RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand.

Science.gov (United States)

Kanamori, Hiroshi; Yuhashi, Kazuhito; Ohnishi, Shin; Koike, Kazuhiko; Kodama, Tatsuhiko

2010-05-01

The hepatitis C virus NS5B RNA-dependent RNA polymerase (RdRp) is a key enzyme involved in viral replication. Interaction between NS5B RdRp and the viral RNA sequence is likely to be an important step in viral RNA replication. The C-terminal half of the NS5B-coding sequence, which contains the important cis-acting replication element, has been identified as an NS5B-binding sequence. In the present study, we confirm the specific binding of NS5B to one of the RNA stem-loop structures in the region, 5BSL3.2. In addition, we show that NS5B binds to the complementary strand of 5BSL3.2 (5BSL3.2N). The bulge structure of 5BSL3.2N was shown to be indispensable for tight binding to NS5B. In vitro RdRp activity was inhibited by 5BSL3.2N, indicating the importance of the RNA element in the polymerization by RdRp. These results suggest the involvement of the RNA stem-loop structure of the negative strand in the replication process.

First draft genome sequencing of indole acetic acid producing and plant growth promoting fungus Preussia sp. BSL10.

Science.gov (United States)

Khan, Abdul Latif; Asaf, Sajjad; Khan, Abdur Rahim; Al-Harrasi, Ahmed; Al-Rawahi, Ahmed; Lee, In-Jung

2016-05-10

Preussia sp. BSL10, family Sporormiaceae, was actively producing phytohormone (indole-3-acetic acid) and extra-cellular enzymes (phosphatases and glucosidases). The fungus was also promoting the growth of arid-land tree-Boswellia sacra. Looking at such prospects of this fungus, we sequenced its draft genome for the first time. The Illumina based sequence analysis reveals an approximate genome size of 31.4Mbp for Preussia sp. BSL10. Based on ab initio gene prediction, total 32,312 coding sequences were annotated consisting of 11,967 coding genes, pseudogenes, and 221 tRNA genes. Furthermore, 321 carbohydrate-active enzymes were predicted and classified into many functional families. Copyright © 2016 Elsevier B.V. All rights reserved.

De werking van de hydro- en acetylverbindingen van kinidine en kinine op het hart van Rana esculenta

NARCIS (Netherlands)

Sibie, Johan Dirk

1942-01-01

In hoofdstuk I werd een inleiding gegeven betreffende de geschiedenis van de kina en van het begin der kinacultuur op Java, de chemie der kinaälkaloïden en enkele aspecten der pharmacologische werking van de kinaderivaten. ... Zie: Samenvatting

Non-Invasive Optical Sensor Based Approaches for Monitoring Virus Culture to Minimize BSL3 Laboratory Entry

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Viswanath Ragupathy

2015-06-01

Full Text Available High titers of infectious viruses for vaccine and diagnostic reference panel development are made by infecting susceptible mammalian cells. Laboratory procedures are strictly performed in a Bio-Safety Level-3 (BSL3 laboratory and each entry and exit involves the use of  disposable Personnel Protective Equipment (PPE to observe cell culture conditions. Routine PPE use involves significant recurring costs. Alternative non-invasive optical sensor based approaches to remotely monitor cell culture may provide a promising and cost effective approach to monitor infectious virus cultures resulting in lower disruption and costs. We report here the monitoring of high titer cultures of Human Immunodeficiency Virus-1 (HIV-1 and Herpes Simplex Virus-2 (HSV-2 remotely with the use of optical oxygen sensors aseptically placed inside the cell culture vessel. The replacement of culture media for cell and virus propagation and virus load monitoring was effectively performed using this fluorescent sensor and resulted in half the number of visits to the BSL3 lab (five versus ten.

Surface-Layer (S-Layer) Proteins Sap and EA1 Govern the Binding of the S-Layer-Associated Protein BslO at the Cell Septa of Bacillus anthracis

Science.gov (United States)

Kern, Valerie J.; Kern, Justin W.; Theriot, Julie A.; Schneewind, Olaf

2012-01-01

The Gram-positive pathogen Bacillus anthracis contains 24 genes whose products harbor the structurally conserved surface-layer (S-layer) homology (SLH) domain. Proteins endowed with the SLH domain associate with the secondary cell wall polysaccharide (SCWP) following secretion. Two such proteins, Sap and EA1, have the unique ability to self-assemble into a paracrystalline layer on the surface of bacilli and form S layers. Other SLH domain proteins can also be found within the S layer and have been designated Bacillus S-layer-associated protein (BSLs). While both S-layer proteins and BSLs bind the same SCWP, their deposition on the cell surface is not random. For example, BslO is targeted to septal peptidoglycan zones, where it catalyzes the separation of daughter cells. Here we show that an insertional lesion in the sap structural gene results in elongated chains of bacilli, as observed with a bslO mutant. The chain length of the sap mutant can be reduced by the addition of purified BslO in the culture medium. This complementation in trans can be explained by an increased deposition of BslO onto the surface of sap mutant bacilli that extends beyond chain septa. Using fluorescence microscopy, we observed that the Sap S layer does not overlap the EA1 S layer and slowly yields to the EA1 S layer in a growth-phase-dependent manner. Although present all over bacilli, Sap S-layer patches are not observed at septa. Thus, we propose that the dynamic Sap/EA1 S-layer coverage of the envelope restricts the deposition of BslO to the SCWP at septal rings. PMID:22609927

Evocatin of the Spirit: A-capella-Werke von Gorecki, Pärt, Martin, Barber und Schönberg / Gerhard Pätzig

Index Scriptorium Estoniae

Pätzig, Gerhard

1995-01-01

Uuest heliplaadist "Evocatin of the Spirit: A-capella-Werke von Gorecki, Pärt, Martin, Barber und Schönberg. Robert Shaw Festival Singers. Robert Shaw (AD: 1994). Telarc/in-akustik CD 80406 (WD: 72'15")

Solar generation of hydrogen; Wasserstofferzeugung auf solarer Basis. Thermische Dissoziation des Wassers mit dem Licht-Kraft-Werk

Energy Technology Data Exchange (ETDEWEB)

Ziemba, G.

2003-04-01

Solar generation of hydrogen. The ''Licht-Kraft-Werke'' (LKW) is described. Due to this it will be possible to supply solid-state-lasers directly by sunlight. Supplied by lasers water should be split in a highest-temperature-reactor. An efficiency of more than 21% is supposed to be reached. (orig.)

Verwaiste und vergriffene Werke - Kommt das 20. Jahrhundert endlich in die Digitale Bibliothek?

Directory of Open Access Journals (Sweden)

Armin Talke

2013-10-01

Full Text Available Am 20.September 2013 hat das am 27. Juni vom Bundestag (Fn 2 verabschiedete Gesetz zur Nutzung verwaister und vergriffener Werke auch den Bundesrat passiert. Es entspricht weitgehend dem Entwurf der Bundesregierung (Fn 3. Kleinere, vom Rechtsausschuss vorgeschlagene (Fn 4 Änderungen sind eingeflossen. Der Regelung liegt zum Teil die Richtlinie 2012/28/EU vom 25. Oktober 2012 über bestimmte zulässige Nutzungen verwaister Werke zugrunde. Nachdem lange Zeit von vielen Interessengruppen eine Weiterentwicklung des Urheberrechts gefordert wurde, haben die Deutschen Gesetzgebungsorgane mit der Regelung in §§ 61 ff UrhG zu den verwaisten und in §§ 13d und e UrhWahrnG zu den vergriffenen Werken, neben den gleichzeitig verabschiedeten Vorgaben für ein „Zweitverwertungsrecht”, in aller Eile vor der Sommerpause und der Bundestagswahl einen kleinen Fortschritt getan. In europarechtlicher Hinsicht wäre die Regelung so schnell gar nicht notwendig gewesen: Die Umsetzungsfrist läuft nach Art. 9 Abs.1 der Richtlinie erst zum 29.9.2014 ab. Auch inhaltlich übertrifft das Gesetz mit der Normierung der Lizenzierung „vergriffener” Werke durch Verwertungsgesellschaften die zwingenden Vorgaben der Richtlinie. Ein neues „Kapitel in der Geschichte des Urheberrechts”, das von der Bundesjustizministerin schon im Juni 2010 angemahnt worden war (Fn 5, ist damit allerdings noch nicht geschrieben. Die Richtlinie und das Gesetz erlauben die Digitalisierung von noch urheberrechtlich geschützten Werktypen verschiedenster Art, die in unterschiedlichen Kultureinrichtungen vorhanden sind. Die folgenden Ausführungen beziehen sich vorwiegend auf die Nutzung gedruckter Literatur. In September, 2013, the German legislators adopted the law on orphan works and out-of-print-works. Both categories affect works which are still under copyright. The clash of interests, however, of cultural institutions holding items of these works, and rightsholders, are not serious, as

Genome sequence of the photoarsenotrophic bacterium Ectothiorhodospira sp. strain BSL-9, isolated from a hypersaline alkaline arsenic-rich extreme environment

Science.gov (United States)

Hernandez-Maldonado, Jaime; Stoneburner, Brendon; Boren, Alison; Miller, Laurence; Rosen, Michael R.; Oremland, Ronald S.; Saltikov, Chad W

2016-01-01

The full genome sequence of Ectothiorhodospira sp. strain BSL-9 is reported here. This purple sulfur bacterium encodes an arxA-type arsenite oxidase within the arxB2AB1CD gene island and is capable of carrying out “photoarsenotrophy” anoxygenic photosynthetic arsenite oxidation. Its genome is composed of 3.5 Mb and has approximately 63% G+C content.

Personeel van sociale instituties. Over het verband tussen vrouwenbeweging en maatschappelijk werk

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Berteke Waaldijk

2015-06-01

Full Text Available Staffing Social Institutions: The Relation between the Women’s Movement and Social WorkBerteke Waaldijk discusses the way ideals of feminism and women’s emancipation in the Netherlands found their way into the design and delivery of social interventions. She compares ideals of women’s movement around 1913 with practices designed by the ‘Benevolent Colonies’ in the 1820s for Dutch paupers and with the feminist training for social workers of the 1970s and 1980s in the Netherlands. She concludes that ideals about the liberation of women were often expressed as those of professional social work aimed at making clients (‘paupers’ in 1820, ‘the poor’ in 1913 become self-reliant citizens. Respect for clients and trainedexpertise of the social workers were the requirement for such social interventions. In the examples discussed disciplinary practices and emancipatory ideals are not mutually exclusive. More research therefore is required on the way connections between feminist movements and training for social professionals facilitate disciplining social policies.Berteke Waaldijk bespreekt de historische vervlechting tussen vrouwenbewegingen en sociale interventies. Uit een vergelijking van de idealen van het sociaal werk rond 1913 met de praktijken van de Maatschappij voor Weldadigheid concludeert zij dat nadruk op zelfredzaamheid van de cliënt en respect en deskundigheid van de hulpverlener niet nieuw waren. De idealen van Hélène Mercier en MarieMuller-Lulofs rond 1900 leken in veel opzichten op de idealen van dat oudere disciplinerende sociale project. Met een beschrijving van de idealen van de tweede feministische golf binnen de sociale beroepsopleiding ‘Vrouwen en Welzijnswerk’ laat Waaldijk zien dat ook in de jaren zeventig en tachtig van de twintigste eeuwfeministische idealen soms geformuleerd werden als pleidooien voor professioneel sociaal werk. De rol van de denkbeelden over bevrijding en emancipatie van vrouwen in het

Sammelband zum Werk von Marieluise Fleißer An Anthology of the Work by Marieluise Fleißer

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Karin Windt

2002-07-01

Full Text Available Der Sammelband zu Marieluise Fleißer (1901–1974 beschäftigt sich mit ästhetischen und rhetorischen Strukturen ihrer Texte. Die Beiträge umfassen dabei das gesamte Spektrum des Werkes der Dichterin von der Weimarer Zeit bis in die siebziger Jahre.This anthology of articles on the asthetics and rethorics of Marieluise Fleißer’s work investigates her complete works, dating back from the time of the Weimar Rebublic to the 1970s.

Planning of a small hydroelectric installation project - orientation aids; Vom Plan zum Werk - Orientierungshilfen

Energy Technology Data Exchange (ETDEWEB)

Hutarew, A. [Dr. Hutarew und Partner, Pforzheim (Germany)

1997-12-31

The article informs in concise form on essential elements of the plannning of a small hydro power project. Understanding and considerateness are demanded from all parties concerned when such a joint project is envisaged. Not one-sided interests should be followed; rather, everyone should contribute towards facilitating renewable energy generation. Some negative examples are cited. (orig.) [Deutsch] In der Kuerze der gebotenen Zeit wurde versucht, wesentliche Eckpfeiler in der Entstehung einer Wasserkraftanlage zu skizzieren. Ziel meiner Ausfuehrungen ist es, von allen Beteiligten Verstaendnis abzuverlangen und Ruecksichtnahme zu praktizieren, geht es doch darum, ein gemeinsames Werk entstehen zu lassen. Wir stehen nicht in der Not, einseitige Interessen zu verfechten, sondern gemeinsam an einem Baustein regenerativer Energieerzeugung zu arbeiten. Es sei mir verziehen, wenn durch die Schilderung von Negativ-Beispielen ein eher unueblicher Weg beschritten wurde. (orig.)

Establishment of Biosafety Level-3 (BSL-3 laboratory: Important criteria to consider while designing, constructing, commissioning & operating the facility in Indian setting

Directory of Open Access Journals (Sweden)

Devendra T Mourya

2014-01-01

This article describes the major steps involved in the process of construction of a BSL-3 laboratory in Indian settings, from freezing the concept of proposal to operationalization phase. The key to success of this kind of project is strong institutional commitment to biosafety norms, adequate fund availability, careful planning and designing, hiring good construction agency, monitoring by experienced consultancy agency and involvement of scientific and engineering personnel with biocontainment experience in the process.

DIFFERENCES BETWEEN AMERICAN SIGN LANGUAGE (ASL AND BRITISH SIGN LANGUAGE (BSL

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Zora JACHOVA

2008-06-01

Full Text Available In the communication of deaf people between them­selves and hearing people there are three ba­sic as­pects of interaction: gesture, finger signs and writing. The gesture is a conditionally agreed manner of communication with the help of the hands followed by face and body mimic. The ges­ture and the move­ments pre-exist the speech and they had the purpose to mark something, and later to emphasize the speech expression.Stokoe was the first linguist that realised that the signs are not a whole that can not be analysed. He analysed signs in insignificant parts that he called “chemeres”, and many linguists today call them pho­nemes. He created three main phoneme catego­ries: hand position, location and movement.Sign languages as spoken languages have back­ground from the distant past. They developed par­allel with the development of spoken language and undertook many historical changes. Therefore, to­day they do not represent a replacement of the spoken language, but are languages themselves in the real sense of the word.Although the structures of the English language used in USA and in Great Britain is the same, still their sign languages-ASL and BSL are different.

Tanne plant - first results of soil treatment according to the anaerobic/aerobic method; Werk Tanne - Erste Ergebnisse der Bodenbehandlung nach dem Anaerob-Aerob-Verfahren

Energy Technology Data Exchange (ETDEWEB)

Fischer, D.; Walter, U. [Umweltschutz Nord GmbH, Ganderkesee (Germany)

1999-02-01

Biological remediation of STV contaminated sites has been a major focus of the promotion activities of the Federal Research and Education Ministry (BMFB) for some years now. For this purpose the BMFB has drawn together diverse integrated research projects to bring a well-coordinated force of activities to bear on this problem in a manner unprecedented in Germany. Its declared aim in doing so is, firstly, to compile a guide on biological remediation and, secondly, to funnel the output of all ongoing German research in this field into the second phase of its research activities at the ''Tanne'' plant in Clausthal-Zellerfeld, which is dedicated to practice-oriented testing of methods for the biological remediation of STV contaminated sites. [German] Die biologische Sanierung von Standorten, welche mit STV kontaminiert sind, ist seit einigen Jahren eines der markanten Ziele der BMBF-Forschungsfoerderungen. Durch die bislang in der bundesweiten Forschung einmalige, Forschungsverbund uebergreifende, koordinierte Buendelung saemtlicher wissenschaftlicher Aktivitaeten ist es erklaertes Ziel, zum einen einen Leitfaden zur biologischen Sanierung herauszuarbeiten, zum anderen, die aktuellen, bundesweiten, wissenschaftlichen Erkenntnisse in die seit Mai 1998 am Standort 'Werk Tanne' in Clausthal-Zellerfeld laufende Phase 2 der BMBF-Forschungsaktivitaeten, naemlich die praxisorientierte Erprobung von Verfahren zur biologischen Sanierung von STV-belasteten Standorten, einzugreifen. (orig.)

Sociolinguistic Variation and Change in British Sign Language Number Signs: Evidence of Leveling?

Science.gov (United States)

Stamp, Rose; Schembri, Adam; Fenlon, Jordan; Rentelis, Ramas

2015-01-01

This article presents findings from the first major study to investigate lexical variation and change in British Sign Language (BSL) number signs. As part of the BSL Corpus Project, number sign variants were elicited from 249 deaf signers from eight sites throughout the UK. Age, school location, and language background were found to be significant…

Βιβλιοκρισία:P. SCHREINER-E. VOGT(eds., Karl Krumbacher. Leben und Werk, München, Verlag der Bayerischen Akademie der Wissenschaften in Kommission beim Verlag C. H. Beck, München 2011

Directory of Open Access Journals (Sweden)

Walter PUCHNER

2013-04-01

Full Text Available Βιβλιοκρισία: P. Schreiner-E. Vogt (eds., Karl Krumbacher. Leben und Werk, München, Verlag der Bayerischen Akademie der Wissenschaften in Kommission beim Verlag C. H. Beck, München 2011 (Bayerische Akademie der Wissenschaften, Philosophisch-historische Klasse, Sitzungsberichte, Jahrgang 2011, Heft 4, σελ. 147, 5 εικ., ΙSBN 978 3 7696 1569 0.

UBER DEN BEITRITT DER PLURIMODALITÄT DES VERSTEHENS DER NICHTEUROPÄISCHEN TRADITION. DISCOURS ÜBER DISCOURS. (PROBLEMATISIERUNG INITIERT MIT DEM WERK "CARSTVO ZNAKOVA" VON ROLAND BARTHES, AUGUST CESAREC, ZAGREB 1989

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Jadran Zalokar

1990-01-01

Full Text Available In diesem Text problematisiert der Verfasser manche grundsätzlicke Fragen des Verstehens nichteuropäischen Traditionen im Ganzen. Dabei analysiert er das Werk von Roland Barthes in Zusammenhang des Verstehens der Beziehung textuallen im Gegensatz zum geistlichen Tradition Japans, gleichzeitig auf die methodologisch wichtige Frage hinweisend. Alles enken und "Schreiben" darüber ist in nuce zweifelhaft. Das Denken des planetaren Polilogen als Multiloge verlangt einen strengen wissenschaftlichen Beitritt, aber auch einen metawissenschaftlichen und metaphilosphischen Einblick in das geistliche Wesen nichteuropäischen Tradition, weil es gleichmäßige Beachtung verschiedensten geistlichen Erfahrungen und Eingenartigkeiten des geistlichen Lebens aller Traditionen nötig ist und nurwissenschaftlicher und nurphilosophischer Beitritt ist nicht genügend.

Drie redenen waarom mensen zich zonder betaling ten volle inzetten: opiniërend

NARCIS (Netherlands)

Ridder Schueren van der, M. de; Zwetsloot, G.

2016-01-01

Terwijl betaald werk steeds meer wordt gerationaliseerd en door managers, aangestuurd met veelal primair een financiële doelstelling, ligt dat heel anders bij vrijwillig werk. Bij het verrichten van betaald werk is het genereren van inkomen voor velen essentieel. Vrijwillig werk wordt niet betaald,

Análisis, implementación y evaluación de prácticas con el equipo Biopac BSL MP45 para el Laboratorio de Ingeniería Biomédica de la UPS

OpenAIRE

Montesdeoca Contreras, Julio César

2014-01-01

La Universidad Politécnica Salesiana lleva a cabo el proyecto "Diseño de un Laboratorio de Ingeniería Biomédica", el documento consta del diseño del manual para el equipo Biopac BSL MP45, prácticas de adquisición y reconocimiento de las bioseñales EMG, ECG, EEG y EOG; se describe la naturaleza de las bioseñales, la estructura de diseño de las prácticas así como de los protocolo por cada tipo de bioseñal a adquirir. The Universidad Politécnica Salesiana carried out the project "Design of a ...

Remediation of the Lermontov mining site in Russia; Sanierung des Bergbaustandortes Lermontov in Russland

Energy Technology Data Exchange (ETDEWEB)

Krotkov, V.V. [Atomredmetzoloto, Moscow (Russian Federation)

2001-07-01

For 40 years, uranium mines were operated in the direct vicinity of the spas of Mineralnyje Wody, Pjatigorsk, Kislowodsk, Jessentuki and Shelesnowodsk by the Almaz company. Now that the mines have been abandoned, the spa region is surrounded by contaminated land. Remedial measures are projected in accordance with radiation protection standards. [German] 40 Jahre lang wurde Uranerzbergbau und -aufbereitung in unmittelbarer Naehe der Kurorte Mineralnyje Wody, Pjatigorsk, Kislowodsk, Jessentuki und Shelesnowodsk durch das Unternehmen Almaz betrieben. Gegenwaertig sind die Aktivitaeten des Unternehmens vollstaendig eingestellt. Als Folge entstanden im Gebiet der Kaukasischen Mineralbaeder uranhaltige Halden am Berg Beschtau mit einer Flaeche von 36,0 ha und am Berg Byk mit einer Flaeche von 18,4 ha. Im hydrometallurgischen Werk sind 44,5 ha Betriebsgelaende kontaminiert, wo sich Bauten fuer die Grund- und Hilfsproduktion, Erzlager, das werkseigene Chemielabor und das Heizkraftwerk befinden. Die IAA liegt 1,5 km vom Betriebsgelaende des hydrometallurgischen Werks entfernt und besteht aus fuenf Becken, wo von 1954 bis 1991 Rueckstaende der Uranproduktion eingelagert wurden. Seit 1991 gelangte dorthin Phosphorgips als Abprodukt der Verarbeitung von Apatit. Das sechste Becken ist fuer die Aufnahme von Wasser bei Stoerfaellen in den Hauptbecken bestimmt. Die IAA mit den angrenzenden Flaechen soll saniert werden. Vorrangig gilt es, geschaedigte Flaechen wiederherzustellen und die Situation im Bereich der IAA entsprechend den Normen des Strahlenschutzes sicher zu gestalten. Der Massnahmenkomplex fuer die Sanierung des Territoriums beinhaltet - Stillegung der abgearbeiteten Schlammbecken der IAA, - Rekultivierung der geschaedigten Flaechen im Bergbaugebiet, - Dekontamination der anliegenden kontaminierten Flaechen mit Background-{gamma}+20 {mu}R/h, - Schutz der Grundwaesser vor Kontamination durch eingelagerte Tailings des hydrometallurgischen Werks, - gesteurte Ableitung der

Evaluating the prevalence and effectiveness of breed-specific legislation

OpenAIRE

Trembath, Felicia E

2016-01-01

Dog bites pose a persistent public health problem, which some jurisdictions pass breed-specific legislation (BSL) to address. However, very little non-anecdotal evidence regarding the efficacy of BSL has been presented. Currently, BSL research is hampered by the absence of standard terminology, an established prevalence, or a scientific consensus on its effectiveness. The purpose of this study is to propose standardized terminology for BSL, establish the prevalence of each type of BSL in the ...

Optimal management of the power distribution network. A novel network information system; Optimale Verwaltung des Versorgungsnetzes. Ein neues Netzinformationssystem

Energy Technology Data Exchange (ETDEWEB)

Kiesel, U. [HEW AG, Hamburg (Germany); Korri, P. [Tekla Qyj, Eschborn (Germany). Energieversorgung

2000-12-01

In June 200, the German electric utility Hamburgische Electricitaets-Werke AG (HEW) has bought and installed a high-performance, PC-based information system for all purposes of distribution network management tasks for their medium and low-voltage grids. The standard software Xpower of the Finnish software house Tekla Oyj has been streamlined with the requirements of the utility and is described with respect to the applications on site. (orig./CB) [German] Mit der Einfuehrung eines Netzinformationssystems (NIS) steht der Hamburgischen Electricitaets-Werke AG (HEW) seit Juni 2000 ein leistungsstarkes PC-basiertes Informationssystem zur Verfuegung, das langfristig die Projektierung und die Betriebsfuehrung der Mittel- und Niederspannungsnetze unterstuetzt und dokumentiert. Die Standardsoftware Xpower des finnischen Spezialisten Tekla Oyj wurde an die Anforderungen der HEW angepasst. (orig./CB)

Early burn wound excision and skin grafting postburn trauma restores in vivo neutrophil delivery to inflammatory lesions

International Nuclear Information System (INIS)

Tchervenkov, J.I.; Epstein, M.D.; Silberstein, E.B.; Alexander, J.W.

1988-01-01

This study assessed the effect of early vs delayed postburn wound excision and skin grafting on the in vivo neutrophil delivery to a delayed-type hypersensitivity (DTH) reaction and a bacterial skin lesion (BSL). Male Lewis rats were presensitized to keyhole-limpet hemocyanin. Group 1 comprised sham controls. Groups 2 through 4 were given a 30% 3 degrees scald burn, but the burn wounds were excised, and skin was grafted on days 1, 3, and 7, respectively, after the burn. Group 5 comprised burn controls. Twelve days after burn trauma, all rats were injected at different intervals (during a 24-hour period) with a trio of intradermal injections of keyhole-limpet hemocyanin, Staphylococcus aureus 502A, and saline at different sites. In vivo neutrophil delivery to these dermal lesions was determined by injecting indium in 111 oxyquinoline-labeled neutrophils isolated from similarly treated groups of rats. Neutrophil delivery to DTH and BSL lesions was restored to normal by excision and skin grafting of the burn wound one day after burn trauma. Waiting three days after burn trauma to excise and skin graft the wound partially, but not completely, restored the in vivo neutrophil delivery to DTH and BSL lesions. Waiting one week to excise and skin graft a burn wound resulted in no improvement in neutrophil delivery to DTH and BSL dermal lesions. It was concluded that burn wound excision and skin grafting immediately after burn trauma restored in vivo neutrophil delivery to a BSL and DTH dermal lesion. This may, in part, explain the beneficial effect of early aggressive burn wound debridement in patients with burn injuries

De digitale stresscoach : totale controle over je mentale gezondheid of Big Brother is watching you?

NARCIS (Netherlands)

Lieshout, M. van; Wiezer, N.; Korte, E. de

2014-01-01

Een digitale coach die je helpt stress op je werk te verminderen en meer energie uit je werk te halen klinkt aantrekkelijk. Stress ervaren we immers allemaal. Net zoals we allemaal streven naar werk waar je energie van krijgt. En stress vermijden we liever. Stress is een maatschappelijk probleem en

Evaluating the efficacy of hydrogen peroxide vapour against foot-and-mouth disease virus within a BSL4 biosafety facility.

Science.gov (United States)

Petit, B M; Almeida, F C; Uchiyama, T R; Lopes, F O C; Tino, K H; Chewins, J

2017-10-01

An evaluation was made of the efficacy of 35% hydrogen peroxide vapour (HPV) against foot-and-mouth disease virus (FMDV) in a biosafety facility. Biological indicators (BIs) were produced using three serotypes of FMDV, all with a titre of ≥10 6 TCID 50 per ml. Fifteen BIs of each serotype were distributed across five locations, throughout a 30-m 3 airlock chamber, producing a total of 45 BIs. Thirty-five percent HPV was generated and applied using a Bioquell vaporization module located in the centre of the chamber. After a dwell period of 40 min, the HPV was removed via the enclosures air handling system and the BIs were collected. The surfaces of the BIs were recovered into Glasgow's modified Eagle's medium (GMEM), cultivated in BHK21 Cl13 cell culture and analysed for evidence of cytopathic effect (CPE). No CPE was detected in any BI sample. Positive controls showed CPE. The experimentation shows that FMDV is susceptible to HPV decontamination and presents a potential alternative to formaldehyde. Foot-and-mouth disease virus (FMDV) is an important pathogen in terms of biosafety due to its infectious nature and wide range of host animals, such as cattle, sheep, goats and pigs. Outbreaks of FMDV can have a severe impact on livestock production, causing morbidity, mortality, reduced yields and trade embargoes. Laboratories studying FMDV must possess BSL4 robust bio-decontamination methods to prevent inadvertent release. Formaldehyde has been the primary agent for environmental decontamination, but its designation as a human carcinogen has led to a search for alternatives. This study shows 35% hydrogen peroxide vapour has the potential to be a rapid, effective, residue-free alternative. © 2017 The Society for Applied Microbiology.

Wireless connection of continuous glucose monitoring system to the electronic patient record

Science.gov (United States)

Murakami, Alexandre; Gutierrez, Marco A.; Lage, Silvia G.; Rebelo, Marina S.; Granja, Luiz A. R.; Ramires, Jose A. F.

2005-04-01

The control of blood sugar level (BSL) at near-normal levels has been documented to reduce both acute and chronic complications of diabetes mellitus. Recent studies suggested, the reduction of mortality in a surgical intensive care unit (ICU), when the BSL are maintained at normal levels. Despite of the benefits appointed by these and others clinical studies, the strict BSL control in critically ill patients suffers from some difficulties: a) medical staff need to measure and control the patient"s BSL using blood sample at least every hour. This is a complex and time consuming task; b) the inaccuracy of standard capillary glucose monitoring (fingerstick) in hypotensive patients and, if frequently used to sample arterial or venous blood, may lead to excess phlebotomy; c) there is no validated procedure for continuously monitoring of BSL levels. This study used the MiniMed CGMS in ill patients at ICU to send, in real-time, BSL values to a Web-Based Electronic Patient Record. The BSL values are parsed and delivered through a wireless network as an HL7 message. The HL7 messages with BSL values are collected, stored into the Electronic Patient Record and presented into a bed-side monitor at the ICU together with other relevant patient information.

Evaluation of cellulose-binding domain fused to a lipase for the lipase immobilization.

Science.gov (United States)

Hwang, Sangpill; Ahn, Jungoh; Lee, Sumin; Lee, Tai Gyu; Haam, Seungjoo; Lee, Kangtaek; Ahn, Ik-Sung; Jung, Joon-Ki

2004-04-01

A cellulose-binding domain (CBD) fragment of a cellulase gene of Trichoderma hazianum was fused to a lipase gene of Bacillus stearothermophilus L1 to make a gene cluster for CBD-BSL lipase. The specific activity of CBD-BSL lipase for oil hydrolysis increased by 33% after being immobilized on Avicel (microcrystalline cellulose), whereas those of CBD-BSL lipase and BSL lipase decreased by 16% and 54%, respectively, after being immobilized on silica gel. Although the loss of activity of an enzyme immobilized by adsorption has been reported previously, the loss of activity of the CBD-BSL lipase immobilized on Avicel was less than 3% after 12 h due to the irreversible binding of CBD to Avicel.

Theory Meets Experiment: Metal Ion Effects in HCV Genomic RNA Kissing Complex Formation

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Li-Zhen Sun

2017-12-01

Full Text Available The long-range base pairing between the 5BSL3. 2 and 3′X domains in hepatitis C virus (HCV genomic RNA is essential for viral replication. Experimental evidence points to the critical role of metal ions, especially Mg2+ ions, in the formation of the 5BSL3.2:3′X kissing complex. Furthermore, NMR studies suggested an important ion-dependent conformational switch in the kissing process. However, for a long time, mechanistic understanding of the ion effects for the process has been unclear. Recently, computational modeling based on the Vfold RNA folding model and the partial charge-based tightly bound ion (PCTBI model, in combination with the NMR data, revealed novel physical insights into the role of metal ions in the 5BSL3.2-3′X system. The use of the PCTBI model, which accounts for the ion correlation and fluctuation, gives reliable predictions for the ion-dependent electrostatic free energy landscape and ion-induced population shift of the 5BSL3.2:3′X kissing complex. Furthermore, the predicted ion binding sites offer insights about how ion-RNA interactions shift the conformational equilibrium. The integrated theory-experiment study shows that Mg2+ ions may be essential for HCV viral replication. Moreover, the observed Mg2+-dependent conformational equilibrium may be an adaptive property of the HCV genomic RNA such that the equilibrium is optimized to the intracellular Mg2+ concentration in liver cells for efficient viral replication.

Psychometric Properties of the Chinese Version of the Brief Borderline Symptom List in Undergraduate Students and Clinical Patients

Directory of Open Access Journals (Sweden)

Huihui Yang

2018-04-01

Full Text Available The brief version of the Borderline Symptom List (BSL-23 is a self-rated scale developed from the initial 95-item version of Borderline Symptom List (BSL-95. The current study aimed to evaluate the psychometric properties of the Chinese version of the BSL-23. A total of 570 undergraduate students and 323 clinical patients completed the BSL-23, the borderline subscale of the Personality Diagnostic Questionnaire (PDQ-4+, the Center for Epidemiologic Studies Depression Scale (CES-D, the Barratt Impulsiveness Scale, 11th version (BIS-11, the Childhood Trauma Questionnaire (CTQ and the Attachment Style Questionnaire (ASQ. A Confirmatory Factor Analysis (CFA was conducted to test the one-factor structure of the BSL-23. Cronbach’s alpha, Omega coefficient, Split-Half coefficient, Mean Inter-Item Correlation (MIC and test-retest reliability were also measured. The correlations between the BSL-23 and other psychological variables were used to assess criterion-related validity and convergent validity. Participants who scored ≥ 5 on the borderline subscale of the PDQ-4+ were placed into the borderline personality disorder (BPD screening-positive group, while the others were placed into the screening-negative group. Independent sample t-tests were performed to examine the differences in BSL-23 scores between the BPD screening-positive group and the BPD screening-negative group. The CFA results supported the one-factor structure of the BSL-23 in both samples. The internal consistency was high both in the undergraduate sample (Cronbach’s α = 0.93, Omega = 0.95, Split-Half coefficient = 0.89, MIC = 0.38 and the clinical sample (Cronbach’s α = 0.97, Omega = 0.97, Split-Half coefficient = 0.96, MIC = 0.56. The test-retest reliability within 2 weeks was 0.62. The BSL-23 displayed moderate to high correlations with the PDQ-4+-Borderline subscale, the CES-D, the BIS-11, the CTQ and the ASQ (r = 0.35 – 0.70. In addition, the BSL-23 discriminated between

Psychometric Properties of the Chinese Version of the Brief Borderline Symptom List in Undergraduate Students and Clinical Patients.

Science.gov (United States)

Yang, Huihui; Lei, Xiaoxia; Zhong, Mingtian; Zhou, Qi; Ling, Yu; Jungkunz, Martin; Yi, Jinyao

2018-01-01

The brief version of the Borderline Symptom List (BSL-23) is a self-rated scale developed from the initial 95-item version of Borderline Symptom List (BSL-95). The current study aimed to evaluate the psychometric properties of the Chinese version of the BSL-23. A total of 570 undergraduate students and 323 clinical patients completed the BSL-23, the borderline subscale of the Personality Diagnostic Questionnaire (PDQ-4+), the Center for Epidemiologic Studies Depression Scale (CES-D), the Barratt Impulsiveness Scale, 11th version (BIS-11), the Childhood Trauma Questionnaire (CTQ) and the Attachment Style Questionnaire (ASQ). A Confirmatory Factor Analysis (CFA) was conducted to test the one-factor structure of the BSL-23. Cronbach's alpha, Omega coefficient, Split-Half coefficient, Mean Inter-Item Correlation (M IC ) and test-retest reliability were also measured. The correlations between the BSL-23 and other psychological variables were used to assess criterion-related validity and convergent validity. Participants who scored ≥ 5 on the borderline subscale of the PDQ-4+ were placed into the borderline personality disorder (BPD) screening-positive group, while the others were placed into the screening-negative group. Independent sample t -tests were performed to examine the differences in BSL-23 scores between the BPD screening-positive group and the BPD screening-negative group. The CFA results supported the one-factor structure of the BSL-23 in both samples. The internal consistency was high both in the undergraduate sample (Cronbach's α = 0.93, Omega = 0.95, Split-Half coefficient = 0.89, M IC = 0.38) and the clinical sample (Cronbach's α = 0.97, Omega = 0.97, Split-Half coefficient = 0.96, M IC = 0.56). The test-retest reliability within 2 weeks was 0.62. The BSL-23 displayed moderate to high correlations with the PDQ-4+-Borderline subscale, the CES-D, the BIS-11, the CTQ and the ASQ ( r = 0.35 - 0.70). In addition, the BSL-23 discriminated between the BPD

Screening of Indian medicinal plants for cytotoxic activity by Brine Shrimp Lethality (BSL assay and evaluation of their total phenolic content

Directory of Open Access Journals (Sweden)

Mahesh Biradi

2014-01-01

Full Text Available Objective: Plant-derived cytotoxic constituents and polyphenolic compounds have played an important role in the development of clinically useful anticancer agents. In this context, we have selected six Indian medicinal plants based on the literature claims and an attempt was made to evaluate the cytotoxic potential and total phenolic content (TPC of their methanol extracts and fractions. Materials and Methods: Six plants have been selected for the study, namely, Artemisia absinthium Linn. (Asteraceae, Oroxylum indicum (Linn. Vent. (Bignoniaceae, Heliotropium indicum Linn. (Boraginaceae, Amorphophallus sylvaticus (Roxb. Kunth. (Araceae, Mimosa pudica Linn. (Mimosaceae, and Premna serratifolia Linn. (Verbenaceae. Authenticated plant materials were subjected to extraction with methanol by cold maceration and hot percolation methods. The extracts were fractionated into four fractions (F1, F2, F3, and F4. Preliminary phytochemical investigation was carried out for all extracts and fractions. All extracts and their fractions were subjected to cytotoxicity screening by brine shrimp lethality (BSL bioassay. The plants with significant cytotoxicity were evaluated for TPC by using Folin-Ciocalteu reagent. Results: F1, F2, and F3 fractions of A. absinthium and P. serratifolia and F1 fraction of M. pudica have shown significant cytotoxicity (lethal concentration (LC 50 < 100 ppm compared with other fractions. F1, F2, and F3 fractions of A. absinthium show the LC 50 values 32.52, 14.27, and 24.02, respectively; F1, F2, and F3 of P. serratifolia show LC 50 values 7.61, 4.01, and 10.91 and same for F1 fraction of M. pudica was 34.82 μg/ml, respectively. TPC was found to be significantly higher (39.11 mg gallic acid equivalent (GAE/g in P. serratifolia compared with other two plants. Conclusion: The cytotoxicity screening system confirmed the proposed anticancer plants used by traditional healers and literature claims.

Die kliniese kindersielkundige as diagnostikus1

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D. J. W. Strümpfer

1961-03-01

Full Text Available Die benaming „Kliniese Kindersielkunde” is nog onbekend en gevolglik betreklik onbemind. Dit is in 1951 die eerste keer gebruik. Die werk van die Kliniese Kindersielkunde is egter so oud as die werk van die algemene Kliniese Sielkunde, waarvan die geskiedenis gewoonlik teruggevoer word tot die begin van sielkundige toetsing vroeg in die tagtigerjare. Tot ’n aansienlike mate is hierdie vroeë werk op kinders uitgevoer, bv. dié van Galton en later die van Binet en Simon. Witmer het in 1896 die eerste sielkundige kliniek geopen en het ook die term „Kliniese Sielkunde” ingevoer; die meerderheid van sy pasiënte was egter ook kinders. Tot voor die Tweede Wêreldoorlog was klinies-sielkundige werk hoofsaaklik op kinders toegespits. Sedertdien het die kliniese sielkundige tot ’n belangrike mate toegetree tot die gebied van die diagnose en terapie van psigiese afwykings by volwassenes, tot so ’n mate dat in die gedagtes en geskrifte van baie werkers die terrein van die Kliniese Sielkunde byna tot werk met volwassenes beperk word.

The Influence of Deaf People's Dual Category Status on Sign Language Planning: The British Sign Language (Scotland) Act (2015)

Science.gov (United States)

De Meulder, Maartje

2017-01-01

Through the British Sign Language (Scotland) Act, British Sign Language (BSL) was given legal status in Scotland. The main motives for the Act were a desire to put BSL on a similar footing with Gaelic and the fact that in Scotland, BSL signers are the only group whose first language is not English who must rely on disability discrimination…

Work-Life Balance: A Study In The Petroleum Industry

Directory of Open Access Journals (Sweden)

Judy De Villiers

2003-11-01

’n Kwalitatiewe studie is onderneem om vas te stel hoe die werknemers van ’n maatskappy in die petroleumnywerheid die fenomeen van die werk-lewe ewewig definieer en ervaar, om die werkpleksdeterminante van ’n werk-lewe onewewigtigheid te identifiseer en om sekere oplossings vir die probleem aan die hand te doen. Dit is gevind dat werk-lewe ewewig ’n persoonlike saak is wat oor tyd en omstandighede varieer en die ervaarde onderliggende konflik na roloorladingsrolle en -inmenging verwys. Die mees betekenisvolle werk-lewe konflik tree na vore vanuit komplekse werkplekaangeleenthede, insluitende die bestuur van veranderings, toesighoudende en tegniese vaardighede, leierskap, rolle en aanspreeklikheid, asook kultuur. Oplossings om die werkpleksake aan te spreek, asook die ontwikkeling van individuele vaardighede om ’n ewewig teweeg te bring, word voorgestel.

Biosafety standards for working with Crimean-Congo hemorrhagic fever virus.

Science.gov (United States)

Weidmann, Manfred; Avsic-Zupanc, Tatjana; Bino, Silvia; Bouloy, Michelle; Burt, Felicity; Chinikar, Sadegh; Christova, Iva; Dedushaj, Isuf; El-Sanousi, Ahmed; Elaldi, Nazif; Hewson, Roger; Hufert, Frank T; Humolli, Isme; Jansen van Vuren, Petrus; Koçak Tufan, Zeliha; Korukluoglu, Gülay; Lyssen, Pieter; Mirazimi, Ali; Neyts, Johan; Niedrig, Matthias; Ozkul, Aykut; Papa, Anna; Paweska, Janusz; Sall, Amadou A; Schmaljohn, Connie S; Swanepoel, Robert; Uyar, Yavuz; Weber, Friedemann; Zeller, Herve

2016-11-01

In countries from which Crimean-Congo haemorrhagic fever (CCHF) is absent, the causative virus, CCHF virus (CCHFV), is classified as a hazard group 4 agent and handled in containment level (CL)-4. In contrast, most endemic countries out of necessity have had to perform diagnostic tests under biosafety level (BSL)-2 or -3 conditions. In particular, Turkey and several of the Balkan countries have safely processed more than 100 000 samples over many years in BSL-2 laboratories. It is therefore advocated that biosafety requirements for CCHF diagnostic procedures should be revised, to allow the tests required to be performed under enhanced BSL-2 conditions with appropriate biosafety laboratory equipment and personal protective equipment used according to standardized protocols in the countries affected. Downgrading of CCHFV research work from CL-4, BSL-4 to CL-3, BSL-3 should also be considered.

Framework for leadership and training of Biosafety Level 4 laboratory workers.

Science.gov (United States)

Le Duc, James W; Anderson, Kevin; Bloom, Marshall E; Estep, James E; Feldmann, Heinz; Geisbert, Joan B; Geisbert, Thomas W; Hensley, Lisa; Holbrook, Michael; Jahrling, Peter B; Ksiazek, Thomas G; Korch, George; Patterson, Jean; Skvorak, John P; Weingartl, Hana

2008-11-01

Construction of several new Biosafety Level 4 (BSL-4) laboratories and expansion of existing operations have created an increased international demand for well-trained staff and facility leaders. Directors of most North American BSL-4 laboratories met and agreed upon a framework for leadership and training of biocontainment research and operations staff. They agreed on essential preparation and training that includes theoretical consideration of biocontainment principles, practical hands-on training, and mentored on-the-job experiences relevant to positional responsibilities as essential preparation before a person's independent access to a BSL-4 facility. They also agreed that the BSL-4 laboratory director is the key person most responsible for ensuring that staff members are appropriately prepared for BSL-4 operations. Although standardized certification of training does not formally exist, the directors agreed that facility-specific, time-limited documentation to recognize specific skills and experiences of trained persons is needed.

Naar een dashboard duurzame inzetbaarheid

NARCIS (Netherlands)

Blatter, B.; Dorenbosch, L.; Keijzer, L.

2015-01-01

Vlaanderen kent de Monitor Werkbaar Werk als informatiebron over de kwaliteit van werk voor de Vlaamse Regering, sociale partners, werkgevers en andere arbeidsmarktpartijen. Nederland kent sinds 2010 een soortgelijk instrument: het Dashboard Duurzame Inzetbaarheid. In deze bijdrage zetten we het

Occupational hazard? The relationship between working conditions and fertility

NARCIS (Netherlands)

Begall, Katia Hildegard

2013-01-01

De arbeidsmarktparticipatie van vrouwen en moeders is tegenwoordig maatschappelijk geaccepteerd en vaak ook nodig om te zorgen voor voldoende inkomen. Er zijn veel studies verricht naar welke aspecten van werk bevorderlijk of juist hinderlijk zijn voor combinatie van werk en gezin. Deze studies

Noise, neoliberalism and Iain Sinclair

NARCIS (Netherlands)

Martin, N.

2012-01-01

Niall Martin onderzocht het werk van de Britse schrijver en filmmaker Iain Sinclair. Hij stelt dat het concept van ruis (noise), voortkomend uit de informatietheorie, een verhelderend kader biedt voor onderzoek naar het werk van Sinclair. Sinclair beschreef uitvoerig hoe Londen veranderde van

National Biocontainment Training Center

Science.gov (United States)

2015-02-01

BSL3 didactic BSL3 practical 1 1 Central Public Health Laboratory Ministry of Health and Population, Cairo, Egypt World Health Organization...courses taken. As expected the number of trainees follows the normal biosafety level pyramid with a large amount of BSL-2 trainees and then fewer as the...Distribution of trainees based on the courses taken. As expected the number of trainees follows the normal biosafety level pyramid with a large

Behavior of lactobacilli isolated from fermented slurry (ben-saalga in gnotobiotic rats.

Directory of Open Access Journals (Sweden)

Williams Turpin

Full Text Available Most bacterial strains, which have been studied so far for their probiotic functions, are extensively used by manufacturers in developed countries. In our work, we sought to study a mix (called BSL comprising three strains belonging to Lactobacillus fermentum, L. paraplantarum and L. salivarius, that were isolated from a traditional African pearl millet based fermented slurry. Our objective was to study this BSL cocktail in gnotobiotic rats, to evaluate their survival and their behavior in the digestive tract conditions. After a single oral inoculation of germfree rats with BSL, the species established stably in the digestive tract with the following hierarchy of abundance: L. salivarius> L. plantarum> L. fermentum. BSL cocktail was metabolically active since it produced 50 mM lactate and it expressed genes involved in binding mechanism in the caecum. Furthermore, the global morphology of the colon epithelium was not disturbed by the BSL cocktail. BSL cocktail did not modify mucus content and host mucus-related genes (MUC1, MUC2, MUC3 or resistin-like molecule β. The cocktail of lactobacilli enhanced the proliferating cell nuclear antigen (PCNA at a level comparable to what was observed in conventional rats. PCNA was involved in proliferation and DNA repair, but the presence of the cocktail did not provoke proliferative events (with Ki67 as indicator, so we suppose BSL may help gut preservation. This work is the first step towards the selection of strains that are derived from traditional fermented food to formulate new probiotic mixture.

P J Hoedemaker: 'Wat ék bedoel, is die behoud van die kerk'

African Journals Online (AJOL)

Philippus Jacobus Hoedemaker, asoek die werk van W Balke (1985), Gunning en. Hoedemaker: Samen op weg. Gedurende 1989 het daar ook 'n wye reeks tydskrif- artikels oer Hoedemaker verskyn. Daarbenewens het 'n omvattende werk oor. Hoedemaker onder redakteurskap van G Abma en J de Bruijn (1989) verskyn.

Het motorrijwiel : handboek voor motor- en scooterrijders, motor- en scootermonteurs en -technici

NARCIS (Netherlands)

Seyffardt, A.L.W.

1961-01-01

INHOUD: 1. De werking van de motor ; 2. De hoofddelen van de motor ; 3. De kleppen en de klepbeweging ; 4. Balancering, de meercilinder motor ; 5. Bijzonderheden over de werking ; 6. De carburateur ; 7. De smering van de motor ; 8. De tweetaktmotor ; 9. De elektrische installatie ; 10. De

Displacement along extensive deformation zones at the two SKB sites: Forsmark and Laxemar

International Nuclear Information System (INIS)

Beckholmen, Monica; Tiren, Sven A.

2010-12-01

The Fennoscandian shield, a part of the East European Craton, is distinguished by the exposed bedrock which is mainly composed of Precambrian metamorphic and igneous rocks. Large parts of the ground surface closely coincides with a late Precambrian denudation surface; the sub-Cambrian peneplain. Palaeozoic and younger sediments were deposited on the peneplain but these sediments have been removed from most areas that now form the mainland of Sweden and Finland and there are just a few remnants left. In the Baltic Sea, located in large-scale depressions on the boundary of in the Fennoscandian Shield/ in the East European Craton/, the Precambrian bedrock is still in large parts covered by Palaeozoic sediments. The Palaeozoic sedimentary rocks, as they are well bedded, may form a memory of the late Palaeozoic and younger tectonic events in the underlying basement rocks. Such data are used here to complement the structural observations made at sites located on the mainland, giving information on displacement along faults. Significant for the Baltic Sea are faults oriented in N-S that appear as segments, displaced relative to each other. Other structures are oriented in E-W, NE-SW and NW-SE. The SKB Forsmark site is located in a relatively flat coastal area within the sub-Cambrian peneplain. The sea area at the Forsmark site has a more accentuated relief than what is found on the mainland, for example, a furrow along the western side of the N-S oriented island Graesoe northeast of Forsmark (below 30m b.s.l. and locally more than 50m lower than Graesoe) and the deep between Aaland and Sweden (301m b.s.l.) about 100km east-southeast of Forsmark. In the Forsmark-site area two sets of structures interfere: a WNWESE trending set with relatively straight faults along the north coast of Uppland and a NNW-SSE to N-S trending set, slightly curved, along the (north)east coast of Uppland. The Forsmark site is located in an elevated WNW trending lath-shaped rock block outlined by

Displacement along extensive deformation zones at the two SKB sites: Forsmark and Laxemar

Energy Technology Data Exchange (ETDEWEB)

Beckholmen, Monica; Tiren, Sven A. (GEOSIGMA AB (Sweden))

2010-12-15

The Fennoscandian shield, a part of the East European Craton, is distinguished by the exposed bedrock which is mainly composed of Precambrian metamorphic and igneous rocks. Large parts of the ground surface closely coincides with a late Precambrian denudation surface; the sub-Cambrian peneplain. Palaeozoic and younger sediments were deposited on the peneplain but these sediments have been removed from most areas that now form the mainland of Sweden and Finland and there are just a few remnants left. In the Baltic Sea, located in large-scale depressions on the boundary of in the Fennoscandian Shield/ in the East European Craton/, the Precambrian bedrock is still in large parts covered by Palaeozoic sediments. The Palaeozoic sedimentary rocks, as they are well bedded, may form a memory of the late Palaeozoic and younger tectonic events in the underlying basement rocks. Such data are used here to complement the structural observations made at sites located on the mainland, giving information on displacement along faults. Significant for the Baltic Sea are faults oriented in N-S that appear as segments, displaced relative to each other. Other structures are oriented in E-W, NE-SW and NW-SE. The SKB Forsmark site is located in a relatively flat coastal area within the sub-Cambrian peneplain. The sea area at the Forsmark site has a more accentuated relief than what is found on the mainland, for example, a furrow along the western side of the N-S oriented island Graesoe northeast of Forsmark (below 30m b.s.l. and locally more than 50m lower than Graesoe) and the deep between Aaland and Sweden (301m b.s.l.) about 100km east-southeast of Forsmark. In the Forsmark-site area two sets of structures interfere: a WNWESE trending set with relatively straight faults along the north coast of Uppland and a NNW-SSE to N-S trending set, slightly curved, along the (north)east coast of Uppland. The Forsmark site is located in an elevated WNW trending lath-shaped rock block outlined by

Invloed van minerale olie op de bestrijding van Phytophthora infestans in pootaardappelen

NARCIS (Netherlands)

Spits, H.G.; Bus, C.B.

2003-01-01

De invloed van toevoeging van olie aan een fungicide op de werking van het fungicide is afhankelijk van het gebruikte fungicide. Gezamenlijk spuiten van olie en Aviso DF, Curzate M en mogelijk ook Acrobat, verhoogt de curatieve werking van deze fungiciden. Gezamenlijk spuiten van olie en Aviso DF,

Actuele en opkomende VGW-problemen in de gezondheidszorg, waaronder thuis- en gemeenschapszorg : Europese waarnemingspost voor risico's

NARCIS (Netherlands)

Jong, T. de; Bos, E.; Pawlowska-Cyprysiak, K.; Hildt-Ciupińska, K.; Malińska, M.; Nicolescu, G.; Trifu, A.

2014-01-01

Deze samenvatting biedt een overzicht van de actuele en opkomende problemen qua veiligheid en gezondheid op het werk (VGW) voor werknemers in de gezondheids- en maatschappelijke zorg en laat zien wat de gevolgen hiervan zijn voor hun veiligheid en gezondheid op het werk en voor de kwaliteit van de

Sharing is Caring

DEFF Research Database (Denmark)

Sanderhoff, Merete

2015-01-01

70 Jahre nach dem Tod eines Urhebers werden dessen Werke zu öffentlichem geistigem Eigentum, sie sind gemeinfrei und gehören somit dem Publikum. Damit sind nicht nur mittelalterliche Texte, sondern auch Bücher und Werke aus dem 20. Jahrhundert frei. Die Digitalisierung hat dem Umgang mit diesen...

Anfangen, sich die Welt anders vorzustellen

Directory of Open Access Journals (Sweden)

Sabine Fuchs

2006-11-01

Full Text Available Der Sammelband Butler Matters bezeugt Judith Butlers außerordentliche Bedeutung für feministische und queere Studien und Forschung. In elf Beiträgen wird Butlers (frühes Werk von Gender Trouble und Bodies That Matter über Excitable Speech bis zu The Psychic Life of Power betrachtet und sein weit reichender Einfluss quer durch die wissenschaftlichen Disziplinen nachgewiesen. Dargestellt werden auch die kontroverse Rezeption von Butlers Werk sowie die politischen Wirkungen von Butlers Denken. Besonders anregend ist ein zweiteiliges Interview mit Judith Butler, in dem sie auf ein breites Spektrum von Fragen eingeht, die auch wichtige Themen ihrer aktuelleren Werke betreffen.

PET quantification with a histogram derived total activity metric: Superior quantitative consistency compared to total lesion glycolysis with absolute or relative SUV thresholds in phantoms and lung cancer patients

International Nuclear Information System (INIS)

Burger, Irene A.; Vargas, Hebert Alberto; Apte, Aditya; Beattie, Bradley J.; Humm, John L.; Gonen, Mithat; Larson, Steven M.; Ross Schmidtlein, C.

2014-01-01

Introduction: The increasing use of molecular imaging probes as biomarkers in oncology emphasizes the need for robust and stable methods for quantifying tracer uptake in PET imaging. The primary motivation for this research was to find an accurate method to quantify the total tumor uptake. Therefore we developed a histogram-based method to calculate the background subtracted lesion (BSL) activity and validated BSL by comparing the quantitative consistency with the total lesion glycolysis (TLG) in phantom and patient studies. Methods: A thorax phantom and a PET-ACR quality assurance phantom were scanned with increasing FDG concentrations. Volumes of interest (VOIs) were placed over each chamber. TLG was calculated with a fixed threshold at SUV 2.5 (TLG 2.5 ) and a relative threshold at 42% of SUV max (TLG 42% ). The histogram for each VOI was built and BSL was calculated. Comparison with the total injected FDG activity (TIA) was performed using concordance correlation coefficients (CCC) and the slope (a). Fifty consecutive patients with FDG-avid lung tumors were selected under an IRB waiver. TLG 42% , TLG 2.5 and BSL were compared to the reference standard calculating CCC and the slope. Results: In both phantoms, the CCC for lesions with a TIA ≤ 50 ml*SUV between TIA and BSL was higher and the slope closer to 1 (CCC = 0.933, a = 1.189), than for TLG 42% (CCC = 0.350, a = 0.731) or TLG 2.5 (CCC = 0.761, a = 0.727). In 50 lung lesions BSL had a slope closer to 1 compared to the reference activity than TLG 42% (a = 1.084 vs 0.618 – for high activity lesions) and also closer to 1 than TLG 2.5 (a = 1.117 vs 0.548 – for low activity lesions). Conclusion: The histogram based BSL correlated better with TIA in both phantom studies than TLG 2.5 or TLG 42% . Also in lung tumors, the BSL activity is overall more accurate in quantifying the lesion activity compared to the two most commonly applied TLG quantification methods

A Diagonal-Steering-Based Binaural Beamforming Algorithm Incorporating a Diagonal Speech Localizer for Persons With Bilateral Hearing Impairment.

Science.gov (United States)

Lee, Jun Chang; Nam, Kyoung Won; Jang, Dong Pyo; Kim, In Young

2015-12-01

Previously suggested diagonal-steering algorithms for binaural hearing support devices have commonly assumed that the direction of the speech signal is known in advance, which is not always the case in many real circumstances. In this study, a new diagonal-steering-based binaural speech localization (BSL) algorithm is proposed, and the performances of the BSL algorithm and the binaural beamforming algorithm, which integrates the BSL and diagonal-steering algorithms, were evaluated using actual speech-in-noise signals in several simulated listening scenarios. Testing sounds were recorded in a KEMAR mannequin setup and two objective indices, improvements in signal-to-noise ratio (SNRi ) and segmental SNR (segSNRi ), were utilized for performance evaluation. Experimental results demonstrated that the accuracy of the BSL was in the 90-100% range when input SNR was -10 to +5 dB range. The average differences between the γ-adjusted and γ-fixed diagonal-steering algorithms (for -15 to +5 dB input SNR) in the talking in the restaurant scenario were 0.203-0.937 dB for SNRi and 0.052-0.437 dB for segSNRi , and in the listening while car driving scenario, the differences were 0.387-0.835 dB for SNRi and 0.259-1.175 dB for segSNRi . In addition, the average difference between the BSL-turned-on and the BSL-turned-off cases for the binaural beamforming algorithm in the listening while car driving scenario was 1.631-4.246 dB for SNRi and 0.574-2.784 dB for segSNRi . In all testing conditions, the γ-adjusted diagonal-steering and BSL algorithm improved the values of the indices more than the conventional algorithms. The binaural beamforming algorithm, which integrates the proposed BSL and diagonal-steering algorithm, is expected to improve the performance of the binaural hearing support devices in noisy situations. Copyright © 2015 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

34 Resensie Fourie WEB 03.pmd

African Journals Online (AJOL)

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In 2009 verskyn Louise Viljoen se bundel opstelle, Ons ongehoorde soort: Beskouings oor die werk van Antjie Krog. Dié publikasie getuig duidelik van 'n navorser wat 'n lewenslange belangstelling in die werk van een digter noukeurig uitgebou het tot 'n formidabele kritiese beskouing oor een van Afrikaans se veelsydigste ...

Immobilization of Bacillus subtilis lipase on a Cu-BTC based hierarchically porous metal-organic framework material: a biocatalyst for esterification.

Science.gov (United States)

Cao, Yu; Wu, Zhuofu; Wang, Tao; Xiao, Yu; Huo, Qisheng; Liu, Yunling

2016-04-28

Bacillus subtilis lipase (BSL2) has been successfully immobilized into a Cu-BTC based hierarchically porous metal-organic framework material for the first time. The Cu-BTC hierarchically porous MOF material with large mesopore apertures is prepared conveniently by using a template-free strategy under mild conditions. The immobilized BSL2 presents high enzymatic activity and perfect reusability during the esterification reaction. After 10 cycles, the immobilized BSL2 still exhibits 90.7% of its initial enzymatic activity and 99.6% of its initial conversion.

On the interpretation of millennium-scale level variations of the Black Sea during the first quarter of the Holocene

Science.gov (United States)

Kislov, Alexander

2016-04-01

Introduction. During the first quarter of the Holocene, the Black Sea (BS) experienced large changes: amid the gradually rising water surface, Black Sea level (BSL) fluctuations occurred. We calculated based on records (e.g., Balabanov, 2007) that the standard deviation is ˜3.5 ÷ 5 m. Their typical duration was ˜1000 years. Time of occurrence of positive and negative anomalies of the BS is different in different reconstructions. The source of these discrepancies could be tectonically induced vertical motions. Before ˜7 ka BP the BSL was higher than the level of the World Ocean. The rising BS spilled over a rocky sill at the Bosphorus (Chepalyga, 2007). It is clear that if the water discharge were quite large, the long-term BSL anomalies could not be. This study focuses on the quantification of this concept. Methodology. I use the equation of the water balance of the BS in term of the annual averaged level anomalies. Time scales of the BSL fluctuations were determined based on the BS basin morphology and averaged volumes of rivers runoff and water discharge via the Bosphorus Sill. The short-term (1-2 year) contribution (like random white noise) to level changes are due to variations of river runoff and precipitation mines evaporation. From this perspective, the water balance equation is represented as a stochastic Langevin equation (Kislov, 2015). In another case, the BSL anomaly could be destructed due to relation "BSL anomaly - value of water discharge via the Bosphorus Sill" which acts as a negative feedback. Results. To quantify the parameters, I use the present day information about hydrological regime of the BS. It should not lead to serious errors, because the first and last quarters of the Holocene exhibit similarity in their hydroclimatic regimes (Panin, Matlakhova, 2014). As well, the paleohydrological data about dynamics of the Dnieper River runoff was used (Swetc, 1978). It was found that the time scale of the BSL fluctuations due to water discharge

Resensies/Reviews 294 book without feeling overwhelmed by the ...

African Journals Online (AJOL)

uitgegee word, is om verskeie redes heel gepas. Eerstens is die boek 'n goeie uitdrukking van Brümmer se oevre en werk. Hy beklemtoon deur- gaans hierin die belangrikheid daarvan dat ons met geen ewige, tydlose, gestolde, geslote waarheid werk nie, maar dat ons in 'n dinamiese proses onderweg is om voortdurend ...

Redaksioneel

African Journals Online (AJOL)

LouwnaVanHeerden

daar narratiewe paradigmas na vore gekom het vir die lees van vertel- tekste. Die kritiese paradigma wat ook bekend staan as die meganiese paradigma, opereer deur 'n werk in dele op te breek, kousale en gene- tiese oorspronge daarvan te probeer vasstel en die geskiedenis van die vorming van die werk te probeer ...

Anomalous fading of the TL, Blue-SL and IR-SL signals of fluorapatite

International Nuclear Information System (INIS)

Tsirliganis, N.; Polymeris, G.; Loukou, Z.; Kitis, G.

2006-01-01

The thermoluminescence (TL), blue stimulated luminescence (BSL) and infrared stimulated luminescence (IRSL) signals of fluorapatite (originating from Durango, Mexico) were measured and found to exhibit strong anomalous fading (AF). The experimentally obtained OSL and IRSL decay curves were transformed into pseudo-linear modulated (pseudo-LM) decay curves. The resulting glow-curve shaped pseudo-LM decay curves were analyzed using a deconvolution analysis, similar to the one used for the glow-curve deconvolution (GCD) of TL glow-curves. It was found that the pseudo-LM OSL and IRSL decay curves consist of two components named fast and slow, respectively, and their individual contribution was estimated. The AF of the remnant TL, BSL and IRSL as a function of the storage time was fitted using the tunneling model equations and the fading rate g, in terms of percentage per decade was evaluated. According to the obtained g values, the AF of the BSL and IRSL is stronger than that of the TL. The AF of the fast component of BSL and IRSL is almost the same. The AF of the slow component of IRSL is, by approximately a factor of 2, stronger than that of the BSL

Development of Geography and Geology Terminology in British Sign Language

Science.gov (United States)

Meara, Rhian; Cameron, Audrey; Quinn, Gary; O'Neill, Rachel

2016-04-01

The BSL Glossary Project, run by the Scottish Sensory Centre at the University of Edinburgh focuses on developing scientific terminology in British Sign Language for use in the primary, secondary and tertiary education of deaf and hard of hearing students within the UK. Thus far, the project has developed 850 new signs and definitions covering Chemistry, Physics, Biology, Astronomy and Mathematics. The project has also translated examinations into BSL for students across Scotland. The current phase of the project has focused on developing terminology for Geography and Geology subjects. More than 189 new signs have been developed in these subjects including weather, rivers, maps, natural hazards and Geographical Information Systems. The signs were developed by a focus group with expertise in Geography and Geology, Chemistry, Ecology, BSL Linguistics and Deaf Education all of whom are deaf fluent BSL users.

Predicate Structures, Gesture, and Simultaneity in the Representation of Action in British Sign Language: Evidence From Deaf Children and Adults

Science.gov (United States)

Cormier, Kearsy

2013-01-01

British Sign Language (BSL) signers use a variety of structures, such as constructed action (CA), depicting constructions (DCs), or lexical verbs, to represent action and other verbal meanings. This study examines the use of these verbal predicate structures and their gestural counterparts, both separately and simultaneously, in narratives by deaf children with various levels of exposure to BSL (ages 5;1 to 7;5) and deaf adult native BSL signers. Results reveal that all groups used the same types of predicative structures, including children with minimal BSL exposure. However, adults used CA, DCs, and/or lexical signs simultaneously more frequently than children. These results suggest that simultaneous use of CA with lexical and depicting predicates is more complex than the use of these predicate structures alone and thus may take deaf children more time to master. PMID:23670881

Practical biosafety in the tuberculosis laboratory: containment at the source is what truly counts

NARCIS (Netherlands)

Soolingen, D.; Wisselink, H.J.; Lumb, R.; Anthony, R.; Zanden, van der A.; Gilpin, C.

2014-01-01

In industrialised countries, sufficient resources for establishing and maintaining fully equipped biosafety level 3 (BSL-3) laboratories according to international standards are generally available. BSL-3 laboratories are designed to provide several layers of containment to protect the laboratory

as by die huisbesoek. HP WOLMARANS. PROF. DR. SP ...

African Journals Online (AJOL)

Test

van 'n evangeüedienaar wat alles fei! gehad het vir die werk en werk kring waartoe God hom geroep het. Hy is dan ook werklik die eerste grondlegger van die gemeente in Zoutpansberg en die man wat dit opgewerk het. Die geskiedenis van Hofmeyer is die geskiedenis van die kerk- vereniging en die redes waarom die ...

A catalytically and genetically optimized β-lactamase-matrix based assay for sensitive, specific, and higher throughput analysis of native henipavirus entry characteristics

Directory of Open Access Journals (Sweden)

Holbrook Michael R

2009-07-01

Full Text Available Abstract Nipah virus (NiV and Hendra virus (HeV are the only paramyxoviruses requiring Biosafety Level 4 (BSL-4 containment. Thus, study of henipavirus entry at less than BSL-4 conditions necessitates the use of cell-cell fusion or pseudotyped reporter virus assays. Yet, these surrogate assays may not fully emulate the biological properties unique to the virus being studied. Thus, we developed a henipaviral entry assay based on a β-lactamase-Nipah Matrix (βla-M fusion protein. We first codon-optimized the bacterial βla and the NiV-M genes to ensure efficient expression in mammalian cells. The βla-M construct was able to bud and form virus-like particles (VLPs that morphologically resembled paramyxoviruses. βla-M efficiently incorporated both NiV and HeV fusion and attachment glycoproteins. Entry of these VLPs was detected by cytosolic delivery of βla-M, resulting in enzymatic and fluorescent conversion of the pre-loaded CCF2-AM substrate. Soluble henipavirus receptors (ephrinB2 or antibodies against the F and/or G proteins blocked VLP entry. Additionally, a Y105W mutation engineered into the catalytic site of βla increased the sensitivity of our βla-M based infection assays by 2-fold. In toto, these methods will provide a more biologically relevant assay for studying henipavirus entry at less than BSL-4 conditions.

Baltic Scandinavian Lines - Tallinki konkurent, kes end konkurendiks ei nimeta / Margo Heinla ; interv. Mart Riikoja

Index Scriptorium Estoniae

Heinla, Margo

2005-01-01

BSL-i tegevjuht kinnitab, et Tallink ei ole nende jaoks konkurent, kuna tegevusalad on nii erinevad. BSL-i ainus laev Via Mare on orienteeritud kaubavedudele Paldiskist Lõuna-Rootsi Västerviki ja Kapellskäri. Vaba ruumi korral veetakse üle ka sõiduautosid

77 FR 6971 - Establishment of User Fees for Filovirus Testing of Nonhuman Primate Liver Samples

Science.gov (United States)

2012-02-10

... Director on March 15, 1990, that they must comply with specific isolation and quarantine standards under 42... biosafety level 4 laboratory (BSL-4). A BSL-4 laboratory is also required during part of the testing... and supervisory costs; and the costs of enforcement, collection, research, establishment of standards...

COPD en werk.

NARCIS (Netherlands)

Houtum, L. van; Heijmans, M.

2010-01-01

Drie van de vijf mensen met chronisch obstructieve longziekte werkt niet. In veel gevallen is hun longziekte hiervan de oorzaak, zo blijkt uit de Astma-/COPD-monitor. In Nederland hebben 320.000 mensen de diagnose chronisch obstructieve longziekte (COPD). Daarnaast zijn er nog eens zo’n 300.000

‘Das politische Welträtsel’: Ernst Haeckel en het Duitse liberalisme 1859-1900

Directory of Open Access Journals (Sweden)

Daan Wegener

2011-09-01

Full Text Available Het werk van de evolutionair-morfoloog en wetenschapspopularisator Ernst Haeckel is uiterst omstreden. Zijn sociaaldarwinisme is na de Tweede Wereldoorlog om begrijpelijke redenen in een kwaad daglicht komen te staan. De meest expliciete veroordeling van Haeckel is waarschijnlijk Daniel Gasmans The Scientific Origins of National Socialism in Ernst Haeckel. Inmiddels hebben wetenschapshistorici het eenzijdig negatieve beeld genuanceerd. Volgens de standaardkritiek is het anachronistisch om latere ontwikkelingen terug te projecteren op het werk van Haeckel. Zo ziet Robert Richards in Haeckel geen voorloper van het nazisme, maar een late vertegenwoordiger van een Duitse romantische traditie, die teruggaat op Alexander von Humboldt en Goethe. Met andere woorden Richards is meer geïnteresseerd in de intellectuele achtergronden, dan in de politieke en culturele werking van Haeckels denken.

U.S. Ebola Treatment Center Clinical Laboratory Support.

Science.gov (United States)

Jelden, Katelyn C; Iwen, Peter C; Herstein, Jocelyn J; Biddinger, Paul D; Kraft, Colleen S; Saiman, Lisa; Smith, Philip W; Hewlett, Angela L; Gibbs, Shawn G; Lowe, John J

2016-04-01

Fifty-five hospitals in the United States have been designated Ebola treatment centers (ETCs) by their state and local health authorities. Designated ETCs must have appropriate plans to manage a patient with confirmed Ebola virus disease (EVD) for the full duration of illness and must have these plans assessed through a CDC site visit conducted by an interdisciplinary team of subject matter experts. This study determined the clinical laboratory capabilities of these ETCs. ETCs were electronically surveyed on clinical laboratory characteristics. Survey responses were returned from 47 ETCs (85%). Forty-one (87%) of the ETCs planned to provide some laboratory support (e.g., point-of-care [POC] testing) within the room of the isolated patient. Forty-four (94%) ETCs indicated that their hospital would also provide clinical laboratory support for patient care. Twenty-two (50%) of these ETC clinical laboratories had biosafety level 3 (BSL-3) containment. Of all respondents, 34 (72%) were supported by their jurisdictional public health laboratory (PHL), all of which had available BSL-3 laboratories. Overall, 40 of 44 (91%) ETCs reported BSL-3 laboratory support via their clinical laboratory and/or PHL. This survey provided a snapshot of the laboratory support for designated U.S. ETCs. ETCs have approached high-level isolation critical care with laboratory support in close proximity to the patient room and by distributing laboratory support among laboratory resources. Experts might review safety considerations for these laboratory testing/diagnostic activities that are novel in the context of biocontainment care. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Characterization of Bifunctional Spin Labels for Investigating the Structural and Dynamic Properties of Membrane Proteins Using EPR Spectroscopy.

Science.gov (United States)

Sahu, Indra D; Craig, Andrew F; Dunagum, Megan M; McCarrick, Robert M; Lorigan, Gary A

2017-10-05

Site-directed spin labeling (SDSL) coupled with electron paramagnetic resonance (EPR) spectroscopy is a very powerful technique to study structural and dynamic properties of membrane proteins. The most widely used spin label is methanthiosulfonate (MTSL). However, the flexibility of this spin label introduces greater uncertainties in EPR measurements obtained for determining structures, side-chain dynamics, and backbone motion of membrane protein systems. Recently, a newer bifunctional spin label (BSL), 3,4-bis(methanethiosulfonylmethyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxy, has been introduced to overcome the dynamic limitations associated with the MTSL spin label and has been invaluable in determining protein backbone dynamics and inter-residue distances due to its restricted internal motion and fewer size restrictions. While BSL has been successful in providing more accurate information about the structure and dynamics of several proteins, a detailed characterization of the spin label is still lacking. In this study, we characterized BSLs by performing CW-EPR spectral line shape analysis as a function of temperature on spin-labeled sites inside and outside of the membrane for the integral membrane protein KCNE1 in POPC/POPG lipid bilayers and POPC/POPG lipodisq nanoparticles. The experimental data revealed a powder pattern spectral line shape for all of the KCNE1-BSL samples at 296 K, suggesting the motion of BSLs approaches the rigid limit regime for these series of samples. BSLs were further utilized to report for the first time the distance measurement between two BSLs attached on an integral membrane protein KCNE1 in POPC/POPG lipid bilayers at room temperature using dipolar line broadening CW-EPR spectroscopy. The CW dipolar line broadening EPR data revealed a 15 ± 2 Å distance between doubly attached BSLs on KCNE1 (53/57-63/67) which is consistent with molecular dynamics modeling and the solution NMR structure of KCNE1 which yielded a

77 FR 7109 - Establishment of User Fees for Filovirus Testing of Nonhuman Primate Liver Samples

Science.gov (United States)

2012-02-10

... quarantine standards under 42 CFR part 71 for continued registration as an importer of NHPs (2). On March 23... reagents requires a biosafety level 4 laboratory (BSL-4). A BSL- 4 laboratory is also required during part..., establishment of standards, and regulation. Full costs are determined based on the best available records of the...

MALDI-TOF mass spectrometry and high-consequence bacteria: safety and stability of biothreat bacterial sample testing in clinical diagnostic laboratories.

Science.gov (United States)

Tracz, Dobryan M; Tober, Ashley D; Antonation, Kym S; Corbett, Cindi R

2018-03-01

We considered the application of MALDI-TOF mass spectrometry for BSL-3 bacterial diagnostics, with a focus on the biosafety of live-culture direct-colony testing and the stability of stored extracts. Biosafety level 2 (BSL-2) bacterial species were used as surrogates for BSL-3 high-consequence pathogens in all live-culture MALDI-TOF experiments. Viable BSL-2 bacteria were isolated from MALDI-TOF mass spectrometry target plates after 'direct-colony' and 'on-plate' extraction testing, suggesting that the matrix chemicals alone cannot be considered sufficient to inactivate bacterial culture and spores in all samples. Sampling of the instrument interior after direct-colony analysis did not recover viable organisms, suggesting that any potential risks to the laboratory technician are associated with preparation of the MALDI-TOF target plate before or after testing. Secondly, a long-term stability study (3 years) of stored MALDI-TOF extracts showed that match scores can decrease below the threshold for reliable species identification (<1.7), which has implications for proficiency test panel item storage and distribution.

Mission Command During the War of Movement in World War I Initiative and Synchronization of the German Right Wing in August and Early September 1914

Science.gov (United States)

2014-12-04

höheren Truppenführer vom 24. Juni 1869,” in Moltkes Militärische Werke, Zweiter Theil, Die Tätigkeit als Chef des Generalstabs im Frieden, ed...the command structure with respect to the question of whether the individual instances reflect professional judgment given the information available...22.6.1866” in Moltkes Militärische Werke, Zweiter Theil, Die Tätigkeit als Chef des Generalstabs im Frieden, ed. Preußischer Generalstab (Berlin

Practical biosafety in the tuberculosis laboratory: containment at the source is what truly counts.

Science.gov (United States)

van Soolingen, D; Wisselink, H J; Lumb, R; Anthony, R; van der Zanden, A; Gilpin, C

2014-08-01

In industrialised countries, sufficient resources for establishing and maintaining fully equipped biosafety level 3 (BSL-3) laboratories according to international standards are generally available. BSL-3 laboratories are designed to provide several layers of containment to protect the laboratory worker as well as the outside environment and community from risk of exposure in case of local contamination. However, such facilities are scarce in high-burden settings, primarily due to the high financial burden and complexity of the initial construction and/or regular maintenance. Measures to prevent unintended exposure to Mycobacterium tuberculosis during laboratory manipulation of specimens and cultures is the first, and by far the most important, aspect of containment. This paper focuses on the need for risk containment at source. Assuming that in many settings the establishment of BSL-3 laboratories with all the required features is not achievable, this paper also discusses the minimum requirements necessary to mitigate risks associated with particular laboratory procedures. The term 'TB containment laboratory' is used throughout this paper to describe the minimum requirements for a laboratory suitable for high-risk procedures. The TB containment laboratory has many, but not all, of the features of a BSL-3 laboratory.

Certificering in het Hoger Onderwijs: De medewerking van professionals aan kwaliteitscontrole

Directory of Open Access Journals (Sweden)

Everard van Kemenade

2010-06-01

Dit artikel presenteert de resultaten van een onderzoek naar de bereidheid van professionals in Hogescholen in Nederland en Vlaanderen om mee te werken aan het accreditatieproces. Betoogd wordt dat accreditatie eigenlijk een vorm van certificering is. Conclusies zijn dat professionals loyaal zijn naar hun organisatie en bereid zijn verantwoording af te leggen. De nadruk in de certificering zou dan echter moeten liggen op de inhoud van het werk en de beoordeling zou moeten worden gedaan door vakgenoten (peer review. Er treden meer problemen op bij het certificeringproces, als het management de certificering onvoldoende ondersteunt of als de interne kwaliteitszorg onvoldoende op orde is. Er is een risico dat er window dressing optreedt. Uiteindelijk leidt dat tot de conclusie dat controle (door middel van bijvoorbeeld ISO of HKZcertificering gescheiden zou moeten worden van verbetering. Er zijn voldoende overeenkomsten tussen hoger onderwijs en maatschappelijk werk om te bezien of de resultaten ook gelden voor maatschappelijk werk.

First language acquisition differs from second language acquisition in prelingually deaf signers: evidence from sensitivity to grammaticality judgement in British Sign Language.

Science.gov (United States)

Cormier, Kearsy; Schembri, Adam; Vinson, David; Orfanidou, Eleni

2012-07-01

Age of acquisition (AoA) effects have been used to support the notion of a critical period for first language acquisition. In this study, we examine AoA effects in deaf British Sign Language (BSL) users via a grammaticality judgment task. When English reading performance and nonverbal IQ are factored out, results show that accuracy of grammaticality judgement decreases as AoA increases, until around age 8, thus showing the unique effect of AoA on grammatical judgement in early learners. No such effects were found in those who acquired BSL after age 8. These late learners appear to have first language proficiency in English instead, which may have been used to scaffold learning of BSL as a second language later in life. Copyright © 2012 Elsevier B.V. All rights reserved.

Insight into a Pedagogical Sketchbook. Life and work of Eva Eyquem

OpenAIRE

Richter, Sabine

2016-01-01

Die vorliegende Arbeit dokumentiert und kontextualisiert das Werk der französischen Kunstpädagogin und ehemaligen Itten-Schülerin Eva Eyquem, geb. Plaut (1915-2009). Es ist meine Absicht, ihr Werk für Forschung und Lehre zugänglich zu machen und für einen kunstpädagogischen Diskurs zu öffnen, der sich mit Positionen in der Nachfolge der Bauhaus-Pädagogik befasst. Meine Arbeit ist in zwei Teile gegliedert. Sie umfasst eine Monografie zu Eva Eyquem, sowie eine fachwissenschaftliche Reflexion, i...

Casuïstiek van sociaal werkers, schatkamer of trompe-l'oeil?

Directory of Open Access Journals (Sweden)

Hilde Vlaeminck

2005-12-01

Full Text Available Casuïstiek is van oudsher een beproefd leermiddel in de geneeskunde en de moraalwetenschappen maar ook in het maatschappelijk werk. De oudste methodiek in het maatschappelijk werk – niet toevallig Social Casework genoemd – bestudeerde zorgvuldig praktijkgevallen, verteld door maatschappelijk werkers van het eerste uur (Kamphuis, 1971. Men trachtte toen de opgemerkte fenomenen en vastgestelde effecten te beschrijven, te verklaren en te verantwoorden met behulp van beschikbare wetenschappelijke kennis. Een eerste, opmerkelijke stap in een lang proces van professionalisering en kennisontwikkeling.

Extreme Ultraviolet Explorer Bright Source List

Science.gov (United States)

Malina, Roger F.; Marshall, Herman L.; Antia, Behram; Christian, Carol A.; Dobson, Carl A.; Finley, David S.; Fruscione, Antonella; Girouard, Forrest R.; Hawkins, Isabel; Jelinsky, Patrick

1994-01-01

Initial results from the analysis of the Extreme Ultraviolet Explorer (EUVE) all-sky survey (58-740 A) and deep survey (67-364 A) are presented through the EUVE Bright Source List (BSL). The BSL contains 356 confirmed extreme ultraviolet (EUV) point sources with supporting information, including positions, observed EUV count rates, and the identification of possible optical counterparts. One-hundred twenty-six sources have been detected longward of 200 A.

Gesammelte Werke / Collected Works

Science.gov (United States)

Schwarzschild, Karl; Voigt, Hans-Heinrich

Der bekannte Astronom Karl Schwarzschild (1873-1916) gilt als der Begründer der Astrophysik und als hervorragender Forscher mit einer erstaunlichen Bandbreite seiner Interessen. Arbeiten zur Himmelsmechanik, Elektrodynamik und Relativitätstheorie weisen ihn als vorzüglichen Mathematiker und Physiker auf der Höhe seiner Zeit aus. Untersuchungen zur Photographischen Photometrie, Optik und Spektroskopie zeigen den versierten Beobachter, der sein Meßinstrumentarium beherrscht, und schließlich arbeitete Schwarzschild als Astrophysiker an Sternatmosphären, Kometen, Struktur und Dynamik von Sternsystemen. Die in seinem kurzen Leben entstandene Fülle an wissenschaftlichen Arbeiten ist in drei Bänden der Gesamtausgabe gesammelt, ergänzt durch biographisches Material, Annotationen von Fachleuten und einen Essay des Nobelpreisträgers S. Chandrasekhar. The well-known astronomer Karl Schwarzschild (1873-1916) is regarded as the founder of astrophysics and as an exceptionally talented researcher whose interests spanned a remarkably broad spectrum. His work on celestial mechanics, electrodynamics, and relativity theory demonstrates his great abilities as a mathematician and physicist who significantly influenced the science of his times. His investigations of photographic photometry, optics, and spectroscopy display his strengths as an observer who knew his instruments. But above all Schwarzschild pursued questions of astrophysics, addressing in particular stellar atmospheres, comets, and the structure and dynamics of stellar systems. The host of scientific works that he authored in his short life is now collected in the form of this three-volume complete works; it is supplemented by biographical material, notes from some of todays experts, and an essay by the Nobel Laureate S. Chandrasekhar.

Beter aan het werk

NARCIS (Netherlands)

Gerda Jehoel-Gijsbers

2007-01-01

Jarenlang was Nederland koploper in Europa in het aantal gevallen van ziekteverzuim en arbeidsongeschiktheid. Om dit probleem tegen te gaan zijn in de afgelopen decennia veel beleidsmaatregelen ontwikkeld en vaak ook weer aangepast. Hebben deze maatregelen tot resultaat geleid? Is het

Werking bodemherbiciden soms overschat

NARCIS (Netherlands)

Zeeland, van M.G.

2007-01-01

De werkingsduur van Goltix en isoproturon wordt in de praktijk overschat, zo blijkt uit onderzoek. De duurwerking kan worden verlengd door vaker te bespuiten in lage dosering. Een verslag over bodemherbiciden en bodemeigenschappen

Biosurfactant production from Pseudomonas taiwanensis L1011 and its application in accelerating the chemical and biological decolorization of azo dyes.

Science.gov (United States)

Liu, Cong; You, Yanting; Zhao, Ruofei; Sun, Di; Zhang, Peng; Jiang, Jihong; Zhu, Aihua; Liu, Weijie

2017-11-01

Dye dispersion and the interaction efficiency between azoreductases and dye molecules are rate-limiting steps for the decolorization of azo dyes. In this study, a biosurfactant-producing strain, Pseudomonas taiwanensis L1011, was isolated from crude oil. To increase the yield of the biosurfactant BS-L1011 from P. taiwanensis L1011, culture conditions were optimized including temperature, initial pH, carbon source, nitrogen source and C/N ratio. A maximum yield of 1.12g/L of BS-L1011 was obtained using D-mannitol as carbon source and yeast extract/urea as compound nitrogen source with C/N ratio of 10/4, pH 7.0 and 28°C. BS-L1011 exhibited a low critical micelle concentration (CMC) of 10.5mg/L and was able to reduce the surface tension of water to 25.8±0.1 mN/m. BS-L1011 was stable over a wide range of temperatures, pH values and salt concentrations. The biosurfactant is reported for the first time to accelerate chemical decolorization of Congo red by sodium hypochlorite, and biological decolorization of Amaranth by Bacillus circulans BWL1061, thus showing a potential in the treatment of dyeing wastewater. Copyright © 2017 Elsevier Inc. All rights reserved.

Ein Nachkömmling Tristans : Warum hat Theodor Storm in seiner Novelle „Späte Rosen" Gottfried von Straßburgs „Tristan und Isolde" erwähnt?

OpenAIRE

田淵, 昌太

2010-01-01

Man hat bisher Theodor Storms Novelle „Späte Rosen" für ein Werk gehalten, das ein friedliches Familienleben beziehungweise das tägliche Zusammenleben eines Ehepaars schildert. Zum Beispiel hat Beate Charlotte Göhler in ihrer umfangreichen Storm-Biografie geschrieben, dass Theodor Storm mit diesem Werk seiner Frau Constanze eine Liebeserklärung machte („Ein Leben für die Graue Stadt" S.198). Wenn man diese Novelle nur oberflächlich liest, ist es eine mögliche Folge, dass man „Späte Rosen"...

Lexical Variation and Change in British Sign Language

Science.gov (United States)

Stamp, Rose; Schembri, Adam; Fenlon, Jordan; Rentelis, Ramas; Woll, Bencie; Cormier, Kearsy

2014-01-01

This paper presents results from a corpus-based study investigating lexical variation in BSL. An earlier study investigating variation in BSL numeral signs found that younger signers were using a decreasing variety of regionally distinct variants, suggesting that levelling may be taking place. Here, we report findings from a larger investigation looking at regional lexical variants for colours, countries, numbers and UK placenames elicited as part of the BSL Corpus Project. Age, school location and language background were significant predictors of lexical variation, with younger signers using a more levelled variety. This change appears to be happening faster in particular sub-groups of the deaf community (e.g., signers from hearing families). Also, we find that for the names of some UK cities, signers from outside the region use a different sign than those who live in the region. PMID:24759673

The Hausa Lexicographic Tradition

Directory of Open Access Journals (Sweden)

Roxana Ma Newman

2011-10-01

Full Text Available

Abstract: Hausa, a major language of West Africa, is one of the most widely studied languagesof Sub-Saharan Africa. It has a rich lexicographic tradition dating back some two centuries. Sincethe first major vocabulary published in 1843 up to the present time, almost 60 lexicographic works— dictionaries, vocabularies, glossaries — have been published, in a range of metalanguages, fromEnglish to Hausa itself. This article traces the historical development of the major studies accordingto their type and function as general reference works, specialized works, pedagogical works, andterminological works. For each work, there is a general discussion of its size, accuracy of the phonological,lexical, and grammatical information, and the adequacy of its definitions and illustrativematerial. A complete list of the lexicographic works is included.

Keywords: ARABIC, BILINGUAL LEXICOGRAPHY, DIALECTAL VARIANTS, DICTIONARIES,ENGLISH, ETYMOLOGIES, FRENCH, GERMAN, GLOSSARIES, GRAMMATICALCATEGORIES, HAUSA, LANGUAGE LEARNING, LOANWORDS, NEOLOGISMS, NIGER,NIGERIA, ORTHOGRAPHY, PHONETIC TRANSCRIPTION, PHONOLOGY, RUSSIAN, STANDARDDIALECT, STANDARDIZATION, TERMINOLOGY, VOCABULARIES, WEST AFRICA.

Opsomming: Die leksikografiese tradisie in Hausa. Hausa, 'n belangrike taal vanWes-Afrika, is een van die tale van Afrika suid van die Sahara wat die wydste bestudeer word. Dithet 'n ryk leksikografiese tradisie wat ongeveer twee eeue oud is. Van die eerste groot woordeboekwat in 1843 gepubliseer is tot die hede is ongeveer 60 leksikografiese werke — woordeboeke,naamlyste, woordelyste — gepubliseer in 'n reeks metatale van Engels tot Hausa self. Hierdie artikelgaan die historiese ontwikkeling van die groter studies aan die hand van hulle tipe en funksieas algemene naslaanwerke, gespesialiseerde werke, opvoedkundige werke, en terminologiesewerke na. Vir elke werk is daar 'n algemene bespreking oor sy grootte, akkuraatheid van die fonologiese,leksikale en

Internationalization of Bachelor’s programmes in Social Work in Europe

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Peter Hendriks

2016-03-01

Full Text Available Internationalization of Bachelor’s programmes in Social Work in EuropeThis article presents the results of a survey on the internationalization of Bachelor’s education in social work, which was carried out at 33 schools of social work across Europe. Many universities are seeking to “internationalize” their social work curriculum. However, although many social work educators are convinced of the importance of cross-border exchange, others are sceptical about the added value of internationalization for a professional career in social work. The aim of this study is to contribute to the discussion about the significance of internationalizing the curriculum of Bachelor’s programmes in social work. Since internationalization in itself is an ideological endeavour, educators must reflect on and formulate their own ideological motives and aspirations. To this end, representatives of schools of social work completed a questionnaire concerning the aim of internationalization, the structure of the curriculum, student and staff mobility, international policies and challenges. This study demonstrates that all universities have added an international dimension to their curricula. Many educators believe that internationalizing the social work curriculum contributes to qualitatively better future professionals “at home”. However, most of the respondents are dissatisfied with what has actually been achieved in terms of their universities’ international ambitions. This is due to a lack of language skills and facilities. Above all, we think, that this dissatisfaction is related to the underlying debate on universalism and indigenization in social work practice and education.  SAMENVATTINGDe internationalisering van de bachelors sociaal werk in EuropaIn dit artikel worden de uitkomsten gepresenteerd van een survey naar internationalisering van het sociaal werk bachelor onderwijs, uitgevoerd onder 33 opleidingen sociaal werk, verspreid over Europa

An attempt at determining Des of glacial sediments using different luminescence methods

International Nuclear Information System (INIS)

Ou Xianjiao; Lai Zhongping; Zeng Lanhua

2013-01-01

Background: Absolute dating is the key technical issue of Quaternary glacial research. Optically stimulated luminescence (OSL) has been increasingly applied to Quaternary glacial dating in recent years. However, problems such as insufficient bleaching, low luminescence sensitivity, high thermal transfer effect, etc, still remain. Purpose: In order to investigate the applicability of equivalent dose (D e ) determination of glacial sediments by different OSL methods, six samples were collected from the Yingpu Valley of eastern Qinghai-Tibetan Plateau (two samples from modern glacial sediments, three from moraines and glacial terrace attributed to Neoglacial and one from a moraine attributed to the last glaciation). Methods: The D e s were determined by SAR combined SGC technique, using three methods: quartz large aliquot (6 mm) BSL, small aliquot (2/3 mm) BSL and polymineral IRSL. Results: D e s determined by SGC are consistent with D e s determined by SAR protocol. Comparison of three methods shows that IRSL D e >large aliquot BSL D e >small aliquot BSL D e . D e s of polymineral IRSL are obviously higher than quartz BSL. Conclusions: It is obviously that feldspar is more difficult to reset than quartz, thus is not suitable for dating glacial sediments in this region. Quartz large aliquot method is suitable for well bleached glacial samples. Due to the low luminescence sensitivity of quartz, small aliquot method showed poor luminescence characteristics. Moreover, this method cannot distinguish the poor bleached grains in this measurement. However, it is possible that quartz small aliquot, even single grain method could be used to date older or brighter glacial samples. More works are required to solve the problems we have encountered in dating low sensitivity glacial sediments. (authors)

A qualitative exploration of trial-related terminology in a study involving Deaf British Sign Language users.

Science.gov (United States)

Young, Alys; Oram, Rosemary; Dodds, Claire; Nassimi-Green, Catherine; Belk, Rachel; Rogers, Katherine; Davies, Linda; Lovell, Karina

2016-04-27

Internationally, few clinical trials have involved Deaf people who use a signed language and none have involved BSL (British Sign Language) users. Appropriate terminology in BSL for key concepts in clinical trials that are relevant to recruitment and participant information materials, to support informed consent, do not exist. Barriers to conceptual understanding of trial participation and sources of misunderstanding relevant to the Deaf community are undocumented. A qualitative, community participatory exploration of trial terminology including conceptual understanding of 'randomisation', 'trial', 'informed choice' and 'consent' was facilitated in BSL involving 19 participants in five focus groups. Data were video-recorded and analysed in source language (BSL) using a phenomenological approach. Six necessary conditions for developing trial information to support comprehension were identified. These included: developing appropriate expressions and terminology from a community basis, rather than testing out previously derived translations from a different language; paying attention to language-specific features which support best means of expression (in the case of BSL expectations of specificity, verb directionality, handshape); bilingual influences on comprehension; deliberate orientation of information to avoid misunderstanding not just to promote accessibility; sensitivity to barriers to discussion about intelligibility of information that are cultural and social in origin, rather than linguistic; the importance of using contemporary language-in-use, rather than jargon-free or plain language, to support meaningful understanding. The study reinforces the ethical imperative to ensure trial participants who are Deaf are provided with optimum resources to understand the implications of participation and to make an informed choice. Results are relevant to the development of trial information in other signed languages as well as in spoken/written languages when

Effects of birthplace and individual genetic admixture on lung volume and exercise phenotypes of Peruvian Quechua.

Science.gov (United States)

Brutsaert, Tom D; Parra, Esteban; Shriver, Mark; Gamboa, Alfredo; Palacios, Jose-Antonio; Rivera, Maria; Rodriguez, Ivette; León-Velarde, Fabiola

2004-04-01

Forced vital capacity (FVC) and maximal exercise response were measured in two populations of Peruvian males (age, 18-35 years) at 4,338 m who differed by the environment in which they were born and raised, i.e., high altitude (Cerro de Pasco, Peru, BHA, n = 39) and sea level (Lima, Peru, BSL, n = 32). BSL subjects were transported from sea level to 4,338 m, and were evaluated within 24 hr of exposure to hypobaric hypoxia. Individual admixture level (ADMIX, % Spanish ancestry) was estimated for each subject, using 22 ancestry-informative genetic markers and also by skin reflectance measurement (MEL). Birthplace accounted for the approximately 10% larger FVC (P < 0.001), approximately 15% higher maximal oxygen consumption (VO(2)max, ml.min(-1).kg(-1)) (P < 0.001), and approximately 5% higher arterial oxygen saturation during exercise (SpO(2)) (P < 0.001) of BHA subjects. ADMIX was low in both study groups, averaging 9.5 +/- 2.6% and 2.1 +/- 0.3% in BSL and BHA subjects, respectively. Mean underarm MEL was significantly higher in the BSL group (P < 0.001), despite higher ADMIX. ADMIX was not associated with any study phenotype, but study power was not sufficient to evaluate hypotheses of genetic adaptation via the ADMIX variable. MEL and FVC were positively correlated in the BHA (P = 0.035) but not BSL (P = 0.335) subjects. However, MEL and ADMIX were not correlated across the entire study sample (P = 0.282). In summary, results from this study emphasize the importance of developmental adaptation to high altitude. While the MEL-FVC correlation may reflect genetic adaptation to high altitude, study results suggest that alternate (environmental) explanations be considered. Copyright 2003 Wiley-Liss, Inc.

The Contribution of F.W. Taylor to Industrial and Organizational Psychology

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E. C. Thomas

1982-11-01

In die artikel word getoon dat F.W. Taylor die erkende "vader van wetenskaplike bestuur" ook erkenning behoort te geniet as grondlegger van die Bedryf en -organisasiesielkunde. Sy werk op die terreine van prestasiemotivering en tevredenheid, opleiding, plasing van werkers, bestuurs- en organisasieontwikkeling en arbeidsverhoudinge het waarskynlik die werk van erkende sielkundiges op hierdie gebiede vooruitgeloop, of grondslag daarvoor gelê. Daar word tot die slotsom gekom dat alhoewel Taylor nie 'n opgeleide sielkundige was nie, hy en sy kollegas erkenning moet kry vir die praktiese implimentering van die beginsels en teorieë van die moderne Bedryf- en Organisasiesielkunde.

SWITCHED REFERENCE PHASE LOCK LOOP (SRPLL)

International Nuclear Information System (INIS)

KERNER, T.

2001-01-01

The Brookhaven National Laboratory Relativistic Heavy Ion Collider (RHIC) has two beam synchronous event links (BSL), one for each ring, which use the 28 MHz ring low level rf to distribute event codes synchronously with a precise phase relationship to the beam. During a cogging reset just before injection, the low level rf sine wave is interrupted which causes the BSL receivers to lose lock. Lock loss in turn causes false triggers and other undesirable-effects on the beam position monitors (BPM), ionization profile monitors (IPM), the tune meter and various experiments which use the BSLs. To rectify these problems, a SRPLL has been inserted between the beam synchronous master and the low level rf source. The SRPLL inserts a frequency and phase continuous splice over the dead-band gap in the rf source created during a cogging reset. The splice removes the gap and prevents the distributed BSL receivers from losing lock

Stimmen des Leis, schillernde Gewebe / Christoph Schlüren

Index Scriptorium Estoniae

Schlüren, Christoph

1995-01-01

Baltische Werke für Streichorchester: Vol. 1: Balakauskas: Ostrobothnian Symphony, Vasks: Symphonie "Stimmen", Narbutaite: Opus Lugubre; Vol. 2: Kutavicius: Nothern Gates, Vasks: Cantabile, Tüür: Insula Deserta, Rekasius: Music for strings, Werke von Urbaitis und Juozapaitis; Ostrobothnian Chamber Orchestra, Dirigent: Juha Kangas; Finlandia / east-west CD-s 4509-97892-2 und 4509-97893-2. Vasks: Cantabile, Englischhorn-Konzert, Botschaft, Musica dolorosa, Lauda; Riga Philarmonic Orchestra, Dirigent: Kriss Rusmanis; Confer / BMG 75605-51236-2. Eller: Morgenrot, Abendrot, 5 Stücke für Streicher, Geister, Im Schatten und im Sonnenlicht, Elegia; Estonian Symphony Orchestra, Dirigent: Peeter Lilje; Forte FD 0020/2. Tubin: 11. Symphonie, Elegie für Streicher, Raid: 2. Symphonie; Estnisches Staatliches Symphonieorchester, Dirigent: Arvo Volmer; Koch 3-7291-2 H1. Sumera: Symphonien 1-3; Malmö Symphony Orchestra, Dirigent: Paavo Järvi; BIS/Disco-Center 660. Sumera: Klavierkonzert, 4. Symphonie, Musica tenera; Malmö Symphony Orchestra, Dirigent: Paavo Järvi; BIS/Disco-Center 690. Tormis: Werke für Männerchor; Estnischer Nationaler Männerchor, Dirigent: Olev Oja; Forte CDs FD 0011/2 und FD 0019/2 Tutvustatakse uusi heliplaate Baltimaade heliloojate loomingust.

‘Op de wijze van Kavafis’: Die voorbeeld van die digter uit Alexandrië

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Phil van Schalkwyk

2014-12-01

Full Text Available Die Griekse digter K.P. Kavafis (1863–1933 word wêreldwyd deur lesers sowel as skrywers besonder hoog geag. Hy het nie net van die grootste twintigste-eeuse skrywers beïnvloed nie,maar is vanweë die buitengewone vertaalbaarheid van sy werk ook betreklik sterk teenwoordig in die letterkunde van meer tale as slegs Grieks en Engels. Vir baie – veral gay lesers, skrywers en kunstenaars – besit Kavafis ’n voorbeeldstatus, ten opsigte van die letterkunde sowel asdie lewe. W.H. Auden het beweer dat dit wat Kavafis onderskei, sy stemtoon is, een wat ’n persoon met ’n unieke perspektief op die wêreld openbaar. Hierdie bydrae, wat deel is van ’nnavorsingsprojek oor idiolektiese skrywersidentiteit, is daarop gerig om die onderskeidende kenmerke van Kavafis se werk, sowel in terme van vorm as inhoud, opnuut te ondersoek. Dit word gedoen binne die raamwerk van die breë kritiese diskoers oor Kavafis en met verwysing na enkele manifestasies/voorbeelde van Nederlandse en Afrikaanse kritiese en kreatieweperspektiewe op sy poësie, met die doel om spesifiek lig te werp op die besondere soortwysheid wat in Kavafis se werk oorgedra word.

Ingeborg Drewitz im literarischen und politischen Feld Ingeborg Drewitz in the Field of Literature and Politics

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Regina Schleicher

2007-03-01

Full Text Available Der aus einer Berliner Tagung im November 2003 hervorgegangene Band „Von der Unzerstörbarkeit des Menschen“ versammelt zahlreiche interessante Beiträge zu Leben und Werk der Autorin Ingeborg Drewitz. Der erste Teil des Bandes ist unter dem Titel „Vita activa“ vor allem dem vielfältigen politischen Engagement der Autorin gewidmet, während „Themen und Schreibweisen“ ihres literarischen Werks in einem sehr umfangreichen zweiten Teil behandelt werden. Insgesamt zeichnen die Texte in dem Band ein sehr differenziertes Bild von Ingeborg Drewitz als engagierter Schriftstellerin und von ihrem Werk.The volume “On Human Indestructibility” (“Von der Unzerstörbarkeit des Menschen“, which is based on a conference held in Berlin in November 2003, contains numerous interesting contributions on the life and work of the author Ingeborg Drewitz. The first part of the volume, which is entitled “Vita activa,” is dedicated to the author’s numerous political engagements, while the expansive second section, “Themes and Syntax,” approaches her literary work. In total, the texts in the volume draw a differentiated image of the politically engaged author Ingeborg Drewitz and of her work.

Triage and management of accidental laboratory exposures to biosafety level-3 and -4 agents.

Science.gov (United States)

Jahrling, Peter; Rodak, Colleen; Bray, Mike; Davey, Richard T

2009-06-01

The recent expansion of biocontainment laboratory capacity in the United States has drawn attention to the possibility of occupational exposures to BSL-3 and -4 agents and has prompted a reassessment of medical management procedures and facilities to deal with these contingencies. A workshop hosted by the National Interagency Biodefense Campus was held in October 2007 and was attended by representatives of all existing and planned BSL-4 research facilities in the U.S. and Canada. This report summarizes important points of discussion and recommendations for future coordinated action, including guidelines for the engineering and operational controls appropriate for a hospital care and isolation unit. Recommendations pertained to initial management of exposures (ie, immediate treatment of penetrating injuries, reporting of exposures, initial evaluation, and triage). Isolation and medical care in a referral hospital (including minimum standards for isolation units), staff recruitment and training, and community outreach also were addressed. Workshop participants agreed that any unit designated for the isolation and treatment of laboratory employees accidentally infected with a BSL-3 or -4 pathogen should be designed to maximize the efficacy of patient care while minimizing the risk of transmission of infection. Further, participants concurred that there is no medically based rationale for building care and isolation units to standards approximating a BSL-4 laboratory. Instead, laboratory workers accidentally exposed to pathogens should be cared for in hospital isolation suites staffed by highly trained professionals following strict infection control procedures.

Deglacial sea level history of the East Siberian Sea and Chukchi Sea margins

Science.gov (United States)

Cronin, Thomas M.; O'Regan, Matt; Pearce, Christof; Gemery, Laura; Toomey, Michael; Semiletov, Igor; Jakobsson, Martin

2017-09-01

Deglacial (12.8-10.7 ka) sea level history on the East Siberian continental shelf and upper continental slope was reconstructed using new geophysical records and sediment cores taken during Leg 2 of the 2014 SWERUS-C3 expedition. The focus of this study is two cores from Herald Canyon, piston core SWERUS-L2-4-PC1 (4-PC1) and multicore SWERUS-L2-4-MC1 (4-MC1), and a gravity core from an East Siberian Sea transect, SWERUS-L2-20-GC1 (20-GC1). Cores 4-PC1 and 20-GC were taken at 120 and 115 m of modern water depth, respectively, only a few meters above the global last glacial maximum (LGM; ˜ 24 kiloannum or ka) minimum sea level of ˜ 125-130 meters below sea level (m b.s.l.). Using calibrated radiocarbon ages mainly on molluscs for chronology and the ecology of benthic foraminifera and ostracode species to estimate paleodepths, the data reveal a dominance of river-proximal species during the early part of the Younger Dryas event (YD, Greenland Stadial GS-1) followed by a rise in river-intermediate species in the late Younger Dryas or the early Holocene (Preboreal) period. A rapid relative sea level rise beginning at roughly 11.4 to 10.8 ka ( ˜ 400 cm of core depth) is indicated by a sharp faunal change and unconformity or condensed zone of sedimentation. Regional sea level at this time was about 108 m b.s.l. at the 4-PC1 site and 102 m b.s.l. at 20-GC1. Regional sea level near the end of the YD was up to 42-47 m lower than predicted by geophysical models corrected for glacio-isostatic adjustment. This discrepancy could be explained by delayed isostatic adjustment caused by a greater volume and/or geographical extent of glacial-age land ice and/or ice shelves in the western Arctic Ocean and adjacent Siberian land areas.

Konstruktivisme, konstruksionisme en maatskaplike werk

Directory of Open Access Journals (Sweden)

M.J.M. du Plessis

2000-03-01

Full Text Available Constructivism, constructionism and social workIn this article the constructivistic framework of reasoning is illustrated with reference to the premises of the structure determinism of Maturana, Kelly's personality constructs theory, and the radical constructivism as developed by Von Glasersfeld. Proceeding to the constructivistic frame of thought that reality is created by each individual with reference to particular internal processes (specifically cognitive processes, constructionism indicates, according to the social construct theory, that the interaction between individuals is responsible for the process of reality creation. The core of the frameworks of reasoning involves that reality is not created by the individual or individuals, and that, therefore not only one objective reality exists, but in fact a range of subjective realities - realities that are continually adapted by means of a process of evolution. As the individual is exposed to new experiences, he attaches new unique meanings to it, and this continually creates another reality. This view implies specific implications for the profession of Social Work. For example, final and objective diagnoses about persons, families, groups or communities cannot be made, as such diagnoses are based on a subjective reality created by a social worker in a certain situation. Indeed, there is no objective reality against which those concerned could be measured in order to come to a conclusion. Further, constructivism and constructionism imply that the social worker departs from a position of "not-knowing". He is therefore not the only skilled person, but seeks, together with the client, new realities that could contain the solution of the problems of the client.

Global Ear. Werke 2001 - 2006

Index Scriptorium Estoniae

2006-01-01

Dresdenis muusikafestivalil "Global Ear" 23.3.03 esitusel Eesti heliloojate muusika: Helena Tulve "lumineux/opaque", Jaan Rääts "Meditation", Mirjam Tally "Aura", Mati Kuulberg "Sonate Nr.4", Mari Vihmand "Seitsmele"

Rapid screening for entry inhibitors of highly pathogenic viruses under low-level biocontainment.

Directory of Open Access Journals (Sweden)

Aparna Talekar

Full Text Available Emerging viruses including Nipah, Hendra, Lujo, and Junin viruses have enormous potential to spread rapidly. Nipah virus, after emerging as a zoonosis, has also evolved the capacity for human-to-human transmission. Most of the diseases caused by these pathogens are untreatable and require high biocontainment conditions. Universal methods for rapidly identifying and screening candidate antivirals are urgently needed. We have developed a modular antiviral platform strategy that relies on simple bioinformatic and genetic information about each pathogen. Central to this platform is the use of envelope glycoprotein cDNAs to establish multi-cycle replication systems under BSL2 conditions for viral pathogens that normally require BSL3 and BSL4 facilities. We generated monoclonal antibodies against Nipah G by cDNA immunization in rats, and we showed that these antibodies neutralize both Nipah and Hendra live viruses. We then used these effective Henipavirus inhibitors to validate our screening strategy. Our proposed strategy should contribute to the response capability for emerging infectious diseases, providing a way to initiate antiviral development immediately upon identifying novel viruses.

Early vocabulary development in deaf native signers: a British Sign Language adaptation of the communicative development inventories.

Science.gov (United States)

Woolfe, Tyron; Herman, Rosalind; Roy, Penny; Woll, Bencie

2010-03-01

There is a dearth of assessments of sign language development in young deaf children. This study gathered age-related scores from a sample of deaf native signing children using an adapted version of the MacArthur-Bates CDI (Fenson et al., 1994). Parental reports on children's receptive and expressive signing were collected longitudinally on 29 deaf native British Sign Language (BSL) users, aged 8-36 months, yielding 146 datasets. A smooth upward growth curve was obtained for early vocabulary development and percentile scores were derived. In the main, receptive scores were in advance of expressive scores. No gender bias was observed. Correlational analysis identified factors associated with vocabulary development, including parental education and mothers' training in BSL. Individual children's profiles showed a range of development and some evidence of a growth spurt. Clinical and research issues relating to the measure are discussed. The study has developed a valid, reliable measure of vocabulary development in BSL. Further research is needed to investigate the relationship between vocabulary acquisition in native and non-native signers.

Anfangen, sich die Welt anders vorzustellen Beginning to Imagine the World Differently

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Sabine Fuchs

2006-11-01

Full Text Available Der Sammelband Butler Matters bezeugt Judith Butlers außerordentliche Bedeutung für feministische und queere Studien und Forschung. In elf Beiträgen wird Butlers (frühes Werk von Gender Trouble und Bodies That Matter über Excitable Speech bis zu The Psychic Life of Power betrachtet und sein weit reichender Einfluss quer durch die wissenschaftlichen Disziplinen nachgewiesen. Dargestellt werden auch die kontroverse Rezeption von Butlers Werk sowie die politischen Wirkungen von Butlers Denken. Besonders anregend ist ein zweiteiliges Interview mit Judith Butler, in dem sie auf ein breites Spektrum von Fragen eingeht, die auch wichtige Themen ihrer aktuelleren Werke betreffen.The collected volume Butler Matters testifies to Judith Butler’s extraordinary importance for feminist and queer studies and for gender research. The eleven contributions examine Butler’s (early work—including Gender Trouble, Bodies that Matter, Excitable Speech, and The Psychic Life of Power—and prove its expansive influence across scholarly disciplines. The volume also portrays the controversial reception of Butler’s work as well as the political ramifications of her thinking. A two-part interview with Judith Butler, in which she approaches questions on a broad spectrum including important themes concerning her recent work, is particularly inspiring.

Plaadid / Katrin Malt, Virko Pirrus, Mart Kalvet

Index Scriptorium Estoniae

Malt, Katrin

2008-01-01

Uutest heliplaatidest Atrocity "Werk 80 II", Benighted "Icon", Brain Drill "Apocalyptic Feasting", BrainStorm "Downburst", Diablo Swing Orchestra "The Butcher's Ballroom", Floodstain "Dreams Make Monters", Foxy Shazam "Introducting Foxy Shazam"

Rezension zu: Uta Felten, Tanja Schwan (Hg.: Frida Kahlo. Berlin: edition tranvía – Verlag Walter Frey 2008

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Tabea Huth

2009-07-01

Full Text Available Im vorliegenden Sammelband bemühen sich die Autor/-innen um eine Neubewertung des Werks der mexikanischen Künstlerin Frida Kahlo (1907–1954 im Kontext aktueller theoretischer Debatten und stellen die Frage nach der Verortung der Künstlerin in der zeitgenössischen mexikanischen und europäischen Kunstszene. Unter der Verwendung von theoretischen Ansätzen aus der Erforschung von Intermedialität, Gender, Performanz und Hybridität sowie Inspirationen aus der postkolonialen Theorie analysieren die Autoren/-innen das Zusammenspiel von Leben, Werk und Rezeption der Künstlerin. Das Interesse an der Inszenierung des fragmentierten weiblichen Körpers im Kontext kultureller Hybridität verbindet die einzelnen Aufsätze – was leider im Titel des Bandes nicht ganz deutlich wird.

Leipoldt in 1980*

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H. M. Viljoen

1980-03-01

Full Text Available Oor Leipoldt se veelsydigheid hoef daar nie veel gésê te word nie. Hy was digter, dramaturg, romanskrywer, joemalis, geneesheer, kos- en wynkenner, filantroop, wêreldburger, maar bly tog vir ons in die eerste plek digter. Ons beeld van Leipoldt so oeuvre kan verander - daar is vanjaar al twee “nuwe” werke van hom ontdek - maar as daar iets van Leipoldt behoue sal bly, sal dit eerder sy poësie as sy drama, prosa, joemalistieke werk of kookboeke wees; so lyk dit altans op die oomblik. Daarom beperk ek my to t sy poësie en sal ek nie probeer om u totaalbeeld van sy ryk maar erg ongelyke oeuvre te gee nie.

78 FR 49753 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

Science.gov (United States)

2013-08-15

... KSTW Holdings, Inc.; Steinway Musical Instruments, Inc.; KSTW Holdings, Inc. 20131063 G Quad-C Partners...; Marketing Werks, Inc.; WP Horizon Topco LLC. 07/23/2013 20131051 G Novo Nordisk Foundation; Ophthotech...

Hans-Heinrich Nolte (Hg.), Klaas Bähre (Red.), Innere Peripherien in Ost und West / [rezensiert von] Helmut Klüter

OpenAIRE

Klüter, Helmut

2008-01-01

Rezensiertes Werk: Innere Peripherien in Ost und West / Hrsg.: Hans-Heinrich Nolte. Red.: Klaas Bähre. - Stuttgart : Steiner, 2001. - 187 S. : Kt. - (Historische Mitteilungen : Beiheft ; 42) ISBN 3-515-07972-6

A tactile P300 brain-computer interface

NARCIS (Netherlands)

Brouwer, A.M.; Erp, J.B.F. van

2010-01-01

De werking van de eerste Brain-Computer-Interface gebaseerd op tactiele EEG response wordt gedemonstreerd en het effect van het aantal gebruikte vibro-tactiele tactoren en stimulus-timing parameters wordt onderzocht

Health status of elderly based on daily activities living, cholesterol and uric acid profile in Medan city

Science.gov (United States)

Amelia, R.; Harahap, J.; Wahyuni, A. S.; Pratama, A.

2018-03-01

Health problems in the elderly come from declining body cells, so the function and body endurance decreased along with increased risk factors for diseases. This study aimed to determine the elderly health status in Public Health Center of Tuntungan Medan. Health status includes measurement of daily activities living (DAL),and health parameter include blood pressure, blood sugar level (BSL), cholesterol level and uric acid level. The study design was descriptive with cross-sectional approach. The study population was the entire elderly population residing in the service area of public health center of Tuntungan Medan (55 subjects). The elderly who had a reasonable level of independence were 47 subjects (85.5%), the majority of elderly were in the category of hypertension stage I (20 subjects; 36.4%) with a mean systolic blood pressure level was 143mmHg. Most of them have BSL that exceeded the standard limit (42 subjects; 76.4%) with BSL mean value was 177mg/dL.Uric acid levels were in the high category (34 subjects; 61.98%) with a mean value of 7.0mm/dL, and most of them have normal cholesterol (43 subjects; 78.2%).

Inactivation of RNA Viruses by Gamma Irradiation: A Study on Mitigating Factors

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Adam J. Hume

2016-07-01

Full Text Available Effective inactivation of biosafety level 4 (BSL-4 pathogens is vital in order to study these agents safely. Gamma irradiation is a commonly used method for the inactivation of BSL-4 viruses, which among other advantages, facilitates the study of inactivated yet morphologically intact virions. The reported values for susceptibility of viruses to inactivation by gamma irradiation are sometimes inconsistent, likely due to differences in experimental protocols. We analyzed the effects of common sample attributes on the inactivation of a recombinant vesicular stomatitis virus expressing the Zaire ebolavirus glycoprotein and green fluorescent protein. Using this surrogate virus, we found that sample volume and protein content of the sample modulated viral inactivation by gamma irradiation but that air volume within the sample container and the addition of external disinfectant surrounding the sample did not. These data identify several factors which alter viral susceptibility to inactivation and highlight the usefulness of lower biosafety level surrogate viruses for such studies. Our results underscore the need to validate inactivation protocols of BSL-4 pathogens using “worst-case scenario” procedures to ensure complete sample inactivation.

Experimental Investigation of Turbine Endwall Heat Transfer. Volume I. Description of Experimental Hardware and Test Conditions.

Science.gov (United States)

1981-08-01

scanner Scanivalve system with 288 ports Pressure transducers Druck , with ranges from 0-10 psia to 0-500 psia Accuracy + 0.06% BSL Thermocouple channels...Pressure scanner Scanivalve system with 120 trapping ports Pressure transducers Druck , with 0-25 psia to 0-100 psia Accuracy + 0.05% BSL Thermocouple...ob 7, o5?.q 1 3 3d I7 -I0Y 2.5.52 0 71 7, 9. 3 t2 b O0 b 2. ~ , 692.4 ",.333 1-69 -.579 71. 7.* Q4¥ 8, ** -. 19 06Jo-4 -Sie4 % -433.14.2 2.266A 01

Recht autonom

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Robert von Friedeburg

2010-01-01

Full Text Available Rezensiertes Werk: Christopher W. Brooks, Law, Politics and Society in Early Modern England, Cambridge [u. a.]: Cambridge University Press 2008, XII, 456 S., ISBN 978-0-521-32391-8

Unglückbringende Sprachen

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Gabriele von Olberg-Haverkate

2010-01-01

Full Text Available Rezensiertes Werk: Peter Friedrich, Manfred Schneider (Hg., Fatale Sprachen. Eid und Fluch in Literaturund Rechtsgeschichte, Paderborn, München: Wilhelm Fink 2009, 348 S., ISBN 978-3-7705-4740-1

Dichtung als Blüte der Wahrheit Fiction as Blossom of Truth

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Susanne Gramatzki

2006-03-01

Full Text Available Kaum eine andere Schriftstellerin hat so konsequent – man ist versucht, zu sagen: so ernsthaft – mit fremden Identitäten gespielt wie Else Lasker-Schüler, die sich selbst als Tino von Bagdad oder Prinz Jussuf von Theben imaginierte und ihren Freunden erfindungsreiche Namen beilegte. Realität und Phantasie flossen in ihrem Leben und Werk stets zusammen. Sigrid Bauschinger, ehemalige Professorin an der University of Massachusetts und bereits 1980 mit einer umfangreichen Studie über Else Lasker-Schüler hervorgetreten (Else Lasker-Schüler. Ihr Werk und ihre Zeit, hat es nun unternommen, auf Grundlage bisher unveröffentlicher Dokumente eine neue Biographie der bedeutenden Wuppertaler Autorin zu verfassen.Almost no other female author has played with foreign identities as consistently—one could almost say as seriously—as Else Lasker-Schüler, who fashioned herself as Tino von Baghdad or Prince Jussuf von Theben and affixed her friends with imaginative names. Reality and fantasy were intertwined in her life and work. Sigrid Bauschinger, formerly professor at the University of Massachusetts, already presented a comprehensive study of Else Lasker-Schüler in 1980 (Else Lasker-Schüler. Ihr Werk und ihre Zeit/Else Lasker-Schüler. Her Work and Her Time. She has now written a new biography of the Wuppertal author based on previously unpublished documents.

Beats on the Table: Beat Writing in the Chicago Review and Big Table

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Jaap van der Bent

2012-07-01

Full Text Available Normal 0 21 false false false NL X-NONE X-NONE MicrosoftInternetExplorer4 Kleine literaire tijdschriften, zogenaamde little magazines, hebben een belangrijke rol gespeeld bij de doorbraak, in de loop van de jaren vijftig, van de Amerikaanse Beat Generation. Aangezien grotere uitgeverijen en de gevestigde tijdschriften lange tijd terugschrokken voor de zowel inhoudelijk als formeel van de norm afwijkende uitingen van de Beats, verscheen hun werk aanvankelijk vooral in kleinere tijdschriften als de twee waaraan in dit artikel aandacht wordt besteed: de Chicago Review en Big Table. Aan de hand van een beschrijving van de inhoud van deze twee tijdschriften wordt geprobeerd duidelijk te maken hoe het werk van de Beat Generation zich in deze tijdschriften gaandeweg een eigen plaats verwierf. Speciale aandacht wordt besteed aan de rol van de redacteuren Irving Rosenthal en Paul Carroll; door zijn uitgekiende strategie om voor het omstreden werk van Beat-auteur William S. Burroughs geleidelijk een steeds grotere plaats in te ruimen, bepaalde vooral Rosenthal het veranderende karakter van de Chicago Review. De veranderingen bij dat tijdschrift verliepen niet zonder slag of stoot en waren voor de eigenaar ervan, de University of Chicago, op een gegeven moment aanleiding om de Chicago Review aan censuur te onderwerpen. Ook deze censuur en de reactie erop, de oprichting van Big Table, worden in het artikel belicht.

Everything-as-it-should-be-Blackstone?

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Kent D. Lerch

2010-01-01

Full Text Available Rezensiertes Werk: Wilfrid R. Prest, William Blackstone. Law and Letters in the Eighteenth Century, Oxford [u. a.]: Oxford University Press 2008, XVII, 355 S., ISBN 978-0-19-955029-6

Nicht nur böse Christen

Directory of Open Access Journals (Sweden)

Andreas Thier

2003-01-01

Full Text Available Rezensiertes Werk: John Witte jr., Law and Protestantism. The Legal Teachings of the Lutheran Reformation, New York, Cambridge: Cambridge University Press 2002, XX, 337 S., ISBN 0-521-78132-9

Budke, Alexandra; Kanwischer, Detlef; Pott, Andreas (Hg.), Internetgeographien : Beobachtungen zum Verhältnis von Internet, Raum und Gesellschaft / [rezensiert von] Helmut Klüter

OpenAIRE

Klüter, Helmut

2009-01-01

Rezensiertes Werk: Internetgeographien : Beobachtungen zum Verhältnis von Internet, Raum und Gesellschaft / hrsg. von Alexandra Budke ... - Stuttgart : Steiner, 2004. - 192 S. : Ill., graph. Darst., Kt. - (Erdkundliches Wissen ; 136) ISBN 3-515-08506-8

Allwissende Kollegen

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Valentin Groebner

2008-01-01

Full Text Available Rezensiertes Werk:Jaana Eichhorn, Geschichtswissenschaft zwischen Tradition und Innovation. Diskurse, Institutionen und Machtstrukturen der bundesdeutschen Frühneuzeitforschung, Göttingen: Vandenhoeck Ruprecht 2006, 476S., ISBN 978-3-89971-294-0

Verlies van (thuis en haard. Het belang van verliesbegeleiding als onderdeel van de maatschappelijke begeleiding binnen het Vluchtelingenwerk, regio Utrecht

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Birgit Hoogenberk

2014-06-01

Full Text Available Loss of home and house. The importance of loss counseling as a part of refugee social supportIn this article it is advocated that it is important that the implementation of loss counseling is part of social support for refugees, also called integrative eclectic working. Social support from VluchtelingenWerk, also known as Refugee Council, is about supporting the client in an effective manner with their personal problems which can hinder their integration. Because the target group of VluchtelingenWerk is a group of people whom have suffered many losses, attention should be brought to this subject. Unfortunately in current work methods there is no room for loss counseling, partly due to the lack of methodological tools. The losses associated with this group have a lot of impact on their daily lives and often are the source of functional limitations. By offering loss counseling and multi-method grief counseling, volunteers and employees are offered tools to make loss more negotiable. In this article different examples will be discussed and the new loss model of Stroebe and Schut will be explained. What will be clarified is the importance of the implementation of loss counseling, for the well-being and the integration process of clients as well as achieving organizational goals.Verlies van (thuis en haard. Het belang van verliesbegeleiding als onderdeel van de maatschappelijke begeleiding binnen het VluchtelingenWerk, regio UtrechtIn dit artikel wordt gepleit voor het implementeren van verliesbegeleiding als onderdeel van de maatschappelijke begeleiding, er is sprake van integratief eclectisch werken. De maatschappelijke begeleiding van het VluchtelingenWerk heeft als taak de cliënt zo goed mogelijk te begeleiden bij persoonlijke problemen die de inburgering kunnen belemmeren. Aangezien de doelgroep van het VluchtelingenWerk bestaat uit mensen die ontzettend veel verliezen hebben geleden dient hier aandacht voor te zijn. Helaas is in de huidige

49th report of the Arbeitsgemeinschaft Rhein-Wasserwerke e.V.. Annual report 1992

International Nuclear Information System (INIS)

1992-01-01

The annual report of the Arbeitsgemeinschaft Rhein-Wasserwerke (ARW) discusses the following subjects: (1) ARW report on water quality; (2) the problem of herbicides and pesticides; (3) Duesseldorf-Flehe Rhine river monitoring station - construction and performance; (4) observations concerning the aerobic degradation capacity of the river banks as a functional of the seasonal temperature variations of the Rhine; (5) results of Rhine water analyses of GEW-Werke Koeln AG in 1992; (6) statistical methods of generating groundwater levels in ground water aquifers under the influence of outfall ditches. The appendix contains the analyses of the year 1992, the data acquired by GEW-Werke Koeln AG for 1992, the 1993 monitoring programme, and a survey of the organisational structure of the Arbeitsgemeinschaft Rhein-Wasserwerke e.V. (orig./BRR) [de

Effects of sleep deprivation on central auditory processing

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Liberalesso Paulo Breno

2012-07-01

Full Text Available Abstract Background Sleep deprivation is extremely common in contemporary society, and is considered to be a frequent cause of behavioral disorders, mood, alertness, and cognitive performance. Although the impacts of sleep deprivation have been studied extensively in various experimental paradigms, very few studies have addressed the impact of sleep deprivation on central auditory processing (CAP. Therefore, we examined the impact of sleep deprivation on CAP, for which there is sparse information. In the present study, thirty healthy adult volunteers (17 females and 13 males, aged 30.75 ± 7.14 years were subjected to a pure tone audiometry test, a speech recognition threshold test, a speech recognition task, the Staggered Spondaic Word Test (SSWT, and the Random Gap Detection Test (RGDT. Baseline (BSL performance was compared to performance after 24 hours of being sleep deprived (24hSD using the Student’s t test. Results Mean RGDT score was elevated in the 24hSD condition (8.0 ± 2.9 ms relative to the BSL condition for the whole cohort (6.4 ± 2.8 ms; p = 0.0005, for males (p = 0.0066, and for females (p = 0.0208. Sleep deprivation reduced SSWT scores for the whole cohort in both ears [(right: BSL, 98.4 % ± 1.8 % vs. SD, 94.2 % ± 6.3 %. p = 0.0005(left: BSL, 96.7 % ± 3.1 % vs. SD, 92.1 % ± 6.1 %, p  Conclusion Sleep deprivation impairs RGDT and SSWT performance. These findings confirm that sleep deprivation has central effects that may impair performance in other areas of life.

Besseres Strafrecht?

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Sven Korzilius

2010-01-01

Full Text Available Rezensiertes Werk:Erich Buchholz, Strafrecht im Osten. Ein Abriss über die Geschichte des Strafrechts in der DDR (Edition Zeitgeschichte 37, Berlin: Homilius 2008, 661 S., ISBN 978-3-89706-857-5

Real Time Polymerase Chain Reaction : Perangkat Diagnostic Alternatif untuk Melacak Virus Nipah (REAL TIME POLYMERASE CHAIN REACTION : AN ALTERNATIVE DIAGNOSTIC TOOL TO DETECT NIPAH VIRUS

Directory of Open Access Journals (Sweden)

Indrawati Sendow

2014-05-01

Full Text Available Nipah is a dangerous zoonotic disease with a high social, economical and psychological impact. Fruitbat Pteropus sp. is one of the nipah virus  reservoir host. As the virus is categorized as a dangerous zoonoticdisease that cause fatal in human, all works related to live virus should be conducted in a laboratory withBSL4 facilities. The detection of nipah virus using real time PCR to replace virus isolastion can thereforebe conducted in a laboratory without BSL4 facilities. The results was further  confirmed at referencelaboratory at   Australian Animal Health Laboratory ( AAHL Geelong, Australia, indicated that nipahvirus can be detected in saliva of fruit bat P. vampyrus in Medan North Sumatera.

Privacy, werk en internet of things

NARCIS (Netherlands)

Van Der Sype, Yung Shin; Vedder, Anton

2016-01-01

Technologisch zijn ondernemingen nog niet klaar voor 3.0. Hoewel reeds heel wat technische snufjes in de onderneming binnensijpelen, staat de technologie nog niet op punt om al van een Internet of Things te spreken. Dit geeft ons de tijd om ons juridisch voor te bereiden op de opkomende

Veiligheidskleding voor werk op de weg.

NARCIS (Netherlands)

1968-01-01

This report contains a problem-analysis about safety clothes for workers on the road. Some of the results are: (1) The best colour if fluorescing orange. (2) The material must be transporting warmth and moisture. The material which are available today, are not satisfactory.

Hiv-bestrijding begint met GIS-werk

NARCIS (Netherlands)

Op de Coul, E. L. M.; Joore, I. K.; van sighem, A.; Bom, B. C. J.; Hillebregt, M.; Prins, J. M.; Geerlings, S. E.; van Bergen, J. E. A. M.

2017-01-01

To map regions of the Netherlands with high HIV prevalence for surveillance and prevention purposes. Information on numbers of HIV patients receiving clinical care on 31 December 2014 per postcode region was requested from the HIV monitoring foundation (SHM). These details were related to data from

Unverrichteter Sache

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Jani Kirov

2007-01-01

Full Text Available Rezensiertes Werk: Adriaan Lanni, Law and Justice in the Courts of Classical Athens, Cambridge: Cambridge University Press 2006, 210 S., ISBN-13 978-0-521-85759-8; ISBN-10 0-521-85759-7

Schattenboxen

Directory of Open Access Journals (Sweden)

Johannes Berchtold

2011-01-01

Full Text Available Rezensiertes Werk: Turan Kayaoğlu, Legal Imperialism. Sovereignty and Extraterritoriality in Japan, the Ottoman Empire, and China, New York: Cambridge University Press 2010, VIII, 237 p., ISBN 978-0-521-76591-6

Keim, Karl-Dieter, Das Fenster zum Raum : Traktat über die Erforschung sozialräumlicher Transformation / [rezensiert von] Helmut Klüter

OpenAIRE

Klüter, Helmut

2009-01-01

Rezensiertes Werk: Keim, Karl-Dieter: Das Fenster zum Raum : Traktat über die Erforschung sozialräumlicher Transformation / Karl-Dieter Keim. - Opladen : Leske + Budrich, 2003. - 171 S. : graph. Darst. - (Lehrtexte : Sozialwissenschaften) ISBN 3-8100-4050-9

Het Vietnam van Viet Thanh Nguyen [Bespreking van: V.T. Nguyen The sympathizer; V.T. Nguyen Nothing ever dies: Vietnam and the memory of war

NARCIS (Netherlands)

Kleinen, J.

2016-01-01

Over geen enkele Amerikaanse oorlog en de gevolgen daarvan zijn meer boeken geschreven dan over de Vietnamoorlog. En toch zijn we er nog lang niet over uitgeschreven. Terecht, getuige het verrassende werk van Viet Thanh Nguyen.

MILAGRO OBSERVATIONS OF MULTI-TeV EMISSION FROM GALACTIC SOURCES IN THE FERMI BRIGHT SOURCE LIST

International Nuclear Information System (INIS)

Abdo, A. A.; Linnemann, J. T.; Allen, B. T.; Chen, C.; Aune, T.; Berley, D.; Goodman, J. A.; Christopher, G. E.; Kolterman, B. E.; Mincer, A. I.; Nemethy, P.; DeYoung, T.; Dingus, B. L.; Hoffman, C. M.; Ellsworth, R. W.; Gonzalez, M. M.; Hays, E.; McEnery, J. E.; Huentemeyer, P. H.; Morgan, T.

2009-01-01

We present the result of a search of the Milagro sky map for spatial correlations with sources from a subset of the recent Fermi Bright Source List (BSL). The BSL consists of the 205 most significant sources detected above 100 MeV by the Fermi Large Area Telescope. We select sources based on their categorization in the BSL, taking all confirmed or possible Galactic sources in the field of view of Milagro. Of the 34 Fermi sources selected, 14 are observed by Milagro at a significance of 3 standard deviations or more. We conduct this search with a new analysis which employs newly optimized gamma-hadron separation and utilizes the full eight-year Milagro data set. Milagro is sensitive to gamma rays with energy from 1 to 100 TeV with a peak sensitivity from 10 to 50 TeV depending on the source spectrum and declination. These results extend the observation of these sources far above the Fermi energy band. With the new analysis and additional data, multi-TeV emission is definitively observed associated with the Fermi pulsar, J2229.0+6114, in the Boomerang pulsar wind nebula (PWN). Furthermore, an extended region of multi-TeV emission is associated with the Fermi pulsar, J0634.0+1745, the Geminga pulsar.

Waarom volwassenen met ADHD vaak te laat komen op afspraken – is het een beperking in de tijdwaarneming of het geheugen?

NARCIS (Netherlands)

Mette, Christian; Zielke, Annika; Groen, Yvonne

Volwassenen met aandachtstekortstoornis met hyperactiviteit (ADHD) hebben vaak moeite met tijdmanagement en het nakomen van afspraken. Een belangrijke functie voor tijdmanagement is tijdwaarneming, die weer samenhangt met de werking van het kortetermijn- en het werkgeheugen. De onderliggende

Absorption of formaldehyde in water

NARCIS (Netherlands)

Winkelman, Jozef Gerhardus Maria

2003-01-01

Deze dissertatie beschrijft theoretisch en experimenteel werk aan de absorptie van formaldehyde in water. Met resultaten hiervan zijn chemisch-technische modellen ontwikkeld voor de beschrijving en optimalisatie van industriële formaldehydeabsorbeurs. Deze samenvatting geeft eerst algemene

Digitalis en atriumfibrilleren anno 1985

NARCIS (Netherlands)

Meijler, F.L.; Tweel, I. van der

1985-01-01

In dit artikel worden enkele fundamentele aspecten van atriumfibrilleren en de rol van het atrioventriculaire geleidingssysteem daarbij besproken die ook van belang kunnen zijn voor de eerstelijnsgezondheidszorg, waarbij tevens aandacht wordt besteed aan de werking van digitalis.

Orienterend onderzoek naar de kwaliteit van champignonconserven

NARCIS (Netherlands)

Worp, van de H.H.M.; Herstel, H.

1981-01-01

Oriënterend onderzoek naar de kwaliteit van champignonconserven in verband met het in werking treden, per 1 januari 1982, van Verordening PGF 1981 Verduurzaamde Groenten. Vijf monsters champignonconserven werden onderzocht op etikettering, bijzondere kwaliteitsvoorschriften, de toevoegingen

en daar ook drie vertaalde gedigte van Giorgos Seferis opgeneem is ...

African Journals Online (AJOL)

waaraan Kavafis sy roem veral te danke het) nie, maar ook uit werk met 'n meer. histories beskoulike strekking (die tweede groot tema by Kavafis), asook gedigte wat nie tot die heel bekendstes van Kavafis behoort nie.

VS of the uppermost crust structure of the Campi Flegrei caldera (southern Italy) from ambient noise Rayleigh wave analysis

Science.gov (United States)

Costanzo, M. R.; Nunziata, C.; Strollo, R.

2017-11-01

Shear wave velocities (VS) are defined in the uppermost 1-2 km of the Campi Flegrei caldera through the non-linear inversion of the group velocity dispersion curves of fundamental-mode Rayleigh waves extracted from ambient noise cross-correlations between two receivers. Noise recordings, three months long, at 12 seismic stations are cross-correlated between all couples of stations. The experiment provided successful results along 54 paths (inter-stations distance), of which 27 sampled a depth > 1 km. VS contour lines are drawn from 0.06 km b.s.l. to 1 km depth b.s.l. and show difference between the offshore (gulf of Pozzuoli and coastline) and the onshore areas. At 0.06 km b.s.l., the gulf of Pozzuoli and the coastline are characterized by VS of 0.3-0.5 km/s and of 0.5-0.7 km/s, respectively. Such velocities are typical of Neapolitan pyroclastic soils and fractured or altered tuffs. The inland shows VS in the range 0.7-0.9 km/s, typical of Neapolitan compact tuffs. Velocities increase with depth and, at 1 km depth b.s.l., velocities lower than 1.5 km/s are still present in the gulf and along the coastline while velocities higher than 1.9 km/s characterize the eastern sector (grossly coincident with the Neapolitan Yellow Tuff caldera rim), the S. Vito plain and the area between Solfatara and SW of Astroni. Such features are much more evident along two cross-sections drawn in the offshore and onshore sectors by integrating our VS models with literature data. Our models join previous noise cross-correlation studies at greater scale at depths of 0.7-0.8 km, hence the picture of the Campi Flegrei caldera is shown up to a depth of 15 km. VS of about 1.7 km/s, corresponding to compression velocities (VP) of about 3 km/s (computed by using the VP/VS ratio resulted in the inversion), are found at depths of 1.1 km, in the centre of the gulf of Pozzuoli, and at a depth of about 0.7 km b.s.l. onshore. An increment of VS velocity ( 1.9-2.0 km/s) is locally observed onshore

NATbox: a network analysis toolbox in R.

Science.gov (United States)

Chavan, Shweta S; Bauer, Michael A; Scutari, Marco; Nagarajan, Radhakrishnan

2009-10-08

There has been recent interest in capturing the functional relationships (FRs) from high-throughput assays using suitable computational techniques. FRs elucidate the working of genes in concert as a system as opposed to independent entities hence may provide preliminary insights into biological pathways and signalling mechanisms. Bayesian structure learning (BSL) techniques and its extensions have been used successfully for modelling FRs from expression profiles. Such techniques are especially useful in discovering undocumented FRs, investigating non-canonical signalling mechanisms and cross-talk between pathways. The objective of the present study is to develop a graphical user interface (GUI), NATbox: Network Analysis Toolbox in the language R that houses a battery of BSL algorithms in conjunction with suitable statistical tools for modelling FRs in the form of acyclic networks from gene expression profiles and their subsequent analysis. NATbox is a menu-driven open-source GUI implemented in the R statistical language for modelling and analysis of FRs from gene expression profiles. It provides options to (i) impute missing observations in the given data (ii) model FRs and network structure from gene expression profiles using a battery of BSL algorithms and identify robust dependencies using a bootstrap procedure, (iii) present the FRs in the form of acyclic graphs for visualization and investigate its topological properties using network analysis metrics, (iv) retrieve FRs of interest from published literature. Subsequently, use these FRs as structural priors in BSL (v) enhance scalability of BSL across high-dimensional data by parallelizing the bootstrap routines. NATbox provides a menu-driven GUI for modelling and analysis of FRs from gene expression profiles. By incorporating readily available functions from existing R-packages, it minimizes redundancy and improves reproducibility, transparency and sustainability, characteristic of open-source environments

Kaizen - continuous improvement of high voltage products; Kaizen - kontinuierliche Verbesserung bei Hochspannungsprodukten

Energy Technology Data Exchange (ETDEWEB)

Schwarz, M. [ABB Calor Emag Schaltanlagen AG, Hanau-Grossauheim (Germany); Goessmann, T. [ABB Calor Emag Schaltanlagen AG, Mannheim (Germany)

1999-07-12

In the actual global competition only the company can survive who cares for the continuous improvement of all business activities. The ABB Calor Emag Schaltanlagen AG at his production site in Hanau-Grossauheim has installed a specific improvement programm called KVP what is based on the ideas of Kaizen. Aim is the improvement of processes, mainly in production, concerning quality, dates, costs and environment by activating all colleagues. (orig.) [Deutsch] Im heutigen globalen Wettbewerb kann sich nur der behaupten, der sich kontinuierlich in allen Unternehmensbereichen weiterentwickelt. Die ABB Calor Emag Schaltanlagen AG hat in ihrem Werk Hanau-Grossauheim nach den Ideen des Kaizen ein werkspezifisches Programm zur kontinuierlichen Verbesserung der Prozesse in der Fertigung eingefuehrt. Ziel ist die stetige Verbesserung von Fertigungsparametern, wie Qualitaet, Termine, Kosten und Umwelt unter Einbeziehung aller Mitarbeiter. (orig.)

Een hoge werkdruk sluipt er in

NARCIS (Netherlands)

Hulst, van der M.

2005-01-01

De werkdruk op het melkveebedrijf neemt toe. Boeren raken aan de grenzen van hun kunnen, waardoor de lol in het werk afneemt. Bespreking van de arbeidsinzet op het bedrijf in een studiegroep leidt tot efficiënter werken

Gewenst beleid tegen ongewenst gedrag : onveiligheid binnen de organisatie kan leiden tot ziekteverzuim

NARCIS (Netherlands)

Dalen, E.J. van; Nuyens, M.

2005-01-01

Indimidatie en agressie en geweld op het werk kunnen leiden tot gevoelens van onveiligheid en ziekteverzuim. Bepalingen in de Arbowet hebben onvoldoende effect op beleidsvorming ter voorkoming van ongewenste omgangsvormen. Goede praktijkvoorbeelden van beleid tegen ongewenst gedrag kunnen

kant geveg het) aan sv lesers vaor Ie. Die deel sol" aFgesluit word ...

African Journals Online (AJOL)

Uggla se verslag oor die herdenkingsbveenkomste von die slog von. MogersFontein (Stockholm, 1926). Op p. ix von die publikasie verskvn 'n bibliograFie von bestaande werke in AFrikoons, Engels en. Nederlands wat oandog oan die lotgevalle ...

Medezeggenschap bij DSM: Limburg 1946-2011

NARCIS (Netherlands)

Buitelaar, W.

2011-01-01

"Doing Something Meaningful", zo kenmerkte DSM-bestuursvoorzitter Feike Sijbesma de activiteiten van het concern (NRC, 23 februari 2011). Dat geldt in onderstaande terugblik over de periode 1946-2011 evenzeer voor het werk van de medezeggenschappers van DSM Limburg.

Bounding Accident Analysis for LLNL BSL-3 Facility

Energy Technology Data Exchange (ETDEWEB)

Johnson, Mark [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2010-09-14

The conclusion of this evaluation is that the consequence estimates in the EA can be reproduced using a public-accessible Gaussian plume-dispersion model and conservative modeling assumptions consistent with the accident scenario postulated in the EA. Also, the potential consequences to the public for the postulated accident would be far below the minimum infectious dose of one organism.

Neue Klassik-CDs

Index Scriptorium Estoniae

2001-01-01

Firma Antes plaatide seas "Eesti portreed. Werke für Flöte und Gitarre", "Kangro. Klavierkonzert Nr.2"; Deutsche Grammophon'i plaat "Steinberg dir, N. Järvi"; Globe plaat "Tanejev. The Twelve Choruses op. 27", dir. T. Kaljuste

Een empirisch onderzoek naar de rol van de openbare apotheker in de geneesmiddelenvoorziening

NARCIS (Netherlands)

A. Mantel; B. Wierenga (Berend)

1988-01-01

textabstractIn het kader van het in opdracht van het Ministerie van Welzijn, Volksgezondheid en Cultuur verrichte wetenschappelijk onderzoek 'De Nederlandse geneesmiddelenmarkt in observatie' is door een projectgroep een studie verricht naar structuur en werking van de Nederlandse extramurale

Inelastic processes in atomic collisions involving ground state and laser-prepared atoms

NARCIS (Netherlands)

Planje, Willem Gilles

1999-01-01

In dit proefschrift worden experimenten beschreven waarbij ionen of atomen met een bepaalde snelheid op een ensemble van doelwitatomen worden gericht. Wanneer twee deeltjes elkaar voldoende genaderd hebben, vindt er wissel- werking plaats waarbij allerlei processen kunnen optreden. Deze

Implementation of a personnel reliability program as a facilitator of biosafety and biosecurity culture in BSL-3 and BSL-4 laboratories.

Science.gov (United States)

Higgins, Jacki J; Weaver, Patrick; Fitch, J Patrick; Johnson, Barbara; Pearl, R Marene

2013-06-01

In late 2010, the National Biodefense Analysis and Countermeasures Center (NBACC) implemented a Personnel Reliability Program (PRP) with the goal of enabling active participation by its staff to drive and improve the biosafety and biosecurity culture at the organization. A philosophical keystone for accomplishment of NBACC's scientific mission is simultaneous excellence in operations and outreach. Its personnel reliability program builds on this approach to: (1) enable and support a culture of responsibility based on human performance principles, (2) maintain compliance with regulations, and (3) address the risk associated with the insider threat. Recently, the Code of Federal Regulations (CFR) governing use and possession of biological select agents and toxins (BSAT) was amended to require a pre-access suitability assessment and ongoing evaluation for staff accessing Tier 1 BSAT. These 2 new requirements are in addition to the already required Federal Bureau of Investigation (FBI) Security Risk Assessment (SRA). Two years prior to the release of these guidelines, NBACC developed its PRP to supplement the SRA requirement as a means to empower personnel and foster an operational environment where any and all work with BSAT is conducted in a safe, secure, and reliable manner.

Kansrijk ; verbeteren van Leerlingprestaties door schoolontwikkeling

NARCIS (Netherlands)

Houtveen, A.A.M.; Kuijpers, J.M.; Mijs, T.J.E.

2004-01-01

Zes onderwijskansenscholen zijn onder begeleiding van het Christelijk Pedagogische Studiecentrum (CPS) hard aan het werk om de kwaliteit van hun onderwijs te verbeteren. Er zijn vier hoofdoorzaken aan te wijzen voor het achterblijven van de prestaties op onderwijskansenscholen. Deze zijn: een

Case note: EHRM (Grand Chamber) (zaaknr. 16354/06, LJN BX9103: Mouvement Raëlien Suisse/Zwitserland: verbod verspreiding posters is niet in strijd met de vrijheid van meningsuiting)

NARCIS (Netherlands)

Dommering, E.J.

2014-01-01

Mensenrechten. Vrijheid van meningsuiting. Weigering van vergunning voor het ophangen van posters van organisatie die contact met buitenaardse wezens nastreeft. Uiting is eerder commercieel dan politiek van aard wegens ‘bekerende’ werking. Vanwege vermelding website moet ook inhoud daarvan worden

Over granulosaceltumoren en hun hormonalen invloed op uterus en tuba

NARCIS (Netherlands)

Kleijn, Christiaan Hendrik Frans

1937-01-01

In dit proefschrift is nagegaan de histologie van de granulosacelrumoren en hun hormonale werking. De granulosaceltumoren danken hun naam aan de overeenkomst in vorm en structuur tusschen hun cellen en granulosacellen. Deze overeenkomst gaat zeer ver: aile differentiatiestadia, die de granulosa

Kui suur on maailmakirjandus? / Cornelius Hasselblatt

Index Scriptorium Estoniae

Hasselblatt, Cornelius, 1960-

2015-01-01

Arvustus: Aija Sakova-Merivee. Ausgraben und Erinnern. Denkbilder des Erinnerns und der moralischen Zeugenschaft im Werk von Ene Mihkelson und Christa Wolf. Tartu : University of Tartu Press, c2014. (Dissertationes litterarum et contemplationis comparativae Universitatis Tartuensis, 1406-913X ; 13)

Waar blijven de nieuwe Pythagorassen en Archimedessen? : met potlood, papier, liniaal, passer èn gummetje rechtgeleidingen construeren

NARCIS (Netherlands)

Dijksman, E.A.

1994-01-01

Rekenmachines hebben het werktuigbouwkundig onderwijs zeer nadelig beinvloed. De digitale (algebraische) werking ervan heeft de meetkunde vèr onderuit gehaald. Werktuigbouwkundige studenten weten bijna niets meer af van de eigenschappen van een cirkel, cirkelbundels met een machtlijn, of van Iijnen

Experimental improvisation practise and notation. Addenda 2000-

DEFF Research Database (Denmark)

Bergstrøm-Nielsen, Carl

Addenda to Experimental improvisation practise and notation (please see this title for more information!) Stichwörter: experimentelle Musik, offenes Werk, grafische Notation, musikalische Notation, musikalische Aufführungspraxis, freie Improvisation, Musikpädagogik, Geschichte der Musik, Musikäst...

Nieuws uit het westen : meerouderschap en draagmoederschap in British Columbia

NARCIS (Netherlands)

Vonk, M.J.

2016-01-01

In 2013 is in de Canadese provincie British Columbia nieuwe familierechtwetgeving in werking getreden: de Family Law Act, met daarin een regeling voor draagmoederschap, meerouderschap en meeroudergezag. Gezien de discussie in Nederland over deze onderwerpen en de instelling van de Staatscommissie

Spiegelkunde

Directory of Open Access Journals (Sweden)

Pia Letto-Vanamo

2005-01-01

Full Text Available Rezensiertes Werk:Jørn Øyrehagen Sunde, Speculum legale – rettsspegelen. Ein introduksjon til den norske rettskulturen si historie i eit europeisk perspektiv, Bergen: Fagbokforlaget Vigmostad & Bjørke 2005, 409 S., ISBN 82-450-0090-6

Ambtscriminaliteit aangegeven? : Een onderzoek naar het opvolgen van en kennis over de wettelijke verplichting tot aangifte van artikel 162 Sv misdrijven

NARCIS (Netherlands)

Vries Robbé, E. de; Cornelissens, A.; Ferwerda, H.

2008-01-01

Dit is een onderzoek naar de werking van de aangifteplicht bij ambtscriminaliteit (art 162 Sv). Het gaat dan bijvoorbeeld om het aannemen van steekpenningen en misdrijven waarbij ambtenaren een bijzondere ambtsplicht schenden. De aangifteplicht raakt de klokkenluidersregeling en maakt onderdeel uit

Stapelbouw

NARCIS (Netherlands)

Vissers, M.M.J.; Vlaar, G.J.; Hofkes, xx; Brinksma, xx; Zimmermann, xx; Van Tol, xx; Flapper, xx; Bonebakker, xx

2006-01-01

Men zou kunnen zeggen dat de benaming van een bouwmethode voortkomt uit de verwerkingsvorm van de bouwmaterialen en producten die worden gebruikt voor de hoofddraagstructuur (casco) en vooral daarvan het opgaande werk. Met andere woorden: de wijze waarop de productiemiddelen (materiaal, materieel en

X-ray and neutron diffraction studies of some liquid alkali metals and alloys

NARCIS (Netherlands)

Huijben, Martinus Johannes

1978-01-01

Het in dit proefschrift beschreven onderzoek is een logische consequentie van de probleemstelling die ten grondslag ligt aan het werk binnen de werkgroep "Vloeibare Metalen"van het laboratorium voor Vaste Stof Fysica, nl. de interpretatie van de eigenschappen van eenvoudige vloeibare metalen en

Tuumafüüsik möllab BMW-s nagu jaksab / Toomas Pärna

Index Scriptorium Estoniae

Pärna, Toomas, 1966-

2004-01-01

Bayerische Motoren Werke (BMW) brändi maine kujundamisest, BMW juhi Helmut Panke poolt ärgitatud pidevast tootearendusest ettevõttes ning kiire arenguga seotud võimalikest riskidest. Lisa: BMW-de müük Eestis Vt. samas: BMW luksuskupee müüdud

Social inclusion in diverse work settings

NARCIS (Netherlands)

Jansen, Wiebren

2015-01-01

Het ervaren van sociale inclusie op het werk is essentieel voor het welbevinden en presteren van werknemers. Echter, terwijl inclusie relatief gemakkelijk te bewerkstelligen is wanneer collega’s demografisch gezien op elkaar lijken, is dit moeilijker wanneer collega's sterk van elkaar verschillen.

Optimization of ultrasonic extraction of mycelial polysaccharides ...

African Journals Online (AJOL)

ajl yemi

2011-11-28

Nov 28, 2011 ... air dryer and ground into powder by a muller (A11 basic, ZKA-. WERKE ..... of regression equation were taken and made to be zero. Calculating the .... ia of Dietary Supplements New York: Marcel Dekker. pp. 665-679. Hou XJ ...

Deutsche Fremdwortlexikografie zwischen 1800 und 2007

DEFF Research Database (Denmark)

Heier, Anke

daran, dass in ihnen ein Wortschatzbereich erfasst, beschrieben, kommentiert, zum Teil auch diskutiert wird, der in der Öffentlichkeit bis heute besondere Aufmerksamkeit erfährt. Bisher fokussierten wissenschaftliche Analysen jedoch vor allem auf ältere und puristische Werke. Diese Untersuchung nimmt...

'Je moeder leert je wie je vijanden zijn'

NARCIS (Netherlands)

Makkink, C.; Parmentier, H.K.

2014-01-01

Via de voeding van ouderdieren kan de werking van het immuunsysteem van de nakomelingen worden beïnvloed. Het is een uitdaging om interventies te vinden die het immuunsysteem van landbouwhuisdieren optimaliseren, zo luidde de conclusie tijdens de Feed4Foodure-themamiddag.

De bezielde zakelijkheid van M. Revis : Over het oeuvre van een vergeten auteur

NARCIS (Netherlands)

Anten, J.H.M.

1990-01-01

Feiten, cijfers en beschrijvingen van manoeuvres in de handels- en geldwereld spelen een belangrijke rol in het werk van M. Revis. Zijn fascinatie voor het maatschappelijkeconomisch leven enerzijds, en zijn protest tegen sociale misstanden anderzijds, maken hem tot een opmerkelijk auteur. In dit

Sexual orientation and the workplace experience

NARCIS (Netherlands)

Lisette Kuyper

2013-01-01

Original title: Seksuele oriëntatie en werk Large-scale studies are regularly held in the Netherlands to monitor the employment situation and work experience of employees. However, some groups of employees receive insufficient attention in these studies. The Netherlands Institute for Social

South African Journal of Child Health - Vol 4, No 4 (2010)

African Journals Online (AJOL)

Diffuse bony involvement in disseminated BCG disease in a patient with possible severe combined immune deficiency (SCID) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. N Khan, I van de Werke, F Ismail, 116-118 ...

Equal Opportunities and Ethnic Inequality in European Labour Markets : Discrimination, Gender and Policies of Diversity

NARCIS (Netherlands)

2009-01-01

De noodzaak om de arbeidsmarkt mechanismen in postindustriële westerse samenlevingen te analyseren is urgent. Ondanks wetten en beleidsmaatregelen die op Europees, nationaal en lokaal niveau worden ontwikkeld, lijdt het zoeken van werk door immigranten en etnische minderheden nog steeds onder

Rollencombinaties

NARCIS (Netherlands)

A.C. Liefbroer (Aart); P.A. Dykstra (Pearl)

2001-01-01

textabstractMannen verdienen het inkomen voor het gezin, vrouwen doen het huishoudelijk werk en verzorgen de kinderen. Dit is het beeld dat bestaat van het standaardgezin. Maar zo traditioneel-eenzijdig hebben de Nederlandse huishoudens de taken niet verdeeld: het standaardgezin past slechts bij

Locus: mede-ontwikkelaar van inclusieve arbeidsorganisaties

NARCIS (Netherlands)

Beukema, Leni; de Lange, Annet; Wielenga-Meijer, Etty; Duijker, Theo; Hanstede, Bram

2018-01-01

in deze bijdrage wordt Locus beschreven, een netwerk waarin publieke partijen en grote, landelijk opererende bedrijven samenwerken om mensen met een afstand tot de arbeidsmarkt duurzaam aan het werk te helpen. Het hoofdstuk start met de ontstaansgeschiedenis en benadering van Locus. Vervolgens wordt

The penicillin-binding protein 4 of Escherichia coli : primary structure, biochemical and genetic studies

NARCIS (Netherlands)

Mottl, Harald

1992-01-01

De ß-lactam antibiotica ("de penicillines") zijn zowel in medisch als ecomisch opzicht de belangrijkste groep antibiotica: De werking van deze antibiotica berust op verstoring van de synthese van de bacteriele celwand. De doeleiwitten van deze antibiotica worden penicillin-binding proteins, kortweg

Differences in mental health among young adults with borderline personality symptoms of various severities

Directory of Open Access Journals (Sweden)

Wei-Hsin Lu

2018-04-01

Full Text Available Purpose: This study examined the differences in mental health and behavioral problems among young adults with borderline personality symptoms of various severities. Methods: 500 college students participated in this study. Borderline personality symptoms were evaluated using the Taiwanese version of the Borderline Symptom List (BSL-23. Mental health problems were assessed using the Symptom Checklist-90-Revised Scale. Suicidality and other behavioral problems were assessed using questions from the epidemiological version of the Kiddie Schedule for Affective Disorders and Schizophrenia and BSL-23 Supplement. According to the distribution of BSL-23 scores at the 25th, 50th, and 75th percentiles, the participants were divided into 4 groups: No/Mild, Moderate, Severe, and Profound. Analysis of variance and the chi-square test were used to compare mental health and behavioral problems among the 4 groups. Results: All mental health problems differed significantly among the 4 groups. The severity of nearly all mental health problems increased with that of borderline personality symptoms. The proportions of most behavioral problems differed significantly among the 4 groups. The Profound group was more likely to have behavioral problems than the other 3 groups. Conclusion: Young adults who had more severe borderline personality symptoms had more severe mental health and behavioral problems. Keywords: Borderline personality, Mental health, Suicidality

Shedding Light on Filovirus Infection with High-Content Imaging

Directory of Open Access Journals (Sweden)

Rekha G. Panchal

2012-08-01

Full Text Available Microscopy has been instrumental in the discovery and characterization of microorganisms. Major advances in high-throughput fluorescence microscopy and automated, high-content image analysis tools are paving the way to the systematic and quantitative study of the molecular properties of cellular systems, both at the population and at the single-cell level. High-Content Imaging (HCI has been used to characterize host-virus interactions in genome-wide reverse genetic screens and to identify novel cellular factors implicated in the binding, entry, replication and egress of several pathogenic viruses. Here we present an overview of the most significant applications of HCI in the context of the cell biology of filovirus infection. HCI assays have been recently implemented to quantitatively study filoviruses in cell culture, employing either infectious viruses in a BSL-4 environment or surrogate genetic systems in a BSL-2 environment. These assays are becoming instrumental for small molecule and siRNA screens aimed at the discovery of both cellular therapeutic targets and of compounds with anti-viral properties. We discuss the current practical constraints limiting the implementation of high-throughput biology in a BSL-4 environment, and propose possible solutions to safely perform high-content, high-throughput filovirus infection assays. Finally, we discuss possible novel applications of HCI in the context of filovirus research with particular emphasis on the identification of possible cellular biomarkers of virus infection.

Communication and computing technology in biocontainment laboratories using the NEIDL as a model.

Science.gov (United States)

McCall, John; Hardcastle, Kath

2014-07-01

The National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, is a globally unique biocontainment research facility housing biosafety level 2 (BSL-2), BSL-3, and BSL-4 laboratories. Located in the BioSquare area at the University's Medical Campus, it is part of a national network of secure facilities constructed to study infectious diseases of major public health concern. The NEIDL allows for basic, translational, and clinical phases of research to be carried out in a single facility with the overall goal of accelerating understanding, treatment, and prevention of infectious diseases. The NEIDL will also act as a center of excellence providing training and education in all aspects of biocontainment research. Within every detail of NEIDL operations is a primary emphasis on safety and security. The ultramodern NEIDL has required a new approach to communications technology solutions in order to ensure safety and security and meet the needs of investigators working in this complex building. This article discusses the implementation of secure wireless networks and private cloud computing to promote operational efficiency, biosecurity, and biosafety with additional energy-saving advantages. The utilization of a dedicated data center, virtualized servers, virtualized desktop integration, multichannel secure wireless networks, and a NEIDL-dedicated Voice over Internet Protocol (VoIP) network are all discussed. © 2014 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

Sarah Dellmann: Widerspenstige Körper. Körper, Kino, Sprache und Subversion in Tod Brownings FREAKS und Filmen mit Lon Chaney. Marburg: Schüren Verlag 2009.

Directory of Open Access Journals (Sweden)

Fabian Tietke

2010-11-01

Full Text Available Im vorliegenden Band werden Filme des in den 1920er und 1930er Jahren sehr erfolgreichen Regisseurs Tod Browning analysiert, insbesondere sein heute bekanntestes Werk Freaks. Mithilfe historischer Kontextualisierungen und eines filmwissenschaftlichen Instrumentariums untersucht Dellmann die These, dass sich in diesem Werk Spuren eines heute verloren gegangenen Körperverständnisses finden lassen – vor allem andere Repräsentationen von Behinderung und behinderten männlichen Körpern.The present anthology analyzes several movies of the director Tod Browning (who was very successful in the 1920s and 1930s, particularly the movie Freaks which, today, is his most well-known work. Using historical contextualizations and a Film Studies background, Dellmann explores the thesis that this work shows traces of an understanding of the body that today no longer exist, above all the representation of disabilities and disabled male bodies.

78 FR 9828 - Establishment of User Fees for Filovirus Testing of Nonhuman Primate Liver Samples

Science.gov (United States)

2013-02-12

... specifically for a ``filovirus testing facility'' because laboratories, especially the Biosafety Level 4 (BSL-4... a price that may be below standard commercial market fees, or free. The fee HHS/CDC intends to...

Site specific information in site selection

International Nuclear Information System (INIS)

Aeikaes, T.; Hautojaervi, A.

1998-01-01

The programme for the siting of a deep repository for final disposal of spent nuclear fuel was started already in 1983 and is carried out today by Posiva Oy which continues the work started by Teollisuuden Voima Oy. The programme aims at site selection by the end of the year 2000. The programme has progressed in successive interim stages with defined goals. After an early phase for site identification, five sites were selected in 1987 for preliminary site characterisation. Three of these were selected and judged to be best suited for the more detailed characterisation in 1992. An additional new site was included into the programme based on a separate feasibility study in the beginning of 1997. Since the year 1983 several safety assessments together with technical plans of the facility have been completed. When approaching the site selection the needs for more detailed consideration of the site specific properties in the safety assessment have been increased. The Finnish regulator STUK has published a proposal for general safety requirements for the final disposal of spent nuclear fuel in Finland. This set of requirements has been projected to be used in conjunction of the decision making by the end 2000. Based on the site evaluation all sites can provide a stable environment and there is evidence that the requirements for the longevity of the canister can be fulfilled at each site. In this manner the four candidate sites do not differ too much from each other. The main difference between the sites is in the salinity of the deep groundwater. The significance of differences in the salinity for the long-term safety cannot be defined yet. The differences may contribute to the discussion of the longevity of the bentonite buffer and also to the modelling of the groundwater flow and transport. The use of the geosphere as a transport barrier is basically culminated on the questions about sparse but fast flow routes and 'how bad channeling can be'. To answer these questions

Endophytic Fungi from Frankincense Tree Improves Host Growth and Produces Extracellular Enzymes and Indole Acetic Acid.

Directory of Open Access Journals (Sweden)

Abdul Latif Khan

Full Text Available Boswellia sacra, an economically important frankincense-producing tree found in the desert woodlands of Oman, is least known for its endophytic fungal diversity and the potential of these fungi to produce extracellular enzymes and auxins. We isolated various fungal endophytes belonging to Eurotiales (11.8%, Chaetomiaceae (17.6%, Incertae sadis (29.5%, Aureobasidiaceae (17.6%, Nectriaceae (5.9% and Sporomiaceae (17.6% from the phylloplane (leaf and caulosphere (stem of the tree. Endophytes were identified using genomic DNA extraction, PCR amplification and sequencing the internal transcribed spacer regions, whereas a detailed phylogenetic analysis of the same gene fragment was made with homologous sequences. The endophytic colonization rate was significantly higher in the leaf (5.33% than the stem (0.262%. The Shannon-Weiner diversity index was H' 0.8729, while Simpson index was higher in the leaf (0.583 than in the stem (0.416. Regarding the endophytic fungi's potential for extracellular enzyme production, fluorogenic 4-methylumbelliferone standards and substrates were used to determine the presence of cellulases, phosphatases and glucosidases in the pure culture. Among fungal strains, Penicillum citrinum BSL17 showed significantly higher amounts of glucosidases (62.15±1.8 μM-1min-1mL and cellulases (62.11±1.6 μM-1min-1mL, whereas Preussia sp. BSL10 showed significantly higher secretion of glucosidases (69.4±0.79 μM-1min-1mL and phosphatases (3.46±0.31μM-1min-1mL compared to other strains. Aureobasidium sp. BSS6 and Preussia sp. BSL10 showed significantly higher potential for indole acetic acid production (tryptophan-dependent and independent pathways. Preussia sp. BSL10 was applied to the host B. sacra tree saplings, which exhibited significant improvements in plant growth parameters and accumulation of photosynthetic pigments. The current study concluded that endophytic microbial resources producing extracellular enzymes and auxin

Endophytic Fungi from Frankincense Tree Improves Host Growth and Produces Extracellular Enzymes and Indole Acetic Acid.

Science.gov (United States)

Khan, Abdul Latif; Al-Harrasi, Ahmed; Al-Rawahi, Ahmed; Al-Farsi, Zainab; Al-Mamari, Aza; Waqas, Muhammad; Asaf, Sajjad; Elyassi, Ali; Mabood, Fazal; Shin, Jae-Ho; Lee, In-Jung

2016-01-01

Boswellia sacra, an economically important frankincense-producing tree found in the desert woodlands of Oman, is least known for its endophytic fungal diversity and the potential of these fungi to produce extracellular enzymes and auxins. We isolated various fungal endophytes belonging to Eurotiales (11.8%), Chaetomiaceae (17.6%), Incertae sadis (29.5%), Aureobasidiaceae (17.6%), Nectriaceae (5.9%) and Sporomiaceae (17.6%) from the phylloplane (leaf) and caulosphere (stem) of the tree. Endophytes were identified using genomic DNA extraction, PCR amplification and sequencing the internal transcribed spacer regions, whereas a detailed phylogenetic analysis of the same gene fragment was made with homologous sequences. The endophytic colonization rate was significantly higher in the leaf (5.33%) than the stem (0.262%). The Shannon-Weiner diversity index was H' 0.8729, while Simpson index was higher in the leaf (0.583) than in the stem (0.416). Regarding the endophytic fungi's potential for extracellular enzyme production, fluorogenic 4-methylumbelliferone standards and substrates were used to determine the presence of cellulases, phosphatases and glucosidases in the pure culture. Among fungal strains, Penicillum citrinum BSL17 showed significantly higher amounts of glucosidases (62.15±1.8 μM-1min-1mL) and cellulases (62.11±1.6 μM-1min-1mL), whereas Preussia sp. BSL10 showed significantly higher secretion of glucosidases (69.4±0.79 μM-1min-1mL) and phosphatases (3.46±0.31μM-1min-1mL) compared to other strains. Aureobasidium sp. BSS6 and Preussia sp. BSL10 showed significantly higher potential for indole acetic acid production (tryptophan-dependent and independent pathways). Preussia sp. BSL10 was applied to the host B. sacra tree saplings, which exhibited significant improvements in plant growth parameters and accumulation of photosynthetic pigments. The current study concluded that endophytic microbial resources producing extracellular enzymes and auxin could

What employers may learn from English higher education institutions: A fortigenic approach to occupational stress

Directory of Open Access Journals (Sweden)

M. Y. Tytherleigh

2003-10-01

Full Text Available Whilst there is no denying that levels of occupational stress in staff working in universities and colleges are increasing, academic staff, in particular, continue to maintain a level of satisfaction from their jobs. A stratified random sample of staff working in 14 higher education institutions in England was used. The results showed that, whilst commitment was lower and levels of occupational stress were significantly higher with regard to work relationships, control and resources and communication, compared to the normative data, staff reported significantly lower levels of stress relating to work-life balance, overload, and job dissatisfaction. Compared to normative data, participants reported significantly lower levels of physical ill-health and psychological outcomes of stress. The results support previous findings identifying a protective effect of job satisfaction against the negative consequences of workplace stress. Opsomming Terwyl dit nie ontken word dat die vlak van werkstres van personeel wat in universiteite en kolleges werk, verhoog nie, ervaar akademiese personeel steeds tevredenheid met hul werk. ’n Gestratifiseerde ewekansige steekproef van personeel wat by 14 hoër opvoedkundige instellings in Engeland werk, is geneem. Die resultate het aangetoon dat hoewel verbondenheid laer en werkstres beduidend hoër was ten opsigte van werksverhoudinge, kontrole en bronne en kommunikasie vergeleke met normatiewe data, personeel beduidend laer vlakke van stres ten opsigte van werklewe balans, oorlading en werkstevredenheid getoon het. Deelnemers het ook beduidend laer vlakke van fisieke ongesondheid en psigologiese uitkomstes van stres gerapporteer. Die resultate ondersteun vorige bevindings wat ’n beskermende effek van werkstevredenheid teen die negatiewe uitkomstes van stres identifiseer.

Site organization and site arrangement

International Nuclear Information System (INIS)

Boissonnet, B.; Macqueron, J.F.

1976-01-01

The present paper deals with criteria for the choice of a production unit or power plant site, the organization and development of a site in terms of its particular characteristics and takes into account personnel considerations in site organizations as well as the problem of integrating the architecture into the environment. (RW) [de

In vitro cultivation of Cryptosporidium parvum. A literature survey

NARCIS (Netherlands)

Schets FM; Leenen EJTM; MGB

1998-01-01

In vivo en in vitro modellen voor kweek van Cryptosporidium geven informatie over de infectiviteit van oocysten in ruw water en drinkwater en kunnen de identificatie van middelen met een anticryptosporidiele werking vereenvoudigen. In vivo modellen zijn echter duur, onpractisch en niet in elk

3D Printing verbindt Fontys Instituten : De basis voor een verdere samenwerking

NARCIS (Netherlands)

Drs. Ing. Ricardo Abdoel

2015-01-01

De wereld verandert in een razend tempo. Technologische ontwikkelingen hebben een grote impact op mens en maatschappij. Het verandert niet alleen onze manier van werken maar ook onze manier van leven. Steeds meer disciplines hanteren technologie als basis om in een professionele omgeving het werk

Carbohydrates : more than meets the eye

NARCIS (Netherlands)

Lopez-Bautista, Cesar

2012-01-01

Biofysica van koolhydraten op moleculair niveau Het proefschrift van César López Bautista onthult belangrijke aspecten van de biofysica van koolhydraten op moleculair niveau. Zijn werk laat zien hoe ‘state of the art’ moleculaire dynamica benaderingen diepere inzichten kunnen geven in het

How BMW Is Defusing the Demographic Time Bomb

NARCIS (Netherlands)

C.H. Loch (Christoph); F.J. Sting (Fabian); N. Bauer (Nikolaus); H. Mauermann (Helmut)

2010-01-01

textabstractThe article focuses on how the German car manufacturer, Bayerische Motoren Werke AG or BMW, is managing the effects of population aging on the industry. The redesign of BMW's factories to accommodate older workers and increase productivity is mentioned. Research on a pilot production

Insulin sensitivity : modulation by the gut-brain axis

NARCIS (Netherlands)

Heijboer, Annemieke Corine

2006-01-01

Er zijn steeds meer aanwijzingen dat neuropeptiden in de hypothalamus en maagdarmhormonen die hun werking hebben op de hypothalamus en betrokken zijn bij de regulatie van voedselinname, ook betrokken zouden kunnen zijn bij de regulatie van insuline gevoeligheid. Daarom hebben we eerst de effecten

Imidacloprid of niet? (interview met Sjef van der Steen)

NARCIS (Netherlands)

Kleis, R.; Steen, van der J.J.M.

2014-01-01

Is bijensterfte het werk van neonicotinoïden? Ja, zeggen en denken velen. Volgens hen zijn de neo’s rechtstreeks verantwoordelijk voor de hoge sterfte onder bijen. Nee, toont Wagenings onderzoek aan. Intussen lijkt het met de sterfte voorzichtig de goede kant op te gaan.

Adolf Mayer (1843-1942) en zijn betekenis voor de Virologie als wetenschap

NARCIS (Netherlands)

Vlak, J.M.

2007-01-01

In 2007 is het 125 jaar geleden dat Adolf Mayer voor het eerst zijn baanbrekend werk over het besmettelijk karakter van mozaiekziekte van tabak publiceerde (Mayer, 1882). Deze publicatie, in het Nederlands, in het Groningse Tijdschrift voor Landbouwkunde, markeert het begin van de virologie als

A. Feitsma, Tussen Hemsterhuis en Grimm. Joast Hiddes Halbertsma als taalkundige

NARCIS (Netherlands)

van der Geest, E.; van der Kuip, F.J.; Noordegraaf, J.

2012-01-01

Leven en werk van de taalkundige, schrijver en predikant Joast Hiddes Halbertsma 1789-1869) hebben steeds opnieuw de aandacht weten te trekken, zowel in Friesland als daarbuiten. In de jaren 1994-2003 heeft Tony Feitsma (1928-2009) uitgebreid onderzoek verricht naar de veelzijdige Friese

De wereld in 18 lessen: Christopher Williams

NARCIS (Netherlands)

Berrebi, S.

2011-01-01

Hij is een echte artist’s artist, de conceptuele fotograaf Christopher Williams. Sinds hij in Duitsland woont en werkt, vindt zijn afgewogen werk, dat de fotografie tegelijk eert en ondervraagt, steeds makkelijker onderdak in Europese kunstinstituten, zoals dit voorjaar bij Museum Dhondt-Dhaenens in

Burnout : de stand van zaken

NARCIS (Netherlands)

Taris, T.; Houtman, I.L.D.; Schaufeli, W.

2013-01-01

Dit artikel geeft een overzicht van de stand van zaken in het onderzoek naar burnout. Burnout is een syndroom van extreme vermoeidheid (uitputting), afstand nemen van het werk (distantie) en weinig vertrouwen in het eigen kunnen (verminderde competentie), waarbij de oorzaken voor deze aspecten

Verkennende bacteriologische zwemwaterbeoordeling volgens EU richtlijn 2006/7/EG

NARCIS (Netherlands)

Slijkerman, D.M.E.; Heusinkveld, J.H.T.

2007-01-01

Op 24 maart 2006 trad de nieuwe zwemwaterrichtlijn (76/160/EEG) in werking. Deze richt zich op de bescherming van de gezondheid van de zwemmer. De richtlijn toetst op bacteriologische parameters (totaal coliformen en fecale coliformen) ter voorkoming van maag- en darmklachten, maar ook meer

Verandering in ervaren stress en herstel bij teamsporters: gezond vs. geblesseerd

NARCIS (Netherlands)

M.S. Brink; Koen A.P.M. Lemmink; H.T.D. van der Does

2014-01-01

Teamsporters hebben een hoog blessure risico. Verondersteld wordt dat psychosociale stress en herstel bijdragen aan het blessurerisico. Zo zal een sporter die veel stress heeft van werk of studie dezelfde fysieke belasting zwaarder ervaren. Het is daarom belangrijk om inzicht te krijgen in de

Banken horen niet thuis op de beurs

NARCIS (Netherlands)

Romme, A.G.L.

2012-01-01

De zelfregulerende werking van banken is een illusie gebleken. Keer op keer blijken bankiers niet in staat zijn om zelf de gewenste structuurverbeteringen in gang te zetten. De Eindhovense econoom Romme pleit daarom voor een fundamentele transformatie van de bancaire wereld, vanuit het basisidee dat

Een moslim als gemeentelijk bruggenbouwer? Het ontslag van Tariq Ramadan

NARCIS (Netherlands)

Wiegers, G.; van Zessen, N.

2009-01-01

Het ontslag van Tariq Ramadan heeft veel ophef veroorzaakt. De doorslag gaf zijn werk voor Press TV. Gerard Wiegers en Nelleke van Zessen stellen, net zoals Ramadan zelf, dat de controverse rond zijn opvattingen over homoseksualiteit het kernprobleem vormde. Ramadan bleek niet de vrijzinnige moslim

25 jaar (uitsluiting van het) Weens Koopverdrag in Nederland

NARCIS (Netherlands)

Kruisinga, S.A.

Op 1 januari 2017 was het precies 25 jaar geleden dat het Weens Koopverdrag (CISG) in Nederland in werking trad. Partijen bij een internationale koopovereenkomst kunnen de toepassing van dit verdrag geheel of gedeeltelijk uitsluiten (art. 6 CISG). Van deze mogelijkheid wordt in de praktijk

"This one is stronger" : Spotlights on the lifelong learning professional-in-action

NARCIS (Netherlands)

van der Linden, Josje

2016-01-01

Om te kunnen omgaan met de veranderende realiteit in leven en werk, wordt wereldwijd een leven lang leren aangemoedigd. Het vierde duurzame ontwikkelingsdoel, vastgesteld in september 2015, weerspiegelt dit: “het verzekeren van kwalitatief goed onderwijs en het bevorderen van de mogelijkheden om een

Incoterms in de internationale handelspraktijk

NARCIS (Netherlands)

Sonja van Hall

2011-01-01

Op 1 januari 2011 zijn de nieuwe Incoterms 2010 in werking getreden. De benaming Incoterms is een acroniem voor International Commercial Terms, een set handelstermen die wordt beschreven en uitgegeven door de Internationale Kamer van Koophandel te Parijs. Het opstellen van een nieuwe set Incoterms

El empresario agricola en el jugoso negocio de las frutas y hortalizas de Mexico

NARCIS (Netherlands)

Gonzalez Chavez, H.

1994-01-01

Dit werk heeft als doel om het veranderingsproces uit te leggen dat een landbouwstreek heeft ondergaan door de komst van een van oorsprong Noordamerikaanse exportondernemingen van landbouwprodukten. Deze ondernemingen zijn op grote schaal met de verbouw begonnen van groenten en fruit voor de

(Siegfried), Helena Gunter

African Journals Online (AJOL)

Siegfried),. Helena Gunter (Op 'n plaas in Afrika) en verder terug in die tyd: Spoor (Sonja Loots), Kom slag. 'n bees (Izak de Vries) asook werke van Jaco. Botha, Tom Dreyer en andere. In die onlangse verlede was daar ook Maal van Nicole Jaekel ...

Florence voorbij? : over verplegen, passie & wetenschappelijk onderzoek

NARCIS (Netherlands)

Schuurmans, M.J.

2010-01-01

Honderd jaar geleden overleed Florence Nightingale, zonder twijfel de bekendste verpleegkundige ooit. Nightingale wordt vaak geassocieerd met haar roeping voor de zorg. Haar werk in de Krimoorlog leverde haar de bijnaam ‘the lady with the lamp’ op. In verpleegkundige kringen wordt Nightingale tot op

Reductie van complexiteit binnen IFRS: wie is aan zet?

NARCIS (Netherlands)

Brouwer, A.; Tahtah, J.

2012-01-01

IFRS heeft bijgedragen aan de transparantie van financiële verslaggeving en efficiënte werking van kapitaalmarkten. IFRS wordt echter ook regelmatig bekritiseerd vanwege haar complexiteit. Deze complexiteit ondermijnt de begrijpelijkheid van financiële verslaggeving. In dit artikel gaan we in op een

Functions with non-isolated singularities on singular spaces

NARCIS (Netherlands)

Jiang, Guangfeng

1998-01-01

Dit proefschrift is een studie van functies op complexe singuliere ruimten met waarden in C . In het bijzonder behandelt het functies met niet-ge?soleerde singulariteiten. Het bouwt enerzijds voort op het werk van Dimca, Bruce- Roberts, Wall en Tibar over functies met ge?soleerde singulariteiten

Campagne begonnen: Samen sterk voor preventie

NARCIS (Netherlands)

Crone, A.

2012-01-01

De Europese campagne 'Samen sterk voor preventie', een initiatief van het Europees Agentschap voor veiligheid en gezondheid op het werk (EU-OSHA) in Bilbao, wordt in Nederland gecoördineerd door TNO/NL - Focal Point. Werkgevers- en werknemersorganisaties en de overheid werken hierin samen aan het

Nachruf für Hartmut Schulz : (13. Juli 1939 - 19. Juni 2003)

OpenAIRE

Klee, Rainer; Buttler, Karl Peter; Hodvina, Sylvain

2003-01-01

Am 19. Juni 2003 verstarb Hartmut Schulz, einer der Gründer der BVNH. Leben und Werk werden in einem durch Rainer Klee verfassten Nachruf gewürdigt. Es folgt eine von Karl Peter Buttler und Sylvain Hodvina erstellte Liste der Veröffentlichungen von Hartmut Schulz.

Vertrouwenswerk in de groei : de praktijk van de politie

NARCIS (Netherlands)

Nuyens, M.; Vries, S. de; Bossche, S.N.J. van den

2002-01-01

Het tegengaan van ongewenste omgangsvormen op het werk is al jaren een aandachtspunt binnen de Nederlandse politie. Het aanstellen van vertrouwenspersonen is één van de instrumenten die worden ingezet om ongewenste omgangsvormen tegen te gaan. Het NISSO stelde, op basis van een door hen uitgevoerd

Superplasticiteit bij Cern

NARCIS (Netherlands)

Snippe, Q.H.C.; Snippe, Corijn

2008-01-01

Op CERN, het Europees onderzoekscentrum voor subatomaire fysica in Genève, wordt dit jaar een nieuwe deeltjesversneller, de Large Hadron Collider (LHC), in werking gesteld die nieuwe inzichten moet bieden over hoe de kleinste deeltjes der materie zich gedragen. Om hierachter te komen, is op plaatsen

Consumentenonderzoek in het Restaurant van de Toekomst

NARCIS (Netherlands)

Wijk, de R.A.; Gorselink, M.; Steenbekkers, L.P.A.; Wabeke, M.; Thomasson, T.

2010-01-01

Miljoenen mensen lunchen dagelijks op hun werk. Over bijvoorbeeld motieven bij de keuze van maaltijdcomponenten, de invloed van de inrichting van het restaurant of variaties in het assortiment op dit keuzegedrag is weinig tot niets bekend. In het Restaurant van de Toekomst doet de Consumer Science

De beteekenis van het antivirus van Besredka in de heelkunde. Een klinisch-experimenteele studie

NARCIS (Netherlands)

Klein, Samuel Alexander

1934-01-01

Overzien wij de literatuur, welke naar aanleiding van Besredka's antivirus-theorie is ontstaan, dan treffen wij onder de zeer vele uiteenloopende meeningen en opvattingen één feit aan, waaromtrent het meerendeel van de onderzoekers eenzelfde zienswijze is toegedaan en wel dit feit, dat de werking

Mothers, work and childcare

NARCIS (Netherlands)

Ingrid Ooms; Evelien Eggink; Edwin van Gameren

2007-01-01

Original title: Moeders, werk en kinderopvang in model. The government wants women to go out to work more. The choices made by women between working and looking after children are accordingly receiving a great deal of attention. This report describes which factors influence these choices by

Inzicht in beslisgedrag maakt dat meer burgers meedoen

NARCIS (Netherlands)

Kerstholt, J.H.

2014-01-01

Participatiesamenleving Inzicht in beslisgedrag maakt dat meer burgers meedoen Waar was de bank van de dode buurvrouw? De sekte van de burgerkracht Al het werk is zingevend, ook het vrijwillige De ondernemende burger rukt op, schort het oordeel even op Blij met het luide debat over de

Het hoge woord : Beschouwingen en boutades

NARCIS (Netherlands)

Willemsen, August

2006-01-01

'Het is bij mij begonnen met nieuwsgierigheid', zo verwoordt August Willemsen (1936) zijn levenslange toewijding aan het vertalen, in het bijzonder van Portugese en Braziliaanse literatuur. In Het hoge woord schrijft hij virtuoos over leven en werk van de door hem in Nederland geïntroduceerde

Pyridine alcohols and thiols : Synthesis, properties and applications

NARCIS (Netherlands)

Koning, Bartjan

2000-01-01

Enzymen spelen in het leven van mens, dier en plant een enorm grote rol. Enzymen zijn biologische katalysatoren dwz. versnellers van (bio)chemische processen die zich in levende organismen afspelen. Enzymen zijn eiwitten die opgebouwd zijn uit aminozuren. Om meer inzicht te krijgen in de werking van

Het aanvullen van een leemte in de overeenkomst naar Nederlands en Engels recht

NARCIS (Netherlands)

Hendrikx, A.M.M.; Boom, van W.H.; Breedveld-de, Voogd C.G.; Castermans, A.G.; De, Deugd-Dijkman M.D.R.M.; Hijma, J.

2016-01-01

In deze bijdrage wordt stilgestaan bij de rol van de redelijkheid en billijkheid bij de aanvulling van een leemte in een overeenkomst naar Nederlands recht en de aanvullende werking van implied terms in het Engelse recht, waarbij ook gekeken zal worden naar de verschillen tussen beide

Trends in recent South African linguistic research | van Rooy ...

African Journals Online (AJOL)

Die primêre teoretiese vertrekpunte is die generatiewe paradigma vir werk oor die sintaksis van die Afrikatatale, kognitiewe linguistiek vir studies oor die sematiek in Afrikaans en die Semitiese tale en tipologiese funksionele benaderings en korpuslinguistiek. Nadat die tendense vasgestel is, word aandag gegee aan ...

Waardoor geraakt de Vlaamse werknemer gestresseerd?

NARCIS (Netherlands)

Van Ruysseveldt, Joris

2010-01-01

Op basis van het Job Demands-Resources (JD-R) model wordt gezocht naar een verklaring voor verschillen in niveaus van psychische vermoeidheid en plezier in het werk bij een representatieve steekproef uit de Vlaamse beroepsbevolking (N = 12.095). Het JD-R model veronderstelt dat de aanwezigheid van

Change Management

NARCIS (Netherlands)

Bouwhuijsen, van den W.J.M.J.

2008-01-01

In dit artikel verstaan we onder "CHANGE MANAGEMENT" het managen van wijzigingen en toevoegingen van het te realiseren object gedurende het gehele bouwproces tot de oplevering van het werk, zoals ik deze vanuit mijn ervaringen beleef. Het onderhoud en beheer laten we buiten beschouwing, omdat deze

Working within limits

NARCIS (Netherlands)

Gerda Jehoel-Gijsbers

2010-01-01

Original title: Beperkt aan het werk. For many years, the Netherlands was known as a country with high levels of sickness absenteeism and a large number of incapacity benefit claimants. At European level, this was sometimes referred to as 'the Dutch disease'. Many policy measures later,

Brengt sport mensen in beweging?

NARCIS (Netherlands)

Cremer, R.

2011-01-01

De titel is natuurlijk niet letterlijk bedoeld. De onderliggende vraag is: gaat het in beweging komen dóór sport samen met het in beweging komen voor werk? Uiteenlopende effecten van beweging kunnen in dit verband worden aangehaald, zoals veranderingen in de energiehuishouding, fysieke behendigheid,

Hans Küng: "Projekt Weltethos "

OpenAIRE

Altmanninger, Maria

2002-01-01

Bei dieser Arbeit werde ich mich vor Allem auf zwei Werke beziehen: Küng,Hans:Projekt Weltethos.Piper.München 1990. Küng,Hans;Kuschel,Karl-Josef (Hg.):Weltfrieden durch Religionsfrieden.Die unter Punkt Acht aufgeführte Stellungnahme wurde ausschließlich von mir verfasst.

Deelname aan de samenleving van mensen met een beperking: participatiemonitor 2007.

NARCIS (Netherlands)

Hoogen, P. van den; Cardol, M.; Speet, M.; Spreeuwenberg, P.; Rijken, M.

2008-01-01

Hoe doen mensen met een beperking mee in de maatschappij? Mensen met een lichamelijke beperking wonen en werken meestal net als iedereen, en ook zij zijn niet altijd tevreden met hun werk. Mensen met een verstandelijke beperking wonen en werken vaak in een speciale omgeving. Het overheidsbeleid

Van Homo Ludens naar Homo Turisticus: regressie of stap in de menselijke evolutie?

NARCIS (Netherlands)

Lengkeek, J.

2009-01-01

In zijn afscheidsrede wilde hoogleraar Jaap Lengkeek (Wageningen Universiteit) terugblikken op een idee, een begrip, dat op zijn eigen werk de afgelopen jaren invloed heeft gehad. Het begrip dat hij hiervoor koos is 'Homo Ludens', de spelende mens, dat door de bekende historicus Johan Huizinga in

Werkboek agressie en pesten op het werk

NARCIS (Netherlands)

Evers, G.; Hubert, A.; Kroft, F. van der; Nuyens, M.; Willemsen, M.; Sluijs, R. van der; Davits, R.; Rijcken, V.

2003-01-01

Sommige gemeentelijke ambtenaren komen in aanraking met agressief gedrag van klanten. De redenen voor dit agressieve gedrag zijn uiteenlopend. Zo wil de ene klant zijn frustratie uiten en wil de ander iets gedaan krijgen van de betrokken werknemer. Zulk gedrag is onacceptabel en gemeentebestuurders

Metageschiedenis in het werk van Peter Blum

African Journals Online (AJOL)

vluchtte de familie voor Hitler, want er zijn aanwijzigingen dat Blum of in elk geval zijn moeder joods was (haar meisjesnaam was Levi). Om vast te stellen of Blum inderdaad joods was, heeft Blums biograaf Kannemeyer zelfs discreet bij een niet nader genoemde getuige geïnformeerd of hij besneden was, hetgeen niet het ...

Sexualität im Werk Arno Schmidts

OpenAIRE

Reischert, Jessica

2006-01-01

Die Sexualität im Frühwerk Arno Schmidts stellt ein umfangreiches und komplexes Thema dar, das dennoch auf gewisse Grundmuster und –vorgänge reduziert werden kann. So haben sich bei der Begegnung von Menschen untereinander klare Linien ergeben, anhand derer viele Gespräche eingeordnet und analysiert werden können. Unterschieden werden können mehrere Gesprächstypen, in denen sich bestimmte Verhaltensweisen der Schmidtschen Protagonisten zeigen: In den geschlechtlich gemischten Gesprächsrunden ...

Bohuslav Martinů – Werk und Wirkung [...

Czech Academy of Sciences Publication Activity Database

Gabrielová, Jarmila

2009-01-01

Roč. 46, č. 4 (2009), s. 429-431 ISSN 0018-7003 Institutional research plan: CEZ:AV0Z90580513 Keywords : Bohuslav Martinů (1890–1959) * selected music ological events 2009 Subject RIV: AL - Art, Architecture, Cultural Heritage

Verkeersonveiligheid bij werk in uitvoering : een literatuurstudie.

NARCIS (Netherlands)

Gent, A.L. van

2007-01-01

This report deals with the results of the first phase of the Road Safety at Roadworks study that CROW has commissioned SWOV to carry out. It consists of a literature study and a review of useful sources for crash data and data of road works. The main goals are (1) increasing insight into the number,

Het juiste werk voor een bijzonder talent?

NARCIS (Netherlands)

Wijn, R.; Kleij, R. van der

2012-01-01

TNO draagt met diverse onderzoeken bij aan het ontwikkelen en toepassen van kennis om de effectiviteit van cameratoezicht te vergroten. Dit artikel beschrijft een onderzoek naar de mogelijkheid om mensen met stoornissen in het autistische spectrum in te zetten in cameratoezichtcentrales.

Preexisting semantic representation improves working memory performance in the visuospatial domain.

Science.gov (United States)

Rudner, Mary; Orfanidou, Eleni; Cardin, Velia; Capek, Cheryl M; Woll, Bencie; Rönnberg, Jerker

2016-05-01

Working memory (WM) for spoken language improves when the to-be-remembered items correspond to preexisting representations in long-term memory. We investigated whether this effect generalizes to the visuospatial domain by administering a visual n-back WM task to deaf signers and hearing signers, as well as to hearing nonsigners. Four different kinds of stimuli were presented: British Sign Language (BSL; familiar to the signers), Swedish Sign Language (SSL; unfamiliar), nonsigns, and nonlinguistic manual actions. The hearing signers performed better with BSL than with SSL, demonstrating a facilitatory effect of preexisting semantic representation. The deaf signers also performed better with BSL than with SSL, but only when WM load was high. No effect of preexisting phonological representation was detected. The deaf signers performed better than the hearing nonsigners with all sign-based materials, but this effect did not generalize to nonlinguistic manual actions. We argue that deaf signers, who are highly reliant on visual information for communication, develop expertise in processing sign-based items, even when those items do not have preexisting semantic or phonological representations. Preexisting semantic representation, however, enhances the quality of the gesture-based representations temporarily maintained in WM by this group, thereby releasing WM resources to deal with increased load. Hearing signers, on the other hand, may make strategic use of their speech-based representations for mnemonic purposes. The overall pattern of results is in line with flexible-resource models of WM.

Dementia and the Deaf community: knowledge and service access.

Science.gov (United States)

Ferguson-Coleman, Emma; Keady, John; Young, Alys

2014-01-01

This study concerns culturally Deaf people in the United Kingdom who use British Sign Language (BSL). Its objective was to explore how Deaf people's knowledge about dementia and access to services is mediated by their minoritised cultural-linguistic status. Twenty-six members of the Deaf community participated in one of three Deaf-led focus groups in BSL corresponding with the sample of: Deaf people over the age of 60 without dementia; Deaf people aged 18-60 working professional roles unconnected with dementia services; ordinary members of the Deaf community aged 18-60. Data were subjected to a thematic content analysis. Participants' concerns about their poor levels of knowledge and understanding of dementia were augmented by their awareness that without sustained social contact in BSL opportunities for earlier recognition of dementia would be lost. Although primary care services were identified as the first port of call for dementia-related concerns, there was widespread mistrust of their effectiveness because of failures in communication and cultural competence. Confirmed diagnosis of dementia was not viewed as a gateway to services and support because Deaf organisations, dementia-related organisations and mainstream adult services were perceived to be ill-equipped to respond to the needs of Deaf people with dementia. Locating problems of late diagnosis within the Deaf community's poor awareness and knowledge of dementia fails to recognise the structural barriers Deaf people face in timely access to services and accurate recognition of dementia-related changes.

The impact of regulations, safety considerations and physical limitations on research progress at maximum biocontainment.

Science.gov (United States)

Shurtleff, Amy C; Garza, Nicole; Lackemeyer, Matthew; Carrion, Ricardo; Griffiths, Anthony; Patterson, Jean; Edwin, Samuel S; Bavari, Sina

2012-12-01

We describe herein, limitations on research at biosafety level 4 (BSL-4) containment laboratories, with regard to biosecurity regulations, safety considerations, research space limitations, and physical constraints in executing experimental procedures. These limitations can severely impact the number of collaborations and size of research projects investigating microbial pathogens of biodefense concern. Acquisition, use, storage, and transfer of biological select agents and toxins (BSAT) are highly regulated due to their potential to pose a severe threat to public health and safety. All federal, state, city, and local regulations must be followed to obtain and maintain registration for the institution to conduct research involving BSAT. These include initial screening and continuous monitoring of personnel, controlled access to containment laboratories, accurate and current BSAT inventory records. Safety considerations are paramount in BSL-4 containment laboratories while considering the types of research tools, workflow and time required for conducting both in vivo and in vitro experiments in limited space. Required use of a positive-pressure encapsulating suit imposes tremendous physical limitations on the researcher. Successful mitigation of these constraints requires additional time, effort, good communication, and creative solutions. Test and evaluation of novel vaccines and therapeutics conducted under good laboratory practice (GLP) conditions for FDA approval are prioritized and frequently share the same physical space with important ongoing basic research studies. The possibilities and limitations of biomedical research involving microbial pathogens of biodefense concern in BSL-4 containment laboratories are explored in this review.

The Impact of Regulations, Safety Considerations and Physical Limitations on Research Progress at Maximum Biocontainment

Directory of Open Access Journals (Sweden)

Jean Patterson

2012-12-01

Full Text Available We describe herein, limitations on research at biosafety level 4 (BSL-4 containment laboratories, with regard to biosecurity regulations, safety considerations, research space limitations, and physical constraints in executing experimental procedures. These limitations can severely impact the number of collaborations and size of research projects investigating microbial pathogens of biodefense concern. Acquisition, use, storage, and transfer of biological select agents and toxins (BSAT are highly regulated due to their potential to pose a severe threat to public health and safety. All federal, state, city, and local regulations must be followed to obtain and maintain registration for the institution to conduct research involving BSAT. These include initial screening and continuous monitoring of personnel, controlled access to containment laboratories, accurate and current BSAT inventory records. Safety considerations are paramount in BSL-4 containment laboratories while considering the types of research tools, workflow and time required for conducting both in vivo and in vitro experiments in limited space. Required use of a positive-pressure encapsulating suit imposes tremendous physical limitations on the researcher. Successful mitigation of these constraints requires additional time, effort, good communication, and creative solutions. Test and evaluation of novel vaccines and therapeutics conducted under good laboratory practice (GLP conditions for FDA approval are prioritized and frequently share the same physical space with important ongoing basic research studies. The possibilities and limitations of biomedical research involving microbial pathogens of biodefense concern in BSL-4 containment laboratories are explored in this review.

The Impact of Regulations, Safety Considerations and Physical Limitations on Research Progress at Maximum Biocontainment

Science.gov (United States)

Shurtleff, Amy C.; Garza, Nicole; Lackemeyer, Matthew; Carrion, Ricardo; Griffiths, Anthony; Patterson, Jean; Edwin, Samuel S.; Bavari, Sina

2012-01-01

We describe herein, limitations on research at biosafety level 4 (BSL-4) containment laboratories, with regard to biosecurity regulations, safety considerations, research space limitations, and physical constraints in executing experimental procedures. These limitations can severely impact the number of collaborations and size of research projects investigating microbial pathogens of biodefense concern. Acquisition, use, storage, and transfer of biological select agents and toxins (BSAT) are highly regulated due to their potential to pose a severe threat to public health and safety. All federal, state, city, and local regulations must be followed to obtain and maintain registration for the institution to conduct research involving BSAT. These include initial screening and continuous monitoring of personnel, controlled access to containment laboratories, accurate and current BSAT inventory records. Safety considerations are paramount in BSL-4 containment laboratories while considering the types of research tools, workflow and time required for conducting both in vivo and in vitro experiments in limited space. Required use of a positive-pressure encapsulating suit imposes tremendous physical limitations on the researcher. Successful mitigation of these constraints requires additional time, effort, good communication, and creative solutions. Test and evaluation of novel vaccines and therapeutics conducted under good laboratory practice (GLP) conditions for FDA approval are prioritized and frequently share the same physical space with important ongoing basic research studies. The possibilities and limitations of biomedical research involving microbial pathogens of biodefense concern in BSL-4 containment laboratories are explored in this review. PMID:23342380

Neuroblabla

NARCIS (Netherlands)

Delleman, Otto

2012-01-01

De laatste decennia groeit de kennis over de werking van de hersenen explosief. Frank (2010) haalt met instemming de bekende neuroloog Ramachandran aan, die beweert dat we op de drempel van een vijfde revolutie staan. De eerste werd teweeggebracht door Copernicus met zijn claim dat de aarde niet het

Beloken blikvelden in de Lage Landen: Eenentwintigste-eeuwse ...

African Journals Online (AJOL)

De verkennende studies willen vooral van “historisch-documentaire” aard zijn en een beeld construeren waaruit blijkt hoe het vertaalde literaire werk door de. Nederlandse (en Vlaamse) kritiek is gerecipieerd. In hoeverre deze recent (her)- uitgegeven Afrikaanse poëzie ook effectief verweven is geraakt in het Nederlandse.

Het effect van het bijvoeren van tarwe aan vleeskuikens op de slachtrendementen

NARCIS (Netherlands)

Middelkoop, van J.H.; Harn, van J.

1994-01-01

Tarwe bijvoeren aan vleeskuikens staat momenteel volop in de belangstelling. Redenen hiervoor zijn de lage prijs van de tarwe en het positieve effect dat tarwe kan hebben op de resultaten en gezondheid van de koppel. Door het bijvoeren van tarwe wordt de werking van de spiermaag en de ontwikkeling

Het nieuwe Jeruzalem komt uit de hemel : christelijke religie en seculiere utopie

NARCIS (Netherlands)

Verkerk, M.J.

2008-01-01

Nu de ChristenUnie meeregeert zien sommige christenen nieuwe kansen om orde op zaken te stellen op ethisch gebied. Maarten Verkerk wijst aan de hand van het werk van Francis Bacon en van de regering Bush op het grote gevaar om hoge doelen te stellen aan een machtspositie.

Fysieke belasting op acht melkveehouderijbedrijven : netwerkproject Noordoost Groningen

NARCIS (Netherlands)

Roelofs, P.F.M.M.; Kroeze, G.H.; Brandsma, J.H.

2005-01-01

On eight dairy farms, labour demand and labour efficiency were studied. In 2004, labour demand during a year was calculated using the computer model AgroWerk. To obtain detailed input data for this model the farmers recorded labour times, and all farms were visited to collect input data concerning

P. S. D DIE TEOLOGIESE HOOFGEDAGTES IN KIERKEGAARD SE ...

African Journals Online (AJOL)

Test

D.Phil. DIE TEOLOGIESE HOOFGEDAGTES IN KIERKEGAARD SE. STRYD TEEN DIE HEGELSE SISTEEM. A. INLEIDENDE OPMERKING. Ons is van oordeel dat dit ongetwyfeld paslik is om in ons waardering van die persoon en werk van prof. H. P. Wolmarans, oor die Deense denker en digter, Kierkegaard, te skrywe.

Door de ogen van de ander kijken: kunst als veranderkracht

NARCIS (Netherlands)

Smilde, Rineke

2015-01-01

Presentie gehouden bij een besloten expert meeting van de KNAW en de Boekmanstichting in Amsterdam. Door de ogen van de ander kijken: kunst als veranderkracht. Ik maak graag van de gelegenheid gebruik om iets te vertellen vanuit mijn werk als lector aan het PCC van de Hanzehogeschool Groningen.

Verbeelding en principes: Enkele implicaties van Dewey’s moraalfilosofie voor een vernieuwing van de hedendaagse ethiek

NARCIS (Netherlands)

Coeckelbergh, Mark

2007-01-01

In deze presentatie onderzoek ik hoe Dewey’s moraalfilosofie kan bijdragen aan een vernieuwing van de hedendaagse ethiek door te kijken naar de rol die Dewey ziet voor verbeelding en principes in moreel redeneren. Ik toon dat zijn werk kan gebruikt worden om te argumenteren voor een omwenteling in

The seed hunter in het spoor van Vavilov (interview met C. Kik)

NARCIS (Netherlands)

Zanderink, R.; Kik, C.

2013-01-01

Er moet voor een veredelaar een grote variatie aan plantmateriaal aanwezig zijn om uit te kunnen putten zodat onze gewassen, die vaak bestaan uit monoculturen, voor de toekomst veiliggesteld worden. Het vinden van die variatie is het werk van seed hunters of zadenverzamelaars. Eén van die seed

Mislukking en succes bij de ambulante behandeling van dwangneurose

NARCIS (Netherlands)

C.A.L. Hoogduin (Cornelis Antonius Leo)

1985-01-01

textabstractMet het werk van Meyer, Rachman, Foa en Emmelkamp is een belangrijke ontwikkeling op gang gekomen met betrekking tot de behandeling van parienten met een dwangneurose. Maakte het in het verleden niet zoveel uit op welke manier deze parienten behandeld werden, de laatste jaren is het vast

GEBED IN DIE LITURGIE: 'N PRAKTIES-TEOLOGIESE VERKENNING

African Journals Online (AJOL)

die erediens voorkom nie en anders is as vrye gebede wat gelowiges bid, byvoorbeeld tydens persoonlike stiltetyd of 'n sogenaamde “skietgebed” op enige gegewe moment. Oor die laasgenoemde soort liturgiese gebed bestaan baie bronne, byvoorbeeld die bekende werk van Taft (1993)1 in die Rooms-Katolieke tradisie ...

03 Wessels 03.pmd

African Journals Online (AJOL)

Tienie01

12 Jun 2006 ... benadering definieer. Maria Edgeworth (1767-1849) het byvoorbeeld na 'n realistiese uitbeelding van haar samelewing gestreef en word as 'n belangrike invloed op beide Sir Walter Scott se historiese werke en Jane Austen se sosiale romans beskou. (Albei skrywers het haar bewonder en. 03 Wessels 03.

Kein Handbuchwissen

Directory of Open Access Journals (Sweden)

Thomas Wetzstein

2006-01-01

Full Text Available Rezensiertes Werk: Otfried Krafft, Papsturkunde und Heiligsprechung. Die päpstlichen Kanonisationen vom Mittelalter bis zur Reformation. Ein Handbuch (Archiv für Diplomatik, Schriftgeschichte, Siegel- und Wappenkunde, Beiheft 9, Köln, Weimar, Wien: Böhlau 2005, XII, 1247 S., ISBN 3-412-25805-9

03 Rutgers

African Journals Online (AJOL)

Tom

Pa saka kara: (tomo I) historia di literatura Papiamentu. Willemstad: Fundashon Pierre. Lauffer. Claassen, Anton. 1992. De navelstreng van mijn taal; Poesia bibo di Aruba. Haarlem: In de Knipscheer. Debrot, Cola. 1985-1989. Verzameld werk. (zeven delen) Amsterdam: Meulenhoff. ———. 1985a. Naschrift op Dr. David ...

Working with impairments

NARCIS (Netherlands)

Maroesjka Versantvoort; Patricia van Echtelt

2012-01-01

Original title: Belemmerd aan het werk The Netherlands was long known as a country with high sickness absenteeism rates and a burgeoning group of people who were unfit for work. In response to this, many policy measures have been introduced in recent decades which attempt to limit the benefit

Over het belang van Temminck's „Discours préliminaire" voor de zoologische Nomenclatuur

NARCIS (Netherlands)

Mees, G.F.

1957-01-01

Het gewoonlijk als „Discours préliminaire" aangeduide artikel van Temminck heeft nimmer die aandacht van dierkundigen getrokken, die het, wegens zijn systematisch belang, verdient. Ten dele vindt dit stellig zijn oorzaak in de betrekkelijke zeldzaamheid van het werk, ten dele ook in het feit dat het

Hoe kbesp re kill J,tsl Boo kR e~~ie"~s

African Journals Online (AJOL)

en verbly- dend - dat daar nog uitgewers is wat bereid is om goeie boeke te bemark, ongeag die geringe aantallesers van histories-wetenskaplike werke. Kapt A. E. van daarsveldt. MEREDITH, Martin: The past is another country, Rhodesia. 1890-1979 London, Deutsch, 1979. Hierdie boek voorsien in 'n leemte betreffende.

11 TSjoen WEB 02.pmd

African Journals Online (AJOL)

Owner

de tekst. Als Nabokov of Beckett een eerder losgelaten (dat wil zeggen een publiek gemaakte) tekst bewerken voor een volgende uitgave, dan vindt de belangstellende op basis van drukvergelijkend tekstonderzoek indicaties van een bijgestelde visie op het literaire werk zelf. Bekend in het Nederlandse taalgebied en veel ...

14 Van Krevelen 02.pmd

African Journals Online (AJOL)

Owner

23 juni 2009 ... teiten en experimenten benadrukt, maar de publieke en kritische perceptie van zijn werk lijkt de fundamentele samenhang daarvan te miskennen, en reduceert het tot gefragmenteerde, op zichzelf staande aspecten. Poëzie is levenskunst. Als Breyten Breytenbach alleen maar poëzie had geschreven was ...

Early Site Permit Demonstration Program: Siting Guide, Site selection and evaluation criteria for an early site permit application

International Nuclear Information System (INIS)

1993-01-01

In August 1991, the Joint Contractors came to agreement with Sandia National Laboratories (SNL) and the Department of Energy (DOE) on a workscope for the cost-shared Early Site Permit Demonstration Program. One task within the scope was the development of a guide for site selection criteria and procedures. A generic Siting Guide his been prepared that is a roadmap and tool for applicants to use developing detailed siting plans for their specific region of the country. The guide presents three fundamental principles that, if used, ensure a high degree of success for an ESP applicant. First, the site selection process should take into consideration environmentally diverse site locations within a given region of interest. Second, the process should contain appropriate opportunities for input from the public. Third, the process should be applied so that it is clearly reasonable to an impartial observer, based on appropriately selected criteria, including criteria which demonstrate that the site can host an advanced light water reactor (ALWR). The Siting Guide provides for a systematic, comprehensive site selection process in which three basic types of criteria (exclusionary, avoidance, and suitability) are presented via a four-step procedure. It provides a check list of the criteria for each one of these steps. Criteria are applied qualitatively, as well as presented numerically, within the guide. The applicant should use the generic guide as an exhaustive checklist, customizing the guide to his individual situation

Site Closure Strategy Model for Creosote Site

International Nuclear Information System (INIS)

Coll, F.R.; Gray, D.R.

2009-01-01

In conjunction with RCRA site corrective action at an active wood preserving facility, a risk-based site closure strategy was developed and incorporated the performance of a dense non-aqueous phase liquid (DNAPL) source recovery remedy, a monitored natural attenuation (MNA) remedy for dissolved phase groundwater, and institutional controls. Innovative creosote DNAPL source recovery has been undertaken at the Site since 1998. Pooled creosote DNAPL is present 90 feet below ground within a transmissive sand and gravel aquifer with a saturated thickness of approximately 80 feet. The creosote DNAPL source is situated on the property boundary of the site and has generated a 1/2 mile off-site dissolved phase plume, creating significant NAPL management and remedial technology verification issues. To date, over 120,000 gallons of creosote DNAPL have been recovered from the subsurface utilizing a modified circulation well technology. A mass discharge flux protocol was developed to serve as a major performance metrics for the continuation of source removal efforts and to support the application of monitored natural attenuation as an associated remedial technology for groundwater. The mass removal success has supported the MNA remedy for dissolved phase groundwater and the associated development of institutional controls. The enacted site management strategy outlines the current and future risk management activities for the Site and represents an appropriate site closure strategy for the Site. (authors)

Study of site layout in the Rokkasho site

International Nuclear Information System (INIS)

Sato, Kazuyoshi; Tamura, Kousaku; Yagenji, Akira; Sekiya, Shigeki; Takahashi, Hideo; Neyatani, Yuzuru; Uehara, Masaharu; Motohashi, Keiichi; Hashimoto, Masayoshi; Ogino, Shunji; Nagamatsu, Nobuhide

2006-03-01

The Final Design Report (FDR) of the International Thermonuclear Experimental Reactor (ITER) was published on July 2001 as a summary of the Engineering Design Activity (EDA). After the EDA, site dependent design has been investigated for the invitation of ITER toward Rokkasho Site (Iyasakadai area) in Aomori prefecture. This report describes the results of site layout of major buildings and structures of ITER in the Rokkasho-Site. The data of the ground near the site and the results of site dependent design in Japan were applied to this study. Through this study, the most appropriate site layout has been constructed with satisfaction of following conditions. (1) Bedrock level at the tokamak complex building is relatively high and it can be reduced the cost of excavation and foundation work. (2) Total amount of excavation soil for site preparation is minimized and the flexibility of the layout is ensured with flat ground level. (3) Accessibility of human and equipments, reduction of noise and vibration to the environment can be obtained. Total length of ducts and piping between buildings in site is minimized. (author)

Biosecurity and Biodefense: Lessons from Ebola Virus Outbreak

CSIR Research Space (South Africa)

Lebea, Phiyani J

2014-01-01

Full Text Available , should a contagious outbreak be suspected. Such a policy would be adopted by regional member states since diseases such as Ebola respect no national boundaries. Secondly, research infrastructure including BSL 4 laboratories that address research on animal...

SPARK-UP; Seaweed Production And Refining of Kelp, Ulva and Palmaria

NARCIS (Netherlands)

Wald, J.; Visser, de W.; Brandenburg, W.A.; Jongschaap, R.E.E.; Werf, van der A.K.; Deelman, Berth-Jan; Helmendach-Nieuwenhuize, Carola

2016-01-01

In het SPARK-UP project, waarin de partners Arkema, PRI-WUR en North Seaweed samenwerkten aan de ontwikkeling van toepassing van zeewier in de biobased economy, is de afgelopen jaren veel werk verzet. In een bassin op het terrein van Arkema, heeft PRI een teeltsysteem opgezet en in gebruik genomen,

Gewalt ohne Monopol

Directory of Open Access Journals (Sweden)

Marc Grohmann

2003-01-01

Full Text Available Rezensiertes Werk:Peter Hanser, Trutz von Trotha, Ordnungsformen der Gewalt. Reflexionen über die Grenzen von Recht und Staat an einem einsamen Ort in Papua-Neuguinea (Siegener Beiträge zur Soziologie 3, Köln: Rüdiger Köppe 2002, 448 S., ISBN 3-89645-330-0

Jullie kunnen het Weststellingwerf!

NARCIS (Netherlands)

Heijne, Leo; Pierie, Frank

2017-01-01

Weststellingwerf werkt momenteel aan haar Omgevingsvisie en doet dit samen met de inwoners. Deze visie gaat over de toekomst van de woon-, werk- en leefomgeving van de gemeente Weststellingwerf. De gemeente moedigt in dit kader de inwoners aan om mee te denken en samen te "puzzelen" voor een

GE[)URE~[)E

African Journals Online (AJOL)

liter te orienteer. n. Direktoraat. Openbare. Betrekkinge is onder beheer van die Oorlogskantoor gestig en 'n aantal offisiere is aangestel. Hulle werk was om die Leer te beskrywe en soveel as moontlik in die openbare pers te laat verskyn. Hierdie organisasie het goeie vredestydse diens gelewer, maar sou die oorlogstyd ...

To work or not to work

NARCIS (Netherlands)

Patricia van Echtelt; Stella Hoff

2008-01-01

Original title: Wel of niet aan het werk. 'More people in paid work' is the central policy objective of the Dutch government in relation to employment. In order to achieve this goal, it is necessary to know what prevents non-workers from joining the labour process, and what prevents workers

Benjamin Constant, surveillance en de strijd voor vrijheid en privacy : Vergeten gevoeligheden in een door Jeremy Bentham beïnvloed veiligheidsklimaat

NARCIS (Netherlands)

de Hert, Paul; de Hert, P.; Kinneging, A.; Colette, M.

2015-01-01

In deze bijdrage, concentreer ik me op Benjamin Constants (1767-1830) Principes de politique, een meesterwerk van de liberale theorie. In dit werk uit 1810 geeft Constant zelf op verschillende plaatsen aan dat hij geschiedenis aan het schrijven is. Hij is, zo merkt hij op, de eerste om aandacht te

IN KRITIESE BESKOUING VAN INLEIDING TOT DIE SEMANTIEK

African Journals Online (AJOL)

Dit laat twee interpretasie- moontlikhede oop: "later" kan of beteken "later in Syntactic Structures. (Chomsky 1957)", of "tussen Syntactic Structures en Katz en Fodor (1963) se The Structure of a Semantic Theory". Laasgenoemde werk is naamlik die eerste wat deur De Klerk as deel van die tweede periode, "die aanloop tot.

Deon Meyer

African Journals Online (AJOL)

Owner

of ten minste gekontekstualiseer, word. By die gastehuis, La Petite Margaux, is daar drie lyke met drie perfekte kopskote. Twee van die oorledenes is militêre tipes, oud-SAPD- lyfwagte wat as persoonlike sekuriteitswagte vir Jeanette Louw, besturende direkteur van. Body Armour (soos in Onsigbaar en 7 dae), ge- werk het.

Turgot en Smith; een paar apart

NARCIS (Netherlands)

Hoyng, A.C.

2011-01-01

Anne-Claire Hoyng deed onderzoek naar het boek The Wealth of Nations van Adam Smith (1723-1790). Ze concludeert dat Smith voor het schrijven van zijn boek een werk van de Fransman Anne-Robert Jacques Turgot (1727-1781) als inspiratiebron gebruikte (Réflexions sur la Formation et la distribution des

Competition between informal care and paid work

NARCIS (Netherlands)

Edith Josten; Alice de Boer

2015-01-01

Oringinal title: Concurrentie tussen mantelzorg en betaald werk The Dutch government would like citizens to provide more care to loved ones who need it – perhaps caring for an elderly parent or looking after a partner with a long-term illness. At the same time, the government wishes to raise

RIVM open data

NARCIS (Netherlands)

van Loenen, B.; Welle Donker, F.M.; Ploeger, H.D.

2016-01-01

Onderzoek uitgevoerd in opdracth van RIVM.
Open data is een van de pijlers van onze informatie-economie en van een transparante overheid. Ook de minister van de minister van Volksgezondheid, Welzijn en Sport (VWS) heeft in 2015 aangekondigd werk te gaan maken van open data in de zorg. Naast het

Prestatieladder Socialer Ondernemen Handleiding versie 1.0

NARCIS (Netherlands)

Bongers, P.M.

2012-01-01

De PSO is het eerste objectieve meetinstrument dat de sociale bijdragen van bedrijven in kaart brengt. Aukje Smit, projectleider PSO bij TNO: “Met een PSO-erkenning kunnen de bedrijven die er echt werk van maken zich nu onderscheiden van de concurrent. Voor gemeenten en UWV is de PSO ook interessant

Recht en vrede bij Hans Kelsen : een herwaardering van Kelsens rechtsfilosofie : juridisch pacifisme als stilzwijgende betekenis van zijn Zuivere Rechtsleer

NARCIS (Netherlands)

Notermans, Mathijs Eugène

2016-01-01

Hans Kelsen staat in de wereld van de rechtsfilosofie en –theorie bekend als één van de belangrijkste rechtsgeleerden van de 20ste eeuw en zijn belangrijkste werk dat hem die bekendheid heeft opgeleverd, de Reine Rechtslehre, is dan ook ‘wereldberoemd’. Minder bekendheid geniet hij als juridisch

Theory for site-site pair distribution functions of molecular fluids. II. Approximations for the Percus--Yevick site-site direct correlation functions

International Nuclear Information System (INIS)

Johnson, E.

1977-01-01

A theory for site-site pair distribution functions of molecular fluids is derived from the Ornstein-Zernike equation. Atom-atom pair distribution functions of this theory which were obtained by using different approximations for the Percus-Yevick site-site direct correlation functions are compared

SitesIdentify: a protein functional site prediction tool

Directory of Open Access Journals (Sweden)

Doig Andrew J

2009-11-01

Full Text Available Abstract Background The rate of protein structures being deposited in the Protein Data Bank surpasses the capacity to experimentally characterise them and therefore computational methods to analyse these structures have become increasingly important. Identifying the region of the protein most likely to be involved in function is useful in order to gain information about its potential role. There are many available approaches to predict functional site, but many are not made available via a publicly-accessible application. Results Here we present a functional site prediction tool (SitesIdentify, based on combining sequence conservation information with geometry-based cleft identification, that is freely available via a web-server. We have shown that SitesIdentify compares favourably to other functional site prediction tools in a comparison of seven methods on a non-redundant set of 237 enzymes with annotated active sites. Conclusion SitesIdentify is able to produce comparable accuracy in predicting functional sites to its closest available counterpart, but in addition achieves improved accuracy for proteins with few characterised homologues. SitesIdentify is available via a webserver at http://www.manchester.ac.uk/bioinformatics/sitesidentify/

Blueprint model and language for engineering cloud applications

NARCIS (Netherlands)

Nguyen, D.K.

2013-01-01

The research presented in this thesis is positioned within the domain of engineering CSBAs. Its contribution is twofold: (1) a uniform specification language, called the Blueprint Specification Language (BSL), for specifying cloud services across several cloud vendors and (2) a set of associated

78 FR 110 - Supplemental Record of Decision; Final Supplementary Risk Assessment for the Boston University...

Science.gov (United States)

2013-01-02

..., questions were raised specifically about the potential risks of the biosafety level 4 (BSL-4) laboratory. To... epidemiology, risk assessment, environmental justice, risk communications, biosafety, and infectious disease... functional personal protective equipment, and standard operating procedures were not taken into account in...

Ueberreste vorweltlicher Proboscidier von Java und Banka

NARCIS (Netherlands)

Martin, K.

1884-01-01

Junghuhn führte in seinem Werke über Java nur einen einzigen Wirbelthierrest, Carcharias megalodon, an (7, IV, pag. 97); es war ihm nicht gelungen bei seinem ersten Aufenthalte auf der Insel Reste von Säugethieren zu finden, so eifrig er auch darnach in den Höhlen des Tertiaergebirges suchte (7, IV,

Bleek planeet

African Journals Online (AJOL)

Owner

king”) en verskynsels soos el niño word be- trek. Aardverwoesting, natuurverskynsels en die geïmpliseerde rol van die mens as (dikwels gefaalde) behoeder van die natuur word in hierdie bundel met deurdagte en suggestie- ryke taal onder woorde gebring. In Bleek planeet werk heelwat van die ge- digte intertekstueel.

Zo moet het gegaan zijn : De noodzaak van alternatieve verklaringen en bekritiseerbare analyses bij zoekzaken binnen de opsporing

NARCIS (Netherlands)

Wisse, B.W.; Gosliga, S.P.; Bijsterbosch, G.

2011-01-01

Recente justitiële dwalingen in onder andere de zaak Ina Post, de Schiedammer parkmoord, de Puttense moordzaak en de zaak Lucia de Berk laten zien dat het werk van een opsporingsteam vatbaar is voor het fenomeen tunnelvisie: het gevaar dat te veel wordt vastgehouden aan één scenario/hypothese. Een

20 Resensies 03 Senekal WEB.pmd

African Journals Online (AJOL)

Owner

'n Nuwe wildernismaak as geheel wel 'n bydrae tot die grensliteratuur, veral omdat dit as een van die meer omvangryke werke van fiksie wat oor hierdie oorlog verskyn het, daartoe in staat is om verskillende nuanses van die oorlog op te roep. So byvoorbeeld kom die be- vraagtekening van die redes waarom die.

De opname van het conflictenrecht in het Nederlandse BW: een analyse van de gevolgen ervan voor de systematiek en de coherentie van het BW in zijn geheel

NARCIS (Netherlands)

Oderkerk, A.E.

2013-01-01

Op 1 januari 2012 is Boek 10 BW in werking getreden. Daarmee is het grootste deel van het Nederlandse conflictenrecht thans in het BW opgenomen. In deze monografie, die een bewerking vormt van de door de auteur op 16 november 2010 gehouden lezing voor de ‘Studiekring Prof.mr. J. Offerhaus’, wordt

Art. 1 Eerste Protocol EVRM

NARCIS (Netherlands)

Poelmann, E.

2014-01-01

Het recht op bezit is niet in het Europees Verdrag ter bescherming van de rechten van de mens en de fundamentele vrijheden (hierna: EVRM) neergelegd, maar in het Eerste Protocol daarbij (hierna: EP), dat in 1954 in werking is getreden. Het is van belang voor ogen te houden dat de Tweede Wereldoorlog

belangstel. AD Pont. S. van der Linde ea, Roeping en Belofte. Ons ...

African Journals Online (AJOL)

Test

Hoogs interessant is die opmerking oor die bybedoelings wat dikwels met die sending saamgegaan het sodat die sending soms tot 'n vervlakte en gesekulariseerde filantropiese besigheid ge vord het. Hoe verwoestend dit werk, het ons hier in Suid-Afrika al meer as een maal ten duurste moes ondervind. Dit doen goed om.

Die gebruik van 'n handpop as mede- terapeut en 'n vyfjarige ...

African Journals Online (AJOL)

p1243322

waarmee Billy Beer werk en elemente soos humor en herhaling word gebruik om ouderdomstoepaslik teenoor haar te reageer en op so manier haar unieke. “taal” te praat. In die res van die artikel word eerstens aandag gegee aan sake van 'n metodologiese aard, insluitende die gebruik van die sentrale metafoor van 'n.

Early Site Permit Demonstration Program: Siting Guide, Site selection and evaluation criteria for an early site permit application. Revision 1

Energy Technology Data Exchange (ETDEWEB)

1993-03-24

In August 1991, the Joint Contractors came to agreement with Sandia National Laboratories (SNL) and the Department of Energy (DOE) on a workscope for the cost-shared Early Site Permit Demonstration Program. One task within the scope was the development of a guide for site selection criteria and procedures. A generic Siting Guide his been prepared that is a roadmap and tool for applicants to use developing detailed siting plans for their specific region of the country. The guide presents three fundamental principles that, if used, ensure a high degree of success for an ESP applicant. First, the site selection process should take into consideration environmentally diverse site locations within a given region of interest. Second, the process should contain appropriate opportunities for input from the public. Third, the process should be applied so that it is clearly reasonable to an impartial observer, based on appropriately selected criteria, including criteria which demonstrate that the site can host an advanced light water reactor (ALWR). The Siting Guide provides for a systematic, comprehensive site selection process in which three basic types of criteria (exclusionary, avoidance, and suitability) are presented via a four-step procedure. It provides a check list of the criteria for each one of these steps. Criteria are applied qualitatively, as well as presented numerically, within the guide. The applicant should use the generic guide as an exhaustive checklist, customizing the guide to his individual situation.

Preliminary siting characterization Salt Disposition Facility - Site B

International Nuclear Information System (INIS)

Wyatt, D.

2000-01-01

A siting and reconnaissance geotechnical program has been completed in S-Area at the Savannah River Site in South Carolina. This program investigated the subsurface conditions for the area known as ''Salt Disposition Facility (SDF), Site B'' located northeast of H-Area and within the S-Area. Data acquired from the Site B investigation includes both field exploration and laboratory test data

Automatic web site authoring with SiteGuide

NARCIS (Netherlands)

de Boer, V.; Hollink, V.; van Someren, M.W.; Kłopotek, M.A.; Przepiórkowski, A.; Wierzchoń, S.T.; Trojanowski, K.

2009-01-01

An important step in the design process for a web site is to determine which information is to be included and how the information should be organized on the web site’s pages. In this paper we describe ’SiteGuide’, a tool that automatically produces an information architecture for a web site that a

Functional relationships between genes associated with differentiation potential of aged myogenic progenitors

Directory of Open Access Journals (Sweden)

Radhakrishnan Nagarajan

2010-09-01

Full Text Available Aging is accompanied by considerable heterogeneity with possible co-expression of differentiation pathways. The present study investigates the interplay between crucial myogenic, adipogenic and Wnt-related genes orchestrating aged myogenic progenitor differentiation (AMPD using clonal gene expression profiling in conjunction with Bayesian structure learning (BSL techniques. The expression of three myogenic regulatory factor genes (Myogenin, Myf-5, MyoD1, four genes involved in regulating adipogenic potential (C/EBPα, DDIT3, FoxC2, PPARγ, and two genes in the Wnt-signaling pathway (Lrp5, Wnt5a known to influence both differentiation programs were determined across thirty-four clones by quantitative reverse transcriptase polymerase chain reaction (qRT-PCR. Three control genes were used for normalization of the clonal expression data (18S, GAPDH and B2M. Constraint-based BSL techniques, namely (a PC Algorithm, (b Grow-shrink algorithm (GS, and (c Incremental Association Markov Blanket (IAMB were used to model the functional relationships (FRs in the form of acyclic networks from the clonal expression profiles. A novel resampling approach that obviates the need for a user-defined confidence threshold is proposed to identify statistically significant FRs at small sample sizes. Interestingly, the resulting acyclic network consisted of FRs corresponding to myogenic, adipogenic, Wnt-related genes and their interaction. A significant number of these FRs were robust to normalization across the three house-keeping genes and the choice of the BSL technique. The results presented elucidate the delicate balance between differentiation pathways (i.e. myogenic as well as adipogenic and possible cross-talk between pathways in AMPD.

Retransformation of a distance to a canonical form and a potential of a polygonal prism; Kyori no shujiku henkan to takakuchu no potential

Energy Technology Data Exchange (ETDEWEB)

Koyama, S

1996-10-01

For the potential of a polygonal prism (FLS) reported in the previous paper, the distance R was expressed by two constitutions, i.e., R{sup 2} = X{sup 2}+Y{sup 2}+Z{sup 2} (eq-1) and R{sup 2} = Z{sup 2}+(1+a{sup 2}){sup -1}(Y-aX){sup 2}+(1+a{sup 2}){sup -1}(X-aY){sup 2} (eq-2). There were two principal axes mixed, i.e., (X,Y,Z) and (X+aY,Y-aX,Z). The mixture of principal axes was initially caused by the integration with an assumption of principal axis of eq-1, by the conversion of the integrated result into the curvilinear integral assuming Y = aX+b, and then by the integration still using R{sup 2} = X{sup 2}+(aX+b){sup 2}+Z{sup 2} = (1+a{sup 2})X{sup 2}+2abX+b{sup 2}+Z{sup 2}, in the process of calculation of FSL. The defect of the mixture of principal axes was that the primitive function of the potential was not symmetric, and that the integration and the partial differential were very hard. The order of substitution of Y = aX+b was reversed, and the potential of a polygonal prism (BSL) was determined by unifying the principal axis into (X+aY,Y-aX,Z), to compare BSL with FSL. Consequently, the BSL showed one principal axis and symmetry, which resulted in the much easier calculations of integration and partial differential.

Site description of Forsmark at completion of the site investigation phase. SDM-Site Forsmark

Energy Technology Data Exchange (ETDEWEB)

2008-12-15

The Swedish Nuclear Fuel and Waste Management Co., SKB, has undertaken site characterisation in two different areas, Forsmark and Laxemar-Simpevarp, in order to identify a suitable location for a geological repository of spent nuclear fuel according to the KBS-3 method. The site investigations have been conducted in campaigns, punctuated by data freezes. After each data freeze, the site data have been analysed and modelling has been carried out with the overall purpose to develop a site descriptive model (SDM). The site descriptive model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It is also essential for safety assessment, since the model is the only source for site-specific input. Another important use of the site descriptive model is in the environmental impact assessment. An SDM is an integrated model for geology, thermal properties, rock mechanics, hydrogeology, hydrogeochemistry, bedrock transport properties and a description of the surface system. The site descriptive model compiled in the current report, SDM-Site, presents an integrated understanding of the Forsmark area at the completion of the surface-based investigations, which were conducted at Forsmark during the period 2002 to 2007. It also provides a summary of the abundant underlying data and the discipline-specific models that support the site understanding. The description relies heavily on background reports that address, in particular, details in data analyses and modelling in the different disciplines. The Forsmark area is located in northern Uppland within the municipality of Oesthammar, about 120 km north of Stockholm. The candidate area for site investigation is located along the shoreline of Oeregrundsgrepen, within the north-western part of a major tectonic lens that formed between 1.87 and 1.85 billion years ago during the Svecokarelian orogeny. The candidate area is approximately 6 km long and 2 km wide. The

Site description of Laxemar at completion of the site investigation phase. SDM-Site Laxemar

Energy Technology Data Exchange (ETDEWEB)

2009-12-15

The Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken site characterisation in two different areas, Forsmark and Laxemar-Simpevarp, in order to identify a suitable location for a geological repository of spent nuclear fuel according to the KBS-3 method. The site investigations have been conducted in campaigns, punctuated by data freezes. After each data freeze, the site data have been analysed and modelling has been carried out with the overall purpose to develop a site descriptive model (SDM). The site descriptive model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It is also essential for safety assessment, since the SDM is the only source for site-specific input. Another important use of the site descriptive model is in the environmental impact assessment. An SDM is an integrated model of geology, thermal properties, rock mechanics, hydrogeology, hydrogeochemistry, bedrock transport properties and a description of the surface system. The site descriptive model compiled in the current report, SDM-Site Laxemar, presents an integrated understanding of the Laxemar-Simpevarp area (with special emphasis on the Laxemar subarea) at the completion of the surface-based investigations, which were conducted during the period 2002 to 2007. A summary is also provided of the abundant underlying data and the discipline specific models that support the site understanding. The description relies heavily on background reports that address, in particular, details of the data analyses and modelling of the different disciplines. The Laxemar-Simpevarp area is located in the province of Smaaland within the municipality of Oskarshamn, about 230 km south of Stockholm. The candidate area for site investigation is located along the shoreline of the strait of Kalmarsund, within a 1.8 billion year old suite of well preserved bedrock belonging to the Transscandinavian Igneous Belt formed during

Site description of Laxemar at completion of the site investigation phase. SDM-Site Laxemar

International Nuclear Information System (INIS)

2009-12-01

The Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken site characterisation in two different areas, Forsmark and Laxemar-Simpevarp, in order to identify a suitable location for a geological repository of spent nuclear fuel according to the KBS-3 method. The site investigations have been conducted in campaigns, punctuated by data freezes. After each data freeze, the site data have been analysed and modelling has been carried out with the overall purpose to develop a site descriptive model (SDM). The site descriptive model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It is also essential for safety assessment, since the SDM is the only source for site-specific input. Another important use of the site descriptive model is in the environmental impact assessment. An SDM is an integrated model of geology, thermal properties, rock mechanics, hydrogeology, hydrogeochemistry, bedrock transport properties and a description of the surface system. The site descriptive model compiled in the current report, SDM-Site Laxemar, presents an integrated understanding of the Laxemar-Simpevarp area (with special emphasis on the Laxemar subarea) at the completion of the surface-based investigations, which were conducted during the period 2002 to 2007. A summary is also provided of the abundant underlying data and the discipline specific models that support the site understanding. The description relies heavily on background reports that address, in particular, details of the data analyses and modelling of the different disciplines. The Laxemar-Simpevarp area is located in the province of Smaaland within the municipality of Oskarshamn, about 230 km south of Stockholm. The candidate area for site investigation is located along the shoreline of the strait of Kalmarsund, within a 1.8 billion year old suite of well preserved bedrock belonging to the Transscandinavian Igneous Belt formed during

Site description of Forsmark at completion of the site investigation phase. SDM-Site Forsmark

International Nuclear Information System (INIS)

2008-12-01

The Swedish Nuclear Fuel and Waste Management Co., SKB, has undertaken site characterisation in two different areas, Forsmark and Laxemar-Simpevarp, in order to identify a suitable location for a geological repository of spent nuclear fuel according to the KBS-3 method. The site investigations have been conducted in campaigns, punctuated by data freezes. After each data freeze, the site data have been analysed and modelling has been carried out with the overall purpose to develop a site descriptive model (SDM). The site descriptive model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It is also essential for safety assessment, since the model is the only source for site-specific input. Another important use of the site descriptive model is in the environmental impact assessment. An SDM is an integrated model for geology, thermal properties, rock mechanics, hydrogeology, hydrogeochemistry, bedrock transport properties and a description of the surface system. The site descriptive model compiled in the current report, SDM-Site, presents an integrated understanding of the Forsmark area at the completion of the surface-based investigations, which were conducted at Forsmark during the period 2002 to 2007. It also provides a summary of the abundant underlying data and the discipline-specific models that support the site understanding. The description relies heavily on background reports that address, in particular, details in data analyses and modelling in the different disciplines. The Forsmark area is located in northern Uppland within the municipality of Oesthammar, about 120 km north of Stockholm. The candidate area for site investigation is located along the shoreline of Oeregrundsgrepen, within the north-western part of a major tectonic lens that formed between 1.87 and 1.85 billion years ago during the Svecokarelian orogeny. The candidate area is approximately 6 km long and 2 km wide. The

The relationship between work-family conflict and central life interests amongst single working mothers

Directory of Open Access Journals (Sweden)

Taryn Wallis

2003-10-01

Full Text Available This study explored the experiences of work-family conflict amongst a group of twenty single working mothers with pre-school age children. Dubin’s (1992 theory of Central Life Interests was utilised to fully understand how the differential importance of the roles played by the women informed the level and nature of the conflict experienced. A two-phase research design was employed in which questionnaire responses from the first phase formed the basis for the second phase of in-depth qualitative interviews. Results indicated that participants viewed motherhood as their Central Life Interest and that this priority could lead them to experience greater conflict between work and family demands. Although work was rated second in importance when compared to family, it was still seen as being of great significance, not only for instrumental reasons, but also for the intellectual stimulation that it provided and opportunities to exercise independence and responsibility. Opsomming Die werk-en-familie konflik-ervarings van twintig werkende enkel-moeders met voorskoolse kinders is ondersoek in hierdie projek. Dubin (1992 se teorie van sentrale lewensbelangstellings is gebruik om te bepaal hoe die belangrikheid van die twee rolle die vlak en aard van die konflik bepaal het. Die navorsing is in twee fases gedoen: ‘n vraelys in die eerste fase, opgevolg deur in-diepte kwalitatiewe onderhoude. Resultate het gewys dat die deelnemers moederskap as hul sentrale lewensbelangstelling beskou het, en dat hierdie prioriteit kon lei tot groter konflik tussen die eise van werk en familie. Alhoewel werk as ondergeskik aan familie beoordeel is, was dit nogtans van groot belang. Aan die een kant was dit vir instrumentele redes, maar dit het ook intellektuele stimulasie verskaf en geleenthede gegee om onafhanklik en verantwoordelik op te tree.

Feasibility of establishing a biosafety level 3 tuberculosis culture laboratory of acceptable quality standards in a resource-limited setting: an experience from Uganda

NARCIS (Netherlands)

Ssengooba, Willy; Gelderbloem, Sebastian J.; Mboowa, Gerald; Wajja, Anne; Namaganda, Carolyn; Musoke, Philippa; Mayanja-Kizza, Harriet; Joloba, Moses Lutaakome

2015-01-01

Background: Despite the recent innovations in tuberculosis (TB) and multi-drug resistant TB (MDR-TB) diagnosis, culture remains vital for difficult-to-diagnose patients, baseline and end-point determination for novel vaccines and drug trials. Herein, we share our experience of establishing a BSL-3

Van die Gasredakteur

African Journals Online (AJOL)

cherish and teach.'1. Die Fakulteit Geneeskunde van die Universiteit van die Oranje-Vrystaat het pragtig gegroei ge- durende die eerste 21 jaar van sy bestaan. Die entoesiasme, doelgerigtheid, harde werk en inisia- tiewe van 'n groot aantal persone was hiervoor verantwoordelik. 'If we see a bit more clearly than they, it is ...

Suid-Afrikaanse romans in Afrikaans sowel as Engels; soms bloot ...

African Journals Online (AJOL)

8 Apr 2016 ... word in sommige van die collages wat elke hoofstuk voorafgaan. Benewens die gesprek met ouer, meer literêre werke, kan Botha se roman ook andersyds beskou word as deel van 'n bepaalde kontemporêre literêre beweging, waar- êre literêre beweging, waar- re literêre beweging, waar- êre beweging ...

Options of ship discharge

Energy Technology Data Exchange (ETDEWEB)

NONE

2010-05-15

Environmental performance is a key design consideration for manufacturers of bulk handling machines, not least ship unloaders, with features being introduced to minimise dust and noise pollution. The article reports on developments in grab unloaders, slewing grabcranes and mobile grabcranes by manufacturers such as Konecrane, EMS-Tech, Liebherr-Werk Nenzing and Gottwald. 2 photos.

Valued Estonian Music CDs

Index Scriptorium Estoniae

2004-01-01

2002. aastal välja antud eesti muusika heliplaatidest Artur Kapp "Symphonische Werke", Eduard Tubin "Symphonies No.9, No.10 and No.11", "Estonian Preludes", "Eesti heliloojad. Hortus Musicus", "Eesti Muusika Päevad", "Tallinn Saxophone Quartet. Estonian Contemporary Music", "Triskele. Kolga-Jaani vaimulikud rahvalaulud", "Helmekaala. Linnupuu Anne", "Modern Fox mängib Raimond Valgret",

Prantsuse maastikuarhitektid Berliinist = French Landscape Architects from Berlin / Katrin Koov

Index Scriptorium Estoniae

Koov, Katrin, 1973-

2003-01-01

Berliinis töötavad prantsuse maastikuarhitektid Veronique Faucheur, Marc Pouzol ja Laurent Dugua büroost le balto kujundavad Tallinnasse "Heliose" kino hoovi valgusaia. Valminud on projekti I etapp, aed valmib 2004. a. kevadeks. Arhitektide loomingust (projekt "Ajutised Aiad" ja Kunst-Werke aed Berliinis, Palais de Tokyo aed Pariisis, Padula kloostri aed Itaalias)

15 Resensie Fourie 03 WEB.pmd

African Journals Online (AJOL)

Owner

regverdige kans te gee en die gaping in die resepsie van sy werk te vul. Teen hierdie agtergrond en die doelstelling van die versameling moet dit egter gestel word dat die mederedakteurskap van Brink se eggenote Szczurek 'n mens ietwat onge- maklik laat voel––juis omdat die bundel uitdruklik ingaan teen die ingeteelde ...

Browse Title Index

African Journals Online (AJOL)

Items 51 - 100 of 317 ... Vol 4, No 4 (2010), Diffuse bony involvement in disseminated BCG disease in a patient with possible severe combined immune deficiency (SCID), Abstract PDF. N Khan, I van de Werke, F Ismail. Vol 7, No 3 (2013), Dilemmas of telling bad news: Paediatric palliative care providers' experiences in rural ...

D r . A. S iz oo , Christenen in die Antieke Wereld, JH Kok, Kampen ...

African Journals Online (AJOL)

Test

Aan die hand van 'n aantal sketse wat deeglik gefundeer is in die oud-christelike bronnemateriaal, bied hierdie bekende skrywer 'n blik in die alledaagse lewe van die vroeë Christendom. Hoewel populêr geskrywe en maklik verstaanbaar vir die nie-teoloog, is die werk in die gebruik van sy bronne en sy gevolgtrekkinge ...

DIE ROL VAN DIE TAALWETENSKAP IN DIE ONTWIKKELING VAN ...

African Journals Online (AJOL)

aanslag op die sogenaamde "Intentional Fallacy", heelwat verder. n. Mens sou hier eintlik ook op die invloed van Lacan se toepassing van. De Sacs sure op Freud moet wys, en op Macherey se Theory of Literary. Production. Barthes is naamlik besig om repressie teen te werk, en die teks as produksieproses in stede van ...

A. S. G O. C ullmann , Der Staat im Neuen Testament. J. C . B. Mohr ...

African Journals Online (AJOL)

Test

Dit is nietemin nie die eerste maal dat Cullmann oor die onderwerp skryf nie. Vroeër het daar reeds van hom verskyn, Konigsherrschaft. Christ und Kirche im Neuen Testament, en effens later, Die ersten christliche. Qlaubensbekenntnisse en betreklik onlangs, Christus und die Zeit. In al hierdie werke raak hy fasette van die ...

On-site and off-site activities

International Nuclear Information System (INIS)

Martin, H.D.

1986-01-01

Design principles for NPP training programs. Effects of NPP contracts. Effects of domestic industrial activities. The role of international bodies. Requirements for on-site training. Training abroad, technical, financial and social aspects. Training center on-site, an evaluation. (orig.)

Region 9 NPL Sites (Superfund Sites 2013)

Science.gov (United States)

NPL site POINT locations for the US EPA Region 9. NPL (National Priorities List) sites are hazardous waste sites that are eligible for extensive long-term cleanup under the Superfund program. Eligibility is determined by a scoring method called Hazard Ranking System. Sites with high scores are listed on the NPL. The majority of the locations are derived from polygon centroids of digitized site boundaries. The remaining locations were generated from address geocoding and digitizing. Area covered by this data set include Arizona, California, Nevada, Hawaii, Guam, American Samoa, Northern Marianas and Trust Territories. Attributes include NPL status codes, NPL industry type codes and environmental indicators. Related table, NPL_Contaminants contains information about contaminated media types and chemicals. This is a one-to-many relate and can be related to the feature class using the relationship classes under the Feature Data Set ENVIRO_CONTAMINANT.

On-Site or Off-Site Renewable Energy Supply Options?

DEFF Research Database (Denmark)

Marszal, Anna Joanna; Heiselberg, Per; Jensen, Rasmus Lund

2012-01-01

The concept of a Net Zero Energy Building (Net ZEB) encompasses two options of supplying renewable energy, which can offset energy use of a building, in particular on-site or off-site renewable energy supply. Currently, the on-site options are much more popular than the off-site; however, taking...... into consideration the limited area of roof and/or façade, primarily in the dense city areas, the Danish weather conditions, the growing interest and number of wind turbine co-ops, the off-site renewable energy supply options could become a meaningful solution for reaching ‘zero’ energy goal in the Danish context...... five technologies, i.e., two on-site options: (1) photovoltaic, (2) micro combined heat and power, and three off-site options: (1) off-site windmill, (2) share of a windmill farm and (3) purchase of green energy from the 100% renewable utility grid. The results indicate that in case of the on...

How should we deal with ethics in student supervision?

Directory of Open Access Journals (Sweden)

Ellen Hooyberghs

2012-06-01

Dat supervisie essentieel is binnen het beroep van sociaal werk, daar zijn sociaal werkers het al langer over eens. Supervisie krijgt binnen de opleiding sociaal werk dan ook een belangrijke plaats. In supervisie leren studenten (eerste werkervaringen te analyseren, eigen indrukken en gevoelens te onderzoeken en hun visie op het werkveld te verruimen en dit onder begeleiding van een supervisor. Studenten leren tevens de reeds verworven theorie om te zetten in de praktijk. Voor het merendeel van de studenten is dit geen eenvoudige klus. Zij hebben dan vele morele en ethische vragen over hun handelen. Aangezien de waarden en normen binnen het sociaal werkveld niet statisch en eenduidig zijn, is het soms ook erg verwarrend wat nu juist “juist” handelen is. Binnen een supervisiegroep kunnen hier bij de verschillende studenten en supervisor meerdere meningen over bestaan. Daarom wordt de methodiek “Ethische cirkels in sociaal werk” toegelicht in dit artikel. Deze methode kan een houvast bieden voor studenten en supervisor om aan de slag te gaan met ethische vragen.

Nuclear power plant site evaluation using site population-meterology factor

International Nuclear Information System (INIS)

Rho, B.H.; Kang, C.H.

1982-01-01

In this paper, as a site evaluation technique, SPNF(Site Population Neteorology Factor) which is modified from SPF(Site Population Factor) of the USNRC model, is defined from site population and meteorology data in order to consider the radiological impacts to the population at large from the atmospheric dispersion of the radioactive effluents released during routine plant operation as well as accidental conditions. The SPMF model proved its propriety from the comparison of SPMF and SPF for Kori site. The relative suitability of Korean sites to the U.S. sites have been also examined using SPF. (Author)

Analytic equivalence relations and the forcing method

Czech Academy of Sciences Publication Activity Database

Zapletal, Jindřich

2013-01-01

Roč. 19, č. 4 (2013), s. 473-490 ISSN 1079-8986 R&D Projects: GA AV ČR IAA100190902 Institutional support: RVO:67985840 Keywords : closed sets * ideals Subject RIV: BA - General Mathematics Impact factor: 0.917, year: 2013 http://projecteuclid.org/euclid.bsl/1388953942

Die hervertolking van die paradigma in verband met die ...

African Journals Online (AJOL)

Kerkorde van De Mist en die Algemene Reglement van 1816, wat onderskeidelik vir die Kaapse Kerk en die .... Een van die eerstes was Sam Freiherr von Pufendorf (1632-1694) wat in sy werk De habitu religionis ..... Koning was weer aan bewind (vgl Diepenhorst sj:74w; De Visser 1926/1927 lll:202w). 43.1 JD Janssen ...

Die woordeboek vir meganiese ingenieurs: Vorderingsverslag

Directory of Open Access Journals (Sweden)

Editorial Office

1990-07-01

Full Text Available Die komitee van die Nasionale Vakterminologiediens (NVD wat ’n woordeboek vir meganiese ingenieurswese saamstel en in Januarie 1986 met sy werksaamhede begin het, maak goeie vordering. Die dag-tot-dag-werk word deur 'n redaksiekomitee behartig wat twee keer maandeliks vergader en uit verteenwoordigers van universiteite, SAVD, YSKOR, SABS en ander instansies bestaan.

Financial implications for built environment consultants working at ...

African Journals Online (AJOL)

Konsultante in die boubedryf van Suid-Afrika loop finansiële risiko's as gevolg van kliënte se verwagtinge om sekere fases van werk te voltooi teen 'n risiko. Konsultante voltooi dus projekte teen 'n risiko met die hoop op vergoeding in die lang duur. 'n Beskrywende opname is gedoen onder 'n verskeidenheid professionele ...

Optical measurement of surface roughness in manufacturing

Energy Technology Data Exchange (ETDEWEB)

Brodmann, R.

1984-11-01

The measuring system described here is based on the light-scattering method, and was developed by Optische Werke G. Rodenstock, Munich. It is especially useful for rapid non-contact monitoring of surface roughness in production-related areas. This paper outlines the differences between this system and the common stylus instrument, including descriptions of some applications in industry.

Völker strafen

Directory of Open Access Journals (Sweden)

Henning Radtke

2004-01-01

Full Text Available Rezensierte Werke:William A. Schabas, Der Genozid im Völkerrecht, Hamburg: Hamburger Edition HIS 2003, 792 S., ISBN 3-930908-88-3; Gerhard Werle, Völkerstrafrecht (unter Mitarbeit von Florian Jeßberger, Wulf Burchards, Barbara Lüders, Stephan Meseke, Volker Nerlich, Tübingen: Mohr Siebeck 2003, 553 S., ISBN 3-16-148087-2

Missionale kerkwees

African Journals Online (AJOL)

Test

Paul Hooker (2008) werk die begrip soos volg uit: ...... Brunner, E., 1960, Die christliche Lehre von der Kirche, vom Glauben und von ..... P.S., 1960, Images of the church in the New Testament, Westminister John Knox, ... Testament in the Olivétan Bible of 1535', Koers 66(1/2) 1–22. http://dx.doi. .... Harper Collins, New York.

Volkslinguïstiek en dialectlexico¬grafie in de zuidelijke Nederlanden

African Journals Online (AJOL)

Riette Ruthven

mag dat als bewijs gelden dat de notie in het Nederlandse taalgebied zo goed als onbekend is. 'Folk linguistics' is blijkbaar wel bekend in de Angelsaksische wereld, voor een groot deel dank zij het werk van Preston en Niedzielski.2 Met de term wordt het geheel bedoeld van volkse opinies en attitudes tegenover taal; het ...

Superfund and Toxic Release Inventory Sites - MDC_ContaminatedSite

Data.gov (United States)

NSGIC Local Govt | GIS Inventory — A point feature class of open DERM Contaminated sites - see phase code for status of site. Contaminated sites identifies properties where environmental contamination...

Language lateralization of hearing native signers: A functional transcranial Doppler sonography (fTCD) study of speech and sign production.

Science.gov (United States)

Gutierrez-Sigut, Eva; Daws, Richard; Payne, Heather; Blott, Jonathan; Marshall, Chloë; MacSweeney, Mairéad

2015-12-01

Neuroimaging studies suggest greater involvement of the left parietal lobe in sign language compared to speech production. This stronger activation might be linked to the specific demands of sign encoding and proprioceptive monitoring. In Experiment 1 we investigate hemispheric lateralization during sign and speech generation in hearing native users of English and British Sign Language (BSL). Participants exhibited stronger lateralization during BSL than English production. In Experiment 2 we investigated whether this increased lateralization index could be due exclusively to the higher motoric demands of sign production. Sign naïve participants performed a phonological fluency task in English and a non-sign repetition task. Participants were left lateralized in the phonological fluency task but there was no consistent pattern of lateralization for the non-sign repetition in these hearing non-signers. The current data demonstrate stronger left hemisphere lateralization for producing signs than speech, which was not primarily driven by motoric articulatory demands. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

[Effectiveness of Dialectical Behavior Therapy (DBT) in an outpatient clinic for borderline personality disorders - impact of medication use and treatment costs].

Science.gov (United States)

Richter, Christoph; Heinemann, Brigitte; Kehn, Mathias; Steinacher, Bruno

2014-04-01

Investigation of the clinical effectiveness of dialectical behavioral therapy in a day clinic setting (DBT-DC) for borderline personality disorders (BPD), and impact of medication and daily costs. In a prospective, naturalistic, open and uncontrolled design BPD patients were enclosed in a 12-week DBT-DC. This DBT-program was certified by the German network of DBT. We collected data from the Symptom Checklist (SCL-90), the Beck Depression Inventory (BDI) and the Borderline Symptom List 95 (BSL-95) in the first and at the end of the 11th week. The concomitant medication and its changes were described. 31 cases were included (9 drop-outs: 29 %). The average age was 33.3 years (18 - 52, SD = 10.6). 21 females and one male completed the program. There was no relationship between changes of BDI, SCL-90 and BSL-95 scores (p therapy. © Georg Thieme Verlag KG Stuttgart · New York.

A novel steel RE-borosulphurizing and mechanical properties of the produced RE-borosulfide layer

Science.gov (United States)

Wang, Dong; Li, Yun-dong; Zhang, Xiu-li

2013-07-01

In this study, 45# carbon steels were boronized, borosulphurized and RE-borosulphurized at 950 °C for 6 h, respectively. The samples were then characterized by scanning electron microscopy, X-ray diffraction, Auger electron spectroscopy, microhardness tester and ring-on-block wear tester. It has shown that the diffusion front (the interface between the diffusion layer and the substrate) of the boride layer (BL) and the boro-sulfide layer (BSL) is saw tooth shape, while the diffusion front of the RE-boro-sulfide layer (RBSL) is flat. Compared with BSL layer, RBSL layer has a smaller and more uniform grain size, and a flatter hardness gradient from the surface to the diffusion front. The RBSL layer, consisting of an outer layer (from surface to 30 μm) mainly composed of Fe-B and an inner layer (from 30 μm to the diffusion front) mainly composed of Fe-S, has the best wear resistance and the most sufficient adhesion among those three.

Assembly and Function of the Bacillus anthracis S-Layer.

Science.gov (United States)

Missiakas, Dominique; Schneewind, Olaf

2017-09-08

Bacillus anthracis, the anthrax agent, is a member of the Bacillus cereus sensu lato group, which includes invasive pathogens of mammals or insects as well as nonpathogenic environmental strains. The genes for anthrax pathogenesis are located on two large virulence plasmids. Similar virulence plasmids have been acquired by other B. cereus strains and enable the pathogenesis of anthrax-like diseases. Among the virulence factors of B. anthracis is the S-layer-associated protein BslA, which endows bacilli with invasive attributes for mammalian hosts. BslA surface display and function are dependent on the bacterial S-layer, whose constituents assemble by binding to the secondary cell wall polysaccharide (SCWP) via S-layer homology (SLH) domains. B. anthracis and other pathogenic B. cereus isolates harbor genes for the secretion of S-layer proteins, for S-layer assembly, and for synthesis of the SCWP. We review here recent insights into the assembly and function of the S-layer and the SCWP.

Umatilla Satellite and Release Sites Project : Final Siting Report.

Energy Technology Data Exchange (ETDEWEB)

Montgomery, James M.

1992-04-01

This report presents the results of site analysis for the Umatilla Satellite and Release Sites Project. The purpose of this project is to provide engineering services for the siting and conceptual design of satellite and release facilities for the Umatilla Basin hatchery program. The Umatilla Basin hatchery program consists of artificial production facilities for salmon and steelhead to enhance production in the Umatilla River as defined in the Umatilla master plan approved in 1989 by the Northwest Power Planning Council. Facilities identified in the master plan include adult salmon broodstock holding and spawning facilities, facilities for recovery, acclimation, and/or extended rearing of salmon juveniles, and development of river sites for release of hatchery salmon and steelhead. The historic and current distribution of fall chinook, summer chinook, and coho salmon and steelhead trout was summarized for the Umatilla River basin. Current and future production and release objectives were reviewed. Twenty seven sites were evaluated for the potential and development of facilities. Engineering and environmental attributes of the sites were evaluated and compared to facility requirements for water and space. Site screening was conducted to identify the sites with the most potential for facility development. Alternative sites were selected for conceptual design of each facility type. A proposed program for adult holding facilities, final rearing/acclimation, and direct release facilities was developed.

Site decontamination

International Nuclear Information System (INIS)

Bicker, A.E.

1981-01-01

Among the several DOE sites that have been radiologically decontaminated under the auspices of the Nevada Operations Office are three whose physical characteristics are unique. These are the Tatum Dome Test Site (TDTS) near Hattiesburg, Mississippi; a location of mountainous terrain (Pahute Mesa) on the Nevada Test Site; and the GNOME site near Carlsbad, New Mexico. In each case the contamination, the terrain, and the climate conditions were different. This presentation includes a brief description of each site, the methods used to perform radiological surveys, the logistics required to support the decontamination (including health physics and sample analysis), and the specific techniques used to reduce or remove the contamination

Bedrock hydrogeology Forsmark. Site descriptive modelling, SDM-Site Forsmark

Energy Technology Data Exchange (ETDEWEB)

Follin, Sven (SF GeoLogic AB, Taeby (Sweden))

2008-12-15

The Swedish Nuclear Fuel and Waste Management Company (SKB) has conducted site investigations at two different locations, the Forsmark and Laxemar-Simpevarp areas, with the objective of siting a final repository for spent nuclear fuel according to the KBS-3 concept. Site characterisation should provide all data required for an integrated evaluation of the suitability of the investigated site and an important component in the characterisation work is the development of a hydrogeological model. The hydrogeological model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It also provides input to the safety assessment. Another important use of the hydrogeological model is in the environmental impact assessment. This report presents the understanding of the hydrogeological conditions of the bedrock at Forsmark reached following the completion of the surface-based investigations and provides a summary of the bedrock hydrogeological model and the underlying data supporting its development. It constitutes the main reference on bedrock hydrogeology for the site descriptive model concluding the surface-based investigations at Forsmark, SDM-site, and is intended to describe the hydraulic properties and hydrogeological conditions of the bedrock at the site and to give the information essential for demonstrating understanding

78 FR 2910 - Airworthiness Directives; GROB-WERKE Airplanes

Science.gov (United States)

2013-01-15

... arms on several Grob G 115 airplanes, which could result in failure of the part and consequent loss of...., Washington, DC 20590. Hand Delivery: U.S. Department of Transportation, Docket Operations, M-30, West... verbal contact we receive about this proposed AD. Discussion The European Aviation Safety Agency (EASA...

78 FR 23112 - Airworthiness Directives; Grob-Werke Airplanes

Science.gov (United States)

2013-04-18

... material at the FAA, call (816) 329-4148. FOR FURTHER INFORMATION CONTACT: Taylor Martin, Aerospace...: (816) 329-4138; fax: (816) 329-4090; email: taylor[email protected] . SUPPLEMENTARY INFORMATION... to detect cracks and prevent the part from failing. (f) Actions and Compliance Unless already done...

Siglenverzeichnis und Abkürzungen der Werke Wittgensteins

OpenAIRE

2017-01-01

AüL Aufzeichnungen über Logik BB Aufzeichnungen über Logik BGM Bemerkungen über die Grundlagen der Mathematik BLF Bemerkungen über logische Form BPP Bemerkungen über die Philosophie der Psychologie BüF Bemerkungen über die Farben PB Philosophische Bemerkungen PG Philosophische Grammatik PU Philosophische Untersuchungen T Tractatus Logico-philosophicus TB Tagebücher 1914-1916 ÜG Über Gewißheit V&G Vorlesungen und Gespräche über Ästhetik, Psychoanalyse und religiösen Glauben WWK Wittgenstein un...

Titan en Christiaan. Huygens in werk en leven

NARCIS (Netherlands)

Dijksterhuis, Fokko J.

2000-01-01

In three respects Christiaan Huygens (1629-1695) poses a biographical problem. Unlike contemporaries he hardly ever reflected upon what he thought he was doing; his versatility makes it hard to gain a balanced view of what he was doing; his personality seems almost absent from his writings. In the

Social Media Sites

Science.gov (United States)

Media Sites Site Registration Contact Us Search AF.mil: Home > AF Sites > Social Media Sites Social Media Welcome to the Air Force social media directory! The directory is a one-stop shop of official Air Force social media pages across various social media sites. Social media is all about

Hypoglycemic and anti-hyperglycemic activity of Triphalādi granules in mice

Directory of Open Access Journals (Sweden)

Ankush Gunjal

2016-01-01

Conclusion: Triphalādi granules have significant hypoglycemic and anti-hyperglycemic activity in mice with minimal effect on BSL below normal range. The studies suggest the potential role of Triphalādi granules as an alternative adjuvant therapy in diabetic individuals for the control of the blood glucose level.

Comprehending Sentences with the Body: Action Compatibility in British Sign Language?

Science.gov (United States)

Vinson, David; Perniss, Pamela; Fox, Neil; Vigliocco, Gabriella

2017-01-01

Previous studies show that reading sentences about actions leads to specific motor activity associated with actually performing those actions. We investigate how sign language input may modulate motor activation, using British Sign Language (BSL) sentences, some of which explicitly encode direction of motion, versus written English, where motion…

A universal next generation sequencing protocol to generate non-infectious barcoded cDNA libraries from high containment RNA viruses

Science.gov (United States)

Several biosafety level (BSL)-3/4 pathogens are high consequence, single-stranded RNA viruses and their genomes, when introduced into permissive cells, are infectious. Moreover many of these viruses are Select Agents (SAs), and their genomes are also considered SAs. For this reason cDNAs and/or th...

Site operations

International Nuclear Information System (INIS)

House, W.B.; Ebenhack, D.G.

1989-01-01

This chapter is a discussion of the management and operations practices used at the Barnwell Waste Management Facility in Barnwell, SC. The following topics are discussed: (1) Waste receiving and inspection, including manifest and certificates of compliance, radiological surveys, disposition of nonconforming items, and decontamination and disposition of secondary waste streams; (2) Waste disposal, including Title 10 CFR 61 requirements, disposal area evaluations, shipment offloading, container emplacement, and radiation protection; (3) Trench closure, including trench backfilling, trench capping, and permanent markers; (4) Site maintenance and stabilization, including trench maintenance, surface water management, and site closure activities; (5) Site monitoring programs, including operational monitoring, and environmental monitoring program; (6) Personnel training and qualifications, including basic training program, safety training program, special skills training, and physical qualifications; (7) Records management, including waste records, personnel training records, personnel dosimetry records, site monitoring records, trench qualification and construction records, and site drawings and stabilization records; (8) Site security; (9) Emergency response plans; and (10) Quality assurance

Biosafety level-2 laboratory diagnosis of Zaire Ebola virus disease imported from Liberia to Nigeria

Directory of Open Access Journals (Sweden)

Olumuyiwa B. Salu

2016-10-01

Full Text Available Introduction: Global travel is an efficient route of transmission for highly infectious pathogens and increases the chances of such pathogens moving from high disease-endemic areas to new regions. We describe the rapid and safe identification of the first imported case of Ebola virus disease in a traveler to Lagos, Nigeria, using conventional reverse transcription polymerase chain reaction (RT-PCR in a biosafety level (BSL-2 facility. Case presentation: On 20 July 2014, a traveler arrived from Liberia at Lagos International Airport and was admitted to a private hospital in Lagos, with clinical suspicion of Ebola virus disease. Methodology and Outcome: Blood and urine specimens were collected, transported to the Virology Unit Laboratory at the College of Medicine, University of Lagos, and processed under stringent biosafety conditions for viral RNA extraction. RT-PCR was set-up to query the Ebola, Lassa and Dengue fever viruses. Amplicons for pan-filoviruses were detected as 300 bp bands on a 1.5% agarose gel image; there were no detectable bands for Lassa and Dengue viral RNA. Nucleotide BLAST and phylogenetic analysis of sequence data of the RNA-dependent RNA polymerase (L gene confirmed the sequence to be Zaire ebolavirus (EBOV/Hsap/ NGA/2014/LIB-NIG 01072014; Genbank: KM251803.1. Conclusion: Our BSL-2 facility in Lagos, Nigeria, was able to safely detect Ebola virus disease using molecular techniques, supporting the reliability of molecular detection of highly infectious viral pathogens under stringent safety guidelines in BSL-2 laboratories. This is a significant lesson for the many under-facilitated laboratories in resource-limited settings, as is predominantly found in sub-Saharan Africa.

From gesture to sign language: conventionalization of classifier constructions by adult hearing learners of British Sign Language.

Science.gov (United States)

Marshall, Chloë R; Morgan, Gary

2015-01-01

There has long been interest in why languages are shaped the way they are, and in the relationship between sign language and gesture. In sign languages, entity classifiers are handshapes that encode how objects move, how they are located relative to one another, and how multiple objects of the same type are distributed in space. Previous studies have shown that hearing adults who are asked to use only manual gestures to describe how objects move in space will use gestures that bear some similarities to classifiers. We investigated how accurately hearing adults, who had been learning British Sign Language (BSL) for 1-3 years, produce and comprehend classifiers in (static) locative and distributive constructions. In a production task, learners of BSL knew that they could use their hands to represent objects, but they had difficulty choosing the same, conventionalized, handshapes as native signers. They were, however, highly accurate at encoding location and orientation information. Learners therefore show the same pattern found in sign-naïve gesturers. In contrast, handshape, orientation, and location were comprehended with equal (high) accuracy, and testing a group of sign-naïve adults showed that they too were able to understand classifiers with higher than chance accuracy. We conclude that adult learners of BSL bring their visuo-spatial knowledge and gestural abilities to the tasks of understanding and producing constructions that contain entity classifiers. We speculate that investigating the time course of adult sign language acquisition might shed light on how gesture became (and, indeed, becomes) conventionalized during the genesis of sign languages. Copyright © 2014 Cognitive Science Society, Inc.

Confidence assessment. Site-descriptive modelling SDM-Site Laxemar

International Nuclear Information System (INIS)

2009-06-01

The objective of this report is to assess the confidence that can be placed in the Laxemar site descriptive model, based on the information available at the conclusion of the surface-based investigations (SDM-Site Laxemar). In this exploration, an overriding question is whether remaining uncertainties are significant for repository engineering design or long-term safety assessment and could successfully be further reduced by more surface-based investigations or more usefully by explorations underground made during construction of the repository. Procedures for this assessment have been progressively refined during the course of the site descriptive modelling, and applied to all previous versions of the Forsmark and Laxemar site descriptive models. They include assessment of whether all relevant data have been considered and understood, identification of the main uncertainties and their causes, possible alternative models and their handling, and consistency between disciplines. The assessment then forms the basis for an overall confidence statement. The confidence in the Laxemar site descriptive model, based on the data available at the conclusion of the surface based site investigations, has been assessed by exploring: - Confidence in the site characterization data base, - remaining issues and their handling, - handling of alternatives, - consistency between disciplines and - main reasons for confidence and lack of confidence in the model. Generally, the site investigation database is of high quality, as assured by the quality procedures applied. It is judged that the Laxemar site descriptive model has an overall high level of confidence. Because of the relatively robust geological model that describes the site, the overall confidence in the Laxemar Site Descriptive model is judged to be high, even though details of the spatial variability remain unknown. The overall reason for this confidence is the wide spatial distribution of the data and the consistency between

Confidence assessment. Site-descriptive modelling SDM-Site Laxemar

Energy Technology Data Exchange (ETDEWEB)

2008-12-15

The objective of this report is to assess the confidence that can be placed in the Laxemar site descriptive model, based on the information available at the conclusion of the surface-based investigations (SDM-Site Laxemar). In this exploration, an overriding question is whether remaining uncertainties are significant for repository engineering design or long-term safety assessment and could successfully be further reduced by more surface-based investigations or more usefully by explorations underground made during construction of the repository. Procedures for this assessment have been progressively refined during the course of the site descriptive modelling, and applied to all previous versions of the Forsmark and Laxemar site descriptive models. They include assessment of whether all relevant data have been considered and understood, identification of the main uncertainties and their causes, possible alternative models and their handling, and consistency between disciplines. The assessment then forms the basis for an overall confidence statement. The confidence in the Laxemar site descriptive model, based on the data available at the conclusion of the surface based site investigations, has been assessed by exploring: - Confidence in the site characterization data base, - remaining issues and their handling, - handling of alternatives, - consistency between disciplines and - main reasons for confidence and lack of confidence in the model. Generally, the site investigation database is of high quality, as assured by the quality procedures applied. It is judged that the Laxemar site descriptive model has an overall high level of confidence. Because of the relatively robust geological model that describes the site, the overall confidence in the Laxemar Site Descriptive model is judged to be high, even though details of the spatial variability remain unknown. The overall reason for this confidence is the wide spatial distribution of the data and the consistency between

Siting guidelines and their role in repository site selection

International Nuclear Information System (INIS)

Hanlon, C.L.

1985-01-01

The first requirement of the Nuclear Waste Policy Act was for the Secretary of Energy to issue general guidelines for siting repositories. The guidelines were to specify detailed geologic considerations that would be the primary criteria for the selection of sites in various host rocks, as well as factors that would qualify or disqualify any site from development as a repository. These guidelines were clearly intended to provide not only the framework for the siting program but also the stimulus for establishing effective communication and consultation among the parties involved in the program. The Act further required that the guidelines be a factor in the development of all future decision documents of the Office of Civilian Radioactive Waste Management, including the environmental assessments that would accompany the nomination of sites for characterization, the site-characterization plans that are to be prepared before the sinking of exploratory shafts at any candidate site, and the environmental impact statement that is to support the recommendation of a site for development as a repository. More than two years after its passage, the intention of the Act for the guidelines has been realized. Concurred in by the Nuclear Regulatory Commission on June 22, 1984, and issued by the Department in November 1984, the guidelines include postclosure technical guidelines that apply to conditions governing the long-term performance of the repository system; preclosure technical guidelines that apply to conditions governing the siting, construction, operation, and closure of the repository; and system guidelines whose objective is to ensure that the regulatory requirements of the Environmental Protection Agency and the Nuclear Regulatory Commission are met

SiteGuide: An example-based approach to web site development assistance

NARCIS (Netherlands)

Hollink, V.; de Boer, V.; van Someren, M.; Filipe, J.; Cordeiro, J.

2009-01-01

We present ‘SiteGuide’, a tool that helps web designers to decide which information will be included in a new web site and how the information will be organized. SiteGuide takes as input URLs of web sites from the same domain as the site the user wants to create. It automatically searches the pages

Voorwoord

Directory of Open Access Journals (Sweden)

D.F.M. Strauss

2011-06-01

Full Text Available Om ’n Festschrift ter ere van die akademiese werk van ’n kollega en medewetenskaplike te publiseer, is sekerlik een van die mees lonende intellektuele gebeurtenisse wat so ’n akademikus kan ervaar. Dit is daarom ook ’n besondere voorreg om die taak opgedra te word om ’n Voorwoord vir hierdie Festschrift te skryf.

Gerhard Ebeling oor geloof

African Journals Online (AJOL)

29 Jul 2016 ... oor die saak wat ter tafel is. Polemiek oor ander teoloë se standpunte vorm nie deel van Ebeling se werk nie en direkte teologiese debat met ander is skaars in sy oeuvre. Ebeling dink radikaal krities met 'n fyn hermeneutiese aanvoeling vir die lewe as denkkonteks eerder as dat hy die een of ander sisteem ...

Ek wil hier graag van die geleentheid gebruik maak am die ...

African Journals Online (AJOL)

die wildlewe am van die jagters nie eers mel- ding te maak nie en in Lucas se werk kan hulle ure van genot deurbring. Wat ons veral in Lucas se publikasie interes- seer is sy deelname aan die agste grensoor~' log (1850-1853), sy aantekeninge in verband met die slag by Berea (20 Oesember 1852) en sy indrukke van ...

Die metafoor by Breyten Breytenbach

African Journals Online (AJOL)

Owner

23 Jun 2009 ... metafories, of spesifiek verwysend, te werk gegaan is. Tyd sou mens die hoofmotief van die bundel noem, tyd en geheue wat verbygaan: 1 en 2; en die einde van die storie wat gekom het: “fluit-fluit my storie is uit”. (Die tema van verbygaan word weer opgeneem in 8 en 9: die stories wat nooit meer gehoor ...

Land van skedels. Nicola Hanekom. Pretoria: Protea Boekhuis ...

African Journals Online (AJOL)

tema is, soos te verwagte in 'n stuk wat werk met historiese materiaal, die tema van onthou. Reeds in die “skrywersnota” stel Nicola Hanekom dat “[o]ns moet altyd onthou om te onthou. Ons vergeet dit soms. Ons moet die dier binne ons in toom hou en probeer luister na die engele in die chaos”. Die gevaar van vergeet is.

Change and Continuity in Librarianship: Approaching the Twenty-First Century. Proceedings of the 40th Military Librarians Workshop, 20-22 November 1996, Annapolis, Maryland,

Science.gov (United States)

1996-11-01

Novembecr 1996 Arinarolis, Maryland1 rDIO QUALMTY DZEOTN I VIBYKUTON UrtAIK=yg A Change and Continuity in Librarianship : Approaching the Twenty-first...speakers Walt Crawford (Keynote), speaking on "Millennial Librarianship ;" Dr. Keith Swigger, Dean of the Graduate School of Library and Information...1 --Richard Hume Werking Millennial Librarianship : Maintaining the Mix and Avoiding the Hype .................. 2 --Walt Crawford

Feedback from performance assessment to site characterisation. The SITE-94 example

International Nuclear Information System (INIS)

Dverstorp, B.; Geier, J.

1999-01-01

Interaction and information exchange between site characterisation and performance assessment are key features of any successful radioactive waste management programme. Some examples are presented of the types of feedback that can be offered from performance assessment to site characterisation, based on SKI's most recent performance assessment project, SITE-94. SITE-94 in Sweden was an assessment of a hypothetical repository for spent nuclear fuel, based on real data gathered in the surface-based investigation of the Aespoe Hard Rock Laboratory site. Examples of feedback are given concerning quality control of data and site investigation procedures, identification of key parameters for the performance assessment, use of models for planning and evaluation of a site investigation, data sampling strategies, and guidance on future priorities for further development of site investigation methods. Because site characterisation serves multiple purposes, including provision of data for repository design and construction, it must account for and compromise among requirements from several lines of analyses in the performance assessment. (author)

Site characterization plan:

International Nuclear Information System (INIS)

1988-01-01

The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package;and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed

SiteFind: A software tool for introducing a restriction site as a marker for successful site-directed mutagenesis

Directory of Open Access Journals (Sweden)

Evans Paul M

2005-12-01

Full Text Available Abstract Background Site-directed mutagenesis is a widely-used technique for introducing mutations into a particular DNA sequence, often with the goal of creating a point mutation in the corresponding amino acid sequence but otherwise leaving the overall sequence undisturbed. However, this method provides no means for verifying its success other than sequencing the putative mutant construct: This can quickly become an expensive method for screening for successful mutations. An alternative to sequencing is to simultaneously introduce a restriction site near the point mutation in manner such that the restriction site has no effect on the translated amino acid sequence. Thus, the novel restriction site can be used as a marker for successful mutation which can be quickly and easily assessed. However, finding a restriction site that does not disturb the corresponding amino acid sequence is a time-consuming task even for experienced researchers. A fast and easy to use computer program is needed for this task. Results We wrote a computer program, called SiteFind, to help us design a restriction site within the mutation primers without changing the peptide sequence. Because of the redundancy of genetic code, a given peptide can be encoded by many different DNA sequences. Since the list of possible restriction sites for a given DNA sequence is not always obvious, SiteFind automates this task. The number of possible sequences a computer program must search through increases exponentially as the sequence length increases. SiteFind uses a novel "moving window" algorithm to reduce the number of possible sequences to be searched to a manageable level. The user enters a nucleotide sequence, specifies what amino acid residues should be changed in the mutation, and SiteFind generates a list of possible restriction sites and what nucleotides must be changed to introduce that site. As a demonstration of its use, we successfully generated a single point mutation

Remaining Sites Verification Package for the 128-B-3 Burn Pit Site, Waste Site Reclassification Form 2006-058

Energy Technology Data Exchange (ETDEWEB)

L. M. Dittmer

2006-11-17

The 128-B-3 waste site is a former burn and disposal site for the 100-B/C Area, located adjacent to the Columbia River. The 128-B-3 waste site has been remediated to meet the remedial action objectives specified in the Remaining Sites ROD. The results of verification sampling demonstrated that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results of sampling at upland areas of the site also showed that residual contaminant concentrations are protective of groundwater and the Columbia River.

Site characterization plan:

International Nuclear Information System (INIS)

1988-01-01

The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in acordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and eveloping a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing prinicples, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed. 880 refs., 130 figs., 25 tabs

On multi-site damage identification using single-site training data

Science.gov (United States)

Barthorpe, R. J.; Manson, G.; Worden, K.

2017-11-01

This paper proposes a methodology for developing multi-site damage location systems for engineering structures that can be trained using single-site damaged state data only. The methodology involves training a sequence of binary classifiers based upon single-site damage data and combining the developed classifiers into a robust multi-class damage locator. In this way, the multi-site damage identification problem may be decomposed into a sequence of binary decisions. In this paper Support Vector Classifiers are adopted as the means of making these binary decisions. The proposed methodology represents an advancement on the state of the art in the field of multi-site damage identification which require either: (1) full damaged state data from single- and multi-site damage cases or (2) the development of a physics-based model to make multi-site model predictions. The potential benefit of the proposed methodology is that a significantly reduced number of recorded damage states may be required in order to train a multi-site damage locator without recourse to physics-based model predictions. In this paper it is first demonstrated that Support Vector Classification represents an appropriate approach to the multi-site damage location problem, with methods for combining binary classifiers discussed. Next, the proposed methodology is demonstrated and evaluated through application to a real engineering structure - a Piper Tomahawk trainer aircraft wing - with its performance compared to classifiers trained using the full damaged-state dataset.

Nevada Test Site Environmental Report 2005, Attachment A - Site Description

International Nuclear Information System (INIS)

Cathy A. Wills

2006-01-01

This appendix to the ''Nevada Test Site Environmental Report 2005'', dated October 2006 (DOE/NV/11718--1214; DOE/NV/25946--007) expands on the general description of the Nevada Test Site (NTS) presented in the Introduction. Included are subsections that summarize the site?s geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site which afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This appendix complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report

Nevada Test Site Environmental Report 2005, Attachment A - Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy A. Wills

2006-10-01

This appendix to the ''Nevada Test Site Environmental Report 2005'', dated October 2006 (DOE/NV/11718--1214; DOE/NV/25946--007) expands on the general description of the Nevada Test Site (NTS) presented in the Introduction. Included are subsections that summarize the site?s geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site which afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This appendix complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Siting Practices and Site Licensing Process for New Reactors in Canada

International Nuclear Information System (INIS)

Vos, Marcel de

2011-01-01

'Siting' in Canada is composed of Site Evaluation and Site Selection. As outlined in CNSC Regulatory Document RD-346 Site Evaluation for New Nuclear Power Plants (based on IAEA NS-R-3), prior to the triggering of the Environmental Assessment (EA) and licensing processes, the proponent is expected to use a robust process to characterize proposed sites over the full life cycle of the facility, and then develop a fully documented defense of the site selection case. This case forms the backbone for submissions in support of the EA and the application for a License to Prepare Site which will be reviewed by the CNSC and other applicable federal authorities. The Environmental Assessment process and License to Prepare Site in Canada do not require a proponent to select a specific design; however, CNSC does not accept a 'black box' approach to siting. CNSC balances the level of design information required with the extent of safety assurance desired for any designs being contemplated for the proposed site. Nevertheless, the design information submitted must be sufficient to justify the site as suitable for all future licensing stages. The depth of plant design information contributes significantly to the credibility of the applicant's case for both the EA and application for License to Prepare Site. The review process utilizes an assessment plan with defined review stages and timelines. The outcome of these reviews is a series of recommendations to a federal government appointed Joint Review Panel (which also serves as a panel of the 'Commission') which, following public hearings, renders a decision regarding the EA, and subsequently, the application for a License to Prepare Site. (author)

SITE-94. Site specific base data for the performance assessment

International Nuclear Information System (INIS)

Geier, J.; Tiren, S.; Dverstorp, B.; Glynn, P.

1996-06-01

This report documents the site specific base data that were available, and the utilization of these data within SITE-94. A brief summary is given of SKB's preliminary site investigations for the Aespoe Hard Rock Laboratory (HRL), which were the main source of site-specific data for SITE-94, and an overview is given of the field methods and instrumentation for the preliminary investigations. A compilation is given of comments concerning the availability and quality of the data for Aespoe, and specific recommendations are given for future site investigations. It was found that the HRL pre-investigations produced a large quantity of data which were, for the most part, of sufficient quality to be valuable for a performance assessment. However, some problems were encountered regarding documentation, procedural consistency, positional information, and storage of the data from the measurements. 77 refs, 4 tabs

Quantifying siting difficulty: a case study of US transmission line siting

Energy Technology Data Exchange (ETDEWEB)

Vajjhala, S.P. [Resources for the Future, Washington DC (United States); Fischbeck, P.S. [Carnegie Mellon University, Pittsburgh, PA (United States). Departments of Social and Decision Sciences and Engineering and Public Policy

2007-01-15

The worldwide demand for new energy infrastructures has been paralleled in recent years by the increasing difficulty of siting major facilities. Siting difficulty is the subject of widespread discussion, but because of the complexity of the problem, potential solutions are not obvious or well understood. This paper presents a two-step policy-level framework that first develops an empirical measure of siting difficulty and then qualitatively assesses its major causes. The approach is based on the creation and aggregation of four siting indicators that are independent of the common causes and localized effects of siting problems. The proposed framework is demonstrated for the case of US transmission line siting. Results of the analyses reveal significant variations in state siting difficulty and industry experts' perceptions of its dominant causes, with implications for the long-term success of Regional Transmission Organizations (RTOs) and knowledge transfer among siting professionals in the deregulated industry. (author)

SITE-2, Power Plant Siting, Cost, Environment, Seismic and Meteorological Effects

International Nuclear Information System (INIS)

Frigerio, N.A.; Habegger, L.J.; King, R.F.; Hoover, L.J.; Clark, N.A.; Cobian, J.M.

1977-01-01

1 - Description of problem or function: SITE2 is designed to (1) screen candidate energy facility sites or areas within an electric utility region, based on the region's physical and socioeconomic attributes, the planned facility's characteristics, and impact assessments, and (2) evaluate the cumulative regional impacts associated with alternate energy supply options and inter-regional energy import/export practices, specifically, comparison of different energy technologies and their regional distribution in clustered or dispersed patterns. 2 - Method of solution: The SITE2 methodology is based on the quantification of three major site-related vectors. A cost vector is determined which identifies site-specific costs, such as transmission costs, cooling costs as related to water availability, and costs of specific controls needed to protect the surrounding environment. An impact vector is also computed for each potential site, using models of health and environmental impacts incurred in areas adjacent to the site. Finally, a site attribute vector is developed which reflects such characteristics as population, seismic conditions, meteorology, land use, and local ecological systems. This vector can be used to eliminate certain sites because of their inability to satisfy specific constraints. These three vectors can be displayed as density maps and combined in a simple overlay approach, similar to that developed by I. L. McHarg in reference 2, to identify candidate sites. Alternatively, the vector elements can be computationally combined into a weighted sum to obtain quantitative indicators of site suitability

SITE-2, Power Plant Siting, Cost, Environment, Seismic and Meteorological Effects

Energy Technology Data Exchange (ETDEWEB)

Frigerio, N A [Environmental Impact Studies, Argonne National Laboratory 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Habegger, L J; King, R F; Hoover, L J [Energy and Environmental Systems Division, Argonne National Laboratory 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Clark, N A [Applied Mathematics Division, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Cobian, J M [Northwestern University, Evanston, Illinois 60201 (United States)

1977-08-01

1 - Description of problem or function: SITE2 is designed to (1) screen candidate energy facility sites or areas within an electric utility region, based on the region's physical and socioeconomic attributes, the planned facility's characteristics, and impact assessments, and (2) evaluate the cumulative regional impacts associated with alternate energy supply options and inter-regional energy import/export practices, specifically, comparison of different energy technologies and their regional distribution in clustered or dispersed patterns. 2 - Method of solution: The SITE2 methodology is based on the quantification of three major site-related vectors. A cost vector is determined which identifies site-specific costs, such as transmission costs, cooling costs as related to water availability, and costs of specific controls needed to protect the surrounding environment. An impact vector is also computed for each potential site, using models of health and environmental impacts incurred in areas adjacent to the site. Finally, a site attribute vector is developed which reflects such characteristics as population, seismic conditions, meteorology, land use, and local ecological systems. This vector can be used to eliminate certain sites because of their inability to satisfy specific constraints. These three vectors can be displayed as density maps and combined in a simple overlay approach, similar to that developed by I. L. McHarg in reference 2, to identify candidate sites. Alternatively, the vector elements can be computationally combined into a weighted sum to obtain quantitative indicators of site suitability.

Regional Sign Language Varieties in Contact: Investigating Patterns of Accommodation

Science.gov (United States)

Stamp, Rose; Schembri, Adam; Evans, Bronwen G.; Cormier, Kearsy

2016-01-01

Short-term linguistic accommodation has been observed in a number of spoken language studies. The first of its kind in sign language research, this study aims to investigate the effects of regional varieties in contact and lexical accommodation in British Sign Language (BSL). Twenty-five participants were recruited from Belfast, Glasgow,…

Association of transforming growth factor-ß3 gene polymorphism ...

African Journals Online (AJOL)

Genotyping for the TGF-β3 gene using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method and BslI restriction endonuclease showed a mutation in 294-bp fragment located on the fourth intron of chromosome 5. Polymorphism in TGF-β3 gene was significantly (P < 0.1) associated with ...

Report of early site suitability evaluation of the potential repository site at Yucca Mountain, Nevada; Yucca Mountain Site Characterization Project

Energy Technology Data Exchange (ETDEWEB)

Younker, J.L.; Andrews, W.B.; Fasano, G.A.; Herrington, C.C.; Mattson, S.R.; Murray, R.C. [Science Applications International Corp., Las Vegas, NV (United States); Ballou, L.B.; Revelli, M.A. [Lawrence Livermore National Lab., CA (United States); Ducharme, A.R.; Shephard, L.E. [Sandia National Labs., Albuquerque, NM (United States); Dudley, W.W.; Hoxie, D.T. [Geological Survey, Denver, CO (United States); Herbst, R.J.; Patera, E.A. [Los Alamos National Lab., NM (United States); Judd, B.R. [Decision Analysis Co., Portola Valley, CA (United States); Docka, J.A.; Rickertsen, L.D. [Weston Technical Associates, Washington, DC (United States)

1992-01-01

This study evaluated the technical suitability of Yucca Mountain, Nevada, as a potential site for a mined geologic repository for the permanent disposal of radioactive waste. The evaluation was conducted primarily to determine early in the site characterization program if there are any features or conditions at the site that indicate it is unsuitable for repository development. A secondary purpose was to determine the status of knowledge in the major technical areas that affect the suitability of the site. This early site suitability evaluation (ESSE) was conducted by a team of technical personnel at the request of the Associate Director of the US Department of Energy (DOE) Office of Geologic Disposal, a unit within the DOE`s Office of Civilian Radioactive Waste Management. The Yucca Mountain site has been the subject of such evaluations for over a decade. In 1983, the site was evaluated as part of a screening process to identify potentially acceptable sites. The site was evaluated in greater detail and found suitable for site characterization as part of the Environmental Assessment (EA) (DOE, 1986) required by the Nuclear Waste Policy Act of 1982 (NWPA). Additional site data were compiled during the preparation of the Site Characterization Plan (SCP) (DOE, 1988a). This early site suitability evaluation has considered information that was used in preparing both-documents, along with recent information obtained since the EA and SCP were published. This body of information is referred to in this report as ``current information`` or ``available evidence.``

One-site versus two-site phacotrabeculectomy: a prospective randomized study

Directory of Open Access Journals (Sweden)

Moschos MM

2015-08-01

Full Text Available Marilita M Moschos,1 Irini P Chatziralli,2 Michael Tsatsos3 1First Department of Ophthalmology, University of Athens, 2Second Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece; 3Department of Ophthalmology, Cambridge University Hospital NHS, Cambridge, UK Purpose: The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation.Methods: Thirty-four patients (41 eyes with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes or a two-site (19 eyes combined procedure. One-site approach consisted of a standard superior phacotrabeculectomy with a limbus-based conjunctival flap, while two-site approach consisted of a clear cornea phacoemulsification and a separate superior trabeculectomy with a limbus-based conjunctival flap.Results: Mean follow-up period was 54 months (standard deviation [SD] 2.3. Mean preoperative intraocular pressure (IOP in the one-site group was 21.3 mmHg (SD 2.8 and in the two-site group was 21.8 mmHg (SD 3.0 (P>0.1. Mean postoperative IOP significantly decreased in both groups compared to the preoperative level and was 15.6 mmHg (SD 3.5 in the one-site group and 14.9 mmHg (SD 2.7 in the two-site group. Three months later, the difference between the two groups was not statistically significant (P=0.058. The one-site group required significantly more medications than the two-site group (P=0.03. Best-corrected visual acuity (BCVA improved similarly in both groups, but there was less postoperative (induced astigmatism in the two-site group in a marginal statistical level (P=0.058. Intra- and postoperative complications were comparable in the two groups.Conclusion: Both techniques yielded similar results concerning final BCVA and IOP reduction. However, the two-site group had less induced astigmatism and a better postoperative IOP control with less required

An early career in the military: A developmental-contextual perspective

Directory of Open Access Journals (Sweden)

M. E. Kotze

1999-06-01

Full Text Available Young professional military officers' experience of their internal career development was studied longitudinally from a life-span, life-space approach. Significant transitions between the life roles of worker, student and leisurite, with concomitant changes in their value system, away from traditional military values towards occupationalism, were confirmed. Gender differences were found for the work and community roles as well as in the developmental patterns of the need for authority, creativity, cultural identity, physical activities, social relationships and variety. Significant differences between the career development profiles of military and civilian students with regard to life roles were revealed. Opsomming Jong militere beroepsoffisiere se belewenis van hulle interne loopbaanontwikkeling is longitudinaal uit 'n lewenspan-Iewensruimte benadering bestudeer. Beduidende oorgange tussen die werk-, studie- en ontspanningsrolle met gepaardgaande veranderinge in hulle waardestelsel, weg van tradisionele militere waardes in die rigting van 'n beroepsgeoriënteerde waardestelsel, is bevestig. Geslagsverskille is gevind wat betref die werk- en gemeenskapsrolle sowel as in die volgende ontwikkelingspatrone: 'n behoefte aan outoriteit, kreatiwiteit, kulturele identiteit, fisiese aktiwiteite, sosiale verhoudings en verskeidenheid. Beduidende verskille met betrekking tot lewensrolle het in die loopbaanontwikkelingsprofiele van militere en burgerlike studente aan die lig gekom.

Remediation management of complex sites using an adaptive site management approach.

Science.gov (United States)

Price, John; Spreng, Carl; Hawley, Elisabeth L; Deeb, Rula

2017-12-15

Complex sites require a disproportionate amount of resources for environmental remediation and long timeframes to achieve remediation objectives, due to their complex geologic conditions, hydrogeologic conditions, geochemical conditions, contaminant-related conditions, large scale of contamination, and/or non-technical challenges. A recent team of state and federal environmental regulators, federal agency representatives, industry experts, community stakeholders, and academia worked together as an Interstate Technology & Regulatory Council (ITRC) team to compile resources and create new guidance on the remediation management of complex sites. This article summarizes the ITRC team's recommended process for addressing complex sites through an adaptive site management approach. The team provided guidance for site managers and other stakeholders to evaluate site complexities and determine site remediation potential, i.e., whether an adaptive site management approach is warranted. Adaptive site management was described as a comprehensive, flexible approach to iteratively evaluate and adjust the remedial strategy in response to remedy performance. Key aspects of adaptive site management were described, including tools for revising and updating the conceptual site model (CSM), the importance of setting interim objectives to define short-term milestones on the journey to achieving site objectives, establishing a performance model and metrics to evaluate progress towards meeting interim objectives, and comparing actual with predicted progress during scheduled periodic evaluations, and establishing decision criteria for when and how to adapt/modify/revise the remedial strategy in response to remedy performance. Key findings will be published in an ITRC Technical and Regulatory guidance document in 2017 and free training webinars will be conducted. More information is available at www.itrc-web.org. Copyright © 2017 Elsevier Ltd. All rights reserved.

Nuclear installations sites safety

International Nuclear Information System (INIS)

Barber, P.; Candes, P.; Duclos, P.; Doumenc, A.; Faure, J.; Hugon, J.; Mohammadioun, B.

1988-11-01

This report is divided into ten parts bearing: 1 Safety analysis procedures for Basis Nuclear Installations sites (BNI) in France 2 Site safety for BNI in France 3 Industrial and transport activities risks for BNI in France 4 Demographic characteristics near BNI sites in France 5 Meteorologic characteristics of BNI sites in France 6 Geological aspects near the BNI sites in France 7 Seismic studies for BNI sites in France 8 Hydrogeological aspects near BNI sites in France 9 Hydrological aspects near BNI sites in France 10 Ecological and radioecological studies of BNI sites in France [fr

Site locality identification study: Hanford Site. Volume II. Data cataloging

International Nuclear Information System (INIS)

1980-07-01

Data compilation and cataloging for the candidate site locality identification study were conducted in order to provide a retrievable data cataloging system for the present siting study and future site evaluation and licensng processes. This task occurred concurrently with and also independently of other tasks of the candidate site locality identification study. Work in this task provided the data utilized primarily in the development and application of screening and ranking processes to identify candidate site localities on the Hanford Site. The overall approach included two steps: (1) data acquisition and screening; and (2) data compilation and cataloging. Data acquisition and screening formed the basis for preliminary review of data sources with respect to their probable utilization in the candidate site locality identification study and review with respect to the level of completeness and detail of the data. The important working assumption was that the data to be used in the study be based on existing and available published and unpublished literature. The data compilation and cataloging provided the basic product of the Task; a retrievable data cataloging system in the form of an annotated reference list and key word index and an index of compiled data. The annotated reference list and key word index are cross referenced and can be used to trace and retrieve the data sources utilized in the candidate site locality identification study

Validation of Autoclave Protocols for Successful Decontamination of Category A Medical Waste Generated from Care of Patients with Serious Communicable Diseases.

Science.gov (United States)

Garibaldi, Brian T; Reimers, Mallory; Ernst, Neysa; Bova, Gregory; Nowakowski, Elaine; Bukowski, James; Ellis, Brandon C; Smith, Chris; Sauer, Lauren; Dionne, Kim; Carroll, Karen C; Maragakis, Lisa L; Parrish, Nicole M

2017-02-01

In response to the Ebola outbreak in 2014, many hospitals designated specific areas to care for patients with Ebola and other highly infectious diseases. The safe handling of category A infectious substances is a unique challenge in this environment. One solution is on-site waste treatment with a steam sterilizer or autoclave. The Johns Hopkins Hospital (JHH) installed two pass-through autoclaves in its biocontainment unit (BCU). The JHH BCU and The Johns Hopkins biosafety level 3 (BSL-3) clinical microbiology laboratory designed and validated waste-handling protocols with simulated patient trash to ensure adequate sterilization. The results of the validation process revealed that autoclave factory default settings are potentially ineffective for certain types of medical waste and highlighted the critical role of waste packaging in successful sterilization. The lessons learned from the JHH validation process can inform the design of waste management protocols to ensure effective treatment of highly infectious medical waste. Copyright © 2017 American Society for Microbiology.

Besondere körperliche Merkmale

Directory of Open Access Journals (Sweden)

Miloš Vec

2003-01-01

Full Text Available Rezensierte Werke:Simon A. Cole, Suspect Identities. A History of Fingerprinting and Criminal Identification, 2. Aufl., Cambridge: Harvard University Press 2002 (erste Aufl. ebenda 2001, 400 S., ISBN 0-674-00455-8; Documenting Individual Identity. The Development of State Practices in the Modern World, hg. von Jane Caplan, John Torpey, Princeton University Press 2001, VII, 415 S., ISBN 0-691-00911-2

Official announcement concerning the conclusion of an agreement between the Federal Republic of Germany and utilities of the electric power industry for implementing the EC transboundary guideline of October 29, 1990

International Nuclear Information System (INIS)

1991-01-01

The Federal Republic of Germany, Badenwerk AG, Bayernwerk AG, Berliner Kraft- und Licht-AG, Energie-Versorgung Schwaben AG, Hamburgische Electricitaets-Werke AG, Preussen Elektra AG, RWE Energie AG and Vereinigte Elektrizitaetswerke Westfalen AG have concluded an agreement on 7 October 1991 in order to implement the EC Council's guideline of 29 October 1990 concerning transboundary transmission of electric power via large-scale power grids. (orig./HP) [de

Deutsche Literatur von Frauen – Jetzt auch digital!

Directory of Open Access Journals (Sweden)

Corinna Heipcke

2002-07-01

Full Text Available Die Digitale Bibliothek hat eine CD-Rom ediert, auf der ein Querschnitt durch die Werke von Autorinnen aus vier Jahrhunderten enthalten ist. Die Volltexte sind integriert in ein Bearbeitungsprogramm, das quellentreues Zitieren und Volltextrecherchen ermöglicht. Damit ist ein ausgesprochen praktisches Hilfsmittel für Germanistinnen und Germanisten entstanden. An ihre Grenzen gelangt die Sammlung allerdings bei der nicht unproblematischen Textauswahl.

Introdução ao Projeto de um Sistema da Filosofia da Natureza ou Sobre o Conceito da Fí­sica Especulativa e a Organização interna de um Sistema desta Ciência 1799

Directory of Open Access Journals (Sweden)

Friedrich W. J. Schelling

2011-05-01

Full Text Available Traduçáo do original alemáo: Schelling, F. W. J. "Einleitung zu dem Entwurf eines Systems der Naturphilosophie oder über den Begriff der speculativen Physik und die innere Organisation eines Systems dieser Wissenschaft". In: Schelling, K. F. A. (Org.. Sämmtliche Werke. 14 Bdn. 1 Abt. I-X; 2 Abt. I-IV, Stuttgart/Augsburg: Cota, 1856-1861.

Wilhelm Wundts Nachlass. Eine Übersicht.

OpenAIRE

Fahrenberg, Jochen

2016-01-01

Wilhelm Wundts Publikationen bilden wahrscheinlich das umfangreichste, zweifellos aber das vielseitigste Werk eines Psychologen. Auch sein wissenschaftlicher Nachlass an Manuskripten, Exzerpten und Korrespondenz hat einen ungewöhnlichen Umfang. Während es an guten Digitalisaten seiner Publikationen noch mangelt, ist der allergrößte Teil des Wundt-Nachlasses seit Ende 2015 dokumentiert und digitalisiert (Meyer, 2015). Die Übersicht hat 12 Abschnitte: (1) Wundts Publikationen, Bibliographie...

„Ohne Anfang, ohne Ende, ohne Mitte“ – Gedanken zum Verhältnis von Sprache und Musik in Hans Zenders Shir hashirim

Directory of Open Access Journals (Sweden)

Peter Revers

2006-12-01

Full Text Available Hans Zenders abendfüllendes Werk Shir hashirim lässt sich als ein Komplex mehrerer, außerordentlich differenzierter Lesarten des Hoheliedes interpretieren. Dabei bilden textliche und musikalische Kohärenz (im Sinne syntaktischer und intertextueller Bezugsfelder eine ebenso wichtige Rolle wie deren Sprengung durch die Aufsplitterung von Worten und Textteilen und die Exponierung von primär klanglicher und lautsprachlicher Sonanz.

Site locality identification study: Hanford Site. Volume I. Methodology, guidelines, and screening

International Nuclear Information System (INIS)

1980-07-01

Presented in this report are the results of the site locality identification study for the Hanford Site using a screening process. To enable evaluation of the entire Hanford Site, the screening process was applied to a somewhat larger area; i.e., the Pasco Basin. The study consisted of a series of screening steps that progressively focused on smaller areas which are within the Hanford Site and which had a higher potential for containing suitable repository sites for nuclear waste than the areas not included for further study. Five site localities, designated H-1, H-2, H-3, H-4, H-5 (Figure A), varying in size from approximately 10 to 50 square miles, were identified on the Hanford Site. It is anticipated that each site locality may contain one or more candidate sites suitable for a nuclear waste repository. The site locality identification study began with definition of objectives and the development of guidelines for screening. Three objectives were defined: (1) maximize public health and safety; (2) minimize adverse environmental and socioeconomic impacts; and (3) minimize system costs. The screening guidelines have numerical values that provided the basis for the successive reduction of the area under study and to focus on smaller areas that had a higher likelihood of containing suitable sites

Liming in the sugarcane burnt system and the green harvest practice affect soil bacterial community in northeastern São Paulo, Brazil.

Science.gov (United States)

Val-Moraes, Silvana Pompeia; de Macedo, Helena Suleiman; Kishi, Luciano Takeshi; Pereira, Rodrigo Matheus; Navarrete, Acacio Aparecido; Mendes, Lucas William; de Figueiredo, Eduardo Barretto; La Scala, Newton; Tsai, Siu Mui; de Macedo Lemos, Eliana Gertrudes; Alves, Lúcia Maria Carareto

2016-12-01

Here we show that both liming the burnt sugarcane and the green harvest practice alter bacterial community structure, diversity and composition in sugarcane fields in northeastern São Paulo state, Brazil. Terminal restriction fragment length polymorphism fingerprinting and 16S rRNA gene cloning and sequencing were used to analyze changes in soil bacterial communities. The field experiment consisted of sugarcane-cultivated soils under different regimes: green sugarcane (GS), burnt sugarcane (BS), BS in soil amended with lime applied to increase soil pH (BSL), and native forest (NF) as control soil. The bacterial community structures revealed disparate patterns in sugarcane-cultivated soils and forest soil (R = 0.786, P = 0.002), and overlapping patterns were shown for the bacterial community structure among the different management regimes applied to sugarcane (R = 0.194, P = 0.002). The numbers of operational taxonomic units (OTUs) found in the libraries were 117, 185, 173 and 166 for NF, BS, BSL and GS, respectively. Sugarcane-cultivated soils revealed higher bacterial diversity than NF soil, with BS soil accounting for a higher richness of unique OTUs (101 unique OTUs) than NF soil (23 unique OTUs). Cluster analysis based on OTUs revealed similar bacterial communities in NF and GS soils, while the bacterial community from BS soil was most distinct from the others. Acidobacteria and Alphaproteobacteria were the most abundant bacterial phyla across the different soils with Acidobacteria Gp1 accounting for a higher abundance in NF and GS soils than burnt sugarcane-cultivated soils (BS and BSL). In turn, Acidobacteria Gp4 abundance was higher in BS soils than in other soils. These differential responses in soil bacterial community structure, diversity and composition can be associated with the agricultural management, mainly liming practices, and harvest methods in the sugarcane-cultivated soils, and they can be detected shortly after harvest.

A small animal peripheral challenge model of yellow fever using interferon-receptor deficient mice and the 17D-204 vaccine strain.

Science.gov (United States)

Thibodeaux, Brett A; Garbino, Nina C; Liss, Nathan M; Piper, Joseph; Blair, Carol D; Roehrig, John T

2012-05-02

Yellow fever virus (YFV), a member of the genus Flavivirus, is a mosquito-borne pathogen that requires wild-type (wt), virulent strains to be handled at biosafety level (BSL) 3, with HEPA-filtration of room air exhaust (BSL3+). YFV is found in tropical regions of Africa and South America and causes severe hepatic disease and death in humans. Despite the availability of effective vaccines (17D-204 or 17DD), YFV is still responsible for an estimated 200,000 cases of illness and 30,000 deaths annually. Besides vaccination, there are no other prophylactic or therapeutic strategies approved for use in human YF. Current small animal models of YF require either intra-cranial inoculation of YF vaccine to establish infection, or use of wt strains (e.g., Asibi) in order to achieve pathology. We have developed and characterized a BSL2, adult mouse peripheral challenge model for YFV infection in mice lacking receptors for interferons α, β, and γ (strain AG129). Intraperitoneal challenge of AG129 mice with 17D-204 is a uniformly lethal in a dose-dependent manner, and 17D-204-infected AG129 mice exhibit high viral titers in both brain and liver suggesting this infection is both neurotropic and viscerotropic. Furthermore the use of a mouse model permitted the construction of a 59-biomarker multi-analyte profile (MAP) using samples of brain, liver, and serum taken at multiple time points over the course of infection. This MAP serves as a baseline for evaluating novel therapeutics and their effect on disease progression. Changes (4-fold or greater) in serum and tissue levels of pro- and anti-inflammatory mediators as well as other factors associated with tissue damage were noted in AG129 mice infected with 17D-204 as compared to mock-infected control animals. Published by Elsevier Ltd.

Developmental and genetic components explain enhanced pulmonary volumes of female Peruvian Quechua.

Science.gov (United States)

Kiyamu, Melisa; Bigham, Abigail; Parra, Esteban; León-Velarde, Fabiola; Rivera-Chira, María; Brutsaert, Tom D

2012-08-01

High altitude natives have enlarged vital capacities and residual volumes (RV). Because pulmonary volumes are an indication of functionally relevant traits, such as diffusion capacity, the understanding of the factors (genetic/developmental) that influence lung volumes provides insight into the adaptive responses of highlanders. In order to test for the effect of growth and development at high altitude on lung volumes, we obtained forced vital capacities (FVC), RV, and total lung capacities (TLC) for a sample of 65 Peruvian females of mostly Quechua origins (18-34 years) who were sub-divided into two well-matched groups: 1) sea-level born and raised females (BSL, n = 34) from Lima, Peru (150 m), and 2) high-altitude born and raised females (BHA, n = 31) from Cerro de Pasco, Peru (4,338 m). To determine Quechua origins, Native American ancestry proportion (NAAP) for each individual was assessed using a panel of 70 ancestry informative markers. NAAP was similar between groups (BSL = 91.71%; BHA = 89.93%; P = 0.240), and the analysis confirmed predominantly Quechua origins. After adjusting for body size and NAAP, BHA females had significantly higher FVC (3.79 ± 0.06 l; P < 0.001), RV (0.98 ± 0.03 l; P < 0.001) and TLC (4.80 ± 0.07 l; P < 0.001) compared to BSL females (FVC = 3.33 ± 0.05 l; RV = 0.69 ± 0.03 l; TLC = 4.02 ± 0.06 l). NAAP was not associated with FVC (P = 0.352) or TLC (P = 0.506). However, NAAP was positively associated with RV (P = 0.004). In summary, results indicate that developmental exposure to high altitude in females constitutes an important factor for all lung volumes, whereas both genetic and developmental factors seem to be important for RV. Copyright © 2012 Wiley Periodicals, Inc.

The homeostatic and circadian sleep recovery responses after total sleep deprivation in mice.

Science.gov (United States)

Dispersyn, Garance; Sauvet, Fabien; Gomez-Merino, Danielle; Ciret, Sylvain; Drogou, Catherine; Leger, Damien; Gallopin, Thierry; Chennaoui, Mounir

2017-10-01

Many studies on sleep deprivation effects lack data regarding the recovery period. We investigated the 2-day homeostatic and circadian sleep recovery response to 24 h of total sleep deprivation (TSD) induced by brief rotation of an activity wheel. Eight mice were implanted with telemetry transmitters (DSI F40-EET) that recorded simultaneously their electroencephalography (EEG), locomotor activity and temperature during 24 h of baseline (BSL), TSD and 2 days of recovery (D1 and D2). In a second experiment, two groups of five non-implanted mice underwent TSD or ad libitum sleep, after which they were killed, adrenal glands were weighed and blood was collected for analysis of corticosterone concentration. During TSD mice were awake at least 97% of the time, with a consecutive sleep rebound during D1 that persisted during D2. This was characterized by increases of non-rapid eye movement (NREM) sleep (44.2 ± 6.9% for D1 and 43.0 ± 7.7% for D2 versus 33.8 ± 9.2% for BSL) and the relative delta band power (179.2 ± 34.4% for D1 and 81.9 ± 11.2% for D2). Greater NREM and REM sleep amounts were observed during the 'light' periods. Temperature and locomotor activity characteristics were unchanged during D1 and D2 versus BSL. In non-implanted mice, corticosterone levels as well as adrenal gland and overall body weights did not differ between TSD and ad libitum sleep groups. In conclusion, 24 h of TSD in an activity wheel without stress responses influence homeostatic sleep regulation with no effect on the circadian regulation over at least 2 days of recovery in mice. © 2017 European Sleep Research Society.

Scientific results from the deepened Lopra-1 borehole, Faroe Islands: Palaeomagnetic results from the Lopra-1/1A re-entry well, Faroe Islands

Directory of Open Access Journals (Sweden)

Abrahamsen, Niels

2006-07-01

Full Text Available The palaeomagnetic dating and evolution of the Faroe Islands are discussed in the context of new density and rock magnetic results from the deepened Lopra-1/1A well. The reversal chronology of thec. 6½ km thick basalt succession is also described. The polarity record of the Faroe Islands may now be correlated in detail with the Geomagnetic Polarity Time Scale. The lowermost (hidden part of thelower basalt formation correlates with Chron C26r (Selandian age, the top (exposed part of the lower basalt formation correlates with Chrons C26n, C25r and C25n (Selandian and Thanetian ageand the middle and upper basalt formations correlate with Chron C24n.3r (Ypresian. Inclinations indicate a far-sided position of the palaeomagnetic poles, which is characteristic of results from mostPalaeogene volcanics from the northern North Atlantic region. The density, magnetic susceptibility and magnetic remanence of 20 specimens from one solid core (1½ m in length and 26 sidewall cores from the well between –2219 and –3531 m below sea level (b.s.l. suggest that the volcanic materials can be divided into two characteristic groups: solid unaltered basalts and altered basalts and tuffs. The magnetic properties are typically log-normally distributed and the carriers of remanence are Ti-poor Ti-magnetites with Curie temperatures close to 580°C. The inclination of the 1½ m core at 2380 m b.s.l. is dominantly negative (two plugs at the very top of the core do show normal polarity, but they are likely to be misoriented as all specimens appear to be from one flow. Magnetic logging (magnetic susceptibility and field intensity down to 3515 m b.s.l. was made in Lopra-1/1A together with other geophysical logs but did not yield conclusive inclination data.

Development and characterization of a Rift Valley fever virus cell-cell fusion assay using alphavirus replicon vectors

International Nuclear Information System (INIS)

Filone, Claire Marie; Heise, Mark; Doms, Robert W.; Bertolotti-Ciarlet, Andrea

2006-01-01

Rift Valley fever virus (RVFV), a member of the Phlebovirus genus in the Bunyaviridae family, is transmitted by mosquitoes and infects both humans and domestic animals, particularly cattle and sheep. Since primary RVFV strains must be handled in BSL-3+ or BSL-4 facilities, a RVFV cell-cell fusion assay will facilitate the investigation of RVFV glycoprotein function under BSL-2 conditions. As for other members of the Bunyaviridae family, RVFV glycoproteins are targeted to the Golgi, where the virus buds, and are not efficiently delivered to the cell surface. However, overexpression of RVFV glycoproteins using an alphavirus replicon vector resulted in the expression of the glycoproteins on the surface of multiple cell types. Brief treatment of RVFV glycoprotein expressing cells with mildly acidic media (pH 6.2 and below) resulted in rapid and efficient syncytia formation, which we quantified by β-galactosidase α-complementation. Fusion was observed with several cell types, suggesting that the receptor(s) for RVFV is widely expressed or that this acid-dependent virus does not require a specific receptor to mediate cell-cell fusion. Fusion occurred over a broad temperature range, as expected for a virus with both mosquito and mammalian hosts. In contrast to cell fusion mediated by the VSV-G glycoprotein, RVFV glycoprotein-dependent cell fusion could be prevented by treating target cells with trypsin, indicating that one or more proteins (or protein-associated carbohydrate) on the host cell surface are needed to support membrane fusion. The cell-cell fusion assay reported here will make it possible to study the membrane fusion activity of RVFV glycoproteins in a high-throughput format and to screen small molecule inhibitors for the ability to block virus-specific membrane fusion

Adaptation of a Vocabulary Test from British Sign Language to American Sign Language

Science.gov (United States)

Mann, Wolfgang; Roy, Penny; Morgan, Gary

2016-01-01

This study describes the adaptation process of a vocabulary knowledge test for British Sign Language (BSL) into American Sign Language (ASL) and presents results from the first round of pilot testing with 20 deaf native ASL signers. The web-based test assesses the strength of deaf children's vocabulary knowledge by means of different mappings of…

Site Features

Data.gov (United States)

U.S. Environmental Protection Agency — This dataset consists of various site features from multiple Superfund sites in U.S. EPA Region 8. These data were acquired from multiple sources at different times...

Nevada Test Site Environmental Report 2007 Attachment A: Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy Wills

2008-09-01

This appendix expands on the general description of the Nevada Test Site (NTS) presented in the Introduction to the Nevada Test Site Environmental Report 2007 (U.S. Department of Energy [DOE], 2008). Included are subsections that summarize the site's geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site which afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Hanford Site Development Plan

International Nuclear Information System (INIS)

Rinne, C.A.; Curry, R.H.; Hagan, J.W.; Seiler, S.W.; Sommer, D.J.; Yancey, E.F.

1990-01-01

The Hanford Site Development Plan (Site Development Plan) is intended to guide the short- and long-range development and use of the Hanford Site. All acquisition, development, and permanent facility use at the Hanford Site will conform to the approved plan. The Site Development Plan also serves as the base document for all subsequent studies that involve use of facilities at the Site. This revision is an update of a previous plan. The executive summary presents the highlights of the five major topics covered in the Site Development Plan: general site information, existing conditions, planning analysis, Master Plan, and Five-Year Plan. 56 refs., 67 figs., 31 tabs

Hanford Site Development Plan

Energy Technology Data Exchange (ETDEWEB)

Rinne, C.A.; Curry, R.H.; Hagan, J.W.; Seiler, S.W.; Sommer, D.J. (Westinghouse Hanford Co., Richland, WA (USA)); Yancey, E.F. (Pacific Northwest Lab., Richland, WA (USA))

1990-01-01

The Hanford Site Development Plan (Site Development Plan) is intended to guide the short- and long-range development and use of the Hanford Site. All acquisition, development, and permanent facility use at the Hanford Site will conform to the approved plan. The Site Development Plan also serves as the base document for all subsequent studies that involve use of facilities at the Site. This revision is an update of a previous plan. The executive summary presents the highlights of the five major topics covered in the Site Development Plan: general site information, existing conditions, planning analysis, Master Plan, and Five-Year Plan. 56 refs., 67 figs., 31 tabs.

TL/OSL properties of natural schist for archaeological dating and retrospective dosimetry

International Nuclear Information System (INIS)

Afouxenidis, D.; Stefanaki, E.C.; Polymeris, G.S.; Sakalis, A.; Tsirliganis, N.C.; Kitis, G.

2007-01-01

Schist, a metamorphic rock composed largely of quartz and muscovite, has been used as a building stone through the centuries in many parts of the world. In ancient Greece, it was used in buildings and monuments (Knossos, Karthaia, etc). Basic TL and OSL properties of schist are studied in the present work to evaluate its potential use in archaeological dating and retrospective dosimetry. In particular, the optical stability, as well as the linearity of the TL and OSL signal were investigated for samples of natural schist obtained from a roofing slate. The results indicate that both signals are rapidly bleached when the sample is exposed to sunlight. An exposure of 1 min reduces the TL signal by 93%, the IRSL signal by 99% and the post-IR BSL signal by 90%. The dose response was found to be linear for a radiation dose at least up to 75 Gy for the TL and the IR OSL signal and at least up to 25 Gy for the post-IR BSL signal

Technical summary of groundwater quality protection program at the Savannah River Site, 1952--1986. Volume 1, Site geohydrology and waste sites

Energy Technology Data Exchange (ETDEWEB)

Heffner, J.D. [ed.] [Exploration Resources, Inc., Athens, GA (United States)

1991-11-01

This report provides information regarding the status of and groundwater quality at the waste sites at the Department of Energy`s (DOE) Savannah River Site (SRS). Specific information provided for each waste site at SRS includes its location, size, inventory (when known), and history. Many waste sites at SRS are considered to be of little environmental concern because they contain nontoxic or inert material such as construction rubble and debris. Other waste sites, however, either are known to have had an effect on groundwater quality or are suspected of having the potential to affect groundwater. Monitoring wells have been installed at most of these sites; monitoring wells are scheduled for installation at the remaining sites. Results of the groundwater analyses from these monitoring wells, presented in the appendices, are used in the report to help identify potential contaminants of concern, if any, at each waste site. The list of actions proposed for each waste site in Christensen and Gordon`s 1983 report are summarized, and an update is provided for each site. Planned actions for the future are also outlined.

New Reactor Siting in Finland, Hanhikivi Site in Pyhaejoki - STUK preliminary safety assessment

International Nuclear Information System (INIS)

Nevalainen, Janne

2013-01-01

STUK has performed a preliminary assessment of the Decision-in-Principle on the Fennovoima application. A variety of factors must be considered in the selection of a site, including effects of the site on the plant design and the effects of the plant on the site environment. These include external hazards, both natural and human-induced. Since this is a new site, an extensive siting process is followed, that can include an EIA. A site survey is performed to identify candidate sites, after investigating a large region and rejecting unsuitable sites. The remaining sites are then screened and compared on the basis of safety and other considerations to select one or more preferred sites. Natural hazards include geology, seismology, hydrology and meteorology. Offshore ice will be a particular hazard for this plant, since the site is on average only 1.5 m above sea level. The design basis earthquake corresponds to a return frequency of 100,000 years, with 50 % confidence. The existing sites in southern Finland used a design peak ground acceleration of 0.1 g with the ground response spectrum maximum at 10 Hz. The candidate sites in northern Finland will require a peak ground acceleration of 0.2 g with the ground response spectrum maximum at 25 Hz

Hydrogeological Site Descriptive Model - a strategy for its development during Site Investigations

Energy Technology Data Exchange (ETDEWEB)

Rhen, Ingvar [SWECO VIAK AB, Goeteborg (Sweden); Follin, Sven [SF GeoLogic AB, Stockholm (Sweden); Hermanson, Jan [Golder Associates, Stockholm (Sweden)

2003-04-01

The report is to present a strategy for the development of the Site Descriptive Hydrogeological Model within the SKB Site Investigation Programme. The report, and similar reports from the Geology, Rock Mechanics, Thermal properties, Hydrogeochemistry, Transport Properties and Surface Ecosystem disciplines are intended to guide SKB Site Descriptive Modelling but also to provide the authorities with an overview of how the modelling should be performed. Thus the objectives of this report are to: provide guidelines for the modelling of different sites resulting in consistent handling of modelling issues during the Site Investigations, provide a structure for the modelling sequence that is suitable for the establishment of a Site Descriptive model and provide some necessary details that should be considered in a Site Descriptive model.

Hydrogeological Site Descriptive Model - a strategy for its development during Site Investigations

International Nuclear Information System (INIS)

Rhen, Ingvar; Follin, Sven; Hermanson, Jan

2003-04-01

The report is to present a strategy for the development of the Site Descriptive Hydrogeological Model within the SKB Site Investigation Programme. The report, and similar reports from the Geology, Rock Mechanics, Thermal properties, Hydrogeochemistry, Transport Properties and Surface Ecosystem disciplines are intended to guide SKB Site Descriptive Modelling but also to provide the authorities with an overview of how the modelling should be performed. Thus the objectives of this report are to: provide guidelines for the modelling of different sites resulting in consistent handling of modelling issues during the Site Investigations, provide a structure for the modelling sequence that is suitable for the establishment of a Site Descriptive model and provide some necessary details that should be considered in a Site Descriptive model

Computer aided site management. Site use management by digital mapping

International Nuclear Information System (INIS)

Chupin, J.C.

1990-01-01

The logistics program developed for assisting the Hague site management is presented. A digital site mapping representation and geographical data bases are used. The digital site map and its integration into a data base are described. The program can be applied to urban and rural land management aid. Technical administrative and economic evaluations of the program are summarized [fr

Site characterization quality assurance for the California LLRW Disposal Site Project

International Nuclear Information System (INIS)

Hanrahan, T.P.; Ench, J.E.; Serlin, C.L.; Bennett, C.B.

1988-01-01

In December of 1985 US Ecology was chosen as the license designee for the State of California's low-level radioactive waste disposal facility. In early 1987, three candidate sites were selected for characterization studies in preparation for identifying the preferred site. The geotechnical characterization activities along with studies of the ecological and archaeological attributes, as well as assessments of the socio-economic impacts and cultural resources all provide input towards selection of the proposed site. These technical studies in conjunction with comments from local citizen committees and other interested parties are used as a basis for determining the proposed site for which full site characterization as required by California licensing requirements are undertaken. The purpose of this paper is to present an overview of the program for Quality Assurance and Quality Control for the site characterization activities on the California LLRW Disposal Site Project. The focus is on three major perspectives: The composite QA Program and two of the primary characterization activities, the geotechnical and the meteorological investigations

Site selection

International Nuclear Information System (INIS)

Olsen, C.W.

1983-07-01

The conditions and criteria for selecting a site for a nuclear weapons test at the Nevada Test Site are summarized. Factors considered are: (1) scheduling of drill rigs, (2) scheduling of site preparation (dirt work, auger hole, surface casing, cementing), (3) schedule of event (when are drill hole data needed), (4) depth range of proposed W.P., (5) geologic structure (faults, Pz contact, etc.), (6) stratigraphy (alluvium, location of Grouse Canyon Tuff, etc.), (7) material properties (particularly montmorillonite and CO 2 content), (8) water table depth, (9) potential drilling problems (caving), (10) adjacent collapse craters and chimneys, (11) adjacent expended but uncollapsed sites, (12) adjacent post-shot or other small diameter holes, (13) adjacent stockpile emplacement holes, (14) adjacent planned events (including LANL), (15) projected needs of Test Program for various DOB's and operational separations, and (16) optimal use of NTS real estate

Site-Specific Atmospheric Dispersion Characteristics of Korean Nuclear Power Plant Sites

International Nuclear Information System (INIS)

Han, M. H.; Kim, E. H.; Suh, K. S.; Hwang, W. T.; Choi, Y. G.

2001-01-01

Site-specific atmospheric dispersion characteristics have been analyzed. The northwest and the southwest wind prevail on nuclear sites of Korea. The annual isobaric surface averaged for twenty years around Korean peninsula shows that west wind prevails. The prevailing west wind is profitable in the viewpoint of radiation protection because three of four nuclear sites are located in the east side. Large scale field tracer experiments over nuclear sites have been conducted for the purpose of analyzing the atmospheric dispersion characteristics and validating a real-time atmospheric dispersion and dose assessment system FADAS. To analyze the site-specific atmospheric dispersion characteristics is essential for making effective countermeasures against a nuclear emergency

29 CFR 1926.752 - Site layout, site-specific erection plan and construction sequence.

Science.gov (United States)

2010-07-01

... 29 Labor 8 2010-07-01 2010-07-01 false Site layout, site-specific erection plan and construction... Steel Erection § 1926.752 Site layout, site-specific erection plan and construction sequence. (a... strength or sufficient strength to support the loads imposed during steel erection. (c) Site layout. The...

Biological Terrorism: US Policies to Reduce Global Biothreats

Science.gov (United States)

2008-09-01

program for pro- jects that advance BEP objectives. Global Cooperation to develop bio- safety and pathogen security stan- dards that are consistent with...security. The Organization for Economic Cooperation and Development ( OECD ) has recently developed voluntary biosecurity guidelines for implementation...Abbreviations AG Australia Group BEP Biosecurity Engagement Program BSL Biosafety level BWC Biological Weapons Convention BWC-ISU Biological Weapons

Clinical Characterization of Aerosolized Francisella tularensis Infection in Cynomolgus macaques

Science.gov (United States)

2016-11-21

All airflows, environmental monitoring, and system balancing were configured, controlled, and recorded through the institute standard automated...were used as a baseline to fit an autoregressive integrated moving average (ARIMA) model. Temperature elevations exceeding three standard deviations...supervision of a pathologist board certified by the American College of Veterinary Pathologist in a biosafety level (BSL) 3 necropsy facility. Tissues

Contaminated Sites in Iowa

Data.gov (United States)

Iowa State University GIS Support and Research Facility — Sites contaminated by hazardous materials or wastes. These sites are those administered by the Contaminated Sites Section of Iowa DNR. Many are sites which are...

Hanford Site Development Plan

International Nuclear Information System (INIS)

Hathaway, H.B.; Daly, K.S.; Rinne, C.A.; Seiler, S.W.

1993-05-01

The Hanford Site Development Plan (HSDP) provides an overview of land use, infrastructure, and facility requirements to support US Department of Energy (DOE) programs at the Hanford Site. The HSDP's primary purpose is to inform senior managers and interested parties of development activities and issues that require a commitment of resources to support the Hanford Site. The HSDP provides an existing and future land use plan for the Hanford Site. The HSDP is updated annually in accordance with DOE Order 4320.1B, Site Development Planning, to reflect the mission and overall site development process. Further details about Hanford Site development are defined in individual area development plans

Site Calibration report

DEFF Research Database (Denmark)

Yordanova, Ginka; Vesth, Allan

The report describes site calibration measurements carried out on a site in Denmark. The measurements are carried out in accordance to Ref. [1]. The site calibration is carried out before a power performance measurement on a given turbine to clarify the influence from the terrain on the ratio...

Site directed recombination

Science.gov (United States)

Jurka, Jerzy W.

1997-01-01

Enhanced homologous recombination is obtained by employing a consensus sequence which has been found to be associated with integration of repeat sequences, such as Alu and ID. The consensus sequence or sequence having a single transition mutation determines one site of a double break which allows for high efficiency of integration at the site. By introducing single or double stranded DNA having the consensus sequence flanking region joined to a sequence of interest, one can reproducibly direct integration of the sequence of interest at one or a limited number of sites. In this way, specific sites can be identified and homologous recombination achieved at the site by employing a second flanking sequence associated with a sequence proximal to the 3'-nick.

Nevada National Security Site Environmental Report 2011 Attachment A: Site Description

International Nuclear Information System (INIS)

Wills, Cathy

2012-01-01

This attachment expands on the general description of the Nevada National Security Site (NNSS) presented in the Introduction to the Nevada National Security Site Environmental Report 2011. Included are subsections that summarize the site's geological, hydrological, climatological, and ecological setting and the cultural resources of the NNSS. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NNSS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NNSS. The NNSS environment contributes to several key features of the site that afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NNSS operations. These key features include the general remote location of the NNSS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Hanford Site Infrastructure Plan

International Nuclear Information System (INIS)

1990-01-01

The Hanford Site Infrastructure Plan (HIP) has been prepared as an overview of the facilities, utilities, systems, and services that support all activities on the Hanford Site. Its purpose is three-fold: to examine in detail the existing condition of the Hanford Site's aging utility systems, transportation systems, Site services and general-purpose facilities; to evaluate the ability of these systems to meet present and forecasted Site missions; to identify maintenance and upgrade projects necessary to ensure continued safe and cost-effective support to Hanford Site programs well into the twenty-first century. The HIP is intended to be a dynamic document that will be updated accordingly as Site activities, conditions, and requirements change. 35 figs., 25 tabs

Open-field test site

Science.gov (United States)

Gyoda, Koichi; Shinozuka, Takashi

1995-06-01

An open-field test site with measurement equipment, a turn table, antenna positioners, and measurement auxiliary equipment was remodelled at the CRL north-site. This paper introduces the configuration, specifications and characteristics of this new open-field test site. Measured 3-m and 10-m site attenuations are in good agreement with theoretical values, and this means that this site is suitable for using 3-m and 10-m method EMI/EMC measurements. The site is expected to be effective for antenna measurement, antenna calibration, and studies on EMI/EMC measurement methods.

Methodology of site studies

International Nuclear Information System (INIS)

Caries, J.C.; Hugon, J.; Grauby, A.

1980-01-01

This methodology consists in an essentially dynamic, estimated and follow-up analysis of the impact of discharges on all the environment compartments, whether natural or not, that play a part in the protection of man and his environment. It applies at two levels, to wit: the choice of site, or the detailed study of the site selected. Two examples of its application will be developed, namely: at the choice of site level in the case of marine sites, and of the detailed study level of the chosen site in that of a riverside site [fr

SITE: a methodology for assessment of energy facility siting patterns. Regional studies program

International Nuclear Information System (INIS)

Frigerio, N.A.; Habegger, L.J.; King, R.F.; Hoover, L.J.; Clark, N.A.; Cobian, J.M.

1975-08-01

The timely development of the nation's energy production capacity in a manner that minimizes potential adverse local and regional impacts associated with energy facilities requires the use of sophisticated techniques for evaluation of siting alternatives and fuel cycle options. This report is a documentation of the computerized SITE methodology that has been developed for evaluating health, environmental, and socioeconomic impacts related to utilization of alternate sites for energy production within a region of interest. The cost, impact, and attribute vectors, which are generated and displayed on density maps, can be used in a multiparameter overlay process to identify preferable siting areas. The assessment of clustered facilities in energy centers is also possible within the SITE analysis framework. An application of the SITE methodology to Northern Illinois is presented. Also included is a description of the ongoing extension of SITE for the accumulative evaluation of alternative regional energy siting patterns and fuel cycle options. An appendix provides documentation and user information for the SITE computer program

Site Characterization Work Plan for Gnome-Coach Site, New Mexico

Energy Technology Data Exchange (ETDEWEB)

DOE/NV

2001-02-13

Project Gnome was the first nuclear experiment conducted under the U.S. Atomic Energy Commission (AEC), predecessor to the U.S. Department of Energy (DOE), Plowshare Program. Gnome was part of a joint government-industry experiment focused on developing nuclear devices exclusively for peaceful purposes. The intent of the Gnome experiment was to evaluate the effects of a nuclear detonation in a salt medium. Historically, Project Gnome consisted of a single detonation of a nuclear device on December 10, 1961. Since the Gnome detonation, the AEC/DOE has conducted surface restoration, site reconnaissance, and decontamination and decommissioning activities at the site. In addition, annual groundwater sampling is performed under a long-term hydrological monitoring program begun in 1980. Coach, an experiment to be located near the Gnome project, was initially scheduled for 1963. Although construction and rehabilitation were completed for Coach, the experiment was canceled and never executed. Known collectively as Project Gnome-Coach, the site is situated within the Salado Formation approximately 25 miles east of Carlsbad, New Mexico, in Eddy County, and is comprised of nearly 680 acres, of which 60 acres are disturbed from the combined AEC/DOE operations. The scope of this work plan is to document the environmental objectives and the proposed technical site investigation strategies that will be utilized for the site characterization of the project. The subsurface at the Gnome-Coach site has two contaminant sources that are fundamentally different in terms of both their stratigraphic location and release mechanism. The goal of this characterization is to collect data of sufficient quantity and quality to establish current site conditions and to use the data to identify and evaluate if further action is required to protect human health and the environment and achieve permanent closure of the site. The results of these activities will be presented in a subsequent corrective

Auhagen, Axel; Ermer, Klaus; Mohrmann, Rita (Hrsg.): Landschaftsplanung in der Praxis

OpenAIRE

Weihrich, Dietmar

2013-01-01

Die Landschaftsplanung hat den Auftrag, die Erfordernisse und Maßnahmen des Naturschutzes für den jeweiligen Planungsraum darzustellen. Sie ist seit mehr als 25 Jahren ein fester Bestandteil des Bundesnaturschutzgesetzes. In dieser Zeit erweiterte sich das fachlich-methodische Instrumentarium stark, aber es fehlte lange eine Publikation, welche die zur Verfügung stehenden Methoden übersichtlich und praxisorientiert darstellt. Das vorliegende Werk wirkt diesem Defizit entgegen.

In der Suche nach eigenem Sprachstandards

Directory of Open Access Journals (Sweden)

Lada Badurina

1992-01-01

Full Text Available Im Artikl wird dreifache Lösungsmöglichkeit des burgenländrich-kroatischen Sprachkomplexes vor-gesehen: Stützung auf den deutschen schriftsprachlichen Ausdruck, Übernahme des südlichen kroatischen Standards oder Aufbau eigener Sprachnorm. Neulich veröffentlichtes Werk Gradis6anskohrvatski-hrvatsko-nim§ki rjeönik zeugt über die Anbahnung der schwierigten aber zugleich annehmbarsten Lösung: Standardisierung der eigenen Sprache.

Erving Goffmans Kaderanalyse: een Negatie van Herbert Blumers Symbolisch Interactionisme

OpenAIRE

Verhoeven, Jef

1983-01-01

Goffmans sociologie wordt dikwijls symbolisch interactionistisch genoemd. Om dit probleem te onderzoeken werd het werk van Goffman vergeleken met de visie van Blumer over het symbolisch interactionisme. Er wordt aangetoond dat Goffmans kaderanalyse, uitgewerkt in Frame Analysis (1974), reeds in zijn vroegere werken aanwezig was en dat deze benadering een andere bedoeling heeft dan het symbolisch interactionisme. In het artikel wordt verduidelijkt dat beide auteurs vertrekken van een ged...

The Bril (De Bril)

Science.gov (United States)

2005-11-01

instructies betreffende de uitvoering en controleert de uitvoering. 3 Standaardisatie van werkprocessen. De inhoud van bet werk is beschreven ( IKEA ...R., Bolt6, B., & Jones, D. G. (2003). Designing for Situation Awareness: An Approach to User-Centered Design . London: Taylor & Francis. Endsley, M... design of work teams. In J. W. Lorsch (Ed.), Handbook of organizational behavior (pp. 315-342). Englewood Cliffs, NJ: Prentice-Hall. Harrison, M.A. (1990

Problem Definition Study on TAX (1-acetylhexahydro-3,5-dinitro-1,3,5- triazine), SEX (1-acetyloctahydro-3,5,7-trinitro-1,3,5,7-tetrazocine), Lead Salicylate and Lead Beta-Resorcylate 2-Nitrodiphenylamine and Ethyl Centralite

Science.gov (United States)

1979-07-01

IV-14 IV-3. Nuclear Magnetic Resonance Spectrum of 2-Nitrodiphenylamine ................. IV-15 IV-4. Map of Radford Army Amumunition Plant...Chemie GmbH Chemische Werke Munchen Otto Barlocher CmbH Metallgesellschaft AG ITALY Stabilital SpA SPAIN Industrias Quimicas de Parets. SA UNITED KINGDOM...abnormal cristae and matrix, and disrupted nuclear membrane. The mitochrondria seemed to be the organelle most frequently affected. Thus, it was shown that

Ongelijk leven, ongelijk sterven

OpenAIRE

Lecq, Fieke

2001-01-01

textabstractOverlappende generaties-modellen zijn een prachtig instrument voor economen, omdat ze via inzichtelijke mechanismen interessante uitkomsten opleveren. In deze modellen worden meerdere generaties gemodelleerd, die elk een voorraad geld of goederen bij geboorte meekrijgen, deze hoeveelheid tijdens hun leven veranderen door inkomen uit werk en uitgaven wegens consumptie en aan het eind van hun leven het restant nalaten aan de volgende generatie. Zolang mensen niet weten hoe oud ze pr...

Hanford Site Development Plan

International Nuclear Information System (INIS)

Hathaway, H.B.; Daly, K.S.; Rinne, C.A.; Seiler, S.W.

1992-05-01

The Hanford Site Development Plan (HSDP) provides an overview of land use, infrastructure, and facility requirements to support US Department of Energy (DOE) programs at the Hanford Site. The HSDP's primary purpose is to inform senior managers and interested parties of development activities and issues that require a commitment of resources to support the Hanford Site. The HSDP provides a land use plan for the Hanford Site and presents a picture of what is currently known and anticipated in accordance with DOE Order 4320.1B. Site Development Planning. The HSDP wig be updated annually as future decisions further shape the mission and overall site development process. Further details about Hanford Site development are defined in individual area development plans

The disposal of Canada's nuclear fuel waste: site screening and site evaluation technology

International Nuclear Information System (INIS)

Davison, C.C.; Brown, A.; Everitt, R.A.; Gascoyne, M.; Kozak, E.T.; Lodha, G.S.; Martin, C.D.; Soonawala, N.M.; Stevenson, D.R.; Thorne, G.A.; Whitaker, S.H.

1994-06-01

The concept for the disposal of Canada's nuclear fuel waste is to dispose of the waste in an underground vault, nominally at 500 m to 1000 m depth, at a suitable site in plutonic rock of the Canadian Shield. The feasibility of this concept and assessments of its impact on the environment and human health, will be documented by AECL in an Environmental Impact Statement (EIS). This report is one of nine primary references for the EIS. It describes the approach and methods that would be used during the siting stage of the disposal project to identify a preferred candidate disposal site and to confirm its suitability for constructing a disposal facility. The siting stage is divided into two distinct but closely related substages, site screening and site evaluation. Site screening would mainly involve reconnaissance investigations of siting regions of the Shield to identify potential candidate areas where suitable vault locations are likely to exist. Site screening would identify a small number of candidate areas where further detailed investigations were warranted. Site evaluation would involve progressively more detailed surface and subsurface investigations of the candidate areas to first identify potentially suitable vault locations within the candidate areas, and then characterize these potential disposal sites to identify the preferred candidate location for constructing the disposal vault. Site evaluation would conclude with the construction of exploratory shafts and tunnels at the preferred vault location, and underground characterization would be done to confirm the suitability of the preferred candidate site. An integrated program of geological, geophysical, hydrogeological, geochemical and geomechanical investigations would be implemented to obtain the geoscience information needed to assess the suitability of the candidate siting areas and candidate sites for locating a disposal vault. The candidate siting areas and candidate disposal vault sites would be

Site observational work plan for the UMTRA Project site at Spook, Wyoming

International Nuclear Information System (INIS)

1995-05-01

The Spook, Wyoming, site observational work plan proposes site-specific activities to achieve compliance with Subpart B of 40 CFR Part 192 (1994) of the final US Environmental Protection Agency (EPA) ground water protection standards 60 FR 2854 (1995) at this Uranium Mill Tailing Remedial Action (UMTRA) Project site. This draft SOWP presents a comprehensive summary of existing site characterization data, a conceptual site model of the nature and extent of ground water contamination, exposure pathways, and potential impact to human health and the environment. Section 2.0 describes the requirements for meeting ground water standards at UMTRA Project sites. Section 3.0 defines past and current conditions, describes potential environmental and human health risks, and provides site-specific data that supports the selection of a proposed ground water compliance strategy. Section 4.0 provides the justification for selecting the proposed ground water compliance strategy based on the framework defined in the ground water programmatic environmental impact statement (PEIS)

Hanford Site Composite Analysis Technical Approach Description: Hanford Site Disposition Baseline.

Energy Technology Data Exchange (ETDEWEB)

Cobb, M. A. [CH2M HILL Plateau Remediation Company, Richland, WA (United States); Dockter, R. E. [CH2M HILL Plateau Remediation Company, Richland, WA (United States)

2017-10-02

The permeability of ground surfaces within the U.S. Department of Energy’s (DOE) Hanford Site strongly influences boundary conditions when simulating the movement of groundwater using the Subsurface Transport Over Multiple Phases model. To conduct site-wide modeling of cumulative impacts to groundwater from past, current, and future waste management activities, a site-wide assessment of the permeability of surface conditions is needed. The surface condition of the vast majority of the Hanford Site has been and continues to be native soils vegetated with dryland grasses and shrubs.

Thioredoxin binding site of phosphoribulokinase overlaps the catalytic site

International Nuclear Information System (INIS)

Porter, M.A.; Hartman, F.C.

1986-01-01

The ATP-regulatory binding site of phosphoribulokinase was studied using bromoacetylethanolamine phosphate (BrAcNHEtOP). BrAcNHEtOP binds to the active-regulatory binding site of the protein. Following trypsin degradation of the labeled protein, fragments were separated by HPLC and sequenced. (DT)

Web sites that work secrets from winning web sites

CERN Document Server

Smith, Jon

2012-01-01

Leading web site entrepreneur Jon Smith has condensed the secrets of his success into 52 inspiring ideas that even the most hopeless technophobe can implement. The brilliant tips and practical advice in Web sites that work will uplift and transform any website, from the simplest to the most complicated. It deals with everything from fundamentals such as how to assess the effectiveness of a website and how to get a site listed on the most popular search engines to more sophisticated challenges like creating a community and dealing with legal requirements. Straight-talking, practical and humorou

Nevada National Security Site Environmental Report 2011 Attachment A: Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy Wills, ed.

2012-09-12

This attachment expands on the general description of the Nevada National Security Site (NNSS) presented in the Introduction to the Nevada National Security Site Environmental Report 2011. Included are subsections that summarize the site's geological, hydrological, climatological, and ecological setting and the cultural resources of the NNSS. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NNSS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NNSS. The NNSS environment contributes to several key features of the site that afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NNSS operations. These key features include the general remote location of the NNSS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

75 FR 879 - National Semiconductor Corporation Arlington Manufacturing Site Including On-Site Leased Workers...

Science.gov (United States)

2010-01-06

... engaged in activities related to the production of integrated circuits. The company reports that on-site... Corporation Arlington Manufacturing Site Including On-Site Leased Workers From GCA, CMPA (Silverleaf), Custom..., applicable to workers of National Semiconductor Corporation, Arlington Manufacturing Site, including on-site...

Die Raumdarstellung im erzählenden Werk um 1900

OpenAIRE

Lu, Xiaoli

2011-01-01

In der Literatur existiert eine eigene Welt, die mit Raum und Zeit verbunden ist. Im 19. Jahrhundert gewinnen beide, Raum und Zeit, an Bedeutung als bewusst eingesetzte Gestaltungselemente. Es bilden sich zwei Grundrichtungen heraus, eine mit dem Erzählgeschehen verknüpfte Semantisierung in der Klassik und in der Romantik und eine betonte Fixierung des Geschehens in der realen Welt durch genaue Zeit- und Ortsangaben im Realismus. Die Semantisierung von Raum und Zeit führt zu einer Bedeutungss...

Besluitvorming rondom pensioneren: de invloed van werk- en organisatiecontext

NARCIS (Netherlands)

van Solinge, H.; Henkens, C.J.I.M.

2011-01-01

This article links organizational forces to individual decision making on retirement. We examine to what extent work characteristics and organizational context (organizational policies and workplace norms toward retirement) affect the (planned) retirement age of workers aged 50 and over. We use data

Verkeersonveiligheid bij werk in uitvoering deel II : een ongevallenanalyse.

NARCIS (Netherlands)

Janssen, S.T.M.C. & Weijermars, W.A.M.

2009-01-01

This report discusses the results of the second phase of the study Road Safety at Roadworks which is carried out by SWOV, commissioned by the Information and Technology Platform for Infrastructure, Traffic, Transport and Public space CROW. It consists of an analysis of crash data from the Dutch road

Werk van de tweede soort : boerinnen in de melkveehouderij

NARCIS (Netherlands)

Rooij, de S.

1992-01-01

This study of the changing nature of farmwork for farmers' wives focuses on two central questions. The first concerns the effects on the wife's labour of scale- enlargement and specialization. Both of these processes can be considered as the accumulation of technological, economic and political

1994 Site environmental report

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-07-01

The Fernald site is a Department of Energy (DOE)-owned facility that produced high-quality uranium metals for military defense for nearly 40 years. DOE suspended production at the site in 1989 and formally ended production in 1991. Although production activities have ceased, the site continues to examine the air and liquid pathways as possible routes through which pollutants from past operations and current remedial activities may leave the site. The Site Environmental Report (SER) is prepared annually in accordance with DOE Order 5400.1, General Environmental Protection Program. This 1994 SER provides the general public as well as scientists and engineers with the results from the site`s ongoing Environmental Monitoring Program. Also included in this report is information concerning the site`s progress toward achieving full compliance with requirements set forth by DOE, U.S. Environmental Protection Agency (USEPA), and Ohio EPA (OEPA). For some readers, the highlights provided in this Executive Summary may provide sufficient information. Many readers, however, may wish to read more detailed descriptions of the information than those which are presented here. All information presented in this summary is discussed more fully in the main body of this report.

Site Specific Ground Response Analysis for Quantifying Site Amplification at A Regolith Site

Directory of Open Access Journals (Sweden)

Bambang Setiawan

2017-08-01

Full Text Available DOI: 10.17014/ijog.4.3.159-167A numerical model has demonstrated that it can simulate reasonably well earthquake motions at the ground level during a seismic event. The most widely used model is an equivalent linear approach. The equivalent linear model was used to compute the free-field response of Adelaide regolith during the 1997 Burra earthquake. The aim of this study is to quantify the amplification at the investigated site. The model computed the ground response of horizontally layered soil deposits subjected to transient and vertically propagating shear waves through a one-dimensional-soil column. Each soil layer was assumed to be homogeneous, visco-elastic, and infinite in the horizontal extent. The results of this study were compared to other studies and forward computation of the geotechnical dynamic parameters of the investigated site. The amplification triggered by the 1997 Burra seismic event was deduced. This study reveals the amplification factor up to 3.6 at the studied site.

A future for nuclear sites beyond their service life. Nuclear site value development; Un avenir pour les sites nucleaires en fin de cycle. Valorisation des sites nucleaires

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-07-01

As the nuclear industry moves into a new development phase, many facilities built in the fifties and sixties are reaching the end of their service life. Dismantling them and rehabilitating the sites on which they stand is a major industrial challenge which will give rise to a number of new projects. AREVA has more than 20 years' experience in these highly technical fields. As more and more sites reach the end of their service life, AREVA considers nuclear site value development as a fully-fledged industrial activity. The group's competencies in this field have been grouped together to form a dedicated entity: the Nuclear Site Value Development Business Unit, created in 2008. Several billion euros are invested in site value development projects which are far-reaching and complex, and often last for several decades. Long before work actually begins, lengthy studies and preparations are required to schedule operations, select the techniques to be used and optimize costs and deadlines. The Nuclear Site Value Development BU is currently working on four major projects involving its own facilities and those of the CEA: - La Hague: dismantling of the first generation of used fuel recycling facilities. Between 1966 and 1998, almost 5,000 tons of used fuel from graphite-moderated gas-cooled reactors, 4,500 tons of light water reactor fuel, as well as fuel from fast reactors and research reactors, were treated at UP2 400, the very first industrial recycling plant on the La Hague site. - Marcoule: first-time dismantling of a recycling plant. 1,000 rooms to be cleaned up, 30,000 tons of waste to be treated, 30 years of work. - Cadarache: first-time dismantling of a Mox fuel fabrication plant. The Cadarache plant was commissioned in 1962 to fabricate fuel for fast reactors; this was followed by MOX fuel for light water reactors, an activity which continued until the plant was shut down in 2003. - Annecy and Veurey: giving a new lease of life to former industrial sites

Implementing Site-based Budgeting.

Science.gov (United States)

Sielke, Catherine C.

2001-01-01

Discusses five questions that must be answered before implementing site-based budgeting: Why are we doing this? What budgeting decisions will be devolved to the school site? How do dollars flow from the central office to the site? Who will be involved at the site? How will accountability be achieved? (Author/PKP)

EPA True NO2 ground site measurements – multiple sites, TCEQ ground site measurements of meteorological and air pollution parameters – multiple sites ,GeoTASO NO2 Vertical Column

Data.gov (United States)

U.S. Environmental Protection Agency — EPA True NO2 ground site measurements – multiple sites - http://www-air.larc.nasa.gov/cgi-bin/ArcView/discover-aq.tx-2013; TCEQ ground site measurements of...

New Site Coefficients and Site Classification System Used in Recent Building Seismic Code Provisions

Science.gov (United States)

Dobry, R.; Borcherdt, R.D.; Crouse, C.B.; Idriss, I.M.; Joyner, W.B.; Martin, G.R.; Power, M.S.; Rinne, E.E.; Seed, R.B.

2000-01-01

Recent code provisions for buildings and other structures (1994 and 1997 NEHRP Provisions, 1997 UBC) have adopted new site amplification factors and a new procedure for site classification. Two amplitude-dependent site amplification factors are specified: Fa for short periods and Fv for longer periods. Previous codes included only a long period factor S and did not provide for a short period amplification factor. The new site classification system is based on definitions of five site classes in terms of a representative average shear wave velocity to a depth of 30 m (V?? s). This definition permits sites to be classified unambiguously. When the shear wave velocity is not available, other soil properties such as standard penetration resistance or undrained shear strength can be used. The new site classes denoted by letters A - E, replace site classes in previous codes denoted by S1 - S4. Site classes A and B correspond to hard rock and rock, Site Class C corresponds to soft rock and very stiff / very dense soil, and Site Classes D and E correspond to stiff soil and soft soil. A sixth site class, F, is defined for soils requiring site-specific evaluations. Both Fa and Fv are functions of the site class, and also of the level of seismic hazard on rock, defined by parameters such as Aa and Av (1994 NEHRP Provisions), Ss and S1 (1997 NEHRP Provisions) or Z (1997 UBC). The values of Fa and Fv decrease as the seismic hazard on rock increases due to soil nonlinearity. The greatest impact of the new factors Fa and Fv as compared with the old S factors occurs in areas of low-to-medium seismic hazard. This paper summarizes the new site provisions, explains the basis for them, and discusses ongoing studies of site amplification in recent earthquakes that may influence future code developments.

The site selection process

International Nuclear Information System (INIS)

Kittel, J.H.

1989-01-01

One of the most arduous tasks associated with the management of radioactive wastes is the siting of new disposal facilities. Experience has shown that the performance of the disposal facility during and after disposal operations is critically dependent on the characteristics of the site itself. The site selection process consists of defining needs and objectives, identifying geographic regions of interest, screening and selecting candidate sites, collecting data on the candidate sites, and finally selecting the preferred site. Before the site selection procedures can be implemented, however, a formal legal system must be in place that defines broad objectives and, most importantly, clearly establishes responsibilities and accompanying authorities for the decision-making steps in the procedure. Site selection authorities should make every effort to develop trust and credibility with the public, local officials, and the news media. The responsibilities of supporting agencies must also be spelled out. Finally, a stable funding arrangement must be established so that activities such as data collection can proceed without interruption. Several examples, both international and within the US, are given

Site environmental programs

Energy Technology Data Exchange (ETDEWEB)

Schmidt, J.W.; Hanf, R.W.

1995-06-01

This section of the 1994 Hanford Site Environmental Report summarizes the site environmental programs. Effluent monitoring and environmental surveillance programs monitor for impacts from operations in several areas. The first area consists of the point of possible release into the environment. The second area consists of possible contamination adjacent to DOE facilities, and the third area is the general environment both on and off the site.

Site environmental programs

International Nuclear Information System (INIS)

Schmidt, J.W.; Hanf, R.W.

1995-01-01

This section of the 1994 Hanford Site Environmental Report summarizes the site environmental programs. Effluent monitoring and environmental surveillance programs monitor for impacts from operations in several areas. The first area consists of the point of possible release into the environment. The second area consists of possible contamination adjacent to DOE facilities, and the third area is the general environment both on and off the site

LLNL Experimental Test Site (Site 300) Potable Water System Operations Plan

Energy Technology Data Exchange (ETDEWEB)

Ocampo, R. P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bellah, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2015-09-14

The existing Lawrence Livermore National Laboratory (LLNL) Site 300 drinking water system operation schematic is shown in Figures 1 and 2 below. The sources of water are from two Site 300 wells (Well #18 and Well #20) and San Francisco Public Utilities Commission (SFPUC) Hetch-Hetchy water through the Thomas shaft pumping station. Currently, Well #20 with 300 gallons per minute (gpm) pump capacity is the primary source of well water used during the months of September through July, while Well #18 with 225 gpm pump capacity is the source of well water for the month of August. The well water is chlorinated using sodium hypochlorite to provide required residual chlorine throughout Site 300. Well water chlorination is covered in the Lawrence Livermore National Laboratory Experimental Test Site (Site 300) Chlorination Plan (“the Chlorination Plan”; LLNL-TR-642903; current version dated August 2013). The third source of water is the SFPUC Hetch-Hetchy Water System through the Thomas shaft facility with a 150 gpm pump capacity. At the Thomas shaft station the pumped water is treated through SFPUC-owned and operated ultraviolet (UV) reactor disinfection units on its way to Site 300. The Thomas Shaft Hetch- Hetchy water line is connected to the Site 300 water system through the line common to Well pumps #18 and #20 at valve box #1.

Inter-Site Consistency at a Multi-Site Psychiatry Clerkship

Science.gov (United States)

Shultes von Schlageter, Margo; Park, EunMi; Tucker, Phebe

2006-01-01

Objective: This study examines the effects of clinical site assignment within a multiple-site psychiatry clerkship program on the convergent outcome of the National Board of Medical Examiners (NBME) subject examination. Method: NBME scores, controlled for baseline pre-clerkship knowledge base as measured by second year human behavior scores, were…

NRC staff site characterization analysis of the Department of Energy's Site Characterization Plan, Yucca Mountain Site, Nevada

International Nuclear Information System (INIS)

1989-08-01

This Site Characterization Analysis (SCA) documents the NRC staff's concerns resulting from its review of the US Department of Energy's (DOE's) Site Characterization Plan (SCP) for the Yucca Mountain site in southern Nevada, which is the candidate site selected for characterization as the nation's first geologic repository for high-level radioactive waste. DOE's SCP explains how DOE plans to obtain the information necessary to determine the suitability of the Yucca Mountain site for a repository. NRC's specific objections related to the SCP, and major comments and recommendations on the various parts of DOE's program, are presented in SCA Section 2, Director's Comments and Recommendations. Section 3 contains summaries of the NRC staff's concerns for each specific program, and Section 4 contains NRC staff point papers which set forth in greater detail particular staff concerns regarding DOE's program. Appendix A presents NRC staff evaluations of those NRC staff Consultation Draft SCP concerns that NRC considers resolved on the basis of the SCP. This SCA fulfills NRC's responsibilities with respect to DOE's SCP as specified by the Nuclear Waste Policy Act (NWPA) and 10 CFR 60.18. 192 refs., 2 tabs

Superfund Site Information - Site Sampling Data

Data.gov (United States)

U.S. Environmental Protection Agency — This asset includes Superfund site-specific sampling information including location of samples, types of samples, and analytical chemistry characteristics of...

Experience with the operation of a solar central heating system in Friedrichshafen/Wiggenhausen-Sued; Betriebserfahrungen mit der solaren Nahwaermeversorgung in Friedrichshafen/Wiggenhausen-Sued

Energy Technology Data Exchange (ETDEWEB)

Stanzel, B.; Gawantka, F. [Technische Werke Friedrichshafen GmbH, Friedrichshafen (Germany)

1998-12-31

The ideas, concepts and pilot plants for solar central heating systems developed by the Institute for Thermodynamics and Thermal Engineering of Stuttgart University were implemented by the Steinbeis-Transfer Centre for Energy, Building and Solar Engineering. In order to improve the economic efficiency of solar central heating with long-term storage a pilot plant with a heat storage tank of 12,000 cubic metres was built in Wiggenhausen-Sued. The `Technische Werke Friedrichshafen` (TWF) is in charge of the project `Solar City Wiggenhausen-Sued`. This company built the plant and also operates and maintains it. (orig.) [Deutsch] Die Ideen, Konzepte und erste Pilotanlagen zur solaren Nahwaerme werden seit Mitte der achtziger Jahre vom Institut fuer Thermodynamik und Waermetechnik (ITW) der Universitaet Stuttgart entwickelt und vom Steinbeis-Transferzentrum Energie-, Gebaeude- und Solartechnik umgesetzt. Um die solare Nahwaermeversorgung mit Langzeit-Waermespeicher der Wirtschaftlichkeit etwas naeher zu bringen, wurde eine Pilotanlage mit einem 12.000 m{sup 3} grossen Waermespeicher in Wiggenhausen-Sued gebaut. Mit diesem Pilotprojekt soll neben der technischen Durchfuehrbarkeit die Kostendegression durch steigende Anlagengroesse nachgewiesen werden. Als Energiedienstleistungsunternehmen hat die Technische Werke Friedrichshafen GmbH (TWF) die technische und kaufmaennische Durchfuehrung des Projektes `Solarstadt Wiggenhausen-Sued` uebernommen. Sie errichtete, betreibt und wartet die Anlage. (orig.)

Accounting for religieus sensibilities in social intervention: A supplement to Donkers’ models of change

Directory of Open Access Journals (Sweden)

Timothy Schilling

2006-06-01

Full Text Available In deze bijdrage wordt nagegaan in hoeverre de drie veranderkundige modellen van Donkers adequaat zijn als het gaat om de positionering van sociale interventies die zijn geïnspireerd door het geloof. Aan de hand van het werk van de Brothers of the Christians Schools in Manhattan, betoogt de auteur dat het sociaal-technologische model, het persoongeoriënteerde model en het maatschappijkritische model ontoereikend zijn om dit soort werk te plaatsen. In geen van deze modellen wordt namelijk plaats ingeruimd voor een ervaringshorizon die verder reikt dan de persoon in relatie tot de maatschappij. Terwijl voor een gelovige een horizon van de eeuwigheid of het concept van God een belangrijke rol vervult in de motivatie, het doel en het begrip van een sociale interventie. Via gebed wordt God betrokken in de relatie tussen werker en cliënt en in het veranderingsproces. De auteur stelt daarom een vierde, op het geloof gebaseerd model voor dat, zo hoopt hij, een goed interpretatiekader kan vormen voor vanuit religieuze achtergrond ingezette sociale interventies. Op die manier kan wellicht meer inzicht worden verkregen in hoe en waarom het geloof werkzaam is in de inzet voor sociale veranderingen, niet alleen het christelijk geloof, waar zijn casus betrekking op heeft, maar mogelijk ook andere religies.

Slavery, religion, and abolition in Suriname

Directory of Open Access Journals (Sweden)

Johannes Postma

1997-07-01

Full Text Available [First paragraph] "Om werk van jullie te hebben": Plantageleven in Suriname, 1730-1750. RUDI OTTO BEELDSNIJDER. Utrecht: Vakgroep Culturele Antropologie - Bronnen voor de Studie van Afro-Surinaamse Samenlevingen, 1994. xii + 351 pp. (Paper NLG 35.00 Surinaams contrast: Roofbouw en overleven in een Caraibische plantagekolonie 1750-1863. ALEX VAN STIPRIAAN. Leiden: KITLV Press, 1995. xiii + 494 pp. (Paper NLG 60.00 Strijders voor het Lam: Leven en werk van Herrnhutter broeders en zusters in Suriname, 1735-1900. MARIA LENDERS. Leiden: KITLV Press, 1996. xii + 451 pp. (Paper NLG 65.00 Fifty Years Later: Antislavery, Capitalism and Modernity in the Dutch Orbit. GERT OOSTINDIE (ed.. Leiden: KITLV Press, 1995; Pittsburgh: University of Pittsburgh Press, 1996. viii + 272 pp. (Paper NLG 45.00, US$ 22.50, Cloth US$ 45.00 The publication of the books under review is evidence of a growing scholarly interest in the history of Dutch activities in the Atlantic. Three of them are doctoral dissertations on Suriname history; the fourth contains the published proceedings of a conference held in 1993 that focused on the abolition of slavery in the Dutch colonies. Three were published by the Royal Institute of Linguistics and Anthropology (KITLV, which exhibits an increasing interest in publishing scholarly books about Dutch overseas history.

Review: Gerd Jüttemann (Hrsg. (2013. Die Entwicklung der Psyche in der Geschichte der Menschheit

Directory of Open Access Journals (Sweden)

Uwe Krebs

2015-03-01

Full Text Available Der Vorbereitungsband für die Reihe "Die Psychogenese der Menschheit" – ein Sammelband aus 32 Beiträgen, betitelt "Die Entwicklung der Psyche in der Geschichte der Menschheit" und 2013 herausgegeben von Gerd JÜTTEMANN – wird in dieser Besprechung in mehreren Schritten vorgestellt und bewertet. Zunächst wird kontextuell argumentiert, dass die bewährte, empirisch-experimentelle Methodologie der Psychologie zur Vernachlässigung weiterer Erkenntnisverfahren führte, die bei Themen wie dem hier zu besprechenden Werk allein verbleiben und die kurz angesprochen werden. Sodann wird das Werk im Überblick knapp dargestellt und die außergewöhnliche Heterogenität in Inhalten und Methoden betont. Die Besprechung einzelner Beiträge, die nach dem Gesichtspunkt großer Unterschiedlichkeit ausgewählt wurden, schließt sich an. Die abschließende Gesamtbewertung betont den lückenhaften Forschungsstand, die Notwendigkeit der allein verbleibenden qualitativen Methodik mit ihren verschiedenen Möglichkeiten und nennt Desiderata künftigen Vorgehens für diesen thematisch und methodisch interessanten Auftakt-Band, der insbesondere durch Dichte und Verschiedenheit der Beiträge beeindruckt. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1502219

Role salience of dual-career women managers

Directory of Open Access Journals (Sweden)

Anthony V Naidoo

2002-10-01

Full Text Available This study examines and contrasts the level of role participation, commitment and value expectation that dual career women invest in contending work and family roles. While the 162 married women managers were found to participate significantly more in the work role, they indicated greater commitment to and value expectation from the home and family role. A significant positive correlation between the commitment to the work role and commitment to the home and family role suggests that dual-career women may experience work and home as complimentary rather than conflicting roles. For dual-career women, work salience and career salience were found to be moderately correlated. Opsomming In hierdie studie word die vlakke van rol-deelname, rol-toegewydheid en rol-waardeverwagting wat dubbelloopbaan vroue onderskeidelik in die werk-en familierol investeer, gekonstrasteer. Terwyl dit geblyk het dat 162 getroude vroulike bestuurders beduidend meer deelneem in die werkrol, het hulle hoër toegewydheid en waardeverwagtings teenoor die huis-en-familie rol getoon. ‘n Beduidende positiewe korrelasie is gevind tussen toegewydheid tot die werksrol en toegewydheid tot die huis-en-familierol. Hierdie bevinding suggereer dat dubbelloopbaan vroue hulle werk en familie-rolle as komplimenterend eerder as konflikterend ervaar. Dit het verder geblyk dat werkrolbelangrikheid en loopbaanbelangrikheid matig gekorreleer is.

STEM VQ Method, Using Scanning Transmission Electron Microscopy (STEM) for Accurate Virus Quantification

Science.gov (United States)

2017-02-02

WEEV in Ontario, Canada in 194126. This virus has a passage history including both animals and cell culture. Biosafety level (BSL-)-3 laboratory...Agarose-Based Plaque Assay Each virus stock was quantitated by standard agarose-based plaque assay23...samples used here were well prepared and the standard macro was used. As we have developed this method we have observed that while inferior

Implementing ‘Site BIM’

DEFF Research Database (Denmark)

Davies, Richard; Harty, Chris

2013-01-01

Numerous Building Information Modelling (BIM) tools are well established and potentially beneficial in certain uses. However, issues of adoption and implementation persist, particularly for on-site use of BIM tools in the construction phase. We describe an empirical case-study of the implementation...... of an innovative ‘Site BIM’ system on a major hospital construction project. The main contractor on the project developed BIM-enabled tools to allow site workers using mobile tablet personal computers to access design information and to capture work quality and progress data on-site. Accounts show that ‘Site BIM...

Olkiluoto site description 2011

International Nuclear Information System (INIS)

2012-12-01

This fourth version of the Olkiluoto Site Report, produced by the OMTF (Olkiluoto Modelling Task Force), updates the Olkiluoto Site Report 2008 with the data and knowledge obtained up to December 2010. A descriptive model of the site (the Site Descriptive Model, SDM), i.e. a model describing the geological and hydrogeological structure of the site, properties of the bedrock and the groundwater and its flow, and the associated interacting processes and mechanisms. The SDM is divided into six parts: surface system, geology, rock mechanics, hydrogeology, hydrogeochemistry and transport properties

Olkiluoto site description 2011

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-12-15

This fourth version of the Olkiluoto Site Report, produced by the OMTF (Olkiluoto Modelling Task Force), updates the Olkiluoto Site Report 2008 with the data and knowledge obtained up to December 2010. A descriptive model of the site (the Site Descriptive Model, SDM), i.e. a model describing the geological and hydrogeological structure of the site, properties of the bedrock and the groundwater and its flow, and the associated interacting processes and mechanisms. The SDM is divided into six parts: surface system, geology, rock mechanics, hydrogeology, hydrogeochemistry and transport properties.

Site Selection for Surplus Plutonium Disposition Facilities at the Savannah River Site

International Nuclear Information System (INIS)

Wike, L.D.

2000-01-01

A site selection study was conducted to evaluate locations for the proposed Surplus Plutonium Disposition Facilities. Facilities to be located include the Mixed Oxide (MOX) Fuel Fabrication Facility, the Pit Disassembly and Conversion Facility (PDCF), and the Plutonium Immobilization Project (PIP) facility. Objectives of the study include: (1) Confirm that the Department of Energy (DOE) selected locations for the MOX and PDCF were suitable based on selected siting criteria, (2) Recommend a site in the vicinity of F Area that is suitable for the PIP, and (3) Identify alternative suitable sites for one or more of these facilities in the event that further geotechnical characterization or other considerations result in disqualification of a currently proposed site

Methods for estimating on-site ambient air concentrations at disposal sites

International Nuclear Information System (INIS)

Hwang, S.T.

1987-01-01

Currently, Gaussian type dispersion modeling and point source approximation are combined to estimate the ambient air concentrations of pollutants dispersed downwind of an areawide emission source, using the approach of virtual point source approximation. This Gaussian dispersion modeling becomes less accurate as the receptor comes closer to the source, and becomes inapplicable for the estimation of on-site ambient air concentrations at disposal sites. Partial differential equations are solved with appropriate boundary conditions for use in estimating the on-site concentrations in the ambient air impacted by emissions from an area source such as land disposal sites. Two variations of solution techniques are presented, and their predictions are compared

Site Rehabilitation Completion Report with No Further Action Proposal for the Northeast Site

Energy Technology Data Exchange (ETDEWEB)

Daniel, Joe [Stoller Newport News Technology, Inc., Grand Junction, CO (United States); Tabor, Charles [Stoller Newport News Technology, Inc., Grand Junction, CO (United States); Survochak, Scott [U.S. Department of Energy, Office of Legacy Management, Grand Junction, CO (United States)

2013-05-01

The purpose of this Site Rehabilitation Completion Report is to present the post-active-remediation monitoring results for the Northeast Site and to propose No Further Action with Controls. This document includes information required by Chapter 62-780.750(4)(d), 62-780.750(6), and 62-780.600(8)(a)27 Florida Administrative Code (F.A.C.). The Closure Monitoring Plan for the Northeast Site and 4.5 Acre Site (DOE 2009a) describes the approach for post-active-remediation monitoring. The Young - Rainey Science, Technology, and Research Center (STAR Center) is a former U.S. Department of Energy (DOE) facility constructed in the mid-1950s. The 99-acre STAR Center is located in Largo, Florida. The Northeast Site is located in the northeast corner of the STAR Center. The Northeast Site meets all the requirements for an RMO II closure—No Further Action with Controls. DOE is nearing completion of a restrictive covenant for the Northeast Site. DOE has completed post-active-remediation monitoring at the Northeast Site as of September 2012. No additional monitoring will be conducted.

Expedited Site Characterization: A rapid, cost-effective process for preremedial site characterization

International Nuclear Information System (INIS)

Burton, J.C.; Walker, J.L.; Jennings, T.V.; Aggarwal, P.K.; Hastings, B.; Meyer, W.T.; Rose, C.M.; Rosignolo, C.L.

1993-01-01

Argonne National Laboratory has developed a unique, cost- and time-effective, technically innovative process for preremedial site characterization, referred to as Expedited Site Characterization (ESC). The cost of the ESC field sampling process ranges from 1/10 to 1/5 of the cost of traditional site characterization. The time required for this ESC field activity is approximately 1/30 of that for current methods. Argonne's preremedial site investigations based on this approach have been accepted by the appropriate regulatory agencies. The ESC process is flexible and neither site nor contaminant dependent. The process has been successfully tested and applied in site investigations of multiple contaminated landfills in New Mexico (for the US Department of the Interior's Bureau of Land Management [BLM]) and at former grain storage facilities in Nebraska and Kansas, contaminated with carbon tetrachloride (for the Department of Agriculture's Commodity Credit Corporation [CCC/USDA]). A working demonstration of this process was sponsored by the US Department of Energy (DOE) Office of Technology Development as a model of the methodology needed to accelerate site characterizations at DOE facilities. This report describes the application of the process in New Mexico, Nebraska and Kansas

Site observational work plan for the UMTRA project site at Grand Junction, Colorado

International Nuclear Information System (INIS)

1996-01-01

This site observational work plan (SOWP) is one of the first Uranium Mill Tailings Remedial Action (UMTRA) Ground Water Project documents developed to select a compliance strategy that meets the UMTRA ground water standards for the Grand Junction site. This SOWP applies information about the Grand Junction site to the compliance strategy selection framework developed in the UMTRA Ground Water Project draft programmatic environmental impact statement. This risk-based, decision-making framework identifies the decision logic for selecting compliance strategies that could be used to meet the ground water standards. The US Department of Energy (DOE) goal is to implement a cost-effective site strategy that complies with the ground water standards and protects human health and the environment. Based on an evaluation of the site characterization and risk assessment data available for the preparation of this SOWP, DOE proposes that the most likely compliance strategy for the Grand Junction site is no remediation with the application of supplemental standards. This proposed strategy is based on a conceptual site model that indicates site-related contamination is confined to a limited-use aquifer as defined in the ground water standards. The conceptual model demonstrates that the uranium processing-related contamination at the site has affected the unconfined alluvial aquifer, but not the deeper confined aquifer

Searching your site`s management information systems

Energy Technology Data Exchange (ETDEWEB)

Marquez, W.; Rollin, C. [S.M. Stoller Corp., Boulder, CO (United States)

1994-12-31

The Department of Energy`s guidelines for the Baseline Environmental Management Report (BEMR) encourage the use of existing data when compiling information. Specific systems mentioned include the Progress Tracking System, the Mixed-Waste Inventory Report, the Waste Management Information System, DOE 4700.1-related systems, Programmatic Environmental Impact Statement (PEIS) data, and existing Work Breakdown Structures. In addition to these DOE-Headquarters tracking and reporting systems, there are a number of site systems that will be relied upon to produce the BEMR, including: (1) site management control and cost tracking systems; (2) commitment/issues tracking systems; (3) program-specific internal tracking systems; (4) Site material/equipment inventory systems. New requirements have often prompted the creation of new, customized tracking systems. This is a very time and money consuming process. As the BEMR Management Plan emphasizes, an effort should be made to use the information in existing tracking systems. Because of the wealth of information currently available from in-place systems, development of a new tracking system should be a last resort.

Application of the Integrated Site and Environment Data Management System for LILW Disposal Site

International Nuclear Information System (INIS)

Lee, Ji Hoon; Lee, Eun Yong; Kim, Chang Lak

2007-01-01

During the last five years, Site Information and Total Environmental data management System(SITES) has been developed. SITES is an integrated program for overall data acquisition, environmental monitoring, and safety analysis. SITES is composed of three main modules, such as site database system (SECURE), safety assessment system (SAINT) and environmental monitoring system (SUDAL). In general, for the safe management of radioactive waste repository, the information of site environment should be collected and managed systematically from the initial site survey. For this, SECURE module manages its data for the site characterization, environmental information, and radioactive environmental information etc. The purpose of SAINT module is to apply and analyze the data from SECURE. SUDAL is developed for environmental monitoring of the radioactive waste repository. Separately, it is ready to open to the public for offering partial information

Nevada Test Site Environmental Report 2009, Attachment A: Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy Wills, ed.

2010-09-13

This attachment expands on the general description of the Nevada Test Site (NTS) presented in the Introduction to the Nevada Test Site Environmental Report 2009. Included are subsections that summarize the site’s geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site’s environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site that afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Ocean Disposal Site Monitoring

Science.gov (United States)

EPA is responsible for managing all designated ocean disposal sites. Surveys are conducted to identify appropriate locations for ocean disposal sites and to monitor the impacts of regulated dumping at the disposal sites.

Site characterization criteria (DOE-STD-1022-94) for natural phenomena hazards at DOE sites

International Nuclear Information System (INIS)

Chen, J.C.; Ueng, T.S.; Boissonnade, A.C.

1995-12-01

This paper briefly summarizes requirements of site characterization for Natural Phenomena Hazards (NPH) at DOE sites. In order to comply with DOE Order 5480.28, site characterization criteria has been developed to provide site-specific information needed for development of NPH assessment criteria. Appropriate approaches are outlined to ensure that the current state-of-the-art methodologies and procedures are used in the site characterization. General and detailed site characterization requirements are provided in the areas of meteorology, hydrology, geology, seismology and geotechnical studies

Non-Invasive Seismic Methods for Earthquake Site Classification Applied to Ontario Bridge Sites

Science.gov (United States)

Bilson Darko, A.; Molnar, S.; Sadrekarimi, A.

2017-12-01

How a site responds to earthquake shaking and its corresponding damage is largely influenced by the underlying ground conditions through which it propagates. The effects of site conditions on propagating seismic waves can be predicted from measurements of the shear wave velocity (Vs) of the soil layer(s) and the impedance ratio between bedrock and soil. Currently the seismic design of new buildings and bridges (2015 Canadian building and bridge codes) requires determination of the time-averaged shear-wave velocity of the upper 30 metres (Vs30) of a given site. In this study, two in situ Vs profiling methods; Multichannel Analysis of Surface Waves (MASW) and Ambient Vibration Array (AVA) methods are used to determine Vs30 at chosen bridge sites in Ontario, Canada. Both active-source (MASW) and passive-source (AVA) surface wave methods are used at each bridge site to obtain Rayleigh-wave phase velocities over a wide frequency bandwidth. The dispersion curve is jointly inverted with each site's amplification function (microtremor horizontal-to-vertical spectral ratio) to obtain shear-wave velocity profile(s). We apply our non-invasive testing at three major infrastructure projects, e.g., five bridge sites along the Rt. Hon. Herb Gray Parkway in Windsor, Ontario. Our non-invasive testing is co-located with previous invasive testing, including Standard Penetration Test (SPT), Cone Penetration Test and downhole Vs data. Correlations between SPT blowcount and Vs are developed for the different soil types sampled at our Ontario bridge sites. A robust earthquake site classification procedure (reliable Vs30 estimates) for bridge sites across Ontario is evaluated from available combinations of invasive and non-invasive site characterization methods.

DOE site performance assessment activities

International Nuclear Information System (INIS)

1990-07-01

Information on performance assessment capabilities and activities was collected from eight DOE sites. All eight sites either currently dispose of low-level radioactive waste (LLW) or plan to dispose of LLW in the near future. A survey questionnaire was developed and sent to key individuals involved in DOE Order 5820.2A performance assessment activities at each site. The sites surveyed included: Hanford Site (Hanford), Idaho National Engineering Laboratory (INEL), Los Alamos National Laboratory (LANL), Nevada Test Site (NTS), Oak Ridge National Laboratory (ORNL), Paducah Gaseous Diffusion Plant (Paducah), Portsmouth Gaseous Diffusion Plant (Portsmouth), and Savannah River Site (SRS). The questionnaire addressed all aspects of the performance assessment process; from waste source term to dose conversion factors. This report presents the information developed from the site questionnaire and provides a comparison of site-specific performance assessment approaches, data needs, and ongoing and planned activities. All sites are engaged in completing the radioactive waste disposal facility performance assessment required by DOE Order 5820.2A. Each site has achieved various degrees of progress and have identified a set of critical needs. Within several areas, however, the sites identified common needs and questions

Nevada Test Site Environmental Report 2006 and Site Description (Volume 1)

Energy Technology Data Exchange (ETDEWEB)

Cathy Wills

2007-10-01

The Nevada Test Site Environmental Report 2006 (NTSER) was prepared to meet the information needs of the public and the requirements and guidelines of the U.S. Department of Energy (DOE) for annual site environmental reports. It was prepared by National Security Technologies, LLC (NSTec). This Executive Summary presents the purpose of the document, the major programs conducted at the Nevada Test Site (NTS), NTS key environmental initiatives, radiological releases and potential doses to the public resulting from site operations, a summary of nonradiological releases, implementation status of the NTS Environmental Management System, a summary of compliance with environmental regulations, pollution prevention and waste minimization accomplishments, and significant environmental accomplishments. Much of the content of this Executive Summary is also presented in a separate stand-alone pamphlet titled Nevada Test Site Environmental Report Summary 2006 produced to be a more cost-effective means of distributing information contained in the NTSER to interested DOE stakeholders.

Site selection - siting of the final repository for spent nuclear fuel

International Nuclear Information System (INIS)

2011-03-01

SKB has selected Forsmark as the site for the final repository for spent nuclear fuel. The site selection is the end result of an extensive siting process that began in the early 1990s. The strategy and plan for the work was based on experience from investigations and development work over a period of more than ten years prior to then. This document describes the siting work and SKB's choice of site for the final repository. It also presents the information on which the choice was based and the reasons for the decisions made along the way. The document comprises Appendix PV to applications under the Nuclear Activities Act and the Environmental Code for licences to build and operate an encapsulation plant adjacent to the central interim storage facility for spent nuclear fuel in Oskarshamn, and to build and operate a final repository for spent nuclear fuel in Forsmark in Oesthammar Municipality

Site selection - siting of the final repository for spent nuclear fuel

Energy Technology Data Exchange (ETDEWEB)

2011-03-15

SKB has selected Forsmark as the site for the final repository for spent nuclear fuel. The site selection is the end result of an extensive siting process that began in the early 1990s. The strategy and plan for the work was based on experience from investigations and development work over a period of more than ten years prior to then. This document describes the siting work and SKB's choice of site for the final repository. It also presents the information on which the choice was based and the reasons for the decisions made along the way. The document comprises Appendix PV to applications under the Nuclear Activities Act and the Environmental Code for licences to build and operate an encapsulation plant adjacent to the central interim storage facility for spent nuclear fuel in Oskarshamn, and to build and operate a final repository for spent nuclear fuel in Forsmark in Oesthammar Municipality

Nevada Test Site Environmental Report 2006 and Site Description (Volume 1)

International Nuclear Information System (INIS)

Cathy Wills

2007-01-01

The Nevada Test Site Environmental Report 2006 (NTSER) was prepared to meet the information needs of the public and the requirements and guidelines of the U.S. Department of Energy (DOE) for annual site environmental reports. It was prepared by National Security Technologies, LLC (NSTec). This Executive Summary presents the purpose of the document, the major programs conducted at the Nevada Test Site (NTS), NTS key environmental initiatives, radiological releases and potential doses to the public resulting from site operations, a summary of nonradiological releases, implementation status of the NTS Environmental Management System, a summary of compliance with environmental regulations, pollution prevention and waste minimization accomplishments, and significant environmental accomplishments. Much of the content of this Executive Summary is also presented in a separate stand-alone pamphlet titled Nevada Test Site Environmental Report Summary 2006 produced to be a more cost-effective means of distributing information contained in the NTSER to interested DOE stakeholders

Site observational work plan for the UMTRA Project site at Falls City, Texas

International Nuclear Information System (INIS)

1995-06-01

Produced by the US Department of Energy (DOE), this site observational work plan (SOWP) will be used to determine site-specific activities to comply with the US Environmental Protection Agency (EPA) ground water standards at this Uranium Mill Tailings Remedial Action (UMTRA) Project site. The purpose of the SOWP is to recommend a site-specific ground water compliance strategy at the Falls City UMTRA Project site. The Falls City SOWP presents a comprehensive summary of site hydrogeological data, delineates a conceptual model of the aquifer system, and discusses the origins of milling-related ground water contamination. It also defines the magnitude of ground water contamination, potential environmental and health risks associated with ground water contamination and data gaps, and targets a proposed compliance strategy

Wer sich den Göttern widersetzt, der stirbt jung : Untersuchung der Unvermeidbarkeit des Suizids in Die Leiden des jungen Werthers hinsichtlich der Strömung des „Sturm und Drang“

OpenAIRE

Andersson, Rasmus

2015-01-01

Der Ausgang des Romans Die Leiden des Jungen Werther (1774, von Johann Wolfgang von Goethe) wird beim ersten Anblick oft als tragische Folge einer unglücklichen und unerwiderten Liebe zu Lotte angesehen. In dieser vorliegenden Arbeit wird der weit erforschten Frage der Unvermeidbarkeit des Suizids im Werk eine alternative Deutung geliefert. Diese ist außerhalb des Romans angesiedelt, und zeigt, dass der Suizid schon in der Epoche angelegt ist.

Social inclusion in diverse work settings

OpenAIRE

Jansen, W.S.

2015-01-01

Het ervaren van sociale inclusie op het werk is essentieel voor het welbevinden en presteren van werknemers. Echter, terwijl inclusie relatief gemakkelijk te bewerkstelligen is wanneer collega’s demografisch gezien op elkaar lijken, is dit moeilijker wanneer collega's sterk van elkaar verschillen. Dit proefschrift tracht een begrip te creëren van hoe inclusie in demografisch diverse werkomgevingen bewerkstelligd kan worden. Hiertoe is allereerst vastgesteld wat inclusie precies is en hoe dit ...

Kulturmorphologie als Zivilisationskritik

DEFF Research Database (Denmark)

Peters, Rikke Alberg

2010-01-01

Der Untergang des Abendlandes wird oft als dasjenige Werk betrachtet, das am tiefsten die national gefärbte Gegenüberstellung von Kultur und Zivilisation in der Zwischenkriegszeit geprägt und propagiert hat. Wie auch bei anderen Autoren der Konservativen Revolution, vor allem bei Thomas Mann und...... Arthur Moeller van den Bruck, tritt der Begriff ‚Kultur’ bei Spengler als normativer Wertbegriff auf, der im Kontrast zu einer degenerierten und seelenlosen Zivilisation steht....

Über die normativen Implikationen des Ordoliberalismus für die moderne Wirtschaftsethik

OpenAIRE

Klump, Rainer; Wörsdörfer, Manuel

2009-01-01

"Bei der Rezeption der ordoliberalen Freiburger Schule wurde bislang die wirtschaftsethische Perspektive weitgehend vernachlässigt. Der Aufsatz gibt vertiefte Einblicke in das ethisch-normative Denken des Ordoliberalismus am Beispiel des Werkes von Walter Eucken. Dabei wird es neben der Bestimmung der Sozialen Marktwirtschaft als funktionsfähige und menschenwürdige Ordnung um Euckens an Kant angelehntes Freiheitsverständnis gehen sowie um eine Einordnung Euckens in die moderne Wirtschafts- un...

The Role of Preferences in the Decision-making Behaviour of Food Producers and Consumers in Flanders

OpenAIRE

Vandermersch, Mieke

2006-01-01

De rode draad in deze doctoraatsthesis is het zoeken naar een verklaring voor de besluitvorming van producenten enerzijds en consumenten anderzi jds. Als verklarende variabelen worden ook socio-demografische variabele n onderzocht, maar het hoofdaandeel van dit werk gaat over het belang va n ‘voorkeuren’ als verklarende variabelen voor besluitvorming. De beslis singen die worden onderzocht zijn beslissingen met betrekking tot de ont wikkeling van het landbouwbedrijf en het inkomen op het land...

Kalevipoeg tänapäeval - ühe tulevase Euroopa kultuuri document humain : psühholoogilis-antropoloogilisi aspekte / Peter Petersen ; tõlkinud Krista Räni

Index Scriptorium Estoniae

Petersen, Peter, 1933-

2003-01-01

Lisa 1. William Butler Yeats. Ta igatseb endale taevakangaid / tõlkinud Märt Väljataga, lk. 2587 ; Lisa 2. Novalis. Neue Fragmente. Nr. 393 (Novalis. Werke und Briefe. Stuttgart ; Hamburg : Deutscher Bücherbund, 1962), lk. 2587-2588 ; Lisa 3. Tabel väärtuste kohta, mida Kalevipoja-eeposes esile tuuakse, lk. 2588. Bibl. lk. 2589-2590. Tõlgitud käsikirjast: "Kalevipoeg heute - document humain einer künftigen Kultur Europas: psychologisch-anthropologische Aspekte"

Blinde alfabet: ʼn Moedswillige Willem Boshoff reken af met meerderwaardigheid – ʼn neo-Marxistiese interpretasie

OpenAIRE

Swanepoel, Rita

2013-01-01

In heelwat van sy taalgebaseerde konseptuele installasies moedig die kunstenaar Willem Boshoff aanskouers van sy werke tot gesprekvoering aan. Die doel van die gesprekke is hoofsaaklik om die dominasie van sogenaamde meerderwaardiges as "superieur" en die "norm" te ondermyn. Hy doen dit deur die bemagtiging van die "afwykendes" of "abnormales" om die betekenis van die kunswerk aan die "meerderwaardiges" te verduidelik. Hierdie aanslag van Boshoff ondersoek en illustreer ek in hierdie artikel ...

Site-Specific Seismic Site Response Model for the Waste Treatment Plant, Hanford, Washington

Energy Technology Data Exchange (ETDEWEB)

Rohay, Alan C.; Reidel, Steve P.

2005-02-24

This interim report documents the collection of site-specific geologic and geophysical data characterizing the Waste Treatment Plant site and the modeling of the site-specific structure response to earthquake ground motions.

Technical know-how of site descriptive modeling for site characterization - 59089

International Nuclear Information System (INIS)

Saegusa, Hiromitsu; Onoe, Hironori; Doke, Ryosuke; Niizato, Tadafumi; Yasue, Ken-ichi

2012-01-01

The site descriptive model covering the current status of characteristics of geological environment and the site evolution model for estimation of the long-term evolution of site conditions are used to integrate multi-disciplinary investigation results. It is important to evaluate uncertainties in the models, to specify issues regarding the uncertainties and to prioritize the resolution of specified issues, for the planning of site characterization. There is a large quantity of technical know-how in the modeling process. It is important to record the technical know-how with transparency and traceability, since site characterization projects generally need long duration. The transfer of the technical know-how accumulated in the research and development (R and D) phase to the implementation phase is equally important. The aim of this study is to support the planning of initial surface-based site characterizations based on the technical know-how accumulated from the underground research laboratory projects. These projects are broad scientific studies of the deep geological environment and provide a technical basis for the geological disposal of high-level radioactive wastes. In this study, a comprehensive task flow from acquisition of existing data to planning of field investigations through the modeling has been specified. Specific task flow and decision-making process to perform the tasks have been specified. (authors)

Site observational work plan for the UMTRA Project Site at Grand Junction, Colorado

International Nuclear Information System (INIS)

1996-03-01

The U.S. Department of Energy (DOE) has prepared this initial site observational work plan (SOWP) for the Uranium Mill Tailings Remedial Action (UMTRA) Project site in Grand Junction, Colorado. This SOWP is one of the first UMTRA Ground Water Project documents developed to select a compliance strategy that meets the UMTRA ground water standards (40 CFR Part 192, as amended by 60 FR 2854) for the Grand Junction site. This SOWP applies information about the Grand Junction site to the compliance strategy selection framework developed in the UMTRA Ground Water Project draft programmatic environmental impact statement (PEIS). This risk-based, decision-making framework identifies the decision logic for selecting compliance strategies that could be used to meet the ground water standards. The DOE goal is to use the observational method to implement a cost-effective site strategy that complies with the ground water standards and protects human health and the environment. Based on an evaluation of the site characterization and risk assessment data available for the preparation of this SOWP, DOE proposes that the most likely compliance strategy for the Grand Junction site is no remediation based on the application of supplemental standards. This proposed strategy is based on a conceptual site model that indicates site-related contamination is confined to a limited-use aquifer as defined in the ground water standards

Site enforcement tracking system (SETS): PRP listing by site for region 9

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 8

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 10

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 3

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 2

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 5

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 6

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number