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Sample records for single mouse drag

  1. Tracking Human Immunodeficiency Virus-1 Infection in the Humanized DRAG Mouse Model

    Science.gov (United States)

    Kim, Jiae; Peachman, Kristina K.; Jobe, Ousman; Morrison, Elaine B.; Allam, Atef; Jagodzinski, Linda; Casares, Sofia A.; Rao, Mangala

    2017-01-01

    Humanized mice are emerging as an alternative model system to well-established non-human primate (NHP) models for studying human immunodeficiency virus (HIV)-1 biology and pathogenesis. Although both NHP and humanized mice have their own strengths and could never truly reflect the complex human immune system and biology, there are several advantages of using the humanized mice in terms of using primary HIV-1 for infection instead of simian immunodeficiency virus or chimera simian/HIV. Several different types of humanized mice have been developed with varying levels of reconstitution of human CD45+ cells. In this study, we utilized humanized Rag1KO.IL2RγcKO.NOD mice expressing HLA class II (DR4) molecule (DRAG mice) infused with HLA-matched hematopoietic stem cells from umbilical cord blood to study early events after HIV-1 infection, since the mucosal tissues of these mice are highly enriched for human lymphocytes and express the receptors and coreceptors needed for HIV-1 entry. We examined the various tissues on days 4, 7, 14, and 21 after an intravaginal administration of a single dose of purified primary HIV-1. Plasma HIV-1 RNA was detected as early as day 7, with 100% of the animals becoming plasma RNA positive by day 21 post-infection. Single cells were isolated from lymph nodes, bone marrow, spleen, gut, female reproductive tissue, and brain and analyzed for gag RNA and strong stop DNA by quantitative (RT)-PCR. Our data demonstrated the presence of HIV-1 viral RNA and DNA in all of the tissues examined and that the virus was replication competent and spread rapidly. Bone marrow, gut, and lymph nodes were viral RNA positive by day 4 post-infection, while other tissues and plasma became positive typically between 7 and 14 days post-infection. Interestingly, the brain was the last tissue to become HIV-1 viral RNA and DNA positive by day 21 post-infection. These data support the notion that humanized DRAG mice could serve as an excellent model for studying the

  2. Tracking Human Immunodeficiency Virus-1 Infection in the Humanized DRAG Mouse Model

    Directory of Open Access Journals (Sweden)

    Jiae Kim

    2017-10-01

    Full Text Available Humanized mice are emerging as an alternative model system to well-established non-human primate (NHP models for studying human immunodeficiency virus (HIV-1 biology and pathogenesis. Although both NHP and humanized mice have their own strengths and could never truly reflect the complex human immune system and biology, there are several advantages of using the humanized mice in terms of using primary HIV-1 for infection instead of simian immunodeficiency virus or chimera simian/HIV. Several different types of humanized mice have been developed with varying levels of reconstitution of human CD45+ cells. In this study, we utilized humanized Rag1KO.IL2RγcKO.NOD mice expressing HLA class II (DR4 molecule (DRAG mice infused with HLA-matched hematopoietic stem cells from umbilical cord blood to study early events after HIV-1 infection, since the mucosal tissues of these mice are highly enriched for human lymphocytes and express the receptors and coreceptors needed for HIV-1 entry. We examined the various tissues on days 4, 7, 14, and 21 after an intravaginal administration of a single dose of purified primary HIV-1. Plasma HIV-1 RNA was detected as early as day 7, with 100% of the animals becoming plasma RNA positive by day 21 post-infection. Single cells were isolated from lymph nodes, bone marrow, spleen, gut, female reproductive tissue, and brain and analyzed for gag RNA and strong stop DNA by quantitative (RT-PCR. Our data demonstrated the presence of HIV-1 viral RNA and DNA in all of the tissues examined and that the virus was replication competent and spread rapidly. Bone marrow, gut, and lymph nodes were viral RNA positive by day 4 post-infection, while other tissues and plasma became positive typically between 7 and 14 days post-infection. Interestingly, the brain was the last tissue to become HIV-1 viral RNA and DNA positive by day 21 post-infection. These data support the notion that humanized DRAG mice could serve as an excellent model

  3. Mouse manipulation through single-switch scanning.

    Science.gov (United States)

    Blackstien-Adler, Susie; Shein, Fraser; Quintal, Janet; Birch, Shae; Weiss, Patrice L Tamar

    2004-01-01

    Given the current extensive reliance on the graphical user interface, independent access to computer software requires that users be able to manipulate a pointing device of some type (e.g., mouse, trackball) or be able to emulate a mouse by some other means (e.g., scanning). The purpose of the present study was to identify one or more optimal single-switch scanning mouse emulation strategies. Four alternative scanning strategies (continuous Cartesian, discrete Cartesian, rotational, and hybrid quadrant/continuous Cartesian) were selected for testing based on current market availability as well as on theoretical considerations of their potential speed and accuracy. Each strategy was evaluated using a repeated measures study design by means of a test program that permitted mouse emulation via any one of four scanning strategies in a motivating environment; response speed and accuracy could be automatically recorded and considered in view of the motor, cognitive, and perceptual demands of each scanning strategy. Ten individuals whose disabilities required them to operate a computer via single-switch scanning participated in the study. Results indicated that Cartesian scanning was the preferred and most effective scanning strategy. There were no significant differences between results from the Continuous Cartesian and Discrete Cartesian scanning strategies. Rotational scanning was quite slow with respect to the other strategies, although it was equally accurate. Hybrid Quadrant scanning improved access time but at the cost of fewer correct selections. These results demonstrated the importance of testing and comparing alternate single-switch scanning strategies.

  4. Drag reduction by polymer addition in single and two-phase gas-liquid flows in pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Bizotto, Vanessa Cristina; Paes, Diogo Melo; Franca, Fernando de Almeida [Universidade Estadual de Campinas, SP (Brazil). Centro de Estudos de Petroleo. LabPetro]. E-mails: vanessa@cepetro.unicamp.br; diogopaes10@hotmail.com; Sabadini, Edvaldo [Universidade Estadual de Campinas, SP (Brazil). Inst. de Quimica]. E-mails: sabadini@iqm.unicamp.br; ffranca@fem.unicamp.br

    2008-07-01

    Turbulence mechanisms, as the eddies formation frequency and size, promote energy dissipation that appears as pressure drop in pipe flows. Adding minute amounts of polymers - ppm - of high molecular weight to the solution can lead to the reduction of the viscous dissipation. The formed macromolecules interact with the eddies, cause the eddies coherence breakdown, damp the energy transport and reduces the pressure drop. This phenomenon is known as the hydrodynamic drag reduction (DR, for short). Thus, for a given pipe flow rate there is decrease in pressure head, which is a desired operating strategy when transporting liquids. Studies on the hydrodynamic drag reduction in polymeric systems have been carried out in collaboration by the Chemistry Institute and the Petroleum Laboratory - LabPetro, UNICAMP. These studies have allowed microscopic approaches to the engineering scales, tackling the most usual processes - single phase flows, as well as gas-liquid two-phase flows in pipelines, which are quite common in the chemical and the petroleum industries. Tests conducted in the Chemistry Institute comprised over-the-bench experimentations made with a rotational double-gap type rheometer. These quick performed tests used small amount of polymers, and provided information on the additive concentration, the drag reduction and the solution mechanical stability along a turbulent shearing process. The results indicated that 17% is the limiting drag reduction achieved when a 2 ppm aqueous solution of polyacrylamide - PAM - was tested. These tests, besides giving preliminary estimations, are limited in terms of engineering application due to the low shearing rates applied by the viscometer. The tests performed at LabPetro comprised pressure drop measurements in actual pipe flows, both water single and air-water two-phase flows, using the previous knowledge acquired with the viscometer tests. In the former case, the Prandtl-von Karman map has been drawn to show the %DR in terms

  5. Assessing the use of immersive virtual reality, mouse and touchscreen in pointing and dragging-and-dropping tasks among young, middle-aged and older adults.

    Science.gov (United States)

    Chen, Jiayin; Or, Calvin

    2017-11-01

    This study assessed the use of an immersive virtual reality (VR), a mouse and a touchscreen for one-directional pointing, multi-directional pointing, and dragging-and-dropping tasks involving targets of smaller and larger widths by young (n = 18; 18-30 years), middle-aged (n = 18; 40-55 years) and older adults (n = 18; 65-75 years). A three-way, mixed-factorial design was used for data collection. The dependent variables were the movement time required and the error rate. Our main findings were that the participants took more time and made more errors in using the VR input interface than in using the mouse or the touchscreen. This pattern applied in all three age groups in all tasks, except for multi-directional pointing with a larger target width among the older group. Overall, older adults took longer to complete the tasks and made more errors than young or middle-aged adults. Larger target widths yielded shorter movement times and lower error rates in pointing tasks, but larger targets yielded higher rates of error in dragging-and-dropping tasks. Our study indicated that any other virtual environments that are similar to those we tested may be more suitable for displaying scenes than for manipulating objects that are small and require fine control. Although interacting with VR is relatively difficult, especially for older adults, there is still potential for older adults to adapt to that interface. Furthermore, adjusting the width of objects according to the type of manipulation required might be an effective way to promote performance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Absolute measurement of the total ion-drag force on a single plasma-confined microparticle at the void edge under microgravity conditions

    NARCIS (Netherlands)

    Beckers, J.; Trienekens, D.J.M.; Kroesen, G.M.W.

    2013-01-01

    We present an absolute measurement of the total ion-drag force on one single microparticle at the edge of the dust free region in low pressure complex plasmas: the void. In order to do so, the particle confinement position was monitored as a function of the gas pressure for two particle sizes under

  7. Growth of single crystalline seeds into polycrystalline strontium titanate: Anisotropy of the mobility, intrinsic drag effects and kinetic shape of grain boundaries

    International Nuclear Information System (INIS)

    Rheinheimer, Wolfgang; Bäurer, Michael; Handwerker, Carol A.; Blendell, John E.; Hoffmann, Michael J.

    2015-01-01

    We present a suite of measurements and combined analyses of grain growth in SrTiO 3 for oriented single crystals into polycrystals. The growth distance and standard deviation and the microstructure evolution along the single crystal–matrix interface are used to locally characterize the change in migration behavior as a function of temperature, time and interface orientation. The relative grain boundary mobility was determined between 1250 °C and 1600 °C for four crystallographic orientations {1 0 0}, {1 1 0}, {1 1 1} and {3 1 0}. An absolute mobility of these orientations is estimated. Under fast growth conditions the morphology of single crystals shows macroscopic stepping with parts of the interface rotating to low mobility orientations. This effect represents a kinetic influence on the grain boundary morphology. The results also indicate dragging effects on microstructure coarsening, which indicate the existence of a critical driving force for grain growth. This critical driving force seems to be related to an ‘intrinsic’ interface drag similar to the solute drag, but based on intrinsic defects. At 1460 °C the growth of single crystals was significantly faster than expected from the mobility of the polycrystal and was identified as exaggerated grain growth. The findings give new insights into the recently published grain growth anomaly of strontium titanate, leading to a hypothesis based on the temperature dependent relative mobility of {1 0 0} oriented grain boundaries

  8. Mouse SNP Miner: an annotated database of mouse functional single nucleotide polymorphisms

    Directory of Open Access Journals (Sweden)

    Ramensky Vasily E

    2007-01-01

    Full Text Available Abstract Background The mapping of quantitative trait loci in rat and mouse has been extremely successful in identifying chromosomal regions associated with human disease-related phenotypes. However, identifying the specific phenotype-causing DNA sequence variations within a quantitative trait locus has been much more difficult. The recent availability of genomic sequence from several mouse inbred strains (including C57BL/6J, 129X1/SvJ, 129S1/SvImJ, A/J, and DBA/2J has made it possible to catalog DNA sequence differences within a quantitative trait locus derived from crosses between these strains. However, even for well-defined quantitative trait loci ( Description To help identify functional DNA sequence variations within quantitative trait loci we have used the Ensembl annotated genome sequence to compile a database of mouse single nucleotide polymorphisms (SNPs that are predicted to cause missense, nonsense, frameshift, or splice site mutations (available at http://bioinfo.embl.it/SnpApplet/. For missense mutations we have used the PolyPhen and PANTHER algorithms to predict whether amino acid changes are likely to disrupt protein function. Conclusion We have developed a database of mouse SNPs predicted to cause missense, nonsense, frameshift, and splice-site mutations. Our analysis revealed that 20% and 14% of missense SNPs are likely to be deleterious according to PolyPhen and PANTHER, respectively, and 6% are considered deleterious by both algorithms. The database also provides gene expression and functional annotations from the Symatlas, Gene Ontology, and OMIM databases to further assess candidate phenotype-causing mutations. To demonstrate its utility, we show that Mouse SNP Miner successfully finds a previously identified candidate SNP in the taste receptor, Tas1r3, that underlies sucrose preference in the C57BL/6J strain. We also use Mouse SNP Miner to derive a list of candidate phenotype-causing mutations within a previously

  9. Single-mass mutations associated with mouse lymphomas

    International Nuclear Information System (INIS)

    Guerrero, I.; Berman, J.W.; Diamond, L.E.; Newcomb, E.W.; Villasante, A.

    1986-01-01

    The authors study the induction of mouse lymphomas after treatment with a chemical carcinogen, nitrosomethyl urea (NMU), or with gamma irradiation. The koplan fractionated gamma radiation scheme and an established protocol for NMU tumor formation were chosen as protocols for induction of mouse lymphomas. In both cases, the mice developed thymic lymphomas with up to 90% incidence. In NMU induction, the latency period is shorter than irradiation

  10. Studies of Aerodynamic Drag.

    Science.gov (United States)

    1982-12-01

    31. Strouhal number vs Reynolds number - Effect of Wind tunnel Blockage. 150- P ecrit 100- 50k- o present d Qta o Mitry (1977) --Shair et ati (1963) 0...forces measured by the balance. 4.12 Final Tests A comprehensive set of drag measurements was taken with the new drag plates, the drag plates being

  11. Developmental fate and lineage commitment of singled mouse blastomeres.

    Science.gov (United States)

    Lorthongpanich, Chanchao; Doris, Tham Puay Yoke; Limviphuvadh, Vachiranee; Knowles, Barbara B; Solter, Davor

    2012-10-01

    The inside-outside model has been invoked to explain cell-fate specification of the pre-implantation mammalian embryo. Here, we investigate whether cell-cell interaction can influence the fate specification of embryonic blastomeres by sequentially separating the blastomeres in two-cell stage mouse embryos and continuing separation after each cell division throughout pre-implantation development. This procedure eliminates information provided by cell-cell interaction and cell positioning. Gene expression profiles, polarity protein localization and functional tests of these separated blastomeres reveal that cell interactions, through cell position, influence the fate of the blastomere. Blastomeres, in the absence of cell contact and inner-outer positional information, have a unique pattern of gene expression that is characteristic of neither inner cell mass nor trophectoderm, but overall they have a tendency towards a 'trophectoderm-like' gene expression pattern and preferentially contribute to the trophectoderm lineage.

  12. Isolation of Kupffer Cells and Hepatocytes from a Single Mouse Liver

    DEFF Research Database (Denmark)

    Aparicio-Vergara, Marcela; Tencerova, Michaela; Morgantini, Cecilia

    2017-01-01

    Liver perfusion is a common technique used to isolate parenchymal and non-parenchymal liver cells for in vitro experiments. This method allows hepatic cells to be separated based on their size and weight, by centrifugation using a density gradient. To date, other methods allow the isolation of only...... one viable hepatic cellular fraction from a single mouse; either parenchymal (hepatocytes) or non-parenchymal cells (i.e., Kupffer cells or hepatic stellate cells). Here, we describe a method to isolate both hepatocytes and Kupffer cells from a single mouse liver, thereby providing the unique...... advantage of studying different liver cell types that have been isolated from the same organism....

  13. Symmetry breaking for drag minimization

    Science.gov (United States)

    Roper, Marcus; Squires, Todd M.; Brenner, Michael P.

    2005-11-01

    For locomotion at high Reynolds numbers drag minimization favors fore-aft asymmetric slender shapes with blunt noses and sharp trailing edges. On the other hand, in an inertialess fluid the drag experienced by a body is independent of whether it travels forward or backward through the fluid, so there is no advantage to having a single preferred swimming direction. In fact numerically determined minimum drag shapes are known to exhibit almost no fore-aft asymmetry even at moderate Re. We show that asymmetry persists, albeit extremely weakly, down to vanishingly small Re, scaling asymptotically as Re^3. The need to minimize drag to maximize speed for a given propulsive capacity gives one possible mechanism for the increasing asymmetry in the body plans seen in nature, as organisms increase in size and swimming speed from bacteria like E-Coli up to pursuit predator fish such as tuna. If it is the dominant mechanism, then this signature scaling will be observed in the shapes of motile micro-organisms.

  14. Racializing white drag.

    Science.gov (United States)

    Rhyne, Ragan

    2004-01-01

    While drag is primarily understood as a performance of gender, other performative categories such as race, class, and sexuality create drag meaning as well. Though other categories of identification are increasingly understood as essential elements of drag by performers of color, whiteness remains an unmarked category in the scholarship on drag performances by white queens. In this paper, I argue that drag by white queens must be understood as a performance of race as well as gender and that codes of gender excess are specifically constructed through the framework of these other axes of identity. This essay asks whether white performance by white queens necessarily reinscribes white supremacy through the performance of an unmarked white femininity, or might drag performance complicate (though not necessarily subvert) categories of race as well as gender? In this essay, I will suggest that camp drag performances, through the deployment of class as a crucial category of performative femininity, might indeed be a key site through which whiteness is denaturalized and its power challenged. Specifically, I will read on camp as a politicized mode of race, class and gender performance, focusing on the intersections of these categories of identity in the drag performance of Divine.

  15. Pipeline Drag Reducers

    International Nuclear Information System (INIS)

    Marawan, H.

    2004-01-01

    Pipeline drag reducers have proven to be an extremely powerful tool in fluid transportation. High molecular weight polymers are used to reduce the frictional pressure loss ratio in crude oil pipelines, refined fuel and aqueous pipelines. Chemical structure of the main used pipeline drag reducers is one of the following polymers and copolymers classified according to the type of fluid to ; low density polyethylene, copolymer of I-hexane cross linked with divinyl benzene, polyacrylamide, polyalkylene oxide polymers and their copolymers, fluorocarbons, polyalkyl methacrylates and terpolymer of styrene, alkyl acrylate and acrylic acid. Drag reduction is the increase in pump ability of a fluid caused by the addition of small amounts of an additive to the fluid. The effectiveness of a drag reducer is normally expressed in terms of percent drag reduction. Frictional pressure loss in a pipeline system is a waste of energy and it costly. The drag reducing additive minimizes the flow turbulence, increases throughput and reduces the energy costs. The Flow can be increased by more than 80 % with existing assets. The effectiveness of the injected drag reducer in Mostorod to Tanta crude oil pipeline achieved 35.4 % drag reduction and 23.2 % flow increase of the actual performance The experimental application of DRA on Arab Petroleum Pipeline Company (Summed) achieved a flow increase ranging from 9-32 %

  16. A comparison of muscular activity during single and double mouse clicks.

    Science.gov (United States)

    Thorn, Stefan; Forsman, Mikael; Hallbeck, Susan

    2005-05-01

    Work-related musculoskeletal disorders (WMSDs) in the neck/shoulder region and the upper extremities are a common problem among computer workers. Occurrences of motor unit (MU) double discharges with very short inter-firing intervals (doublets) have been hypothesised as a potential additional risk for overuse of already exhausted fibres during long-term stereotyped activity. Doublets are reported to be present during double-click mouse work tasks. A few comparative studies have been carried out on overall muscle activities for short-term tasks with single types of actions, but none on occurrences of doublets during double versus single clicks. The main purpose of this study was to compare muscle activity levels of single and double mouse clicks during a long-term combined mouse/keyboard work task. Four muscles were studied: left and right upper trapezius, right extensor digitorum communis (EDC) and right flexor carpi ulnaris. Additionally, MU activity was analysed through intramuscular electromyography in the EDC muscle for a selection of subjects. The results indicate that double clicking produces neither higher median or 90th percentile levels in the trapezius and EDC muscles, nor a higher disposition for MU doublets, than does single clicking. Especially for the 90th percentile levels, the indications are rather the opposite (in the EDC significantly higher during single clicks in 8 of 11 subjects, P < 0.05). Although it cannot be concluded from the present study that double clicks are harmless, there were no signs that double clicks during computer work generally constitute a larger risk factor for WMSDs than do single clicks.

  17. Air Layer Drag Reduction

    Science.gov (United States)

    Ceccio, Steven; Elbing, Brian; Winkel, Eric; Dowling, David; Perlin, Marc

    2008-11-01

    A set of experiments have been conducted at the US Navy's Large Cavitation Channel to investigate skin-friction drag reduction with the injection of air into a high Reynolds number turbulent boundary layer. Testing was performed on a 12.9 m long flat-plate test model with the surface hydraulically smooth and fully rough at downstream-distance-based Reynolds numbers to 220 million and at speeds to 20 m/s. Local skin-friction, near-wall bulk void fraction, and near-wall bubble imaging were monitored along the length of the model. The instrument suite was used to access the requirements necessary to achieve air layer drag reduction (ALDR). Injection of air over a wide range of air fluxes showed that three drag reduction regimes exist when injecting air; (1) bubble drag reduction that has poor downstream persistence, (2) a transitional regime with a steep rise in drag reduction, and (3) ALDR regime where the drag reduction plateaus at 90% ± 10% over the entire model length with large void fractions in the near-wall region. These investigations revealed several requirements for ALDR including; sufficient volumetric air fluxes that increase approximately with the square of the free-stream speed, slightly higher air fluxes are needed when the surface tension is reduced, higher air fluxes are required for rough surfaces, and the formation of ALDR is sensitive to the inlet condition.

  18. Dissecting Transcriptional Heterogeneity in Pluripotency: Single Cell Analysis of Mouse Embryonic Stem Cells.

    Science.gov (United States)

    Guedes, Ana M V; Henrique, Domingos; Abranches, Elsa

    2016-01-01

    Mouse Embryonic Stem cells (mESCs) show heterogeneous and dynamic expression of important pluripotency regulatory factors. Single-cell analysis has revealed the existence of cell-to-cell variability in the expression of individual genes in mESCs. Understanding how these heterogeneities are regulated and what their functional consequences are is crucial to obtain a more comprehensive view of the pluripotent state.In this chapter we describe how to analyze transcriptional heterogeneity by monitoring gene expression of Nanog, Oct4, and Sox2, using single-molecule RNA FISH in single mESCs grown in different cell culture medium. We describe in detail all the steps involved in the protocol, from RNA detection to image acquisition and processing, as well as exploratory data analysis.

  19. Active aerodynamic drag reduction on morphable cylinders

    Science.gov (United States)

    Guttag, M.; Reis, P. M.

    2017-12-01

    We study a mechanism for active aerodynamic drag reduction on morphable grooved cylinders, whose topography can be modified pneumatically. Our design is inspired by the morphology of the Saguaro cactus (Carnegiea gigantea), which possesses an array of axial grooves, thought to help reduce aerodynamic drag, thereby enhancing the structural robustness of the plant under wind loading. Our analog experimental samples comprise a spoked rigid skeleton with axial cavities, covered by a stretched elastomeric film. Decreasing the inner pressure of the sample produces axial grooves, whose depth can be accurately varied, on demand. First, we characterize the relation between groove depth and pneumatic loading through a combination of precision mechanical experiments and finite element simulations. Second, wind tunnel tests are used to measure the aerodynamic drag coefficient (as a function of Reynolds number) of the grooved samples, with different levels of periodicity and groove depths. We focus specifically on the drag crisis and systematically measure the associated minimum drag coefficient and the critical Reynolds number at which it occurs. The results are in agreement with the classic literature of rough cylinders, albeit with an unprecedented level of precision and resolution in varying topography using a single sample. Finally, we leverage the morphable nature of our system to dynamically reduce drag for varying aerodynamic loading conditions. We demonstrate that actively controlling the groove depth yields a drag coefficient that decreases monotonically with Reynolds number and is significantly lower than the fixed sample counterparts. These findings open the possibility for the drag reduction of grooved cylinders to be operated over a wide range of flow conditions.

  20. Aerodynamic Drag Scoping Work.

    Energy Technology Data Exchange (ETDEWEB)

    Voskuilen, Tyler [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Erickson, Lindsay Crowl [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Knaus, Robert C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2018-02-01

    This memo summarizes the aerodynamic drag scoping work done for Goodyear in early FY18. The work is to evaluate the feasibility of using Sierra/Low-Mach (Fuego) for drag predictions of rolling tires, particularly focused on the effects of tire features such as lettering, sidewall geometry, rim geometry, and interaction with the vehicle body. The work is broken into two parts. Part 1 consisted of investigation of a canonical validation problem (turbulent flow over a cylinder) using existing tools with different meshes and turbulence models. Part 2 involved calculating drag differences over plate geometries with simple features (ridges and grooves) defined by Goodyear of approximately the size of interest for a tire. The results of part 1 show the level of noise to be expected in a drag calculation and highlight the sensitivity of absolute predictions to model parameters such as mesh size and turbulence model. There is 20-30% noise in the experimental measurements on the canonical cylinder problem, and a similar level of variation between different meshes and turbulence models. Part 2 shows that there is a notable difference in the predicted drag on the sample plate geometries, however, the computational cost of extending the LES model to a full tire would be significant. This cost could be reduced by implementation of more sophisticated wall and turbulence models (e.g. detached eddy simulations - DES) and by focusing the mesh refinement on feature subsets with the goal of comparing configurations rather than absolute predictivity for the whole tire.

  1. Effect of BCNU on mouse skin and spinal cord in single drug and radiation exposures

    International Nuclear Information System (INIS)

    Lelieveld, P.; Brown, J.M.; Goffinet, D.R.; Schoeppel, S.L.; Scoles, M.

    1979-01-01

    We set out to determine whether any interaction occurs between BCNU and radiation for the mouse skin and spinal cord. Single doses of BCNU of 10, 20, or 30 mg/kg were injected intraperitoneally as a function of time before or after irradiation of the foot or spinal cord of anesthesized C3H mice. Enhancement of the radiation skin reaction (dose enhancement factor = 1.3) was seen when BCNU (30 mg/kg) was given 1 day, 6 hr, and 2 hr prior to irradiation of the foot with 2,500 rad, and a larger DEF of 1.6 was observed when BCNU was given immediately before the radiation dose. However, with a different mouse strain (BALB/c) not anesthetized at the time of irradiation, no significant enhancement following a dose of 20 mg/kg BCNU was observed. Experiments are in progress to determine the cause of these differences. BCNU (10 mg/kg) was given 24 hr or immediately prior to various single doses of radiation to a 12 mm segment of the mouse spinal cord (T/sub 11-12/ to L/sub 1-2/), and the subsequent myelitis was scored monthly. The addition of BCNU to irradiation did not accelerate the development of myelitis, not the ultimate proportion of animals developing hind limb paralysis: the 50% myelitis dose at 10 months (MD/sub 50/10/sub mo/) values for irradiation alone, BCNU at the time of irradiation and 24 hr before were 3,722, 3,795 and 3,853 rad, respectively

  2. Cryo-imaging of fluorescently labeled single cells in a mouse

    Science.gov (United States)

    Steyer, Grant J.; Roy, Debashish; Salvado, Olivier; Stone, Meredith E.; Wilson, David L.

    2009-02-01

    We developed a cryo-imaging system to provide single-cell detection of fluorescently labeled cells in mouse, with particular applicability to stem cells and metastatic cancer. The Case cryoimaging system consists of a fluorescence microscope, robotic imaging positioner, customized cryostat, PC-based control system, and visualization/analysis software. The system alternates between sectioning (10-40 μm) and imaging, collecting color brightfield and fluorescent blockface image volumes >60GB. In mouse experiments, we imaged quantum-dot labeled stem cells, GFP-labeled cancer and stem cells, and cell-size fluorescent microspheres. To remove subsurface fluorescence, we used a simplified model of light-tissue interaction whereby the next image was scaled, blurred, and subtracted from the current image. We estimated scaling and blurring parameters by minimizing entropy of subtracted images. Tissue specific attenuation parameters were found [uT : heart (267 +/- 47.6 μm), liver (218 +/- 27.1 μm), brain (161 +/- 27.4 μm)] to be within the range of estimates in the literature. "Next image" processing removed subsurface fluorescence equally well across multiple tissues (brain, kidney, liver, adipose tissue, etc.), and analysis of 200 microsphere images in the brain gave 97+/-2% reduction of subsurface fluorescence. Fluorescent signals were determined to arise from single cells based upon geometric and integrated intensity measurements. Next image processing greatly improved axial resolution, enabled high quality 3D volume renderings, and improved enumeration of single cells with connected component analysis by up to 24%. Analysis of image volumes identified metastatic cancer sites, found homing of stem cells to injury sites, and showed microsphere distribution correlated with blood flow patterns. We developed and evaluated cryo-imaging to provide single-cell detection of fluorescently labeled cells in mouse. Our cryo-imaging system provides extreme (>60GB), micron

  3. Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation

    Directory of Open Access Journals (Sweden)

    Zhao Roong

    2001-12-01

    Full Text Available Abstract Background Transgenic mice have been used extensively to analyze gene function. Unfortunately, traditional transgenic procedures have only limited use in analyzing alleles that cause lethality because lines of founder mice cannot be established. This is frustrating given that such alleles often reveal crucial aspects of gene function. For this reason techniques that facilitate the generation of embryos expressing such alleles would be of enormous benefit. Although the transient generation of transgenic embryos has allowed limited analysis of lethal alleles, it is expensive, time consuming and technically challenging. Moreover a fundamental limitation with this approach is that each embryo generated is unique and transgene expression is highly variable due to the integration of different transgene copy numbers at random genomic sites. Results Here we describe an alternative method that allows the generation of clonal mouse embryos harboring a single-copy transgene at a defined genomic location. This was facilitated through the production of Hprt negative embryonic stem cells that allow the derivation of embryos by tetraploid embryo complementation. We show that targeting transgenes to the hprt locus in these ES cells by homologous recombination can be efficiently selected by growth in HAT medium. Moreover, embryos derived solely from targeted ES cells containing a single copy LacZ transgene under the control of the α-myosin heavy chain promoter exhibited the expected cardiac specific expression pattern. Conclusion Our results demonstrate that tetraploid embryo complementation by F3 hprt negative ES cells facilitates the generation of transgenic mouse embryos containing a single copy gene at a defined genomic locus. This approach is simple, extremely efficient and bypasses any requirement to generate chimeric mice. Moreover embryos generated by this procedure are clonal in that they are all derived from a single ES cell lines. This

  4. Magnon-drag thermopile.

    Science.gov (United States)

    Costache, Marius V; Bridoux, German; Neumann, Ingmar; Valenzuela, Sergio O

    2011-12-18

    Thermoelectric effects in spintronics are gathering increasing attention as a means of managing heat in nanoscale structures and of controlling spin information by using heat flow. Thermal magnons (spin-wave quanta) are expected to play a major role; however, little is known about the underlying physical mechanisms involved. The reason is the lack of information about magnon interactions and of reliable methods to obtain it, in particular for electrical conductors because of the intricate influence of electrons. Here, we demonstrate a conceptually new device that enables us to gather information on magnon-electron scattering and magnon-drag effects. The device resembles a thermopile formed by a large number of pairs of ferromagnetic wires placed between a hot and a cold source and connected thermally in parallel and electrically in series. By controlling the relative orientation of the magnetization in pairs of wires, the magnon drag can be studied independently of the electron and phonon-drag thermoelectric effects. Measurements as a function of temperature reveal the effect on magnon drag following a variation of magnon and phonon populations. This information is crucial to understand the physics of electron-magnon interactions, magnon dynamics and thermal spin transport.

  5. Grafting of a Single Donor Myofibre Promotes Hypertrophy in Dystrophic Mouse Muscle

    Science.gov (United States)

    Boldrin, Luisa; Morgan, Jennifer E.

    2013-01-01

    Skeletal muscle has a remarkable capability of regeneration following injury. Satellite cells, the principal muscle stem cells, are responsible for this process. However, this regenerative capacity is reduced in muscular dystrophies or in old age: in both these situations, there is a net loss of muscle fibres. Promoting skeletal muscle muscle hypertrophy could therefore have potential applications for treating muscular dystrophies or sarcopenia. Here, we observed that muscles of dystrophic mdx nude host mice that had been acutely injured by myotoxin and grafted with a single myofibre derived from a normal donor mouse exhibited increased muscle area. Transplantation experiments revealed that the hypertrophic effect is mediated by the grafted fibre and does not require either an imposed injury to the host muscle, or the contribution of donor cells to the host muscle. These results suggest the presence of a crucial cross-talk between the donor fibre and the host muscle environment. PMID:23349935

  6. Single-Step Generation of Conditional Knockout Mouse Embryonic Stem Cells

    Directory of Open Access Journals (Sweden)

    Matyas Flemr

    2015-07-01

    Full Text Available Induction of double-strand DNA breaks (DSBs by engineered nucleases, such as CRISPR/Cas9 or transcription activator-like effector nucleases (TALENs, stimulates knockin of exogenous DNA fragments via homologous recombination (HR. However, the knockin efficiencies reported so far have not allowed more complex in vitro genome modifications such as, for instance, simultaneous integration of a DNA fragment at two distinct genomic sites. We developed a reporter system to enrich for cells with engineered nuclease-assisted HR events. Using this system in mouse embryonic stem cells (mESCs, we achieve single-step biallelic and seamless integration of two loxP sites for Cre recombinase-mediated inducible gene knockout, as well as biallelic endogenous gene tagging with high efficiency. Our approach reduces the time and resources required for conditional knockout mESC generation dramatically.

  7. Subcellular distribution of glycogen and decreased tetanic Ca2+ in fatigued single intact mouse muscle fibres

    DEFF Research Database (Denmark)

    Nielsen, Joachim; Cheng, Arthur J; Ørtenblad, Niels

    2014-01-01

    In skeletal muscle fibres, glycogen has been shown to be stored at different subcellular locations: (i) between the myofibrils (intermyofibrillar); (ii) within the myofibrils (intramyofibrillar); and (iii) subsarcolemmal. Of these, intramyofibrillar glycogen has been implied as a critical regulator...... of sarcoplasmic reticulum Ca(2+) release. The aim of the present study was to test directly how the decrease in cytoplasmic free Ca(2+) ([Ca(2+)]i) during repeated tetanic contractions relates to the subcellular glycogen distribution. Single fibres of mouse flexor digitorum brevis muscles were fatigued with 70 Hz...... in tetanic [Ca(2+)]i, and hence force, is accompanied by major reductions in inter- and intramyofibrillar glycogen. The stronger correlation between decreased tetanic [Ca(2+)]i and reduced intramyofibrillar glycogen implies that sarcoplasmic reticulum Ca(2+) release critically depends on energy supply from...

  8. Dragging of inertial frames.

    Science.gov (United States)

    Ciufolini, Ignazio

    2007-09-06

    The origin of inertia has intrigued scientists and philosophers for centuries. Inertial frames of reference permeate our daily life. The inertial and centrifugal forces, such as the pull and push that we feel when our vehicle accelerates, brakes and turns, arise because of changes in velocity relative to uniformly moving inertial frames. A classical interpretation ascribed these forces to acceleration relative to some absolute frame independent of the cosmological matter, whereas an opposite view related them to acceleration relative to all the masses and 'fixed stars' in the Universe. An echo and partial realization of the latter idea can be found in Einstein's general theory of relativity, which predicts that a spinning mass will 'drag' inertial frames along with it. Here I review the recent measurements of frame dragging using satellites orbiting Earth.

  9. Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo.

    Science.gov (United States)

    De Silva, Samantha R; Charbel Issa, Peter; Singh, Mandeep S; Lipinski, Daniel M; Barnea-Cramer, Alona O; Walker, Nathan J; Barnard, Alun R; Hankins, Mark W; MacLaren, Robert E

    2016-11-01

    Gene therapy using adeno-associated viral (AAV) vectors for the treatment of retinal degenerations has shown safety and efficacy in clinical trials. However, very high levels of vector expression may be necessary for the treatment of conditions such as Stargardt disease where a dual vector approach is potentially needed, or in optogenetic strategies for end-stage degeneration in order to achieve maximal light sensitivity. In this study, we assessed two vectors with single capsid mutations, rAAV2/2(Y444F) and rAAV2/8(Y733F) in their ability to transduce retina in the Abca4 -/- and rd1 mouse models of retinal degeneration. We noted significantly increased photoreceptor transduction using rAAV2/8(Y733F) in the Abca4 -/- mouse, in contrast to previous work where vectors tested in this model have shown low levels of photoreceptor transduction. Bipolar cell transduction was achieved following subretinal delivery of both vectors in the rd1 mouse, and via intravitreal delivery of rAAV2/2(Y444F). The successful use of rAAV2/8(Y733F) to target bipolar cells was further validated on human tissue using an ex vivo culture system of retinal explants. Capsid mutant AAV vectors transduce human retinal cells and may be particularly suited to treat retinal degenerations in which high levels of transgene expression are required.

  10. Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

    Directory of Open Access Journals (Sweden)

    Hisham Mohammed

    2017-08-01

    Full Text Available The mouse inner cell mass (ICM segregates into the epiblast and primitive endoderm (PrE lineages coincident with implantation of the embryo. The epiblast subsequently undergoes considerable expansion of cell numbers prior to gastrulation. To investigate underlying regulatory principles, we performed systematic single-cell RNA sequencing (seq of conceptuses from E3.5 to E6.5. The epiblast shows reactivation and subsequent inactivation of the X chromosome, with Zfp57 expression associated with reactivation and inactivation together with other candidate regulators. At E6.5, the transition from epiblast to primitive streak is linked with decreased expression of polycomb subunits, suggesting a key regulatory role. Notably, our analyses suggest elevated transcriptional noise at E3.5 and within the non-committed epiblast at E6.5, coinciding with exit from pluripotency. By contrast, E6.5 primitive streak cells became highly synchronized and exhibit a shortened G1 cell-cycle phase, consistent with accelerated proliferation. Our study systematically charts transcriptional noise and uncovers molecular processes associated with early lineage decisions.

  11. Chemical Cocktails Enable Hepatic Reprogramming of Mouse Fibroblasts with a Single Transcription Factor

    Directory of Open Access Journals (Sweden)

    Ren Guo

    2017-08-01

    Full Text Available Liver or hepatocytes transplantation is limited by the availability of donor organs. Functional hepatocytes independent of the donor sources may have wide applications in regenerative medicine and the drug industry. Recent studies have demonstrated that chemical cocktails may induce reprogramming of fibroblasts into a range of functional somatic cells. Here, we show that mouse fibroblasts can be transdifferentiated into the hepatocyte-like cells (iHeps using only one transcription factor (TF (Foxa1, Foxa2, or Foxa3 plus a chemical cocktail. These iHeps show typical epithelial morphology, express multiple hepatocyte-specific genes, and acquire hepatocyte functions. Genetic lineage tracing confirms the fibroblast origin of these iHeps. More interestingly, these iHeps are expandable in vitro and can reconstitute the damaged hepatic tissues of the fumarylacetoacetate hydrolase-deficient (Fah−/− mice. Our study provides a strategy to generate functional hepatocyte-like cells by using a single TF plus a chemical cocktail and is one step closer to generate the full-chemical iHeps.

  12. Accelerated repopulation of mouse tongue epithelium during fractionated irradiations or following single doses

    International Nuclear Information System (INIS)

    Doerr, W.; Kummermehr, J.

    1990-01-01

    Mouse tongue mucosa was established as an animal model to study repopulation after large single doses or during continuous irradiation. A top-up irradiation technique was used employing priming doses or fractionated treatment to the whole snout (300 kV X-rays) followed by local test doses (25 kV X-rays) to elicit denudation in a confined field of the inferior tongue surface. Clearcut quantal dose-response curves of ulcer incidence were obtained to all protocols; animal morbidity, i.e. body weight loss was minimal. Repopulation following priming doses of 10 and 13 Gy started with a delay of at least 3 days and then progressed rapidly to nearly restore original tissue tolerance by day 11. During continuous fractionation over 1 to 3 weeks with 5 fractions/week and doses per fraction of 2.5, 3 and 3.5 Gy, repopulation was small in week one but subsequently increased to fully compensate the weekly dose at all dose levels. Additional measurements of cell density during a 4 weeks course of 5 x 3 Gy or 5 x 4 Gy per week showed only moderate depletion to 67% of the control figures. The fact that rapid repopulation is achieved at relatively moderate damage levels should be taken into account when the timing of a treatment split is considered. (author). 18 refs.; 7 figs.; 1 tab

  13. Generation of organized germ layers from a single mouse embryonic stem cell.

    Science.gov (United States)

    Poh, Yeh-Chuin; Chen, Junwei; Hong, Ying; Yi, Haiying; Zhang, Shuang; Chen, Junjian; Wu, Douglas C; Wang, Lili; Jia, Qiong; Singh, Rishi; Yao, Wenting; Tan, Youhua; Tajik, Arash; Tanaka, Tetsuya S; Wang, Ning

    2014-05-30

    Mammalian inner cell mass cells undergo lineage-specific differentiation into germ layers of endoderm, mesoderm and ectoderm during gastrulation. It has been a long-standing challenge in developmental biology to replicate these organized germ layer patterns in culture. Here we present a method of generating organized germ layers from a single mouse embryonic stem cell cultured in a soft fibrin matrix. Spatial organization of germ layers is regulated by cortical tension of the colony, matrix dimensionality and softness, and cell-cell adhesion. Remarkably, anchorage of the embryoid colony from the 3D matrix to collagen-1-coated 2D substrates of ~1 kPa results in self-organization of all three germ layers: ectoderm on the outside layer, mesoderm in the middle and endoderm at the centre of the colony, reminiscent of generalized gastrulating chordate embryos. These results suggest that mechanical forces via cell-matrix and cell-cell interactions are crucial in spatial organization of germ layers during mammalian gastrulation. This new in vitro method could be used to gain insights on the mechanisms responsible for the regulation of germ layer formation.

  14. Molecular hierarchy in neurons differentiated from mouse ES cells containing a single human chromosome 21.

    Science.gov (United States)

    Wang, Chi Chiu; Kadota, Mitsutaka; Nishigaki, Ryuichi; Kazuki, Yasuhiro; Shirayoshi, Yasuaki; Rogers, Michael Scott; Gojobori, Takashi; Ikeo, Kazuho; Oshimura, Mitsuo

    2004-02-06

    Defects in neurogenesis and neuronal differentiation in the fetal brain of Down syndrome (DS) patients lead to the apparent neuropathological abnormalities and contribute to the phenotypic characters of mental retardation, and premature development of Alzheimer's disease, those being the most common phenotype in DS. In order to understand the molecular mechanism underlying the cause of phenotypic abnormalities in the DS brain, we have utilized an in vitro model of TT2F mouse embryonic stem cells containing a single human chromosome 21 (hChr21) to study neuron development and neuronal differentiation by microarray containing 15K developmentally expressed cDNAs. Defective neuronal differentiation in the presence of extra hChr21 manifested primarily the post-transcriptional and translational modification, such as Mrpl10, SNAPC3, Srprb, SF3a60 in the early neuronal stem cell stage, and Mrps18a, Eef1g, and Ubce8 in the late differentiated stage. Hierarchical clustering patterned specific expression of hChr21 gene dosage effects on neuron outgrowth, migration, and differentiation, such as Syngr2, Dncic2, Eif3sf, and Peg3.

  15. Design and Generation of Humanized Single-chain Fv Derived from Mouse Hybridoma for Potential Targeting Application.

    Science.gov (United States)

    Khantasup, Kannika; Chantima, Warangkana; Sangma, Chak; Poomputsa, Kanokwan; Dharakul, Tararaj

    2015-12-01

    Single-chain variable antibody fragments (scFvs) are attractive candidates for targeted immunotherapy in several human diseases. In this study, a concise humanization strategy combined with an optimized production method for humanizing scFvs was successfully employed. Two antibody clones, one directed against the hemagglutinin of H5N1 influenza virus, the other against EpCAM, a cancer biomarker, were used to demonstrate the validity of the method. Heavy chain (VH) and light chain (VL) variable regions of immunoglobulin genes from mouse hybridoma cells were sequenced and subjected to the construction of mouse scFv 3-D structure. Based on in silico modeling, the humanized version of the scFv was designed via complementarity-determining region (CDR) grafting with the retention of mouse framework region (FR) residues identified by primary sequence analysis. Root-mean-square deviation (RMSD) value between mouse and humanized scFv structures was calculated to evaluate the preservation of CDR conformation. Mouse and humanized scFv genes were then constructed and expressed in Escherichia coli. Using this method, we successfully generated humanized scFvs that retained the targeting activity of their respective mouse scFv counterparts. In addition, the humanized scFvs were engineered with a C-terminal cysteine residue (hscFv-C) for site-directed conjugation for use in future targeting applications. The hscFv-C expression was extensively optimized to improve protein production yield. The protocol yielded a 20-fold increase in production of hscFv-Cs in E. coli periplasm. The strategy described in this study may be applicable in the humanization of other antibodies derived from mouse hybridoma.

  16. Graft function assessment in mouse models of single- and dual- kidney transplantation.

    Science.gov (United States)

    Wang, Lei; Wang, Ximing; Jiang, Shan; Wei, Jin; Buggs, Jacentha; Fu, Liying; Zhang, Jie; Liu, Ruisheng

    2018-05-23

    Animal models of kidney transplantation (KTX) are widely used in studying immune response of hosts to implanted grafts. Additionally, KTX can be used in generating kidney-specific knockout animal models by transplantation of kidneys from donors with global knockout of a gene to wild type recipients or vise verse. Dual kidney transplantation (DKT) provides a more physiological environment for recipients than single kidney transplantation (SKT). However, DKT in mice is rare due to technical challenges. In this study, we successfully performed DKT in mice and compared the hemodynamic response and graft function with SKT. The surgical time, complications and survival rate of DKT were not significantly different from SKT, where survival rates were above 85%. Mice with DKT showed less injury and quicker recovery with lower plasma creatinine (Pcr) and higher GFR than SKT mice (Pcr = 0.34 and 0.17 mg/dl in DKT vs. 0.50 and 0.36 mg/dl in SKT at 1 and 3 days, respectively; GFR = 215 and 131 µl/min for DKT and SKT, respectively). In addition, the DKT exhibited better renal functional reserve and long-term outcome of renal graft function than SKT based on the response to acute volume expansion. In conclusion, we have successfully generated a mouse DKT model. The hemodynamic responses of DKT better mimic physiological situations with less kidney injury and better recovery than SKT because of reduced confounding factors such as single nephron hyperfiltration. We anticipate DKT in mice will provide an additional tool for evaluation of renal significance in physiology and disease.

  17. Single K ATP channel opening in response to action potential firing in mouse dentate granule neurons.

    Science.gov (United States)

    Tanner, Geoffrey R; Lutas, Andrew; Martínez-François, Juan Ramón; Yellen, Gary

    2011-06-08

    ATP-sensitive potassium channels (K(ATP) channels) are important sensors of cellular metabolic state that link metabolism and excitability in neuroendocrine cells, but their role in nonglucosensing central neurons is less well understood. To examine a possible role for K(ATP) channels in modulating excitability in hippocampal circuits, we recorded the activity of single K(ATP) channels in cell-attached patches of granule cells in the mouse dentate gyrus during bursts of action potentials generated by antidromic stimulation of the mossy fibers. Ensemble averages of the open probability (p(open)) of single K(ATP) channels over repeated trials of stimulated spike activity showed a transient increase in p(open) in response to action potential firing. Channel currents were identified as K(ATP) channels through blockade with glibenclamide and by comparison with recordings from Kir6.2 knock-out mice. The transient elevation in K(ATP) p(open) may arise from submembrane ATP depletion by the Na(+)-K(+) ATPase, as the pump blocker strophanthidin reduced the magnitude of the elevation. Both the steady-state and stimulus-elevated p(open) of the recorded channels were higher in the presence of the ketone body R-β-hydroxybutyrate, consistent with earlier findings that ketone bodies can affect K(ATP) activity. Using perforated-patch recording, we also found that K(ATP) channels contribute to the slow afterhyperpolarization following an evoked burst of action potentials. We propose that activity-dependent opening of K(ATP) channels may help granule cells act as a seizure gate in the hippocampus and that ketone-body-mediated augmentation of the activity-dependent opening could in part explain the effect of the ketogenic diet in reducing epileptic seizures.

  18. Response of mouse tongue epithelium to single doses of bleomycin and radiation

    International Nuclear Information System (INIS)

    Dorr, W.; Hirler, E.; Honig, M.

    1993-01-01

    Both bleomycin (BLM) and local X-irradiation (25 kV) induce denudation in the tongue epithelium of the C3H-Neuherberg mouse in a dose-dependent manner. In the present study the effect of BLM alone and of combined single doses of drug and radiation were studied using the incidence of epithelial denudation as the end-point. In 'time-line' experiments, 8 mg/kg BLM were given before or after graded doses of X-rays. BLM treatment required a reduction of the radiation dose (ED 50 ) from 15 Gy to 5-7 Gy, independent of sequence or time interval. In contrast, the time course of the response was clearly dependent on the treatment interval. Latency decreased when the drug was injected less than 2 h before irradiation with minimum latency observed at 30 min. Isobologram analysis of experiments with varying combinations of X-rays and BLM demonstrated that small drug doses were relatively more effective than larger doses, suggesting an upward concavity of the BLM dose-effective curve in vivo, i.e. a 'negative shoulder' of the curve in the low dose region. In contrast to the response to X-rays alone, which has a constant latent time to ulcer of 10 days, the latency in combined treatment was clearly shortened with increasing drug dose and at high doses eventually approximated the epithelial turnover time of 5 days. The data suggest that BLM both as a single agent and in combination with X-rays reduced the probability of abortive divisions and through this effect shortened the latent time to epithelial denudation. (author)

  19. The Effect of Single Pyramidal Neuron Firing Within Layer 2/3 and Layer 4 in Mouse V1.

    Science.gov (United States)

    Meyer, Jochen F; Golshani, Peyman; Smirnakis, Stelios M

    2018-01-01

    The influence of cortical cell spiking activity on nearby cells has been studied extensively in vitro . Less is known, however, about the impact of single cell firing on local cortical networks in vivo . In a pioneering study, Kwan and Dan (Kwan and Dan, 2012) reported that in mouse layer 2/3 (L2/3), under anesthesia , stimulating a single pyramidal cell recruits ~2.1% of neighboring units. Here we employ two-photon calcium imaging in layer 2/3 of mouse V1, in conjunction with single-cell patch clamp stimulation in layer 2/3 or layer 4, to probe, in both the awake and lightly anesthetized states , how (i) activating single L2/3 pyramidal neurons recruits neighboring units within L2/3 and from layer 4 (L4) to L2/3, and whether (ii) activating single pyramidal neurons changes population activity in local circuit. To do this, it was essential to develop an algorithm capable of quantifying how sensitive the calcium signal is at detecting effectively recruited units ("followers"). This algorithm allowed us to estimate the chance of detecting a follower as a function of the probability that an epoch of stimulation elicits one extra action potential (AP) in the follower cell. Using this approach, we found only a small fraction (layer-2/3 or layer-4 pyramidal neurons produces few (<1% of local units) reliable single-cell followers in L2/3 of mouse area V1, either under light anesthesia or in quiet wakefulness: instead, single cell stimulation was found to elevate aggregate population activity in a weak but highly distributed fashion.

  20. Single cell analysis of caspase-3 in apoptotic and non-apoptotic cells during mouse limb development

    Czech Academy of Sciences Publication Activity Database

    Adamová, Eva; Klepárník, Karel; Matalová, E.

    2014-01-01

    Roč. 3, - (2014), PP58 ISSN 2052-1219. [European Calcified Tissue Society Congress /41./. 17.05.2014-20.05.2014, Praha] R&D Projects: GA ČR GAP206/11/2377; GA ČR(CZ) GA14-28254S Institutional support: RVO:68081715 Keywords : single cell analysis * caspase-3 * mouse limb development Subject RIV: CB - Analytical Chemistry, Separation

  1. Single cell lineage analysis of mouse embryonic stem cells at the exit from pluripotency

    Directory of Open Access Journals (Sweden)

    Jamie Trott

    2013-08-01

    Understanding how interactions between extracellular signalling pathways and transcription factor networks influence cellular decision making will be crucial for understanding mammalian embryogenesis and for generating specialised cell types in vitro. To this end, pluripotent mouse Embryonic Stem (mES cells have proven to be a useful model system. However, understanding how transcription factors and signalling pathways affect decisions made by individual cells is confounded by the fact that measurements are generally made on groups of cells, whilst individual mES cells differentiate at different rates and towards different lineages, even in conditions that favour a particular lineage. Here we have used single-cell measurements of transcription factor expression and Wnt/β-catenin signalling activity to investigate their effects on lineage commitment decisions made by individual cells. We find that pluripotent mES cells exhibit differing degrees of heterogeneity in their expression of important regulators from pluripotency, depending on the signalling environment to which they are exposed. As mES cells differentiate, downregulation of Nanog and Oct4 primes cells for neural commitment, whilst loss of Sox2 expression primes cells for primitive streak commitment. Furthermore, we find that Wnt signalling acts through Nanog to direct cells towards a primitive streak fate, but that transcriptionally active β-catenin is associated with both neural and primitive streak commitment. These observations confirm and extend previous suggestions that pluripotency genes influence lineage commitment and demonstrate how their dynamic expression affects the direction of lineage commitment, whilst illustrating two ways in which the Wnt signalling pathway acts on this network during cell fate assignment.

  2. Aerodynamic drag on intermodal railcars

    Science.gov (United States)

    Kinghorn, Philip; Maynes, Daniel

    2014-11-01

    The aerodynamic drag associated with transport of commodities by rail is becoming increasingly important as the cost of diesel fuel increases. This study aims to increase the efficiency of intermodal cargo trains by reducing the aerodynamic drag on the load carrying cars. For intermodal railcars a significant amount of aerodynamic drag is a result of the large distance between loads that often occurs and the resulting pressure drag resulting from the separated flow. In the present study aerodynamic drag data have been obtained through wind tunnel testing on 1/29 scale models to understand the savings that may be realized by judicious modification to the size of the intermodal containers. The experiments were performed in the BYU low speed wind tunnel and the test track utilizes two leading locomotives followed by a set of five articulated well cars with double stacked containers. The drag on a representative mid-train car is measured using an isolated load cell balance and the wind tunnel speed is varied from 20 to 100 mph. We characterize the effect that the gap distance between the containers and the container size has on the aerodynamic drag of this representative rail car and investigate methods to reduce the gap distance.

  3. TFH cells accumulate in mucosal tissues of humanized-DRAG mice and are highly permissive to HIV-1

    Science.gov (United States)

    Allam, Atef; Majji, Sai; Peachman, Kristina; Jagodzinski, Linda; Kim, Jiae; Ratto-Kim, Silvia; Wijayalath, Wathsala; Merbah, Melanie; Kim, Jerome H.; Michael, Nelson L.; Alving, Carl R.; Casares, Sofia; Rao, Mangala

    2015-01-01

    CD4+ T follicular helper cells (TFH) in germinal centers are required for maturation of B-cells. While the role of TFH-cells has been studied in blood and lymph nodes of HIV-1 infected individuals, its role in the mucosal tissues has not been investigated. We show that the gut and female reproductive tract (FRT) of humanized DRAG mice have a high level of human lymphocytes and a high frequency of TFH (CXCR5+PD-1++) and precursor-TFH (CXCR5+PD-1+) cells. The majority of TFH-cells expressed CCR5 and CXCR3 and are the most permissive to HIV-1 infection. A single low-dose intravaginal HIV-1 challenge of humanized DRAG mice results in 100% infectivity with accumulation of TFH-cells mainly in the Peyer’s patches and FRT. The novel finding of TFH-cells in the FRT may contribute to the high susceptibility of DRAG mice to HIV-1 infection. This mouse model thus provides new opportunities to study TFH-cells and to evaluate HIV-1 vaccines. PMID:26034905

  4. Quantitative mouse brain phenotyping based on single and multispectral MR protocols

    Science.gov (United States)

    Badea, Alexandra; Gewalt, Sally; Avants, Brian B.; Cook, James J.; Johnson, G. Allan

    2013-01-01

    Sophisticated image analysis methods have been developed for the human brain, but such tools still need to be adapted and optimized for quantitative small animal imaging. We propose a framework for quantitative anatomical phenotyping in mouse models of neurological and psychiatric conditions. The framework encompasses an atlas space, image acquisition protocols, and software tools to register images into this space. We show that a suite of segmentation tools (Avants, Epstein et al., 2008) designed for human neuroimaging can be incorporated into a pipeline for segmenting mouse brain images acquired with multispectral magnetic resonance imaging (MR) protocols. We present a flexible approach for segmenting such hyperimages, optimizing registration, and identifying optimal combinations of image channels for particular structures. Brain imaging with T1, T2* and T2 contrasts yielded accuracy in the range of 83% for hippocampus and caudate putamen (Hc and CPu), but only 54% in white matter tracts, and 44% for the ventricles. The addition of diffusion tensor parameter images improved accuracy for large gray matter structures (by >5%), white matter (10%), and ventricles (15%). The use of Markov random field segmentation further improved overall accuracy in the C57BL/6 strain by 6%; so Dice coefficients for Hc and CPu reached 93%, for white matter 79%, for ventricles 68%, and for substantia nigra 80%. We demonstrate the segmentation pipeline for the widely used C57BL/6 strain, and two test strains (BXD29, APP/TTA). This approach appears promising for characterizing temporal changes in mouse models of human neurological and psychiatric conditions, and may provide anatomical constraints for other preclinical imaging, e.g. fMRI and molecular imaging. This is the first demonstration that multiple MR imaging modalities combined with multivariate segmentation methods lead to significant improvements in anatomical segmentation in the mouse brain. PMID:22836174

  5. Gravitational waves and dragging effects

    Science.gov (United States)

    Bičák, Jiří; Katz, Joseph; Lynden-Bell, Donald

    2008-08-01

    Linear and rotational dragging effects of gravitational waves on local inertial frames are studied in purely vacuum spacetimes. First, the linear dragging caused by a simple cylindrical pulse is investigated. Surprisingly strong transverse effects of the pulse are exhibited. The angular momentum in cylindrically symmetric spacetimes is then defined and confronted with some results in the literature. In the main part, a general procedure is developed for studying weak gravitational waves with translational but not axial symmetry which can carry angular momentum. After a suitable averaging the rotation of local inertial frames due to such rotating waves can be calculated explicitly and illustrated graphically. This is done in detail in the accompanying paper. Finally, the rotational dragging is given for strong cylindrical waves interacting with a rotating cosmic string with a small angular momentum.

  6. Progress report on INEL full flow drag screen

    International Nuclear Information System (INIS)

    Arave, A.E.; Colson, J.B.; Fincke, J.R.

    1977-01-01

    The objective in developing a full flow drag screen is to obtain a total momentum flux measurement which when combined with a suitable independent velocity or density measurement will yield a total mass flux. The major design considerations are predicated by the fact that an accurate momentum flux measurement must be made over a wide range of flow conditions. The device should exhibit a constant calibration regardless of Reynolds number, void fraction, slip ratio, or flow regime. The dynamics of drag devices are well understood in single-phase flows. This is not true for two-phase flows. The present development program is directed toward gaining an understanding of the dynamics of drag devices which sample the total area of a pipe in two-phase flow and developing a method for deducing mass flow rate using such a device. Various geometric arrangements are to be investigated. Testing to date has shown excellent results using a round wire mesh screen in the Semiscale air/water loop. Future air/water testing will include perforated plates and wire meshes with both rectangular and diamond shaped cross sections. Analytical models of the hydrodynamics of the drag screen as well as the associated density or velocity measuring device are being used to select the optimum configuration. Alternate force sensing methods are also being considered. These include single and multiple transducer arrangements. Multistage springs and pressure drop across the body are to be evaluated for extending the dynamic range of the drag body

  7. Ultrastructural comparison of single dose hydroxyurea and ionizing radiation on mouse hair roots

    Energy Technology Data Exchange (ETDEWEB)

    Pearson, R.W.; Malkinson, F.D.

    1986-01-01

    Growing mouse vibrissae were investigated by light and electron microscopy to compare the effects of hydroxyurea (1500 mgkg/sup -1/ intraperitoneally) and gamma radiation (10 Gy). In the case of the drug, specimens were obtained from 30 min to 9 days post-treatment. Irradiated specimens were taken at intervals up to 1.5 years post-irradiation. The morphological alterations were similar for both types of insult, but the time sequences of events were quite different. The post-irradiation recovery period was vastly extended compared with that of the hydroxyurea treated hair roots.

  8. Ultrastructural comparison of single dose hydroxyurea and ionizing radiation on mouse hair roots

    International Nuclear Information System (INIS)

    Pearson, R.W.; Malkinson, F.D.

    1986-01-01

    Growing mouse vibrissae were investigated by light and electron microscopy to compare the effects of hydroxyurea (1500 mgkg -1 intraperitoneally) and gamma radiation (10 Gy). In the case of the drug, specimens were obtained from 30 min to 9 days post-treatment. Irradiated specimens were taken at intervals up to 1.5 years post-irradiation. The morphological alterations were similar for both types of insult, but the time sequences of events were quite different. The post-irradiation recovery period was vastly extended compared with that of the hydroxyurea treated hair roots. (UK)

  9. Design and development of drag-disc flowmeter for measurement of transient two-phase flow

    International Nuclear Information System (INIS)

    Sreenivas Rao, G.; Kukreja, V.; Dolas, P.K.; Venkat Raj, V.

    1990-01-01

    Experiments have been carried out to test the suitability of drag-disc flowmeter for measuring two-phase flow. Calibration tests carried out under single-phase and two-phase flow conditions have confirmed the suitability of the drag-disc flowmeter. The experimental work and the results obtained are presented and discussed in the paper. (author). 3 refs., 6 figs

  10. Drag Reduction by Leidenfrost Vapor Layers

    KAUST Repository

    Vakarelski, Ivan Uriev; Marston, Jeremy O.; Chan, Derek Y. C.; Thoroddsen, Sigurdur T

    2011-01-01

    , we show that such vapor layers can reduce the hydrodynamic drag by over 85%. These results appear to approach the ultimate limit of drag reduction possible by different methods based on gas-layer lubrication and can stimulate the development

  11. Absence of linkage of apparently single gene mediated ADHD with the human syntenic region of the mouse mutant coloboma

    Energy Technology Data Exchange (ETDEWEB)

    Hess, E.J.; Rogan, P.K.; Domoto, M. [Pennsylvania State Univ. College of Medicine, Hershey, PA (United States)] [and others

    1995-12-18

    Attention deficit disorder (ADHD) is a complex biobehavioral phenotype which affects up to 8% of the general population and often impairs social, academic, and job performance. Its origins are heterogeneous, but a significant genetic component is suggested by family and twin studies. The murine strain, coloboma, displays a spontaneously hyperactive phenotype that is responsive to dextroamphetamine and has been proposed as a genetic model for ADHD. Coloboma is a semi-dominant mutation that is caused by a hemizygous deletion of the SNAP-25 and other genes on mouse chromosome 2q. To test the possibility that the human homolog of the mouse coloboma gene(s) could be responsible for ADHD, we have carried out linkage studies with polymorphic markers in the region syntenic to coloboma (20p11-p12). Five families in which the pattern of inheritance of ADHD appears to be autosomal dominant were studied. Segregation analysis of the traits studied suggested that the best fitting model was a sex-influenced, single gene, Mendelian pattern. Several genetic models were evaluated based on estimates of penetrance, phenocopy rate, and allele frequency derived from our patient population and those of other investigators. No significant linkage was detected between the disease locus and markers spanning this chromosome 20 interval. 39 refs., 2 figs., 1 tab.

  12. Enzymatic amplification of a Y chromosome repeat in a single blastomere allows identification of the sex of preimplantation mouse embryos

    International Nuclear Information System (INIS)

    Bradbury, M.W.; Isola, L.M.; Gordon, J.W.

    1990-01-01

    The polymerase chain reaction (PCR) technique has been adapted to identify the sex of preimplantation mouse embryos rapidly. PCR was used to amplify a specific repeated DNA sequence on the Y chromosome from a single isolated blastomere in under 12 hr. The remainder of the biopsied embryo was then transferred to a pseudopregnant female and carried to term. Using this technique, 72% of embryos can be classed as potentially either male or female. Transfers of such embryos have produced pregnancies with 8/8 fetuses (100%) being of the predicted sex. Variations of the technique have demonstrated certain limitations to the present procedure as well as indicated possible strategies for improvement of the assay. The PCR technique may have wide application in the genetic analysis of preimplantation embryos

  13. Severe, multimodal stress exposure induces PTSD-like characteristics in a mouse model of single prolonged stress.

    Science.gov (United States)

    Perrine, Shane A; Eagle, Andrew L; George, Sophie A; Mulo, Kostika; Kohler, Robert J; Gerard, Justin; Harutyunyan, Arman; Hool, Steven M; Susick, Laura L; Schneider, Brandy L; Ghoddoussi, Farhad; Galloway, Matthew P; Liberzon, Israel; Conti, Alana C

    2016-04-15

    Appropriate animal models of posttraumatic stress disorder (PTSD) are needed because human studies remain limited in their ability to probe the underlying neurobiology of PTSD. Although the single prolonged stress (SPS) model is an established rat model of PTSD, the development of a similarly-validated mouse model emphasizes the benefits and cross-species utility of rodent PTSD models and offers unique methodological advantages to that of the rat. Therefore, the aims of this study were to develop and describe a SPS model for mice and to provide data that support current mechanisms relevant to PTSD. The mouse single prolonged stress (mSPS) paradigm, involves exposing C57Bl/6 mice to a series of severe, multimodal stressors, including 2h restraint, 10 min group forced swim, exposure to soiled rat bedding scent, and exposure to ether until unconsciousness. Following a 7-day undisturbed period, mice were tested for cue-induced fear behavior, effects of paroxetine on cue-induced fear behavior, extinction retention of a previously extinguished fear memory, dexamethasone suppression of corticosterone (CORT) response, dorsal hippocampal glucocorticoid receptor protein and mRNA expression, and prefrontal cortex glutamate levels. Exposure to mSPS enhanced cue-induced fear, which was attenuated by oral paroxetine treatment. mSPS also disrupted extinction retention, enhanced suppression of stress-induced CORT response, increased mRNA expression of dorsal hippocampal glucocorticoid receptors and decreased prefrontal cortex glutamate levels. These data suggest that the mSPS model is a translationally-relevant model for future PTSD research with strong face, construct, and predictive validity. In summary, mSPS models characteristics relevant to PTSD and this severe, multimodal stress modifies fear learning in mice that coincides with changes in the hypothalamo-pituitary-adrenal (HPA) axis, brain glucocorticoid systems, and glutamatergic signaling in the prefrontal cortex

  14. Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesis.

    Science.gov (United States)

    Dong, Ji; Hu, Yuqiong; Fan, Xiaoying; Wu, Xinglong; Mao, Yunuo; Hu, Boqiang; Guo, Hongshan; Wen, Lu; Tang, Fuchou

    2018-03-14

    Organogenesis is crucial for proper organ formation during mammalian embryonic development. However, the similarities and shared features between different organs and the cellular heterogeneity during this process at single-cell resolution remain elusive. We perform single-cell RNA sequencing analysis of 1916 individual cells from eight organs and tissues of E9.5 to E11.5 mouse embryos, namely, the forebrain, hindbrain, skin, heart, somite, lung, liver, and intestine. Based on the regulatory activities rather than the expression patterns, all cells analyzed can be well classified into four major groups with epithelial, mesodermal, hematopoietic, and neuronal identities. For different organs within the same group, the similarities and differences of their features and developmental paths are revealed and reconstructed. We identify mutual interactions between epithelial and mesenchymal cells and detect epithelial cells with prevalent mesenchymal features during organogenesis, which are similar to the features of intermediate epithelial/mesenchymal cells during tumorigenesis. The comprehensive transcriptome at single-cell resolution profiled in our study paves the way for future mechanistic studies of the gene-regulatory networks governing mammalian organogenesis.

  15. Further development of drag bodies for the measurement of mass flow rates during blowdown experiments

    International Nuclear Information System (INIS)

    Brockmann, E.; John, H.; Reimann, J.

    1983-01-01

    Drag bodies have already been used for sometime for the measurement of mass flow rates in blowdown experiments. Former research concerning the drag body behaviour in non-homogeneous two-phase flows frequently dealt with special effects by means of theoretical models only. For pipe flows most investigations were conducted for ratios of drag plate area to pipe cross section smaller 0.02. The present paper gives the results of experiments with drag bodies in a horizontal, non-homogeneous two-phase pipe flow with slip, which were carried through under the sponsorship of the German Ministry for Research and Technology (BMFT). Special interest was layed on the behaviour of the drag coefficient in stationary flows and at various cross sectional ratios. Both design and response of various drag bodies, which were developed at the Battelle-Institut, were tested in stationary and instationary two-phase flows. The influences of density and velocity profiles as well as the drag body position were studied. The results demonstrate, that the drag body is capable of measuring mass flow rates in connection with a gamma densitometer also in non-homogeneous two-phase flows. Satisfying results could be obtained, using simply the drag coefficient which was determined from single-phase flow calibrations

  16. A single amino acid mutation in SNAP-25 induces anxiety-related behavior in mouse.

    Directory of Open Access Journals (Sweden)

    Masakazu Kataoka

    Full Text Available Synaptosomal-associated protein of 25 kDa (SNAP-25 is a presynaptic protein essential for neurotransmitter release. Previously, we demonstrate that protein kinase C (PKC phosphorylates Ser(187 of SNAP-25, and enhances neurotransmitter release by recruiting secretory vesicles near to the plasma membrane. As PKC is abundant in the brain and SNAP-25 is essential for synaptic transmission, SNAP-25 phosphorylation is likely to play a crucial role in the central nervous system. We therefore generated a mutant mouse, substituting Ser(187 of SNAP-25 with Ala using "knock-in" technology. The most striking effect of the mutation was observed in their behavior. The homozygous mutant mice froze readily in response to environmental change, and showed strong anxiety-related behavior in general activity and light and dark preference tests. In addition, the mutant mice sometimes exhibited spontaneously occurring convulsive seizures. Microdialysis measurements revealed that serotonin and dopamine release were markedly reduced in amygdala. These results clearly indicate that PKC-dependent SNAP-25 phosphorylation plays a critical role in the regulation of emotional behavior as well as the suppression of epileptic seizures, and the lack of enhancement of monoamine release is one of the possible mechanisms underlying these defects.

  17. A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation.

    Science.gov (United States)

    Nestorowa, Sonia; Hamey, Fiona K; Pijuan Sala, Blanca; Diamanti, Evangelia; Shepherd, Mairi; Laurenti, Elisa; Wilson, Nicola K; Kent, David G; Göttgens, Berthold

    2016-08-25

    Maintenance of the blood system requires balanced cell fate decisions by hematopoietic stem and progenitor cells (HSPCs). Because cell fate choices are executed at the individual cell level, new single-cell profiling technologies offer exciting possibilities for mapping the dynamic molecular changes underlying HSPC differentiation. Here, we have used single-cell RNA sequencing to profile more than 1600 single HSPCs, and deep sequencing has enabled detection of an average of 6558 protein-coding genes per cell. Index sorting, in combination with broad sorting gates, allowed us to retrospectively assign cells to 12 commonly sorted HSPC phenotypes while also capturing intermediate cells typically excluded by conventional gating. We further show that independently generated single-cell data sets can be projected onto the single-cell resolution expression map to directly compare data from multiple groups and to build and refine new hypotheses. Reconstruction of differentiation trajectories reveals dynamic expression changes associated with early lymphoid, erythroid, and granulocyte-macrophage differentiation. The latter two trajectories were characterized by common upregulation of cell cycle and oxidative phosphorylation transcriptional programs. By using external spike-in controls, we estimate absolute messenger RNA (mRNA) levels per cell, showing for the first time that despite a general reduction in total mRNA, a subset of genes shows higher expression levels in immature stem cells consistent with active maintenance of the stem-cell state. Finally, we report the development of an intuitive Web interface as a new community resource to permit visualization of gene expression in HSPCs at single-cell resolution for any gene of choice. © 2016 by The American Society of Hematology.

  18. Coulomb drag in the mesoscopic regime

    DEFF Research Database (Denmark)

    Mortensen, N.A.; Flensberg, Karsten; Jauho, Antti-Pekka

    2002-01-01

    We present a theory for Coulomb drag between two mesoscopic systems which expresses the drag in terms of scattering matrices and wave functions. The formalism can be applied to both ballistic and disordered systems and the consequences can be studied either by numerical simulations or analytic...... means such as perturbation theory or random matrix theory. The physics of Coulomb drag in the mesoscopic regime is very different from Coulomb drag between extended electron systems. In the mesoscopic regime we in general find fluctuations of the drag comparable to the mean value. Examples are vanishing...

  19. Coulomb drag in coherent mesoscopic systems

    DEFF Research Database (Denmark)

    Mortensen, Asger; Flensberg, Karsten; Jauho, Antti-Pekka

    2001-01-01

    We present a theory for Coulomb drag between two mesoscopic systems. Our formalism expresses the drag in terms of scattering matrices and wave functions, and its range of validity covers both ballistic and disordered systems. The consequences can be worked out either by analytic means, such as th......We present a theory for Coulomb drag between two mesoscopic systems. Our formalism expresses the drag in terms of scattering matrices and wave functions, and its range of validity covers both ballistic and disordered systems. The consequences can be worked out either by analytic means......, such as the random matrix theory, or by numerical simulations. We show that Coulomb drag is sensitive to localized states. which usual transport measurements do not probe. For chaotic 2D systems we find a vanishing average drag, with a nonzero variance. Disordered 1D wires show a finite drag, with a large variance...

  20. Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells.

    Science.gov (United States)

    Banáth, J P; Bañuelos, C A; Klokov, D; MacPhail, S M; Lansdorp, P M; Olive, P L

    2009-05-01

    Pluripotent mouse embryonic stem cells (mES cells) exhibit approximately 100 large gammaH2AX repair foci in the absence of measurable numbers of DNA double-strand breaks. Many of these cells also show excessive numbers of DNA single-strand breaks (>10,000 per cell) when analyzed using the alkaline comet assay. To understand the reasons for these unexpected observations, various methods for detecting DNA strand breaks were applied to wild-type mES cells and to mES cells lacking H2AX, ATM, or DNA-PKcs. H2AX phosphorylation and expression of other repair complexes were measured using flow and image analysis of antibody-stained cells. Results indicate that high numbers of endogenous gammaH2AX foci and single-strand breaks in pluripotent mES cells do not require ATM or DNA-PK kinase activity and appear to be associated with global chromatin decondensation rather than pre-existing DNA damage. This will limit applications of gammaH2AX foci analysis in mES cells to relatively high levels of initial or residual DNA damage. Excessive numbers of single-strand breaks in the alkaline comet assay can be explained by the vulnerability of replicating chromatin in mES cells to osmotic shock. This suggests that caution is needed in interpreting results with the alkaline comet assay when applied to certain cell types or after treatment with agents that make chromatin vulnerable to osmotic changes. Differentiation of mES cells caused a reduction in histone acetylation, gammaH2AX foci intensity, and DNA single-strand breakage, providing a link between chromatin structural organization, excessive gammaH2AX foci, and sensitivity of replicating mES cell chromatin to osmotic shock.

  1. Chasing the precursor of functional hematopoietic stem cells at the single cell levels in mouse embryos.

    Science.gov (United States)

    Wang, Xiaochen; Gong, Yuemin; Ema, Hideo

    2016-07-22

    Adult hematopoietic stem cells (HSCs), the ideal system for regenerative research, were isolated at single cell levels decades ago, whereas studies on embryonic HSCs are much more difficult. Zhou et al identified a new pre-HSC cell surface marker, CD201, by which they isolated pre-HSCs at single cell levels for further analyses. The novel expression pattern of HSC development is revealed, including the fundamental role of mammalian targets of rapamycin (mTOR) signaling pathway in HSCs emergence, and the repopulation potential of S/G2/M phase pre-HSCs. Deeper understandings of the cellular origin and developmental regulatory network of HSCs are essential to develop new strategies of generating HSCs in vitro for clinical application.

  2. Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells.

    Directory of Open Access Journals (Sweden)

    John J Vincent

    Full Text Available The cell intrinsic programming that regulates mammalian primordial germ cell (PGC development in the pre-gonadal stage is challenging to investigate. To overcome this we created a transgene-free method for generating PGCs in vitro (iPGCs from mouse embryonic stem cells (ESCs. Using labeling for SSEA1 and cKit, two cell surface molecules used previously to isolate presumptive iPGCs, we show that not all SSEA1+/cKit+ double positive cells exhibit a PGC identity. Instead, we determined that selecting for cKit(bright cells within the SSEA1+ fraction significantly enriches for the putative iPGC population. Single cell analysis comparing SSEA1+/cKit(bright iPGCs to ESCs and embryonic PGCs demonstrates that 97% of single iPGCs co-express PGC signature genes Blimp1, Stella, Dnd1, Prdm14 and Dazl at similar levels to e9.5-10.5 PGCs, whereas 90% of single mouse ESC do not co-express PGC signature genes. For the 10% of ESCs that co-express PGC signature genes, the levels are significantly lower than iPGCs. Microarray analysis shows that iPGCs are transcriptionally distinct from ESCs and repress gene ontology groups associated with mesoderm and heart development. At the level of chromatin, iPGCs contain 5-methyl cytosine bases in their DNA at imprinted and non-imprinted loci, and are enriched in histone H3 lysine 27 trimethylation, yet do not have detectable levels of Mvh protein, consistent with a Blimp1-positive pre-gonadal PGC identity. In order to determine whether iPGC formation is dependent upon Blimp1, we generated Blimp1 null ESCs and found that loss of Blimp1 significantly depletes SSEA1/cKit(bright iPGCs. Taken together, the generation of Blimp1-positive iPGCs from ESCs constitutes a robust model for examining cell-intrinsic regulation of PGCs during the Blimp1-positive stage of development.

  3. Assessments of Bubble Dynamics Model and Influential Parameters in Microbubble Drag Reduction

    National Research Council Canada - National Science Library

    Skudarnov, P. V; Lin, C. X

    2006-01-01

    .... The effects of mixture density variation, free stream turbulence intensity, free stream velocity, and surface roughness on the microbubble drag reduction were studied using a single phase model based...

  4. Secretion of an immunoreactive single-chain variable fragment antibody against mouse interleukin 6 by Lactococcus lactis.

    Science.gov (United States)

    Shigemori, Suguru; Ihara, Masaki; Sato, Takashi; Yamamoto, Yoshinari; Nigar, Shireen; Ogita, Tasuku; Shimosato, Takeshi

    2017-01-01

    Interleukin 6 (IL-6) is an important pathogenic factor in development of various inflammatory and autoimmune diseases and cancer. Blocking antibodies against molecules associated with IL-6/IL-6 receptor signaling are an attractive candidate for the prevention or therapy of these diseases. In this study, we developed a genetically modified strain of Lactococcus lactis secreting a single-chain variable fragment antibody against mouse IL-6 (IL6scFv). An IL6scFv-secretion vector was constructed by cloning an IL6scFv gene fragment into a lactococcal secretion plasmid and was electroporated into L. lactis NZ9000 (NZ-IL6scFv). Secretion of recombinant IL6scFv (rIL6scFv) by nisin-induced NZ-IL6scFv was confirmed by western blotting and was optimized by tuning culture conditions. We found that rIL6scFv could bind to commercial recombinant mouse IL-6. This result clearly demonstrated the immunoreactivity of rIL6scFv. This is the first study to engineer a genetically modified strain of lactic acid bacteria (gmLAB) that produces a functional anti-cytokine scFv. Numerous previous studies suggested that mucosal delivery of biomedical proteins using gmLAB is an effective and low-cost way to treat various disorders. Therefore, NZ-IL6scFv may be an attractive tool for the research and development of new IL-6 targeting agents for various inflammatory and autoimmune diseases as well as for cancer.

  5. Mouse single oral dose toxicity test of bupleuri radix aqueous extracts.

    Science.gov (United States)

    Kim, Kyung-Hu; Gam, Cheol-Ou; Choi, Seong-Hun; Ku, Sae-Kwang

    2012-03-01

    The aim of this study was to evaluate the single oral dose toxicity of Bupleuri Radix (BR) aqueous extracts, it has been traditionally used as anti-inflammatory agent, in male and female mice. BR extracts (yield = 16.52%) was administered to female and male ICR mice as an oral dose of 2,000, 1,000 and 500 mg/kg (body weight) according to the recommendation of Korea Food and Drug Administration (KFDA) Guidelines. Animals were monitored for the mortality and changes in body weight, clinical signs and gross observation during 14 days after dosing, upon necropsy; organ weight and histopathology of 14 principal organs were examined. As the results, no BR extracts treatment related mortalities, clinical signs, changes on the body and organ weights, gross and histopathological observations against 14 principal organs were detected up to 2,000 mg/kg in both female and male mice, except for soft feces and related body weight decrease detected in male mice treated with 2,000 mg/kg. Therefore, LD50 (50% lethal dose) and approximate LD of BR aqueous extracts after single oral treatment in female and male mice were considered over 2000 mg/kg, respectively. Although it was also observed that the possibilities of digestive disorders, like soft feces when administered over 2,000 mg/kg of BR extracts in the present study, these possibilities of digestive disorders can be disregard in clinical use because they are transient in the highest dosages male only.

  6. Drag and drop display & builder

    Energy Technology Data Exchange (ETDEWEB)

    Bolshakov, Timofei B.; Petrov, Andrey D.; /Fermilab

    2007-12-01

    The Drag and Drop (DnD) Display & Builder is a component-oriented system that allows users to create visual representations of data received from data acquisition systems. It is an upgrade of a Synoptic Display mechanism used at Fermilab since 2002. Components can be graphically arranged and logically interconnected in the web-startable Project Builder. Projects can be either lightweight AJAX- and SVG-based web pages, or they can be started as Java applications. The new version was initiated as a response to discussions between the LHC Controls Group and Fermilab.

  7. Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia.

    Science.gov (United States)

    Sun, Heng; Miao, Zhengqiang; Zhang, Xin; Chan, Un In; Su, Sek Man; Guo, Sen; Wong, Chris Koon Ho; Xu, Xiaoling; Deng, Chu-Xia

    2018-04-17

    The mammary gland is very intricately and well organized into distinct tissues, including epithelia, endothelia, adipocytes, and stromal and immune cells. Many mammary gland diseases, such as breast cancer arise from abnormalities in the mammary epithelium, which is mainly composed of two distinct lineages, the basal and luminal cells. Because of the limitation of traditional transcriptome analysis of bulk mammary cells, the hierarchy and heterogeneity of mammary cells within these two lineages remain unclear. To this end, using single-cell RNA-Seq coupled with FACS analysis and principal component analysis, we determined gene expression profiles of mammary epithelial cells of virgin and pregnant mice. These analyses revealed a much higher heterogeneity among the mammary cells than has been previously reported and enabled cell classification into distinct subgroups according to signature gene markers present in each group. We also identified and verified a rare CDH5+ cell subpopulation within a basal cell lineage as quiescent mammary stem cells (MaSCs). Moreover, using pseudo-temporal analysis, we reconstructed the developmental trajectory of mammary epithelia and uncovered distinct changes in gene expression and in biological functions of mammary cells along the developmental process. In conclusion, our work greatly refines the resolution of the cellular hierarchy in developing mammary tissues. The discovery of CDH5+ cells as MaSCs in these tissues may have implications for our understanding of the initiation, development, and pathogenesis of mammary tumors. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

  8. Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease.

    Science.gov (United States)

    Hook, Paul W; McClymont, Sarah A; Cannon, Gabrielle H; Law, William D; Morton, A Jennifer; Goff, Loyal A; McCallion, Andrew S

    2018-03-01

    Genetic variation modulating risk of sporadic Parkinson disease (PD) has been primarily explored through genome-wide association studies (GWASs). However, like many other common genetic diseases, the impacted genes remain largely unknown. Here, we used single-cell RNA-seq to characterize dopaminergic (DA) neuron populations in the mouse brain at embryonic and early postnatal time points. These data facilitated unbiased identification of DA neuron subpopulations through their unique transcriptional profiles, including a postnatal neuroblast population and substantia nigra (SN) DA neurons. We use these population-specific data to develop a scoring system to prioritize candidate genes in all 49 GWAS intervals implicated in PD risk, including genes with known PD associations and many with extensive supporting literature. As proof of principle, we confirm that the nigrostriatal pathway is compromised in Cplx1-null mice. Ultimately, this systematic approach establishes biologically pertinent candidates and testable hypotheses for sporadic PD, informing a new era of PD genetic research. Copyright © 2018 American Society of Human Genetics. All rights reserved.

  9. Repopulation dynamics of single haematopoietic stem cells in mouse transplantation experiments: Importance of stem cell composition in competitor cells.

    Science.gov (United States)

    Ema, Hideo; Uchinomiya, Kouki; Morita, Yohei; Suda, Toshio; Iwasa, Yoh

    2016-04-07

    The transplantation of blood tissues from bone marrow into a lethally irradiated animal is an experimental procedure that is used to study how the blood system is reconstituted by haematopoietic stem cells (HSC). In a competitive repopulation experiment, a lethally irradiated mouse was transplanted with a single HSC as a test cell together with a number of bone marrow cells as competitor cells, and the fraction of the test cell progeny (percentage of chimerism) was traced over time. In this paper, we studied the stem cell kinetics in this experimental procedure. The balance between symmetric self-renewal and differentiation divisions in HSC determined the number of cells which HSC produce and the length of time for which HSC live after transplantation. The percentage of chimerism depended on the type of test cell (long-, intermediate-, or short-term HSC), as well as the type and number of HSC included in competitor cells. We next examined two alternative HSC differentiation models, one-step and multi-step differentiation models. Although these models differed in blood cell production, the percentage of chimerism appeared very similar. We also estimated the numbers of different types of HSC in competitor cells. Based on these results, we concluded that the experimental results inevitably include stochasticity with regard to the number and the type of HSC in competitor cells, and that, in order to detect different types of HSC, an appropriate number of competitor cells needs to be used in transplantation experiments. Copyright © 2016. Published by Elsevier Ltd.

  10. Coulomb drag in the mesoscopic regime

    DEFF Research Database (Denmark)

    Mortensen, N. Asger; Flensberg, Karsten; Jauho, Antti-Pekka

    2002-01-01

    We present a theory for Coulomb drug between two mesoscopic systems which expresses the drag in terms of scattering matrices and wave functions. The formalism can be applied to both ballistic and disordered systems and the consequences can be studied either by numerical simulations or analytic...... means such as perturbation theory or random matrix theory. The physics of Coulomb drag in the mesoscopic regime is very different from Coulomb drag between extended electron systems. In the mesoscopic regime we in general find fluctuations of the drag comparable to the mean value. Examples are vanishing...

  11. DOE Project on Heavy Vehicle Aerodynamic Drag

    Energy Technology Data Exchange (ETDEWEB)

    McCallen, R; Salari, K; Ortega, J; Castellucci, P; Pointer, D; Browand, F; Ross, J; Storms, B

    2007-01-04

    Class 8 tractor-trailers consume 11-12% of the total US petroleum use. At highway speeds, 65% of the energy expenditure for a Class 8 truck is in overcoming aerodynamic drag. The project objective is to improve fuel economy of Class 8 tractor-trailers by providing guidance on methods of reducing drag by at least 25%. A 25% reduction in drag would present a 12% improvement in fuel economy at highway speeds, equivalent to about 130 midsize tanker ships per year. Specific goals include: (1) Provide guidance to industry in the reduction of aerodynamic drag of heavy truck vehicles; (2) Develop innovative drag reducing concepts that are operationally and economically sound; and (3) Establish a database of experimental, computational, and conceptual design information, and demonstrate the potential of new drag-reduction devices. The studies described herein provide a demonstration of the applicability of the experience developed in the analysis of the standard configuration of the Generic Conventional Model. The modeling practices and procedures developed in prior efforts have been applied directly to the assessment of new configurations including a variety of geometric modifications and add-on devices. Application to the low-drag 'GTS' configuration of the GCM has confirmed that the error in predicted drag coefficients increases as the relative contribution of the base drag resulting from the vehicle wake to the total drag increases and it is recommended that more advanced turbulence modeling strategies be applied under those circumstances. Application to a commercially-developed boat tail device has confirmed that this restriction does not apply to geometries where the relative contribution of the base drag to the total drag is reduced by modifying the geometry in that region. Application to a modified GCM geometry with an open grille and radiator has confirmed that the underbody flow, while important for underhood cooling, has little impact on the drag

  12. Improvements of evaporation drag model

    International Nuclear Information System (INIS)

    Li Xiaoyan; Yang Yanhua; Xu Jijun

    2004-01-01

    A special observable experiment facility has been established, and a series of experiments have been carried out on this facility by pouring one or several high-temperature particles into a water pool. The experiment has verified the evaporation drag model, which believe the non-symmetric profile of the local evaporation rate and the local density of the vapor would bring about a resultant force on the hot particle so as to resist its motion. However, in Yang's evaporation drag model, radiation heat transfer is taken as the only way to transfer heat from hot particle to the vapor-liquid interface and all of the radiation energy is deposited on the vapor-liquid interface, thus contributing to the vaporization rate and mass balance of the vapor film. So, the heat conduction and the heat convection are taken into account in improved model. At the same time, the improved model given by this paper presented calculations of the effect of hot particles temperature on the radiation absorption behavior of water

  13. Drag reduction statistics in a channel flow

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez-Bernal, Jose A. [Instituto Politecnico Nacional, LABINTHAP-SEPI-ESIME, Edif. 5, 3er piso Col. Lindavista, Mexico DF 07738 (Mexico); Hassan, Yassin A.; Gutierrez-Torres, Claudia del C. [Nuclear Engineering Department, Texas A and M University, College Station, TX 77843-3123 (United States)

    2005-07-01

    Full text of publication follows: Methods to reduce the drag have been studied for many years because of the promising payoffs that can be attained. In this investigation, the evaluation of statistics such as skewness, flatness, spectra of the stream-wise velocity fluctuations is performed for single phase flow and for two phase flow. Micro-bubbles with an average diameter of 30 {mu}m and a local void fraction of 4.8 % were produced by electrolysis and injected inside the boundary layer. This value of void fraction produced a 38.45 % decrease of the drag. The experiments were conducted in a channel flow at a Reynolds number Re 5128 (considering half height of the channel, the bulk velocity and the kinematics viscosity of the water). The channel was made of acrylic due to the optical properties of this material; its dimensions are 3.85 m long, 0.206 m wide and 0.056 m high. A pressure transducer that ranges from 0 to 35 Pa is located in the test station to measure the pressure drop in single phase flow; this pressure value is used to calculate the shear wall stress. The shear wall stress of two phase flow was measured from the velocity fields obtained from Particle Image Velocimetry (PIV) technique. PIV was utilized to measure instantaneous velocity fields in the stream-wise-normal (x-y) plane. The use of low-local values of void fraction caused a reduction of undesirable speckles effects and an absence of extreme brightness provoked by high bubble saturation. The measurements were carried out in the upper wall of the channel at 3.15 m downstream the inlet's channel. The PIV system is formed by a CCD camera with a resolution of 1008 x 1018 pixels and a double pulse laser with a maximum power 400 mJ and a wavelength of 532 nm (green light). The laser beam was transformed into a sheet of light by an array of cylindrical lenses. Two hundred frames with an area of 1.28 cm{sup 2} were recorded to obtain one hundred velocity fields. The time separation between

  14. Drag reduction statistics in a channel flow

    International Nuclear Information System (INIS)

    Jimenez-Bernal, Jose A.; Hassan, Yassin A.; Gutierrez-Torres, Claudia del C.

    2005-01-01

    Full text of publication follows: Methods to reduce the drag have been studied for many years because of the promising payoffs that can be attained. In this investigation, the evaluation of statistics such as skewness, flatness, spectra of the stream-wise velocity fluctuations is performed for single phase flow and for two phase flow. Micro-bubbles with an average diameter of 30 μm and a local void fraction of 4.8 % were produced by electrolysis and injected inside the boundary layer. This value of void fraction produced a 38.45 % decrease of the drag. The experiments were conducted in a channel flow at a Reynolds number Re 5128 (considering half height of the channel, the bulk velocity and the kinematics viscosity of the water). The channel was made of acrylic due to the optical properties of this material; its dimensions are 3.85 m long, 0.206 m wide and 0.056 m high. A pressure transducer that ranges from 0 to 35 Pa is located in the test station to measure the pressure drop in single phase flow; this pressure value is used to calculate the shear wall stress. The shear wall stress of two phase flow was measured from the velocity fields obtained from Particle Image Velocimetry (PIV) technique. PIV was utilized to measure instantaneous velocity fields in the stream-wise-normal (x-y) plane. The use of low-local values of void fraction caused a reduction of undesirable speckles effects and an absence of extreme brightness provoked by high bubble saturation. The measurements were carried out in the upper wall of the channel at 3.15 m downstream the inlet's channel. The PIV system is formed by a CCD camera with a resolution of 1008 x 1018 pixels and a double pulse laser with a maximum power 400 mJ and a wavelength of 532 nm (green light). The laser beam was transformed into a sheet of light by an array of cylindrical lenses. Two hundred frames with an area of 1.28 cm 2 were recorded to obtain one hundred velocity fields. The time separation between consecutive pulses

  15. Design and development of drag-disc flow meter for measurement of transient two-phase flow

    International Nuclear Information System (INIS)

    Sreenivas Rao, G.; Kukreja, V.; Dolas, P.K.; Venkat Raj, V.

    1989-01-01

    Experiments have been carried out to test the suitability of drag-disc flowmeter for measuring two-phase flow. Calibration tests carried out under single-phase and two-phase flow conditions have confirmed the suitability of the drag-disc flowmeter. The experimental work and the results obtained are presented and discussed in the paper. (author). 6 figs

  16. Reducing drag of a commuter train, using engine exhaust momentum

    Science.gov (United States)

    Ha, Dong Keun

    The objective of this thesis was to perform numerical investigations of two different methods of injecting fluid momentum into the air flow above a commuter train to reduce its drag. Based on previous aerodynamic modifications of heavy duty trucks in improving fuel efficiency, two structural modifications were designed and applied to a Metrolink Services commuter train in the Los Angeles (LA) County area to reduce its drag and subsequently improve fuel efficiency. The first modification was an L-shaped channel, added to the exhaust cooling fan above the locomotive roof to divert and align the exhaust gases in the axial direction. The second modification was adding an airfoil shaped lid over the L-shape channel, to minimize the drag of the perturbed structure, and thus reduce the overall drag. The computational fluid dynamic (CFD) software CCM+ from CD-Adapco with the ?-? turbulence model was used for the simulations. A single train set which consists of three vehicles: one locomotive, one trailer car and one cab car were used. All the vehicles were modeled based on the standard Metrolink fleet train size. The wind speed was at 90 miles per hour (mph), which is the maximum speed for the Orange County Metrolink line. Air was used as the exhaust gas in the simulation. The temperature of the exhausting air emitting out of the cooling fan on the roof was 150 F and the average fan speed was 120 mph. Results showed that with the addition of the lid, momentum injection results in reduced flow separation and pressure recovery behind the locomotive, which reduces the overall drag by at least 30%.

  17. Vorticity confinement technique for drag prediction

    Science.gov (United States)

    Povitsky, Alex; Snyder, Troy

    2011-11-01

    This work couples wake-integral drag prediction and vorticity confinement technique (VC) for the improved prediction of drag from CFD simulations. Induced drag computations of a thin wing are shown to be more accurate than the more widespread method of surface pressure integration when compared to theoretical lifting-line value. Furthermore, the VC method improves trailing vortex preservation and counteracts the shift from induced drag to numerical entropy drag with increasing distance of Trefftz plane downstream of the wing. Accurate induced drag prediction via the surface integration of pressure barring a sufficiently refined surface grid and increased computation time. Furthermore, the alternative wake-integral technique for drag prediction suffers from numerical dissipation. VC is shown to control the numerical dissipation with very modest computational overhead. The 2-D research code is used to test specific formulations of the VC body force terms and illustrate the computational efficiency of the method compared to a ``brute force'' reduction in spatial step size. For the 3-D wing simulation, ANSYS FLUENT is employed with the VC body force terms added to the solver with user-defined functions (UDFs). VC is successfully implemented to highly unsteady flows typical for Micro Air Vehicles (MAV) producing oscillative drag force either by natural vortex shedding at high angles of attack or by flapping wing motion.

  18. Determination of the surface drag coefficient

    DEFF Research Database (Denmark)

    Mahrt, L.; Vickers, D.; Sun, J.L.

    2001-01-01

    This study examines the dependence of the surface drag coefficient on stability, wind speed, mesoscale modulation of the turbulent flux and method of calculation of the drag coefficient. Data sets over grassland, sparse grass, heather and two forest sites are analyzed. For significantly unstable...... conditions, the drag coefficient does not depend systematically on z/L but decreases with wind speed for fixed intervals of z/L, where L is the Obukhov length. Even though the drag coefficient for weak wind conditions is sensitive to the exact method of calculation and choice of averaging time, the decrease...... of the drag coefficient with wind speed occurs for all of the calculation methods. A classification of flux calculation methods is constructed, which unifies the most common previous approaches. The roughness length corresponding to the usual Monin-Obukhov stability functions decreases with increasing wind...

  19. Drag Coefficient Estimation in Orbit Determination

    Science.gov (United States)

    McLaughlin, Craig A.; Manee, Steve; Lichtenberg, Travis

    2011-07-01

    Drag modeling is the greatest uncertainty in the dynamics of low Earth satellite orbits where ballistic coefficient and density errors dominate drag errors. This paper examines fitted drag coefficients found as part of a precision orbit determination process for Stella, Starlette, and the GEOSAT Follow-On satellites from 2000 to 2005. The drag coefficients for the spherical Stella and Starlette satellites are assumed to be highly correlated with density model error. The results using MSIS-86, NRLMSISE-00, and NRLMSISE-00 with dynamic calibration of the atmosphere (DCA) density corrections are compared. The DCA corrections were formulated for altitudes of 200-600 km and are found to be inappropriate when applied at 800 km. The yearly mean fitted drag coefficients are calculated for each satellite for each year studied. The yearly mean drag coefficients are higher for Starlette than Stella, where Starlette is at a higher altitude. The yearly mean fitted drag coefficients for all three satellites decrease as solar activity decreases after solar maximum.

  20. Modelling of Aerodynamic Drag in Alpine Skiing

    OpenAIRE

    Elfmark, Ola

    2017-01-01

    Most of the breaking force in the speed disciplines in alpine skiing is caused by the aerodynamic drag, and a better knowledge of the drag force is therefore desirable to gain time in races. In this study a complete database of how the drag area (CDA) changes, with respect to the different body segments, was made and used to explain a complete body motion in alpine skiing. Three experiments were performed in the wind tunnel at NTNU, Trondheim. The database from a full body measurement on an a...

  1. Drag and Torque on Locked Screw Propeller

    Directory of Open Access Journals (Sweden)

    Tomasz Tabaczek

    2014-09-01

    Full Text Available Few data on drag and torque on locked propeller towed in water are available in literature. Those data refer to propellers of specific geometry (number of blades, blade area, pitch and skew of blades. The estimation of drag and torque of an arbitrary propeller considered in analysis of ship resistance or propulsion is laborious. The authors collected and reviewed test data available in the literature. Based on collected data there were developed the empirical formulae for estimation of hydrodynamic drag and torque acting on locked screw propeller. Supplementary CFD computations were carried out in order to prove the applicability of the formulae to modern moderately skewed screw propellers.

  2. Drag Reduction by Leidenfrost Vapor Layers

    KAUST Repository

    Vakarelski, Ivan Uriev

    2011-05-23

    We demonstrate and quantify a highly effective drag reduction technique that exploits the Leidenfrost effect to create a continuous and robust lubricating vapor layer on the surface of a heated solid sphere moving in a liquid. Using high-speed video, we show that such vapor layers can reduce the hydrodynamic drag by over 85%. These results appear to approach the ultimate limit of drag reduction possible by different methods based on gas-layer lubrication and can stimulate the development of related energy saving technologies.

  3. Noninvasive evaluation of nicotinic acetylcholine receptor availability in mouse brain using single-photon emission computed tomography with [123I]5IA

    International Nuclear Information System (INIS)

    Matsuura, Yuki; Ueda, Masashi; Higaki, Yusuke; Watanabe, Keiko; Habara, Shogo; Kamino, Shinichiro; Saji, Hideo; Enomoto, Shuichi

    2016-01-01

    Introduction: Nicotinic acetylcholine receptors (nAChRs) are of great interest because they are implicated in higher brain functions. Nuclear medical imaging is one of the useful techniques for noninvasive evaluation of physiological and pathological function in living subjects. Recent progress in nuclear medical imaging modalities enables the clear visualization of the organs of small rodents. Thus, translational research using nuclear medical imaging in transgenic mice has become possible and helps to elucidate human disease pathology. However, imaging of α4β2 nAChRs in the mouse brain has not yet been performed. The purpose of this study was to assess the feasibility of single-photon emission computed tomography (SPECT) with 5-[ 123 I]iodo-3-[2(S)-azetidinylmethoxy]pyridine ([ 123 I]5IA) for evaluating α4β2 nAChR availability in the mouse brain. Methods: A 60-min dynamic SPECT imaging session of α4β2 nAChRs in the mouse brain was performed. The regional distribution of radioactivity in the SPECT images was compared to the density of α4β2 nAChRs measured in an identical mouse. Alteration of nAChR density in the brains of Tg2576 mice was also evaluated. Results: The mouse brain was clearly visualized by [ 123 I]5IA-SPECT and probe accumulation was significantly inhibited by pretreatment with (−)-nicotine. The regional distribution of radioactivity in SPECT images showed a significant positive correlation with α4β2 nAChR density measured in an identical mouse brain. Moreover, [ 123 I]5IA-SPECT was able to detect the up-regulation of α4β2 nAChRs in the brains of Tg2576 transgenic mice. Conclusions: [ 123 I]5IA-SPECT imaging would be a promising tool for evaluating α4β2 nAChR availability in the mouse brain and may be useful in translational research focused on nAChR-related diseases.

  4. Microblowing Technique for Drag Reduction, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA seeks to develop technologies for aircraft drag reduction which contribute to improved aerodynamic efficiency in support of national goals for reducing fuel...

  5. The physics of orographic gravity wave drag

    Directory of Open Access Journals (Sweden)

    Miguel A C Teixeira

    2014-07-01

    Full Text Available The drag and momentum fluxes produced by gravity waves generated in flow over orography are reviewed, focusing on adiabatic conditions without phase transitions or radiation effects, and steady mean incoming flow. The orographic gravity wave drag is first introduced in its simplest possible form, for inviscid, linearized, non-rotating flow with the Boussinesq and hydrostatic approximations, and constant wind and static stability. Subsequently, the contributions made by previous authors (primarily using theory and numerical simulations to elucidate how the drag is affected by additional physical processes are surveyed. These include the effect of orography anisotropy, vertical wind shear, total and partial critical levels, vertical wave reflection and resonance, non-hydrostatic effects and trapped lee waves, rotation and nonlinearity. Frictional and boundary layer effects are also briefly mentioned. A better understanding of all of these aspects is important for guiding the improvement of drag parametrization schemes.

  6. Satellite Formation Control Using Atmospheric Drag

    National Research Council Canada - National Science Library

    Hajovsky, Blake B

    2007-01-01

    This study investigates the use of a linear quadratic terminal controller to reconfigure satellite formations using atmospheric drag actuated control while minimizing the loss of energy of the formation...

  7. Bioinspired surfaces for turbulent drag reduction.

    Science.gov (United States)

    Golovin, Kevin B; Gose, James W; Perlin, Marc; Ceccio, Steven L; Tuteja, Anish

    2016-08-06

    In this review, we discuss how superhydrophobic surfaces (SHSs) can provide friction drag reduction in turbulent flow. Whereas biomimetic SHSs are known to reduce drag in laminar flow, turbulence adds many new challenges. We first provide an overview on designing SHSs, and how these surfaces can cause slip in the laminar regime. We then discuss recent studies evaluating drag on SHSs in turbulent flow, both computationally and experimentally. The effects of streamwise and spanwise slip for canonical, structured surfaces are well characterized by direct numerical simulations, and several experimental studies have validated these results. However, the complex and hierarchical textures of scalable SHSs that can be applied over large areas generate additional complications. Many studies on such surfaces have measured no drag reduction, or even a drag increase in turbulent flow. We discuss how surface wettability, roughness effects and some newly found scaling laws can help explain these varied results. Overall, we discuss how, to effectively reduce drag in turbulent flow, an SHS should have: preferentially streamwise-aligned features to enhance favourable slip, a capillary resistance of the order of megapascals, and a roughness no larger than 0.5, when non-dimensionalized by the viscous length scale.This article is part of the themed issue 'Bioinspired hierarchically structured surfaces for green science'. © 2016 The Author(s).

  8. Measurement of drag and its cancellation

    Energy Technology Data Exchange (ETDEWEB)

    DeBra, D B; Conklin, J W, E-mail: johnwc@stanford.edu [Department of Aeronautics and Astronautics, Stanford University, Stanford, CA 94305-4035 (United States)

    2011-05-07

    The design of drag cancellation missions of the future will take advantage of the technology experience of the past. The importance of data for modeling of the atmosphere led to at least six types of measurement: (a) balloon flights, (b) missile-launched falling spheres, (c) the 'cannonball' satellites of Ken Champion with accelerometers for low-altitude drag measurement (late 1960s and early 1970s), (d) the Agena flight of LOGACS (1967), a Bell MESA accelerometer mounted on a rotating platform to spectrally shift low-frequency errors in the accelerometer, (e) a series of French low-level accelerometers (e.g. CACTUS, 1975), and (f) correction of differential accelerations for drag errors in measuring gravity gradient on a pair of satellites (GRACE, 2002). The independent invention of the drag-free satellite concept by Pugh and Lange (1964) to cancel external disturbance added implementation opportunities. Its first flight application was for ephemeris prediction improvement with the DISCOS flight (1972)-still the only extended free test mass flight. Then successful flights for reduced disturbance environment for science measurement with gyros on GP-B (2004) and for improved accuracy in geodesy and ocean studies (GOCE, 2009) each using accelerometer measurements to control the drag-canceling thrust. LISA, DECIGO, BBO and other gravity wave-measuring satellite systems will push the cancellation of drag to new levels.

  9. Measurement of drag and its cancellation

    International Nuclear Information System (INIS)

    DeBra, D B; Conklin, J W

    2011-01-01

    The design of drag cancellation missions of the future will take advantage of the technology experience of the past. The importance of data for modeling of the atmosphere led to at least six types of measurement: (a) balloon flights, (b) missile-launched falling spheres, (c) the 'cannonball' satellites of Ken Champion with accelerometers for low-altitude drag measurement (late 1960s and early 1970s), (d) the Agena flight of LOGACS (1967), a Bell MESA accelerometer mounted on a rotating platform to spectrally shift low-frequency errors in the accelerometer, (e) a series of French low-level accelerometers (e.g. CACTUS, 1975), and (f) correction of differential accelerations for drag errors in measuring gravity gradient on a pair of satellites (GRACE, 2002). The independent invention of the drag-free satellite concept by Pugh and Lange (1964) to cancel external disturbance added implementation opportunities. Its first flight application was for ephemeris prediction improvement with the DISCOS flight (1972)-still the only extended free test mass flight. Then successful flights for reduced disturbance environment for science measurement with gyros on GP-B (2004) and for improved accuracy in geodesy and ocean studies (GOCE, 2009) each using accelerometer measurements to control the drag-canceling thrust. LISA, DECIGO, BBO and other gravity wave-measuring satellite systems will push the cancellation of drag to new levels.

  10. Drag Performance of Twist Morphing MAV Wing

    Directory of Open Access Journals (Sweden)

    Ismail N.I.

    2016-01-01

    Full Text Available Morphing wing is one of latest evolution found on MAV wing. However, due to few design problems such as limited MAV wing size and complicated morphing mechanism, the understanding of its aerodynamic behaviour was not fully explored. In fact, the basic drag distribution induced by a morphing MAV wing is still remained unknown. Thus, present work is carried out to compare the drag performance between a twist morphing wing with membrane and rigid MAV wing design. A quasi-static aeroelastic analysis by using the Ansys-Fluid Structure Interaction (FSI method is utilized in current works to predict the drag performance a twist morphing MAV wing design. Based on the drag pattern study, the results exhibits that the morphing wing has a partial similarities in overall drag pattern with the baseline (membrane and rigid wing. However, based CD analysis, it shows that TM wing induced higher CD magnitude (between 25% to 82% higher than to the baseline wing. In fact, TM wing also induced the largest CD increment (about 20% to 27% among the wings. The visualization on vortex structure revealed that TM wing also produce larger tip vortex structure (compared to baseline wings which presume to promote higher induce drag component and subsequently induce its higher CD performance.

  11. Sigma1 and dopamine D2 receptor occupancy in the mouse brain after a single administration of haloperidol and two dopamine D2-like receptor ligands

    International Nuclear Information System (INIS)

    Ishiwata, Kiichi; Kawamura, Kazunori; Kobayashi, Tadayuki; Matsuno, Kiyoshi

    2003-01-01

    We investigated sigma 1 and dopamine D 2 receptor occupancy in mouse brain after a single injection of haloperidol, nemonapride, or spiperone using [ 11 C]SA4503 and [ 11 C]raclopride, respectively. Co-injection of the three compounds significantly blocked the uptake of each radioligand. Six hours later, only haloperidol blocked [ 11 C]SA4503 uptake, while all three reduced [ 11 C]raclopride uptake. Sigma 1 receptor occupancy by haloperidol was reduced to 19% at day 2 when D 2 receptor occupancy disappeared. [ 11 C]SA4503 would be applicable to the investigation of sigma 1 receptor occupancy of antispychotic drugs using PET

  12. A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors.

    Science.gov (United States)

    Blevitt, Jonathan M; Hack, Michael D; Herman, Krystal; Chang, Leon; Keith, John M; Mirzadegan, Tara; Rao, Navin L; Lebsack, Alec D; Milla, Marcos E

    2016-06-10

    5-Lipoxygenase activating protein (FLAP) plays a critical role in the metabolism of arachidonic acid to leukotriene A4, the precursor to the potent pro-inflammatory mediators leukotriene B4 and leukotriene C4 Studies with small molecule inhibitors of FLAP have led to the discovery of a drug binding pocket on the protein surface, and several pharmaceutical companies have developed compounds and performed clinical trials. Crystallographic studies and mutational analyses have contributed to a general understanding of compound binding modes. During our own efforts, we identified two unique chemical series. One series demonstrated strong inhibition of human FLAP but differential pharmacology across species and was completely inactive in assays with mouse or rat FLAP. The other series was active across rodent FLAP, as well as human and dog FLAP. Comparison of rodent and human FLAP amino acid sequences together with an analysis of a published crystal structure led to the identification of amino acid residue 24 in the floor of the putative binding pocket as a likely candidate for the observed speciation. On that basis, we tested compounds for binding to human G24A and mouse A24G FLAP mutant variants and compared the data to that generated for wild type human and mouse FLAP. These studies confirmed that a single amino acid mutation was sufficient to reverse the speciation observed in wild type FLAP. In addition, a PK/PD method was established in canines to enable preclinical profiling of mouse-inactive compounds. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  13. Hydrodynamic Drag on Streamlined Projectiles and Cavities

    KAUST Repository

    Jetly, Aditya

    2016-04-19

    The air cavity formation resulting from the water-entry of solid objects has been the subject of extensive research due to its application in various fields such as biology, marine vehicles, sports and oil and gas industries. Recently we demonstrated that at certain conditions following the closing of the air cavity formed by the initial impact of a superhydrophobic sphere on a free water surface a stable streamlined shape air cavity can remain attached to the sphere. The formation of superhydrophobic sphere and attached air cavity reaches a steady state during the free fall. In this thesis we further explore this novel phenomenon to quantify the drag on streamlined shape cavities. The drag on the sphere-cavity formation is then compared with the drag on solid projectile which were designed to have self-similar shape to that of the cavity. The solid projectiles of adjustable weight were produced using 3D printing technique. In a set of experiments on the free fall of projectile we determined the variation of projectiles drag coefficient as a function of the projectiles length to diameter ratio and the projectiles specific weight, covering a range of intermediate Reynolds number, Re ~ 104 – 105 which are characteristic for our streamlined cavity experiments. Parallel free fall experiment with sphere attached streamlined air cavity and projectile of the same shape and effective weight clearly demonstrated the drag reduction effect due to the stress-free boundary condition at cavity liquid interface. The streamlined cavity experiments can be used as the upper bound estimate of the drag reduction by air layers naturally sustained on superhydrophobic surfaces in contact with water. In the final part of the thesis we design an experiment to test the drag reduction capacity of robust superhydrophobic coatings deposited on the surface of various model vessels.

  14. Virtual Photon Contribution to Frictional Drag in Double-layer Devices

    DEFF Research Database (Denmark)

    Donarini, Andrea; Ferrari, R.; Jauho, Antti-Pekka

    2003-01-01

    Frictional drag between coupled two-dimensional charge systems is commonly viewed as a second order effect arising either from screened Coulomb interaction, or phonon exchange. We point out that for single-photon exchange the first order contribution does not have to vanish even at T = 0, and eva......Frictional drag between coupled two-dimensional charge systems is commonly viewed as a second order effect arising either from screened Coulomb interaction, or phonon exchange. We point out that for single-photon exchange the first order contribution does not have to vanish even at T = 0...

  15. Drag Reduction by Laminar Flow Control

    Directory of Open Access Journals (Sweden)

    Nils Beck

    2018-01-01

    Full Text Available The Energy System Transition in Aviation research project of the Aeronautics Research Center Niedersachsen (NFL searches for potentially game-changing technologies to reduce the carbon footprint of aviation by promoting and enabling new propulsion and drag reduction technologies. The greatest potential for aerodynamic drag reduction is seen in laminar flow control by boundary layer suction. While most of the research so far has been on partial laminarization by application of Natural Laminar Flow (NLF and Hybrid Laminar Flow Control (HLFC to wings, complete laminarization of wings, tails and fuselages promises much higher gains. The potential drag reduction and suction requirements, including the necessary compressor power, are calculated on component level using a flow solver with viscid/inviscid coupling and a 3D Reynolds-Averaged Navier-Stokes (RANS solver. The effect on total aircraft drag is estimated for a state-of-the-art mid-range aircraft configuration using preliminary aircraft design methods, showing that total cruise drag can be halved compared to today’s turbulent aircraft.

  16. Geodetic precession or dragging of inertial frames?

    International Nuclear Information System (INIS)

    Ashby, N.; Shahid-Saless, B.

    1990-01-01

    In metric theories of gravity the principle of general covariance allows one to describe phenomena by means of any convenient choice of coordinate system. In this paper it is shown that in an appropriately chosen coordinate system, geodetic precession of a gyroscope orbiting a spherically symmetric, spinning mass can be recast as a Lense-Thirring frame-dragging effect without invoking spatial curvature. The origin of this reference frame moves around the source but the frame axes point in fixed directions. The drag can be interpreted to arise from the orbital angular momentum of the source around the origin of the reference frame. In this reference frame the effects of geodetic precession and Lense-Thirring drag due to intrinsic angular momentum of the source have the same origin, namely, gravitomagnetism

  17. Frictional Coulomb drag in strong magnetic fields

    DEFF Research Database (Denmark)

    Bønsager, Martin Christian; Flensberg, Karsten; Hu, Ben Yu-Kuang

    1997-01-01

    A treatment of frictional Coulomb drag between two two-dimensional electron layers in a strong perpendicular magnetic field, within the independent electron picture, is presented. Assuming fully resolved Landau levels, the linear response theory expression for the transresistivity rho(21) is eval......A treatment of frictional Coulomb drag between two two-dimensional electron layers in a strong perpendicular magnetic field, within the independent electron picture, is presented. Assuming fully resolved Landau levels, the linear response theory expression for the transresistivity rho(21...

  18. Correlated Coulomb drag in capacitively coupled quantum-dot structures

    DEFF Research Database (Denmark)

    Kaasbjerg, Kristen; Jauho, Antti-Pekka

    2016-01-01

    We study theoretically Coulomb drag in capacitively coupled quantum dots (CQDs) -- a biasdriven dot coupled to an unbiased dot where transport is due to Coulomb mediated energy transfer drag. To this end, we introduce a master-equation approach which accounts for higher-order tunneling (cotunneling......) processes as well as energy-dependent lead couplings, and identify a mesoscopic Coulomb drag mechanism driven by nonlocal multi-electron cotunneling processes. Our theory establishes the conditions for a nonzero drag as well as the direction of the drag current in terms of microscopic system parameters...... on Coulomb drag in CQD systems....

  19. The effect of sodium hydroxide on drag reduction using banana peel as a drag reduction agent

    Science.gov (United States)

    Kaur, H.; Jaafar, A.

    2018-02-01

    Drag reduction is observed as reduced frictional pressure losses under turbulent flow conditions. Drag reduction agent such as polymers can be introduced to increase the flowrate of water flowing and reduce the water accumulation in the system. Currently used polymers are synthetic polymers, which will harm our environment in excessive use of accumulation. A more environmentally-friendly drag reduction agent such as the polymer derived from natural sources or biopolymer, is then required for such purpose. As opposed to the synthetic polymers, the potential of biopolymers as drag reduction agents, especially those derived from a local plant source are not extensively explored. The drag reduction of a polymer produced from a local plant source within the turbulent regime was explored and assessed in this study using a rheometer, where a reduced a torque produced was perceived as a reduction of drag. This method proposed is less time consuming and is more practical which is producing carboxymethylcellulose from the banana peel. The cellulose powder was converted to carboxymethylcellulose (CMC) by etherification process. The carboxymethylation reaction during the synthesizing process was then optimized against the reaction temperature, reaction time and solubility. The biopolymers were then rheologically characterized, where the viscoelastic effects and the normal stresses produced by these biopolymers were utilized to further relate and explain the drag reduction phenomena. The research was structured to focus on producing the biopolymer and to assess the drag reduction ability of the biopolymer produced. The rheological behavior of the biopolymers was then analyzed based on the ability of reducing drag. The results are intended to expand the currently extremely limited experimental database. Based on the results, the biopolymer works as a good DRA.

  20. CLoNe is a new method to target single progenitors and study their progeny in mouse and chick.

    Science.gov (United States)

    García-Moreno, Fernando; Vasistha, Navneet A; Begbie, Jo; Molnár, Zoltán

    2014-04-01

    Cell lineage analysis enables us to address pivotal questions relating to: the embryonic origin of cells and sibling cell relationships in the adult body; the contribution of progenitors activated after trauma or disease; and the comparison across species in evolutionary biology. To address such fundamental questions, several techniques for clonal labelling have been developed, each with its shortcomings. Here, we report a novel method, CLoNe that is designed to work in all vertebrate species and tissues. CLoNe uses a cocktail of labelling, targeting and transposition vectors that enables targeting of specific subpopulations of progenitor types with a combination of fluorophores resulting in multifluorescence that describes multiple clones per specimen. Furthermore, transposition into the genome ensures the longevity of cell labelling. We demonstrate the robustness of this technique in mouse and chick forebrain development, and show evidence that CLoNe will be broadly applicable to study clonal relationships in different tissues and species.

  1. Publisher Correction: Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex.

    Science.gov (United States)

    Hrvatin, Sinisa; Hochbaum, Daniel R; Nagy, M Aurel; Cicconet, Marcelo; Robertson, Keiramarie; Cheadle, Lucas; Zilionis, Rapolas; Ratner, Alex; Borges-Monroy, Rebeca; Klein, Allon M; Sabatini, Bernardo L; Greenberg, Michael E

    2018-05-11

    In the version of this article initially published, the x-axis labels in Fig. 3c read Vglut, Gad1/2, Aldh1l1 and Pecam1; they should have read Vglut + , Gad1/2 + , Aldh1l1 + and Pecam1 + . In Fig. 4, the range values were missing from the color scales; they are, from left to right, 4-15, 0-15, 4-15 and 0-15 in Fig. 4a and 4-15, 4-15 and 4-8 in Fig. 4h. In the third paragraph of the main text, the phrase reading "Previous approaches have analyzed a limited number of inhibitory cell types, thus masking the full diversity of excitatory populations" should have read "Previous approaches have analyzed a limited number of inhibitory cell types and masked the full diversity of excitatory populations." In the second paragraph of Results section "Diversity of experience-regulated ERGs," the phrase reading "thus suggesting considerable divergence within the gene expression program responding to early stimuli" should have read "thus suggesting considerable divergence within the early stimulus-responsive gene expression program." In the fourth paragraph of Results section "Excitatory neuronal LRGs," the sentence reading "The anatomical organization of these cell types into sublayers, coupled with divergent transcriptional responses to a sensory stimulus, suggested previously unappreciated functional subdivisions located within the laminae of the mouse visual cortex and resembling the cytoarchitecture in higher mammals" should have read "The anatomical organization of these cell types into sublayers, coupled with divergent transcriptional responses to a sensory stimulus, suggests previously unappreciated functional subdivisions located within the laminae of the mouse visual cortex, resembling the cytoarchitecture in higher mammals." In the last sentence of the Results, "sensory-responsive genes" should have read "sensory-stimulus-responsive genes." The errors have been corrected in the HTML and PDF versions of the article.

  2. Repression of multiple CYP2D genes in mouse primary hepatocytes with a single siRNA construct.

    Science.gov (United States)

    Elraghy, Omaima; Baldwin, William S

    2015-01-01

    The Cyp2d subfamily is the second most abun-dant subfamily of hepatic drug-metabolizing CYPs. In mice, there are nine Cyp2d members that are believed to have redundant catalytic activity. We are testing and optimizing the ability of one short interfering RNA (siRNA) construct to knockdown the expression of multiple mouse Cyp2ds in primary hepatocytes. Expression of Cyp2d10, Cyp2d11, Cyp2d22, and Cyp2d26 was observed in the primary male mouse hepatocytes. Cyp2d9, which is male-specific and growth hormone-dependent, was not expressed in male primary hepatocytes, potentially because of its dependence on pulsatile growth hormone release from the anterior pituitary. Several different siRNAs at different concentrations and with different reagents were used to knockdown Cyp2d expression. siRNA constructs designed to repress only one construct often mildly repressed several Cyp2d isoforms. A construct designed to knockdown every Cyp2d isoform provided the best results, especially when incubated with transfection reagents designed specifically for primary cell culture. Interestingly, a construct designed to knockdown all Cyp2d isoforms, except Cyp2d10, caused a 2.5× increase in Cyp2d10 expression, presumably because of a compensatory response. However, while RNA expression is repressed 24 h after siRNA treatment, associated changes in Cyp2d-mediated metabolism are tenuous. Overall, this study provides data on the expression of murine Cyp2ds in primary cell lines, valuable information on designing siRNAs for silencing multiple murine CYPs, and potential pros and cons of using siRNA as a tool for repressing Cyp2d and estimating Cyp2d's role in murine xenobiotic metabolism.

  3. Magnetic Viscous Drag for Friction Labs

    Science.gov (United States)

    Gaffney, Chris; Catching, Adam

    2016-01-01

    The typical friction lab performed in introductory mechanics courses is usually not the favorite of either the student or the instructor. The measurements are not all that easy to make, and reproducibility is usually a troublesome issue. This paper describes the augmentation of such a friction lab with a study of the viscous drag on a magnet…

  4. High accuracy satellite drag model (HASDM)

    Science.gov (United States)

    Storz, Mark F.; Bowman, Bruce R.; Branson, Major James I.; Casali, Stephen J.; Tobiska, W. Kent

    The dominant error source in force models used to predict low-perigee satellite trajectories is atmospheric drag. Errors in operational thermospheric density models cause significant errors in predicted satellite positions, since these models do not account for dynamic changes in atmospheric drag for orbit predictions. The Air Force Space Battlelab's High Accuracy Satellite Drag Model (HASDM) estimates and predicts (out three days) a dynamically varying global density field. HASDM includes the Dynamic Calibration Atmosphere (DCA) algorithm that solves for the phases and amplitudes of the diurnal and semidiurnal variations of thermospheric density near real-time from the observed drag effects on a set of Low Earth Orbit (LEO) calibration satellites. The density correction is expressed as a function of latitude, local solar time and altitude. In HASDM, a time series prediction filter relates the extreme ultraviolet (EUV) energy index E10.7 and the geomagnetic storm index ap, to the DCA density correction parameters. The E10.7 index is generated by the SOLAR2000 model, the first full spectrum model of solar irradiance. The estimated and predicted density fields will be used operationally to significantly improve the accuracy of predicted trajectories for all low-perigee satellites.

  5. Judicial civil procedure dragging out in Kosovo

    Directory of Open Access Journals (Sweden)

    Rrustem Qehaja

    2016-03-01

    Full Text Available This article tends to deal with one of the most worrying issues in the judicial system of Kosovo the problem of judicial civil procedure dragging out. The article analyses the reasons of these dragging outs of the judicial civil procedure focusing on the context of one of the basic procedural principles in civil procedure-the principle of economy or efficiency in the courts. Dragging out of civil procedure in Kosovo has put in question not only the basic principles of civil procedure, but it also challenges the general principles related to human rights and freedoms sanctioned not only by the highest legal act of the country, but also with international treaties. The article tends to give a reflection to the most important reasons that effect and influence in these dragging outs of civil procedure, as well as, at the same time aims to give the necessary alternatives to pass through them by identifying dilemmas within the judicial practice. As a result, the motives of this scientific paper are exactly focused at the same time on identifying the dilemmas, as well as presenting ideas, to overstep them, including the judicial practice of the European Court of Human Rights on Article 6 of the European Convention on Human Rights, by which it is given the possibility to offering people efficient and within a reasonable time legal protection of their rights before national courts. For these reasons, the paper elaborates this issue based on both, the legal theory and judicial practice.

  6. Measurements of drag and flow over biofilm

    Science.gov (United States)

    Hartenberger, Joel; Gose, James W.; Perlin, Marc; Ceccio, Steven L.

    2017-11-01

    Microbial `slime' biofilms detrimentally affect the performance of every day systems from medical devices to large ocean-going vessels. In flow applications, the presence of biofilm typically results in a drag increase and may alter the turbulence in the adjacent boundary layer. Recent studies emphasize the severity of the drag penalty associated with soft biofouling and suggest potential mechanisms underlying the increase; yet, fundamental questions remain-such as the role played by compliance and the contribution of form drag to the overall resistance experienced by a fouled system. Experiments conducted on live biofilm and 3D printed rigid replicas in the Skin-Friction Flow Facility at the University of Michigan seek to examine these factors. The hydrodynamic performance of the biofilms grown on test panels was evaluated through pressure drop measurements as well as conventional and microscale PIV. High-resolution, 3D rigid replicas of select cases were generated via additive manufacturing using surface profiles obtained from a laser scanning system. Drag and flow measurements will be presented along with details of the growth process and the surface profile characterization method.

  7. Drag Reducing and Cavitation Resistant Coatings

    Energy Technology Data Exchange (ETDEWEB)

    Pease, Leonard F.

    2016-12-28

    Client, Green Building Systems (GBS), presented PNNL a coating reported to reduce drag and prevent cavitation damage on marine vessels, turbines and pumps. The composition of the coating remains proprietary but has as constituents including silicon oxides, aliphatic carbon chains, and fluorine rich particles. The coating is spray applied to surfaces. Prior GBS testing and experiments suggest reduction of both drag and cavitation on industrial scale propellers, but the underlying mechanism for these effects remains unclear. Yet, the application is compelling because even modest reductions in drag to marine vessels and cavitation to propellers and turbines present a significant economic and environmental opportunity. To discern among possible mechanisms, PNNL considered possible mechanisms with the client, executed multiple experiments, and completed one theoretical analysis (see appendix). The remainder of this report first considers image analysis to gain insight into drag reduction mechanisms and then exposes the coating to cavitation to explore its response to an intensely cavitating environment. Although further efforts may be warranted to confirm mechanisms, this report presents a first investigation into these coatings within the scope and resources of the technology assistance program (TAP).

  8. Drag coefficient Variability and Thermospheric models

    Science.gov (United States)

    Moe, Kenneth

    Satellite drag coefficients depend upon a variety of factors: The shape of the satellite, its altitude, the eccentricity of its orbit, the temperature and mean molecular mass of the ambient atmosphere, and the time in the sunspot cycle. At altitudes where the mean free path of the atmospheric molecules is large compared to the dimensions of the satellite, the drag coefficients can be determined from the theory of free-molecule flow. The dependence on altitude is caused by the concentration of atomic oxygen which plays an important role by its ability to adsorb on the satellite surface and thereby affect the energy loss of molecules striking the surface. The eccentricity of the orbit determines the satellite velocity at perigee, and therefore the energy of the incident molecules relative to the energy of adsorption of atomic oxygen atoms on the surface. The temperature of the ambient atmosphere determines the extent to which the random thermal motion of the molecules influences the momentum transfer to the satellite. The time in the sunspot cycle affects the ambient temperature as well as the concentration of atomic oxygen at a particular altitude. Tables and graphs will be used to illustrate the variability of drag coefficients. Before there were any measurements of gas-surface interactions in orbit, Izakov and Cook independently made an excellent estimate that the drag coefficient of satellites of compact shape would be 2.2. That numerical value, independent of altitude, was used by Jacchia to construct his model from the early measurements of satellite drag. Consequently, there is an altitude dependent bias in the model. From the sparce orbital experiments that have been done, we know that the molecules which strike satellite surfaces rebound in a diffuse angular distribution with an energy loss given by the energy accommodation coefficient. As more evidence accumulates on the energy loss, more realistic drag coefficients are being calculated. These improved drag

  9. Correlated Coulomb Drag in Capacitively Coupled Quantum-Dot Structures.

    Science.gov (United States)

    Kaasbjerg, Kristen; Jauho, Antti-Pekka

    2016-05-13

    We study theoretically Coulomb drag in capacitively coupled quantum dots (CQDs)-a bias-driven dot coupled to an unbiased dot where transport is due to Coulomb mediated energy transfer drag. To this end, we introduce a master-equation approach that accounts for higher-order tunneling (cotunneling) processes as well as energy-dependent lead couplings, and identify a mesoscopic Coulomb drag mechanism driven by nonlocal multielectron cotunneling processes. Our theory establishes the conditions for a nonzero drag as well as the direction of the drag current in terms of microscopic system parameters. Interestingly, the direction of the drag current is not determined by the drive current, but by an interplay between the energy-dependent lead couplings. Studying the drag mechanism in a graphene-based CQD heterostructure, we show that the predictions of our theory are consistent with recent experiments on Coulomb drag in CQD systems.

  10. Significance of relative velocity in drag force or drag power estimation for a tethered float

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.; Sastry, J.S.

    There is difference in opinion regarding the use of relative velocity instead of particle velocity alone in the estimation of drag force or power. In the present study, a tethered spherical float which undergoes oscillatory motion in regular waves...

  11. Performance of single and multi-atlas based automated landmarking methods compared to expert annotations in volumetric microCT datasets of mouse mandibles.

    Science.gov (United States)

    Young, Ryan; Maga, A Murat

    2015-01-01

    Here we present an application of advanced registration and atlas building framework DRAMMS to the automated annotation of mouse mandibles through a series of tests using single and multi-atlas segmentation paradigms and compare the outcomes to the current gold standard, manual annotation. Our results showed multi-atlas annotation procedure yields landmark precisions within the human observer error range. The mean shape estimates from gold standard and multi-atlas annotation procedure were statistically indistinguishable for both Euclidean Distance Matrix Analysis (mean form matrix) and Generalized Procrustes Analysis (Goodall F-test). Further research needs to be done to validate the consistency of variance-covariance matrix estimates from both methods with larger sample sizes. Multi-atlas annotation procedure shows promise as a framework to facilitate truly high-throughput phenomic analyses by channeling investigators efforts to annotate only a small portion of their datasets.

  12. Vehicle wheel drag coefficient in relation to travelling velocity - CFD analysis

    Science.gov (United States)

    Leśniewicz, P.; Kulak, M.; Karczewski, M.

    2016-10-01

    In order to understand the aerodynamic losses associated with a rotating automobile wheel, a detailed characteristics of the drag coefficient in relation to the applied velocity are necessary. Single drag coefficient value is most often reported for the commercially available vehicles, much less is revealed about the influence of particular car components on the energy consumption in various driving cycles. However, detailed flow potential losses determination is desired for performance estimation. To address these needs, the numerical investigation of an isolated wheel is proposed herein.

  13. AERODYNAMICS ASSESSMENT USING CFD FOR A LOW DRAG SHELL ECO-MARATHON CAR

    OpenAIRE

    Abo-Serie, E.

    2017-01-01

    Having a small car running with low power can be achieved byreducing the aerodynamics drag, rolling resistance and mechanical frictionsbetween the moving parts. The Shell Eco-Marathon competition held around theworld with events in Europe, USA and Asia shows every year new techniques andideas to reduce the power needed to drive the car. The record of over 3400 kmon the equivalent of a single litre of fuel is an indication of how car can runefficiently. The problem with these low drag cars is ...

  14. Drag force, drag torque, and Magnus force coefficients of rotating spherical particle moving in fluid

    Czech Academy of Sciences Publication Activity Database

    Lukerchenko, Nikolay; Kvurt, Y.; Keita, Ibrahima; Chára, Zdeněk; Vlasák, Pavel

    2012-01-01

    Roč. 30, č. 1 (2012), s. 55-67 ISSN 0272-6351 R&D Projects: GA AV ČR IAA200600603; GA ČR GA103/09/1718 Institutional research plan: CEZ:AV0Z20600510 Keywords : drag force * drag torque * Magnus force * Reynolds number * rotational Reynolds number Subject RIV: BK - Fluid Dynamics Impact factor: 0.435, year: 2012

  15. On the Drag Effect of a Refuelling Pellet

    DEFF Research Database (Denmark)

    Chang, Tinghong; Michelsen, Poul

    1981-01-01

    A refueling pellet is subjected mainly to two kinds of drags: (1) inertial drag caused by the motion of the pellet relative to the surrounding plasma, and (2) ablation drag caused by an uneven ablation rate of the front and the rear surface of the pellet in an inhomogeneous plasma. Computational ...... results showed that for reasonable combinations of pellet size and injection speed, the drag effect is hardly detectable for plasma conditions prevailing in current large tokamaks....

  16. Lift, drag, and guidance forces on alternating polarity magnets, using loop guideways

    International Nuclear Information System (INIS)

    Lindenbaum, S.D.; Lee, M.S.

    1975-01-01

    Exact solutions of track current, lift force, and drag force, together with their velocity dependence, have been computed for a vehicle carrying a finite number of fixed current alternating polarity superconducting magnets, suspended at various heights over structured track guideways of the single- and double-loop (''null'') types. Results for the double-loop case are compared with those of a previously reported approximate analysis. The analytical method is then applied to a study of a low-drag guidance loop guideway which is integrable with lift loop guideways utilizing a common set of vehicle magnets. Solutions are obtained for guidance track restoring forces, lateral destabilization forces, and lift force degradation as functions of lateral displacement from symmetry. The dependence of lift, drag, and lift-to-drag on track loop parameters is studied and the linear dependence of lift-to-drag on loop time constant confirmed. The contribution to the forces made by successive addition of alternating polarity magnets is calculated and the marked reduction in lift force pulsation noted

  17. Aerodynamic drag reduction by vertical splitter plates

    Science.gov (United States)

    Gilliéron, Patrick; Kourta, Azeddine

    2010-01-01

    The capacity of vertical splitter plates placed at the front or the rear of a simplified car geometry to reduce drag, with and without skew angle, is investigated for Reynolds numbers between 1.0 × 106 and 1.6 × 106. The geometry used is a simplified geometry to represent estate-type vehicles, for the rear section, and MPV-type vehicle. Drag reductions of nearly 28% were obtained for a zero skew angle with splitter plates placed at the front of models of MPV or utility vehicles. The results demonstrate the advantage of adapting the position and orientation of the splitter plates in the presence of a lateral wind. All these results confirm the advantage of this type of solution, and suggest that this expertise should be used in the automotive field to reduce consumption and improve dynamic stability of road vehicles.

  18. Aerodynamic drag reduction by vertical splitter plates

    Energy Technology Data Exchange (ETDEWEB)

    Gillieron, Patrick [Renault Group, Research Division, Fluid Mechanics and Aerodynamics, Guyancourt (France); Kourta, Azeddine [Polytech' Orleans, Institut PRISME, ESA, Orleans (France)

    2010-01-15

    The capacity of vertical splitter plates placed at the front or the rear of a simplified car geometry to reduce drag, with and without skew angle, is investigated for Reynolds numbers between 1.0 x 10{sup 6} and 1.6 x 10{sup 6}. The geometry used is a simplified geometry to represent estate-type vehicles, for the rear section, and MPV-type vehicle. Drag reductions of nearly 28% were obtained for a zero skew angle with splitter plates placed at the front of models of MPV or utility vehicles. The results demonstrate the advantage of adapting the position and orientation of the splitter plates in the presence of a lateral wind. All these results confirm the advantage of this type of solution, and suggest that this expertise should be used in the automotive field to reduce consumption and improve dynamic stability of road vehicles. (orig.)

  19. Switchable and Tunable Aerodynamic Drag on Cylinders

    Science.gov (United States)

    Guttag, Mark; Lopéz Jiménez, Francisco; Upadhyaya, Priyank; Kumar, Shanmugam; Reis, Pedro

    We report results on the performance of Smart Morphable Surfaces (Smporhs) that can be mounted onto cylindrical structures to actively reduce their aerodynamic drag. Our system comprises of an elastomeric thin shell with a series of carefully designed subsurface cavities that, once depressurized, lead to a dramatic deformation of the surface topography, on demand. Our design is inspired by the morphology of the giant cactus (Carnegiea gigantea) which possesses an array of axial grooves, thought to help reduce aerodynamic drag, thereby enhancing the structural robustness of the plant under wind loading. We perform systematic wind tunnel tests on cylinders covered with our Smorphs and characterize their aerodynamic performance. The switchable and tunable nature of our system offers substantial advantages for aerodynamic performance when compared to static topographies, due to their operation over a wider range of flow conditions.

  20. Radiation-induced DNA single-strand scission and its rejoining in spermatogonia and spermatozoa of mouse

    International Nuclear Information System (INIS)

    Ono, T.; Okada, S.

    1977-01-01

    Gamma-ray-induced DNA single-strand scissions and the ability to repair the scissions in spermatogonia from young mice and in spermatozoa from adult mice were studied quantitatively by an alkaline sucrose density-gradient centrifugation method. The average size of DNAs in non-irradiated spermatogonia was 2.6-3.0xx10 8 daltons, similar to those of a spermatid-rich population, and the size of DNA in non-irradiated spermatozoa was 1.2x10 8 daltons. In spermatogonia, the radiosensitivity of DNA was 0.42 single-strand breaks/10 12 daltons of DNA/rad in oxic conditions and only 0.24 under anoxic conditions. In spermatozoa the break efficiency of DNA was 0.22 single-strand breaks/10 12 daltons of DNA/rad under oxic conditions and altered little under anoxic irradiation. The DNA scissions were efficiently repaired in spermatogonia within 10 min, whereas the breaks in spermatozoa were not rejoined at all even after two days of post-irradiation time. The radiosensitivities of DNA, repair capability and non- and/or slowreparable DNA scissions were compared in spermatogonium-rich, spermatid-rich and spermatozoanrich populations

  1. Quantitative evaluation of a single-distance phase-retrieval method applied on in-line phase-contrast images of a mouse lung

    International Nuclear Information System (INIS)

    Mohammadi, Sara; Larsson, Emanuel; Alves, Frauke; Dal Monego, Simeone; Biffi, Stefania; Garrovo, Chiara; Lorenzon, Andrea; Tromba, Giuliana; Dullin, Christian

    2014-01-01

    Quantitative analysis concerning the application of a single-distance phase-retrieval algorithm on in-line phase-contrast images of a mouse lung at different sample-to-detector distances is presented. Propagation-based X-ray phase-contrast computed tomography (PBI) has already proven its potential in a great variety of soft-tissue-related applications including lung imaging. However, the strong edge enhancement, caused by the phase effects, often hampers image segmentation and therefore the quantitative analysis of data sets. Here, the benefits of applying single-distance phase retrieval prior to the three-dimensional reconstruction (PhR) are discussed and quantified compared with three-dimensional reconstructions of conventional PBI data sets in terms of contrast-to-noise ratio (CNR) and preservation of image features. The PhR data sets show more than a tenfold higher CNR and only minor blurring of the edges when compared with PBI in a predominately absorption-based set-up. Accordingly, phase retrieval increases the sensitivity and provides more functionality in computed tomography imaging

  2. Simulating Electrophoresis with Discrete Charge and Drag

    Science.gov (United States)

    Mowitz, Aaron J.; Witten, Thomas A.

    A charged asymmetric rigid cluster of colloidal particles in saline solution can respond in exotic ways to an electric field: it may spin or move transversely. These distinctive motions arise from the drag force of the neutralizing countercharge surrounding the cluster. Because of this drag, calculating the motion of arbitrary asymmetric objects with nonuniform charge is impractical by conventional methods. Here we present a new method of simulating electrophoresis, in which we replace the continuous object and the surrounding countercharge with discrete point-draggers, called Stokeslets. The balance of forces imposes a linear, self-consistent relation among the drag and Coulomb forces on the Stokeslets, which allows us to easily determine the object's motion via matrix inversion. By explicitly enforcing charge+countercharge neutrality, the simulation recovers the distinctive features of electrophoretic motion to few-percent accuracy using as few as 1000 Stokeslets. In particular, for uniformly charged objects, we observe the characteristic Smoluchowski independence of mobility on object size and shape. We then discuss electrophoretic motion of asymmetric objects, where our simulation method is particularly advantageous. This work is supported by a Grant from the US-Israel Binational Science Foundation.

  3. Drag reduction by a polymeric aluminium soap

    Energy Technology Data Exchange (ETDEWEB)

    Rodriquez, F.

    1971-04-12

    The pressure drop per unit length of pipe during the turbulent flow of liquids is reduced by certain additives. Most such drag reducing or friction-reducing agents are polymers of very high molecular weight. Some time ago, aluminum soaps were described as reducing drag in organic solvents, but the viscosity in laminar flow of such solutions was much higher than that of the solvents. More recently, it was found that aluminum dioleate and aluminum palmitate did not reduce turbulent friction until the solute concentration reached 0.75%. The viscosity at this concentration was 2 or 3 times that of the solvent, benzene. Exploratory work with aluminum di-2-ethylhexanoate indicates that it is an effective drag-reducing agent at concentrations which increase the viscosity of toluene by less than 10%. The dependence of the effectiveness on concentration is similar to that of most polymers. Taking into account the normal change in friction factor with Reynolds number together with end effects in the apparatus, the maximum effectiveness (x = 54 cm) corresponds to a a decrease in friction factor to less than a quarter of the original value for toluene alone. (13 refs.)

  4. Single systemic administration of Ag85B of mycobacteria DNA inhibits allergic airway inflammation in a mouse model of asthma

    Directory of Open Access Journals (Sweden)

    Karamatsu K

    2012-12-01

    Full Text Available Katsuo Karamatsu,1,2 Kazuhiro Matsuo,3 Hiroyasu Inada,4 Yusuke Tsujimura,1 Yumiko Shiogama,1,2 Akihiro Matsubara,1,2 Mitsuo Kawano,5 Yasuhiro Yasutomi1,21Laboratory of Immunoregulation and Vaccine Research, Tsukuba Primate Research Center, National Institute of Biomedical Innovation, Tsukuba, 2Division of Immunoregulation, Department of Molecular and Experimental Medicine, Mie University Graduate School of Medicine, Tsu, 3Department of Research and Development, Japan BCG Laboratory, Tokyo, 4Department of Pathology, Suzuka University of Medical Science, Suzuka, 5Department of Microbiology and Molecular Genetics, Mie University Graduate School of Medicine, Tsu, JapanAbstract: The immune responses of T-helper (Th and T-regulatory cells are thought to play a crucial role in the pathogenesis of allergic airway inflammation observed in asthma. The correction of immune response by these cells should be considered in the prevention and treatment of asthma. Native antigen 85B (Ag85B of mycobacteria, which cross-reacts among mycobacteria species, may play an important biological role in host–pathogen interaction since it elicits various immune responses by activation of Th cells. The current study investigated the antiallergic inflammatory effects of DNA administration of Ag85B from Mycobacterium kansasii in a mouse model of asthma. Immunization of BALB/c mice with alum-adsorbed ovalbumin followed by aspiration with aerosolized ovalbumin resulted in the development of allergic airway inflammation. Administration of Ag85B DNA before the aerosolized ovalbumin challenge protected the mice from subsequent induction of allergic airway inflammation. Serum and bronchoalveolar lavage immunoglobulin E levels, extent of eosinophil infiltration, and levels of Th2-type cytokines in Ag85B DNA-administered mice were significantly lower than those in control plasmid-immunized mice, and levels of Th1- and T-regulatory-type cytokines were enhanced by Ag85B

  5. Single cell electroporation for longitudinal imaging of synaptic structure and function in the adult mouse neocortex in vivo

    Directory of Open Access Journals (Sweden)

    Stephane ePages

    2015-04-01

    Full Text Available Longitudinal imaging studies of neuronal structures in vivo have revealed rich dynamics in dendritic spines and axonal boutons. Spines and boutons are considered to be proxies for synapses. This implies that synapses display similar dynamics. However, spines and boutons do not always bear synapses, some may contain more than one, and dendritic shaft synapses have no clear structural proxies. In addition, synaptic strength is not always accurately revealed by just the size of these structures. Structural and functional dynamics of synapses could be studied more reliably using fluorescent synaptic proteins as markers for size and function. These proteins are often large and possibly interfere with circuit development, which renders them less suitable for conventional transfection or transgenesis methods such as viral vectors, in utero electroporation and germline transgenesis. Single cell electroporation has been shown to be a potential alternative for transfection of recombinant fluorescent proteins in adult cortical neurons. Here we provide proof of principle for the use of single cell electroporation to express and subsequently image fluorescently tagged synaptic proteins over days to weeks in vivo.

  6. Thermospheric density and satellite drag modeling

    Science.gov (United States)

    Mehta, Piyush Mukesh

    The United States depends heavily on its space infrastructure for a vast number of commercial and military applications. Space Situational Awareness (SSA) and Threat Assessment require maintaining accurate knowledge of the orbits of resident space objects (RSOs) and the associated uncertainties. Atmospheric drag is the largest source of uncertainty for low-perigee RSOs. The uncertainty stems from inaccurate modeling of neutral atmospheric mass density and inaccurate modeling of the interaction between the atmosphere and the RSO. In order to reduce the uncertainty in drag modeling, both atmospheric density and drag coefficient (CD) models need to be improved. Early atmospheric density models were developed from orbital drag data or observations of a few early compact satellites. To simplify calculations, densities derived from orbit data used a fixed CD value of 2.2 measured in a laboratory using clean surfaces. Measurements from pressure gauges obtained in the early 1990s have confirmed the adsorption of atomic oxygen on satellite surfaces. The varying levels of adsorbed oxygen along with the constantly changing atmospheric conditions cause large variations in CD with altitude and along the orbit of the satellite. Therefore, the use of a fixed CD in early development has resulted in large biases in atmospheric density models. A technique for generating corrections to empirical density models using precision orbit ephemerides (POE) as measurements in an optimal orbit determination process was recently developed. The process generates simultaneous corrections to the atmospheric density and ballistic coefficient (BC) by modeling the corrections as statistical exponentially decaying Gauss-Markov processes. The technique has been successfully implemented in generating density corrections using the CHAMP and GRACE satellites. This work examines the effectiveness, specifically the transfer of density models errors into BC estimates, of the technique using the CHAMP and

  7. Pharmacological doses of daily ascorbate protect tumours from radiation damage after a single dose of radiation in an intracranial mouse glioma model

    Directory of Open Access Journals (Sweden)

    Carole eGrasso

    2014-12-01

    Full Text Available Pharmacological ascorbate is currently used as an anti-cancer treatment, potentially in combination with radiation therapy, by integrative medicine practitioners. In the acidic, metal-rich tumour environment, ascorbate acts as a pro-oxidant, with a mode of action similar to that of ionising radiation; both treatments kill cells predominantly by free radical-mediated DNA damage. The brain tumour, glioblastoma multiforme (GBM, is very resistant to radiation; radiosensitising GBM cells will improve survival of GBM patients. Here we demonstrate that a single fraction (6 Gy of radiation combined with a one hour exposure to ascorbate (5 mM sensitised murine glioma GL261cells to radiation in survival and colony-forming assays in vitro. In addition, we report the effect of a single fraction (4.5 Gy of whole brain radiation combined with daily intra-peritoneal injections of ascorbate (1 mg/kg in an intra-cranial GL261 glioma mouse model. Tumour-bearing C57BL/6 mice were divided into four groups: one group received a single dose of 4.5 Gy to the brain eight days after tumour implantation, a second group received daily intra-peritoneal injections of ascorbate (day 8-45 after implantation, a third group received both treatments and a fourth control group received no treatment. While radiation delayed tumour progression, intra-peritoneal ascorbate alone had no effect on tumour progression. Tumour progression was faster in tumour-bearing mice treated with radiation and daily ascorbate than those treated with radiation alone. Histological analysis showed less necrosis in tumours treated with both radiation and ascorbate, consistent with a radio-protective effect of ascorbate in vivo. Discrepancies between our in vitro and in vivo results may be explained by differences in the tumour micro-environment which determines whether ascorbate remains outside the cell, acting as a pro-oxidant or whether it enters the cells and acts as an anti-oxidant.

  8. Pharmacological doses of daily ascorbate protect tumors from radiation damage after a single dose of radiation in an intracranial mouse glioma model.

    Science.gov (United States)

    Grasso, Carole; Fabre, Marie-Sophie; Collis, Sarah V; Castro, M Leticia; Field, Cameron S; Schleich, Nanette; McConnell, Melanie J; Herst, Patries M

    2014-01-01

    Pharmacological ascorbate is currently used as an anti-cancer treatment, potentially in combination with radiation therapy, by integrative medicine practitioners. In the acidic, metal-rich tumor environment, ascorbate acts as a pro-oxidant, with a mode of action similar to that of ionizing radiation; both treatments kill cells predominantly by free radical-mediated DNA damage. The brain tumor, glioblastoma multiforme (GBM), is very resistant to radiation; radiosensitizing GBM cells will improve survival of GBM patients. Here, we demonstrate that a single fraction (6 Gy) of radiation combined with a 1 h exposure to ascorbate (5 mM) sensitized murine glioma GL261 cells to radiation in survival and colony-forming assays in vitro. In addition, we report the effect of a single fraction (4.5 Gy) of whole brain radiation combined with daily intraperitoneal injections of ascorbate (1 mg/kg) in an intracranial GL261 glioma mouse model. Tumor-bearing C57BL/6 mice were divided into four groups: one group received a single dose of 4.5 Gy to the brain 8 days after tumor implantation, a second group received daily intraperitoneal injections of ascorbate (day 8-45) after implantation, a third group received both treatments and a fourth control group received no treatment. While radiation delayed tumor progression, intraperitoneal ascorbate alone had no effect on tumor progression. Tumor progression was faster in tumor-bearing mice treated with radiation and daily ascorbate than in those treated with radiation alone. Histological analysis showed less necrosis in tumors treated with both radiation and ascorbate, consistent with a radio-protective effect of ascorbate in vivo. Discrepancies between our in vitro and in vivo results may be explained by differences in the tumor microenvironment, which determines whether ascorbate remains outside the cell, acting as a pro-oxidant, or whether it enters the cells and acts as an anti-oxidant.

  9. Drag Effect in Double-Layer Dipolar Fermi Gases

    International Nuclear Information System (INIS)

    Tanatar, B; Renklioglu, B; Oktel, M O

    2014-01-01

    We consider two parallel layers of two-dimensional spin-polarized dipolar Fermi gas without any tunneling between the layers. The effective interactions describing screening and correlation effects between the dipoles in a single layer (intra-layer) and across the layers (interlayer) are modeled within the Hubbard approximation. We calculate the rate of momentum transfer between the layers when the gas in one layer has a steady flow. The momentum transfer induces a steady flow in the second layer which is assumed initially at rest. This is the drag effect familiar from double-layer semiconductor and graphene structures. Our calculations show that the momentum relaxation time has temperature dependence similar to that in layers with charged particles which we think is related to the contributions from the collective modes of the system

  10. Evaluation of Skin Friction Drag for Liner Applications in Aircraft

    Science.gov (United States)

    Gerhold, Carl H.; Brown, Martha C.; Jasinski, Christopher M.

    2016-01-01

    A parameter that is gaining significance in the evaluation of acoustic liner performance is the skin friction drag induced by air flow over the liner surface. Estimates vary widely regarding the amount of drag the liner induces relative to a smooth wall, from less than a 20% increase to nearly 100%, and parameters such as face sheet perforate hole diameter, percent open area, and sheet thickness are expected to figure prominently in the skin friction drag. Even a small increase in liner drag can impose an economic penalty, and current research is focused on developing 'low drag' liner concepts, with the goal being to approach the skin friction drag of a smooth wall. The issue of skin friction drag takes on greater significance as airframe designers investigate the feasibility of putting sound absorbing liners on the non-lifting surfaces of the wings and fuselage, for the purpose of reducing engine noise reflected and scattered toward observers on the ground. Researchers at the NASA Langley Research Center have embarked on investigations of liner skin friction drag with the aims of: developing a systematic drag measurement capability, establishing the drag of current liners, and developing liners that produce reduced drag without compromising acoustic performance. This paper discusses the experimental procedures that have been developed to calculate the drag coefficient based on the change in momentum thickness and the companion research program being carried out to measure the drag directly using a force balance. Liner samples that are evaluated include a solid wall with known roughness and conventional liners with perforated facesheets of varying hole diameter and percent open area.

  11. Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles

    Directory of Open Access Journals (Sweden)

    Elisia D. Tichy

    2017-10-01

    Full Text Available Muscle stem cells (MuSCs contribute to muscle regeneration following injury. In many muscle disorders, the repeated cycles of damage and repair lead to stem cell dysfunction. While telomere attrition may contribute to aberrant stem cell functions, methods to accurately measure telomere length in stem cells from skeletal muscles have not been demonstrated. Here, we have optimized and validated such a method, named MuQ-FISH, for analyzing telomere length in MuSCs from either mice or humans. Our analysis showed no differences in telomere length between young and aged MuSCs from uninjured wild-type mice, but MuSCs isolated from young dystrophic mice exhibited significantly shortened telomeres. In corroboration, we demonstrated that telomere attrition is present in human dystrophic MuSCs, which underscores its importance in diseased regenerative failure. The robust technique described herein provides analysis at a single-cell resolution and may be utilized for other cell types, especially rare populations of cells.

  12. Selection of diethylstilbestrol-specific single-chain antibodies from a non-immunized mouse ribosome display library.

    Directory of Open Access Journals (Sweden)

    Yanan Sun

    Full Text Available Single chain variable fragments (scFvs against diethylstilbestrol (DES were selected from the splenocytes of non-immunized mice by ribosome display technology. A naive library was constructed and engineered to allow in vitro transcription and translation using an E. coli lysate system. Alternating selection in solution and immobilization in microtiter wells was used to pan mRNA-ribosome-antibody (ARM complexes. After seven rounds of ribosome display, the expression vector pTIG-TRX containing the selected specific scFv DNAs were transformed into Escherichia coli BL21 (DE3 for expression. Twenty-six positive clones were screened and five clones had high antibody affinity and specificity to DES as evidenced by indirect competitive ELISA. Sequence analysis showed that these five DES-specific scFvs had different amino acid sequences, but the CDRs were highly similar. Surface plasmon resonance (SPR analysis was used to determine binding kinetics of one clone (30-1. The measured K(D was 3.79 µM. These results indicate that ribosome display technology can be used to efficiently isolate hapten-specific antibody (Ab fragments from a naive library; this study provides a methodological framework for the development of novel immunoassays for multiple environmental pollutants with low molecular weight detection using recombinant antibodies.

  13. Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification.

    Science.gov (United States)

    Kokkaliaris, Konstantinos D; Drew, Erin; Endele, Max; Loeffler, Dirk; Hoppe, Philipp S; Hilsenbeck, Oliver; Schauberger, Bernhard; Hinzen, Christoph; Skylaki, Stavroula; Theodorou, Marina; Kieslinger, Matthias; Lemischka, Ihor; Moore, Kateri; Schroeder, Timm

    2016-09-01

    The maintenance of hematopoietic stem cells (HSCs) during ex vivo culture is an important prerequisite for their therapeutic manipulation. However, despite intense research, culture conditions for robust maintenance of HSCs are still missing. Cultured HSCs are quickly lost, preventing their improved analysis and manipulation. Identification of novel factors supporting HSC ex vivo maintenance is therefore necessary. Coculture with the AFT024 stroma cell line is capable of maintaining HSCs ex vivo long-term, but the responsible molecular players remain unknown. Here, we use continuous long-term single-cell observation to identify the HSC behavioral signature under supportive or nonsupportive stroma cocultures. We report early HSC survival as a major characteristic of HSC-maintaining conditions. Behavioral screening after manipulation of candidate molecules revealed that the extracellular matrix protein dermatopontin (Dpt) is involved in HSC maintenance. DPT knockdown in supportive stroma impaired HSC survival, whereas ectopic expression of the Dpt gene or protein in nonsupportive conditions restored HSC survival. Supplementing defined stroma- and serum-free culture conditions with recombinant DPT protein improved HSC clonogenicity. These findings illustrate a previously uncharacterized role of Dpt in maintaining HSCs ex vivo. © 2016 by The American Society of Hematology.

  14. Fuel Savings and Aerodynamic Drag Reduction from Rail Car Covers

    Science.gov (United States)

    Storms, Bruce; Salari, Kambiz; Babb, Alex

    2008-01-01

    The potential for energy savings by reducing the aerodynamic drag of rail cars is significant. A previous study of aerodynamic drag of coal cars suggests that a 25% reduction in drag of empty cars would correspond to a 5% fuel savings for a round trip [1]. Rail statistics for the United States [2] report that approximately 5.7 billion liters of diesel fuel were consumed for coal transportation in 2002, so a 5% fuel savings would total 284 million liters. This corresponds to 2% of Class I railroad fuel consumption nationwide. As part of a DOE-sponsored study, the aerodynamic drag of scale rail cars was measured in a wind tunnel. The goal of the study was to measure the drag reduction of various rail-car cover designs. The cover designs tested yielded an average drag reduction of 43% relative to empty cars corresponding to an estimated round-trip fuel savings of 9%.

  15. Engineering drag currents in Coulomb coupled quantum dots

    Science.gov (United States)

    Lim, Jong Soo; Sánchez, David; López, Rosa

    2018-02-01

    The Coulomb drag phenomenon in a Coulomb-coupled double quantum dot system is revisited with a simple model that highlights the importance of simultaneous tunneling of electrons. Previously, cotunneling effects on the drag current in mesoscopic setups have been reported both theoretically and experimentally. However, in both cases the sequential tunneling contribution to the drag current was always present unless the drag level position were too far away from resonance. Here, we consider the case of very large Coulomb interaction between the dots, whereby the drag current needs to be assisted by cotunneling events. As a consequence, a quantum coherent drag effect takes place. Further, we demonstrate that by properly engineering the tunneling probabilities using band tailoring it is possible to control the sign of the drag and drive currents, allowing them to flow in parallel or antiparallel directions. We also show that the drag current can be manipulated by varying the drag gate potential and is thus governed by electron- or hole-like transport.

  16. Drag reduction through self-texturing compliant bionic materials

    OpenAIRE

    Eryong Liu; Longyang Li; Gang Wang; Zhixiang Zeng; Wenjie Zhao; Qunji Xue

    2017-01-01

    Compliant fish skin is effectively in reducing drag, thus the design and application of compliant bionic materials may be a good choice for drag reduction. Here we consider the drag reduction of compliant bionic materials. First, ZnO and PDMS mesh modified with n-octadecane were prepared, the drag reduction of self-texturing compliant n-octadecane were studied. The results show that the mesh modified by ZnO and PDMS possess excellent lipophilic and hydrophobic, thus n-octadecane at solid, sem...

  17. On the origin of the drag force on golf balls

    Science.gov (United States)

    Balaras, Elias; Beratlis, Nikolaos; Squires, Kyle

    2017-11-01

    It is well establised that dimples accelerate the drag-crisis on a sphere. The result of the early drag-crisis is a reduction of the drag coefficient by more than a factor of two when compared to a smooth sphere at the same Reynolds number. However, when the drag coefficients for smooth and dimpled spheres in the supercritical regime are compared, the latter is higher by a factor of two to three. To understand the origin of this behavior we conducted direct numerical simulations of the flow around a dimpled sphere, which is similar to commercially available golf balls, in the supercritical regime. By comparing the results to those for a smooth sphere it is found that dimples, although effective in accelerating the drag crisis, impose a local drag-penalty, which contributes significantly to the overall drag force. This finding challenges the broadly accepted view, that the dimples only indirectly affect the drag force on a golf ball by manipulating the structure of the turbulent boundary layer near the wall and consequently affect global separation. Within this view, typically the penalty on the drag force imposed by the dimples is assumed to be small and coming primarily from skin friction. The direct numerical simulations we will report reveal a very different picture.

  18. Lift and Drag on Cylinder of Octagonal Cross-Section in a Turbulent Stream

    Directory of Open Access Journals (Sweden)

    Md. Jomir Hossain

    2013-12-01

    Full Text Available An experimental investigation of surface static pressure distributions on octagonal cylinder in uniform and turbulent flows was carried out. The study was performed on both the single cylinder and the group of two cylinders, two cylinders were used, one was at the upstream side, and the other was at the downstream side of the flow. They were placed centrally along the flow direction. The inter-spacing space between the two cylinders was varied at 1D, 2D, 3D, 4D, 5D, 6D, 7D and 8D, where D is the width of the cylinder across the flow direction. The pressure coefficients were calculated from the measured values of the surface static pressure distribution on the cylinder. Then the drag and lift coefficients were obtained from the pressure coefficients by the numerical integration method. It was observed that at various angles of attack, the values of the lift coefficients and drag coefficients were insignificant compared to those for a sharp-edged square cylinder. The strength of the vortex shedding was shown to be reduced as the intensity of the incident turbulence was increased. Measurements of drag at various angles of attack (0° to 40° showed that with increase in turbulence level the minimum drag occurred at smaller values of angle of attack.

  19. Drag Reduction Through Distributed Electric Propulsion

    Science.gov (United States)

    Stoll, Alex M.; Bevirt, JoeBen; Moore, Mark D.; Fredericks, William J.; Borer, Nicholas K.

    2014-01-01

    One promising application of recent advances in electric aircraft propulsion technologies is a blown wing realized through the placement of a number of electric motors driving individual tractor propellers spaced along each wing. This configuration increases the maximum lift coefficient by providing substantially increased dynamic pressure across the wing at low speeds. This allows for a wing sized near the ideal area for maximum range at cruise conditions, imparting the cruise drag and ride quality benefits of this smaller wing size without decreasing takeoff and landing performance. A reference four-seat general aviation aircraft was chosen as an exemplary application case. Idealized momentum theory relations were derived to investigate tradeoffs in various design variables. Navier-Stokes aeropropulsive simulations were performed with various wing and propeller configurations at takeoff and landing conditions to provide insight into the effect of different wing and propeller designs on the realizable effective maximum lift coefficient. Similar analyses were performed at the cruise condition to ensure that drag targets are attainable. Results indicate that this configuration shows great promise to drastically improve the efficiency of small aircraft.

  20. Effects of Increasing Drag on Conjunction Assessment

    Science.gov (United States)

    Frigm, Ryan Clayton; McKinley, David P.

    2010-01-01

    Conjunction Assessment Risk Analysis relies heavily on the computation of the Probability of Collision (Pc) and the understanding of the sensitivity of this calculation to the position errors as defined by the covariance. In Low Earth Orbit (LEO), covariance is predominantly driven by perturbations due to atmospheric drag. This paper describes the effects of increasing atmospheric drag through Solar Cycle 24 on Pc calculations. The process of determining these effects is found through analyzing solar flux predictions on Energy Dissipation Rate (EDR), historical relationship between EDR and covariance, and the sensitivity of Pc to covariance. It is discovered that while all LEO satellites will be affected by the increase in solar activity, the relative effect is more significant in the LEO regime around 700 kilometers in altitude compared to 400 kilometers. Furthermore, it is shown that higher Pc values can be expected at larger close approach miss distances. Understanding these counter-intuitive results is important to setting Owner/Operator expectations concerning conjunctions as solar maximum approaches.

  1. Young children's ability to use a computer mouse

    NARCIS (Netherlands)

    Donker, A.; Reitsma, P.

    2007-01-01

    Because there is little empirical data available on how well young children are able to use a computer mouse, the present study examined their proficiency in clicking on small objects at various positions on the screen and their skill in moving objects over the screen, using drag-and-drop and

  2. London 2012 Paralympic swimming: passive drag and the classification system.

    Science.gov (United States)

    Oh, Yim-Taek; Burkett, Brendan; Osborough, Conor; Formosa, Danielle; Payton, Carl

    2013-09-01

    The key difference between the Olympic and Paralympic Games is the use of classification systems within Paralympic sports to provide a fair competition for athletes with a range of physical disabilities. In 2009, the International Paralympic Committee mandated the development of new, evidence-based classification systems. This study aims to assess objectively the swimming classification system by determining the relationship between passive drag and level of swimming-specific impairment, as defined by the current swimming class. Data were collected on participants at the London 2012 Paralympic Games. The passive drag force of 113 swimmers (classes 3-14) was measured using an electro-mechanical towing device and load cell. Swimmers were towed on the surface of a swimming pool at 1.5 m/s while holding their most streamlined position. Passive drag ranged from 24.9 to 82.8 N; the normalised drag (drag/mass) ranged from 0.45 to 1.86 N/kg. Significant negative associations were found between drag and the swimming class (τ = -0.41, p < 0.01) and normalised drag and the swimming class (τ = -0.60, p < 0.01). The mean difference in drag between adjacent classes was inconsistent, ranging from 0 N (6 vs 7) to 11.9 N (5 vs 6). Reciprocal Ponderal Index (a measure of slenderness) correlated moderately with normalised drag (r(P) = -0.40, p < 0.01). Although swimmers with the lowest swimming class experienced the highest passive drag and vice versa, the inconsistent difference in mean passive drag between adjacent classes indicates that the current classification system does not always differentiate clearly between swimming groups.

  3. Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria.

    Science.gov (United States)

    Wijayalath, Wathsala; Majji, Sai; Villasante, Eileen F; Brumeanu, Teodor D; Richie, Thomas L; Casares, Sofia

    2014-09-30

    Malaria is a deadly infectious disease affecting millions of people in tropical and sub-tropical countries. Among the five species of Plasmodium parasites that infect humans, Plasmodium falciparum accounts for the highest morbidity and mortality associated with malaria. Since humans are the only natural hosts for P. falciparum, the lack of convenient animal models has hindered the understanding of disease pathogenesis and prompted the need of testing anti-malarial drugs and vaccines directly in human trials. Humanized mice hosting human cells represent new pre-clinical models for infectious diseases that affect only humans. In this study, the ability of human-immune-system humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice to sustain infection with P. falciparum was explored. Four week-old DRAG mice were infused with HLA-matched human haematopoietic stem cells (HSC) and examined for reconstitution of human liver cells and erythrocytes. Upon challenge with infectious P. falciparum sporozoites (NF54 strain) humanized DRAG mice were examined for liver stage infection, blood stage infection, and transmission to Anopheles stephensi mosquitoes. Humanized DRAG mice reconstituted human hepatocytes, Kupffer cells, liver endothelial cells, and erythrocytes. Upon intravenous challenge with P. falciparum sporozoites, DRAG mice sustained liver to blood stage infection (average 3-5 parasites/microlitre blood) and allowed transmission to An. stephensi mosquitoes. Infected DRAG mice elicited antibody and cellular responses to the blood stage parasites and self-cured the infection by day 45 post-challenge. DRAG mice represent the first human-immune-system humanized mouse model that sustains the complex vertebrate life cycle of P. falciparum without the need of exogenous injection of human hepatocytes/erythrocytes or P. falciparum parasite adaptation. The ability of DRAG mice to elicit specific human immune responses to P. falciparum parasites may help deciphering immune correlates

  4. Screening for single-chain variable fragment antibodies against multiple Cry1 toxins from an immunized mouse phage display antibody library.

    Science.gov (United States)

    Dong, Sa; Bo, Zongyi; Zhang, Cunzheng; Feng, Jianguo; Liu, Xianjin

    2018-04-01

    Single-chain variable fragment (scFv) is a kind of antibody that possess only one chain of the complete antibody while maintaining the antigen-specific binding abilities and can be expressed in prokaryotic system. In this study, scFvs against Cry1 toxins were screened out from an immunized mouse phage displayed antibody library, which was successfully constructed with capacity of 6.25 × 10 7  CFU/mL. Using the mixed and alternative antigen coating strategy and after four rounds of affinity screening, seven positive phage-scFvs against Cry1 toxins were selected and characterized. Among them, clone scFv-3H9 (MG214869) showing relative stable and high binding abilities to six Cry1 toxins was selected for expression and purification. SDS-PAGE indicated that the scFv-3H9 fragments approximately 27 kDa were successfully expressed in Escherichia coli HB2151 strain. The purified scFv-3H9 was used to establish the double antibody sandwich enzyme-linked immunosorbent assay method (DAS-ELISA) for detecting six Cry1 toxins, of which the lowest detectable limits (LOD) and the lowest quantitative limits (LOQ) were 3.14-11.07 and 8.22-39.44 ng mL -1 , respectively, with the correlation coefficient higher than 0.997. The average recoveries of Cry1 toxins from spiked rice leaf samples were ranged from 84 to 95%, with coefficient of variation (CV) less than 8.2%, showing good accuracy for the multi-residue determination of six Cry1 toxins in agricultural samples. This research suggested that the constructed phage display antibody library based on the animal which was immunized with the mixture of several antigens under the same category can be used for the quick and effective screening of generic antibodies.

  5. Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse

    Directory of Open Access Journals (Sweden)

    Vandewauw Ine

    2013-02-01

    Full Text Available Abstract Background Somatosensory nerve fibres arising from cell bodies within the trigeminal ganglia (TG in the head and from a string of dorsal root ganglia (DRG located lateral to the spinal cord convey endogenous and environmental stimuli to the central nervous system. Although several members of the transient receptor potential (TRP superfamily of cation channels have been implicated in somatosensation, the expression levels of TRP channel genes in the individual sensory ganglia have never been systematically studied. Results Here, we used quantitative real-time PCR to analyse and compare mRNA expression of all TRP channels in TG and individual DRGs from 27 anatomically defined segments of the spinal cord of the mouse. At the mRNA level, 17 of the 28 TRP channel genes, TRPA1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPM3, TRPM4, TRPM5, TRPM6, TRPM7, TRPM8, TRPV1, TRPV2, TRPV4, TRPML1 and TRPP2, were detectable in every tested ganglion. Notably, four TRP channels, TRPC4, TRPM4, TRPM8 and TRPV1, showed statistically significant variation in mRNA levels between DRGs from different segments, suggesting ganglion-specific regulation of TRP channel gene expression. These ganglion-to-ganglion differences in TRP channel transcript levels may contribute to the variability in sensory responses in functional studies. Conclusions We developed, compared and refined techniques to quantitatively analyse the relative mRNA expression of all TRP channel genes at the single ganglion level. This study also provides for the first time a comparative mRNA distribution profile in TG and DRG along the entire vertebral column for the mammalian TRP channel family.

  6. Optimization of helical acquisition parameters to preserve uniformity of mouse whole body using multipinhole collimator in single-photon emission computed tomography

    Directory of Open Access Journals (Sweden)

    Naoyuki Ukon

    Full Text Available Focusing on whole-body uniformity in small-animal single-photon emission computed tomography (SPECT, we examined the optimal helical acquisition parameters using five-pinhole collimators for mouse imaging. SPECT images of an 80-mm-long cylindrical phantom with 99mTc solution were acquired using an Inveon multimodality imaging platform. The bed travels used in this study were 0, 30, 60, 90 and 120 mm, and the numbers of revolutions traversed during the SPECT scan were 1.0, 2.0, 3.0, 4.0, 5.0 and 7.0, respectively. Artifacts that degrade uniformity in reconstructed images were conspicuous when the bed travel was smaller than the object length. Regarding the distal-to-center ratio (DCR of SPECT values in the object’s axial direction, the DCR nearest to the ideal ratio of 1.00 was 1.02 in the optimal uniformity with 4.0 revolutions and a bed travel of 120 mm. Moreover, the helical acquisition using these parameters suppressed the formation of artifacts. We proposed the optimal parameters in whole-body helical SPECT; the bed travel was sufficiently larger than the object length; the 4.0 or more revolutions were required for a pitch of approximately 30 mm/revolution. The optimal acquisition parameters in SPECT to preserve uniformity would contribute to the accurate quantification of whole-body biodistribution. Keywords: Helical acquisition, Multipinhole collimator, Computed tomography, SPECT

  7. Reynolds number dependence of drag reduction by rodlike polymers

    NARCIS (Netherlands)

    Amarouchene, Y.; Bonn, D.; Kellay, H.; Lo, T.-S.; L'vov, V.S.; Procaccia, I.

    2008-01-01

    We present experimental and theoretical results addressing the Reynolds number (Re) dependence of drag reduction by sufficiently large concentrations of rodlike polymers in turbulent wall-bounded flows. It is shown that when Re is small the drag is enhanced. On the other hand, when Re increases, the

  8. Determination of the Drag Resistance Coefficients of Different Vehicles

    Science.gov (United States)

    Fahsl, Christoph; Vogt, Patrik

    2018-01-01

    While it has been demonstrated how air resistance could be analyzed by using mobile devices, this paper demonstrates a method of how to determine the drag resistance coefficient "c" of a commercial automobile by using the acceleration sensor of a smartphone or tablet. In an academic context, the drag resistance is often mentioned, but…

  9. Drag reduction through self-texturing compliant bionic materials

    Science.gov (United States)

    Liu, Eryong; Li, Longyang; Wang, Gang; Zeng, Zhixiang; Zhao, Wenjie; Xue, Qunji

    2017-01-01

    Compliant fish skin is effectively in reducing drag, thus the design and application of compliant bionic materials may be a good choice for drag reduction. Here we consider the drag reduction of compliant bionic materials. First, ZnO and PDMS mesh modified with n-octadecane were prepared, the drag reduction of self-texturing compliant n-octadecane were studied. The results show that the mesh modified by ZnO and PDMS possess excellent lipophilic and hydrophobic, thus n-octadecane at solid, semisolid and liquid state all have good adhesion with modified mesh. The states of n-octadecane changed with temperature, thus, the surface contact angle and adhesive force all varies obviously at different state. The contact angle decreases with temperature, the adhesive force shows a lower value at semisolid state. Furthermore, the drag testing results show that the compliant n-octadecane film is more effectively in drag reduction than superhydrophobic ZnO/PDMS film, indicating that the drag reduction mechanism of n-octadecane is significantly different with superhydrophobic film. Further research shows that the water flow leads to self-texturing of semisolid state n-octadecane, which is similar with compliant fish skin. Therefore, the compliant bionic materials of semisolid state n-octadecane with regular bulge plays a major role in the drag reduction.

  10. EFFECTIVENESS OF NYLON DRAG STRAPS FOR BRAKING MONORAIL SLEDS.

    Science.gov (United States)

    Velocity versus coast distance measurements on two monorail rocket sleds were conducted on the Holloman track to obtain numerical information on the...sleds and the drag straps. The straps as described are shown to increase the effective drag area of the monorail sleds used by approximately one square

  11. Spin-transfer mechanism for magnon-drag thermopower

    NARCIS (Netherlands)

    Lucassen, M.E.|info:eu-repo/dai/nl/314406913; Wong, C.H.; Duine, R.A.|info:eu-repo/dai/nl/304830127; Tserkovnyak, Y.

    2011-01-01

    We point out a relation between the dissipative spin-transfer-torque parameter β and the contribution of magnon drag to the thermoelectric power in conducting ferromagnets. Using this result, we estimate β in iron at low temperatures, where magnon drag is believed to be the dominant contribution to

  12. Analysis of Drag Reduction Methods and Mechanisms of Turbulent

    Directory of Open Access Journals (Sweden)

    Gu Yunqing

    2017-01-01

    Full Text Available Turbulent flow is a difficult issue in fluid dynamics, the rules of which have not been totally revealed up to now. Fluid in turbulent state will result in a greater frictional force, which must consume great energy. Therefore, it is not only an important influence in saving energy and improving energy utilization rate but also an extensive application prospect in many fields, such as ship domain and aerospace. Firstly, bionic drag reduction technology is reviewed and is a hot research issue now, the drag reduction mechanism of body surface structure is analyzed, such as sharks, earthworms, and dolphins. Besides, we make a thorough study of drag reduction characteristics and mechanisms of microgrooved surface and compliant wall. Then, the relevant drag reduction technologies and mechanisms are discussed, focusing on the microbubbles, the vibrant flexible wall, the coating, the polymer drag reduction additives, superhydrophobic surface, jet surface, traveling wave surface drag reduction, and the composite drag reduction methods. Finally, applications and advancements of the drag reduction technology in turbulence are prospected.

  13. Frictional drag between quantum wells mediated by phonon exchange

    DEFF Research Database (Denmark)

    Bønsager, M.C.; Flensberg, Karsten; Hu, Ben Yu-Kuang

    1998-01-01

    We use the Kubo formalism to evaluate the contribution of acoustic-phonon exchange to the frictional drag between nearby two-dimensional electron systems. In the case of free phonons, we find a divergent drag rate (tau(D)(-l)). However, tau(D)(-l) becomes finite when phonon scattering from either...

  14. Dancing droplets: Contact angle, drag, and confinement

    Science.gov (United States)

    Benusiglio, Adrien; Cira, Nate; Prakash, Manu

    2015-11-01

    When deposited on a clean glass slide, a mixture of water and propylene glycol forms a droplet of given contact angle, when both pure liquids spread. (Cira, Benusiglio, Prakash: Nature, 2015). The droplet is stabilized by a gradient of surface tension due to evaporation that induces a Marangoni flow from the border to the apex of the droplets. The apparent contact angle of the droplets depends on both their composition and the external humidity as captured by simple models. These droplets present remarkable properties such as lack of a large pinning force. We discuss the drag on these droplets as a function of various parameters. We show theoretical and experimental results of how various confinement geometries change the vapor gradient and the dynamics of droplet attraction.

  15. Analytical Ballistic Trajectories with Approximately Linear Drag

    Directory of Open Access Journals (Sweden)

    Giliam J. P. de Carpentier

    2014-01-01

    Full Text Available This paper introduces a practical analytical approximation of projectile trajectories in 2D and 3D roughly based on a linear drag model and explores a variety of different planning algorithms for these trajectories. Although the trajectories are only approximate, they still capture many of the characteristics of a real projectile in free fall under the influence of an invariant wind, gravitational pull, and terminal velocity, while the required math for these trajectories and planners is still simple enough to efficiently run on almost all modern hardware devices. Together, these properties make the proposed approach particularly useful for real-time applications where accuracy and performance need to be carefully balanced, such as in computer games.

  16. Future Drag Measurements from Venus Express

    Science.gov (United States)

    Keating, Gerald; Mueller-Wodarg, Ingo; Forbes, Jeffrey M.; Yelle, Roger; Bruinsma, Sean; Withers, Paul; Lopez-Valverde, Miguel Angel; Theriot, Res. Assoc. Michael; Bougher, Stephen

    Beginning in July 2008 during the Venus Express Extended Mission, the European Space Agency will dramatically drop orbital periapsis from near 250km to near 180km above the Venus North Polar Region. This will allow orbital decay measurements of atmospheric densities to be made near the Venus North Pole by the VExADE (Venus Express Atmospheric Drag Experiment) whose team leader is Ingo Mueller-Wodarg. VExADE consists of two parts VExADE-ODA (Orbital Drag Analysis from radio tracking data) and VExADE-ACC (Accelerometer in situ atmospheric density measurements). Previous orbital decay measurements of the Venus thermosphere were obtained by Pioneer Venus from the 1970's into the 1990's and from Magellan in the 1990's. The major difference is that the Venus Express will provide measurements in the North Polar Region on the day and night sides, while the earlier measurements were obtained primarily near the equator. The periapsis will drift upwards in altitude similar to the earlier spacecraft and then be commanded down to its lower original values. This cycle in altitude will allow estimates of vertical structure and thus thermospheric temperatures in addition to atmospheric densities. The periapsis may eventually be lowered even further so that accelerometers can more accurately obtain density measurements of the polar atmosphere as a function of altitude, latitude, longitude, local solar time, pressure, Ls, solar activity, and solar wind on each pass. Bias in accelerometer measurements will be determined and corrected for by accelerometer measurements obtained above the discernable atmosphere on each pass. The second experiment, VExADE-ACC, is similar to the accelerometer experiments aboard Mars Global Surveyor, Mars Odyssey, and Mars Reconnaissance Orbiter that carried similar accelerometers in orbit around Mars. The risk involved in the orbital decay and accelerometer measurements is minimal. We have not lost any spacecraft orbiting Venus or Mars due to unexpected

  17. MINOR HUMAN-ANTIBODY RESPONSE TO A MOUSE AND CHIMERIC MONOCLONAL-ANTIBODY AFTER A SINGLE IV INFUSION IN OVARIAN-CARCINOMA PATIENTS - A COMPARISON OF 5 ASSAYS

    NARCIS (Netherlands)

    BUIST, MR; KENEMANS, P; VANKAMP, GJ; Haisma, Hidde

    The human anti-(mouse Ig) antibody (HAMA) response was measured in serum of 52 patients suspected of having ovarian carcinoma who had received an i.v. injection of either the murine monoclonal antibody (mAb) OV-TL 3 F(ab')(2) (n = 28, 1 mg) or the chimeric mouse/human mAb MOv18 (cMOv18; n = 24, 3

  18. Minor human antibody response to a mouse and chimeric monoclonal antibody after a single i.v. infusion in ovarian carcinoma patients: a comparison of five assays

    NARCIS (Netherlands)

    Buist, M. R.; Kenemans, P.; van Kamp, G. J.; Haisma, H. J.

    1995-01-01

    The human anti-(mouse Ig) antibody (HAMA) response was measured in serum of 52 patients suspected of having ovarian carcinoma who had received an i.v. injection of either the murine monoclonal antibody (mAb) OV-TL 3 F(ab')2 (n = 28, 1 mg) or the chimeric mouse/human mAb MOv18 (cMOv18; n = 24, 3 mg).

  19. Friction and drag forces on spheres propagating down inclined planes

    Science.gov (United States)

    Tee, Yi Hui; Longmire, Ellen

    2017-11-01

    When a submerged sphere propagates along an inclined wall at terminal velocity, it experiences gravity, drag, lift, and friction forces. In the related equations of motion, the drag, lift and friction coefficients are unknown. Experiments are conducted to determine the friction and drag coefficients of the sphere over a range of Reynolds numbers. Through high speed imaging, translational and rotational velocities of spheres propagating along a glass plate are determined in liquids with several viscosities. The onset of sliding motion is identified by computing the dimensionless rotation rate of the sphere. Using drag and lift coefficients for Re friction coefficients are calculated for several materials. The friction coefficients are then employed to estimate the drag coefficient for 350 frictional force over this Re range. Supported by NSF (CBET-1510154).

  20. Airflow in Gravity Sewers - Determination of Wastewater Drag Coefficient.

    Science.gov (United States)

    Bentzen, Thomas Ruby; Østertoft, Kristian Kilsgaard; Vollertsen, Jes; Fuglsang, Emil Dietz; Nielsen, Asbjørn Haaning

    2016-03-01

    Several experiments have been conducted in order to improve the understanding of the wastewater drag and the wall frictional force acting on the headspace air in gravity sewers. The aim of the study is to improve the data basis for a numerical model of natural sewer ventilation. The results of the study shows that by integrating the top/side wall shear stresses the log-law models for the air velocity distribution along the unwetted perimeter resulted in a good agreement with the friction forces calculated by use of the Colebrook-White formula for hydraulic smooth pipes. Secondly, the water surface drags were found by log-law models of the velocity distribution in turbulent flows to fit velocity profiles measured from the water surface and by integrating the water surface drags along the wetted perimeter, mean water surface drags were found and a measure of the water surface drag coefficient was found.

  1. Electron drag in ferromagnetic structures separated by an insulating interface

    Science.gov (United States)

    Kozub, V. I.; Muradov, M. I.; Galperin, Y. M.

    2018-06-01

    We consider electron drag in a system of two ferromagnetic layers separated by an insulating interface. The source of it is expected to be magnon-electron interactions. Namely, we assume that the external voltage is applied to the "active" layer stimulating electric current through this layer. In its turn, the scattering of the current-carrying electrons by magnons leads to a magnon drag current within this layer. The 3-magnons interactions between magnons in the two layers (being of non-local nature) lead to magnon drag within the "passive" layer which, correspondingly, produce electron drag current via processes of magnon-electron scattering. We estimate the drag current and compare it to the phonon-induced one.

  2. Experimental evaluation of the drag force and drag torque acting on a rotating spherical particle moving in fluid

    Czech Academy of Sciences Publication Activity Database

    Lukerchenko, Nikolay; Kvurt, Y.; Kharlamov, Alexander; Chára, Zdeněk; Vlasák, Pavel

    2008-01-01

    Roč. 56, č. 2 (2008), s. 88-94 ISSN 0042-790X R&D Projects: GA AV ČR IAA200600603 Institutional research plan: CEZ:AV0Z20600510 Keywords : drag force * drag torque * spherical particle * rotational movement * translational movement Subject RIV: DA - Hydrology ; Limnology

  3. Bubble-induced skin-friction drag reduction and the abrupt transition to air-layer drag reduction

    Science.gov (United States)

    Elbing, Brian R.; Winkel, Eric S.; Lay, Keary A.; Ceccio, Steven L.; Dowling, David R.; Perlin, Marc

    To investigate the phenomena of skin-friction drag reduction in a turbulent boundary layer (TBL) at large scales and high Reynolds numbers, a set of experiments has been conducted at the US Navy's William B. Morgan Large Cavitation Channel (LCC). Drag reduction was achieved by injecting gas (air) from a line source through the wall of a nearly zero-pressure-gradient TBL that formed on a flat-plate test model that was either hydraulically smooth or fully rough. Two distinct drag-reduction phenomena were investigated; bubble drag reduction (BDR) and air-layer drag reduction (ALDR).The streamwise distribution of skin-friction drag reduction was monitored with six skin-friction balances at downstream-distance-based Reynolds numbers to 220 million and at test speeds to 20.0msinitial zone1. These results indicated that there are three distinct regions associated with drag reduction with air injection: Region I, BDR; Region II, transition between BDR and ALDR; and Region III, ALDR. In addition, once ALDR was established: friction drag reduction in excess of 80% was observed over the entire smooth model for speeds to 15.3ms1 with the surface fully roughened (though approximately 50% greater volumetric air flux was required); and ALDR was sensitive to the inflow conditions. The sensitivity to the inflow conditions can be mitigated by employing a small faired step (10mm height in the experiment) that helps to create a fixed separation line.

  4. Anomalous low-temperature Coulomb drag in graphene-GaAs heterostructures.

    Science.gov (United States)

    Gamucci, A; Spirito, D; Carrega, M; Karmakar, B; Lombardo, A; Bruna, M; Pfeiffer, L N; West, K W; Ferrari, A C; Polini, M; Pellegrini, V

    2014-12-19

    Vertical heterostructures combining different layered materials offer novel opportunities for applications and fundamental studies. Here we report a new class of heterostructures comprising a single-layer (or bilayer) graphene in close proximity to a quantum well created in GaAs and supporting a high-mobility two-dimensional electron gas. In our devices, graphene is naturally hole-doped, thereby allowing for the investigation of electron-hole interactions. We focus on the Coulomb drag transport measurements, which are sensitive to many-body effects, and find that the Coulomb drag resistivity significantly increases for temperatures law, therefore displaying a notable departure from the ordinary quadratic temperature dependence expected in a weakly correlated Fermi-liquid. This anomalous behaviour is consistent with the onset of strong interlayer correlations. Our heterostructures represent a new platform for the creation of coherent circuits and topologically protected quantum bits.

  5. Drag of ballistic electrons by an ion beam

    Energy Technology Data Exchange (ETDEWEB)

    Gurevich, V. L.; Muradov, M. I., E-mail: mag.muradov@mail.ioffe.ru [Russian Academy of Sciences, Ioffe Physicotechnical Institute (Russian Federation)

    2015-12-15

    Drag of electrons of a one-dimensional ballistic nanowire by a nearby one-dimensional beam of ions is considered. We assume that the ion beam is represented by an ensemble of heavy ions of the same velocity V. The ratio of the drag current to the primary current carried by the ion beam is calculated. The drag current turns out to be a nonmonotonic function of velocity V. It has a sharp maximum for V near v{sub nF}/2, where n is the number of the uppermost electron miniband (channel) taking part in conduction and v{sub nF} is the corresponding Fermi velocity. This means that the phenomenon of ion beam drag can be used for investigation of the electron spectra of ballistic nanostructures. We note that whereas observation of the Coulomb drag between two parallel quantum wires may in general be complicated by phenomena such as tunneling and phonon drag, the Coulomb drag of electrons of a one-dimensional ballistic nanowire by an ion beam is free of such spurious effects.

  6. Search for a solute-drag effect in dendritic solidification

    International Nuclear Information System (INIS)

    Eckler, K.; Herlach, D.M.; Aziz, M.J.

    1994-01-01

    The authors report the results of an indirect experimental test for the solute-drag effect in alloy solidification by fitting the data of Eckler et.al. for Ni-B dendrite tip velocities vs undercooling to models in several ways. The unknown equilibrium partition coefficient, k e , was varied as a fitting parameter. When they combine the dendrite growth model of Boettinger et al. with the Continuous Growth Model (CGM) of Aziz and Kaplan with solute drag, they cannot fit the data for any value of k e . When they combine dendrite growth theory with the CGM without solute drag, they obtain a reasonable fit to the data for k e = 4 x 10 -6 . When they combine dendrite growth theory with a new partial-solute-drag interpolation between the with-solute-drag and the without-solute-drag versions of the CGM, they obtain a still better fit to the data for k e = 2.8 x 10 - 4. This result points out the possibility of partial solute-drag during solidification and the importance of an independent determination of k e in order to distinguish between models

  7. Resolvent-based feedback control for turbulent friction drag reduction

    Science.gov (United States)

    Kawagoe, Aika; Nakashima, Satoshi; Luhar, Mitul; Fukagata, Koji

    2017-11-01

    Suboptimal control for turbulent friction drag reduction has been studied extensively. Nakashima et al. (accepted) extended resolvent analysis to suboptimal control, and for the control where the streamwise wall shear stress is used as an input (Case ST), they revealed the control effect across spectral space is mixed: there are regions of drag increase as well as reduction. This suggests that control performance may be improved if the control is applied for selective wavelengths, or if a new law is designed to suppress the spectral region leading to drag increase. In the present study, we first assess the effect of suboptimal control for selective wavelengths via DNS. The friction Reynolds number is set at 180. For Case ST, resolvent analysis predicts drag reduction at long streamwise wavelengths. DNS with control applied only for this spectral region, however, did not result in drag reduction. Then, we seek an effective control law using resolvent analysis and propose a new law. DNS results for this law are consistent with predictions from resolvent analysis, and about 10% drag reduction is attained. Further, we discuss how this law reduces the drag from a dynamical and theoretical point of view. This work was supported through Grant-in-Aid for Scientic Research (C) (No. 25420129) by Japan Society for the Promotion of Science (JSPS).

  8. Bilateral macular colobomata: Temporal dragging of optic disc

    Directory of Open Access Journals (Sweden)

    David J Mathew

    2015-01-01

    Full Text Available A 13-year-old male presented with decreased vision and squint from childhood. He had bilateral large colobomata at the macula in each eye, the one on the right being larger than the left. The disc was dragged temporally with straightening of the temporal retinal vessels. This is a case report of bilateral large macular coloboma and serves to report its association with a temporally dragged disc and straightened temporal retinal vessels. A dragged disc if present with a colobomatous defect at the macula may strengthen the case for diagnosis of macular coloboma and help exclude other differentials.

  9. Oscillating Sign of Drag in High Landau Levels

    International Nuclear Information System (INIS)

    von Oppen, Felix; Simon, Steven H.; Stern, Ady

    2001-01-01

    Motivated by experiments, we study the sign of the Coulomb drag voltage in a double layer system in a strong magnetic field. We show that the commonly used Fermi golden rule approach implicitly assumes a linear dependence of intralayer conductivity on density, and is thus inadequate in strong magnetic fields. Going beyond this approach, we show that the drag voltage commonly changes sign with density difference between the layers. We find that, in the quantum Hall regime, the Hall and longitudinal drag resistivities may be comparable. Our results are also relevant for pumping and acoustoelectric experiments

  10. Effect of guideway discontinuities on magnetic levitation and drag forces

    International Nuclear Information System (INIS)

    Rossing, T.D.; Korte, R.; Hull, J.R.

    1991-01-01

    Transients in the lift and drag forces on a NdFeB permanent magnet were observed as the magnet passed over various discontinuities in a rotating aluminum disk at velocities of 4 to 25 m/s. For full cuts in the disk, the amplitude of the lift and drag transients and the wave form of the drag transient depend on the width, and the amplitudes are much larger than for partial cuts. The use of a backing plate to join two cut segments is ineffective

  11. Investigation of Drag Coefficient for Rigid Ballute-like Shapes

    Science.gov (United States)

    Carnasciali, Maria-Isabel; Mastromarino, Anthony

    2014-11-01

    One common method of decelerating an object during atmospheric entry, descent, and landing is the use of parachutes. Another deceleration technology is the ballute - a combination of balloon and parachute. A CFD study was conducted using commercially available software to investigate the flow-field and the coefficient of drag for various rigid ballute-like shapes at varying Reynolds numbers. The impact of size and placement of the burble-fence as well as number, size, and shape of inlets was considered. Recent experimental measurements conducted during NASA's Low-Density Supersonic Decelerator program revealed a much higher coefficient of drag (Cd) for ballutes than previously encountered. Using atmospheric drag to slow down and land reduces the need for heavy fuel and rocket engines and thus, high values of drag are desired. Funding for this work, in part, provided by the CT Space Grant Consortium.

  12. Drag Reduction through Pulsed Plasma Actuators, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Drag reduction is a fundamental necessity in all aerodynamic designs, as it directly affects aircraft fuel efficiency which in turn affects endurance, range, and...

  13. Influence of Surface Roughness on Polymer Drag Reduction

    National Research Council Canada - National Science Library

    Ceccio, Steven L; Dowling, David R; Perlin, Marc; Solomon, Michael

    2007-01-01

    .... The details of that effort can be found in the final technical report for that project. The purpose of the additional investigation was to examine the physics and engineering of friction drag reduction methods for turbulent boundary layers (TBL...

  14. Drag force and jet propulsion investigation of a swimming squid

    Directory of Open Access Journals (Sweden)

    Tabatabaei Mahdi

    2015-01-01

    Full Text Available In this study, CAD model of a squid was obtained by taking computer tomography images of a real squid. The model later placed into a computational domain to calculate drag force and performance of jet propulsion. The drag study was performed on the CAD model so that drag force subjected to real squid was revealed at squid’s different swimming speeds and comparison has been made with other underwater creatures (e.g., a dolphin, sea lion and penguin. The drag coefficient (referenced to total wetted surface area of squid is 0.0042 at Reynolds number 1.6x106 that is a %4.5 difference from Gentoo penguin. Besides, jet flow of squid was simulated to observe the flow region generated in the 2D domain utilizing dynamic mesh method to mimic the movement of squid’s mantle cavity.

  15. Experimental study of drag reduction in flumes and spillway tunnels

    Directory of Open Access Journals (Sweden)

    Ying-kui Wang

    2010-06-01

    Full Text Available Experiments in an open flume model and spillway tunnel model were carried out using drag reduction techniques. Two drag reduction techniques were adopted in the experiments: polymer addition and coating. The drag reduction effect of a polyacrylamide (PAM solution and dimethyl silicone oil coating were studied in the flume model experiments, and the results were analyzed. Experiments were then carried out with a model of the Xiluodu Hydropower Station, the second largest dam in China. In order to reduce the resistance, the spillway tunnels were internally coated with dimethyl silicone oil. This is the first time that these drag reduction techniques have been applied to so large a hydraulic model. The experimental results show that the coating technique can effectively increase flood discharge. The outlet velocity and the jet trajectory distance are also increased, which enhances the energy dissipation of the spillway tunnel.

  16. Wall temperature control of low-speed body drag

    Science.gov (United States)

    Lin, J. C.; Ash, R. L.

    1986-01-01

    The use of thermal means to control drag under turbulent boundary layer conditions is examined. Numerical calculations are presented for both skin friction and (unseparated) pressure drag for turbulent boundary-layer flows over a fuselage-like body with wall heat transfer. In addition, thermal control of separation on a bluff body is investigated. It is shown that a total drag reduction of up to 20 percent can be achieved for wall heating with a wall-to-total-freestream temperature ratio of 2. For streamlined slender bodies, partial wall heating of the forebody can produce almost the same order of total drag reduction as the full body heating case. For bluff bodies, the separation delay from partial wall cooling of the afterbody is approximately the same as for the fully cooled body.

  17. Atomistically informed solute drag in Al–Mg

    International Nuclear Information System (INIS)

    Zhang, F; Curtin, W A

    2008-01-01

    Solute drag in solute-strengthened alloys, caused by diffusion of solute atoms around moving dislocations, controls the stress at deformation rates and temperatures useful for plastic forming processes. In the technologically important Al–Mg alloys, the solute drag stresses predicted by classical theories are much larger than experiments, which is resolved in general by eliminating the singularity of the dislocation core via Peierls–Nabarro-type models. Here, the drag stress versus dislocation velocity is computed numerically using a realistic dislocation core structure obtained from an atomistic model to investigate the role of the core and obtain quantitative stresses for comparison with experiment. The model solves a discrete diffusion equation in a reference frame moving with the dislocation, with input solute enthalpies and diffusion activation barriers in the core computed by or estimated from atomistic studies. At low dislocation velocities, the solute drag stress is controlled by bulk solute diffusion because the core diffusion occurs too quickly. In this regime, the drag stress can be obtained using a Peierls–Nabarro model with a core spreading parameter tuned to best match the atomistic models. At intermediate velocities, both bulk and core diffusion can contribute to the drag, leading to a complex stress–velocity relationship showing two peaks in stress. At high velocities, the drag stress is controlled solely by diffusion within and across the core. Like the continuum models, the drag stress is nearly linear in solute concentration. The Orowan relationship is used to connect dislocation velocity to deformation strain rate. Accounting for the dependence of mobile dislocation density on stress, the simulations are in good agreement with experiments on Al–Mg alloys over a range of concentrations and temperatures

  18. Drag force in a D-instanton background

    Science.gov (United States)

    Zhang, Zi-qiang; Luo, Zhong-jie; Hou, De-fu

    2018-06-01

    We study the drag force and diffusion coefficient with respect to a moving heavy quark in a D-instanton background, which corresponds to the Yang-Mills theory in the deconfining, high-temperature phase. It is shown that the presence of the D-instanton density tends to increase the drag force and decrease the diffusion coefficient, reverse to the effects of the velocity and the temperature. Moreover, the inclusion of the D-instanton density makes the medium less viscous.

  19. Thermal Transport and Drag Force in Improved Holographic QCD

    CERN Document Server

    Gürsoy, Umut; Michalogiorgakis, Georgios; Nitti, Francesco; 10.1088

    2009-01-01

    We calculate the bulk viscosity, drag force and jet quenching parameter in Improved Holographic QCD. We find that the bulk viscosity rises near the phase transition but does not exceed the shear viscosity. The drag force shows the effects of asymptotic freedom both as a function of velocity and temperature. It indicates diffusion times of heavy quarks in rough agreement with data. The jet quenching parameter values computed via the light-like Wilson loop are in the lower range suggested by data.

  20. Progress towards a Drag-free SmallSat

    Science.gov (United States)

    Saraf, Shailendhar

    The net force acting on a drag-free satellite is purely gravitational as all other forces, mainly atmospheric drag and solar radiation pressure, are canceled out. In order to achieve this, a free floating reference (test mass) inside the satellite is shielded against all forces but gravity and a system of thrusters is commanded by a control algorithm such that the relative displacement between the reference and the satellite stays constant. The main input to that control algorithm is the output of a sensor which measures the relative displacement between the satellite and the test mass. Internal disturbance forces such as electrostatic or magnetic forces cannot be canceled out his way and have to be minimized by a careful design of the satellite. A drag-free technology package is under development at Stanford since 2004. It includes an optical displacement sensor to measure the relative position of the test mass inside the satellite, a caging mechanism to lock the test mass during launch, a UV LED based charge management system to minimize the effect of electrostatic forces, a thermal enclosure, and the drag-free control algorithms. Possible applications of drag-free satellites in fundamental physics (Gravity Probe B, LISA), geodesy (GOCE), and navigation (TRIAD I). In this presentation we will highlight the progress of the technology development towards a drag-free mission. The planned mission on a SaudiSat bus will demonstrate drag-free technology on a small spacecraft at a fraction of the cost of previous drag-free missions. The target acceleration noise is 10-12 m/sec2. With multiple such satellites a GRACE-like mission with improved sensitivity and potentially improved spatial and temporal resolution can be achieved.

  1. Mouse adhalin

    DEFF Research Database (Denmark)

    Liu, L; Vachon, P H; Kuang, W

    1997-01-01

    . To analyze the biological roles of adhalin, we cloned the mouse adhalin cDNA, raised peptide-specific antibodies to its cytoplasmic domain, and examined its expression and localization in vivo and in vitro. The mouse adhalin sequence was 80% identical to that of human, rabbit, and hamster. Adhalin...... was specifically expressed in striated muscle cells and their immediate precursors, and absent in many other cell types. Adhalin expression in embryonic mouse muscle was coincident with primary myogenesis. Its expression was found to be up-regulated at mRNA and protein levels during myogenic differentiation...

  2. Linear drag law for high-Reynolds-number flow past an oscillating body

    Science.gov (United States)

    Agre, Natalie; Childress, Stephen; Zhang, Jun; Ristroph, Leif

    2016-07-01

    An object immersed in a fast flow typically experiences fluid forces that increase with the square of speed. Here we explore how this high-Reynolds-number force-speed relationship is affected by unsteady motions of a body. Experiments on disks that are driven to oscillate while progressing through air reveal two distinct regimes: a conventional quadratic relationship for slow oscillations and an anomalous scaling for fast flapping in which the time-averaged drag increases linearly with flow speed. In the linear regime, flow visualization shows that a pair of counterrotating vortices is shed with each oscillation and a model that views a train of such dipoles as a momentum jet reproduces the linearity. We also show that appropriate scaling variables collapse the experimental data from both regimes and for different oscillatory motions into a single drag-speed relationship. These results could provide insight into the aerodynamic resistance incurred by oscillating wings in flight and they suggest that vibrations can be an effective means to actively control the drag on an object.

  3. Air-Induced Drag Reduction at High Reynolds Numbers: Velocity and Void Fraction Profiles

    Science.gov (United States)

    Elbing, Brian; Mäkiharju, Simo; Wiggins, Andrew; Dowling, David; Perlin, Marc; Ceccio, Steven

    2010-11-01

    The injection of air into a turbulent boundary layer forming over a flat plate can reduce the skin friction. With sufficient volumetric fluxes an air layer can separate the solid surface from the flowing liquid, which can produce drag reduction in excess of 80%. Several large scale experiments have been conducted at the US Navy's Large Cavitation Channel on a 12.9 m long flat plate model investigating bubble drag reduction (BDR), air layer drag reduction (ALDR) and the transition between BDR and ALDR. The most recent experiment acquired phase velocities and void fraction profiles at three downstream locations (3.6, 5.9 and 10.6 m downstream from the model leading edge) for a single flow speed (˜6.4 m/s). The profiles were acquired with a combination of electrode point probes, time-of-flight sensors, Pitot tubes and an LDV system. Additional diagnostics included skin-friction sensors and flow-field image visualization. During this experiment the inlet flow was perturbed with vortex generators immediately upstream of the injection location to assess the robustness of the air layer. From these, and prior measurements, computational models can be refined to help assess the viability of ALDR for full-scale ship applications.

  4. Immunostimulatory mouse granuloma protein.

    Science.gov (United States)

    Fontan, E; Fauve, R M; Hevin, B; Jusforgues, H

    1983-10-01

    Earlier studies have shown that from subcutaneous talc-induced granuloma in mice, a fraction could be extracted that fully protected mice against Listeria monocytogenes. Using standard biochemical procedures--i.e., ammonium sulfate fractionation, preparative electrophoresis, gel filtration chromatography, isoelectric focusing, and preparative polyacrylamide gel electrophoresis--we have now purified an active factor to homogeneity. A single band was obtained in NaDodSO4/polyacrylamide gel with an apparent Mr of 55,000. It migrated with alpha 1-globulins and the isoelectric point was 5 +/- 0.1. The biological activity was destroyed with Pronase but not with trypsin and a monospecific polyclonal rabbit antiserum was obtained. The intravenous injection of 5 micrograms of this "mouse granuloma protein" fully protects mice against a lethal inoculum of L. monocytogenes. Moreover, after their incubation with 10 nM mouse granuloma protein, mouse peritoneal cells became cytostatic against Lewis carcinoma cells.

  5. Navier slip model of drag reduction by Leidenfrost vapor layers

    KAUST Repository

    Berry, Joseph D.; Vakarelski, Ivan Uriev; Chan, Derek Y. C.; Thoroddsen, Sigurdur T

    2017-01-01

    Recent experiments found that a hot solid sphere that is able to sustain a stable Leidenfrost vapor layer in a liquid exhibits significant drag reduction during free fall. The variation of the drag coefficient with Reynolds number deviates substantially from the characteristic drag crisis behavior at high Reynolds numbers. Measurements based on liquids of different viscosities show that the onset of the drag crisis depends on the viscosity ratio of the vapor to the liquid. Here we attempt to characterize the complexity of the Leidenfrost vapor layer with respect to its variable thickness and possible vapor circulation within, in terms of the Navier slip model that is defined by a slip length. Such a model can facilitate tangential flow and thereby alter the behavior of the boundary layer. Direct numerical and large eddy simulations of flow past a sphere at moderate to high Reynolds numbers (102≤Re≤4×104) are employed to quantify comparisons with experimental results, including the drag coefficient and the form of the downstream wake on the sphere. This provides a simple one parameter characterization of the drag reduction phenomenon due to a stable vapor layer that envelops a solid body.

  6. Navier slip model of drag reduction by Leidenfrost vapor layers

    KAUST Repository

    Berry, Joseph D.

    2017-10-17

    Recent experiments found that a hot solid sphere that is able to sustain a stable Leidenfrost vapor layer in a liquid exhibits significant drag reduction during free fall. The variation of the drag coefficient with Reynolds number deviates substantially from the characteristic drag crisis behavior at high Reynolds numbers. Measurements based on liquids of different viscosities show that the onset of the drag crisis depends on the viscosity ratio of the vapor to the liquid. Here we attempt to characterize the complexity of the Leidenfrost vapor layer with respect to its variable thickness and possible vapor circulation within, in terms of the Navier slip model that is defined by a slip length. Such a model can facilitate tangential flow and thereby alter the behavior of the boundary layer. Direct numerical and large eddy simulations of flow past a sphere at moderate to high Reynolds numbers (102≤Re≤4×104) are employed to quantify comparisons with experimental results, including the drag coefficient and the form of the downstream wake on the sphere. This provides a simple one parameter characterization of the drag reduction phenomenon due to a stable vapor layer that envelops a solid body.

  7. Dragging of inertial frames inside the rotating neutron stars

    Energy Technology Data Exchange (ETDEWEB)

    Chakraborty, Chandrachur; Modak, Kamakshya Prasad; Bandyopadhyay, Debades, E-mail: chandrachur.chakraborty@saha.ac.in, E-mail: kamakshya.modak@saha.ac.in [Astroparticle Physics and Cosmology Division, Saha Institute of Nuclear Physics, Kolkata 700064 (India)

    2014-07-20

    We derive the exact frame-dragging rate inside rotating neutron stars. This formula is applied to show that the frame-dragging rate monotonically decreases from the center to the surface of the neutron star along the pole. In the case of the frame-dragging rate along the equatorial distance, it decreases initially away from the center, becomes negligibly small well before the surface of the neutron star, rises again, and finally approaches to a small value at the surface. The appearance of a local maximum and minimum in this case is the result of the dependence of frame-dragging frequency on the distance and angle. Moving from the equator to the pole, it is observed that this local maximum and minimum in the frame-dragging rate along the equator disappear after crossing a critical angle. It is also noted that the positions of the local maximum and minimum of the frame-dragging rate along the equator depend on the rotation frequency and central energy density of a particular pulsar.

  8. Aerodynamic drag of modern soccer balls.

    Science.gov (United States)

    Asai, Takeshi; Seo, Kazuya

    2013-12-01

    Soccer balls such as the Adidas Roteiro that have been used in soccer tournaments thus far had 32 pentagonal and hexagonal panels. Recently, the Adidas Teamgeist II and Adidas Jabulani, respectively having 14 and 8 panels, have been used at tournaments; the aerodynamic characteristics of these balls have not yet been verified. Now, the Adidas Tango 12, having 32 panels, has been developed for use at tournaments; therefore, it is necessary to understand its aerodynamic characteristics. Through a wind tunnel test and ball trajectory simulations, this study shows that the aerodynamic resistance of the new 32-panel soccer ball is larger in the high-speed region and lower in the middle-speed region than that of the previous 14- and 8-panel balls. The critical Reynolds number of the Roteiro, Teamgeist II, Jabulani, and Tango 12 was ~2.2 × 10(5) (drag coefficient, C d  ≈ 0.12), ~2.8 × 10(5) (C d  ≈ 0.13), ~3.3 × 10(5) (C d  ≈ 0.13), and ~2.4 × 10(5) (C d  ≈ 0.15), respectively. The flight trajectory simulation suggested that the Tango 12, one of the newest soccer balls, has less air resistance in the medium-speed region than the Jabulani and can thus easily acquire large initial velocity in this region. It is considered that the critical Reynolds number of a soccer ball, as considered within the scope of this experiment, depends on the extended total distance of the panel bonds rather than the small designs on the panel surfaces.

  9. Flux-flow drag in coupled Josephson junctions

    International Nuclear Information System (INIS)

    Parmentier, R.D.; Barbara, P.; Costabile, G.; DAnna, A.; Malomed, B.A.; Soriano, C.

    1997-01-01

    We present a detailed analysis of the interaction between two fluxon chains in parallel magnetically coupled long Josephson junctions, one of which is biased (open-quotes generatorclose quotes) while another is unbiased (open-quotes detectorclose quotes). The main effect is that the driven fluxon chain in the generator may drag the chain in the detector. We note that five different regimes of the interaction are possible: both chains may be pinned by the external magnetic field; both may move in a locked state, inducing the same dc voltage in both junctions; in an unlocked state they may move at different velocities; the chain in the detector may remain pinned while the one in the generator is moving; and, finally, in a limited range of parameters the mean detector voltage may be negative, which implies that the detector chain is moving in the direction opposite to that of the chain in the generator. We consider a simplified model based on the assumptions that the fluxon chains are dense and rigid, and that their motion is nonrelativistic. In this model, each chain is represented by a single degree of freedom (its coordinate). Numerical and analytical consideration of the simplified model demonstrates that it is able to reproduce correctly all the dynamical regimes except for the negative-voltage one. To explain the existence of the latter regime, we introduce another model, suggested by the simulations, which is based on the presence of two fluxons and one antifluxon in the generator, and a single fluxon in the detector. The negative voltage is produced by motion of the antifluxon in a bound state with the detector close-quote s fluxon. The existence region of this state is limited by its collisions with free fluxons in the generator. copyright 1997 The American Physical Society

  10. A Numerical Method for Calculating the Wave Drag of a Configuration from the Second Derivative of the Area Distribution of a Series of Equivalent Bodies of Revolution

    Science.gov (United States)

    Levy, Lionel L., Jr.; Yoshikawa, Kenneth K.

    1959-01-01

    A method based on linearized and slender-body theories, which is easily adapted to electronic-machine computing equipment, is developed for calculating the zero-lift wave drag of single- and multiple-component configurations from a knowledge of the second derivative of the area distribution of a series of equivalent bodies of revolution. The accuracy and computational time required of the method to calculate zero-lift wave drag is evaluated relative to another numerical method which employs the Tchebichef form of harmonic analysis of the area distribution of a series of equivalent bodies of revolution. The results of the evaluation indicate that the total zero-lift wave drag of a multiple-component configuration can generally be calculated most accurately as the sum of the zero-lift wave drag of each component alone plus the zero-lift interference wave drag between all pairs of components. The accuracy and computational time required of both methods to calculate total zero-lift wave drag at supersonic Mach numbers is comparable for airplane-type configurations. For systems of bodies of revolution both methods yield similar results with comparable accuracy; however, the present method only requires up to 60 percent of the computing time required of the harmonic-analysis method for two bodies of revolution and less time for a larger number of bodies.

  11. Nation Drag: Uses of the Exotic

    Directory of Open Access Journals (Sweden)

    Micol Seigel

    2009-02-01

    Full Text Available

    In Uneven Encounters, the forthcoming book from which this article is excerpted, Micol Seigel chronicles the exchange of popular culture between Brazil and the United States in the years between the World Wars, and she demonstrates how that exchange affected ideas of race and nation in both countries. From Americans interpreting advertisements for Brazilian coffee or dancing the Brazilian maxixe, to Rio musicians embracing the “foreign” qualities of jazz, Seigel traces a lively, cultural back-and-forth. Along the way, she shows how race and nation are constructed together, by both non-elites and elites, and gleaned from global cultural and intellectual currents as well as local, regional, and national ones. Seigel explores the circulation of images of Brazilian coffee and of maxixe in the United States during the period just after the imperial expansions of the early twentieth century. Exoticist interpretations structured North Americans’ paradoxical sense of self as productive “consumer citizens.” Some people, however, could not simply assume the privileges of citizenship. In their struggles against racism, Afro-descended citizens living in the cities of Rio de Janeiro, São Paulo, New York, and Chicago encountered images and notions of each other, and found them useful. Seigel introduces readers to cosmopolitan Afro-Brazilians and African Americans who rarely traveled far but who absorbed ideas from abroad nonetheless. African American vaudeville artists saw the utility of pretending to “be” Brazilian to cross the color line on stage. Putting on “nation drag,” they passed not from one race to another but out of familiar racial categories entirely. Afro-Brazilian journalists reported intensively on foreign, particularly North American, news and eventually entered into conversation with the U.S. black press in a collaborative but still conflictual dialogue. Seigel suggests that projects comparing U.S. and

  12. Nation Drag: Uses of the Exotic

    Directory of Open Access Journals (Sweden)

    Micol Seigel

    2009-02-01

    Full Text Available In Uneven Encounters, the forthcoming book from which this article is excerpted, Micol Seigel chronicles the exchange of popular culture between Brazil and the United States in the years between the World Wars, and she demonstrates how that exchange affected ideas of race and nation in both countries. From Americans interpreting advertisements for Brazilian coffee or dancing the Brazilian maxixe, to Rio musicians embracing the “foreign” qualities of jazz, Seigel traces a lively, cultural back-and-forth. Along the way, she shows how race and nation are constructed together, by both non-elites and elites, and gleaned from global cultural and intellectual currents as well as local, regional, and national ones. Seigel explores the circulation of images of Brazilian coffee and of maxixe in the United States during the period just after the imperial expansions of the early twentieth century. Exoticist interpretations structured North Americans’ paradoxical sense of self as productive “consumer citizens.” Some people, however, could not simply assume the privileges of citizenship. In their struggles against racism, Afro-descended citizens living in the cities of Rio de Janeiro, São Paulo, New York, and Chicago encountered images and notions of each other, and found them useful. Seigel introduces readers to cosmopolitan Afro-Brazilians and African Americans who rarely traveled far but who absorbed ideas from abroad nonetheless. African American vaudeville artists saw the utility of pretending to “be” Brazilian to cross the color line on stage. Putting on “nation drag,” they passed not from one race to another but out of familiar racial categories entirely. Afro-Brazilian journalists reported intensively on foreign, particularly North American, news and eventually entered into conversation with the U.S. black press in a collaborative but still conflictual dialogue. Seigel suggests that projects comparing U.S. and Brazilian racial

  13. Wind-Tunnel Investigations of Blunt-Body Drag Reduction Using Forebody Surface Roughness

    Science.gov (United States)

    Whitmore, Stephen A.; Sprague, Stephanie; Naughton, Jonathan W.; Curry, Robert E. (Technical Monitor)

    2001-01-01

    This paper presents results of wind-tunnel tests that demonstrate a novel drag reduction technique for blunt-based vehicles. For these tests, the forebody roughness of a blunt-based model was modified using micomachined surface overlays. As forebody roughness increases, boundary layer at the model aft thickens and reduces the shearing effect of external flow on the separated flow behind the base region, resulting in reduced base drag. For vehicle configurations with large base drag, existing data predict that a small increment in forebody friction drag will result in a relatively large decrease in base drag. If the added increment in forebody skin drag is optimized with respect to base drag, reducing the total drag of the configuration is possible. The wind-tunnel tests results conclusively demonstrate the existence of a forebody dragbase drag optimal point. The data demonstrate that the base drag coefficient corresponding to the drag minimum lies between 0.225 and 0.275, referenced to the base area. Most importantly, the data show a drag reduction of approximately 15% when the drag optimum is reached. When this drag reduction is scaled to the X-33 base area, drag savings approaching 45,000 N (10,000 lbf) can be realized.

  14. The Effect of Volumetric Porosity on Roughness Element Drag

    Science.gov (United States)

    Gillies, John; Nickling, William; Nikolich, George; Etyemezian, Vicken

    2016-04-01

    Much attention has been given to understanding how the porosity of two dimensional structures affects the drag force exerted by boundary-layer flow on these flow obstructions. Porous structures such as wind breaks and fences are typically used to control the sedimentation of sand and snow particles or create micro-habitats in their lee. Vegetation in drylands also exerts control on sediment transport by wind due to aerodynamic effects and interaction with particles in transport. Recent research has also demonstrated that large spatial arrays of solid three dimensional roughness elements can be used to reduce sand transport to specified targets for control of wind erosion through the effect of drag partitioning and interaction of the moving sand with the large (>0.3 m high) roughness elements, but porous elements may improve the effectiveness of this approach. A thorough understanding of the role porosity plays in affecting the drag force on three-dimensional forms is lacking. To provide basic understanding of the relationship between the porosity of roughness elements and the force of drag exerted on them by fluid flow, we undertook a wind tunnel study that systematically altered the porosity of roughness elements of defined geometry (cubes, rectangular cylinders, and round cylinders) and measured the associated change in the drag force on the elements under similar Reynolds number conditions. The elements tested were of four basic forms: 1) same sized cubes with tubes of known diameter milled through them creating three volumetric porosity values and increasing connectivity between the tubes, 2) cubes and rectangular cylinders constructed of brass screen that nested within each other, and 3) round cylinders constructed of brass screen that nested within each other. The two-dimensional porosity, defined as the ratio of total surface area of the empty space to the solid surface area of the side of the element presented to the fluid flow was conserved at 0.519 for

  15. The Overall Drag Losses For A Combination of Bodies

    Directory of Open Access Journals (Sweden)

    Sabah Al-Janabi

    2013-05-01

    Full Text Available The objective of this work is to obtain better understanding of the flow over a combination of bluff bodies in close enough proximity to strongly interact with each other. This interaction is often beneficial in that the drag of the overall system is reduced. Proto-types for this problem come from tractor- trailer and missiles, and from various add-on devices designed to reduce their drag. Thus, an experimental investigation was carried out by placing  conical frontal bodies having a base diameter of 0.65 cylinder diameter with different vertex angles (30°, 50°, 70°, and 90°. It was found that, the bluffer cone with 90° vertex angle gives the best minimum drag, which is 31% lower than the drag of the isolated cylinder. Also an interesting phenomenon was observed in that, the minimum drags for all combinations are obtained at the same gap ratio (i.e.at g/d2= 0.365.

  16. A Conventional Liner Acoustic/Drag Interaction Benchmark Database

    Science.gov (United States)

    Howerton, Brian M.; Jones, Michael G.

    2017-01-01

    The aerodynamic drag of acoustic liners has become a significant topic in the design of such for aircraft noise applications. In order to evaluate the benefits of concepts designed to reduce liner drag, it is necessary to establish the baseline performance of liners employing the typical design features of conventional configurations. This paper details a set of experiments in the NASA Langley Grazing Flow Impedance Tube to quantify the relative drag of a number of perforate-over-honeycomb liner configurations at flow speeds of M=0.3 and 0.5. These conventional liners are investigated to determine their resistance factors using a static pressure drop approach. Comparison of the resistance factors gives a relative measurement of liner drag. For these same flow conditions, acoustic measurements are performed with tonal excitation from 400 to 3000 Hz at source sound pressure levels of 140 and 150 dB. Educed impedance and attenuation spectra are used to determine the interaction between acoustic performance and drag.

  17. Relativistic Gas Drag on Dust Grains and Implications

    Energy Technology Data Exchange (ETDEWEB)

    Hoang, Thiem, E-mail: thiemhoang@kasi.re.kr [Korea Astronomy and Space Science Institute, Daejeon 34055 (Korea, Republic of); Korea University of Science and Technology, Daejeon, 34113 (Korea, Republic of)

    2017-09-20

    We study the drag force on grains moving at relativistic velocities through interstellar gas and explore its application. First, we derive a new analytical formula of the drag force at high energies and find that it is significantly reduced compared to the classical model. Second, we apply the obtained drag force to calculate the terminal velocities of interstellar grains by strong radiation sources such as supernovae and active galactic nuclei (AGNs). We find that grains can be accelerated to relativistic velocities by very luminous AGNs. We then quantify the deceleration of relativistic spacecraft proposed by the Breakthrough Starshot initiative due to gas drag on a relativistic lightsail. We find that the spacecraft’s decrease in speed is negligible because of the suppression of gas drag at relativistic velocities, suggesting that the lightsail may be open for communication during its journey to α Centauri without causing a considerable delay. Finally, we show that the damage to relativistic thin lightsails by interstellar dust is a minor effect.

  18. Drag reduction in channel flow using nonlinear control

    Science.gov (United States)

    Keefe, Laurence R.

    1993-01-01

    Two nonlinear control schemes have been applied to the problem of drag reduction in channel flow. Both schemes have been tested using numerical simulations at a mass flux Reynolds numbers of 4408, utilizing 2D nonlinear neutral modes for goal dynamics. The OGY-method, which requires feedback, reduces drag to 60-80 percent of the turbulent value at the same Reynolds number, and employs forcing only within a thin region near the wall. The H-method, or model-based control, fails to achieve any drag reduction when starting from a fully turbulent initial condition, but shows potential for suppressing or retarding laminar-to-turbulent transition by imposing instead a transition to a low drag, nonlinear traveling wave solution to the Navier-Stokes equation. The drag in this state corresponds to that achieved by the OGY-method. Model-based control requires no feedback, but in experiments to date has required the forcing be imposed within a thicker layer than the OGY-method. Control energy expenditures in both methods are small, representing less than 0.1 percent of the uncontrolled flow's energy.

  19. Creating drag and lift curves from soccer trajectories

    Science.gov (United States)

    Goff, John Eric; Kelley, John; Hobson, Chad M.; Seo, Kazuya; Asai, Takeshi; Choppin, S. B.

    2017-07-01

    Trajectory analysis is an alternative to using wind tunnels to measure a soccer ball’s aerodynamic properties. It has advantages over wind tunnel testing such as being more representative of game play. However, previous work has not presented a method that produces complete, speed-dependent drag and lift coefficients. Four high-speed cameras in stereo-calibrated pairs were used to measure the spatial co-ordinates for 29 separate soccer trajectories. Those trajectories span a range of launch speeds from 9.3 to 29.9 m s-1. That range encompasses low-speed laminar flow of air over a soccer ball, through the drag crises where air flow is both laminar and turbulent, and up to high-speed turbulent air flow. Results from trajectory analysis were combined to give speed-dependent drag and lift coefficient curves for the entire range of speeds found in the 29 trajectories. The average root mean square error between the measured and modelled trajectory was 0.028 m horizontally and 0.034 m vertically. The drag and lift crises can be observed in the plots of drag and lift coefficients respectively.

  20. Theory of Coulomb drag for massless Dirac fermions

    International Nuclear Information System (INIS)

    Carrega, M; Principi, A; Polini, M; Tudorovskiy, T; Katsnelson, M I

    2012-01-01

    Coulomb drag between two unhybridized graphene sheets separated by a dielectric spacer has recently attracted considerable theoretical interest. We first review, for the sake of completeness, the main analytical results which have been obtained by other authors. We then illustrate pedagogically the minimal theory of Coulomb drag between two spatially separated two-dimensional systems of massless Dirac fermions which are both away from the charge-neutrality point. This relies on second-order perturbation theory in the screened interlayer interaction and on Boltzmann-transport theory. In this theoretical framework and in the low-temperature limit, we demonstrate that, to leading (i.e. quadratic) order in temperature, the drag transresistivity is completely insensitive to the precise intralayer momentum-relaxation mechanism (i.e. to the functional dependence of the transport scattering time on energy). We also provide analytical results for the low-temperature drag transresistivity for both cases of ‘thick’ and ‘thin’ spacers and for arbitrary values of the dielectric constants of the media surrounding the two Dirac-fermion layers. Finally, we present numerical results for the low-temperature drag transresistivity for the case when one of the media surrounding the Dirac-fermion layers has a frequency-dependent dielectric constant. We conclude by suggesting an experiment that can potentially allow for the observation of departures from the canonical quadratic-in-temperature behavior of the transresistivity. (paper)

  1. Chitinase mRNA levels by quantitative PCR using the single standard DNA: acidic mammalian chitinase is a major transcript in the mouse stomach.

    Directory of Open Access Journals (Sweden)

    Misa Ohno

    Full Text Available Chitinases hydrolyze the β-1-4 glycosidic bonds of chitin, a major structural component of fungi, crustaceans and insects. Although mammals do not produce chitin or its synthase, they express two active chitinases, chitotriosidase (Chit1 and acidic mammalian chitinase (AMCase. These mammalian chitinases have attracted considerable attention due to their increased expression in individuals with a number of pathological conditions, including Gaucher disease, Alzheimer's disease and asthma. However, the contribution of these enzymes to the pathophysiology of these diseases remains to be determined. The quantification of the Chit1 and AMCase mRNA levels and the comparison of those levels with the levels of well-known reference genes can generate useful and biomedically relevant information. In the beginning, we established a quantitative real-time PCR system that uses standard DNA produced by ligating the cDNA fragments of the target genes. This system enabled us to quantify and compare the expression levels of the chitinases and the reference genes on the same scale. We found that AMCase mRNA is synthesized at extraordinarily high levels in the mouse stomach. The level of this mRNA in the mouse stomach was 7- to 10-fold higher than the levels of the housekeeping genes and was comparable to that the level of the mRNA for pepsinogen C (progastricsin, a major component of the gastric mucosa. Thus, AMCase mRNA is a major transcript in mouse stomach, suggesting that AMCase functions as a digestive enzyme that breaks down polymeric chitin and as part of the host defense against chitin-containing pathogens in the gastric contents. Our methodology is applicable to the quantification of mRNAs for multiple genes across multiple specimens using the same scale.

  2. Acoustic Liner Drag: Measurements on Novel Facesheet Perforate Geometries

    Science.gov (United States)

    Howerton, Brian M.; Jones, Michael G.

    2016-01-01

    Interest in characterization of the aerodynamic drag of acoustic liners has increased in the past several years. This paper details experiments in the NASA Langley Grazing Flow Impedance Tube to quantify the relative drag of several perforate-over-honeycomb liner configurations at flow speeds of centerline flow Mach number equals 0.3 and 0.5. Various perforate geometries and orientations are investigated to determine their resistance factors using a static pressure drop approach. Comparison of these resistance factors gives a relative measurement of liner drag. For these same flow conditions, acoustic measurements are performed with tonal excitation from 400 to 3000 hertz at source sound pressure levels of 140 and 150 decibels. Educed impedance and attenuation spectra are used to determine the impact of variations in perforate geometry on acoustic performance.

  3. Drag Reduction by Riblets & Sharkskin Denticles: A Numerical Study

    Science.gov (United States)

    Boomsma, Aaron

    Riblet films are a passive method of turbulent boundary layer control that can reduce viscous drag. They have been studied with great detail for over 30 years. Although common riblet applications include flows with Adverse Pressure Gradients (APG), nearly all research thus far has been performed in channel flows. Recent research has provided motivation to study riblets in more complicated turbulent flows with claims that riblet drag reduction can double in mild APG common to airfoils at moderate angles of attack. Therefore, in this study, we compare drag reduction by scalloped riblet films between riblets in a zero pressure gradient and those in a mild APG using high-resolution large eddy simulations. In order to gain a fundamental understanding of the relationship between drag reduction and pressure gradient, we simulated several different riblet sizes that encompassed a broad range of s + (riblet width in wall units), similarly to many experimental studies. We found that there was only a slight improvement in drag reduction for riblets in the mild APG. We also observed that peak values of streamwise turbulence intensity, turbulent kinetic energy, and streamwise vorticity scale with riblet width. Primary Reynolds shear stresses and turbulence kinetic energy production however scale with the ability of the riblet to reduce skin-friction. Another turbulent roughness of similar shape and size to riblets is sharkskin. The hydrodynamic function of sharkskin has been under investigation for the past 30 years. Current literature conflicts on whether sharkskin is able to reduce skin friction similarly to riblets. To contribute insights toward reconciling these conflicting views, Direct Numerical Simulations (DNS) are carried out to obtain detailed flow fields around realistic denticles. A sharp interface immersed boundary method is employed to simulate two arrangements of actual sharkskin denticles (from Isurus oxyrinchus) in a turbulent boundary layer at Retau ≈ 180

  4. On the energy economics of air lubrication drag reduction

    Directory of Open Access Journals (Sweden)

    Simo A. Mäkiharju

    2012-12-01

    Full Text Available Air lubrication techniques for frictional drag reduction on ships have been proposed by numerous researchers since the 19th century. However, these techniques have not been widely adopted as questions persist about their drag reduction performance beyond the laboratory, as well as energy and economic cost-benefit. This paper draws on data from the literature to consider the suitability of air lubrication for large ocean going and U.S. Great Lakes ships, by establishing the basic energy economic calculations and presenting results for a hypothetical air lubricated ship. All the assumptions made in the course of the analysis are clearly stated so that they can be refined when considering application of air lubrication to a specific ship. The analysis suggests that, if successfully implemented, both air layer and partial cavity drag reduction could lead to net energy savings of 10 to 20%, with corresponding reductions in emissions.

  5. Flexural phonon limited phonon drag thermopower in bilayer graphene

    Science.gov (United States)

    Ansari, Mohd Meenhaz; Ashraf, SSZ

    2018-05-01

    We investigate the phonon drag thermopower from flexural phonons as a function of electron temperature and carrier concentration in the Bloch-Gruneisen regime in non-strained bilayer graphene using Boltzmann transport equation approach. The flexural phonons are expected to be the major source of intrinsic scattering mechanism in unstrained bilayer graphene due to their large density. The flexural phonon modes dispersion relation is quadratic so these low energy flexural phonons abound at room temperature and as a result deform the bilayer graphene sheet in the out of plane direction and affects the transport properties. We also produce analytical result for phonon-drag thermopower from flexural phonons and find that phonon-drag thermopower depicts T2 dependence on temperature and n-1 on carrier concentration.

  6. Spanwise drag variation on low Re wings -- revisited

    Science.gov (United States)

    Yang, Shanling; Spedding, Geoffrey

    2011-11-01

    Aerodynamic performance measurement and prediction of airfoils and wings at chord Reynolds numbers below 105 is both difficult and increasingly important in application to small-scale aircraft. Not only are the aerodynamics strongly affected by the dynamics of the unstable laminar boundary layer but the flow is decreasingly likely to be two-dimensional as Re decreases. The spanwise variation of the flow along a two-dimensional geometry is often held to be responsible for the large variations in measured profile drag coefficient. Here we measure local two-dimensional drag coefficients along a finite wing using non-intrusive PIV methods. Variations in Cd (y) can be related to local flow variations on the wing itself. Integrated values can be compared with force balance data, and the proper description of drag components at low Re will be discussed.

  7. The contact drag of towed demersal fishing gear components

    Science.gov (United States)

    O'Neill, F. G.; Summerbell, K.; Ivanović, A.

    2018-01-01

    The contact demersal towed fishing gears make with the seabed can lead to penetration of the substrate, lateral displacement of the sediment and a pressure field transmitted through the sediment. It will also contribute to the overall drag of the fishing gear. Consequently, there can be environmental effects such as habitat alteration and benthic mortality, and impacts to the fuel efficiency of the fishing operation which will affect emissions of nitrogen oxides, sulphur oxides and greenhouse gases such as CO2. Here we present the results of experimental trials that measure the contact drag of a range of elements that represent some of the components of towed demersal gears that are in contact with the seabed. We show that the contact drag of the gear components depends on their weight, geometry, the type of sediment on which they are towed and whether they are rolling or not. As expected, the contact drag of each gear component increases as its weight increases and the drag of fixed elements is greater than that of the rolling ones. The dependence on aspect ratio is more complex and the drag (per unit area) of narrow cylinders is less than that of wider ones when they roll on the finer sediment or are fixed (not permitted to roll) on the coarser sediment. When they roll on the coarse sediment there is no dependence on aspect ratio. Our results also suggest that fixed components may penetrate the seabed to a lesser depth when they are towed at higher speeds but when they roll there is no such relationship.

  8. Locus of the apices of projectile trajectories under constant drag

    Science.gov (United States)

    Hernández-Saldaña, H.

    2017-11-01

    Using the hodograph method, we present an analytical solution for projectile coplanar motion under constant drag, parametrised by the velocity angle. We find the locus formed by the apices of the projectile trajectories, and discuss its implementation for the motion of a particle on an inclined plane in presence of Coulomb friction. The range and time of flight are obtained numerically, and we find that the optimal launching angle is smaller than in the drag-free case. This is a good example of a problem with constant dissipation of energy that includes curvature; it is appropriate for intermediate courses of mechanics.

  9. The effects of Poynting–Robertson drag on solar sails

    Directory of Open Access Journals (Sweden)

    F.A. Abd El-Salam

    2018-06-01

    Full Text Available In the present work, the concept of solar sailing and its developing spacecraft are presented. The effects of Poynting–Robertson drag on solar sails are considered. Some analytical control laws with some mentioned input constraints for optimizing solar sails dynamics in heliocentric orbit using Lagrange’s planetary equations are obtained. Optimum force vector in a required direction is maximized by deriving optimal sail cone angle. New control laws that maximize thrust to obtain certain required maximization in some particular orbital element are obtained. Keywords: Poynting–Robertson drag, Solar sail, Control laws, Optimal sail, Cone angle

  10. A hypersonic lift mechanism with decoupled lift and drag surfaces

    Science.gov (United States)

    Xu, YiZhe; Xu, ZhiQi; Li, ShaoGuang; Li, Juan; Bai, ChenYuan; Wu, ZiNiu

    2013-05-01

    In the present study, we propose a novel lift mechanism for which the lifting surface produces only lift. This is achieved by mounting a two-dimensional shock-shock interaction generator below the lifting surface. The shock-shock interaction theory in conjunction with a three dimensional correction and checked with computational fluid dynamics (CFD) is used to analyze the lift and drag forces as function of the geometrical parameters and inflow Mach number. Through this study, though limited to only inviscid flow, we conclude that it is possible to obtain a high lift to drag ratio by suitably arranging the shock interaction generator.

  11. Development of drag disk and turbines at the INEL

    International Nuclear Information System (INIS)

    Goodrich, L.D.; Edson, J.L.; Averill, R.H.

    1984-01-01

    One of the parameters that must be measured in nuclear safety research is mass flow rate. The reactor environment associated with two-phase flow makes this measurement difficult. To accomplish this at the Idaho National Engineering Laboratory, a drag disk and turbine transducer conbination was developed. These transducers can withstand >2000 h of continuous operation in the reactor environment. Mechanical problems have been solved with these transducers to the point where the electrical coils are now the limiting factor on lifetime. This paper presents the results of the development of the drag disk and turbine with problems and solutions pointed out

  12. Drag force in a strongly coupled anisotropic plasma

    Science.gov (United States)

    Chernicoff, Mariano; Fernández, Daniel; Mateos, David; Trancanelli, Diego

    2012-08-01

    We calculate the drag force experienced by an infinitely massive quark propagating at constant velocity through an anisotropic, strongly coupled {N} = 4 plasma by means of its gravity dual. We find that the gluon cloud trailing behind the quark is generally misaligned with the quark velocity, and that the latter is also misaligned with the force. The drag coefficient μ can be larger or smaller than the corresponding isotropic value depending on the velocity and the direction of motion. In the ultra-relativistic limit we find that generically μ ∝ p. We discuss the conditions under which this behaviour may extend to more general situations.

  13. Control of the electromagnetic drag using fluctuating light fields

    Science.gov (United States)

    Pastor, Víctor J. López; Marqués, Manuel I.

    2018-05-01

    An expression for the electromagnetic drag force experienced by an electric dipole in a light field consisting of a monochromatic plane wave with polarization and phase randomly fluctuating is obtained. The expression explicitly considers the transformations of the field and frequency due to the Doppler shift and the change of the polarizability response of the electric dipole. The conditions to be fulfilled by the polarizability of the dipole in order to obtain a positive, a null, and a negative drag coefficient are analytically determined and checked against numerical simulations for the dynamics of a silver nanoparticle. The theoretically predicted diffusive, superdiffusive, and exponentially accelerated dynamical regimes are numerically confirmed.

  14. Determination of the drag resistance coefficients of different vehicles

    Science.gov (United States)

    Fahsl, Christoph; Vogt, Patrik

    2018-05-01

    While it has been demonstrated how air resistance could be analyzed by using mobile devices, this paper demonstrates a method of how to determine the drag resistance coefficient c of a commercial automobile by using the acceleration sensor of a smartphone or tablet. In an academic context, the drag resistance is often mentioned, but little attention is paid to quantitative measurements. This experiment was driven by the fact that this physical value is most certainly neglected because of its difficult measurability. In addition to that, this experiment gives insights on how the aerodynamic factor of an automobile affects the energy dissipation and thus how much power is required by automobile transportation.

  15. On the variability of sea drag in finite water depth

    Science.gov (United States)

    Toffoli, A.; Loffredo, L.; Le Roy, P.; LefèVre, J.-M.; Babanin, A. V.

    2012-11-01

    The coupling between the atmospheric boundary layer and the ocean surface in large-scale models is usually parameterized in terms of the sea drag coefficient, which is routinely estimated as a function of mean wind speed. The scatter of data around such parametric dependencies, however, is very significant and imposes a serious limitation on the forecasts and predictions that make use of sea surface drag parameterizations. The analysis of an atmospheric and wave data set collected in finite water depth at the Lake George measurement site (Australia) suggests that this variability relates to a number of parameters at the air-sea interface other than wind speed alone. In particular, results indicate that the sea drag depends on water depth and wave steepness, which make the wave profile more vertically asymmetric, and the concentration of water vapor in the air, which modifies air density and friction velocity. These dependencies are used to derive parametric functions based on the combined contribution of wind, waves and relative humidity. A standard statistical analysis confirms a substantial improvement in the prediction of the drag coefficient and sea surface roughness when additional parameters are taken into account.

  16. Measurements of the Drag Coefficient of Simulated Micrometeoroids

    Science.gov (United States)

    DeLuca, M.; Munsat, T.; Sternovsky, Z.

    2017-12-01

    The dust accelerator facility operated at the University of Colorado is used to simulate meteoric ablation, including measuring the ionization efficiency over a wide range of velocities (e.g., DeLuca et al., Planet. Space Sci., submitted, 2017). This presentation reports on the most recent experimental measurements of the drag coefficient that determines the particles' slowdown from their frictional interaction with the atmosphere. The measurements indicate that meteors experience considerably more slowdown than usually assumed. The simulated meteors consisted of submicron sized aluminum particles shot into an air chamber held at 200 mTorr pressure at velocities between 1 - 10 km/s using the dust accelerator and meteor ablation facility. The slowdown is calculated from precise timing measurements made using pickup tube detectors placed upstream and near the entrance to the air chamber, and an impact detector inside the air chamber at the downstream end of the chamber. Supporting modeling calculations show that the particles have little or no mass loss during their interaction with air and thus constant radius can be assumed. Preliminary results for the drag coefficient calculated from these timing measurements reveal that the aluminum particles have a drag coefficient of 1.51 ± 0.24 in air, which is higher than typically assumed in meteoric ablation models (usually 0.5 to 1), indicating that meteors may experience more air drag than previously assumed. More detailed measurements over a wider parameter range are underway.

  17. Investigation of drag effect using the field signature method

    International Nuclear Information System (INIS)

    Wan, Zhengjun; Liao, Junbi; Tian, Gui Yun; Cheng, Liang

    2011-01-01

    The potential drop (PD) method is an established non-destructive evaluation (NDE) technique. The monitoring of internal corrosion, erosion and cracks in piping systems, based on electrical field mapping or direct current potential drop array, is also known as the field signature method (FSM). The FSM has been applied in the field of submarine pipe monitoring and land-based oil and gas transmission pipes and containers. In the experimental studies, to detect and calculate the degree of pipe corrosion, the FSM analyses the relationships between the electrical resistance and pipe thickness using an electrode matrix. The relevant drag effect or trans-resistance will cause a large margin of error in the application of resistance arrays. It is the first time that the drag effect in the paper is investigated and analysed in resistance networks with the help of the FSM. Subsequently, a method to calculate the drag factors and eliminate its errors is proposed and presented. Theoretical analysis, simulation and experimental results show that the measurement accuracy can be improved by eliminating the errors caused by the drag effect

  18. Plasmon-mediated Coulomb drag between graphene waveguides

    DEFF Research Database (Denmark)

    Shylau, Artsem A.; Jauho, Antti-Pekka

    2014-01-01

    We analyze theoretically charge transport in Coulomb coupled graphene waveguides (GWGs). The GWGs are defined using antidot lattices, and the lateral geometry bypasses many technological challenges of earlier designs. The drag resistivity ρD, which is a measure of the many-particle interactions...

  19. Drag reduction of dense fine-grained slurries

    Czech Academy of Sciences Publication Activity Database

    Vlasák, Pavel; Chára, Zdeněk; Štern, Petr

    2010-01-01

    Roč. 58, č. 4 (2010), s. 261-270 ISSN 0042-790X R&D Projects: GA ČR(CZ) GAP105/10/1574 Institutional research plan: CEZ:AV0Z20600510 Keywords : kaolin slurry * drag reduction * experimental investigation * peptization * slurry rheology Subject RIV: BK - Fluid Dynamics Impact factor: 0.553, year: 2010

  20. Aerodynamic drag reduction tests on a box-shaped vehicle

    Science.gov (United States)

    Peterson, R. L.; Sandlin, D. R.

    1981-01-01

    The intent of the present experiment is to define a near optimum value of drag coefficient for a high volume type of vehicle through the use of a boattail, on a vehicle already having rounded front corners and an underbody seal, or fairing. The results of these tests will constitute a baseline for later follow-on studies to evaluate candidate methods of obtaining afterbody drag coefficients approaching the boattail values, but without resorting to such impractical afterbody extensions. The current modifications to the box-shaped vehicle consisted of a full and truncated boattail in conjunction with the faired and sealed underbody. Drag results from these configurations are compared with corresponding wind tunnel results of a 1/10 scale model. Test velocities ranged up to 96.6 km/h (60 mph) and the corresponding Reynolds numbers ranged up to 1.3 x 10 to the 7th power based on the vehicles length which includes the boattail. A simple coast-down technique was used to define drag.

  1. Experimental investigation of drag reduction by forward facing high ...

    Indian Academy of Sciences (India)

    Substantial aerodynamic drag, while flying at hypersonic Mach number, due to the presence of strong ... atmospheric flight of hypersonic vehicles, large-angle blunt-cone configurations are preferred at the cost of .... This paper is dedicated to Dr P R Viswanath for his contributions to experimental research in aerodynamics.

  2. Drag power kite with very high lift coefficient

    NARCIS (Netherlands)

    Bauer, F.; Kennel, R.M.; Hackl, C.M.; Campagnolo, F.; Patt, M.; Schmehl, R.

    2018-01-01

    As an alternative to conventional wind turbines, this study considered kites with onboard wind turbines driven by a high airspeed due to crosswind flight (“drag power”). The hypothesis of this study was, that if the kite's lift coefficient is maximized, then the power, energy yield, allowed costs

  3. Design and performance of the drag-disc turbine transducer

    International Nuclear Information System (INIS)

    Averill, R.H.; Goodrich, L.D.; Ford, R.E.

    1979-01-01

    Mass flow rates at the Loss-of-Fluid Test (LOFT) facility, EG and G Idaho, Inc., at the Idaho National Engineering Laboratory, are measured with the drag-disc turbine transducer (DTT). Operational description of the DTT and the developmental effort are discussed. Performance data and experiences with this transducer have been evaluated and are presented in this paper

  4. Investigation into the Mechanism of Polymer Thread Drag Reduction

    Science.gov (United States)

    1990-01-01

    They conducted experiments in a 3.75 cm diameter pipe, Re = 85,000, where they injected drag reducing solutions of guar gum and polyacrylamide, P-295 a...manufactured by Dow Chemical. Concentrations of 5000 ppm and 466 ppm based on weight were used in the experiments. The dry powder was suspended in 300

  5. Separability of drag and thrust in undulatory animals and machines

    Science.gov (United States)

    Bale, Rahul; Shirgaonkar, Anup A.; Neveln, Izaak D.; Bhalla, Amneet Pal Singh; Maciver, Malcolm A.; Patankar, Neelesh A.

    2014-12-01

    For nearly a century, researchers have tried to understand the swimming of aquatic animals in terms of a balance between the forward thrust from swimming movements and drag on the body. Prior approaches have failed to provide a separation of these two forces for undulatory swimmers such as lamprey and eels, where most parts of the body are simultaneously generating drag and thrust. We nonetheless show that this separation is possible, and delineate its fundamental basis in undulatory swimmers. Our approach unifies a vast diversity of undulatory aquatic animals (anguilliform, sub-carangiform, gymnotiform, bal-istiform, rajiform) and provides design principles for highly agile bioinspired underwater vehicles. This approach has practical utility within biology as well as engineering. It is a predictive tool for use in understanding the role of the mechanics of movement in the evolutionary emergence of morphological features relating to locomotion. For example, we demonstrate that the drag-thrust separation framework helps to predict the observed height of the ribbon fin of electric knifefish, a diverse group of neotropical fish which are an important model system in sensory neurobiology. We also show how drag-thrust separation leads to models that can predict the swimming velocity of an organism or a robotic vehicle.

  6. Deconstructing Hub Drag. Part 2. Computational Development and Anaysis

    Science.gov (United States)

    2013-09-30

    leveraged a Vertical Lift Consortium ( VLC )-funded hub drag scaling research effort. To confirm this objective, correlations are performed with the...Technology™ Demonstrator aircraft using an unstructured computational solver. These simpler faired elliptical geome- tries can prove to be challenging ...possible. However, additional funding was obtained from the Vertical Lift Consortium ( VLC ) to perform this study. This analysis is documented in

  7. Clock transport synchronisation and the dragging of inertial frames

    International Nuclear Information System (INIS)

    Rosenblum, Arnold

    1987-01-01

    It is shown that it is possible, by using the lack of synchronisation of clocks by clock transport synchronisation in circular orbits, to test for the dragging of inertial frames in Einstein's theory of general relativity. Possible experiments are discussed. (author)

  8. Drag reduction of nata de coco suspensions in circular pipe flow

    Science.gov (United States)

    Warashina, J.; Ogata, S.

    2015-04-01

    Reducing pipe friction by adding a drag-reducing agent has attracted interest as a means to reduce energy consumption. In addition to reducing drag, these agents are required to have a low environmental load and conserve natural resources. However, no drag-reducing agent currently satisfies both these conditions. We focused on nata de coco and found that the nata de coco fiber reduced drag by up to 25%. With respect to the mechanism of drag reduction by nata de coco fiber, the relationship between drag-reduction phenomena and the fiber form of nata de coco was investigated by visualization. We also found that the drag-reduction effect appeared to be due to the formation of networks of tangled fibers of nata de coco. However, drag reduction did not occur in the case in which fibers of nata de coco did not form networks.

  9. An Aerodynamic Database for the Mk 82 General Purpose Low Drag Bomb

    National Research Council Canada - National Science Library

    Krishnamoorthy, L

    1997-01-01

    The drag database of the Mk 82 General Purpose Low Drag bomb, the primary gravity weapon in the RAAF inventory, has some shortcomings in the quality and traceability of data, and in the variations due...

  10. Quantifying drag on wellbore casings in moving salt sheets

    Science.gov (United States)

    Weijermars, R.; Jackson, M. P. A.; Dooley, T. P.

    2014-08-01

    Frontier hydrocarbon development projects in the deepwater slopes of the Gulf of Mexico Basin, Santos Basin and Lower Congo Basin all require wells to cross ductile layers of autochthonous or allochthonous salt moving at peak rates of 100 mm yr-1. The Couette-Poiseuille number is introduced here to help pinpoint the depth of shear stress reversal in such salt layers. For any well-planned through salt, the probable range of creep forces of moving salt needs to be taken into account when designing safety margins and load-factor tolerance of the well casing. Drag forces increase with wellbore diameter, but more significantly with effective viscosity and speed of the creeping salt layer. The potential drag forces on cased wellbores in moving salt sheets are estimated analytically using a range of salt viscosities (1015-1019 Pa s) and creep rates (0-10 mm yr-1). Drag on perfectly rigid casing of infinite strength may reach up to 13 Giga Newton per meter wellbore length in salt having a viscosity of 1019 Pa s. Well designers may delay stress accumulations due to salt drag when flexible casing accommodates some of the early displacement and strain. However, all creeping salt could displace, fracture and disconnect well casing, eventually. The shear strength of typical heavy duty well casing (about 1000 MPa) can be reached due to drag by moving salt. Internal flow of salt will then fracture the casing near salt entry and exit points, but the structural damage is likely to remain unnoticed early in the well-life when the horizontal shift of the wellbore is still negligibly small (at less than 1 cm yr-1). Disruption of casing and production flow lines within the anticipated service lifetime of a well remains a significant risk factor within distinct zones of low-viscosity salt which may reach ultrafast creep rates of 100 mm yr-1.

  11. Mechanism of drag reduction for circular cylinders with patterned surface

    International Nuclear Information System (INIS)

    Butt, U.; Jehring, L.; Egbers, C.

    2014-01-01

    Highlights: • Reduced drag of patterned cylinders over a wide range of Re numbers. • Hexagonal patterns cannot be characterized as roughness structures. • Hexagonal bumps affect the flow like spherical dimples of smaller k/d ratio do. • Main separation is delayed caused by a partial separation. • Angle of a separation line is not constant over the length of cylinder. -- Abstract: In this paper, the flow over cylinders with a patterned surface (k/d = 1.98 × 10 −2 ) is investigated in a subsonic wind tunnel over Reynolds numbers ranging from 3.14 × 10 4 to 2.77 × 10 5 by measuring drag, flow visualization and measuring velocity profiles above the surface of the cylinders, to observe the effect of hexagonal patterns on the flow of air. These patterns can also be referred as hexagonal dimples or bumps depending on their configuration. The investigations revealed that a patterned cylinder with patterns pressed outwards has a drag coefficient of about 0.65 times of a smooth one. Flow visualization techniques including surface oil-film technique and velocity profile measurement were employed to elucidate this effect, and hence present the mechanism of drag reduction. The measurement of velocity profiles using hot-wire anemometry above the surface reveal that a hexagonal bump cause local separation generating large turbulence intensity along the separating shear layer. Due to this increased turbulence, the flow reattaches to the surface with higher momentum and become able to withstand the pressure gradient delaying the main separation significantly. Besides that, the separation does not appear to occur in a straight line along the length of the cylinder as in case of most passive drag control methods, but follow exactly the hexagonal patterns forming a wave with its crest at 115° and trough at 110°, in contrast to the laminar separation line at 85° for a smooth cylinder

  12. Tracking Human Immunodeficiency Virus-1 Infection in the Humanized DRAG Mouse Model

    OpenAIRE

    Jiae Kim; Jiae Kim; Kristina K. Peachman; Kristina K. Peachman; Ousman Jobe; Ousman Jobe; Elaine B. Morrison; Atef Allam; Atef Allam; Linda Jagodzinski; Sofia A. Casares; Mangala Rao

    2017-01-01

    Humanized mice are emerging as an alternative model system to well-established non-human primate (NHP) models for studying human immunodeficiency virus (HIV)-1 biology and pathogenesis. Although both NHP and humanized mice have their own strengths and could never truly reflect the complex human immune system and biology, there are several advantages of using the humanized mice in terms of using primary HIV-1 for infection instead of simian immunodeficiency virus or chimera simian/HIV. Several...

  13. How to drag with a worn-out mouse? Searching for social justice through collaboration

    DEFF Research Database (Denmark)

    Penteado, Miriam Godoy; Skovsmose, Ole

    2009-01-01

    We consider what a concern for social justice in terms of social inclusion might mean for teacher education, both practising and prospective, with particular reference to the use of information and communication technology (ICT) in mathematics education taking place at a borderland school. Our...... discussion proceeds through the following steps: (1) We explore what a borderland position might denote to address what social inclusion might mean. (2) We consider the significance of mathematics education and the use of ICT for processes of social inclusion. (3) We briefly refer to the Interlink Network......, as many of our observations emerge as reflections on this project. (4) We present different issues that will be of particular importance with respect to teacher education if we want to establish a mathematics education for social inclusion. These issues concern moving away from the comfort zone...

  14. Intelligent Control for Drag Reduction on the X-48B Vehicle

    Science.gov (United States)

    Griffin, Brian Joseph; Brown, Nelson Andrew; Yoo, Seung Yeun

    2011-01-01

    This paper focuses on the development of an intelligent control technology for in-flight drag reduction. The system is integrated with and demonstrated on the full X-48B nonlinear simulation. The intelligent control system utilizes a peak-seeking control method implemented with a time-varying Kalman filter. Performance functional coordinate and magnitude measurements, or independent and dependent parameters respectively, are used by the Kalman filter to provide the system with gradient estimates of the designed performance function which is used to drive the system toward a local minimum in a steepestdescent approach. To ensure ease of integration and algorithm performance, a single-input single-output approach was chosen. The framework, specific implementation considerations, simulation results, and flight feasibility issues related to this platform are discussed.

  15. Effects of single and split doses of cobalt-60 gamma rays and 14 MeV neutrons on mouse stem cell spermatogonia.

    Science.gov (United States)

    Hacker-Klom, U B; Köhnlein, W; Göhde, W

    2000-12-01

    The long-term effects of ionizing radiation on male gonads may be the result of damage to spermatogonial stem cells. Doses of 10 cGy to 15 Gy (60)Co gamma rays or 10 cGy to 7 Gy 14 MeV neutrons were given to NMRI mice as single or split doses separated by a 24-h interval. The ratios of haploid spermatids/2c cells and the coefficients of variation of DNA histogram peaks as measures of both the cytocidal and the clastogenic actions of radiation were analyzed by DNA flow cytometry after DAPI staining. The coefficient of variation is not only a statistical examination of the data but is also used here as a measure of residual damage to DNA (i.e. a biological dosimeter). Testicular histology was examined in parallel. At 70 days after irradiation, the relative biological effectiveness for neutrons at 50% survival of spermatogonial stem cells was 3.6 for single doses and 2.8 for split doses. The average coefficient of variation of unirradiated controls of elongated spermatids was doubled when stem cells were irradiated with single doses of approximately 14 Gy (60)Co gamma rays or 3 Gy neutrons and observed 70 days later. Split doses of (60)Co gamma rays were more effective than single doses, doubling DNA dispersion at 7 Gy. No fractionation effect was found with neutrons with coefficients of variation.

  16. Atmospheric Drag, Occultation ‘N’ Ionospheric Scintillation (ADONIS mission proposal

    Directory of Open Access Journals (Sweden)

    Hettrich Sebastian

    2015-01-01

    Full Text Available The Atmospheric Drag, Occultation ‘N’ Ionospheric Scintillation mission (ADONIS studies the dynamics of the terrestrial thermosphere and ionosphere in dependency of solar events over a full solar cycle in Low Earth Orbit (LEO. The objectives are to investigate satellite drag with in-situ measurements and the ionospheric electron density profiles with radio occultation and scintillation measurements. A constellation of two satellites provides the possibility to gain near real-time data (NRT about ionospheric conditions over the Arctic region where current coverage is insufficient. The mission shall also provide global high-resolution data to improve assimilative ionospheric models. The low-cost constellation can be launched using a single Vega rocket and most of the instruments are already space-proven allowing for rapid development and good reliability. From July 16 to 25, 2013, the Alpbach Summer School 2013 was organised by the Austrian Research Promotion Agency (FFG, the European Space Agency (ESA, the International Space Science Institute (ISSI and the association of Austrian space industries Austrospace in Alpbach, Austria. During the workshop, four teams of 15 students each independently developed four different space mission proposals on the topic of “Space Weather: Science, Missions and Systems”, supported by a team of tutors. The present work is based on the mission proposal that resulted from one of these teams’ efforts.

  17. A novel transferable individual tree crown delineation model based on Fishing Net Dragging and boundary classification

    Science.gov (United States)

    Liu, Tao; Im, Jungho; Quackenbush, Lindi J.

    2015-12-01

    This study provides a novel approach to individual tree crown delineation (ITCD) using airborne Light Detection and Ranging (LiDAR) data in dense natural forests using two main steps: crown boundary refinement based on a proposed Fishing Net Dragging (FiND) method, and segment merging based on boundary classification. FiND starts with approximate tree crown boundaries derived using a traditional watershed method with Gaussian filtering and refines these boundaries using an algorithm that mimics how a fisherman drags a fishing net. Random forest machine learning is then used to classify boundary segments into two classes: boundaries between trees and boundaries between branches that belong to a single tree. Three groups of LiDAR-derived features-two from the pseudo waveform generated along with crown boundaries and one from a canopy height model (CHM)-were used in the classification. The proposed ITCD approach was tested using LiDAR data collected over a mountainous region in the Adirondack Park, NY, USA. Overall accuracy of boundary classification was 82.4%. Features derived from the CHM were generally more important in the classification than the features extracted from the pseudo waveform. A comprehensive accuracy assessment scheme for ITCD was also introduced by considering both area of crown overlap and crown centroids. Accuracy assessment using this new scheme shows the proposed ITCD achieved 74% and 78% as overall accuracy, respectively, for deciduous and mixed forest.

  18. WE-AB-204-12: Dosimetry at the Sub-Cellular Scale of Auger-Electron Emitter 99m-Tc in a Mouse Single Thyroid Follicle Model

    Energy Technology Data Exchange (ETDEWEB)

    Taborda, A; Benabdallah, N; Desbree, A [Institut de Radioprotection et de Surete Nucleaire, Fontenay-aux-roses (France)

    2015-06-15

    Purpose: To perform a dosimetry study at the sub-cellular scale of Auger-electron emitter 99m-Tc using a mouse single thyroid cellular model to investigate the contribution of the 99m-Tc Auger-electrons to the absorbed dose and possible link to the thyroid stunning in in vivo experiments in mice, recently reported in literature. Methods: The simulation of S-values for Auger-electron emitting radionuclides was performed using both the recent MCNP6 software and the Geant4-DNA extension of the Geant4 toolkit. The dosimetric calculations were validated through comparison with results from literature, using a simple model of a single cell consisting of two concentric spheres of unit density water and for six Auger-electron emitting radionuclides. Furthermore, the S-values were calculated using a single thyroid follicle model for uniformly distributed 123-I and 125-I radionuclides and compared with published S-values. After validation, the simulation of the S-values was performed for the 99m-Tc radionuclide within the several mouse thyroid follicle cellular compartments, considering the radiative and non-radiative transitions of the 99m-Tc radiation spectrum. Results: The calculated S-values using MCNP6 are in good agreement with the results from literature, validating its use for the 99m-Tc S-values calculations. The most significant absorbed dose corresponds to the case where the radionuclide is uniformly distributed in the follicular cell’s nucleus, with a S-value of 7.8 mGy/disintegration, due mainly to the absorbed Auger-electrons. The results show that, at a sub-cellular scale, the emitted X-rays and gamma particles do not contribute significantly to the absorbed dose. Conclusion: In this work, MCNP6 was validated for dosimetric studies at the sub-cellular scale. It was shown that the contribution of the Auger-electrons to the absorbed dose is important at this scale compared to the emitted photons’ contribution and can’t be neglected. The obtained S

  19. Moffies, artists, and queens: race and the production of South African gay male drag.

    Science.gov (United States)

    Swarr, Amanda Lock

    2004-01-01

    This article draws on seventeen months of ethnographic fieldwork in South Africa to explore the experiences of urban and township drag performers. I show that two distinct sex-gender-sexuality systems have emerged based in the sociopolitical history of South Africa, and I argue that urban drag produces race oppositionally and examine how township femininity creates raced forms of gender, sex, and sexuality. Contemporary South African drag foregrounds the performativity and constitution of race and gender. My analysis attempts to challenge definitions of "drag" and "audience," suggesting the necessity for an integrated reconceptualization of drag studies.

  20. Experimental Investigation of the Fresnel Drag Effect in RF Coaxial Cables

    Directory of Open Access Journals (Sweden)

    Brotherton D.

    2011-01-01

    Full Text Available An experiment that confirms the Fresnel drag formalism in RF coaxial cables is reported. The Fresnel "drag" in bulk dielectrics and in optical fibers has previously been well established. An explanation for this formalism is given, and it is shown that there is no actual drag phenomenon, rather that the Fresnel drag effect is merely the consequence of a simplified description of EM scattering within a dielectric in motion wrt the dynamical 3-space. The Fresnel drag effect plays a critical role in the design of various light-speed anisotropy detectors.

  1. Controlling turbulent drag across electrolytes using electric fields.

    Science.gov (United States)

    Ostilla-Mónico, Rodolfo; Lee, Alpha A

    2017-07-01

    Reversible in operando control of friction is an unsolved challenge that is crucial to industrial tribology. Recent studies show that at low sliding velocities, this control can be achieved by applying an electric field across electrolyte lubricants. However, the phenomenology at high sliding velocities is yet unknown. In this paper, we investigate the hydrodynamic friction across electrolytes under shear beyond the transition to turbulence. We develop a novel, highly parallelised numerical method for solving the coupled Navier-Stokes Poisson-Nernst-Planck equation. Our results show that turbulent drag cannot be controlled across dilute electrolytes using static electric fields alone. The limitations of the Poisson-Nernst-Planck formalism hint at ways in which turbulent drag could be controlled using electric fields.

  2. Intershell resistance in multiwall carbon nanotubes: A Coulomb drag study

    DEFF Research Database (Denmark)

    Lunde, Anders Mathias; Flensborg, Karsten; Jauho, Antti-Pekka

    2005-01-01

    We calculate the intershell resistance R-21 in a multiwall carbon nanotube as a function of temperature T and Fermi level epsilon(F) (e.g., a gate voltage), varying the chirality of the inner and outer tubes. This is done in a so-called Coulomb drag setup, where a current I-1 in one shell induces...... a voltage drop V-2 in another shell by the screened Coulomb interaction between the shells neglecting the intershell tunneling. We provide benchmark results for R-21 = V2/I-1 within the Fermi liquid theory using Boltzmann equations. The band structure gives rise to strongly chirality-dependent suppression...... effects for the Coulomb drag between different tubes due to selection rules combined with mismatching of wave vector and crystal angular momentum conservation near the Fermi level. This gives rise to orders of magnitude changes in R-21 and even the sign of R-21 can change depending on the chirality...

  3. Wave drag reduction due to a self-aligning aerodisk

    Science.gov (United States)

    Schnepf, Ch.; Wysocki, O.; Schülein, E.

    2015-06-01

    The effect of a self-aligning aerodisk on the wave drag of a blunt slender body in a pitching maneuver has been numerically investigated. The self-alignment was realized by a coupling of the flow solver and a flight mechanics tool. The slender body was pitched with high repetition rate between α = 0° and 20° at M = 1.41. Even at high α, the concept could align the aerodisk to the oncoming flow. In comparison to the reference body without a self-aligning aerodisk, a distinct drag reduction is achieved. A comparison with existing experimental data shows a qualitatively good agreement considering the shock and separation structure and the kinematics of the aerodisk.

  4. Bioinspired superhydrophobic, self-cleaning and low drag surfaces

    Science.gov (United States)

    Bhushan, Bharat

    2013-09-01

    Nature has evolved objects with desired functionality using commonly found materials. Nature capitalizes on hierarchical structures to achieve functionality. The understanding of the functions provided by objects and processes found in nature can guide us to produce nanomaterials, nanodevices, and processes with desirable functionality. This article provides an overview of four topics: (1) Lotus Effect used to develop superhydrophobic and self-cleaning/antifouling surfaces with low adhesion, (2) Shark Skin Effect to develop surfaces with low fluid drag and anti-fouling characteristics, and (3-4) Rice Leaf and Butterfly Wing Effect to develop superhydrophobic and self-cleaning surfaces with low drag. Rice Leaf and Butterfly Wings combine the Shark Skin and Lotus Effects.

  5. Collisionless ion drag force on a spherical grain

    International Nuclear Information System (INIS)

    Hutchinson, I H

    2006-01-01

    The ion drag force on a spherical grain situated in a flowing collisionless plasma is obtained from the specialized coordinate electrostatic particle and thermals in cell simulation code (SCEPTIC) (Hutchinson 2002 Plasma Phys. Control. Fusion 44 1953, Hutchinson 2003 Plasma Phys. Control. Fusion 45 1477, Hutchinson 2005 Plasma Phys. Control. Fusion 47 71) and compared with recent analytic approximate treatments in the interesting and relevant case when the Debye length is only moderately larger than the sphere radius. There is a substantial complex structure in the results for transonic flows, which is explained in terms of the details of ion orbits. Naturally the prior analytic approximations miss this structure, and as a result they seriously underestimate the drag for speeds near the sound speed. An easy-to-evaluate expression for force is provided that fits the comprehensive results of the code. This expression, with minor modification, also fits the results even for Debye length much smaller than the sphere radius

  6. Drag reduction by dimples? - A complementary experimental/numerical investigation

    International Nuclear Information System (INIS)

    Lienhart, Hermann; Breuer, Michael; Koeksoy, Cagatay

    2008-01-01

    The paper is concerned with an experimental and numerical investigation of the turbulent flow over dimpled surfaces. Shallow dimples distributed regularly over the wall of a plane channel with large aspect ratio are used to study their effect on the friction drag. The resulting pressure drop in the channel was measured for smooth and dimpled walls. In addition to these investigations on internal flows, an external flow study was performed and boundary-layer profiles were measured using a Pitot-tube rake. Complementary to the measurements, direct numerical simulations for the internal flow configuration with and without dimples were carried out for two different grid resolutions and analyzed in detail. The objective was to clarify whether or not dimples cause reduction of the skin-friction drag

  7. Suboptimal control for drag reduction in turbulent pipe flow

    International Nuclear Information System (INIS)

    Choi, Jung Il; Sung, Hyung Jin; Xu, Chun Xiao

    2001-01-01

    A suboptimal control law in turbulent pipe flow is derived and tested. Two sensing variables ∂ρ/∂θ / w and ∂ν θ /∂r / w are applied with two actuations φ θ and φ γ . To test the suboptimal control law, direct numerical simulations of turbulent pipe flow at Re τ =150 are performed. When the control law is applied, a 13∼23% drag reduction is achieved. The most effective drag reduction is made at the pair of ∂υ θ /∂r / w and φ γ . An impenetrable virtual wall concept is useful for analyzing the near-wall suction and blowing. The virtual wall concept is useful for analyzing the near-wall behavior of the controlled flow. Comparison of the present suboptimal control with that of turbulent channel flow reveals that the curvature effect is insignificant

  8. Simultaneous drag and flow measurements of Olympic skeleton athletes

    Science.gov (United States)

    Moon, Yae Eun; Digiulio, David; Peters, Steve; Wei, Timothy

    2009-11-01

    The Olympic sport of skeleton involves an athlete riding a small sled face first down a bobsled track at speeds up to 130 km/hr. In these races, the difference between gold and missing the medal stand altogether can be hundredths of a second per run. As such, reducing aerodynamic drag through proper body positioning is of first order importance. To better study the flow behavior and to improve the performance of the athletes, we constructed a static force balance system on a mock section of a bobsled track. Athlete and the sled are placed on the force balance system which is positioned at the exit of an open loop wind tunnel. Simultaneous drag force and DPIV velocity field measurements were made along with video recordings of body position to aid the athletes in determining their optimal aerodynamic body position.

  9. Physics and control of wall turbulence for drag reduction.

    Science.gov (United States)

    Kim, John

    2011-04-13

    Turbulence physics responsible for high skin-friction drag in turbulent boundary layers is first reviewed. A self-sustaining process of near-wall turbulence structures is then discussed from the perspective of controlling this process for the purpose of skin-friction drag reduction. After recognizing that key parts of this self-sustaining process are linear, a linear systems approach to boundary-layer control is discussed. It is shown that singular-value decomposition analysis of the linear system allows us to examine different approaches to boundary-layer control without carrying out the expensive nonlinear simulations. Results from the linear analysis are consistent with those observed in full nonlinear simulations, thus demonstrating the validity of the linear analysis. Finally, fundamental performance limit expected of optimal control input is discussed.

  10. Effect of truncated cone roughness element density on hydrodynamic drag

    Science.gov (United States)

    Womack, Kristofer; Schultz, Michael; Meneveau, Charles

    2017-11-01

    An experimental study was conducted on rough-wall, turbulent boundary layer flow with roughness elements whose idealized shape model barnacles that cause hydrodynamic drag in many applications. Varying planform densities of truncated cone roughness elements were investigated. Element densities studied ranged from 10% to 79%. Detailed turbulent boundary layer velocity statistics were recorded with a two-component LDV system on a three-axis traverse. Hydrodynamic roughness length (z0) and skin-friction coefficient (Cf) were determined and compared with the estimates from existing roughness element drag prediction models including Macdonald et al. (1998) and other recent models. The roughness elements used in this work model idealized barnacles, so implications of this data set for ship powering are considered. This research was supported by the Office of Naval Research and by the Department of Defense (DoD) through the National Defense Science & Engineering Graduate Fellowship (NDSEG) Program.

  11. Reducing Aerodynamic Drag on Empty Open Cargo Vehicles

    Science.gov (United States)

    Ross, James C.; Storms, Bruce L.; Dzoan, Dan

    2009-01-01

    Some simple structural modifications have been demonstrated to be effective in reducing aerodynamic drag on vehicles that have empty open cargo bays. The basic idea is to break up the airflow in a large open cargo bay by inserting panels to divide the bay into a series of smaller bays. In the case of a coal car, this involves inserting a small number (typically between two and four) of vertical full-depth or partial-depth panels.

  12. The effects of Poynting-Robertson drag on solar sails

    Science.gov (United States)

    Abd El-Salam, F. A.

    2018-06-01

    In the present work, the concept of solar sailing and its developing spacecraft are presented. The effects of Poynting-Robertson drag on solar sails are considered. Some analytical control laws with some mentioned input constraints for optimizing solar sails dynamics in heliocentric orbit using Lagrange's planetary equations are obtained. Optimum force vector in a required direction is maximized by deriving optimal sail cone angle. New control laws that maximize thrust to obtain certain required maximization in some particular orbital element are obtained.

  13. Stokes’ and Lamb's viscous drag laws

    International Nuclear Information System (INIS)

    Eames, I; Klettner, C A

    2017-01-01

    Since Galileo used his pulse to measure the time period of a swinging chandelier in the 17th century, pendulums have fascinated scientists. It was not until Stokes' (1851 Camb. Phil. Soc. 9 8–106) (whose interest was spurred by the pendulur time pieces of the mid 19th century) treatise on viscous flow that a theoretical framework for the drag on a sphere at low Reynolds number was laid down. Stokes' famous drag law has been used to determine two fundamental physical constants—the charge on an electron and Avogadro's constant—and has been used in theories which have won three Nobel prizes. Considering its illustrious history it is then not surprising that the flow past a sphere and its two-dimensional analog, the flow past a cylinder, form the starting point of teaching flow past a rigid body in undergraduate level fluid mechanics courses. Usually starting with the two-dimensional potential flow past a cylinder, students progress to the three-dimensional potential flow past a sphere. However, when the viscous flow past rigid bodies is taught, the three-dimensional example of a sphere is first introduced, and followed by (but not often), the two-dimensional viscous flow past a cylinder. The reason why viscous flow past a cylinder is generally not taught is because it is usually explained from an asymptotic analysis perspective. In fact, this added mathematical complexity is why the drag on a cylinder was only solved in 1911, 60 years after the drag on a sphere. In this note, we show that the viscous flow past a cylinder can be explained without the need to introduce any asymptotic analysis while still capturing all the physical insight of this classic fluid mechanics problem. (paper)

  14. Thermal lift generation and drag reduction in rarefied aerodynamics

    Science.gov (United States)

    Pekardan, Cem; Alexeenko, Alina

    2016-11-01

    With the advent of the new technologies in low pressure environments such as Hyperloop and helicopters designed for Martian applications, understanding the aerodynamic behavior of airfoils in rarefied environments are becoming more crucial. In this paper, verification of rarefied ES-BGK solver and ideas such as prediction of the thermally induced lift and drag reduction in rarefied aerodynamics are investigated. Validation of the rarefied ES-BGK solver with Runge-Kutta discontinous Galerkin method with experiments in transonic regime with a Reynolds number of 73 showed that ES-BGK solver is the most suitable solver in near slip transonic regime. For the quantification of lift generation, A NACA 0012 airfoil is studied with a high temperature surface on the bottom for the lift creation for different Knudsen numbers. It was seen that for lower velocities, continuum solver under predicts the lift generation when the Knudsen number is 0.00129 due to local velocity gradients reaching slip regime although lift coefficient is higher with the Boltzmann ES-BGK solutions. In the second part, the feasibility of using thermal transpiration for drag reduction is studied. Initial study in drag reduction includes an application of a thermal gradient at the upper surface of a NACA 0012 airfoil near trailing edge at a 12-degree angle of attack and 5 Pa pressure. It was seen that drag is reduced by 4 percent and vortex shedding frequency is reduced due to asymmetry introduced in the flow due to temperature gradient causing reverse flow due to thermal transpiration phenomena.

  15. Biomimetics inspired surfaces for drag reduction and oleophobicity/philicity

    Directory of Open Access Journals (Sweden)

    Bharat Bhushan

    2011-02-01

    Full Text Available The emerging field of biomimetics allows one to mimic biology or nature to develop nanomaterials, nanodevices, and processes which provide desirable properties. Hierarchical structures with dimensions of features ranging from the macroscale to the nanoscale are extremely common in nature and possess properties of interest. There are a large number of objects including bacteria, plants, land and aquatic animals, and seashells with properties of commercial interest. Certain plant leaves, such as lotus (Nelumbo nucifera leaves, are known to be superhydrophobic and self-cleaning due to the hierarchical surface roughness and presence of a wax layer. In addition to a self-cleaning effect, these surfaces with a high contact angle and low contact angle hysteresis also exhibit low adhesion and drag reduction for fluid flow. An aquatic animal, such as a shark, is another model from nature for the reduction of drag in fluid flow. The artificial surfaces inspired from the shark skin and lotus leaf have been created, and in this article the influence of structure on drag reduction efficiency is reviewed. Biomimetic-inspired oleophobic surfaces can be used to prevent contamination of the underwater parts of ships by biological and organic contaminants, including oil. The article also reviews the wetting behavior of oil droplets on various superoleophobic surfaces created in the lab.

  16. The influence of numerical models on determining the drag coefficient

    Directory of Open Access Journals (Sweden)

    Dobeš Josef

    2014-03-01

    Full Text Available The paper deals with numerical modelling of body aerodynamic drag coefficient in the transition from laminar to turbulent flow regimes, where the selection of a suitable numerical model is problematic. On the basic problem of flow around a simple body – sphere selected computational models are tested. The values obtained by numerical simulations of drag coefficients of each model are compared with the graph of dependency of the drag coefficient vs. Reynolds number for a sphere. Next the dependency of Strouhal number vs. Reynolds number is evaluated, where the vortex shedding frequency values for given speed are obtained numerically and experimentally and then the values are compared for each numerical model and experiment. The aim is to specify trends for the selection of appropriate numerical model for flow around bodies problem in which the precise description of the flow field around the obstacle is used to define the acoustic noise source. Numerical modelling is performed by finite volume method using CFD code.

  17. Drag reduction: enticing turbulence, and then an industry.

    Science.gov (United States)

    Spalart, Philippe R; McLean, J Douglas

    2011-04-13

    We examine drag-reduction proposals, as presented in this volume and in general, first with concrete examples of how to bridge the distance from pure science through engineering to what makes inventions go into service; namely, the value to the public. We point out that the true drag reduction can be markedly different from an estimate based simply on the difference between turbulent and laminar skin friction over the laminarized region, or between the respective skin frictions of the baseline and the riblet-treated flow. In some situations, this difference is favourable, and is due to secondary differences in pressure drag. We reiterate that the benefit of riblets, if it is expressed as a percentage in skin-friction reduction, is unfortunately lower at full-size Reynolds numbers than in a small-scale experiment or simulation. The Reynolds number-independent measure of such benefits is a shift of the logarithmic law, or 'ΔU(+)'. Anticipating the design of a flight test and then a product, we note the relative ease in representing riblets or laminarization in computational fluid dynamics, in contrast with the huge numerical and turbulence-modelling challenge of resolving active flow control systems in a calculation of the full flow field. We discuss in general terms the practical factors that have limited applications of concepts that would appear more than ready after all these years, particularly riblets and laminar-flow control.

  18. Drag reduction of a reverse-engineered vehicle

    Energy Technology Data Exchange (ETDEWEB)

    Lecrivain, G.; Slaouti, A.; Kennedy, I. [Manchester Metropolitan Univ., Manchester (United Kingdom). Dept. of Engineering and Technology

    2007-08-09

    The aerodynamic performance of a hand-made sports car was numerically assessed using computational fluid dynamics (CFD) analysis of various shape modifications. The purpose was to achieve a lower drag design. Reverse-engineering was used to create a virtual model of complex 3D shapes for which no computer-aided drawings (CAD) data existed. From the predicted flow, the body could be redesigned for better performance prior to its remanufacturing. This paper described the multidisciplinary procedure involving reverse-engineering and CAD that was used to recreate a suitable watertight model of the sports car. The different errors embedded in the successive stages leading to the final model were accurately assessed and minimized. The whole vehicle was remodelled for drag reduction. Surface reconstruction was carried out, an an accurate set of high quality Non-Uniform Rational B-Spline (NURBS) surfaces was produced over the polygonal mesh resulting in a fine visual surface finish with smooth lines and contours, as required in the automotive industry. Further modifications were implemented for the purpose of drag reduction and to improve its aerodynamic performance. The application described in this paper can be extended to any other similarly intricate vehicle or industrial component. 12 refs., 1 tab., 11 figs.

  19. Aerodynamic drag control by pulsed jets on simplified car geometry

    Science.gov (United States)

    Gilliéron, Patrick; Kourta, Azeddine

    2013-02-01

    Aerodynamic drag control by pulsed jets is tested in a wind tunnel around a simplified car geometry named Ahmed body with a rear slant angle of 35°. Pulsed jet actuators are located 5 × 10-3 m from the top of the rear window. These actuators are produced by a pressure difference ranging from 1.5 to 6.5 × 105 Pa. Their excitation frequency can vary between 10 and 550 Hz. The analysis of the control effects is based on wall visualizations, aerodynamic drag coefficient measurements, and the velocity fields obtained by 2D PIV measurements. The maximum drag reduction is 20 % and is obtained for the excitation frequency F j = 500 Hz and for the pressure difference ∆ P = 1.5 × 105 Pa. This result is linked with a substantial reduction in the transverse development of the longitudinal vortex structures coming from the left and right lateral sides of the rear window, with a displacement of the vortex centers downstream and with a decrease in the transverse rotational absolute values of these structures.

  20. The elaborate plumage in peacocks is not such a drag.

    Science.gov (United States)

    Askew, Graham N

    2014-09-15

    One of the classic examples of an exaggerated sexually selected trait is the elaborate plumage that forms the train in male peafowl Pavo cristatus (peacock). Such ornaments are thought to reduce locomotor performance as a result of their weight and aerodynamic drag, but this cost is unknown. Here, the effect that the train has on take-off flight in peacocks was quantified as the sum of the rates of change of the potential and kinetic energies of the body (P(CoM)) in birds with trains and following the train's removal. There was no significant difference between P(CoM) in birds with and without a train. The train incurs drag during take-off; however, while this produces a twofold increase in parasite drag, parasite power only accounts for 0.1% of the total aerodynamic power. The train represented 6.9% of body weight and is expected to increase induced power. The absence of a detectable effect on take-off performance does not necessarily mean that there is no cost associated with possessing such ornate plumage; rather, it suggests that given the variation in take-off performance per se, the magnitude of any effect of the train has little meaningful functional relevance. © 2014. Published by The Company of Biologists Ltd.

  1. 5th Drag Reduction in Engineering Flows Meeting

    CERN Document Server

    1991-01-01

    The European Drag Reduction Meeting has been held on 15th and 16th November 1990 in London. This was the fifth of the annual European meetings on drag reduction in engineering flows. The main objective of this meeting was to discuss up-to-date results of drag reduction research carried out in Europe. The organiser has adopted the philosophy of discussing the yesterday's results rather than the last year's results. No written material has therefore been requested for the meeting. It was only after the meeting the submission of papers was requested to the participants, from which 16 papers were selected for this proceedings volume. The meeting has attracted a record number of participants with a total of 52 researchers from seven European countries, U. K. , France, Germany, the Netherlands, Italy, Switzerland and U. S. S. R. as well as from Japan, Canada and Australia. The subjects covered in this proceedings volume include riblets, LEBUs (Large Eddy Break-Up device), surface roughness, compliant surfaces and p...

  2. Coordination of multiple appendages in drag-based swimming.

    Science.gov (United States)

    Alben, Silas; Spears, Kevin; Garth, Stephen; Murphy, David; Yen, Jeannette

    2010-11-06

    Krill are aquatic crustaceans that engage in long distance migrations, either vertically in the water column or horizontally for 10 km (over 200,000 body lengths) per day. Hence efficient locomotory performance is crucial for their survival. We study the swimming kinematics of krill using a combination of experiment and analysis. We quantify the propulsor kinematics for tethered and freely swimming krill in experiments, and find kinematics that are very nearly metachronal. We then formulate a drag coefficient model which compares metachronal, synchronous and intermediate motions for a freely swimming body with two legs. With fixed leg velocity amplitude, metachronal kinematics give the highest average body speed for both linear and quadratic drag laws. The same result holds for five legs with the quadratic drag law. When metachronal kinematics is perturbed towards synchronous kinematics, an analysis shows that the velocity increase on the power stroke is outweighed by the velocity decrease on the recovery stroke. With fixed time-averaged work done by the legs, metachronal kinematics again gives the highest average body speed, although the advantage over synchronous kinematics is reduced.

  3. Airfoil Drag Reduction using Controlled Trapped Vorticity Concentrations

    Science.gov (United States)

    Desalvo, Michael; Glezer, Ari

    2017-11-01

    The aerodynamic performance of a lifting surface at low angles of attack (when the base flow is fully attached) is improved through fluidic modification of its ``apparent'' shape by superposition of near-surface trapped vorticity concentrations. In the present wind tunnel investigations, a controlled trapped vorticity concentration is formed on the pressure surface of an airfoil (NACA 4415) using a hybrid actuator comprising a passive obstruction of scale O(0.01c) and an integral synthetic jet actuator. The jet actuation frequency [Stact O(10)] is selected to be at least an order of magnitude higher than the characteristic unstable frequency of the airfoil wake, thereby decoupling the actuation from the global instabilities of the base flow. Regulation of vorticity accumulation in the vicinity of the actuator by the jet effects changes in the local pressure, leading in turn to changes in the airfoil's drag and lift. Trapped vorticity can lead to a significant reduction in drag and reduced lift (owing to the sense of the vorticity), e.g. at α =4° and Re = 6.7 .105 the drag and lift reductions are 14% and 2%, respectively. PIV measurements show the spatial variation in the distribution of vorticity concentrations and yield estimates of the corresponding changes in circulation.

  4. Role of Elasto-Inertial Turbulence in Polymer Drag Reduction

    Science.gov (United States)

    Dubief, Yves; Sid, Samir; Terrapon, Vincent

    2017-11-01

    Elasto-Inertial Turbulence (EIT) is a peculiar state of turbulence found in dilute polymer solutions flowing in parallel wall flows over a wide range of Reynolds numbers. At subcritical Reynolds numbers, appropriate boundary conditions trigger EIT, a self-sustaining cycle of energy transfers between thin sheets of stretched polymers and velocity perturbations, which translates into an increase of friction drag. For critical and supercritical Reynolds numbers, polymer additives may lead to significant drag reduction, bounded by the asymptotic state known as Maximum Drag Reduction (MDR). The present research investigates the role of EIT in the dynamics of critical and supercritical Reynolds number wall flows. Using high-fidelity direct numerical simulations of channel flows and the FENE-P model, we establish that (i) EIT is two-dimensional, (ii) the scales essential to the existence of EIT are sub-Kolmogorov, and (iii) EIT drives MDR at low and possibly moderate Reynolds number turbulent flows. These findings were validated in two different codes and using unprecedented resolutions for polymer flows. YD is grateful for the support of Binational Science Foundation. SS and VT acknowledges Fonds de la Recherche Scientifique (FNRS), MarieCurie Career Integration Grant and computing allocation from University of Liege and PRACE.

  5. Perturbed Partial Cavity Drag Reduction at High Reynolds Numbers

    Science.gov (United States)

    Makiharju, Simo; Elbing, Brian; Wiggins, Andrew; Dowling, David; Perlin, Marc; Ceccio, Steven

    2010-11-01

    Ventilated partial cavities were investigated at Reynolds numbers to 80 million. These cavities could be suitable for friction drag reduction on ocean going vessels and thereby lead to environmental and economical benefits. The test model was a 3.05 m wide by 12.9 m long flat plate, with a 0.18 m backward-facing step and a cavity-terminating beach, which had an adjustable slope, tilt and height. The step and beach trapped a ventilated partial cavity over the longitudinal mid-section of the model. Large-scale flow perturbations, mimicking the effect of ambient ocean waves were investigated. For the conditions tested a cavity could be maintained under perturbed flow conditions when the gas flux supplied was greater than the minimum required to maintain a cavity under steady conditions, with larger perturbations requiring more excess gas flux to maintain the cavity. High-speed video was used to observe the unsteady three dimensional cavity closure, the overall cavity shape, and the cavity oscillations. Cavities with friction drag reduction exceeding 95% were attained at optimal conditions. A simplified energy cost-benefit analysis of partial cavity drag reduction was also performed. The results suggest that PCDR could potentially lead to energy savings.

  6. Solar and Drag Sail Propulsion: From Theory to Mission Implementation

    Science.gov (United States)

    Johnson, Les; Alhorn, Dean; Boudreaux, Mark; Casas, Joe; Stetson, Doug; Young, Roy

    2014-01-01

    Solar and drag sail technology is entering the mainstream for space propulsion applications within NASA and around the world. Solar sails derive propulsion by reflecting sunlight from a large, mirror- like sail made of a lightweight, reflective material. The continuous sunlight pressure provides efficient primary propulsion, without the expenditure of propellant or any other consumable, allowing for very high V maneuvers and long-duration deep space exploration. Drag sails increase the aerodynamic drag on Low Earth Orbit (LEO) spacecraft, providing a lightweight and relatively inexpensive approach for end-of-life deorbit and reentry. Since NASA began investing in the technology in the late 1990's, significant progress has been made toward their demonstration and implementation in space. NASA's Marshall Space Flight Center (MSFC) managed the development and testing of two different 20-m solar sail systems and rigorously tested them under simulated space conditions in the Glenn Research Center's Space Power Facility at Plum Brook Station, Ohio. One of these systems, developed by L'Garde, Inc., is planned for flight in 2015. Called Sunjammer, the 38m sailcraft will unfurl in deep space and demonstrate solar sail propulsion and navigation as it flies to Earth-Sun L1. In the Flight Center (MSFC) managed the development and testing of two different 20-m solar sail systems and rigorously tested them under simulated space conditions in the Glenn Research Center's Space Power Facility at Plum Brook Station, Ohio. One of these systems, developed by L'Garde, Inc., is planned for flight in 2015. Called Sunjammer, the 38m sailcraft will unfurl in deep space and demonstrate solar sail propulsion and navigation as it flies to Earth-Sun L1. In the interim, NASA MSFC funded the NanoSail-D, a subscale drag sail system designed for small spacecraft applications. The NanoSail-D flew aboard the Fast Affordable Science and Technology SATellite (FASTSAT) in 2010, also developed by MSFC

  7. Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion.

    Science.gov (United States)

    Kent, David G; Li, Juan; Tanna, Hinal; Fink, Juergen; Kirschner, Kristina; Pask, Dean C; Silber, Yvonne; Hamilton, Tina L; Sneade, Rachel; Simons, Benjamin D; Green, Anthony R

    2013-01-01

    Recent descriptions of significant heterogeneity in normal stem cells and cancers have altered our understanding of tumorigenesis, emphasizing the need to understand how single stem cells are subverted to cause tumors. Human myeloproliferative neoplasms (MPNs) are thought to reflect transformation of a hematopoietic stem cell (HSC) and the majority harbor an acquired V617F mutation in the JAK2 tyrosine kinase, making them a paradigm for studying the early stages of tumor establishment and progression. The consequences of activating tyrosine kinase mutations for stem and progenitor cell behavior are unclear. In this article, we identify a distinct cellular mechanism operative in stem cells. By using conditional knock-in mice, we show that the HSC defect resulting from expression of heterozygous human JAK2V617F is both quantitative (reduced HSC numbers) and qualitative (lineage biases and reduced self-renewal per HSC). The defect is intrinsic to individual HSCs and their progeny are skewed toward proliferation and differentiation as evidenced by single cell and transplantation assays. Aged JAK2V617F show a more pronounced defect as assessed by transplantation, but mice that transform reacquire competitive self-renewal ability. Quantitative analysis of HSC-derived clones was used to model the fate choices of normal and JAK2-mutant HSCs and indicates that JAK2V617F reduces self-renewal of individual HSCs but leaves progenitor expansion intact. This conclusion is supported by paired daughter cell analyses, which indicate that JAK2-mutant HSCs more often give rise to two differentiated daughter cells. Together these data suggest that acquisition of JAK2V617F alone is insufficient for clonal expansion and disease progression and causes eventual HSC exhaustion. Moreover, our results show that clonal expansion of progenitor cells provides a window in which collaborating mutations can accumulate to drive disease progression. Characterizing the mechanism(s) of JAK2V617F

  8. Analysis of Satellite Drag Coefficient Based on Wavelet Transform

    Science.gov (United States)

    Liu, Wei; Wang, Ronglan; Liu, Siqing

    Abstract: Drag coefficient sequence was obtained by solving Tiangong1 continuous 55days GPS orbit data with different arc length. The same period solar flux f10.7 and geomagnetic index Ap ap series were high and low frequency multi-wavelet decomposition. Statistical analysis results of the layers sliding correlation between space environmental parameters and decomposition of Cd, showed that the satellite drag coefficient sequence after wavelet decomposition and the corresponding level of f10.7 Ap sequence with good lag correlation. It also verified that the Cd prediction is feasible. Prediction residuals of Cd with different regression models and different sample length were analysed. The results showed that the case was best when setting sample length 20 days and f10.7 regression model were used. It also showed that NRLMSIS-00 model's response in the region of 350km (Tiangong's altitude) and low-middle latitude (Tiangong's inclination) is excessive in ascent stage of geomagnetic activity Ap and is inadequate during fall off segment. Additionally, the low-frequency decomposition components NRLMSIS-00 model's response is appropriate in f10.7 rising segment. High frequency decomposition section, Showed NRLMSIS-00 model's response is small-scale inadequate during f10.7 ascent segment and is reverse in decline of f10.7. Finally, the potential use of a summary and outlook were listed; This method has an important reference value to improve the spacecraft orbit prediction accuracy. Key words: wavelet transform; drag coefficient; lag correlation; Tiangong1;space environment

  9. Resistive Heating and Ion Drag in Saturn's Thermosphere

    Science.gov (United States)

    Vriesema, Jess William; Koskinen, Tommi; Yelle, Roger V.

    2017-10-01

    One of the most puzzling observations of the jovian planets is that the thermospheres of Jupiter, Saturn, Uranus and Neptune are all several times hotter than solar heating can account for (Strobel and Smith 1973; Yelle and Miller 2004; Muller-Wodarg et al. 2006). On Saturn, resistive heating appears sufficient to explain these temperatures in auroral regions, but the particular mechanism(s) responsible for heating the lower latitudes remains unclear. The most commonly proposed heating mechanisms are breaking gravity waves and auroral heating at the poles followed by redistribution of energy to mid-and low latitudes. Both of these energy sources are potentially important but also come with significant problems. Wave heating would have to be continuous and global to produce consistently elevated temperatures and the strong Coriolis forces coupled with polar ion drag appear to hinder redistribution of auroral energy (see Strobel et al. 2016 for review). Here we explore an alternative: wind-driven electrodynamics that can alter circulation and produce substantial heating outside of the auroral region. Smith (2013) showed this in-situ mechanism to be potentially significant in Jupiter’s thermosphere. We present new results from an axisymmetric, steady-state model that calculates resistive (Joule) heating rates through rigorous solutions of the electrodynamic equations for the coupled neutral atmosphere and ionosphere of Saturn. At present, we assume a dipole magnetic field and neglect any contributions from the magnetosphere. We use ion mixing ratios from the model of Kim et al. (2014) and the observed temperature-pressure profile from Koskinen et al. (2015) to calculate the generalized conductivity tensor as described by Koskinen et al. (2014). We calculate the current density under the assumption that it has no divergence and use it to calculate the resistive heating rates and ion drag. Our results suggest that resistive heating and ion drag at low latitudes likely

  10. Satellite Orbit Under Influence of a Drag - Analytical Approach

    Science.gov (United States)

    Martinović, M. M.; Šegan, S. D.

    2017-12-01

    The report studies some changes in orbital elements of the artificial satellites of Earth under influence of atmospheric drag. In order to develop possibilities of applying the results in many future cases, an analytical interpretation of the orbital element perturbations is given via useful, but very long expressions. The development is based on the TD88 air density model, recently upgraded with some additional terms. Some expressions and formulae were developed by the computer algebra system Mathematica and tested in some hypothetical cases. The results have good agreement with iterative (numerical) approach.

  11. Air Flows in Gravity Sewers - Determination of Wastewater Drag Coefficient

    DEFF Research Database (Denmark)

    Bentzen, Thomas Ruby; Østertoft, Kristian; Vollertsen, Jes

    2016-01-01

    Several experiments have been conducted in order to improve the understanding of the wastewater drag and the wall frictional force acting on the headspace air in gravity sewers. The aim of the study is to improve the data basis for a numerical model of natural sewer ventilation. The results...... of the study shows that by integrating the top/side wall shear stresses the log-law models for the air velocity distribution along the unwetted perimeter resulted in a good agreement with the friction forces calculated by use of the Colebrook-White formula for hydraulic smooth pipes. Secondly, the water...

  12. Drag Reduction trough Special paints Coated on the hull

    OpenAIRE

    Izaguirre Alza, Patricia; Pérez Rojas, Luis; Núñez Basáñez, José Fernando

    2010-01-01

    The economic recession, the environmental impact as well as the continuous fossil fuel consumption encourage actions that focus on saving energy. In the vessels sector, one of the main objectives has always been to reach a hydro-dynamically optimum hull which gave the desired speed with minimum power. Hydrodynamic drag is basically divided into two parts: a) the friction between the water and the hull, and b) the wave generation due to the free-surface air-water. Presented in this paper...

  13. Drag prediction for blades at high angle of attack using CFD

    DEFF Research Database (Denmark)

    Sørensen, Niels N.; Michelsen, J.A.

    2004-01-01

    In the present paper it is first demonstrated that state of the art 3D CFD codes are. capable of predicting the correct dependency of the integrated drag of a flat plate placed perpendicular to the flow. This is in strong contrast to previous 2D investigations of infinite plates, where computations...... are known to severely overpredict drag. We then demonstrate that the computed drag distribution along the plate span deviate from the general expectation of 2D behavior at the central part of the plate, an important finding in connection with the theoretical estimation of drag behavior on wind turbine...... blades. The computations additionally indicate that a tip effect is present that produces increased drag near the end of the plate, which is opposite of the assumptions generally used in drag estimation for blades. Following this several wind turbine blades are analyzed, ranging from older blades...

  14. Nonuniform charging effects on ion drag force in drifting dusty plasmas

    International Nuclear Information System (INIS)

    Chang, Dong-Man; Chang, Won-Seok; Jung, Young-Dae

    2006-01-01

    The nonuniform polarization charging effects on the ion drag force are investigated in drifting dusty plasmas. The ion drag force due to the ion-dust grain interaction is obtained as a function of the dust charge, ion charge, plasma temperature, Mach number, Debye length, and collision energy. The result shows that the nonuniform charging effects enhance the momentum transfer cross section as well as the ion drag force. It is found that the momentum transfer cross section and the ion drag force including nonuniform polarization charging effects increase with increasing the Mach number and also the ion drag force increases with increasing the temperature. In addition, it is found that the ion drag force is slightly decreasing with an increase of the Debye length

  15. Frictional Magneto-Coulomb Drag in Graphene Double-Layer Heterostructures.

    Science.gov (United States)

    Liu, Xiaomeng; Wang, Lei; Fong, Kin Chung; Gao, Yuanda; Maher, Patrick; Watanabe, Kenji; Taniguchi, Takashi; Hone, James; Dean, Cory; Kim, Philip

    2017-08-04

    Coulomb interaction between two closely spaced parallel layers of conductors can generate the frictional drag effect by interlayer Coulomb scattering. Employing graphene double layers separated by few-layer hexagonal boron nitride, we investigate density tunable magneto- and Hall drag under strong magnetic fields. The observed large magnetodrag and Hall-drag signals can be related with Laudau level filling status of the drive and drag layers. We find that the sign and magnitude of the drag resistivity tensor can be quantitatively correlated to the variation of magnetoresistivity tensors in the drive and drag layers, confirming a theoretical formula for magnetodrag in the quantum Hall regime. The observed weak temperature dependence and ∼B^{2} dependence of the magnetodrag are qualitatively explained by Coulomb scattering phase-space argument.

  16. Aerodynamic Efficiency Analysis on Modified Drag Generator of Tanker-Ship Using Symmetrical Airfoil

    Science.gov (United States)

    Moranova, Starida; Rahmat Hadiyatul A., S. T.; Indra Permana S., S. T.

    2018-04-01

    Time reduction of tanker ship spent in the sea should be applied for solving problems occured in oil and gas distribution, such as the unpunctuality of the distribution and oil spilling. The aerodynamic design for some parts that considered as drag generators is presumed to be one of the solution, utilizing our demand of the increasing speed. This paper suggests two examples of the more-aerodynamic design of a part in the tanker that is considered a drag generator, and reports the value of drag generated from the basic and the suggested aerodynamic designs. The new designs are made by adding the NACA airfoil to the cross section of the drag generator. The scenario is assumed with a 39 km/hour speed of tanker, neglecting the hydrodynamic effects occured in the tanker by cutting it at the waterline which separated the drag between air and water. The results of produced drag in each design are calculated by Computational Fluid Dynamic method.

  17. Ad/dressing the nation: drag and authenticity in post-apartheid South Africa.

    Science.gov (United States)

    Spruill, Jennifer

    2004-01-01

    This paper examines a style of drag in South Africa that features "traditional African" clothing. In a region in which homosexuality is denigrated as a colonial, European import and "unAfrican," the meaning of "traditional drag" is deeply inflected by the question of cultural authenticity. This dragging practice fits within a distinctly post-colonial production of tradition and its self-conscious display--in the form of attire--of a decidedly "gay" one. Traditional drag also responds to ongoing politics within and between lesbian and gay communities about racial "representivity" and "transformation." The paper focuses on displays of traditional drag at Johannesburg's Gay and Lesbian Pride Parade but also explores the complex politics of publicity and address suggested by varying contexts in which traditional dress and drag are mobilized.

  18. Hypersonic wave drag reduction performance of cylinders with repetitive laser energy depositions

    International Nuclear Information System (INIS)

    Fang, J; Hong, Y J; Li, Q; Huang, H

    2011-01-01

    It has been widely research that wave drag reduction on hypersonic vehicle by laser energy depositions. Using laser energy to reduce wave drag can improve vehicle performance. A second order accurate scheme based on finite-difference method and domain decomposition of structural grid is used to compute the drag performance of cylinders in a hypersonic flow of Mach number 2 at altitude of 15km with repetitive energy depositions. The effects of frequency on drag reduction are studied. The calculated results show: the recirculation zone is generated due to the interaction between bow shock over the cylinder and blast wave produced by energy deposition, and a virtual spike which is supported by an axis-symmetric recirculation, is formed in front of the cylinder. By increasing the repetitive frequency, the drag is reduced and the oscillation of the drag is decreased; however, the energy efficiency decreases by increasing the frequency.

  19. Synthetic Effect of Vivid Shark Skin and Polymer Additive on Drag Reduction Reinforcement

    Directory of Open Access Journals (Sweden)

    Huawei Chen

    2014-06-01

    Full Text Available Natural shark skin has a well-demonstrated drag reduction function, which is mainly owing to its microscopic structure and mucus on the body surface. In order to improve drag reduction, it is necessary to integrate microscopic drag reduction structure and drag reduction agent. In this study, two hybrid approaches to synthetically combine vivid shark skin and polymer additive, namely, long-chain grafting and controllable polymer diffusion, were proposed and attempted to mimic such hierarchical topography of shark skin without waste of polymer additive. Grafting mechanism and optimization of diffusion port were investigated to improve the efficiency of the polymer additive. Superior drag reduction effects were validated, and the combined effect was also clarified through comparison between drag reduction experiments.

  20. Numerical Study of Natural Supercavitation Influenced by Rheological Properties of Turbulent Drag-Reducing Additives

    Directory of Open Access Journals (Sweden)

    Chen-Xing Jiang

    2014-08-01

    Full Text Available Natural supercavitations in water and turbulent drag-reducing solution were numerically simulated using unsteady Reynolds averaged Navier-Stokes (RANS scheme with mixture-multiphase model. The Cross viscosity equation was adopted to represent the fluid property of aqueous solution of drag-reducing additives. The characteristics of natural supercavity configuration and overall resistance of the navigating body were presented, respectively. The numerical simulation results indicated that, at the same cavitation number, the length and diameter of supercavity in drag-reducing solution are larger than those in water, and the drag coefficient of navigating body in solution is smaller than that in water; the surface tension plays an important role in incepting and maintaining the cavity. Turbulent drag-reducing additives have the potential in enhancement of supercavitation, drag reduction, and decrease of turbulent vortex structures. Numerical simulation results are consistent with the available experimental data.

  1. CFD Prediction of Airfoil Drag in Viscous Flow Using the Entropy Generation Method

    Directory of Open Access Journals (Sweden)

    Wei Wang

    2018-01-01

    Full Text Available A new aerodynamic force of drag prediction approach was developed to compute the airfoil drag via entropy generation rate in the flow field. According to the momentum balance, entropy generation and its relationship to drag were derived for viscous flow. Model equations for the calculation of the local entropy generation in turbulent flows were presented by extending the RANS procedure to the entropy balance equation. The accuracy of algorithm and programs was assessed by simulating the pressure coefficient distribution and dragging coefficient of different airfoils under different Reynolds number at different attack angle. Numerical data shows that the total entropy generation rate in the flow field and the drag coefficient of the airfoil can be related by linear equation, which indicates that the total drag could be resolved into entropy generation based on its physical mechanism of energy loss.

  2. The Role of Rough Topography in Mediating Impacts of Bottom Drag in Eddying Ocean Circulation Models.

    Science.gov (United States)

    Trossman, David S; Arbic, Brian K; Straub, David N; Richman, James G; Chassignet, Eric P; Wallcraft, Alan J; Xu, Xiaobiao

    2017-08-01

    Motivated by the substantial sensitivity of eddies in two-layer quasi-geostrophic (QG) turbulence models to the strength of bottom drag, this study explores the sensitivity of eddies in more realistic ocean general circulation model (OGCM) simulations to bottom drag strength. The OGCM results are interpreted using previous results from horizontally homogeneous, two-layer, flat-bottom, f-plane, doubly periodic QG turbulence simulations and new results from two-layer β -plane QG turbulence simulations run in a basin geometry with both flat and rough bottoms. Baroclinicity in all of the simulations varies greatly with drag strength, with weak drag corresponding to more barotropic flow and strong drag corresponding to more baroclinic flow. The sensitivity of the baroclinicity in the QG basin simulations to bottom drag is considerably reduced, however, when rough topography is used in lieu of a flat bottom. Rough topography reduces the sensitivity of the eddy kinetic energy amplitude and horizontal length scales in the QG basin simulations to bottom drag to an even greater degree. The OGCM simulation behavior is qualitatively similar to that in the QG rough bottom basin simulations in that baroclinicity is more sensitive to bottom drag strength than are eddy amplitudes or horizontal length scales. Rough topography therefore appears to mediate the sensitivity of eddies in models to the strength of bottom drag. The sensitivity of eddies to parameterized topographic internal lee wave drag, which has recently been introduced into some OGCMs, is also briefly discussed. Wave drag acts like a strong bottom drag in that it increases the baroclinicity of the flow, without strongly affecting eddy horizontal length scales.

  3. On the influence of drag effect on acoustic modes in two-condensate relativistic superfluid systems

    International Nuclear Information System (INIS)

    Vil'chinskij, S.I.

    1999-01-01

    Equations of velocities of acoustic excitations in a relativistic two-condensate superfluid system are derived with due account of reciprocal drag of superfluid motion (drag effect). The influence of the drag effect on acoustic modes in the system is considered. It is shown that the effect does not influence the nature of acoustic excitation oscillations but produces changes in the velocities of the second, third and fourth sounds

  4. Drag Moderation by the Melting of an Ice Surface in Contact with Water

    KAUST Repository

    Vakarelski, Ivan Uriev

    2015-07-24

    We report measurements of the effects of a melting ice surface on the hydrodynamic drag of ice-shell-metal-core spheres free falling in water at a Reynolds of number Re∼2×104–3×105 and demonstrate that the melting surface induces the early onset of the drag crisis, thus reducing the hydrodynamic drag by more than 50%. Direct visualization of the flow pattern demonstrates the key role of surface melting. Our observations support the hypothesis that the drag reduction is due to the disturbance of the viscous boundary layer by the mass transfer from the melting ice surface.

  5. Experimental and numerical investigation of low-drag intervals in turbulent boundary layer

    Science.gov (United States)

    Park, Jae Sung; Ryu, Sangjin; Lee, Jin

    2017-11-01

    It has been widely investigated that there is a substantial intermittency between high and low drag states in wall-bounded shear flows. Recent experimental and computational studies in a turbulent channel flow have identified low-drag time intervals based on wall shear stress measurements. These intervals are a weak turbulence state characterized by low-speed streaks and weak streamwise vortices. In this study, the spatiotemporal dynamics of low-drag intervals in a turbulent boundary layer is investigated using experiments and simulations. The low-drag intervals are monitored based on the wall shear stress measurement. We show that near the wall conditionally-sampled mean velocity profiles during low-drag intervals closely approach that of a low-drag nonlinear traveling wave solution as well as that of the so-called maximum drag reduction asymptote. This observation is consistent with the channel flow studies. Interestingly, the large spatial stretching of the streak is very evident in the wall-normal direction during low-drag intervals. Lastly, a possible connection between the mean velocity profile during the low-drag intervals and the Blasius profile will be discussed. This work was supported by startup funds from the University of Nebraska-Lincoln.

  6. Drag Moderation by the Melting of an Ice Surface in Contact with Water

    KAUST Repository

    Vakarelski, Ivan Uriev; Chan, Derek Y.  C.; Thoroddsen, Sigurdur T

    2015-01-01

    We report measurements of the effects of a melting ice surface on the hydrodynamic drag of ice-shell-metal-core spheres free falling in water at a Reynolds of number Re∼2×104–3×105 and demonstrate that the melting surface induces the early onset of the drag crisis, thus reducing the hydrodynamic drag by more than 50%. Direct visualization of the flow pattern demonstrates the key role of surface melting. Our observations support the hypothesis that the drag reduction is due to the disturbance of the viscous boundary layer by the mass transfer from the melting ice surface.

  7. Modelling of Structural Loads in Drag Augmented Space Debris Removal Concepts

    DEFF Research Database (Denmark)

    Kristensen, Anders Schmidt; Nikolajsen, Jan Ánike; Lauridsen, Peter Riddersholm

    2017-01-01

    A Self-deployable Deorbiting Space Structure (SDSS) is used for drag augmented space debris removal. A highly flexible frame allows for a folding of the structure by bifurcation. This research models the structural loads during the deployment and unfolding of the drag sail in Low Earth Orbit (LEO......). The Spacecraft travels with 7.8 km/s at deployment. As the drag sail unfolds instantaneously the structure must withstand the loads from the unfolding and the drag. Thermal loads are included in the FEA as the temperature varies from -80°C to +80°C during deorbit. The results are used to verify the structural...

  8. Concentrated energy addition for active drag reduction in hypersonic flow regime

    Science.gov (United States)

    Ashwin Ganesh, M.; John, Bibin

    2018-01-01

    Numerical optimization of hypersonic drag reduction technique based on concentrated energy addition is presented in this study. A reduction in wave drag is realized through concentrated energy addition in the hypersonic flowfield upstream of the blunt body. For the exhaustive optimization presented in this study, an in-house high precision inviscid flow solver has been developed. Studies focused on the identification of "optimum energy addition location" have revealed the existence of multiple minimum drag points. The wave drag coefficient is observed to drop from 0.85 to 0.45 when 50 Watts of energy is added to an energy bubble of 1 mm radius located at 74.7 mm upstream of the stagnation point. A direct proportionality has been identified between energy bubble size and wave drag coefficient. Dependence of drag coefficient on the upstream added energy magnitude is also revealed. Of the observed multiple minimum drag points, the energy deposition point (EDP) that offers minimum wave drag just after a sharp drop in drag is proposed as the most optimum energy addition location.

  9. Monte Carlo calculations of the free-molecule drag on chains of uniform spheres

    International Nuclear Information System (INIS)

    Dahneke, B.; Chan, P.

    1980-01-01

    Monte Carlo calculations of the free-molecule drag on straight chains of uniform spheres are presented. The drag on a long chain is expressed in terms of the drag on a basic chain unit (two hemispheres touching at their poles) multiplied by the number of spheres in the chain. Since there is no interaction between the basic chain units, it is argued that the results also apply as a good approximation to the drag on kinked and branched chains covering a broad range of geometries. Experimental data are cited which support this claim

  10. Experimental Investigation of the Fresnel Drag Effect in RF Coaxial Cables

    Directory of Open Access Journals (Sweden)

    Cahill R. T.

    2011-01-01

    Full Text Available An experiment that confirms the Fresnel drag formalism in RF coaxial cables is re- ported. The Fresnel ‘drag’ in bulk dielectrics and in optical fibers has previously been well established. An explanation for this formalism is given, and it is shown that there is no actual drag phenomenon, rather that the Fresnel drag effect is merely the conse- quence of a simplified description of EM scattering within a dielectric in motion wrt the dynamical 3-space. The Fresnel drag effect plays a critical role in the design of various light-speed anisotropy detectors.

  11. Incorporating modelled subglacial hydrology into inversions for basal drag

    Directory of Open Access Journals (Sweden)

    C. P. Koziol

    2017-12-01

    Full Text Available A key challenge in modelling coupled ice-flow–subglacial hydrology is initializing the state and parameters of the system. We address this problem by presenting a workflow for initializing these values at the start of a summer melt season. The workflow depends on running a subglacial hydrology model for the winter season, when the system is not forced by meltwater inputs, and ice velocities can be assumed constant. Key parameters of the winter run of the subglacial hydrology model are determined from an initial inversion for basal drag using a linear sliding law. The state of the subglacial hydrology model at the end of winter is incorporated into an inversion of basal drag using a non-linear sliding law which is a function of water pressure. We demonstrate this procedure in the Russell Glacier area and compare the output of the linear sliding law with two non-linear sliding laws. Additionally, we compare the modelled winter hydrological state to radar observations and find that it is in line with summer rather than winter observations.

  12. Bluff-body drag reduction using a deflector

    Energy Technology Data Exchange (ETDEWEB)

    Fourrie, Gregoire; Keirsbulck, Laurent; Labraga, Larbi [Univ Lille Nord de France, Lille (France); UVHC, TEMPO, Valenciennes (France); Gillieron, Patrick [Fluid Mechanics and Aerodynamics, Renault Group, Research Division, Guyancourt (France)

    2011-02-15

    A passive flow control on a generic car model was experimentally studied. This control consists of a deflector placed on the upper edge of the model rear window. The study was carried out in a wind tunnel at Reynolds numbers based on the model height of 3.1 x 10{sup 5} and 7.7 x 10{sup 5}. The flow was investigated via standard and stereoscopic particle image velocimetry, Kiel pressure probes and surface flow visualization. The aerodynamic drag was measured using an external balance and calculated using a wake survey method. Drag reductions up to 9% were obtained depending on the deflector angle. The deflector increases the separated region on the rear window. The results show that when this separated region is wide enough, it disrupts the development of the counter-rotating longitudinal vortices appearing on the lateral edges of the rear window. The current study suggests that flow control on such geometries should consider all the flow structures that contribute to the model wake flow. (orig.)

  13. Bluff-body drag reduction using a deflector

    Science.gov (United States)

    Fourrié, Grégoire; Keirsbulck, Laurent; Labraga, Larbi; Gilliéron, Patrick

    2011-02-01

    A passive flow control on a generic car model was experimentally studied. This control consists of a deflector placed on the upper edge of the model rear window. The study was carried out in a wind tunnel at Reynolds numbers based on the model height of 3.1 × 105 and 7.7 × 105. The flow was investigated via standard and stereoscopic particle image velocimetry, Kiel pressure probes and surface flow visualization. The aerodynamic drag was measured using an external balance and calculated using a wake survey method. Drag reductions up to 9% were obtained depending on the deflector angle. The deflector increases the separated region on the rear window. The results show that when this separated region is wide enough, it disrupts the development of the counter-rotating longitudinal vortices appearing on the lateral edges of the rear window. The current study suggests that flow control on such geometries should consider all the flow structures that contribute to the model wake flow.

  14. CAPTURE OF PLANETESIMALS BY GAS DRAG FROM CIRCUMPLANETARY DISKS

    International Nuclear Information System (INIS)

    Fujita, Tetsuya; Ohtsuki, Keiji; Suetsugu, Ryo; Tanigawa, Takayuki

    2013-01-01

    Growing giant planets have circumplanetary disks around them in the late stage of their formation if their mass is sufficiently large. We examine capture of relatively large planetesimals that are decoupled from the gas inflow, due to gas drag from a circumplanetary disk of a growing giant planet. Assuming that the structure of the circumplanetary disk is axisymmetric, and solving the three-body problem including gas drag, we perform analytic and numerical calculations for capture of planetesimals. When planetesimal random velocity is small, planetesimals approaching in the retrograde direction are more easily captured, owing to their larger velocity relative to the gas. Planetesimals with large orbital inclinations interact with the disk for a short period of time and show lower capture rates. The effect of ablation on capture rates seems insignificant, although mass loss due to ablation would be significant in the case of high random velocity. We also examine the effect of non-uniform radial distribution of planetesimals in the protoplanetary disk due to gap opening by the planet. When the random velocity of planetesimals is small, the planetesimal capture rate decreases rapidly as the half width of the gap in the planetesimal disk increases from two planetary Hill radii to three planetary Hill radii; planetesimals with low random velocities cannot approach the planet in the case of a sufficiently wide gap. Our results show that the radial distribution and random velocity of planetesimals in the protoplanetary disk are essentially important for the understanding of capture of planetesimals by circumplanetary disks

  15. Drag reduction in silica nanochannels induced by graphitic wall coatings

    Science.gov (United States)

    Wagemann, Enrique; Walther, J. H.; Zambrano, Harvey A.

    2017-11-01

    Transport of water in hydrophilic nanopores is of significant technological and scientific interest. Water flow through hydrophilic nanochannels is known to experience enormous hydraulic resistance. Therefore, drag reduction is essential for the development of highly efficient nanofluidic devices. In this work, we propose the use of graphitic materials as wall coatings in hydrophilic silica nanopores. Specifically, by conducting atomistic simulations, we investigate the flow inside slit and cylindrical silica channels with walls coated with graphene (GE) layers and carbon nanotubes (CNTs), respectively. We develop realistic force fields to simulate the systems of interest and systematically, compare flow rates in coated and uncoated nanochannels under different pressure gradients. Moreover, we assess the effect that GE and CNT translucencies to wettability have on water hydrodynamics in the nanochannels. The influence of channel size is investigated by systematically varying channel heights and nanopore diameters. In particular, we present the computed water density and velocity profiles, volumetric flow rates, slip lengths and flow enhancements, to clearly demonstrate the drag reduction capabilities of graphitic wall coatings. We wish to thank partial funding from CRHIAM Conicyt/ Fondap Project 15130015 and computational support from DTU and NLHPC (Chile).

  16. Studies of drag on the nanocomposite superhydrophobic surfaces

    Science.gov (United States)

    Brassard, Jean-Denis; Sarkar, D. K.; Perron, Jean

    2015-01-01

    The nanocomposite thin films of stearic acid (SA)-functionalized ZnO nanoparticles incorporated in epoxy polymer matrix have been achieved. The X-ray diffraction (XRD) studies show the formation of zinc stearate on ZnO nanoparticles as the confirmation of SA-functionalization of ZnO nanoparticles in the thin films. Morphological analyses reveal the presence of micro-holes with the presence of irregular nanoparticles. The measured root mean square (rms) roughness of the thin film is found to be 12 ± 1 μm with the adhesion of 5B on both glass and aluminum substrates. The wetting property shows that the surface of the film is superhydrophobic with the contact angle of water of 156 ± 4° having contact angle hysteresis (CAH) of 4 ± 2°. The average terminal velocity in the water of the as-received glass spheres and superhydrophobic spheres were found to be 0.66 ± 0.01 m/s and 0.72 ± 0.01 m/s respectively. Consequently, the calculated average coefficients of the surface drag of the as-received glass sphere and superhydrophobic glass sphere were 2.30 ± 0.01 and 1.93 ± 0.03, respectively. Hence, the drag reduction on the surface of superhydrophobic glass sphere is found to be approximately 16% lower than as-received glass sphere.

  17. Vertical, radial and drag force analysis of superconducting magnetic bearings

    International Nuclear Information System (INIS)

    Cansiz, Ahmet

    2009-01-01

    The behavior of the force between a permanent magnet (PM) and a high temperature superconductor (HTS) was tested with the frozen-image model based on flux pinning. It was found that the associated dipole moment assumptions of the method of the frozen image underestimate the force somewhat; thus a quadrupole moment analysis is proposed. The radial and drag forces associated with the rotation of the PM levitated above the HTS were measured by using a force transducer and by means of a cantilevered beam technique. The radial force was found not to be dependent on the radial direction, and the least radial force was found to be periodic with an angular displacement during the slow rotation of the PM relative to the HTS. The periodicity behavior of the force is attributed to the geometric eccentricity from the magnetization distribution of the PM and HTS. The drag force associated with the torsional stiffness of the levitated PM during the low and high rotational speeds was incorporated with the data from the literature.

  18. Drag reduction of a rapid vehicle in supercavitating flow

    Directory of Open Access Journals (Sweden)

    D. Yang

    2017-01-01

    Full Text Available Supercavitation is one of the most attractive technologies to achieve high speed for underwater vehicles. However, the multiphase flow with high-speed around the supercavitating vehicle (SCV is difficult to simulate accurately. In this paper, we use modified the turbulent viscosity formula in the Standard K-Epsilon (SKE turbulent model to simulate the supercavitating flow. The numerical results of flow over several typical cavitators are in agreement with the experimental data and theoretical prediction. In the last part, a flying SCV was studied by unsteady numerical simulation. The selected computation setup corresponds to an outdoor supercavitating experiment. Only very limited experimental data was recorded due to the difficulties under the circumstance of high-speed underwater condition. However, the numerical simulation recovers the whole scenario, the results are qualitatively reasonable by comparing to the experimental observations. The drag reduction capacity of supercavitation is evaluated by comparing with a moving vehicle launching at the same speed but without supercavitation. The results show that the supercavitation reduces the drag of the vehicle dramatically.

  19. Do spinors give rise to a frame-dragging effect?

    International Nuclear Information System (INIS)

    Randono, Andrew

    2010-01-01

    We investigate the effect of the intrinsic spin of a fundamental spinor field on the surrounding spacetime geometry. We show that despite the lack of a rotating stress-energy source (and despite claims to the contrary) the intrinsic spin of a spin-half fermion gives rise to a frame-dragging effect analogous to that of orbital angular momentum, even in Einstein-Hilbert gravity where torsion is constrained to be zero. This resolves a paradox regarding the counter-force needed to restore Newton's third law in the well-known spin-orbit interaction. In addition, the frame-dragging effect gives rise to a long-range gravitationally mediated spin-spin dipole interaction coupling the internal spins of two sources. We argue that despite the weakness of the interaction, the spin-spin interaction will dominate over the ordinary inverse square Newtonian interaction in any process of sufficiently high energy for quantum field theoretical effects to be non-negligible.

  20. Gliding flight: drag and torque of a hawk and a falcon with straight and turned heads, and a lower value for the parasite drag coefficient.

    Science.gov (United States)

    Tucker, V A

    2000-12-01

    Raptors - falcons, hawks and eagles in this study - such as peregrine falcons (Falco peregrinus) that attack distant prey from high-speed dives face a paradox. Anatomical and behavioral measurements show that raptors of many species must turn their heads approximately 40 degrees to one side to see the prey straight ahead with maximum visual acuity, yet turning the head would presumably slow their diving speed by increasing aerodynamic drag. This paper investigates the aerodynamic drag part of this paradox by measuring the drag and torque on wingless model bodies of a peregrine falcon and a red-tailed hawk (Buteo jamaicensis) with straight and turned heads in a wind tunnel at a speed of 11.7 m s(-)(1). With a turned head, drag increased more than 50 %, and torque developed that tended to yaw the model towards the direction in which the head pointed. Mathematical models for the drag required to prevent yawing showed that the total drag could plausibly more than double with head-turning. Thus, the presumption about increased drag in the paradox is correct. The relationships between drag, head angle and torque developed here are prerequisites to the explanation of how a raptor could avoid the paradox by holding its head straight and flying along a spiral path that keeps its line of sight for maximum acuity pointed sideways at the prey. Although the spiral path to the prey is longer than the straight path, the raptor's higher speed can theoretically compensate for the difference in distances; and wild peregrines do indeed approach prey by flying along curved paths that resemble spirals. In addition to providing data that explain the paradox, this paper reports the lowest drag coefficients yet measured for raptor bodies (0.11 for the peregrine and 0.12 for the red-tailed hawk) when the body models with straight heads were set to pitch and yaw angles for minimum drag. These values are markedly lower than value of the parasite drag coefficient (C(D,par)) of 0.18 previously

  1. Centralized mouse repositories.

    Science.gov (United States)

    Donahue, Leah Rae; Hrabe de Angelis, Martin; Hagn, Michael; Franklin, Craig; Lloyd, K C Kent; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Hörlein, Andreas; Davisson, Muriel T

    2012-10-01

    Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring the ongoing availability of these mouse strains preserves the investment made in creating and characterizing them and creates a global resource of enormous value. The establishment of centralized mouse repositories around the world for distributing and archiving these resources has provided critical access to and preservation of these strains. This article describes the common and specialized activities provided by major mouse repositories around the world.

  2. Surface pressure drag for hydrostatic two-layer flow over axisymmetric mountains

    Energy Technology Data Exchange (ETDEWEB)

    Leutbecher, M.

    2000-07-01

    The effect of partial reflections on surface pressure drag is investigated for hydrostatic gravity waves in two-layer flow with piecewise constant buoyancy frequency. The variation of normalized surface pressure drag with interface height is analyzed for axisymmetric mountains. The results are compared with the familiar solution for infinitely long ridges. The drag for the two-layer flow is normalized with the drag of one-layer flow, which has the buoyancy frequency of the lower layer. An analytical expression for the normalized drag of axisymmetric mountains is derived from linear theory of steady flow. Additionally, two-layer flow over finite-height axisymmetric mountains is simulated numerically for flow with higher stability in the upper layer. The temporal evolution of the surface pressure drag is examined in a series of experiments with different interface and mountain heights. The focus is on the linear regime and the nonlinear regime of nonbreaking gravity waves. The dispersion of gravity waves in flow over isolated mountains prevents that the entire wave spectrum is in resonance at the same interface height, which is the case in hydrostatic flow over infinitely long ridges. In consequence, the oscillation of the normalized drag with interface height is smaller for axisymmetric mountains than for infinitely long ridges. However, even for a reflection coefficient as low as 1/3 the drag of an axisymmetric mountain can be amplified by 50% and reduced by 40%. The nonlinear drag becomes steady in the numerical experiments in which no wave breaking occurs. The steady state nonlinear drag agrees quite well with the prediction of linear theory if the linear drag is computed for a slightly lowered interface. (orig.)

  3. UO2 Grain Growth: Developing Phase Field Models for Pore Dragging, Solute Dragging and Anisotropic Grain Boundary Energies

    International Nuclear Information System (INIS)

    Ahmed, K.; Tonks, M.; Zhang, Y.; Biner, B.

    2016-01-01

    A detailed phase field model for the effect of pore drag on grain growth kinetics was implemented in MARMOT. The model takes into consideration both the curvature-driven grain boundary motion and pore migration by surface diffusion. As such, the model accounts for the interaction between pore and grain boundary kinetics, which tends to retard the grain growth process. Our 2D and 3D simulations demonstrate that the model capture all possible pore-grain boundary interactions proposed in theoretical models. For high enough surface mobility, the pores move along with the migrating boundary as a quasi-rigid-body, albeit hindering its migration rate compared to the pore-free case. For less mobile pores, the migrating boundary can separate from the pores. For the pore-controlled grain growth kinetics, the model predicts a strong dependence of the growth rate on the number of pores, pore size, and surface diffusivity in agreement with theroretical models. An evolution equation for the grain size that includes these parameters was derived and showed to agree well with numerical solution. It shows a smooth transition from boundary-controlled kinetics to pore-controlled kinetics as the surface diffusivity decreases or the number of pores or their size increases. This equation can be utilized in BISON to give accurate estimate for the grain size evolution. This will be accomplished in the near future. The effect of solute drag and anisotropy of grain boundary on grain growth will be investigated in future studies.

  4. Studies of drag on the nanocomposite superhydrophobic surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Brassard, Jean-Denis [Anti-icing Materials International Laboratory (AMIL), Université du Québec à Chicoutimi, 555 Boulevard de l‘Université, Chicoutimi, Québec, Canada G7H 2B1 (Canada); Centre Universitaire de Recherche sur l’Aluminium (CURAL), Université du Québec à Chicoutimi, 555 Boulevard de l‘Université, Chicoutimi, Québec, Canada G7H 2B1 (Canada); Sarkar, D.K., E-mail: dsarkar@uqac.ca [Centre Universitaire de Recherche sur l’Aluminium (CURAL), Université du Québec à Chicoutimi, 555 Boulevard de l‘Université, Chicoutimi, Québec, Canada G7H 2B1 (Canada); Perron, Jean [Anti-icing Materials International Laboratory (AMIL), Université du Québec à Chicoutimi, 555 Boulevard de l‘Université, Chicoutimi, Québec, Canada G7H 2B1 (Canada)

    2015-01-01

    Graphical abstract: - Highlights: • The nanocomposite thin films of stearic acid (SA)-functionalized ZnO nanoparticles incorporated in epoxy polymer matrix have been achieved. • SA-functionalization of ZnO nanoparticles in the thin films was confirmed by XRD and FTIR. • The measured rms roughness of the thin film is found to be 12 ± 1 μm with the adhesion of 5B on glass. • The wetting property shows that the surface of the film is superhydrophobic with the CA of 156 ± 4° and CAH of 4 ± 2°. • The drag reduction on the surface of superhydrophobic glass sphere is 16% lower than as-received glass sphere. - Abstract: The nanocomposite thin films of stearic acid (SA)-functionalized ZnO nanoparticles incorporated in epoxy polymer matrix have been achieved. The X-ray diffraction (XRD) studies show the formation of zinc stearate on ZnO nanoparticles as the confirmation of SA-functionalization of ZnO nanoparticles in the thin films. Morphological analyses reveal the presence of micro-holes with the presence of irregular nanoparticles. The measured root mean square (rms) roughness of the thin film is found to be 12 ± 1 μm with the adhesion of 5B on both glass and aluminum substrates. The wetting property shows that the surface of the film is superhydrophobic with the contact angle of water of 156 ± 4° having contact angle hysteresis (CAH) of 4 ± 2°. The average terminal velocity in the water of the as-received glass spheres and superhydrophobic spheres were found to be 0.66 ± 0.01 m/s and 0.72 ± 0.01 m/s respectively. Consequently, the calculated average coefficients of the surface drag of the as-received glass sphere and superhydrophobic glass sphere were 2.30 ± 0.01 and 1.93 ± 0.03, respectively. Hence, the drag reduction on the surface of superhydrophobic glass sphere is found to be approximately 16% lower than as-received glass sphere.

  5. Studies of drag on the nanocomposite superhydrophobic surfaces

    International Nuclear Information System (INIS)

    Brassard, Jean-Denis; Sarkar, D.K.; Perron, Jean

    2015-01-01

    Graphical abstract: - Highlights: • The nanocomposite thin films of stearic acid (SA)-functionalized ZnO nanoparticles incorporated in epoxy polymer matrix have been achieved. • SA-functionalization of ZnO nanoparticles in the thin films was confirmed by XRD and FTIR. • The measured rms roughness of the thin film is found to be 12 ± 1 μm with the adhesion of 5B on glass. • The wetting property shows that the surface of the film is superhydrophobic with the CA of 156 ± 4° and CAH of 4 ± 2°. • The drag reduction on the surface of superhydrophobic glass sphere is 16% lower than as-received glass sphere. - Abstract: The nanocomposite thin films of stearic acid (SA)-functionalized ZnO nanoparticles incorporated in epoxy polymer matrix have been achieved. The X-ray diffraction (XRD) studies show the formation of zinc stearate on ZnO nanoparticles as the confirmation of SA-functionalization of ZnO nanoparticles in the thin films. Morphological analyses reveal the presence of micro-holes with the presence of irregular nanoparticles. The measured root mean square (rms) roughness of the thin film is found to be 12 ± 1 μm with the adhesion of 5B on both glass and aluminum substrates. The wetting property shows that the surface of the film is superhydrophobic with the contact angle of water of 156 ± 4° having contact angle hysteresis (CAH) of 4 ± 2°. The average terminal velocity in the water of the as-received glass spheres and superhydrophobic spheres were found to be 0.66 ± 0.01 m/s and 0.72 ± 0.01 m/s respectively. Consequently, the calculated average coefficients of the surface drag of the as-received glass sphere and superhydrophobic glass sphere were 2.30 ± 0.01 and 1.93 ± 0.03, respectively. Hence, the drag reduction on the surface of superhydrophobic glass sphere is found to be approximately 16% lower than as-received glass sphere

  6. The Effect of Sodium Hydroxide on Drag Reduction using a Biopolymer.

    Directory of Open Access Journals (Sweden)

    Singh Harvin Kaur A/P Gurchran

    2014-07-01

    Full Text Available Drag reduction is observed as reduced frictional pressure losses under turbulent flow conditions and hence, substantially increases the flowrate of the fluid. Practical application includes water flooding system, pipeline transport and drainage system. Drag reduction agent, such as polymers, can be introduced to increase the flowrate of water flowing, reducing the water accumulation in the system and subsequently lesser possibility of heavy flooding. Currently used polymer as drag reduction agents is carboxymethylcellulose, to name one. This is a synthetic polymer which will seep into the ground and further harm our environment in excessive use of accumulation. A more environmentally-friendly drag reduction agent, such as the polymer derived from natural sources or biopolymer, is then required for such purpose. As opposed to the synthetic polymers, the potential of biopolymers as drag reduction agents, especially those derived from a local plant source, are not extensively explored. The drag reduction of a polymer produced from a local plant source within the turbulent regime will be explored and assessed in this study using a rheometer where a reduced a torque produced can be perceived as a reduction of drag. The cellulose powder was converted to carboxymethylcellulose (CMC by etherification process using sodium monochloroacetate and sodium hydroxide. The carboxymethylation reaction then was optimized against concentration of NaOH. The research is structured to focus on producing the biopolymer and also assess the drag reduction ability of the biopolymer produced against concentration of sodium hydroxide.

  7. Toy Model of Frame-Dragging Magnetosphere for the M87 Jet

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Toy Model of Frame-Dragging Magnetosphere for the M87 Jet ... The outermost layer of jet is driven by the frame-dragging effect in the Kerr ... All these have helped shorten the publication time and have improved the visibility ...

  8. Coulomb Drag as a Probe of Coupled Plasmon Modes in Parallel Quantum Wells

    DEFF Research Database (Denmark)

    Flensberg, Karsten; Hu, Ben Yu-Kuang

    1994-01-01

    parameters. The acoustic mode causes a sharp upturn in the scaled drag rate with increasing temperature at T≈0.2TF. Other experimental signatures of the plasmon-dominated drag rate are a d-3 dependence on the well separation d and a peak as a function of relative densities at matched Fermi velocities....

  9. Can Hall drag be observed in Coulomb coupled quantum wells in a magnetic field?

    DEFF Research Database (Denmark)

    Hu, Ben Yu-Kuang

    1997-01-01

    We study the transresistivity rho(21) (or equivalently, the drag rate) of two Coulomb-coupled quantum wells in the presence of a perpendicular magnetic field, using semi-classical transport theory. Elementary arguments seem to preclude any possibility of observation of ''Hall drag'' (i.e., a non...

  10. Flow Patterns and Thermal Drag in a One-Dimensional Inviscid Channel with Heating or Cooling

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    In this paper investigations on the flow patterns and the thermal drag phenomenon in one -dimensional inviscid channel flow with heating or cooling are described and discussed:expressions of flow rate ratio and thermal drag coefficient for different flow patterns and its physical mechanism are presented.

  11. Experimental Study of Drag Resistance using a Laboratory Scale Rotary Set-Up

    DEFF Research Database (Denmark)

    Erik Weinell, Claus; Olsen, Kenneth N.; Christoffersen, Martin W.

    2003-01-01

    This work covers an experimental study of the drag resistance of different painted surfaces and simulated large-scale irregularities, viz. dry spraying, weld seams, barnacle fouling and paint remains. A laboratory scale rotary set-up was used to determine the drag resistance, and the surface...

  12. Magnon-drag thermopower and Nernst coefficient in Fe, Co, and Ni

    NARCIS (Netherlands)

    Watzman, Sarah J.; Duine, Rembert A.|info:eu-repo/dai/nl/304830127; Tserkovnyak, Yaroslav; Boona, Stephen R.; Jin, Hyungyu; Prakash, Arati; Zheng, Yuanhua; Heremans, Joseph P.

    2016-01-01

    Magnon-drag is shown to dominate the thermopower of elemental Fe from 2 to 80 K and of elemental Co from 150 to 600 K; it is also shown to contribute to the thermopower of elemental Ni from 50 to 500 K. Two theoretical models are presented for magnon-drag thermopower. One is a hydrodynamic theory

  13. Magnon-drag thermopower and Nernst coefficient in Fe, Co and Ni

    NARCIS (Netherlands)

    Watzman, S.J.; Duine, R.A.; Tserkovnyak, Y.; Jin, H.; Prakash, A.; Zheng, Y.; Heremans, J.P.

    2016-01-01

    Magnon drag is shown to dominate the thermopower of elemental Fe from 2 to 80 K and of elemental Co from 150 to 600 K; it is also shown to contribute to the thermopower of elemental Ni from 50 to 500 K. Two theoretical models are presented for magnon-drag thermopower. One is a hydrodynamic theory

  14. Optical-phonon-induced frictional drag in coupled two-dimensional electron gases

    DEFF Research Database (Denmark)

    Hu, Ben Yu-Kuang

    1998-01-01

    The role of optical phonons in frictional drag between two adjacent but electrically isolated two-dimensional electron gases is investigated. Since the optical phonons in III-V materials have a considerably larger coupling to electrons than acoustic phonons (which are the dominant drag mechanism ...

  15. Effect of structure height on the drag reduction performance using rotating disk apparatus

    Energy Technology Data Exchange (ETDEWEB)

    Rashed, Musaab K; Salleh, Mohamad Amran Mohd; Ismail, M Halim Shah [Department of Chemical and Environmental Engineering, Faculty of Engineering, University Putra Malaysia (Malaysia); Abdulbari, Hayder A, E-mail: hayder.bari@gmail.com [Center of Excellence for Advanced Research in Fluid Flow, Universiti Malaysia Pahang (Malaysia)

    2017-02-15

    The drag reduction characteristics in a rotating disk apparatus were investigated by using structured disks with different riblet types and dimensions. Two disk types were fabricated with right angle triangular (RAT) grooves and space v-shape (SV) grooves, with six dimensions for each type. A high-accuracy rotating disk apparatus was fabricated and then used to investigate the turbulent drag reduction characterization of the disk in diesel fuel. In this work, the effects of several parameters are investigated; riblet types, riblet dimensions, and rotational disk speed (rpm) on the drag reduction performance. It was found that the surface structure of the disk reduced the drag, this was clearly seen from the comparison of torque values of smooth and structured disks. Drag reduction for structured disks was higher than that for smooth disks, and SV-grooves showed better drag reduction performance than RAT-grooves. In addition, it was observed that the drag reduction performance increased with decreasing groove height for both groove types. The maximum drag reduction achieved in this study was 37.368% for SV-groove at 1000 rpm, compared with 30% for RAT-groove, at the same rotational speed. (paper)

  16. Superfluid drag in the two-component Bose-Hubbard model

    Science.gov (United States)

    Sellin, Karl; Babaev, Egor

    2018-03-01

    In multicomponent superfluids and superconductors, co- and counterflows of components have, in general, different properties. A. F. Andreev and E. P. Bashkin [Sov. Phys. JETP 42, 164 (1975)] discussed, in the context of He3/He4 superfluid mixtures, that interparticle interactions produce a dissipationless drag. The drag can be understood as a superflow of one component induced by phase gradients of the other component. Importantly, the drag can be both positive (entrainment) and negative (counterflow). The effect is known to have crucial importance for many properties of diverse physical systems ranging from the dynamics of neutron stars and rotational responses of Bose mixtures of ultracold atoms to magnetic responses of multicomponent superconductors. Although substantial literature exists that includes the drag interaction phenomenologically, only a few regimes are covered by quantitative studies of the microscopic origin of the drag and its dependence on microscopic parameters. Here we study the microscopic origin and strength of the drag interaction in a quantum system of two-component bosons on a lattice with short-range interaction. By performing quantum Monte Carlo simulations of a two-component Bose-Hubbard model we obtain dependencies of the drag strength on the boson-boson interactions and properties of the optical lattice. Of particular interest are the strongly correlated regimes where the ratio of coflow and counterflow superfluid stiffnesses can diverge, corresponding to the case of saturated drag.

  17. Fluid Mechanics, Drag Reduction and Advanced Configuration Aeronautics

    Science.gov (United States)

    Bushnell, Dennis M.

    2000-01-01

    This paper discusses Advanced Aircraft configurational approaches across the speed range, which are either enabled, or greatly enhanced, by clever Flow Control. Configurations considered include Channel Wings with circulation control for VTOL (but non-hovering) operation with high cruise speed, strut-braced CTOL transports with wingtip engines and extensive ('natural') laminar flow control, a midwing double fuselage CTOL approach utilizing several synergistic methods for drag-due-to-lift reduction, a supersonic strut-braced configuration with order of twice the L/D of current approaches and a very advanced, highly engine flow-path-integrated hypersonic cruise machine. This paper indicates both the promise of synergistic flow control approaches as enablers for 'Revolutions' in aircraft performance and fluid mechanic 'areas of ignorance' which impede their realization and provide 'target-rich' opportunities for Fluids Research.

  18. LISA Pathfinder drag-free control and system implications

    International Nuclear Information System (INIS)

    Fichter, Walter; Gath, Peter; Vitale, Stefano; Bortoluzzi, Daniele

    2005-01-01

    The top-level requirement of the LISA Pathfinder mission is the verification of pure relative free fall between two test masses with an accuracy of about 3 x 10 -14 m s -2 Hz -1/2 in a measurement bandwidth between 1 mHz and 30 mHz. The drag-free control system is one of the key technology elements that shall be verified. Its design is strongly connected to the overall system and experimental design, in particular, via the following issues: the differential test mass motion and thus the science measurements depend on the control system; design constraints, such as negative stiffness of test masses and electrostatic actuation cross-talk, have an impact on science and control system performance; derived requirements for control system components, in particular, the micro-propulsion system, must be within reasonable and feasible limits. In this paper, the control design approach is outlined and the system-related issues are addressed

  19. Thermal design of AOTV heatshields for a conical drag brake

    Science.gov (United States)

    Pitts, W. C.; Murbach, M. S.

    1985-01-01

    Results are presented from an on-going study of the thermal performance of thermal protection systems for a conical drag brake type AOTV. Three types of heatshield are considered: rigid ceramic insulation, flexible ceramic blankets, and ceramic cloths. The results for the rigid insulation apply to other types of AOTV as well. Charts are presented in parametric form so that they may be applied to a variety of missions and vehicle configurations. The parameters considered include: braking maneuver heat flux and total heat load, heatshield material and thickness, heatshield thermal mass and conductivity, absorptivity and emissivity of surfaces, thermal mass of support structure, and radiation transmission through thin heatshields. Results of temperature calculations presented show trends with and sensitivities to these parameters. The emphasis is on providing information that will be useful in estimating the minimum required mass of these heatshield materials.

  20. Drag Reduction of an Airfoil Using Deep Learning

    Science.gov (United States)

    Jiang, Chiyu; Sun, Anzhu; Marcus, Philip

    2017-11-01

    We reduced the drag of a 2D airfoil by starting with a NACA-0012 airfoil and used deep learning methods. We created a database which consists of simulations of 2D external flow over randomly generated shapes. We then developed a machine learning framework for external flow field inference given input shapes. Past work which utilized machine learning in Computational Fluid Dynamics focused on estimations of specific flow parameters, but this work is novel in the inference of entire flow fields. We further showed that learned flow patterns are transferable to cases that share certain similarities. This study illustrates the prospects of deeper integration of data-based modeling into current CFD simulation frameworks for faster flow inference and more accurate flow modeling.

  1. Helicopter fuselage drag - combined computational fluid dynamics and experimental studies

    Science.gov (United States)

    Batrakov, A.; Kusyumov, A.; Mikhailov, S.; Pakhov, V.; Sungatullin, A.; Valeev, M.; Zherekhov, V.; Barakos, G.

    2015-06-01

    In this paper, wind tunnel experiments are combined with Computational Fluid Dynamics (CFD) aiming to analyze the aerodynamics of realistic fuselage configurations. A development model of the ANSAT aircraft and an early model of the AKTAI light helicopter were employed. Both models were tested at the subsonic wind tunnel of KNRTU-KAI for a range of Reynolds numbers and pitch and yaw angles. The force balance measurements were complemented by particle image velocimetry (PIV) investigations for the cases where the experimental force measurements showed substantial unsteadiness. The CFD results were found to be in fair agreement with the test data and revealed some flow separation at the rear of the fuselages. Once confidence on the CFD method was established, further modifications were introduced to the ANSAT-like fuselage model to demonstrate drag reduction via small shape changes.

  2. Ontogeny of lift and drag production in ground birds.

    Science.gov (United States)

    Heers, Ashley M; Tobalske, Bret W; Dial, Kenneth P

    2011-03-01

    The juvenile period is often a crucial interval for selective pressure on locomotor ability. Although flight is central to avian biology, little is known about factors that limit flight performance during development. To improve understanding of flight ontogeny, we used a propeller (revolving wing) model to test how wing shape and feather structure influence aerodynamic performance during development in the precocial chukar partridge (Alectoris chukar, 4 to >100 days post hatching). We spun wings in mid-downstroke posture and measured lift (L) and drag (D) using a force plate upon which the propeller assembly was mounted. Our findings demonstrate a clear relationship between feather morphology and aerodynamic performance. Independent of size and velocity, older wings with stiffer and more asymmetrical feathers, high numbers of barbicels and a high degree of overlap between barbules generate greater L and L:D ratios than younger wings with flexible, relatively symmetrical and less cohesive feathers. The gradual transition from immature feathers and drag-based performance to more mature feathers and lift-based performance appears to coincide with ontogenetic transitions in locomotor capacity. Younger birds engage in behaviors that require little aerodynamic force and that allow D to contribute to weight support, whereas older birds may expand their behavioral repertoire by flapping with higher tip velocities and generating greater L. Incipient wings are, therefore, uniquely but immediately functional and provide flight-incapable juveniles with access to three-dimensional environments and refugia. Such access may have conferred selective advantages to theropods with protowings during the evolution of avian flight.

  3. On the Fetch Dependent Drag Coefficient over Coastal and Inland Seas

    DEFF Research Database (Denmark)

    Geernaert, G. L.; Smith, J. A.

    a maximum when the phase speed of the dominant wind wave has a value near 7 u*, where u* is the friction velocity. This corresponds to a maximum near 2 km fetch during moderate windspeed, and the maximum value of the drag coefficient corresponds to an increased fetch of 13 km for windspeeds of 20 m/sec. We......The drag coefficient has been postulated by many investigators to depend on fetch. For constant windspeed and stability, laboratory data generally show an increasing drag coefficient with fetch while field observations show a decreasing dependence. In this study, we show that if one combines...... the spectral form of the roughness length proposed by Kitaigorodskii with the JONSWAP wave spectrum and extrapolate to very short fetch, then the predicted drag coefficient exhibits a behaviour which coarsely reproduces field and laboratory observations. The results indicate that the drag coefficient exhibits...

  4. Effect of Polymer Type and Mixing of Polymers on Drag Reduction in Turbulent Pipe Flow

    Directory of Open Access Journals (Sweden)

    Salam Hadi Hussein

    2017-05-01

    Full Text Available The paper reports on studies on effect of the type of polymer on drag reduction. The study conducted through circular pipe using Carboxy Methyl Cellulose (CMC, Xanthan gum (XG and their mixing in equal ratios as additives in pipe of diameter 0.0381m. The study covered range of parameters like concentration, mean velocity and angle of inclination of pipe. The maximum drag reduction observed was about 58%, 46% and 46% for the three polymers respectively. It is found that the drag reduction for the mixture is close to the drag reduction for XG polymer. The SPSS program has been used for correlate the data that have been obtained. The drag reduction percentage is correlated in terms of Reynolds number Re, additive concentration C (ppm and angle of inclination of pipe (deg, and the relations obtained is mentioned.

  5. Leidenfrost Vapor Layers Reduce Drag without the Crisis in High Viscosity Liquids

    KAUST Repository

    Vakarelski, Ivan Uriev

    2016-09-08

    The drag coefficient CD of a solid smooth sphere moving in a fluid is known to be only a function of the Reynolds number Re and diminishes rapidly at the drag crisis around Re∼3×105. A Leidenfrost vapor layer on a hot sphere surface can trigger the onset of the drag crisis at a lower Re. By using a range of high viscosity perfluorocarbon liquids, we show that the drag reduction effect can occur over a wide range of Re, from as low as ∼600 to 105. The Navier slip model with a viscosity dependent slip length can fit the observed drag reduction and wake shape. © 2016 American Physical Society.

  6. Large Fizeau's light-dragging effect in a moving electromagnetically induced transparent medium.

    Science.gov (United States)

    Kuan, Pei-Chen; Huang, Chang; Chan, Wei Sheng; Kosen, Sandoko; Lan, Shau-Yu

    2016-10-03

    As one of the most influential experiments on the development of modern macroscopic theory from Newtonian mechanics to Einstein's special theory of relativity, the phenomenon of light dragging in a moving medium has been discussed and observed extensively in different types of systems. To have a significant dragging effect, the long duration of light travelling in the medium is preferred. Here we demonstrate a light-dragging experiment in an electromagnetically induced transparent cold atomic ensemble and enhance the dragging effect by at least three orders of magnitude compared with the previous experiments. With a large enhancement of the dragging effect, we realize an atom-based velocimeter that has a sensitivity two orders of magnitude higher than the velocity width of the atomic medium used. Such a demonstration could pave the way for motional sensing using the collective state of atoms in a room temperature vapour cell or solid state material.

  7. Effects of stern-foil submerged elevation on the lift and drag of a hydrofoil craft

    Science.gov (United States)

    Suastika, K.; Apriansyah

    2018-03-01

    Effects of the stern-foil submerged elevation on the lift and drag of a hydrofoil craft are studied by using computational fluid dynamics (CFD) and by considering three alternative stern-foil submerged elevations. The submerged elevation of the front foil is kept constant in all the alternatives. From among the alternatives, the deepest stern-foil placement results in the highest stern-foil lift with the highest foil’s lift-to-drag ratio. However, considering the lift-to-drag ratio of the whole foil-strut-hull system, the shallowest stern-foil placement results in the highest lift-to-drag ratio. The struts and the foil’s submerged elevation significantly affects the drag of the whole foil-strut-hull system.

  8. An experimental determination of the drag coefficient of a Mens 8+ racing shell.

    Science.gov (United States)

    Buckmann, James G; Harris, Samuel D

    2014-01-01

    This study centered around an experimental analysis of a Mens Lightweight Eight racing shell and, specifically, determining an approximation for the drag coefficient. A testing procedure was employed that used a Global Positioning System (GPS) unit in order to determine the acceleration and drag force on the shell, and through calculations yield a drag coefficient. The testing was run over several days in numerous conditions, and a 95% confidence interval was established to capture the results. The results obtained, over these varying trials, maintained a successful level of consistency. The significance of this study transcends the determination an approximation for the drag coefficient of the racing shell; it defined a successful means of quantifying performance of the shell itself. The testing procedures outlined in the study represent a uniform means of evaluating the factors that influence drag on the shell, and thus influence speed.

  9. Leidenfrost Vapor Layers Reduce Drag without the Crisis in High Viscosity Liquids

    KAUST Repository

    Vakarelski, Ivan Uriev; Berry, Joseph D.; Chan, Derek Y C; Thoroddsen, Sigurdur T

    2016-01-01

    The drag coefficient CD of a solid smooth sphere moving in a fluid is known to be only a function of the Reynolds number Re and diminishes rapidly at the drag crisis around Re∼3×105. A Leidenfrost vapor layer on a hot sphere surface can trigger the onset of the drag crisis at a lower Re. By using a range of high viscosity perfluorocarbon liquids, we show that the drag reduction effect can occur over a wide range of Re, from as low as ∼600 to 105. The Navier slip model with a viscosity dependent slip length can fit the observed drag reduction and wake shape. © 2016 American Physical Society.

  10. Superhydrophobic and polymer drag reduction in turbulent Taylor-Couette flow

    Science.gov (United States)

    Rajappan, Anoop; McKinley, Gareth H.

    2017-11-01

    We use a custom-built Taylor-Couette apparatus (radius ratio η = 0.75) to study frictional drag reduction by dilute polymer solutions and superhydrophobic (SH) surfaces in turbulent flows for 15000 analysis. We also investigate drag reduction by dilute polymer solutions, and show that natural biopolymers from plant mucilage can be an inexpensive and effective alternative to synthetic polymers in drag reduction applications, approaching the same maximum drag reduction asymptote. Finally we explore combinations of the two methods - one arising from wall slip and the other due to changes in turbulence dynamics in the bulk flow - and find that the two effects are not additive; interestingly, the effectiveness of polymer drag reduction is drastically reduced in the presence of an SH coating on the wall. This study was financially supported by the Office of Naval Research (ONR) through Contract No. 3002453814.

  11. Wave drag as the objective function in transonic fighter wing optimization

    Science.gov (United States)

    Phillips, P. S.

    1984-01-01

    The original computational method for determining wave drag in a three dimensional transonic analysis method was replaced by a wave drag formula based on the loss in momentum across an isentropic shock. This formula was used as the objective function in a numerical optimization procedure to reduce the wave drag of a fighter wing at transonic maneuver conditions. The optimization procedure minimized wave drag through modifications to the wing section contours defined by a wing profile shape function. A significant reduction in wave drag was achieved while maintaining a high lift coefficient. Comparisons of the pressure distributions for the initial and optimized wing geometries showed significant reductions in the leading-edge peaks and shock strength across the span.

  12. Preliminary Theoretical Interpretation of the Tajmar Frame Dragging Effect Through the GEM Theory

    International Nuclear Information System (INIS)

    Brandenburg, John

    2009-01-01

    A preliminary theoretical explanation for the large amplitude frame dragging effect seen by Tajmar et al.(2007) is proposed. A simple theory of quantum photon fields mediating electrodynamics is derived based on concepts from QED. These are then expressed as quantum wave functions for rotating EM systems. Based on the GEM theory, it is proposed that gravitational frame dragging relies on similar photon wave functions. The constructive interference of the frame dragging fields with co-rotating EM photon fields coupled to Bose-Einstein components in matter at low temperatures results in a large frame dragging term due to a mixed gravity-EM term that is larger by a factor of approximately 10 20 than ordinary frame dragging.

  13. On the Effect of Rigid Swept Surface Waves on Turbulent Drag

    Science.gov (United States)

    Denison, M.; Wilkinson, S. P.; Balakumar, P.

    2015-01-01

    Passive turbulent drag reduction techniques are of interest as a cost effective means to improve air vehicle fuel consumption. In the past, rigid surface waves slanted at an angle from the streamwise direction were deemed ineffective to reduce skin friction drag due to the pressure drag that they generate. A recent analysis seeking similarities to the spanwise shear stress generated by spatial Stokes layers suggested that there may be a range of wavelength, amplitude, and orientation in which the wavy surface would reduce turbulent drag. The present work explores, by experiments and Direct Numerical Simulations (DNS), the effect of swept wavy surfaces on skin friction and pressure drag. Plates with shallow and deep wave patterns were rapid-prototyped and tested using a drag balance in the 7x11 inch Low-Speed Wind Tunnel at the NASA LaRC Research Center. The measured drag o set between the wavy plates and the reference at plate is found to be within the experimental repeatability limit. Oil vapor flow measurements indicate a mean spanwise flow over the deep waves. The turbulent flow in channels with at walls, swept wavy walls and spatial Stokes spanwise velocity forcing was simulated at a friction Reynolds number of two hundred. The time-averaged and dynamic turbulent flow characteristics of the three channel types are compared. The drag obtained for the channel with shallow waves is slightly larger than for the at channel, within the range of the experiments. In the case of the large waves, the simulation over predicts the drag. The shortcomings of the Stokes layer analogy model for the estimation of the spanwise shear stress and drag are discussed.

  14. Drag and Lift Estimation from 3-D Velocity Field Data Measured by Multi-Plane Stereo PIV

    OpenAIRE

    加藤, 裕之; 松島, 紀佐; 上野, 真; 小池, 俊輔; 渡辺, 重哉; Kato, Hiroyuki; Matsushima, Kisa; Ueno, Makoto; Koike, Shunsuke; Watanabe, Shigeya

    2013-01-01

    For airplane design, it is crucial to have tools that can accurately predict airplane drag and lift. Usually drag and lift prediction methods are force measurement using wind tunnel balance. Unfortunately, balance data do not provide information contribution of airplane to components to drag and lift for more precise and competitive airplane design. To obtain such information, a wake integration method for use drag and lift estimation was developed for use in wake survey data analysis. Wake s...

  15. Bag-breakup control of surface drag in hurricanes

    Science.gov (United States)

    Troitskaya, Yuliya; Zilitinkevich, Sergej; Kandaurov, Alexander; Ermakova, Olga; Kozlov, Dmitry; Sergeev, Daniil

    2016-04-01

    Air-sea interaction at extreme winds is of special interest now in connection with the problem of the sea surface drag reduction at the wind speed exceeding 30-35 m/s. This phenomenon predicted by Emanuel (1995) and confirmed by a number of field (e.g., Powell, et al, 2003) and laboratory (Donelan et al, 2004) experiments still waits its physical explanation. Several papers attributed the drag reduction to spume droplets - spray turning off the crests of breaking waves (e.g., Kudryavtsev, Makin, 2011, Bao, et al, 2011). The fluxes associated with the spray are determined by the rate of droplet production at the surface quantified by the sea spray generation function (SSGF), defined as the number of spray particles of radius r produced from the unit area of water surface in unit time. However, the mechanism of spume droplets' formation is unknown and empirical estimates of SSGF varied over six orders of magnitude; therefore, the production rate of large sea spray droplets is not adequately described and there are significant uncertainties in estimations of exchange processes in hurricanes. Herewith, it is unknown what is air-sea interface and how water is fragmented to spray at hurricane wind. Using high-speed video, we observed mechanisms of production of spume droplets at strong winds by high-speed video filming, investigated statistics and compared their efficiency. Experiments showed, that the generation of the spume droplets near the wave crest is caused by the following events: bursting of submerged bubbles, generation and breakup of "projections" and "bag breakup". Statistical analysis of results of these experiments showed that the main mechanism of spray-generation is attributed to "bag-breakup mechanism", namely, inflating and consequent blowing of short-lived, sail-like pieces of the water-surface film. Using high-speed video, we show that at hurricane winds the main mechanism of spray production is attributed to "bag-breakup", namely, inflating and

  16. On the Minimum Induced Drag of Wings -or- Thinking Outside the Box

    Science.gov (United States)

    Bowers, Albion H.

    2011-01-01

    Of all the types of drag, induced drag is associated with the creation and generation of lift over wings. Induced drag is directly driven by the span load that the aircraft is flying at. The tools by which to calculate and predict induced drag we use were created by Ludwig Prandtl in 1903. Within a decade after Prandtl created a tool for calculating induced drag, Prandtl and his students had optimized the problem to solve the minimum induced drag for a wing of a given span, formalized and written about in 1920. This solution is quoted in textbooks extensively today. Prandtl did not stop with this first solution, and came to a dramatically different solution in 1932. Subsequent development of this 1932 solution solves several aeronautics design difficulties simultaneously, including maximum performance, minimum structure, minimum drag loss due to control input, and solution to adverse yaw without a vertical tail. This presentation lists that solution by Prandtl, and the refinements by Horten, Jones, Kline, Viswanathan, and Whitcomb.

  17. Discovery of riblets in a bird beak (Rynchops) for low fluid drag.

    Science.gov (United States)

    Martin, Samuel; Bhushan, Bharat

    2016-08-06

    Riblet structures found on fast-swimming shark scales, such as those found on a mako shark, have been shown to reduce fluid drag. In previous experimental and modelling studies, riblets have been shown to provide drag reduction by lifting vortices formed in turbulent flow, decreasing overall shear stresses. Skimmer birds (Rynchops) are the only birds to catch fish in flight by flying just above the water surface with a submerged beak to fish for food. Because they need to quickly catch prey, reducing drag on their beak is advantageous. For the first time, riblet structures found on the beak of the skimmer bird have been studied experimentally and computationally for low fluid drag properties. In this study, skimmer replicas were studied for drag reduction through pressure drop in closed-channel, turbulent water flow. Pressure drop measurements are compared for black and yellow skimmer beaks in two configurations, and mako shark skin. In addition, two configurations of skimmer beak were modelled to compare drag properties and vortex structures. Results are discussed, and a conceptual model is presented to explain a possible drag reduction mechanism in skimmers.This article is part of the themed issue 'Bioinspired hierarchically structured surfaces for green science'. © 2016 The Author(s).

  18. Modification of near-wall coherent structures in polymer drag reduced flow: simulation

    Science.gov (United States)

    Dubief, Yves; White, Christopher; Shaqfeh, Eric; Moin, Parviz; Lele, Sanjiva

    2002-11-01

    Polymer drag reduced flows are investigated through direct numerical simulations of viscoelastic flows. The solver for the viscoelastic model (FENE-P) is based on higher-order finite difference schemes and a novel implicit time integration method. Its robustness allows the simulation of all drag reduction (DR) regimes from the onset to the maximum drag reduction (MDR). It also permits the use of realistic polymer length and concentration. The maximum polymer extension in our simulation matches that of a polystyrene molecule of 10^6 molecular weight. Two distinct regimes of polymer drag reduced flows are observed: at low drag reduction (LDR, DR< 40-50%), the near-wall structure is essentially similar to Newtonian wall turbulence whereas the high drag reduction regime (HDR, DR from 40-50% to MDR) shows significant differences in the organization of the coherent structures. The 3D information provided by numerical simulations allows the determination of the interaction of polymers and near-wall coherent structures. To isolate the contribution of polymers in the viscous sublayer, the buffer and the outer region of the flow, numerical experiments are performed where the polymer concentration is varied in the wall-normal direction. Finally a mechanism of polymer drag reduction derived from our results and PIV measurements is discussed.

  19. Grafted natural polymer as new drag reducing agent: An experimental approach

    Directory of Open Access Journals (Sweden)

    Abdulbari Hayder A.

    2012-01-01

    Full Text Available The present investigation introduces a new natural drag reducing agent which has the ability to improve the flow in pipelines carrying aqueous or hydrocarbon liquids in turbulent flow. Okra (Abelmoschus esculentus mucilage drag reduction performance was tested in water and hydrocarbon (gas-oil media after grafting. The drag reduction test was conducted in a buildup closed loop liquid circulation system consists of two pipes 0.0127 and 0.0381 m Inside Diameter (ID, four testing sections in each pipe (0.5 to 2.0 m, tank, pump and pressure transmitters. Reynolds number (Re, additive concentration and the transported media type (water and gas-oil, were the major drag reduction variables investigated. The experimental results show that, new additive drag reduction ability is high with maximum percentage of drag reduction (%Dr up to 60% was achieved. The experimental results showed that the drag reduction ability increased by increasing the additive concentration. The %Dr was found to increase by increasing the Re by using the water-soluble additive while it was found to decrease by increasing the Re when using the oil-soluble additive. The %Dr was higher in the 0.0381 m ID pipe. Finally, the grafted and natural mucilage showed high resistance to shear forces when circulated continuously for 200 seconds in the closed-loop system.

  20. Parameterizing Subgrid-Scale Orographic Drag in the High-Resolution Rapid Refresh (HRRR) Atmospheric Model

    Science.gov (United States)

    Toy, M. D.; Olson, J.; Kenyon, J.; Smirnova, T. G.; Brown, J. M.

    2017-12-01

    The accuracy of wind forecasts in numerical weather prediction (NWP) models is improved when the drag forces imparted on atmospheric flow by subgrid-scale orography are included. Without such parameterizations, only the terrain resolved by the model grid, along with the small-scale obstacles parameterized by the roughness lengths can have an effect on the flow. This neglects the impacts of subgrid-scale terrain variations, which typically leads to wind speeds that are too strong. Using statistical information about the subgrid-scale orography, such as the mean and variance of the topographic height within a grid cell, the drag forces due to flow blocking, gravity wave drag, and turbulent form drag are estimated and distributed vertically throughout the grid cell column. We recently implemented the small-scale gravity wave drag paramterization of Steeneveld et al. (2008) and Tsiringakis et al. (2017) for stable planetary boundary layers, and the turbulent form drag parameterization of Beljaars et al. (2004) in the High-Resolution Rapid Refresh (HRRR) NWP model developed at the National Oceanic and Atmospheric Administration (NOAA). As a result, a high surface wind speed bias in the model has been reduced and small improvement to the maintenance of stable layers has also been found. We present the results of experiments with the subgrid-scale orographic drag parameterization for the regional HRRR model, as well as for a global model in development at NOAA, showing the direct and indirect impacts.

  1. Numerical simulation of drag-reducing channel flow by using bead-spring chain model

    International Nuclear Information System (INIS)

    Fujimura, M.; Atsumi, T.; Mamori, H.; Iwamoto, K.; Murata, A.; Masuda, M.; Ando, H.

    2017-01-01

    Highlights: • Numerical simulations of drag-reduced turbulent flow by polymer additives were performed by using a discrete element model. • A decreasing pressure-strain correlation mainly contributes to drag reduction by polymer addition. • Energy transport by the polymer attenuates the turbulence. • The viscoelastic effects on the drag-reducing flow are intensified with increasing relaxation time of polymer. • The polymer energy transport is related to the orientation of the polymer. - Abstract: Numerical simulations of the drag-reducing turbulent channel flow caused by polymer addition are performed. A bead-spring chain model is employed as a model of polymer aggregation. The model consists of beads and springs to represent the polymer dynamics. Three drag-reduction cases are studied with different spring constants that correspond to the relaxation time of the polymer. The energy budget is mainly focused upon to discuss the drag-reduction mechanism. Our results show that a decreasing pressure-strain correlation mainly contributes to strengthening the anisotropy of the turbulence. Furthermore, energy transport by the polymer models attenuates the turbulence. These viscoelastic effects on the drag-reducing flow are intensified with decreasing spring constant. By visualizing the flow field, it is found that this polymer energy transport is related to the orientation of the polymer.

  2. On the Decrease of the Oceanic Drag Coefficient in High Winds

    Science.gov (United States)

    Donelan, Mark A.

    2018-02-01

    The sheltering coefficient - prefixing Jeffreys' concept of the exponential wave growth rate at a gas-liquid interface - is shown to be Reynolds number dependent from laboratory measurements of waves and Reynolds stresses. There are two turbulent flow regimes: wind speed range of 2.5 to 30 m/s where the drag coefficients increase with wind speed, and wind speed range of 30 to 50 m/s where sheltering/drag coefficients decrease/saturate with wind speed. By comparing model calculations of drag coefficients - using a fixed sheltering coefficient - with ocean observations over a wind speed range of 1 to 50 m/s a similar Reynolds number dependence of the oceanic sheltering coefficient is revealed. In consequence the drag coefficient is a function of Reynolds number and wave age, and not just wind speed as frequently assumed. The resulting decreasing drag coefficient above 30 m/s is shown to be critical in explaining the rapid intensification so prominent in the climatology of Atlantic hurricanes. The Reynolds number dependence of the sheltering coefficient, when employed in coupled models, should lead to significant improvements in the prediction of intensification and decay of tropical cyclones. A calculation of curvature at the wave crest suggests that at wind speeds above 56.15 m/s all waves-breaking or not-induce steady flow separation leading to a minimum in the drag coefficient. This is further evidence of the veracity of the observations of the oceanic drag coefficient at high winds.

  3. Research on the aerodynamic characteristics of a lift drag hybrid vertical axis wind turbine

    Directory of Open Access Journals (Sweden)

    Xiaojing Sun

    2016-01-01

    Full Text Available Compared with a drag-type vertical axis wind turbines, one of the greatest advantages for a lift-type vertical axis wind turbines is its higher power coefficient (Cp. However, the lift-type vertical axis wind turbines is not a self-starting turbine as its starting torque is very low. In order to combine the advantage of both the drag-type and the lift-type vertical axis wind turbines, a lift drag hybrid vertical axis wind turbines was designed in this article and its aerodynamics and starting performance was studied in detail with the aid of computational fluid dynamics simulations. Numerical results indicate that the power coefficient of this lift drag hybrid vertical axis wind turbines declines when the distance between its drag-type blades and the center of rotation of the turbine rotor increases, whereas its starting torque can be significantly improved. Studies also show that unlike the lift-type vertical axis wind turbines, this lift drag hybrid-type vertical axis wind turbines could be able to solve the problem of low start-up torque. However, the installation position of the drag blade is very important. If the drag blade is mounted very close to the spindle, the starting torque of the lift drag hybrid-type vertical axis wind turbines may not be improved at all. In addition, it has been found that the power coefficient of the studied vertical axis wind turbines is not as good as expected and possible reasons have been provided in this article after the pressure distribution along the surfaces of the airfoil-shaped blades of the hybrid turbine was analyzed.

  4. Departure of microscopic friction from macroscopic drag in molecular fluid dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Hanasaki, Itsuo [Institute of Engineering, Tokyo University of Agriculture and Technology, Naka-cho 2-24-16, Koganei, Tokyo 184-8588 (Japan); Fujiwara, Daiki; Kawano, Satoyuki, E-mail: kawano@me.es.osaka-u.ac.jp [Graduate School of Engineering Science, Osaka University, Machikaneyama-cho 1-3, Toyonaka, Osaka 560-8531 (Japan)

    2016-03-07

    Friction coefficient of the Langevin equation and drag of spherical macroscopic objects in steady flow at low Reynolds numbers are usually regarded as equivalent. We show that the microscopic friction can be different from the macroscopic drag when the mass is taken into account for particles with comparable scale to the surrounding fluid molecules. We illustrate it numerically by molecular dynamics simulation of chloride ion in water. Friction variation by the atomistic mass effect beyond the Langevin regime can be of use in the drag reduction technology as well as the electro or thermophoresis.

  5. Drag on a slip spherical particle moving in a couple stress fluid

    Directory of Open Access Journals (Sweden)

    E.A. Ashmawy

    2016-06-01

    Full Text Available The creeping motion of a rigid slip sphere in an unbounded couple stress fluid is investigated. The linear slip boundary condition and the vanishing couple stress condition are applied on the surface of the sphere. A simple formula for the drag force acting on a slip sphere translating in an unbounded couple stress fluid is obtained. Special cases of the deduced drag formula are concluded and compared with analogous results in the literature. The normalized drag force experienced by the fluid on the slip sphere is represented graphically and the effects of slip parameter and viscosity coefficients are discussed.

  6. Aerodynamic Drag Reduction for a Generic Truck Using Geometrically Optimized Rear Cabin Bumps

    Directory of Open Access Journals (Sweden)

    Abdellah Ait Moussa

    2015-01-01

    Full Text Available The continuous surge in gas prices has raised major concerns about vehicle fuel efficiency, and drag reduction devices offer a promising strategy. In this paper, we investigate the mechanisms by which geometrically optimized bumps, placed on the rear end of the cabin roof of a generic truck, reduce aerodynamic drag. The incorporation of these devices requires proper choices of the size, location, and overall geometry. In the following analysis we identify these factors using a novel methodology. The numerical technique combines automatic modeling of the add-ons, computational fluid dynamics and optimization using orthogonal arrays, and probabilistic restarts. Numerical results showed reduction in aerodynamic drag between 6% and 10%.

  7. Determining the drag coefficient of rotational symmetric objects falling through liquids

    International Nuclear Information System (INIS)

    Houari, Ahmed

    2012-01-01

    I will propose here a kinematic approach for measuring the drag coefficient of rotational symmetric objects falling through liquids. For this, I will show that one can obtain a measurement of the drag coefficient of a rotational symmetric object by numerically solving the equation of motion describing its fall through a known liquid contained in a vertical tube. The experimental value of the drag coefficient of an object with a particular shape is obtained by measuring the fall distance of the object at any recorded time along its entire falling path. (paper)

  8. Effects of Different Cutting Patterns and Experimental Conditions on the Performance of a Conical Drag Tool

    Science.gov (United States)

    Copur, Hanifi; Bilgin, Nuh; Balci, Cemal; Tumac, Deniz; Avunduk, Emre

    2017-06-01

    This study aims at determining the effects of single-, double-, and triple-spiral cutting patterns; the effects of tool cutting speeds on the experimental scale; and the effects of the method of yield estimation on cutting performance by performing a set of full-scale linear cutting tests with a conical cutting tool. The average and maximum normal, cutting and side forces; specific energy; yield; and coarseness index are measured and compared in each cutting pattern at a 25-mm line spacing, at varying depths of cut per revolution, and using two cutting speeds on five different rock samples. The results indicate that the optimum specific energy decreases by approximately 25% with an increasing number of spirals from the single- to the double-spiral cutting pattern for the hard rocks, whereas generally little effect was observed for the soft- and medium-strength rocks. The double-spiral cutting pattern appeared to be more effective than the single- or triple-spiral cutting pattern and had an advantage of lower side forces. The tool cutting speed had no apparent effect on the cutting performance. The estimation of the specific energy by the yield based on the theoretical swept area was not significantly different from that estimated by the yield based on the muck weighing, especially for the double- and triple-spiral cutting patterns and with the optimum ratio of line spacing to depth of cut per revolution. This study also demonstrated that the cutterhead and mechanical miner designs, semi-theoretical deterministic computer simulations and empirical performance predictions and optimization models should be based on realistic experimental simulations. Studies should be continued to obtain more reliable results by creating a larger database of laboratory tests and field performance records for mechanical miners using drag tools.

  9. Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes

    NARCIS (Netherlands)

    van der Geld, Ymke M.; Hellmark, Thomas; Selga, Daina; Heeringa, Peter; Huitema, Minke G.; Limburg, Pieter C.; Kallenberg, Cees G. M.

    2007-01-01

    Aim: In this study, we employed chimeric human/ mouse Proteinase 3 ( PR3) proteins as tools to induce an autoantibody response to PR3 in rats and mice. Method: Rats and mice were immunised with recombinant human PR3 ( HPR3), recombinant murine PR3 ( mPR3), single chimeric human/ mouse PR3 ( HHm,

  10. Nan Goldin: da Fotografia do Cotidiano à Visibilidade Drag Queen

    Directory of Open Access Journals (Sweden)

    Vivian Castro de Miranda

    2017-09-01

    Full Text Available Este trabalho tem como objetivo apresentar a biografia da fotógrafa americana Nan Goldin, a partir do recorte de sua produção datada entre as décadas de 1970 e 1990, em que ela fotografou a comunidade drag queen. A partir do cruzamento de informações vigentes em documentário (Série, 2004 e fontes relevantes (Guggenheim Museum, EUA; The Guardian, UK a quem a fotógrafa concedeu entrevistas ou foi notícia, procura-se explorar nesse texto a importância de uma produção que se insere no âmbito de questões caras ao contexto contemporâneo, que é a temática de gênero. Com a perspectiva teórica adotada, baseada principalmente nos apontamentos de Barthes (1984, é possível compreender o corpus analisado como resultante de um olhar sensível para o aspecto humano, com impacto para a discussão e aceitação do grupo social.

  11. Octopus-inspired drag cancelation by added mass pumping

    Science.gov (United States)

    Weymouth, Gabriel; Giorgio-Serchi, Francesco

    2016-11-01

    Recent work has shown that when an immersed body suddenly changes its size, such as a deflating octopus during rapid escape jetting, the body experiences large forces due to the variation of added-mass energy. We extend this line of research by investigating a spring-mass oscillator submerged in quiescent fluid subject to periodic changes in its volume. This system isolates the ability of the added-mass thrust to cancel the bluff body resistance (having no jet flow to confuse the analysis) and moves closer to studying how these effects would work in a sustained propulsion case by studying periodic shape-change instead of a "one-shot" escape maneuver. With a combination of analytical, numerical, and experimental results, we show that the recovery of added-mass kinetic energy can be used to completely cancel the drag of the fluid, driving the onset of sustained oscillations with amplitudes as large as four times the average body radius. Moreover, these results are fairly independent of the details of the shape-change kinematics as long as the Stokes number and shape-change number are large. In addition, the effective pumping frequency range based on parametric oscillator analysis is shown to predict large amplitude response region observed in the numerics and experiments.

  12. A probabilistic approach to the drag-based model

    Science.gov (United States)

    Napoletano, Gianluca; Forte, Roberta; Moro, Dario Del; Pietropaolo, Ermanno; Giovannelli, Luca; Berrilli, Francesco

    2018-02-01

    The forecast of the time of arrival (ToA) of a coronal mass ejection (CME) to Earth is of critical importance for our high-technology society and for any future manned exploration of the Solar System. As critical as the forecast accuracy is the knowledge of its precision, i.e. the error associated to the estimate. We propose a statistical approach for the computation of the ToA using the drag-based model by introducing the probability distributions, rather than exact values, as input parameters, thus allowing the evaluation of the uncertainty on the forecast. We test this approach using a set of CMEs whose transit times are known, and obtain extremely promising results: the average value of the absolute differences between measure and forecast is 9.1h, and half of these residuals are within the estimated errors. These results suggest that this approach deserves further investigation. We are working to realize a real-time implementation which ingests the outputs of automated CME tracking algorithms as inputs to create a database of events useful for a further validation of the approach.

  13. Drag reduction and improvement of material transport in creeping films

    Energy Technology Data Exchange (ETDEWEB)

    Scholle, M.; Rund, A.; Aksel, N. [University of Bayreuth, Department of Applied Mechanics and Fluid Dynamics, Bayreuth (Germany)

    2006-01-01

    It is widely accepted that for bodies in turbulent flows a reduction of skin friction can be reached if the surface of the body is provided with small ridges aligned in the local flow direction. This surprising and counterintuitive phenomenon is called the shark-skin effect, motivated from the dermal surface morphology of sharks. In the present article we examine the possibility of resistance reduction due to a rippled surface topography in Stokes flow. We especially analyse the influence of wall riblets perpendicular to the flow direction on the mean transport velocity in gravity-driven creeping film flows following the idea that eddies generated in the valleys of the riblets act like fluid roller bearings and hence may reduce drag. Using a theoretical treatment of the Stokes equations with complex function theory, parameter studies with varying flow rate, bottom amplitude and bottom shape are presented. For the given bottom shapes the maximum enhancement of transport velocity is found by optimising the film thickness. (orig.)

  14. On Wings of the Minimum Induced Drag: Spanload Implications for Aircraft and Birds

    Science.gov (United States)

    Bowers, Albion H.; Murillo, Oscar J.; Jensen, Robert (Red); Eslinger, Brian; Gelzer, Christian

    2016-01-01

    For nearly a century Ludwig Prandtl's lifting-line theory remains a standard tool for understanding and analyzing aircraft wings. The tool, said Prandtl, initially points to the elliptical spanload as the most efficient wing choice, and it, too, has become the standard in aviation. Having no other model, avian researchers have used the elliptical spanload virtually since its introduction. Yet over the last half-century, research in bird flight has generated increasing data incongruous with the elliptical spanload. In 1933 Prandtl published a little-known paper presenting a superior spanload: any other solution produces greater drag. We argue that this second spanload is the correct model for bird flight data. Based on research we present a unifying theory for superior efficiency and coordinated control in a single solution. Specifically, Prandtl's second spanload offers the only solution to three aspects of bird flight: how birds are able to turn and maneuver without a vertical tail; why birds fly in formation with their wingtips overlapped; and why narrow wingtips do not result in wingtip stall. We performed research using two experimental aircraft designed in accordance with the fundamentals of Prandtl's second paper, but applying recent developments, to validate the various potentials of the new spanload, to wit: as an alternative for avian researchers, to demonstrate the concept of proverse yaw, and to offer a new method of aircraft control and efficiency.

  15. Wavelet Spatial Energy Spectrums Studies on Drag Reduction by Micro-bubble Injection

    International Nuclear Information System (INIS)

    Ling Zhen; Yassin Hassan

    2006-01-01

    In this study, continuous wavelet transforms and spatial correlation techniques are employed to determine the space-localized wavenumber energy spectrum of the velocity signals in turbulent channel flow. The flow conditions correspond to single phase flow and micro-bubbles injected two phase flow. The wavelet energy spectrums demonstrate that the wavenumber (eddy size) content of the velocity signals is not only space-dependent but also micro-bubbles can impact the eddy size content. Visual observations of the wavelet energy spectrum spatial distribution was realized by using Particle Image Velocimetry (PIV) measurement technique. The two phase flow condition corresponds to a drag reduction of 38.4% with void fraction of 4.9%. The present results provide evidence that micro-bubbles in the boundary layer of a turbulent channel flow can help adjust the eddy size distributions near the wall. This can assist in explaining that micro-bubbles are performing as buffers to keep the energy of fluid particles going in stream-wise direction and reducing the energy of fluid particles going in normal direction. (authors)

  16. A Rigid Mid-Lift-to-Drag Ratio Approach to Human Mars Entry, Descent, and Landing

    Science.gov (United States)

    Cerimele, Christopher J.; Robertson, Edward A.; Sostaric, Ronald R.; Campbell, Charles H.; Robinson, Phil; Matz, Daniel A.; Johnson, Breanna J.; Stachowiak, Susan J.; Garcia, Joseph A.; Bowles, Jeffrey V.; hide

    2017-01-01

    Current NASA Human Mars architectures require delivery of approximately 20 metric tons of cargo to the surface in a single landing. A proposed vehicle type for performing the entry, descent, and landing at Mars associated with this architecture is a rigid, enclosed, elongated lifting body shape that provides a higher lift-to-drag ratio (L/D) than a typical entry capsule, but lower than a typical winged entry vehicle (such as the Space Shuttle Orbiter). A rigid Mid-L/D shape has advantages for large mass Mars EDL, including loads management, range capability during entry, and human spaceflight heritage. Previous large mass Mars studies have focused more on symmetric and/or circular cross-section Mid-L/D shapes such as the ellipsled. More recent work has shown performance advantages for non-circular cross section shapes. This paper will describe efforts to design a rigid Mid-L/D entry vehicle for Mars which shows mass and performance improvements over previous Mid-L/D studies. The proposed concept, work to date and evolution, forward path, and suggested future strategy are described.

  17. development of a new drag coefficient model for oil and gas

    African Journals Online (AJOL)

    eobe

    approximation of experimental data for e. R , from .... dynamic conditions in order to evaluate the drag and ... based on the experimental data for multiphase, water- oil-gas flow see ... Figure 6: Comparison of measured and model prediction.

  18. Experimental evaluation of the drag coefficient of water rockets by a simple free-fall test

    Energy Technology Data Exchange (ETDEWEB)

    Barrio-Perotti, R; Blanco-Marigorta, E; Argueelles-Diaz, K; Fernandez-Oro, J [Departamento de Energia, Universidad de Oviedo, Campus de Viesques, 33271 Gijon, Asturias (Spain)], E-mail: barrioraul@uniovi.es

    2009-09-15

    The flight trajectory of a water rocket can be reasonably calculated if the magnitude of the drag coefficient is known. The experimental determination of this coefficient with enough precision is usually quite difficult, but in this paper we propose a simple free-fall experiment for undergraduate students to reasonably estimate the drag coefficient of water rockets made from plastic soft drink bottles. The experiment is performed using relatively small fall distances (only about 14 m) in addition with a simple digital-sound-recording device. The fall time is inferred from the recorded signal with quite good precision, and it is subsequently introduced as an input of a Matlab (registered) program that estimates the magnitude of the drag coefficient. This procedure was tested first with a toy ball, obtaining a result with a deviation from the typical sphere value of only about 3%. For the particular water rocket used in the present investigation, a drag coefficient of 0.345 was estimated.

  19. Equations for calculating interfacial drag and shear from void fraction correlations

    International Nuclear Information System (INIS)

    Putney, J.M.

    1988-12-01

    Equations are developed for calculating interfacial drag and shear coefficients for dispersed vapour flows from void fraction correlations. The equations have a sound physical basis and lead to physically correct coefficients in all flow situations. (author)

  20. Wavelet Analysis on Turbulent Structure in Drag-Reducing Channel Flow Based on Direct Numerical Simulation

    Directory of Open Access Journals (Sweden)

    Xuan Wu

    2013-01-01

    Full Text Available Direct numerical simulation has been performed to study a polymer drag-reducing channel flow by using a discrete-element model. And then, wavelet analyses are employed to investigate the multiresolution characteristics of velocity components based on DNS data. Wavelet decomposition is applied to decompose velocity fluctuation time series into ten different frequency components including approximate component and detailed components, which show more regular intermittency and burst events in drag-reducing flow. The energy contribution, intermittent factor, and intermittent energy are calculated to investigate characteristics of different frequency components. The results indicate that energy contributions of different frequency components are redistributed by polymer additives. The energy contribution of streamwise approximate component in drag-reducing flow is up to 82%, much more than 25% in the Newtonian flow. Feature of turbulent multiscale structures is shown intuitively by continuous wavelet transform, verifying that turbulent structures become much more regular in drag-reducing flow.

  1. Turbulent skin-friction drag on a slender body of revolution and Gray's Paradox

    International Nuclear Information System (INIS)

    Nesteruk, Igor; Cartwright, Julyan H E

    2011-01-01

    The boundary layer on a slender body of revolution differs considerably from that on a flat plate, but these two cases can be connected by the Mangler-Stepanov transformations. The presented analysis shows that turbulent frictional drag on a slender rotationally symmetric body is much smaller than the flat-plate concept gives and the flow can remain laminar at larger Reynolds numbers. Both facts are valid for an unseparated flow pattern and enable us to revise the turbulent drag estimation of a dolphin, presented by Gray 74 years ago, and to resolve his paradox, since experimental data testify that dolphins can achieve flow without separation. The small values of turbulent skin-friction drag on slender bodies of revolution have additional interest for further experimental investigations and for applications of shapes without boundary-layer separation to diminish the total drag and noise of air- and hydrodynamic hulls.

  2. Drag reduction by natural polymeric additives in PMDS microchannel: Effect of types of additives

    Directory of Open Access Journals (Sweden)

    Ling Fiona W.M.

    2017-01-01

    Full Text Available Drag reduction technology was used in medical applications to enhance the blood flow in semiclogged blood streams which can be an alternative treatment for atherosclerosis. In this present study, natural polymeric drag reducing additives (DRA was introduced to replace synthetic polymer which has the possibility of bringing side effects to human health. Three different sources, namely okra, aloe vera and hibiscus were utilized to extract the natural polymeric additives which were then tested in custom made microchannel simulating human heart blood vessels. The performance of different types of additives was evaluated using pressure measurements. The maximum drag reduction up to 63.48% is achieved using 300 ppm of hibiscus mucilage at operating pressure of 50 mbar. In this present work, hibiscus showed the best drag reduction performance, giving the highest %FI in most of the cases. This experimental results proved that these natural polymeric additives could be utilized as DRA in enhancing the blood flow in semiclogged blood streams.

  3. In-situ measurement of electroosmotic drag coefficient in Nafion membrane for the PEMFC.

    Science.gov (United States)

    Peng, Zhe; Morin, Arnaud; Huguet, Patrice; Schott, Pascal; Pauchet, Joël

    2011-11-10

    A new method based on hydrogen pump has been developed to measure the electroosmotic drag coefficient in representative PEMFC operating conditions. It allows eliminating the back-flow of water which leads to some errors in the calculation of this coefficient with previously reported electrochemical methods. Measurements have been performed on 50 μm thick Nafion membranes both extruded and recast. Contrary to what has been described in most of previous published works, the electroosmotic drag coefficient decreases as the membrane water content increases. The same trend is observed for temperatures between 25 and 80 °C. For the same membrane water content, the electroosmotic drag coefficient increases with temperature. In the same condition, there is no difference in drag coefficient for extruded Nafion N112 and recast Nafion NRE212. These results are discussed on the basis of the two commonly accepted proton transport mechanisms, namely, Grotthus and vehicular.

  4. Pengaruh variasi lebar alur berbentuk segi empat pada permukaan silinder terhadap koefisien drag

    Directory of Open Access Journals (Sweden)

    Si Putu Gede Gunawan Tista

    2018-01-01

    Full Text Available Abstrak Kemajuan ilmu pengetahuan dan teknologi khususnya tentang ilmu mekanika fluida telah berkembang pesat.Ilmu mekanika fluida telah banyak memberikan kontribusi terhadap aspek kehidupan manusia, sebagai contoh adalah aliran fluida melintasi suatu silinder. Dalam aplikasi engineering banyak ditemukan peralatan menggunakan silinder seperti cerobong asap, tiang penyangga jembatan dan sebagainya. Peralatan-peralatan ini mengalami hembusan udara setiap saat sehingga kekuatan konstruksinya mengalami penurunan, hal ini disebabkan adanya drag yang arahnya searah aliran. Upaya yang dilakukan untuk mengurangi drag adalah dengan memanipulasi medan aliran. Manipulasi medan aliran dilakukan dengan membuat alur berbentuk segi empat pada permukaan silinder. Tujuan dari penelitian ini adalah menganalisa pengaruh variasi lebar alur berbentuk segi empat pada permukaan silinder terhadap koefisien drag. Penelitian ini dilakukan pada wind tunnel yang terdiri dari blower, pipa pitot, inclined manometer, U manometer, timbangan digital, dan silinder. Benda uji berupa silinder berdiameter 60 mm dan panjang 420 mm diletakkan vertikal di dalam wind tunnel. Lebar alur pada permukaan silinder divariasikan yaitu 3 mm, 4 mm, dan 5 mm. Pengujian distribusi tekanan diperoleh dengan mengukur tekanan permukaan silinder pada 36 titik dengan interval 10o. Pengujian gaya drag dilakukan dengan menggunakan timbangan digital yang mencatat besarnya massa, untuk mendapatkan gaya drag dikalikan dengan gravitasi. Hasil penelitian menunjukkan terjadi penurunan koefisien drag pada silinder beralur dibandingkan tanpa alur. Nilai koefisien terendah terjadi pada lebar alur 4 mm besarnya CD = 0,3734. Besarnya penurunan drag adalah 22,3 % dibandingkan tanpa alur. Kata kunci: pengurangan drag, lebar alur, alur segi empat, silinder Abstract Advances in science and technology, especially on the science of fluid mechanics has been growing. Science of fluid mechanics has contributed a lot of

  5. Pengaruh Variasi Jarak Penghalang Segitiga di depan Silinder Arah Vertikal terhadap Drag

    Directory of Open Access Journals (Sweden)

    I Putu Gede Gunawan Tista

    2018-04-01

    Full Text Available Salah satu cara untuk menghemat energi pada pesawat terbang dan bluff body lainnya adalah dengan mengurangi drag. Drag erat hubungannya dengan separasi aliran. Semakin awal terjadi separasi maka drag semakin meningkat. Oleh karena itu upaya yang dilakukan untuk mengurangi drag adalah dengan memanipulasi medan aliran fluida. Manipulasi aliran bisa dilakukan secara pasif antara lain menempelkan sebuah sirip pada bluff body, melubangi bluff body, menambahkan spiral pada bluff body dan menempatkan penghalang yang lebih kecil didepan bluff body. Penelitian ini yaitu dengan cara  menempatkan penghalang berbentuk segitiga didepan silinder. Dalam penelitian ini pengujian dilakukan pada wind tunnel, yang terdiri dari blower, pipa pitot, manometer, pipa silinder, dan segitiga penghalang. Penempatan penghalang divariasikan pada arah vertikal posisi y = 0, y = 5 mm, y = 10 mm, y = 15 mm, sedangkan posisi penghalang pada arah horisontal pada jarak  60 mm terhadap silinder dengan panjang sisi segitiga adalah 8 mm. Distribusi tekanan diperoleh dengan mengukur tekanan permukaan silinder pada 36 titik dengan interval 10o. Data yang diukur adalah tekanan permukaan silinder, tekanan statis, dan kecepatan aliran fluida. Hasil penelitian menunjukkan bahwa terjadi penurunan drag pada saat diberi penghalang segitiga dibandingkan dengan tanpa diberi penghalang segitiga. Nilai koefisien drag untuk silinder tanpa diberi penghalang yaitu 0.1276. Sedangkan dari variasi jarak penghalang pada arah vertikal diperoleh penurunan koefisien drag tertinggi adalah pada posisi  y = 0 yaitu sebesar 0,0186. Besarnya penurunan drag pada posisi ini adalah 85,45% dibandingkan dengan tanpa penghalang. One of the ways to reduce energy consumption an airplane and the other bluff body is by decreasing the drag.  The drag is closely related to the flow of separation. The early separation, then the drag will increase. Based on the fact the effort to decrease drag is conducted by

  6. A grid-independent EMMS/bubbling drag model for bubbling and turbulent fluidization

    DEFF Research Database (Denmark)

    Luo, Hao; Lu, Bona; Zhang, Jingyuan

    2017-01-01

    The EMMS/bubbling drag model takes the effects of meso-scale structures (i.e. bubbles) into modeling of drag coefficient and thus improves coarse-grid simulation of bubbling and turbulent fluidized beds. However, its dependence on grid size has not been fully investigated. In this article, we adopt...... a two-step scheme to extend the EMMS/bubbling model to the sub-grid level. Thus the heterogeneity index, HD, which accounts for the hydrodynamic disparity between homogeneous and heterogeneous fluidization, can be correlated as a function of both local voidage and slip velocity. Simulations over...... a periodic domain show the new drag model is less sensitive to grid size because of the additional dependence on local slip velocity. When applying the new drag model to simulations of realistic bubbling and turbulent fluidized beds, we find grid-independent results are easier to obtain for high...

  7. Variational and symplectic integrators for satellite relative orbit propagation including drag

    Science.gov (United States)

    Palacios, Leonel; Gurfil, Pini

    2018-04-01

    Orbit propagation algorithms for satellite relative motion relying on Runge-Kutta integrators are non-symplectic—a situation that leads to incorrect global behavior and degraded accuracy. Thus, attempts have been made to apply symplectic methods to integrate satellite relative motion. However, so far all these symplectic propagation schemes have not taken into account the effect of atmospheric drag. In this paper, drag-generalized symplectic and variational algorithms for satellite relative orbit propagation are developed in different reference frames, and numerical simulations with and without the effect of atmospheric drag are presented. It is also shown that high-order versions of the newly-developed variational and symplectic propagators are more accurate and are significantly faster than Runge-Kutta-based integrators, even in the presence of atmospheric drag.

  8. Drag of evaporating or condensing droplets in low Reynolds number flow

    International Nuclear Information System (INIS)

    Dukowicz, J.K.

    1984-01-01

    The steady-state drag of evaporating or condensing droplets in low Reynolds number flow is computed. Droplet drag in air is obtained for five representative liquids (water, methanol, benzene, heptane, octane) for a range of ambient temperatures, pressures, and vapor concentrations. The drag is in general increased for a condensing droplet, and decreased for an evaporating droplet. The changes in drag can be quite large and depend in detail on the degree of evaporation or condensation, and on the individual liquid and vapor properties. The present results are used to test the existing experimentally derived correlations of Eisenklam and Yuen and Chen in the low Reynolds number regime. The Yuen and Chen correlation is found to be quite successful, but only in the case of condensation or mild evaporation. An improved correlation is suggested for evaporating droplets

  9. Drag &Drop, Multiphysics & Neural Net-based Lab-on-Chip Optimization Software, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall objective of this project is to develop a drag and drop, component library (fluidic lego) based, system simulation and optimization software for entire...

  10. Drag &Drop, Mixed-Methodology-based Lab-on-Chip Design Optimization Software, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall objective is to develop a ?mixed-methodology?, drag and drop, component library (fluidic-lego)-based, system design and optimization tool for complex...

  11. A Limited Evaluation of Full Scale Control Surface Deflection Drag (Have FUN)

    National Research Council Canada - National Science Library

    Reinhardt, R. B; Celi, Sean A; Geraghty, Jeffrey T; Stahl, James W; Glover, Victor J; Bowman, Geoffrey G

    2007-01-01

    The Have FUN (FUll Scale Numbers) Test Management Project was conducted at the request of the USAF TPS as an investigation into the drag caused by control surface deflection during dynamic soaring techniques...

  12. Control of Nonlinear Coupled Electromagnetic Actuators for Active Drag Reduction in Turbulent Flow

    OpenAIRE

    Seidler, Florian; Trabert, Julius; Dück, Marcel; van Waasen, Stefan; Schiek, Michael; Abel, Dirk; Castelan, E. B.

    2016-01-01

    The research group FOR1779 “active drag reduction via wavy surface oscillations” develops robust methods for reduction of turbulent friction drag by flow control. The planned concentration on unsteady flow conditions requires a control of the electromagnetic actuator system for generation of transversal surface waves. The bars are positioned in parallel and coupled with an aluminum surface to generate a travelling wave perpendicular to the flow field. The actuator system can be approximately ...

  13. Evaluation of WRF Simulations With Different Selections of Subgrid Orographic Drag Over the Tibetan Plateau

    Science.gov (United States)

    Zhou, X.; Beljaars, A.; Wang, Y.; Huang, B.; Lin, C.; Chen, Y.; Wu, H.

    2017-09-01

    Weather Research and Forecasting (WRF) simulations with different selections of subgrid orographic drag over the Tibetan Plateau have been evaluated with observation and ERA-Interim reanalysis. Results show that the subgrid orographic drag schemes, especially the turbulent orographic form drag (TOFD) scheme, efficiently reduce the 10 m wind speed bias and RMS error with respect to station measurements. With the combination of gravity wave, flow blocking and TOFD schemes, wind speed is simulated more realistically than with the individual schemes only. Improvements are also seen in the 2 m air temperature and surface pressure. The gravity wave drag, flow blocking drag, and TOFD schemes combined have the smallest station mean bias (-2.05°C in 2 m air temperature and 1.27 hPa in surface pressure) and RMS error (3.59°C in 2 m air temperature and 2.37 hPa in surface pressure). Meanwhile, the TOFD scheme contributes more to the improvements than the gravity wave drag and flow blocking schemes. The improvements are more pronounced at low levels of the atmosphere than at high levels due to the stronger drag enhancement on the low-level flow. The reduced near-surface cold bias and high-pressure bias over the Tibetan Plateau are the result of changes in the low-level wind components associated with the geostrophic balance. The enhanced drag directly leads to weakened westerlies but also enhances the a-geostrophic flow in this case reducing (enhancing) the northerlies (southerlies), which bring more warm air across the Himalaya Mountain ranges from South Asia (bring less cold air from the north) to the interior Tibetan Plateau.

  14. The Locus of the apices of projectile trajectories under constant drag

    OpenAIRE

    Hernández-Saldaña, H.

    2017-01-01

    We present an analytical solution for the projectile coplanar motion under constant drag parametrised by the velocity angle. We found the locus formed by the apices of the projectile trajectories. The range and time of flight are obtained numerically and we find that the optimal launching angle is smaller than in the free drag case. This is a good example of problems with constant dissipation of energy that includes curvature, and it is proper for intermediate courses of mechanics.

  15. Drag reduction by natural polymeric additives in PMDS microchannel: Effect of types of additives

    OpenAIRE

    Ling Fiona W.M.; Abdulbari Hayder A.

    2017-01-01

    Drag reduction technology was used in medical applications to enhance the blood flow in semiclogged blood streams which can be an alternative treatment for atherosclerosis. In this present study, natural polymeric drag reducing additives (DRA) was introduced to replace synthetic polymer which has the possibility of bringing side effects to human health. Three different sources, namely okra, aloe vera and hibiscus were utilized to extract the natural polymeric additives which were then tested ...

  16. Influence of Blocker Distance Variations in form of Triangle in Front of Cylinder toward Drag Coefficien

    Directory of Open Access Journals (Sweden)

    Si Putu Gede Gunawan Tista

    2012-11-01

    Full Text Available One of the ways to reduce energy consumption on the air plane and the other bluff bodies are by decreasing the drag. Drag isclosely related to the flow separation. The earlier separation, then the drag will increase more. Based of the fact the effort todecrease drag is conducted by manipulating the field of fluid flow. Stream manipulation was be done by installing Triangleobstacle in front of cylinder. The purpose of this research is to analyze the effect of various distance triangle obstacle in front ofcylinder on drag. The present experiment was done by placing triangle rod in front of the cylinder. In the present research, theexperiment was conducted in the wind tunnel, which consisted of blower, pitot pipe, manometer, cylinder pipe, and triangle rod.The triangle was positioned at L/D = 1.19, L/D = 1.43, L/D = 1.67, L/D = 1.9, L/D = 2.14, L/D = 2.38, L/D = 2.62, and L/D =2.86 by upstream from the cylinder. The triangle was 8 mm uniform side. The Reynolds number based on the cylinder diameter (D= 42 mm was Re = 1.81 x 104. The research results showed that the triangle rod could decrease the drag of cylinder. Coefficientdrag for cylinder without triangle rod was 0.1276 while the biggest decrease of coefficient of drag with triangle rod washappened at L/D = 1.43 which was 0.0188. It means that the drag of cylinder with triangle rod was 85.25% lower than thecylinder alone.

  17. No Winglets: What a Drag...Argument for Adding Winglets to Large Air Force Aircraft

    Science.gov (United States)

    2008-01-01

    prices have once again brought improving aircraft aerodynamic efficiencies to the forefront of the energy conservation debate. Displaying how winglets ... winglet . Winglets are small, nearly vertical aerodynamic surfaces mounted on aircraft wingtips. Engineers design them with the same careful attention to...total drag.6 Since winglets , designed as small airfoils, reduce the aerodynamic drag associated with vortices by minimizing the amount of energy used

  18. Optimal control of lift/drag ratios on a rotating cylinder

    Science.gov (United States)

    Ou, Yuh-Roung; Burns, John A.

    1992-01-01

    We present the numerical solution to a problem of maximizing the lift to drag ratio by rotating a circular cylinder in a two-dimensional viscous incompressible flow. This problem is viewed as a test case for the newly developing theoretical and computational methods for control of fluid dynamic systems. We show that the time averaged lift to drag ratio for a fixed finite-time interval achieves its maximum value at an optimal rotation rate that depends on the time interval.

  19. Use of a pitot probe for determining wing section drag in flight

    Science.gov (United States)

    Saltzman, E. J.

    1975-01-01

    A wake traversing probe was used to obtain section drag and wake profile data from the wing of a sailplane. The transducer sensed total pressure defect in the wake as well as freestream total pressure on both sides of the sensing element when the probe moved beyond the wake. Profiles of wake total pressure defects plotted as a function of distance above and below the trailing edge plane were averaged for calculating section drag coefficients for flights at low dynamic pressures.

  20. Kevlar/PMR-15 reduced drag DC-9 reverser stang fairing

    Science.gov (United States)

    Kawai, R. T.

    1982-01-01

    A reduced drag fairing for the afterbody enclosing the thrust reverser actuators on the DC-9 has been developed with Kevlar-49/PMR-15 advanced composite material. The improved fairing reduces airplane drag 1% compared to the production baseline. Use of composites reduces weight 40% compared to an equivalent metal fairing. The Kevlar-49/PMR-15 advanced composite is an organic matrix material system that can be used at temperatures up to 500 F.

  1. Venus thermosphere and exosphere - First satellite drag measurements of an extraterrestrial atmosphere

    Science.gov (United States)

    Keating, G. M.; Tolson, R. H.; Hinson, E. W.

    1979-01-01

    Atmospheric drag measurements obtained from the study of the orbital decay of Pioneer Venus I indicate that atomic oxygen predominates in the Venus atmosphere above 160 kilometers. Drag measurements give evidence that conditions characteristic of a planetary thermosphere disappear near sundown, with inferred exospheric temperatures sharply dropping from approximately 300 K to less than 150 K. Observed densities are generally lower than given by theoretical models.

  2. Computational investigations of blunt body drag-reduction spikes in hypersonic flows

    International Nuclear Information System (INIS)

    Kamran, N.; Zahir, S.; Khan, M.A.

    2003-01-01

    Drag is an important parameter in the designing of high-speed vehicles. Such vehicles include hypervelocity projectiles, reentry modules, and hypersonic aircrafts. Therefore, there exists an active or passive technique to reduce drag due to the high pressures at nosetip region of the vehicle. Drag can be reduced by attaching a forward facing spike on the nose of the vehicle. The present study reviews and deals with the CFD analysis made on a standard blunt body to reduce aerodynamic drag due to the attachment of forward facing spikes for High-Speed vehicles. Different spike lengths have been examined to study the forebody flowfield. The investigation concludes that spikes are an effective way to reduce the aerodynamic drag due to reduced dynamic pressure on the nose caused by the separated flow on the spikes. With the accomplishment of confidence on computational data, study was extended in hypersonic Mach range with a drag prediction accuracy of ± 10%. In the present work, viscous fluid dynamics studies were performed for a complete freestream Mach number range of 5.0, 6.0, 7.0 and 8.0 for different spike lengths and zero degree angle of attack. (author)

  3. Experimental study on the minimum drag coefficient of supercritical pressure water in horizontal tubes

    International Nuclear Information System (INIS)

    Lei, Xianliang; Li, Huixiong; Guo, YuMeng; Zhang, Qing; Zhang, Weiqiang; Zhang, Qian

    2016-01-01

    Highlights: • The minimum drag coefficient phenomenon (MDC) has been observed and further investigated. • Effects of heat flux, mass flux and pressure to MDC have been discussed. • A series of comparisons between existing correlations and data have been conducted. • Two correlations of drag coefficient are proposed for isothermal and nonisothermal flow. - Abstract: Hydraulic resistance and its components are of great importance for understanding the turbulence nature of supercritical fluid and establishing prediction methods. Under supercritical pressures, the hydraulic resistance of the fluid exhibits a “pit” in the regions near its pseudo-critical point, which is hereafter called the minimum drag coefficient phenomenon. However, this special phenomenon was paid a little attention before. Hence systematical experiments have been carried out to investigate the hydraulic resistance of supercritical pressure water in both adiabatic and heated horizontal tubes. Parametric effects of heat flux, pressure and mass fluxes to drag coefficient are further compared. It is found that almost all of the existing correlations don’t agree well with the experimental data due to the insufficient consideration of thermal-properties near the pseudocritical point. Two correlations of the drag coefficients are finally proposed by introducing the new variable of the derivative of density with respect to temperature or Prandtl number, which can better predict the drag coefficient of isothermal and nonisothermal flow respectively.

  4. Analysis of Zero Reynolds Shear Stress Appearing in Dilute Surfactant Drag-Reducing Flow

    Directory of Open Access Journals (Sweden)

    Weiguo Gu

    2011-01-01

    Full Text Available Dilute surfactant solution of 25 ppm in the two-dimensional channel is investigated experimentally compared with water flow. Particle image velocimetry (PIV system is used to take 2D velocity frames in the streamwise and wall-normal plane. Based on the frames of instantaneous vectors and statistical results, the phenomenon of zero Reynolds shear stress appearing in the drag-reducing flow is discussed. It is found that 25 ppm CTAC solution exhibits the highest drag reduction at Re = 25000 and loses drag reduction completely at Re = 40000. When drag reduction lies in the highest, Reynolds shear stress disappears and reaches zero although the RMS of the velocity fluctuations is not zero. By the categorization in four quadrants, the fluctuations of 25 ppm CTAC solution are distributed in all four quadrants equally at Re = 25000, which indicates that turnaround transportation happens in drag-reducing flow besides Reynolds shear stress transportation. Moreover, the contour distribution of streamwise velocity and the fluctuations suggests that turbulence transportation is depressed in drag-reducing flow. The viscoelasticity is possible to decrease the turbulence transportation and cause the turnaround transportation.

  5. Gaze beats mouse

    DEFF Research Database (Denmark)

    Mateo, Julio C.; San Agustin, Javier; Hansen, John Paulin

    2008-01-01

    Facial EMG for selection is fast, easy and, combined with gaze pointing, it can provide completely hands-free interaction. In this pilot study, 5 participants performed a simple point-and-select task using mouse or gaze for pointing and a mouse button or a facial-EMG switch for selection. Gaze...

  6. Experimental investigation of shock wave diffraction over a single- or double-sphere model

    Science.gov (United States)

    Zhang, L. T.; Wang, T. H.; Hao, L. N.; Huang, B. Q.; Chen, W. J.; Shi, H. H.

    2017-01-01

    In this study, the unsteady drag produced by the interaction of a shock wave with a single- and a double-sphere model is measured using imbedded accelerometers. The shock wave is generated in a horizontal circular shock tube with an inner diameter of 200 mm. The effect of the shock Mach number and the dimensionless distance between spheres is investigated. The time-history of the drag coefficient is obtained based on Fast Fourier Transformation (FFT) band-block filtering and polynomial fitting of the measured acceleration. The measured peak values of the drag coefficient, with the associated uncertainty, are reported.

  7. A diagnostic model to estimate winds and small-scale drag from Mars Observer PMIRR data

    Science.gov (United States)

    Barnes, J. R.

    1993-01-01

    Theoretical and modeling studies indicate that small-scale drag due to breaking gravity waves is likely to be of considerable importance for the circulation in the middle atmospheric region (approximately 40-100 km altitude) on Mars. Recent earth-based spectroscopic observations have provided evidence for the existence of circulation features, in particular, a warm winter polar region, associated with gravity wave drag. Since the Mars Observer PMIRR experiment will obtain temperature profiles extending from the surface up to about 80 km altitude, it will be extensively sampling middle atmospheric regions in which gravity wave drag may play a dominant role. Estimating the drag then becomes crucial to the estimation of the atmospheric winds from the PMIRR-observed temperatures. An interative diagnostic model based upon one previously developed and tested with earth satellite temperature data will be applied to the PMIRR measurements to produce estimates of the small-scale zonal drag and three-dimensional wind fields in the Mars middle atmosphere. This model is based on the primitive equations, and can allow for time dependence (the time tendencies used may be based upon those computed in a Fast Fourier Mapping procedure). The small-scale zonal drag is estimated as the residual in the zonal momentum equation; the horizontal winds having first been estimated from the meridional momentum equation and the continuity equation. The scheme estimates the vertical motions from the thermodynamic equation, and thus needs estimates of the diabatic heating based upon the observed temperatures. The latter will be generated using a radiative model. It is hoped that the diagnostic scheme will be able to produce good estimates of the zonal gravity wave drag in the Mars middle atmosphere, estimates that can then be used in other diagnostic or assimilation efforts, as well as more theoretical studies.

  8. Riblet drag reduction in mild adverse pressure gradients: A numerical investigation

    International Nuclear Information System (INIS)

    Boomsma, Aaron; Sotiropoulos, Fotis

    2015-01-01

    Highlights: • We model several differently sized scalloped riblets using LES. • Riblets were modeled in both ZPG and mild APG and compared to each other and to a baseline (flat plate) case. • Scalloped riblets in the mild APG reduce drag only slightly more than those in ZPG. • Maximum values of streamwise turbulence intensities, streamwise vorticity, and TKE are proportional to riblet width. • Primary Reynolds shear stresses and turbulence energy production scale with riblet drag reduction. - Abstract: Riblet films are a passive method of turbulent boundary layer control that can reduce viscous drag. They have been studied with great detail for over 30 years. Although common riblet applications include flows with Adverse Pressure Gradients (APG), nearly all research thus far has been performed in channel flows. Recent research has provided motivation to study riblets in more complicated turbulent flows with claims that riblet drag reduction can double in mild APG common to airfoils at moderate angles of attack. Therefore, in this study, we compare drag reduction by scalloped riblet films between riblets in a zero pressure gradient and those in a mild APG using high-resolution large eddy simulations. In order to gain a fundamental understanding of the relationship between drag reduction and pressure gradient, we simulated several different riblet sizes that encompassed a broad range of s"+ (riblet width in wall units), similarly to many previously published experimental studies. We found that there was only a slight improvement in drag reduction for riblets in the mild APG. We also observed that peak values of streamwise turbulence intensity, turbulent kinetic energy, and streamwise vorticity scale with riblet width. Primary Reynolds shear stresses and turbulence kinetic energy production however scale with the ability of the riblet to reduce skin-friction.

  9. Investigation of Tractor Base Bleeding for Heavy Vehicle Aerodynamic Drag Reduction

    Energy Technology Data Exchange (ETDEWEB)

    Ortega, J; Salari, K; Storms, B

    2007-10-25

    One of the main contributors to the aerodynamic drag of a heavy vehicle is tractor-trailer gap drag, which arises when the vehicle operates within a crosswind. Under this operating condition, freestream flow is entrained into the tractor-trailer gap, imparting a momentum exchange to the vehicle and subsequently increasing the aerodynamic drag. While a number of add-on devices, including side extenders, splitter plates, vortex stabilizers, and gap sealers, have been previously tested to alleviate this source of drag, side extenders remain the primary add-on device of choice for reducing tractor-trailer gap drag. However, side extenders are not without maintenance and operational issues. When a heavy vehicle pivots sharply with respect to the trailer, as can occur during loading or unloading operations, the side extenders can become crushed against the trailer. Consequently, fleet operators are forced to incur additional costs to cover the repair or replacement of the damaged side extenders. This issue can be overcome by either shortening the side extenders or by devising an alternative drag reduction concept that can perform just as effectively as side extenders. To explore such a concept, we investigate tractor base bleeding as a means of reducing gap drag. Wind tunnel measurements are made on a 1:20 scale heavy vehicle model at a vehicle width-based Reynolds number of 420,000. The tractor bleeding flow, which is delivered through a porous material embedded within the tractor base, is introduced into the tractor-trailer gap at bleeding coefficients ranging from 0.0-0.018. To determine the performance of tractor base bleeding under more realistic operating conditions, computational fluid dynamics simulations are performed on a full-scale heavy vehicle within a crosswind for bleeding coefficients ranging from 0.0-0.13.

  10. Effects of biofouling development on drag forces of hull coatings for ocean-going ships: a review

    DEFF Research Database (Denmark)

    Lindholdt, Asger; Dam-Johansen, Kim; Olsen, S. M.

    2015-01-01

    This review presents a systematic overview of the literature and describes the experimental methods used to quantify the drag of hull coatings. It also summarizes the findings of hull coating's drag performance and identifies the main parameters impacting it. The advantages and disadvantages...... of the reported methods listed in this review provide an assessment of the most efficient methods to quantify the drag performance of hull coatings. This review determines that drag performance of hull coating technology varies depending on whether the coating condition is newly applied, after dynamic or static...... seawater exposure. The summarized data reveal that, while several methods have attempted to quantify drag performance of hull coatings, other methods must be explored in order to accurately measure the long-term drag performance of hull coatings in conditions mimicking those that ship hulls encounter...

  11. "It Has No Color, It Has No Gender, It's Gender Bending": Gender and Sexuality Fluidity and Subversiveness in Drag Performance.

    Science.gov (United States)

    Egner, Justine; Maloney, Patricia

    2016-07-01

    Gender identity is a key question for drag performers. Previous research has shown a lack of consensus about the subversiveness and gender fluidity of drag performers. This article examines the question: How does the relationship between performers and their audience affect the subversive nature and gender representation of drag performers in this study? Furthermore, is this relationship complicated by sexuality? This study uses ethnographic and interview methods, examining experiences of 10 drag performers. Findings indicate mutuality in the relationship between performers and audience. The recursiveness of this relationship provides a constant feedback to the performers in their effort to displace the audience's previously held notions. The performers have fluid understandings of gender and sexuality, often presenting multiple genders in and out of drag. Interactions between performers and their audience indicate their belief in gender fluidity; moreover, the drag performers themselves desire to be subversive and gender and sexually fluid.

  12. Turbulence and turbulent drag reduction in swirling flow: Inertial versus viscous forcing.

    Science.gov (United States)

    Burnishev, Yuri; Steinberg, Victor

    2015-08-01

    We report unexpected results of a drastic difference in the transition to fully developed turbulent and turbulent drag reduction (TDR) regimes and in their properties in a von Karman swirling flow with counter-rotating disks of water-based polymer solutions for viscous (by smooth disks) as well as inertial (by bladed disks) forcing and by tracking just torque Γ(t) and pressure p(t) . For the viscous forcing, just a single TDR regime is found with the transition values of the Reynolds number (Re) Re turb c =Re TDR c ≃(4.8±0.2)×10(5) independent of ϕ , whereas for the inertial forcing two turbulent regimes are revealed. The first transition is to fully developed turbulence, and the second one is to the TDR regime with both Re turb c and Re TDR c depending on polymer concentration ϕ . Both regimes differ by the values of C f and C p , by the scaling exponents of the fundamental turbulent characteristics, by the nonmonotonic dependencies of skewness and flatness of the pressure PDFs on Re, and by the different frequency power spectra of p with the different dependencies of the main vortex peak frequency in the p power spectra on ϕ and Re. Thus our experimental results show the transition to the TDR regime in a von Karman swirling flow for the viscous and inertial forcings in a sharp contrast to the recent experiments [Phys. Fluids 10, 426 (1998); Phys. Rev. E 47, R28(R) (1993); and J. Phys.: Condens. Matter 17, S1195 (2005)] where the transition to TDR is observed in the same swirling flow with counter-rotating disks only for the viscous forcing. The latter result has led its authors to the wrong conclusion that TDR is a solely boundary effect contrary to the inertial forcing associated with the bulk effect, and this conception is currently rather widely accepted in literature.

  13. Field-measured drag area is a key correlate of level cycling time trial performance

    Directory of Open Access Journals (Sweden)

    James E. Peterman

    2015-08-01

    Full Text Available Drag area (Ad is a primary factor determining aerodynamic resistance during level cycling and is therefore a key determinant of level time trial performance. However, Ad has traditionally been difficult to measure. Our purpose was to determine the value of adding field-measured Ad as a correlate of level cycling time trial performance. In the field, 19 male cyclists performed a level (22.1 km time trial. Separately, field-determined Ad and rolling resistance were calculated for subjects along with projected frontal area assessed directly (AP and indirectly (Est AP. Also, a graded exercise test was performed to determine $\\dot {V}{O}_{2}$V̇O2 peak, lactate threshold (LT, and economy. $\\dot {V}{O}_{2}$V̇O2 peak ($\\mathrm{l}~\\min ^{-1}$lmin−1 and power at LT were significantly correlated to power measured during the time trial (r = 0.83 and 0.69, respectively but were not significantly correlated to performance time (r = − 0.42 and −0.45. The correlation with performance time improved significantly (p < 0.05 when these variables were normalized to Ad. Of note, Ad alone was better correlated to performance time (r = 0.85, p < 0.001 than any combination of non-normalized physiological measure. The best correlate with performance time was field-measured power output during the time trial normalized to Ad (r = − 0.92. AP only accounted for 54% of the variability in Ad. Accordingly, the correlation to performance time was significantly lower using power normalized to AP (r = − 0.75 or Est AP (r = − 0.71. In conclusion, unless normalized to Ad, level time trial performance in the field was not highly correlated to common laboratory measures. Furthermore, our field-measured Ad is easy to determine and was the single best predictor of level time trial performance.

  14. Lift vs. drag based mechanisms for vertical force production in the smallest flying insects.

    Science.gov (United States)

    Jones, S K; Laurenza, R; Hedrick, T L; Griffith, B E; Miller, L A

    2015-11-07

    We used computational fluid dynamics to determine whether lift- or drag-based mechanisms generate the most vertical force in the flight of the smallest insects. These insects fly at Re on the order of 4-60 where viscous effects are significant. Detailed quantitative data on the wing kinematics of the smallest insects is not available, and as a result both drag- and lift-based strategies have been suggested as the mechanisms by which these insects stay aloft. We used the immersed boundary method to solve the fully-coupled fluid-structure interaction problem of a flexible wing immersed in a two-dimensional viscous fluid to compare three idealized hovering kinematics: a drag-based stroke in the vertical plane, a lift-based stroke in the horizontal plane, and a hybrid stroke on a tilted plane. Our results suggest that at higher Re, a lift-based strategy produces more vertical force than a drag-based strategy. At the Re pertinent to small insect hovering, however, there is little difference in performance between the two strategies. A drag-based mechanism of flight could produce more vertical force than a lift-based mechanism for insects at Re<5; however, we are unaware of active fliers at this scale. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Hydrodynamic interaction on large-Reynolds-number aligned bubbles: Drag effects

    International Nuclear Information System (INIS)

    Ramirez-Munoz, J.; Salinas-Rodriguez, E.; Soria, A.; Gama-Goicochea, A.

    2011-01-01

    Graphical abstract: Display Omitted Highlights: → The hydrodynamic interaction of a pair aligned equal-sized bubbles is analyzed. → The leading bubble wake decreases the drag on the trailing bubble. → A new semi-analytical model for the trailing bubble's drag is presented. → The equilibrium distance between bubbles is predicted. - Abstract: The hydrodynamic interaction of two equal-sized spherical gas bubbles rising along a vertical line with a Reynolds number (Re) between 50 and 200 is analyzed. An approach to estimate the trailing bubble drag based on the search of a proper reference fluid velocity is proposed. Our main result is a new, simple semi-analytical model for the trailing bubble drag. Additionally, the equilibrium separation distance between bubbles is predicted. The proposed models agree quantitatively up to small distances between bubbles, with reported data for 50 ≤ Re ≤ 200. The relative average error for the trailing bubble drag, Er, is found to be in the range 1.1 ≤ Er ≤ 1.7, i.e., it is of the same order of the analytical predictions in the literature.

  16. Hydrodynamic interaction on large-Reynolds-number aligned bubbles: Drag effects

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez-Munoz, J., E-mail: jrm@correo.azc.uam.mx [Departamento de Energia, Universidad Autonoma Metropolitana-Azcapotzalco, Av. San Pablo 180, Col. Reynosa Tamaulipas, 02200 Mexico D.F. (Mexico); Centro de Investigacion en Polimeros, Marcos Achar Lobaton No. 2, Tepexpan, 55885 Acolman, Edo. de Mexico (Mexico); Salinas-Rodriguez, E.; Soria, A. [Departamento de IPH, Universidad Autonoma Metropolitana-Iztapalapa, San Rafael Atlixco 186, Col. Vicentina, Iztapalapa, 09340 Mexico D.F. (Mexico); Gama-Goicochea, A. [Centro de Investigacion en Polimeros, Marcos Achar Lobaton No. 2, Tepexpan, 55885 Acolman, Edo. de Mexico (Mexico)

    2011-07-15

    Graphical abstract: Display Omitted Highlights: > The hydrodynamic interaction of a pair aligned equal-sized bubbles is analyzed. > The leading bubble wake decreases the drag on the trailing bubble. > A new semi-analytical model for the trailing bubble's drag is presented. > The equilibrium distance between bubbles is predicted. - Abstract: The hydrodynamic interaction of two equal-sized spherical gas bubbles rising along a vertical line with a Reynolds number (Re) between 50 and 200 is analyzed. An approach to estimate the trailing bubble drag based on the search of a proper reference fluid velocity is proposed. Our main result is a new, simple semi-analytical model for the trailing bubble drag. Additionally, the equilibrium separation distance between bubbles is predicted. The proposed models agree quantitatively up to small distances between bubbles, with reported data for 50 {<=} Re {<=} 200. The relative average error for the trailing bubble drag, Er, is found to be in the range 1.1 {<=} Er {<=} 1.7, i.e., it is of the same order of the analytical predictions in the literature.

  17. The drag and lift of different non-spherical particles from low to high Re

    Science.gov (United States)

    Sanjeevi, Sathish K. P.; Padding, Johan

    2017-11-01

    The present work investigates a simplified drag and lift model that can be used for different non-spherical particles. The flow around different non-spherical particles is studied using a multi-relaxation-time lattice Boltzmann method. We compute the mean drag coefficient CD , ϕ at different incident angles ϕ for a wide range of Reynolds numbers (Re). We show that the sine-squared drag law CD , ϕ =CD , ϕ =0° +(CD , ϕ =90° -CD , ϕ =0°) sin2 ϕ holds up to large Reynolds numbers Re = 2000 . The sine-squared dependence of CD occurs at Stokes flow (very low Re) due to linearity of the flow fields. We explore the physical origin behind the sine-squared law at high Re , and reveal that surprisingly, this does not occur due to linearity of flow fields. Instead, it occurs due to an interesting pattern of pressure distribution contributing to the drag, at higher Re , for different incident angles. Similarly, we find that the equivalent theoretical equation of lift coefficient CL can provide a decent approximation, even at high Re , for elongated particles. Such a drag and lift law valid at high Re is very much useful for Euler-Lagrangian fluidization simulations of the non-spherical particles. European Research Council (ERC) consolidator Grant scheme, Contract No. 615096 (NonSphereFlow).

  18. Can large-scale oblique undulations on a solid wall reduce the turbulent drag?

    Science.gov (United States)

    Ghebali, Sacha; Chernyshenko, Sergei I.; Leschziner, Michael A.

    2017-10-01

    Direct numerical simulations of fully developed turbulent channel flows with wavy walls are undertaken. The wavy walls, skewed with respect to the mean flow direction, are introduced as a means of emulating a Spatial Stokes Layer (SSL) induced by in-plane wall motion. The transverse shear strain above the wavy wall is shown to be similar to that of a SSL, thereby affecting the turbulent flow and leading to a reduction in the turbulent skin-friction drag. However, some important differences with respect to the SSL case are brought to light too. In particular, the phase variations of the turbulent properties are accentuated and, unlike in the SSL case, there is a region of increased turbulence production over a portion of the wall, above the leeward side of the wave, thus giving rise to a local increase in dissipation. The pressure- and friction-drag levels are carefully quantified for various flow configurations, exhibiting a combined maximum overall-drag reduction of about 0.6%. The friction-drag reduction is shown to behave approximately quadratically for small wave slopes and then linearly for higher slopes, whilst the pressure-drag penalty increases quadratically. The transverse shear-strain layer is shown to be approximately Reynolds-number independent when the wave geometry is scaled in wall units.

  19. Observation and Numerical Experiments for Drag Coefficient Under Typhoon Wind Forcing

    Institute of Scientific and Technical Information of China (English)

    CAO Huiqiu; ZHOU Liangming; LI Shuiqing; WANG Zhifeng

    2017-01-01

    This paper presents a study on drag coefficients under typhoon wind forcing based on observations and numerical experiments.The friction velocity and wind speed are measured at a marine observation platform in the South China Sea.Three typhoons:SOULIK (2013),TRAMI (2013) and FITOW (2013) are observed at a buoy station in the northeast sea area of Pingtan Island.A new parameterization is formulated for the wind drag coefficient as a function of wind speed.It is found that the drag coefficient (Ca) increases linearly with the slope of 0.083× 10-3 for wind speed less than 24 m s-1.To investigate the drag coefficient under higher wind conditions,three numerical experiments are implemented for these three typhoons using SWAN wave model.The wind input data are objective reanalysis datasets,which are assimilated with many sources and provided every six hours with the resolution of 0.125° ×0.125°.The numerical simulation results show a good agreement with wave observation data under typhoon wind forcing.The results indicate that the drag coefficient levels off with the linear slope of 0.012× 10-3 for higher wind speeds (less than 34 m s-1) and the new parameterization improvese the simulation accuracy compared with the Wu (1982) default used in SWAN.

  20. Wake-Model Effects on Induced Drag Prediction of Staggered Boxwings

    Directory of Open Access Journals (Sweden)

    Julian Schirra

    2018-01-01

    Full Text Available For staggered boxwings the predictions of induced drag that rely on common potential-flow methods can be of limited accuracy. For example, linear, freestream-fixed wake models cannot resolve effects related to wake deflection and roll-up, which can have significant affects on the induced drag projection of these systems. The present work investigates the principle impact of wake modelling on the accuracy of induced drag prediction of boxwings with stagger. The study compares induced drag predictions of a higher-order potential-flow method that uses fixed and relaxed-wake models, and of an Euler-flow method. Positive-staggered systems at positive angles of attack are found to be particularly prone to higher-order wake effects due to vertical contraction of wakes trajectories, which results in smaller effective height-to-span ratios than compared with negative stagger and thus closer interactions between trailing wakes and lifting surfaces. Therefore, when trying to predict induced drag of positive staggered boxwings, only a potential-flow method with a fully relaxed-wake model will provide the high-degree of accuracy that rivals that of an Euler method while being computationally significantly more efficient.

  1. Drag crisis moderation by thin air layers sustained on superhydrophobic spheres falling in water

    KAUST Repository

    Jetly, Aditya

    2018-01-22

    We investigate the effect of thin air layers naturally sustained on superhydrophobic surfaces on the terminal velocity and drag force of metallic spheres free falling in water. The surface of 20 mm to 60 mm steel or tungsten-carbide spheres is rendered superhydrophobic by a simple coating process that uses commercially available hydrophobic agent. By comparing the free fall of unmodified spheres and superhydrophobic spheres in a 2.5 meters tall water tank, It is demonstrated that even a very thin air layer (~ 1 – 2 μm) that covers the freshly dipped superhydrophobic sphere, can reduce the drag force on the spheres by up to 80 %, at Reynolds numbers 105 - 3×105 , owing to an early drag crisis transition. This study complements prior investigations on the drag reduction efficiency of model gas layers sustained on heated metal spheres falling in liquid by the Leidenfrost effect. The drag reduction effects are expected to have significant implication for the development of sustainable air-layer-based energy saving technologies.

  2. Drag and diffusion of heavy quarks in a hot and anisotropic QCD medium

    International Nuclear Information System (INIS)

    Srivastava, P.K.; Patra, Binoy Krishna

    2017-01-01

    The propagation of heavy quarks (HQs) in a medium was quite often modeled by the Fokker-Planck (FP) equation. Since the transport coefficients, related to drag and diffusion processes, are the main ingredients in the FP equation, the evolution of HQs is thus effectively controlled by them. At the initial stage of the relativistic heavy-ion collisions, asymptotic weak-coupling causes the free-streaming motions of partons in the beam direction and the expansions in transverse directions are almost frozen, hence an anisotropy in the momentum space sets in. Since HQs are too produced in the same time, the study of the effect of momentum anisotropy on the drag and diffusion coefficients becomes highly desirable. In this article we have thus studied the drag and diffusion of HQs in the anisotropic medium and found that the presence of the anisotropy reduces both drag and diffusion coefficients. In addition, the anisotropy introduces an angular dependence to both the drag and diffusion coefficients, as a result both coefficients get more inflated when the partons are moving transversely to the direction of anisotropy than when moving parallel to the direction of anisotropy. (orig.)

  3. Drag and diffusion of heavy quarks in a hot and anisotropic QCD medium

    Energy Technology Data Exchange (ETDEWEB)

    Srivastava, P.K.; Patra, Binoy Krishna [Indian Institute of Technology Roorkee, Department of Physics, Roorkee (India)

    2017-06-15

    The propagation of heavy quarks (HQs) in a medium was quite often modeled by the Fokker-Planck (FP) equation. Since the transport coefficients, related to drag and diffusion processes, are the main ingredients in the FP equation, the evolution of HQs is thus effectively controlled by them. At the initial stage of the relativistic heavy-ion collisions, asymptotic weak-coupling causes the free-streaming motions of partons in the beam direction and the expansions in transverse directions are almost frozen, hence an anisotropy in the momentum space sets in. Since HQs are too produced in the same time, the study of the effect of momentum anisotropy on the drag and diffusion coefficients becomes highly desirable. In this article we have thus studied the drag and diffusion of HQs in the anisotropic medium and found that the presence of the anisotropy reduces both drag and diffusion coefficients. In addition, the anisotropy introduces an angular dependence to both the drag and diffusion coefficients, as a result both coefficients get more inflated when the partons are moving transversely to the direction of anisotropy than when moving parallel to the direction of anisotropy. (orig.)

  4. Experimental and Numerical Study of Water Entry Supercavity Influenced by Turbulent Drag-Reducing Additives

    Directory of Open Access Journals (Sweden)

    Chen-Xing Jiang

    2014-04-01

    Full Text Available The configurational and dynamic characteristics of water entry supercavities influenced by turbulent drag-reducing additives were studied through supercavitating projectile approach, experimentally and numerically. The projectile was projected vertically into water and aqueous solution of CTAC with weight concentrations of 100, 500, and 1000 ppm, respectively, using a pneumatic nail gun. The trajectories of the projectile and the supercavity configuration were recorded by a high-speed CCD camera. Besides, water entry supercavities in water and CTAC solution were numerically simulated based on unsteady RANS scheme, together with application of VOF multiphase model. The Cross viscosity model was adopted to represent the fluid property of CTAC solution. It was obtained that the numerical simulation results are in consistence with experimental data. Numerical and experimental results all show that the length and diameter of supercavity in drag-reducing solution are larger than those in water, and the drag coefficient is smaller than that in water; the maintaining time of supercavity is longer in solution as well. The surface tension plays an important role in maintaining the cavity. Turbulent drag-reducing additives have the potential in enhancement of supercavitation and drag reduction.

  5. Electro—magnetic control of shear flow over a cylinder for drag reduction and lift enhancement

    International Nuclear Information System (INIS)

    Zhang Hui; Fan Bao-Chun; Chen Zhi-Hua; Chen Shuai; Li Hong-Zhi

    2013-01-01

    In this paper, the electro—magnetic control of a cylinder wake in shear flow is investigated numerically. The effects of the shear rate and Lorentz force on the cylinder wake, the distribution of hydrodynamic force, and the drag/lift phase diagram are discussed in detail. It is revealed that Lorentz force can be classified into the field Lorentz force and the wall Lorentz force and they affect the drag and lift forces independently. The drag/lift phase diagram with a shape of ''8'' consists of two closed curves, which correspond to the halves of the shedding cycle dominated by the upper and lower vortices respectively. The free stream shear (K > 0) induces the diagram to move downward and leftward, so that the average lift force directs toward the downside. With the upper Lorentz force, the diagram moves downwards and to the right by the field Lorentz force, thus resulting in the drag increase and the lift reduction, whereas it moves upward and to the left by the wall Lorentz force, leading to the drag reduction and the lift increase. Finally the diagram is dominated by the wall Lorentz force, thus moving upward and leftward. Therefore the upper Lorentz force, which enhances the lift force, can be used to overcome the lift loss due to the free stream shear, which is also obtained in the experiment. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  6. Fluid drag reduction and efficient self-cleaning with rice leaf and butterfly wing bioinspired surfaces

    Science.gov (United States)

    Bixler, Gregory D.; Bhushan, Bharat

    2013-08-01

    Researchers are continually inspired by living nature to solve complex challenges. For example, unique surface characteristics of rice leaves and butterfly wings combine the shark skin (anisotropic flow leading to low drag) and lotus leaf (superhydrophobic and self-cleaning) effects, producing the so-called rice and butterfly wing effect. In this paper, we present an overview of rice leaf and butterfly wing fluid drag and self-cleaning studies. In addition, we examine two other promising aquatic surfaces in nature known for such properties, including fish scales and shark skin. Morphology, drag, self-cleaning, contact angle, and contact angle hysteresis data are presented to understand the role of wettability, viscosity, and velocity. Liquid repellent coatings are utilized to recreate or combine various effects. Discussion is provided along with conceptual models describing the role of surface structures related to low drag, self-cleaning, and antifouling properties. Modeling provides design guidance when developing novel low drag and self-cleaning surfaces for applications in the medical, marine, and industrial fields.

  7. Mouse Genome Informatics (MGI)

    Data.gov (United States)

    U.S. Department of Health & Human Services — MGI is the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data to facilitate the study of human...

  8. Mouse Phenome Database (MPD)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Mouse Phenome Database (MPD) has characterizations of hundreds of strains of laboratory mice to facilitate translational discoveries and to assist in selection...

  9. Disturbance of eelgrass Zostera marina by commercial mussel Mytilus edulis harvesting in Maine: Dragging impacts and habitat recovery

    Science.gov (United States)

    Neckles, Hilary A.; Short, Frederick T.; Barker, Seth; Kopp, Blaine S.

    2005-01-01

    We studied the effects of commercial harvest of blue mussels Mytilus edulis on eelgrass Zostera marina L. in Maquoit Bay, Maine, USA, at a hierarchy of scales. We used aerial photography, underwater video, and eelgrass population- and shoot-based measurements to quantify dragging impacts within 4 sites that had been disturbed at different times over an approximate 7 yr interval, and to project eelgrass meadow recovery rates. Dragging had disturbed 10% of the eelgrass cover in Maquoit Bay, with dragged sites ranging from 3.4 to 31.8 ha in size. Dragging removed above- and belowground plant material from the majority of the bottom in the disturbed sites. One year following dragging, eelgrass shoot density, shoot height and total biomass of disturbed sites averaged respectively 2 to 3%, 46 to 61% and model based on measured rates of lateral patch-expansion (mean 12.5 cm yr-1) and new-patch recruitment (mean 0.19 patches m-2 yr-1) yielded a mean bed recovery time of 9 to 11 yr following dragging, depending on initial degree of plant removal. Model simulations suggested that with favorable environmental conditions, eelgrass beds might recover from dragging disturbance in 6 yr; conversely, recovery under conditions less conducive to eelgrass growth could require 20 yr or longer. This study shows that mussel dragging poses a severe threat to eelgrass in this region and that regulations to protect eelgrass from dragging impacts would maintain the integrity of a substantial amount of habitat.

  10. Drag-reducing performance of obliquely aligned superhydrophobic surface in turbulent channel flow

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Sho; Fukagata, Koji [Department of Mechanical Engineering, Keio University, Hiyoshi 3-14-1, Kohoku-ku, Yokohama 223-8522 (Japan); Mamori, Hiroya, E-mail: fukagata@mech.keio.ac.jp [Department of Mechanical Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika-ku, Tokyo 125-8585 (Japan)

    2017-04-15

    Friction drag reduction effect by superhydrophobic surfaces in a turbulent channel flow is investigated by means of direct numerical simulation. The simulations are performed under a constant pressure gradient at the friction Reynolds number of 180. A special focus is laid upon the influence of the angle of microridge structure to flow direction, while the gas area fraction on the surface is kept at 50% and the groove width is kept constant at 33.75 wall units. Larger drag reduction effect is observed for a smaller angle: the bulk-mean velocity is increased about 15% when the microridge is parallel to the flow. The drag reduction effect is found to deteriorate rapidly with the microridge angle due to a decrease in the slip velocity. The Reynolds stress budgets show that the modification in each physical effect is qualitatively similar but more pronounced when the microridge is aligned with the stream. (paper)

  11. Heavy Class Helicopter Fuselage Model Drag Reduction by Active Flow Control Systems

    Science.gov (United States)

    De Gregorio, F.

    2017-08-01

    A comprehensive experimental investigation of helicopter blunt fuselage drag reduction using active flow control is being carried out within the European Clean Sky program. The objective is to demonstrate the capability of several active flow technologies to decrease fuselage drag by alleviating the flow separation occurring in the rear area of some helicopters. The work is performed on a simplified blunt fuselage at model-scale. Two different flow control actuators are considered for evaluation: steady blowing, unsteady blowing (or pulsed jets). Laboratory tests of each individual actuator are first performed to assess their performance and properties. The fuselage model is then equipped with these actuators distributed in 3 slots located on the ramp bottom edge. This paper addresses the promising results obtained during the wind-tunnel campaign, since significant drag reductions are achieved for a wide range of fuselage angles of attack and yaw angles without detriment of the other aerodynamic characteristics.

  12. Buoyancy increase and drag-reduction through a simple superhydrophobic coating.

    Science.gov (United States)

    Hwang, Gi Byoung; Patir, Adnan; Page, Kristopher; Lu, Yao; Allan, Elaine; Parkin, Ivan P

    2017-06-08

    A superhydrophobic paint was fabricated using 1H,1H,2H,2H-perfluorooctyltriethoxysilane (PFOTES), TiO 2 nanoparticles and ethanol. The paint has potential for aquatic application of a superhydrophobic coating as it induces increased buoyancy and drag reduction. Buoyance testing showed that the reduction of surface energy by superhydrophobic coating made it feasible that glass, a high density material, was supported by the surface tension of water. In a miniature boat sailing test, it was shown that the low energy surface treatment decreased the adhesion of water molecules to the surface of the boat resulting in a reduction of the drag force. Additionally, a robust superhydrophobic surface was fabricated through layer-by-layer coating using adhesive double side tape and the paint, and after a 100 cm abrasion test with sand paper, the surface still retained its water repellency, enhanced buoyancy and drag reduction.

  13. Mechanics of load-drag-unload contact cleaning of gecko-inspired fibrillar adhesives.

    Science.gov (United States)

    Abusomwan, Uyiosa A; Sitti, Metin

    2014-10-14

    Contact self-cleaning of gecko-inspired synthetic adhesives with mushroom-shaped tips has been demonstrated recently using load-drag-unload cleaning procedures similar to that of the natural animal. However, the underlying mechanics of contact cleaning has yet to be fully understood. In this work, we present a detailed experiment of contact self-cleaning that shows that rolling is the dominant mechanism of cleaning for spherical microparticle contaminants, during the load-drag-unload procedure. We also study the effect of dragging rate and normal load on the particle rolling friction. A model of spherical particle rolling on an elastomer fibrillar adhesive interface is developed and agrees well with the experimental results. This study takes us closer to determining design parameters for achieving self-cleaning fibrillar adhesives.

  14. Satellite drag effects due to uplifted oxygen neutrals during super magnetic storms

    Science.gov (United States)

    Lakhina, Gurbax S.; Tsurutani, Bruce T.

    2017-12-01

    During intense magnetic storms, prompt penetration electric fields (PPEFs) through E × B forces near the magnetic equator uplift the dayside ionosphere. This effect has been called the dayside super-fountain effect. Ion-neutral drag forces between the upward moving O+ (oxygen ions) and oxygen neutrals will elevate the oxygen atoms to higher altitudes. This paper gives a linear calculation indicating how serious the effect may be during an 1859-type (Carrington) superstorm. It is concluded that the oxygen neutral densities produced at low-Earth-orbiting (LEO) satellite altitudes may be sufficiently high to present severe satellite drag. It is estimated that with a prompt penetrating electric field of ˜ 20 mV m-1 turned on for 20 min, the O atoms and O+ ions are uplifted to 850 km where they produce about 40-times-greater satellite drag per unit mass than normal. Stronger electric fields will presumably lead to greater uplifted mass.

  15. Simple interphase drag model for numerical two-fluid modeling of two-phase flow systems

    International Nuclear Information System (INIS)

    Chow, H.; Ransom, V.H.

    1984-01-01

    The interphase drag model that has been developed for RELAP5/MOD2 is based on a simple formulation having flow regime maps for both horizontal and vertical flows. The model is based on a conventional semi-empirical formulation that includes the product of drag coefficient, interfacial area, and relative dynamic pressure. The interphase drag model is implemented in the RELAP5/MOD2 light water reactor transient analysis code and has been used to simulate a variety of separate effects experiments to assess the model accuracy. The results from three of these simulations, the General Electric Company small vessel blowdown experiment, Dukler and Smith's counter-current flow experiment, and a Westinghouse Electric Company FLECHT-SEASET forced reflood experiment, are presented and discussed

  16. Coulomb drag in electron-hole bilayer: Mass-asymmetry and exchange correlation effects

    Science.gov (United States)

    Arora, Priya; Singh, Gurvinder; Moudgil, R. K.

    2018-04-01

    Motivated by a recent experiment by Zheng et al. [App. Phys. Lett. 108, 062102 (2016)] on coulomb drag in electron-hole and hole-hole bilayers based on GaAs/AlGaAs semiconductor heterostructure, we investigate theoretically the influence of mass-asymmetry and temperature-dependence of correlations on the drag rate. The correlation effects are dealt with using the Vignale-Singwi effective inter-layer interaction model which includes correlations through local-field corrections to the bare coulomb interactions. However, in this work, we have incorporated only the intra-layer correlations using the temperature-dependent Hubbard approximation. Our results display a reasonably good agreement with the experimental data. However, it is crucial to include both the electron-hole mass-asymmetry and temperature-dependence of correlations. Mass-asymmetry and correlations are found to result in a substantial enhancement of drag resistivity.

  17. Pengaruh variasi jarak antar ring berbentuk segi empat pada permukaan silinder terhadap koefisien drag

    Directory of Open Access Journals (Sweden)

    Si Putu Gede Gunawan Tista

    2016-12-01

    Full Text Available Abstrak: Dalam aplikasi engineering banyak ditemukan peralatan yang menggunakan silinder seperti tiang penyangga jembatan,cerobong asap, tiang pancang pengeboran minyak lepas pantai dan sebagainya. Peralatan-peralatan tersebutmengalami hembusan udara setiap saat, yang menyebabkan kekuatan konstruksinya berkurang, akibat adanya drag.Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi jarak antar ring berbentuk segi empat padapermukaan silinder terhadap koefisien drag. Penelitian ini dilakukan pada wind tunnel (lorong udara yang terdiri dariblower (untuk menghembuskan udara, pipa pitot, U tube manometer, inclined manometer, neraca digital, silinderdengan ring segi empat. Pada penelitian ini, dilakukan dengan memvariasikan Jarak antar ring yaitu 30 mm, 40 mm, 50mm, 60 mm dan 70 mm. Silinder diletakkan vertikal dalam wind tunnel dengan diameter D = 60 mm. Gaya dragdiperoleh dengan menggunakan neraca digital yang mencatat besarnya massa, kemudian dikalikan dengan percepatangravitasi. Distribusi tekanan diperoleh dengan mengukur tekanan pada permukaan silinder menggunakan inclinedmanometer pada 36 titik dengan interval 10o. Hasil penelitian menunjukkan semakin besar jarak antar ring koefisiendrag semakin besar. Koefisien Drag terendah terjadi pada jarak antar ring L = 30 mm atau L/D = 0.50, besarnya CD =0,606352. Besarnya penurunan drag dibandingkan tanpa ring adalah 29,3 %.Kata kunci: Silinder, ring segi empat, jarak antar ring, koefisien drag Abstract: In many engineering applications there are many types of equipment that use cylinders, such as smoke chimney, bridgesupport column, etc. The equipment is undergoing drag due to the airflow that flows through it. The existence of the dragwill reduce its lifetime. One of the efforts to reduce drag is to create a rectangular ring on the surface of the cylinder. Thepurpose of this study was to determine the effect of variations in the distance between the ring of a rectangular ring onthe

  18. Effect of Phonon Drag on the Thermopower in a Parabolic Quantum Well

    Energy Technology Data Exchange (ETDEWEB)

    Hasanov, Kh. A., E-mail: xanlarhasanli@rambler.ru; Huseynov, J. I. [Azerbaijan State Pedagogical University (Azerbaijan); Dadashova, V. V. [Baku State University (Azerbaijan); Aliyev, F. F. [National Academy of Sciences of Azerbaijan, Abdullaev Institute of Physics (Azerbaijan)

    2016-03-15

    The theory of phonon-drag thermopower resulting from a temperature gradient in the plane of a two-dimensional electron gas layer in a parabolic quantum well is developed. The interaction mechanisms between electrons and acoustic phonons are considered, taking into account potential screening of the interaction. It is found that the effect of electron drag by phonons makes a significant contribution to the thermopower of the two-dimensional electron gas. It is shown that the consideration of screening has a significant effect on the drag thermopower. For the temperature dependence of the thermopower in a parabolic GaAs/AlGaAs quantum well in the temperature range of 1–10 K, good agreement between the obtained theoretical results and experiments is shown.

  19. Hydrodynamic flows of non-Fermi liquids: Magnetotransport and bilayer drag

    Science.gov (United States)

    Patel, Aavishkar A.; Davison, Richard A.; Levchenko, Alex

    2017-11-01

    We consider a hydrodynamic description of transport for generic two-dimensional electron systems that lack Galilean invariance and do not fall into the category of Fermi liquids. We study magnetoresistance and show that it is governed only by the electronic viscosity provided that the wavelength of the underlying disorder potential is large compared to the microscopic equilibration length. We also derive the Coulomb drag transresistance for double-layer non-Fermi-liquid systems in the hydrodynamic regime. As an example, we consider frictional drag between two quantum Hall states with half-filled lowest Landau levels, each described by a Fermi surface of composite fermions coupled to a U (1 ) gauge field. We contrast our results to prior calculations of drag of Chern-Simons composite particles and place our findings in the context of available experimental data.

  20. CFD Study of Drag and Lift of Sepak Takraw Ball at Different Face Orientations

    Directory of Open Access Journals (Sweden)

    Abdul Syakir Abdul Mubin

    2015-01-01

    Full Text Available There have been a significant number of researches on computational fluid dynamic (CFD analysis of balls used in sports such as golf balls, tennis balls, and soccer balls. Sepak takraw is a high speed court game predominantly played in Southeast Asia using mainly the legs and head. The sepak takraw ball is unique because it is not enclosed and made of woven plastic. Hence a study of its aerodynamicswould give insight into its behaviour under different conditions of play. In this study the dynamics of the fluid around a static sepak takraw ball was investigated at different wind speeds for three different orientations using CFD. It was found that although the drag did not differ very much, increasing the wind velocity causes an increase in drag. The lift coefficientvaries as the velocity increases and does not show a regular pattern. The drag and lift coefficients are influenced by the orientation of the sepak takraw ball.

  1. Development of a Kevlar/PMR-15 reduced drag DC-9 nacelle fairing

    Science.gov (United States)

    Kawai, R. T.; Hrach, F. J.

    1980-01-01

    The paper describes an advanced composite fairing designed to reduce drag on DC-9 nacelles as a part of the NASA Engine Component Improvement Program. This fairing is the aft enclosure for the thrust reverser actuator system on JT8D engine nacelles and is subjected to a 500 F exhaust flow during the reverse thrust. A reduced-drag configuration was developed by using in-flight tuft surveys for flow visualization in order to identify areas with low-quality flow, and then modifying the aerodynamic lines to improve the flow. A fabrication method for molding the part in an autoclave was developed; this material system is suitable for 500 F. The resultant composite fairing reduces the overall aircraft drag 1% with a weight reduction of 40% when compared with a metal component.

  2. Effect of plasma actuator and splitter plate on drag coefficient of a circular cylinder

    Science.gov (United States)

    Akbıyık, Hürrem; Erkan Akansu, Yahya; Yavuz, Hakan; Ertuğrul Bay, Ahmet

    2016-03-01

    In this paper, an experimental study on flow control around a circular cylinder with splitter plate and plasma actuator is investigated. The study is performed in wind tunnel for Reynolds numbers at 4000 and 8000. The wake region of circular cylinder with a splitter plate is analyzed at different angles between 0 and 180 degrees. In this the study, not only plasma actuators are activated but also splitter plate is placed behind the cylinder. A couple electrodes are mounted on circular cylinder at ±90 degrees. Also, flow visualization is achieved by using smoke wire method. Drag coefficient of the circular cylinder with splitter plate and the plasma actuator are obtained for different angles and compared with the plain circular cylinder. While attack angle is 0 degree, drag coefficient is decreased about 20% by using the splitter plate behind the circular cylinder. However, when the plasma actuators are activated, the improvement of the drag reduction is measured to be 50%.

  3. Drag reduction using wrinkled surfaces in high Reynolds number laminar boundary layer flows

    Science.gov (United States)

    Raayai-Ardakani, Shabnam; McKinley, Gareth H.

    2017-09-01

    Inspired by the design of the ribbed structure of shark skin, passive drag reduction methods using stream-wise riblet surfaces have previously been developed and tested over a wide range of flow conditions. Such textures aligned in the flow direction have been shown to be able to reduce skin friction drag by 4%-8%. Here, we explore the effects of periodic sinusoidal riblet surfaces aligned in the flow direction (also known as a "wrinkled" texture) on the evolution of a laminar boundary layer flow. Using numerical analysis with the open source Computational Fluid Dynamics solver OpenFOAM, boundary layer flow over sinusoidal wrinkled plates with a range of wavelength to plate length ratios ( λ / L ), aspect ratios ( 2 A / λ ), and inlet velocities are examined. It is shown that in the laminar boundary layer regime, the riblets are able to retard the viscous flow inside the grooves creating a cushion of stagnant fluid that the high-speed fluid above can partially slide over, thus reducing the shear stress inside the grooves and the total integrated viscous drag force on the plate. Additionally, we explore how the boundary layer thickness, local average shear stress distribution, and total drag force on the wrinkled plate vary with the aspect ratio of the riblets as well as the length of the plate. We show that riblets with an aspect ratio of close to unity lead to the highest reduction in the total drag, and that because of the interplay between the local stress distribution on the plate and stream-wise evolution of the boundary layer the plate has to exceed a critical length to give a net decrease in the total drag force.

  4. Communication Webagogy 2.0: More Click, Less Drag.

    Science.gov (United States)

    Radford, Marie L.; Wagner, Kurt W.

    2000-01-01

    Argues that, because of the chaotic nature of the Web and the competing searching software, no single search tool will suffice. Lists and discusses meta search engines; communication meta-sites and subject directories, all indexed by humans; teaching resources for communication courses that utilize the unique features of the Web; and web sites…

  5. Drag resistance measurements for newly applied antifouling coatings and welding seams on ship hull surface

    DEFF Research Database (Denmark)

    Wang, Xueting; Olsen, S. M.; Andres, E.

    Drag resistances of newly applied antifouling coatings and welding seams on ship hull surface have been investigated using a pilot-scale rotary setup. Both conventional biocide-based antifouling (AF) coatings and silicone-based fouling release (FR) coatings have been studied and compared in their......Drag resistances of newly applied antifouling coatings and welding seams on ship hull surface have been investigated using a pilot-scale rotary setup. Both conventional biocide-based antifouling (AF) coatings and silicone-based fouling release (FR) coatings have been studied and compared...

  6. Influence of drag force upon the shortest time trajectory of an aircraft

    Directory of Open Access Journals (Sweden)

    Andrei CRAIFALEANU

    2015-06-01

    Full Text Available The shortest time trajectory of an aircraft between two given locations is determined using a simple mathematical model. By taking into account the drag force (viscous friction force with the air, a problem of variational calculus is obtained which consists in determining two functions that minimize a functional, subject to a non-holonomic constraint. The trajectory is determined directly, by numerical integration of Euler equations with multipliers. Three types of drag forces were considered: constant, linear and quadratic. The results are verified through comparison to the values obtained from numerical minimization of the involved functional approximate forms.

  7. ISM-induced erosion and gas-dynamical drag in the Oort Cloud

    International Nuclear Information System (INIS)

    Stern, S.A.

    1990-01-01

    The model presently used to examine the physical interactions between the ISM and the Oort Cloud can account for sputtering, sticking, and grain-impact erosion, as well as gas drag, by envisioning the ISM as a multiphase medium with distinct atomic and molecular cloud-phase regimes and coronal and warm/ambient gas-phase regimes. Erosion, which reduces the effectiveness of the thermal and radiation-damage processes acting on cometary surfaces in the Oort cloud, is found to be the dominant ISM interaction; ISM drag effects were found to efficiently remove submicron particles from the Cloud. 67 refs

  8. ISM-induced erosion and gas-dynamical drag in the Oort Cloud

    Science.gov (United States)

    Stern, S. Alan

    1990-01-01

    The model presently used to examine the physical interactions between the ISM and the Oort Cloud can account for sputtering, sticking, and grain-impact erosion, as well as gas drag, by envisioning the ISM as a multiphase medium with distinct atomic and molecular cloud-phase regimes and coronal and warm/ambient gas-phase regimes. Erosion, which reduces the effectiveness of the thermal and radiation-damage processes acting on cometary surfaces in the Oort cloud, is found to be the dominant ISM interaction; ISM drag effects were found to efficiently remove submicron particles from the Cloud.

  9. On the determination of the neutral drag coefficient in the convective boundary layer

    DEFF Research Database (Denmark)

    Grachev, A.A.; Fairall, C.W.; Larsen, Søren Ejling

    1998-01-01

    Based on the idea that free convection can be considered as a particular case of forced convection, where the gusts driven by the large-scale eddies are scaled with the Deardorff convective velocity scale, a new formulation for the neutral drag coefficient, C-Dn, in the convective boundary layer...... for mean wind speed less than about 2 m s(-1). The new approach also clarifies several contradictory results from earlier works. Some aspects related to an alternate definition of the neutral drag coefficient and the wind speed and the stress averaging procedure are considered....

  10. Microscopic Theory of Magnon-Drag Thermoelectric Transport in Ferromagnetic Metals

    OpenAIRE

    Miura, Daisuke; Sakuma, Akimasa

    2012-01-01

    A theoretical study of the magnon-drag Peltier and Seebeck effects in ferromagnetic metals is presented. A magnon heat current is described perturbatively from the microscopic viewpoint with respect to electron--magnon interactions and the electric field. Then, the magnon-drag Peltier coefficient $\\Pi_\\MAG$ is obtained as the ratio between the magnon heat current and the electric charge current. We show that $\\Pi_\\MAG=C_\\MAG T^{5/2}$ at a low temperature $T$; that the coefficient $C_\\MAG$ is ...

  11. Dusty plasmas in a constant electric field: Role of the electron drag force

    International Nuclear Information System (INIS)

    Khrapak, S.A.; Morfill, G.E.

    2004-01-01

    We investigate the forces experienced by a microparticle immersed in a weakly ionized plasma with constant electric field. These are electric force and the forces associated with the momentum transfer from electrons and ions drifting in the field (electron and ion drag forces). It is shown that the effect of the electron drag, which is often neglected, can be substantial in a certain parameter range. Numerical calculation of the forces for a reasonable set of plasma parameters is performed to illustrate the importance of this effect

  12. FANTOM5 CAGE profiles of human and mouse samples

    NARCIS (Netherlands)

    Noguchi, Shuhei; Arakawa, Takahiro; Fukuda, Shiro; Furuno, Masaaki; Hasegawa, Akira; Hori, Fumi; Ishikawa-Kato, Sachi; Kaida, Kaoru; Kaiho, Ai; Kanamori-Katayama, Mutsumi; Kawashima, Tsugumi; Kojima, Miki; Kubosaki, Atsutaka; Manabe, Ri-ichiroh; Murata, Mitsuyoshi; Nagao-Sato, Sayaka; Nakazato, Kenichi; Ninomiya, Noriko; Nishiyori-Sueki, Hiromi; Noma, Shohei; Saijyo, Eri; Saka, Akiko; Sakai, Mizuho; Simon, Christophe; Suzuki, Naoko; Tagami, Michihira; Watanabe, Shoko; Yoshida, Shigehiro; Arner, Peter; Axton, Richard A.; Babina, Magda; Baillie, J. Kenneth; Barnett, Timothy C.; Beckhouse, Anthony G.; Blumenthal, Antje; Bodega, Beatrice; Bonetti, Alessandro; Briggs, James; Brombacher, Frank; Carlisle, Ailsa J.; Clevers, Hans C.; Davis, Carrie A.; Detmar, Michael; Dohi, Taeko; Edge, Albert S. B.; Edinger, Matthias; Ehrlund, Anna; Ekwall, Karl; Endoh, Mitsuhiro; Enomoto, Hideki; Eslami, Afsaneh; Fagiolini, Michela; Fairbairn, Lynsey; Farach-Carson, Mary C.; Faulkner, Geoffrey J.; Ferrai, Carmelo; Fisher, Malcolm E.; Forrester, Lesley M.; Fujita, Rie; Furusawa, Jun-ichi; Geijtenbeek, Teunis B.; Gingeras, Thomas; Goldowitz, Daniel; Guhl, Sven; Guler, Reto; Gustincich, Stefano; Ha, Thomas J.; Hamaguchi, Masahide; Hara, Mitsuko; Hasegawa, Yuki; Herlyn, Meenhard; Heutink, Peter; Hitchens, Kelly J.; Hume, David A.; Ikawa, Tomokatsu; Ishizu, Yuri; Kai, Chieko; Kawamoto, Hiroshi; Kawamura, Yuki I.; Kempfle, Judith S.; Kenna, Tony J.; Kere, Juha; Khachigian, Levon M.; Kitamura, Toshio; Klein, Sarah; Klinken, S. Peter; Knox, Alan J.; Kojima, Soichi; Koseki, Haruhiko; Koyasu, Shigeo; Lee, Weonju; Lennartsson, Andreas; Mackay-sim, Alan; Mejhert, Niklas; Mizuno, Yosuke; Morikawa, Hiromasa; Morimoto, Mitsuru; Moro, Kazuyo; Morris, Kelly J.; Motohashi, Hozumi; Mummery, Christine L.; Nakachi, Yutaka; Nakahara, Fumio; Nakamura, Toshiyuki; Nakamura, Yukio; Nozaki, Tadasuke; Ogishima, Soichi; Ohkura, Naganari; Ohno, Hiroshi; Ohshima, Mitsuhiro; Okada-Hatakeyama, Mariko; Okazaki, Yasushi; Orlando, Valerio; Ovchinnikov, Dmitry A.; Passier, Robert; Patrikakis, Margaret; Pombo, Ana; Pradhan-Bhatt, Swati; Qin, Xian-Yang; Rehli, Michael; Rizzu, Patrizia; Roy, Sugata; Sajantila, Antti; Sakaguchi, Shimon; Sato, Hiroki; Satoh, Hironori; Savvi, Suzana; Saxena, Alka; Schmidl, Christian; Schneider, Claudio; Schulze-Tanzil, Gundula G.; Schwegmann, Anita; Sheng, Guojun; Shin, Jay W.; Sugiyama, Daisuke; Sugiyama, Takaaki; Summers, Kim M.; Takahashi, Naoko; Takai, Jun; Tanaka, Hiroshi; Tatsukawa, Hideki; Tomoiu, Andru; Toyoda, Hiroo; van de Wetering, Marc; van den Berg, Linda M.; Verardo, Roberto; Vijayan, Dipti; Wells, Christine A.; Winteringham, Louise N.; Wolvetang, Ernst; Yamaguchi, Yoko; Yamamoto, Masayuki; Yanagi-Mizuochi, Chiyo; Yoneda, Misako; Yonekura, Yohei; Zhang, Peter G.; Zucchelli, Silvia; Abugessaisa, Imad; Arner, Erik; Harshbarger, Jayson; Kondo, Atsushi; Lassmann, Timo; Lizio, Marina; Sahin, Serkan; Sengstag, Thierry; Severin, Jessica; Shimoji, Hisashi; Suzuki, Masanori; Suzuki, Harukazu; Kawai, Jun; Kondo, Naoto; Itoh, Masayoshi; Daub, Carsten O.; Kasukawa, Takeya; Kawaji, Hideya; Carninci, Piero; Forrest, Alistair R. R.; Hayashizaki, Yoshihide

    2017-01-01

    In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples,

  13. STS-49 Landing at Edwards with First Drag Chute Landing

    Science.gov (United States)

    1992-01-01

    The Space Shuttle Endeavour concludes mission STS-49 at NASA's Ames-Dryden Flight Research Facility (later redesignated Dryden Flight Research Center), Edwards, California, with a 1:57 p.m. (PDT) landing 16 May on Edward's concrete runway 22. The planned 7-day mission, which began with a launch from Kennedy Space Center, Florida, at 4:41 p.m. (PFT), 7 May, was extended two days to allow extra time to rescue the Intelsat VI satellite and complete Space Station assembly techniques originally planned. After a perfect rendezvous in orbit and numerous attempts to grab the satellite, space walking astronauts Pierre Thuot, Rick Hieb and Tom Akers successfully rescued it by hand on the third space walk with the support of mission specialists Kathy Thornton and Bruce Melnick. The three astronauts, on a record space walk, took hold of the satellite and directed it to the shuttle where a booster motor was attached to launch it to its proper orbit. Commander Dan Brandenstein and Pilot Kevin Chilton brought Endeavours's record setting maiden voyage to a perfect landing at Edwards AFB with the first deployment of a drag chute on a shuttle mission. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their

  14. STS-58 Landing at Edwards with Drag Chute

    Science.gov (United States)

    1993-01-01

    A drag chute slows the space shuttle Columbia as it rolls to a perfect landing concluding NASA's longest mission at that time, STS-58, at the Ames-Dryden Flight Research Facility (later redesignated the Dryden Flight Research Center), Edwards, California, with a 8:06 a.m. (PST) touchdown 1 November 1993 on Edward's concrete runway 22. The planned 14 day mission, which began with a launch from Kennedy Space Center, Florida, at 7:53 a.m. (PDT), October 18, was the second spacelab flight dedicated to life sciences research. Seven Columbia crewmembers performed a series of experiments to gain more knowledge on how the human body adapts to the weightless environment of space. Crewmembers on this flight included: John Blaha, commander; Rick Searfoss, pilot; payload commander Rhea Seddon; mission specialists Bill MacArthur, David Wolf, and Shannon Lucid; and payload specialist Martin Fettman. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space

  15. A biomechanical comparison in the lower limb and lumbar spine between a hit and drag flick in field hockey.

    Science.gov (United States)

    Ng, Leo; Rosalie, Simon M; Sherry, Dorianne; Loh, Wei Bing; Sjurseth, Andreas M; Iyengar, Shrikant; Wild, Catherine Y

    2018-03-01

    Research has revealed that field hockey drag flickers have greater odds of hip and lumbar injuries compared to non-drag flickers (DF). This study aimed to compare the biomechanics of a field hockey hit and a specialised field hockey drag flick. Eighteen male and seven female specialised hockey DF performed a hit and a drag flick in a motion analysis laboratory with an 18-camera three-dimensional motion analysis system and a calibrated multichannel force platform to examine differences in lower limb and lumbar kinematics and kinetics. Results revealed that drag flicks were performed with more of a forward lunge on the left lower limb resulting in significantly greater left ankle dorsiflexion, knee, hip and lumbar flexion (Pshit. Drag flicks were also performed with significantly greater lateral flexion (P hit. Differences in kinematics lead to greater shear, compression and tensile forces in multiple left lower limb and lumbar joints in the drag flick compared to the hit (P hit may have ramifications with respect to injury in field hockey drag flickers.

  16. Direct numerical simulations of drag reduction in turbulent channel flow over bio-inspired herringbone riblet-texture

    NARCIS (Netherlands)

    Benschop, H.O.G.; Westerweel, J.; Breugem, W.P.

    2015-01-01

    The use of drag reducing surface textures is a promising passive method to reduce fuel consumption. Probably most wellknown is the utilisation of shark-skin inspired ridges or riblets parallel to the mean flow. They can reduce drag up to 10%. Recently another bio-inspired texture based on bird

  17. Effect of local energy supply to a hypersonic flow on the drag of bodies with different nose bluntness

    International Nuclear Information System (INIS)

    Borzov, V.Yu.; Rybka, I.V.; Yur'ev, A.S.

    1995-01-01

    Parameters of the axisymmetric flow around bodies with different bluntness are compared in the case of constant energy supply to the main hypersonic flow. Flow structures, drag coefficients, and expenditure of energy on overcoming drag are analyzed with the effect of thermal energy on the flow taken into account for different bodies with equal volume

  18. High Speed Civil Transport (HSCT) Isolated Nacelle Transonic Boattail Drag Study and Results Using Computational Fluid Dynamics (CFD)

    Science.gov (United States)

    Midea, Anthony C.; Austin, Thomas; Pao, S. Paul; DeBonis, James R.; Mani, Mori

    2005-01-01

    Nozzle boattail drag is significant for the High Speed Civil Transport (HSCT) and can be as high as 25 percent of the overall propulsion system thrust at transonic conditions. Thus, nozzle boattail drag has the potential to create a thrust drag pinch and can reduce HSCT aircraft aerodynamic efficiencies at transonic operating conditions. In order to accurately predict HSCT performance, it is imperative that nozzle boattail drag be accurately predicted. Previous methods to predict HSCT nozzle boattail drag were suspect in the transonic regime. In addition, previous prediction methods were unable to account for complex nozzle geometry and were not flexible enough for engine cycle trade studies. A computational fluid dynamics (CFD) effort was conducted by NASA and McDonnell Douglas to evaluate the magnitude and characteristics of HSCT nozzle boattail drag at transonic conditions. A team of engineers used various CFD codes and provided consistent, accurate boattail drag coefficient predictions for a family of HSCT nozzle configurations. The CFD results were incorporated into a nozzle drag database that encompassed the entire HSCT flight regime and provided the basis for an accurate and flexible prediction methodology.

  19. Improved theoretical approximation for the ion drag force in collisionless plasma with strong ion-grain coupling

    International Nuclear Information System (INIS)

    Khrapak, S. A.; Nosenko, V.; Morfill, G. E.; Merlino, R.

    2009-01-01

    We point out a deficiency in our previous analytic calculation of the ion drag force for conditions of the experiment by Nosenko et al. [Phys. Plasmas 14, 103702 (2007)]. An inaccurate approximation is corrected and the ion drag force is recalculated. The improved model yields better overall agreement with the experimental results as compared to the original calculation.

  20. Trade-off between drag reduction and light interception of macrophytes: comparing five aquatic plants with contrasting morphology

    NARCIS (Netherlands)

    Bal, K.D.; Bouma, T.J.; Buis, K.; Struyf, E.; Jonas, S.; Backx, H.; Meire, P.

    2011-01-01

    1. Macrophytes in running waters experience an often dynamic and harsh environment. To avoid breakage, plants have to reduce the experienced drag force. However, by reducing leaf area, photosynthetic production is less. Aquatic plants therefore have to find a balance between reducing drag and

  1. Electric Motorboat Drag Racing: A Hands-On Physics Project that Motivates Students from Start to Finish

    Science.gov (United States)

    Barry, Reno

    2008-01-01

    Electric Motorboat Drag Racing is a culminating high school physics project designed to apply and bring to life many content standards for physics. Students need to be given several weeks at home to design and build their model-sized electric motorboats for the 5-meter drag racing competition down rain gutters. In the process, they are discussing…

  2. Burn mouse models

    DEFF Research Database (Denmark)

    Calum, Henrik; Høiby, Niels; Moser, Claus

    2014-01-01

    Severe thermal injury induces immunosuppression, involving all parts of the immune system, especially when large fractions of the total body surface area are affected. An animal model was established to characterize the burn-induced immunosuppression. In our novel mouse model a 6 % third-degree b......Severe thermal injury induces immunosuppression, involving all parts of the immune system, especially when large fractions of the total body surface area are affected. An animal model was established to characterize the burn-induced immunosuppression. In our novel mouse model a 6 % third...... with infected burn wound compared with the burn wound only group. The burn mouse model resembles the clinical situation and provides an opportunity to examine or develop new strategies like new antibiotics and immune therapy, in handling burn wound victims much....

  3. Leidenfrost vapour layer moderation of the drag crisis and trajectories of superhydrophobic and hydrophilic spheres falling in water

    KAUST Repository

    Vakarelski, Ivan Uriev; Chan, Derek Y C; Thoroddsen, Sigurdur T

    2014-01-01

    We investigate the dynamic effects of a Leidenfrost vapour layer sustained on the surface of heated steel spheres during free fall in water. We find that a stable vapour layer sustained on the textured superhydrophobic surface of spheres falling through 95 °C water can reduce the hydrodynamic drag by up to 75% and stabilize the sphere trajectory for the Reynolds number between 104 and 106, spanning the drag crisis in the absence of the vapour layer. For hydrophilic spheres under the same conditions, the transition to drag reduction and trajectory stability occurs abruptly at a temperature different from the static Leidenfrost point. The observed drag reduction effects are attributed to the disruption of the viscous boundary layer by the vapour layer whose thickness depends on the water temperature. Both the drag reduction and the trajectory stabilization effects are expected to have significant implications for development of sustainable vapour layer based technologies. © the Partner Organisations 2014.

  4. On the development of lift and drag in a rotating and translating cylinder

    Science.gov (United States)

    Martin-Alcantara, Antonio; Sanmiguel-Rojas, Enrique; Fernandez-Feria, Ramon

    2014-11-01

    The two-dimensional flow around a rotating cylinder is investigated numerically using a vorticity forces formulation with the aim of analyzing the flow structures, and their evolutions, that contribute to the lift and drag forces on the cylinder. The Reynolds number, based on the cylinder diameter and steady free-stream speed, considered is Re = 200 , while the non-dimensional rotation rate (ratio of the surface speed and free-stream speed) selected were α = 1 and 3. For α = 1 the wake behind the cylinder for the fully developed flow is oscillatory due to vortex shedding, and so are the lift and drag forces. For α = 3 the fully developed flow is steady with constant (high) lift and (low) drag. Each of these cases is considered in two different transient problems, one with angular acceleration of the cylinder and constant speed, and the other one with translating acceleration of the cylinder and constant rotation. Special attention is paid to explaining the mechanisms of vortex shedding suppression for high rotation (when α = 3) and its relation to the mechanisms by which the lift is enhanced and the drag is almost suppressed when the fully developed flow is reached. Supported by the Ministerio de Economia y Competitividad of Spain Grant No. DPI2013-40479-P.

  5. Optimizing Internal Wave Drag in a Forward Barotropic Model with Semidiurnal Tides

    Science.gov (United States)

    2015-01-23

    rates and patterns after tuning. This suggests that the directionality of the tensor scheme may not provide substantial additional benefit compared to...wave drag scheme Model (layers) Res [] Observations RMSE >1 km [cm] RMSE all depths [cm] Jayne and St. Laurent (2001) JSL JSL(1) 1=2 UT- CSR 6:7$ Egbert

  6. Atmospheric Drag, Occultation ‘N’ Ionospheric Scintillation (ADONIS) mission proposal

    Czech Academy of Sciences Publication Activity Database

    Hettrich, S.; Kempf, Y.; Perakis, N.; Górski, J.; Edl, M.; Urbář, Jaroslav; Dósa, M.; Gini, F.; Roberts, O. W.; Schindler, S.; Schemmer, M.; Steenari, D.; Joldžić, N.; Ødegaard, L.-K. G.; Sarria, D.; Volwerk, M.; Praks, J.

    2015-01-01

    Roč. 5, Article Number: A2 (2015), s. 1-14 ISSN 2115-7251 Institutional support: RVO:68378289 Keywords : ionosphere (general) * thermosphere * space weather * drag * missions Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.846, year: 2015 http://www.swsc-journal.org/articles/swsc/abs/2015/01/swsc140006/swsc140006.html

  7. The influence of longitudinal micro grooves on hydrodynamic friction drag of a plate

    Directory of Open Access Journals (Sweden)

    В.І. Коробов

    2005-01-01

    Full Text Available  Weight measurements in a water tunnel have shown that there exist a range of parameters of longitudinally fine-ribbed surface such that turbulent friction in flow over the surface is less than that over a smooth flat plane of the same projected area. Maximum drag reduction due to ribbing is up to 16%.

  8. Self-determined shapes and velocities of giant near-zero drag gas cavities

    KAUST Repository

    Vakarelski, Ivan Uriev

    2017-09-09

    Minimizing the retarding force on a solid moving in liquid is the canonical problem in the quest for energy saving by friction and drag reduction. For an ideal object that cannot sustain any shear stress on its surface, theory predicts that drag force will fall to zero as its speed becomes large. However, experimental verification of this prediction has been challenging. We report the construction of a class of self-determined streamlined structures with this free-slip surface, made up of a teardrop-shaped giant gas cavity that completely encloses a metal sphere. This stable gas cavity is formed around the sphere as it plunges at a sufficiently high speed into the liquid in a deep tank, provided that the sphere is either heated initially to above the Leidenfrost temperature of the liquid or rendered superhydrophobic in water at room temperature. These sphere-in-cavity structures have residual drag coefficients that are typically less than Embedded Image those of solid objects of the same dimensions, which indicates that they experienced very small drag forces. The self-determined shapes of the gas cavities are shown to be consistent with the Bernoulli equation of potential flow applied on the cavity surface. The cavity fall velocity is not arbitrary but is uniquely predicted by the sphere density and cavity volume, so larger cavities have higher characteristic velocities.

  9. 76 FR 52263 - Special Local Regulation for Marine Events; Mattaponi Madness Drag Boat Race, Mattaponi River...

    Science.gov (United States)

    2011-08-22

    ... hour, make special local regulations necessary. However, the Coast Guard will provide advance... dangers posed by drag boat racing, operating in speeds excess of 150 miles per hour, make special local... side activities in the event area. The category of water activities includes but is not limited to sail...

  10. The strong thermoelectric effect in nanocarbon generated by the ballistic phonon drag of electrons

    International Nuclear Information System (INIS)

    Eidelman, E D; Vul', A Ya

    2007-01-01

    The thermoelectric power and thermoelectric figure of merit for carbon nanostructure consisting of graphite-like (sp 2 ) and diamond-like (sp 3 ) regions have been investigated. The probability of electron collisions with quasi-ballistic phonons in sp 2 regions has been analysed for the first time. We have shown that the probability is not small. We have analysed the influence of various factors on the process of the electron-ballistic phonon drag (the phonon drag effect). The thermoelectric power and thermoelectric figure of merit under conditions of ballistic transport were found to be substantially higher than those in the cases of drag by thermalized phonons and of electron diffusion. The thermoelectric figure of merit (ZT) in the case of a ballistic phonon contribution to the phonon drag of electrons should be 50 times that for chaotic phonons and 500 times that in the case of the diffusion process. In that case ZT should be a record (ZT≥2-3)

  11. Development of a New Drag Coefficient Model for Oil and Gas ...

    African Journals Online (AJOL)

    Development of a New Drag Coefficient Model for Oil and Gas Multiphase Fluid Systems. ... a helpful Frequently Asked Questions about PDFs. Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

  12. Plasmon enhancement of Coulomb drag in double-quantum-well systems

    DEFF Research Database (Denmark)

    Flensberg, Karsten; Hu, Ben Yu-Kuang

    1995-01-01

    We derive an expression for the drag rate (i.e., interlayer momentum transfer rate) for carriers in two coupled two-dimensional gases to lowest nonvanishing order in the screened interlayer electron-electron interaction, valid for arbitrary intralayer scattering mechanisms, using the Boltzmann tr...

  13. Experimental Studies on the Physics and Technology of Polymer Drag-Reduction

    National Research Council Canada - National Science Library

    Hanratty, Thomas

    2004-01-01

    .... Companion studies were carried out in the polymer laboratory of Anthony J. McHugh so that the performance of drag-reducing polymer solutions can be related to their rheological and rheo-optical properties in simple non-turbulent flows...

  14. An Examination of Drag Reduction Mechanisms in Marine Animals, with Potential Applications to Uninhabited Aerial Vehicles

    Science.gov (United States)

    Musick, John A.; Patterson, Mark R.; Dowd, Wesley W.

    2002-01-01

    Previous engineering research and development has documented the plausibility of applying biomimetic approaches to aerospace engineering. Past cooperation between the Virginia Institute of Marine Science (VIMS) and NASA focused on the drag reduction qualities of the microscale dermal denticles of shark skin. This technology has subsequently been applied to submarines and aircraft. The present study aims to identify and document the three-dimensional geometry of additional macroscale morphologies that potentially confer drag reducing hydrodynamic qualities upon marine animals and which could be applied to enhance the range and endurance of Uninhabited Aerial Vehicles (UAVs). Such morphologies have evolved over eons to maximize organismal energetic efficiency by reducing the energetic input required to maintain cruising speeds in the viscous marine environment. These drag reduction qualities are manifested in several groups of active marine animals commonly encountered by ongoing VIMS research programs: namely sharks, bony fishes such as tunas, and sea turtles. Through spatial data acquired by molding and digital imagery analysis of marine specimens provided by VIMS, NASA aims to construct scale models of these features and to test these potential drag reduction morphologies for application to aircraft design. This report addresses the efforts of VIMS and NASA personnel on this project between January and November 2001.

  15. Experimental Studies on the Physics and Technology of Polymer Drag-Reduction

    National Research Council Canada - National Science Library

    Hanratty, Thomas

    2004-01-01

    .... Rheo-optical studies in a Couette device showed that effective polymer solutions develop turbidity over a range of shear rates characteristic of those used in the flow loop. This study shows that the drag reduction can be enhanced by using mixing and delivery procedures which enhance the formation aggregates.

  16. Magnetoquantum oscillations of the phonon-drag thermoelectric power in heterojunctions

    International Nuclear Information System (INIS)

    Lyo, S.K.

    1989-01-01

    A theory is presented for the low-temperature phonon-drag thermopower S xx in a semiconductor heterojunction in a strong magnetic field. Gigantic quantum oscillations (much larger than electron-diffusion contributions) are obtained. The temperature and field dependences of S xx agree well with recent data. Localized states yield flat valleys for the |S xx | minima in agreement with the data

  17. Ocean's response to Hurricane Frances and its implications for drag coefficient parameterization at high wind speeds

    KAUST Repository

    Zedler, S. E.

    2009-04-25

    The drag coefficient parameterization of wind stress is investigated for tropical storm conditions using model sensitivity studies. The Massachusetts Institute of Technology (MIT) Ocean General Circulation Model was run in a regional setting with realistic stratification and forcing fields representing Hurricane Frances, which in early September 2004 passed east of the Caribbean Leeward Island chain. The model was forced with a NOAA-HWIND wind speed product after converting it to wind stress using four different drag coefficient parameterizations. Respective model results were tested against in situ measurements of temperature profiles and velocity, available from an array of 22 surface drifters and 12 subsurface floats. Changing the drag coefficient parameterization from one that saturated at a value of 2.3 × 10 -3 to a constant drag coefficient of 1.2 × 10-3 reduced the standard deviation difference between the simulated minus the measured sea surface temperature change from 0.8°C to 0.3°C. Additionally, the standard deviation in the difference between simulated minus measured high pass filtered 15-m current speed reduced from 15 cm/s to 5 cm/s. The maximum difference in sea surface temperature response when two different turbulent mixing parameterizations were implemented was 0.3°C, i.e., only 11% of the maximum change of sea surface temperature caused by the storm. Copyright 2009 by the American Geophysical Union.

  18. Drag force of intermediate Reynolds number flow past mono- and bidisperse arrays of spheres

    NARCIS (Netherlands)

    Beetstra, R.; van der Hoef, Martin Anton; Kuipers, J.A.M.

    2007-01-01

    Extensive lattice-Boltzmann simulations were performed to obtain the drag force for random arrays of monodisperse and bidisperse spheres. For the monodisperse systems, 35 different combinations of the Reynolds number Re (up to Re = 1,000) and packing fraction were studied, whereas for the bidisperse

  19. Drag force of intermediate Reynolds number flow past mono- and bidisperse arrays of spheres

    NARCIS (Netherlands)

    Beetstra, R.; Hoef, van der M.A.; Kuipers, J.A.M.

    2007-01-01

    Extensive lattice-Boltzmann simulations were performed to obtain the drag force for random arrays of monodisperse and bidisperse spheres. For the monodisperse systems, 35 different combinations of the Reynolds number Re (up to Re = 1,000) and packing fraction ¿ were studied, whereas for the

  20. Experimental Evaluation of the Drag Coefficient of Water Rockets by a Simple Free-Fall Test

    Science.gov (United States)

    Barrio-Perotti, R.; Blanco-Marigorta, E. Arguelles-Diaz, K.; Fernandez-Oro, J.

    2009-01-01

    The flight trajectory of a water rocket can be reasonably calculated if the magnitude of the drag coefficient is known. The experimental determination of this coefficient with enough precision is usually quite difficult, but in this paper we propose a simple free-fall experiment for undergraduate students to reasonably estimate the drag…

  1. Comparison of gimbal approaches to decrease drag force and radar cross sectional area in missile application

    Science.gov (United States)

    Sakarya, Doǧan Uǧur

    2017-05-01

    Drag force effect is an important aspect of range performance in missile applications especially for long flight time. However, old fashioned gimbal approaches force to increase missile diameter. This increase has negative aspect of rising in both drag force and radar cross sectional area. A new gimbal approach was proposed recently. It uses a beam steering optical arrangement. Therefore, it needs less volume envelope for same field of regard and same optomechanical assembly than the old fashioned gimbal approaches. In addition to longer range performance achieved with same fuel in the new gimbal approach, this method provides smaller cross sectional area which can be more invisible in enemies' radar. In this paper, the two gimbal approaches - the old fashioned one and the new one- are compared in order to decrease drag force and radar cross sectional area in missile application. In this study; missile parameters are assumed to generate gimbal and optical design parameters. Optical design is performed according to these missile criteria. Two gimbal configurations are designed with respect to modeled missile parameters. Also analyzes are performed to show decreased drag force and radar cross sectional area in the new approach for comparison.

  2. Design of a High Viscosity Couette Flow Facility for Patterned Surface Drag Measurements

    Science.gov (United States)

    Johnson, Tyler; Lang, Amy

    2009-11-01

    Direct drag measurements can be difficult to obtain with low viscosity fluids such as air or water. In this facility, mineral oil is used as the working fluid to increase the shear stress across the surface of experimental models. A mounted conveyor creates a flow within a plexiglass tank. The experimental model of a flat or patterned surface is suspended above a moving belt. Within the gap between the model and moving belt a Couette flow with a linear velocity profile is created. PIV measurements are used to determine the exact velocities and the Reynolds numbers for each experiment. The model is suspended by bars that connect to the pillow block housing of each bearing. Drag is measured by a force gauge connected to linear roller bearings that slide along steel rods. The patterned surfaces, initially consisting of 2-D cavities, are embedded in a plexiglass plate so as to keep the total surface area constant for each experiment. First, the drag across a flat plate is measured and compared to theoretical values for laminar Couette flow. The drag for patterned surfaces is then measured and compared to a flat plate.

  3. Drag Measurements over Embedded Cavities in a Low Reynolds Number Couette Flow

    Science.gov (United States)

    Gilmer, Caleb; Lang, Amy; Jones, Robert

    2010-11-01

    Recent research has revealed that thin-walled, embedded cavities in low Reynolds number flow have the potential to reduce the net viscous drag force acting on the surface. This reduction is due to the formation of embedded vortices allowing the outer flow to pass over the surface via a roller bearing effect. It is also hypothesized that the scales found on butterfly wings may act in a similar manner to cause a net increase in flying efficiency. In this experimental study, rectangular embedded cavities were designed as a means of successfully reducing the net drag across surfaces in a low Reynolds number flow. A Couette flow was generated via a rotating conveyor belt immersed in a tank of high viscosity mineral oil above which the plates with embedded cavities were placed. Drag induced on the plate models was measured using a force gauge and compared directly to measurements acquired over a flat plate. Various cavity aspect ratios and gap heights were tested in order to determine the conditions under which the greatest drag reductions occurred.

  4. A following car influences cyclist drag: CFD simulations and wind tunnel measurements

    NARCIS (Netherlands)

    Blocken, B.J.E.; Toparlar, Y.

    2015-01-01

    It is well-known in elite cycling that a cyclist riding behind a car experiences a substantial reduction in aerodynamic resistance or drag. However, the upstream effect by a following car on the cyclist in front of it is not well-known and has, to the best of our knowledge, not yet been reported in

  5. Phonon Drag in Thin Films, Cases of Bi2Te3 and ZnTe

    Science.gov (United States)

    Chi, Hang; Uher, Ctirad

    2014-03-01

    At low temperatures, in (semi-)conductors subjected to a thermal gradient, charge carriers (electrons and holes) are swept (dragged) by out-of-equilibrium phonons due to strong electron-phonon interaction, giving rise to a large contribution to the Seebeck coefficient called the phonon-drag effect. Such phenomenon was surprisingly observed in our recent transport study of highly mismatched alloys as potential thermoelectric materials: a significant phonon-drag thermopower reaching 1.5-2.5 mV/K was recorded for the first time in nitrogen-doped ZnTe epitaxial layers on GaAs (100). In thin films of Bi2Te3, we demonstrate a spectacular influence of substrate phonons on charge carriers. We show that one can control and tune the position and magnitude of the phonon-drag peak over a wide range of temperatures by depositing thin films on substrates with vastly different Debye temperatures. Our experiments also provide a way to study the nature of the phonon spectrum in thin films, which is rarely probed but clearly important for a complete understanding of thin film properties and the interplay of the substrate and films. This work is supported by the Center for Solar and Thermal Energy Conversion, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award Number DE-SC0000957.

  6. Self-similar drag reduction in plug-flow of suspensions of macroscopic fibers

    NARCIS (Netherlands)

    Gillissen, J.J.J.; Hoving, J.P.

    2012-01-01

    Pipe flow experiments show that turbulent drag reduction in plug-flow of concentrated suspensions of macroscopic fibers is a self-similar function of the wall shear stress over the fiber network yield stress. We model the experimental observations, by assuming a central fiber network plug, whose

  7. Wigs, laughter, and subversion: Charles Busch and strategies of drag performance.

    Science.gov (United States)

    Niles, Richard

    2004-01-01

    This paper examines the strategies of drag performer/ playwright Charles Busch. His performance aesthetic is explored and shown to be subversive even though its initial impulse is to entertain. Basing my arguments on the work of Judith Butler, Elin Diamond, and others, I argue that drag queens like Busch can not only entertain but also make audiences question and criticize through drag's power to create a Brechtian alienation effect and historicize the subject. After showing how he can be viewed as a drag queen, I give a brief biography and discuss such contested terms as "camp" and "gay sensibility." I then focus on Busch's staged reading of Ibsen's Hedda Gahler andA Doll's House, both done in one afternoon at Theatre for The New City (6 May 2000). By examining the performance of Busch and his fellow actors, I demonstrate how a contemporary relevancy is achieved by having the roles played by a female impersonator whose acting choices are filtered through a gay sensibility. The ongoing dialectic between spectator and performer creates a historicized moment in performance that underscores the gender dynamics in unexpected and stimulating ways.

  8. Hydrodynamic Drag Force Measurement Of A Functionalized Surface Exhibiting Superhydrophobic Properties

    Science.gov (United States)

    2016-12-01

    hydrodynamic skin friction is greatly reduced and the water is said to slip over the air layer [12]. A number of direct numerical simulations ( DNS ) [13...practical means of reducing drag. It is therefore important to investigate materials where in the passive state exhibit the desired qualities of

  9. External drag body as flow meter according to the principle of Karman's vortex path

    International Nuclear Information System (INIS)

    Heinze, K.; Lipowski, K.

    1977-01-01

    A simple external drag body is described which can easily be manufactured and by which measuring signals can be obtained having got amplitudes which lie considerably above the disturbances. At the same time a damping effect as large as possible is exerted on turbulent flows. (RW) [de

  10. Development of a New Drag Coefficient Model for Oil and Gas ...

    African Journals Online (AJOL)

    Development of a New Drag Coefficient Model for Oil and Gas Multiphase Fluid Systems. ... PROMOTING ACCESS TO AFRICAN RESEARCH ... suspensions of solid particles are frequently encountered in many industrial processes including oil & gas production. ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  11. Effects of cusped field thruster on the performance of drag-free control system

    Science.gov (United States)

    Cui, K.; Liu, H.; Jiang, W. J.; Sun, Q. Q.; Hu, P.; Yu, D. R.

    2018-03-01

    With increased measurement tasks of space science, more requirements for the spacecraft environment have been put forward. Those tasks (e.g. the measurement of Earth's steady state gravity field anomalies) lead to the desire for developing drag-free control. Higher requirements for the thruster performance are made due to the demand for the drag-free control system and real-time compensation for non-conservative forces. Those requirements for the propulsion system include wide continuous throttling ability, high resolution, rapid response, low noise and so on. As a promising candidate, the cusped field thruster has features such as the high working stability, the low erosion rate, a long lifetime and the simple structure, so that it is chosen as the thruster to be discussed in this paper. Firstly, the performance of a new cusped field thruster is tested and analyzed. Then a drag-free control scheme based on the cusped field thruster is designed to evaluate the performance of this thruster. Subsequently, the effects of the thrust resolution, transient response time and thrust uncertainty on the controller are calculated respectively. Finally, the performance of closed-loop system is analyzed, and the simulation results verify the feasibility of applying cusped field thruster to drag-free flight in the space science measurement tasks.

  12. Gain-assisted superluminal propagation and rotary drag of photon and surface plasmon polaritons

    Science.gov (United States)

    Khan, Naveed; Amin Bacha, Bakht; Iqbal, Azmat; Ur Rahman, Amin; Afaq, A.

    2017-07-01

    Superluminal propagation of light is a well-established phenomenon and has motivated immense research interest that has led to state-of-the-art knowledge and potential applications in the emerging technology of quantum optics and photonics. This study presents a theoretical analysis of the gain-assisted superluminal light propagation in a four-level N -type atomic system by exploiting the scheme of electromagnetically induced gain and superluminal propagation of surface plasmon polaritons (SPPs) along the gain-assisted atomic-metal interface simultaneously. In addition, a theoretical demonstration is presented on the comparison between Fresnel's rotary photon drag and SPP drag in view of light polarization state rotation by rotating the coherent atomic medium and the atomic-metal interface, respectively. Analogous to photon drag in the superluminal anomalous dispersion region where light polarization rotation occurs opposite the rotation of the gain-assisted atomic medium, the rotation of the atomic-metal interface also rotates the polarization state of SPPs opposite the rotation of the interface. This further confirms the superluminal nature of SPPs propagating along the interface with negative group velocity. Rabi frequencies of the control and pump fields considerably modify both photon and SPP drag coefficients. Metal conductivity also controls SPP propagation.

  13. Measurements of long-range enhanced collisional velocity drag through plasma wave damping

    Science.gov (United States)

    Affolter, M.; Anderegg, F.; Dubin, D. H. E.; Driscoll, C. F.

    2018-05-01

    We present damping measurements of axial plasma waves in magnetized, multispecies ion plasmas. At high temperatures T ≳ 10-2 eV, collisionless Landau damping dominates, whereas, at lower temperatures T ≲ 10-2 eV, the damping arises from interspecies collisional drag, which is dependent on the plasma composition and scales roughly as T-3 /2 . This drag damping is proportional to the rate of parallel collisional slowing, and is found to exceed classical predictions of collisional drag damping by as much as an order of magnitude, but agrees with a new collision theory that includes long-range collisions. Centrifugal mass separation and collisional locking of the species occur at ultra-low temperatures T ≲ 10-3 eV, which reduce the drag damping from the T-3 /2 collisional scaling. These mechanisms are investigated by measuring the damping of higher frequency axial modes, and by measuring the damping in plasmas with a non-equilibrium species profile.

  14. The Effects of Propulsive Jetting on Drag of a Streamlined body

    Science.gov (United States)

    Krieg, Michael; Mohseni, Kamran

    2017-11-01

    Recently an abundance of bioinspired underwater vehicles have emerged to leverage eons of evolution. Our group has developed a propulsion technique inspired by jellyfish and squid. Propulsive jets are generated by ingesting and expelling water from a flexible internal cavity. We have demonstrated thruster capabilities for maneuvering on AUV platforms, where the internal thruster geometry minimized forward drag; however, such a setup cannot characterize propulsive efficiency. Therefore, we created a new streamlined vehicle platform that produces unsteady jets for forward propulsion rather than maneuvering. The streamlined jetting body is placed in a water tunnel and held stationary while jetting frequency and background flow velocity are varied. For each frequency/velocity pair the flow field is measured around the surface and in the wake using PIV. Using the zero jetting frequency as a baseline for each background velocity, the passive body drag is related to the velocity distribution. For cases with active jetting the drag and jetting forces are estimated from the velocity field and compared to the passive case. For this streamlined body, the entrainment of surrounding flow into the propulsive jet can reduce drag forces in addition to the momentum transfer of the jet itself. Office of Naval Research.

  15. A wind loading correlation for an isolated square heliostat, part 1: lift and drag forces

    CSIR Research Space (South Africa)

    Roos, TH

    2012-05-01

    Full Text Available dataset to high accuracy. Correlations for the lift and drag forces are presented. A companion paper presents correlations for the side forces and correlations for moments about the three principal axes, and discusses the behavior of the correlations....

  16. Coulomb drag in anisotropic systems: a theoretical study on a double-layer phosphorene

    NARCIS (Netherlands)

    Saberi-Pouya, S.; Vazifehshenas, T.; Farmanbar Gelepordsari, M.; Salavati-Fard, T.

    2016-01-01

    We theoretically study the Coulomb drag resistivity in a double-layer electron system with highly anisotropic parabolic band structure using Boltzmann transport theory. As an example, we consider a double-layer phosphorene on which we apply our formalism. This approach, in principle, can be tuned

  17. Application and numerical simulation research on biomimetic drag-reducing technology for gas pipelining

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Deyuan; Luo Yuehao; Chen Huawei [Beihang Univ., Beijing (China). School of Mechanical Engineering and Automation

    2011-06-15

    For the purpose of increasing the transmission capacity of gas pipelines, the internal coating technology has been vastly put into application, and a remarkable benefit has been achieved so far. However, with the reduction of wall roughness, the small convex parts are all completely submerged in the viscous sublayer, the gas pipeline becomes a 'hydraulic smooth pipe', even by smoothing the coating surface further, it is difficult to reduce wall friction. Therefore, in order to increase the transportation capacity on the basis of internal coating, the new methods and technologies should be researched and investigated, and perhaps, the biomimetic drag-reducing technology is a good approach. In this paper, according to the planning parameters of the second pipeline of the West-to-East gas transmission project, the best drag reducing effect grooves are calculated and designed, and based on the characteristics and properties of internal coating (AW-01 epoxy resin), the Pre-Cured Micro- Rolling Technology (PCMRT) is discussed and presented, the rolling equipment is also designed and analyzed, the rolling process can be easily added on the available production line. Aiming at the field operating parameters of the gas pipeline in China, and the drag-reducing effect of the grooved surface is analyzed and discussed comprehensively. In addition, the economic benefit of adopting the biomimetic drag reduction technology is investigated. (orig.)

  18. Drag coefficient accuracy improvement by means of particle image velocimetry for a transonic NACA0012 airfoil

    International Nuclear Information System (INIS)

    Ragni, D; Van Oudheusden, B W; Scarano, F

    2011-01-01

    A method to improve the reliability of the drag coefficient computation by means of particle image velocimetry measurements is made using experimental data acquired on a NACA0012 airfoil tested in the transonic regime, using the combination of a variable pulse separation with a new high-order Poisson spectral pressure reconstruction algorithm. (technical design note)

  19. Electron and phonon drag in thermoelectric transport through coherent molecular conductors

    DEFF Research Database (Denmark)

    Lü, Jing-Tao; Wang, Jian-Sheng; Hedegård, Per

    2016-01-01

    We study thermoelectric transport through a coherent molecular conductor connected to two electron and two phonon baths using the nonequilibrium Green's function method. We focus on the mutual drag between electron and phonon transport as a result of ‘momentum’ transfer, which happens only when...

  20. Sunspots and the physics of magnetic flux tubes. II. Aerodynamic drag

    International Nuclear Information System (INIS)

    Parker, E.N.

    1979-01-01

    The aerodynamic drag on a slender flux tube stretched vertically across a convective cell may push the flux tube into the updrafts or into the downdrafts, depending on the density stratification of the convecting fluid and the asymmetry of the fluid motions. The drag is approximately proportional to the local kinetic energy density, so the density stratification weights the drag in favor of the upper layers where the density is low, tending to push the vertical tube into the downdrafts. If, however, the horizontal motions in the convective cell are concentrated toward the bottom of the cell, they may dominate over the upper layers, pushing the tube into the updrafts. In the simple, idealized circumstance of a vertical tube extending across a fluid of uniform density in a convective cell that is symmetric about its midplane, the net aerodynamic drag vanishes in lowest order. The higher order contributions, including the deflection of the tube, then provide a nonvanishing force pushing the tube into a stable equilibrium midway between the updraft and the downdraft.It is pointed out that in the strongly stratified convective zone of the Sun, a downdraft herds flux tubes together into a cluster, while an updraft disperses them. To account for the observed strong cohesion of the cluster of flux tubes that make up a sunspot, we propose a downdraft of the order 2 km s - 1 through the cluster of seprate tubes beneath the sunspot

  1. Numerical Characterisation of Active Drag and Lift Control for a Circular Cylinder in Cross-Flow

    Directory of Open Access Journals (Sweden)

    Philip McDonald

    2017-11-01

    Full Text Available Synthetic jet actuators have shown promise to control drag and lift for a bluff body in cross-flow. Using unsteady RANS CFD modelling, a significant modification of the drag coefficient for a circular cylinder in cross-flow at R e = 3900 is achieved by varying the actuation frequency. The variation in actuation frequency corresponds to a range in Stokes number of 2.4 < S t o < 6.4. The trends in drag coefficient modification largely agree with the findings of past publications, achieving a maximum drag reduction at S t o = 4.9 for a fixed jet Reynolds number of the synthetic jet of R e U ¯ o = 12. A decrease in the adverse pressure gradient near the jet orifice correlated with a momentum increase in the viscous sublayer and stronger vortical structures at the rear of the cylinder. In these same conditions, a decrease in turbulence intensity was observed in the far field wake, which is a relevant finding in the context of wind and tidal turbine arrays.

  2. Vortex Induced Vibrations of Cylinders: Experiments in Reducing Drag Force and Amplitude of Motion

    National Research Council Canada - National Science Library

    Farrell, David E

    2007-01-01

    .... The second series of tests are the rigid cylinder, PIV experiments. These rests measure both the drag force on the cylinder and the oscillating component of the lift force, the latter of which is a good indication of vortex formation. The Chapter 3 tests also image the test section wake-providing helpful insight into the physical process of vortex formations.

  3. Statistical Investigation on Coherent Vortex Structure in Turbulent Drag Reducing Channel Flow with Blown Polymer Solution

    International Nuclear Information System (INIS)

    Ishitsuka, Shota; Motozawa, Masaaki; Kawaguchi, Yasuo; Iwamoto, Kaoru; Ando, Hirotomo; Senda, Tetsuya

    2011-01-01

    Coherent vortex structure in turbulent drag-reducing channel flow with blown polymer solution from the wall was investigated. As a statistical analysis, we carried out Galilean decomposition, swirling strength and linear stochastic estimation of the PIV data obtained by the PIV measurement in x – y plane. Reynolds number based on bulk velocity and channel height was set to 40000. As a result, the angle of shear layer that cleared up by using Galilean decomposition becomes small in the drag-reducing flow. Q3 events were observed near the shear layer. In addition, as a result of linear stochastic estimation (LSE) based on swirling strength, we confirmed that the velocity under the vortex core is strong in the water flow. This result shows Q2 (ejection) are dominant in the water flow. However, in the drag-reducing flow with blown polymer solution, the velocity above the vortex core become strong, that is, Q4 (sweep) events are relatively strong around the vortex core. This is the result of Q4 events to come from the channel center region because the polymer solution does not exist in this region. The typical structure like this was observed in the drag -reducing flow with blown polymer solution from the wall.

  4. Improved Orbit Determination and Forecasts with an Assimilative Tool for Atmospheric Density and Satellite Drag Specification

    Science.gov (United States)

    Crowley, G.; Pilinski, M.; Sutton, E. K.; Codrescu, M.; Fuller-Rowell, T. J.; Matsuo, T.; Fedrizzi, M.; Solomon, S. C.; Qian, L.; Thayer, J. P.

    2016-12-01

    Much as aircraft are affected by the prevailing winds and weather conditions in which they fly, satellites are affected by the variability in density and motion of the near earth space environment. Drastic changes in the neutral density of the thermosphere, caused by geomagnetic storms or other phenomena, result in perturbations of LEO satellite motions through drag on the satellite surfaces. This can lead to difficulties in locating important satellites, temporarily losing track of satellites, and errors when predicting collisions in space. We describe ongoing work to build a comprehensive nowcast and forecast system for specifying the neutral atmospheric state related to orbital drag conditions. The system outputs include neutral density, winds, temperature, composition, and the satellite drag derived from these parameters. This modeling tool is based on several state-of-the-art coupled models of the thermosphere-ionosphere as well as several empirical models running in real-time and uses assimilative techniques to produce a thermospheric nowcast. This software will also produce 72 hour predictions of the global thermosphere-ionosphere system using the nowcast as the initial condition and using near real-time and predicted space weather data and indices as the inputs. Features of this technique include: • Satellite drag specifications with errors lower than current models • Altitude coverage up to 1000km • Background state representation using both first principles and empirical models • Assimilation of satellite drag and other datatypes • Real time capability • Ability to produce 72-hour forecasts of the atmospheric state In this paper, we will summarize the model design and assimilative architecture, and present preliminary validation results. Validation results will be presented in the context of satellite orbit errors and compared with several leading atmospheric models including the High Accuracy Satellite Drag Model, which is currently used

  5. Drag reduction and thrust generation by tangential surface motion in flow past a cylinder

    Science.gov (United States)

    Mao, Xuerui; Pearson, Emily

    2018-03-01

    Sensitivity of drag to tangential surface motion is calculated in flow past a circular cylinder in both two- and three-dimensional conditions at Reynolds number Re ≤ 1000 . The magnitude of the sensitivity maximises in the region slightly upstream of the separation points where the contour lines of spanwise vorticity are normal to the cylinder surface. A control to reduce drag can be obtained by (negatively) scaling the sensitivity. The high correlation of sensitivities of controlled and uncontrolled flow indicates that the scaled sensitivity is a good approximation of the nonlinear optimal control. It is validated through direct numerical simulations that the linear range of the steady control is much higher than the unsteady control, which synchronises the vortex shedding and induces lock-in effects. The steady control injects angular momentum into the separating boundary layer, stabilises the flow and increases the base pressure significantly. At Re=100 , when the maximum tangential motion reaches 50% of the free-stream velocity, the vortex shedding, boundary-layer separation and recirculation bubbles are eliminated and 32% of the drag is reduced. When the maximum tangential motion reaches 2.5 times of the free-stream velocity, thrust is generated and the power savings ratio, defined as the ratio of the reduced drag power to the control input power, reaches 19.6. The mechanism of drag reduction is attributed to the change of the radial gradient of spanwise vorticity (partial r \\hat{ζ } ) and the subsequent accelerated pressure recovery from the uncontrolled separation points to the rear stagnation point.

  6. Modification of Flow Structure Over a Van Model By Suction Flow Control to Reduce Aerodynamics Drag

    Directory of Open Access Journals (Sweden)

    Harinaldi Harinaldi

    2012-05-01

    Full Text Available Automobile aerodynamic studies are typically undertaken to improve safety and increase fuel efficiency as well as to  find new innovation in automobile technology to deal with the problem of energy crisis and global warming. Some car companies have the objective to develop control solutions that enable to reduce the aerodynamic drag of vehicle and  significant modification progress is still possible by reducing the mass, rolling friction or aerodynamic drag. Some flow  control method provides the possibility to modify the flow separation to reduce the development of the swirling structures around the vehicle. In this study, a family van is modeled with a modified form of Ahmed's body by changing the orientation of the flow from its original form (modified/reversed Ahmed body. This model is equipped with a suction on the rear side to comprehensively examine the pressure field modifications that occur. The investigation combines computational and experimental work. Computational approach used  a commercial software with standard k-epsilon flow turbulence model, and the objectives was  to determine the characteristics of the flow field and aerodynamic drag reduction that occurred in the test model. Experimental approach used load cell in order to validate the aerodynamic drag reduction obtained by computational approach. The results show that the application of a suction in the rear part of the van model give the effect of reducing the wake and the vortex formation. Futhermore, aerodynamic drag reduction close to 13.86% for the computational approach and 16.32% for the experimental have been obtained.

  7. Assessment of passive drag in swimming by numerical simulation and analytical procedure.

    Science.gov (United States)

    Barbosa, Tiago M; Ramos, Rui; Silva, António J; Marinho, Daniel A

    2018-03-01

    The aim was to compare the passive drag-gliding underwater by a numerical simulation and an analytical procedure. An Olympic swimmer was scanned by computer tomography and modelled gliding at a 0.75-m depth in the streamlined position. Steady-state computer fluid dynamics (CFD) analyses were performed on Fluent. A set of analytical procedures was selected concurrently. Friction drag (D f ), pressure drag (D pr ), total passive drag force (D f +pr ) and drag coefficient (C D ) were computed between 1.3 and 2.5 m · s -1 by both techniques. D f +pr ranged from 45.44 to 144.06 N with CFD, from 46.03 to 167.06 N with the analytical procedure (differences: from 1.28% to 13.77%). C D ranged between 0.698 and 0.622 by CFD, 0.657 and 0.644 by analytical procedures (differences: 0.40-6.30%). Linear regression models showed a very high association for D f +pr plotted in absolute values (R 2  = 0.98) and after log-log transformation (R 2  = 0.99). The C D also obtained a very high adjustment for both absolute (R 2  = 0.97) and log-log plots (R 2  = 0.97). The bias for the D f +pr was 8.37 N and 0.076 N after logarithmic transformation. D f represented between 15.97% and 18.82% of the D f +pr by the CFD, 14.66% and 16.21% by the analytical procedures. Therefore, despite the bias, analytical procedures offer a feasible way of gathering insight on one's hydrodynamics characteristics.

  8. Drag of Clean and Fouled Net Panels--Measurements and Parameterization of Fouling.

    Directory of Open Access Journals (Sweden)

    Lars Christian Gansel

    Full Text Available Biofouling is a serious problem in marine aquaculture and it has a number of negative impacts including increased forces on aquaculture structures and reduced water exchange across nets. This in turn affects the behavior of fish cages in waves and currents and has an impact on the water volume and quality inside net pens. Even though these negative effects are acknowledged by the research community and governmental institutions, there is limited knowledge about fouling related effects on the flow past nets, and more detailed investigations distinguishing between different fouling types have been called for. This study evaluates the effect of hydroids, an important fouling organism in Norwegian aquaculture, on the forces acting on net panels. Drag forces on clean and fouled nets were measured in a flume tank, and net solidity including effect of fouling were determined using image analysis. The relationship between net solidity and drag was assessed, and it was found that a solidity increase due to hydroids caused less additional drag than a similar increase caused by change in clean net parameters. For solidities tested in this study, the difference in drag force increase could be as high as 43% between fouled and clean nets with same solidity. The relationship between solidity and drag force is well described by exponential functions for clean as well as for fouled nets. A method is proposed to parameterize the effect of fouling in terms of an increase in net solidity. This allows existing numerical methods developed for clean nets to be used to model the effects of biofouling on nets. Measurements with other types of fouling can be added to build a database on effects of the accumulation of different fouling organisms on aquaculture nets.

  9. Effects of tritium-labeled pyrimidine nucleosides on epithelial cell proliferation in the mouse. I. Cytodynamic perturbations in normal circadian rhythms after a single injection of 3H-thymidine

    International Nuclear Information System (INIS)

    Olsson, L.

    1976-01-01

    In a combined stathmokinetic, autoradiographic, and microspectrophotometric study on the cytodynamics in mouse epidermis, cirdardian rhythms were observed in the number of cells within the various phases (except G 2 ) of the mitotic cell cycle, and in mitotic rate. S-Phase influx and efflux were computed and were found to vary during a 24-hr period. No diurnal rhythm was observed in mitotic rate in the epithelium of small intestine. 3 H-Thymidine (1 μCi/g; sp act 5 Ci/mmol) induced mitotic delay in labeled cells 2 to 8 hr after administration. A supranormal mitotic activity in unlabeled cells was observed 12 to 24 hr after injection of 3 H-TdR. ''Cold'' thymidine had no effects on epidermal cell proliferation. S-Phase duration and average cell cycle time were estimated by traditional cell kinetic methods. The results suggest a 3 H-TdR-induced synchrony in cells entering the S phase 0 to 15 hr after injection of the precursor. A mitotic delay was seen in small intestinal epithelium 2 to 6 hr after injection of the precursor

  10. Immunologic analyses of mouse cystathionase in normal and leukemic cells

    International Nuclear Information System (INIS)

    Bikel, I.; Faibes, D.; Uren, J.R.; Livingston, D.M.

    1978-01-01

    Rabbit antisera have been raised against mouse liver cystathionase and shown to possess enzyme neutralizing activity. Agar gel double immunodiffusion analyses demonstrated that both mouse liver cystathionase and rat liver cystathionase react with the antisera, the latter enzyme being completely cross-reactive with the former. Following radioiodination of the purified rat liver enzyme, a double antibody radioimmunoassay was developed in which greater than 90% of the labeled protein could be specifically precipitated with the anti-mouse cystathionase antibodies. In this test the purified rat liver and mouse liver enzymes were virtually indistinguishable, generating superimposable competition displacement curves on a protein mass basis. These results indicate that both enzymes are immunologically identical, thus validating the use of the rat in lieu of the murine liver enzyme as radiolabeled tracer in an assay for mouse cystathionase. In addition, competition radioimmunoassays demonstrated that the immunological reactivities of both the purified rat liver and mouse liver enzymes were equally heat sensitive. The sensitivity of the assay was determined to be 1 ng of enzyme protein/0.22 mL of assay mixture, and the assay could be used to detect the presence of enzyme protein in tissue homogenates of single mouse organs. Mouse or rat cross-reactivity with human liver cystathionase was incomplete; but, with the exception of heart and spleen, parallel radioimmunoassay competition displacement curves were obtained for cystathionase from different mouse organs including thymus. Extracts of 7-, 9-, and 10-month-old spontaneous AKR mouse thymomas were tested in the radioimmunoassay along with extracts of age-matched thymuses which were grossly tumor free. A reaction of nonidentity was observed for all of the tumor extracts while a reaction identical with that of the pure liver enzyme was found with all of the normal thymus extracts

  11. Colonization, mouse-style

    Directory of Open Access Journals (Sweden)

    Searle Jeremy B

    2010-10-01

    Full Text Available Abstract Several recent papers, including one in BMC Evolutionary Biology, examine the colonization history of house mice. As well as background for the analysis of mouse adaptation, such studies offer a perspective on the history of movements of the humans that accidentally transported the mice. See research article: http://www.biomedcentral.com/1471-2148/10/325

  12. Small-scale orographic gravity wave drag in stable boundary layers and its impact on synoptic systems and near surface meteorology

    NARCIS (Netherlands)

    Tsiringakis, Aristofanis; Steeneveld, G.J.; Holtslag, A.A.M.

    2017-01-01

    At present atmospheric models for weather and climate use enhanced turbulent drag under stable conditions, because these empirically provide the necessary momentum drag for accurate forecast of synoptic systems. The enhanced mixing (also known as the "long-tail"), introduces drag that can not be

  13. Numerical study of water entry supercavitating flow around a vertical circular cylinder influenced by turbulent drag-reducing additives

    International Nuclear Information System (INIS)

    Jiang, C X; Cheng, J P; Li, F C

    2015-01-01

    This paper attempts to introduce a numerical simulation procedure to simulate water-entry problems influenced by turbulent drag-reducing additives in a viscous incompressible medium. Firstly we performed a numerical investigation on water-entry supercavities in water and turbulent drag-reducing solution at the impact velocity of 28.4 m/s to confirm the accuracy of the numerical method. Based on the verification, projectile entering water and turbulent drag-reducing solution at relatively high velocity of 142.7 m/s (phase transition is considered) is simulated. The cross viscosity equation was adopted to represent the shear-thinning characteristic of aqueous solution of drag-reducing additives. The configuration and dynamic characteristics of water entry supercavity, flow resistance were discussed respectively. It was obtained that the numerical simulation results are in consistence with experimental data. Numerical results show that the supercavity length in drag-reducing solution is larger than one in water and the velocity attenuates faster at high velocity than at low velocity; the influence of drag-reducing solution is more obvious at high impact velocity. Turbulent drag-reducing additives have the great potential for enhancement of supercavity

  14. A unified viscous theory of lift and drag of 2-D thin airfoils and 3-D thin wings

    Science.gov (United States)

    Yates, John E.

    1991-01-01

    A unified viscous theory of 2-D thin airfoils and 3-D thin wings is developed with numerical examples. The viscous theory of the load distribution is unique and tends to the classical inviscid result with Kutta condition in the high Reynolds number limit. A new theory of 2-D section induced drag is introduced with specific applications to three cases of interest: (1) constant angle of attack; (2) parabolic camber; and (3) a flapped airfoil. The first case is also extended to a profiled leading edge foil. The well-known drag due to absence of leading edge suction is derived from the viscous theory. It is independent of Reynolds number for zero thickness and varies inversely with the square root of the Reynolds number based on the leading edge radius for profiled sections. The role of turbulence in the section induced drag problem is discussed. A theory of minimum section induced drag is derived and applied. For low Reynolds number the minimum drag load tends to the constant angle of attack solution and for high Reynolds number to an approximation of the parabolic camber solution. The parabolic camber section induced drag is about 4 percent greater than the ideal minimum at high Reynolds number. Two new concepts, the viscous induced drag angle and the viscous induced separation potential are introduced. The separation potential is calculated for three 2-D cases and for a 3-D rectangular wing. The potential is calculated with input from a standard doublet lattice wing code without recourse to any boundary layer calculations. Separation is indicated in regions where it is observed experimentally. The classical induced drag is recovered in the 3-D high Reynolds number limit with an additional contribution that is Reynold number dependent. The 3-D viscous theory of minimum induced drag yields an equation for the optimal spanwise and chordwise load distribution. The design of optimal wing tip planforms and camber distributions is possible with the viscous 3-D wing theory.

  15. Drag reduction in reservoir rock surface: Hydrophobic modification by SiO{sub 2} nanofluids

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Yong-Li, E-mail: yylhill@163.com [College of Chemistry & Chemical Engineering, Xi’an Shiyou University, Xi’an 710065 (China); Cui, Ming-Yue; Jiang, Wei-Dong; He, An-Le; Liang, Chong [Langfang Branch of Research Institute of Petroleum Exploration & Development, Langfang 065007 (China)

    2017-02-28

    Graphical abstract: The micro-nanoscale hierarchical structures at the sandstone core surface are constructed by adsorption of the modified silica nanoparticles, which leads to the effect of drag reduction to improve the low injection rate in ultra-low permeability reservoirs. - Highlights: • A micro-nanoscale hierarchical structure is formed at the reservoir rock surface. • An inversion has happened from hydrophilic into hydrophobic modified by nanofluids. • The effect of drag reduction to improve the low injection rate is realized. • The mechanism of drag reduction induced from the modified core surface was unclosed. - Abstract: Based on the adsorption behavior of modified silica nanoparticles in the sandstone core surface, the hydrophobic surface was constructed, which consists of micro-nanoscale hierarchical structure. This modified core surface presents a property of drag reduction and meets the challenge of high injection pressure and low injection rate in low or ultra-low permeability reservoir. The modification effects on the surface of silica nanoparticles and reservoir cores, mainly concerning hydrophobicity and fine structure, were determined by measurements of contact angle and scanning electron microscopy. Experimental results indicate that after successful modification, the contact angle of silica nanoparticles varies from 19.5° to 141.7°, exhibiting remarkable hydrophobic properties. These modified hydrophobic silica nanoparticles display a good adsorption behavior at the core surface to form micro-nanobinary structure. As for the wettability of these modified core surfaces, a reversal has happened from hydrophilic into hydrophobic and its contact angle increases from 59.1° to 105.9°. The core displacement experiments show that the relative permeability for water has significantly increased by an average of 40.3% via core surface modification, with the effects of reducing injection pressure and improving injection performance of water

  16. Drag reduction in reservoir rock surface: Hydrophobic modification by SiO_2 nanofluids

    International Nuclear Information System (INIS)

    Yan, Yong-Li; Cui, Ming-Yue; Jiang, Wei-Dong; He, An-Le; Liang, Chong

    2017-01-01

    Graphical abstract: The micro-nanoscale hierarchical structures at the sandstone core surface are constructed by adsorption of the modified silica nanoparticles, which leads to the effect of drag reduction to improve the low injection rate in ultra-low permeability reservoirs. - Highlights: • A micro-nanoscale hierarchical structure is formed at the reservoir rock surface. • An inversion has happened from hydrophilic into hydrophobic modified by nanofluids. • The effect of drag reduction to improve the low injection rate is realized. • The mechanism of drag reduction induced from the modified core surface was unclosed. - Abstract: Based on the adsorption behavior of modified silica nanoparticles in the sandstone core surface, the hydrophobic surface was constructed, which consists of micro-nanoscale hierarchical structure. This modified core surface presents a property of drag reduction and meets the challenge of high injection pressure and low injection rate in low or ultra-low permeability reservoir. The modification effects on the surface of silica nanoparticles and reservoir cores, mainly concerning hydrophobicity and fine structure, were determined by measurements of contact angle and scanning electron microscopy. Experimental results indicate that after successful modification, the contact angle of silica nanoparticles varies from 19.5° to 141.7°, exhibiting remarkable hydrophobic properties. These modified hydrophobic silica nanoparticles display a good adsorption behavior at the core surface to form micro-nanobinary structure. As for the wettability of these modified core surfaces, a reversal has happened from hydrophilic into hydrophobic and its contact angle increases from 59.1° to 105.9°. The core displacement experiments show that the relative permeability for water has significantly increased by an average of 40.3% via core surface modification, with the effects of reducing injection pressure and improving injection performance of water

  17. A Data-Driven Approach to Develop Physically Sound Predictors: Application to Depth-Averaged Velocities and Drag Coefficients on Vegetated Flows

    Science.gov (United States)

    Tinoco, R. O.; Goldstein, E. B.; Coco, G.

    2016-12-01

    We use a machine learning approach to seek accurate, physically sound predictors, to estimate two relevant flow parameters for open-channel vegetated flows: mean velocities and drag coefficients. A genetic programming algorithm is used to find a robust relationship between properties of the vegetation and flow parameters. We use data published from several laboratory experiments covering a broad range of conditions to obtain: a) in the case of mean flow, an equation that matches the accuracy of other predictors from recent literature while showing a less complex structure, and b) for drag coefficients, a predictor that relies on both single element and array parameters. We investigate different criteria for dataset size and data selection to evaluate their impact on the resulting predictor, as well as simple strategies to obtain only dimensionally consistent equations, and avoid the need for dimensional coefficients. The results show that a proper methodology can deliver physically sound models representative of the processes involved, such that genetic programming and machine learning techniques can be used as powerful tools to study complicated phenomena and develop not only purely empirical, but "hybrid" models, coupling results from machine learning methodologies into physics-based models.

  18. The Effect of Air Drag in Optimal Power-Limited Rendezvous Between Coplanar Low-Earth Orbits

    Directory of Open Access Journals (Sweden)

    Gil-Young Maeng

    1998-06-01

    Full Text Available The effect of air drag was researched when a low-earth orbit spacecraft using power-limited thruster rendezvoused another low-earth orbit spacecraft. The air density was assumed to decrease exponentially. The radius of parking orbit was 6655.935 km and that of target orbit was 7321.529 km. From the trajectories of active vehicles, the fuel consumption and the magnitude of thrust acceleration, we could conclude that the effect of air drag had to be considered in fuel optimal rendezvous problem between low-earth orbit spacecrafts. In multiple-revolution rendezvous case, the air drag was more effective.

  19. Surface correlations of hydrodynamic drag for transitionally rough engineering surfaces

    Science.gov (United States)

    Thakkar, Manan; Busse, Angela; Sandham, Neil

    2017-02-01

    Rough surfaces are usually characterised by a single equivalent sand-grain roughness height scale that typically needs to be determined from laboratory experiments. Recently, this method has been complemented by a direct numerical simulation approach, whereby representative surfaces can be scanned and the roughness effects computed over a range of Reynolds number. This development raises the prospect over the coming years of having enough data for different types of rough surfaces to be able to relate surface characteristics to roughness effects, such as the roughness function that quantifies the downward displacement of the logarithmic law of the wall. In the present contribution, we use simulation data for 17 irregular surfaces at the same friction Reynolds number, for which they are in the transitionally rough regime. All surfaces are scaled to the same physical roughness height. Mean streamwise velocity profiles show a wide range of roughness function values, while the velocity defect profiles show a good collapse. Profile peaks of the turbulent kinetic energy also vary depending on the surface. We then consider which surface properties are important and how new properties can be incorporated into an empirical model, the accuracy of which can then be tested. Optimised models with several roughness parameters are systematically developed for the roughness function and profile peak turbulent kinetic energy. In determining the roughness function, besides the known parameters of solidity (or frontal area ratio) and skewness, it is shown that the streamwise correlation length and the root-mean-square roughness height are also significant. The peak turbulent kinetic energy is determined by the skewness and root-mean-square roughness height, along with the mean forward-facing surface angle and spanwise effective slope. The results suggest feasibility of relating rough-wall flow properties (throughout the range from hydrodynamically smooth to fully rough) to surface

  20. Characteristics of the mouse genomic histamine H1 receptor gene

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Isao; Taniuchi, Ichiro; Kitamura, Daisuke [Kyushu Univ., Fukuoka (Japan)] [and others

    1996-08-15

    We report here the molecular cloning of a mouse histamine H1 receptor gene. The protein deduced from the nucleotide sequence is composed of 488 amino acid residues with characteristic properties of GTP binding protein-coupled receptors. Our results suggest that the mouse histamine H1 receptor gene is a single locus, and no related sequences were detected. Interspecific backcross analysis indicated that the mouse histamine H1 receptor gene (Hrh1) is located in the central region of mouse Chromosome 6 linked to microphthalmia (Mitfmi), ras-related fibrosarcoma oncogene 1 (Raf1), and ret proto-oncogene (Ret) in a region of homology with human chromosome 3p. 12 refs., 3 figs.