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Sample records for single meandering channel

  1. Laboratory Experiments on Meandering Meltwater Channels

    Science.gov (United States)

    Fernandez, R.; Berens, J.; Parker, G.; Stark, C. P.

    2017-12-01

    Meandering channels of all scales and flowing over a wide variety of media have common planform patterns. Although the analogy in planform suggests there is a common underlying framework, the constitutive relations driving planform evolution through vertical incision/deposition and lateral migration differ from medium to medium. The driving processes in alluvial and mixed bedrock-alluvial meandering channels have been studied substantially over the last decades. However, this is not the case for meandering channels in other media such as ice or soluble rock. Here we present results from experiments conducted at the Ven Te Chow Hydrosystems Laboratory of the University of Illinois at Urbana-Champaign on meltwater meandering channels. A rivulet is carved into an ice block and water is allowed to flow at a constant discharge. Planform evolution is analyzed with time lapse imaging and complemented with rubber molds of the channel once the experiment is over. These molds give us the full 3D structure of the meandering, including incisional overhang. Vertical incision rates are measured throughout the run by taking elevations along the channel, and these measurements are complemented with analysis from the molds. We show examples of meandering of intense amplitude with deep overhangs. Features resembling scroll bars document cyclically punctuated melting. We report on lateral migration rates, incision rates, sinuosity, channel depths, channel widths, reach averaged velocities, bend wavelengths and amplitudes and compare them to values reported in the literature for alluvial rivers.

  2. Analytical Prediction Of Meandering Channel Evolution

    Science.gov (United States)

    Chen, D.; Duan, J. G.

    2003-12-01

    The evolution of meandering channels, as a complex phenomenon, has been the research subject challenging river engineers for decades. The evolution of meandering channels is a complex morph-dynamic process resulted from the interaction among flow, sediment, and bank material. The rate of bank erosion was conventionally assumed to be proportional to the magnitude of near-bank excessive velocity or shear stress. A number of laboratory experiments on mild curved channels of flat beds indicated that the high velocity zone crosses the channel centerline at the neighborhood of the downstream inflection point instead of immediately downstream of the apex. If bank erosion only occurs at the places of high shear stress, the erosion of convex banks should be observed in these laboratory flumes, and the bends tend to subside. However, numerous experiments proved that a moderately or highly sinuous channel was initiated from a straight or mildly curved channel of no transverse slope by eroding the concave banks. Obviously

  3. River channel patterns: Braided, meandering, and straight

    Science.gov (United States)

    Leopold, Luna Bergere; Wolman, M. Gordon

    1957-01-01

    Channel pattern is used to describe the plan view of a reach of river as seen from an airplane, and includes meandering, braiding, or relatively straight channels.Natural channels characteristically exhibit alternating pools or deep reaches and riffles or shallow reaches, regardless of the type of pattern. The length of the pool or distance between riffles in a straight channel equals the straight line distance between successive points of inflection in the wave pattern of a meandering river of the same width. The points of inflection are also shallow points and correspond to riffles in the straight channel. This distance, which is half the wavelength of the meander, varies approximately as a linear function of channel width. In the data we analysed the meander wavelength, or twice the distance between successive riffles, is from 7 to 12 times the channel width. It is concluded that the mechanics which may lead to meandering operate in straight channels.River braiding is characterized by channel division around alluvial islands. The growth of an island begins as the deposition of a central bar which results from sorting and deposition of the coarser fractions of the load which locally cannot be transported. The bar grows downstream and in height by continued deposition on its surface, forcing the water into the flanking channels, which, to carry the flow, deepen and cut laterally into the original banks. Such deepening locally lowers the water surface and the central bar emerges as an island which becomes stabilized by vegetation. Braiding was observed in a small river in a laboratory. Measurements of the adjustments of velocity, depth, width, and slope associated with island development lead to the conclusion that braiding is one of the many patterns which can maintain quasi-equilibrium among discharge, load, and transporting ability. Braiding does not necessarily indicate an excess of total load.Channel cross section and pattern are ultimately controlled by the

  4. Methodology for calculating shear stress in a meandering channel

    Science.gov (United States)

    Kyung-Seop Sin

    2010-01-01

    Shear stress in meandering channels is the key parameter to predict bank erosion and bend migration. A representative study reach of the Rio Grande River in central New Mexico has been modeled in the Hydraulics Laboratory at CSU. To determine the shear stress distribution in a meandering channel, the large scale (1:12) physical modeling study was conducted in the...

  5. Influence of Meander Confinement on Hydro-Morphodynamics of a Cohesive Meandering Channel

    Directory of Open Access Journals (Sweden)

    Parna Parsapour-Moghaddam

    2018-03-01

    Full Text Available Despite several decades of intensive study of the morphological changes in meandering rivers, less attention has been paid to confined meanders. This paper studies the hydro-morphodynamics of two adjacent sub-reaches of a meandering creek, located in the City of Ottawa, Canada. Both of these sub-reaches are meandering channels with cohesive bed and banks, but one is confined by a railway embankment. Field reconnaissance revealed distinct differences in the morphological characteristics of the sub-reaches. To further study this, channel migration and morphological changes of the channel banks along each of these sub-reaches were analyzed by comparing the historical aerial photography (2004, 2014, light detection and ranging (LIDAR data (2006, bathymetric data obtained from a total station survey (2014, and field examination. Moreover, two different spatially intensive acoustic Doppler current profiler (ADCP surveys were conducted in the study area to find the linkage between the hydrodynamics and morphological changes in the two different sub-reaches. The unconfined sub-reach is shown to have a typical channel migration pattern with deposition on the inner bank and erosion on the outer bank of the meander bend. The confined sub-reach, on the other hand, experienced greater bank instabilities than the unconfined sub-reach. The average rate of bank retreat was 0.2 m/year in the confined sub-reach whereas it was lower (0.08 m/year in the unconfined sampling reach. In the confined sub-reach, an irregular meandering pattern occurred by the evolution of a concave-bank bench, which was caused by reverse flow eddies. The sinuosity of the confined sub-reach decreased from 1.55 to 1.49 in the 10-year study period. The results of the present study demonstrate the physical mechanisms by which meander confinement can change the meandering pattern and morphological characteristics of a cohesive clay bed creek.

  6. Computer simulations of channel meandering and the formation of point bars: Linking channel dynamics to the preserved stratigraphy

    Science.gov (United States)

    Sun, T.; Covault, J. A.; Pyrcz, M.; Sullivan, M.

    2012-12-01

    a,b) is used to investigate the formation and preservation of point bars with meandering rivers. Rather than consisting of a single set of concentric scroll bar like feature as one would expect from the pattern of meandering channels, observations of point bar deposits in map view reveal the previously mentioned complexity in their internal organization. A preserved point bar deposit is often found to be composed of multiple sets of remnant scroll bar like features, each with different orientations. Each set is bounded by the unconformity resulting from one set of the scroll bar like feature truncated by the other set. This study links the channel dynamics to the preserved point bar architectures, and delineates the key controls that affect the point bar internal organization.

  7. Multi-channeled NbN superconducting single photon detectors (SSPDs) system with NbN meander nanowires

    International Nuclear Information System (INIS)

    Fujiwara, Mikio; Sasaki, Masahide; Miki, Shigehito; Wang Zhen

    2009-01-01

    A superconducting single photon detector (SSPD) is promising candidate of the detector in a quantum key distribution (QKD) system, because of its low dark count and high speed repetition rate. We have developed the SSPD system cooled by a GM cryocooler. In this system, and the work surface can be cooled 2.95 K and up to 6 SSPDs can be installed. The active areas of SSPDs are 10x10 μm 2 or 20x20 μm 2 , and the system detection efficiency at dark count rate of 100 Hz reached 2.6% at a wavelength of 1550 nm.

  8. Channel Restoration Design for Meandering Rivers

    National Research Council Canada - National Science Library

    Soar, Philip

    2001-01-01

    A framework for channel restoration design is presented that attempts to bridge the divide between reconnaissance level geomorphological designs at one extreme and numerical modeling of hydrodynamics...

  9. 2D numerical modelling of meandering channel formation

    Science.gov (United States)

    XIAO, Y.; ZHOU, G.; YANG, F. S.

    2016-03-01

    A 2D depth-averaged model for hydrodynamic sediment transport and river morphological adjustment was established. The sediment transport submodel takes into account the influence of non-uniform sediment with bed surface armoring and considers the impact of secondary flow in the direction of bed-load transport and transverse slope of the river bed. The bank erosion submodel incorporates a simple simulation method for updating bank geometry during either degradational or aggradational bed evolution. Comparison of the results obtained by the extended model with experimental and field data, and numerical predictions validate that the proposed model can simulate grain sorting in river bends and duplicate the characteristics of meandering river and its development. The results illustrate that by using its control factors, the improved numerical model can be applied to simulate channel evolution under different scenarios and improve understanding of patterning processes.

  10. Flow structure and channel morphology at a natural confluent meander bend

    Science.gov (United States)

    Riley, James D.; Rhoads, Bruce L.

    2012-08-01

    Previous experimental, field, and modeling studies of confluence dynamics have focused mainly on junctions formed by straight channels. In contrast, natural rivers often meander and tributaries can enter meandering rivers on the outside of bends to form a junction planform known as a confluent meander bend. In this study, field measurements of three-dimensional velocity components and bed topography at a confluent meander bend reveal a complex hydrodynamic environment that responds to changes in momentum-flux ratio, while channel morphology remains relatively stable. Flow from the tributary deflects high-velocity flow and helical motion in the curving main river toward the inside of the bend, inducing bed scour and inhibiting point-bar development. The high junction angle forces the tributary flow to abruptly realign to the orientation of the downstream channel, initiating a counter-rotating helical cell over the outer portion of the bend. Two surface-convergent helical cells persist through the downstream channel, where the combined flows accelerate as the channel cross-sectional area is constricted by a bar along the downstream junction corner, precluding flow separation. Long-term stability of its planform suggests that this confluent meander bend represents a quasi-stable channel configuration. Overall, patterns of flow and channel morphology are quite different from typical patterns in most meander bends, but are generally consistent with a conceptual model of confluent meander bends derived from previous laboratory experiments and numerical modeling.

  11. Modeling Flow Pattern and Evolution of Meandering Channels with a Nonlinear Model

    Directory of Open Access Journals (Sweden)

    Leilei Gu

    2016-09-01

    Full Text Available Meander dynamics has been the focus of river engineering for decades; however, it remains a challenge for researchers to precisely replicate natural evolution processes of meandering channels with numerical models due to the high nonlinearity of the governing equations. The present study puts forward a nonlinear model to simulate the flow pattern and evolution of meandering channels. The proposed meander model adopts the nonlinear hydrodynamic submodel developed by Blanckaert and de Vriend, which accounts for the nonlinear interactions between secondary flow and main flow and therefore has no curvature restriction. With the computational flow field, the evolution process of the channel centerline is simulated using the Bank Erosion and Retreat Model (BERM developed by Chen and Duan. Verification against two laboratory flume experiments indicates the proposed meander model yields satisfactory agreement with the measured data. For comparison, the same experimental cases are also simulated with the linear version of the hydrodynamic submodel. Calculated results show that the flow pattern and meander evolution process predicted by the nonlinear and the linear models are similar for mildly curved channels, whereas they exhibit different characteristics when channel sinuosity becomes relatively high. It is indicated that the nonlinear interactions between main flow and secondary flow prevent the growth of the secondary flow and induce a more uniform transverse velocity profile in high-sinuosity channels, which slows down the evolution process of meandering channels.

  12. 2D numerical modelling of meandering channel formation

    Indian Academy of Sciences (India)

    . 4.1 Influence of bank geometry for meander bends. Bank erosion processes involve the complex inter- action of flow field, bank material, and bank geom- etry. The retreat length ΔBc depends on bank size, shape and materials, determined by ...

  13. Optical remote sensing of bedforms in a field-scale meandering channel

    Science.gov (United States)

    Palmsten, M. L.; Kozarek, J. L.; Calantoni, J.

    2012-12-01

    The morphology and migration rate of bedforms in a sandy meander vary as a result of differences in boundary shear stress around the meander bend. The objective of this work is to quantify bedform size and migration rate using synoptic observations of remotely sensed water depth around a meander bend. We conducted an experiment from 9-20 July 2012 at the Saint Anthony Falls Laboratory Outdoor StreamLab (OSL), University of Minnesota. The OSL consists of a bedload dominated, sandy (D50 = 0.7 mm) meandering channel approximately 40 m in length, 2.7 m in width, and 0.3 m in depth. Riffles were installed upstream and downstream of the meander bend. Discharge was fixed at 199 L/s throughout the experiment and sediment feed rate was 4.1 kg/min. Four color video cameras were mounted on a tower 5 m above the floodplain on the inner bank of the meander looking down into the stream. Two additional cameras, including one near infra-red camera were mounted on the outer bank of the meander. Video data were supplemented by 1 mm resolution measurements of velocity and sonar observations of bed elevation. The sonar and video data were used to create a transfer function between pixel intensity and water depth and pixel location was corrected for refraction, resulting ~0.01 m resolution depth measurements along the entire meander bend. Initially, the stream bed was flat. A pool formed immediately downstream of the riffle. A point bar and ripples developed during the first hour of the experiment. The morphology of bedforms changed with position around the meander bend from convex upstream to convex downstream. The sinuosity of bedforms also increased around the meander bend, reaching maximum near the bend apex. Bedform wavelength increased around the meander bend from 0.5 m upstream of the bend apex to > 1.5 m downstream of the bed apex. Bedform spacing increased as alternating bedforms increased in amplitude while neighboring bedforms decreased in amplitude until they disappeared

  14. Bar and channel evolution in meandering and braiding rivers using physics-based modeling

    NARCIS (Netherlands)

    Schuurman, F.

    2015-01-01

    Rivers are among the most dynamic earth surface systems. Some rivers meander, forming bends that migrate, reshape and have inner-bend bars. Other rivers form a complicated braided pattern of branches, islands and mid-channel bars. Thorough understanding of their morphodynamics is important for

  15. Flow structure and channel morphodynamics of meander bend chute cutoffs: A case study of the Wabash River, USA

    Science.gov (United States)

    Zinger, Jessica A.; Rhoads, Bruce L.; Best, James L.; Johnson, Kevin K.

    2013-12-01

    paper documents the three-dimensional structure of flow and bed morphology of two developing chute cutoffs on a single meander bend on the lower Wabash River, USA, and relates the flow structure to patterns of morphologic change in the evolving cutoff channels. The upstream end of the cutoff channels is characterized by: (1) a zone of flow velocity reduction/stagnation and bar development in the main channel across from the cutoff entrance, (2) flow separation and bar development along the inner (left) bank of the cutoff channel immediately downstream from the cutoff entrance, and (3) helical motion and outward advection of flow momentum entering the cutoff channel, leading to erosion of the outer (right) bank of the cutoff channel. At the downstream end of the cutoff channels, the major hydrodynamic and morphologic features are: (1) flow stagnation along the bank of the main channel immediately upstream of the cutoff channel mouth, (2) convergence of flows from the cutoff and main channels, (3) helical motion of flow from the cutoff, (4) a zone of reduced velocity along the bank of the main channel immediately downstream from the cutoff channel mouth, and (5) development of a prominent bar complex that penetrates into the main channel and extends from the stagnation zone upstream to downstream of the cutoff mouth. These results provide the basis for a conceptual model of chute-cutoff dynamics in which the upstream and downstream ends of a cutoff channel are treated as a bifurcation and confluence, respectively.

  16. Transposition of a Process-Based Model, Flumy: from Meandering Fluvial Systems to Channelized Turbidite Systems

    Science.gov (United States)

    Lemay, M.; Cojan, I.; Rivoirard, J.; Grimaud, J. L.; Ors, F.

    2017-12-01

    Channelized turbidite systems are among the most important hydrocarbon reservoirs. Yet building realistic turbidite reservoir models is still a challenge. Flumy has been firstly developed to simulate the long-term evolution of aggrading meandering fluvial systems in order to build facies reservoir models. In this study, Flumy has been transposed to channelized turbidite systems. The channel migration linear model of Imran et al. (1999) dedicated to subaqueous flows has been implemented. The whole model has been calibrated taking into account the differences on channel morphology, avulsion frequency, and aggradation and migration rates. This calibration and the comparison of the model to natural systems rely on: i) the channel planform morphology characterized by the meander wavelength, amplitude, and sinuosity; ii) the channel trajectory and the resulting stratigraphic architecture described using Jobe et al. (2016) indexes. Flumy succeeds in reproducing turbidite channel planform morphology as shown by the mean sinuosity of 1.7, the wavelength to width and amplitude to width ratios around 4 and 1 respectively. First-order meander architecture, characterized by the ratios meander belt width versus channel width, meander belt thickness versus channel depth, and the deduced stratigraphic mobility number (the ratio between lateral versus vertical channel displacements), is also well reproduced: 2.5, 3.8, and 0.6 respectively. Both lateral and downstream channel normalized migrations are around 3.5 times lower than in fluvial systems. All these values are absolutely coherent with the observations. In the other hand, the channel trajectory observed on seismic cross sections (hockey stick geometry) is not fully reproduced: the local stratigraphic mobility number is divided upward by 3 whereas up to 10 is expected. This behavior is generally explained in the literature by an increasing aggradation rate through time and/or flow stripping at outer bend that decreases

  17. River Restoration and Meanders

    Directory of Open Access Journals (Sweden)

    G. Mathias Kondolf

    2006-12-01

    Full Text Available Among the most visually striking river restoration projects are those that involve the creation of a new channel, often in a new alignment and generally with a form and dimensions that are different from those of the preproject channel. These channel reconstruction projects often have the objective of creating a stable, single-thread, meandering channel, even on rivers that were not historically meandering, on rivers whose sediment load and flow regime would not be consistent with such stable channels, or on already sinuous channels whose bends are not symmetrical. Such meandering channels are often specified by the Rosgen classification system, a popular restoration design approach. Although most projects of this type have not been subject to objective evaluation, completed postproject appraisals show that many of these projects failed within months or years of construction. Despite its, at best, mixed results, this classification and form-based approach continues to be popular because it is easy to apply, because it is accessible to those without formal training in fluvial geomorphology, and probably because it satisfies a deep-seated, although unrecognized, cultural preference for single-thread meandering channels. This preference is consistent with 18th-century English landscape theories, which held the serpentine form to be ideal and led to widespread construction of meandering channels on the country estates of the era. The preference for stability in restored channels seems to be widely accepted by practitioners and funders despite the fact that it is antithetical to research showing that dynamically migrating channels have the greatest ecological richness.

  18. Methodology for calculating shear stress in a meandering channel

    Science.gov (United States)

    Kyung-Seop Sin; Christopher I. Thornton; Amanda L. Cox; Steven R. Abt

    2012-01-01

    Natural channels never stop changing their geomorphic characteristics. Natural alluvial streams are similar to living creatures because they generate water flow, develop point bars, alter bed profile, scour the bed, erode the bank, and cause other phenomena in the stream system. The geomorphic changes in a natural system lead to a wide array of research worldwide,...

  19. 2D numerical modelling of meandering channel formation

    Indian Academy of Sciences (India)

    To simulate the bend development and lateral migration of alluvial channels, a 2D numerical model must account for bend flow effects and river bank erosion processes. Subsequent works on helical flow and forces on sed- iment grains on a transversely sloping bed (e.g.,. Einstein and Shen 1964; Engelund 1974; Bathurst.

  20. Photogrammetric survey to measure the bed topography of a laboratory large amplitude meandering channel

    Science.gov (United States)

    Lo Brutto, Mauro

    2010-05-01

    One of the main characteristics of the rivers that exhibit a meandering planform is the continuous evolution of the planimetric shape. In order to limit flooding risks and to control the ecological equilibrium of the areas neighboring the channel, it is important to define a forecast methodology of the channel evolution. The pattern of the channel evolution strongly depends on the configuration of the "stable" bed topography along the channel in every stage of the evolution itself. Previous works [Schumm, 1963; Schumm, 1972; Jackson, 1975; Hooke, 1976; Ren and Jun, 1989; Whiting and Dietrich, 1993] show that the localization of the erosion and deposition zones along the channel is not standard but it depends on the planimetric shape of the channel itself. For example, it was shown that at the early stage of a meander wave evolution (small value of deflection angle J0) the deepest erosion of the bed is localized at the inner bank between the sections corresponding respectively to the inflection point and to the apex of the bend. In channels with "large" sinuosity (large value of deflection angle J0) the deepest erosion is localized in the outer bank near the apex of the bend [Yalin, 1992]. Recently, da Silva et al. [2006] verified that every different sinuosity (every J0) has its own convective flow pattern and, as previously observed in a large amplitude meandering channel by Termini (1996), the knowledge of the convective structure of the depth-averaged "initial" (determined at t=0 with flat bed) flow, which is associated only to changing channel curvature, can be used to predict the general features of bed topography. Thus, the knowledge of the stable bed topography is important to predict the channel planimetric evolution. In this paper the equilibrium bed topography determined in a large meandering laboratory channel has been first measured by a using a profile indicator PV09 by Delft Hydraulics (precision of 0.1 mm). The PV09 is designed to maintain a constant

  1. Hydraulic interactions between a meandering river channel and its floodplain during an overbank flood

    Science.gov (United States)

    Harrison, L.; Dunne, T.; Fisher, B.

    2012-12-01

    River channel and floodplain complexity is generated by the lateral migration of meandering river channels across the floodplain surface. The main driver of meander migration is the flow field which erodes the outer bank of river bends, scours pools, creates topographic variability on the floodplain and interacts with riparian vegetation. Flows between channels and floodplains are generally thought to be highly three-dimensional due to the presence of secondary circulation cells and helical flow patterns observed in laboratory experiments, yet few field datasets exist to test or validate existing conceptual models. Flow over and through floodplain vegetation has also been difficult to characterize at the field scale. We took advantage of a remarkably long and stable 5-year flood discharge to measure flow fields across the floodplain and in curved reaches of the gravel-bed Merced River In California to document the hydraulic interactions between the channel and floodplain. We then developed, calibrated and validated a quasi-3D hydrodynamic model of the flows in order to expand the interpretation of the results. Due to the spatial variability in both topography and flow resistance, the modeling required detailed mapping of the channel-floodplain surface and vegetation with a terrestrial LiDAR scanner and RTK GPS units. The results highlight several general aspects of the channel-floodplain flow during an overbank flow event: (1) the flow field in the channel was largely two-dimensional with only weak helical flow patterns; (2) the highest channel velocities and boundary shear stresses occurred at the local maxima in bend curvature where lateral migration has been documented via repeat topographic surveys; (3) flow velocities rapidly decelerated as water was decanted from the channel onto the floodplain where the velocity magnitude was roughly 20-30% of the average channel velocity; (4) dense vegetation along the channel margins enhanced channel velocities but reduced

  2. Evolution of a meander in a constricted reach of a dryland alluvial channel: Little Colorado River, Arizona

    Science.gov (United States)

    Block, D.

    2013-12-01

    Lateral migration of river meander systems is complex, particularly in drylands where fluvial processes are discontinuous. Analysis of aerial photography and GPS tracking of cutbank erosion can further empirical knowledge of meander development. Moreover, discharge records link landscape response to hydroclimatic variability. In the semiarid Little Colorado River valley, extreme erosive episodes typically result from snowmelt flow, or lately, rain-on-snow events. The 90-km reach of the Little Colorado River (LCR), from Winslow to Leupp, Arizona, meanders within a 5-km-wide valley. Near Winslow, however, the LCR is disconnected from its floodplain by a 12-km-long levee. The levee restricts the floodplain to only 450 m wide in one location. In this severely constricted river stretch, a flood event in January 2008 relocated a meander bend. Bend development followed a common sequence of migration phases long noted in the literature, but at a very rapid pace. During the flood event one meander limb migrated ~200 m, following the general northwesterly flow direction of the river. Movement vectors of meander inflection points, apex, and apical line characterize changes in bend morphology. Before the 2008 flood event the apical line of the meander bend had azimuth 50°; after the 2008 flood event the apical line of the meander bend had azimuth 345°. Since that event, the meander bend has migrated an additional ~200 m through a combination of translation, extension, and rotation. The data provide information on geomorphic response to bimodal precipitation patterns in a human-perturbed channel reach.

  3. Meandered Monopoles for 700 MHz LTE Handsets and Improved MIMO Channel Capacity Performance

    Directory of Open Access Journals (Sweden)

    I. Dioum

    2011-12-01

    Full Text Available In this paper, we present the design and the measurement of MIMO meandered monopole antennas and the computation of their channel capacity performance. The initial proposed handset-system is composed of a meandered monopole operating in the LTE 700 MHz band, connected to a parasitic radiating element for the upper 2.5 GHz LTE band. Two antennas of the same kind are then closely positioned on the same 120x50 mm2 Printed Circuit Board (PCB. A neutralization line connects the two antennas to enhance their port-to-port isolation in the 700 MHz band. The computation of the channel capacity performance in this band is based on propagation simulations performed with the GRIMM model from the CREMANT. Two system-prototypes are evaluated: one with the neutralization line for enhanced port-to-port isolation and a second without the neutralization exhibiting poor antenna-to-antenna isolation. It is demonstrated that the neutralization technique helps in giving a minimum improvement of 12% of the capacity performance of the handset-system, and a maximum improvement 46%, in the chosen environment.

  4. A comparative study of longitudinal dispersion models in rigid vegetated compound meandering channels.

    Science.gov (United States)

    Farzadkhoo, Maryam; Keshavarzi, Alireza; Hamidifar, Hossein; Javan, Mahmood

    2018-03-26

    Releasing and mixing of pollutants in rivers can cause serious threats for downstream users. Longitudinal dispersion is an important factor in describing pollutant transport process in rivers. The focus of this study is on the effect of floodplain rigid vegetation characteristics including its arrangement, density and relative depth (the ratio of the flow depth in the main channel to that over floodplain) on flow and longitudinal dispersion coefficient in a meandering channel with compound cross section. Digital image processing technique was used to measure the tracer concentration. Sequential images were continuously captured at seven sections downstream of release point. PVC cylinders were installed over the floodplain to simulate rigid vegetation in tandem and random arrangements. Acoustic Doppler Velocimeter (Micro-ADV) was used to measure 3-D velocity components. The results showed that roughening the flood plain with stems increases the longitudinal flow velocity and Reynolds shear stress in the main channel, while these parameters decrease in the flood plain compared to non-vegetated cases. As a result, in the presence of rigid vegetation, the travel time decreases in the main channel up to 20% compared to non-vegetated conditions. As the relative flow depth increases, the dimensionless longitudinal dispersion coefficient, K/U ∗ H, decreases up to 74%. Also, the dimensionless longitudinal dispersion coefficient increases up to 38% with stem density in a specific relative flow depth of D r  = 0.11. Finally, a comparison has been made between laboratory data and some well-known previously reported models. Later, the most accurate equations are presented for predicting the longitudinal dispersion coefficient in rigid vegetated compound meandering channels. The results of the present study reveal that rigid vegetation over flood plain can be used as an alternative method in river rehabilitation projects for environmental management purposes. Copyright

  5. Channel and floodplain sediment dynamics in a reach of the tropical meandering Rio Beni (Bolivian Amazonia)

    OpenAIRE

    Gautier, E.; Brunstein, D.; Vauchel, Philippe; Jouanneau, J. M.; Roulet, Marc; Garcia, C.; Guyot, Jean-Loup; Castro, M.

    2010-01-01

    The study investigates interactions, water and sediment exchanges, between a rapidly migrating meander and its associated floodplain at fine temporal and spatial scales. The Beni River, an Amazonian free meandering river, makes the transition between Andean ranges and Amazonian lowlands. For the period 2002-2006, an assemblage of tools and methods (water and sediment discharges, topometric and bathymetric surveys, sedimentation rate estimations from unsupported Pb-210 and sediment trapping sy...

  6. Influence of Channel Morphology on Flow Hydraulics in a Compound Meander Bend of the Lower Brazos River, Texas

    Science.gov (United States)

    Hales, B. U.; Guneralp, I.; Filippi, A. M.

    2013-12-01

    At a meander-bend scale, process-form interactions between channel morphology and flow hydraulics generate unique features called geomorphic units, such as pools, sediment bars, and backwater regions. Geomorphic units play an important role as distinct habitats for aquatic species. In this study, we investigate channel morphology and flow structure of an incised meander bend on the lower Brazos River, Texas, to inform aquatic habitat assessment. The bend represents the characteristics of sand-bed and high-amplitude meandering rivers and contains a localized bank-protection structure along its cutbank. We examine: 1) the spatial characteristics of channel morphology (i.e., geomorphic units); 2) spatial characteristics of flow hydraulics in relation to geomorphic units at low- (Q1), medium- (Q2), and high- (Q3) discharge conditions; and 3) the influence of channel morphology on flow hydraulics within this meander bend. We utilize bathymetric and hydraulic surveys conducted using Acoustic Doppler Current Profiler (ADCP) and simultaneously collected bed-sediment samples. To characterize channel morphology, we use a digital terrain model (DTM) of the bend that we generate by fusing our bathymetric data and an airborne interferometric synthetic aperture radar (InSAR)-derived DTM. We examine flow hydraulics by performing quasi 3-D hydraulic modeling. Results show that channel morphology has a strong influence on the spatial distribution of hydraulic parameters, including water depth, flow velocities, Froude number, and helix strength. At Q1, the emergent mid-channel bar forces flow divergence/convergence and acts as a macro-roughness structure. High flow velocity concentrates in the deeper and narrower sub-channel along the cutbank side. At Q2, the location of the mid-channel bar shifts toward the point bar, forming a new chute sub-channel. Highest flow velocities are still concentrated in the permanent sub-channel along the cutbank, but shift downstream toward the exit

  7. Experiments in a high-amplitude Kinoshita meandering channel: 2. Implications of bend orientation on bed morphodynamics

    Science.gov (United States)

    Abad, Jorge D.; Garcia, Marcelo H.

    2009-02-01

    Experiments carried out under flat smooth bed condition in a periodic, asymmetric, Kinoshita meandering channel showed that bend skewness controls the three-dimensional mean flow (e.g., primary and secondary flow) and turbulence structure (e.g., location of shear layers and turbulent shear stresses). In this paper, similar hydraulic conditions are used to perform movable-bed experiments with uniform sediment size in order to study the effect of bend orientation on bed morphodynamics. Two main differences between the upstream- and downstream-skewed meander configurations are found: (1) for the case of bends oriented upstream valley, the bed forms are produced just upstream of the bend apex, whereas for the case of bends oriented downstream valley they are observed around the upstream inflection point, and (2) the downstream-skewed condition produces the deepest scour region, which is located downstream of the bend apex. A comparison with observations at two bends on the Wabash River, Illinois, shows some remarkable similarities with the bed morphology observed in the Kinoshita channel. Further analysis of the bed form celerity, bed load transport during evolution, and superimposition of migrating bed forms and their implications on bend migration are presented.

  8. Giant magnetoimpedance effect in sputtered single layered NiFe film and meander NiFe/Cu/NiFe film

    International Nuclear Information System (INIS)

    Chen, L.; Zhou, Y.; Lei, C.; Zhou, Z.M.; Ding, W.

    2010-01-01

    Giant magnetoimpedance (GMI) effect on NiFe thin film is very promising due to its application in developing the magnetic field sensors with highly sensitivity and low cost. In this paper, the single layered NiFe thin film and NiFe/Cu/NiFe thin film with a meander structure are prepared by the MEMS technology. The influences of sputtering parameters, film structure and conductor layer width on GMI effect in NiFe single layer and meander NiFe/Cu/NiFe film are investigated. Maximum of the GMI ratio in single layer and sandwich film is 5% and 64%, respectively. The results obtained are useful for developing the high-performance magnetic sensors based on NiFe thin film.

  9. Imaging and locating paleo-channels using geophysical data from meandering system of the Mun River, Khorat Plateau, Northeastern Thailand

    Science.gov (United States)

    Nimnate, P.; Thitimakorn, T.; Choowong, M.; Hisada, K.

    2017-12-01

    The Khorat Plateau from northeast Thailand, the upstream part of the Mun River flows through clastic sedimentary rocks. A massive amount of sand was transported. We aimed to understand the evolution of fluvial system and to discuss the advantages of two shallow geophysical methods for describing subsurface morphology of modern and paleo-channels. We applied Electrical Resistivity Tomography (ERT) and Ground Penetrating Radar (GPR) to characterize the lateral, vertical morphological and sedimentary structures of paleo-channels, floodplain and recent point bars. Both methods were interpreted together with on-sites boreholes to describe the physical properties of subsurface sediments. As a result, we concluded that four radar reflection patterns including reflection free, shingled, inclined and hummocky reflections were appropriated to apply as criteria to characterize lateral accretion, the meandering rivers with channel-filled sequence and floodplain were detected from ERT profiles. The changes in resistivity correspond well with differences in particle size and show relationship with ERT lithological classes. Clay, silt, sand, loam and bedrock were classified by the resistivity data. Geometry of paleo-channel embayment and lithological differences can be detected by ERT, whereas GPR provides detail subsurface facies for describing point bar sand deposit better than ERT.

  10. Preservation of meander channel and scour features under aggradational and non-aggradational conditions

    NARCIS (Netherlands)

    Lageweg, W.I. van de; Schuurman, F.; Shimizu, Y.; Cohen, K.M.; Dijk, W.M. van; Kleinhans, M.G.

    2013-01-01

    The internal architecture of channel belts commonlyconsists of channel-form bounding surfaces due to channelmigration and scouring (e.g. Miall, 1985). These boundingsurfaces are essential to our reconstructions of palaeochannel dimensions. It is therefore crucial tounderstand the suite of processes

  11. Quantification of shear stress in a meandering native topographic channel using a physical hydraulic model

    Science.gov (United States)

    Michael E. Ursic; Christopher I. Thornton; Amanda L. Cox; Steven R. Abt

    2012-01-01

    Fluvial systems respond to changes in boundary conditions in order to sustain the flow and sediment supplied to the system. Local channel responses are typically difficult to predict due to possible affects from upstream, downstream, or local boundary conditions that cause changes in channel or planform geometry. Changes to the system can threaten riverside...

  12. Hydraulic Losses in River Meanders

    National Research Council Canada - National Science Library

    Brown, Gary L; Copeland, Ronald R; Fischenich, Craig

    2007-01-01

    .... These coefficients are determined empirically. Although much research has been expended developing relations for resistance due to grain size, bed form, and vegetation, relatively little research has focused on the influence of channel meanders...

  13. Quantification of shear stress in a meandering native topographic channel using a physical hydraulic model

    Science.gov (United States)

    Michael E. Ursic

    2011-01-01

    Current guidelines for predicting increases in shear stress in open-channel bends were developed from investigations that were primarily prismatic in cross section. This study provides possible increases in shear stress relative to approach flow conditions resulting from planimetric and topographic geometric features. Boundary shear stress estimates were determined by...

  14. The meandering Indus, channels: Study in a small area by the multibeam swath bathymetry system - Hydrosweep

    Digital Repository Service at National Institute of Oceanography (India)

    Kodagali, V.N.; Jauhari, P.

    The discharge of sediments by the river Indus has accumulated into a 2500 m thick pile, forming one of the largest deep sea fans in the world. Though there are many reports on channels in different regions of tha fan, we report for the first time...

  15. Single top t-channel

    CERN Document Server

    Faltermann, Nils

    2017-01-01

    The production of single top quarks allows to study the interplay of top quark physics and the electroweak sector of the standard model. Deviations from predictions can be a hint for physics beyond the standard model. The t-channel is the dominant production mode for single top quarks at the LHC. This talk presents the latest measurements from the ATLAS and CMS collaborations.

  16. Einstein's meanders

    Science.gov (United States)

    Lomnitz, C.

    2007-05-01

    What does Einstein have to do with subduction? Good question. Peaceful Lake Budi, lying at the heart of an Indian reservation in the Deep South of Chile, had subsided by two meters in the 1960 mega-thrust earthquake. This unique South American salt lake was hiding an awful secret: it was actually an oxbow, not a lake. But Einstein had realized in 1926 that meanders are natural freaks. Rivers will not flow uphill, yet - he claimed - they don't flow down the path of steepest descent either. This anomaly was put at the doorstep of a weak Coriolis Force. Thus Einstein problematized the dilemma of the earth sciences. How can a non-force produce margin-parallel compression in a convergent margin where extension is expected? In fact, where does the energy for meander formation come from? Good question . . . Even Wikipedia knows that Coriolis is not a “force” but an “effect”. So is the obliquity of plate convergence in subduction. Where did Einstein err, and where was he a pioneer? Coastal ablation plus alternating subsidence and emergence in giant earthquakes may yield an answer. Einstein, A. (1926). Die Ursache der Maeanderbildung der Flusslaeufe und das sogenannte Baersche Gesetz, Naturwissenschaften, 14, fascicle II.

  17. Dynamic wake meandering modeling

    DEFF Research Database (Denmark)

    Larsen, Gunner Chr.; Madsen Aagaard, Helge; Bingöl, Ferhat

    We present a consistent, physically based theory for the wake meandering phenomenon, which we consider of crucial importance for the overall description of wind turbine loadings in wind farms. In its present version the model is confined to single wake situations. The model philosophy does, however......, are an integrated part the model complex. For design applications, the computational efficiency of wake deficit prediction is a key issue. Two computationally low cost models are developed for this purpose. The character of the added wake turbulence, generated by the up-stream turbine in the form of shed......, concerning both flow characteristics and turbine load characteristics. Contrary to previous attempts to model wake loading, the dynamic wake meandering approach opens for a unifying description in the sense that turbine power– and load aspects can be treated simultaneously. This capability is a direct...

  18. Dendrogeochronologic and Anatomic Analysis of Excavated Plains Cottonwoods Determine Overbank Sedimentation Rates and Historical Channel Positions Along the Interior of a Migrating Meander Bend, Powder River, Montana

    Science.gov (United States)

    Metzger, T. L.; Pizzuto, J. E.; Schook, D. M.; Hasse, T. R.; Affinito, R. A.

    2017-12-01

    Dendrochronological dating of buried trees precisely determines the germination year and identifies the stratigraphic context of germination for the trees. This recently developed application of dendrochronology provides accurate time-averaged sedimentation rates of overbank deposition along floodplains and can be used to identify burial events. Previous studies have demonstrated that tamarisk (Tamarix ramosissima) and sandbar willow (Salix exigua) develop anatomical changes within the tree rings (increased vessel size and decreased ring widths) on burial, but observations of plains cottonwood (Populus deltoides ssp. monilifera) are lacking. In September 2016 and June 2017, five buried plains cottonwoods were excavated along a single transect of the interior of a meander bend of the Powder River, Montana. Sediment samples were obtained near each tree for 210Pb and 137Cs dating, which will allow for comparison between dendrochronological and isotopic dating methods. The plains cottonwood samples collected exhibit anatomical changes associated with burial events that are observed in other species. All trees germinated at the boundary between thinly bedded fine sand and mud and coarse sand underlain by sand and gravel, indicating plains cottonwoods germinate on top of point bars prior to overbank deposition. The precise germination age and depth provide elevations and minimum age constraints for the point bar deposits and maximum ages for the overlying sediment, helping constrain past channel positions and overbank deposition rates. Germination years of the excavated trees, estimated from cores taken 1.5 m above ground level, range from 2014 to 1862. Accurate establishment years determined by cross-dating the buried section of the tree can add an additional 10 years to the cored age. The sedimentation rate and accumulation thickness varied with tree age. The germination year, total sediment accumulation, and average sedimentation rate at the five sampled trees is

  19. Modification of single Na+ channels by batrachotoxin.

    OpenAIRE

    Quandt, F N; Narahashi, T

    1982-01-01

    The modifications in the properties of voltage-gated Na+ channels caused by batrachotoxin were studied by using the patch clamp method for measuring single channel currents from excised membranes of N1E-115 neuroblastoma cells. The toxin-modified open state of the Na+ channel has a decreased conductance in comparison to that of normal Na+ channels. The lifetime of the modified open state is drastically prolonged, and channels now continue to open during a maintained depolarization so that the...

  20. On the migration rate of tidal meanders

    Science.gov (United States)

    D'Alpaos, A.; Finotello, A.; Ghinassi, M.; Lanzoni, S.; Marani, M.; Rinaldo, A.

    2016-12-01

    Sinuous channels shaped by periodically reversing tidal flows are a ubiquitous feature of tidal landscapes. Despite their fundamental role on the morphology and sedimentary patterns of these landscapes, tidal meanders have received less attention than their fluvial counterparts, particularly as far as migration processes are concerned. We have analyzed the migration of about 300 meander bends in the Northern Venice Lagoon (Italy), from 1968 to nowadays, through observations and modeling interpretation. Similarities with fluvial meanders occur, although important difference also emerge. Meanders cutting through salt-marshes in the Venice Lagoon follow the relationship between Cartesian length and channel width, typical of meanders developed within different settings. We find a mean migration rate of about 0.20 m/year. However, the potential migration rate can reach values of about 0.20 channel widths per year thus suggesting similarities with fluvial meanders. In addition, tidal channel migration dynamics displays features which qualitatively agree with theories developed for the fluvial setting. We deem our results are valuable for the understanding of the morphological evolution and architecture of tidal landscapes, with implications for restoration strategies, also in the face of changes in environmental conditions.

  1. Single-channel kinetics of BK (Slo1 channels

    Directory of Open Access Journals (Sweden)

    Yanyan eGeng

    2015-01-01

    Full Text Available Single-channel kinetics has proven a powerful tool to reveal information about the gating mechanisms that control the opening and closing of ion channels. This introductory review focuses on the gating of large conductance Ca2+- and voltage-activated K+ (BK or Slo1 channels at the single-channel level. It starts with single-channel current records and progresses to presentation and analysis of single-channel data and the development of gating mechanisms in terms of discrete state Markov (DSM models. The DSM models are formulated in terms of the tetrameric modular structure of BK channels, consisting of a central transmembrane pore-gate domain (PGD attached to four surrounding transmembrane voltage sensing domains (VSD and a large intracellular cytosolic domain (CTD, also referred to as the gating ring. The modular structure and data analysis shows that the Ca2+ and voltage dependent gating considered separately can each be approximated by 10-state two-tiered models with 5 closed states on the upper tier and 5 open states on the lower tier. The modular structure and joint Ca2+ and voltage dependent gating are consistent with a 50 state two-tiered model with 25 closed states on the upper tier and 25 open states on the lower tier. Adding an additional tier of brief closed (flicker states to the 10-state or 50-state models improved the description of the gating. For fixed experimental conditions a channel would gate in only a subset of the potential number of states. The detected number of states and the correlations between adjacent interval durations are consistent with the tiered models. The examined models can account for the single-channel kinetics and the bursting behavior of gating. Ca2+ and voltage activate BK channels by predominantly increasing the effective opening rate of the channel with a smaller decrease in the effective closing rate. Ca2+ and depolarization thus activate by mainly destabilizing the closed states.

  2. Decadal changes in channel morphology of a freely meandering river—Powder River, Montana, 1975–2016

    Science.gov (United States)

    Moody, John A.; Meade, Robert H.

    2018-03-19

    Few studies exist on the long-term geomorphic effects of floods. However, the U.S. Geological Survey (USGS) was able to begin such a study after a 50-year recurrence interval flood in 1978 because 20 channel cross sections along a 100-kilometer reach of river were established in 1975 and 1977 as part of a study for a proposed dam on Powder River in southeastern Montana. These cross-section measurements (data for each channel cross section are available at the USGS ScienceBase website) have been repeated about 30 times during four decades (1975–2016) and provide a unique dataset for understanding long-term changes in channel morphology caused by an extreme flood and a spectrum of annual floods.Changes in channel morphology of a 100-kilometer reach of Powder River are documented in a series of narratives for each channel cross section that include a time series of photographs as a record of these changes. The primary change during the first decade (1975–85) was the rapid vertical growth of a new inset flood plain within the flood-widened channel. Changes during the second decade (1985–95) were characterized by slower growth of the flood plain, and the effects of ice-jam floods typical of a northward-flowing river. Changes during the third decade (1995–2005) showed little vertical growth of the inset flood plain, which had reached a height that limited overbank deposition. And changes during the final decade (2005–16) covered in this report showed that, because the new inset flood plain had reached a limiting height, the effects of the large annual flood of 2008 (largest flood since 1978) were relatively small compared to smaller floods in previous decades. Throughout these four decades, the riparian vegetation, which interacts with the river, has undergone a gradual but substantial change that may have lasting effects on the channel morphology.

  3. Modification of single Na+ channels by batrachotoxin.

    Science.gov (United States)

    Quandt, F N; Narahashi, T

    1982-11-01

    The modifications in the properties of voltage-gated Na+ channels caused by batrachotoxin were studied by using the patch clamp method for measuring single channel currents from excised membranes of N1E-115 neuroblastoma cells. The toxin-modified open state of the Na+ channel has a decreased conductance in comparison to that of normal Na+ channels. The lifetime of the modified open state is drastically prolonged, and channels now continue to open during a maintained depolarization so that the probability of a channel being open becomes constant. Modified and normal open states of Na+ channels coexist in batrachotoxin-exposed membrane patches. Unlike the normal condition, Na+ channels exposed to batrachotoxin open spontaneously at large negative potentials. These spontaneous openings apparently cause the toxin-induced increase in Na+ permeability which, in turn, causes membrane depolarization.

  4. An integrated approach to investigate the reach-averaged bend scale dynamics of large meandering rivers

    Science.gov (United States)

    Monegaglia, Federico; Henshaw, Alex; Zolezzi, Guido; Tubino, Marco

    2016-04-01

    Planform development of evolving meander bends is a beautiful and complex dynamic phenomenon, controlled by the interplay among hydrodynamics, sediments and floodplain characteristics. In the past decades, morphodynamic models of river meandering have provided a thorough understanding of the unit physical processes interacting at the reach scale during meander planform evolution. On the other hand, recent years have seen advances in satellite geosciences able to provide data with increasing resolution and earth coverage, which are becoming an important tool for studying and managing river systems. Analysis of the planform development of meandering rivers through Landsat satellite imagery have been provided in very recent works. Methodologies for the objective and automatic extraction of key river development metrics from multi-temporal satellite images have been proposed though often limited to the extraction of channel centerlines, and not always able to yield quantitative data on channel width, migration rates and bed morphology. Overcoming such gap would make a major step forward to integrate morphodynamic theories, models and real-world data for an increased understanding of meandering river dynamics. In order to fulfill such gaps, a novel automatic procedure for extracting and analyzing the topography and planform dynamics of meandering rivers through time from satellite images is implemented. A robust algorithm able to compute channel centerline in complex contexts such as the presence of channel bifurcations and anabranching structures is used. As a case study, the procedure is applied to the Landsat database for a reach of the well-known case of Rio Beni, a large, suspended load dominated, tropical meandering river flowing through the Bolivian Amazon Basin. The reach-averaged evolution of single bends along Rio Beni over a 30 years period is analyzed, in terms of bend amplification rates computed according to the local centerline migration rate. A

  5. Similarities and differences between a large meandering river and an anabranching river: the Ucayali and Amazon River cases

    Science.gov (United States)

    Abad, J. D.; Paredes, J. R.; Montoro, H.

    2010-12-01

    The Ucayali is one of the largest freely meandering rivers in the world and its planform migration produces complex meander shapes dominated by not only fluvial erosion but mainly geotechnical processes since changes on water stage are appreciable compared to medium- and small-meander rivers. The Amazon is one of the largest anabranching rivers in the world and it is formed by the confluence of the anabranching Marañon River together with the meandering Ucayali River. The seasonal increase and decrease in water and sediment discharges from the Amazonian lowland rivers produce changes in the river’s planform configuration, river flooding, and streambank erosion affecting nearby towns and navigation and shoaling issues. Even though, extensive work has been dedicated to understand both river systems, there is still no absolute understanding of their physically-based formation processes and dynamics, especially at large scales as these lowland Amazonian rivers. The Ucayali Meandering River migrates at greater rates than the Amazon Anabranching River mainly due to their single channel condition; however localized secondary channels of the latter could behave as meandering channels dominating and modifying the planform dynamics of the entire anabranching system. Insights on how a large meandering river (Ucayali) is similar and at the same time different from an anabranching river (Amazon) will be described herein. A team composed of the Earth Processes & Environmental Flows Group (EPEF) at the University of Pittsburgh and the Directorate of Hydrology and Navigation (DHN) from the Peruvian Navy is working towards gathering information and field measurements concerning the dynamics of the Amazonian rivers. Therefore, based on three-dimensional velocity and bed morphodynamic measurements (performed in both river systems using acoustic profilers and echo sounders respectively) combined with mathematical hydrodynamic models, some insights on the flow structure, bed

  6. Bilateral meandering pulmonary veins

    Energy Technology Data Exchange (ETDEWEB)

    Thupili, Chakradhar R.; Udayasankar, Unni [Pediatric Imaging, Imaging Institute Cleveland Clinic, Cleveland, OH (United States); Renapurkar, Rahul [Imaging Institute Cleveland Clinic, Thoracic Imaging, L10, Cleveland, OH (United States)

    2015-06-15

    Meandering pulmonary veins is a rare clinical entity that can be mistaken for more complex congenital syndromes such as hypogenetic lung syndrome. We report imaging findings in a rare incidentally detected case of bilateral meandering pulmonary veins. We briefly discuss the role of imaging in diagnosing this condition, with particular emphasis on contrast-enhanced CT. (orig.)

  7. Interactions between Point Bar Growth and Bank Erosion on a Low Sinuosity Meander Bend in an Ephemeral Channel: Insights from Repeat Topographic Surveys and Numerical Modeling

    Science.gov (United States)

    Ursic, M.; Langendoen, E. J.

    2017-12-01

    Interactions between point bar growth, bank migration, and hydraulics on meandering rivers are complicated and not well understood. For ephemeral streams, rapid fluctuations in flow further complicate studying and understanding these interactions. This study seeks to answer the following `cause-and-effect' question: Does point bar morphologic adjustment determine where bank erosion occurs (for example, through topographic steering of the flow), or does local bank retreat determine where accretion/erosion occurs on the point bar, or do bank erosion and point bar morphologic adjustment co-evolve? Further, is there a response time between the `cause-and-effect' processes and what variables determine its magnitude and duration? In an effort to answer these questions for an ephemeral stream, a dataset of forty-eight repeat topographic surveys over a ten-year period (1996-2006) of a low sinuosity bend within the Goodwin Creek Experimental Watershed, located near Batesville, MS, were utilized in conjunction with continuous discharge measurements to correlate flow variability and erosional and depositional zones, spatially and temporally. Hydraulically, the bend is located immediately downstream of a confluence with a major tributary. Supercritical flumes on both the primary and tributary channels just upstream of the confluence provide continuous measured discharges to the bend over the survey period. In addition, water surface elevations were continuously measured at the upstream and downstream ends of the bend. No spatial correlation trends could be discerned between reach-scale bank retreat, point bar morphologic adjustment, and flow discharge. Because detailed flow patterns were not available, the two-dimensional computer model Telemac2D was used to provide these details. The model was calibrated and validated for a set of runoff events for which more detailed flow data were available. Telemac2D simulations were created for each topographic survey period. Flows

  8. Meander reconnection method determines restoration success for macroinvertebrate communities in a German lowland river

    DEFF Research Database (Denmark)

    Lorenz, Stefan; Leszinski, Marc; Graeber, Daniel

    2016-01-01

    Re-meandering of degraded rivers is a frequently implemented measure in river restoration. A simple solution is reconnection of old meanders; however, its success likely depends on the reconnection method. We conducted a field study to analyze the benefits of a fully reconnected (fully opened...... meander, blocked main channel) and a partially reconnected meander (opened downstream, pipe bypass from main channel upstream, still open main channel) for macroinvertebrate communities in a German lowland river. Immediately upon reconnection of the two meanders, habitat diversity and macroinvertebrates...

  9. Field migration rates of tidal meanders recapitulate fluvial morphodynamics.

    Science.gov (United States)

    Finotello, Alvise; Lanzoni, Stefano; Ghinassi, Massimiliano; Marani, Marco; Rinaldo, Andrea; D'Alpaos, Andrea

    2018-02-13

    The majority of tidal channels display marked meandering features. Despite their importance in oil-reservoir formation and tidal landscape morphology, questions remain on whether tidal-meander dynamics could be understood in terms of fluvial processes and theory. Key differences suggest otherwise, like the periodic reversal of landscape-forming tidal flows and the widely accepted empirical notion that tidal meanders are stable landscape features, in stark contrast with their migrating fluvial counterparts. On the contrary, here we show that, once properly normalized, observed migration rates of tidal and fluvial meanders are remarkably similar. Key to normalization is the role of tidal channel width that responds to the strong spatial gradients of landscape-forming flow rates and tidal prisms. We find that migration dynamics of tidal meanders agree with nonlinear theories for river meander evolution. Our results challenge the conventional view of tidal channels as stable landscape features and suggest that meandering tidal channels recapitulate many fluvial counterparts owing to large gradients of tidal prisms across meander wavelengths. Copyright © 2018 the Author(s). Published by PNAS.

  10. Field migration rates of tidal meanders recapitulate fluvial morphodynamics

    Science.gov (United States)

    Finotello, Alvise; Lanzoni, Stefano; Ghinassi, Massimiliano; Marani, Marco; Rinaldo, Andrea; D'Alpaos, Andrea

    2018-02-01

    The majority of tidal channels display marked meandering features. Despite their importance in oil-reservoir formation and tidal landscape morphology, questions remain on whether tidal-meander dynamics could be understood in terms of fluvial processes and theory. Key differences suggest otherwise, like the periodic reversal of landscape-forming tidal flows and the widely accepted empirical notion that tidal meanders are stable landscape features, in stark contrast with their migrating fluvial counterparts. On the contrary, here we show that, once properly normalized, observed migration rates of tidal and fluvial meanders are remarkably similar. Key to normalization is the role of tidal channel width that responds to the strong spatial gradients of landscape-forming flow rates and tidal prisms. We find that migration dynamics of tidal meanders agree with nonlinear theories for river meander evolution. Our results challenge the conventional view of tidal channels as stable landscape features and suggest that meandering tidal channels recapitulate many fluvial counterparts owing to large gradients of tidal prisms across meander wavelengths.

  11. Georectification of historical aerial photos to track meander change in Wood River, Klamath County, Oregon

    Science.gov (United States)

    Nash, C.; Hughes, M. L.

    2010-12-01

    , triggering serial extension of proximal meanders. In the lower reaches, where valley slope is lower, the meander belt virtually vanishes and the river flows through levees perched over partially drained lake-fringe wetlands. Sinuosity is generally low in these reaches and, in contrast to the upper reaches, increased in several areas. This increase in sinuosity can be partially attributed to a restoration project carried out by the Bureau of Land Management that re-meandering the lower 2 miles of the river channel in 2002. The single largest channel change occurred in the transition between the upper and lower reaches, where a series of meanders where artificially straightened. Fundamental differences in the hydrogeomorphology of the Wood River in the upper (more active), middle (straightened), and lower (narrower, less active, leveed) reaches imply different opportunities and constraints for ecological river restoration. Whereas restoration in the upper river and middle reaches could emphasize promoting natural processes and patterns of river meandering, re-establishing the geohydrologic connection between the channel and adjacent wetland systems appears to be the most urgent need in the lower river.

  12. Meandering rivers: Interpreting dynamics from planform geometry and the secret lives of migrating meanders

    Science.gov (United States)

    Schwenk, Jonathan

    Meandering rivers are dynamic agents of geomorphic change that rework landscapes through migration while maintaining beautiful looping planforms. This work investigates the relationships between the alluring planform geometries of meandering rivers, the dynamics of individual meander bend migration, and the dynamic processes driving meander evolution. A simple yet physically-based model of long-time meander migration is employed to understand the dynamic trajectories of individual meander bends and establish relationships between historic dynamics and cutoff bend geometry. At the reach scale, concepts from nonlinear dynamic theory are applied to river centerlines to determine if the dynamic nonlinearities driving meander evolution are preserved in the reachwide planform structure. Understanding how rivers move across their floodplains requires snapshots of planforms over long time periods from aerial photography or historic maps and surveys which are often taken at irregular and long intervals. Migration occurring between snapshots has thus largely remained a mystery. More recently, worldwide satellite imagery collected at least every 18 days by the NASA Landsat family of satellites offers the potential to reveal the secret lives of migrating, meandering rivers. This research mines the vault of Landsat imagery to resolve over 30 years of planform migration along more than 1,300 km of one of the Earth's most active meandering rivers: the Ucayali River in Peru. Analysis of the resulting annual binary channel masks suggests that migration rates are controlled by processes acting across bend-to-reach scales. An exciting new geomorphic discovery emerges from the analysis revealing the role of cutoffs as drivers of nonlocal morphodynamic change.

  13. Low Complexity Bayesian Single Channel Source Separation

    DEFF Research Database (Denmark)

    Beierholm, Thomas; Pedersen, Brian Dam; Winther, Ole

    2004-01-01

    We propose a simple Bayesian model for performing single channel speech separation using factorized source priors in a sliding window linearly transformed domain. Using a one dimensional mixture of Gaussians to model each band source leads to fast tractable inference for the source signals. Simul...

  14. Single-thread channels resulting from a localization process driven by vegetation

    Science.gov (United States)

    Narteau, C.; Tal, M.

    2009-12-01

    The unpredictable manner in which braided rivers evolve is in stark contrast to the orderly migration pattern of meandering rivers driven by erosion along outer bends and deposition along inner banks. Braided channels are the default pattern that develops when an unbounded water flow interacts with noncohesive sediment. A series of laboratory experiments demonstrated that plants alone are able to achieve the two key mechanisms to developing meandering: slowing the rate of widening and discouraging channel cutoffs. Plants initially colonized braid-bars that were emergent during low flow. By adding cohesion to the sediment and increasing roughness, vegetation deterred the flow from reoccupying areas which were colonized. By decreasing erosion rates, plants made it possible for deposition along the inner bank to match the rate of erosion along the outer bank. This enabled the channel to develop sinuosity and migrate laterally while suppressing channel splitting and the creation of new channel width. Areas with established vegetation provided stable conditions which promoted new seedling establishment and expansion of the vegetated area. A generic mechanism of width production in the braided state is the opportunistic creation of new channels. As existing flow paths become slightly less favorable, for example by bar deposition or an increase in sinuosity, new ones are readily created in areas that are not currently occupied by flow. By making it more difficult for flow to occupy vegetated areas, plants in effect decouple the transition between wet and dry areas, making it harder for areas that are dry (vegetated) to turn wet (reoccupied by flow) and less likely for areas that are wet to become dry. The net effect is localization of the flow into a single-thread channel with transitions between wet and dry occurring predominantly along the channel margin and driving lateral migration while a single-thread channel remains intact. We are using a 1D cellular automata model

  15. River meander modeling and confronting uncertainty.

    Energy Technology Data Exchange (ETDEWEB)

    Posner, Ari J. (University of Arizona Tucson, AZ)

    2011-05-01

    This study examines the meandering phenomenon as it occurs in media throughout terrestrial, glacial, atmospheric, and aquatic environments. Analysis of the minimum energy principle, along with theories of Coriolis forces (and random walks to explain the meandering phenomenon) found that these theories apply at different temporal and spatial scales. Coriolis forces might induce topological changes resulting in meandering planforms. The minimum energy principle might explain how these forces combine to limit the sinuosity to depth and width ratios that are common throughout various media. The study then compares the first order analytical solutions for flow field by Ikeda, et al. (1981) and Johannesson and Parker (1989b). Ikeda's et al. linear bank erosion model was implemented to predict the rate of bank erosion in which the bank erosion coefficient is treated as a stochastic variable that varies with physical properties of the bank (e.g., cohesiveness, stratigraphy, or vegetation density). The developed model was used to predict the evolution of meandering planforms. Then, the modeling results were analyzed and compared to the observed data. Since the migration of a meandering channel consists of downstream translation, lateral expansion, and downstream or upstream rotations several measures are formulated in order to determine which of the resulting planforms is closest to the experimental measured one. Results from the deterministic model highly depend on the calibrated erosion coefficient. Since field measurements are always limited, the stochastic model yielded more realistic predictions of meandering planform evolutions. Due to the random nature of bank erosion coefficient, the meandering planform evolution is a stochastic process that can only be accurately predicted by a stochastic model.

  16. Sinusoidal masks for single channel speech separation

    DEFF Research Database (Denmark)

    Mowlaee, Pejman; Christensen, Mads Græsbøll; Jensen, Søren Holdt

    2010-01-01

    In this paper we present a new approach for binary and soft masks used in single-channel speech separation. We present a novel approach called the sinusoidal mask (binary mask and Wiener filter) in a sinusoidal space. Theoretical analysis is presented for the proposed method, and we show that the......In this paper we present a new approach for binary and soft masks used in single-channel speech separation. We present a novel approach called the sinusoidal mask (binary mask and Wiener filter) in a sinusoidal space. Theoretical analysis is presented for the proposed method, and we show...... that the proposed method is able to minimize the target speech distortion while suppressing the crosstalk to a predetermined threshold. It is observed that compared to the STFTbased masks, the proposed sinusoidal masks improve the separation performance in terms of objective measures (SSNR and PESQ) and are mostly...

  17. Visualization Techniques for Single Channel DPF Systems

    Energy Technology Data Exchange (ETDEWEB)

    Dillon, Heather E.; Maupin, Gary D.; Carlson, Shelley J.; Saenz, Natalio T.; Gallant, Thomas R.

    2007-04-01

    New techniques have been developed to visualize soot deposition in both traditional and new diesel particulate filter (DPF) substrate materials using a modified cyanoacrylate fuming technique. Loading experiments have been conducted on a variety of single channel DPF substrates to develop a deeper understanding of soot penetration, soot deposition characteristics, and to confirm modeling results. Early results indicate that stabilizing the soot layer using a vapor adhesive may allow analysis of the layer with new methods.

  18. Calcium signals driven by single channel noise.

    Directory of Open Access Journals (Sweden)

    Alexander Skupin

    Full Text Available Usually, the occurrence of random cell behavior is appointed to small copy numbers of molecules involved in the stochastic process. Recently, we demonstrated for a variety of cell types that intracellular Ca2+ oscillations are sequences of random spikes despite the involvement of many molecules in spike generation. This randomness arises from the stochastic state transitions of individual Ca2+ release channels and does not average out due to the existence of steep concentration gradients. The system is hierarchical due to the structural levels channel--channel cluster--cell and a corresponding strength of coupling. Concentration gradients introduce microdomains which couple channels of a cluster strongly. But they couple clusters only weakly; too weak to establish deterministic behavior on cell level. Here, we present a multi-scale modelling concept for stochastic hierarchical systems. It simulates active molecules individually as Markov chains and their coupling by deterministic diffusion. Thus, we are able to follow the consequences of random single molecule state changes up to the signal on cell level. To demonstrate the potential of the method, we simulate a variety of experiments. Comparisons of simulated and experimental data of spontaneous oscillations in astrocytes emphasize the role of spatial concentration gradients in Ca2+ signalling. Analysis of extensive simulations indicates that frequency encoding described by the relation between average and standard deviation of interspike intervals is surprisingly robust. This robustness is a property of the random spiking mechanism and not a result of control.

  19. Calcium signals driven by single channel noise.

    Science.gov (United States)

    Skupin, Alexander; Kettenmann, Helmut; Falcke, Martin

    2010-08-05

    Usually, the occurrence of random cell behavior is appointed to small copy numbers of molecules involved in the stochastic process. Recently, we demonstrated for a variety of cell types that intracellular Ca2+ oscillations are sequences of random spikes despite the involvement of many molecules in spike generation. This randomness arises from the stochastic state transitions of individual Ca2+ release channels and does not average out due to the existence of steep concentration gradients. The system is hierarchical due to the structural levels channel--channel cluster--cell and a corresponding strength of coupling. Concentration gradients introduce microdomains which couple channels of a cluster strongly. But they couple clusters only weakly; too weak to establish deterministic behavior on cell level. Here, we present a multi-scale modelling concept for stochastic hierarchical systems. It simulates active molecules individually as Markov chains and their coupling by deterministic diffusion. Thus, we are able to follow the consequences of random single molecule state changes up to the signal on cell level. To demonstrate the potential of the method, we simulate a variety of experiments. Comparisons of simulated and experimental data of spontaneous oscillations in astrocytes emphasize the role of spatial concentration gradients in Ca2+ signalling. Analysis of extensive simulations indicates that frequency encoding described by the relation between average and standard deviation of interspike intervals is surprisingly robust. This robustness is a property of the random spiking mechanism and not a result of control.

  20. River meander modeling of the Wabash River near the Interstate 64 Bridge near Grayville, Illinois

    Science.gov (United States)

    Lant, Jeremiah G.; Boldt, Justin A.

    2018-01-16

    Natural river channels continually evolve and change shape over time. As a result, channel evolution or migration can cause problems for bridge structures that are fixed in the flood plain. A once-stable bridge structure that was uninfluenced by a river’s shape could be encroached upon by a migrating river channel. The potential effect of the actively meandering Wabash River on the Interstate 64 Bridge at the border with Indiana near Grayville, Illinois, was studied using a river migration model called RVR Meander. RVR Meander is a toolbox that can be used to model river channel meander migration with physically based bank erosion methods. This study assesses the Wabash River meandering processes through predictive modeling of natural meandering over the next 100 years, climate change effects through increased river flows, and bank protection measures near the Interstate 64 Bridge.

  1. Single Wake Meandering, Advection and Expansion - An analysis using an adapted Pulsed Lidar and CFD LES-ACL simulations

    DEFF Research Database (Denmark)

    Machefaux, Ewan; Larsen, Gunner Chr.; Troldborg, Niels

    2013-01-01

    In this paper, single wake characteristics have been studied both experimentally and numerically. Firstly, the wake is studied experimentally using full-scale measurements from an adapted focused pulsed lidar system, which potentially gives more insight into the wake dynamics as compared to class...... using the EllipSys3D flow solver using Large Eddy Simulation (LES) and Actuator Line Technique (ACL) to model the rotor. Discrepancies due to the uncertainties on the wake advection velocity are observed and discussed....

  2. Single Wake Meandering, Advection and Expansion - An analysis using an adapted Pulsed Lidar and CFD LES-ACL simulations

    DEFF Research Database (Denmark)

    In this paper, single wake characteristics have been studied both experimentally and numerically. Firstly, the wake is studied experimentally using full-scale measurements from an adapted focused pulsed lidar system, which potentially gives more insight into the wake dynamics as compared to class...... using the EllipSys3D flow solver using Large Eddy Simulation (LES) and Actuator Line Technique (ACL) to model the rotor. Discrepancies due to the uncertainties on the wake advection velocity are observed and discussed....

  3. Ventricular beat detection in single channel electrocardiograms.

    Science.gov (United States)

    Dotsinsky, Ivan A; Stoyanov, Todor V

    2004-01-29

    Detection of QRS complexes and other types of ventricular beats is a basic component of ECG analysis. Many algorithms have been proposed and used because of the waves' shape diversity. Detection in a single channel ECG is important for several applications, such as in defibrillators and specialized monitors. The developed heuristic algorithm for ventricular beat detection includes two main criteria. The first of them is based on steep edges and sharp peaks evaluation and classifies normal QRS complexes in real time. The second criterion identifies ectopic beats by occurrence of biphasic wave. It is modified to work with a delay of one RR interval in case of long RR intervals. Other algorithm branches classify already detected QRS complexes as ectopic beats if a set of wave parameters is encountered or the ratio of latest two RR intervals RRi-1/RRi is less than 1:2.5. The algorithm was tested with the AHA and MIT-BIH databases. A sensitivity of 99.04% and a specificity of 99.62% were obtained in detection of 542014 beats. The algorithm copes successfully with different complicated cases of single channel ventricular beat detection. It is aimed to simulate to some extent the experience of the cardiologist, rather than to rely on mathematical approaches adopted from the theory of signal analysis. The algorithm is open to improvement, especially in the part concerning the discrimination between normal QRS complexes and ectopic beats.

  4. Achieving single channel, full duplex wireless communication

    KAUST Repository

    Choi, Jung Il

    2010-01-01

    This paper discusses the design of a single channel full-duplex wireless transceiver. The design uses a combination of RF and baseband techniques to achieve full-duplexing with minimal effect on link reliability. Experiments on real nodes show the full-duplex prototype achieves median performance that is within 8% of an ideal full-duplexing system. This paper presents Antenna Cancellation, a novel technique for self-interference cancellation. In conjunction with existing RF interference cancellation and digital baseband interference cancellation, antenna cancellation achieves the amount of self-interference cancellation required for full-duplex operation. The paper also discusses potential MAC and network gains with full-duplexing. It suggests ways in which a full-duplex system can solve some important problems with existing wireless systems including hidden terminals, loss of throughput due to congestion, and large end-to-end delays. Copyright 2010 ACM.

  5. Automated parallel recordings of topologically identified single ion channels.

    Science.gov (United States)

    Kawano, Ryuji; Tsuji, Yutaro; Sato, Koji; Osaki, Toshihisa; Kamiya, Koki; Hirano, Minako; Ide, Toru; Miki, Norihisa; Takeuchi, Shoji

    2013-01-01

    Although ion channels are attractive targets for drug discovery, the systematic screening of ion channel-targeted drugs remains challenging. To facilitate automated single ion-channel recordings for the analysis of drug interactions with the intra- and extracellular domain, we have developed a parallel recording methodology using artificial cell membranes. The use of stable lipid bilayer formation in droplet chamber arrays facilitated automated, parallel, single-channel recording from reconstituted native and mutated ion channels. Using this system, several types of ion channels, including mutated forms, were characterised by determining the protein orientation. In addition, we provide evidence that both intra- and extracellular amyloid-beta fragments directly inhibit the channel open probability of the hBK channel. This automated methodology provides a high-throughput drug screening system for the targeting of ion channels and a data-intensive analysis technique for studying ion channel gating mechanisms.

  6. Nonlinear simulation of meander evolution

    NARCIS (Netherlands)

    Chen, D.; Zhang, Y.; Ottevanger, W.; Blanckaert, K.; Leilei, G.

    2012-01-01

    Evolution of meanders, a complex morpho-dynamic process, has been the focus of research challenging river engineers for decades. The study replicates the natural evolution of meandering processes by coupling the Bank Erosion and Retreat Model (BERM, by Chen and Duan) with a nonlinear flow model (by

  7. Chute Formation and Iterative Adjustment in Large, Sand-Bed Meandering Rivers

    Science.gov (United States)

    Grenfell, M. C.; Aalto, R. E.; Nicholas, A.

    2011-12-01

    The meandering-braided continuum is a planform manifestation of excess available river energy; a balance between the energy of flow (commonly quantified as unit steam power or shear stress), and dynamic resistance due to bed material calibre and bank strength. Single-thread meandering rivers plot in part of the continuum defined by low excess available river energy, while braided rivers plot in part of the continuum defined by high excess available river energy. Planform patterns that are transitional between single-thread meandering and braided occur where chute channel formation is prolific. In this presentation we will elucidate the morphodynamic implications of chute formation for sinuosity and planform pattern in large, sand-bed meandering rivers. We draw on the results of recent research that applied binary logistic regression analysis to determine the possibility of predicting chute initiation based on attributes of meander bend character and dynamics (Grenfell et al., accepted, ESP&L). Regression models developed for the Strickland River, Papua New Guinea (54 bends), the lower Paraguay River, Paraguay/Argentina (45 bends), and the Beni River, Bolivia (114 bends), revealed that the probability of chute initiation at a meander bend is a function of the bend extension rate (the rate at which a bend elongates). Image analyses of all rivers and field observations from the Strickland suggest that the majority of chute channels form during scroll-slough development. Rapid extension is shown to favour chute initiation by breaking the continuity of point bar deposition and vegetation encroachment at the inner bank, resulting in widely-spaced scrolls with intervening sloughs that are positively aligned with primary over-bar flow. The rivers plot in order of increasing chute activity on an empirical meandering-braided pattern continuum (Kleinhans and van den Berg, 2011, ESP&L 36) defined by potential specific stream power (ωpv) and bedload calibre (D50). Increasing

  8. Single Na+ channels activated by veratridine and batrachotoxin

    Science.gov (United States)

    1987-01-01

    Voltage-sensitive Na+ channels from rat skeletal muscle plasma membrane vesicles were inserted into planar lipid bilayers in the presence of either of the alkaloid toxins veratridine (VT) or batrachotoxin (BTX). Both of these toxins are known to cause persistent activation of Na+ channels. With BTX as the channel activator, single channels remain open nearly all the time. Channels activated with VT open and close on a time scale of 1-10 s. Increasing the VT concentration enhances the probability of channel opening, primarily by increasing the rate constant of opening. The kinetics and voltage dependence of channel block by 21-sulfo-11-alpha-hydroxysaxitoxin are identical for VT and BTX, as is the ionic selectivity sequence determined by bi-ionic reversal potential (Na+ approximately Li+ greater than K+ greater than Rb+ greater than Cs+). However, there are striking quantitative differences in open channel conduction for channels in the presence of the two activators. Under symmetrical solution conditions, the single channel conductance for Na+ is about twice as high with BTX as with VT. Furthermore, the symmetrical solution single channel conductances show a different selectivity for BTX (Na+ greater than Li+ greater than K+) than for VT (Na+ greater than K+ greater than Li+). Open channel current-voltage curves in symmetrical Na+ and Li+ are roughly linear, while those in symmetrical K+ are inwardly rectifying. Na+ currents are blocked asymmetrically by K+ with both BTX and VT, but the voltage dependence of K+ block is stronger with BTX than with VT. The results show that the alkaloid neurotoxins not only alter the gating process of the Na+ channel, but also affect the structure of the open channel. We further conclude that the rate-determining step for conduction by Na+ does not occur at the channel's "selectivity filter," where poorly permeating ions like K+ are excluded. PMID:2435846

  9. Single-Channel Blind Estimation of Reverberation Parameters

    DEFF Research Database (Denmark)

    Doire, C.S.J.; Brookes, M. D.; Naylor, P. A.

    2015-01-01

    The reverberation of an acoustic channel can be characterised by two frequency-dependent parameters: the reverberation time and the direct-to-reverberant energy ratio. This paper presents an algorithm for blindly determining these parameters from a single-channel speech signal. The algorithm uses...

  10. Single channel analysis of membrane proteins in artificial bilayer membranes.

    Science.gov (United States)

    Bartsch, Philipp; Harsman, Anke; Wagner, Richard

    2013-01-01

    The planar lipid bilayer technique is a powerful experimental approach for electrical single channel recordings of pore-forming membrane proteins in a chemically well-defined and easily modifiable environment. Here we provide a general survey of the basic materials and procedures required to set up a robust bilayer system and perform electrophysiological single channel recordings of reconstituted proteins suitable for the in-depth characterization of their functional properties.

  11. Distributed meandering waveguides (DMWs) for novel photonic circuits (Conference Presentation)

    Science.gov (United States)

    Dag, Ceren B.; Anil, Mehmet Ali; Serpengüzel, Ali

    2017-05-01

    Meandering waveguide distributed feedback structures are novel integrated photonic lightwave and microwave circuit elements. Meandering waveguide distributed feedback structures with a variety of spectral responses can be designed for a variety of lightwave and microwave circuit element functions. Distributed meandering waveguide (DMW) structures [1] show a variety of spectral behaviors with respect to the number of meandering loop mirrors (MLMs) [2] used in their composition as well as their internal coupling constants (Cs). DMW spectral behaviors include Fano resonances, coupled resonator induced transparency (CRIT), notch, add-drop, comb, and hitless filters. What makes the DMW special is the self-coupling property intrinsic to the DMW's nature. The basic example of DMW's nature is motivated through the analogy between the so-called symmetric meandering resonator (SMR), which consists of two coupled MLMs, and the resonator enhanced Mach-Zehnder interferometer (REMZI) [3]. A SMR shows the same spectral characteristics of Fano resonances with its self-coupling property, similar to the single, distributed and binary self coupled optical waveguide (SCOW) resonators [4]. So far DMWs have been studied for their electric field intensity, phase [5] and phasor responses [6]. The spectral analysis is performed using the coupled electric field analysis and the generalization of single meandering loop mirrors to multiple meandering distributed feedback structures is performed with the transfer matrix method. The building block of the meandering waveguide structures, the meandering loop mirror (MLM), is the integrated analogue of the fiber optic loop mirrors. The meandering resonator (MR) is composed of two uncoupled MLM's. The meandering distributed feedback (MDFB) structure is the DFB of the MLM. The symmetric MR (SMR) is composed of two coupled MLM's, and has the characteristics of a Fano resonator in the general case, and tunable power divider or tunable hitless filter

  12. Imaging large cohorts of single ion channels and their activity

    Directory of Open Access Journals (Sweden)

    Katia eHiersemenzel

    2013-09-01

    Full Text Available As calcium is the most important signaling molecule in neurons and secretory cells, amongst many other cell types, it follows that an understanding of calcium channels and their regulation of exocytosis is of vital importance. Calcium imaging using calcium dyes such as Fluo3, or FRET-based dyes that have been used widely has provided invaluable information, which combined with modeling has estimated the sub-types of channels responsible for triggering the exocytotic machinery as well as inferences about the relative distances away from vesicle fusion sites these molecules adopt. Importantly, new super-resolution microscopy techniques, combined with novel Ca2+ indicators and imaginative imaging approaches can now define directly the nanoscale locations of very large cohorts of single channel molecules in relation to single vesicles. With combinations of these techniques the activity of individual channels can be visualized and quantified using novel Ca2+ indicators. Fluorescently labeled specific channel toxins can also be used to localize endogenous assembled channel tetramers. Fluorescence lifetime imaging microscopy and other single-photon-resolution spectroscopic approaches offer the possibility to quantify protein-protein interactions between populations of channels and the SNARE protein machinery for the first time. Together with simultaneous electrophysiology, this battery of quantitative imaging techniques has the potential to provide unprecedented detail describing the locations, dynamic behaviours, interactions and conductance activities of many thousands of channel molecules and vesicles in living cells.

  13. Monitoring single-channel water permeability in polarized cells.

    Science.gov (United States)

    Erokhova, Liudmila; Horner, Andreas; Kügler, Philipp; Pohl, Peter

    2011-11-18

    So far the determination of unitary permeability (p(f)) of water channels that are expressed in polarized cells is subject to large errors because the opening of a single water channel does not noticeably increase the water permeability of a membrane patch above the background. That is, in contrast to the patch clamp technique, where the single ion channel conductance may be derived from a single experiment, two experiments separated in time and/or space are required to obtain the single-channel water permeability p(f) as a function of the incremental water permeability (P(f,c)) and the number (n) of water channels that contributed to P(f,c). Although the unitary conductance of ion channels is measured in the native environment of the channel, p(f) is so far derived from reconstituted channels or channels expressed in oocytes. To determine the p(f) of channels from live epithelial monolayers, we exploit the fact that osmotic volume flow alters the concentration of aqueous reporter dyes adjacent to the epithelia. We measure these changes by fluorescence correlation spectroscopy, which allows the calculation of both P(f,c) and osmolyte dilution within the unstirred layer. Shifting the focus of the laser from the aqueous solution to the apical and basolateral membranes allowed the FCS-based determination of n. Here we validate the new technique by determining the p(f) of aquaporin 5 in Madin-Darby canine kidney cell monolayers. Because inhibition and subsequent activity rescue are monitored on the same sample, drug effects on exocytosis or endocytosis can be dissected from those on p(f).

  14. Spatially incoherent single channel digital Fourier holography.

    Science.gov (United States)

    Kelner, Roy; Rosen, Joseph

    2012-09-01

    We present a new method for recording digital Fourier holograms under incoherent illumination. A single exposure recorded by a digital camera is sufficient to record a real-valued hologram that encodes the complete three-dimensional properties of an object.

  15. Measuring Vtb via s-channel Single Top at ATLAS

    CERN Document Server

    O'Neil, D C; Lefebvre, M

    1999-01-01

    The production of single top quarks via the electroweak interaction promises to provide new opportunities to both test the Standard Model and search for new physics. In particular, electroweak top production provides the only means to directly measure the CKM matrix element Vtb, at ATLAS. The s-channel is the lowest rate, but best theoretically understood mechanism of electroweak top production. An evaluation of the potential for background suppression and Vtb measurement in this channel is presented. It is found that significant background suppression can be achieved and Vtb can be measured in the s-channel after 3 years of low luminosity running at LHC.

  16. Studies on positive conveying in helically channeled single screw extruders

    Directory of Open Access Journals (Sweden)

    L. Pan

    2012-07-01

    Full Text Available A solids conveying theory called double-flight driving theory was proposed for helically channeled single screw extruders. In the extruder, screw channel rotates against static barrel channel, which behaves as cooperative embedded twin-screws for the positive conveying. They turn as two parallel arc plates, between which an arc-plate solid-plug was assumed. By analyzing the forces on the solid-plug in the barrel channel and screw channel, the boundary conditions when the solid-plug is waived of being cut off on barrel wall, were found to have the capacity of the positive conveying. Experimental data were obtained using a specially designed extruder with a helically channeled barrel in the feeding zone and a pressure-adjustable die. The effects of the barrel channel geometry and friction coefficients on the conveying mechanism were presented and compared with the experimental results. The simulations showed that the positive conveying could be achieved after optimizing extruder designs. Compared with the traditional design with the friction-drag conveying, the throughput is higher while screw torque and energy consumption are decreased. Besides, the design criteria of the barrel channel were also discussed.

  17. Simultaneous optical and electrical recording of single gramicidin channels.

    Science.gov (United States)

    Borisenko, V; Lougheed, T; Hesse, J; Füreder-Kitzmüller, E; Fertig, N; Behrends, J C; Woolley, G A; Schütz, G J

    2003-01-01

    We report here an approach for simultaneous fluorescence imaging and electrical recording of single ion channels in planar bilayer membranes. As a test case, fluorescently labeled (Cy3 and Cy5) gramicidin derivatives were imaged at the single-molecule level using far-field illumination and cooled CCD camera detection. Gramicidin monomers were observed to diffuse in the plane of the membrane with a diffusion coefficient of 3.3 x 10(-8) cm(2)s(-1). Simultaneous electrical recording detected gramicidin homodimer (Cy3/Cy3, Cy5/Cy5) and heterodimer (Cy3/Cy5) channels. Heterodimer formation was observed optically by the appearance of a fluorescence resonance energy transfer (FRET) signal (irradiation of Cy3, detection of Cy5). The number of FRET signals was significantly smaller than the number of Cy3 signals (Cy3 monomers plus Cy3 homodimers) as expected. The number of FRET signals increased with increasing channel activity. In numerous cases the appearance of a FRET signal was observed to correlate with a channel opening event detected electrically. The heterodimers also diffused in the plane of the membrane with a diffusion coefficient of 3.0 x 10(-8) cm(2)s(-1). These experiments demonstrate the feasibility of simultaneous optical and electrical detection of structural changes in single ion channels as well as suggesting strategies for improving the reliability of such measurements.

  18. Photodynamic membrane damage at the level of single ion channels.

    Science.gov (United States)

    Kunz, L; Stark, G

    1997-07-05

    Illumination of cellular membranes by visible light in the presence of appropriate photosensitizers is known to inactivate specific ionic pathways and to increase the unspecific leak conductance of the membranes. While previous studies have concentrated on the macroscopic ionic currents, the present study separates the two phenomena at the microscopic level. Using opossum kidney (OK) cells as epithelial model system and photofrin II as sensitizer, the patch-clamp technique in inside-out configuration has been applied to show the inactivation of single ion channels immediately after start of illumination and the subsequent strong increase of the leak conductance. Inactivation is shown for two kinds of channels: the large-conductance Ca2+-dependent K+ channel (maxi-K(Ca)) and the stretch-activated nonselective cation channel (SA-cat).

  19. Single-molecule denaturation mapping of DNA in nanofluidic channels

    DEFF Research Database (Denmark)

    Reisner, Walter; Larsen, Niels Bent; Silahtaroglu, Asli

    2010-01-01

    Here we explore the potential power of denaturation mapping as a single-molecule technique. By partially denaturing YOYO (R)-1-labeled DNA in nanofluidic channels with a combination of formamide and local heating, we obtain a sequence-dependent "barcode" corresponding to a series of local dips...

  20. Single channel in-line multimodal digital holography.

    Science.gov (United States)

    Rivenson, Yair; Katz, Barak; Kelner, Roy; Rosen, Joseph

    2013-11-15

    We present a new single channel in-line setup for holographic recording that can properly record various objects that cannot be recorded by the Gabor holographic method. This configuration allows the recording of holograms based on several modalities while addressing important issues of the original Gabor setup, including the well-known twin-image problem and the weak scattering condition.

  1. Three-dimensional (3-D) video systems: bi-channel or single-channel optics?

    Science.gov (United States)

    van Bergen, P; Kunert, W; Buess, G F

    1999-11-01

    This paper presents the results of a comparison between two different three-dimensional (3-D) video systems, one with single-channel optics, the other with bi-channel optics. The latter integrates two lens systems, each transferring one half of the stereoscopic image; the former uses only one lens system, similar to a two-dimensional (2-D) endoscope, which transfers the complete stereoscopic picture. In our training centre for minimally invasive surgery, surgeons were involved in basic and advanced laparoscopic courses using both a 2-D system and the two 3-D video systems. They completed analog scale questionnaires in order to record a subjective impression of the relative convenience of operating in 2-D and 3-D vision, and to identify perceived deficiencies in the 3-D system. As an objective test, different experimental tasks were developed, in order to measure performance times and to count pre-defined errors made while using the two 3-D video systems and the 2-D system. Using the bi-channel optical system, the surgeon has a heightened spatial perception, and can work faster and more safely than with a single-channel system. However, single-channel optics allow the use of an angulated endoscope, and the free rotation of the optics relative to the camera, which is necessary for some operative applications.

  2. Single Particle Nanoplasmonic Sensing in Individual Nanofluidic Channels.

    Science.gov (United States)

    Fritzsche, Joachim; Albinsson, David; Fritzsche, Michael; Antosiewicz, Tomasz J; Westerlund, Fredrik; Langhammer, Christoph

    2016-12-14

    Nanoplasmonics allows label-free optical sensing and spectroscopy at the single nanoparticle level by exploiting plasmonic excitations in metal nanoparticles. Nanofluidics offers exclusive possibilities for applying and controlling fluid flow and mass transport at the nanoscale and toward nanosized objects. Here, we combine these two concepts in a single device, by integrating single particle nanoplasmonic sensing with nanofluidics using advanced nanofabrication. The developed devices enable on-chip referenced parallel single particle nanoplasmonic sensing inside multiple individual nanofluidic channels with dimensions down to the 100 nm range. Beyond detailed discussion of the nanofabrication, general device characterization, and parallelized single particle plasmonic readout concepts, we demonstrate device function on two examples: (i) in situ measurements of local buffer concentrations inside a nanofluidic channel; (ii) real time binding kinetics of alkanethiol molecules to a single plasmonic nanonatenna sensor in a single nanochannel. Our concept thus provides a powerful solution for controlling mass transport to and from individual (plasmonic) nanoparticles, which in a long-term perspective offers unique opportunities for label-free detection of analyte molecules at low concentrations and for fundamental studies of fluids in extreme confinement.

  3. Joint Single-Channel Speech Separation and Speaker Identification

    DEFF Research Database (Denmark)

    Mowlaee, Pejman; Saeidi, Rahim; Tan, Zheng-Hua

    2010-01-01

    In this paper, we propose a closed loop system to improve the performance of single-channel speech separation in a speaker independent scenario. The system is composed of two interconnected blocks: a separation block and a speaker identiſcation block. The improvement is accomplished by incorporat......In this paper, we propose a closed loop system to improve the performance of single-channel speech separation in a speaker independent scenario. The system is composed of two interconnected blocks: a separation block and a speaker identiſcation block. The improvement is accomplished...... by incorporating the speaker identities found by the speaker identiſcation block as additional information for the separation block, which converts the speaker-independent separation problem to a speaker-dependent one where the speaker codebooks are known. Simulation results show that the closed loop system...

  4. Evaluation of an automated single-channel sleep staging algorithm

    OpenAIRE

    Kaplan, Richard; Wang,Ying; Loparo,Kenneth; Kelly,Monica

    2015-01-01

    Ying Wang,1 Kenneth A Loparo,1,2 Monica R Kelly,3 Richard F Kaplan1 1General Sleep Corporation, Euclid, OH, 2Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH, 3Department of Psychology, University of Arizona, Tucson, AZ, USA Background: We previously published the performance evaluation of an automated electroencephalography (EEG)-based single-channel sleep–wake detection algorithm called Z-ALG used by the Zmachine® s...

  5. Application of meandering centreline migration modelling and object-based approach of Long Nab member

    Science.gov (United States)

    Saadi, Saad

    2017-04-01

    Characterizing the complexity and heterogeneity of the geometries and deposits in meandering river system is an important concern for the reservoir modelling of fluvial environments. Re-examination of the Long Nab member in the Scalby formation of the Ravenscar Group (Yorkshire, UK), integrating digital outcrop data and forward modelling approaches, will lead to a geologically realistic numerical model of the meandering river geometry. The methodology is based on extracting geostatistics from modern analogous, meandering rivers that exemplify both the confined and non-confined meandering point bars deposits and morphodynamics of Long Nab member. The parameters derived from the modern systems (i.e. channel width, amplitude, radius of curvature, sinuosity, wavelength, channel length and migration rate) are used as a statistical control for the forward simulation and resulting object oriented channel models. The statistical data derived from the modern analogues is multi-dimensional in nature, making analysis difficult. We apply data mining techniques such as parallel coordinates to investigate and identify the important relationships within the modern analogue data, which can then be used drive the development of, and as input to the forward model. This work will increase our understanding of meandering river morphodynamics, planform architecture and stratigraphic signature of various fluvial deposits and features. We will then use these forward modelling based channel objects to build reservoir models, and compare the behaviour of the forward modelled channels with traditional object modelling in hydrocarbon flow simulations.

  6. Simultaneous Optical and Electrical Recording of Single Gramicidin Channels

    OpenAIRE

    Borisenko, V.; Lougheed, T.; Hesse, J.; Füreder-Kitzmüller, E.; Fertig, N.; Behrends, J.C.; Woolley, G.A.; Schütz, G.J.

    2003-01-01

    We report here an approach for simultaneous fluorescence imaging and electrical recording of single ion channels in planar bilayer membranes. As a test case, fluorescently labeled (Cy3 and Cy5) gramicidin derivatives were imaged at the single-molecule level using far-field illumination and cooled CCD camera detection. Gramicidin monomers were observed to diffuse in the plane of the membrane with a diffusion coefficient of 3.3 × 10−8 cm2s−1. Simultaneous electrical recording detected gramicidi...

  7. Improvement of Source Number Estimation Method for Single Channel Signal.

    Directory of Open Access Journals (Sweden)

    Zhi Dong

    Full Text Available Source number estimation methods for single channel signal have been investigated and the improvements for each method are suggested in this work. Firstly, the single channel data is converted to multi-channel form by delay process. Then, algorithms used in the array signal processing, such as Gerschgorin's disk estimation (GDE and minimum description length (MDL, are introduced to estimate the source number of the received signal. The previous results have shown that the MDL based on information theoretic criteria (ITC obtains a superior performance than GDE at low SNR. However it has no ability to handle the signals containing colored noise. On the contrary, the GDE method can eliminate the influence of colored noise. Nevertheless, its performance at low SNR is not satisfactory. In order to solve these problems and contradictions, the work makes remarkable improvements on these two methods on account of the above consideration. A diagonal loading technique is employed to ameliorate the MDL method and a jackknife technique is referenced to optimize the data covariance matrix in order to improve the performance of the GDE method. The results of simulation have illustrated that the performance of original methods have been promoted largely.

  8. Gating kinetics of batrachotoxin-modified sodium channels in neuroblastoma cells determined from single-channel measurements

    OpenAIRE

    Huang, L.Y.; Moran, N.; Ehrenstein, G.

    1984-01-01

    We have observed the opening and closing of single batrachotoxin (BTX)-modified sodium channels in neuroblastoma cells using the patch-clamp method. The conductance of a single BTX-modified channel is approximately 10 pS. At a given membrane potential, the channels are open longer than are normal sodium channels. As is the case for normal sodium channels, the open dwell times become longer as the membrane is depolarized. For membrane potentials more negative than about -70 mV, histograms of b...

  9. A Timing Single Channel Analyzer with pileup rejection

    International Nuclear Information System (INIS)

    Lauch, J.; Nachbar, H.U.

    1981-07-01

    A Timing Single Channel Analyzer is described as normally used in nuclear physics applications for measuring certain ranges of energy spectra. The unit accepts unipolar or bipolar gaussian shaped or rectangular pulses and includes a special pileup rejection circuit. Because of its good timing performance high resolution timing and coincidence measurements are possible. The differential analyzer, trigger and timing modes and the function of external strobe and gate signals are explained. Parts of the circuit are illustrated by help of block diagrams and pulse schematics. An essential part of the unit is the pileup rejection circuit. Following theoretical reflections the circuit is described and some measurement results are reported. (orig.) [de

  10. Channeling effect studies in V3Si single crystals

    International Nuclear Information System (INIS)

    Meyer, O.

    1978-01-01

    Angular scans through the [100] and [110] channeling directions in V 3 Si have been performed using elastically scattered He ions for the V-rows and the 28 Si(d,p 8 ) 29 Si reaction for the Si-rows. The amplitude of thermal vibration perpendicular to the V-chains was found to be larger than that at 45 0 to them. The Si atoms however vibrate isotropically. The use of multi-row potentials instead of single-row potentials leads to better overall agreement between measured and calculated critical angles. (Auth.)

  11. Synchronization of uncertain chaotic systems using a single transmission channel

    International Nuclear Information System (INIS)

    Feng Yong; Yu Xinghuo; Sun Lixia

    2008-01-01

    This paper proposes a robust sliding mode observer for synchronization of uncertain chaotic systems with multi-nonlinearities. A new control strategy is proposed for the construction of the robust sliding mode observer, which can avoid the strict conditions in the design process of Walcott-Zak observer. A new method of multi-dimensional signal transmission via single transmission channel is proposed and applied to chaos synchronization of uncertain chaotic systems with multi-nonlinearities. The simulation results are presented to validate the method

  12. Modification of meander migration by bank failures

    Science.gov (United States)

    Motta, D.; Langendoen, E. J.; Abad, J. D.; García, M. H.

    2014-05-01

    Meander migration and planform evolution depend on the resistance to erosion of the floodplain materials. To date, research to quantify meandering river adjustment has largely focused on resistance to erosion properties that vary horizontally. This paper evaluates the combined effect of horizontal and vertical floodplain material heterogeneity on meander migration by simulating fluvial erosion and cantilever and planar bank mass failure processes responsible for bank retreat. The impact of stream bank failures on meander migration is conceptualized in our RVR Meander model through a bank armoring factor associated with the dynamics of slump blocks produced by cantilever and planar failures. Simulation periods smaller than the time to cutoff are considered, such that all planform complexity is caused by bank erosion processes and floodplain heterogeneity and not by cutoff dynamics. Cantilever failure continuously affects meander migration, because it is primarily controlled by the fluvial erosion at the bank toe. Hence, it impacts migration rates and meander shapes through the horizontal and vertical distribution of erodibility of floodplain materials. Planar failures are more episodic. However, in floodplain areas characterized by less cohesive materials, they can affect meander evolution in a sustained way and produce preferential migration patterns. Model results show that besides the hydrodynamics, bed morphology and horizontal floodplain heterogeneity, floodplain stratigraphy can significantly affect meander evolution, both in terms of migration rates and planform shapes. Specifically, downstream meander migration can either increase or decrease with respect to the case of a homogeneous floodplain; lateral migration generally decreases as result of bank protection due to slump blocks; and the effect on bend skewness depends on the location and volumes of failed bank material caused by cantilever and planar failures along the bends, with possible achievement of

  13. Mimicking multichannel scattering with single-channel approaches

    Science.gov (United States)

    Grishkevich, Sergey; Schneider, Philipp-Immanuel; Vanne, Yulian V.; Saenz, Alejandro

    2010-02-01

    The collision of two atoms is an intrinsic multichannel (MC) problem, as becomes especially obvious in the presence of Feshbach resonances. Due to its complexity, however, single-channel (SC) approximations, which reproduce the long-range behavior of the open channel, are often applied in calculations. In this work the complete MC problem is solved numerically for the magnetic Feshbach resonances (MFRs) in collisions between generic ultracold Li6 and Rb87 atoms in the ground state and in the presence of a static magnetic field B. The obtained MC solutions are used to test various existing as well as presently developed SC approaches. It was found that many aspects even at short internuclear distances are qualitatively well reflected. This can be used to investigate molecular processes in the presence of an external trap or in many-body systems that can be feasibly treated only within the framework of the SC approximation. The applicability of various SC approximations is tested for a transition to the absolute vibrational ground state around an MFR. The conformance of the SC approaches is explained by the two-channel approximation for the MFR.

  14. Mimicking multichannel scattering with single-channel approaches

    International Nuclear Information System (INIS)

    Grishkevich, Sergey; Schneider, Philipp-Immanuel; Vanne, Yulian V.; Saenz, Alejandro

    2010-01-01

    The collision of two atoms is an intrinsic multichannel (MC) problem, as becomes especially obvious in the presence of Feshbach resonances. Due to its complexity, however, single-channel (SC) approximations, which reproduce the long-range behavior of the open channel, are often applied in calculations. In this work the complete MC problem is solved numerically for the magnetic Feshbach resonances (MFRs) in collisions between generic ultracold 6 Li and 87 Rb atoms in the ground state and in the presence of a static magnetic field B. The obtained MC solutions are used to test various existing as well as presently developed SC approaches. It was found that many aspects even at short internuclear distances are qualitatively well reflected. This can be used to investigate molecular processes in the presence of an external trap or in many-body systems that can be feasibly treated only within the framework of the SC approximation. The applicability of various SC approximations is tested for a transition to the absolute vibrational ground state around an MFR. The conformance of the SC approaches is explained by the two-channel approximation for the MFR.

  15. Acute single channel EEG predictors of cognitive function after stroke.

    Directory of Open Access Journals (Sweden)

    Anna Aminov

    Full Text Available Early and accurate identification of factors that predict post-stroke cognitive outcome is important to set realistic targets for rehabilitation and to guide patients and their families accordingly. However, behavioral measures of cognition are difficult to obtain in the acute phase of recovery due to clinical factors (e.g. fatigue and functional barriers (e.g. language deficits. The aim of the current study was to test whether single channel wireless EEG data obtained acutely following stroke could predict longer-term cognitive function.Resting state Relative Power (RP of delta, theta, alpha, beta, delta/alpha ratio (DAR, and delta/theta ratio (DTR were obtained from a single electrode over FP1 in 24 participants within 72 hours of a first-ever stroke. The Montreal Cognitive Assessment (MoCA was administered at 90-days post-stroke. Correlation and regression analyses were completed to identify relationships between 90-day cognitive function and electrophysiological data, neurological status, and demographic characteristics at admission.Four acute qEEG indices demonstrated moderate to high correlations with 90-day MoCA scores: DTR (r = -0.57, p = 0.01, RP theta (r = 0.50, p = 0.01, RP delta (r = -0.47, p = 0.02, and DAR (r = -0.45, p = 0.03. Acute DTR (b = -0.36, p < 0.05 and stroke severity on admission (b = -0.63, p < 0.01 were the best linear combination of predictors of MoCA scores 90-days post-stroke, accounting for 75% of variance.Data generated by a single pre-frontal electrode support the prognostic value of acute DAR, and identify DTR as a potential marker of post-stroke cognitive outcome. Use of single channel recording in an acute clinical setting may provide an efficient and valid predictor of cognitive function after stroke.

  16. Single-channel stereoscopic ophthalmology microscope based on TRD

    Science.gov (United States)

    Radfar, Edalat; Park, Jihoon; Lee, Sangyeob; Ha, Myungjin; Yu, Sungkon; Jang, Seulki; Jung, Byungjo

    2016-03-01

    A stereoscopic imaging modality was developed for the application of ophthalmology surgical microscopes. A previous study has already introduced a single-channel stereoscopic video imaging modality based on a transparent rotating deflector (SSVIM-TRD), in which two different view angles, image disparity, are generated by imaging through a transparent rotating deflector (TRD) mounted on a stepping motor and is placed in a lens system. In this case, the image disparity is a function of the refractive index and the rotation angle of TRD. Real-time single-channel stereoscopic ophthalmology microscope (SSOM) based on the TRD is improved by real-time controlling and programming, imaging speed, and illumination method. Image quality assessments were performed to investigate images quality and stability during the TRD operation. Results presented little significant difference in image quality in terms of stability of structural similarity (SSIM). A subjective analysis was performed with 15 blinded observers to evaluate the depth perception improvement and presented significant improvement in the depth perception capability. Along with all evaluation results, preliminary results of rabbit eye imaging presented that the SSOM could be utilized as an ophthalmic operating microscopes to overcome some of the limitations of conventional ones.

  17. Testing the single degenerate channel for supernova Ia

    Science.gov (United States)

    Parsons, Steven

    2014-10-01

    The progenitors of supernova Ia are close binaries containing white dwarfs. Of crucial importance to the evolution of these systems is how much material the white dwarf can stably accrete and hence grow in mass. This occurs during a short-lived intense phase of mass transfer known as the super soft source (SSS) phase. The short duration of this phase and large extinction to soft X-rays means that only a handful are known in our Galaxy. Far more can be learned from the underlying SSS progenitor population of close white dwarf plus FGK type binaries. Unfortunately, these systems are hard to find since the main-sequence stars completely outshine the white dwarfs at optical wavelengths. Because of this, there are currently no known close white dwarf binaries with F, G or early K type companions, making it impossible to determine the contribution of the single degenerate channel towards supernova Ia. Using the GALEX and RAVE surveys we have now identified the first large sample of FGK stars with UV excesses, a fraction of which are these illusive, close systems. Following an intense ground based spectroscopic investigation of these systems, we have identified 5 definite close binaries, with periods of less than a few days. Here we apply for COS spectroscopic observations to measure the mass and temperature of the white dwarfs in order to determine the future evolution of these systems. This will provide a crucial test for the single degenerate channel towards supernova Ia.

  18. Distributed sensing: multiple capacitive stretch sensors on a single channel

    Science.gov (United States)

    Tairych, Andreas; Anderson, Iain A.

    2017-04-01

    "Soft, stretchable, and unobtrusive". These are some of the attributes frequently associated with capacitive dielectric elastomer (DE) sensors for body motion capture. While the sensors themselves are soft and elastic, they require rigid peripheral components for capacitance measurement. Each sensor is connected to a separate channel on the sensing circuitry through its own set of wires. In wearable applications with large numbers of sensors, this can lead to a considerable circuit board footprint, and cumbersome wiring. The additional equipment can obstruct movement and alter user behaviour. Previous work has demonstrated how a transmission line model can be applied to localise deformation on a single DE sensor. Building on this approach, we have developed a distributed sensing method by arranging capacitive DE sensors and external resistors to form a transmission line, which is connected to a single sensing channel with only one set of wires. The sensors are made from conductive fabric electrodes, and silicone dielectrics, and the external resistors are off-the-shelf metal film resistors. Excitation voltages with different frequencies are applied to the transmission line. The lumped transmission line capacitances at these frequencies are passed on to a mathematical model that calculates individual sensor capacitance changes. The prototype developed for this study is capable of obtaining separate readings for simultaneously stretched sensors.

  19. Not Only Enthalpy: Large Entropy Contribution to Ion Permeation Barriers in Single-File Channels

    OpenAIRE

    Portella, Guillem; Hub, Jochen S.; Vesper, Martin D.; de Groot, Bert L.

    2008-01-01

    The effect of channel length on the barrier for potassium ion permeation through single-file channels has been studied by means of all-atom molecular dynamics simulations. Using series of peptidic gramicidin-like and simplified ring-structured channels, both embedded in model membranes, we obtained two distinct types of behavior: saturation of the central free energy barriers for peptidic channels and a linear increase in simplified ring-structured channels with increasing channel length. The...

  20. Evaluation of an automated single-channel sleep staging algorithm

    Science.gov (United States)

    Wang, Ying; Loparo, Kenneth A; Kelly, Monica R; Kaplan, Richard F

    2015-01-01

    Background We previously published the performance evaluation of an automated electroencephalography (EEG)-based single-channel sleep–wake detection algorithm called Z-ALG used by the Zmachine® sleep monitoring system. The objective of this paper is to evaluate the performance of a new algorithm called Z-PLUS, which further differentiates sleep as detected by Z-ALG into Light Sleep, Deep Sleep, and Rapid Eye Movement (REM) Sleep, against laboratory polysomnography (PSG) using a consensus of expert visual scorers. Methods Single night, in-lab PSG recordings from 99 subjects (52F/47M, 18–60 years, median age 32.7 years), including both normal sleepers and those reporting a variety of sleep complaints consistent with chronic insomnia, sleep apnea, and restless leg syndrome, as well as those taking selective serotonin reuptake inhibitor/serotonin–norepinephrine reuptake inhibitor antidepressant medications, previously evaluated using Z-ALG were re-examined using Z-PLUS. EEG data collected from electrodes placed at the differential-mastoids (A1–A2) were processed by Z-ALG to determine wake and sleep, then those epochs detected as sleep were further processed by Z-PLUS to differentiate into Light Sleep, Deep Sleep, and REM. EEG data were visually scored by multiple certified polysomnographic technologists according to the Rechtschaffen and Kales criterion, and then combined using a majority-voting rule to create a PSG Consensus score file for each of the 99 subjects. Z-PLUS output was compared to the PSG Consensus score files for both epoch-by-epoch (eg, sensitivity, specificity, and kappa) and sleep stage-related statistics (eg, Latency to Deep Sleep, Latency to REM, Total Deep Sleep, and Total REM). Results Sensitivities of Z-PLUS compared to the PSG Consensus were 0.84 for Light Sleep, 0.74 for Deep Sleep, and 0.72 for REM. Similarly, positive predictive values were 0.85 for Light Sleep, 0.78 for Deep Sleep, and 0.73 for REM. Overall, kappa agreement of 0

  1. Single sodium channels from human ventricular muscle in planar lipid bilayers

    NARCIS (Netherlands)

    Wartenberg, H. C.; Wartenberg, J. P.; Urban, B. W.

    2001-01-01

    Sodium channels from human ventricular muscle membrane vesicles were incorporated into planar lipid bilayers and the steady-state behavior of single sodium channels were examined in the presence of batrachotoxin. In symmetrical 500 mM NaCl the averaged single channel conductance was 24.7 +/- 1.3 pS

  2. A New MEMS Gyroscope Used for Single-Channel Damping.

    Science.gov (United States)

    Zhang, Zengping; Zhang, Wei; Zhang, Fuxue; Wang, Biao

    2015-04-30

    The silicon micromechanical gyroscope, which will be introduced in this paper, represents a novel MEMS gyroscope concept. It is used for the damping of a single-channel control system of rotating aircraft. It differs from common MEMS gyroscopes in that does not have a drive structure, itself, and only has a sense structure. It is installed on a rotating aircraft, and utilizes the aircraft spin to make its sensing element obtain angular momentum. When the aircraft is subjected to an angular rotation, a periodic Coriolis force is induced in the direction orthogonal to both the angular momentum and the angular velocity input axis. This novel MEMS gyroscope can thus sense angular velocity inputs. The output sensing signal is exactly an amplitude-modulation signal. Its envelope is proportional to the input angular velocity, and the carrier frequency corresponds to the spin frequency of the rotating aircraft, so the MEMS gyroscope can not only sense the transverse angular rotation of an aircraft, but also automatically change the carrier frequency over the change of spin frequency, making it very suitable for the damping of a single-channel control system of a rotating aircraft. In this paper, the motion equation of the MEMS gyroscope has been derived. Then, an analysis has been carried to solve the motion equation and dynamic parameters. Finally, an experimental validation has been done based on a precision three axis rate table. The correlation coefficients between the tested data and the theoretical values are 0.9969, 0.9872 and 0.9842, respectively. These results demonstrate that both the design and sensing mechanism are correct.

  3. Non stochastic distribution of single channels in planar lipid bilayers.

    Science.gov (United States)

    Krasilnikov, O V; Merzliak, P G; Yuldasheva, L N; Nogueira, R A; Rodrigues, C G

    1995-02-15

    The selectivity of the planar lipid bilayers modified by two channel-forming proteins (alpha-toxin S. aureus and colicin Ia) was examined. It was established that in all cases the value of zero current potential depended on the amount of open ion channels and increased with the number of channels (from one to about 5-7). These facts point out both the interactions among ion channels and their non stochastic distribution on the membrane surface.

  4. Classification of four-class motor imagery employing single-channel electroencephalography.

    Directory of Open Access Journals (Sweden)

    Sheng Ge

    Full Text Available With advances in brain-computer interface (BCI research, a portable few- or single-channel BCI system has become necessary. Most recent BCI studies have demonstrated that the common spatial pattern (CSP algorithm is a powerful tool in extracting features for multiple-class motor imagery. However, since the CSP algorithm requires multi-channel information, it is not suitable for a few- or single-channel system. In this study, we applied a short-time Fourier transform to decompose a single-channel electroencephalography signal into the time-frequency domain and construct multi-channel information. Using the reconstructed data, the CSP was combined with a support vector machine to obtain high classification accuracies from channels of both the sensorimotor and forehead areas. These results suggest that motor imagery can be detected with a single channel not only from the traditional sensorimotor area but also from the forehead area.

  5. Emotion classification using single-channel scalp-EEG recording.

    Science.gov (United States)

    Jalilifard, Amir; Brigante Pizzolato, Ednaldo; Kafiul Islam, Md

    2016-08-01

    Several studies have found evidence for corticolimbic Theta electroencephalographic (EEG) oscillation in the neural processing of visual stimuli perceived as fear or threatening scene. Recent studies showed that neural oscillations' patterns in Theta, Alpha, Beta and Gamma sub-bands play a main role in brain's emotional processing. The main goal of this study is to classify two different emotional states by means of EEG data recorded through a single-electrode EEG headset. Nineteen young subjects participated in an EEG experiment while watching a video clip that evoked three emotional states: neutral, relaxation and scary. Following each video clip, participants were asked to report on their subjective affect by giving a score between 0 to 10. First, recorded EEG data were preprocessed by stationary wavelet transform (SWT) based denoising to remove artifacts. Afterward, the distribution of power in time-frequency space was obtained using short-time Fourier transform (STFT) and then, the mean value of energy was calculated for each EEG sub-band. Finally, 46 features, as the mean energy of frequency bands between 4 and 50 Hz, containing 689 instances - for each subject -were collected in order to classify the emotional states. Our experimental results show that EEG dynamics induced by horror and relaxing movies can be classified with average classification rate of 92% using support vector machine (SVM) classifier. We also compared the performance of SVM to K-nearest neighbors (K-NN). The results show that K-NN achieves a better classification rate by 94% accuracy. The findings of this work are expected to pave the way to a new horizon in neuroscience by proving the point that only single-channel EEG data carry enough information for emotion classification.

  6. [Compared Markov with fractal models by using single-channel experimental and simulation data].

    Science.gov (United States)

    Lan, Tonghan; Wu, Hongxiu; Lin, Jiarui

    2006-10-01

    The gating mechanical kinetical of ion channels has been modeled as a Markov process. In these models it is assumed that the channel protein has a small number of discrete conformational states and kinetic rate constants connecting these states are constant, the transition rate constants among the states is independent both of time and of the previous channel activity. It is assumed in Liebovitch's fractal model that the channel exists in an infinite number of energy states, consequently, transitions from one conductance state to another would be governed by a continuum of rate constants. In this paper, a statistical comparison is presented of Markov and fractal models of ion channel gating, the analysis is based on single-channel data from ion channel voltage-dependence K+ single channel of neuron cell and simulation data from three-states Markov model.

  7. Meandering Rivers: How Important is Lateral Variability for Species Persistence?

    Science.gov (United States)

    Jin, Yu; Lutscher, Frithjof; Pei, Yuan

    2017-12-01

    Models for population dynamics in rivers and streams have highlighted the importance of spatial and temporal variations for population persistence. We present a novel model that considers the longitudinal variation as introduced by the sinuosity of a meandering river where a main channel is laterally extended to point bars in bends. These regions offer different habitat conditions for aquatic populations and therefore may enhance population persistence. Our model is a nonstandard reaction-advection-diffusion model where the domain of definition consists of the real line (representing the main channel) with periodically added intervals (representing the point bars). We give an existence and uniqueness proof for solutions of the equations. We then study population persistence as the (in-) stability of the trivial solution and population spread as the minimal wave speed of traveling periodic waves. We conduct a sensitivity analysis to highlight the importance of each parameter on the model outcome. We find that sinuosity can enhance species persistence.

  8. Low SNR capacity for MIMO Rician and Rayleigh-product fading channels with single co-channel interferer and noise

    KAUST Repository

    Zhong, Caijun

    2010-09-01

    This paper studies the ergodic capacity of multiple-input multiple-output (MIMO) systems with a single co-channel interferer in the low signal-to-noise-ratio (SNR) regime. Two MIMO models namely Rician and Rayleigh-product channels are investigated. Exact analytical expressions for the minimum energy per information bit, {Eb/N0min, and wideband slope, S0, are derived for both channels. Our results show that the minimum energy per information bit is the same for both channels while their wideband slopes differ significantly. Further, the impact of the numbers of transmit and receive antennas, the Rician K factor, the channel mean matrix and the interference-to-noise-ratio (INR) on the capacity, is addressed. Results indicate that interference degrades the capacity by increasing the required minimum energy per information bit and reducing the wideband slope. Simulation results validate our analytical results. © 2010 IEEE.

  9. Single Ih channels in pyramidal neuron dendrites: properties, distribution, and impact on action potential output

    NARCIS (Netherlands)

    Kole, Maarten H. P.; Hallermann, Stefan; Stuart, Greg J.

    2006-01-01

    The hyperpolarization-activated cation current (Ih) plays an important role in regulating neuronal excitability, yet its native single-channel properties in the brain are essentially unknown. Here we use variance-mean analysis to study the properties of single Ih channels in the apical dendrites of

  10. Dynamic meandering in response to upstream perturbations and floodplain formation

    NARCIS (Netherlands)

    Schuurman, F.; Shimizu, Y.; Iwasaki, T.; Kleinhans, M. G.

    2016-01-01

    River meandering results from spatially alternating bank erosion and bar growth. Recent flume experiments and theory suggest that a continuous inflow perturbation is a requirement for sustained meandering. Furthermore, flume experiments suggest that bar-floodplain conversion is an additional

  11. LHC BLM Single Channel Connectivity Test using the Standard Installation

    CERN Document Server

    Emery, J; Effinger, E; Ferioli, G; Zamantzas, C; Ikeda, H; Verhagen, E

    2009-01-01

    For the LHC Beam Loss Measurement system (BLM), the high voltage supply of the ionisation chambers and the secondary emission detectors is used to test their connectivity. A harmonic modulation of 0.03 Hz results in a current signal of about 100pA measured by the beam loss acquisition electronics. The signal is analyzed and the measured amplitude and phase are compared with individual channel limits for the 4000 channels. It is foreseen to execute an automatic procedure for all channels every 12 hours which takes about 20 minutes. The paper will present the design of the system, the circuit simulations, measurements of systematic dependencies of different channels and the reproducibility of the amplitude and phase measurements.

  12. Characteristics of a single-channel superconducting flux flow transistor fabricated by an AFM modification technique

    International Nuclear Information System (INIS)

    Ko, Seokcheol; Kim, Seong-Jong

    2007-01-01

    The demand for high performance, integrity, and miniaturization in the area of electronic and mechanic devices has drawn interest in the fabrication of nanostructures. However, it is difficult to fabricate the channel with nano-scale using a conventional photography techniques. AFM anodization technique is a maskless process and effective method to overcome the difficulty in fabricating a nano-scale channel. In this paper, we first present a new fabrication of a single-channel SFFT using a selective oxidation process induced by an AFM probe. The modified channel was investigated by electron probe microanalyzer (EPMA) to find the compositional variation of the transformed region. In order to confirm the operation of a single-channel SFFT, we measured the voltage-current characteristics at the temperature of liquid nitrogen by an I-V automatic measurement system. Our results indicate that the single-channel SFFT having effect as a weak link is effectively fabricated by an AFM lithography process

  13. Mobility-limiting mechanisms in single and dual channel strained Si/SiGe MOSFETs

    International Nuclear Information System (INIS)

    Olsen, S.H.; Dobrosz, P.; Escobedo-Cousin, E.; Bull, S.J.; O'Neill, A.G.

    2005-01-01

    Dual channel strained Si/SiGe CMOS architectures currently receive great attention due to maximum performance benefits being predicted for both n- and p-channel MOSFETs. Epitaxial growth of a compressively strained SiGe layer followed by tensile strained Si can create a high mobility buried hole channel and a high mobility surface electron channel on a single relaxed SiGe virtual substrate. However, dual channel n-MOSFETs fabricated using a high thermal budget exhibit compromised mobility enhancements compared with single channel devices, in which both electron and hole channels form in strained Si. This paper investigates the mobility-limiting mechanisms of dual channel structures. The first evidence of increased interface roughness due to the introduction of compressively strained SiGe below the tensile strained Si channel is presented. Interface corrugations degrade electron mobility in the strained Si. Roughness measurements have been carried out using AFM and TEM. Filtering AFM images allowed roughness at wavelengths pertinent to carrier transport to be studied and the results are in agreement with electrical data. Furthermore, the first comparison of strain measurements in the surface channels of single and dual channel architectures is presented. Raman spectroscopy has been used to study channel strain both before and after processing and indicates that there is no impact of the buried SiGe layer on surface macrostrain. The results provide further evidence that the improved performance of the single channel devices fabricated using a high thermal budget arises from improved surface roughness and reduced Ge diffusion into the Si channel

  14. Meandering River Dynamics: Spatial and Temporal Wave Growth and Non-Periodic Wave Patterns

    Science.gov (United States)

    Weiss, S.; Higdon, J.

    2014-12-01

    The evolution of meandering river channels results from interactions amongst turbulent water flow, sediment transport, and channel geometry. Most current physics-based models derive from the meander-morphodynamics equations introduced by Ikeda et al. (1981). Corresponding linear theories have focused almost exclusively on periodic sequences of small-amplitude meanders. Mathematical consideration of the equations shows that boundary conditions must be chosen carefully to yield numerical solutions for a well posed boundary value problem. The numerical algorithms presented in this work yield 2D solutions to the (corrected) Ikeda et al. (1981) equations with second order convergence in both time and space. We explore the characteristics of spatially versus temporally growing waves, as well as the effects of stochastic variations in the upstream boundary condition and in the dimensionless parameter β, which characterizes the strength of secondary flow relative to cross-stream shear. Consideration of the growth patterns for spatially growing waves provides some insight for the design of experimental systems exhibiting self sustaining river meanders.

  15. A high performance magnetorheological valve with a meandering flow path

    International Nuclear Information System (INIS)

    Imaduddin, Fitrian; Amri Mazlan, Saiful; Azizi Abdul Rahman, Mohd; Zamzuri, Hairi; Ubaidillah; Ichwan, Burhanuddin

    2014-01-01

    The huge developments in the field of magnetorheological (MR) fluid-based devices will have a great influence on the future of mechatronic applications due to the ease of interfacing between electronic controls and the mechanical components that they provide. Among various MR fluid-based devices, an MR valve would be particularly significant for the development of other devices, if it could be successfully achieved. One of the most challenging obstacles to MR valve development is the difficulty of achieving device miniaturization while, at the same time, improving the achievable performance. This study demonstrates a novel design for an MR valve, using the meandering flow path approach in order to increase the effective area so that the MR fluid can be regulated within a small-sized valve. The meandering flow path is formed by combining multiple annular, radial and orifice flow channels. In order to analyze the valve performance, a mathematical model of the proposed MR valve is derived and combined with numerical simulation using the finite element method, with the intention of predicting the achievable pressure drop that can be generated by the valve. The predicted MR valve performances are then experimentally evaluated using an oscillation-disturbed bypass hydraulic cylinder. The simulation results show that the proposed MR valve design could yield substantial pressure drop improvement, which is confirmed by the experiment

  16. Meanders and eddy formation by a buoyant coastal current flowing over a sloping topography

    Directory of Open Access Journals (Sweden)

    L. Cimoli

    2017-11-01

    Full Text Available This study investigates the linear and non-linear instability of a buoyant coastal current flowing along a sloping topography. In fact, the bathymetry strongly impacts the formation of meanders or eddies and leads to different dynamical regimes that can both enhance or prevent the cross-shore transport. We use the Regional Ocean Modeling System (ROMS to run simulations in an idealized channel configuration, using a fixed coastal current structure and testing its unstable evolution for various depths and topographic slopes. The experiments are integrated beyond the linear stage of the instability, since our focus is on the non-linear end state, namely the formation of coastal eddies or meanders, to classify the dynamical regimes. We find three non-linear end states, whose properties cannot be deduced solely from the linear instability analysis. They correspond to a quasi-stable coastal current, the propagation of coastal meanders, and the formation of coherent eddies. We show that the topographic parameter Tp, defined as the ratio of the topographic Rossby wave speed over the current speed, plays a key role in controlling the amplitude of the unstable cross-shore perturbations. This result emphasizes the limitations of linear stability analysis to predict the formation of coastal eddies, because it does not account for the non-linear saturation of the cross-shore perturbations, which is predominant for large negative Tp values. We show that a second dimensionless parameter, the vertical aspect ratio γ, controls the transition from meanders to coherent eddies. We suggest the use of the parameter space (Tp, γ to describe the emergence of coastal eddies or meanders from an unstable buoyant current. By knowing the values of Tp and γ for an observed flow, which can be calculated from hydrological sections, we can identify which non-linear end state characterizes that flow – namely if it is quasi-stable, meanders, or forms eddies.

  17. Two-dimensional probability density analysis of single channel currents from reconstituted acetylcholine receptors and sodium channels.

    Science.gov (United States)

    Keller, B U; Montal, M S; Hartshorne, R P; Montal, M

    1990-01-01

    Two-dimensional probability density analysis of single channel current recordings was applied to two purified channel proteins reconstituted in planar lipid bilayers: Torpedo acetylcholine receptors and voltage-sensitive sodium channels from rat brain. The information contained in the dynamic history of the gating process, i.e., the time sequence of opening and closing events was extracted from two-dimensional distributions of transitions between identifiable states. This approach allows one to identify kinetic models consistent with the observables. Gating of acetylcholine receptors expresses "memory" of the transition history: the receptor has two channel open (O) states; the residence time in each of them strongly depends on both the preceding open time and the intervening closed interval. Correspondingly, the residence time in the closed (C) states depends on both the preceding open time and the preceding closed time. This result confirms the scheme that considers, at least, two transition pathways between the open and closed states and extends the details of the model in that it defines that the short-lived open state is primarily entered from long-lived closed states while the long-lived open state is accessed mainly through short-lived closed states. Since ligand binding to the acetylcholine-binding sites is a reaction with channel closed states, we infer that the longest closed state (approximately 19 ms) is unliganded, the intermediate closed state (approximately 2 ms) is singly liganded and makes transitions to the short open state (approximately 0.5 ms) and the shortest closed state (approximately 0.4 ms) is doubly liganded and isomerizes to long open states (approximately 5 ms). This is the simplest interpretation consistent with available data. In contrast, sodium channels modified with batrachotoxin to eliminate inactivation show no correlation in the sequence of channel opening and closing events, i.e., have no memory of the transition history. This

  18. Generic Single-Channel Detection of Absence Seizures

    DEFF Research Database (Denmark)

    Petersen, Eline B.; Duun-Henriksen, Jonas; Mazzaretto, Andrea

    2011-01-01

    is obtained for the derivation F7-FP1. Using this channel a sensitivity of 99.1 %, positive predictive value of 94.8 %, mean detection latency of 3.7 s, and false detection rate value of 0.5/h was obtained. The topographical visualization of the results clearly shows that the frontal, midline, and parietal...

  19. Three-channel single-wavelength lidar depolarization calibration

    Science.gov (United States)

    McCullough, Emily M.; Sica, Robert J.; Drummond, James R.; Nott, Graeme J.; Perro, Christopher; Duck, Thomas J.

    2018-02-01

    Linear depolarization measurement capabilities were added to the CANDAC Rayleigh-Mie-Raman lidar (CRL) at Eureka, Nunavut, in the Canadian High Arctic in 2010. This upgrade enables measurements of the phases (liquid versus ice) of cold and mixed-phase clouds throughout the year, including during polar night. Depolarization measurements were calibrated according to existing methods using parallel- and perpendicular-polarized profiles as discussed in ). We present a new technique that uses the polarization-independent Rayleigh elastic channel in combination with one of the new polarization-dependent channels, and we show that for a lidar with low signal in one of the polarization-dependent channels this method is superior to the traditional method. The optimal procedure for CRL is to determine the depolarization parameter using the traditional method at low resolution (from parallel and perpendicular signals) and then to use this value to calibrate the high-resolution new measurements (from parallel and polarization-independent Rayleigh elastic signals). Due to its use of two high-signal-rate channels, the new method has lower statistical uncertainty and thus gives depolarization parameter values at higher spatial-temporal resolution by up to a factor of 20 for CRL. This method is easily adaptable to other lidar systems which are considering adding depolarization capability to existing hardware.

  20. Three-channel single-wavelength lidar depolarization calibration

    Directory of Open Access Journals (Sweden)

    E. M. McCullough

    2018-02-01

    Full Text Available Linear depolarization measurement capabilities were added to the CANDAC Rayleigh–Mie–Raman lidar (CRL at Eureka, Nunavut, in the Canadian High Arctic in 2010. This upgrade enables measurements of the phases (liquid versus ice of cold and mixed-phase clouds throughout the year, including during polar night. Depolarization measurements were calibrated according to existing methods using parallel- and perpendicular-polarized profiles as discussed in . We present a new technique that uses the polarization-independent Rayleigh elastic channel in combination with one of the new polarization-dependent channels, and we show that for a lidar with low signal in one of the polarization-dependent channels this method is superior to the traditional method. The optimal procedure for CRL is to determine the depolarization parameter using the traditional method at low resolution (from parallel and perpendicular signals and then to use this value to calibrate the high-resolution new measurements (from parallel and polarization-independent Rayleigh elastic signals. Due to its use of two high-signal-rate channels, the new method has lower statistical uncertainty and thus gives depolarization parameter values at higher spatial–temporal resolution by up to a factor of 20 for CRL. This method is easily adaptable to other lidar systems which are considering adding depolarization capability to existing hardware.

  1. Single sodium channels from human skeletal muscle in planar lipid bilayers: characterization and response to pentobarbital.

    Science.gov (United States)

    Wartenberg, Hans C; Urban, Bernd W

    2004-01-01

    To investigate the response to general anesthetics of different sodium-channel subtypes, we examined the effects of pentobarbital, a close thiopental analogue, on single sodium channels from human skeletal muscle and compared them to existing data from human brain and human ventricular muscle channels. Sodium channels from a preparation of human skeletal muscle were incorporated into planar lipid bilayers, and the steady-state behavior of single sodium channels and their response to pentobarbital was examined in the presence of batrachotoxin, a sodium-channel activator. Single-channel currents were recorded before and after the addition of pentobarbital (0.34-1.34 mM). In symmetrical 500 mM NaCl, human skeletal muscle sodium channels had an averaged single-channel conductance of 21.0 +/- 0.6 pS, and the channel fractional open time was 0.96 +/- 0.04. The activation midpoint potential was -96.2 +/- 1.6 mV. Extracellular tetrodotoxin blocked the channel with a half-maximal concentration (k1/2) of 60 nM at 0 mV. Pentobarbital reduced the time-averaged conductance of single skeletal muscle sodium channels in a concentration-dependent manner (inhibitory concentration 50% [IC50] = 0.66 mM). The steady-state activation was shifted to more hyperpolarized potentials (-16.7 mV at 0.67 mM pentobarbital). In the planar lipid bilayer system, skeletal muscle sodium channels have some electrophysiological properties that are significantly different compared with those of sodium channels from cardiac or from central nervous tissue. In contrast to the control data, these different human sodium channel subtypes showed the same qualitative and quantitative response to the general anesthetic pentobarbital. The implication of these effects for overall anesthesia will depend on the role the individual channels play within their neuronal networks, but suppression of both central nervous system and peripheral sodium channels may add to general anesthetic effects.

  2. Single sodium channels from human skeletal muscle in planar lipid bilayers: characterization and response to pentobarbital

    NARCIS (Netherlands)

    Wartenberg, Hans C.; Urban, Bernd W.

    2004-01-01

    PURPOSE: To investigate the response to general anesthetics of different sodium-channel subtypes, we examined the effects of pentobarbital, a close thiopental analogue, on single sodium channels from human skeletal muscle and compared them to existing data from human brain and human ventricular

  3. Development of NUPREP PC Version and Input Structures for NUCIRC Single Channel Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Churl; Jun, Ji Su; Park, Joo Hwan

    2007-12-15

    The input file for a steady-state thermal-hydraulic code NUCIRC consists of common channel input data and specific channel input data in a case of single channel analysis. Even when all the data is ready for the 380 channels' single channel analyses, it takes long time and requires enormous effort to compose an input file by hand-editing. The automatic pre-processor for this tedious job is a NUPREP code. In this study, a NUPREP PC version has been developed from the source list in the program manual of NUCIRC-MOD2.000 that is imported in a form of an execution file. In this procedure, some errors found in PC executions and lost statements are fixed accordingly. It is confirmed that the developed NUPREP code produces input file correctly for the CANDU-6 single channel analysis. Additionally, the NUCIRC input structure and data format are summarized for a single channel analysis and the input CARDs required for the creep information of aged channels are listed.

  4. Development of NUPREP PC Version and Input Structures for NUCIRC Single Channel Analyses

    International Nuclear Information System (INIS)

    Yoon, Churl; Jun, Ji Su; Park, Joo Hwan

    2007-12-01

    The input file for a steady-state thermal-hydraulic code NUCIRC consists of common channel input data and specific channel input data in a case of single channel analysis. Even when all the data is ready for the 380 channels' single channel analyses, it takes long time and requires enormous effort to compose an input file by hand-editing. The automatic pre-processor for this tedious job is a NUPREP code. In this study, a NUPREP PC version has been developed from the source list in the program manual of NUCIRC-MOD2.000 that is imported in a form of an execution file. In this procedure, some errors found in PC executions and lost statements are fixed accordingly. It is confirmed that the developed NUPREP code produces input file correctly for the CANDU-6 single channel analysis. Additionally, the NUCIRC input structure and data format are summarized for a single channel analysis and the input CARDs required for the creep information of aged channels are listed

  5. Single-Particle Cryo-EM of the Ryanodine Receptor Channel in an Aqueous Environment.

    Science.gov (United States)

    Baker, Mariah R; Fan, Guizhen; Serysheva, Irina I

    2015-01-07

    Ryanodine receptors (RyRs) are tetrameric ligand-gated Ca(2+) release channels that are responsible for the increase of cytosolic Ca(2+) concentration leading to muscle contraction. Our current understanding of RyR channel gating and regulation is greatly limited due to the lack of a high-resolution structure of the channel protein. The enormous size and unwieldy shape of Ca(2+) release channels make X-ray or NMR methods difficult to apply for high-resolution structural analysis of the full-length functional channel. Single-particle electron cryo-microscopy (cryo-EM) is one of the only effective techniques for the study of such a large integral membrane protein and its molecular interactions. Despite recent developments in cryo-EM technologies and break-through single-particle cryo-EM studies of ion channels, cryospecimen preparation, particularly the presence of detergent in the buffer, remains the main impediment to obtaining atomic-resolution structures of ion channels and a multitude of other integral membrane protein complexes. In this review we will discuss properties of several detergents that have been successfully utilized in cryo-EM studies of ion channels and the emergence of the detergent alternative amphipol to stabilize ion channels for structure-function characterization. Future structural studies of challenging specimen like ion channels are likely to be facilitated by cryo-EM amenable detergents or alternative surfactants.

  6. Single channel speech enhancement in the modulation domain: New insights in the modulation channel selection framework

    DEFF Research Database (Denmark)

    Boldt, Jesper B.; Bertelsen, Andreas Thelander; Gran, Fredrik

    2015-01-01

    Recently, the ideal binary mask has been introduced in the modulation domain by extending the ideal channel selection method to modulation channel selection [1]. This new method shows substantial improvement in speech intelligibility but less than its predecessor despite the higher complexity. Here......, we extend the previous finding from [1] and provide a more direct comparison of binary masking in the modulation domain with binary masking in the time-frequency domain. Subjective and objective evaluations are performed and provide additional insight into modulation domain processing....

  7. Sleep Apnoea Detection in Single Channel ECGs by Analyzing Heart Rate Dynamics

    National Research Council Canada - National Science Library

    Zywietz, C

    2001-01-01

    .... Sleep disorders are typically investigated by means of polysomnographic recordings. We have analyzed 70 eight-hour single-channel ECG recordings to find out to which extent sleep apneas may be detected from the ECG alone...

  8. An approach to emotion recognition in single-channel EEG signals: a mother child interaction

    Science.gov (United States)

    Gómez, A.; Quintero, L.; López, N.; Castro, J.

    2016-04-01

    In this work, we perform a first approach to emotion recognition from EEG single channel signals extracted in four (4) mother-child dyads experiment in developmental psychology. Single channel EEG signals are analyzed and processed using several window sizes by performing a statistical analysis over features in the time and frequency domains. Finally, a neural network obtained an average accuracy rate of 99% of classification in two emotional states such as happiness and sadness.

  9. Examining the physical meaning of the bank erosion coefficient used in meander migration modeling

    Science.gov (United States)

    Constantine, Candice R.; Dunne, Thomas; Hanson, Gregory J.

    2009-05-01

    Widely used models of meander evolution relate migration rate to vertically averaged near-bank velocity through the use of a coefficient of bank erosion ( E). In applications to floodplain management problems, E is typically determined through calibration to historical planform changes, and thus its physical meaning remains unclear. This study attempts to clarify the extent to which E depends on measurable physical characteristics of the channel boundary materials using data from the Sacramento River, California, USA. Bend-average values of E were calculated from measured long-term migration rates and computed near-bank velocities. In the field, unvegetated bank material resistance to fluvial shear ( k) was measured for four cohesive and noncohesive bank types using a jet-test device. At a small set of bends for which both E and k were obtained, we discovered that variability in k explains much of the variability in E. The form of this relationship suggests that when modeling long-term meander migration of large rivers, E depends largely on bank material properties. This finding opens up the possibility that E may be estimated directly from field data, enabling prediction of meander migration rates for systems where historical data are unavailable or controlling conditions have changed. Another implication is that vegetation plays a limited role in affecting long-term meander migration rates of large rivers like the Sacramento River. These hypotheses require further testing with data sets from other large rivers.

  10. 4 × 160-Gbit/s multi-channel regeneration in a single fiber

    DEFF Research Database (Denmark)

    Wang, Ju; Ji, Hua; Hu, Hao

    2014-01-01

    Simultaneous regeneration of four high-speed (160 Gbit/s) wavelength-division multiplexed (WDM) and polarization-division multiplexed (PDM) signals in a single highly nonlinear fiber (HNLF) is demonstrated. The regeneration operation is based on four-wave mixing in HNLF, where the degraded data...... phase modulation of the CW light. Mitigation of the inter-channel nonlinearities is achieved mainly through an inter-channel 0.5 bit slot time delay. Bidirectional propagation is also applied to relieve the inter-channel four-wave mixing. The multi-channel regeneration performance is validated by bit...

  11. Changes in ion channel geometry resolved to sub-angstroem precision via single molecule mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, Joseph W F; Kasianowicz, John J; Reiner, Joseph E [Semiconductor Electronics Division, Electronics and Electrical Engineering Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States)

    2010-11-17

    The ion channel formed by Staphylococcus aureus alpha-hemolysin switches between multiple open conducting states. We describe a method for precisely estimating the changes in the ion channel geometry that correspond to these different states. Experimentally, we observed that the permeability of a single channel to differently sized poly(ethylene glycol) molecules depends on the magnitude of the open state conductance. A simple theory is proposed for determining changes in channel length of 4.2% and in cross-sectional area of - 0.4%.

  12. Multi-Channel Distributed Coordinated Function over Single Radio in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Kok-Keong (Jonathan Loo

    2011-01-01

    Full Text Available Multi-channel assignments are becoming the solution of choice to improve performance in single radio for wireless networks. Multi-channel allows wireless networks to assign different channels to different nodes in real-time transmission. In this paper, we propose a new approach, Multi-channel Distributed Coordinated Function (MC-DCF which takes advantage of multi-channel assignment. The backoff algorithm of the IEEE 802.11 distributed coordination function (DCF was modified to invoke channel switching, based on threshold criteria in order to improve the overall throughput for wireless sensor networks (WSNs over 802.11 networks. We presented simulation experiments in order to investigate the characteristics of multi-channel communication in wireless sensor networks using an NS2 platform. Nodes only use a single radio and perform channel switching only after specified threshold is reached. Single radio can only work on one channel at any given time. All nodes initiate constant bit rate streams towards the receiving nodes. In this work, we studied the impact of non-overlapping channels in the 2.4 frequency band on: constant bit rate (CBR streams, node density, source nodes sending data directly to sink and signal strength by varying distances between the sensor nodes and operating frequencies of the radios with different data rates. We showed that multi-channel enhancement using our proposed algorithm provides significant improvement in terms of throughput, packet delivery ratio and delay. This technique can be considered for WSNs future use in 802.11 networks especially when the IEEE 802.11n becomes popular thereby may prevent the 802.15.4 network from operating effectively in the 2.4 GHz frequency band.

  13. Multi-channel distributed coordinated function over single radio in wireless sensor networks.

    Science.gov (United States)

    Campbell, Carlene E-A; Loo, Kok-Keong Jonathan; Gemikonakli, Orhan; Khan, Shafiullah; Singh, Dhananjay

    2011-01-01

    Multi-channel assignments are becoming the solution of choice to improve performance in single radio for wireless networks. Multi-channel allows wireless networks to assign different channels to different nodes in real-time transmission. In this paper, we propose a new approach, Multi-channel Distributed Coordinated Function (MC-DCF) which takes advantage of multi-channel assignment. The backoff algorithm of the IEEE 802.11 distributed coordination function (DCF) was modified to invoke channel switching, based on threshold criteria in order to improve the overall throughput for wireless sensor networks (WSNs) over 802.11 networks. We presented simulation experiments in order to investigate the characteristics of multi-channel communication in wireless sensor networks using an NS2 platform. Nodes only use a single radio and perform channel switching only after specified threshold is reached. Single radio can only work on one channel at any given time. All nodes initiate constant bit rate streams towards the receiving nodes. In this work, we studied the impact of non-overlapping channels in the 2.4 frequency band on: constant bit rate (CBR) streams, node density, source nodes sending data directly to sink and signal strength by varying distances between the sensor nodes and operating frequencies of the radios with different data rates. We showed that multi-channel enhancement using our proposed algorithm provides significant improvement in terms of throughput, packet delivery ratio and delay. This technique can be considered for WSNs future use in 802.11 networks especially when the IEEE 802.11n becomes popular thereby may prevent the 802.15.4 network from operating effectively in the 2.4 GHz frequency band.

  14. A meander-scale field investigation of linkages between fluvial geomorphology and patterns in hyporheic exchange

    Science.gov (United States)

    Malenda, H. F.; Guryan, G.; Stauffer, S. J.; Rowland, J. C.; Singha, K.

    2016-12-01

    Although physically based numerical models suggest that lateral hyporheic exchange is greatly affected by channel and floodplain geomorphology, many models regularly simplify fluvial conditions, including flood plain sedimentology. Simplifications are rooted in a paucity of available hydrogeomorphic data and of field observations at scales large enough to capture effects of buried intra-meander geomorphic structures, such as former channels or point bars, on hyporheic exchange. To better represent fluvial geomorphology in hyporheic models, we explore how the interaction between hydraulic geometry and floodplain sedimentology affects preferential flow paths of hyporheic water. The study site includes a 150-m long, sinuous reach of the East River, near Crested Butte, Colorado. Subsurface intra-meander geomorphic structures, such as buried alternate bars and channels are identified using ground-penetrating radar (GPR) and are corroborated by point sediment descriptions collected during piezometer installment. The hydraulic geometry of the river is constructed by field measurements of stream bathymetry, discharge, and slope. Hyporheic residence times and flow paths are measured using Rhodamine Water Tracer (RWT) tests, and breakthrough curves are constructed in-stream as well as intra-meander by sampling an established piezometer network. This combined approach allows for the identification of major controls that subsurface deposits may exert on hyporheic exchange and more efficient integration of subsurface heterogeneities in hyporheic models.

  15. The nematocyst extract of Hydra attenuata causes single channel events in lipid bilayers.

    Science.gov (United States)

    Weber, J; Schürholz, T; Neumann, E

    1990-01-01

    The nematocyst extract of Hydra attenuata causes single conductance events in reconstituted planar lipid membranes as well as in inside-out patches derived from liposomes. The smallest single channel conductance level of the toxins is 110 pS. The conductance levels increase stepwise with time up to 2000 pS. These large conductance jumps indicate channel cooperativity. If the membrane-voltage is changed from positive to negative values, the single channel events become undefined and noisy, indicating major reorganizations of the proteins which form the channels. The molecular properties of the ionophoric component(s) of the nematocyst extract may help explain the observed macroscopic effects, such as hemolysis of human erythrocytes, after addition of the nematocyst extract.

  16. Effect of Channel Bends on Transverse Mixing | Engmann | Nigerian ...

    African Journals Online (AJOL)

    Velocity and tracer concentration measurements made in a meandering channel are used to discuss the effect of bends on the transverse mixing of a conservative tracer introduced into the flow. It is shown that bend induced spiral motion greatly enhance the mixing potential of meandering channel flows; The magnitude of ...

  17. Insulin activates single amiloride-blockable Na channels in a distal nephron cell line (A6).

    Science.gov (United States)

    Marunaka, Y; Hagiwara, N; Tohda, H

    1992-09-01

    Using the patch-clamp technique, we studied the effect of insulin on an amiloride-blockable Na channel in the apical membrane of a distal nephron cell line (A6) cultured on permeable collagen films for 10-14 days. NPo (N, number of channels per patch membrane; Po, average value of open probability of individual channels in the patch) under baseline conditions was 0.88 +/- 0.12 (SE)(n = 17). After making cell-attached patches on the apical membrane which contained Na channels, insulin (1 mU/ml) was applied to the serosal bath. While maintaining the cell-attached patch, NPo significantly increased to 1.48 +/- 0.19 (n = 17; P less than 0.001) after 5-10 min of insulin application. The open probability of Na channels was 0.39 +/- 0.01 (n = 38) under baseline condition, and increased to 0.66 +/- 0.03 (n = 38, P less than 0.001) after addition of insulin. The baseline single-channel conductance was 4pS, and neither the single-channel conductance nor the current-voltage relationship was significantly changed by insulin. These results indicate that insulin increases Na absorption in the distal nephron by increasing the open probability of the amiloride-blockable Na channel.

  18. Safety of multi-channel stimulation implants: a single blocking capacitor per channel is not sufficient after single-fault failure.

    Science.gov (United States)

    Nonclercq, Antoine; Lonys, Laurent; Vanhoestenberghe, Anne; Demosthenous, Andreas; Donaldson, Nick

    2012-04-01

    One reason given for placing capacitors in series with stimulation electrodes is that they prevent direct current flow and therefore tissue damage under fault conditions. We show that this is not true for multiplexed multi-channel stimulators with one capacitor per channel. A test bench of two stimulation channels, two stimulation tripoles and a saline bath was used to measure the direct current flowing through the electrodes under two different single fault conditions. The electrodes were passively discharged between stimulation pulses. For the particular condition used (16 mA, 1 ms stimulation pulse at 20 Hz with electrodes placed 5 cm apart), the current ranged from 38 to 326 μA depending on the type of fault. The variation of the fault current with time, stimulation amplitude, stimulation frequency and distance between the electrodes is given. Possible additional methods to improve safety are discussed.

  19. Coulomb blockade in a Si channel gated by an Al single-electron transistor

    OpenAIRE

    Sun, L.; Brown, K. R.; Kane, B. E.

    2007-01-01

    We incorporate an Al-AlO_x-Al single-electron transistor as the gate of a narrow (~100 nm) metal-oxide-semiconductor field-effect transistor (MOSFET). Near the MOSFET channel conductance threshold, we observe oscillations in the conductance associated with Coulomb blockade in the channel, revealing the formation of a Si single-electron transistor. Abrupt steps present in sweeps of the Al transistor conductance versus gate voltage are correlated with single-electron charging events in the Si t...

  20. 0.4 THz Photonic-Wireless Link With 106 Gb/s Single Channel Bitrate

    DEFF Research Database (Denmark)

    Jia, Shi; Pang, Xiaodan; Ozolins, Oskars

    2018-01-01

    THz channel is enabled by combining spectrally efficient modulation format, ultrabroadband THz transceiver and advanced digital signal processing routine. Besides that, our demonstration from system-wide implementation viewpoint also features high transmission stability, and hence shows its great......, we experimentally demonstrate a single channel 0.4 THz photonic-wireless link achieving a net data rate of beyond 100 Gb/s by using a single pair of THz emitter and receiver, without employing any spatial/frequency division multiplexing techniques. The high throughput up to 106 Gb/s within a single...

  1. Three-Dimensional Imaging by Self-Reference Single-Channel Digital Incoherent Holography.

    Science.gov (United States)

    Rosen, Joseph; Kelner, Roy

    2016-08-01

    Digital holography offers a reliable and fast method to image a three-dimensional scene from a single perspective. This article reviews recent developments of self-reference single-channel incoherent hologram recorders. Hologram recorders in which both interfering beams, commonly referred to as the signal and the reference beams, originate from the same observed objects are considered as self-reference systems. Moreover, the hologram recorders reviewed herein are configured in a setup of a single channel interferometer. This unique configuration is achieved through the use of one or more spatial light modulators.

  2. Three-Dimensional Imaging by Self-Reference Single-Channel Digital Incoherent Holography

    Science.gov (United States)

    Rosen, Joseph; Kelner, Roy

    2016-01-01

    Digital holography offers a reliable and fast method to image a three-dimensional scene from a single perspective. This article reviews recent developments of self-reference single-channel incoherent hologram recorders. Hologram recorders in which both interfering beams, commonly referred to as the signal and the reference beams, originate from the same observed objects are considered as self-reference systems. Moreover, the hologram recorders reviewed herein are configured in a setup of a single channel interferometer. This unique configuration is achieved through the use of one or more spatial light modulators. PMID:28757811

  3. The effects of floodplain soil heterogeneity on meander planform shape

    Science.gov (United States)

    Motta, D.; Abad, J. D.; Langendoen, E. J.; GarcíA, M. H.

    2012-09-01

    Past analytical studies of meander planform development have mostly focused on the complexity of the governing equations, i.e., hydrodynamics, and less so on the stream bank resistance to erosion, whose spatial heterogeneity is difficult to describe deterministically. This motivated the use of a Monte Carlo approach to examine the effects of floodplain soils and their distribution on planform development, with the goal of including bank erosion properties in the analysis. Simulated bank erosion rates are controlled by the resistance to hydraulic erosion of the bank soils using an excess shear stress approach. The spatial distribution of critical shear stress across the floodplain is delineated on a rectangular, equidistant grid with varying degrees of variability. The corresponding erodibility coefficient is computed using a field-derived empirical relation. For a randomly disturbed distribution, in which the mean resistance to erosion exponentially increases away from the valley centerline, two relevant parameters are identified: the standard deviation of the critical shear stress distribution, which controls skewness and variability of the channel centerline, and the cross-valley increase in soil resistance, which constrains lateral migration and also affects bend skewness. For a purely random distribution, migrated centerlines exhibit larger variability for increasing spatial scales of floodplain soil heterogeneity. For equal stochastic variability of the corresponding governing parameters, relating meander migration to hydraulic erosion of the bank soils produces more variability and shape complexity than the "classic" bank migration approach of Ikeda et al. (1981), which relates migration rate to excess velocity at the outer bank. Finally, the proposed stochastic approach provides a foundation for estimating a suitable spatial density of measurements to characterize the physical properties of floodplain soils and vegetation.

  4. Single top quarks at the Tevatron and observation of the s-channel production mode

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    The presentation gives an overview of single-top-quark production at the Tevatron proton-antiproton collider. The talk covers measurements of the total s+t channel production cross section and the extraction of the CKM matrix element |V_tb|. Furthermore, separate analyses of the s-channel and t-channel production modes are discussed. The data correspond to total integrated luminosities of up to 9.7 fb-1 per experiment and represent in most cases the full Run-II dataset. Through a combination of the CDF and D0 measurements the first observation of single-top-quark production in the s-channel is claimed. This is particularly highlighted in the seminar.

  5. Effects of the physiological parameters on the signal-to-noise ratio of single myoelectric channel

    Directory of Open Access Journals (Sweden)

    Zhang YT

    2007-08-01

    Full Text Available Abstract Background An important measure of the performance of a myoelectric (ME control system for powered artificial limbs is the signal-to-noise ratio (SNR at the output of ME channel. However, few studies illustrated the neuron-muscular interactive effects on the SNR at ME control channel output. In order to obtain a comprehensive understanding on the relationship between the physiology of individual motor unit and the ME control performance, this study investigates the effects of physiological factors on the SNR of single ME channel by an analytical and simulation approach, where the SNR is defined as the ratio of the mean squared value estimation at the channel output and the variance of the estimation. Methods Mathematical models are formulated based on three fundamental elements: a motoneuron firing mechanism, motor unit action potential (MUAP module, and signal processor. Myoelectric signals of a motor unit are synthesized with different physiological parameters, and the corresponding SNR of single ME channel is numerically calculated. Effects of physiological multi factors on the SNR are investigated, including properties of the motoneuron, MUAP waveform, recruitment order, and firing pattern, etc. Results The results of the mathematical model, supported by simulation, indicate that the SNR of a single ME channel is associated with the voluntary contraction level. We showed that a model-based approach can provide insight into the key factors and bioprocess in ME control. The results of this modelling work can be potentially used in the improvement of ME control performance and for the training of amputees with powered prostheses. Conclusion The SNR of single ME channel is a force, neuronal and muscular property dependent parameter. The theoretical model provides possible guidance to enhance the SNR of ME channel by controlling physiological variables or conscious contraction level.

  6. 70 GeV proton volume capture into channeling mode with a bent Si single crystal

    International Nuclear Information System (INIS)

    Chesnokov, Yu.A.; Galyaev, N.A.; Kotov, V.I.; Tsarik, S.V.; Zapol'skij, V.N.

    1990-01-01

    The existence of the volume capture of 70 GeV protons with a Si bent single crystal of (111) orientation into the channeling mode gas experimentally been proved. The data on the probability of capturing protons into the channeling mode versus the bending radius of the crystal have been obtained together with the information on the dynamics of volume captured particle dechanneling. 10 refs

  7. Dynamic Phenylalanine Clamp Interactions Define Single-Channel Polypeptide Translocation through the Anthrax Toxin Protective Antigen Channel.

    Science.gov (United States)

    Ghosal, Koyel; Colby, Jennifer M; Das, Debasis; Joy, Stephen T; Arora, Paramjit S; Krantz, Bryan A

    2017-03-24

    Anthrax toxin is an intracellularly acting toxin where sufficient detail is known about the structure of its channel, allowing for molecular investigations of translocation. The toxin is composed of three proteins, protective antigen (PA), lethal factor (LF), and edema factor (EF). The toxin's translocon, PA, translocates the large enzymes, LF and EF, across the endosomal membrane into the host cell's cytosol. Polypeptide clamps located throughout the PA channel catalyze the translocation of LF and EF. Here, we show that the central peptide clamp, the ϕ clamp, is a dynamic site that governs the overall peptide translocation pathway. Single-channel translocations of a 10-residue, guest-host peptide revealed that there were four states when peptide interacted with the channel. Two of the states had intermediate conductances of 10% and 50% of full conductance. With aromatic guest-host peptides, the 50% conducting intermediate oscillated with the fully blocked state. A Trp guest-host peptide was studied by manipulating its stereochemistry and prenucleating helix formation with a covalent linkage in the place of a hydrogen bond or hydrogen-bond surrogate (HBS). The Trp peptide synthesized with ʟ-amino acids translocated more efficiently than peptides synthesized with D- or alternating D,ʟ-amino acids. HBS stapled Trp peptide exhibited signs of steric hindrance and difficulty translocating. However, when mutant ϕ clamp (F427A) channels were tested, the HBS peptide translocated normally. Overall, peptide translocation is defined by dynamic interactions between the peptide and ϕ clamp. These dynamics require conformational flexibility, such that the peptide productively forms both extended-chain and helical states during translocation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Linear program differentiation for single-channel speech separation

    DEFF Research Database (Denmark)

    Pearlmutter, Barak A.; Olsson, Rasmus Kongsgaard

    2006-01-01

    Many apparently difficult problems can be solved by reduction to linear programming. Such problems are often subproblems within larger systems. When gradient optimisation of the entire larger system is desired, it is necessary to propagate gradients through the internally-invoked LP solver....... For instance, when an intermediate quantity z is the solution to a linear program involving constraint matrix A, a vector of sensitivities dE/dz will induce sensitivities dE/dA. Here we show how these can be efficiently calculated, when they exist. This allows algorithmic differentiation to be applied...... to algorithms that invoke linear programming solvers as subroutines, as is common when using sparse representations in signal processing. Here we apply it to gradient optimisation of over complete dictionaries for maximally sparse representations of a speech corpus. The dictionaries are employed in a single...

  9. Thermal-Hydraulics analysis of pressurized water reactor core by using single heated channel model

    Directory of Open Access Journals (Sweden)

    Reza Akbari

    2017-08-01

    Full Text Available Thermal hydraulics of nuclear reactor as a basis of reactor safety has a very important role in reactor design and control. The thermal-hydraulic analysis provides input data to the reactor-physics analysis, whereas the latter gives information about the distribution of heat sources, which is needed to perform the thermal-hydraulic analysis. In this study single heated channel model as a very fast model for predicting thermal hydraulics behavior of pressurized water reactor core has been developed. For verifying the results of this model, we used RELAP5 code as US nuclear regulatory approved thermal hydraulics code. The results of developed single heated channel model have been checked with RELAP5 results for WWER-1000. This comparison shows the capability of single heated channel model for predicting thermal hydraulics behavior of reactor core.

  10. Single top measurements at the LHC: $s$-channel and $Wt$ production

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00214457; The ATLAS collaboration

    2016-01-01

    This paper summarises the latest experimental results on single top quark physics by the ATLAS and CMS collaborations using LHC proton--proton collisions at $\\sqrt{s}=8 \\rm \\ TeV$. Searches for single top-quark production in the $s$-channel and associated $Wt$ mode are presented and a determination of the CKM matrix element $|V_{tb}|$ is discussed. Evidence for $s$-channel production is reported by the ATLAS collaboration and the $Wt$ process has been observed at the LHC.

  11. 16 channel WDM regeneration in a single phase-sensitive amplifier through optical Fourier transformation

    DEFF Research Database (Denmark)

    Guan, Pengyu; Da Ros, Francesco; Lillieholm, Mads

    2016-01-01

    We demonstrate simultaneous phase regeneration of 16-WDM DPSK channels using optical Fourier transformation and a single phase-sensitive amplifier. The BERs of 16-WDM×10-Gbit/s phase noise degraded DPSK signals are improved by 0.4-1.3 orders of magnitude......We demonstrate simultaneous phase regeneration of 16-WDM DPSK channels using optical Fourier transformation and a single phase-sensitive amplifier. The BERs of 16-WDM×10-Gbit/s phase noise degraded DPSK signals are improved by 0.4-1.3 orders of magnitude...

  12. Meandering down to the Sea: The Wandering Ways of Rivers.

    Science.gov (United States)

    Aslamazov, Lev

    1992-01-01

    Discusses the hydrodynamic reasons why a riverbed meanders through a plain. Describes how water movement at a bend in a river causes erosion and changes in the riverbed. Provides a mathematical model to explain the periodic shape of meanders of a river in a plain. (MDH)

  13. On atmospheric stability in the dynamic wake meandering model

    DEFF Research Database (Denmark)

    Keck, Rolf-Erik; de Mare, Martin Tobias; Churchfield, Matthew J.

    2014-01-01

    The present study investigates a new approach for capturing the effects of atmospheric stability on wind turbine wake evolution and wake meandering by using the dynamic wake meandering model. The most notable impact of atmospheric stability on the wind is the changes in length and velocity scales...... spectra and applied to the dynamic wake meandering model to capture the correct wake meandering behaviour. The ambient turbulence in all stability classes is generated using the Mann turbulence model, where the effects of non-neutral atmospheric stability are approximated by the selection of input...... in the computational domain. The changes in the turbulent length scales due to the various atmospheric stability states impact the wake meandering characteristics and thus the power generation by the individual turbines. The proposed method is compared with results from both large-eddy simulation coupled...

  14. Even distribution/dividing of single-phase fluids by symmetric bifurcation of flow channels

    International Nuclear Information System (INIS)

    Liu, Hong; Li, Peiwen

    2013-01-01

    Highlights: ► We addressed an issue of distributing a flow to a number of flow channels uniformly. ► The flow distribution is accomplished through bifurcation of channels. ► Some key parameters to the flow distribution uniformity have been identified. ► Flow uniformity was studied for several versions of flow distributor designs. ► A novel fluid packaging device of high efficiency was provided. -- Abstract: This study addresses a fundamental issue of distributing a single-phase fluid flow into a number of flow channels uniformly. A basic mechanism of flow distribution is accomplished through bifurcation of channels that symmetrically split one flow channel into two downstream channels. Applying the basic mechanism, cascades flow distributions are designed to split one flow into a large number of downstream flows uniformly. Some key parameters decisive to the flow distribution uniformity in such a system have been identified, and the flow distribution uniformity of air was studied for several versions of flow distributor designs using CFD analysis. The effect of the key parameters of the flow channel designs to the flow distribution uniformity was investigated. As an example of industrial application, a novel fluid packaging device of high efficiency was proposed and some CFD analysis results for the device were provided. The optimized flow distributor makes a very good uniform flow distribution which will significantly improve the efficiency of fluid packaging. The technology is expected to be of great significance to many industrial devices that require high uniformity of flow distribution

  15. Ion mass dependence for low energy channeling in single-wall nanotubes

    International Nuclear Information System (INIS)

    An Monte Carlo (MC) simulation program has been used to study ion mass dependence for the low energy channeling of natural- and pseudo-Ar ions in single-wall nanotubes. The MC simulations show that the channeling critical angle Ψ C obeys the (E) -1/2 and the (M 1 ) -1/2 rules, where E is the incident energy and M 1 is the ion mass. The reason for this may be that the motion of the channeled (or de-channeled) ions should be correlated with both the incident energy E and the incident momentum (2M 1 E) 1/2 , in order to obey the conservation of energy and momentum

  16. 2D numerical modelling of meandering channel formation

    Indian Academy of Sciences (India)

    The sediment transport submodel takes into account the influence of non-uniform sediment with bed surface armoring and considers the impact of secondary flow in ... Engineering Research Center, Chongqing Jiaotong University, Chongqing, China; Chinese Research Academy of Environmental Sciences, Beijing, China ...

  17. Quaternary ammonium compounds as structural probes of single batrachotoxin-activated Na+ channels

    Science.gov (United States)

    1991-01-01

    Quaternary ammonium (QA) blockers are well-known structural probes for studying the permeation pathway of voltage-gated K+ channels. In this study we have examined the effects of a series of n-alkyl- trimethylammonium compounds (Cn-QA) on batrachotoxin (BTX)-activated Na+ channels from skeletal muscle incorporated into planar lipid bilayers. We found that these amphipathic QA compounds (Cn-QA where n = 10-18) block single Na+ channels preferentially from the internal side with equilibrium dissociation constants (KD) in the submicromolar to micromolar range. External application of amphipathic QA compounds is far less effective, by a factor of greater than 200. The block can be described by a QA molecule binding to a single site in the Na+ channel permeation pathway. QA binding affinity is dependent on transmembrane voltage with an effective valence (delta) of approximately 0.5. QA dwell times (given as mean closed times, tau c) increase as a function of n-alkyl chain length, ranging from approximately 13 ms for C10-QA to 500 ms for C18-QA at +50 mV. The results imply that there is a large hydrophobic region within the Na+ channel pore which accepts up to 18 methylene groups of the Cn-QA cation. This hydrophobic domain may be of clinical significance since it also interacts with local anesthetics such as cocaine and mepivacaine. Finally, like BTX-activated Na+ channels in bilayers, unmodified Na+ channels in GH3 cells are also susceptible to QA block. Amphipathic QA cations elicit both tonic and use-dependent inhibitions of normal Na+ currents in a manner similar to that of local anesthetic cocaine. We conclude that amphipathic QA compounds are valuable structural probes to study the permeation pathway of both normal and BTX-activated Na+ channels. PMID:1662681

  18. Tunable single-photon multi-channel quantum router based on an optomechanical system

    Science.gov (United States)

    Ma, Peng-Cheng; Yan, Lei-Lei; Zhang, Jian; Chen, Gui-Bin; Li, Xiao-Wei; Zhan, You-Bang

    2018-01-01

    Routing of photons plays a key role in optical communication networks and quantum networks. Although the quantum routing of signals has been investigated for various systems, both in theory and experiment, the general form of a quantum router with multi-output terminals still needs to be explored. Here, we propose an experimentally accessible tunable single-photon multi-channel routing scheme using an optomechanics cavity which is Coulomb coupled to a nanomechanical resonator. The router can extract single photons from the coherent input signal and directly modulate them into three different output channels. More importantly, the two output signal frequencies can be selected by adjusting the Coulomb coupling strength. For application purposes, we justify that there is insignificant influence from the vacuum and thermal noises on the performance of the router under cryogenic conditions. Our proposal may pave a new avenue towards multi-channel routers and quantum networks.

  19. A compact metamaterial structure with dual-planar meander line (DML) patterns

    Science.gov (United States)

    Xu, Xiaofei; Wang, Yefang; Wei, Juzheng

    2018-03-01

    A compact metamaterial element structure is proposed which is characterized with dual-planar meander line (DML) patterns. Compared with existing single planar solutions, the new design is with an extremely reduced resonance frequency. Good agreement is observed between the simulated and measured results. To strengthen the compacting effect, the effective material properties are further retrieved and compared. By calculating the ratio of resonator size to resonating wavelength, the proposed DML design is featured with a deep subwavelength element size at the order of 1/30 wavelength. We remark that this compacting effect does not sacrifice the functional bandwidth of negative permittivity. The negative permittivity bandwidth for the DML design is nearly 70%, much larger than those of existing single planar structures. By utilizing more advanced fabrication technology, the DML element size can be further decreased if the meander lines are made thinner in future.

  20. Single intravenous and oral dose pharmacokinetics of florfenicol in the channel catfish Ictalurus punctatus

    Science.gov (United States)

    Plasma distribution and elimination of florfenicol in channel catfish were investigated after a single dose (10mg/kg) of intravenous i.v.) or oral administration in freshwater at a mean water temperature of 25.4°C. Florfenicol concentrations in plasma were analyzed by means of liquid chromatography...

  1. Optimization of pumping schemes for 160-Gb/s single channel Raman amplified systems

    DEFF Research Database (Denmark)

    Xu, Lin; Rottwitt, Karsten; Peucheret, Christophe

    2004-01-01

    Three different distributed Raman amplification schemes-backward pumping, bidirectional pumping, and second-order pumping-are evaluated numerically for 160-Gb/s single-channel transmission. The same longest transmission distance of 2500 km is achieved for all three pumping methods with a 105-km...

  2. Automatic detection and classification of artifacts in single-channel EEG

    DEFF Research Database (Denmark)

    Olund, Thomas; Duun-Henriksen, Jonas; Kjaer, Troels W.

    2014-01-01

    artifact classes using the selected features. Single-channel (Fp1-F7) EEG recordings are obtained from experiments with 12 healthy subjects performing artifact inducing movements. The dataset was used to construct and validate the model. Both subject-specific and generic implementation, are investigated...

  3. High-speed indoor optical wireless communication system with single channel imaging receiver.

    Science.gov (United States)

    Wang, Ke; Nirmalathas, Ampalavanapillai; Lim, Christina; Skafidas, Efstratios

    2012-04-09

    In this paper we experimentally investigate a gigabit indoor optical wireless communication system with single channel imaging receiver. It is shown that the use of single channel imaging receiver rejects most of the background light. This single channel imaging receiver is composed of an imaging lens and a small photo-sensitive area photodiode attached on a 2-axis actuator. The actuator and photodiode are placed on the focal plane of the lens to search for the focused light spot. The actuator is voice-coil based and it is low cost and commercially available. With this single channel imaging receiver, bit rate as high as 12.5 Gbps has been successfully demonstrated and the maximum error-free (BER20% has been achieved. When this system is integrated with our recently proposed optical wireless based indoor localization system, both high speed wireless communication and mobility can be provided to users over the entire room. Furthermore, theoretical analysis has been carried out and the simulation results agree well with the experiments. In addition, since the rough location information of the user is available in our proposed system, instead of searching for the focused light spot over a large area on the focal plane of the lens, only a small possible area needs to be scanned. By further pre-setting a proper comparison threshold when searching for the focused light spot, the time needed for searching can be further reduced.

  4. Minimum Symbol Error Rate Detection in Single-Input Multiple-Output Channels with Markov Noise

    DEFF Research Database (Denmark)

    Christensen, Lars P.B.

    2005-01-01

    Minimum symbol error rate detection in Single-Input Multiple- Output(SIMO) channels with Markov noise is presented. The special case of zero-mean Gauss-Markov noise is examined closer as it only requires knowledge of the second-order moments. In this special case, it is shown that optimal detection...

  5. Transmission of Single-Channel 16-QAM Data Signals at Terabaud Symbol Rates

    DEFF Research Database (Denmark)

    Richter, Thomas; Palushani, Evarist; Schmidt-Langhorst, Carsten

    2012-01-01

    We present latest results for OTDM transmission systems in combination with digital coherent detection achieving record-high serial data rates in a single-wavelength channel. We show serial data transmission of 5.1 Tb/s (640 GBd) over 80-km and 10.2 Tb/s (1.28 TBd) over 29-km dispersion managed f...

  6. Single-channel source separation using non-negative matrix factorization

    DEFF Research Database (Denmark)

    Schmidt, Mikkel Nørgaard

    , in which a number of methods for single-channel source separation based on non-negative matrix factorization are presented. In the papers, the methods are applied to separating audio signals such as speech and musical instruments and separating different types of tissue in chemical shift imaging....

  7. An accurate mobility model for the I-V characteristics of n-channel enhancement-mode MOSFETs with single-channel boron implantation

    International Nuclear Information System (INIS)

    Chingyuan Wu; Yeongwen Daih

    1985-01-01

    In this paper an analytical mobility model is developed for the I-V characteristics of n-channel enhancement-mode MOSFETs, in which the effects of the two-dimensional electric fields in the surface inversion channel and the parasitic resistances due to contact and interconnection are included. Most importantly, the developed mobility model easily takes the device structure and process into consideration. In order to demonstrate the capabilities of the developed model, the structure- and process-oriented parameters in the present mobility model are calculated explicitly for an n-channel enhancement-mode MOSFET with single-channel boron implantation. Moreover, n-channel MOSFETs with different channel lengths fabricated in a production line by using a set of test keys have been characterized and the measured mobilities have been compared to the model. Excellent agreement has been obtained for all ranges of the fabricated channel lengths, which strongly support the accuracy of the model. (author)

  8. Rapid replacement of riparian rainforest habitat and the impacts on the meandering dynamics of the Kinabatangan River, Borneo

    Science.gov (United States)

    Horton, Alexander J.; Constantine, José A.

    2014-05-01

    Meandering rivers are defined by their nature to migrate, remobilising floodplain sediment and constructing new surfaces for riparian vegetation to colonise. The presence of riparian vegetation has long been known to limit the ability of rivers to erode riverbanks, but it has remained unclear the principal means by which vegetation provides this function. As a result, most models that predict meandering behaviour do not fully incorporate vegetation, thereby limiting their utility where forest is rapidly replaced. The problem is particularly acute along the Kinabatangan River of Sabah in Malaysian Borneo, where oil palm plantations are replacing one of the oldest riparian rainforests on the planet. The area of Sabah has seen rapid and extensive land use change in the last 40 years, as virgin rainforest has been systematically cleared for logging, and to make way for oil palm plantations. In the 18 years from 1990 to 2008, Sabah lost half of its intact rainforest, which equates to more than 1.85 million hectares. Using Landsat imagery dating back to 1973, we report here the impacts of this rapid land-use change on rates of meander migration on a 280-km reach of the Kinabatangan River. The river planform has been remarkably stable throughout the time period of study, but individual meanders show a rapid response to large discharge events, migrating over an order of magnitude faster than nearby reaches. Rapidly migrating meanders generally occur along portions of floodplain that have been artificially cleared of riparian vegetation, potentially resulting in significant increases in sediment load and within-channel bar development. A field campaign is planned to investigate the mechanisms by which riparian vegetation effect meander migration in these tropical regions.

  9. Testing the role of meander cutoff in promoting gene flow across a riverine barrier in ground skinks (Scincella lateralis.

    Directory of Open Access Journals (Sweden)

    Nathan D Jackson

    Full Text Available Despite considerable attention, the long-term impact of rivers on species diversification remains uncertain. Meander loop cutoff (MLC is one river phenomenon that may compromise a river's diversifying effects by passively transferring organisms from one side of the river to the other. However, the ability of MLC to promote gene flow across rivers has not been demonstrated empirically. Here, we test several predictions of MLC-mediated gene flow in populations of North American ground skinks (Scincella lateralis separated by a well-established riverine barrier, the Mississippi River: 1 individuals collected from within meander cutoffs should be more closely related to individuals across the river than on the same side, 2 individuals within meander cutoffs should contain more immigrants than individuals away from meander cutoffs, 3 immigration rates estimated across the river should be highest in the direction of the cutoff event, and 4 the distribution of alleles native to one side of the river should be better predicted by the historical rather than current path of the river. To test these predictions we sampled 13 microsatellite loci and mitochondrial DNA from ground skinks collected near three ancient meander loops. These predictions were generally supported by genetic data, although support was stronger for mtDNA than for microsatellite data. Partial support for genetic divergence of samples within ancient meander loops also provides evidence for the MLC hypothesis. Although a role for MLC-mediated gene flow was supported here for ground skinks, the transient nature of river channels and morphologies may limit the long-term importance of MLC in stemming population divergence across major rivers.

  10. Prospects for the measurement of the single-top $t$-channel cross section in the muon channel with 200~pb$^{-1

    CERN Document Server

    CMS Collaboration

    2009-01-01

    We report on a study aiming at an early observation of single-top events produced in the $t$ channel in proton-proton collisions, at a centre-of-mass energy of $\\sqrt{s} = 10$ TeV, in the decay channel $t\\to bW\\to b\\mu\

  11. Rip currents and alongshore flows in single channels dredged in the surf zone

    Science.gov (United States)

    Moulton, Melissa; Elgar, Steve; Raubenheimer, Britt; Warner, John C.; Kumar, Nirnimesh

    2017-01-01

    To investigate the dynamics of flows near nonuniform bathymetry, single channels (on average 30 m wide and 1.5 m deep) were dredged across the surf zone at five different times, and the subsequent evolution of currents and morphology was observed for a range of wave and tidal conditions. In addition, circulation was simulated with the numerical modeling system COAWST, initialized with the observed incident waves and channel bathymetry, and with an extended set of wave conditions and channel geometries. The simulated flows are consistent with alongshore flows and rip-current circulation patterns observed in the surf zone. Near the offshore-directed flows that develop in the channel, the dominant terms in modeled momentum balances are wave-breaking accelerations, pressure gradients, advection, and the vortex force. The balances vary spatially, and are sensitive to wave conditions and the channel geometry. The observed and modeled maximum offshore-directed flow speeds are correlated with a parameter based on the alongshore gradient in breaking-wave-driven-setup across the nonuniform bathymetry (a function of wave height and angle, water depths in the channel and on the sandbar, and a breaking threshold) and the breaking-wave-driven alongshore flow speed. The offshore-directed flow speed increases with dissipation on the bar and reaches a maximum (when the surf zone is saturated) set by the vertical scale of the bathymetric variability.

  12. How to resolve microsecond current fluctuations in single ion channels: The power of beta distributions

    Science.gov (United States)

    Schroeder, Indra

    2015-01-01

    Abstract A main ingredient for the understanding of structure/function correlates of ion channels is the quantitative description of single-channel gating and conductance. However, a wealth of information provided from fast current fluctuations beyond the temporal resolution of the recording system is often ignored, even though it is close to the time window accessible to molecular dynamics simulations. This kind of current fluctuations provide a special technical challenge, because individual opening/closing or blocking/unblocking events cannot be resolved, and the resulting averaging over undetected events decreases the single-channel current. Here, I briefly summarize the history of fast-current fluctuation analysis and focus on the so-called “beta distributions.” This tool exploits characteristics of current fluctuation-induced excess noise on the current amplitude histograms to reconstruct the true single-channel current and kinetic parameters. A guideline for the analysis and recent applications demonstrate that a construction of theoretical beta distributions by Markov Model simulations offers maximum flexibility as compared to analytical solutions. PMID:26368656

  13. Single channel and WDM transmission of 28 Gbaud zero-guard-interval CO-OFDM.

    Science.gov (United States)

    Zhuge, Qunbi; Morsy-Osman, Mohamed; Mousa-Pasandi, Mohammad E; Xu, Xian; Chagnon, Mathieu; El-Sahn, Ziad A; Chen, Chen; Plant, David V

    2012-12-10

    We report on the experimental demonstration of single channel 28 Gbaud QPSK and 16-QAM zero-guard-interval (ZGI) CO-OFDM transmission with only 1.34% overhead for OFDM processing. The achieved transmission distance is 5120 km for QPSK assuming a 7% forward error correction (FEC) overhead, and 1280 km for 16-QAM assuming a 20% FEC overhead. We also demonstrate the improved tolerance of ZGI CO-OFDM to residual inter-symbol interference compared to reduced-guard-interval (RGI) CO-OFDM. In addition, we report an 8-channel wavelength-division multiplexing (WDM) transmission of 28 Gbaud QPSK ZGI CO-OFDM signals over 4160 km.

  14. Deflection of high energy channeled charged particles by elastically bent silicon single crystals

    International Nuclear Information System (INIS)

    Gibson, W.M.; Kim, I.J.; Pisharodoy, M.; Salman, S.M.; Sun, C.R.; Wang, G.H.; Wijayawardana, R.; Forster, J.S.; Mitchell, I.V.; Baker, S.I.; Carrigan, R.A. Jr.; Toohig, T.E.; Avdeichikov, V.V.; Ellison, J.A.; Siffert, P.

    1984-01-01

    An experiment has been carried out to observe the deflection of charged particles by planar channeling in bent single crystals of silicon for protons with energy up to 180 GeV. Anomolous loss of particles from the center point of a three point bending apparatus was observed at high incident particle energy. This effect has been exploited to fashion a 'dechanneling spectrometer' to study dechanneling effects due to centripital displacement of channeled particle trajectories in a bent crystal. The bending losses generally conform to the predictions of calculations based on a classical model. (orig.)

  15. Characterization of ryanodine receptor type 1 single channel activity using "on-nucleus" patch clamp.

    Science.gov (United States)

    Wagner, Larry E; Groom, Linda A; Dirksen, Robert T; Yule, David I

    2014-08-01

    In this study, we provide the first description of the biophysical and pharmacological properties of ryanodine receptor type 1 (RyR1) expressed in a native membrane using the on-nucleus configuration of the patch clamp technique. A stable cell line expressing rabbit RyR1 was established (HEK-RyR1) using the FLP-in 293 cell system. In contrast to untransfected cells, RyR1 expression was readily demonstrated by immunoblotting and immunocytochemistry in HEK-RyR1 cells. In addition, the RyR1 agonists 4-CMC and caffeine activated Ca(2+) release that was inhibited by high concentrations of ryanodine. On nucleus patch clamp was performed in nuclei prepared from HEK-RyR1 cells. Raising the [Ca(2+)] in the patch pipette resulted in the appearance of a large conductance cation channel with well resolved kinetics and the absence of prominent subconductance states. Current versus voltage relationships were ohmic and revealed a chord conductance of ∼750pS or 450pS in symmetrical 250mM KCl or CsCl, respectively. The channel activity was markedly enhanced by caffeine and exposure to ryanodine resulted in the appearance of a subconductance state with a conductance ∼40% of the full channel opening with a Po near unity. In total, these properties are entirely consistent with RyR1 channel activity. Exposure of RyR1 channels to cyclic ADP ribose (cADPr), nicotinic acid adenine dinucleotide phosphate (NAADP) or dantrolene did not alter the single channel activity stimulated by Ca(2+), and thus, it is unlikely these molecules directly modulate RyR1 channel activity. In summary, we describe an experimental platform to monitor the single channel properties of RyR channels. We envision that this system will be influential in characterizing disease-associated RyR mutations and the molecular determinants of RyR channel modulation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Unidirectional transport of a bead on a single microtubule immobilized in a submicrometre channel

    Science.gov (United States)

    Yokokawa, Ryuji; Yoshida, Yumi; Takeuchi, Shoji; Kon, Takahide; Fujita, Hiroyuki

    2006-01-01

    Artificial nano-scale transportation is demonstrated by reconstructing the intracellular transport in a living cell. The transport system is established on two novel techniques: one is the introduction of a single microtubule filament with controlled polarity in a microfabricated submicrometre channel; the other is the immobilization technique of microtubules by a mercury lamp. To transport a kinesin-coated bead in a designated direction, each microtubule filament is polarly oriented by in vitro gliding assay, in which microtubules are carried by the movement of kinesin immobilized on the channel surface. Then, microtubules are immobilized by exposing kinesin to the mercury lamp, which inactivates kinesin but not microtubules. A kinesin-coated bead is newly introduced and carried on the microtubule from one end of the channel to the other as designed. This is an essential component to build up an integrated nano-scale transport system driven by motor proteins.

  17. Evidence for s-channel single top quark production at D0

    CERN Multimedia

    CERN. Geneva

    2013-01-01

    We present the measurements of the cross sections for the two main production modes of single top quarks at the Tevatron with 9.7/fb of data collected by the D0 detector. The analysis employs three different multivariate techniques which are combined to extract the small signal from the large backgrounds in the W+jets final state. We measure independently the t-channel (tqb) and the s-channel (tb), and obtain a lower limit on the CKM matrix element |Vtb|>0.92 at 95% CL. The results are compared with physics beyond the SM. The presence of the s-channel production is established in the D0 data with a significance of more than 3 standard deviations for the first time.

  18. Single-channel labyrinthine metasurfaces as perfect sound absorbers with tunable bandwidth

    Science.gov (United States)

    Liu, Liu; Chang, Huiting; Zhang, Chi; Hu, Xinhua

    2017-08-01

    Perfect sound absorbers with a deep-subwavelength thickness are important to applications such as noise reduction and sound detection. But their absorption bandwidths are usually narrow and difficult to adjust. A recent solution for this problem relies on multiple-resonator metasurfaces, which are hard to fabricate. Here, we report on the design, fabrication, and characterization of a single-channel labyrinthine metasurface, which allows total sound absorption at resonant frequency when appropriate amounts of porous media (or critical sound losses) are introduced in the channels. The absorption bandwidth can be tuned by changing the cross-sectional areas of channels. A tradeoff is found between the absorption bandwidth and the metasurface thickness. However, large tunability in the relative absorption bandwidth (from 17% to 121%) is still attainable by such metasurfaces with a deep-subwavelength thickness (0.03-0.13λ).

  19. Energy transduction and signal averaging of fluctuating electric fields by a single protein ion channel.

    Science.gov (United States)

    Verdia-Baguena, C; Gomez, V; Cervera, J; Ramirez, P; Mafe, S

    2016-12-21

    We demonstrate the electrical rectification and signal averaging of fluctuating signals using a biological nanostructure in aqueous solution: a single protein ion channel inserted in the lipid bilayer characteristic of cell membranes. The conversion of oscillating, zero time-average potentials into directional currents permits charging of a load capacitor to significant steady-state voltages within a few minutes in the case of the outer membrane porin F (OmpF) protein, a bacterial channel of Escherichia coli. The experiments and simulations show signal averaging effects at a more fundamental level than the traditional cell and tissue scales, which are characterized by ensembles of many ion channels operating simultaneously. The results also suggest signal transduction schemes with bio-electronic interfaces and ionic circuits where soft matter nanodiodes can be coupled to conventional electronic elements.

  20. An Efficient Channel Model for OFDM and Time Domain Single Carrier Transmission Using Impulse Responses

    Directory of Open Access Journals (Sweden)

    Tariq Jamil Saifullah Khanzada

    2012-01-01

    Full Text Available The OFDM (Orthogonal Frequency Division Multiplexing is well-known, most utilized wideband communication technique of the current era. SCT (Single Carrier Transmission provides equivalent performance in time domain while decision equalizer is implemented in frequency domain. SCT annihilates the ICT (Inter Carrier Interference and the PAPR (Peak to Average Power Ratio which is inherent to OFDM and degrades its performance in time varying channels. An efficient channel model is presented in this contribution, to implement OFDM and SCT in time domain using impulse responses. Both OFDM and SCT models are derived dialectically to model the channel impulse responses. Our model enhances the performance of time domain SCT compared with OFDM and subsides the PAPR and ICI problems of OFDM. SCT is implemented at symbol level contained in blocks. Simulation results implementing Digital Radio Monadiale (DRM assert the performance gain of SCT over OFDM.

  1. Gain Enhancement of Low-Profile, Electrically Small Capacitive Feed Antennas Using Stacked Meander Lines

    Directory of Open Access Journals (Sweden)

    Kazuki Ide

    2010-01-01

    Full Text Available The present paper describes the gain enhancement of a small and low-profile linear antenna with capacitive feed (C-feed using three metallic layers. The antenna has very small leakage current on the outer conductor of the coaxial cable and can easily control the imaginary part of the input impedance. The gain of the stacked three-layer meander line antenna, with the meander line in the middle layer being opposite to that of the other two layers, has increased by around 7 dB compared to the single layered C-feed antenna. The antenna gain is discussed based on simulated and measured results, which demonstrates that the antenna has successfully achieved the acceptable impedance and sufficient gain for mobile terminals and RFID tags.

  2. Influence of riparian vegetation on near-bank flow structure and erosion rates on a large meandering river

    Science.gov (United States)

    Konsoer, K. M.; Rhoads, B. L.; Langendoen, E. J.; Johnson, K.; Ursic, M.

    2012-12-01

    Rates of meander migration are dependent upon dynamic interactions between planform geometry, three-dimensional flow structure, sediment transport, and the erodibility and geotechnical properties of the channel banks and floodplains. Riparian vegetation can greatly reduce the rate of migration through root-reinforcement and increased flow resistance near the bank. In particular, forested riverbanks can also provide large woody debris (LWD) to the channel, and if located near the outer bank, can act to amour the bank by disrupting three-dimensional flow patterns and redirecting flow away from the bank-toe, the locus of erosion in meandering rivers. In this paper, three-dimensional flow patterns and migration rates are compared for two meander bends, one forested and one non-forested, on the Wabash River, near Grayville, Illinois. Flow data were obtained using acoustic Doppler current profilers (ADCP) for two large flow events in May and June 2011. LWD was mapped using a terrestrial LiDAR survey, and residence times for the LWD were estimated by comparing the survey data to time-series aerial photography. Rates of migration and planform evolution were determined through time-series analysis of aerial photography from 1938-2011. Results from this study show that near-bank LWD can have a significant influence on flow patterns through a meander bend and can disrupt helical flow near the outer bank, thereby reducing the effect of the high velocity core on the toe of the bank. Additionally, these effects influence migration rates and the planform evolution of meandering rivers.

  3. The Spatial Distribution of Bed Sediment on Fluvial System: A Mini Review of the Aceh Meandering River

    Directory of Open Access Journals (Sweden)

    Muhammad Irham

    2016-08-01

    Full Text Available Dynamic interactions of hydrological and geomorphological processes in the fluvial system result in accumulated deposit on the bed because the capacity to carry sediment has been exceeded. The bed load of the Aceh fluvial system is primarily generated by mechanical weathering resulting in boulders, pebbles, and sand, which roll or bounce along the river bed forming temporary deposits as bars on the insides of meander bends, as a result of a loss of transport energy in the system. This dynamic controls the style and range of deposits in the Aceh River. This study focuses on the spatial distribution of bed-load transport of the Aceh River. Understanding the spatial distribution of deposits facilitates the reconstruction of the changes in controlling factors during accumulation of deposits. One of the methods can be done by sieve analysis of sediment, where the method illuminates the distribution of sediment changes associated with channel morphology under different flow regimes. Hence, the purpose of this mini review is to investigate how the sediment along the river meander spatially dispersed. The results demonstrate that channel deposits in the Aceh River are formed from four different type of materials: pebble deposited along upstream left bank; sand located on the upstream, downstream, and along meander belts; and silt and clay located along the cut bank of meander bends. Because of different depositional pattern, the distribution of the sediment along the river can be used as a surrogate to identify bank stability, as well as to predict critical geometry for meander bend initiation

  4. Molecular and functional identification of cyclic AMP-sensitive BKCa potassium channels (ZERO variant) and L-type voltage-dependent calcium channels in single rat juxtaglomerular cells

    DEFF Research Database (Denmark)

    Friis, Ulla G; Jørgensen, Finn; Andreasen, Ditte

    2003-01-01

    This study aimed at identifying the type and functional significance of potassium channels and voltage-dependent calcium channels (Ca(v)) in single rat JG cells using whole-cell patch clamp. Single JG cells displayed outward rectification at positive membrane potentials and limited net currents......, respectively. Double immunofluorescence confirmed the presence of BKCa and renin in the same cell. cAMP increased the outward current by 1.6-fold, and this was inhibited by 74% with iberiotoxin. Expression of the cAMP-sensitive splice variant (ZERO) of BKCa was confirmed in single-sampled JG cells by RT...... no effect. We conclude that JG cells express functional cAMP-sensitive BKCa channels (the ZERO splice variant) and voltage-dependent L-type Ca2+ channels....

  5. Charging the quantum capacitance of graphene with a single biological ion channel.

    Science.gov (United States)

    Wang, Yung Yu; Pham, Ted D; Zand, Katayoun; Li, Jinfeng; Burke, Peter J

    2014-05-27

    The interaction of cell and organelle membranes (lipid bilayers) with nanoelectronics can enable new technologies to sense and measure electrophysiology in qualitatively new ways. To date, a variety of sensing devices have been demonstrated to measure membrane currents through macroscopic numbers of ion channels. However, nanoelectronic based sensing of single ion channel currents has been a challenge. Here, we report graphene-based field-effect transistors combined with supported lipid bilayers as a platform for measuring, for the first time, individual ion channel activity. We show that the supported lipid bilayers uniformly coat the single layer graphene surface, acting as a biomimetic barrier that insulates (both electrically and chemically) the graphene from the electrolyte environment. Upon introduction of pore-forming membrane proteins such as alamethicin and gramicidin A, current pulses are observed through the lipid bilayers from the graphene to the electrolyte, which charge the quantum capacitance of the graphene. This approach combines nanotechnology with electrophysiology to demonstrate qualitatively new ways of measuring ion channel currents.

  6. Single Channel Analysis of Isoflurane and Ethanol Enhancement of Taurine-Activated Glycine Receptors.

    Science.gov (United States)

    Kirson, Dean; Todorovic, Jelena; Mihic, S John

    2018-01-01

    The amino acid taurine is an endogenous ligand acting on glycine receptors (GlyRs), which is released by astrocytes in many brain regions, such as the nucleus accumbens and prefrontal cortex. Taurine is a partial agonist with an efficacy significantly lower than that of glycine. Allosteric modulators such as ethanol and isoflurane produce leftward shifts of glycine concentration-response curves but have no effects at saturating glycine concentrations. In contrast, in whole-cell electrophysiology studies these modulators increase the effects of saturating taurine concentrations. A number of possible mechanisms may explain these enhancing effects, including modulator effects on conductance, channel open times, or channel closed times. We used outside-out patch-clamp single channel electrophysiology to investigate the mechanism of action of 200 mM ethanol and 0.55 mM isoflurane in enhancing the effects of a saturating concentration of taurine. Neither modulator enhanced taurine-mediated conductance. Isoflurane increased the probability of channel opening. Isoflurane also increased the lifetimes of the two shortest open dwell times while both agents decreased the likelihood of occurrence of the longest-lived intracluster channel-closing events. The mechanism of enhancement of GlyR functioning by these modulators is dependent on the efficacy of the agonist activating the receptor and the concentration of agonist tested. Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics.

  7. Single Channel Quantum Color Image Encryption Algorithm Based on HSI Model and Quantum Fourier Transform

    Science.gov (United States)

    Gong, Li-Hua; He, Xiang-Tao; Tan, Ru-Chao; Zhou, Zhi-Hong

    2018-01-01

    In order to obtain high-quality color images, it is important to keep the hue component unchanged while emphasize the intensity or saturation component. As a public color model, Hue-Saturation Intensity (HSI) model is commonly used in image processing. A new single channel quantum color image encryption algorithm based on HSI model and quantum Fourier transform (QFT) is investigated, where the color components of the original color image are converted to HSI and the logistic map is employed to diffuse the relationship of pixels in color components. Subsequently, quantum Fourier transform is exploited to fulfill the encryption. The cipher-text is a combination of a gray image and a phase matrix. Simulations and theoretical analyses demonstrate that the proposed single channel quantum color image encryption scheme based on the HSI model and quantum Fourier transform is secure and effective.

  8. Measurement of top quark polarisation in $t$-channel single top quark production

    CERN Document Server

    Khachatryan, Vardan; Tumasyan, Armen; Adam, Wolfgang; Aşılar, Ece; Bergauer, Thomas; Brandstetter, Johannes; Brondolin, Erica; Dragicevic, Marko; Erö, Janos; Flechl, Martin; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hartl, Christian; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Knünz, Valentin; König, Axel; Krammer, Manfred; Krätschmer, Ilse; Liko, Dietrich; Matsushita, Takashi; Mikulec, Ivan; Rabady, Dinyar; Rahbaran, Babak; Rohringer, Herbert; Schieck, Jochen; Schöfbeck, Robert; Strauss, Josef; Treberer-Treberspurg, Wolfgang; Waltenberger, Wolfgang; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Alderweireldt, Sara; Cornelis, Tom; De Wolf, Eddi A; Janssen, Xavier; Knutsson, Albert; Lauwers, Jasper; Luyckx, Sten; Van De Klundert, Merijn; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Abu Zeid, Shimaa; Blekman, Freya; D'Hondt, Jorgen; Daci, Nadir; De Bruyn, Isabelle; Deroover, Kevin; Heracleous, Natalie; Keaveney, James; Lowette, Steven; Moreels, Lieselotte; Olbrechts, Annik; Python, Quentin; Strom, Derek; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Van Parijs, Isis; Barria, Patrizia; Brun, Hugues; Caillol, Cécile; Clerbaux, Barbara; De Lentdecker, Gilles; Fasanella, Giuseppe; Favart, Laurent; Grebenyuk, Anastasia; Karapostoli, Georgia; Lenzi, Thomas; Léonard, Alexandre; Maerschalk, Thierry; Marinov, Andrey; Perniè, Luca; Randle-conde, Aidan; Seva, Tomislav; Vander Velde, Catherine; Vanlaer, Pascal; Yonamine, Ryo; Zenoni, Florian; Zhang, Fengwangdong; Beernaert, Kelly; Benucci, Leonardo; Cimmino, Anna; Crucy, Shannon; Dobur, Didar; Fagot, Alexis; Garcia, Guillaume; Gul, Muhammad; Mccartin, Joseph; Ocampo Rios, Alberto Andres; Poyraz, Deniz; Ryckbosch, Dirk; Salva Diblen, Sinem; Sigamani, Michael; Tytgat, Michael; Van Driessche, Ward; Yazgan, Efe; Zaganidis, Nicolas; Basegmez, Suzan; Beluffi, Camille; Bondu, Olivier; Brochet, Sébastien; Bruno, Giacomo; Caudron, Adrien; Ceard, Ludivine; Da Silveira, Gustavo Gil; Delaere, Christophe; Favart, Denis; Forthomme, Laurent; Giammanco, Andrea; Hollar, Jonathan; Jafari, Abideh; Jez, Pavel; Komm, Matthias; Lemaitre, Vincent; Mertens, Alexandre; Musich, Marco; Nuttens, Claude; Perrini, Lucia; Pin, Arnaud; Piotrzkowski, Krzysztof; Popov, Andrey; Quertenmont, Loic; Selvaggi, Michele; Vidal Marono, Miguel; Beliy, Nikita; Hammad, Gregory Habib; Aldá Júnior, Walter Luiz; Alves, Fábio Lúcio; Alves, Gilvan; Brito, Lucas; Correa Martins Junior, Marcos; Hamer, Matthias; Hensel, Carsten; Mora Herrera, Clemencia; Moraes, Arthur; Pol, Maria Elena; Rebello Teles, Patricia; Belchior Batista Das Chagas, Ewerton; Carvalho, Wagner; Chinellato, Jose; Custódio, Analu; Melo Da Costa, Eliza; De Jesus Damiao, Dilson; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Huertas Guativa, Lina Milena; Malbouisson, Helena; Matos Figueiredo, Diego; Mundim, Luiz; Nogima, Helio; Prado Da Silva, Wanda Lucia; Santoro, Alberto; Sznajder, Andre; Tonelli Manganote, Edmilson José; Vilela Pereira, Antonio; Ahuja, Sudha; Bernardes, Cesar Augusto; De Souza Santos, Angelo; Dogra, Sunil; Tomei, Thiago; De Moraes Gregores, Eduardo; Mercadante, Pedro G; Moon, Chang-Seong; Novaes, Sergio F; Padula, Sandra; Romero Abad, David; Ruiz Vargas, José Cupertino; Aleksandrov, Aleksandar; Hadjiiska, Roumyana; Iaydjiev, Plamen; Rodozov, Mircho; Stoykova, Stefka; Sultanov, Georgi; Vutova, Mariana; Dimitrov, Anton; Glushkov, Ivan; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Ahmad, Muhammad; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Chen, Mingshui; Cheng, Tongguang; Du, Ran; Jiang, Chun-Hua; Plestina, Roko; Romeo, Francesco; Shaheen, Sarmad Masood; Spiezia, Aniello; Tao, Junquan; Wang, Chunjie; Wang, Zheng; Zhang, Huaqiao; Asawatangtrakuldee, Chayanit; Ban, Yong; Li, Qiang; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Wang, Dayong; Xu, Zijun; Avila, Carlos; Cabrera, Andrés; Chaparro Sierra, Luisa Fernanda; Florez, Carlos; Gomez, Juan Pablo; Gomez Moreno, Bernardo; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Puljak, Ivica; Ribeiro Cipriano, Pedro M; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Kadija, Kreso; Luetic, Jelena; Micanovic, Sasa; Sudic, Lucija; Attikis, Alexandros; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Rykaczewski, Hans; Bodlak, Martin; Finger, Miroslav; Finger Jr, Michael; Abdelalim, Ahmed Ali; Awad, Adel; El Sawy, Mai; Mahrous, Ayman; Radi, Amr; Calpas, Betty

    2016-04-13

    A first measurement of the top quark spin asymmetry, sensitive to the top quark polarisation, in $t$-channel single top quark production is presented. It is based on a sample of pp collisions at a centre-of-mass energy of 8 TeV corresponding to an integrated luminosity of 19.7 fb$^{-1}$. A high-purity sample of $t$-channel single top quark events with an isolated muon is selected. Signal and background components are estimated using a fit to data. A differential cross section measurement, corrected for detector effects, of an angular observable sensitive to the top quark polarisation is performed. The differential distribution is used to extract a top quark spin asymmetry of 0.26 $\\pm$ 0.03 (stat) $\\pm$ 0.10 (syst), which is compatible with a $p$-value of 4.6% with the standard model prediction of 0.44.

  9. Self-aligned multi-channel superconducting nanowire single-photon detectors.

    Science.gov (United States)

    Cheng, Risheng; Guo, Xiang; Ma, Xiaosong; Fan, Linran; Fong, King Y; Poot, Menno; Tang, Hong X

    2016-11-28

    We describe a micromachining process to allow back-side coupling of an array of single-mode telecommunication fibers to individual superconducting nanowire single photon detectors (SNSPDs). This approach enables a back-illuminated detector structure which separates the optical access and electrical readout on two sides of the chip and thus allows for compact integration of multi-channel detectors. As proof of principle, we show the integration of four detectors on the same silicon chip with two different designs and their performances are compared. In the optimized design, the device shows saturated system detection efficiency of 16% while the dark count rate is less than 20 Hz, all achieved without the use of metal reflectors or distributed Bragg reflectors (DBRs). This back-illumination approach also eliminates the cross-talk between different detection channels.

  10. Single-channel data-validation technique for ΔP cells in turbulent flow

    International Nuclear Information System (INIS)

    Goodrich, L.D.; Brower, R.W.

    1983-01-01

    This paper discusses a single-channel-analysis, data-validation technique which is applicable to all flow-measuring devices in turbulent conditions, can be applied in either real time or batch mode, and allows online correction of zero offset and slope coefficients. This technique of validating flow measurements eliminates the need for multiple measuring devices, thus reducing the complexity of the overall instrumentation system

  11. Linking Meander Initation to Instability in the Cross-Sectional Sediment Transport Field

    Science.gov (United States)

    Eaton, B. C.

    2005-12-01

    Recent theoretical and experimental work on reach-scale channel dynamics suggests that stream channel response to changes in the discharge or sediment supply regime produce adjustments that are consistent with the optimality criteria (or extremal hypotheses) proposed by rational regime modellers. However, a general form of the optimality criteria based on the maximization of system-scale flow resistance permits multiple channel responses to the same imposed change, and is thus inadequate for predicting channel response, absent additional information. The way forward is to identify the geomorphic processes that produce various possible channel responses, and to develop an understanding of the conditions under which these processes may or may not be effective. Using a simple analytic model relating local sediment transport capacity to variance in the transverse shear stress distribution I develop a physically based conceptual model of the initiation of meandering in straight, bedload dominated streams as a result of a feedback mechanism. This corresponds to a channel response that is dominated by changes the energy slope, which appears to be dominant in channels having relatively erodible banks and transporting their bed material load at conditions near the threshold for entrainment. The feedback maximizes the cross sectional shear stress variance and, in order to achieve stability, minimizes the energy slope at repeated locations along the channel. These locations develop into pools in a fully developed meandering channel; they represent attractor states wherein sediment continuity is satisfied using the least possible energy expenditure per unit length of channel. Between two successive pools, a stream occupies a metastable, higher energy state (corresponding to a riffle) that requires greater energy expenditure per unit length of channel to transport the same volume of sediment. The model links processes at the scale of a channel width to adjustments of the

  12. Single-channel blind separation using pseudo-stereo mixture and complex 2-D histogram.

    Science.gov (United States)

    Tengtrairat, N; Gao, Bin; Woo, W L; Dlay, S S

    2013-11-01

    A novel single-channel blind source separation (SCBSS) algorithm is presented. The proposed algorithm yields at least three benefits of the SCBSS solution: 1) resemblance of a stereo signal concept given by one microphone; 2) independent of initialization and a priori knowledge of the sources; and 3) it does not require iterative optimization. The separation process consists of two steps: 1) estimation of source characteristics, where the source signals are modeled by the autoregressive process and 2) construction of masks using only the single-channel mixture. A new pseudo-stereo mixture is formulated by weighting and time-shifting the original single-channel mixture. This creates an artificial mixing system whose parameters will be estimated through our proposed weighted complex 2-D histogram. In this paper, we derive the separability of the proposed mixture model. Conditions required for unique mask construction based on maximum likelihood are also identified. Finally, experimental testing on both synthetic and real-audio sources is conducted to verify that the proposed algorithm yields superior performance and is computationally very fast compared with existing methods.

  13. Convective nature of the planimetric instability in meandering river dynamics.

    Science.gov (United States)

    Camporeale, Carlo; Ridolfi, Luca

    2006-02-01

    The convective nature of the linear instability of meandering river dynamics is analytically demonstrated and the corresponding Green's function is derived. The wave packet due to impulsive disturbance migrates along a river either downstream or upstream, depending on the subresonant or superresonant conditions. The influence of the parameters that govern the meandering process is shown and the role of the fluid dynamic detail used to describe the morphodynamic problem is discussed. A numerical simulation of the river planimetry is also developed.

  14. Cycloidal meandering of a mesoscale anticyclonic eddy

    Science.gov (United States)

    Kizner, Ziv; Shteinbuch-Fridman, Biana; Makarov, Viacheslav; Rabinovich, Michael

    2017-08-01

    By applying a theoretical approach, we propose a hypothetical scenario that might explain some features of the movement of a long-lived mesoscale anticyclone observed during 1990 in the Bay of Biscay [R. D. Pingree and B. Le Cann, "Three anticyclonic slope water oceanic eddies (SWODDIES) in the southern Bay of Biscay in 1990," Deep-Sea Res., Part A 39, 1147 (1992)]. In the remote-sensing infrared images, at the initial stage of observations, the anticyclone was accompanied by two cyclonic eddies, so the entire structure appeared as a tripole. However, at later stages, only the anticyclone was seen in the images, traveling generally west. Unusual for an individual eddy were the high speed of its motion (relative to the expected planetary beta-drift) and the presence of almost cycloidal meanders in its trajectory. Although surface satellites seem to have quickly disappeared, we hypothesize that subsurface satellites continued to exist, and the coherence of the three vortices persisted for a long time. A significant perturbation of the central symmetry in the mutual arrangement of three eddies constituting a tripole can make reasonably fast cycloidal drift possible. This hypothesis is tested with two-layer contour-dynamics f-plane simulations and with finite-difference beta-plane simulations. In the latter case, the interplay of the planetary beta-effect and that due to the sloping bottom is considered.

  15. Ultra-compact 32-channel system for time-correlated single-photon counting measurements

    Science.gov (United States)

    Antonioli, S.; Cuccato, A.; Miari, L.; Labanca, I.; Rech, I.; Ghioni, M.

    2013-05-01

    Modern Time-Correlated Single-Photon Counting applications require to detect spectral and temporal fluorescence data simultaneously and from different areas of the analyzed sample. These rising quests have led the development of multichannel systems able to perform high count rate and high performance analysis. In this work we describe a new 32-channel TCSPC system designed to be used in modern setups. The presented module consists of four independent 8-channel TCSPC boards, each of them including two 4-channel Time-Amplitude Converter arrays. These TAC arrays are built-in 0.35 μm Si-Ge BiCMOS technology and are characterized by low crosstalk, high resolution, high conversion rate and variable full-scale range. The 8-channel TCSPC board implements an 8-channel ADC to sample the TAC outputs, an FPGA to record and organize the measurement results and a USB 2.0 interface to enable real-time data transmission to and from an external PC. Experimental results demonstrate that the acquisition system ensures high performance TCSPC measurements, in particular: high conversion rate (5 MHz), good time resolution (down to 30 psFWHM with the full scale range set to 11 ns) and low differential non-linearity (rms value lower than 0.15% of the time bin width). We design the module to be very compact and, thanks to the reduced dimensions of the 8-channel TCSPC board (95×40 mm), the whole system can be enclosed in a small aluminum case (160×125×30 mm).

  16. Secure Degrees of Freedom of the Gaussian Z Channel with Single Antenna

    Directory of Open Access Journals (Sweden)

    Xianzhong XIE

    2014-03-01

    Full Text Available This paper presents the secrecy capacity and the secure degrees of freedom of Gaussian Z channel with single antenna and confidential information. Firstly, we analysis the secrecy capacity and the upper bound of secure degrees of freedom of this channel in theory. Then, we respectively discuss the security pre-coding scheme for real Gaussian channel model and frequency selection channel model. Under the first model, through real interference alignment and cooperative jamming, we obtain the secrecy capacity and secure degrees of freedom, proving that it can reach the upper bound of secure degrees of freedom in theory. While, under the second one, a strong security pre-coding algorithm is proposed, which is based on the fact that sparse matrix has strong hash property. Next, we arrange interference with interference alignment and the receivers process their received signal through zero forcing algorithm. At last, the messages are reconstructed with maximum likelihood decoding, where it shows that the algorithm can asymptotically achieve the optimal secrecy capacity.

  17. Single-top s channel cross-section measurement with the ATLAS detector

    CERN Document Server

    Monini, Caterina; Lucotte, Arnaud

    The work reported in this thesis is aimed at measuring with the ATLAS detector the only mechanism of top quark electroweak production which has not yet been observed at the Large Hadron Collider: the s-channel. Its interest relies in the confirmation of the Standard Model predictions but, as well, in the possibility of constraining several new physics scenarios when comparing the s-channel cross section with the one of the other single top production modes (the Wt and t-channel). After a general introduction upon top physics and the experimental setup employed for the detection and the reconstruction of the physics objects, we present two analyses realized with proton-proton collisions collected by the ATLAS detector at a center of mass energy of 7 and 8 TeV. Since the s-channel production is characterized by a very low purity and, at the same time, is not favoured at the LHC because it proceeds via quark-antiquark annihilation, a multivariate approach is applied in both cases to discriminate the signal. For ...

  18. Impact of multiple lymphatic channel drainage to a single nodal basin on outcomes in melanoma.

    Science.gov (United States)

    Wall, James K; Florero, Marilyn; Accortt, Neil A; Allen, Robert; Kashani-Sabet, Mohamed; Morita, Eugene; Leong, Stanley P L

    2007-08-01

    To determine the impact of multiple lymphatic channels (MLCs) on outcome in melanoma. Retrospective cohort study. Academic tertiary care center. Of 1198 consecutive selective sentinel lymphadenectomies performed from 1995 to 2000 for primary invasive melanoma, 502 patients were identified with extremity or truncal melanoma that drained to a single nodal basin. Three cohorts were formed based on lymphatic channels (none, single, and multiple). Tumors with drainage to multiple nodal basins as well as all head and neck tumors were excluded. Multiple variables, including patterns of lymphatic drainage, were analyzed for impact on disease-free and overall survival. Demographics were similar among groups, with a median follow-up of 5.6 years. Univariate analysis revealed MLCs as an independent risk factor for both disease-free (P = .04) and overall survival (P = .003). Multivariate analysis confirmed that tumor depth, sentinel lymph node status, and MLCs were risk factors for both disease-free and overall survival. Kaplan-Meier analysis showed worse survival in the MLCs group. Our study reveals that MLCs are an independent risk factor for recurrence and mortality in melanoma. Multiple lymphatic channels may facilitate the process of metastasis.

  19. Constructions of secure entanglement channels assisted by quantum dots inside single-sided optical cavities

    Science.gov (United States)

    Heo, Jino; Kang, Min-Sung; Hong, Chang-Ho; Choi, Seong-Gon; Hong, Jong-Phil

    2017-08-01

    We propose quantum information processing schemes to generate and swap entangled states based on the interactions between flying photons and quantum dots (QDs) confined within optical cavities for quantum communication. To produce and distribute entangled states (Bell and Greenberger-Horne-Zeilinger [GHZ] states) between the photonic qubits of flying photons of consumers (Alice and Bob) and electron-spin qubits of a provider (trust center, or TC), the TC employs the interactions of the QD-cavity system, which is composed of a charged QD (negatively charged exciton) inside a single-sided cavity. Subsequently, the TC constructs an entanglement channel (Bell state and 4-qubit GHZ state) to link one consumer with another through entanglement swapping, which can be realized to exploit a probe photon with interactions of the QD-cavity systems and single-qubit measurements without Bell state measurement, for quantum communication between consumers. Consequently, the TC, which has quantum nodes (QD-cavity systems), can accomplish constructing the entanglement channel (authenticated channel) between two separated consumers from the distributions of entangled states and entanglement swapping. Furthermore, our schemes using QD-cavity systems, which are feasible with a certain probability of success and high fidelity, can be experimentally implemented with technology currently in use.

  20. Sensitivity of bimodal listeners to interaural time differences with modulated single- and multiple-channel stimuli.

    Science.gov (United States)

    Francart, Tom; Lenssen, Anneke; Wouters, Jan

    2011-01-01

    In a previous study, it was shown that users of a cochlear implant and a contralateral hearing aid are sensitive to interaural time differences (ITDs). In the current study, we investigated (1) the influence on ITD sensitivity of bilaterally varying the place of excitation in the cochlea and of modulation frequency, and (2) the sensitivity to ITD with a 3-channel stimulus generated using continuous-interleaved-sampling (CIS)-like processing. The stimuli were (1) a high-frequency carrier (acoustic sinusoid and single-electrode electric pulse train), modulated with a half-wave-rectified low-frequency sinusoid (a so-called transposed stimulus), and (2) a 3-channel stimulus, generated by sending an acoustic click train through processing similar to the CIS strategy. Four bimodal listeners were sensitive to ITD for both stimulus types. For the first stimulus type, there was no significant influence on ITD sensitivity of the acoustic carrier frequency. Performance decreased with increasing modulation frequency with a limit of sensitivity at around 150-200 Hz. Sensitivity was similar for the single- and 3-channel stimulus. The results indicate the possibility of ITD perception with adapted clinical processors, which can lead to improved sound source localization and binaural unmasking. Copyright © 2010 S. Karger AG, Basel.

  1. Multi-Channel Adjustable DC Power Supply with Single Transformer Based on Spectral Separation

    Science.gov (United States)

    Benfeng, Zhang; Huafeng, Li; Sunan, Li

    2014-01-01

    To meet the need of multi-channel DC power supply to activate multiple macro fiber composite (MFC) material simultaneously, a novel multi-channel adjustable DC supply using single-input single-output transformer based on spectral separation is proposed. A hybrid signal containing multiple frequency bands is boosted to obtain a high-voltage signal without bands change. Several frequency selection circuits are then used to separate individual signals in different frequency band from the high-voltage signal. Finally, these signals are rectified and filtered respectively to obtain multiple channel DC voltages. The feasibility of the proposed scheme is analyzed theoretically and verified by simulation. The hybrid signal containing multiple frequency bands is constructed by MCU (Micro Control Unit) and boosted using push-pull boost circuit. Low-pass, band-pass and high-pass frequency selection circuits are used to obtain the individual high-voltage signal in different frequency bands, and the amplitude frequency response characteristics of these filters are simulated using PSpice. Experimental results prove that each part of the scheme runs reliable and the output is stable and adjustable.

  2. Measurement of Single-top t-channel Production Using ATLAS Data

    CERN Document Server

    Holzbauer, Jenny; Schwienhorst, R; Repko, W; Lapidus, L; Pratt, S

    2012-01-01

    This document reports the measurement of the single-top t-channel cross-section using data from the ATLAS detector, located at the Large Hadron Collider on the border of France and Switzerland. The data used were collected during the first half of 2011, from proton-proton collisions with a 7 TeV center-of-mass collision energy. Single-top is electroweak top-quark production and t-channel is one of the standard model production modes. To isolate this production, selections are applied to find events with a similar final state. A cut-based analysis is used to further isolate the signal using a series of selections in several orthogonal kinematic regions. Finally, a statistical analysis is performed to determine the measured cross-section and the CKM matrix element |Vtb|. The cross-section for top and anti-top production is considered separately and the resulting cross-sections are σ t+ = 59 +18 -16 pb for the positive charge channel and σ t- = 33 +13 -12 pb for the negative charge chan...

  3. 8-channel acquisition system for time-correlated single-photon counting

    Science.gov (United States)

    Antonioli, S.; Miari, L.; Cuccato, A.; Crotti, M.; Rech, I.; Ghioni, M.

    2013-06-01

    Nowadays, an increasing number of applications require high-performance analytical instruments capable to detect the temporal trend of weak and fast light signals with picosecond time resolution. The Time-Correlated Single-Photon Counting (TCSPC) technique is currently one of the preferable solutions when such critical optical signals have to be analyzed and it is fully exploited in biomedical and chemical research fields, as well as in security and space applications. Recent progress in the field of single-photon detector arrays is pushing research towards the development of high performance multichannel TCSPC systems, opening the way to modern time-resolved multi-dimensional optical analysis. In this paper we describe a new 8-channel high-performance TCSPC acquisition system, designed to be compact and versatile, to be used in modern TCSPC measurement setups. We designed a novel integrated circuit including a multichannel Time-to-Amplitude Converter with variable full-scale range, a D/A converter, and a parallel adder stage. The latter is used to adapt each converter output to the input dynamic range of a commercial 8-channel Analog-to-Digital Converter, while the integrated DAC implements the dithering technique with as small as possible area occupation. The use of this monolithic circuit made the design of a scalable system of very small dimensions (95 × 40 mm) and low power consumption (6 W) possible. Data acquired from the TCSPC measurement are digitally processed and stored inside an FPGA (Field-Programmable Gate Array), while a USB transceiver allows real-time transmission of up to eight TCSPC histograms to a remote PC. Eventually, the experimental results demonstrate that the acquisition system performs TCSPC measurements with high conversion rate (up to 5 MHz/channel), extremely low differential nonlinearity (<0.04 peak-to-peak of the time bin width), high time resolution (down to 20 ps Full-Width Half-Maximum), and very low crosstalk between channels.

  4. Cocaine-induced closures of single batrachotoxin-activated Na+ channels in planar lipid bilayers

    Science.gov (United States)

    1988-01-01

    Batrachotoxin (BTX)-activated Na+ channels from rabbit skeletal muscle were incorporated into planar lipid bilayers. These channels appear to open most of the time at voltages greater than -60 mV. Local anesthetics, including QX-314, bupivacaine, and cocaine when applied internally, induce different durations of channel closures and can be characterized as "fast" (mean closed duration less than 10 ms at +50 mV), "intermediate" (approximately 80 ms), and "slow" (approximately 400 ms) blockers, respectively. The action of these local anesthetics on the Na+ channel is voltage dependent; larger depolarizations give rise to stronger binding interactions. Both the dose-response curve and the kinetics of the cocaine-induced closures indicate that there is a single class of cocaine-binding site. QX-314, though a quaternary-amine local anesthetic, apparently competes with the same binding site. External cocaine or bupivacaine application is almost as effective as internal application, whereas external QX-314 is ineffective. Interestingly, external Na+ ions reduce the cocaine binding affinity drastically, whereas internal Na+ ions have little effect. Both the cocaine association and dissociation rate constants are altered when external Na+ ion concentrations are raised. We conclude that (a) one cocaine molecule closes one BTX-activated Na+ channel in an all-or-none manner, (b) the binding affinity of cocaine is voltage sensitive, (c) this cocaine binding site can be reached by a hydrophilic pathway through internal surface and by a hydrophobic pathway through bilayer membrane, and (d) that this binding site interacts indirectly with the Na+ ions. A direct interaction between the receptor and Na+ ions seems minimal. PMID:2851029

  5. [Study on Sleep Staging Based on Support Vector Machines and Feature Selection in Single Channel Electroencephalogram].

    Science.gov (United States)

    Lin, Xiujing; Xia, Yongming; Qian, Songrong

    2015-06-01

    Sleep electroencephalogram (EEG) is an important index in diagnosing sleep disorders and related diseases. Manual sleep staging is time-consuming and often influenced by subjective factors. Existing automatic sleep staging methods have high complexity and a low accuracy rate. A sleep staging method based on support vector machines (SVM) and feature selection using single channel EEG single is proposed in this paper. Thirty-eight features were extracted from the single channel EEG signal. Then based on the feature selection method F-Score's definition, it was extended to multiclass with an added eliminate factor in order to find proper features, which were used as SVM classifier inputs. The eliminate factor was adopted to reduce the negative interaction of features to the result. Research on the F-Score with an added eliminate factor was further accomplished with the data from a standard open source database and the results were compared with none feature selection and standard F-Score feature selection. The results showed that the present method could effectively improve the sleep staging accuracy and reduce the computation time.

  6. Flow Patterns and Morphological Changes in a Sandy Meander Bend during a Flood—Spatially and Temporally Intensive ADCP Measurement Approach

    Directory of Open Access Journals (Sweden)

    Elina Kasvi

    2017-02-01

    Full Text Available The fluvio-geomorphological processes in meander bends are spatially uneven in distribution. Typically, higher velocities and erosion take place near the outer bank beyond the bend apex, while the inner bend point bar grows laterally towards the outer bank, increasing the bend amplitude. These dynamics maintain the meander evolution. Even though this development is found in meandering rivers independent of soil or environmental characteristics, each river still seems to behave unpredictably. The special mechanisms that determine the rate and occasion of morphological changes remain unclear. The aim of this study is to offer new insights regarding flow-induced morphological changes in meander using a novel study approach. We focused on short-term and small-spatial-scale changes by conducting a spatially and temporally (daily intensive survey during a flood (a period of nine days with an ADCP attached to a remotely controlled mini-boat. Based on our analysis, the flood duration and the rate of discharge increase and decrease seems to play key roles in determining channel changes by controlling the flow velocities and depth and the backwater effect may have notable influence on the morphological processes. We discuss themes such as the interaction of inner and outer bend processes and the longer-term development of meander bends.

  7. Channel analysis for single photon underwater free space quantum key distribution.

    Science.gov (United States)

    Shi, Peng; Zhao, Shi-Cheng; Gu, Yong-Jian; Li, Wen-Dong

    2015-03-01

    We investigate the optical absorption and scattering properties of underwater media pertinent to our underwater free space quantum key distribution (QKD) channel model. With the vector radiative transfer theory and Monte Carlo method, we obtain the attenuation of photons, the fidelity of the scattered photons, the quantum bit error rate, and the sifted key generation rate of underwater quantum communication. It can be observed from our simulations that the most secure single photon underwater free space QKD is feasible in the clearest ocean water.

  8. Single-Channel Noise Reduction using Unified Joint Diagonalization and Optimal Filtering

    DEFF Research Database (Denmark)

    Nørholm, Sidsel Marie; Benesty, Jacob; Jensen, Jesper Rindom

    2014-01-01

    consider two cases, where, respectively, no distortion and distortion are incurred on the desired signal. The former can be achieved when the covariance matrix of the desired signal is rank deficient, which is the case, for example, for voiced speech. In the latter case, the covariance matrix......In this paper, the important problem of single-channel noise reduction is treated from a new perspective. The problem is posed as a filtering problem based on joint diagonalization of the covariance matrices of the desired and noise signals. More specifically, the eigenvectors from the joint...

  9. Effectiveness of diaphragmatic stimulation with single-channel electrodes in rabbits

    Directory of Open Access Journals (Sweden)

    Rodrigo Guellner Ghedini

    2013-06-01

    Full Text Available Every year, a large number of individuals become dependent on mechanical ventilation because of a loss of diaphragm function. The most common causes are cervical spinal trauma and neuromuscular diseases. We have developed an experimental model to evaluate the performance of electrical stimulation of the diaphragm in rabbits using single-channel electrodes implanted directly into the muscle. Various current intensities (10, 16, 20, and 26 mA produced tidal volumes above the baseline value, showing that this model is effective for the study of diaphragm performance at different levels of electrical stimulation

  10. New Results on Single-Channel Speech Separation Using Sinusoidal Modeling

    DEFF Research Database (Denmark)

    Mowlaee, Pejman; Christensen, Mads Græsbøll; Jensen, Søren Holdt

    2011-01-01

    We present new results on single-channel speech separation and suggest a new separation approach to improve the speech quality of separated signals from an observed mix- ture. The key idea is to derive a mixture estimator based on sinusoidal parameters. The proposed estimator is aimed at finding...... the proposed method over other methods are confirmed by employing perceptual evaluation of speech quality (PESQ) as an objective measure and a MUSHRA listening test as a subjective evaluation for both speaker-dependent and gender-dependent scenarios....

  11. Span length and information rate optimisation in optical transmission systems using single-channel digital backpropagation.

    Science.gov (United States)

    Karanov, Boris; Xu, Tianhua; Shevchenko, Nikita A; Lavery, Domaniç; Killey, Robert I; Bayvel, Polina

    2017-10-16

    The optimisation of span length when designing optical communication systems is important from both performance and cost perspectives. In this paper, the optimisation of inter-amplifier spacing and the potential increase of span length at fixed information rates in optical communication systems with practically feasible nonlinearity compensation schemes have been investigated. It is found that in DP-16QAM, DP-64QAM and DP-256QAM systems with practical transceiver noise limitations, single-channel digital backpropagation can allow a 50% reduction in the number of amplifiers without sacrificing information rates compared to systems with optimal span lengths and linear compensation.

  12. A perspective on single-channel frequency-domain speech enhancement

    CERN Document Server

    Benesty, Jacob

    2010-01-01

    This book focuses on a class of single-channel noise reduction methods that are performed in the frequency domain via the short-time Fourier transform (STFT). The simplicity and relative effectiveness of this class of approaches make them the dominant choice in practical systems. Even though many popular algorithms have been proposed through more than four decades of continuous research, there are a number of critical areas where our understanding and capabilities still remain quite rudimentary, especially with respect to the relationship between noise reduction and speech distortion. All exis

  13. Creep in Al single crystal processed by equal-channel angular pressing

    Czech Academy of Sciences Publication Activity Database

    Král, Petr; Dvořák, Jiří; Šedá, Petra; Jäger, Aleš; Sklenička, Václav

    2012-01-01

    Roč. 31, č. 2 (2012), s. 138-144 ISSN 1606-5131. [Bulk nanostructured materials, BNM 2011. Ufa, 23.08.2011-26.08.2011] R&D Projects: GA AV ČR KAN300100801; GA ČR GPP108/10/P469 Institutional research plan: CEZ:AV0Z20410507; CEZ:AV0Z10100520 Keywords : equal-channel angular pressing * single crystal * creep behaviour Subject RIV: JJ - Other Materials; BM - Solid Matter Physics ; Magnetism (FZU-D) Impact factor: 1.017, year: 2012

  14. A single conserved basic residue in the potassium channel filter region controls KCNQ1 insensitivity toward scorpion toxins.

    Science.gov (United States)

    Chen, Zongyun; Hu, Youtian; Wang, Bin; Cao, Zhijian; Li, Wenxin; Wu, Yingliang

    2015-09-01

    Although many studies concerning the sensitivity mechanism of scorpion toxin-potassium channel interactions have been reported, few have explored the biochemical insensitivity mechanisms of potassium channel receptors toward natural scorpion toxin peptides, such as the KCNQ1 channel. Here, by sequence alignment analyses of the human KCNQ1 channel and scorpion potassium channel MmKv2, which is completely insensitive to scorpion toxins, we proposed that the insensitivity mechanism of KCNQ1 toward natural scorpion toxins might involve two functional regions, the turret and filter regions. Based on this observation, a series of KCNQ1 mutants were constructed to study molecular mechanisms of the KCNQ1 channel insensitivity toward natural scorpion toxins. Electrophysiological studies of chimera channels showed that the channel filter region controls KCNQ1 insensitivity toward the classical scorpion toxin ChTX. Interestingly, further residue mutant experiments showed that a single basic residue in the filter region determined the insensitivity of KCNQ1 channels toward scorpion toxins. Our present work showed that amino acid residue diversification at common sites controls the sensitivity and insensitivity of potassium channels toward scorpion toxins. The unique insensitivity mechanism of KCNQ1 toward natural scorpion toxins will accelerate the rational design of potent peptide inhibitors toward this channel.

  15. Re-Meandering of Lowland Streams

    DEFF Research Database (Denmark)

    Pedersen, Morten Lauge; Kristensen, Klaus Kevin; Friberg, Nikolai

    2014-01-01

    We evaluated the restoration of physical habitats and its influence on macroinvertebrate community structure in 18 Danish lowland streams comprising six restored streams, six streams with little physical alteration and six channelized streams. We hypothesized that physical habitats and macroinver...

  16. Changes in ion channel geometry resolved to sub-ångström precision via single molecule mass spectrometry

    Science.gov (United States)

    Robertson, Joseph W. F.; Kasianowicz, John J.; Reiner, Joseph E.

    2010-11-01

    The ion channel formed by Staphylococcus aureus alpha-hemolysin switches between multiple open conducting states. We describe a method for precisely estimating the changes in the ion channel geometry that correspond to these different states. Experimentally, we observed that the permeability of a single channel to differently sized poly(ethylene glycol) molecules depends on the magnitude of the open state conductance. A simple theory is proposed for determining changes in channel length of 4.2% and in cross-sectional area of - 0.4%.

  17. A Joint Approach for Single-Channel Speaker Identification and Speech Separation

    DEFF Research Database (Denmark)

    Mowlaee, Pejman; Saeidi, Rahim; Christensen, Mads Græsbøll

    2012-01-01

    a sinusoidal model-based algorithm. The speech separation algorithm consists of a double-talk/single-talk detector followed by a minimum mean square error estimator of sinusoidal parameters for finding optimal codevectors from pre-trained speaker codebooks. In evaluating the proposed system, we start from......In this paper, we present a novel system for joint speaker identification and speech separation. For speaker identification a single-channel speaker identification algorithm is proposed which provides an estimate of signal-to-signal ratio (SSR) as a by-product. For speech separation, we propose...... a situation where we have prior information of codebook indices, speaker identities and SSR-level, and then, by relaxing these assumptions one by one, we demonstrate the efficiency of the proposed fully blind system. In contrast to previous studies that mostly focus on automatic speech recognition (ASR...

  18. Simulating single-event burnout of n-channel power MOSFET's

    International Nuclear Information System (INIS)

    Johnson, G.H.; Hohl, J.H.; Schrimpf, R.D.; Galloway, K.F.

    1993-01-01

    Heavy ions are ubiquitous in a space environment. Single-event burnout of power MOSFET's is a sudden catastrophic failure mechanism that is initiated by the passage of a heavy ion through the device structure. The passage of the heavy ion generates a current filament that locally turns on a parasitic n-p-n transistor inherent to the power MOSFET. Subsequent high currents and high voltage in the device induce second breakdown of the parasitic bipolar transistor and hence meltdown of the device. This paper presents a model that can be used for simulating the burnout mechanism in order to gain insight into the significant device parameters that most influence the single-event burnout susceptibility of n-channel power MOSFET's

  19. Spontaneous formation of structurally diverse membrane channel architectures from a single antimicrobial peptide

    Science.gov (United States)

    Wang, Yukun; Chen, Charles H.; Hu, Dan; Ulmschneider, Martin B.; Ulmschneider, Jakob P.

    2016-11-01

    Many antimicrobial peptides (AMPs) selectively target and form pores in microbial membranes. However, the mechanisms of membrane targeting, pore formation and function remain elusive. Here we report an experimentally guided unbiased simulation methodology that yields the mechanism of spontaneous pore assembly for the AMP maculatin at atomic resolution. Rather than a single pore, maculatin forms an ensemble of structurally diverse temporarily functional low-oligomeric pores, which mimic integral membrane protein channels in structure. These pores continuously form and dissociate in the membrane. Membrane permeabilization is dominated by hexa-, hepta- and octamers, which conduct water, ions and small dyes. Pores form by consecutive addition of individual helices to a transmembrane helix or helix bundle, in contrast to current poration models. The diversity of the pore architectures--formed by a single sequence--may be a key feature in preventing bacterial resistance and could explain why sequence-function relationships in AMPs remain elusive.

  20. Multiple flow profiles for two-phase flow in single microfluidic channels through site-selective channel coating.

    Science.gov (United States)

    Logtenberg, Hella; Lopez-Martinez, Maria J; Feringa, Ben L; Browne, Wesley R; Verpoorte, Elisabeth

    2011-06-21

    An approach to control two-phase flow systems in a poly(dimethylsiloxane) (PDMS) microfluidic device using spatially selective surface modification is demonstrated. Side-by-side flows of ethanol : water solutions containing different polymers are used to selectively modify both sides of a channel by laminar flow patterning. Introduction of air pockets during modification allows for control over the length of the channel section that is modified. This approach makes it possible to achieve slug flow and side-by-side flow of water : 1-octanol simultaneously within the same PDMS channel, without the need of additional structural elements. A key finding is that conditioning of the PDMS channels with 1-octanol before polymer deposition is crucial to achieving stable side-by-side flows.

  1. Single-channel color image encryption based on iterative fractional Fourier transform and chaos

    Science.gov (United States)

    Sui, Liansheng; Gao, Bo

    2013-06-01

    A single-channel color image encryption is proposed based on iterative fractional Fourier transform and two-coupled logistic map. Firstly, a gray scale image is constituted with three channels of the color image, and permuted by a sequence of chaotic pairs which is generated by two-coupled logistic map. Firstly, the permutation image is decomposed into three components again. Secondly, the first two components are encrypted into a single one based on iterative fractional Fourier transform. Similarly, the interim image and third component are encrypted into the final gray scale ciphertext with stationary white noise distribution, which has camouflage property to some extent. In the process of encryption and description, chaotic permutation makes the resulting image nonlinear and disorder both in spatial domain and frequency domain, and the proposed iterative fractional Fourier transform algorithm has faster convergent speed. Additionally, the encryption scheme enlarges the key space of the cryptosystem. Simulation results and security analysis verify the feasibility and effectiveness of this method.

  2. Optical properties of 0.4-nm single-wall carbon nanotubes aligned in channels of AlPO4-5 single crystals

    NARCIS (Netherlands)

    Li, ZM; Liu, HJ; Ye, JT; Chan, CT; Tang, ZK

    Single-walled carbon nanotubes (SWNTs) of 0.4 nm in diameter are produced inside channels of microporous zeolite single crystals. Three possible structures: (5,0), (4,2), and (3,3) contribute to three bands at 1.37, 2.1, and 3.1 eV in optical absorption spectra. The direct correspondence between

  3. Lateral Dispersion of Pollutants in a Very Stable Atmosphere - The Effect of Meandering

    DEFF Research Database (Denmark)

    Kristensen, Leif; Jensen, Niels Otto; Lundtang Petersen, Erik

    1981-01-01

    A model based on single particle diffusion is introduced to account for the effect of “meandering” on lateral plume dispersion in a very stable atmosphere. It is assumed that small scale atmospheric turbulence is absent, so that only large horizontal eddies are effective. A formula for the lateral....... Meteorological data from Risø and the small island Sprogø have been analysed in order to identify all situations in which the atmosphere is so stable that small scale turbulence cannot exist. The purpose is to see in how many of these situations meandering is also absent. The results show that, as a rule...

  4. DFT-based channel estimation and noise variance estimation techniques for single-carrier FDMA

    OpenAIRE

    Huang, G; Nix, AR; Armour, SMD

    2010-01-01

    Practical frequency domain equalization (FDE) systems generally require knowledge of the channel and the noise variance to equalize the received signal in a frequency-selective fading channel. Accurate channel estimate and noise variance estimate are thus desirable to improve receiver performance. In this paper we investigate the performance of the denoise channel estimator and the approximate linear minimum mean square error (A-LMMSE) channel estimator with channel power delay profile (PDP) ...

  5. The formation and maintenance of single-thread tie channels entering floodplain lakes: observations from three diverse river systems

    Energy Technology Data Exchange (ETDEWEB)

    Rowland, Joel C [Los Alamos National Laboratory; Dietrich, William E [UC BERKELEY; Day, Geoff [NEWCREST MINING; Parker, Gary [UNIV OF ILLINOIS

    2009-01-01

    Tie channels connect rivers to floodplain lakes on many lowland rivers and thereby play a central role in floodplain sedimentology and ecology, yet they are generally unrecognized and little studied. here we report the results of field studies focused on tie channel origin and morphodynamics in three contrasting systems: the Middle Fly River, Papua New Guinea, the Lower Mississippi River, and Birch Creek in Alaska. Across these river systems, tie channels vary by an order of magnitude in size but exhibit the same characteristic morphology and appear to develop and evolve by a similar set of processes. In all three systems, the channels are characterized by a narrow, leveed single-thread morphology with maximum width approximately one tenth the width of the mainstem river. The channels typically have a V shaped cross-section, unlike most fluvial channels. These channels develop as lakes become isolated from the river by sedimentation. Narrowing of the connection between river and lake causes a sediment-laden jet to develop. Levees develop along the margins of the jet leading to channel emergence and eventual levee aggradation to the height of the mainstem levees. Bi-directional flow in these channels is common. Outflows from the lake scour sediment and prevent channel blockage. We propose that channel geometry and size are then controlled by a dynamic balance between channel narrowing by suspended sediment deposition and incision and widening by mass failure of banks during outflows. Tie channels are laterally stable and may convey flow for hundreds to a few thousand of years.

  6. On the prediction of single-phase forced convection heat transfer in narrow rectangular channels

    International Nuclear Information System (INIS)

    Ghione, Alberto; Noel, Brigitte; Vinai, Paolo; Demazière, Christophe

    2014-01-01

    In this paper, selected heat transfer correlations for single-phase forced convection are assessed for the case of narrow rectangular channels. The work is of interest in the thermal-hydraulic analysis of the Jules Horowitz Reactor (JHR), which is a research reactor under construction at CEA-Cadarache (France). In order to evaluate the validity of the correlations, about 300 tests from the SULTAN-JHR database were used. The SULTAN-JHR program was carried out at CEA-Grenoble and it includes different kinds of tests for two different vertical rectangular channels with height of 600 mm and gap of 1.51 and 2.16 mm. The experimental conditions range between 2 - 9 bar for the pressure; 0.5 - 18 m/s for the coolant velocity and 0.5 - 7.5 MW/m 2 for the heat flux (whose axial distribution is uniform). Forty-two thermocouples and eight pressure taps were placed at several axial locations, measuring wall temperature and pressure respectively. The analysis focused on turbulent flow with Reynolds numbers between 5.5 x 10 3 - 2.4 x 10 5 and Prandtl numbers between 1.5 - 6. It was shown that standard correlations as the Dittus-Boelter and Seider-Tate significantly under-estimate the heat transfer coefficient, especially at high Reynolds number. Other correlations specifically designed for narrow rectangular channels were also taken into account and compared. The correlation of Popov-Petukhov in the form suggested by Siman-Tov still under-estimates the heat transfer coefficient, even if slight improvements could be seen. A better agreement for the tests with gap equal to 2.16 mm could be found with the correlation of Ma and the one of Liang. However the heat transfer coefficient when the gap is equal to 1.51 mm could not be predicted accurately. Furthermore these correlations were based on data at low Reynolds numbers (up to 13000) and low heat flux, so the use of them for SULTAN-JHR may be questionable. According to the authors’ knowledge, existing models of heat transfer

  7. Morphology and Dynamics of Channels in the Coastal Zone: A Review

    Science.gov (United States)

    Dalrymple, R.; Ichaso, A.

    2011-12-01

    Channels in the coastal zone respond to water fluxes with two very different flow patterns and periodicities: unidirectional fluvial discharge which varies stochastically on time periods ranging from annual to decadal (or even longer); and bidirectional tidal flux which varies in a very regular manner on periods ranging from semi-diurnal to annual and even longer, but with most of the energy concentrated at short periods of hours to days. Maximum shear stresses for river currents typically occur when water depths are greatest, whereas those for tidal currents are greatest at depths less than bankfull. The relative importance of these two processes varies seasonally and over longer time periods. When averaged over periods of many years, this ratio appears to exert a first-order control on the morphology and dynamics of coastal-zone channels. This ratio varies along the length of individual channels through the fluvial-marine transition, between laterally adjacent channels because of differences in fluvial input, and between systems because of variations in runoff and tidal prism. The parts of channels with a tidal dominance tend to have a net landward movement of bed material, whereas the parts of channels that are river-dominated have a net seaward transport of bed material. Within 'estuaries' (i.e., transgressive coastal systems), which have unfilled accommodation because of relative sea-level rise, the bedload convergence that lies between the areas of seaward and landward bed-material transport lies landward of the coast. By contrast, channels such as active delta distributaries are river-dominated along their entire length and have expelled the bedload convergence during the transition from an estuarine phase. Within a single coastal system, channels that are more strongly fluvially dominated show less seaward flaring (i.e., a less pronounced funnel-shaped geometry) than adjacent channels with less fluvial influence. Because of the landward narrowing, most

  8. Analyses of Short Channel Effects of Single-Gate and Double-Gate Graphene Nanoribbon Field Effect Transistors

    Directory of Open Access Journals (Sweden)

    Hojjatollah Sarvari

    2016-01-01

    Full Text Available Short channel effects of single-gate and double-gate graphene nanoribbon field effect transistors (GNRFETs are studied based on the atomistic pz orbital model for the Hamiltonian of graphene nanoribbon using the nonequilibrium Green’s function formalism. A tight-binding Hamiltonian with an atomistic pz orbital basis set is used to describe the atomistic details in the channel of the GNRFETs. We have investigated the vital short channel effect parameters such as Ion and Ioff, the threshold voltage, the subthreshold swing, and the drain induced barrier lowering versus the channel length and oxide thickness of the GNRFETs in detail. The gate capacitance and the transconductance of both devices are also computed in order to calculate the intrinsic cut-off frequency and switching delay of GNRFETs. Furthermore, the effects of doping of the channel on the threshold voltage and the frequency response of the double-gate GNRFET are discussed. We have shown that the single-gate GNRFET suffers more from short channel effects if compared with those of the double-gate structure; however, both devices have nearly the same cut-off frequency in the range of terahertz. This work provides a collection of data comparing different features of short channel effects of the single gate with those of the double gate GNRFETs. The results give a very good insight into the devices and are very useful for their digital applications.

  9. Multi-Channel 40 Gbit/s NRZ-DPSK Demodulation Using a Single Silicon Microring Resonator

    DEFF Research Database (Denmark)

    Ding, Yunhong; Xu, Jing; Peucheret, Christophe

    2011-01-01

    We comprehensively analyze the demodulation of wavelength division multiplexed (WDM) non return-to-zero differential phase-shift keying (NRZ-DPSK) signals by a single microring resonator. Simultaneous demodulation of multiple 40 Gbit/s WDM NRZ-DPSK channels is demonstrated using a single silicon...

  10. Assessment of the effects of regional channel stability and sediment transport on roadway hydraulic structures : final report.

    Science.gov (United States)

    2014-06-01

    Rivers and streams evolve all the time. As a result, no stream channel is absolutely stable. Channels evolve at various speeds both vertically (degradation/aggradation) and horizontally (meander : migration). They also respond to man-made changes ran...

  11. Numerical Estimation of the Outer Bank Resistance Characteristics in AN Evolving Meandering River

    Science.gov (United States)

    Wang, D.; Konsoer, K. M.; Rhoads, B. L.; Garcia, M. H.; Best, J.

    2017-12-01

    Few studies have examined the three-dimensional flow structure and its interaction with bed morphology within elongate loops of large meandering rivers. The present study uses a numerical model to simulate the flow pattern and sediment transport, especially the flow close to the outer-bank, at two elongate meandering loops in Wabash River, USA. The numerical grid for the model is based on a combination of airborne LIDAR data on floodplains and the multibeam data within the river channel. A Finite Element Method (FEM) is used to solve the non-hydrostatic RANS equation using a K-epsilon turbulence closure scheme. High-resolution topographic data allows detailed numerical simulation of flow patterns along the outer bank and model calibration involves comparing simulated velocities to ADCP measurements at 41 cross sections near this bank. Results indicate that flow along the outer bank is strongly influenced by large resistance elements, including woody debris, large erosional scallops within the bank face, and outcropping bedrock. In general, patterns of bank migration conform with zones of high near-bank velocity and shear stress. Using the existing model, different virtual events can be simulated to explore the impacts of different resistance characteristics on patterns of flow, sediment transport, and bank erosion.

  12. Bank pull or bar push: What drives scroll-bar formation in meandering rivers?

    NARCIS (Netherlands)

    van de Lageweg, W. I.; van Dijk, W. M.; Baar, A. W.; Rutten, J.; Kleinhans, M. G.

    2014-01-01

    One of the most striking features of meandering rivers are quasi-regular ridges of the point bar, evidence of a pulsed lateral migration of meander bends. Scroll bars formed on the inner bend are preserved on the point-bar surface as a series of ridges as meanders migrate, and in the subsurface of

  13. Response matrix method and its application to SCWR single channel stability analysis

    International Nuclear Information System (INIS)

    Zhao, Jiyun; Tseng, K.J.; Tso, C.P.

    2011-01-01

    To simulate the reactor system dynamic features during density wave oscillations (DWO), both the non-linear method and the linear method can be used. Although some transient information is lost through model linearization, the high computational efficiency and relatively accurate results make the linear analysis methodology attractive, especially for prediction of the onset of instability. In the linear stability analysis, the system models are simplified through linearization of the complex non-linear differential equations, and then, the linear differential equations are generally solved in the frequency domain through Laplace transformation. In this paper, a system response matrix method was introduced by directly solving the differential equations in the time domain. By using a system response matrix method, the complicated transfer function derivation, which must be done in the frequency domain method, can be avoided. Using the response matrix method, a model was developed and applied to the single channel or parallel channel type instability analyses of the typical proposed SCWR design. The sensitivity of the decay ratio (DR) to the axial mesh size was analyzed and it was found that the DR is not sensitive to mesh size once sufficient number of axial nodes is applied. To demonstrate the effects of the inlet orificing to the stability feature for the supercritical condition, the sensitivity of the stability to inlet orifice coefficient was conducted for hot channel. It is clearly shown that a higher inlet orifice coefficient will make the system more stable. The susceptibility of stability to operating parameters such as mass flow rate, power and system pressure was also performed. And the measure to improve the SCWR stability sensitivity to operating parameters was investigated. It was found that the SCWR stability sensitivity feature can be improved by carefully managing the inlet orifices and choosing proper operating parameters. (author)

  14. Terahertz light-emitting graphene-channel transistor toward single-mode lasing

    Directory of Open Access Journals (Sweden)

    Yadav Deepika

    2018-03-01

    Full Text Available A distributed feedback dual-gate graphene-channel field-effect transistor (DFB-DG-GFET was fabricated as a current-injection terahertz (THz light-emitting laser transistor. We observed a broadband emission in a 1–7.6-THz range with a maximum radiation power of ~10 μW as well as a single-mode emission at 5.2 THz with a radiation power of ~0.1 μW both at 100 K when the carrier injection stays between the lower cutoff and upper cutoff threshold levels. The device also exhibited peculiar nonlinear threshold-like behavior with respect to the current-injection level. The LED-like broadband emission is interpreted as an amplified spontaneous THz emission being transcended to a single-mode lasing. Design constraints on waveguide structures for better THz photon field confinement with higher gain overlapping as well as DFB cavity structures with higher Q factors are also addressed towards intense, single-mode continuous wave THz lasing at room temperature.

  15. Simple non-Markovian microscopic models for the depolarizing channel of a single qubit

    International Nuclear Information System (INIS)

    Fonseca Romero, K M; Lo Franco, R

    2012-01-01

    The archetypal one-qubit noisy channels - depolarizing, phase-damping and amplitude-damping channels - describe both Markovian and non-Markovian evolution. Simple microscopic models for the depolarizing channel, both classical and quantum, are considered. Microscopic models that describe phase-damping and amplitude-damping channels are briefly reviewed.

  16. Single intravenous and oral dose pharmacokinetics of florfenicol in the channel catfish (Ictalurus punctatus).

    Science.gov (United States)

    Gaunt, P S; Langston, C; Wrzesinski, C; Gao, D; Adams, P; Crouch, L; Sweeney, D; Endris, R

    2012-10-01

    Plasma distribution and elimination of florfenicol in channel catfish were investigated after a single dose (10 mg/kg) of intravenous (i.v.) or oral administration in freshwater at a mean water temperature of 25.4 °C. Florfenicol concentrations in plasma were analyzed by means of liquid chromatography with MS/MS detection. After i.v. florfenicol injection, the terminal half-life (t(1/2)), volume of distribution at steady state (V(ss)), and central volume of distribution (V(c)) were 8.25 h, 0.9 and 0.381 L/kg, respectively. After oral administration of florfenicol, the terminal t(1/2), C(max), T(max), and oral bioavailability (F) were 9.11 h, 7.6 μg/mL, 9.2 h, and 1.09, respectively. There was a lag absorption time of 1.67 h in oral dosing. Results from these studies support that 10 mg florfenicol/kg body weight in channel catfish is an efficacious dosage following oral administration. © 2011 Blackwell Publishing Ltd.

  17. Single-channel color image encryption using phase retrieve algorithm in fractional Fourier domain

    Science.gov (United States)

    Sui, Liansheng; Xin, Meiting; Tian, Ailing; Jin, Haiyan

    2013-12-01

    A single-channel color image encryption is proposed based on a phase retrieve algorithm and a two-coupled logistic map. Firstly, a gray scale image is constituted with three channels of the color image, and then permuted by a sequence of chaotic pairs generated by the two-coupled logistic map. Secondly, the permutation image is decomposed into three new components, where each component is encoded into a phase-only function in the fractional Fourier domain with a phase retrieve algorithm that is proposed based on the iterative fractional Fourier transform. Finally, an interim image is formed by the combination of these phase-only functions and encrypted into the final gray scale ciphertext with stationary white noise distribution by using chaotic diffusion, which has camouflage property to some extent. In the process of encryption and decryption, chaotic permutation and diffusion makes the resultant image nonlinear and disorder both in spatial domain and frequency domain, and the proposed phase iterative algorithm has faster convergent speed. Additionally, the encryption scheme enlarges the key space of the cryptosystem. Simulation results and security analysis verify the feasibility and effectiveness of this method.

  18. Multiphysics Modeling of a Single Channel in a Nuclear Thermal Propulsion Grooved Ring Fuel Element

    Science.gov (United States)

    Kim, Tony; Emrich, William J., Jr.; Barkett, Laura A.; Mathias, Adam D.; Cassibry, Jason T.

    2013-01-01

    In the past, fuel rods have been used in nuclear propulsion applications. A new fuel element concept that reduces weight and increases efficiency uses a stack of grooved discs. Each fuel element is a flat disc with a hole on the interior and grooves across the top. Many grooved ring fuel elements for use in nuclear thermal propulsion systems have been modeled, and a single flow channel for each design has been analyzed. For increased efficiency, a fuel element with a higher surface-area-to-volume ratio is ideal. When grooves are shallower, i.e., they have a lower surface area, the results show that the exit temperature is higher. By coupling the physics of turbulence with those of heat transfer, the effects on the cooler gas flowing through the grooves of the thermally excited solid can be predicted. Parametric studies were done to show how a pressure drop across the axial length of the channels will affect the exit temperatures of the gas. Geometric optimization was done to show the behaviors that result from the manipulation of various parameters. Temperature profiles of the solid and gas showed that more structural optimization is needed to produce the desired results. Keywords: Nuclear Thermal Propulsion, Fuel Element, Heat Transfer, Computational Fluid Dynamics, Coupled Physics Computations, Finite Element Analysis

  19. Enhanced sediment loading facilitates point bar growth and accelerates bank erosion along a modelled meander bend on the Sacramento River, USA

    Science.gov (United States)

    Ahmed, J.; Constantine, J. A.; Hales, T. C.

    2017-12-01

    Meandering channels provide a conduit through which sediment and water is routed from the uplands to the sea. Alluvial material is periodically stored and transported through the channel network as permitted by the prevailing hydrologic conditions. The lowlands are typically characterised by accumulations of sediment attached to the inner banks of meander bends (point bars). These bedforms have been identified as important for facilitating a link between in-stream sediment supplies and channel dynamism. A 2D curvilinear hydrodynamic model (MIKE 21C) was used to perform a number of experiments in which the sediment load was adjusted to investigate how changes in alluvial material fluxes affect the development of point bars and the resultant patterns of bank erosion. A doubling of the sediment load caused a longitudinal increase in the bar in the upstream direction and caused a coeval doubling of the transverse channel slope at the meander apex. The upstream growth of the point bar was accompanied by an increase in length over which lateral migration took place at the outer bank. The magnitude of outer bank erosion was 9-times greater for the high-sediment simulation. These results suggest that enhanced sediment loads (potentially the result of changes in land use or climate) can trigger greater rates of bank erosion and channel change through the sequestration of alluvial material on point bars, which encourage high-velocity fluid deflection towards the outer bank of the meander. This controls riparian habitat development and exchanges of sediment and nutrients across the channel-floodplain interface.

  20. Multiple flow profiles for two-phase flow in single microfluidic channels through site-selective channel coating

    NARCIS (Netherlands)

    Logtenberg, Hella; Lopez-Martinez, Maria J.; Feringa, Ben L.; Browne, Wesley R.; Verpoorte, Elisabeth

    2011-01-01

    An approach to control two-phase flow systems in a poly(dimethylsiloxane) (PDMS) microfluidic device using spatially selective surface modification is demonstrated. Side-by-side flows of ethanol : water solutions containing different polymers are used to selectively modify both sides of a channel by

  1. Single-channel in-ear-EEG detects the focus of auditory attention to concurrent tone streams and mixed speech

    Science.gov (United States)

    Fiedler, Lorenz; Wöstmann, Malte; Graversen, Carina; Brandmeyer, Alex; Lunner, Thomas; Obleser, Jonas

    2017-06-01

    Objective. Conventional, multi-channel scalp electroencephalography (EEG) allows the identification of the attended speaker in concurrent-listening (‘cocktail party’) scenarios. This implies that EEG might provide valuable information to complement hearing aids with some form of EEG and to install a level of neuro-feedback. Approach. To investigate whether a listener’s attentional focus can be detected from single-channel hearing-aid-compatible EEG configurations, we recorded EEG from three electrodes inside the ear canal (‘in-Ear-EEG’) and additionally from 64 electrodes on the scalp. In two different, concurrent listening tasks, participants (n  =  7) were fitted with individualized in-Ear-EEG pieces and were either asked to attend to one of two dichotically-presented, concurrent tone streams or to one of two diotically-presented, concurrent audiobooks. A forward encoding model was trained to predict the EEG response at single EEG channels. Main results. Each individual participants’ attentional focus could be detected from single-channel EEG response recorded from short-distance configurations consisting only of a single in-Ear-EEG electrode and an adjacent scalp-EEG electrode. The differences in neural responses to attended and ignored stimuli were consistent in morphology (i.e. polarity and latency of components) across subjects. Significance. In sum, our findings show that the EEG response from a single-channel, hearing-aid-compatible configuration provides valuable information to identify a listener’s focus of attention.

  2. Hydrodynamic processes in sharp meander bends and their morphological implications

    NARCIS (Netherlands)

    Blanckaert, K.

    2011-01-01

    The migration rate of sharp meander bends exhibits large variance and indicates that some sharply curved bends tend to stabilize. These observations remain unexplained. This paper examines three hydrodynamic processes in sharp bends with fixed banks and discusses their morphological implications:

  3. Elucidating distinct ion channel populations on the surface of hippocampal neurons via single-particle tracking recurrence analysis

    Science.gov (United States)

    Sikora, Grzegorz; Wyłomańska, Agnieszka; Gajda, Janusz; Solé, Laura; Akin, Elizabeth J.; Tamkun, Michael M.; Krapf, Diego

    2017-12-01

    Protein and lipid nanodomains are prevalent on the surface of mammalian cells. In particular, it has been recently recognized that ion channels assemble into surface nanoclusters in the soma of cultured neurons. However, the interactions of these molecules with surface nanodomains display a considerable degree of heterogeneity. Here, we investigate this heterogeneity and develop statistical tools based on the recurrence of individual trajectories to identify subpopulations within ion channels in the neuronal surface. We specifically study the dynamics of the K+ channel Kv1.4 and the Na+ channel Nav1.6 on the surface of cultured hippocampal neurons at the single-molecule level. We find that both these molecules are expressed in two different forms with distinct kinetics with regards to surface interactions, emphasizing the complex proteomic landscape of the neuronal surface. Further, the tools presented in this work provide new methods for the analysis of membrane nanodomains, transient confinement, and identification of populations within single-particle trajectories.

  4. Re-Meandering of Lowland Streams

    DEFF Research Database (Denmark)

    Pedersen, Morten Lauge; Kristensen, Klaus Kevin; Friberg, Nikolai

    2014-01-01

    We evaluated the restoration of physical habitats and its influence on macroinvertebrate community structure in 18 Danish lowland streams comprising six restored streams, six streams with little physical alteration and six channelized streams. We hypothesized that physical habitats...... and macroinvertebrate communities of restored streams would resemble those of natural streams, while those of the channelized streams would differ from both restored and near-natural streams. Physical habitats were surveyed for substrate composition, depth, width and current velocity. Macroinvertebrates were sampled...... along 100 m reaches in each stream, in edge habitats and in riffle/run habitats located in the center of the stream. Restoration significantly altered the physical conditions and affected the interactions between stream habitat heterogeneity and macroinvertebrate diversity. The substrate in the restored...

  5. 12-Channel Peltier array temperature control unit for single molecule enzymology studies using capillary electrophoresis.

    Science.gov (United States)

    Craig, Douglas B; Reinfelds, Gundars; Henderson, Anna

    2014-08-01

    Capillary electrophoresis has been used to demonstrate that individual molecules of a given enzyme support different catalytic rates. In order to determine how rate varies with temperature, and determine activation energies for individual β-galactosidase molecules, a 12-channel Peltier array temperature control device was constructed where the temperature of each cell was separately controlled. This array was used to control the temperature of the central 30 cm of a 50 cm long capillary, producing a temperature gradient along its length. Continuous flow single β-galactosidase molecule assays were performed allowing measurement of the catalytic rates at different temperatures. Arrhenius plots were produced and the distribution of activation energies for individual β-galactosidase molecules was found to be 56 ± 10 kJ/mol with a range of 34-72 kJ/mol. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Subjective and Objective Quality Assessment of Single-Channel Speech Separation Algorithms

    DEFF Research Database (Denmark)

    Mowlaee, Pejman; Saeidi, Rahim; Christensen, Mads Græsbøll

    2012-01-01

    Previous studies on performance evaluation of single-channel speech separation (SCSS) algorithms mostly focused on automatic speech recognition (ASR) accuracy as their performance measure. Assessing the separated signals by different metrics other than this has the benefit that the results...... are expected to carry on to other applications beyond ASR. In this paper, in addition to conventional speech quality metrics (PESQ and SNRloss), we also evaluate the separation systems output using different source separation metrics: blind source separation evaluation (BSS EVAL) and perceptual evaluation...... that PESQ and PEASS quality metrics predict well the subjective quality of separated signals obtained by the separation systems. From the results it is observed that the short-time objective intelligibility (STOI) measure predict the speech intelligibility results....

  7. Digital single-channel seismic-reflection data from western Santa Monica basin

    Science.gov (United States)

    Normark, William R.; Piper, David J.W.; Sliter, Ray W.; Triezenberg, Peter; Gutmacher, Christina E.

    2006-01-01

    During a collaborative project in 1992, Geological Survey of Canada and United States Geological Survey scientists obtained about 850 line-km of high-quality single-channel boomer and sleeve-gun seismic-reflection profiles across Hueneme, Mugu and Dume submarine fans, Santa Monica Basin, off southern California. The goals of this work were to better understand the processes that lead to the formation of sandy submarine fans and the role of sea-level changes in controlling fan development. This report includes a trackline map of the area surveyed, as well as images of the sleeve-gun profiles and the opportunity to download both images and digital data files (SEG-Y) of all the sleeve-gun profiles.

  8. On nonlinearly-induced noise in single-channel optical links with digital backpropagation.

    Science.gov (United States)

    Beygi, Lotfollah; Irukulapati, Naga V; Agrell, Erik; Johannisson, Pontus; Karlsson, Magnus; Wymeersch, Henk; Serena, Paolo; Bononi, Alberto

    2013-11-04

    In this paper, we investigate the performance limits of electronic chromatic dispersion compensation (EDC) and digital backpropagation (DBP) for a single-channel non-dispersion-managed fiber-optical link. A known analytical method to derive the performance of the system with EDC is extended to derive a first-order approximation for the performance of the system with DBP. In contrast to the cubic growth of the variance of the nonlinear noise-like interference, often called nonlinear noise, with input power for EDC, a quadratic growth is observed with DBP using this approximation. Finally, we provide numerical results to verify the accuracy of the proposed approach and compare it with existing analytical models.

  9. SYN3D: a single-channel, spatial flux synthesis code for diffusion theory calculations

    Energy Technology Data Exchange (ETDEWEB)

    Adams, C. H.

    1976-07-01

    This report is a user's manual for SYN3D, a computer code which uses single-channel, spatial flux synthesis to calculate approximate solutions to two- and three-dimensional, finite-difference, multigroup neutron diffusion theory equations. SYN3D is designed to run in conjunction with any one of several one- and two-dimensional, finite-difference codes (required to generate the synthesis expansion functions) currently being used in the fast reactor community. The report describes the theory and equations, the use of the code, and the implementation on the IBM 370/195 and CDC 7600 of the version of SYN3D available through the Argonne Code Center.

  10. SYN3D: a single-channel, spatial flux synthesis code for diffusion theory calculations

    International Nuclear Information System (INIS)

    Adams, C.H.

    1976-07-01

    This report is a user's manual for SYN3D, a computer code which uses single-channel, spatial flux synthesis to calculate approximate solutions to two- and three-dimensional, finite-difference, multigroup neutron diffusion theory equations. SYN3D is designed to run in conjunction with any one of several one- and two-dimensional, finite-difference codes (required to generate the synthesis expansion functions) currently being used in the fast reactor community. The report describes the theory and equations, the use of the code, and the implementation on the IBM 370/195 and CDC 7600 of the version of SYN3D available through the Argonne Code Center

  11. Search for s-channel single top-quark production in pp collisions

    CERN Document Server

    Merola, Mario

    2015-01-01

    A search for single top-quark production in the s channel in proton-proton collisions at a centre-of-mass energy of 8 TeV by the CMS detector at the LHC is presented. Leptonic decay modes of the top quark with an electron or muon in the final state are considered. The signal is extracted by performing a maximum-likelihood fit to the distribution of a multivariate discriminant defined using Boosted Decision Trees to separate the expected signal contribution from the background processes. Data collected in 2012, corresponding to an integrated luminosity of 19.3 / fb, lead to an upper limit on the cross section times branching ratio of 11.5 pb at 95pct confidence level.

  12. Stochastic gravitational wave background from the single-degenerate channel of type Ia supernovae

    International Nuclear Information System (INIS)

    Falta, David; Fisher, Robert

    2011-01-01

    We demonstrate that the integrated gravitational wave signal of type Ia supernovae (SNe Ia) in the single-degenerate channel out to cosmological distances gives rise to a continuous background to spaceborne gravitational wave detectors, including the Big Bang Observer and Deci-Hertz Interferometer Gravitational wave Observatory planned missions. This gravitational wave background from SNe Ia acts as a noise background in the frequency range 0.1-10 Hz, which heretofore was thought to be relatively free from astrophysical sources apart from neutron-star and white-dwarf binaries, and therefore a key window in which to study primordial gravitational waves generated by inflation. While inflationary energy scales of > or approx. 10 16 GeV yield inflationary gravitational wave backgrounds in excess of our range of predicted backgrounds, for lower energy scales of ∼10 15 GeV, the inflationary gravitational wave background becomes comparable to the noise background from SNe Ia.

  13. Drowsiness detection for single channel EEG by DWT best m-term approximation

    Directory of Open Access Journals (Sweden)

    Tiago da Silveira

    Full Text Available Introduction In this paper we propose a promising new technique for drowsiness detection. It consists of applying the best m-term approximation on a single-channel electroencephalography (EEG signal preprocessed through a discrete wavelet transform. Methods In order to classify EEG epochs as awake or drowsy states, the most significant m terms from the wavelet expansion of an EEG signal are selected according to the magnitude of their coefficients related to the alpha and beta rhythms. Results By using a simple thresholding strategy it provides hit rates comparable to those using more complex techniques. It was tested on a set of 6 hours and 50 minutes EEG drowsiness signals from PhysioNet Sleep Database yielding an overall sensitivity (TPR of 84.98% and 98.65% of precision (PPV. Conclusion The method has proved itself efficient at separating data from different brain rhythms, thus alleviating the requirement for complex post-processing classification algorithms.

  14. Study on single-channel signals of water Cherenkov detector array for the LHAASO project

    Energy Technology Data Exchange (ETDEWEB)

    Li, H.C., E-mail: lihuicai@ihep.ac.cn [University of Nankai, Tianjin 300071 (China); Yao, Z.G.; Chen, M.J. [Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); Yu, C.X. [University of Nankai, Tianjin 300071 (China); Zha, M.; Wu, H.R.; Gao, B.; Wang, X.J. [Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); Liu, J.Y.; Liao, W.Y. [University of Nankai, Tianjin 300071 (China); Huang, D.Z. [Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China)

    2017-05-11

    The Large High Altitude Air Shower Observatory (LHAASO) is planned to be built at Daocheng, Sichuan Province, China. The water Cherenkov detector array (WCDA), with an area of 78,000 m{sup 2} and capacity of 350,000 tons of purified water, is one of the major components of the LHAASO project. A 9-cell detector prototype array has been built at the Yangbajing site, Tibet, China to comprehensively understand the water Cherenkov technique and investigate the engineering issues of WCDA. In this paper, the rate and charge distribution of single-channel signals are evaluated using a full detail Monte Carlo simulation. The results are discussed and compared with the results obtained with prototype array.

  15. Volume reflection and channeling of ultrarelativistic protons in germanium bent single crystals

    Directory of Open Access Journals (Sweden)

    S. Bellucci

    2016-12-01

    Full Text Available The paper is devoted to the investigation of volume reflection and channeling processes of ultrarelativistic positive charged particles moving in germanium single crystals. We demonstrate that the choice of atomic potential on the basis of the Hartree-Fock method and the correct choice of the Debye temperature allow us to describe the above mentioned processes in a good agreement with the recent experiments. Moreover, the universal form of equations for volume reflection presented in the paper gives a true description of the process at a wide range of particle energies. Standing on this study we make predictions for the mean angle reflection (as a function of the bending radius of positive and negative particles for germanium (110 and (111 crystallographic planes.

  16. Multi-feature classifiers for burst detection in single EEG channels from preterm infants

    Science.gov (United States)

    Navarro, X.; Porée, F.; Kuchenbuch, M.; Chavez, M.; Beuchée, Alain; Carrault, G.

    2017-08-01

    Objective. The study of electroencephalographic (EEG) bursts in preterm infants provides valuable information about maturation or prognostication after perinatal asphyxia. Over the last two decades, a number of works proposed algorithms to automatically detect EEG bursts in preterm infants, but they were designed for populations under 35 weeks of post menstrual age (PMA). However, as the brain activity evolves rapidly during postnatal life, these solutions might be under-performing with increasing PMA. In this work we focused on preterm infants reaching term ages (PMA  ⩾36 weeks) using multi-feature classification on a single EEG channel. Approach. Five EEG burst detectors relying on different machine learning approaches were compared: logistic regression (LR), linear discriminant analysis (LDA), k-nearest neighbors (kNN), support vector machines (SVM) and thresholding (Th). Classifiers were trained by visually labeled EEG recordings from 14 very preterm infants (born after 28 weeks of gestation) with 36-41 weeks PMA. Main results. The most performing classifiers reached about 95% accuracy (kNN, SVM and LR) whereas Th obtained 84%. Compared to human-automatic agreements, LR provided the highest scores (Cohen’s kappa  =  0.71) using only three EEG features. Applying this classifier in an unlabeled database of 21 infants  ⩾36 weeks PMA, we found that long EEG bursts and short inter-burst periods are characteristic of infants with the highest PMA and weights. Significance. In view of these results, LR-based burst detection could be a suitable tool to study maturation in monitoring or portable devices using a single EEG channel.

  17. Cross-section measurement of single-top t-channel production at ATLAS

    International Nuclear Information System (INIS)

    Herrberg-Schubert, Ruth Hedwig Margarete

    2014-01-01

    This study presents the cross-section measurement of electroweak single-top quark production in the t-channel with a semi-leptonically decaying top quark. The study is based on 4.7 fb -1 of proton-proton collision data recorded with the ATLAS detector at the Large Hadron Collider in the year 2011. Selected events contain two highly energetic jets, one of which is identified as originating from a beauty quark, as well as a highly energetic electron or muon and transverse missing energy. The case of three and four jets is also considered but eventually discarded since their inclusion degrades the precision of the result. The event reconstruction is done with a chi-square-based kinematic fit using W boson and top quark mass constraints. The chi-square value in each event serves to classify the event as a signal-like or background-like process. The cross-section is extracted by performing a template-based maximum likelihood fit to the distribution that displays the best discriminatory power: This distribution is chosen such that the shape differences between signal and background with respect to the typical forward light jet kinematics of the t-channel are exploited. An observation of the single-top t-channel process with a significance of 5.7 σ is obtained, and the cross-section is measured to be 111 +29 -28 pb. Assuming vertical stroke V tb vertical stroke 2 >> vertical stroke V td vertical stroke 2 + vertical stroke V ts vertical stroke 2 as well as a (V-A), CP-conserving interaction, and allowing for the presence of anomalous couplings at the W-t-b vertex, the associated value of the CKM matrix element times an anomalous form factor is determined as vertical stroke V tb f L 1 vertical stroke =1.30 +0.13 -0.16 . The corresponding lower limit in the standard model scenario 0≤ vertical stroke V tb vertical stroke ≤1 amounts to 0.77 tb vertical stroke at 95% confidence level.

  18. Single-channel properties of a stretch-sensitive chloride channel in the human mast cell line HMC-1.

    Science.gov (United States)

    Wang, Lina; Ding, Guanghong; Gu, Quanbao; Schwarz, Wolfgang

    2010-04-01

    A stretch-activated (SA) Cl(-) channel in the plasma membrane of the human mast cell line HMC-1 was identified in outside-out patch-clamp experiments. SA currents, induced by pressure applied to the pipette, exhibited voltage dependence with strong outward rectification (55.1 pS at +100 mV and an about tenfold lower conductance at -100 mV). The probability of the SA channel being open (P (o)) also showed steep outward rectification and pressure dependence. The open-time distribution was fitted with three components with time constants of tau(1o) = 755.1 ms, tau(2o) = 166.4 ms, and tau(3o) = 16.5 ms at +60 mV. The closed-time distribution also required three components with time constants of tau(1c) = 661.6 ms, tau(2c) = 253.2 ms, and tau(3c) = 5.6 ms at +60 mV. Lowering extracellular Cl(-) concentration reduced the conductance, shifted the reversal potential toward chloride reversal potential, and decreased the P (o) at positive potentials. The SA Cl(-) currents were reversibly blocked by the chloride channel blocker 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS) but not by (Z)-1-(p-dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene (tamoxifen). Furthermore, in HMC-1 cells swelling due to osmotic stress, DIDS could inhibit the increase in intracellular [Ca(2+)] and degranulation. We conclude that in the HMC-1 cell line, the SA outward currents are mediated by Cl(-) influx. The SA Cl(-) channel might contribute to mast cell degranulation caused by mechanical stimuli or accelerate membrane fusion during the degranulation process.

  19. Photoionisation detection of single {sup 87}Rb-atoms using channel electron multipliers

    Energy Technology Data Exchange (ETDEWEB)

    Henkel, Florian Alexander

    2011-09-02

    Fast and efficient detection of single atoms is a universal requirement concerning modern experiments in atom physics, quantum optics, and precision spectroscopy. In particular for future quantum information and quantum communication technologies, the efficient readout of qubit states encoded in single atoms or ions is an elementary prerequisite. The rapid development in the field of quantum optics and atom optics in the recent years has enabled to prepare individual atoms as quantum memories or arrays of single atoms as qubit registers. With such systems, the implementation of quantum computation or quantum communication protocols seems feasible. This thesis describes a novel detection scheme which enables fast and efficient state analysis of single neutral atoms. The detection scheme is based on photoionisation and consists of two parts: the hyperfine-state selective photoionisation of single atoms and the registration of the generated photoion-electron pairs via two channel electron multipliers (CEMs). In this work, both parts were investigated in two separate experiments. For the first step, a photoionisation probability of p{sub ion}=0.991 within an ionisation time of t{sub ion}=386 ns is achieved for a single {sup 87}Rb-atom in an optical dipole trap. For the second part, a compact detection system for the ionisation fragments was developed consisting of two opposing CEM detectors. Measurements show that single neutral atoms can be detected via their ionisation fragments with a detection efficiency of {eta}{sub atom}=0.991 within a detection time of t{sub det}=415.5 ns. In a future combined setup, this will allow the state-selective readout of optically trapped, single neutral {sup 87}Rb-atoms via photoionisation detection with an estimated detection efficiency {eta}=0.982 and a detection time of t{sub tot} = 802 ns. Although initially developed for single {sup 87}Rb-atoms, the concept of photoionisation detection is in principle generally applicable to any

  20. 32-channel time-correlated-single-photon-counting system for high-throughput lifetime imaging.

    Science.gov (United States)

    Peronio, P; Labanca, I; Acconcia, G; Ruggeri, A; Lavdas, A A; Hicks, A A; Pramstaller, P P; Ghioni, M; Rech, I

    2017-08-01

    Time-Correlated Single Photon Counting (TCSPC) is a very efficient technique for measuring weak and fast optical signals, but it is mainly limited by the relatively "long" measurement time. Multichannel systems have been developed in recent years aiming to overcome this limitation by managing several detectors or TCSPC devices in parallel. Nevertheless, if we look at state-of-the-art systems, there is still a strong trade-off between the parallelism level and performance: the higher the number of channels, the poorer the performance. In 2013, we presented a complete and compact 32 × 1 TCSPC system, composed of an array of 32 single-photon avalanche diodes connected to 32 time-to-amplitude converters, which showed that it was possible to overcome the existing trade-off. In this paper, we present an evolution of the previous work that is conceived for high-throughput fluorescence lifetime imaging microscopy. This application can be addressed by the new system thanks to a centralized logic, fast data management and an interface to a microscope. The new conceived hardware structure is presented, as well as the firmware developed to manage the operation of the module. Finally, preliminary results, obtained from the practical application of the technology, are shown to validate the developed system.

  1. 32-channel time-correlated-single-photon-counting system for high-throughput lifetime imaging

    Science.gov (United States)

    Peronio, P.; Labanca, I.; Acconcia, G.; Ruggeri, A.; Lavdas, A. A.; Hicks, A. A.; Pramstaller, P. P.; Ghioni, M.; Rech, I.

    2017-08-01

    Time-Correlated Single Photon Counting (TCSPC) is a very efficient technique for measuring weak and fast optical signals, but it is mainly limited by the relatively "long" measurement time. Multichannel systems have been developed in recent years aiming to overcome this limitation by managing several detectors or TCSPC devices in parallel. Nevertheless, if we look at state-of-the-art systems, there is still a strong trade-off between the parallelism level and performance: the higher the number of channels, the poorer the performance. In 2013, we presented a complete and compact 32 × 1 TCSPC system, composed of an array of 32 single-photon avalanche diodes connected to 32 time-to-amplitude converters, which showed that it was possible to overcome the existing trade-off. In this paper, we present an evolution of the previous work that is conceived for high-throughput fluorescence lifetime imaging microscopy. This application can be addressed by the new system thanks to a centralized logic, fast data management and an interface to a microscope. The new conceived hardware structure is presented, as well as the firmware developed to manage the operation of the module. Finally, preliminary results, obtained from the practical application of the technology, are shown to validate the developed system.

  2. Performance evaluation of an automated single-channel sleep–wake detection algorithm

    Science.gov (United States)

    Kaplan, Richard F; Wang, Ying; Loparo, Kenneth A; Kelly, Monica R; Bootzin, Richard R

    2014-01-01

    Background A need exists, from both a clinical and a research standpoint, for objective sleep measurement systems that are both easy to use and can accurately assess sleep and wake. This study evaluates the output of an automated sleep–wake detection algorithm (Z-ALG) used in the Zmachine (a portable, single-channel, electroencephalographic [EEG] acquisition and analysis system) against laboratory polysomnography (PSG) using a consensus of expert visual scorers. Methods Overnight laboratory PSG studies from 99 subjects (52 females/47 males, 18–60 years, median age 32.7 years), including both normal sleepers and those with a variety of sleep disorders, were assessed. PSG data obtained from the differential mastoids (A1–A2) were assessed by Z-ALG, which determines sleep versus wake every 30 seconds using low-frequency, intermediate-frequency, and high-frequency and time domain EEG features. PSG data were independently scored by two to four certified PSG technologists, using standard Rechtschaffen and Kales guidelines, and these score files were combined on an epoch-by-epoch basis, using a majority voting rule, to generate a single score file per subject to compare against the Z-ALG output. Both epoch-by-epoch and standard sleep indices (eg, total sleep time, sleep efficiency, latency to persistent sleep, and wake after sleep onset) were compared between the Z-ALG output and the technologist consensus score files. Results Overall, the sensitivity and specificity for detecting sleep using the Z-ALG as compared to the technologist consensus are 95.5% and 92.5%, respectively, across all subjects, and the positive predictive value and the negative predictive value for detecting sleep are 98.0% and 84.2%, respectively. Overall κ agreement is 0.85 (approaching the level of agreement observed among sleep technologists). These results persist when the sleep disorder subgroups are analyzed separately. Conclusion This study demonstrates that the Z-ALG automated sleep

  3. Enhanced sediment loading facilitates point bar growth and accelerates bank erosion along a modelled meander bend on the Sacramento River, USA

    Science.gov (United States)

    Ahmed, Joshua; Constantine, José A.; Hales, Tristram C.

    2017-04-01

    Meandering channels provide a conduit through which sediment and water is routed from the uplands to the sea. Alluvial material is periodically stored and transported through the channel network as permitted by the prevailing hydrologic conditions. In the lowlands, this sediment often accumulates as point bar deposits attached to the inner banks of meander bends; previous research has highlighted the importance of these bedforms in facilitating the link between in-stream sediment supplies and channel dynamism. We use a 2D curvilinear hydrodynamic model (MIKE 21C) to perform a number of experiments in which we alter the sediment load to investigate how changes in alluvial material fluxes affect the development of point bars and the resultant patterns of bank erosion. We reveal that increasing the sediment load by up to two times the normal causes the point bar to grow both longitudinally and transversely; concurrently, near-bank shear stresses are elevated resulting in accelerated rates of bank retreat compared to normal sediment loads. Our results suggest that enhanced sediment loads (potentially the result of changes in land use or climate) can trigger enhanced rates of bank erosion and channel change through the sequestration of alluvial material on point bars, which then deflect high-velocity fluid towards the outer bank of the meander. These results have implications for the development of morphodynamic meander models which should consider the role of topographic flow accelerations induced by the presence of point bars more explicitly. Moreover, increased boundary shear stresses accelerate rates of bank retreat and therefore control rates of riparian habitat development as well as exchanges of sediment and nutrients between the channel and floodplain.

  4. Resolving Difficulties of a Single-Channel Partial-Wave Analysis

    Science.gov (United States)

    Hunt, Brian; Manley, D. Mark

    2016-03-01

    The goal of our research is to determine better the properties of nucleon resonances using techniques of a global multichannel partial-wave analysis. Currently, many predicted resonances have not been found, while the properties of several known resonances are relatively uncertain. To resolve these issues, one must analyze many different reactions in a multichannel fit. Other groups generally approach this problem by generating an energy-dependent fit from the start. This is a fit where all channels are analyzed together. The method is powerful, but due to the complex nature of resonances, certain model-dependent assumptions have to be introduced from the start. The current work tries to resolve these issues by first generating single-energy solutions in which experimental data are analyzed in narrow energy bins. The single-energy solutions can then be used to constrain the energy-dependent solution in a comparatively unbiased manner. Our work focuses on adding three new single-energy solutions into the global fit. These reactions are γp --> ηp , γn --> ηn , and γp -->K+ Λ . During this talk, I will discuss the difficulties of this approach, our methods to overcome these difficulties, and a few preliminary results. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Medium Energy Nuclear Physics, under Award Nos. DE-FG02-01ER41194 and DE-SC0014323 and by the Kent State University Department of Physics.

  5. Wireless multi-channel single unit recording in freely moving and vocalizing primates.

    Science.gov (United States)

    Roy, Sabyasachi; Wang, Xiaoqin

    2012-01-15

    The ability to record well-isolated action potentials from individual neurons in naturally behaving animals is crucial for understanding neural mechanisms underlying natural behaviors. Traditional neurophysiology techniques, however, require the animal to be restrained which often restricts natural behavior. An example is the common marmoset (Callithrix jacchus), a highly vocal New World primate species, used in our laboratory to study the neural correlates of vocal production and sensory feedback. When restrained by traditional neurophysiological techniques marmoset vocal behavior is severely inhibited. Tethered recording systems, while proven effective in rodents pose limitations in arboreal animals such as the marmoset that typically roam in a three-dimensional environment. To overcome these obstacles, we have developed a wireless neural recording technique that is capable of collecting single-unit data from chronically implanted multi-electrodes in freely moving marmosets. A lightweight, low power and low noise wireless transmitter (headstage) is attached to a multi-electrode array placed in the premotor cortex of the marmoset. The wireless headstage is capable of transmitting 15 channels of neural data with signal-to-noise ratio (SNR) comparable to a tethered system. To minimize radio-frequency (RF) and electro-magnetic interference (EMI), the experiments were conducted within a custom designed RF/EMI and acoustically shielded chamber. The individual electrodes of the multi-electrode array were periodically advanced to densely sample the cortical layers. We recorded single-unit data over a period of several months from the frontal cortex of two marmosets. These recordings demonstrate the feasibility of using our wireless recording method to study single neuron activity in freely roaming primates. Copyright © 2011 Elsevier B.V. All rights reserved.

  6. Anomalous passage of ultrarelativistic electrons in thick single crystals in axial channeling

    Energy Technology Data Exchange (ETDEWEB)

    Khokonov, M.K. (Moskovskij Gosudarstvennyj Univ. (USSR). Nauchno-Issledovatel' skij Inst. Yadernoj Fiziki); Telegin, V.I. (Gosudarstvennyj Komitet po Ispol' zovaniyu Atomnoj Ehnergii SSSR, Moscow. Inst. Atomnoj Ehnergii)

    1983-07-01

    The dynamics of ultrarelativistic axially channeled electrons in thick crystals is studied. It is revealed that a certain fraction of initial electrons have anomalously large dechanneling depths. It is shown also that the dechanneling depth in heavy and light crystals are comparable. In some cases, the number of channeled electrons can strongly increase at the expense of quasi-channeled electrons. The problem of quasi-channeling is also considered.

  7. Heteronuclear refocusing by nonlinear phase and amplitude modulation on a single transmitter channel.

    Science.gov (United States)

    Moore, Jay; Colón, Raul D; Tadanki, Sasidhar; Waddell, Kevin W

    2014-08-01

    The application of low magnetic fields to heteronuclear NMR has expanded recently alongside the emergence of methods for achieving near unity polarization of spin ensembles, independent of magnetic field strength. The parahydrogen induced hyperpolarization methods in particular, often use a hybrid arrangement where a high field spectrometer is used to detect or image polarized molecules that have been conjured on a separate, dedicated polarizer instrument operating at fields in the mT regime where yields are higher. For controlling polarizer chemistry, spare TTL channels of portable NMR spectrometers can be used to pulse program reaction timings in synchrony with heteronuclear RF transformations. The use of a spectrometer as a portable polarizer control module has the advantage of allowing detection in situ, simplifying the process of optimizing polarization yields prior to in vivo experimental trials. Suitable heteronuclear spectrometers compatible with this application are becoming more common, but are still sparsely available in comparison to a large existing infrastructure of single channel NMR consoles. With the goal of expanding the range of these systems to multinuclear applications, the feasibility of rotating a pair of heteronuclear spins ((13)C and (1)H) at 12mT was investigated in this study. Nonlinear phase and amplitude modulated waveforms designed to simultaneously refocus magnetization at 128kHz ((13)C) and 510kHz ((1)H) were generated numerically with optimal control. Although precise quantitative comparisons were not attempted due to limitations of the experimental setup, signals refocused at heteronuclear frequencies with this PANORAMIC approach (Precession And Nutation for Observing Rotation At Multiple Intervals about the Carrier) yielded amplitudes comparable to signals which were refocused using traditional block pulses on heteronuclear channels. Using this PANORAMIC approach to heteronuclear NMR at low field would reduce expense as well as

  8. Heteronuclear refocusing by nonlinear phase and amplitude modulation on a single transmitter channel

    Science.gov (United States)

    Moore, Jay; Colón, Raul D.; Tadanki, Sasidhar; Waddell, Kevin W.

    2014-08-01

    The application of low magnetic fields to heteronuclear NMR has expanded recently alongside the emergence of methods for achieving near unity polarization of spin ensembles, independent of magnetic field strength. The parahydrogen induced hyperpolarization methods in particular, often use a hybrid arrangement where a high field spectrometer is used to detect or image polarized molecules that have been conjured on a separate, dedicated polarizer instrument operating at fields in the mT regime where yields are higher. For controlling polarizer chemistry, spare TTL channels of portable NMR spectrometers can be used to pulse program reaction timings in synchrony with heteronuclear RF transformations. The use of a spectrometer as a portable polarizer control module has the advantage of allowing detection in situ, simplifying the process of optimizing polarization yields prior to in vivo experimental trials. Suitable heteronuclear spectrometers compatible with this application are becoming more common, but are still sparsely available in comparison to a large existing infrastructure of single channel NMR consoles. With the goal of expanding the range of these systems to multinuclear applications, the feasibility of rotating a pair of heteronuclear spins (13C and 1H) at 12 mT was investigated in this study. Nonlinear phase and amplitude modulated waveforms designed to simultaneously refocus magnetization at 128 kHz (13C) and 510 kHz (1H) were generated numerically with optimal control. Although precise quantitative comparisons were not attempted due to limitations of the experimental setup, signals refocused at heteronuclear frequencies with this PANORAMIC approach (Precession And Nutation for Observing Rotation At Multiple Intervals about the Carrier) yielded amplitudes comparable to signals which were refocused using traditional block pulses on heteronuclear channels. Using this PANORAMIC approach to heteronuclear NMR at low field would reduce expense as well as

  9. Entropy-enthalpy compensation at the single protein level: pH sensing in the bacterial channel OmpF

    Science.gov (United States)

    Alcaraz, Antonio; Queralt-Martín, María; Verdiá-Báguena, Carmina; Aguilella, Vicente M.; Mafé, Salvador

    2014-11-01

    The pH sensing mechanism of the OmpF channel operates via ligand modification: increasing acidity induces the replacement of cations with protons in critical binding sites decreasing the channel conductance. Aside from the change in enthalpy associated with the binding, there is also a change in the microscopic arrangements of ligands, receptors and the surrounding solvent. We show that the pH-modulation of the single channel conduction involves small free energy changes because large enthalpic and entropic contributions change in opposite ways, demonstrating an approximate enthalpy-entropy compensation for different salts and concentrations.The pH sensing mechanism of the OmpF channel operates via ligand modification: increasing acidity induces the replacement of cations with protons in critical binding sites decreasing the channel conductance. Aside from the change in enthalpy associated with the binding, there is also a change in the microscopic arrangements of ligands, receptors and the surrounding solvent. We show that the pH-modulation of the single channel conduction involves small free energy changes because large enthalpic and entropic contributions change in opposite ways, demonstrating an approximate enthalpy-entropy compensation for different salts and concentrations. Electronic supplementary information (ESI) available. See DOI: 10.1039/c4nr03811h

  10. A Mathematica package for calculation of planar channeling radiation spectra of relativistic electrons channeled in a diamond-structure single crystal (quantum approach)

    Science.gov (United States)

    Azadegan, B.

    2013-03-01

    The presented Mathematica code is an efficient tool for simulation of planar channeling radiation spectra of relativistic electrons channeled along major crystallographic planes of a diamond-structure single crystal. The program is based on the quantum theory of channeling radiation which has been successfully applied to study planar channeling at electron energies between 10 and 100 MeV. Continuum potentials for different planes of diamond, silicon and germanium single crystals are calculated using the Doyle-Turner approximation to the atomic scattering factor and taking thermal vibrations of the crystal atoms into account. Numerical methods are applied to solve the one-dimensional Schrödinger equation. The code is designed to calculate the electron wave functions, transverse electron states in the planar continuum potential, transition energies, line widths of channeling radiation and depth dependencies of the population of quantum states. Finally the spectral distribution of spontaneously emitted channeling radiation is obtained. The simulation of radiation spectra considerably facilitates the interpretation of experimental data. Catalog identifier: AEOH_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEOH_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 446 No. of bytes in distributed program, including test data, etc.: 209805 Distribution format: tar.gz Programming language: Mathematica. Computer: Platforms on which Mathematica is available. Operating system: Operating systems on which Mathematica is available. RAM: 1 MB Classification: 7.10. Nature of problem: Planar channeling radiation is emitted by relativistic charged particles during traversing a single crystal in direction parallel to a crystallographic plane. Channeling is modeled as the motion

  11. Single step sequential polydimethylsiloxane wet etching to fabricate a microfluidic channel with various cross-sectional geometries

    Science.gov (United States)

    Wang, C.-K.; Liao, W.-H.; Wu, H.-M.; Lo, Y.-H.; Lin, T.-R.; Tung, Y.-C.

    2017-11-01

    Polydimethylsiloxane (PDMS) has become a widely used material to construct microfluidic devices for various biomedical and chemical applications due to its desirable material properties and manufacturability. PDMS microfluidic devices are usually fabricated using soft lithography replica molding methods with master molds made of photolithogrpahy patterned photoresist layers on silicon wafers. The fabricated microfluidic channels often have rectangular cross-sectional geometries with single or multiple heights. In this paper, we develop a single step sequential PDMS wet etching process that can be used to fabricate microfluidic channels with various cross-sectional geometries from single-layer PDMS microfluidic channels. The cross-sections of the fabricated channel can be non-rectangular, and varied along the flow direction. Furthermore, the fabricated cross-sectional geometries can be numerically simulated beforehand. In the experiments, we fabricate microfluidic channels with various cross-sectional geometries using the developed technique. In addition, we fabricate a microfluidic mixer with alternative mirrored cross-sectional geometries along the flow direction to demonstrate the practical usage of the developed technique.

  12. Zn2(+)-induced subconductance events in cardiac Na+ channels prolonged by batrachotoxin. Current-voltage behavior and single-channel kinetics

    Science.gov (United States)

    1991-01-01

    The mechanism of voltage-dependent substate production by external Zn2+ in batrachotoxin-modified Na+ channels from canine heart was investigated by analysis of the current-voltage behavior and single- channel kinetics of substate events. At the single-channel level the addition of external Zn2+ results in an increasing frequency of substate events with a mean duration of approximately 15-25 ms for the substate dwell time observed in the range of -70 to +70 mV. Under conditions of symmetrical 0.2 M NaCl, the open state of cardiac Na+ channels displays ohmic current-voltage behavior in the range of -90 to +100 mV, with a slope conductance of 21 pS. In contrast, the Zn2(+)- induced substate exhibits significant outward rectification with a slope conductance of 3.1 pS in the range of -100 to -50 mV and 5.1 pS in the range of +50 to +100 mV. Analysis of dwell-time histograms of substate events as a function of Zn2+ concentration and voltage led to the consideration of two types of models that may explain this behavior. Using a simple one-site blocking model, the apparent association rate for Zn2+ binding is more strongly voltage dependent (decreasing e-fold per +60 mV) than the Zn2+ dissociation rate (increasing e-fold per +420 mV). However, this simple blocking model cannot account for the dependence of the apparent dissociation rate on Zn2+ concentration. To explain this result, a four-state kinetic scheme involving a Zn2(+)-induced conformational change from a high conductance conformation to a substate conformation is proposed. This model, similar to one introduced by Pietrobon et al. (1989. J. Gen. Physiol. 94:1-24) for H(+)-induced substate behavior in L-type Ca2+ channels, is able to simulate the kinetic and equilibrium behavior of the primary Zn2(+)-induced substate process in heart Na+ channels. This model implies that binding of Zn2+ greatly enhances conversion of the open, ohmic channel to a low conductance conformation with an asymmetric energy profile for

  13. Single SOA based 16 DWDM channels all-optical NRZ-to-RZ format conversions with different duty cycles.

    Science.gov (United States)

    Yu, Yu; Zhang, Xinliang; Rosas-Fernández, J B; Huang, Dexiu; Penty, R V; White, I H

    2008-09-29

    We demonstrate simultaneous NRZ-to-RZ conversion for 16 DWDM channels, using a single SOA and a subsequent delay interferometer (DI) acting as a comb-like filter to control the obtained pulse-width for all of the channels. The SOA is operated in deep saturation, resulting in weak cross gain modulation and cross phase modulation induced crosstalk between different NRZ channels. By adjusting the detuning between the peaks in the DI spectrum and each corresponding carrier, good quality RZ signals with different duty cycles can be achieved. Bit-error-rate measurements show negative power penalties for the obtained RZ signals with different duty cycles. Significant timing jitter reductions for all channels show the good regenerative performance of the proposed converter.

  14. A 184-year record of river meander migration from tree rings, aerial imagery, and cross sections

    Science.gov (United States)

    Schook, Derek M.; Rathburn, Sara L.; Friedman, Jonathan M.; Wolf, J. Marshall

    2017-09-01

    Channel migration is the primary mechanism of floodplain turnover in meandering rivers and is essential to the persistence of riparian ecosystems. Channel migration is driven by river flows, but short-term records cannot disentangle the effects of land use, flow diversion, past floods, and climate change. We used three data sets to quantify nearly two centuries of channel migration on the Powder River in Montana. The most precise data set came from channel cross sections measured an average of 21 times from 1975 to 2014. We then extended spatial and temporal scales of analysis using aerial photographs (1939-2013) and by aging plains cottonwoods along transects (1830-2014). Migration rates calculated from overlapping periods across data sets mostly revealed cross-method consistency. Data set integration revealed that migration rates have declined since peaking at 5 m/year in the two decades after the extreme 1923 flood (3000 m3/s). Averaged over the duration of each data set, cross section channel migration occurred at 0.81 m/year, compared to 1.52 m/year for the medium-length air photo record and 1.62 m/year for the lengthy cottonwood record. Powder River peak annual flows decreased by 48% (201 vs. 104 m3/s) after the largest flood of the post-1930 gaged record (930 m3/s in 1978). Declining peak discharges led to a 53% reduction in channel width and a 29% increase in sinuosity over the 1939-2013 air photo record. Changes in planform geometry and reductions in channel migration make calculations of floodplain turnover rates dependent on the period of analysis. We found that the intensively studied last four decades do not represent the past two centuries.

  15. River banks and channel axis curvature: Effects on the longitudinal dispersion in alluvial rivers

    Science.gov (United States)

    Lanzoni, Stefano; Ferdousi, Amena; Tambroni, Nicoletta

    2018-03-01

    The fate and transport of soluble contaminants released in natural streams are strongly dependent on the spatial variations of the flow field and of the bed topography. These variations are essentially related to the presence of the channel banks and to the planform configuration of the channel. Large velocity gradients arise near to the channel banks, where the flow depth decreases to zero. Moreover, single thread alluvial rivers are seldom straight, and usually exhibit meandering planforms and a bed topography that deviates from the plane configuration. Channel axis curvature and movable bed deformations drive secondary helical currents which enhance both cross sectional velocity gradients and transverse mixing, thus crucially influencing longitudinal dispersion. The present contribution sets up a rational framework which, assuming mild sloping banks and taking advantage of the weakly meandering character often exhibited by natural streams, leads to an analytical estimate of the contribution to longitudinal dispersion associated with spatial non-uniformities of the flow field. The resulting relationship stems from a physics-based modeling of the flow in natural rivers, and expresses the bend averaged longitudinal dispersion coefficient as a function of the relevant hydraulic and morphologic parameters. The treatment of the problem is river specific, since it relies on an explicit spatial description, although linearized, of the flow field that establishes in the investigated river. Comparison with field data available from tracer tests supports the robustness of the proposed framework, given also the complexity of the processes that affect dispersion dynamics in real streams.

  16. Discharge estimation in a backwater affected meandering river

    Directory of Open Access Journals (Sweden)

    H. Hidayat

    2011-08-01

    Full Text Available Variable effects of backwaters complicate the development of rating curves at hydrometric measurement stations. In areas influenced by backwater, single-parameter rating curve techniques are often inapplicable. To overcome this, several authors have advocated the use of an additional downstream level gauge to estimate the longitudinal surface level gradient, but this is cumbersome in a lowland meandering river with considerable transverse surface level gradients. Recent developments allow river flow to be continuously monitored through velocity measurements with an acoustic Doppler current profiler (H-ADCP, deployed horizontally at a river bank. This approach was adopted to obtain continuous discharge estimates at a cross-section in the River Mahakam at a station located about 300 km upstream of the river mouth in the Mahakam delta. The discharge station represents an area influenced by variable backwater effects from lakes, tributaries and floodplain ponds, and by tides. We applied both the standard index velocity method and a recently developed methodology to obtain a continuous time-series of discharge from the H-ADCP data. Measurements with a boat-mounted ADCP were used for calibration and validation of the model to translate H-ADCP velocity to discharge. As a comparison with conventional discharge estimation techniques, a stage-discharge relation using Jones formula was developed. The discharge rate at the station exceeded 3250 m3 s−1. Discharge series from a traditional stage-discharge relation did not capture the overall discharge dynamics, as inferred from H-ADCP data. For a specific river stage, the discharge range could be as high as 2000 m3 s−1, which is far beyond what could be explained from kinematic wave dynamics. Backwater effects from lakes were shown to be significant, whereas interaction of the river flow with tides may impact discharge variation in the fortnightly frequency band

  17. Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI

    Czech Academy of Sciences Publication Activity Database

    Taxt, T.; Jiřík, Radovan; Rygh, C. B.; Grüner, R.; Bartoš, M.; Andersen, E.; Curry, F. R.; Reed, R. K.

    2012-01-01

    Roč. 59, č. 4 (2012), s. 1012-1021 ISSN 0018-9294 Institutional support: RVO:68081731 Keywords : arterial input function (AIF) * blind deconvolution * dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) * multichannel * perfusion * single channel Subject RIV: BH - Optics, Masers, Lasers Impact factor: 2.348, year: 2012

  18. Single channel 112Gbit/sec PAM4 at 56Gbaud with digital signal processing for data centers applications.

    Science.gov (United States)

    Sadot, Dan; Dorman, G; Gorshtein, Albert; Sonkin, Eduard; Vidal, Or

    2015-01-26

    112Gbit/sec DSP-based single channel transmission of PAM4 at 56Gbaud over 15GHz of effective analog bandwidth is experimentally demonstrated. The DSP enables use of mature 25G optoelectronics for 2-10km datacenter intra-connections, and 8Tbit/sec over 80km interconnections between data centers.

  19. Channel characterization for single- and multiple-antenna wearable systems used for indoor body-to-body communications

    NARCIS (Netherlands)

    Cotton, Simon L.; Scanlon, W.G.

    In this paper, an analysis of radio channel characteristics for single- and multiple-antenna bodyworn systems for use in body-to-body communications is presented. The work was based on an extensive measurement campaign conducted at 2.45 GHz representative of an indoor sweep and search scenario for

  20. Single rat muscle Na+channel mutation confers batrachotoxin autoresistance found in poison-dart frogPhyllobates terribilis.

    Science.gov (United States)

    Wang, Sho-Ya; Wang, Ging Kuo

    2017-09-26

    Poison-dart Phyllobates terribilis frogs sequester lethal amounts of steroidal alkaloid batrachotoxin (BTX) in their skin as a defense mechanism against predators. BTX targets voltage-gated Na + channels and enables them to open persistently. How BTX autoresistance arises in such frogs remains a mystery. The BTX receptor has been delineated along the Na + channel inner cavity, which is formed jointly by four S6 transmembrane segments from domains D1 to D4. Within the P. terribilis muscle Na + channel, five amino acid (AA) substitutions have been identified at D1/S6 and D4/S6. We therefore investigated the role of these naturally occurring substitutions in BTX autoresistance by introducing them into rat Nav1.4 muscle Na + channel, both individually and in combination. Our results showed that combination mutants containing an N1584T substitution all conferred a complete BTX-resistant phenotype when expressed in mammalian HEK293t cells. The single N1584T mutant also retained its functional integrity and became exceptionally resistant to 5 µM BTX, aside from a small residual BTX effect. Single and combination mutants with the other four S6 residues (S429A, I433V, A445D, and V1583I) all remained highly BTX sensitive. These findings, along with diverse BTX phenotypes of N1584K/A/D/T mutant channels, led us to conclude that the conserved N1584 residue is indispensable for BTX actions, probably functioning as an integral part of the BTX receptor. Thus, complete BTX autoresistance found in P. terribilis muscle Na + channels could emerge primarily from a single AA substitution (asparagine→threonine) via a single nucleotide mutation (AAC→ACC).

  1. Observation of s-Channel Single Top Quark Production at the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Cremonesi, Matteo [Univ. of Oxford (United Kingdom)

    2014-01-01

    Testing the Standard Model (SM) and looking for new phenomena have been the focus of generations of particle physicists in the last decades. Following this spirit, this thesis presents two searches. The first is the search for single top quark production from the exchange of an s-channel virtual W boson using events with an imbalance in the total transverse energy, b-tagged jets, and no identified leptons. Assuming the electroweak production of top quarks of mass 172.5 GeV/c2 in the s-channel, a cross section of 1.12+0.61 -0.57 (stat+syst) pb, with a significance of 1.9 standard deviations, is measured. This measurement is combined with the result obtained from events with an imbalance in total transverse momentum, b-tagged jets, and exactly one identified lepton, yielding a cross section of 1.36+0.37 -0.322 (stat+syst) pb, with a significance of 4.2 standard deviations. The first observation of single-top-quark production in the s channel through the combination of the CDF and D0 measurements is also reported. The measured cross section is σs = 1.29+0.26 -0.244 pb. The probability of observing a statistical fluctuation of the background to a cross section of the observed size or larger is 1.8 10-10, corresponding to a significance of 6.3 standard deviation. The second is the search for W'-like resonances decaying to tb. No significant excess above the SM prediction is found. Using a benchmark W' → tb left-right symmetric model, 95% C.L. mass-dependent upper limits are placed on the W0 boson production cross section times branching ratio to tb. Assuming a W' boson with SM-like couplings and allowed (forbidden) decay to leptons, W' → tb is excluded with 95% C.L. for W' boson masses below 860 (880) GeV/c2. Relaxing the hypothesis on SM-like couplings, we exclude W' boson coupling strength values as a function of the W' boson mass

  2. Simulation Comparisons of Three Different Meander Line Dipoles

    Science.gov (United States)

    2015-01-01

    MH. Improving radiation characteristics of UHF RFID antennas by zigzag structures. IEEE Xplore Digital Library , 2014: n. pag. Web. 2 September 2014...Paez C I. Design formulas for a meandered dipole. IEEE Xplore Digital Library , 2014: n. pag. Web. 2 September 2014. 2. Nguyen, VH, Phan, HP, Hoang...geometry-based, frequency-independent lumped element model. IEEE Xplore Digital Library , 2014: n. pag. Web. 2 September 2014. 5. Olaode OO, Palmer WD

  3. Transient computation fluid dynamics modeling of a single proton exchange membrane fuel cell with serpentine channel

    Science.gov (United States)

    Hu, Guilin; Fan, Jianren

    The proton exchange membrane fuel cell (PEMFC) has become a promising candidate for the power source of electrical vehicles because of its low pollution, low noise and especially fast startup and transient responses at low temperatures. A transient, three-dimensional, non-isothermal and single-phase mathematical model based on computation fluid dynamics has been developed to describe the transient process and the dynamic characteristics of a PEMFC with a serpentine fluid channel. The effects of water phase change and heat transfer, as well as electrochemical kinetics and multicomponent transport on the cell performance are taken into account simultaneously in this comprehensive model. The developed model was employed to simulate a single laboratory-scale PEMFC with an electrode area about 20 cm 2. The dynamic behavior of the characteristic parameters such as reactant concentration, pressure loss, temperature on the membrane surface of cathode side and current density during start-up process were computed and are discussed in detail. Furthermore, transient responses of the fuel cell characteristics during step changes and sinusoidal changes in the stoichiometric flow ratio of the cathode inlet stream, cathode inlet stream humidity and cell voltage are also studied and analyzed and interesting undershoot/overshoot behavior of some variables was found. It was also found that the startup and transient response time of a PEM fuel cell is of the order of a second, which is similar to the simulation results predicted by most models. The result is an important guide for the optimization of PEMFC designs and dynamic operation.

  4. Miniature, Single Channel, Memory-Based, High-G Acceleration Recorder (Millipen)

    International Nuclear Information System (INIS)

    Rohwer, Tedd A.

    1999-01-01

    The Instrumentation and Telemetry Departments at Sandia National Laboratories have been instrumenting earth penetrators for over thirty years. Recorded acceleration data is used to quantify penetrator performance. Penetrator testing has become more difficult as desired impact velocities have increased. This results in the need for small-scale test vehicles and miniature instrumentation. A miniature recorder will allow penetrator diameters to significantly decrease, opening the window of testable parameters. Full-scale test vehicles will also benefit from miniature recorders by using a less intrusive system to instrument internal arming, fusing, and firing components. This single channel concept is the latest design in an ongoing effort to miniaturize the size and reduce the power requirement of acceleration instrumentation. A micro-controller/memory based system provides the data acquisition, signal conditioning, power regulation, and data storage. This architecture allows the recorder, including both sensor and electronics, to occupy a volume of less than 1.5 cubic inches, draw less than 200mW of power, and record 15kHz data up to 40,000 gs. This paper will describe the development and operation of this miniature acceleration recorder

  5. A single-channel 10-bit 160 MS/s SAR ADC in 65 nm CMOS

    Science.gov (United States)

    Yuxiao, Lu; Lu, Sun; Zhe, Li; Jianjun, Zhou

    2014-04-01

    This paper demonstrates a single-channel 10-bit 160 MS/s successive-approximation-register (SAR) analog-to-digital converter (ADC) in 65 nm CMOS process with a 1.2 V supply voltage. To achieve high speed, a new window-opening logic based on the asynchronous SAR algorithm is proposed to minimize the logic delay, and a partial set-and-down DAC with binary redundancy bits is presented to reduce the dynamic comparator offset and accelerate the DAC settling. Besides, a new bootstrapped switch with a pre-charge phase is adopted in the track and hold circuits to increase speed and reduce area. The presented ADC achieves 52.9 dB signal-to-noise distortion ratio and 65 dB spurious-free dynamic range measured with a 30 MHz input signal at 160 MHz clock. The power consumption is 9.5 mW and a core die area of 250 × 200 μm2 is occupied.

  6. Additive Manufacturing Thermal Performance Testing of Single Channel GRCop-84 SLM Components

    Science.gov (United States)

    Garcia, Chance P.; Cross, Matthew

    2014-01-01

    The surface finish found on components manufactured by sinter laser manufacturing (SLM) is rougher (0.013 - 0.0006 inches) than parts made using traditional fabrication methods. Internal features and passages built into SLM components do not readily allow for roughness reduction processes. Alternatively, engineering literature suggests that the roughness of a surface can enhance thermal performance within a pressure drop regime. To further investigate the thermal performance of SLM fabricated pieces, several GRCop-84 SLM single channel components were tested using a thermal conduction rig at MSFC. A 20 kW power source running at 25% duty cycle and 25% power level applied heat to each component while varying water flow rates between 2.1 - 6.2 gallons/min (GPM) at a supply pressure of 550 to 700 psi. Each test was allowed to reach quasi-steady state conditions where pressure, temperature, and thermal imaging data were recorded. Presented in this work are the heat transfer responses compared to a traditional machined OHFC Copper test section. An analytical thermal model was constructed to anchor theoretical models with the empirical data.

  7. Cross-section measurement of single-top t-channel production at ATLAS

    CERN Document Server

    Herrberg-Schubert, Ruth

    2014-06-02

    This study presents the cross-section measurement of electroweak single-top quark production in the t-channel with a semi-leptonically decaying top quark. The study is based on 4.7 fb^{-1} of proton-proton collision data recorded with the ATLAS detector at the Large Hadron Collider in the year 2011. Selected events contain two highly energetic jets, one of which is identified as originating from a beauty quark, as well as a highly energetic electron or muon and transverse missing energy. The case of three and four jets is also considered but eventually discarded since their inclusion degrades the precision of the result. The event reconstruction is done with a chi-square-based kinematic fit using W boson and top quark mass constraints. The chi-square value in each event serves to classify the event as a signal-like or background-like process. The cross-section is extracted by performing a template-based maximum likelihood fit to the distribution that displays the best discriminatory power: This distribution i...

  8. Portable single channel analyzer incorporated with a GM counter for radiation protection

    International Nuclear Information System (INIS)

    Chenghsin Mao

    1988-01-01

    A compact size of single channel analyzer incorporated with a GM counter has been developed. It measures 8.7 cm (W) x 22.2 cm (L) x 4.4 cm (H) and weighs 0.58 kg excluding the detectors. An adjustable high voltage of 0-1000 V is included with an error of ± 0.1% and powered by three mercury batteries of 9 V each. Both the upper and lower level discriminators are set at 0 - 5 V with an error of ± 1%. The timer can be set at either 0 - 99 sec or 0 - 99 min with a buzzer alarm. The resolution of pulse is 5 μs plus the pulse width. The LCD display is either 3 1/2 or 4 digits. The rise time of shaping circuit is 1 μs with a band width of 350 kHz. The voltage indicator for battery is set at 7.5 V. All integrated circuits are of CMOS with low cost OPAMP. Some examples for field applications are given

  9. Single channel planar lipid bilayer recordings of the melittin variant MelP5.

    Science.gov (United States)

    Fennouri, Aziz; Mayer, Simon Finn; Schroeder, Thomas B H; Mayer, Michael

    2017-10-01

    MelP5 is a 26 amino acid peptide derived from melittin, the main active constituent of bee venom, with five amino acid replacements. The pore-forming activity of MelP5 in lipid membranes is attracting attention because MelP5 forms larger pores and induces dye leakage through liposome membranes at a lower concentration than melittin. Studies of MelP5 have so far focused on ensemble measurements of membrane leakage and impedance; here we extend this characterization with an electrophysiological comparison between MelP5 and melittin using planar lipid bilayer recordings. These experiments reveal that MelP5 pores in lipid membranes composed of 3:1 phosphatidylcholine:cholesterol consist of an average of 10 to 12 monomers compared to an average of 3 to 9 monomers for melittin. Both peptides form transient pores with dynamically varying conductance values similar to previous findings for melittin, but MelP5 occasionally also forms stable, well-defined pores with single channel conductance values that vary greatly and range from 50 to 3000pS in an electrolyte solution containing 100mM KCl. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  10. Effect of intermittent hypoxic training on hypoxia tolerance based on single-channel EEG.

    Science.gov (United States)

    Zhang, Tinglin; Wang, You; Li, Guang

    2016-03-23

    A single-channel algorithm was proposed in order to study effect of intermittent hypoxic training on hypoxia tolerance based on EEG pattern. EEG was decomposed by ensemble empirical mode decomposition into a finite number of intrinsic mode functions (IMFs) based on the intrinsic local characteristic time scale. Analytic amplitude, analytic frequency, and recurrence property quantified by recurrence quantification analysis were explored on IMFs, and the first two scales revealed difference between normal EEG and hypoxia EEG. Classification accuracy of hypoxia EEG and normal EEG could reach 67.8% before decline of neurobehavioral ability, which represented that hypoxia EEG pattern could be detected at an early stage. Classification accuracy of hypoxia EEG and normal EEG increased with time and deepened intensity of hypoxia was observed by regular shift of hypoxia EEG pattern with time in a three dimensional subspace. The reduced shift and classification accuracy after intermittent hypoxic training represented that hypoxia tolerance enhanced. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. Multiband Bandstop Filter using an I-Stub-Loaded Meandered Defected Microstrip Structure

    Directory of Open Access Journals (Sweden)

    G. R. Koirala

    2016-04-01

    Full Text Available This paper presents a compact multiband bandstop filter (BSF that utilizes an I-stub embedded within a meandered defected microstrip structure (MDMS. The proposed design for obtaining a single stopband is analyzed by using a transmission line network model. On the basis of the single stopband structure, we designed and fabricated a dual- and tri-band bandstop filters operating at 2.5/6.78 GHz and 1.98/5.60/7.78 GHz, respectively, thereby exploring the concept of generating as many stopbands by simply adding the same number of I-stubs. The proposed filter also features the possibility of tuning the resonant frequencies by varying the width of the I-stubs.

  12. Anomalous passage of ultrarelativistic electrons in thick single crystals in axial channeling

    International Nuclear Information System (INIS)

    Khokonov, M.K.; Telegin, V.I.

    1983-01-01

    The dynamics of ultrarelativistic axially channeled electrons in thick crystals is studied. It is revealed that a certain fraction of initial electrons have anomalously large dechanneling depths. It is shown also that the dechanneling depth in heavy and light crystals are comparable. In some cases, the number of channeled electrons can strongly increase at the expense of quasi-channeled electrons. The problem of quasichanneling is also considered. (author)

  13. Single channel atmospheric pressure transporting plasma and plasma stream demultiplexing: physical characterization and application to E. coli bacteria inactivation

    International Nuclear Information System (INIS)

    Valinataj Omran, A; Arefi-Khonsari, F; Sohbatzadeh, F; Siadati, S N; Hosseinzadeh Colagar, A; Akishev, Y

    2017-01-01

    In this article, we developed transporting plasma sources that operate at atmospheric pressure. The effect of electrode configuration on plasma transporting was investigated. In order to increase the transporting plasma cross-section, we converted a plasma stream into four plasma channels by a cylindrical housing. Electron excitation and rotational temperatures were estimated using optical emission spectroscopy. Furthermore, the electrical and temporal characteristics of the plasma, discharge power and charge deposition on the target were investigated. The propagation characteristics of single and multi-channel transporting plasma were compared with the same cross-sectional area. Two configurations for multi-channels were designed for this purpose. Escherichia coli bacteria were exposed to the single and multi-channel transporting discharge for different time durations. After exposure, the results indicated that the inactivation zones were significantly increased by a multi-channel transporting plasma. Finally, E. coli inactivation by those plasma apparatuses was compared with that of several standard antimicrobial test discs such as Gentamicin, Tetracycline, Amoxicillin and Cefixime. (paper)

  14. Fluorescence-based high-throughput functional profiling of ligand-gated ion channels at the level of single cells.

    Directory of Open Access Journals (Sweden)

    Sahil Talwar

    Full Text Available Ion channels are involved in many physiological processes and are attractive targets for therapeutic intervention. Their functional properties vary according to their subunit composition, which in turn varies in a developmental and tissue-specific manner and as a consequence of pathophysiological events. Understanding this diversity requires functional analysis of ion channel properties in large numbers of individual cells. Functional characterisation of ligand-gated channels involves quantitating agonist and drug dose-response relationships using electrophysiological or fluorescence-based techniques. Electrophysiology is limited by low throughput and high-throughput fluorescence-based functional evaluation generally does not enable the characterization of the functional properties of each individual cell. Here we describe a fluorescence-based assay that characterizes functional channel properties at single cell resolution in high throughput mode. It is based on progressive receptor activation and iterative fluorescence imaging and delivers >100 dose-responses in a single well of a 384-well plate, using α1-3 homomeric and αβ heteromeric glycine receptor (GlyR chloride channels as a model system. We applied this assay with transiently transfected HEK293 cells co-expressing halide-sensitive yellow fluorescent protein and different GlyR subunit combinations. Glycine EC50 values of different GlyR isoforms were highly correlated with published electrophysiological data and confirm previously reported pharmacological profiles for the GlyR inhibitors, picrotoxin, strychnine and lindane. We show that inter and intra well variability is low and that clustering of functional phenotypes permits identification of drugs with subunit-specific pharmacological profiles. As this method dramatically improves the efficiency with which ion channel populations can be characterized in the context of cellular heterogeneity, it should facilitate systems

  15. Design and characterization of a single channel two-liquid capacitor and its application to hyperelastic strain sensing.

    Science.gov (United States)

    Liu, Shanliangzi; Sun, Xiaoda; Hildreth, Owen J; Rykaczewski, Konrad

    2015-03-07

    Room temperature liquid-metal microfluidic devices are attractive systems for hyperelastic strain sensing. These liquid-phase electronics are intrinsically soft and retain their functionality even when stretched to several times their original length. Currently two types of liquid metal-based strain sensors exist for in-plane measurements: single-microchannel resistive and two-microchannel capacitive devices. With a winding serpentine channel geometry, these sensors typically have a footprint of about a square centimeter. This large footprint of an individual device limits the number of sensors that can be embedded into, for example, electronic fabric or skin. In this work we introduce an alternative capacitor design consisting of two liquid metal electrodes separated by a liquid dielectric material within a single straight channel. Using a liquid insulator instead of a solid elastomer enables us to tailor the system's capacitance by selecting high or low dielectric constant liquids. We quantify the effects of the electrode geometry including the diameter, spacing, and meniscus shape as well as the dielectric constant of the insulating liquid on the overall system's capacitance. We also develop a procedure for fabricating the two-liquid capacitor within a single straight polydiemethylsiloxane channel and demonstrate that this device can have about 25 times higher capacitance per sensor's base area when compared to two-channel liquid metal capacitors. Lastly, we characterize the response of this compact device to strain and identify operational issues arising from complex hydrodynamics near liquid-liquid and liquid-elastomer interfaces.

  16. Changes in I K, ACh single-channel activity with atrial tachycardia remodelling in canine atrial cardiomyocytes.

    Science.gov (United States)

    Voigt, Niels; Maguy, Ange; Yeh, Yung-Hsin; Qi, Xiaoyan; Ravens, Ursula; Dobrev, Dobromir; Nattel, Stanley

    2008-01-01

    Although atrial tachycardia (AT) remodelling promotes agonist-independent, constitutively active, acetylcholine-regulated K+-current (I K,ACh) that increases susceptibility to atrial fibrillation (AF), the underlying changes in I K,Ach channel function are unknown. This study aimed to establish how AT remodelling affects I K,ACh single-channel function. I K,ACh single-channel activity was studied via cell-attached patch-clamp in isolated left atrial cardiomyocytes of control and AT (7 days, 400 min(-1)) dogs. Atrial tachycardia prolonged the mean duration of induced AF from 44 +/- 22 to 413 +/- 167 s, and reduced atrial effective refractory period at a 360 ms cycle length from 126 +/- 3 to 74 +/- 5 ms (n = 9/group, P ACh conductance and rectification properties were sparse under control conditions. Atrial tachycardia induced prominent agonist-independent I K,ACh activity because of increased opening frequency (fo) and open probability (Po: approximately seven- and 10-fold, respectively, vs. control), but did not alter open time-constant, single-channel conductance, and membrane density. With maximum I K,ACh activation (10 micromol/L carbachol), channel Po was enhanced much more in control cells ( approximately 42-fold) than in AT-remodelled myocytes (approximately five-fold). The selective Kir3 current blocker tertiapin-Q (100 nmol/L) reduced fo and Po at -100 mV by 48 and 51%, respectively (P ACh. Atrial tachycardia had no significant effect on mRNA or protein expression of either of the subunits (Kir3.1, Kir3.4) underlying I K,ACh. Atrial tachycardia increases agonist-independent constitutive I K,ACh single-channel activity by enhancing spontaneous channel opening, providing a molecular basis for AT effects on macroscopic I K,ACh observed in previous studies, as well as associated refractoriness abbreviation and tertiapin-suppressible AF promotion. These results suggest an important role for constitutive I K,Ach channel opening in AT remodelling and support its

  17. Negative compressibility of selenium chains confined in the channels of AlPO4-5 single crystals

    International Nuclear Information System (INIS)

    Ren Wei; Ye Jianting; Shi Wu; Tang Zikang; Chan, C T; Sheng Ping

    2009-01-01

    Pressure-induced structural and electronic variations of Se helical chains confined in nano-channels of zeolite single crystals are studied. Raman and optical absorption spectra provide us with evidence of softened vibration modes and band gap reduction under high pressure. We reveal that the Se chains elongate under hydrostatic compression by ab initio calculations. The changes in morphology lead to a softening of phonons and narrowing of energy gaps consistent with observations from optical measurements. The present investigation demonstrates negative compressibility of Se chains in one-dimensional channels of a zeolite framework.

  18. Channel capacity of TDD-OFDM-MIMO for multiple access points in a wireless single-frequency-network

    DEFF Research Database (Denmark)

    Takatori, Y.; Fitzek, Frank; Tsunekawa, K.

    2005-01-01

    MIMO data transmission scheme, which combines Single-Frequency-Network (SFN) with TDD-OFDM-MIMO applied for wireless LAN networks. In our proposal, we advocate to use SFN for multiple access points (MAP) MIMO data transmission. The goal of this approach is to achieve very high channel capacity in both...... LOS and non line of sight (NLOS) environments. The channel capacity of the proposed method is derived for the direct path environments and it confirms the effectiveness of the proposed scheme in the LOS scenario. Moreover, solid computer simulation results confirm the effectiveness of the proposed...

  19. Channeling and Radiation of Electrons in Silicon Single Crystals and Si1−xGex Crystalline Undulators

    DEFF Research Database (Denmark)

    Backe, H.; Krambrich, D.; Lauth, W.

    2013-01-01

    The phenomenon of channeling and the basic features of channeling radiation emission are introduced in a pedestrian way. Both, radiation spectra as well as dechanneling length measurements at electron beam energies between 195 and 855 MeV feature quantum state phenomena for the (110) planar...... potential of the silicon single crystals. Radiation from a crystalline undulator, produced at the Aarhus University (UAAR), has been investigated at the Mainz Microtron electron accelerator facility MAMI. The 4-period epitaxially grown strained layer Si1−xGex undulator had a period length λu = 9.9 μm...

  20. Role of the potential landscape on the single-file diffusion through channels.

    Science.gov (United States)

    Goldt, S D; Terentjev, E M

    2014-12-14

    Transport of colloid particles through narrow channels is ubiquitous in cell biology as well as becoming increasingly important for microfluidic applications or targeted drug delivery. Membrane channels in cells are useful models for artificial designs because of their high efficiency, selectivity, and robustness to external fluctuations. Here, we model the passive channels that let cargo simply diffuse through them, affected by a potential profile along the way. Passive transporters achieve high levels of efficiency and specificity from binding interactions with the cargo inside the channel. This however leads to a paradox: why should channels which are so narrow that they are blocked by their cargo evolve to have binding regions for their cargo if that will effectively block them? Using Brownian dynamics simulations, we show that different potentials, notably symmetric, increase the flux through narrow passive channels - and investigate how shape and depth of potentials influence the flux. We find that there exist optimal depths for certain potential shapes and that it is most efficient to apply a small force over an extended region of the channel. On the other hand, having several spatially discrete binding pockets will not alter the flux significantly. We also explore the role of many-particle effects arising from pairwise particle interactions with their neighbours and demonstrate that the relative changes in flux can be accounted for by the kinetics of the absorption reaction at the end of the channel.

  1. Channelling and channelling radiation

    International Nuclear Information System (INIS)

    Soerensen, A.H.; Uggerhoej, E.

    1987-01-01

    The study of channelling phenomena has developed rapidly since the early 1960s and today channelling has found many applications. The radiation emitted by channelled megaelectronvolt and gigaelectronvolt electrons and positrons has been investigated extensively and the possibility of, for example, constructing intense tunable X- and γ-ray sources is being explored. Multi-gigaelectronvolt radiation and pair-creation processes in single crystals show similarities with strong-field effects and are of particular interest because of high production rates that persist far beyond the channelling regime. (author)

  2. Polypeptide Translocation Through the Mitochondrial TOM Channel: Temperature-Dependent Rates at the Single-Molecule Level.

    Science.gov (United States)

    Mahendran, Kozhinjampara R; Lamichhane, Usha; Romero-Ruiz, Mercedes; Nussberger, Stephan; Winterhalter, Mathias

    2013-01-03

    The TOM protein complex facilitates the transfer of nearly all mitochondrial preproteins across outer mitochondrial membranes. Here we characterized the effect of temperature on facilitated translocation of a mitochondrial presequence peptide pF1β. Ion current fluctuations analysis through single TOM channels revealed thermodynamic and kinetic parameters of substrate binding and allowed determining the energy profile of peptide translocation. The activation energy for the on-rate and off-rate of the presequence peptide into the TOM complex was symmetric with respect to the electric field and estimated to be about 15 and 22 kT per peptide. These values are above that expected for free diffusion of ions in water (6 kT) and reflect the stronger interaction in the channel. Both values are in the range for typical enzyme kinetics and suggest one process without involving large conformational changes within the channel protein.

  3. Development of TUF-ELOCA - a software tool for integrated single-channel thermal-hydraulic and fuel element analyses

    International Nuclear Information System (INIS)

    Popescu, A.I.; Wu, E.; Yousef, W.W.; Pascoe, J.; Parlatan, Y.; Kwee, M.

    2006-01-01

    The TUF-ELOCA tool couples the TUF and ELOCA codes to enable an integrated thermal-hydraulic and fuel element analysis for a single channel during transient conditions. The coupled architecture is based on TUF as the parent process controlling multiple ELOCA executions that simulate the fuel elements behaviour and is scalable to different fuel channel designs. The coupling ensures a proper feedback between the coolant conditions and fuel elements response, eliminates model duplications, and constitutes an improvement from the prediction accuracy point of view. The communication interfaces are based on PVM and allow parallelization of the fuel element simulations. Developmental testing results are presented showing realistic predictions for the fuel channel behaviour during a transient. (author)

  4. Potent neutralization of influenza A virus by a single-domain antibody blocking M2 ion channel protein.

    Directory of Open Access Journals (Sweden)

    Guowei Wei

    Full Text Available Influenza A virus poses serious health threat to humans. Neutralizing antibodies against the highly conserved M2 ion channel is thought to offer broad protection against influenza A viruses. Here, we screened synthetic Camel single-domain antibody (VHH libraries against native M2 ion channel protein. One of the isolated VHHs, M2-7A, specifically bound to M2-expressed cell membrane as well as influenza A virion, inhibited replication of both amantadine-sensitive and resistant influenza A viruses in vitro, and protected mice from a lethal influenza virus challenge. Moreover, M2-7A showed blocking activity for proton influx through M2 ion channel. These pieces of evidence collectively demonstrate for the first time that a neutralizing antibody against M2 with broad specificity is achievable, and M2-7A may have potential for cross protection against a number of variants and subtypes of influenza A viruses.

  5. Interfacing sensory input with motor output: does the control architecture converge to a serial process along a single channel?

    Science.gov (United States)

    van de Kamp, Cornelis; Gawthrop, Peter J; Gollee, Henrik; Lakie, Martin; Loram, Ian D

    2013-01-01

    Modular organization in control architecture may underlie the versatility of human motor control; but the nature of the interface relating sensory input through task-selection in the space of performance variables to control actions in the space of the elemental variables is currently unknown. Our central question is whether the control architecture converges to a serial process along a single channel? In discrete reaction time experiments, psychologists have firmly associated a serial single channel hypothesis with refractoriness and response selection [psychological refractory period (PRP)]. Recently, we developed a methodology and evidence identifying refractoriness in sustained control of an external single degree-of-freedom system. We hypothesize that multi-segmental whole-body control also shows refractoriness. Eight participants controlled their whole body to ensure a head marker tracked a target as fast and accurately as possible. Analysis showed enhanced delays in response to stimuli with close temporal proximity to the preceding stimulus. Consistent with our preceding work, this evidence is incompatible with control as a linear time invariant process. This evidence is consistent with a single-channel serial ballistic process within the intermittent control paradigm with an intermittent interval of around 0.5 s. A control architecture reproducing intentional human movement control must reproduce refractoriness. Intermittent control is designed to provide computational time for an online optimization process and is appropriate for flexible adaptive control. For human motor control we suggest that parallel sensory input converges to a serial, single channel process involving planning, selection, and temporal inhibition of alternative responses prior to low dimensional motor output. Such design could aid robots to reproduce the flexibility of human control.

  6. Electro-oxidized epitaxial graphene channel field-effect transistors with single-walled carbon nanotube thin film gate electrode.

    Science.gov (United States)

    Ramesh, Palanisamy; Itkis, Mikhail E; Bekyarova, Elena; Wang, Feihu; Niyogi, Sandip; Chi, Xiaoliu; Berger, Claire; de Heer, Walt; Haddon, Robert C

    2010-10-20

    We report the effect of electrochemical oxidation in nitric acid on the electronic properties of epitaxial graphene (EG) grown on silicon carbide substrates; we demonstrate the availability of an additional reaction channel in EG, which is not present in graphite but which facilitates the introduction of the reaction medium into the graphene galleries during electro-oxidation. The device performance of the chemically processed graphene was studied by patterning the EG wafers with two geometrically identical macroscopic channels; the electro-oxidized channel showed a logarithmic increase of resistance with decreasing temperature, which is ascribed to the scattering of charge carriers in a two-dimensional electronic gas, rather than the presence of an energy gap at the Fermi level. Field-effect transistors were fabricated on the electro-oxidized and pristine graphene channels using single-walled carbon nanotube thin film top gate electrodes, thereby allowing the study of the effect of oxidative chemistry on the transistor performance of EG. The electro-oxidized channel showed higher values for the on-off ratio and the mobility of the graphene field-effect transistor, which we ascribe to the availability of high-quality internal graphene layers after electro-oxidation of the more defective top layers. Thus, the present oxidative process provides a clear contrast with previously demonstrated covalent chemistry in which sp(3) hybridized carbon atoms are introduced into the graphitic transport layer of the lattice by carbon-carbon bond formation, thereby opening an energy gap.

  7. Historic channel change on Esopus Creek, upstream of the Ashokan Reservoir, Catskills, New York

    Science.gov (United States)

    Miller, Nicolas Ross

    An understanding of historic channel change is fundamental to informing good stream management decisions. This study correlated the history of recent channel change on Esopus Creek in the Catskill Mountains of New York to patterns in the hydrologic record in order to understand the role of hydrologic controls on the stream's changing morphology. This study identified dynamic stream segments that have the potential to impact infrastructure and water quality in this watershed, which supplies a significant portion of New York City's drinking water. Changes in channel width, sinuosity, channel index and meander migration were obtained from quantitative analysis of aerial imagery from 1959, 1980 and 2001, along with historic topographic maps and field reconnaissance. Discharge patterns correlated with observed morphologic changes, while the role of other controlling variables such as basin and valley geography, climate, changing land use and historic channelization was explored. While there were no significant net changes in active channel width for the overall study period, overall channel width decreased between 1959 and 1980 and increased between 1980 and 2001. Reach-scale changes in channel width followed the same trend, with most reaches narrowing between 1959 and 1980 and widening between 1980 and 2001. The frequency and timing of large flow events were more significant in producing morphologic changes than the magnitude of a single event. The flood of record in 1980, which followed a 22-year hiatus in large flows, appears to have performed limited channel-width changes, while smaller magnitude but more frequent flows had much greater effects. Furthermore, time periods during which moderate flows, approximating bankfull conditions, occurred more frequently were correlated to periods of channel widening, whereas periods of less frequent moderate flows were correlated to periods of channel narrowing. Overall channel sinuosity did not change significantly over the

  8. Free energy dissipation of the spontaneous gating of a single voltage-gated potassium channel

    Science.gov (United States)

    Wang, Jia-Zeng; Wang, Rui-Zhen

    2018-02-01

    Potassium channels mainly contribute to the resting potential and re-polarizations, with the potassium electrochemical gradient being maintained by the pump Na+/K+-ATPase. In this paper, we construct a stochastic model mimicking the kinetics of a potassium channel, which integrates temporal evolving of the membrane voltage and the spontaneous gating of the channel. Its stationary probability density functions (PDFs) are found to be singular at the boundaries, which result from the fact that the evolving rates of voltage are greater than the gating rates of the channel. We apply PDFs to calculate the power dissipations of the potassium current, the leakage, and the gating currents. On a physical perspective, the essential role of the system is the K+-battery charging the leakage (L-)battery. A part of power will inevitably be dissipated among the process. So, the efficiency of energy transference is calculated.

  9. Bit Error Rate Minimizing Channel Shortening Equalizers for Single Carrier Cyclic Prefixed Systems

    National Research Council Canada - National Science Library

    Martin, Richard K; Vanbleu, Koen; Ysebaert, Geert

    2007-01-01

    .... Previous work on channel shortening has largely been in the context of digital subscriber lines, a wireline system that allows bit allocation, thus it has focused on maximizing the bit rate for a given bit error rate (BER...

  10. Changes in Single K+ Channel Behavior Induced by a Lipid Phase Transition

    Science.gov (United States)

    Seeger, Heiko M.; Aldrovandi, Laura; Alessandrini, Andrea; Facci, Paolo

    2010-01-01

    We show that the activity of an ion channel is correlated with the phase state of the lipid bilayer hosting the channel. By measuring unitary conductance, dwell times, and open probability of the K+ channel KcsA as a function of temperature in lipid bilayers composed of POPE and POPG in different relative proportions, we obtain that all those properties show a trend inversion when the bilayer is in the transition region between the liquid-disordered and the solid-ordered phase. These data suggest that the physical properties of the lipid bilayer influence ion channel activity likely via a fine-tuning of its conformations. In a more general interpretative framework, we suggest that other parameters such as pH, ionic strength, and the action of amphiphilic drugs can affect the physical behavior of the lipid bilayer in a fashion similar to temperature changes resulting in functional changes of transmembrane proteins. PMID:21112292

  11. Multifloquet to Single Electronic Channel Transition in the Transport Properties of a Resistive 1D Driven Disordered Ring

    Science.gov (United States)

    Foieri, Federico; Arrachea, Liliana; Sánchez, María José

    2007-12-01

    We investigate the dc response of a 1D disordered ring coupled to a reservoir and driven by a magnetic flux with a linear dependence on time. We identify two regimes: (i) A localized or large length L regime, characterized by a dc conductance, gdc, whose probability distribution P(gdc) is identical to the one exhibited by a 1D wire of the same length L and disorder strength placed in a two terminal Landauer setup and (ii) a multifloquet regime for small L and weak coupling to the reservoir, which exhibits large currents and conductances that can be gdc>1, in spite of the fact that the ring contains spinless electrons and a single electronic transmission channel. The crossover length between the multifloquet to the single-channel transport regime Lc is controlled by the coupling to the reservoir.

  12. Alluvial cover controlling the width, slope and sinuosity of bedrock channels

    Science.gov (United States)

    Turowski, Jens Martin

    2018-02-01

    Bedrock channel slope and width are important parameters for setting bedload transport capacity and for stream-profile inversion to obtain tectonics information. Channel width and slope development are closely related to the problem of bedrock channel sinuosity. It is therefore likely that observations on bedrock channel meandering yields insights into the development of channel width and slope. Active meandering occurs when the bedrock channel walls are eroded, which also drives channel widening. Further, for a given drop in elevation, the more sinuous a channel is, the lower is its channel bed slope in comparison to a straight channel. It can thus be expected that studies of bedrock channel meandering give insights into width and slope adjustment and vice versa. The mechanisms by which bedrock channels actively meander have been debated since the beginning of modern geomorphic research in the 19th century, but a final consensus has not been reached. It has long been argued that whether a bedrock channel meanders actively or not is determined by the availability of sediment relative to transport capacity, a notion that has also been demonstrated in laboratory experiments. Here, this idea is taken up by postulating that the rate of change of both width and sinuosity over time is dependent on bed cover only. Based on the physics of erosion by bedload impacts, a scaling argument is developed to link bedrock channel width, slope and sinuosity to sediment supply, discharge and erodibility. This simple model built on sediment-flux-driven bedrock erosion concepts yields the observed scaling relationships of channel width and slope with discharge and erosion rate. Further, it explains why sinuosity evolves to a steady-state value and predicts the observed relations between sinuosity, erodibility and storm frequency, as has been observed for meandering bedrock rivers on Pacific Arc islands.

  13. Monte Carlo uncertainty analysis of dose estimates in radiochromic film dosimetry with single-channel and multichannel algorithms.

    Science.gov (United States)

    Vera-Sánchez, Juan Antonio; Ruiz-Morales, Carmen; González-López, Antonio

    2018-03-01

    To provide a multi-stage model to calculate uncertainty in radiochromic film dosimetry with Monte-Carlo techniques. This new approach is applied to single-channel and multichannel algorithms. Two lots of Gafchromic EBT3 are exposed in two different Varian linacs. They are read with an EPSON V800 flatbed scanner. The Monte-Carlo techniques in uncertainty analysis provide a numerical representation of the probability density functions of the output magnitudes. From this numerical representation, traditional parameters of uncertainty analysis as the standard deviations and bias are calculated. Moreover, these numerical representations are used to investigate the shape of the probability density functions of the output magnitudes. Also, another calibration film is read in four EPSON scanners (two V800 and two 10000XL) and the uncertainty analysis is carried out with the four images. The dose estimates of single-channel and multichannel algorithms show a Gaussian behavior and low bias. The multichannel algorithms lead to less uncertainty in the final dose estimates when the EPSON V800 is employed as reading device. In the case of the EPSON 10000XL, the single-channel algorithms provide less uncertainty in the dose estimates for doses higher than four Gy. A multi-stage model has been presented. With the aid of this model and the use of the Monte-Carlo techniques, the uncertainty of dose estimates for single-channel and multichannel algorithms are estimated. The application of the model together with Monte-Carlo techniques leads to a complete characterization of the uncertainties in radiochromic film dosimetry. Copyright © 2018 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  14. Removal of Muscle Artifacts from Single-Channel EEG Based on Ensemble Empirical Mode Decomposition and Multiset Canonical Correlation Analysis

    Directory of Open Access Journals (Sweden)

    Xun Chen

    2014-01-01

    Full Text Available Electroencephalogram (EEG recordings are often contaminated with muscle artifacts. This disturbing muscular activity strongly affects the visual analysis of EEG and impairs the results of EEG signal processing such as brain connectivity analysis. If multichannel EEG recordings are available, then there exist a considerable range of methods which can remove or to some extent suppress the distorting effect of such artifacts. Yet to our knowledge, there is no existing means to remove muscle artifacts from single-channel EEG recordings. Moreover, considering the recently increasing need for biomedical signal processing in ambulatory situations, it is crucially important to develop single-channel techniques. In this work, we propose a simple, yet effective method to achieve the muscle artifact removal from single-channel EEG, by combining ensemble empirical mode decomposition (EEMD with multiset canonical correlation analysis (MCCA. We demonstrate the performance of the proposed method through numerical simulations and application to real EEG recordings contaminated with muscle artifacts. The proposed method can successfully remove muscle artifacts without altering the recorded underlying EEG activity. It is a promising tool for real-world biomedical signal processing applications.

  15. Modeling satellite-Earth quantum channel downlinks with adaptive-optics coupling to single-mode fibers

    Science.gov (United States)

    Gruneisen, Mark T.; Flanagan, Michael B.; Sickmiller, Brett A.

    2017-12-01

    The efficient coupling of photons from a free-space quantum channel into a single-mode optical fiber (SMF) has important implications for quantum network concepts involving SMF interfaces to quantum detectors, atomic systems, integrated photonics, and direct coupling to a fiber network. Propagation through atmospheric turbulence, however, leads to wavefront errors that degrade mode matching with SMFs. In a free-space quantum channel, this leads to photon losses in proportion to the severity of the aberration. This is particularly problematic for satellite-Earth quantum channels, where atmospheric turbulence can lead to significant wavefront errors. This report considers propagation from low-Earth orbit to a terrestrial ground station and evaluates the efficiency with which photons couple either through a circular field stop or into an SMF situated in the focal plane of the optical receiver. The effects of atmospheric turbulence on the quantum channel are calculated numerically and quantified through the quantum bit error rate and secure key generation rates in a decoy-state BB84 protocol. Numerical simulations include the statistical nature of Kolmogorov turbulence, sky radiance, and an adaptive-optics system under closed-loop control.

  16. Characteristics of single large-conductance Ca2+-activated K+ channels and their regulation of action potentials and excitability in parasympathetic cardiac motoneurons in the nucleus ambiguus.

    Science.gov (United States)

    Lin, Min; Hatcher, Jeff T; Wurster, Robert D; Chen, Qin-Hui; Cheng, Zixi Jack

    2014-01-15

    Large-conductance Ca2(+)-activated K+ channels (BK) regulate action potential (AP) properties and excitability in many central neurons. However, the properties and functional roles of BK channels in parasympathetic cardiac motoneurons (PCMNs) in the nucleus ambiguus (NA) have not yet been well characterized. In this study, the tracer X-rhodamine-5 (and 6)-isothiocyanate (XRITC) was injected into the pericardial sac to retrogradely label PCMNs in FVB mice at postnatal 7-9 days. Two days later, XRITC-labeled PCMNs in brain stem slices were identified. Using excised patch single-channel recordings, we identified voltage-gated and Ca(2+)-dependent BK channels in PCMNs. The majority of BK channels exhibited persistent channel opening during voltage holding. These BK channels had a conductance of 237 pS and a 50% opening probability at +27.9 mV, the channel open time constant was 3.37 ms at +20 mV, and dwell time increased exponentially as the membrane potential depolarized. At the +20-mV holding potential, the [Ca2+]50 was 15.2 μM with a P0.5 of 0.4. Occasionally, some BK channels showed a transient channel opening and fast inactivation. Using whole cell voltage clamp, we found that BK channel mediated outward currents and afterhyperpolarization currents (IAHP). Using whole cell current clamp, we found that application of BK channel blocker iberiotoxin (IBTX) increased spike half-width and suppressed fast afterhyperpolarization (fAHP) amplitude following single APs. In addition, IBTX application increased spike half-width and reduced the spike frequency-dependent AP broadening in trains and spike frequency adaption (SFA). Furthermore, BK channel blockade decreased spike frequency. Collectively, these results demonstrate that PCMNs have BK channels that significantly regulate AP repolarization, fAHP, SFA, and spike frequency. We conclude that activation of BK channels underlies one of the mechanisms for facilitation of PCMN excitability.

  17. Design of a Single Channel Modulated Wideband Converter for Wideband Spectrum Sensing: Theory, Architecture and Hardware Implementation.

    Science.gov (United States)

    Liu, Weisong; Huang, Zhitao; Wang, Xiang; Sun, Weichao

    2017-05-04

    In a cognitive radio sensor network (CRSN), wideband spectrum sensing devices which aims to effectively exploit temporarily vacant spectrum intervals as soon as possible are of great importance. However, the challenge of increasingly high signal frequency and wide bandwidth requires an extremely high sampling rate which may exceed today's best analog-to-digital converters (ADCs) front-end bandwidth. Recently, the newly proposed architecture called modulated wideband converter (MWC), is an attractive analog compressed sensing technique that can highly reduce the sampling rate. However, the MWC has high hardware complexity owing to its parallel channel structure especially when the number of signals increases. In this paper, we propose a single channel modulated wideband converter (SCMWC) scheme for spectrum sensing of band-limited wide-sense stationary (WSS) signals. With one antenna or sensor, this scheme can save not only sampling rate but also hardware complexity. We then present a new, SCMWC based, single node CR prototype System, on which the spectrum sensing algorithm was tested. Experiments on our hardware prototype show that the proposed architecture leads to successful spectrum sensing. And the total sampling rate as well as hardware size is only one channel's consumption of MWC.

  18. Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers. Changes in unit conductance and in block by saxitoxin and calcium

    Science.gov (United States)

    Worley JF; French, RJ; Krueger, BK

    1986-01-01

    Single batrachotoxin-activated sodium channels from rat brain were modified by trimethyloxonium (TMO) after incorporation in planar lipid bilayers. TMO modification eliminated saxitoxin (STX) sensitivity, reduced the single channel conductance by 37%, and reduced calcium block of inward sodium currents. These effects always occurred concomitantly, in an all-or-none fashion. Calcium and STX protected sodium channels from TMO modification with potencies similar to their affinities for block. Calcium inhibited STX binding to rat brain membrane vesicles and relieved toxin block of channels in bilayers, apparently by competing with STX for the toxin binding site. These results suggest that toxins, permeant cations, and blocking cations can interact with a common site on the sodium channel near the extracellular surface. It is likely that permeant cations transiently bind to this superficial site, as the first of several steps in passing inward through the channel. PMID:2419487

  19. A permeation theory for single-file ion channels: one- and two-step models.

    Science.gov (United States)

    Nelson, Peter Hugo

    2011-04-28

    How many steps are required to model permeation through ion channels? This question is investigated by comparing one- and two-step models of permeation with experiment and MD simulation for the first time. In recent MD simulations, the observed permeation mechanism was identified as resembling a Hodgkin and Keynes knock-on mechanism with one voltage-dependent rate-determining step [Jensen et al., PNAS 107, 5833 (2010)]. These previously published simulation data are fitted to a one-step knock-on model that successfully explains the highly non-Ohmic current-voltage curve observed in the simulation. However, these predictions (and the simulations upon which they are based) are not representative of real channel behavior, which is typically Ohmic at low voltages. A two-step association/dissociation (A/D) model is then compared with experiment for the first time. This two-parameter model is shown to be remarkably consistent with previously published permeation experiments through the MaxiK potassium channel over a wide range of concentrations and positive voltages. The A/D model also provides a first-order explanation of permeation through the Shaker potassium channel, but it does not explain the asymmetry observed experimentally. To address this, a new asymmetric variant of the A/D model is developed using the present theoretical framework. It includes a third parameter that represents the value of the "permeation coordinate" (fractional electric potential energy) corresponding to the triply occupied state n of the channel. This asymmetric A/D model is fitted to published permeation data through the Shaker potassium channel at physiological concentrations, and it successfully predicts qualitative changes in the negative current-voltage data (including a transition to super-Ohmic behavior) based solely on a fit to positive-voltage data (that appear linear). The A/D model appears to be qualitatively consistent with a large group of published MD simulations, but no

  20. Post hoc pattern matching: assigning significance to statistically defined expression patterns in single channel microarray data

    Directory of Open Access Journals (Sweden)

    Blalock Eric M

    2007-07-01

    Full Text Available Abstract Background Researchers using RNA expression microarrays in experimental designs with more than two treatment groups often identify statistically significant genes with ANOVA approaches. However, the ANOVA test does not discriminate which of the multiple treatment groups differ from one another. Thus, post hoc tests, such as linear contrasts, template correlations, and pairwise comparisons are used. Linear contrasts and template correlations work extremely well, especially when the researcher has a priori information pointing to a particular pattern/template among the different treatment groups. Further, all pairwise comparisons can be used to identify particular, treatment group-dependent patterns of gene expression. However, these approaches are biased by the researcher's assumptions, and some treatment-based patterns may fail to be detected using these approaches. Finally, different patterns may have different probabilities of occurring by chance, importantly influencing researchers' conclusions about a pattern and its constituent genes. Results We developed a four step, post hoc pattern matching (PPM algorithm to automate single channel gene expression pattern identification/significance. First, 1-Way Analysis of Variance (ANOVA, coupled with post hoc 'all pairwise' comparisons are calculated for all genes. Second, for each ANOVA-significant gene, all pairwise contrast results are encoded to create unique pattern ID numbers. The # genes found in each pattern in the data is identified as that pattern's 'actual' frequency. Third, using Monte Carlo simulations, those patterns' frequencies are estimated in random data ('random' gene pattern frequency. Fourth, a Z-score for overrepresentation of the pattern is calculated ('actual' against 'random' gene pattern frequencies. We wrote a Visual Basic program (StatiGen that automates PPM procedure, constructs an Excel workbook with standardized graphs of overrepresented patterns, and lists of

  1. Swimming of Paramecium in confined channels

    Science.gov (United States)

    Jung, Sunghwan

    2012-02-01

    Many living organisms in nature have developed a few different swimming modes, presumably derived from hydrodynamic advantage. Paramecium is a ciliated protozoan covered by thousands of cilia with a few nanometers in diameter and tens of micro-meters in length and is able to exhibit both ballistic and meandering motions. First, we characterize ballistic swimming behaviors of ciliated microorganisms in glass capillaries of different diameters and explain the trajectories they trace out. We develop a theoretical model of an undulating sheet with a pressure gradient and discuss how it affects the swimming speed. Secondly, investigation into meandering swimmings within rectangular PDMS channels of dimension smaller than Paramecium length. We find that Paramecium executes a body-bend (an elastic buckling) using the cilia while it meanders. By considering an elastic beam model, we estimate and show the universal profile of forces it exerts on the walls. Finally, we discuss a few other locomotion of Paramecium in other extreme environments like gel.

  2. Historical perspectives on channel pattern in the Clark Fork River, Montana and implications for post-dam removal restoration

    Science.gov (United States)

    Woelfle-Erskine, C. A.; Wilcox, A. C.

    2009-12-01

    Active restoration approaches such as channel reconstruction have moved beyond the realm of small streams and are being applied to larger rivers. Uncertainties arising from limited knowledge, fluvial and ecosystem variability, and contaminants are especially significant in restoration of large rivers, where project costs and the social, infrastructural, and ecological costs of failure are high. We use the case of Milltown Dam removal on the Clark Fork River, Montana and subsequent channel reconstruction in the former reservoir to examine the use of historical research and uncertainty analysis in river restoration. At a cost of approximately $120 million, the Milltown Dam removal involves the mechanical removal of approximately 2 million cubic meters of sediments contaminated by upstream mining, followed by restoration of the former reservoir reach in which a single-thread meandering channel is being constructed. Historical maps, surveys, photographs, and accounts suggest a conceptual model of a multi-thread, anastomosing river in the reach targeted for channel reconstruction, upstream of the confluence of the Clark Fork and Blackfoot Rivers. We supplemented historical research with analysis of aerial photographs, topographic data, and USGS stage-discharge measurements in a lotic but reservoir-influenced reach of the Clark Fork River within our study area to estimate avulsion frequency (0.8 avulsions/year over a 70-year period) and average rates of lateral migration and aggradation. These were used to calculate the mobility number, a dimensionless relationship between channel filling and lateral migration timescales that can be used to predict whether a river’s planform is single or multi-threaded. The mobility number within our study reach ranged from 0.6 (multi-thread channel) to 1.7 (transitional channel). We predict that, in the absence of active channel reconstruction, the post-dam channel pattern would evolve to one that alternates between single and multi

  3. Creep in Al single crystal processed by equal-channel angular pressing

    Czech Academy of Sciences Publication Activity Database

    Král, Petr; Dvořák, Jiří; Šedá, Petra; Jäger, Aleš; Sklenička, Václav

    -, č. 3 (2011), od 50-do 50 [Bulk nanostructured materials: from fundamentals to innovations BNM2011. 23.08.2011-26.08.2011, Ufa] R&D Projects: GA AV ČR KAN300100801; GA ČR GPP108/10/P469 Institutional research plan: CEZ:AV0Z20410507; CEZ:AV0Z10100520 Keywords : ultrafine-grained materials * creep behaviour * equal-channel angular pressing Subject RIV: JJ - Other Materials

  4. Optimal power allocation of a single transmitter-multiple receivers channel in a cognitive sensor network

    KAUST Repository

    Ayala Solares, Jose Roberto

    2012-08-01

    The optimal transmit power of a wireless sensor network with one transmitter and multiple receivers in a cognitive radio environment while satisfying independent peak, independent average, sum of peak and sum of average transmission rate constraints is derived. A suboptimal scheme is proposed to overcome the frequency of outages for the independent peak transmission rate constraint. In all cases, numerical results are provided for Rayleigh fading channels. © 2012 IEEE.

  5. Gothic simulation of single-channel fuel heatup following a loss of forced flow

    Energy Technology Data Exchange (ETDEWEB)

    Chen, X-Q; Tahir, A. [NSS, Dept. of Thermal Hydraulics Analysis, Toronto, Ontario (Canada); Parlatan, Y. [Ontario Power Generation, NSATD, Pickering, Ontario (Canada); Kwee, M. [Bruce Power, NSASD, Toronto, Ontario (Canada)

    2011-07-01

    GOTHIC v7.2 was used to develop a computer model for the simulation of 28- and 37-element fuel heat-up at a loss of forced flow. The model has accounted for the non-uniformity of both axial and radial power distributions along the fuel channel for a typical CANDU reactor. In addition, the model has also accounted for the fuel rods, end-fittings, feeders and headers. Experimental test conditions for both 28- and 37-element bundles at either low or high powers were used for model validation. GOTHIC predictions of the rod and/or pressure-tube temperatures at a variety of test locations were compared with the corresponding experimental measurements. It is found that the numerical results agree well with the experimental measurements for most of the test locations. Results have also shown that the channel venting time is sensitive to the initial temperature distribution in the feeders and headers. An imposed temperature asymmetry at the beginning will cause the channel flow to vent earlier. (author)

  6. Single-phase convection heat transfer characteristics of pebble-bed channels with internal heat generation

    International Nuclear Information System (INIS)

    Meng Xianke; Sun Zhongning; Xu Guangzhan

    2012-01-01

    Graphical abstract: The core of the water-cooled pebble bed reactor is the porous channels which stacked with spherical fuel elements. The gaps between the adjacent fuel elements are complex because they are stochastic and often shift. We adopt electromagnetic induction heating method to overall heat the pebble bed. By comparing and analyzing the experimental data, we get the rule of power distribution and the rule of heat transfer coefficient with particle diameter, heat flux density, inlet temperature and working fluid's Re number. Highlights: ► We adopt electromagnetic induction heating method to overall heat the pebble bed to be the internal heat source. ► The ball diameter is smaller, the effect of the heat transfer is better. ► With Re number increasing, heat transfer coefficient is also increasing and eventually tends to stabilize. ► The changing of heat power makes little effect on the heat transfer coefficient of pebble bed channels. - Abstract: The reactor core of a water-cooled pebble bed reactor includes porous channels that are formed by spherical fuel elements. This structure has notably improved heat transfer. Due to the variability and randomness of the interstices in pebble bed channels, heat transfer is complex, and there are few studies regarding this topic. To study the heat transfer characters of pebble bed channels with internal heat sources, oxidized stainless steel spheres with diameters of 3 and 8 mm and carbon steel spheres with 8 mm diameters are used in a stacked pebble bed. Distilled water is used as a refrigerant for the experiments, and the electromagnetic induction heating method is used to heat the pebble bed. By comparing and analyzing the experimental results, we obtain the governing rules for the power distribution and the heat transfer coefficient with respect to particle diameter, heat flux density, inlet temperature and working fluid Re number. From fitting of the experimental data, we obtain the dimensionless average

  7. Channel morphology change of an allogenic river channel in a very arid environment due to human interventions

    Science.gov (United States)

    Yu, Guo-An; Disse, Markus; Qing Huang, He; Liu, Xiaofang

    2017-04-01

    Hydrological and fluvial processes of many dryland rivers have already been strongly influenced by various human interventions such as land reclamation and flow regulation, as the result of the accelerated expansion of human activities from temperate and humid environments into arid environments. Gauged hydrological data, channel bed survey and satellite images were used to analyze the temporal change of channel morphology of the main stem Tarim River, an allogenic river channel flowing in a very arid environment in northwest China, responding to ever increasing human impacts in recent decades. Surveyed channel cross sectional profiles in the upper reaches have shown that the mean channel bed elevation was in a fluctuating and silting trend in the last three decades, and the aggradation majorly occurred after the flood season, whereas scouring (incision) mainly occurred during the main flood season. The mean channel width and braiding intensity of the upper braided reaches followed an obvious decreasing trend. The channel embankments and gradual reclamation (occupation) of previous river flood plains and convex banks to farmlands is the major cause for the channel narrowing. The mean channel width and sinuosity index of the middle meandering reach in recent decades showed a gentle decreasing and increasing trend, respectively. The sinuosity index also differed quite clearly between the current and old (abandoned) channels. The meandering intensities (mean sinuosity index over a certain channel reach) of current meandering channels were obviously lower than the old channels. Human activity has changed the fluvial processes of the Tarim River and has restrained, to some extent, the evolution of channel patterns (meander development and channel avulsion).

  8. Visual CRO display of pulse height distribution including discriminator setting for a single channel X-ray analyser

    International Nuclear Information System (INIS)

    Shaw, S.E.

    1979-01-01

    An outline for a simple pulse spectroscope which attaches to a standard laboratory CRO is presented. The peak amplitude voltage of each pulse from the linear amplifier of a single channel X-ray analyser is stored for the duration of one oscilloscope trace. For each amplifier pulse, input from the discriminator is tested and if these is coincidence of pulses the oscilloscope beam is blanked for approximately the first 2 cm of its traverse across the screen. Repetition of pulses forms a pulse height distribution with a rectangular dark area marking the position of the discriminator window. (author)

  9. Thin film complementary metal oxide semiconductor (CMOS) device using a single-step deposition of the channel layer

    KAUST Repository

    Nayak, Pradipta K.

    2014-04-14

    We report, for the first time, the use of a single step deposition of semiconductor channel layer to simultaneously achieve both n-and p-type transport in transparent oxide thin film transistors (TFTs). This effect is achieved by controlling the concentration of hydroxyl groups (OH-groups) in the underlying gate dielectrics. The semiconducting tin oxide layer was deposited at room temperature, and the maximum device fabrication temperature was 350C. Both n and p-type TFTs showed fairly comparable performance. A functional CMOS inverter was fabricated using this novel scheme, indicating the potential use of our approach for various practical applications.

  10. SINGLE CHANNEL SEISMIC APPLICATION FOR GAS CHARGED SEDIMENT RECONNAISSANCE IN GEOHAZARD STUDY OF PORT CONSTRUCTION AT WETLAND AREA

    Directory of Open Access Journals (Sweden)

    Taufan Wiguna

    2016-10-01

    Full Text Available Gas charged sediment as a one of parameter for geohazard study in infrastructure especially in swamp area. Instability of sediment layer for exampel subsidence and landslide result in geohazard potention that caused by gas charged sediment. Seismic single channel can be used to identufy gas charged sediment location. Seabed morphology is collected from bathymetry and tidal survey. From seismic profile interpretation shows gas charged sediment indication in Line A and Line B. That indication emerged by presence of acoustic turbid zone and acoustic blanking. Line A and Line B location will be spotlight in next geotechnic port construction study.

  11. Two-dimensional numerical simulation of the effect of single event burnout for n-channel VDMOSFET

    International Nuclear Information System (INIS)

    Guo Hongxia; Chen Yusheng; Wang Wei; Zhao Jinlong; Zhang Yimen; Zhou Hui

    2004-01-01

    2D MEDICI simulator is used to investigate the effect of Single Event Burnout (SEB) for n-channel power VDMOSFETs. The simulation results are consistent with experimental results which have been published. The simulation results are of great interest for a better understanding of the occurrence of events. The effects of the minority carrier lifetime in the base region, the base width and the emitter doping density on SEB susceptibility are verified. Some hardening solutions to SEB are provided. The work shows that the 2D simulator MEDICI is an useful tool for burnout prediction and for the evaluation of hardening solutions. (authors)

  12. search for single top quark production in the s-channel by the CMS at 8 TeV

    CERN Document Server

    Rezaei Hosseinabadi, Ferdos

    2015-01-01

    Results of the search for single top-quark production in the s-channel in p-p collisions at a center-of-mass energy of 8TeV by the CMS experiment at the LHC will be presented. Leptonic decays mode of top quarks with an electron or muon in the final state are considered . In order to separate the expected signal from background processes, a multivariate discriminant is defined using Boosted Decision Trees. This analysis leads to an upper limit on the cross section of 11.5 Pb, corresponding to 2.1 times the standard model cross section, at 95pct Confidence Level.

  13. Application of the single-channel continuous synthesis method to criticity and power distribution calculations in thermal reactors

    International Nuclear Information System (INIS)

    Medrano Asensio, Gregorio.

    1976-06-01

    A detailed power distribution calculation in a large power reactor requires the solution of the multigroup 3D diffusion equations. Using the finite difference method, this computation is too expensive to be performed for design purposes. This work is devoted to the single channel continous synthesis method: the choice of the trial functions and the determination of the mixing functions are discussed in details; 2D and 3D results are presented. The method is applied to the calculation of the IAEA ''Benchmark'' reactor and the results obtained are compared with a finite element resolution and with published results [fr

  14. Flow tests of a single fuel element coolant channel for a compact fast reactor for space power

    Science.gov (United States)

    Springborn, R. H.

    1971-01-01

    Water flow tests were conducted on a single-fuel-element cooling channel for a nuclear concept to be used for space power. The tests established a method for measuring coolant flow rate which is applicable to water flow testing of a complete mockup of the reference reactor. The inlet plenum-to-outlet plenum pressure drop, which approximates the overall core pressure drop, was measured and correlated with flow rate. This information can be used for reactor coolant flow and heat transfer calculations. An analytical study of the flow characteristics was also conducted.

  15. The influence of tributary flow density differences on the hydrodynamic behavior of a confluent meander bend and implications for flow mixing

    Science.gov (United States)

    Herrero, Horacio S.; Díaz Lozada, José M.; García, Carlos M.; Szupiany, Ricardo N.; Best, Jim; Pagot, Mariana

    2018-03-01

    The goal of this study is to evaluate the influence of tributary flow density differences on hydrodynamics and mixing at a confluent meander bend. A detailed field characterization is performed using an Acoustic Doppler Current Profiler (ADCP) for quantification of the 3D flow field, flow discharge and bathymetry, as well as CTD measurements (conductivity, temperature, depth) to characterize the patterns of mixing. Satellite images of the confluence taken at complementary times to the field surveys were analyzed to evaluate the confluence hydrodynamics at different flow conditions. The results illustrate the differences in hydrodynamics and mixing length in relation to confluences with equal density tributaries. At low-density differences, and higher discharge ratio (Qr) between the two rivers, the flow is similar to equi-density confluent meander bends. In contrast, at high-density differences (low Qr), the tributary flow is confined to near the confluence but the density difference causes the flow to move across channel. In this case, the density difference causes the lateral spread of the tributary flow to be greater than at a greater Qr when the density difference is less. These results illustrate the potential importance of density differences between tributaries in determining the rate and spatial extent of mixing and sediment dispersal at confluent meander bends.

  16. 1.28 Tbit/s/channel single-polarization DQPSK transmission over 525 km using ultrafast time-domain optical Fourier transformation

    DEFF Research Database (Denmark)

    Guan, P.; Mulvad, Hans Christian Hansen; Tomiyama, Y.

    2010-01-01

    A single-channel 1.28 Tbit/s transmission over 525 km is demonstrated for the first time with a single-polarization DQPSK signal. Ultrafast time-domain optical Fourier transformation is successfully applied to DQPSK signals and results in improved performance and increased system margin.......A single-channel 1.28 Tbit/s transmission over 525 km is demonstrated for the first time with a single-polarization DQPSK signal. Ultrafast time-domain optical Fourier transformation is successfully applied to DQPSK signals and results in improved performance and increased system margin....

  17. Automated high-dose rate brachytherapy treatment planning for a single-channel vaginal cylinder applicator

    Science.gov (United States)

    Zhou, Yuhong; Klages, Peter; Tan, Jun; Chi, Yujie; Stojadinovic, Strahinja; Yang, Ming; Hrycushko, Brian; Medin, Paul; Pompos, Arnold; Jiang, Steve; Albuquerque, Kevin; Jia, Xun

    2017-06-01

    High dose rate (HDR) brachytherapy treatment planning is conventionally performed manually and/or with aids of preplanned templates. In general, the standard of care would be elevated by conducting an automated process to improve treatment planning efficiency, eliminate human error, and reduce plan quality variations. Thus, our group is developing AutoBrachy, an automated HDR brachytherapy planning suite of modules used to augment a clinical treatment planning system. This paper describes our proof-of-concept module for vaginal cylinder HDR planning that has been fully developed. After a patient CT scan is acquired, the cylinder applicator is automatically segmented using image-processing techniques. The target CTV is generated based on physician-specified treatment depth and length. Locations of the dose calculation point, apex point and vaginal surface point, as well as the central applicator channel coordinates, and the corresponding dwell positions are determined according to their geometric relationship with the applicator and written to a structure file. Dwell times are computed through iterative quadratic optimization techniques. The planning information is then transferred to the treatment planning system through a DICOM-RT interface. The entire process was tested for nine patients. The AutoBrachy cylindrical applicator module was able to generate treatment plans for these cases with clinical grade quality. Computation times varied between 1 and 3 min on an Intel Xeon CPU E3-1226 v3 processor. All geometric components in the automated treatment plans were generated accurately. The applicator channel tip positions agreed with the manually identified positions with submillimeter deviations and the channel orientations between the plans agreed within less than 1 degree. The automatically generated plans obtained clinically acceptable quality.

  18. Single production of the top partner in the T → tZ channel at the LHeC

    Science.gov (United States)

    Zhang, Yan-Ju; Han, Lin; Liu, Yao-Bei

    2017-05-01

    In this paper, we study the possibility of detecting the heavy vector-like top partner T in a simplified model with the decay channel T → tZ at the Large Hadron Electron Collider (LHeC). We first investigate the single top partner production process including the intergenerational mixing and the results show that the mixing between the top partner with the first generation can largely enhance the production cross section. We further study the observability of the single top partner through the process e+ p → T (→ tZ)νbare → t (→ bjj‧) Z (→ℓ+ℓ-)νbare at the LHeC with the proposed 140 GeV electron beam and 7 TeV proton beam. For some typical heavy T quark masses, the 3σ exclusion limits as well as the 5σ discovery region are respectively presented in terms of parameter space regions.

  19. Single production of the top partner in the T→tZ channel at the LHeC

    Directory of Open Access Journals (Sweden)

    Yan-Ju Zhang

    2017-05-01

    Full Text Available In this paper, we study the possibility of detecting the heavy vector-like top partner T in a simplified model with the decay channel T→tZ at the Large Hadron Electron Collider (LHeC. We first investigate the single top partner production process including the intergenerational mixing and the results show that the mixing between the top partner with the first generation can largely enhance the production cross section. We further study the observability of the single top partner through the process e+p→T(→tZν¯e→t(→bjj′Z(→ℓ+ℓ−ν¯e at the LHeC with the proposed 140 GeV electron beam and 7 TeV proton beam. For some typical heavy T quark masses, the 3σ exclusion limits as well as the 5σ discovery region are respectively presented in terms of parameter space regions.

  20. Weibull aging models for the single protective channel unavailability analysis by the device of stages

    International Nuclear Information System (INIS)

    Nunes, M.E.C.; Noriega, H.C.; Melo, P.F.F.

    1997-01-01

    Among the features to take into account in the unavailability analysis of protective channels, there is one that plays a dominant role - that of considering the equipment aging. In this sense, the exponential failure model is not adequate, since some transition rates are no more constant. As a consequence, Markovian models cannot be used anymore. As an alternative, one may use the device of stages that allows for transforming a Non Markovian model into an equivalent Markovian one by insertion of a fictitious states set, called stages. For a given time-dependent transition rate, its failure density is analysed as to the best combination of exponential distributions and then the moments of the original distribution and those of the combination are matched to estimate the necessary parameters. In this paper, the aging of the protective channel is supposed to follow Weibull distributions. Typical means and variances for the times to failure are considered and combinations of stages are checked. Initial conditions features are discussed in connection with states that are fictitious and to check the validity of the developed models. Alternative solutions by the discretization of the failure rates are generated. The results obtained agree quite well. (author). 7 refs., 6 figs

  1. Effects of atmospheric turbulence on the single-photon receiving efficiency and the performance of quantum channel with the modified approximate elliptic-beam model assumption

    Science.gov (United States)

    Wang, Xiao-yang; Zhao, Nan; Chen, Nan; Zhu, Chang-hua; Pei, Chang-xing

    2018-01-01

    In free space quantum channel, with the introduction and implementation of the satellite-ground link transmission, the researches of single-photon transmission have attracted great interest. We propose a single-photon receiving model and analyze the influence of the atmospheric turbulence on the single-photon transmission. We obtain the relationship between single-photon receiving efficiency and atmospheric turbulence, and analyze the influence of the atmospheric turbulence on the quantum channel performance by the single-photon counting. Finally, we present a reasonable simulation analysis. Simulation results show that as the strength of the atmospheric fluctuations increases, the counting distribution gradually broadens, and the utilization of quantum channel drops. Furthermore, the key generation rate and transmission distance decreases sharply in the case of strong turbulence.

  2. An Improved Single-Channel Method to Retrieve Land Surface Temperature from the Landsat-8 Thermal Band

    Directory of Open Access Journals (Sweden)

    Jordi Cristóbal

    2018-03-01

    Full Text Available Land surface temperature (LST is one of the sources of input data for modeling land surface processes. The Landsat satellite series is the only operational mission with more than 30 years of archived thermal infrared imagery from which we can retrieve LST. Unfortunately, stray light artifacts were observed in Landsat-8 TIRS data, mostly affecting Band 11, currently making the split-window technique impractical for retrieving surface temperature without requiring atmospheric data. In this study, a single-channel methodology to retrieve surface temperature from Landsat TM and ETM+ was improved to retrieve LST from Landsat-8 TIRS Band 10 using near-surface air temperature (Ta and integrated atmospheric column water vapor (w as input data. This improved methodology was parameterized and successfully evaluated with simulated data from a global and robust radiosonde database and validated with in situ data from four flux tower sites under different types of vegetation and snow cover in 44 Landsat-8 scenes. Evaluation results using simulated data showed that the inclusion of Ta together with w within a single-channel scheme improves LST retrieval, yielding lower errors and less bias than models based only on w. The new proposed LST retrieval model, developed with both w and Ta, yielded overall errors on the order of 1 K and a bias of −0.5 K validated against in situ data, providing a better performance than other models parameterized using w and Ta or only w models that yielded higher error and bias.

  3. Real-time single image dehazing based on dark channel prior theory and guided filtering

    Science.gov (United States)

    Zhang, Zan

    2017-10-01

    Images and videos taken outside the foggy day are serious degraded. In order to restore degraded image taken in foggy day and overcome traditional Dark Channel prior algorithms problems of remnant fog in edge, we propose a new dehazing method.We first find the fog area in the dark primary color map to obtain the estimated value of the transmittance using quadratic tree. Then we regard the gray-scale image after guided filtering as atmospheric light map and remove haze based on it. Box processing and image down sampling technology are also used to improve the processing speed. Finally, the atmospheric light scattering model is used to restore the image. A plenty of experiments show that algorithm is effective, efficient and has a wide range of application.

  4. Formation of grain boundaries in magnesium single crystal during equal channel angular pressing

    Czech Academy of Sciences Publication Activity Database

    Šedá, P.; Jäger, Aleš; Lejček, Pavel; Triguero, P.R.

    2014-01-01

    Roč. 94, č. 10 (2014), s. 1095-1111 ISSN 1478-6435 R&D Projects: GA ČR GBP108/12/G043; GA MŠk(CZ) LM2011026 Institutional support: RVO:68378271 Keywords : magnesium * ECAP * single crystal * EBSD * recrystallization Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.825, year: 2014

  5. Improving throughput of single-relay DF channel using linear constellation precoding

    KAUST Repository

    Fareed, Muhammad Mehboob

    2014-08-01

    In this letter, we propose a transmission scheme to improve the overall throughput of a cooperative communication system with single decode-and-forward relay. Symbol error rate and throughput analysis of the new scheme are presented to facilitate the performance comparison with the existing decode-and-forward relaying schemes. Simulation results are further provided to corroborate the analytical results. © 2012 IEEE.

  6. Simulation aided hardening of N-channel power MOSFETs to prevent single event burnout

    International Nuclear Information System (INIS)

    Dachs, C.; Palau, J.M.; Bruguier, G.; Gasiot, J.; Roubaud, F.; Tastet, P.; Calvet, M.C.; Calvel, P.

    1995-01-01

    2D MEDICI simulator is used to investigate hardening solutions to single-event burnout (SEB). SEB parametric dependencies such as carrier lifetime reduction, base enlargement, and emitter doping decrease have been verified and a p + plug modification approach for SEB hardening of power MOSFETs is validated with simulations on actual device structures

  7. Conduction channels at finite bias in single-atom gold contacts

    DEFF Research Database (Denmark)

    Brandbyge, Mads; Kobayashi, Nobuhiko; Tsukada, Masaru

    1999-01-01

    We consider the effect of a finite voltage bias on the conductance of single-atom gold contacts. We employ a nonorthogonal spn-tight-binding Hamiltonian combined with a local charge neutrality assumption. The conductance and charge distributions for finite bias are calculated using...

  8. Rutherford backscattering, nuclear reaction and channeling studies of nitrogen implanted single-crystal stainless steel

    International Nuclear Information System (INIS)

    Ferguson, M.M.; Ewan, G.T.; Mitchell, I.V.; Plattner, H.H.

    1983-01-01

    The three different methods were used to investigate a single crystal of stainless steel implanted to different doses by 40 keV 15 N 2 + ions. Conclusions are drawn on the position of nitrogen; comparison is made with implantation of deuterium and neon. (G.Q.)

  9. End-cap calorimeter performance and identification of the t-channel single top quark process with the ATLAS detector

    Science.gov (United States)

    Cojocaru, Claudiu D.

    2008-10-01

    The LHC collider will provide proton-proton collisions with 14 TeV centre of mass energy and an expected peak luminosity of 1034 cm -2s-1. ATLAS is one of the multipurpose detectors that will be used for particles detection and measurement of properties. The first part of this thesis focuses on the study of the response of the ATLAS electromagnetic and hadronic end-cap calorimeters (EMEC and HEC, respectively) in a beam test performed in the summer of 2002. For the EMEC, the dependence of the measured signal versus the beam energy was found to be linear and an electromagnetic conversion constant aEMECem = (0.446 +/- 0.009) MeV/nA was calculated. The energy resolution for the EMEC was s'Ereco Ereco = 11.8+/-0.2% GeVEre co ⊕ (0.4 +/- 0.1)%, while for the HEC it was s'Ereco Ereco = 87.7+/-0.6% GeVEre co ⊕ (3.0 +/- 0.2)%, where the reconstructed energy, Ereco, is in GeV. These results feed back into the tuning of the calorimeter Monte Carlo simulations. The second part of this thesis is on the analysis of the electroweak production of the top quark at the LHC, particularly the so-called single top t-channel, by investigating the possible isolation of signal events from the diverse background present at LHC energies. Kinematic characteristics of relevant physics objects were studied for their use as discriminant variables. After identifying these discriminants, a cut flow analysis was performed on both signal and backgrounds. It was found that the selection efficiency, epsilon (%), for the t-channel was epsilon (%) = 2.86 +/- 2.5%Stat +/- 2% TopMass +/- 5%JES +/- 5%B--tagging +/- 8%ISR/FSR +/- 2%PDF, for an integrated luminosity of 1 fb-1. For the same luminosity, a signal to background ratio (S/B) of 0.28 and a signal significance (S/ B ) of 21 were obtained. The single top production channels provide an unique opportunity to study directly properties of the top quark. These channels are also sensitive to new physics beyond the Standard Model of particle physics.

  10. Bar dynamics and channel junctions in scale-experiments of estuaries

    Science.gov (United States)

    Leuven, J.; Braat, L.; van Dijk, W. M.; Haas, T. D.; Kleinhans, M. G.

    2017-12-01

    The evolution of channels and bars in estuaries has high socio-economic relevance, with strong implications for navigation, dredging and ecology. However, the spatial and temporal evolution of channels and bars in estuaries is poorly understood. Here, we study feedbacks of bar morphodynamics on widening and narrowing of estuaries. Therefore, we conducted an experiment in a 20 m long and 3 m wide tilting flume (the 'Metronome'), in which we monitored the evolution of a self-formed estuary that developed from an intial straight channel into an irregular planform with multiple channels, braided bars and a meandering ebb channel. At locations where the estuary width is confined, major channel junctions occur, while the zones between the junctions are characterised by high braiding indices, periodically migrating channels and a relatively large estuary width. The junction locations were forced by the in- and outflow locations on the sides of the ebb-tidal delta and at the location where the channel pattern transitions from multiple channels into a single channel. In the middle of the estuary, self-confinement occurred by sedimentation on the sides of the estuary, which caused another major junction. The channel orientation at the junctions steers the morphodynamics of channels and bars immediately landward and seaward, because the orientation of inflow from the ebb-tidal delta and landward river perpetually varies. In natural systems major junction locations are mostly forced by inherited geology or human engineering. However, this study concludes that even without external forcing, the estuary planform will not converge to an ideal shape but will self-confine at major junctions and widens in the adjacent zones, resulting in an irregular planform shape.

  11. Observation method to predict meander migration and vertical degradation of rivers.

    Science.gov (United States)

    2014-05-01

    Meander migration and vertical degradation of river bed are processes that have been studied for years. : Different methods have been proposed to make predictions of the behavior of rivers with respect to these : processes. These two erosion controll...

  12. Dislocation Interactions in .gamma.-Channels between .gamma.'-Particles of Superalloy Single Crystals

    Czech Academy of Sciences Publication Activity Database

    Probst-Hein, M.; Dlouhý, Antonín; Eggeler, G.

    319-321, - (2001), s. 379-382 ISSN 0921-5093. [International Conference on the Strength of Materials /12./. Asilomar, 27.08.2000-01.09.2000] R&D Projects: GA MŠk OC P3.50 Institutional research plan: CEZ:AV0Z2041904 Keywords : discrete dislocation modeling * single crystal superalloys * .gamma./.gamma.'-interface dislocations Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.978, year: 2001

  13. Measurements of Pair Production Under Channelling Conditions by 70-180 GeV Photons Incident on Single Crystals

    CERN Multimedia

    2002-01-01

    This experiment will use the WA69 set-up to deliver a tagged photon beam in the energy range from 15~GeV to 150~GeV with a total angular spread of about @M~0.5~mrad. The incident photon direction is known to about 35~@mrad through the direction of the emitting electron. The photon beam is incident on an about 1~mm thick Ge single crystal in order to investigate pair production in single crystals. Above a certain energy threshold photons incident along crystal axis will show strongly increased pair production yi - the so-called .us Channelling Pair Production (ChPP). The produced pairs are analyzed in the @W-spectrometer. The large spread in incident photon angles offers an excellent opportunity to investigate in one single experiment the pair production in an angular region around a crystal axes and thereby compare ChPP with coherent (CPP) and incoherent (ICPP) processes. The very abrupt onset of ChPP (around threshold) will be measured and give a crucial test of the theoretical calculations. The differential...

  14. Road-Aided Ground Slowly Moving Target 2D Motion Estimation for Single-Channel Synthetic Aperture Radar

    Directory of Open Access Journals (Sweden)

    Zhirui Wang

    2016-03-01

    Full Text Available To detect and estimate ground slowly moving targets in airborne single-channel synthetic aperture radar (SAR, a road-aided ground moving target indication (GMTI algorithm is proposed in this paper. First, the road area is extracted from a focused SAR image based on radar vision. Second, after stationary clutter suppression in the range-Doppler domain, a moving target is detected and located in the image domain via the watershed method. The target’s position on the road as well as its radial velocity can be determined according to the target’s offset distance and traffic rules. Furthermore, the target’s azimuth velocity is estimated based on the road slope obtained via polynomial fitting. Compared with the traditional algorithms, the proposed method can effectively cope with slowly moving targets partly submerged in a stationary clutter spectrum. In addition, the proposed method can be easily extended to a multi-channel system to further improve the performance of clutter suppression and motion estimation. Finally, the results of numerical experiments are provided to demonstrate the effectiveness of the proposed algorithm.

  15. Monte-Carlo-calculations for the simulation of channelling-experiments with V3Si-single-crystals

    International Nuclear Information System (INIS)

    Kaufmann, R.

    1978-05-01

    The results of channelling-investigations on single-crystals of A15-type structure, like e.g. V 3 Si, are not directly comparable to analytical model-calculations. Therefore the channelling-process was simulated in a Monte-Carlo-program on the basis of the binary-collision-model. The calculated values for the minimum yield, Chisub(min), and the critical angle, Psisub(1/2), were in good agreement with the results of experiments with 2 MeV- 4 He + -particles. The lattice damage in the range of 2,000 Angstroem at the surface after an irradiation with a fluence of 6 x 10 16 - 4 He + /cm 2 at 300 KeV could be explained by normally distributed static displacements of the V-atoms with a mean value of 0.05 A. The transverse damage structure after an irradiation with a fluence of 1.5 x 10 16 - 4 He + /cm 2 at 50 KeV could be simulated by a step profile of 50% displacements of the V-atoms with a maximum value of 0.5 Angstroem at the depth of the projected range. (orig./HPOE) [de

  16. Electrophysiological Features of Single Store-Operated Calcium Channels in HEK S4 Cell Line with Stable STIM1 Protein Knockdown.

    Science.gov (United States)

    Shalygin, A V; Vigont, V A; Glushankova, L N; Zimina, O A; Kolesnikov, D O; Skopin, A Yu; Kaznacheeva, E V

    2017-07-01

    An important role in intracellular calcium signaling is played by store-operated channels activated by STIM proteins, calcium sensors of the endoplasmic reticulum. In stable STIM1 knockdown HEK S4 cells, single channels activated by depletion of intracellular calcium stores were detected by cell-attached patch-clamp technique and their electrophysiological parameters were described. Comparison of the properties of single channels in HEK293 and HEK S4 cells revealed no significant differences in their current-voltage curves, while regulation of store-operated calcium channels in these cell lines depended on the level of STIM1 expression. We can conclude that electrophysiological peculiarities of store-regulated calcium entry observed in different cells can be explained by differences in STIM1 expression.

  17. Search for Extra dimensions in a single-jet and missing energy channel at CMS experiment

    CERN Document Server

    Benucci, Leonardo

    2010-01-01

    A possible solution to the hierarchy problem is the presence of extra spatial dimensions beyond the three ones which are known from our everyday experience. The phenomenological ADD model of large extra-dimensions predicts a missing transverse energy plus a single-jet signature. This contribution addresses the sensitivity of the CMS detector at the LHC pp collider to parameters of this model, focusing on the conditions expected for second half of 2010 running (sqrt(s) = 10 TeV, O(100) pb-1). It is shown that a significant improvement of the existing limits can be obtained in such an early stage.

  18. Front-surface fabrication of moderate aspect ratio micro-channels in fused silica by single picosecond Gaussian-Bessel laser pulse

    Science.gov (United States)

    Liu, Xin; Sanner, Nicolas; Sentis, Marc; Stoian, Razvan; Zhao, Wei; Cheng, Guanghua; Utéza, Olivier

    2018-02-01

    Single-shot Gaussian-Bessel laser beams of 1 ps pulse duration and of 0.9 μm core size and 60 μm depth of focus are used for drilling micro-channels on front side of fused silica in ambient condition. Channels ablated at different pulse energies are fully characterized by AFM and post-processing polishing procedures. We identify experimental energy conditions (typically 1.5 µJ) suitable to fabricate non-tapered channels with mean diameter of 1.2 µm and length of 40 μm while maintaining an utmost quality of the front opening of the channels. In addition, by further applying accurate post-polishing procedure, channels with high surface quality and moderate aspect ratio down to a few units are accessible, which would find interest in the surface micro-structuring of materials, with perspective of further scalability to meta-material specifications.

  19. An Optimized Design of Single-Channel Beta-Gamma Coincidence Phoswich Detector by Geant4 Monte Carlo Simulations

    Directory of Open Access Journals (Sweden)

    Weihua Zhang

    2011-01-01

    Full Text Available An optimized single-channel phoswich well detector design has been proposed and assessed in order to improve beta-gamma coincidence measurement sensitivity of xenon radioisotopes. This newly designed phoswich well detector consists of a plastic beta counting cell (BC404 embedded in a CsI(Tl crystal coupled to a photomultiplier tube. The BC404 is configured in a cylindrical pipe shape to minimise light collection deterioration. The CsI(Tl crystal consists of a rectangular part and a semicylindrical scintillation part as a light reflector to increase light gathering. Compared with a PhosWatch detector, the final optimized detector geometry showed 15% improvement in the energy resolution of a 131mXe 129.4 keV conversion electron peak. The predicted beta-gamma coincidence efficiencies of xenon radioisotopes have also been improved accordingly.

  20. Joint synthetic aperture radar plus ground moving target indicator from single-channel radar using compressive sensing

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Douglas; Hallquist, Aaron; Anderson, Hyrum

    2017-10-17

    The various embodiments presented herein relate to utilizing an operational single-channel radar to collect and process synthetic aperture radar (SAR) and ground moving target indicator (GMTI) imagery from a same set of radar returns. In an embodiment, data is collected by randomly staggering a slow-time pulse repetition interval (PRI) over a SAR aperture such that a number of transmitted pulses in the SAR aperture is preserved with respect to standard SAR, but many of the pulses are spaced very closely enabling movers (e.g., targets) to be resolved, wherein a relative velocity of the movers places them outside of the SAR ground patch. The various embodiments of image reconstruction can be based on compressed sensing inversion from undersampled data, which can be solved efficiently using such techniques as Bregman iteration. The various embodiments enable high-quality SAR reconstruction, and high-quality GMTI reconstruction from the same set of radar returns.

  1. Design and Construction of an Autonomous Low-Cost Pulse Height Analyzer and a Single Channel Analyzer for Moessbauer Spectroscopy

    International Nuclear Information System (INIS)

    Velasquez, A.A.; Trujillo, J.M.; Morales, A.L.; Tobon, J.E.; Gancedo, J.R.; Reyes, L.

    2005-01-01

    A multichannel analyzer (MCA) and a single channel-analyzer (SCA) for Moessbauer spectrometry application have been designed and built. Both systems include low-cost digital and analog components. A microcontroller manages, either in PHA or MCS mode, the data acquisition, data storage and setting of the pulse discriminator limits. The user can monitor the system from an external PC through the serial port with the RS232 communication protocol. A graphic interface made with the LabVIEW software allows the user to adjust digitally the lower and upper limits of the pulse discriminator, and to visualize as well as save the PHA spectra in a file. The system has been tested using a 57Co radioactive source and several iron compounds, yielding satisfactory results. The low cost of its design, construction and maintenance make this equipment an attractive choice when assembling a Moessbauer spectrometer

  2. 3-lead acquisition using single channel ECG device developed on AD8232 analog front end for wireless ECG application

    Science.gov (United States)

    Agung, Mochammad Anugrah; Basari

    2017-02-01

    Electrocardiogram (ECG) devices measure electrical activity of the heart muscle to determine heart conditions. ECG signal quality is the key factor in determining the diseases of the heart. This paper presents the design of 3-lead acquistion on single channel wireless ECG device developed on AD8232 chip platform using microcontroller. To make the system different from others, monopole antenna 2.4 GHz is used in order to send and receive ECG signal. The results show that the system still can receive ECG signal up to 15 meters by line of sight (LOS) condition. The shape of ECG signals is precisely similar with the expected signal, although some delays occur between two consecutive pulses. For further step, the system will be applied with on-body antenna in order to investigate body to body communication that will give variation in connectivity from the others.

  3. Experimental and 2D simulation study of the single-event burnout in n-channel power MOSFETs

    International Nuclear Information System (INIS)

    Roubaud, F.; Dachs, C.; Palau, J.M.; Gasiot, J.

    1993-01-01

    The use of the 2D simulator MEDICI as a tool for Single Event Burnout (SEB) comprehension is investigated. Simulation results are compared to experimental currents induced in an N channel power MOSFET by the ions from a 252 Cf source. Current measurements have been carried out with a specially designed circuit. Simulations allow to analyze separately the effects of the ion impact and of the electrical environment parameters on the SEB phenomenon. Burnout sensitivity is found to be increased by increasing supply voltage, ion's LET and by decreasing load charge. These electrical tendencies are validated by experiments. Burnout sensitivity is also found to be sensitive to the ion impact position. The current shapes variations for given electrical parameters can be related to LET or ion impact position changes. However, some experimental current shapes are not reproduced by simulations

  4. Mixed-scale channel networks including Kingfisher-beak-shaped 3D microfunnels for efficient single particle entrapment

    Science.gov (United States)

    Lee, Yunjeong; Lim, Yeongjin; Shin, Heungjoo

    2016-06-01

    Reproducible research results for nanofluidics and their applications require viable fabrication technologies to produce nanochannels integrated with microchannels that can guide fluid flow and analytes into/out of the nanochannels. We present the simple fabrication of mixed-scale polydimethylsiloxane (PDMS) channel networks consisting of nanochannels and microchannels via a single molding process using a monolithic mixed-scale carbon mold. The monolithic carbon mold is fabricated by pyrolyzing a polymer mold patterned by photolithography. During pyrolysis, the polymer mold shrinks by ~90%, which enables nanosized carbon molds to be produced without a complex nanofabrication process. Because of the good adhesion between the polymer mold and the Si substrate, non-uniform volume reduction occurs during pyrolysis resulting in the formation of curved carbon mold side walls. These curved side walls and the relatively low surface energy of the mold provide efficient demolding of the PDMS channel networks. In addition, the trigonal prismatic shape of the polymer is converted into to a Kingfisher-beak-shaped carbon structure due to the non-uniform volume reduction. The transformation of this mold architecture produces a PDMS Kingfisher-beak-shaped 3D microfunnel that connects the microchannel and the nanochannel smoothly. The smooth reduction in the cross-sectional area of the 3D microfunnels enables efficient single microparticle trapping at the nanochannel entrance; this is beneficial for studies of cell transfection.Reproducible research results for nanofluidics and their applications require viable fabrication technologies to produce nanochannels integrated with microchannels that can guide fluid flow and analytes into/out of the nanochannels. We present the simple fabrication of mixed-scale polydimethylsiloxane (PDMS) channel networks consisting of nanochannels and microchannels via a single molding process using a monolithic mixed-scale carbon mold. The monolithic

  5. Attitude Control of a Single Tilt Tri-Rotor UAV System: Dynamic Modeling and Each Channel's Nonlinear Controllers Design

    Directory of Open Access Journals (Sweden)

    Juing-Shian Chiou

    2013-01-01

    Full Text Available This paper has implemented nonlinear control strategy for the single tilt tri-rotor aerial robot. Based on Newton-Euler’s laws, the linear and nonlinear mathematical models of tri-rotor UAVs are obtained. A numerical analysis using Newton-Raphson method is chosen for finding hovering equilibrium point. Back-stepping nonlinear controller design is based on constructing Lyapunov candidate function for closed-loop system. By imitating the linguistic logic of human thought, fuzzy logic controllers (FLCs are designed based on control rules and membership functions, which are much less rigid than the calculations computers generally perform. Effectiveness of the controllers design scheme is shown through nonlinear simulation model on each channel.

  6. Meandering worms: mechanics of undulatory burrowing in muds.

    Science.gov (United States)

    Dorgan, Kelly M; Law, Chris J; Rouse, Greg W

    2013-04-22

    Recent work has shown that muddy sediments are elastic solids through which animals extend burrows by fracture, whereas non-cohesive granular sands fluidize around some burrowers. These different mechanical responses are reflected in the morphologies and behaviours of their respective inhabitants. However, Armandia brevis, a mud-burrowing opheliid polychaete, lacks an expansible anterior consistent with fracturing mud, and instead uses undulatory movements similar to those of sandfish lizards that fluidize desert sands. Here, we show that A. brevis neither fractures nor fluidizes sediments, but instead uses a third mechanism, plastically rearranging sediment grains to create a burrow. The curvature of the undulating body fits meander geometry used to describe rivers, and changes in curvature driven by muscle contraction are similar for swimming and burrowing worms, indicating that the same gait is used in both sediments and water. Large calculated friction forces for undulatory burrowers suggest that sediment mechanics affect undulatory and peristaltic burrowers differently; undulatory burrowing may be more effective for small worms that live in sediments not compacted or cohesive enough to extend burrows by fracture.

  7. Discharge Fluctuation Effect on Meandering River Bed Evolution

    Science.gov (United States)

    Kuntjoro; Saud, Ismail; Harijanto, Didik

    2017-11-01

    This research was based on some considerations: first discharge fluctuation argued that none rivers with constant discharge and second meandering river bed evolution with considering that none of rivers in a steady state without bed change. This research developed to get formulation the relationship between fluctuations discharge with the evolution of the bottom of river considering discharge, parameter rivers and parameter sediment. In the span of daily discharge data 1997-2011 and cross section monitoring annual results 1997-2011 evolution of bottom of a river subjects obtained: Formula 1 is the relationship between discharge fluctuations with rate of sedimentation (S) and Formula 2 is the relationship between discharge fluctuations with rate of erosion (E). Thus formula have higher prediction accuracy than other published formulas and it is applicable to predict Brantas River bed evolution approximate with the real conditions. Further analysis from the output KUN-QArSHOV formula produces: Erosion equation ΔS = 25,167e0,0034 ΔQ , on constant discharge, sedimentation value occur is 25.167.10-5 meter. Sedimentation equation ΔE = 8,3455e0,0075 ΔQ , on constant discharge, erosion value occure is 8.3455.10-5 meter. Critical point between sedimentation and erosion happened on discharge between 269 m3/second and 270 m3/second

  8. Absolute determination of zero-energy phase shifts for multiparticle single-channel scattering: Generalized Levinson theorem

    International Nuclear Information System (INIS)

    Rosenberg, L.; Spruch, L.

    1996-01-01

    Levinson close-quote s theorem relates the zero-energy phase shift δ for potential scattering in a given partial wave l, by a spherically symmetric potential that falls off sufficiently rapidly, to the number of bound states of that l supported by the potential. An extension of this theorem is presented that applies to single-channel scattering by a compound system initially in its ground state. As suggested by Swan [Proc. R. Soc. London Ser. A 228, 10 (1955)], the extended theorem differs from that derived for potential scattering; even in the absence of composite bound states δ may differ from zero as a consequence of the Pauli principle. The derivation given here is based on the introduction of a continuous auxiliary open-quote open-quote length phase close-quote close-quote η, defined modulo π for l=0 by expressing the scattering length as A=acotη, where a is a characteristic length of the target. Application of the minimum principle for the scattering length determines the branch of the cotangent curve on which η lies and, by relating η to δ, an absolute determination of δ is made. The theorem is applicable, in principle, to single-channel scattering in any partial wave for e ± -atom and nucleon-nucleus systems. In addition to a knowledge of the number of composite bound states, information (which can be rather incomplete) concerning the structure of the target ground-state wave function is required for an explicit, absolute, determination of the phase shift δ. As for Levinson close-quote s original theorem for potential scattering, no additional information concerning the scattering wave function or scattering dynamics is required. copyright 1996 The American Physical Society

  9. A real-time integrator of storage-area contents for SA 40B or DIDAC 800 analyzers. Use in the digital single-channel mode

    International Nuclear Information System (INIS)

    Rigaudiere, Roger; Daburon, M.-L.

    1976-09-01

    An apparatus was developed in order to sum up, during counting, the channel contents from several storage areas of SA 40 B or DIDAC 800 multichannel analyzers. The pulse number stored in the energy bands interesting the operator are known and if necessary subsequent operation can be modified accordingly. Coupled with an autonomous amplitude encoder, this apparatus can be operated in the digital single-channel mode [fr

  10. [Clinical outcomes of single-level lumbar spondylolisthesis by minimally invasive transforaminal lumbar interbody fusion with bilateral tubular channels].

    Science.gov (United States)

    Zeng, Z L; Jia, L; Yu, Y; Xu, W; Hu, X; Zhan, X H; Jia, Y W; Wang, J J; Cheng, L M

    2017-04-01

    Objective: To evaluate the clinical effectiveness of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) for single-level lumbar spondylolisthesis treatment with bilateral Spotlight tubular channels. Methods: A total of 21 patients with lumbar spondylolisthesis whom underwent MIS-TLIF via bilateral Spotlight tubular channels were retrospectively analyzed from October 2014 to November 2015. The 21 patients included 11 males and 10 females ranged from 35 to 82 years (average aged 60.7 years). In term of spondylolisthesis category, there were 18 cases of degenerative spondylolisthesis and 3 cases of isthmic spondylolisthesis. With respect to spondylolisthesis degree, 17 cases were grade Ⅰ° and 4 cases were grade Ⅱ°. Besides, 17 cases at L(4-5) and 4 cases at L(5)-S(1)were categorized by spondylolisthesis levels. Operation duration, blood loss, postoperative drainage and intraoperative exposure time were recorded, functional improvement was defined as an improvement in the Oswestry Disability Index (ODI), Visual Analog Scale (VAS) was also employed at pre and post-operation (3 months and the last follow-up), to evaluate low back and leg pain. Furthermore, to evaluate the recovery of the intervertebral foramen and of lumbar sagittal curvature, average height of intervertebral space, Cobb angles of lumbar vertebrae and operative segments, spondylolisthesis index were measured. At the last follow-up, intervertebral fusion was assessed using Siepe evaluation criteria and the clinical outcome was assessed using the MacNab scale. Radiographic and functional outcomes were compared pre- and post-operation using the paired T test to determine the effectiveness of MIS-TLIF. Statistical significance was defined as P spondylolisthesis incidence ( t =17.1, P spondylolisthesis incidence ( t =18.6, P spondylolisthesis vertebrae were restored completely. Lastly, at the last follow-up, 12 cases of grade 1 and 7 cases of grade 2 fusion were present as determined

  11. Linear Regression on Sparse Features for Single-Channel Speech Separation

    DEFF Research Database (Denmark)

    Schmidt, Mikkel N.; Olsson, Rasmus Kongsgaard

    2007-01-01

    In this work we address the problem of separating multiple speakers from a single microphone recording. We formulate a linear regression model for estimating each speaker based on features derived from the mixture. The employed feature representation is a sparse, non-negative encoding of the speech...... compared to linear regression on spectral features and compared to separation based directly on the non-negative sparse features....... mixture in terms of pre-learned speaker-dependent dictionaries. Previous work has shown that this feature representation by itself provides some degree of separation. We show that the performance is significantly improved when regression analysis is performed on the sparse, non-negative features, both...

  12. Demonstration of 5.1 Tbit/s data capacity on a single-wavelength channel

    DEFF Research Database (Denmark)

    Mulvad, Hans Christian Hansen; Galili, Michael; Oxenløwe, Leif Katsuo

    2010-01-01

    We have generated a single-wavelength data signal with a data capacity of 5.1 Tbit/s. The enabling techniques to generate the data signal are optical time-division multiplexing up to a symbol rate of 1.28 Tbaud, differential quadrature phase shift keying as data format, and polarisation......-multiplexing. For the first time, error-free performance with a bit error rate less than 1e-9 is demonstrated for the 5.1 Tbit/s data signal. This is achieved in a back-to-back configuration using a direct detection receiver based on polarisation- and time-demultiplexing, delay-demodulation and balanced photo-detection....

  13. Demonstration of 5.1 Tbit/s data capacity on a single-wavelength channel.

    Science.gov (United States)

    Hansen Mulvad, Hans Christian; Galili, Michael; Oxenløwe, Leif K; Hu, Hao; Clausen, Anders T; Jensen, Jesper B; Peucheret, Christophe; Jeppesen, Palle

    2010-01-18

    We have generated a single-wavelength data signal with a data capacity of 5.1 Tbit/s. The enabling techniques to generate the data signal are optical time-division multiplexing up to a symbol rate of 1.28 Tbaud, differential quadrature phase shift keying as data format, and polarisation-multiplexing. For the first time, error-free performance with a bit error rate less than 10(-9) is demonstrated for the 5.1 Tbit/s data signal. This is achieved in a back-to-back configuration using a direct detection receiver based on polarisation- and time-demultiplexing, delay-demodulation and balanced photo-detection.

  14. Single-Channel Speech Separation using Sparse Non-Negative Matrix Factorization

    DEFF Research Database (Denmark)

    Schmidt, Mikkel N.; Olsson, Rasmus Kongsgaard

    2007-01-01

    We apply machine learning techniques to the problem of separating multiple speech sources from a single microphone recording. The method of choice is a sparse non-negative matrix factorization algorithm, which in an unsupervised manner can learn sparse representations of the data. This is applied....... The performance of the unsupervised and supervised adaptation schemes result in significant improvements in terms of the target-to-masker ratio....... to the learning of personalized dictionaries from a speech corpus, which in turn are used to separate the audio stream into its components. We show that computational savings can be achieved by segmenting the training data on a phoneme level. To split the data, a conventional speech recognizer is used...

  15. ddpcRquant: threshold determination for single channel droplet digital PCR experiments.

    Science.gov (United States)

    Trypsteen, Wim; Vynck, Matthijs; De Neve, Jan; Bonczkowski, Pawel; Kiselinova, Maja; Malatinkova, Eva; Vervisch, Karen; Thas, Olivier; Vandekerckhove, Linos; De Spiegelaere, Ward

    2015-07-01

    Digital PCR is rapidly gaining interest in the field of molecular biology for absolute quantification of nucleic acids. However, the first generation of platforms still needs careful validation and requires a specific methodology for data analysis to distinguish negative from positive signals by defining a threshold value. The currently described methods to assess droplet digital PCR (ddPCR) are based on an underlying assumption that the fluorescent signal of droplets is normally distributed. We show that this normality assumption does not likely hold true for most ddPCR runs, resulting in an erroneous threshold. We suggest a methodology that does not make any assumptions about the distribution of the fluorescence readouts. A threshold is estimated by modelling the extreme values in the negative droplet population using extreme value theory. Furthermore, the method takes shifts in baseline fluorescence between samples into account. An R implementation of our method is available, allowing automated threshold determination for absolute ddPCR quantification using a single fluorescent reporter.

  16. A Maximum Likelihood Estimation of Vocal-Tract-Related Filter Characteristics for Single Channel Speech Separation

    Directory of Open Access Journals (Sweden)

    Dansereau Richard M

    2007-01-01

    Full Text Available We present a new technique for separating two speech signals from a single recording. The proposed method bridges the gap between underdetermined blind source separation techniques and those techniques that model the human auditory system, that is, computational auditory scene analysis (CASA. For this purpose, we decompose the speech signal into the excitation signal and the vocal-tract-related filter and then estimate the components from the mixed speech using a hybrid model. We first express the probability density function (PDF of the mixed speech's log spectral vectors in terms of the PDFs of the underlying speech signal's vocal-tract-related filters. Then, the mean vectors of PDFs of the vocal-tract-related filters are obtained using a maximum likelihood estimator given the mixed signal. Finally, the estimated vocal-tract-related filters along with the extracted fundamental frequencies are used to reconstruct estimates of the individual speech signals. The proposed technique effectively adds vocal-tract-related filter characteristics as a new cue to CASA models using a new grouping technique based on an underdetermined blind source separation. We compare our model with both an underdetermined blind source separation and a CASA method. The experimental results show that our model outperforms both techniques in terms of SNR improvement and the percentage of crosstalk suppression.

  17. A Maximum Likelihood Estimation of Vocal-Tract-Related Filter Characteristics for Single Channel Speech Separation

    Directory of Open Access Journals (Sweden)

    Mohammad H. Radfar

    2006-11-01

    Full Text Available We present a new technique for separating two speech signals from a single recording. The proposed method bridges the gap between underdetermined blind source separation techniques and those techniques that model the human auditory system, that is, computational auditory scene analysis (CASA. For this purpose, we decompose the speech signal into the excitation signal and the vocal-tract-related filter and then estimate the components from the mixed speech using a hybrid model. We first express the probability density function (PDF of the mixed speech's log spectral vectors in terms of the PDFs of the underlying speech signal's vocal-tract-related filters. Then, the mean vectors of PDFs of the vocal-tract-related filters are obtained using a maximum likelihood estimator given the mixed signal. Finally, the estimated vocal-tract-related filters along with the extracted fundamental frequencies are used to reconstruct estimates of the individual speech signals. The proposed technique effectively adds vocal-tract-related filter characteristics as a new cue to CASA models using a new grouping technique based on an underdetermined blind source separation. We compare our model with both an underdetermined blind source separation and a CASA method. The experimental results show that our model outperforms both techniques in terms of SNR improvement and the percentage of crosstalk suppression.

  18. Initial Results of Accelerated Stress Testing on Single-Channel and Multichannel Drivers: Solid-State Lighting Technology Area

    Energy Technology Data Exchange (ETDEWEB)

    None

    2018-02-28

    This report is the first in a series of studies on accelerated stress testing (AST) of drivers used for SSL luminaires, such as downlights, troffers, and streetlights. A representative group of two-stage commercial driver products was exposed to an AST environment consisting of 75°C and 75% relative humidity (7575). These drivers were a mix of single-channel drivers (i.e., a single output current for one LED primary) and multichannel drivers (i.e., separate output currents for multiple LED primaries). This AST environment was chosen because previous testing on downlights with integrated drivers demonstrated that 38% of the sample population failed in less than 2,500 hours of testing using this method. In addition to AST test results, the performance of an SSL downlight product incorporating an integrated, multichannel driver during extended room temperature operational life (RTOL) testing is also reported. A battery of measurements was used to evaluate these products during accelerated testing, including full electrical characterization (i.e., power consumption, PF, total harmonic distortion [THD], and inrush current) and photometric characterization of external LED loads attached to the drivers (i.e., flicker performance and lumen maintenance).

  19. Insertion of linear 8.4 μm diameter 16 channel carbon fiber electrode arrays for single unit recordings

    Science.gov (United States)

    Patel, Paras R.; Na, Kyounghwan; Zhang, Huanan; Kozai, Takashi D. Y.; Kotov, Nicholas A.; Yoon, Euisik; Chestek, Cynthia A.

    2016-01-01

    Objective Single carbon fiber electrodes (d=8.4 μm) insulated with parylene-c and functionalized with PEDOT:pTS have been shown to record single unit activity but manual implantation of these devices with forceps can be difficult. Without an improvement in the insertion method any increase in the channel count by fabricating carbon fiber arrays would be impractical. In this study, we utilize a water soluble coating and structural backbones that allow us to create, implant, and record from fully functionalized arrays of carbon fibers with ~150 μm pitch. Approach Two approaches were tested for the insertion of carbon fiber arrays. The first method used a PEG coating that temporarily stiffened the fibers while leaving a small portion at the tip exposed. The small exposed portion (500 μm – 1 mm) readily penetrated the brain allowing for an insertion that did not require the handling of each fiber by forceps. The second method involved the fabrication of silicon support structures with individual shanks spaced 150 μm apart. Each shank consisted of a small groove that held an individual carbon fiber. Main results Our results showed that the PEG coating allowed for the chronic implantation of carbon fiber arrays in 5 rats with unit activity detected at 31 days post-implant. The silicon support structures recorded single unit activity in 3 acute rat surgeries. In one of those surgeries a stacked device with 3 layers of silicon support structures and carbon fibers was built and shown to readily insert into the brain with unit activity on select sites. Significance From these studies we have found that carbon fibers spaced at ~150 μm readily insert into the brain. This greatly increases the recording density of chronic neural probes and paves the way for even higher density devices that have a minimal scarring response. PMID:26035638

  20. RBS/channeling analysis of hydrogen-implanted single crystals of FZ silicon and 6H silicon

    International Nuclear Information System (INIS)

    Irwin, R.B.

    1984-01-01

    Single crystals of FZ silicon and 6H silicon carbide were implanted with hydrogen ions (50 and 80 keV, respectively) to fluences from 2 x 10 16 H + /cm 2 to 2 x 10 18 H+/cm 2 . The implantations were carried out at three temperatures: approx.95K, 300 K, and approx.800 K. Swelling of the samples was measured by surface profilometry. RBS/channeling was used to obtain the damage profiles and to determine the amount of hydrogen retained in the lattice. The damage profiles are centered around X/sub m/ for the implants into silicon and around R/sub p/ for silicon carbide. For silicon carbide implanted at 95 K and 300 K and for silicon implanted at 95 K, the peak damage region is amorphous for fluences above 8 x 10 16 H + /cm 2 , 4 x 10 17 H + /cm 2 , and 2 x 10 17 H + /cm 2 , respectively. Silicon implanted at 300 and 800 K and silicon carbide implanted at 800 K remain crystalline up to fluences of 1 x 10 18 H + /cm 2 . The channeling damage results agree with previously reported TEM and electron diffraction data. The predictions of a simple disorder-accumulation model with a linear annealing term explains qualitatively the observed damage profiles in silicon carbide. Quantitatively, however, the model predicts faster development of the damage profiles than is observed at low fluences in both silicon and silicon carbide. For samples implanted at 300 and 800 K, the model also predicts substantially less peak disorder than is observed. The effect of the surface, the retained hydrogen, the shape of S/sub D/(X), and the need for a nonlinear annealing term may be responsible for the discrepancy

  1. Influence of large wood on channel hydraulics, sediment (dis-)connectivity and channel morphology in a medium-sized mixed-load Austrian stream

    Science.gov (United States)

    Schuchardt, Anne; Pöppl, Ronald; Morche, David

    2017-04-01

    It is widely known that large wood (LW) in rivers alters channel hydraulics, channel morphology and sediment transport. Channel spanning LW can create blocking barriers, steps and dams which store sediment and organic material in small reservoirs for the lifetime of the damming structure. Otherwise, the breach of LW key logs and jams makes the long term stored sediment available for fluvial transport. However, detailed field measurements on the distribution of LW and its influence on hydraulic variables, channel morphology and (especially) sediment connectivity are still rare, thus further constituting the major aim of this study. The study was performed along the lower reaches ( 6 km) of the Fugnitz River, a mixed-load, medium-sized (catchment area 130 km2) single-thread perennial stream, located in the Bohemian Massif, Austria. The spatial distribution and characterization of LW (>1 m in length and >10 cm in diameter) was examined along the main stem via field mapping and dGPS measurements. Hydraulic channel parameters (e.g. channel gradient, cross-sectional profiles) and volumes of retained sediment were determined via field measurements, while channel morphology incl. indications of LW-induced geomorphic processes (e.g. bank undercutting, scouring) was obtained via geomorphic mapping. Flow characteristics and bed load transport rates were measured using an Ott-Nautilus and a portable Helley-Smith bed load sampler during different water stages. Additionally, bed sediment textures were examined by performing pebble count analyses. In-channel LW accumulations (total volume of 588 m3) were primarily observed in meandering river reaches as well as in reaches with steep hillslopes. 36% of all LW accumulations were classified as dams, steps or deflectors altering flow conditions or creating backwater areas decreasing sediment connectivity. Highest volumes of sediment storage (total volume of 26 m3) have been primarily recorded at locations where bank erosion processes

  2. Exploring pre-channelization bar and planform dynamics of a large regulated Alpine River

    Science.gov (United States)

    Zen, Simone; Zolezzi, Guido; Scorpio, Vittoria; Mastronunzio, Marco; Bertoldi, Walter; Comiti, Francesco; Daiprà, Elena

    2017-04-01

    As a consequence of heavy channelization mostly carried out in the 1800s, the planform and bars morphodynamics of many large European rivers is hardly detectable even from aerial images dating back several decades, because of the marked reduction of the channel width and of the related morphological complexity. However, when available, historical maps can provide quantitative information on the morphology that characterized these rivers before massive human intervention occurred. In this work we focus on a 100 km reach of the Adige - Etsch River, NE, Italy, with the aim of exploring the short-term (some decades) morphological dynamics that might have characterized the pre-channelized river bed and planform in its single-thread reaches before heavy human intervention. To this aim we integrate the application of a morphodynamic analytical model for meandering rivers with irregularly varying curvature and channel width with the multi-temporal analysis of pre-channelization historical maps. The work focuses on the sinuous and meandering reaches once characterized by spatially varying channel width, and presence of alternate, point and mid-channel bars. Challenges in such kind of integrated analysis are posed by the reconstruction of channel - forming streamflow values and of sediment size that may have characterized the river reaches up to nearly three centuries ago prior to heavy regulation. Formative discharge ranges have been obtained as those generating the best geometrical fit between the modeled river bed morphology and the one observed from the maps. Once calibrated by this procedure, the model was fed through the estimated discharge value to compute the longitudinal variability of the outer-bank shear stress, as a proxy for the locations potentially affected by fluvial bank erosion. The historical maps reveal that during the 17th and 18th century, before the massive channelization, the river morphodynamics was already far from being "natural", especially

  3. Why do they keep calling? Single parents’ Domestication of mandatory e-government self-service channels

    DEFF Research Database (Denmark)

    Østergaard Madsen, Christian

    The Danish Digitization strategy 2011-2015 made e-government channels mandatory within multiple areas, including public benefits. Although most Danes have adopted the e-government channels, many keep using traditional channels. Moreover, some have their own ways of interpreting and using the e-government...... other, to claim economic benefits. The thesis positions itself within channel choice studies in the e-government research field. It contributes to this literature by studying citizens’ actual use of e-government and traditional channels in a post-adoption and mandatory setting. It applies Domestication...

  4. Extracting time-frequency feature of single-channel vastus medialis EMG signals for knee exercise pattern recognition.

    Science.gov (United States)

    Zhang, Yi; Li, Peiyang; Zhu, Xuyang; Su, Steven W; Guo, Qing; Xu, Peng; Yao, Dezhong

    2017-01-01

    The EMG signal indicates the electrophysiological response to daily living of activities, particularly to lower-limb knee exercises. Literature reports have shown numerous benefits of the Wavelet analysis in EMG feature extraction for pattern recognition. However, its application to typical knee exercises when using only a single EMG channel is limited. In this study, three types of knee exercises, i.e., flexion of the leg up (standing), hip extension from a sitting position (sitting) and gait (walking) are investigated from 14 healthy untrained subjects, while EMG signals from the muscle group of vastus medialis and the goniometer on the knee joint of the detected leg are synchronously monitored and recorded. Four types of lower-limb motions including standing, sitting, stance phase of walking, and swing phase of walking, are segmented. The Wavelet Transform (WT) based Singular Value Decomposition (SVD) approach is proposed for the classification of four lower-limb motions using a single-channel EMG signal from the muscle group of vastus medialis. Based on lower-limb motions from all subjects, the combination of five-level wavelet decomposition and SVD is used to comprise the feature vector. The Support Vector Machine (SVM) is then configured to build a multiple-subject classifier for which the subject independent accuracy will be given across all subjects for the classification of four types of lower-limb motions. In order to effectively indicate the classification performance, EMG features from time-domain (e.g., Mean Absolute Value (MAV), Root-Mean-Square (RMS), integrated EMG (iEMG), Zero Crossing (ZC)) and frequency-domain (e.g., Mean Frequency (MNF) and Median Frequency (MDF)) are also used to classify lower-limb motions. The five-fold cross validation is performed and it repeats fifty times in order to acquire the robust subject independent accuracy. Results show that the proposed WT-based SVD approach has the classification accuracy of 91.85%±0.88% which

  5. Extracting time-frequency feature of single-channel vastus medialis EMG signals for knee exercise pattern recognition.

    Directory of Open Access Journals (Sweden)

    Yi Zhang

    Full Text Available The EMG signal indicates the electrophysiological response to daily living of activities, particularly to lower-limb knee exercises. Literature reports have shown numerous benefits of the Wavelet analysis in EMG feature extraction for pattern recognition. However, its application to typical knee exercises when using only a single EMG channel is limited. In this study, three types of knee exercises, i.e., flexion of the leg up (standing, hip extension from a sitting position (sitting and gait (walking are investigated from 14 healthy untrained subjects, while EMG signals from the muscle group of vastus medialis and the goniometer on the knee joint of the detected leg are synchronously monitored and recorded. Four types of lower-limb motions including standing, sitting, stance phase of walking, and swing phase of walking, are segmented. The Wavelet Transform (WT based Singular Value Decomposition (SVD approach is proposed for the classification of four lower-limb motions using a single-channel EMG signal from the muscle group of vastus medialis. Based on lower-limb motions from all subjects, the combination of five-level wavelet decomposition and SVD is used to comprise the feature vector. The Support Vector Machine (SVM is then configured to build a multiple-subject classifier for which the subject independent accuracy will be given across all subjects for the classification of four types of lower-limb motions. In order to effectively indicate the classification performance, EMG features from time-domain (e.g., Mean Absolute Value (MAV, Root-Mean-Square (RMS, integrated EMG (iEMG, Zero Crossing (ZC and frequency-domain (e.g., Mean Frequency (MNF and Median Frequency (MDF are also used to classify lower-limb motions. The five-fold cross validation is performed and it repeats fifty times in order to acquire the robust subject independent accuracy. Results show that the proposed WT-based SVD approach has the classification accuracy of 91.85%±0

  6. Vertical evolution of wind meandering in a nocturnal boundary layer during low-wind speed conditions

    Science.gov (United States)

    Stefanello, Michel; Acevedo, Otávio; Mortarini, Luca; Cava, Daniela; Giostra, Umberto; Degrazia, Gervásio; Anfossi, Domenico

    2017-04-01

    In the nocturnal boundary layer episodes of horizontal wind meandering are frequent. These episodes are characterised by low-wind regimes (wind speed less than 1.5 m s-1) in which submeso motions drive the wind dynamics and turbulence is weak and often intermittent. The inception of the meandering phenomenon as well as the interaction between turbulence and the submeso oscillations are still poorly understood. In this work we study the vertical evolution of the wind meandering by analysingnight-time anemometric data. The observations were carried on at a coastal site in Espirito Santo state, south-eastern Brazil from august to November 2016. The turbulent data, divided in hourly series, were collected in a 140-m tower designed to provide micrometeorological observations with high vertical resolution and deep coverage of the lower portion of the atmospheric boundary layer. Particularly, turbulence observations of the wind components and temperature are carried at 11 vertical levels. The tower has been deployed next to a natural gas power plant, at 3 km from the ocean. The terrain is generally flat for an area of 30 km from the tower, where moderate hills exist. The meandering timescale at each level is evaluated through the Eulerian Autocorrelation Functions of the horizontal wind velocity components and temperature, while the interactions between the different scales of motions is studied using the multi-correlation analysis. Thus the vertical evolution of meandering and time scales structure can be studied.

  7. Coupling MAST-1D, a sediment routing model for channel-floodplain complexes, with channel migration relationships to predict reach-averaged river morphodynamics. Preliminary results

    Science.gov (United States)

    Viparelli, E.; Eke, E. C.; Lauer, J. W.

    2017-12-01

    Sediment exchange between the channel and floodplain can occur via meander migration, overbank deposition or erosion, and changes in channel geometry. Depending on channel and floodplain history, floodplains can act either as sources or sinks of bed material and/or wash load. Here we present preliminary modeling results that explicitly account for the feedbacks between the changes in floodplain geometry and sediment size distribution and the changes in channel geometry and migration. These results are obtained by coupling the Morphodynamics And Sediment Tracers in 1D (MAST-1D) program with the results of meander migration studies linking the bankfull flow depth and mean velocity to channel migration, sinuosity and channel geometry. MAST-1D is a numerical model built to describe grain size specific transport of sediment and tracers and the long-term - i.e. decadal and longer - evolution of channel floodplain complexes. MAST-1D differs from other 1D numerical models because it allows for 1) uneven exchange of sediment and tracers between the river channel and the floodplain, 2) temporal changes in channel geometry, bed elevation and floodplain thickness, which result in changes in the channel hydraulic capacity, and 3) temporal changes of size distribution and tracer content in the floodplain, in the load and in the underlying substrate. Under conditions of constant base level, water and sediment supply, the system evolves toward a steady state wherein the amount of sediment deposited through point bar deposition and overbank sedimentation is balanced by the erosion of sediment from the floodplain through lateral migration. The current formulation couples MAST-1D with empirical channel migration relationships that link bankfull flow depth and mean velocity to channel migration, sinuosity and channel geometry. Future development of this preliminary work will involve a fully coupled MAST-1D model with a standard meander migration model that will allow for the building

  8. Assessment of long-term channel changes in the Mekong River using remote sensing and a channel-evolution model

    Science.gov (United States)

    Miyazawa, N.

    2011-12-01

    River-channel changes are a key factor affecting physical, ecological and management issues in the fluvial environment. In this study, long-term channel changes in the Mekong River were assessed using remote sensing and a channel-evolution model. A channel-evolution model for calculating long-term channel changes of a measndering river was developed using a previous fluid-dynamic model [Zolezzi and Seminara, 2001], and was applied in order to quantify channel changes of two meandering reaches in the Mekong River. Quite few attempts have been made so far to combine remote sensing observation of meandering planform change with the application of channel evolution models within relatively small-scale gravel-bed systems in humid temperate regions. The novel point of the present work is to link state-of-art meandering planform evolution model with observed morphological changes within large-scale sand-bed rivers with higher bank height in tropical monsoonal climate regions, which are the highly dynamic system, and assess the performance. Unstable extents of the reaches could be historically identified using remote-sensing technique. The instability caused i) bank erosion and accretion of meander bends and ii) movement or development of bars and changes in the flow around the bars. The remote sensing measurements indicate that maximum erosion occurred downstream of the maximum curvature of the river-center line in both reaches. The model simulations indicates that under the mean annual peak discharge the maximum of excess longitudinal velocity near the banks occurs downstream of the maximum curvature in both reaches. The channel migration coefficients of the reaches were calibrated by comparing remote-sensing measurements and model simulations. The diffrence in the migration coefficients between both reaches depends on the diffrence in bank height rather than the geotechnical properties of floodplain sediments. Possible eroded floodplain areas and accreted floodplain

  9. Assembly of disperse red 1 molecules in the channels of AlPO4-5 single crystals for second-harmonic generation

    NARCIS (Netherlands)

    Jiang, FY; Lu, WX; Zhai, JP; Ye, JT; Wong, GKL; Han, Xueyao; Tang, ZK

    2006-01-01

    Disperse red 1 (DR1) molecules have been successfully incorporated into the one-dimensional channels of AlPO4-5 single crystals by means of vapor-phase diffusion. Polarizing microscope and SHG results indicate that the DR1 molecules are well aligned in a preferred direction along the crystal

  10. Validation of the Dynamic Wake Meander model with focus on tower loads

    Science.gov (United States)

    Larsen, T. J.; Larsen, G. C.; Pedersen, M. M.; Enevoldsen, K.; Madsen, H. A.

    2017-05-01

    This paper presents a comparison between measured and simulated tower loads for the Danish offshore wind farm Nysted 2. Previously, only limited full scale experimental data containing tower load measurements have been published, and in many cases the measurements include only a limited range of wind speeds. In general, tower loads in wake conditions are very challenging to predict correctly in simulations. The Nysted project offers an improved insight to this field as six wind turbines located in the Nysted II wind farm have been instrumented to measure tower top and tower bottom moments. All recorded structural data have been organized in a database, which in addition contains relevant wind turbine SCADA data as well as relevant meteorological data - e.g. wind speed and wind direction - from an offshore mast located in the immediate vicinity of the wind farm. The database contains data from a period extending over a time span of more than 3 years. Based on the recorded data basic mechanisms driving the increased loading experienced by wind turbines operating in offshore wind farm conditions have been identified, characterized and modeled. The modeling is based on the Dynamic Wake Meandering (DWM) approach in combination with the state-of-the-art aeroelastic model HAWC2, and has previously as well as in this study shown good agreement with the measurements. The conclusions from the study have several parts. In general the tower bending and yaw loads show a good agreement between measurements and simulations. However, there are situations that are still difficult to match. One is tower loads of single-wake operation near rated ambient wind speed for single wake situations for spacing’s around 7-8D. A specific target of the study was to investigate whether the largest tower fatigue loads are associated with a certain downstream distance. This has been identified in both simulations and measurements, though a rather flat optimum is seen in the measurements.

  11. Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse

    Directory of Open Access Journals (Sweden)

    Vandewauw Ine

    2013-02-01

    Full Text Available Abstract Background Somatosensory nerve fibres arising from cell bodies within the trigeminal ganglia (TG in the head and from a string of dorsal root ganglia (DRG located lateral to the spinal cord convey endogenous and environmental stimuli to the central nervous system. Although several members of the transient receptor potential (TRP superfamily of cation channels have been implicated in somatosensation, the expression levels of TRP channel genes in the individual sensory ganglia have never been systematically studied. Results Here, we used quantitative real-time PCR to analyse and compare mRNA expression of all TRP channels in TG and individual DRGs from 27 anatomically defined segments of the spinal cord of the mouse. At the mRNA level, 17 of the 28 TRP channel genes, TRPA1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPM3, TRPM4, TRPM5, TRPM6, TRPM7, TRPM8, TRPV1, TRPV2, TRPV4, TRPML1 and TRPP2, were detectable in every tested ganglion. Notably, four TRP channels, TRPC4, TRPM4, TRPM8 and TRPV1, showed statistically significant variation in mRNA levels between DRGs from different segments, suggesting ganglion-specific regulation of TRP channel gene expression. These ganglion-to-ganglion differences in TRP channel transcript levels may contribute to the variability in sensory responses in functional studies. Conclusions We developed, compared and refined techniques to quantitatively analyse the relative mRNA expression of all TRP channel genes at the single ganglion level. This study also provides for the first time a comparative mRNA distribution profile in TG and DRG along the entire vertebral column for the mammalian TRP channel family.

  12. Measurement of the t-channel single top-quark cross section at 13 TeV

    CERN Document Server

    CMS Collaboration

    2015-01-01

    A measurement of the $t$-channel single top-quark cross section is performed using the very first LHC proton-proton collisions at 13 TeV with the CMS detector. The dataset corresponds to an integrated luminosity of $42\\,\\,\\rm pb^{-1}$. Events are selected with one muon in the final state. The signal is extracted from a fit to the pseudo-rapidity distribution of the recoiling jet. The inclusive cross section is measured to be $\\sigma_{t-\\rm ch}=274\\pm 98\\,{\\rm (stat.)} \\pm 52\\,{\\rm (syst.)}\\pm 33\\,{\\rm (lumi.)}$. The observed (expected) significance of the signal contribution is 3.5 (2.7) standard deviations with respect to the background-only hypothesis. The magnitude of the CKM matrix element $V_{\\mathrm{tb}}$ is also calculated, yielding $|V_{\\mathrm{tb}}|=1.12\\pm0.24\\,{\\rm (exp.)}\\pm0.02\\,{\\rm (theo.)}$. The results are found to be in agreement with predictions by the standard model.

  13. Single-channel 40 Gbit/s digital coherent QAM quantum noise stream cipher transmission over 480 km.

    Science.gov (United States)

    Yoshida, Masato; Hirooka, Toshihiko; Kasai, Keisuke; Nakazawa, Masataka

    2016-01-11

    We demonstrate the first 40 Gbit/s single-channel polarization-multiplexed, 5 Gsymbol/s, 16 QAM quantum noise stream cipher (QNSC) transmission over 480 km by incorporating ASE quantum noise from EDFAs as well as the quantum shot noise of the coherent state with multiple photons for the random masking of data. By using a multi-bit encoded scheme and digital coherent transmission techniques, secure optical communication with a record data capacity and transmission distance has been successfully realized. In this system, the signal level received by Eve is hidden by both the amplitude and the phase noise. The highest number of masked signals, 7.5 x 10(4), was achieved by using a QAM scheme with FEC, which makes it possible to reduce the output power from the transmitter while maintaining an error free condition for Bob. We have newly measured the noise distribution around I and Q encrypted data and shown experimentally with a data size of as large as 2(25) that the noise has a Gaussian distribution with no correlations. This distribution is suitable for the random masking of data.

  14. Ultra-wide tuning single channel filter based on one-dimensional photonic crystal with an air cavity

    Science.gov (United States)

    Zhao, Xiaodan; Yang, Yibiao; Chen, Zhihui; Wang, Yuncai; Fei, Hongming; Deng, Xiao

    2017-02-01

    By inserting an air cavity into a one-dimensional photonic crystal of LiF/GaSb, a tunable filter covering the whole visible range is proposed. Following consideration of the dispersion of the materials, through modulating the thickness of the air cavity, we demonstrate that a single resonant peak can shift from 416.1 to 667.3 nm in the band gap at normal incidence by means of the transfer matrix method. The research also shows that the transmittance of the channel can be maximized when the number of periodic LiF/GaSb layers on one side of the air defect layer is equal to that of the other side. When adding a period to both sides respectively, the full width at half maximum of the defect mode is reduced by one order of magnitude. This structure will provide a promising approach to fabricate practical tunable filters in the visible region with ultra-wide tuning range. Project supported by the National Natural Science Foundation of China (Nos. 61575138, 61307069, 51205273), and the Top Young Academic Leaders and the Outstanding Innovative Teams of Higher Learning Institutions of Shanxi.

  15. An ultrasensitive squamous cell carcinoma antigen biosensing platform utilizing double-antibody single-channel amplification strategy.

    Science.gov (United States)

    Ren, Xiang; Wu, Dan; Wang, Yuhuan; Zhang, Yunhui; Fan, Dawei; Pang, Xuehui; Li, Yueyun; Du, Bin; Wei, Qin

    2015-10-15

    A novel electrochemical immunosensor was developed for ultrasensitive detection of squamous cell carcinoma antigen (SCCA), which was based on the double-antibody single-channel amplification strategy. For the first time, human immunoglobulin antibody (anti-HIgG) was used as the supporting framework to amplify the loading quantity of SCCA antibody (anti-SCCA). In this strategy, SCCA can be detected without using mesoporous nanometers to amplify the signal. In addition, Pd icosahedrons were first used as the connecter to immobilize the antibodies and strengthen the sensitivity. Only one touch point exists under the limited condition between a sphere and another shape in geometry, thus the Pd icosahedron is an excellent candidate as the role of connecter. Gold nanoparticles (Au NPs) decorated with mercapto-functionalized graphene sheets (Au@GS) were synthesized as the transducing materials. The fabricated immunosensor exhibited an excellent detection limit of 2.8 pg/mL and wide linear range of 0.01-5 ng/mL. This kind of immunosensor would provide a potential application in clinical diagnosis. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Sequential Total Variation Denoising for the Extraction of Fetal ECG from Single-Channel Maternal Abdominal ECG.

    Science.gov (United States)

    Lee, Kwang Jin; Lee, Boreom

    2016-07-01

    Fetal heart rate (FHR) is an important determinant of fetal health. Cardiotocography (CTG) is widely used for measuring the FHR in the clinical field. However, fetal movement and blood flow through the maternal blood vessels can critically influence Doppler ultrasound signals. Moreover, CTG is not suitable for long-term monitoring. Therefore, researchers have been developing algorithms to estimate the FHR using electrocardiograms (ECGs) from the abdomen of pregnant women. However, separating the weak fetal ECG signal from the abdominal ECG signal is a challenging problem. In this paper, we propose a method for estimating the FHR using sequential total variation denoising and compare its performance with that of other single-channel fetal ECG extraction methods via simulation using the Fetal ECG Synthetic Database (FECGSYNDB). Moreover, we used real data from PhysioNet fetal ECG databases for the evaluation of the algorithm performance. The R-peak detection rate is calculated to evaluate the performance of our algorithm. Our approach could not only separate the fetal ECG signals from the abdominal ECG signals but also accurately estimate the FHR.

  17. Cross section measurement of t-channel single top quark production in pp collisions at s=13TeV

    Directory of Open Access Journals (Sweden)

    A.M. Sirunyan

    2017-09-01

    Full Text Available The cross section for the production of single top quarks in the t channel is measured in proton–proton collisions at 13TeV with the CMS detector at the LHC. The analyzed data correspond to an integrated luminosity of 2.2fb−1. The event selection requires one muon and two jets where one of the jets is identified as originating from a bottom quark. Several kinematic variables are then combined into a multivariate discriminator to distinguish signal from background events. A fit to the distribution of the discriminating variable yields a total cross section of 238±13(stat±29(syst pb and a ratio of top quark and top antiquark production of Rt-ch.=1.81±0.18(stat±0.15(syst. From the total cross section the absolute value of the CKM matrix element Vtb is calculated to be 1.05±0.07(exp±0.02(theo. All results are in agreement with the standard model predictions.

  18. Measurement of s-channel single top-quark production with the ATLAS detector using total event likelihoods

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00333614

    2016-09-21

    A measurement of s-channel single top-quark production in proton-proton collisions at a centre-of-mass energy of $8\\,\\mathrm{TeV}$ is presented. The dataset has been recorded with the ATLAS detector at the LHC and corresponds to an integrated luminosity of 20.3$\\,\\mathrm{fb}^{−1}$. Collision events are selected so that a subset of the data is obtained where the signal fraction is relatively high. Selected events contain one isolated electron or muon, missing transverse momentum and 2 jets, both of which are induced by b-quarks. All of these objects have large transverse momenta. The resulting set of events is still dominated by background processes, most notably top-quark pair production and the production of W-bosons in association with jets. In order to further separate the signal from the backgrounds, several approximate event likelihoods are computed. They are based on different hypotheses regarding the scattering process at hand. Together they result in a function of the measured momenta which allows ...

  19. Single-channel EEG sleep stage classification based on a streamlined set of statistical features in wavelet domain.

    Science.gov (United States)

    da Silveira, Thiago L T; Kozakevicius, Alice J; Rodrigues, Cesar R

    2017-02-01

    The main objective of this study was to enhance the performance of sleep stage classification using single-channel electroencephalograms (EEGs), which are highly desirable for many emerging technologies, such as telemedicine and home care. The proposed method consists of decomposing EEGs by a discrete wavelet transform and computing the kurtosis, skewness and variance of its coefficients at selected levels. A random forest predictor is trained to classify each epoch into one of the Rechtschaffen and Kales' stages. By performing a comprehensive set of tests on 106,376 epochs available from the Physionet public database, it is demonstrated that the use of these three statistical moments has enhanced performance when compared to their application in the time domain. Furthermore, the chosen set of features has the advantage of exhibiting a stable classification performance for all scoring systems, i.e., from 2- to 6-state sleep stages. The stability of the feature set is confirmed with ReliefF tests which show a performance reduction when any individual feature is removed, suggesting that this group of feature cannot be further reduced. The accuracies and kappa coefficients yield higher than 90 % and 0.8, respectively, for all of the 2- to 6-state sleep stage classification cases.

  20. Sequential Total Variation Denoising for the Extraction of Fetal ECG from Single-Channel Maternal Abdominal ECG

    Directory of Open Access Journals (Sweden)

    Kwang Jin Lee

    2016-07-01

    Full Text Available Fetal heart rate (FHR is an important determinant of fetal health. Cardiotocography (CTG is widely used for measuring the FHR in the clinical field. However, fetal movement and blood flow through the maternal blood vessels can critically influence Doppler ultrasound signals. Moreover, CTG is not suitable for long-term monitoring. Therefore, researchers have been developing algorithms to estimate the FHR using electrocardiograms (ECGs from the abdomen of pregnant women. However, separating the weak fetal ECG signal from the abdominal ECG signal is a challenging problem. In this paper, we propose a method for estimating the FHR using sequential total variation denoising and compare its performance with that of other single-channel fetal ECG extraction methods via simulation using the Fetal ECG Synthetic Database (FECGSYNDB. Moreover, we used real data from PhysioNet fetal ECG databases for the evaluation of the algorithm performance. The R-peak detection rate is calculated to evaluate the performance of our algorithm. Our approach could not only separate the fetal ECG signals from the abdominal ECG signals but also accurately estimate the FHR.

  1. Sequential Total Variation Denoising for the Extraction of Fetal ECG from Single-Channel Maternal Abdominal ECG

    Science.gov (United States)

    Lee, Kwang Jin; Lee, Boreom

    2016-01-01

    Fetal heart rate (FHR) is an important determinant of fetal health. Cardiotocography (CTG) is widely used for measuring the FHR in the clinical field. However, fetal movement and blood flow through the maternal blood vessels can critically influence Doppler ultrasound signals. Moreover, CTG is not suitable for long-term monitoring. Therefore, researchers have been developing algorithms to estimate the FHR using electrocardiograms (ECGs) from the abdomen of pregnant women. However, separating the weak fetal ECG signal from the abdominal ECG signal is a challenging problem. In this paper, we propose a method for estimating the FHR using sequential total variation denoising and compare its performance with that of other single-channel fetal ECG extraction methods via simulation using the Fetal ECG Synthetic Database (FECGSYNDB). Moreover, we used real data from PhysioNet fetal ECG databases for the evaluation of the algorithm performance. The R-peak detection rate is calculated to evaluate the performance of our algorithm. Our approach could not only separate the fetal ECG signals from the abdominal ECG signals but also accurately estimate the FHR. PMID:27376296

  2. Influence of single-phase heat transfer correlations on safety analysis of research reactors with narrow rectangular fuel channels

    International Nuclear Information System (INIS)

    Rawashdeh, A.; Altamimi, R.; Lee, B.; Chung, Y. J.; Park, S.

    2013-01-01

    The influence of different single-phase heat transfer correlations on the fuel temperature and minimum critical heat flux ratio (MCHFR) during a typical accident of a 5 MW research reactor is investigated. A reactor uses plate type fuel, of which the cooling channels have a narrow rectangular shape. RELAP5/MOD3.3 tends to over-predict the Nusselt number (Nu) at a low Reynolds number (Re) region, and therefore the correlation set is modified to properly describe the thermal behavior at that region. To demonstrate the effect of Nu at a low-Re region on an accident analysis, a two-pump failure accident was chosen as a sample problem. In the accident, the downward core flow decreases by a pump coast-down, and then reverses upward by natural convection. During the pump coast-down and flow reversal, the flow undergoes a laminar flow regime which has a different Nu with respect to the correlation sets. Compared to the results by the original RELAP5/MOD3.3, the modified correlation set predicts the fuel temperature to be a little higher than the original value, and the MCHFR to be a little lower than the original value. Although the modified correlation set predicts the fuel temperature and the MCHFR to be less conservative than those calculated from the original correlation of RELAP5/MOD3.3, the maximum fuel temperature and the MCHFR still satisfy the safety acceptance criteria

  3. Measurement of the Top Quark Pair Production Cross-Section in the Single Lepton Channel with the ATLAS Experiment

    CERN Document Server

    Lange, C; The ATLAS collaboration

    2011-01-01

    The measurement of the top-quark pair production cross-section is a powerful tool to test the Standard Model (SM) at a new energy. With the recent advances in theoretical calculations that led to predictions at a precision level of 10%, this measurement particularly provides a precision test of the theory of Quantum Chromodynamics. At the same time, the decays of top-quark pairs are phenomenologically similar to processes predicted by beyond-SM theories, thus representing an irreducible background that has to be studied thoroughly. In this first phase of data taking of the ATLAS detector, a copious process like $t\\bar{t}$ production can be also exploited to test the performance of the detector itself. The single-lepton channel, in which the W boson produced in the decay of one top quark decays leptonically and the W boson from the other top quak decays hadronically, currently provides the best trade-off between experimental accessibility, production rate and background contamination. The measurement of the $t...

  4. The performance of the Hydromorphological Index of Diversity (HMID) in a hydropower affected meandering river

    Science.gov (United States)

    Stähly, Severin; Bourqui, Pierre; Franca, Mario J.; Robinson, Christopher; Schleiss, Anton J.

    2016-04-01

    More than half of the Swiss electricity is produced by hydropower. Large price fluctuations cause severe hydropeaking flow regimes due to corresponding production fluctuations, which undisputedly have a negative impact on aquatic biota. Water diversion due to dams on the other hand imposes downstream residual flow regimes. The absence of flood events and regular sediment supply disrupts sediment dynamics and disconnects floodplains, which are habitats of high value, from its main channel. The residual-flow controlled reach at the Sarine river in western Switzerland is the subject of the present study. The Sarine meanders strongly and the river reach under analysis has a bed incision of locally more than 100 m. Its incision provokes the isolation of the river which is consequently minimally touched by human structures and shows a natural geomorphology. Since the construction of a dam upstream this reach in 1948, aiming at the water abstraction to hydropower, vegetation could establish and the active floodplain decreased its area, as airborne images show. Nevertheless, it is classified as a floodplain of national importance and it has been under protection since 1992. It is supposed to be a valuable habitat for a wide range of organisms. The Hydromorphological Index of Diversity (HMID) is a simple tool for quantifying the habitat richness in a river reach, taking into account the mean values and the variation of water depth and flow velocity. For channelized rivers, HMID values from up to 5 are expected, while morphological pristine sites with a high spatial variability of water depth and velocity show values of 9 or higher. For the residual flow of the Sarine River, flow depth and velocity were measured using ADCP and ADV. The results are compared with a nearby natural reference river and the outcome of a 2D numerical simulation. Finally, the behaviour and limitations of the HMID, in a hydropower affected river, are discussed. In the close future an artificial flood

  5. Design of Meander Antenna for UHF Partial Discharge Detection of Transformers

    Directory of Open Access Journals (Sweden)

    Mengjie Li

    2014-05-01

    Full Text Available Ultra high frequency (UHF partial discharge (PD detection approaches take advantages of strong anti-interference ability, and have been considered as a promising technology for online monitoring PD signals. This paper presents a meander antenna with wide frequency band and small size for UHF PD detection in power transformers. The optimal geometric parameters of the meander antenna were obtained through the parametric investigation. A prototype of the proposed antenna was fabricated. Actual PD experiments were carried out for typical artificial insulation defect models while the antenna was used for PD measurements. The experimental results show that the proposed meander antenna is suitable and effective for UHF online monitoring of PDs in transformers.

  6. Offshore and onshore wind turbine wake meandering studied in an ABL wind tunnel

    DEFF Research Database (Denmark)

    Barlas, Emre; Buckingham, Sophia; Glabeke, Gertjan

    2015-01-01

    Scaled wind turbine models have been installed in the VKI L1-B atmospheric boundary layer wind tunnel at offshore and onshore conditions. Time-resolved measurements were carried out with three component hot wire anemometry and stereo-PIV in the middle vertical plane of the wake up to eleven turbine...... spectrum, present in the entire wake mainly for offshore inflow condition. It was found that the Strouhal number, based on the rotor diameter and the wind velocity at hub height, was in the order of 0.25. Below the meandering frequency, turbulence power spectrum decreased, whereas above it increased. Wake...... diameter downstream. The results show an earlier wake recovery for the onshore case. The effect of inflow conditions and the wind turbine’s working conditions on wake meandering was investigated. Wake meandering was detected by hot wire anemometry through a low frequency peak in the turbulent power...

  7. Measurement of t-Channel Single Top-Quark Production Cross-Section in pp Collisions at \\sqrt{s} = 8 TeV with the ATLAS detector

    CERN Document Server

    Tepel, P; The ATLAS collaboration

    2014-01-01

    This poster presents the measurement of a $t$-channel single top-quark production fiducial cross-section in the lepton+jets channel with 20.3 fb$^{-1}$ of 8 TeV data using a neural-network discriminant, based on ATLAS-CONF-2014-007. Events are selected by requiring exactly two jets, where one of the jets is required to be $b$-tagged. Signal events from $t$-channel single top-quark processes are enhanced using a neural-network discriminant based on final-state observables. The $t$-channel production cross-section in the fiducial region is obtained from a binned maximum-likelihood fit to the neural-network discriminant. A fiducial cross-section quoted within the detector acceptance of $\\sigma_{\\rm fid} = 3.37 \\pm 0.05 \\, (\\mathrm{stat.}) \\pm 0.47 \\, (\\mathrm{syst.}) \\pm 0.09 \\, (\\mathrm{lumi.})~\\text{pb}$ is obtained. The total inclusive $t$-channel cross-section is calculated using the acceptance predicted by various Monte Carlo generators. If the acceptance from the aMC@NLO + Herwig event generator is used, a...

  8. The effect of bedload transport rates on bedform and planform morphological development in a laboratory meandering stream under varying flow conditions

    Science.gov (United States)

    Sullivan, C.; Good, R. G. R.; Binns, A. D.

    2017-12-01

    Sediment transport processes in streams provides valuable insight into the temporal evolution of planform and bedform geometry. The majority of previous experimental research in the literature has focused on bedload transport and corresponding bedform development in rectangular, confined channels, which does not consider planform adjustment processes in streams. In contrast, research conducted with laboratory streams having movable banks can investigate planform development in addition to bedform development, which is more representative of natural streams. The goal of this research is to explore the relationship between bedload transport rates and the morphological adjustments in meandering streams. To accomplish this, a series of experimental runs were conducted in a 5.6 m by 1.9 m river basin flume at the University of Guelph to analyze the bedload impacts on bed formations and planform adjustments in response to varying flow conditions. In total, three experimental runs were conducted: two runs using steady state conditions and one run using unsteady flow conditions in the form of a symmetrical hydrograph implementing quasi steady state flow. The runs were performed in a series of time-steps in order to monitor the evolution of the stream morphology and the bedload transport rates. Structure from motion (SfM) was utilized to capture the channel morphology after each time-step, and Agisoft PhotoScan software was used to produce digital elevation models to analyze the morphological evolution of the channel with time. Bedload transport rates were quantified using a sediment catch at the end of the flume. Although total flow volumes were similar for each run, the morphological evolution and bedload transport rates in each run varied. The observed bedload transport rates from the flume are compared with existing bedload transport formulas to assess their accuracy with respect to sediment transport in unconfined meandering channels. The measured sediment transport

  9. Miniaturized bandpass filter using a meandered stepped-impedance resonator with a meandered-line stub-load on a GaAs substrate.

    Science.gov (United States)

    Chuluunbaatar, Z; Wang, C; Kim, N Y

    2014-01-01

    This paper reports a compact bandpass filter with improved skirt selectivity using integrated passive device fabrication technology on a GaAs substrate. The structure of the filter consists of electromagnetically coupled meandered-line symmetric stepped-impedance resonators. The strength of the coupling between the resonators is enhanced by using a meandered-line stub-load inside the resonators to improve the selectivity and miniaturize the size of the filter. In addition, the center frequency of the filter can be flexibly controlled by varying degrees of the capacitive coupling between resonator and stub-load. To verify the proposed concept, a protocol bandpass filter with center frequency of 6.53 GHz was designed, fabricated, and measured, with a return loss and insertion loss of 39.1 dB and 1.63 dB.

  10. Miniaturized Bandpass Filter Using a Meandered Stepped-Impedance Resonator with a Meandered-Line Stub-Load on a GaAs Substrate

    Directory of Open Access Journals (Sweden)

    Z. Chuluunbaatar

    2014-01-01

    Full Text Available This paper reports a compact bandpass filter with improved skirt selectivity using integrated passive device fabrication technology on a GaAs substrate. The structure of the filter consists of electromagnetically coupled meandered-line symmetric stepped-impedance resonators. The strength of the coupling between the resonators is enhanced by using a meandered-line stub-load inside the resonators to improve the selectivity and miniaturize the size of the filter. In addition, the center frequency of the filter can be flexibly controlled by varying degrees of the capacitive coupling between resonator and stub-load. To verify the proposed concept, a protocol bandpass filter with center frequency of 6.53 GHz was designed, fabricated, and measured, with a return loss and insertion loss of 39.1 dB and 1.63 dB.

  11. Search for the single top quarks produced in s-channel via electroweak interactions at √s = 1.96 at the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Jabeen, Shabnam [Univ. of Kansas, Lawrence, KS (United States)

    2006-01-01

    The authors present a search for single top quarks produced in the s-channel electroweak production mode. The search is performed in the electron+jets decay channels, with one or more secondary-vertex tagged jets to indicate the presence of a b-jet and hence improving the signal:background ratio. Separation between signal and background is further enhanced by the use of Feed Forward Neural networks. 360 pb-1 of Run II data used for this analysis was delivered by the Tevatron, and collected by D0 between August 2002 and August 2004. The resulting 95% confidence level upper limit is 4 pb.

  12. Fast adaptive OFDM-PON over single fiber loopback transmission using dynamic rate adaptation-based algorithm for channel performance improvement

    Science.gov (United States)

    Kartiwa, Iwa; Jung, Sang-Min; Hong, Moon-Ki; Han, Sang-Kook

    2014-03-01

    In this paper, we propose a novel fast adaptive approach that was applied to an OFDM-PON 20-km single fiber loopback transmission system to improve channel performance in term of stabilized BER below 2 × 10-3 and higher throughput beyond 10 Gb/s. The upstream transmission is performed through light source-seeded modulation using 1-GHz RSOA at the ONU. Experimental results indicated that the dynamic rate adaptation algorithm based on greedy Levin-Campello could be an effective solution to mitigate channel instability and data rate degradation caused by the Rayleigh back scattering effect and inefficient resource subcarrier allocation.

  13. EFFECT FOR A SINGLE ROUGHNESS E=5,63mm OF EXPERIMENTAL TO STUDY HYDRAULIC JUMP PROFILE IN A CHANNEL IN U A ROUGH BOTTOM

    Directory of Open Access Journals (Sweden)

    A. Ghomri

    2015-07-01

    Full Text Available This study aims to study the hydraulic jump controlled by threshold, moving in a channel profile 'U' bottomed rough for a single roughness E=5,63mm. Functional relations in dimensionless terms, linking the different characteristics of the projection, showing the effect of roughness of the bottom of the channel are obtained. The hydraulic jump is the primary means used by hydraulic structures to dissipate energy. This hydraulic jump is formed at the sharp transition from a supercritical flow a stream flow.

  14. EFFECT FOR A SINGLE ROUGHNESS E=5,63mm OF EXPERIMENTAL TO STUDY HYDRAULIC JUMP PROFILE IN A CHANNEL IN U A ROUGH BOTTOM

    Directory of Open Access Journals (Sweden)

    A. Ghomri

    2013-06-01

    Full Text Available This study aims to study the hydraulic jump controlled by threshold, moving in a channel profile 'U' bottomed rough for a single roughness E=5,63mm. Functional relations in dimensionless terms, linking the different characteristics of the projection, showing the effect of roughness of the bottom of the channel are obtained. The hydraulic jump is the primary means used by hydraulic structures to dissipate energy. This hydraulic jump is formed at the sharp transition from a supercritical flow a stream flow.

  15. Nitric oxide augments single Ca(2+) channel currents via cGMP-dependent protein kinase in Kenyon cells isolated from the mushroom body of the cricket brain.

    Science.gov (United States)

    Kosakai, Kumiko; Tsujiuchi, Yuuki; Yoshino, Masami

    2015-07-01

    Behavioral and pharmacological studies in insects have suggested that the nitric oxide (NO)/cyclic GMP (cGMP) signaling pathway is involved in the formation of long-term memory (LTM) associated with olfactory learning. However, the target molecules of NO and the downstream signaling pathway are still not known. In this study, we investigated the action of NO on single voltage-dependent Ca(2+) channels in the intrinsic neurons known as Kenyon cells within the mushroom body of the cricket brain, using the cell-attached configuration of the patch-clamp technique. Application of the NO donor S-nitrosoglutathione (GSNO) increased the open probability (NPO) of single Ca(2+) channel currents. This GSNO-induced increase was blocked by ODQ, a soluble guanylate cyclase (sGC) inhibitor, suggesting that the NO generated by GSNO acts via sGC to raise cGMP levels. The membrane-permeable cGMP analog 8-Bro-cGMP also increased the NPO of single Ca(2+) channel currents. Pretreatment of cells with KT5823, a protein kinase G blocker, abolished the excitatory effect of GSNO. These results suggest that NO augments the activity of single Ca(2+) channels via the cGMP/PKG signaling pathway. To gain insight into the physiological role of NO, we examined the effect of GSNO on action potentials of Kenyon cells under current-clamp conditions. Application of GSNO increased the frequency of action potentials elicited by depolarizing current injections, indicating that NO acts as a modulator resulting in a stimulatory signal in Kenyon cells. We discuss the increased Ca(2+) influx through these Ca(2+) channels via the NO/cGMP signaling cascade in relation to the formation of olfactory LTM. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Single-top production t-channel cross section measurement in the electron+jets final state at ATLAS with 35 pb-1of data

    International Nuclear Information System (INIS)

    Khoriauli, Gia

    2012-07-01

    The cross section of the Standard Model electroweak production of a single top quark in the t-channel has been measured using the LHC proton-proton collision data at √(s)=7 TeV, 35 pb -1 of integrated luminosity, recorded by the ATLAS detector during the year 2010. The measurement has been based on a selection of the collision events with an electron and one b-tagged hadronic jet in the central region of the detector and one extra jet in the forward region of the detector. These requirements are dictated by the topology of the final state particles in the t-channel process. They helped to optimize an expected fraction of the t-channel process, according to a study based on Monte-Carlo simulation, in the selected events and suppress the contribution of the background processes. The main background processes such as production of hadronic jets via the strong interaction and production of a single W boson with associated hadronic jets are measured by means of data driven methods developed in this work. The measured cross section of single top quark production in the t-channel process is 59 +44 -39 (stat.) +63 -39 (syst.) pb. The measured upper limit on the cross section is 226 pb at the 95% confidence level. The results are in agreement with the latest theoretical prediction of the t-channel cross section of the Standard Model production of a single top quark calculated at NNLO, 64.6 +3.3 -2.6 pb, considering m t-quark =172.5 GeV.

  17. Single-top production t-channel cross section measurement in the electron+jets final state at ATLAS with 35 pb{sup -1}of data

    Energy Technology Data Exchange (ETDEWEB)

    Khoriauli, Gia

    2012-07-15

    The cross section of the Standard Model electroweak production of a single top quark in the t-channel has been measured using the LHC proton-proton collision data at {radical}(s)=7 TeV, 35 pb{sup -1} of integrated luminosity, recorded by the ATLAS detector during the year 2010. The measurement has been based on a selection of the collision events with an electron and one b-tagged hadronic jet in the central region of the detector and one extra jet in the forward region of the detector. These requirements are dictated by the topology of the final state particles in the t-channel process. They helped to optimize an expected fraction of the t-channel process, according to a study based on Monte-Carlo simulation, in the selected events and suppress the contribution of the background processes. The main background processes such as production of hadronic jets via the strong interaction and production of a single W boson with associated hadronic jets are measured by means of data driven methods developed in this work. The measured cross section of single top quark production in the t-channel process is 59{sup +44}{sub -39}(stat.){sup +63}{sub -39}(syst.) pb. The measured upper limit on the cross section is 226 pb at the 95% confidence level. The results are in agreement with the latest theoretical prediction of the t-channel cross section of the Standard Model production of a single top quark calculated at NNLO, 64.6{sup +3.3}{sub -2.6} pb, considering m {sub t-quark}=172.5 GeV.

  18. Conversion of a DWDM signal to a single Nyquist channel based on a complete optical Fourier transformation

    DEFF Research Database (Denmark)

    Guan, Pengyu; Røge, Kasper Meldgaard; Mulvad, Hans Christian Hansen

    2014-01-01

    We propose a DWDM-to-Nyquist channel conversion scheme based on complete Optical Fourier Transformation and optical Nyquist filtering. We demonstrate conversion from 50-GHz-grid 16×10 Gbit/s DPSK DWDM to a 160-Gbit/s Nyquist channel (0.9 symbol/s/Hz spectral efficiency) with 1.4 dB power penalty....

  19. Efficacy of home single-channel nasal pressure for recommending continuous positive airway pressure treatment in sleep apnea.

    Science.gov (United States)

    Masa, Juan F; Duran-Cantolla, Joaquin; Capote, Francisco; Cabello, Marta; Abad, Jorge; Garcia-Rio, Francisco; Ferrer, Antoni; Fortuna, Ana M; Gonzalez-Mangado, Nicolas; de la Peña, Monica; Aizpuru, Felipe; Barbe, Ferran; Montserrat, Jose M

    2015-01-01

    Unlike other prevalent diseases, obstructive sleep apnea (OSA) has no simple tool for diagnosis and therapeutic decision-making in primary healthcare. Home single-channel nasal pressure (HNP) may be an alternative to polysomnography for diagnosis but its use in therapeutic decisions has yet to be explored. To ascertain whether an automatically scored HNP apnea-hypopnea index (AHI), used alone to recommend continuous positive airway pressure (CPAP) treatment, agrees with decisions made by a specialist using polysomnography and several clinical variables. Patients referred by primary care physicians for OSA suspicion underwent randomized polysomnography and HNP. We analyzed the total sample and both more and less symptomatic subgroups for Bland and Altman plots to explore AHI agreement; receiver operating characteristic curves to establish area under the curve (AUC) measurements for CPAP recommendation; and therapeutic decision efficacy for several HNP AHI cutoff points. Of the 787 randomized patients, 35 (4%) were lost, 378 (48%) formed the more symptomatic and 374 (48%) the less symptomatic subgroups. AHI bias and agreement limits were 5.8 ± 39.6 for the total sample, 5.3 ± 38.7 for the more symptomatic, and 6 ± 40.2 for the less symptomatic subgroups. The AUC were 0.826 for the total sample, 0.903 for the more symptomatic, and 0.772 for the less symptomatic subgroups. In the more symptomatic subgroup, 70% of patients could be correctly treated with CPAP. Automatic HNP scoring can correctly recommend CPAP treatment in most of more symptomatic patients with OSA suspicion. Our results suggest that this device may be an interesting tool in initial OSA management for primary care physicians, although future studies in a primary care setting are necessary. Clinicaltrial.gov identifier: NCT01347398. © 2014 Associated Professional Sleep Societies, LLC.

  20. Epileptic seizure classifications of single-channel scalp EEG data using wavelet-based features and SVM.

    Science.gov (United States)

    Janjarasjitt, Suparerk

    2017-10-01

    In this study, wavelet-based features of single-channel scalp EEGs recorded from subjects with intractable seizure are examined for epileptic seizure classification. The wavelet-based features extracted from scalp EEGs are simply based on detail and approximation coefficients obtained from the discrete wavelet transform. Support vector machine (SVM), one of the most commonly used classifiers, is applied to classify vectors of wavelet-based features of scalp EEGs into either seizure or non-seizure class. In patient-based epileptic seizure classification, a training data set used to train SVM classifiers is composed of wavelet-based features of scalp EEGs corresponding to the first epileptic seizure event. Overall, the excellent performance on patient-dependent epileptic seizure classification is obtained with the average accuracy, sensitivity, and specificity of, respectively, 0.9687, 0.7299, and 0.9813. The vector composed of two wavelet-based features of scalp EEGs provide the best performance on patient-dependent epileptic seizure classification in most cases, i.e., 19 cases out of 24. The wavelet-based features corresponding to the 32-64, 8-16, and 4-8 Hz subbands of scalp EEGs are the mostly used features providing the best performance on patient-dependent classification. Furthermore, the performance on both patient-dependent and patient-independent epileptic seizure classifications are also validated using tenfold cross-validation. From the patient-independent epileptic seizure classification validated using tenfold cross-validation, it is shown that the best classification performance is achieved using the wavelet-based features corresponding to the 64-128 and 4-8 Hz subbands of scalp EEGs.

  1. Extraction of fetal ECG signal by an improved method using extended Kalman smoother framework from single channel abdominal ECG signal.

    Science.gov (United States)

    Panigrahy, D; Sahu, P K

    2017-03-01

    This paper proposes a five-stage based methodology to extract the fetal electrocardiogram (FECG) from the single channel abdominal ECG using differential evolution (DE) algorithm, extended Kalman smoother (EKS) and adaptive neuro fuzzy inference system (ANFIS) framework. The heart rate of the fetus can easily be detected after estimation of the fetal ECG signal. The abdominal ECG signal contains fetal ECG signal, maternal ECG component, and noise. To estimate the fetal ECG signal from the abdominal ECG signal, removal of the noise and the maternal ECG component presented in it is necessary. The pre-processing stage is used to remove the noise from the abdominal ECG signal. The EKS framework is used to estimate the maternal ECG signal from the abdominal ECG signal. The optimized parameters of the maternal ECG components are required to develop the state and measurement equation of the EKS framework. These optimized maternal ECG parameters are selected by the differential evolution algorithm. The relationship between the maternal ECG signal and the available maternal ECG component in the abdominal ECG signal is nonlinear. To estimate the actual maternal ECG component present in the abdominal ECG signal and also to recognize this nonlinear relationship the ANFIS is used. Inputs to the ANFIS framework are the output of EKS and the pre-processed abdominal ECG signal. The fetal ECG signal is computed by subtracting the output of ANFIS from the pre-processed abdominal ECG signal. Non-invasive fetal ECG database and set A of 2013 physionet/computing in cardiology challenge database (PCDB) are used for validation of the proposed methodology. The proposed methodology shows a sensitivity of 94.21%, accuracy of 90.66%, and positive predictive value of 96.05% from the non-invasive fetal ECG database. The proposed methodology also shows a sensitivity of 91.47%, accuracy of 84.89%, and positive predictive value of 92.18% from the set A of PCDB.

  2. Three-dimensional single-channel thermal analysis of fully ceramic microencapsulated fuel via two-temperature homogenized model

    International Nuclear Information System (INIS)

    Lee, Yoonhee; Cho, Nam Zin

    2014-01-01

    Highlights: • Two-temperature homogenized model is applied to thermal analysis of fully ceramic microencapsulated (FCM) fuel. • Based on the results of Monte Carlo calculation, homogenized parameters are obtained. • 2-D FEM/1-D FDM hybrid method for the model is used to obtain 3-D temperature profiles. • The model provides the fuel-kernel and SiC matrix temperatures separately. • Compared to UO 2 fuel, the FCM fuel shows ∼560 K lower maximum temperatures at steady- and transient states. - Abstract: The fully ceramic microencapsulated (FCM) fuel, one of the accident tolerant fuel (ATF) concepts, consists of TRISO particles randomly dispersed in SiC matrix. This high heterogeneity in compositions leads to difficulty in explicit thermal calculation of such a fuel. For thermal analysis of a fuel element of very high temperature reactors (VHTRs) which has a similar configuration to FCM fuel, two-temperature homogenized model was recently proposed by the authors. The model was developed using particle transport Monte Carlo method for heat conduction problems. It gives more realistic temperature profiles, and provides the fuel-kernel and graphite temperatures separately. In this paper, we apply the two-temperature homogenized model to three-dimensional single-channel thermal analysis of the FCM fuel element for steady- and transient-states using 2-D FEM/1-D FDM hybrid method. In the analyses, we assume that the power distribution is uniform in radial direction at steady-state and that in axial direction it is in the form of cosine function for simplicity. As transient scenarios, we consider (i) coolant inlet temperature transient, (ii) inlet mass flow rate transient, and (iii) power transient. The results of analyses are compared to those of conventional UO 2 fuel having the same geometric dimension and operating conditions

  3. Extraction of contact resistance and channel parameters from the electrical characteristics of a single bottom-gate/top-contact organic transistor

    Science.gov (United States)

    Takagaki, Shunsuke; Yamada, Hirofumi; Noda, Kei

    2016-03-01

    A parameter extraction procedure for staggered-type organic field-effect transistors (OFETs), in which only the electrical characteristics of a single device are needed, was newly considered. The existing differential method and the transition voltage method for evaluating contact and channel parameters in OFETs were complementarily combined. The calibration of the total resistance between the source and the drain was also incorporated to compensate discrepancies in the total resistances calculated from output and transfer characteristics, caused by the existence of nonignorable contact resistance and carrier traps. By using our proposed method, gate-voltage-dependent contact resistance and channel mobility in the linear regime were evaluated for bottom-gate/top-contact pentacene thin-film transistors, and the channel-length dependence of these parameters was investigated. A series of results of parameter extraction confirm the validity of our proposed method, which is advantageous in avoiding the influences of characteristic variations that are frequently observed in practical OFET devices.

  4. Geomorphic changes resulting from floods in reconfigured gravel-bed river channels in Colorado, USA

    Science.gov (United States)

    Elliott, J.G.; Capesius, J.P.

    2009-01-01

    Geomorphic changes in reconfi gured reaches of three Colorado rivers in response to floods in 2005 provide a benchmark for "restoration" assessment. Sedimententrainment potential is expressed as the ratio of the shear stress from the 2 yr, 5 yr, 10 yr, and 2005 floods to the critical shear stress for sediment. Some observed response was explained by the excess of flood shear stress relative to the resisting force of the sediment. Bed-load entrainment in the Uncompahgre River and the North Fork Gunnison River, during 4 and 6 yr floods respectively, resulted in streambed scour, streambed deposition, lateral-bar accretion, and channel migration at various locations. Some constructed boulder and log structures failed because of high rates of bank erosion or bed-material deposition. The Lake Fork showed little or no net change after the 2005 flood; however, this channel had not conveyed floods greater than the 2.5 yr flood since reconfi guration. Channel slope and the 2 yr flood, a surrogate for bankfull discharge, from all three reconfi gured reaches plotted above the Leopold and Wolman channel-pattern threshold in the "braided channel" region, indicating that braiding, rather than a single-thread meandering channel, and midchannel bar formation may be the natural tendency of these gravel-bed reaches. When plotted against a total stream-power and median-sediment-size threshold for the 2 yr flood, however, the Lake Fork plotted in the "single-thread channel" region, the North Fork Gunnison plotted in the " multiplethread" region, and the Uncompahgre River plotted on the threshold. All three rivers plotted in the multiple-thread region for floods of 5 yr recurrence or greater. ?? 2009 Geological Society of America.

  5. Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation

    Directory of Open Access Journals (Sweden)

    Yool Andrea J

    2003-10-01

    Full Text Available Abstract Background Aquaporin-1 (AQP1 functions as an osmotic water channel and a gated cation channel. Activation of the AQP1 ion conductance by intracellular cGMP was hypothesized to involve the carboxyl (C- terminus, based on amino acid sequence alignments with cyclic-nucleotide-gated channels and cGMP-selective phosphodiesterases. Results Voltage clamp analyses of human AQP1 channels expressed in Xenopus oocytes demonstrated that the nitric oxide donor, sodium nitroprusside (SNP; 3–14 mM activated the ionic conductance response in a dose-dependent manner. Block of soluble guanylate cyclase prevented the response. Enzyme immunoassays confirmed a linear dose-dependent relationship between SNP and the resulting intracellular cGMP levels (up to 1700 fmol cGMP /oocyte at 14 mM SNP. Results here are the first to show that the efficacy of ion channel activation is decreased by mutations of AQP1 at conserved residues in the C-terminal domain (aspartate D237 and lysine K243. Conclusions These data support the idea that the limited amino acid sequence similarities found between three diverse classes of cGMP-binding proteins are significant to the function of AQP1 as a cGMP-gated ion channel, and provide direct evidence for the involvement of the AQP1 C-terminal domain in cGMP-mediated ion channel activation.

  6. Magnetoimpedance of thin film meander with composite coating layer containing Ni nanoparticles

    NARCIS (Netherlands)

    Lodewijk, K. J.; Fernandez, E.; Garcia-Arribas, A.; Kurlyandskaya, G. V.; Lepalovskij, V. N.; Safronov, A. P.; Kooi, B. J.

    2014-01-01

    Giant magnetoimpedance (GMI) [FeNi/Cu](4)/FeNi/Cu/[FeNi/Cu](4)/FeNi sensing meander elements were designed and tested aiming to develop a new instrumentation for characterization of polymer/magnetic nanoparticles composites. Acrylic copolymer of 95% of butyl methacrylate and 5% of methacrylic acid

  7. Bank retreat study of a meandering river reach case study : River Irwell

    NARCIS (Netherlands)

    Duran, R.; Beevers, L.; Crosato, A.; Wright, N.

    2010-01-01

    Lack of data is often considered a limitation when undertaking morphological studies. This research deals with morphological studies of small rivers experiencing bank erosion processes when only limited data are available. A reach of the meandering gravel-bed river Irwell (United Kingdom) is taken

  8. The Middle Sacramento River: Human Impacts on Physical and Ecological Processes Along a Meandering River

    Science.gov (United States)

    Koll Buer; Dave Forwalter; Mike Kissel; Bill Stohlert

    1989-01-01

    Native plant and wildlife communities along Northern California's middle Sacramento River (Red Bluff to Colusa) originally adapted to a changing pattern of erosion and deposition across a broad meander belt. The erosion-deposition process was in balance, with the river alternately building and eroding terraces. Human-induced changes to the Sacramento River,...

  9. A Novel Partial Discharge Ultra-High Frequency Signal De-Noising Method Based on a Single-Channel Blind Source Separation Algorithm

    Directory of Open Access Journals (Sweden)

    Liangliang Wei

    2018-02-01

    Full Text Available To effectively de-noise the Gaussian white noise and periodic narrow-band interference in the background noise of partial discharge ultra-high frequency (PD UHF signals in field tests, a novel de-noising method, based on a single-channel blind source separation algorithm, is proposed. Compared with traditional methods, the proposed method can effectively de-noise the noise interference, and the distortion of the de-noising PD signal is smaller. Firstly, the PD UHF signal is time-frequency analyzed by S-transform to obtain the number of source signals. Then, the single-channel detected PD signal is converted into multi-channel signals by singular value decomposition (SVD, and background noise is separated from multi-channel PD UHF signals by the joint approximate diagonalization of eigen-matrix method. At last, the source PD signal is estimated and recovered by the l1-norm minimization method. The proposed de-noising method was applied on the simulation test and field test detected signals, and the de-noising performance of the different methods was compared. The simulation and field test results demonstrate the effectiveness and correctness of the proposed method.

  10. Experimental study on the statistic characteristics of a 3x3 RF MIMO channel over a single conventional multimode fiber.

    Science.gov (United States)

    Lei, Yi; Li, Jianqiang; Wu, Rui; Fan, Yuting; Fu, Songnian; Yin, Feifei; Dai, Yitang; Xu, Kun

    2017-06-01

    Based on the observed random fluctuation phenomenon of speckle pattern across multimode fiber (MMF) facet and received optical power distribution across three output ports, we experimentally investigate the statistic characteristics of a 3×3 radio frequency multiple-input multiple-output (MIMO) channel enabled by mode division multiplexing in a conventional 50 µm MMF using non-mode-selective three-dimensional waveguide photonic lanterns as mode multiplexer and demultiplexer. The impacts of mode coupling on the MIMO channel coefficients, channel matrix, and channel capacity have been analyzed over different fiber lengths. The results indicate that spatial multiplexing benefits from the greater fiber length with stronger mode coupling, despite a higher optical loss.

  11. Observation of s -Channel Production of Single Top Quarks at the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Aaltonen, T.; Abazov, V. M.; Abbott, B.; Acharya, B. S.; Adams, M.; Adams, T.; Agnew, J. P.; Alexeev, G. D.; Alkhazov, G.; Alton, A.; Amerio, S.; Amidei, D.; Anastassov, A.; Annovi, A.; Antos, J.; Apollinari, G.; Appel, J. A.; Arisawa, T.; Artikov, A.; Asaadi, J.; Ashmanskas, W.; Askew, A.; Atkins, S.; Auerbach, B.; Augsten, K.; Aurisano, A.; Avila, C.; Azfar, F.; Badaud, F.; Badgett, W.; Bae, T.; Bagby, L.; Baldin, B.; Bandurin, D. V.; Banerjee, S.; Barbaro-Galtieri, A.; Barberis, E.; Baringer, P.; Barnes, V. E.; Barnett, B. A.; Barria, P.; Bartlett, J. F.; Bartos, P.; Bassler, U.; Bauce, M.; Bazterra, V.; Bean, A.; Bedeschi, F.; Begalli, M.; Behari, S.; Bellantoni, L.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Beretvas, A.; Beri, S. B.; Bernardi, G.; Bernhard, R.; Bertram, I.; Besançon, M.; Beuselinck, R.; Bhat, P. C.; Bhatia, S.; Bhatnagar, V.; Bhatti, A.; Bland, K. R.; Blazey, G.; Blessing, S.; Bloom, K.; Blumenfeld, B.; Bocci, A.; Bodek, A.; Boehnlein, A.; Boline, D.; Boos, E. E.; Borissov, G.; Bortoletto, D.; Borysova, M.; Boudreau, J.; Boveia, A.; Brandt, A.; Brandt, O.; Brigliadori, L.; Brock, R.; Bromberg, C.; Bross, A.; Brown, D.; Brucken, E.; Bu, X. B.; Budagov, J.; Budd, H. S.; Buehler, M.; Buescher, V.; Bunichev, V.; Burdin, S.; Burkett, K.; Busetto, G.; Bussey, P.; Buszello, C. P.; Butti, P.; Buzatu, A.; Calamba, A.; Camacho-Pérez, E.; Camarda, S.; Campanelli, M.; Canelli, F.; Carls, B.; Carlsmith, D.; Carosi, R.; Carrillo, S.; Casal, B.; Casarsa, M.; Casey, B. C. K.; Castilla-Valdez, H.; Castro, A.; Catastini, P.; Caughron, S.; Cauz, D.; Cavaliere, V.; Cavalli-Sforza, M.; Cerri, A.; Cerrito, L.; Chakrabarti, S.; Chan, K. M.; Chandra, A.; Chapon, E.; Chen, G.; Chen, Y. C.; Chertok, M.; Chiarelli, G.; Chlachidze, G.; Cho, K.; Cho, S. W.; Choi, S.; Chokheli, D.; Choudhary, B.; Cihangir, S.; Claes, D.; Clark, A.; Clarke, C.; Clutter, J.; Convery, M. E.; Conway, J.; Cooke, M.; Cooper, W. E.; Corbo, M.; Corcoran, M.; Cordelli, M.; Couderc, F.; Cousinou, M. -C.; Cox, C. A.; Cox, D. J.; Cremonesi, M.; Cruz, D.; Cuevas, J.; Culbertson, R.; Cutts, D.; Das, A.; d’Ascenzo, N.; Datta, M.; Davies, G.; de Barbaro, P.; de Jong, S. J.; De La Cruz-Burelo, E.; Déliot, F.; Demina, R.; Demortier, L.; Deninno, M.; Denisov, D.; Denisov, S. P.; D’Errico, M.; Desai, S.; Deterre, C.; DeVaughan, K.; Devoto, F.; Di Canto, A.; Di Ruzza, B.; Diehl, H. T.; Diesburg, M.; Ding, P. F.; Dittmann, J. R.; Dominguez, A.; Donati, S.; D’Onofrio, M.; Dorigo, M.; Driutti, A.; Dubey, A.; Dudko, L. V.; Duperrin, A.; Dutt, S.; Eads, M.; Ebina, K.; Edgar, R.; Edmunds, D.; Elagin, A.; Ellison, J.; Elvira, V. D.; Enari, Y.; Erbacher, R.; Errede, S.; Esham, B.; Evans, H.; Evdokimov, V. N.; Farrington, S.; Feng, L.; Ferbel, T.; Fernández Ramos, J. P.; Fiedler, F.; Field, R.; Filthaut, F.; Fisher, W.; Fisk, H. E.; Flanagan, G.; Forrest, R.; Fortner, M.; Fox, H.; Franklin, M.; Freeman, J. C.; Frisch, H.; Fuess, S.; Funakoshi, Y.; Galloni, C.; Garbincius, P. H.; Garcia-Bellido, A.; García-González, J. A.; Garfinkel, A. F.; Garosi, P.; Gavrilov, V.; Geng, W.; Gerber, C. E.; Gerberich, H.; Gerchtein, E.; Gershtein, Y.; Giagu, S.; Giakoumopoulou, V.; Gibson, K.; Ginsburg, C. M.; Ginther, G.; Giokaris, N.; Giromini, P.; Giurgiu, G.; Glagolev, V.; Glenzinski, D.; Gold, M.; Goldin, D.; Golossanov, A.; Golovanov, G.; Gomez, G.; Gomez-Ceballos, G.; Goncharov, M.; González López, O.; Gorelov, I.; Goshaw, A. T.; Goulianos, K.; Gramellini, E.; Grannis, P. D.; Greder, S.; Greenlee, H.; Grenier, G.; Grinstein, S.; Gris, Ph.; Grivaz, J. -F.; Grohsjean, A.; Grosso-Pilcher, C.; Group, R. C.; Grünendahl, S.; Grünewald, M. W.; Guillemin, T.; Guimaraes da Costa, J.; Gutierrez, G.; Gutierrez, P.; Hahn, S. R.; Haley, J.; Han, J. Y.; Han, L.; Happacher, F.; Hara, K.; Harder, K.; Hare, M.; Harel, A.; Harr, R. F.; Harrington-Taber, T.; Hatakeyama, K.; Hauptman, J. M.; Hays, C.; Hays, J.; Head, T.; Hebbeker, T.; Hedin, D.; Hegab, H.; Heinrich, J.; Heinson, A. P.; Heintz, U.; Hensel, C.; Heredia-De La Cruz, I.; Herndon, M.; Herner, K.; Hesketh, G.; Hildreth, M. D.; Hirosky, R.; Hoang, T.; Hobbs, J. D.; Hocker, A.; Hoeneisen, B.; Hogan, J.; Hohlfeld, M.; Holzbauer, J. L.; Hong, Z.; Hopkins, W.; Hou, S.; Howley, I.; Hubacek, Z.; Hughes, R. E.; Husemann, U.; Hussein, M.; Huston, J.; Hynek, V.; Iashvili, I.; Ilchenko, Y.; Illingworth, R.; Introzzi, G.; Iori, M.; Ito, A. S.; Ivanov, A.; Jabeen, S.; Jaffré, M.; James, E.; Jang, D.; Jayasinghe, A.; Jayatilaka, B.; Jeon, E. J.; Jeong, M. S.; Jesik, R.; Jiang, P.; Jindariani, S.; Johns, K.; Johnson, E.; Johnson, M.; Jonckheere, A.; Jones, M.; Jonsson, P.; Joo, K. K.; Joshi, J.; Jun, S. Y.; Jung, A. W.; Junk, T. R.; Juste, A.; Kajfasz, E.; Kambeitz, M.; Kamon, T.; Karchin, P. E.; Karmanov, D.; Kasmi, A.; Kato, Y.; Katsanos, I.; Kehoe, R.; Kermiche, S.; Ketchum, W.; Keung, J.; Khalatyan, N.; Khanov, A.; Kharchilava, A.; Kharzheev, Y. N.; Kilminster, B.; Kim, D. H.; Kim, H. S.; Kim, J. E.; Kim, M. J.; Kim, S. H.; Kim, S. B.; Kim, Y. J.; Kim, Y. K.; Kimura, N.; Kirby, M.; Kiselevich, I.; Knoepfel, K.; Kohli, J. M.; Kondo, K.; Kong, D. J.; Konigsberg, J.; Kotwal, A. V.; Kozelov, A. V.; Kraus, J.; Kreps, M.; Kroll, J.; Kruse, M.; Kuhr, T.; Kumar, A.; Kupco, A.; Kurata, M.; Kurča, T.; Kuzmin, V. A.; Laasanen, A. T.; Lammel, S.; Lammers, S.; Lancaster, M.; Lannon, K.; Latino, G.; Lebrun, P.; Lee, H. S.; Lee, H. S.; Lee, J. S.; Lee, S. W.; Lee, W. M.; Lei, X.; Lellouch, J.; Leo, S.; Leone, S.; Lewis, J. D.; Li, D.; Li, H.; Li, L.; Li, Q. Z.; Lim, J. K.; Limosani, A.; Lincoln, D.; Linnemann, J.; Lipaev, V. V.; Lipeles, E.; Lipton, R.; Lister, A.; Liu, H.; Liu, H.; Liu, Q.; Liu, T.; Liu, Y.; Lobodenko, A.; Lockwitz, S.; Loginov, A.; Lokajicek, M.; Lopes de Sa, R.; Lucchesi, D.; Lucà, A.; Lueck, J.; Lujan, P.; Lukens, P.; Luna-Garcia, R.; Lungu, G.; Lyon, A. L.; Lys, J.; Lysak, R.; Maciel, A. K. A.; Madar, R.; Madrak, R.; Maestro, P.; Magaña-Villalba, R.; Malik, S.; Malik, S.; Malyshev, V. L.; Manca, G.; Manousakis-Katsikakis, A.; Mansour, J.; Marchese, L.; Margaroli, F.; Marino, P.; Martínez-Ortega, J.; Martínez, M.; Matera, K.; Mattson, M. E.; Mazzacane, A.; Mazzanti, P.; McCarthy, R.; McGivern, C. L.; McNulty, R.; Mehta, A.; Mehtala, P.; Meijer, M. M.; Melnitchouk, A.; Menezes, D.; Mercadante, P. G.; Merkin, M.; Mesropian, C.; Meyer, A.; Meyer, J.; Miao, T.; Miconi, F.; Mietlicki, D.; Mitra, A.; Miyake, H.; Moed, S.; Moggi, N.; Mondal, N. K.; Moon, C. S.; Moore, R.; Morello, M. J.; Mukherjee, A.; Mulhearn, M.; Muller, Th.; Murat, P.; Mussini, M.; Nachtman, J.; Nagai, Y.; Naganoma, J.; Nagy, E.; Nakano, I.; Napier, A.; Narain, M.; Nayyar, R.; Neal, H. A.; Negret, J. P.; Nett, J.; Neu, C.; Neustroev, P.; Nguyen, H. T.; Nigmanov, T.; Nodulman, L.; Noh, S. Y.; Norniella, O.; Nunnemann, T.; Oakes, L.; Oh, S. H.; Oh, Y. D.; Oksuzian, I.; Okusawa, T.; Orava, R.; Orduna, J.; Ortolan, L.; Osman, N.; Osta, J.; Pagliarone, C.; Pal, A.; Palencia, E.; Palni, P.; Papadimitriou, V.; Parashar, N.; Parihar, V.; Park, S. K.; Parker, W.; Partridge, R.; Parua, N.; Patwa, A.; Pauletta, G.; Paulini, M.; Paus, C.; Penning, B.; Perfilov, M.; Peters, Y.; Petridis, K.; Petrillo, G.; Pétroff, P.; Phillips, T. J.; Piacentino, G.; Pianori, E.; Pilot, J.; Pitts, K.; Plager, C.; Pleier, M. -A.; Podstavkov, V. M.; Pondrom, L.; Popov, A. V.; Poprocki, S.; Potamianos, K.; Pranko, A.; Prewitt, M.; Price, D.; Prokopenko, N.; Prokoshin, F.; Ptohos, F.; Punzi, G.; Qian, J.; Quadt, A.; Quinn, B.; Ranjan, N.; Ratoff, P. N.; Razumov, I.; Redondo Fernández, I.; Renton, P.; Rescigno, M.; Rimondi, F.; Ripp-Baudot, I.; Ristori, L.; Rizatdinova, F.; Robson, A.; Rodriguez, T.; Rolli, S.; Rominsky, M.; Ronzani, M.; Roser, R.; Rosner, J. L.; Ross, A.; Royon, C.; Rubinov, P.; Ruchti, R.; Ruffini, F.; Ruiz, A.; Russ, J.; Rusu, V.; Sajot, G.; Sakumoto, W. K.; Sakurai, Y.; Sánchez-Hernández, A.; Sanders, M. P.; Santi, L.; Santos, A. S.; Sato, K.; Savage, G.; Saveliev, V.; Savoy-Navarro, A.; Sawyer, L.; Scanlon, T.; Schamberger, R. D.; Scheglov, Y.; Schellman, H.; Schlabach, P.; Schmidt, E. E.; Schwanenberger, C.; Schwarz, T.; Schwienhorst, R.; Scodellaro, L.; Scuri, F.; Seidel, S.; Seiya, Y.; Sekaric, J.; Semenov, A.; Severini, H.; Sforza, F.; Shabalina, E.; Shalhout, S. Z.; Shary, V.; Shaw, S.; Shchukin, A. A.; Shears, T.; Shepard, P. F.; Shimojima, M.; Shochet, M.; Shreyber-Tecker, I.; Simak, V.; Simonenko, A.; Skubic, P.; Slattery, P.; Sliwa, K.; Smirnov, D.; Smith, J. R.; Snider, F. D.; Snow, G. R.; Snow, J.; Snyder, S.; Söldner-Rembold, S.; Song, H.; Sonnenschein, L.; Sorin, V.; Soustruznik, K.; St. Denis, R.; Stancari, M.; Stark, J.; Stentz, D.; Stoyanova, D. A.; Strauss, M.; Strologas, J.; Sudo, Y.; Sukhanov, A.; Suslov, I.; Suter, L.; Svoisky, P.; Takemasa, K.; Takeuchi, Y.; Tang, J.; Tecchio, M.; Teng, P. K.; Thom, J.; Thomson, E.; Thukral, V.; Titov, M.; Toback, D.; Tokar, S.; Tokmenin, V. V.; Tollefson, K.; Tomura, T.; Tonelli, D.; Torre, S.; Torretta, D.; Totaro, P.; Trovato, M.; Tsai, Y. -T.; Tsybychev, D.; Tuchming, B.; Tully, C.; Ukegawa, F.; Uozumi, S.; Uvarov, L.; Uvarov, S.; Uzunyan, S.; Van Kooten, R.; van Leeuwen, W. M.; Varelas, N.; Varnes, E. W.; Vasilyev, I. A.; Vázquez, F.; Velev, G.; Vellidis, C.; Verkheev, A. Y.; Vernieri, C.; Vertogradov, L. S.; Verzocchi, M.; Vesterinen, M.; Vidal, M.; Vilanova, D.; Vilar, R.; Vizán, J.; Vogel, M.; Vokac, P.; Volpi, G.; Wagner, P.; Wahl, H. D.; Wallny, R.; Wang, M. H. L. S.; Wang, S. M.; Warchol, J.; Waters, D.; Watts, G.; Wayne, M.; Weichert, J.; Welty-Rieger, L.; Wester, W. C.; Whiteson, D.; Wicklund, A. B.; Wilbur, S.; Williams, H. H.; Williams, M. R. J.; Wilson, G. W.; Wilson, J. S.; Wilson, P.; Winer, B. L.; Wittich, P.; Wobisch, M.; Wolbers, S.; Wolfe, H.; Wood, D. R.; Wright, T.; Wu, X.; Wu, Z.; Wyatt, T. R.; Xie, Y.; Yamada, R.; Yamamoto, K.; Yamato, D.; Yang, S.; Yang, T.; Yang, U. K.; Yang, Y. C.; Yao, W. -M.; Yasuda, T.; Yatsunenko, Y. A.; Ye, W.; Ye, Z.; Yeh, G. P.; Yi, K.; Yin, H.; Yip, K.; Yoh, J.; Yorita, K.; Yoshida, T.; Youn, S. W.; Yu, G. B.; Yu, I.; Yu, J. M.; Zanetti, A. M.; Zeng, Y.; Zennamo, J.; Zhao, T. G.; Zhou, B.; Zhou, C.; Zhu, J.; Zielinski, M.; Zieminska, D.; Zivkovic, L.; Zucchelli, S.

    2014-06-01

    We report the first observation of single-top-quark production in the s channel through the combination of the CDF and D0 measurements of the cross section in proton-antiproton collisions at a center-of-mass energy of 1.96 TeV. The data correspond to total integrated luminosities of up to 9.7 fb-1 per experiment. The measured cross section is $\\sigma_s = 1.29^{+0.26}_{-0.24}$ pb. The probability of observing a statistical fluctuation of the background to a cross section of the observed size or larger is $1.8 \\times 10^{-10}$, corresponding to a significance of 6.3 standard deviations for the presence of an s-channel contribution to the production of single-top quarks.

  12. Measuring Single-Bond Rupture Forces Using High Electric Fields in Microfluidic Channels and DNA Oligomers as Force Tags

    OpenAIRE

    Breisch, Stefanie; Gonska, Julian; Deissler, Helmut; Stelzle, Martin

    2005-01-01

    The disruption force of specific biotin-streptavidin bonds was determined using DNA oligomers as force tags. Forces were generated by an electric field acting on a biotinylated fluorescently labeled DNA oligomer. DNA oligomers were immobilized via biotin-streptavidin bonds on the walls of microfluidic channels. Channel layout and fluid-based deposition process were designed to enable well-defined localized deposition of the oligomers in a narrow gap of the microchannel. Electric fields of up ...

  13. Chimeras Reveal a Single Lipid-Interface Residue that Controls MscL Channel Kinetics as well as Mechanosensitivity

    Directory of Open Access Journals (Sweden)

    Li-Min Yang

    2013-02-01

    Full Text Available MscL, the highly conserved bacterial mechanosensitive channel of large conductance, serves as an osmotic “emergency release valve,” is among the best-studied mechanosensors, and is a paradigm of how a channel senses and responds to membrane tension. Although all homologs tested thus far encode channel activity, many show functional differences. We tested Escherichia coli and Staphylococcus aureus chimeras and found that the periplasmic region of the protein, particularly E. coli I49 and the equivalent S. aureus F47 at the periplasmic lipid-aqueous interface of the first transmembrane domain, drastically influences both the open dwell time and the threshold of channel opening. One mutant shows a severe hysteresis, confirming the importance of this residue in determining the energy barriers for channel gating. We propose that this site acts similarly to a spring for a clasp knife, adjusting the resistance for obtaining and stabilizing an open or closed channel structure.

  14. Evidence for s-channel single top quark production in ppˉ collisions at √s = 1.96 TeV

    Czech Academy of Sciences Publication Activity Database

    Abazov, V. M.; Abbott, B.; Acharya, B.S.; Kupčo, Alexander; Lokajíček, Miloš

    2013-01-01

    Roč. 726, 4-5 (2013), s. 656-664 ISSN 0370-2693 R&D Projects: GA MŠk(CZ) LG12006 Institutional support: RVO:68378271 Keywords : D0 * channel cross section * measured * top * single production * Batavia TEVATRON Coll * CKM matrix * anti-p p * interaction * bottom * associated production Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 6.019, year: 2013 http://www.sciencedirect.com/science/article/pii/S037026931300779X

  15. Measurement of the $s$-channel Single Top Quark Cross Section at the CDF Experiment and Contributions to the Evidence of $H\\rightarrow bb$ at the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hao [Univ. of Virginia, Charlottesville, VA (United States)

    2014-08-01

    In this thesis, we present the measurement of the s-channel single top quark production cross section. In the cross section measurement we use data generated by protonantiproton collisions at the center-of-mass energy √s = 1.96 TeV and collected by the CDF Run II detector. The total data set corresponds to an integrated luminosity of 9.4 fb-1.

  16. An automatic algorithm for blink-artifact suppression based on iterative template matching: application to single channel recording of cortical auditory evoked potentials

    Science.gov (United States)

    Valderrama, Joaquin T.; de la Torre, Angel; Van Dun, Bram

    2018-02-01

    Objective. Artifact reduction in electroencephalogram (EEG) signals is usually necessary to carry out data analysis appropriately. Despite the large amount of denoising techniques available with a multichannel setup, there is a lack of efficient algorithms that remove (not only detect) blink-artifacts from a single channel EEG, which is of interest in many clinical and research applications. This paper describes and evaluates the iterative template matching and suppression (ITMS), a new method proposed for detecting and suppressing the artifact associated with the blink activity from a single channel EEG. Approach. The approach of ITMS consists of (a) an iterative process in which blink-events are detected and the blink-artifact waveform of the analyzed subject is estimated, (b) generation of a signal modeling the blink-artifact, and (c) suppression of this signal from the raw EEG. The performance of ITMS is compared with the multi-window summation of derivatives within a window (MSDW) technique using both synthesized and real EEG data. Main results. Results suggest that ITMS presents an adequate performance in detecting and suppressing blink-artifacts from a single channel EEG. When applied to the analysis of cortical auditory evoked potentials (CAEPs), ITMS provides a significant quality improvement in the resulting responses, i.e. in a cohort of 30 adults, the mean correlation coefficient improved from 0.37 to 0.65 when the blink-artifacts were detected and suppressed by ITMS. Significance. ITMS is an efficient solution to the problem of denoising blink-artifacts in single-channel EEG applications, both in clinical and research fields. The proposed ITMS algorithm is stable; automatic, since it does not require human intervention; low-invasive, because the EEG segments not contaminated by blink-artifacts remain unaltered; and easy to implement, as can be observed in the Matlab script implemeting the algorithm provided as supporting material.

  17. Determination of real-time predictors of the wind turbine wake meandering

    Science.gov (United States)

    Muller, Yann-Aël; Aubrun, Sandrine; Masson, Christian

    2015-03-01

    The present work proposes an experimental methodology to characterize the unsteady properties of a wind turbine wake, called meandering, and particularly its ability to follow the large-scale motions induced by large turbulent eddies contained in the approach flow. The measurements were made in an atmospheric boundary layer wind tunnel. The wind turbine model is based on the actuator disc concept. One part of the work has been dedicated to the development of a methodology for horizontal wake tracking by mean of a transverse hot wire rake, whose dynamic response is adequate for spectral analysis. Spectral coherence analysis shows that the horizontal position of the wake correlates well with the upstream transverse velocity, especially for wavelength larger than three times the diameter of the disc but less so for smaller scales. Therefore, it is concluded that the wake is actually a rather passive tracer of the large surrounding turbulent structures. The influence of the rotor size and downstream distance on the wake meandering is studied. The fluctuations of the lateral force and the yawing torque affecting the wind turbine model are also measured and correlated with the wake meandering. Two approach flow configurations are then tested: an undisturbed incoming flow (modelled atmospheric boundary layer) and a disturbed incoming flow, with a wind turbine model located upstream. Results showed that the meandering process is amplified by the presence of the upstream wake. It is shown that the coherence between the lateral force fluctuations and the horizontal wake position is significant up to length scales larger than twice the wind turbine model diameter. This leads to the conclusion that the lateral force is a better candidate than the upstream transverse velocity to predict in real time the meandering process, for either undisturbed (wake free) or disturbed incoming atmospheric flows.

  18. Search for s-channel single top-quark production in proton–proton collisions at s=8 TeV with the ATLAS detector

    Directory of Open Access Journals (Sweden)

    G. Aad

    2015-01-01

    Full Text Available This Letter presents a search at the LHC for s-channel single top-quark production in proton–proton collisions at a centre-of-mass energy of 8 TeV. The analyzed data set was recorded by the ATLAS detector and corresponds to an integrated luminosity of 20.3 fb−1. Selected events contain one charged lepton, large missing transverse momentum and exactly two b-tagged jets. A multivariate event classifier based on boosted decision trees is developed to discriminate s-channel single top-quark events from the main background contributions. The signal extraction is based on a binned maximum-likelihood fit of the output classifier distribution. The analysis leads to an upper limit on the s-channel single top-quark production cross-section of 14.6 pb at the 95% confidence level. The fit gives a cross-section of σs=5.0±4.3 pb, consistent with the Standard Model expectation.

  19. Search for s-channel single top-quark production in proton-proton collisions at $\\sqrt{s}$=8 TeV with the ATLAS detector

    CERN Document Server

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Astalos, Robert; Atkinson, Markus; Atlay, Naim Bora; Auerbach, Benjamin; Augsten, Kamil; Aurousseau, Mathieu; Avolio, Giuseppe; Axen, Bradley; Azuelos, Georges; Azuma, Yuya; Baak, Max; Baas, Alessandra; Bacci, Cesare; Bachacou, Henri; Bachas, Konstantinos; Backes, Moritz; Backhaus, Malte; Backus Mayes, John; Badescu, Elisabeta; Bagiacchi, Paolo; Bagnaia, Paolo; Bai, Yu; Bain, Travis; Baines, John; Baker, Oliver Keith; Balek, Petr; Balli, Fabrice; Banas, Elzbieta; Banerjee, Swagato; Bannoura, Arwa A E; Bansal, Vikas; Bansil, Hardeep Singh; Barak, Liron; Baranov, Sergei; Barberio, Elisabetta Luigia; Barberis, Dario; Barbero, Marlon; Barillari, Teresa; Barisonzi, Marcello; Barklow, Timothy; Barlow, Nick; Barnes, Sarah Louise; Barnett, Bruce; Barnett, Michael; Barnovska, Zuzana; Baroncelli, Antonio; Barone, Gaetano; Barr, Alan; Barreiro, Fernando; Barreiro Guimarães da Costa, João; Bartoldus, Rainer; Barton, Adam Edward; Bartos, Pavol; Bartsch, Valeria; Bassalat, Ahmed; Basye, Austin; Bates, Richard; 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Cuthbert, Cameron; Czirr, Hendrik; Czodrowski, Patrick; D'Auria, Saverio; D'Onofrio, Monica; Da Cunha Sargedas De Sousa, Mario Jose; Da Via, Cinzia; Dabrowski, Wladyslaw; Dafinca, Alexandru; Dai, Tiesheng; Dale, Orjan; Dallaire, Frederick; Dallapiccola, Carlo; Dam, Mogens; Daniells, Andrew Christopher; Dano Hoffmann, Maria; Dao, Valerio; Darbo, Giovanni; Darmora, Smita; Dassoulas, James; Dattagupta, Aparajita; Davey, Will; David, Claire; Davidek, Tomas; Davies, Eleanor; Davies, Merlin; Davignon, Olivier; Davison, Adam; Davison, Peter; Davygora, Yuriy; Dawe, Edmund; Dawson, Ian; Daya-Ishmukhametova, Rozmin; De, Kaushik; de Asmundis, Riccardo; De Castro, Stefano; De Cecco, Sandro; De Groot, Nicolo; de Jong, Paul; De la Torre, Hector; De Lorenzi, Francesco; De Nooij, Lucie; De Pedis, Daniele; De Salvo, Alessandro; De Sanctis, Umberto; De Santo, Antonella; De Vivie De Regie, Jean-Baptiste; Dearnaley, William James; Debbe, Ramiro; Debenedetti, Chiara; Dechenaux, Benjamin; Dedovich, Dmitri; Deigaard, Ingrid; Del Peso, Jose; Del Prete, Tarcisio; Deliot, Frederic; Delitzsch, Chris Malena; Deliyergiyev, Maksym; Dell'Acqua, Andrea; Dell'Asta, Lidia; Dell'Orso, Mauro; Della Pietra, Massimo; della Volpe, Domenico; Delmastro, Marco; Delsart, Pierre-Antoine; Deluca, Carolina; DeMarco, David; Demers, Sarah; Demichev, Mikhail; Demilly, Aurelien; Denisov, Sergey; Derendarz, Dominik; Derkaoui, Jamal Eddine; Derue, Frederic; Dervan, Paul; Desch, Klaus Kurt; Deterre, Cecile; Deviveiros, Pier-Olivier; Dewhurst, Alastair; Dhaliwal, Saminder; Di Ciaccio, Anna; Di Ciaccio, Lucia; Di Domenico, Antonio; Di Donato, Camilla; Di Girolamo, Alessandro; Di Girolamo, Beniamino; Di Mattia, Alessandro; Di Micco, Biagio; Di Nardo, Roberto; Di Simone, Andrea; Di Sipio, Riccardo; Di Valentino, David; Dias, Flavia; Diaz, Marco Aurelio; Diehl, Edward; Dietrich, Janet; Dietzsch, Thorsten; Diglio, Sara; Dimitrievska, Aleksandra; Dingfelder, Jochen; Dita, Petre; Dita, Sanda; Dittus, Fridolin; Djama, Fares; Djobava, Tamar; Djuvsland, Julia Isabell; Barros do Vale, Maria Aline; Dobos, Daniel; Doglioni, Caterina; Doherty, Tom; Dohmae, Takeshi; Dolejsi, Jiri; Dolezal, Zdenek; Dolgoshein, Boris; Donadelli, Marisilvia; Donati, Simone; Dondero, Paolo; Donini, Julien; Dopke, Jens; Doria, Alessandra; Dova, Maria-Teresa; Doyle, Tony; Dris, Manolis; Dubbert, Jörg; Dube, Sourabh; Dubreuil, Emmanuelle; Duchovni, Ehud; Duckeck, Guenter; Ducu, Otilia Anamaria; Duda, Dominik; Dudarev, Alexey; Dudziak, Fanny; Duflot, Laurent; Duguid, Liam; Dührssen, Michael; Dunford, Monica; Duran Yildiz, Hatice; Düren, Michael; Durglishvili, Archil; Dwuznik, Michal; Dyndal, Mateusz; Ebke, Johannes; Edson, William; Edwards, Nicholas Charles; Ehrenfeld, Wolfgang; Eifert, Till; Eigen, Gerald; Einsweiler, Kevin; Ekelof, Tord; El Kacimi, Mohamed; Ellert, Mattias; Elles, Sabine; Ellinghaus, Frank; Ellis, Nicolas; Elmsheuser, Johannes; Elsing, Markus; Emeliyanov, Dmitry; Enari, Yuji; Endner, Oliver Chris; Endo, Masaki; Engelmann, Roderich; Erdmann, Johannes; Ereditato, Antonio; Eriksson, Daniel; Ernis, Gunar; Ernst, Jesse; Ernst, Michael; Ernwein, Jean; Errede, Deborah; Errede, Steven; Ertel, Eugen; Escalier, Marc; Esch, Hendrik; Escobar, Carlos; Esposito, Bellisario; Etienvre, Anne-Isabelle; Etzion, Erez; Evans, Hal; Ezhilov, Alexey; Fabbri, Laura; Facini, Gabriel; Fakhrutdinov, Rinat; Falciano, Speranza; Falla, Rebecca Jane; Faltova, Jana; Fang, Yaquan; Fanti, Marcello; Farbin, Amir; Farilla, Addolorata; Farooque, Trisha; Farrell, Steven; Farrington, Sinead; Farthouat, Philippe; Fassi, Farida; Fassnacht, Patrick; Fassouliotis, Dimitrios; Favareto, Andrea; Fayard, Louis; Federic, Pavol; Fedin, Oleg; Fedorko, Wojciech; Fehling-Kaschek, Mirjam; Feigl, Simon; Feligioni, Lorenzo; Feng, Cunfeng; Feng, Eric; Feng, Haolu; Fenyuk, Alexander; Fernandez Perez, Sonia; Ferrag, Samir; Ferrando, James; Ferrari, Arnaud; Ferrari, Pamela; Ferrari, Roberto; Ferreira de Lima, Danilo Enoque; Ferrer, Antonio; Ferrere, Didier; Ferretti, Claudio; Ferretto Parodi, Andrea; Fiascaris, Maria; Fiedler, Frank; Filipčič, Andrej; Filipuzzi, Marco; Filthaut, Frank; Fincke-Keeler, Margret; Finelli, Kevin Daniel; Fiolhais, Miguel; Fiorini, Luca; Firan, Ana; Fischer, Adam; Fischer, Julia; Fisher, Wade Cameron; Fitzgerald, Eric Andrew; Flechl, Martin; Fleck, Ivor; Fleischmann, Philipp; Fleischmann, Sebastian; Fletcher, Gareth Thomas; Fletcher, Gregory; Flick, Tobias; Floderus, Anders; Flores Castillo, Luis; Flowerdew, Michael; Formica, Andrea; Forti, Alessandra; Fortin, Dominique; Fournier, Daniel; Fox, Harald; Fracchia, Silvia; Francavilla, Paolo; Franchini, Matteo; Franchino, Silvia; Francis, David; Franconi, Laura; Franklin, Melissa; Franz, Sebastien; Fraternali, Marco; French, Sky; Friedrich, Conrad; Friedrich, Felix; Froidevaux, Daniel; Frost, James; Fukunaga, Chikara; Fullana Torregrosa, Esteban; Fulsom, Bryan Gregory; Fuster, Juan; Gabaldon, Carolina; Gabizon, Ofir; Gabrielli, Alessandro; Gabrielli, Andrea; Gadatsch, Stefan; Gadomski, Szymon; Gagliardi, Guido; Gagnon, Pauline; Galea, Cristina; Galhardo, Bruno; Gallas, Elizabeth; Gallo, Valentina Santina; Gallop, Bruce; Gallus, Petr; Galster, Gorm Aske Gram Krohn; Gan, KK; Gao, Jun; Gao, Yongsheng; Garay Walls, Francisca; Garberson, Ford; García, Carmen; García Navarro, José Enrique; Garcia-Sciveres, Maurice; Gardner, Robert; Garelli, Nicoletta; Garonne, Vincent; Gatti, Claudio; Gaudio, Gabriella; Gaur, Bakul; Gauthier, Lea; Gauzzi, Paolo; Gavrilenko, Igor; Gay, Colin; Gaycken, Goetz; Gazis, Evangelos; Ge, Peng; Gecse, Zoltan; Gee, Norman; Geerts, Daniël Alphonsus Adrianus; Geich-Gimbel, Christoph; Gellerstedt, Karl; Gemme, Claudia; Gemmell, Alistair; Genest, Marie-Hélène; Gentile, Simonetta; George, Matthias; George, Simon; Gerbaudo, Davide; Gershon, Avi; Ghazlane, Hamid; Ghodbane, Nabil; Giacobbe, Benedetto; Giagu, Stefano; Giangiobbe, Vincent; Giannetti, Paola; Gianotti, Fabiola; Gibbard, Bruce; Gibson, Stephen; Gilchriese, Murdock; Gillam, Thomas; Gillberg, Dag; Gilles, Geoffrey; Gingrich, Douglas; Giokaris, Nikos; Giordani, MarioPaolo; Giordano, Raffaele; Giorgi, Filippo Maria; Giorgi, Francesco Michelangelo; Giraud, Pierre-Francois; Giugni, Danilo; Giuliani, Claudia; Giulini, Maddalena; Gjelsten, Børge Kile; Gkaitatzis, Stamatios; Gkialas, Ioannis; Gkougkousis, Evangelos Leonidas; Gladilin, Leonid; Glasman, Claudia; Glatzer, Julian; Glaysher, Paul; Glazov, Alexandre; Glonti, George; Goblirsch-Kolb, Maximilian; Goddard, Jack Robert; Godlewski, Jan; Goeringer, Christian; Goldfarb, Steven; Golling, Tobias; Golubkov, Dmitry; Gomes, Agostinho; Gomez Fajardo, Luz Stella; Gonçalo, Ricardo; Goncalves Pinto Firmino Da Costa, Joao; Gonella, Laura; González de la Hoz, Santiago; Gonzalez Parra, Garoe; Gonzalez-Sevilla, Sergio; Goossens, Luc; Gorbounov, Petr Andreevich; Gordon, Howard; Gorelov, Igor; Gorini, Benedetto; Gorini, Edoardo; Gorišek, Andrej; Gornicki, Edward; Goshaw, Alfred; Gössling, Claus; Gostkin, Mikhail Ivanovitch; Gouighri, Mohamed; Goujdami, Driss; Goulette, Marc Phillippe; Goussiou, Anna; Goy, Corinne; Grabas, Herve Marie Xavier; Graber, Lars; Grabowska-Bold, Iwona; Grafström, Per; Grahn, Karl-Johan; Gramling, Johanna; Gramstad, Eirik; Grancagnolo, Sergio; Grassi, Valerio; Gratchev, Vadim; Gray, Heather; Graziani, Enrico; Grebenyuk, Oleg; Greenwood, Zeno Dixon; Gregersen, Kristian; Gregor, Ingrid-Maria; Grenier, Philippe; Griffiths, Justin; Grillo, Alexander; Grimm, Kathryn; Grinstein, Sebastian; Gris, Philippe Luc Yves; Grishkevich, Yaroslav; Grivaz, Jean-Francois; Grohs, Johannes Philipp; Grohsjean, Alexander; Gross, Eilam; Grosse-Knetter, Joern; Grossi, Giulio Cornelio; Groth-Jensen, Jacob; Grout, Zara Jane; Guan, Liang; Guenther, Jaroslav; Guescini, Francesco; Guest, Daniel; Gueta, Orel; Guicheney, Christophe; Guido, Elisa; Guillemin, Thibault; Guindon, Stefan; Gul, Umar; Gumpert, Christian; Guo, Jun; Gupta, Shaun; Gutierrez, Phillip; Gutierrez Ortiz, Nicolas Gilberto; Gutschow, Christian; Guttman, Nir; Guyot, Claude; Gwenlan, Claire; Gwilliam, Carl; Haas, Andy; Haber, Carl; Hadavand, Haleh Khani; Haddad, Nacim; Haefner, Petra; Hageböck, Stephan; Hajduk, Zbigniew; Hakobyan, Hrachya; Haleem, Mahsana; Hall, David; Halladjian, Garabed; Hallewell, Gregory David; Hamacher, Klaus; Hamal, Petr; Hamano, Kenji; Hamer, Matthias; Hamilton, Andrew; Hamilton, Samuel; Hamity, Guillermo Nicolas; Hamnett, Phillip George; Han, Liang; Hanagaki, Kazunori; Hanawa, Keita; Hance, Michael; Hanke, Paul; Hanna, Remie; Hansen, Jørgen Beck; Hansen, Jorn Dines; Hansen, Peter Henrik; Hara, Kazuhiko; Hard, Andrew; Harenberg, Torsten; Hariri, Faten; Harkusha, Siarhei; Harper, Devin; Harrington, Robert; Harris, Orin; Harrison, Paul Fraser; Hartjes, Fred; Hasegawa, Makoto; Hasegawa, Satoshi; Hasegawa, Yoji; Hasib, A; Hassani, Samira; Haug, Sigve; Hauschild, Michael; Hauser, Reiner; Havranek, Miroslav; Hawkes, Christopher; Hawkings, Richard John; Hawkins, Anthony David; Hayashi, Takayasu; Hayden, Daniel; Hays, Chris; Hays, Jonathan Michael; Hayward, Helen; Haywood, Stephen; Head, Simon; Heck, Tobias; Hedberg, Vincent; Heelan, Louise; Heim, Sarah; Heim, Timon; Heinemann, Beate; Heinrich, Lukas; Hejbal, Jiri; Helary, Louis; Heller, Claudio; Heller, Matthieu; Hellman, Sten; Hellmich, Dennis; Helsens, Clement; Henderson, James; Henderson, Robert; Heng, Yang; Hengler, Christopher; Henrichs, Anna; Henriques Correia, Ana Maria; Henrot-Versille, Sophie; Herbert, Geoffrey Henry; Hernández Jiménez, Yesenia; Herrberg-Schubert, Ruth; Herten, Gregor; Hertenberger, Ralf; Hervas, Luis; Hesketh, Gavin Grant; Hessey, Nigel; Hickling, Robert; Higón-Rodriguez, Emilio; Hill, Ewan; Hill, John; Hiller, Karl Heinz; Hillert, Sonja; Hillier, Stephen; Hinchliffe, Ian; Hines, Elizabeth; Hirose, Minoru; Hirschbuehl, Dominic; Hobbs, John; Hod, Noam; Hodgkinson, Mark; Hodgson, Paul; Hoecker, Andreas; Hoeferkamp, Martin; Hoenig, Friedrich; Hoffmann, Dirk; Hohlfeld, Marc; Holmes, Tova Ray; Hong, Tae Min; Hooft van Huysduynen, Loek; Hopkins, Walter; Horii, Yasuyuki; Hostachy, Jean-Yves; Hou, Suen; Hoummada, Abdeslam; Howard, Jacob; Howarth, James; Hrabovsky, Miroslav; Hristova, Ivana; Hrivnac, Julius; Hryn'ova, Tetiana; Hsu, Catherine; Hsu, Pai-hsien Jennifer; Hsu, Shih-Chieh; Hu, Diedi; Hu, Xueye; Huang, Yanping; Hubacek, Zdenek; Hubaut, Fabrice; Huegging, Fabian; Huffman, Todd Brian; Hughes, Emlyn; Hughes, Gareth; Huhtinen, Mika; Hülsing, Tobias Alexander; Hurwitz, Martina; Huseynov, Nazim; Huston, Joey; Huth, John; Iacobucci, Giuseppe; Iakovidis, Georgios; Ibragimov, Iskander; Iconomidou-Fayard, Lydia; Ideal, Emma; Idrissi, Zineb; Iengo, Paolo; Igonkina, Olga; Iizawa, Tomoya; Ikegami, Yoichi; Ikematsu, Katsumasa; Ikeno, Masahiro; Ilchenko, Iurii; Iliadis, Dimitrios; Ilic, Nikolina; Inamaru, Yuki; Ince, Tayfun; Ioannou, Pavlos; Iodice, Mauro; Iordanidou, Kalliopi; Ippolito, Valerio; Irles Quiles, Adrian; Isaksson, Charlie; Ishino, Masaya; Ishitsuka, Masaki; Ishmukhametov, Renat; Issever, Cigdem; Istin, Serhat; Iturbe Ponce, Julia Mariana; Iuppa, Roberto; Ivarsson, Jenny; Iwanski, Wieslaw; Iwasaki, Hiroyuki; Izen, Joseph; Izzo, Vincenzo; Jackson, Brett; Jackson, Matthew; Jackson, Paul; Jaekel, Martin; Jain, Vivek; Jakobs, Karl; Jakobsen, Sune; Jakoubek, Tomas; Jakubek, Jan; Jamin, David Olivier; Jana, Dilip; Jansen, Eric; Jansen, Hendrik; Janssen, Jens; Janus, Michel; Jarlskog, Göran; Javadov, Namig; Javůrek, Tomáš; Jeanty, Laura; Jejelava, Juansher; Jeng, Geng-yuan; Jennens, David; Jenni, Peter; Jentzsch, Jennifer; Jeske, Carl; Jézéquel, Stéphane; Ji, Haoshuang; Jia, Jiangyong; Jiang, Yi; Jimenez Belenguer, Marcos; Jin, Shan; Jinaru, Adam; Jinnouchi, Osamu; Joergensen, Morten Dam; Johansson, Erik; Johansson, Per; Johns, Kenneth; Jon-And, Kerstin; Jones, Graham; Jones, Roger; Jones, Tim; Jongmanns, Jan; Jorge, Pedro; Joshi, Kiran Daniel; Jovicevic, Jelena; Ju, Xiangyang; Jung, Christian; Jungst, Ralph Markus; Jussel, Patrick; Juste Rozas, Aurelio; Kaci, Mohammed; Kaczmarska, Anna; Kado, Marumi; Kagan, Harris; Kagan, Michael; Kajomovitz, Enrique; Kalderon, Charles William; Kama, Sami; Kamenshchikov, Andrey; Kanaya, Naoko; Kaneda, Michiru; Kaneti, Steven; Kantserov, Vadim; Kanzaki, Junichi; Kaplan, Benjamin; Kapliy, Anton; Kar, Deepak; Karakostas, Konstantinos; Karastathis, Nikolaos; Kareem, Mohammad Jawad; Karnevskiy, Mikhail; Karpov, Sergey; Karpova, Zoya; Karthik, Krishnaiyengar; Kartvelishvili, Vakhtang; Karyukhin, Andrey; Kashif, Lashkar; Kasieczka, Gregor; Kass, Richard; Kastanas, Alex; Kataoka, Yousuke; Katre, Akshay; Katzy, Judith; Kaushik, Venkatesh; Kawagoe, Kiyotomo; Kawamoto, Tatsuo; Kawamura, Gen; Kazama, Shingo; Kazanin, Vassili; Kazarinov, Makhail; Keeler, Richard; Kehoe, Robert; Keil, Markus; Keller, John; Kempster, Jacob Julian; Keoshkerian, Houry; Kepka, Oldrich; Kerševan, Borut Paul; Kersten, Susanne; Kessoku, Kohei; Keung, Justin; Keyes, Robert; Khalil-zada, Farkhad; Khandanyan, Hovhannes; Khanov, Alexander; Kharlamov, Alexey; Khodinov, Alexander; Khomich, Andrei; Khoo, Teng Jian; Khoriauli, Gia; Khoroshilov, Andrey; Khovanskiy, Valery; Khramov, Evgeniy; Khubua, Jemal; Kim, Hee Yeun; Kim, Hyeon Jin; Kim, Shinhong; Kimura, Naoki; Kind, Oliver; King, Barry; King, Matthew; King, Robert Steven Beaufoy; King, Samuel Burton; Kirk, Julie; Kiryunin, Andrey; Kishimoto, Tomoe; Kisielewska, Danuta; Kiss, Florian; Kiuchi, Kenji; Kladiva, Eduard; Klein, Max; Klein, Uta; Kleinknecht, Konrad; Klimek, Pawel; Klimentov, Alexei; Klingenberg, Reiner; Klinger, Joel Alexander; Klioutchnikova, Tatiana; Klok, Peter; Kluge, Eike-Erik; Kluit, Peter; Kluth, Stefan; Kneringer, Emmerich; Knoops, Edith; Knue, Andrea; Kobayashi, Dai; Kobayashi, Tomio; Kobel, Michael; Kocian, Martin; Kodys, Peter; Koffas, Thomas; Koffeman, Els; Kogan, Lucy Anne; Kohlmann, Simon; Kohout, Zdenek; Kohriki, Takashi; Koi, Tatsumi; Kolanoski, Hermann; Koletsou, Iro; Koll, James; Komar, Aston; Komori, Yuto; Kondo, Takahiko; Kondrashova, Nataliia; Köneke, Karsten; König, Adriaan; König, Sebastian; Kono, Takanori; Konoplich, Rostislav; Konstantinidis, Nikolaos; Kopeliansky, Revital; Koperny, Stefan; Köpke, Lutz; Kopp, Anna Katharina; Korcyl, Krzysztof; Kordas, Kostantinos; Korn, Andreas; Korol, Aleksandr; Korolkov, Ilya; Korolkova, Elena; Korotkov, Vladislav; Kortner, Oliver; Kortner, Sandra; Kostyukhin, Vadim; Kotov, Vladislav; Kotwal, Ashutosh; Kourkoumeli-Charalampidi, Athina; Kourkoumelis, Christine; Kouskoura, Vasiliki; Koutsman, Alex; Kowalewski, Robert Victor; Kowalski, Tadeusz; Kozanecki, Witold; Kozhin, Anatoly; Kramarenko, Viktor; Kramberger, Gregor; Krasnopevtsev, Dimitriy; Krasny, Mieczyslaw Witold; Krasznahorkay, Attila; Kraus, Jana; Kravchenko, Anton; Kreiss, Sven; Kretz, Moritz; Kretzschmar, Jan; Kreutzfeldt, Kristof; Krieger, Peter; Kroeninger, Kevin; Kroha, Hubert; Kroll, Joe; Kroseberg, Juergen; Krstic, Jelena; Kruchonak, Uladzimir; Krüger, Hans; Kruker, Tobias; Krumnack, Nils; Krumshteyn, Zinovii; Kruse, Amanda; Kruse, Mark; Kruskal, Michael; Kubota, Takashi; Kucuk, Hilal; Kuday, Sinan; Kuehn, Susanne; Kugel, Andreas; Kuhl, Andrew; Kuhl, Thorsten; Kukhtin, Victor; Kulchitsky, Yuri; Kuleshov, Sergey; Kuna, Marine; Kunigo, Takuto; Kupco, Alexander; Kurashige, Hisaya; Kurochkin, Yurii; Kurumida, Rie; Kus, Vlastimil; Kuwertz, Emma Sian; Kuze, Masahiro; Kvita, Jiri; La Rosa, Alessandro; La Rotonda, Laura; Lacasta, Carlos; Lacava, Francesco; Lacey, James; Lacker, Heiko; Lacour, Didier; Lacuesta, Vicente Ramón; Ladygin, Evgueni; Lafaye, Remi; Laforge, Bertrand; Lagouri, Theodota; Lai, Stanley; Laier, Heiko; Lambourne, Luke; Lammers, Sabine; Lampen, Caleb; Lampl, Walter; Lançon, Eric; Landgraf, Ulrich; Landon, Murrough; Lang, Valerie Susanne; Lankford, Andrew; Lanni, Francesco; Lantzsch, Kerstin; Laplace, Sandrine; Lapoire, Cecile; Laporte, Jean-Francois; Lari, Tommaso; Lasagni Manghi, Federico; Lassnig, Mario; Laurelli, Paolo; Lavrijsen, Wim; Law, Alexander; Laycock, Paul; Le Dortz, Olivier; Le Guirriec, Emmanuel; Le Menedeu, Eve; LeCompte, Thomas; Ledroit-Guillon, Fabienne Agnes Marie; Lee, Claire Alexandra; Lee, Hurng-Chun; Lee, Jason; Lee, Shih-Chang; Lee, Lawrence; Lefebvre, Guillaume; Lefebvre, Michel; Legger, Federica; Leggett, Charles; Lehan, Allan; Lehmann Miotto, Giovanna; Lei, Xiaowen; Leight, William Axel; Leisos, Antonios; Leister, Andrew Gerard; Leite, Marco Aurelio Lisboa; Leitner, Rupert; Lellouch, Daniel; Lemmer, Boris; Leney, Katharine; Lenz, Tatjana; Lenzen, Georg; Lenzi, Bruno; Leone, Robert; Leone, Sandra; Leonidopoulos, Christos; Leontsinis, Stefanos; Leroy, Claude; Lester, Christopher; Lester, Christopher Michael; Levchenko, Mikhail; Levêque, Jessica; Levin, Daniel; Levinson, Lorne; Levy, Mark; Lewis, Adrian; Lewis, George; Leyko, Agnieszka; Leyton, Michael; Li, Bing; Li, Bo; Li, Haifeng; Li, Ho Ling; Li, Lei; Li, Liang; Li, Shu; Li, Yichen; Liang, Zhijun; Liao, Hongbo; Liberti, Barbara; Lichard, Peter; Lie, Ki; Liebal, Jessica; Liebig, Wolfgang; Limbach, Christian; Limosani, Antonio; Lin, Simon; Lin, Tai-Hua; Linde, Frank; Lindquist, Brian Edward; Linnemann, James; Lipeles, Elliot; Lipniacka, Anna; Lisovyi, Mykhailo; Liss, Tony; Lissauer, David; Lister, Alison; Litke, Alan; Liu, Bo; Liu, Dong; Liu, Jianbei; Liu, Kun; Liu, Lulu; Liu, Miaoyuan; Liu, Minghui; Liu, Yanwen; Livan, Michele; Lleres, Annick; Llorente Merino, Javier; Lloyd, Stephen; Lo Sterzo, Francesco; Lobodzinska, Ewelina; Loch, Peter; Lockman, William; Loebinger, Fred; Loevschall-Jensen, Ask Emil; Loginov, Andrey; Lohse, Thomas; Lohwasser, Kristin; Lokajicek, Milos; Lombardo, Vincenzo Paolo; Long, Brian Alexander; Long, Jonathan; Long, Robin Eamonn; Lopes, Lourenco; Lopez Mateos, David; Lopez Paredes, Brais; Lopez Paz, Ivan; Lorenz, Jeanette; Lorenzo Martinez, Narei; Losada, Marta; Loscutoff, Peter; Lou, XinChou; Lounis, Abdenour; Love, Jeremy; Love, Peter; Lowe, Andrew; Lu, Feng; Lu, Nan; Lubatti, Henry; Luci, Claudio; Lucotte, Arnaud; Luehring, Frederick; Lukas, Wolfgang; Luminari, Lamberto; Lundberg, Olof; Lund-Jensen, Bengt; Lungwitz, Matthias; Lynn, David; Lysak, Roman; Lytken, Else; Ma, Hong; Ma, Lian Liang; Maccarrone, Giovanni; Macchiolo, Anna; Machado Miguens, Joana; Macina, Daniela; Madaffari, Daniele; Madar, Romain; Maddocks, Harvey Jonathan; Mader, Wolfgang; Madsen, Alexander; Maeno, Mayuko; Maeno, Tadashi; Maevskiy, Artem; Magradze, Erekle; Mahboubi, Kambiz; Mahlstedt, Joern; Mahmoud, Sara; Maiani, Camilla; Maidantchik, Carmen; Maier, Andreas Alexander; Maio, Amélia; Majewski, Stephanie; Makida, Yasuhiro; Makovec, Nikola; Mal, Prolay; Malaescu, Bogdan; Malecki, Pawel; Maleev, Victor; Malek, Fairouz; Mallik, Usha; Malon, David; Malone, Caitlin; Maltezos, Stavros; Malyshev, Vladimir; Malyukov, Sergei; Mamuzic, Judita; Mandelli, Beatrice; Mandelli, Luciano; Mandić, Igor; Mandrysch, Rocco; Maneira, José; Manfredini, Alessandro; Manhaes de Andrade Filho, Luciano; Manjarres Ramos, Joany Andreina; Mann, Alexander; Manning, Peter; Manousakis-Katsikakis, Arkadios; Mansoulie, Bruno; Mantifel, Rodger; Mapelli, Livio; March, Luis; Marchand, Jean-Francois; Marchiori, Giovanni; Marcisovsky, Michal; Marino, Christopher; Marjanovic, Marija; Marroquim, Fernando; Marsden, Stephen Philip; Marshall, Zach; Marti, Lukas Fritz; Marti-Garcia, Salvador; Martin, Brian; Martin, Brian Thomas; Martin, Tim; Martin, Victoria Jane; Martin dit Latour, Bertrand; Martinez, Homero; Martinez, Mario; Martin-Haugh, Stewart; Martyniuk, Alex; Marx, Marilyn; Marzano, Francesco; Marzin, Antoine; Masetti, Lucia; Mashimo, Tetsuro; Mashinistov, Ruslan; Masik, Jiri; Maslennikov, Alexey; Massa, Ignazio; Massa, Lorenzo; Massol, Nicolas; Mastrandrea, Paolo; Mastroberardino, Anna; Masubuchi, Tatsuya; Mättig, Peter; Mattmann, Johannes; Maurer, Julien; Maxfield, Stephen; Maximov, Dmitriy; Mazini, Rachid; Mazzaferro, Luca; Mc Goldrick, Garrin; Mc Kee, Shawn Patrick; McCarn, Allison; McCarthy, Robert; McCarthy, Tom; McCubbin, Norman; McFarlane, Kenneth; Mcfayden, Josh; Mchedlidze, Gvantsa; McMahon, Steve; McPherson, Robert; Mechnich, Joerg; Medinnis, Michael; Meehan, Samuel; Mehlhase, Sascha; Mehta, Andrew; Meier, Karlheinz; Meineck, Christian; Meirose, Bernhard; Melachrinos, Constantinos; Mellado Garcia, Bruce Rafael; Meloni, Federico; Mengarelli, Alberto; Menke, Sven; Meoni, Evelin; Mercurio, Kevin Michael; Mergelmeyer, Sebastian; Meric, Nicolas; Mermod, Philippe; Merola, Leonardo; Meroni, Chiara; Merritt, Frank; Merritt, Hayes; Messina, Andrea; Metcalfe, Jessica; Mete, Alaettin Serhan; Meyer, Carsten; Meyer, Christopher; Meyer, Jean-Pierre; Meyer, Jochen; Middleton, Robin; Migas, Sylwia; Mijović, Liza; Mikenberg, Giora; Mikestikova, Marcela; Mikuž, Marko; Milic, Adriana; Miller, David; Mills, Corrinne; Milov, Alexander; Milstead, David; Minaenko, Andrey; Minami, Yuto; Minashvili, Irakli; Mincer, Allen; Mindur, Bartosz; Mineev, Mikhail; Ming, Yao; Mir, Lluisa-Maria; Mirabelli, Giovanni; Mitani, Takashi; Mitrevski, Jovan; Mitsou, Vasiliki A; Miucci, Antonio; Miyagawa, Paul; Mjörnmark, Jan-Ulf; Moa, Torbjoern; Mochizuki, Kazuya; Mohapatra, Soumya; Mohr, Wolfgang; Molander, Simon; Moles-Valls, Regina; Mönig, Klaus; Monini, Caterina; Monk, James; Monnier, Emmanuel; Montejo Berlingen, Javier; Monticelli, Fernando; Monzani, Simone; Moore, Roger; Morange, Nicolas; Moreno, Deywis; Moreno Llácer, María; Morettini, Paolo; Morgenstern, Marcus; Morii, Masahiro; Morisbak, Vanja; Moritz, Sebastian; Morley, Anthony Keith; Mornacchi, Giuseppe; Morris, John; Morvaj, Ljiljana; Moser, Hans-Guenther; Mosidze, Maia; Moss, Josh; Motohashi, Kazuki; Mount, Richard; Mountricha, Eleni; Mouraviev, Sergei; Moyse, Edward; Muanza, Steve; Mudd, Richard; Mueller, Felix; Mueller, James; Mueller, Klemens; Mueller, Thibaut; Mueller, Timo; Muenstermann, Daniel; Munwes, Yonathan; Murillo Quijada, Javier Alberto; Murray, Bill; Musheghyan, Haykuhi; Musto, Elisa; Myagkov, Alexey; Myska, Miroslav; Nackenhorst, Olaf; Nadal, Jordi; Nagai, Koichi; Nagai, Ryo; Nagai, Yoshikazu; Nagano, Kunihiro; Nagarkar, Advait; Nagasaka, Yasushi; Nagata, Kazuki; Nagel, Martin; Nairz, Armin Michael; Nakahama, Yu; Nakamura, Koji; Nakamura, Tomoaki; Nakano, Itsuo; Namasivayam, Harisankar; Nanava, Gizo; Naranjo Garcia, Roger Felipe; Narayan, Rohin; Nattermann, Till; Naumann, Thomas; Navarro, Gabriela; Nayyar, Ruchika; Neal, Homer; Nechaeva, Polina; Neep, Thomas James; Nef, Pascal Daniel; Negri, Andrea; Negri, Guido; Negrini, Matteo; Nektarijevic, Snezana; Nellist, Clara; Nelson, Andrew; Nelson, Timothy Knight; Nemecek, Stanislav; Nemethy, Peter; Nepomuceno, Andre Asevedo; Nessi, Marzio; Neubauer, Mark; Neumann, Manuel; Neves, Ricardo; Nevski, Pavel; Newman, Paul; Nguyen, Duong Hai; Nickerson, Richard; Nicolaidou, Rosy; Nicquevert, Bertrand; Nielsen, Jason; Nikiforou, Nikiforos; Nikiforov, Andriy; Nikolaenko, Vladimir; Nikolic-Audit, Irena; Nikolics, Katalin; Nikolopoulos, Konstantinos; Nilsson, Paul; Ninomiya, Yoichi; Nisati, Aleandro; Nisius, Richard; Nobe, Takuya; Nodulman, Lawrence; Nomachi, Masaharu; Nomidis, Ioannis; Norberg, Scarlet; Nordberg, Markus; Novgorodova, Olga; Nowak, Sebastian; Nozaki, Mitsuaki; Nozka, Libor; Ntekas, Konstantinos; Nunes Hanninger, Guilherme; Nunnemann, Thomas; Nurse, Emily; Nuti, Francesco; O'Brien, Brendan Joseph; O'grady, Fionnbarr; O'Neil, Dugan; O'Shea, Val; Oakham, Gerald; Oberlack, Horst; Obermann, Theresa; Ocariz, Jose; Ochi, Atsuhiko; Ochoa, Ines; Oda, Susumu; Odaka, Shigeru; Ogren, Harold; Oh, Alexander; Oh, Seog; Ohm, Christian; Ohman, Henrik; Oide, Hideyuki; Okamura, Wataru; Okawa, Hideki; Okumura, Yasuyuki; Okuyama, Toyonobu; Olariu, Albert; Olchevski, Alexander; Olivares Pino, Sebastian Andres; Oliveira Damazio, Denis; Oliver Garcia, Elena; Olszewski, Andrzej; Olszowska, Jolanta; Onofre, António; Onyisi, Peter; Oram, Christopher; Oreglia, Mark; Oren, Yona; Orestano, Domizia; Orlando, Nicola; Oropeza Barrera, Cristina; Orr, Robert; Osculati, Bianca; Ospanov, Rustem; Otero y Garzon, Gustavo; Otono, Hidetoshi; Ouchrif, Mohamed; Ouellette, Eric; Ould-Saada, Farid; Ouraou, Ahmimed; Oussoren, Koen Pieter; Ouyang, Qun; Ovcharova, Ana; Owen, Mark; Ozcan, Veysi Erkcan; Ozturk, Nurcan; Pachal, Katherine; Pacheco Pages, Andres; Padilla Aranda, Cristobal; Pagáčová, Martina; Pagan Griso, Simone; Paganis, Efstathios; Pahl, Christoph; Paige, Frank; Pais, Preema; Pajchel, Katarina; Palacino, Gabriel; Palestini, Sandro; Palka, Marek; Pallin, Dominique; Palma, Alberto; Palmer, Jody; Pan, Yibin; Panagiotopoulou, Evgenia; Panduro Vazquez, William; Pani, Priscilla; Panikashvili, Natalia; Panitkin, Sergey; Pantea, Dan; Paolozzi, Lorenzo; Papadopoulou, Theodora; Papageorgiou, Konstantinos; Paramonov, Alexander; Paredes Hernandez, Daniela; Parker, Michael Andrew; Parodi, Fabrizio; Parsons, John; Parzefall, Ulrich; Pasqualucci, Enrico; Passaggio, Stefano; Passeri, Antonio; Pastore, Fernanda; Pastore, Francesca; Pásztor, Gabriella; Pataraia, Sophio; Patel, Nikhul; Pater, Joleen; Patricelli, Sergio; Pauly, Thilo; Pearce, James; Pedersen, Lars Egholm; Pedersen, Maiken; Pedraza Lopez, Sebastian; Pedro, Rute; Peleganchuk, Sergey; Pelikan, Daniel; Peng, Haiping; Penning, Bjoern; Penwell, John; Perepelitsa, Dennis; Perez Codina, Estel; Pérez García-Estañ, María Teresa; Perini, Laura; Pernegger, Heinz; Perrella, Sabrina; Perrino, Roberto; Peschke, Richard; Peshekhonov, Vladimir; Peters, Krisztian; Peters, Yvonne; Petersen, Brian; Petersen, Troels; Petit, Elisabeth; Petridis, Andreas; Petridou, Chariclia; Petrolo, Emilio; Petrucci, Fabrizio; Pettersson, Nora Emilia; Pezoa, Raquel; Phillips, Peter William; Piacquadio, Giacinto; Pianori, Elisabetta; Picazio, Attilio; Piccaro, Elisa; Piccinini, Maurizio; Piegaia, Ricardo; Pignotti, David; Pilcher, James; Pilkington, Andrew; Pina, João Antonio; Pinamonti, Michele; Pinder, Alex; Pinfold, James; Pingel, Almut; Pinto, Belmiro; Pires, Sylvestre; Pitt, Michael; Pizio, Caterina; Plazak, Lukas; Pleier, Marc-Andre; Pleskot, Vojtech; Plotnikova, Elena; Plucinski, Pawel; Pluth, Daniel; Poddar, Sahill; Podlyski, Fabrice; Poettgen, Ruth; Poggioli, Luc; Pohl, David-leon; Pohl, Martin; Polesello, Giacomo; Policicchio, Antonio; Polifka, Richard; Polini, Alessandro; Pollard, Christopher Samuel; Polychronakos, Venetios; Pommès, Kathy; Pontecorvo, Ludovico; Pope, Bernard; Popeneciu, Gabriel Alexandru; Popovic, Dragan; Poppleton, Alan; Portell Bueso, Xavier; Pospisil, Stanislav; Potamianos, Karolos; Potrap, Igor; Potter, Christina; Potter, Christopher; Poulard, Gilbert; Poveda, Joaquin; Pozdnyakov, Valery; Pralavorio, Pascal; Pranko, Aliaksandr; Prasad, Srivas; Pravahan, Rishiraj; Prell, Soeren; Price, Darren; Price, Joe; Price, Lawrence; Prieur, Damien; Primavera, Margherita; Proissl, Manuel; Prokofiev, Kirill; Prokoshin, Fedor; Protopapadaki, Eftychia-sofia; Protopopescu, Serban; Proudfoot, James; Przybycien, Mariusz; Przysiezniak, Helenka; Ptacek, Elizabeth; Puddu, Daniele; Pueschel, Elisa; Puldon, David; Purohit, Milind; Puzo, Patrick; Qian, Jianming; Qin, Gang; Qin, Yang; Quadt, Arnulf; Quarrie, David; Quayle, William; Queitsch-Maitland, Michaela; Quilty, Donnchadha; Qureshi, Anum; Radeka, Veljko; Radescu, Voica; Radhakrishnan, Sooraj Krishnan; Radloff, Peter; Rados, Pere; Ragusa, Francesco; Rahal, Ghita; Rajagopalan, Srinivasan; Rammensee, Michael; Randle-Conde, Aidan Sean; Rangel-Smith, Camila; Rao, Kanury; Rauscher, Felix; Rave, Tobias Christian; Ravenscroft, Thomas; Raymond, Michel; Read, Alexander Lincoln; Readioff, Nathan Peter; Rebuzzi, Daniela; Redelbach, Andreas; Redlinger, George; Reece, Ryan; Reeves, Kendall; Rehnisch, Laura; Reisin, Hernan; Relich, Matthew; Rembser, Christoph; Ren, Huan; Ren, Zhongliang; Renaud, Adrien; Rescigno, Marco; Resconi, Silvia; Rezanova, Olga; Reznicek, Pavel; Rezvani, Reyhaneh; Richter, Robert; Ridel, Melissa; Rieck, Patrick; Rieger, Julia; Rijssenbeek, Michael; Rimoldi, Adele; Rinaldi, Lorenzo; Ritsch, Elmar; Riu, Imma; Rizatdinova, Flera; Rizvi, Eram; Robertson, Steven; Robichaud-Veronneau, Andree; Robinson, Dave; Robinson, James; Robson, Aidan; Roda, Chiara; Rodrigues, Luis; Roe, Shaun; Røhne, Ole; Rolli, Simona; Romaniouk, Anatoli; Romano, Marino; Romero Adam, Elena; Rompotis, Nikolaos; Ronzani, Manfredi; Roos, Lydia; Ros, Eduardo; Rosati, Stefano; Rosbach, Kilian; Rose, Matthew; Rose, Peyton; Rosendahl, Peter Lundgaard; Rosenthal, Oliver; Rossetti, Valerio; Rossi, Elvira; Rossi, Leonardo Paolo; Rosten, Rachel; Rotaru, Marina; Roth, Itamar; Rothberg, Joseph; Rousseau, David; Royon, Christophe; Rozanov, Alexandre; Rozen, Yoram; Ruan, Xifeng; Rubbo, Francesco; Rubinskiy, Igor; Rud, Viacheslav; Rudolph, Christian; Rudolph, Matthew Scott; Rühr, Frederik; Ruiz-Martinez, Aranzazu; Rurikova, Zuzana; Rusakovich, Nikolai; Ruschke, Alexander; Rutherfoord, John; Ruthmann, Nils; Ryabov, Yury; Rybar, Martin; Rybkin, Grigori; Ryder, Nick; Saavedra, Aldo; Sabato, Gabriele; Sacerdoti, Sabrina; Saddique, Asif; Sadeh, Iftach; Sadrozinski, Hartmut; Sadykov, Renat; Safai Tehrani, Francesco; Sakamoto, Hiroshi; Sakurai, Yuki; Salamanna, Giuseppe; Salamon, Andrea; Saleem, Muhammad; Salek, David; Sales De Bruin, Pedro Henrique; Salihagic, Denis; Salnikov, Andrei; Salt, José; Salvatore, Daniela; Salvatore, Pasquale Fabrizio; Salvucci, Antonio; Salzburger, Andreas; Sampsonidis, Dimitrios; Sanchez, Arturo; Sánchez, Javier; Sanchez Martinez, Victoria; Sandaker, Heidi; Sandbach, Ruth Laura; Sander, Heinz Georg; Sanders, Michiel; Sandhoff, Marisa; Sandoval, Tanya; Sandoval, Carlos; Sandstroem, Rikard; Sankey, Dave; Sansoni, Andrea; Santoni, Claudio; Santonico, Rinaldo; Santos, Helena; Santoyo Castillo, Itzebelt; Sapp, Kevin; Sapronov, Andrey; Saraiva, João; Sarrazin, Bjorn; Sartisohn, Georg; Sasaki, Osamu; Sasaki, Yuichi; Sauvage, Gilles; Sauvan, Emmanuel; Savard, Pierre; Savu, Dan Octavian; Sawyer, Craig; Sawyer, Lee; Saxon, David; Saxon, James; Sbarra, Carla; Sbrizzi, Antonio; Scanlon, Tim; Scannicchio, Diana; Scarcella, Mark; Scarfone, Valerio; Schaarschmidt, Jana; Schacht, Peter; Schaefer, Douglas; Schaefer, Ralph; Schaepe, Steffen; Schaetzel, Sebastian; Schäfer, Uli; Schaffer, Arthur; Schaile, Dorothee; Schamberger, R~Dean; Scharf, Veit; Schegelsky, Valery; Scheirich, Daniel; Schernau, Michael; Scherzer, Max; Schiavi, Carlo; Schieck, Jochen; Schillo, Christian; Schioppa, Marco; Schlenker, Stefan; Schmidt, Evelyn; Schmieden, Kristof; Schmitt, Christian; Schmitt, Sebastian; Schneider, Basil; Schnellbach, Yan Jie; Schnoor, Ulrike; Schoeffel, Laurent; Schoening, Andre; Schoenrock, Bradley Daniel; Schorlemmer, Andre Lukas; Schott, Matthias; Schouten, Doug; Schovancova, Jaroslava; Schramm, Steven; Schreyer, Manuel; Schroeder, Christian; Schuh, Natascha; Schultens, Martin Johannes; Schultz-Coulon, Hans-Christian; Schulz, Holger; Schumacher, Markus; Schumm, Bruce; Schune, Philippe; Schwanenberger, Christian; Schwartzman, Ariel; Schwarz, Thomas Andrew; Schwegler, Philipp; Schwemling, Philippe; Schwienhorst, Reinhard; Schwindling, Jerome; Schwindt, Thomas; Schwoerer, Maud; Sciacca, Gianfranco; Scifo, Estelle; Sciolla, Gabriella; Scuri, Fabrizio; Scutti, Federico; Searcy, Jacob; Sedov, George; Sedykh, Evgeny; Seema, Pienpen; Seidel, Sally; Seiden, Abraham; Seifert, Frank; Seixas, José; Sekhniaidze, Givi; Sekula, Stephen; Selbach, Karoline Elfriede; Seliverstov, Dmitry; Sellers, Graham; Semprini-Cesari, Nicola; Serfon, Cedric; Serin, Laurent; Serkin, Leonid; Serre, Thomas; Seuster, Rolf; Severini, Horst; Sfiligoj, Tina; Sforza, Federico; Sfyrla, Anna; Shabalina, Elizaveta; Shamim, Mansoora; Shan, Lianyou; Shang, Ruo-yu; Shank, James; Shapiro, Marjorie; Shatalov, Pavel; Shaw, Kate; Shehu, Ciwake Yusufu; Sherwood, Peter; Shi, Liaoshan; Shimizu, Shima; Shimmin, Chase Owen; Shimojima, Makoto; Shiyakova, Mariya; Shmeleva, Alevtina; Shochet, Mel; Short, Daniel; Shrestha, Suyog; Shulga, Evgeny; Shupe, Michael; Shushkevich, Stanislav; Sicho, Petr; Sidiropoulou, Ourania; Sidorov, Dmitri; Sidoti, Antonio; Siegert, Frank; Sijacki, Djordje; Silva, José; Silver, Yiftah; Silverstein, Daniel; Silverstein, Samuel; Simak, Vladislav; Simard, Olivier; Simic, Ljiljana; Simion, Stefan; Simioni, Eduard; Simmons, Brinick; Simon, Dorian; Simoniello, Rosa; Sinervo, Pekka; Sinev, Nikolai; Siragusa, Giovanni; Sircar, Anirvan; Sisakyan, Alexei; Sivoklokov, Serguei; Sjölin, Jörgen; Sjursen, Therese; Skottowe, Hugh Philip; Skovpen, Kirill; Skubic, Patrick; Slater, Mark; Slavicek, Tomas; Slawinska, Magdalena; Sliwa, Krzysztof; Smakhtin, Vladimir; Smart, Ben; Smestad, Lillian; Smirnov, Sergei; Smirnov, Yury; Smirnova, Lidia; Smirnova, Oxana; Smith, Kenway; Smizanska, Maria; Smolek, Karel; Snesarev, Andrei; Snidero, Giacomo; Snyder, Scott; Sobie, Randall; Socher, Felix; Soffer, Abner; Soh, Dart-yin; Solans, Carlos; Solar, Michael; Solc, Jaroslav; Soldatov, Evgeny; Soldevila, Urmila; Solodkov, Alexander; Soloshenko, Alexei; Solovyanov, Oleg; Solovyev, Victor; Sommer, Philip; Song, Hong Ye; Soni, Nitesh; Sood, Alexander; Sopczak, Andre; Sopko, Bruno; Sopko, Vit; Sorin, Veronica; Sosebee, Mark; Soualah, Rachik; Soueid, Paul; Soukharev, Andrey; South, David; Spagnolo, Stefania; Spanò, Francesco; Spearman, William Robert; Spettel, Fabian; Spighi, Roberto; Spigo, Giancarlo; Spiller, Laurence Anthony; Spousta, Martin; Spreitzer, Teresa; St Denis, Richard Dante; Staerz, Steffen; Stahlman, Jonathan; Stamen, Rainer; Stamm, Soren; Stanecka, Ewa; Stanek, Robert; Stanescu, Cristian; Stanescu-Bellu, Madalina; Stanitzki, Marcel Michael; Stapnes, Steinar; Starchenko, Evgeny; Stark, Jan; Staroba, Pavel; Starovoitov, Pavel; Staszewski, Rafal; Stavina, Pavel; Steinberg, Peter; Stelzer, Bernd; Stelzer, Harald Joerg; Stelzer-Chilton, Oliver; Stenzel, Hasko; Stern, Sebastian; Stewart, Graeme; Stillings, Jan Andre; Stockton, Mark; Stoebe, Michael; Stoicea, Gabriel; Stolte, Philipp; Stonjek, Stefan; Stradling, Alden; Straessner, Arno; Stramaglia, Maria Elena; Strandberg, Jonas; Strandberg, Sara; Strandlie, Are; Strauss, Emanuel; Strauss, Michael; Strizenec, Pavol; Ströhmer, Raimund; Strom, David; Stroynowski, Ryszard; Strubig, Antonia; Stucci, Stefania Antonia; Stugu, Bjarne; Styles, Nicholas Adam; Su, Dong; Su, Jun; Subramaniam, Rajivalochan; Succurro, Antonella; Sugaya, Yorihito; Suhr, Chad; Suk, Michal; Sulin, Vladimir; Sultansoy, Saleh; Sumida, Toshi; Sun, Siyuan; Sun, Xiaohu; Sundermann, Jan Erik; Suruliz, Kerim; Susinno, Giancarlo; Sutton, Mark; Suzuki, Yu; Svatos, Michal; Swedish, Stephen; Swiatlowski, Maximilian; Sykora, Ivan; Sykora, Tomas; Ta, Duc; Taccini, Cecilia; Tackmann, Kerstin; Taenzer, Joe; Taffard, Anyes; Tafirout, Reda; Taiblum, Nimrod; Takai, Helio; Takashima, Ryuichi; Takeda, Hiroshi; Takeshita, Tohru; Takubo, Yosuke; Talby, Mossadek; Talyshev, Alexey; Tam, Jason; Tan, Kong Guan; Tanaka, Junichi; Tanaka, Reisaburo; Tanaka, Satoshi; Tanaka, Shuji; Tanasijczuk, Andres Jorge; Tannenwald, Benjamin Bordy; Tannoury, Nancy; Tapprogge, Stefan; Tarem, Shlomit; Tarrade, Fabien; Tartarelli, Giuseppe Francesco; Tas, Petr; Tasevsky, Marek; Tashiro, Takuya; Tassi, Enrico; Tavares Delgado, Ademar; Tayalati, Yahya; Taylor, Frank; Taylor, Geoffrey; Taylor, Wendy; Teischinger, Florian Alfred; Teixeira Dias Castanheira, Matilde; Teixeira-Dias, Pedro; Temming, Kim Katrin; Ten Kate, Herman; Teng, Ping-Kun; Teoh, Jia Jian; Terada, Susumu; Terashi, Koji; Terron, Juan; Terzo, Stefano; Testa, Marianna; Teuscher, Richard; Therhaag, Jan; Theveneaux-Pelzer, Timothée; Thomas, Juergen; Thomas-Wilsker, Joshuha; Thompson, Emily; Thompson, Paul; Thompson, Peter; Thompson, Ray; Thompson, Stan; Thomsen, Lotte Ansgaard; Thomson, Evelyn; Thomson, Mark; Thong, Wai Meng; Thun, Rudolf; Tian, Feng; Tibbetts, Mark James; Tikhomirov, Vladimir; Tikhonov, Yury; Timoshenko, Sergey; Tiouchichine, Elodie; Tipton, Paul; Tisserant, Sylvain; Todorov, Theodore; Todorova-Nova, Sharka; Tojo, Junji; Tokár, Stanislav; Tokushuku, Katsuo; Tollefson, Kirsten; Tolley, Emma; Tomlinson, Lee; Tomoto, Makoto; Tompkins, Lauren; Toms, Konstantin; Topilin, Nikolai; Torrence, Eric; Torres, Heberth; Torró Pastor, Emma; Toth, Jozsef; Touchard, Francois; Tovey, Daniel; Tran, Huong Lan; Trefzger, Thomas; Tremblet, Louis; Tricoli, Alessandro; Trigger, Isabel Marian; Trincaz-Duvoid, Sophie; Tripiana, Martin; Trischuk, William; Trocmé, Benjamin; Troncon, Clara; Trottier-McDonald, Michel; Trovatelli, Monica; True, Patrick; Trzebinski, Maciej; Trzupek, Adam; Tsarouchas, Charilaos; Tseng, Jeffrey; Tsiareshka, Pavel; Tsionou, Dimitra; Tsipolitis, Georgios; Tsirintanis, Nikolaos; Tsiskaridze, Shota; Tsiskaridze, Vakhtang; Tskhadadze, Edisher; Tsukerman, Ilya; Tsulaia, Vakhtang; Tsuno, Soshi; Tsybychev, Dmitri; Tudorache, Alexandra; Tudorache, Valentina; Tuna, Alexander Naip; Tupputi, Salvatore; Turchikhin, Semen; Turecek, Daniel; Turk Cakir, Ilkay; Turra, Ruggero; Turvey, Andrew John; Tuts, Michael; Tykhonov, Andrii; Tylmad, Maja; Tyndel, Mike; Uchida, Kirika; Ueda, Ikuo; Ueno, Ryuichi; Ughetto, Michael; Ugland, Maren; Uhlenbrock, Mathias; Ukegawa, Fumihiko; Unal, Guillaume; Undrus, Alexander; Unel, Gokhan; Ungaro, Francesca; Unno, Yoshinobu; Unverdorben, Christopher; Urban, Jozef; Urbaniec, Dustin; Urquijo, Phillip; Usai, Giulio; Usanova, Anna; Vacavant, Laurent; Vacek, Vaclav; Vachon, Brigitte; Valencic, Nika; Valentinetti, Sara; Valero, Alberto; Valery, Loic; Valkar, Stefan; Valladolid Gallego, Eva; Vallecorsa, Sofia; Valls Ferrer, Juan Antonio; Van Den Wollenberg, Wouter; Van Der Deijl, Pieter; van der Geer, Rogier; van der Graaf, Harry; Van Der Leeuw, Robin; van der Ster, Daniel; van Eldik, Niels; van Gemmeren, Peter; Van Nieuwkoop, Jacobus; van Vulpen, Ivo; van Woerden, Marius Cornelis; Vanadia, Marco; Vandelli, Wainer; Vanguri, Rami; Vaniachine, Alexandre; Vankov, Peter; Vannucci, Francois; Vardanyan, Gagik; Vari, Riccardo; Varnes, Erich; Varol, Tulin; Varouchas, Dimitris; Vartapetian, Armen; Varvell, Kevin; Vazeille, Francois; Vazquez Schroeder, Tamara; Veatch, Jason; Veloso, Filipe; Velz, Thomas; Veneziano, Stefano; Ventura, Andrea; Ventura, Daniel; Venturi, Manuela; Venturi, Nicola; Venturini, Alessio; Vercesi, Valerio; Verducci, Monica; Verkerke, Wouter; Vermeulen, Jos; Vest, Anja; Vetterli, Michel; Viazlo, Oleksandr; Vichou, Irene; Vickey, Trevor; Vickey Boeriu, Oana Elena; Viehhauser, Georg; Viel, Simon; Vigne, Ralph; Villa, Mauro; Villaplana Perez, Miguel; Vilucchi, Elisabetta; Vincter, Manuella; Vinogradov, Vladimir; Virzi, Joseph; Vivarelli, Iacopo; Vives Vaque, Francesc; Vlachos, Sotirios; Vladoiu, Dan; Vlasak, Michal; Vogel, Adrian; Vogel, Marcelo; Vokac, Petr; Volpi, Guido; Volpi, Matteo; von der Schmitt, Hans; von Radziewski, Holger; von Toerne, Eckhard; Vorobel, Vit; Vorobev, Konstantin; Vos, Marcel; Voss, Rudiger; Vossebeld, Joost; Vranjes, Nenad; Vranjes Milosavljevic, Marija; Vrba, Vaclav; Vreeswijk, Marcel; Vu Anh, Tuan; Vuillermet, Raphael; Vukotic, Ilija; Vykydal, Zdenek; Wagner, Peter; Wagner, Wolfgang; Wahlberg, Hernan; Wahrmund, Sebastian; Wakabayashi, Jun; Walder, James; Walker, Rodney; Walkowiak, Wolfgang; Wall, Richard; Waller, Peter; Walsh, Brian; Wang, Chao; Wang, Chiho; Wang, Fuquan; Wang, Haichen; Wang, Hulin; Wang, Jike; Wang, Jin; Wang, Kuhan; Wang, Rui; Wang, Song-Ming; Wang, Tan; Wang, Xiaoxiao; Wanotayaroj, Chaowaroj; Warburton, Andreas; Ward, Patricia; Wardrope, David Robert; Warsinsky, Markus; Washbrook, Andrew; Wasicki, Christoph; Watkins, Peter; Watson, Alan; Watson, Ian; Watson, Miriam; Watts, Gordon; Watts, Stephen; Waugh, Ben; Webb, Samuel; Weber, Michele; Weber, Stefan Wolf; Webster, Jordan S; Weidberg, Anthony; Weinert, Benjamin; Weingarten, Jens; Weiser, Christian; Weits, Hartger; Wells, Phillippa; Wenaus, Torre; Wendland, Dennis; Weng, Zhili; Wengler, Thorsten; Wenig, Siegfried; Wermes, Norbert; Werner, Matthias; Werner, Per; Wessels, Martin; Wetter, Jeffrey; Whalen, Kathleen; White, Andrew; White, Martin; White, Ryan; White, Sebastian; Whiteson, Daniel; Wicke, Daniel; Wickens, Fred; Wiedenmann, Werner; Wielers, Monika; Wienemann, Peter; Wiglesworth, Craig; Wiik-Fuchs, Liv Antje Mari; Wijeratne, Peter Alexander; Wildauer, Andreas; Wildt, Martin Andre; Wilkens, Henric George; Williams, Hugh; Williams, Sarah; Willis, Christopher; Willocq, Stephane; Wilson, Alan; Wilson, John; Wingerter-Seez, Isabelle; Winklmeier, Frank; Winter, Benedict Tobias; Wittgen, Matthias; Wittig, Tobias; Wittkowski, Josephine; Wollstadt, Simon Jakob; Wolter, Marcin Wladyslaw; Wolters, Helmut; Wosiek, Barbara; Wotschack, Jorg; Woudstra, Martin; Wozniak, Krzysztof; Wright, Michael; Wu, Mengqing; Wu, Sau Lan; Wu, Xin; Wu, Yusheng; Wulf, Evan; Wyatt, Terry Richard; Wynne, Benjamin; Xella, Stefania; Xiao, Meng; Xu, Da; Xu, Lailin; Yabsley, Bruce; Yacoob, Sahal; Yakabe, Ryota; Yamada, Miho; Yamaguchi, Hiroshi; Yamaguchi, Yohei; Yamamoto, Akira; Yamamoto, Shimpei; Yamamura, Taiki; Yamanaka, Takashi; Yamauchi, Katsuya; Yamazaki, Yuji; Yan, Zhen; Yang, Haijun; Yang, Hongtao; Yang, Un-Ki; Yang, Yi; Yanush, Serguei; Yao, Liwen; Yao, Weiming; Yasu, Yoshiji; Yatsenko, Elena; Yau Wong, Kaven Henry; Ye, Jingbo; Ye, Shuwei; Yeletskikh, Ivan; Yen, Andy L; Yildirim, Eda; Yilmaz, Metin; Yoosoofmiya, Reza; Yorita, Kohei; Yoshida, Rikutaro; Yoshihara, Keisuke; Young, Charles; Young, Christopher John; Youssef, Saul; Yu, David Ren-Hwa; Yu, Jaehoon; Yu, Jiaming; Yu, Jie; Yuan, Li; Yurkewicz, Adam; Yusuff, Imran; Zabinski, Bartlomiej; Zaidan, Remi; Zaitsev, Alexander; Zaman, Aungshuman; Zambito, Stefano; Zanello, Lucia; Zanzi, Daniele; Zeitnitz, Christian; Zeman, Martin; Zemla, Andrzej; Zengel, Keith; Zenin, Oleg; Ženiš, Tibor; Zerwas, Dirk; Zevi della Porta, Giovanni; Zhang, Dongliang; Zhang, Fangzhou; Zhang, Huaqiao; Zhang, Jinlong; Zhang, Lei; Zhang, Ruiqi; Zhang, Xueyao; Zhang, Zhiqing; Zhao, Yongke; Zhao, Zhengguo; Zhemchugov, Alexey; Zhong, Jiahang; Zhou, Bing; Zhou, Lei; Zhou, Ning; Zhu, Cheng Guang; Zhu, Hongbo; Zhu, Junjie; Zhu, Yingchun; Zhuang, Xuai; Zhukov, Konstantin; Zibell, Andre; Zieminska, Daria; Zimine, Nikolai; Zimmermann, Christoph; Zimmermann, Robert; Zimmermann, Simone; Zimmermann, Stephanie; Zinonos, Zinonas; Ziolkowski, Michael; Zobernig, Georg; Zoccoli, Antonio; zur Nedden, Martin; Zurzolo, Giovanni; Zutshi, Vishnu; Zwalinski, Lukasz

    2014-11-19

    This Letter presents a search at the LHC for s-channel single top-quark production in proton-proton collisions at a centre-of-mass energy of 8 TeV. The analyzed data set was recorded by the ATLAS detector and corresponds to an integrated luminosity of 20.3 fb$^{-1}$. Selected events contain one charged lepton, large missing transverse momentum and exactly two b-tagged jets. A multivariate event classifier based on boosted decision trees is developed to discriminate s-channel single top-quark events from the main background contributions. The signal extraction is based on a binned maximum-likelihood fit of the output classifier distribution. The analysis leads to an upper limit on the s-channel single top-quark production cross-section of 14.6 pb at the 95% confidence level. The fit gives a cross-section of $\\sigma_s$=5.0$\\pm$4.3 pb, consistent with the Standard Model expectation.

  20. Current-Transport Mechanisms in the AlInN/AlN/GaN single-channel and AlInN/AlN/GaN/AlN/GaN double-channel heterostructures

    Energy Technology Data Exchange (ETDEWEB)

    Arslan, Engin, E-mail: engina@bilkent.edu.tr [Nanotechnology Research Center, Department of Physics, Department of Electrical and Electronics Engineering, Bilkent University, Bilkent, 06800 Ankara (Turkey); Turan, Sevil; Gökden, Sibel; Teke, Ali [Department of Physics, Faculty of Science and Letters, Balıkesir University, Çağış Kampüsü, 10145 Balıkesir (Turkey); Özbay, Ekmel [Nanotechnology Research Center, Department of Physics, Department of Electrical and Electronics Engineering, Bilkent University, Bilkent, 06800 Ankara (Turkey)

    2013-12-02

    Current-transport mechanisms were investigated in Schottky contacts on AlInN/AlN/GaN single channel (SC) and AlInN/AlN/GaN/AlN/GaN double channel (DC) heterostructures. A simple model was adapted to the current-transport mechanisms in DC heterostructure. In this model, two Schottky diodes are in series: one is a metal–semiconductor barrier layer (AIInN) Schottky diode and the other is an equivalent Schottky diode, which is due to the heterojunction between the AlN and GaN layer. Capacitance–voltage studies show the formation of a two-dimensional electron gas at the AlN/GaN interface in the SC and the first AlN/GaN interface from the substrate direction in the DC. In order to determine the current mechanisms for SC and DC heterostructures, we fit the analytical expressions given for the tunneling current to the experimental current–voltage data over a wide range of applied biases as well as at different temperatures. We observed a weak temperature dependence of the saturation current and a fairly small dependence on the temperature of the tunneling parameters in this temperature range. At both a low and medium forward-bias voltage values for Schottky contacts on AlInN/AlN/GaN/AlN/GaN DC and AlInN/AlN/GaN SC heterostructures, the data are consistent with electron tunneling to deep levels in the vicinity of mixed/screw dislocations in the temperature range of 80–420 K. - Highlights: • Current mechanisms were investigated on single and double channel heterostructures. • A model was adapted to the current mechanisms in double channel heterostructures. • We observed a weak temperature dependence of the saturation current. • And a small dependence of the tunneling parameters in this temperature range.

  1. Current-Transport Mechanisms in the AlInN/AlN/GaN single-channel and AlInN/AlN/GaN/AlN/GaN double-channel heterostructures

    International Nuclear Information System (INIS)

    Arslan, Engin; Turan, Sevil; Gökden, Sibel; Teke, Ali; Özbay, Ekmel

    2013-01-01

    Current-transport mechanisms were investigated in Schottky contacts on AlInN/AlN/GaN single channel (SC) and AlInN/AlN/GaN/AlN/GaN double channel (DC) heterostructures. A simple model was adapted to the current-transport mechanisms in DC heterostructure. In this model, two Schottky diodes are in series: one is a metal–semiconductor barrier layer (AIInN) Schottky diode and the other is an equivalent Schottky diode, which is due to the heterojunction between the AlN and GaN layer. Capacitance–voltage studies show the formation of a two-dimensional electron gas at the AlN/GaN interface in the SC and the first AlN/GaN interface from the substrate direction in the DC. In order to determine the current mechanisms for SC and DC heterostructures, we fit the analytical expressions given for the tunneling current to the experimental current–voltage data over a wide range of applied biases as well as at different temperatures. We observed a weak temperature dependence of the saturation current and a fairly small dependence on the temperature of the tunneling parameters in this temperature range. At both a low and medium forward-bias voltage values for Schottky contacts on AlInN/AlN/GaN/AlN/GaN DC and AlInN/AlN/GaN SC heterostructures, the data are consistent with electron tunneling to deep levels in the vicinity of mixed/screw dislocations in the temperature range of 80–420 K. - Highlights: • Current mechanisms were investigated on single and double channel heterostructures. • A model was adapted to the current mechanisms in double channel heterostructures. • We observed a weak temperature dependence of the saturation current. • And a small dependence of the tunneling parameters in this temperature range

  2. Influence of gold coating and interplate voltage on the performance of chevron micro-channel plates for temporally and spatially resolved single particle detection

    Science.gov (United States)

    Hoendervanger, A. L.; Clément, D.; Aspect, A.; Westbrook, C. I.; Dowek, D.; Picard, Y. J.; Boiron, D.

    2013-02-01

    We present a study of two different sets of Micro-Channel Plates used for time and space resolved single particle detection. We investigate the effects of the gold coating and that of introducing an interplate voltage between the spatially separated plates. We find that the gold coating increases the count rate of the detector and the pulse amplitude as previously reported for non-spatially resolved setups. The interplate voltage also increases count rates. In addition, we find that a non-zero interplate voltage improves the spatial accuracy in determining the arrival position of incoming single particles (by ˜20%) while the gold coating has a negative effect (by ˜30%).

  3. Single-channel L-type Ca2+ currents in chicken embryo semicircular canal type I and type II hair cells.

    Science.gov (United States)

    Zampini, Valeria; Valli, Paolo; Zucca, Giampiero; Masetto, Sergio

    2006-08-01

    Few data are available concerning single Ca channel properties in inner ear hair cells and particularly none in vestibular type I hair cells. By using the cell-attached configuration of the patch-clamp technique in combination with the semicircular canal crista slice preparation, we determined the elementary properties of voltage-dependent Ca channels in chicken embryo type I and type II hair cells. The pipette solutions included Bay K 8644. With 70 mM Ba(2+) in the patch pipette, Ca channel activity appeared as very brief openings at -60 mV. Ca channel properties were found to be similar in type I and type II hair cells; therefore data were pooled. The mean inward current amplitude was -1.3 +/- 0.1 (SD) pA at - 30 mV (n = 16). The average slope conductance was 21 pS (n = 20). With 5 mM Ba(2+) in the patch pipette, very brief openings were already detectable at -80 mV. The mean inward current amplitude was -0.7 +/- 0.2 pA at -40 mV (n = 9). The average slope conductance was 11 pS (n = 9). The mean open time and the open probability increased significantly with depolarization. Ca channel activity was still present and unaffected when omega-agatoxin IVA (2 microM) and omega-conotoxin GVIA (3.2 microM) were added to the pipette solution. Our results show that types I and II hair cells express L-type Ca channels with similar properties. Moreover, they suggest that in vivo Ca(2+) influx might occur at membrane voltages more negative than -60 mV.

  4. Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels.

    Science.gov (United States)

    Glasscock, Edward; Qian, Jing; Kole, Matthew J; Noebels, Jeffrey L

    2012-08-15

    Kv1.1 channels cluster at juxtaparanodes of myelinated axons in the vagus nerve, the primary conduit for parasympathetic innervation of the heart. Kcna1-null mice lacking these channels exhibit neurocardiac dysfunction manifested by atropine-sensitive atrioventricular conduction blocks and bradycardia that may culminate in sudden death. To evaluate whether loss of Kv1.1 channels alters electrogenic properties within the nerve, we compared the intrinsic excitability of single myelinated A- and Aδ-axons from excised cervical vagus nerves of young adult Kcna1-null mice and age-matched, wild-type littermate controls. Although action potential shapes and relative refractory periods varied little between genotypes, Kv1.1-deficient large myelinated A-axons showed a fivefold increase in susceptibility to 4-aminopyridine (4-AP)-induced spontaneous ectopic firing. Since the repolarizing currents of juxtaparanodal Kv1 channels and nodal KCNQ potassium channels both act to dampen repetitive activity, we examined whether augmenting nodal KCNQ activation could compensate for Kv1.1 loss and reverse the spontaneous hyperexcitability in Kv1.1-deficient A-axons. Application of the selective KCNQ opener flupirtine raised A-axon firing threshold while profoundly suppressing 4-AP-induced spontaneous firing, demonstrating a functional synergy between the two compartments. We conclude that juxtaparanodal Kv1.1-deficiency causes intrinsic hyperexcitability in large myelinated axons in vagus nerve which could contribute to autonomic dysfunction in Kcna1-null mice, and that KCNQ openers reveal a transcompartmental synergy between Kv1 and KCNQ channels in regulating axonal excitability.

  5. Submerged and buried Pleistocene river channels in the Gulf of Trieste (Northern Adriatic Sea): Geomorphic, stratigraphic and tectonic inferences

    Science.gov (United States)

    Trobec, Ana; Šmuc, Andrej; Poglajen, Sašo; Vrabec, Marko

    2017-06-01

    We use multibeam sonar scanning of the seafloor and high-resolution sub-bottom sonar profiling to investigate pre-Holocene geomorphic features in the Gulf of Trieste that are visible in seafloor topography. We focus on two channel-like features, the Paleorižana and Paleoreka. Sub-bottom profiles and published core log data reveal that these features represent the transgressive surface at the boundary between Pleistocene continental and Holocene marine sedimentation. The geometry of the paleosurface, the architecture, and the acoustic facies of underlying sediment bodies clearly show that this surface represents an alluvial plain containing a moderate- to low-energy floodplain. The Paleorižana feature represents a meander belt with multiple meander scars and oxbow lakes, while the Paleoreka is a single, slightly sinuous channel river with well-developed levees. Geomorphic characteristics of the two rivers are replicated in the seafloor topography in astonishing detail, despite being draped by up to 10 m of Holocene marine sediments. We extract Paleoreka thalweg depths from sub-bottom profiles to construct a longitudinal channel profile, which runs approximately perpendicular to the main tectonic structures of the Gulf. We find no evidence of long-term mm-scale localized relative vertical tectonic movements which were previously inferred from repeated geodetic levelling surveys along the SW-NE oriented Slovenian coastline. We speculate that the geodetic data may instead indicate short-term interseismic deformation along the Slovenian coast, which would necessitate further investigation of tectonic activity and seismic hazard in the Gulf area.

  6. A new architecture for a single-chip multi-channel beamformer based on a standard FPGA

    DEFF Research Database (Denmark)

    Tomov, Borislav Gueorguiev; Jensen, Jørgen Arendt

    2001-01-01

    A new architecture for a compact medical ultrasound beamformer has been developed. Combination of novel and known principles has been utilized, leading to low processing power requirements and simple analog circuitry. Usage of a field programmable gate array (FPGA) for the digital signal processing...... provides programming flexibility. First, sparse sample processing is performed by generating the in-phase and quadrature beamformed signals. Hereby only 512 samples are beamformed for each line in an image. That leads to a 15-fold decrease in the number of operations and enables the use of Delta-Sigma (ΔΣ....... The control logic consists of few adders and counters and requires very limited resources. Fourth, the beamformer is fully programmable. Any channel can be set to use an arbitrary delay curve, and any number of these channels can be used together in an extendable modular multi-channel system. A prototype...

  7. The incidence of the different sources of noise on the uncertainty in radiochromic film dosimetry using single channel and multichannel methods

    Science.gov (United States)

    González-López, Antonio; Vera-Sánchez, Juan Antonio; Ruiz-Morales, Carmen

    2017-11-01

    The influence of the various sources of noise on the uncertainty in radiochromic film (RCF) dosimetry using single channel and multichannel methods is investigated in this work. These sources of noise are extracted from pixel value (PV) readings and dose maps. Pieces of an RCF were each irradiated to different uniform doses, ranging from 0 to 1092 cGy. Then, the pieces were read at two resolutions (72 and 150 ppp) with two flatbed scanners: Epson 10000XL and Epson V800, representing two states of technology. Noise was extracted as described in ISO 15739 (2013), separating its distinct constituents: random noise and fixed pattern (FP) noise. Regarding the PV maps, FP noise is the main source of noise for both models of digitizer. Also, the standard deviation of the random noise in the 10000XL model is almost twice that of the V800 model. In the dose maps, the FP noise is smaller in the multichannel method than in the single channel ones. However, random noise is higher in this method, throughout the dose range. In the multichannel method, FP noise is reduced, as a consequence of this method’s ability to eliminate channel independent perturbations. However, the random noise increases, because the dose is calculated as a linear combination of the doses obtained by the single channel methods. The values of the coefficients of this linear combination are obtained in the present study, and the root of the sum of their squares is shown to range between 0.9 and 1.9 over the dose range studied. These results indicate the random noise to play a fundamental role in the uncertainty of RCF dosimetry: low levels of random noise are required in the digitizer to fully exploit the advantages of the multichannel dosimetry method. This is particularly important for measuring high doses at high spatial resolutions.

  8. First demonstration of single-mode MCF transport network with crosstalk-aware in-service optical channel control

    DEFF Research Database (Denmark)

    Pulverer, K.; Tanaka, T.; Häbel, U.

    2017-01-01

    We demonstrate the first crosstalk-aware traffic engineering as a use case in a multicore fibre transport network. With the help of a software-defined network controller, modulation format and channel route are adaptively changed using programmable devices with XT monitors.......We demonstrate the first crosstalk-aware traffic engineering as a use case in a multicore fibre transport network. With the help of a software-defined network controller, modulation format and channel route are adaptively changed using programmable devices with XT monitors....

  9. Structural properties of as-grown and reduced Pr2CuO4 single crystals investigated by ion channeling

    International Nuclear Information System (INIS)

    Haga, T.; Abe, Y.

    1996-01-01

    Ion channeling is very sensitive to atomic arrangements and small atomic displacements in real space. Thus, in order to clarify a role of reduction for Pr 2 CuO 4 , ion channeling properties for the materials have been measured in detail. Anomalous increases of dechanneling fractions of Cu and O atoms in the reduced samples have been found. These results could not be explained by the apical oxygen model but probably suggest that O atoms in Cu-O planes are removed by reduction. Taking these results into account, correlation between lattice instability and superconductivity in the material will be discussed. (orig.)

  10. Measurement of the inclusive cross section of single top quark production in the $t$ channel at $\\sqrt{s} = 13\\,\\mathrm{TeV}$

    CERN Document Server

    CMS Collaboration

    2016-01-01

    The $t$ channel single top quark production cross section is measured in proton proton collisions at $13\\,\\mathrm{TeV}$ with the CMS detector at the CERN LHC. The analyzed data correspond to an integrated luminosity of $2.3\\,\\mathrm{fb}^{-1}$. After a selection optimized for the $t$ channel single top quark production with a muon+jets signature in the final state, several kinematic variables are combined into one multivariate discriminator optimized to separate signal from background events. A fit to the distribution of the discriminating variable yields cross sections of $\\sigma_{t\\textrm{-ch.,t}} = 141.5 \\pm 6.7\\,{\\rm(stat.)} \\pm 9.4\\,{\\rm(exp.)}\\,^{+19.3}_{-19.6}\\,{\\rm(theo.)}\\pm 3.8\\,{\\rm(lumi.)}\\,{\\rm pb}$ and $\\sigma_{t\\textrm{-ch.,}\\bar{\\textrm{t}}} = 81.0 \\pm 6.2\\,{\\rm(stat.)} \\pm 8.1\\,{\\rm(exp.)}\\,^{+10.9}_{-10.9}\\,{\\rm(theo.)}\\pm 2.2\\,{\\rm(lumi.)}\\,{\\rm pb}$ for the production of single top quarks and single top anti-quarks, respectively. From the measured inclusive cross section, $\\sigma_{t\\textrm{...

  11. A Unified Algorithm for Channel Imbalance and Antenna Phase Center Position Calibration of a Single-Pass Multi-Baseline TomoSAR System

    Directory of Open Access Journals (Sweden)

    Yuncheng Bu

    2018-03-01

    Full Text Available The multi-baseline synthetic aperture radar (SAR tomography (TomoSAR system is employed in such applications as disaster remote sensing, urban 3-D reconstruction, and forest carbon storage estimation. This is because of its 3-D imaging capability in a single-pass platform. However, a high 3-D resolution of TomoSAR is based on the premise that the channel imbalance and antenna phase center (APC position are precisely known. If this is not the case, the 3-D resolution performance will be seriously degraded. In this paper, a unified algorithm for channel imbalance and APC position calibration of a single-pass multi-baseline TomoSAR system is proposed. Based on the maximum likelihood method, as well as the least squares and the damped Newton method, we can calibrate the channel imbalance and APC position. The algorithm is suitable for near-field conditions, and no phase unwrapping operation is required. The effectiveness of the proposed algorithm has been verified by simulation and experimental results.

  12. First demonstration of single-mode MCF transport network with crosstalk-aware in-service optical channel control

    DEFF Research Database (Denmark)

    Pulverer, K.; Tanaka, T.; Häbel, U.

    2017-01-01

    We demonstrate the first crosstalk-aware traffic engineering as a use case in a multicore fibre transport network. With the help of a software-defined network controller, modulation format and channel route are adaptively changed using programmable devices with XT monitors....

  13. Discharge estimation in a backwater affected meandering river

    NARCIS (Netherlands)

    Hidayat, H.; Vermeulen, B.; Sassi, M.G.; Torfs, P.J.J.F.; Hoitink, A.J.F.

    2011-01-01

    Variable effects of backwaters complicate the development of rating curves at hydrometric measurement stations. In areas influenced by backwater, single-parameter rating curve techniques are often inapplicable. To overcome this, several authors have advocated the use of an additional downstream

  14. Development of an analytical Lagrangian model for passive scalar dispersion in low-wind speed meandering conditions

    Science.gov (United States)

    Stefanello, M. B.; Degrazia, G. A.; Mortarini, L.; Buligon, L.; Maldaner, S.; Carvalho, J. C.; Acevedo, O. C.; Martins, L. G. N.; Anfossi, D.; Buriol, C.; Roberti, D.

    2018-02-01

    Describing the effects of wind meandering motions on the dispersion of scalars is a challenging task, since this type of flow represents a physical state characterized by multiple scales. In this study, a Lagrangian stochastic diffusion model is derived to describe scalar transport during the horizontal wind meandering phenomenon that occurs within a planetary boundary layer. The model is derived from the linearization of the Langevin equation, and it employs a heuristic functional form that represents the autocorrelation function of meandering motion. The new solutions, which describe the longitudinal and lateral wind components, were used to simulate tracer experiments that were performed in low-wind speed conditions. The results of the comparison indicate that the new model can effectively reproduce the observed concentrations of the contaminants, and therefore, it can satisfactorily describe enhanced dispersion effects due to the presence of meandering.

  15. Maximum outer-bank velocity reduction for vane-dike fields installed in channel bends

    Science.gov (United States)

    S. Michael Scurlock; Amanda L. Cox; Christopher I. Thornton; Drew C. Baird

    2011-01-01

    Hydraulic conditions associated with channel bends in meandering rivers include secondary, helical currents, mass shift of flow to the outside of the bend, and increased erosion along the outer streambank. Such outer-bank erosion may result in undesired plan-form migration of the stream course, placing valuable land holdings or infrastructure in jeopardy. A type of in-...

  16. Magnetic fingerprint of the sediment load in a meander bend section of the Seine River (France)

    Science.gov (United States)

    Kayvantash, D.; Cojan, I.; Kissel, C.; Franke, C.

    2017-06-01

    This study aims to evaluate the potential of magnetic methods to determine the composition of the sediment load in a cross section of an unmanaged meander in the upstream stretch of the Seine River (Marnay-sur-Seine). Suspended particulate matter (SPM) was collected based on a regular sampling scheme along a cross section of the river, at two different depth levels: during a low-water stage (May 2014) and a high-water stage (February 2015). Riverbed sediments (RBS) were collected during the low-water stage and supplementary samples were taken from the outer and inner banks. Magnetic properties of the dry bulk SPM and sieved RBS and bank sediments were analysed. After characterizing the main magnetic carrier as magnetite, hysteresis parameters were measured, giving access to the grain size and the concentration of these magnetite particles. The results combined with sedimentary grain size data were compared to the three-dimensional velocity profile of the river flow. In the RBS where the magnetic grain size is rather uniform, the concentration of magnetite is inversely proportional to the mean grain size of the total sediment indicating that magnetite is strongly associated with the fine sedimentary fraction. The same pattern is observed in the samples from the outer and inner banks. During the low-water stage, the uniformly fine SPM grain size distribution characterizes the wash load. The magnetic fraction is also relatively fine (within the pseudo single domain range) with concentration similar to that of the fine RBS fraction. During the high-water stage, SPM samples correspond to mixtures of wash load and resuspended sediment from the bedload and riverbanks. Here, the grain size distribution is heterogeneous across the section showing coarser particles compared to those in the low-water stage and more varying magnetite concentrations while the magnetic grain size is like that of the low-water stage. The magnetite concentration in the high-water SPM can be

  17. Stratigraphy and paleohydrology of delta channel deposits, Jezero crater, Mars

    Science.gov (United States)

    Goudge, Timothy A.; Mohrig, David; Cardenas, Benjamin T.; Hughes, Cory M.; Fassett, Caleb I.

    2018-02-01

    The Jezero crater open-basin lake contains two well-exposed fluvial sedimentary deposits formed early in martian history. Here, we examine the geometry and architecture of the Jezero western delta fluvial stratigraphy using high-resolution orbital images and digital elevation models (DEMs). The goal of this analysis is to reconstruct the evolution of the delta and associated shoreline position. The delta outcrop contains three distinct classes of fluvial stratigraphy that we interpret, from oldest to youngest, as: (1) point bar strata deposited by repeated flood events in meandering channels; (2) inverted channel-filling deposits formed by avulsive distributary channels; and (3) a valley that incises the deposit. We use DEMs to quantify the geometry of the channel deposits and estimate flow depths of ∼7 m for the meandering channels and ∼2 m for the avulsive distributary channels. Using these estimates, we employ a novel approach for assessing paleohydrology of the formative channels in relative terms. This analysis indicates that the shift from meandering to avulsive distributary channels was associated with an approximately four-fold decrease in the water to sediment discharge ratio. We use observations of the fluvial stratigraphy and channel paleohydrology to propose a model for the evolution of the Jezero western delta. The delta stratigraphy records lake level rise and shoreline transgression associated with approximately continuous filling of the basin, followed by outlet breaching, and eventual erosion of the delta. Our results imply a martian surface environment during the period of delta formation that supplied sufficient surface runoff to fill the Jezero basin without major drops in lake level, but also with discrete flooding events at non-orbital (e.g., annual to decadal) timescales.

  18. Microscopic mechanisms for long QT syndrome type 1 revealed by single-channel analysis of I(Ks) with S3 domain mutations in KCNQ1.

    Science.gov (United States)

    Eldstrom, Jodene; Wang, Zhuren; Werry, Daniel; Wong, Nathan; Fedida, David

    2015-02-01

    The slowly activating delayed rectifier current IKs participates in cardiac repolarization, particularly at high heart rates, and mutations in this K(+) channel complex underlie long QT syndrome (LQTS) types 1 and 5. The purpose of this study was to determine biophysical mechanisms of LQT1 through single-channel kinetic analysis of IKs carrying LQT1 mutations in the S3 transmembrane region of the pore-forming subunit KCNQ1. We analyzed cell-attached recordings from mammalian cells in which a single active KCNQ1 (wild type or mutant) and KCNE1 complex could be detected. The S3 mutants of KCNQ1 studied (D202H, I204F, V205M, and S209F), with the exception of S209F, all led to a reduction in channel activity through distinct kinetic mechanisms. D202H, I204F, and V205M showed decreased open probability (Po) compared with wild type (0.07, 0.04, and 0.12 vs 0.2); increased first latency from 1.66 to >2 seconds at +60 mV (I204F, V205M); variable-to-severe reductions in open dwell times (≥50% in V205M); stabilization of closed states (D202H); and an inability of channels to reach full conductance levels (V205M, I204F). S209F is a kinetic gain-of-function mutation with a high Po (0.40) and long open-state dwell times. S3 mutations in KCNQ1 cause diverse kinetic defects in I(Ks), affecting opening and closing properties, and can account for LQT1 phenotypes. Copyright © 2015 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  19. Calibration and Validation of the Dynamic Wake Meandering Model for Implementation in an Aeroelastic Code

    DEFF Research Database (Denmark)

    Aagaard Madsen, Helge; Larsen, Gunner Chr.; Larsen, Torben J.

    2010-01-01

    in an aeroelastic model. Calibration and validation of the different parts of the model is carried out by comparisons with actuator disk and actuator line (ACL) computations as well as with inflow measurements on a full-scale 2 MW turbine. It is shown that the load generating part of the increased turbulence......As the major part of new wind turbines are installed in clusters or wind farms, there is a strong need for reliable and accurate tools for predicting the increased loadings due to wake operation and the associated reduced power production. The dynamic wake meandering (DWM) model has been developed...... on this background, and the basic physical mechanisms in the wake—i.e., the velocity deficit, the meandering of the deficit, and the added turbulence—are modeled as simply as possible in order to make fast computations. In the present paper, the DWM model is presented in a version suitable for full integration...

  20. A consistent turbulence formulation for the dynamic wake meandering model in the atmospheric boundary layer

    DEFF Research Database (Denmark)

    Keck, Rolf-Erik; Veldkamp, Dick; Wedel-Heinen, Jens Jakob

    as a standalone flow-solver for the velocity and turbulence distribution, and power production in a wind farm. The performance of the standalone implementation is validated against field data, higher-order computational fluid dynamics models, as well as the most common engineering wake models in the wind industry...... evolution 4. atmospheric stability effects on wake deficit evolution and meandering The conducted research is to a large extent based on detailed wake investigations and reference data generated through computational fluid dynamics simulations, where the wind turbine rotor has been represented......This thesis describes the further development and validation of the dynamic meandering wake model for simulating the flow field and power production of wind farms operating in the atmospheric boundary layer (ABL). The overall objective of the conducted research is to improve the modelling...

  1. Dielectric-based subwavelength metallic meanders for wide-angle band absorbers.

    Science.gov (United States)

    Shen, Su; Qiao, Wen; Ye, Yan; Zhou, Yun; Chen, Linsen

    2015-01-26

    We propose nano-meanders that can achieve wide-angle band absorption in visible regime. The nano-meander consists of a subwavelength dielectric grating covered by continuous ultra-thin Aluminum film (less than one tenth of the incident wavelength). The excited photonic resonant modes, such as cavity mode, surface plasmonic mode and Rayleigh-Wood anomaly, are discussed in detail. Nearly total resonant absorption due to funneling mechanism in the air nano-groove is almost invariant with large incident angle in transverse magnetic polarization. From both the structural geometry and the nanofabrication point of view, the light absorber has a very simple geometrical structure and it is easy to be integrated into complex photonic devices. The highly efficient angle-robust light absorber can be potential candidate for a range of passive and active photonic applications, including solar-energy harvesting as well as producing artificial colors on a large scale substrate.

  2. On the relevance of diapycnal mixing for the stability of frontal meanders

    Directory of Open Access Journals (Sweden)

    A. Rodríguez-Santana

    2001-07-01

    Full Text Available This work examines the possible importance of shear-induced diapycnal mixing in controlling the evolution and stability of meanders in oceanic frontal jets. We first review the conditions necessary for vortex stability and investigate how these may be modified in the presence of diapycnal mixing. The procedure used is rather crude but provides a measure of the relative importance of diapycnal mixing. It consists in constructing a simplified equation for the radial velocity that retains the density tendency and examining under what circumstances this velocity may grow in time. Next, we use a simple two-dimensional isopycnic model to examine the intensity of diapycnal mixing in meanders. In the model the along-front velocity is in geostrophic balance and the ageostrophic contributions are an oscillating deformation field and diapycnal mass exchange. The horizontal deformation field increases the slope of the isopycnals in temporal scales typical of Gulf Stream meanders, causing a reduction of the gradient Richardson number, Ri. The diapycnal flux is calculated as the divergence of the density Reynolds flux, which is parameterized in terms of Ri. The results of the model show that diapycnal mixing increases during the frontogenetical stages, reaching density tendency values of the order of 10-4 kg m-3s-1 and convergence/divergence values of the order of 10-3 s-1. It turns out that diapycnal mixing in meanders may be intense enough to control the separation and slope of the isopycnals and to condition the possibility of barotropic instability.

  3. Measurement of the inclusive cross-section of single top-quark $t$-channel production in $pp$ collisions at $\\sqrt{s}$ = 13 TeV

    CERN Document Server

    The ATLAS collaboration

    2015-01-01

    A measurement of the $t$-channel single top-quark production cross-section in the lepton+jets channel using 3.2 fb$^{-1}$ $pp$ collision data at a centre-of-mass energy of 13 TeV, recorded with the ATLAS detector in 2015, is presented. Events are selected by requiring one muon, missing transverse momentum, and two high-$p_{\\mathrm T}$ jets, one of which is required to be $b$-tagged. Using a binned maximum-likelihood fit to the output distribution of a neural network, the cross-sections are determined to be $\\sigma(tq) = 133 \\pm 6 \\, (\\mathrm{stat.}) \\pm 24 \\, (\\mathrm{syst.}) \\pm 7 \\,(\\mathrm{lumi.})~\\text{pb}$ for single top-quark production and $\\sigma(\\bar{t} q) = 96 \\pm 5 \\, (\\mathrm{stat.}) \\pm 23 \\, (\\mathrm{syst.}) \\pm 5\\,(\\mathrm{lumi.})~\\text{pb}$ for single top-antiquark production, assuming a top-quark mass of 172.5 GeV. Using the predicted value of $\\sigma(tq)$ at next-to-leading order and assuming that the top-quark-related CKM matrix elements obey the relation $|V_{tb}|\\gg |V_{ts}|, |V_{td}|$, t...

  4. Effect of the speed of a single-channel dynamic range compressor on intelligibility in a competing speech task

    Science.gov (United States)

    Stone, Michael A.; Moore, Brian C. J.

    2003-08-01

    Using a ``noise-vocoder'' cochlear implant simulator [Shannon et al., Science 270, 303-304 (1995)], the effect of the speed of dynamic range compression on speech intelligibility was assessed, using normal-hearing subjects. The target speech had a level 5 dB above that of the competing speech. Initially, baseline performance was measured with no compression active, using between 4 and 16 processing channels. Then, performance was measured using a fast-acting compressor and a slow-acting compressor, each operating prior to the vocoder simulation. The fast system produced significant gain variation over syllabic timescales. The slow system produced significant gain variation only over the timescale of sentences. With no compression active, about six channels were necessary to achieve 50% correct identification of words in sentences. Sixteen channels produced near-maximum performance. Slow-acting compression produced no significant degradation relative to the baseline. However, fast-acting compression consistently reduced performance relative to that for the baseline, over a wide range of performance levels. It is suggested that fast-acting compression degrades performance for two reasons: (1) because it introduces correlated fluctuations in amplitude in different frequency bands, which tends to produce perceptual fusion of the target and background sounds and (2) because it reduces amplitude modulation depth and intensity contrasts.

  5. Cardiac imaging at 7 Tesla: Single- and two-spoke radiofrequency pulse design with 16-channel parallel excitation.

    Science.gov (United States)

    Schmitter, Sebastian; DelaBarre, Lance; Wu, Xiaoping; Greiser, Andreas; Wang, Dingxin; Auerbach, Edward J; Vaughan, J Thomas; Uğurbil, Kâmil; Van de Moortele, Pierre-François

    2013-11-01

    Higher signal to noise ratio (SNR) and improved contrast have been demonstrated at ultra-high magnetic fields (≥7 Tesla [T]) in multiple targets, often with multi-channel transmit methods to address the deleterious impact on tissue contrast due to spatial variations in B1 (+) profiles. When imaging the heart at 7T, however, respiratory and cardiac motion, as well as B0 inhomogeneity, greatly increase the methodological challenge. In this study we compare two-spoke parallel transmit (pTX) RF pulses with static B1 (+) shimming in cardiac imaging at 7T. Using a 16-channel pTX system, slice-selective two-spoke pTX pulses and static B1 (+) shimming were applied in cardiac CINE imaging. B1 (+) and B0 mapping required modified cardiac triggered sequences. Excitation homogeneity and RF energy were compared in different imaging orientations. Two-spoke pulses provide higher excitation homogeneity than B1 (+) shimming, especially in the more challenging posterior region of the heart. The peak value of channel-wise RF energy was reduced, allowing for a higher flip angle, hence increased tissue contrast. Image quality with two-spoke excitation proved to be stable throughout the entire cardiac cycle. Two-spoke pTX excitation has been successfully demonstrated in the human heart at 7T, with improved image quality and reduced RF pulse energy when compared with B1 (+) shimming. Copyright © 2013 Wiley Periodicals, Inc.

  6. Characterization and modeling of a new magnetorheological damper with meandering type valve using neuro-fuzzy

    Directory of Open Access Journals (Sweden)

    Fitrian Imaduddin

    2017-10-01

    Full Text Available This paper presents the characterization and hysteresis modeling of magnetorheological (MR damper with meandering type valve. The meandering type MR valve, which employs the combination of multiple annular and radial flow passages, has been introduced as the new type of high performance MR valve with higher achievable pressure drop and controllable performance range than similar counterparts in its class. Since the performance of a damper is highly determined by the valve performance, the utilization of the meandering type MR valve in an MR damper could potentially improve the damper performance. The damping force characterization of the MR damper is conducted by measuring the damping force as a response to the variety of harmonic excitations. The hysteresis behavior of the damper is identified by plotting the damping force relationship to the excitation displacement and velocity. For the hysteresis modeling purpose, some parts of the data are taken as the training data source for the optimization parameters in the neuro-fuzzy model. The performance of the trained neuro-fuzzy model is assessed by validating the model output with the remaining measurement data and benchmarking the results with the output of the parametric hysteresis model. The validation results show that the neuro-fuzzy model is demonstrating good agreement with the measurement results indicated by the average relative error of only around 7%. The model also shows robustness with no tendency of growing error when the input values are changed.

  7. Monitoring driver fatigue using a single-channel electroencephalographic device: A validation study by gaze-based, driving performance, and subjective data.

    Science.gov (United States)

    Morales, José M; Díaz-Piedra, Carolina; Rieiro, Héctor; Roca-González, Joaquín; Romero, Samuel; Catena, Andrés; Fuentes, Luis J; Di Stasi, Leandro L

    2017-12-01

    Driver fatigue can impair performance as much as alcohol does. It is the most important road safety concern, causing thousands of accidents and fatalities every year. Thanks to technological developments, wearable, single-channel EEG devices are now getting considerable attention as fatigue monitors, as they could help drivers to assess their own levels of fatigue and, therefore, prevent the deterioration of performance. However, the few studies that have used single-channel EEG devices to investigate the physiological effects of driver fatigue have had inconsistent results, and the question of whether we can monitor driver fatigue reliably with these EEG devices remains open. Here, we assessed the validity of a single-channel EEG device (TGAM-based chip) to monitor changes in mental state (from alertness to fatigue). Fifteen drivers performed a 2-h simulated driving task while we recorded, simultaneously, their prefrontal brain activity and saccadic velocity. We used saccadic velocity as the reference index of fatigue. We also collected subjective ratings of alertness and fatigue, as well as driving performance. We found that the power spectra of the delta EEG band showed an inverted U-shaped quadratic trend (EEG power spectra increased for the first hour and half, and decreased during the last thirty minutes), while the power spectra of the beta band linearly increased as the driving session progressed. Coherently, saccadic velocity linearly decreased and speeding time increased, suggesting a clear effect of fatigue. Subjective data corroborated these conclusions. Overall, our results suggest that the TGAM-based chip EEG device is able to detect changes in mental state while performing a complex and dynamic everyday task as driving. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Cross section measurement of $t$-channel single top quark production in pp collisions at $\\sqrt{s}$ = 13 TeV

    CERN Document Server

    INSPIRE-00529670

    2017-01-01

    The electroweak production of single-top quarks in the t-channel can be changed by any deviation from the Standard Model, it is therefore an excellent opportunity to search for new physics. In this poster the recent cross-section measurement of the CMS collaboration is presented with the full 2015 dataset of the LHC Run II at a center-of-mass energy of 13 TeV. The cross section and the top/antitop ratio is extracted using a binned maximum likelihood fit to the distribution of a multivariate classifier in events containing one isolated muon in the final state.

  9. Fluoride export (FEX proteins from fungi, plants and animals are 'single barreled' channels containing one functional and one vestigial ion pore.

    Directory of Open Access Journals (Sweden)

    Tetyana Berbasova

    Full Text Available The fluoride export protein (FEX in yeast and other fungi provides tolerance to fluoride (F-, an environmentally ubiquitous anion. FEX efficiently eliminates intracellular fluoride that otherwise would accumulate at toxic concentrations. The FEX homolog in bacteria, Fluc, is a 'double-barreled' channel formed by dimerization of two identical or similar subunits. FEX in yeast and other eukaryotes is a monomer resulting from covalent fusion of the two subunits. As a result, both potential fluoride pores are created from different parts of the same protein. Here we identify FEX proteins from two multicellular eukaryotes, a plant Arabidopsis thaliana and an animal Amphimedon queenslandica, by demonstrating significant fluoride tolerance when these proteins are heterologously expressed in the yeast Saccharomyces cerevisiae. Residues important for eukaryotic FEX function were determined by phylogenetic sequence alignment and functional analysis using a yeast growth assay. Key residues of the fluoride channel are conserved in only one of the two potential fluoride-transporting pores. FEX activity is abolished upon mutation of residues in this conserved pore, suggesting that only one of the pores is functional. The same topology is conserved for the newly identified FEX proteins from plant and animal. These data suggest that FEX family of fluoride channels in eukaryotes are 'single-barreled' transporters containing one functional pore and a second non-functional vestigial remnant of a homologous gene fusion event.

  10. Channel capacity of TDD-OFDM-MIMO for multiple access points in a wireless single-frequency-network

    DEFF Research Database (Denmark)

    Takatori, Y.; Fitzek, Frank; Tsunekawa, K.

    2005-01-01

    The multiple-input-multiple-output (MIMO) technique is the most attractive candidate to improve the spectrum efficiency in the next generation wireless communication systems. However, the efficiency of MIMO techniques reduces in the line of sight (LOS) environments. In this paper, we propose a new...... LOS and non line of sight (NLOS) environments. The channel capacity of the proposed method is derived for the direct path environments and it confirms the effectiveness of the proposed scheme in the LOS scenario. Moreover, solid computer simulation results confirm the effectiveness of the proposed...

  11. Spin magneto-transport in a Rashba-Dresselhaus quantum channel with single and double finger gates

    Science.gov (United States)

    Tang, Chi-Shung; Keng, Jia-An; Abdullah, Nzar Rauf; Gudmundsson, Vidar

    2017-05-01

    We address spin-resolved electronic transport properties in a Rashba-Dresselhaus quantum channel in the presence of an in-plane magnetic field. The strong Rashba-Dresselhaus effect induces an asymmetric spin-splitting energy spectrum with a spin-orbit-Zeeman gap. This asymmetric fact in energy spectrum may result in various quantum dynamic features in conductance due to the presence of finger gates. This asymmetric spin-splitting energy spectrum results in a bound state in continuum for electrons within ultralow energy regime with binding energies in order of 10-1 meV.

  12. Precision measurements of the top quark pair production cross section in the single lepton channel with the ATLAS experiment

    International Nuclear Information System (INIS)

    Heinrichs, Anna Christine

    2012-01-01

    Two precision measurements of the top quark pair production cross section in the lepton+jets channel are accomplished using data taken by the ATLAS experiment at the Large Hadron Collider at CERN. The data corresponds to proton-proton collisions taken in 2010 and 2011 at a center-of-mass energy of 7 TeV. The measurement using data from 2010 achieves an overall uncertainty of 12%, while the measurement using 2011 data reaches a precision of 6.6%. Both measurements are in good agreement with theoretical predictions in the framework of the Standard Model of particle physics.

  13. Fates of pollutants from uranium mining in floodplain of a meandering river (the Ploucnice, Czech Republic)

    Science.gov (United States)

    Matys Grygar, Tomas; Elznicova, Jitka; Majerova, Lucie; Babek, Ondrej; Kiss, Timea; Havelcova, Martina; Hosek, Michal

    2014-05-01

    tens of km downstream of the mining area). Several hotspots were formed behind the end of the channelised river reach downstream from the mining area. The analyses of the pollution hotspots conducted by other researchers in 1990s and our novel results show that maximal pollutant gamma activity (mainly U and Ra-226) in these hotspots has been transported from a meander (channel) belt towards the distal floodplain. Downstream transport (secondary pollution) from the hotspots is demonstrated by considerable Zn, Ni and U enrichment in the deposits of 2013 summer flood (25 years after termination of the primary pollution) and by the fact, that enrichment factors of Zn, Ni and U in the floodplain sediments downstream of the hotspots has still not started to decline. The persistence of the pollution of the floodplain sediments is in contrast with the activity of the Ploučnice River water, which dropped down in 1989 and afterwards to the levels from the period before the start of the uranium mining.

  14. An evaluation of a new single-use flexible bronchoscope with a large suction channel: reliability of bronchoalveolar lavage in ventilated piglets and initial clinical experience.

    Science.gov (United States)

    Mankikian, J; Ehrmann, S; Guilleminault, L; Le Fol, T; Barc, C; Ferrandière, M; Boulain, T; Dequin, P F; Guillon, A

    2014-07-01

    A single-use flexible bronchoscope with a large suction channel has become available recently and we have evaluated this innovative device. Firstly, bronchoalveolar lavage was performed and quantified in ventilated piglets. Next, the bronchoscope was evaluated in three intensive care units and a satisfaction questionnaire was carried out. Sixteen bronchoalveolar lavages were performed in piglets with a recovery rate of 83 (79-86 [72-89])% of the instilled volume. Quality and performance of all devices tested was identical. The medical satisfaction questionnaire was as follows: 'acceptable' to 'very good' for quality of aspiration, manoeuvrability and quality of vision; 'very good' to 'perfect' for setting up and insertion. This encouraging preliminary evaluation demonstrates the effectiveness of this new single-use device, which may obviate the need for disinfection procedures and, thereby, eradicate a potential vector of patient cross-contamination. © 2014 The Association of Anaesthetists of Great Britain and Ireland.

  15. Spatially multiplexed orbital-angular-momentum-encoded single photon and classical channels in a free-space optical communication link.

    Science.gov (United States)

    Ren, Yongxiong; Liu, Cong; Pang, Kai; Zhao, Jiapeng; Cao, Yinwen; Xie, Guodong; Li, Long; Liao, Peicheng; Zhao, Zhe; Tur, Moshe; Boyd, Robert W; Willner, Alan E

    2017-12-01

    We experimentally demonstrate spatial multiplexing of an orbital angular momentum (OAM)-encoded quantum channel and a classical Gaussian beam with a different wavelength and orthogonal polarization. Data rates as large as 100 MHz are achieved by encoding on two different OAM states by employing a combination of independently modulated laser diodes and helical phase holograms. The influence of OAM mode spacing, encoding bandwidth, and interference from the co-propagating Gaussian beam on registered photon count rates and quantum bit error rates is investigated. Our results show that the deleterious effects of intermodal crosstalk effects on system performance become less important for OAM mode spacing Δ≥2 (corresponding to a crosstalk value of less than -18.5  dB). The use of OAM domain can additionally offer at least 10.4 dB isolation besides that provided by wavelength and polarization, leading to a further suppression of interference from the classical channel.

  16. Experimental Study of Single Phase Flow in a Closed-Loop Cooling System with Integrated Mini-Channel Heat Sink

    Directory of Open Access Journals (Sweden)

    Lei Ma

    2016-06-01

    Full Text Available The flow and heat transfer characteristics of a closed-loop cooling system with a mini-channel heat sink for thermal management of electronics is studied experimentally. The heat sink is designed with corrugated fins to improve its heat dissipation capability. The experiments are performed using variable coolant volumetric flow rates and input heating powers. The experimental results show a high and reliable thermal performance using the heat sink with corrugated fins. The heat transfer capability is improved up to 30 W/cm2 when the base temperature is kept at a stable and acceptable level. Besides the heat transfer capability enhancement, the capability of the system to transfer heat for a long distance is also studied and a fast thermal response time to reach steady state is observed once the input heating power or the volume flow rate are varied. Under different input heat source powers and volumetric flow rates, our results suggest potential applications of the designed mini-channel heat sink in cooling microelectronics.

  17. Differential single-top-quark cross sections in t channel at 8 and 13 TeV with the CMS detector

    CERN Document Server

    Komm, Matthias

    2017-01-01

    The production of single top quarks in high energy collision events is a unique process to investigate the strength and structure of electroweak interactions. This thesis encompasses first measurements of differential single-top-quark cross sections in t channel which have been performed using data collected at center-of-mass energies of 8 and 13 TeV with the CMS detector at CERN, Switzerland. The electroweak coupling structure of the standard model of particle physics predicts only left-handed top quarks or right-handed top antiquarks to participate in electroweak interactions, resulting in the production of highly polarized top quarks via t channel. The degree of polarization is studied by measuring the cross section as a function of the polarization angle, defined as the angle between the charged lepton from the top quark decay and a spectator quark which is produced in association with the top quark. The differential cross section as a function of the polarization angle is measured in 8 TeV d...

  18. Measurement of the single-top-quark t-channel cross section in pp collisions at $ \\sqrt{s}=7 $ TeV

    Energy Technology Data Exchange (ETDEWEB)

    Chatrchyan, S.; Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Aguilo, E.; Bergauer, T.; Dragicevic, M.; Erö, J.; Fabjan, C.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hörmann, N.; Hrubec, J.; Jeitler, M.; Kiesenhofer, W.; Knünz, V.; Krammer, M.; Krätschmer, I.; Liko, D.; Mikulec, I.; Pernicka, M.; Rabady, D.; Rahbaran, B.; Rohringer, C.; Rohringer, H.; Schöfbeck, R.; Strauss, J.; Taurok, A.; Waltenberger, W.; Wulz, C. -E.; Mossolov, V.; Shumeiko, N.; Suarez Gonzalez, J.; Bansal, M.; Bansal, S.; Cornelis, T.; De Wolf, E. A.; Janssen, X.; Luyckx, S.; Mucibello, L.; Ochesanu, S.; Roland, B.; Rougny, R.; Selvaggi, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Blekman, F.; Blyweert, S.; D’Hondt, J.; Gonzalez Suarez, R.; Kalogeropoulos, A.; Maes, M.; Olbrechts, A.; Van Doninck, W.; Van Mulders, P.; Van Onsem, G. P.; Villella, I.; Clerbaux, B.; De Lentdecker, G.; Dero, V.; Gay, A. P. R.; Hreus, T.; Léonard, A.; Marage, P. E.; Mohammadi, A.; Reis, T.; Thomas, L.; Vander Velde, C.; Vanlaer, P.; Wang, J.; Adler, V.; Beernaert, K.; Cimmino, A.; Costantini, S.; Garcia, G.; Grunewald, M.; Klein, B.; Lellouch, J.; Marinov, A.; Mccartin, J.; Ocampo Rios, A. A.; Ryckbosch, D.; Strobbe, N.; Thyssen, F.; Tytgat, M.; Walsh, S.; Yazgan, E.; Zaganidis, N.; Basegmez, S.; Bruno, G.; Castello, R.; Ceard, L.; Delaere, C.; du Pree, T.; Favart, D.; Forthomme, L.; Giammanco, A.; Hollar, J.; Lemaitre, V.; Liao, J.; Militaru, O.; Nuttens, C.; Pagano, D.; Pin, A.; Piotrzkowski, K.; Vizan Garcia, J. M.; Beliy, N.; Caebergs, T.; Daubie, E.; Hammad, G. H.; Alves, G. A.; Correa Martins, M.; Martins, T.; Pol, M. E.; Souza, M. H. G.; Aldá, W. L.; Carvalho, W.; Custódio, A.; Da Costa, E. M.; De Jesus Damiao, D.; De Oliveira Martins, C.; Fonseca De Souza, S.; Malbouisson, H.; Malek, M.; Matos Figueiredo, D.; Mundim, L.; Nogima, H.; Prado Da Silva, W. L.; Santoro, A.; Soares Jorge, L.; Sznajder, A.; Vilela Pereira, A.; Anjos, T. S.; Bernardes, C. A.; Dias, F. A.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Lagana, C.; Marinho, F.; Mercadante, P. G.; Novaes, S. F.; Padula, Sandra S.; Genchev, V.; Iaydjiev, P.; Piperov, S.; Rodozov, M.; Stoykova, S.; Sultanov, G.; Tcholakov, V.; Trayanov, R.; Vutova, M.; Dimitrov, A.; Hadjiiska, R.; Kozhuharov, V.; Litov, L.; Pavlov, B.; Petkov, P.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Jiang, C. H.; Liang, D.; Liang, S.; Meng, X.; Tao, J.; Wang, J.; Wang, X.; Wang, Z.; Xiao, H.; Xu, M.; Zang, J.; Zhang, Z.; Asawatangtrakuldee, C.; Ban, Y.; Guo, Y.; Li, W.; Liu, S.; Mao, Y.; Qian, S. J.; Teng, H.; Wang, D.; Zhang, L.; Zou, W.; Avila, C.; Gomez, J. P.; Gomez Moreno, B.; Osorio Oliveros, A. F.; Sanabria, J. C.; Godinovic, N.; Lelas, D.; Plestina, R.; Polic, D.; Puljak, I.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Duric, S.; Kadija, K.; Luetic, J.; Mekterovic, D.; Morovic, S.; Attikis, A.; Galanti, M.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Finger, M.; Finger, M.; Assran, Y.; Bakhet, N.; Elgammal, S.; Ellithi Kamel, A.; Khalil, S.; Kuotb Awad, A. M.; Mahmoud, M. A.; Radi, A.; Kadastik, M.; Müntel, M.; Raidal, M.; Rebane, L.; Tiko, A.; Eerola, P.; Fedi, G.; Voutilainen, M.; Härkönen, J.; Heikkinen, A.; Karimäki, V.; Kinnunen, R.; Kortelainen, M. J.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Mäenpää, T.; Peltola, T.; Tuominen, E.; Tuominiemi, J.; Tuovinen, E.; Ungaro, D.; Wendland, L.; Banzuzi, K.; Karjalainen, A.; Korpela, A.; Tuuva, T.; Besancon, M.; Choudhury, S.; Dejardin, M.; Denegri, D.; Fabbro, B.; Faure, J. L.; Ferri, F.; Ganjour, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Locci, E.; Malcles, J.; Millischer, L.; Nayak, A.; Rander, J.; Rosowsky, A.; Titov, M.; Baffioni, S.; Beaudette, F.; Benhabib, L.; Bianchini, L.; Bluj, M.; Busson, P.; Charlot, C.; Daci, N.; Dahms, T.; Dalchenko, M.; Dobrzynski, L.; Florent, A.; Granier de Cassagnac, R.; Haguenauer, M.; Miné, P.; Mironov, C.; Naranjo, I. N.; Nguyen, M.; Ochando, C.; Paganini, P.; Sabes, D.; Salerno, R.; Sirois, Y.; Veelken, C.; Zabi, A.; Agram, J. -L.; Andrea, J.; Bloch, D.; Bodin, D.; Brom, J. -M.; Cardaci, M.; Chabert, E. C.; Collard, C.; Conte, E.; Drouhin, F.; Fontaine, J. -C.; Gelé, D.; Goerlach, U.; Juillot, P.; Le Bihan, A. -C.; Van Hove, P.; Fassi, F.; Mercier, D.; Beauceron, S.; Beaupere, N.; Bondu, O.; Boudoul, G.; Chasserat, J.; Chierici, R.; Contardo, D.; Depasse, P.; El Mamouni, H.; Fay, J.; Gascon, S.; Gouzevitch, M.; Ille, B.; Kurca, T.; Lethuillier, M.; Mirabito, L.; Perries, S.; Sgandurra, L.; Sordini, V.; Tschudi, Y.; Verdier, P.; Viret, S.; Roinishvili, V.; Autermann, C.; Beranek, S.; Calpas, B.; Edelhoff, M.; Feld, L.; Heracleous, N.; Hindrichs, O.; Jussen, R.; Klein, K.; Merz, J.; Ostapchuk, A.; Perieanu, A.; Raupach, F.; Sammet, J.; Schael, S.; Sprenger, D.; Weber, H.; Wittmer, B.; Zhukov, V.; Ata, M.; Caudron, J.; Dietz-Laursonn, E.; Duchardt, D.; Erdmann, M.; Fischer, R.; Güth, A.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Klingebiel, D.; Komm, M.; Kreuzer, P.; Marquardt, B.; Merschmeyer, M.; Meyer, A.; Olschewski, M.; Papacz, P.; Pieta, H.; Reithler, H.; Schmitz, S. A.; Sonnenschein, L.; Steggemann, J.; Teyssier, D.; Thüer, S.; Weber, M.; Bontenackels, M.; Cherepanov, V.; Erdogan, Y.; Flügge, G.; Geenen, H.; Geisler, M.; Haj Ahmad, W.; Hoehle, F.; Kargoll, B.; Kress, T.; Kuessel, Y.; Lingemann, J.; Nowack, A.; Perchalla, L.; Pooth, O.; Sauerland, P.; Stahl, A.; Aldaya Martin, M.; Behr, J.; Behrenhoff, W.; Behrens, U.; Bergholz, M.; Bethani, A.; Borras, K.; Burgmeier, A.; Cakir, A.; Calligaris, L.; Campbell, A.; Castro, E.; Costanza, F.; Dammann, D.; Diez Pardos, C.; Eckerlin, G.; Eckstein, D.; Flucke, G.; Geiser, A.; Glushkov, I.; Gunnellini, P.; Habib, S.; Hauk, J.; Hellwig, G.; Jung, H.; Kasemann, M.; Katsas, P.; Kleinwort, C.; Kluge, H.; Knutsson, A.; Krämer, M.; Krücker, D.; Kuznetsova, E.; Lange, W.; Leonard, J.; Lohmann, W.; Lutz, B.; Mankel, R.; Marfin, I.; Marienfeld, M.; Melzer-Pellmann, I. -A.; Meyer, A. B.; Mnich, J.; Mussgiller, A.; Naumann-Emme, S.; Novgorodova, O.; Olzem, J.; Perrey, H.; Petrukhin, A.; Pitzl, D.; Raspereza, A.; Ribeiro Cipriano, P. M.; Riedl, C.; Ron, E.; Rosin, M.; Salfeld-Nebgen, J.; Schmidt, R.; Schoerner-Sadenius, T.; Sen, N.; Spiridonov, A.; Stein, M.; Walsh, R.; Wissing, C.; Blobel, V.; Enderle, H.; Erfle, J.; Gebbert, U.; Görner, M.; Gosselink, M.; Haller, J.; Hermanns, T.; Höing, R. S.; Kaschube, K.; Kaussen, G.; Kirschenmann, H.; Klanner, R.; Lange, J.; Nowak, F.; Peiffer, T.; Pietsch, N.; Rathjens, D.; Sander, C.; Schettler, H.; Schleper, P.; Schlieckau, E.; Schmidt, A.; Schröder, M.; Schum, T.; Seidel, M.; Sibille, J.; Sola, V.; Stadie, H.; Steinbrück, G.; Thomsen, J.; Vanelderen, L.; Barth, C.; Berger, J.; Böser, C.; Chwalek, T.; De Boer, W.; Descroix, A.; Dierlamm, A.; Feindt, M.; Guthoff, M.; Hackstein, C.; Hansen, J.; Hartmann, F.; Hauth, T.; Heinrich, M.; Held, H.; Hoffmann, K. H.; Husemann, U.; Katkov, I.; Komaragiri, J. R.; Lobelle Pardo, P.; Martschei, D.; Mueller, S.; Müller, Th.; Niegel, M.; Nürnberg, A.; Oberst, O.; Oehler, A.; Ott, J.; Quast, G.; Rabbertz, K.; Ratnikov, F.; Ratnikova, N.; Röcker, S.; Schilling, F. -P.; Schott, G.; Simonis, H. J.; Stober, F. M.; Troendle, D.; Ulrich, R.; Wagner-Kuhr, J.; Wayand, S.; Weiler, T.; Zeise, M.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Kesisoglou, S.; Kyriakis, A.; Loukas, D.; Manolakos, I.; Markou, A.; Markou, C.; Ntomari, E.; Gouskos, L.; Mertzimekis, T. J.; Panagiotou, A.; Saoulidou, N.; Evangelou, I.; Foudas, C.; Kokkas, P.; Manthos, N.; Papadopoulos, I.; Patras, V.; Bencze, G.; Hajdu, C.; Hidas, P.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Beni, N.; Czellar, S.; Molnar, J.; Palinkas, J.; Szillasi, Z.; Karancsi, J.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Beri, S. B.; Bhatnagar, V.; Dhingra, N.; Gupta, R.; Kaur, M.; Mehta, M. Z.; Nishu, N.; Saini, L. K.; Sharma, A.; Singh, J. B.; Kumar, Ashok; Kumar, Arun; Ahuja, S.; Bhardwaj, A.; Choudhary, B. C.; Malhotra, S.; Naimuddin, M.; Ranjan, K.; Sharma, V.; Shivpuri, R. K.; Banerjee, S.; Bhattacharya, S.; Dutta, S.; Gomber, B.; Jain, Sa.; Jain, Sh.; Khurana, R.; Sarkar, S.; Sharan, M.; Abdulsalam, A.; Dutta, D.; Kailas, S.; Kumar, V.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Aziz, T.; Ganguly, S.; Guchait, M.; Gurtu, A.; Maity, M.; Majumder, G.; Mazumdar, K.; Mohanty, G. B.; Parida, B.; Sudhakar, K.; Wickramage, N.; Banerjee, S.; Dugad, S.; Arfaei, H.; Bakhshiansohi, H.; Etesami, S. M.; Fahim, A.; Hashemi, M.; Hesari, H.; Jafari, A.; Khakzad, M.; Mohammadi Najafabadi, M.; Paktinat Mehdiabadi, S.; Safarzadeh, B.; Zeinali, M.; Abbrescia, M.; Barbone, L.; Calabria, C.; Chhibra, S. S.; Colaleo, A.; Creanza, D.; De Filippis, N.; De Palma, M.; Fiore, L.; Iaselli, G.; Maggi, G.; Maggi, M.; Marangelli, B.; My, S.; Nuzzo, S.; Pacifico, N.; Pompili, A.; Pugliese, G.; Selvaggi, G.; Silvestris, L.; Singh, G.; Venditti, R.; Verwilligen, P.; Zito, G.; Abbiendi, G.; Benvenuti, A. C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Brigliadori, L.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Meneghelli, M.; Montanari, A.; Navarria, F. L.; Odorici, F.; Perrotta, A.; Primavera, F.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Travaglini, R.; Albergo, S.; Cappello, G.; Chiorboli, M.; Costa, S.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Ciulli, V.; Civinini, C.; D’Alessandro, R.; Focardi, E.; Frosali, S.; Gallo, E.; Gonzi, S.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Tropiano, A.; Benussi, L.; Bianco, S.; Colafranceschi, S.; Fabbri, F.; Piccolo, D.; Fabbricatore, P.; Musenich, R.; Tosi, S.; Benaglia, A.; De Guio, F.; Di Matteo, L.; Fiorendi, S.; Gennai, S.; Ghezzi, A.; Malvezzi, S.; Manzoni, R. A.; Martelli, A.; Massironi, A.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Ragazzi, S.; Redaelli, N.; Sala, S.; Tabarelli de Fatis, T.; Buontempo, S.; Carrillo Montoya, C. A.; Cavallo, N.; De Cosa, A.; Dogangun, O.; Fabozzi, F.; Iorio, A. O. M.; Lista, L.; Meola, S.; Merola, M.; Paolucci, P.; Azzi, P.; Bacchetta, N.; Bellan, P.; Bisello, D.; Branca, A.; Carlin, R.; Checchia, P.; Dorigo, T.; Dosselli, U.; Gasparini, F.; Gasparini, U.; Gozzelino, A.; Kanishchev, K.; Lacaprara, S.; Lazzizzera, I.; Margoni, M.; Meneguzzo, A. T.; Nespolo, M.; Pazzini, J.; Ronchese, P.; Simonetto, F.; Torassa, E.; Vanini, S.; Zotto, P.; Zumerle, G.; Gabusi, M.; Ratti, S. P.; Riccardi, C.; Torre, P.; Vitulo, P.; Biasini, M.; Bilei, G. M.; Fanò, L.; Lariccia, P.; Mantovani, G.; Menichelli, M.; Nappi, A.; Romeo, F.; Saha, A.; Santocchia, A.; Spiezia, A.; Taroni, S.; Azzurri, P.; Bagliesi, G.; Boccali, T.; Broccolo, G.; Castaldi, R.; D’Agnolo, R. T.; Dell’Orso, R.; Fiori, F.; Foà, L.; Giassi, A.; Kraan, A.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Palla, F.; Rizzi, A.; Serban, A. T.; Spagnolo, P.; Squillacioti, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; Del Re, D.; Diemoz, M.; Fanelli, C.; Grassi, M.; Longo, E.; Meridiani, P.; Micheli, F.; Nourbakhsh, S.; Organtini, G.; Paramatti, R.; Rahatlou, S.; Sigamani, M.; Soffi, L.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Biino, C.; Cartiglia, N.; Casasso, S.; Costa, M.; Demaria, N.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Musich, M.; Obertino, M. M.; Pastrone, N.; Pelliccioni, M.; Potenza, A.; Romero, A.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; Marone, M.; Montanino, D.; Penzo, A.; Schizzi, A.; Kim, T. Y.; Nam, S. K.; Chang, S.; Kim, D. H.; Kim, G. N.; Kong, D. J.; Park, H.; Son, D. C.; Son, T.; Kim, J. Y.; Kim, Zero J.; Song, S.; Choi, S.; Gyun, D.; Hong, B.; Jo, M.; Kim, H.; Kim, T. J.; Lee, K. S.; Moon, D. H.; Park, S. K.; Roh, Y.; Choi, M.; Kim, J. H.; Park, C.; Park, I. C.; Park, S.; Ryu, G.; Choi, Y.; Choi, Y. K.; Goh, J.; Kim, M. S.; Kwon, E.; Lee, B.; Lee, J.; Lee, S.; Seo, H.; Yu, I.; Bilinskas, M. J.; Grigelionis, I.; Janulis, M.; Juodagalvis, A.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; Heredia-de La Cruz, I.; Lopez-Fernandez, R.; Martínez-Ortega, J.; Sánchez-Hernández, A.; Villasenor-Cendejas, L. M.; Carrillo Moreno, S.; Vazquez Valencia, F.; Salazar Ibarguen, H. A.; Casimiro Linares, E.; Morelos Pineda, A.; Reyes-Santos, M. A.; Krofcheck, D.; Bell, A. J.; Butler, P. H.; Doesburg, R.; Reucroft, S.; Silverwood, H.; Ahmad, M.; Asghar, M. I.; Butt, J.; Hoorani, H. R.; Khalid, S.; Khan, W. A.; Khurshid, T.; Qazi, S.; Shah, M. A.; Shoaib, M.; Bialkowska, H.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Romanowska-Rybinska, K.; Szleper, M.; Wrochna, G.; Zalewski, P.; Brona, G.; Bunkowski, K.; Cwiok, M.; Dominik, W.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Misiura, M.; Almeida, N.; Bargassa, P.; David, A.; Faccioli, P.; Ferreira Parracho, P. G.; Gallinaro, M.; Seixas, J.; Varela, J.; Vischia, P.; Belotelov, I.; Bunin, P.; Gavrilenko, M.; Golutvin, I.; Gorbunov, I.; Kamenev, A.; Karjavin, V.; Kozlov, G.; Lanev, A.; Malakhov, A.; Moisenz, P.; Palichik, V.; Perelygin, V.; Shmatov, S.; Smirnov, V.; Volodko, A.; Zarubin, A.; Evstyukhin, S.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Levchenko, P.; Murzin, V.; Oreshkin, V.; Smirnov, I.; Sulimov, V.; Uvarov, L.; Vavilov, S.; Vorobyev, A.; Vorobyev, An.; Andreev, Yu.; Dermenev, A.; Gninenko, S.; Golubev, N.; Kirsanov, M.; Krasnikov, N.; Matveev, V.; Pashenkov, A.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Erofeeva, M.; Gavrilov, V.; Kossov, M.; Lychkovskaya, N.; Popov, V.; Safronov, G.; Semenov, S.; Shreyber, I.; Stolin, V.; Vlasov, E.; Zhokin, A.; Belyaev, A.; Boos, E.; Dubinin, M.; Dudko, L.; Ershov, A.; Gribushin, A.; Klyukhin, V.; Kodolova, O.; Lokhtin, I.; Markina, A.; Obraztsov, S.; Perfilov, M.; Petrushanko, S.; Popov, A.; Sarycheva, L.; Savrin, V.; Snigirev, A.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Leonidov, A.; Mesyats, G.; Rusakov, S. V.; Vinogradov, A.; Azhgirey, I.; Bayshev, I.; Bitioukov, S.; Grishin, V.; Kachanov, V.; Konstantinov, D.; Krychkine, V.; Petrov, V.; Ryutin, R.; Sobol, A.; Tourtchanovitch, L.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Adzic, P.; Djordjevic, M.; Ekmedzic, M.; Krpic, D.; Milosevic, J.; Aguilar-Benitez, M.; Alcaraz Maestre, J.; Arce, P.; Battilana, C.; Calvo, E.; Cerrada, M.; Chamizo Llatas, M.; Colino, N.; De La Cruz, B.; Delgado Peris, A.; Domínguez Vázquez, D.; Fernandez Bedoya, C.; Fernández Ramos, J. P.; Ferrando, A.; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Gonzalez Lopez, O.; Goy Lopez, S.; Hernandez, J. M.; Josa, M. I.; Merino, G.; Puerta Pelayo, J.; Quintario Olmeda, A.; Redondo, I.; Romero, L.; Santaolalla, J.; Soares, M. S.; Willmott, C.; Albajar, C.; Codispoti, G.; de Trocóniz, J. F.; Brun, H.; Cuevas, J.; Fernandez Menendez, J.; Folgueras, S.; Gonzalez Caballero, I.; Lloret Iglesias, L.; Piedra Gomez, J.; Brochero Cifuentes, J. A.; Cabrillo, I. J.; Calderon, A.; Chuang, S. H.; Duarte Campderros, J.; Felcini, M.; Fernandez, M.; Gomez, G.; Gonzalez Sanchez, J.; Graziano, A.; Jorda, C.; Lopez Virto, A.; Marco, J.; Marco, R.; Martinez Rivero, C.; Matorras, F.; Munoz Sanchez, F. J.; Rodrigo, T.; Rodríguez-Marrero, A. Y.; Ruiz-Jimeno, A.; Scodellaro, L.; Vila, I.; Vilar Cortabitarte, R.; Abbaneo, D.; Auffray, E.; Auzinger, G.; Bachtis, M.; Baillon, P.; Ball, A. H.; Barney, D.; Benitez, J. F.; Bernet, C.; Bianchi, G.; Bloch, P.; Bocci, A.; Bonato, A.; Botta, C.; Breuker, H.; Camporesi, T.; Cerminara, G.; Christiansen, T.; Coarasa Perez, J. A.; D’Enterria, D.; Dabrowski, A.; De Roeck, A.; Di Guida, S.; Dobson, M.; Dupont-Sagorin, N.; Elliott-Peisert, A.; Frisch, B.; Funk, W.; Georgiou, G.; Giffels, M.; Gigi, D.; Gill, K.; Giordano, D.; Girone, M.; Giunta, M.; Glege, F.; Gomez-Reino Garrido, R.; Govoni, P.; Gowdy, S.; Guida, R.; Gundacker, S.; Hammer, J.; Hansen, M.; Harris, P.; Hartl, C.; Harvey, J.; Hegner, B.; Hinzmann, A.; Innocente, V.; Janot, P.; Kaadze, K.; Karavakis, E.; Kousouris, K.; Lecoq, P.; Lee, Y. -J.; Lenzi, P.; Lourenço, C.; Magini, N.; Mäki, T.; Malberti, M.; Malgeri, L.; Mannelli, M.; Masetti, L.; Meijers, F.; Mersi, S.; Meschi, E.; Moser, R.; Mozer, M. U.; Mulders, M.; Musella, P.; Nesvold, E.; Orsini, L.; Palencia Cortezon, E.; Perez, E.; Perrozzi, L.; Petrilli, A.; Pfeiffer, A.; Pierini, M.; Pimiä, M.; Piparo, D.; Polese, G.; Quertenmont, L.; Racz, A.; Reece, W.; Rodrigues Antunes, J.; Rolandi, G.; Rovelli, C.; Rovere, M.; Sakulin, H.; Santanastasio, F.; Schäfer, C.; Schwick, C.; Segoni, I.; Sekmen, S.; Sharma, A.; Siegrist, P.; Silva, P.; Simon, M.; Sphicas, P.; Spiga, D.; Tsirou, A.; Veres, G. I.; Vlimant, J. R.; Wöhri, H. K.; Worm, S. D.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Gabathuler, K.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; König, S.; Kotlinski, D.; Langenegger, U.; Meier, F.; Renker, D.; Rohe, T.; Bäni, L.; Bortignon, P.; Buchmann, M. A.; Casal, B.; Chanon, N.; Deisher, A.; Dissertori, G.; Dittmar, M.; Donegà, M.; Dünser, M.; Eller, P.; Eugster, J.; Freudenreich, K.; Grab, C.; Hits, D.; Lecomte, P.; Lustermann, W.; Marini, A. C.; Martinez Ruiz del Arbol, P.; Mohr, N.; Moortgat, F.; Nägeli, C.; Nef, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pape, L.; Pauss, F.; Peruzzi, M.; Ronga, F. J.; Rossini, M.; Sala, L.; Sanchez, A. K.; Starodumov, A.; Stieger, B.; Takahashi, M.; Tauscher, L.; Thea, A.; Theofilatos, K.; Treille, D.; Urscheler, C.; Wallny, R.; Weber, H. A.; Wehrli, L.; Amsler, C.; Chiochia, V.; De Visscher, S.; Favaro, C.; Ivova Rikova, M.; Kilminster, B.; Millan Mejias, B.; Otiougova, P.; Robmann, P.; Snoek, H.; Tupputi, S.; Verzetti, M.; Chang, Y. H.; Chen, K. H.; Ferro, C.; Kuo, C. M.; Li, S. W.; Lin, W.; Lu, Y. J.; Singh, A. P.; Volpe, R.; Yu, S. S.; Bartalini, P.; Chang, P.; Chang, Y. H.; Chang, Y. W.; Chao, Y.; Chen, K. F.; Dietz, C.; Grundler, U.; Hou, W. -S.; Hsiung, Y.; Kao, K. Y.; Lei, Y. J.; Lu, R. -S.; Majumder, D.; Petrakou, E.; Shi, X.; Shiu, J. G.; Tzeng, Y. M.; Wan, X.; Wang, M.; Asavapibhop, B.; Srimanobhas, N.; Adiguzel, A.; Bakirci, M. N.; Cerci, S.; Dozen, C.; Dumanoglu, I.; Eskut, E.; Girgis, S.; Gokbulut, G.; Gurpinar, E.; Hos, I.; Kangal, E. E.; Karaman, T.; Karapinar, G.; Kayis Topaksu, A.; Onengut, G.; Ozdemir, K.; Ozturk, S.; Polatoz, A.; Sogut, K.; Sunar Cerci, D.; Tali, B.; Topakli, H.; Vergili, L. N.; Vergili, M.; Akin, I. V.; Aliev, T.; Bilin, B.; Bilmis, S.; Deniz, M.; Gamsizkan, H.; Guler, A. M.; Ocalan, K.; Ozpineci, A.; Serin, M.; Sever, R.; Surat, U. E.; Yalvac, M.; Yildirim, E.; Zeyrek, M.; Gülmez, E.; Isildak, B.; Kaya, M.; Kaya, O.; Ozkorucuklu, S.; Sonmez, N.; Cankocak, K.; Levchuk, L.; Brooke, J. J.; Clement, E.; Cussans, D.; Flacher, H.; Frazier, R.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Kreczko, L.; Metson, S.; Newbold, D. M.; Nirunpong, K.; Poll, A.; Senkin, S.; Smith, V. J.; Williams, T.; Basso, L.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Jackson, J.; Kennedy, B. W.; Olaiya, E.; Petyt, D.; Radburn-Smith, B. C.; Shepherd-Themistocleous, C. H.; Tomalin, I. R.; Womersley, W. J.; Bainbridge, R.; Ball, G.; Beuselinck, R.; Buchmuller, O.; Colling, D.; Cripps, N.; Cutajar, M.; Dauncey, P.; Davies, G.; Della Negra, M.; Ferguson, W.; Fulcher, J.; Futyan, D.; Gilbert, A.; Guneratne Bryer, A.; Hall, G.; Hatherell, Z.; Hays, J.; Iles, G.; Jarvis, M.; Karapostoli, G.; Lyons, L.; Magnan, A. -M.; Marrouche, J.; Mathias, B.; Nandi, R.; Nash, J.; Nikitenko, A.; Pela, J.; Pesaresi, M.; Petridis, K.; Pioppi, M.; Raymond, D. M.; Rogerson, S.; Rose, A.; Ryan, M. J.; Seez, C.; Sharp, P.; Sparrow, A.; Stoye, M.; Tapper, A.; Vazquez Acosta, M.; Virdee, T.; Wakefield, S.; Wardle, N.; Whyntie, T.; Chadwick, M.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Leggat, D.; Leslie, D.; Martin, W.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Hatakeyama, K.; Liu, H.; Scarborough, T.; Charaf, O.; Henderson, C.; Rumerio, P.; Avetisyan, A.; Bose, T.; Fantasia, C.; Heister, A.; St. John, J.; Lawson, P.; Lazic, D.; Rohlf, J.; Sperka, D.; Sulak, L.; Alimena, J.; Bhattacharya, S.; Christopher, G.; Cutts, D.; Demiragli, Z.; Ferapontov, A.; Garabedian, A.; Heintz, U.; Jabeen, S.; Kukartsev, G.; Laird, E.; Landsberg, G.; Luk, M.; Narain, M.; Nguyen, D.; Segala, M.; Sinthuprasith, T.; Speer, T.; Breedon, R.; Breto, G.; Calderon De La Barca Sanchez, M.; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Dolen, J.; Erbacher, R.; Gardner, M.; Houtz, R.; Ko, W.; Kopecky, A.; Lander, R.; Mall, O.; Miceli, T.; Pellett, D.; Ricci-tam, F.; Rutherford, B.; Searle, M.; Smith, J.; Squires, M.; Tripathi, M.; Vasquez Sierra, R.