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Sample records for simple high performance

  1. Simple, parallel, high-performance virtual machines for extreme computations

    International Nuclear Information System (INIS)

    Chokoufe Nejad, Bijan; Ohl, Thorsten; Reuter, Jurgen

    2014-11-01

    We introduce a high-performance virtual machine (VM) written in a numerically fast language like Fortran or C to evaluate very large expressions. We discuss the general concept of how to perform computations in terms of a VM and present specifically a VM that is able to compute tree-level cross sections for any number of external legs, given the corresponding byte code from the optimal matrix element generator, O'Mega. Furthermore, this approach allows to formulate the parallel computation of a single phase space point in a simple and obvious way. We analyze hereby the scaling behaviour with multiple threads as well as the benefits and drawbacks that are introduced with this method. Our implementation of a VM can run faster than the corresponding native, compiled code for certain processes and compilers, especially for very high multiplicities, and has in general runtimes in the same order of magnitude. By avoiding the tedious compile and link steps, which may fail for source code files of gigabyte sizes, new processes or complex higher order corrections that are currently out of reach could be evaluated with a VM given enough computing power.

  2. Analysis of Simvastatin using a Simple and Fast High Performance ...

    African Journals Online (AJOL)

    performance liquid chromatography (RP-HPLC) analytical method for the lipid lowering drug, simvastatin, and to apply the developed method to study the solubility of the drug in various ..... Takano T, Abe S, Hata S. A selected ion monitoring.

  3. A simple, high performance Thomson scattering diagnostic for high temperature plasma research

    International Nuclear Information System (INIS)

    Hartog, D.J.D.; Cekic, M.

    1994-02-01

    This Thomson scattering diagnostic is used to measure the electron temperature and density of the plasma in the MST reversed-field pinch, a magnetic confinement fusion research device. This diagnostic system is unique for its type in that it combines high performance with simple design and low cost components. In the design of this instrument, careful attention was given to the suppression of stray laser line light with simple and effective beam dumps, viewing dumps, aperatures, and a holographic edge filter. This allows the use of a single grating monochromator for dispersion of the Thomson scattered spectrum onto the microchannel plate detector. Alignment and calibration procedures for the laser beam delivery system, the scattered light collection system, and the spectrometer and detector are described. A sample Thomson scattered spectrum illustrates typical data

  4. Determination of Urine Albumin by New Simple High-Performance Liquid Chromatography Method.

    Science.gov (United States)

    Klapkova, Eva; Fortova, Magdalena; Prusa, Richard; Moravcova, Libuse; Kotaska, Karel

    2016-11-01

    A simple high-performance liquid chromatography (HPLC) method was developed for the determination of albumin in patients' urine samples without coeluting proteins and was compared with the immunoturbidimetric determination of albumin. Urine albumin is important biomarker in diabetic patients, but part of it is immuno-nonreactive. Albumin was determined by high-performance liquid chromatography (HPLC), UV detection at 280 nm, Zorbax 300SB-C3 column. Immunoturbidimetric analysis was performed using commercial kit on automatic biochemistry analyzer COBAS INTEGRA ® 400, Roche Diagnostics GmbH, Manheim, Germany. The HLPC method was fully validated. No significant interference with other proteins (transferrin, α-1-acid glycoprotein, α-1-antichymotrypsin, antitrypsin, hemopexin) was found. The results from 301 urine samples were compared with immunochemical determination. We found a statistically significant difference between these methods (P = 0.0001, Mann-Whitney test). New simple HPLC method was developed for the determination of urine albumin without coeluting proteins. Our data indicate that the HPLC method is highly specific and more sensitive than immunoturbidimetry. © 2016 Wiley Periodicals, Inc.

  5. A simple high-performance liquid chromatographic practical approach for determination of flurbiprofen

    Directory of Open Access Journals (Sweden)

    Muhammad Akhlaq

    2011-01-01

    Full Text Available A simple, rapid, sensitive, and specific high-performance liquid chromatography (HPLC assay for flurbiprofen has been developed and validated practically. The chromatography was conducted using Gemini C18 column (5 μm; 4.6 mm × 250 mm, Phenomenex, California, USA. The mobile phase containing disodium hydrogen phosphate solution (30 mM pH 7.0 and acetonitrile (50:50; and the isocratic flow rate of 1.0 ml/min were used in the current study. Detection was made at 247 nm. The calibration curve was linear (r ≥ 0.9996 over the concentration range of 5-50 mm/ml. Mean percentage (% recovery ± % relative standard deviation (RSD ranged from 97.07 ± 0.008 to 103.66 ± 0.013. Within-day and between-day precision were also in acceptable range of 98.83 ± 0.004 to 104.56 ± 0.009. In order to confirm the practical applicability of the method developed, flurbiprofen controlled release matrix tablets were subjected to the dissolution studies and the release rate was analyzed. The reported HPLC for flurbiprofen provides several advantages of simplicity, high specificity, accuracy, and very short run-cycle time. It is suggested that the method should be used for the routine quality control analysis of flurbiprofen pure drug and its dosage forms.

  6. Simple Quantification of Pentosidine in Human Urine and Plasma by High-Performance Liquid Chromatography

    Directory of Open Access Journals (Sweden)

    Ji Sang Lee

    2017-01-01

    Full Text Available Pentosidine is an advanced glycation end-product (AGE and fluorescent cross-link compound. A simple high-performance liquid chromatographic (HPLC method was developed for the detection and quantification of pentosidine in human urine and plasma. The mobile phase used a gradient system to improve separation of pentosidine from endogenous peaks, and chromatograms were monitored by fluorescent detector set at excitation and emission wavelengths of 328 and 378 nm, respectively. The retention time for pentosidine was 24.3 min and the lower limits of quantification (LLOQ in human urine and plasma were 1 nM. The intraday assay precisions (coefficients of variation were generally low and found to be in the range of 5.19–7.49% and 4.96–8.78% for human urine and plasma, respectively. The corresponding values of the interday assay precisions were 9.45% and 4.27%. Accuracies (relative errors ranged from 87.9% to 115%. Pentosidine was stable in a range of pH solutions, human urine, and plasma. In summary, this HPLC method can be applied in future preclinical and clinical evaluation of pentosidine in the diabetic patients.

  7. Novel surgical performance evaluation approximates Standardized Incidence Ratio with high accuracy at simple means.

    Science.gov (United States)

    Gabbay, Itay E; Gabbay, Uri

    2013-01-01

    Excess adverse events may be attributable to poor surgical performance but also to case-mix, which is controlled through the Standardized Incidence Ratio (SIR). SIR calculations can be complicated, resource consuming, and unfeasible in some settings. This article suggests a novel method for SIR approximation. In order to evaluate a potential SIR surrogate measure we predefined acceptance criteria. We developed a new measure - Approximate Risk Index (ARI). "Number Needed for Event" (NNE) is the theoretical number of patients needed "to produce" one adverse event. ARI is defined as the quotient of the group of patients needed for no observed events Ge by total patients treated Ga. Our evaluation compared 2500 surgical units and over 3 million heterogeneous risk surgical patients that were induced through a computerized simulation. Surgical unit's data were computed for SIR and ARI to evaluate compliance with the predefined criteria. Approximation was evaluated by correlation analysis and performance prediction capability by Receiver Operating Characteristics (ROC) analysis. ARI strongly correlates with SIR (r(2) = 0.87, p 0.9) 87% sensitivity and 91% specificity. ARI provides good approximation of SIR and excellent prediction capability. ARI is simple and cost-effective as it requires thorough risk evaluation of only the adverse events patients. ARI can provide a crucial screening and performance evaluation quality control tool. The ARI method may suit other clinical and epidemiological settings where relatively small fraction of the entire population is affected. Copyright © 2013 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  8. A simple subcritical chromatographic test for an extended ODS high performance liquid chromatography column classification.

    Science.gov (United States)

    Lesellier, Eric; Tchapla, Alain

    2005-12-23

    This paper describes a new test designed in subcritical fluid chromatography (SFC) to compare the commercial C18 stationary phase properties. This test provides, from a single analysis of carotenoid pigments, the absolute hydrophobicity, the silanol activity and the steric separation factor of the ODS stationary phases. Both the choice of the analytical conditions and the validation of the information obtained from the chromatographic measurements are detailed. Correlations of the carotenoid test results with results obtained from other tests (Tanaka, Engelhard, Sander and Wise) performed both in SFC and HPLC are discussed. Two separation factors, calculated from the retention of carotenoid pigments used as probe, allowed to draw a first classification diagram. Columns, which present identical chromatographic behaviors are located in the same area on this diagram. This location can be related to the stationary phase properties: endcapping treatments, bonding density, linkage functionality, specific area or silica pore diameter. From the first classification, eight groups of columns are distinguished. One group of polymer coated silica, three groups of polymeric octadecyl phases, depending on the pore size and the endcapping treatment, and four groups of monomeric stationary phases. An additional classification of the four monomeric groups allows the comparison of these stationary phases inside each group by using the total hydrophobicity. One hundred and twenty-nine columns were analysed by this simple and rapid test, which allows a comparison of columns with the aim of helping along their choice in HPLC.

  9. A simple high performance liquid chromatography method for analyzing paraquat in soil solution samples.

    Science.gov (United States)

    Ouyang, Ying; Mansell, Robert S; Nkedi-Kizza, Peter

    2004-01-01

    A high performance liquid chromatography (HPLC) method with UV detection was developed to analyze paraquat (1,1'-dimethyl-4,4'-dipyridinium dichloride) herbicide content in soil solution samples. The analytical method was compared with the liquid scintillation counting (LSC) method using 14C-paraquat. Agreement obtained between the two methods was reasonable. However, the detection limit for paraquat analysis was 0.5 mg L(-1) by the HPLC method and 0.05 mg L(-1) by the LSC method. The LSC method was, therefore, 10 times more precise than the HPLC method for solution concentrations less than 1 mg L(-1). In spite of the high detection limit, the UC (nonradioactive) HPLC method provides an inexpensive and environmentally safe means for determining paraquat concentration in soil solution compared with the 14C-LSC method.

  10. A simple but highly effective approach to evaluate the prognostic performance of gene expression signatures.

    Directory of Open Access Journals (Sweden)

    Maud H W Starmans

    Full Text Available BACKGROUND: Highly parallel analysis of gene expression has recently been used to identify gene sets or 'signatures' to improve patient diagnosis and risk stratification. Once a signature is generated, traditional statistical testing is used to evaluate its prognostic performance. However, due to the dimensionality of microarrays, this can lead to false interpretation of these signatures. PRINCIPAL FINDINGS: A method was developed to test batches of a user-specified number of randomly chosen signatures in patient microarray datasets. The percentage of random generated signatures yielding prognostic value was assessed using ROC analysis by calculating the area under the curve (AUC in six public available cancer patient microarray datasets. We found that a signature consisting of randomly selected genes has an average 10% chance of reaching significance when assessed in a single dataset, but can range from 1% to ∼40% depending on the dataset in question. Increasing the number of validation datasets markedly reduces this number. CONCLUSIONS: We have shown that the use of an arbitrary cut-off value for evaluation of signature significance is not suitable for this type of research, but should be defined for each dataset separately. Our method can be used to establish and evaluate signature performance of any derived gene signature in a dataset by comparing its performance to thousands of randomly generated signatures. It will be of most interest for cases where few data are available and testing in multiple datasets is limited.

  11. Interactive Light Stimulus Generation with High Performance Real-Time Image Processing and Simple Scripting

    Directory of Open Access Journals (Sweden)

    László Szécsi

    2017-12-01

    Full Text Available Light stimulation with precise and complex spatial and temporal modulation is demanded by a series of research fields like visual neuroscience, optogenetics, ophthalmology, and visual psychophysics. We developed a user-friendly and flexible stimulus generating framework (GEARS GPU-based Eye And Retina Stimulation Software, which offers access to GPU computing power, and allows interactive modification of stimulus parameters during experiments. Furthermore, it has built-in support for driving external equipment, as well as for synchronization tasks, via USB ports. The use of GEARS does not require elaborate programming skills. The necessary scripting is visually aided by an intuitive interface, while the details of the underlying software and hardware components remain hidden. Internally, the software is a C++/Python hybrid using OpenGL graphics. Computations are performed on the GPU, and are defined in the GLSL shading language. However, all GPU settings, including the GPU shader programs, are automatically generated by GEARS. This is configured through a method encountered in game programming, which allows high flexibility: stimuli are straightforwardly composed using a broad library of basic components. Stimulus rendering is implemented solely in C++, therefore intermediary libraries for interfacing could be omitted. This enables the program to perform computationally demanding tasks like en-masse random number generation or real-time image processing by local and global operations.

  12. Interactive Light Stimulus Generation with High Performance Real-Time Image Processing and Simple Scripting.

    Science.gov (United States)

    Szécsi, László; Kacsó, Ágota; Zeck, Günther; Hantz, Péter

    2017-01-01

    Light stimulation with precise and complex spatial and temporal modulation is demanded by a series of research fields like visual neuroscience, optogenetics, ophthalmology, and visual psychophysics. We developed a user-friendly and flexible stimulus generating framework (GEARS GPU-based Eye And Retina Stimulation Software), which offers access to GPU computing power, and allows interactive modification of stimulus parameters during experiments. Furthermore, it has built-in support for driving external equipment, as well as for synchronization tasks, via USB ports. The use of GEARS does not require elaborate programming skills. The necessary scripting is visually aided by an intuitive interface, while the details of the underlying software and hardware components remain hidden. Internally, the software is a C++/Python hybrid using OpenGL graphics. Computations are performed on the GPU, and are defined in the GLSL shading language. However, all GPU settings, including the GPU shader programs, are automatically generated by GEARS. This is configured through a method encountered in game programming, which allows high flexibility: stimuli are straightforwardly composed using a broad library of basic components. Stimulus rendering is implemented solely in C++, therefore intermediary libraries for interfacing could be omitted. This enables the program to perform computationally demanding tasks like en-masse random number generation or real-time image processing by local and global operations.

  13. Skin and scales of teleost fish: Simple structure but high performance and multiple functions

    Science.gov (United States)

    Vernerey, Franck J.; Barthelat, Francois

    2014-08-01

    Natural and man-made structural materials perform similar functions such as structural support or protection. Therefore they rely on the same types of properties: strength, robustness, lightweight. Nature can therefore provide a significant source of inspiration for new and alternative engineering designs. We report here some results regarding a very common, yet largely unknown, type of biological material: fish skin. Within a thin, flexible and lightweight layer, fish skins display a variety of strain stiffening and stabilizing mechanisms which promote multiple functions such as protection, robustness and swimming efficiency. We particularly discuss four important features pertaining to scaled skins: (a) a strongly elastic tensile behavior that is independent from the presence of rigid scales, (b) a compressive response that prevents buckling and wrinkling instabilities, which are usually predominant for thin membranes, (c) a bending response that displays nonlinear stiffening mechanisms arising from geometric constraints between neighboring scales and (d) a robust structure that preserves the above characteristics upon the loss or damage of structural elements. These important properties make fish skin an attractive model for the development of very thin and flexible armors and protective layers, especially when combined with the high penetration resistance of individual scales. Scaled structures inspired by fish skin could find applications in ultra-light and flexible armor systems, flexible electronics or the design of smart and adaptive morphing structures for aerospace vehicles.

  14. Electrospray-deposition of graphene electrodes: a simple technique to build high-performance supercapacitors.

    Science.gov (United States)

    Tang, Huaichao; Yang, Cheng; Lin, Ziyin; Yang, Quanhong; Kang, Feiyu; Wong, Ching Ping

    2015-05-28

    Here we report an electrostatic spray deposition method to prepare three-dimensional porous graphene electrodes for supercapacitor applications. The symmetric supercapacitor exhibits excellent specific capacitance (366 F g(-1) at 1 A g(-1) in 6 M KOH) and long cycle life (108% capacitance retention up to 40 000 cycles). Moreover, the energy densities of the organic and aqueous electrolyte based supercapacitors reach 22.9 and 8.1 Wh kg(-1) when the power densities are 119.2 and 15.4 kW kg(-1), respectively. Compared with the previously reported graphene based supercapacitors, the improved properties could be attributed to the excellent three-dimensional open porous electrode structure, which is favorable for the ion diffusion and electron transport. In addition, this method provides a simple electrode-fabrication route without the involvement of conducting additives and binders. It may find vast applications in thin and miniaturized energy storage scenarios.

  15. Simple arithmetic: not so simple for highly math anxious individuals.

    Science.gov (United States)

    Chang, Hyesang; Sprute, Lisa; Maloney, Erin A; Beilock, Sian L; Berman, Marc G

    2017-12-01

    Fluency with simple arithmetic, typically achieved in early elementary school, is thought to be one of the building blocks of mathematical competence. Behavioral studies with adults indicate that math anxiety (feelings of tension or apprehension about math) is associated with poor performance on cognitively demanding math problems. However, it remains unclear whether there are fundamental differences in how high and low math anxious individuals approach overlearned simple arithmetic problems that are less reliant on cognitive control. The current study used functional magnetic resonance imaging to examine the neural correlates of simple arithmetic performance across high and low math anxious individuals. We implemented a partial least squares analysis, a data-driven, multivariate analysis method to measure distributed patterns of whole-brain activity associated with performance. Despite overall high simple arithmetic performance across high and low math anxious individuals, performance was differentially dependent on the fronto-parietal attentional network as a function of math anxiety. Specifically, low-compared to high-math anxious individuals perform better when they activate this network less-a potential indication of more automatic problem-solving. These findings suggest that low and high math anxious individuals approach even the most fundamental math problems differently. © The Author (2017). Published by Oxford University Press.

  16. High-performance beam steering using electrowetting-driven liquid prism fabricated by a simple dip-coating method

    Energy Technology Data Exchange (ETDEWEB)

    Enrico Clement, Carlos; Park, Sung-Yong, E-mail: mpeps@nus.edu.sg [Department of Mechanical Engineering, National University of Singapore, Block EA, #07-08, 9 Engineering Drive 1, 117576 (Singapore)

    2016-05-09

    A high degree of beam steering is demonstrated using an electrowetting-driven liquid prism. While prism devices have typically relied on complex and expensive laboratory setups, such as high-vacuum facilities for fabrication of dielectric layers, this work utilizes a simple dip-coating method to provide an ion gel layer as a dielectric, offering 2 or 3 orders higher specific capacitance (c ≈ 10 μF/cm{sup 2}) than that of conventional dielectrics. Analytical studies present the effects of liquid selection and arrangement on overall prism performance. For experimental demonstrations of high-performance beam steering, we not only selected two immiscible liquids of water and 1-bromonaphthalene (1-BN) oil which provide the large refractive index difference (n{sub water} = 1.33 and n{sub 1-BN} = 1.65 at λ = 532 nm) between them, but also utilized a double-stacked prism configuration which increases the number of interfaces for incoming light to be steered. At a prism apex angle of φ = 27°, we were able to achieve significantly large beam steering of up to β = 19.06°, which is the highest beam steering performance ever demonstrated using electrowetting technology.

  17. Simple, rapid, and environmentally friendly method for the separation of isoflavones using ultra-high performance supercritical fluid chromatography.

    Science.gov (United States)

    Wu, Wenjie; Zhang, Yuan; Wu, Hanqiu; Zhou, Weie; Cheng, Yan; Li, Hongna; Zhang, Chuanbin; Li, Lulu; Huang, Ying; Zhang, Feng

    2017-07-01

    Isoflavones are natural substances that exhibit hormone-like pharmacological activities. The separation of isoflavones remains an analytical challenge because of their similar structures. We show that ultra-high performance supercritical fluid chromatography can be an appropriate tool to achieve the fast separation of 12 common dietary isoflavones. Among the five tested columns the Torus DEA column was found to be the most effective column for the separation of these isoflavones. The impact of individual parameters on the retention time and separation factor was evaluated. These parameters were optimized to develop a simple, rapid, and green method for the separation of the 12 target analytes. It only took 12.91 min using gradient elution with methanol as an organic modifier and formic acid as an additive. These isoflavones were determined with limit of quantitation ranging from 0.10 to 0.50 μg/mL, which was sufficient for reliable determination of various matrixes. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Simple and sensitive high performance liquid chromatographic method for the simultaneous quantitation of the phenylalanine in human plasma

    Directory of Open Access Journals (Sweden)

    Hossein Danafar

    2015-09-01

    Full Text Available Phenylalanine (Phe is the most reliable indicator for the diagnosis of phenylketonuria (PKU. The purpose of this study is to establish a reliable and quick method for the assignment of Phe in peripheral capillary blood from newborns and children by high performance liquid chromatography with ultraviolet detection (HPLC-UV. PKU is an inborn error of metabolism characterized by the inability of the body to use Phe. A rapid and sensitive high performance liquid chromatographic (HPLC method has been developed for determination of Phe in plasma. The method uses a protein precipitation step with sulfosalicilic acid for sample preparation by separation on a Nova-pack C18 column using sodium acetate buffer and acetonitrile (94: 6 v/v adjusted to pH 6.5 with glacial acetic acid. The eluted peaks detected by a UV detector was set at wavelength of 215 nm. The method was validated in the range of Phe concentrations from 0.1 to 20 µg/ml. The limits of detection (LOD and quantitation (LOQ of the method were 0.05 and 0.1 µg/ml, respectively. The average drug recovery from plasma was 88.60 percent throughout the linear concentration range., with the average within-run and between-run accuracy values of 103.3 and 115.350, respectively. The method is quick, easy, very steady and precise for the screen, assignment, and evaluation of Phe in human plasma by HPLC, which is particularly a useful way for screening and diagnosis of PKU and monitoring of a diet therapy.

  19. A simple high-performance liquid chromatography for the determination of linezolid in human plasma and saliva.

    Science.gov (United States)

    Hara, Shuuji; Uchiyama, Masanobu; Yoshinari, Masami; Matsumoto, Taichi; Jimi, Shiro; Togawa, Atsushi; Takata, Tohru; Takamatsu, Yasushi

    2015-09-01

    Linezolid is an antimicrobial agent for the treatment of multiresistant Gram-positive infections. A practical high-performance liquid chromatography method was developed for the determination of linezolid in human plasma and saliva. Linezolid and an internal standard (o-ethoxybenzamide) were extracted from plasma and saliva with ethyl acetate and analyzed on a Capcell Pak C18 MG column with UV detection at 254 nm. The calibration curve was linear through the range 0.5-50 µg/mL using a 200 μL sample volume. The intra- and interday precisions were all plasma and 5.60% for saliva. The accuracies ranged from 98.8 to 110% for both matrices. The mean recoveries of linezolid were 80.8% for plasma and 79.0% for saliva. This method was used to determine the plasma and saliva concentrations of linezolid in healthy volunteers who were orally administered a 600 mg dose of linezolid. Our liquid-liquid extraction procedure is easy and requires a small volume of plasma or saliva (200 μL). This small volume can be advantageous in clinical pharmacokinetic studies, especially if children participate. Copyright © 2015 John Wiley & Sons, Ltd.

  20. An innovative, simple, fast, and less toxic high-performance liquid chromatographic method for determination of prednisone in capsules

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    Pedro Henrique Reis da Silva

    2017-06-01

    Full Text Available ABSTRACT Prednisone is an anti-inflammatory steroid drug widely used in clinical practice. However, no high-performance liquid chromatographic (HPLC method has been described in the literature for the determination of prednisone in capsules until now. Thus, an HPLC method was developed using a C18 (250x4.0, 5 µm column, with methanol:water (70:30 as mobile phase at a flow rate of 1 mL/min and detection at 240 nm. The developed method was validated following current Brazilian legislation. Additionally, linearity was assessed by evaluating the assumptions of normality, homoscedasticity, and independency of residuals, and the fit to the linear model. The method showed linearity (r2>0.99 over the range of 14.0-26.0 µg/mL, selectivity, precision (RSD<2.0%, robustness, and accuracy (average recovery of 100.05%. The chromatographic procedure was applied for assay and uniformity content determination of three different batches of prednisone capsules, showing to be suitable for their quality control.

  1. Monoclonal antibody heterogeneity analysis and deamidation monitoring with high-performance cation-exchange chromatofocusing using simple, two component buffer systems.

    Science.gov (United States)

    Kang, Xuezhen; Kutzko, Joseph P; Hayes, Michael L; Frey, Douglas D

    2013-03-29

    The use of either a polyampholyte buffer or a simple buffer system for the high-performance cation-exchange chromatofocusing of monoclonal antibodies is demonstrated for the case where the pH gradient is produced entirely inside the column and with no external mixing of buffers. The simple buffer system used was composed of two buffering species, one which becomes adsorbed onto the column packing and one which does not adsorb, together with an adsorbed ion that does not participate in acid-base equilibrium. The method which employs the simple buffer system is capable of producing a gradual pH gradient in the neutral to acidic pH range that can be adjusted by proper selection of the starting and ending pH values for the gradient as well as the buffering species concentration, pKa, and molecular size. By using this approach, variants of representative monoclonal antibodies with isoelectric points of 7.0 or less were separated with high resolution so that the approach can serve as a complementary alternative to isoelectric focusing for characterizing a monoclonal antibody based on differences in the isoelectric points of the variants present. Because the simple buffer system used eliminates the use of polyampholytes, the method is suitable for antibody heterogeneity analysis coupled with mass spectrometry. The method can also be used at the preparative scale to collect highly purified isoelectric variants of an antibody for further study. To illustrate this, a single isoelectric point variant of a monoclonal antibody was collected and used for a stability study under forced deamidation conditions. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. A Simple and High Performing Rate Control Initialization Method for H.264 AVC Coding Based on Motion Vector Map and Spatial Complexity at Low Bitrate

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    Yalin Wu

    2014-01-01

    Full Text Available The temporal complexity of video sequences can be characterized by motion vector map which consists of motion vectors of each macroblock (MB. In order to obtain the optimal initial QP (quantization parameter for the various video sequences which have different spatial and temporal complexities, this paper proposes a simple and high performance initial QP determining method based on motion vector map and temporal complexity to decide an initial QP in given target bit rate. The proposed algorithm produces the reconstructed video sequences with outstanding and stable quality. For any video sequences, the initial QP can be easily determined from matrices by target bit rate and mapped spatial complexity using proposed mapping method. Experimental results show that the proposed algorithm can show more outstanding objective and subjective performance than other conventional determining methods.

  3. Simple and sensitive monitoring of sulfonamide veterinary residues in milk by stir bar sorptive extraction based on monolithic material and high performance liquid chromatography analysis.

    Science.gov (United States)

    Huang, Xiaojia; Qiu, Ningning; Yuan, Dongxing

    2009-11-13

    A simple, rapid, and sensitive method for the quantitative monitoring of five sulfonamide antibacterial residues (SAs) in milk was developed by stir bar sorptive extraction (SBSE) coupling to high performance liquid chromatography with diode array detection. The analytes were concentrated by SBSE based on poly (vinylimidazole-divinylbenzene) monolithic material as coating. The extraction procedure was very simple, milk was diluted with water then directly sorptive extraction without elimination of fats and protein in samples was required. To achieve optimum extraction performance for SAs, several parameters, including extraction and desorption time, desorption solvent, ionic strength and pH value of sample matrix were investigated. Under the optimized experimental conditions, low detection limits (S/N=3) quantification limits (S/N=10) of the proposed method for the target compounds were achieved within the range of 1.30-7.90 ng/mL and 4.29-26.3 ng/mL from spiked milk, respectively. Good linearities were obtained for SAs with the correlation coefficients (R(2)) above 0.996. Finally, the proposed method was successfully applied to the determination of SAs compounds in different milk samples and satisfied recoveries of spiked target compounds in real samples were obtained.

  4. Development and Validation of a Simple High Performance Liquid Chromatography/UV Method for Simultaneous Determination of Urinary Uric Acid, Hypoxanthine, and Creatinine in Human Urine

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    Nimanthi Wijemanne

    2018-01-01

    Full Text Available Uric acid and hypoxanthine are produced in the catabolism of purine. Abnormal urinary levels of these products are associated with many diseases and therefore it is necessary to have a simple and rapid method to detect them. Hence, we report a simple reverse phase high performance liquid chromatography (HPLC/UV technique, developed and validated for simultaneous analysis of uric acid, hypoxanthine, and creatinine in human urine. Urine was diluted appropriately and eluted with C-18 column 100 mm × 4.6 mm with a C-18 precolumn 25 mm × 4.6 mm in series. Potassium phosphate buffer (20 mM, pH 7.25 at a flow rate of 0.40 mL/min was employed as the solvent and peaks were detected at 235 nm. Tyrosine was used as the internal standard. The experimental conditions offered a good separation of analytes without interference of endogenous substances. The calibration curves were linear for all test compounds with a regression coefficient, r2>0.99. Uric acid, creatinine, tyrosine, and hypoxanthine were eluted at 5.2, 6.1, 7.2, and 8.3 min, respectively. Intraday and interday variability were less than 4.6% for all the analytes investigated and the recovery ranged from 98 to 102%. The proposed HPLC procedure is a simple, rapid, and low cost method with high accuracy with minimum use of organic solvents. This method was successfully applied for the determination of creatinine, hypoxanthine, and uric acid in human urine.

  5. A Simple and Rapid Determination of ATP, ADP and AMP Concentrations in Pericarp Tissue of Litchi Fruit by High Performance Liquid Chromatography

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    Weibo Jiang

    2006-01-01

    Full Text Available A simple and rapid method using high performance liquid chromatography (HPLC was developed to determine levels of adenosine triphosphate (ATP, adenosine diphosphate (ADP and adenosine monophosphate (AMP in litchi fruit pericarp tissue. This HPLC method used acetonitrile gradient elution and shortened the time required for determinations of adenosine phosphates. This analysis exhibited good repeatability (coefficients of variation 1.28–1.80 % and recovery rate (94.7–97.1 %. The correlation coefficients of ATP, ADP and AMP with their peak areas at a range of 0–80 ng were 0.9946, 0.9994 and 0.9974, respectively. This method was applied to determine levels of adenosine phosphates in pericarp tissue of litchi fruit at harvest. There were 27.4 μg/g of ATP, 35.4 μg/g of ADP and 7.9 μg/g of AMP on a fresh mass basis.

  6. Molecularly imprinted polymer cartridges coupled on-line with high performance liquid chromatography for simple and rapid analysis of dextromethorphan in human plasma samples.

    Science.gov (United States)

    Moein, Mohammad Mahdi; Javanbakht, Mehran; Akbari-Adergani, Behrouz

    2011-04-01

    In this paper, a novel method is described for automated determination of dextromethorphan in biological fluids using molecularly imprinted solid-phase extraction (MISPE) as a sample clean-up technique combined with high performance liquid chromatography (HPLC). The water-compatible molecularly imprinted polymers (MIPs) were prepared using methacrylic acid as functional monomer, ethylene glycol dimethacrylate as cross-linker, chloroform as porogen and dextromethorphan as template molecule. These imprinted polymers were used as solid-phase extraction sorbent for the extraction of dextromethorphan from human plasma samples. Various parameters affecting the extraction efficiency of the MIP cartridges were evaluated. The high selectivity of the sorbent coupled to the high performance liquid chromatographic system permitted a simple and rapid analysis of this drug in plasma samples with limits of detection (LOD) and quantification (LOQ) of 0.12 ng/mL and 0.35 ng/mL, respectively. The MIP selectivity was evaluated by analyzing of the dextromethorphan in presence of several substances with similar molecular structures and properties. Results from the HPLC analyses showed that the recoveries of dextromethorphan using MIP cartridges from human plasma samples in the range of 1-50 ng/mL were higher than 87%. Copyright © 2011 Elsevier B.V. All rights reserved.

  7. Simple-design ultra-low phase noise microwave frequency synthesizers for high-performing Cs and Rb vapor-cell atomic clocks

    Energy Technology Data Exchange (ETDEWEB)

    François, B. [FEMTO-ST, CNRS, Université de Franche-Comté, 26 chemin de l’Epitaphe, 25030 Besançon (France); INRIM, Strada delle Cacce 91, 10135 Torino (Italy); Calosso, C. E.; Micalizio, S. [INRIM, Strada delle Cacce 91, 10135 Torino (Italy); Abdel Hafiz, M.; Boudot, R. [FEMTO-ST, CNRS, Université de Franche-Comté, 26 chemin de l’Epitaphe, 25030 Besançon (France)

    2015-09-15

    We report on the development and characterization of novel 4.596 GHz and 6.834 GHz microwave frequency synthesizers devoted to be used as local oscillators in high-performance Cs and Rb vapor-cell atomic clocks. The key element of the synthesizers is a custom module that integrates a high spectral purity 100 MHz oven controlled quartz crystal oscillator frequency-multiplied to 1.6 GHz with minor excess noise. Frequency multiplication, division, and mixing stages are then implemented to generate the exact output atomic resonance frequencies. Absolute phase noise performances of the output 4.596 GHz signal are measured to be −109 and −141 dB rad{sup 2}/Hz at 100 Hz and 10 kHz Fourier frequencies, respectively. The phase noise of the 6.834 GHz signal is −105 and −138 dB rad{sup 2}/Hz at 100 Hz and 10 kHz offset frequencies, respectively. The performances of the synthesis chains contribute to the atomic clock short term fractional frequency stability at a level of 3.1 × 10{sup −14} for the Cs cell clock and 2 × 10{sup −14} for the Rb clock at 1 s averaging time. This value is comparable with the clock shot noise limit. We describe the residual phase noise measurements of key components and stages to identify the main limitations of the synthesis chains. The residual frequency stability of synthesis chains is measured to be at the 10{sup −15} level for 1 s integration time. Relevant advantages of the synthesis design, using only commercially available components, are to combine excellent phase noise performances, simple-architecture, low-cost, and to be easily customized for signal output generation at 4.596 GHz or 6.834 GHz for applications to Cs or Rb vapor-cell frequency standards.

  8. A simple high-performance liquid chromatographic method for the estimation of boswellic acids from the market formulations containing Boswellia serrata extract.

    Science.gov (United States)

    Shah, Shailesh A; Rathod, Ishwarsinh S; Suhagia, Bhanubhai N; Pandya, Saurabh S; Parmar, Vijay K

    2008-09-01

    A simple, rapid, and reproducible reverse-phase high-performance liquid chromatographic method is developed for the estimation of boswellic acids, the active constituents in Boswellia serrata oleo-gum resin. The chromatographic separation is performed using a mobile phase consisting of acetonitrile-water (90:10, % v/v) adjusted to pH 4 with glacial acetic acid on a Kromasil 100 C18 analytical column with flow rate of 2.0 mL/min and detection at 260 nm. The elution times are 4.30 and 7.11 min for 11-keto beta-boswellic acid (11-KBA) and 3-acetyl 11-keto beta-boswellic acid (A-11-KBA), respectively. The calibration curve is linear in the 11.66-58.30 microg/mL and 6.50-32.50 microg/mL range for 11-KBA and A-11-KBA, respectively. The limits of detection are 2.33 microg/mL and 1.30 microg/mL for 11-KBA and A-11-KBA, respectively. The mean recoveries are 98.24% to 104.17% and 94.12% to 105.92% for 11-KBA and A-11-KBA, respectively. The inter- and intra-day variation coefficients are less than 5%. The present method is successfully applied for the estimation of boswellic acids from the market formulations containing Boswellia serrata extract.

  9. A simple reversed phase high-performance liquid chromatography (RP-HPLC method for determination of curcumin in aqueous humor of rabbit

    Directory of Open Access Journals (Sweden)

    Akhilesh Mishra

    2014-01-01

    Full Text Available This article describes a simple and rapid method for determination of curcumin (diferuloylmethane in aqueous humor of rabbit using high-performance liquid chromatography (HPLC. Analysis was performed using a C-18 column (250 × 4.6 mm, 5 μ luna by isocratic elution with a mobile phase containing 25 mM potassium dihydrogen orthophosphate (pH 3.5: Acetonitrile (40:60 and detection at 424 nm using a photodiode array (PDA detector for curcumin. The regression data for curcumin showed a good linear relationship with r 2 > 0.998 over the concentration range of 0.1-10 μg ml−1 . Relative standard deviations (RSD for the intraday and interday coefficient of variations for the assay were less than 5.0 and 8.5, respectively. The recovery of the method was between 79.8-83.6%. The quantification limit of the method for curcumin was 0.01 μg ml−1 . This method has good accuracy, precision, and quantitation limit. It is also concluded that the method is useful for measuring very low curcumin concentrations in aqueous humor.

  10. A simple and rapid ultra-high-performance liquid chromatography-tandem mass spectrometry method to determine plasma biotin in hemodialysis patients.

    Science.gov (United States)

    Yagi, Shigeaki; Nishizawa, Manabu; Ando, Itiro; Oguma, Shiro; Sato, Emiko; Imai, Yutaka; Fujiwara, Masako

    2016-08-01

    A simple, rapid, and selective method for determination of plasma biotin was developed using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). After single-step protein precipitation with methanol, biotin and stable isotope-labeled biotin as an internal standard (IS) were chromatographed on a pentafluorophenyl stationary-phase column (2.1 × 100 mm, 2.7 μm) under isocratic conditions using 10 mm ammonium formate-acetonitrile (93:7, v/v) at a flow rate of 0.6 mL/min. The total chromatographic runtime was 5 min for each injection. Detection was performed in a positive electrospray ionization mode by monitoring selected ion transitions at m/z 245.1/227.0 and 249.1/231.0 for biotin and the IS, respectively. The calibration curve was linear in the range of 0.05-2 ng/mL using 300 μL of plasma. The intra- and inter-day precisions were all biotin concentrations in hemodialysis patients. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  11. Simple and rapid method on High Performance Liquid Chromatography for simultaneous determination of benzylpenicillin potassium, streptomycin sulphate and related substances in Ascomicin – a veterinary use ointment

    Directory of Open Access Journals (Sweden)

    Neagu Maria

    2015-06-01

    Full Text Available A new simple, rapid, accurate and precise HighPerformance Liquid Chromatography (HPLC method for determination of benzylpenicillin potassium and streptomycin sulphate in Ascomicin ointment was developed and validated. The method can be used for the detection and quantification of known and unknown impurities and degradation products in this pharmaceutical product during routine analysis and also for stability studies in view of its capability to separate degradation products. The method was validated for accuracy, precision, specificity, robustness and quantification limits according to ICH Guidelines. The estimation of benzylpenicillin potassium and streptomycin sulphate was done by Waters HPLC 2695. The chromatographic conditions comprised a reverse-phased C18 column (5 µm particle size, 250 mm×4.6 mm i.d. with a mobile phase consisting of a mixture of solution in water containing 0.025 M of sodium phosphate dibasic and 0.02 of sodium hexansulfonate adjusted to pH 6.0 with 22.5 g/lsolution of phosphoric acid and acetonitrile in gradient elution. The flow rate was 0.8 ml/min. Standard curves were linear over the concentration range of 5.00 µg/ml to 5.00 mg/ml for streptomycin sulphate and 3.26 µg/ml to 3.26 mg/ml for benzylpenicillin potassium. Statistical analyses proved the method was precise, reproducible, selective, specific and accurate for analysis of benzylpenicillin potassium, streptomycin sulphate and related substances.

  12. A Simple Prelithiation Strategy To Build a High-Rate and Long-Life Lithium-Ion Battery with Improved Low-Temperature Performance.

    Science.gov (United States)

    Liu, Yao; Yang, Bingchang; Dong, Xiaoli; Wang, Yonggang; Xia, Yongyao

    2017-12-22

    Lithium-ion batteries (LIBs) are being used to power the commercial electric vehicles (EVs). However, the charge/discharge rate and life of current LIBs still cannot satisfy the further development of EVs. Furthermore, the poor low-temperature performance of LIBs limits their application in cold climates and high altitude areas. Herein, a simple prelithiation method is developed to fabricate a new LIB. In this strategy, a Li 3 V 2 (PO 4 ) 3 cathode and a pristine hard carbon anode are used to form a primary cell, and the initial Li + extraction from Li 3 V 2 (PO 4 ) 3 is used to prelithiate the hard carbon. Then, the self-formed Li 2 V 2 (PO 4 ) 3 cathode and prelithiated hard carbon anode are used to form a 4 V LIB. The LIB exhibits a maximum energy density of 208.3 Wh kg -1 , a maximum power density of 8291 W kg -1 and a long life of 2000 cycles. When operated at -40 °C, the LIB can keep 67 % capacity of room temperature, which is much better than conventional LIBs. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. A simple, sensitive and rapid isocratic reversed-phase high-performance liquid chromatography method for determination and stability study of curcumin in pharmaceutical samples

    Science.gov (United States)

    Amanolahi, Farjad; Mohammadi, Ali; Kazemi Oskuee, Reza; Nassirli, Hooriyeh; Malaekeh-Nikouei, Bizhan

    2017-01-01

    Objective: This study was designed to develop and validate a new reversed-phase high-performance liquid chromatography (RP-HPLC) method based on Q2 (R1) International Conference on Harmonization (ICH) guideline for determination of curcumin in pharmaceutical samples. Materials and Methods: The HPLC instrument method was optimized with isocratic elution with acetonitrile: ammonium acetate (45:55, v/v, pH 3.5), C18 column (150 mm×4.6 mm×5 µm particle size) and a flow rate of 1 ml/min in ambient condition and total retention time of 17 min. The volume of injection was set at 20 µl and detection was recorded at 425 nm. The robustness of the method was examined by changing the mobile phase composition, mobile phase pH, and flow rate. Results: The method was validated with respect to precision, accuracy and linearity in a concentration range of 2-100 µg/ml. The limit of detection (LOD) and limit of quantification (LOQ) were 0.25 and 0.5 µg/ml, respectively. The percentage of recovery was 98.9 to 100.5 with relative standard deviation (RSD) < 0.638%. Conclusion: The method was found to be simple, sensitive and rapid for determination of curcumin in pharmaceutical samples and had enough sensitivity to detect degradation product of curcumin produced under photolysis and hydrolysis stress condition. PMID:29062806

  14. Performance of n-γ pulse-shape discrimination with simple pile-up rejection at high γ-ray count rates

    International Nuclear Information System (INIS)

    Okuda, T.; Yamazaki, H.; Kawabata, M.; Kasagi, J.; Harada, H.

    1999-01-01

    The performance of n-γ pulse-shape discrimination for a liquid scintillation detector has been investigated for γ-ray count rates up to 50 kcps. A method in which the ratio of the total to partial charge in the anode pulse is directly measured has shown much improved quality of the pulse-shape discrimination when pile-up events are rejected; it can discriminate neutron events of 50 cps from γ-ray events of 29 kcps. The method with simple pile-up rejection has the advantage that only general purpose electronics are required

  15. Simple, high current, antimony ion source

    International Nuclear Information System (INIS)

    Sugiura, H.

    1979-01-01

    A simple metal ion source capable of producing a continuous, uncontaminated, high current beam of Sb ions is presented. It produced a total ion current of 200 μA at 1 kV extraction voltage. A discharge occurred in the source at a pressure of 6 x 10 -4 Torr. The ion current extracted from the source increased with the 3/2 power of the extraction voltage. The perveance of the source and ion density in the plasma were 8 x 10 -9 and 1.8 x 10 11 cm -3 , respectively

  16. The simple and sensitive measurement of malondialdehyde in selected specimens of biological origin and some feed by reversed phase high performance liquid chromatography

    Czech Academy of Sciences Publication Activity Database

    Czauderna, M.; Kowalczyk, J.; Marounek, Milan

    2011-01-01

    Roč. 879, č. 23 (2011), s. 2251-2258 ISSN 1570-0232 Institutional research plan: CEZ:AV0Z50450515 Keywords : Malondialdehyde * 2,4-Dinitrophenylhydrazine * High performance liquid chromatography Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 2.888, year: 2011

  17. A simple, rapid and validated high-performance liquid chromatography method suitable for clinical measurements of human mercaptalbumin and non-mercaptalbumin.

    Science.gov (United States)

    Yasukawa, Keiko; Shimosawa, Tatsuo; Okubo, Shigeo; Yatomi, Yutaka

    2018-01-01

    Background Human mercaptalbumin and human non-mercaptalbumin have been reported as markers for various pathological conditions, such as kidney and liver diseases. These markers play important roles in redox regulations throughout the body. Despite the recognition of these markers in various pathophysiologic conditions, the measurements of human mercaptalbumin and non-mercaptalbumin have not been popular because of the technical complexity and long measurement time of conventional methods. Methods Based on previous reports, we explored the optimal analytical conditions for a high-performance liquid chromatography method using an anion-exchange column packed with a hydrophilic polyvinyl alcohol gel. The method was then validated using performance tests as well as measurements of various patients' serum samples. Results We successfully established a reliable high-performance liquid chromatography method with an analytical time of only 12 min per test. The repeatability (within-day variability) and reproducibility (day-to-day variability) were 0.30% and 0.27% (CV), respectively. A very good correlation was obtained with the results of the conventional method. Conclusions A practical method for the clinical measurement of human mercaptalbumin and non-mercaptalbumin was established. This high-performance liquid chromatography method is expected to be a powerful tool enabling the expansion of clinical usefulness and ensuring the elucidation of the roles of albumin in redox reactions throughout the human body.

  18. Simple O2 Plasma-Processed V2O5 as an Anode Buffer Layer for High-Performance Polymer Solar Cells

    DEFF Research Database (Denmark)

    Bao, Xichang; Zhu, Qianqian; Wang, Ting

    2015-01-01

    A simple O2 plasma processing method for preparation of a vanadium oxide (V2O5) anode buffer layer on indium tin oxide (ITO)-coated glass for polymer solar cells (PSCs) is reported. The V2O5 layer with high transmittance and good electrical and interfacial properties was prepared by spin coating...... the illumination of AM 1.5G (100 mW/cm2). Compared to that of the control device with PBDTTT-C:PC71BM as the active layer and PEDOT:PSS (PCE of 6.52%) and thermally annealed V2O5 (PCE of 6.27%) as the anode buffer layer, the PCE was improved by 15.6 and 20.2%, respectively, after the introduction of a V2O5 (O2...... plasma) anode buffer layer. The improved PCE is ascribed to the greatly improved fill factor and enhanced short-circuit current density of the devices, which benefited from the change in the work function of V2O5, a surface with many dangling bonds for better interfacial contact, and the excellent charge...

  19. Quantification of anthocyanins in commercial black currant juices by simple high-performance liquid chromatography. Investigation of their pH stability and antioxidative potency

    DEFF Research Database (Denmark)

    Nielsen, Inge Lise F.; Ravn-Haren, Gitte; Magnussen, Eva Loftin

    2003-01-01

    (HPLC) method. The method was validated, and quantification of anthocyanins in 13 commercially available black currant beverages was demonstrated. To optimize the handling of anthocyanin-containing samples, the pH-dependent stability of the anthocyanins was investigated. Four anthocyanins were incubated......Quantitative determinations of the four black currant anthocyanins, cyanidin 3-O-beta-glucoside, cyanidin 3-O-beta-rutinoside, delphinidin 3-O-beta-glucoside, and delphinidin 3-O-beta-rutinoside, were achieved in black currant juices by a rapid and sensitive high-performance liquid chromatographic...

  20. A rapid and simple determination of A77 1726 in human serum by high-performance liquid chromatography and its application for optimization of leflunomide therapy

    NARCIS (Netherlands)

    van Roon, EN; Yska, JP; Raemaekers, J; Jansen, TLTA; van Wanrooy, M; Brouwers, JRBJ

    2004-01-01

    Leflunomide is a disease-modifying antirheumatic drug, which is bioactivated by fort-nation of A77 1726. In this study a rapid and simple quantitative assay using a reversed phase HPLC-UV method is validated for detection of A77 1726 in human serum. The HPLC-UV method uses a mobile phase consisting

  1. A simple and rapid method for the determination of taxol produced by fungal endophytes from medicinal plants using high performance thin layer chromatography.

    Science.gov (United States)

    Gangadevi, V; Muthumary, J

    2008-01-01

    Taxol is an important anticancer drug used widely in the clinical field. In this study, some endophytic fungi were isolated from selected medicinal plants, and were screened for their potential in the production of taxol, using a rapid separation technique of high performance thin layer chromatography (HPTLC). Of the 20 screened fungi, only 13 fungal species produced taxol in the artificial culture medium. The results of HPTLC showed that the 13 fungal species had identical ultraviolet (UV) characteristics, positive reactivity with a spray reagent, yielding a blue spot, which turned to dark gray after 24 hours, and had Rf values identical to that of the authentic taxol. The amount of taxol was also quantified by comparing the peak area and the peak height of the fungal samples with those of authentic taxol.

  2. Simple measurement of isepamicin, a new aminoglycoside antibiotic, in guinea pig and human plasma, using high-performance liquid chromatography with ultraviolet detection

    International Nuclear Information System (INIS)

    Dionisotti, S.; Bamonte, F.; Scaglione, F.; Ongini, E.

    1991-01-01

    Isepamicin, the 1-N-(S-alpha-hydroxy-beta-aminopropionyl) derivative of gentamicin B, is a new aminoglycoside antibiotic, which not only has most of the properties of amikacin but also is effective against several amikacin-resistant strains of bacteria. The drug was assayed in guinea-pig and human plasma with a high-performance liquid chromatographic procedure using precolumn derivatization with 1-fluoro-2,4-dinitrobenzene and ultraviolet detection. Linearity was established over the range 0.5-40 micrograms/ml using 50 microliters of plasma. Accuracy has a mean relative error of less than 3% and precision a mean coefficient of variation of 5%. Isepamicin was determined without interference from plasma constituents or other drugs commonly prescribed during aminoglycoside therapy. This procedure correlates well with radioimmunoassay and can be used either in experimental studies or therapeutic monitoring of plasma levels

  3. Molecularly imprinted polymer cartridges coupled to high performance liquid chromatography (HPLC-UV) for simple and rapid analysis of fenthion in olive oil.

    Science.gov (United States)

    Bakas, Idriss; Ben Oujji, Najwa; Istamboulié, Georges; Piletsky, Sergey; Piletska, Elena; Ait-Addi, Elhabib; Ait-Ichou, Ihya; Noguer, Thierry; Rouillon, Régis

    2014-07-01

    A combination of molecular modelling and a screening of the library of non-imprinted polymers (NIPs) was used to identify acrylamide as a functional monomer with high affinity towards fenthion, organophosphate insecticide, which is frequently used in the treatment of olives. A good correlation was found between the screening tests and modelling of monomer-template interactions performed using a computational approach. Acrylamide-based molecularly imprinted polymer (MIP) and non-imprinted polymer (NIP) were thermally synthesised in dimethyl formamide (porogen) using ethylene glycol dimethacrylate as a cross-linker and 1,1-azo-bis (isobutyronitrile) as an initiator. The chemical and physical properties of the prepared polymers were characterised. The binding of fenthion by the polymers was studied using solvents with different polarities. The developed MIP showed a high selectivity towards fenthion, compared to other organophosphates (dimethoate, methidathion malalthion), and allowed extraction of fenthion from olive oil samples with a recovery rate of about 96%. The extraction of fenthion using MIPs was much more effective than traditional C18 reverse-phase solid phase extraction and allowed to achieve a low detection limit (LOD) (5 µg L(-1)). Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Determination and validation of a simple high-performance liquid chromatographic method for simultaneous assay of iprodione and vinclozolin in human urine.

    Science.gov (United States)

    Carlucci, Giuseppe; Pasquale, Dorina Di; Ruggieri, Fabrizio; Mazzeo, Pietro

    2005-12-15

    A method based on solid-phase extraction (SPE) and high-performance liquid chromatography (HPLC) was developed for the simultaneous determination of 3-(3,5-diclorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione (vinclozolin) and 3-(3,5-diclorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide (iprodione) in human urine. Urine samples containing vinclozolin and iprodione were collected by solid phase extraction using C(18) cartridges. The chromatographic separation was achieved on a Spherisorb ODS2 (250 mm x 4.6 mm, 5 microm) column with an isocratic mobile phase of acetonitrile-water (60:40, v/v). Detection was UV absorbance at 220 nm. The calibration graphs were linear from 30 to 1000 ng/mL for the two fungicides. Intra- and inter-day R.S.D. did not exceed 2.9%. The quantitation limit was 50 ng/mL for vinclozolin and 30 ng/mL for iprodione, respectively.

  5. Determination of Ten Corticosteroids in Illegal Cosmetic Products by a Simple, Rapid, and High-Performance LC-MS/MS Method

    Directory of Open Access Journals (Sweden)

    Vita Giaccone

    2017-01-01

    Full Text Available The aim of our present work was the development of a rapid high-performance liquid chromatography method with electrospray ionization and tandem mass spectrometry detection (LC-ESI-MS/MS for the determination of several corticosteroids in cosmetic products. Corticosteroids are suspected to be illegally added in cosmetic preparations in order to enhance the curative effect against some skin diseases. Sample preparation step consists in a single extraction with acetonitrile followed by centrifugation and filtration. The compounds were separated by reversed-phase chromatography with water and acetonitrile (both with 0.1% formic acid gradient elution and detected by ESI-MS positive and negative ionization mode. The method was validated at the validation level of 0.1 mg kg−1. Linearity was studied in the 5–250 μg L−1 range and linear coefficients (r2 were all over 0.99. The accuracy and precision of the method were satisfactory. The LOD ranged from 0.085 to 0.109 mg kg−1 and the LOQ from 0.102 to 0.121 mg kg−1. Mean recoveries for all the analytes were within the range 91.9–99.2%. The developed method is sensitive and useful for detection, quantification, and confirmation of these corticosteroids in cosmetic preparations and can be applied in the analysis of the suspected samples under investigation.

  6. A combined simple bubbling method with high performance liquid chromatography purification strategy, higher radiochemical yield and purity and faster preparation of carbon-11-raclopride.

    Science.gov (United States)

    Huang, Huacheng; Ning, Yanli; Zhang, Bucheng; Lou, Cen

    2015-01-01

    Carbon-11-raclopride (¹¹C-R) is a positron-emitting radiotracer successfully used for the study of cognitive control and widely applied in PET imaging. A simple automated preparation of ¹¹C-R by using the reaction of carbon-(11)-methyl triflate (¹¹C-MeOTF) or ¹¹C-methyl iodide (¹¹C-MeI) with demethylraclopride is described. Specifically we used a simple setup applied an additional "U" reaction vessel for ¹¹C-MeOTf compared with ¹¹C-MeI and assessed the influence of several solvents and of the amount of the percussor for ¹¹C-methylation of demethylraclopride by the bubbling method. The reversal of retention order between product and its precursor has been achieved for ¹¹C-R, enabling collection of the purified ¹¹C-R by using the HPLC column after shorter retention time. By the improved radiosynthesis and purification strategy, ¹¹C-R could be prepared with higher radiochemical yield than that of the previous studies. The yield for ¹¹C-MeOTf was 76% and for ¹¹C-CH3I >26% and with better radiochemical purity (>99% based on both ¹¹C-MeOTf and ¹¹C-MeI) as compared to the previously obtained purity of ¹¹C-R using HPLC method with acetonitrile as a part of mobile phase. Furthermore, by using ethanol as the organic modifier, residual solvent analysis prior to human injection could be avoided and ¹¹C-R could be injected directly following simple dilution and sterile filtration. Improved radiosynthesis and HPLC purification in combination with ethanol containing eluent, extremely shortened the time for preparation of ¹¹C-R, gave a higher radiochemical yield and purity for ¹¹C-R and can be used for multiple and faster synthesis of ¹¹C-R and probably for other ¹¹C-labeled radiopharmaceuticals.

  7. Development and validation of a simple high-performance liquid chromatography analytical method for simultaneous determination of phytosterols, cholesterol and squalene in parenteral lipid emulsions.

    Science.gov (United States)

    Novak, Ana; Gutiérrez-Zamora, Mercè; Domenech, Lluís; Suñé-Negre, Josep M; Miñarro, Montserrat; García-Montoya, Encarna; Llop, Josep M; Ticó, Josep R; Pérez-Lozano, Pilar

    2018-02-01

    A simple analytical method for simultaneous determination of phytosterols, cholesterol and squalene in lipid emulsions was developed owing to increased interest in their clinical effects. Method development was based on commonly used stationary (C 18 , C 8 and phenyl) and mobile phases (mixtures of acetonitrile, methanol and water) under isocratic conditions. Differences in stationary phases resulted in peak overlapping or coelution of different peaks. The best separation of all analyzed compounds was achieved on Zorbax Eclipse XDB C 8 (150 × 4.6 mm, 5 μm; Agilent) and ACN-H 2 O-MeOH, 80:19.5:0.5 (v/v/v). In order to achieve a shorter time of analysis, the method was further optimized and gradient separation was established. The optimized analytical method was validated and tested for routine use in lipid emulsion analyses. Copyright © 2017 John Wiley & Sons, Ltd.

  8. Investigation of grid performance using simple image quality tests

    Directory of Open Access Journals (Sweden)

    Dogan Bor

    2016-01-01

    Full Text Available Antiscatter grids improve the X-ray image contrast at a cost of patient radiation doses. The choice of appropriate grid or its removal requires a good knowledge of grid characteristics, especially for pediatric digital imaging. The aim of this work is to understand the relation between grid performance parameters and some numerical image quality metrics for digital radiological examinations. The grid parameters such as bucky factor (BF, selectivity (Σ, Contrast improvement factor (CIF, and signal-to-noise improvement factor (SIF were determined following the measurements of primary, scatter, and total radiations with a digital fluoroscopic system for the thicknesses of 5, 10, 15, 20, and 25 cm polymethyl methacrylate blocks at the tube voltages of 70, 90, and 120 kVp. Image contrast for low- and high-contrast objects and high-contrast spatial resolution were measured with simple phantoms using the same scatter thicknesses and tube voltages. BF and SIF values were also calculated from the images obtained with and without grids. The correlation coefficients between BF values obtained using two approaches (grid parameters and image quality metrics were in good agreement. Proposed approach provides a quick and practical way of estimating grid performance for different digital fluoroscopic examinations.

  9. Communication: Simple liquids' high-density viscosity

    Science.gov (United States)

    Costigliola, Lorenzo; Pedersen, Ulf R.; Heyes, David M.; Schrøder, Thomas B.; Dyre, Jeppe C.

    2018-02-01

    This paper argues that the viscosity of simple fluids at densities above that of the triple point is a specific function of temperature relative to the freezing temperature at the density in question. The proposed viscosity expression, which is arrived at in part by reference to the isomorph theory of systems with hidden scale invariance, describes computer simulations of the Lennard-Jones system as well as argon and methane experimental data and simulation results for an effective-pair-potential model of liquid sodium.

  10. Communication: Simple liquids' high-density viscosity.

    Science.gov (United States)

    Costigliola, Lorenzo; Pedersen, Ulf R; Heyes, David M; Schrøder, Thomas B; Dyre, Jeppe C

    2018-02-28

    This paper argues that the viscosity of simple fluids at densities above that of the triple point is a specific function of temperature relative to the freezing temperature at the density in question. The proposed viscosity expression, which is arrived at in part by reference to the isomorph theory of systems with hidden scale invariance, describes computer simulations of the Lennard-Jones system as well as argon and methane experimental data and simulation results for an effective-pair-potential model of liquid sodium.

  11. Graphene oxide quantum dot-derived nitrogen-enriched hybrid graphene nanosheets by simple photochemical doping for high-performance supercapacitors

    Science.gov (United States)

    Xu, Yongjie; Li, Xinyu; Hu, Guanghui; Wu, Ting; Luo, Yi; Sun, Lang; Tang, Tao; Wen, Jianfeng; Wang, Heng; Li, Ming

    2017-11-01

    Nitrogen-enriched graphene was fabricated via a facile strategy. Graphene oxide (GO) nanosheets and graphene oxide quantum dots (GQDs) were used as a structure-directing agent and in situ activating agent, respectively, after photoreduction under NH3 atmosphere. The combination of photoreduction and NH3 not only reduced GO and GQD composites (GO/GQDs) within a shorter duration but also doped a high level of nitrogen on the composites (NrGO/GQDs). The nitrogen content of NrGO/GQDs reached as high as 18.86 at% within 5 min of irradiation. Benefiting from the nitrogen-enriched GO/GQDs hybrid structure, GQDs effectively prevent the agglomeration of GO sheets and increased the numbers of ion channels in the material. Meanwhile, the high levels of nitrogen improved electrical conductivity and strengthened the binding energy between GQD and GO sheets. Compared with reduced GO and low nitrogen-doped reduced GO, NrGO/GQD electrodes exhibited better electrochemical characteristics with a high specific capacitance of 344 F g-1 at a current density of 0.25 A g-1. Moreover, the NrGO/GQD electrodes exhibited 82% capacitance retention after 3000 cycles at a current density of 0.8 A g-1 in 6 M KOH electrolyte. More importantly, the NrGO/GQD electrodes deliver a high energy density of 43 Wh kg-1 at a power density of 417 W kg-1 in 1 M Li2SO4 electrolyte. The nitrogen-doped graphene and corresponding supercapacitor presented in this study are novel materials with potential applications in advanced energy storage systems.

  12. A simple synthetic route of N-doped mesoporous carbon derived from casein extracted with cobalt ions for high rate performance supercapacitors

    International Nuclear Information System (INIS)

    Jia, Shaopei; Wang, Yanhui; Tian, Pengfei; Zhou, Shuyu; Cai, Haixia; Gao, Hongwei; Zang, Jianbing

    2017-01-01

    Highlights: •NMC is prepared by pyrolysis of cobalt-containing casein. •Cobalt-containing casein is extracted from the pure milk by cobalt ions. •The cobalt element increases the specific surface area and the N doping amount. •NMC exhibits high specific capacitance, high rate capability, and excellent cycling stability. -- Abstract: Nitrogen-doped mesoporous carbon (NMC) was synthesized via pyrolysis of cobalt-containing casein obtained by extraction from pure milk with the auxiliary of cobalt ions. The cobalt element in casein promoted specific surface area and N element doping amount of casein-derived porous carbon. The N-doped porous carbon obtained by carbonization at 800 °C (NPC-800) possessed a specific surface area of ∼886.7 m 2 g −1 , and the mesoporous size was centered at 2.7 and 7 nm. X-ray photoelectron spectroscopy analysis showed that the nitrogen content of NPC-800 was 3.29 at%. The NPC-800 was explored as a symmetric supercapacitor, which exhibited specific capacity of 380 F g −1 at a current density of 0.5 A g −1 , 218 F g −1 at a current density of 20 A g −1 , and high capacitance retention of 91.3% after charging/discharging 5,000 cycles.

  13. Performance assessment of simple and modified cycle turboshaft gas turbines

    Directory of Open Access Journals (Sweden)

    Barinyima Nkoi

    2013-06-01

    Full Text Available This paper focuses on investigations encompassing comparative assessment of gas turbine cycle options. More specifically, investigation was carried out of technical performance of turboshaft engine cycles based on existing simple cycle (SC and its projected modified cycles for civil helicopter application. Technically, thermal efficiency, specific fuel consumption, and power output are of paramount importance to the overall performance of gas turbine engines. In course of carrying out this research, turbomatch software established at Cranfield University based on gas turbine theory was applied to conduct simulation of a simple cycle (baseline two-spool helicopter turboshaft engine model with free power turbine. Similarly, some modified gas turbine cycle configurations incorporating unconventional components, such as engine cycle with low pressure compressor (LPC zero-staged, recuperated engine cycle, and intercooled/recuperated (ICR engine cycle, were also simulated. In doing so, design point (DP and off-design point (OD performances of the engine models were established. The percentage changes in performance parameters of the modified cycle engines over the simple cycle were evaluated and it was found that to a large extent, the modified engine cycles with unconventional components exhibit better performances in terms of thermal efficiency and specific fuel consumption than the traditional simple cycle engine. This research made use of public domain open source references.

  14. ZnO-nanorod-array/p-GaN high-performance ultra-violet light emitting devices prepared by simple solution synthesis

    Science.gov (United States)

    Jha, Shrawan Kumar; Luan, Chunyan; To, Chap Hang; Kutsay, Oleksandr; Kováč, Jaroslav; Zapien, Juan Antonio; Bello, Igor; Lee, Shuit-Tong

    2012-11-01

    Pure ultra-violet (UV) (378 nm) electroluminescence (EL) from zinc oxide (ZnO)-nanorod-array/p-gallium nitride (GaN) light emitting devices (LEDs) is demonstrated at low bias-voltages (˜4.3 V). Devices were prepared merely by solution-synthesis, without any involvement of sophisticated material growth techniques or preparation methods. Three different luminescence characterization techniques, i.e., photo-luminescence, cathodo-luminescence, and EL, provided insight into the nature of the UV emission mechanism in solution-synthesized LEDs. Bias dependent EL behaviour revealed blue-shift of EL peaks and increased peak sharpness, with increasing the operating voltage. Accelerated bias stress tests showed very stable and repeatable electrical and EL performance of the solution-synthesized nanorod LEDs.

  15. Improved in-tube electro-membrane extraction followed by high-performance liquid chromatography for simple and selective determination of ionic compounds: Optimization by central composite design.

    Science.gov (United States)

    Bazregar, Mohammad; Rajabi, Maryam; Yamini, Yadollah; Asghari, Alireza

    2017-07-01

    In this work, an efficient sample clean-up method, named in-tube electro-membrane extraction, is modified to resolve the formation of bubbles in the extraction process. This modified method is applied for the extraction of two model analytes including tartrazine and sunset yellow from food samples. The method is based on the electro-kinetic migration of ionized compounds by the application of an electrical potential difference, and on this basis the analytes under investigation, as anionic compounds, simply migrate from the donor phase and concentrate in the acceptor phase. A thin polypropylene sheet placed in the tube acts as a support for the membrane solvent, and it separates 30 μL of the aqueous acceptor from 1.2 mL of the aqueous donor. This setup can be used to solve the problem of extracting highly hydrophilic analytes. Response surface methodology is used for optimization of the experimental parameters so that under the optimized conditions, the method provides a good linearity in the range of 50-1000 ng/mL, low limits of detection (15-25 ng/mL), good extraction repeatabilities (relative standard deviations below 8.1%, n = 5), and high extraction recoveries (54-76%). © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. An evaporation-assisted dispersive liquid-liquid microextraction technique as a simple tool for high performance liquid chromatography tandem-mass spectrometry determination of insecticides in wine.

    Science.gov (United States)

    Timofeeva, Irina; Kanashina, Daria; Moskvin, Leonid; Bulatov, Andrey

    2017-08-25

    A sample pre-treatment technique based on evaporation-assisted dispersive liquid-liquid microextraction (EVA-DLLME), followed by HPLC-MS/MS has been developed for the determination of organophosphate insecticides (malathion, diazinon, phosalone) in wine samples. The procedure includes the addition of mixture of organic solvents (with density higher than water), consisting of the extraction (low density) and volatile (high density) solvents, to aqueous sample followed by heating of the mixture obtained, what promotes the volatile solvent evaporation and moving extraction solvent droplets from down to top of the aqueous sample and, as a consequence, microextraction of target analytes. To initiate the evaporation process an initiator is required. It was established that hexanol (extraction solvent) and dichloromethane (volatile solvent) mixture (1:1, v/v) provides effective microextraction of the insecticides from wine samples with recovery from 92 to 103%. The conditions of insecticides' microextraction such as selection of extraction solvent, ratio of hexanol/dichloromethane and hexanol/sample, type and concentration of initiator, and effect of ethanol as one of the main components of wine have been studied. Under optimal experimental conditions the linear detection ranges were found to be 10 -7 -10 -3 gL -1 for malathion, 10 -9 -10 -4 gL -1 for diazinon, and 10 -6 -10 -2 gL -1 for phosalone. The LODs, calculated from a blank test, based on 3σ, found to be 3×10 -8 gL -1 for malathion, 3×10 -10 gL -1 for diazinon and 3×10 -7 gL -1 for phosalone. The advantages of EVA-DLLME are the rapidity, simplicity, high sample throughput and low cost. As an outcome, the analytical results agreed fairly well with the results obtained by a reference GC-MS method. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Mesoporous anatase TiO2/reduced graphene oxide nanocomposites: A simple template-free synthesis and their high photocatalytic performance

    International Nuclear Information System (INIS)

    Zhou, Qi; Zhong, Yong-Hui; Chen, Xing; Huang, Xing-Jiu; Wu, Yu-Cheng

    2014-01-01

    Graphical abstract: - Highlights: • Mesoporous TiO 2 nanoparticles with anatase phase were assembled on reduced graphene oxide via a template-free one-step hydrothermal method. • The TiO 2 /rGO nanocomposites have better adsorption capacity and photocatalytic degradation efficiency for dyes removal. • Improved dye adsorption and photogenerated charge separation are responsible for enhanced activity. - Abstract: Mesoporous anatase phase TiO 2 was assembled on reduced graphene oxide (rGO) using a template-free one-step hydrothermal process. The nanocomposites were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, and Brunauer–Emmett–Teller (BET) surface area. Morphology of TiO 2 was related to the content of graphene oxide. TiO 2 /rGO nanocomposites exhibited excellent photocatalytic activity for the photo-degradation of methyl orange. The degradation rate was 4.5 times greater than that of pure TiO 2 nanoparticles. This difference was attributed to the thin two-dimensional graphene sheet. The graphene sheet had a large surface area, high adsorption capacity, and acted as a good electron acceptor for the transfer of photo-generated electrons from the conduction band of TiO 2 . The enhanced surface adsorption characteristics and excellent charge transport separation were independent properties of the photocatalytic degradation process

  18. Simple Motor Control Concept Results High Efficiency at High Velocities

    Science.gov (United States)

    Starin, Scott; Engel, Chris

    2013-09-01

    The need for high velocity motors in space applications for reaction wheels and detectors has stressed the limits of Brushless Permanent Magnet Motors (BPMM). Due to inherent hysteresis core losses, conventional BPMMs try to balance the need for torque verses hysteresis losses. Cong-less motors have significantly less hysteresis losses but suffer from lower efficiencies. Additionally, the inherent low inductance in cog-less motors result in high ripple currents or high switching frequencies, which lowers overall efficiency and increases performance demands on the control electronics.However, using a somewhat forgotten but fully qualified technology of Isotropic Magnet Motors (IMM), extremely high velocities may be achieved at low power input using conventional drive electronics. This paper will discuss the trade study efforts and empirical test data on a 34,000 RPM IMM.

  19. A simple, low-cost and eco-friendly approach to synthesize single-crystalline LiMn2O4 nanorods with high electrochemical performance for lithium-ion batteries

    International Nuclear Information System (INIS)

    Zhao, Hongyuan; Li, Fang; Liu, Xingquan; Xiong, Weiqiang; Chen, Bing; Shao, Huailing; Que, Dongyang; Zhang, Zheng; Wu, Yue

    2015-01-01

    The single-crystalline LiMn 2 O 4 nanorods were successfully synthesized by a simple, low-cost and eco-friendly approach in which the γ-MnOOH nanorods were prepared through a facile hydrothermal process, in which KMnO 4 was reduced by anhydrous alcohol (CH 3 CH 2 OH) without adding any template reagent or additional surfactant. The crystal structures and morphologies of synthesized materials were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM), respectively. The results showed that the γ-MnOOH nanorods had high crystallinity and well-shaped morphology with an average diameter of 200 nm and an average length of 12 μm. For the resulting LiMn 2 O 4 nanorods, the electrochemical properties were investigated by galvanostatic charge-discharge test, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). For the optimal LiMn 2 O 4 nanorods, the initial discharge capacity was 123.5 mAh g −1 and remained 110.2 mAh g −1 after 100 cycles at 1.0 C in the voltage range of 3.20∼4.35 V. Moreover, the optimal LiMn 2 O 4 nanorods can present superior rate performance, especially the capacity recovery performance as the charge-discharge rate restores to 0.1 C from 5.0 C. Such excellent electrochemical performance could make them to be the promising cathode material for high performance lithium-ion batteries

  20. Circadian Effects on Simple Components of Complex Task Performance

    Science.gov (United States)

    Clegg, Benjamin A.; Wickens, Christopher D.; Vieane, Alex Z.; Gutzwiller, Robert S.; Sebok, Angelia L.

    2015-01-01

    The goal of this study was to advance understanding and prediction of the impact of circadian rhythm on aspects of complex task performance during unexpected automation failures, and subsequent fault management. Participants trained on two tasks: a process control simulation, featuring automated support; and a multi-tasking platform. Participants then completed one task in a very early morning (circadian night) session, and the other during a late afternoon (circadian day) session. Small effects of time of day were seen on simple components of task performance, but impacts on more demanding components, such as those that occur following an automation failure, were muted relative to previous studies where circadian rhythm was compounded with sleep deprivation and fatigue. Circadian low participants engaged in compensatory strategies, rather than passively monitoring the automation. The findings and implications are discussed in the context of a model that includes the effects of sleep and fatigue factors.

  1. A simple multi-residue method for the determination of pesticides in fruits and vegetables using a methanolic extraction and ultra-high-performance liquid chromatography-tandem mass spectrometry: optimization and extension of scope.

    Science.gov (United States)

    Hanot, V; Goscinny, S; Deridder, M

    2015-03-06

    In 2004, a new multi-residue pesticides method had been published using methanol as extraction solvent. Our goal for this study was to optimize the analytical scheme while extending the compound scope from 19 to 200 pesticides. The main changes from the original method take place at the sample extraction and processing with a special attention to make the overall method fit for routine analysis with minimal cost. Hence, after a quick Ultra-Turrax homogenization with a methanolic solution, the sample is simply diluted before the separation and detection by ultra-high-performance liquid chromatography and MS/MS detection for quantitative and confirmatory purposes. The performance of the method including limits of quantification (LOQs), linearity, matrix effect, precision was evaluated during validation in accordance with the European Union SANCO/12571/2013 regulatory guidelines. Two representative matrices, lettuce and orange, were selected and fortified at two concentration levels for these experiments. At the LOQ and ten times the LOQ, recoveries of the analytes were mostly within 70-120%, with coefficients of variation lower than 25% in intra-day repeatability conditions. In addition to being simple and fast, these results demonstrate the suitability of the optimized method for the analysis of large scope pesticides in routine laboratories. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Development and validation of a simple high performance thin layer chromatography method combined with direct 1,1-diphenyl-2-picrylhydrazyl assay to quantify free radical scavenging activity in wine.

    Science.gov (United States)

    Agatonovic-Kustrin, Snezana; Morton, David W; Yusof, Ahmad P

    2016-04-15

    The aim of this study was to: (a) develop a simple, high performance thin layer chromatographic (HPTLC) method combined with direct 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay to rapidly assess and compare free radical scavenging activity or anti-oxidant activity for major classes of polyphenolics present in wines; and (b) to investigate relationship between free radical scavenging activity to the total polyphenolic content (TPC) and total antioxidant capacity (TAC) in the wine samples. The most potent free radical scavengers that we tested for in the wine samples were found to be resveratrol (polyphenolic non-flavonoid) and rutin (flavonoid), while polyphenolic acids (caffeic acid and gallic acid) although present in all wine samples were found to be less potent free radical scavengers. Therefore, the total antioxidant capacity was mostly affected by the presence of resveratrol and rutin, while total polyphenolic content was mostly influenced by the presence of the less potent free radical scavengers gallic and caffeic acids. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Comparison of Simple Versus Performance-Based Fall Prediction Models

    Directory of Open Access Journals (Sweden)

    Shekhar K. Gadkaree BS

    2015-05-01

    Full Text Available Objective: To compare the predictive ability of standard falls prediction models based on physical performance assessments with more parsimonious prediction models based on self-reported data. Design: We developed a series of fall prediction models progressing in complexity and compared area under the receiver operating characteristic curve (AUC across models. Setting: National Health and Aging Trends Study (NHATS, which surveyed a nationally representative sample of Medicare enrollees (age ≥65 at baseline (Round 1: 2011-2012 and 1-year follow-up (Round 2: 2012-2013. Participants: In all, 6,056 community-dwelling individuals participated in Rounds 1 and 2 of NHATS. Measurements: Primary outcomes were 1-year incidence of “ any fall ” and “ recurrent falls .” Prediction models were compared and validated in development and validation sets, respectively. Results: A prediction model that included demographic information, self-reported problems with balance and coordination, and previous fall history was the most parsimonious model that optimized AUC for both any fall (AUC = 0.69, 95% confidence interval [CI] = [0.67, 0.71] and recurrent falls (AUC = 0.77, 95% CI = [0.74, 0.79] in the development set. Physical performance testing provided a marginal additional predictive value. Conclusion: A simple clinical prediction model that does not include physical performance testing could facilitate routine, widespread falls risk screening in the ambulatory care setting.

  4. A Simple Method for High-Lift Propeller Conceptual Design

    Science.gov (United States)

    Patterson, Michael; Borer, Nick; German, Brian

    2016-01-01

    In this paper, we present a simple method for designing propellers that are placed upstream of the leading edge of a wing in order to augment lift. Because the primary purpose of these "high-lift propellers" is to increase lift rather than produce thrust, these props are best viewed as a form of high-lift device; consequently, they should be designed differently than traditional propellers. We present a theory that describes how these props can be designed to provide a relatively uniform axial velocity increase, which is hypothesized to be advantageous for lift augmentation based on a literature survey. Computational modeling indicates that such propellers can generate the same average induced axial velocity while consuming less power and producing less thrust than conventional propeller designs. For an example problem based on specifications for NASA's Scalable Convergent Electric Propulsion Technology and Operations Research (SCEPTOR) flight demonstrator, a propeller designed with the new method requires approximately 15% less power and produces approximately 11% less thrust than one designed for minimum induced loss. Higher-order modeling and/or wind tunnel testing are needed to verify the predicted performance.

  5. High performance homes

    DEFF Research Database (Denmark)

    Beim, Anne; Vibæk, Kasper Sánchez

    2014-01-01

    Can prefabrication contribute to the development of high performance homes? To answer this question, this chapter defines high performance in more broadly inclusive terms, acknowledging the technical, architectural, social and economic conditions under which energy consumption and production occur....... Consideration of all these factors is a precondition for a truly integrated practice and as this chapter demonstrates, innovative project delivery methods founded on the manufacturing of prefabricated buildings contribute to the production of high performance homes that are cost effective to construct, energy...

  6. A simple one-step ultrasonic-assisted extraction and derivatization method coupling to high-performance liquid chromatographyfor the determination of ε-aminocaproic acid and amino acids in cosmetics.

    Science.gov (United States)

    Du, Yuanqi; Xia, Ling; Xiao, Xiaohua; Li, Gongke; Chen, Xiaoguang

    2018-06-15

    Nowadays, the safety of cosmetics is a widespread concern. Amines are common cosmetic additives. Some of them such as amino acids are beneficial. Another kind of amines, however, ε-aminocaproic acid (EACA) is prohibited to add into cosmetics for its adverse reactions. In this study, a simple, rapid, sensitive and eco-friendly one-step ultrasonic-assisted extraction and derivatization (UAE-D) method was developed for determination of EACA and amino acids in cosmetics by coupling with high-performance liquid chromatography (HPLC). By using this sample preparation method, extraction and derivatization of EACA and amino acids were finished in one step in ultrasound field. During this procedure, 4-fluoro-7-nitrobenzofurazan (NBD-F)was applied as derivatization reagent. The extraction conditions including the amount of NBD-F, extraction and derivatization temperature, the ultrasonic vibration time and pH value of the aqueous phase were evaluated. Meanwhile, the extraction mechanism was investigated. Under optimized conditions, the method detection limits were 0.086-0.15 μg/L, and method quantitation limits were 0.29-0.47 μg/L with RSDs less than 3.7% (n = 3). The recoveries of EACA and amino acids obtained from cosmetic samples were in range from 76.9% to 122.3%. Amino acids were found in all selected samples and quantified in range from 1.9 ± 0.9 to 677.2 ± 17.9 μg/kg. And EACA was found and quantified with the contents of 1284.3 ± 22.1 μg/kg in a toner sample. This UAE-D-HPLC method shortened and simplified the sample pretreatment as well as enhanced the sensitivity of analytical method. In our record, only 10 min was needed for the total sample preparation process. And the method detection limits were two orders of magnitude less than literature reports. Furthermore, we reduced the consumption of solvent and minimized the usage of organic solvents, which made our method moving towards green analytical chemistry. In brief, our UAE

  7. High Performance Marine Vessels

    CERN Document Server

    Yun, Liang

    2012-01-01

    High Performance Marine Vessels (HPMVs) range from the Fast Ferries to the latest high speed Navy Craft, including competition power boats and hydroplanes, hydrofoils, hovercraft, catamarans and other multi-hull craft. High Performance Marine Vessels covers the main concepts of HPMVs and discusses historical background, design features, services that have been successful and not so successful, and some sample data of the range of HPMVs to date. Included is a comparison of all HPMVs craft and the differences between them and descriptions of performance (hydrodynamics and aerodynamics). Readers will find a comprehensive overview of the design, development and building of HPMVs. In summary, this book: Focuses on technology at the aero-marine interface Covers the full range of high performance marine vessel concepts Explains the historical development of various HPMVs Discusses ferries, racing and pleasure craft, as well as utility and military missions High Performance Marine Vessels is an ideal book for student...

  8. High performance systems

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, M.B. [comp.

    1995-03-01

    This document provides a written compilation of the presentations and viewgraphs from the 1994 Conference on High Speed Computing given at the High Speed Computing Conference, {open_quotes}High Performance Systems,{close_quotes} held at Gleneden Beach, Oregon, on April 18 through 21, 1994.

  9. Responsive design high performance

    CERN Document Server

    Els, Dewald

    2015-01-01

    This book is ideal for developers who have experience in developing websites or possess minor knowledge of how responsive websites work. No experience of high-level website development or performance tweaking is required.

  10. High Performance Macromolecular Material

    National Research Council Canada - National Science Library

    Forest, M

    2002-01-01

    .... In essence, most commercial high-performance polymers are processed through fiber spinning, following Nature and spider silk, which is still pound-for-pound the toughest liquid crystalline polymer...

  11. The Relation between Past Flows and Future Performance: Simple Investment Strategies in the Mutual Fund Sector

    Directory of Open Access Journals (Sweden)

    Martin Rohleder

    2015-02-01

    Full Text Available In the mutual fund literature, it is an established fact that investors “chase past performance”. However, the opposite impact of flows on performance is widely discussed. Mainly, liquidity costs are held responsible for short-term erosion of performance, while high inflows enhance performance over longer horizons. I investigate this relation for various groups of equity, bond, and money market funds and find significant outperformance in high inflow funds over several months, especially for specific bond fund groups. In addition, I test whether this information can be exploited using simple investment strategies but find that the abnormal returns are too low to offset associated costs.

  12. Clojure high performance programming

    CERN Document Server

    Kumar, Shantanu

    2013-01-01

    This is a short, practical guide that will teach you everything you need to know to start writing high performance Clojure code.This book is ideal for intermediate Clojure developers who are looking to get a good grip on how to achieve optimum performance. You should already have some experience with Clojure and it would help if you already know a little bit of Java. Knowledge of performance analysis and engineering is not required. For hands-on practice, you should have access to Clojure REPL with Leiningen.

  13. High Performance Concrete

    Directory of Open Access Journals (Sweden)

    Traian Oneţ

    2009-01-01

    Full Text Available The paper presents the last studies and researches accomplished in Cluj-Napoca related to high performance concrete, high strength concrete and self compacting concrete. The purpose of this paper is to raid upon the advantages and inconveniences when a particular concrete type is used. Two concrete recipes are presented, namely for the concrete used in rigid pavement for roads and another one for self-compacting concrete.

  14. High performance polymeric foams

    International Nuclear Information System (INIS)

    Gargiulo, M.; Sorrentino, L.; Iannace, S.

    2008-01-01

    The aim of this work was to investigate the foamability of high-performance polymers (polyethersulfone, polyphenylsulfone, polyetherimide and polyethylenenaphtalate). Two different methods have been used to prepare the foam samples: high temperature expansion and two-stage batch process. The effects of processing parameters (saturation time and pressure, foaming temperature) on the densities and microcellular structures of these foams were analyzed by using scanning electron microscopy

  15. High performance conductometry

    International Nuclear Information System (INIS)

    Saha, B.

    2000-01-01

    Inexpensive but high performance systems have emerged progressively for basic and applied measurements in physical and analytical chemistry on one hand, and for on-line monitoring and leak detection in plants and facilities on the other. Salient features of the developments will be presented with specific examples

  16. Danish High Performance Concretes

    DEFF Research Database (Denmark)

    Nielsen, M. P.; Christoffersen, J.; Frederiksen, J.

    1994-01-01

    In this paper the main results obtained in the research program High Performance Concretes in the 90's are presented. This program was financed by the Danish government and was carried out in cooperation between The Technical University of Denmark, several private companies, and Aalborg University...... concretes, workability, ductility, and confinement problems....

  17. High performance homes

    DEFF Research Database (Denmark)

    Beim, Anne; Vibæk, Kasper Sánchez

    2014-01-01

    . Consideration of all these factors is a precondition for a truly integrated practice and as this chapter demonstrates, innovative project delivery methods founded on the manufacturing of prefabricated buildings contribute to the production of high performance homes that are cost effective to construct, energy...

  18. High-Performance Networking

    CERN Multimedia

    CERN. Geneva

    2003-01-01

    The series will start with an historical introduction about what people saw as high performance message communication in their time and how that developed to the now to day known "standard computer network communication". It will be followed by a far more technical part that uses the High Performance Computer Network standards of the 90's, with 1 Gbit/sec systems as introduction for an in depth explanation of the three new 10 Gbit/s network and interconnect technology standards that exist already or emerge. If necessary for a good understanding some sidesteps will be included to explain important protocols as well as some necessary details of concerned Wide Area Network (WAN) standards details including some basics of wavelength multiplexing (DWDM). Some remarks will be made concerning the rapid expanding applications of networked storage.

  19. Development of the fast, simple and fully validated high performance liquid chromatographic method with diode array detector for quantification of testosterone esters in an oil-based injectable dosage form.

    Science.gov (United States)

    Kozlik, Petr; Tircova, Barbora

    2016-11-01

    Counterfeit steroids are available on the black market, ultimately to consumers who believe they are buying a legitimate pharmaceutical item from the labeled company. In many cases, counterfeit steroids can contain lower doses or some products can be overdosed. This can unwittingly expose users to a significant health risks. The mixture of testosterone propionate, phenylpropionate, isocaproate and decanoate in an oil-based injectable dosage form belongs to the one of the most misused illicit drugs by a variety of athletes. This study developed a new, fast, simple and reliable HPLC method combined with a simple sample preparation step to determine testosterone propionate, phenylpropionate, isocaproate and decanoate in an oil-based injectable dosage form without the use of sophisticated and expensive instrumentation. The developed analytical procedure provides high throughput of samples where LC analysis takes only 6min and sample preparation of oil matrix in one step takes approximately 10min with precision ranging from 1.03 to 3.38% (RSD), and accuracy (relative error %) within ±2.01%. This method was found to be precise, linear, accurate, sensitive, selective and robust for routine application in screening of commercial pharmaceutical products based on content of mentioned testosterone esters in their oil-based injectable dosage form for counterfeit drugs. This method was successfully applied to the analysis of nine samples of commercial testosterone mixtures purchased from various sources and will be further used as an effective screening method for determination of previously mentioned testosterone esters in samples confiscated by Institute of Forensic Science (Slovakia) during the illegal trade. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. High performance data transfer

    Science.gov (United States)

    Cottrell, R.; Fang, C.; Hanushevsky, A.; Kreuger, W.; Yang, W.

    2017-10-01

    The exponentially increasing need for high speed data transfer is driven by big data, and cloud computing together with the needs of data intensive science, High Performance Computing (HPC), defense, the oil and gas industry etc. We report on the Zettar ZX software. This has been developed since 2013 to meet these growing needs by providing high performance data transfer and encryption in a scalable, balanced, easy to deploy and use way while minimizing power and space utilization. In collaboration with several commercial vendors, Proofs of Concept (PoC) consisting of clusters have been put together using off-the- shelf components to test the ZX scalability and ability to balance services using multiple cores, and links. The PoCs are based on SSD flash storage that is managed by a parallel file system. Each cluster occupies 4 rack units. Using the PoCs, between clusters we have achieved almost 200Gbps memory to memory over two 100Gbps links, and 70Gbps parallel file to parallel file with encryption over a 5000 mile 100Gbps link.

  1. Raman spectroscopy on simple molecular systems at very high density

    International Nuclear Information System (INIS)

    Schiferl, D.; LeSar, R.S.; Moore, D.S.

    1988-01-01

    We present an overview of how Raman spectroscopy is done on simple molecular substances at high pressures. Raman spectroscopy is one of the most powerful tools for studying these substances. It is often the quickest means to explore changes in crystal and molecular structures, changes in bond strength, and the formation of new chemical species. Raman measurements have been made at pressures up to 200 GPa (2 Mbar). Even more astonishing is the range of temperatures (4-5200/degree/K) achieved in various static and dynamic (shock-wave) pressure experiments. One point we particularly wish to emphasize is the need for a good theoretical understanding to properly interpret and use experimental results. This is particularly true at ultra-high pressures, where strong crystal field effects can be misinterpreted as incipient insulator-metal transitions. We have tried to point out apparatus, techniques, and results that we feel are particularly noteworthy. We have also included some of the /open quotes/oral tradition/close quotes/ of high pressure Raman spectroscopy -- useful little things that rarely or never appear in print. Because this field is rapidly expanding, we discuss a number of exciting new techniques that have been informally communicated to us, especially those that seem to open new possibilities. 58 refs., 18 figs

  2. High performance sapphire windows

    Science.gov (United States)

    Bates, Stephen C.; Liou, Larry

    1993-02-01

    High-quality, wide-aperture optical access is usually required for the advanced laser diagnostics that can now make a wide variety of non-intrusive measurements of combustion processes. Specially processed and mounted sapphire windows are proposed to provide this optical access to extreme environment. Through surface treatments and proper thermal stress design, single crystal sapphire can be a mechanically equivalent replacement for high strength steel. A prototype sapphire window and mounting system have been developed in a successful NASA SBIR Phase 1 project. A large and reliable increase in sapphire design strength (as much as 10x) has been achieved, and the initial specifications necessary for these gains have been defined. Failure testing of small windows has conclusively demonstrated the increased sapphire strength, indicating that a nearly flawless surface polish is the primary cause of strengthening, while an unusual mounting arrangement also significantly contributes to a larger effective strength. Phase 2 work will complete specification and demonstration of these windows, and will fabricate a set for use at NASA. The enhanced capabilities of these high performance sapphire windows will lead to many diagnostic capabilities not previously possible, as well as new applications for sapphire.

  3. Simple patterned nanofiber scaffolds and its enhanced performance in immunoassay.

    Directory of Open Access Journals (Sweden)

    Jing Wang

    Full Text Available Cancer has become the leading cause of death worldwide; early diagnosis and treatment of cancers is critical for the survival of the patients. The concentration of cancer markers in easy-to-access biological fluids can provide great assistance in screening for occult primary cancers, distinguishing malignant from benign findings, determining prognosis and prediction for cancer patients. The multiplex detection technology of a panel of cancer markers can greatly increase the accuracy of disease diagnosis. Herein, we briefly fabricate a high-throughput micro-immunoassay based on the electrospun polystyrene (PS substrates to improve detection sensitivity. The immunoassay was evaluated by analyzing three different cancer biomarkers (AFP, CEA, VEGF. For AFP, CEA, VEGF immunofluorescence assay, the LOD of assay conducted on electrospun PS substrates before or after plasma and the conventional PS substrates were 0.42, 0.10, 1.12 ng/mL, 0.57, 0.09, 1.24 ng/mL, and 159.75, 26.19, 385.59 pg/mL, respectively (P < 0.05. Due to the high porosity and large surface area-to-volume ratio which is the foremost merit of nanostructures, and the plasma treatment which make the hydrophobic PS nanofibers hydropholic, the nanofibers substrates showed sufficient retention of immunoassay functionality and high potential for capture molecules immobilization. Consequently, the immunofluorescence assay conducted on electrospun PS substrates could significantly enhance the sensitivity and limits of detection.

  4. Simple determination of L-hydroxyproline in idiopathic pulmonary fibrosis lung tissues of rats using non-extractive high-performance liquid chromatography coupled with fluorescence detection after pre-column derivatization with novel synthetic 9-acetylimidazol-carbazole.

    Science.gov (United States)

    Ren, Yan; Zhao, Juanjuan; Shi, Yanan; Chen, Caiyun; Chen, Xiangming; Lv, Changjun

    2017-08-05

    L-Hydroxyproline (L-Hyp) is an important biomarker for idiopathic pulmonary fibrosis (IPF). The quantitative methods based on high-performance liquid chromatography coupled with fluorescence detection after pre-column derivatization typically requires complicated derivatization conditions and obtains unstable derivatives. Here, a novel derivatization reagent, 9-acetylimidazol-carbazole, was synthesized for the first time to efficiently and rapidly label the amino groups of L-Hyp. The high-performance liquid chromatography method with pre-column derivatization was performed on an Agilent ZORBAX SB-C 18 column (4.6×250mm, 5μm). The product was measured using fluorescence detection at excitation and emission wavelengths of 232 and 370nm, respectively. The method was validated in specificity, linearity, limit of detection (66.7 fmol), limit of quantification (333.3fmol), intra-day precision (0.75%), inter-day precision (3.82%), stability (3.15%), and recovery (90.7-109.4%). The validated method was successfully applied to the determination of L-Hyp in the lung tissues of healthy and IPF rats. The results showed that the concentration of L-Hyp (3.64mg/g) in the IPF model was significantly higher than the concentration (2.33mg/g) in the healthy control group with P<0.01. This is a new method for the determination of L-Hyp and can be used for other amino acid-related studies in the future. Copyright © 2017. Published by Elsevier B.V.

  5. R high performance programming

    CERN Document Server

    Lim, Aloysius

    2015-01-01

    This book is for programmers and developers who want to improve the performance of their R programs by making them run faster with large data sets or who are trying to solve a pesky performance problem.

  6. Validated High Performance Liquid Chromatography Method for ...

    African Journals Online (AJOL)

    Purpose: To develop a simple, rapid and sensitive high performance liquid chromatography (HPLC) method for the determination of cefadroxil monohydrate in human plasma. Methods: Schimadzu HPLC with LC solution software was used with Waters Spherisorb, C18 (5 μm, 150mm × 4.5mm) column. The mobile phase ...

  7. Validated High Performance Liquid Chromatography Method for ...

    African Journals Online (AJOL)

    Purpose: To develop a simple, rapid and sensitive high performance liquid ... response, tailing factor and resolution of six replicate injections was < 3 %. ... Cefadroxil monohydrate, Human plasma, Pharmacokinetics Bioequivalence ... Drug-free plasma was obtained from the local .... Influence of probenicid on the renal.

  8. High performance work practices, innovation and performance

    DEFF Research Database (Denmark)

    Jørgensen, Frances; Newton, Cameron; Johnston, Kim

    2013-01-01

    Research spanning nearly 20 years has provided considerable empirical evidence for relationships between High Performance Work Practices (HPWPs) and various measures of performance including increased productivity, improved customer service, and reduced turnover. What stands out from......, and Africa to examine these various questions relating to the HPWP-innovation-performance relationship. Each paper discusses a practice that has been identified in HPWP literature and potential variables that can facilitate or hinder the effects of these practices of innovation- and performance...

  9. A Simple Thermoplastic Substrate Containing Hierarchical Silica Lamellae for High-Molecular-Weight DNA Extraction.

    Science.gov (United States)

    Zhang, Ye; Zhang, Yi; Burke, Jeffrey M; Gleitsman, Kristin; Friedrich, Sarah M; Liu, Kelvin J; Wang, Tza-Huei

    2016-12-01

    An inexpensive, magnetic thermoplastic nanomaterial is developed utilizing a hierarchical layering of micro- and nanoscale silica lamellae to create a high-surface-area and low-shear substrate capable of capturing vast amounts of ultrahigh-molecular-weight DNA. Extraction is performed via a simple 45 min process and is capable of achieving binding capacities up to 1 000 000 times greater than silica microparticles. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. A Simple Approach for Enhancing the Output Performance of Solar-Pumped Solid-State Lasers

    Directory of Open Access Journals (Sweden)

    Dawei Liang

    2009-01-01

    Full Text Available A simple truncated fused silica elliptical cavity is proposed to enhance the output performance of solar-pumped solid-state lasers. The imaging property of the truncated elliptical cavity ensures an enhanced absorption distribution within an Nd:YAG rod. Optimum pumping parameters are found through ZEMAX nonsequential ray-tracing and LASCAD laser cavity analyses. Compared with the output laser performance of a 3D-compound parabolic concentrator-2D-compound parabolic concentrator (3D-CPC-2D-CPC cavity, the truncated cavity provides 11% more multimode and 72.7% more TEM00 laser powers. A laser beam of high beam quality can be produced efficiently. The standard tracking error for multimode laser power is also reduced to only 4.0% by the truncated cavity.

  11. Validated method for the determination of perfluorinated compounds in placental tissue samples based on a simple extraction procedure followed by ultra-high performance liquid chromatography-tandem mass spectrometry analysis.

    Science.gov (United States)

    Martín, J; Rodríguez-Gómez, R; Zafra-Gómez, A; Alonso, E; Vílchez, J L; Navalón, A

    2016-04-01

    Xenobiotic exposure during pregnancy is inevitable. Determination of perfluorinated compounds (PFCs), chemicals described as environmental contaminants by Public Health Authorities due to their persistence, bioaccumulation and toxicity, is a challenge. In the present work, a method based on a simplified sample treatment involving freeze-drying, solvent extraction and dispersive clean-up of the extracts using C18 sorbents followed by an ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) analysis was developed and validated for the determination of five perfluorinated carboxylic acids (C4-C8) and perfluorooctane sulfonate (PFOS) in placental tissue samples. The most influential parameters affecting the extraction method and clean-up were optimized using Design of Experiments (DOE). The method was validated using matrix-matched calibration. Found limits of detection (LODs) ranged from 0.03 to 2 ng g(-1) and limits of quantification (LOQs) from 0.08 to 6 ng g(-1), while inter- and intra-day variability was under 14% in all cases. Recovery rates for spiked samples ranged from 94% to 113%. The method was satisfactorily applied for the determination of compounds in human placental tissue samples collected at delivery from 25 randomly selected women. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Precise Quantitative Assessment of the Clinical Performances of Two High-Flux Polysulfone Hemodialyzers in Hemodialysis: Validation of a Blood-Based Simple Kinetic Model Versus Direct Dialysis Quantification.

    Science.gov (United States)

    Lim, Paik-Seong; Lin, Yuyu; Chen, Minfeng; Xu, Xiaoqi; Shi, Yun; Bowry, Sudhir; Canaud, Bernard

    2018-05-01

    Highly permeable dialysis membranes with better design filters have contributed to improved solute removal and dialysis efficacy. However, solute membrane permeability needs to be well controlled to avoid increased loss of albumin that is considered to be detrimental for dialysis patients. A novel high-flux dialyzer type (FX CorDiax; Fresenius Medical Care) incorporating an advanced polysulfone membrane modified with nano-controlled spinning technology to enhance the elimination of a broader spectrum of uremic toxins has been released. The aim of this study was to compare in the clinical setting two dialyzer types having the same surface area, the current (FX dialyzer) and the new dialyzer generation (FX CorDiax), with respect to solute removal capacity over a broad spectrum of markers, including assessment of albumin loss based on a direct dialysis quantification method. We performed a crossover study following an A1-B-A2 design involving 10 patients. Phase A1 was 1 week of thrice-weekly bicarbonate hemodialysis with the FX dialyzer, 4 h per treatment; phase B was performed with a similar treatment regimen but with a new FX CorDiax dialyzer and finally the phase A2 was repeated with FX dialyzer as the former phase. Solute removal markers of interest were assessed from blood samples taken before and after treatment and from total spent dialysate collection (direct dialysis quantification) permitting a mass transfer calculation (mg/session into total spent dialysate/ultrafiltrate). On the blood side, there were no significant differences in the solute percent reduction between FX CorDiax 80 and FX 80. On the dialysate side, no difference was observed regarding eliminated mass of different solutes including β 2 -microglobulin (143.1 ± 33.6 vs. 138.3 ± 41.9 mg, P = 0.8), while the solute mass removal of total protein (1.65 ± 0.51 vs. 2.14 ± 0.75 g, P = 0.04), and albumin (0.41 ± 0.21 vs. 1.22 ± 0.51 g, P < 0.001) were

  13. Python high performance programming

    CERN Document Server

    Lanaro, Gabriele

    2013-01-01

    An exciting, easy-to-follow guide illustrating the techniques to boost the performance of Python code, and their applications with plenty of hands-on examples.If you are a programmer who likes the power and simplicity of Python and would like to use this language for performance-critical applications, this book is ideal for you. All that is required is a basic knowledge of the Python programming language. The book will cover basic and advanced topics so will be great for you whether you are a new or a seasoned Python developer.

  14. High performance germanium MOSFETs

    Energy Technology Data Exchange (ETDEWEB)

    Saraswat, Krishna [Department of Electrical Engineering, Stanford University, Stanford, CA 94305 (United States)]. E-mail: saraswat@stanford.edu; Chui, Chi On [Department of Electrical Engineering, Stanford University, Stanford, CA 94305 (United States); Krishnamohan, Tejas [Department of Electrical Engineering, Stanford University, Stanford, CA 94305 (United States); Kim, Donghyun [Department of Electrical Engineering, Stanford University, Stanford, CA 94305 (United States); Nayfeh, Ammar [Department of Electrical Engineering, Stanford University, Stanford, CA 94305 (United States); Pethe, Abhijit [Department of Electrical Engineering, Stanford University, Stanford, CA 94305 (United States)

    2006-12-15

    Ge is a very promising material as future channel materials for nanoscale MOSFETs due to its high mobility and thus a higher source injection velocity, which translates into higher drive current and smaller gate delay. However, for Ge to become main-stream, surface passivation and heterogeneous integration of crystalline Ge layers on Si must be achieved. We have demonstrated growth of fully relaxed smooth single crystal Ge layers on Si using a novel multi-step growth and hydrogen anneal process without any graded buffer SiGe layer. Surface passivation of Ge has been achieved with its native oxynitride (GeO {sub x}N {sub y} ) and high-permittivity (high-k) metal oxides of Al, Zr and Hf. High mobility MOSFETs have been demonstrated in bulk Ge with high-k gate dielectrics and metal gates. However, due to their smaller bandgap and higher dielectric constant, most high mobility materials suffer from large band-to-band tunneling (BTBT) leakage currents and worse short channel effects. We present novel, Si and Ge based heterostructure MOSFETs, which can significantly reduce the BTBT leakage currents while retaining high channel mobility, making them suitable for scaling into the sub-15 nm regime. Through full band Monte-Carlo, Poisson-Schrodinger and detailed BTBT simulations we show a dramatic reduction in BTBT and excellent electrostatic control of the channel, while maintaining very high drive currents in these highly scaled heterostructure DGFETs. Heterostructure MOSFETs with varying strained-Ge or SiGe thickness, Si cap thickness and Ge percentage were fabricated on bulk Si and SOI substrates. The ultra-thin ({approx}2 nm) strained-Ge channel heterostructure MOSFETs exhibited >4x mobility enhancements over bulk Si devices and >10x BTBT reduction over surface channel strained SiGe devices.

  15. High performance germanium MOSFETs

    International Nuclear Information System (INIS)

    Saraswat, Krishna; Chui, Chi On; Krishnamohan, Tejas; Kim, Donghyun; Nayfeh, Ammar; Pethe, Abhijit

    2006-01-01

    Ge is a very promising material as future channel materials for nanoscale MOSFETs due to its high mobility and thus a higher source injection velocity, which translates into higher drive current and smaller gate delay. However, for Ge to become main-stream, surface passivation and heterogeneous integration of crystalline Ge layers on Si must be achieved. We have demonstrated growth of fully relaxed smooth single crystal Ge layers on Si using a novel multi-step growth and hydrogen anneal process without any graded buffer SiGe layer. Surface passivation of Ge has been achieved with its native oxynitride (GeO x N y ) and high-permittivity (high-k) metal oxides of Al, Zr and Hf. High mobility MOSFETs have been demonstrated in bulk Ge with high-k gate dielectrics and metal gates. However, due to their smaller bandgap and higher dielectric constant, most high mobility materials suffer from large band-to-band tunneling (BTBT) leakage currents and worse short channel effects. We present novel, Si and Ge based heterostructure MOSFETs, which can significantly reduce the BTBT leakage currents while retaining high channel mobility, making them suitable for scaling into the sub-15 nm regime. Through full band Monte-Carlo, Poisson-Schrodinger and detailed BTBT simulations we show a dramatic reduction in BTBT and excellent electrostatic control of the channel, while maintaining very high drive currents in these highly scaled heterostructure DGFETs. Heterostructure MOSFETs with varying strained-Ge or SiGe thickness, Si cap thickness and Ge percentage were fabricated on bulk Si and SOI substrates. The ultra-thin (∼2 nm) strained-Ge channel heterostructure MOSFETs exhibited >4x mobility enhancements over bulk Si devices and >10x BTBT reduction over surface channel strained SiGe devices

  16. Fast and Simple Forensic Red Pen Ink Analysis Using Ultra-Performance Liquid Chromatography (UPLC)

    International Nuclear Information System (INIS)

    Lee, L.C.; Ying, S.L.; Wan Nur Syazwani Wan Mohamad Fuad; Ab Aziz Ishak; Khairul Osman

    2016-01-01

    Ultra-performance liquid chromatography (UPLC) is more effective than high performance liquid chromatography in terms of analysis speed and sensitivity. This paper presents a feasibility study on forensic red pen inks analysis using UPLC. A total of 12 varieties of red ball point pen inks were purchased from selected stationary shop. For each variety, four different individual pens were sampled to provide intra-variability within a particular variety of pen. The proposed approach is very simple that it only involved limited analysis step and chemicals. A total of 144 chromatograms were obtained from red ink entries extracted with 1.5 mL 80 % (v/v) acetonitrile. Peaks originated from pen inks were determined by comparing the chromatograms of both blank paper and blank solvent against that of ink samples. Subsequently, one-way ANOVA was conducted to discriminate all 66 possible pairs for red pen inks. Results showed that the proposed approach giving discriminating power of 95.45 %. The outcome of the study indicates that UPLC could be a fast and simple approach to red ball point pen inks analysis. (author)

  17. High Performance Computing Multicast

    Science.gov (United States)

    2012-02-01

    A History of the Virtual Synchrony Replication Model,” in Replication: Theory and Practice, Charron-Bost, B., Pedone, F., and Schiper, A. (Eds...Performance Computing IP / IPv4 Internet Protocol (version 4.0) IPMC Internet Protocol MultiCast LAN Local Area Network MCMD Dr. Multicast MPI

  18. NGINX high performance

    CERN Document Server

    Sharma, Rahul

    2015-01-01

    System administrators, developers, and engineers looking for ways to achieve maximum performance from NGINX will find this book beneficial. If you are looking for solutions such as how to handle more users from the same system or load your website pages faster, then this is the book for you.

  19. A simple assay for the simultaneous determination of human plasma albendazole and albendazole sulfoxide levels by high performance liquid chromatography in tandem mass spectrometry with solid-phase extraction.

    Science.gov (United States)

    Wojnicz, Aneta; Cabaleiro-Ocampo, Teresa; Román-Martínez, Manuel; Ochoa-Mazarro, Dolores; Abad-Santos, Francisco; Ruiz-Nuño, Ana

    2013-11-15

    A simple, reproducible and fast (4 min chromatogram) method of liquid chromatography in tandem with mass spectrometry (LC/MS-MS) was developed to determine simultaneously the plasma levels of albendazole (ABZ) and its metabolite albendazole sulfoxide (ABZOX) for pharmacokinetic and clinical analysis. Each plasma sample was extracted by solid phase extraction (SPE) using phenacetin as internal standard (IS). The extracted sample was eluted with a Zorbax XDB-CN column using an isocratic method. The mobile phase consisting of water with 1% acetic acid (40%, A) and MeOH (60%, B), was used at a flow rate of 1 mL/min. ABZ and ABZOX were detected and identified by mass spectrometry with electrospray ionization (ESI) in the positive ion and multiple-reaction monitoring (MRM) mode. The method was linear in the range of 5-1000 ng/mL for ABZ and 10-1500 ng/mL (full validation) or 10-5000 ng/mL (partial validation) for ABZOX, with 5 and 10 ng/mL lower limit of quantification (LLOQ) for ABZ and ABZOX, respectively. The tests of accuracy and precision, matrix effect, extraction recovery and stability of the samples for both ABZ and ABZOX did not deviate more than 20% for the LLOQ and no more than 15% for other quality controls (QCs), according to regulatory agencies. © 2013.

  20. High performance proton accelerators

    International Nuclear Information System (INIS)

    Favale, A.J.

    1989-01-01

    In concert with this theme this paper briefly outlines how Grumman, over the past 4 years, has evolved from a company that designed and fabricated a Radio Frequency Quadrupole (RFQ) accelerator from the Los Alamos National Laboratory (LANL) physics and specifications to a company who, as prime contractor, is designing, fabricating, assembling and commissioning the US Army Strategic Defense Commands (USA SDC) Continuous Wave Deuterium Demonstrator (CWDD) accelerator as a turn-key operation. In the case of the RFQ, LANL scientists performed the physics analysis, established the specifications supported Grumman on the mechanical design, conducted the RFQ tuning and tested the RFQ at their laboratory. For the CWDD Program Grumman has the responsibility for the physics and engineering designs, assembly, testing and commissioning albeit with the support of consultants from LANL, Lawrence Berkeley Laboratory (LBL) and Brookhaven National laboratory. In addition, Culham Laboratory and LANL are team members on CWDD. LANL scientists have reviewed the physics design as well as a USA SDC review board. 9 figs

  1. Validation of a simple method for predicting the disinfection performance in a flow-through contactor.

    Science.gov (United States)

    Pfeiffer, Valentin; Barbeau, Benoit

    2014-02-01

    Despite its shortcomings, the T10 method introduced by the United States Environmental Protection Agency (USEPA) in 1989 is currently the method most frequently used in North America to calculate disinfection performance. Other methods (e.g., the Integrated Disinfection Design Framework, IDDF) have been advanced as replacements, and more recently, the USEPA suggested the Extended T10 and Extended CSTR (Continuous Stirred-Tank Reactor) methods to improve the inactivation calculations within ozone contactors. To develop a method that fully considers the hydraulic behavior of the contactor, two models (Plug Flow with Dispersion and N-CSTR) were successfully fitted with five tracer tests results derived from four Water Treatment Plants and a pilot-scale contactor. A new method based on the N-CSTR model was defined as the Partially Segregated (Pseg) method. The predictions from all the methods mentioned were compared under conditions of poor and good hydraulic performance, low and high disinfectant decay, and different levels of inactivation. These methods were also compared with experimental results from a chlorine pilot-scale contactor used for Escherichia coli inactivation. The T10 and Extended T10 methods led to large over- and under-estimations. The Segregated Flow Analysis (used in the IDDF) also considerably overestimated the inactivation under high disinfectant decay. Only the Extended CSTR and Pseg methods produced realistic and conservative predictions in all cases. Finally, a simple implementation procedure of the Pseg method was suggested for calculation of disinfection performance. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. A simple diethylene glycol-assisted synthesis and high rate performance of Li3V2(PO4)3/C composites as cathode material for Li-ion batteries

    International Nuclear Information System (INIS)

    Liu, Qianjin; Yang, Fei; Wang, Shuping; Feng, Lijun; Zhang, Wenjing; Wei, Huiying

    2013-01-01

    Spherical Li 3 V 2 (PO 4 ) 3 /C(LVP/C) composites were synthesized by sol–gel method using diethylene glycol as the spheroidizing medium and glucose as the carbon source. The crystal structure, morphology, the lithium diffusion behavior and high rates capacities were investigated using X-ray diffraction (XRD), scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS) and electrochemical methods. Results indicated that the sphere-like LVP/C sample prepared with 10 wt% glucose has a uniform carbon layer about 10 nm on the surfaces, and presented a high discharge capacity of 131.8, 126.5, 102.4, 82.8 mAh g −1 at 0.1, 2, 10, 20 C between 3.0 and 4.3 V with no obvious capacity fading during 200 cycles at the rate of 2 C. While in the voltage region of 3.0–4.8 V, it owned the largest reversible capacity of 169.4, 139.8, 121.7 mAh g −1 at 0.5, 1, 5 C, respectively. Its capacity retained 79.9% after 200 cycles at 2 C, and the apparent Li-ion diffusion coefficient was calculated to be 3.37 × 10 −9 cm 2 s −1

  3. Simple Retrofit High-Efficiency Natural Gas Water Heater Field Test

    Energy Technology Data Exchange (ETDEWEB)

    Schoenbauer, Ben [NorthernSTAR, St. Paul, MN (United States)

    2017-03-01

    High-performance water heaters are typically more time consuming and costly to install in retrofit applications, making high performance water heaters difficult to justify economically. However, recent advancements in high performance water heaters have targeted the retrofit market, simplifying installations and reducing costs. Four high efficiency natural gas water heaters designed specifically for retrofit applications were installed in single-family homes along with detailed monitoring systems to characterize their savings potential, their installed efficiencies, and their ability to meet household demands. The water heaters tested for this project were designed to improve the cost-effectiveness and increase market penetration of high efficiency water heaters in the residential retrofit market. The retrofit high efficiency water heaters achieved their goal of reducing costs, maintaining savings potential and installed efficiency of other high efficiency water heaters, and meeting the necessary capacity in order to improve cost-effectiveness. However, the improvements were not sufficient to achieve simple paybacks of less than ten years for the incremental cost compared to a minimum efficiency heater. Significant changes would be necessary to reduce the simple payback to six years or less. Annual energy savings in the range of $200 would also reduce paybacks to less than six years. These energy savings would require either significantly higher fuel costs (greater than $1.50 per therm) or very high usage (around 120 gallons per day). For current incremental costs, the water heater efficiency would need to be similar to that of a heat pump water heater to deliver a six year payback.

  4. Simple Retrofit High-Efficiency Natural Gas Water Heater Field Test

    Energy Technology Data Exchange (ETDEWEB)

    Schoenbauer, Ben [NorthernSTAR, St. Paul, MN (United States)

    2017-03-28

    High performance water heaters are typically more time consuming and costly to install in retrofit applications, making high performance water heaters difficult to justify economically. However, recent advancements in high performance water heaters have targeted the retrofit market, simplifying installations and reducing costs. Four high efficiency natural gas water heaters designed specifically for retrofit applications were installed in single-family homes along with detailed monitoring systems to characterize their savings potential, their installed efficiencies, and their ability to meet household demands. The water heaters tested for this project were designed to improve the cost-effectiveness and increase market penetration of high efficiency water heaters in the residential retrofit market. The retrofit high efficiency water heaters achieved their goal of reducing costs, maintaining savings potential and installed efficiency of other high efficiency water heaters, and meeting the necessary capacity in order to improve cost-effectiveness. However, the improvements were not sufficient to achieve simple paybacks of less than ten years for the incremental cost compared to a minimum efficiency heater. Significant changes would be necessary to reduce the simple payback to six years or less. Annual energy savings in the range of $200 would also reduce paybacks to less than six years. These energy savings would require either significantly higher fuel costs (greater than $1.50 per therm) or very high usage (around 120 gallons per day). For current incremental costs, the water heater efficiency would need to be similar to that of a heat pump water heater to deliver a six year payback.

  5. Exploring performance and power properties of modern multicore chips via simple machine models

    OpenAIRE

    Hager, Georg; Treibig, Jan; Habich, Johannes; Wellein, Gerhard

    2012-01-01

    Modern multicore chips show complex behavior with respect to performance and power. Starting with the Intel Sandy Bridge processor, it has become possible to directly measure the power dissipation of a CPU chip and correlate this data with the performance properties of the running code. Going beyond a simple bottleneck analysis, we employ the recently published Execution-Cache-Memory (ECM) model to describe the single- and multi-core performance of streaming kernels. The model refines the wel...

  6. Rating of Dynamic Coefficient for Simple Beam Bridge Design on High-Speed Railways

    Science.gov (United States)

    Diachenko, Leonid; Benin, Andrey; Smirnov, Vladimir; Diachenko, Anastasia

    2018-06-01

    The aim of the work is to improve the methodology for the dynamic computation of simple beam spans during the impact of high-speed trains. Mathematical simulation utilizing numerical and analytical methods of structural mechanics is used in the research. The article analyses parameters of the effect of high-speed trains on simple beam spanning bridge structures and suggests a technique of determining of the dynamic index to the live load. Reliability of the proposed methodology is confirmed by results of numerical simulation of high-speed train passage over spans with different speeds. The proposed algorithm of dynamic computation is based on a connection between maximum acceleration of the span in the resonance mode of vibrations and the main factors of stress-strain state. The methodology allows determining maximum and also minimum values of the main efforts in the construction that makes possible to perform endurance tests. It is noted that dynamic additions for the components of the stress-strain state (bending moments, transverse force and vertical deflections) are different. This condition determines the necessity for differentiated approach to evaluation of dynamic coefficients performing design verification of I and II groups of limiting state. The practical importance: the methodology of determining the dynamic coefficients allows making dynamic calculation and determining the main efforts in split beam spans without numerical simulation and direct dynamic analysis that significantly reduces the labour costs for design.

  7. Analysis of Simvastatin using a Simple and Fast High Performance ...

    African Journals Online (AJOL)

    simvastatin, and to apply the developed method to study the solubility of the ... samples. Results: The developed HPLC method showed good linearity (R2 = 0.9958 ± 0.0040. ... EXPERIMENTAL ... from the true value served as the measure of.

  8. A simple, tunable, and highly sensitive radio-frequency sensor.

    Science.gov (United States)

    Cui, Yan; Sun, Jiwei; He, Yuxi; Wang, Zheng; Wang, Pingshan

    2013-08-05

    We report a radio frequency (RF) sensor that exploits tunable attenuators and phase shifters to achieve high-sensitivity and broad band frequency tunability. Three frequency bands are combined to enable sensor operations from ∼20 MHz to ∼38 GHz. The effective quality factor ( Q eff ) of the sensor is as high as ∼3.8 × 10 6 with 200  μ l of water samples. We also demonstrate the measurement of 2-proponal-water-solution permittivity at 0.01 mole concentration level from ∼1 GHz to ∼10 GHz. Methanol-water solution and de-ionized water are used to calibrate the RF sensor for the quantitative measurements.

  9. Evaluating the performance of simple estimators for probit models with two dummy endogenous regressors

    DEFF Research Database (Denmark)

    Holm, Anders; Nielsen, Jacob Arendt

    2013-01-01

    This study considers the small sample performance of approximate but simple two-stage estimators for probit models with two endogenous binary covariates. Monte Carlo simulations showthat all the considered estimators, including the simulated maximum-likelihood (SML) estimation, of the trivariate ...

  10. High Performance Networks for High Impact Science

    Energy Technology Data Exchange (ETDEWEB)

    Scott, Mary A.; Bair, Raymond A.

    2003-02-13

    This workshop was the first major activity in developing a strategic plan for high-performance networking in the Office of Science. Held August 13 through 15, 2002, it brought together a selection of end users, especially representing the emerging, high-visibility initiatives, and network visionaries to identify opportunities and begin defining the path forward.

  11. Sensitive high performance liquid chromatographic method for the ...

    African Journals Online (AJOL)

    A new simple, sensitive, cost-effective and reproducible high performance liquid chromatographic (HPLC) method for the determination of proguanil (PG) and its metabolites, cycloguanil (CG) and 4-chlorophenylbiguanide (4-CPB) in urine and plasma is described. The extraction procedure is a simple three-step process ...

  12. Rapid and simple preparation of rhodamine 6G loaded HY zeolite for highly selective nitrite detection

    Science.gov (United States)

    Viboonratanasri, Duangkamon; Pabchanda, Suwat; Prompinit, Panida

    2018-05-01

    In this study, a simple, rapid and relatively less toxic method for rhodamine 6G dye adsorption on hydrogen-form Y-type zeolite for highly selective nitrite detection was demonstrated. The adsorption behavior was described by Langmuir isotherm and the adsorption process reached the equilibrium promptly within a minute. The developed test papers characterized by fluorescence technique display high sensing performance with wide working range (0.04-20.0 mg L-1) and high selectivity. The test papers show good reproducibility with relative standard deviation (RSD) of 7% for five replicated determinations of 3 mg L-1 of nitrite. The nitrite concentration determined by using the test paper was in the same range as using ion chromatography within a 95% confidence level. The test papers offer advantages in terms of low cost and practical usage enabling them to be a promising candidate for nitrite sensor in environmental samples, food, and fertilizers.

  13. Simple processing of high efficiency silicon solar cells

    International Nuclear Information System (INIS)

    Hamammu, I.M.; Ibrahim, K.

    2006-01-01

    Cost effective photovoltaic devices have been an area research since the development of the first solar cells, as cost is the major factor in their usage. Silicon solar cells have the biggest share in the photovoltaic market, though silicon os not the optimal material for solar cells. This work introduces a simplified approach for high efficiency silicon solar cell processing, by minimizing the processing steps and thereby reducing cost. The suggested procedure might also allow for the usage of lower quality materials compared to the one used today. The main features of the present work fall into: simplifying the diffusion process, edge shunt isolation and using acidic texturing instead of the standard alkaline processing. Solar cells of 17% efficiency have been produced using this procedure. Investigations on the possibility of improving the efficiency and using less quality material are still underway

  14. Numerical and Experimental Study on Mixing Performances of Simple and Vortex Micro T-Mixers

    Directory of Open Access Journals (Sweden)

    Mubashshir Ahmad Ansari

    2018-04-01

    Full Text Available Vortex flow increases the interface area of fluid streams by stretching along with providing continuous stirring action to the fluids in micromixers. In this study, experimental and numerical analyses on a design of micromixer that creates vortex flow were carried out, and the mixing performance was compared with a simple micro T-mixer. In the vortex micro T-mixer, the height of the inlet channels is half of the height of the main mixing channel. The inlet channel connects to the main mixing channel (micromixer at the one end at an offset position in a fashion that creates vortex flow. In the simple micro T-mixer, the height of the inlet channels is equal to the height of the channel after connection (main mixing channel. Mixing of fluids and flow field have been analyzed for Reynolds numbers in a range from 1–80. The study has been further extended to planar serpentine microchannels, which were combined with a simple and a vortex T-junction, to evaluate and verify their mixing performances. The mixing performance of the vortex T-mixer is higher than the simple T-mixer and significantly increases with the Reynolds number. The design is promising for efficiently increasing mixing simply at the T-junction and can be applied to all micromixers.

  15. High pressure chemistry of red phosphorus by photoactivated simple molecules

    Science.gov (United States)

    Ceppatelli, Matteo; Bini, Roberto; Fanetti, Samuele; Caporali, Maria; Peruzzini, Maurizio

    2013-06-01

    High pressure (HP) is very effective in reducing intermolecular distances and inducing unexpected chemical reactions. In particular the photoactivation of the reactants in HP conditions can lead to very efficient and selective processes. The chemistry of phosphorus is currently based on the white molecular form. The red polymeric allotrope, despite more stable and much less toxic, has not attracted much attention so far. However, switching from the white to the red form would benefit any industrial procedure, especially from an environmental point of view. On the other side, water and ethanol are renewable, environmental friendly and largely available molecules, usable as reactants and photoactivators in HP conditions. Here we report a study on the HP photoinduced reactivity of red phosphorus with water and ethanol, showing the possibility of very efficient and selective processes, leading to molecular hydrogen and valuable phosphorus compounds. The reactions have been studied by means of FTIR and Raman spectroscopy and pressure has been generated using DAC and SAC. HP reactivity has been activated by the two-photon absorption of near-UV wavelengths and occured in total absence of solvents, catalysts and radical initiators, at room T and mild pressure conditions (0.2-1.5 GPa).

  16. RavenDB high performance

    CERN Document Server

    Ritchie, Brian

    2013-01-01

    RavenDB High Performance is comprehensive yet concise tutorial that developers can use to.This book is for developers & software architects who are designing systems in order to achieve high performance right from the start. A basic understanding of RavenDB is recommended, but not required. While the book focuses on advanced topics, it does not assume that the reader has a great deal of prior knowledge of working with RavenDB.

  17. Simple and Reproducible Sample Preparation for Single-Shot Phosphoproteomics with High Sensitivity

    DEFF Research Database (Denmark)

    Jersie-Christensen, Rosa R.; Sultan, Abida; Olsen, Jesper V

    2016-01-01

    The traditional sample preparation workflow for mass spectrometry (MS)-based phosphoproteomics is time consuming and usually requires multiple steps, e.g., lysis, protein precipitation, reduction, alkylation, digestion, fractionation, and phosphopeptide enrichment. Each step can introduce chemical...... artifacts, in vitro protein and peptide modifications, and contaminations. Those often result in sample loss and affect the sensitivity, dynamic range and accuracy of the mass spectrometric analysis. Here we describe a simple and reproducible phosphoproteomics protocol, where lysis, denaturation, reduction......, and alkylation are performed in a single step, thus reducing sample loss and increasing reproducibility. Moreover, unlike standard cell lysis procedures the cell harvesting is performed at high temperatures (99 °C) and without detergents and subsequent need for protein precipitation. Phosphopeptides are enriched...

  18. A simple-architecture fibered transmission system for dissemination of high stability 100 MHz signals

    Science.gov (United States)

    Bakir, A.; Rocher, C.; Maréchal, B.; Bigler, E.; Boudot, R.; Kersalé, Y.; Millo, J.

    2018-05-01

    We report on the development of a simple-architecture fiber-based frequency distribution system used to transfer high frequency stability 100 MHz signals. This work is focused on the emitter and the receiver performances that allow the transmission of the radio-frequency signal over an optical fiber. The system exhibits a residual fractional frequency stability of 1 × 10-14 at 1 s integration time and in the low 10-16 range after 100 s. These performances are suitable to transfer the signal of frequency references such as those of a state-of-the-art hydrogen maser without any phase noise compensation scheme. As an application, we demonstrate the dissemination of such a signal through a 100 m long optical fiber without any degradation. The proposed setup could be easily extended for operating frequencies in the 10 MHz-1 GHz range.

  19. High-Performance Operating Systems

    DEFF Research Database (Denmark)

    Sharp, Robin

    1999-01-01

    Notes prepared for the DTU course 49421 "High Performance Operating Systems". The notes deal with quantitative and qualitative techniques for use in the design and evaluation of operating systems in computer systems for which performance is an important parameter, such as real-time applications......, communication systems and multimedia systems....

  20. Identifying High Performance ERP Projects

    OpenAIRE

    Stensrud, Erik; Myrtveit, Ingunn

    2002-01-01

    Learning from high performance projects is crucial for software process improvement. Therefore, we need to identify outstanding projects that may serve as role models. It is common to measure productivity as an indicator of performance. It is vital that productivity measurements deal correctly with variable returns to scale and multivariate data. Software projects generally exhibit variable returns to scale, and the output from ERP projects is multivariate. We propose to use Data Envelopment ...

  1. INL High Performance Building Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Jennifer D. Morton

    2010-02-01

    High performance buildings, also known as sustainable buildings and green buildings, are resource efficient structures that minimize the impact on the environment by using less energy and water, reduce solid waste and pollutants, and limit the depletion of natural resources while also providing a thermally and visually comfortable working environment that increases productivity for building occupants. As Idaho National Laboratory (INL) becomes the nation’s premier nuclear energy research laboratory, the physical infrastructure will be established to help accomplish this mission. This infrastructure, particularly the buildings, should incorporate high performance sustainable design features in order to be environmentally responsible and reflect an image of progressiveness and innovation to the public and prospective employees. Additionally, INL is a large consumer of energy that contributes to both carbon emissions and resource inefficiency. In the current climate of rising energy prices and political pressure for carbon reduction, this guide will help new construction project teams to design facilities that are sustainable and reduce energy costs, thereby reducing carbon emissions. With these concerns in mind, the recommendations described in the INL High Performance Building Strategy (previously called the INL Green Building Strategy) are intended to form the INL foundation for high performance building standards. This revised strategy incorporates the latest federal and DOE orders (Executive Order [EO] 13514, “Federal Leadership in Environmental, Energy, and Economic Performance” [2009], EO 13423, “Strengthening Federal Environmental, Energy, and Transportation Management” [2007], and DOE Order 430.2B, “Departmental Energy, Renewable Energy, and Transportation Management” [2008]), the latest guidelines, trends, and observations in high performance building construction, and the latest changes to the Leadership in Energy and Environmental Design

  2. Simple, cost effective & result oriented framework for supplier performance measurement in sports goods manufacturing industry

    Directory of Open Access Journals (Sweden)

    2011-09-01

    Full Text Available The emergences of global markets have increased competition worldwide. For the Sports Goods Manufacturing Industry which is considered to be an intensive supplier base industry with limited resources to sustain in what is already a very competitive market there is a need for the entire supply chain viz. raw material and machinery suppliers and manufacturers to measure their supplier's performance to reduce business risks and revenue losses. How to design & execute a simple, cost effective & result oriented Framework for Supplier Performance Measurement for sports goods manufacturing small - medium enterprises is the main aim of this research paper.

  3. Combining high productivity with high performance on commodity hardware

    DEFF Research Database (Denmark)

    Skovhede, Kenneth

    -like compiler for translating CIL bytecode on the CELL-BE. I then introduce a bytecode converter that transforms simple loops in Java bytecode to GPGPU capable code. I then introduce the numeric library for the Common Intermediate Language, NumCIL. I can then utilizing the vector programming model from Num......CIL and map this to the Bohrium framework. The result is a complete system that gives the user a choice of high-level languages with no explicit parallelism, yet seamlessly performs efficient execution on a number of hardware setups....

  4. High performance fuel technology development

    Energy Technology Data Exchange (ETDEWEB)

    Koon, Yang Hyun; Kim, Keon Sik; Park, Jeong Yong; Yang, Yong Sik; In, Wang Kee; Kim, Hyung Kyu [KAERI, Daejeon (Korea, Republic of)

    2012-01-15

    {omicron} Development of High Plasticity and Annular Pellet - Development of strong candidates of ultra high burn-up fuel pellets for a PCI remedy - Development of fabrication technology of annular fuel pellet {omicron} Development of High Performance Cladding Materials - Irradiation test of HANA claddings in Halden research reactor and the evaluation of the in-pile performance - Development of the final candidates for the next generation cladding materials. - Development of the manufacturing technology for the dual-cooled fuel cladding tubes. {omicron} Irradiated Fuel Performance Evaluation Technology Development - Development of performance analysis code system for the dual-cooled fuel - Development of fuel performance-proving technology {omicron} Feasibility Studies on Dual-Cooled Annular Fuel Core - Analysis on the property of a reactor core with dual-cooled fuel - Feasibility evaluation on the dual-cooled fuel core {omicron} Development of Design Technology for Dual-Cooled Fuel Structure - Definition of technical issues and invention of concept for dual-cooled fuel structure - Basic design and development of main structure components for dual- cooled fuel - Basic design of a dual-cooled fuel rod.

  5. High Performance Bulk Thermoelectric Materials

    Energy Technology Data Exchange (ETDEWEB)

    Ren, Zhifeng [Boston College, Chestnut Hill, MA (United States)

    2013-03-31

    Over 13 plus years, we have carried out research on electron pairing symmetry of superconductors, growth and their field emission property studies on carbon nanotubes and semiconducting nanowires, high performance thermoelectric materials and other interesting materials. As a result of the research, we have published 104 papers, have educated six undergraduate students, twenty graduate students, nine postdocs, nine visitors, and one technician.

  6. Simple and cost-effective fabrication of highly flexible, transparent superhydrophobic films with hierarchical surface design.

    Science.gov (United States)

    Kim, Tae-Hyun; Ha, Sung-Hun; Jang, Nam-Su; Kim, Jeonghyo; Kim, Ji Hoon; Park, Jong-Kweon; Lee, Deug-Woo; Lee, Jaebeom; Kim, Soo-Hyung; Kim, Jong-Man

    2015-03-11

    Optical transparency and mechanical flexibility are both of great importance for significantly expanding the applicability of superhydrophobic surfaces. Such features make it possible for functional surfaces to be applied to various glass-based products with different curvatures. In this work, we report on the simple and potentially cost-effective fabrication of highly flexible and transparent superhydrophobic films based on hierarchical surface design. The hierarchical surface morphology was easily fabricated by the simple transfer of a porous alumina membrane to the top surface of UV-imprinted polymeric micropillar arrays and subsequent chemical treatments. Through optimization of the hierarchical surface design, the resultant superhydrophobic films showed superior surface wetting properties (with a static contact angle of >170° and contact angle hysteresis of 82% at 550 nm wavelength). The superhydrophobic films were also experimentally found to be robust without significant degradation in the superhydrophobicity, even under repetitive bending and pressing for up to 2000 cycles. Finally, the practical usability of the proposed superhydorphobic films was clearly demonstrated by examining the antiwetting performance in real time while pouring water on the film and submerging the film in water.

  7. High performance in software development

    CERN Multimedia

    CERN. Geneva; Haapio, Petri; Liukkonen, Juha-Matti

    2015-01-01

    What are the ingredients of high-performing software? Software development, especially for large high-performance systems, is one the most complex tasks mankind has ever tried. Technological change leads to huge opportunities but challenges our old ways of working. Processing large data sets, possibly in real time or with other tight computational constraints, requires an efficient solution architecture. Efficiency requirements span from the distributed storage and large-scale organization of computation and data onto the lowest level of processor and data bus behavior. Integrating performance behavior over these levels is especially important when the computation is resource-bounded, as it is in numerics: physical simulation, machine learning, estimation of statistical models, etc. For example, memory locality and utilization of vector processing are essential for harnessing the computing power of modern processor architectures due to the deep memory hierarchies of modern general-purpose computers. As a r...

  8. Effects of traditional grammar teaching on standard six learners’ performance in understanding and using simple present tense, simple past tense, pronouns, and articles

    Directory of Open Access Journals (Sweden)

    Thulasimani Munohsamy

    2014-03-01

    Full Text Available This study sought to investigate whether there is any effect of the traditional grammar teaching on Standard Six learners’ performance in understanding and using simple present tense, simple past tense, pronouns and articles in writing. The sample for the study consisted of 40 Standard Six students of SK Tansau, Putatan, Kota Kinabalu, Sabah who was divided equally into two groups which were the treatment group and the control groups. Tests of understanding and of using the simple present tense, simple past tense, pronouns and articles were used as the instruments of the study. The data was collected through the administration of the pre-test and post-test. To analyze the collected data, the SPSS (Statistical Packages for Social Sciences version 11.5 was used. T-test was used to see if there was a significant difference in the mean of gain score. The Pearson Correlation was used on both tests between treatment group and control group to establish the relationship between scores on understanding and scores on using the grammatical features investigated. The study found that there was no significant difference in the mean of gain score in simple present tense, simple past tense and pronouns of the understanding test as well as writing test between the treatment and control groups. The results also indicated that there was no correlation between scores on test of understanding and test of using simple present tense, simple past tense, pronouns and articles on writing in the treatment group. There have been research studies in the past that lend clear cut support to the teaching of grammar as a mean of improving writing, however the results of this research clearly show that the implementation of Traditional Grammar Teaching has no effects on the students’ writing.

  9. Low-Cost High-Performance MRI

    Science.gov (United States)

    Sarracanie, Mathieu; Lapierre, Cristen D.; Salameh, Najat; Waddington, David E. J.; Witzel, Thomas; Rosen, Matthew S.

    2015-10-01

    Magnetic Resonance Imaging (MRI) is unparalleled in its ability to visualize anatomical structure and function non-invasively with high spatial and temporal resolution. Yet to overcome the low sensitivity inherent in inductive detection of weakly polarized nuclear spins, the vast majority of clinical MRI scanners employ superconducting magnets producing very high magnetic fields. Commonly found at 1.5-3 tesla (T), these powerful magnets are massive and have very strict infrastructure demands that preclude operation in many environments. MRI scanners are costly to purchase, site, and maintain, with the purchase price approaching $1 M per tesla (T) of magnetic field. We present here a remarkably simple, non-cryogenic approach to high-performance human MRI at ultra-low magnetic field, whereby modern under-sampling strategies are combined with fully-refocused dynamic spin control using steady-state free precession techniques. At 6.5 mT (more than 450 times lower than clinical MRI scanners) we demonstrate (2.5 × 3.5 × 8.5) mm3 imaging resolution in the living human brain using a simple, open-geometry electromagnet, with 3D image acquisition over the entire brain in 6 minutes. We contend that these practical ultra-low magnetic field implementations of MRI (standards for affordable (<$50,000) and robust portable devices.

  10. High school physics teacher forms of thought about simple electric circuits

    International Nuclear Information System (INIS)

    Kucukozer, H.

    2005-01-01

    According to some researches on students and on science teachers, they have same conceptual difficulties about simple electric circuits and these affect their further learning or/and teaching. [2], [5], [8], [9], [11], [13]. The main aim of this study was to investigate in-service high school physics teachers form of thought about simple electric circuits. In this purpose a test that was developed by Kucukozer [7], contains eight questions related to simple electric circuits was applied to in-service physics teachers (25 subjects) in various Anatolian Teacher High School in Turkey. After analyzing and evaluating of their data, it was found that, the physics teachers have conceptual difficulties about simple electric circuits, especially the concepts about source of stationary current and current usage

  11. Simple routine tests to improve the performance of the DPRSN TLD-based individual monitoring system

    International Nuclear Information System (INIS)

    Alves, J.G.; Batel, V.I.; Silva, P.B.; Roda, A.; Santos, L.

    2002-01-01

    This paper presents some of the results of a simple quality control program developed and implemented at the thermoluminescence sector of the IMS. The European Union (EU) Directive 96/29/EURATOM has not yet been transposed to national legislation and Portuguese law concerning the monitoring of radiation workers still establishes an annual dose limit of 50 mSv. However, new legislation has recently been published with requirements on the performance of dosimetric services. Some of the results of the tests reported herein will show compliance with the above mentioned requirements

  12. A Simple Analytic Model for Estimating Mars Ascent Vehicle Mass and Performance

    Science.gov (United States)

    Woolley, Ryan C.

    2014-01-01

    The Mars Ascent Vehicle (MAV) is a crucial component in any sample return campaign. In this paper we present a universal model for a two-stage MAV along with the analytic equations and simple parametric relationships necessary to quickly estimate MAV mass and performance. Ascent trajectories can be modeled as two-burn transfers from the surface with appropriate loss estimations for finite burns, steering, and drag. Minimizing lift-off mass is achieved by balancing optimized staging and an optimized path-to-orbit. This model allows designers to quickly find optimized solutions and to see the effects of design choices.

  13. Neo4j high performance

    CERN Document Server

    Raj, Sonal

    2015-01-01

    If you are a professional or enthusiast who has a basic understanding of graphs or has basic knowledge of Neo4j operations, this is the book for you. Although it is targeted at an advanced user base, this book can be used by beginners as it touches upon the basics. So, if you are passionate about taming complex data with the help of graphs and building high performance applications, you will be able to get valuable insights from this book.

  14. Use of simple transport equations to estimate waste package performance requirements

    International Nuclear Information System (INIS)

    Wood, B.J.

    1982-01-01

    A method of developing waste package performance requirements for specific nuclides is described. The method is based on: Federal regulations concerning permissible concentrations in solution at the point of discharge to the accessible environment; a simple and conservative transport model; baseline and potential worst-case release scenarios. Use of the transport model enables calculation of maximum permissible release rates within a repository in basalt for each of the scenarios. The maximum permissible release rates correspond to performance requirements for the engineered barrier system. The repository was assumed to be constructed in a basalt layer. For the cases considered, including a well drilled into an aquifer 1750 m from the repository center, little significant advantage is obtained from a 1000-yr as opposed to a 100-yr waste package. A 1000-yr waste package is of importance only for nuclides with half-lives much less than 100 yr which travel to the accessible environment in much less than 1000 yr. Such short travel times are extremely unlikely for a mined repository. Among the actinides, the most stringent maximum permissible release rates are for 236 U and 234 U. A simple solubility calculation suggests, however, that these performance requirements can be readily met by the engineered barrier system. Under the reducing conditions likely to occur in a repository located in basalt, uranium would be sufficiently insoluble that no solution could contain more than about 0.01% of the maximum permissible concentration at saturation. The performance requirements derived from the one-dimensional modeling approach are conservative by at least one to two orders of magnitude. More quantitative three-dimensional modeling at specific sites should enable relaxation of the performance criteria derived in this study. 12 references, 8 figures, 8 tables

  15. IMPLEMENTATION OF SIMPLE ADDITIVE WEIGHTING (SAW METHODE IN DETERMINING HIGH SCHOOL STUDENT’S INTEREST

    Directory of Open Access Journals (Sweden)

    Prind Triajeng Pungkasanti

    2017-09-01

    Full Text Available The Ministry of Research, Technology, and Higher Education of Republic of Indonesia has set a regulation about curriculum applied in education field named Kurikulum 2013. One of the subsections in the Kurikulum 2013 regulates all requirements of majoring in high school. High school students determine their major based on Kurrikulum 2013 as they are on the 10th grade. The purpose of the majoring in education is to allow children development based on their skills and interests, because before, majoring have been done based on scores obtained. The main problem is the majoring requirements considered are admission test score and Junior High School National Test score. Both scores are not sufficient enough to determine the students major therefore academic aptitude test score is required. In term of weighting, the school has not been imposed the weighting system so the scores obtained is the average of admission test score and national test score. Based on the issue above, a solution required to solve the issue using a method. Method used in this research is Simple Additive Weighting (SAW, wherein this methode is looking for the weighted sum of performance rate on every alternative of atributes. This research provides the information about which potential students is suitable to enter the science major and social major so this results can be used as consideration of school decisions.

  16. Development of a simple driving simulator and determination of the reference range of normative performance.

    Science.gov (United States)

    Kato, Noriaki; Saeki, Satoru; Okazaki, Tetsuya; Matsunaga, Katsuya; Hachisuka, Kenji

    2018-01-01

    To establish the reference range for assessment items of the 'Simple Driving Simulator' (SiDS) in a normative population and to compare performance of age-matched young adults with a traumatic brain injury (TBI) to this reference data. Normative ranges were calculated from the data of 445 participants in the control group. Three performance ranges were established: 'normal', 'borderline' and 'impaired' defined using standard deviation cutoff values in the control group. The performance of 28 patients with a TBI, aged 18-35 years, was evaluated. The performance score for the TBI group in the 'impaired range' was calculated for each test item and used to make a synthetic judgment regarding the clinical value of the SiDS. In the control group, only 0.6% of the participants exhibited a performance in the impaired range on >2 items, compared to 33.2% for the TBI group. We provide evidence that impaired performance on ≤2 items of the SiDS provides a sensitive criterion of 'driving fitness' in young adults after a TBI.

  17. High performance MEAs. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-15

    The aim of the present project is through modeling, material and process development to obtain significantly better MEA performance and to attain the technology necessary to fabricate stable catalyst materials thereby providing a viable alternative to current industry standard. This project primarily focused on the development and characterization of novel catalyst materials for the use in high temperature (HT) and low temperature (LT) proton-exchange membrane fuel cells (PEMFC). New catalysts are needed in order to improve fuel cell performance and reduce the cost of fuel cell systems. Additional tasks were the development of new, durable sealing materials to be used in PEMFC as well as the computational modeling of heat and mass transfer processes, predominantly in LT PEMFC, in order to improve fundamental understanding of the multi-phase flow issues and liquid water management in fuel cells. An improved fundamental understanding of these processes will lead to improved fuel cell performance and hence will also result in a reduced catalyst loading to achieve the same performance. The consortium have obtained significant research results and progress for new catalyst materials and substrates with promising enhanced performance and fabrication of the materials using novel methods. However, the new materials and synthesis methods explored are still in the early research and development phase. The project has contributed to improved MEA performance using less precious metal and has been demonstrated for both LT-PEM, DMFC and HT-PEM applications. New novel approach and progress of the modelling activities has been extremely satisfactory with numerous conference and journal publications along with two potential inventions concerning the catalyst layer. (LN)

  18. Fracture toughness of ultra high performance concrete by flexural performance

    Directory of Open Access Journals (Sweden)

    Manolova Emanuela

    2016-01-01

    Full Text Available This paper describes the fracture toughness of the innovative structural material - Ultra High Performance Concrete (UHPC, evaluated by flexural performance. For determination the material behaviour by static loading are used adapted standard test methods for flexural performance of fiber-reinforced concrete (ASTM C 1609 and ASTM C 1018. Fracture toughness is estimated by various deformation parameters derived from the load-deflection curve, obtained by testing simple supported beam under third-point loading, using servo-controlled testing system. This method is used to be estimated the contribution of the embedded fiber-reinforcement into improvement of the fractural behaviour of UHPC by changing the crack-resistant capacity, fracture toughness and energy absorption capacity with various mechanisms. The position of the first crack has been formulated based on P-δ (load- deflection response and P-ε (load - longitudinal deformation in the tensile zone response, which are used for calculation of the two toughness indices I5 and I10. The combination of steel fibres with different dimensions leads to a composite, having at the same time increased crack resistance, first crack formation, ductility and post-peak residual strength.

  19. Good distractions: Testing the effects of listening to an audiobook on driving performance in simple and complex road environments.

    Science.gov (United States)

    Nowosielski, Robert J; Trick, Lana M; Toxopeus, Ryan

    2018-02-01

    Distracted driving (driving while performing a secondary task) causes many collisions. Most research on distracted driving has focused on operating a cell-phone, but distracted driving can include eating while driving, conversing with passengers or listening to music or audiobooks. Although the research has focused on the deleterious effects of distraction, there may be situations where distraction improves driving performance. Fatigue and boredom are also associated with collision risk and it is possible that secondary tasks can help alleviate the effects of fatigue and boredom. Furthermore, it has been found that individuals with high levels of executive functioning as measured by the OSPAN (Operation Span) task show better driving while multitasking. In this study, licensed drivers were tested in a driving simulator (a car body surrounded by screens) that simulated simple or complex roads. Road complexity was manipulated by increasing traffic, scenery, and the number of curves in the drive. Participants either drove, or drove while listening to an audiobook. Driving performance was measured in terms of braking response time to hazards (HRT): the time required to brake in response to pedestrians or vehicles that suddenly emerged from the periphery into the path of the vehicle, speed, standard deviation of speed, standard deviation of lateral position (SDLP). Overall, braking times to hazards were higher on the complex drive than the simple one, though the effects of secondary tasks such as audiobooks were especially deleterious on the complex drive. In contrast, on the simple drive, driving while listening to an audiobook lead to faster HRT. We found evidence that individuals with high OSPAN scores had faster HRTs when listening to an audiobook. These results suggest that there are environmental and individual factors behind difference in the allocation of attention while listening to audiobooks while driving. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. High Performance Proactive Digital Forensics

    International Nuclear Information System (INIS)

    Alharbi, Soltan; Traore, Issa; Moa, Belaid; Weber-Jahnke, Jens

    2012-01-01

    With the increase in the number of digital crimes and in their sophistication, High Performance Computing (HPC) is becoming a must in Digital Forensics (DF). According to the FBI annual report, the size of data processed during the 2010 fiscal year reached 3,086 TB (compared to 2,334 TB in 2009) and the number of agencies that requested Regional Computer Forensics Laboratory assistance increasing from 689 in 2009 to 722 in 2010. Since most investigation tools are both I/O and CPU bound, the next-generation DF tools are required to be distributed and offer HPC capabilities. The need for HPC is even more evident in investigating crimes on clouds or when proactive DF analysis and on-site investigation, requiring semi-real time processing, are performed. Although overcoming the performance challenge is a major goal in DF, as far as we know, there is almost no research on HPC-DF except for few papers. As such, in this work, we extend our work on the need of a proactive system and present a high performance automated proactive digital forensic system. The most expensive phase of the system, namely proactive analysis and detection, uses a parallel extension of the iterative z algorithm. It also implements new parallel information-based outlier detection algorithms to proactively and forensically handle suspicious activities. To analyse a large number of targets and events and continuously do so (to capture the dynamics of the system), we rely on a multi-resolution approach to explore the digital forensic space. Data set from the Honeynet Forensic Challenge in 2001 is used to evaluate the system from DF and HPC perspectives.

  1. Ureteropelvic junction obstruction and ureteral strictures treated by simple high-pressure balloon dilation

    DEFF Research Database (Denmark)

    Osther, P J; Geertsen, U; Nielsen, H V

    1998-01-01

    The long-term results of simple high-pressure balloon dilation in the treatment of ureteropelvic junction obstruction (UPJO) and ureteral strictures were evaluated. A total of 77 consecutive patients were treated: 40 had UPJO and 37 ureteral strictures. The etiology of the obstruction included...... years, success was achieved in only 25% of cases. There were no major complications. It was concluded that simple high-pressure balloon dilation is a safe and reasonably effective technique for the management of most ureteral strictures and congenital UPJO with symptom debut in adult life. Balloon...

  2. Simple PVT quantitative method of Kr under high pure N2 condition

    International Nuclear Information System (INIS)

    Li Xuesong; Zhang Zibin; Wei Guanyi; Chen Liyun; Zhai Lihua

    2005-01-01

    A simple PVT quantitative method of Kr in the high pure N 2 was studied. Pressure, volume and temperature of the sample gas were measured by three individual methods to obtain the sum sample with food uncertainty. The ratio of Kr/N 2 could measured by GAM 400 quadrupole mass spectrometer. So the quantity of Kr could be calculated with the two measured data above. This method can be suited for quantitative analysis of other simple composed noble gas sample with high pure carrying gas. (authors)

  3. The reliability of test results from simple test samples in predicting the fatigue performance of automotive components

    International Nuclear Information System (INIS)

    Fourlaris, G.; Ellwood, R.; Jones, T.B.

    2007-01-01

    The use of high strength steels (HSS) in automotive components is steadily increasing as automotive designers use modern steel grades to improve structural performance, reduce vehicle weight and enhance crash performance. Weight reduction can be achieved by substituting mild steel with a thinner gauge HSS, however, it must be ensured that no deterioration in performance including fatigue capability occurs. In this study, tests have been carried out to determine the effects that gauge and material strength have on the fatigue performance of a fusion welded automotive suspension arm. Current finite element (FE) modelling and fatigue prediction techniques have been evaluated to determine their reliability when used for thin strip steels. Results have shown the fatigue performance of welded components to be independent of the strength of the parent material for the steel grades studied, with material thickness and joining process the key features determining the fatigue performance. The correlation between the fatigue performance of simple welded samples under uniaxial, constant amplitude loading and complex components under biaxial in service road load data, has been shown to be unreliable. This study also indicates that with the application of modern technologies, such as tailor-welded blanks (TWB), significant weight savings can be achieved. This is demonstrated by a 19% weight reduction with no detrimental effect on the fatigue performance

  4. Simple prognostic model for patients with advanced cancer based on performance status.

    Science.gov (United States)

    Jang, Raymond W; Caraiscos, Valerie B; Swami, Nadia; Banerjee, Subrata; Mak, Ernie; Kaya, Ebru; Rodin, Gary; Bryson, John; Ridley, Julia Z; Le, Lisa W; Zimmermann, Camilla

    2014-09-01

    Providing survival estimates is important for decision making in oncology care. The purpose of this study was to provide survival estimates for outpatients with advanced cancer, using the Eastern Cooperative Oncology Group (ECOG), Palliative Performance Scale (PPS), and Karnofsky Performance Status (KPS) scales, and to compare their ability to predict survival. ECOG, PPS, and KPS were completed by physicians for each new patient attending the Princess Margaret Cancer Centre outpatient Oncology Palliative Care Clinic (OPCC) from April 2007 to February 2010. Survival analysis was performed using the Kaplan-Meier method. The log-rank test for trend was employed to test for differences in survival curves for each level of performance status (PS), and the concordance index (C-statistic) was used to test the predictive discriminatory ability of each PS measure. Measures were completed for 1,655 patients. PS delineated survival well for all three scales according to the log-rank test for trend (P statistic was similar for all three scales and ranged from 0.63 to 0.64. We present a simple tool that uses PS alone to prognosticate in advanced cancer, and has similar discriminatory ability to more complex models. Copyright © 2014 by American Society of Clinical Oncology.

  5. High performance light water reactor

    International Nuclear Information System (INIS)

    Squarer, D.; Schulenberg, T.; Struwe, D.; Oka, Y.; Bittermann, D.; Aksan, N.; Maraczy, C.; Kyrki-Rajamaeki, R.; Souyri, A.; Dumaz, P.

    2003-01-01

    The objective of the high performance light water reactor (HPLWR) project is to assess the merit and economic feasibility of a high efficiency LWR operating at thermodynamically supercritical regime. An efficiency of approximately 44% is expected. To accomplish this objective, a highly qualified team of European research institutes and industrial partners together with the University of Tokyo is assessing the major issues pertaining to a new reactor concept, under the co-sponsorship of the European Commission. The assessment has emphasized the recent advancement achieved in this area by Japan. Additionally, it accounts for advanced European reactor design requirements, recent improvements, practical design aspects, availability of plant components and the availability of high temperature materials. The final objective of this project is to reach a conclusion on the potential of the HPLWR to help sustain the nuclear option, by supplying competitively priced electricity, as well as to continue the nuclear competence in LWR technology. The following is a brief summary of the main project achievements:-A state-of-the-art review of supercritical water-cooled reactors has been performed for the HPLWR project.-Extensive studies have been performed in the last 10 years by the University of Tokyo. Therefore, a 'reference design', developed by the University of Tokyo, was selected in order to assess the available technological tools (i.e. computer codes, analyses, advanced materials, water chemistry, etc.). Design data and results of the analysis were supplied by the University of Tokyo. A benchmark problem, based on the 'reference design' was defined for neutronics calculations and several partners of the HPLWR project carried out independent analyses. The results of these analyses, which in addition help to 'calibrate' the codes, have guided the assessment of the core and the design of an improved HPLWR fuel assembly. Preliminary selection was made for the HPLWR scale

  6. Quality assurance for high dose rate brachytherapy treatment planning optimization: using a simple optimization to verify a complex optimization

    International Nuclear Information System (INIS)

    Deufel, Christopher L; Furutani, Keith M

    2014-01-01

    As dose optimization for high dose rate brachytherapy becomes more complex, it becomes increasingly important to have a means of verifying that optimization results are reasonable. A method is presented for using a simple optimization as quality assurance for the more complex optimization algorithms typically found in commercial brachytherapy treatment planning systems. Quality assurance tests may be performed during commissioning, at regular intervals, and/or on a patient specific basis. A simple optimization method is provided that optimizes conformal target coverage using an exact, variance-based, algebraic approach. Metrics such as dose volume histogram, conformality index, and total reference air kerma agree closely between simple and complex optimizations for breast, cervix, prostate, and planar applicators. The simple optimization is shown to be a sensitive measure for identifying failures in a commercial treatment planning system that are possibly due to operator error or weaknesses in planning system optimization algorithms. Results from the simple optimization are surprisingly similar to the results from a more complex, commercial optimization for several clinical applications. This suggests that there are only modest gains to be made from making brachytherapy optimization more complex. The improvements expected from sophisticated linear optimizations, such as PARETO methods, will largely be in making systems more user friendly and efficient, rather than in finding dramatically better source strength distributions. (paper)

  7. Performance of semiconductor radiation sensors for simple and low-cost radiation detector

    International Nuclear Information System (INIS)

    Tanimura, Yoshihiko; Birumachi, Atsushi; Yoshida, Makoto; Watanabe, Tamaki

    2008-01-01

    In order to develop a simple but reliable radiation detector for the general public, photon detection performances of radiation sensors have been studied in photon calibration fields and by Monte Carlo simulations. A silicon p-i-n photodiode and a CdTe detector were selected for the low cost sensors. Their energy responses to ambient dose equivalent H * (10) were evaluated over the energy range from 60 keV to 2 MeV. The response of the CdTe decreases markedly with increasing photon energy. On the other hand, the photodiode has the advantage of almost flat response above 150 keV. The sensitivities of these sensors are 4 to 6 cpm for the natural radiation. Detection limits of the radiation level are low enough to know the extreme increase of radiation due to emergency situations of nuclear power plants, fuel treatment facilities and so on. (author)

  8. A simple vector system to improve performance and utilisation of recombinant antibodies

    Directory of Open Access Journals (Sweden)

    Vincent Karen J

    2006-12-01

    Full Text Available Abstract Background Isolation of recombinant antibody fragments from antibody libraries is well established using technologies such as phage display. Phage display vectors are ideal for efficient display of antibody fragments on the surface of bacteriophage particles. However, they are often inefficient for expression of soluble antibody fragments, and sub-cloning of selected antibody populations into dedicated soluble antibody fragment expression vectors can enhance expression. Results We have developed a simple vector system for expression, dimerisation and detection of recombinant antibody fragments in the form of single chain Fvs (scFvs. Expression is driven by the T7 RNA polymerase promoter in conjunction with the inducible lysogen strain BL21 (DE3. The system is compatible with a simple auto-induction culture system for scFv production. As an alternative to periplasmic expression, expression directly in the cytoplasm of a mutant strain with a more oxidising cytoplasmic environment (Origami 2™ (DE3 was investigated and found to be inferior to periplasmic expression in BL21 (DE3 cells. The effect on yield and binding activity of fusing scFvs to the N terminus of maltose binding protein (a solubility enhancing partner, bacterial alkaline phosphatase (a naturally dimeric enzymatic reporter molecule, or the addition of a free C-terminal cysteine was determined. Fusion of scFvs to the N-terminus of maltose binding protein increased scFv yield but binding activity of the scFv was compromised. In contrast, fusion to the N-terminus of bacterial alkaline phosphatase led to an improved performance. Alkaline phosphatase provides a convenient tag allowing direct enzymatic detection of scFv fusions within crude extracts without the need for secondary reagents. Alkaline phosphatase also drives dimerisation of the scFv leading to an improvement in performance compared to monovalent constructs. This is illustrated by ELISA, western blot and

  9. Simple heuristic derivation of some charge-transfer probabilities at asymptotically high incident velocities

    International Nuclear Information System (INIS)

    Spruch, L.; Shakeshaft, R.

    1984-01-01

    For asymptotically high incident velocities we provide simple, heuristic, almost classical, derivations of the cross section for forward charge transfer, and of the ratio of the cross section for capture to the elastic-scattering cross section for the projectile scattered through an angle close to π/3

  10. Two simple ansaetze for obtaining exact solutions of high dispersive nonlinear Schroedinger equations

    International Nuclear Information System (INIS)

    Palacios, Sergio L.

    2004-01-01

    We propose two simple ansaetze that allow us to obtain different analytical solutions of the high dispersive cubic and cubic-quintic nonlinear Schroedinger equations. Among these solutions we can find solitary wave and periodic wave solutions representing the propagation of different waveforms in nonlinear media

  11. Development of high performance cladding

    International Nuclear Information System (INIS)

    Kiuchi, Kiyoshi

    2003-01-01

    The developments of superior next-generation light water reactor are requested on the basis of general view points, such as improvement of safety, economics, reduction of radiation waste and effective utilization of plutonium, until 2030 year in which conventional reactor plants should be renovate. Improvements of stainless steel cladding for conventional high burn-up reactor to more than 100 GWd/t, developments of manufacturing technology for reduced moderation-light water reactor (RMWR) of breeding ratio beyond 1.0 and researches of water-materials interaction on super critical pressure-water cooled reactor are carried out in Japan Atomic Energy Research Institute. Stable austenite stainless steel has been selected for fuel element cladding of advanced boiling water reactor (ABWR). The austenite stain less has the superiority for anti-irradiation properties, corrosion resistance and mechanical strength. A hard spectrum of neutron energy up above 0.1 MeV takes place in core of the reduced moderation-light water reactor, as liquid metal-fast breeding reactor (LMFBR). High performance cladding for the RMWR fuel elements is required to get anti-irradiation properties, corrosion resistance and mechanical strength also. Slow strain rate test (SSRT) of SUS 304 and SUS 316 are carried out for studying stress corrosion cracking (SCC). Irradiation tests in LMFBR are intended to obtain irradiation data for damaged quantity of the cladding materials. (M. Suetake)

  12. High precision simple interpolation asynchronous FIFO based on ACEX1K30 for HIRFL-CSRe

    International Nuclear Information System (INIS)

    Li Guihua; Qiao Weimin; Jing Lan

    2008-01-01

    High precision simple interpolation asynchronous FIFO of HIRFL-CSRe was developed based on the ACEX1K30 FPGA in VHDL Hardware Description language. The FIFO runs in FPGA of DSP module of HIRFL-CSRe. The input data of FIFO is from DSP data bus and the output data is to DAC data bus. It's kernel adopts double buffer ping-pong mode and it can implement simple interpolation inside FPGA. The module can control out- put data time delay in 40 ns. The experimental results indicate that this module is practical and accurate to HIRFL-CSRe. (authors)

  13. Uniting Evidence-Based Evaluation with the ACGME Plastic Surgery Milestones: A Simple and Reliable Assessment of Resident Operative Performance.

    Science.gov (United States)

    Kobraei, Edward M; Bohnen, Jordan D; George, Brian C; Mullen, John T; Lillemoe, Keith D; Austen, William G; Liao, Eric C

    2016-08-01

    Milestones evaluations in plastic surgery reflect a shift toward competency-based training but have created a number of challenges. The authors have incorporated the smartphone application evaluation tool, System for Improving and Measuring Procedural Learning (SIMPL), that was recently developed by a multi-institutional research collaborative. In this pilot study, the authors hypothesize that SIMPL can improve resident evaluation and also collect granular performance data to simplify compliance with the plastic surgery Milestones. SIMPL was prospectively piloted with a plastic surgery resident and faculty surgeon at Massachusetts General Hospital in this institutional review board-approved study. The study period was a 2-month interval corresponding to the resident's rotation. The resident-faculty combination performed 20 cases together. All cases were evaluated with SIMPL. SIMPL evaluations uniformly took under 1 minute to submit. The average time to completed evaluation from surgery completion was 5 hours (technology will support a shared vocabulary between residents and faculty to enhance intraoperative education.

  14. A Simple Semaphore Signaling Technique for Ultra-High Frequency Spacecraft Communications

    Science.gov (United States)

    Butman, S.; Satorius, E.; Illott, P.

    2005-11-01

    For planetary lander missions such as the upcoming Phoenix mission to Mars, the most challenging phase of the spacecraft-to-ground communications is during the critical phase termed entry, descent, and landing (EDL). At 8.4 GHz (X-band), the signals received by the largest Deep Space Network (DSN) antennas can be too weak for even 1 bit per second (bps) and therefore not able to communicate critical information to Earth. Fortunately, the lander's ultra-high frequency (UHF) link to an orbiting relay can meet the EDL requirements, but the data rate needs to be low enough to fit the capability of the UHF link during some or all of EDL. On Phoenix, the minimum data rate of the as-built UHF radio is 8 kbps and requires a signal level at the Odyssey orbiter of at least minus 120 dBm. For lower signaling levels, the effective data rate needs to be reduced, but without incurring the cost of rebuilding and requalifying the equipment. To address this scenario, a simple form of frequency-shift keying (FSK) has been devised by appropriately programming the data stream that is input to the UHF transceiver. This article describes this technique and provides performance estimates. Laboratory testing reveals that input signal levels at minus 140 dBm and lower can routinely be demodulated with the proposed signaling scheme, thereby providing a 20-dB and greater margin over the 8-kbps threshold.

  15. Simple Exact Algorithm for Transistor Sizing of Low-Power High-Speed Arithmetic Circuits

    Directory of Open Access Journals (Sweden)

    Tooraj Nikoubin

    2010-01-01

    Full Text Available A new transistor sizing algorithm, SEA (Simple Exact Algorithm, for optimizing low-power and high-speed arithmetic integrated circuits is proposed. In comparison with other transistor sizing algorithms, simplicity, accuracy, independency of order and initial sizing factors of transistors, and flexibility in choosing the optimization parameters such as power consumption, delay, Power-Delay Product (PDP, chip area or the combination of them are considered as the advantages of this new algorithm. More exhaustive rules of grouping transistors are the main trait of our algorithm. Hence, the SEA algorithm dominates some major transistor sizing metrics such as optimization rate, simulation speed, and reliability. According to approximate comparison of the SEA algorithm with MDE and ADC for a number of conventional full adder circuits, delay and PDP have been improved 55.01% and 57.92% on an average, respectively. By comparing the SEA and Chang's algorithm, 25.64% improvement in PDP and 33.16% improvement in delay have been achieved. All the simulations have been performed with 0.13 m technology based on the BSIM3v3 model using HSpice simulator software.

  16. Simple Fourier optics formalism for high-angular-resolution systems and nulling interferometry.

    Science.gov (United States)

    Hénault, François

    2010-03-01

    Reviewed are various designs of advanced, multiaperture optical systems dedicated to high-angular-resolution imaging or to the detection of exoplanets by nulling interferometry. A simple Fourier optics formalism applicable to both imaging arrays and nulling interferometers is presented, allowing their basic theoretical relationships to be derived as convolution or cross-correlation products suitable for fast and accurate computation. Several unusual designs, such as a "superresolving telescope" utilizing a mosaicking observation procedure or a free-flying, axially recombined interferometer are examined, and their performance in terms of imaging and nulling capacity are assessed. In all considered cases, it is found that the limiting parameter is the diameter of the individual telescopes. A final section devoted to nulling interferometry shows an apparent superiority of axial versus multiaxial recombining schemes. The entire study is valid only in the framework of first-order geometrical optics and scalar diffraction theory. Furthermore, it is assumed that all entrance subapertures are optically conjugated with their associated exit pupils.

  17. Investigations on self-starting and performance characteristics of simple H and hybrid H-Savonius vertical axis wind rotors

    International Nuclear Information System (INIS)

    Bhuyan, S.; Biswas, A.

    2014-01-01

    Highlights: • Hybrid H-Savonius vertical axis wind rotor for built-in environmental wind speeds. • Self-starting characteristics of unsymmetrical H-rotor and Hybrid H-Savonius rotor. • Comparisons between unsymmetrical H-rotor and Hybrid rotor at same experimental conditions. • Insight of the performances of optimum hybrid H-Savonius rotor. • Higher power performance of the optimum rotor compared with some existing VAWT rotors. - Abstract: With recent surge in fossil fuel prices and demands for renewable energy sources, vertical axis wind turbine (VAWT) technologies have emerged out as one of the prime growing sector for small-scale power generation in the built environment. In such an environment, self-starting and high performances are of utmost importance. Amongst all VAWT designs, H-rotor, being a lift-driven device, exhibits a high power coefficient. However, it suffers from poor starting behavior due to its conventional symmetrical NACA airfoil blades. The objective of the present study is to design a VAWT rotor that possesses both self-starting and high power coefficient simultaneously. For this, a three bladed H-rotor with unsymmetrical cambered S818 airfoil blades is investigated, which shows self-starting characteristics at many of the azimuthal angles. However to make the rotor completely self-starting, the same H-rotor is incorporated in a hybrid system with Savonius rotor as its starter. It is found that the hybrid design fully exhibits self-starting capability at all azimuthal positions, signified by the positive static torque coefficient values. For improving power performance of the hybrid rotor, the same is subjected to rigorous experimentations on the wind tunnel at different Reynolds numbers (Re) between 1.44 × 10 5 and 2.31 × 10 5 for five different overlap conditions in the Savonius rotor part. The performance coefficients of the hybrid rotor are compared with the simple H-rotor. Out of all the designs investigated, the maximum Cp

  18. The Influence of Different Performance Level of Fencers on Simple and Choice Reaction Time

    Directory of Open Access Journals (Sweden)

    Štefan Balkó

    2016-09-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2016v18n4p391   In many sport disciplines reaction time plays a key role in the sport performance. It is good to point out for example ball games or fighting sports (fencing, karate etc.. The research is focused on detection of the differences in the simple and choice reaction time during visual stimulation among elite, sub-elite fencers and beginners. For the measurement a Fitrosword device and the SWORD software were used. An additional stimulus was added during measuring which should increase the overall number of stimuli, but shouldn’t force fencer to any reaction whatsoever. The results from presented study can be compared with Hicks law. The next focus of the study was to identify the difference in reaction time during two different movement tasks with different complexity movement requirements. The research was built up on a hypothesis that the results will differ among different performance groups of fencers. The difference however was overt among beginners and elite fencers (p = 0.0088, d = 0.5 in reaction time during different movement tasks (direct hit vs. lunge. The results of this research could be useful to trainers for training process organisation and increase the effectivity of muscle coordination during several movements in fencing.

  19. Comparison of simple additive weighting (SAW) and composite performance index (CPI) methods in employee remuneration determination

    Science.gov (United States)

    Karlitasari, L.; Suhartini, D.; Benny

    2017-01-01

    The process of determining the employee remuneration for PT Sepatu Mas Idaman currently are still using Microsoft Excel-based spreadsheet where in the spreadsheet there is the value of criterias that must be calculated for every employee. This can give the effect of doubt during the assesment process, therefore resulting in the process to take much longer time. The process of employee remuneration determination is conducted by the assesment team based on some criterias that have been predetermined. The criteria used in the assessment process are namely the ability to work, human relations, job responsibility, discipline, creativity, work, achievement of targets, and absence. To ease the determination of employee remuneration to be more efficient and effective, the Simple Additive Weighting (SAW) method is used. SAW method can help in decision making for a certain case, and the calculation that generates the greatest value will be chosen as the best alternative. Other than SAW, also by using another method was the CPI method which is one of the calculating method in decision making based on performance index. Where SAW method was more faster by 89-93% compared to CPI method. Therefore it is expected that this application can be an evaluation material for the need of training and development for employee performances to be more optimal.

  20. Evaluation of radiation shielding performance in sea transport of radioactive material by using simple calculation method

    International Nuclear Information System (INIS)

    Odano, N.; Ohnishi, S.; Sawamura, H.; Tanaka, Y.; Nishimura, K.

    2004-01-01

    A modified code system based on the point kernel method was developed to use in evaluation of shielding performance for maritime transport of radioactive material. For evaluation of shielding performance accurately in the case of accident, it is required to preciously model the structure of transport casks and shipping vessel, and source term. To achieve accurate modelling of the geometry and source term condition, we aimed to develop the code system by using equivalent information regarding structure and source term used in the Monte Carlo calculation code, MCNP. Therefore, adding an option to use point kernel method to the existing Monte Carlo code, MCNP4C, the code system was developed. To verify the developed code system, dose rate distribution in an exclusive shipping vessel to transport the low level radioactive wastes were calculated by the developed code and the calculated results were compared with measurements and Monte Carlo calculations. It was confirmed that the developed simple calculation method can obtain calculation results very quickly with enough accuracy comparing with the Monte Carlo calculation code MCNP4C

  1. Development of student performance assessment based on scientific approach for a basic physics practicum in simple harmonic motion materials

    Science.gov (United States)

    Serevina, V.; Muliyati, D.

    2018-05-01

    This research aims to develop students’ performance assessment instrument based on scientific approach is valid and reliable in assessing the performance of students on basic physics lab of Simple Harmonic Motion (SHM). This study uses the ADDIE consisting of stages: Analyze, Design, Development, Implementation, and Evaluation. The student performance assessment developed can be used to measure students’ skills in observing, asking, conducting experiments, associating and communicate experimental results that are the ‘5M’ stages in a scientific approach. Each grain of assessment in the instrument is validated by the instrument expert and the evaluation with the result of all points of assessment shall be eligible to be used with a 100% eligibility percentage. The instrument is then tested for the quality of construction, material, and language by panel (lecturer) with the result: 85% or very good instrument construction aspect, material aspect 87.5% or very good, and language aspect 83% or very good. For small group trial obtained instrument reliability level of 0.878 or is in the high category, where r-table is 0.707. For large group trial obtained instrument reliability level of 0.889 or is in the high category, where r-table is 0.320. Instruments declared valid and reliable for 5% significance level. Based on the result of this research, it can be concluded that the student performance appraisal instrument based on the developed scientific approach is declared valid and reliable to be used in assessing student skill in SHM experimental activity.

  2. Determination of Caffeine in Beverages by High Performance Liquid Chromatography.

    Science.gov (United States)

    DiNunzio, James E.

    1985-01-01

    Describes the equipment, procedures, and results for the determination of caffeine in beverages by high performance liquid chromatography. The method is simple, fast, accurate, and, because sample preparation is minimal, it is well suited for use in a teaching laboratory. (JN)

  3. Development and validation of a reversed phase High Performance ...

    African Journals Online (AJOL)

    A simple, rapid, accurate and economical isocratic Reversed Phase High Performance Liquid Chromatography (RPHPLC) method was developed, validated and used for the evaluation of content of different brands of paracetamol tablets. The method was validated according to ICH guidelines and may be adopted for the ...

  4. Buffer-Free High Performance Liquid Chromatography Method for ...

    African Journals Online (AJOL)

    Purpose: To develop and validate a simple, economical and reproducible high performance liquid chromatographic (HPLC) method for the determination of theophylline in pharmaceutical dosage forms. Method: Caffeine was used as the internal standard and reversed phase C-18 column was used to elute the drug and ...

  5. Bench tests of simple, handy ventilators for pandemics: performance, autonomy, and ergonomy.

    Science.gov (United States)

    L'Her, Erwan; Roy, Annie

    2011-06-01

    It has been pointed out that in the wake of a virulent flu strain, patients with survivable illness will die from lack of resources unless more ventilators are made available. Numerous disaster-type ventilators are available, but few evaluations have been performed. To compare simple, lightweight, and handy ventilators that could be used in the initial care of patients with respiratory distress. We bench-tested 4 volume-cycled ventilators (Carevent ALS, EPV100, Pneupac VR1, and Medumat Easy) and 2 pressure-cycled ventilators (Oxylator EMX and VAR-Plus). We studied their general physical characteristics, sonometry, gas consumption, technical performance, ergonomy, and user-friendliness. With a test lung we assessed performance at F(IO(2)) of 0.50 and 1.0, set compliance of 30, 70, and 120 mL/cm H(2)O, and set resistance of 5, 10, and 20 cm H(2)O/L/s. To study user-friendliness and ergonomy we conducted, in randomized order, 7 or 8 objective, quantitative tests and 2 subjective tests. Compliance and resistance strongly affected tidal volume with the pressure-cycled ventilators (from 418 ± 49 mL to 1,377 ± 444 mL with the VAR-Plus, at the lowest pressure level), whereas the volume-cycled ventilators provided a consistent tidal volume in the face of changing test lung characteristics. We are concerned that the pressure-cycled ventilators did not provide a consistent tidal volume, and under certain conditions the volume delivered would be unsafe (too large or too small). Most of the volume-cycled ventilators proved to be technically efficient and reliable. Their reliability, portability, and ease of use could make them valuable in natural disasters and mass-casualty events.

  6. SPARTAN: a simple performance assessment code for the Nevada Nuclear Waste Storage Investigations Project

    International Nuclear Information System (INIS)

    Lin, Y.T.

    1985-12-01

    SPARTAN is a simple computer model designed for the Nevada Nuclear Waste Storage Investigations Project to calculate radionuclide transport in geologic media. The physical processes considered are limited to Darcy's flow, radionuclide decay, and convective transport with constant retardation of radionuclides relative to water flow. Inputs for the model must be provided for the geometry, repository area, flow path, water flux, effective porosity, initial inventory, waste solubility, canister lifetime, and retardation factors. Results from the model consist of radionuclide release rates from the prospective Yucca Mountain repository for radioactive waste and cumulative curies released across the flow boundaries at the end of the flow path. The rates of release from the repository relative to NRC performance objectives and releases to the accessible environment relative to EPA requirements are also calculated. Two test problems compare the results of simulations from SPARTAN with analytical solutions. The comparisons show that the SPARTAN solution closely matches the analytical solutions across a range of conditions that approximate those that might occur at Yucca Mountain

  7. A simple optimization can improve the performance of single feature polymorphism detection by Affymetrix expression arrays

    Directory of Open Access Journals (Sweden)

    Fujisawa Hironori

    2010-05-01

    Full Text Available Abstract Background High-density oligonucleotide arrays are effective tools for genotyping numerous loci simultaneously. In small genome species (genome size: Results We compared the single feature polymorphism (SFP detection performance of whole-genome and transcript hybridizations using the Affymetrix GeneChip® Rice Genome Array, using the rice cultivars with full genome sequence, japonica cultivar Nipponbare and indica cultivar 93-11. Both genomes were surveyed for all probe target sequences. Only completely matched 25-mer single copy probes of the Nipponbare genome were extracted, and SFPs between them and 93-11 sequences were predicted. We investigated optimum conditions for SFP detection in both whole genome and transcript hybridization using differences between perfect match and mismatch probe intensities of non-polymorphic targets, assuming that these differences are representative of those between mismatch and perfect targets. Several statistical methods of SFP detection by whole-genome hybridization were compared under the optimized conditions. Causes of false positives and negatives in SFP detection in both types of hybridization were investigated. Conclusions The optimizations allowed a more than 20% increase in true SFP detection in whole-genome hybridization and a large improvement of SFP detection performance in transcript hybridization. Significance analysis of the microarray for log-transformed raw intensities of PM probes gave the best performance in whole genome hybridization, and 22,936 true SFPs were detected with 23.58% false positives by whole genome hybridization. For transcript hybridization, stable SFP detection was achieved for highly expressed genes, and about 3,500 SFPs were detected at a high sensitivity (> 50% in both shoot and young panicle transcripts. High SFP detection performances of both genome and transcript hybridizations indicated that microarrays of a complex genome (e.g., of Oryza sativa can be

  8. Learning Apache Solr high performance

    CERN Document Server

    Mohan, Surendra

    2014-01-01

    This book is an easy-to-follow guide, full of hands-on, real-world examples. Each topic is explained and demonstrated in a specific and user-friendly flow, from search optimization using Solr to Deployment of Zookeeper applications. This book is ideal for Apache Solr developers and want to learn different techniques to optimize Solr performance with utmost efficiency, along with effectively troubleshooting the problems that usually occur while trying to boost performance. Familiarity with search servers and database querying is expected.

  9. High-performance composite chocolate

    Science.gov (United States)

    Dean, Julian; Thomson, Katrin; Hollands, Lisa; Bates, Joanna; Carter, Melvyn; Freeman, Colin; Kapranos, Plato; Goodall, Russell

    2013-07-01

    The performance of any engineering component depends on and is limited by the properties of the material from which it is fabricated. It is crucial for engineering students to understand these material properties, interpret them and select the right material for the right application. In this paper we present a new method to engage students with the material selection process. In a competition-based practical, first-year undergraduate students design, cost and cast composite chocolate samples to maximize a particular performance criterion. The same activity could be adapted for any level of education to introduce the subject of materials properties and their effects on the material chosen for specific applications.

  10. A simple two-step method to fabricate highly transparent ITO/polymer nanocomposite films

    International Nuclear Information System (INIS)

    Liu, Haitao; Zeng, Xiaofei; Kong, Xiangrong; Bian, Shuguang; Chen, Jianfeng

    2012-01-01

    Highlights: ► A simple two-step method without further surface modification step was employed. ► ITO nanoparticles were easily to be uniformly dispersed in polymer matrix. ► ITO/polymer nanocomposite film had high transparency and UV/IR blocking properties. - Abstract: Transparent functional indium tin oxide (ITO)/polymer nanocomposite films were fabricated via a simple approach with two steps. Firstly, the functional monodisperse ITO nanoparticles were synthesized via a facile nonaqueous solvothermal method using bifunctional chemical agent (N-methyl-pyrrolidone, NMP) as the reaction solvent and surface modifier. Secondly, the ITO/acrylics polyurethane (PUA) nanocomposite films were fabricated by a simple sol-solution mixing method without any further surface modification step as often employed traditionally. Flower-like ITO nanoclusters with about 45 nm in diameter were mono-dispersed in ethyl acetate and each nanocluster was assembled by nearly spherical nanoparticles with primary size of 7–9 nm in diameter. The ITO nanoclusters exhibited an excellent dispersibility in polymer matrix of PUA, remaining their original size without any further agglomeration. When the loading content of ITO nanoclusters reached to 5 wt%, the transparent functional nanocomposite film featured a high transparency more than 85% in the visible light region (at 550 nm), meanwhile cutting off near-infrared radiation about 50% at 1500 nm and blocking UV ray about 45% at 350 nm. It could be potential for transparent functional coating materials applications.

  11. Simple laser-driven, metal photocathodes as cold, high-current electron sources

    International Nuclear Information System (INIS)

    Saunders, J.D.; Ringler, T.J.; Builta, L.A.; Kauppila, T.J.; Moir, D.C.; Downey, S.W.

    1987-01-01

    Recent developments in excimer laser design have made near ultraviolet light intensities of several MWcm 2 possible in unfocused beams. These advances and recent experiments indicate that high-current, simple-metal photoemissive electron guns are now feasible. Producing more than 50 Acm 2 of illuminated cathode surface, the guns could operate at vacuums of 10 -6 torr with no complicated system components inside the vacuum enclosure. The electron beam produced by such photoemission guns would have very low emittance and high brightness. This beam would also closely follow the temporal characteristics of the laser pulse, making fast risetime, ultrashort electron beam pulses possible

  12. Highly Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to Simple Aryl Ketones: Efficient Synthesis of Escitalopram.

    Science.gov (United States)

    Huang, Linwei; Zhu, Jinbin; Jiao, Guangjun; Wang, Zheng; Yu, Xingxin; Deng, Wei-Ping; Tang, Wenjun

    2016-03-24

    Highly enantioselective additions of arylboroxines to simple aryl ketones have been achieved for the first time with a Rh/(R,R,R,R)-WingPhos catalyst, thus providing a range of chiral diaryl alkyl carbinols with excellent ee values and yields. (R,R,R,R)-WingPhos has been proven to be crucial for the high reactivity and enantioselectivity. The method has enabled a new, concise, and enantioselective synthesis of the antidepressant drug escitalopram. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Stretchable and High-Performance Supercapacitors with Crumpled Graphene Papers

    OpenAIRE

    Zang, Jianfeng; Cao, Changyong; Feng, Yaying; Liu, Jie; Zhao, Xuanhe

    2014-01-01

    Fabrication of unconventional energy storage devices with high stretchability and performance is challenging, but critical to practical operations of fully power-independent stretchable electronics. While supercapacitors represent a promising candidate for unconventional energy-storage devices, existing stretchable supercapacitors are limited by their low stretchability, complicated fabrication process, and high cost. Here, we report a simple and low-cost method to fabricate extremely stretch...

  14. High-Performance Composite Chocolate

    Science.gov (United States)

    Dean, Julian; Thomson, Katrin; Hollands, Lisa; Bates, Joanna; Carter, Melvyn; Freeman, Colin; Kapranos, Plato; Goodall, Russell

    2013-01-01

    The performance of any engineering component depends on and is limited by the properties of the material from which it is fabricated. It is crucial for engineering students to understand these material properties, interpret them and select the right material for the right application. In this paper we present a new method to engage students with…

  15. Toward High-Performance Organizations.

    Science.gov (United States)

    Lawler, Edward E., III

    2002-01-01

    Reviews management changes that companies have made over time in adopting or adapting four approaches to organizational performance: employee involvement, total quality management, re-engineering, and knowledge management. Considers future possibilities and defines a new view of what constitutes effective organizational design in management.…

  16. High-Performance Wireless Telemetry

    Science.gov (United States)

    Griebeler, Elmer; Nawash, Nuha; Buckley, James

    2011-01-01

    Prior technology for machinery data acquisition used slip rings, FM radio communication, or non-real-time digital communication. Slip rings are often noisy, require much space that may not be available, and require access to the shaft, which may not be possible. FM radio is not accurate or stable, and is limited in the number of channels, often with channel crosstalk, and intermittent as the shaft rotates. Non-real-time digital communication is very popular, but complex, with long development time, and objections from users who need continuous waveforms from many channels. This innovation extends the amount of information conveyed from a rotating machine to a data acquisition system while keeping the development time short and keeping the rotating electronics simple, compact, stable, and rugged. The data are all real time. The product of the number of channels, times the bit resolution, times the update rate, gives a data rate higher than available by older methods. The telemetry system consists of a data-receiving rack that supplies magnetically coupled power to a rotating instrument amplifier ring in the machine being monitored. The ring digitizes the data and magnetically couples the data back to the rack, where it is made available. The transformer is generally a ring positioned around the axis of rotation with one side of the transformer free to rotate and the other side held stationary. The windings are laid in the ring; this gives the data immunity to any rotation that may occur. A medium-frequency sine-wave power source in a rack supplies power through a cable to a rotating ring transformer that passes the power on to a rotating set of electronics. The electronics power a set of up to 40 sensors and provides instrument amplifiers for the sensors. The outputs from the amplifiers are filtered and multiplexed into a serial ADC. The output from the ADC is connected to another rotating ring transformer that conveys the serial data from the rotating section to

  17. Functional High Performance Financial IT

    DEFF Research Database (Denmark)

    Berthold, Jost; Filinski, Andrzej; Henglein, Fritz

    2011-01-01

    at the University of Copenhagen that attacks this triple challenge of increased performance, transparency and productivity in the financial sector by a novel integration of financial mathematics, domain-specific language technology, parallel functional programming, and emerging massively parallel hardware. HIPERFIT......The world of finance faces the computational performance challenge of massively expanding data volumes, extreme response time requirements, and compute-intensive complex (risk) analyses. Simultaneously, new international regulatory rules require considerably more transparency and external...... auditability of financial institutions, including their software systems. To top it off, increased product variety and customisation necessitates shorter software development cycles and higher development productivity. In this paper, we report about HIPERFIT, a recently etablished strategic research center...

  18. High performance Mo adsorbent PZC

    Energy Technology Data Exchange (ETDEWEB)

    Anon,

    1998-10-01

    We have developed Mo adsorbents for natural Mo(n, {gamma}){sup 99}Mo-{sup 99m}Tc generator. Among them, we called the highest performance adsorbent PZC that could adsorb about 250 mg-Mo/g. In this report, we will show the structure, adsorption mechanism of Mo, and the other useful properties of PZC when you carry out the examination of Mo adsorption and elution of {sup 99m}Tc. (author)

  19. Indoor Air Quality in High Performance Schools

    Science.gov (United States)

    High performance schools are facilities that improve the learning environment while saving energy, resources, and money. The key is understanding the lifetime value of high performance schools and effectively managing priorities, time, and budget.

  20. Enabling People with Developmental Disabilities to Actively Follow Simple Instructions and Perform Designated Physical Activities According to Simple Instructions with Nintendo Wii Balance Boards by Controlling Environmental Stimulation

    Science.gov (United States)

    Shih, Ching-Hsiang; Chung, Chiao-Chen; Shih, Ching-Tien; Chen, Ling-Che

    2011-01-01

    The latest researches have adopted software technology turning the Nintendo Wii Balance Board into a high performance standing location detector. This study extended Wii Balance Board functionality to assess whether two people with developmental disabilities would be able to actively perform designated physical activities according to simple…

  1. High performance inertial fusion targets

    International Nuclear Information System (INIS)

    Nuckolls, J.H.; Bangerter, R.O.; Lindl, J.D.; Mead, W.C.; Pan, Y.L.

    1977-01-01

    Inertial confinement fusion (ICF) designs are considered which may have very high gains (approximately 1000) and low power requirements (<100 TW) for input energies of approximately one megajoule. These include targets having very low density shells, ultra thin shells, central ignitors, magnetic insulation, and non-ablative acceleration

  2. High performance inertial fusion targets

    International Nuclear Information System (INIS)

    Nuckolls, J.H.; Bangerter, R.O.; Lindl, J.D.; Mead, W.C.; Pan, Y.L.

    1978-01-01

    Inertial confinement fusion (ICF) target designs are considered which may have very high gains (approximately 1000) and low power requirements (< 100 TW) for input energies of approximately one megajoule. These include targets having very low density shells, ultra thin shells, central ignitors, magnetic insulation, and non-ablative acceleration

  3. High performance nuclear fuel element

    International Nuclear Information System (INIS)

    Mordarski, W.J.; Zegler, S.T.

    1980-01-01

    A fuel-pellet composition is disclosed for use in fast breeder reactors. Uranium carbide particles are mixed with a powder of uraniumplutonium carbides having a stable microstructure. The resulting mixture is formed into fuel pellets. The pellets thus produced exhibit a relatively low propensity to swell while maintaining a high density

  4. High Performance JavaScript

    CERN Document Server

    Zakas, Nicholas

    2010-01-01

    If you're like most developers, you rely heavily on JavaScript to build interactive and quick-responding web applications. The problem is that all of those lines of JavaScript code can slow down your apps. This book reveals techniques and strategies to help you eliminate performance bottlenecks during development. You'll learn how to improve execution time, downloading, interaction with the DOM, page life cycle, and more. Yahoo! frontend engineer Nicholas C. Zakas and five other JavaScript experts -- Ross Harmes, Julien Lecomte, Steven Levithan, Stoyan Stefanov, and Matt Sweeney -- demonstra

  5. A simple identification method for spore-forming bacteria showing high resistance against γ-rays

    International Nuclear Information System (INIS)

    Koshikawa, Tomihiko; Sone, Koji; Kobayashi, Toshikazu

    1993-01-01

    A simple identification method was developed for spore-forming bacteria which are highly resistant against γ-rays. Among 23 species of Bacillus studied, the spores of Bacillus megaterium, B. cereus, B. thuringiensis, B. pumilus and B. aneurinolyticus showed high resistance against γ-rays as compared with other spores of Bacillus species. Combination of the seven kinds of biochemical tests, namely, the citrate utilization test, nitrate reduction test, starch hydrolysis test, Voges-Proskauer reaction test, gelatine hydrolysis test, mannitol utilization test and xylose utilization test showed a characteristic pattern for each species of Bacillus. The combination pattern of each the above tests with a few supplementary test, if necessary, was useful to identify Bacillus species showing high radiation resistance against γ-rays. The method is specific for B. megaterium, B. thuringiensis and B. pumilus, and highly selective for B. aneurinolyticus and B. cereus. (author)

  6. Carpet Aids Learning in High Performance Schools

    Science.gov (United States)

    Hurd, Frank

    2009-01-01

    The Healthy and High Performance Schools Act of 2002 has set specific federal guidelines for school design, and developed a federal/state partnership program to assist local districts in their school planning. According to the Collaborative for High Performance Schools (CHPS), high-performance schools are, among other things, healthy, comfortable,…

  7. High-Performance Liquid Chromatography in the Undergraduate Chemical Engineering Laboratory

    Science.gov (United States)

    Frey, Douglas D.; Guo, Hui; Karnik, Nikhila

    2013-01-01

    This article describes the assembly of a simple, low-cost, high-performance liquid chromatography (HPLC) system and its use in the undergraduate chemical engineering laboratory course to perform simple experiments. By interpreting the results from these experiments students are able to gain significant experience in the general method of…

  8. Simple single-emitting layer hybrid white organic light emitting with high color stability

    Science.gov (United States)

    Nguyen, C.; Lu, Z. H.

    2017-10-01

    Simultaneously achieving a high efficiency and color quality at luminance levels required for solid-state lighting has been difficult for white organic light emitting diodes (OLEDs). Single-emitting layer (SEL) white OLEDs, in particular, exhibit a significant tradeoff between efficiency and color stability. Furthermore, despite the simplicity of SEL white OLEDs being its main advantage, the reported device structures are often complicated by the use of multiple blocking layers. In this paper, we report a highly simplified three-layered white OLED that achieves a low turn-on voltage of 2.7 V, an external quantum efficiency of 18.9% and power efficiency of 30 lm/W at 1000 cd/cm2. This simple white OLED also shows good color quality with a color rendering index of 75, CIE coordinates (0.42, 0.46), and little color shifting at high luminance. The device consists of a SEL sandwiched between a hole transport layer and an electron transport layer. The SEL comprises a thermally activated delayer fluorescent molecule having dual functions as a blue emitter and as a host for other lower energy emitters. The improved color stability and efficiency in such a simple device structure is explained as due to the elimination of significant energy barriers at various organic-organic interfaces in the traditional devices having multiple blocking layers.

  9. High performance electromagnetic simulation tools

    Science.gov (United States)

    Gedney, Stephen D.; Whites, Keith W.

    1994-10-01

    Army Research Office Grant #DAAH04-93-G-0453 has supported the purchase of 24 additional compute nodes that were installed in the Intel iPsC/860 hypercube at the Univesity Of Kentucky (UK), rendering a 32-node multiprocessor. This facility has allowed the investigators to explore and extend the boundaries of electromagnetic simulation for important areas of defense concerns including microwave monolithic integrated circuit (MMIC) design/analysis and electromagnetic materials research and development. The iPSC/860 has also provided an ideal platform for MMIC circuit simulations. A number of parallel methods based on direct time-domain solutions of Maxwell's equations have been developed on the iPSC/860, including a parallel finite-difference time-domain (FDTD) algorithm, and a parallel planar generalized Yee-algorithm (PGY). The iPSC/860 has also provided an ideal platform on which to develop a 'virtual laboratory' to numerically analyze, scientifically study and develop new types of materials with beneficial electromagnetic properties. These materials simulations are capable of assembling hundreds of microscopic inclusions from which an electromagnetic full-wave solution will be obtained in toto. This powerful simulation tool has enabled research of the full-wave analysis of complex multicomponent MMIC devices and the electromagnetic properties of many types of materials to be performed numerically rather than strictly in the laboratory.

  10. High-Performance Data Converters

    DEFF Research Database (Denmark)

    Steensgaard-Madsen, Jesper

    -resolution internal D/A converters are required. Unit-element mismatch-shaping D/A converters are analyzed, and the concept of mismatch-shaping is generalized to include scaled-element D/A converters. Several types of scaled-element mismatch-shaping D/A converters are proposed. Simulations show that, when implemented...... in a standard CMOS technology, they can be designed to yield 100 dB performance at 10 times oversampling. The proposed scaled-element mismatch-shaping D/A converters are well suited for use as the feedback stage in oversampled delta-sigma quantizers. It is, however, not easy to make full use of their potential......-order difference of the output signal from the loop filter's first integrator stage. This technique avoids the need for accurate matching of analog and digital filters that characterizes the MASH topology, and it preserves the signal-band suppression of quantization errors. Simulations show that quantizers...

  11. High performance soft magnetic materials

    CERN Document Server

    2017-01-01

    This book provides comprehensive coverage of the current state-of-the-art in soft magnetic materials and related applications, with particular focus on amorphous and nanocrystalline magnetic wires and ribbons and sensor applications. Expert chapters cover preparation, processing, tuning of magnetic properties, modeling, and applications. Cost-effective soft magnetic materials are required in a range of industrial sectors, such as magnetic sensors and actuators, microelectronics, cell phones, security, automobiles, medicine, health monitoring, aerospace, informatics, and electrical engineering. This book presents both fundamentals and applications to enable academic and industry researchers to pursue further developments of these key materials. This highly interdisciplinary volume represents essential reading for researchers in materials science, magnetism, electrodynamics, and modeling who are interested in working with soft magnets. Covers magnetic microwires, sensor applications, amorphous and nanocrystalli...

  12. High performance polyethylene nanocomposite fibers

    Directory of Open Access Journals (Sweden)

    A. Dorigato

    2012-12-01

    Full Text Available A high density polyethylene (HDPE matrix was melt compounded with 2 vol% of dimethyldichlorosilane treated fumed silica nanoparticles. Nanocomposite fibers were prepared by melt spinning through a co-rotating twin screw extruder and drawing at 125°C in air. Thermo-mechanical and morphological properties of the resulting fibers were then investigated. The introduction of nanosilica improved the drawability of the fibers, allowing the achievement of higher draw ratios with respect to the neat matrix. The elastic modulus and creep stability of the fibers were remarkably improved upon nanofiller addition, with a retention of the pristine tensile properties at break. Transmission electronic microscope (TEM images evidenced that the original morphology of the silica aggregates was disrupted by the applied drawing.

  13. The performance of an infiltration gallery used as a simple water ...

    African Journals Online (AJOL)

    driniev

    water treatment option for a small rural community ... protection from human contact and a simple iron removal system was installed to remove ... a reliable supply of potable water because of the seasonal drying up .... The pH varied between 6.17 and 7.8 for the pond water with a mean .... The effect of cement on the water.

  14. Simple fabrication of TiO2/C nanocomposite with enhanced electrochemical performance for lithium-ion batteries

    International Nuclear Information System (INIS)

    Bai, Xue; Li, Tao; Qi, Yong-Xin; Gao, Xue-Ping; Yin, Long-Wei; Li, Hui; Zhu, Hui-Ling; Lun, Ning; Bai, Yu-Jun

    2015-01-01

    TiO 2 /C nanocomposites were fabricated by simple hydrolysis of tetrabutyl titanate to yield TiO 2 nanoparticles followed by carbonizing the mixture of glucose and TiO 2 at 600 °C. By merely varying the weight ratio of glucose:TiO 2 , the electrochemical performance of the composites could be optimized significantly. At a ratio of 0.8, the composite exhibits a high reversible capacity of 283.7 mA h g −1 after cycling 100 times at a current density of 100 mA g −1 , as well as the capacities of 245.1, 213.6, 179.9 and 136.6 mA h g −1 at the corresponding densities of 200, 400, 800 and 1600 mA g −1 . After cycling 1000 times at 500 mA g −1 , a capacity of 122.8 mA h g −1 was retained for the composite with a ratio of 0.8, and even a capacity of 149.1 mA h g −1 for the composite with a ratio of 0.7. The enhanced performance is ascribed to the carbon-coated TiO 2 nanoparticles uniformly embedding in the carbon matrix with appropriate carbon content

  15. A simple tool for tubing modification to improve spiral high-speed counter-current chromatography for protein purification.

    Science.gov (United States)

    Ito, Yoichiro; Ma, Xiaofeng; Clary, Robert

    2016-01-01

    A simple tool is introduced which can modify the shape of tubing to enhance the partition efficiency in high-speed countercurrent chromatography. It consists of a pair of interlocking identical gears, each coaxially holding a pressing wheel to intermittently compress plastic tubing in 0 - 10 mm length at every 1 cm interval. The performance of the processed tubing is examined in protein separation with 1.6 mm ID PTFE tubing intermittently pressed in 3 mm and 10 mm width both at 10 mm intervals at various flow rates and revolution speeds. A series of experiments was performed with a polymer phase system composed of polyethylene glycol and dibasic potassium phosphate each at 12.5% (w/w) in deionized water using three protein samples. Overall results clearly demonstrate that the compressed tubing can yield substantially higher peak resolution than the non-processed tubing. The simple tubing modifier is very useful for separation of proteins with high-speed countercurrent chromatography.

  16. High Power Flex-Propellant Arcjet Performance

    Science.gov (United States)

    Litchford, Ron J.

    2011-01-01

    A MW-class electrothermal arcjet based on a water-cooled, wall-stabilized, constricted arc discharge configuration was subjected to extensive performance testing using hydrogen and simulated ammonia propellants with the deliberate aim of advancing technology readiness level for potential space propulsion applications. The breadboard design incorporates alternating conductor/insulator wafers to form a discharge barrel enclosure with a 2.5-cm internal bore diameter and an overall length of approximately 1 meter. Swirling propellant flow is introduced into the barrel, and a DC arc discharge mode is established between a backplate tungsten cathode button and a downstream ringanode/ spin-coil assembly. The arc-heated propellant then enters a short mixing plenum and is accelerated through a converging-diverging graphite nozzle. This innovative design configuration differs substantially from conventional arcjet thrusters, in which the throat functions as constrictor and the expansion nozzle serves as the anode, and permits the attainment of an equilibrium sonic throat (EST) condition. During the test program, applied electrical input power was varied between 0.5-1 MW with hydrogen and simulated ammonia flow rates in the range of 4-12 g/s and 15-35 g/s, respectively. The ranges of investigated specific input energy therefore fell between 50-250 MJ/kg for hydrogen and 10-60 MJ/kg for ammonia. In both cases, observed arc efficiencies were between 40-60 percent as determined via a simple heat balance method based on electrical input power and coolant water calorimeter measurements. These experimental results were found to be in excellent agreement with theoretical chemical equilibrium predictions, thereby validating the EST assumption and enabling the utilization of standard TDK nozzle expansion analyses to reliably infer baseline thruster performance characteristics. Inferred specific impulse performance accounting for recombination kinetics during the expansion process

  17. HIGH-PERFORMANCE COATING MATERIALS

    Energy Technology Data Exchange (ETDEWEB)

    SUGAMA,T.

    2007-01-01

    Corrosion, erosion, oxidation, and fouling by scale deposits impose critical issues in selecting the metal components used at geothermal power plants operating at brine temperatures up to 300 C. Replacing these components is very costly and time consuming. Currently, components made of titanium alloy and stainless steel commonly are employed for dealing with these problems. However, another major consideration in using these metals is not only that they are considerably more expensive than carbon steel, but also the susceptibility of corrosion-preventing passive oxide layers that develop on their outermost surface sites to reactions with brine-induced scales, such as silicate, silica, and calcite. Such reactions lead to the formation of strong interfacial bonds between the scales and oxide layers, causing the accumulation of multiple layers of scales, and the impairment of the plant component's function and efficacy; furthermore, a substantial amount of time is entailed in removing them. This cleaning operation essential for reusing the components is one of the factors causing the increase in the plant's maintenance costs. If inexpensive carbon steel components could be coated and lined with cost-effective high-hydrothermal temperature stable, anti-corrosion, -oxidation, and -fouling materials, this would improve the power plant's economic factors by engendering a considerable reduction in capital investment, and a decrease in the costs of operations and maintenance through optimized maintenance schedules.

  18. A high performance thermoacoustic Stirling-engine

    Energy Technology Data Exchange (ETDEWEB)

    Tijani, M.E.H.; Spoelstra, S. [Energy research Centre of the Netherlands (ECN), PO Box 1, 1755 ZG Petten (Netherlands)

    2011-11-10

    In thermoacoustic systems heat is converted into acoustic energy and vice versa. These systems use inert gases as working medium and have no moving parts which makes the thermoacoustic technology a serious alternative to produce mechanical or electrical power, cooling power, and heating in a sustainable and environmentally friendly way. A thermoacoustic Stirling heat engine is designed and built which achieves a record performance of 49% of the Carnot efficiency. The design and performance of the engine is presented. The engine has no moving parts and is made up of few simple components.

  19. Simple, compact, high brightness source for x-ray lithography and x-ray radiography

    International Nuclear Information System (INIS)

    Hawryluk, A.M.

    1986-01-01

    A simple, compact, high brightness x-ray source has recently been built. This source utilizes a commercially available, cylindrical geometry electron beam evaporator, which has been modified to enhance the thermal cooling to the anode. Cooling is accomplished by using standard, low-conductivity laboratory water, with an inlet pressure of less than 50 psi, and a flow rate of approx.0.3 gal/min. The anode is an inverted cone geometry for efficient cooling. The x-ray source has a measured sub-millimeter spot size (FWHM). The anode has been operated at 1 KW e-beam power (10 KV, 100 ma). Higher operating levels will be investigated. A variety of different x-ray lines can be obtained by the simple interchange of anodes of different materials. Typical anodes are made from easily machined metals, or materials which are vacuum deposited onto a copper anode. Typically, a few microns of material is sufficient to stop 10 KV electrons without significantly decreasing the thermal conductivity through the anode. The small size and high brightness of this source make it useful for step and repeat exposures over several square centimeter areas, especially in a research laboratory environment. For an aluminum anode, the estimated Al-K x-ray flux at 10 cms from the source is 70 μW/cm 2

  20. A Simple Ultra-Wideband Magneto-Electric Dipole Antenna With High Gain

    Science.gov (United States)

    Shuai, Chen-yang; Wang, Guang-ming

    2017-12-01

    A simple ultra-wideband magneto-electric dipole antenna utilizing a differential-fed structure is designed. The antenna mainly comprises three parts, including a novel circular horned reflector, two vertical semicircular shorted patches as a magnetic dipole, and a horizontal U-shaped semicircular electric dipole. A differential feeding structure working as a perfect balun excites the designed antenna. The results of simulation have a good match with the ones of measurement. Results indicate that the designed antenna achieves a wide frequency bandwidth of 107 % which is 3.19 10.61 GHz, when VSWR is below 2. Via introducing the circular horned reflector, the designed antenna attains a steady and high gain of 12±1.5dBi. Moreover, settled broadside direction main beam, high front-to-back ratio, low cross polarization, and the symmetrical and relatively stable radiation patterns in the E-and H-plane are gotten in the impedance bandwidth range. In the practical applications, the proposed antenna that is dc grounded and has a simple structure satisfies the requirement of many outdoor antennas.

  1. Delivering high performance BWR fuel reliably

    International Nuclear Information System (INIS)

    Schardt, J.F.

    1998-01-01

    Utilities are under intense pressure to reduce their production costs in order to compete in the increasingly deregulated marketplace. They need fuel, which can deliver high performance to meet demanding operating strategies. GE's latest BWR fuel design, GE14, provides that high performance capability. GE's product introduction process assures that this performance will be delivered reliably, with little risk to the utility. (author)

  2. Dramatic improvement of membrane performance for microalgae harvesting with a simple bubble-generator plate.

    Science.gov (United States)

    Hwang, Taewoon; Oh, You-Kwan; Kim, Bohwa; Han, Jong-In

    2015-06-01

    To overcome fouling issue in membrane-based algae harvesting and thus make an otherwise promising harvesting option more competitive, a bubble-generator plate was developed. According to computational fluid dynamics analysis, the plate generated substantial hydrodynamic power in terms of high pressure, velocity, and shear stress. When installed in a membrane filtration system with membranes of different surface and structural characteristics (one prepared by the phase inversion method, and a commercial one) the bubble-generator was indeed effective in reducing fouling. Without the plate, the much cheaper homemade membrane had the similar performance as the commercial one. Use of the bubble-generator considerably improved the performance of both membranes, and revealed a valuable synergy with the asymmetrical structure of the homemade membrane. This result clearly showed that the ever-problematic fouling could be mitigated in a rather easy manner, and in so doing, that membrane technology could indeed become a practical option for algae harvesting. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. A simple compact UHV and high magnetic field compatible inertial nanopositioner

    Science.gov (United States)

    Pang, Zongqiang; Li, Xiang; Xu, Lei; Rong, Zhou; Liu, Ruilan

    2015-01-01

    We present a novel simple piezoelectric nanopositioner which just has one piezoelectric scanner tube (PST) and one driving signal, using two short quartz rods and one BeCu spring which form a triangle to press the central shaft and can promise the nanopositioner's rigidity. Applying two pulse inverted voltage signals on the PST's outer and inner electrodes, respectively, according to the principle of piezoelectricity, the PST will elongate or contract suddenly while the central shaft will keep stationary for its inertance, so the central shaft will be sliding a distance relative to quartz rods and spring, and then withdraw the pulse voltages slowly, the central shaft will move upward or downward one step. The heavier of the central shaft, the better moving stability, so the nanopositioner has high output force. Due to its compactness and mechanical stability, it can be easily implanted into some extreme conditions, such as ultrahigh vacuum, ultralow temperature, and high magnetic field.

  4. Communication: High pressure specific heat spectroscopy reveals simple relaxation behavior of glass forming molecular liquid

    DEFF Research Database (Denmark)

    Roed, Lisa Anita; Niss, Kristine; Jakobsen, Bo

    2015-01-01

    The frequency dependent specific heat has been measured under pressure for the molecular glass forming liquid 5-polyphenyl-4-ether in the viscous regime close to the glass transition. The temperature and pressure dependences of the characteristic time scale associated with the specific heat...... is compared to the equivalent time scale from dielectric spectroscopy performed under identical conditions. It is shown that the ratio between the two time scales is independent of both temperature and pressure. This observation is non-trivial and demonstrates the existence of specially simple molecular...... liquids in which different physical relaxation processes are both as function of temperature and pressure/density governed by the same underlying “inner clock.” Furthermore, the results are discussed in terms of the recent conjecture that van der Waals liquids, like the measuredliquid, comply...

  5. High performance carbon nanocomposites for ultracapacitors

    Science.gov (United States)

    Lu, Wen

    2012-10-02

    The present invention relates to composite electrodes for electrochemical devices, particularly to carbon nanotube composite electrodes for high performance electrochemical devices, such as ultracapacitors.

  6. Cu-Au alloy nanostructures coated with aptamers: a simple, stable and highly effective platform for in vivo cancer theranostics

    Science.gov (United States)

    Ye, Xiaosheng; Shi, Hui; He, Xiaoxiao; Yu, Yanru; He, Dinggeng; Tang, Jinlu; Lei, Yanli; Wang, Kemin

    2016-01-01

    As a star material in cancer theranostics, photoresponsive gold (Au) nanostructures may still have drawbacks, such as low thermal conductivity, irradiation-induced melting effect and high cost. To solve the problem, copper (Cu) with a much higher thermal conductivity and lower cost was introduced to generate a novel Cu-Au alloy nanostructure produced by a simple, gentle and one-pot synthetic method. Having the good qualities of both Cu and Au, the irregularly-shaped Cu-Au alloy nanostructures showed several advantages over traditional Au nanorods, including a broad and intense near-infrared (NIR) absorption band from 400 to 1100 nm, an excellent heating performance under laser irradiation at different wavelengths and even a notable photostability against melting. Then, via a simple conjugation of fluorophore-labeled aptamers on the Cu-Au alloy nanostructures, active targeting and signal output were simultaneously introduced, thus constructing a theranostic platform based on fluorophore-labeled, aptamer-coated Cu-Au alloy nanostructures. By using human leukemia CCRF-CEM cancer and Cy5-labeled aptamer Sgc8c (Cy5-Sgc8c) as the model, a selective fluorescence imaging and NIR photothermal therapy was successfully realized for both in vitro cancer cells and in vivo tumor tissues. It was revealed that Cy5-Sgc8c-coated Cu-Au alloy nanostructures were not only capable of robust target recognition and stable signal output for molecular imaging in complex biological systems, but also killed target cancer cells in mice with only five minutes of 980 nm irradiation. The platform was found to be simple, stable, biocompatible and highly effective, and shows great potential as a versatile tool for cancer theranostics.As a star material in cancer theranostics, photoresponsive gold (Au) nanostructures may still have drawbacks, such as low thermal conductivity, irradiation-induced melting effect and high cost. To solve the problem, copper (Cu) with a much higher thermal conductivity

  7. Non-Doped Sky-Blue OLEDs Based on Simple Structured AIE Emitters with High Efficiencies at Low Driven Voltages.

    Science.gov (United States)

    Islam, Amjad; Zhang, Dongdong; Peng, Ruixiang; Yang, Rongjuan; Hong, Ling; Song, Wei; Wei, Qiang; Duan, Lian; Ge, Ziyi

    2017-09-05

    Blue organic light-emitting diodes (OLEDs) are necessary for flat-panel display technologies and lighting applications. To make more energy-saving, low-cost and long-lasting OLEDs, efficient materials as well as simple structured devices are in high demand. However, a very limited number of blue OLEDs achieving high stability and color purity have been reported. Herein, three new sky-blue emitters, 1,4,5-triphenyl-2-(4-(1,2,2-triphenylvinyl)phenyl)-1H-imidazole (TPEI), 1-(4-methoxyphenyl)-4,5-diphenyl-2-(4-(1,2,2-triphenylvinyl)phenyl)-1H-imidazole (TPEMeOPhI) and 1-phenyl-2,4,5-tris(4-(1,2,2-triphenylvinyl)phenyl)-1H-imidazole (3TPEI), with a combination of imidazole and tetraphenylethene groups, have been developed. High photoluminescence quantum yields are obtained for these materials. All derivatives have demonstrated aggregation-induced emission (AIE) behavior, excellent thermal stability with high decomposition and glass transition temperatures. Non-doped sky-blue OLEDs with simple structure have been fabricated employing these materials as emitters and realized high efficiencies of 2.41 % (4.92 cd A -1 , 2.70 lm W -1 ), 2.16 (4.33 cd A -1 , 2.59 lm W -1 ) and 3.13 % (6.97 cd A -1 , 4.74 lm W -1 ) for TPEI, TPEMeOPhI and 3TPEI, with small efficiency roll-off. These are among excellent results for molecules constructed from the combination of imidazole and TPE reported so far. The high performance of a 3TPEI-based device shows the promising potential of the combination of imidazole and AIEgen for synthesizing efficient electroluminescent materials for OLED devices. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Strategies and Experiences Using High Performance Fortran

    National Research Council Canada - National Science Library

    Shires, Dale

    2001-01-01

    .... High performance Fortran (HPF) is a relative new addition to the Fortran dialect It is an attempt to provide an efficient high-level Fortran parallel programming language for the latest generation of been debatable...

  9. High Performance Grinding and Advanced Cutting Tools

    CERN Document Server

    Jackson, Mark J

    2013-01-01

    High Performance Grinding and Advanced Cutting Tools discusses the fundamentals and advances in high performance grinding processes, and provides a complete overview of newly-developing areas in the field. Topics covered are grinding tool formulation and structure, grinding wheel design and conditioning and applications using high performance grinding wheels. Also included are heat treatment strategies for grinding tools, using grinding tools for high speed applications, laser-based and diamond dressing techniques, high-efficiency deep grinding, VIPER grinding, and new grinding wheels.

  10. Strategy Guideline: High Performance Residential Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Holton, J.

    2012-02-01

    The Strategy Guideline: High Performance Residential Lighting has been developed to provide a tool for the understanding and application of high performance lighting in the home. The high performance lighting strategies featured in this guide are drawn from recent advances in commercial lighting for application to typical spaces found in residential buildings. This guide offers strategies to greatly reduce lighting energy use through the application of high quality fluorescent and light emitting diode (LED) technologies. It is important to note that these strategies not only save energy in the home but also serve to satisfy the homeowner's expectations for high quality lighting.

  11. Carbon nanomaterials for high-performance supercapacitors

    OpenAIRE

    Tao Chen; Liming Dai

    2013-01-01

    Owing to their high energy density and power density, supercapacitors exhibit great potential as high-performance energy sources for advanced technologies. Recently, carbon nanomaterials (especially, carbon nanotubes and graphene) have been widely investigated as effective electrodes in supercapacitors due to their high specific surface area, excellent electrical and mechanical properties. This article summarizes the recent progresses on the development of high-performance supercapacitors bas...

  12. A simple and highly efficient Agrobacterium-mediated transformation protocol for Setaria viridis

    Directory of Open Access Journals (Sweden)

    Polyana Kelly Martins

    2015-06-01

    Full Text Available The production and use of sugarcane in Brazil is very important for bioenergy production and is recognized as one of the most efficient in the world. In our laboratory, Setaria viridis is being tested as a model plant for sugarcane. S. viridis has biological attributes (rapid life cycle, small genome, diploid, short stature and simple growth requirements that make it suitable for use as a model system. We report a highly efficient protocol for Agrobacterium-mediated genetic transformation of S. viridis. The optimization of several steps in tissue culture allowed the rapid regeneration of plants and increased the rate of transformation up to 29%. This protocol could become a powerful tool for functional genomics in sugarcane.

  13. A simple and rapid method for high-resolution visualization of single-ion tracks

    Directory of Open Access Journals (Sweden)

    Masaaki Omichi

    2014-11-01

    Full Text Available Prompt determination of spatial points of single-ion tracks plays a key role in high-energy particle induced-cancer therapy and gene/plant mutations. In this study, a simple method for the high-resolution visualization of single-ion tracks without etching was developed through the use of polyacrylic acid (PAA-N, N’-methylene bisacrylamide (MBAAm blend films. One of the steps of the proposed method includes exposure of the irradiated films to water vapor for several minutes. Water vapor was found to promote the cross-linking reaction of PAA and MBAAm to form a bulky cross-linked structure; the ion-track scars were detectable at a nanometer scale by atomic force microscopy. This study demonstrated that each scar is easily distinguishable, and the amount of generated radicals of the ion tracks can be estimated by measuring the height of the scars, even in highly dense ion tracks. This method is suitable for the visualization of the penumbra region in a single-ion track with a high spatial resolution of 50 nm, which is sufficiently small to confirm that a single ion hits a cell nucleus with a size ranging between 5 and 20 μm.

  14. A simple and rapid method for high-resolution visualization of single-ion tracks

    Energy Technology Data Exchange (ETDEWEB)

    Omichi, Masaaki [Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Osaka 565-0871 (Japan); Center for Collaborative Research, Anan National College of Technology, Anan, Tokushima 774-0017 (Japan); Choi, Wookjin; Sakamaki, Daisuke; Seki, Shu, E-mail: seki@chem.eng.osaka-u.ac.jp [Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Osaka 565-0871 (Japan); Tsukuda, Satoshi [Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi 980-8577 (Japan); Sugimoto, Masaki [Japan Atomic Energy Agency, Takasaki Advanced Radiation Research Institute, Gunma, Gunma 370-1292 (Japan)

    2014-11-15

    Prompt determination of spatial points of single-ion tracks plays a key role in high-energy particle induced-cancer therapy and gene/plant mutations. In this study, a simple method for the high-resolution visualization of single-ion tracks without etching was developed through the use of polyacrylic acid (PAA)-N, N’-methylene bisacrylamide (MBAAm) blend films. One of the steps of the proposed method includes exposure of the irradiated films to water vapor for several minutes. Water vapor was found to promote the cross-linking reaction of PAA and MBAAm to form a bulky cross-linked structure; the ion-track scars were detectable at a nanometer scale by atomic force microscopy. This study demonstrated that each scar is easily distinguishable, and the amount of generated radicals of the ion tracks can be estimated by measuring the height of the scars, even in highly dense ion tracks. This method is suitable for the visualization of the penumbra region in a single-ion track with a high spatial resolution of 50 nm, which is sufficiently small to confirm that a single ion hits a cell nucleus with a size ranging between 5 and 20 μm.

  15. Theoretical comparison of performance using transfer functions for reactivity meters based on inverse kinetic method and simple feedback method

    International Nuclear Information System (INIS)

    Shimazu, Yoichiro; Tashiro, Shoichi; Tojo, Masayuki

    2017-01-01

    The performance of two digital reactivity meters, one based on the conventional inverse kinetic method and the other one based on simple feedback theory, are compared analytically using their respective transfer functions. The latter one is proposed by one of the authors. It has been shown that the performance of the two reactivity meters become almost identical when proper system parameters are selected for each reactivity meter. A new correlation between the system parameters of the two reactivity meters is found. With this correlation, filter designers can easily determine the system parameters for the respective reactivity meters to obtain identical performance. (author)

  16. Performance Considerations for the SIMPL Single Photon, Polarimetric, Two-Color Laser Altimeter as Applied to Measurements of Forest Canopy Structure and Composition

    Science.gov (United States)

    Dabney, Philip W.; Harding, David J.; Valett, Susan R.; Vasilyev, Aleksey A.; Yu, Anthony W.

    2012-01-01

    The Slope Imaging Multi-polarization Photon-counting Lidar (SIMPL) is a multi-beam, micropulse airborne laser altimeter that acquires active and passive polarimetric optical remote sensing measurements at visible and near-infrared wavelengths. SIMPL was developed to demonstrate advanced measurement approaches of potential benefit for improved, more efficient spaceflight laser altimeter missions. SIMPL data have been acquired for wide diversity of forest types in the summers of 2010 and 2011 in order to assess the potential of its novel capabilities for characterization of vegetation structure and composition. On each of its four beams SIMPL provides highly-resolved measurements of forest canopy structure by detecting single-photons with 15 cm ranging precision using a narrow-beam system operating at a laser repetition rate of 11 kHz. Associated with that ranging data SIMPL provides eight amplitude parameters per beam unlike the single amplitude provided by typical laser altimeters. Those eight parameters are received energy that is parallel and perpendicular to that of the plane-polarized transmit pulse at 532 nm (green) and 1064 nm (near IR), for both the active laser backscatter retro-reflectance and the passive solar bi-directional reflectance. This poster presentation will cover the instrument architecture and highlight the performance of the SIMPL instrument with examples taken from measurements for several sites with distinct canopy structures and compositions. Specific performance areas such as probability of detection, after pulsing, and dead time, will be highlighted and addressed, along with examples of their impact on the measurements and how they limit the ability to accurately model and recover the canopy properties. To assess the sensitivity of SIMPL's measurements to canopy properties an instrument model has been implemented in the FLIGHT radiative transfer code, based on Monte Carlo simulation of photon transport. SIMPL data collected in 2010 over

  17. Enabling People with Developmental Disabilities to Actively Follow Simple Instructions and Perform Designated Occupational Activities According to Simple Instructions with Battery-Free Wireless Mice by Controlling Environmental Stimulation

    Science.gov (United States)

    Shih, Ching-Hsiang; Chang, Man-Ling

    2012-01-01

    This study extended Battery-free wireless mouse functionality to assess whether two people with developmental disabilities would be able to actively perform designated simple occupational activities according to simple instructions by controlling their favorite environmental stimulation using Battery-free wireless mice with a newly developed…

  18. Team Development for High Performance Management.

    Science.gov (United States)

    Schermerhorn, John R., Jr.

    1986-01-01

    The author examines a team development approach to management that creates shared commitments to performance improvement by focusing the attention of managers on individual workers and their task accomplishments. It uses the "high-performance equation" to help managers confront shared beliefs and concerns about performance and develop realistic…

  19. A Simple Setup to Perform 3D Locomotion Tracking in Zebrafish by Using a Single Camera

    Directory of Open Access Journals (Sweden)

    Gilbert Audira

    2018-02-01

    Full Text Available Generally, the measurement of three-dimensional (3D swimming behavior in zebrafish relies on commercial software or requires sophisticated scripts, and depends on more than two cameras to capture the video. Here, we establish a simple and economic apparatus to detect 3D locomotion in zebrafish, which involves a single camera capture system that records zebrafish movement in a specially designed water tank with a mirror tilted at 45 degrees. The recorded videos are analyzed using idTracker, while spatial positions are calibrated by ImageJ software and 3D trajectories are plotted by Origin 9.1 software. This easy setting allowed scientists to track 3D swimming behavior of multiple zebrafish with low cost and precise spatial position, showing great potential for fish behavioral research in the future.

  20. Delivering high performance BWR fuel reliably

    Energy Technology Data Exchange (ETDEWEB)

    Schardt, J.F. [GE Nuclear Energy, Wilmington, NC (United States)

    1998-07-01

    Utilities are under intense pressure to reduce their production costs in order to compete in the increasingly deregulated marketplace. They need fuel, which can deliver high performance to meet demanding operating strategies. GE's latest BWR fuel design, GE14, provides that high performance capability. GE's product introduction process assures that this performance will be delivered reliably, with little risk to the utility. (author)

  1. HPTA: High-Performance Text Analytics

    OpenAIRE

    Vandierendonck, Hans; Murphy, Karen; Arif, Mahwish; Nikolopoulos, Dimitrios S.

    2017-01-01

    One of the main targets of data analytics is unstructured data, which primarily involves textual data. High-performance processing of textual data is non-trivial. We present the HPTA library for high-performance text analytics. The library helps programmers to map textual data to a dense numeric representation, which can be handled more efficiently. HPTA encapsulates three performance optimizations: (i) efficient memory management for textual data, (ii) parallel computation on associative dat...

  2. Short Communication: A Simple Method for Performing Worm-Egg Counts on Sodium Acetate Formaldehyde-Preserved Samples

    Directory of Open Access Journals (Sweden)

    Wayne Melrose

    2012-01-01

    Full Text Available The Kato Katz method is the most common way of performing worm-egg counts on human faecal samples, but it must be done in the field using freshly collected samples. This makes it difficult to use in remote, poorly accessible situations. This paper describes a simple method for egg counts on preserved samples collected in the field and sent to a central location for further processing.

  3. Graphene–sponges as high-performance low-cost anodes for microbial fuel cells

    KAUST Repository

    Xie, Xing; Yu, Guihua; Liu, Nian; Bao, Zhenan; Criddle, Craig S.; Cui, Yi

    2012-01-01

    A high-performance microbial fuel cell (MFC) anode was constructed from inexpensive materials. Key components were a graphene-sponge (G-S) composite and a stainless-steel (SS) current collector. Anode fabrication is simple, scalable

  4. Simplified High-Performance Roll Out Composite Magnetometer Boom, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — In response to NASA's need for compact, low-cost deployable magnetometer booms for CubeSats, Roccor proposes to develop a Simple High-performance Roll-Out Composite...

  5. Multi-actuation and PI control: A simple recipe for high-speed and large-range atomic force microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Soltani Bozchalooi, I., E-mail: isoltani@mit.edu; Youcef-Toumi, K.

    2014-11-15

    High speed atomic force microscopy enables observation of dynamic nano-scale processes. However, maintaining a minimal interaction force between the sample and the probe is challenging at high speed specially when using conventional piezo-tubes. While rigid AFM scanners are operational at high speeds with the drawback of reduced tracking range, multi-actuation schemes have shown potential for high-speed and large-range imaging. Here we present a method to seamlessly incorporate additional actuators into conventional AFMs. The equivalent behavior of the resulting multi-actuated setup resembles that of a single high-speed and large-range actuator with maximally flat frequency response. To achieve this, the dynamics of the individual actuators and their couplings are treated through a simple control scheme. Upon the implementation of the proposed technique, commonly used PI controllers are able to meet the requirements of high-speed imaging. This forms an ideal platform for retroactive enhancement of existing AFMs with minimal cost and without compromise on the tracking range. A conventional AFM with tube scanner is retroactively enhanced through the proposed method and shows an order of magnitude improvement in closed loop bandwidth performance while maintaining large range. The effectiveness of the method is demonstrated on various types of samples imaged in contact and tapping modes, in air and in liquid. - Highlights: • We present a novel method to incorporate extra actuators into conventional AFMs. • A maximally flat frequency response is achieved for the out of plane piezo-motion. • Commonly used PI or PID control is enabled to handle high speed AFM imaging. • An order of magnitude improvement in closed loop bandwidth performance is obtained. • High speed imaging is achieved on a large range piezo-tube.

  6. Multi-actuation and PI control: A simple recipe for high-speed and large-range atomic force microscopy

    International Nuclear Information System (INIS)

    Soltani Bozchalooi, I.; Youcef-Toumi, K.

    2014-01-01

    High speed atomic force microscopy enables observation of dynamic nano-scale processes. However, maintaining a minimal interaction force between the sample and the probe is challenging at high speed specially when using conventional piezo-tubes. While rigid AFM scanners are operational at high speeds with the drawback of reduced tracking range, multi-actuation schemes have shown potential for high-speed and large-range imaging. Here we present a method to seamlessly incorporate additional actuators into conventional AFMs. The equivalent behavior of the resulting multi-actuated setup resembles that of a single high-speed and large-range actuator with maximally flat frequency response. To achieve this, the dynamics of the individual actuators and their couplings are treated through a simple control scheme. Upon the implementation of the proposed technique, commonly used PI controllers are able to meet the requirements of high-speed imaging. This forms an ideal platform for retroactive enhancement of existing AFMs with minimal cost and without compromise on the tracking range. A conventional AFM with tube scanner is retroactively enhanced through the proposed method and shows an order of magnitude improvement in closed loop bandwidth performance while maintaining large range. The effectiveness of the method is demonstrated on various types of samples imaged in contact and tapping modes, in air and in liquid. - Highlights: • We present a novel method to incorporate extra actuators into conventional AFMs. • A maximally flat frequency response is achieved for the out of plane piezo-motion. • Commonly used PI or PID control is enabled to handle high speed AFM imaging. • An order of magnitude improvement in closed loop bandwidth performance is obtained. • High speed imaging is achieved on a large range piezo-tube

  7. Fast learning of simple perceptual discriminations reduces brain activation in working memory and in high-level auditory regions.

    Science.gov (United States)

    Daikhin, Luba; Ahissar, Merav

    2015-07-01

    Introducing simple stimulus regularities facilitates learning of both simple and complex tasks. This facilitation may reflect an implicit change in the strategies used to solve the task when successful predictions regarding incoming stimuli can be formed. We studied the modifications in brain activity associated with fast perceptual learning based on regularity detection. We administered a two-tone frequency discrimination task and measured brain activation (fMRI) under two conditions: with and without a repeated reference tone. Although participants could not explicitly tell the difference between these two conditions, the introduced regularity affected both performance and the pattern of brain activation. The "No-Reference" condition induced a larger activation in frontoparietal areas known to be part of the working memory network. However, only the condition with a reference showed fast learning, which was accompanied by a reduction of activity in two regions: the left intraparietal area, involved in stimulus retention, and the posterior superior-temporal area, involved in representing auditory regularities. We propose that this joint reduction reflects a reduction in the need for online storage of the compared tones. We further suggest that this change reflects an implicit strategic shift "backwards" from reliance mainly on working memory networks in the "No-Reference" condition to increased reliance on detected regularities stored in high-level auditory networks.

  8. Strategy Guideline. Partnering for High Performance Homes

    Energy Technology Data Exchange (ETDEWEB)

    Prahl, Duncan [IBACOS, Inc., Pittsburgh, PA (United States)

    2013-01-01

    High performance houses require a high degree of coordination and have significant interdependencies between various systems in order to perform properly, meet customer expectations, and minimize risks for the builder. Responsibility for the key performance attributes is shared across the project team and can be well coordinated through advanced partnering strategies. For high performance homes, traditional partnerships need to be matured to the next level and be expanded to all members of the project team including trades, suppliers, manufacturers, HERS raters, designers, architects, and building officials as appropriate. This guide is intended for use by all parties associated in the design and construction of high performance homes. It serves as a starting point and features initial tools and resources for teams to collaborate to continually improve the energy efficiency and durability of new houses.

  9. A Simple Demonstration of the High-Temperature Electrical Conductivity of Glass

    Science.gov (United States)

    Chiaverina, Chris

    2014-01-01

    We usually think of glass as a good electrical insulator; this, however, is not always the case. There are several ways to show that glass becomes conducting at high temperatures, but the following approach, devised by Brown University demonstration manager Gerald Zani, may be one of the simplest to perform.

  10. High Operating Voltage Supercapacitor Using PPy/AC Composite Electrode Based on Simple Dipping Method

    Directory of Open Access Journals (Sweden)

    Kyoungho Kim

    2015-01-01

    Full Text Available As various wearable devices are emerging, self-generated power sources, such as piezoelectric generators, triboelectric generators, and thermoelectric generators, are of interest. To adapt self-generated power sources for application devices, a supercapacitor is necessary because of the short generation times (1–10 ms and low generated power (1–100 μW of self-generated power sources. However, to date, supercapacitors are too large to be adapted for wearable devices. There have been many efforts to reduce the size of supercapacitors by using polypyrrole (PPy for high energy supercapacitor electrodes. However, these supercapacitors have several disadvantages, such as a low operating voltage due to the use of an aqueous electrolyte, and complex manufacturing methods, such as the hydrogel and aerosol methods. In particular, the low operating voltage (~1.0 V is a significant issue because most electronic components operate above 3.0 V. In this study, we successfully demonstrated the high operating voltage (3.0 V of a supercapacitor using a PPy/activated carbon (AC composite electrode based on the chemical polymerization of the PPy by simple dipping. In addition, a twofold enhancement of its energy density was achieved compared with conventional supercapacitors using AC electrodes.

  11. A simple model for prediction postpartum PTSD in high-risk pregnancies.

    Science.gov (United States)

    Shlomi Polachek, Inbal; Dulitzky, Mordechai; Margolis-Dorfman, Lilia; Simchen, Michal J

    2016-06-01

    This study aimed to examine the prevalence and possible antepartum risk factors of complete and partial post-traumatic stress disorder (PTSD) among women with complicated pregnancies and to define a predictive model for postpartum PTSD in this population. Women attending the high-risk pregnancy outpatient clinics at Sheba Medical Center completed the Edinburgh Postnatal Depression Scale (EPDS) and a questionnaire regarding demographic variables, history of psychological and psychiatric treatment, previous trauma, previous childbirth, current pregnancy medical and emotional complications, fears from childbirth, and expected pain. One month after delivery, women were requested to repeat the EPDS and complete the Post-traumatic Stress Diagnostic Scale (PDS) via telephone interview. The prevalence rates of postpartum PTSD (9.9 %) and partial PTSD (11.9 %) were relatively high. PTSD and partial PTSD were associated with sadness or anxiety during past pregnancy or childbirth, previous very difficult birth experiences, preference for cesarean section in future childbirth, emotional crises during pregnancy, increased fear of childbirth, higher expected intensity of pain, and depression during pregnancy. We created a prediction model for postpartum PTSD which shows a linear growth in the probability for developing postpartum PTSD when summing these seven antenatal risk factors. Postpartum PTSD is extremely prevalent after complicated pregnancies. A simple questionnaire may aid in identifying at-risk women before childbirth. This presents a potential for preventing or minimizing postpartum PTSD in this population.

  12. A Simple Test Tube-Based ELISA Experiment for the High-School Classroom*

    Science.gov (United States)

    Brokaw, Ann; Cobb, Brian A.

    2010-01-01

    Immunology is gaining prominence both in the media as well as on the Advanced Placement (AP) exam in Biology. One of the challenges of teaching modern biological topics such as immunology and biochemistry in the high-school setting is the increased reliance on expensive technology in the research world. To begin to bridge this widening gap, we devised an experiment using a novel macroscale enzyme-linked immunosorbent assay that is suitable for AP-level high-school biology classrooms as well as entry-level collegiate laboratories. This novel method does not require a plate reader for data analysis, but instead relies on more common and inexpensive equipment such as a clinical test tube centrifuge and a simple test tube spectrophotometer. The experimental plan focuses on students measuring antibody concentrations in “unknown” samples and includes the collection and analysis of a standard curve using reagents prepared by the instructor. Students will be introduced to enzyme action, quantitative laboratory technique, antibodies, and the immune system, with the overall goal being to explore and highlight the inherent connections within the fields of biochemistry and immunology. PMID:20689684

  13. Boosting the Performance of the Nickel Anode in the Oxygen Evolution Reaction by Simple Electrochemical Activation

    KAUST Repository

    Shinagawa, Tatsuya

    2017-03-27

    The development of cost-effective and active water-splitting electrocatalysts that work at mild pH is an essential step towards the realization of sustainable energy and material circulation in our society. Its success requires a drastic improvement in the kinetics of the anodic half-reaction of the oxygen evolution reaction (OER), which determines the overall system efficiency to a large extent. A simple electrochemical protocol has been developed to activate Ni electrodes, by which a stable NiOOH phase was formed, which could weakly bind to alkali-metal cations. The electrochemically activated (ECA) Ni electrode reached a current of 10 mA at <1.40 V vs. the reversible hydrogen electrode (RHE) at practical operation temperatures (>75 °C) and a mild pH of ca. 10 with excellent stability (>24 h), greatly surpassing that of the state-of-the-art NiFeOx electrodes under analogous conditions. Water electrolysis was demonstrated with ECA-Ni and NiMo, which required an iR-free overall voltage of only 1.44 V to reach 10 mA cmgeo(-2) .

  14. Boosting the performance of the nickel anode in the oxygen evolution reaction by simple electrochemical activation

    Energy Technology Data Exchange (ETDEWEB)

    Shinagawa, Tatsuya; Ng, Marcus Tze-Kiat; Takanabe, Kazuhiro [King Abdullah Univ. of Science and Technology (KAUST), KAUST Catalysis Center (KCC) and Physical Sciences and Engineering Div. PSE, Thuwal (Saudi Arabia)

    2017-04-24

    The development of cost-effective and active water-splitting electrocatalysts that work at mild pH is an essential step towards the realization of sustainable energy and material circulation in our society. Its success requires a drastic improvement in the kinetics of the anodic half-reaction of the oxygen evolution reaction (OER), which determines the overall system efficiency to a large extent. A simple electrochemical protocol has been developed to activate Ni electrodes, by which a stable NiOOH phase was formed, which could weakly bind to alkali-metal cations. The electrochemically activated (ECA) Ni electrode reached a current of 10 mA at <1.40 V vs. the reversible hydrogen electrode (RHE) at practical operation temperatures (>75 C) and a mild pH of ca. 10 with excellent stability (>24 h), greatly surpassing that of the state-of-the-art NiFeO{sub x} electrodes under analogous conditions. Water electrolysis was demonstrated with ECA-Ni and NiMo, which required an iR-free overall voltage of only 1.44 V to reach 10 mA cm{sub geo}{sup -2}. (copyright 2017 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

  15. High-performance ceramics. Fabrication, structure, properties

    International Nuclear Information System (INIS)

    Petzow, G.; Tobolski, J.; Telle, R.

    1996-01-01

    The program ''Ceramic High-performance Materials'' pursued the objective to understand the chaining of cause and effect in the development of high-performance ceramics. This chain of problems begins with the chemical reactions for the production of powders, comprises the characterization, processing, shaping and compacting of powders, structural optimization, heat treatment, production and finishing, and leads to issues of materials testing and of a design appropriate to the material. The program ''Ceramic High-performance Materials'' has resulted in contributions to the understanding of fundamental interrelationships in terms of materials science, which are summarized in the present volume - broken down into eight special aspects. (orig./RHM)

  16. High Burnup Fuel Performance and Safety Research

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Je Keun; Lee, Chan Bok; Kim, Dae Ho (and others)

    2007-03-15

    The worldwide trend of nuclear fuel development is to develop a high burnup and high performance nuclear fuel with high economies and safety. Because the fuel performance evaluation code, INFRA, has a patent, and the superiority for prediction of fuel performance was proven through the IAEA CRP FUMEX-II program, the INFRA code can be utilized with commercial purpose in the industry. The INFRA code was provided and utilized usefully in the universities and relevant institutes domesticallly and it has been used as a reference code in the industry for the development of the intrinsic fuel rod design code.

  17. ADVANCED HIGH PERFORMANCE SOLID WALL BLANKET CONCEPTS

    International Nuclear Information System (INIS)

    WONG, CPC; MALANG, S; NISHIO, S; RAFFRAY, R; SAGARA, S

    2002-01-01

    OAK A271 ADVANCED HIGH PERFORMANCE SOLID WALL BLANKET CONCEPTS. First wall and blanket (FW/blanket) design is a crucial element in the performance and acceptance of a fusion power plant. High temperature structural and breeding materials are needed for high thermal performance. A suitable combination of structural design with the selected materials is necessary for D-T fuel sufficiency. Whenever possible, low afterheat, low chemical reactivity and low activation materials are desired to achieve passive safety and minimize the amount of high-level waste. Of course the selected fusion FW/blanket design will have to match the operational scenarios of high performance plasma. The key characteristics of eight advanced high performance FW/blanket concepts are presented in this paper. Design configurations, performance characteristics, unique advantages and issues are summarized. All reviewed designs can satisfy most of the necessary design goals. For further development, in concert with the advancement in plasma control and scrape off layer physics, additional emphasis will be needed in the areas of first wall coating material selection, design of plasma stabilization coils, consideration of reactor startup and transient events. To validate the projected performance of the advanced FW/blanket concepts the critical element is the need for 14 MeV neutron irradiation facilities for the generation of necessary engineering design data and the prediction of FW/blanket components lifetime and availability

  18. High Contrast Coherent Population Trapping Resonances in Cs Vapour Cells with a Simple-Architecture Laser System

    International Nuclear Information System (INIS)

    Liu, Xiaochi

    2013-01-01

    This thesis reports the development of a simple-architecture laser system resonant at 895 nm used for the detection of high-contrast coherent population trapping (CPT) resonances in Cs vapor cells. The laser system combines a distributed feedback-diode (DFB) laser, a pigtailed Mach-Zehnder intensity electro-optic modulator (EOM) driven at 4.596 GHz for the generation of optical sidebands frequency-split by 9.192 GHz and a Michelson delay-line system to produce a bi-chromatic optical field that alternates between right and left circular polarization. This polarization pumping scheme, first proposed by Happer's group in Princeton on K atoms, allows to optically pump a maximum number of Cs atoms into the 0-0 magnetic field insensitive clock transition. Advanced noise reduction techniques were implemented in order to stabilize the laser power, the optical carrier suppression at the output of the EOM and the DFB laser frequency. Using this system, we demonstrated the detection of CPT resonances with a contrast of 80% in cm-scale Cs vapor cells. This contrast was measured to be increased until a saturation effect with the laser power at the expense of the CPT line broadening. To circumvent this issue, we proposed with a simple setup Ramsey spectroscopy of CPT resonances in vapor cells to combine high-contrast and narrow line width of the CPT resonances. In this setup, the EOM is used both for optical sidebands generation and light switch to produce Ramsey interaction. Ramsey fringes of 166 Hz line width with a contrast better than 30% were detected with this setup. This laser system will be in a near future devoted to be used for the development of a high-performance CPT-based atomic clock. (author)

  19. Performance Analysis of Simple Channel Feedback Schemes for a Practical OFDMA System

    DEFF Research Database (Denmark)

    Pedersen, Klaus, I.; Kolding, Troels; Kovacs, Istvan

    2009-01-01

    In this paper, we evaluate the tradeoff between the amount of uplink channel feedback information and the orthogonal frequency-division multiple access (OFDMA) downlink performance with opportunistic frequency-domain packet scheduling. Three candidate channel feedback schemes are investigated......, including practical aspects, such as the effects of terminal measurement errors, bandwidth measurement granularity, quantization, and uplink signaling delays. The performance is evaluated by means of system-level simulations with detailed modeling of various radio resource-management algorithms, etc. Our...... results show that the optimal tradeoff between the channel feedback and the downlink OFDMA system performance depends on the radio channel frequency coherence bandwidth. We conclude that the so-called average best-M scheme is the most attractive channel feedback solution, where only the average channel...

  20. Performance of the Tariff Method: validation of a simple additive algorithm for analysis of verbal autopsies

    Directory of Open Access Journals (Sweden)

    Murray Christopher JL

    2011-08-01

    Full Text Available Abstract Background Verbal autopsies provide valuable information for studying mortality patterns in populations that lack reliable vital registration data. Methods for transforming verbal autopsy results into meaningful information for health workers and policymakers, however, are often costly or complicated to use. We present a simple additive algorithm, the Tariff Method (termed Tariff, which can be used for assigning individual cause of death and for determining cause-specific mortality fractions (CSMFs from verbal autopsy data. Methods Tariff calculates a score, or "tariff," for each cause, for each sign/symptom, across a pool of validated verbal autopsy data. The tariffs are summed for a given response pattern in a verbal autopsy, and this sum (score provides the basis for predicting the cause of death in a dataset. We implemented this algorithm and evaluated the method's predictive ability, both in terms of chance-corrected concordance at the individual cause assignment level and in terms of CSMF accuracy at the population level. The analysis was conducted separately for adult, child, and neonatal verbal autopsies across 500 pairs of train-test validation verbal autopsy data. Results Tariff is capable of outperforming physician-certified verbal autopsy in most cases. In terms of chance-corrected concordance, the method achieves 44.5% in adults, 39% in children, and 23.9% in neonates. CSMF accuracy was 0.745 in adults, 0.709 in children, and 0.679 in neonates. Conclusions Verbal autopsies can be an efficient means of obtaining cause of death data, and Tariff provides an intuitive, reliable method for generating individual cause assignment and CSMFs. The method is transparent and flexible and can be readily implemented by users without training in statistics or computer science.

  1. Stretchable and High-Performance Supercapacitors with Crumpled Graphene Papers

    Science.gov (United States)

    Zang, Jianfeng; Cao, Changyong; Feng, Yaying; Liu, Jie; Zhao, Xuanhe

    2014-10-01

    Fabrication of unconventional energy storage devices with high stretchability and performance is challenging, but critical to practical operations of fully power-independent stretchable electronics. While supercapacitors represent a promising candidate for unconventional energy-storage devices, existing stretchable supercapacitors are limited by their low stretchability, complicated fabrication process, and high cost. Here, we report a simple and low-cost method to fabricate extremely stretchable and high-performance electrodes for supercapacitors based on new crumpled-graphene papers. Electrolyte-mediated-graphene paper bonded on a compliant substrate can be crumpled into self-organized patterns by harnessing mechanical instabilities in the graphene paper. As the substrate is stretched, the crumpled patterns unfold, maintaining high reliability of the graphene paper under multiple cycles of large deformation. Supercapacitor electrodes based on the crumpled graphene papers exhibit a unique combination of high stretchability (e.g., linear strain ~300%, areal strain ~800%), high electrochemical performance (e.g., specific capacitance ~196 F g-1), and high reliability (e.g., over 1000 stretch/relax cycles). An all-solid-state supercapacitor capable of large deformation is further fabricated to demonstrate practical applications of the crumpled-graphene-paper electrodes. Our method and design open a wide range of opportunities for manufacturing future energy-storage devices with desired deformability together with high performance.

  2. Stretchable and High-Performance Supercapacitors with Crumpled Graphene Papers

    Science.gov (United States)

    Zang, Jianfeng; Cao, Changyong; Feng, Yaying; Liu, Jie; Zhao, Xuanhe

    2014-01-01

    Fabrication of unconventional energy storage devices with high stretchability and performance is challenging, but critical to practical operations of fully power-independent stretchable electronics. While supercapacitors represent a promising candidate for unconventional energy-storage devices, existing stretchable supercapacitors are limited by their low stretchability, complicated fabrication process, and high cost. Here, we report a simple and low-cost method to fabricate extremely stretchable and high-performance electrodes for supercapacitors based on new crumpled-graphene papers. Electrolyte-mediated-graphene paper bonded on a compliant substrate can be crumpled into self-organized patterns by harnessing mechanical instabilities in the graphene paper. As the substrate is stretched, the crumpled patterns unfold, maintaining high reliability of the graphene paper under multiple cycles of large deformation. Supercapacitor electrodes based on the crumpled graphene papers exhibit a unique combination of high stretchability (e.g., linear strain ~300%, areal strain ~800%), high electrochemical performance (e.g., specific capacitance ~196 F g−1), and high reliability (e.g., over 1000 stretch/relax cycles). An all-solid-state supercapacitor capable of large deformation is further fabricated to demonstrate practical applications of the crumpled-graphene-paper electrodes. Our method and design open a wide range of opportunities for manufacturing future energy-storage devices with desired deformability together with high performance. PMID:25270673

  3. A robust, simple genotyping-by-sequencing (GBS approach for high diversity species.

    Directory of Open Access Journals (Sweden)

    Robert J Elshire

    Full Text Available Advances in next generation technologies have driven the costs of DNA sequencing down to the point that genotyping-by-sequencing (GBS is now feasible for high diversity, large genome species. Here, we report a procedure for constructing GBS libraries based on reducing genome complexity with restriction enzymes (REs. This approach is simple, quick, extremely specific, highly reproducible, and may reach important regions of the genome that are inaccessible to sequence capture approaches. By using methylation-sensitive REs, repetitive regions of genomes can be avoided and lower copy regions targeted with two to three fold higher efficiency. This tremendously simplifies computationally challenging alignment problems in species with high levels of genetic diversity. The GBS procedure is demonstrated with maize (IBM and barley (Oregon Wolfe Barley recombinant inbred populations where roughly 200,000 and 25,000 sequence tags were mapped, respectively. An advantage in species like barley that lack a complete genome sequence is that a reference map need only be developed around the restriction sites, and this can be done in the process of sample genotyping. In such cases, the consensus of the read clusters across the sequence tagged sites becomes the reference. Alternatively, for kinship analyses in the absence of a reference genome, the sequence tags can simply be treated as dominant markers. Future application of GBS to breeding, conservation, and global species and population surveys may allow plant breeders to conduct genomic selection on a novel germplasm or species without first having to develop any prior molecular tools, or conservation biologists to determine population structure without prior knowledge of the genome or diversity in the species.

  4. Simple Models for the Performance Evaluation of a Class of Two-Hop Relay Protocols

    NARCIS (Netherlands)

    Al Hanbali, Ahmad; Kherani, Arzad A.; Nain, Philippe

    2007-01-01

    We evaluate the performance of a class of two-hop relay protocols for mobile ad hoc networks. The interest is on the multicopy two-hop relay (MTR) protocol, where the source may generate multiple copies of a packet and use relay nodes to deliver the packet (or a copy) to its destination, and on the

  5. Simple models for the performance evaluation of a class of two-hop relay protocols

    NARCIS (Netherlands)

    Al Hanbali, A.; Kherani, A.A.; Nain, P.; Akyildiz, I.F.; Sivakumar, R.; Ekici, E.; Cavalcante de Oliveira, J.; McNair, J.

    2007-01-01

    We evaluate the performance of a class of two-hop relay protocols for mobile ad hoc networks. The interest is on the multicopy two-hop relay (MTR) protocol, where the source may generate multiple copies of a packet and use relay nodes to deliver the packet (or a copy) to its destination, and on the

  6. The New Jersey Performance Management System: A State System and Uses of Simple Measures.

    Science.gov (United States)

    Kamis-Gould, Edna

    1987-01-01

    The New Jersey Performance Management System (PMS) is a major mechanism used by the leadership of the New Jersey Division of Mental Health and Hospitals to contract for, monitor, and manage community mental health services. This paper describes PMS, its components, implementation, and limitations. (Author/LMO)

  7. Value-Added Funding: A Simple, Easy-to-Understand Model to Reward Performance. DO THIS!

    Science.gov (United States)

    Complete College America, 2012

    2012-01-01

    The mere mention of so-called "performance funding" makes college presidents and the higher education community nervous. It's an understandable reaction to a concept that too often results in an overly complex outcome. Still, the basic principle of "investing the limited resources states have in the results they want" is fundamentally sound--and…

  8. High performance liquid chromatographic determination of ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-02-08

    ) high performance liquid chromatography (HPLC) grade .... applications. These are important requirements if the reagent is to be applicable to on-line pre or post column derivatisation in a possible automation of the analytical.

  9. Analog circuit design designing high performance amplifiers

    CERN Document Server

    Feucht, Dennis

    2010-01-01

    The third volume Designing High Performance Amplifiers applies the concepts from the first two volumes. It is an advanced treatment of amplifier design/analysis emphasizing both wideband and precision amplification.

  10. High-performance computing using FPGAs

    CERN Document Server

    Benkrid, Khaled

    2013-01-01

    This book is concerned with the emerging field of High Performance Reconfigurable Computing (HPRC), which aims to harness the high performance and relative low power of reconfigurable hardware–in the form Field Programmable Gate Arrays (FPGAs)–in High Performance Computing (HPC) applications. It presents the latest developments in this field from applications, architecture, and tools and methodologies points of view. We hope that this work will form a reference for existing researchers in the field, and entice new researchers and developers to join the HPRC community.  The book includes:  Thirteen application chapters which present the most important application areas tackled by high performance reconfigurable computers, namely: financial computing, bioinformatics and computational biology, data search and processing, stencil computation e.g. computational fluid dynamics and seismic modeling, cryptanalysis, astronomical N-body simulation, and circuit simulation.     Seven architecture chapters which...

  11. Embedded High Performance Scalable Computing Systems

    National Research Council Canada - National Science Library

    Ngo, David

    2003-01-01

    The Embedded High Performance Scalable Computing Systems (EHPSCS) program is a cooperative agreement between Sanders, A Lockheed Martin Company and DARPA that ran for three years, from Apr 1995 - Apr 1998...

  12. Gradient High Performance Liquid Chromatography Method ...

    African Journals Online (AJOL)

    Purpose: To develop a gradient high performance liquid chromatography (HPLC) method for the simultaneous determination of phenylephrine (PHE) and ibuprofen (IBU) in solid ..... nimesulide, phenylephrine. Hydrochloride, chlorpheniramine maleate and caffeine anhydrous in pharmaceutical dosage form. Acta Pol.

  13. Highlighting High Performance: Whitman Hanson Regional High School; Whitman, Massachusetts

    Energy Technology Data Exchange (ETDEWEB)

    2006-06-01

    This brochure describes the key high-performance building features of the Whitman-Hanson Regional High School. The brochure was paid for by the Massachusetts Technology Collaborative as part of their Green Schools Initiative. High-performance features described are daylighting and energy-efficient lighting, indoor air quality, solar and wind energy, building envelope, heating and cooling systems, water conservation, and acoustics. Energy cost savings are also discussed.

  14. A simple highly sensitive and selective aptamer-based colorimetric sensor for environmental toxins microcystin-LR in water samples.

    Science.gov (United States)

    Li, Xiuyan; Cheng, Ruojie; Shi, Huijie; Tang, Bo; Xiao, Hanshuang; Zhao, Guohua

    2016-03-05

    A simple and highly sensitive aptamer-based colorimetric sensor was developed for selective detection of Microcystin-LR (MC-LR). The aptamer (ABA) was employed as recognition element which could bind MC-LR with high-affinity, while gold nanoparticles (AuNPs) worked as sensing materials whose plasma resonance absorption peaks red shifted upon binding of the targets at a high concentration of sodium chloride. With the addition of MC-LR, the random coil aptamer adsorbed on Au NPs altered into regulated structure to form MC-LR-aptamer complexes and broke away from the surface of Au NPs, leading to the aggregation of AuNPs, and the color converted from red to blue due to the interparticle plasmon coupling. Results showed that our aptamer-based colorimetric sensor exhibited rapid and sensitive detection performance for MC-LR with linear range from 0.5 nM to 7.5 μM and the detection limit reached 0.37 nM. Meanwhile, the pollutants usually coexisting with MC-LR in pollutant water samples had not demonstrated disturbance for detecting of MC-LR. The mechanism was also proposed suggesting that high affinity interaction between aptamer and MC-LR significantly enhanced the sensitivity and selectivity for MC-LR detection. Besides, the established method was utilized in analyzing real water samples and splendid sensitivity and selectivity were obtained as well. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. High performance computing in Windows Azure cloud

    OpenAIRE

    Ambruš, Dejan

    2013-01-01

    High performance, security, availability, scalability, flexibility and lower costs of maintenance have essentially contributed to the growing popularity of cloud computing in all spheres of life, especially in business. In fact cloud computing offers even more than this. With usage of virtual computing clusters a runtime environment for high performance computing can be efficiently implemented also in a cloud. There are many advantages but also some disadvantages of cloud computing, some ...

  16. High-performance computing — an overview

    Science.gov (United States)

    Marksteiner, Peter

    1996-08-01

    An overview of high-performance computing (HPC) is given. Different types of computer architectures used in HPC are discussed: vector supercomputers, high-performance RISC processors, various parallel computers like symmetric multiprocessors, workstation clusters, massively parallel processors. Software tools and programming techniques used in HPC are reviewed: vectorizing compilers, optimization and vector tuning, optimization for RISC processors; parallel programming techniques like shared-memory parallelism, message passing and data parallelism; and numerical libraries.

  17. High density flux of Co nanoparticles produced by a simple gas aggregation apparatus

    Energy Technology Data Exchange (ETDEWEB)

    Landi, G. T.; Romero, S. A.; Santos, A. D. [Departamento de Fisica dos Materiais e Mecanica, Laboratorio de Materiais Magneticos, Instituto de Fisica, Universidade de Sao Paulo, Caixa Postal 66318, 05314-970 Sao Paulo, SP (Brazil)

    2010-03-15

    Gas aggregation is a well known method used to produce clusters of different materials with good size control, reduced dispersion, and precise stoichiometry. The cost of these systems is relatively high and they are generally dedicated apparatuses. Furthermore, the usual sample production speed of these systems is not as fast as physical vapor deposition devices posing a problem when thick samples are needed. In this paper we describe the development of a multipurpose gas aggregation system constructed as an adaptation to a magnetron sputtering system. The cost of this adaptation is negligible and its installation and operation are both remarkably simple. The gas flow for flux in the range of 60-130 SCCM (SCCM denotes cubic centimeter per minute at STP) is able to completely collimate all the sputtered material, producing spherical nanoparticles. Co nanoparticles were produced and characterized using electron microscopy techniques and Rutherford back-scattering analysis. The size of the particles is around 10 nm with around 75 nm/min of deposition rate at the center of a Gaussian profile nanoparticle beam.

  18. High density flux of Co nanoparticles produced by a simple gas aggregation apparatus

    International Nuclear Information System (INIS)

    Landi, G. T.; Romero, S. A.; Santos, A. D.

    2010-01-01

    Gas aggregation is a well known method used to produce clusters of different materials with good size control, reduced dispersion, and precise stoichiometry. The cost of these systems is relatively high and they are generally dedicated apparatuses. Furthermore, the usual sample production speed of these systems is not as fast as physical vapor deposition devices posing a problem when thick samples are needed. In this paper we describe the development of a multipurpose gas aggregation system constructed as an adaptation to a magnetron sputtering system. The cost of this adaptation is negligible and its installation and operation are both remarkably simple. The gas flow for flux in the range of 60-130 SCCM (SCCM denotes cubic centimeter per minute at STP) is able to completely collimate all the sputtered material, producing spherical nanoparticles. Co nanoparticles were produced and characterized using electron microscopy techniques and Rutherford back-scattering analysis. The size of the particles is around 10 nm with around 75 nm/min of deposition rate at the center of a Gaussian profile nanoparticle beam.

  19. Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture.

    Science.gov (United States)

    DeQuach, Jessica A; Mezzano, Valeria; Miglani, Amar; Lange, Stephan; Keller, Gordon M; Sheikh, Farah; Christman, Karen L

    2010-09-27

    The native extracellular matrix (ECM) consists of a highly complex, tissue-specific network of proteins and polysaccharides, which help regulate many cellular functions. Despite the complex nature of the ECM, in vitro cell-based studies traditionally assess cell behavior on single ECM component substrates, which do not adequately mimic the in vivo extracellular milieu. We present a simple approach for developing naturally derived ECM coatings for cell culture that provide important tissue-specific cues unlike traditional cell culture coatings, thereby enabling the maturation of committed C2C12 skeletal myoblast progenitors and human embryonic stem cells differentiated into cardiomyocytes. Here we show that natural muscle-specific coatings can (i) be derived from decellularized, solubilized adult porcine muscle, (ii) contain a complex mixture of ECM components including polysaccharides, (iii) adsorb onto tissue culture plastic and (iv) promote cell maturation of committed muscle progenitor and stem cells. This versatile method can create tissue-specific ECM coatings, which offer a promising platform for cell culture to more closely mimic the mature in vivo ECM microenvironment.

  20. Fast and simple high-capacity quantum cryptography with error detection

    Science.gov (United States)

    Lai, Hong; Luo, Ming-Xing; Pieprzyk, Josef; Zhang, Jun; Pan, Lei; Li, Shudong; Orgun, Mehmet A.

    2017-04-01

    Quantum cryptography is commonly used to generate fresh secure keys with quantum signal transmission for instant use between two parties. However, research shows that the relatively low key generation rate hinders its practical use where a symmetric cryptography component consumes the shared key. That is, the security of the symmetric cryptography demands frequent rate of key updates, which leads to a higher consumption of the internal one-time-pad communication bandwidth, since it requires the length of the key to be as long as that of the secret. In order to alleviate these issues, we develop a matrix algorithm for fast and simple high-capacity quantum cryptography. Our scheme can achieve secure private communication with fresh keys generated from Fibonacci- and Lucas- valued orbital angular momentum (OAM) states for the seed to construct recursive Fibonacci and Lucas matrices. Moreover, the proposed matrix algorithm for quantum cryptography can ultimately be simplified to matrix multiplication, which is implemented and optimized in modern computers. Most importantly, considerably information capacity can be improved effectively and efficiently by the recursive property of Fibonacci and Lucas matrices, thereby avoiding the restriction of physical conditions, such as the communication bandwidth.

  1. A Simple and Sensitive High-Content Assay for the Characterization of Antiproliferative Therapeutic Antibodies.

    Science.gov (United States)

    Stengl, Andreas; Hörl, David; Leonhardt, Heinrich; Helma, Jonas

    2017-03-01

    Monoclonal antibodies (mAbs) have become a central class of therapeutic agents in particular as antiproliferative compounds. Their often complex modes of action require sensitive assays during early, functional characterization. Current cell-based proliferation assays often detect metabolites that are indicative of metabolic activity but do not directly account for cell proliferation. Measuring DNA replication by incorporation of base analogues such as 5-bromo-2'-deoxyuridine (BrdU) fills this analytical gap but was previously restricted to bulk effect characterization in enzyme-linked immunosorbent assay formats. Here, we describe a cell-based assay format for the characterization of antiproliferative mAbs regarding potency and mode of action in a single experiment. The assay makes use of single cell-based high-content-analysis (HCA) for the reliable quantification of replicating cells and DNA content via 5-ethynyl-2'-deoxyuridine (EdU) and 4',6-diamidino-2-phenylindole (DAPI), respectively, as sensitive measures of antiproliferative mAb activity. We used trastuzumab, an antiproliferative therapeutic antibody interfering with HER2 cell surface receptor-mediated growth signal transduction, and HER2-overexpressing cell lines BT474 and SKBR3 to demonstrate up to 10-fold signal-to-background (S/B) ratios for treated versus untreated cells and a shift in cell cycle profiles indicating antibody-induced cell cycle arrest. The assay is simple, cost-effective, and sensitive, providing a cell-based format for preclinical characterization of therapeutic mAbs.

  2. Fast and simple high-capacity quantum cryptography with error detection.

    Science.gov (United States)

    Lai, Hong; Luo, Ming-Xing; Pieprzyk, Josef; Zhang, Jun; Pan, Lei; Li, Shudong; Orgun, Mehmet A

    2017-04-13

    Quantum cryptography is commonly used to generate fresh secure keys with quantum signal transmission for instant use between two parties. However, research shows that the relatively low key generation rate hinders its practical use where a symmetric cryptography component consumes the shared key. That is, the security of the symmetric cryptography demands frequent rate of key updates, which leads to a higher consumption of the internal one-time-pad communication bandwidth, since it requires the length of the key to be as long as that of the secret. In order to alleviate these issues, we develop a matrix algorithm for fast and simple high-capacity quantum cryptography. Our scheme can achieve secure private communication with fresh keys generated from Fibonacci- and Lucas- valued orbital angular momentum (OAM) states for the seed to construct recursive Fibonacci and Lucas matrices. Moreover, the proposed matrix algorithm for quantum cryptography can ultimately be simplified to matrix multiplication, which is implemented and optimized in modern computers. Most importantly, considerably information capacity can be improved effectively and efficiently by the recursive property of Fibonacci and Lucas matrices, thereby avoiding the restriction of physical conditions, such as the communication bandwidth.

  3. Governance among Malaysian high performing companies

    Directory of Open Access Journals (Sweden)

    Asri Marsidi

    2016-07-01

    Full Text Available Well performed companies have always been linked with effective governance which is generally reflected through effective board of directors. However many issues concerning the attributes for effective board of directors remained unresolved. Nowadays diversity has been perceived as able to influence the corporate performance due to the likelihood of meeting variety of needs and demands from diverse customers and clients. The study therefore aims to provide a fundamental understanding on governance among high performing companies in Malaysia.

  4. High-performance OPCPA laser system

    International Nuclear Information System (INIS)

    Zuegel, J.D.; Bagnoud, V.; Bromage, J.; Begishev, I.A.; Puth, J.

    2006-01-01

    Optical parametric chirped-pulse amplification (OPCPA) is ideally suited for amplifying ultra-fast laser pulses since it provides broadband gain across a wide range of wavelengths without many of the disadvantages of regenerative amplification. A high-performance OPCPA system has been demonstrated as a prototype for the front end of the OMEGA Extended Performance (EP) Laser System. (authors)

  5. High-performance OPCPA laser system

    Energy Technology Data Exchange (ETDEWEB)

    Zuegel, J.D.; Bagnoud, V.; Bromage, J.; Begishev, I.A.; Puth, J. [Rochester Univ., Lab. for Laser Energetics, NY (United States)

    2006-06-15

    Optical parametric chirped-pulse amplification (OPCPA) is ideally suited for amplifying ultra-fast laser pulses since it provides broadband gain across a wide range of wavelengths without many of the disadvantages of regenerative amplification. A high-performance OPCPA system has been demonstrated as a prototype for the front end of the OMEGA Extended Performance (EP) Laser System. (authors)

  6. Comparing Dutch and British high performing managers

    NARCIS (Netherlands)

    Waal, A.A. de; Heijden, B.I.J.M. van der; Selvarajah, C.; Meyer, D.

    2016-01-01

    National cultures have a strong influence on the performance of organizations and should be taken into account when studying the traits of high performing managers. At the same time, many studies that focus upon the attributes of successful managers show that there are attributes that are similar

  7. Enhanced liposomal vaccine formulation and performance: simple physicochemical and immunological approaches.

    Science.gov (United States)

    de Almeida Silva, Vanessa; Sayoko Takata, Célia; Sant'Anna, Osvaldo A; Carlos Lopes, Antônio; Soares de Araujo, Pedro; Helena Bueno da Costa, Maria

    2006-01-01

    antibody (245 higher than the control) produced by those mice injected with lipossomal formulation at pH 4.0 with the booster done 138 days after priming. The simple change on lipossomal pH formulation and timing of the booster enhanced both antibody production and selectivity.

  8. Simple catalytic cell for restoring He leak detector sensitivity on vacuum systems with high D2 backgrounds

    International Nuclear Information System (INIS)

    Busath, J.; Chiu, H.K.

    1998-12-01

    The DIII-D National Fusion Facility at General Atomics focuses on plasma physics and fusion energy science. The DIII-D tokamak is a 35 m 3 toroidal vacuum vessel with over 200 ports for diagnostic instrumentation, cryogenics, microwave heating, and four large neutral beam injectors. Maintaining vacuum in the 10 -8 Torr range is crucial for producing high performance plasma discharges. He leak checking the DIII-D tokamak and the neutral beamlines has historically been difficult. D 2 is used as the fuel gas in most plasma discharges and neutral beams. After plasma operations, D 2 out-gassing from the torus walls and internal beamline components can exceed 10 -4 std cc/s. The mass of the D 2 molecule (4.028 u) is indistinguishable from that of the He atom (4.003 u) to a standard mass spectrometer leak detector. High levels of D 2 reduce leak detector sensitivity and effectively mask the He trace gas signal rendering normal leak checking techniques ineffective. A simple apparatus was developed at GA to address these problems. It consists of a palladium based catalyst cell and associated valves and piping placed in series with the leak detector. This reduces the D 2 throughput by a factor greater than 10,000, restoring leak detector sensitivity. This paper will briefly discuss the development of the cell, the physical processes involved, the tests performed to quantify and optimize the processes, and the operational results at DIII-D

  9. Hydrazine Determination in Sludge Samples by High Performance Liquid Chromatography

    Energy Technology Data Exchange (ETDEWEB)

    G. Elias; G. A. Park

    2006-02-01

    A high-performance liquid chromatographic method using ultraviolet (UV) detection was developed to detect and quantify hydrazine in a variety of environmental matrices. The method was developed primarily for sludge samples, but it is also applicable to soil and water samples. The hydrazine in the matrices was derivatized to their hydrazones with benzaldehyde. The derivatized hydrazones were separated using high performance liquid chromatography (HPLC) with a reversed-phase C-18 column in an isocratic mode with methanol-water (95:5, v/v), and detected with UV detection at 313 nm. The detection limit (25 ml) for the new analytical method is 0.0067 mg ml-1of hydrazine. Hydrazine showed low recovery in soil samples because components in soil oxidized hydrazine. Sludge samples that contained relatively high soil content also showed lower recovery. The technique is relatively simple and cost-effective, and is applicable for hydrazine analysis in different environmental matrices.

  10. Designing high-Performance layered thermoelectric materials through orbital engineering

    DEFF Research Database (Denmark)

    Zhang, Jiawei; Song, Lirong; Madsen, Georg K. H.

    2016-01-01

    Thermoelectric technology, which possesses potential application in recycling industrial waste heat as energy, calls for novel high-performance materials. The systematic exploration of novel thermoelectric materials with excellent electronic transport properties is severely hindered by limited...... insight into the underlying bonding orbitals of atomic structures. Here we propose a simple yet successful strategy to discover and design high-performance layered thermoelectric materials through minimizing the crystal field splitting energy of orbitals to realize high orbital degeneracy. The approach...... naturally leads to design maps for optimizing the thermoelectric power factor through forming solid solutions and biaxial strain. Using this approach, we predict a series of potential thermoelectric candidates from layered CaAl2Si2-type Zintl compounds. Several of them contain nontoxic, low-cost and earth...

  11. Visualization of intracranial vessel anatomy using high resolution MRI and a simple image fusion technique

    International Nuclear Information System (INIS)

    Nasel, C.

    2005-01-01

    A new technique for fusion and 3D viewing of high resolution magnetic resonance (MR) angiography and morphological MR sequences is reported. Scanning and image fusion was possible within 20 min on a standard 1.5 T MR-scanner. The procedure was successfully performed in 10 consecutive cases with excellent visualization of wall and luminal aspects of the intracranial segments of the internal carotid artery, the vertebrobasilar system and the anterior, middle and posterior cerebral artery

  12. Visualization of intracranial vessel anatomy using high resolution MRI and a simple image fusion technique

    Energy Technology Data Exchange (ETDEWEB)

    Nasel, C. [Division of Neuroradiology, Department of Radiology, Medical University of Vienna, Waehringerguertel 18-20, A-1090 Vienna (Austria)]. E-mail: christian.nasel@perfusion.at

    2005-04-01

    A new technique for fusion and 3D viewing of high resolution magnetic resonance (MR) angiography and morphological MR sequences is reported. Scanning and image fusion was possible within 20 min on a standard 1.5 T MR-scanner. The procedure was successfully performed in 10 consecutive cases with excellent visualization of wall and luminal aspects of the intracranial segments of the internal carotid artery, the vertebrobasilar system and the anterior, middle and posterior cerebral artery.

  13. Highly efficient silver patterning without photo-resist using simple silver precursors

    International Nuclear Information System (INIS)

    Byun, Younghun; Hwang, Eoc-Chae; Lee, Sang-Yun; Lyu, Yi-Yeol; Yim, Jin-Heong; Kim, Jin-Young; Chang, Seok; Pu, Lyong Sun; Kim, Ji Man

    2005-01-01

    Highly efficient method for silver patterning without photo-resist was developed by using high photosensitive organo-silver precursors, which were prepared by a simple reaction of silver salts and excess of amines. The FT-IR and GC-MS spectra were recorded depending on UV exposure time, for (n-PrNH 2 )Ag(NO 3 ).0.5MeCN and (n-PrNH 2 )Ag(NO 2 ).0.5MeCN, to understand the photolysis mechanism. The results indicate not only dissociation of coordinated amine and acetonitrile, but also decomposition of corresponding anion upon UV irradiation. When a precursor thin film was exposed to broadband UV irradiation, a partially reduced and insoluble silver species were formed within several minutes. After development, the irradiated areas were treated with a reducing agent to obtain pure metallic patterns. Subsequently, annealing step was followed at 100-350 deg. C to increase the adhesion of interface and cohesion of silver particles. The line resolution of 5 μm was obtained by the present silver precursors. Film thickness was also controllable from 50 to 250 nm by repetition of the above procedure. The average electrical conductivity was in the range of 3-43 Ω cm, measured by four-point probe technique. AES depth profile of the silver pattern thus obtained showed carbon and oxygen contents are less than 1% through the whole range. Even though sulfur contaminant exists on the surface, it was believed that nearly pure silver pattern was generated

  14. A simple differential steady-state method to measure the thermal conductivity of solid bulk materials with high accuracy.

    Science.gov (United States)

    Kraemer, D; Chen, G

    2014-02-01

    Accurate measurements of thermal conductivity are of great importance for materials research and development. Steady-state methods determine thermal conductivity directly from the proportionality between heat flow and an applied temperature difference (Fourier Law). Although theoretically simple, in practice, achieving high accuracies with steady-state methods is challenging and requires rather complex experimental setups due to temperature sensor uncertainties and parasitic heat loss. We developed a simple differential steady-state method in which the sample is mounted between an electric heater and a temperature-controlled heat sink. Our method calibrates for parasitic heat losses from the electric heater during the measurement by maintaining a constant heater temperature close to the environmental temperature while varying the heat sink temperature. This enables a large signal-to-noise ratio which permits accurate measurements of samples with small thermal conductance values without an additional heater calibration measurement or sophisticated heater guards to eliminate parasitic heater losses. Additionally, the differential nature of the method largely eliminates the uncertainties of the temperature sensors, permitting measurements with small temperature differences, which is advantageous for samples with high thermal conductance values and/or with strongly temperature-dependent thermal conductivities. In order to accelerate measurements of more than one sample, the proposed method allows for measuring several samples consecutively at each temperature measurement point without adding significant error. We demonstrate the method by performing thermal conductivity measurements on commercial bulk thermoelectric Bi2Te3 samples in the temperature range of 30-150 °C with an error below 3%.

  15. High Performance Work Systems for Online Education

    Science.gov (United States)

    Contacos-Sawyer, Jonna; Revels, Mark; Ciampa, Mark

    2010-01-01

    The purpose of this paper is to identify the key elements of a High Performance Work System (HPWS) and explore the possibility of implementation in an online institution of higher learning. With the projected rapid growth of the demand for online education and its importance in post-secondary education, providing high quality curriculum, excellent…

  16. Teacher Accountability at High Performing Charter Schools

    Science.gov (United States)

    Aguirre, Moises G.

    2016-01-01

    This study will examine the teacher accountability and evaluation policies and practices at three high performing charter schools located in San Diego County, California. Charter schools are exempted from many laws, rules, and regulations that apply to traditional school systems. By examining the teacher accountability systems at high performing…

  17. Surface pressure model for simple delta wings at high angles of attack

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    polynomial function approach, splines with limited support and neural network models are ... for thin streamlined bodies, the normal force and pitching moment .... eter, a simple point vortex over an infinite plate is used to derive some results.

  18. Development of Simple Drying Model for Performance Prediction of Solar Dryer: Theoretical Analysis

    DEFF Research Database (Denmark)

    Singh, Shobhana; Kumar, Subodh

    2012-01-01

    An analytical moisture diffusion model which considers the influence of external resistance to mass transfer is developed to predict thermal performance of dryer system. The moisture diffusion coefficient, Deff that is necessary to evaluate the prediction model has been determined in terms...... of experimental drying parameters. A laboratory model of mixed-mode solar dryer system is tested with cylindrical potato samples of thickness 5 and 18 mm under simulated indoor conditions. The potato samples were dried at a constant absorbed thermal energy of 750 W/m2 and air mass flow rate of 0.011 kg...

  19. Simple method of calculating the transient thermal performance of composite material and its applicable condition

    Institute of Scientific and Technical Information of China (English)

    张寅平; 梁新刚; 江忆; 狄洪发; 宁志军

    2000-01-01

    Degree of mixing of composite material is defined and the condition of using the effective thermal diffusivity for calculating the transient thermal performance of composite material is studied. The analytical result shows that for a prescribed precision of temperature, there is a condition under which the transient temperature distribution in composite material can be calculated by using the effective thermal diffusivity. As illustration, for the composite material whose temperatures of both ends are constant, the condition is presented and the factors affecting the relative error of calculated temperature of composite materials by using effective thermal diffusivity are discussed.

  20. Advanced high performance solid wall blanket concepts

    International Nuclear Information System (INIS)

    Wong, C.P.C.; Malang, S.; Nishio, S.; Raffray, R.; Sagara, A.

    2002-01-01

    First wall and blanket (FW/blanket) design is a crucial element in the performance and acceptance of a fusion power plant. High temperature structural and breeding materials are needed for high thermal performance. A suitable combination of structural design with the selected materials is necessary for D-T fuel sufficiency. Whenever possible, low afterheat, low chemical reactivity and low activation materials are desired to achieve passive safety and minimize the amount of high-level waste. Of course the selected fusion FW/blanket design will have to match the operational scenarios of high performance plasma. The key characteristics of eight advanced high performance FW/blanket concepts are presented in this paper. Design configurations, performance characteristics, unique advantages and issues are summarized. All reviewed designs can satisfy most of the necessary design goals. For further development, in concert with the advancement in plasma control and scrape off layer physics, additional emphasis will be needed in the areas of first wall coating material selection, design of plasma stabilization coils, consideration of reactor startup and transient events. To validate the projected performance of the advanced FW/blanket concepts the critical element is the need for 14 MeV neutron irradiation facilities for the generation of necessary engineering design data and the prediction of FW/blanket components lifetime and availability

  1. A simple approximation for the current-voltage characteristics of high-power, relativistic diodes

    Energy Technology Data Exchange (ETDEWEB)

    Ekdahl, Carl, E-mail: cekdahl@lanl.gov [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)

    2016-06-15

    A simple approximation for the current-voltage characteristics of a relativistic electron diode is presented. The approximation is accurate from non-relativistic through relativistic electron energies. Although it is empirically developed, it has many of the fundamental properties of the exact diode solutions. The approximation is simple enough to be remembered and worked on almost any pocket calculator, so it has proven to be quite useful on the laboratory floor.

  2. Performance on a simple response time task: Is sleep or work more important for miners?

    Science.gov (United States)

    Ferguson, Sally A; Paech, Gemma M; Dorrian, Jillian; Roach, Gregory D; Jay, Sarah M

    2011-01-01

    The purpose of the current study was to investigate the impact of work- and sleep-related factors on an objective measure of response time in a field setting. Thirty-five mining operators working 12-h shift patterns completed daily sleep and work diaries, wore activity monitors continuously and completed palm-based psychomotor vigilance tests (palmPVT) at the start and end of each shift. Linear mixed models were used to test the main effects on response time of roster, timing of test, sleep history and prior wake. The time at which the test occurred was a significant predictor of response time (F₃(,)₄₀₃(.)₄ = 6.72, p times than the start of night shifts, and the start or end of day shifts. Further, the amount of sleep obtained in the 24h prior to the test was also a significant predictor of response time (F₃(,)₄₀₇(.)₀ = 3.05, p time indicative of performance impairments. Of more interest however is that immediate sleep history was also predictive of changes in response time with lower amounts of prior sleep related to slower response times. The current data provides further evidence that sleep is a primary mediator of performance, independent of roster pattern. Copyright © 2010 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  3. A Simple Ensemble Simulation Technique for Assessment of Future Variations in Specific High-Impact Weather Events

    Science.gov (United States)

    Taniguchi, Kenji

    2018-04-01

    To investigate future variations in high-impact weather events, numerous samples are required. For the detailed assessment in a specific region, a high spatial resolution is also required. A simple ensemble simulation technique is proposed in this paper. In the proposed technique, new ensemble members were generated from one basic state vector and two perturbation vectors, which were obtained by lagged average forecasting simulations. Sensitivity experiments with different numbers of ensemble members, different simulation lengths, and different perturbation magnitudes were performed. Experimental application to a global warming study was also implemented for a typhoon event. Ensemble-mean results and ensemble spreads of total precipitation, atmospheric conditions showed similar characteristics across the sensitivity experiments. The frequencies of the maximum total and hourly precipitation also showed similar distributions. These results indicate the robustness of the proposed technique. On the other hand, considerable ensemble spread was found in each ensemble experiment. In addition, the results of the application to a global warming study showed possible variations in the future. These results indicate that the proposed technique is useful for investigating various meteorological phenomena and the impacts of global warming. The results of the ensemble simulations also enable the stochastic evaluation of differences in high-impact weather events. In addition, the impacts of a spectral nudging technique were also examined. The tracks of a typhoon were quite different between cases with and without spectral nudging; however, the ranges of the tracks among ensemble members were comparable. It indicates that spectral nudging does not necessarily suppress ensemble spread.

  4. A simple approach to enhance the performance of complex-coefficient filter-based PLL in grid-connected applications

    DEFF Research Database (Denmark)

    Ramezani, Malek; Golestan, Saeed; Li, Shuhui

    2018-01-01

    In recent years, a large number of three-phase phase-locked loops (PLLs) have been developed. One of the most popular ones is the complex coefficient filterbased PLL (CCF-PLL). The CCFs benefit from a sequence selective filtering ability and, hence, enable the CCF-PLL to selectively reject/extract...... disturbances before the PLL control loop while maintaining an acceptable dynamic behavior. The aim of this paper is presenting a simple yet effective approach to enhance the standard CCF-PLL performance without requiring any additional computational load....

  5. Fabrication of Simple Indoor Air Haze Purifier using Domestic Discarded Substances and Its Haze Removal Performance

    Science.gov (United States)

    Wang, Zhou; Cao, Haoshu; Zhao, Shuang

    2018-01-01

    Based on the concept of circular economy, discarded plastic bottles stuffed with discarded cotton, clothing and sofa cushion were used as pre-filter to remove big particles (dust and coal dust) in air and 4 L tap water in discarded plastic bottle was worked as an absorbing medium to dissolve the water soluble ions in air (SO4 2-, NO3-, NH4+, Cl- and Ca2+). Moreover, the internet control design was used in this homemade indoor air haze purifier to achieve the performance of remote control and intelligent management. The experimental results showed that this indoor air haze purifier can effectively reduce the level of indoor air haze and the air quality after 20 minutes treatment is higher than that of two commercial well-known air haze purifier

  6. A simple procedure to evaluate the performance of fats and oils at frying temperatures.

    Directory of Open Access Journals (Sweden)

    Barrera-Arellano, D.

    1997-08-01

    Full Text Available A standard procedure is proposed to evaluate the performance of fats and oils at frying temperatures, taking the advantages provided by the Rancimat apparatus, i. e., standard vessels, temperature correction and temperature homogenity in all vessels resulting from the particular characteristics of the heating block. The results obtained in oil samples of 8 g heated at 180° C for 10 h in triplicate gave coefficients of variation lower than 6% for total polar compounds and polymers. In case of limited amount of oil, it is additionally proposed to use only 2 g of sample provided that a similar surface-to-oil volume ratio is maintained, and coefficients of variation of the same order than those for 8 g samples were thus obtained. Advantages of the procedure as well as potential applications for evaluation of frying fats and oils are Included. As an example, the effect of α-tocopherol on performance of sunflower oils was analyzed.

    Se propone un procedimiento estándar para evaluar el comportamiento de aceites y grasas a temperaturas de fritura. En este procedimiento se utilizan las ventajas del aparato Rancimat, que permite el uso de tubos estándar, la corrección de la temperatura, en su caso, y la igualdad de temperatura en todos los tubos dadas las características del bloque de calentamiento. De los resultados obtenidos en muestras de 8 g de aceite calentadas a 180° C durante 10 h, analizadas por triplicado, se obtuvieron coeficientes de variación inferiores al 6% para la determinación de compuestos polares y polímeros. En caso de limitación en la cantidad de aceite, se propone utilizar 2 g de muestra, manteniendo similares valores para la relación superficie a volumen de aceite, lo que permite obtener valores de alteración y coeficientes de variación del mismo orden. Se analizan finalmente las ventajas globales del procedimiento y sus distintas posibilidades en la evaluación de grasas de fritura. Como ejemplo, se aplica el

  7. A simple and rapid method for the determination of taxol produced by fungal endophytes from medicinal plants using high performance thin layer chromatography%高效薄层色谱法快速测定由药用植物内生真菌产生的紫杉醇

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Taxol is an important anticancer drug used widely in the clinical field. In this study, some endophytic fungi were isolated from selected medicinal plants, and were screened for their potential in the production of taxol, using a rapid separation technique of high performance thin layer chromatography ( HPTLC ). Of the 20 screened fungi, only 13 fungal species produced taxol in the artificial culture medium.The results of HPTLC showed that the 13 fungal species had identical ultraviolet (UV) characteristics, positive reactivity with a spray reagent, yielding a blue spot, which turned to dark gray after 24 hours, and had Rf values identical to that of the authentic taxol. The amount of taxol was also quantified by comparing the peak area and the peak height of the fungal samples with those of authentic taxol.

  8. Application of experiential learning model using simple physical kit to increase attitude toward physics student senior high school in fluid

    Science.gov (United States)

    Johari, A. H.; Muslim

    2018-05-01

    Experiential learning model using simple physics kit has been implemented to get a picture of improving attitude toward physics senior high school students on Fluid. This study aims to obtain a description of the increase attitudes toward physics senior high school students. The research method used was quasi experiment with non-equivalent pretest -posttest control group design. Two class of tenth grade were involved in this research 28, 26 students respectively experiment class and control class. Increased Attitude toward physics of senior high school students is calculated using an attitude scale consisting of 18 questions. Based on the experimental class test average of 86.5% with the criteria of almost all students there is an increase and in the control class of 53.75% with the criteria of half students. This result shows that the influence of experiential learning model using simple physics kit can improve attitude toward physics compared to experiential learning without using simple physics kit.

  9. High performance bio-integrated devices

    Science.gov (United States)

    Kim, Dae-Hyeong; Lee, Jongha; Park, Minjoon

    2014-06-01

    In recent years, personalized electronics for medical applications, particularly, have attracted much attention with the rise of smartphones because the coupling of such devices and smartphones enables the continuous health-monitoring in patients' daily life. Especially, it is expected that the high performance biomedical electronics integrated with the human body can open new opportunities in the ubiquitous healthcare. However, the mechanical and geometrical constraints inherent in all standard forms of high performance rigid wafer-based electronics raise unique integration challenges with biotic entities. Here, we describe materials and design constructs for high performance skin-mountable bio-integrated electronic devices, which incorporate arrays of single crystalline inorganic nanomembranes. The resulting electronic devices include flexible and stretchable electrophysiology electrodes and sensors coupled with active electronic components. These advances in bio-integrated systems create new directions in the personalized health monitoring and/or human-machine interfaces.

  10. Designing a High Performance Parallel Personal Cluster

    OpenAIRE

    Kapanova, K. G.; Sellier, J. M.

    2016-01-01

    Today, many scientific and engineering areas require high performance computing to perform computationally intensive experiments. For example, many advances in transport phenomena, thermodynamics, material properties, computational chemistry and physics are possible only because of the availability of such large scale computing infrastructures. Yet many challenges are still open. The cost of energy consumption, cooling, competition for resources have been some of the reasons why the scientifi...

  11. vSphere high performance cookbook

    CERN Document Server

    Sarkar, Prasenjit

    2013-01-01

    vSphere High Performance Cookbook is written in a practical, helpful style with numerous recipes focusing on answering and providing solutions to common, and not-so common, performance issues and problems.The book is primarily written for technical professionals with system administration skills and some VMware experience who wish to learn about advanced optimization and the configuration features and functions for vSphere 5.1.

  12. Experimental investigation of simple solar radiation spectral model performances under a Mediterranean Algerian's climate

    International Nuclear Information System (INIS)

    Koussa, Mustapha; Saheb-Koussa, Djohra; Hadji, Seddik

    2017-01-01

    solar global components. Conversely, it is observed that it is less efficient in evaluating the horizontal diffuse components and its accuracy depends on several scattering phenomena, which are represented by scientists by means of constant values or expressions. The reasonable accuracy of the model and for it's simplicity make it for a number of solar applications. - Highlights: • Presentation of the retained spectral models. • An experimental investigation of the models performances is carried out. • Correlation relating the main local atmospheric constituent's is carried out. • The seasonal effect of the turbidity and water vapor on solar radiation is considered. • Presented model make it suitable for a number of solar applications.

  13. High performance parallel I/O

    CERN Document Server

    Prabhat

    2014-01-01

    Gain Critical Insight into the Parallel I/O EcosystemParallel I/O is an integral component of modern high performance computing (HPC), especially in storing and processing very large datasets to facilitate scientific discovery. Revealing the state of the art in this field, High Performance Parallel I/O draws on insights from leading practitioners, researchers, software architects, developers, and scientists who shed light on the parallel I/O ecosystem.The first part of the book explains how large-scale HPC facilities scope, configure, and operate systems, with an emphasis on choices of I/O har

  14. Self-Reported Versus Performance-Based Assessments of a Simple Mobility Task Among Older Adults in the Emergency Department.

    Science.gov (United States)

    Roedersheimer, Kyle M; Pereira, Greg F; Jones, Christopher W; Braz, Valerie A; Mangipudi, Sowmya A; Platts-Mills, Timothy F

    2016-02-01

    Accurate information about the mobility of independently living older adults is essential in determining whether they may be safely discharged home from the emergency department (ED). We assess the accuracy of self-reported ability to complete a simple mobility task among older ED patients. This was a cross-sectional study of cognitively intact patients aged 65 years and older who were neither nursing home residents nor critically ill, conducted in 2 academic EDs. Consenting participants were asked whether they could get out of bed, walk 10 feet, turn around, and get back in bed without assistance, and if not, whether they could perform this task with a cane, walker, or assistance. Each participant was then asked to perform the task and was provided with a mobility device or assistance as needed. Of 272 patients who met eligibility criteria and answered the physical task question, 161 (59%) said they could do the task unassisted, 45 (17%) said they could do it with a cane or walker, 21 (8%) said they could do it with assistance, and 45 (17%) said they would be unable to do it even with assistance. Among those who said they could do the task either with or without assistance and who were subsequently willing to attempt the task (N=172), discrepancies between self-reported ability and actual performance were common. Of those who said they could perform the task without assistance, 12% required some assistance or were unable to complete the task. Of those who said they could perform the task with a cane or walker, 48% required either assistance or were unable to perform the task. Of those who said they could perform the task with assistance, 24% were unable to perform the task even with assistance. In this sample of older adults receiving care in the ED, the accuracy of their self-reported ability to perform a simple mobility task was poor, particularly for those who reported some need for assistance. For older adults being considered for discharge who report a need

  15. How checking breeds doubt: reduced performance in a simple working memory task.

    Science.gov (United States)

    Harkin, Ben; Kessler, Klaus

    2009-06-01

    A paradox of memory research is that repeated checking results in a decrease in memory certainty, memory vividness and confidence [van den Hout, M. A., & Kindt, M. (2003a). Phenomenological validity of an OCD-memory model and the remember/know distinction. Behaviour Research and Therapy, 41, 369-378; van den Hout, M. A., & Kindt, M. (2003b). Repeated checking causes memory distrust. Behaviour Research and Therapy, 41, 301-316]. Although these findings have been mainly attributed to changes in episodic long-term memory, it has been suggested [Shimamura, A. P. (2000). Toward a cognitive neuroscience of metacognition. Consciousness and Cognition, 9, 313-323] that representations in working memory could already suffer from detrimental checking. In two experiments we set out to test this hypothesis by employing a delayed-match-to-sample working memory task. Letters had to be remembered in their correct locations, a task that was designed to engage the episodic short-term buffer of working memory [Baddeley, A. D. (2000). The episodic buffer: a new component in working memory? Trends in Cognitive Sciences, 4, 417-423]. Of most importance, we introduced an intermediate distractor question that was prone to induce frustrating and unnecessary checking on trials where no correct answer was possible. Reaction times and confidence ratings on the actual memory test of these trials confirmed the success of this manipulation. Most importantly, high checkers [cf. VOCI; Thordarson, D. S., Radomsky, A. S., Rachman, S., Shafran, R, Sawchuk, C. N., & Hakstian, A. R. (2004). The Vancouver obsessional compulsive inventory (VOCI). Behaviour Research and Therapy, 42(11), 1289-1314] were less accurate than low checkers when frustrating checking was induced, especially if the experimental context actually emphasized the irrelevance of the misleading question. The clinical relevance of this result was substantiated by means of an extreme groups comparison across the two studies. The findings

  16. A simple calculation algorithm to separate high-resolution CH4 flux measurements into ebullition and diffusion-derived components

    Science.gov (United States)

    Hoffmann, Mathias; Schulz-Hanke, Maximilian; Garcia Alba, Joana; Jurisch, Nicole; Hagemann, Ulrike; Sachs, Torsten; Sommer, Michael; Augustin, Jürgen

    2016-04-01

    Processes driving methane (CH4) emissions in wetland ecosystems are highly complex. Especially, the separation of CH4 emissions into ebullition and diffusion derived flux components, a perquisite for the mechanistic process understanding and identification of potential environmental driver is rather challenging. We present a simple calculation algorithm, based on an adaptive R-script, which separates open-water, closed chamber CH4 flux measurements into diffusion- and ebullition-derived components. Hence, flux component specific dynamics are revealed and potential environmental driver identified. Flux separation is based on a statistical approach, using ebullition related sudden concentration changes obtained during high resolution CH4 concentration measurements. By applying the lower and upper quartile ± the interquartile range (IQR) as a variable threshold, diffusion dominated periods of the flux measurement are filtered. Subsequently, flux calculation and separation is performed. The algorithm was verified in a laboratory experiment and tested under field conditions, using flux measurement data (July to September 2013) from a flooded, former fen grassland site. Erratic ebullition events contributed 46% to total CH4 emissions, which is comparable to values reported by literature. Additionally, a shift in the diurnal trend of diffusive fluxes throughout the measurement period, driven by the water temperature gradient, was revealed.

  17. A simple rainfall-runoff model for the single and long term hydrological performance of green roofs

    DEFF Research Database (Denmark)

    Locatelli, Luca; Mark, Ole; Mikkelsen, Peter Steen

    Green roofs are being widely implemented for storm water control and runoff reduction. There is need for incorporating green roofs into urban drainage models in order to evaluate their impact. These models must have low computational costs and fine time resolution. This paper aims to develop...... a model of green roof hydrological performance. A simple conceptual model for the long term and single event hydrological performance of green roofs, shows to be capable of reproducing observed runoff measurements. The model has surface and subsurface storage components representing the overall retention...... capacity of the green roof. The runoff from the system is described by the non-linear reservoir method and the storage capacity of the green roof is continuously re-established by evapotranspiration. Runoff data from a green roof in Denmark are collected and used for parameter calibration....

  18. Photosynthesis in Chromera velia represents a simple system with high efficiency.

    Directory of Open Access Journals (Sweden)

    Antonietta Quigg

    Full Text Available Chromera velia (Alveolata is a close relative to apicomplexan parasites with a functional photosynthetic plastid. Even though C. velia has a primitive complement of pigments (lacks chlorophyll c and uses an ancient type II form of RuBISCO, we found that its photosynthesis is very efficient with the ability to acclimate to a wide range of irradiances. C. velia maintain similar maximal photosynthetic rates when grown under continual light-limited (low light or light-saturated (high light conditions. This flexible acclimation to continuous light is provided by an increase of the chlorophyll content and photosystem II connectivity under light limited conditions and by an increase in the content of protective carotenoids together with stimulation of effective non-photochemical quenching under high light. C. velia is able to significantly increase photosynthetic rates when grown under a light-dark cycle with sinusoidal changes in light intensity. Photosynthetic activities were nonlinearly related to light intensity, with maximum performance measured at mid-morning. C. velia efficiently acclimates to changing irradiance by stimulation of photorespiration and non-photochemical quenching, thus avoiding any measurable photoinhibition. We suggest that the very high CO(2 assimilation rates under sinusoidal light regime are allowed by activation of the oxygen consuming process (possibly chlororespiration that maintains high efficiency of RuBISCO (type II. Despite the overall simplicity of the C. velia photosynthetic system, it operates with great efficiency.

  19. A simple interpolation for high and low momentum transfers in QCD

    International Nuclear Information System (INIS)

    Mignaco, J.A.; Roditi, I.

    1982-01-01

    It is shown that a simple rational approximation for the function β(g) of the renormalization group provides a useful expansion parameter for the perturbative regime in QCD and, simultaneously, allows for confinement the functional integral approximation to this problem. (Author) [pt

  20. Examining the Simple View of Reading Model for United States High School Spanish Students

    Science.gov (United States)

    Sparks, Richard; Patton, Jon

    2016-01-01

    The Simple View of Reading (SVR) model, which posits that reading comprehension is the product of word decoding and language comprehension that make independent contributions to reading skill, has been found to explain the acquisition of first language (L1) reading and second language (L2) reading in young English language learners (ELLs).…

  1. Observation of lens aberrations for high resolution electron microscopy II: Simple expressions for optimal estimates

    Energy Technology Data Exchange (ETDEWEB)

    Saxton, W. Owen, E-mail: wos1@cam.ac.uk

    2015-04-15

    This paper lists simple closed-form expressions estimating aberration coefficients (defocus, astigmatism, three-fold astigmatism, coma / misalignment, spherical aberration) on the basis of image shift or diffractogram shape measurements as a function of injected beam tilt. Simple estimators are given for a large number of injected tilt configurations, optimal in the sense of least-squares fitting of all the measurements, and so better than most reported previously. Standard errors are given for most, allowing different approaches to be compared. Special attention is given to the measurement of the spherical aberration, for which several simple procedures are given, and the effect of foreknowledge of this on other aberration estimates is noted. Details and optimal expressions are also given for a new and simple method of analysis, requiring measurements of the diffractogram mirror axis direction only, which are simpler to make than the focus and astigmatism measurements otherwise required. - Highlights: • Optimal estimators for CTEM lens aberrations are more accurate and/or use fewer observations. • Estimators have been found for defocus, astigmatism, three-fold astigmatism, coma and spherical aberration. • Estimators have been found relying on diffractogram shape, image shift and diffractogram orientation only, for a variety of beam tilts. • The standard error for each estimator has been found.

  2. Strategy Guideline: Partnering for High Performance Homes

    Energy Technology Data Exchange (ETDEWEB)

    Prahl, D.

    2013-01-01

    High performance houses require a high degree of coordination and have significant interdependencies between various systems in order to perform properly, meet customer expectations, and minimize risks for the builder. Responsibility for the key performance attributes is shared across the project team and can be well coordinated through advanced partnering strategies. For high performance homes, traditional partnerships need to be matured to the next level and be expanded to all members of the project team including trades, suppliers, manufacturers, HERS raters, designers, architects, and building officials as appropriate. In an environment where the builder is the only source of communication between trades and consultants and where relationships are, in general, adversarial as opposed to cooperative, the chances of any one building system to fail are greater. Furthermore, it is much harder for the builder to identify and capitalize on synergistic opportunities. Partnering can help bridge the cross-functional aspects of the systems approach and achieve performance-based criteria. Critical success factors for partnering include support from top management, mutual trust, effective and open communication, effective coordination around common goals, team building, appropriate use of an outside facilitator, a partnering charter progress toward common goals, an effective problem-solving process, long-term commitment, continuous improvement, and a positive experience for all involved.

  3. Quantum Accelerators for High-performance Computing Systems

    Energy Technology Data Exchange (ETDEWEB)

    Humble, Travis S. [ORNL; Britt, Keith A. [ORNL; Mohiyaddin, Fahd A. [ORNL

    2017-11-01

    We define some of the programming and system-level challenges facing the application of quantum processing to high-performance computing. Alongside barriers to physical integration, prominent differences in the execution of quantum and conventional programs challenges the intersection of these computational models. Following a brief overview of the state of the art, we discuss recent advances in programming and execution models for hybrid quantum-classical computing. We discuss a novel quantum-accelerator framework that uses specialized kernels to offload select workloads while integrating with existing computing infrastructure. We elaborate on the role of the host operating system to manage these unique accelerator resources, the prospects for deploying quantum modules, and the requirements placed on the language hierarchy connecting these different system components. We draw on recent advances in the modeling and simulation of quantum computing systems with the development of architectures for hybrid high-performance computing systems and the realization of software stacks for controlling quantum devices. Finally, we present simulation results that describe the expected system-level behavior of high-performance computing systems composed from compute nodes with quantum processing units. We describe performance for these hybrid systems in terms of time-to-solution, accuracy, and energy consumption, and we use simple application examples to estimate the performance advantage of quantum acceleration.

  4. Long-term bridge performance high priority bridge performance issues.

    Science.gov (United States)

    2014-10-01

    Bridge performance is a multifaceted issue involving performance of materials and protective systems, : performance of individual components of the bridge, and performance of the structural system as a whole. The : Long-Term Bridge Performance (LTBP)...

  5. An Introduction to High Performance Fortran

    Directory of Open Access Journals (Sweden)

    John Merlin

    1995-01-01

    Full Text Available High Performance Fortran (HPF is an informal standard for extensions to Fortran 90 to assist its implementation on parallel architectures, particularly for data-parallel computation. Among other things, it includes directives for specifying data distribution across multiple memories, and concurrent execution features. This article provides a tutorial introduction to the main features of HPF.

  6. High performance computing on vector systems

    CERN Document Server

    Roller, Sabine

    2008-01-01

    Presents the developments in high-performance computing and simulation on modern supercomputer architectures. This book covers trends in hardware and software development in general and specifically the vector-based systems and heterogeneous architectures. It presents innovative fields like coupled multi-physics or multi-scale simulations.

  7. High Performance Electronics on Flexible Silicon

    KAUST Repository

    Sevilla, Galo T.

    2016-09-01

    Over the last few years, flexible electronic systems have gained increased attention from researchers around the world because of their potential to create new applications such as flexible displays, flexible energy harvesters, artificial skin, and health monitoring systems that cannot be integrated with conventional wafer based complementary metal oxide semiconductor processes. Most of the current efforts to create flexible high performance devices are based on the use of organic semiconductors. However, inherent material\\'s limitations make them unsuitable for big data processing and high speed communications. The objective of my doctoral dissertation is to develop integration processes that allow the transformation of rigid high performance electronics into flexible ones while maintaining their performance and cost. In this work, two different techniques to transform inorganic complementary metal-oxide-semiconductor electronics into flexible ones have been developed using industry compatible processes. Furthermore, these techniques were used to realize flexible discrete devices and circuits which include metal-oxide-semiconductor field-effect-transistors, the first demonstration of flexible Fin-field-effect-transistors, and metal-oxide-semiconductors-based circuits. Finally, this thesis presents a new technique to package, integrate, and interconnect flexible high performance electronics using low cost additive manufacturing techniques such as 3D printing and inkjet printing. This thesis contains in depth studies on electrical, mechanical, and thermal properties of the fabricated devices.

  8. Debugging a high performance computing program

    Science.gov (United States)

    Gooding, Thomas M.

    2013-08-20

    Methods, apparatus, and computer program products are disclosed for debugging a high performance computing program by gathering lists of addresses of calling instructions for a plurality of threads of execution of the program, assigning the threads to groups in dependence upon the addresses, and displaying the groups to identify defective threads.

  9. Technology Leadership in Malaysia's High Performance School

    Science.gov (United States)

    Yieng, Wong Ai; Daud, Khadijah Binti

    2017-01-01

    Headmaster as leader of the school also plays a role as a technology leader. This applies to the high performance schools (HPS) headmaster as well. The HPS excel in all aspects of education. In this study, researcher is interested in examining the role of the headmaster as a technology leader through interviews with three headmasters of high…

  10. Toward High Performance in Industrial Refrigeration Systems

    DEFF Research Database (Denmark)

    Thybo, C.; Izadi-Zamanabadi, Roozbeh; Niemann, H.

    2002-01-01

    Achieving high performance in complex industrial systems requires information manipulation at different system levels. The paper shows how different models of same subsystems, but using different quality of information/data, are used for fault diagnosis as well as robust control design...

  11. Towards high performance in industrial refrigeration systems

    DEFF Research Database (Denmark)

    Thybo, C.; Izadi-Zamanabadi, R.; Niemann, Hans Henrik

    2002-01-01

    Achieving high performance in complex industrial systems requires information manipulation at different system levels. The paper shows how different models of same subsystems, but using different quality of information/data, are used for fault diagnosis as well as robust control design...

  12. Validated high performance liquid chromatographic (HPLC) method ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-02-22

    Feb 22, 2010 ... specific and accurate high performance liquid chromatographic method for determination of ZER in micro-volumes ... tional medicine as a cure for swelling, sores, loss of appetite and ... Receptor Activator for Nuclear Factor κ B Ligand .... The effect of ... be suitable for preclinical pharmacokinetic studies. The.

  13. Integrated plasma control for high performance tokamaks

    International Nuclear Information System (INIS)

    Humphreys, D.A.; Deranian, R.D.; Ferron, J.R.; Johnson, R.D.; LaHaye, R.J.; Leuer, J.A.; Penaflor, B.G.; Walker, M.L.; Welander, A.S.; Jayakumar, R.J.; Makowski, M.A.; Khayrutdinov, R.R.

    2005-01-01

    Sustaining high performance in a tokamak requires controlling many equilibrium shape and profile characteristics simultaneously with high accuracy and reliability, while suppressing a variety of MHD instabilities. Integrated plasma control, the process of designing high-performance tokamak controllers based on validated system response models and confirming their performance in detailed simulations, provides a systematic method for achieving and ensuring good control performance. For present-day devices, this approach can greatly reduce the need for machine time traditionally dedicated to control optimization, and can allow determination of high-reliability controllers prior to ever producing the target equilibrium experimentally. A full set of tools needed for this approach has recently been completed and applied to present-day devices including DIII-D, NSTX and MAST. This approach has proven essential in the design of several next-generation devices including KSTAR, EAST, JT-60SC, and ITER. We describe the method, results of design and simulation tool development, and recent research producing novel approaches to equilibrium and MHD control in DIII-D. (author)

  14. Project materials [Commercial High Performance Buildings Project

    Energy Technology Data Exchange (ETDEWEB)

    None

    2001-01-01

    The Consortium for High Performance Buildings (ChiPB) is an outgrowth of DOE'S Commercial Whole Buildings Roadmapping initiatives. It is a team-driven public/private partnership that seeks to enable and demonstrate the benefit of buildings that are designed, built and operated to be energy efficient, environmentally sustainable, superior quality, and cost effective.

  15. High performance structural ceramics for nuclear industry

    International Nuclear Information System (INIS)

    Pujari, Vimal K.; Faker, Paul

    2006-01-01

    A family of Saint-Gobain structural ceramic materials and products produced by its High performance Refractory Division is described. Over the last fifty years or so, Saint-Gobain has been a leader in developing non oxide ceramic based novel materials, processes and products for application in Nuclear, Chemical, Automotive, Defense and Mining industries

  16. A new high performance current transducer

    International Nuclear Information System (INIS)

    Tang Lijun; Lu Songlin; Li Deming

    2003-01-01

    A DC-100 kHz current transducer is developed using a new technique on zero-flux detecting principle. It was shown that the new current transducer is of high performance, its magnetic core need not be selected very stringently, and it is easy to manufacture

  17. Friction Stir Additive Manufacturing: Route to High Structural Performance

    Science.gov (United States)

    Palanivel, S.; Sidhar, H.; Mishra, R. S.

    2015-03-01

    Aerospace and automotive industries provide the next big opportunities for additive manufacturing. Currently, the additive industry is confronted with four major challenges that have been identified in this article. These challenges need to be addressed for the additive technologies to march into new frontiers and create additional markets. Specific potential success in the transportation sectors is dependent on the ability to manufacture complicated structures with high performance. Most of the techniques used for metal-based additive manufacturing are fusion based because of their ability to fulfill the computer-aided design to component vision. Although these techniques aid in fabrication of complex shapes, achieving high structural performance is a key problem due to the liquid-solid phase transformation. In this article, friction stir additive manufacturing (FSAM) is shown as a potential solid-state process for attaining high-performance lightweight alloys for simpler geometrical applications. To illustrate FSAM as a high-performance route, manufactured builds of Mg-4Y-3Nd and AA5083 are shown as examples. In the Mg-based alloy, an average hardness of 120 HV was achieved in the built structure and was significantly higher than that of the base material (97 HV). Similarly for the Al-based alloy, compared with the base hardness of 88 HV, the average built hardness was 104 HV. A potential application of FSAM is illustrated by taking an example of a simple stiffener assembly.

  18. Strategy Guideline. High Performance Residential Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Holton, J. [IBACOS, Inc., Pittsburgh, PA (United States)

    2012-02-01

    This report has been developed to provide a tool for the understanding and application of high performance lighting in the home. The strategies featured in this guide are drawn from recent advances in commercial lighting for application to typical spaces found in residential buildings. This guide offers strategies to greatly reduce lighting energy use through the application of high quality fluorescent and light emitting diode (LED) technologies. It is important to note that these strategies not only save energy in the home but also serve to satisfy the homeowner’s expectations for high quality lighting.

  19. Architecting Web Sites for High Performance

    Directory of Open Access Journals (Sweden)

    Arun Iyengar

    2002-01-01

    Full Text Available Web site applications are some of the most challenging high-performance applications currently being developed and deployed. The challenges emerge from the specific combination of high variability in workload characteristics and of high performance demands regarding the service level, scalability, availability, and costs. In recent years, a large body of research has addressed the Web site application domain, and a host of innovative software and hardware solutions have been proposed and deployed. This paper is an overview of recent solutions concerning the architectures and the software infrastructures used in building Web site applications. The presentation emphasizes three of the main functions in a complex Web site: the processing of client requests, the control of service levels, and the interaction with remote network caches.

  20. High performance anode for advanced Li batteries

    Energy Technology Data Exchange (ETDEWEB)

    Lake, Carla [Applied Sciences, Inc., Cedarville, OH (United States)

    2015-11-02

    The overall objective of this Phase I SBIR effort was to advance the manufacturing technology for ASI’s Si-CNF high-performance anode by creating a framework for large volume production and utilization of low-cost Si-coated carbon nanofibers (Si-CNF) for the battery industry. This project explores the use of nano-structured silicon which is deposited on a nano-scale carbon filament to achieve the benefits of high cycle life and high charge capacity without the consequent fading of, or failure in the capacity resulting from stress-induced fracturing of the Si particles and de-coupling from the electrode. ASI’s patented coating process distinguishes itself from others, in that it is highly reproducible, readily scalable and results in a Si-CNF composite structure containing 25-30% silicon, with a compositionally graded interface at the Si-CNF interface that significantly improve cycling stability and enhances adhesion of silicon to the carbon fiber support. In Phase I, the team demonstrated the production of the Si-CNF anode material can successfully be transitioned from a static bench-scale reactor into a fluidized bed reactor. In addition, ASI made significant progress in the development of low cost, quick testing methods which can be performed on silicon coated CNFs as a means of quality control. To date, weight change, density, and cycling performance were the key metrics used to validate the high performance anode material. Under this effort, ASI made strides to establish a quality control protocol for the large volume production of Si-CNFs and has identified several key technical thrusts for future work. Using the results of this Phase I effort as a foundation, ASI has defined a path forward to commercialize and deliver high volume and low-cost production of SI-CNF material for anodes in Li-ion batteries.

  1. NINJA: Java for High Performance Numerical Computing

    Directory of Open Access Journals (Sweden)

    José E. Moreira

    2002-01-01

    Full Text Available When Java was first introduced, there was a perception that its many benefits came at a significant performance cost. In the particularly performance-sensitive field of numerical computing, initial measurements indicated a hundred-fold performance disadvantage between Java and more established languages such as Fortran and C. Although much progress has been made, and Java now can be competitive with C/C++ in many important situations, significant performance challenges remain. Existing Java virtual machines are not yet capable of performing the advanced loop transformations and automatic parallelization that are now common in state-of-the-art Fortran compilers. Java also has difficulties in implementing complex arithmetic efficiently. These performance deficiencies can be attacked with a combination of class libraries (packages, in Java that implement truly multidimensional arrays and complex numbers, and new compiler techniques that exploit the properties of these class libraries to enable other, more conventional, optimizations. Two compiler techniques, versioning and semantic expansion, can be leveraged to allow fully automatic optimization and parallelization of Java code. Our measurements with the NINJA prototype Java environment show that Java can be competitive in performance with highly optimized and tuned Fortran code.

  2. Presentation and verification of a simple mathematical model foridentification of the areas behind noise barrierwith the highest performance

    Directory of Open Access Journals (Sweden)

    M. Monazzam

    2009-07-01

    Full Text Available Background and aims   Traffic noise barriers are the most important measure to control the environmental noise pollution. Diffraction from top edge of noise barriers is the most important path of indirect sound wave moves towards receiver.Therefore, most studies are focused on  improvement of this kind.   Methods   T-shape profile barriers are one of the most successful barrier among many different profiles. In this investigation the theory of destructive effect of diffracted waves from real edge of barrier and the wave diffracted from image of the barrier with phase difference of radians is used. Firstly a simple mathematical representation of the zones behind rigid and absorbent T- shape barriers with the highest insertion loss using the destructive effect of indirect path via barrier  image is introduced and then two different profile reflective and absorption barrier is used for  verification of the introduced model   Results   The results are then compared with the results of a verified two dimensional boundary element method at 1/3 octave band frequencies and in a wide field behind those barriers. Avery good agreement between the results has been achieved. In this method effective height is used for any different profile barriers.   Conclusion   The introduced model is very simple, flexible and fast and could be used for choosing the best location of profile rigid and absorptive barriers to achieve the highest  performance.  

  3. Sintered pellets: A simple and cost effective method to predict the performance of GGAG:Ce single crystals

    International Nuclear Information System (INIS)

    Meng, Fang; Koschan, Merry; Melcher, Charles L.; Cohen, Peter

    2015-01-01

    Highlights: • Sintered pellets were firstly used to predict the performance of single crystals. • Similar properties between sintered pellets and single crystals were investigated. • B and Ba increase luminescence intensity in pellets and light yield in crystals. • Ca shortens photoluminescence decay in pellets and scintillation decay in crystals. - Abstract: Polycrystalline Gd 3 Ga 3 Al 2 O 12 :Ce (GGAG:Ce) pellets with various codopants were prepared via solid-state synthesis and characterized by X-ray diffraction, radioluminescence (RL), photoluminescence (PL), reflectivity and PL decay measurements. GGAG:Ce pellets codoped with B and Ba were found to have higher RL intensity than pellets with other codopants, while Ca codoping improved the decay time but reduced the RL intensity. These results were strongly correlated with the performance of these codopants in GGAG:Ce single crystals. The light yield of the single crystals codoped with B or Ba was ∼15% higher than the light yield of the GGAG:Ce crystal without codoping, while Ca codoping in single crystals resulted in lower light yield but shorter scintillation decay time (43 ns vs. 56 ns). The consistent performance of these codopants in both matrix forms indicates that sintering pellets may be used as a simple cost effective technique to evaluate compositions for likely single crystal scintillator performance

  4. Profitability of simple stationary technical trading rules with high-frequency data of Chinese Index Futures

    Science.gov (United States)

    Chen, Jing-Chao; Zhou, Yu; Wang, Xi

    2018-02-01

    Technical trading rules have been widely used by practitioners in financial markets for a long time. The profitability remains controversial and few consider the stationarity of technical indicators used in trading rules. We convert MA, KDJ and Bollinger bands into stationary processes and investigate the profitability of these trading rules by using 3 high-frequency data(15s,30s and 60s) of CSI300 Stock Index Futures from January 4th 2012 to December 31st 2016. Several performance and risk measures are adopted to assess the practical value of all trading rules directly while ADF-test is used to verify the stationarity and SPA test to check whether trading rules perform well due to intrinsic superiority or pure luck. The results show that there are several significant combinations of parameters for each indicator when transaction costs are not taken into consideration. Once transaction costs are included, trading profits will be eliminated completely. We also propose a method to reduce the risk of technical trading rules.

  5. Development of high performance cladding materials

    International Nuclear Information System (INIS)

    Park, Jeong Yong; Jeong, Y. H.; Park, S. Y.

    2010-04-01

    The irradiation test for HANA claddings conducted and a series of evaluation for next-HANA claddings as well as their in-pile and out-of pile performances tests were also carried out at Halden research reactor. The 6th irradiation test have been completed successfully in Halden research reactor. As a result, HANA claddings showed high performance, such as corrosion resistance increased by 40% compared to Zircaloy-4. The high performance of HANA claddings in Halden test has enabled lead test rod program as the first step of the commercialization of HANA claddings. DB has been established for thermal and LOCA-related properties. It was confirmed from the thermal shock test that the integrity of HANA claddings was maintained in more expanded region than the criteria regulated by NRC. The manufacturing process of strips was established in order to apply HANA alloys, which were originally developed for the claddings, to the spacer grids. 250 kinds of model alloys for the next-generation claddings were designed and manufactured over 4 times and used to select the preliminary candidate alloys for the next-generation claddings. The selected candidate alloys showed 50% better corrosion resistance and 20% improved high temperature oxidation resistance compared to the foreign advanced claddings. We established the manufacturing condition controlling the performance of the dual-cooled claddings by changing the reduction rate in the cold working steps

  6. A Linux Workstation for High Performance Graphics

    Science.gov (United States)

    Geist, Robert; Westall, James

    2000-01-01

    The primary goal of this effort was to provide a low-cost method of obtaining high-performance 3-D graphics using an industry standard library (OpenGL) on PC class computers. Previously, users interested in doing substantial visualization or graphical manipulation were constrained to using specialized, custom hardware most often found in computers from Silicon Graphics (SGI). We provided an alternative to expensive SGI hardware by taking advantage of third-party, 3-D graphics accelerators that have now become available at very affordable prices. To make use of this hardware our goal was to provide a free, redistributable, and fully-compatible OpenGL work-alike library so that existing bodies of code could simply be recompiled. for PC class machines running a free version of Unix. This should allow substantial cost savings while greatly expanding the population of people with access to a serious graphics development and viewing environment. This should offer a means for NASA to provide a spectrum of graphics performance to its scientists, supplying high-end specialized SGI hardware for high-performance visualization while fulfilling the requirements of medium and lower performance applications with generic, off-the-shelf components and still maintaining compatibility between the two.

  7. The path toward HEP High Performance Computing

    CERN Document Server

    Apostolakis, John; Carminati, Federico; Gheata, Andrei; Wenzel, Sandro

    2014-01-01

    High Energy Physics code has been known for making poor use of high performance computing architectures. Efforts in optimising HEP code on vector and RISC architectures have yield limited results and recent studies have shown that, on modern architectures, it achieves a performance between 10% and 50% of the peak one. Although several successful attempts have been made to port selected codes on GPUs, no major HEP code suite has a 'High Performance' implementation. With LHC undergoing a major upgrade and a number of challenging experiments on the drawing board, HEP cannot any longer neglect the less-than-optimal performance of its code and it has to try making the best usage of the hardware. This activity is one of the foci of the SFT group at CERN, which hosts, among others, the Root and Geant4 project. The activity of the experiments is shared and coordinated via a Concurrency Forum, where the experience in optimising HEP code is presented and discussed. Another activity is the Geant-V project, centred on th...

  8. High Performance Commercial Fenestration Framing Systems

    Energy Technology Data Exchange (ETDEWEB)

    Mike Manteghi; Sneh Kumar; Joshua Early; Bhaskar Adusumalli

    2010-01-31

    A major objective of the U.S. Department of Energy is to have a zero energy commercial building by the year 2025. Windows have a major influence on the energy performance of the building envelope as they control over 55% of building energy load, and represent one important area where technologies can be developed to save energy. Aluminum framing systems are used in over 80% of commercial fenestration products (i.e. windows, curtain walls, store fronts, etc.). Aluminum framing systems are often required in commercial buildings because of their inherent good structural properties and long service life, which is required from commercial and architectural frames. At the same time, they are lightweight and durable, requiring very little maintenance, and offer design flexibility. An additional benefit of aluminum framing systems is their relatively low cost and easy manufacturability. Aluminum, being an easily recyclable material, also offers sustainable features. However, from energy efficiency point of view, aluminum frames have lower thermal performance due to the very high thermal conductivity of aluminum. Fenestration systems constructed of aluminum alloys therefore have lower performance in terms of being effective barrier to energy transfer (heat loss or gain). Despite the lower energy performance, aluminum is the choice material for commercial framing systems and dominates the commercial/architectural fenestration market because of the reasons mentioned above. In addition, there is no other cost effective and energy efficient replacement material available to take place of aluminum in the commercial/architectural market. Hence it is imperative to improve the performance of aluminum framing system to improve the energy performance of commercial fenestration system and in turn reduce the energy consumption of commercial building and achieve zero energy building by 2025. The objective of this project was to develop high performance, energy efficient commercial

  9. Production of ethanol at high temperatures in the fermentation of Jerusalem artichoke juice and a simple medium by Kluyveromyces marxianus

    Energy Technology Data Exchange (ETDEWEB)

    Rosa, M.F.; Correia, I.S.; Novais, J.M.

    1987-01-01

    Temperatures as high as 36 degrees C and 40 degrees C did not negatively affect the ethanol productivity of Jerusalem artichoke (J.a.) juice batch fermentation and the final concentrations of ethanol were close to those produced at lower temperatures. At higher process temperatures (36-40 degrees C), ethanol toxicity in Kluyveromyces marxianus was less important during the fermentation of J.a. juice as compared with a simple medium. In simple medium, the heat-sticking of fermentation was observed and the percentage of unfermented sugars steeply increased from 28 degrees C up to 40 degrees C. (Refs. 13).

  10. A simple dissolved metals mixing method to produce high-purity MgTiO3 nanocrystals

    International Nuclear Information System (INIS)

    Pratapa, Suminar; Baqiya, Malik A.; Istianah,; Lestari, Rina; Angela, Riyan

    2014-01-01

    A simple dissolved metals mixing method has been effectively used to produce high-purity MgTiO 3 (MT) nanocrystals. The method involves the mixing of independently dissolved magnesium and titanium metal powders in hydrochloric acid followed by calcination. The phase purity and nanocrystallinity were determined by making use of laboratory x-ray diffraction data, to which Rietveld-based analyses were performed. Results showed that the method yielded only one type magnesium titanate powders, i.e. MgTiO 3 , with no Mg 2 TiO 4 or MgTi 2 O 5 phases. The presence of residual rutile or periclase was controlled by adding excessive Mg up to 5% (mol) in the stoichiometric mixing. The method also resulted in MT nanocrystals with estimated average crystallite size of 76±2 nm after calcination at 600°C and 150±4 nm (at 800°C). A transmission electron micrograph confirmed the formation of the nanocrystallites

  11. HIGH PERFORMANCE CERIA BASED OXYGEN MEMBRANE

    DEFF Research Database (Denmark)

    2014-01-01

    The invention describes a new class of highly stable mixed conducting materials based on acceptor doped cerium oxide (CeO2-8 ) in which the limiting electronic conductivity is significantly enhanced by co-doping with a second element or co- dopant, such as Nb, W and Zn, so that cerium and the co......-dopant have an ionic size ratio between 0.5 and 1. These materials can thereby improve the performance and extend the range of operating conditions of oxygen permeation membranes (OPM) for different high temperature membrane reactor applications. The invention also relates to the manufacturing of supported...

  12. Playa: High-Performance Programmable Linear Algebra

    Directory of Open Access Journals (Sweden)

    Victoria E. Howle

    2012-01-01

    Full Text Available This paper introduces Playa, a high-level user interface layer for composing algorithms for complex multiphysics problems out of objects from other Trilinos packages. Among other features, Playa provides very high-performance overloaded operators implemented through an expression template mechanism. In this paper, we give an overview of the central Playa objects from a user's perspective, show application to a sequence of increasingly complex solver algorithms, provide timing results for Playa's overloaded operators and other functions, and briefly survey some of the implementation issues involved.

  13. Optimizing the design of very high power, high performance converters

    International Nuclear Information System (INIS)

    Edwards, R.J.; Tiagha, E.A.; Ganetis, G.; Nawrocky, R.J.

    1980-01-01

    This paper describes how various technologies are used to achieve the desired performance in a high current magnet power converter system. It is hoped that the discussions of the design approaches taken will be applicable to other power supply systems where stringent requirements in stability, accuracy and reliability must be met

  14. Robust High Performance Aquaporin based Biomimetic Membranes

    DEFF Research Database (Denmark)

    Helix Nielsen, Claus; Zhao, Yichun; Qiu, C.

    2013-01-01

    on top of a support membrane. Control membranes, either without aquaporins or with the inactive AqpZ R189A mutant aquaporin served as controls. The separation performance of the membranes was evaluated by cross-flow forward osmosis (FO) and reverse osmosis (RO) tests. In RO the ABM achieved a water......Aquaporins are water channel proteins with high water permeability and solute rejection, which makes them promising for preparing high-performance biomimetic membranes. Despite the growing interest in aquaporin-based biomimetic membranes (ABMs), it is challenging to produce robust and defect...... permeability of ~ 4 L/(m2 h bar) with a NaCl rejection > 97% at an applied hydraulic pressure of 5 bar. The water permeability was ~40% higher compared to a commercial brackish water RO membrane (BW30) and an order of magnitude higher compared to a seawater RO membrane (SW30HR). In FO, the ABMs had > 90...

  15. Evaluation of high-performance computing software

    Energy Technology Data Exchange (ETDEWEB)

    Browne, S.; Dongarra, J. [Univ. of Tennessee, Knoxville, TN (United States); Rowan, T. [Oak Ridge National Lab., TN (United States)

    1996-12-31

    The absence of unbiased and up to date comparative evaluations of high-performance computing software complicates a user`s search for the appropriate software package. The National HPCC Software Exchange (NHSE) is attacking this problem using an approach that includes independent evaluations of software, incorporation of author and user feedback into the evaluations, and Web access to the evaluations. We are applying this approach to the Parallel Tools Library (PTLIB), a new software repository for parallel systems software and tools, and HPC-Netlib, a high performance branch of the Netlib mathematical software repository. Updating the evaluations with feed-back and making it available via the Web helps ensure accuracy and timeliness, and using independent reviewers produces unbiased comparative evaluations difficult to find elsewhere.

  16. High performance cloud auditing and applications

    CERN Document Server

    Choi, Baek-Young; Song, Sejun

    2014-01-01

    This book mainly focuses on cloud security and high performance computing for cloud auditing. The book discusses emerging challenges and techniques developed for high performance semantic cloud auditing, and presents the state of the art in cloud auditing, computing and security techniques with focus on technical aspects and feasibility of auditing issues in federated cloud computing environments.   In summer 2011, the United States Air Force Research Laboratory (AFRL) CyberBAT Cloud Security and Auditing Team initiated the exploration of the cloud security challenges and future cloud auditing research directions that are covered in this book. This work was supported by the United States government funds from the Air Force Office of Scientific Research (AFOSR), the AFOSR Summer Faculty Fellowship Program (SFFP), the Air Force Research Laboratory (AFRL) Visiting Faculty Research Program (VFRP), the National Science Foundation (NSF) and the National Institute of Health (NIH). All chapters were partially suppor...

  17. Monitoring SLAC High Performance UNIX Computing Systems

    International Nuclear Information System (INIS)

    Lettsome, Annette K.

    2005-01-01

    Knowledge of the effectiveness and efficiency of computers is important when working with high performance systems. The monitoring of such systems is advantageous in order to foresee possible misfortunes or system failures. Ganglia is a software system designed for high performance computing systems to retrieve specific monitoring information. An alternative storage facility for Ganglia's collected data is needed since its default storage system, the round-robin database (RRD), struggles with data integrity. The creation of a script-driven MySQL database solves this dilemma. This paper describes the process took in the creation and implementation of the MySQL database for use by Ganglia. Comparisons between data storage by both databases are made using gnuplot and Ganglia's real-time graphical user interface

  18. High performance parallel computers for science

    International Nuclear Information System (INIS)

    Nash, T.; Areti, H.; Atac, R.; Biel, J.; Cook, A.; Deppe, J.; Edel, M.; Fischler, M.; Gaines, I.; Hance, R.

    1989-01-01

    This paper reports that Fermilab's Advanced Computer Program (ACP) has been developing cost effective, yet practical, parallel computers for high energy physics since 1984. The ACP's latest developments are proceeding in two directions. A Second Generation ACP Multiprocessor System for experiments will include $3500 RISC processors each with performance over 15 VAX MIPS. To support such high performance, the new system allows parallel I/O, parallel interprocess communication, and parallel host processes. The ACP Multi-Array Processor, has been developed for theoretical physics. Each $4000 node is a FORTRAN or C programmable pipelined 20 Mflops (peak), 10 MByte single board computer. These are plugged into a 16 port crossbar switch crate which handles both inter and intra crate communication. The crates are connected in a hypercube. Site oriented applications like lattice gauge theory are supported by system software called CANOPY, which makes the hardware virtually transparent to users. A 256 node, 5 GFlop, system is under construction

  19. Toward a theory of high performance.

    Science.gov (United States)

    Kirby, Julia

    2005-01-01

    What does it mean to be a high-performance company? The process of measuring relative performance across industries and eras, declaring top performers, and finding the common drivers of their success is such a difficult one that it might seem a fool's errand to attempt. In fact, no one did for the first thousand or so years of business history. The question didn't even occur to many scholars until Tom Peters and Bob Waterman released In Search of Excellence in 1982. Twenty-three years later, we've witnessed several more attempts--and, just maybe, we're getting closer to answers. In this reported piece, HBR senior editor Julia Kirby explores why it's so difficult to study high performance and how various research efforts--including those from John Kotter and Jim Heskett; Jim Collins and Jerry Porras; Bill Joyce, Nitin Nohria, and Bruce Roberson; and several others outlined in a summary chart-have attacked the problem. The challenge starts with deciding which companies to study closely. Are the stars the ones with the highest market caps, the ones with the greatest sales growth, or simply the ones that remain standing at the end of the game? (And when's the end of the game?) Each major study differs in how it defines success, which companies it therefore declares to be worthy of emulation, and the patterns of activity and attitude it finds in common among them. Yet, Kirby concludes, as each study's method incrementally solves problems others have faced, we are progressing toward a consensus theory of high performance.

  20. High-performance phase-field modeling

    KAUST Repository

    Vignal, Philippe; Sarmiento, Adel; Cortes, Adriano Mauricio; Dalcin, L.; Collier, N.; Calo, Victor M.

    2015-01-01

    and phase-field crystal equation will be presented, which corroborate the theoretical findings, and illustrate the robustness of the method. Results related to more challenging examples, namely the Navier-Stokes Cahn-Hilliard and a diusion-reaction Cahn-Hilliard system, will also be presented. The implementation was done in PetIGA and PetIGA-MF, high-performance Isogeometric Analysis frameworks [1, 3], designed to handle non-linear, time-dependent problems.

  1. AHPCRC - Army High Performance Computing Research Center

    Science.gov (United States)

    2010-01-01

    computing. Of particular interest is the ability of a distrib- uted jamming network (DJN) to jam signals in all or part of a sensor or communications net...and reasoning, assistive technologies. FRIEDRICH (FRITZ) PRINZ Finmeccanica Professor of Engineering, Robert Bosch Chair, Department of Engineering...High Performance Computing Research Center www.ahpcrc.org BARBARA BRYAN AHPCRC Research and Outreach Manager, HPTi (650) 604-3732 bbryan@hpti.com Ms

  2. Performance concerns for high duty fuel cycle

    International Nuclear Information System (INIS)

    Esposito, V.J.; Gutierrez, J.E.

    1999-01-01

    One of the goals of the nuclear industry is to achieve economic performance such that nuclear power plants are competitive in a de-regulated market. The manner in which nuclear fuel is designed and operated lies at the heart of economic viability. In this sense reliability, operating flexibility and low costs are the three major requirements of the NPP today. The translation of these three requirements to the design is part of our work. The challenge today is to produce a fuel design which will operate with long operating cycles, high discharge burnup, power up-rating and while still maintaining all design and safety margins. European Fuel Group (EFG) understands that to achieve the required performance high duty/energy fuel designs are needed. The concerns for high duty design includes, among other items, core design methods, advanced Safety Analysis methodologies, performance models, advanced material and operational strategies. The operational aspects require the trade-off and evaluation of various parameters including coolant chemistry control, material corrosion, boiling duty, boron level impacts, etc. In this environment MAEF is the design that EFG is now offering based on ZIRLO alloy and a robust skeleton. This new design is able to achieve 70 GWd/tU and Lead Test Programs are being executed to demonstrate this capability. A number of performance issues which have been a concern with current designs have been resolved such as cladding corrosion and incomplete RCCA insertion (IRI). As the core duty becomes more aggressive other new issues need to be addressed such as Axial Offset Anomaly. These new issues are being addressed by combination of the new design in concert with advanced methodologies to meet the demanding needs of NPP. The ability and strategy to meet high duty core requirements, flexibility of operation and maintain acceptable balance of all technical issues is the discussion in this paper. (authors)

  3. DURIP: High Performance Computing in Biomathematics Applications

    Science.gov (United States)

    2017-05-10

    Mathematics and Statistics (AMS) at the University of California, Santa Cruz (UCSC) to conduct research and research-related education in areas of...Computing in Biomathematics Applications Report Title The goal of this award was to enhance the capabilities of the Department of Applied Mathematics and...DURIP: High Performance Computing in Biomathematics Applications The goal of this award was to enhance the capabilities of the Department of Applied

  4. High Performance Computing Operations Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Cupps, Kimberly C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-12-19

    The High Performance Computing Operations Review (HPCOR) meeting—requested by the ASC and ASCR program headquarters at DOE—was held November 5 and 6, 2013, at the Marriott Hotel in San Francisco, CA. The purpose of the review was to discuss the processes and practices for HPC integration and its related software and facilities. Experiences and lessons learned from the most recent systems deployed were covered in order to benefit the deployment of new systems.

  5. Planning for high performance project teams

    International Nuclear Information System (INIS)

    Reed, W.; Keeney, J.; Westney, R.

    1997-01-01

    Both industry-wide research and corporate benchmarking studies confirm the significant savings in cost and time that result from early planning of a project. Amoco's Team Planning Workshop combines long-term strategic project planning and short-term tactical planning with team building to provide the basis for high performing project teams, better project planning, and effective implementation of the Amoco Common Process for managing projects

  6. Computational Biology and High Performance Computing 2000

    Energy Technology Data Exchange (ETDEWEB)

    Simon, Horst D.; Zorn, Manfred D.; Spengler, Sylvia J.; Shoichet, Brian K.; Stewart, Craig; Dubchak, Inna L.; Arkin, Adam P.

    2000-10-19

    The pace of extraordinary advances in molecular biology has accelerated in the past decade due in large part to discoveries coming from genome projects on human and model organisms. The advances in the genome project so far, happening well ahead of schedule and under budget, have exceeded any dreams by its protagonists, let alone formal expectations. Biologists expect the next phase of the genome project to be even more startling in terms of dramatic breakthroughs in our understanding of human biology, the biology of health and of disease. Only today can biologists begin to envision the necessary experimental, computational and theoretical steps necessary to exploit genome sequence information for its medical impact, its contribution to biotechnology and economic competitiveness, and its ultimate contribution to environmental quality. High performance computing has become one of the critical enabling technologies, which will help to translate this vision of future advances in biology into reality. Biologists are increasingly becoming aware of the potential of high performance computing. The goal of this tutorial is to introduce the exciting new developments in computational biology and genomics to the high performance computing community.

  7. High performance separation of lanthanides and actinides

    International Nuclear Information System (INIS)

    Sivaraman, N.; Vasudeva Rao, P.R.

    2011-01-01

    The major advantage of High Performance Liquid Chromatography (HPLC) is its ability to provide rapid and high performance separations. It is evident from Van Deemter curve for particle size versus resolution that packing materials with particle sizes less than 2 μm provide better resolution for high speed separations and resolving complex mixtures compared to 5 μm based supports. In the recent past, chromatographic support material using monolith has been studied extensively at our laboratory. Monolith column consists of single piece of porous, rigid material containing mesopores and micropores, which provide fast analyte mass transfer. Monolith support provides significantly higher separation efficiency than particle-packed columns. A clear advantage of monolith is that it could be operated at higher flow rates but with lower back pressure. Higher operating flow rate results in higher column permeability, which drastically reduces analysis time and provides high separation efficiency. The above developed fast separation methods were applied to assay the lanthanides and actinides from the dissolver solutions of nuclear reactor fuels

  8. High Performance OLED Panel and Luminaire

    Energy Technology Data Exchange (ETDEWEB)

    Spindler, Jeffrey [OLEDWorks LLC, Rochester, NY (United States)

    2017-02-20

    In this project, OLEDWorks developed and demonstrated the technology required to produce OLED lighting panels with high energy efficiency and excellent light quality. OLED panels developed in this program produce high quality warm white light with CRI greater than 85 and efficacy up to 80 lumens per watt (LPW). An OLED luminaire employing 24 of the high performance panels produces practical levels of illumination for general lighting, with a flux of over 2200 lumens at 60 LPW. This is a significant advance in the state of the art for OLED solid-state lighting (SSL), which is expected to be a complementary light source to the more advanced LED SSL technology that is rapidly replacing all other traditional forms of lighting.

  9. The path toward HEP High Performance Computing

    International Nuclear Information System (INIS)

    Apostolakis, John; Brun, René; Gheata, Andrei; Wenzel, Sandro; Carminati, Federico

    2014-01-01

    High Energy Physics code has been known for making poor use of high performance computing architectures. Efforts in optimising HEP code on vector and RISC architectures have yield limited results and recent studies have shown that, on modern architectures, it achieves a performance between 10% and 50% of the peak one. Although several successful attempts have been made to port selected codes on GPUs, no major HEP code suite has a 'High Performance' implementation. With LHC undergoing a major upgrade and a number of challenging experiments on the drawing board, HEP cannot any longer neglect the less-than-optimal performance of its code and it has to try making the best usage of the hardware. This activity is one of the foci of the SFT group at CERN, which hosts, among others, the Root and Geant4 project. The activity of the experiments is shared and coordinated via a Concurrency Forum, where the experience in optimising HEP code is presented and discussed. Another activity is the Geant-V project, centred on the development of a highperformance prototype for particle transport. Achieving a good concurrency level on the emerging parallel architectures without a complete redesign of the framework can only be done by parallelizing at event level, or with a much larger effort at track level. Apart the shareable data structures, this typically implies a multiplication factor in terms of memory consumption compared to the single threaded version, together with sub-optimal handling of event processing tails. Besides this, the low level instruction pipelining of modern processors cannot be used efficiently to speedup the program. We have implemented a framework that allows scheduling vectors of particles to an arbitrary number of computing resources in a fine grain parallel approach. The talk will review the current optimisation activities within the SFT group with a particular emphasis on the development perspectives towards a simulation framework able to profit

  10. A High Performance COTS Based Computer Architecture

    Science.gov (United States)

    Patte, Mathieu; Grimoldi, Raoul; Trautner, Roland

    2014-08-01

    Using Commercial Off The Shelf (COTS) electronic components for space applications is a long standing idea. Indeed the difference in processing performance and energy efficiency between radiation hardened components and COTS components is so important that COTS components are very attractive for use in mass and power constrained systems. However using COTS components in space is not straightforward as one must account with the effects of the space environment on the COTS components behavior. In the frame of the ESA funded activity called High Performance COTS Based Computer, Airbus Defense and Space and its subcontractor OHB CGS have developed and prototyped a versatile COTS based architecture for high performance processing. The rest of the paper is organized as follows: in a first section we will start by recapitulating the interests and constraints of using COTS components for space applications; then we will briefly describe existing fault mitigation architectures and present our solution for fault mitigation based on a component called the SmartIO; in the last part of the paper we will describe the prototyping activities executed during the HiP CBC project.

  11. Management issues for high performance storage systems

    Energy Technology Data Exchange (ETDEWEB)

    Louis, S. [Lawrence Livermore National Lab., CA (United States); Burris, R. [Oak Ridge National Lab., TN (United States)

    1995-03-01

    Managing distributed high-performance storage systems is complex and, although sharing common ground with traditional network and systems management, presents unique storage-related issues. Integration technologies and frameworks exist to help manage distributed network and system environments. Industry-driven consortia provide open forums where vendors and users cooperate to leverage solutions. But these new approaches to open management fall short addressing the needs of scalable, distributed storage. We discuss the motivation and requirements for storage system management (SSM) capabilities and describe how SSM manages distributed servers and storage resource objects in the High Performance Storage System (HPSS), a new storage facility for data-intensive applications and large-scale computing. Modem storage systems, such as HPSS, require many SSM capabilities, including server and resource configuration control, performance monitoring, quality of service, flexible policies, file migration, file repacking, accounting, and quotas. We present results of initial HPSS SSM development including design decisions and implementation trade-offs. We conclude with plans for follow-on work and provide storage-related recommendations for vendors and standards groups seeking enterprise-wide management solutions.

  12. Performance effects of nicotine during selective attention, divided attention, and simple stimulus detection: an fMRI study.

    Science.gov (United States)

    Hahn, Britta; Ross, Thomas J; Wolkenberg, Frank A; Shakleya, Diaa M; Huestis, Marilyn A; Stein, Elliot A

    2009-09-01

    Attention-enhancing effects of nicotine appear to depend on the nature of the attentional function. Underlying neuroanatomical mechanisms, too, may vary depending on the function modulated. This functional magnetic resonance imaging study recorded blood oxygen level-dependent (BOLD) activity in minimally deprived smokers during tasks of simple stimulus detection, selective attention, or divided attention after single-blind application of a transdermal nicotine (21 mg) or placebo patch. Smokers' performance in the placebo condition was unimpaired as compared with matched nonsmokers. Nicotine reduced reaction time (RT) in the stimulus detection and selective attention but not divided attention condition. Across all task conditions, nicotine reduced activation in frontal, temporal, thalamic, and visual regions and enhanced deactivation in so-called "default" regions. Thalamic effects correlated with RT reduction selectively during stimulus detection. An interaction with task condition was observed in middle and superior frontal gyri, where nicotine reduced activation only during stimulus detection. A visuomotor control experiment provided evidence against nonspecific effects of nicotine. In conclusion, although prefrontal activity partly displayed differential modulation by nicotine, most BOLD effects were identical across tasks, despite differential performance effects, suggesting that common neuronal mechanisms can selectively benefit different attentional functions. Overall, the effects of nicotine may be explained by increased functional efficiency and downregulated task-independent "default" functions.

  13. Automatic Energy Schemes for High Performance Applications

    Energy Technology Data Exchange (ETDEWEB)

    Sundriyal, Vaibhav [Iowa State Univ., Ames, IA (United States)

    2013-01-01

    Although high-performance computing traditionally focuses on the efficient execution of large-scale applications, both energy and power have become critical concerns when approaching exascale. Drastic increases in the power consumption of supercomputers affect significantly their operating costs and failure rates. In modern microprocessor architectures, equipped with dynamic voltage and frequency scaling (DVFS) and CPU clock modulation (throttling), the power consumption may be controlled in software. Additionally, network interconnect, such as Infiniband, may be exploited to maximize energy savings while the application performance loss and frequency switching overheads must be carefully balanced. This work first studies two important collective communication operations, all-to-all and allgather and proposes energy saving strategies on the per-call basis. Next, it targets point-to-point communications to group them into phases and apply frequency scaling to them to save energy by exploiting the architectural and communication stalls. Finally, it proposes an automatic runtime system which combines both collective and point-to-point communications into phases, and applies throttling to them apart from DVFS to maximize energy savings. The experimental results are presented for NAS parallel benchmark problems as well as for the realistic parallel electronic structure calculations performed by the widely used quantum chemistry package GAMESS. Close to the maximum energy savings were obtained with a substantially low performance loss on the given platform.

  14. High-performance computing in seismology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    The scientific, technical, and economic importance of the issues discussed here presents a clear agenda for future research in computational seismology. In this way these problems will drive advances in high-performance computing in the field of seismology. There is a broad community that will benefit from this work, including the petroleum industry, research geophysicists, engineers concerned with seismic hazard mitigation, and governments charged with enforcing a comprehensive test ban treaty. These advances may also lead to new applications for seismological research. The recent application of high-resolution seismic imaging of the shallow subsurface for the environmental remediation industry is an example of this activity. This report makes the following recommendations: (1) focused efforts to develop validated documented software for seismological computations should be supported, with special emphasis on scalable algorithms for parallel processors; (2) the education of seismologists in high-performance computing technologies and methodologies should be improved; (3) collaborations between seismologists and computational scientists and engineers should be increased; (4) the infrastructure for archiving, disseminating, and processing large volumes of seismological data should be improved.

  15. A high performance architecture for accelerator controls

    International Nuclear Information System (INIS)

    Allen, M.; Hunt, S.M; Lue, H.; Saltmarsh, C.G.; Parker, C.R.C.B.

    1991-01-01

    The demands placed on the Superconducting Super Collider (SSC) control system due to large distances, high bandwidth and fast response time required for operation will require a fresh approach to the data communications architecture of the accelerator. The prototype design effort aims at providing deterministic communication across the accelerator complex with a response time of < 100 ms and total bandwidth of 2 Gbits/sec. It will offer a consistent interface for a large number of equipment types, from vacuum pumps to beam position monitors, providing appropriate communications performance for each equipment type. It will consist of highly parallel links to all equipment: those with computing resources, non-intelligent direct control interfaces, and data concentrators. This system will give each piece of equipment a dedicated link of fixed bandwidth to the control system. Application programs will have access to all accelerator devices which will be memory mapped into a global virtual addressing scheme. Links to devices in the same geographical area will be multiplexed using commercial Time Division Multiplexing equipment. Low-level access will use reflective memory techniques, eliminating processing overhead and complexity of traditional data communication protocols. The use of commercial standards and equipment will enable a high performance system to be built at low cost

  16. A high performance architecture for accelerator controls

    International Nuclear Information System (INIS)

    Allen, M.; Hunt, S.M.; Lue, H.; Saltmarsh, C.G.; Parker, C.R.C.B.

    1991-03-01

    The demands placed on the Superconducting Super Collider (SSC) control system due to large distances, high bandwidth and fast response time required for operation will require a fresh approach to the data communications architecture of the accelerator. The prototype design effort aims at providing deterministic communication across the accelerator complex with a response time of <100 ms and total bandwidth of 2 Gbits/sec. It will offer a consistent interface for a large number of equipment types, from vacuum pumps to beam position monitors, providing appropriate communications performance for each equipment type. It will consist of highly parallel links to all equipments: those with computing resources, non-intelligent direct control interfaces, and data concentrators. This system will give each piece of equipment a dedicated link of fixed bandwidth to the control system. Application programs will have access to all accelerator devices which will be memory mapped into a global virtual addressing scheme. Links to devices in the same geographical area will be multiplexed using commercial Time Division Multiplexing equipment. Low-level access will use reflective memory techniques, eliminating processing overhead and complexity of traditional data communication protocols. The use of commercial standards and equipment will enable a high performance system to be built at low cost. 1 fig

  17. High performance computing in linear control

    International Nuclear Information System (INIS)

    Datta, B.N.

    1993-01-01

    Remarkable progress has been made in both theory and applications of all important areas of control. The theory is rich and very sophisticated. Some beautiful applications of control theory are presently being made in aerospace, biomedical engineering, industrial engineering, robotics, economics, power systems, etc. Unfortunately, the same assessment of progress does not hold in general for computations in control theory. Control Theory is lagging behind other areas of science and engineering in this respect. Nowadays there is a revolution going on in the world of high performance scientific computing. Many powerful computers with vector and parallel processing have been built and have been available in recent years. These supercomputers offer very high speed in computations. Highly efficient software, based on powerful algorithms, has been developed to use on these advanced computers, and has also contributed to increased performance. While workers in many areas of science and engineering have taken great advantage of these hardware and software developments, control scientists and engineers, unfortunately, have not been able to take much advantage of these developments

  18. Building Trust in High-Performing Teams

    Directory of Open Access Journals (Sweden)

    Aki Soudunsaari

    2012-06-01

    Full Text Available Facilitation of growth is more about good, trustworthy contacts than capital. Trust is a driving force for business creation, and to create a global business you need to build a team that is capable of meeting the challenge. Trust is a key factor in team building and a needed enabler for cooperation. In general, trust building is a slow process, but it can be accelerated with open interaction and good communication skills. The fast-growing and ever-changing nature of global business sets demands for cooperation and team building, especially for startup companies. Trust building needs personal knowledge and regular face-to-face interaction, but it also requires empathy, respect, and genuine listening. Trust increases communication, and rich and open communication is essential for the building of high-performing teams. Other building materials are a shared vision, clear roles and responsibilities, willingness for cooperation, and supporting and encouraging leadership. This study focuses on trust in high-performing teams. It asks whether it is possible to manage trust and which tools and operation models should be used to speed up the building of trust. In this article, preliminary results from the authors’ research are presented to highlight the importance of sharing critical information and having a high level of communication through constant interaction.

  19. Improving UV Resistance of High Performance Fibers

    Science.gov (United States)

    Hassanin, Ahmed

    High performance fibers are characterized by their superior properties compared to the traditional textile fibers. High strength fibers have high modules, high strength to weight ratio, high chemical resistance, and usually high temperature resistance. It is used in application where superior properties are needed such as bulletproof vests, ropes and cables, cut resistant products, load tendons for giant scientific balloons, fishing rods, tennis racket strings, parachute cords, adhesives and sealants, protective apparel and tire cords. Unfortunately, Ultraviolet (UV) radiation causes serious degradation to the most of high performance fibers. UV lights, either natural or artificial, cause organic compounds to decompose and degrade, because the energy of the photons of UV light is high enough to break chemical bonds causing chain scission. This work is aiming at achieving maximum protection of high performance fibers using sheathing approaches. The sheaths proposed are of lightweight to maintain the advantage of the high performance fiber that is the high strength to weight ratio. This study involves developing three different types of sheathing. The product of interest that need be protected from UV is braid from PBO. First approach is extruding a sheath from Low Density Polyethylene (LDPE) loaded with different rutile TiO2 % nanoparticles around the braid from the PBO. The results of this approach showed that LDPE sheath loaded with 10% TiO2 by weight achieved the highest protection compare to 0% and 5% TiO2. The protection here is judged by strength loss of PBO. This trend noticed in different weathering environments, where the sheathed samples were exposed to UV-VIS radiations in different weatheromter equipments as well as exposure to high altitude environment using NASA BRDL balloon. The second approach is focusing in developing a protective porous membrane from polyurethane loaded with rutile TiO2 nanoparticles. Membrane from polyurethane loaded with 4

  20. Intel Xeon Phi coprocessor high performance programming

    CERN Document Server

    Jeffers, James

    2013-01-01

    Authors Jim Jeffers and James Reinders spent two years helping educate customers about the prototype and pre-production hardware before Intel introduced the first Intel Xeon Phi coprocessor. They have distilled their own experiences coupled with insights from many expert customers, Intel Field Engineers, Application Engineers and Technical Consulting Engineers, to create this authoritative first book on the essentials of programming for this new architecture and these new products. This book is useful even before you ever touch a system with an Intel Xeon Phi coprocessor. To ensure that your applications run at maximum efficiency, the authors emphasize key techniques for programming any modern parallel computing system whether based on Intel Xeon processors, Intel Xeon Phi coprocessors, or other high performance microprocessors. Applying these techniques will generally increase your program performance on any system, and better prepare you for Intel Xeon Phi coprocessors and the Intel MIC architecture. It off...

  1. Development of high-performance blended cements

    Science.gov (United States)

    Wu, Zichao

    2000-10-01

    This thesis presents the development of high-performance blended cements from industrial by-products. To overcome the low-early strength of blended cements, several chemicals were studied as the activators for cement hydration. Sodium sulfate was discovered as the best activator. The blending proportions were optimized by Taguchi experimental design. The optimized blended cements containing up to 80% fly ash performed better than Type I cement in strength development and durability. Maintaining a constant cement content, concrete produced from the optimized blended cements had equal or higher strength and higher durability than that produced from Type I cement alone. The key for the activation mechanism was the reaction between added SO4 2- and Ca2+ dissolved from cement hydration products.

  2. URS Altiva – a new oat cultivar with high agronomic performance

    Directory of Open Access Journals (Sweden)

    Itamar C. Nava

    2016-09-01

    Full Text Available The oat cultivar URS Altiva, developed from the simple cross ‘UFRGS 995090-2 x URS 21’, and released by the Oat Breeding Program of the Federal University of Rio Grande do Sul (UFRGS in 2015, presents high grain yield, high grain quality, desirable agronomic performance, and partial resistance to crown rust.

  3. A simple and convenient set-up for high-temperature Brillouin light scattering

    International Nuclear Information System (INIS)

    Guerette, Michael; Huang Liping

    2012-01-01

    An emulated platelet geometry (or reflection-induced platelet geometry) is employed to collect photons scattered from both longitudinal and transverse acoustic waves travelling within a bulk transparent sample sitting on a reflective Pt plate. Temperature of the sample was controlled with a Linkam TS1500 optical furnace (maximum temperature of 1500 °C). This simple and convenient set-up allows a full determination of elastic constants of transparent materials in situ as a function of temperature from Brillouin light scattering. Structural information can be gained at the same time by guiding the scattered light into a Raman spectrometer using a flipping mirror or a beam splitter. We will demonstrate the applications of this set-up in transparent inorganic glasses, but it can be easily extended to any other transparent materials, either crystalline or amorphous in nature. (paper)

  4. A simple sub-nanosecond ultraviolet light pulse generator with high repetition rate and peak power.

    Science.gov (United States)

    Binh, P H; Trong, V D; Renucci, P; Marie, X

    2013-08-01

    We present a simple ultraviolet sub-nanosecond pulse generator using commercial ultraviolet light-emitting diodes with peak emission wavelengths of 290 nm, 318 nm, 338 nm, and 405 nm. The generator is based on step recovery diode, short-circuited transmission line, and current-shaping circuit. The narrowest pulses achieved have 630 ps full width at half maximum at repetition rate of 80 MHz. Optical pulse power in the range of several hundreds of microwatts depends on the applied bias voltage. The bias voltage dependences of the output optical pulse width and peak power are analysed and discussed. Compared to commercial UV sub-nanosecond generators, the proposed generator can produce much higher pulse repetition rate and peak power.

  5. Utilities for high performance dispersion model PHYSIC

    International Nuclear Information System (INIS)

    Yamazawa, Hiromi

    1992-09-01

    The description and usage of the utilities for the dispersion calculation model PHYSIC were summarized. The model was developed in the study of developing high performance SPEEDI with the purpose of introducing meteorological forecast function into the environmental emergency response system. The procedure of PHYSIC calculation consists of three steps; preparation of relevant files, creation and submission of JCL, and graphic output of results. A user can carry out the above procedure with the help of the Geographical Data Processing Utility, the Model Control Utility, and the Graphic Output Utility. (author)

  6. An integrated high performance fastbus slave interface

    International Nuclear Information System (INIS)

    Christiansen, J.; Ljuslin, C.

    1992-01-01

    A high performance Fastbus slave interface ASIC is presented. The Fastbus slave integrated circuit (FASIC) is a programmable device, enabling its direct use in many different applications. The FASIC acts as an interface between Fastbus and a 'standard' processor/memory bus. It can work stand-alone or together with a microprocessor. A set of address mapping windows can map Fastbus addresses to convenient memory addresses and at the same time act as address decoding logic. Data rates of 100 MBytes/s to Fastbus can be obtained using an internal FIFO buffer in the FASIC. (orig.)

  7. High performance visual display for HENP detectors

    CERN Document Server

    McGuigan, M; Spiletic, J; Fine, V; Nevski, P

    2001-01-01

    A high end visual display for High Energy Nuclear Physics (HENP) detectors is necessary because of the sheer size and complexity of the detector. For BNL this display will be of special interest because of STAR and ATLAS. To load, rotate, query, and debug simulation code with a modern detector simply takes too long even on a powerful work station. To visualize the HENP detectors with maximal performance we have developed software with the following characteristics. We develop a visual display of HENP detectors on BNL multiprocessor visualization server at multiple level of detail. We work with general and generic detector framework consistent with ROOT, GAUDI etc, to avoid conflicting with the many graphic development groups associated with specific detectors like STAR and ATLAS. We develop advanced OpenGL features such as transparency and polarized stereoscopy. We enable collaborative viewing of detector and events by directly running the analysis in BNL stereoscopic theatre. We construct enhanced interactiv...

  8. High-Performance Vertical Organic Electrochemical Transistors.

    Science.gov (United States)

    Donahue, Mary J; Williamson, Adam; Strakosas, Xenofon; Friedlein, Jacob T; McLeod, Robert R; Gleskova, Helena; Malliaras, George G

    2018-02-01

    Organic electrochemical transistors (OECTs) are promising transducers for biointerfacing due to their high transconductance, biocompatibility, and availability in a variety of form factors. Most OECTs reported to date, however, utilize rather large channels, limiting the transistor performance and resulting in a low transistor density. This is typically a consequence of limitations associated with traditional fabrication methods and with 2D substrates. Here, the fabrication and characterization of OECTs with vertically stacked contacts, which overcome these limitations, is reported. The resulting vertical transistors exhibit a reduced footprint, increased intrinsic transconductance of up to 57 mS, and a geometry-normalized transconductance of 814 S m -1 . The fabrication process is straightforward and compatible with sensitive organic materials, and allows exceptional control over the transistor channel length. This novel 3D fabrication method is particularly suited for applications where high density is needed, such as in implantable devices. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. A new simple and cheap, high-resolution planar optode imaging system: Application to oxgen and pH sensing

    DEFF Research Database (Denmark)

    Larsen, Morten; Borisov, Sergey M.; Gunwald, Björn

    2011-01-01

    A simple, high resolution colormetric planar optode imaging approach is presented. The approach is simple and inexpensive yet versatile, and can be used to study the two-dimensional distribution and dynamics of a range of analytes. The imaging approach utilizes the inbuilt color filter of standard...... commercial digital single lens reflex cameras to simultaneously record different colors (red, green, and blue) of luminophore emission light using only one excitation light source. Using the ratio between the intensity of the different colors recorded in a single image analyte concentrations can...... be calculated. The robustness of the approach is documented by obtaining high resolution data of O2 and pH distributions in marine sediments using easy synthesizable sensors. The sensors rely on the platinum(II)octaethylporphyrin (PtOEP) and lipophilic 8-Hydroxy-1,3,6-pyrenetrisulfonic acid trisodium (HPTS...

  10. A simple and inexpensive high resolution color ratiometric planar optode imaging approach: application to oxygen and pH sensing

    DEFF Research Database (Denmark)

    Larsen, M.; Borisov, S. M.; Grunwald, B.

    2011-01-01

    A simple, high resolution colormetric planar optode imaging approach is presented. The approach is simple and inexpensive yet versatile, and can be used to study the two-dimensional distribution and dynamics of a range of analytes. The imaging approach utilizes the inbuilt color filter of standard...... commercial digital single lens reflex cameras to simultaneously record different colors (red, green, and blue) of luminophore emission light using only one excitation light source. Using the ratio between the intensity of the different colors recorded in a single image analyte concentrations can...... be calculated. The robustness of the approach is documented by obtaining high resolution data of O-2 and pH distributions in marine sediments using easy synthesizable sensors. The sensors rely on the platinum(II) octaethylporphyrin (PtOEP) and lipophilic 8-Hydroxy-1,3,6-pyrenetrisulfonic acid trisodium (HPTS...

  11. High Performance Data Distribution for Scientific Community

    Science.gov (United States)

    Tirado, Juan M.; Higuero, Daniel; Carretero, Jesus

    2010-05-01

    Institutions such as NASA, ESA or JAXA find solutions to distribute data from their missions to the scientific community, and their long term archives. This is a complex problem, as it includes a vast amount of data, several geographically distributed archives, heterogeneous architectures with heterogeneous networks, and users spread around the world. We propose a novel architecture (HIDDRA) that solves this problem aiming to reduce user intervention in data acquisition and processing. HIDDRA is a modular system that provides a highly efficient parallel multiprotocol download engine, using a publish/subscribe policy which helps the final user to obtain data of interest transparently. Our system can deal simultaneously with multiple protocols (HTTP,HTTPS, FTP, GridFTP among others) to obtain the maximum bandwidth, reducing the workload in data server and increasing flexibility. It can also provide high reliability and fault tolerance, as several sources of data can be used to perform one file download. HIDDRA architecture can be arranged into a data distribution network deployed on several sites that can cooperate to provide former features. HIDDRA has been addressed by the 2009 e-IRG Report on Data Management as a promising initiative for data interoperability. Our first prototype has been evaluated in collaboration with the ESAC centre in Villafranca del Castillo (Spain) that shows a high scalability and performance, opening a wide spectrum of opportunities. Some preliminary results have been published in the Journal of Astrophysics and Space Science [1]. [1] D. Higuero, J.M. Tirado, J. Carretero, F. Félix, and A. de La Fuente. HIDDRA: a highly independent data distribution and retrieval architecture for space observation missions. Astrophysics and Space Science, 321(3):169-175, 2009

  12. High-performance laboratories and cleanrooms; TOPICAL

    International Nuclear Information System (INIS)

    Tschudi, William; Sartor, Dale; Mills, Evan; Xu, Tengfang

    2002-01-01

    The California Energy Commission sponsored this roadmap to guide energy efficiency research and deployment for high performance cleanrooms and laboratories. Industries and institutions utilizing these building types (termed high-tech buildings) have played an important part in the vitality of the California economy. This roadmap's key objective to present a multi-year agenda to prioritize and coordinate research efforts. It also addresses delivery mechanisms to get the research products into the market. Because of the importance to the California economy, it is appropriate and important for California to take the lead in assessing the energy efficiency research needs, opportunities, and priorities for this market. In addition to the importance to California's economy, energy demand for this market segment is large and growing (estimated at 9400 GWH for 1996, Mills et al. 1996). With their 24hr. continuous operation, high tech facilities are a major contributor to the peak electrical demand. Laboratories and cleanrooms constitute the high tech building market, and although each building type has its unique features, they are similar in that they are extremely energy intensive, involve special environmental considerations, have very high ventilation requirements, and are subject to regulations-primarily safety driven-that tend to have adverse energy implications. High-tech buildings have largely been overlooked in past energy efficiency research. Many industries and institutions utilize laboratories and cleanrooms. As illustrated, there are many industries operating cleanrooms in California. These include semiconductor manufacturing, semiconductor suppliers, pharmaceutical, biotechnology, disk drive manufacturing, flat panel displays, automotive, aerospace, food, hospitals, medical devices, universities, and federal research facilities

  13. Transport in JET high performance plasmas

    International Nuclear Information System (INIS)

    2001-01-01

    Two type of high performance scenarios have been produced in JET during DTE1 campaign. One of them is the well known and extensively used in the past ELM-free hot ion H-mode scenario which has two distinct regions- plasma core and the edge transport barrier. The results obtained during DTE-1 campaign with D, DT and pure T plasmas confirms our previous conclusion that the core transport scales as a gyroBohm in the inner half of plasma volume, recovers its Bohm nature closer to the separatrix and behaves as ion neoclassical in the transport barrier. Measurements on the top of the barrier suggest that the width of the barrier is dependent upon isotope and moreover suggest that fast ions play a key role. The other high performance scenario is a relatively recently developed Optimised Shear Scenario with small or slightly negative magnetic shear in plasma core. Different mechanisms of Internal Transport Barrier (ITB) formation have been tested by predictive modelling and the results are compared with experimentally observed phenomena. The experimentally observed non-penetration of the heavy impurities through the strong ITB which contradicts to a prediction of the conventional neo-classical theory is discussed. (author)

  14. High-performance computing for airborne applications

    International Nuclear Information System (INIS)

    Quinn, Heather M.; Manuzatto, Andrea; Fairbanks, Tom; Dallmann, Nicholas; Desgeorges, Rose

    2010-01-01

    Recently, there has been attempts to move common satellite tasks to unmanned aerial vehicles (UAVs). UAVs are significantly cheaper to buy than satellites and easier to deploy on an as-needed basis. The more benign radiation environment also allows for an aggressive adoption of state-of-the-art commercial computational devices, which increases the amount of data that can be collected. There are a number of commercial computing devices currently available that are well-suited to high-performance computing. These devices range from specialized computational devices, such as field-programmable gate arrays (FPGAs) and digital signal processors (DSPs), to traditional computing platforms, such as microprocessors. Even though the radiation environment is relatively benign, these devices could be susceptible to single-event effects. In this paper, we will present radiation data for high-performance computing devices in a accelerated neutron environment. These devices include a multi-core digital signal processor, two field-programmable gate arrays, and a microprocessor. From these results, we found that all of these devices are suitable for many airplane environments without reliability problems.

  15. Transport in JET high performance plasmas

    International Nuclear Information System (INIS)

    1999-01-01

    Two type of high performance scenarios have been produced in JET during DTE1 campaign. One of them is the well known and extensively used in the past ELM-free hot ion H-mode scenario which has two distinct regions- plasma core and the edge transport barrier. The results obtained during DTE-1 campaign with D, DT and pure T plasmas confirms our previous conclusion that the core transport scales as a gyroBohm in the inner half of plasma volume, recovers its Bohm nature closer to the separatrix and behaves as ion neoclassical in the transport barrier. Measurements on the top of the barrier suggest that the width of the barrier is dependent upon isotope and moreover suggest that fast ions play a key role. The other high performance scenario is a relatively recently developed Optimised Shear Scenario with small or slightly negative magnetic shear in plasma core. Different mechanisms of Internal Transport Barrier (ITB) formation have been tested by predictive modelling and the results are compared with experimentally observed phenomena. The experimentally observed non-penetration of the heavy impurities through the strong ITB which contradicts to a prediction of the conventional neo-classical theory is discussed. (author)

  16. High-performance vertical organic transistors.

    Science.gov (United States)

    Kleemann, Hans; Günther, Alrun A; Leo, Karl; Lüssem, Björn

    2013-11-11

    Vertical organic thin-film transistors (VOTFTs) are promising devices to overcome the transconductance and cut-off frequency restrictions of horizontal organic thin-film transistors. The basic physical mechanisms of VOTFT operation, however, are not well understood and VOTFTs often require complex patterning techniques using self-assembly processes which impedes a future large-area production. In this contribution, high-performance vertical organic transistors comprising pentacene for p-type operation and C60 for n-type operation are presented. The static current-voltage behavior as well as the fundamental scaling laws of such transistors are studied, disclosing a remarkable transistor operation with a behavior limited by injection of charge carriers. The transistors are manufactured by photolithography, in contrast to other VOTFT concepts using self-assembled source electrodes. Fluorinated photoresist and solvent compounds allow for photolithographical patterning directly and strongly onto the organic materials, simplifying the fabrication protocol and making VOTFTs a prospective candidate for future high-performance applications of organic transistors. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Performance of the CMS High Level Trigger

    CERN Document Server

    Perrotta, Andrea

    2015-01-01

    The CMS experiment has been designed with a 2-level trigger system. The first level is implemented using custom-designed electronics. The second level is the so-called High Level Trigger (HLT), a streamlined version of the CMS offline reconstruction software running on a computer farm. For Run II of the Large Hadron Collider, the increases in center-of-mass energy and luminosity will raise the event rate to a level challenging for the HLT algorithms. The increase in the number of interactions per bunch crossing, on average 25 in 2012, and expected to be around 40 in Run II, will be an additional complication. We present here the expected performance of the main triggers that will be used during the 2015 data taking campaign, paying particular attention to the new approaches that have been developed to cope with the challenges of the new run. This includes improvements in HLT electron and photon reconstruction as well as better performing muon triggers. We will also present the performance of the improved trac...

  18. Development of a High Performance Spacer Grid

    Energy Technology Data Exchange (ETDEWEB)

    Song, Kee Nam; Song, K. N.; Yoon, K. H. (and others)

    2007-03-15

    A spacer grid in a LWR fuel assembly is a key structural component to support fuel rods and to enhance the heat transfer from the fuel rod to the coolant. In this research, the main research items are the development of inherent and high performance spacer grid shapes, the establishment of mechanical/structural analysis and test technology, and the set-up of basic test facilities for the spacer grid. The main research areas and results are as follows. 1. 18 different spacer grid candidates have been invented and applied for domestic and US patents. Among the candidates 16 are chosen from the patent. 2. Two kinds of spacer grids are finally selected for the advanced LWR fuel after detailed performance tests on the candidates and commercial spacer grids from a mechanical/structural point of view. According to the test results the features of the selected spacer grids are better than those of the commercial spacer grids. 3. Four kinds of basic test facilities are set up and the relevant test technologies are established. 4. Mechanical/structural analysis models and technology for spacer grid performance are developed and the analysis results are compared with the test results to enhance the reliability of the models.

  19. Low cost high performance uncertainty quantification

    KAUST Repository

    Bekas, C.

    2009-01-01

    Uncertainty quantification in risk analysis has become a key application. In this context, computing the diagonal of inverse covariance matrices is of paramount importance. Standard techniques, that employ matrix factorizations, incur a cubic cost which quickly becomes intractable with the current explosion of data sizes. In this work we reduce this complexity to quadratic with the synergy of two algorithms that gracefully complement each other and lead to a radically different approach. First, we turned to stochastic estimation of the diagonal. This allowed us to cast the problem as a linear system with a relatively small number of multiple right hand sides. Second, for this linear system we developed a novel, mixed precision, iterative refinement scheme, which uses iterative solvers instead of matrix factorizations. We demonstrate that the new framework not only achieves the much needed quadratic cost but in addition offers excellent opportunities for scaling at massively parallel environments. We based our implementation on BLAS 3 kernels that ensure very high processor performance. We achieved a peak performance of 730 TFlops on 72 BG/P racks, with a sustained performance 73% of theoretical peak. We stress that the techniques presented in this work are quite general and applicable to several other important applications. Copyright © 2009 ACM.

  20. Energy Efficient Graphene Based High Performance Capacitors.

    Science.gov (United States)

    Bae, Joonwon; Kwon, Oh Seok; Lee, Chang-Soo

    2017-07-10

    Graphene (GRP) is an interesting class of nano-structured electronic materials for various cutting-edge applications. To date, extensive research activities have been performed on the investigation of diverse properties of GRP. The incorporation of this elegant material can be very lucrative in terms of practical applications in energy storage/conversion systems. Among various those systems, high performance electrochemical capacitors (ECs) have become popular due to the recent need for energy efficient and portable devices. Therefore, in this article, the application of GRP for capacitors is described succinctly. In particular, a concise summary on the previous research activities regarding GRP based capacitors is also covered extensively. It was revealed that a lot of secondary materials such as polymers and metal oxides have been introduced to improve the performance. Also, diverse devices have been combined with capacitors for better use. More importantly, recent patents related to the preparation and application of GRP based capacitors are also introduced briefly. This article can provide essential information for future study. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  1. SISYPHUS: A high performance seismic inversion factory

    Science.gov (United States)

    Gokhberg, Alexey; Simutė, Saulė; Boehm, Christian; Fichtner, Andreas

    2016-04-01

    In the recent years the massively parallel high performance computers became the standard instruments for solving the forward and inverse problems in seismology. The respective software packages dedicated to forward and inverse waveform modelling specially designed for such computers (SPECFEM3D, SES3D) became mature and widely available. These packages achieve significant computational performance and provide researchers with an opportunity to solve problems of bigger size at higher resolution within a shorter time. However, a typical seismic inversion process contains various activities that are beyond the common solver functionality. They include management of information on seismic events and stations, 3D models, observed and synthetic seismograms, pre-processing of the observed signals, computation of misfits and adjoint sources, minimization of misfits, and process workflow management. These activities are time consuming, seldom sufficiently automated, and therefore represent a bottleneck that can substantially offset performance benefits provided by even the most powerful modern supercomputers. Furthermore, a typical system architecture of modern supercomputing platforms is oriented towards the maximum computational performance and provides limited standard facilities for automation of the supporting activities. We present a prototype solution that automates all aspects of the seismic inversion process and is tuned for the modern massively parallel high performance computing systems. We address several major aspects of the solution architecture, which include (1) design of an inversion state database for tracing all relevant aspects of the entire solution process, (2) design of an extensible workflow management framework, (3) integration with wave propagation solvers, (4) integration with optimization packages, (5) computation of misfits and adjoint sources, and (6) process monitoring. The inversion state database represents a hierarchical structure with

  2. From simple to complex and backwards. Chemical reactions under very high pressure

    International Nuclear Information System (INIS)

    Bini, Roberto; Ceppatelli, Matteo; Citroni, Margherita; Schettino, Vincenzo

    2012-01-01

    Highlights: ► High pressure reactivity of several molecular systems. ► Reaction kinetics and dynamics in high density conditions. ► Key role of optical pumping and electronic excitation. ► Perspectives for the synthesis of hydrogen. - Abstract: High pressure chemical reactions of molecular systems are discussed considering the various factors that can affect the reactivity. These include steric hindrance and geometrical constraints in the confined environment of crystals at high pressure, changes of the free energy landscape with pressure, photoactivation by two-photon absorption, local and collective effects. A classification of the chemical reactions at high pressure is attempted on the basis of the prevailing factors.

  3. Ultra high performance concrete dematerialization study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-03-01

    Concrete is the most widely used building material in the world and its use is expected to grow. It is well recognized that the production of portland cement results in the release of large amounts of carbon dioxide, a greenhouse gas (GHG). The main challenge facing the industry is to produce concrete in an environmentally sustainable manner. Reclaimed industrial by-proudcts such as fly ash, silica fume and slag can reduce the amount of portland cement needed to make concrete, thereby reducing the amount of GHGs released to the atmosphere. The use of these supplementary cementing materials (SCM) can also enhance the long-term strength and durability of concrete. The intention of the EcoSmart{sup TM} Concrete Project is to develop sustainable concrete through innovation in supply, design and construction. In particular, the project focuses on finding a way to minimize the GHG signature of concrete by maximizing the replacement of portland cement in the concrete mix with SCM while improving the cost, performance and constructability. This paper describes the use of Ductal{sup R} Ultra High Performance Concrete (UHPC) for ramps in a condominium. It examined the relationship between the selection of UHPC and the overall environmental performance, cost, constructability maintenance and operational efficiency as it relates to the EcoSmart Program. The advantages and challenges of using UHPC were outlined. In addition to its very high strength, UHPC has been shown to have very good potential for GHG emission reduction due to the reduced material requirements, reduced transport costs and increased SCM content. refs., tabs., figs.

  4. JT-60U high performance regimes

    International Nuclear Information System (INIS)

    Ishida, S.

    1999-01-01

    High performance regimes of JT-60U plasmas are presented with an emphasis upon the results from the use of a semi-closed pumped divertor with W-shaped geometry. Plasma performance in transient and quasi steady states has been significantly improved in reversed shear and high- βp regimes. The reversed shear regime elevated an equivalent Q DT eq transiently up to 1.25 (n D (0)τ E T i (0)=8.6x10 20 m-3·s·keV) in a reactor-relevant thermonuclear dominant regime. Long sustainment of enhanced confinement with internal transport barriers (ITBs) with a fully non-inductive current drive in a reversed shear discharge was successfully demonstrated with LH wave injection. Performance sustainment has been extended in the high- bp regime with a high triangularity achieving a long sustainment of plasma conditions equivalent to Q DT eq ∼0.16 (n D (0)τ E T i (0)∼1.4x10 20 m -3 ·s·keV) for ∼4.5 s with a large non-inductive current drive fraction of 60-70% of the plasma current. Thermal and particle transport analyses show significant reduction of thermal and particle diffusivities around ITB resulting in a strong Er shear in the ITB region. The W-shaped divertor is effective for He ash exhaust demonstrating steady exhaust capability of τ He */τ E ∼3-10 in support of ITER. Suppression of neutral back flow and chemical sputtering effect have been observed while MARFE onset density is rather decreased. Negative-ion based neutral beam injection (N-NBI) experiments have created a clear H-mode transition. Enhanced ionization cross- section due to multi-step ionization processes was confirmed as theoretically predicted. A current density profile driven by N-NBI is measured in a good agreement with theoretical prediction. N-NBI induced TAE modes characterized as persistent and bursting oscillations have been observed from a low hot beta of h >∼0.1-0.2% without a significant loss of fast ions. (author)

  5. Rapid, simple and highly sensitive LC-ESI-MS/MS method for the quantification of tamsulosin in human plasma.

    Science.gov (United States)

    Ramakrishna, N V S; Vishwottam, K N; Manoj, S; Koteshwara, M; Wishu, S; Varma, D P

    2005-12-01

    A simple, rapid, sensitive and specific liquid chromatography-tandem mass spectrometry method was developed and validated for quantification of tamsulosin (I), a highly selective alpha1-adrenoceptor antagonist used for the treatment of patients with symptomatic benign prostatic hyperplasia. The analyte and internal standard, mosapride (II) were extracted by liquid-liquid extraction with diethyl ether-dichloromethane (70:30, v/v) using a Glas-Col Multi-Pulse Vortexer. The chromatographic separation was performed on a reverse phase Waters symmetry C18 column with a mobile phase of 0.03% formic acid-acetonitrile (30:70, v/v). The protonated analyte was quantitated in positive ionization by multiple reaction monitoring with a mass spectrometer. The mass transitions m/z 409.1 solidus in circle 228.1 and m/z 422.3 solidus in circle 198.3 were used to measure I and II, respectively. The assay exhibited a linear dynamic range of 0.1-50.0 ng/mL for tamsulosin in human plasma. The lower limit of quantitation was 100 pg/mL with a relative standard deviation of less than 10%. Acceptable precision and accuracy were obtained for concentrations over the standard curve ranges. A run time of 2.0 min for each sample made it possible to analyze a throughput of more than 400 human plasma samples per day. The validated method has been successfully used to analyze human plasma samples for application in pharmacokinetic, bioavailability or bioequivalence studies. (c) 2005 John Wiley & Sons, Ltd.

  6. High-performance nanostructured supercapacitors on a sponge

    KAUST Repository

    Chen, Wei

    2011-12-14

    A simple and scalable method has been developed to fabricate nanostructured MnO 2-carbon nanotube (CNT)-sponge hybrid electrodes. A novel supercapacitor, henceforth referred to as "sponge supercapacitor", has been fabricated using these hybrid electrodes with remarkable performance. A specific capacitance of 1230 F/g (based on the mass of MnO 2) can be reached. Capacitors based on CNT-sponge substrates (without MnO 2) can be operated even under a high scan rate of 200 V/s, and they exhibit outstanding cycle performance with only 2% degradation after 100000 cycles under a scan rate of 10 V/s. The MnO 2-CNT-sponge supercapacitors show only 4% of degradation after 10000 cycles at a charge-discharge specific current of 5 A/g. The specific power and energy of the MnO 2-CNT-sponge supercapacitors are high with values of 63 kW/kg and 31 Wh/kg, respectively. The attractive performances exhibited by these sponge supercapacitors make them potentially promising candidates for future energy storage systems. © 2011 American Chemical Society.

  7. High-performance phase-field modeling

    KAUST Repository

    Vignal, Philippe

    2015-04-27

    Many processes in engineering and sciences involve the evolution of interfaces. Among the mathematical frameworks developed to model these types of problems, the phase-field method has emerged as a possible solution. Phase-fields nonetheless lead to complex nonlinear, high-order partial differential equations, whose solution poses mathematical and computational challenges. Guaranteeing some of the physical properties of the equations has lead to the development of efficient algorithms and discretizations capable of recovering said properties by construction [2, 5]. This work builds-up on these ideas, and proposes novel discretization strategies that guarantee numerical energy dissipation for both conserved and non-conserved phase-field models. The temporal discretization is based on a novel method which relies on Taylor series and ensures strong energy stability. It is second-order accurate, and can also be rendered linear to speed-up the solution process [4]. The spatial discretization relies on Isogeometric Analysis, a finite element method that possesses the k-refinement technology and enables the generation of high-order, high-continuity basis functions. These basis functions are well suited to handle the high-order operators present in phase-field models. Two-dimensional and three dimensional results of the Allen-Cahn, Cahn-Hilliard, Swift-Hohenberg and phase-field crystal equation will be presented, which corroborate the theoretical findings, and illustrate the robustness of the method. Results related to more challenging examples, namely the Navier-Stokes Cahn-Hilliard and a diusion-reaction Cahn-Hilliard system, will also be presented. The implementation was done in PetIGA and PetIGA-MF, high-performance Isogeometric Analysis frameworks [1, 3], designed to handle non-linear, time-dependent problems.

  8. Performance of digital integrated circuit technologies at very high temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Prince, J.L.; Draper, B.L.; Rapp, E.A.; Kromberg, J.N.; Fitch, L.T.

    1980-01-01

    Results of investigations of the performance and reliability of digital bipolar and CMOS integrated circuits over the 25 to 340/sup 0/C range are reported. Included in these results are both parametric variation information and analysis of the functional failure mechanisms. Although most of the work was done using commercially available circuits (TTL and CMOS) and test chips from commercially compatible processes, some results of experimental simulations of dielectrically isolated CMOS are also discussed. It was found that commercial Schottky clamped TTL, and dielectrically isolated, low power Schottky-clamped TTL, functioned to junction temperatures in excess of 325/sup 0/C. Standard gold doped TTL functioned only to 250/sup 0/C, while commercial, isolated I/sup 2/L functioned to the range 250/sup 0/C to 275/sup 0/C. Commercial junction isolated CMOS, buffered and unbuffered, functioned to the range 280/sup 0/C to 310/sup 0/C/sup +/, depending on the manufacturer. Experimental simulations of simple dielectrically isolated CMOS integrated circuits, fabricated with heavier doping levels than normal, functioned to temperatures in excess of 340/sup 0/C. High temperature life testing of experimental, silicone-encapsulated simple TTL and CMOS integrated circuits have shown no obvious life limiting problems to date. No barrier to reliable functionality of TTL bipolar or CMOS integrated ciruits at temperatures in excess of 300/sup 0/C has been found.

  9. Targeted and untargeted high resolution mass approach for a putative profiling of glycosylated simple phenols in hybrid grapes.

    Science.gov (United States)

    Barnaba, Chiara; Dellacassa, Eduardo; Nicolini, Giorgio; Giacomelli, Mattia; Roman Villegas, Tomas; Nardin, Tiziana; Larcher, Roberto

    2017-08-01

    Vitis vinifera is one of the most widespread grapevines around the world representing the raw material for high quality wine production. The availability of more resistant interspecific hybrid vine varieties, developed from crosses between Vitis vinifera and other Vitis species, has generated much interest, also due to the low environmental effect of production. However, hybrid grape wine composition and varietal differences between interspecific hybrids have not been well defined, particularly for the simple phenols profile. The dynamic of these phenols in wines, where the glycosylated forms can be transformed into the free ones during winemaking, also raises an increasing health interest by their role as antoxidants in wine consumers. In this work an on-line SPE clean-up device, to reduce matrix interference, was combined with ultra-high liquid chromatography-high resolution mass spectrometry in order to increase understanding of the phenolic composition of hybrid grape varieties. Specifically, the phenolic composition of 4 hybrid grape varieties (red, Cabernet Cantor and Prior; white, Muscaris and Solaris) and 2 European grape varieties (red, Merlot; white, Chardonnay) was investigated, focusing on free and glycosidically bound simple phenols and considering compound distribution in pulp, skin, seeds and wine. Using a targeted approach 53 free simple phenols and 7 glycosidic precursors were quantified with quantification limits ranging from 0.001 to 2mgKg -1 and calibration R 2 of 0.99 for over 86% of compounds. The untargeted approach made it possible to tentatively identify 79 glycosylated precursors of selected free simple phenols in the form of -hexoside (N=30), -pentoside (21), -hexoside-hexoside (17), -hexoside-pentoside (4), -pentoside-hexoside (5) and -pentoside-pentoside (2) derivatives on the basis of accurate mass, isotopic pattern and MS/MS fragmentation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. A Simple Engineering Analysis of Solar Particle Event High Energy Tails and Their Impact on Vehicle Design

    Science.gov (United States)

    Singleterry, Robert C., Jr.; Walker, Steven A.; Clowdsley, Martha S.

    2016-01-01

    The mathematical models for Solar Particle Event (SPE) high energy tails are constructed with several di erent algorithms. Since limited measured data exist above energies around 400 MeV, this paper arbitrarily de nes the high energy tail as any proton with an energy above 400 MeV. In order to better understand the importance of accurately modeling the high energy tail for SPE spectra, the contribution to astronaut whole body e ective dose equivalent of the high energy portions of three di erent SPE models has been evaluated. To ensure completeness of this analysis, simple and complex geometries were used. This analysis showed that the high energy tail of certain SPEs can be relevant to astronaut exposure and hence safety. Therefore, models of high energy tails for SPEs should be well analyzed and based on data if possible.

  11. High strain rate superplasticity in an Al–Mg–Sc–Zr alloy processed via simple rolling

    Energy Technology Data Exchange (ETDEWEB)

    Li, Mengjia [School of Materials Science and Engineering, Central South University, Changsha 410083 (China); Pan, Qinglin, E-mail: csupql@163.com [Nonferrous Metal Oriented Advanced Structural Materials and Manufacturing Cooperative Innovation Center, Central South University, Changsha 410083 (China); Shi, Yunjia; Sun, Xue; Xiang, Hao [School of Materials Science and Engineering, Central South University, Changsha 410083 (China)

    2017-02-27

    The superplastic behavior of Al–Mg–Sc–Zr samples with standard gauge size (18 mm by 6 mm) were prepared using simple rolling and were tested in the temperature range from 450 °C to 525 °C at strain rates ranging from 1.67×10{sup –3} s{sup −1} to 1×10{sup –1} s{sup −1}. With proper deformation parameters, the Al–Mg–Sc–Zr alloy has an elongation to failure much higher than 300% and the maximum elongation is 740%. The Microstructure and dislocation substructure investigation using optical microscopy (OM) and transmission electron microscopy (TEM) revealed a dynamic recrystallization in it. The grain size and activation energy on the deformation mechanisms of superplastic is discussed. Results also show that these nano-scale Al{sub 3}(Sc{sub 1−x}Zr{sub x}) particles play an important role in the superplastic process. Al{sub 6}FeMn particles were found to induce the formation and growth of cavities, which can lead to the fracture of specimens.

  12. Pocket change: a simple educational intervention increases hospitalist documentation of comorbidities and improves hospital quality performance measures.

    Science.gov (United States)

    Sparks, Rachel; Salskov, Alex H; Chang, Anita S; Wentworth, Kelly L; Gupta, Pritha P; Staiger, Thomas O; Anawalt, Bradley D

    2015-01-01

    Complete documentation of patient comorbidities in the medical record is important for clinical care, hospital reimbursement, and quality performance measures. We designed a pocket card reminder and brief educational intervention aimed at hospitalists with the goal of improving documentation of 6 common comorbidities present on admission: coagulation abnormalities, metastatic cancer, anemia, fluid and electrolyte abnormalities, malnutrition, and obesity. Two internal medicine inpatient teams led by 10 hospitalist physicians at an academic medical center received the educational intervention and pocket card reminder (n = 520 admissions). Two internal medicine teams led by nonhospitalist physicians served as a control group (n = 590 admissions). Levels of documentation of 6 common comorbidities, expected length of stay, and expected mortality were measured at baseline and during the 9-month study period. The intervention was associated with increased documentation of anemia, fluid and electrolyte abnormalities, malnutrition, and obesity in the intervention group, both compared to baseline and compared to the control group during the study period. The expected length of stay increased in the intervention group during the study period. A simple educational intervention and pocket card reminder were associated with improved documentation and hospital quality measures at an academic medical center.

  13. High performance visual display for HENP detectors

    International Nuclear Information System (INIS)

    McGuigan, Michael; Smith, Gordon; Spiletic, John; Fine, Valeri; Nevski, Pavel

    2001-01-01

    A high end visual display for High Energy Nuclear Physics (HENP) detectors is necessary because of the sheer size and complexity of the detector. For BNL this display will be of special interest because of STAR and ATLAS. To load, rotate, query, and debug simulation code with a modern detector simply takes too long even on a powerful work station. To visualize the HENP detectors with maximal performance we have developed software with the following characteristics. We develop a visual display of HENP detectors on BNL multiprocessor visualization server at multiple level of detail. We work with general and generic detector framework consistent with ROOT, GAUDI etc, to avoid conflicting with the many graphic development groups associated with specific detectors like STAR and ATLAS. We develop advanced OpenGL features such as transparency and polarized stereoscopy. We enable collaborative viewing of detector and events by directly running the analysis in BNL stereoscopic theatre. We construct enhanced interactive control, including the ability to slice, search and mark areas of the detector. We incorporate the ability to make a high quality still image of a view of the detector and the ability to generate animations and a fly through of the detector and output these to MPEG or VRML models. We develop data compression hardware and software so that remote interactive visualization will be possible among dispersed collaborators. We obtain real time visual display for events accumulated during simulations

  14. Development of high performance ODS alloys

    Energy Technology Data Exchange (ETDEWEB)

    Shao, Lin [Texas A & M Univ., College Station, TX (United States); Gao, Fei [Univ. of Michigan, Ann Arbor, MI (United States); Garner, Frank [Texas A & M Univ., College Station, TX (United States)

    2018-01-29

    This project aims to capitalize on insights developed from recent high-dose self-ion irradiation experiments in order to develop and test the next generation of optimized ODS alloys needed to meet the nuclear community's need for high strength, radiation-tolerant cladding and core components, especially with enhanced resistance to void swelling. Two of these insights are that ferrite grains swell earlier than tempered martensite grains, and oxide dispersions currently produced only in ferrite grains require a high level of uniformity and stability to be successful. An additional insight is that ODS particle stability is dependent on as-yet unidentified compositional combinations of dispersoid and alloy matrix, such as dispersoids are stable in MA957 to doses greater than 200 dpa but dissolve in MA956 at doses less than 200 dpa. These findings focus attention on candidate next-generation alloys which address these concerns. Collaboration with two Japanese groups provides this project with two sets of first-round candidate alloys that have already undergone extensive development and testing for unirradiated properties, but have not yet been evaluated for their irradiation performance. The first set of candidate alloys are dual phase (ferrite + martensite) ODS alloys with oxide particles uniformly distributed in both ferrite and martensite phases. The second set of candidate alloys are ODS alloys containing non-standard dispersoid compositions with controllable oxide particle sizes, phases and interfaces.

  15. Efficient high-performance ultrasound beamforming using oversampling

    Science.gov (United States)

    Freeman, Steven R.; Quick, Marshall K.; Morin, Marc A.; Anderson, R. C.; Desilets, Charles S.; Linnenbrink, Thomas E.; O'Donnell, Matthew

    1998-05-01

    High-performance and efficient beamforming circuitry is very important in large channel count clinical ultrasound systems. Current state-of-the-art digital systems using multi-bit analog to digital converters (A/Ds) have matured to provide exquisite image quality with moderate levels of integration. A simplified oversampling beamforming architecture has been proposed that may a low integration of delta-sigma A/Ds onto the same chip as digital delay and processing circuitry to form a monolithic ultrasound beamformer. Such a beamformer may enable low-power handheld scanners for high-end systems with very large channel count arrays. This paper presents an oversampling beamformer architecture that generates high-quality images using very simple; digitization, delay, and summing circuits. Additional performance may be obtained with this oversampled system for narrow bandwidth excitations by mixing the RF signal down in frequency to a range where the electronic signal to nose ratio of the delta-sigma A/D is optimized. An oversampled transmit beamformer uses the same delay circuits as receive and eliminates the need for separate transmit function generators.

  16. High Performance Computing in Science and Engineering '15 : Transactions of the High Performance Computing Center

    CERN Document Server

    Kröner, Dietmar; Resch, Michael

    2016-01-01

    This book presents the state-of-the-art in supercomputer simulation. It includes the latest findings from leading researchers using systems from the High Performance Computing Center Stuttgart (HLRS) in 2015. The reports cover all fields of computational science and engineering ranging from CFD to computational physics and from chemistry to computer science with a special emphasis on industrially relevant applications. Presenting findings of one of Europe’s leading systems, this volume covers a wide variety of applications that deliver a high level of sustained performance. The book covers the main methods in high-performance computing. Its outstanding results in achieving the best performance for production codes are of particular interest for both scientists and engineers. The book comes with a wealth of color illustrations and tables of results.

  17. High Performance Computing in Science and Engineering '17 : Transactions of the High Performance Computing Center

    CERN Document Server

    Kröner, Dietmar; Resch, Michael; HLRS 2017

    2018-01-01

    This book presents the state-of-the-art in supercomputer simulation. It includes the latest findings from leading researchers using systems from the High Performance Computing Center Stuttgart (HLRS) in 2017. The reports cover all fields of computational science and engineering ranging from CFD to computational physics and from chemistry to computer science with a special emphasis on industrially relevant applications. Presenting findings of one of Europe’s leading systems, this volume covers a wide variety of applications that deliver a high level of sustained performance.The book covers the main methods in high-performance computing. Its outstanding results in achieving the best performance for production codes are of particular interest for both scientists and engineers. The book comes with a wealth of color illustrations and tables of results.

  18. Thermal interface pastes nanostructured for high performance

    Science.gov (United States)

    Lin, Chuangang

    Thermal interface materials in the form of pastes are needed to improve thermal contacts, such as that between a microprocessor and a heat sink of a computer. High-performance and low-cost thermal pastes have been developed in this dissertation by using polyol esters as the vehicle and various nanoscale solid components. The proportion of a solid component needs to be optimized, as an excessive amount degrades the performance, due to the increase in the bond line thickness. The optimum solid volume fraction tends to be lower when the mating surfaces are smoother, and higher when the thermal conductivity is higher. Both a low bond line thickness and a high thermal conductivity help the performance. When the surfaces are smooth, a low bond line thickness can be even more important than a high thermal conductivity, as shown by the outstanding performance of the nanoclay paste of low thermal conductivity in the smooth case (0.009 mum), with the bond line thickness less than 1 mum, as enabled by low storage modulus G', low loss modulus G" and high tan delta. However, for rough surfaces, the thermal conductivity is important. The rheology affects the bond line thickness, but it does not correlate well with the performance. This study found that the structure of carbon black is an important parameter that governs the effectiveness of a carbon black for use in a thermal paste. By using a carbon black with a lower structure (i.e., a lower DBP value), a thermal paste that is more effective than the previously reported carbon black paste was obtained. Graphite nanoplatelet (GNP) was found to be comparable in effectiveness to carbon black (CB) pastes for rough surfaces, but it is less effective for smooth surfaces. At the same filler volume fraction, GNP gives higher thermal conductivity than carbon black paste. At the same pressure, GNP gives higher bond line thickness than CB (Tokai or Cabot). The effectiveness of GNP is limited, due to the high bond line thickness. A

  19. High performance liquid chromatography in pharmaceutical analyses

    Directory of Open Access Journals (Sweden)

    Branko Nikolin

    2004-05-01

    Full Text Available In testing the pre-sale procedure the marketing of drugs and their control in the last ten years, high performance liquid chromatographyreplaced numerous spectroscopic methods and gas chromatography in the quantitative and qualitative analysis. In the first period of HPLC application it was thought that it would become a complementary method of gas chromatography, however, today it has nearly completely replaced gas chromatography in pharmaceutical analysis. The application of the liquid mobile phase with the possibility of transformation of mobilized polarity during chromatography and all other modifications of mobile phase depending upon the characteristics of substance which are being tested, is a great advantage in the process of separation in comparison to other methods. The greater choice of stationary phase is the next factor which enables realization of good separation. The separation line is connected to specific and sensitive detector systems, spectrafluorimeter, diode detector, electrochemical detector as other hyphernated systems HPLC-MS and HPLC-NMR, are the basic elements on which is based such wide and effective application of the HPLC method. The purpose high performance liquid chromatography(HPLC analysis of any drugs is to confirm the identity of a drug and provide quantitative results and also to monitor the progress of the therapy of a disease.1 Measuring presented on the Fig. 1. is chromatogram obtained for the plasma of depressed patients 12 h before oral administration of dexamethasone. It may also be used to further our understanding of the normal and disease process in the human body trough biomedical and therapeutically research during investigation before of the drugs registration. The analyses of drugs and metabolites in biological fluids, particularly plasma, serum or urine is one of the most demanding but one of the most common uses of high performance of liquid chromatography. Blood, plasma or

  20. Integrating advanced facades into high performance buildings

    International Nuclear Information System (INIS)

    Selkowitz, Stephen E.

    2001-01-01

    Glass is a remarkable material but its functionality is significantly enhanced when it is processed or altered to provide added intrinsic capabilities. The overall performance of glass elements in a building can be further enhanced when they are designed to be part of a complete facade system. Finally the facade system delivers the greatest performance to the building owner and occupants when it becomes an essential element of a fully integrated building design. This presentation examines the growing interest in incorporating advanced glazing elements into more comprehensive facade and building systems in a manner that increases comfort, productivity and amenity for occupants, reduces operating costs for building owners, and contributes to improving the health of the planet by reducing overall energy use and negative environmental impacts. We explore the role of glazing systems in dynamic and responsive facades that provide the following functionality: Enhanced sun protection and cooling load control while improving thermal comfort and providing most of the light needed with daylighting; Enhanced air quality and reduced cooling loads using natural ventilation schemes employing the facade as an active air control element; Reduced operating costs by minimizing lighting, cooling and heating energy use by optimizing the daylighting-thermal tradeoffs; Net positive contributions to the energy balance of the building using integrated photovoltaic systems; Improved indoor environments leading to enhanced occupant health, comfort and performance. In addressing these issues facade system solutions must, of course, respect the constraints of latitude, location, solar orientation, acoustics, earthquake and fire safety, etc. Since climate and occupant needs are dynamic variables, in a high performance building the facade solution have the capacity to respond and adapt to these variable exterior conditions and to changing occupant needs. This responsive performance capability

  1. Terahertz gas sensing based on a simple one-dimensional photonic crystal cavity with high-quality factors

    DEFF Research Database (Denmark)

    Chen, T.; Han, Z. H.; Liu, J. J.

    2014-01-01

    We report in this paper terahertz gas sensing using a simple 1D photonic crystal cavity. The resonant frequencies of the cavity depend linearly on the refractive index of the ambient gas, which can then be measured by monitoring the resonance shift. Although quite easy to manufacture, this cavity...... exhibits high-quality factors, facilitating the realization of high sensitivity in the gas refractive index sensing. In our experiment, 6% of the change of hydrogen concentration in air, which corresponds to a refractive index change of 1.4 x 10(-5), can be steadily detected, and different gas samples can...

  2. Performance Issues in High Performance Fortran Implementations of Sensor-Based Applications

    Directory of Open Access Journals (Sweden)

    David R. O'hallaron

    1997-01-01

    Full Text Available Applications that get their inputs from sensors are an important and often overlooked application domain for High Performance Fortran (HPF. Such sensor-based applications typically perform regular operations on dense arrays, and often have latency and through put requirements that can only be achieved with parallel machines. This article describes a study of sensor-based applications, including the fast Fourier transform, synthetic aperture radar imaging, narrowband tracking radar processing, multibaseline stereo imaging, and medical magnetic resonance imaging. The applications are written in a dialect of HPF developed at Carnegie Mellon, and are compiled by the Fx compiler for the Intel Paragon. The main results of the study are that (1 it is possible to realize good performance for realistic sensor-based applications written in HPF and (2 the performance of the applications is determined by the performance of three core operations: independent loops (i.e., loops with no dependences between iterations, reductions, and index permutations. The article discusses the implications for HPF implementations and introduces some simple tests that implementers and users can use to measure the efficiency of the loops, reductions, and index permutations generated by an HPF compiler.

  3. SU-F-T-486: A Simple Approach to Performing Light Versus Radiation Field Coincidence Quality Assurance Using An Electronic Portal Imaging Device (EPID)

    Energy Technology Data Exchange (ETDEWEB)

    Herchko, S; Ding, G [Vanderbilt University, Nashville, TN (United States)

    2016-06-15

    Purpose: To develop an accurate, straightforward, and user-independent method for performing light versus radiation field coincidence quality assurance utilizing EPID images, a simple phantom made of readily-accessible materials, and a free software program. Methods: A simple phantom consisting of a blocking tray, graph paper, and high-density wire was constructed. The phantom was used to accurately set the size of a desired light field and imaged on the electronic portal imaging device (EPID). A macro written for use in ImageJ, a free image processing software, was then use to determine the radiation field size utilizing the high density wires on the phantom for a pixel to distance calibration. The macro also performs an analysis on the measured radiation field utilizing the tolerances recommended in the AAPM Task Group #142. To verify the accuracy of this method, radiochromic film was used to qualitatively demonstrate agreement between the film and EPID results, and an additional ImageJ macro was used to quantitatively compare the radiation field sizes measured both with the EPID and film images. Results: The results of this technique were benchmarked against film measurements, which have been the gold standard for testing light versus radiation field coincidence. The agreement between this method and film measurements were within 0.5 mm. Conclusion: Due to the operator dependency associated with tracing light fields and measuring radiation fields by hand when using film, this method allows for a more accurate comparison between the light and radiation fields with minimal operator dependency. Removing the need for radiographic or radiochromic film also eliminates a reoccurring cost and increases procedural efficiency.

  4. SU-F-T-486: A Simple Approach to Performing Light Versus Radiation Field Coincidence Quality Assurance Using An Electronic Portal Imaging Device (EPID)

    International Nuclear Information System (INIS)

    Herchko, S; Ding, G

    2016-01-01

    Purpose: To develop an accurate, straightforward, and user-independent method for performing light versus radiation field coincidence quality assurance utilizing EPID images, a simple phantom made of readily-accessible materials, and a free software program. Methods: A simple phantom consisting of a blocking tray, graph paper, and high-density wire was constructed. The phantom was used to accurately set the size of a desired light field and imaged on the electronic portal imaging device (EPID). A macro written for use in ImageJ, a free image processing software, was then use to determine the radiation field size utilizing the high density wires on the phantom for a pixel to distance calibration. The macro also performs an analysis on the measured radiation field utilizing the tolerances recommended in the AAPM Task Group #142. To verify the accuracy of this method, radiochromic film was used to qualitatively demonstrate agreement between the film and EPID results, and an additional ImageJ macro was used to quantitatively compare the radiation field sizes measured both with the EPID and film images. Results: The results of this technique were benchmarked against film measurements, which have been the gold standard for testing light versus radiation field coincidence. The agreement between this method and film measurements were within 0.5 mm. Conclusion: Due to the operator dependency associated with tracing light fields and measuring radiation fields by hand when using film, this method allows for a more accurate comparison between the light and radiation fields with minimal operator dependency. Removing the need for radiographic or radiochromic film also eliminates a reoccurring cost and increases procedural efficiency.

  5. Confine Clay in an Alternating Multilayered Structure through Injection Molding: A Simple and Efficient Route to Improve Barrier Performance of Polymeric Materials.

    Science.gov (United States)

    Yu, Feilong; Deng, Hua; Bai, Hongwei; Zhang, Qin; Wang, Ke; Chen, Feng; Fu, Qiang

    2015-05-20

    Various methods have been devoted to trigger the formation of multilayered structure for wide range of applications. These methods are often complicated with low production efficiency or require complex equipment. Herein, we demonstrate a simple and efficient method for the fabrication of polymeric sheets containing multilayered structure with enhanced barrier property through high speed thin-wall injection molding (HSIM). To achieve this, montmorillonite (MMT) is added into PE first, then blended with PP to fabricate PE-MMT/PP ternary composites. It is demonstrated that alternating multilayer structure could be obtained in the ternary composites because of low interfacial tension and good viscosity match between different polymer components. MMT is selectively dispersed in PE phase with partial exfoliated/partial intercalated microstructure. 2D-WAXD analysis indicates that the clay tactoids in PE-MMT/PP exhibits an uniplanar-axial orientation with their surface parallel to the molded part surface, while the tactoids in binary PE-MMT composites with the same overall MMT contents illustrate less orientation. The enhanced orientation of nanoclay in PE-MMT/PP could be attributed to the confinement of alternating multilayer structure, which prohibits the tumbling and rotation of nanoplatelets. Therefore, the oxygen barrier property of PE-MMT/PP is superior to that of PE-MMT because of increased gas permeation pathway. Comparing with the results obtained for PE based composites in literature, outstanding barrier property performance (45.7% and 58.2% improvement with 1.5 and 2.5 wt % MMT content, respectively) is achieved in current study. Two issues are considered responsible for such improvement: enhanced MMT orientation caused by the confinement in layered structure, and higher local density of MMT in layered structure induced denser assembly. Finally, enhancement in barrier property by confining impermeable filler into alternating multilayer structure through such

  6. The need for high performance breeder reactors

    International Nuclear Information System (INIS)

    Vaughan, R.D.; Chermanne, J.

    1977-01-01

    It can be easily demonstrated, on the basis of realistic estimates of continued high oil costs, that an increasing portion of the growth in energy demand must be supplied by nuclear power and that this one might account for 20% of all the energy production by the end of the century. Such assumptions lead very quickly to the conclusion that the discovery, extraction and processing of the uranium will not be able to follow the demand; the bottleneck will essentially be related to the rate at which the ore can be discovered and extracted, and not to the existing quantities nor their grade. Figures as high as 150.000 T/annum and more would be quickly reached, and it is necessary to wonder already now if enough capital can be attracted to meet these requirements. There is only one solution to this problem: improve the conversion ratio of the nuclear system and quickly reach the breeding; this would lead to the reduction of the natural uranium consumption by a factor of about 50. However, this condition is not sufficient; the commercial breeder must have a breeding gain as high as possible because the Pu out-of-pile time and the Pu losses in the cycle could lead to an unacceptable doubling time for the system, if the breeding gain is too low. That is the reason why it is vital to develop high performance breeder reactors. The present paper indicates how the Gas-cooled Breeder Reactor [GBR] can meet the problems mentioned above, on the basis of recent and realistic studies. It briefly describes the present status of GBR development, from the predecessors in the gas cooled reactor line, particularly the AGR. It shows how the GBR fuel takes mostly profit from the LMFBR fuel irradiation experience. It compares the GBR performance on a consistent basis with that of the LMFBR. The GBR capital and fuel cycle costs are compared with those of thermal and fast reactors respectively. The conclusion is, based on a cost-benefit study, that the GBR must be quickly developed in order

  7. High performance nano-composite technology development

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Whung Whoe; Rhee, C. K.; Kim, S. J.; Park, S. D. [KAERI, Taejon (Korea, Republic of); Kim, E. K.; Jung, S. Y.; Ryu, H. J. [KRICT, Taejon (Korea, Republic of); Hwang, S. S.; Kim, J. K.; Hong, S. M. [KIST, Taejon (Korea, Republic of); Chea, Y. B. [KIGAM, Taejon (Korea, Republic of); Choi, C. H.; Kim, S. D. [ATS, Taejon (Korea, Republic of); Cho, B. G.; Lee, S. H. [HGREC, Taejon (Korea, Republic of)

    1999-06-15

    The trend of new material development are being to carried out not only high performance but also environmental attraction. Especially nano composite material which enhances the functional properties of components, extending the component life resulting to reduced the wastes and environmental contamination, has a great effect on various industrial area. The application of nano composite, depends on the polymer matrix and filler materials, has various application from semiconductor to medical field. In spite of nano composite merits, nano composite study are confined to a few special materials as a lab, scale because a few technical difficulties are still on hold. Therefore, the purpose of this study establishes the systematical planning to carried out the next generation projects on order to compete with other countries and overcome the protective policy of advanced countries with grasping over sea's development trends and our present status. (author).

  8. How to create high-performing teams.

    Science.gov (United States)

    Lam, Samuel M

    2010-02-01

    This article is intended to discuss inspirational aspects on how to lead a high-performance team. Cogent topics discussed include how to hire staff through methods of "topgrading" with reference to Geoff Smart and "getting the right people on the bus" referencing Jim Collins' work. In addition, once the staff is hired, this article covers how to separate the "eagles from the ducks" and how to inspire one's staff by creating the right culture with suggestions for further reading by Don Miguel Ruiz (The four agreements) and John Maxwell (21 Irrefutable laws of leadership). In addition, Simon Sinek's concept of "Start with Why" is elaborated to help a leader know what the core element should be with any superior culture. Thieme Medical Publishers.

  9. High performance nano-composite technology development

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Whung Whoe; Rhee, C. K.; Kim, S. J.; Park, S. D. [KAERI, Taejon (Korea, Republic of); Kim, E. K.; Jung, S. Y.; Ryu, H. J. [KRICT, Taejon (Korea, Republic of); Hwang, S. S.; Kim, J. K.; Hong, S. M. [KIST, Taejon (Korea, Republic of); Chea, Y. B. [KIGAM, Taejon (Korea, Republic of); Choi, C. H.; Kim, S. D. [ATS, Taejon (Korea, Republic of); Cho, B. G.; Lee, S. H. [HGREC, Taejon (Korea, Republic of)

    1999-06-15

    The trend of new material development are being to carried out not only high performance but also environmental attraction. Especially nano composite material which enhances the functional properties of components, extending the component life resulting to reduced the wastes and environmental contamination, has a great effect on various industrial area. The application of nano composite, depends on the polymer matrix and filler materials, has various application from semiconductor to medical field. In spite of nano composite merits, nano composite study are confined to a few special materials as a lab, scale because a few technical difficulties are still on hold. Therefore, the purpose of this study establishes the systematical planning to carried out the next generation projects on order to compete with other countries and overcome the protective policy of advanced countries with grasping over sea's development trends and our present status. (author).

  10. High performance nano-composite technology development

    International Nuclear Information System (INIS)

    Kim, Whung Whoe; Rhee, C. K.; Kim, S. J.; Park, S. D.; Kim, E. K.; Jung, S. Y.; Ryu, H. J.; Hwang, S. S.; Kim, J. K.; Hong, S. M.; Chea, Y. B.; Choi, C. H.; Kim, S. D.; Cho, B. G.; Lee, S. H.

    1999-06-01

    The trend of new material development are being to carried out not only high performance but also environmental attraction. Especially nano composite material which enhances the functional properties of components, extending the component life resulting to reduced the wastes and environmental contamination, has a great effect on various industrial area. The application of nano composite, depends on the polymer matrix and filler materials, has various application from semiconductor to medical field. In spite of nano composite merits, nano composite study are confined to a few special materials as a lab, scale because a few technical difficulties are still on hold. Therefore, the purpose of this study establishes the systematical planning to carried out the next generation projects on order to compete with other countries and overcome the protective policy of advanced countries with grasping over sea's development trends and our present status. (author).

  11. High Performance with Prescriptive Optimization and Debugging

    DEFF Research Database (Denmark)

    Jensen, Nicklas Bo

    parallelization and automatic vectorization is attractive as it transparently optimizes programs. The thesis contributes an improved dependence analysis for explicitly parallel programs. These improvements lead to more loops being vectorized, on average we achieve a speedup of 1.46 over the existing dependence...... analysis and vectorizer in GCC. Automatic optimizations often fail for theoretical and practical reasons. When they fail we argue that a hybrid approach can be effective. Using compiler feedback, we propose to use the programmer’s intuition and insight to achieve high performance. Compiler feedback...... enlightens the programmer why a given optimization was not applied, and suggest how to change the source code to make it more amenable to optimizations. We show how this can yield significant speedups and achieve 2.4 faster execution on a real industrial use case. To aid in parallel debugging we propose...

  12. Optimizing High Performance Self Compacting Concrete

    Directory of Open Access Journals (Sweden)

    Raymond A Yonathan

    2017-01-01

    Full Text Available This paper’s objectives are to learn the effect of glass powder, silica fume, Polycarboxylate Ether, and gravel to optimizing composition of each factor in making High Performance SCC. Taguchi method is proposed in this paper as best solution to minimize specimen variable which is more than 80 variations. Taguchi data analysis method is applied to provide composition, optimizing, and the effect of contributing materials for nine variable of specimens. Concrete’s workability was analyzed using Slump flow test, V-funnel test, and L-box test. Compressive and porosity test were performed for the hardened state. With a dimension of 100×200 mm the cylindrical specimens were cast for compressive test with the age of 3, 7, 14, 21, 28 days. Porosity test was conducted at 28 days. It is revealed that silica fume contributes greatly to slump flow and porosity. Coarse aggregate shows the greatest contributing factor to L-box and compressive test. However, all factors show unclear result to V-funnel test.

  13. Development of a screening tool for detecting undernutrition and dietary inadequacy among rural elderly in Malaysia: simple indices to identify individuals at high risk.

    Science.gov (United States)

    Shahar, S; Dixon, R A; Earland, J

    1999-11-01

    Undernutrition and the consumption of poor diets are prevalent among elderly people in developing countries. Recognising the importance of the early identification of individuals at high nutritional risk, this study aimed to develop a simple tool for screening. A cross-sectional study was conducted on 11 randomly selected villages among the 62 in Mersing District, Malaysia. Undernutrition was assessed using body mass index, plasma albumin and haemoglobin on 285 subjects. Dietary inadequacy (a count of nutrients falling below two-thirds of the Recommended Dietary Allowances) was examined for 337 subjects. Logistic regression analysis was performed to identify significant predictors of undernutrition and dietary inadequacy from social and health factors, and to derive appropriate indices based on these predictions. The multivariate predictors of undernutrition were 'no joint disease', 'smoker', 'no hypertension', 'depended on others for economic resource', 'respiratory disease', 'perceived weight loss' and 'chewing difficulty', with a joint sensitivity of 56% and specificity of 84%. The equivalent predictors of dietary inadequacy were 'unable to take public transport', 'loss of appetite', 'chewing difficulty', 'no regular fruit intake' and 'regularly taking less than three meals per day', with a joint sensitivity of 77% and specificity of 47%. These predictions, with minor modification to simplify operational use, led to the production of a simple screening tool. The tool can be used by public health professionals or community workers or leaders as a simple and rapid instrument to screen individual at high risk of undernutrition and/or dietary inadequacy.

  14. EXTRACTION AND QUANTITATIVE ANALYSIS OF ELEMENTAL SULFUR FROM SULFIDE MINERAL SURFACES BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY. (R826189)

    Science.gov (United States)

    A simple method for the quantitative determination of elemental sulfur on oxidized sulfide minerals is described. Extraction of elemental sulfur in perchloroethylene and subsequent analysis with high-performance liquid chromatography were used to ascertain the total elemental ...

  15. IMPLEMENTATION OF SIMPLE ADDITIVE WEIGHTING (SAW) METHODE IN DETERMINING HIGH SCHOOL STUDENT’S INTEREST

    OpenAIRE

    Prind Triajeng Pungkasanti

    2017-01-01

    The Ministry of Research, Technology, and Higher Education of Republic of Indonesia has set a regulation about curriculum applied in education field named Kurikulum 2013. One of the subsections in the Kurikulum 2013 regulates all requirements of majoring in high school. High school students determine their major based on Kurrikulum 2013 as they are on the 10th grade. The purpose of the majoring in education is to allow children development based on their skills and interests, because before, ...

  16. Designing 3D highly ordered nanoporous CuO electrodes for high-performance asymmetric supercapacitors.

    Science.gov (United States)

    Moosavifard, Seyyed E; El-Kady, Maher F; Rahmanifar, Mohammad S; Kaner, Richard B; Mousavi, Mir F

    2015-03-04

    The increasing demand for energy has triggered tremendous research efforts for the development of lightweight and durable energy storage devices. Herein, we report a simple, yet effective, strategy for high-performance supercapacitors by building three-dimensional pseudocapacitive CuO frameworks with highly ordered and interconnected bimodal nanopores, nanosized walls (∼4 nm) and large specific surface area of 149 m(2) g(-1). This interesting electrode structure plays a key role in providing facilitated ion transport, short ion and electron diffusion pathways and more active sites for electrochemical reactions. This electrode demonstrates excellent electrochemical performance with a specific capacitance of 431 F g(-1) (1.51 F cm(-2)) at 3.5 mA cm(-2) and retains over 70% of this capacitance when operated at an ultrafast rate of 70 mA cm(-2). When this highly ordered CuO electrode is assembled in an asymmetric cell with an activated carbon electrode, the as-fabricated device demonstrates remarkable performance with an energy density of 19.7 W h kg(-1), power density of 7 kW kg(-1), and excellent cycle life. This work presents a new platform for high-performance asymmetric supercapacitors for the next generation of portable electronics and electric vehicles.

  17. High Performance Circularly Polarized Microstrip Antenna

    Science.gov (United States)

    Bondyopadhyay, Probir K. (Inventor)

    1997-01-01

    A microstrip antenna for radiating circularly polarized electromagnetic waves comprising a cluster array of at least four microstrip radiator elements, each of which is provided with dual orthogonal coplanar feeds in phase quadrature relation achieved by connection to an asymmetric T-junction power divider impedance notched at resonance. The dual fed circularly polarized reference element is positioned with its axis at a 45 deg angle with respect to the unit cell axis. The other three dual fed elements in the unit cell are positioned and fed with a coplanar feed structure with sequential rotation and phasing to enhance the axial ratio and impedance matching performance over a wide bandwidth. The centers of the radiator elements are disposed at the corners of a square with each side of a length d in the range of 0.7 to 0.9 times the free space wavelength of the antenna radiation and the radiator elements reside in a square unit cell area of sides equal to 2d and thereby permit the array to be used as a phased array antenna for electronic scanning and is realizable in a high temperature superconducting thin film material for high efficiency.

  18. NCI's Transdisciplinary High Performance Scientific Data Platform

    Science.gov (United States)

    Evans, Ben; Antony, Joseph; Bastrakova, Irina; Car, Nicholas; Cox, Simon; Druken, Kelsey; Evans, Bradley; Fraser, Ryan; Ip, Alex; Kemp, Carina; King, Edward; Minchin, Stuart; Larraondo, Pablo; Pugh, Tim; Richards, Clare; Santana, Fabiana; Smillie, Jon; Trenham, Claire; Wang, Jingbo; Wyborn, Lesley

    2016-04-01

    The Australian National Computational Infrastructure (NCI) manages Earth Systems data collections sourced from several domains and organisations onto a single High Performance Data (HPD) Node to further Australia's national priority research and innovation agenda. The NCI HPD Node has rapidly established its value, currently managing over 10 PBytes of datasets from collections that span a wide range of disciplines including climate, weather, environment, geoscience, geophysics, water resources and social sciences. Importantly, in order to facilitate broad user uptake, maximise reuse and enable transdisciplinary access through software and standardised interfaces, the datasets, associated information systems and processes have been incorporated into the design and operation of a unified platform that NCI has called, the National Environmental Research Data Interoperability Platform (NERDIP). The key goal of the NERDIP is to regularise data access so that it is easily discoverable, interoperable for different domains and enabled for high performance methods. It adopts and implements international standards and data conventions, and promotes scientific integrity within a high performance computing and data analysis environment. NCI has established a rich and flexible computing environment to access to this data, through the NCI supercomputer; a private cloud that supports both domain focused virtual laboratories and in-common interactive analysis interfaces; as well as remotely through scalable data services. Data collections of this importance must be managed with careful consideration of both their current use and the needs of the end-communities, as well as its future potential use, such as transitioning to more advanced software and improved methods. It is therefore critical that the data platform is both well-managed and trusted for stable production use (including transparency and reproducibility), agile enough to incorporate new technological advances and

  19. Silicon Photomultiplier Performance in High ELectric Field

    Science.gov (United States)

    Montoya, J.; Morad, J.

    2016-12-01

    Roughly 27% of the universe is thought to be composed of dark matter. The Large Underground Xenon (LUX) relies on the emission of light from xenon atoms after a collision with a dark matter particle. After a particle interaction in the detector, two things can happen: the xenon will emit light and charge. The charge (electrons), in the liquid xenon needs to be pulled into the gas section so that it can interact with gas and emit light. This allows LUX to convert a single electron into many photons. This is done by applying a high voltage across the liquid and gas regions, effectively ripping electrons out of the liquid xenon and into the gas. The current device used to detect photons is the photomultiplier tube (PMT). These devices are large and costly. In recent years, a new technology that is capable of detecting single photons has emerged, the silicon photomultiplier (SiPM). These devices are cheaper and smaller than PMTs. Their performance in a high electric fields, such as those found in LUX, are unknown. It is possible that a large electric field could introduce noise on the SiPM signal, drowning the single photon detection capability. My hypothesis is that SiPMs will not observe a significant increase is noise at an electric field of roughly 10kV/cm (an electric field within the range used in detectors like LUX). I plan to test this hypothesis by first rotating the SiPMs with no applied electric field between two metal plates roughly 2 cm apart, providing a control data set. Then using the same angles test the dark counts with the constant electric field applied. Possibly the most important aspect of LUX, is the photon detector because it's what detects the signals. Dark matter is detected in the experiment by looking at the ratio of photons to electrons emitted for a given interaction in the detector. Interactions with a low electron to photon ratio are more like to be dark matter events than those with a high electron to photon ratio. The ability to

  20. Soft Functional Silicone Elastomers with High Dielectric Permittivty: Simple Additives vs. Cross-Linked Synthesized Copolymers

    DEFF Research Database (Denmark)

    Madsen, Frederikke Bahrt; Yu, Liyun; Skov, Anne Ladegaard

    Though dielectric elastomers (DEs) have many favorable properties, the issue of high driving voltages limits the commercial viability of the technology. Improved actuation at lower voltages can be obtained by decreasing the Young’s modulus and/or decreasing the dielectric permittivity of the elas......Though dielectric elastomers (DEs) have many favorable properties, the issue of high driving voltages limits the commercial viability of the technology. Improved actuation at lower voltages can be obtained by decreasing the Young’s modulus and/or decreasing the dielectric permittivity...... of the elastomer. A decrease in Young’s modulus, however, is often accompanied by the loss of mechanical stability and thereby the lifetime of the DE whereas addition of high permittivity fillers such as metal oxides often increases Young’s modulus such that improved actuation is not accomplished. New soft...... silicone elastomers with high dielectric permittivity were prepared through the use of chloropropyl-functional silicones. One method was through the synthesis of modular cross-linkable chloropropyl-functional copolymers that allow for a high degree of chemical freedom such that a tuneable silicone...

  1. Junior High School Students’ Perception about Simple Environmental Problem as an Impact of Problem based Learning

    Science.gov (United States)

    Tapilouw, M. C.; Firman, H.; Redjeki, S.; Chandra, D. T.

    2017-09-01

    Environmental problem is a real problem that occur in student’s daily life. Junior high school students’ perception about environmental problem is interesting to be investigated. The major aim of this study is to explore junior high school students’ perception about environmental problems around them and ways to solve the problem. The subject of this study is 69 Junior High School Students from two Junior High School in Bandung. This study use two open ended question. The core of first question is environmental problem around them (near school or house). The core of second question is the way to prevent or to solve the problem. These two question are as an impact of problem based learning in science learning. There are two major findings in this study. The first finding, based on most students’ perception, plastic waste cause an environmental problem. The second finding, environmental awareness can be a solution to prevent environmental pollution. The third finding, most student can classify environmental pollution into land, water and air pollution. We can conclude that Junior High School Students see the environmental problem as a phenomenon and teacher can explore environmental problem to guide the way of preventing and resolving environmental problem.

  2. The Role of Performance Management in the High Performance Organisation

    NARCIS (Netherlands)

    de Waal, André A.; van der Heijden, Beatrice I.J.M.

    2014-01-01

    The allegiance of partnering organisations and their employees to an Extended Enterprise performance is its proverbial sword of Damocles. Literature on Extended Enterprises focuses on collaboration, inter-organizational integration and learning to avoid diminishing or missing allegiance becoming an

  3. A SIMPLE ANALYSIS OF THE PROPAGATING ACOUSTOELECTRIC HIGH-FIELD DOMAIN

    DEFF Research Database (Denmark)

    Mosekilde, Erik

    1968-01-01

    An analytical treatment of the uniformly propagating acoustoelectric high-field domain is presented in the limit of zero diffusion. Expressions for the electron density and the acoustic energy density as functions of the electric field are given. The domain velocity is determined. ©1968 The Ameri......An analytical treatment of the uniformly propagating acoustoelectric high-field domain is presented in the limit of zero diffusion. Expressions for the electron density and the acoustic energy density as functions of the electric field are given. The domain velocity is determined. ©1968...

  4. Simple syntheses of 3-substituted indoles and their application for high yield 14C-labelling

    International Nuclear Information System (INIS)

    Schallenberg, J.; Meyer, E.

    1983-01-01

    Methods are described which allow the synthesis of several plant indole alkaloids and their metabolites at different scales. Compounds synthesized include gramine (1) (3-dimethylaminomethylindole) which is directly derived from indole, while its biosynthetic precursors 3-aminomethylindole (3) and 3-methylaminomethylindole (2) as well as indole3-carboxylic acid (7) are synthesized via indole-3-aldehyde (6). Slight changes of the experimental conditions allow syntheses with high yields not only at the molar but also at the μmolar level. This is extremely useful when isotope labelled compounds of high specific radioactivity are required for studies of plant metabolism. (orig.)

  5. Tobacco Stem-Based Activated Carbons for High Performance Supercapacitors

    Science.gov (United States)

    Xia, Xiaohong; Liu, Hongbo; Shi, Lei; He, Yuede

    2012-09-01

    Tobacco stem-based activated carbons (TS-ACs) were prepared by simple KOH activation and their application as electrodes in the electrical double layer capacitor (EDLC) performed successfully. The BET surface area, pore volume, and pore size distribution of the TS-ACs were evaluated based on N2 adsorption isotherms at 77 K. The surface area of the obtained activated carbons varies over a wide range (1472.8-3326.7 m2/g) and the mesoporosity was enhanced significantly as the ratio of KOH to tobacco stem (TS) increased. The electrochemical behaviors of series TS-ACs were characterized by means of galvanostatic charging/discharging, cyclic voltammetry, and impedance spectroscopy. The correlation between electrochemical properties and pore structure was investigated. A high specific capacitance value as 190 F/g at 1 mA/cm2 was obtained in 1 M LiPF6-EC/DMC/DEC electrolyte solution. Furthermore, good performance is also achieved even at high current densities. A development of new use for TS into a valuable energy storage material is explored.

  6. When Langmuir is too simple: H-2 dissociation on Pd(111) at high coverage

    DEFF Research Database (Denmark)

    Lopez, Nuria; Lodziana, Zbigniew; Illas, F.

    2004-01-01

    Recent experiments of H-2 adsorption on Pd(111) [T. Mitsui et al., Nature (London) 422, 705 (2003)] have questioned the classical Langmuir picture of second order adsorption kinetics at high surface coverage requiring pairs of empty sites for the dissociative chemisorption. Experiments find that ...

  7. High-concentration boron doping of graphene nanoplatelets by simple thermal annealing and their supercapacitive properties

    Science.gov (United States)

    Yeom, Da-Young; Jeon, Woojin; Tu, Nguyen Dien Kha; Yeo, So Young; Lee, Sang-Soo; Sung, Bong June; Chang, Hyejung; Lim, Jung Ah; Kim, Heesuk

    2015-05-01

    For the utilization of graphene in various energy storage and conversion applications, it must be synthesized in bulk with reliable and controllable electrical properties. Although nitrogen-doped graphene shows a high doping efficiency, its electrical properties can be easily affected by oxygen and water impurities from the environment. We here report that boron-doped graphene nanoplatelets with desirable electrical properties can be prepared by the simultaneous reduction and boron-doping of graphene oxide (GO) at a high annealing temperature. B-doped graphene nanoplatelets prepared at 1000 °C show a maximum boron concentration of 6.04 ± 1.44 at %, which is the highest value among B-doped graphenes prepared using various methods. With well-mixed GO and g-B2O3 as the dopant, highly uniform doping is achieved for potentially gram-scale production. In addition, as a proof-of-concept, highly B-doped graphene nanoplatelets were used as an electrode of an electrochemical double-layer capacitor (EDLC) and showed an excellent specific capacitance value of 448 F/g in an aqueous electrolyte without additional conductive additives. We believe that B-doped graphene nanoplatelets can also be used in other applications such as electrocatalyst and nano-electronics because of their reliable and controllable electrical properties regardless of the outer environment.

  8. A simple method to fabricate electrochemical sensor systems with predictable high-redox amplification

    NARCIS (Netherlands)

    Straver, M.G.; Odijk, Mathieu; Olthuis, Wouter; van den Berg, Albert

    2012-01-01

    In this paper an easy to fabricate SU8/glass-based microfluidic sensor is described with two closely spaced parallel electrodes for highly selective measurements using the redox cycling effect. By varying the length of the microfluidic entrance channel, a diffusion barrier is created for non-cycling

  9. A Simple Test Tube-Based ELISA Experiment for the High-School Classroom

    Science.gov (United States)

    Brokaw, Ann; Cobb, Brian A.

    2009-01-01

    Immunology is gaining prominence both in the media as well as on the Advanced Placement (AP) exam in Biology. One of the challenges of teaching modern biological topics such as immunology and biochemistry in the high-school setting is the increased reliance on expensive technology in the research world. To begin to bridge this widening gap, we…

  10. Multisymplectic Structure-Preserving in Simple Finite Element Method in High Dimensional Case

    Institute of Scientific and Technical Information of China (English)

    BAIYong-Qiang; LIUZhen; PEIMing; ZHENGZhu-Jun

    2003-01-01

    In this paper, we study a finite element scheme of some semi-linear elliptic boundary value problems in high-dhnensjonal space. With uniform mesh, we find that, the numerical scheme derived from finite element method can keep a preserved multisymplectic structure.

  11. High-concentration boron doping of graphene nanoplatelets by simple thermal annealing and their supercapacitive properties.

    Science.gov (United States)

    Yeom, Da-Young; Jeon, Woojin; Tu, Nguyen Dien Kha; Yeo, So Young; Lee, Sang-Soo; Sung, Bong June; Chang, Hyejung; Lim, Jung Ah; Kim, Heesuk

    2015-05-05

    For the utilization of graphene in various energy storage and conversion applications, it must be synthesized in bulk with reliable and controllable electrical properties. Although nitrogen-doped graphene shows a high doping efficiency, its electrical properties can be easily affected by oxygen and water impurities from the environment. We here report that boron-doped graphene nanoplatelets with desirable electrical properties can be prepared by the simultaneous reduction and boron-doping of graphene oxide (GO) at a high annealing temperature. B-doped graphene nanoplatelets prepared at 1000 °C show a maximum boron concentration of 6.04 ± 1.44 at %, which is the highest value among B-doped graphenes prepared using various methods. With well-mixed GO and g-B2O3 as the dopant, highly uniform doping is achieved for potentially gram-scale production. In addition, as a proof-of-concept, highly B-doped graphene nanoplatelets were used as an electrode of an electrochemical double-layer capacitor (EDLC) and showed an excellent specific capacitance value of 448 F/g in an aqueous electrolyte without additional conductive additives. We believe that B-doped graphene nanoplatelets can also be used in other applications such as electrocatalyst and nano-electronics because of their reliable and controllable electrical properties regardless of the outer environment.

  12. Evaluation of Simple and Inexpensive High-Throughput Methods for Phytic Acid Determination

    DEFF Research Database (Denmark)

    Raboy, Victor; Johnson, Amy; Bilyeu, Kristin

    2017-01-01

    High-throughput/low-cost/low-tech methods for phytic acid determination that are sufficiently accurate and reproducible would be of value in plant genetics, crop breeding and in the food and feed industries. Variants of two candidate methods, those described by Vaintraub and Lapteva (Anal Biochem...... and legume flours regardless of endogenous phytic acid levels or matrix constituents....

  13. Structure and properties of simple molecular systems at very high density

    International Nuclear Information System (INIS)

    LeSar, R.

    1989-01-01

    The use of computer simulations in the study of molecular systems at very high density is reviewed. Applications to the thermodynamics of dense fluid nitrogen and phase transitions in solid oxygen are presented. The effects of changes in the atomic electronic structure on the equation of state of very dense helium are discussed. 19 refs., 2 figs

  14. A phenomenological model for the structure-composition relationship of the high Tc cuprates based on simple chemical principles

    International Nuclear Information System (INIS)

    Alarco, J.A.; Talbot, P.C.

    2012-01-01

    A simple phenomenological model for the relationship between structure and composition of the high Tc cuprates is presented. The model is based on two simple crystal chemistry principles: unit cell doping and charge balance within unit cells. These principles are inspired by key experimental observations of how the materials accommodate large deviations from stoichiometry. Consistent explanations for significant HTSC properties can be explained without any additional assumptions while retaining valuable insight for geometric interpretation. Combining these two chemical principles with a review of Crystal Field Theory (CFT) or Ligand Field Theory (LFT), it becomes clear that the two oxidation states in the conduction planes (typically d 8 and d 9 ) belong to the most strongly divergent d-levels as a function of deformation from regular octahedral coordination. This observation offers a link to a range of coupling effects relating vibrations and spin waves through application of Hund’s rules. An indication of this model’s capacity to predict physical properties for HTSC is provided and will be elaborated in subsequent publications. Simple criteria for the relationship between structure and composition in HTSC systems may guide chemical syntheses within new material systems.

  15. A simple approach for producing highly efficient DNA carriers with reduced toxicity based on modified polyallylamine

    Energy Technology Data Exchange (ETDEWEB)

    Oskuee, Reza Kazemi [Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of); Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of); Dosti, Fatemeh [School of Pharmacy, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of); Gholami, Leila [Targeted Drug Delivery Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of); Malaekeh-Nikouei, Bizhan, E-mail: malaekehb@mums.ac.ir [Nanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of)

    2015-04-01

    Nowadays gene delivery is a topic in many research studies. Non-viral vectors have many advantages over viral vectors in terms of safety, immunogenicity and gene carrying capacity but they suffer from low transfection efficiency and high toxicity. In this study, polyallylamine (PAA), the cationic polymer, has been modified with hydrophobic branches to increase the transfection efficiency of the polymer. Polyallylamine with molecular weights of 15 and 65 kDa was selected and grafted with butyl, hexyl and decyl acrylate at percentages of 10, 30 and 50. The ability of the modified polymer to condense DNA was examined by ethidium bromide test. The complex of modified polymer and DNA (polyplex) was characterized for size, zeta potential, transfection efficiency and cytotoxicity in Neuro2A cell lines. The results of ethidium bromide test showed that grafting of PAA decreased its ability for DNA condensation but vectors could still condense DNA at moderate and high carrier to DNA ratios. Most of polyplexes had particle size between 150 and 250 nm. The prepared vectors mainly showed positive zeta potential but carriers composed of PAA with high percentage of grafting had negative zeta potential. The best transfection activity was observed in vectors with hexyl acrylate chain. Grafting of polymer reduced its cytotoxicity especially at percentages of 30 and 50. The vectors based of PAA 15 kDa had better transfection efficiency than the vectors made of PAA 65 kDa. In conclusion, results of the present study indicated that grafting PAA 15 kDa with high percentages of hexyl acrylate can help to prepare vectors with better transfection efficiency and less cytotoxicity. - Highlights: • The modified polyallylamine was synthesized as a gene carrier. • Modification of polyallylamine (15 kDa) with high percentages of hexyl acrylate improved transfection activity remarkably. • Grafting of polymer with acrylate derivatives reduced polymer cytotoxicity especially at percentages of

  16. Rule induction performance in amnestic mild cognitive impairment and Alzheimer's dementia: examining the role of simple and biconditional rule learning processes.

    Science.gov (United States)

    Oosterman, Joukje M; Heringa, Sophie M; Kessels, Roy P C; Biessels, Geert Jan; Koek, Huiberdina L; Maes, Joseph H R; van den Berg, Esther

    2017-04-01

    Rule induction tests such as the Wisconsin Card Sorting Test require executive control processes, but also the learning and memorization of simple stimulus-response rules. In this study, we examined the contribution of diminished learning and memorization of simple rules to complex rule induction test performance in patients with amnestic mild cognitive impairment (aMCI) or Alzheimer's dementia (AD). Twenty-six aMCI patients, 39 AD patients, and 32 control participants were included. A task was used in which the memory load and the complexity of the rules were independently manipulated. This task consisted of three conditions: a simple two-rule learning condition (Condition 1), a simple four-rule learning condition (inducing an increase in memory load, Condition 2), and a complex biconditional four-rule learning condition-inducing an increase in complexity and, hence, executive control load (Condition 3). Performance of AD patients declined disproportionately when the number of simple rules that had to be memorized increased (from Condition 1 to 2). An additional increment in complexity (from Condition 2 to 3) did not, however, disproportionately affect performance of the patients. Performance of the aMCI patients did not differ from that of the control participants. In the patient group, correlation analysis showed that memory performance correlated with Condition 1 performance, whereas executive task performance correlated with Condition 2 performance. These results indicate that the reduced learning and memorization of underlying task rules explains a significant part of the diminished complex rule induction performance commonly reported in AD, although results from the correlation analysis suggest involvement of executive control functions as well. Taken together, these findings suggest that care is needed when interpreting rule induction task performance in terms of executive function deficits in these patients.

  17. Evaluating performance of high efficiency mist eliminators

    Energy Technology Data Exchange (ETDEWEB)

    Waggoner, Charles A.; Parsons, Michael S.; Giffin, Paxton K. [Mississippi State University, Institute for Clean Energy Technology, 205 Research Blvd, Starkville, MS (United States)

    2013-07-01

    Processing liquid wastes frequently generates off gas streams with high humidity and liquid aerosols. Droplet laden air streams can be produced from tank mixing or sparging and processes such as reforming or evaporative volume reduction. Unfortunately these wet air streams represent a genuine threat to HEPA filters. High efficiency mist eliminators (HEME) are one option for removal of liquid aerosols with high dissolved or suspended solids content. HEMEs have been used extensively in industrial applications, however they have not seen widespread use in the nuclear industry. Filtering efficiency data along with loading curves are not readily available for these units and data that exist are not easily translated to operational parameters in liquid waste treatment plants. A specialized test stand has been developed to evaluate the performance of HEME elements under use conditions of a US DOE facility. HEME elements were tested at three volumetric flow rates using aerosols produced from an iron-rich waste surrogate. The challenge aerosol included submicron particles produced from Laskin nozzles and super micron particles produced from a hollow cone spray nozzle. Test conditions included ambient temperature and relative humidities greater than 95%. Data collected during testing HEME elements from three different manufacturers included volumetric flow rate, differential temperature across the filter housing, downstream relative humidity, and differential pressure (dP) across the filter element. Filter challenge was discontinued at three intermediate dPs and the filter to allow determining filter efficiency using dioctyl phthalate and then with dry surrogate aerosols. Filtering efficiencies of the clean HEME, the clean HEME loaded with water, and the HEME at maximum dP were also collected using the two test aerosols. Results of the testing included differential pressure vs. time loading curves for the nine elements tested along with the mass of moisture and solid

  18. An integrated framework for high level design of high performance signal processing circuits on FPGAs

    Science.gov (United States)

    Benkrid, K.; Belkacemi, S.; Sukhsawas, S.

    2005-06-01

    This paper proposes an integrated framework for the high level design of high performance signal processing algorithms' implementations on FPGAs. The framework emerged from a constant need to rapidly implement increasingly complicated algorithms on FPGAs while maintaining the high performance needed in many real time digital signal processing applications. This is particularly important for application developers who often rely on iterative and interactive development methodologies. The central idea behind the proposed framework is to dynamically integrate high performance structural hardware description languages with higher level hardware languages in other to help satisfy the dual requirement of high level design and high performance implementation. The paper illustrates this by integrating two environments: Celoxica's Handel-C language, and HIDE, a structural hardware environment developed at the Queen's University of Belfast. On the one hand, Handel-C has been proven to be very useful in the rapid design and prototyping of FPGA circuits, especially control intensive ones. On the other hand, HIDE, has been used extensively, and successfully, in the generation of highly optimised parameterisable FPGA cores. In this paper, this is illustrated in the construction of a scalable and fully parameterisable core for image algebra's five core neighbourhood operations, where fully floorplanned efficient FPGA configurations, in the form of EDIF netlists, are generated automatically for instances of the core. In the proposed combined framework, highly optimised data paths are invoked dynamically from within Handel-C, and are synthesized using HIDE. Although the idea might seem simple prima facie, it could have serious implications on the design of future generations of hardware description languages.

  19. A simple, high-yield, apparatus for NEG coating of vacuum beamline elements

    International Nuclear Information System (INIS)

    Ron, G; Oort, R; Lee, D

    2010-01-01

    Non-Evaporable Getter (NEG) materials are extremely useful in vacuum systems for achieving Ultra High Vacuum. Recently, these materials have been used to coat the inner surfaces of vacuum components, acting as an internal, passive, vacuum pump. We have constructed a low cost apparatus, which allows coating of very small diameter vacuum tubes, used as differential pumping stages. Despite the relative ease of construction, we are routinely able to achieve high coating yields. We further describe an improvement to our system, which is able to achieve the same yield, at an even lower complexity by using an easily manufactured permanent magnet arrangement. The designs described are extendible to virtually any combination of length and diameter of the components to be coated.

  20. A simple method for reducing inevitable dielectric loss in high-permittivity dielectric elastomers

    DEFF Research Database (Denmark)

    Madsen, Frederikke Bahrt; Yu, Liyun; Mazurek, Piotr Stanislaw

    2016-01-01

    elastomer matrix, with high dielectric permittivity and a low Young's modulus, aligned with no loss of mechanical stability, was prepared through the use of commercially available chloropropyl-functional silicone oil mixed into a tough commercial liquid silicone rubber silicone elastomer. The addition...... also decreased the dielectric losses of an elastomer containing dielectric permittivity-enhancing TiO2 fillers. Commercially available chloropropyl-functional silicone oil thus constitutes a facile method for improved silicone DEs, with very low dielectric losses.......Commercial viability of dielectric elastomers (DEs) is currently limited by a few obstacles, including high driving voltages (in the kV range). Driving voltage can be lowered by either decreasing the Young's modulus or increasing the dielectric permittivity of silicone elastomers, or a combination...

  1. Highly-Expressive Spaces of Well-Behaved Transformations: Keeping It Simple

    DEFF Research Database (Denmark)

    Freifeld, Oren; Hauberg, Søren; Batmanghelich, Kayhan

    We propose novel finite-dimensional spaces of Rn → Rn transformations, n ∈ {1, 2, 3}, derived from (continuously-defined) parametric stationary velocity fields. Particularly, we obtain these transformations, which are diffeomorphisms, by fast and highly-accurate integration of continuous piecewise...... transformations). Its applications include, but are not limited to: unconstrained optimization over monotonic functions; modeling cumulative distribution functions or histograms; time warping; image registration; landmark-based warping; real-time diffeomorphic image editing....

  2. Intracerebrally recorded high frequency oscillations: Simple visual assessment versus automated detection

    Czech Academy of Sciences Publication Activity Database

    Pail, M.; Halámek, Josef; Daniel, P.; Kuba, R.; Tyrlíková, I.; Chrastina, J.; Jurák, Pavel; Rektor, I.; Brázdil, M.

    2013-01-01

    Roč. 124, č. 10 (2013), s. 1935-1942 ISSN 1388-2457 R&D Projects: GA ČR GAP103/11/0933; GA MŠk ED0017/01/01 Institutional support: RVO:68081731 Keywords : High frequency oscillations * Spikes * Ripples * Temporal lobe epilepsy * Extratemporal lobe epilepsy * Seizure onset zone * Epileptogenic zone Subject RIV: FH - Neurology Impact factor: 2.979, year: 2013

  3. Static Aeroelastic Effects on High Performance Aircraft

    Science.gov (United States)

    1987-06-01

    davis la rffrence 9. L’avion est instrurnent6, en plus des capteurs classiques des param~tres de n~ca- nique du vol. de plusleurs centaines de jauges de...crites §2.3.5, et lensemble dv l’analyse, pernet- tent le calcul des r~ponues des jauges en fonction dv X soit ar ( X) , lv procesnus de d~rivation...travissonique. Rema rque La smine technique d’identification par rtponne dv jauges s’applique (plus simple- ment) sur len essais en soufflerie, pour la

  4. An integrated high performance Fastbus slave interface

    International Nuclear Information System (INIS)

    Christiansen, J.; Ljuslin, C.

    1993-01-01

    A high performance CMOS Fastbus slave interface ASIC (Application Specific Integrated Circuit) supporting all addressing and data transfer modes defined in the IEEE 960 - 1986 standard is presented. The FAstbus Slave Integrated Circuit (FASIC) is an interface between the asynchronous Fastbus and a clock synchronous processor/memory bus. It can work stand-alone or together with a 32 bit microprocessor. The FASIC is a programmable device enabling its direct use in many different applications. A set of programmable address mapping windows can map Fastbus addresses to convenient memory addresses and at the same time act as address decoding logic. Data rates of 100 MBytes/sec to Fastbus can be obtained using an internal FIFO in the FASIC to buffer data between the two buses during block transfers. Message passing from Fastbus to a microprocessor on the slave module is supported. A compact (70 mm x 170 mm) Fastbus slave piggy back sub-card interface including level conversion between ECL and TTL signal levels has been implemented using surface mount components and the 208 pin FASIC chip

  5. High Performance Graphene Oxide Based Rubber Composites

    Science.gov (United States)

    Mao, Yingyan; Wen, Shipeng; Chen, Yulong; Zhang, Fazhong; Panine, Pierre; Chan, Tung W.; Zhang, Liqun; Liang, Yongri; Liu, Li

    2013-01-01

    In this paper, graphene oxide/styrene-butadiene rubber (GO/SBR) composites with complete exfoliation of GO sheets were prepared by aqueous-phase mixing of GO colloid with SBR latex and a small loading of butadiene-styrene-vinyl-pyridine rubber (VPR) latex, followed by their co-coagulation. During co-coagulation, VPR not only plays a key role in the prevention of aggregation of GO sheets but also acts as an interface-bridge between GO and SBR. The results demonstrated that the mechanical properties of the GO/SBR composite with 2.0 vol.% GO is comparable with those of the SBR composite reinforced with 13.1 vol.% of carbon black (CB), with a low mass density and a good gas barrier ability to boot. The present work also showed that GO-silica/SBR composite exhibited outstanding wear resistance and low-rolling resistance which make GO-silica/SBR very competitive for the green tire application, opening up enormous opportunities to prepare high performance rubber composites for future engineering applications. PMID:23974435

  6. Initial rheological description of high performance concretes

    Directory of Open Access Journals (Sweden)

    Alessandra Lorenzetti de Castro

    2006-12-01

    Full Text Available Concrete is defined as a composite material and, in rheological terms, it can be understood as a concentrated suspension of solid particles (aggregates in a viscous liquid (cement paste. On a macroscopic scale, concrete flows as a liquid. It is known that the rheological behavior of the concrete is close to that of a Bingham fluid and two rheological parameters regarding its description are needed: yield stress and plastic viscosity. The aim of this paper is to present the initial rheological description of high performance concretes using the modified slump test. According to the results, an increase of yield stress was observed over time, while a slight variation in plastic viscosity was noticed. The incorporation of silica fume showed changes in the rheological properties of fresh concrete. The behavior of these materials also varied with the mixing procedure employed in their production. The addition of superplasticizer meant that there was a large reduction in the mixture's yield stress, while plastic viscosity remained practically constant.

  7. High thermoelectric performance of graphite nanofibers.

    Science.gov (United States)

    Tran, Van-Truong; Saint-Martin, Jérôme; Dollfus, Philippe; Volz, Sebastian

    2018-02-22

    Graphite nanofibers (GNFs) have been demonstrated to be a promising material for hydrogen storage and heat management in electronic devices. Here, by means of first-principles and transport simulations, we show that GNFs can also be an excellent material for thermoelectric applications thanks to the interlayer weak van der Waals interaction that induces low thermal conductance and a step-like shape in the electronic transmission with mini-gaps, which are necessary ingredients to achieve high thermoelectric performance. This study unveils that the platelet form of GNFs in which graphite layers are perpendicular to the fiber axis can exhibit outstanding thermoelectric properties with a figure of merit ZT reaching 3.55 in a 0.5 nm diameter fiber and 1.1 in a 1.1 nm diameter one. Interestingly, by introducing 14 C isotope doping, ZT can even be enhanced up to more than 5, and more than 8 if we include the effect of finite phonon mean free path, which demonstrates the amazing thermoelectric potential of GNFs.

  8. Durability of high performance concrete in seawater

    International Nuclear Information System (INIS)

    Amjad Hussain Memon; Salihuddin Radin Sumadi; Rabitah Handan

    2000-01-01

    This paper presents a report on the effects of blended cements on the durability of high performance concrete (HPC) in seawater. In this research the effect of seawater was investigated. The specimens were initially subjected to water curing for seven days inside the laboratory at room temperature, followed by seawater curing exposed to tidal zone until testing. In this study three levels of cement replacement (0%, 30% and 70%) were used. The combined use of chemical and mineral admixtures has resulted in a new generation of concrete called HPC. The HPC has been identified as one of the most important advanced materials necessary in the effort to build a nation's infrastructure. HPC opens new opportunities in the utilization of the industrial by-products (mineral admixtures) in the construction industry. As a matter of fact permeability is considered as one of the fundamental properties governing the durability of concrete in the marine environment. Results of this investigation indicated that the oxygen permeability values for the blended cement concretes at the age of one year are reduced by a factor of about 2 as compared to OPC control mix concrete. Therefore both blended cement concretes are expected to withstand in the seawater exposed to tidal zone without serious deterioration. (Author)

  9. High linearity current communicating passive mixer employing a simple resistor bias

    International Nuclear Information System (INIS)

    Liu Rongjiang; Guo Guiliang; Yan Yuepeng

    2013-01-01

    A high linearity current communicating passive mixer including the mixing cell and transimpedance amplifier (TIA) is introduced. It employs the resistor in the TIA to reduce the source voltage and the gate voltage of the mixing cell. The optimum linearity and the maximum symmetric switching operation are obtained at the same time. The mixer is implemented in a 0.25 μm CMOS process. The test shows that it achieves an input third-order intercept point of 13.32 dBm, conversion gain of 5.52 dB, and a single sideband noise figure of 20 dB. (semiconductor integrated circuits)

  10. A simple highly accurate field-line mapping technique for three-dimensional Monte Carlo modeling of plasma edge transport

    International Nuclear Information System (INIS)

    Feng, Y.; Sardei, F.; Kisslinger, J.

    2005-01-01

    The paper presents a new simple and accurate numerical field-line mapping technique providing a high-quality representation of field lines as required by a Monte Carlo modeling of plasma edge transport in the complex magnetic boundaries of three-dimensional (3D) toroidal fusion devices. Using a toroidal sequence of precomputed 3D finite flux-tube meshes, the method advances field lines through a simple bilinear, forward/backward symmetric interpolation at the interfaces between two adjacent flux tubes. It is a reversible field-line mapping (RFLM) algorithm ensuring a continuous and unique reconstruction of field lines at any point of the 3D boundary. The reversibility property has a strong impact on the efficiency of modeling the highly anisotropic plasma edge transport in general closed or open configurations of arbitrary ergodicity as it avoids artificial cross-field diffusion of the fast parallel transport. For stellarator-symmetric magnetic configurations, which are the standard case for stellarators, the reversibility additionally provides an average cancellation of the radial interpolation errors of field lines circulating around closed magnetic flux surfaces. The RFLM technique has been implemented in the 3D edge transport code EMC3-EIRENE and is used routinely for plasma transport modeling in the boundaries of several low-shear and high-shear stellarators as well as in the boundary of a tokamak with 3D magnetic edge perturbations

  11. Alternative High-Performance Ceramic Waste Forms

    Energy Technology Data Exchange (ETDEWEB)

    Sundaram, S. K. [Alfred Univ., NY (United States)

    2017-02-01

    This final report (M5NU-12-NY-AU # 0202-0410) summarizes the results of the project titled “Alternative High-Performance Ceramic Waste Forms,” funded in FY12 by the Nuclear Energy University Program (NEUP Project # 12-3809) being led by Alfred University in collaboration with Savannah River National Laboratory (SRNL). The overall focus of the project is to advance fundamental understanding of crystalline ceramic waste forms and to demonstrate their viability as alternative waste forms to borosilicate glasses. We processed single- and multiphase hollandite waste forms based on simulated waste streams compositions provided by SRNL based on the advanced fuel cycle initiative (AFCI) aqueous separation process developed in the Fuel Cycle Research and Development (FCR&D). For multiphase simulated waste forms, oxide and carbonate precursors were mixed together via ball milling with deionized water using zirconia media in a polyethylene jar for 2 h. The slurry was dried overnight and then separated from the media. The blended powders were then subjected to melting or spark plasma sintering (SPS) processes. Microstructural evolution and phase assemblages of these samples were studied using x-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersion analysis of x-rays (EDAX), wavelength dispersive spectrometry (WDS), transmission electron spectroscopy (TEM), selective area x-ray diffraction (SAXD), and electron backscatter diffraction (EBSD). These results showed that the processing methods have significant effect on the microstructure and thus the performance of these waste forms. The Ce substitution into zirconolite and pyrochlore materials was investigated using a combination of experimental (in situ XRD and x-ray absorption near edge structure (XANES)) and modeling techniques to study these single phases independently. In zirconolite materials, a transition from the 2M to the 4M polymorph was observed with increasing Ce content. The resulting

  12. High-performance macroporous bulk silicon anodes synthesized by template-free chemical etching

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Byoung Man; Lee, Jung-In; Kim, Hyunjung; Cho, Jaephil; Park, Soojin [Interdisciplinary School of Green Energy, Ulsan National Institute of Science and Technology (UNIST), Ulsan (Korea, Republic of)

    2012-07-15

    Three-dimensional porous silicon particles can be produced via the combination of a galvanic displacement reaction and a metal-assisted chemical etching process. This simple synthetic route can be applied to make high-performance anode materials, including high specific capacity, stable cycling retention, and high rate capability, in lithium-ion batteries. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  13. A simple method for the investigation of the high temperature plasticity of metallic materials

    Energy Technology Data Exchange (ETDEWEB)

    Chinh, N.Q. (Inst. for General Physics, Lorand Eoetvoes Univ., Budapest (Hungary)); Juhasz, A. (Inst. for General Physics, Lorand Eoetvoes Univ., Budapest (Hungary)); Tasnadi, P. (Inst. for General Physics, Lorand Eoetvoes Univ., Budapest (Hungary)); Kovacs, I. (Inst. for General Physics, Lorand Eoetvoes Univ., Budapest (Hungary))

    1993-11-01

    The indentation creep test is a powerful and quick method for the investigation of the high temperature plasticity of various materials. During creep test a small cylindrical punch is pressed at constant loads into the surface of the sample and the penetration depth is registered as a function of testing time. On the basis of the creep curves taken at various temperatures and loads the strain rate sensitivity and the activation energy of the steady-state creep process can be determined. The main advantage of this test is that it needs only a small amount of testing material. In this paper the usefullness of this method illustrated by some results obtained on superplastic and non superplastic Al alloys. The indentation results are compared with tensile data obtained on the same materials. (orig.).

  14. SCREENING FOR SIMPLE MYOPIA AMONG HIGH SCHOOL CHILDREN IN HYDERABAD CITY

    Directory of Open Access Journals (Sweden)

    Vundi Krishna

    2016-03-01

    Full Text Available BACKGROUND Refractive error is one of the most common causes of visual impairment around the world and the second leading cause of treatable blindness. Due to the high magnitude of uncorrected refractive errors, myopia is considered as one of the important public health problems, especially in the urban population in India. It has been given high priority under the National Programme for Control of Blindness. AIM The aim of the present study is to know the prevalence of myopia and assess the degree of myopia among school going children. SETTINGS AND DESIGN Cross-sectional study done for one year. METHODS AND MATERIAL Age group of children 13-15 years, a total of 1600 were included in the study. Refractive error was tested using Snellen’s chart, Pin hole test, Occluder, Retinoscope. Statistical Analysis was done using the Epi Info version 7. RESULTS The prevalence of refractive errors was more in private schools (28.6% than in government schools (23%. It was observed that myopia was the major refractive error (89.8% among total refractive errors, followed by astigmatism (6.1% and hypermetropia (4.1%. In myopic children, both eyes were involved in 71.5%, right eye alone in 16.4%. Only 60% (478 and 98.4% (788 have undergone eye checkups yearly once, 36% and 0.3% didn’t have eye checkups so far in private and government schools respectively. CONCLUSION We conclude that prevalence of refractive errors more in private schools than government schools and myopia is the major among refractive errors. In most of them both the eyes are involved. Bitot’s spots were more in government schools, suggesting the need of vitamin A supplementation.

  15. Intelligent Facades for High Performance Green Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Dyson, Anna [Rensselaer Polytechnic Inst., Troy, NY (United States)

    2017-03-01

    Progress Towards Net-Zero and Net-Positive-Energy Commercial Buildings and Urban Districts Through Intelligent Building Envelope Strategies Previous research and development of intelligent facades systems has been limited in their contribution towards national goals for achieving on-site net zero buildings, because this R&D has failed to couple the many qualitative requirements of building envelopes such as the provision of daylighting, access to exterior views, satisfying aesthetic and cultural characteristics, with the quantitative metrics of energy harvesting, storage and redistribution. To achieve energy self-sufficiency from on-site solar resources, building envelopes can and must address this gamut of concerns simultaneously. With this project, we have undertaken a high-performance building integrated combined-heat and power concentrating photovoltaic system with high temperature thermal capture, storage and transport towards multiple applications (BICPV/T). The critical contribution we are offering with the Integrated Concentrating Solar Façade (ICSF) is conceived to improve daylighting quality for improved health of occupants and mitigate solar heat gain while maximally capturing and transferring onsite solar energy. The ICSF accomplishes this multi-functionality by intercepting only the direct-normal component of solar energy (which is responsible for elevated cooling loads) thereby transforming a previously problematic source of energy into a high quality resource that can be applied to building demands such as heating, cooling, dehumidification, domestic hot water, and possible further augmentation of electrical generation through organic Rankine cycles. With the ICSF technology, our team is addressing the global challenge in transitioning commercial and residential building stock towards on-site clean energy self-sufficiency, by fully integrating innovative environmental control systems strategies within an intelligent and responsively dynamic building

  16. High pressure chemistry of red phosphorus by photo-activated simple molecules

    International Nuclear Information System (INIS)

    Ceppatelli, M; Bini, R; Caporali, M; Peruzzini, M; Fanetti, S

    2014-01-01

    High pressure (HP) is very effective in reducing intermolecular distances and inducing unexpected chemical reactions. In addition the photo-activation of the reactants in HP conditions can lead to very efficient and selective processes. The chemistry of phosphorus is currently based on the white molecular form. The red polymeric allotrope, despite more stable and much less toxic, has not attracted much attention so far. However, switching from the white to the red form would benefit any industrial procedure, especially from an environmental point of view. On the other side, water and ethanol are renewable, environmental friendly and largely available molecules, usable as reactants and photo-activators in HP conditions. Here we report a study on the HP photo-induced reactivity of red phosphorus with water and ethanol, showing the possibility of very efficient and selective processes, leading to molecular hydrogen and valuable phosphorus compounds. The reactions have been studied by means of FTIR and Raman spectroscopy and pressure has been generated using membrane Diamond (DAC) and Sapphire (SAC) anvil cells. HP reactivity has been activated by the two-photon absorption of near-UV wavelengths and occurred in total absence of solvents, catalysts and radical initiators, at room T and mild pressure conditions (0.2–1.5 GPa).

  17. High pressure chemistry of red phosphorus by photo-activated simple molecules

    Science.gov (United States)

    Ceppatelli, M.; Fanetti, S.; Bini, R.; Caporali, M.; Peruzzini, M.

    2014-05-01

    High pressure (HP) is very effective in reducing intermolecular distances and inducing unexpected chemical reactions. In addition the photo-activation of the reactants in HP conditions can lead to very efficient and selective processes. The chemistry of phosphorus is currently based on the white molecular form. The red polymeric allotrope, despite more stable and much less toxic, has not attracted much attention so far. However, switching from the white to the red form would benefit any industrial procedure, especially from an environmental point of view. On the other side, water and ethanol are renewable, environmental friendly and largely available molecules, usable as reactants and photo-activators in HP conditions. Here we report a study on the HP photo-induced reactivity of red phosphorus with water and ethanol, showing the possibility of very efficient and selective processes, leading to molecular hydrogen and valuable phosphorus compounds. The reactions have been studied by means of FTIR and Raman spectroscopy and pressure has been generated using membrane Diamond (DAC) and Sapphire (SAC) anvil cells. HP reactivity has been activated by the two-photon absorption of near-UV wavelengths and occurred in total absence of solvents, catalysts and radical initiators, at room T and mild pressure conditions (0.2-1.5 GPa).

  18. High-performance commercial building systems

    Energy Technology Data Exchange (ETDEWEB)

    Selkowitz, Stephen

    2003-10-01

    This report summarizes key technical accomplishments resulting from the three year PIER-funded R&D program, ''High Performance Commercial Building Systems'' (HPCBS). The program targets the commercial building sector in California, an end-use sector that accounts for about one-third of all California electricity consumption and an even larger fraction of peak demand, at a cost of over $10B/year. Commercial buildings also have a major impact on occupant health, comfort and productivity. Building design and operations practices that influence energy use are deeply engrained in a fragmented, risk-averse industry that is slow to change. Although California's aggressive standards efforts have resulted in new buildings designed to use less energy than those constructed 20 years ago, the actual savings realized are still well below technical and economic potentials. The broad goal of this program is to develop and deploy a set of energy-saving technologies, strategies, and techniques, and improve processes for designing, commissioning, and operating commercial buildings, while improving health, comfort, and performance of occupants, all in a manner consistent with sound economic investment practices. Results are to be broadly applicable to the commercial sector for different building sizes and types, e.g. offices and schools, for different classes of ownership, both public and private, and for owner-occupied as well as speculative buildings. The program aims to facilitate significant electricity use savings in the California commercial sector by 2015, while assuring that these savings are affordable and promote high quality indoor environments. The five linked technical program elements contain 14 projects with 41 distinct R&D tasks. Collectively they form a comprehensive Research, Development, and Demonstration (RD&D) program with the potential to capture large savings in the commercial building sector, providing significant economic benefits to

  19. Simple machines

    CERN Document Server

    Graybill, George

    2007-01-01

    Just how simple are simple machines? With our ready-to-use resource, they are simple to teach and easy to learn! Chocked full of information and activities, we begin with a look at force, motion and work, and examples of simple machines in daily life are given. With this background, we move on to different kinds of simple machines including: Levers, Inclined Planes, Wedges, Screws, Pulleys, and Wheels and Axles. An exploration of some compound machines follows, such as the can opener. Our resource is a real time-saver as all the reading passages, student activities are provided. Presented in s

  20. Convergent Polishing: A Simple, Rapid, Full Aperture Polishing Process of High Quality Optical Flats & Spheres

    Science.gov (United States)

    Suratwala, Tayyab; Steele, Rusty; Feit, Michael; Dylla-Spears, Rebecca; Desjardin, Richard; Mason, Dan; Wong, Lana; Geraghty, Paul; Miller, Phil; Shen, Nan

    2014-01-01

    Convergent Polishing is a novel polishing system and method for finishing flat and spherical glass optics in which a workpiece, independent of its initial shape (i.e., surface figure), will converge to final surface figure with excellent surface quality under a fixed, unchanging set of polishing parameters in a single polishing iteration. In contrast, conventional full aperture polishing methods require multiple, often long, iterative cycles involving polishing, metrology and process changes to achieve the desired surface figure. The Convergent Polishing process is based on the concept of workpiece-lap height mismatch resulting in pressure differential that decreases with removal and results in the workpiece converging to the shape of the lap. The successful implementation of the Convergent Polishing process is a result of the combination of a number of technologies to remove all sources of non-uniform spatial material removal (except for workpiece-lap mismatch) for surface figure convergence and to reduce the number of rogue particles in the system for low scratch densities and low roughness. The Convergent Polishing process has been demonstrated for the fabrication of both flats and spheres of various shapes, sizes, and aspect ratios on various glass materials. The practical impact is that high quality optical components can be fabricated more rapidly, more repeatedly, with less metrology, and with less labor, resulting in lower unit costs. In this study, the Convergent Polishing protocol is specifically described for fabricating 26.5 cm square fused silica flats from a fine ground surface to a polished ~λ/2 surface figure after polishing 4 hr per surface on a 81 cm diameter polisher. PMID:25489745

  1. High-dose biotin therapy leading to false biochemical endocrine profiles: validation of a simple method to overcome biotin interference.

    Science.gov (United States)

    Piketty, Marie-Liesse; Prie, Dominique; Sedel, Frederic; Bernard, Delphine; Hercend, Claude; Chanson, Philippe; Souberbielle, Jean-Claude

    2017-05-01

    High-dose biotin therapy is beneficial in progressive multiple sclerosis (MS) and is expected to be adopted by a large number of patients. Biotin therapy leads to analytical interference in many immunoassays that utilize streptavidin-biotin capture techniques, yielding skewed results that can mimic various endocrine disorders. We aimed at exploring this interference, to be able to remove biotin and avoid misleading results. We measured free triiodothyronine (fT3), free thyroxine (fT4), thyroid-stimulating hormone (TSH), parathyroid homrone (PTH), 25-hydroxyvitamin D (25OHD), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, C-peptide, cortisol (Roche Diagnostics assays), biotin and its main metabolites (liquid chromatography tandem mass spectrometry) in 23 plasmas from MS patients and healthy volunteers receiving high-dose biotin, and in 39 biotin-unsupplemented patients, before and after a simple procedure (designated N5) designed to remove biotin by means of streptavidin-coated microparticles. We also assayed fT4, TSH and PTH in the 23 high-biotin plasmas using assays not employing streptavidin-biotin binding. The biotin concentration ranged from 31.7 to 1160 µg/L in the 23 high-biotin plasmas samples. After the N5 protocol, the biotin concentration was below the detection limit in all but two samples (8.3 and 27.6 μg/L). Most hormones results were abnormal, but normalized after N5. All results with the alternative methods were normal except two slight PTH elevations. In the 39 biotin-unsupplemented patients, the N5 protocol did not affect the results for any of the hormones, apart from an 8.4% decrease in PTH. We confirm that most streptavidin-biotin hormone immunoassays are affected by high biotin concentrations, leading to a risk of misdiagnosis. Our simple neutralization method efficiently suppresses biotin interference.

  2. Hypoxanthine as a predictor of performance in highly trained athletes.

    Science.gov (United States)

    Zieliński, J; Krasińska, B; Kusy, K

    2013-12-01

    Purine metabolism reflects the exercise-induced muscle adaptations and training status. This study evaluated the utility of plasma hypoxanthine in the prediction of actual sport performance. We studied male athletes: 28 triathletes (21.4±2.9 years), 12 long-distance runners (23.2±1.9 years), 13 middle-distance runners (22.9±1.8 years) and 18 sprinters (22.0±2.7 years). Season-best race times were considered, achieved over standard triathlon, 5 000 m, 1 500 m and 100 m, respectively. Incremental treadmill test was administered to determine maximum and "threshold" oxygen uptake. Resting and post-exercise plasma concentrations of hypoxanthine, xanthine, uric acid and lactate were measured as well as resting erythrocyte hypoxanthine-guanine phosphoribosyltransferase activity. Simple and multiple regression analyses were used to identify significant contributors to the variance in performance. Hypoxanthine considered alone explained more variance in triathletes, long-distance runners, middle-distance runners and sprinters (r 2=0.81, 0.81, 0.88 and 0.78, respectively) than models based on aerobic capacity and lactate (R 2=0.51, 0.37, 0.59 and 0.31, respectively). Combining purine metabolites and cardiorespiratory variables resulted in the best prediction (R 2=0.86, 0.93, 0.93 and 0.91; r=0.93, 0.96, 0.96 and 0.95, respectively). In summary, hypoxanthine is a strong predictor of performance in highly trained athletes and its prediction ability is very high regardless of sport specialization, spanning the continuum from speed-power to endurance disciplines. © Georg Thieme Verlag KG Stuttgart · New York.

  3. Improving the high performance concrete (HPC behaviour in high temperatures

    Directory of Open Access Journals (Sweden)

    Cattelan Antocheves De Lima, R.

    2003-12-01

    Full Text Available High performance concrete (HPC is an interesting material that has been long attracting the interest from the scientific and technical community, due to the clear advantages obtained in terms of mechanical strength and durability. Given these better characteristics, HFC, in its various forms, has been gradually replacing normal strength concrete, especially in structures exposed to severe environments. However, the veiy dense microstructure and low permeability typical of HPC can result in explosive spalling under certain thermal and mechanical conditions, such as when concrete is subject to rapid temperature rises, during a f¡re. This behaviour is caused by the build-up of internal water pressure, in the pore structure, during heating, and by stresses originating from thermal deformation gradients. Although there are still a limited number of experimental programs in this area, some researchers have reported that the addition of polypropylene fibers to HPC is a suitable way to avoid explosive spalling under f re conditions. This change in behavior is derived from the fact that polypropylene fibers melt in high temperatures and leave a pathway for heated gas to escape the concrete matrix, therefore allowing the outward migration of water vapor and resulting in the reduction of interned pore pressure. The present research investigates the behavior of high performance concrete on high temperatures, especially when polypropylene fibers are added to the mix.

    El hormigón de alta resistencia (HAR es un material de gran interés para la comunidad científica y técnica, debido a las claras ventajas obtenidas en término de resistencia mecánica y durabilidad. A causa de estas características, el HAR, en sus diversas formas, en algunas aplicaciones está reemplazando gradualmente al hormigón de resistencia normal, especialmente en estructuras expuestas a ambientes severos. Sin embargo, la microestructura muy densa y la baja permeabilidad t

  4. High performance ultrasonic field simulation on complex geometries

    Science.gov (United States)

    Chouh, H.; Rougeron, G.; Chatillon, S.; Iehl, J. C.; Farrugia, J. P.; Ostromoukhov, V.

    2016-02-01

    Ultrasonic field simulation is a key ingredient for the design of new testing methods as well as a crucial step for NDT inspection simulation. As presented in a previous paper [1], CEA-LIST has worked on the acceleration of these simulations focusing on simple geometries (planar interfaces, isotropic materials). In this context, significant accelerations were achieved on multicore processors and GPUs (Graphics Processing Units), bringing the execution time of realistic computations in the 0.1 s range. In this paper, we present recent works that aim at similar performances on a wider range of configurations. We adapted the physical model used by the CIVA platform to design and implement a new algorithm providing a fast ultrasonic field simulation that yields nearly interactive results for complex cases. The improvements over the CIVA pencil-tracing method include adaptive strategies for pencil subdivisions to achieve a good refinement of the sensor geometry while keeping a reasonable number of ray-tracing operations. Also, interpolation of the times of flight was used to avoid time consuming computations in the impulse response reconstruction stage. To achieve the best performance, our algorithm runs on multi-core superscalar CPUs and uses high performance specialized libraries such as Intel Embree for ray-tracing, Intel MKL for signal processing and Intel TBB for parallelization. We validated the simulation results by comparing them to the ones produced by CIVA on identical test configurations including mono-element and multiple-element transducers, homogeneous, meshed 3D CAD specimens, isotropic and anisotropic materials and wave paths that can involve several interactions with interfaces. We show performance results on complete simulations that achieve computation times in the 1s range.

  5. A Simulation Study on the Performance of the Simple Difference and Covariance-Adjusted Scores in Randomized Experimental Designs

    Science.gov (United States)

    Petscher, Yaacov; Schatschneider, Christopher

    2011-01-01

    Research by Huck and McLean (1975) demonstrated that the covariance-adjusted score is more powerful than the simple difference score, yet recent reviews indicate researchers are equally likely to use either score type in two-wave randomized experimental designs. A Monte Carlo simulation was conducted to examine the conditions under which the…

  6. Spectrally high performing quantum cascade lasers

    Science.gov (United States)

    Toor, Fatima

    Quantum cascade (QC) lasers are versatile semiconductor light sources that can be engineered to emit light of almost any wavelength in the mid- to far-infrared (IR) and terahertz region from 3 to 300 mum [1-5]. Furthermore QC laser technology in the mid-IR range has great potential for applications in environmental, medical and industrial trace gas sensing [6-10] since several chemical vapors have strong rovibrational frequencies in this range and are uniquely identifiable by their absorption spectra through optical probing of absorption and transmission. Therefore, having a wide range of mid-IR wavelengths in a single QC laser source would greatly increase the specificity of QC laser-based spectroscopic systems, and also make them more compact and field deployable. This thesis presents work on several different approaches to multi-wavelength QC laser sources that take advantage of band-structure engineering and the uni-polar nature of QC lasers. Also, since for chemical sensing, lasers with narrow linewidth are needed, work is presented on a single mode distributed feedback (DFB) QC laser. First, a compact four-wavelength QC laser source, which is based on a 2-by-2 module design, with two waveguides having QC laser stacks for two different emission wavelengths each, one with 7.0 mum/11.2 mum, and the other with 8.7 mum/12.0 mum is presented. This is the first design of a four-wavelength QC laser source with widely different emission wavelengths that uses minimal optics and electronics. Second, since there are still several unknown factors that affect QC laser performance, results on a first ever study conducted to determine the effects of waveguide side-wall roughness on QC laser performance using the two-wavelength waveguides is presented. The results are consistent with Rayleigh scattering effects in the waveguides, with roughness effecting shorter wavelengths more than longer wavelengths. Third, a versatile time-multiplexed multi-wavelength QC laser system that

  7. Nova performance at ultra high fluence levels

    International Nuclear Information System (INIS)

    Hunt, J.T.

    1986-01-01

    Nova is a ten beam high power Nd:glass laser used for interial confinement fusion research. It was operated in the high power high energy regime following the completion of construction in December 1984. During this period several interesting nonlinear optical phenomena were observed. These phenomena are discussed in the text. 11 refs., 5 figs

  8. WARRIOR II, a high performance modular electric robot system

    International Nuclear Information System (INIS)

    Downton, G.C.

    1996-01-01

    A high performance electric robot, WARRIOR, was built for in-reactor welding at the Oldbury nuclear power plant in the United Kingdom in the mid 1980s. WARRIOR II has been developed as a lighter, smaller diameter articulated welding robot which can be deployed on its umbilical down a stand pipe for remote docking with the manipulator system which delivers it to its work site. A key feature of WARRIOR II has been the development of a prototype spherical modular joint. The module provides the drive torque necessary to motivate the robot arm, acts as the joint bearing, has standard mechanical interfaces for the limb sections, accurately measures the joint angle and has cable services running through the centre. It can act either as a bend or rotate joint and the interconnecting limb sections need only to be simple tubular sections. A wide range of manipulator configurations to suit the access constraints of particular problems can be achieved with a set of joint modules and limb sections. A general purpose motion controller has also been developed which is capable of kinematically controlling any configuration of WARRIOR II thus contributing to the realisation of the concept of a general purpose tool which can be used over and over again, at short notice, in any situation where a high precision, light weight, versatile manipulator is required. (UK)

  9. Durability and Performance of High Performance Infiltration Cathodes

    DEFF Research Database (Denmark)

    Samson, Alfred Junio; Søgaard, Martin; Hjalmarsson, Per

    2013-01-01

    The performance and durability of solid oxide fuel cell (SOFC) cathodes consisting of a porous Ce0.9Gd0.1O1.95 (CGO) infiltrated with nitrates corresponding to the nominal compositions La0.6Sr0.4Co1.05O3-δ (LSC), LaCoO3-δ (LC), and Co3O4 are discussed. At 600°C, the polarization resistance, Rp......, varied as: LSC (0.062Ωcm2)cathode was found to depend on the infiltrate firing temperature and is suggested to originate...... of the infiltrate but also from a better surface exchange property. A 450h test of an LSC-infiltrated CGO cathode showed an Rp with final degradation rate of only 11mΩcm2kh-1. An SOFC with an LSC-infiltrated CGO cathode tested for 1,500h at 700°C and 0.5Acm-2 (60% fuel, 20% air utilization) revealed no measurable...

  10. High Performance Computing in Science and Engineering '02 : Transactions of the High Performance Computing Center

    CERN Document Server

    Jäger, Willi

    2003-01-01

    This book presents the state-of-the-art in modeling and simulation on supercomputers. Leading German research groups present their results achieved on high-end systems of the High Performance Computing Center Stuttgart (HLRS) for the year 2002. Reports cover all fields of supercomputing simulation ranging from computational fluid dynamics to computer science. Special emphasis is given to industrially relevant applications. Moreover, by presenting results for both vector sytems and micro-processor based systems the book allows to compare performance levels and usability of a variety of supercomputer architectures. It therefore becomes an indispensable guidebook to assess the impact of the Japanese Earth Simulator project on supercomputing in the years to come.

  11. From adaptive to high-performance structures

    NARCIS (Netherlands)

    Teuffel, P.

    2011-01-01

    Multiple design aspects influence the building performance such as architectural criteria, various environmental impacts and user behaviour. Specific examples are sun, wind, temperatures, function, occupancy, socio-cultural aspects and other contextual aspects and needs. Even though these aspects

  12. High-performance-vehicle technology. [fighter aircraft propulsion

    Science.gov (United States)

    Povinelli, L. A.

    1979-01-01

    Propulsion needs of high performance military aircraft are discussed. Inlet performance, nozzle performance and cooling, and afterburner performance are covered. It is concluded that nonaxisymmetric nozzles provide cleaner external lines and enhanced maneuverability, but the internal flows are more complex. Swirl afterburners show promise for enhanced performance in the high altitude, low Mach number region.

  13. Simple and cost-effective method of highly conductive and elastic carbon nanotube/polydimethylsiloxane composite for wearable electronics.

    Science.gov (United States)

    Kim, Jeong Hun; Hwang, Ji-Young; Hwang, Ha Ryeon; Kim, Han Seop; Lee, Joong Hoon; Seo, Jae-Won; Shin, Ueon Sang; Lee, Sang-Hoon

    2018-01-22

    The development of various flexible and stretchable materials has attracted interest for promising applications in biomedical engineering and electronics industries. This interest in wearable electronics, stretchable circuits, and flexible displays has created a demand for stable, easily manufactured, and cheap materials. However, the construction of flexible and elastic electronics, on which commercial electronic components can be mounted through simple and cost-effective processing, remains challenging. We have developed a nanocomposite of carbon nanotubes (CNTs) and polydimethylsiloxane (PDMS) elastomer. To achieve uniform distributions of CNTs within the polymer, an optimized dispersion process was developed using isopropyl alcohol (IPA) and methyl-terminated PDMS in combination with ultrasonication. After vaporizing the IPA, various shapes and sizes can be easily created with the nanocomposite, depending on the mold. The material provides high flexibility, elasticity, and electrical conductivity without requiring a sandwich structure. It is also biocompatible and mechanically stable, as demonstrated by cytotoxicity assays and cyclic strain tests (over 10,000 times). We demonstrate the potential for the healthcare field through strain sensor, flexible electric circuits, and biopotential measurements such as EEG, ECG, and EMG. This simple and cost-effective fabrication method for CNT/PDMS composites provides a promising process and material for various applications of wearable electronics.

  14. RISC Processors and High Performance Computing

    Science.gov (United States)

    Bailey, David H.; Saini, Subhash; Craw, James M. (Technical Monitor)

    1995-01-01

    This tutorial will discuss the top five RISC microprocessors and the parallel systems in which they are used. It will provide a unique cross-machine comparison not available elsewhere. The effective performance of these processors will be compared by citing standard benchmarks in the context of real applications. The latest NAS Parallel Benchmarks, both absolute performance and performance per dollar, will be listed. The next generation of the NPB will be described. The tutorial will conclude with a discussion of future directions in the field. Technology Transfer Considerations: All of these computer systems are commercially available internationally. Information about these processors is available in the public domain, mostly from the vendors themselves. The NAS Parallel Benchmarks and their results have been previously approved numerous times for public release, beginning back in 1991.

  15. Psychological factors in developing high performance athletes

    DEFF Research Database (Denmark)

    Elbe, Anne-Marie; Wikman, Johan Michael

    2017-01-01

    calls for great efforts in dealing with competitive pressure and demands mental strength with regard to endurance, self-motivation and willpower. But while it is somewhat straightforward to specify the physical and physiological skills needed for top performance in a specific sport, it becomes less...... clear with regard to the psychological skills that are needed. Therefore, the main questions to be addressed in this chapter are: (1) which psychological skills are needed to reach top performance? And (2) (how) can these skills be developed in young talents?...

  16. High Performance Expectations: Concept and causes

    DEFF Research Database (Denmark)

    Andersen, Lotte Bøgh; Jacobsen, Christian Bøtcher

    2017-01-01

    literature research, HPE is defined as the degree to which leaders succeed in expressing ambitious expectations to their employees’ achievement of given performance criteria, and it is analyzed how leadership behavior affects employee-perceived HPE. This study applies a large-scale leadership field...... experiment with 3,730 employees nested in 471 organizations and finds that transformational leadership training as well as transactional and combined training of the leaders significantly increased employees’ HPE relative to a control group. Furthermore, transformational leadership and the use of pecuniary...... rewards seem to be important mechanisms. This implies that public leaders can actually affect HPE through their leadership and thus potentially organizational performance as well....

  17. High-performance, scalable optical network-on-chip architectures

    Science.gov (United States)

    Tan, Xianfang

    The rapid advance of technology enables a large number of processing cores to be integrated into a single chip which is called a Chip Multiprocessor (CMP) or a Multiprocessor System-on-Chip (MPSoC) design. The on-chip interconnection network, which is the communication infrastructure for these processing cores, plays a central role in a many-core system. With the continuously increasing complexity of many-core systems, traditional metallic wired electronic networks-on-chip (NoC) became a bottleneck because of the unbearable latency in data transmission and extremely high energy consumption on chip. Optical networks-on-chip (ONoC) has been proposed as a promising alternative paradigm for electronic NoC with the benefits of optical signaling communication such as extremely high bandwidth, negligible latency, and low power consumption. This dissertation focus on the design of high-performance and scalable ONoC architectures and the contributions are highlighted as follow: 1. A micro-ring resonator (MRR)-based Generic Wavelength-routed Optical Router (GWOR) is proposed. A method for developing any sized GWOR is introduced. GWOR is a scalable non-blocking ONoC architecture with simple structure, low cost and high power efficiency compared to existing ONoC designs. 2. To expand the bandwidth and improve the fault tolerance of the GWOR, a redundant GWOR architecture is designed by cascading different type of GWORs into one network. 3. The redundant GWOR built with MRR-based comb switches is proposed. Comb switches can expand the bandwidth while keep the topology of GWOR unchanged by replacing the general MRRs with comb switches. 4. A butterfly fat tree (BFT)-based hybrid optoelectronic NoC (HONoC) architecture is developed in which GWORs are used for global communication and electronic routers are used for local communication. The proposed HONoC uses less numbers of electronic routers and links than its counterpart of electronic BFT-based NoC. It takes the advantages of

  18. High Rate Performing Li-ion Battery

    Science.gov (United States)

    2015-02-09

    journal article will be sufficient in most cases. This document may be as long or as short as needed to give a fair account of the work performed...Klink, J. J. & Moser, J. EPR Study of Vanadium (4+) in the Anatase and Rutile Phases of TiO2. Phys. Rev. B 34, 3060-3068 (1986). 40 Abragam, A

  19. Engendering a high performing organisational culture through ...

    African Journals Online (AJOL)

    Concluding that Africa's poor organisational performances are attributable to some inadequacies in the cultural foundations of countries and organisations, this paper argues for internal branding as the way forward for African organisations. Through internal branding an African organization can use a systematic and ...

  20. Mastering JavaScript high performance

    CERN Document Server

    Adams, Chad R

    2015-01-01

    If you are a JavaScript developer with some experience in development and want to increase the performance of JavaScript projects by building faster web apps, then this book is for you. You should know the basic concepts of JavaScript.

  1. Gamma and Xray spectroscopy at high performance

    International Nuclear Information System (INIS)

    Borchert, G.L.

    1984-01-01

    The author determines that for many interesting problems in gamma and Xray spectroscopy it is necessary to use crystal diffractometers. The basic features of such instruments are discussed and the special performance of crystal spectrometers is demonstrated by means of typical examples of various applications

  2. High Performance Fortran for Aerospace Applications

    National Research Council Canada - National Science Library

    Mehrotra, Piyush

    2000-01-01

    .... HPF is a set of Fortran extensions designed to provide users with a high-level interface for programming data parallel scientific applications while delegating to the compiler/runtime system the task...

  3. High-Performance Computing Paradigm and Infrastructure

    CERN Document Server

    Yang, Laurence T

    2006-01-01

    With hyperthreading in Intel processors, hypertransport links in next generation AMD processors, multi-core silicon in today's high-end microprocessors from IBM and emerging grid computing, parallel and distributed computers have moved into the mainstream

  4. High performance management bij franchise-supermarkten

    NARCIS (Netherlands)

    Sloot, Laurens; van Nierop, Erjen; de Waal, Andre

    In dit artikel wordt een onderzoek gepresenteerd naar de mate waarin franchise-supermarkten voldoen aan de vijf factoren van high performanceorganisaties (HPO): hoge kwaliteit managers, hoge kwaliteit medewerkers, openheid en actiegerichtheid, continue verbetering en vernieuwing, en

  5. High performance fuel technology development : Development of high performance cladding materials

    International Nuclear Information System (INIS)

    Park, Jeongyong; Jeong, Y. H.; Park, S. Y.

    2012-04-01

    The superior in-pile performance of the HANA claddings have been verified by the successful irradiation test and in the Halden research reactor up to the high burn-up of 67GWD/MTU. The in-pile corrosion and creep resistances of HANA claddings were improved by 40% and 50%, respectively, over Zircaloy-4. HANA claddings have been also irradiated in the commercial reactor up to 2 reactor cycles, showing the corrosion resistance 40% better than that of ZIRLO in the same fuel assembly. Long-term out-of-pile performance tests for the candidates of the next generation cladding materials have produced the highly reliable test results. The final candidate alloys were selected and they showed the corrosion resistance 50% better than the foreign advanced claddings, which is beyond the original target. The LOCA-related properties were also improved by 20% over the foreign advanced claddings. In order to establish the optimal manufacturing process for the inner and outer claddings of the dual-cooled fuel, 18 different kinds of specimens were fabricated with various cold working and annealing conditions. Based on the performance tests and various out-of-pile test results obtained from the specimens, the optimal manufacturing process was established for the inner and outer cladding tubes of the dual-cooled fuel

  6. A simple magnetic balance technique for determining transition temperatures of high T/sub c/ superconducting powders

    International Nuclear Information System (INIS)

    Takamori, T.; Dove, D.B.

    1988-01-01

    A simple arrangement is described that provides a convenient method for determining transition behavior of high Tc superconductors that are in powder form. A single-pan balance was modified so that its deviation from balance could be measured by an inductive displacement transducer. A small magnet was attached to the balance and placed in close proximity above the sample to be measured. As the sample is cooled through the transition, magnetic flux lines are locally excluded resulting in a repulsive force on the magnet attached to the balance. The resulting deflection of the balance has sufficient sensitivity to allow measurements on several mg of powder. This technique provides a convenient method for routine surveying of powder samples during materials development. Example measurements are described

  7. The simple fool's guide to population genomics via RNA-Seq: An introduction to high-throughput sequencing data analysis

    DEFF Research Database (Denmark)

    De Wit, P.; Pespeni, M.H.; Ladner, J.T.

    2012-01-01

    to Population Genomics via RNA-seq' (SFG), a document intended to serve as an easy-to-follow protocol, walking a user through one example of high-throughput sequencing data analysis of nonmodel organisms. It is by no means an exhaustive protocol, but rather serves as an introduction to the bioinformatic methods...... used in population genomics, enabling a user to gain familiarity with basic analysis steps. The SFG consists of two parts. This document summarizes the steps needed and lays out the basic themes for each and a simple approach to follow. The second document is the full SFG, publicly available at http://sfg.......stanford.edu, that includes detailed protocols for data processing and analysis, along with a repository of custom-made scripts and sample files. Steps included in the SFG range from tissue collection to de novo assembly, blast annotation, alignment, gene expression, functional enrichment, SNP detection, principal components...

  8. CO2-Philic polymer membrane with extremely high separation performance

    KAUST Repository

    Yave, Wilfredo

    2010-01-12

    Polymeric membranes are attractive for CO2 separation and concentration from different gas streams because of their versatility and energy efficiency; they can compete with, and they may even replace, traditional absorption processes. Here we describe a simple and powerful method for developing nanostructured and CO2-philic polymer membranes for CO2 separation. A poly(ethylene oxide)-poly(butylene terephthalate) multiblock copolymer is used as membrane material. Smart additives such as polyethylene glycol dibutyl ether are incorporated as spacers or fillers for producing nanostructured materials. The addition of these specific additives produces CO2-philic membranes and increases the CO2 permeability (750 barrer) up to five-fold without the loss of selectivity. The membranes present outstanding performance for CO2 separation, and the measured CO2 flux is extremely high ( > 2 m3 m -2 h-1 bar-1) with selectivity over H2 and N2 of 10 and 40, respectively, making them attractive for CO 2 capture. © 2009 American Chemical Society.

  9. CO2-Philic polymer membrane with extremely high separation performance

    KAUST Repository

    Yave, Wilfredo; Car, Anja; Funari, S.; Nunes, Suzana Pereira; Peinemann, Klaus-Viktor

    2010-01-01

    Polymeric membranes are attractive for CO2 separation and concentration from different gas streams because of their versatility and energy efficiency; they can compete with, and they may even replace, traditional absorption processes. Here we describe a simple and powerful method for developing nanostructured and CO2-philic polymer membranes for CO2 separation. A poly(ethylene oxide)-poly(butylene terephthalate) multiblock copolymer is used as membrane material. Smart additives such as polyethylene glycol dibutyl ether are incorporated as spacers or fillers for producing nanostructured materials. The addition of these specific additives produces CO2-philic membranes and increases the CO2 permeability (750 barrer) up to five-fold without the loss of selectivity. The membranes present outstanding performance for CO2 separation, and the measured CO2 flux is extremely high ( > 2 m3 m -2 h-1 bar-1) with selectivity over H2 and N2 of 10 and 40, respectively, making them attractive for CO 2 capture. © 2009 American Chemical Society.

  10. Menhir: An Environment for High Performance Matlab

    Directory of Open Access Journals (Sweden)

    Stéphane Chauveau

    1999-01-01

    Full Text Available In this paper we present Menhir a compiler for generating sequential or parallel code from the Matlab language. The compiler has been designed in the context of using Matlab as a specification language. One of the major features of Menhir is its retargetability to generate parallel and sequential C or Fortran code. We present the compilation process and the target system description for Menhir. Preliminary performances are given and compared with MCC, the MathWorks Matlab compiler.

  11. Inclusion control in high-performance steels

    International Nuclear Information System (INIS)

    Holappa, L.E.K.; Helle, A.S.

    1995-01-01

    Progress of clean steel production, fundamentals of oxide and sulphide inclusions as well as inclusion morphology in normal and calcium treated steels are described. Effects of cleanliness and inclusion control on steel properties are discussed. In many damaging constructional and engineering applications the nonmetallic inclusions have a quite decisive role in steel performance. An example of combination of good mechanical properties and superior machinability by applying inclusion control is presented. (author)

  12. Emerging technologies for high performance infrared detectors

    OpenAIRE

    Tan Chee Leong; Mohseni Hooman

    2018-01-01

    Infrared photodetectors (IRPDs) have become important devices in various applications such as night vision, military missile tracking, medical imaging, industry defect imaging, environmental sensing, and exoplanet exploration. Mature semiconductor technologies such as mercury cadmium telluride and III–V material-based photodetectors have been dominating the industry. However, in the last few decades, significant funding and research has been focused to improve the performance of IRPDs such as...

  13. A simple method to retrospectively estimate patient dose-area product for chest tomosynthesis examinations performed using VolumeRAD.

    Science.gov (United States)

    Båth, Magnus; Söderman, Christina; Svalkvist, Angelica

    2014-10-01

    The purpose of the present work was to develop and validate a method of retrospectively estimating the dose-area product (DAP) of a chest tomosynthesis examination performed using the VolumeRAD system (GE Healthcare, Chalfont St. Giles, UK) from digital imaging and communications in medicine (DICOM) data available in the scout image. DICOM data were retrieved for 20 patients undergoing chest tomosynthesis using VolumeRAD. Using information about how the exposure parameters for the tomosynthesis examination are determined by the scout image, a correction factor for the adjustment in field size with projection angle was determined. The correction factor was used to estimate the DAP for 20 additional chest tomosynthesis examinations from DICOM data available in the scout images, which was compared with the actual DAP registered for the projection radiographs acquired during the tomosynthesis examination. A field size correction factor of 0.935 was determined. Applying the developed method using this factor, the average difference between the estimated DAP and the actual DAP was 0.2%, with a standard deviation of 0.8%. However, the difference was not normally distributed and the maximum error was only 1.0%. The validity and reliability of the presented method were thus very high. A method to estimate the DAP of a chest tomosynthesis examination performed using the VolumeRAD system from DICOM data in the scout image was developed and validated. As the scout image normally is the only image connected to the tomosynthesis examination stored in the picture archiving and communication system (PACS) containing dose data, the method may be of value for retrospectively estimating patient dose in clinical use of chest tomosynthesis.

  14. A simple method to retrospectively estimate patient dose-area product for chest tomosynthesis examinations performed using VolumeRAD

    Energy Technology Data Exchange (ETDEWEB)

    Båth, Magnus, E-mail: magnus.bath@vgregion.se; Svalkvist, Angelica [Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy at University of Gothenburg, Gothenburg SE-413 45, Sweden and Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg SE-413 45 (Sweden); Söderman, Christina [Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy at University of Gothenburg, Gothenburg SE-413 45 (Sweden)

    2014-10-15

    Purpose: The purpose of the present work was to develop and validate a method of retrospectively estimating the dose-area product (DAP) of a chest tomosynthesis examination performed using the VolumeRAD system (GE Healthcare, Chalfont St. Giles, UK) from digital imaging and communications in medicine (DICOM) data available in the scout image. Methods: DICOM data were retrieved for 20 patients undergoing chest tomosynthesis using VolumeRAD. Using information about how the exposure parameters for the tomosynthesis examination are determined by the scout image, a correction factor for the adjustment in field size with projection angle was determined. The correction factor was used to estimate the DAP for 20 additional chest tomosynthesis examinations from DICOM data available in the scout images, which was compared with the actual DAP registered for the projection radiographs acquired during the tomosynthesis examination. Results: A field size correction factor of 0.935 was determined. Applying the developed method using this factor, the average difference between the estimated DAP and the actual DAP was 0.2%, with a standard deviation of 0.8%. However, the difference was not normally distributed and the maximum error was only 1.0%. The validity and reliability of the presented method were thus very high. Conclusions: A method to estimate the DAP of a chest tomosynthesis examination performed using the VolumeRAD system from DICOM data in the scout image was developed and validated. As the scout image normally is the only image connected to the tomosynthesis examination stored in the picture archiving and communication system (PACS) containing dose data, the method may be of value for retrospectively estimating patient dose in clinical use of chest tomosynthesis.

  15. A simple method to retrospectively estimate patient dose-area product for chest tomosynthesis examinations performed using VolumeRAD

    International Nuclear Information System (INIS)

    Båth, Magnus; Svalkvist, Angelica; Söderman, Christina

    2014-01-01

    Purpose: The purpose of the present work was to develop and validate a method of retrospectively estimating the dose-area product (DAP) of a chest tomosynthesis examination performed using the VolumeRAD system (GE Healthcare, Chalfont St. Giles, UK) from digital imaging and communications in medicine (DICOM) data available in the scout image. Methods: DICOM data were retrieved for 20 patients undergoing chest tomosynthesis using VolumeRAD. Using information about how the exposure parameters for the tomosynthesis examination are determined by the scout image, a correction factor for the adjustment in field size with projection angle was determined. The correction factor was used to estimate the DAP for 20 additional chest tomosynthesis examinations from DICOM data available in the scout images, which was compared with the actual DAP registered for the projection radiographs acquired during the tomosynthesis examination. Results: A field size correction factor of 0.935 was determined. Applying the developed method using this factor, the average difference between the estimated DAP and the actual DAP was 0.2%, with a standard deviation of 0.8%. However, the difference was not normally distributed and the maximum error was only 1.0%. The validity and reliability of the presented method were thus very high. Conclusions: A method to estimate the DAP of a chest tomosynthesis examination performed using the VolumeRAD system from DICOM data in the scout image was developed and validated. As the scout image normally is the only image connected to the tomosynthesis examination stored in the picture archiving and communication system (PACS) containing dose data, the method may be of value for retrospectively estimating patient dose in clinical use of chest tomosynthesis

  16. High-Temperature-Short-Time Annealing Process for High-Performance Large-Area Perovskite Solar Cells.

    Science.gov (United States)

    Kim, Minjin; Kim, Gi-Hwan; Oh, Kyoung Suk; Jo, Yimhyun; Yoon, Hyun; Kim, Ka-Hyun; Lee, Heon; Kim, Jin Young; Kim, Dong Suk

    2017-06-27

    Organic-inorganic hybrid metal halide perovskite solar cells (PSCs) are attracting tremendous research interest due to their high solar-to-electric power conversion efficiency with a high possibility of cost-effective fabrication and certified power conversion efficiency now exceeding 22%. Although many effective methods for their application have been developed over the past decade, their practical transition to large-size devices has been restricted by difficulties in achieving high performance. Here we report on the development of a simple and cost-effective production method with high-temperature and short-time annealing processing to obtain uniform, smooth, and large-size grain domains of perovskite films over large areas. With high-temperature short-time annealing at 400 °C for 4 s, the perovskite film with an average domain size of 1 μm was obtained, which resulted in fast solvent evaporation. Solar cells fabricated using this processing technique had a maximum power conversion efficiency exceeding 20% over a 0.1 cm 2 active area and 18% over a 1 cm 2 active area. We believe our approach will enable the realization of highly efficient large-area PCSs for practical development with a very simple and short-time procedure. This simple method should lead the field toward the fabrication of uniform large-scale perovskite films, which are necessary for the production of high-efficiency solar cells that may also be applicable to several other material systems for more widespread practical deployment.

  17. Development of a high performance liquid chromatography method ...

    African Journals Online (AJOL)

    Development of a high performance liquid chromatography method for simultaneous ... Purpose: To develop and validate a new low-cost high performance liquid chromatography (HPLC) method for ..... Several papers have reported the use of ...

  18. High Performance Home Building Guide for Habitat for Humanity Affiliates

    Energy Technology Data Exchange (ETDEWEB)

    Lindsey Marburger

    2010-10-01

    This guide covers basic principles of high performance Habitat construction, steps to achieving high performance Habitat construction, resources to help improve building practices, materials, etc., and affiliate profiles and recommendations.

  19. High Performance Computing in Science and Engineering '99 : Transactions of the High Performance Computing Center

    CERN Document Server

    Jäger, Willi

    2000-01-01

    The book contains reports about the most significant projects from science and engineering of the Federal High Performance Computing Center Stuttgart (HLRS). They were carefully selected in a peer-review process and are showcases of an innovative combination of state-of-the-art modeling, novel algorithms and the use of leading-edge parallel computer technology. The projects of HLRS are using supercomputer systems operated jointly by university and industry and therefore a special emphasis has been put on the industrial relevance of results and methods.

  20. High Performance Computing in Science and Engineering '98 : Transactions of the High Performance Computing Center

    CERN Document Server

    Jäger, Willi

    1999-01-01

    The book contains reports about the most significant projects from science and industry that are using the supercomputers of the Federal High Performance Computing Center Stuttgart (HLRS). These projects are from different scientific disciplines, with a focus on engineering, physics and chemistry. They were carefully selected in a peer-review process and are showcases for an innovative combination of state-of-the-art physical modeling, novel algorithms and the use of leading-edge parallel computer technology. As HLRS is in close cooperation with industrial companies, special emphasis has been put on the industrial relevance of results and methods.