WorldWideScience

Sample records for single-pot derivatisation strategy

  1. Azide- and alkyne-derivatised α-amino acids

    DEFF Research Database (Denmark)

    Johansson, Karl Henrik; Pedersen, D.S.

    2012-01-01

    With the emergence of the copper-catalysed Huisgen cycloaddition the use of azide- and alkyne-derivatised α-amino acids has found widespread use within most chemistry disciplines. Despite a growing interest in these building blocks researchers are struggling to identify the best way for their syn......With the emergence of the copper-catalysed Huisgen cycloaddition the use of azide- and alkyne-derivatised α-amino acids has found widespread use within most chemistry disciplines. Despite a growing interest in these building blocks researchers are struggling to identify the best way...... for their synthesis. In this review we have compiled available methods for synthesising optically active azide- and alkyne-derivatised α-amino acids that can be prepared from readily available α-amino acids. We highlight a number of commonly overlooked problems associated with existing methods and direct attention...... to unexplored possibilities. Azide- and alkyne-derivatised α-amino acids are finding widespread use within most chemistry disciplines. However, it is far from clear what the best way for the synthesis of these useful building blocks is. Herein we show the available methods for synthesis of optically active...

  2. Post column derivatisation analyses review. Is post-column derivatisation incompatible with modern HPLC columns?

    Science.gov (United States)

    Jones, Andrew; Pravadali-Cekic, Sercan; Dennis, Gary R; Shalliker, R Andrew

    2015-08-19

    Post Column derivatisation (PCD) coupled with high performance liquid chromatography or ultra-high performance liquid chromatography is a powerful tool in the modern analytical laboratory, or at least it should be. One drawback with PCD techniques is the extra post-column dead volume due to reaction coils used to enable adequate reaction time and the mixing of reagents which causes peak broadening, hence a loss of separation power. This loss of efficiency is counter-productive to modern HPLC technologies, -such as UHPLC. We reviewed 87 PCD methods published from 2009 to 2014. We restricted our review to methods published between 2009 and 2014, because we were interested in the uptake of PCD methods in UHPLC environments. Our review focused on a range of system parameters including: column dimensions, stationary phase and particle size, as well as the geometry of the reaction loop. The most commonly used column in the methods investigated was not in fact a modern UHPLC version with sub-2-micron, (or even sub-3-micron) particles, but rather, work-house columns, such as, 250 × 4.6 mm i.d. columns packed with 5 μm C18 particles. Reaction loops were varied, even within the same type of analysis, but the majority of methods employed loop systems with volumes greater than 500 μL. A second part of this review illustrated briefly the effect of dead volume on column performance. The experiment evaluated the change in resolution and separation efficiency of some weak to moderately retained solutes on a 250 × 4.6 mm i.d. column packed with 5 μm particles. The data showed that reaction loops beyond 100 μL resulted in a very serious loss of performance. Our study concluded that practitioners of PCD methods largely avoid the use of UHPLC-type column formats, so yes, very much, PCD is incompatible with the modern HPLC column. Copyright © 2015. Published by Elsevier B.V.

  3. Biophysical properties of phenyl succinic acid derivatised hyaluronic acid

    DEFF Research Database (Denmark)

    Neves-Petersen, Maria Teresa; Klitgaard, Søren; Skovsen, Esben

    2010-01-01

    Modification of hyaluronic acid (HA) with aryl succinic anhydrides results in new biomedical properties of HA as compared to non-modified HA, such as more efficient skin penetration, stronger binding to the skin, and the ability to blend with hydrophobic materials. In the present study, hyaluronic...... acid has been derivatised with the anhydride form of phenyl succinic acid (PheSA). The fluorescence of PheSA was efficiently quenched by the HA matrix. HA also acted as a singlet oxygen scavenger. Fluorescence lifetime(s) of PheSA in solution and when attached to the HA matrix has been monitored...

  4. Evaluation of novel derivatisation reagents for the analysis of oxysterols

    Energy Technology Data Exchange (ETDEWEB)

    Crick, Peter J., E-mail: p.j.crick@swansea.ac.uk [Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom); Aponte, Jennifer; Bentley, T. William [Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom); Matthews, Ian [College of Engineering, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom); Wang, Yuqin [Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom); Griffiths, William J., E-mail: w.j.griffiths@swansea.ac.uk [Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom)

    2014-04-11

    Graphical abstract: - Highlights: • New derivatisation reagents for LC–MS analysis of oxysterols. • New reagents based on Girard P give high ion-currents and informative LC–MS{sup n} spectra. • Permanent charge is vital for efficient MS{sup n} fragmentation. • New reagents offer greater scope for incorporation of isotope labels. - Abstract: Oxysterols are oxidised forms of cholesterol that are intermediates in the synthesis of bile acids and steroid hormones. They are also ligands to nuclear and G protein-coupled receptors. Analysis of oxysterols in biological systems is challenging due to their low abundance coupled with their lack of a strong chromophore and poor ionisation characteristics in mass spectrometry (MS). We have previously used enzyme-assisted derivatisation for sterol analysis (EADSA) to identify and quantitate oxysterols in biological samples. This technique relies on tagging sterols with the Girard P reagent to introduce a charged quaternary ammonium group. Here, we have compared several modified Girard-like reagents and show that the permanent charge is vital for efficient MS{sup n} fragmentation. However, we find that the reagent can be extended to include sites for potential stable isotope labels without a loss of performance.

  5. Fully Automated Trimethylsilyl (TMS) Derivatisation Protocol for Metabolite Profiling by GC-MS.

    Science.gov (United States)

    Zarate, Erica; Boyle, Veronica; Rupprecht, Udo; Green, Saras; Villas-Boas, Silas G; Baker, Philip; Pinu, Farhana R

    2016-12-29

    Gas Chromatography-Mass Spectrometry (GC-MS) has long been used for metabolite profiling of a wide range of biological samples. Many derivatisation protocols are already available and among these, trimethylsilyl (TMS) derivatisation is one of the most widely used in metabolomics. However, most TMS methods rely on off-line derivatisation prior to GC-MS analysis. In the case of manual off-line TMS derivatisation, the derivative created is unstable, so reduction in recoveries occurs over time. Thus, derivatisation is carried out in small batches. Here, we present a fully automated TMS derivatisation protocol using robotic autosamplers and we also evaluate a commercial software, Maestro available from Gerstel GmbH. Because of automation, there was no waiting time of derivatised samples on the autosamplers, thus reducing degradation of unstable metabolites. Moreover, this method allowed us to overlap samples and improved throughputs. We compared data obtained from both manual and automated TMS methods performed on three different matrices, including standard mix, wine, and plasma samples. The automated TMS method showed better reproducibility and higher peak intensity for most of the identified metabolites than the manual derivatisation method. We also validated the automated method using 114 quality control plasma samples. Additionally, we showed that this online method was highly reproducible for most of the metabolites detected and identified (RSD TMS method has been applied to analyse a large number of complex plasma samples. Furthermore, we found that this method was highly applicable for routine metabolite profiling (both targeted and untargeted) in any metabolomics laboratory.

  6. Fully Automated Trimethylsilyl (TMS Derivatisation Protocol for Metabolite Profiling by GC-MS

    Directory of Open Access Journals (Sweden)

    Erica Zarate

    2016-12-01

    Full Text Available Gas Chromatography-Mass Spectrometry (GC-MS has long been used for metabolite profiling of a wide range of biological samples. Many derivatisation protocols are already available and among these, trimethylsilyl (TMS derivatisation is one of the most widely used in metabolomics. However, most TMS methods rely on off-line derivatisation prior to GC-MS analysis. In the case of manual off-line TMS derivatisation, the derivative created is unstable, so reduction in recoveries occurs over time. Thus, derivatisation is carried out in small batches. Here, we present a fully automated TMS derivatisation protocol using robotic autosamplers and we also evaluate a commercial software, Maestro available from Gerstel GmbH. Because of automation, there was no waiting time of derivatised samples on the autosamplers, thus reducing degradation of unstable metabolites. Moreover, this method allowed us to overlap samples and improved throughputs. We compared data obtained from both manual and automated TMS methods performed on three different matrices, including standard mix, wine, and plasma samples. The automated TMS method showed better reproducibility and higher peak intensity for most of the identified metabolites than the manual derivatisation method. We also validated the automated method using 114 quality control plasma samples. Additionally, we showed that this online method was highly reproducible for most of the metabolites detected and identified (RSD < 20 and specifically achieved excellent results for sugars, sugar alcohols, and some organic acids. To the very best of our knowledge, this is the first time that the automated TMS method has been applied to analyse a large number of complex plasma samples. Furthermore, we found that this method was highly applicable for routine metabolite profiling (both targeted and untargeted in any metabolomics laboratory.

  7. Derivatisation/solid-phase microextraction followed by gas chromatography-mass spectrometry for the analysis of phenoxy acid herbicides in aqueous samples

    DEFF Research Database (Denmark)

    Nilsson, Torben; Baglio, Daniela; Galdo-Miguez, Isabel

    1998-01-01

    Different combinations of derivatisation and solid-phase microextraction followed by gas chromatography-mass spectrometry were optimised and evaluated for the analysis of phenoxy acid herbicides in water. The most successful derivatisation approach was aqueous-phase derivatisation with benzyl...

  8. On-cartridge derivatisation using matrix solid phase dispersion for the determination of cyclamate in foods

    International Nuclear Information System (INIS)

    Li, Jianjun; Liu, Yun; Liu, Qianping; Hui, Junfeng; Liu, Yangzi

    2017-01-01

    A novel method for determination of sodium cyclamate in foods was developed. In this method, a syringe was loaded with the homogeneous mixture of the sample, KMnO 4 powder and silica dispersant and used as a matrix solid phase dispersion (MSPD) reactor. As the reactor was infiltrated with small amounts of concentrated HCl, cyclamate was converted to 2-chlorocyclohexanone quickly and effectively within 5 min and determined by HPLC on a reversed-phase column using UV detection at a wavelength of 310 nm. Comparing with the traditional derivatisation in solution, the better clean-up was provided using on-cartridge derivatisation of MSPD, and much time, labor, and expense were saved. The results showed good linearity (r 2  = 0.9998) over the concentration range of 1–500 mg/L. The limit of detection (LOD) and limits of quantification (LOQ) of the cyclamate were 0.3 mg/L and 1 mg/L respectively. The recoveries ranged from 91.6% to 101.3% with the relative standard deviations (RSDs) in the range of 2.5%–4.3%. - Highlights: • A novel method was developed for the determination of cyclamate in foods. • On cartridge derivatisation, using matrix solid phase dispersion, was developed. • A new derivatisation reaction for cyclamate conversion to 2-chlorocyclohexanone was developed. • The method was rapid, simple, inexpensive, effective.

  9. On-cartridge derivatisation using matrix solid phase dispersion for the determination of cyclamate in foods

    Energy Technology Data Exchange (ETDEWEB)

    Li, Jianjun, E-mail: bootan12@126.com [Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Northwest University, Xi' an 710069 (China); National Engineering Research Center for Miniaturized Detection Systems, Xi' an 710069 (China); Liu, Yun [College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi' an 710062 (China); Liu, Qianping [National Engineering Research Center for Miniaturized Detection Systems, Xi' an 710069 (China); Hui, Junfeng [Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Northwest University, Xi' an 710069 (China); Liu, Yangzi [National Engineering Research Center for Miniaturized Detection Systems, Xi' an 710069 (China)

    2017-06-15

    A novel method for determination of sodium cyclamate in foods was developed. In this method, a syringe was loaded with the homogeneous mixture of the sample, KMnO{sub 4} powder and silica dispersant and used as a matrix solid phase dispersion (MSPD) reactor. As the reactor was infiltrated with small amounts of concentrated HCl, cyclamate was converted to 2-chlorocyclohexanone quickly and effectively within 5 min and determined by HPLC on a reversed-phase column using UV detection at a wavelength of 310 nm. Comparing with the traditional derivatisation in solution, the better clean-up was provided using on-cartridge derivatisation of MSPD, and much time, labor, and expense were saved. The results showed good linearity (r{sup 2} = 0.9998) over the concentration range of 1–500 mg/L. The limit of detection (LOD) and limits of quantification (LOQ) of the cyclamate were 0.3 mg/L and 1 mg/L respectively. The recoveries ranged from 91.6% to 101.3% with the relative standard deviations (RSDs) in the range of 2.5%–4.3%. - Highlights: • A novel method was developed for the determination of cyclamate in foods. • On cartridge derivatisation, using matrix solid phase dispersion, was developed. • A new derivatisation reaction for cyclamate conversion to 2-chlorocyclohexanone was developed. • The method was rapid, simple, inexpensive, effective.

  10. Novel iron-cobalt derivatised lithium iron phosphate nanocomposite for lithium ion battery cathode

    CSIR Research Space (South Africa)

    Ikpo, CO

    2013-01-01

    Full Text Available Described herein is the electrochemical study conducted on lithium ion battery cathode material consisting of composite of lithium iron phosphate (LiFePO(sub4), iron-cobalt derivatised carbon nanotubes (FeCo-CNT) and polyaniline (PA) nanomaterials...

  11. Simultaneous analysis of pesticides from different chemical classes by using a derivatisation step and gas chromatography-mass spectrometry.

    Science.gov (United States)

    Raeppel, Caroline; Nief, Marie; Fabritius, Marie; Racault, Lucie; Appenzeller, Brice M; Millet, Maurice

    2011-11-04

    This work presents a new method to analyse simultaneously by GC-MS 31 pesticides from different chemical classes (2,4 D, 2,4 MCPA, alphacypermethrin, bifenthrin, bromoxynil, buprofezin, carbaryl, carbofuran, clopyralid, cyprodinil, deltamethrin dicamba, dichlobenil, dichlorprop, diflufenican, diuron, fenoxaprop, flazasulfuron, fluroxypyr, ioxynil, isoxaben, mecoprop-P, myclobutanil, oryzalin, oxadiazon, picloram, tau-fluvalinate tebuconazole, triclopyr, trifluralin and trinexapac-p-ethyl). This GC-MS method will be applied to the analysis of passive samplers (Tenax(®) tubes and SPME fiber) used for the evaluation of the indoor and outdoor atmospheric contamination by non-agricultural pesticides. The method involves a derivatisation step for thermo-labile or polar pesticides. Different agents were tested and MtBSTFA (N-(t-butyldimethylsilyl)-N-methyltrifluoroacetamide), a sylilation agent producing very specific fragments [M-57], was retained. However, diuron could not be derivatised and the isocyanate product was used for identification and quantification. Pesticides which did not need a derivatisation step were not affected by the presence of the derivatisation agent and they could easily be analysed in mixture with derivatised pesticides. The method can be coupled to a thermal-desorption unit or to SPME extraction for a multiresidue analysis of various pesticides in atmospheric samples. Copyright © 2011 Elsevier B.V. All rights reserved.

  12. A magenta polypyrrole derivatised with Methyl Red azo dye: synthesis and spectroelectrochemical characterisation

    International Nuclear Information System (INIS)

    Almeida, Andresa K.A.; Dias, Jéssica M.M.; Santos, Diego P.; Nogueira, Fred A.R.; Navarro, Marcelo; Tonholo, Josealdo; Lima, Dimas J.P.; Ribeiro, Adriana S.

    2017-01-01

    Highlights: • A pyrrole (Py) derivative functionalised with methyl red (MRPy) was synthesised. • MRPy was polymerised electrochemically in LiClO_4/CH_3CN with BFEE. • Electrochromic properties of PMRPy and PPy doped with methyl red (PPy/MR) were compared. • Colour of the PMRPy changes from magenta to yellow depending on the pH. • PMRPy films might be applicable in optoelectronic devices or in pH sensors. - Abstract: A pyrrole derivative bearing 2-(4-dimethylaminophenylazo)benzoic acid, also known as Methyl Red (MR), was prepared by a simple synthetic route, and electropolymerised onto ITO/glass electrodes in (C_4H_9)_4NBF_4/CH_3CN in presence of boron trifluoride diethyl etherate (BFEE). Films of polypyrrole (PPy) and PPy doped with MR (PPy/MR) were also deposited onto ITO/glass in order to compare their electrochromic properties with the films of PPy derivatised with MR. Cyclic voltammogram of the poly[3-(N-pyrrolyl)propyl 2-(4-dimethylaminophenylazo)benzoate] (PMRPy) film displayed a redox pair with anodic peak potential (Epa) at ca. 0.53 V and cathodic peak potential (Epc) at 0.25 V vs. Ag/Ag"+, corresponding to the polymer p-doping, whilst the PPy/MR film shows capacitive behaviour with a redox pair in the cathodic region (Epa = −0.36 V and Epc = −0.62 V), similar to the PPy film (Epa = −0.10 V, and Epc = −0.15 V), and an anodic wave in the same potential range of that for PMRPy film. The electrochromic properties of the PMRPy film, such as chromatic contrast (Δ%T = 34.2%), switching time (τ = 10 s) and stability (Δ%T = 15% at the 100th cycle), were enhanced relative to the PPy/MR and PPy films. However, the colour of the PMRPy film changed from yellow (-0.8 V) to magenta (E = 1.0 V) in the first cycle and became light magenta at −0.8 V in the subsequent cycles. PMRPy films were also investigated in phosphate buffer solution (PBS, 2.0 ≤ pH ≤ 9.0) and after exposure to HCl vapour, in which the colour varied from magenta at pH = 2.0 to

  13. Determination of butyltins in environmental samples using sodium tetraethylborate derivatisation: characterisation and minimisation of interferences

    International Nuclear Information System (INIS)

    Bowles, Karl C.; Tiltman, Matt D.; Apte, Simon C.; Hales, Leigh T.; Kalman, John

    2004-01-01

    Interferences affecting the determination of butyltin species by sodium tetraethylborate (STEB) derivatisation followed by purge-trap preconcentration were systematically studied using synthetic solutions, natural water samples and sediment extracts. Substances that did not cause interferences included most common cations (apart from those metal ions listed below), anions, metalloids and polar organic compounds. Natural organic matter (NOM) specifically interfered with tributyltin (TBT) due to a mechanism involving partitioning of the butyltin to the hydrophobic portions of the NOM. The metal ions Ag(I) (≥2 μM), Cd(II) (≥2 μM), Cu(II) (≥0.5 μM) interfered predominantly with the determination of monobutyltin (MBT) due to catalytic degradation of the STEB reagent. Pb(II) (≥14 μM) interfered with butyltin determination by an unknown mechanism. Other interferences to the purge-trap method were shown to occur in the presence of chelating agents (e.g. EDTA) or hydrophobic liquids such as diesel fuel. A mixture comprising methanol (MeOH), EDTA and Mn(II) was used to partially mask the effect of interfering NOM and metals. Spike recoveries (mean±S.D. of n=7 different samples) of MBT, dibutyltin (DBT) and TBT in contaminated natural water samples were improved from 70±36,90±11 and 91±24 to 102±10,98±3 and 98±4%, respectively. Spike recoveries (mean±S.D. of n=5 different samples) of MBT, DBT and TBT in aliquots of sediment extracts were improved from 86±17,79±18 and 59±32 to 97±6.2,103±3.6 and 103±5.0%, respectively. The ability to analyse larger aliquots of sediment extracts in the presence of the masking mixture improved the detection limit four-fold if MBT and DBT determination was required and 10-fold if only TBT determination was required

  14. Headspace solid-phase microextraction with 1-pyrenyldiazomethane on-fibre derivatisation for analysis of fluoroacetic acid in biological samples.

    Science.gov (United States)

    Sporkert, Frank; Pragst, Fritz; Hübner, Sandra; Mills, Graham

    2002-05-25

    A new and in part automated headspace solid-phase microextraction method for quantitative determination of the highly toxic rodenticide fluoroacetic acid (FAA) in serum and other biological samples has been developed. FAA and deuterated acetic acid (internal standard) were extracted from acidified samples by a StableFlex divinylbenzene-Carboxen on polydimethylsiloxane fibre. The acids were derivatised on the fibre in-situ with 1-pyrenyldiazomethane and detected using gas chromatography-mass spectrometry with electron impact ionisation and selected ion monitoring. The calibration curve for FAA in serum was linear over the range from 0.02 to 5 microg/ml, with limits of detection and quantification of 0.02 and 0.07 microg/ml, respectively. The method was also tested with spiked whole blood, urine, stomach contents and kidney samples. It was sufficiently reliable, reproducible and sensitive for use in routine forensic toxicology applications.

  15. In situ polyphenyl derivatisation and the effect of thermal decomposition of adsorbed and chemisorbed polyphenyls on the structure of multi-wall carbon nanotubes

    Energy Technology Data Exchange (ETDEWEB)

    Gergely, Andras, E-mail: doohan11@chemres.hu [Department of Surface Modification and Nanostructures, Institute of Nanochemistry and Catalysis, Chemical Research Center of the Hungarian Academy of Sciences, Pusztaszeri ut 59-67, Budapest 1025 (Hungary); Ujszaszy, Kalman [Mass Spectrometry Department, Institute of Structural Chemistry, Pusztaszeri ut 59-67, Chemical Research Center of the Hungarian Academy of Sciences, Budapest 1025 (Hungary); Peltz, Csaba [EGIS Pharmaceuticals PLC, Kereszturi ut 30-38, Budapest 1106 (Hungary); Kiraly, Peter; Tarkanyi, Gabor [NMR Spectroscopy Department, Institute of Structural Chemistry, Chemical Research Center of the Hungarian Academy of Sciences, Pusztaszeri ut 59-67, Budapest 1025 (Hungary); Mihaly, Judith [Department of Biological Nanochemistry, Institute of Nanochemistry and Catalysis, Chemical Research Center of the Hungarian Academy of Sciences, Pusztaszeri ut 59-67, Budapest 1025 (Hungary); Kalman, Erika [Department of Surface Modification and Nanostructures, Institute of Nanochemistry and Catalysis, Chemical Research Center of the Hungarian Academy of Sciences, Pusztaszeri ut 59-67, Budapest 1025 (Hungary)

    2011-05-01

    This study presents the exploitation of an alternative reaction route of deamination of arylamines to perform in situ derivatisation of multi-walled carbon nanotubes (MWCNTs) with polyphenyl (PPh) species of various masses. As a result of consecutive derivatisation, high conversion of PPh grafting of the MWCNTs was realised with the collateral outgrowth of physical modification with adsorbed additional PPhs. Applied derivatisation process exceeds the monolayer coverage related superficial saturation limitations in the overall grafting yield of the nanotubes. Thus, a linear relationship was recognized between the overall quantities of chemisorbed PPhs composed of D{sub 5}-phenylene oligomers and the applied excess of diazonium activated reagents, corresponding to {sup 2}H MAS NMR spectroscopy results. According to mass spectrometry (MS) investigations, uniform thermal decomposition of the chemisorbed PPhs modified MWCNTs was found besides the more intense and altered decomposition characteristic-featured adsorbate-chemisorbate PPhs contained MWCNTs during sequential pyrolysis under inert atmosphere. This is attributed to the pyrolysis provoked isomerisation, decomposition and the formation of adsorbed and chemisorbed PPh moieties. As a result, a mediated and an even more pronounced degradation in the order of graphitic lattice of the MWCNTs were evidenced in the adsorbate-chemisorbate and the chemisorbate PPhs contained samples by FT-Raman spectroscopy and transmission electron microscopy (TEM), respectively. {sup 2}H MAS NMR supplied results of relevant amount of deuterium in the chemisorbate PPh contained sample without traces of aromatic related MS detected volatile products, these allow us to conclude about a thermally stable derivatisation that is interpreted as an endohedral modification of the nanotubes.

  16. Improved sensitivity using liquid chromatography mass spectrometry (LC-MS) for detection of propyl chloroformate derivatised β-N-methylamino-L-alanine (BMAA) in cyanobacteria

    OpenAIRE

    Esterhuizen-Londt, M; Downing, S; Downing, TG

    2011-01-01

    β-N-methylamino-L-alanine (BMAA) is a difficult molecule to detect, primarily due to its presence in low concentrations in complex matrices. This has resulted in contradictory reports on the presence of BMAA in cyanobacteria. We report improved sensitivity of detection using propyl chloroformate derivatisation, liquid chromatographic (LC) separation, and single quadrupole mass spectrometry (MS) detection. Triple quadrupole mass spectrometry (MS/MS) was used to confirm the identity of BMAA in ...

  17. Employing Two-stage Derivatisation and GC-MS to Assay for Cathine and Related Stimulant Alkaloids across the Celastraceae.

    Science.gov (United States)

    Tembrock, Luke R; Broeckling, Corey D; Heuberger, Adam L; Simmons, Mark P; Stermitz, Frank R; Uvarov, Jessica M

    2017-07-01

    Catha edulis (qat, khat, mirra) is a woody plant species that is grown and consumed in East Africa and Yemen for its stimulant alkaloids cathinone, cathine and norephedrine. Two Celastraceae species, in addition to qat, have been noted for their stimulant properties in ethnobotanical literature. Recent phylogenetic reconstructions place four genera in a clade sister to Catha edulis, and these genera are primary candidates to search for cathine and related alkaloids. Determine if cathine or related alkaloids are present in species of Celastraceae other than Catha edulis. Leaf samples from 43 Celastraceae species were extracted in water followed by basification of the aqueous extract and partitioning with methyl-t-butyl ether to provide an alkaloid-enriched fraction. The extract was derivatised in a two-stage process and analysed using GC-MS for the presence of cathine. Related alkaloids and other metabolites in this alkaloid-enriched fraction were tentatively identified. Cathinone, cathine and norephedrine were not detected in any of the 43 Celastraceae species assayed other than Catha edulis. However, the phenylalanine- or tyrosine-derived alkaloid phenylethylamine was identified in five species. Nine species were found to be enriched for numerous sterol- and terpene-like compounds. These results indicate that cathine is unique to Catha edulis, and not the compound responsible for the stimulant properties reported in related Celastraceae species. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  18. Mediation of glycosylated and partially-deglycosylated glucose oxidase of Aspergillus niger by a ferrocene-derivatised detergent.

    Science.gov (United States)

    Fraser, D M; Zakeeruddin, S M; Grätzel, M

    1992-01-30

    A ferrocene-derivatised detergent, (11-ferrocenylundecyl) trimethylammonium bromide (FTMAB), when oxidised to the corresponding ferricinium ion, was found by electrochemical studies to be an effective electron acceptor for reduced glucose oxidase of Aspergillus niger (EC 1.13.4) and thus acts as a electron-transfer mediator between glucose oxidase and a working electrode held at a potential sufficiently positive to reoxidise reduced FTMAB. An increase in mediating activity was produced when FTMAB was present in concentrations above its critical micelle concentration. An 'enzyme electrode' was formed by adsorption of glucose oxidase and FTMAB surfactant on a graphite rod. The electrode functioned as an amperometric biosensor for glucose in phosphate-buffered saline solution. A mixed micelle of glucose oxidase and FTMAB, probably adsorbed on the electrode surface, appears to be advantageous for the amperometric determination of glucose. Additionally, glucose oxidase was treated with alpha-mannosidase. When this partially-deglycosylated glucose oxidase was incorporated in an enzyme electrode, a 100-fold increase in the second-order rate constant (k) for electron transfer between the enzyme and FTMAB was observed, together with increased current densities, with respect to the equivalent values for FTMAB and commercial glucose oxidase. The use of deglycosylated enzymes in biosensors is suggested.

  19. The Determination of Six Ionophore Coccidiostats in Feed by Liquid Chromatography with Postcolumn Derivatisation and Spectrofotometric/Fluorescence Detection

    Directory of Open Access Journals (Sweden)

    Małgorzata Olejnik

    2013-01-01

    Full Text Available The control of levels of anticoccidial feed additives in targeted feeds plays an important role in the assurance of efficiency of animal treatment, prevention of drug resistance, and food safety. The robust and labour-efficient method for the simultaneous determination of six ionophore coccidiostats (lasalocid, maduramicin, monensin, narasin, salinomycin, and semduramicin in targeted feed has been developed. Properly grinded and homogenized feed sample was spiked with internal standard (monesin methyl ester and extracted with methanol. The extract was analysed with reversed phase HPLC without any further purification. The separation of the analytes with conventional C18 and core-shell columns was compared. Lasalocid was analysed with fluorescence detection, whereas other ionophores were detected with UV-Vis detector after derivatisation with vanillin in the presence of sulfuric acid. Fortified samples and targeted feeds at authorized levels were used for method validation. Recovery was in the range of 85–110%, depending on the analyte. The within-laboratory reproducibility did not exceed the target value from Horwitz equation. The results of the proficiency tests (z-scores in the range of −1.0 to 1.9 confirmed the reliability of the developed protocol.

  20. Studies on the analysis of 25-hydroxyvitamin D{sub 3} by isotope-dilution liquid chromatography–tandem mass spectrometry using enzyme-assisted derivatisation

    Energy Technology Data Exchange (ETDEWEB)

    Abdel-Khalik, Jonas, E-mail: J.A.F.A.ABDEL-KHALIK.744116@swansea.ac.uk [Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom); Crick, Peter J. [Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom); Carter, Graham D. [DEQAS, Imperial College Healthcare NHS Trust, Clinical Biochemistry Department, Charing Cross Hospital, Fulham Palace Rd, London W6 8RF (United Kingdom); Makin, Hugh L. [Barts and the Royal London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD (United Kingdom); Wang, Yuqin [Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom); Griffiths, William J., E-mail: w.j.griffiths@swansea.ac.uk [Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP (United Kingdom)

    2014-04-11

    Highlights: • New method for the analysis of 25-hydroxyvitamin D{sub 3} exploiting Girard P derivatisation. • Method also applicable to vitamin D{sub 3}, 1α,25- and 24,25-dihydroxyvitamin D{sub 3}. • By modification of the method 3-epi-25-hydroxyvitamin D{sub 3} can also be analysed. - Abstract: The total serum concentration of 25-hydroxyvitamins D (25-hydroxyvitamin D{sub 3} and 25-hydroxyvitamin D{sub 2}) is currently used as an indicator of vitamins D status. Vitamins D insufficiency is claimed to be associated with multiple diseases, thus accurate and precise reference methods for the quantification of 25-hydroxyvitamins D are needed. Here we present a novel enzyme-assisted derivatisation method for the analysis of vitamins D metabolites in adult serum utilising 25-[26,26,26,27,27,27-{sup 2}H{sub 6}]hydroxyvitamin D{sub 3} as the internal standard. Extraction of 25-hydroxyvitamins D from serum is performed with acetonitrile, which is shown to be more efficient than ethanol. Cholesterol oxidase is used to oxidize the 3β-hydroxy group in the vitamins D metabolites followed by derivatisation of the newly formed 3-oxo group with Girard P reagent. 17β-Hydroxysteroid dehydrogenase type 10 is shown to oxidize selectively the 3α-hydroxy group in the 3α-hydroxy epimer of 25-hydroxyvitamin D{sub 3}. Quantification is achieved by isotope-dilution liquid chromatography–tandem mass spectrometry. Recovery experiments for 25-hydroxyvitamin D{sub 3} performed on adult human serum give recovery of 102–106%. Furthermore in addition to 25-hydroxyvitamin D{sub 3}, 24,25-dihydroxyvitamin D{sub 3} and other uncharacterised dihydroxy metabolites, were detected in adult human serum.

  1. Studies on the analysis of 25-hydroxyvitamin D3 by isotope-dilution liquid chromatography–tandem mass spectrometry using enzyme-assisted derivatisation

    International Nuclear Information System (INIS)

    Abdel-Khalik, Jonas; Crick, Peter J.; Carter, Graham D.; Makin, Hugh L.; Wang, Yuqin; Griffiths, William J.

    2014-01-01

    Highlights: • New method for the analysis of 25-hydroxyvitamin D 3 exploiting Girard P derivatisation. • Method also applicable to vitamin D 3 , 1α,25- and 24,25-dihydroxyvitamin D 3 . • By modification of the method 3-epi-25-hydroxyvitamin D 3 can also be analysed. - Abstract: The total serum concentration of 25-hydroxyvitamins D (25-hydroxyvitamin D 3 and 25-hydroxyvitamin D 2 ) is currently used as an indicator of vitamins D status. Vitamins D insufficiency is claimed to be associated with multiple diseases, thus accurate and precise reference methods for the quantification of 25-hydroxyvitamins D are needed. Here we present a novel enzyme-assisted derivatisation method for the analysis of vitamins D metabolites in adult serum utilising 25-[26,26,26,27,27,27- 2 H 6 ]hydroxyvitamin D 3 as the internal standard. Extraction of 25-hydroxyvitamins D from serum is performed with acetonitrile, which is shown to be more efficient than ethanol. Cholesterol oxidase is used to oxidize the 3β-hydroxy group in the vitamins D metabolites followed by derivatisation of the newly formed 3-oxo group with Girard P reagent. 17β-Hydroxysteroid dehydrogenase type 10 is shown to oxidize selectively the 3α-hydroxy group in the 3α-hydroxy epimer of 25-hydroxyvitamin D 3 . Quantification is achieved by isotope-dilution liquid chromatography–tandem mass spectrometry. Recovery experiments for 25-hydroxyvitamin D 3 performed on adult human serum give recovery of 102–106%. Furthermore in addition to 25-hydroxyvitamin D 3 , 24,25-dihydroxyvitamin D 3 and other uncharacterised dihydroxy metabolites, were detected in adult human serum

  2. Determination of amino acid contents of manketti seeds (Schinziophyton rautanenii) by pre-column derivatisation with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate and RP-HPLC.

    Science.gov (United States)

    Gwatidzo, Luke; Botha, Ben M; McCrindle, Rob I

    2013-12-01

    Defatted kernel flour from manketti seed kernels (Schinziophyton rautanenii) is an underutilised natural product. The plant grows in the wild, on sandy soils little used for agriculture in Southern Africa. The kernels are rich in protein and have a great potential for improving nutrition. The protein content and amino acid profile of manketti seed kernel were studied, using a new analytical method, in order to evaluate the nutritional value. The crude protein content of the press cake and defatted kernel flour was 29.0% and 67.5%, respectively. Leucine and arginine were found to be the most abundant essential and non-essential amino acids, respectively. The seed kernel contained 4.77 g leucine and 12.34 g arginine/100 g of defatted seed kernel flour. Methionine and proline were the least abundant essential and non-essential amino acids to with 0.23 g methionine and 0.36 g proline/100 g of defatted seed kernel flour, respectively. Validation of the pre-column derivatisation procedure with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC) for the determination of amino acids was carried out. The analytical parameters were determined: linearity (0.0025-0.20 mM), accuracy of the derivatisation procedure: 86.7-109.8%, precision (method: 0.72-5.04%, instrumental: 0.14-1.88% and derivatisation: 0.15-2.94% and 0.41-4.32% for intraday and interday, respectively). Limits of detection and quantification were 6.80-157 mg/100 g and 22.7-523 mg/100 g kernel flour, respectively. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. An automated method for the analysis of phenolic acids in plasma based on ion-pairing micro-extraction coupled on-line to gas chromatography/mass spectrometry with in-liner derivatisation

    NARCIS (Netherlands)

    Peters, S.; Kaal, E.; Horsting, I.; Janssen, H.-G.

    2012-01-01

    A new method is presented for the analysis of phenolic acids in plasma based on ion-pairing ‘Micro-extraction in packed sorbent’ (MEPS) coupled on-line to in-liner derivatisation-gas chromatography-mass spectrometry (GC-MS). The ion-pairing reagent served a dual purpose. It was used both to improve

  4. Rapid screening of anabolic steroids in horse urine with ultra-high-performance liquid chromatography/tandem mass spectrometry after chemical derivatisation.

    Science.gov (United States)

    Wong, Colton H F; Leung, David K K; Tang, Francis P W; Wong, Jenny K Y; Yu, Nola H; Wan, Terence S M

    2012-04-06

    Liquid chromatography/mass spectrometry (LC/MS) has been successfully applied to the detection of anabolic steroids in biological samples. However, the sensitive detection of saturated hydroxysteroids, such as androstanediols, by electrospray ionisation (ESI) is difficult because of their poor ability to ionise. In view of this, chemical derivatisation has been used to enhance the detection sensitivity of hydroxysteroids by LC/MS. This paper describes the development of a sensitive ultra-high-performance liquid chromatography/tandem mass spectrometry (UHPLC/MS/MS) method for the screening of anabolic steroids in horse urine by incorporating a chemical derivatisation step, using picolinic acid as the derivatisation reagent. The method involved solid-phase extraction (SPE) of both free and conjugated anabolic steroids in horse urine using a polymer-based SPE cartridge (Abs Elut Nexus). The conjugated steroids in the eluate were hydrolysed by methanolysis and the resulting extract was further cleaned up by liquid-liquid extraction. The resulting free steroids in the extract were derivatised with picolinic acid to form the corresponding picolinoyl esters and analysed by UHPLC/MS/MS in the positive ESI mode with selected-reaction-monitoring. Separation of the targeted steroids was performed on a C18 UHPLC column. The instrument turnaround time was 10.5 min inclusive of post-run equilibration. A total of thirty-three anabolic steroids (including 17β-estradiol, 5(10)-estrene-3β,17α-diol, 5α-estrane-3β,17α-diol, 17α-ethyl-5α-estran-3α,17β-diol, 17α-methyl-5α-androstan-3,17β-diols, androstanediols, nandrolone and testosterone) spiked in negative horse urine at the QC levels (ranging from 0.75 to 30 ng/mL) could be consistently detected. The intra-day and inter-day precisions (% RSD) for the peak area ratios were around 7-51% and around 1-72%, respectively. The intra-day and inter-day precisions (% RSD) for the relative retention times were both less than 1% for

  5. Sensitive monitoring of monoterpene metabolites in human urine using two-step derivatisation and positive chemical ionisation-tandem mass spectrometry

    International Nuclear Information System (INIS)

    Schmidt, Lukas; Belov, Vladimir N.; Göen, Thomas

    2013-01-01

    Highlights: •Sensitive monitoring of 10 metabolites of (R)-limonene, α-pinene, and Δ 3 -carene in human urine samples. •Fast and simple sample preparation and derivatisation procedure using two-step silylation for unreactive tertiary hydroxyl groups. •Synthesis of reference substances and isotopically labelled internal standards of (R)-limonene, α-pinene, and Δ 3 -carene metabolites. •Study on (R)-limonene, α-pinene, and Δ 3 -carene metabolite background exposure of 36 occupationally unexposed volunteers. -- Abstract: A gas chromatographic–positive chemical ionisation-tandem mass spectrometric (GC–PCI-MS/MS) method for the simultaneous determination of 10 oxidative metabolites of the monoterpenoid hydrocarbons α-pinene, (R)-limonene, and Δ 3 -carene ((+)-3-carene) in human urine was developed and tested for the monoterpene biomonitoring of the general population (n = 36). The method involves enzymatic cleavage of the glucuronides followed by solid-supported liquid–liquid extraction and derivatisation using a two-step reaction with N,O-bis(trimethylsilyl)-trifluoroacetamide and N-(trimethylsilyl)imidazole. The method proved to be both sensitive and reliable with detection limits ranging from 0.1 to 0.3 μg L −1 . In contrast to the frequent and distinct quantities of (1S,2S,4R)-limonene-1,2-diol, the (1R,2R,4R)-stereoisomer could not be detected. The expected metabolite of (+)-3-carene, 3-caren-10-ol was not detected in any of the samples. All other metabolites were detected in almost all urine samples. The procedure enables for the first time the analysis of trace levels of a broad spectrum of mono- and bicyclic monoterpenoid metabolites (alcohols, diols, and carboxylic acids) in human urine. This analytical procedure is a powerful tool for population studies as well as for the discovery of human metabolism and toxicokinetics of monoterpenes

  6. Sensitive monitoring of monoterpene metabolites in human urine using two-step derivatisation and positive chemical ionisation-tandem mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Lukas [Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, 91054 Erlangen (Germany); Belov, Vladimir N. [Max Planck Institute for Biophysical Chemistry, Facility for Synthetic Chemistry, Am Fassberg 11, 37077 Göttingen (Germany); Göen, Thomas, E-mail: Thomas.Goeen@ipasum.med.uni-erlangen.de [Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, 91054 Erlangen (Germany)

    2013-09-02

    Highlights: •Sensitive monitoring of 10 metabolites of (R)-limonene, α-pinene, and Δ{sup 3}-carene in human urine samples. •Fast and simple sample preparation and derivatisation procedure using two-step silylation for unreactive tertiary hydroxyl groups. •Synthesis of reference substances and isotopically labelled internal standards of (R)-limonene, α-pinene, and Δ{sup 3}-carene metabolites. •Study on (R)-limonene, α-pinene, and Δ{sup 3}-carene metabolite background exposure of 36 occupationally unexposed volunteers. -- Abstract: A gas chromatographic–positive chemical ionisation-tandem mass spectrometric (GC–PCI-MS/MS) method for the simultaneous determination of 10 oxidative metabolites of the monoterpenoid hydrocarbons α-pinene, (R)-limonene, and Δ{sup 3}-carene ((+)-3-carene) in human urine was developed and tested for the monoterpene biomonitoring of the general population (n = 36). The method involves enzymatic cleavage of the glucuronides followed by solid-supported liquid–liquid extraction and derivatisation using a two-step reaction with N,O-bis(trimethylsilyl)-trifluoroacetamide and N-(trimethylsilyl)imidazole. The method proved to be both sensitive and reliable with detection limits ranging from 0.1 to 0.3 μg L{sup −1}. In contrast to the frequent and distinct quantities of (1S,2S,4R)-limonene-1,2-diol, the (1R,2R,4R)-stereoisomer could not be detected. The expected metabolite of (+)-3-carene, 3-caren-10-ol was not detected in any of the samples. All other metabolites were detected in almost all urine samples. The procedure enables for the first time the analysis of trace levels of a broad spectrum of mono- and bicyclic monoterpenoid metabolites (alcohols, diols, and carboxylic acids) in human urine. This analytical procedure is a powerful tool for population studies as well as for the discovery of human metabolism and toxicokinetics of monoterpenes.

  7. Core-shell magnetite-silica dithiocarbamate-derivatised particles achieve the Water Framework Directive quality criteria for mercury in surface waters.

    Science.gov (United States)

    Lopes, C B; Figueira, P; Tavares, D S; Lin, Z; Daniel-da-Silva, A L; Duarte, A C; Rocha, J; Trindade, T; Pereira, E

    2013-09-01

    The sorption capacity of nanoporous titanosilicate Engelhard titanosilicate number 4 (ETS-4) and silica-coated magnetite particles derivatised with dithiocarbamate groups towards Hg(II) was evaluated and compared in spiked ultra-pure and spiked surface-river water, for different batch factors. In the former, and using a batch factor of 100 m(3)/kg and an initial Hg(II) concentrations matching the maximum allowed concentration in an effluent discharge, both materials achieve Hg(II) uptake efficiencies in excess of 99 % and a residual metal concentration lower than the guideline value for drinking water quality. For the surface-river water and the same initial concentration, the Hg(II) uptake efficiency of magnetite particles is outstanding, achieving the quality criteria established by the Water Framework Directive (concerning Hg concentration in surface waters) using a batch factor of 50 m(3)/kg, while the efficiency of ETS-4 is significantly inferior. The dissimilar sorbents' Hg(II) removal efficiency is attributed to different uptake mechanisms. This study also highlights the importance of assessing the effective capacity of the sorbents under realistic conditions in order to achieve trustable results.

  8. Rapid and sensitive ultrasonic-assisted derivatisation microextraction (UDME) technique for bitter taste-free amino acids (FAA) study by HPLC-FLD.

    Science.gov (United States)

    Chen, Guang; Li, Jun; Sun, Zhiwei; Zhang, Shijuan; Li, Guoliang; Song, Cuihua; Suo, Yourui; You, Jinmao

    2014-01-15

    Amino acids, as the main contributors to taste, are usually found in relatively high levels in bitter foods. In this work, we focused on seeking a rapid, sensitive and simple method to determine FAA for large batches of micro-samples and to explore the relationship between FAA and bitterness. Overall condition optimisation indicated that the new UDME technique offered higher derivatisation yields and extraction efficiencies than traditional methods. Only 35min was needed in the whole operation process. Very low LLOQ (Lower limit of quantification: 0.21-5.43nmol/L) for FAA in twelve bitter foods was obtained, with which BTT (bitter taste thresholds) and CABT (content of FAA at BTT level) were newly determined. The ratio of CABT to BTT increased with decreasing of BTT. This work provided powerful potential for the high-throughput trace analysis of micro-sample and also a methodology to study the relationship between the chemical constituents and the taste. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Simultaneous derivatisation and preconcentration of parabens in food and other matrices by isobutyl chloroformate and dispersive liquid-liquid microextraction followed by gas chromatographic analysis.

    Science.gov (United States)

    Jain, Rajeev; Mudiam, Mohana Krishna Reddy; Chauhan, Abhishek; Ch, Ratnasekhar; Murthy, R C; Khan, Haider A

    2013-11-01

    A simple, rapid and economical method has been proposed for the quantitative determination of parabens (methyl, ethyl, propyl and butyl paraben) in different samples (food, cosmetics and water) based on isobutyl chloroformate (IBCF) derivatisation and preconcentration using dispersive liquid-liquid microextraction in single step. Under optimum conditions, solid samples were extracted with ethanol (disperser solvent) and 200 μL of this extract along with 50 μL of chloroform (extraction solvent) and 10 μL of IBCF was rapidly injected into 2 mL of ultra-pure water containing 150 μL of pyridine to induce formation of a cloudy state. After centrifugation, 1 μL of the sedimented phase was analysed using gas chromatograph-flame ionisation detector (GC-FID) and the peaks were confirmed using gas chromatograph-positive chemical ionisation-mass spectrometer (GC-PCI-MS). Method was found to be linear over the range of 0.1-10 μg mL(-1) with square of correlation coefficient (R(2)) in the range of 0.9913-0.9992. Limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.029-0.102 μg mL(-1) and 0.095-0.336 μg mL(-1) with a signal to noise ratio of 3:1 and 10:1, respectively. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Rapid determination of glyphosate in cereal samples by means of pre-column derivatisation with 9-fluorenylmethyl chloroformate and coupled-column liquid chromatography with fluorescence detection.

    Science.gov (United States)

    Hogendoorn, E A; Ossendrijver, F M; Dijkman, E; Baumann, R A

    1999-02-12

    A rapid procedure for the determination of glyphosate in cereals has been developed. Convenient sample pretreatment is carried out by (i) a overnight standing extraction of 1.0 g homogenized sample with 20 ml of water, (ii) centrifugation of the samples, (iii) a passing of 2.5 ml of the clear layer through a 100 mg C18 solid-phase extraction cartridge and (iv) collection of the last 1.5 ml of the eluent into a calibrated tube. For the instrumental analysis, the efficient approach developed earlier for environmental water samples [J.V. Sancho, F. Hernández, F.J. LUpez, E.A. Hogendoorn, E. Dijkman, P. van Zoonen, J. Chromatogr. A, 737 (1996) 75] was successfully adopted for the determination of glyphosate in the obtained cereal extracts. The procedure includes a 15 min derivatisation step of the analyte with 9-fluorenylmethyl chloroformate and a 16 times dilution step prior to instrumental analysis employing coupled-column LC with fluorescence detection. The developed procedure has a sample throughput of more than 25 samples per day and a limit of quantification of 0.5 mg/kg. The method was validated by analyzing freshly spiked cereal samples and samples with aged residues at levels between 1.0 and 10 mg/kg. The overall recovery of the freshly spiked samples was 86% (n = 10) with a repeatability of 6.5% and a reproducibility of 9.5%. For samples with aged residues recoveries performed at different time intervals (range 80-150 days) did not differ significantly; the overall recovery (n = 10) was 74% with a repeatability and reproducibility of 14 and 20%, respectively.

  11. Simultaneous determination of morphine, codeine and 6-acetyl morphine in human urine and blood samples using direct aqueous derivatisation: validation and application to real cases.

    Science.gov (United States)

    Chericoni, S; Stefanelli, F; Iannella, V; Giusiani, M

    2014-02-15

    Opiates play a relevant role in forensic toxicology and their assay in urine or blood is usually performed for example in workplace drug-testing or toxicological investigation of drug impaired driving. The present work describes two new methods for detecting morphine, codeine and 6-monoacethyl morphine in human urine or blood using a single step derivatisation in aqueous phase. Propyl chloroformate is used as the dramatizing agent followed by liquid-liquid extraction and gas-chromatography-mass spectroscopy to detect the derivatives. The methods have been validated both for hydrolysed and unhydrolysed urine. For hydrolysed urine, the LOD and LOQ were 2.5ng/ml and 8.5ng/ml for codeine, and 5.2ng/ml and 15.1ng/ml for morphine, respectively. For unhydrolysed urine, the LOD and LOQ were 3.0ng/ml and 10.1ng/ml for codeine, 2.7ng/ml and 8.1ng/ml for morphine, 0.8ng/ml and 1.5ng/ml for 6-monoacetyl morphine, respectively. In blood, the LOD and LOQ were 0.44ng/ml and 1.46ng/ml for codeine, 0.29ng/ml and 0.98ng/ml for morphine, 0.15ng/ml and 0.51ng/ml for 6-monoacetyl morphine, respectively. The validated methods have been applied to 50 urine samples and 40 blood samples (both positive and negative) and they can be used in routine analyses. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. Breaking the sensitivity limitations of cytochrome P450 oxidation product: dansyl chloride derivatisation of 4-OH mephenytoin, a CYP2C19 metabolite and its application to in vitro CYP inhibition assay.

    Science.gov (United States)

    Vijayabhaskar, V; Srivastava, Pratima; Rajagopal, Sriram

    2015-05-01

    A rapid selective and sensitive liquid chromatography/tandem mass spectrometry (LC-MS/MS) method was developed for the quantitative determination of derivatised cytochrome P450-2C19 oxidation product (dansyl-4-OH mephenytoin) and its underivatised form (4-OH mephenytoin). Samples were anaysed on C18 column (Waters Xbridge, 50 mm×4.6 mm, 3.5 μm particle size) with the mobile phase consisting of 0.1% formic acid in water and 0.1% formic acid in acetonitrile. A gradient method with a short run time of 2.5 min and 3.5 min was developed for the analysis of dansyl-4-OH mephenytoin and 4-OH mephenytoin, respectively. The standard curve was linear (r(2)=0.9972 for 4-OH mephenytoin; r(2)=0.9946 for dansyl-4-OH mephenytoin) over the concentration range of 0.16 to 40 ng/mL for both derivatised and underivatised forms. The CV (%) and relative error (RE) for inter and intraassay at three QC levels for dansyl-4-OH mephenytoin was 0.97-5.85% and -9.80 to 2.51%, respectively. Whereas, for 4-OH mephenytoin the CV (%) and RE (%) at three QC levels was 0.82-3.47% and -6.69 to -0.01%, respectively. The developed method was validated for various parameters such as linearity, precision & accuracy, extraction recovery, matrix effect, autosampler stability and was proved to be consistent across three QC levels with overall CV (%) less than 15. Dansylation helped in increasing the sensitivity of hydroxy mephenytoin by 100-200 fold. Given the simplicity involved in derivatisation process, we believe that this novel methodology will change the current approaches used for the enhancing the detection sensitivity of 4-OH mephenytoin. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. A fast, reliable, ultra high performance liquid chromatography method for the simultaneous determination of amino acids, biogenic amines and ammonium ions in cheese, using diethyl ethoxymethylenemalonate as a derivatising agent.

    Science.gov (United States)

    Redruello, Begoña; Ladero, Victor; Cuesta, Isabel; Álvarez-Buylla, Jorge R; Martín, María Cruz; Fernández, María; Alvarez, Miguel A

    2013-08-15

    Derivatisation treatment with diethyl ethoxymethylenemalonate followed by ultra-HPLC allowed the simultaneous quantification of 22 amino acids, 7 biogenic amines and ammonium ions in cheese samples in under 10 min. This is the fastest elution time ever reported for such a resolution. The proposed method shows good linearity (R(2)>0.995) and sensitivity (detection limit 0.08-3.91 μM; quantification limit <13.02 μM). Intra- and inter-day repeatability ranged from 0.35% to 1.25% and from 0.85% to 5.2%, respectively. No significant effect of the cheese matrix was observed. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. A reliable compound-specific nitrogen isotope analysis of amino acids by GC-C-IRMS following derivatisation into N-pivaloyl-iso-propyl (NPIP)esters for high-resolution food webs estimation.

    Science.gov (United States)

    Zhang, Zhongyi; Tian, Jing; Xiao, Hongwei; Zheng, Nengjian; Gao, Xiaofei; Zhu, Renguo; Xiao, Huayun

    2016-10-15

    The signatures of natural stable nitrogen isotopic composition (δ(15)N) of individual amino acid (AA) have been confirmed to be a potentially effective tool for elucidating nitrogen cycling and trophic position of various organisms in food webs. In the present study, a two-stage derivatisation approach of esterification followed by acylation was evaluated. The biological samples underwent acid hydrolysis and the released individual AA was derivatived into corresponding N-pivaloyl-isopropyl (NPIP) esters for nitrogen isotopic analysis in gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS). Usually, 13 individual AA derivatives were separated with fine baseline resolution based on a nonpolar gas chromatography column (DB-5ms). The minimum sample amount required under the presented conditions is larger than 20ngN on column in order to accurately determine the δ(15)N values. The δ(15)N values determined by GC-C-IRMS with a precision of better than 1‰, were within 1‰ after empirical correction compared to the corresponding measured by element analysis (EA)-IRMS. Bland-Altman plot showed highly consistency of the δ(15)N values determined by the two measurement techniques. Cation-exchange chromatography was applied to remove interfering fraction from the extracts of plant and animal samples and without nitrogen isotope fractionation during the treatment procedure. Moreover, this approach was carried out to estimate the trophic level of various natural organisms in a natural lake environment. Results highly proved that the trophic level estimated via the presented AA method well reflected the actual food web structure in natural environments. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Single Pot Selective Hydrogenation of Furfural to 2-Methylfuran Over Carbon Supported Iridium Catalysts

    KAUST Repository

    Date, Nandan S; Hengne, Amol Mahalingappa; Huang, Kuo-Wei; Chikate, Rajeev C.; Rode, C. V.

    2018-01-01

    Various iridium supported carbon catalysts were prepared and screened for direct hydrogenation of furfural (FFR) to 2-methyl furan (2-MF). Amongest these, 5% Ir/C showed excellent results with complete FFR conversion and highest selectivity of 95% to 2-MF at very low H2 pressure of 100 psig. Metallic (Iro) and oxide ( IrO2) phases of Ir catalyzed first step hydrogenation involving FFR to FAL and subsequent hydrogenation to 2-MF,respecively. This was confirmed by XPS analysis and some controlled experiments. At low temperature of 140 oC, almost equal selectivities of FAL (42%) and 2-MF (43%) were observed, while higher temperature (220oC) favored selective hydrodeoxygenation. At optimized temperature, 2-MF formed selectively while higher pressure and higher catalyst loading favored ring hydrogenation of furfural rather than side chain hydrogenation. With combination of several control experimental results and detailed catalyst characterization, a plausible reaction pathway has been proposed for selective formation of 2-MF. The selectivity to various other products in FFR hydrogenation can be manipulated by tailoring the reaction conditions over the same catalyst.

  16. Single Pot Selective Hydrogenation of Furfural to 2-Methylfuran Over Carbon Supported Iridium Catalysts

    KAUST Repository

    Date, Nandan S

    2018-03-20

    Various iridium supported carbon catalysts were prepared and screened for direct hydrogenation of furfural (FFR) to 2-methyl furan (2-MF). Amongest these, 5% Ir/C showed excellent results with complete FFR conversion and highest selectivity of 95% to 2-MF at very low H2 pressure of 100 psig. Metallic (Iro) and oxide ( IrO2) phases of Ir catalyzed first step hydrogenation involving FFR to FAL and subsequent hydrogenation to 2-MF,respecively. This was confirmed by XPS analysis and some controlled experiments. At low temperature of 140 oC, almost equal selectivities of FAL (42%) and 2-MF (43%) were observed, while higher temperature (220oC) favored selective hydrodeoxygenation. At optimized temperature, 2-MF formed selectively while higher pressure and higher catalyst loading favored ring hydrogenation of furfural rather than side chain hydrogenation. With combination of several control experimental results and detailed catalyst characterization, a plausible reaction pathway has been proposed for selective formation of 2-MF. The selectivity to various other products in FFR hydrogenation can be manipulated by tailoring the reaction conditions over the same catalyst.

  17. Global Strategy

    DEFF Research Database (Denmark)

    Li, Peter Ping

    2013-01-01

    Global strategy differs from domestic strategy in terms of content and process as well as context and structure. The content of global strategy can contain five key elements, while the process of global strategy can have six major stages. These are expounded below. Global strategy is influenced...... by rich and complementary local contexts with diverse resource pools and game rules at the national level to form a broad ecosystem at the global level. Further, global strategy dictates the interaction or balance between different entry strategies at the levels of internal and external networks....

  18. Single pot synthesized gold nanoparticles using Hippophae rhamnoides leaf and berry extract showed shape-dependent differential nanobiotechnological applications.

    Science.gov (United States)

    Sharma, Bhavana; Deswal, Renu

    2018-04-04

    A facile one-pot green synthesis of gold nanoparticles (AuNPs) with different geometries was achieved using an underutilized Himalayan bioresource Hippophae rhamnoides. Aqueous leaf (LE) and berry extracts (BE) showed rapid synthesis of monodispersed spherical LEAuNPs (27 ± 3.2 nm) and anisotropic BEAuNPs (55 ± 4.5 nm) within 2 and 15 min, respectively. The Fourier-transform infrared (FTIR) spectroscopy showed involvement of polyphenolics/flavonoids in AuNPs reduction. LE AuNPs (IC 50 49 µg) exhibited higher antioxidant potential than BE AuNPs (IC 50 57 µg). Both BE nanotriangles and LE nanospheres exhibited cytotoxicity against Jurkat cell lines. These nanocatalysts also exhibited effective (80-99%) reductive degradation of structurally different carcinogenic azo dyes. Kinetic studies revealed that BE nanotriangles exhibited higher catalytic efficiency (14-67%) than LE nanospheres suggesting shape-dependent regulation of biological activities. The gas chromatography-mass spectrometry (GC-MS) analysis confirmed conversion of toxic methyl orange dye to non-toxic intermediates. Probable degradation mechanism involving adsorption and catalytic reduction of azo bonds was proposed. The present synthesis protocol provided a facile and energy saving procedure for rapid synthesis of highly stable nanoparticles with significant antioxidant and anticancer potential. This is the first report of H. rhamnoides-mediated green synthesis of multipurpose AuNPs as antioxidant, anticancer and nanocatalytic agents for treatment of dye contaminated waste water and future therapeutic applications.

  19. Appropriate strategies.

    Science.gov (United States)

    Halty, M

    1979-01-01

    Technology strategies are concerned with the production, distribution, and consumption of technology. Observation of less developed countries (LDCs) and international organizations shows that little attention is given to the development of a technology strategy. LDCs need to formulate a strategy of self-reliant technological development for the next decade. They should no longer be content to stand in a technologically dependent relationship to the developed countries. Such strategies must balance the ratio between investment in indigenous technologies and expenditure for foreign technology. The strategies change according to the level of industrialization achieved. The following considerations come into development of technology strategies: 1) determination of an appropriate balance among the accumulation, consumption, and distribution of technology; 2) the amount and level of government support; and 3) the balance between depth and breadth of technology to be encouraged.

  20. Environmental strategy

    DEFF Research Database (Denmark)

    Zabkar, Vesna; Cater, Tomaz; Bajde, Domen

    2013-01-01

    perspective, appropriate environmental strategies in compliance with environmental requirements aim at building competitive advantages through sustainable development. There is no universal “green” strategy that would be appropriate for each company, regardless of its market requirements and competitive......Environmental issues and the inclusion of environmental strategies in strategic thinking is an interesting subject of investigation. In general, managerial practices organized along ecologically sound principles contribute to a more environmentally sustainable global economy. From the managerial...

  1. Evaluation Strategy

    DEFF Research Database (Denmark)

    Coto Chotto, Mayela; Wentzer, Helle; Dirckinck-Holmfeld, Lone

    2009-01-01

    The paper presents an evaluation strategy based on deliberate ideals and principles of dialogue design. The evaluation strategy is based on experiential phenomenology taking the point of departure for design and evaluation processes in the experienced practitioners themselves. The article present...... the evaluation strategy and methodology of a research project Making Online Path to Enter new Markets, MOPEM. It is an EU-research project with partners from different Educational Institutions of Technology and Business in five European Countries.......The paper presents an evaluation strategy based on deliberate ideals and principles of dialogue design. The evaluation strategy is based on experiential phenomenology taking the point of departure for design and evaluation processes in the experienced practitioners themselves. The article presents...

  2. Safety strategy

    International Nuclear Information System (INIS)

    Schultheiss, G.F.

    1980-01-01

    The basis for safety strategy in nuclear industry and especially nuclear power plants is the prevention of radioactivity release inside or outside of the technical installation. Therefore either technical or administrative measures are combined to a general strategy concept. This introduction will explain in more detail the following topics: - basic principles of safety - lines of assurance (LOA) - defense in depth - deterministic and probabilistic methods. This presentation is seen as an introduction to the more detailed discussion following in this course, nevertheless some selected examples will be used to illustrate the aspects of safety strategy development although they might be repeated later on. (orig.)

  3. Export strategy

    DEFF Research Database (Denmark)

    Knudsen, Thorbjørn; Koed Madsen, Tage

    2002-01-01

    It is argued here that traditional export strategy research (encompassing the study of internationalization processes and export performance) is characterized by weak theoretical foundations and could benefit from a reorientation towards a dynamic capabilities perspective (DCP). We seek to draw...... on insights from DCP in order to devise a theoretical basis that could enrich export strategy research. Although our development of DCP insights builds on previous work, it also adds a crucial distinction between knowledge stocks and informational architecture. Changes in architecture are of greater...... importance. Following this elaboration of the dynamic capabilities perspective, we outline some implications and guidelines for future export strategy research....

  4. CSR STRATEGIES

    OpenAIRE

    LAURENTIU BARANGA; ION STEGAROIU

    2011-01-01

    Corporate Social Responsibility (CSR) has got three components: economic responsibility of shareholders, corporate environmental responsibility, corporate responsibility of the society. Each component of the CSR has its own features, according to which adequate individual behaviour is established. Knowing these features is very important in CSR strategy development.

  5. DOT strategies versus orbiter strategies

    NARCIS (Netherlands)

    Rutten, R.J.

    2001-01-01

    The Dutch Open Telescope is a high-resolution solar imager coming on-line at La Palma. The definition of the DOT science niche, strategies, and requirements resemble Solar Orbiter considerations and deliberations. I discuss the latter in the light of the former, and claim that multi-line observation

  6. Study Strategies

    DEFF Research Database (Denmark)

    Nielsen, Camilla Kirketerp; Noer, Vibeke Røn

    and theory forms the basis of the research. Veterinary students have been followed through alternating learning contexts referring to both the scholastic academic classrooms and workplaces in commercial pig herds as well as to group work and game-based situations in a mandatory master course - ”the pig...... as a student´ and the process of professionalization. By maintaining the position of focusing upon the education as a situated and formative trajectory, the comparative analysis shows how students in profession-oriented educational settings manage the challenges of education and use study strategies......ID: 1277 / 22 SES 06 B: 2 22. Research in Higher Education Format of Presentation: Paper Alternative EERA Network: 19. Ethnography Topics: NW 22: Teaching, learning and assessment in higher education Keywords: Profession-oriented learning, study strategies, professionalisation processes...

  7. Arbitrage strategy

    OpenAIRE

    Kardaras, Constantinos

    2010-01-01

    An arbitrage strategy allows a financial agent to make certain profit out of nothing, i.e., out of zero initial investment. This has to be disallowed on economic basis if the market is in equilibrium state, as opportunities for riskless profit would result in an instantaneous movement of prices of certain financial instruments. The principle of not allowing for arbitrage opportunities in financial markets has far-reaching consequences, most notably the option-pricing and hedging formulas in c...

  8. Marketing Strategy

    OpenAIRE

    Andrýsková, Hana

    2013-01-01

    The aim of this thesis is to examine current marketing efforts of AARON - the leading seller of digital cameras. I will analyze current marketing tools and suggest improvements in efficiency and effectiveness of these tools. Marketing strategy is a method of managing and coordinating efforts in marketing field so that the goals can be reached. The aim is to increase sales, turnover, revenues, profits, drive out competition and also to build up a corporate image and corporate culture. I will a...

  9. Transfusion strategy

    DEFF Research Database (Denmark)

    Jakobsen, Carl-Johan

    2014-01-01

    Blood transfusion is associated with increased morbidity and mortality and numerous reports have emphasised the need for reduction. Following this there is increased attention to the concept of patient blood management. However, bleeding is relatively common following cardiac surgery and is furth....... In conclusion the evidence supports that each institution establishes its own patient blood management strategy to both conserve blood products and maximise outcome.......Blood transfusion is associated with increased morbidity and mortality and numerous reports have emphasised the need for reduction. Following this there is increased attention to the concept of patient blood management. However, bleeding is relatively common following cardiac surgery and is further...

  10. NATO strategy

    International Nuclear Information System (INIS)

    Tarr, D.W.

    1988-01-01

    Nuclear weapons are for NATO both the primary instrument for deterring a nuclear attack and the fall-back option if, in the event of a conventional assault, NATO's non-nuclear defence forces cannot hold. The dilemma of depending upon potentially self-destructive nuclear responses if deterrence fails and defence falters has always haunted NATO strategy, but after the Soviets achieved nuclear parity with the United States, this dilemma became more intensely perceived. Now the credibility, viability, acceptability, sensibility and morality of nuclear weapons for deterrence and defence are increasingly at issue. As a result, an increasing variety of non-nuclear (conventional) alternatives are being advanced to replace or supplement nuclear deterrence for the Alliance. The thrust of the author of this paper remarks is to attempt to apply the definitions, requirements, and other key conceptual distinctions of nuclear deterrence found in the body of western strategic literature to three categories of non-nuclear alternatives currently in vogue: strengthened conventional forces; deployment of new, high-technology non-nuclear weapons; and adoption of an offensive manoeuvre strategy. Let me, therefore, begin by listing the basic definitions, concepts and apparent requirements of deterrence which the deterrence theory literature offers

  11. Implementation Strategy

    Science.gov (United States)

    1983-01-01

    Meeting the identified needs of Earth science requires approaching EOS as an information system and not simply as one or more satellites with instruments. Six elements of strategy are outlined as follows: implementation of the individual discipline missions as currently planned; use of sustained observational capabilities offered by operational satellites without waiting for the launch of new mission; put first priority on the data system; deploy an Advanced Data Collection and Location System; put a substantial new observing capability in a low Earth orbit in such a way as to provide for sustained measurements; and group instruments to exploit their capabilities for synergism; maximize the scientific utility of the mission; and minimize the costs of implementation where possible.

  12. Prodrug Strategy in Drug Development

    Directory of Open Access Journals (Sweden)

    Hajnal Kelemen

    2016-09-01

    Full Text Available Prodrugs are chemically modified derivatives introduced in therapy due to their advantageous physico-chemical properties (greater stability, improved solubility, increased permeability, used in inactive form. Biological effect is exerted by the active derivatives formed in organism through chemical transformation (biotransformation. Currently, 10% of pharmaceutical products are used as prodrugs, nearly half of them being converted to active form by hydrolysis, mainly by ester hydrolysis. The use of prodrugs aims to improve the bioavailability of compounds in order to resolve some unfavorable characteristics and to reduce first-pass metabolism. Other objectives are to increase drug absorption, to extend duration of action or to achieve a better tissue/organ selective transport in case of non-oral drug delivery forms. Prodrugs can be characterized by chemical structure, activation mechanism or through the presence of certain functional groups suitable for their preparation. Currently we distinguish in therapy traditional prodrugs prepared by chemical derivatisation, bioprecursors and targeted delivery systems. The present article is a review regarding the introduction and applications of prodrug design in various areas of drug development.

  13. Interactive Control System, Intended Strategy, Implemented Strategy dan Emergent Strategy

    Directory of Open Access Journals (Sweden)

    Tubagus Ismail

    2012-09-01

    Full Text Available The purpose of this study was to examine the relationship between management control system (MCS and strategy formation processes, namely: intended strategy, emergent strategy and impelemented strategy. The focus of MCS in this study was interactive control system. The study was based on Structural Equation Modeling (SEM as its multivariate analyses instrument. The samples were upper middle managers of manufacturing company in Banten Province, DKI Jakarta Province and West Java Province. AMOS Software 16 program is used as an additional instrument to resolve the problem in SEM modeling. The study found that interactive control system brought a positive and significant influence on Intended strategy; interactive control system brought a positive and significant influence on implemented strategy; interactive control system brought a positive and significant influence on emergent strategy. The limitation of this study is that our empirical model only used one way relationship between the process of strategy formation and interactive control system.

  14. Interactive Control System, Intended Strategy, Implemented Strategy dan Emergent Strategy

    OpenAIRE

    Tubagus Ismail; Darjat Sudrajat

    2012-01-01

    The purpose of this study was to examine the relationship between management control system (MCS) and strategy formation processes, namely: intended strategy, emergent strategy and impelemented strategy. The focus of MCS in this study was interactive control system. The study was based on Structural Equation Modeling (SEM) as its multivariate analyses instrument. The samples were upper middle managers of manufacturing company in Banten Province, DKI Jakarta Province and West Java Province. AM...

  15. Analytical strategies for phosphoproteomics

    DEFF Research Database (Denmark)

    Thingholm, Tine E; Jensen, Ole N; Larsen, Martin R

    2009-01-01

    sensitive and specific strategies. Today, most phosphoproteomic studies are conducted by mass spectrometric strategies in combination with phospho-specific enrichment methods. This review presents an overview of different analytical strategies for the characterization of phosphoproteins. Emphasis...

  16. Strategy Development in Organisations

    DEFF Research Database (Denmark)

    Sørensen, Lene

    1999-01-01

    There exist certain ambiguities with the converging fields of information technology and organisational strategy development. The term "IT strategy" has evolved and reflects in some respects this confusion. This paper discusses some of the ambiguities and difficulties of the term "IT strategy......" as used in practice and literature. Emphasis is put on how the term is related to the problem, the organisation, the strategy process and the practical way of methodologically developing the strategy. Finally, alternative strategy developing perspectives are presented....

  17. Strategy and space

    DEFF Research Database (Denmark)

    Jensen, Per Anker

    2011-01-01

    in different periods and how these strategies can be related to the general conditions of the corporation. The strategic uncertainty of the corporation is investigated as a main determining factor for changes in space strategy based on theories of the relations between strategy and place. These theories......The article is based on results from a research project on space strategies and building values, which included a major case study of the development of facilities for the Danish Broadcasting Corporation over time. The focus is to identify, how different space strategies have been implemented...... include that corporations follows one of the three generic space strategies: Incrementalism, standardization, and value-based strategy. Among the conclusion are, that the space strategies mostly changes between incremental and value-based strategies, but one period of standardization was identified...

  18. De Nederlandse cybersecurity strategie

    NARCIS (Netherlands)

    Luiijf, H.A.M.

    2011-01-01

    Recent werd de Nederlandse 'Nationale Cybersecurity Strategie: Slagkracht door samenwerking' openbaar gemaakt. Wat zijn de hoofdpunten van deze strategie en wat betekend dat voor de burgers, bedrijven, overheid, afnemers of leveranciers van informatie- en communicatie technologie?

  19. Radioactive Waste Management Strategy

    International Nuclear Information System (INIS)

    2002-01-01

    This strategy defines methods and means how collect, transport and bury radioactive waste safely. It includes low level radiation waste and high level radiation waste. In the strategy are foreseen main principles and ways of storage radioactive waste

  20. National Privacy Research Strategy

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — On July 1, NITRD released the National Privacy Research Strategy. Research agencies across government participated in the development of the strategy, reviewing...

  1. US Strategy for Cyberspace

    National Research Council Canada - National Science Library

    Veazie, Arnold

    2003-01-01

    .... This strategic research paper analyzes the President's National Strategy to Secure Cyberspace to determine whether it effectively provides solutions for securing cyberspace. It concludes by proposing an alternative strategy for securing cyberspace.

  2. POSITIONING STRATEGIES DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Shakhshir Ghassan

    2014-07-01

    Full Text Available The positioning strategy has suffered serious changes in the last few decades, being influenced by the rapid development of competition and the growing focus on specific traits belonging to the market, to the consumer or to the product. The purpose of this paper is to present the developments of theoretical positioning strategies and the orientation from more simple, product oriented strategies, to ones more oriented towards the client and with a briefer period of time. The world is moving in a much faster pace than in the past, thanks to communication development so companies are obliged to adopt more specific strategies in order for them to be effective. This essay represents a literary review presenting a documentary research within the scientific articles and strategy and positioning books. The paper begins with the analysis of company strategies and the marketing strategies in general. The first author to group the product positioning strategies is Porter with his three generic strategies. Following the development of brands and because of the lack of competitiveness in the simple generic positioning strategies, this paper has also presented the newer positioning strategies proposed by Kotler, Treacy & Wiersema, and also more complex ones such as Bowman's Strategy Clock and Blankson and Kalafatis positioning strategy based on the type of the consumer. The fast expansion of local brands in all categories has led to mistakes in positioning strategies, categories also presented in the current essay. The results of this study show that new positioning strategies are more and more based on the consumer and market segments and on the product specification - which have also evolved in the last decades. Adaptability to fast changes in the competitive market will represent the future positioning strategies.

  3. Digital Content Strategies

    OpenAIRE

    Halbheer, Daniel; Stahl, Florian; Koenigsberg, Oded; Lehmann, Donald R

    2013-01-01

    This paper studies content strategies for online publishers of digital information goods. It examines sampling strategies and compares their performance to paid content and free content strategies. A sampling strategy, where some of the content is offered for free and consumers are charged for access to the rest, is known as a "metered model" in the newspaper industry. We analyze optimal decisions concerning the size of the sample and the price of the paid content when sampling serves the dua...

  4. Manufacturing knowledge management strategy

    OpenAIRE

    Shaw , Duncan; Edwards , John

    2006-01-01

    Abstract The study sought to understand the components of knowledge management strategy from the perspective of staff in UK manufacturing organisations. To analyse this topic we took an empirical approach and collaborated with two manufacturing organisations. Our main finding centres on the key components of a knowledge management strategy, and the relationships between it and manufacturing strategy and corporate strategy. Other findings include: the nature of knowledge in manufact...

  5. Strategy Instruction in Mathematics.

    Science.gov (United States)

    Goldman, Susan R.

    1989-01-01

    Experiments in strategy instruction for mathematics have been conducted using three models (direct instruction, self-instruction, and guided learning) applied to the tasks of computation and word problem solving. Results have implications for effective strategy instruction for learning disabled students. It is recommended that strategy instruction…

  6. Online Strategy Games.

    Science.gov (United States)

    Dye, Bryan

    2002-01-01

    A strategy game is an online interactive game that requires thinking in order to be played at its best and whose winning strategy is not obvious. Provides information on strategy games that are written in Java or JavaScript and freely available on the web. (KHR)

  7. Backbone amide linker strategy

    DEFF Research Database (Denmark)

    Shelton, Anne Pernille Tofteng; Jensen, Knud Jørgen

    2013-01-01

    In the backbone amide linker (BAL) strategy, the peptide is anchored not at the C-terminus but through a backbone amide, which leaves the C-terminal available for various modifications. This is thus a very general strategy for the introduction of C-terminal modifications. The BAL strategy...

  8. Strategies Against Poverty.

    Science.gov (United States)

    Riessman, Frank

    The major antipoverty strategies of the 1960's are analyzed--the conflict model of Alinsky, the welfare crisis approach of Cloward and Piven, and the new careers viewpoint of Riessman and Pearl. The latter strategy is said to have a greater "multiplier effect" on poverty than other approaches. Discussed are such specific strategies in…

  9. Elevator Control Strategies

    OpenAIRE

    Ceder, Frederick; Nordin, Alexandra

    2013-01-01

    The purpose of this essay is to investigate if it is eective to switch strategies for elevators during one day in an oce building. This essay describes some of the strategies in use today, followed by a comparison and analysis of two of the strategies described. We have also implemented optimizations to one of these strategies. From our test results we can conclude that our optimized strategy worked and produced better results on average waiting time and total traveling time than the two stra...

  10. Contemporary evolution strategies

    CERN Document Server

    Bäck, Thomas; Krause, Peter

    2013-01-01

    Evolution strategies have more than 50 years of history in the field of evolutionary computation. Since the early 1990s, many algorithmic variations of evolution strategies have been developed, characterized by the fact that they use the so-called derandomization concept for strategy parameter adaptation. Most importantly, the covariance matrix adaptation strategy (CMA-ES) and its successors are the key representatives of this group of contemporary evolution strategies. This book provides an overview of the key algorithm developments between 1990 and 2012, including brief descriptions of the a

  11. Creativity and Strategy Development

    DEFF Research Database (Denmark)

    Sørensen, Lene Tolstrup; Vidal, Rene Victor Valqui

    This paper focus on how creative thinking, processes and methods can support the strategy development and planning process in organisations. First, several fundamental concepts related to both strategy development and planning are stipulated. In addition, the concept of living organisation...... will be discussed as well as the interaction between strategy and creativity. Then, methodological ideas to support the strategy making process are presented enhancing the use of creative methods and tools. Finally, a case study related to the development of a strategy for organisational development using...... creativity tools is discussed....

  12. Strategies in PRholog

    Directory of Open Access Journals (Sweden)

    Besik Dundua

    2010-01-01

    Full Text Available PRholog is an experimental extension of logic programming with strategic conditional transformation rules, combining Prolog with Rholog calculus. The rules perform nondeterministic transformations on hedges. Queries may have several results that can be explored on backtracking. Strategies provide a control on rule applications in a declarative way. With strategy combinators, the user can construct more complex strategies from simpler ones. Matching with four different kinds of variables provides a flexible mechanism of selecting (subterms during execution. We give an overview on programming with strategies in PRholog and demonstrate how rewriting strategies can be expressed.

  13. Strategy as Texts

    DEFF Research Database (Denmark)

    Obed Madsen, Søren

    of the strategy into four categories. Second, the managers produce new texts based on the original strategy document by using four different ways of translation models. The study’s findings contribute to three areas. Firstly, it shows that translation is more than a sociological process. It is also...... a craftsmanship that requires knowledge and skills, which unfortunately seems to be overlooked in both the literature and in practice. Secondly, it shows that even though a strategy text is in singular, the translation makes strategy plural. Thirdly, the article proposes a way to open up the black box of what......This article shows empirically how managers translate a strategy plan at an individual level. By analysing how managers in three organizations translate strategies, it identifies that the translation happens in two steps: First, the managers decipher the strategy by coding the different parts...

  14. Pembajakan Produk: Problema, Strategi dan Antisipasi Strategi

    Directory of Open Access Journals (Sweden)

    Anas Hidayat

    2009-08-01

    Full Text Available Pemakaian ‘merek’ dalam dunia perdagangan telah dilakukan sejak jaman Yunani kuno. Demikian pula peniruan atau pembajakan terhadap produk bermerek. Di abad pertengahan, ancaman sangsi terhadap pe¬langgaran penggunaan merek juga telah dilakukan, misalnya ancaman hukuman gantung bagi para pelaku pem¬bajakan.Di era bisnis modern, bisnis produk bajakan menjadi semakin merajalela dengan skala internasional. Kerjasama internasional antar Negara telah dilakukan dalam menggalang pemberantasan dengan menghasilkan produk-produk hukum penangkalnya. Demikian pula upaya pemerintah domestik masing-masing negara di dunia di bawah koordinasi WTO, telah dan sebagian masih dalam proses menerapkan hukum perlindungan HKI. Misal¬nya Indonesia mencanangkan pemberlakuan UU HKI sejak tahun 2000.Meskipun penelitian di bidang pembajakan produk sudah mulai mendapatkan apresiasi dari para ahli, namun penelitian yang dikaitkan dengan ilmu pemasaran masih tergolong baru, dan hasilnya masih bersifat spo¬radis, belum menemukan konsep teori yang kuat, baik penelitian pada sisi permintaan maupun sisi penawaran produk. Penelitian sisi penawaran memang lebih dahulu mendapatkan perhatian dari para ahli dengan meng¬indentifikasikan strategi masuk pasar para pembajak dan memformulasikan anti strategi pembajakan produk. Namun anti strategi pembajakan produk belum menunjukkan hasil yang efektif, jika dilihat dari kenyataan di lapa¬ngan bahwa pembajakan masih merajalela, terutama di pasar Asia (Callan 1998.Kata Kunci: Pembajakan produk, strategi pembajakan, strategi anti pembajakan

  15. Discursive strategies of strategy in public organizations

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang; Holmgren, Jens; Friis, Ole Uhrskov

    In the last decades, private sector principles and policies have spread into public management. This has fuelled the growth of strategic practices in public service organizations. Although public service organizations typically do not exist in markets or have directs competitors, they tend...... conceptual structures in discourses of strategy in public management. Based on a focus group interview with six management consultants working in a municipality in Denmark, we identify two dimensions regarding how strategy making in public service organizations is given discursive legitimacy. One dimension...

  16. Intermittent search strategies

    Science.gov (United States)

    Bénichou, O.; Loverdo, C.; Moreau, M.; Voituriez, R.

    2011-01-01

    This review examines intermittent target search strategies, which combine phases of slow motion, allowing the searcher to detect the target, and phases of fast motion during which targets cannot be detected. It is first shown that intermittent search strategies are actually widely observed at various scales. At the macroscopic scale, this is, for example, the case of animals looking for food; at the microscopic scale, intermittent transport patterns are involved in a reaction pathway of DNA-binding proteins as well as in intracellular transport. Second, generic stochastic models are introduced, which show that intermittent strategies are efficient strategies that enable the minimization of search time. This suggests that the intrinsic efficiency of intermittent search strategies could justify their frequent observation in nature. Last, beyond these modeling aspects, it is proposed that intermittent strategies could also be used in a broader context to design and accelerate search processes.

  17. POSITIONING STRATEGIES DEVELOPMENT

    OpenAIRE

    Shakhshir Ghassan

    2014-01-01

    The positioning strategy has suffered serious changes in the last few decades, being influenced by the rapid development of competition and the growing focus on specific traits belonging to the market, to the consumer or to the product. The purpose of this paper is to present the developments of theoretical positioning strategies and the orientation from more simple, product oriented strategies, to ones more oriented towards the client and with a briefer period of time. The world is moving in...

  18. Interactive Strategy-Making

    DEFF Research Database (Denmark)

    Andersen, Torben Juul

    2015-01-01

    This article outlines an interactive strategy-making model that combines central reasoning with ongoing learning from decentralised responses. The management literature often presents strategy as implementing an optimal plan identified through rational analysis and ascribes potential shortcomings...... to failed communication and execution of the planned actions. However, effective strategy-making comprises both central reasoning from forward-looking planning considerations and decentralised responses to emerging events as interacting elements in a dynamic adaptive system. The interaction between...

  19. Tvorba strategie PR

    OpenAIRE

    Novosadová, Petra

    2009-01-01

    This diploma thesis deals with the question of Public Relations strategy planning for a company operating in the field of providing travel services. The objective of this thesis is to create such a strategy based on primary and secondary data we have gathered. When doing so we consider the key areas first on theoretical grounds, and then apply them into practice. The outcome of this work is a tailored propsal of Public Relations strategy for a particular business.

  20. PRICE AND PRICING STRATEGIES

    OpenAIRE

    SUCIU Titus

    2013-01-01

    In individual companies, price is one significant factor in achieving marketing success. In many purchase situations, price can be of great importance to customers. Marketers must establish pricing strategies that are compatible with the rest of the marketing mix. Management should decide whether to charge the same price to all similar buyers of identical quantities of a product (a one-price strategy) or to set different prices (a flexible price strategy). Many organizations, especially retai...

  1. Patterns of strategy development

    OpenAIRE

    Bailey, Andy; Johnson, Gerry

    1996-01-01

    This paper builds on a multidimensional framework of strategy development to more clearly understand the processes by which strategy develops within organisations. It reports on a survey based research project which employs senior executives’ perceptions of the strategy development process in their organisations to examine how context specific configurations of dimensions explaining such processes can advance our understanding of strategic management. Six configurations are ide...

  2. Management strategies for business

    OpenAIRE

    Alexander Sumets

    2018-01-01

    The paper aims to systematize business management strategies and identify their potential opportunities for the development of the competitive business advantages in transition economies. Characteristics of the features of modern business in developing countries (on the example of Ukraine) are given in the article in concise form. The relevance of the study of the relationship between strategy and business management is substantiated. Modern interpretations of the concepts of «strategy», «str...

  3. from strategy formulation to strategy formation

    African Journals Online (AJOL)

    Gerhard Louw;Abel Esterhuyse

    ultimately its weakness in accounting for the external environment in realised ..... implements and then controls a strategy that it deems appropriate to achieve an .... Every social system (such as the SANDF) seems to employ information ..... to favour rational analysis over this type of internal debate – in effect, it would.

  4. Secretary Marshall's Employment Strategies

    Science.gov (United States)

    Stevenson, Gloria

    1977-01-01

    A review of proposed employment strategies and priorities of Ray Marshall, Secretary of Labor, with regard to training programs, governmental subsidy programs, apprenticeships, private sector jobs, etc. (WL)

  5. Strategy and New Media

    DEFF Research Database (Denmark)

    Plesner, Ursula; Gulbrandsen, Ib Tunby

    2015-01-01

    Despite current attention to the materiality of organizations and the performative role of tools, devices, artefacts and objects in processes of strategy-making, the impact of new media has not been thoroughly conceptualized in the strategy literature. We argue that new media challenge core...... assumptions in strategy about control, boundaries and choice. To understand their constitutive effects and the implications for strategy-making, it is necessary to develop a research agenda oriented towards understanding technological affordances – but not only in local practices. Due to vital characteristics...

  6. Processuel strategi i organisationer

    DEFF Research Database (Denmark)

    Gylling, Martin

    2014-01-01

    on process theory and strategy, which in these years aims to move focus away from the dominance of designed strategy. I.e. an approach to practice understood as methodological individualism and pragmatic rationality (Chia & Holt 2009; Steyaert 2007; Stacey 2011; Hjorth 2012). Through recent poststructuralist...... currents in the field of processual strategy thinking and organisational entrepreneurship, for example Chia & Holt’s creation philosophical research in strategy without design and Steyaert’s (2007) thinking on the concept of entrepreneuring; the process theoretical thinking of entrepreneurship...

  7. The advertising strategies

    Institute of Scientific and Technical Information of China (English)

    YAKOUBI Mohamed Lamine

    2013-01-01

    We will try to demonstrate, through the display of the various advertising creation strategies and their evolution, how the advertising communication passed from of a vision or a strategy focused on the product, to a vision focused on the brand. The first advertising strategy that was applied by advertising agencies is the"Unique Selling Proposition";it focused only on the product advantages and its philosophy dominated the advertising world, throughout its various evolutions, till the nineties but this is without counting the introduction of the new advertising strategies that brought a more brand oriented philosophy to the ground.

  8. Entrepreneurial Barriers to Strategy

    DEFF Research Database (Denmark)

    Elkjær, Jørgen Ravn

    2013-01-01

    En begrænsende faktor for strategisk ledelse er ofte iværksætterens uddannelse og erfaring, som efter en del forskningsbidrag synes at både fremme og hæmme bestemte strategie. Desuden kan der i hierarkier være en tendens til at opretholde de strategier, som blev dannet ved stiftelsen. Organisator...

  9. Geometric leaf placement strategies

    International Nuclear Information System (INIS)

    Fenwick, J D; Temple, S W P; Clements, R W; Lawrence, G P; Mayles, H M O; Mayles, W P M

    2004-01-01

    Geometric leaf placement strategies for multileaf collimators (MLCs) typically involve the expansion of the beam's-eye-view contour of a target by a uniform MLC margin, followed by movement of the leaves until some point on each leaf end touches the expanded contour. Film-based dose-distribution measurements have been made to determine appropriate MLC margins-characterized through an index d 90 -for multileaves set using one particular strategy to straight lines lying at various angles to the direction of leaf travel. Simple trigonometric relationships exist between different geometric leaf placement strategies and are used to generalize the results of the film work into d 90 values for several different strategies. Measured d 90 values vary both with angle and leaf placement strategy. A model has been derived that explains and describes quite well the observed variations of d 90 with angle. The d 90 angular variations of the strategies studied differ substantially, and geometric and dosimetric reasoning suggests that the best strategy is the one with the least angular variation. Using this criterion, the best straightforwardly implementable strategy studied is a 'touch circle' approach for which semicircles are imagined to be inscribed within leaf ends, the leaves being moved until the semicircles just touch the expanded target outline

  10. Green product innovation strategy

    NARCIS (Netherlands)

    Driessen, P.H.

    2005-01-01

    Over the last decades, companies have started to incorporate green issues in product innovation strategies. This dissertation studies green product innovation strategy, its antecedents and its outcomes. A three-stage approach is followed. In the first stage, the topic is explored and a preliminary

  11. Value oriented marketing strategies

    Directory of Open Access Journals (Sweden)

    Stanković Ljiljana

    2009-01-01

    Full Text Available The complexity of business environment imposes the need for continuous change and reexamination of business marketing strategies of enterprises. Theory and practice of strategic management and marketing show that the activities of marketing, which are closely connected to corporate strategy, are the key drivers of growth. There is a positive correlation between competition intensity, marketing strategy and business performance of companies. Even though, managers of many companies don't see a clear connection between marketing strategy and business performance, numerous empirical research show that the companies which possess and efficiently use marketing resources and capabilities are more successful. In knowledge-based economics, the development of value oriented marketing strategies for all participants in the chain is a supposition of the survival, growth and development of companies. Competitive advantage is the essence of any strategy. Acquisition and maintenance of competitive advantage is more successful if the potentials for value creation are used efficiently. The paper examines the critical factors that influence alignment and transformation of marketing strategies in accordance with changes in value estimation. Superior value, is created in different network classes. Theory and practice researches create a reliable basis for the development of new concepts, marketing strategy business models that will contribute to competitive advantage of enterprises and the economy.

  12. Multimodal Strategies of Theorization

    DEFF Research Database (Denmark)

    Cartel, Melodie; Colombero, Sylvain; Boxenbaum, Eva

    This paper examines the role of multimodal strategies in processes of theorization. Empirically, we investigate the theorization process of a highly disruptive innovation in the history of architecture: reinforced concrete. Relying on archival data from a dominant French architectural journal from...... with well-known rhetorical strategies and develop a process model of theorization....

  13. Listening strategies instruction

    DEFF Research Database (Denmark)

    Nogueroles López, Marta

    2017-01-01

    , who presented similar level of Spanish, needs, educational and cultural background, but did not receive such a training. The listening strategies instruction consisted in integrating the development of listening strategies into a regular course of Spanish as a foreign language. Data referring...

  14. Introduction: Experimental Green Strategies

    DEFF Research Database (Denmark)

    Peters, Terri

    2011-01-01

    Defining new ways in which archietcts are responding to the challenge of creating sustainable architecture , Experimental Green Strategies present a state of the art in applied ecological architectural research.......Defining new ways in which archietcts are responding to the challenge of creating sustainable architecture , Experimental Green Strategies present a state of the art in applied ecological architectural research....

  15. Strategies for Competitive Volleyball.

    Science.gov (United States)

    Fraser, Stephen D.

    This book deals with strategies and team tactics involved in the game of volleyball. It is not intended to be an instructional book on how to execute the various skills required to play volleyball but instead endeavors to detail and explain basic tactics and strategies involved in volleyball team play. Each chapter deals with major areas of team…

  16. Strategy as a Virus

    DEFF Research Database (Denmark)

    Obed Madsen, Søren

    This article is based on virus theory (Røvik, 2007, 2011), and proposes to develop a framework that defines technology as a virus that penetrates the organism of an organization. The framework develops a new vocabulary, which can help in analyzing technologies and their negative effects on actors...... and organizations. In this paper, the virus theory is used to analyze a strategy process in an organization as an example of a technology. It shows how the strategy over time creates a memory loss, where the managers who are exposed to the virus forget their critique of the new strategy concept. The article also...... shows how resistant can be understood as being immune to a virus, since the strategy concepts bears resemblance to a former strategy concept. The article also argues that there should be more focus on the negative impacts of management tool and especially how organizations and managers are dealing...

  17. Strategies of inducing cooperation

    International Nuclear Information System (INIS)

    Deutsch, M.

    1986-01-01

    The results of the four experiments described in this paper are very consistent, and they can be summarized as follows: (1) The ''nonpunitive'' strategy was most effective in eliciting cooperative behavior from the subjects and, overall, resulted in the highest joint outcomes as well as the highest outcomes for the accomplice. (2) The effectiveness of the turn-the-other-cheek strategy was very much influenced by the competitiveness of the situation; the more competitive the incentives of the subjects, the more massively they exploited the accomplice who employed this strategy. (3) The punitive deterrent strategy elicited more agressive and self-protective, as well as less cooperative, behavior from the subjects than did the other strategies

  18. Strategy as simple rules.

    Science.gov (United States)

    Eisenhardt, K M; Sull, D N

    2001-01-01

    The success of Yahoo!, eBay, Enron, and other companies that have become adept at morphing to meet the demands of changing markets can't be explained using traditional thinking about competitive strategy. These companies have succeeded by pursuing constantly evolving strategies in market spaces that were considered unattractive according to traditional measures. In this article--the third in an HBR series by Kathleen Eisenhardt and Donald Sull on strategy in the new economy--the authors ask, what are the sources of competitive advantage in high-velocity markets? The secret, they say, is strategy as simple rules. The companies know that the greatest opportunities for competitive advantage lie in market confusion, but they recognize the need for a few crucial strategic processes and a few simple rules. In traditional strategy, advantage comes from exploiting resources or stable market positions. In strategy as simple rules, advantage comes from successfully seizing fleeting opportunities. Key strategic processes, such as product innovation, partnering, or spinout creation, place the company where the flow of opportunities is greatest. Simple rules then provide the guidelines within which managers can pursue such opportunities. Simple rules, which grow out of experience, fall into five broad categories: how- to rules, boundary conditions, priority rules, timing rules, and exit rules. Companies with simple-rules strategies must follow the rules religiously and avoid the temptation to change them too frequently. A consistent strategy helps managers sort through opportunities and gain short-term advantage by exploiting the attractive ones. In stable markets, managers rely on complicated strategies built on detailed predictions of the future. But when business is complicated, strategy should be simple.

  19. Bepaling van aminozuren met hoge druk vloeistofchromatografie. II Derivatisering met dabsylchloride

    NARCIS (Netherlands)

    Both-Miedema R; Jansen EHJM

    1990-01-01

    Several pre-column derivatization methods have been reported for the determination of amino acids using high performance liquid chromatography (HPLC). the present report describes the derivatization procedure of amino acids with dabsylchloride and the HPLC analysis of dabsyl-amino acids for a

  20. High performance liquid chromatographic determination of Ginseng saponin by ultraviolet derivatisation

    International Nuclear Information System (INIS)

    Besso, H.; Saruwatari, Y.; Futamura, K.; Kunihiro, K.; Fuwa, T.; Tanaka, O.

    1979-01-01

    Ginsenoides Rb 1 , b 2 , c, d, e and g 1 quantitatively reacted with benzoyl chloride in pyridine to afford the respective derivatives having strong UV absorption. The UV-derivatized saponins were separated by high performance liquid chromatography (HPLC), and the saponin-contents of the various Ginseng varieties were determined. It is possible to distinguish white Ginseng from the root hairs of Ginseng by the pattern analysis of HPLC. (orig.) [de

  1. A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic

    Directory of Open Access Journals (Sweden)

    Marcus Baumann

    2017-11-01

    Full Text Available An assembled suite of flow-based transformations have been used to rapidly scale-up the production of a novel auxin mimic-based herbicide which was required for preliminary field trials. The overall synthetic approach and optimisation studies are described along with a full description of the final reactor configurations employed for the synthesis as well as the downstream processing of the reaction streams.

  2. Self-assembled monolayers of a disulphide-derivatised cobalt-porphyrin on gold

    International Nuclear Information System (INIS)

    Viana, A.S.; Leupold, S.; Montforts, F.-P.; Abrantes, L.M.

    2005-01-01

    A self-assembled monolayer (SAM) of a novel cobalt(II)porphyrin disulphide derivative was prepared on flat gold(1 1 1) electrode. Evidence for surface modification was provided by electrochemical reductive desorption of the monolayer and ellipsometry, consistent with a coverage of 2.5 x 10 -10 mol cm -2 and a thickness of 13 A, respectively. Both results support the presence of SAMs where the molecules share an intermediate position between perpendicular and flat orientation. Scanning tunnelling microscopy have also proven the formation of CoPSS SAMs, however high-resolution images could only be obtained when the CoPSS molecules were diluted in an hexanethiol SAM. The electrocatalytic activity of the surface confined Co-porphyrin was evaluated for the oxygen reduction. Voltammetric data indicate that reaction involves two electrons consistent with the formation of hydrogen peroxide. Under similar experimental conditions the data obtained for an iron-porphyrin analogue points for a full reduction of dioxygen to water

  3. Guinea pig Ia antigens are not derivatised on trinitrophenyl-modified cells

    Energy Technology Data Exchange (ETDEWEB)

    Clement, L T; Thomas, D W; Kask, A M; Shevach, E M [National Inst. of Allergy and Infectious Diseases, Bethesda, MD (USA)

    1978-08-10

    In an effort to clarify the nature of the trinitrophenyl (TNP) specific immunogen recognised by hapten-reactive guinea pig T lymphocytes, the membrane proteins of TNP-modified guinea pig macrophages have been analysed by chemical methods using nitrobenzene sulphonic acid surface labelled with /sup 125/I. The experiments provided strong evidence that the TNP specific immunogen which T lymphocytes recognise on guinea pig macrophages does not consist of directly haptenated Ia antigens.

  4. Pre-column derivatisation method for the measurement of glycosylated hydroxylysines of collagenous proteins

    NARCIS (Netherlands)

    Bank, R.A.; Beekman, B.; Tenni, R.; Tekoppele, J.M.

    1997-01-01

    Measurement of the glycosylated hydroxylysines galactosyl- and glucosylgalactosylhydroxylysine (GH and GGH) in combination with other amino acids has been based on ion-exchange chromatography followed by reaction with ninhydrin. Here, a rapid and sensitive high-performance liquid chromatographic

  5. DOE groundwater protection strategy

    International Nuclear Information System (INIS)

    Lichtman, S.

    1988-01-01

    EH is developing a DOE-wide Groundwater Quality Protection Strategy to express DOE's commitment to the protection of groundwater quality at or near its facilities. This strategy responds to a September 1986 recommendation of the General Accounting Office. It builds on EPA's August 1984 Ground-Water Protection Strategy, which establishes a classification system designed to protect groundwater according to its value and vulnerability. The purposes of DOE's strategy are to highlight groundwater protection as part of current DOE programs and future Departmental planning, to guide DOE managers in developing site-specific groundwater protection practices where DOE has discretion, and to guide DOE's approach to negotiations with EPA/states where regulatory processes apply to groundwater protection at Departmental facilities. The strategy calls for the prevention of groundwater contamination and the cleanup of groundwater commensurate with its usefulness. It would require long-term groundwater protection with reliance on physical rather than institutional control methods. The strategy provides guidance on providing long-term protection of groundwater resources; standards for new remedial actions;guidance on establishing points of compliance; requirements for establishing classification review area; and general guidance on obtaining variances, where applicable, from regulatory requirements. It also outlines management tools to implement this strategy

  6. Typhoid fever vaccination strategies.

    Science.gov (United States)

    Date, Kashmira A; Bentsi-Enchill, Adwoa; Marks, Florian; Fox, Kimberley

    2015-06-19

    Typhoid vaccination is an important component of typhoid fever prevention and control, and is recommended for public health programmatic use in both endemic and outbreak settings. We reviewed experiences with various vaccination strategies using the currently available typhoid vaccines (injectable Vi polysaccharide vaccine [ViPS], oral Ty21a vaccine, and injectable typhoid conjugate vaccine [TCV]). We assessed the rationale, acceptability, effectiveness, impact and implementation lessons of these strategies to inform effective typhoid vaccination strategies for the future. Vaccination strategies were categorized by vaccine disease control strategy (preemptive use for endemic disease or to prevent an outbreak, and reactive use for outbreak control) and vaccine delivery strategy (community-based routine, community-based campaign and school-based). Almost all public health typhoid vaccination programs used ViPS vaccine and have been in countries of Asia, with one example in the Pacific and one experience using the Ty21a vaccine in South America. All vaccination strategies were found to be acceptable, feasible and effective in the settings evaluated; evidence of impact, where available, was strongest in endemic settings and in the short- to medium-term. Vaccination was cost-effective in high-incidence but not low-incidence settings. Experience in disaster and outbreak settings remains limited. TCVs have recently become available and none are WHO-prequalified yet; no program experience with TCVs was found in published literature. Despite the demonstrated success of several typhoid vaccination strategies, typhoid vaccines remain underused. Implementation lessons should be applied to design optimal vaccination strategies using TCVs which have several anticipated advantages, such as potential for use in infant immunization programs and longer duration of protection, over the ViPS and Ty21a vaccines for typhoid prevention and control. Copyright © 2015. Published by

  7. Cooperative strategies European perspectives

    CERN Document Server

    Killing, J Peter

    1997-01-01

    Cooperative Strategies: European Perspectives is one of three geographically targeted volumes in which the contributors present the most current research on topics such as advances in theories of cooperative strategies, the formation of cooperative alliances, the dynamics of partner relationships, and the role of information and knowledge in cooperative alliances. Blending conceptual insights with empirical analyses, the contributors highlight commonalities and differences across national, cultural, and trade zones. The chapters in this volume are anchored in a wide set of theoretical approaches, conceptual frameworks, and models, illustrating how rich the area of cooperative strategies is for scholarly inquiry.

  8. Strategy as Performative Practice

    DEFF Research Database (Denmark)

    Kornberger, Martin; Clegg, Stewart

    2011-01-01

    is it based upon? And what are its power effects? Based on a detailed empirical analysis of the strategy-making process, the article charts how strategy rendered the city knowable and how performative effects of strategizing mobilized the public and legitimized outcomes of the process while silencing other...... (traditionally the domain of science) and values (the realm of politics); third, and consequently, that strategy is a sociopolitical practice that aims at mobilizing people, marshalling political will and legitimizing decisions. The article concludes with reflections on five practical implications of the study....

  9. Genesis nature of financial strategy

    OpenAIRE

    O.V. Pashchenko

    2015-01-01

    The article is devoted to the study of the origin and history of the interpretation of the genesis of «strategy», «financial strategy», its elements and composite types. Scientists studied different views on the concept of strategy. Several specific positions founders of different approaches to define the strategy of schools operating strategies involved in the formulation and implementation of the concept of «strategy». Evaluation of different schools of strategies that deepened understandin...

  10. Price strategy and pricing strategy: terms and content identification

    OpenAIRE

    Panasenko Tetyana

    2015-01-01

    The article is devoted to the terminology and content identification of seemingly identical concepts "price strategy" and "pricing strategy". The article contains evidence that the price strategy determines the direction, principles and procedure of implementing the company price policy and pricing strategy creates a set of rules and practical methods of price formation in accordance with the pricing strategy of the company.

  11. The relationship between Business Strategy, IT Strategy and Alignment Capability

    NARCIS (Netherlands)

    Drs. A.J.G. Silvius

    2009-01-01

    Aligning business and IT strategy is a prominent area of concern. Organizations that successfully align their business strategy and their IT strategy, outperform their non-aligned peers (Chan et al., 1997). This chapter explores the relationship between business strategy, IT strategy and alignment

  12. A New Distribution Strategy : The Omnichannel Strategy

    Directory of Open Access Journals (Sweden)

    Mihaela Gabriela Belu

    2014-06-01

    Full Text Available In an increasingly globalized world, dependent on information technology, distribution companies are searching for new marketing models meant to enrich the consumer’s experience. Therefore, the evolution of new technologies, the changes in the consumer’s behaviour are the main factors that determine changes in the business model in the distribution field. The following article presents different forms of distribution, focusing on the omnichannel strategy. In the last part of the paper, the authors analyse the Romanian retail market, namely, the evolution of the market, its key competitors and the new distribution models adopted by retaileres in our country.

  13. Information transmission strategy

    International Nuclear Information System (INIS)

    Moreau, A.

    1989-01-01

    The four propositions on which our radiation protection information transmission strategy is based are as follows: 1. Emotion exists. It rules our lives at work as well as at home, particularly when radiation safety is involved. Emotion is therefore the terrain for our strategy. 2. The basic emotion is that of fear. This must be recognized and accepted if we want to transmit objective information. The basis of our strategy is therefore listening. 3. A person cannot be divided into parts. The whole person is concerned about safety. We have to deal with that whole person. 4. To follow a strategy we need strategists. We must look at our own emotions and our own motivation before going into the field

  14. Qualitative Data Analysis Strategies

    OpenAIRE

    Greaves, Kristoffer

    2014-01-01

    A set of concept maps for qualitative data analysis strategies, inspired by Corbin, JM & Strauss, AL 2008, Basics of qualitative research: Techniques and procedures for developing grounded theory, 3rd edn, Sage Publications, Inc, Thousand Oaks, California.

  15. Strategy as Projects

    DEFF Research Database (Denmark)

    Lund Pedersen, Carsten; Ritter, Thomas; Andersen, Torben Juul

    This paper proposes the adoption of a project-based view to analyze strategy formation and strategic renewal over time. Projects are resource-committing, empirically-tracable investments, and as such, particularly suitable for the analysis of different manifestations of intended strategies as well...... as post-hoc manifestations of deviant, even rebellious, actions taken in opposition to the initial strategy announcement. The paper presents an analytical framework (a 5x2 matrix) of ten different project categories that together allows researchers to investigate how strategic renewal is realized through...... the enactment of different types of project initiatives throughout the organization. The developed framework is validated by two field studies that outline the robustness of the proposed matrix. In addition to the demonstration of the advantages of the framework, we discuss the limitations of the strategy-as-projects...

  16. Compositional Advantage and Strategy

    DEFF Research Database (Denmark)

    Li, Xin

    advantage is redefined as the attractiveness of the composition of the producer’s offering in terms of scope and perceived value/price ratio. I identify five ways or basic compositional strategies to improve the value/price ratio. A firm may have an overall compositional strategy that is composed of some......In this paper, I first critique the composition-based view of Yadong Luo and John Child for understanding how resource-poor firms survive and thrive. To remedy the deficiencies in their perspective, I then propose a dynamic theory of compositional advantage and strategy. Here, the compositional...... or all of the five basic compositional strategies. I argue there are three indispensable key success factors for a composition-based competition, i.e., aspiration (ambition-position asymmetry), attitude (being ALERT), and action (turning asymmetry into advantage). I also discuss the particular relevance...

  17. Combustion strategy : United Kingdom

    Energy Technology Data Exchange (ETDEWEB)

    Greenhalgh, D. [Heriot-Watt Univ., Edingburgh, Scotland (United Kingdom). School of Engineering and Physical Sciences

    2009-07-01

    The United Kingdom's combustion strategy was briefly presented. Government funding sources for universities were listed. The United Kingdom Research Councils that were listed included the Arts and Humanities Research Council (AHRC) and the Biotechnology and Biological Sciences Research Council (BBSRC); the Engineering and Physical Sciences Research Council (EPSRC); the Economic and Social Research Council; the Medical Research Council; the Natural Environment Research Council; and the Science and Technology Facilities Council. The EPSRC supported 65 grants worth 30.5 million pounds. The combustion industry was noted to be dominated by three main players of which one was by far the largest. The 3 key players were Rolls-Royce; Jaguar Land Rover; and Doosan Babcock. Industry and government involvement was also discussed for the BIS Technology Strategy Board, strategy technology areas, and strategy application areas.

  18. INTEGRATED CORPORATE STRATEGY MODEL

    Directory of Open Access Journals (Sweden)

    CATALINA SORIANA SITNIKOV

    2014-02-01

    Full Text Available Corporations are at present operating in demanding and highly unsure periods, facing a mixture of increased macroeconomic need, competitive and capital market dangers, and in many cases, the prospect for significant technical and regulative gap. Throughout these demanding and highly unsure times, the corporations must pay particular attention to corporate strategy. In present times, corporate strategy must be perceived and used as a function of various fields, covers, and characters as well as a highly interactive system. For the corporation's strategy to become a competitive advantage is necessary to understand and also to integrate it in a holistic model to ensure sustainable progress of corporation activities under the optimum conditions of profitability. The model proposed in this paper is aimed at integrating the two strategic models, Hoshin Kanri and Integrated Strategy Model, as well as their consolidation with the principles of sound corporate governance set out by the OECD.

  19. Defeating Saddam Hussein's Strategy

    National Research Council Canada - National Science Library

    Millen, Raymond A

    2003-01-01

    Should war break out between Iraq and the United States, Saddam Hussein will likely adopt a strategy designed to undermine the prestige of the United States and turn the Arab World against the West...

  20. US Strategy for Cyberspace

    National Research Council Canada - National Science Library

    Veazie, Arnold

    2003-01-01

    .... in conventional warfare. As a result, America's adversaries are adopting asymmetrical warfare approaches, such as cyber attacks, as part of their strategy to disrupt the American infrastructure and economy...

  1. SPORT PROMOTION STRATEGIES

    Directory of Open Access Journals (Sweden)

    Alexandru Lucian MIHAI

    2013-10-01

    Full Text Available In sport marketing, the word promotion covers a range of interrelated activities. All of these activities are designed to attract attention, stimulate the interest and awareness of consumers, and of course, encourage them to purchase a sport product. Promotion is about communicating with and educating consumers. The purpose of a sport promotional strategy is to build brand loyalty and product credibility, develop image, and position the brand. A promotional strategy is similar to a marketing strategy, but the promotional strategy seeks short-term objectives, both direct and indirect. Promotional objectives usually include increased sales, stimulate impulse buying, raise customer traffic, and present and reinforce image. It also provides information about products and services, publicizes new stores or websites, and creates and enhances customer satisfaction.

  2. Consolidating Social Media Strategies

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia; Munar, Ana Maria; Larson, Mia

    2014-01-01

    This study revisits and integrates the insights of recent studies on emergent social media strategies deployed by destination and event management organisations. In a comparative analysis Munar (2012) identified four generic approaches pursued by national tourism boards in the Nordic region, while...... Gyimóthy & Larson (2014) portrayed three digital value co-creation strategies deployed by festival social media. Both frameworks provided novel analytical typologies which identified a series of categories (mimetic, analytic, immersion, advertising and insourcing, crowdsourcing and community consolidation......). This paper discusses the complementary nature of these conceptual proposals and advances an integrated conceptual framework of social media strategies. Based on the empirical findings of a case study that revisits evolving digital and social media strategies of European DMOs this paper maps the dynamics...

  3. Enacting Governance through Strategy

    DEFF Research Database (Denmark)

    Brandtner, Christof; Höllerer, Markus A.; Meyer, Renate E.

    2017-01-01

    of strategy documents in city administration addresses these challenges. Our central claim is that strategy documents can be understood as a distinct discursive device through which local governments enact aspired governance configurations. We illustrate our argument empirically using two prominent examples...... that, while showing similar features and characteristics, are anchored in different administrative traditions and institutional frameworks: the city administrations of Sydney, Australia, and Vienna, Austria. The contribution of the paper is to show how strategy documents enact governance configurations...... along four core dimensions: the setting in space and time, the definition of the public, the framing of the res publica and legitimacy issues. Moreover, our comparative analysis of Sydney and Vienna gives evidence of differences in governance configurations enacted through strategy documents....

  4. E-commerce strategy

    CERN Document Server

    Qin, Zheng; Li, Shundong; Li, Fengxiang

    2014-01-01

    This book helps deepen understanding of key e-commerce strategies. It brings together theoretical perspectives based on academic research, integrated use of technologies and a large amount of cases, especially those of China.

  5. Forces in strategy formation

    DEFF Research Database (Denmark)

    Steensen, Elmer Fly; Sanchez, Ron

    2008-01-01

    This chapter proposes that organizational strategy formation should be characterized theoretically as a process that is subject to several interacting forces, rather than represented by separate discrete decisionmodels or theoretic perspectives, as is commonly done in the strategic management...... literature. Based on an extensive review of relevant theory and empirical work in strategic decision-making, organizational change theory, cognitive and social psychology, and strategy processes, seven kinds of ''forces'' - rational, imposed, teleological, learning, political, heuristic, and social...... - are identified as interacting in and having significant influence on the strategy formation process. It is further argued that by applying a holistic ''forces-view'' of the significant and interacting influences on strategy formation, we can better understand the dynamics and challenges in managing the process...

  6. Resources, Technology, and Strategy

    DEFF Research Database (Denmark)

    Resources, Technology and Strategy brings together contributors from Europe, North America and Asia to consider the strategic relationship between technology and other resources, such as production capabilities, marketing prowess, finance and organisational culture. Throughout the book...

  7. Organizing export strategies.

    OpenAIRE

    G. Lojacono; M. Venzin

    2014-01-01

    The article unfolds as follows: after a brief introduction on the relevance of international trade and the characteristics of export strategies, we describe four distinct archetypes: export manager, centralistic export developer, export skimmer, integrated export developer.

  8. Cloud computing strategies

    CERN Document Server

    Chorafas, Dimitris N

    2011-01-01

    A guide to managing cloud projects, Cloud Computing Strategies provides the understanding required to evaluate the technology and determine how it can be best applied to improve business and enhance your overall corporate strategy. Based on extensive research, it examines the opportunities and challenges that loom in the cloud. It explains exactly what cloud computing is, what it has to offer, and calls attention to the important issues management needs to consider before passing the point of no return regarding financial commitments.

  9. Strategi Pembelajaran Tanpa Kekerasan

    OpenAIRE

    Idrus, Muhammad

    2013-01-01

    This paper will discuss learning strategy models which put student as subject of learning. Teacher is expected to take an advantage in using those models to reduce violence in education circumstance. As found in researches and mass media, violence in education circumstances, which is performed by teachers or students, still become high concerns among parents, teachers, and students themselves. One such thing that may cause this violence is learning and teaching approach or strategy by which t...

  10. Hexavalent Chromium Minimization Strategy

    Science.gov (United States)

    2011-05-01

    Logistics 4 Initiative - DoD Hexavalent Chromium Minimization Non- Chrome Primer IIEXAVAJ ENT CHRO:M I~UMI CHROMIUM (VII Oil CrfVli.J CANCEfl HAnRD CD...Management Office of the Secretary of Defense Hexavalent Chromium Minimization Strategy Report Documentation Page Form ApprovedOMB No. 0704-0188...00-2011 4. TITLE AND SUBTITLE Hexavalent Chromium Minimization Strategy 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

  11. Management strategies for fibromyalgia

    OpenAIRE

    Le Marshall KF; Littlejohn GO

    2011-01-01

    Kim Francis Le Marshall, Geoffrey Owen LittlejohnDepartments of Rheumatology and Medicine, Monash Medical Centre and Monash University, Victoria, AustraliaDate of preparation: 14 June 2011Clinical question: What are the effective, evidence-based strategies available for the management of fibromyalgia?Conclusion: There are a number of management strategies available with robust evidence to support their use in clinical practice.Definition: Fibromyalgia is a complex pain syndrome characterized ...

  12. Strategies in digital marketing

    OpenAIRE

    Robert DRAGOMIR; Mihai ANDRONIE

    2017-01-01

    The present paper deals with digital marketing. The approach into discussion is the strategies met with the concept mentioned above. Within the actual socio-economic context, the electronic equipments offer on one hand new and innovative methods for products promoting and, on the other hand new challenges for the consumers. Thus, we analysed different and major types of strategies, which have a great impact on the digital marketing.

  13. Marketing Strategy for Kukaneko

    OpenAIRE

    Kämpjärvi, Tiina

    2013-01-01

    The topic of this thesis was to create a realistic marketing strategy for Kukaneko that sells Finnish sustainable fashion in Lahti. The company had no comprehensive marketing strategy in its use which why this thesis was written. Both secondary and primary research was used to carry out the research. The secondary data was gathered from books, scholarly journals and internet sources. Qualitative data was gathered in co-operation with the owner of the case company through an interview...

  14. Social Media Cocreation Strategies

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia; Larson, Mia

    2015-01-01

    This paper explores how social media becomes a part of integrated marketing communications of festival organizations. The purpose of this paper is to conceptualize the co-creation of festival experiences online by comparing managerial strategies and communicative patterns of three large....... Based on the empirical findings, we propose an analytical framework to improve our understanding of the management of social media communications, offering three distinct value co-creation strategies in a festival context....

  15. Human Life History Strategies.

    Science.gov (United States)

    Chua, Kristine J; Lukaszewski, Aaron W; Grant, DeMond M; Sng, Oliver

    2017-01-01

    Human life history (LH) strategies are theoretically regulated by developmental exposure to environmental cues that ancestrally predicted LH-relevant world states (e.g., risk of morbidity-mortality). Recent modeling work has raised the question of whether the association of childhood family factors with adult LH variation arises via (i) direct sampling of external environmental cues during development and/or (ii) calibration of LH strategies to internal somatic condition (i.e., health), which itself reflects exposure to variably favorable environments. The present research tested between these possibilities through three online surveys involving a total of over 26,000 participants. Participants completed questionnaires assessing components of self-reported environmental harshness (i.e., socioeconomic status, family neglect, and neighborhood crime), health status, and various LH-related psychological and behavioral phenotypes (e.g., mating strategies, paranoia, and anxiety), modeled as a unidimensional latent variable. Structural equation models suggested that exposure to harsh ecologies had direct effects on latent LH strategy as well as indirect effects on latent LH strategy mediated via health status. These findings suggest that human LH strategies may be calibrated to both external and internal cues and that such calibrational effects manifest in a wide range of psychological and behavioral phenotypes.

  16. Human Life History Strategies

    Directory of Open Access Journals (Sweden)

    Kristine J. Chua

    2016-12-01

    Full Text Available Human life history (LH strategies are theoretically regulated by developmental exposure to environmental cues that ancestrally predicted LH-relevant world states (e.g., risk of morbidity–mortality. Recent modeling work has raised the question of whether the association of childhood family factors with adult LH variation arises via (i direct sampling of external environmental cues during development and/or (ii calibration of LH strategies to internal somatic condition (i.e., health, which itself reflects exposure to variably favorable environments. The present research tested between these possibilities through three online surveys involving a total of over 26,000 participants. Participants completed questionnaires assessing components of self-reported environmental harshness (i.e., socioeconomic status, family neglect, and neighborhood crime, health status, and various LH-related psychological and behavioral phenotypes (e.g., mating strategies, paranoia, and anxiety, modeled as a unidimensional latent variable. Structural equation models suggested that exposure to harsh ecologies had direct effects on latent LH strategy as well as indirect effects on latent LH strategy mediated via health status. These findings suggest that human LH strategies may be calibrated to both external and internal cues and that such calibrational effects manifest in a wide range of psychological and behavioral phenotypes.

  17. Social strategies that work.

    Science.gov (United States)

    Piskorski, Mikołaj Jan

    2011-11-01

    Although most companies have collected lots of friends and followers on social platforms such as Facebook, few have succeeded in generating profits there. That's because they merely port their digital strategies into social environments by broadcasting their commercial messages or seeking customer feedback. To succeed on social platforms, says Harvard Business School's Piskorski, businesses need to devise social strategies that are consistent with users' expectations and behavior in these venues--namely, people want to connect with other people, not with companies. The author defines successful social strategies as those that reduce costs or increase customers' willingness to pay by helping people establish or strengthen relationships through doing free work on a company's behalf. Citing successes at Zynga, eBay, American Express, and Yelp, Piskorski shows that social strategies can generate profits by helping people connect in exchange for tasks that benefit the company such as customer acquisition, marketing, and content creation. He lays out a systematic way to build a social strategy and shows how a major credit card company he advised used the method to roll out its own strategy.

  18. Lithuanian Energy Strategy

    International Nuclear Information System (INIS)

    Valentukevichius, V.

    1999-01-01

    The First National Energy Strategy, outlining the principal provisions of the Government on the reconstruction and development of energy sector, was approved for a comparatively long period - until the year 2015. The Energy Law envisages that the energy strategy is approved by the Parliament and has to be revised every five year. This National Energy Strategy amended and specified the energy development trends defined in 1994. The recent positive developments and tendencies in Lithuania's economy called for the necessity to revise the strategies for the further development of the infra structural areas, especially the energy sector. The preparation of an updated National Energy Strategy was based on the overall forecasts for the development of the country, and also experience, which was gained by participation in the programmes and studies supported by European Union and PHARE, and also priorities indicated in the National Programme for Adoption of Acquis (NPAA programme). Formulation of the basic goals of the National Energy Strategy included requirements of the European Association Agreement, Energy Charter, and also principles and tendencies in the energy sector development of the member countries

  19. Decommissioning strategy selection

    International Nuclear Information System (INIS)

    Warnecke, E.

    2005-01-01

    At the end of their useful life nuclear facilities have to be decommissioned. The strategy selection on how to decommission a facility is a highly important decision at the very beginning of decommissioning planning. Basically, a facility may be subject to (a) immediate dismantling; (b) deferred dismantling after a period of ''safe enclosure'' or (c) entombment where a facility is turned into a near surface disposal facility. The first two strategies are normally applied. The third one may be accepted in countries without significant nuclear activities and hence without disposal facilities for radioactive waste. A large number of factors has to be taken into account when a decision on the decommissioning strategy is being made. Many of the factors cannot be quantified. They may be qualitative or subject to public opinion which may change with time. At present, a trend can be observed towards immediate dismantling of nuclear facilities, mainly because it is associated with less uncertainty, less local impact, a better public acceptance, and the availability of operational expertise and know how. A detailed evaluation of the various factors relevant to strategy selection and a few examples showing the situation regarding decommissioning strategy in a number of selected countries are presented in the following article. (orig.)

  20. APL: a corporate strategy.

    Science.gov (United States)

    Fox, J; Nyatanga, L; Ringer, C; Greaves, J

    1992-06-01

    This paper is based on, and summarises, papers read at the second annual international conference of Nurse Education Tomorrow held at the University of Durham (UK) September 1991. To this end this paper will offer: Some Accreditation of Prior Learning (APL) definition and process as reflected in the literature available. A distinction will be made between APL and Accreditation of Prior Experiential Learning (APEL) although the procedures and processes for assessing them will be shown to be the same. A brief outline of corporate strategy, as it applies to APL, will be given to form the basis for logical demonstration of how Derbyshire Institute of Health and Community Studies has employed such a corporate strategy. Insights developed and gained from APL research currently being undertaken through the college of nursing and midwifery will be used to inform the development and nature of corporate strategy. A flowchart of the operationalisation of the corporate strategy is offered as an integrative summary of how all the APL ideas have had a positive cumulative effect. The paper finishes by highlighting the possible strengths and limitations of APL corporate strategy.

  1. Comprehensive national energy strategy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    This Comprehensive National Energy Strategy sets forth a set of five common sense goals for national energy policy: (1) improve the efficiency of the energy system, (2) ensure against energy disruptions, (3) promote energy production and use in ways that respect health and environmental values, (4) expand future energy choices, and (5) cooperate internationally on global issues. These goals are further elaborated by a series of objectives and strategies to illustrate how the goals will be achieved. Taken together, the goals, objectives, and strategies form a blueprint for the specific programs, projects, initiatives, investments, and other actions that will be developed and undertaken by the Federal Government, with significant emphasis on the importance of the scientific and technological advancements that will allow implementation of this Comprehensive National Energy Strategy. Moreover, the statutory requirement of regular submissions of national energy policy plans ensures that this framework can be modified to reflect evolving conditions, such as better knowledge of our surroundings, changes in energy markets, and advances in technology. This Strategy, then, should be thought of as a living document. Finally, this plan benefited from the comments and suggestions of numerous individuals and organizations, both inside and outside of government. The Summary of Public Comments, located at the end of this document, describes the public participation process and summarizes the comments that were received. 8 figs.

  2. Fault Management Design Strategies

    Science.gov (United States)

    Day, John C.; Johnson, Stephen B.

    2014-01-01

    Development of dependable systems relies on the ability of the system to determine and respond to off-nominal system behavior. Specification and development of these fault management capabilities must be done in a structured and principled manner to improve our understanding of these systems, and to make significant gains in dependability (safety, reliability and availability). Prior work has described a fundamental taxonomy and theory of System Health Management (SHM), and of its operational subset, Fault Management (FM). This conceptual foundation provides a basis to develop framework to design and implement FM design strategies that protect mission objectives and account for system design limitations. Selection of an SHM strategy has implications for the functions required to perform the strategy, and it places constraints on the set of possible design solutions. The framework developed in this paper provides a rigorous and principled approach to classifying SHM strategies, as well as methods for determination and implementation of SHM strategies. An illustrative example is used to describe the application of the framework and the resulting benefits to system and FM design and dependability.

  3. Genesis nature of financial strategy

    Directory of Open Access Journals (Sweden)

    O.V. Pashchenko

    2015-03-01

    Full Text Available The article is devoted to the study of the origin and history of the interpretation of the genesis of «strategy», «financial strategy», its elements and composite types. Scientists studied different views on the concept of strategy. Several specific positions founders of different approaches to define the strategy of schools operating strategies involved in the formulation and implementation of the concept of «strategy». Evaluation of different schools of strategies that deepened understanding of the industry and its strategy in the early stages of formation. Based on the works of various scholars studied by the author actually proposed interpretation of the concept strategy. The general industry and functional strategies which include the following strategies: innovation, resource, financial, production, marketing and human resources. Allocated financial strategy and its significant impact on other strategies. Author developed financial sector strategy and financial strategy of competitive enterprise. The importance of financial strategies under conditions of companies and the industry as a whole, as well as components of development of financial strategy. Deals with the factors that must be considered in the development and implementation of financial strategies. The systems analysis strategies and the impact on financial results, the estimation of their attractiveness and risk. Considered classification on the basis of financial strategies and sectoral orientation of the financial sector strategy based on company size, its form and noted the importance of this trait in systematizing strategies. The expediency of the financial strategy. Defined competitive advantage and efficiency of business and industry through the implementation of various financial strategies.

  4. Teaching Writing Strategies

    Directory of Open Access Journals (Sweden)

    Zaououi,Merbouh

    2010-03-01

    Full Text Available Developing learners’ writing skills has been of concern for a long time in education. Students studying English in our educational institutions have been found to face problems mainly in writing, making them unable to cope with the institution’s literacy expectations. However, these students may be able to develop writing skills significantly with positive instructional attitudes towards the errors they make and awareness on the teachers’ part of learner problems. That is why they should improve classroom writing instruction to address the serious problem of students writing difficult. Teaching strategies has shown a dramatic effect on the quality of students’ writing. Strategy instruction involves explicitly and systematically teaching steps necessary to use strategies independently. The following table will explain the above ideas.

  5. Strategies of Human Mating

    Directory of Open Access Journals (Sweden)

    David M. Buss

    2006-12-01

    Full Text Available Modern humans have inherited the mating strategies that led to the success of their ancestors. These strategies include long-term mating, short-term mating, extra-pair mating, mate poaching, and mate guarding. This article presents empirical evidence supporting evolution-based hypotheses about the complexities of these mating strategies. Since men and women historically confronted different adaptive problems in the mating domain, the sexes differ profoundly in evolved strategic solutions. These differences include possessing different mate preferences, different desires for short-term mating, and differences in the triggers that evoke sexual jealousy. The study of human mating is one of the “success stories” of evolutionary psychology.

  6. Bulgarian energy strategy

    International Nuclear Information System (INIS)

    2002-01-01

    The creation of a competitive energy market in Bulgaria is one of the top priorities in the government policy. To achieve this goal the following conditions are necessary: normalizing of the energy prices; financial healing; well working regulatory institutions and mechanisms; market rules and structures; appropriate legal framework. The main topics discussed in connection with the new energy strategy are: 1) General energy policy - competitive energetics; private investments and privatization; security of the energy supply, environment, energy efficiency; social protection and guarantees; 2) Sector policy - market regulation; licensing; effective use of the available power facilities; nuclear safety; 3) Gasification; 4) Heating; 5) Coal production. According to the strategy framework documents in the following aspects should be developed: integrated long-term plan 'Energetics-Environment'; price policy; market rules and structures; privatization strategies; healing programmes

  7. Compositional Advantage and Strategy

    DEFF Research Database (Denmark)

    Li, Xin

    In this paper, I first critique the composition-based view of Yadong Luo and John Child for understanding how resource-poor firms survive and thrive. To remedy the deficiencies in their perspective, I then propose a dynamic theory of compositional advantage and strategy. Here, the compositional...... advantage is redefined as the attractiveness of the composition of the producer’s offering in terms of scope and perceived value/price ratio. I identify five ways or basic compositional strategies to improve the value/price ratio. A firm may have an overall compositional strategy that is composed of some...... of the present theory to understanding Chinese firms. I conclude with managerial implications and suggestions for future research....

  8. Assessment of strategy formulation

    DEFF Research Database (Denmark)

    Acur, Nuran; Englyst, Linda

    2006-01-01

    of the success criteria through face-to-face interviews with 46 managers, workshops involving 40 managers, and two in-depth case studies. The success criteria have been slightly modified due to the empirical results, to yield the assessment tool. Findings – The resulting assessment tool integrates three generic...... approaches to strategy assessment, namely the goal-centred, comparative and improvement approaches, as found in the literature. Furthermore, it encompasses three phases of strategy formulation processes: strategic thinking, strategic planning and embedding of strategy. The tool reflects that the different......, but cases and managerial perceptions indicate that the need for accurate and detailed plans might be overrated in the literature, as implementation relies heavily on continuous improvement and empowerment. Concerning embedding, key aspects relate both to the goal-centred and improvement approaches, while...

  9. Operations Strategy in practice

    DEFF Research Database (Denmark)

    Rytter, Niels Gorm; Koch, Christian; Boer, Harry

    2005-01-01

    In this paper, we describe and illustrate a new, action-based longitudinal case study approach, which aims at helping scholars narrow the gap between the theory and practice of Operations Strategy (OS). First, we elaborate on the need for new research methods for studying OS in practice. Then, we...... and disadvantages of the method. Finally, we draw conclusions on its potential for operations strategy and operations management studies.......In this paper, we describe and illustrate a new, action-based longitudinal case study approach, which aims at helping scholars narrow the gap between the theory and practice of Operations Strategy (OS). First, we elaborate on the need for new research methods for studying OS in practice. Then, we...

  10. Requirements of modernization strategies

    International Nuclear Information System (INIS)

    Heinbuch, R.

    1997-01-01

    Instrumentation and control contributed a major share to the current level of safety, economic efficiency, and availability of the German nuclear power plants. German NPPs occupy a top position in this respect at international level, but novel instrumentation and digital control technology alone will not guarantee further enhancements. Therefore, the owner/operators established carefully devised maintenance and modernization strategies in order to safeguard their NPPs top position in the long run. The German NPPs are the most thoroughly automated plants of the world. In addition to the sweeping modernization strategies recommended by the plant manufacturers, based on computer-supported control, alternative modernization strategies have been considered in the evaluation process. This approach provides for room for maneuvre, for manufacturers as well as managers responsible for risk and cost optimization, which is a major task in view of the changing regulatory framework in the electricity market. (orig./CB) [de

  11. Power Subscription Strategy

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1998-12-21

    This document lays out the Bonneville Power Administration`s Power Subscription Strategy, a process that will enable the people of the Pacific Northwest to share the benefits of the Federal Columbia river Power System after 2001 while retaining those benefits within the region for future generations. The strategy also addresses how those who receive the benefits of the region`s low-cost federal power should share a corresponding measure of the risks. This strategy seeks to implement the subscription concept created by the Comprehensive Review in 1996 through contracts for the sale of power and the distribution of federal power benefits in the deregulated wholesale electricity market. The success of the subscription process is fundamental to BPA`s overall business purpose to provide public benefits to the Northwest through commercially successful businesses.

  12. Developing a glocalisation strategy

    DEFF Research Database (Denmark)

    Hollensen, Svend; Schimmelpfennig, Christian

    2015-01-01

    while exploiting the benefits of global integration. The challenge is to balance the local knowledge with global reach. In the case of Persil Abaya Shampoo (for the Middle East market) and Persil Black Gel (for the European market), Henkel chose a strategy that successfully benefitted from...... markets and used Persil Abayas’ particular significance in the Arab world to its advantage. The results document that it has been possible for Henkel’s Persil to gain competitive advantages in terms of higher market shares, with the ‘glocalisation strategy’ in the (Middle East) liquid detergent market.......The glocalisation strategy strives to achieve the slogan, ‘think globally but act locally’, through dynamic interdependence between headquarters and subsidiaries and/or local intermediaries around the world. Companies following such a strategy coordinate their efforts, ensuring local flexibility...

  13. Strategy under uncertainty.

    Science.gov (United States)

    Courtney, H; Kirkland, J; Viguerie, P

    1997-01-01

    At the heart of the traditional approach to strategy lies the assumption that by applying a set of powerful analytic tools, executives can predict the future of any business accurately enough to allow them to choose a clear strategic direction. But what happens when the environment is so uncertain that no amount of analysis will allow us to predict the future? What makes for a good strategy in highly uncertain business environments? The authors, consultants at McKinsey & Company, argue that uncertainty requires a new way of thinking about strategy. All too often, they say, executives take a binary view: either they underestimate uncertainty to come up with the forecasts required by their companies' planning or capital-budging processes, or they overestimate it, abandon all analysis, and go with their gut instinct. The authors outline a new approach that begins by making a crucial distinction among four discrete levels of uncertainty that any company might face. They then explain how a set of generic strategies--shaping the market, adapting to it, or reserving the right to play at a later time--can be used in each of the four levels. And they illustrate how these strategies can be implemented through a combination of three basic types of actions: big bets, options, and no-regrets moves. The framework can help managers determine which analytic tools can inform decision making under uncertainty--and which cannot. At a broader level, it offers executives a discipline for thinking rigorously and systematically about uncertainty and its implications for strategy.

  14. Optimizing decommissioning strategies

    International Nuclear Information System (INIS)

    Passant, F.H.

    1993-01-01

    Many different approaches can be considered for achieving satisfactory decommissioning of nuclear installations. These can embrace several different engineering actions at several stages, with time variations between the stages. Multi-attribute analysis can be used to help in the decision making process and to establish the optimum strategy. It has been used in the Usa and the UK to help in selecting preferred sites for radioactive waste repositories, and also in UK to help with the choice of preferred sites for locating PWR stations, and in selecting optimum decommissioning strategies

  15. Reading Comprehension Strategies

    Directory of Open Access Journals (Sweden)

    Unal Ulker

    2017-12-01

    Full Text Available The academic success of the university students greatly depends on the mastery of an academic reading skill. However, students as well as teachers, take the learning of this skill for granted, as they tend to presuppose that reading skill is acquired as a part of their secondary education. As a result, most first-year students employ non university strategies to read academic texts, which leads to a surface approach to reading and prevents students from a better understanding of the material. This paper will discuss the strategies that involve students in taking a deep approach to reading academic texts.

  16. Emergency response strategies

    International Nuclear Information System (INIS)

    Carrilo, D.; Dias de la Cruz, F.

    1984-01-01

    In the present study is estimated, on the basis of a release category (PWR4) and several accident scenarios previously set up, the emergency response efficacy obtained in the application of different response strategies on each of the above mentioned scenarios. The studied strategies contemplate the following protective measures: evacuation, shelter and relocation. The radiological response has been obtained by means of CRAC2 (Calculation of Reactor Accident Consequences) code, and calculated in terms of absorbed dose equivalent (Whole body and thyroid), as well as early and latent biological effects. (author)

  17. Editorial: Sales Strategy (2010)

    OpenAIRE

    Chris McPhee

    2010-01-01

    The editorial theme for this issue of the OSBR is Sales Strategy. While "marketing" is everything a company does to build interest in its offers, "sales" consists of converting these offers into cash. By "sales strategy," we refer to all sales planning and process development activities leading up to the actual selling of a product or service. In his recent blog post at MaRS Discovery District, Mark Zimmerman answered a question he is frequently asked by the founders of startups: "How do we f...

  18. Strategi i praksis

    DEFF Research Database (Denmark)

    Holm, Michael Jessen; Jenster, Per; Junghagen, Sven

    Præsentation af seks danske små og mellemstore virksomheder, som alle har været succesfulde inden for deres metier. Gennem en belysning af hver virksomheds strategiske situation og udviklingsinitiativer skabes et billede af hvorledes strategi praktiseres i disse virksomheder......Præsentation af seks danske små og mellemstore virksomheder, som alle har været succesfulde inden for deres metier. Gennem en belysning af hver virksomheds strategiske situation og udviklingsinitiativer skabes et billede af hvorledes strategi praktiseres i disse virksomheder...

  19. Prodrug Strategies for Paclitaxel

    Directory of Open Access Journals (Sweden)

    Ziyuan Meng

    2016-05-01

    Full Text Available Paclitaxel is an anti-tumor agent with remarkable anti-tumor activity and wide clinical uses. However, it is also faced with various challenges especially for its poor water solubility and low selectivity for the target. To overcome these disadvantages of paclitaxel, approaches using small molecule modifications and macromolecule modifications have been developed by many research groups from all over the world. In this review, we discuss the different strategies especially prodrug strategies that are currently used to make paclitaxel more effective.

  20. Dissemination and Exploitation Strategy

    DEFF Research Database (Denmark)

    Badger, Merete; Monaco, Lucio; Fransson, Torsten

    of Technology in Sweden, Politecnico di Torino in Italy, and Eindhoven University of Technology in the Netherlands. The project is partially funded by the European Commission under the 7th Framework Programme (project no. RI-283746). This report describes the final dissemination and exploitation strategy...... for project Virtual Campus Hub. A preliminary dissemination and exploitation plan was setup early in the project as described in the deliverable D6.1 Dissemination strategy paper - preliminary version. The plan has been revised on a monthly basis during the project’s lifecycle in connection with the virtual...

  1. Mobile Portal Implementation Strategy

    DEFF Research Database (Denmark)

    Gao, Ping; Damsgaard, Jan

    2005-01-01

    Mobile portal plays an important role in mobile commerce market. Current literature focuses on static analysis on the value chain of mobile portals. This article provides a dynamic perspective on mobile portal strategy. Drawing upon network economics, we describe mobile portal implementation...... as a fourphase process. In different phase, a portal provider has various challenges to overcome and adopt diverse strategies, and correspondingly the regulator has different foci. The conceptual framework proposed in this article offers a basis for further analyses on the market dynamics of mobile commerce......, and can be generalized to studying other networked technologies...

  2. Marketing Management and Strategy

    DEFF Research Database (Denmark)

    This book gives readers an understanding of the factors that shape the marketing decisions of managers who operate in African economies. It brings together fifteen African cases written by scholars and executives with rich knowledge of business practices in Africa. By combining theoretical insights...... undergraduate and graduate students in marketing, international strategy and international business who require an understanding of African business...... with practical information from the cases, the reader is introduced to issues relating to marketing strategy formulation, managerial actions in designing and implementing marketing decisions, as well as the operational contexts within which these actions are taken. The book is essential reading for both...

  3. Dissemination Strategy Report

    DEFF Research Database (Denmark)

    Badger, Merete; Kjems, Jørgen; Farinetti, Laura

    This report describes the dissemination and exploitation strategy for project Virtual Campus Hub (EU FP7 contract RI-283746). The project duration is October 2011-13 and the dissemination and exploitation plan will be revised continuously during the project’s lifecycle.......This report describes the dissemination and exploitation strategy for project Virtual Campus Hub (EU FP7 contract RI-283746). The project duration is October 2011-13 and the dissemination and exploitation plan will be revised continuously during the project’s lifecycle....

  4. Understanding Betting Strategy

    OpenAIRE

    Saha, Kanika; Lahiri, Ananya

    2017-01-01

    In this paper, we present betting strategy of a football game using probability theory. We know all betting houses offer slightly unfair odds towards the player. Here we discuss a simple way to figure out which betting house is offering relatively better odds compared to others for English Premier League. However, this methodology can be adopted for another league football match.

  5. Are Communication Strategies Teachable?

    Science.gov (United States)

    Lewis, Samantha

    2011-01-01

    This article discusses the teachability of communication strategies in the EFL classroom. As well as reflecting on the nature of speech production in the mother tongue, it looks at some of the difficulties encountered when speaking in a foreign language and the inherent difficulties in "teaching" speaking as a skill. It focuses on different types…

  6. Technology Planning Strategies

    Science.gov (United States)

    Decker, Kathy

    2004-01-01

    Effective planning strategies drive achievement of an overall technology goal to increase access to electronic information in real time in order to increase efficiency, productivity, and communication across campus. Planning relies on providing access, 'Anytime Anywhere' to student information, calendar, email, course management tools, and the…

  7. CO2-strategier

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard

    2008-01-01

    I 2007 henvendte Lyngby-Taarbæk kommunens Agenda 21 koordinator sig til Videnskabsbutikken og spurgte om der var interesse for at samarbejde om CO2-strategier. Da Videnskabsbutikken DTU er en åben dør til DTU for borgerne og deres organisationer, foreslog Videnskabsbutikken DTU at Danmarks...

  8. Terrorism and Investigation Strategies

    OpenAIRE

    Muhammad Mustofa

    2005-01-01

    This paper discussed that, for successful implementation of the strategies in investigating terrorism, besides requiring professional skilled investigators, there are some additional requirements that need to be fulfilled. Effective and long term prevention of terrorism should be directed towards producing good social welfare and to minimize every condition that may be conducive to the emergence of terrorism, such as discrimination and marginalization.

  9. Management strategies for fibromyalgia

    Directory of Open Access Journals (Sweden)

    Le Marshall KF

    2011-07-01

    Full Text Available Kim Francis Le Marshall, Geoffrey Owen LittlejohnDepartments of Rheumatology and Medicine, Monash Medical Centre and Monash University, Victoria, AustraliaDate of preparation: 14 June 2011Clinical question: What are the effective, evidence-based strategies available for the management of fibromyalgia?Conclusion: There are a number of management strategies available with robust evidence to support their use in clinical practice.Definition: Fibromyalgia is a complex pain syndrome characterized by widespread, chronic muscular pain and tenderness, disordered sleep, emotional distress, cognitive disturbance, and fatigue. Its prevalence is estimated to be 3%–5% in the population and higher yet in patients with comorbid rheumatic diseases.Level of evidence: Systematic reviews, meta-analyses, randomized controlled trials (RCTs.Search sources: PubMed, Cochrane Library, manual searchConsumer summary: Key messages for patients and clinicians are:1. There are many effective pharmacological management strategies available for fibromyalgia.2. A nonpharmacological, multicomponent approach utilizing education, aerobic exercise, psychological therapy, and other strategies is also effective for fibromyalgia.3. Despite the significant and, at times, disabling physical and psychological symptoms, fibromyalgia can be a manageable condition with a potentially good outcome.Keywords: fibromyalgia, pain, treatment, management, evidence 

  10. Delta hedging strategies comparison

    DEFF Research Database (Denmark)

    De Giovanni, Domenico; Ortobelli, S.; Rachev, S.T.

    2008-01-01

    In this paper we implement dynamic delta hedging strategies based on several option pricing models. We analyze different subordinated option pricing models and we examine delta hedging costs using ex-post daily prices of S&P 500. Furthermore, we compare the performance of each subordinated model...

  11. Resilient Grid Operational Strategies

    Energy Technology Data Exchange (ETDEWEB)

    Pasqualini, Donatella [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-01

    Extreme weather-related disturbances, such as hurricanes, are a leading cause of grid outages historically. Although physical asset hardening is perhaps the most common way to mitigate the impacts of severe weather, operational strategies may be deployed to limit the extent of societal and economic losses associated with weather-related physical damage.1 The purpose of this study is to examine bulk power-system operational strategies that can be deployed to mitigate the impact of severe weather disruptions caused by hurricanes, thereby increasing grid resilience to maintain continuity of critical infrastructure during extreme weather. To estimate the impacts of resilient grid operational strategies, Los Alamos National Laboratory (LANL) developed a framework for hurricane probabilistic risk analysis (PRA). The probabilistic nature of this framework allows us to estimate the probability distribution of likely impacts, as opposed to the worst-case impacts. The project scope does not include strategies that are not operations related, such as transmission system hardening (e.g., undergrounding, transmission tower reinforcement and substation flood protection) and solutions in the distribution network.

  12. Evolutionary Stable Strategy

    Indian Academy of Sciences (India)

    IAS Admin

    Biologists refer to this as a 'limited war' or conventional (ritualistic) strategy (not ... Now allow us to explain a few things about cat behaviour, which will help .... getting injured, but it also helped save both energy and time, vital .... intelligent and.

  13. Thermal reactor strategy

    International Nuclear Information System (INIS)

    1981-01-01

    This statement sets down briefly the CEGB's views on the requirement for nuclear power and outlines current progress in the implementation of the CEGB's thermal reactor strategy. The programme is traced historically, together with statements of Government policy. The place of Magnox, AGR, SGHWR, PWR and fast breeder reactors is discussed. Advantages and problems associated with the various types are outlined. (U.K.)

  14. When Strategy Ends

    DEFF Research Database (Denmark)

    Vestenskov, David; Jørgensen, Lars Wille

    2014-01-01

    This chapter deals with the end of strategy, that is, conflict termination and how strategic achievements are measured and evaluated. It claims that the modern intervention of choice by NATO and its allies are transformation wars and challenges the concept of victory in such wars. Through a compa...

  15. Evolutionary Stable Strategy

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 21; Issue 9. Evolutionary Stable Strategy: Application of Nash Equilibrium in Biology. General Article Volume 21 Issue 9 September 2016 pp 803- ... Keywords. Evolutionary game theory, evolutionary stable state, conflict, cooperation, biological games.

  16. Inflation Protected Investment Strategies

    Directory of Open Access Journals (Sweden)

    Mirco Mahlstedt

    2016-03-01

    Full Text Available In this paper, a dynamic inflation-protected investment strategy is presented, which is based on traditional asset classes and Markov-switching models. Different stock market, as well as inflation regimes are identified, and within those regimes, the inflation hedging potential of stocks, bonds, real estate, commodities and gold are investigated. Within each regime, we determine optimal investment portfolios driven by the investment idea of protection from losses due to changing inflation if inflation is rising or high, but decoupling the performance from inflation if inflation is low. The results clearly indicate that these asset classes behave differently in different stock market and inflation regimes. Whereas in the long-run, we agree with the general opinion in the literature that stocks and bonds are a suitable hedge against inflation, we observe for short time horizons that the hedging potential of each asset class, especially of real estate and commodities, depend strongly on the state of the current market environment. Thus, our approach provides a possible explanation for different statements in the literature regarding the inflation hedging properties of these asset classes. A dynamic inflation-protected investment strategy is developed, which combines inflation protection and upside potential. This strategy outperforms standard buy-and-hold strategies, as well as the well-known 1 N -portfolio.

  17. The generic strategy trap.

    Science.gov (United States)

    Miller, D

    1992-01-01

    Management experts claim that for a company to thrive, it must concentrate on a single generic strategy--on one thing it does better than its rivals. But specialization also has its disadvantages. The author suggests that a broader, mixed approach may be preferable.

  18. Comprehension Strategy Gloves.

    Science.gov (United States)

    Newman, Gayle

    2002-01-01

    Describes the idea of creating a glove for each of the comprehension strategies for use with different text structures. Notes that the gloves serve as a multisensory approach by providing visual clues through icons on each finger and the palm. Discusses three different gloves: the prereading glove, the narrative text structure glove, and the…

  19. The EU's Biofuel Strategy

    International Nuclear Information System (INIS)

    2006-01-01

    The EU is supporting biofuels, with the aim of reducing greenhouse-gas emission, encouraging the decarbonisation of fuels used in transportation, diversifying energy procurement, offering new earning opportunities in rural areas, and developing long-term replacements for oil. We publish lengthy excerpts from the recent Communication, COM(2006) 34def. which describes the strategy adopted by the Commission [it

  20. Behavioural strategy: Adaptability context

    Directory of Open Access Journals (Sweden)

    Piórkowska Katarzyna

    2016-05-01

    Full Text Available The paper is embedded in the following fields: strategic management in terms of behavioural strategy concept, adaptability construct, and micro-foundations realm as well as organizational theory and psychology. Moreover, the paper concerns to some extent a multi-level approach in strategic management involving individual, team, and organizational level. The aim of the paper is to contribute to extend, on one hand, the ascertainment set in the field of behavioural strategy as behavioural strategy encompasses a mindboggling diversity of topics and methods and its conceptual unity has been hard to achieve (Powell, Lovallo, Fox 2011, p. 1371, and on the other hand, to order mixed approaches to adaptability especially to gain insights on micro-level adapting processes (individual adaptability and adaptive performance in terms of the multi-level approach. The method that has been used is literature studies and the interference is mostly deductive. The structure of the manuscript is four-fold. The first part involves the considerations in the field of adaptability and adaptive performance at the individual level. The issues of adaptability and adaptive performance at the team level have been presented in the second part. The third part encompasses the organizational adaptability assertions. Finally, the conclusion, limitations of the considerations highlighted as well as the future research directions have been emphasized. The overarching key finding is that the behavioural strategy concept may constitute the boundary spanner in exploring and explaining adaptability phenomenon at different levels of analysis.

  1. Towards effective learning strategies

    NARCIS (Netherlands)

    Bergstra, Anouk Simone

    2015-01-01

    To become self-regulative in learning, students should be able to deploy various learning strategies in a flexible way. For this, they require specific knowledge and skills, referred to as metacognition. Metacognition is a complex concept that is difficult for teachers to teach to their students.

  2. INOVASI DAN STRATEGI PENCAPAIANNYA

    Directory of Open Access Journals (Sweden)

    Liem Ferryanto

    2009-01-01

    Full Text Available Innovation is the way of life of any institution to profitably sustain its life. It starts with empathy, the ability to reach outside of ourselves and walk in someone else’s shoes, and optimal implementation of the newly advanced technology. Innovation shows its results through continuously hard working efforts known as "10 Thousand Hours Rule". As world uncertainty creates complexity we, instead of predicting, should therefore anticipate the future by creating and managing real options on contingent projects or elements of alternative optimal strategies. This should reflect into our portfolio strategy. Abstract in Bahasa Indonesia: Inovasi merupakan darah bagi suatu institusi untuk bisa hidup berkelanjutan serta menguntungkan. Inovasi berupa penemuan baru secara sistematis yang berawal dari empati, kemampuan untuk melihat dunia melalui mata orang lain, dan pemanfaatan secara optimal kemajuan teknologi yang ada. Inovasi baru menghasilkan buahnya melalui kerja keras, yaitu dengan mengikuti “Aturan 10 Ribu Jam” secara berkesinambungan. Ketidakpastian, interaksi, keterbatasan dan degradasi menciptakan kompleksitas tentang kebutuhan dan solusi di masa depan. Oleh sebab itu daripada meramalkan risiko yang bakal terjadi, kita sebaiknya memasang strategi berupa skenario untuk mereduksi akibat dari risiko masa depan yang tidak kita mengerti. Skenario ini dapat diperoleh lewat penciptaan dan penanganan beberapa pilihan nyata atas semua proyek antisipatif yang ada. Kata kunci: Inovasi, ketidakpastian dan kompleksitas, aturan 10 ribu jam, paradoks strategi, peta jalan, empati, kerja berkesinambungan.

  3. NASA science communications strategy

    Science.gov (United States)

    1995-01-01

    In 1994, the Clinton Administration issued a report, 'Science in the National Interest', which identified new national science goals. Two of the five goals are related to science communications: produce the finest scientists and engineers for the 21st century, and raise scientific and technological literacy of all Americans. In addition to the guidance and goals set forth by the Administration, NASA has been mandated by Congress under the 1958 Space Act to 'provide for the widest practicable and appropriate dissemination concerning its activities and the results thereof'. In addition to addressing eight Goals and Plans which resulted from a January 1994 meeting between NASA and members of the broader scientific, education, and communications community on the Public Communication of NASA's Science, the Science Communications Working Group (SCWG) took a comprehensive look at the way the Agency communicates its science to ensure that any changes the Agency made were long-term improvements. The SCWG developed a Science Communications Strategy for NASA and a plan to implement the Strategy. This report outlines a strategy from which effective science communications programs can be developed and implemented across the agency. Guiding principles and strategic themes for the strategy are provided, with numerous recommendations for improvement discussed within the respective themes of leadership, coordination, integration, participation, leveraging, and evaluation.

  4. Modeling and Interrogative Strategies.

    Science.gov (United States)

    Denney, Douglas R.

    Three studies to determine the effects of adult models on interrogative strategies of children (ages 6-11) are reviewed. Two issues are analyzed: (1) the comparative effectiveness of various types of modeling procedures for changing rule-governed behaviors, and (2) the interaction between observational learning and the developmental level of the…

  5. The Seven Step Strategy

    Science.gov (United States)

    Schaffer, Connie

    2017-01-01

    Many well-intended instructors use Socratic or leveled questioning to facilitate the discussion of an assigned reading. While this engages a few students, most can opt to remain silent. The seven step strategy described in this article provides an alternative to classroom silence and engages all students. Students discuss a single reading as they…

  6. Gazprom: Russia's strategy

    International Nuclear Information System (INIS)

    Lizin, A.M.; Zeisler, N.

    2007-01-01

    Seventeen years after the splitting up of the Soviet empire, Russia is looking again for huge international ambitions. Its main advantage in this power search will is its energy resources. Production area, but also transit area between Asia, central Asia, Caucasus and Europe, Russia is an inevitable partner and wishes to take advantage of this strategic position. Gazprom, the hugest gas company in the world, is totally under the control of the government. Therefore, the Kremlin has made gas its main political and diplomatic weapon. Such an energetic imperialisms has strong economical and political consequences on the rest of Europe as illustrated by the recent Ukrainian crisis. The reconstruction of an energy empire similar to the one of the hottest days of the cold war worries also the USA. This study is a collective work carried out by students of the Sciences Po school of Paris in the framework of the 'international organizations' seminar given by by A.M Lizin, president of the Belgium senate and chairwoman of the human rights commission of the organization for European security and cooperation. Content: Gazprom's international strategy, Gazprom: an omnipotent gas company, Gazprom's international strategy at the service of the Russian foreign policy, Gazprom's energy stake and strategies, Gazprom and Armenia, Gazprom and Azerbaijan, Gazprom and Belgium, Gazprom and Bielorussia, Gazprom and Iberia, French position in energy stakes and in front of Gazprom, Gazprom's difficulties in Hungary, Uzbekistan and Kyrgyzstan in front of Gazprom, Gazprom and the US strategy. (J.S.)

  7. Sensemaking and strategy

    DEFF Research Database (Denmark)

    Nielsen, Renate

    of these processes my focus will be on how sensemaking processes are transformed into strategy and policies to be applied in daily routines. This way, I believe, we can learn more about how organisations develop and use this knowledge to gain further competitiveness. I will look at these processes on various...

  8. Price strategy and pricing strategy: terms and content identification

    Directory of Open Access Journals (Sweden)

    Panasenko Tetyana

    2015-11-01

    Full Text Available The article is devoted to the terminology and content identification of seemingly identical concepts "price strategy" and "pricing strategy". The article contains evidence that the price strategy determines the direction, principles and procedure of implementing the company price policy and pricing strategy creates a set of rules and practical methods of price formation in accordance with the pricing strategy of the company.

  9. Income generation strategy in the overall hierarchy of business strategy

    Directory of Open Access Journals (Sweden)

    S.V. Shastun

    2015-03-01

    Full Text Available To comply with claims of a modern economy significantly increases the role of strategic revenue management in enterprises, and in the first place, strategic management of income generation. The concept of an income generation strategy is not disclosed in the scientific literature, in this connection in article describes and analyzes the main concepts which are similar in content to the category of income generation strategy of enterprises (strategy analysis of income, revenue strategy, development strategy of income. Defines the role and importance of income generation strategy in modern management practices and presented the author's definition of income generation strategy. In article considered income generation strategy a compared to financial strategy of the enterprise and proved the difference between them. Show the position of income generation strategy in the hierarchy of strategies of enterprises and spheres of influence at all levels of the company. Income generation strategy described as interlevel, components of which are elements of all the functional and resource strategies and established a direct and feedback between the income generation strategy and corporate, competitive, functional and resource strategy.

  10. Five types of organizational strategy

    DEFF Research Database (Denmark)

    Steensen, Elmer Fly

    2014-01-01

    Models in the strategy field defining the strategy concept emphasize schools of thought or strategy perspectives, but not how to define the idiosyncratic composition of an organization’s strategy content. Based on a literature review in which meanings have been attached to the concept, this paper...... presents a new model including five types of organizational strategy. The model emphasizes that key influencers may make heterogeneous contributions to an organization’s strategy and also that significant effects may result from interaction between types of strategy....

  11. Strategy of technology and innovation

    International Nuclear Information System (INIS)

    Kim, Yeon Min

    1998-10-01

    This book introduces strategy of technology and innovation which includes design and development of strategy of technology, performance of strategy of technology and building and practice of strategy of development. The contents of this book are form of industrial innovation, act in strategy, advantage of technical innovation, new perspective of studying and innovation, alliance with competitor, cost of transmission and innovation, learning cycle of new product and power of consistency of product.

  12. Probability matching and strategy availability

    OpenAIRE

    J. Koehler, Derek; Koehler, Derek J.; James, Greta

    2010-01-01

    Findings from two experiments indicate that probability matching in sequential choice arises from an asymmetry in strategy availability: The matching strategy comes readily to mind, whereas a superior alternative strategy, maximizing, does not. First, compared with the minority who spontaneously engage in maximizing, the majority of participants endorse maximizing as superior to matching in a direct comparison when both strategies are described. Second, when the maximizing strategy is brought...

  13. Editorial: Sales Strategy (2010

    Directory of Open Access Journals (Sweden)

    Chris McPhee

    2010-09-01

    Full Text Available The editorial theme for this issue of the OSBR is Sales Strategy. While "marketing" is everything a company does to build interest in its offers, "sales" consists of converting these offers into cash. By "sales strategy," we refer to all sales planning and process development activities leading up to the actual selling of a product or service. In his recent blog post at MaRS Discovery District, Mark Zimmerman answered a question he is frequently asked by the founders of startups: "How do we find a good sales person?" In short, his answer is "Don't." This is not meant as a slight to sales professionals, but rather, Zimmerman is advocating that companies should not equate having sales professionals to having a sales strategy. Sales professionals have a critical role to play in a company's success, but they are being given an impossible task if asked to sell something that has not been validated with customers. Zimmerman explains that sales professionals should be hired only once a company has validated that the value proposition resonates with customers and that the sales model will be effective. This lesson also applies to established companies, where existing sales staff require this same foundation to be effective. So how does a company determine whether its value proposition resonates with customers? The answer, of course, is to talk to customers. In the OSBR and elsewhere, the need for early customer input is a dominant theme in recent discussions of product development, marketing, and now sales strategy. By talking to customers, listening to how they describe their needs, and interpreting how their needs could be met, a value proposition can tested and refined. It is far more efficient and effective to iteratively refine a value proposition before attempting to sell than to attempt a salvage operation in response to slumping sales. Customer input is also a critical ingredient in developing an effective sales strategy. In this issue of the

  14. CELEBRITY ENDORSEMENT STRATEGY

    Directory of Open Access Journals (Sweden)

    CHIOSA ANA RALUCA

    2012-09-01

    Full Text Available Brands ofen use celebrities to get impact, because they are seen by the public as credible source of informationabout product or company. People aspire to the values and lifestyles of celebrities. Consumers selectively integrateperceived values and behavior of celebrities they admire, to build and communicate their own identity.Celebrity endorser is a person who enjoys high reputation and prestige, beeing known to most people. Celebrityendorsement is a relevant strategy for the product categories which improve the image (such as fashion, perfumes orcosmetics.This paper presents types, techniques and models of analysing celebrities’ efficiency in endorsingbrands/products. Celebrity endorsement has become one of the communication strategies used in marketing to buildcongruence between brand image and consumers. Famous persons exert their influence on consumer throughperceived attributes such as expertise, trustworthiness, attractiveness, familiarty and likeability.

  15. Corporate Climate Strategies

    DEFF Research Database (Denmark)

    Bjarnø, Ole-Christian; Maltha, Jonas

    2003-01-01

    at establishing operational guidelines for energy-intensive industries to navigate and gain competitive advantages in a diverse and risky business environment. Based on a literature study of strategic environmental management and carbon management, this article aims to establish such guidelines for corporate......Since the 1997 Kyoto Protocol on Climate Change outlined the first embryonic plans for an emissions market, a significant uncertainty about the value on carbon, in concert with a swift development in energy business, has brought about the concept of carbon management. Carbon management aims...... strategic carbon management for medium to large companies with greenhouse gas intensive activities. The guideline framework is established on the basis of a generic strategy structure in which the factors influencing corporate climate strategies are identified. It is concluded that there is little rationale...

  16. Mechanical ventilation strategies.

    Science.gov (United States)

    Keszler, Martin

    2017-08-01

    Although only a small proportion of full term and late preterm infants require invasive respiratory support, they are not immune from ventilator-associated lung injury. The process of lung damage from mechanical ventilation is multifactorial and cannot be linked to any single variable. Atelectrauma and volutrauma have been identified as the most important and potentially preventable elements of lung injury. Respiratory support strategies for full term and late preterm infants have not been as thoroughly studied as those for preterm infants; consequently, a strong evidence base on which to make recommendations is lacking. The choice of modalities of support and ventilation strategies should be guided by the specific underlying pathophysiologic considerations and the ventilatory approach must be individualized for each patient based on the predominant pathophysiology at the time. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Hybrid strategies in nanolithography

    Energy Technology Data Exchange (ETDEWEB)

    Saavedra, Hector M; Mullen, Thomas J; Zhang Pengpeng; Dewey, Daniel C; Claridge, Shelley A; Weiss, Paul S [Department of Chemistry, The Pennsylvania State University, University Park, PA 16802 (United States)], E-mail: psw@cnsi.ucla.edu

    2010-03-15

    Hybrid nanoscale patterning strategies combine the registration and addressability of conventional lithographic techniques with the chemical and physical functionality enabled by intermolecular, electrostatic and/or biological interactions. This review aims to highlight and to provide a comprehensive description of recent developments in hybrid nanoscale patterning strategies that enhance existing lithographic techniques or can be used to fabricate functional chemical patterns that interact with their environment. These functional structures create new capabilities, such as the fabrication of physicochemical surfaces that can recognize and capture analytes from complex liquid or gaseous mixtures. The nanolithographic techniques we describe can be classified into three general areas: traditional lithography, soft lithography and scanning-probe lithography. The strengths and limitations of each hybrid patterning technique will be discussed, along with the current and potential applications of the resulting patterned, functional surfaces.

  18. Canadian hydrogen strategies

    International Nuclear Information System (INIS)

    Fairlie, M.; Scepanovic, V.; Dube, J.; Hammerli, M.; Taylor, J.

    2004-01-01

    'Full text:' In May of 2004, industry and government embarked on a process to create a strategic plan for development of the 'hydrogen economy' in Canada. The process was undertaken to determine how the development and commercialization of hydrogen technologies could be accelerated to yield a 'visible' reduction in greenhouse gases within the timeframe of Kyoto, while establishing a direction that addresses the necessity of far greater reductions in the future. Starting with a meeting of twenty seven experts drawn from the hydrogen technology, energy and transportation industries and government, a vision and mission for the planning process was developed. Two months later a second meeting was held with a broader group of stakeholders to develop hydrogen transition strategies that could achieve the mission, and from identifying the barriers and enablers for these strategies, an action plan was created. This paper reviews the results from this consultation process and discusses next steps. (author)

  19. Exit-strategies

    DEFF Research Database (Denmark)

    Mørck, Line Lerche; Palm, Anne-Mette; Sys Møller-Andersen, Camilla

    different empirical sources. To develop and extend an "exit-prototype" about conditions of importance for moving beyond a gang/criminal position, we have analyzed documents (from newspapers and books), involved ex-gang members, social workers and experts as co-researchers in interviews, "gang......This paper is about exit-strategies, constructing a theoretical and empirical informed analysis of current societal conditions that influence motor cycle gangs such as Hells Angels or Bandidos and other ‘wild' youth' possibilities and limitations for moving beyond criminal activities. We especially...... focus on the involved communities in the current Danish gang-conflict, which escalated with deadly killings in 2008, and thereby became a so called "gang-war". We will start out presenting different practice notions of exit, and we will extend and discuss understandings of "exit-strategies" by analyzing...

  20. COINCO - Strategy 2025

    DEFF Research Database (Denmark)

    Jespersen, Per Homann; Jensen, Anne; Lundgaard, Jacob

    2007-01-01

    InvestitionsBank des Landes Brandenburg   The regions and cities in the COINCO-corridor Oslo-Göteborg-Malmö-Copenhagen-Berlin have worked out a COINCO Strategy 2025 for becoming one of the world's most competitive regions. Behind this strategy is a political will to utilize mutual strengths and together become....... Therefore a number of knowledge institutions have to be ormed organized around the ‘triple helix'-principle - a tight collaboration between business, administration and knowledge producers, especially universities. Also new ways of collaboration have to be explored - ‘network governance' has to be developed......The group of COINCO Partners Københavns Kommune (Lead partner) Bornholms Regionskommune Oslo Kommune Østfold Fylkeskommune Akershus Fylkeskommune Business Region Göteborg AB Region Skåne Malmö Stad Lund Kommune Landskrona Kommune Helsingborg Kommune Region Halland Region Västra Götaland...

  1. Nuclear fuel strategies

    International Nuclear Information System (INIS)

    Rippon, S.

    1989-01-01

    The paper reports on two international meetings on nuclear fuel strategies, one organised by the World Nuclear Fuel Market in Seville (Spain) October 1988, and the other organised by the American and European nuclear societies in Washington (U.S.A.) November 1988. At the Washington meeting a description was given of the uranium supply and demand market, whereas free trade in uranium was considered in Seville. Considerable concern was expressed at both meetings on the effect on the uranium and enrichment services market of very low prices for spot deals being offered by China and the Soviet Union. Excess enrichment capacity, the procurement policies of the USA and other countries, and fuel cycle strategies, were also discussed. (U.K.)

  2. Modern Competitive Strategy Firm

    Directory of Open Access Journals (Sweden)

    František Bartes

    2010-01-01

    Full Text Available The article deals with problems of an ever increasing number of cases of successful application of old combat strategies in business practice. Nevertheless, the author refuses the so called “direct conflict“ of firms, when it is really fought for victory on the market. His approach is based on the philosophy of “victory without fight“, in other words – of achieving the aim without direct conflict with the rival firm.In the end he comes to the conclusion that combat philosophies are more and more often incorporated into classical approach of strategic firm control and become the integral part of philosophy of management. At the close happens to opinion that the one from basic factors absolutely necessary to creation such strategy at company, is necessary present so-called „creative intelligence“.

  3. SPORT MARKETING MIX STRATEGIES

    OpenAIRE

    Alexandru Lucian MIHAI

    2013-01-01

    This paper presents a brief overview of a significant element of the sport marketing management model called the marketing mix. The marketing mix is crucial because it defines the sport business, and much of the sport marketer’s time is spent on various functions within the marketing mix. The marketing mix is the strategic combination of the product, price, place and promotion elements. These elements are typically called the four Ps of marketing. Decisions and strategies for each are importa...

  4. CELEBRITY ENDORSEMENT STRATEGY

    OpenAIRE

    CHIOSA ANA RALUCA

    2012-01-01

    Brands ofen use celebrities to get impact, because they are seen by the public as credible source of information about product or company. People aspire to the values and lifestyles of celebrities. Consumers selectively integrate perceived values and behavior of celebrities they admire, to build and communicate their own identity. Celebrity endorser is a person who enjoys high reputation and prestige, beeing known to most people. Celebrity endorsement is a relevant strategy for the product ca...

  5. Vaccine strategies: Optimising outcomes.

    Science.gov (United States)

    Hardt, Karin; Bonanni, Paolo; King, Susan; Santos, Jose Ignacio; El-Hodhod, Mostafa; Zimet, Gregory D; Preiss, Scott

    2016-12-20

    Successful immunisation programmes generally result from high vaccine effectiveness and adequate uptake of vaccines. In the development of new vaccination strategies, the structure and strength of the local healthcare system is a key consideration. In high income countries, existing infrastructures are usually used, while in less developed countries, the capacity for introducing new vaccines may need to be strengthened, particularly for vaccines administered beyond early childhood, such as the measles or human papillomavirus (HPV) vaccine. Reliable immunisation service funding is another important factor and low income countries often need external supplementary sources of finance. Many regions also obtain support in generating an evidence base for vaccination via initiatives created by organisations including World Health Organization (WHO), the Pan American Health Organization (PAHO), the Agence de Médecine Préventive and the Sabin Vaccine Institute. Strong monitoring and surveillance mechanisms are also required. An example is the efficient and low-cost approaches for measuring the impact of the hepatitis B control initiative and evaluating achievement of goals that have been established in the WHO Western Pacific region. A review of implementation strategies reveals differing degrees of success. For example, in the Americas, PAHO advanced a measles-mumps-rubella vaccine strategy, targeting different population groups in mass, catch-up and follow-up vaccination campaigns. This has had much success but coverage data from some parts of the region suggest that children are still not receiving all appropriate vaccines, highlighting problems with local service infrastructures. Stark differences in coverage levels are also observed among high income countries, as is the case with HPV vaccine implementation in the USA versus the UK and Australia, reflecting differences in delivery settings. Experience and research have shown which vaccine strategies work well and the

  6. Hand hygiene strategies

    OpenAIRE

    Yazaji, Eskandar Alex

    2011-01-01

    Hand hygiene is one of the major players in preventing healthcare associated infections. However, healthcare workers compliance with hand hygiene continues to be a challenge. This article will address strategies to help improving hand hygiene compliance. Keywords: hand hygiene; healthcare associated infections; multidisciplinary program; system change; accountability; education; feedback(Published: 18 July 2011)Citation: Journal of Community Hospital Internal Medicine Perspectives 2011, 1: 72...

  7. Competitive strategy : Sorrin Puutarha

    OpenAIRE

    Haaristo, Emilia

    2010-01-01

    The thesis handles the fresh food product industry in Finland and especially one company operating in the industry and its competitive position. Sorrin Puutarha manufactures ready-to-use fresh cut salad bag, which is sold in the grocery stores. The objective of the thesis was to find competitive advantages of the case company. Once the competitive advantages were identified the purpose was to choose a fitting competitive strategy that would strengthen those advantages. The field study was con...

  8. Intelligent National Strategy

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    China has unveiled a strategic plan aimed at strengthening I PR protection and enhancing the country’s overall competitiveness China’s State Council published the Outline of the National Intellectual Property Strategy in early June, taking on one of the country’s major bugbears. The plan aims to improve the use of intellectual property rights (IPR) by 2020 and consists of a preface, guiding prin- ciples and strategic goals, strategic focuses,

  9. Implementing acquisition strategies

    International Nuclear Information System (INIS)

    Montgomery, G. K.

    1997-01-01

    The objective of this paper is to address some of the strategies necessary to effect a successful asset or corporate acquisition. Understanding the corporate objective, the full potential of the asset, the specific strategies to be employed, the value of time, and most importantly the interaction of all these are crucial, for missed steps are likely to result in missed opportunities. The amount of factual information that can be obtained and utilized in a timely fashion is the largest single hurdle to the capture of value in the asset or corporate acquisition. Fact, familiarity and experience are key in this context. The importance of the due diligence process prior to title or data transfer cannot be overemphasized. Some of the most important assets acquired in a merger may be the people. To maximize effectiveness, it is essential to merge both existing staff and those that came with the new acquisition as soon as possible. By thinking together as a unit, knowledge and experience can be applied to realize the potential of the asset. Hence team building is one of the challenges, doing it quickly is usually the most effective. Developing new directions for the new enlarged company by combining the strengths of the old and the new creates more value, as well as a more efficient operation. Equally important to maximizing the potential of the new acquisition is the maintenance of the momentum generated by the need to grow that gave the impetus to acquiring new assets in the first place. In brief, the right mix of vision, facts and perceptions, quick enactment of the post-close strategies and keeping the momentum alive, are the principal ingredients of a focused strategy

  10. Real Time Strategy Language

    OpenAIRE

    Hayes, Roy; Beling, Peter; Scherer, William

    2014-01-01

    Real Time Strategy (RTS) games provide complex domain to test the latest artificial intelligence (AI) research. In much of the literature, AI systems have been limited to playing one game. Although, this specialization has resulted in stronger AI gaming systems it does not address the key concerns of AI researcher. AI researchers seek the development of AI agents that can autonomously interpret learn, and apply new knowledge. To achieve human level performance, current AI systems rely on game...

  11. The Nuclear Strategy Tripod

    DEFF Research Database (Denmark)

    Nellemann, Camilla

    in the Saudia Arabia. I find coopetitive behavior; vertical integration; technology; market-political ambidexterity; energy policy; industrial policy; and security policy to be the most important factors. My research extends Peng et al.’s (2009) strategy tripod by adding variables that enable it to analyze...... nuclear reactor manufacturers. In a future study, it is relevant to test my hypotheses using a larger sample size....

  12. Greenhouse gas strategy

    International Nuclear Information System (INIS)

    2001-03-01

    Because the overall effects of climate change will likely be more pronounced in the North than in other parts of the country, the Government of the Northwest Territories considers it imperative to support global and local actions to reduce greenhouse gas emissions. Government support is manifested through a coordinating role played by senior government representatives in the development of the NWT Greenhouse Gas Strategy, and by participation on a multi-party working committee to identify and coordinate northern actions and to contribute a northern perspective to Canada's National Climate Change Implementation Strategy. This document outlines the NWT Government's goals and objectives regarding greenhouse gas emission reduction actions. These will include efforts to enhance awareness and understanding; demonstrate leadership by putting the Government's own house in order; encouraging action across sectors; promote technology development and innovation; invest in knowledge and building the foundation for informed future decisions. The strategy also outlines the challenges peculiar to the NWT, such as the high per person carbon dioxide emissions compared to the national average (30 tonnes per person per year as opposed to the national average of 21 tonnes per person per year) and the increasing economic activity in the Territories, most of which are resource-based and therefore energy-intensive. Appendices which form part of the greenhouse gas strategy document, provide details of the potential climate change impact in the NWT, a detailed explanation of the proposed measures, an emission forecast to 2004 from industrial processes, fuel combustion and incineration, and a statement of the official position of the Government of the NWT on climate change

  13. Optimal intermittent search strategies

    International Nuclear Information System (INIS)

    Rojo, F; Budde, C E; Wio, H S

    2009-01-01

    We study the search kinetics of a single fixed target by a set of searchers performing an intermittent random walk, jumping between different internal states. Exploiting concepts of multi-state and continuous-time random walks we have calculated the survival probability of a target up to time t, and have 'optimized' (minimized) it with regard to the transition probability among internal states. Our model shows that intermittent strategies always improve target detection, even for simple diffusion states of motion

  14. Pure National Security Strategy

    Science.gov (United States)

    2011-06-01

    gd1ne997g1lu3p7d&size=largest Berlin, Isaiah . Four Essays on Liberty. New York, NY: Oxford University Press, 1970. Bijker, Wiebe E., Thomas P. Hughes and...of the first scientists to formalize what has long been known to kings and emperors is American economist Thomas C. Schelling. In his influential...Robert Pape simplifies the mechanism where coercion affects 45 Schelling, Thomas C. The Strategy of

  15. Strategi Pengembangan Pariwisata Lokal

    OpenAIRE

    Suryani, Ade Irma

    2016-01-01

    Development of the tourism sector is expected to provide benefits to the community, because the tourism sector is one of the sectors of economic development. Tourism activity is one of the non-oil sector is expected to provide a substantial contribution to the economy Negara.Strategis pengebangan tourism in rural areas, namely by taking into account the advice and the existing infrastructure and the application of the stepping tourism. Tourism facilities can be divided into three parts, namel...

  16. PREPARING A MARKETING STRATEGY

    OpenAIRE

    Grönholm, Eija

    2010-01-01

    The objective of this thesis was to prepare a marketing strategy for Living City Centre of Kotka Association. The work was implemented with the members of the association and the executive director Reijo Saksa. Living City Centre of Kotka Association was founded in spring 2006 for promoting living, enjoyable and safe centers in the City of Kotka. The association has two permanent employees. The main duties are managing the Kotka market places and promoting the stakeholder connections betw...

  17. Hotel Marketing Strategy

    OpenAIRE

    Hykšová, Vendula

    2010-01-01

    The Master's Thesis is focused on the hotel marketing strategy issue. The theoretical section summarizes information about an issue of strategic situation analysis and it also involves marketing tools with focus on the hotel and spa industry. The goal of this paper is to design the situation analysis, evaluate the marketing tools used by the hotel and then summarize the results and include suggestions for the analyzed hotel. For the thesis were used literature sources as well as statistical y...

  18. Strategy of technical innovation

    International Nuclear Information System (INIS)

    Lee, Ga Jong

    1990-12-01

    This book deals with policy of scientific technique and technical innovation such as research for development and types of technical innovation, historical development and process of technical innovation, economic growth, technology change and investment for research and development, structure and form of technical transfer with the meaning process, from, structure and theory, economic growth and investment of research and development with experiential analysis and case study on strategy of technical innovation in electron and fine chemical industry.

  19. Opaque Nuclear Strategy

    Science.gov (United States)

    2017-12-01

    Relationship, 0000271219, 1961. https://www.cia.gov/ library / readingroom/docs/DOC_0000271219.pdf. . Trends in South Africa’s Nuclear Security Policies ...official policy or position of the Department of Defense or the U.S. Government. IRB number ____N/A____. 12a. DISTRIBUTION / AVAILABILITY STATEMENT...how Israel and South Africa shaped those strategies. This research may contribute to better understanding possible policies of potential nuclear

  20. Public relations strategy

    International Nuclear Information System (INIS)

    Kukovica, T.; Mele, I.

    1996-01-01

    NIMBY (Not In My Back Yard) syndrome has become a major problem in the field of environmental planning. Also in Slovenia. Agency for Radwaste management was established by the Slovene government in 1991. Our main objective is to provide the final disposal of radioactive waste in Slovenia. Overcoming the NIMBY syndrome is therefore the primary aim of Agency's PR (public relations) strategy. Agency's public relations strategy was prepared in 1993. After very unpleasant experience with NIMBY syndrome in local community where one of the potential locations for low and intermediate level repository was identified the strategy was renewed in 1994. It is divided into two parts: information and education. The first one includes providing information to the media, surveys of press clippings, interviews, press conferences, public opinion polls and publishing articles. Agency's first task in the field of education was to prepare different materials like: leaflets, Agency's newspaper and videos. Materials were distributed to various target publics. There is also a special program of lectures for youngsters. All those activities and projects have been successfully realized within the last year. Plans of PR activities for this year are focused on informing the local community about remediation of temporary storage of radioactive waste near village Zavratec. Other new projects are also under preparation like: new leaflets, presentation on Internet, journalist's guide to rad waste management, most frequently asked questions and answers. (author)

  1. STRATEGI KOMUNIKASI PUBLIC RELATIONS

    Directory of Open Access Journals (Sweden)

    Artis Artis

    2011-11-01

    Full Text Available Living man in interrelates society. Relationship among human being done by gets communication so man one by another one mutually understand and influence regard for the benefit, it that always been practiced by Public Relations( liaison in a governance and also firm institute to reach to the effect which ices. The institute of Public Relations declares for,”Public Relations is overall effort which be passed off by design and berkesenambungan in order to creates and pet keenness and mutual understanding among an organization with whole its member “. In this case, Public Relations in give distribution on manajement's strategy there is two: First, Doing task as part of Public Relations's strategy and involvement in comprehensive process and gives benefit for management an organization. Both of, Public Relations gets role in management strategy in bring off activity to reach to the effect good one gets internal character and also external one correspond to that desirable by good institute on level governance and firm.

  2. Marketing strategy of company

    OpenAIRE

    Václavíková, Petra

    2008-01-01

    Diplomová práce se zabývá problematikou návrhu marketingové strategie pro internetový obchod www.babylonshop.cz. Na základě shromážděných teoretických východisek a analýzy současného stavu firmy byla navržena marketingová strategie, která má zajistit vyšší počet uskutečněných objednávek. V praktické části jsou zhodnoceny analýzy a sestaveny návrhy a doporučení, které by měly zajistit nárůst prodeje a stálých zákazníků. The thesis deals with the proposition of marketing strategy for the Int...

  3. Manajemen Strategi Pengembangan Pariwisata dengan Pendekatan Blue Ocean Strategy

    OpenAIRE

    Muzha, Vianda Kushardianti

    2015-01-01

    Persaingan industri pariwisata di Indonesia saat ini sangatlah ketat, setiap daerah berlomba untuk menonjolkan keunikannya tersendiri. Dengan adanya persaingan yang sangat ketat tersebut, Kota Batu berusaha keluar dari persaingan (red ocean) dengan menciptkan inovasi baru melalui konsep Blue Ocean Strategy. Blue Ocean Strategy adalah istilah dalam ilmu manajemen strategi yang merujuk pada siasat untuk menciptakan pasar baru yang belum dipenuhi persaingan yang ketat. Blue Ocean Strategy pada d...

  4. Strategies for Teaching Astronomy

    Science.gov (United States)

    Bennett, J.

    2000-12-01

    No matter whether you are teaching school children, undergraduates, or colleagues, a few key strategies are always useful. I will present and give examples for the following five key strategies for teaching astronomy. 1. Provide a Contextual Framework: It is much easier to learn new facts or concepts if they can be ``binned" into some kind of pre-existing mental framework. Unless your listeners are already familiar with the basic ideas of modern astronomy (such as the hierarchy of structure in the universe, the scale of the universe, and the origin of the universe), you must provide this before going into the details of how we've developed this modern picture through history. 2. Create Conditions for Conceptual Change: Many people hold misconceptions about astronomical ideas. Therefore we cannot teach them the correct ideas unless we first help them unlearn their prior misconceptions. 3. Make the Material Relevant: It's human nature to be more interested in subjects that seem relevant to our lives. Therefore we must always show students the many connections between astronomy and their personal concerns, such as emphasizing how we are ``star stuff" (in the words of Carl Sagan), how studying other planets helps us understand our own, and so on. 4. Limit Use of Jargon: The number of new terms in many introductory astronomy books is larger than the number of words taught in many first courses in foreign language. This means the books are essentially teaching astronomy in a foreign language, which is a clear recipe for failure. We must find ways to replace jargon with plain language. 5. Challenge Your Students: Don't dumb your teaching down; by and large, students will rise to meet your expectations, as long as you follow the other strategies and practice good teaching.

  5. Military Strategy Of India

    Directory of Open Access Journals (Sweden)

    M. S. Zaitsev

    2017-01-01

    Full Text Available The article analyzes the evolution of military strategy of the Republic of India and key factors that influences its development. New Delhi keeps an eye on the balance of power in South Asia to create favorable conditions for its economic and social development, yet the remaining threats and new challenges still undermine the security and stability in India. The ambitions of China aspiring to power in Asia-Pacific region, combined with its immense military build-up and territorial disputes, cause disturbance in New Delhi. The remaining tensions between India and Pakistan also cause often border skirmishes and medium-scale conflicts. Close relations between China and Pakistan, labeled as “all-weather friendship”, are a source of major concern for India. The fact that both Beijing and Islamabad wield nuclear weapons means that without effective mechanisms of nuclear deterrence any military conflict may turn into a full-scale nuclear war. Terrorist activities and insurgency in the Indian state of Jammu and Kashmir and in the North-Eastern regions of the country, along with maritime piracy and illicit drug trafficking contribute to the complicated nature of the challenges to the Indian security. Indian military strategy is considered as a combination of the army doctrine, maritime doctrine and nuclear doctrine. The Indian political and military leadership wants to meet the challenges of changing geopolitical environment and thus continuously adapts its strategy. However, there is still a gap between theory and practice: Indian armed forces lack the capacity to implement the declared goals because of bulky bureaucratic system, outdated military equipment and insufficient level of command and control. The government needs to mobilize political will and administrative resources to upgrade its defense sector to counter its security threats and challenges.

  6. All strategy is local.

    Science.gov (United States)

    Greenwald, Bruce; Kahn, Judd

    2005-09-01

    The aim of strategy is to master a market environment by understanding and anticipating the actions of other economic agents, especially competitors. A firm that has some sort of competitive advantage-privileged access to customers, for instance--will have relatively few competitors to contend with, since potential competitors without an advantage, if they have their wits about them, will stay away. Thus, competitive advantages are actually barriers to entry and vice versa. In markets that are exposed, by contrast, competition is intense. If the incumbents have even brief success in earning greater than normal returns on investments, new entrants will swarm in to grab a share of the profits. Sooner or later, the additional competition will push returns as far down as the firms' costs of capital. For firms operating in such markets, the only choice is to forget about strategy and run the business as efficiently as possible. Barriers to entry are easier to maintain in a competitive arena that is "local", either in the geographic sense or in the sense of being limited to one product or a handful of related ones. The two most powerful competitive advantages-customer captivity and economies of scale-are more achievable and sustainable in circumscribed markets of this kind. Their opposites are the open markets and host of rivals that are features of globalization. Compapies entering such markets risk frittering away the advantages they secured on smaller playing fields.., Ifa company wants to grow but still obtain superior returns, the authors argue, the best strategy is to dominate a series of discrete but preferably contiguous markets and then expand only at their edges. WalMart's diminishing margins over the past 15 years are strong evidence of the danger of proceeding otherwise.

  7. Strategy and the Internet.

    Science.gov (United States)

    Porter, M E

    2001-03-01

    Many of the pioneers of Internet business, both dot-coms and established companies, have competed in ways that violate nearly every precept of good strategy. Rather than focus on profits, they have chased customers indiscriminately through discounting, channel incentives, and advertising. Rather than concentrate on delivering value that earns an attractive price from customers, they have pursued indirect revenues such as advertising and click-through fees. Rather than make trade-offs, they have rushed to offer every conceivable product or service. It did not have to be this way--and it does not have to be in the future. When it comes to reinforcing a distinctive strategy, Michael Porter argues, the Internet provides a better technological platform than previous generations of IT. Gaining competitive advantage does not require a radically new approach to business; it requires building on the proven principles of effective strategy. Porter argues that, contrary to recent thought, the Internet is not disruptive to most existing industries and established companies. It rarely nullifies important sources of competitive advantage in an industry; it often makes them even more valuable. And as all companies embrace Internet technology, the Internet itself will be neutralized as a source of advantage. Robust competitive advantages will arise instead from traditional strengths such as unique products, proprietary content, and distinctive physical activities. Internet technology may be able to fortify those advantages, but it is unlikely to supplant them. Porter debunks such Internet myths as first-mover advantage, the power of virtual companies, and the multiplying rewards of network effects. He disentangles the distorted signals from the marketplace, explains why the Internet complements rather than cannibalizes existing ways of doing business, and outlines strategic imperatives for dot-coms and traditional companies.

  8. Optimal GENCO bidding strategy

    Science.gov (United States)

    Gao, Feng

    Electricity industries worldwide are undergoing a period of profound upheaval. The conventional vertically integrated mechanism is being replaced by a competitive market environment. Generation companies have incentives to apply novel technologies to lower production costs, for example: Combined Cycle units. Economic dispatch with Combined Cycle units becomes a non-convex optimization problem, which is difficult if not impossible to solve by conventional methods. Several techniques are proposed here: Mixed Integer Linear Programming, a hybrid method, as well as Evolutionary Algorithms. Evolutionary Algorithms share a common mechanism, stochastic searching per generation. The stochastic property makes evolutionary algorithms robust and adaptive enough to solve a non-convex optimization problem. This research implements GA, EP, and PS algorithms for economic dispatch with Combined Cycle units, and makes a comparison with classical Mixed Integer Linear Programming. The electricity market equilibrium model not only helps Independent System Operator/Regulator analyze market performance and market power, but also provides Market Participants the ability to build optimal bidding strategies based on Microeconomics analysis. Supply Function Equilibrium (SFE) is attractive compared to traditional models. This research identifies a proper SFE model, which can be applied to a multiple period situation. The equilibrium condition using discrete time optimal control is then developed for fuel resource constraints. Finally, the research discusses the issues of multiple equilibria and mixed strategies, which are caused by the transmission network. Additionally, an advantage of the proposed model for merchant transmission planning is discussed. A market simulator is a valuable training and evaluation tool to assist sellers, buyers, and regulators to understand market performance and make better decisions. A traditional optimization model may not be enough to consider the distributed

  9. Optimal coal import strategy

    International Nuclear Information System (INIS)

    Chen, C.Y.; Shih, L.H.

    1992-01-01

    Recently, the main power company in Taiwan has shifted the primary energy resource from oil to coal and tried to diversify the coal supply from various sources. The company wants to have the imported coal meet the environmental standards and operation requirements as well as to have high heating value. In order to achieve these objectives, establishment of a coal blending system for Taiwan is necessary. A mathematical model using mixed integer programming technique is used to model the import strategy and the blending system. 6 refs., 1 tab

  10. Analysis of maintenance strategies

    International Nuclear Information System (INIS)

    Laakso, K.; Simola, K.

    1998-01-01

    The main topics of the presentation include: (1) an analysis model and methods to evaluate maintenance action programs and the support decision to make changes in them and (2) to understand the maintenance strategies in a systems perspective as a basis for future developments. The subproject showed how systematic models for maintenance analysis and decision support, utilising computerised and statistical tool packages, can be taken into use for evaluation and optimisation of maintenance of active systems from the safety and economic point of view

  11. Projektlederen ogvirksomhedens strategi

    DEFF Research Database (Denmark)

    Mikkelsen, Hans; Riis, Jens Ove

    2008-01-01

    Ledere af udviklingsprojekter må i stigende grad bruge tid og kræfter på udadvendt ledelse. For udviklingsprojekter skal gennemføres i komplekse og dynamiske omgivelser, hvor formulerede strategier og handlingsplaner ikke entydigt definerer mål og rammer for udviklingsprojekter. Projekterne under...... bevågenhed, mange, mindre forbedringstiltag i dagligdagen udført af Kaizen-grupper og kvalitetsscirkler - og en midtergruppe af enkeltstående udviklingsprojekter, som er afdelingsskabte og konkurrerer om ressourcer og opmærksomhed. Udgivelsesdato: Februar...

  12. Natural hazards science strategy

    Science.gov (United States)

    Holmes, Robert R.; Jones, Lucile M.; Eidenshink, Jeffery C.; Godt, Jonathan W.; Kirby, Stephen H.; Love, Jeffrey J.; Neal, Christina A.; Plant, Nathaniel G.; Plunkett, Michael L.; Weaver, Craig S.; Wein, Anne; Perry, Suzanne C.

    2012-01-01

    The mission of the U.S. Geological Survey (USGS) in natural hazards is to develop and apply hazard science to help protect the safety, security, and economic well-being of the Nation. The costs and consequences of natural hazards can be enormous, and each year more people and infrastructure are at risk. USGS scientific research—founded on detailed observations and improved understanding of the responsible physical processes—can help to understand and reduce natural hazard risks and to make and effectively communicate reliable statements about hazard characteristics, such as frequency, magnitude, extent, onset, consequences, and where possible, the time of future events.To accomplish its broad hazard mission, the USGS maintains an expert workforce of scientists and technicians in the earth sciences, hydrology, biology, geography, social and behavioral sciences, and other fields, and engages cooperatively with numerous agencies, research institutions, and organizations in the public and private sectors, across the Nation and around the world. The scientific expertise required to accomplish the USGS mission in natural hazards includes a wide range of disciplines that this report refers to, in aggregate, as hazard science.In October 2010, the Natural Hazards Science Strategy Planning Team (H–SSPT) was charged with developing a long-term (10-year) Science Strategy for the USGS mission in natural hazards. This report fulfills that charge, with a document hereinafter referred to as the Strategy, to provide scientific observations, analyses, and research that are critical for the Nation to become more resilient to natural hazards. Science provides the information that decisionmakers need to determine whether risk management activities are worthwhile. Moreover, as the agency with the perspective of geologic time, the USGS is uniquely positioned to extend the collective experience of society to prepare for events outside current memory. The USGS has critical statutory

  13. Conceptualizing operations strategy processes

    DEFF Research Database (Denmark)

    Rytter, Niels Gorm; Boer, Harry; Koch, Christian

    2007-01-01

    Purpose - The purpose of this paper is to present insights into operations strategy (OS) in practice. It outlines a conceptualization and model of OS processes and, based on findings from an in-depth and longitudinal case study, contributes to further development of extant OS models and methods......; taking place in five dimensions of change - technical-rational, cultural, political, project management, and facilitation; and typically unfolding as a sequential and parallel, ordered and disordered, planned and emergent as well as top-down and bottom-up process. The proposed OS conceptualization...

  14. Optimal intermittent search strategies

    Energy Technology Data Exchange (ETDEWEB)

    Rojo, F; Budde, C E [FaMAF, Universidad Nacional de Cordoba, Ciudad Universitaria, X5000HUA Cordoba (Argentina); Wio, H S [Instituto de Fisica de Cantabria, Universidad de Cantabria and CSIC E-39005 Santander (Spain)

    2009-03-27

    We study the search kinetics of a single fixed target by a set of searchers performing an intermittent random walk, jumping between different internal states. Exploiting concepts of multi-state and continuous-time random walks we have calculated the survival probability of a target up to time t, and have 'optimized' (minimized) it with regard to the transition probability among internal states. Our model shows that intermittent strategies always improve target detection, even for simple diffusion states of motion.

  15. Town Centre Redevelopment Strategies

    DEFF Research Database (Denmark)

    Vagnby, Bo Hellisen

    After many years of urban growth Danish downtowns are facing some important choices. Shall the stake one-sidedly be on the town centres as driving forces for growth and 'city marketing', or do they still have a role to play in a broader socio-economic context? In the paper we look back on eight...... as slum clearence and urban renewal. To a certain extent parallels are drawn to international experiences, especially where these are of such a nature that they can be assumed transferred to Danish connctions. Conclusively, the strategies are discussed in the light of the turn of Danish urban planning...

  16. Pricing strategies for information goods

    Indian Academy of Sciences (India)

    Pricing strategies; information goods; bundling and versioning strategies; ... variety of industries including books, music, entertainment, gaming and education. ... Decision and Information Technologies Department, Robert H Smith School of ...

  17. National Strategies for Technological Innovation

    Science.gov (United States)

    Rossini, Frederick; Bozeman, Barry

    1977-01-01

    Considers the implications of the technological innovation literature for possible national strategies for innovation. Sketches highly generalized innovation strategies for nations at various levels of technological development. (Author/IRT)

  18. Strategies for Sustainable Energy Development

    DEFF Research Database (Denmark)

    Meyer, Niels I

    2009-01-01

    The paper analyses international strategies for establishing a sustainable energy development. Proposals are given for mitigation of global warming.......The paper analyses international strategies for establishing a sustainable energy development. Proposals are given for mitigation of global warming....

  19. INL Vision and Strategy 2015

    International Nuclear Information System (INIS)

    Pillai, Rekha Sukamar

    2015-01-01

    This Laboratory vision and strategy presents INL's vision and strategy for the Laboratory and is our introduction to a special place dedicated to improving our nation's energy security future.

  20. China's Maritime Strategy Peaceful Rise

    National Research Council Canada - National Science Library

    Horrell, Steven L

    2008-01-01

    .... As a result the global maritime environment will be key to this continental power's continued growth As a subset of maritime strategy China's naval strategy and accompanying People's Liberation Army...

  1. National Strategy to Secure Cyberspace

    National Research Council Canada - National Science Library

    Schwalm, Keith T

    2006-01-01

    ... of a national strategy for securing cyberspace. The approach explored the development of cyber technology strategies and programs related to the mission and roles of Homeland Security Advanced Research Projects Agency...

  2. Market strategies for climate change

    NARCIS (Netherlands)

    Kolk, A.; Pinkse, J.M.

    2004-01-01

    The issue of climate change has attracted increasing business attention in the past decade. Whereas companies initially aimed primarily at influencing the policy debate, corporate strategies increasingly include economic responses. Existing classifications for climate change strategies however still

  3. Inspection Strategies for Concrete Bridges

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Thoft-Christensen, Palle

    1989-01-01

    In this paper an optimal inspection strategy for concrete bridges based on periodic routine and detailed inspections is presented. The failure mode considered is corrosion of the reinforcement due to chlorides. A simple modelling of the corrosion and of the inspection strategy is presented....... The optimal inspection strategy is determined from an optimization problem, where the design variables are time intervals between detailed inspections and the concrete cover. The strategy is illustrated on a simple structure, namely a reinforced concrete beam....

  4. Non-oblivious Strategy Improvement

    OpenAIRE

    Fearnley, John

    2010-01-01

    We study strategy improvement algorithms for mean-payoff and parity games. We describe a structural property of these games, and we show that these structures can affect the behaviour of strategy improvement. We show how awareness of these structures can be used to accelerate strategy improvement algorithms. We call our algorithms non-oblivious because they remember properties of the game that they have discovered in previous iterations. We show that non-oblivious strategy improvement algorit...

  5. A responsible remediation strategy

    International Nuclear Information System (INIS)

    Knowles, C.R.

    1992-01-01

    This paper deals with an approach to cleaning up the residue of 150 years of intense urban and industrial development in the United States. The discussion focuses on several choices and strategies that business can adopt given the existing environmental laws and the socio-economic trends of the 1990's. The thesis of this paper is that the best business strategy for dealing with environmental liabilities is to act affirmatively and aggressively. An aggressive, pro-active approach to environmental remediation liabilities makes good business sense. It allows a company to learn the true size of the problem early. Early assessment and prioritization allows one to control the course and conduct of the cleanup. Early voluntary action is always viewed favorably by agencies. It gives one control over spending patterns which has value in and of itself. Voluntary cleanups are certainly faster and invariably more efficient. And they attain clearly acceptable standards. The volunteering company that takes the lead in a multi-party site finds that the courts are supportive in helping the volunteer collect from recalcitrant polluters. All of these pluses have a direct and positive impact on the bottom line and that means that the aggressive approach is the right thing to do for both stockholders and the communities where a business exists

  6. Patent protection strategies

    Directory of Open Access Journals (Sweden)

    Himanshu Gupta

    2010-01-01

    Full Text Available It is widely recognized that the pharmaceutical industry faces serious financial challenges. Large numbers of blockbuster drugs are losing patent protection and going generic. The pipeline of new drugs is too sparse to fill the gap and generate a platform for future growth. Moreover, many of the new products are biologics with much narrower target patient populations and comparatively higher prices relative to traditional pharmaceuticals. So now the time has come for pharmaceutical scientists to have a better understanding of patent fundamentals. This need is illustrated by analyses of key scientific and legal issues that arose during recent patent infringement cases involving Prozac, Prilosec, and Buspar. Facing this scenario, the pharmaceutical industry has moved to accelerate drug development process and to adopt at the same time different strategies to extend the life time of the patent monopoly to provide the economic incentives and utilizing it for drug discovery and development. This review covers the need of patent protection and various strategies to extend the patent.

  7. Strategies for stroke rehabilitation.

    Science.gov (United States)

    Dobkin, Bruce H

    2004-09-01

    Rehabilitation after hemiplegic stroke has typically relied on the training of patients in compensatory strategies. The translation of neuroscientific research into care has led to new approaches and renewed promise for better outcomes. Improved motor control can progress with task-specific training incorporating increased use of proximal and distal movements during intensive practice of real-world activities. Functional gains are incorrectly said to plateau by 3-6 months. Many patients retain latent sensorimotor function that can be realised any time after stroke with a pulse of goal-directed therapy. The amount of practice probably best determines gains for a given level of residual movement ability. Clinicians should encourage patients to build greater strength, speed, endurance, and precision of multijoint movements on tasks that increase independence and enrich daily activity. Imaging tools may help clinicians determine the capacity of residual networks to respond to a therapeutic approach and help establish optimal dose-response curves for training. Promising adjunct approaches include practice with robotic devices or in a virtual environment, electrical stimulation to increase cortical excitability during training, and drugs to optimise molecular mechanisms for learning. Biological strategies for neural repair may augment rehabilitation in the next decade.

  8. CMS multicore scheduling strategy

    International Nuclear Information System (INIS)

    Yzquierdo, Antonio Pérez-Calero; Hernández, Jose; Holzman, Burt; Majewski, Krista; McCrea, Alison

    2014-01-01

    In the next years, processor architectures based on much larger numbers of cores will be most likely the model to continue 'Moore's Law' style throughput gains. This not only results in many more jobs in parallel running the LHC Run 1 era monolithic applications, but also the memory requirements of these processes push the workernode architectures to the limit. One solution is parallelizing the application itself, through forking and memory sharing or through threaded frameworks. CMS is following all of these approaches and has a comprehensive strategy to schedule multicore jobs on the GRID based on the glideinWMS submission infrastructure. The main component of the scheduling strategy, a pilot-based model with dynamic partitioning of resources that allows the transition to multicore or whole-node scheduling without disallowing the use of single-core jobs, is described. This contribution also presents the experiences made with the proposed multicore scheduling schema and gives an outlook of further developments working towards the restart of the LHC in 2015.

  9. Anorexia: A "losing" strategy?

    Science.gov (United States)

    Mealey, L

    2000-03-01

    Several theorists have tried to model anorexia on Wasser and Barash's (1983) "reproductive suppression model" (RSM). According to the RSM, individual females adaptively suppress their reproductive functioning under conditions of social or physiological stress. From this perspective, mild anorexia is viewed as an adaptive response to modern conditions; more severe anorexia is viewed as an adaptation gone awry. Previous models have not, however, examined the full richness of the RSM. Specifically, Wasser and Barash documented not only self-imposed reproductive suppression, but also manipulative reproductive suppression of subordinate females by dominants. I propose that the modern "epidemic" of anorexia is explained neither by adaptive self-suppression nor by environmental mismatch (an adaptation gone awry); I propose that the "epidemic" levels of anorexia seen in modern western society are a direct consequence of intrasexual competition, the scope of which has been enhanced by the power and reach of modern communications media. According to this perspective, anorexia, even in its mild forms, is a manipulative strategy imposed on subordinates by dominants. Anorexia is, in both senses, a "losing" strategy.

  10. Strategies in the HSCM

    Directory of Open Access Journals (Sweden)

    Hung-Chang Liao

    2015-01-01

    Full Text Available The purpose of this study was to establish a hospital supply chain management (HSCM model in which three kinds of drugs in the same class and with the same indications were used in creating an optimal robust design and adjustable ordering strategies to deal with a drug shortage. The main assumption was that although each doctor has his/her own prescription pattern, when there is a shortage of a particular drug, the doctor may choose a similar drug with the same indications as a replacement. Four steps were used to construct and analyze the HSCM model. The computation technology used included a simulation, a neural network (NN, and a genetic algorithm (GA. The mathematical methods of the simulation and the NN were used to construct a relationship between the factor levels and performance, while the GA was used to obtain the optimal combination of factor levels from the NN. A sensitivity analysis was also used to assess the change in the optimal factor levels. Adjustable ordering strategies were also developed to prevent drug shortages.

  11. Ruslands strategi i Arktis

    DEFF Research Database (Denmark)

    Staun, Jørgen Meedom

    Russia’s strategy in the Arctic is dominated by two overriding discourses – and foreign policy directions – which at first glance may look like opposites. On the one hand, an IR realism/geopolitical discourse that often has a clear patriotic character, dealing with “capturing”, “winning” or “conq......Russia’s strategy in the Arctic is dominated by two overriding discourses – and foreign policy directions – which at first glance may look like opposites. On the one hand, an IR realism/geopolitical discourse that often has a clear patriotic character, dealing with “capturing”, “winning......-focused discourse, which is characterized by words such as “negotiation”, “cooperation” and “joint ventures” and which has as an axiom that the companies and countries operating in the Arctic all benefit the most if they collaborate in peace and friendliness. So far, the IR liberalism discourse has set the trend...... into the projects is uncertain. The hard-pressed Russian economy, with the prospects of recession, increasing inflation, increasing flight of capital, rising interest rates and a continuously low oil price, provides a market economic incentive for suspending the projects until further notice. Whether the Kremlin...

  12. Public information strategies

    International Nuclear Information System (INIS)

    Waldahl, R.

    1995-01-01

    The Chernobyl accident in 1986 uncovered serious information problems in many Western countries, and started a debate on crisis communication and information strategies in relation to radiation danger in society. The information problem focuses on four main perspectives. The first is related to information as a persuasion process in which an efficient strategy would influence both the public's knowledge of radiation danger, their attitude towards it and their behaviour. The second perspective calls attention to the importance of the different elements of the information process. How important are different characteristics of the information source; the message itself, and the receiver? The third perspective concentrates on different types of information. What is this issue all about, why is the situation as it is, and how should people behave to protect themselves? The fourth perspective points to the various phases of a crisis. The information needed is obviously not the same in the period before a crisis emerges when no one knows what is going to happen, in the warning period when one knows that something may happen, and during the crisis itself. (Author)

  13. The HGF strategy project

    International Nuclear Information System (INIS)

    Knebel, J.U.; Fellmoser, F.; Lefhalm, C.; Mack, K.; Pettan, C.; Piecha, H.; Konys, J.; Adelhelm, C.; Glasbrenner, H.; Muscher, H.; Novotny, J.; Voss, Z.; Wedemeyer, O.; Mueller, G.; Heinzel, A.; Schumacher, G.; Huber, R.; Zimmermann, F.; Groetzbach, G.; Dorr, B.; Carteciano, L.N.

    2000-01-01

    Within the Hermann von Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF) an HGF-Strategy Fund Project entitled 'Innovative Technologies to Reduce Radiotoxicity' is funded since October 1999. The objectives of this HGF-Strategy Fund Project is the development of new methods and technologies to design and manufacture thin-walled and highly thermally-loaded surfaces which are cooled by a corrosive heavy liquid metal (lead-bismuth eutectic). The result of this project will be the basic scientific-technical tool which allows the conception and the design of a European Demonstrator of an ADS system (cf. 32.23.05). The work performed at Forschungszentrum Karlsruhe is embedded in a broad European research and development programme on ADS systems. The project is divided in three sub-projects: Sub-Project 1: Thermalhydraulic Investigations, Sub-Project 2: Material Specific Investigations, Sub-Project 3: Oxygen Control System. This progress report gives a general description of the project and its envisaged objectives. As a selection of the results achieved, first, FLUTAN calculations for the COULI beam window design and, second, the oxygen control system for the KArlsruhe Lead LAboratory KALLA are described in detail. Finally, the design and status of KALLA is given. (orig.)

  14. A strategy model for management

    DEFF Research Database (Denmark)

    Friis, Ole Uhrskov; Holmgren, Jens; Eskildsen, Jacob Kjær

    2016-01-01

    Purpose: Developing a strategy model which explains what organisations should focus on in their strategy work, both in terms of the environment as well as how the strategy is implemented. In addition, the purpose is to demonstrate how this can influence and improve the organisations’ performance....

  15. Operations Strategy with Paper Boats

    Science.gov (United States)

    Sumukadas, Narendar

    2010-01-01

    When participants in introductory business courses encounter the term "operations strategy," it is not easy for them to appreciate what operations strategy is about, or how it fits with overall business strategy. This game breaks down highfalutin jargon into experiences that participants can readily relate to. While working in teams to make paper…

  16. Strategy development marketing commercial enterprise

    OpenAIRE

    Shatalov D. S.; Hamidova O. M.

    2016-01-01

    in the scientific article the necessity of development and implementation of marketing strategies in the activity of any commercial enterprise, we give a meaningful description of the concept of «marketing strategy» and develop requirements for the selection strategy of trade enterprise.

  17. Decision Strategy Research

    Energy Technology Data Exchange (ETDEWEB)

    Hardeman, F

    2001-04-01

    The objective of SCK-CEN's R and D programme on decision strategies is: (1) to study the decision-making process in a nuclear context with particular emphasis on emergency preparedness; (2) to disseminate knowledge on nuclear emergency preparedness including courses in the field of off-site emergency response to nuclear accidents; (3) to co-ordinate efforts within SCK-CEN in the field of medical applications of radiation; (4) to support projects and reflexion groups related to interdisciplinary research on the no-technical aspects of radiation protection or nuclear apllications; (5) to give advice and support to authorities and the industry on any topic related to radiation protection and to make expertise and infrastructure available. Main focus of the programme is on the surveillance of the territory and emergency preparedness. Principal achievements in 2000 are described.

  18. SPORT MARKETING MIX STRATEGIES

    Directory of Open Access Journals (Sweden)

    Alexandru Lucian MIHAI

    2013-06-01

    Full Text Available This paper presents a brief overview of a significant element of the sport marketing management model called the marketing mix. The marketing mix is crucial because it defines the sport business, and much of the sport marketer’s time is spent on various functions within the marketing mix. The marketing mix is the strategic combination of the product, price, place and promotion elements. These elements are typically called the four Ps of marketing. Decisions and strategies for each are important for the marketer. Information for making educated decisions involving the four Ps comes from the marketing research involving primarily the four Cs - consumer, competitor, company and climate. A critical decision and one of the greatest challenges for the sport business is how to strategically combine the four Ps to best satisfy the consumer, meet company objectives, enhance market position, and enhance competitive advantages.

  19. SAGD operating strategies

    Energy Technology Data Exchange (ETDEWEB)

    Nasr, T. N.; Golbeck, H.; Korpany, G.; Pierce, G. [Alberta Research Council, Edmonton, AB (Canada)

    1998-12-31

    Steam-assisted gravity drainage (SAGD) has become one of the most effective means of recovering oil from oil sands deposits that are too deeply buried for surface mining. In general terms, the process involves drilling paired horizontal wells, one well above the other, and separated by a distance, near the bottom of the oil-bearing formation. The top well is used to inject the steam, heating up the oil and allowing it to drain under the action of gravity, into the bottom well. This paper reviews advances in SAGD operating strategies, based on work at the Underground Test Facility (UTF) in Alberta. Problems that continue to challenge researchers and operators, and concepts to overcome these challenges are discussed in terms of laboratory studies at UTF, designed to improve SAGD oil-to-steam ratios and to reduce water requirements for the process. 8 refs., 20 figs.

  20. Product Architecture Modularity Strategies

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan

    2003-01-01

    The focus of this paper is to integrate various perspectives on product architecture modularity into a general framework, and also to propose a way to measure the degree of modularization embedded in product architectures. Various trade-offs between modular and integral product architectures...... and how components and interfaces influence the degree of modularization are considered. In order to gain a better understanding of product architecture modularity as a strategy, a theoretical framework and propositions are drawn from various academic literature sources. Based on the literature review......, the following key elements of product architecture are identified: components (standard and new-to-the-firm), interfaces (standardization and specification), degree of coupling, and substitutability. A mathematical function, termed modularization function, is introduced to measure the degree of modularization...

  1. LHCb software strategy

    CERN Document Server

    Van Herwijnen, Eric

    1998-01-01

    This document describes the software strategy of the LHCb experiment. The main objective is to reuse designs and code wherever possible; We will implement an architecturally driven design process; This architectural process will be implemented using Object Technology; We aim for platform indepence; try to take advantage of distributed computing and will use industry standards, commercial software and profit from HEP developments; We will implement a common software process and development environment. One of the major problems that we are immediately faced with is the conversion of our current code from Fortran into an Object Oriented language and the conversion of our current developers to Object technology. Some technical terms related to OO programming are defined in Annex A.1

  2. Nuclear reactor strategies

    International Nuclear Information System (INIS)

    Konno, H.; Srinivasan, T.N.

    1975-01-01

    Reference is made to a linear programming model considered by Hafele and Manne ('Strategies for a Transition from Fossil to Nuclear Fuels'. 11ASA Research Report RR-74-7) in which the sum of discounted costs of meeting demand for electrical and non-electrical energy over a horizon of 75 years divided into 25 periods of 3 years is minimised subject to constraints, inter alia, on the total availability of fossil fuel and low cost ($15/lb) natural uranium. The sensitivity of the Hafele-Manne results are explored with respect to changes in some crucial parameters and assumptions namely; variation in discount rate, variation in current costs of operation of HTRB, variation in costs and availability of natural uranium, market penetration constraints, changing capital costs, price responsive demands, petroleum prices, and minimisation of PETG consumption with constraints on the sum of discounted costs. (U.K.)

  3. Business strategies for climate

    International Nuclear Information System (INIS)

    Duchene, Patrice-Henry; Colas, Julien; Boulharouf, Zoubeida; Chalendar, Pierre-Andre de; Baecher, Cedric; Fonta, Philippe; Gay, Guillaume; Timbaud, Xavier; Rivallain, Mathieu; Salomon, Thierry

    2015-03-01

    Studies published in 2014, whether by IPCC scientists or New Climate Economy economists, showed that it is still possible to combat climate change without having to give up on economic growth and human development. This applies both to emerging countries which do not want to give up on their promised growth and to developed countries that fear having to surrender their lifestyles. Positioning ourselves on a greenhouse gas emission trajectory enabling us to limit global warming to 2 deg. C by the end of this century nonetheless requires a far-reaching and immediate response coordinated by all economic and political stakeholders. Companies know that they have a major role to play in dealing with the climate challenge. They are ready to change direction, as the United Nations Secretary-General Ban Kimoon urged them to do in September 2014. Companies of all sizes engaged in this process innovate and develop technological, organisational and financial solutions to reduce greenhouse gas emissions and adapt to the consequences of climate change. They are adjusting their strategies and economic models in response to these new challenges. It is these solutions that are presented in this publication 'Business strategies for climate'. All sectors of the economy are concerned; companies in all sectors can take a forward-looking approach to the changes caused by climate change and mobilise their resources to provide effective responses in line with the issues at stake. Global economic growth is resulting in a huge increase in the demand for mobility and transport. Companies are working on ways to improve vehicles, develop engines that are less fossil-fuel dependent, and on finding new ways for people to move around and to transport goods. The challenge is considerable: it will involve working with the growing need for transport while at the same time massively reducing the sector's greenhouse gas emissions. Cities are home to an ever-increasing number of people

  4. Inventory control strategies

    International Nuclear Information System (INIS)

    Primrose, D.

    1998-01-01

    Finning International Inc. is in the business of selling, financing and servicing Caterpillar and complementary equipment. Its main markets are in western Canada, Britain and Chile. This paper discusses the parts inventory strategies system for Finning (Canada). The company's territory covers British Columbia, Alberta, the Yukon and the Northwest Territories. Finning's parts inventory consists of 80,000 component units valued at more than $150 M. Distribution centres are located in Langley, British Columbia and Edmonton, Alberta. To make inventory and orders easier to control, Finning has designed a computer-based system, with software written exclusively for Caterpillar dealers. The system makes use of a real time electronic interface with all Finning locations, plus all Caterpillar facilities and other dealers in North America. Details of the system are discussed, including territorial stocking procedures, addition to stock, exhaustion of stock, automatic/suggest order controls, surplus inventory management, and procedures for jointly managed inventory. 3 tabs., 1 fig

  5. Decision Strategy Research

    International Nuclear Information System (INIS)

    Hardeman, F.

    2001-01-01

    The objective of SCK-CEN's R and D programme on decision strategies is: (1) to study the decision-making process in a nuclear context with particular emphasis on emergency preparedness; (2) to disseminate knowledge on nuclear emergency preparedness including courses in the field of off-site emergency response to nuclear accidents; (3) to co-ordinate efforts within SCK-CEN in the field of medical applications of radiation; (4) to support projects and reflexion groups related to interdisciplinary research on the no-technical aspects of radiation protection or nuclear apllications; (5) to give advice and support to authorities and the industry on any topic related to radiation protection and to make expertise and infrastructure available. Main focus of the programme is on the surveillance of the territory and emergency preparedness. Principal achievements in 2000 are described

  6. Designing concepts and strategies

    DEFF Research Database (Denmark)

    Kiib, Hans

    2012-01-01

    , that new developments often employ very modest research on the subject and often very little has been done in order to challenge traditional concepts and to invent new sustainable concepts for redevelopment. In order to avoid mistakes in urban redevelopment we need to learn from research and evaluation...... of the best planning practice. But what might be just as important is to learn from concept development practice, which can give us a comprehensive understanding of our complex cities and make us develop a way of experiencing the unique qualities of the architectural typologies at the site. Finally...... and strategies are briefly described in the article, and the adaption by city planners and developers has been critical reviewed....

  7. SURF Model Calibration Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Menikoff, Ralph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-10

    SURF and SURFplus are high explosive reactive burn models for shock initiation and propagation of detonation waves. They are engineering models motivated by the ignition & growth concept of high spots and for SURFplus a second slow reaction for the energy release from carbon clustering. A key feature of the SURF model is that there is a partial decoupling between model parameters and detonation properties. This enables reduced sets of independent parameters to be calibrated sequentially for the initiation and propagation regimes. Here we focus on a methodology for tting the initiation parameters to Pop plot data based on 1-D simulations to compute a numerical Pop plot. In addition, the strategy for tting the remaining parameters for the propagation regime and failure diameter is discussed.

  8. Hospital turnaround strategies.

    Science.gov (United States)

    Langabeer, James

    2008-01-01

    Despite reports of higher profitability in recent years, hospitals are failing at a faster rate than ever before. Although many hospitals leave decisions regarding revenues and costs to chief financial officers and their staff, this is a recipe for disaster. From research conducted over the last 4 years on hospital bankruptcies and turnarounds, the author found that a common series of actions will help organizations evade collapse. The author explored these turnaround strategies through research and analysis of a variety of hospitals and health systems that had a high probability of immediate financial crisis or collapse. His continued observation and analysis of these hospitals in subsequent years showed that most hospitals never emerge from their bleak financial conditions. However, a few hospital administrations have successfully turned around their organizations.

  9. Tax Strategy Control

    DEFF Research Database (Denmark)

    Rossing, Christian Plesner

    2013-01-01

    This paper examines how a functional tax strategy impacts the management control system (MCS) in a multinational enterprise (MNE) facing transfer pricing tax risks. Based on case study findings it is argued that the MCS in a multinational setting is contingent upon the MNE's response to its tax...... environment. Moreover, the paper extends existing contingency-based theory on MCS by illustrating the role of inter-organisational network collaboration across MNE transfer pricing tax experts. This collaboration, caused by a widely dispersed tax knowledge base, fuels the formal interactive control system...... and reduces tax uncertainty. The paper adopts an interdisciplinary approach for explaining findings, using contingency-based theory and network theory at the inter-organisational level....

  10. Optimal fuel inventory strategies

    International Nuclear Information System (INIS)

    Caspary, P.J.; Hollibaugh, J.B.; Licklider, P.L.; Patel, K.P.

    1990-01-01

    In an effort to maintain their competitive edge, most utilities are reevaluating many of their conventional practices and policies in an effort to further minimize customer revenue requirements without sacrificing system reliability. Over the past several years, Illinois Power has been rethinking its traditional fuel inventory strategies, recognizing that coal supplies are competitive and plentiful and that carrying charges on inventory are expensive. To help the Company achieve one of its strategic corporate goals, an optimal fuel inventory study was performed for its five major coal-fired generating stations. The purpose of this paper is to briefly describe Illinois Power's system and past practices concerning coal inventories, highlight the analytical process behind the optimal fuel inventory study, and discuss some of the recent experiences affecting coal deliveries and economic dispatch

  11. Divestiture: strategy's missing link.

    Science.gov (United States)

    Dranikoff, Lee; Koller, Tim; Schneider, Antoon

    2002-05-01

    Although most companies dedicate considerable time and attention to acquiring and creating businesses, few devote much effort to divestitures. But regularly divesting businesses--even good, healthy ones--ensures that remaining units reach their potential and that the overall company grows stronger. Drawing on extensive research into corporate performance over the last decade, McKinsey consultants Lee Dranikoff, Tim Koller, and Antoon Schneider show that an active divestiture strategy is essential to a corporation's long-term health and profitability. In particular, they say that companies that actively manage their businesses through acquisitions and divestitures create substantially more shareholder value than those that passively hold on to their businesses. Therefore, companies should avoid making divestitures only in response to pressure and instead make them part of a well-thought-out strategy. This article presents a five-step process for doing just that: prepare the organization, identify the best candidates for divestiture, execute the best deal, communicate the decision, and create new businesses. As the fifth step suggests, divestiture is not an end in itself. Rather, it is a means to a larger end: building a company that can grow and prosper over the long haul. Wise executives divest so that they can create new businesses and expand existing ones. All of the funds, management time, and support-function capacity that a divestiture frees up should therefore be reinvested in creating shareholder value. In some cases, this will mean returning money to shareholders. But more likely than not, it will mean investing in attractive growth opportunities. In companies as in the marketplace, creation and destruction go hand in hand; neither flourishes without the other.

  12. Diversity as strategy.

    Science.gov (United States)

    Thomas, David A

    2004-09-01

    IBM's turnaround in the last decade is an impressive and well-documented business story. But behind that success is a less told people story, which explains how the corporation dramatically altered its already diverse composition and created millions of dollars in new business. By the time Lou Gerstner took the helm in 1993, IBM had a long history of progressive management when it came to civil rights and equal-opportunity employment. But Gerstner felt IBM wasn't taking full advantage of a diverse market for talent, nor was it maximizing the potential of its diverse customer and employee base. So in 1995, he launched a diversity task force initiative to uncover and understand differences among people within the organization and find ways to appeal to an even broader set of employees and customers. Gerstner established a task force for each of eight constituencies: Asians; blacks; the gay, lesbian, bisexual, transgendered community; Hispanics; white men; Native Americans; people with disabilities; and women. He asked the task forces to research four questions: What does your constituency need to feel welcome and valued at IBM? What can the corporation do, in partnership with your group, to maximize your constituency's productivity? What can the corporation do to influence your constituency's buying decisions so that IBM is seen as a preferred solution provider? And with which external organizations should IBM form relationships to better understand the needs of your constituency? The answers to these questions became the basis for IBM's diversity strategy. Thomas stresses that four factors are key to implementing any major change initiative: strong support from company leaders, an employee base that is fully engaged with the initiative, management practices that are integrated and aligned with the effort, and a strong and well-articulated business case for action. All four elements have helped IBM make diversity a key corporate strategy tied to real growth.

  13. Newer antiatherosclerosis treatment strategies.

    Science.gov (United States)

    Aggarwal, Amitesh; Singh, Safal

    2011-01-01

    Atherosclerosis has been a target of much clinical and molecular research. As a result of this extensive research, it is amply clear that atherogenesis is a multifactorial process involving an interplay of metabolic, immune and inflammatory mechanisms. Antiatherosclerotic strategies are today aiming for a multipronged approach targeting each arm of this multifactorial process. The newer agents under development can be divided into three broad categories: anti-inflammatory agents, modulators of intermediary metabolism and antiatherosclerosis vaccines. Potential targets for anti-inflammatory agents include inhibition of conversion of low-density lipoprotein (LDL) to oxidised LDL, blocking or downregulation of cell adhesion molecules, chemokine modulation and macrophage receptor blockade. Beyond inhibition of plaque formation, efforts are also ongoing to develop agents which stabilise the plaque by increasing its fibrous content and inhibiting its disruption. So far as research in the sphere of intermediary metabolism is concerned, the focus is now primarily on raising high-density lipoprotein and promoting reverse cholesterol transport; potential targets include cholesteryl ester transfer protein, liver X-receptor, lecithin cholesterol acyltransferase and high-density lipoprotein mimetics. Acyl-coenzymeA: cholesterol acyltransferase is another enzyme whose selective and differential inhibition is under active investigation. The concept of immunisation against a non-communicable disease such as atherosclerosis is still in its nascent stages. However, with increasing evidence to suggest the role of antigen-specific T-cell-mediated immunity in atherogenesis, this approach is potentially promising. Possible antigens under evaluation include oxidised LDL and its subparticles, heat-shock proteins and cholesteryl ester transfer protein. With cardiovascular disease being the single leading cause of death worldwide, the development of a safe and successful antiatherosclerosis

  14. Supervisory Control Strategy Development

    International Nuclear Information System (INIS)

    Gary D Storrick; Bojan Petrovic

    2007-01-01

    Task 4 of this collaborative effort between ORNL, Brazil, and Westinghouse for the International Nuclear Energy Research Initiative entitled 'Development of Advanced Instrumentation and Control for an Integrated Primary System Reactor' focused on the design of the hierarchical supervisory control for multiple-module units. The state of the IRIS plant design--specifically, the lack of a detailed secondary system design--made developing a detailed hierarchical control difficult at this time. However, other simultaneous and ongoing efforts have contributed to providing the needed information. This report summarizes the results achieved under Task 4 of this Financial Assistance Award. Section 1.2 describes the scope of this effort. Section 2 discusses the IRIS control functions. Next, it briefly reviews the current control concepts, and then reviews the maneuvering requirements for the IRIS plant. It closes by noting the benefits that automated sequences have in reducing operator workload. Section 3 examines reactor loading in the frequency domain to establish some guidelines for module operation, paying particular attention to strategies for using process steam for desalination and/or district heating. The final subsection discusses the implications for reactor control, and argues that using the envisioned percentage (up to 10%) of the NSSS thermal output for these purposes should not significantly affect the NSSS control strategies. Section 4 uses some very general economic assumptions to suggest how one should approach multi-module operation. It concludes that the well-known algorithms used for economic dispatching could be used to help manage a multi-unit IRIS site. Section 5 addresses the human performance factors of multi-module operation. Section 6 summarizes our conclusions

  15. WHEN BUSINESS STRATEGY MEETS CREATIVITY

    Directory of Open Access Journals (Sweden)

    Sorin-George TOMA

    2013-12-01

    Full Text Available Purpose – Our paper aims to present in short the theoretical foundation of the concepts of business strategy and creativity, and to highlight the relationship between them. Design/methodology/approach – Using the literature review, the study examined the conceptual framework of the notions of strategy, business strategy, and creativity. Also, it analysed the relationship between business strategy and creativity. Findings – The results confirm previous studies related to the beneficial impact of creativity on the business strategy of a company. As creativity has become an important input for a successful business strategy, companies are making significant efforts in order to bring creativity into play. Practical implications/originality/value – Business strategy and creativity are two interconnected concepts not only in theory, but also in practice. Also, creativity represents a fundamental asset of a successful company in turbulent times.

  16. Employment strategy of the Russians

    Directory of Open Access Journals (Sweden)

    Vladimir Borisovich Toreev

    2015-05-01

    Full Text Available During the crisis it is especially important to choose a correct employment strategy. Every employee uses an employment strategy, as he/she selects the direction of long-term employment consciously or intuitively. The choice of strategy is determined by a number of factors shaping the person’s attitudes: health, character, upbringing, education, social environment, institutional environment. The employment strategies of the young people newly entering the labor market differ from lab our strategies of workers. Young people do not have such experience and can plan their life “from scratch”. The Soviet specialists, people who started their career in the planned economy, have their own features of employment strategies. The article describes employment strategies of the Russians

  17. Probability matching and strategy availability.

    Science.gov (United States)

    Koehler, Derek J; James, Greta

    2010-09-01

    Findings from two experiments indicate that probability matching in sequential choice arises from an asymmetry in strategy availability: The matching strategy comes readily to mind, whereas a superior alternative strategy, maximizing, does not. First, compared with the minority who spontaneously engage in maximizing, the majority of participants endorse maximizing as superior to matching in a direct comparison when both strategies are described. Second, when the maximizing strategy is brought to their attention, more participants subsequently engage in maximizing. Third, matchers are more likely than maximizers to base decisions in other tasks on their initial intuitions, suggesting that they are more inclined to use a choice strategy that comes to mind quickly. These results indicate that a substantial subset of probability matchers are victims of "underthinking" rather than "overthinking": They fail to engage in sufficient deliberation to generate a superior alternative to the matching strategy that comes so readily to mind.

  18. Strategy Innovation with Employee Involvement

    DEFF Research Database (Denmark)

    Friis, Ole Uhrskov; Koch, Christian

    2015-01-01

    The purpose of this article is to investigate how employees can be involved in strategy innovation processes and how new strategy practices (new tools and procedures) are used to change strategy praxis in order to sustain value creation. In the strategizing actions, we found that even...... if the managers still dominate, some processes of direct involvement of employees occur, in particular when employees are asked to supplement overall strategic goals and when they directly shape several sub-strategies. Strategy practices found include strategy planning, an open space workshop and organised...... strategy projects. Especially the latter two are important in facilitating the employee involvement. The case, however, also exhibits enterprise-situated praxises related to unplanned events, like the mitigation of taboos....

  19. Immunosuppressive strategies and management

    Institute of Scientific and Technical Information of China (English)

    Shi-hui PAN

    2008-01-01

    Advances in immunosuppressive therapy have significantly improved short-term allograft and patient survival.However,chronic allograft failure,antibody mediated rejection,recurrent diseases and immunosuppressive drug associated adverse effects remain serious barriers to long-term survival and quality of life.New immunosuppressive agents and protocols are being evaluated to combat these problems.Importantly,clinicians must work to manage post-transplant complications and avoid complex medication regimens,which will potentiate drug interactions and non.compliance.Different organs have different immunogenicities and each recipient has a unique clinical and immunologic profile.The clinician must recognize these variations and customize the immunosuppressive regimens and treatment protocols based on the individual condition.The general principles of an individualized immunosuppressive protocol should take the following factors into account:organ type,donor and recipient characteristics,quality of the donor organ,recipienVs medical history,recipient's undedying disease,immunologic risk for acute rejection,potential co-morbidity related to immunosuppression,significant druginteractions,medication costs and patient compliance.In addition,the combination of immunosuppressive drugs must have a pharmacologic rationale to achieve the desired goal of suppressing the individual's immune system to render the patient tolerant to the allograft while minimizing co-morbidities.For the past few years,many clinical strategies have been applied in an attempt to improve graft survival or to reduce immunsuppressants induced side-effects.Specific protocols include steroid or CNI avoidance,minimization or withdraw,desensitization,and treatment for antibody mediated rejection,disease specific,and pediatric specific.The short-term outcomes from these different strategies are promising but the long-term results remain to be determined.Unfortunately,current immunosuppressive agents or strategies

  20. Uncertainty Analyses and Strategy

    International Nuclear Information System (INIS)

    Kevin Coppersmith

    2001-01-01

    performance difficult. Likewise, a demonstration of the magnitude of conservatisms in the dose estimates that result from conservative inputs is difficult to determine. To respond to these issues, the DOE explored the significance of uncertainties and the magnitude of conservatisms in the SSPA Volumes 1 and 2 (BSC 2001 [DIRS 155950]; BSC 2001 [DIRS 154659]). The three main goals of this report are: (1) To briefly summarize and consolidate the discussion of much of the work that has been done over the past few years to evaluate, clarify, and improve the representation of uncertainties in the TSPA and performance projections for a potential repository. This report does not contain any new analyses of those uncertainties, but it summarizes in one place the main findings of that work. (2) To develop a strategy for how uncertainties may be handled in the TSPA and supporting analyses and models to support a License Application, should the site be recommended. It should be noted that the strategy outlined in this report is based on current information available to DOE. The strategy may be modified pending receipt of additional pertinent information, such as the Yucca Mountain Review Plan. (3) To discuss issues related to communication about uncertainties, and propose some approaches the DOE may use in the future to improve how it communicates uncertainty in its models and performance assessments to decision-makers and to technical audiences

  1. The Social Strategy Game

    Science.gov (United States)

    Gurven, Michael; Kaplan, Hillard; Winking, Jeffrey

    2010-01-01

    This paper examines social determinants of resource competition among Tsimane Amerindian women of Bolivia. We introduce a semi-anonymous experiment (the Social Strategy Game) designed to simulate resource competition among women. Information concerning dyadic social relationships and demographic data were collected to identify variables influencing resource competition intensity, as measured by the number of beads one woman took from another. Relationship variables are used to test how the affiliative or competitive aspects of dyads affect the extent of prosociality in the game. Using a mixed-modeling procedure, we find that women compete with those with whom they are quarreling over accusations of meat theft, mate competition, and rumor spreading. They also compete with members of their social network and with those who were designated as cooperative helpers or as close kin. Women take fewer beads from desired friends, neighbors, and from those viewed as enemies. We interpret favoritism toward enemies as resulting from fear of retribution. Our results suggest that social relations among women are multifaceted and often cannot be simplified by exclusive focus on genetic relatedness, physical proximity, or reciprocity. We argue that a complex understanding of cooperation and competition among women may require important contextual information concerning relationship history in addition to typical features of resource ecology. PMID:20526460

  2. LIMS strategy review

    International Nuclear Information System (INIS)

    Ibsen, T.G.

    1995-01-01

    The evaluation team found that the LABCORE program has a viable Laboratory Information Management System (LIMS) that will handle the sample tracking and reporting necessary to accomplish the requirements established by the system specifications. The team also found that the LABCORE program has made real accomplishments and that it has been moving in the right direction, for example the phased implementation at the 222-S laboratory. The LABCORE program has many strengths but it also has short comings that need to be addressed. The strengths are that the hardware, software, staff, and the computer and training facilities are all first rate. The shortcomings are that it is missing a strategy outlining the goals which would clearly define when the project implementation has been successfully completed. It also had excessive cost during its acquisition. Specific recommendations are made. As a whole, the evaluation team believes that LABCORE is the system that was specified and will meet the needs of both laboratories, 222-S and the Waste Sampling and Characterization Facility. LABCORE has experienced all the challenges of a new computer system but with continued effort on the part of the LABCORE team and laboratory personnel the system will operate as needed

  3. Lymphoma: Immune Evasion Strategies

    International Nuclear Information System (INIS)

    Upadhyay, Ranjan; Hammerich, Linda; Peng, Paul; Brown, Brian; Merad, Miriam; Brody, Joshua D.

    2015-01-01

    While the cellular origin of lymphoma is often characterized by chromosomal translocations and other genetic aberrations, its growth and development into a malignant neoplasm is highly dependent upon its ability to escape natural host defenses. Neoplastic cells interact with a variety of non-malignant cells in the tumor milieu to create an immunosuppressive microenvironment. The resulting functional impairment and dysregulation of tumor-associated immune cells not only allows for passive growth of the malignancy but may even provide active growth signals upon which the tumor subsequently becomes dependent. In the past decade, the success of immune checkpoint blockade and adoptive cell transfer for relapsed or refractory lymphomas has validated immunotherapy as a possible treatment cornerstone. Here, we review the mechanisms by which lymphomas have been found to evade and even reprogram the immune system, including alterations in surface molecules, recruitment of immunosuppressive subpopulations, and secretion of anti-inflammatory factors. A fundamental understanding of the immune evasion strategies utilized by lymphomas may lead to better prognostic markers and guide the development of targeted interventions that are both safer and more effective than current standards of care

  4. Gas strategies in Europe

    International Nuclear Information System (INIS)

    Le Floch-Prigent, L.

    1992-01-01

    The different factors affecting gas supply and demand in Europe are examined and the strategies considered necessary to ensure a successful European gas market in the 21st century are outlined. A number of conclusions are drawn. Even though a significant rise in the total demand for gas in Europe is forecast, there are enough sources to cover this demand. However, to think that this gas will be available at cheap conditions is an illusion. These sources are located further and further away which means that their costs will increase. Given the risks inherent in exploring, producing, transporting and marketing these reserves, all the concerned parties must be allowed an acceptable rate of return on their investment. The environmental positive assets inherent in natural gas will guarantee the industry a bright future if they can be fully exploited. New regulations must not hinder the development of new markets or the construction of new infrastructures. The transit directive already permits the softening of the rules regarding transportation; but in order for it to come into real effect there must be gas available on the market. (author)

  5. Management strategy of enterprise

    Directory of Open Access Journals (Sweden)

    Osovskiy O.A.

    2017-03-01

    Full Text Available The development of market relations, increasing competition result in the accelerated necessity in strategic management as one of the most efficient and progressive means of organization management. The article deals with such researching methods as SWOT analysis (studying strength and weak points, manufacturing feasibilities of an enterprise and threats caused by environment, BCG matrix (while determining marketing roles of output, Mack Kinsey (determining branch attraction, the tree of aims (looking for perspective directions of development, and also other well-known tools of strategic management. SE «Zhytomyr distillery» is the enterprise with over century traditions of production quality of its output. The results of the SWOT analysis has allowed to determine the lines of behavior due to favorable and unfavorable factors of environment. At present, the enterprise has much strength and manufacturing feasibilities, therefore, the principal directions of its activity have to become the improvement of its technological base, the expansion of output range and sale at the expense of free financial resources. The calculations made by the authors allowed them to develop the main strategies for development of an enterprise. The practical value of the calculations lies in keeping competitive lines both on the domestic market of Ukraine and on the foreign international market.

  6. Marketing Strategy and Implementation

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-05-31

    This report documents the marketing campaign that has been designed for middle and high school students in New Mexico to increase interest in participation in national security careers at the National Nuclear Security Administration. This marketing campaign builds on the research that was previously conducted, as well as the focus groups that were conducted. This work is a part of the National Nuclear Security Preparedness Project (NSPP) being performed under a Department of Energy (DOE) / National Nuclear Security Administration (NNSA) grant. Outcome analysis was performed to determine appropriate marketing strategies. The analysis was based upon focus groups with middle school and high school students, student interactions, and surveys completed by students to understand and gauge student interest in Science, Technology, Engineering, and Math (STEM) subjects, interest in careers at NNSA, future job considerations, and student desire to pursue post-secondary education. Further, through the focus groups, students were asked to attend a presentation on NNSA job opportunities and employee requirements. The feedback received from the students was utilized to develop the focus and components of the marketing campaign.

  7. Local strategies for decontamination

    Energy Technology Data Exchange (ETDEWEB)

    Hubert, P [Institut de Protection et de Surete Nucleaire, Fontenay-aux-Roses cedex (France); Ramzaev, V [Branch of Institute of Radiation Hygiene, Novozybkov, Bryansk region (Russian Federation); Antsypov, G [Chernnobyl State Committee of the Republic of Belarus, Minsk (Belarus); Sobotovich, E [Institute of Geochemistry, Mineralogy and Ore formation, Kiev (Ukraine); Anisimova, L [EMERCOM, Moscow (Russian Federation)

    1996-07-01

    The efficiencies of a great number of techniques for decontamination or dose reduction in contaminated areas have been investigated by several teams of E.C. and CIS scientists (ECP4 project). Modelling, laboratory and field experiments, t and return from experience allowed to assess radiological efficiencies (e.g. 'decontamination factor') and requirements for the operation of numerous practical solutions. Then, those data were supplemented with data on cost and waste generation in order to elaborate all the information for the optimization of decontamination strategies. Results will be presented for about 70 techniques. However, a technique cannot be compared to another from a generic point of view. Rather it is designed for a specific target and the best technology depends on the objectives. It has been decided to implement decision analyses on case studies, and the local conditions and objectives have been investigated. Individual doses ranged from 1 to 5 mSv, with contrasted contributions of internal and external doses. The desire to restore a normal activity in a partially depopulated settlement, and concerns about the recent increase in internal doses were typical incentives for action. The decision aiding analysis illustrated that actions can be usually recommended. Results are outlined here.

  8. Empathic design: Research strategies

    Directory of Open Access Journals (Sweden)

    Joyce Thomas

    2013-01-01

    Full Text Available This paper explores the role of empathy within new product development from the perspective of human-centred design. The authors have developed a range of empathic design tools and strategies that help to identify authentic human needs.For products and services to be effective, they need to satisfy both functional and emotional needs of individuals. In addition, the individual user needs to feel that the product and/or service has been designed ‘just for them’, otherwise they may misuse, underuse or abandon the product/service. This becomes critical with a product such as a Zimmer frame (walker, when it fails to resonate with the patient due to any stigma the patient may perceive, and thus remains unused.When training young designers to consider the wider community (people unlike themselves during the design process, it has proven extremely valuable to take them outside their comfort zones, by seeking to develop empathy with the end user for whom they are designing. Empathic modelling offers designers the opportunity to develop greater insight and understanding, in order to support more effective design outcomes. Sensitising designers to the different ways that individuals complete daily tasks has helped to diminish the gap between themselves and others (e.g. people with disabilities.The authors intend for this paper to resonate with health care providers. Human-centred design can help to refocus the designer, by placing the individual end user’s needs at the heart of their decision-making.

  9. Empathic design: Research strategies.

    Science.gov (United States)

    Thomas, Joyce; McDonagh, Deana

    2013-01-01

    This paper explores the role of empathy within new product development from the perspective of human-centred design. The authors have developed a range of empathic design tools and strategies that help to identify authentic human needs.For products and services to be effective, they need to satisfy both functional and emotional needs of individuals. In addition, the individual user needs to feel that the product and/or service has been designed 'just for them', otherwise they may misuse, underuse or abandon the product/service. This becomes critical with a product such as a Zimmer frame (walker), when it fails to resonate with the patient due to any stigma the patient may perceive, and thus remains unused.When training young designers to consider the wider community (people unlike themselves) during the design process, it has proven extremely valuable to take them outside their comfort zones, by seeking to develop empathy with the end user for whom they are designing. Empathic modelling offers designers the opportunity to develop greater insight and understanding, in order to support more effective design outcomes. Sensitising designers to the different ways that individuals complete daily tasks has helped to diminish the gap between themselves and others (e.g. people with disabilities).The authors intend for this paper to resonate with health care providers. Human-centred design can help to refocus the designer, by placing the individual end user's needs at the heart of their decision-making.

  10. Tenable world strategies

    Energy Technology Data Exchange (ETDEWEB)

    Meadows, D.L. (New Hampshire Univ. (USA). Inst. for Policy and Social Science Research)

    1991-10-01

    The Author presents several arguments explaining and backing the mechanics of a world strategy of zero growth. First, attention is brought to Aurelio Peccei's concerns regarding the short-sightedness of the energy and economic policies of industrialized nations. In his book (entitled 'Verso l'Abisso'), written almost 25 years ago, he correctly predicted the severity and timing of current global environmental problems such as the greenhouse effect and acid rain. Urgent and concerted action by world governments is recommended to contain and and remedy damage being caused by a diverse mix of integrated factors - over-population, uncontrolled food production, pollution, over-production by industry, and the improper use of energy and other natural resources. The Author sets guidelines for the creation of a world of steady-state growth in which an equilibrium is reached between overall standards of living and population dynamics. To meet this goal of global man/environment peaceful coexistence, he strongly urges the creation and instillation of a new set of values through the placing of emphasis on the research and development of cultural, psychological, institutional and moral philosophies which, in the last century, have been almost entirely supplanted world-wide by growing materialistic ideals and the pursuit of technological perfection.

  11. PA strategies in Korea

    International Nuclear Information System (INIS)

    Chung, J.K.

    1998-01-01

    The main purpose of promoting nuclear public acceptance in Korea is to secure necessary sites for construction of large nuclear facilities in a timely manner. Another important purpose is to maintain a good neighbor relationship between the operator of nuclear facilities and local population. To promote better understanding about the nation's peaceful nuclear programs to the general public is another facet of nuclear information activities. However, opposition by the local population living around the nuclear facilities has always been aggressive. The primary concern of the local population is basically focused on the financial issues. Professional nationwide anti-nuclear groups are abetting the local population directly but with fabricated information in order to increase psychological fears. In an effort to compensate for the psychological and sociological burdens of the local population, the Korean government arranged legal provisions. To this end, beginning in 1990, community support programs have been implemented. As the nation's nuclear power program expanded, anti-nuclear activities also became very active. Public information programs should be expanded. Some highlights of public acceptance programs of the nuclear industries are 'Go and Meet' rather than 'Come and See', 'Act rather than react', 'Proper messages to proper target groups', 'Maximum use of the third party communicators', and so on. An orchestrated effort among the nation's nuclear industries is essential to the successful implementation of the PA strategies. (author)

  12. Lymphoma: Immune Evasion Strategies

    Energy Technology Data Exchange (ETDEWEB)

    Upadhyay, Ranjan; Hammerich, Linda; Peng, Paul [Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 (United States); Brown, Brian [Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 (United States); Merad, Miriam [Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 (United States); Brody, Joshua D., E-mail: joshua.brody@mssm.edu [Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 (United States)

    2015-04-30

    While the cellular origin of lymphoma is often characterized by chromosomal translocations and other genetic aberrations, its growth and development into a malignant neoplasm is highly dependent upon its ability to escape natural host defenses. Neoplastic cells interact with a variety of non-malignant cells in the tumor milieu to create an immunosuppressive microenvironment. The resulting functional impairment and dysregulation of tumor-associated immune cells not only allows for passive growth of the malignancy but may even provide active growth signals upon which the tumor subsequently becomes dependent. In the past decade, the success of immune checkpoint blockade and adoptive cell transfer for relapsed or refractory lymphomas has validated immunotherapy as a possible treatment cornerstone. Here, we review the mechanisms by which lymphomas have been found to evade and even reprogram the immune system, including alterations in surface molecules, recruitment of immunosuppressive subpopulations, and secretion of anti-inflammatory factors. A fundamental understanding of the immune evasion strategies utilized by lymphomas may lead to better prognostic markers and guide the development of targeted interventions that are both safer and more effective than current standards of care.

  13. Local strategies for decontamination

    International Nuclear Information System (INIS)

    Hubert, P.; Ramzaev, V.; Antsypov, G.; Sobotovich, E.; Anisimova, L.

    1996-01-01

    The efficiencies of a great number of techniques for decontamination or dose reduction in contaminated areas have been investigated by several teams of E.C. and CIS scientists (ECP4 project). Modelling, laboratory and field experiments, t and return from experience allowed to assess radiological efficiencies (e.g. 'decontamination factor') and requirements for the operation of numerous practical solutions. Then, those data were supplemented with data on cost and waste generation in order to elaborate all the information for the optimization of decontamination strategies. Results will be presented for about 70 techniques. However, a technique cannot be compared to another from a generic point of view. Rather it is designed for a specific target and the best technology depends on the objectives. It has been decided to implement decision analyses on case studies, and the local conditions and objectives have been investigated. Individual doses ranged from 1 to 5 mSv, with contrasted contributions of internal and external doses. The desire to restore a normal activity in a partially depopulated settlement, and concerns about the recent increase in internal doses were typical incentives for action. The decision aiding analysis illustrated that actions can be usually recommended. Results are outlined here

  14. Non-oblivious Strategy Improvement

    Science.gov (United States)

    Fearnley, John

    We study strategy improvement algorithms for mean-payoff and parity games. We describe a structural property of these games, and we show that these structures can affect the behaviour of strategy improvement. We show how awareness of these structures can be used to accelerate strategy improvement algorithms. We call our algorithms non-oblivious because they remember properties of the game that they have discovered in previous iterations. We show that non-oblivious strategy improvement algorithms perform well on examples that are known to be hard for oblivious strategy improvement. Hence, we argue that previous strategy improvement algorithms fail because they ignore the structural properties of the game that they are solving.

  15. Strategic Audit and Ownership Strategy

    Directory of Open Access Journals (Sweden)

    Mike Franz Wahl

    2015-10-01

    Full Text Available In the new global economy, ownership has become a central issue for organizational performance. Ownership strategy is where corporate governance meets strategic management. Highlighting a knowledge gap in the field of corporate governance, the author is asking the central research question: “how to develop an ownership strategy?” The main purpose of this paper is to answer this original question and develop a better understanding about ownership strategies. Theoretically there is evidence to indicate that there is a link between strategic audit and ownership strategy. Analyzing firm cases from Estonia allows concluding that the strategic audit is useful for developing systemically ownership strategies, which in turn could be a realistic alternative for complete contracts. The use of strategic audits gives the business owner an opportunity to analyze his own actions and behavior, learning, managing knowledge, and finally clearly expressing his will in the form of an ownership strategy.

  16. The office of strategy management.

    Science.gov (United States)

    Kaplan, Robert S; Norton, David P

    2005-10-01

    There is a disconnect in most companies between strategy formulation and strategy execution. On average, 95% of a company's employees are unaware of, or do not understand, its strategy. If employees are unaware of the strategy, they surely cannot help the organization implement it effectively. It doesn't have to be like this. For the past 15 years, the authors have studied companies that achieved performance breakthroughs by adopting the Balanced Scorecard and its associated tools to help them better communicate strategy to their employees and to guide and monitor the execution of that strategy. Some companies, of course, have achieved better, longer-lasting improvements than others. The organizations that have managed to sustain their strategic focus have typically established a new corporate-level unit to oversee all activities related to strategy: an office of strategy management (OS M). The OSM, in effect, acts as the CEO's chief of staff. It coordinates an array of tasks: communicating corporate strategy; ensuring that enterprise-level plans are translated into the plans of the various units and departments; executing strategic initiatives to deliver on the grand design; aligning employees' plans for competency development with strategic objectives; and testing and adapting the strategy to stay abreast of the competition. The OSM does not do all the work, but it facilitates the processes so that strategy is executed in an integrated fashion across the enterprise. Although the companies that Kaplan and Norton studied use the Balanced Scorecard as the framework for their strategy management systems, the authors say the lessons of the OSM are applicable even to companies that do not use it.

  17. Communication: essential strategies for success.

    Science.gov (United States)

    O'Connor, Mary

    2013-06-01

    This department highlights change management strategies that may be successful in strategically planning and executing organizational change initiatives. With the goal of presenting practical approaches helpful to nurse leaders advance organizational change, content includes evidence-based projects, tool, and resources that mobilize and sustain organizational change initiatives. In this article, the author discusses strategies for communication for change processes, whether large or small. Intentional planning and development of a communication strategy alongside, not as an afterthought, to change initiatives are essential.

  18. Formasi Strategi Di Organisasi Profesional

    OpenAIRE

    Jane, Orpha

    2011-01-01

    Strategy formation within every organization has a unique characteristics. Profes-sional organizations are an organization that contains number of individuals with aspecific competency and capability. Also its have a structure with a team of expertrather than technostructure. This type of organization, all the member of the organi-zations are involved in formulating the strategy. Top leader has a role as coordinatorin formulating and executing the strategy.

  19. Marketing Strategy for Merchant Shipbuilders

    Science.gov (United States)

    1995-01-01

    1995 Ship Production Symposium Paper No. 26: Marketing Strategy for Merchant Shipbuilders U.S. DEPARTMENT OF THE NAVY CARDEROCK DIVISION, NAVAL...Production Symposium Paper No. 26: Marketing Strategy for Merchant Shipbuilders 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6... Marketing Strategy for Merchant Shipbuilders Paul W. Stott (V), A&P Appledore international, U.K. ABSTRACT Much has been published over the years about

  20. A Taxonomy of Manufacturing Strategies

    OpenAIRE

    Jeffrey G. Miller; Aleda V. Roth

    1994-01-01

    This paper describes the development and analysis of a numerical taxonomy of manufacturing strategies. The taxonomy was developed with standard methods of cluster analysis, and is based on the relative importance attached to eleven competitive capabilities defining the manufacturing task of 164 large American manufacturing business units. Three distinct clusters of manufacturing strategy groups were observed. Though there is an industry effect, all three manufacturing strategy types are obser...

  1. Determinants of contractor pricing strategy

    OpenAIRE

    Moses, O. Douglas

    1988-01-01

    This paper investigates pricing strategies used by major defense contractors. Two pricing strategies are identified and discussed: penetration, which calls for a relatively low initial price followed by little reduction in price over time, and skimming, which calls for a relatively high initial price coupled with greater reduction in price over time. It is argued that contractor pricing strategy will depend on features of the defense program under consideration and featur...

  2. Energy policy, strategies for uncertainty

    International Nuclear Information System (INIS)

    Cook, P.L.; Surrey, A.J.

    1977-01-01

    The subject is dealt with in chapters, entitled: energy policy-objectives, strategies and policies; the 1967 fuel policy; problems of the optimising approach; the uncertain outlook; oil; coal; gas; electricity; the interdependence of the four fuel industries; energy policy for the future - the need for a long-term strategy; medium-term strategies and short-term policies; the organisational decisions of energy policy. Nuclear power is included in the subject matter. (U.K.)

  3. The processes of strategy development

    OpenAIRE

    Bailey, Andy; Johnson, Gerry

    1995-01-01

    This paper is concerned with the processes by which strategy is developed within organisations. It builds on research into the nature of strategy development being undertaken within the Centre for Strategic Management and Organisational Change at Cranfield School of Management. Initially the process of strategy development is discussed, a number of explanations of the process are presented and an integrated framework is developed. This framework is subsequently used to illustra...

  4. Niche-specific cognitive strategies

    DEFF Research Database (Denmark)

    Hulgard, K.; Ratcliffe, J. M.

    2014-01-01

    Related species with different diets are predicted to rely on different cognitive strategies: those best suited for locating available and appropriate foods. Here we tested two predictions of the niche-specific cognitive strategies hypothesis in bats, which suggests that predatory species should...... the niche-specific cognitive strategies hypothesis and suggest that for gleaning and clutter-resistant aerial hawking bats, learning to associate shape with food interferes with subsequent spatial memory learning....

  5. Implementing marketing strategy (Part four).

    Science.gov (United States)

    Dodson, D C; Dotson, M; McIlwain, T F; Young, D

    1993-01-01

    Every organization must monitor and evaluate the performance of its marketing strategies. The health care marketer must continually develop effective measures related to outcomes so that marketing efforts can be justified and garnish the support and resources they deserve. A major task for the marketing executive for the next decade is to develop marketing strategies and prove that those strategies are being met and that they help the health care organization carry out its objective to meet its mission.

  6. STRATEGIES FOR ACHIEVING COMPETITIVE ADVANTAGE

    OpenAIRE

    Jusuf ZEKIRI; Alexandru NEDELEA

    2011-01-01

    This paper is organized in three parts. A brief overview of the importance of strategies within companies, as well as literature review is presented along with traditional approaches on strategies for achieving competitive advantage, and new approaches for gaining a competitive advantage. The main objective of the paper is to outline and discuss the relevant issues and challenges from a theoretical viewpoint related with the possible strategy formulation of companies in order to achieve a com...

  7. Strategy Assessment of Company ECOPOSTES

    OpenAIRE

    Cortazar Sanabria, Javier Mauricio

    2015-01-01

    This thesis focuses on developing a research on the different types of strategies a company can implement depending on their situation and the various analyses that must be completed before making the strategy decision. External and internal environment methods are described together with the various forms of corporate restructure methods a company can use if needed. The whole process is followed step by step to provide a strategy assessment to company Ecopostes, a Colombian company focused o...

  8. Clarkesville Green Infrastructure Implementation Strategy

    Science.gov (United States)

    The report outlines the 2012 technical assistance for Clarkesville, GA to develop a Green Infrastructure Implementation Strategy, which provides the basic building blocks for a green infrastructure plan:

  9. Involving Employees in Strategy innovation

    DEFF Research Database (Denmark)

    Friis, Ole Uhrskov; Koch, Christian

    2011-01-01

    Strategy as a practice and continuous innovation approaches are combined to conceptualise dilemmas of short versus long term and to analyse a case of employee participation as a particular example of strategy innovation. The case is a medium size textile company developing its strategy involving ...... and Balanced Score Card consultancy, an ‘open space’ workshop and organized strategy projects. Especially the latter two are important in facilitating the employee involvement. The case however also exhibit enterprise situated praxis’s like mitigation of taboos....

  10. STRATEGI PROMOSI EVENT NAMASTE FESTIVAL

    Directory of Open Access Journals (Sweden)

    Arie Wibowo

    2015-11-01

    Full Text Available Promotion Strategy is the method that you use to promote the product. If we use the wrong promotion strategy, it will bring the disadvantage for the product and company. And on the contrary, if we are using the right promotion strategy, then it will bring the benefit for the product selling as did by Namaste Festival Event. This research was conducted in order to discover how promotion strategy of Namaste Festival Event to attract Yoga market by using promotion strategy theory. This research was guided by a qualitative approach with descriptive research in particular. The method being used was case study by conducting in-depth interviews. This research enabled the writer to discuss about the promotion strategy that being used by Namaste Festival event to increase the number of visitor. Therefore the researcher will able to get view on how PT Namaste Jaya Aditi as the organizer could run the promotion to get high number of visitor. After conducting an analysis, the main conclusion of this research is that the promotion strategy that been used by Namaste Festival organize is integrated several promotion activities such as online marketing, pre event road show, selling promotion, advertising (television and media printing & publicity. The result of this research is also said that promotion strategy that been use has an important role to attract visitor to participate in the event. Strategi Promosi adalah metode yang Anda gunakan untuk mempromosikan produk. Jika kita menggunakan strategi promosi yang salah, maka akan membawa kerugian bagi produk dan perusahaan. Dan sebaliknya, jika kita menggunakan strategi promosi yang tepat, maka akan membawa keuntungan bagi penjualan produk seperti yang dilakukan oleh Namaste Festival Event. Penelitian ini dilakukan untuk mengetahui bagaimana strategi promosi Namaste Festival Event untuk menarik pasar Yoga dengan menggunakan teori strategi promosi. Penelitian ini dipandu oleh pendekatan kualitatif dengan

  11. Strategi Permintaan dalam Bahasa Jepang

    Directory of Open Access Journals (Sweden)

    Timur Sri Astami

    2015-01-01

    Full Text Available Request strategy in Japanese serves to present desires to hearer and speaker gets benefit from the request. Request strategy consists of bald on record, on record with positive politeness, on record with negative politeness, and off record. Research used qualitative descriptive approach. Data were gathered from Maya Koikeda’s Tokimeki Makkun comic book. Research, in the corpus of data, found bald on record strategy was a strategy without any strings attached. Then, on record with positive politeness was showed by the closeness and solidarity relationship. While on record with negative politeness was showed by minimizing load demand and apology, and off record with a vague ellipsis sentence. 

  12. Strategy Use and Strategy Choice in Fraction Magnitude Comparison

    Science.gov (United States)

    Fazio, Lisa K.; DeWolf, Melissa; Siegler, Robert S.

    2016-01-01

    We examined, on a trial-by-trial basis, fraction magnitude comparison strategies of adults with more and less mathematical knowledge. College students with high mathematical proficiency used a large variety of strategies that were well tailored to the characteristics of the problems and that were guaranteed to yield correct performance if executed…

  13. Mapping your innovation strategy.

    Science.gov (United States)

    Anthony, Scott D; Eyring, Matt; Gibson, Lib

    2006-05-01

    In the complex sport of American football, teams rely on playbooks as thick as the Manhattan phone directory. But when it comes to creating innovative growth businesses-which is at least as complicated as professional football--most companies have not developed detailed game plans. Indeed, many managers have concluded that a fog enshrouds the world of innovation, obscuring high-potential opportunities. The authors believe that companies can penetrate that fog by developing growth strategies based on disruptive innovations, as defined by Clayton Christensen. Such innovations conform to a pattern: They offer an entirely new solution; they perform adequately along traditional dimensions and much better along other dimensions that matter more to target customers; and they are not initially appealing to powerful incumbents. Companies can develop customized checklists, or playbooks, by combining this basic pattern with analysis of major innovations in their markets. The key early on is to focus not on detailed financial estimates--which will always guide companies toward the markets most hostile to disruptive innovations--but on how well the innovation fits the pattern of success. It's also crucial to encourage flexibility: Companies must be willing to kill projects that are going nowhere, exempt innovations from standard development processes, and avoid burdening project teams with extra financing, which can keep them heading in the wrong direction. Companies can create competitive advantage by becoming champions at defining the pattern of successful innovations and executing against it. But as that pattern becomes obvious--and others emerge-building a sustainable advantage on innovation competencies will again prove elusive.

  14. Marketing Strategy and Implementation

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2010-09-30

    This report documents the preparation of materials for the marketing campaign that has been designed for middle and high school students in New Mexico to increase interest in participation in national security careers at the National Nuclear Security Administration. The materials and the marketing campaign build on the research that was previously completed, as well as the focus groups that were conducted. This work is a part of the National Nuclear Security Preparedness Project (NSPP). Previous research included outcome analysis to determine appropriate marketing strategies. The analysis was based upon focus groups with middle school and high school students, student interactions, and surveys completed by students to understand and gauge student interest in Science, Technology, Engineering, and Math (STEM) subjects, interest in careers at NNSA, future job considerations, and student desire to pursue post-secondary education. Further, through the focus groups, students were asked to attend a presentation on NNSA job opportunities and employee requirements. The feedback received from the students was utilized to develop the focus and components of a marketing campaign divided into DISCO (Discovering Intelligence and Security Career Opportunities) for the middle school age group and DISCO…..Your Way! for high school age groups. Both campaigns have an intertwined message that focuses on the education of students in the various national security career opportunities at NNSA using the STEM concepts and the notion that almost any career they can think of has a fit within NNSA. Further, a special emphasis has been placed on the importance of obtaining a national security clearance when working at NNSA and the steps that will need to be taken during middle school, high school, and college to be allowed this opportunity.

  15. Blue ocean strategy.

    Science.gov (United States)

    Kim, W Chan; Mauborgne, Renée

    2004-10-01

    Despite a long-term decline in the circus industry, Cirque du Soleil profitably increased revenue 22-fold over the last ten years by reinventing the circus. Rather than competing within the confines of the existing industry or trying to steal customers from rivals, Cirque developed uncontested market space that made the competition irrelevant. Cirque created what the authors call a blue ocean, a previously unknown market space. In blue oceans, demand is created rather than fought over. There is ample opportunity for growth that is both profitable and rapid. In red oceans--that is, in all the industries already existing--companies compete by grabbing for a greater share of limited demand. As the market space gets more crowded, prospects for profits and growth decline. Products turn into commodities, and increasing competition turns the water bloody. There are two ways to create blue oceans. One is to launch completely new industries, as eBay did with online auctions. But it's much more common for a blue ocean to be created from within a red ocean when a company expands the boundaries of an existing industry. In studying more than 150 blue ocean creations in over 30 industries, the authors observed that the traditional units of strategic analysis--company and industry--are of limited use in explaining how and why blue oceans are created. The most appropriate unit of analysis is the strategic move, the set of managerial actions and decisions involved in making a major market-creating business offering. Creating blue oceans builds brands. So powerful is blue ocean strategy, in fact, that a blue ocean strategic move can create brand equity that lasts for decades.

  16. Vaccine strategies against schistosomiasis

    Directory of Open Access Journals (Sweden)

    A. Capron

    1992-01-01

    Full Text Available Schistosomiasis, the second major parasitic disease in the world after malaria affects at least 200 million people, 500 million being exposed to the risk of infection. It is widely agreed that a vaccine strategy wich could lead to the induction of effector mechanisms reducing the level of reinfection and ideally parasite fecundity would deeply affect the incidence of pathological manifestations as well as the parasite transmission potentialities. Extensive studies performed in the rat model have allowed the identification of novel effector mechanisms involving IgE antibodies and various inflammatory cell populations (eosinophils, macrophages and platelets whereas regulation of immune response by blocking antibodies has been evidencial. Recent epidemiological studies have now entirely confirmed in human populations the the role of IgE antibodies in the acquisition of resistance and the association of IgG4 blocking antibodies with increased susceptibility. On the basis of these concepts, several schistosome glutathion S-transferase (Sm 28 GST appears as a pronising vaccine candidate. Immunization experiments have shown that two complementary goals can be achieved: (a a partial but significant reduction of the worm population (up to 60//in rats; (b a significant reduction of parasite fecundity (up in the mice and 85//in cattle and egg viability (up to 80//. At least two distinct immunological mechanisms account for these two effects. IgE antibodies appear as a major humoral component of acquired resistance whereas IgA antibodies appear as a major humoral factor affecting parasite fecundity. These studies seem to represent a parasite diseases through the identification of potentially protective antigens and of the components of the immune response which vaccination should aim at inducing.

  17. Strategies for safe motherhood.

    Science.gov (United States)

    Chatterjee, A

    1995-02-01

    The Safe Motherhood Initiative was launched in 1988 as a global effort to halve maternal mortality and morbidity by the year 2000. The program uses a combination of health and nonhealth strategies to emphasize the need for maternal health services, extend family planning services, and improve the status of women. The maternal mortality rate (per 100,000 live births) is 390 for the world, 20-30 for developed countries, 450 for developing countries, and 420 for Asia. This translates into 308,000 maternal deaths in Asia, of which 100,000 occur in India. The direct causes of maternal mortality include sepsis, hemorrhage, eclampsia, and ruptured uterus. Indirect causes occur when associated medical conditions, such as anemia and jaundice, are exacerbated by pregnancy. Underlying causes are ineffective health services, inadequate obstetric care, unregulated fertility, infections, illiteracy, early marriage, poverty, malnutrition, and ignorance. India's Child Survival and Safe Motherhood Program seeks to achieve immediate improvements by improving health care. Longterm improvements will occur as nutrition, income, education, and the status of women improve. Improvements in health care will occur in through the provision of 1) essential obstetric care for all women (which will be essentially designed for low-risk women), 2) early detection of complications during pregnancy and labor, and 3) emergency services. Services will be provided to pregnant women at their door by field staff, at a first referral hospital, perhaps at maternity villages where high risk cases can be housed in the latter part of their pregnancies, and through the continual accessibility of government vehicles. In addition, family planning services will be improved so that fertility regulation can have its expected beneficial effect on the maternal mortality rate. The professional health organizations in India will also play a vital role in the success of this effort to reduce maternal mortality.

  18. Strategy as active waiting.

    Science.gov (United States)

    Sull, Donald N

    2005-09-01

    Successful executives who cut their teeth in stable industries or in developed countries often stumble when they face more volatile markets. They falter, in part, because they assume they can gaze deep into the future and develop a long-term strategy that will confer a sustainable competitive advantage. But visibility into the future of volatile markets is sharply limited because so many different variables are in play. Factors such as technological innovation, customers' evolving needs, government policy, and changes in the capital markets interact with one another to create unexpected outcomes. Over the past six years, Donald Sull, an associate professor at London Business School, has led a research project examining some of the world's most volatile markets, from national markets like China and Brazil to industries like enterprise software, telecommunications, and airlines. One of the most striking findings from this research is the importance of taking action during comparative lulls in the storm. Huge business opportunities are relatively rare; they come along only once or twice in a decade. And, for the most part, companies can't manufacture those opportunities; changes in the external environment converge to make them happen. What managers can do is prepare for these golden opportunities by managing smart during the comparative calm of business as usual. During these periods of active waiting, leaders must probe the future and remain alert to anomalies that signal potential threats or opportunities; exercise restraint to preserve their war chests; and maintain discipline to keep the troops battle ready. When a golden opportunity or"sudden death"threat emerges, managers must have the courage to declare the main effort and concentrate resources to seize the moment.

  19. STRATEGI PENGEMBANGAN INDUSTRI KECIL CARICA

    Directory of Open Access Journals (Sweden)

    Adi Permadi

    2015-03-01

    Full Text Available Tujuan penelitian ini untuk mengetahui bagaimana profil industri kecil carica di Kabupaten Wonosobo serta untuk mengetahui strategi pengembangan apa yang bisa digunakan. Variabel yang diteliti adalah profil industri yang meliputi sumber daya manusia, permodalan, teknologi, dan pemasaran. Metode analisis data yang digunakan adalah metode analisis deskriptif dan analisis SWOT. Berdasarkan hasil penelitian menunjukkan bahwa profil industri kecil carica di Kabupaten Wonosobo pada tahun 2014 ada 15 unit usaha. Ada beberapa prioritas strategi pengembangan yaang dilakukaan yaitu strategi SO dengan meningkatkan kualitas SDM, memanfaatkan tenaga kerja dari daerah sekitar, dan mengoptimalkan lokasi industri yang strategis. Strategi WO menyiapkan stok produk carica, mengoptimalkan produk carica, dan mengoptimalkan pelatihan dari dinas terkait. Strategi ST dengan meningkatkan kualitas ciri khas produk carica,peranan pemerintah dalam hal mengantisipasi bencana longsor di Dieng, dan melakukan inovasi produk carica. Strategi WT dengan meningkatkan kemampuan manajerial pengusaha, menaikkan harga jual produk carica, dan pada musim kemarau diganti dengan produk makanan komoditas Kabupaten Wonosobo. Berdasarkan hasil penelitian, strategi yang diterapkan dalam kondisi ini adalah mendukung kebijakan yang agresif, yaitu industri kecil carica di Kabupaten Wonosobo dapat bersaing dengan produk olahan makanan jenis lainnya dari berbagai daerah dengan cara menjaga dan meningkatkan kualitas produk carica yang dihasilkan.The purpose of this study to find out the profiles of carica industries in Wonosobo regency and to determine what is the development strategy can be used. The variables in this research belongs to human resources, capital, technology, and marketing. Data analysis method used is descriptive analysis method and SWOT analysis. Based on the results of this study showed that small industrial profiles carica in Wonosobo regency in 2014 there were 15 business

  20. Making strategy: learning by doing.

    Science.gov (United States)

    Christensen, C M

    1997-01-01

    Companies find it difficult to change strategy for many reasons, but one stands out: strategic thinking is not a core managerial competence at most companies. Executives hone their capabilities by tackling problems over and over again. Changing strategy, however, is not usually a task that they face repeatedly. Once companies have found a strategy that works, they want to use it, not change it. Consequently, most managers do not develop a competence in strategic thinking. This Manager's Tool Kit presents a three-stage method executives can use to conceive and implement a creative and coherent strategy themselves. The first stage is to identify and map the driving forces that the company needs to address. The process of mapping provides strategy-making teams with visual representations of team members' assumptions, those pictures, in turn, enable managers to achieve consensus in determining the driving forces. Once a senior management team has formulated a new strategy, it must align the strategy with the company's resource-allocation process to make implementation possible. Senior management teams can translate their strategy into action by using aggregate project planning. And management teams that link strategy and innovation through that planning process will develop a competence in implementing strategic change. The author guides the reader through the three stages of strategy making by examining the case of a manufacturing company that was losing ground to competitors. After mapping the driving forces, the company's senior managers were able to devise a new strategy that allowed the business to maintain a competitive advantage in its industry.

  1. Learning Strategy Instruction Innovation Configuration

    Science.gov (United States)

    Schumaker, Jean B.

    2011-01-01

    One way of helping students with learning disabilities and other struggling students to be independent life-long learners is to teach them how to use learning strategies in efficient ways. Learning strategy instruction can provide students the opportunity to succeed in today's schools and meet rigorous standards, transforming ineffective learners…

  2. Teaching Strategies for Specialized Ensembles.

    Science.gov (United States)

    Teaching Music, 1999

    1999-01-01

    Provides a strategy, from the book "Strategies for Teaching Specialized Ensembles," that addresses Standard 9A of the National Standards for Music Education. Explains that students will identify and describe the musical and historical characteristics of the classical era in music they perform and in audio examples. (CMK)

  3. National Drug Control Strategy, 2011

    Science.gov (United States)

    Office of National Drug Control Policy, 2011

    2011-01-01

    In May of 2010, President Obama released the Administration's inaugural "National Drug Control Strategy". Based on the premise that drug use and its consequences pose a threat not just to public safety, but also to public health, the 2010 "Strategy" represented the first comprehensive rebalancing of Federal drug control policy in the nearly 40…

  4. Strategy Formation in an Adhocracy.

    Science.gov (United States)

    Mintzberg, Henry; McHugh, Alexandra

    1985-01-01

    This paper identifies and tracks the strategies pursued by a single-project organization, the National Film Board, across almost four decades of its history. Findings focus on three themes: the emergent nature of the organization's strategies, its cycles of behavior, and the organization's quest for "adhocracy." (TE)

  5. National Drug Control Strategy. Update.

    Science.gov (United States)

    Office of National Drug Control Policy, Washington, DC.

    President Bush's new National Drug Control Strategy for 2003 focuses on three core priorities: stopping drug use before it starts; healing America's drug users; and disrupting the market. The 2003 strategy reports progress toward meeting the President's goals of reducing drug use by 10 percent over 2 years, and 25 percent over 5 years. With regard…

  6. On American Cultural Exportation Strategy

    Institute of Scientific and Technical Information of China (English)

    李德俊

    2015-01-01

    American government has been attaching great importance to the role that cultural values plays in international relationships and Culture Exportation has gradually become one of the important parts of American diplomatic strategy. This strategy,which is propelled by a variety of impetuses and conducted by different approaches,is mainly aimed to serve the overall national interests of the United States.

  7. On American Cultural Exportation Strategy

    Institute of Scientific and Technical Information of China (English)

    李德俊

    2015-01-01

    American government has been attaching great importance to the role that cultural values plays in international relationships and Culture Exportation has gradually become one of the important parts of American diplomatic strategy.This strategy,which is propelled by a variety of impetuses and conducted by different approaches,is mainly aimed to serve the overall national interests of the United States.

  8. Hemodialysis: stressors and coping strategies.

    Science.gov (United States)

    Ahmad, Muayyad M; Al Nazly, Eman K

    2015-01-01

    End-stage renal disease (ESRD) is an irreversible and life-threatening condition. In Jordan, the number of ESRD patients treated with hemodialysis is on the rise. Identifying stressors and coping strategies used by patients with ESRD may help nurses and health care providers to gain a clearer understanding of the condition of these patients and thus institute effective care planning. The purpose of this study was to identify stressors perceived by Jordanian patients on hemodialysis, and the coping strategies used by them. A convenience sample of 131 Jordanian men and women was recruited from outpatients' dialysis units in four hospitals. Stressors perceived by participants on hemodialysis and the coping strategies were measured using Hemodialysis Stressor Scale, and Ways of Coping Scale-Revised. Findings showed that patients on hemodialysis psychosocial stressors scores mean was higher than the physiological stressors mean. Positive reappraisal coping strategy had the highest mean among the coping strategies and the lowest mean was accepting responsibility. Attention should be focused towards the psychosocial stressors of patients on hemodialysis and also helping patients utilize the coping strategies that help to alleviate the stressors. The most used coping strategy was positive reappraisal strategy which includes faith and prayer.

  9. MUET Preparation Language Learning Strategies

    Science.gov (United States)

    Kuen, Yoong Li; Embi, Mohamed Amin

    2012-01-01

    The main objective of the study was to examine the English language learning strategies (LLS) used by Lower Six students in secondary schools who are sitting for their MUET test. It analyzed the language learning strategies that students use in order to prepare for the MUET test. Data were collected using a survey questionnaire with 300 students.…

  10. Math Fact Strategies Research Project

    Science.gov (United States)

    Boso, Annie

    2011-01-01

    An action research project was conducted in order to determine effective math fact strategies for first graders. The traditional way of teaching math facts included using timed tests and flashcards, with most students counting on their fingers or a number line. Six new research-based strategies were taught and analyzed to decide which methods…

  11. Aligning with New Digital Strategy

    DEFF Research Database (Denmark)

    Yeow, Adrian; Soh, Christina; Hansen, Rina

    2018-01-01

    Prior IS research has not fully addressed the aligning process in the highly dynamic context of digital strategy. To address this gap, we conduct a longitudinal analysis of a B2B company's journey to enact its B2C digital strategy, using the dynamic capabilities approach. We found...... that as an organization shifts towards a digital strategy, misalignments between the emergent strategy and resources give rise to tension. Our study resulted in the development of an aligning process model that is comprised of three phases (exploratory, building, and extending) and generalizable organizational aligning...... actions that form the organization's sensing, seizing, and transforming capacities. These aligning actions iteratively reconfigured organizational resources and refined strategy in order to respond to both changes in the environment and internal tensions. We also recognized that there are challenges...

  12. Trophic strategies of unicellular plankton

    DEFF Research Database (Denmark)

    Chakraborty, Subhendu; Nielsen, Lasse Tor; Andersen, Ken Haste

    2017-01-01

    . To this end, we develop and calibrate a trait-based model for unicellular planktonic organisms characterized by four traits: cell size and investments in phototrophy, nutrient uptake, and phagotrophy. We use the model to predict how optimal trophic strategies depend on cell size under various environmental...... unicellulars are colimited by organic carbon and nutrients, and only large photoautotrophs and smaller mixotrophs are nutrient limited; (2) trophic strategy is bottom-up selected by the environment, while optimal size is top-down selected by predation. The focus on cell size and trophic strategies facilitates......Unicellular plankton employ trophic strategies ranging from pure photoautotrophs over mixotrophy to obligate heterotrophs (phagotrophs), with cell sizes from 10-8 to 1 μg C. A full understanding of how trophic strategy and cell size depend on resource environment and predation is lacking...

  13. Abnormal Returns and Contrarian Strategies

    Directory of Open Access Journals (Sweden)

    Ivana Dall'Agnol

    2003-12-01

    Full Text Available We test the hypothesis that strategies which are long on portfolios of looser stocks and short on portfolios of winner stocks generate abnormal returns in Brazil. This type of evidence for the US stock market was interpreted by The Bondt and Thaler (1985 as reflecting systematic evaluation mistakes caused by investors overreaction to news related to the firm performance. We found evidence of contrarian strategies profitability for horizons from 3 months to 3 years in a sample of stock returns from BOVESPA and SOMA from 1986 to 2000. The strategies are more profitable for shorter horizons. Therefore, there was no trace of the momentum effect found by Jagadeesh and Titman (1993 for the same horizons with US data. There are remaing unexplained positive returns for contrarian strategies after accounting for risk, size, and liquidity. We also found that the strategy profitability is reduced after the Real Plan, which suggests that the Brazilian stock market became more efficient after inflation stabilization.

  14. Measurable Strategies in Differential Games

    Science.gov (United States)

    Ivanov, R. P.

    1990-02-01

    Nonlinear approach-evasion differential games are considered in which the initial data depend on the time. These games are investigated in the class of strategies that are functions of three variables, namely, the time, the phase variable, and the current value of the other player's control, and are measurable jointly with respect to the time and the phase variable. The ideas of the Pontryagin methods in differential games and Krasovskiĭ's ideas on extremal aiming are developed, and it is shown that measurable strategies have broad applicability. It is proved that measurable strategies are compatible with differential equations with discontinuous right-hand side, and general theorems on the existence of solving measurable strategies in approach-evasion problems are proved, along with some auxiliary assertions. It is shown that the saddle point condition in the small game ensures the existence of solving measurable strategies. An example is given. Bibliography: 14 titles.

  15. PROMOTION STRATEGIES IN WINE MARKETING

    Directory of Open Access Journals (Sweden)

    Ştefan MATEI

    2014-06-01

    Full Text Available Marketing has proven to be very useful instrument in the wine industry, in fostering comprehensive, cohesive and effective strategies which wineries require to effectively compete in today’s almost saturated wine market. But within wine marketing, the promotion strategy, from our point of view, is the most important component of the winery that can ensure the success in the market or can shorten the life cycle of the product. This being said, the aim of the paper is twofold. Firstly, to determine and analyze the steps that are required to create a promotion strategy in the wine industry, by comparing different approaches. Secondly, to identify the instruments of the promotional mix that helps a winery to implement its promotional strategy. Bearing that in mind, the paper starts with some theoretical aspects regarding the promotion strategy and ends by providing a brief overview of the main findings.

  16. Human capital strategy: talent management.

    Science.gov (United States)

    Nagra, Michael

    2011-01-01

    Large organizations, including the US Army Medical Department and the Army Nurse Corps, are people-based organizations. Consequently, effective and efficient management of the human capital within these organizations is a strategic goal for the leadership. Over time, the Department of Defense has used many different systems and strategies to manage people throughout their service life-cycle. The current system in use is called Human Capital Management. In the near future, the Army's human capital will be managed based on skills, knowledge, and behaviors through various measurement tools. This article elaborates the human capital management strategy within the Army Nurse Corps, which identifies, develops, and implements key talent management strategies under the umbrella of the Corps' human capital goals. The talent management strategy solutions are aligned under the Nurse Corps business strategy captured by the 2008 Army Nurse Corps Campaign Plan, and are implemented within the context of the culture and core values of the organization.

  17. The Relationship Between The Brand Strategy And Business Strategy

    OpenAIRE

    Karaömer, Ahmed

    2013-01-01

    In this study the relationship between three companies brand strategies and business strategies were investigated based on Aaker’s view on brand architecture. The concept and its strategies are characterized by the driving roles brands possess. At the top of the spectrum, “House of Brands” allows the brands to have the entire driver role which decreases moving downwards on the spectrum, first comes “Endorsed Brands” where the master brand has a little driver role, followed by “Subbrands” wher...

  18. Diagnostic Strategy in APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dongyoung; Kim, Jonghyun [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2013-05-15

    These features may bring out changes in operator tasks, changing the characteristics of tasks, or creating new tasks. Diagnostic strategy for identifying anomaly may be different especially in APR1400 from that in the analog control room due to the change of human-system interface, i.e. alarm system and display system. Since the first plant of APR1400 is being built at this moment, it is not known what strategies the operators will adopt in diagnosis tasks in the new operating environment. In this light, this paper aims at investigating operator's diagnostic strategies which are appropriate for APR1400. In order to collect data, several different approaches which are complementary are used to identify diagnostic strategies in the digital control room: analysis on audio/video recording of operation, observation in the simulator, and interview with the operators. The result shows that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of strategies, mostly, by getting more support from the computerized system. This paper investigated how the digitalized control room may influence operator's diagnostic strategies. Several different approaches, i. e., audio/video record, observation of training, and the interview with operators, were used to gather information about the operator's behaviors. As a conclusion, this paper figured out that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of the strategies, mostly, by getting more support from the computerized system. The operators interviewed also commented that the diagnosis in the APR1400 is quicker, more correct, and easier, compared with the analog control room.

  19. Diagnostic Strategy in APR1400

    International Nuclear Information System (INIS)

    Kim, Dongyoung; Kim, Jonghyun

    2013-01-01

    These features may bring out changes in operator tasks, changing the characteristics of tasks, or creating new tasks. Diagnostic strategy for identifying anomaly may be different especially in APR1400 from that in the analog control room due to the change of human-system interface, i.e. alarm system and display system. Since the first plant of APR1400 is being built at this moment, it is not known what strategies the operators will adopt in diagnosis tasks in the new operating environment. In this light, this paper aims at investigating operator's diagnostic strategies which are appropriate for APR1400. In order to collect data, several different approaches which are complementary are used to identify diagnostic strategies in the digital control room: analysis on audio/video recording of operation, observation in the simulator, and interview with the operators. The result shows that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of strategies, mostly, by getting more support from the computerized system. This paper investigated how the digitalized control room may influence operator's diagnostic strategies. Several different approaches, i. e., audio/video record, observation of training, and the interview with operators, were used to gather information about the operator's behaviors. As a conclusion, this paper figured out that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of the strategies, mostly, by getting more support from the computerized system. The operators interviewed also commented that the diagnosis in the APR1400 is quicker, more correct, and easier, compared with the analog control room

  20. Social network marketing strategy and SME strategy benefits

    OpenAIRE

    Nobre, Helena; Silva, Daniela

    2014-01-01

    The study explored what benefits to small or medium-sized firms (SMEs) could be derived from the development of a social media marketing strategy. Results indicated that Facebook can facilitate communications between SME companies and customers, and can also be an important tool in creating brand recognition and broadening awareness. The importance of developing a thoughtfully designed strategy was cited, as SMEs often lack sophisticated marketing or business plans. The positive study results...

  1. The power of strategy metaphors

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang; Holmgren, Jens

    2016-01-01

    and post-structuralism. The paper reports on an action research study of a strategy workshop with the strategic team of a Human Resource Management Department in a Danish Municipality. It identifies two structural dimensions and four generic spatial metaphors were identified. Thus, the paper shows......This paper explores the power of spatial metaphors in strategy making. I seek to unfold a conception of the power of spatial metaphors in strategy making that stresses their creative and critical capacity as well as their constraints on strategic thinking. In order to identify the power of spatial...

  2. Spent nuclear fuel sampling strategy

    International Nuclear Information System (INIS)

    Bergmann, D.W.

    1995-01-01

    This report proposes a strategy for sampling the spent nuclear fuel (SNF) stored in the 105-K Basins (105-K East and 105-K West). This strategy will support decisions concerning the path forward SNF disposition efforts in the following areas: (1) SNF isolation activities such as repackaging/overpacking to a newly constructed staging facility; (2) conditioning processes for fuel stabilization; and (3) interim storage options. This strategy was developed without following the Data Quality Objective (DQO) methodology. It is, however, intended to augment the SNF project DQOS. The SNF sampling is derived by evaluating the current storage condition of the SNF and the factors that effected SNF corrosion/degradation

  3. STRATEGI PENGEMBANGAN ASURANSI TERNAK SAPI

    Directory of Open Access Journals (Sweden)

    Nina Sari An-nisa

    2015-03-01

    Full Text Available Livestock is one of the agricultural Subsectors, which has a strategic role in economic matters in Indonesia. However, livestock faces a lot of risks, which often cause loss for the livestock business agents, especially the breeders. This research aimed to analyze a development strategy on livestock insurance pilot project. The development of the strategy is important for a company in achieving its objectives. This research also aimed to analyze external and internal factors affecting the cattle insurance pilot project implementation and to analyze the company position so that the objectives of the company on cattle insurance pilot project implementation could be determined. Furthermore, this research aimed to design a strategy on the implementation of livestock insurance pilot project, and a case study was used as the research method. The result showed that there were some external and internal factors affecting the development of livestock insurance such as brand image and company performance. The position of the company in the development of livestock insurance is to hold and maintain its position by using the strategic recommendations i.e. market penetration and product development strategy. There are 8 alternative strategies for the development of cow insurance obtained based on the strategy analysis, and there is one suitable alternative strategy obtained by SWOT analysis. The priority strategy obtained in this research by QSPM analysis is given to companies as a recommendation to establish cooperation between companies and the ministry of agriculture to socialize the implementation of livestock insurance and good breeding practice. Keyword: development strategy, cow insurance, pilot project, PT Asuransi Jasa Indonesia, QSPMABSTRAKPeternakan merupakan salah satu subsektor pertanian yang mempunyai peran strategis dalam perekonomian di Indonesia. Namun dalam pelaksanaannya subsektor peternakan menghadapi berbagai risiko yang tidak jarang

  4. Theoretical Aspects of Enterprise Business Strategy Formation

    OpenAIRE

    Valentinavičius, Stasys

    2009-01-01

    The paper presents interpretations of business strategy concept and analyses strategy planning and formation, models. The concept of business strategy is revised and formulated considering various authors approaches. Analysis of business strategy formation process – steps of development and management, selection of strategy type – is based on presented strategy planning models. The aspects of enterprise business and investment strategy formation, coordination and valuation are analysed. The s...

  5. A study on the derivatising condition of 4-methylimidazole using dansyl chloride as pre-column derivatising agent%柱前衍生法测定4-甲基咪唑条件的研究

    Institute of Scientific and Technical Information of China (English)

    王妙飞; 高美珍; 程庚金生; 卑占宇

    2009-01-01

    用丹磺酰氯(Dns-Cl)柱前衍生的高效液相色谱法来测定4-甲基咪唑.研究了衍生试剂的用量、缓冲体系的PH值、衍生时间等条件的变化对衍生反应的影响,得到了用丹磺酰氯对4-甲基咪唑的最佳衍生条件为最佳衍生条件为:加入100倍的丹磺酰氯在pH10.0的溶液中反应40 min.

  6. Study on derivatising condition of biogenic amines with dansyl chloride as pre-column derivatising agent%丹磺酰氯作为生物胺柱前衍生试剂衍生化条件的研究

    Institute of Scientific and Technical Information of China (English)

    董伟峰; 李宪臻; 林维宣

    2005-01-01

    报道了荧光衍生试剂丹磺酰氯同多种生物胺进行衍生化反应条件的实验研究.在丹磺酰氯浓度为9 mg/mL、反应温度为60℃、反应时间为15 min、缓冲体系的pH值为11.5时,衍生效果最佳.衍生试剂和衍生物的稳定性分别可达一个月和半年以上,即可以和伯胺反应又可以和仲胺反应.

  7. STRATEGI PENINGKATAN MUTU PENDIDIKAN ISLAM

    Directory of Open Access Journals (Sweden)

    M. Asep Fathur Rozi

    2016-11-01

    Pengembangan sumberdaya manusia dipengaruhi kualitas lembaga pendidikan. Kualitas lembaga pendidikan dipengaruhi oleh visi dan misi lembaga tersebut. Perumusan visi dan misi lembaga melibatkan stakeholder yang sudah di tentukan oleh lembaga. Faktor yang meny ebabkan mutu pendidikan kurang berhasil antara lain, strategi pendidikan yang bersifat input oriented dan pengelolaan pendidikan selama ini lebih bersifat macro-oriented. Setelah penyusunan visi dan misi, lembaga merumuskan rencana strategis. Strategi merupakan kebijakan penting dari lembaga sebagai patokan dalam pembuatan program kelembagaan. Usaha yang bisa dilakukan oleh lembaga pendidikan untuk meningkatkan mutu institusi, antara lain: menyiapkan pemimpin yang berkualitas, merumuskan visi dan misi dengan ciri khas yang hanya dimiliki oleh intitusi, merumuskan strategi dalam rangka mewujudkan tujuan institusi, meningkatkan kemampuan sumberdaya manusia, melakukan survei pasar, melengkapi sarana dan prasarana, manajemen keuangan, menjalin kerjasama dengan stakeholder, merawat konsistensi mutu.

  8. Industrial strategy for nondestructive control

    International Nuclear Information System (INIS)

    Martin, P.; Michaut, J.P.

    1994-01-01

    For Electricite de France, the nondestructive control strategy passes by a responsibility of services, a competition between companies, a clarification of the market access and a dialogue with the companies

  9. Voyager 2 Uranus targeting strategy

    Science.gov (United States)

    Cesarone, R. J.; Gray, D. L.; Potts, C. L.; Francis, K.

    1986-01-01

    One of the major challenges involved in the Voyager 2 Uranus flyby is to deliver the spacecraft to an appropriate aimpoint at the optimum time, so as to maximize the science return of the mission, while yet keeping propellant expenditure low. An unusual targeting strategy has been devised to satisfy these requirements. Its complexity arises from the great distance of the planet Uranus and the limited performance capabilities of Voyager. This selected strategy is developed in relation to a set of candidate strategies, mission requirements and shifting science objectives. The analysis of these candidates is conducted via a Monte Carlo simulation, the results of which yield data for the comparative evaluation and eventual and selection of the actual targeting strategy to be employed.

  10. Strategy against hazardous environmental events

    International Nuclear Information System (INIS)

    Estefan, S.F.

    1992-01-01

    The major sources of waterways pollution in egypt have been assessed compact strategy is committed to promote sustainable development of our natural resources and to secure the safety of our environmental capital

  11. Environmental Economics Research Strategy (2005)

    Science.gov (United States)

    This 2005 Environmental Economics Research Strategy outlines EPA’s research effort to provide the necessary behavioral science foundation for making decisions and designing environmental policies at the least cost to American businesses and consumers.

  12. Strategies for Mentoring Pedagogical Knowledge

    Science.gov (United States)

    Hudson, Peter

    2013-01-01

    Fundamental for mentoring a preservice teacher is the mentor's articulation of pedagogical knowledge, which in this research draws upon specific practices, viz.: planning, timetabling lessons, preparation, teaching strategies, content knowledge, problem solving, questioning, classroom management, implementation, assessment and viewpoints for…

  13. 2007 National Money Laundering Strategy

    National Research Council Canada - National Science Library

    2007-01-01

    ... them. The National Money Laundering Strategy for 2007 identifies areas in which the U.S. government will work to revise, enhance, or renew efforts to enforce existing Federal laws and regulations...

  14. Strategies for online test security.

    Science.gov (United States)

    Hart, Leigh; Morgan, Lesley

    2009-01-01

    As online courses continue to increase, maintaining academic integrity in student evaluation is a challenge. The authors review several strategies, with varying degrees of cost and technology, to improve test security in the online classroom.

  15. Competitive Strategy in Continuing Education.

    Science.gov (United States)

    Baden, Clifford

    1987-01-01

    Reviews strategic variables available to those planning continuing education marketing programs. Discusses generic competitive strategies: (1) overall cost leadership, (2) differentiation, and (3) specialization. Mentions several potential problems. (CH)

  16. Strategies for healthcare information systems

    NARCIS (Netherlands)

    Stegwee, R.A.; Spil, Antonius A.M.

    2001-01-01

    Information technologies of the past two decades have created significant fundamental changes in the delivery of healthcare services by healthcare provider organizations. Many healthcare organizations have been in search of ways and strategies to keep up with continuously emerging information

  17. United States Strategy for Mexico

    National Research Council Canada - National Science Library

    Centner, Robert C

    2005-01-01

    The security and stability of Mexico is of national interest to the United States, and a strong, effective alliance between the two countries is pivotal to our national defense strategy and economic prosperity...

  18. Military Strategy of Global Jihad

    National Research Council Canada - National Science Library

    Zabel, Sarah E

    2007-01-01

    .... The 9/11 attacks set this plan in motion. In the years leading up to and following the 9/11 attacks, global jihadis have written copiously on their military strategy for creating an Islamic state...

  19. Strategy: A Philosophy of Doctrine.

    Science.gov (United States)

    1983-06-01

    Strategy is a complex subject. It has no answers; only- informed opinion and judgment, based on a study of history. In an era of positivism ...materialism, and quantitative analy- sis, such indeterminacy is discomforting. Yet, because of the uncertain environment of strategy, planners and decision...has been applied. One such fault is the ability to "lie" with statistics, which largely defeats the purpose of rigorous quantitative analysis

  20. Can NATO Practice Grand Strategy?

    DEFF Research Database (Denmark)

    Barfoed, Jacob

    2014-01-01

    In its intervention in Libya, not only did NATO fail to produce a military strategy and a campaign plan before commencing military operations, what is more worrisome was the lack of political guidance to and control of the Joint Task Force.......In its intervention in Libya, not only did NATO fail to produce a military strategy and a campaign plan before commencing military operations, what is more worrisome was the lack of political guidance to and control of the Joint Task Force....

  1. Marketingová strategie penzionu

    OpenAIRE

    Fišerová, Markéta

    2015-01-01

    This bachelor thesis deals with suggestion of marketing strategy for particular business subject. First part concentrates on marketing strategy, marketing of services, marketing mix and tourism together with accommodation sector. In the second part of thesis is effected description of the pension and its marketing mix, internal and external analysis and resulting SWOT analysis. Marketing research is another source for creation suggestion. Final part summarises all pieces of knowledge and pres...

  2. Switching strategies to optimize search

    International Nuclear Information System (INIS)

    Shlesinger, Michael F

    2016-01-01

    Search strategies are explored when the search time is fixed, success is probabilistic and the estimate for success can diminish with time if there is not a successful result. Under the time constraint the problem is to find the optimal time to switch a search strategy or search location. Several variables are taken into account, including cost, gain, rate of success if a target is present and the probability that a target is present. (paper: interdisciplinary statistical mechanics)

  3. Organizational strategy, structure, and process.

    Science.gov (United States)

    Miles, R E; Snow, C C; Meyer, A D; Coleman, H J

    1978-07-01

    Organizational adaptation is a topic that has received only limited and fragmented theoretical treatment. Any attempt to examine organizational adaptation is difficult, since the process is highly complex and changeable. The proposed theoretical framework deals with alternative ways in which organizations define their product-market domains (strategy) and construct mechanisms (structures and processes) to pursue these strategies. The framework is based on interpretation of existing literature and continuing studies in four industries (college textbook publishing, electronics, food processing, and health care).

  4. Recycling - Danish Waste Management Strategy

    DEFF Research Database (Denmark)

    Romann, Anne Funch; Thøgersen, John; Husmer, Lis

    The report challanges recycling as the only waste handling strategy. The tonnes of recycled materials should not be the only goal - it is essential to minimize the waste production and focus on eliminating hazardous materials.......The report challanges recycling as the only waste handling strategy. The tonnes of recycled materials should not be the only goal - it is essential to minimize the waste production and focus on eliminating hazardous materials....

  5. Evaluation strategies in CT scanning

    DEFF Research Database (Denmark)

    In this talk, dimensional measurement results using different measuring strategies applied in different inspection software packages for volume and surface data analysis are presented. The influence of the strategy on the dimensional measurement is determined by calculating the measurement...... uncertainty. This investigation includes measurements of two industrial items, an aluminum pipe connector and a plastic toggle, a hearing aid component. These are measured using a commercial CT scanner. Traceability is transferred using tactile and optical coordinate measuring machines, which are used...

  6. Strategi Komunikasi Membangun Kemandirian Pangan

    OpenAIRE

    Rangkuti, Parlaungan Adil

    2009-01-01

    Communication strategy in developing food independencyRole of agricultural development communication is important to build food self-suffiency and diversification as the main base of food independency and food security. Food independency will be accomplished if its development comes from people initiative as an awareness to build modern farm industry with effective and efficient communication strategy support. Adoption of innovation technology by means of communication will boost productivity...

  7. Vietnam; Poverty Reduction Strategy Paper

    OpenAIRE

    International Monetary Fund

    2004-01-01

    This paper assesses the Poverty Reduction Strategy Paper of Vietnam, known as the Comprehensive Poverty Reduction and Growth Strategy (CPRGS). It is an action program to achieve economic growth and poverty reduction objectives. This paper reviews the objectives and tasks of socio-economic development and poverty reduction. The government of Vietnam takes poverty reduction as a cutting-through objective in the process of country socio-economic development and declares its commitment to impleme...

  8. Tax planning strategies for physicians.

    Science.gov (United States)

    Pope, Thomas R; Schwartz, Richard W

    2002-07-01

    The development of tax reduction strategies is a critical aspect of both corporate and personal financial planning because taxes represent the largest annual expenditure for the majority of Americans. The categories of tax reduction strategies discussed include charitable-giving techniques, ways to maximize business deductions, shifting income to family members, education tax incentives, retirement planning, and small business tax considerations. One use for these tax savings is the enhancement of a corporation's capabilities to provide services to patients.

  9. Optimal Strategy and Business Models

    DEFF Research Database (Denmark)

    Johnson, Peter; Foss, Nicolai Juul

    2016-01-01

    This study picks up on earlier suggestions that control theory may further the study of strategy. Strategy can be formally interpreted as an idealized path optimizing heterogeneous resource deployment to produce maximum financial gain. Using standard matrix methods to describe the firm Hamiltonia...... variable of firm path, suggesting in turn that the firm's business model is the codification of the application of investment resources used to control the strategic path of value realization....

  10. Strategi Public Relations Pariwisata Bali

    OpenAIRE

    Cahaya Putra, Kadek Dwi

    2008-01-01

    Abstract: Bali has to maintain its image and reputation as the world leading class tourist destination. Tourism in fact is a vulnerable industry easily ruined by related issues and crises. Therefore, Public Relations (PR) with its communication strategy is highly required to maintain good relationships with related parties. This study is aimed at identifying Bali’s Public Relations positioning and setting up its PR strategies. Data and information are gained by means of questionnaire distri...

  11. Trends in Corporate Communication Strategies

    OpenAIRE

    Constantin Milosteanu; Ionel Scaunasu; Alina Cornescu; Nicolae Popovic

    2011-01-01

    When business strategy is correlated with corporate communication strategy, this is reflected in the position and image of the organization on the market, leading to higher sales and increased profitability. The major changes caused by globalization, coupled with the new dynamic of the markets where consumers have access to more information in less time, require new forms of corporate communication. The new corporate communication concept involves major challenges for managers and can help de...

  12. Military Strategy vs. Military Doctrine

    DEFF Research Database (Denmark)

    Barfoed, Jacob

    2015-01-01

    The article argues that while doctrine represents the more scientific side of warfare, strategy represents the artistic side. Existing doctrine will almost never meet the requirements for winning the next war; it is through the artistic application of generic peacetime doctrine to the specific st...... strategic and operational context, using doctrine as building blocks for a context specific military strategy, that the military commander outwits and defeats or coerces the adversary and achieves the military objectives....

  13. Putting leadership back into strategy.

    Science.gov (United States)

    Montgomery, Cynthia A

    2008-01-01

    In recent decades an infusion of economics has lent the study of strategy much needed theory and empirical evidence. Strategy consultants, armed with frameworks and techniques, have stepped forward to help managers analyze their industries and position their companies for strategic advantage. Strategy has come to be seen as an analytical problem to be solved. But, says Montgomery, the Timken Professor of Business Administration at Harvard Business School, the benefits of this rigorous approach have attendant costs: Strategy has become a competitive game plan, separate from the company's larger sense of purpose. The CEO's unique role as arbiter and steward of strategy has been eclipsed. And an overemphasis on sustainable competitive advantage has obscured the importance of making strategy a dynamic tool for guiding the company's development over time. For any company, intelligent guidance requires a clear sense of purpose, of what makes the organization truly distinctive. Purpose, Montgomery says, serves as both a constraint on activity and a guide to behavior. Creativity and insight are key to forging a compelling organizational purpose; analysis alone will never suffice. As the CEO--properly a company's chief strategist--translates purpose into practice, he or she must remain open to the possibility that the purpose itself may need to change. Lou Gerstner did this in the 1990s, when he decided that IBM would evolve to focus on applying technology rather than on inventing it. So did Steve Jobs, when he rescued Apple from a poorly performing strategy and expanded the company into attractive new businesses. Watching over strategy day in and day out is the CEO's greatest opportunity to shape the firm as well as outwit the competition.

  14. PROMOTION STRATEGIES IN WINE MARKETING

    OpenAIRE

    Ştefan MATEI

    2014-01-01

    Marketing has proven to be very useful instrument in the wine industry, in fostering comprehensive, cohesive and effective strategies which wineries require to effectively compete in today’s almost saturated wine market. But within wine marketing, the promotion strategy, from our point of view, is the most important component of the winery that can ensure the success in the market or can shorten the life cycle of the product. This being said, the aim of the paper is twofold. Firstly, to deter...

  15. Marketing strategies for academic libraries

    OpenAIRE

    Jung, Claudia

    2008-01-01

    This assignment is about the development of a general strategic marketing plan for academic libraries in Germany and can be used as a guideline for libraries that want to develop concrete marketing strategies for several products and services. Two examples of marketing projects are at its end presented for linking theoretical approaches to practice. Finally the development of an own marketing strategy for “information literacy” builds the last part of the assignment.

  16. Department of Energy licensing strategy

    International Nuclear Information System (INIS)

    Frei, M.W.

    1984-01-01

    The Department of Energy (DOE) is authorized by the Nuclear Waste Policy Act of 1982 (Act) to site, design, construct, and operate mined geologic repositories for high-level radioactive wastes and is required to obtain licenses from the Nuclear Regulatory Commission (NRC) to achieve that mandate. To this end the DOE has developed a licensing approach which defines program strategies and which will facilitate and ease the licensing process. This paper will discuss the regulatory framework within which the repository program is conducted, the DOE licensing strategy, and the interactions between DOE and NRC in implementing the strategy. A licensing strategy is made necessary by the unique technical nature of the repository. Such a facility has never before been licensed; furthermore, the duration of isolation of waste demanded by the proposed EPA standard will require a degree of reliance on probabilistic performance assessment as proof of compliance that is a first of a kind for any industry. The licensing strategy is also made necessary by the complex interrelationships among the many involved governmental agencies and even within DOE itself, and because these relationships will change with time. Program activities which recognize these relationships are essential for implementing the Act. The guiding principle in this strategy is an overriding commitment to safeguarding public health and safety and to protecting the environment

  17. Strategy for future seabed investigations

    International Nuclear Information System (INIS)

    Richards, A.F.; Murray, C.N.

    1989-01-01

    The status of seabed disposal studies and possible strategies for future development are reviewed. Background information for strategy development includes presentation of selected recommendations for future studies identified by the NEA/OECD Seabed Working Group, the Engineering Studies Task Group of the Seabed Working Group and the Subseabed Consortium. Inferences from these recommendations, and how sound scientifically based research, significant political perception and technological proof of concept may be related to strategies are considered as a prelude to strategy design. A proposed European strategy, complementary to the 1988 Subseabed Consortium strategy developed in the US, is to proceed to the technological proof of concept by emplacing one or more full-sized waste canisters containing non-radioactive, simulated heat-producing waste by a chosen deployment system. The latter could include the drilled, the penetrator or the pushed-in option. Emplaced canisters would be monitored for an extended period of time, and eventually retrieved for examination. International co-operation and co-ordination of all aspects is recommended. (author)

  18. Communication Strategies in the Written Medium

    Science.gov (United States)

    Xhaferi, Brikena

    2012-01-01

    The field of second language acquisition has distinguished between two types of strategies: learning strategies and communication strategies. Learning strategies deal with the receptive domain of intake, memory, storage, and recall. Communication strategies pertain to the employment of verbal and nonverbal mechanisms for the productive…

  19. A comparison of fast and reactive pyrolysis with insitu derivatisation of fructose, inulin and Jerusalem artichoke (Helianthus tuberosus).

    Science.gov (United States)

    Mattonai, Marco; Ribechini, Erika

    2018-08-09

    Reactive pyrolysis is a technique that provides mechanistic information by performing pyrolysis of the substrate in a sealed glass capsule at elevated temperature and pressure for relatively long time. This technique has already shown great potential for the analysis of biomass, favouring the formation of only the most thermostable compounds. In this work, both fast and reactive pyrolysis with on-line gas chromatography-mass spectrometry analysis (Py-GC/MS) are used to study fructose, inulin and Jerusalem artichoke tubers (Heliantus tuberosus). Interesting differences were found between the two systems, and became even more evident as the reaction time was increased. The most striking result was the formation of di-fructose dianhydrides (DFAs), a class of compounds with interesting biological activities. DFAs were obtained in high yields from reactive pyrolysis, but not from fast pyrolysis. Hypotheses on the pyrolysis mechanisms were made based upon the composition of the pyrolysates. This work describes for the first time the behaviour of fructans under reactive pyrolysis. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. Waste Management Strategy in The Netherlands. Part 3. Strategy Selection

    International Nuclear Information System (INIS)

    Haverkate, B.R.W.

    2003-01-01

    This report reflects the Dutch input prepared in the framework of work package 3 of the EU thematic network COMPAS, which dealt with the evaluation and comparison of waste management strategies in EU member states and their applicant countries. Based on three generic decision trees the current strategy as well as the reason(s) for the selected options regarding radioactive waste management in The Netherlands is extensively described in this report. The trees are represented in terms of (numbered) decision nodes. Each node is discussed in the context of the Dutch situation, with relevant potential outcomes being highlighted where possible. After a short introduction (chapter 1) followed by a brief waste management policy overview (chapter 2), this approach is considered, in chapter 3, for: spent nuclear fuel and high level waste; low and intermediate level waste; disposal strategy

  1. From the Lisbon Strategy to EUROPE 2020

    DEFF Research Database (Denmark)

    Lundvall, Bengt-Åke; Lorenz, Edward

    2011-01-01

    This article compares the Lisbon Strategy and the EUROPE 2020 Strategy. It demonstrates while none of the two strategies are sufficient as support for the monetary integration and the Euro-collaboration....

  2. Strategy Of Translating Gadget Brochure

    Directory of Open Access Journals (Sweden)

    Deny Kusuma

    2015-10-01

    Full Text Available The title of this writing is strategy of translating gadget brochure. There were two problems discussed in this thesis, namely (1 terms found in the gadget manual book and its equivalence in Indonesia, (2 strategies applied in translating gadget brochure. Based on the analysis result, it was found that the terms and its equivalent words found in the gadget brochure were classified based on: 1 simple words or compound words and terminology forming phrase. 2 words category found are: noun and verb. The recommended pattern to determine the equivalent word was pure borrowing strategy, not adaptation borrowing strategy. The adaptation borrowing in this context was related to the spellings, the pronunciation or sound adaptation in the TL rather than adaptation for the cultural substitutes that conceptually mismatches with the standardized terminology in the SL. In addition, the result of the analysis that there were seven strategies found in gadget brochure, they were translation by more general word (Superordinate, translation by a more neutral/expressive word, translation by cultural substitution, translation by using loan word or loan word plus explanation, translation by paraphrase using related word, translation by omission and translation by illustration.

  3. BWR control blade replacement strategies

    Energy Technology Data Exchange (ETDEWEB)

    Kennard, M W [Stoller Nuclear Fuel, NAC International, Pleasantville, NY (United States); Harbottle, J E [Stoller Nuclear Fuel, NAC International, Thornbury, Bristol (United Kingdom)

    2000-02-01

    The reactivity control elements in a BWR, the control blades, perform three significant functions: provide shutdown margin during normal and accident operating conditions; provide overall core reactivity control; and provide axial power shaping control. As such, the blades are exposed to the core's neutron flux, resulting in irradiation of blade structural and absorber materials. Since the absorber depletes with time (if B{sub 4}C is used, it also swells) and the structural components undergo various degradation mechanisms (e.g., embrittlement, corrosion), the blades have limits on their operational lifetimes. Consequently, BWR utilities have implemented strategies that aim to maximize blade lifetimes while balancing operational costs, such as extending a refuelling outage to shuffle high exposure blades. This paper examines the blade replacement strategies used by BWR utilities operating in US, Europe and Asia by assembling information related to: the utility's specific blade replacement strategy; the impact the newer blade designs and changes in core operating mode were having on those strategies; the mechanical and nuclear limits that determined those strategies; the methods employed to ensure that lifetime limits were not exceeded during operation; and blade designs used (current and replacement blades). (author)

  4. BWR control blade replacement strategies

    International Nuclear Information System (INIS)

    Kennard, M.W.; Harbottle, J.E.

    2000-01-01

    The reactivity control elements in a BWR, the control blades, perform three significant functions: provide shutdown margin during normal and accident operating conditions; provide overall core reactivity control; and provide axial power shaping control. As such, the blades are exposed to the core's neutron flux, resulting in irradiation of blade structural and absorber materials. Since the absorber depletes with time (if B 4 C is used, it also swells) and the structural components undergo various degradation mechanisms (e.g., embrittlement, corrosion), the blades have limits on their operational lifetimes. Consequently, BWR utilities have implemented strategies that aim to maximize blade lifetimes while balancing operational costs, such as extending a refuelling outage to shuffle high exposure blades. This paper examines the blade replacement strategies used by BWR utilities operating in US, Europe and Asia by assembling information related to: the utility's specific blade replacement strategy; the impact the newer blade designs and changes in core operating mode were having on those strategies; the mechanical and nuclear limits that determined those strategies; the methods employed to ensure that lifetime limits were not exceeded during operation; and blade designs used (current and replacement blades). (author)

  5. Marketing Strategy of a Company

    OpenAIRE

    Koukalová, Barbora

    2010-01-01

    Předmětem mé diplomové práce „Návrh marketingové strategie pro firmu“ je analyzování marketingové strategie firmy Bábor Eurodance a návrh marketingové strategie na příští období. První část tvoří kapitoly, ve kterých jsou zachyceny různá teoretická východiska marketingu a postup tvorby marketingové strategie. Druhá část je zaměřena na podnik Bábor Eurodance, konkrétně na jeho současnou marketingovou strategii a vytvoření podkladů pro návrh nové marketingové strategie a třetí část obsahuje sam...

  6. A belief-based evolutionarily stable strategy

    OpenAIRE

    Deng, Xinyang; Wang, Zhen; Liu, Qi; Deng, Yong; Mahadevan, Sankaran

    2014-01-01

    As an equilibrium refinement of the Nash equilibrium, evolutionarily stable strategy (ESS) is a key concept in evolutionary game theory and has attracted growing interest. An ESS can be either a pure strategy or a mixed strategy. Even though the randomness is allowed in mixed strategy, the selection probability of pure strategy in a mixed strategy may fluctuate due to the impact of many factors. The fluctuation can lead to more uncertainty. In this paper, such uncertainty involved in mixed st...

  7. Naesliden project: FEM modelling strategies

    Energy Technology Data Exchange (ETDEWEB)

    Borg, T.

    1980-05-15

    A schematized description is given of the different stages in the project. The aim is to show the development of the project and the strategies which have been chosen. The four different stages in the project are treated from the following points of view: the reasons for the choice of material models; the determination of model properties; and the control of the calculated values. In the origin plan for the project it was stated to only use a joint element model. However, it was shown to be a reasonable strategy to use both a general linear elastic model and a geometric restricted model with joint elements. During the course of the Project's development stages, it was found that a reduction in the number of rock types could be made without loss of generality. A modified strategy is suggested based on more studies of the rock bahavior and less advanced calculations in the first stages of the project.

  8. Schroedinger operators and evolutionary strategies

    International Nuclear Information System (INIS)

    Asselmeyer, T.

    1997-01-01

    First we introduce a simple model for the description of evolutionary algorithms, which is based on 2nd order partial differential equations for the distribution function of the individuals. Then we turn to the properties of Boltzmann's and Darwin's strategy. the next chapter is dedicated to the mathematical properties of Schroedinger operators. Both statements on the spectral density and their reproducibility during the simulation are summarized. The remaining of this chapter are dedicated to the analysis of the kernel as well as the dependence of the Schroedinger operator on the potential. As conclusion from the results of this chapter we obtain the classification of the strategies in dependence of the fitness. We obtain the classification of the evolutionary strategies, which are described by a 2nd order partial differential equation, in relation to their solution behaviour. Thereafter we are employed with the variation of the mutation distribution

  9. Voyager 2 Neptune targeting strategy

    Science.gov (United States)

    Potts, C. L.; Francis, K.; Matousek, S. E.; Cesarone, R. J.; Gray, D. L.

    1989-01-01

    The success of the Voyager 2 flybys of Neptune and Triton depends upon the ability to correct the spacecraft's trajectory. Accurate spacecraft delivery to the desired encounter conditions will promote the maximum science return. However, Neptune's great distance causes large a priori uncertainties in Neptune and Triton ephemerides and planetary system parameters. Consequently, the 'ideal' trajectory is unknown beforehand. The targeting challenge is to utilize the gradually improving knowledge as the spacecraft approaches Neptune to meet the science objectives, but with an overriding concern for spacecraft safety and a desire to limit propellant expenditure. A unique targeting strategy has been developed in response to this challenge. Through the use of a Monte Carlo simulation, candidate strategies are evaluated by the degree to which they meet these objectives and are compared against each other in determining the targeting strategy to be adopted.

  10. OPEC's strategies

    Energy Technology Data Exchange (ETDEWEB)

    Wirl, Franz [Vienna Univ. (Austria). Faculty of Business, Economics and Statistics

    2012-09-15

    This paper investigates rationale explanations of OPEC's strategies. Accounting for market characteristics in particular the sluggishness of demand and supply allows to explain price jumps as rational OPEC strategies from a narrow economic perspective (up and down) as well as from political objectives (at least up) due to the political payoff from standing up against the 'West'. Although the temptation to accrue this political payoff was and remains high, the narrow economic profit motive coupled with an imperfect cooperation among OPEC members explains past price volatility and high prices much better than the usual reference to political events. A more specific prediction is that OPEC will switch back to setting prices since the current quantity strategy encourages oil importing countries to appropriate rents in particular in connection with the need to mitigate global warming. (orig.)

  11. Alan Greenspan, the confidence strategy

    Directory of Open Access Journals (Sweden)

    Edwin Le Heron

    2006-12-01

    Full Text Available To evaluate the Greenspan era, we nevertheless need to address three questions: Is his success due to talent or just luck? Does he have a system of monetary policy or is he himself the system? What will be his legacy? Greenspan was certainly lucky, but he was also clairvoyant. Above all, he has developed a profoundly original monetary policy. His confidence strategy is clearly opposed to the credibility strategy developed in central banks and the academic milieu after 1980, but also inflation targeting, which today constitutes the mainstream monetary policy regime. The question of his legacy seems more nuanced. However, Greenspan will remain 'for a considerable period of time' a highly heterodox and original central banker. His political vision, his perception of an uncertain world, his pragmatism and his openness form the structure of a powerful alternative system, the confidence strategy, which will leave its mark on the history of monetary policy.

  12. Classical and quantum fingerprinting strategies

    International Nuclear Information System (INIS)

    Scott, A.; Walgate, J.; Sanders, B.

    2005-01-01

    Full text: Fingerprinting enables two parties to infer whether the messages they hold are the same or different when the cost of communication is high: each message is associated with a smaller fingerprint and comparisons between messages are made in terms of their fingerprints alone. When the two parties are forbidden access to a public coin, it is known that fingerprints composed of quantum information can be made exponentially smaller than those composed of classical information. We present specific constructions of classical fingerprinting strategies through the use of constant-weight codes and provide bounds on the worst-case error probability with the help of extremal set theory. These classical strategies are easily outperformed by quantum strategies constructed from line packings and equiangular tight frames. (author)

  13. Strategi Periklanan pada Bisnis Retail

    Directory of Open Access Journals (Sweden)

    Veny Ari Sejati

    2015-01-01

    Full Text Available This research aims to analyze the benefits of advertising strategy of Poundland. The method used is a qualitative approach because its ability to produce an in-depth description to obtain an authentic understanding of the experience of the people concerned. The study found that Poundland conducted intensive advertising by utilizing important moments such as Halloween, Christmas, Mother Day, etc using Internet media, social media, and e-mail sent 1-2 times per week. Poundland also employs other media such as word of mouth spread among students. Catalog is also used as the print media to reach the consumers. Poundland uses communication technology and take advantage of important moments for advertising strategy. This description can be a reference for retail businesses in Indonesia to pay attention to important events in Indonesia such as national moments and utilizing non-traditional communication technologies as an advertising strategy.

  14. The Media Strategy Game : Fostering Discussion on Media Strategy

    NARCIS (Netherlands)

    Dr. H.M.M. van Vliet; Rogier Brussee; Jeroen Nobel; Charlotte van Nus

    2013-01-01

    All social media should have a sticker saying 'Don't Jump for the Tool!' While it is tempting 'to use Twitter', the choice of a medium like Twitter cannot be seen in isolation of strategic goals, instruments and expected results, i.e. a communication strategy. We designed a board game, called the

  15. Spacepower for Australias Security - Grand Strategy or Strategy of Grandeur

    Science.gov (United States)

    2012-06-01

    2000), 34–35; Also see Peter H Diamandis and Steven Kotler , Abundance: The Future Is Better Than You Think (New York: Free Press, 2012... Kotler . Abundance: The Future Is Better Than You Think. New York: Free Press, 2012. DOD. “National Security Space Strategy -Unclassified Summary

  16. Inertia in strategy switching transforms the strategy evolution.

    Science.gov (United States)

    Zhang, Yanling; Fu, Feng; Wu, Te; Xie, Guangming; Wang, Long

    2011-12-01

    A recent experimental study [Traulsen et al., Proc. Natl. Acad. Sci. 107, 2962 (2010)] shows that human strategy updating involves both direct payoff comparison and the cost of switching strategy, which is equivalent to inertia. However, it remains largely unclear how such a predisposed inertia affects 2 × 2 games in a well-mixed population of finite size. To address this issue, the "inertia bonus" (strategy switching cost) is added to the learner payoff in the Fermi process. We find how inertia quantitatively shapes the stationary distribution and that stochastic stability under inertia exhibits three regimes, with each covering seven regions in the plane spanned by two inertia parameters. We also obtain the extended "1/3" rule with inertia and the speed criterion with inertia; these two findings hold for a population above two. We illustrate the above results in the framework of the Prisoner's Dilemma game. As inertia varies, two intriguing stationary distributions emerge: the probability of coexistence state is maximized, or those of two full states are simultaneously peaked. Our results may provide useful insights into how the inertia of changing status quo acts on the strategy evolution and, in particular, the evolution of cooperation.

  17. Security Problems of Communicative Strategies

    Directory of Open Access Journals (Sweden)

    Elena B. Perelygina

    2011-01-01

    Full Text Available The main directions of safety formation in communication strategies are connected with their adaptation to the conditions of social and psychological variability. Building up a communicative strategy is a versatile process, in which it is necessary to consider a wide spectrum of social and psychological parameters, especially topical in the modern period of social development. Forms of social interactions in schematic formats of contemporary social and economic revolution are reduced, social and functional potentials are depleted, mass society is further differentiating, the pace of historic changes is growing, all this determines the necessity to prepare changes in personality structures to the dynamics of social and fluidity.

  18. Nuclear fuel reprocessing expansion strategies

    International Nuclear Information System (INIS)

    Gallagher, J.M.

    1975-01-01

    A description is given of an effort to apply the techniques of operations research and energy system modeling to the problem of determination of cost-effective strategies for capacity expansion of the domestic nuclear fuel reprocessing industry for the 1975 to 2000 time period. The research also determines cost disadvantages associated with alternative strategies that may be attractive for political, social, or ecological reasons. The sensitivity of results to changes in cost assumptions was investigated at some length. Reactor fuel types covered by the analysis include the Light Water Reactor (LWR), High-Temperature Gas-Cooled Reactor (HTGR), and the Fast Breeder Reactor (FBR)

  19. CONCEAL TO SURVIVE: RESISTANCE STRATEGIES

    Directory of Open Access Journals (Sweden)

    Francisca Zuleide Duarte de Souza

    2013-04-01

    Full Text Available This paper analyzes the strategy of concealment, theoretically bounded by Accetto (2001, and used by Delfina, character in the novel O Alegre Canto da Perdiz of Paulina Chiziane, Mozambican writer. Focuses, among other things, the relationship colonizer versus colonized, discussing the con­dition of female inferiority that forces a reaction apparently submissive, which assumes the sale of the body and the rejection of their ancestral tra­ditions. To interpret the attitudes of Delfina as a strategy that masks resent­ment against abusive domain power.

  20. Energy strategies for the UK

    International Nuclear Information System (INIS)

    Littlechild, S.C.; Vaidya, K.G.

    1982-01-01

    This book provides the first comprehensive and integrated model of the UK energy sector which focuses on decision-making and optimisation rather than on forecasting or simulation. It incorporates the production and investment policy of all the major fuels (coal, oil, gas and electricity) over a fifty year horizon and analyses strategy under a variety of different assumptions about costs, demands, technolgy and future decisions. The authors cover the wide spectrum of energy problems and policy, including scenarios of rising il and gas prices, and there are striking calculations of the (low) costs of a non-nuclear plus conservation strategy. (author)

  1. Voyager 1 Saturn targeting strategy

    Science.gov (United States)

    Cesarone, R. J.

    1980-01-01

    A trajectory targeting strategy for the Voyager 1 Saturn encounter has been designed to accomodate predicted uncertainties in Titan's ephemeris while maximizing spacecraft safety and science return. The encounter is characterized by a close Titan flyby 18 hours prior to Saturn periapse. Retargeting of the nominal trajectory to account for late updates in Titan's estimated position can disperse the ascending node location, which is nominally situated at a radius of low expected particle density in Saturn's ring plane. The strategy utilizes a floating Titan impact vector magnitude to minimize this dispersion. Encounter trajectory characteristics and optimal tradeoffs are presented.

  2. Maintenance as a corporate strategy.

    Science.gov (United States)

    Clarke, D

    2000-11-01

    As we move towards the 21st century, those Manufacturing Industries that survive, will have changed their "efficiency" focus away from the conventional wisdom of "efficient individual tasks", to focus on the "effectiveness of a total manufacturing process". This seemingly insignificant change of emphasis, (from task to process) must include "the integration of process plant maintenance into the production process". Manufacturing companies, which do not include an effective plant maintenance strategy into their business strategy, will not survive the business environment of the 21st Century.

  3. Strategy, culture and innovation performance

    DEFF Research Database (Denmark)

    do Nascimento Gambi, Lillian; Boer, Harry

    2015-01-01

    Firms strive for improving their performance, and organizational culture has been recognized as an important driver of better performance. In parallel, strategy is viewed as an important contextual variable that influences organizational culture as well as performance. This study has two main goals......: (1) investigating the relationship between strategic practices and innovation performance, and (2) determining if strategy has a direct and/or an indirect, culture-mediated effect on innovation performance, and if this effect varies across strategic practices and culture profiles. The research model...... cultural profile achieve the strongest performance effects....

  4. Effective strategies for behavior change.

    Science.gov (United States)

    Coleman, Mary Thoesen; Pasternak, Ryan H

    2012-06-01

    Strategies that are most effective in both prevention and management of chronic disease consider factors such as age, ethnicity, community, and technology. Most behavioral change strategies derive their components from application of the health belief model, the theory of reasoned action/theory of planned behavior, transtheoretical model, and social cognitive theory. Many tools such as the readiness ruler and personalized action plan form are available to assist health care teams to facilitate healthy behavior change. Primary care providers can support behavior changes by providing venues for peer interventions and family meetings and by making new partnerships with community organizations. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Immunotherapeutic strategies in antiphospholipid syndrome.

    Science.gov (United States)

    Hoi, A Y; Ross, L; Day, J; Buchanan, R R C

    2017-03-01

    Antiphospholipid syndrome is an autoimmune condition, characterised by the persistent presence of antiphospholipid antibodies and either thrombosis or obstetric morbidity. The cornerstone of therapy is long-term anticoagulation to reduce morbidity and mortality; however, better understanding of the immunological pathways may direct us to develop future therapeutic strategies. We provide an overview of the current understanding of the immunopathogenesis of this perplexing condition and its associated morbidities and current evidence for some of the immunotherapeutic strategies. © 2017 Royal Australasian College of Physicians.

  6. CULTURAL ENTREPRENEURSHIP STRATEGIES IN IRAN

    Directory of Open Access Journals (Sweden)

    Fateme Tohidy Ardahaey

    2010-11-01

    Full Text Available This article initially deals with the concepts of entrepreneurship, cultural entrepreneurship and its importance in the field of culture. Then, identifying the factors of cultural entrepreneurshipstrategies, it offers some models for assessing cultural entrepreneurship strategies and benchmarking it. Afterwards, it tries to reform and standardize the presented model through questioning experts and elite of the profession. It is concluded that there is a significant difference between the mean ranks of the implementation factors of the entrepreneurship strategy which is detailed through the work.

  7. CEGB's radioactive waste management strategy

    International Nuclear Information System (INIS)

    Passant, F.H.; Maul, P.R.

    1989-01-01

    The Central Electricity Generating Board (CEGB) produces low-level and intermediate-level radioactive wastes in the process of operating its eight Magnox and five Advanced Gas Cooled Reactor (AGR) nuclear power stations. Future wastes will also arise from a programme of Pressurised Water Reactors (PWRs) and the decommissioning of existing reactors. The paper gives details of how the UK waste management strategy is put into practice by the CEGB, and how general waste management principles are developed into strategies for particular waste streams. (author)

  8. A belief-based evolutionarily stable strategy.

    Science.gov (United States)

    Deng, Xinyang; Wang, Zhen; Liu, Qi; Deng, Yong; Mahadevan, Sankaran

    2014-11-21

    As an equilibrium refinement of the Nash equilibrium, evolutionarily stable strategy (ESS) is a key concept in evolutionary game theory and has attracted growing interest. An ESS can be either a pure strategy or a mixed strategy. Even though the randomness is allowed in mixed strategy, the selection probability of pure strategy in a mixed strategy may fluctuate due to the impact of many factors. The fluctuation can lead to more uncertainty. In this paper, such uncertainty involved in mixed strategy has been further taken into consideration: a belief strategy is proposed in terms of Dempster-Shafer evidence theory. Furthermore, based on the proposed belief strategy, a belief-based ESS has been developed. The belief strategy and belief-based ESS can reduce to the mixed strategy and mixed ESS, which provide more realistic and powerful tools to describe interactions among agents. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. A value-added strategy

    International Nuclear Information System (INIS)

    Burr, M.T.

    1992-01-01

    This article examines the strategy of Siemens AG of Germany in expanding its role in supplying equipment for the independent power project market. The topics of the article include a description of the organization of the company, cooperation with other companies in development of technology and projects, and future expansion of their build-operate-transfer structure worldwide

  10. Maldives Low Carbon Development Strategy

    DEFF Research Database (Denmark)

    Fenhann, Jørgen Villy; Ramlau, Marianne

    This report presents the findings of a study for low carbon development strategy for Maldives. The study was implemented under the Memorandum of Understanding between the Ministry of Environment and Energy (MEE), Maldives and URC and was financed by Danida, Denmark’s development aid agency under...

  11. Disputing strategies in medieval Scandinavia

    DEFF Research Database (Denmark)

    Orning, Hans Jacob

    In Scandinavia the study of disputes is still a relatively new topic: The papers offered here discuss how conflicts were handled in Scandinavian societies in the Middle Ages before the emergence of strong centralized states. What strategies did people use to contest power, property, rights, honour...... studies. With introductory sections on social structure, sources materials, and the historiography of Scandinavian dispute studies....

  12. Strategy as Mutually Contingent Choice

    Directory of Open Access Journals (Sweden)

    Neil Martin

    2016-05-01

    Full Text Available Thomas Schelling’s The Strategy of Conflict carries significant behavioral implications which have been overlooked by economic readers. I argue that these implications are central to Schelling’s vision of game theory, that they fit well with recent advances in experimental psychology and behavioral economics, and provide a comprehensive framework that can inform research on strategy. In my view, Schelling develops a non-mathematical approach to strategy which anticipates on Gigerenzer and Selten’s “ecological rationality” program. This approach maps the processes involved in strategic reasoning and highlights their reliance on the particular information structure of interactive social environments. Building on this approach, I model strategy as a heuristic form of reasoning that governs the way in which individuals search for and provide cues in situations of mutually contingent choice. I conclude by examining how the reference to ecological rationality can help clarify Schelling’s contribution to game theory and outline potential avenues of research into strategic reasoning and interaction.

  13. Perseverance strategies for enterprising individuals

    NARCIS (Netherlands)

    van Gelderen, M.W.

    2012-01-01

    The purpose of this paper is to arrive at a conceptual understanding of perseverance processes in the context of enterprising behavior and to outline readily employable perseverance strategies for situations characterized by obstacles, challenges and setbacks. This paper presents a process model of

  14. A strategy for company improvement.

    Science.gov (United States)

    Howley, L

    2000-03-01

    Strategies based on the kaizen methodology are designed to continuously improve company performance without the need for large capital investments. This article looks at how one company used simple kaizen principles to its advantage, achieving 67% increase in productivity and 10% reduction in the standard cost of product.

  15. MARKETING STRATEGIES OF PHARMACEUTICAL ORGANIZATION

    Directory of Open Access Journals (Sweden)

    N. M. Sergeeva

    2015-01-01

    Full Text Available Strategy of pharmaceutical goods (PG promotion is a working out of methods of goods realization stimulation. To make PG promotion maximum effective, and to receive a sufficient result for pharmaceutical organization (PO it is necessary to conduct marketing studies (MS, to work out a marketing plan for PG promotion and to offer marketing strategies for goods promotion. To resolve these problems we have formed a concept of marketing promotion of PG system for one of big retail PO of Kursk and Kursk oblast (code name “A”. With this purpose we have identified a problem of PG promotion organization, studied an influence of external and internal environment on the PO “A” activity, determined strong and weak sides of PO activity. We have systematized the results in SWOT-analysis, and formed the strategies of PO for the improvement of work efficiency on the market. On the basis of the results received we have worked out the recommendations for the marketing strategies of PG promotion for the certain PO.

  16. MARKETING STRATEGIES OF SMARTPHONES PRODUCERS

    Directory of Open Access Journals (Sweden)

    Markova V.

    2017-12-01

    Full Text Available Smartphones global market is one of the most dynamically developing markets that can be characterized by high level of competition. The growth of smartphones homogeneity, which is a reduction in difference between technical and functional parameters of smartphones produced by various manufacturers, can be considered the market’s specific feature. The unique situation of high-tech product homogeneity in a fast-growing market is scantily described in specialized literature. The article shows changeability of smartphones global market leaders and explains that the key success factor in such a mature market is marketing. Based on secondary information, marketing strategies of long standing market leader in sales Samsung and overtaking Apple companies are determined as well as strategies of contenders for leadership - Chinese companies Huawei and Lenovo. It is shown on Lenovo case that inexplicit positioning leads to a loss of the growing market share due to offensive marketing strategies of other Chinese companies. The research results broaden the knowledge of methodical potential of marketing strategies in companies’ activities in competitive markets of homogeneous high-tech products.

  17. Skill and strategy in games

    NARCIS (Netherlands)

    Dreef, M.R.M.

    2005-01-01

    This thesis consists of two parts. Part I deals with relative skill and the role of random factors in games. Part II is devoted to the computation of optimal strategies in two interesting classes of games: poker and take-and-guess games.

  18. Trading strategies of corporate insiders

    NARCIS (Netherlands)

    Klein, O.; Maug, E.; Schneider, Christoph

    2017-01-01

    We test two complementary theories of optimal trading strategies by analyzing the transaction patterns of corporate insiders. According to information-based theories, investors trade faster if they compete with others for exploiting the same information, while liquidity-based theories predict the

  19. The Convertible Arbitrage Strategy Analyzed

    NARCIS (Netherlands)

    Loncarski, I.; Ter Horst, J.R.; Veld, C.H.

    2006-01-01

    This paper analyzes convertible bond arbitrage on the Canadian market for the period 1998 to 2004.Convertible bond arbitrage is the combination of a long position in convertible bonds and a short position in the underlying stocks. Convertible arbitrage has been one of the most successful strategies

  20. BNFL decommissioning strategy and techniques

    International Nuclear Information System (INIS)

    Taylor, D.

    2002-01-01

    This paper provides an overview of the range of reactor decommissioning projects being managed by BNFL, both on its own sites and for other client organizations in the UK and abroad. It also describes the decommissioning strategies and techniques that have been developed by BNFL and adopted in order to carry out this work

  1. Active Strategies for Older Workers

    DEFF Research Database (Denmark)

    Hansen, Hans

    This report is also to be published by ETUI (Euruopean Trade Unions' Institute) in a book on Active Strategies for Older Workers. It is the National report for Denmark and contains a short section on characteristics of the Danish labour market, with a special focus on the situation of the elderly...

  2. Strategy selection as rational metareasoning.

    Science.gov (United States)

    Lieder, Falk; Griffiths, Thomas L

    2017-11-01

    Many contemporary accounts of human reasoning assume that the mind is equipped with multiple heuristics that could be deployed to perform a given task. This raises the question of how the mind determines when to use which heuristic. To answer this question, we developed a rational model of strategy selection, based on the theory of rational metareasoning developed in the artificial intelligence literature. According to our model people learn to efficiently choose the strategy with the best cost-benefit tradeoff by learning a predictive model of each strategy's performance. We found that our model can provide a unifying explanation for classic findings from domains ranging from decision-making to arithmetic by capturing the variability of people's strategy choices, their dependence on task and context, and their development over time. Systematic model comparisons supported our theory, and 4 new experiments confirmed its distinctive predictions. Our findings suggest that people gradually learn to make increasingly more rational use of fallible heuristics. This perspective reconciles the 2 poles of the debate about human rationality by integrating heuristics and biases with learning and rationality. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  3. Concurrentie & strategie in de geneesmiddelensector

    NARCIS (Netherlands)

    H. Snier (Henk)

    1995-01-01

    textabstractThe aim of this study is to investigate competition and strategy in the Dutch pharmaceutical sector. Therefore, this study introduces Porters Five Basic Forces model (1980, 1985) to analyze competition in three separate (but connected) industries in the pharmaceutical sector, namely the

  4. Hanford Sitewide Groundwater Remediation Strategy

    International Nuclear Information System (INIS)

    Knepp, A.J.; Isaacs, J.D.

    1997-09-01

    This document fulfills the requirements of the Hanford Federal Facility Agreement and Consent Order, Milestone M-13-81, to develop a concise statement of strategy that describe show the Hanford Site groundwater remediation will be accomplished. The strategy addresses objectives and goals, prioritization of activities, and technical approaches for groundwater cleanup. The strategy establishes that the overall goal of groundwater remediation on the Hanford Site is to restore groundwater to its beneficial uses in terms of protecting human health and the environment, and its use as a natural resource. The Hanford Future Site Uses Working Group established two categories for groundwater commensurate with various proposed landuses: (1) restricted use or access to groundwater in the Central Plateau and in a buffer zone surrounding it and (2) unrestricted use or access to groundwater for all other areas. In recognition of the Hanford Future Site Uses Working Group and public values, the strategy establishes that the sitewide approach to groundwater cleanup is to remediate the major plumes found in the reactor areas that enter the Columbia River and to contain the spread and reduce the mass of the major plumes found in the Central Plateau

  5. Police, managerialization and presentational strategies

    NARCIS (Netherlands)

    Terpstra, J.; Trommel, W.A.

    2009-01-01

    Purpose - The managerialization of the police may be seen as an effort to restore the legitimacy of the police. This paper aims to show that the managerialist strategy presently occurring within police forces creates new pitfalls and unintended consequences. Design/methodology/approach - The paper

  6. Quantum Strategies and Local Operations

    Science.gov (United States)

    Gutoski, Gus

    2010-02-01

    This thesis is divided into two parts. In Part I we introduce a new formalism for quantum strategies, which specify the actions of one party in any multi-party interaction involving the exchange of multiple quantum messages among the parties. This formalism associates with each strategy a single positive semidefinite operator acting only upon the tensor product of the input and output message spaces for the strategy. We establish three fundamental properties of this new representation for quantum strategies and we list several applications, including a quantum version of von Neumann's celebrated 1928 Min-Max Theorem for zero-sum games and an efficient algorithm for computing the value of such a game. In Part II we establish several properties of a class of quantum operations that can be implemented locally with shared quantum entanglement or classical randomness. In particular, we establish the existence of a ball of local operations with shared randomness lying within the space spanned by the no-signaling operations and centred at the completely noisy channel. The existence of this ball is employed to prove that the weak membership problem for local operations with shared entanglement is strongly NP-hard. We also provide characterizations of local operations in terms of linear functionals that are positive and "completely" positive on a certain cone of Hermitian operators, under a natural notion of complete positivity appropriate to that cone. We end the thesis with a discussion of the properties of no-signaling quantum operations.

  7. Student Discipline Strategies: Practitioner Perspectives

    Science.gov (United States)

    Mancini, Joseph A.

    2017-01-01

    This applied dissertation presented a mixed method design to gain a broader perspective of the perceptions of classroom management practitioners within a particular school district. Many teachers, or practitioners, experience issues with classroom management because of their understanding of strategies they use. Because of the researcher's…

  8. Funding strategies for wilderness management

    Science.gov (United States)

    Carolyn Alkire

    2000-01-01

    Funding wilderness protection will continue to be a challenge for public land managers. With continuing competition for federal funds and balanced budget goals, other sources of funds may be necessary to supplement annual federal appropriations. This paper identifies and evaluates five potential funding strategies and provides examples of each that are currently in use...

  9. Strategy-proof social choice

    OpenAIRE

    Barberà, Salvador, 1946-

    2010-01-01

    This paper surveys the literature on strategy-proofness from a historical perspective. While I discuss the connections with other works on incentives in mechanism design, the main emphasis is on social choice models. This article has been prepared for the Handbook of Social Choice and Welfare, Volume 2, Edited by K. Arrow, A. Sen and K. Suzumura

  10. RAFT polymerization mediated bioconjugation strategies

    OpenAIRE

    Bulmuş, Volga

    2011-01-01

    This review aims to highlight the use of RAFT polymerization in the synthesis of polymer bioconjugates. It covers two main bioconjugation strategies using the RAFT process: (i) post-polymerization bioconjugations using pre-synthesized reactive polymers, and (ii) bioconjugations via in situ polymerization using biomolecule-modified monomers or chain transfer agents. © 2011 The Royal Society of Chemistry.

  11. Strategy Implementation and Organizational Change

    DEFF Research Database (Denmark)

    Lynch, Susan E.; Mors, Louise

    2018-01-01

    . This paper considers how formal structural change affects senior managers’ ability to maintain their intraorganizational networks. The hypotheses are tested on sample of 884 work-related relationships of 96 partners in a global professional services firm. This firm had recently implemented a new strategy...

  12. Strategies for Change: Part II.

    Science.gov (United States)

    Atkinson, Hugh C.

    1984-01-01

    Discusses present and future changes in library organization and management resulting from increasingly smaller library units, use of electronics to support decentralized services, new management style, and interlibrary cooperatives. Three strategies for change--to accept change, to change change, to recognize that some things cannot be…

  13. Corporate Strategy an Evolutionary Review

    Science.gov (United States)

    Fellman, Philip V.

    As Richard Rumelt indicates in his book, "Fundamental Issues in Strategy: A Research Agenda", corporate strategy is a relatively recent discipline. While pioneers in the field like B.H. Liddell Hart and Bruce Henderson (later to found the Boston Consulting Group and creator of the famous BCG Growth-Share Matrix) began their research during the Second World War, the modern field of business strategy as an academic discipline, taught in schools and colleges of business emerged rather later. Rumelt provides an interesting chronicle in the introduction to his volume by noting that historically corporate strategy, even when taught as a capstone course, was not really an organized discipline. Typically, depending on the school's location and resources, the course would either be taught by the senior most professor in the department or by an outside lecturer from industry. The agenda tended to be very much instructor specific and idiosyncratic rather than drawing in any systematized fashion upon the subject matter of an organized discipline.

  14. Venture Capital and Innovation Strategies

    NARCIS (Netherlands)

    Da Rin, Marco; Penas, Maria

    2015-01-01

    Venture capital investors are specialized financial intermediaries that provides funding for technological innovation with the goal of realizing a capital gain within a few years. We are the first to examine the association of venture capital funding with a company’s choice of innovation strategies.

  15. Understanding Cognitive Language Learning Strategies

    Directory of Open Access Journals (Sweden)

    Sergio Di Carlo

    2017-01-01

    Full Text Available Over time, definitions and taxonomies of language learning strategies have been critically examined. This article defines and classifies cognitive language learning strategies on a more grounded basis. Language learning is a macro-process for which the general hypotheses of information processing are valid. Cognitive strategies are represented by the pillars underlying the encoding, storage and retrieval of information. In order to understand the processes taking place on these three dimensions, a functional model was elaborated from multiple theoretical contributions and previous models: the Smart Processing Model. This model operates with linguistic inputs as well as with any other kind of information. It helps to illustrate the stages, relations, modules and processes that occur during the flow of information. This theoretical advance is a core element to classify cognitive strategies. Contributions from cognitive neuroscience have also been considered to establish the proposed classification which consists of five categories. Each of these categories has a different predominant function: classification, preparation, association, elaboration and transfer-practice. This better founded taxonomy opens the doors to potential studies that would allow a better understanding of the interdisciplinary complexity of language learning. Pedagogical and methodological implications are also discussed.

  16. Strategies for dark matter detection

    International Nuclear Information System (INIS)

    Silk, J.

    1988-01-01

    The present status of alternative forms of dark matter, both baryonic and nonbaryonic, is reviewed. Alternative arguments are presented for the predominance of either cold dark matter (CDM) or of baryonic dark matter (BDM). Strategies are described for dark matter detection, both for dark matter that consists of weakly interacting relic particles and for dark matter that consists of dark stellar remnants

  17. New Strategies in Cancer Nanomedicine.

    Science.gov (United States)

    Tong, Rong; Kohane, Daniel S

    2016-01-01

    We review recent progress in cancer nanomedicine, including stimulus-responsive drug delivery systems and nanoparticles responding to light for phototherapy or tumor imaging. In addition, several new strategies to improve the circulation of nanoparticles in vivo, tumor penetration, and tumor targeting are discussed. The application of nanomedicine in cancer immunology, a relatively new type of cancer therapy, is also highlighted.

  18. Three directors for one strategy

    CERN Multimedia

    2009-01-01

    Following the interview with the Director General, Rolf-Dieter Heuer, the Bulletin continues its series of interviews with the members of CERN’s new Management team. This week, the Bulletin interviewed the three Directors, who presented their strategies for their respective sectors as a new era begins for CERN.

  19. Venture capital and innovation strategies

    NARCIS (Netherlands)

    Da Rin, Marco; Penas, Fabiana

    2017-01-01

    Venture capital investors are specialized financial intermediaries that provide funding for technological innovation with the goal of realizing a capital gain within a few years. We are the first to examine the association of venture capital funding with a company's choice of innovation strategies.

  20. MUET Preparation Language Learning Strategies

    Directory of Open Access Journals (Sweden)

    Yoong Li Kuen

    2012-01-01

    Full Text Available The main objective of the study was to examine the English language learning strategies (LLS used by Lower Six students in secondary schools who are sitting for their MUET test. It analyzed the language learning strategies that students use in order to prepare for the MUET test. Data were collected using a survey questionnaire with 300 students. The instrument used in this study called “MUET Preparation Language Strategy Use Inventory” is an adapted and bilingual questionnaire designed by Cohen, Oxford and Chi (2005 known as Language Strategy Use Inventory. Forty items were analyzed and they comprised of the four skills tested in MUET which is listening, speaking, reading and writing. Data were analyzed by performing frequency analysis. The findings revealed that the listening skill is the most frequently used, while the writing skill is the least frequently used. Only the listening skill has high frequency of use, while the reading, speaking and writing skills fall under the range of moderate frequency of use. There were variations in responses with regard to the use of LLS among Form Six students in secondary schools. The findings had practical implications.

  1. Management: A Strategy for Change.

    Science.gov (United States)

    White, Herbert S.

    1978-01-01

    Traces the recent history of libraries and mentions loss of status, insufficient funds, insufficient evaluation methods, and unspecified goals as major contributors to contemporary management problems. Also outlined is a management strategy, which includes public relations, long-range and short-range goals, and budget and financing. (JVP)

  2. Strategy Choices of Potential Entrepreneurs

    Science.gov (United States)

    Alstete, Jeffrey W.

    2014-01-01

    The author examined the written business plans of 380 students who completed courses in entrepreneurship and small business management over an 11-year period. An analysis categorized the plans into five generic competitive strategy types, and the results found that 58% chose a traditional, focused differentiation approach. A large portion (28%)…

  3. Recruiting Strategies for Women's Colleges.

    Science.gov (United States)

    Ricci, Ronald J.

    1994-01-01

    Methods for combating declining applicant pools at women's colleges are discussed. Research suggests that effective student recruitment can be facilitated by the use of single-gender market niche as a means for differentiation and parent influence for promotion. Review of strategies currently used indicate these marketing methods are underused and…

  4. Consumption, lifestyles and constellatoric strategies

    DEFF Research Database (Denmark)

    Læssøe, Jeppe

    1996-01-01

    The condtribution reveals a contradiction between complexity and operationality in the discussions about energy consumption between social researchers and policy makers. By mean of two examples from his own research the author argues for a transgression of the narrow ecology-centred view. The first...... of "constellatoric strategies"; coordinated interplays between different coordinated efforts which creates synergy effects....

  5. PRICING STRATEGY FOR DIGITAL PRODUCTS

    Directory of Open Access Journals (Sweden)

    MARIA MAGDALENA CRIVEANU

    2018-02-01

    Full Text Available The current society imposes an alert pace on companies that need to adapt to change, become more flexible and adopt new strategies to maintain market share. Digital marketing is a useful tool for promoting products, as customers can access a range of product information at any time and from anywhere. At the same time, another advantage on the part of companies is the lower promotion costs as compared to traditional promotional methods, as well as the establishment of a connection and a communication bridge with each client. The most important component in the process of purchasing a product is inevitably the price. It communicates a series of information about the product and the customer so that the price can be an important element of persuasion in relation to other marketing strategies. Most of the time, the smallest price is the most important factor in making a decision about buying a product, and digital marketing offers the posibility to compare prices. In this sense, digital marketing can provide both an advantage and a disadvantage for traders, as the small price may invalidate other marketing strategies or product features. In this sense, pricing is a challenge for marketing departments because the pricing strategy is deferring from the sterile formula of pricing which meant covering costs and making profit. This paper aims to analyze the extent to which price is an important element in purchasing a product, as well as highlighting a variety of methods and techniques used in pricing. Quantitative research is based on a questionnaire applied to 100 respondents in order to identify the correct pricing strategy. Research results communicate an important message to merchants who have to adjust the price of each buyer individually, so that the buyer profile is particularly important in setting the price.

  6. Strategies of Legitimacy Through Social Media: The Networked Strategy

    DEFF Research Database (Denmark)

    Castelló, Itziar; Etter, Michael; Nielsen, Finn Årup

    2016-01-01

    the concept of a networked legitimacy strategy. With this strategy, legitimacy is gained through participation in non-hierarchical open platforms and the co-construction of agendas. We explore the organizational transition needed to yield this new legitimacy approach. We argue that, in this context......How can corporations develop legitimacy when coping with stakeholders who have multiple, often conflicting sustainable development (SD) agendas? We address this question by conducting an in-depth longitudinal case study of a corporation's stakeholder engagement in social media and propose......, legitimacy gains may increase when firms are able to reduce the control over the engagements and relate non-hierarchically with their publics. We contribute to the extant literature on political corporate social responsibility and legitimacy by providing an understanding of a new context for engagement...

  7. Crude oil hedging: benchmarking price protection strategies

    International Nuclear Information System (INIS)

    Krapels, Edward N.; Pratt, Michael

    1998-01-01

    This report presents a review of hedging (protection against a loss) strategies in the crude oil futures and options markets. The introductory section of the report gives details of hedging instruments, and the purposes of hedging crude oil. Hedging strategies including pure futures strategies, pure options strategies, options combination strategies, exotic (Asian) options strategies, and insurance instruments are described. The West Texas intermediate (WTI) market depth, liquidity and hedging effectiveness are examined, and winners and losers, and energy consumers are considered. The appendix gives tables and charts summarising the outcomes of futures and options strategies under different market conditions and expectations. (UK)

  8. Energy strategy in the national strategy of economy development

    International Nuclear Information System (INIS)

    Pop-Jordanov, Jordan; Boshevski, Tome; Hadzi-Mishev, Dimitar

    1997-01-01

    This paper is based on the sectorial study on energy, prepared by authors within the project 'National Strategy of Economic Development of Republic of Macedonia', carried out by the Macedonian Academy of Sciences and Arts. The aim is to define the basic lines for the development of energy sector in Macedonia until 2020. The main topics discussed comprise: fuel resources, thermal energy, electric power, price policy, forms of ownership and the environmental impacts. (author)

  9. Strategy analysis frameworks for strategy orientation and focus

    OpenAIRE

    Isoherranen, V. (Ville)

    2012-01-01

    Abstract The primary research target of this dissertation is to develop new strategy analysis frameworks, focusing on analysing changes in strategic position as a function of variations in life cycle s-curve/time/typology/market share/orientation. Research is constructive and qualitative by nature, with case study methodology being the adopted approach. The research work is carried out as a compilation dissertation containing four (4) journal articles. The theoretical framework of thi...

  10. How to integrate Investment strategies and Finance strategies. Case: Messukeskus

    OpenAIRE

    Kolodiy, Oleg

    2013-01-01

    This Bachelor’s thesis examines an integration process of strategic planning, where an investment strategy is defined with financial planning in order to ensure long-term company success. The primary objective of the study is to determine present and emerging instruments available for a case company to finance their investments activities. The thesis consists of a theory section and an empirical section that deals with the commissioning party, a cooperative by form. The theory sectio...

  11. The concept of Ideal Strategy & its realization using White Ocean Mixed Strategy

    OpenAIRE

    Sreeramana Aithal

    2016-01-01

    Strategic planning and decision making have an important role in organizational development and sustainability. Various types of strategies are used in strategic management such as Red ocean strategy, Blue ocean strategy, Green ocean strategy, Purple ocean strategy and Black ocean strategy. These strategies are used in organizations by top level executive managers for long-term organizational sustainability and to face or deviate from the competition. Based on organizational analy...

  12. The concept of Ideal Strategy and its realization using White Ocean Mixed Strategy

    OpenAIRE

    Aithal, Sreeramana

    2016-01-01

    Strategic planning and decision making have an important role in organizational development and sustainability. Various types of strategies are used in strategic management such as Red ocean strategy, Blue ocean strategy, Green ocean strategy, Purple ocean strategy and Black ocean strategy. These strategies are used in organizations by top level executive managers for long term organizational sustainability and to face or deviate from the competition. Based on the organizational analysis, it...

  13. Emergent strategies of electricity producers

    International Nuclear Information System (INIS)

    Van der Woerd, F.; Lise, W.; Becker, G.

    2004-10-01

    The EU-funded research project EMELIE (Electricity Market Liberalisation In Europe) wants to provide a sound analysis of the economic and environmental impacts of the liberalisation process of the European electricity markets. The EMELIE model simulates various market scenarios. The companies in the EMELIE model are assumed to have a relatively simple strategy, i.e. profit maximisation, which is constrained by trade limitation, emission quota, and available production capacity for various technologies. The Institute for Environmental Studies (IVM) took the initiative to start a complementary line of research. At a more detailed level, we investigated business strategies from the perspective of the companies themselves: What is their dominant strategy in the process of liberalisation? Why do they behave like that? What will be the likely strategy of dominant companies in the years to come? And last but not least: how does this most likely strategy fit into the stylised EMELIE scenarios? In our analysis, we use theories about business behaviour, like the Portfolio Analysis of the Boston Consulting Group and Porter's Typology of Business Strategies. We also consider two theories that relate to company-authority interactions: Williamson's New Institutional Economics that compares market failures with government failures and Tinbergen's Theory of Economic Policy, that warns for exaggerated expectations of a single policy instrument, in this case market liberalisation. We observe that the liberalisation process has brought about a wave of mergers and acquisitions, resulting in concentrated markets. Concentration Standards of Competition Authorities decide on maximum concentration levels, not the market itself. The trend towards market concentration originates because dominant companies want to avoid price competition and consider strategic market behaviour in their best interest. These expansionist' companies prefer proven production technologies with low variable costs

  14. Strategies for Aging in Place

    Directory of Open Access Journals (Sweden)

    Suzanne Dupuis-Blanchard

    2015-01-01

    Full Text Available For healthy and independent older adults, aging in place can be seen as identical to any other adult living at home. Little is known about how frail seniors, particularly those who speak a minority language, manage the challenges of aging in place. The present qualitative descriptive study explores the strategies that Canadian French-speaking seniors have put in place to counter their loss of independence and promote their ability to stay in their home. Semistructured individual interviews were conducted with 39 older adults and transcribed, followed by content analysis to identify common themes related to study objectives. Six themes emerged in response to strategies described for aging in place. Findings reveal the limited extent to which language issues were perceived as a barrier by participants. In conclusion, the results of this study provide us with fruitful insights to guide community nursing practice, future research, and public policy.

  15. Identity style and coping strategies.

    Science.gov (United States)

    Berzonsky, M D

    1992-12-01

    This study examined the relationship between identity style and strategies used to cope with stressors that potentially threaten one's sense of identity. Identity style refers to differences in the way individuals construct and revise or maintain their sense of identity. An informational style involves actively seeking out, evaluating, and utilizing self-relevant information. A normative style highlights the expectations and standards of significant others. A diffuse/avoidant style is characterized by procrastination and situation-specific reactions. Late-adolescent college subjects were administered measures of identity style, ways of coping with academic stressors, and test anxiety. Within this self-as-student context, subjects with diffuse and normative identity styles employed avoidant-oriented coping strategies (wishful thinking, distancing, and tension reduction). An informational style was associated with deliberate, problem-focused coping. Findings are discussed in terms of a process model of identity development.

  16. Heuristic Strategies in Systems Biology

    Directory of Open Access Journals (Sweden)

    Fridolin Gross

    2016-06-01

    Full Text Available Systems biology is sometimes presented as providing a superior approach to the problem of biological complexity. Its use of ‘unbiased’ methods and formal quantitative tools might lead to the impression that the human factor is effectively eliminated. However, a closer look reveals that this impression is misguided. Systems biologists cannot simply assemble molecular information and compute biological behavior. Instead, systems biology’s main contribution is to accelerate the discovery of mechanisms by applying models as heuristic tools. These models rely on a variety of idealizing and simplifying assumptions in order to be efficient for this purpose. The strategies of systems biologists are similar to those of experimentalists in that they attempt to reduce the complexity of the discovery process. Analyzing and comparing these strategies, or ‘heuristics’, reveals the importance of the human factor in computational approaches and helps to situate systems biology within the epistemic landscape of the life sciences.

  17. MANAGEMENT STRATEGIES DURING ECONOMIC CRISIS

    Directory of Open Access Journals (Sweden)

    SINTEA(ANGHEL LUCICA

    2014-05-01

    Full Text Available During the financial and economic crisis, the management of an entity must establish a plan and apply strategies needed to mitigate the negative effects due to the action of disturbing factors. Management must have a vision of business evolution, of costumer and supplier perspective, of how to develop the technological equipment in order to increase profitability and product quality. The manager must give utmost importance to all economic information he receives, to analyze it, to group it into categories depending on the effects they can produce, to establish the extent to which it influences the activity. The strategies a manager applies are also based on his flair, culture, knowledge or the human and material resources at its disposal

  18. Life history types and strategies

    DEFF Research Database (Denmark)

    Boel, Mikkel

    strategies and types in migratory freshwater fish, using brown trout and alewife as study organisms. Firstly, we investigated underlying mechanisms of resident and migratory life history strategies of salmonids, using indicators for nutritional status, stress, tissue damage and smoltification. Secondly...... III the minimum predation from cormorants and herons was estimated over a three year period on the brown trout population of of Lake Hald. The magnitude of the predation pressure from both bird species were very similar and when summed up, the avian predation accounted for an average minimum of 37.......2 % of the annual brown trout mortality in the lake and 10.1 % in the tributaries. This result illustrates that avian predation in the lake can be quite substantial and potentially plays an important role in the population dynamics of brown trout. Cormorants alone were responsible 21.2% in the lake and the arrival...

  19. Legitimacy Strategy in Institutional Multiplicities

    DEFF Research Database (Denmark)

    Rana, Mohammad Bakhtiar; Marinova, Svetla Trifonova; Sørensen, Olav Jull

    2014-01-01

    research: adaptation, bypass, manipulation, and intervention/innovation. However, the paper goes further by presenting an operational framework for legitimacy strategy, postulating that it is grounded in the ‘corporate commitment’ of MNEs and is operationalized either by ‘corporate initiative......This paper focuses on ‘institutional void’ (IV) and ‘civil society’ (CS). Investigating five European MNEs in a fragmented business system by using a multiple-case-study method and a sense-making approach, we explore how IV and CS affect MNEs and how MNEs respond to them in pursuit of legitimacy....... Our study reveals three forms of IV, i.e., system void, value chain void, and void between social need and citizen services, and two broad roles of CS, being an enabler and constrainer that affect MNE operations and survival. We validate four types of legitimacy strategies presented by previous...

  20. Quantum Locality in Game Strategy.

    Science.gov (United States)

    Melo-Luna, Carlos A; Susa, Cristian E; Ducuara, Andrés F; Barreiro, Astrid; Reina, John H

    2017-03-22

    Game theory is a well established branch of mathematics whose formalism has a vast range of applications from the social sciences, biology, to economics. Motivated by quantum information science, there has been a leap in the formulation of novel game strategies that lead to new (quantum Nash) equilibrium points whereby players in some classical games are always outperformed if sharing and processing joint information ruled by the laws of quantum physics is allowed. We show that, for a bipartite non zero-sum game, input local quantum correlations, and separable states in particular, suffice to achieve an advantage over any strategy that uses classical resources, thus dispensing with quantum nonlocality, entanglement, or even discord between the players' input states. This highlights the remarkable key role played by pure quantum coherence at powering some protocols. Finally, we propose an experiment that uses separable states and basic photon interferometry to demonstrate the locally-correlated quantum advantage.

  1. Strategies for Living in Houses

    Directory of Open Access Journals (Sweden)

    Colin Ripley

    2017-12-01

    Full Text Available The problem of queer housing can never go away because it is a central component of queerness. Queer housing is a contradiction in terms: not even a queer architect can design a queer house. But where does this leave us, as queer people living in a straight hegemony? Where does it leave us as humans with bodies, craving shelter and safety and a place to live that is in accordance with our experience of self and of living in the world? In this article the author proposes eight architectural strategies for re-occupying the Levittown Cape Cod house from 1947 for queer bodies, minds and hearts. These strategies offer modes by which the key programmatic formal and material components of the Cape Cod House can be attacked, made invalid, or détourned for queer uses, to make of the Cape Cod House a site for our pain, our longing, our anger.

  2. Disputing strategies in medieval Scandinavia

    DEFF Research Database (Denmark)

    Orning, Hans Jacob

    In Scandinavia the study of disputes is still a relatively new topic: The papers offered here discuss how conflicts were handled in Scandinavian societies in the Middle Ages before the emergence of strong centralized states. What strategies did people use to contest power, property, rights, honour......, and other kinds of material or symbolic assets? Seven essays by Scandinavian scholars are supplemented by contributions from Stephen White, John Hudson and Gerd Althoff, to provide a new baseline for discussing both the strategies pursued in the political game and those used to settle local disputes. Using...... practice and process as key analytical concepts, these authors explore formal law and litigation in conjunction with non-formal legal proceedings such as out-of-court mediation, rituals, emotional posturing, and feuding. Their insights place the Northern medieval world in a European context of dispute...

  3. Quantum Locality in Game Strategy

    Science.gov (United States)

    Melo-Luna, Carlos A.; Susa, Cristian E.; Ducuara, Andrés F.; Barreiro, Astrid; Reina, John H.

    2017-03-01

    Game theory is a well established branch of mathematics whose formalism has a vast range of applications from the social sciences, biology, to economics. Motivated by quantum information science, there has been a leap in the formulation of novel game strategies that lead to new (quantum Nash) equilibrium points whereby players in some classical games are always outperformed if sharing and processing joint information ruled by the laws of quantum physics is allowed. We show that, for a bipartite non zero-sum game, input local quantum correlations, and separable states in particular, suffice to achieve an advantage over any strategy that uses classical resources, thus dispensing with quantum nonlocality, entanglement, or even discord between the players’ input states. This highlights the remarkable key role played by pure quantum coherence at powering some protocols. Finally, we propose an experiment that uses separable states and basic photon interferometry to demonstrate the locally-correlated quantum advantage.

  4. Development Strategy for Slovak society

    International Nuclear Information System (INIS)

    Sikula, V.

    2010-01-01

    In this book authors analyse the present state of economy as well as strategy of perspectives of development of Slovak society. A key issue in the next 5 to 10 years in the energy sector will mainly address energy security, diversification of energy sources, renewable energy sources and energy savings. The strategic goal is to transform energy into a form that will ensure long competition-capable and reliable supply of all forms of energy, taking into account sustainable development, security of supply and technical security. The strategy of energy security of Slovakia in 2030 is to achieve a competitive energy industry, ensuring safe, reliable and efficient supply of all forms of energy at affordable prices with regard to consumer protection, environmental protection, sustainable development, security of supply and technical security.

  5. COINCO Strategy 2025 - Discussion Paper

    DEFF Research Database (Denmark)

    Jespersen, Per Homann; Jensen, Anne; Stroschein, Christoph

     The regions and cities in the COINCO-corridor Oslo-Göteborg-Malmö-Copenhagen-Berlin have worked out a strategy proposal which is presented in this discussion paper. Behind the strategy is a political will to utilize mutual strengths and together become a leading player in a globalized world, based...... on matters essential to development - ‘hard' issues such as transport infrastructure and ‘soft' issues on improving cooperation within business, administration and knowledge production. The synergy of COINCO will have to come from collaboration among businesses. Supporting cooperation between existing...... to be institutionally supported. Therefore a number of knowledge institutions have to be formed organized around the ‘triple helix'-principle - a tight collaboration between business, administration and knowledge producers, especially universities. Also new ways of collaboration have to be explored - ‘network...

  6. Water Saving Strategies & Ecological Modernisation

    DEFF Research Database (Denmark)

    Hoffmann, Birgitte; Jensen, Jesper Ole; Elle, Morten

    2005-01-01

    Drawing on case studies of water saving campaigns and new collaborations, the pa-per will serve, on the one hand, as an interpretation of the water saving strategy in Co-penhagen in the light of Ecological Modernisation, and on the other hand, as a critical discussion of Ecological Modernisation...... as a frame for understanding resource manage-ment. The water management in Copenhagen has in recent years undergone a rather radi-cal transition. Along with strong drivers for resource management in the region the mu-nicipal water supplier has tested and implemented a number of initiatives to promote sus...... to 125 l/capita/day in 2002. A series of different strategies, targets and tools have been implemented: Emphasizing demand side instead of supply side, using and communicating indicators, formulating goals for reducing water consumption and developing learning processes in water management. A main...

  7. Cost reducing code implementation strategies

    International Nuclear Information System (INIS)

    Kurtz, Randall L.; Griswold, Michael E.; Jones, Gary C.; Daley, Thomas J.

    1995-01-01

    Sargent and Lundy's Code consulting experience reveals a wide variety of approaches toward implementing the requirements of various nuclear Codes Standards. This paper will describe various Code implementation strategies which assure that Code requirements are fully met in a practical and cost-effective manner. Applications to be discussed includes the following: new construction; repair, replacement and modifications; assessments and life extensions. Lessons learned and illustrative examples will be included. Preferred strategies and specific recommendations will also be addressed. Sargent and Lundy appreciates the opportunity provided by the Korea Atomic Industrial Forum and Korean Nuclear Society to share our ideas and enhance global cooperation through the exchange of information and views on relevant topics

  8. Strategy for tactical cellular connectivity

    Science.gov (United States)

    Carlson, Frederick R.

    2011-06-01

    This paper proposes a strategy to unify four disparate networks under an Internet Protocol (IP) umbrella. The first network is the Army Warfighter Information Network - Tactical (WIN-T) area common user system. The second network is an extension to the area common user system using the Mobile Ad Hoc Interoperability Networking Gateway (MAINGATE) system. The third network is the Worldwide Interoperability for Microwave Access (WiMax) based wireless access network and the forth network is the 802.11 WiFi Network. It is the intent of this paper to propose a skeletal wireless strategy that at its core will create everything over IP (EoIP) and "Everything over IEEE" ("EoIEEE") standards at the tactical level of the battlefield.

  9. Machine learning for evolution strategies

    CERN Document Server

    Kramer, Oliver

    2016-01-01

    This book introduces numerous algorithmic hybridizations between both worlds that show how machine learning can improve and support evolution strategies. The set of methods comprises covariance matrix estimation, meta-modeling of fitness and constraint functions, dimensionality reduction for search and visualization of high-dimensional optimization processes, and clustering-based niching. After giving an introduction to evolution strategies and machine learning, the book builds the bridge between both worlds with an algorithmic and experimental perspective. Experiments mostly employ a (1+1)-ES and are implemented in Python using the machine learning library scikit-learn. The examples are conducted on typical benchmark problems illustrating algorithmic concepts and their experimental behavior. The book closes with a discussion of related lines of research.

  10. Treatment Strategies for Chronic Cases

    Directory of Open Access Journals (Sweden)

    Susan M Lord

    2003-01-01

    Full Text Available The treatment of chronic somatic pain, including pain referred to the head, neck, shoulder girdle and upper limb from somatic structures, is addressed. Levels of evidence for the various treatments that have been prescribed for chronic whiplash associated disorders are considered. The challenge to find a treatment strategy for chronic pain after whiplash that completely relieves the condition and prevents its sequelae is reviewed.

  11. The CR-Marketing Strategy

    OpenAIRE

    Pricop Oliver Constantin

    2011-01-01

    The Customer Relationship- Marketing supposes the adaptation of the marketing mix from the customers’ and the market’s perspective. Thus, the 4 P (product, price, place, promotion) must become 4 D (desired by consumers, distinctive from the competition, deliverable by the company, durable over time) respectively 4C (the buyer with his requirements and desires, the cost paid by the buyer, the convenience of the acquisition, the communication with the customers. The CR-Marketing strategy compri...

  12. Analysis of Samsung notebook strategy

    OpenAIRE

    Xu, Rui

    2009-01-01

    Under the fast growing background, Notebook industry draws lots attention from IT companies. It is expected that by 2010, the sales of notebook will overrun the sales of desktop. After the SWOT and SPACE analysis, we recommend Samsung to improve from two different perspectives, first, set up a clear and detailed marketing goal and plan, and ensure the enforcing of such strategies. Secondly, manage the distribution channels effectively and efficiently. There are two trends Samsu...

  13. Introduction strategies raise key questions.

    Science.gov (United States)

    Finger, W R; Keller, S

    1995-09-01

    Key issues that must be considered before a new contraceptive is introduced center on the need for a trained provider to begin or terminate the method, its side effects, duration of use, method's ability to meet users' needs and preferences, and extra training or staff requirements. Logistics and economic issues to consider are identifying a dependable way of effectively supplying commodities, planning extra services needed for the method, and cost of providing the method. Each contraceptive method presents a different side effect pattern and burdens the service delivery setting differently. The strategy developed to introduce or expand the 3-month injectable Depo-Provera (DMPA) can be used for any method. It includes a needs assessment and addresses regulatory issues, service delivery policies and procedures, information and training, evaluation, and other concerns. Viet Nam's needs assessment showed that Norplant should not be introduced until the service delivery system becomes stronger. Any needs assessment for expansion of contraceptive services should cover sexually transmitted disease/HIV issues. A World Health Organization strategy helps officials identify the best method mix for local situations. Introductory strategies must aim to improve the quality of family planning programs and expand choices. Many begin by examining existing data and conducting interviews with policymakers, users, providers, and women's health advocates. Introductory programs for Norplant focus on provider training, adequate counseling and informed consent for users, and ready access to removal. They need a well-prepared service delivery infrastructure. The first phase of the DMPA introductory strategy for the Philippines comprised a social marketing campaign and DMPA introduction at public clinics in 10 pilot areas with strong service delivery. Successful AIDS prevention programs show that people tend to use barrier methods when they are available. USAID is currently studying

  14. National HIV/AIDS Strategy

    Centers for Disease Control (CDC) Podcasts

    2012-02-01

    Dr. Kevin Fenton, Director of CDC’s National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, talks about the importance of the National HIV/AIDS Strategy and the work of CDC.  Created: 2/1/2012 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP).   Date Released: 2/1/2012.

  15. MARKETING STRATEGY IN SPORTS SPONSORSHIP

    OpenAIRE

    Srećko Novaković

    2012-01-01

    Sponsorship, as a very successful form of marketing, is quite common in sports. Thanks to the financial means which come from sponsorship, sports teams and individuals achieve top results. In return for that, sponsors take advantage by enhancing their brand and image for longer period. An extensive influence of sponsorship over sports development has been achieved through properly selected elements of sports strateg.y

  16. Diabetes Prevention and Treatment Strategies

    OpenAIRE

    Backholer, Kathryn; Peeters, Anna; Herman, William H.; Shaw, Jonathan E.; Liew, Danny; Ademi, Zanfina; Magliano, Dianna J.

    2013-01-01

    OBJECTIVE Effective interventions to prevent, delay, or remit diabetes are currently available. However, their impact on the prevalence of diabetes at the population level is unknown. This study aimed to estimate the impact of a range of diabetes interventions on the population prevalence of diabetes for Australian adults between 2010 and 2025. RESEARCH DESIGN AND METHODS We used the Australian Diabetes Projection Model to estimate the impact of a population-wide strategy, high-risk preventio...

  17. Cognitive Strategies and Skill Acquisition.

    Science.gov (United States)

    1981-02-09

    Behavior (Acadmic Press, N.Y., 1974). ( 9). Craik , F.I.M., 8 Lockhart , R.S., Levels of processing : A frame- work for memory research, Journal of...C.D., a Stein, B.S., Some general constraints on learning and memory research, in: F.I.M. Craik 6 L.S. Cermak.(eds.), Levels of Processing and...instructions, or instructions in the use of particular strategies. (Belmont & Butterfield, 1971; Craik & Lockhart , 1972; Weinstein, 1978) have had

  18. Supply strategy for SMR deployment

    International Nuclear Information System (INIS)

    Coccagna, A.F.

    2013-01-01

    This document provides a description of Babcock and Wilcox's deployment strategy for the mPower™ Small Modular Reactor from the perspective of Supply Chain and Manufacturing. A desirable future state of readiness is described as one which leverages and revitalizes an existing supply chain and manufacturing infrastructure, as well as leveraging an existing workforce of engineering, construction, and project management employees. B and W's mPower™ SMR value proposition offers many desired design and operating advantages to the SMR market. (author)

  19. Gas de France international strategy

    International Nuclear Information System (INIS)

    Deyirmendjian, J.

    1993-01-01

    This paper presents the main international objectives of Gaz de France, and actions taken to achieve them. The safety and the reliability of natural gas supplies is the priority-holder axis of the international strategy of Gaz de France. The second axis is to obtain a consolidated position in Europe on natural gas markets and valorize the know-how of Gaz de France in foreign countries

  20. Scottish Nuclear's information systems strategy

    International Nuclear Information System (INIS)

    Inglis, P.

    1991-01-01

    Scottish Nuclear, the company which has owned and operated Scotland's nuclear power generating capacity since privatization, inherited a substantial amount of computer hardware and software from its predecessor, the South of Scotland Electricity Board. Each of the two power stations, Torness and Hunterston, were using Digital Vax clusters as the Scottish Nuclear company was formed. This had a major influence on the information systems strategy which has subsequently been adopted. (UK)

  1. Decision Strategy Research: Policy Support

    International Nuclear Information System (INIS)

    Hardeman, F.

    2000-01-01

    The objective of SCK-CEN's R and D programme on decision strategy research are (1) to support and advise the Belgian authorities on specific problems concerning existing and potential hazards from exposure to ionising radiation, both in normal and emergency situations; (2) to perform research on relevant topics that might have an important impact on decision making related to nuclear applications, including social and economic sciences. Main achievements in this area in 1999 are described

  2. Virtual laboratory strategies for development

    International Nuclear Information System (INIS)

    Canessa, Enrique; Fonda, Carlo; Radicella, Sandro M.

    2001-08-01

    We present an overview of the VL approach to promote research and education in developing countries and to help reduce the technology gap of the digital divide. We discuss software tools for instrument control, data sharing and e-collaboration with special attention on low-bandwidth networks. We analyse the VL tentative costs involved and the skills needed for the VL administration. We conclude by identifying some VL strategies for development. (author)

  3. MARKETING STRATEGY IN SPORTS SPONSORSHIP

    Directory of Open Access Journals (Sweden)

    Srećko Novaković

    2012-09-01

    Full Text Available Sponsorship, as a very successful form of marketing, is quite common in sports. Thanks to the financial means which come from sponsorship, sports teams and individuals achieve top results. In return for that, sponsors take advantage by enhancing their brand and image for longer period. An extensive influence of sponsorship over sports development has been achieved through properly selected elements of sports strateg.y

  4. Strategies that fit emerging markets.

    Science.gov (United States)

    Khanna, Tarun; Palepu, Krishna G; Sinha, Jayant

    2005-06-01

    It's no easy task to identify strategies for entering new international markets or to decide which countries to do business with. Many firms simply go with what they know-and fall far short of their goals. Part of the problem is that emerging markets have "institutional voids": They lack specialized intermediaries, regulatory systems, and contract-enforcing methods. These gaps have made it difficult for multinationals to succeed in developing nations; thus, many companies have resisted investing there. That may be a mistake. If Western companies don't come up with good strategies for engaging with emerging markets, they are unlikely to remain competitive. Many firms choose their markets and strategies for the wrong reasons, relying on everything from senior managers' gut feelings to the behaviors of rivals. Corporations also depend on composite indexes for help making decisions. But these analyses can be misleading; they don't account for vital information about the soft infrastructures in developing nations. A better approach is to understand institutional variations between countries. The best way to do this, the authors have found, is by using the five contexts framework. The five contexts are a country's political and social systems, its degree of openness, its product markets, its labor markets, and its capital markets. By asking a series of questions that pertain to each ofthe five areas, executives can map the institutional contexts of any nation. When companies match their strategies to each country's contexts, they can take advantage of a location's unique strengths. But first firms should weigh the benefits against the costs. If they find that the risks of adaptation are too great, they should try to change the contexts in which they operate or simply stay away.

  5. Strategies for the plutonium utilization

    International Nuclear Information System (INIS)

    Zouain, D.M.; Lima, J.O.V.; Sakamoto, L.H.

    1981-11-01

    A review of the activities involving plutonium (its recycle, utilization and technological status and perspectives) is done. These informations are useful for an economic viability study for the plutonium utilization in thermal reactors (recycling) and in fast breeders reactor (FBR), trying to collect the major number of informations about these subjects. The initial phase describes the present status and projections of plutonium accumulation and requirements. Then, the technological process are described and some strategies are analyzed. (E.G.) [pt

  6. Auditing Marketing Strategy Implementation Success

    OpenAIRE

    Herhausen, Dennis; Egger, Thomas; Oral, Cansu

    2014-01-01

    What makes a marketing strategy implementation successful and how can managers measure this success? To answer these questions, we developed a two-step audit approach. First, managers should measure the implementation success regarding effectiveness, efficiency, performance outcomes, and strategic embeddedness. Second, they should explore the reasons that have led to success or failure by regarding managerial, leadership, and environmental traps. Doing so will also provide corrective action p...

  7. Strategies and logics of internationalization

    Directory of Open Access Journals (Sweden)

    Mahjouba Ben Salem

    2013-07-01

    Full Text Available The race between firms to acquire capacities worldwide has evolved in a chronological order which centered at first around products, then around position to move later on to skills and to focus currently on networks. Similarly, when observing the evolution of the different international development strategies, it was found out that they have started by the exportation and the setting up of production subsidiaries to move more recently to such strategies as mergers & acquisitions and international alliances. The present paper investigates the relationship between the internationalization strategies and logics and comes to the conclusion that, a particular logic is behind every choice made. Indeed, the present work was conducted within the Tunisian food enterprises and helped confirm this hypothesis as it was found out that the position logic is behind the choice of exportation and the creation of production subsidiaries while the choice of partnership is based on the logic of skills. The option for merger, on the other hand, is motivated by the networks logic.

  8. Market Strategies for Climate Change

    Energy Technology Data Exchange (ETDEWEB)

    Kolk, A.; Pinkse, J. [Business School, University of Amsterdam, Amsterdam (Netherlands)

    2004-06-01

    The issue of climate change has attracted increasing business attention in the past decade. Whereas companies initially aimed primarily at influencing the policy debate, corporate strategies increasingly include economic responses. Existing classifications for climate change strategies however still reflect the political, non-market components. Using empirical information from the largest multinational companies worldwide, this article examines current market responses, focusing on the drivers (threats and opportunities) and the actions being taken by companies to address climate change. It also develops a typology of climate strategies that addresses the market dimensions, covering both the aim (strategic intent) and the degree of cooperation (form of organisation). The aim turns out to be either innovation or compensation, while the organisational arrangements to reach this objective can be oriented at the company level (internal), at companies' own supply chain (vertical) or at cooperation with other companies (competitors or companies in other sectors - horizontal). The typology can assist managers in deciding about the strategic option(s) they want to choose regarding climate change, also based on the insights offered by the paper about the current state of activities of other companies worldwide.

  9. Strategies for Translating Vocative Texts

    Directory of Open Access Journals (Sweden)

    Olga COJOCARU

    2014-12-01

    Full Text Available The paper deals with the linguistic and cultural elements of vocative texts and the techniques used in translating them by giving some examples of texts that are typically vocative (i.e. advertisements and instructions for use. Semantic and communicative strategies are popular in translation studies and each of them has its own advantages and disadvantages in translating vocative texts. The advantage of semantic translation is that it takes more account of the aesthetic value of the SL text, while communicative translation attempts to render the exact contextual meaning of the original text in such a way that both content and language are readily acceptable and comprehensible to the readership. Focus is laid on the strategies used in translating vocative texts, strategies that highlight and introduce a cultural context to the target audience, in order to achieve their overall purpose, that is to sell or persuade the reader to behave in a certain way. Thus, in order to do that, a number of advertisements from the field of cosmetics industry and electronic gadgets were selected for analysis. The aim is to gather insights into vocative text translation and to create new perspectives on this field of research, now considered a process of innovation and diversion, especially in areas as important as economy and marketing.

  10. Arsenic Hyperaccumulation Strategies: An Overview

    Directory of Open Access Journals (Sweden)

    Zahra Souri

    2017-07-01

    Full Text Available Arsenic (As pollution, which is on the increase around the world, poses a growing threat to the environment. Phytoremediation, an important green technology, uses different strategies, including As uptake, transport, translocation, and detoxification, to remediate this metalloid. Arsenic hyperaccumulator plants have developed various strategies to accumulate and tolerate high concentrations of As. In these plants, the formation of AsIII complexes with GSH and phytochelatins and their transport into root and shoot vacuoles constitute important mechanisms for coping with As stress. The oxidative stress induced by reactive oxygen species (ROS production is one of the principal toxic effects of As; moreover, the strong antioxidative defenses in hyperaccumulator plants could constitute an important As detoxification strategy. On the other hand, nitric oxide activates antioxidant enzyme and phytochelatins biosynthesis which enhances As stress tolerance in plants. Although several studies have focused on transcription, metabolomics, and proteomic changes in plants induced by As, the mechanisms involved in As transport, translocation, and detoxification in hyperaccumulator plants need to be studied in greater depth. This review updates recent progress made in the study of As uptake, translocation, chelation, and detoxification in As hyperaccumulator plants.

  11. Strategi Public Relations Pariwisata Bali

    Directory of Open Access Journals (Sweden)

    Kadek Dwi Cahaya Putra

    2013-12-01

    Full Text Available Abstract: Bali has to maintain its image and reputation as the world leading class tourist destination. Tourism in fact is a vulnerable industry easily ruined by related issues and crises. Therefore, Public Relations (PR with its communication strategy is highly required to maintain good relationships with related parties. This study is aimed at identifying Bali’s Public Relations positioning and setting up its PR strategies. Data and information are gained by means of questionnaire distributed to The Bali Tourism Board (BTB with its stakeholders as an organization playing important role in Bali tourism. The data is then analyzed by SWOT (Strength Weaknesses Opportunities and Threats analysis. It is then found that Bali’s PR positioning is on quadrant V means Stabilization/Growth. The appropriate strategies then are socializing the importance of Issue and Crisis Management, be more creative in tourism related special events, developing relationships with medias, improving tourism publication’s quality, maintaining relationships with related tourism organization and Bali community internally.

  12. Personality and Emotion Regulation Strategies

    Directory of Open Access Journals (Sweden)

    Esti Hayu Purnamaningsih

    2017-01-01

    Full Text Available The emotions has many important functions in our life such as in relation of interpersonal communication, and health. In interpersonal communicative function aimed to signal to other information about internal state. Emotions manifests in specific cognitive, behavioural, and physiological reactions, thus closely related to health. There is wide variety of ways for individuals to regulate their emotion. In this regard, there are two kinds of emotion regulation strategy; first Antecedent-focused emotion regulation consisting of situation selection, situation modification, attentional deployment, cognitive change and second, Response-focused emotion regulation consisting of suppression. The purpose of this research is to investigate personality factors relate with emotion regulation strategies. 339 students from Faculty of Psychology, Universitas Gadjah Mada were participating in this study and given The Big Five Personality Factors (Ramdhani, 2012, adaptation, and the modified version of the Emotion Regulation Scale was used, Emotion Regulation Questionnaire (John & Gross, 2004 which measure personality and emotion regulation respectively. Using multiple regression analysis, the study indicated that personality predicts emotion regulation strategies.

  13. Scenarios and Strategies for Africa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-11-15

    In 2011, IRENA will start developing scenarios and strategies for Africa. This is a pilot study for a project that will ultimately encompass the whole world. The selection of Africa first indicates the priority that the IRENA work programme places on the continent. In the framework of the 2011 IRENA work programme, the analysis of scenarios and strategies will feed into the renewables readiness assessment, which will assess policy priorities and best practices in renewable energy policy-making. This, in turn, will be the basis for financing investment and capacity building activities. Energy policy advice must consider issues, such as the structure of energy supply and demand, the past and future energy trends, renewable energy resources, energy economics and technology access. Scenarios and strategies are key tools for such an analysis. Regional and national differences must be considered and individual sectors and end-use categories further analysed. These include power generation, cooking, heating, industrial process heat, and transport. Urban and rural solutions will be dealt with separately, as well as centralised and decentralised solutions. The analysis will cover issues, such as potentials, technology, supply chains and investment needs.

  14. PERUMUSAN STRATEGI PERUSAHAAN BERDASARKAN COMPETITIVE ADVANTAGE

    Directory of Open Access Journals (Sweden)

    Endah Utami

    2012-12-01

    Full Text Available Perusahaan Tenun Ikat Lestari Indah adalah perusahaan pembuatan kain dengan alat tenun bukan mesin. Dalam menjalankan bisnisnya, perusahaan menghadapi berbagai kendala, diantaranya daya beli masyarakat menurun akibat situasi perekonomian yang tidak menentu serta persaingan harga yang tidak sehat antar pengrajin. Tujuan penelitian ini adalah untuk merumuskan strategi perusahaan sesuai dengan kondisi internal dan eksternal perusahaan. Metode yang digunakan dalam penelitian ini adalah analisis SWOT, I-E (Internal-External, dan QSPM (Quantitative Strategy Planning Matrix. Hasil penelitian menunjukkan posisi bisnis perusahaan berada pada posisi pertumbuhan, sehingga strategi yang dirumuskan adalah menghindari kehilangan profit dan penjualan. Dari hasil analisis QSPM (Quantitative Strategy Planning Matrix diketahui strategi yang terpilih untuk strategi jangka pendek adalah menjalin hubungan baik dengan konsumen tetap , strategi jangka pendek-menengah adalah menjalin kerjasama dengan biro-biro perjalanan wisata, strategi jangka menengah adalah menetapkan tingkatan harga sesuai kualitas dan desain, dan strategi jangka panjang adalah memperluas jaringan pemasaran di dalam dan luar negeri.

  15. The notion of strategy in facility management

    DEFF Research Database (Denmark)

    Holzweber, Markus

    2013-01-01

    and components of strategy in Facility Management (FM). Since strategy refers to a complex network of thoughts, insights, experiences, expertise, and expectations that provide general guidance for management action, organizations must keep pace with the changing environment to increase market shares and business......Strategy implementation is critical for any type of organization. Strategy implementation is complex despite previous research describing mechanisms related to the construction of strategy and strategy use of organizations. In this article I attempt to fill this vacuity by examining strategy...... success. Based on a literature review, the findings of the study report a service-strategy classification grid. Such a service-strategy grid provides for a better understanding of the business environment. The study findings are intended to enhance business managers’ understandings of the issues behind FM...

  16. Effects of age on navigation strategy.

    Science.gov (United States)

    Rodgers, M Kirk; Sindone, Joseph A; Moffat, Scott D

    2012-01-01

    Age differences in navigation strategies have been demonstrated in animals, with aged animals more likely to prefer an egocentric (route) strategy and younger animals more likely to prefer an allocentric (place) strategy. Using a novel virtual Y-maze strategy assessment (vYSA), the present study demonstrated substantial age differences in strategy preference in humans. Older adults overwhelmingly preferred an egocentric strategy, while younger adults were equally distributed between egocentric and allocentric preference. A preference for allocentric strategy on the Y-maze strategy assessment was found to benefit performance on an independent assessment (virtual Morris water task) only in younger adults. These results establish baseline age differences in spatial strategies and suggest this may impact performance on other spatial navigation assessments. The results are interpreted within the framework of age differences in hippocampal structure and function. Copyright © 2012 Elsevier Inc. All rights reserved.

  17. An Energy Strategy for Canada

    Directory of Open Access Journals (Sweden)

    Michal C. Moore

    2015-10-01

    Full Text Available Canada is struggling to fully develop, sell and move its energy resources. This is a dramatic change from the recent past where the U.S. has provided stable growth in demand for energy supplied by the provinces, from hydrocarbons to electricity. Current circumstances now challenge this relationship, adding environmental, policy and economic hurdles that exacerbate the impact of fluctuations in world demand and pricing. In addition, competitive interaction between provinces, aboriginal land owners and special interest groups complicate and compound the issues of royalty returns, regulatory authority and direction, land-use management and long-term market opportunities for Canadian companies. There is no strategic document guiding the country’s energy future. As the steward of one of the largest, most diverse and valuable energy "banks" in the world, Canada has a unique opportunity to exploit a critical and valuable economic niche in the world economy. Given the lack of federal leadership and the tendency for each province to undercut each other in the same marketplace, there is also the distinct possibility the nation will squander the opportunity. This document offers the rationale for a comprehensive energy strategy, literally a vision where Canada can lead and not follow opportunities in energy markets. This strategic approach to energy systems by definition will include transportation, housing, employment and financial markets. It is not a plan, not a foil for tax or policy guidance in one or more sectors. This strategy is a fundamental rail on which plans, tactics and policies can be built. This vision identifies how the provinces can work together using all the tools available to them, maximizing long-term resource development while minimizing environmental damage. This document assumes there can be a broad commitment and effort by the federal government to help build those tools, providing guidance and assistance where needed without

  18. q-Strategy spatial prisoner's dilemma game

    International Nuclear Information System (INIS)

    Li, Zhi-Hua; Fan, Hong-Yi; Xu, Wen-Long; Yang, Han-Xin

    2011-01-01

    We generalize the usual two-strategy prisoner's dilemma game to a multi-strategy game, in which the strategy variable s is allowed to take q different fractional values lying between 0 and 1. The fractional-valued strategies signify that individuals are not absolutely cooperative or defective, instead they can adopt intermediate strategies. Simulation results on 1D and 2D lattices show that, compared with the binary strategy game, the multi-strategy game can sustain cooperation in more stringent defective environments. We give a comprehensive analysis of the distributions of the survived strategies and we compare pairwise the relative strength and weakness of different strategies. It turns out that some intermediate strategies survive the pure defection because they can reduce being exploited and at the same time benefit from the spatial reciprocity effect. Our work may shed some light on the intermediate behaviors in human society. -- Highlights: → We propose a q-strategy prisoner's dilemma game with intermediate strategies. → The intermediate strategies characterize the extent of cooperation or defection. → We implement the model in a structured population. → The intermediate strategies can promote cooperation.

  19. Toolbox of teaching strategies in nurse education

    Institute of Scientific and Technical Information of China (English)

    Jie-hui Xu

    2016-01-01

    There are a variety of teaching strategies that instructors can use to improve student learning. It is of great importance to select appropriate teaching strategies in nurse education to make the training more appealing and more effective. In this article, ten teaching strategies will be introduced to help instructors learn how to involve the teaching strategy in the nurse education. If using these strategies well, students are more likely to memorize the information associated with the lesson. Selection of teaching strategies appropriately is of great importance for nurse educators to deliver high-quality education.

  20. ANALISIS STRATEGI PENGEMBANGAN KAWASAN AGROPOLITAN KABUPATEN NGANJUK

    Directory of Open Access Journals (Sweden)

    Tripitono Adi Prabowo

    2015-10-01

    Full Text Available The aim in this study was to determine the development strategy of the region Agropolitan Nganjuk by knowing the internal factors and external factors that exist in Nganjuk. The method used in this research is SWOT analysis to identify the weaknesses, strengths, opportunities and challenges in the development of the area Agropolitan in Nganjuk so it can determine its development strategy. The results this study is the development strategy that can be used is divided into three stages: 1 Incubation, equating the vision of all stakeholders, 2 implementation, the implementation of development strategies that have been defined, 3 Exit Strategy, strategy development and renewal.