WorldWideScience

Sample records for sid effects author

  1. Sudden Infant Death Syndrome (SIDS)

    Science.gov (United States)

    Sudden infant death syndrome (SIDS) Overview Sudden infant death syndrome (SIDS) is the unexplained death, usually during sleep, of a seemingly healthy baby ... year old. SIDS is sometimes known as crib death because the infants often die in their cribs. ...

  2. Is it Time for a Sudden Infant Death Syndrome (SIDS) Awareness Campaign? Community Stakeholders' Perceptions of SIDS.

    Science.gov (United States)

    Gollenberg, Audra; Fendley, Kim

    2018-01-01

    Sudden infant death syndrome (SIDS) remains a leading cause of infant death in the United States and in Virginia, the SIDS rate is higher than the national average. We sought to gauge the perceptions among community-identified stakeholders as to community resource needs to reduce SIDS. We used snowball sampling to identify important community stakeholders to be interviewed as key informants. A semi-structured interview lasting 45 min-2 hours was delivered to determine resource needs to reduce SIDS, and whether high-risk community members were aware of SIDS risk factors among stakeholders representing a variety of disciplines. Interviews were conducted in two geographic areas with higher than average rates of infant mortality, an urban district, Winchester City, VA and a rural district, Page County, VA. A total of 74 interviews were completed with stakeholders in healthcare, health departments, social services, law enforcement, education/childcare, faith-based institutions, non-profit agencies and non-affiliated community members. The majority of respondents perceive that high-risk community members are not aware of factors that can lead to SIDS (50%). Participants suggested that more "education" is needed to further reduce the rates of SIDS in their communities (73%). Respondents detailed that more pervasive, strategic, and multi-channeled education is necessary to reduce cases of SIDS. Community leaders perceive that high-risk community members are not fully aware of risk factors that can lead to SIDS. Maternal/child health stakeholders in these Virginia locales suggested more community-based education as a potential solution to SIDS.

  3. WorldSID Prototype Dummy Biomechanical Responses.

    Science.gov (United States)

    Cesari, D; Compigne, S; Scherer, R; Xu, L; Takahashi, N; Page, M; Asakawa, K; Kostyniuk, G; Hautmann, E; Bortenschlager, K; Sakurai, M; Harigae, T

    2001-11-01

    The results of biomechanical testing of the WorldSID prototype dummy are presented in this paper. The WorldSID dummy is a new, advanced Worldwide Side Impact Dummy that has the anthropometry of a mid-sized adult male. The first prototype of this dummy has been evaluated by the WorldSID Task Group against previously established corridors for its critical body regions. The response corridors are defined in the International Organization of Standardization (ISO) Technical Report 9790. The prototype is the first version of the WorldSID dummy to be built and tested. This dummy has been subjected to a rigorous program of testing to evaluate, first and foremost its biofidelity, but also its repeatability. Following this initial evaluation, any required modifications will be incorporated into a pre-production version of the WorldSID dummy so that it rates "good" to "excellent" on the ISO dummy biofidelity scale - a rating exceeding that of all current side impact dummies. Also, the overall WorldSID repeatability must not exceed a coefficient of variation of 7% at injury assessment level and this has to be verified for the different body regions. The dummy's head, neck, thorax, abdomen and pelvis were evaluated against the ISO technical report requirements. Testing included drop tests, pendulum impacts, and sled tests. The biofidelity rating of the WorldSID prototype was calculated using the weighted biomechanical test response procedure developed by ISO. The paper presents the results of the testing, which give a very positive indication of the dummy's potential. Based on this evaluation of the dummy biofidelity, the WorldSID prototype dummy exhibits a biofidelity rating of 6.15 that corresponds to an ISO biofidelity classification of "fair". In addition, the dummy shows good repeatability with a global coefficient of variation of 3.30% for the pendulum and rigid sled tests.

  4. SiD Letter of Intent

    Energy Technology Data Exchange (ETDEWEB)

    Aihara, H., (Ed.); Burrows, P., (Ed.); Oreglia, M., (Ed.); Berger, E.L.; Guarino, V.; Repond, J.; Weerts, H.; Xia, L.; Zhang, J.; /Argonne, HEP; Zhang, Q.; /Argonne, HEP /Beijing, Inst. High Energy Phys.; Srivastava, A.; /Birla Inst. Tech. Sci.; Butler, J.M.; /Boston U.; Goldstein, Joel; Velthuis, J.; /Bristol U.; Radeka, V.; /Brookhaven; Zhu, R.-Y.; /Caltech.; Lutz, P.; /DAPNIA, Saclay; de Roeck, A.; Elsener, K.; Gaddi, A.; Gerwig, H.; /CERN /Cornell U., LNS /Ewha Women' s U., Seoul /Fermilab /Gent U. /Darmstadt, GSI /Imperial Coll., London /Barcelona, Inst. Microelectron. /KLTE-ATOMKI /Valencia U., IFIC /Cantabria Inst. of Phys. /Louis Pasteur U., Strasbourg I /Durham U., IPPP /Kansas State U. /Kyungpook Natl. U. /Annecy, LAPP /LLNL, Livermore /Louisiana Tech. U. /Paris U., VI-VII /Paris U., VI-VII /Munich, Max Planck Inst. /MIT, LNS /Chicago, CBC /Moscow State U. /Nanjing U. /Northern Illinois U. /Obninsk State Nucl. Eng. U. /Paris U., VI-VII /Strasbourg, IPHC /Prague, Inst. Phys. /Princeton U. /Purdue U. /Rutherford /SLAC /SUNY, Stony Brook /Barcelona U. /Bonn U. /UC, Davis /UC, Santa Cruz /Chicago U. /Colorado U. /Delhi U. /Hawaii U. /Helsinki U. /Indiana U. /Iowa U. /Massachusetts U., Amherst /Melbourne U. /Michigan U. /Minnesota U. /Mississippi U. /Montenegro U. /New Mexico U. /Notre Dame U. /Oregon U. /Oxford U. /Ramon Llull U., Barcelona /Rochester U. /Santiago de Compostela U., IGFAE /Hefei, CUST /Texas U., Arlington /Texas U., Dallas /Tokyo U. /Washington U., Seattle /Wisconsin U., Madison /Wayne State U. /Yale U. /Yonsei U.

    2012-04-11

    This document presents the current status of the Silicon Detector (SiD) effort to develop an optimized design for an experiment at the International Linear Collider. It presents detailed discussions of each of SiD's various subsystems, an overview of the full GEANT4 description of SiD, the status of newly developed tracking and calorimeter reconstruction algorithms, studies of subsystem performance based on these tools, results of physics benchmarking analyses, an estimate of the cost of the detector, and an assessment of the detector R and D needed to provide the technical basis for an optimised SiD.

  5. The current epidemiology of SIDS in Ireland.

    LENUS (Irish Health Repository)

    Mehanni, M

    2000-12-01

    This paper examines some epidemiological factors associated with SIDS to give a general profile of SIDS cases occurring in Ireland between the years 1993 to 1997. There has been a dramatic decrease in the incidence of the Sudden Infant Death Syndrome (SIDS) in the Republic of Ireland in the last decade from an average rate of 2.2\\/1000 live-births in the 1980s to 0.8\\/1000 live-births in the years 1993-1997, a decrease of 100 deaths a year. The fall in the SIDS rate has been seen in many countries and is felt to be associated with Reduce The Risks (RTR) of SIDS campaigns and the avoidance of the prone sleeping position. The use of the prone sleep position averaged at 6% of children being put prone in the years 1993-1997 but the prone position has progressively decreased from 13% of children being put prone in 1994 to only 2% in 1997. The profile of the Irish SIDS cases is similar to that of SIDS cases in other countries following similar RTR campaigns with a male predominance, the characteristic clustering of deaths in the first six months of life and the majority of cases (75%) occuring in the night sleep period. The loss of the seasonal variation of the time of death is also shown and factors such as lower socio-economic status, unemployment and medical card eligibility were seen in higher proportions in SIDS families than in the general population. A high percentage of SIDS mothers smoked (73%). Higher smoking rates were seen among younger and single mothers and smoking rates were inversely related to educational level and socioeconomic grouping. An urgent question that needs to be addressed is how socioeconomic disadvantage increases the SIDS risk and what factors influence socioeconomically disadvantaged families to adopt life style and parenting practices such as smoking that influence their children\\'s health.

  6. The current epidemiology of SIDS in Ireland.

    Science.gov (United States)

    Mehanni, M; Cullen, A; Kiberd, B; McDonnell, M; O'Regan, M; Matthews, T

    2000-12-01

    This paper examines some epidemiological factors associated with SIDS to give a general profile of SIDS cases occurring in Ireland between the years 1993 to 1997. There has been a dramatic decrease in the incidence of the Sudden Infant Death Syndrome (SIDS) in the Republic of Ireland in the last decade from an average rate of 2.2/1000 live-births in the 1980s to 0.8/1000 live-births in the years 1993-1997, a decrease of 100 deaths a year. The fall in the SIDS rate has been seen in many countries and is felt to be associated with Reduce The Risks (RTR) of SIDS campaigns and the avoidance of the prone sleeping position. The use of the prone sleep position averaged at 6% of children being put prone in the years 1993-1997 but the prone position has progressively decreased from 13% of children being put prone in 1994 to only 2% in 1997. The profile of the Irish SIDS cases is similar to that of SIDS cases in other countries following similar RTR campaigns with a male predominance, the characteristic clustering of deaths in the first six months of life and the majority of cases (75%) occuring in the night sleep period. The loss of the seasonal variation of the time of death is also shown and factors such as lower socio-economic status, unemployment and medical card eligibility were seen in higher proportions in SIDS families than in the general population. A high percentage of SIDS mothers smoked (73%). Higher smoking rates were seen among younger and single mothers and smoking rates were inversely related to educational level and socioeconomic grouping. An urgent question that needs to be addressed is how socioeconomic disadvantage increases the SIDS risk and what factors influence socioeconomically disadvantaged families to adopt life style and parenting practices such as smoking that influence their children's health.

  7. Sudden infant death syndrome (SIDS, substance misuse, and smoking in pregnancy

    Directory of Open Access Journals (Sweden)

    Ali K

    2012-10-01

    Full Text Available Kamal Ali, Na’eem Ahmed, Anne GreenoughDivision of Asthma, Allergy, and Lung Biology, Medical Research Council and Asthma UK Center in Allergic Mechanisms of Asthma, King’s College Hospital, London, United KingdomAbstract: In the developed world, sudden infant death syndrome (SIDS remains the leading cause of death in the post neonatal period. This review highlights the association between maternal substance misuse and SIDS, and discusses whether the increased risk is explained by abnormalities of respiratory control. Substance misuse during pregnancy is common, and although the incidence of smoking has declined in recent years among pregnant women, an increasing proportion of mothers of infants who have died of SIDS smoke. The risk of SIDS is increased in women who take opiates, but not cocaine or marijuana, although infants exposed to either of these drugs suffer morbidity, including reduced birth weight. Nicotine exposure increases the risk of SIDS, particularly if both parents smoke, and there is a dose-dependent effect. A variety of respiratory abnormalities have been described in the infants of substance abuse mothers, which may increase their risk of SIDS. These abnormalities include a reduced ability to recover from prolonged apnea and a blunted response to hypoxia and hypercarbia. These results are consistent with postmortem brainstem abnormalities reported among SIDS victims.Keywords: sudden infant death syndrome, nicotine, opiates

  8. 2007 MrSID Image of St. John Utilized to derive Benthic Habitat Maps (18064_c6_ne.sid)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This MrSID (.sid) file is an orthophoto mosaic from a collection of GeoTIFF format natural color and false color infrared orthophotos covering the islands of Puerto...

  9. 2007 MrSID Image of St. John Utilized to derive Benthic Habitat Maps (18064_c7_se.sid)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This MrSID (.sid) file is an orthophoto mosaic from a collection of GeoTIFF format natural color and false color infrared orthophotos covering the islands of Puerto...

  10. 2007 MrSID Image of St. John Utilized to derive Benthic Habitat Maps (18064_c7_nw.sid)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This MrSID (.sid) file is an orthophoto mosaic from a collection of GeoTIFF format natural color and false color infrared orthophotos covering the islands of Puerto...

  11. 2007 MrSID Image of St. John Utilized to derive Benthic Habitat Maps (18064_c6_sw.sid)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This MrSID (.sid) file is an orthophoto mosaic from a collection of GeoTIFF format natural color and false color infrared orthophotos covering the islands of Puerto...

  12. 2007 MrSID Image of St. John Utilized to derive Benthic Habitat Maps (18064_c7_ne.sid)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This MrSID (.sid) file is an orthophoto mosaic from a collection of GeoTIFF format natural color and false color infrared orthophotos covering the islands of Puerto...

  13. Characterisation of Classical Sudden Infant Death Syndrome SIDS and Gray Zone SIDS in Japan Using Japanese Pathology and Autopsy Report 1982-1986 From the Japanese Society of Pathology

    Directory of Open Access Journals (Sweden)

    Toshiko Sawaguchia

    1996-07-01

    Full Text Available There is no standardised criterion on the handling of Classical Sudden Infant Death Syndrome (SIDS and Gray Zone SIDS. Particularly international discussion is needed on the handling of Gray Zone cases. Autopsy findings for Classical SIDS and Gray Zone SIDS in Japan has been analysed in preparing the basic data for this discussion in this report. The material analysed was found in the Japanese Pathology and Autopsy Report from the Japanese Society of Pathology (January 1982 to December 1986. A x2 test was required to find the difference between Classical SIDS and Gray Zone SIDS in each autopsy finding. In addition, factor analysis (the principal factor method with Varimax rotation was carried out to identify the structure of the autopsy findings not only for Gray Zone SIDS but also for Classical SIDS. Using the x2 test a lymph tissue enlargement was found to have a high statistical value in Classical SIDS. Congestion, thymus enlargement, pulmonary oedema, adrenal gland atrophy, lymph tissue enlargement and neonate were recorded with .high factor loadings in Classical SIDS by factor analysis. Pneumonia, premature baby, and cardiomegaly was recorded with high statistical value in Gray Zone SIDS by the x2 test. Asphyxia, congestion, atelectasis, pulmonary emphysema, adrenal gland atrophy, premature baby, thymus hypoplasia, cardial malformation and ectopic hemopoesis were recorded as having high factor loadings in Gray Zone SIDS using factor analysis. Thymus enlargement and adrenal gland atrophy were recorded in the third factor of Gray Zone SIDS having rather high negative factor loading using factor analysis. It is remarkable that asphyxia was extracted in the first factor of Gray Zone SIDS with the highest loading factor using factor analysis. This fact might suggest indirectly that a percentage of Gray Zone SIDS would be underdiagnosed because of a substitutional diagnosis of asphyxia as being an external cause of death in Japan, even in general

  14. What Causes SIDS?

    Science.gov (United States)

    ... Environment Look Like? How Can Caregivers Create a Safe Sleep Environment? Babies Need Tummy ... exactly what causes SIDS at this time. Scientists and health care providers are working very hard to find the cause or causes ...

  15. Is It Time for a Sudden Infant Death Syndrome (SIDS) Awareness Campaign? Community Stakeholders' Perceptions of SIDS

    Science.gov (United States)

    Gollenberg, Audra; Fendley, Kim

    2018-01-01

    Sudden infant death syndrome (SIDS) remains a leading cause of infant death in the United States, and in Virginia. We sought to gauge the perceptions among community-identified stakeholders regarding community resource needs to reduce SIDS. Snowball sampling identified important community stakeholders to be interviewed as key informants. A…

  16. Assessing the determinants of SIDS' pattern toward sustainability: A statistical analysis

    International Nuclear Information System (INIS)

    Romano, Antonio A.; Scandurra, Giuseppe; Carfora, Alfonso; Pansini, Rosaria V.

    2016-01-01

    The aim of this paper is twofold. First, we assess the SIDS' pattern towards energy sustainability. Second, we try to understand the macro factors that drive policy–makers in setting the optimal framework for investments in renewable energy sources. The empirical analysis is performed on a large dataset of 136 countries and 41 variables observed in the time span 2000–2011. Countries analyzed include a sample of 12 SIDS (Bahrain, Cuba, Dominican Republic, Fiji Islands, Guyana, Haiti, Jamaica, Maldives, Mauritius, Papua New Guinea, Singapore, Trinidad and Tobago) distributed worldwide. Due to the large number of variables collected and their high degree of collinearity, the first step of the analysis concerns the implementation of a Principal Component Analysis in order to extract factors explaining the majority of variation of the original variables. In the second step, three different scenarios of modeling are designed to examine the key factors promoting RES investments. In a first scenario, we employ a pooled regression model, in the second a Fixed Effect model and, in the third, a Random Effect model is estimated. The main results of empirical analysis could be unexpected at first sight. They show, in fact, that SIDS are not on a energy sustainability path. As in the case of other developing countries, policy–makers prefer to use resources to improve economic aspects of development leaving behind issues related to the environmental protection, the use of RES and sustainability. In order to improve economic and environmental resilience of SIDS a synergy between local governments and international organizations to promote the investments in RES is needed. Moreover, an energy plan that clearly supports the generation of energy from RES is recommended. Finally policy–makers should strength their commitment in raising population's awareness toward a green energy generation. Such synergic interventions will allow SIDS to achieve a more sustainable development

  17. Effects of cigarette smoke exposure on nicotinic acetylcholine receptor subunits {alpha}7 and {beta}2 in the sudden infant death syndrome (SIDS) brainstem

    Energy Technology Data Exchange (ETDEWEB)

    Machaalani, Rita, E-mail: rita.machaalani@sydney.edu.au [Department of Medicine, The University of Sydney, NSW 2006 (Australia); Bosch Institute, The University of Sydney, NSW 2006 (Australia); The Children' s Hospital at Westmead, NSW 2145 (Australia); Say, Meichien [Department of Medicine, The University of Sydney, NSW 2006 (Australia); Bosch Institute, The University of Sydney, NSW 2006 (Australia); Waters, Karen A. [Department of Medicine, The University of Sydney, NSW 2006 (Australia); Bosch Institute, The University of Sydney, NSW 2006 (Australia); The Children' s Hospital at Westmead, NSW 2145 (Australia)

    2011-12-15

    It is postulated that nicotine, as the main neurotoxic constituent of cigarette smoke, influences SIDS risk through effects on nicotinic acetylcholine receptors (nAChRs) in brainstem nuclei that control respiration and arousal. This study compared {alpha}7 and {beta}2 nAChR subunit expression in eight nuclei of the caudal and rostral medulla and seven nuclei of the pons between SIDS (n = 46) and non-SIDS infants (n = 14). Evaluation for associations with known SIDS risk factors included comparison according to whether infants had a history of exposure to cigarette smoke in the home, and stratification for sleep position and gender. Compared to non-SIDS infants, SIDS infants had significantly decreased {alpha}7 in the caudal nucleus of the solitary tract (cNTS), gracile and cuneate nuclei, with decreased {beta}2 in the cNTS and increased {beta}2 in the facial. When considering only the SIDS cohort: 1-cigarette smoke exposure was associated with increased {alpha}7 in the vestibular nucleus and increased {beta}2 in the rostral dorsal motor nucleus of the vagus, rNTS and Cuneate, 2-there was a gender interaction for {alpha}7 in the gracile and cuneate, and {beta}2 in the cNTS and rostral arcuate nucleus, and 3-there was no effect of sleep position on {alpha}7, but prone sleep was associated with decreased {beta}2 in three nuclei of the pons. In conclusion, SIDS infants demonstrate differences in expression of {alpha}7 and {beta}2 nAChRs within brainstem nuclei that control respiration and arousal, which is independent on prior history of cigarette smoke exposure, especially for the NTS, with additional differences for smoke exposure ({beta}2), gender ({alpha}7 and {beta}2) and sleep position ({beta}2) evident. -- Highlights: Black-Right-Pointing-Pointer The 'normal' response to smoke exposure is decreased {alpha}7 and {beta}2 in certain nuclei. Black-Right-Pointing-Pointer SIDS infants have decreased {alpha}7 in cNTS, Grac and Cun. Black

  18. Effects of cigarette smoke exposure on nicotinic acetylcholine receptor subunits α7 and β2 in the sudden infant death syndrome (SIDS) brainstem

    International Nuclear Information System (INIS)

    Machaalani, Rita; Say, Meichien; Waters, Karen A.

    2011-01-01

    It is postulated that nicotine, as the main neurotoxic constituent of cigarette smoke, influences SIDS risk through effects on nicotinic acetylcholine receptors (nAChRs) in brainstem nuclei that control respiration and arousal. This study compared α7 and β2 nAChR subunit expression in eight nuclei of the caudal and rostral medulla and seven nuclei of the pons between SIDS (n = 46) and non-SIDS infants (n = 14). Evaluation for associations with known SIDS risk factors included comparison according to whether infants had a history of exposure to cigarette smoke in the home, and stratification for sleep position and gender. Compared to non-SIDS infants, SIDS infants had significantly decreased α7 in the caudal nucleus of the solitary tract (cNTS), gracile and cuneate nuclei, with decreased β2 in the cNTS and increased β2 in the facial. When considering only the SIDS cohort: 1—cigarette smoke exposure was associated with increased α7 in the vestibular nucleus and increased β2 in the rostral dorsal motor nucleus of the vagus, rNTS and Cuneate, 2—there was a gender interaction for α7 in the gracile and cuneate, and β2 in the cNTS and rostral arcuate nucleus, and 3—there was no effect of sleep position on α7, but prone sleep was associated with decreased β2 in three nuclei of the pons. In conclusion, SIDS infants demonstrate differences in expression of α7 and β2 nAChRs within brainstem nuclei that control respiration and arousal, which is independent on prior history of cigarette smoke exposure, especially for the NTS, with additional differences for smoke exposure (β2), gender (α7 and β2) and sleep position (β2) evident. -- Highlights: ► The ‘normal’ response to smoke exposure is decreased α7 and β2 in certain nuclei. ► SIDS infants have decreased α7 in cNTS, Grac and Cun. ► SIDS infants have decreased β2 in cNTS and increased β2 in facial. ► The NTS is more sensitive to both α7 and β2 regulation in SIDS. ► Smoke exposure

  19. SID seeks sludge and foreign bodies in steam generator upper heads while CECIL robotically removes them

    International Nuclear Information System (INIS)

    Ashton, A.T.; Gay, J.

    1993-01-01

    The CECIL [Consolidated Edison Combined Inspection and Lancing] system provides a range of maintenance tools for cleaning the region between the tubesheet and the first support plate in steam generators. SID [Secondary Inspection Device] extends access to and inspection of the upper bundle region. Work is being done to combine CECIL and SID technology to inspect and hydraulically clean the upper bundle. (Author)

  20. PROTEOMIC AND EPIGENOMIC MARKERS OF SEPSIS-INDUCED DELIRIUM (SID

    Directory of Open Access Journals (Sweden)

    Adonis eSfera

    2015-10-01

    Full Text Available In elderly population sepsis is one of the leading causes of intensive care unit (ICU admissions in the United States. Sepsis-induced delirium (SID is the most frequent cause of delirium in ICU (1. Together delirium and SID represent under recognized public health problems which place an increasing financial burden on the US health care system, currently estimated at 143 to 152 billion dollars per year (2. The interest in SID was recently reignited as it was demonstrated that, contrary to prior beliefs, cognitive deficits induced by this condition may be irreversible and lead to dementia (3-4. Conversely, it is construed that diagnosing SID early or mitigating its full blown manifestations may preempt geriatric cognitive disorders. Biological markers specific for sepsis and SID would facilitate the development of potential therapies, monitor the disease process and at the same time enable elderly individuals to make better informed decisions regarding surgeries which may pose the risk of complications, including sepsis and delirium.This article proposes a battery of peripheral blood markers to be used for diagnostic and prognostic purposes in sepsis and SID. Though each individual marker may not be specific enough, we believe that together as a battery they may achieve the necessary accuracy to answer two important questions: who may be vulnerable to the development of sepsis, and who may develop SID and irreversible cognitive deficits following sepsis?

  1. Sudden infant death syndrome (SIDS): a time lag factor.

    Science.gov (United States)

    Reid, G M

    1991-02-01

    A time lag factor of about five days has been identified in an increased incidence of SIDS in relation to a cold day. Sudden exposure to chilling appeared to trigger skeletal muscle weakness and renal failure about five days later in a man found to have only 25% of normal carnitine palmitoyl transferase (CPT) activity in biopsied skeletal muscle. White Muscle Disease is a muscular dystrophy in young ruminants which appears about five days after turnout to pasture in the weaned ruminant raised on a diet deficient in vitamin E and selenium (VESD). Pasture has high levels of linoleic and linolenic acid (high PUFA diet) which are modified by developing rumen bacteria. Corbucci investigated the effects of circulatory shock (cardiogenic) on skeletal muscle mitochondrial activity in humans. Cytochrome oxidase activity fell markedly and, in particular, the capacity to oxidase palmitoyl carnitine was greatly reduced. He considered a consequence of this disorder was sequestration of carnitine as acyl carnitine which could not be recycled. Unusual acyl carnitines have been identified in six out of 13 SIDS victims in a USA group. In Finland, researchers identified a rise in SIDS incidence (mostly found in the prone position) after great and rapid temperature changes. Foster found a relationship between 1984 SIDS incidence and the incidence of goitre in World War I troops.

  2. Sudden Ionospheric Disturbances (SID)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sudden ionospheric disturbances (SID) are caused by solar flare enhanced X-rays in the 1 to 10 angstrom range. Solar flares can produce large increases of ionization...

  3. Myths and Facts about SIDS and Safe Infant Sleep

    Science.gov (United States)

    ... Myths and Facts About SIDS and Safe Infant Sleep Page Content Myth: Babies can “catch” SIDS. Fact: ... sleep environment for your baby. Myth: Babies who sleep on their backs will choke if they spit ...

  4. SIDS-toADF File Mapping Manual

    Science.gov (United States)

    McCarthy, Douglas; Smith, Matthew; Poirier, Diane; Smith, Charles A. (Technical Monitor)

    2002-01-01

    The "CFD General Notation System" (CGNS) consists of a collection of conventions, and conforming software, for the storage and retrieval of Computational Fluid Dynamics (CFD) data. It facilitates the exchange of data between sites and applications, and helps stabilize the archiving of aerodynamic data. This effort was initiated in order to streamline the procedures in exchanging data and software between NASA and its customers, but the goal is to develop CGNS into a National Standard for the exchange of aerodynamic data. The CGNS development team is comprised of members from Boeing Commercial Airplane Group, NASA-Ames, NASA-Langley, NASA-Lewis, McDonnell-Douglas Corporation (now Boeing-St. Louis), Air Force-Wright Lab., and ICEM-CFD Engineering. The elements of CGNS address all activities associated with the storage of data on external media and its movement to and from application programs. These elements include: 1) The Advanced Data Format (ADF) Database manager, consisting of both a file format specification and its I/O software, which handles the actual reading and writing of data from and to external storage media; 2) The Standard Interface Data Structures (SIDS), which specify the intellectual content of CFD data and the conventions governing naming and terminology; 3) The SIDS-to-ADF File Mapping conventions, which specify the exact location where the CFD data defined by the SIDS is to be stored within the ADF file(s); and 4) The CGNS Mid-level Library, which provides CFD-knowledgeable routines suitable for direct installation into application codes. The SIDS-toADF File Mapping Manual specifies the exact manner in which, under CGNS conventions, CFD data structures (the SIDS) are to be stored in (i.e., mapped onto) the file structure provided by the database manager (ADF). The result is a conforming CGNS database. Adherence to the mapping conventions guarantees uniform meaning and location of CFD data within ADF files, and thereby allows the construction of

  5. Microbiome-Gut-Brain Axis: A Pathway for Improving Brainstem Serotonin Homeostasis and Successful Autoresuscitation in SIDS-A Novel Hypothesis.

    Science.gov (United States)

    Praveen, Vijayakumar; Praveen, Shama

    2016-01-01

    Sudden infant death syndrome (SIDS) continues to be a major public health issue. Following its major decline since the "Back to Sleep" campaign, the incidence of SIDS has plateaued, with an annual incidence of about 1,500 SIDS-related deaths in the United States and thousands more throughout the world. The etiology of SIDS, the major cause of postneonatal mortality in the western world, is still poorly understood. Although sleeping in prone position is a major risk factor, SIDS continues to occur even in the supine sleeping position. The triple-risk model of Filiano and Kinney emphasizes the interaction between a susceptible infant during a critical developmental period and stressor/s in the pathogenesis of SIDS. Recent evidence ranges from dysregulated autonomic control to findings of altered neurochemistry, especially the serotonergic system that plays an important role in brainstem cardiorespiratory/thermoregulatory centers. Brainstem serotonin (5-HT) and tryptophan hydroxylase-2 (TPH-2) levels have been shown to be lower in SIDS, supporting the evidence that defects in the medullary serotonergic system play a significant role in SIDS. Pathogenic bacteria and their enterotoxins have been associated with SIDS, although no direct evidence has been established. We present a new hypothesis that the infant's gut microbiome, and/or its metabolites, by its direct effects on the gut enterochromaffin cells, stimulates the afferent gut vagal endings by releasing serotonin (paracrine effect), optimizing autoresuscitation by modulating brainstem 5-HT levels through the microbiome-gut-brain axis, thus playing a significant role in SIDS during the critical period of gut flora development and vulnerability to SIDS. The shared similarities between various risk factors for SIDS and their relationship with the infant gut microbiome support our hypothesis. Comprehensive gut-microbiome studies are required to test our hypothesis.

  6. Maternal and obstetrical predictors of sudden infant death syndrome (SIDS).

    Science.gov (United States)

    Friedmann, Isabel; Dahdouh, Elias M; Kugler, Perlyne; Mimran, Gracia; Balayla, Jacques

    2017-10-01

    Public Health initiatives, such as the "Safe to Sleep" campaign, have traditionally targeted infants' risk factors for the prevention of Sudden Infant Death Syndrome (SIDS). However, controversy remains regarding maternal and obstetrical risk factors for SIDS. In our study, we sought out to determine both modifiable and non-modifiable obstetrical and maternal risk factors associated with SIDS. We conducted a population-based cohort study using the CDC's Linked Birth-Infant Death data from the United States for the year 2010. The impact of several obstetrical and maternal risk factors on the risk of overall infant mortality and SIDS was estimated using unconditional regression analysis, adjusting for relevant confounders. Our cohort consisted of 4,007,105 deliveries and 24,174 infant deaths during the first year of life, of which 1991 (8.2%) were due to SIDS. Prominent risk factors for SIDS included (OR [95% CI]): black race, 1.89 [1.68-2.13]; maternal smoking, 3.56 [3.18-3.99]; maternal chronic hypertension, 1.73 [1.21-2.48]; gestational hypertension, 1.51 [1.23-1.87]; premature birth <37 weeks, 2.16 [1.82-2.55]; IUGR, 2.46 [2.14-2.82]; and being a twin, 1.81 [1.43-2.29], p < 0.0001. Relative to a cohort of infants who died of other causes, risk factors with a predilection for SIDS were maternal smoking, 2.48 [2.16-2.83] and being a twin, 1.52 [1.21-1.91], p < 0.0001. Conclusions for practice: While certain socio-demographic and gestational characteristics are important risk factors, maternal smoking remains the strongest prenatal modifiable risk factor for SIDS. We recommend the continuation of Public Health initiatives that promote safe infant sleeping practices and smoking cessation during and after pregnancy.

  7. Simulating SiD Calorimetry: Software Calibration Procedures and Jet Energy Resolution

    International Nuclear Information System (INIS)

    Cassell, R.

    2009-01-01

    Simulated calorimeter performance in the SiD detector is examined. The software calibration procedures are described, as well as the perfect pattern recognition PFA reconstruction. Performance of the SiD calorimeters is summarized with jet energy resolutions from calorimetry only, perfect pattern recognition and the SiD PFA algorithm. Presented at LCWS08(1). Our objective is to simulate the calorimeter performance of the SiD detector, with and without a Particle Flow Algorithm (PFA). Full Geant4 simulations using SLIC(2) and the SiD simplified detector geometry (SiD02) are used. In this geometry, the calorimeters are represented as layered cylinders. The EM calorimeter is Si/W, with 20 layers of 2.5mm W and 10 layers of 5mm W, segmented in 3.5 x 3.5mm 2 cells. The HAD calorimeter is RPC/Fe, with 40 layers of 20mm Fe and a digital readout, segmented in 10 x 10mm 2 cells. The barrel detectors are layered in radius, while the endcap detectors are layered in z(along the beam axis)

  8. Solar Features - Solar Flares - SIDS

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A Sudden Ionospheric Disturbance (SID) is any of several radio propagation anomalies due to ionospheric changes resulting from solar or geophysical events.

  9. The Role of Respiratory Infection in Sudden Infant Death Syndrome (SIDS

    Directory of Open Access Journals (Sweden)

    Mage David T.

    2016-06-01

    Full Text Available Introduction: The Sudden Infant Death Syndrome (SIDS is not likely to be explained by a currently measureable presence in all cases and absence in controls, as otherwise it would have been solved already. Indeed, any proposed physiological model for SIDS causation must explain the constant mathematical and statistical properties of SIDS age and gender. We have shown previously that SIDS are characterized by a common 4-parameter lognormal age distribution sparing neonatal infants, by a nominal 50% male excess, and by a higher rate in winter than summer. We test now whether SIDS is closely related to a fulminating prodromal Acute Respiratory Infection (ARI by a common increasing rate with the infants increasing Live Birth Order (LBO, all remaining the same, independent of the change in preferred sleeping positions of the infants, prone or supine.

  10. Reclassification of SIDS cases--a need for adjustment of the San Diego classification?

    DEFF Research Database (Denmark)

    Jensen, Lisbeth Lund; Rohde, Marianne Cathrine; Banner, Jytte

    2012-01-01

    , now representing 38% of the cases; category IB SIDS constituted 10 (20%) and II SIDS 39 (80%) of the SIDS cases. No cases were classified as IA SIDS. Two hundred eighteen infant cases were identified from the files of the Department of Forensic Medicine, Aarhus University, Denmark over a 16-year....... None of the cases met the criteria for IA SIDS. Problems arose in assessing cases with failure to thrive, fever, and possible asphyxia. Modifications to the San Diego subclassifications might improve the consistency of categorizing these cases....

  11. Sarcomeric gene mutations in sudden infant death syndrome (SIDS).

    Science.gov (United States)

    Brion, Maria; Allegue, Catarina; Santori, Montserrat; Gil, Rocio; Blanco-Verea, Alejandro; Haas, Cordula; Bartsch, Christine; Poster, Simone; Madea, Burkhard; Campuzano, Oscar; Brugada, Ramon; Carracedo, Angel

    2012-06-10

    In developed countries, sudden infant death syndrome (SIDS) represents the most prevalent cause of death in children between 1 month and 1 year of age. SIDS is a diagnosis of exclusion, a negative autopsy which requires the absence of structural organ disease. Although investigators have confirmed that a significant percentage of SIDS cases are actually channelopathies, no data have been made available as to whether other sudden cardiac death-associated diseases, such as hypertrophic cardiomyopathy (HCM), could be responsible for some cases of SIDS. The presence of a genetic mutation in the sarcomeric protein usually affects the force of contraction of the myocyte, whose weakness is compensated with progressive hypertrophy and disarray. However, it is unclear whether in the most incipient forms, that is, first years of life, the lack of these phenotypes still confers a risk of arrhythmogenesis. The main goal of the present study is to wonder whether genetic defects in the sarcomeric proteins, previously associated with HCM, could be responsible for SIDS. We have analysed 286 SIDS cases for the most common genes implicated in HCM in adults. A total of 680 mutations localised in 16 genes were analysed by semi-automated matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDITOF-MS) using the Sequenom MassARRAY(®) System. Ten subjects with completely normal hearts showed mutated alleles at nine of the genetic variants analysed, and one additional novel mutation was detected by conventional sequencing. Therefore, a genetic mutation associated with HCM may cause sudden cardiac death in the absence of an identifiable phenotype. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  12. Interactions of infectious symptoms and modifiable risk factors in sudden infant death syndrome. The Nordic Epidemiological SIDS study

    DEFF Research Database (Denmark)

    Helweg-Larsen, K; Banner, Jytte; Oyen, N

    1999-01-01

    The aim of the study was to investigate the effect of infection on sudden infant death syndrome (SIDS) and to analyse whether modifiable risk factors of SIDS, prone sleeping, covered head and smoking act as effect modifiers. In a consecutive multicentre case-control study of SIDS in Denmark, Norway...... regression. Significantly more cases than controls presenting symptoms of infectious diseases during the last week and/or last day were treated with antibiotics and had been seen by a physician. The finding is consistent with the hypothesis of an infectious mechanism in SIDS induced by local microorganism......, prone sleeping, head covered or parental smoking, was far greater than the sum of each individual factor. These risk factors thus modify the dangerousness of infection in infancy....

  13. A “wear and tear” hypothesis to explain Sudden Infant Death Syndrome (SIDS

    Directory of Open Access Journals (Sweden)

    Eran Elhaik

    2016-10-01

    Full Text Available Sudden Infant Death Syndrome (SIDS is the leading cause of death in USA infants under one year of age accounting for approximately 2,700 deaths per year. Although formally SIDS dates back at least 2,000 years and was even mentioned in the Hebrew Bible (Kings 3:19 its etiology remains unexplained prompting the CDC to initiate a sudden unexpected infant death case registry in 2010. Due to their total dependence, the ability of the infant to allostatically regulate stressors and stress responses shaped by genetic and environmental factors is severely constrained. We propose that SIDS is the result of cumulative painful, stressful, or traumatic exposures that begin in utero and tax neonatal regulatory systems incompatible with allostasis. We also identify several putative biochemical mechanisms involved in SIDS. We argue that the important characteristics of SIDS, namely male predominance (60:40, the significantly different SIDS rate in USA Hispanics (80% lower compared to whites, 50% of cases occurring between 7.6 and 17.6 weeks after birth with only 10% after 24.7 weeks, and seasonal variation with most cases occurring during winter, are all associated with common environmental stressors, such as neonatal circumcision and seasonal illnesses. We predict that neonatal circumcision is associated with hypersensitive to pain and decreased heart rate variability which increase the risk for SIDS. We also predict that neonatal male circumcision will account for the SIDS gender bias and that cultures that practice high male circumcision rates, like USA whites, will have higher SIDS rates compared to cultures with lower circumcision rates. SIDS rates will also be higher in USA states where Medicaid covers circumcision and lower among cultures that do not practice neonatal circumcision and/or cannot afford to pay for circumcision. We last predict that winter-born premature infants who are circumcised will be at higher risk of SIDS compared to infants who

  14. Soaking RNAi in Bombyx mori BmN4-SID1 Cells Arrests Cell Cycle Progression

    Science.gov (United States)

    Mon, Hiroaki; Li, Zhiqing; Kobayashi, Isao; Tomita, Shuichiro; Lee, JaeMan; Sezutsu, Hideki; Tamura, Toshiki; Kusakabe, Takahiro

    2013-01-01

    RNA interference (RNAi) is an evolutionarily conserved mechanism for sequence-specific gene silencing. Previously, the BmN4-SID1 cell expressing Caenorhabditis ele gans SID-1 was established, in which soaking RNAi could induce effective gene silencing. To establish its utility, 6 cell cycle progression related cDNAs, CDK1, MYC, MYB, RNRS, CDT1, and GEMININ, were isolated from the silkworm, Bombyx mori L. (Lepidoptera: Bombycidae), and their expressions were further silenced by soaking RNAi in the BmN4-SID1 cells. The cell cycle progression analysis using flow cytometer demonstrated that the small amount of double stranded RNA was enough to arrest cell cycle progression at the specific cell phases. These data suggest that RNAi in the BmN4-SID1 cells can be used as a powerful tool for loss-of-function analysis of B. mori genes. PMID:24773378

  15. Inhibition of the Flavin-Dependent Monooxygenase Siderophore A (SidA) Blocks Siderophore Biosynthesis and Aspergillus fumigatus Growth.

    Science.gov (United States)

    Martín Del Campo, Julia S; Vogelaar, Nancy; Tolani, Karishma; Kizjakina, Karina; Harich, Kim; Sobrado, Pablo

    2016-11-18

    Aspergillus fumigatus is an opportunistic fungal pathogen and the most common causative agent of fatal invasive mycoses. The flavin-dependent monooxygenase siderophore A (SidA) catalyzes the oxygen and NADPH dependent hydroxylation of l-ornithine (l-Orn) to N 5 -l-hydroxyornithine in the biosynthetic pathway of hydroxamate-containing siderophores in A. fumigatus. Deletion of the gene that codes for SidA has shown that it is essential in establishing infection in mice models. Here, a fluorescence polarization high-throughput assay was used to screen a 2320 compound library for inhibitors of SidA. Celastrol, a natural quinone methide, was identified as a noncompetitive inhibitor of SidA with a MIC value of 2 μM. Docking experiments suggest that celastrol binds across the NADPH and l-Orn pocket. Celastrol prevents A. fumigatus growth in blood agar. The addition of purified ferric-siderophore abolished the inhibitory effect of celastrol. Thus, celastrol inhibits A. fumigatus growth by blocking siderophore biosynthesis through SidA inhibiton.

  16. Moving beyond LCOE: impact of various financing methods on PV profitability for SIDS

    International Nuclear Information System (INIS)

    Tao, Jacqueline Yujia; Finenko, Anton

    2016-01-01

    Small island developing states (SIDS) have some of the highest electricity tariffs globally. Renewable energy (RE) technologies could thus have reached grid parity in various SIDS. Furthermore, the abundance of resources such as solar and wind provides ample potential for SIDS to switch from high cost diesel generators to renewables. Despite favourable conditions, RE remains a largely underinvested sector in these regions. This paper aims to undercover the reasons why grid parity does not necessary translate into private sector investments in RE. With a focus on SIDS, this paper presents an evidence that achieving grid parity based on LCOE estimates is an incomplete benchmark for decision making in the power generation industry. In particular, LCOE and grid parity do not take into account financing constraints of RE projects which are often more pronounced compared to conventional forms of power generation. This paper thus presents the business perspective of RE projects, by employing a discounted cashflow model that includes various profitability metrics and effects of taxation and depreciation. The study shows that financing conditions exert strong influence on the economic feasibility of solar projects, both in LCOE terms and profitability terms. Thus, key policies should be targeted at improving financing conditions to ensure mobilization of private sector finances in solar PV. - Highlights: • LCOE estimates do not accurately represent financial viability for project developers • Access to low cost financing is critical for solar proliferation in SIDS • Fluctuations in electricity tariffs is the main source of risk for solar PV developers in SIDS, which could be mitigated by PPA arrangements • Access to grid, high corporate tax rates, and lack of information transparency are key barriers for solar PV developers

  17. Hazardous Waste/Mixed Waste Treatment Building Safety Information Document (SID)

    International Nuclear Information System (INIS)

    Fatell, L.B.; Woolsey, G.B.

    1993-01-01

    This Safety Information Document (SID) provides a description and analysis of operations for the Hazardous Waste/Mixed Waste Disposal Facility Treatment Building (the Treatment Building). The Treatment Building has been classified as a moderate hazard facility, and the level of analysis performed and the methodology used are based on that classification. Preliminary design of the Treatment Building has identified the need for two separate buildings for waste treatment processes. The term Treatment Building applies to all these facilities. The evaluation of safety for the Treatment Building is accomplished in part by the identification of hazards associated with the facility and the analysis of the facility's response to postulated events involving those hazards. The events are analyzed in terms of the facility features that minimize the causes of such events, the quantitative determination of the consequences, and the ability of the facility to cope with each event should it occur. The SID presents the methodology, assumptions, and results of the systematic evaluation of hazards associated with operation of the Treatment Building. The SID also addresses the spectrum of postulated credible events, involving those hazards, that could occur. Facility features important to safety are identified and discussed in the SID. The SID identifies hazards and reports the analysis of the spectrum of credible postulated events that can result in the following consequences: Personnel exposure to radiation; Radioactive material release to the environment; Personnel exposure to hazardous chemicals; Hazardous chemical release to the environment; Events leading to an onsite/offsite fatality; and Significant damage to government property. The SID addresses the consequences to the onsite and offsite populations resulting from postulated credible events and the safety features in place to control and mitigate the consequences

  18. Hazardous Waste/Mixed Waste Treatment Building Safety Information Document (SID)

    Energy Technology Data Exchange (ETDEWEB)

    Fatell, L.B.; Woolsey, G.B.

    1993-04-15

    This Safety Information Document (SID) provides a description and analysis of operations for the Hazardous Waste/Mixed Waste Disposal Facility Treatment Building (the Treatment Building). The Treatment Building has been classified as a moderate hazard facility, and the level of analysis performed and the methodology used are based on that classification. Preliminary design of the Treatment Building has identified the need for two separate buildings for waste treatment processes. The term Treatment Building applies to all these facilities. The evaluation of safety for the Treatment Building is accomplished in part by the identification of hazards associated with the facility and the analysis of the facility`s response to postulated events involving those hazards. The events are analyzed in terms of the facility features that minimize the causes of such events, the quantitative determination of the consequences, and the ability of the facility to cope with each event should it occur. The SID presents the methodology, assumptions, and results of the systematic evaluation of hazards associated with operation of the Treatment Building. The SID also addresses the spectrum of postulated credible events, involving those hazards, that could occur. Facility features important to safety are identified and discussed in the SID. The SID identifies hazards and reports the analysis of the spectrum of credible postulated events that can result in the following consequences: Personnel exposure to radiation; Radioactive material release to the environment; Personnel exposure to hazardous chemicals; Hazardous chemical release to the environment; Events leading to an onsite/offsite fatality; and Significant damage to government property. The SID addresses the consequences to the onsite and offsite populations resulting from postulated credible events and the safety features in place to control and mitigate the consequences.

  19. Time resolved spectroscopic investigation of SiD2 + D2: kinetic study

    Science.gov (United States)

    Al-Rubaiey, Najem A.; Walsh, Robin

    2017-03-01

    Silylenes (silanediyls) have made an important impact on organosilicon chemistry even if it is of more recent foundation than carbenes in organic chemistry and much less complete. These species are highly reactive intermediates. They play a central role in the chemical vapour deposition (CVD) of various silicon-containing thin films which have a technological importance in microelectronics as well as in the dry etching processes of silicon wafers. Spectroscopic methods have been developed to observe these species, a necessary pre-requisite to their direct monitoring. In this work, deuterated phenylsilane precursor, PhSiD3 was chosen for SiD2 because its analogue phenylsilane, PhSiH3 proved to be a good precursor for SiH2 and the high quality decay signals observed revealed that SiD2 be readily detected from PhSiD3 and that if other decomposition pathways (e.g. PhSiD + D2) are occurring, they do not effect measurements of the rate constants for SiD2. The absorption spectrum of SiD2 formed from the flash photolysis of a mixture of PhSiD3 and SF6 at 193nm were found in the region 17384-17391 cm-1 with strong band at 17387.07 cm-1. This single rotational line of pQ1 was chosen to monitor SiD2 removal. Time-resolved studies of SiD2 have been carried out to obtain rate constants for its bimolecular reactions with D2. The reactions were studied over the pressure range 5-100 Torr (in SF6 bath gas) at four temperatures in the range 298-498K. Single decay from 10 photolysis laser shots were averaged and found to give reasonable first-order kinetics fits. Second order kinetics were obtained by pressure dependence of the pseudo first order decay constants and substance D2 pressures within experimental error. The reaction was found to be weakly pressure dependent at all temperatures, consistent with a third-body mediated association process. In addition, SiH2+ H2 reaction is approximately ca. 60% faster than SiD2+D2 reaction. Theoretical extrapolations (using Lindemann

  20. Time resolved spectroscopic investigation of SiD2 + D2: kinetic study

    Directory of Open Access Journals (Sweden)

    Al-Rubaiey Najem A.

    2017-01-01

    Full Text Available Silylenes (silanediyls have made an important impact on organosilicon chemistry even if it is of more recent foundation than carbenes in organic chemistry and much less complete. These species are highly reactive intermediates. They play a central role in the chemical vapour deposition (CVD of various silicon-containing thin films which have a technological importance in microelectronics as well as in the dry etching processes of silicon wafers. Spectroscopic methods have been developed to observe these species, a necessary pre-requisite to their direct monitoring. In this work, deuterated phenylsilane precursor, PhSiD3 was chosen for SiD2 because its analogue phenylsilane, PhSiH3 proved to be a good precursor for SiH2 and the high quality decay signals observed revealed that SiD2 be readily detected from PhSiD3 and that if other decomposition pathways (e.g. PhSiD + D2 are occurring, they do not effect measurements of the rate constants for SiD2. The absorption spectrum of SiD2 formed from the flash photolysis of a mixture of PhSiD3 and SF6 at 193nm were found in the region 17384-17391 cm-1 with strong band at 17387.07 cm-1. This single rotational line of pQ1 was chosen to monitor SiD2 removal. Time-resolved studies of SiD2 have been carried out to obtain rate constants for its bimolecular reactions with D2. The reactions were studied over the pressure range 5-100 Torr (in SF6 bath gas at four temperatures in the range 298-498K. Single decay from 10 photolysis laser shots were averaged and found to give reasonable first-order kinetics fits. Second order kinetics were obtained by pressure dependence of the pseudo first order decay constants and substance D2 pressures within experimental error. The reaction was found to be weakly pressure dependent at all temperatures, consistent with a third-body mediated association process. In addition, SiH2+ H2 reaction is approximately ca. 60% faster than SiD2+D2 reaction. Theoretical extrapolations (using

  1. SiD Letter of Intent

    CERN Document Server

    Aihara, H.; Oreglia, M.; Berger, E.L.; Guarino, V.; Repond, J.; Weerts, H.; Xia, L.; Zhang, J.; Zhang, Q.; Srivastava, A.; Butler, J.M.; Goldstein, Joel; Velthuis, J.; Radeka, V.; Zhu, R.-Y.; Lutz, P.; de Roeck, A.; Elsener, K.; Gaddi, A.; Gerwig, H.; Grefe, C.; Klempt, W.; Linssen, L.; Schlatter, D.; Speckmayer, P.; Thom, J.; Yang, J.; Christian, D.C.; Cihangir, S.; Cooper, W.E.; Demarteau, M.; Fisk, H.E.; Garren, L.A.; Krempetz, K.; Kutschke, R.K.; Lipton, R.; Para, A.; Tschirhart, R.; Wenzel, H.; Yarema, R.; Grunewald, M.; Pankov, A.; U., Gomel State Tech.; Dutta, T.; Dauncey, P.D.; Balbuena, J.P.; Fleta, C.; Lozano, M.; Ullan, M.; Christian, G.B.; Faus-Golfe, A.; Fuster, J.; Lacasta, C.; Marinnas, C.; Vos, M.; Duarte, J.; Fernandez, M.; Gonzalez, J.; Jaramillo, R.; Lopez, Virto A.; Martinez-Eivero, C.; Moya, D.; Ruiz-Mimeno, A.; Vila, I.; Colledani, C.; Dorokhov, A.; Hu-Guo, C.; Winter, M.; Moortgat-Pick, G.; Onoprienko, D.V.; Kim, G.N.; Park, H.; Adloff, C.; Blaha, J.; Blaising, J.-J.; Cap, S.; Chefdeville, M.; Drancourt, C.; Espargiliare, A.; Gaglione, R.; Geffroy, N.; Jacquemier, J.; Karyotakis, Y.; Prast, J.; Vouters, G.; Gronberg, J.; Walston, S.; Wright, D.; Sawyer, L.; Laloum, M.; Ciobanu, C.; Chauveau, J.; Savoy-Navarro, A.; Andricek, L.; Moser, H.-G.; Cowan, R.f.; Fisher, P.; Yamamoto, R.K.; Kenney, ClMl; Boos, E.E.; Merkin, M.; Chen, S.; Chakraborty, D.; Dyshkant, A.; Hedin, D.; Zutshi, V.; Galkin, V.; D'Ascenzo, N.; Ossetski, D.; Saveliev, V.; Kapusta, F.; De Masi, R.; Vrba, V.; Lu, C.; McDonald, K.T.; Smith, A.J.S.; Bortoletto, D.; Coath, R.; Crooks, J.; Damerell, C.; Gibson, M.; Nichols, A.; Stanitzki, M.; Strube, J.; Turchetta, R.; Tyndel, M.; Weber, M.; Worm, S.; Zhang, Z.; Barklow, T.L.; Belymam, A.; Breidenbach, M.; Cassell, R.; Craddock, W.; Deaconu, C.; Dragone, A.; Graf, N.A.; Haller, G.; Herbst, R.; Hewett, J.L.; Jaros, J.A.; Johnson, A.S.; Kim, P.C.; MacFarlane, D.B.; Markiewicz, T.; Maruyama, T.; McCormick, J.; Moffeit, K.; Neal, H.A.; Nelson, T.K.; Oriunno, M.; Partridge, R.; Peskin, M.E.; Rizzo, T.G.; Rowson, P.; Su, D.; Woods, M.; Chakrabarti, S.; Dieguez, A.; Garrido, Ll.; Kaminski, J.; Conway, J.S.; Chertok, M.; Gunion, J.; Holbrook, B.; Lander, R.L.; Tripathi, S.M.; Fadeyev, V.; Schumm, B.A.; Oreglia, M.; Gill, J.; Nauenberg, U.; Oleinik, G.; Wagner, S.R.; Ranjan, K.; Shivpuri, R.; Varner, G.S.; Orava, R.; Van Kooten, R.; Bilki, B.; Charles, M.; Kim, T.J.; Mallik, U.; Norbeck, E.; Onel, Y.; Brau, B.P.; Willocq, S.; Taylor, G.N.; Riles, Keith; Yang, H.-J.; Kriske, R.; Cremaldi, L.; Rahmat, R.; Lastovicka-Medin, G.; Seidel, S.; Hildreth, M.D.; Wayne, M.; Brau, J.E.; Frey, R.; Sinev, N.; Strom, D.M.; Torrence, E.; Banda, Y.; Burrows, P.N.; Devetak, E.; Foster, B.; Lastovicka, T.; Li, Y.-M.; Nomerotski, A.; Riera-Babures, J.; Vilasis-Cardona, X.; Manly, S.; Adeva, B.; Iglesias Escudero, C.; Vazquez Regueiro, P.; Saborido Silva, J.J.; Gallas Torreira, A.; Gao, D.; Jie, W.; Jungfeng, Y.; Li, C.; Liu, S.; Liu, Y.; Sun, Y.; Wang, Q.; Yi, J.; Yonggang, W.; Zhao, Z.; De, K.; Farbin, A.; Park, S.; Smith, J.; White, A.P.; Yu, J.; Lou, X.C.; Abe, T.; Iwasaki, M.; Lubatti, H.J.; Band, H.R.; Feyzi, F.; Prepost, R.; Karchin, P.E.; Milstene, C.; Baltay, C.; Dhawan, S.; Kwon, Y.-J.

    2009-01-01

    Letter of intent describing SiD (Silicon Detector) for consideration by the International Linear Collider IDAG panel. This detector concept is founded on the use of silicon detectors for vertexing, tracking, and electromagnetic calorimetry. The detector has been cost-optimized as a general-purpose detector for a 500 GeV electron-positron linear collider.

  2. Low cerebrospinal fluid hypocretin levels during sudden infant death syndrome (SIDS) risk period.

    Science.gov (United States)

    Lancien, Marion; Inocente, Clara Odilia; Dauvilliers, Yves; Kugener, Beatrice; Scholz, Sabine; Raverot, Veronique; Lin, Jian-Sheng; Guyon, Aurore; Gustin, Marie-Paule; Franco, Patricia

    2017-05-01

    The temporal association between sudden infant death syndrome (SIDS) and sleep suggests that the arousability from sleep provides a protective mechanism for survival. Recently, the hypocretin system, which promotes wakefulness, has been implicated in SIDS, since it has been reported that SIDS victims have fewer hypocretin neurons than infants who have died from other causes. To understand the role of hypocretin in SIDS, it is essential to better understand how this system matures. The present study compared cerebrospinal fluid (CSF) hypocretin in children aged 2-6 months, which is the age of peak incidence for SIDS, to both younger and older children. Hypocretin levels were measured in CSF samples from 101 children who underwent a clinically relevant lumbar puncture. Children were separated into five age groups: 0-2 months, 2-6 months, 1-5 years, 5-10 years, and 10-18 years. Hypocretin levels were not significantly different between 1-5 years, 5-10 years, and 10-18 years. Therefore, these three groups were pooled into a single one (1-18 years) for further analysis. Between the 0-2 month, 2-6 month, and 1-18 year groups, a significant difference in CSF hypocretin levels existed (p = 0.001). Simple comparisons showed that CSF hypocretin levels in the 2-6 month age group were significantly lower than hypocretin levels in both the 0-2 month and 1-18 year group (p hypocretin levels were lower at the age of peak incidence for SIDS. This could underlie an increased vulnerability to SIDS at this specific age. Copyright © 2017. Published by Elsevier B.V.

  3. POSSIBLE ORIGIN OF RHIC R OUT/R SID HBT RESULTS

    International Nuclear Information System (INIS)

    PADULA, S.S.

    2002-01-01

    The effects of opacity of the nuclei together with a blackbody type of emission along the system history are considered as a means to explain the ratio R out /R sid observed by STAR and PHENIX collaborations at RHIC. Within our model, no flow is required to explain the data trend of this ratio for large surface emissivities

  4. POSSIBLE ORIGIN OF RHIC R OUT / R SID HBT RESULTS

    International Nuclear Information System (INIS)

    PADULA, S.

    2002-01-01

    The effects of opacity of the nuclei together with a blackbody type of emission along the system history are considered as a means to explain the ratio R out /R sid observed by STAR and PHENIX collaborations at RHIC. Within our model, no flow is required to explain the data trend of this ratio for large surface emissivities

  5. Common SIDS and SUID Terms and Definitions

    Science.gov (United States)

    ... media links Common SIDS and SUID Terms and Definitions Page Content Health care providers and others may ... NICHD Home Accessibility NICHD Contact Disclaimer NICHD Accounts: Facebook Twitter Pinterest YouTube NIH...Turning Discovery Into Health ® ...

  6. Structural basis for Rab1 de-AMPylation by the Legionella pneumophila effector SidD.

    Directory of Open Access Journals (Sweden)

    Yang Chen

    Full Text Available The covalent attachment of adenosine monophosphate (AMP to proteins, a process called AMPylation (adenylylation, has recently emerged as a novel theme in microbial pathogenesis. Although several AMPylating enzymes have been characterized, the only known virulence protein with de-AMPylation activity is SidD from the human pathogen Legionella pneumophila. SidD de-AMPylates mammalian Rab1, a small GTPase involved in secretory vesicle transport, thereby targeting the host protein for inactivation. The molecular mechanisms underlying Rab1 recognition and de-AMPylation by SidD are unclear. Here, we report the crystal structure of the catalytic region of SidD at 1.6 Å resolution. The structure reveals a phosphatase-like fold with additional structural elements not present in generic PP2C-type phosphatases. The catalytic pocket contains a binuclear metal-binding site characteristic of hydrolytic metalloenzymes, with strong dependency on magnesium ions. Subsequent docking and molecular dynamics simulations between SidD and Rab1 revealed the interface contacts and the energetic contribution of key residues to the interaction. In conjunction with an extensive structure-based mutational analysis, we provide in vivo and in vitro evidence for a remarkable adaptation of SidD to its host cell target Rab1 which explains how this effector confers specificity to the reaction it catalyses.

  7. SiD Linear Collider Detector R&D, DOE Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Brau, James E. [Univ. of Oregon, Eugene, OR (United States); Demarteau, Marcel [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-05-15

    The Department of Energy’s Office of High Energy Physics supported the SiD university detector R&D projects in FY10, FY11, and FY12 with no-cost extensions through February, 2015. The R&D projects were designed to advance the SiD capabilities to address the fundamental questions of particle physics at the International Linear Collider (ILC): • What is the mechanism responsible for electroweak symmetry breaking and the generation of mass? • How do the forces unify? • Does the structure of space-time at small distances show evidence for extra dimensions? • What are the connections between the fundamental particles and forces and cosmology? Silicon detectors are used extensively in SiD and are well-matched to the challenges presented by ILC physics and the ILC machine environment. They are fast, robust against machine-induced background, and capable of very fine segmentation. SiD is based on silicon tracking and silicon-tungsten sampling calorimetry, complemented by powerful pixel vertex detection, and outer hadronic calorimetry and muon detection. Radiation hard forward detectors which can be read out pulse by pulse are required. Advanced calorimetry based on a particle flow algorithm (PFA) provides excellent jet energy resolution. The 5 Tesla solenoid is outside the calorimeter to improve energy resolution. PFA calorimetry requires fine granularity for both electromagnetic and hadronic calorimeters, leading naturally to finely segmented silicon-tungsten electromagnetic calorimetry. Since silicon-tungsten calorimetry is expensive, the detector architecture is compact. Precise tracking is achieved with the large magnetic field and high precision silicon microstrips. An ancillary benefit of the large magnetic field is better control of the e⁺e⁻ pair backgrounds, permitting a smaller radius beampipe and improved impact parameter resolution. Finally, SiD is designed with a cost constraint in mind. Significant advances and new capabilities have been made and

  8. Aspergillus fumigatus SidA is a highly specific ornithine hydroxylase with bound flavin cofactor.

    Science.gov (United States)

    Chocklett, Samuel W; Sobrado, Pablo

    2010-08-10

    Ferrichrome is a hydroxamate-containing siderophore produced by the pathogenic fungus Aspergillus fumigatus under iron-limiting conditions. This siderophore contains N(5)-hydroxylated l-ornithines essential for iron binding. A. fumigatus siderophore A (Af SidA) catalyzes the flavin- and NADPH-dependent hydroxylation of l-ornithine in ferrichrome biosynthesis. Af SidA was recombinantly expressed and purified as a soluble tetramer and is the first member of this class of flavin monooxygenases to be isolated with a bound flavin cofactor. The enzyme showed typical saturation kinetics with respect to l-ornithine while substrate inhibition was observed at high concentrations of NADPH and NADH. Increasing amounts of hydrogen peroxide were measured as a function of reduced nicotinamide coenzyme concentration, indicating that inhibition was caused by increased uncoupling. Af SidA is highly specific for its amino acid substrate, only hydroxylating l-ornithine. An 8-fold preference in the catalytic efficiency was determined for NADPH compared to NADH. In the absence of substrate, Af SidA can be reduced by NADPH, and a C4a-(hydro)peroxyflavin intermediate is observed. The decay of this intermediate is accelerated by l-ornithine binding. This intermediate was only stabilized by NADPH and not by NADH, suggesting a role for NADP(+) in the stabilization of intermediates in the reaction of Af SidA. NADP(+) is a competitive inhibitor with respect to NADPH, demonstrating that Af SidA forms a ternary complex with NADP(+) and l-ornithine during catalysis. The data suggest that Af SidA likely proceeds by a sequential kinetic mechanism.

  9. HCUP State Inpatient Databases (SID) - Restricted Access File

    Data.gov (United States)

    U.S. Department of Health & Human Services — The State Inpatient Databases (SID) contain the universe of hospital inpatient discharge abstracts in States participating in HCUP that release their data through...

  10. An Acute Respiratory Infection of a Physiologically Anemic Infant is a More Likely Cause of SIDS than Neurological Prematurity

    Directory of Open Access Journals (Sweden)

    E. Maria Donner

    2016-08-01

    Full Text Available Introduction: The cause of the Sudden Infant Death Syndrome (SIDS is perhaps the oldest of unsolved mysteries of medicine, possibly dating back to Exodus in Biblical times when Egyptian children died in their sleep as if from a plague. It occurs when infants die unexpectedly with no sufficient cause of death found in a forensic autopsy including death scene investigation and review of medical history. That SIDS is an X-linked recessive death from infectious respiratory disease of a physiologically anemic infant and not a simple anomalous cardiac or neurological condition is an extraordinary claim that requires extraordinary evidence. If it were by a simple cause it would have been solved already with over 11,000 papers on SIDS listed now in PUBMED. Any proposed cause of SIDS must explain: 1 its 50% excess male death rate; 2 its 4-parameter lognormal distribution of ages at death; 3 its winter maxima and summer minima; and 4 its increasing rate with livebirth order.Methods: From extensive SIDS vital statistics data and published epidemiologic studies, we developed probability models to explain the mathematical behavior of SIDS meeting the four constraints mentioned above. We then compare these SIDS properties to infant death from Acute Respiratory Infection (ARI, and infant death from Encephalopathy, Unspecified (EU.Results: Comparisons show that SIDS are congruent with ARI and are not consistent with EU, and that these probability models not only fit the SIDS data but they also predict and fit the male fraction of all infant and child mortality from birth through the first 5 years of their life.Conclusions: SIDS are not rejected as an X-linked disease involving ARI and are not explained by a triple risk model that has been commonly accepted by the SIDS medical community as implicating a neurological causation process in a subset of SIDS.

  11. Ways To Reduce the Risk of SIDS and Other Sleep-Related Causes of Infant Death

    Science.gov (United States)

    ... SIDS and Other Sleep-Related Causes of Infant Death Page Content Research shows that there are several ... SIDS and other sleep-related causes of infant death: The actions listed here and in Safe to ...

  12. Chlamydia and sudden infant death syndrome. A study of 166 SIDS and 30 control cases

    DEFF Research Database (Denmark)

    Banner, Jytte; Lundemose, A G; Gregersen, M

    1990-01-01

    .04). Chlamydia trachomatis is an agent of pneumonia in 1-4 month-old infants who have acquired the disease from an infected cervix during birth, but other chlamydia species are also capable of causing pneumonia. The lung sections of the 32 chlamydia positive SIDS cases did not show typical histological signs......Chlamydia inclusions could be demonstrated by an immunofluorescence assay in formalin-fixed lung sections in 32 of 166 cases (19.4%) of Sudden Infant Death Syndrome (SIDS) and in the lungs of only 1 of 30 infants with a known cause of death (3.3%). The difference is statistically significant (P = 0...... of pneumonia. Even though chlamydia inclusions were detected in the lungs of 32 SIDS cases a causal relation between chlamydia infection and SIDS could not be demonstrated....

  13. Use of Elements of the Stewart Model (Strong Ion Approach) - SID3, SID4, Atot/A-, SIDe and SIG for the Diagnostics of Respiratory Acidosis in Brachycephalic Dogs.

    Science.gov (United States)

    Sławuta, P; Sapikowski, G; Sobieraj, B

    2016-09-01

    Buffer systems of blood and tissues, which have the ability to bind with and give up hydrogen ions, participate in maintaining the acid-base balance (ABB) of the organism. According to the classic model, the system of carbonic acid and bicarbonates, where the first component serves the role of an acid and the second a base, determines plasma pH. The so-called Stewart model, which assumes that ions in blood serum can be separated into completely dissociated - nonbuffer and not dissociated - buffer ions which may give up or accept H+ions, also describes the ABB of the organism. The goal of the study was to find out whether, during respiratory acidosis, the values of SID3, SID4, Atot/A-, SIDe and SIG change. The study was carried out on 60 adult dogs of the boxer breed (32 males and 28 females) in which, on the basis of an arterial blood test, respiratory acidosis was found. A strong overgrowth of the soft palate tissue requiring a surgical correction was the cause of the ABB disorder. Prior to surgery and on the 14th day after the surgery, venous and arterial blood was drawn from each dog. ABB parameters were determined in the arterial blood sample: the blood pH, pCO2 and HCO3-. In the venous blood, concentration of Na+, K+, Cl-, lactate-, albumins, and Pinorganic was determined. On the basis of the obtained data, the values of SID3, SID4, SIDe, A- and SIG, before and after the surgery, were calculated. In spite of the fact that the average concentration of ions, albumins, Pinorganic and lactate in the blood serum of dogs before and after the surgical procedure was similar and within the physiological norms, the values of SID3, SIDe and SIG, calculated on the basis of the former, displayed statistically significant differences. On the basis of the results obtained, it can be stated that the values of SID3, SIDe and SIG change during respiratory acidosis and may be helpful in the diagnostics of ABB disorders in brachycephalic dogs.

  14. Maori Men and the Grief of SIDS

    Science.gov (United States)

    Edwards, Shane; McCreanor, Tim; Ormsby, Manga; Tuwhangai, Nick; Tipene-Leach, David

    2009-01-01

    The loss of a baby is always hard to cope with and the grieving process is likely to be difficult. Interventions to work with Sudden Infant Death Syndrome (SIDS) families have improved grieving outcomes for many but the needs of Maori fathers are not well understood or catered to by existing services. This article presents narrative data from…

  15. Possible origin of RHIC R{sub out}/R{sub sid} HBT results

    Energy Technology Data Exchange (ETDEWEB)

    Padula, Sandra S

    2003-03-10

    The effects of opacity of the nuclei together with a blackbody type of emission along the system history are considered as a means to explain the ratio R{sub out}/R{sub sid} observed by STAR and PHENIX collaborations at RHIC. Within our model, no flow is required to explain the data trend of this ratio for large surface emissivities.

  16. Seychelles, a vulnerable or resilient SIDS? A local perspective

    Directory of Open Access Journals (Sweden)

    Dean Philpot

    2015-05-01

    Full Text Available This article analyses perceptions of residents of the Seychelles in the western Indian Ocean in relation to a long-running debate over small island developing states (SIDS as to whether they are vulnerable or resilient. The results of data obtained from 25 key informant interviews and 70 household surveys conducted in 2013 showed that respondents perceived their country to be both vulnerable and resilient. Moreover, the data revealed that the relationship between vulnerability and resilience was complex, and that five interpretations of that relationship were evident: conflict, compromise, complementarity, symbiosis and transformation. Also, the conceptual distance between the two terms – vulnerability and resilience – was shown to be closer than may be commonly assumed. Finally, the paper questions whether the debate over vulnerability versus resilience is rightly confined to SIDS or could be equally applied to other states.

  17. Heel effect adaptive flat field correction of digital x-ray detectors

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Yongjian [X-ray Products, Varian Medical Systems Inc., Liverpool, New York 13088 (United States); Wang, Jue [Department of Mathematics, Union College, Schenectady, New York 12308 (United States)

    2013-08-15

    Purpose: Anode heel effect renders large-scale background nonuniformities in digital radiographs. Conventional offset/gain calibration is performed at mono source-to-image distance (SID), and disregards the SID-dependent characteristic of heel effect. It results in a residual nonuniform background in the corrected radiographs when the SID settings for calibration and correction differ. In this work, the authors develop a robust and efficient computational method for digital x-ray detector gain correction adapted to SID-variant heel effect, without resorting to physical filters, phantoms, complicated heel effect models, or multiple-SID calibration and interpolation.Methods: The authors present the Duo-SID projection correction method. In our approach, conventional offset/gain calibrations are performed only twice, at the minimum and maximum SIDs of the system in typical clinical use. A fast iterative separation algorithm is devised to extract the detector gain and basis heel patterns from the min/max SID calibrations. The resultant detector gain is independent of SID, while the basis heel patterns are parameterized by the min- and max-SID. The heel pattern at any SID is obtained from the min-SID basis heel pattern via projection imaging principles. The system gain desired at a specific acquisition SID is then constructed using the projected heel pattern and detector gain map.Results: The method was evaluated for flat field and anatomical phantom image corrections. It demonstrated promising improvements over interpolation and conventional gain calibration/correction methods, lowering their correction errors by approximately 70% and 80%, respectively. The separation algorithm was able to extract the detector gain and heel patterns with less than 2% error, and the Duo-SID corrected images showed perceptually appealing uniform background across the detector.Conclusions: The Duo-SID correction method has substantially improved on conventional offset/gain corrections for

  18. Heel effect adaptive flat field correction of digital x-ray detectors

    International Nuclear Information System (INIS)

    Yu, Yongjian; Wang, Jue

    2013-01-01

    Purpose: Anode heel effect renders large-scale background nonuniformities in digital radiographs. Conventional offset/gain calibration is performed at mono source-to-image distance (SID), and disregards the SID-dependent characteristic of heel effect. It results in a residual nonuniform background in the corrected radiographs when the SID settings for calibration and correction differ. In this work, the authors develop a robust and efficient computational method for digital x-ray detector gain correction adapted to SID-variant heel effect, without resorting to physical filters, phantoms, complicated heel effect models, or multiple-SID calibration and interpolation.Methods: The authors present the Duo-SID projection correction method. In our approach, conventional offset/gain calibrations are performed only twice, at the minimum and maximum SIDs of the system in typical clinical use. A fast iterative separation algorithm is devised to extract the detector gain and basis heel patterns from the min/max SID calibrations. The resultant detector gain is independent of SID, while the basis heel patterns are parameterized by the min- and max-SID. The heel pattern at any SID is obtained from the min-SID basis heel pattern via projection imaging principles. The system gain desired at a specific acquisition SID is then constructed using the projected heel pattern and detector gain map.Results: The method was evaluated for flat field and anatomical phantom image corrections. It demonstrated promising improvements over interpolation and conventional gain calibration/correction methods, lowering their correction errors by approximately 70% and 80%, respectively. The separation algorithm was able to extract the detector gain and heel patterns with less than 2% error, and the Duo-SID corrected images showed perceptually appealing uniform background across the detector.Conclusions: The Duo-SID correction method has substantially improved on conventional offset/gain corrections for

  19. Postnatal parental smoking: An important risk factor for SIDS

    NARCIS (Netherlands)

    G. Liebrechts-Akkerman (Germaine); O. Lao Grueso (Oscar); F. Liu (Fan); B.E. van Sleuwen (Bregje); A.C. Engelberts (Adele); M.P. l' Hoir (Monique); H.W. Tiemeier (Henning); M.H. Kayser (Manfred)

    2011-01-01

    textabstractBackground: Sudden infant death syndrome (SIDS) is the unexpected death of an infant that remains unexplained after a thorough investigation of the circumstances, family history, paediatric investigation and complete autopsy. In Western society, it is the leading cause of post-neonatal

  20. [Trauma surgery in Pacific Small Island Developing States (SIDS)].

    Science.gov (United States)

    Oberli, H; Martin, C

    2017-10-01

    The small developing countries in the Pacific are grouped together as Small Island Development States (SIDS) because they face similar problems which they cannot cope with nationally. They are developing countries, so-called low and lower middle income countries (LMIC), are economically weak and the islands of the different nations are widely scattered. Approximately 80% of the 10 million inhabitants live in rural regions. Over 40% of patients in the surgical departments of hospitals are hospitalized for injuries, and this tendency is increasing. Fractures of the upper extremities are relatively more frequent in the Pacific than in the countries of the North. Long distances, lack of possibilities for treatment and lack of transport often cause complications, such as infected open fractures, pseudarthrosis and posttraumatic malformations. There are too few hospitals with sufficiently competent surgeons, anesthetists and obstetricians (SAO) and appropriate equipment. The PIOA was founded in Honiara, Solomon Islands, and offers surgeons of the Pacific SIDS a comprehensive, structured trauma and orthopedic surgery training in their own countries. It lasts 4 years and leads to an M‑Med (orthopaedic surgery) diploma and to a Fellowship of the International College of Surgeons (FICS), which are both recognized by the participating hospitals. It is free for participants. The AOAF is an independent organization with the only aim to enhance trauma surgery capacity in LMICs. The AOAF supports the PIOA program together with the Wyss Medical Foundation. Currently, 18 trainees from 8 Pacific SIDS are participating in the PIOA training program.

  1. Sudden infant death syndrome (SIDS)--standardised investigations and classification

    DEFF Research Database (Denmark)

    Bajanowski, Thomas; Vege, Ashild; Byard, Roger W

    2007-01-01

    Sudden infant death syndrome (SIDS) still accounts for considerable numbers of unexpected infant deaths in many countries. While numerous theories have been advanced to explain these events, it is increasingly clear that this group of infant deaths results from the complex interaction of a variet...

  2. Postnatal parental smoking: An important risk factor for SIDS

    NARCIS (Netherlands)

    Liebrechts-Akkerman, G.; Lao, O.; Liu, F.; Sleuwen, B.E. van; Engelberts, A.C.; L'Hoir, M.P.; Tiemeier, H.W.; Kayser, M.

    2011-01-01

    Background: Sudden infant death syndrome (SIDS) is the unexpected death of an infant that remains unexplained after a thorough investigation of the circumstances, family history, paediatric investigation and complete autopsy. In Western society, it is the leading cause of post-neonatal death below 1

  3. CapaSIDS : Capacity Building and Knowledge on Sustainable ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    CapaSIDS : Capacity Building and Knowledge on Sustainable Responses to Climate Change in Small Island States. Tourism is the main economic sector in ... Gouvernance axée sur la collaboration : gestion des risques associés aux inondations et à l'élévation du niveau de la mer au Cap. La ville du Cap doit relever un ...

  4. Variations of radiation intensity as a function of position in radiation field of a mammographic unit of 760 mm SID with Mo anode and 20 μm Mo added filter

    International Nuclear Information System (INIS)

    Noriah Jamal

    2001-01-01

    There are many effects that contribute to radiation field nonuniformity in mammography, including the heel effect and shorter source to image distance (SID), inverse square law and different photon path lengths through various attenuating media (the x-ray tube beryllium window, the added filter, the mirror, and the compression paddle) throughout the field. Variations of radiation intensity was investigated as a function of position in the radiation field (with compression paddle in place)of a mammographic unit in 760 mm SID with Mo anode and 20 μm Mo added filter. Reduction in radiation intensity along central axis of up to 19.40%, 19.13% and 19.34% were noted at 24, 26 and 28 kVp respectively. Radiation intensity also drops off to the left and right of the central axis. As a function of position in the field, we also found that the variations of optical density correlate well with the measured radiation intensity changes. (Author)

  5. Safe Sleep for Your Baby: Reduce the Risk of SIDS and Other Sleep-Related Causes of Infant Death

    Science.gov (United States)

    ... Fast facts about SIDS: SIDS is the leading cause of death in babies 1 month to 1 year of ... baby to die suddenly and unexpectedly. Sleep-related causes of infant death are those linked to how or where a ...

  6. SIDS and other sleep-related infant deaths: expansion of recommendations for a safe infant sleeping environment.

    Science.gov (United States)

    Moon, Rachel Y

    2011-11-01

    Despite a major decrease in the incidence of sudden infant death syndrome (SIDS) since the American Academy of Pediatrics (AAP) released its recommendation in 1992 that infants be placed for sleep in a nonprone position, this decline has plateaued in recent years. Concurrently, other causes of sudden unexpected infant death occurring during sleep (sleep-related deaths), including suffocation, asphyxia, and entrapment, and ill-defined or unspecified causes of death have increased in incidence, particularly since the AAP published its last statement on SIDS in 2005. It has become increasingly important to address these other causes of sleep-related infant death. Many of the modifiable and nonmodifiable risk factors for SIDS and suffocation are strikingly similar. The AAP, therefore, is expanding its recommendations from being only SIDS-focused to focusing on a safe sleep environment that can reduce the risk of all sleep-related infant deaths including SIDS. The recommendations described in this report include supine positioning, use of a firm sleep surface, breastfeeding, room-sharing without bed-sharing, routine immunization, consideration of a pacifier, and avoidance of soft bedding, overheating, and exposure to tobacco smoke, alcohol, and illicit drugs. The rationale for these recommendations is discussed in detail in this technical report. The recommendations are published in the accompanying "Policy Statement--Sudden Infant Death Syndrome and Other Sleep-Related Infant Deaths: Expansion of Recommendations for a Safe Infant Sleeping Environment," which is included in this issue (www.pediatrics.org/cgi/doi/10.1542/peds.2011-2220).

  7. Allocating the economic benefits of renewable energy between stakeholders on Small Island Developing States (SIDS): Arguments for a balanced approach

    International Nuclear Information System (INIS)

    Spiegel-Feld, Danielle; Rudyk, Bryce; Philippidis, George

    2016-01-01

    For many Small Island Developing States (SIDS) the cost of producing electricity from imported fossil fuels is so high and the cost of renewable energy technology has fallen so significantly that transitioning towards renewable energy is likely to produce cost savings. A recent workshop at NYU School of Law, which brought together SIDS utility representatives with a leading renewable energy developer and other stakeholders, provided strong support for this prediction. Utilities are likely to own the majority of renewable energy assets in SIDS and will therefore be the initial custodians of any cost savings renewable energy provides. This raises a key policy question: to what extent should SIDS utilities pass on these savings to consumers by lowering electricity rates? We analyze this overlooked element of energy policy and highlight undesirable consequences that complete disbursement of the savings to consumers could cause. - Highlights: • Renewables will create savings in SIDS by lowering electricity production costs. • Utilities are likely to own the bulk of renewable energy assets in SIDS. • Policymakers will need to decide how to divide savings among stakeholders. • There are compelling reasons to allow utilities to retain part of the savings. • Creditors can play a role in ensuring a prudent distribution of savings.

  8. GIS embedded hydrological modeling: the SID&GRID project

    Science.gov (United States)

    Borsi, I.; Rossetto, R.; Schifani, C.

    2012-04-01

    The SID&GRID research project, started April 2010 and funded by Regione Toscana (Italy) under the POR FSE 2007-2013, aims to develop a Decision Support System (DSS) for water resource management and planning based on open source and public domain solutions. In order to quantitatively assess water availability in space and time and to support the planning decision processes, the SID&GRID solution consists of hydrological models (coupling 3D existing and newly developed surface- and ground-water and unsaturated zone modeling codes) embedded in a GIS interface, applications and library, where all the input and output data are managed by means of DataBase Management System (DBMS). A graphical user interface (GUI) to manage, analyze and run the SID&GRID hydrological models based on open source gvSIG GIS framework (Asociación gvSIG, 2011) and a Spatial Data Infrastructure to share and interoperate with distributed geographical data is being developed. Such a GUI is thought as a "master control panel" able to guide the user from pre-processing spatial and temporal data, running the hydrological models, and analyzing the outputs. To achieve the above-mentioned goals, the following codes have been selected and are being integrated: 1. Postgresql/PostGIS (PostGIS, 2011) for the Geo Data base Management System; 2. gvSIG with Sextante (Olaya, 2011) geo-algorithm library capabilities and Grass tools (GRASS Development Team, 2011) for the desktop GIS; 3. Geoserver and Geonetwork to share and discover spatial data on the web according to Open Geospatial Consortium; 4. new tools based on the Sextante GeoAlgorithm framework; 5. MODFLOW-2005 (Harbaugh, 2005) groundwater modeling code; 6. MODFLOW-LGR (Mehl and Hill 2005) for local grid refinement; 7. VSF (Thoms et al., 2006) for the variable saturated flow component; 8. new developed routines for overland flow; 9. new algorithms in Jython integrated in gvSIG to compute the net rainfall rate reaching the soil surface, as input for

  9. A qualitative study in parental perceptions and understanding of SIDS-reduction guidance in a UK bi-cultural urban community.

    Science.gov (United States)

    Crane, Denise; Ball, Helen L

    2016-01-30

    Differences in both Sudden Infant Death Syndrome (SIDS) rates and infant care practices between white British and South Asians in UK are well known, but research has not yet examined how these two groups understand and implement SIDS-reduction guidance. This study aimed to discover how white British and Pakistani mothers in Bradford recall, understand and interpret SIDS-reduction guidance, and to explore whether and how they implement this guidance in caring for their infants. In-depth narrative interviews with 46 mothers (25 white British origin and 21 Pakistani origin) of 8-12 week old infants recruited from the pool of participants enrolled in the 'Born in Bradford' (BiB) cohort study. All mothers were aware of UK SIDS-reduction guidance from leaflets presented to them during antenatal or postnatal interactions with health care providers. Pakistani mothers tended to dismiss the guidance in toto as being irrelevant to their cultural practices; white British mothers dismissed, adapted and adopted aspects of the guidance to suit their preferred parenting decisions and personal circumstances. Many mothers misunderstood or misinterpreted the guidance given and explained their infant care behaviour according to their social and cultural circumstances. Current SIDS reduction information in the UK does not meet the needs of immigrant families, and is easily misinterpreted or misunderstood by mothers from all sections of the community. Tailored information acknowledging cultural differences in infant care practices is vital, as is greater discussion with all mothers about the reasons for SIDS reduction guidance.

  10. "Sina küsid minult : Miks sa rikud..." : [luuletused] / Jaan Kross

    Index Scriptorium Estoniae

    Kross, Jaan, 1920-2007

    2007-01-01

    Sisu: "Sina küsid minult: Miks sa rikud..." ; Pigilinnu ballaad ; Lind ; "Väikemees hüüdis mind..." ; Huntide algkooli zoloogiatunnis ; Varesed ; "Nii väike loom kui siil..." ; Imeline aas ; Tiivad ; Veekell ; Armastuselaul ; Lähedus

  11. Maqâsid al-Qur’ân dan Deradikalisasi Penafsiran dalam Konteks Keindonesiaan

    Directory of Open Access Journals (Sweden)

    Ulya Fikriyati

    2015-09-01

    Full Text Available This article deals with the viewpoint that the reading of the Qur’ân by a certain generation is subject to criticism by the following generation. The article seeks to offer, as an example, the deradicalization of interpreting the so-called ‘radical’ verses of the Qur’ân in Indonesian context. Islam in Indonesia always interact with various races, ethnicities, religions and beliefs, and therefore requires a type of exegesis different from other regions such as the Middle East. For the radicalization of interpretation, this article offers what is called the maqâsid al-Qur’ân as its parameter. The maqâsid al-Qur’ân consists of seven points: 1 Hifz al-dîn wa tatwîr wasâilih, 2 Hifz al-nafs wa tatwîruhâ, 3 Hifz al-‘aql wa tatwîruh, 4 Hifz al-mâl wa tanmîyat wasâilih, 5 Hifz al-‘ird wa tatwîr al-wasâil li al-husûl ‘alayh, 6 Tahqîq al-huqûq al-insânîyah wa mâ yandarij tahtahâ, 7 Hifz al-‘âlam wa ‘imâratuhâ. As spirit and parameter, the maqâsid al-Qur’ân necessitates the dialectics of dynamic interpretation without any judgment of infidelity or heresy. If a certain reading of the Qur’anic verses deviates from these seven maqâsid al-Qur’ân above, it deserves to be examined further, but not to be immediately suppressed.

  12. Driving the SID chip: Assembly language, composition, and sound design for the C64

    Directory of Open Access Journals (Sweden)

    James Newman

    2017-12-01

    Full Text Available The MOS6581, more commonly known as the Sound Interface Device, or SID chip, was the sonic heart of the Commodore 64 home computer. By considering the chip’s development, specification, uses and creative abuses by composers and programmers, alongside its continuing legacy, this paper argues that, more than any other device, the SID chip is responsible for shaping the sound of videogame music. Compared with the brutal atonality of chips such as Atari’s TIA, the SID chip offers a complex 3-channel synthesizer with dynamic waveform selection, per-channel ADSR envelopes, multi-mode filter, ring and cross modulation. However, while the specification is sophisticated, the exploitation of the vagaries and imperfections of the chip are just as significant to its sonic character. As such, the compositional, sound design and programming techniques developed by 1980s composer-coders like Rob Hubbard and Martin Galway are central in defining the distinctive sound of C64 gameplay. Exploring the affordances of the chip and the distinctive ways they were harnessed, the argument of this paper centers on the inexorable link between the technological and the musical. Crucially, composers like Hubbard et al. developed their own bespoke low-level drivers to interface with the SID chip to create pseudo-polyphony through rapid arpeggiation and channel sharing, drum synthesis through waveform manipulation, portamento, and even sample playback. This paper analyses the indivisibility of sound design, synthesis and composition in the birth of these musical forms and aesthetics, and assesses their impact on what would go on to be defined as chiptunes.

  13. A re-audit of the use of definitions of sudden infant death syndrome (SIDS) in peer-reviewed literature.

    Science.gov (United States)

    Byard, Roger W; Lee, Vivian

    2012-11-01

    The use of different definitions of sudden infant death syndrome (SIDS) may make comparison of data among studies difficult. Fifty randomly selected papers dealing with SIDS that were published between 2010 and 2011 in peer-reviewed journals were reviewed to determine whether one of three internationally accepted definitions of SIDS had been either written in the text or referenced. A significant improvement in the use of definitions has occurred since 2005, with the percentage of papers either quoting or referencing a standard definition increasing by 26%, from 42 to 68%. The 1989 NICHD definition remained the most commonly used definition (35.1%) followed by the 2004 San Diego definition (26.3%). Although the percentage of papers where either no definition was provided or where an idiosyncratic or mis-cited definition was used fell 26%, from 58 to 32%, nearly one in three papers published on SIDS in peer-reviewed journals that were included in this study still did not cite a standard definition. Copyright © 2012 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  14. Back to Sleep: Reduce the Risk of Sudden Infant Death Syndrome (SIDS) [and] Questions and Answers for Professionals on Infant Sleeping Position and SIDS.

    Science.gov (United States)

    Health Resources and Services Administration (DHHS/PHS), Washington, DC. Maternal and Child Health Bureau.

    The "Back to Sleep" public health campaign, which recommends that infants be placed on their backs for sleeping help reduce the risk of Sudden Infant Death Syndrome (SIDS), was initiated in 1994. The campaign was led by the National Institute of Child Health and Human Development, and co-sponsored by the U.S. Public Health Service, the…

  15. Particle Identification algorithm for the CLIC ILD and CLIC SiD detectors

    CERN Document Server

    Nardulli, J

    2011-01-01

    This note describes the algorithm presently used to determine the particle identification performance for single particles for the CLIC ILD and CLIC SiD detector concepts as prepared in the CLIC Conceptual Design Report.

  16. Mutations in Genes Encoding Cardiac Ion Channels Previously Associated With Sudden Infant Death Syndrome (SIDS) Are Present With High Frequency in New Exome Data

    DEFF Research Database (Denmark)

    Andreasen, Charlotte Hartig; Refsgaard, Lena; Nielsen, Jonas B

    2013-01-01

    National Heart, Lung, and Blood Institute Grand Opportunity (NHLBI GO) Exome Sequencing Project (ESP) provided important knowledge on genetic variation in the background population. Our aim was to identify all variants previously associated with SIDS in ESP to improve the discrimination between plausible......Sudden infant death syndrome (SIDS) is the leading cause of death in the first 6 months after birth in the industrialized world. The genetic contribution to SIDS has been investigated intensively and to date, 14 cardiac channelopathy genes have been associated with SIDS. Newly published data from...

  17. Arg279 is the key regulator of coenzyme selectivity in the flavin-dependent ornithine monooxygenase SidA.

    Science.gov (United States)

    Robinson, Reeder; Franceschini, Stefano; Fedkenheuer, Michael; Rodriguez, Pedro J; Ellerbrock, Jacob; Romero, Elvira; Echandi, Maria Paulina; Martin Del Campo, Julia S; Sobrado, Pablo

    2014-04-01

    Siderophore A (SidA) is a flavin-dependent monooxygenase that catalyzes the NAD(P)H- and oxygen-dependent hydroxylation of ornithine in the biosynthesis of siderophores in Aspergillus fumigatus and is essential for virulence. SidA can utilize both NADPH or NADH for activity; however, the enzyme is selective for NADPH. Structural analysis shows that R279 interacts with the 2'-phosphate of NADPH. To probe the role of electrostatic interactions in coenzyme selectivity, R279 was mutated to both an alanine and a glutamate. The mutant proteins were active but highly uncoupled, oxidizing NADPH and producing hydrogen peroxide instead of hydroxylated ornithine. For wtSidA, the catalytic efficiency was 6-fold higher with NADPH as compared to NADH. For the R279A mutant the catalytic efficiency was the same with both coenyzmes, while for the R279E mutant the catalytic efficiency was 5-fold higher with NADH. The effects are mainly due to an increase in the KD values, as no major changes on the kcat or flavin reduction values were observed. Thus, the absence of a positive charge leads to no coenzyme selectivity while introduction of a negative charge leads to preference for NADH. Flavin fluorescence studies suggest altered interaction between the flavin and NADP⁺ in the mutant enzymes. The effects are caused by different binding modes of the coenzyme upon removal of the positive charge at position 279, as no major conformational changes were observed in the structure for R279A. The results indicate that the positive charge at position 279 is critical for tight binding of NADPH and efficient hydroxylation. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Siff ja Kanajev müüsid Muuga rahamasina / Peeter Raidla, Mariliis Pinn

    Index Scriptorium Estoniae

    Raidla, Peeter, 1955-

    2007-01-01

    Endel Siff ja Anatoli Kanajev müüsid osaluse Pakterminalis ligi miljardi krooni eest Hollandi suurkontsernile Royal Vopak. Diagramm: Royal Vopaki aktsia hind. Vt. samas: E.O.S. tahab ühineda Pakterminaliga

  19. Optimal foetal growth in the reduction of learning and behaviour disorder and prevention of sudden infant death (SIDS) after the first month.

    Science.gov (United States)

    Saugstad, L F

    1997-09-01

    A theory is presented that a diet low in polyunsaturated fatty acids (PUFA) in the third trimester of pregnancy may delay myelination and brain maturation. This may underpin learning and behaviour disorders and sudden infant death (SIDS) after the first month, conditions that are associated with lower than average birthweight. Epidemiological evidence is reviewed showing an inverse relation between the proportion of heavy newborns (> 3500 g) and infant mortality rate. Some countries with a lower proportion of heavy newborns despite equally high standards of living and medical care have higher post-neonatal death rates. The higher rates are solely due to SIDS which has a peak mortality within 80-100 days. It is hypothesised that as this is a time when myelination peaks, SIDS may be due to maturational delay. Evidence of subtle CNS changes in brainstem structures and in the neuromuscular system supports an instability in brainstem control systems. Moderate iatrogenic dietary restriction predominates today, but a rising number of women favour a low-caloric low-fat diet especially in the third trimester when the foetus is most susceptible. This may lead to a depressed birthweight, delayed somatic growth and neuronal maturation, such as is observed in SIDS victims. The majority exposed to suboptimal conditions survive, but a few suffer SIDS; confirming post-neonatal susceptibility. Many, especially males, present minor CNS signs and learning/behaviour disorders that could be the sequelae of repeated hypoxic episodes, such as recorded in more than 80% of SIDS victims. To reduce learning/behaviour disorders and prevent death from SIDS after the first month, it is necessary to ensure optimal development by promoting foetal growth. It is advised to avoid unnecessary dieting and to favour a diet high in PUFAs, thus prolonging pregnancy and so increasing birthweight.

  20. Differential role of gpaB and sidA gene expressions in relation to virulence in Aspergillus species from patients with invasive aspergillosis.

    Science.gov (United States)

    Ghods, Nayereh; Falahati, Mehraban; Roudbary, Maryam; Farahyar, Shirin; Shamaei, Masoud; Pourabdollah, Mahin; Seif, Farhad

    2018-02-03

    The virulence genes in invasive aspergillosis (IA) have not been analyzed adequately. The present study was designed to evaluate the expression of gpaB and sidA genes, which are important virulence genes in Aspergillus spp. from bronchoalveolar lavage (BAL) samples. Direct examination and culture on Czapek Agar and Sabouraud Dextrose Agar media were performed for 600 BAL specimens isolated from patients with possible aspergillosis. A Galactomannan ELISA assay was also carried out. The expression levels of the gpaB and sidA genes in isolates were analyzed using quantitative real-time PCR (qRT-PCR). We identified 2 species, including Aspergillus flavus (A. flavus) and Aspergillus fumigatus (A. fumigatus) in 25 positive samples for invasive aspergillosis as validated using GM-ELISA. A. flavus is the main pathogen threatening transplant recipients and cancer patients worldwide. In this study, A. flavus had low levels of the gpaB gene expression compared to A. fumigatus (p=0.006). The highest sidA expression was detected in transplant recipients (p=0.05). There was no significant correlation between sidA expression and underlying disease (p=0.15). The sidA and gpaB gene expression patterns may provide evidence that these virulence genes play important roles in the pathogenicity of Aspergillus isolates; however, there are several regulatory genes responsible for the unexpressed sidA and gpaB genes in the isolates. Copyright © 2018 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. All rights reserved.

  1. The Aspergillus fumigatus siderophore biosynthetic gene sidA, encoding L-ornithine N5-oxygenase, is required for virulence.

    Science.gov (United States)

    Hissen, Anna H T; Wan, Adrian N C; Warwas, Mark L; Pinto, Linda J; Moore, Margo M

    2005-09-01

    Aspergillus fumigatus is the leading cause of invasive mold infection and is a serious problem in immunocompromised populations worldwide. We have previously shown that survival of A. fumigatus in serum may be related to secretion of siderophores. In this study, we identified and characterized the sidA gene of A. fumigatus, which encodes l-ornithine N(5)-oxygenase, the first committed step in hydroxamate siderophore biosynthesis. A. fumigatus sidA codes for a protein of 501 amino acids with significant homology to other fungal l-ornithine N(5)-oxygenases. A stable DeltasidA strain was created by deletion of A. fumigatus sidA. This strain was unable to synthesize the siderophores N',N",N'''-triacetylfusarinine C (TAF) and ferricrocin. Growth of the DeltasidA strain was the same as that of the wild type in rich media; however, the DeltasidA strain was unable to grow in low-iron defined media or media containing 10% human serum unless supplemented with TAF or ferricrocin. No significant differences in ferric reduction activities were observed between the parental strain and the DeltasidA strain, indicating that blocking siderophore secretion did not result in upregulation of this pathway. Unlike the parental strain, the DeltasidA strain was unable to remove iron from human transferrin. A rescued strain (DeltasidA + sidA) was constructed; it produced siderophores and had the same growth as the wild type on iron-limited media. Unlike the wild-type and rescued strains, the DeltasidA strain was avirulent in a mouse model of invasive aspergillosis, indicating that sidA is necessary for A. fumigatus virulence.

  2. A study of changes in the primary dose penetrating the protective apron on SID in x-ray radiography

    International Nuclear Information System (INIS)

    Choi, Seong Kwan

    2016-01-01

    This study is to figure out the amount of primary X-ray generated in SID 50cm, 1m, and 2m penetrating protective aprons in X-ray radiography for hands, skull, and lumbar spine. Results are as follows: Firstly, the exposure dose of primary X-ray which is low such as that of hand X-ray may be reduced by 270 times if protective aprons are worn, but it still slightly penetrates 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Secondly, the exposure dose of primary X-ray which is moderate such as that of skull X-ray may be reduced by 22 times if protective aprons are worn, but it still fairly penetrates 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Thirdly, the exposure dose of primary X-ray which is very high such as that of lumbar spine X-ray may be reduced b y 13 times if protective aprons a re worn, but it still penetrates a lot 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Therefore, people in X-ray room should not only wear protective aprons at any spaces that the primary X-ray can reach, but also need to stand behind the thick Pb shield to protect the body if it is inevitable to stay in the room

  3. A study of changes in the primary dose penetrating the protective apron on SID in x-ray radiography

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Seong Kwan [Dept. of Radiological Technology, Kwangju Health University, Gwangju (Korea, Republic of)

    2016-12-15

    This study is to figure out the amount of primary X-ray generated in SID 50cm, 1m, and 2m penetrating protective aprons in X-ray radiography for hands, skull, and lumbar spine. Results are as follows: Firstly, the exposure dose of primary X-ray which is low such as that of hand X-ray may be reduced by 270 times if protective aprons are worn, but it still slightly penetrates 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Secondly, the exposure dose of primary X-ray which is moderate such as that of skull X-ray may be reduced by 22 times if protective aprons are worn, but it still fairly penetrates 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Thirdly, the exposure dose of primary X-ray which is very high such as that of lumbar spine X-ray may be reduced b y 13 times if protective aprons a re worn, but it still penetrates a lot 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Therefore, people in X-ray room should not only wear protective aprons at any spaces that the primary X-ray can reach, but also need to stand behind the thick Pb shield to protect the body if it is inevitable to stay in the room.

  4. Particle mis-identification rate algorithm for the CLIC ILD and CLIC SiD detectors

    CERN Document Server

    Nardulli, J

    2011-01-01

    This note describes the algorithm presently used to determine the particle mis- identification rate and gives results for single particles for the CLIC ILD and CLIC SiD detector concepts as prepared for the CLIC Conceptual Design Report.

  5. Definition of Sudden Infant Death and Sudden Intrauterine Unexpected Death Syndromes (SIDS and SIUDS with Regard to the Anatomo-Pathological Examination

    Directory of Open Access Journals (Sweden)

    Giulia Ottaviani

    2016-09-01

    Full Text Available Crib death, or sudden infant death syndrome (SIDS, is the most frequent form of death in the first year of life, striking one baby in every 1,700–2,000. Yet despite advances in maternal-infant care, sudden intrauterine unexplained/unexpected death syndrome (SIUDS, has a six-eightfold greater incidence than that of SIDS. Frequent congenital abnormalities, likely morphological substrates for SIDS-SIUDS, were detected, mainly represented by alterations of the cardiac conduction system, such as accessory pathways and abnormal resorptive degeneration, and hypoplasia/agenesis of the vital brainstem structures. On the basis of these considerations, the new common definition of the SIDS-SIUDS complex is The sudden death of a fetus after the 25th gestational week or infant under one year of age which is unexpected by history and remains unexplained after a thorough case investigation, including examination of the death scene, performance of a general autopsy and examination of the fetal adnexa. Therefore, given that the general autopsy does not disclose any cause of death, a more in-depth histopathological analysis of the cardiac conduction system and autonomic nervous system by specialized pathologists will become necessary.

  6. Injury risk curves for the WorldSID 50th male dummy.

    Science.gov (United States)

    Petitjean, Audrey; Trosseille, Xavier; Petit, Philippe; Irwin, Annette; Hassan, Joe; Praxl, Norbert

    2009-11-01

    The development of the WorldSID 50th percentile male dummy was initiated in 1997 by the International Organisation for Standardisation (ISO/SC12/TC22/WG5) with the objective of developing a more biofidelic side impact dummy and supporting the adoption of a harmonised dummy into regulations. More than 45 organizations from all around the world have contributed to this effort including governmental agencies, research institutes, car manufacturers and dummy manufacturers. The first production version of the WorldSID 50th male dummy was released in March 2004 and demonstrated an improved biofidelity over existing side impact dummies. Full scale vehicle tests covering a wide range of side impact test procedures were performed worldwide with the WorldSID dummy. However, the vehicle safety performance could not be assessed due to lack of injury risk curves for this dummy. The development of these curves was initiated in 2004 within the framework of ISO/SC12/TC22/WG6 (Injury criteria). In 2008, the ACEA- Dummy Task Force (TFD) decided to contribute to this work and offered resources for a project manager to coordinate of the effort of a group of volunteer biomechanical experts from international institutions (ISO, EEVC, VRTC/NHTSA, JARI, Transport Canada), car manufacturers (ACEA, Ford, General Motors, Honda, Toyota, Chrysler) and universities (Wayne State University, Ohio State University, John Hopkins University, Medical College of Wisconsin) to develop harmonized injury risk curves. An in-depth literature review was conducted. All the available PMHS datasets were identified, the test configurations and the quality of the results were checked. Criteria were developed for inclusion or exclusion of PMHS tests in the development of the injury risk curves. Data were processed to account for differences in mass and age of the subjects. Finally, injury risk curves were developed using the following statistical techniques, the certainty method, the Mertz/Weber method, the

  7. Monges sob o manto de generais: aristocracia imperial galo-romana e monasticismo nas obras de Sidônio Apolinário

    Directory of Open Access Journals (Sweden)

    Matheus Coutinho Figuinha

    2015-12-01

    Full Text Available As cartas e os poemas do nobre Sidônio Apolinário tendem a ser ignorados pelos estudiosos do monasticismo tardo-antigo. O presente texto é uma tentativa de preencher esta lacuna historiográfica. Meu objetivo é analisar as notícias de Sidônio acerca dos monges e monastérios de sua época, focando na relação da aristocracia imperial galo-romana com o monasticismo. As obras de Sidônio sugerem que, até o início da década de 480, a aristocracia imperial galo-romana, de modo geral, pouco se envolveu com monges e assuntos monásticos. Mas, ao mesmo tempo, elas revelam o interesse que monges eruditos e taumaturgos podiam despertar em grandes aristocratas e o papel que estes podiam ter no governo e no cotidiano de determinados monastérios.

  8. Molecular cloning and characterization of a SID-1-like gene in Plutella xylostella.

    Science.gov (United States)

    Wang, Huidong; Gong, Liang; Qi, Jiangwei; Hu, Meiying; Zhong, Guohua; Gong, Liang

    2014-11-01

    RNA interference (RNAi) signal can spread from the point where the double-stranded RNA (dsRNA) was initially applied to other cells or tissues. SID-related genes in Caenorhabditis elegans help in the spreading of this signal. However, the mechanisms of systemic RNAi are still not unveiled in insects. In this study, we cloned a full-length cDNA of sid-1-like gene, Pxylsid-1, from Plutella xylostella that contains 1,047 bp opening reading frame encoding a putative protein of 348 amino acids. This transcript is very much similar to the sil-1 in Bombyx mori (68.8%). The higher expression levels of Pxylsid-1 were found at the adult and fourth-instar stages compared to the second-instar stage with 21.48- and 10.36-fold increase, respectively. Its expression levels in different tissues were confirmed with the highest expression in the hemolymph, which showed 21.09-fold increase than the midgut; however it was lower in other tissues. The result of RNAi by feeding bacterially expressed dsRNA targeting Pxylace-1, which showed that the mRNA level of Pxylace-1 decreased by 34.52 and 64.04% after 36- and 72-h treatment, respectively. However, the mRNA level of Pxylsid-1 was not significantly induced when the Pxylace-1 was downregulated. Furthermore, we found that downregulation of Pxylsid-1 did not affect the RNAi effect of Pxylace-1. Hence, the Pxylsid-1 may not be involved in absorption of dsRNA from the midgut fluid. A further study is needed to uncover the function of Pxylsid-1. © 2014 Wiley Periodicals, Inc.

  9. Particle Identification performance for leptons in jets for the CLIC ILD and CLIC SiD detectors

    CERN Document Server

    Nardulli, J

    2011-01-01

    This note describes the particle identification performance for particles in jets for the CLIC ILD and CLIC SiD detector concepts as prepared in the CLIC Conceptual Design Report. The results are presented with and without the presence of the γγ → hadrons background events.

  10. Factors influencing maternal decision-making for the infant sleep environment in families at higher risk of SIDS: a qualitative study.

    Science.gov (United States)

    Pease, Anna; Ingram, Jenny; Blair, Peter S; Fleming, Peter J

    2017-01-01

    Qualitative interviews with mothers of babies at higher risk of sudden infant death syndrome (SIDS) were carried out to understand their views and decision-making process on the infant sleep environment and safe sleep messages. Twenty semi-structured interviews were conducted between February and November 2014 in deprived areas of Bristol, UK. Mothers were asked about their decision-making for the infant sleep environment and safe sleep messages including infant sleep position, co-sleeping, smoking, dummy use, feeding and disrupted routines. The interviews were transcribed, coded and thematic analysis carried out. Participants were invited based on an algorithm developed in a previous SIDS case control study that identified an increased risk of SIDS from four demographic characteristics: young maternal age, smoking during pregnancy, three or more children, and a measure of deprivation. The presence of three, or more characteristics led to being invited to take part in the qualitative study. Factors influencing mothers' adherence to the safe sleep messages included previous experience and the credibility of the advice given. They described disrupted routines that led to risky scenarios with a belief that occasional risks were acceptable. Where circumstances made following the advice more difficult they found alternative strategies to reduce the risk, including the use of movement monitors, regular checking and a belief that lighter maternal sleep in the presence of a baby was protective. Safer sleep messages should be tailored to fit with the lived realities of mothers, especially those at higher risk. The traditional list of 'do's' and 'don'ts' was not well accepted by this group. Interventions that seek to influence this higher-risk group should acknowledge mothers' own protective instincts and consider their beliefs and understanding behind the safer sleep messages if they are to be effective and encourage this group to change.

  11. Side impact injury prediction with fe simulations of the new advanced world sid fe dummy models

    NARCIS (Netherlands)

    Liu, Y.; Zhu, F.; Wang, Z.; Ratingen, M.R. van

    2007-01-01

    Two new World SID (50th and 5th) FE models were developed for providing virtual tools of predicting occupant injuries during vehicle side collisions. The virtual dummy models have been verified with their physical counterparts in aspects of lab certification tests, bio-fidelity and sled tests. Many

  12. Development of Readout Interconnections for the Si-W Calorimeter of SiD

    Energy Technology Data Exchange (ETDEWEB)

    Woods, M.; Fields, R.G.; Holbrook, B.; Lander, R.L.; Moskaleva, A.; Neher, C.; Pasner, J.; Tripathi, M.; /UC, Davis; Brau, J.E.; Frey, R.E.; Strom, D.; /Oregon U.; Breidenbach, M.; Freytag, D.; Haller, G.; Herbst, R.; Nelson, T.; /SLAC; Schier, S.; Schumm, B.; /UC, Santa Cruz

    2012-09-14

    The SiD collaboration is developing a Si-W sampling electromagnetic calorimeter, with anticipated application for the International Linear Collider. Assembling the modules for such a detector will involve special bonding technologies for the interconnections, especially for attaching a silicon detector wafer to a flex cable readout bus. We review the interconnect technologies involved, including oxidation removal processes, pad surface preparation, solder ball selection and placement, and bond quality assurance. Our results show that solder ball bonding is a promising technique for the Si-W ECAL, and unresolved issues are being addressed.

  13. Comparison of calculated and experimentally determined SID of CP and AA in complex diets differing in AA contents for grower finisher pigs.

    Science.gov (United States)

    Büsing, K; Berk, A; Müller, S; Kieckhäven, S; Krüger, K; Zeyner, A

    2017-10-01

    In practice, the content of standardized ileal digestible AA in complex feeds for pigs is calculated on the basis of tabulated values for individual feedstuffs. It comes into question, however, whether this truly reflects an accurate content based upon the estimate made for the individual feedstuffs. The objective of this study was to compare standardized ileal digestibility (SID) of crude protein (CP) and selected AA in complex feeds for grower and finisher pigs either calculated or experimentally determined. Six diets with increasing AA levels were prepared for grower (BW from 30 to 70 kg) and finisher (BW from 70 to 120 kg) feed. Crystalline L-lys, DL-met and L-thr were added to both diets, L-trp and L-val only to the grower feed. SID of both CP and AA was calculated from feed tables and experimentally determined in six adult minipigs (MINILEWE) with ileorectal anastomosis. With increasing AA levels, experimentally determined SID of supplemented AA increased (p AA via tabulated values for individual feedstuffs, however, seems to be acceptable for practical use. Journal of Animal Physiology and Animal Nutrition © 2017 Blackwell Verlag GmbH.

  14. Fast Track Finding in the ILC's Silicon Detector, SiD01

    International Nuclear Information System (INIS)

    Baker, David E.

    2007-01-01

    A fast track finder is presented which, unlike its more efficient, more computationally costly O(n3) time counterparts, tracks particles in O(n) time (for n being the number of hits). Developed as a tool for processing data from the ILC's proposed SiD detector, development of this fast track finder began with that proposed by Pablo Yepes in 1996 and adjusted to accommodate the changes in geometry of the SiD detector. First, space within the detector is voxellated, with hits assigned to voxels according to their r, φ, and η coordinates. A hit on the outermost layer is selected, and a 'sample space' is built from the hits in the selected hit's surrounding voxels. The hit in the sample space with the smallest distance to the first is then selected, and the sample space recalculated for this hit. This process continues until the list of hits becomes large enough, at which point the helical circle in the x, y plane is conformally mapped to a line in the x', y' plane, and hits are chosen from the sample spaces of the previous fit by selecting the hits which fit a line to the previously selected points with the smallest χ 2 . Track finding terminates when the innermost layer has been reached or no hit in the sample space fits those previously selected to an acceptable χ 2 . Again, a hit on the outermost layer is selected and the process repeats until no assignable hits remain. The algorithm proved to be very efficient on artificial diagnostic events, such as one hundred muons scattered at momenta of 1 GeV/c to 10 GeV/c. Unfortunately, when tracking simulated events corresponding to actual physics, the track finder's efficiency decreased drastically (mostly due to signal noise), though future data cleaning programs could noticeably increase its efficiency on these events

  15. Role of Ser-257 in the sliding mechanism of NADP(H) in the reaction catalyzed by the Aspergillus fumigatus flavin-dependent ornithine N5-monooxygenase SidA.

    Science.gov (United States)

    Shirey, Carolyn; Badieyan, Somayesadat; Sobrado, Pablo

    2013-11-08

    SidA (siderophore A) is a flavin-dependent N-hydroxylating monooxygenase that is essential for virulence in Aspergillus fumigatus. SidA catalyzes the NADPH- and oxygen-dependent formation of N(5)-hydroxyornithine. In this reaction, NADPH reduces the flavin, and the resulting NADP(+) is the last product to be released. The presence of NADP(+) is essential for activity, as it is required for stabilization of the C4a-hydroperoxyflavin, which is the hydroxylating species. As part of our efforts to determine the molecular details of the role of NADP(H) in catalysis, we targeted Ser-257 for site-directed mutagenesis and performed extensive characterization of the S257A enzyme. Using a combination of steady-state and stopped-flow kinetic experiments, substrate analogs, and primary kinetic isotope effects, we show that the interaction between Ser-257 and NADP(H) is essential for stabilization of the C4a-hydroperoxyflavin. Molecular dynamics simulation results suggest that Ser-257 functions as a pivot point, allowing the nicotinamide of NADP(+) to slide into position for stabilization of the C4a-hydroperoxyflavin.

  16. Correlation of Solar X-ray Flux and SID Modified VLF Signal Strength

    Science.gov (United States)

    2015-03-26

    Motivation ...……………………………………………………………………1-1 Background …………………………………………………………………….1-1 Research Objectives ……………………………………………………………1-3 II...SOLAR X-RAY FLUX AND SID MODIFIED VLF SIGNAL STRENGTH I. Introduction 1.1 Motivation The ionosphere greatly influences long wave radio...accomplished by a research group from Cambridge in the late 1940s. The group recorded the 16 kHz signal of the transmitter in Rugby , England, with the call

  17. WorldSID - an international project for the harmonisation and improvement of side impact dummies

    Energy Technology Data Exchange (ETDEWEB)

    Page, M. [Centre Europeen d' Etudes de Securite et d' Analyse des Risques (France); Cesari, D. [Institut National de Recherche sur les Transports et leur Securite, Arcueil (France); Hautmann, E. [BMW Group, Muenchen (Germany); Scherer, R. [Ford-Werke AG, Koeln (Germany); Uchimura, Takahiko [Nissan Motor Co. Ltd., Tokyo (Japan); Kostyniuk, G.W. [DaimlerChrysler (United States); Asakawa, Kazuhito [JAMA (Japan); Bortenschlager, K. [Audi AG, Ingoldstadt (Germany)

    2001-07-01

    In order to substantiate the efficiency of side impact protection measures, various side impact dummies are legally required in various countries. Moreover, these side impact dummies do not meet the currently requested bio-fidelity requirements. The target of the WorldSID project is to develop a new 50 per cent side impact dummy with at least good to excellent biofidelity, which will be used all over the world in all side impact test procedures, and thus will considerably contribute to harmonisation. Contents of the lecture: (a) Intention, initialisation, organisation of the project. (b) Technical and bio-mechanical specifications, design. (c) Prototype - first impressions of test, handling.. (d) Further project plans, targets. (orig.)

  18. Climate Change and Caribbean Small Island States: The State of Play

    Directory of Open Access Journals (Sweden)

    Benjamin, Lisa

    2010-01-01

    Full Text Available Studies have indicated that climate change is likely to have dramatic negative effects for Caribbean small island developing states. This article considers the main economic effects that climate change is anticipated to have in these vulnerable states, charts the progress of international negotiations at the 2009 Copenhagen conference, and provides a brief analysis of the impact of the Copenhagen Accord on Caribbean Small Island Developing States (SIDS.Although climate change has traditionally been seen solely as an environmental issue, its economic effects on vulnerable developing nations, such as Caribbean SIDS, forces a re-definition of climate change to that of a more complex union of environmental and developmental issues for these states. By highlighting some of the anticipated economic effects of climate change for Caribbean SIDS, the author aims to provide a broader context for the issue of climate change for Caribbean SIDS.

  19. Factors influencing maternal decision-making for the infant sleep environment in families at higher risk of SIDS:a qualitative study

    OpenAIRE

    Pease, Anna; Ingram, Jenny; Blair, Pete; Fleming, Peter

    2017-01-01

    Objective: Qualitative interviews with mothers of babies at higher risk of sudden infant death syndrome (SIDS) were carried out to understand their views and decision-making process on the infant sleep environment and safe sleep messages.Design and setting: Twenty semi-structured interviews were conducted between February and November 2014 in deprived areas of Bristol, UK. Mothers were asked about their decision-making for the infant sleep environment and safe sleep messages including infant ...

  20. Spatial interactions database development for effective probabilistic risk assessment

    International Nuclear Information System (INIS)

    Liming, J. K.; Dunn, R. F.

    2008-01-01

    relational database technology is applied at STPEGS Units I and 2. The paper presents ideas for streamlining the SID development and SIA applications processes and making them more effective and efficient to continuously update and maintain over the plant life cycle. The paper also suggests areas where SID information can be applied to support plant processes outside the PRA. (authors)

  1. Effects of intravenous solutions on acid-base equilibrium: from crystalloids to colloids and blood components.

    Science.gov (United States)

    Langer, Thomas; Ferrari, Michele; Zazzeron, Luca; Gattinoni, Luciano; Caironi, Pietro

    2014-01-01

    Intravenous fluid administration is a medical intervention performed worldwide on a daily basis. Nevertheless, only a few physicians are aware of the characteristics of intravenous fluids and their possible effects on plasma acid-base equilibrium. According to Stewart's theory, pH is independently regulated by three variables: partial pressure of carbon dioxide, strong ion difference (SID), and total amount of weak acids (ATOT). When fluids are infused, plasma SID and ATOT tend toward the SID and ATOT of the administered fluid. Depending on their composition, fluids can therefore lower, increase, or leave pH unchanged. As a general rule, crystalloids having a SID greater than plasma bicarbonate concentration (HCO₃-) cause an increase in plasma pH (alkalosis), those having a SID lower than HCO₃- cause a decrease in plasma pH (acidosis), while crystalloids with a SID equal to HCO₃- leave pH unchanged, regardless of the extent of the dilution. Colloids and blood components are composed of a crystalloid solution as solvent, and the abovementioned rules partially hold true also for these fluids. The scenario is however complicated by the possible presence of weak anions (albumin, phosphates and gelatins) and their effect on plasma pH. The present manuscript summarises the characteristics of crystalloids, colloids, buffer solutions and blood components and reviews their effect on acid-base equilibrium. Understanding the composition of intravenous fluids, along with the application of simple physicochemical rules best described by Stewart's approach, are pivotal steps to fully elucidate and predict alterations of plasma acid-base equilibrium induced by fluid therapy.

  2. Spectra and structure of silicon containing compounds. XXXII. Raman and infrared spectra, conformational stability, vibrational assignment and ab initio calculations of n-propylsilane-d0 and Si-d3.

    Science.gov (United States)

    Durig, James R; Pan, Chunhua; Guirgis, Gamil A

    2003-03-15

    The infrared (3100-40 cm(-1)) and Raman (3100-20 cm(-1)) spectra of gaseous and solid n-propylsilane, CH(3)CH(2)CH(2)SiH(3) and the Si-d(3) isotopomer, CH(3)CH(2)CH(2)SiD(3), have been recorded. Additionally, the Raman spectra of the liquids have been recorded and qualitative depolarization values obtained. Both the anti and gauche conformers have been identified in the fluid phases but only the anti conformer remains in the solid. Variable temperature (-105 to -150 degrees C) studies of the infrared spectra of n-propylsilane dissolved in liquid krypton have been recorded and the enthalpy difference has been determined to be 220+/-22 cm(-1) (2.63+/-0.26 kJ mol(-1)) with the anti conformer the more stable form. A similar value of 234+/-23 cm(-1) (2.80+/-0.28 kJ mol(-1)) was obtained for deltaH for the Si-d(3) isotopomer. At ambient temperature it is estimated that there is 30+/-2% of the gauche conformer present. The potential function governing the conformation interchange has been estimated from the far infrared spectral data, the enthalpy difference, and the dihedral angle of the gauche conformer, which is compared to the one predicted from ab initio MP2/6-31G(d) calculations. The barriers to conformational interchange are: 942, 970 and 716 cm(-1) for the anti to gauche, gauche to gauche, and gauche to anti conformers, respectively. Relatively complete vibrational assignments are proposed for both the n-propylsilane-d(0) and Si-d(3) molecules based on the relative infrared and Raman spectral intensities, infrared band contours, depolarization ratios, and normal coordinate calculations. The geometrical parameters, harmonic force constants, vibrational frequencies, infrared intensities, Raman activities and depolarization ratios, and energy differences have been obtained for the anti and gauche conformers from ab initio MP2/6-31G(d) calculations. Structural parameters and energy differences have also been obtained utilizing the larger 6-311 + G(d,p) and 6-311 + G(2

  3. Spectra and structure of silicon containing compounds. XXXII. Raman and infrared spectra, conformational stability, vibrational assignment and ab initio calculations of n-propylsilane-d 0 and Si-d 3

    Science.gov (United States)

    Durig, James R.; Pan, Chunhua; Guirgis, Gamil A.

    2003-03-01

    The infrared (3100-40 cm -1) and Raman (3100-20 cm -1) spectra of gaseous and solid n-propylsilane, CH 3CH 2CH 2SiH 3 and the Si-d 3 isotopomer, CH 3CH 2CH 2SiD 3, have been recorded. Additionally, the Raman spectra of the liquids have been recorded and qualitative depolarization values obtained. Both the anti and gauche conformers have been identified in the fluid phases but only the anti conformer remains in the solid. Variable temperature (-105 to -150 °C) studies of the infrared spectra of n-propylsilane dissolved in liquid krypton have been recorded and the enthalpy difference has been determined to be 220±22 cm -1 (2.63±0.26 kJ mol -1) with the anti conformer the more stable form. A similar value of 234±23 cm -1 (2.80±0.28 kJ mol -1) was obtained for Δ H for the Si-d 3 isotopomer. At ambient temperature it is estimated that there is 30±2% of the gauche conformer present. The potential function governing the conformation interchange has been estimated from the far infrared spectral data, the enthalpy difference, and the dihedral angle of the gauche conformer, which is compared to the one predicted from ab initio MP2/6-31G(d) calculations. The barriers to conformational interchange are: 942, 970 and 716 cm -1 for the anti to gauche, gauche to gauche, and gauche to anti conformers, respectively. Relatively complete vibrational assignments are proposed for both the n-propylsilane-d 0 and Si-d 3 molecules based on the relative infrared and Raman spectral intensities, infrared band contours, depolarization ratios, and normal coordinate calculations. The geometrical parameters, harmonic force constants, vibrational frequencies, infrared intensities, Raman activities and depolarization ratios, and energy differences have been obtained for the anti and gauche conformers from ab initio MP2/6-31G(d) calculations. Structural parameters and energy differences have also been obtained utilizing the larger 6-311+G(d,p) and 6-311+G(2d,2p) basis sets. From the isolated

  4. Changing conclusions on secondhand smoke in a sudden infant death syndrome review funded by the tobacco industry.

    Science.gov (United States)

    Tong, Elisa K; England, Lucinda; Glantz, Stanton A

    2005-03-01

    citation patterns for the referenced SIDS reviews. PM executives feared that SHS and maternal and child health issues would create a powerful and emotional impetus for smoke-free areas in the home, public areas, and the workplace. In response to the 1992 US EPA report on SHS, the Science and Technology Department of PM's Switzerland subsidiary, Fabriques de Tabac Reunies, searched for "independent" consultants to publish articles addressing SHS. The first industry-funded article was a literature review focusing on smoking and SIDS, conducted by consultant Peter Lee and co-author Allison Thornton, which stated that the association between parental smoking and SIDS could have been attributable to the failure to control fully for confounders. That first review has only been cited once, in the subsequent industry-funded review. In 1997, PM commissioned a consultant, Frank Sullivan, to write a review, with coauthor Susan Barlow, of all possible risk factors for SIDS. The first draft concluded that prenatal and postnatal smoking exposures are both independent risk factors for SIDS. After receiving comments and meeting with PM scientific executives, Sullivan changed his original conclusions on smoking and SIDS. The final draft was changed to emphasize the effects of prenatal maternal smoking and to conclude that postnatal SHS effects were "less well established." Changes in the draft to support this new conclusion included descriptions of Peter Lee's industry-funded review, a 1999 negative but underpowered study of SIDS risk and urinary cotinine levels, and criticisms of the conclusions of the National Cancer Institute report that SHS was causally associated with SIDS. In April 2001, the Sullivan review was published in the United Kingdom journal Paediatric and Perinatal Epidemiology, with a disclosure statement that acknowledged financial support from PM but did not acknowledge contributions from PM executives in the preparation of the review. By 2004, the Sullivan SIDS review

  5. Effect of feeding three lysine to energy diets on growth, body composition and age at puberty in replacement gilts

    Science.gov (United States)

    This study evaluated the effect of diets differing in standard ileal digestible (SID) lysine on lysine intake, growth rate, body composition and age at puberty on maternal line gilts. Crossbred Large White×Landrace gilts (n =641) were fed corn-soybean diets differing in SID lysine concentration (%, ...

  6. 29Si(d,3He)28Al reaction at 29 MeV

    International Nuclear Information System (INIS)

    Vernotte, J.; Berrier-Ronsin, G.; Fortier, S.; Hourani, E.; Kalifa, J.; Khendriche, A.; Maison, J.M.; Rosier, L.H.; Rotbard, G.

    1994-01-01

    The 29 Si(d, 3 He) 28 Al reaction has been investigated at 29 MeV incident energy. Observations using a split-pole magnetic spectrograph have been made of 55 levels of 28 Al in the range of excitation energy between 0 and 6.7 MeV. Most of them have been identified with 28 Al levels which have been previously observed by other techniques. The spectroscopic factors have been obtained for 23 of these levels through distorted-wave Born approximation analyses of measured angular distributions. The levels at E x =3.105 and 3.762 MeV have been definitely assigned J π =1 + and 0 + , respectively. Four levels which are populated through the pickup of a l p =1 proton have been observed at E x =4.998, 5.406, 6.021, and 6.652 MeV. The excitation energies and spectroscopic factors for positive-parity states were compared with the results of a recent, complete sd-shell space, shell-model calculation. This comparison led to the identification of 21 shell-model levels with experimental levels. This comparison seems accurate enough to make very likely the J π =3 + assignment for the levels at E x =2.988 and 4.597 MeV which were previously assigned J π =(1,3) +

  7. Simulation studies of the n{sup +}n{sup -} Si sensors having p-spray/p-stop implant for the SiD experiment

    Energy Technology Data Exchange (ETDEWEB)

    Saxena, Pooja; Ranjan, Kirti [Centre for Detector and Related Software Technology, Department of Physics and Astrophysics, University of Delhi, Delhi 110007 (India); Bhardwaj, Ashutosh, E-mail: abhardwaj@physics.du.ac.in [Centre for Detector and Related Software Technology, Department of Physics and Astrophysics, University of Delhi, Delhi 110007 (India); Shivpuri, R.K.; Bhattacharya, Satyaki [Centre for Detector and Related Software Technology, Department of Physics and Astrophysics, University of Delhi, Delhi 110007 (India)

    2011-12-01

    Silicon Detector (SiD) is one of the proposed detectors for the future International Linear Collider (ILC). In the innermost vertex of the ILC, Si micro-strip sensors will be exposed to the neutron background of around 1-1.6 Multiplication-Sign 10{sup 10} 1 MeV equivalent neutrons cm{sup -2} year{sup -1}. The p{sup +}n{sup -}n{sup +} double-sided Si strip sensors are supposed to be used as position sensitive sensors for SiD. The shortening due to electron accumulation on the n{sup +}n{sup -} side of these sensors leads to uniform spreading of signal over all the n{sup +} strips and thus ensuring good isolation between the n{sup +} strips becomes one of the major issues in these sensors. One of the possible solutions is the use of floating p-type implants introduced between the n{sup +} strips (p-stops) and another alternative is the use of uniform layer of p-type implant on the entire n-side (p-spray). However, pre-breakdown micro-discharge is reported because of the high electric field at the edge of the p-stop/p-spray. An optimization of the implant dose profile of the p-stop and p-spray is required to achieve good electrical isolation while ensuring satisfactory breakdown performance of the Si sensors. Preliminary results of the simulation study performed on the n{sup +}n{sup -} Si sensors having p-stop and p-spray using device simulation program, ATLAS, are presented.

  8. Le sujet entre sidération et jouissance: l'issue sublimatoire. À propos de l'œuvre de Francisco Brennand

    OpenAIRE

    Donard, Véronique

    2014-01-01

    Cet article traite de l'univers inconscient des sculptures de l'artiste brésilien Francisco Brennand (1927) et des mécanismes archaïques qui sous-tendent leur création. Axée sur la thématique de l'origine, cette approche des œuvres de Brennand étudie les racines du désir sexuel et son rapport aux objets partiels, considérant la sidération du sujet face à la cruauté d'une sexualité archaïque et la jouissance de l'artiste comme défi à la mort et à l'énigme du néant. Elle s'intéresse alors au pr...

  9. Evaluation of dilatometric techniques for studies of sintering kinetics

    International Nuclear Information System (INIS)

    El-Sayed Ali, M.; Toft Soerensen, O.

    1985-04-01

    The kinetics of the initial sintering stage of CeO 2 is evaluated by three different techniques: constant heating rate dilatometry, constant shrinkage rate dilatometry and a new technique recently introduced by the authors called Stepwise Isothermal Dilatometry (SID). Comparative measurements with these techniques showed that too high activation energies were obtained with the two first techniques, both of which can be termed as nonisothermal, whereas activation energies comparable to those reported for cation diffusion in other fluorite oxides were obtained with the latter technique. Of the three techniques SID is thus considered to be the most accurate for studies of the sintering kinetics. In contrast to the two nonisothermal techniques SID has the further advantage that both the controlling mechanism and its activation energy can be determined in a single experiment. From the SID-measurement it was concluded that the initial sintering stage of CeO 2 is controlled by grain-boundary diffusion. (author)

  10. Development of fluctuation monitor type sodium ionization detector

    International Nuclear Information System (INIS)

    Yamamoto, Hajime; Sato, Yoshihiko; Ibe, Eishi; Suzuoki, Akira

    1986-01-01

    In order to improve the sensitivity and the reliability of the sodium leak detection system used in the fast breeder reactors, a new type SID (sodium ionization detector) has been developed, in which the monitored signal is only the fluctuating component of the current between the filament and the ion collector. The fluctuating component was extracted by a band pass filter and its root mean square value was calculated as the SID signal. Fluctuation characteristics of the output current were studied by its frequency spectrum. The results revealed that the current spectrum was affected by the particle size distribution of the aerosol and was most clearly distinguished from that of the background current in the frequency region of 0.5 ∼ 10 Hz. Output characteristics of the fluctuation monitor type SID (FM-SID) were obtained as a function of sodium concentration in the gas. The FM-SID sensitivity was lowered by impurities in the gas, such as oxygen and water vapor. Finally, in comparisons with the conventional DC-SIDs, the background noise level of the FM-SID was much lower and S/N ratio was greatly improved. The detectable sodium concentration level was ten times lower than that of the DC-SID. (author)

  11. Effects of dietary valine:lysine ratio on the performance, amino acid composition of tissues and mRNA expression of genes involved in branched-chain amino acid metabolism of weaned piglets

    Directory of Open Access Journals (Sweden)

    Ye Tong Xu

    2018-01-01

    Full Text Available Objective The goal of this study was to investigate the effects of dietary standard ileal digestible (SID valine:lysine ratios on performance, intestinal morphology, amino acids of liver and muscle, plasma indices and mRNA expression of branched-chain amino acid (BCAA metabolism enzymes. Methods A total of 144 crossbred pigs (Duroc×Landrace×Large White weaned at 28±4 days of age (8.79±0.02 kg body weight were randomly allotted to 1 of 4 diets formulated to provide SID valine:lysine ratios of 50%, 60%, 70%, or 80%. Each diet was fed to 6 pens of pigs with 6 pigs per pen (3 gilts and 3 barrows for 28 days. Results Average daily gain increased quadratically (p<0.05, the villous height of the duodenum, jejunum and ileum increased linearly (p<0.05 as the SID valine:lysine ratio increased. The concentrations of plasma α-keto isovaleric and valine increased linearly (p<0.05, plasma aspartate, asparagine and cysteine decreased (p<0.05 as the SID valine:lysine ratio increased. An increase in SID lysine:valine levels increased mRNA expression levels of mitochondrial BCAA transaminase and branched-chain α-keto acid dehydrogenase in the longissimus dorsi muscle (p<0.05. Conclusion Using a quadratic model, a SID valine:lysine ratio of 68% was shown to maximize the growth of weaned pigs which is slightly higher than the level recommended by the National Research Council [6].

  12. Aerial Photography and Imagery, Ortho-Corrected, April 2012, color and b/w and NIR, tiff and MrSID, section tiles or countywide mosaic- plan to refly in 2017 at same resolution (6" pixel), Published in 2012, 1:1200 (1in=100ft) scale, Dodge County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Aerial Photography and Imagery, Ortho-Corrected dataset current as of 2012. April 2012, color and b/w and NIR, tiff and MrSID, section tiles or countywide mosaic-...

  13. The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer

    DEFF Research Database (Denmark)

    Mollenhauer, Jan; Müller, Hanna; Kollender, Gaby

    2002-01-01

    Deleted in malignant brain tumors 1 (DMBT1) at 10q25.3-q26.1 has been proposed as a candidate tumor-suppressor gene for brain and epithelial cancer. DMBT1 encodes a multifunctional mucin-like protein presumably involved in epithelial differentiation and protection. The gene consists of highly...... homologous and repeating exon and intron sequences. This specifically applies to the region coding for the repetitive scavenger receptor cysteine-rich (SRCR) domains and SRCR-interspersed domains (SIDs) that constitutes the major part of the gene. This particular structure may previously have interfered...... with the delineation of DMBT1 alterations in cancer. Uncovering these, however, is of mechanistic importance. By a combined approach, we conducted a detailed mutational analysis, starting from a panel of 51 tumors, including 46 tumor cell lines and five primary tumors. Alterations in the repetitive region were present...

  14. Effect of dietary soybean oil and soybean protein concentration on the concentration of digestible amino acids in soybean products fed to growing pigs.

    Science.gov (United States)

    Cervantes-Pahm, S K; Stein, H H

    2008-08-01

    An experiment was conducted to measure the effect of adding soybean oil to soybean meal (SBM) and soy protein concentrate (SPC) on apparent (AID) and standardized (SID) ileal digestibility of CP and AA by growing pigs. A second objective was to compare AID and SID of AA in a new high-protein variety of full fat soybeans (FFSB) to values obtained in other soybean products. Commercial sources of FFSB (FFSB-CV), SBM, and SPC, and of a new high-protein variety of FFSB (FFSB-HP) were used in the experiment. Four diets were prepared using each soybean product as the sole source of CP and AA in 1 diet. Two additional diets were formulated by adding soybean oil (7.55 and 7.35%, respectively) to the diets containing SBM and SPC. A nitrogen-free diet was also used to measure basal endogenous losses of CP and AA. The 2 sources of FFSB were extruded at 150 degrees C before being used in the experiment. Seven growing barrows (initial BW = 26.2 kg) were prepared with a T-cannula in the distal ileum and allotted to a 7 x 7 Latin square design. Ileal digesta were collected from the pigs on d 6 and 7 of each period. All digesta samples were lyophilized and analyzed for DM, CP, AA, and chromium, and values for AID and SID of CP and AA were calculated. The addition of oil improved (P oil and SPC, but these values were lower (P oil. In conclusion, the addition of oil improved the SID of most AA in SBM and SPC fed to growing pigs, and the SID of AA in FFSB-HP were greater than in SBM and similar to the SID of AA in SBM with oil and in SPC.

  15. The Lure of Authority: Motivation and Incentive Effects of Power

    OpenAIRE

    Fehr, Ernst; Herz, Holger; Wilkening, Tom

    2012-01-01

    Authority and power permeate political, social, and economic life, but empirical knowledge about the motivational origins and consequences of authority is limited. We study the motivation and incentive effects of authority experimentally in an authority delegation game. Individuals often retain authority even when its delegation is in their material interest—suggesting that authority has nonpecuniary consequences for utility. Authority also leads to over provision of effort by the controlling...

  16. Male and female WorldSID and post mortem human subject responses in full-scale vehicle tests.

    Science.gov (United States)

    Yoganandan, Narayan; Humm, John; Pintar, Frank; Rhule, Heather; Moorhouse, Kevin; Suntay, Brian; Stricklin, Jim; Rudd, Rodney; Craig, Matthew

    2017-05-29

    This study compares the responses of male and female WorldSID dummies with post mortem human subject (PMHS) responses in full-scale vehicle tests. Tests were conducted according to the FMVSS-214 protocols and using the U.S. Side Impact New Car Assessment Program change in velocity to match PMHS experiments, published earlier. Moving deformable barrier (MDB) tests were conducted with the male and female surrogates in the left front and left rear seats. Pole tests were performed with the male surrogate in the left front seat. Three-point belt restraints were used. Sedan-type vehicles were used from the same manufacturer with side airbags. The PMHS head was instrumented with a pyramid-shaped nine-axis accelerometer package, with angular velocity transducers on the head. Accelerometers and angular velocity transducers were secured to T1, T6, and T12 spinous processes and sacrum. Three chest bands were secured around the upper, middle, and lower thoraces. Dummy instrumentation included five infrared telescoping rods for assessment of chest compression (IR-TRACC) and a chest band at the first abdomen rib, head angular velocity transducer, and head, T1, T4, T12, and pelvis accelerometers. Morphological responses of the kinematics of the head, thoracic spine, and pelvis matched in both surrogates for each pair. The peak magnitudes of the torso accelerations were lower for the dummy than for the biological surrogate. The brain rotational injury criterion (BrIC) response was the highest in the male dummy for the MDB test and PMHS. The probability of AIS3+ injuries, based on the head injury criterion, ranged from 3% to 13% for the PMHS and from 3% to 21% for the dummy from all tests. The BrIC-based metrics ranged from 0 to 21% for the biological and 0 to 48% for the dummy surrogates. The deflection profiles from the IR-TRACC sensors were unimodal. The maximum deflections from the chest band placed on the first abdominal rib were 31.7 mm and 25.4 mm for the male and female

  17. Tobacco expenditure, smoking-induced deprivation and financial stress: results from the International Tobacco Control (ITC) Four-Country Survey.

    Science.gov (United States)

    Siahpush, Mohammad; Borland, Ron; Yong, Hua-Hie; Cummings, K Michael; Fong, Geoffrey T

    2012-07-01

    While higher tobacco prices lead to a reduction in smoking prevalence, there is a concern that paying more for cigarettes can lead to excess financial burden. Our primary aim was to examine the association of daily cigarette expenditure with smoking-induced deprivation (SID) and financial stress (FS). We used data from wave 7 (2008-2009) of the International Tobacco Control (ITC) Four-Country Survey which is a survey of smokers in Canada, the USA, the UK and Australia (n = 5887). Logistic regressions were used to assess the association of daily cigarette expenditure with SID and FS. In multivariate analyses, a one standard deviation increase in daily cigarette expenditure was associated with an increase of 24% (P = 0.004) in the probability of experiencing SID. While we found no association between daily cigarette expenditure and FS, we found that SID is a strong predictor of FS (odds ratio 6.25; P < 0.001). This suggests that cigarette expenditure indirectly affects FS through SID. Results showed no evidence of an interaction between cigarette expenditure and income or education in their effect on SID or FS. Our results imply that spending more on tobacco may result in SID but surprisingly has no direct effect on FS. While most smokers may be adjusting their incomes and consumption to minimise FS, some fail to do so occasionally as indexed by the SID measure. Future studies need to prospectively examine the effect of increased tobacco expenditure on financial burden of smokers. © 2012 Australasian Professional Society on Alcohol and other Drugs.

  18. Effects of the standardized ileal digestible lysine to metabolizable energy ratio on performance and carcass characteristics of growing-finishing pigs

    Directory of Open Access Journals (Sweden)

    Li Pengfei

    2012-03-01

    Full Text Available Abstract A total of 2,121 growing-finishing pigs (Duroc × Landrace × Large White were utilized in six experiments conducted to determine the effects of different ratios of standardized ileal digestible lysine (SID-Lys to metabolizable energy (ME on the performance and carcass characteristics of growing-finishing pigs. Exps. 1 (30 to 50 kg, 2 (52 to 70 kg and 3 (81 to 104 kg were conducted to find an optimum ME level and then this level was used in Exps. 4 (29 to 47 kg, 5 (54 to 76 kg and 6 (84 to 109 kg to test the response of pigs to different ratios of SID-Lys:ME. In Exps.1 to 3, four treatments were used consisting of diets with a formulated ME content of 3.1, 3.2, 3.3 or 3.4 in Exps. 1 and 2 while Exp. 3 used 3.05, 3.15, 3.25 or 3.35 Mcal/kg. A constant SID-Lys:ME ratio of 2.6, 2.3 or 2.0 g/Mcal was used in Exps. 1, 2 and 3, respectively. Weight gain was significantly increased with increasing energy level in Exp.1 while weight gain was unaltered in Exps. 2 and 3. For all three experiments, feed intake was decreased (P P P P P P

  19. Sudden infant death syndrome: how much mothers and health professionals know.

    Science.gov (United States)

    Yikilkan, Hulya; Unalan, Pemra Cobek; Cakir, Erkan; Ersu, Refika Hamutcu; Cifcili, Serap; Akman, Mehmet; Uzuner, Arzu; Dagli, Elif

    2011-02-01

    Behavioral risk factors are associated with sudden infant death syndrome (SIDS). Education about the risk factors of SIDS is important for prevention. Our aim was to determine the knowledge and attitude of parents and health professionals about SIDS. A total of 174 health professionals and 150 mothers were enrolled in this study. Mothers' data were collected by telephone interview and health-care professionals were interviewed by the same investigator. Only 39% of mothers were aware of SIDS. Forty-six percent of the mothers preferred a supine sleeping position for their infant and 16% of the parents were bed-sharing with their infants. Seventy-three percent of health professionals selected side, 17% supine and 10% prone sleeping position as the safest sleeping position. Frequencies for awareness of risk factors were: bed-sharing (75%), soft bedding (70%), pillow use (52%), toys in bed (90%), high room temperature (67%) and smoking (88%). Total knowledge score of health professionals who selected supine sleeping position as the safest was significantly higher (P sleeping position for their infant. Only 72% of health professionals recommended a certain sleeping position during family interviews. Health professionals are more often recommending the side sleeping position or prone. Education of families and health professionals for the risk factors of SIDS may reduce the number of deaths from SIDS in Istanbul. © 2011 The Authors. Pediatrics International © 2011 Japan Pediatric Society.

  20. Energy access and security strategies in Small Island Developing States

    International Nuclear Information System (INIS)

    Wolf, Franziska; Surroop, Dinesh; Singh, Anirudh; Leal, Walter

    2016-01-01

    Small Islands Developing States (SIDS) are isolated and surrounded by ocean. The generation and use of energy resources are two very important aspects for the development of SIDS. Unfortunately, most of SIDS do not use their potential in respect of energy resources, and they as a result have to depend on the import of fossil fuels in order to meet their energy needs. This increases the overall vulnerability of SIDS as they have to depend on the rising or fluctuating fossil fuels prices. Some SIDS, especially in the geographically dispersed Pacific region, do not have proper access to energy whereas other SIDS struggle more with energy security issue. At the same time, SIDS are most vulnerable to the impacts and effects of climate change, as they are among the ones to be most severely affected in case of natural calamities and sea-level rise. Drawing on experiences from Fiji and Mauritius, this paper explains core elements related to energy access and security in SIDS, contextualizes and discusses barriers and list some of the strategies that may be used to ensure access to and a continuous supply of energy in SIDS. A situational analysis of two SIDS outlines their current energy situation and compares their energy policies to globally accepted criteria for SIDS policies as well as with each other. It is claimed that the diverging energy performances of Fiji and Mauritius cannot be explained by policies differences. The reasons for the varying energy performances may therefore lie in the administrative and institutional mechanisms used by the two countries in implementing their energy policies. Finally, to enable SIDS to reduce their overall vulnerability and become truly sustainable islands, it is recommended to undertake careful assessments of the particular local contexts under which island energy regimes operate. - Highlights: • Core elements related to energy access/security in SIDS, barriers and strategies. • Situational analysis of two SIDS: Fiji and

  1. Political determinants of electricity provision in small island developing states

    International Nuclear Information System (INIS)

    Boräng, Frida; Jagers, Sverker C.; Povitkina, Marina

    2016-01-01

    This paper approaches provision of affordable and reliable electricity in Small Island Developing States (SIDS) as a case of public good provision. It aims to contribute to our understanding of how regime type and the quality of implementing institutions within political systems affect the prerequisites for successful electrification in SIDS. More specifically, we analyse the independent and interdependent effects of level of democracy and control of corruption on per capita household electricity consumption in SIDS, using data from 34 SIDS over the period 1996–2009. The results show that although the independent effects of level of democracy and control of corruption are sensitive to model specification, these two factors do have an interdependent impact on per capita household electricity consumption: democratization has positive effects on provision of electricity to the general population only when there is a certain level of corruption control in place. The results imply a) that it is important for policy actors to acknowledge the interaction between regime type and the quality of implementing institutions, and b) when planning electrification projects in SIDS, it is necessary to have information about the social and political context in order to design the most effective projects. - Highlights: • Effects of political institutions on household electricity consumption in SIDS. • Electrification is seen as an example of public good provision. • Democracy has a positive impact on electricity consumption when corruption is low. • Electrification projects can gain from being sensitive to institutional context.

  2. Effect of Different Inclusion Level of Condensed Distillers Solubles Ratios and Oil Content on Amino Acid Digestibility of Corn Distillers Dried Grains with Solubles in Growing Pigs

    Directory of Open Access Journals (Sweden)

    P. Li

    2015-01-01

    Full Text Available The purpose of this experiment was to determine and compare the digestibility of crude protein (CP and amino acids (AA in full-oil (no oil extracted and de-oiled (oil extracted corn distillers dried grains with solubles (DDGS with different condensed distillers solubles (CDS ratios. Six barrows (29.6±2.3 kg fitted with ileal T-cannula were allotted into a 6×6 Latin square design. Each period was comprised of a 5-d adaption period followed by a 2-d collection of ileal digesta. The five test diets contained 62% DDGS as the sole source of AA. A nitrogen-free diet was used to measure the basal endogenous losses of CP and AA. Chromic oxide (0.3% was used as an index in each diet. The results showed that CP and AA were very similar in 5 DDGS, but the standardized ileal digestibility (SID of lysine (from 56.16% to 71.15% and tryptophan (from 54.90% to 68.38% had the lowest values and largest variation within the essential AA, which suggests reduced availability of AA and different levels of Maillard reactions in the five DDGS. The apparent ileal digestibility and SID of CP and most of AA in full-oil DDGS (sources 1 and 2 were greater (p0.05 than full-oil with high CDS ratio DDGS (source 2; however, the SID of most AA of de-oiled with low CDS ratios DDGS (source 3 were non-significantly lower (p>0.05 than de-oiled with high CDS ratio DDGS (source 4; and the de-oiled DDGS with middle CDS ratio (source 5 but with different drying processing had the lowest SID AA values. In conclusion, de-oiled DDGS had lower SID of CP and AA than full-oil DDGS; a higher CDS ratio tended to decrease the SID of AA in full-oil DDGS but not in de-oiled DDGS; and compared with CDS ratio, processing, especially drying, may have more of an effect on AA digestibility of DDGS.

  3. De l’effet de sidération et de peur dans les autoportraits d’Andy Warhol

    Directory of Open Access Journals (Sweden)

    Marie CORDIÉ-LEVY

    2011-03-01

    Full Text Available Nous nous proposons d’analyser la sidération et la peur dans la dernière série d’autoportraits faite par Andy Warhol en 1986 qui donnent à voir les subterfuges de l’artiste pour en contrer ou en accompagner les effets. Après une première mise en perspective, nous avons tissé un réseau de correspondances serrées entre ces œuvres et le texte « Méduse et Compagnie » de Roger Caillois sur le travestissement, le camouflage et l’intimidation, en utilisant la micro-analyse tactile, technique inspirée de Carlo Ginzburg en histoire et d’Aloïs Riegl en histoire de l’art. Nous avons pu ainsi mettre en lumière comment, par le médium de la photographie ou de la sérigraphie, l’artiste s’est réinscrit tout en s’en démarquant, dans l’histoire visuelle de ceux qui, depuis Caravage, ont révolutionné le traitement de la peur dans l’image. Nous concluons en soulignant comment la spécificité américaine du cadrage y a introduit un autre rapport au réel.The following article analyses the way fear and shock appear in Andy Warhol’s last self portraits, produced in 1986, through the mechanisms that oppose and accompany it. Using the technique of the tactile micro-analysis inspired by historian Carlo Ginzburg and art historian Aloïs Riegl, we will attempt to decipher the effects of fear and shock by referring to the different stages defined by Roger Caillois as composing fear: travestissement, camouflage, and bullying. This representation of fear through the medium of photography and serigraphy simultaneously conforms to the tradition of the pictorial expressions of fear such as can be seen in Caravaggio, while also renewing the concept by introducing traits more typical of the American psyche: a close up view of the character and a touch of the surreal, which could be considered as the modern form of eternity.

  4. Sensory integration dysfunction affects efficacy of speech therapy on children with functional articulation disorders

    Directory of Open Access Journals (Sweden)

    Tung LC

    2013-01-01

    Full Text Available Li-Chen Tung,1,# Chin-Kai Lin,2,# Ching-Lin Hsieh,3,4 Ching-Chi Chen,1 Chin-Tsan Huang,1 Chun-Hou Wang5,6 1Department of Physical Medicine and Rehabilitation, Chi Mei Medical Center, Tainan, 2Program of Early Intervention, Department of Early Childhood Education, National Taichung University of Education, Taichung, 3School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, 4Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, 5School of Physical Therapy, College of Medical Science and Technology, Chung Shan Medical University, Taichung, 6Physical Therapy Room, Chung Shan Medical University Hospital, Taichung, Taiwan#These authors contributed equally Background: Articulation disorders in young children are due to defects occurring at a certain stage in sensory and motor development. Some children with functional articulation disorders may also have sensory integration dysfunction (SID. We hypothesized that speech therapy would be less efficacious in children with SID than in those without SID. Hence, the purpose of this study was to compare the efficacy of speech therapy in two groups of children with functional articulation disorders: those without and those with SID.Method: A total of 30 young children with functional articulation disorders were divided into two groups, the no-SID group (15 children and the SID group (15 children. The number of pronunciation mistakes was evaluated before and after speech therapy.Results: There were no statistically significant differences in age, sex, sibling order, education of parents, and pretest number of mistakes in pronunciation between the two groups (P > 0.05. The mean and standard deviation in the pre- and posttest number of mistakes in pronunciation were 10.5 ± 3.2 and 3.3 ± 3.3 in the no-SID group, and 10.1 ± 2.9 and 6.9 ± 3.5 in the SID group, respectively. Results showed great changes after speech therapy treatment (F

  5. Author's capabilities in author indexing

    International Nuclear Information System (INIS)

    Ooi, Shoichi

    1988-01-01

    The purpose of this paper is to provide a author capability of current author indexing practices in journal literature indexing practices in 'Journal of Nuclear Science and Technology of Japan'. This Journal employed keywords freely assigned by author and not taken from INIS Thesaurus or other vocabulary list. Author examined 413 literatures, comparing keywords assigned by the literatures' authors with descriptor's (ATOMINDEX) assigned by an experienced professional indexer. The results of the comparisons showed that the average set of terms assigned by author included about 70% of all the terms assigned to the same literature by the professional indexer. Authors eventually would contribute, for the most effective point to create reference to information is at the time of its generation. Consequently, it may be possible to transfer them easily to descriptors in every secondary information system. (author)

  6. Effect of processing of rapeseed under defined conditions in a pilot plant on chemical composition and standardized ileal amino acid digestibility in rapeseed meal for pigs.

    Science.gov (United States)

    Eklund, M; Sauer, N; Schöne, F; Messerschmidt, U; Rosenfelder, P; Htoo, J K; Mosenthin, R

    2015-06-01

    Five rapeseed meals (RSM) were produced from a single batch of rapeseed in a large-scale pilot plant under standardized conditions. The objective was to evaluate the effect of residence time in the desolventizer/toaster (DT) on chemical composition and standardized ileal digestibility (SID) of AA in RSM. Four RSM, with 48, 64, 76, and 93 min residence time and using unsaturated steam in the DT, referred to as RSM48, RSM64, RSM76, and RSM93, respectively, and 1 low-glucosinolate RSM, which was subjected to sequential treatment with unsaturated steam, saturated steam, and dry heat in the DT, referred to as low-GSL RSM, were assayed. Six barrows (average initial BW = 22 ± 1 kg) were surgically fitted with a T-cannula at the distal ileum. Pigs were allotted to a 5 × 6 row × column design with 5 diets and 5 periods. The 5 RSM were included in a cornstarch-casein-based basal diet. In addition, basal ileal endogenous losses and SID of AA originating from casein were determined at the conclusion of the experiment in 2 additional periods by means of the regression method and using 3 graded levels of casein. The SID of AA in the 5 RSM was determined in difference to SID of AA originating from casein. The glucosinolates (GSL) were efficiently reduced, whereas NDF, ADF, ADL, and NDIN contents increased and reactive Lys (rLys) and Lys:CP ratio decreased as the residence time in the DT was increased from 48 to 93 min. The SID of most AA in RSM linearly decreased (P based on content of NDIN, GSL, rLys or on Lys:CP ratio, in different batches of RSM used for feed manufacturing.

  7. Differential control of central cardiorespiratory interactions by hypercapnia and the effect of prenatal nicotine.

    Science.gov (United States)

    Huang, Zheng-Gui; Griffioen, Kathleen J S; Wang, Xin; Dergacheva, Olga; Kamendi, Harriet; Gorini, Christopher; Bouairi, Euguenia; Mendelowitz, David

    2006-01-04

    Hypercapnia evokes a strong cardiorespiratory response including gasping and a pronounced bradycardia; however, the mechanism responsible for these survival responses initiated in the brainstem is unknown. To examine the effects of hypercapnia on the central cardiorespiratory network, we used an in vitro medullary slice that allows simultaneous examination of rhythmic respiratory-related activity and inhibitory synaptic neurotransmission to cardioinhibitory vagal neurons (CVNs). Hypercapnia differentially modulated inhibitory neurotransmission to CVNs; whereas hypercapnia selectively depressed spontaneous glycinergic IPSCs in CVNs without altering respiratory-related increases in glycinergic neurotransmission, it decreased both spontaneous and inspiratory-associated GABAergic IPSCs. Because maternal smoking is the highest risk factor for sudden infant death syndrome (SIDS) and prenatal nicotine exposure is proposed to be the link between maternal smoking and SIDS, we examined the cardiorespiratory responses to hypercapnia in animals exposed to nicotine in the prenatal and perinatal period. In animals exposed to prenatal nicotine, hypercapnia evoked an exaggerated depression of GABAergic IPSCs in CVNs with no significant change in glycinergic neurotransmission. Hypercapnia altered inhibitory neurotransmission to CVNs at both presynaptic and postsynaptic sites. Although the results obtained in this study in vitro cannot be extrapolated with certainty to in vivo responses, the results of this study provide a likely neurochemical mechanism for hypercapnia-evoked bradycardia and the dysregulation of this response with exposure to prenatal nicotine, creating a higher risk for SIDS.

  8. Effectiveness of author-assigned keywords to INIS indexing

    International Nuclear Information System (INIS)

    Yokoo, Hiroshi; Takahashi, Satoko; Habara, Tadashi

    1977-01-01

    A test was carried out on the quality of indexing data which is based only upon author-assigned keywords in order to appreciate effectiveness of the keywords. As measures of the quality, the retrievability and the consistency of the indexing data were evaluated by comparison with the case of the conventional indexing method under the circumstances of the INIS descriptor assignment to the journal articles of the Atomic Energy Society of Japan. The indexing consistency obtained was approximately 0.61 on an average (or 0.66 when the narrower-broader hierarchical relations were regarded as consistent ones). Of the hit, noise, or total documents retrieved with the conventional indexing data, 0.86, 0.27, or 0.71, respectively, were retrievable with the keywords-based indexing data. From the results the recall ratio for the keywords-based indexing is estimated to be no less than 0.86 of that for the conventional indexing method, and the consistency of the hit documents are to be 0.75 at least. Consequently, the author-assigned keywords proved to be very effective to the document indexing. (auth.)

  9. 31 CFR 543.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 543.502 Section 543.502 Money and Finance: Treasury Regulations Relating to Money and Finance... principles of law. ...

  10. 31 CFR 575.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 575.501 Section 575.501 Money and Finance: Treasury Regulations Relating to Money and Finance... principles of law. ...

  11. 31 CFR 546.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 546.502 Section 546.502 Money and Finance: Treasury Regulations Relating to Money and Finance... principles of law. ...

  12. 31 CFR 538.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 538.501 Section 538.501 Money and Finance: Treasury Regulations Relating to Money and Finance... principles of law. ...

  13. 31 CFR 537.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 537.502 Section 537.502 Money and Finance: Treasury Regulations Relating to Money and Finance... principles of law. ...

  14. Analytical Evaluation and Antioxidant Properties of Some Secondary Metabolites in Northern Italian Mono- and Multi-Varietal Extra Virgin Olive Oils (EVOOs) from Early and Late Harvested Olives.

    Science.gov (United States)

    Trombetta, Domenico; Smeriglio, Antonella; Marcoccia, Daniele; Giofrè, Salvatore Vincenzo; Toscano, Giovanni; Mazzotti, Fabio; Giovanazzi, Angelo; Lorenzetti, Stefano

    2017-04-11

    The antioxidant activity and the phenolic and α-tocopherol content of 10 Northern Italian mono- and multi-varietal extra virgin olive oils (EVOOs), after early and late olive harvests, was analyzed. A hierarchical cluster analysis was used to evaluate sample similarity. Secoiridoids (SIDs), lignans and flavonoids were the most abundant phenolic compounds identified. The organic Casaliva (among mono-cultivar) and the organic multi-varietal (among blended oils) EVOOs had the higher total phenol content both in early (263.13 and 326.19 mg/kg, respectively) and late harvest (241.88 and 292.34 mg/kg, respectively) conditions. In comparison to late harvest EVOOs, early harvest EVOOs, in particular the organic mono-cultivar Casaliva, showed both higher antioxidant capacity (up to 1285.97 Oxygen Radicals Absorbance Capacity/ORAC units), probably due to the higher SID fraction (54% vs. 40%), and higher α-tocopherol content (up to 280.67 mg/kg). Overall, these results suggest that SIDs and α-tocopherol mainly contribute to antioxidant properties of the studied EVOOs. In light of this, the authors conclude that early harvest, organic mono-cultivar Casaliva EVOO represents the most interesting candidate to explicate healthy effects ascribed to these functional constituents, particularly regarding oxidative stress-related pathologies.

  15. Traceability in food supply chains Exploring governmental authority and industrial effects

    OpenAIRE

    Ringsberg, Henrik

    2011-01-01

    Traceability in food supply chains has received increased attention in the last decade. The efforts of governmental authorities have also increased to regulate and control food supply chains and product characteristics related to information to ensure safety, quality, and preservation of living resources. Previous studies in the area take an industrial focus and exclude the governmental authority focus. This thesis thus focuses on exploring governmental authority and industrial effects on tra...

  16. 12 CFR 707.1 - Authority, purpose, coverage and effect on State laws.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Authority, purpose, coverage and effect on... AFFECTING CREDIT UNIONS TRUTH IN SAVINGS § 707.1 Authority, purpose, coverage and effect on State laws. (a... National Credit Union Administration. In addition, the advertising rules in § 707.8 apply to any person who...

  17. 12 CFR 230.1 - Authority, purpose, coverage, and effect on state laws.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Authority, purpose, coverage, and effect on..., and effect on state laws. (a) Authority. This part, known as Regulation DD, is issued by the Board of... advertising rules in § 230.8 of this part apply to any person who advertises an account offered by a...

  18. 31 CFR 536.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 536.501 Section 536.501 Money and Finance: Treasury Regulations Relating to Money and Finance... exist under ordinary principles of law. ...

  19. 31 CFR 595.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 595.501 Section 595.501 Money and Finance: Treasury Regulations Relating to Money and Finance... exist under ordinary principles of law. ...

  20. 31 CFR 540.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 540.501 Section 540.501 Money and Finance: Treasury Regulations Relating to Money and Finance... otherwise exist under ordinary principles of law. ...

  1. 31 CFR 593.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 593.502 Section 593.502 Money and Finance: Treasury Regulations Relating to Money and Finance... otherwise exist under ordinary principles of law. ...

  2. 31 CFR 585.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 585.501 Section 585.501 Money and Finance: Treasury Regulations Relating to Money and Finance... not otherwise exist under ordinary principles of law. ...

  3. 31 CFR 597.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 597.501 Section 597.501 Money and Finance: Treasury Regulations Relating to Money and Finance... not otherwise exist under ordinary principles of law. ...

  4. 31 CFR 587.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 587.502 Section 587.502 Money and Finance: Treasury Regulations Relating to Money and Finance... not otherwise exist under ordinary principles of law. ...

  5. 31 CFR 547.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 547.502 Section 547.502 Money and Finance: Treasury Regulations Relating to Money and Finance... otherwise exist under ordinary principles of law. ...

  6. 31 CFR 544.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 544.502 Section 544.502 Money and Finance: Treasury Regulations Relating to Money and Finance... not otherwise exist under ordinary principles of law. ...

  7. Targeted repression of AXIN2 and MYC gene expression using designer TALEs

    International Nuclear Information System (INIS)

    Rennoll, Sherri A.; Scott, Samantha A.; Yochum, Gregory S.

    2014-01-01

    Highlights: • We designed TALE–SID fusion proteins to target AXIN2 and MYC. • TALE–SIDs bound the chromosomal AXIN2 and MYC genes and repressed their expression. • TALE–SIDs repress β-catenin S45F -dependent AXIN2 and MYC transcription. - Abstract: Designer TALEs (dTALEs) are chimeric transcription factors that can be engineered to regulate gene expression in mammalian cells. Whether dTALEs can block gene transcription downstream of signal transduction cascades, however, has yet to be fully explored. Here we tested whether dTALEs can be used to target genes whose expression is controlled by Wnt/β-catenin signaling. TALE DNA binding domains were engineered to recognize sequences adjacent to Wnt responsive enhancer elements (WREs) that control expression of axis inhibition protein 2 (AXIN2) and c-MYC (MYC). These custom DNA binding domains were linked to the mSin3A interaction domain (SID) to generate TALE–SID chimeric repressors. The TALE–SIDs repressed luciferase reporter activity, bound their genomic target sites, and repressed AXIN2 and MYC expression in HEK293 cells. We generated a novel HEK293 cell line to determine whether the TALE–SIDs could function downstream of oncogenic Wnt/β-catenin signaling. Treating these cells with doxycycline and tamoxifen stimulates nuclear accumulation of a stabilized form of β-catenin found in a subset of colorectal cancers. The TALE–SIDs repressed AXIN2 and MYC expression in these cells, which suggests that dTALEs could offer an effective therapeutic strategy for the treatment of colorectal cancer

  8. Targeted repression of AXIN2 and MYC gene expression using designer TALEs

    Energy Technology Data Exchange (ETDEWEB)

    Rennoll, Sherri A.; Scott, Samantha A.; Yochum, Gregory S., E-mail: gsy3@psu.edu

    2014-04-18

    Highlights: • We designed TALE–SID fusion proteins to target AXIN2 and MYC. • TALE–SIDs bound the chromosomal AXIN2 and MYC genes and repressed their expression. • TALE–SIDs repress β-catenin{sup S45F}-dependent AXIN2 and MYC transcription. - Abstract: Designer TALEs (dTALEs) are chimeric transcription factors that can be engineered to regulate gene expression in mammalian cells. Whether dTALEs can block gene transcription downstream of signal transduction cascades, however, has yet to be fully explored. Here we tested whether dTALEs can be used to target genes whose expression is controlled by Wnt/β-catenin signaling. TALE DNA binding domains were engineered to recognize sequences adjacent to Wnt responsive enhancer elements (WREs) that control expression of axis inhibition protein 2 (AXIN2) and c-MYC (MYC). These custom DNA binding domains were linked to the mSin3A interaction domain (SID) to generate TALE–SID chimeric repressors. The TALE–SIDs repressed luciferase reporter activity, bound their genomic target sites, and repressed AXIN2 and MYC expression in HEK293 cells. We generated a novel HEK293 cell line to determine whether the TALE–SIDs could function downstream of oncogenic Wnt/β-catenin signaling. Treating these cells with doxycycline and tamoxifen stimulates nuclear accumulation of a stabilized form of β-catenin found in a subset of colorectal cancers. The TALE–SIDs repressed AXIN2 and MYC expression in these cells, which suggests that dTALEs could offer an effective therapeutic strategy for the treatment of colorectal cancer.

  9. A COMMUNITY BASED RANDOMIZED CONTROLLED TRIAL OF IRON AND ZINC SUPPLEMENTATION IN INFANTS: EFFECTS ON GROWTH AND DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    T. Lind

    2006-01-01

    Full Text Available Deficiencies of iron and zinc are associated with delayed development, growth faltering, and increased infectious disease morbidity during infancy and childhood. Combined iron and zinc supplementation may therefore be a logical preventive strategy. Objective: the objective of the study was to compare the effects of combined iron and zinc supplementation in infancy with the effects of iron and zinc as single micronutrients on growth, psychomotor development, and incidence of infectious disease. Design: Indonesian infants (n = 680 were randomly assigned to daily supplementation with 10 mg Fe (Fe group, 10 mg Zn (Zn group, 10 mg Fe and 10 mg Zn (Fe + Zn group, or placebo from 6 to 12 mo of age. Anthropometric indexes, developmental indexes (bay ley scales of infant development; sid, and morbidity were recorded. Results: at 12 mo, two factor analysis of variance showed a significant interaction between Iron and Zinc for weight for age z score, knee heel length, and sid psychomotor development. Weight forage z score was higher in the Zn group than in the placebo and Fe + Zn groups, knee heel length was higher in the Zn and Fe groups than in the placebo group, and the sid psychomotor development index was higher in the Fe group than in the placebo group. No significant effect on morbidity was found. Conclusions: single supplementation with zinc significantly improved growth, and single supplementation with iron significantly improved growth and psychomotor development, but combined supplementation with iron and zinc had no significant effect on growth or development. Combined, simultaneous supplementation with iron and zinc to infants cannot be routinely recommended at the iron to zinc ratio used in this study.Key words: infants, growth, knee heel length, development, iron, zinc.

  10. 31 CFR 548.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 548.502 Section 548.502 Money and Finance: Treasury Regulations Relating to Money and Finance... property which would not otherwise exist under ordinary principles of law. ...

  11. Application of K0-NAA in the Determination of Gold and other Trace Elements in Mineralized Rocks from El-Sid Gold District, Eastern Desert, Egypt

    International Nuclear Information System (INIS)

    El Abd, A.; Hamdy, M.; Mostafa, M.; El-Amir, M.

    2009-01-01

    K 0 - neutron activation analysis is an important method for multi-element analysis . The NAA k - 0 was used to determine the concentration of gold and some other trace elements in the mineralized mafic (gabro) and ultramafic (serpentinite) rocks from El-Sid gold district, Central Eastern Desert, Egypt . The samples were properly prepared together with the standards Au, Zr and Ni and simultaneously irradiated in the irradiation position 2, which is characterized with the neutron spectrum parameters a = -0.01 and f =20. After activation, the samples were subjected to gamma-ray spectrometry, using a high-purity germanium detection system and computerized multichannel analyzer. The concentrations of 25 elements, beside gold were determined. The results showed that the concentrations of incompatible elements including rare earth elements, large-ion lithophile elements (Rb, Sr, Th, Ba, Cs and Na) and high field strength elements (Ta, Hf and Zr), and the compatible elements (transition elements Co and Cr) are different from one sample to another. The results were briefly discussed within the text of this research work.

  12. Changing author counts in five major general medicine journals: effect of author contribution forms.

    Science.gov (United States)

    Baerlocher, Mark Otto; Gautam, Tina; Newton, Marshall; Tomlinson, George

    2009-08-01

    Objective and indirect evidence was used to determine whether required author contribution forms were associated with a decrease in author counts in four major general medicine journals (British Medical Journal [BMJ], Journal of the American Medical Association [JAMA], Canadian Medical Association Journal [CMAJ], and the Lancet). The number of authors listed per article before and after the introduction of explicit author contribution requirements were counted and compared with that found for the New England Journal of Medicine (NEJM) that did not require such disclosure. The primary hypothesis was that author counts decreased more in the BMJ, CMAJ, JAMA, and the Lancet after introduction of the rules than they did in the NEJM. The number of authors listed per original research article published in the five general medical journals with the greatest 2004 Impact Factors in the first issue of each month in the years before and after introduction of required author contribution forms was compared. Introduction of the required author contribution forms by the four leading general medical journals did not result in a drop in the rate of increasing authors per article per year, or in the number of authors per article compared with the control. Overall, there was a trend of an increasing number of authors listed per article. Based on the presented objective and indirect evidence, required author contribution forms were not associated with a decrease in author counts.

  13. Human papillomavirus vaccine uptake among individuals with systemic inflammatory diseases.

    Directory of Open Access Journals (Sweden)

    Candace H Feldman

    Full Text Available The human papillomavirus (HPV vaccine is safe and efficacious in patients with systemic inflammatory diseases (SID who have higher rates of persistent HPV infection. We compared HPV vaccine uptake among SID and non-SID patients.Using a U.S. insurance claims database (2006-2012, we identified individuals 9-26 years with ≥2 SID diagnosis codes ≥7 days apart with ≥12 months of continuous enrollment prior to the second code (index date. We matched SID patients by age, sex and index date to randomly selected non-SID subjects and selected those with ≥24 months of post-index date continuous follow-up. We also identified a non-SID subcohort with ≥1 diagnosis code for asthma. We defined initiation as ≥1 HPV vaccination claim after 2007, and completion as 3 claims. We used multivariable logistic regression to assess uptake in females 11-26 years comparing SID, non-SID and asthma cohorts, adjusting for demographics, region, comorbidities, and healthcare utilization.We identified 5,642 patients 9-26 years with SID and 20,643 without. The mean age was 18.1 years (SD 4.9. We identified 1,083 patients with asthma; the mean age was 17.2 (SD 5.1. Among females, 20.6% with SID, 23.1% without SID and 22.9% with asthma, received ≥1 HPV vaccine. In our adjusted models, the odds of receipt of ≥1 vaccine was 0.87 times lower in SID (95% CI 0.77-0.98 compared to non-SID and did not differ for 3 vaccines (OR 1.03, 95% CI 0.83-1.26. The odds of initiation and completion were not statistically different between SID and non-SID asthma cohorts.In this nationwide cohort, HPV vaccine uptake was extremely low. Despite the heightened risk of persistent HPV infection among those with SID, no increase in HPV vaccine uptake was observed. Public health efforts to promote HPV vaccination overall are needed, and may be particularly beneficial for those at higher risk.

  14. 31 CFR 560.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 560.501 Section 560.501 Money and Finance: Treasury Regulations Relating to Money and Finance... respect to, any property which would not otherwise exist under ordinary principles of law. (d) Specific...

  15. 31 CFR 535.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 535.502 Section 535.502 Money and Finance: Treasury Regulations Relating to Money and Finance... respect to, any property which would not otherwise exist under ordinary principles of law. [44 FR 66833...

  16. 31 CFR 594.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 594.502 Section 594.502 Money and Finance: Treasury Regulations Relating to Money and Finance... interest in, or with respect to, any property which would not otherwise exist under ordinary principles of...

  17. 31 CFR 588.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 588.502 Section 588.502 Money and Finance: Treasury Regulations Relating to Money and Finance... interest in, or with respect to, any property which would not otherwise exist under ordinary principles of...

  18. 31 CFR 596.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 596.501 Section 596.501 Money and Finance: Treasury Regulations Relating to Money and Finance... interest in, or with respect to, any property which would not otherwise exist under ordinary principles of...

  19. 31 CFR 542.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 542.502 Section 542.502 Money and Finance: Treasury Regulations Relating to Money and Finance... interest in, or with respect to, any property which would not otherwise exist under ordinary principles of...

  20. 31 CFR 545.501 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 545.501 Section 545.501 Money and Finance: Treasury Regulations Relating to Money and Finance... interest in, or with respect to, any property which would not otherwise exist under ordinary principles of...

  1. 31 CFR 586.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 586.502 Section 586.502 Money and Finance: Treasury Regulations Relating to Money and Finance... property which would not otherwise exist under ordinary principles of law. Note to paragraph (c) of § 586...

  2. 31 CFR 541.502 - Effect of license or authorization.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effect of license or authorization. 541.502 Section 541.502 Money and Finance: Treasury Regulations Relating to Money and Finance... interest in, or with respect to, any property which would not otherwise exist under ordinary principles of...

  3. Human Papillomavirus Vaccine Uptake among Individuals with Systemic Inflammatory Diseases

    Science.gov (United States)

    Feldman, Candace H.; Hiraki, Linda T.; Lii, Huichuan; Seeger, John D.; Kim, Seoyoung C.

    2015-01-01

    Objectives The human papillomavirus (HPV) vaccine is safe and efficacious in patients with systemic inflammatory diseases (SID) who have higher rates of persistent HPV infection. We compared HPV vaccine uptake among SID and non-SID patients. Methods Using a U.S. insurance claims database (2006–2012), we identified individuals 9–26 years with ≥2 SID diagnosis codes ≥7 days apart with ≥12 months of continuous enrollment prior to the second code (index date). We matched SID patients by age, sex and index date to randomly selected non-SID subjects and selected those with ≥24 months of post-index date continuous follow-up. We also identified a non-SID subcohort with ≥1 diagnosis code for asthma. We defined initiation as ≥1 HPV vaccination claim after 2007, and completion as 3 claims. We used multivariable logistic regression to assess uptake in females 11–26 years comparing SID, non-SID and asthma cohorts, adjusting for demographics, region, comorbidities, and healthcare utilization. Results We identified 5,642 patients 9–26 years with SID and 20,643 without. The mean age was 18.1 years (SD 4.9). We identified 1,083 patients with asthma; the mean age was 17.2 (SD 5.1). Among females, 20.6% with SID, 23.1% without SID and 22.9% with asthma, received ≥1 HPV vaccine. In our adjusted models, the odds of receipt of ≥1 vaccine was 0.87 times lower in SID (95% CI 0.77–0.98) compared to non-SID and did not differ for 3 vaccines (OR 1.03, 95% CI 0.83–1.26). The odds of initiation and completion were not statistically different between SID and non-SID asthma cohorts. Conclusions In this nationwide cohort, HPV vaccine uptake was extremely low. Despite the heightened risk of persistent HPV infection among those with SID, no increase in HPV vaccine uptake was observed. Public health efforts to promote HPV vaccination overall are needed, and may be particularly beneficial for those at higher risk. PMID:25692470

  4. The Effects of Age, Authority, and Gender on Perceptions of Statutory Rape Offenders

    Science.gov (United States)

    Sahl, Daniel; Keene, Jennifer Reid

    2012-01-01

    Using a sample of 2,838 students from a Southwestern university in the United States, the authors examine the effect of respondent's gender, the adult's gender, the age gap between the adult and teen, and the adult's authority, on students' perceptions of vignettes describing adult-teen sexual relationships. Specifically, the authors investigate…

  5. [The phenomenon of the inducement of demand and various concepts in the economics of health].

    Science.gov (United States)

    Renckens, An; Decaluwe, Frida

    2006-01-01

    The article looks at the behaviour of practitioners and patients from an economic point of view, in particular at supplier-induced demand (SID). The objective is to be able to describe the factors which impact on the market for health care. To define the market for health care/dental care in general and the SID concept in particular, the following economic terminology is relevant. uncertainty, asymmetric information, moral hazard, and the agency relationship between practitioner and patient. Essentially SID results from the existence of asymmetric information (information "gap") on the health care market. The patient is less informed than the practitioner and cannot accurately assess his need for medical care. Hence decision-making authority is delegated to the practitioner who acts as the patient's agent to determine the optimal (amount of) care. This enables the practitioner to influence the demand for medical/dental care. If the practitioner is more interested in the rate of return than in the patient s need for care, a difference might arise between the care recommended by the practitioner and the care the patient would have asked for if he had the same level of information as the practitioner. This difference is called the amount of SID.

  6. Parameter study for child injury mitigation in near-side impacts through FE simulations.

    Science.gov (United States)

    Andersson, Marianne; Pipkorn, Bengt; Lövsund, Per

    2012-01-01

    The objective of this study is to investigate the effects of crash-related car parameters on head and chest injury measures for 3- and 12-year-old children in near-side impacts. The evaluation was made using a model of a complete passenger car that was impacted laterally by a barrier. The car model was validated in 2 crash conditions: the Insurance Institute for Highway Safety (IIHS) and the US New Car Assessment Program (NCAP) side impact tests. The Small Side Impact Dummy (SID-IIs) and the human body model 3 (HBM3) (Total HUman Model for Safety [THUMS] 3-year-old) finite element models were used for the parametric investigation (HBM3 on a booster). The car parameters were as follows: vehicle mass, side impact structure stiffness, a head air bag, a thorax-pelvis air bag, and a seat belt with pretensioner. The studied dependent variables were as follows: resultant head linear acceleration, resultant head rotational acceleration, chest viscous criterion, rib deflection, and relative velocity at head impact. The chest measurements were only considered for the SID-IIs. The head air bag had the greatest effect on the head measurements for both of the occupant models. On average, it reduced the peak head linear acceleration by 54 g for the HBM3 and 78 g for the SID-IIs. The seat belt had the second greatest effect on the head measurements; the peak head linear accelerations were reduced on average by 39 g (HBM3) and 44 g (SID-IIs). The high stiffness side structure increased the SID-IIs' head acceleration, whereas it had marginal effect on the HBM3. The vehicle mass had a marginal effect on SID-IIs' head accelerations, whereas the lower vehicle mass caused 18 g higher head acceleration for HBM3 and the greatest rotational acceleration. The thorax-pelvis air bag, vehicle mass, and seat belt pretensioner affected the chest measurements the most. The presence of a thorax-pelvis air bag, high vehicle mass, and a seat belt pretensioner all reduced the chest viscous criterion

  7. INVESTIGATION AUTHORITIES OF FINANCIAL SERVICES AUTHORITY IN SYARIAH BANKING

    Directory of Open Access Journals (Sweden)

    Hamsir

    2015-01-01

    Full Text Available This paper aims to explore the authority of the FSA as one of the institutions that deal with crime investigation in banking institutions, especially in Islamic Banking. Investigators FSA has great authority other than the authority to conduct investigations that are not owned by other investigators. The existence of this authority would lead to overlapping investigation with a given investigation agencies such as the police and the prosecutor. Fundamental problems are experienced by the FSA in conducting the investigation is less availability of human resources of FSA investigator. Therefore, inevitably required cooperation with the Police in effecting the FSA investigation. Effectiveness of investigations conducted by the FSA task for banking crimes that occurred in Islamic Banking is need synergy of communication and coordination with the DSN as an institution authorized by the Islamic Banking Act to provide recommendations to other agencies including the FSA if there is suspicion of a criminal offense in Islamic Banking.

  8. The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron.

    Science.gov (United States)

    Reiber, Kathrin; Reeves, Emer P; Neville, Claire M; Winkler, Robert; Gebhardt, Peter; Kavanagh, Kevin; Doyle, Sean

    2005-07-01

    Three non-ribosomal peptide synthetase genes, termed sidD, sidC and sidE, have been identified in Aspergillus fumigatus. Gene expression analysis by RT-PCR confirms that expression of both sidD and C was reduced by up to 90% under iron-replete conditions indicative of a likely role in siderophore biosynthesis. SidE expression was less sensitive to iron levels. In addition, two proteins purified from mycelia grown under iron-limiting conditions corresponded to SidD ( approximately 200 kDa) and SidC (496 kDa) as determined by MALDI ToF peptide mass fingerprinting and MALDI LIFT-ToF/ToF. Siderophore synthetases are unique in bacteria and fungi and represent an attractive target for antimicrobial chemotherapy.

  9. The importance of a forensics investigation of sudden infant death syndrome: recommendations for developing, low and middle income countries

    Directory of Open Access Journals (Sweden)

    Steven A. Koehler

    2010-11-01

    Full Text Available Sudden infant deaths syndrome (SIDS, the sudden and unexpected death of a normal and healthy infant, has remained a medical and forensic mystery. Despite years of research all attempts to ascertain the exact cause and manner of death have failed. The information collected during the course of the comprehensive investigation by the various investigation agencies and analysis of the data has not been in vain. The epidemiological, demographic, and pathological data have identified distinctive features and risk factors associated with infants that died from SIDS. Epidemiological data has provided the unique characteristics of infants that died of SIDS that differentiates them from non-SIDS infants. Analysis of information from the death scene investigation has identified key risk factor behaviour associated with SIDS, namely the prone sleeping position. Pathological examination of the internal organs, specifically the brain, has shown some differences between SIDS and non-SIDS infants. However, to gain a complete picture of SIDS data, all countries around the world must provide information, even basic information, to understand this syndrome better. Developing countries must understand their role and importance in developing plans to investigate, collect, and disseminate SIDS data to the rest of the world. This paper provides general guidelines for the investigation of SIDS in developing countries.

  10. Phrenic nerves and diaphragms in sudden infant death syndrome.

    Science.gov (United States)

    Weis, J; Weber, U; Schröder, J M; Lemke, R; Althoff, H

    1998-01-30

    Disturbances of the respiratory system may be an important factor in the cascade of events leading to sudden infant death syndrome (SIDS). Even though the diaphragm is the major respiratory muscle in infants, little is known about alterations of this muscle and of the phrenic nerve in SIDS. In the present study, diaphragms and phrenic nerves of 24 SIDS infants and seven controls were analyzed. Morphometric analysis revealed only slightly larger cross sectional areas of phrenic nerve axons but no increase in myelin sheath thickness in SIDS cases. However, in one SIDS case, myelinated nerve fibre density was severely reduced. Using electron microscopy, several nerve fibres of SIDS infants showed focal accumulations of neurofilaments. Muscle fibre diameters in SIDS diaphragms were significantly larger compared to controls (P fibre ruptures and contracture bands were found. These prominent nonspecific ultrastructural alterations should advise caution in the interpretation of morphometric data. Thus, in some cases exemplified by one case of the present series, decreased density of phrenic nerve myelinated axons might contribute to SIDS. Still, the present results indicate that development of phrenic nerves and diaphragms is not delayed in most SIDS infants.

  11. Cardiac channelopathies and sudden infant death syndrome

    DEFF Research Database (Denmark)

    Tfelt-Hansen, Jacob; Winkel, Bo Gregers; Grunnet, Morten

    2011-01-01

    Sudden infant death syndrome (SIDS) is always a devastating and unexpected occurrence. SIDS is the leading cause of death in the first 6 months after birth in the industrialized world. Since the discovery in 1998 of long QT syndrome as an underlying substrate for SIDS, around 10-20% of SIDS cases...

  12. A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, Jiazhang; Yu, Kaiwen; Fei, Xiaowen; Liu, Yao; Nakayasu, Ernesto S.; Piehowski, Paul D.; Shaw, Jared B.; Puvar, Kedar; Das, Chittaranjan; Liu, Xiaoyun; Luo, Zhao-Qing

    2017-05-12

    Ubiquitination regulates many aspects of host immunity and thus is a common target for infectious agents. Recent studies revealed that members of the SidE effector family of the bacterial pathogen Legionella pneumophila attacked several small GTPases associated with the endoplasmic reticulum by a novel ubiquitination mechanism that does not require the E1 and E2 enzymes of the host ubiquitination machinery. Following ubiquitin activation by ADP- ribosylation via a mono-ADP-ribosylation motif, ADP-ribosylated ubiquitin is cleaved by a phosphodiesterasedomainwithinSdeA,whichisconcomitantwiththelinkof phosphoribosylated ubiquitin to serine residues in the substrate. Here we demonstrate that the activity of SidEs is regulated by SidJ, another effector encoded by a gene situated in the locus coding for three members of the SidE family (SdeC, SdeB and SdeA). SidJ functions to remove ubiquitin from SidEs-modified substrates by cleaving the phosphodiester bond that links phosphoribosylated ubiquitin to protein substrates. Further, the deubiquitinase activity of SidJ is essential for its role in L. pneumophila infection. Finally, the activity of SidJ is required for efficiently reducing the abundance of ubiquitinated Rab33b in infected cells within a few hours after bacterial uptake. Our results establish SidJ as a deubiquitinase that functions to impose temporal regulation of the activity of the SidE effectors. The identification of SidJ may shed light on future study of signaling cascades mediated by this unique ubiquitination that also potentially regulates cellular processes in eukaryotic cells.

  13. Theorethical principles of fluid managment according to physicochemical Stewart approach.

    Science.gov (United States)

    Smuszkiewicz, Piotr; Szrama, Jakub

    2013-01-01

    Interpreting acid base disturbances according to the physicochemical Stewart approach allows the cause of such abnormalities to be discovered. This method is based on three independent variables: SID (strong ion difference), mainly sodium and chloride; weak acids concentration - Atot, mainly albumins and phosphate; and carbon dioxide tension - pCO₂. These three independent variables are responsible for the change of water dissociation and for the change in H+ concentration and, consequently, the change in serum pH value. The SID value of the fluids administered to a patient is responsible for the change of serum SID value and therefore causes a change in the patient's acid base status. During the infusion of a given fluid, the SID value of the serum becomes closer to the SID value of that fluid; on the other hand, the infusion causes a decrease in Atot concentration. In order to avoid acid base disturbances connected with fluid administration, the SID value of fluids being administered should be greater than 0 and lower then the serum SID. It has been suggested that fluids should be given of which the SID value is as close as possible to the actual serum HCO₃ concentration. Knowing the SID value of the fluid administered, and the serum HCO₃ concentration, one can expect a change of serum pH after a fluid infusion. Administering a fluid with a SID greater than the HCO₃ concentration causes a pH increase towards alkalosis. Likewise, administering a a fluid with a SID lower than the HCO₃ concentration causes a pH decrease towards acidosis. It seems that knowledge of the electrolyte concentration and the SID value of an administered fluid is an important factor regarding acid base disturbances.

  14. Current status of solid waste management in small island developing states: A review.

    Science.gov (United States)

    Mohee, Romeela; Mauthoor, Sumayya; Bundhoo, Zumar M A; Somaroo, Geeta; Soobhany, Nuhaa; Gunasee, Sanjana

    2015-09-01

    This article reviews the current status of waste management in Small Island Developing States (SIDS) and the challenges that are faced in solid waste management. The waste generation rates of SIDS were compared within the three geographic regions namely Caribbean SIDS, Pacific SIDS and Atlantic, Indian Ocean, Mediterranean and South China (AIMS) SIDS and with countries of the Organisation for Economic Co-Operation and Development (OECD). Only Pacific SIDS had a waste generation rate less than 1kg/capita/day. The waste generation rates for the three SIDS regions averaged 1.29kg/capita/day while that for OECD countries was at a mean value of 1.35kg/capita/day. The waste compositions in the different SIDS regions were almost similar owing to comparable consumption patterns while these differed to a large extent with wastes generated in OECD countries. In SIDS, the major fraction of MSW comprised of organics (44%) followed by recyclables namely paper, plastics, glass and metals (total: 43%). In contrast, MSW in OECD countries consisted mainly of recyclables (43%) followed by organics (37%). This article also reviewed the other functional elements of the waste management systems in SIDS. Several shortcomings were noted in the process of waste collection, transfer and transport namely the fact of having outdated collection vehicles and narrow roads which are inaccessible. Among the waste management practices in SIDS, waste disposal via landfilling, illegal dumping and backyard burning were favoured most of the time at the expense of sustainable waste treatment technologies such as composting, anaerobic digestion and recycling. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Schooling and Labor Market Effects of Temporary Authorization: Evidence from DACA

    OpenAIRE

    Amuedo-Dorantes, Catalina; Antman, Francisca

    2016-01-01

    This paper explores the labor market and schooling effects of the Deferred Action for Childhood Arrivals (DACA) initiative, which provides work authorization to eligible immigrants along with a temporary reprieve from deportation. The analysis relies on a difference-in-differences approach that exploits the discontinuity in program rules to compare eligible individuals to ineligible, likely undocumented immigrants before and after the program went into effect. To address potential endogeneity...

  16. Effects of multi-carbohydrase and phytase on standardized ileal digestibility of amino acids and apparent metabolizable energy in canola meal fed to broiler chicks.

    Science.gov (United States)

    Gallardo, C; Dadalt, J C; Kiarie, E; Trindade Neto, M A

    2017-09-01

    Two assays were conducted to evaluate nutritive value of canola meal (CM) fed to broiler chicks without or with a multi-carbohydrase (MC) preparation (700 U α-galactosidase, 2,200 U galactomannanase, 30,000 U xylanase, and 22,000 U β-glucanase per kg of diet) and phytase (Phy, 500 FTU per kg of diet). Assay 1 determined apparent total tract digestibility (ATTD) of nutrients and metabolizable energy (AME) by the difference method. Assay 2 determined apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of amino acids by the index method. Two reference diets (RD) - an 85% corn based and a 5% casein-cornstarch diet fortified with vitamins and minerals - were made for assays 1 and 2, respectively. For each assay, the test diets were made by mixing RD and CM 7:3 wt/wt basis and fed without or with MC or Phy or combination. A total of 245 day-old male broilers (Cobb 500) was allocated to 5 treatments to give 7 replicates (7 birds/cage). The birds were fed a commercial diet from day zero to 10 followed by assay 1 fed from d 11 to 18 and assay 2 fed from d 19 to 21. Excreta samples were collected on d 15 to18, and all birds were slaughtered on d 21 for ileal digesta. There was an interaction (P  0.05) between MC and Phy on AMEn; however, MC and Phy individually improved AMEn retention. Enzymes interacted (P < 0.05) on SID of Arg, His, Leu, Met, Thr, Ala, Asp, Gln, and Gly. In this context, feeding a combination of MC and Phy resulted in higher (P < 0.05) SID of Arg, His, Met, and Thr relative to single activity or control. Both enzymes improved (P < 0.05) SID of Lys independently. The combination of carbohydrase and Phy may be an effective strategy to improve amino acid utilization in CM for poultry. © 2017 Poultry Science Association Inc.

  17. Schooling and Labor Market Effects of Temporary Authorization: Evidence from DACA.

    Science.gov (United States)

    Amuedo-Dorantes, Catalina; Antman, Francisca

    2017-01-01

    This paper explores the labor market and schooling effects of the Deferred Action for Childhood Arrivals (DACA) initiative, which provides work authorization to eligible immigrants along with a temporary reprieve from deportation. The analysis relies on a difference-in-differences approach that exploits the discontinuity in program rules to compare eligible individuals to ineligible, likely undocumented immigrants before and after the program went into effect. To address potential endogeneity concerns, we focus on youths that likely met DACA's schooling requirement when the program was announced. We find that DACA reduced the probability of school enrollment of eligible higher-educated individuals, as well as some evidence that it increased the employment likelihood of men, in particular. Together, these findings suggest that a lack of authorization may lead individuals to enroll in school when working is not a viable option. Thus, once employment restrictions are relaxed and the opportunity costs of higher-education rise, eligible individuals may reduce investments in schooling.

  18. Patient's dose assessment during sinus X-rays radiography at 'Hopital du Point G'

    International Nuclear Information System (INIS)

    Sidibe, S.; Sacko, B.Y.; Doucoure, M.; Traore, B.; Traore, I.

    2001-01-01

    Objective: To evaluate the patient's X-rays dose during head radiography for sinusitis; To precise the influence of source-image distance on the patient's dose. Material and method: From May 1997 to January 1999, 83 patients with clinical suspicious sinusitis have been included in this study. Skull radiography in 3 positions (posterior, lateral and Blondeau view) have been achieved for each patient on 24x30 centimeters size films. These radiographies were realised on a Diagnost 7 Masio Philip X-rays machine. Three TLD dosimeters were pasted against every patient target organs (thyroid, right and left eyes). The source-image distance (SID) was 100 centimeters for the first group (35 patients) and 125 centimeters for the second group (48 patients). The selected parameters (high voltage and charge) were as follows: Skull postero-anterior view: 65 to 85 kV, 80 mAs; Skull lateral view: 60 to 75 kV, 80 mAs; Blondeau view (paranasal sinuses): 90 to 95 kV, 100 mAs. Results: All the radiographies were analysed by the same radiologist who didn't know the SID. All the films were of good quality. The patient's dose in millisievert for each target organ were: Group I (SID = 100 cm): Left eye 3,2 (+ ou - 0,66); Right eye 3, 0 (+ ou - 0,82); Thyroid 0,62 (+ ou - 0,09). Group II (SID = 125 cm): Left eye 1,9 (+ ou - 0,48); Right eye 1, 86 (+ ou - 0,50); Thyroid 0,39 (+ ou - 0,08). In conclusion, the increase of SID from 100 to 125 centimeters allows patient's dose reduction by a factor of 1.6 without the alteration of the films quality, hence the reliability of the diagnosis. (author)

  19. Barriers to reducing climate enhanced disaster risks in Least Developed Country-Small Islands through anticipatory adaptation

    Directory of Open Access Journals (Sweden)

    Natasha Kuruppu

    2015-03-01

    Full Text Available Small Island Developing States (SIDS classified as Least Developed Countries (LDCs are particularly vulnerable to the projected impacts of climate change. Given their particular vulnerabilities, climate adaptation investments are being made through both national and international efforts to build the capacity of various sectors and communities to reduce climate risks and associated disasters. Despite these efforts, reducing climate risks is not free of various challenges and barriers. This paper aims to synthesise a set of critical socio-economic barriers present at various spatial scales that are specific to Least Developed Country SIDS. It also aims to identify the processes that give rise to these barriers. Drawing on theories from natural hazards, a systematic literature review method was adopted to identify and organise the set of barriers by focussing on both academic papers and grey literature. The data revealed a notable lack of studies on adaptation within African and Caribbean LDC-SIDS. In general, there was a paucity of academic as well as grey literature being produced by authors from LDC-SIDS to challenge existing discourses related to adaptation barriers. The most common barriers identified included those related to governance, technical, cognitive and cultural. Three key findings can be drawn from this study in relation to formal adaptation initiatives. Firstly, the lack of focus on the adaptive capacity needs of Local Government or Island Councils and communities was a key barrier to ensure success of adaptation interventions. Secondly, international adaptation funding modalities did little to address root causes of vulnerability or support system transformations. These funds were geared at supporting sectoral level adaptation initiatives for vulnerable natural resource sectors such as water, biodiversity and coastal zones. Thirdly, there is a need to recognise the significance of cultural knowledge and practices in shaping

  20. Barriers to reducing climate enhanced disaster risks in Least Developed Country-Small Islands through anticipatory adaptation

    Science.gov (United States)

    Kuruppu, N.; Willie, R.

    2015-12-01

    Small Island Developing States (SIDS) classified as Least Developed Countries (LDCs) are particularly vulnerable to the projected impacts of climate change. Given their particular vulnerabilities, climate adaptation investments are being made through both national and international efforts to build the capacity of various sectors and communities to reduce climate risks and associated disasters. Despite these efforts, reducing climate risks is not free of various challenges and barriers. This paper aims to synthesise a set of critical socio-economic barriers present at various spatial scales that are specific to Least Developed Country SIDS. It also aims to identify the processes that give rise to these barriers. Drawing on theories from natural hazards, a systematic literature review method was adopted to identify and organise the set of barriers by focussing both on academic papers and grey literature. The data revealed a notable lack of studies on adaptation within African and Caribbean LDC-SIDS. In general, there was a paucity of academic as well as grey literature being produced by authors from LDC-SIDS to challenge existing discourses related to adaptation barriers. The most common barriers identified included those related to governance, technical, cognitive and cultural. Three key findings can be drawn from this study in relation to formal adaptation initiatives. Firstly, the lack of focus on the adaptive capacity needs of Local Government or Island Councils and communities was a key barrier to ensuring success of adaptation interventions. Secondly, international adaptation funding modalities did little to address root causes of vulnerability or support system transformations. These funds were geared at supporting sectoral level adaptation initiatives for vulnerable natural resource sectors such as water, biodiversity and coastal zones. Thirdly, there is a need to recognise the significance of cultural knowledge and practices in shaping adaptive choices of

  1. Evaluation of in situ valine production by Bacillus subtilis in young pigs

    DEFF Research Database (Denmark)

    Nørgaard, Jan Værum; Canibe, Nuria; Assadi Soumeh, Elham

    2016-01-01

    Mutants of Bacillus subtilis can be developed to overproduce Val in vitro. It was hypothesized that addition of Bacillus subtilis mutants to pig diets can be a strategy to supply the animal with Val. The objective was to investigate the effect of Bacillus subtilis mutants on growth performance...... and blood amino acid (AA) concentrations when fed to piglets. Experiment 1 included 18 pigs (15.0±1.1 kg) fed one of three diets containing either 0.63 or 0.69 standardized ileal digestible (SID) Val : Lys, or 0.63 SID Val : Lys supplemented with a Bacillus subtilis mutant (mutant 1). Blood samples were...... obtained 0.5 h before feeding and at 1, 2, 3, 4, 5 and 6 h after feeding and analyzed for AAs. In Experiment 2, 80 piglets (9.1±1.1 kg) were fed one of four diets containing 0.63 or 0.67 SID Val : Lys, or 0.63 SID Val : Lys supplemented with another Bacillus subtilis mutant (mutant 2) or its parent wild...

  2. Cardiac muscarinic receptor overexpression in sudden infant death syndrome.

    Directory of Open Access Journals (Sweden)

    Angelo Livolsi

    Full Text Available BACKGROUND: Sudden infant death syndrome (SIDS remains the leading cause of death among infants less than 1 year of age. Disturbed expression of some neurotransmitters and their receptors has been shown in the central nervous system of SIDS victims but no biological abnormality of the peripheral vago-cardiac system has been demonstrated to date. The present study aimed to seek vago-cardiac abnormalities in SIDS victims. The cardiac level of expression of muscarinic receptors, as well as acetylcholinesterase enzyme activity were investigated. METHODOLOGY/PRINCIPAL FINDINGS: Left ventricular samples and blood samples were obtained from autopsies of SIDS and children deceased from non cardiac causes. Binding experiments performed with [(3H]NMS, a selective muscarinic ligand, in cardiac membrane preparations showed that the density of cardiac muscarinic receptors was increased as shown by a more than doubled B(max value in SIDS (n = 9 SIDS versus 8 controls. On average, the erythrocyte acetylcholinesterase enzyme activity was also significantly increased (n = 9 SIDS versus 11 controls. CONCLUSIONS: In the present study, it has been shown for the first time that cardiac muscarinic receptor overexpression is associated with SIDS. The increase of acetylcholinesterase enzyme activity appears as a possible regulatory mechanism.

  3. Sudden infant death syndrome: an unrecognized killer in developing countries

    Directory of Open Access Journals (Sweden)

    Ndu IK

    2016-02-01

    Full Text Available Ikenna Kingsley Ndu Department of Paediatrics, Enugu State University Teaching Hospital, Enugu, Nigeria Abstract: Sudden infant death syndrome (SIDS is defined as the sudden unexpected death of an infant <1 year of age, with onset of the fatal episode apparently occurring during sleep, that remains unexplained after a thorough investigation including performance of a complete autopsy and review of the circumstances of death and the clinical history. SIDS contributes to infant mortality and resulted in ~15,000 deaths globally in 2013. Most of the risk factors of SIDS are common in developing countries; yet, there has been little interest in SIDS by researchers in Africa. This review looks at the extent of the attention given to SIDS in a developing country like Nigeria, and factors responsible for the scarce data concerning this significant cause of mortality. Keywords: SIDS, mortality, Nigeria

  4. UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions

    Science.gov (United States)

    Brem, Reto; Zhang, Xiaohui; Xu, Yao-Zhong; Karran, Peter

    2015-01-01

    Photochemotherapy, the combination of a photosensitiser and ultraviolet (UV) or visible light, is an effective treatment for skin conditions including cancer. The high mutagenicity and non-selectivity of photochemotherapy regimes warrants the development of alternative approaches. We demonstrate that the thiopyrimidine nucleosides 5-bromo-4-thiodeoxyuridine (SBrdU) and 5-iodo-4-thiodeoxyuridine (SIdU) are incorporated into the DNA of cultured human and mouse cells where they synergistically sensitise killing by low doses of UVA radiation. The DNA halothiopyrimidine/UVA combinations induce DNA interstrand crosslinks, DNA-protein crosslinks, DNA strand breaks, nucleobase damage and lesions that resemble UV-induced pyrimidine(6-4)pyrimidone photoproducts. These are potentially lethal DNA lesions and cells defective in their repair are hypersensitive to killing by SBrdU/UVA and SIdU/UVA. DNA SIdU and SBrdU generate lethal DNA photodamage by partially distinct mechanisms that reflect the different photolabilities of their C–I and C–Br bonds. Although singlet oxygen is involved in photolesion formation, DNA SBrdU and SIdU photoactivation does not detectably increase DNA 8-oxoguanine levels. The absence of significant collateral damage to normal guanine suggests that UVA activation of DNA SIdU or SBrdU might offer a strategy to target hyperproliferative skin conditions that avoids the extensive formation of a known mutagenic DNA lesion. PMID:25747491

  5. Listeriosis Phytotherapy: A Review Study on the Effectiveness of Iranian Medicinal Plants in Treatment of Listeriosis.

    Science.gov (United States)

    Rafieian-Kopaei, Mahmoud; Saki, Kourosh; Bahmani, Mahmoud; Ghafourian, Sobhan; Sadeghifard, Nourkhoda; Taherikalani, Morovat

    2015-12-17

    Listeria monocytogenes can be found in many processed foods, raw milk, dairy products, meat and meat products such as sausages, beef and fish products, seafoods, eggs, fruits, and vegetables such as radish and cabbage. This article is a review study on the Iranian medicinal plants applied for treatment of listeriosis. Information of this review article was obtained by searching various key words such as Listeria monocytogenes, medicinal plants, plant extracts and essential oils among scientific articles published in databases of Google scholar, ISI Web of Knowledge, PubMed, Scopus, SID and Magiran. Thyme, German chamomile, great chamomile, yarrow, onion, oregano, nutmeg, sage, sagebrush, hyssop, rosemary, St John's wort, safflower, ajowan, cumin, peppermint, shallot, anise, and parsnip are known antilisteriosis medicinal plants. Bioactive phytochemicals, antioxidants and monoterpenes, sesquiterpene, coumarin, flavonoids, tannins, saponins, alkaloids, and terpenoids are the main ingredients of antilisteriosis medicinal plants. © The Author(s) 2015.

  6. The Effect of Prenatal Home Visiting for Adolescent Mothers on Maternal and Neonatal Outcomes: A Systematic Review and Meta-Analysis

    OpenAIRE

    Taherh Hadian; Mojgan Mirghafourvand; Sakineh Mohammad-Alizadeh Charandabi; Solmaz Ghanbari; Jila Nahaeii; Shahla Meedya

    2018-01-01

    Background: Adolescence pregnancy is high risk both for mother and child. This systematic review aimed to determine the effect of home visiting on maternal and neonatal outcomes in adolescent mothers.Materials and Methods: This systematic review was performed by searching English databases including Cochran library, PubMed, Google scholar, Scopus, web of science, Embase, Ovid and Persian databases including SID, Magiran, and Barakat Knowledge Network System without time limitation. The search...

  7. A "Wear and Tear" Hypothesis to Explain Sudden Infant Death Syndrome.

    Science.gov (United States)

    Elhaik, Eran

    2016-01-01

    Sudden infant death syndrome (SIDS) is the leading cause of death among USA infants under 1 year of age accounting for ~2,700 deaths per year. Although formally SIDS dates back at least 2,000 years and was even mentioned in the Hebrew Bible (Kings 3:19), its etiology remains unexplained prompting the CDC to initiate a sudden unexpected infant death case registry in 2010. Due to their total dependence, the ability of the infant to allostatically regulate stressors and stress responses shaped by genetic and environmental factors is severely constrained. We propose that SIDS is the result of cumulative painful, stressful, or traumatic exposures that begin in utero and tax neonatal regulatory systems incompatible with allostasis. We also identify several putative biochemical mechanisms involved in SIDS. We argue that the important characteristics of SIDS, namely male predominance (60:40), the significantly different SIDS rate among USA Hispanics (80% lower) compared to whites, 50% of cases occurring between 7.6 and 17.6 weeks after birth with only 10% after 24.7 weeks, and seasonal variation with most cases occurring during winter, are all associated with common environmental stressors, such as neonatal circumcision and seasonal illnesses. We predict that neonatal circumcision is associated with hypersensitivity to pain and decreased heart rate variability, which increase the risk for SIDS. We also predict that neonatal male circumcision will account for the SIDS gender bias and that groups that practice high male circumcision rates, such as USA whites, will have higher SIDS rates compared to groups with lower circumcision rates. SIDS rates will also be higher in USA states where Medicaid covers circumcision and lower among people that do not practice neonatal circumcision and/or cannot afford to pay for circumcision. We last predict that winter-born premature infants who are circumcised will be at higher risk of SIDS compared to infants who experienced fewer

  8. Current status of solid waste management in small island developing states: A review

    International Nuclear Information System (INIS)

    Mohee, Romeela; Mauthoor, Sumayya; Bundhoo, Zumar M.A.; Somaroo, Geeta; Soobhany, Nuhaa; Gunasee, Sanjana

    2015-01-01

    Highlights: • Waste management is a matter of great concern for small island developing states. • On average, waste generation rate in these islands amounts to 1.29 kg/capita/day. • Illegal dumping and landfilling prevail in most small island developing states. • Sustainable waste management practices, previously absent, are now emerging. • However, many challenges still hinder the implementation of these practices. - Abstract: This article reviews the current status of waste management in Small Island Developing States (SIDS) and the challenges that are faced in solid waste management. The waste generation rates of SIDS were compared within the three geographic regions namely Caribbean SIDS, Pacific SIDS and Atlantic, Indian Ocean, Mediterranean and South China (AIMS) SIDS and with countries of the Organisation for Economic Co-Operation and Development (OECD). Only Pacific SIDS had a waste generation rate less than 1 kg/capita/day. The waste generation rates for the three SIDS regions averaged 1.29 kg/capita/day while that for OECD countries was at a mean value of 1.35 kg/capita/day. The waste compositions in the different SIDS regions were almost similar owing to comparable consumption patterns while these differed to a large extent with wastes generated in OECD countries. In SIDS, the major fraction of MSW comprised of organics (44%) followed by recyclables namely paper, plastics, glass and metals (total: 43%). In contrast, MSW in OECD countries consisted mainly of recyclables (43%) followed by organics (37%). This article also reviewed the other functional elements of the waste management systems in SIDS. Several shortcomings were noted in the process of waste collection, transfer and transport namely the fact of having outdated collection vehicles and narrow roads which are inaccessible. Among the waste management practices in SIDS, waste disposal via landfilling, illegal dumping and backyard burning were favoured most of the time at the expense of

  9. Current status of solid waste management in small island developing states: A review

    Energy Technology Data Exchange (ETDEWEB)

    Mohee, Romeela [University of Mauritius, Réduit (Mauritius); Mauthoor, Sumayya, E-mail: sumayya.mauthoor@umail.uom.ac.mu [Department of Chemical & Environmental Engineering, University of Mauritius, Réduit (Mauritius); Bundhoo, Zumar M.A.; Somaroo, Geeta; Soobhany, Nuhaa; Gunasee, Sanjana [Department of Chemical & Environmental Engineering, University of Mauritius, Réduit (Mauritius)

    2015-09-15

    Highlights: • Waste management is a matter of great concern for small island developing states. • On average, waste generation rate in these islands amounts to 1.29 kg/capita/day. • Illegal dumping and landfilling prevail in most small island developing states. • Sustainable waste management practices, previously absent, are now emerging. • However, many challenges still hinder the implementation of these practices. - Abstract: This article reviews the current status of waste management in Small Island Developing States (SIDS) and the challenges that are faced in solid waste management. The waste generation rates of SIDS were compared within the three geographic regions namely Caribbean SIDS, Pacific SIDS and Atlantic, Indian Ocean, Mediterranean and South China (AIMS) SIDS and with countries of the Organisation for Economic Co-Operation and Development (OECD). Only Pacific SIDS had a waste generation rate less than 1 kg/capita/day. The waste generation rates for the three SIDS regions averaged 1.29 kg/capita/day while that for OECD countries was at a mean value of 1.35 kg/capita/day. The waste compositions in the different SIDS regions were almost similar owing to comparable consumption patterns while these differed to a large extent with wastes generated in OECD countries. In SIDS, the major fraction of MSW comprised of organics (44%) followed by recyclables namely paper, plastics, glass and metals (total: 43%). In contrast, MSW in OECD countries consisted mainly of recyclables (43%) followed by organics (37%). This article also reviewed the other functional elements of the waste management systems in SIDS. Several shortcomings were noted in the process of waste collection, transfer and transport namely the fact of having outdated collection vehicles and narrow roads which are inaccessible. Among the waste management practices in SIDS, waste disposal via landfilling, illegal dumping and backyard burning were favoured most of the time at the expense of

  10. Effect of Bacillus subtilis and Bacillus licheniformis supplementation in diets with low- and high-protein content on ileal crude protein and amino acid digestibility and intestinal microbiota composition of growing pigs.

    Science.gov (United States)

    Kaewtapee, Chanwit; Burbach, Katharina; Tomforde, Georgina; Hartinger, Thomas; Camarinha-Silva, Amélia; Heinritz, Sonja; Seifert, Jana; Wiltafsky, Markus; Mosenthin, Rainer; Rosenfelder-Kuon, Pia

    2017-01-01

    Bacillus spp. seem to be an alternative to antimicrobial growth promoters for improving animals' health and performance. However, there is little information on the effect of Bacillus spp. in combination with different dietary crude protein (CP) levels on the ileal digestibility and microbiota composition. Therefore, the objective of this study was to determine the effect of Bacillus spp. supplementation to low- (LP) and high-protein diets (HP) on ileal CP and amino acid (AA) digestibility and intestinal microbiota composition. Eight ileally cannulated pigs with an initial body weight of 28.5 kg were randomly allocated to a row-column design with 8 pigs and 3 periods of 16 d each. The assay diets were based on wheat-barley-soybean meal with two protein levels: LP (14% CP, as-fed) and HP diet (18% CP, as-fed). The LP and HP diets were supplemented with or without Bacillus spp. at a level of 0.04% (as-fed). The apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of CP and AA was determined. Bacterial community composition from ileal digesta was analyzed by Illumina amplicon sequencing and quantitative real-time PCR. Data were analyzed as a 2 × 2 factorial design using the GLIMMIX procedures of SAS. The supplementation with Bacillus spp. did not affect both AID and SID of CP and AA in growing pigs. Moreover, there was no difference in AID of CP and AA between HP and LP diets, but SID of cystine, glutamic acid, glycine, and proline was lower ( P  digestibility, whereas LP diet may reduce the flow of undigested protein to the large intestine of pigs.

  11. [Sexual intercourse debut and associated factors in Mexican students aged 14-19 years in public schools].

    Science.gov (United States)

    Rivera-Rivera, Leonor; Leyva-López, Ahidée; García-Guerra, Armando; de Castro, Filipa; González-Hernández, Dolores; de Los Santos, Lilia Margarita

    2016-01-01

    To estimate the mean age of sexual intercourse debut (SID) and associated family and individual factors in 14-19-year-olds of both sexes in the 32 states of Mexico in 2007. A cross-sectional study was conducted of a representative sample of 9,893 students aged between 14 and 19 years old. The data were collected through a self-administered, anonymous and voluntary questionnaire. Logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (95%CI) by category: no SID, SID at 10-15 years and SID at 16-19 years. The national mean age of SID was 16 years, being 15 years for boys (95%CI: 15.88-16.11) and 16 years for girls (95%CI: 15.26-15.42). Factors associated with SID in boys were disadvantaged socioeconomic level (OR=0.66; 95%CI: 0.46-0.94), living with parents (OR=0.65; 95%CI: 0.56-0.75), less offensive communication between parents and boys/girls (OR=0.66; 95%CI: 0.57-0.77), and high social self-esteem (OR=1.68; 95%CI: 1.35-1.77). Factors associated with SID in girls were traditional gender beliefs (OR=0.49; 95%CI: 0.32-0.74), high depressive symptoms (OR=1.88; 95%CI: 1.19-2.99), and high family self-esteem (OR= 0.50; 95%CI: 0.38-0.65). In Mexico, SID occurred early in boys. In addition, the findings of this study show that in Mexico, the age of SID and associated factors differ in boys and girls. The age of SID is strongly influenced by gender and cultural beliefs. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  12. Endogenous salicylic acid is required for promoting cadmium tolerance of Arabidopsis by modulating glutathione metabolisms

    International Nuclear Information System (INIS)

    Guo, Bin; Liu, Chen; Li, Hua; Yi, Keke; Ding, Nengfei; Li, Ningyu; Lin, Yicheng; Fu, Qinglin

    2016-01-01

    Highlights: • The role of endogenous SA in mediating Cd tolerance was explored using sid2 mutants. • Cd stress induces SA accumulation in a SID2 dependent way. • Depletion of SA causes negative effects on Cd tolerance. • Endogenous SA is required for promoting Cd tolerance by modulating GSH metabolism. • Possible mode of SA signaling through GR/GSH pathway under Cd toxicity was discussed. - Abstract: A few studies with NahG transgenic lines of Arabidopsis show that depletion of SA enhances cadmium (Cd) tolerance. However, it remains some uncertainties that the defence signaling may be a result of catechol accumulation in NahG transgenic lines but not SA deficiency. Here, we conducted a set of hydroponic assays with another SA-deficient mutant sid2 to examine the endogenous roles of SA in Cd tolerance, especially focusing on the glutathione (GSH) cycling. Our results showed that reduced SA resulted in negative effects on Cd tolerance, including decreased Fe uptake and chlorophyll concentration, aggravation of oxidative damage and growth inhibition. Cd exposure significantly increased SA concentration in wild-type leaves, but did not affect it in sid2 mutants. Depletion of SA did not disturb the Cd uptake in either roots or shoots. The reduced Cd tolerance in sid2 mutants is due to the lowered GSH status, which is associated with the decreased expression of serine acetyltransferase along with a decline in contents of non-protein thiols, phytochelatins, and the lowered transcription and activities of glutathione reductase1 (GR1) which reduced GSH regeneration. Finally, the possible mode of SA signaling through the GR/GSH pathway during Cd exposure is discussed.

  13. Endogenous salicylic acid is required for promoting cadmium tolerance of Arabidopsis by modulating glutathione metabolisms

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Bin, E-mail: ndgb@163.com [Institute of Environment, Resource, Soil and Fertilizer, Zhejiang Academy of Agricultural Sciences, Geological Research Center For Agricultural Applications, China Geological Survey, Hangzhou (China); Liu, Chen; Li, Hua [Institute of Environment, Resource, Soil and Fertilizer, Zhejiang Academy of Agricultural Sciences, Geological Research Center For Agricultural Applications, China Geological Survey, Hangzhou (China); Yi, Keke [Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou (China); Ding, Nengfei; Li, Ningyu; Lin, Yicheng [Institute of Environment, Resource, Soil and Fertilizer, Zhejiang Academy of Agricultural Sciences, Geological Research Center For Agricultural Applications, China Geological Survey, Hangzhou (China); Fu, Qinglin, E-mail: fuql161@yahoo.com.cn [Institute of Environment, Resource, Soil and Fertilizer, Zhejiang Academy of Agricultural Sciences, Geological Research Center For Agricultural Applications, China Geological Survey, Hangzhou (China)

    2016-10-05

    Highlights: • The role of endogenous SA in mediating Cd tolerance was explored using sid2 mutants. • Cd stress induces SA accumulation in a SID2 dependent way. • Depletion of SA causes negative effects on Cd tolerance. • Endogenous SA is required for promoting Cd tolerance by modulating GSH metabolism. • Possible mode of SA signaling through GR/GSH pathway under Cd toxicity was discussed. - Abstract: A few studies with NahG transgenic lines of Arabidopsis show that depletion of SA enhances cadmium (Cd) tolerance. However, it remains some uncertainties that the defence signaling may be a result of catechol accumulation in NahG transgenic lines but not SA deficiency. Here, we conducted a set of hydroponic assays with another SA-deficient mutant sid2 to examine the endogenous roles of SA in Cd tolerance, especially focusing on the glutathione (GSH) cycling. Our results showed that reduced SA resulted in negative effects on Cd tolerance, including decreased Fe uptake and chlorophyll concentration, aggravation of oxidative damage and growth inhibition. Cd exposure significantly increased SA concentration in wild-type leaves, but did not affect it in sid2 mutants. Depletion of SA did not disturb the Cd uptake in either roots or shoots. The reduced Cd tolerance in sid2 mutants is due to the lowered GSH status, which is associated with the decreased expression of serine acetyltransferase along with a decline in contents of non-protein thiols, phytochelatins, and the lowered transcription and activities of glutathione reductase1 (GR1) which reduced GSH regeneration. Finally, the possible mode of SA signaling through the GR/GSH pathway during Cd exposure is discussed.

  14. Quantitative accuracy of the simplified strong ion equation to predict serum pH in dogs.

    Science.gov (United States)

    Cave, N J; Koo, S T

    2015-01-01

    Electrochemical approach to the assessment of acid-base states should provide a better mechanistic explanation of the metabolic component than methods that consider only pH and carbon dioxide. Simplified strong ion equation (SSIE), using published dog-specific values, would predict the measured serum pH of diseased dogs. Ten dogs, hospitalized for various reasons. Prospective study of a convenience sample of a consecutive series of dogs admitted to the Massey University Veterinary Teaching Hospital (MUVTH), from which serum biochemistry and blood gas analyses were performed at the same time. Serum pH was calculated (Hcal+) using the SSIE, and published values for the concentration and dissociation constant for the nonvolatile weak acids (Atot and Ka ), and subsequently Hcal+ was compared with the dog's actual pH (Hmeasured+). To determine the source of discordance between Hcal+ and Hmeasured+, the calculations were repeated using a series of substituted values for Atot and Ka . The Hcal+ did not approximate the Hmeasured+ for any dog (P = 0.499, r(2) = 0.068), and was consistently more basic. Substituted values Atot and Ka did not significantly improve the accuracy (r(2) = 0.169 to <0.001). Substituting the effective SID (Atot-[HCO3-]) produced a strong association between Hcal+ and Hmeasured+ (r(2) = 0.977). Using the simplified strong ion equation and the published values for Atot and Ka does not appear to provide a quantitative explanation for the acid-base status of dogs. Efficacy of substituting the effective SID in the simplified strong ion equation suggests the error lies in calculating the SID. Copyright © 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  15. Efficiency of utilizing ileal digestible lysine and threonine for whole body protein deposition in growing pigs is reduced when dietary casein is replaced by wheat shorts.

    Science.gov (United States)

    Libao-Mercado, A J; Leeson, S; Langer, S; Marty, B J; de Lange, C F M

    2006-06-01

    To determine the effect of dietary inclusion level of wheat shorts (WS; a high nonstarch poly-saccharide-containing feed ingredient) and casein (CS; a control) on the efficiency of utilizing ileal digestible Lys (kLys) and Thr (kThr) for whole body protein deposition (PD) in the growing pig, 2 separate N-balance studies were conducted with either Lys or Thr as first-limiting AA in cornstarch-based diets. For the Lys study, a basal diet (L-basal) was formulated to contain 0.24 g of standardized ileal digestible (SID) Lys per MJ of DE, to which 0.095 or 0.19 g of SID Lys per MJ of DE were added using either CS (L-CS2 or L-CS3, respectively) or WS (L-WS2 or L-WS3, respectively). A sixth diet was evaluated that was similar to L-CS3 but to which 6% pectin (L-pectin) was added as a source of soluble nonstarch polysaccharides. For the Thr study, the basal diet (T-basal) was formulated to contain 0.14 g of SID Thr per MJ of DE, to which 0.055 or 0.11 g of SID Thr per MJ of DE were added from CS (T-CS2 or T-CS3, respectively) or from WS (T-WS2 and T-WS3, respectively). A sixth diet was evaluated that was similar to T-CS3 but to which 6% pectin was added (T-pectin). Increasing SID Lys intake from CS did not influence kLys for PD (P > 0.10), whereas increasing SID Lys intake from WS reduced kLys for PD (P = 0.001; 89 vs. 79%). Inclusion of 6% pectin had no effect on kLys for PD (P > 0.10). Increasing SID Thr intake from CS also did not influence kThr for PD (P > 0.10), whereas kThr for PD was reduced at the greatest dietary inclusion level of WS (P 0.10). The inefficiency of utilizing ileal digestible Lys intake for PD may be attributed to nonreactive Lys in WS. The negative impact of including high levels of WS in the diet of pigs on kThr seems to be associated with fiber content of WS; it was not related to increased endogenous ileal AA losses at the distal ileum. The impact of dietary AA source on the use of ileal digestible Lys and Thr for PD, or other body functions, is

  16. 75 FR 63480 - Delegation of Authorities

    Science.gov (United States)

    2010-10-15

    ... exercise of the authorities delegated herein prior to the effective date of this delegation. This delegation of authorities granted herein is effective immediately. Authority: 44 U.S.C. 3101. Dated... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Centers for Medicare & Medicaid...

  17. 20 CFR 726.103 - Application for authority to self-insure; effect of regulations contained in this part.

    Science.gov (United States)

    2010-04-01

    ... § 726.103 Application for authority to self-insure; effect of regulations contained in this part. As... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Application for authority to self-insure; effect of regulations contained in this part. 726.103 Section 726.103 Employees' Benefits EMPLOYMENT...

  18. 76 FR 22396 - Delegation of Authority

    Science.gov (United States)

    2011-04-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Delegation of Authority Notice is... Department's policy on regulations and the existing delegation of authority to approve and issue regulations... effective date of this delegation. This delegation is effective upon signature. (Authority: Section 6 of the...

  19. Maternal smoking and alcohol consumption during pregnancy as risk factors for sudden infant death.

    LENUS (Irish Health Repository)

    McDonnell-Naughton, M

    2012-04-01

    A population based case control study was conducted to examine alcohol consumption and maternal smoking during pregnancy and the risk of SIDS in an Irish population. Each SIDS case (n = 287) was compared with control infants (n = 832) matched for date and place of birth for infants born from 1994 to 2001. Conditional logistic regression was used to investigate differences between Cases and Controls establishing Odds Ratio\\'s (OR) and 95% Confidence Intervals (CI). Mothers who smoked were 3 times more likely to have a SIDS Case, and a dose response effect was apparent, with mothers smoking 1-10 cigarettes\\/day OR 2.93 (CI 1.50-5.71), and those smoking > 10 cigarettes\\/day OR 4.36 (CI 2.50-7.61). More Case mothers consumed alcohol during pregnancy than Control mothers and, within drinkers, the amount of alcohol consumed was also greater (p < 0.05). A dose response with frequency of drinking was apparent. The adjusted odds ratio for those consuming alcohol in all three trimesters was 3.59 (CI:1.40-9.20). Both of these risk factors are modifiable and need to be incorporated into antenatal education from a SIDS point of view.

  20. 76 FR 25355 - Delegation of Authority

    Science.gov (United States)

    2011-05-04

    ... subordinates, which involve the exercise of this authority prior to the effective date of this delegation. This delegation is effective upon date of signature. Authority: 44 U.S.C. 3101. Dated: April 22, 2011. Kathleen... DEPARTMENT OF HEALTH AND HUMAN SERVICES (HHS) Office of the Secretary Delegation of Authority...

  1. Authoring Effective Demonstrations

    National Research Council Canada - National Science Library

    Fu, Dan; Jensen, Randy; Salas, Eduardo; Rosen, Michael A; Ramachandran, Sowmya; Upshaw, Christin L; Hinkelman, Elizabeth; Lampton, Don

    2007-01-01

    ... or human role-players for each training event. We report our ongoing efforts to (1) research the nature and purpose of demonstration, articulating guidelines for effective demonstration within a training context, and (2...

  2. Effect of benazepril and pimobendan on serum angiotensin-converting enzyme activity in dogs.

    Science.gov (United States)

    King, J N; Christinaz, C; Strehlau, G; Hornfeld, J

    2018-06-01

    To support their combined use, the objective of the study was to evaluate the effects of benazepril and pimobendan on serum angiotensin-converting enzyme (ACE) activity in dogs. A total of 48 healthy beagle dogs were randomized into four groups (n = 12 per group) in a parallel-group design study: A (control, placebo twice daily (BID)); B (0.5-1.0 mg/kg benazepril once daily (SID) in the morning, placebo in the evening); C (0.25-0.5 mg/kg benazepril BID); D (0.25-0.5 mg/kg benazepril and 0.125-0.25 mg/kg pimobendan, both BID). The test items were administered orally for 15 days. Serum ACE activity was measured on days 1 and 15. Groups B, C and D had significantly lower average serum ACE activity compared to baseline and to the control group, on both days 1 and 15. There were no significant differences in average ACE activity between groups B, C and D. Noninferiority of group C to B was demonstrated. In conclusion, 0.25-0.5 mg/kg benazepril administered BID produced noninferior inhibition of serum ACE activity compared to 0.5-1.0 mg/kg benazepril dosed SID. Pimobendan had no significant effect on benazepril's action on serum ACE activity. The results support the use of benazepril BID in dogs and in combination with pimobendan. © 2018 John Wiley & Sons Ltd.

  3. Effects of dietary cellulose levels on the estimation of endogenous amino acid losses and amino acid digestibility for growing pigs

    Directory of Open Access Journals (Sweden)

    Zhengqun Liu

    2016-06-01

    Full Text Available Two experiments were conducted to investigate the effects of dietary cellulose levels on the determination of the ileal endogenous losses (IEL of amino acids (AA, apparent ileal digestibility (AID and standardized ileal digestibility (SID of AA in corn-soybean meal diets for growing pigs. In the first experiment, 28 pigs (BW, 45.1 ± 2.0 kg that were fitted with simple T-cannulas at the distal ileum were fed 4 nitrogen-free diets consisting of 4 dietary cellulose levels (0, 3%, 6% and 9% in a randomized complete block design. In the second experiment, 28 pigs (BW, 45.6 ± 2.0 kg fitted with simple T-cannulas at the distal ileum were fed 4 corn-soybean meal diets consisting of 4 dietary cellulose levels (0, 3%, 6% and 9% in a randomized complete block design. There were 7 replicates per diet with 1 pig as a replicate in each treatment. Both experiments consisted of a 7-d adjustment period and a 2-d ileal digesta collection period on d 8 and 9. Chromic oxide was used as an indigestible marker to calculate IEL and digestibility of AA. The results showed that the IEL of AA for growing pigs was not influenced by dietary cellulose supplementation (P > 0.05. The AID of Thr, Ser, Glu, Cys, Ile, Tyr, Phe, Lys and His decreased with increasing cellulose supplementation levels for pigs fed corn-soybean meal diets (P < 0.05. The SID of Thr, Ser, Cys, Val, Ile, Tyr, Phe, Lys and His decreased with increasing cellulose supplementation levels in corn-soybean meal diets (P < 0.05. In summary, dietary cellulose levels had no effect on the estimation of IEL of AA for growing pigs. The AID and SID of most AA in corn-soybean meal diets decreased with increasing levels of dietary cellulose supplementation.

  4. Worldsid small female side impact dummy specifications and prototype evaluation

    NARCIS (Netherlands)

    Been, B.W.; Meijer, R.; Bermond, F.; Bortenschlager, K.; Hynd, D.; Martinez, L.; Ferichola, G.

    2007-01-01

    The WorldSID program was set up to develop a new, worldwide acceptable, advanced technology, side impact crash test dummy for improved assessment of injury risk to car occupants in lateral collisions. Following the release of the mid-sized male WorldSID, the development of the small female WorldSID

  5. Sudden infant death syndrome and the genetics of inflammation

    Directory of Open Access Journals (Sweden)

    Linda eFerrante

    2015-02-01

    Full Text Available Several studies report signs of slight infection prior to death in cases of sudden infant death syndrome (SIDS. Based on this, a hypothesis of an altered immunological homeostasis has been postulated. The cytokines are important cellular mediators that are crucial for infant health by regulating cell activity during the inflammatory process. The pro-inflammatory cytokines favor inflammation; the most important of these are IL-1α, IL-1β, IL-6, IL-8, IL-12, IL-18, TNF-α and IFN-γ. These cytokines are controlled by the anti-inflammatory cytokines. This is accomplished by reducing the pro-inflammatory cytokine production, and thus counteracts their biological effect. The major anti-inflammatory cytokines are interleukin 1 receptor antagonist (IL-1ra, IL-4, IL-10, IL-11, and IL-13. The last decade there has been focus on genetic studies within genes that are important for the immune system, for SIDS with a special interest of the genes encoding the cytokines. This is because the cytokine genes are considered to be the genes most likely to explain the vulnerability to infection, and several studies have investigated these genes in an attempt to uncover associations between SIDS and different genetic variants. So far the genes encoding IL-1, IL-6, IL-10 and TNF-α are the most investigated within SIDS research, and several studies indicates associations between specific variants of these genes and SIDS. Taken together this may indicate that in at least a subset of SIDS predisposing genetic variants of the immune genes are involved. However, the immune system and the cytokine network are complex, and more studies are needed in order to better understand the interplay between different genetic variations and how this may contribute to an unfavorable immunological response.

  6. Author Details

    African Journals Online (AJOL)

    , Incubators and the Effects of a Spray-Disinfectant - A Quarterly Ammonium Compound Abstract. ISSN: 1116-1043. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  7. Cine-oeso-gastro-scintigraphy (COGS) and gastro-oesophageal reflux (GOR): a 15-year experience; Cine-oesogastroscintigraphie et reflux gastro-oesophagien de l`enfant: 15 ans d`experience

    Energy Technology Data Exchange (ETDEWEB)

    Guillet, J.; Role, C.; Joussein, M.

    1996-12-31

    Eight thousand COGS were performed, searching for, quantifying and visualizing GOR, and possibly associated oesophageal dismotility or gastric emptying disorders in neonates (15 %), infants (33 %), children 1-4 (20%), 4-8 (20%) and 8-16 years old (14%). Indications were medical or surgical, to diagnoses, assess or follow up GOR with or without treatment. GOR was discovered in 65 % of the cases. A respiratory contamination by GOR aspiration was visualized in 4 % of patients with recurrent respiratory diseases, or near miss from sudden infant death syndrome (SIDS). Pathological patterns of gastric emptying in SIDS are emphasized. Oesophageal motility dysfunctions, primary or related to oesophagitis, are visualized and quantified by scintigraphic imaging. PH-metry and scintigraphy accuracies and their relative positions are discussed. (authors). 117 refs., 8 figs., 5 tabs.

  8. Scenario development and evaluation for the NPP Krsko revised decommissioning program

    International Nuclear Information System (INIS)

    Levanat, I.; Lokner, V.; Subasic, D.

    2004-01-01

    adopted. The procedure relies on an integrated scenario timetable, in which decisive DP activities are charted side by side, together with the schedule of their annual expenses which will be used as input for the subsequent discounting and cash flow calculations. This finally led to three groups of scenarios consistent with the boundary conditions: (1) SID-96 scenarios (the required re-evaluation of the original SID strategy); (2) SID-15 scenarios in which all DP activities would be completed in 15 years or less; and (3) SID scenarios with dry storage of SF. The cash flow calculations demonstrated that the SF dry storage scenarios have the lowest discounted costs. Also, they provide the greatest confidence in timely realization of the SF disposal or export plans. In addition to a pair of 30-year dry storage scenarios (with the SF disposal or export), an option of 45-year SF storage was also introduced. Actually, the SID-30 and SID-45 scenarios can be viewed only as limiting cases of an entire range of the intermediate SF dry storage options. Therefore, the decision on the DP funding can reasonably be based upon the SID-45 cost estimates, possibly rounded upwards to an amount which would encompass some of the shorter variants too.(author)

  9. Serotonin Metabolites in the Cerebrospinal Fluid in the Sudden Infant Death Syndrome: In Search of a Biomarker of Risk

    Science.gov (United States)

    Rognum, Ingvar J.; Tran, Hoa; Haas, Elisabeth A.; Hyland, Keith; Paterson, David S.; Haynes, Robin L.; Broadbelt, Kevin G.; Harty, Brian J.; Mena, Othon; Krous, Henry F.; Kinney, Hannah C.

    2015-01-01

    Clinical biomarkers are urgently needed in the sudden infant death syndrome (SIDS) to identify living infants at risk because it because it occurs without occurs without clinical warning. Previously, we reported multiple serotonergic (5-HT) abnormalities in nuclei of the medulla oblongata that help mediate protective responses to homeostatic stressors. Here we test the hypothesis that 5-HT-related measures are abnormal in the cerebrospinal fluid (CSF) of SIDS infants compared to autopsy controls, as a first step towards their assessment as diagnostic biomarkers of medullary pathology. Levels of CSF 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA), the degradative products of 5-HT and dopamine, respectively, were measured by high performance liquid chromatography in 57 SIDS and 29 non-SIDS autopsy cases. Tryptophan (Trp) and tyrosine (Tyr), the substrates of 5-HT and dopamine, respectively, were also measured. There were no significant differences in 5-HIAA, Trp, HVA, or Tyr levels between the SIDS and non-SIDS groups. These data preclude use of 5-HIAA, HVA, Trp or Tyr measurements as CSF biomarkers of 5-HT medullary pathology in infants at risk. They provide, however, important information about monoaminergic measurements in human CSF at autopsy and their developmental profile in infancy that is applicable to multiple pediatric disorders beyond SIDS. PMID:24423636

  10. Stressful life events in childhood and risk of infectious disease hospitalization.

    Science.gov (United States)

    Nielsen, Nete Munk; Hansen, Anne Vinkel; Simonsen, Jacob; Hviid, Anders

    2012-01-01

    Individuals exposed to high levels of stress might have an increased risk of infectious diseases. However, most of the previous studies have been conducted among adults. To examine the effect of childhood stress, we conducted a nationwide cohort study including all Danish children born from 1977 to 2004. Stressful life events (SFLE) included parental death, death of sibling or parental divorce. Outcome was defined as hospitalizations due to less severe (LSID) or severe infectious diseases (SID). Children were followed until the age of 15 years. The association between SFLE and risk of infections was evaluated through rate ratios (RR) comparing infectious disease incidence ratios in children with and without a history of SFLE. Overall, children exposed to SFLE were at 13% increased risk of LSID (RR = 1.13 (1.10-1.15)), but at no increased risk of SID hospitalization (RR = 1.05 (0.97-1.14)). Looking at the specific type of SFLE, parental divorce increased the risk of LSID (RR = 1.11 (1.09-1.14)) and SID hospitalization (1.11 (1.02-1.21)) by 11%, whereas no increased risk of LSID and SID hospitalization was observed following parental death. Finally, a 34% increased risk of LSID hospitalization (RR = 1.34 (1.23-1.45)) was observed following death of sibling, in contrast to no increased risk of SID hospitalization. Childhood exposure to SFLE, especially parental divorce seems to increase the risk of infectious disease hospitalization. Although we cannot determine whether our observations are the result of a biological effect of stress, adoption of unhealthy behaviours or increased likelihood of hospitalization, our findings do have public health relevance as a considerable proportion of the children today will be exposed to SFLE, the majority to parental divorce.

  11. Author Details

    African Journals Online (AJOL)

    inflammatory effects of Clerodendrum phlomidis in mice and rats. Abstract PDF. ISSN: 1997-342X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

  12. Author Details

    African Journals Online (AJOL)

    polarization effects on satellite telecommunication in some tropical location. Abstract PDF. ISSN: 1595-0611. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  13. Author Details

    African Journals Online (AJOL)

    : effects on infant and young child health and feeding practices. Abstract PDF. ISSN: 2078-6204. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

  14. 78 FR 50057 - Delegation of Authorities

    Science.gov (United States)

    2013-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Delegation of Authorities Notice... to the effective date of this delegation of authorities. Nothing in this delegation of authorities is... delegation of authorities excludes the authority to issue regulations and to submit reports to Congress...

  15. Otolaryngological aspects of sudden infant death syndrome.

    Science.gov (United States)

    Marom, Tal; Cinamon, Udi; Castellanos, Paul F; Cohen, Marta C

    2012-03-01

    Sudden infant death syndrome (SIDS) is characterized by the sudden death of an apparently otherwise healthy infant, typically during sleep, and with no obvious case after a thorough post-mortem and scene death examination. To address the problem from the otolaryngologist's perspective, describe relevant pathologies, discuss controversies and suggest preventive measures in high-risk populations. A MEDLINE search and hand search were conducted to identify reports published between 1969 and 2011 in the English language on the pathophysiology of SIDS related to the head and neck organs. Search terms included SIDS (MeSH term), SIDS and pathophysiology (text words), and SIDS and autopsy (text words). A growing number of reports suggested head and neck organs involvement in SIDS autopsies. Laryngeal, oropharyngeal, maxillofacial, otologic, cervical vascular abnormalities and infectious etiologies, were recognized and discussed. Otolaryngologists should be aware of relevant pathologies, as some are treatable, if identified early enough in infancy. A proactive risk-management approach is warranted in infants presenting with certain abnormalities reviewed here. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  16. Iron-dependent gene expression in Actinomyces oris

    Directory of Open Access Journals (Sweden)

    Matthew P. Mulé

    2015-12-01

    Results: When A. oris was grown under iron-limiting conditions, the genes encoding iron/siderophore transporters fetA and sidD showed increased expression. One of these genes (sidD was mutated, and the sidD::Km strain exhibited a 50% reduction in growth in late log and stationary phase cells in media that contained iron. This growth defect was restored when the sidD gene was provided in a complemented strain. We were able to isolate the AmdR-encoding gene in seven clinical isolates of Actinomyces. When these protein sequences were aligned to the laboratory strain, there was a high degree of sequence similarity. Conclusions: The growth of the sidD::Km mutant in iron-replete medium mirrored the growth of the wild-type strain grown in iron-limiting medium, suggesting that the sidD::Km mutant was compromised in iron uptake. The known iron regulator AmdR is well conserved in clinical isolates of A. oris. This work provides additional insight into iron metabolism in this important oral microbe.

  17. Effect of omega-3 on auditory system

    Directory of Open Access Journals (Sweden)

    Vida Rahimi

    2014-01-01

    Full Text Available Background and Aim: Omega-3 fatty acid have structural and biological roles in the body 's various systems . Numerous studies have tried to research about it. Auditory system is affected a s well. The aim of this article was to review the researches about the effect of omega-3 on auditory system.Methods: We searched Medline , Google Scholar, PubMed, Cochrane Library and SID search engines with the "auditory" and "omega-3" keywords and read textbooks about this subject between 19 70 and 20 13.Conclusion: Both excess and deficient amounts of dietary omega-3 fatty acid can cause harmful effects on fetal and infant growth and development of brain and central nervous system esspesially auditory system. It is important to determine the adequate dosage of omega-3.

  18. An Effective Health and Medical Technical Authority

    Science.gov (United States)

    Fogarty, Jennifer A.

    2009-01-01

    The NASA Governance model directed the formation of three Technical Authorities, Engineering; Safety and Mission Assurance; and Health and Medical, to ensure that risks are identified and adjudicated efficiently and transparently in concert with the spaceflight programs and projects. The Health and Medical Technical Authority (HMTA) has been implemented at the Johnson Space Center (JSC) and consists of the Chief Medical Office (CMO), the Deputy CMO, and HMTA Delegates. The JSC HMTA achieves the goals of risk identification and adjudication through the discharge of the appropriate technical expertise to human space flight programs and projects and the escalation of issues within program and technical authority boards. The JSC HMTA relies on subject matter experts (SMEs) in the Space Life Sciences Directorate at JSC as well as experts from other Centers to work crew health and performance issues at the technical level, develop requirements, oversee implementation and validation of requirements, and identify risks and non-compliances. Once a risk or potential noncompliance has been identified and reported to the programs or projects, the JSC HMTA begins to track it and closely monitor the program's or project's response. As a risk is developed or a non-compliance negotiated, positions from various levels of decision makers are sought at the program and project control boards. The HMTA may support a program or project position if it is satisfied with the decision making and vetting processes (ex. the subject matter expert voiced his/her concerns and all dissenting opinions were documented) and finds that the position both acknowledges the risk and cost of the mitigation and resolves the issue without changing NASA risk posture. The HMTA may disagree with a program or project position if the NASA risk posture has been elevated or obfuscated. If the HMTA does disagree with the program or project position, it will appeal to successively higher levels of authority so that

  19. Cigarette prices, cigarette expenditure and smoking-induced deprivation: findings from the International Tobacco Control Mexico survey.

    Science.gov (United States)

    Siahpush, Mohammad; Thrasher, James F; Yong, Hua H; Cummings, K Michael; Fong, Geoffrey T; de Miera, Belén Saenz; Borland, Ron

    2013-07-01

    Mexico implemented annual tax increases between 2009 and 2011. We examined among current smokers the association of price paid per cigarette and daily cigarette expenditure with smoking-induced deprivation (SID) and whether the association of price or expenditure with SID varies by income. We used data (n=2410) from three waves of the International Tobacco Control Mexico survey (ie, 2008, 2010, 2011) and employed logistic regression to estimate the association of price paid per cigarette and daily cigarette expenditure with the probability of SID ('In the last 6 months, have you spent money on cigarettes that you knew would be better spent on household essentials like food?'). Price paid per cigarette increased from Mex$1.24 in 2008, to Mex$1.36 in 2010, to Mex$1.64 in 2011. Daily cigarette expenditure increased from Mex$6.9, to Mex$7.6 and to Mex$8.4 in the 3 years. There was no evidence of an association between price and SID. However, higher expenditure was associated with a higher probability of SID. There was no evidence that the association of price or expenditure with SID varied by income. Tax increases in Mexico have resulted in smokers paying more and spending more for their cigarettes. Those with higher cigarette expenditure experience more SID, with no evidence that poorer smokers are more affected.

  20. Induction of short culm mutants for bread wheat by using gamma rays

    International Nuclear Information System (INIS)

    Sobieh, S.S.

    2002-01-01

    This investigation was conducted at the experimental farm of plant research department, nuclear research center, atomic energy authority, Inshas in order to select some short culm mutants from the local wheat varieties; Sid's-5, Sid's-6 and Sid's-7 after gamma irradiation. The obtained results indicated that: 1-M 4 mutants progenies retained the features of their M 3 selections. 2-Some short culm mutants exhibited high grain yield/plant as compared to their original varieties. 3-There were significant decreases in plant height varied from 21.4 to 35.4%. This reduction was due to the shorting of culm inter nods length. As well as, the reduction diameter/culm especially diameter of the inter nods/culm did not differed between original varieties and the mutants. 4-The correlation between grain yield/plant and number of spikes/plant was positive and highly significant for most mutants and the original varieties as well. Data also showed that there were positive relationship between grain yield/plant and number of grains/spike and and length of the inter nods/culm. Positive or negative association between grain yield/plant and plant height as well as diameters of inter nods/culm for mutants and original varieties were detected

  1. 77 FR 72350 - Delegation of Authorities

    Science.gov (United States)

    2012-12-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Delegation of Authorities Notice is hereby given that I... ensure that CMS' provider enrollment process continues without interruption. This delegation of authority... effective date of this delegation of authority. These authorities may be re-delegated. This delegation of...

  2. Amino acid digestibility of corn distillers dried grains with solubles, liquid condensed solubles, pulse dried thin stillage, and syrup balls fed to growing pigs.

    Science.gov (United States)

    Soares, J A; Stein, H H; Singh, V; Shurson, G S; Pettigrew, J E

    2012-04-01

    Distillers dried grains with solubles (DDGS) has low and variable AA digestibility. The variability is often attributed to damage during the heating process, and it has been suggested that the damage happens to the soluble components of DDGS such as reducing sugars. Combining solubles and grains sometimes produces syrup balls (SB); their digestibility is unknown. The objective of this experiment was to identify potential sources of poor and variable AA digestibility in DDGS. Specifically, our objective was to determine whether the problems are associated with the solubles component or with SB. The ingredients evaluated were DDGS, intact SB, ground SB, liquid condensed solubles (LCS), and pulse dried thin stillage (PDTS) obtained from the same ethanol plant. The LCS is produced by evaporation of thin stillage. Each ingredient was used as the only source of AA in an experimental diet. In a duplicate 6 × 6 Latin square design with 7-d adaptation and collection periods, the 6 treatments consisted of an N-free diet and the 5 test ingredients. Pigs had 5 d of adaptation to each diet, and on d 6 and 7 ileal digesta were collected from an ileal cannula for 8 h each day. Both SB treatments had apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of AA that were similar or greater (P < 0.05) than those of DDGS. The AID and SID values of Lys and a few other AA were similar in LCS (SID Lys: 63.1%) and DDGS (SID Lys: 61.5%), but the digestibility values of most AA in LCS were less than in DDGS (P < 0.05). The low digestibility of AA in LCS was most pronounced for Met (SID: LCS, 41.9% vs. DDGS, 82.8%). The LCS had less (P < 0.05) AID and SID of CP (SID: 67.8%) than intact SB (SID: 85.2%) and ground SB (SID: 85.9%) as well as all AA. The PDTS generally had the least AID and SID and had less (P < 0.05) CP (SID: 55.3%) and several AA, including Lys, compared with LCS. In conclusion, the presence of SB does not decrease AA digestibility of DDGS, and the LCS

  3. FORENSIC LINGUISTICS: AUTOMATIC WEB AUTHOR IDENTIFICATION

    Directory of Open Access Journals (Sweden)

    A. A. Vorobeva

    2016-03-01

    Full Text Available Internet is anonymous, this allows posting under a false name, on behalf of others or simply anonymous. Thus, individuals, criminal or terrorist organizations can use Internet for criminal purposes; they hide their identity to avoid the prosecuting. Existing approaches and algorithms for author identification of web-posts on Russian language are not effective. The development of proven methods, technics and tools for author identification is extremely important and challenging task. In this work the algorithm and software for authorship identification of web-posts was developed. During the study the effectiveness of several classification and feature selection algorithms were tested. The algorithm includes some important steps: 1 Feature extraction; 2 Features discretization; 3 Feature selection with the most effective Relief-f algorithm (to find the best feature set with the most discriminating power for each set of candidate authors and maximize accuracy of author identification; 4 Author identification on model based on Random Forest algorithm. Random Forest and Relief-f algorithms are used to identify the author of a short text on Russian language for the first time. The important step of author attribution is data preprocessing - discretization of continuous features; earlier it was not applied to improve the efficiency of author identification. The software outputs top q authors with maximum probabilities of authorship. This approach is helpful for manual analysis in forensic linguistics, when developed tool is used to narrow the set of candidate authors. For experiments on 10 candidate authors, real author appeared in to top 3 in 90.02% cases, on first place real author appeared in 70.5% of cases.

  4. Author Details

    African Journals Online (AJOL)

    NIMENIBO-UADIA, Rachel. Vol 15, No 1 (2003) - Articles Effect of aqueous extract of Canavalia ensiformis seeds on hyperlipidaemia and hyperketonaemia in alloxan-induced diabetic rats. Abstract PDF. ISSN: 0795-8080. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  5. Author Details

    African Journals Online (AJOL)

    Ahmed, Hanaa H. Vol 10, No 1 (2001) - Articles POTENTIATION OF THE PROTECTIVE EFFECTS OF MELATONIN AND CELL PROTECT IN EHRLICH ASCITES CARINOMA BEARING MICE Abstract. ISSN: 1110-5593. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

  6. Author Details

    African Journals Online (AJOL)

    Mannaa, Fathia. Vol 10, No 1 (2001) - Articles POTENTIATION OF THE PROTECTIVE EFFECTS OF MELATONIN AND CELL PROTECT IN EHRLICH ASCITES CARINOMA BEARING MICE Abstract. ISSN: 1110-5593. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

  7. Author Details

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    Singh, Shivangna. Vol 11, No 2 (2016) - Articles Metabolic effects of Olanzapine versus Iloperidone: A 24 weeks randomized, prospective, interventional study. Abstract PDF. ISSN: 1694-0423. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  8. Author Details

    African Journals Online (AJOL)

    Awofodu, DB. Vol 9, No 1 (2011) - Articles Effects of constructivist teaching strategies and traditional lecture method on students' learning outcomes in Nigeria's integrated science education. Abstract PDF. ISSN: 2508-1128. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  9. Author Details

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    Sogomo, KC. Vol 16, No 1 (2011) - Articles Effects of Using the Dimensions of Creativity in Teaching Mathematics on Students' Achievement and Perception of Classroom Learning Environment Abstract. ISSN: 1118-5570. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  10. Three predictions on July 2012 Federal Elections in Mexico based on past regularities

    OpenAIRE

    Hernández-Saldaña, H.

    2012-01-01

    Electoral systems are subject of study for physicist and mathematicians in last years given place to a new area: sociophysics. Based on previous works of the author on the Mexican electoral processes in the new millennium, he found three characteristics appearing along the 2000 and 2006 preliminary dataset offered by the electoral authorities, named PREP: I) Error distributions are not Gaussian or Lorentzian, they are characterized for power laws at the center and asymmetric lobes at each sid...

  11. Author Details

    African Journals Online (AJOL)

    Agu, NN. Vol 8 (2010) - Articles Effects of mathematical game and instructional analogy as advance organizers on students' achievement in secondary school mathematics. Abstract PDF. ISSN: 2508-1128. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

  12. Author Details

    African Journals Online (AJOL)

    Gyutorwa, Joseph Samson. Vol 12, No 4 (2017) - Articles In vivo ameliorative effect of methanolic extract of Boswellia dalzielli Hutch (Mebdh) stem bark on Triton X-100 induced hyperlipidaemia. Abstract PDF. ISSN: 1597-6343. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  13. Author Details

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    Omoegun, M. Vol 3, No 1 (2007) - Articles Effect of Parental Socio-Economic Status on Parental Care and Social Adjustment in the UBE Programme in Lagos State: Implications for Counselling Abstract. ISSN: 1595-8485. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  14. Author Index

    Indian Academy of Sciences (India)

    user1

    Astr. (2012) 33, 419–420. Author Index. 419. AGGARWAL SUNNY. Photoionization Cross-Section of Chlorine-like Iron, 291. AMBASTHA ASHOK see Das, A. C., 1. ARAKIDA HIDEYOSHI. Effect of Inhomogeneity of the Universe on a Gravitationally. Bound Local System: A No-Go Result for Explaining the Secular Increase in.

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    Abiola, J.O.. Vol 37, No 4 (2016) - Articles Immunomodulatory effect of Levamisole hydrochloride and Mentofin® in Newcastle disease vaccinated commercial broilers. Abstract PDF. ISSN: 0331-3026. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Ibrahim, Zein Shaban. Vol 14, No 6 (2017) - Articles Cardioprotective effects of curcumin against diabetes and nicotine combined oxidative stress. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Nyoungui, JE. Vol 8, No 4 (2014) - Articles Effect of experimental trypanosomosis on body weight, packed cells volume and reproductive characteristics in Gudali zebu and Namchi taurine bulls. Abstract PDF. ISSN: 1997-342X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  18. Author Details

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    Anti-oxidant and anti-inflammatory effects of rice bran and green tea fermentation mixture on lipopolysaccharideinduced RAW 264.7 macrophages. Abstract PDF. ISSN: 1596-9827. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Mukokoma, MM. Vol 2, No 1 (2009) - Articles Application and Effectiveness of New Public Management in National Water and Sewerage Corporation Abstract. ISSN: 2070-1748. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

  20. Author Details

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    Akintayo, DI. Vol 6, No 1 (2009) - Articles Managerial Effectiveness: Impact of Emotional Intelligence and Work-Family Role Conflict in Work Organizations in Nigeria. Abstract. ISSN: 1813-2227. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  1. Author Details

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    Farinmade, Ayomide E. Vol 12, No 13 (2013) - Articles Genotoxic and cytotoxic effects of food flavor enhancer, monosodium glutamate (MSG) using Allium cepa assay. Abstract PDF. ISSN: 1684-5315. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Bhatia, PG. Vol 12, No 2 (2009) - Articles Effects of Native and Pregelatinised Fonio starches on compression, mechanical and release properties of paracetamol tablet formulations. Abstract PDF. ISSN: 1026-552X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    Subhan, N. Vol 11 (2007) - Articles Sedative, Neuropharmacological And Antinociceptive Effect Of The Crude Extract Of Xylocarpus Granatum Stem Barks Abstract. ISSN: 1118-6267. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

  4. 76 FR 62068 - Delegation of Authorities

    Science.gov (United States)

    2011-10-06

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Delegation of Authorities Notice is hereby given that I... information. This delegation shall be exercised in accordance with the Department's applicable policies... effective date of this delegation. This delegation of authorities is effective upon date of signature...

  5. On the Question of the Diagnosis of Sudden Infant Death Syndrome

    Directory of Open Access Journals (Sweden)

    L. L. Nisevich

    2015-01-01

    Full Text Available Sudden Infant Death Syndrome (SIDS is one of the leading causes of postneonatal mortality of infants in most developed countries. This paper presents data on terminology and on the study of SIDS in developed countries, and also examines problems of SIDS diagnostic inRussia in comparison with the results of own researches, analyzes risk factors, which are universal as for SIDS, and also for perinatal and infant death in general. The large variability of SIDS diagnosis in Russia suggests that this diagnosis often does not comply with international standard: post-mortem examination of community-acquired sudden death cases is often carried out by a forensic expert, but not by a children's pathologist, and they do not use virological and microbiological methods of investigation. In some cases, there is no infant's record or case record from children's polyclinic.

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    Reza Ghorbani Mohammad Abadi, M. Vol 9, No 1S (2017): Special Issue - Articles The effect of group cognitive-behavioral therapy in reducing aggression in patients with thalassemia. Abstract PDF. ISSN: 1112-9867. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    Ojiezeh, TI. Vol 19, No 2 (2010) - Articles Effects of Cations on the Haematological Indices of Salmonella enterica Challenged Rabbits Abstract. ISSN: 1116-1043. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Nie, Zhong. Vol 14, No 5 (2017) - Articles Neuroprotective effect corilagin in spinal cord injury rat model by inhibiting nuclear factor-kB, inflammation and apoptosis. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Manga, A.A.. Vol 10, No 1 (2017) - Articles Effect of different concentrations of aqueous Ascophyllum nodosum extract on flowering and fruiting in some vegetables. Abstract PDF. ISSN: 2006-6996. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Johnson, Tosin. Vol 13, No 1 (2016) - Articles Antidiabetic effect of Crossopteryx febrifuga methanolic leaf extract in alloxan induced diabetic rats. Abstract. ISSN: 0189-8442. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Okolo, BN. Vol 15 (2011) - Articles Effects of Different Carbon Sources on Biosurfactant Production by a Pseudomonas fluorescens Isolate Abstract. ISSN: 1119-2283. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    African Journals Online (AJOL)

    Ojular, LS. Vol 18, No 1 (2011) - Articles Effectiveness of Vitamin C Consumption In Pregnancy On Dexamethasone Induced Low Birth Weight. Abstract. ISSN: 1117-4153. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

  13. Author Details

    African Journals Online (AJOL)

    Abrini, Jamal. Vol 3, No 3 (2006) - Articles Study on antigenotoxic effects of Moroccan medicinal plants and spices using the white/white + somatic assay in Drosophila Abstract. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  14. Author Details

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    Mezzoug, Nadya. Vol 3, No 3 (2006) - Articles Study on antigenotoxic effects of Moroccan medicinal plants and spices using the white/white + somatic assay in Drosophila Abstract. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  15. Author Details

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    El-Hamamsy, M. Vol 23 (2007) - Articles Effect Of Different Degrees Of Hepatic Dysfunction On The Pharmacokinetics Of Telmisartan Abstract. ISSN: 1110-6379. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

  16. Author Details

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    Ijeoma, MC. Vol 19, No 1 (2015) - Articles Effect of Personality Types of Extension Personnel on their Job Performance in Rivers State Agricultural Development Programme. Abstract PDF. ISSN: 2408-6851. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

  17. Author Details

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    Ramroop, S. Vol 7, No 1 (2009) - Articles Application of Negative Binomial Regression for Assessing Public Awareness of the Health Effects of Nicotine and Cigarettes Abstract PDF. ISSN: 1728-774X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  18. Author Details

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    Ugwumba, AAA. Vol 8 (2010) - Articles Effect of feeding frequencies on growth performance of Clarias gariepinus. Abstract. ISSN: 1596-972X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

  19. Author Details

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    Chan, Alice Yin Wa. Vol 27 (2017) - Articles The effectiveness of using a bilingualized dictionary for determining noun countability and article selection. Abstract PDF. ISSN: 2224-0039. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  20. Author Details

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    Alagbonsi, I.A.. Vol 4, No 1 (2016) - Articles Ameliorative effect of combined melatonin and vitamin C on Cannabis sativa-induced reproductive hormonal toxicity. Abstract PDF. ISSN: 2449-108X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  1. Author Details

    African Journals Online (AJOL)

    Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Vol 8 (2004) - Articles Further on stokes expansions for the finite amplitude water waves. Abstract · Vol 11 (2007) - Articles On the effects of wave steepness on higher order Stokes waves. Abstract. ISSN: 1116-4336.

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    Iya, S. Vol 12, No 2 (2013) - Articles Comparative study of the effects of treatment techniques on the thermal and frictional properties of Kenaf (Hibiscus canabinus) fibre reinforced brake pads. Abstract PDF. ISSN: 1607-9949. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

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    Agbekpornu, HG. Vol 7 (2008) - Articles Consumer Preferences for Rice Quality Characteristics in Accra and the Effects of these Preferences on Price Abstract. ISSN: 0855-5591. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Barakat, LAA. Vol 29, No 1 (2011) - Articles Effects of L-Carnitine and Taurine on associated biochemical changes in Alloxan induced diabetic rats. Abstract. ISSN: 1687-1502. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Abdulmajeed, W. Vol 3, No 1 (2015) - Articles Anti-nociceptive effects of taurine and caffeine in sciatic nerve ligated wistar rats: involvement of autonomic receptors. Abstract PDF. ISSN: 2449-108X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Owusu-Acheaw, M. Vol 19, No 1 (2007) - Articles Staff development and employee welfare practices and their effect on productivity in three special libraries in Ghana. Abstract. ISSN: 0855-3033. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Seo, Chang-Seob. Vol 14, No 5 (2017) - Articles Simultaneous determination and anti-inflammatory effects of traditional herbal medicine, Mahwang-tang. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Iyawe, V. Vol 7, No 1-2 (2008) - Articles Preliminary study on the effect of medicinal mushroom extract and timolol maleate on dexamethasone induced ocular hypertension in feline's eye model. Abstract PDF. ISSN: 1596-6941. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

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    Onyeke, CC. Vol 6, No 2 (2008) - Articles Studies on the Effects of Media on Growth and Nutritional Composition of Pleurotus Tuber-regium (Fries) Singer Mushroom Abstract. ISSN: 1596-7409. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Danjuma, Barnabas Sunday. Vol 15, No 1 (2017) - Articles The effect of Montessori Method on teaching cultural and creative arts in primary schools in Zaria, Nigeria Abstract. ISSN: 1596-8308. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Ogunjimi, Moses A. Vol 23, No 1 (2017) - Articles Short‑term Effect of Tamsulosin and Finasteride Monotherapy and their Combination on Nigerian Men with Benign Prostatic Hyperplasia Abstract PDF. ISSN: 1117-6806. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    Bola, Udegbe I. Vol 10, No 2 (2002) - Articles The Effects of Occupational Prestige, Marital Status and Technological Level of Job on Perception of Working Mothers Abstract. ISSN: 1117-1421. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Mahmoudi, F. Vol 9, No 1S (2017): Special Issue - Articles The effect of group cognitive-behavioral therapy in reducing aggression in patients with thalassemia. Abstract PDF. ISSN: 1112-9867. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Envuladu, E.A.. Vol 2, No 4 (2014) - Original Article Integrated disesase surveillance and response reporting: effects of training on primary healthcare workers in plateau state, Nigeria Abstract PDF. ISSN: 2467-8252. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    Agokei, CR. Vol 15, No 1 (2012) - Articles Effectiveness of Mindfulness Training in Fostering Tobacco Cessation among Undergraduates in a Nigerian University Abstract · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Muazu, J. Vol 12, No 2 (2009) - Articles Effects of Native and Pregelatinised Fonio starches on compression, mechanical and release properties of paracetamol tablet formulations. Abstract PDF. ISSN: 1026-552X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More ...

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    Sarpong, GD. Vol 31, No 3 (2011) - Articles Globalization of the Fashion Industry and Its Effects on Ghanaian Independent Fashion Designers Abstract PDF. ISSN: 0855-0395. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Odeniran, P.O.. Vol 30, No 2 (2015) - Articles Evaluating the effectiveness of varying concentrations of permethrin on ticks of genus Aponoma on Royal Pythons (Python Regius) Abstract. ISSN: 0856-1451. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Onyenekwu, CP. Vol 6, No 2 (2016) - Articles The Effectiveness of Clinician Education on the Adequate Completion of Laboratory Test Request Forms at a Tertiary Hospital Abstract PDF. ISSN: 2141-9248. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Rajendran, Kalidoss. Vol 10, No 1 (2011) - Articles Short Communication A study on the bactericidal effect of nisin purified from Lactococcus lactis. Abstract. ISSN: 1819-8678. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Obikeze, KC. Vol 61 (2008) - Articles Characterization and Cardiovascular Effects of (13S)-9α,13α-epoxylabda-6β(19),15(14)diol Dilactone, a Diterpenoid Isolated from Leonotis leonurus. Abstract PDF. ISSN: 0379-4350. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  2. Effects of protein concentration and heat treatment on concentration of digestible and metabolizable energy and on amino acid digestibility in four sources of canola meal fed to growing pigs.

    Science.gov (United States)

    Liu, Y; Song, M; Maison, T; Stein, H H

    2014-10-01

    Two experiments were conducted to determine DE and ME and the apparent ileal digestibility (AID) and the standardized ileal digestibility (SID) of CP and AA in 4 sources of canola meal (high-protein [CM-HP], high-temperature-processed [CM-HT], low-temperature-processed [CM-LT], and conventional [CM-CV] canola meal) and in conventional soybean meal (SBM) fed to growing pigs. In Exp. 1, 48 growing barrows (initial BW: 39.7 ± 1.58 kg) were individually housed in metabolism cages and randomly assigned to 6 treatments in a randomized complete block design with 2 blocks of 24 pigs and 8 replicate pigs per treatment. The 6 diets included a corn-based basal diet and 5 diets that were formulated by mixing corn and 1 of the sources of canola meal (39.0% inclusion) or SBM (28.5% inclusion). Feces and urine were collected for 5 d following a 5-d adaptation period. The DE and ME in each source of canola meal and in SBM were calculated using the difference procedure. The DE and ME in the 4 sources of canola meal were less (P sources of canola meal. In Exp. 2, 12 growing barrows (initial BW: 34.0 ± 1.41 kg) that had a T-cannula installed in the distal ileum were randomly allotted to a repeated 6 × 6 Latin square design with 6 diets and 6 periods in each square. Five diets that contained 35% SBM or 45% of 1 of the 4 sources of canola meal as the sole source of CP and AA were formulated, and a N-free diet was also used. Each period lasted 7 d and ileal digesta were collected on d 6 and 7 of each period. The AID and SID of CP and all AA in SBM were greater (P sources of canola meal. Compared with CM-CV, CM-HP had greater (P < 0.05) AID of Ile, Lys, Asp, Cys, and Pro and greater (P < 0.05) SID of Lys and Cys. However, no differences between CM-HT and CM-LT were observed. In conclusion, regardless of the concentration of CP and the processing used, canola meal provides less DE and ME to pigs than corn and SBM, and the SID of AA in canola meal is less than in SBM. The processing

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    Afshar, M. Vol 8, No 2 (2016): Special Issue: Part 2 - Articles Evaluating the effects of climate on weathering processes of rocks based on Peltier models in Kermanshah province. Abstract PDF. ISSN: 1112-9867. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More ...

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    Ashaye, OA. Vol 5, No 10 (2006) - Articles Effect of gamma irradiation on moisture sorption isotherms of cowpeas. Abstract PDF. ISSN: 1684-5315. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

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    Builders, PF. Vol 14 (2009) - Articles Effect of pH of Dispersion on Some Physicochemical Properties of Regenerated Cashew Gum Abstract PDF. ISSN: 1118-1028. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Shihusa, H. Vol 10, No 2 (2005) - Articles Effects Of Advance Organizers On Students\\' Achievement In Biology: A Case Study Of Bureti District, Kenya Abstract. ISSN: 1118-5570. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Chaouachi, A. Vol 10, No 1 (2015) - Articles Effect of active warm-up duration on morning short-term maximal performance during Ramadan Abstract PDF. ISSN: 1819-6357. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Ngozi, Anaka Ogochukwu. Vol 10, No 3 (2013) - Articles Analgesic effect of the aqueous seed extract of Persea Americana Mill (Lauraceae) Abstract. ISSN: 1596-8499. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Widyawaruyanti, A. Vol 4, No 3 (2007) - Articles Apoptosis Inducing Effect Of Andrographolide On TF-47 Human Breast Cancer Cell Line Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Koona, OES. Vol 9, No 2 (2012) - Articles Effect of the Aqueous Extract of Justicia insularis T. Anders (Acanthaceae) on Ovarian Folliculogenesis and Fertility of Female Rats Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Medugu, D W. Vol 18, No 2 (2006) - Articles Design and development of solar still for effectiveness in eliminating microbial contamination and salt in Mubi, Adamawa State, Nigeria Abstract PDF. ISSN: 1595-0611. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More ...

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    Kirsten, GJC. Vol 35, No 3 (2015) - Articles The nature of workplace bullying experienced by teachers and the biopsychosocial health effects. Abstract PDF. ISSN: 2076-3433. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Penning, Susan Louise. Vol 22, No 2 (2010) - Articles Research Paper Bullying boys: the traumatic effects of bullying in male adolescent learners. Abstract. ISSN: 1728-0591. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Hayelom, K. Vol 12, No 4 (2012) - Articles Methanolic effect of Clerodendrum myricoides root extract on blood, liver and kidney tissues of mice. Abstract PDF. ISSN: 1680-6905. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Joseph, L. Vol 11, No 2 (2008) - Articles Hepatoprotective Effect of Clerodendrum inerme Linn. Ethanolic Extract Abstract PDF. ISSN: 1026-552X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

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    Adeniyi, FAA. Vol 25, No 2 (2010) - Articles Effects of Methionine Containing Paracetamol Formulation on Serum Vitamins and Trace Elements in Male Rats Abstract PDF. ISSN: 0794-859X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Fasasi, KA. Vol 8 (2010) - Articles Effect of age of honeybee queens of Apis mellifera adansonii (Hymenoptera: apidae) on the rate of brood production in modern bee-hives. Abstract. ISSN: 1596-972X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Ambali, SF. Vol 11, No 2 (2013) - Articles Haematogical changes induced by subchronic glyphosate exposure: Ameliorative effect of zinc in Wistar rats. Abstract PDF. ISSN: 1595-093X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Akaninyene, OU. Vol 4, No 1 (2015) - Articles Determinants of Effective Internal Control System in Nigerian Banks Abstract PDF. ISSN: 2227-5444. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

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    Victor, John C. Vol 28, No 3 (2016) - Articles Research Article (New England Journal of Medicine) Effect of human rotavirus vaccine on severe diarrhea in African infants. Abstract PDF. ISSN: 1995-7262. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Dzasu, WE. Vol 4, No 1 (2011) - Articles Effects of Groundnut Husk Ash-blended Cement on Chemical Resistance of Concrete Abstract PDF. ISSN: 1596-6035. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Ortese, PT. Vol 16, No 2 (2008) - Articles Effects Of Emotional Intelligence On Marital Adjustment Of Couples In Nigeria Abstract. ISSN: 1117-1421. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

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    Osinubi, AAA. Vol 13, No 2 (2014) - Articles Assessment of the effects of parenteral quinine on testicular histology and sperm parameters in wistar rats. Abstract PDF. ISSN: 1596-6941. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Tsado, TY. Vol 8, No 2 (2013) - Articles Effect of municipal solid waste ash on comprehensive strength characteristics of an interlocking block masonry wall. Abstract. ISSN: 0795-5111. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Obochi, GO. Vol 25, No 1 (2010) - Articles Effect of Melatonin and Caffeine Interaction on Caffeine Induced Oxidative Stress and Sleep Disorders Abstract PDF. ISSN: 0794-859X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Akintunde, O O. Vol 2 (2012) - Articles Improving listening skills of tertiary level students for effective information retrieval. Abstract. ISSN: 1119-9210. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

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    Wang, Ming-Rui. Vol 13, No 2 (2016) - Articles Effects of acupuncture on rheumatoid arthritis: a systematic review and meta-analysis. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Olabisi, JO. Vol 7, No 1 (2013) - Articles Appraisal of Strategic Alliances and Corporate Effectiveness Abstract PDF. ISSN: 2070-0083. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...

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    Achinike, P N. Vol 2, No 1 (2007) - Articles The effects of Aloe vera [gel] on clotting time, prothrombin time and plasma fibrinogen concentration in albino Wistar rats. Abstract. ISSN: 0795-3038. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Pattiyathanee, P. Vol 8, No 19 (2009) - Articles Effect of curcumin on Helicobacter pylori biofilm formation. Abstract PDF. ISSN: 1684-5315. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

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    Aryanfar, S. Vol 6, No 2 (2017) - Articles Effects of curcumin on sperm parameters abnormalities induced by morphine in rat. Abstract PDF. ISSN: 2026-6294. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions ...

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    Ahn, T. Vol 37, No 2 (2015) - Articles Effect of Trust and Risk on Purchase Intentions in Online Secondary Ticketing: Sport Consumers and Ticket Reselling Abstract. ISSN: 0379-9069. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Okuthe, GE. Vol 37, No 3 (2012) - Articles Sublethal effects of carbaryl on embryonic and gonadal developments of zebrafish Danio rerio. Abstract. ISSN: 1727-9364. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Fagbenro, JA. Vol 13, No 1 (2013) - Articles Effect of Saw Dust Biochar and NPK 15:15:15 Inorganic Fertilizer on Moringa oleifera Seedlings Grown in an Oxisol. Abstract PDF. ISSN: 1117-9996. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Dangora, DB. Vol 4, No 1 (2011) - Articles Effect of Colchicine Induced Mutagenesis on Growth and Yield of Sesame (Sesamum indicum L.) Abstract PDF. ISSN: 2006-6996. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Ejuh, Geh Wilson. Vol 20 (2012) - Articles Linearity and Non-linearity of Photorefractive effect in Materials using the Band transport Model Abstract. ISSN: 1116-4336. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Babalola, OA. Vol 12, No 2 (2008) - Articles Effects of Kaolin particle size and annealing temperature on the Resistivity of Zinc- Kaolin Composite Resistors Abstract PDF. ISSN: 1119-8362. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Enaibe, BU. Vol 7, No 1-2 (2008) - Articles Histological Studies Of The Teratogenic Effects Of Camphor On The Developing Kidney Of The Wistar Rats Abstract. ISSN: 1596-6569. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Xiong, You-Xiong. Vol 14, No 1 (2017) - Articles Evaluation of effectiveness in a novel wound healing ointment-crocodile oil burn ointment. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Ebosie, CV. Vol 23, No 1 (2005) - Articles Effects of cold storage and storage over fireplace on the rheological functions of “Ogbono” (Irvingia gabonensis) Abstract. ISSN: 0189-7241. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Abu-Sinna, Gamal. Vol 2 (2000) - Articles Effect of Leiurus quinquestriatus venom and venom fractions on cells cultured in vitro. Abstract PDF. ISSN: 1110-6859. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Uguru, M O. Vol 21 (2005) - Articles Effect of methanolic extract of Asparagus pubescens root on non-vascular smooth muscle in experimental animals. Abstract. ISSN: 0303-691X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Edet, AO. Vol 12, No 1 (2012) - Articles Effects of Corporal Punishment on Disciplinary Control of Secondary School Students in Calabar Metropolis of Nigeria Abstract. ISSN: 1596-6224. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Bhadauria, Archana S. Vol 5, No 1 (2013) - Articles A generalised prey-predator type model of immunogenic cancer with the effect of immunotherapy. Abstract PDF. ISSN: 2141-2839. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Oyeyipo, IP. Vol 18, No 2 (2011) - Articles Effects of Oral Administrationof Nicotine on Blood Glucose, Electrolytes and Lipid Profile in Albino Rats Abstract. ISSN: 1117-4153. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Carolus, Peter. Vol 11, No 1 (2007): Special Issue - Articles Effects on the employment relationship of the insolvency of the employer: A worker perspective. Abstract PDF. ISSN: 2077-4907. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Atunwa, SA. Vol 8, No 3 (2011) - Articles Neuropharmacological effects of Nigerian honey in mice. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...

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    Thippeswamy, A.H.M. Vol 9, No 2 (2006) - Articles Some neuropharmacological effects of the methanolic root extract of Cissus quadrangularis in mice. Abstract PDF. ISSN: 1119-5096. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Ibrahim, BO. Vol 8, No 3 (2011) - Articles Neuropharmacological effects of Nigerian honey in mice. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...

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    Kruger, HB. Vol 29, No 1 (2004) - Articles Addressing domestic violence: to what extent does the law provide effective measures? Abstract. ISSN: 0258-252X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions ...

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    Okeke, CP. Vol 24, No 1 (2009) - Articles Effect Of CARICAPRYL-99 Seed Alkaloid Extract On The Serum Levels Of Sex Hormones And Pituitary Gonadotrophins In Male Albino Rats Abstract PDF. ISSN: 0794-859X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    Gyamfi, GD. Vol 32, No 1 (2012) - Articles Assessing the Effectiveness of Credit risk Management Techniques of Microfinance firms in Accra Abstract PDF. ISSN: 0855-0395. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Okpala, K C. Vol 18, No 1 (2006) - Articles Solar flare effects and storm sudden commencement even in Geomagnetic H, Y and Z fields at Euro-African observatories. Abstract PDF. ISSN: 1595-0611. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Lele, KC. Vol 24, No 2 (2012) - Articles Toxic effect of carica papaya bark on body weight, haematology, and some biochemical parameters. Abstract PDF. ISSN: 0795-8080. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Mondal, KC. Vol 62 (2009) - Articles The Effect of Synthesis Parameters on the Catalytic Synthesis of Multiwalled Carbon Nanotubes using Fe-Co/CaCO3 Catalysts Abstract PDF PDF. ISSN: 0379-4350. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Nwosu, EC. Vol 12, No 1 (2014) - Articles An Assessment Of The Effectiveness Of Collaborative Cost Reduction Model As A Control Approach To Sluggish Migration From IPV4 To IPV6 In Nigeria Abstract. ISSN: 1116-5405. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

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    Pretorius, EJ. Vol 46, No 2 (2012) - Articles Butterfly effects in reading? The relationship between decoding and comprehension in Grade 6 high poverty schools. Abstract. ISSN: 0259-9570. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Ogunkuade, Idowu Michael. Vol 6, No 2 (2017) - Articles Effects of caffeine and anxiety level on psychomotor performance. Abstract PDF. ISSN: 2227-5452. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

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    Ayad, Amar. Vol 33 (2016) - Articles The effect of surface roughness on the performances of liner-piston ring contact in internal combustion engine. Abstract PDF. ISSN: 2352-9717. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Aghanya, IO. Vol 1 (2012) - Articles Computer Graphics and Special Effects: A creative way of producing Igbo-themed movies for the global audience. Abstract PDF. ISSN: 2346-7126. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Akinsulore, Adedoyin. Vol 7, No 1 (2016) - Articles The effects of legislation on corporate social responsibility in the minerals and mines sector of Nigeria Abstract PDF. ISSN: 2467-8392. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  3. Regulatory authority infrastructure for Namibia

    International Nuclear Information System (INIS)

    Shangula, K.

    2001-01-01

    The Republic of Namibia is participating in the International Atomic Energy Agency's Model Project for the Improvement of National Regulatory Authority Infrastructures in Member States. The paper illustrates our experience in solving problems and difficulties confronted in establishing an effective regulatory authority operating within the existing national infrastructure that should be supported by the Government. An effective regulatory authority is seen as part of the wider administrative scope of our Government through ministerial mandates given by the State from time to time, guaranteeing its independence when implementing legal provisions under statutes. Sections of the report illustrate our experience in the following areas: 1. National radiation protection policy 2. Structure of our national regulatory authority 3. Laws and regulations 4. Provisions for notification, authorization and registration 5. In-depth security measures for radiation sources and radioactive material 6. Systems for the inspection of radiation sources, radioactive materials, enforcement of legal provisions 7. Extent of the applications of radiation sources and radioactive materials in the country. The paper provides information regarding existing Government policy on radiation protection; structure and legal aspects of the national regulatory, including statutes and regulations; the extent of application and uses of radiation sources and security of radioactive materials; human resources: strengths and constraints; management practices and financing of regulatory authority; and plans for emergency recovery of orphan sources. National plans for management of disused sources, recovery of orphan sources, abnormal emergencies, communication of information to affected persons on exposure effects, and the safety training of persons using these applications are discussed. the paper provides a summary and some suggestions of the way forward for Namibia. (author)

  4. E-Government Attempts in Small Island Developing States: The Rate of Corruption with Virtualization.

    Science.gov (United States)

    Sari, Arif

    2017-12-01

    In recent years, many Small Island Developing State (SIDS) governments have worked to increase openness and transparency of their transactions as a means to enhance efficiency and reduce corruption in their economies. In order to achieve a cost-effective and efficient strategy to implement a transparent government, Information Communication Technologies offer an opportunity of virtualization by deploying e-government services to promote transparency, accountability and consistency in the public sector and to minimize corruption. This paper explores the potential impact of government virtualization by SIDS and against corruption by comparing the corruption perception index (CPI) rates of 15 SIDS countries. The CPI relates to the degree by which corruption is perceived to exist among public officials and politicians by business people and country analysts. In order to reveal the long-term impact of virtual deployment and its consequences on corruption, an in-depth case analysis based on the CPI index rates was conducted on the deployment of the e-government system in Cyprus.

  5. [Parents have accepted the advice on how to prevent sudden infant death].

    Science.gov (United States)

    Alm, Bernt; Wennergren, Göran; Erdes, Laslo; Möllborg, Per; Pettersson, Rolf; Aberg, Nils; Norvenius, S Gunnar

    2004-04-01

    We have compared 430 healthy Swedish infants born between 1991 and 1995 with 599 healthy, six months old infants born in 2002, regarding the prevalence of risk factors for SIDS. Following the introduction of the campaign to reduce the risk of SIDS in Sweden in 1992, we could see a decrease in prone sleeping from 32% to 7% together with an increase in supine sleeping from 35% to 44%. Maternal smoking during pregnancy has gone down from 24% to 10%. The prevalence of breast feeding, already high in Sweden in the 90s, was largely unchanged, 69% at six months of age in 2002. This comparison shows that parents of small infants have accepted the advice on ways to reduce the risk of SIDS, and that information given at infant welfare clinics is still effective ten years later. Further improvements are possible by changing the side sleeping position to supine, and by decreasing tobacco smoking among pregnant mothers.

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    Arinze, CU. Vol 10, No 1-2 (2008) - Articles The effect of leave extracts of Carica papaya and Psidium guajava on activities of liver enzymes of Albino Rats Abstract · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Dan, B.S.C.. Vol 8, No 2 (2016) - Articles Effects of land cover change on rangeland vegetation in W Biosphere Reserve, Benin Republic, West Africa Abstract PDF. ISSN: 2141-1778. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Bai, Peter J. Vol 15, No 2 (2016) - Articles Neuroprotective effect of Zhen Tian Wan on pial strip-induced cognitive impairments and anti-oxidant status in rats. Abstract PDF. ISSN: 1118-1028. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Osiki, JO. Vol 6, No 1 (1998) - Articles The Clinical Investigation on The Effective Application of Prayer and Faith Builder in Altering The Hither-To Situation of Some Non-Diagnostic Apa Illness Abstract. ISSN: 0794-0831. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    El-Bahr, S M. Vol 25, No 2 (2007) - Articles The Protective Effect Of Turmeric On Iron Overload In Albino Rats Abstract. ISSN: 1687-1502. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

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    Abou'l Ezz, HS. Vol 9, No 2 (2000) - Articles Neurochemical changes in amino acid nuerotransmitters in the medulla of reseprinized rats under the effect of TCP Abstract. ISSN: 1110-5593. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Akikli, AB. Vol 3, No 1 (2010) - Articles The Effect of Ramadan Fasting on the Kidney Function of Renal Transplant Recipients Abstract PDF. ISSN: 1858-554X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Munguri, M W. Vol 5, No 2 (2001): - Articles The effect of rate and time of application of Nitrogen on maize yield in Chinyika Resettlement area, Zimbabwe Abstract. ISSN: 1029-9645. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Asere, AA. Vol 14, No 2 (2005) - Articles The effect of turbidity of spherical particles on the thermal performance of a solar water heater. Abstract. ISSN: 1019-1593. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Murluki, AW. Vol 14, No 2 (2012) - Articles Effect of rain water harvesting and drip irrigation on crop performance in an arid and semi-arid environment. Abstract. ISSN: 1561-7645. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Osarolube, E. Vol 7, No 2 (2008) - Articles Single effect green house type solar still for portable water supply. Abstract. ISSN: 1118-1931. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

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    Kumar, M. Vol 78, No 1 (2008) - Articles Effect of aspect on distribution pattern of Anogeissus latifolia (Wall Ex Bedd) in subtropical belt of Garhwal Himalaya, India Abstract. ISSN: 2408-8137. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Kisinza, W N. Vol 2, No 2 (2001): Supplement - Articles Field trial of bifenthrin as an effective insecticide for the control of Malaria vectors. Abstract PDF. ISSN: 1821-9241. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Bilbis, LS. Vol 13, No 2 (2006) - Articles Effect of repeated administration of Damiana on selected kidney functions of male rats. Abstract. ISSN: 1117-4153. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

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    Osamuyi, O. Vol 7, No 1 (2000) - Articles Effects of Internal Control Training on the Locus of Control of Some School Going Adolescents in Benin City. Abstract. ISSN: 0794-0831. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Wannang, N.N. Vol 23, No 1-2 (2008) - Articles Hypoglycaemic and hypolipidaemic effects of the aqueous leaf extract of murraya koenigii in normal and alloxan – diabetic rats. Abstract PDF. ISSN: 0794-859X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More ...

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    Adejobi, KB. Vol 4, No 1 (2010) - Articles Effect of Neem (Azadirachta Indica) Leaf Extracts on the Rot Fungus (Fusarium Spp) Isolated from Kola Nuts Abstract. ISSN: 1597-913X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Diaf, Mustapha. Vol 11, No 1 (2016) - Articles Effect of IL-1β and IL-1RN polymorphisms in carcinogenesis of the gastric mucosa in patients infected with Helicobacter pylori in Algeria Abstract PDF. ISSN: 1819-6357. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    Mustapha, OT. Vol 20, No 1 (2014) - Articles Effects of nitrous acid on growth and yield of Digitaria exilis (Haller) Abstract PDF. ISSN: 1118-0579. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

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    Laiyemo, OO. Vol 5, No 1 (2008) - Articles The effects of advertising on sales in the pharmaceutical industry in Nigeria - A survey. Abstract. ISSN: 1596-8499. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions ...

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    Arowolo, RO. Vol 16, No 1 (1989) - Articles Toxic effects of the extracts of Eugenia uniflora Linn. in rats. Abstract. ISSN: 0331-2062. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...

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    Mars, M. Vol 18, No 3 (2006) - Articles The effect of icepack cooling on skin and muscle temperature at rest and after exercise. Abstract PDF. ISSN: 2078-516X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Dino, A. Vol 1, No 3 (2012) - Articles Effects of Cheating on Accurate Assessment Abstract PDF. ISSN: 2305-3372. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER ...

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    Agboola, IO. Vol 4, No 5 (2010) - Articles Anxiolytic effect of aridanin isolated from Tetrapleura tetraptera in mice. Abstract PDF. ISSN: 1997-342X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

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    Gulsen, HG. Vol 17, No 1 (2014) - Articles Effect of the number of portal area on modified histological activity index of viral hepatitis and histological findings. Abstract PDF. ISSN: 1119-3077. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Ippolito, P.D.. Vol 6, No 2 (2016) - Articles The effect of renal diet in association with enalapril or benazepril on proteinuria in dogs with proteinuric chronic kidney disease. Abstract PDF. ISSN: 2218-6050. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Galam, NZ. Vol 14, No 3 (2011) - Articles Anti-inflammatory and Analgesic Effects of Aqueous Extract of Aloe Vera (Aloe barbadensis) in Rats Abstract PDF. ISSN: 1119-5096. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

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    Nwaoguala, CNC. Vol 9, No 3 (2010) - Articles The effect of manganese on early growth of fluted pumpkin (telfairia occidentalis hook f) in an ultisol. Abstract PDF. ISSN: 1119-7455. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Sharada, A.C. Vol 10, No 3 (2007) - Articles Antiangiogenic effects of synthetic analogs of curcumin in vivo. Abstract PDF. ISSN: 1119-5096. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

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    Jalili, F. Vol 6, No 2 (2017) - Articles Effects of curcumin on sperm parameters abnormalities induced by morphine in rat. Abstract PDF. ISSN: 2026-6294. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

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    Jalili, C. Vol 6, No 2 (2017) - Articles Effects of curcumin on sperm parameters abnormalities induced by morphine in rat. Abstract PDF. ISSN: 2026-6294. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

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    Abdel-aziz, A. Vol 24, No 1 (2006) - Articles Effect of rice bran oil on hypercholesterolemia and tibial calcium in rat. Abstract. ISSN: 1687-1502. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

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    Dume, Bayu. Vol 10, No 3 (2016) - Articles Effect of biochar on soil properties and lead (Pb) availability in a military camp in South West Ethiopia Abstract PDF. ISSN: 1996-0786. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Aholuwoye, CO. Vol 7, No 2 (2005) - Articles Electrostatic effects of ionosable groups on the reactivity of the and CysF9[93]β sulphydryl group in haemoglobins. Abstract. ISSN: 0794-4896. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Wilson, MM. Vol 16, No 2 (2015) - Articles Study of the effect of HFE gene mutations on iron overload in Egyptian thalassemia patients. Abstract PDF. ISSN: 1110-8630. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Buri, M M. Vol 6 (2007) - Articles Effect of Cropping System and Mineral Fertilizer on Root Yield of Cassava Abstract. ISSN: 0855-5591. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...

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    Tor-Agbidye, S. Vol 9, No 2 (2011) - Articles The psychological effects of giving birth to a child with meromelia. Abstract. ISSN: 1118-4647. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

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    Zhang, Zi-Ran. Vol 14, No 1 (2017) - Articles Evaluation of effectiveness in a novel wound healing ointment-crocodile oil burn ointment. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Zaki, W S. Vol 25, No 1 (2007) - Articles The effect of snake venom metalloproteinase/disintergrin like activity on the liver of albino white mice. Abstract. ISSN: 1687-1502. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Meduna, A J. Vol 5 (2007) - Articles Effect of disturbance on laying pattern and hatchability of feral helmet guinea fowl (numida meleagris galleata pallas) egg. Abstract. ISSN: 1596-972X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Boa, K. Vol 32, No 2 (2012) - Articles Effect of Some Agronomic Practices to Increase Maize Yield in Ghana Abstract PDF. ISSN: 0855-0395. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

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    Rooeintan, Y. Vol 8, No 4 (2016): Special Issue - Articles The effect of aqueous extract of caraway seed (Carum carvi) on cholecystokinin hormone in male rat. Abstract PDF. ISSN: 1112-9867. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Mukumbo, FE. Vol 44, No 4 (2014) - Articles Effect of Moringa oleifera leaf meal on finisher pig growth performance, meat quality, shelf life and fatty acid composition of pork. Abstract PDF. ISSN: 2221-4062. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Mabusela, TP. Vol 44, No 4 (2014) - Articles Effect of Moringa oleifera leaf meal on finisher pig growth performance, meat quality, shelf life and fatty acid composition of pork. Abstract PDF. ISSN: 2221-4062. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...

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    Tafesse, Geremew. Vol 6, No 2 (2006) - Articles Antifertility effect of aqueous and ethanol extracts of the leaves and roots of Asparagus africanus in rats. Abstract PDF. ISSN: 1680-6905. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Mbuthia, P.G.. Vol 65, No 3 (2017) - Articles Effect of ruminal plastic bags on wellbeing of goats. Abstract. ISSN: 0378-9721. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News.

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    Msuya, F. Vol 6, No 1 (2008) - Articles The Effect of Stocking Density on the Performance of the Seaweed Ulva reticulata as a Biofilter in Earthen Pond Channels, Zanzibar, Tanzania Abstract PDF. ISSN: 0856-860X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    Owen, E. Vol 39, No 1 (2006) - Articles Memory and food intake in sheep: Effects of previous exposure to straw on intake and behaviour later in life. Abstract. ISSN: 0855-0042. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

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    Amkpa, Samuel Arubam. Vol 2, No 2 (2011) - Articles Effects of corporate culture on the implementation of automation in libraries of federal universities in the North–East Zone of Nigeria Abstract PDF. ISSN: 2360-994X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

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    Osadolor, HB. Vol 8, No 3 (2014) - Articles Effect of academic stress on serum cortisol level and CD4 cell count in young male postgraduate students in Okada, Nigeria Abstract PDF. ISSN: 1997-342X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

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    Afifi, MM. Vol 29, No 1 (2011) - Articles Effects of reduced glutathion and vitamin c on cisplatin-induced hepatotoxicity in rats. Abstract. ISSN: 1687-1502. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

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    Erasmus, H. Vol 19, No 2 (2007) - Articles Effect of a prevention programme on the incidence of rugby injuries among 15- and 16-year-old schoolboys. Abstract PDF. ISSN: 2078-516X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    Onyekwelu, K C. Vol 3, No 3 (2006) - Articles Effect Of Crude Oil And Its Products On Bilirubin Of African Catfish Clarias gariepinus. Abstract. ISSN: 1597-3115. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    Ofokansi, KC. Vol 4, No 1 (2006) - Articles Effects of garcinia kolaseed extract on the in-vitro anti bacterial action of some penicillin analogues. Abstract. ISSN: 1596-7409. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

  20. Author Details

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    Taher, M. N. M. Vol 9, No 7S (2017) - Articles Effects of advera® warm mix additive on the rheological properties of unaged and short term aged asphalt binders. Abstract PDF. ISSN: 1112-9867. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  1. Author Details

    African Journals Online (AJOL)

    Abdulkarim, A. Vol 17, No 1 (2017) - Articles Effects of size and site factors on the availability of a standalone microgrid. Abstract PDF. ISSN: 1116-5405. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

  2. Author Details

    African Journals Online (AJOL)

    Kibor, D K. Vol 91, No 1 (2014) - Articles Effects of Enteral Glutamine Supplementation on Reduction of Infection in Adult Patients with Severe Burns Abstract PDF. ISSN: 0012-835X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

  3. Author Details

    African Journals Online (AJOL)

    Dyomina, Ye.V. Vol 54, No 1 (2018) - Articles The effect of the essential oils of lavender and rosemary on the human short-term memory. Abstract PDF. ISSN: 2090-2948. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

  4. Impact of China's Public Hospital Reform on Healthcare Expenditures and Utilization: A Case Study in ZJ Province.

    Directory of Open Access Journals (Sweden)

    Hao Zhang

    Full Text Available High drug costs due to supplier-induced demand (SID obstruct healthcare accessibility in China. Drug prescriptions can generate markup-related profits, and the low prices of other medical services can lead to labor-force underestimations; therefore, physicians are keen to prescribe drugs rather than services. Thus, in China, a public hospital reform has been instituted to cancel markups and increase service prices.A retrospective pre/post-reform study was conducted in ZJ province to assess the impact of the reform on healthcare expenditures and utilization, ultimately to inform policy development and decision-making. The main indicators are healthcare expenditures and utilization.Post-reform, drug expenditures per visit decreased by 8.2% and 15.36% in outpatient and inpatient care, respectively; service expenditures per visit increased by 23.03% and 27.69% in outpatient and inpatient care, respectively. Drug utilization per visit increased by 5.58% in outpatient care and underwent no significant change in inpatient care. Both were lower than the theoretical drug-utilization level, which may move along the demand curve because of patient-initiated demand (PID; this indicates that SID-promoted drug utilization may decrease. Finally, service utilization per visit increased by 6% in outpatient care and by 13.10% in inpatient care; both were higher than the theoretical level moving along the demand curve, and this indicates that SID-promoted service utilization may increase.The reform reduces drug-prescription profits by eliminating drug markups; additionally, it compensates for service costs by increasing service prices. Post-reform, the SID of drug prescriptions decreased, which may reduce drug-resource waste. The SID of services increased, with potentially positive and negative effects: accessibility to services may be promoted when physicians provide more services, but the risk of resource waste may also increase. This warrants further research

  5. Long-term planning in Small Islands Developing States under a changing climate

    Science.gov (United States)

    Rozenberg, J.

    2017-12-01

    This paper presents an analytical framework and decision-making tool tailored to Small Islands Developing States (SIDS), to help them address future climate change challenges. SIDS are a diverse group of countries but all characterized by insularity, geographic remoteness, small economy and population size. SIDS are highly exposed and vulnerable to natural disasters, with average annual losses between 1 and 10% of GDP depending on the country. Vulnerability in SIDS is worsened by poor development planning and the countries' limited ability to respond and manage the risks. Infrastructure is a large share of the fixed capital stock in SIDS, most infrastructure assets are highly critical due to the lack of redundancy in networks and they are often highly vulnerable to natural hazards. Remoteness means that when infrastructure assets are damaged, reconstruction costs are larger than anywhere else, which narrows fiscal space, which in turn leads to deferred maintenance problems and raises the vulnerability to future events. In this context, and with climate change worsening the challenges SIDS face at an uncertain pace and intensity, decision-makers and international donors have to answer difficult questions. Does it make sense to spend increasing amounts of money in infrastructure given the level of debts SIDS face and the economic losses resulting from the regular disruption of infrastructure assets? How should sectors be prioritized? Should long-term plans consider "migration with dignity" as a potential option, especially for low-lying atolls? To help answer these questions, methods for decision-making under deep uncertainty, which rely on large numbers of model runs to identify the vulnerabilities of strategies, are particularly appropriate. The small population size of SIDS and simplicity of their infrastructure networks allows building system models coupled with household surveys and testing a range of different policy options, including unconventional policies

  6. Procedure for Development and Establishment of Indicators to Measure the Effectiveness of Customs Authority and its Departments

    Directory of Open Access Journals (Sweden)

    July G. Kishinskiy

    2016-12-01

    Full Text Available In this article author analyzes the organizational and legal framework for the development and establishment of indicators for assessing the effectiveness of the activities of the customs body of the Russian Federation and its structural divisions at the present stage. In the conclusion author states that the current performance indicators for the performance of customs authorities and their structural units are a system of great importance in the practical activities of customs officials, cover the implementation of the strategic goal of the customs service, most of the tasks and functions established by the state for customs officers and are "Indicator" of their achievement, allowing to identify "weaknesses" in the current work and to take new accurate and effective management solutions.

  7. Gender, job authority, and depression.

    Science.gov (United States)

    Pudrovska, Tetyana; Karraker, Amelia

    2014-12-01

    Using the 1957-2004 data from the Wisconsin Longitudinal Study, we explore the effect of job authority in 1993 (at age 54) on the change in depressive symptoms between 1993 and 2004 (age 65) among white men and women. Within-gender comparisons indicate that women with job authority (defined as control over others' work) exhibit more depressive symptoms than women without job authority, whereas men in authority positions are overall less depressed than men without job authority. Between-gender comparisons reveal that although women have higher depression than men, women's disadvantage in depression is significantly greater among individuals with job authority than without job authority. We argue that macro- and meso-processes of gender stratification create a workplace in which exercising job authority exposes women to interpersonal stressors that undermine health benefits of job authority. Our study highlights how the cultural meanings of masculinities and femininities attenuate or amplify health-promoting resources of socioeconomic advantage. © American Sociological Association 2014.

  8. Effect of diet composition on acid-base balance in adolescents, young adults and elderly at rest and during exercise.

    Science.gov (United States)

    Hietavala, E-M; Stout, J R; Hulmi, J J; Suominen, H; Pitkänen, H; Puurtinen, R; Selänne, H; Kainulainen, H; Mero, A A

    2015-03-01

    Diets rich in animal protein and cereal grains and deficient in vegetables and fruits may cause low-grade metabolic acidosis, which may impact exercise and health. We hypothesized that (1) a normal-protein diet with high amount of vegetables and fruits (HV) induces more alkaline acid-base balance compared with a high-protein diet with no vegetables and fruits (HP) and (2) diet composition has a greater impact on acid-base balance in the elderly (ELD). In all, 12-15 (adolescents (ADO)), 25-35 (young adults (YAD)) and 60-75 (ELD)-year-old male and female subjects (n=88) followed a 7-day HV and a 7-day HP in a randomized order and at the end performed incremental cycle ergometer tests. We investigated the effect of diet composition and age on capillary (c-pH) and urine pH (u-pH), strong ion difference (SID), partial pressure of carbon dioxide (pCO2) and total concentration of weak acids (Atot). Linear regression analysis was used to examine the contribution of SID, pCO2 and Atot to c-pH. In YAD and ELD, c-pH (P⩽0.038) and u-pH (Pdiet-induced acid-base changes.

  9. 75 FR 64753 - Options Price Reporting Authority; Notice of Filing and Immediate Effectiveness of Proposed...

    Science.gov (United States)

    2010-10-20

    ...-OPRA-2003-01. OPRA reorganized as a limited liability company effective as of January 1, 2010, and the current OPRA Plan is entitled ``Limited Liability Company Agreement of Options Price Reporting Authority...

  10. Author Details

    African Journals Online (AJOL)

    Hashish, Hagar A. Vol 14, No 1 (2015) - Articles Effect of curcumin on the expression of Caspase‑3 and Bcl‑2 in the spleen of diabetic rats. Abstract. ISSN: 1596-2393. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

  11. Author Details

    African Journals Online (AJOL)

    Chilaka, KC. Vol 5, No 1 (2003) - Articles The effect of L-Ascorbic acid on the choline chloride toxicity in mice. Abstract · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER ...

  12. Surface-Induced Dissociation of Protein Complexes in a Hybrid Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Jing; Zhou, Mowei; Gilbert, Joshua D.; Wolff, Jeremy J.; Somogyi, Árpád; Pedder, Randall E.; Quintyn, Royston S.; Morrison, Lindsay J.; Easterling, Michael L.; Paša-Tolić, Ljiljana; Wysocki, Vicki H.

    2017-01-03

    Mass spectrometry continues to develop as a valuable tool in the analysis of proteins and protein complexes. In protein complex mass spectrometry studies, surface-induced dissociation (SID) has been successfully applied in quadrupole time-of-flight (Q-TOF) instruments. SID provides structural information on non-covalent protein complexes that is complementary to other techniques. However, the mass resolution of Q-TOF instruments can limit the information that can be obtained for protein complexes by SID. Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) provides ultrahigh resolution and ultrahigh mass accuracy measurements. In this study, an SID device was designed and successfully installed in a hybrid FT-ICR instrument in place of the standard gas collision cell. The SID-FT-ICR platform has been tested with several protein complex systems (homooligomers, a heterooligomer, and a protein-ligand complex, ranging from 53 kDa to 85 kDa), and the results are consistent with data previously acquired on Q-TOF platforms, matching predictions from known protein interface information. SID fragments with the same m/z but different charge states are well-resolved based on distinct spacing between adjacent isotope peaks, and the addition of metal cations and ligands can also be isotopically resolved with the ultrahigh mass resolution available in FT-ICR.

  13. Changes in orexinergic immunoreactivity of the piglet hypothalamus and pons after exposure to chronic postnatal nicotine and intermittent hypercapnic hypoxia.

    Science.gov (United States)

    Hunt, Nicholas J; Russell, Benjamin; Du, Man K; Waters, Karen A; Machaalani, Rita

    2016-06-01

    We recently showed that orexin expression in sudden infant death syndrome (SIDS) infants was reduced by 21% in the hypothalamus and by 40-50% in the pons as compared with controls. Orexin maintains wakefulness/sleeping states, arousal, and rapid eye movement sleep, abnormalities of which have been reported in SIDS. This study examined the effects of two prominent risk factors for SIDS, intermittent hypercapnic hypoxia (IHH) (prone-sleeping) and chronic nicotine exposure (cigarette-smoking), on orexin A (OxA) and orexin B (OxB) expression in piglets. Piglets were randomly assigned to five groups: saline control (n = 7), air control (n = 7), nicotine [2 mg/kg per day (14 days)] (n = 7), IHH (6 min of 7% O2 /8% CO2 alternating with 6-min periods of breathing air, for four cycles) (n = 7), and the combination of nicotine and IHH (N + IHH) (n = 7). OxA/OxB expression was quantified in the central tuberal hypothalamus [dorsal medial hypothalamus (DMH), perifornical area (PeF), and lateral hypothalamus], and the dorsal raphe, locus coeruleus of the pons. Nicotine and N + IHH exposures significantly increased: (i) orexin expression in the hypothalamus and pons; and (ii) the total number of neurons in the DMH and PeF. IHH decreased orexin expression in the hypothalamus and pons without changing neuronal numbers. Linear relationships existed between the percentage of orexin-positive neurons and the area of pontine orexin immunoreactivity of control and exposure piglets. These results demonstrate that postnatal nicotine exposure increases the proportion of orexin-positive neurons in the hypothalamus and fibre expression in the pons, and that IHH exposure does not prevent the nicotine-induced increase. Thus, although both nicotine and IHH are risk factors for SIDS, it appears they have opposing effects on OxA and OxB expression, with the IHH exposure closely mimicking what we recently found in SIDS. © 2016 Federation of European Neuroscience Societies and John

  14. The author training manual develop marketable ideas, craft books that sell, become the author publishers want, and self-publish effectively

    CERN Document Server

    Amir, Nina

    2014-01-01

    Anyone can publish a book and become an ""author,"" but if you want to become a successful author with a profitable publishing career, you need a clear, step-by-step guide to help you develop book ideas that sell. In The Author Training Manual, expert editor and book coach Nina Amir reveals the exact process successful authors have used to create business plans and proposals for their books and teaches you how to view your ideas through the eyes of acquisitions editors and literary agents. Whether you write fiction or nonfiction, plan to traditionally publish or self-publish, The Author Tra

  15. Radiographic aspects of excessive administration of vitamin A-D3- and E in calf [Emilia Romagna - musculoskeletal diseases

    International Nuclear Information System (INIS)

    Gentile, A.; Cipone, M.; Testoni, S.; Gandini, G.; Trenti, F.

    1997-01-01

    Knee and elbow radiographs were obtained from three calves treated with excessive dosages of vitamins A (1,000,000 IU s.i.d.), D3 (150,000 IU s.i.d.) and E (100 mg s.i.d.) for three months. The radiographs showed the presence of radiopaque strip located on the metaphyseal cement lines of the femur and radius. This gave evidence for an anticipated closure of the cement lines of these bones [it

  16. Starvation induces phenotypic diversification and convergent evolution in Vibrio vulnificus.

    Directory of Open Access Journals (Sweden)

    Hwajiun Chen

    Full Text Available Starvation is a common stress experienced by bacteria living in natural environments and the ability to adapt to and survive intense stress is of paramount importance for any bacterial population. A series of starvation experiments were conducted using V. vulnificus 93U204 in phosphate-buffered saline and seawater. The starved population entered the death phase during the first week and approximately 1% of cells survived. After that the population entered a long-term stationary phase, and could survive for years. Starvation-induced diversification (SID of phenotypes was observed in starved populations and phenotypic variants (PVs appeared in less than 8 days. The cell density, rather than the population size, had a major effect on the extent of SID. SID was also observed in strain YJ016, where it evolved at a faster pace. PVs appeared to emerge in a fixed order: PV with reduced motility, PV with reduced proteolytic activity, and PV with reduced hemolytic activity. All of the tested PVs had growth advantages in the stationary phase phenotypes and increased fitness compared with 93U204 cells in co-culture competition experiments, which indicates that they had adapted to starvation. We also found that SID occurred in natural seawater with a salinity of 1%-3%, so this mechanism may facilitate bacterial adaptation in natural environments.

  17. FIRST TIME ONLINE LEARNERS’ PERCEPTIONS OF SUPPORT SERVICES PROVIDED

    Directory of Open Access Journals (Sweden)

    Stephanie HUNTE

    2012-04-01

    Full Text Available The number of online continuous education and training initiatives continues to increase in Caribbean Small Island Developing States (SIDS and by extension, the number of adult learners who are unfamiliar with the peculiarities of the online teaching and learning environment. The extent to which these learners can derive maximum benefit from these initiatives depends on the rate at which they can adapt to the new circumstances and, as a result, function effectively in this type of teaching and learning environment. To this end, while supporting learners is recognized as a critical success factor little has been explored or documented specific to the Caribbean-SIDS context. The purpose of this study therefore was to describe the support services provided first time online learners in the context of Caribbean-SIDS and examine what if any benefit learners derived from them through their perceptions of these services. The findings reveal that participants’ overall perception of the support services was high. They also reveal that although participants’ awareness of ongoing support services was variable, their rating of the need for and importance of this type of support was also high. The findings suggest that providing support for first time online learners in the context of Caribbean SIDS positively impacts their performance in the online teaching and learning environment.

  18. Job Authority and Breast Cancer.

    Science.gov (United States)

    Pudrovska, Tetyana

    2013-01-01

    Using the 1957-2011 data from the Wisconsin Longitudinal Study, I integrate the gender relations theory, a life course perspective, and a biosocial stress perspective to explore the effect of women's job authority in 1975 (at age 36) and 1993 (at age 54) on breast cancer incidence up to 2011. Findings indicate that women with the authority to hire, fire, and influence others' pay had a significantly higher risk of a breast cancer diagnosis over the next 30 years compared to housewives and employed women with no job authority. Because job authority conferred the highest risk of breast cancer for women who also spent more hours dealing with people at work in 1975, I suggest that the assertion of job authority by women in the 1970s involved stressful interpersonal experiences, such as social isolation and negative social interactions, that may have increased the risk of breast cancer via prolonged dysregulation of the glucocorticoid system and exposure of breast tissue to the adverse effects of chronically elevated cortisol. This study contributes to sociology by emphasizing gendered biosocial pathways through which women's occupational experiences become embodied and drive forward physiological repercussions.

  19. Effects of Students' Participation in Authoring of Multimedia Materials on Student Acquisition of Vocabulary.

    Science.gov (United States)

    Nikolova, Ofelia R.

    2002-01-01

    Investigated the effects on vocabulary acquisition of student participation in authoring a multimedia institutional module. Sixty-two subjects were randomly assigned to two groups, and each group was randomly assigned to one of two treatments. Showed evidence that students learn vocabulary significantly better when they participate in the creation…

  20. Dicty_cDB: SSF684 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available equence iiimiiiilkk***ncn*nkenkssw**nici*rsmmstliflvfrt*sid*tfttnttt tnttttr*rft*sgsst*cc*wfiiyfn*ihcwlikrsi...***ncn*nkenkssw**nici*rsmmstliflvfrt*sid*tfttnttt tnttttr*rft*sgsst*cc*wfiiyfn*ihcwlikrsiicvcpfnii*pyinwisli

  1. TREATMENT SUCCESS IN THREE ANDEAN BEARS (TREMARCTOS ORNATUS) WITH ALOPECIA SYNDROME USING OCLACITINIB MALEATE (APOQUEL®).

    Science.gov (United States)

    Drake, Gabby J; Nuttall, Tim; López, Javier; Magnone, William; Leclerc, Antoine; Potier, Romain; Lécu, Alexis; Guézénec, Maëlle; Kolter, Lydia; Nicolau, Amélie; Lemberger, Karin; Pin, Didier; Cosgrove, Sallie B

    2017-09-01

    Andean bear (Tremarctos ornatus) alopecia syndrome (ABAS) commonly affects captive bears, particularly sexually mature females. ABAS is characterized by bilaterally symmetrical predominantly flank alopecia with or without profound pruritus and secondary bacterial and Malassezia infections. There is no effective treatment and severely affected bears have been euthanized. This paper describes the successful management of ABAS in three female Andean bears. Skin biopsies and cytology revealed a mixed dermal inflammatory infiltrate, alopecia, hyperkeratosis, and Malassezia dermatitis. Allergen specific serology was positive for environmental allergens in one case. Hematology, serum biochemistry, and thyroid and adrenal function were normal in all cases. There was no consistent response to novel diet trials, antifungals, antihistamines, allergen specific immunotherapy, or topical antimicrobials. There was a partial response to ciclosporin (Atopica® cat, Novartis Animal Health; 5 mg/kg po, sid) in one case and oral glucocorticoids in all cases (dexamethasone sodium phosphate, [Colvasone 0.2%, Norbrook], 0.15 mg/kg po, sid or prednisolone [Deltacortene, Bruno Farmaceutici, and Megasolone 20, Coophavet], 0.3-1.2 mg/kg po, sid), but treatment was withdrawn following adverse effects. Treatment with oclacitinib maleate (Apoquel®, Zoetis; 0.46-0.5 mg/kg po, bid) resulted in rapid and complete resolution of the pruritus with subsequent improvement in demeanor and fur regrowth. After 5 mo, the bears were almost fully furred and off all other medication. Treatment was tapered to the lowest dose that prevented relapse of the pruritus (0.23-0.4 mg/kg po, sid). No adverse effects have been noted. ABAS is usually an intractable condition, and, to our knowledge, oclacitinib is the first treatment shown to result in sustained clinical improvement. Further studies on the etiology of ABAS, and on efficacy and long-term safety of oclacitinib are needed.

  2. Security Investigation Database (SID)

    Data.gov (United States)

    US Agency for International Development — Security Investigation & Personnel Security Clearance - COTS personnel security application in a USAID virtualized environement that can support USAID's business...

  3. Characteristics of Effective Collaboration in Response to Diversified Transportation Planning Authority

    Directory of Open Access Journals (Sweden)

    John S. Miller

    2011-01-01

    Full Text Available Advantages of decentralized transportation planning responsibilities may include reduced project delivery cost, the integration of comprehensive long-range planning with regional land use, and greater accountability regarding local concerns. Yet disadvantages may include a tendency for operations to dominate longer-term planning, inconsistent operational standards, and difficulty in achieving network benefits, since some transportation links may provide benefits to the entire system but not to the immediate area where the link is located. To surmount these challenges in a decentralized environment, agencies need to cooperate effectively. Characteristics of effective collaboration include (1 experienced personnel, (2 credibility of the deciding entity, (3 transparency of decision-making processes, (4 an authority with sufficient power and/or funding to encourage implementation of key initiatives, (5 clear incentives for cooperation, and, of special importance given limited resources, and (6 an ability to evaluate tradeoffs. An access management case study demonstrates how agencies may use these characteristics to advance challenging projects in a decentralized environment.

  4. Supplier-induced demand: re-examining identification and misspecification in cross-sectional analysis.

    Science.gov (United States)

    Peacock, Stuart J; Richardson, Jeffrey R J

    2007-09-01

    This paper re-examines criticisms of cross-sectional methods used to test for supplier-induced demand (SID) and re-evaluates the empirical evidence using data from Australian medical services. Cross-sectional studies of SID have been criticised on two grounds. First, and most important, the inclusion of the doctor supply in the demand equation leads to an identification problem. This criticism is shown to be invalid, as the doctor supply variable is stochastic and depends upon a variety of other variables including the desirability of the location. Second, cross-sectional studies of SID fail diagnostic tests and produce artefactual findings due to model misspecification. Contrary to this, the re-evaluation of cross-sectional Australian data indicate that demand equations that do not include the doctor supply are misspecified. Empirical evidence from the re-evaluation of Australian medical services data supports the notion of SID. Demand and supply equations are well specified and have very good explanatory power. The demand equation is identified and the desirability of a location is an important predictor of the doctor supply. Results show an average price elasticity of demand of 0.22 and an average elasticity of demand with respect to the doctor supply of 0.46, with the impact of SID becoming stronger as the doctor supply rises. The conclusion we draw from this paper is that two of the main criticisms of the empirical evidence supporting the SID hypothesis have been inappropriately levelled at the methods used. More importantly, SID provides a satisfactory, and robust, explanation of the empirical data on the demand for medical services in Australia.

  5. 41 CFR 102-75.315 - Are appraisers authorized to consider the effect of historic covenants on the fair market value?

    Science.gov (United States)

    2010-07-01

    ... authorized to consider the effect of historic covenants on the fair market value? 102-75.315 Section 102-75... market value? Yes, appraisers are authorized to consider the effect of historic covenants on the fair market value, if the property is in or eligible for listing in the National Register of Historic Places. ...

  6. Effects of anchoring and arc structure on the control authority of a rail plasma actuator

    International Nuclear Information System (INIS)

    Choi, Young-Joon; Gray, Miles; Sirohi, Jayant; Raja, Laxminarayan L

    2017-01-01

    Experiments were conducted on a rail plasma actuator (RailPAc) with different electrode cross sections (rails or rods) to assess methods to improve the actuation authority, defined as the impulse generated for a given electrical input. The arc was characterized with electrical measurements and high-speed images, while impulse measurements quantified the actuation authority. A RailPAc power supply capable of delivering  ∼1 kA of current at  ∼100 V was connected to rod electrodes (free-floating with circular cross-section) and rail electrodes (flush-mounted in a flat plate with rectangular cross-section). High-speed images show that the rail electrodes cause the arc to anchor itself to the anode electrode and transit in discrete jumps, while rod electrodes permit the arc to transit smoothly without anchoring. The impulse measurements reveal that the anchoring reduces the actuation authority by  ∼21% compared to a smooth transit, and the effect of anchoring can be suppressed by reducing the gap between the rails to 2 mm. The study further demonstrates that if a smooth transit is achieved, the control authority can be increased with a larger gap and larger arc current. In conclusion, the actuation authority of a RailPAc can be maximized by carefully choosing a gap width that prevents anchoring. Further study is warranted to increase the RailPAc actuation authority by introducing multiple turns of wires beneath the RailPAc to augment the induced magnetic field. (paper)

  7. 75 FR 12123 - Federal Motor Vehicle Safety Standards; Side Impact Protection; Fuel System Integrity; Electric...

    Science.gov (United States)

    2010-03-15

    ... Restraint Position for the SID-IIs iii. Adjustable Seat Belt Shoulder Anchor iv. Adjustable Steering Wheels... Definitions 2. Test Dummy Set-Up i. SID-IIs A. Hip Point Specification B. Knee and Ankle Spacing C. Pelvic...

  8. 77 FR 37412 - Delegation of Authority

    Science.gov (United States)

    2012-06-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Community Living Delegation of Authority Effective immediately, I hereby delegate to the individual serving as the Administrator for the... of the Social Security Act, 42 U.S.C. 1397k. This authority may be redelegated. This delegation...

  9. Regulatory authority information system RAIS

    International Nuclear Information System (INIS)

    Ortiz, P.; Mrabit, K.; Miaw, S.

    2000-01-01

    In this lecture the principles of the regulatory authority information system (RAIS) are presented. RAIS is a tool currently being developed by the IAEA for the Regulatory Authorities. It is a part of a set of supporting actions designed to assist member states in achieving the objectives of the Model project on radiation and waste safety infrastructure. RAIS is a tool that provides the management of the Regulatory Authority with the key information needed for the planning and implementation of activities and to ensure confidence that resources are optimally used. The RAIS contains five modules: Inventory of installations and radiation sources; Authorization process; Inspection and follow-up actions; Information on personal dosimetry; Assessment of effectiveness by means of performance indicators

  10. Antenatal smoking and substance-misuse, infant and newborn response to hypoxia.

    Science.gov (United States)

    Ali, Kamal; Rosser, Thomas; Bhat, Ravindra; Wolff, Kim; Hannam, Simon; Rafferty, Gerrard F; Greenough, Anne

    2017-05-01

    To determine at the peak age for sudden infant death syndrome (SIDS) the ventilatory response to hypoxia of infants whose mothers substance misused in pregnancy (SM infants), or smoked during pregnancy (S mothers) and controls whose mothers neither substance misused or smoked. In addition, we compared the ventilatory response to hypoxia during the neonatal period and peak age of SIDS. Infants of S or SM mothers compared to control infants would have a poorer ventilatory response to hypoxia at the peak age of SIDS. Prospective, observational study. Twelve S; 12 SM and 11 control infants were assessed at 6-12 weeks of age and in the neonatal period. Changes in minute volume, oxygen saturation, heart rate, and end tidal carbon dioxide levels on switching from breathing room air to 15% oxygen were assessed. Maternal and infant urine samples were tested for cotinine, cannabinoids, opiates, amphetamines, methadone, cocaine, and benzodiazepines. The S and SM infants had a greater decline in minute volume (P = 0.037, P = 0.016, respectively) and oxygen saturation (P = 0.031) compared to controls. In all groups, the magnitude of decline in minute volume in response to hypoxia was higher in the neonatal period compared to at 6-12 weeks (P ventilatory decline was more marked in the neonatal period compared to the peak age for SIDS indicating a maturational effect. Pediatr Pulmonol. 2017;52:650-655. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  11. Oligosaccharides are a key factor in prediction of amino acid digestibility in soybean meal of different origins when fed to growing pigs

    Science.gov (United States)

    Li, Zhongchao; Wang, Qiuyun; Xie, Fei; Liu, Dewen; Li, Yakui; Lyu, Zhiqian; Lai, Changhua

    2017-01-01

    Objective The objective of this experiment was to determine apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of crude protein (CP) and amino acid (AA) in 15 sources of soybean meal (SBM) produced from soybeans from different countries and subsequently to establish equations for predicting the AID and SID in SBM based on their chemical composition. Methods Eighteen barrows (57.9±6.1 kg) fitted with a simple T-cannula were allotted into three 6×6 Latin square designs. Each period comprised a 6-d adaption period followed by a 2-d collection of ileal digesta. The 15 test diets included SBM as a sole source of AA in the diet. Another nitrogen-free diet was used to measure basal endogenous losses of CP and AA. Chromic oxide (0.3%) was used as an inert marker in each diet. Results The AID of lysine in SBM from China and USA tended to be greater than in SBM from Brazil (p<0.10). The SID of valine and proline in SBM from China was greater than in SBM from Brazil (p<0.05). The SID of lysine, threonine, cysteine and glycine in SBM from China tended to be greater than in SBM from Brazil (p<0.10). From a stepwise regression analysis, a series of AID and SID prediction equations were generated. The best fit equations for lysine in SBM were: AID lysine = 1.16 sucrose−1.81 raffinose+82.10 (R2 = 0.69, p<0.01) and SID lysine = 1.14 sucrose−1.93 raffinose−0.99 ether extract (EE)+85.26 (R2 = 0.77, p<0.01). Conclusion It was concluded that under the conditions of this experiment, the oligosaccharides (such as sucrose and raffinose) can be used to predict the AID and SID of AA in SBM with reasonable accuracy. PMID:28427255

  12. Serotonin-related FEV gene variant in the sudden infant death syndrome is a common polymorphism in the African-American population.

    Science.gov (United States)

    Broadbelt, Kevin G; Barger, Melissa A; Paterson, David S; Holm, Ingrid A; Haas, Elisabeth A; Krous, Henry F; Kinney, Hannah C; Markianos, Kyriacos; Beggs, Alan H

    2009-12-01

    An important subset of the sudden infant death syndrome (SIDS) is associated with multiple serotonergic (5-HT) abnormalities in regions of the medulla oblongata. The mouse ortholog of the fifth Ewing variant gene (FEV) is critical for 5-HT neuronal development. A putatively rare intronic variant [IVS2-191_190insA, here referred to as c.128-(191_192)dupA] has been reported as a SIDS-associated mutation in an African-American population. We tested this association in an independent dataset: 137 autopsied cases (78 SIDS, 59 controls) and an additional 296 control DNA samples from Coriell Cell Repositories. In addition to the c.128-(191_192)dupA variant, we observed an associated single-base deletion [c.128-(301-306)delG] in a subset of the samples. Neither of the two FEV variants showed significant association with SIDS in either the African-American subgroup or the overall cohort. Although we found a significant association of c.128-(191_192)dupA with SIDS when San Diego Hispanic SIDS cases were compared with San Diego Hispanic controls plus Mexican controls (p = 0.04), this became nonsignificant after multiple testing correction. Among Coriell controls, 33 of 99 (33%) African-American and 0 of 197 (0%) of the remaining controls carry the polymorphism (c.128-(191_192)dupA). The polymorphism seems to be a common, likely nonpathogenic, variant in the African-American population.

  13. 77 FR 56243 - Options Price Reporting Authority; Notice of Filing and Immediate Effectiveness of Proposed...

    Science.gov (United States)

    2012-09-12

    ... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-67791; File No. SR-OPRA-2012-05] Options Price Reporting Authority; Notice of Filing and Immediate Effectiveness of Proposed Amendment to the Plan for...'') \\1\\ and Rule 608 thereunder,\\2\\ notice is hereby given that on August 27, 2012, the Options Price...

  14. Novel Resuscitation from Lethal Hemorrhage - Suspended Animation for Delayed Resuscitation

    Science.gov (United States)

    2002-09-01

    a temperatura alvo emn doentes fora do hospital ou jA intemados permanece urn desaflo. Este estudo procurou testar a exequibilidade do arrefecimento...Durante a normotensiio espontfinea, o arrefecirniento veno-venoso forniecia sangue A veia cava a uma temperatura de 6.2 ’CC desvio padr~o (SID 1.4) e...dirninuiu a temperatura da membrana timpfinica (fly) de 37.5 para 34.0’C aos 5 min (SID 0.7) e para os; 32 ’C aos 7.9 min (SID 1.3). 0 arrefecimento da

  15. The role of fluorescent pseudo monad's siderophore on Zn absorption in wheat by using 65Zn

    International Nuclear Information System (INIS)

    Rasouli Sadaghiani, M. H.; Malakouti, M. J.; Khavazi, K.; Ghannadi Maragheh, M.

    2008-01-01

    Zn to shoots, particularly in efficient Tabasi genotype. Siderophore effectiveness in Zn availability decreased in the order of SidDFOB> Sid-P. putida>Sid-P. fluorescence> Sid-P. aeruginosa. Due to the availability of P. putida in absorbing Zn, the siderophores of this group of bacteria can be named as zincophore

  16. Spectral band discrimination for species observed from hyperspectral remote sensing

    CSIR Research Space (South Africa)

    Dudeni, N

    2009-08-01

    Full Text Available across the spectrum. Spectral matching is often achieved by means of matching algorithms such as the Spectral Angle Mapper (SAM), Spectral information divergence (SID) and mixed measures of SAM and SID using either the tangent or the sine trigonometric...

  17. Energy and lysine requirements and balances of sows during transition and lactation: A factorial approach

    DEFF Research Database (Denmark)

    Feyera, Takele; Theil, Peter Kappel

    2017-01-01

    components (including uterus wall, placenta and membrane fluids) and maintenance were estimated. It was estimated that maintenance, additional heat loss, colostrum production, fetal growth, mammary growth and uterine components accounted for 66.8%, 19.3%, 7.2%, 5.0%, 1.3% and 0.5% of total ME requirements......, respectively, in the last 12 days of gestation. Oxidation/transamination, fetal growth, mammary growth, colostrum production, maintenance and uterine components were estimated to account for 29.5%, 22.7%, 16.8%, 16.1%, 10.4% and 4.5% of total SID lysine requirements, respectively, in the last 12 days...... of gestation. After parturition, ME and SID lysine requirements increased daily until peak lactation (day 17). At peak lactation, 95% and 72% of total required SID lysine and ME, respectively, were associated with milk production (including oxidation). Relative to day 104 of gestation, ME and SID lysine...

  18. Sudden unexpected death in infancy in Denmark

    DEFF Research Database (Denmark)

    Winkel, Bo Gregers; Holst, Anders Gaarsdal; Theilade, Juliane

    2011-01-01

    Abstract Background. Incidence of sudden unexpected death in infancy (SUDI) and sudden infant death syndrome (SIDS) differs among studies and non-autopsied cases are difficult to assess. Objectives. To investigate causes of sudden death in infancy in a nationwide setting. Validate the use...... of the ICD-10 code for SIDS (R95) in the Danish Cause of Death registry. Design. A retrospective analysis of all infant deaths (death certificates and autopsy reports were read. Results. We identified 192 SUDI cases (10% of total deaths, 0.42 per 1000 births......) with autopsy performed in 87% of cases. In total, 49% of autopsied SUDI cases were defined as SIDS (5% of all deaths, 0.22 per 1000 births); Cardiac cause of death was denoted in 24% of cases. The Danish Cause of Death Registry misclassified 30% of SIDS cases. Conclusions. A large proportion of infant deaths...

  19. Heat stress and sudden infant death syndrome--stress gene expression after exposure to moderate heat stress

    DEFF Research Database (Denmark)

    Rohde, Marianne Cathrine; Corydon, Thomas Juhl; Hansen, Jakob

    2013-01-01

    The aim of the present study was to investigate stress gene expression in cultured primary fibroblasts established from Achilles tendons collected during autopsies from sudden infant death syndrome (SIDS) cases, and age-matched controls (infants dying in a traumatic event). Expression of 4 stress...... responsive genes, HSPA1B, HSPD1, HMOX1, and SOD2, was studied by quantitative reverse transcriptase PCR analysis of RNA purified from cells cultured under standard or various thermal stress conditions. The expression of all 4 genes was highly influenced by thermal stress in both SIDS and control cells. High...... interpersonal variance found in the SIDS group indicated that they represented a more heterogeneous group than controls. The SIDS group responded to thermal stress with a higher expression of the HSPA1B and HSPD1 genes compared to the control group, whereas no significant difference was observed...

  20. Quantifying the effect of editor-author relations on manuscript handling times.

    Science.gov (United States)

    Sarigöl, Emre; Garcia, David; Scholtes, Ingo; Schweitzer, Frank

    2017-01-01

    In this article we study to what extent the academic peer review process is influenced by social relations between the authors of a manuscript and the editor handling the manuscript. Taking the open access journal PlosOne as a case study, our analysis is based on a data set of more than 100,000 articles published between 2007 and 2015. Using available data on handling editor, submission and acceptance time of manuscripts, we study the question whether co-authorship relations between authors and the handling editor affect the manuscript handling time , i.e. the time taken between the submission and acceptance of a manuscript. Our analysis reveals (1) that editors handle papers co-authored by previous collaborators significantly more often than expected at random, and (2) that such prior co-author relations are significantly related to faster manuscript handling. Addressing the question whether these shorter manuscript handling times can be explained by the quality of publications, we study the number of citations and downloads which accepted papers eventually accumulate. Moreover, we consider the influence of additional (social) factors, such as the editor's experience, the topical similarity between authors and editors, as well as reciprocal citation relations between authors and editors. Our findings show that, even when correcting for other factors like time, experience, and performance, prior co-authorship relations have a large and significant influence on manuscript handling times, speeding up the editorial decision on average by 19 days.

  1. Disparities in Maternal Child and Health Outcomes Attributable to Prenatal Tobacco Use.

    Science.gov (United States)

    Mohlman, Mary Katherine; Levy, David T

    2016-03-01

    Previous estimates of smoking-attributable adverse outcomes, such as preterm births (PTBs), low birth weight (LBW) and Sudden Infant Death Syndrome (SIDs) generally do not address disparities by maternal age, racial/ethnic group or socioeconomic status (SES). This study develops estimates of smoking-attributable PTB, LBW and SIDS for the US by age, SES and racial/ethnic groupings. Data on the number of births and the prevalence of PTB, LBW and SIDS were used to develop the number of outcomes by age, race/ethnicity, and SES. The prevalence of prenatal smoking by age, race/ethnic and education and the relative risk of outcomes for smokers were used to calculate smoking-attributable fractions of outcomes. Prenatal smoking among ages 15-24 is above 12 %, with 20-24 year olds representing at least 35 % of PTB, LBW SIDS cases. Women with a high school education or less represented more than 50 % of PTB and LBW births, and 44 % of SIDS cases. While non-Hispanic Whites had the majority of smoking-attributable outcomes, non-Hispanic Blacks represented a disproportionately high percentage of PTBs (18 %), LBW births (22 %), and SIDS cases (13 %). Reducing prenatal smoking has the potential to reduce adverse birth outcomes and costs with long-term implications, especially among the young, non-Hispanic Blacks and those of lower SES. Stricter tobacco control policies, especially higher cigarette taxes, higher minimum purchase ages for tobacco and improved cessation interventions can help reduce disparities and the cost to insurers, especially public costs through Medicaid.

  2. Achieving universal health coverage in small island states: could importing health services provide a solution?

    Science.gov (United States)

    Walls, Helen; Smith, Richard

    2018-01-01

    Background Universal health coverage (UHC) is difficult to achieve in settings short of medicines, health workers and health facilities. These characteristics define the majority of the small island developing states (SIDS), where population size negates the benefits of economies of scale. One option to alleviate this constraint is to import health services, rather than focus on domestic production. This paper provides empirical analysis of the potential impact of this option. Methods Analysis was based on publicly accessible data for 14 SIDS, covering health-related travel and health indicators for the period 2003–2013, together with in-depth review of medical travel schemes for the two highest importing SIDS—the Maldives and Tuvalu. Findings Medical travel from SIDS is accelerating. The SIDS studied generally lacked health infrastructure and technologies, and the majority of them had lower than the recommended number of physicians in a country, which limits their capacity for achieving UHC. Tuvalu and the Maldives were the highest importers of healthcare and notably have public schemes that facilitate medical travel and help lower the out-of-pocket expenditure on medical travel. Although different in approach, design and performance, the medical travel schemes in Tuvalu and the Maldives are both examples of measures used to increase access to health services that cannot feasibly be provided in SIDS. Interpretation Our findings suggest that importing health services (through schemes to facilitate medical travel) is a potential mechanism to help achieve universal healthcare for SIDS but requires due diligence over cost, equity and quality control. PMID:29527349

  3. Conformity of LINAC-Based Stereotactic Radiosurgery Using Dynamic Conformal Arcs and Micro-Multileaf Collimator

    International Nuclear Information System (INIS)

    Hazard, Lisa J.; Wang, Brian; Skidmore, Thomas B.; Chern, Shyh-Shi; Salter, Bill J.; Jensen, Randy L.; Shrieve, Dennis C.

    2009-01-01

    Purpose: To assess the conformity of dynamic conformal arc linear accelerator-based stereotactic radiosurgery and to describe a standardized method of isodose surface (IDS) selection. Methods and Materials: In 174 targets, the conformity index (CI) at the prescription IDS used for treatment was calculated as CI = (PIV/PVTV)/(PVTV/TV), where TV is the target volume, PIV (prescription isodose volume) is the total volume encompassed by the prescription IDS, and PVTV is the TV encompassed by the IDS. In addition, a 'standardized' prescription IDS (sIDS) was chosen according to the following criteria: 95% of the TV was encompassed by the PIV and 99% of TV was covered by 95% of the prescription dose. The CIs at the sIDS were also calculated. Results: The median CI at the prescription IDS and sIDS was 1.63 and 1.47, respectively (p < 0.001). In 132 of 174 cases, the volume of normal tissue in the PIV was reduced by the prescription to the sIDS compared with the prescription IDS, in 20 cases it remained unchanged, and in 22 cases it was increased. Conclusion: The CIs obtained with linear accelerator-based stereotactic radiosurgery are comparable to those previously reported for gamma knife stereotactic radiosurgery. Using a uniform method to select the sIDS, adequate target coverage was usually achievable with prescription to an IDS greater than that chosen by the treating physician (prescription IDS), providing sparing of normal tissue. Thus, the sIDS might aid physicians in identifying a prescription IDS that balances coverage and conformity

  4. Challenging authority during a life-threatening crisis: the effect of operating theatre hierarchy.

    Science.gov (United States)

    Sydor, D T; Bould, M D; Naik, V N; Burjorjee, J; Arzola, C; Hayter, M; Friedman, Z

    2013-03-01

    Effective operating theatre (OT) communication is important for team function and patient safety. Status asymmetry between team members may contribute to communication breakdown and threaten patient safety. We investigated how hierarchy in the OT team influences an anaesthesia trainee's ability to challenge an unethical decision by a consultant anaesthetist in a simulated crisis scenario. We prospectively randomized 49 postgraduate year (PGY) 2-5 anaesthesia trainees at two academic hospitals to participate in a videotaped simulated crisis scenario with a simulated OT team practicing either a hierarchical team structure (Group H) or a non-hierarchical team structure (Group NH). The scenario allowed trainees several opportunities to challenge their consultant anaesthetist when administering blood to a Jehovah's Witness. Three independent, blinded raters scored the performances using a modified advocacy-inquiry score (AIS). The primary outcome was the comparison of the best-response AIS between Groups H vs NH. Secondary outcomes included the comparison of best AIS by PGY and the percentage in each group that checked and administered blood. The AIS did not differ between the groups (P=0.832) but significantly improved from PGY2 to PGY5 (P=0.026). The rates of checking blood (92% vs 76%, P=0.082) and administering blood (62% vs 57%, P=0.721) were high in both groups but not significantly different between the groups. This study did not show a significant effect of OT team hierarchical structure on trainee's ability to challenge authority; however, the results are concerning. The challenges were suboptimal in quality and there was an alarming high rate of blood checking and administration in both groups. This may reflect lack of training in appropriately and effectively challenging authority within the formal curriculum with implications for patient safety.

  5. Climate Change | Page 17 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Home · Agriculture and Environment. Climate Change. Language English. Read more about CapaSIDS : Capacity Building and Knowledge on Sustainable Responses to Climate Change in Small Island States. Language English. Read more about CapaSIDS : renforcement des capacités et production de connaissances ...

  6. 77 FR 69485 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2012-11-19

    ... health priorities. Between 1990 and 2001, the rate of SIDS in the U.S. decreased from 1.3 per 1,000 live births to 0.56 deaths per 1,000 live births. The 50% decline in SIDS is attributed to the success of the...

  7. Amino acid utilization and body composition of growing pigs fed processed soybean meal or rapeseed meal with or without amino acid supplementation.

    Science.gov (United States)

    Hulshof, T G; van der Poel, A F B; Hendriks, W H; Bikker, P

    2017-07-01

    Feed ingredients used in swine diets are often processed to improve nutritional value. However, (over-)processing may result in chemical reactions with amino acids (AAs) that decrease their ileal digestibility. This study aimed to determine effects of (over-)processing of soybean meal (SBM) and rapeseed meal (RSM) on post-absorptive utilization of ileal digestible AAs for retention and on body AA composition of growing pigs. Soybean meal and RSM were processed by secondary toasting in the presence of lignosulfonate to obtain processed soybean meal (pSBM) and processed rapeseed meal (pRSM). Four diets contained SBM, pSBM, RSM or pRSM as sole protein source. Two additional diets contained pSBM or pRSM and were supplemented with crystalline AA to similar standardized ileal digestible (SID) AA level as the SBM or RSM diet. These diets were used to verify that processing affected AA retention by affecting ileal AA digestibility rather than post-absorptive AA utilization. The SID AA levels of the protein sources were determined in a previous study. In total, 59 pigs were used (initial BW of 15.6±0.7 kg) of which five were used to determine initial body composition at the start of the experiment. In total, 54 pigs were fed one of six experimental diets and were slaughtered at a BW of 40 kg. The organ fraction (i.e. empty organs plus blood) and carcass were analyzed separately for N and AA content. Post-absorptive AA utilization was calculated from AA retention and SID AA intake. An interaction between diet type, comprising effects of processing and supplementing crystalline AA, and protein source was observed for CP content in the organ fraction, carcass and empty body and for nutrient retention. Processing reduced CP content and nutrient retention more for SBM than for RSM. Moreover, processing reduced (P<0.001) the lysine content in the organ fraction for both protein sources. Supplementing crystalline AA ameliorated the effect of processing on these variables. Thus

  8. Strong ion difference in urine: new perspectives in acid-base assessment.

    OpenAIRE

    Gattinoni, L.; Carlesso, E.; Cadringher, P.; Caironi, P.

    2006-01-01

    The plasmatic strong ion difference (SID) is the difference between positively and negatively charged strong ions. At pH 7.4, temperature 37°C and partial carbon dioxide tension 40 mmHg, the ideal value of SID is 42 mEq/l. The buffer base is the sum of negatively charged weak acids ([HCO3 -], [A-], [H2PO4 -]) and its normal value is 42 mEq/l. According to the law of electroneutrality, the amount of positive and negative charges must be equal, and therefore the SID value is equal to the buffer...

  9. Energy policy, aid, and the development of renewable energy resources in Small Island Developing States

    International Nuclear Information System (INIS)

    Dornan, Matthew; Shah, Kalim U.

    2016-01-01

    Small Island Developing States (SIDS) have established ambitious renewable energy targets. The promotion of renewable energy has been motivated by several factors: a desire to lessen dependence on fossil fuels, to attract development assistance in the energy sector, and to strengthen the position of SIDS in climate change negotiations. Here we explore the interplay between the role of aid and energy policy in the development of renewable energy resources in SIDS. We find that the importance of development assistance has implications for the sustainability of renewable energy development, given that funding is not always accompanied by necessary energy policy reforms. We also identify energy efficiency and access to modern energy services as having received insufficient attention in the establishment and structure of renewable energy targets in SIDS, and argue that this is problematic due to the strong economic case for such investments. - Highlights: • SIDS have established the world's most ambitious renewable energy targets. • These are motivated by fossil fuel dependence and climate change vulnerability. • Aid dependence has influenced the ambition of renewable energy targets. • Energy efficiency and energy access have received insufficient attention. • Domestic policy reforms necessary for the achievement of targets has been limited.

  10. Surface Ionization and Soft Landing Techniques in Mass Spectrometry

    International Nuclear Information System (INIS)

    Futrell, Jean H.; Laskin, Julia

    2010-01-01

    The advent of soft ionization techniques, notably electrospray and laser desorption ionization methods, has extended mass spectrometric methods to large molecules and molecular complexes. This both greatly expands applications of mass spectrometry and makes the activation and dissociation of complex ions an integral part of large molecule mass spectrometry. A corollary of the much greater number of internal degrees of freedom and high density of states associated with molecular complexity is that internal energies much higher than the dissociation energies for competing fragmentation processes are required for observable fragmentation in time scales sampled by mass spectrometers. This article describes the kinetics of surface-induced dissociation (SID), a particularly efficient activation method for complex ions. Two very important characteristics of SID are very rapid, sub-picosecond activation and precise control of ion internal energy by varying ion collision energy. The nature of the surface plays an important role in SID, determining both efficiency and mechanism of ion activation. Surface composition and morphology strongly influence the relative importance of competing reactions of SID, ion capture (soft-landing), surface reaction and neutralization. The important features of SID and ion soft-landing are described briefly in this review and more fully in the recommended reading list.

  11. 75 FR 42762 - Statement of Organization, Functions, and Delegations of Authority

    Science.gov (United States)

    2010-07-22

    ... Planning, Research and Evaluation, which involved the exercise of this authority prior to the effective... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Statement of... authority pertaining to authorities delegated herein. (d) Effective Date. This delegation is effective on...

  12. How pH Modulates the Reactivity and Selectivity of a Siderophore-Associated Flavin Monooxygenase

    Science.gov (United States)

    2015-01-01

    Flavin-containing monooxygenases (FMOs) catalyze the oxygenation of diverse organic molecules using O2, NADPH, and the flavin adenine dinucleotide (FAD) cofactor. The fungal FMO SidA initiates peptidic siderophore biosynthesis via the highly selective hydroxylation of l-ornithine, while the related amino acid l-lysine is a potent effector of reaction uncoupling to generate H2O2. We hypothesized that protonation states could critically influence both substrate-selective hydroxylation and H2O2 release, and therefore undertook a study of SidA’s pH-dependent reaction kinetics. Consistent with other FMOs that stabilize a C4a-OO(H) intermediate, SidA’s reductive half reaction is pH independent. The rate constant for the formation of the reactive C4a-OO(H) intermediate from reduced SidA and O2 is likewise independent of pH. However, the rate constants for C4a-OO(H) reactions, either to eliminate H2O2 or to hydroxylate l-Orn, were strongly pH-dependent and influenced by the nature of the bound amino acid. Solvent kinetic isotope effects of 6.6 ± 0.3 and 1.9 ± 0.2 were measured for the C4a-OOH/H2O2 conversion in the presence and absence of l-Lys, respectively. A model is proposed in which l-Lys accelerates H2O2 release via an acid–base mechanism and where side-chain position determines whether H2O2 or the hydroxylation product is observed. PMID:24490904

  13. Rumen Degradability and Post-ruminal Digestion of Dry Matter, Nitrogen and Amino Acids of Three Protein Supplements.

    Science.gov (United States)

    Gao, Wei; Chen, Aodong; Zhang, Bowen; Kong, Ping; Liu, Chenli; Zhao, Jie

    2015-04-01

    This study evaluated the in situ ruminal degradability, and subsequent small intestinal digestibility (SID) of dry matter, crude protein (CP), and amino acids (AA) of cottonseed meal (CSM), sunflower seed meal (SFSM) and distillers dried grains with solubles (DDGS) by using the modified three-step in vitro procedure. The ruminal degradability and subsequent SID of AA in rumen-undegradable protein (RUP-AA) varied among three protein supplements. The result show that the effective degradability of DM for SFSM, CSM, and DDGS was 60.8%, 56.4%, and 41.0% and their ruminal fermentable organic matter was 60.0%, 55.9%, and 39.9%, respectively. The ruminal degradable protein (RDP) content in CP for SFSM, CSM, and DDGS was 68.3%, 39.0%, and 32.9%, respectively, at the ruminal solid passage rate of 1.84%/h. The SFSM is a good source of RDP for rumen micro-organisms; however, the SID of RUP of SFSM was lower. The DDGS and CSM are good sources of RUP for lambs to digest in the small intestine to complement ruminal microbial AA of growing lambs. Individual RUP-AA from each protein source was selectively removed by the rumen micro-organisms, especially for Trp, Arg, His, and Lys (p<0.01). The SID of individual RUP-AA was different within specific RUP origin (p<0.01). Limiting amino acid was Leu for RUP of CSM and Lys for both RUP of SFSM and DDGS, respectively. Therefore, different protein supplements with specific limitations should be selected and combined carefully in growing lambs ration to optimize AA balance.

  14. Prophylactic immunoglobulin therapy in secondary immune deficiency

    DEFF Research Database (Denmark)

    Agostini, Carlo; Blau, Igor-Wolfgang; Kimby, Eva

    2016-01-01

    RT in secondary immune deficiencies (SID), and most published guidelines are mere extrapolations from the experience in PID. AREAS COVERED: In this article, four European experts provide their consolidated opinion on open questions surrounding the prophylactic use of IgRT in SID, based on their clinical...

  15. Ecosystem-Based Adaptation to Climate Change in Caribbean Small Island Developing States: Integrating Local and External Knowledge

    Directory of Open Access Journals (Sweden)

    Tiina Kurvits

    2012-08-01

    Full Text Available Caribbean Small Island Developing States (SIDS are vulnerable to climate change impacts including sea level rise, invasive species, ocean acidification, changes in rainfall patterns, increased temperatures, and changing hazard regimes including hurricanes, floods and drought. Given high dependencies in Caribbean SIDS on natural resources for livelihoods, a focus on ecosystems and their interaction with people is essential for climate change adaptation. Increasingly, ecosystem-based adaptation (EbA approaches are being highlighted as an approach to address climate change impacts. Specifically, EbA encourages the use of local and external knowledge about ecosystems to identify climate change adaptation approaches. This paper critically reviews EbA in Caribbean SIDS, focusing on the need to integrate local and external knowledge. An analysis of current EbA in the Caribbean is undertaken alongside a review of methodologies used to integrate local and external expertise for EbA. Finally key gaps, lessons learnt and suggested ways forward for EbA in Caribbean SIDS and potentially further afield are identified.

  16. Overopvarmning og pludselig uventet spaedbørnsdød. Temperaturregulering i relation til maveleje, den mulige patogenese for pludselig spoedbørnsdød

    DEFF Research Database (Denmark)

    Helweg-Larsen, K; Banner, Jytte; Bille, H

    1994-01-01

    The incidence of sudden infant death syndrome (SIDS) in Denmark varied in the period 1982-1991 between 1.5 and 1.9 per 1000 livebirths. In December 1991 recommendations concerning infants' sleeping position were published by The Danish National Board of Health in order to reduce the risk of SIDS....... Babies were recommended to be placed in the supine or side position when sleeping. Parents have followed the guidelines. Most Danish infants are now sleeping on their back or in the side position. Simultaneously, the number of SIDS dropped from about 110 to 40 per year. The incidence decreased to 1.......2 in 1992 and was further reduced in 1993 to 0.6 per 1000 live births. Referring to our knowledge of the infant's temperature regulation we discuss why the prone position is a risk factor for SIDS. The head is the site of up to 85% of heat loss in an infant in bed. Placed in the prone position, the infant...

  17. 77 FR 61761 - Delegation of Authority

    Science.gov (United States)

    2012-10-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Community Living Delegation of... the Administrator, or his or her subordinates, involving the exercise of these authorities prior to the effective date of this delegation. This delegation is effective upon date of signature. Dated...

  18. Dummy (pacifier) use and sudden infant death syndrome: Potential advantages and disadvantages

    NARCIS (Netherlands)

    Horne, R.S.C.; Moon, R.Y; L'Hoir, M.P.; Blair, P.S.

    2014-01-01

    The large decline in deaths due to the sudden infant death syndrome (SIDS) in the last 20 years in many countries is largely due to risk-reduction advice resulting from observational studies that examined the relationship between infant care practices and SIDS. Most of this advice remains largely

  19. Febrile convulsions and sudden infant death syndrome

    DEFF Research Database (Denmark)

    Vestergaard, Mogens; Basso, Olga; Henriksen, Tine Brink

    2002-01-01

    It has been suggested that sudden infant death syndrome (SIDS) and febrile convulsions are related aetiologically. We compared the risk of SIDS in 9877 siblings of children who had had febrile convulsions with that of 20.177 siblings of children who had never had febrile convulsions. We found...

  20. Standardized ileal digestibility of amino acids in eight genotypes of barley fed to growing pigs

    DEFF Research Database (Denmark)

    Spindler, H K; Mosenthin, R; Rosenfelder, Pia

    2016-01-01

    . In conclusion, a comprehensive database on chemical composition and SID of CP and AA in eight current barley genotypes has been made available. However, as present SID values are lower compared to feed tables, adjustments are required to minimize the risk of overestimating the actual protein value of barley...

  1. [Evaluation of the lifetime of nail markings during polio vaccinations in Chad].

    Science.gov (United States)

    Quoc Cuong, Huong; Schlumberger, Martin; Garba Tchang, Salomon; Ould Cheikh, Dah; Savès, Marianne; Mallah, Barah; Demtilo Attilo, Jacques; Ngangro Mosurel, Ndeikoundam; Gamatié, Youssouf

    2010-01-01

    SID (Supplemental Immunization Days) is a special strategy intended to accelerate eradication of poliomyelitis in countries where it is still endemic (India, Afghanistan, and Pakistan in Asia, and Nigeria in Africa). This strategy is also applied in Nigeria's neighbours (Cameroon, Chad, Niger and Benin). Since the poliomyelitis virus was imported from Nigeria in 2001, Chad has reported cases of poliomyelitis every year. After 30 SIDs in Chad and the inaccurate or false attribution of side-effects to polio vaccines, some groups persistently refuse polio vaccination. To ascertain the true coverage of SID, the Ministry of Health and several partners (WHO, UNICEF and Rotary) conduct external coverage evaluations, to identify the under-vaccinated areas where population may be refusing immunization. The nails of the children receiving vaccinations are marked with indelible ink and those markings are the best indicator of the area's actual SID coverage. When coverage investigators arrive and propose vaccination to all children not immunized during SID, mothers who wish to refuse vaccination may claim that the children's markings disappeared after a few days, due to bathing. WHO experts have found that markings applied to their own nails with the WHO-recommended markers persist a few weeks, but others suggested that the markings may disappear much faster among children living in a traditional tropical environment. Until now, the lifetime of these markings has not been tested among children in Africa. To determine the lifetime of the fingernail markings after SID and factors that influence this lifetime in children young than 5 years old in Chad. This prospective cohort study of 200 children (aged 0 to 59 months) took place from March to May 2009 in Milezi, a health zone north of Ndjamena, the capital of Chad, in central Africa. These children received nail markings on their left little finger with an indelible marker pen provided by WHO. The finger was monitored for 35

  2. Challenging Authority During an Emergency-the Effect of a Teaching Intervention.

    Science.gov (United States)

    Friedman, Zeev; Perelman, Vsovolod; McLuckie, Duncan; Andrews, Meghan; Noble, Laura M K; Malavade, Archana; Bould, M Dylan

    2017-08-01

    Previous research has shown that residents were unable to effectively challenge a superior's wrong decision during a crisis situation, a problem that can contribute to preventable mortality. We aimed to assess whether a teaching intervention enabled residents to effectively challenge clearly wrong clinical decisions made by their staff. Following ethics board approval, second year residents were randomized to a teaching intervention targeting cognitive skills needed to challenge a superior's decision, or a control group receiving general crisis management instruction. Two weeks later, subjects participated in a simulated crisis that presented them with opportunities to challenge clearly wrong decisions in a can't-intubate-can't-ventilate scenario. It was only disclosed that the staff was a confederate during the debriefing. Performances were video recorded and assessed by two raters blinded to group allocation using the modified Advocacy-Inquiry Score. Fifty residents completed the study. The interrater reliability of the modified Advocacy-Inquiry Scores (intraclass correlation coefficient = 0.87) was excellent. The median (interquartile range) best modified Advocacy-Inquiry Score was significantly better in the intervention group 5.0 (4.50-5.62 [4-6]) than in the control group 3.5 (3.0-4.75 [3-6]) (p authority during a life-threatening crisis situation. This educational gap can have significant implications for patients' safety.

  3. Authoring Tools

    Science.gov (United States)

    Treviranus, Jutta

    Authoring tools that are accessible and that enable authors to produce accessible Web content play a critical role in web accessibility. Widespread use of authoring tools that comply to the W3C Authoring Tool Accessibility Guidelines (ATAG) would ensure that even authors who are neither knowledgeable about nor particularly motivated to produce accessible content do so by default. The principles and techniques of ATAG are discussed. Some examples of accessible authoring tools are described including authoring tool content management components such as TinyMCE. Considerations for creating an accessible collaborative environment are also covered. As part of providing accessible content, the debate between system-based personal optimization and one universally accessible site configuration is presented. The issues and potential solutions to address the accessibility crisis presented by the advent of rich internet applications are outlined. This challenge must be met to ensure that a large segment of the population is able to participate in the move toward the web as a two-way communication mechanism.

  4. Becoming Co-Authors: Toward Sharing Authority in Religious Education

    Science.gov (United States)

    Kim, Hyun-Sook

    2009-01-01

    This article offers an alternative model, the model of shared authority, to the traditional, authoritarian model for authority and obedience for Religious Education. This model moves away from the authoritarian model of a teacher as the authority and the students as obedient listeners in the direction of a shared authority model in which teachers…

  5. Management of the Regulatory Authority Information

    International Nuclear Information System (INIS)

    Suman, H.

    2003-01-01

    Safe Management of the Regulatory Authority Information is one of the essential elements to ensure the effectiveness of the regulatory program as a whole. This paper briefly describes the information management basis in RNRO, which is in charge of the regulatory authority tasks in Syria. SINA-2, a computational tool prepared in RNRO for managing the information related to the inventory of radiation sources and users, is also introduced

  6. 7 CFR 8.5 - Revocation of present authorizations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Revocation of present authorizations. 8.5 Section 8.5 Agriculture Office of the Secretary of Agriculture 4-H CLUB NAME AND EMBLEM § 8.5 Revocation of present authorizations. Effective September 16, 1985, authorization permits for the use of the 4-H Club Name and Emblem...

  7. Development and Validation of an Agency for Healthcare Research and Quality Indicator for Mortality After Congenital Heart Surgery Harmonized With Risk Adjustment for Congenital Heart Surgery (RACHS-1) Methodology.

    Science.gov (United States)

    Jenkins, Kathy J; Koch Kupiec, Jennifer; Owens, Pamela L; Romano, Patrick S; Geppert, Jeffrey J; Gauvreau, Kimberlee

    2016-05-20

    The National Quality Forum previously approved a quality indicator for mortality after congenital heart surgery developed by the Agency for Healthcare Research and Quality (AHRQ). Several parameters of the validated Risk Adjustment for Congenital Heart Surgery (RACHS-1) method were included, but others differed. As part of the National Quality Forum endorsement maintenance process, developers were asked to harmonize the 2 methodologies. Parameters that were identical between the 2 methods were retained. AHRQ's Healthcare Cost and Utilization Project State Inpatient Databases (SID) 2008 were used to select optimal parameters where differences existed, with a goal to maximize model performance and face validity. Inclusion criteria were not changed and included all discharges for patients model includes procedure risk group, age (0-28 days, 29-90 days, 91-364 days, 1-17 years), low birth weight (500-2499 g), other congenital anomalies (Clinical Classifications Software 217, except for 758.xx), multiple procedures, and transfer-in status. Among 17 945 eligible cases in the SID 2008, the c statistic for model performance was 0.82. In the SID 2013 validation data set, the c statistic was 0.82. Risk-adjusted mortality rates by center ranged from 0.9% to 4.1% (5th-95th percentile). Congenital heart surgery programs can now obtain national benchmarking reports by applying AHRQ Quality Indicator software to hospital administrative data, based on the harmonized RACHS-1 method, with high discrimination and face validity. © 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  8. Isotope dilution analysis for urinary fentanyl and its main metabolite, norfentanyl, in patients by isotopic fractionation using capillary gas chromatography

    Energy Technology Data Exchange (ETDEWEB)

    Sera, Shoji; Goromaru, Tsuyoshi [Fukuyama Univ., Hiroshima (Japan). Faculty of Pharmacy and Pharmaceutical Sciences; Sameshima, Teruko; Kawasaki, Koichi; Oda, Toshiyuki

    1998-07-01

    Isotope dilution analysis was applied to determine urinary excretion of fentanyl (FT) and its main metabolite, norfentanyl (Nor-FT), by isotopic fractionation using a capillary gas chromatograph equipped with a surface ionization detector (SID). Urinary FT was determined quantitatively in the range of 0.4-40 ng/ml using deuterium labeled FT (FT-{sup 2}H{sub 19}), as an internal standard. We also performed isotope dilution analysis of Nor-FT in urine. N-Alkylation was necessary to sensitively detect Nor-FT with SID. Methyl derivative was selected from 3 kinds of N-alkyl derivatives to increase sensitivity and peak resolution, and to prevent interference with urinary compound. Nor-FT concentration was quantitatively determined in the range of 10-400 ng/ml using deuterium labeled Nor-FT (Nor-FT-{sup 2}H{sub 10}). No endogenous compounds or concomitant drugs interfered with the detection of FT and Nor-FT in the urine of patients. The present method will be useful for pharmacokinetic studies and the evaluation of drug interactions in FT metabolism. (author)

  9. Isotope dilution analysis for urinary fentanyl and its main metabolite, norfentanyl, in patients by isotopic fractionation using capillary gas chromatography

    International Nuclear Information System (INIS)

    Sera, Shoji; Goromaru, Tsuyoshi; Sameshima, Teruko; Kawasaki, Koichi; Oda, Toshiyuki

    1998-01-01

    Isotope dilution analysis was applied to determine urinary excretion of fentanyl (FT) and its main metabolite, norfentanyl (Nor-FT), by isotopic fractionation using a capillary gas chromatograph equipped with a surface ionization detector (SID). Urinary FT was determined quantitatively in the range of 0.4-40 ng/ml using deuterium labeled FT (FT- 2 H 19 ), as an internal standard. We also performed isotope dilution analysis of Nor-FT in urine. N-Alkylation was necessary to sensitively detect Nor-FT with SID. Methyl derivative was selected from 3 kinds of N-alkyl derivatives to increase sensitivity and peak resolution, and to prevent interference with urinary compound. Nor-FT concentration was quantitatively determined in the range of 10-400 ng/ml using deuterium labeled Nor-FT (Nor-FT- 2 H 10 ). No endogenous compounds or concomitant drugs interfered with the detection of FT and Nor-FT in the urine of patients. The present method will be useful for pharmacokinetic studies and the evaluation of drug interactions in FT metabolism. (author)

  10. Standardized ileal digestibility of amino acids in eight genotypes of soft winter wheat fed to growing pigs

    DEFF Research Database (Denmark)

    Rosenfelder, P; Mosenthin, R; Spindler, H K

    2015-01-01

    such as fiber fractions are not suitable due to low variation among the 8 genotypes. The present study provides a comprehensive database on nutritional composition and SID of CP and AA of 8 wheat genotypes grown under identical conditions. Because the SID values in these genotypes are lower when compared...

  11. Birth Cohort Differences in Sexual Identity Development Milestones among HIV-Negative Gay and Bisexual Men in the United States.

    Science.gov (United States)

    Grov, Christian; Rendina, H Jonathon; Parsons, Jeffrey T

    2017-10-12

    The coming-out process for gay and bisexual men (GBM) involves crossing sexual identity development (SID) milestones: (1) self-awareness of sexual attraction to the same sex, (2) self-acceptance of an identity as gay or bisexual, (3) disclosure of this sexual identity to others, and (4) having sex with someone of the same sex. We examined trends in SID milestones by birth cohort in a 2015 U.S. national sample of GBM (n = 1,023). Birth cohort was independent of when men first felt sexually attracted to someone of the same sex (median age 11 to 12). However, with the exception of age of first same-sex attraction, older cohorts tended to pass other milestones at later ages than younger cohorts. Latent class analysis (LCA) of SID milestone patterns identified three subgroups. The majority (84%) began sexual identity development with same-sex attraction around the onset of puberty (i.e., around age 10) and progressed to self-identification, same-sex sexual activity, and coming out-in that order. The other two classes felt same-sex attraction during teen years (ages 12.5 to 18.0) but achieved the remaining SID milestones later in life. For 13% of men, this was during early adulthood; for 3% of men, this was in middle adulthood. Findings highlight the need to monitor ongoing generational differences in passing SID milestones.

  12. Evaluation methods used on health information systems (HISs) in Iran and the effects of HISs on Iranian healthcare: a systematic review.

    Science.gov (United States)

    Ahmadian, Leila; Nejad, Simin Salehi; Khajouei, Reza

    2015-06-01

    The most important goal of a health information system (HIS) is improvement of quality, effectiveness and efficiency of health services. To achieve this goal, health care systems should be evaluated continuously. The aim of this paper was to study the impacts of HISs in Iran and the methods used for their evaluation. We systematically searched all English and Persian papers evaluating health information systems in Iran that were indexed in SID, Magiran, Iran medex, PubMed and Embase databases until June 2013. A data collection form was designed to extract required data such as types of systems evaluated, evaluation methods and tools. In this study, 53 out of 1103 retrieved articles were selected as relevant and reviewed by the authors. This study indicated that 28 studies used questionnaires to evaluate the system and in 27 studies the study instruments were distributed within a research population. In 26 papers the researchers collected the information by means of interviews, observations, heuristic evaluation and the review of documents and records. The main effects of the evaluated systems in health care settings were improving quality of services, reducing time, increasing accessibility to information, reducing costs and decreasing medical errors. Evaluation of health information systems is central to their development and enhancement, and to understanding their effect on health and health services. Despite numerous evaluation methods available, the reviewed studies used a limited number of methods to evaluate HIS. Additionally, the studies mainly discussed the positive effects of HIS on health care services. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  13. Distributed modeling for road authorities

    NARCIS (Netherlands)

    Luiten, G.T.; Bõhms, H.M.; Nederveen, S. van; Bektas, E.

    2013-01-01

    A great challenge for road authorities is to improve the effectiveness and efficiency of their core processes by improving data exchange and sharing using new technologies such as building information modeling (BIM). BIM has already been successfully implemented in other sectors, such as

  14. Protective factors for adolescent violence against authority.

    Science.gov (United States)

    Ibabe, Izaskun; Jaureguizar, Joana; Bentler, Peter M

    2013-01-01

    Both the family and school environments influence adolescents' violence, but there is little research focusing simultaneously on the two contexts. This study analyzed the role of positive family and classroom environments as protective factors for adolescents' violence against authority (parent abuse and teacher abuse) and the relations between antisocial behavior and child-to-parent violence or student-to-teacher violence. The sample comprised 687 Spanish students aged 12-16 years, who responded to the Family Environment Scale (FES) and the Classroom Environment Scale (CES). Structural Equation Modeling was used to test our model of violent behavior towards authority based on Catalano and Hawkins' Social Developmental Model (1996). Perceived family cohesion and organization showed an inverse association with parent abuse, suggesting that a positive family environment was a protective factor for the development of violence against parents. Family and classroom environments had direct effects on adolescents' violence against authority, and antisocial behavior showed a mediating effect in this relationship. The model accounted for 81% of the variance in violence against authority. As family environment was a better predictor of violence against authority than school environment, intervention efforts to reduce rates of adolescent violence should focus on helping parents to increase family cohesion and to manage conflictive relationships with their children.

  15. Organizing Books and Authors by Multilayer SOM.

    Science.gov (United States)

    Zhang, Haijun; Chow, Tommy W S; Wu, Q M Jonathan

    2016-12-01

    This paper introduces a new framework for the organization of electronic books (e-books) and their corresponding authors using a multilayer self-organizing map (MLSOM). An author is modeled by a rich tree-structured representation, and an MLSOM-based system is used as an efficient solution to the organizational problem of structured data. The tree-structured representation formulates author features in a hierarchy of author biography, books, pages, and paragraphs. To efficiently tackle the tree-structured representation, we used an MLSOM algorithm that serves as a clustering technique to handle e-books and their corresponding authors. A book and author recommender system is then implemented using the proposed framework. The effectiveness of our approach was examined in a large-scale data set containing 3868 authors along with the 10500 e-books that they wrote. We also provided visualization results of MLSOM for revealing the relevance patterns hidden from presented author clusters. The experimental results corroborate that the proposed method outperforms other content-based models (e.g., rate adapting poisson, latent Dirichlet allocation, probabilistic latent semantic indexing, and so on) and offers a promising solution to book recommendation, author recommendation, and visualization.

  16. Rumen Degradability and Post-ruminal Digestion of Dry Matter, Nitrogen and Amino Acids of Three Protein Supplements

    Directory of Open Access Journals (Sweden)

    Wei Gao

    2015-04-01

    Full Text Available This study evaluated the in situ ruminal degradability, and subsequent small intestinal digestibility (SID of dry matter, crude protein (CP, and amino acids (AA of cottonseed meal (CSM, sunflower seed meal (SFSM and distillers dried grains with solubles (DDGS by using the modified three-step in vitro procedure. The ruminal degradability and subsequent SID of AA in rumen-undegradable protein (RUP-AA varied among three protein supplements. The result show that the effective degradability of DM for SFSM, CSM, and DDGS was 60.8%, 56.4%, and 41.0% and their ruminal fermentable organic matter was 60.0%, 55.9%, and 39.9%, respectively. The ruminal degradable protein (RDP content in CP for SFSM, CSM, and DDGS was 68.3%, 39.0%, and 32.9%, respectively, at the ruminal solid passage rate of 1.84%/h. The SFSM is a good source of RDP for rumen micro-organisms; however, the SID of RUP of SFSM was lower. The DDGS and CSM are good sources of RUP for lambs to digest in the small intestine to complement ruminal microbial AA of growing lambs. Individual RUP-AA from each protein source was selectively removed by the rumen micro-organisms, especially for Trp, Arg, His, and Lys (p<0.01. The SID of individual RUP-AA was different within specific RUP origin (p<0.01. Limiting amino acid was Leu for RUP of CSM and Lys for both RUP of SFSM and DDGS, respectively. Therefore, different protein supplements with specific limitations should be selected and combined carefully in growing lambs ration to optimize AA balance.

  17. The Social Context of Emotion: Effects of Ethnicity and Authority/Peer Status on the Emotional Reports of African American College Students.

    Science.gov (United States)

    Vrana, Scott R.; Rollock, David

    1996-01-01

    Examines the emotional impact of inter- and intraethnic interactions with peers and authority figures among black undergraduates (n=66). Subjects reported more negative emotions in hypothetical interactions with whites and intensification of both positive and negative affect in interactions with authority figures. Range of reported effect was more…

  18. 75 FR 6399 - Statement of Organization, Functions and Delegation of Authority

    Science.gov (United States)

    2010-02-09

    ... DUCS Case Managers which, in effect, involved the exercise of these authorities prior to the effective... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Statement of... the January 12, 2010 earthquake in Haiti. (c) Effective Date This delegation of authority is effective...

  19. Design Management, Learning and Innovation: Results from a Portuguese Online Questionnaire

    Science.gov (United States)

    Monteiro Barata, José M.

    2013-01-01

    This paper is an output of a Portuguese public research project: "DeSid"--"design as a company's strategic resource: a study of the impacts of design" (FCT). The "DeSid" research project was created with the main purpose to make a diagnosis of the use of design inside the Portuguese manufacturing industry. This paper…

  20. Outpatient management of steroid-induced hyperglycaemia and steroid-induced diabetes in people with lymphoproliferative disorders treated with intermittent high dose steroids

    Directory of Open Access Journals (Sweden)

    Jennifer Vidler

    2017-09-01

    Eighty-three people were diagnosed with a lymphoproliferative disorder, of whom 6 had known Type 2 diabetes. Fifty-three people without known diabetes were screened by HbA1c and random venous plasma glucose. All patients (n = 34 subsequently prescribed HDS checked capillary blood glucose (CBG pre-breakfast and pre-evening meal. Treatment algorithms used initiation and/or dose titration of gliclazide or human NPH insulin, aiming for pre-meal CBG 5–11 mmol/l. Type 2 diabetes was identified in 4/53 people screened (7.5%. Of 34 people treated with HDS, 17 (44% developed SIH/SID. All 7 people with Type 2 diabetes developed SIH and 3 required insulin. Of 27 people without known diabetes, 8 (30% developed SID and 1 required insulin. Pre-treatment HbA1c was higher in people who developed SID compared to those that did not (p = 0.002. This is the first report of a SID/SIH detection and treatment protocol for use in people with lymphoproliferative disorders receiving intermittent HDS, demonstrating its feasibility and safety.

  1. Renewable Energy Development in Small Island Developing States of the Pacific

    Directory of Open Access Journals (Sweden)

    Matthew Dornan

    2015-07-01

    Full Text Available Small Island Developing States (SIDS of the Pacific over the last decade have established some of the most ambitious renewable energy targets in the world. The promotion of renewable energy has been motivated by a desire to lessen dependence on fossil fuels, given the adverse economic impacts of high oil prices on these countries. Efforts to attract development assistance and to strengthen the position of Pacific SIDS in climate change negotiations have likely also played a role. This paper explores the development of renewable energy resources in the Pacific through a public policy lens. The ambitious renewable energy targets established by Pacific SIDS are argued to be appropriate in some cases, but in other cases are criticised on economic grounds. A potential trade-off is identified between the risk mitigation benefits and poverty alleviation benefits of different renewable technology investments, with questions raised about whether support for the former rather than the latter by development partners is appropriate. A number of institutional and financial challenges to the development of renewable energy resources in Pacific SIDS are also discussed.

  2. Enhancing Author Information for CERN Document Server: Creating an Author Collection and Using Author Disambiguation Methods

    CERN Document Server

    AUTHOR|(CDS)2096274; Witowski, Sebastian

    Authors are a substantial part of queries in digital libraries, where the results are reflecting the service quality and success. Ambiguous author names can confuse users and cause an inaccurate relation between authorships and individual researchers. Providing a set of disambiguated authors is challenging and related to data integration, since this is done in several ways and by different systems, both manually and automatically. Many disambiguation algorithms have been proposed in the literature, where the most solutions are solving the ambiguities by applying machine learning techniques. However, such problems cannot be solved with an accuracy of 100%. Our contributions to the CERN Document Server presented in this work consists of two parts: first, we create and deploy an author knowledge data base (collection) and second, we link authors of bibliographic records back to their authority records. For the latter, we use a library providing machine learning tools for clustering (where we use trained data fro...

  3. Teaching the Teacher: Tutoring SimStudent Leads to More Effective Cognitive Tutor Authoring

    Science.gov (United States)

    Matsuda, Noboru; Cohen, William W.; Koedinger, Kenneth R.

    2015-01-01

    SimStudent is a machine-learning agent initially developed to help novice authors to create cognitive tutors without heavy programming. Integrated into an existing suite of software tools called Cognitive Tutor Authoring Tools (CTAT), SimStudent helps authors to create an expert model for a cognitive tutor by tutoring SimStudent on how to solve…

  4. El sistema de innovación design_driven como modelo estratégico y la propuesta de política nacional de diseño para Chile 2007

    Directory of Open Access Journals (Sweden)

    Katherine Mollenhauer

    2016-08-01

    Full Text Available Durante el primer semestre de 2007 la autora en su calidad de Coordinadora Ejecutiva de la Comisión participó en la creación de una Propuesta de Política Nacional de Diseño para Chile. La propuesta fue presentada al Ministro de Economía de la época Sr. Alejandro Ferreiro, el 27 de julio del mismo año, en el evento MIPYME DISEÑA bajo el lema “Innovar, Crecer, Competir”. Esta propuesta de política pública se articuló teniendo como base conceptual y metodológica el Sistema de Innovación Design_driven (SID_d, modelo estratégico e instrumental que permite mapear y articular los habilitantes de una política de Innovación Design_driven. El SID_d está constituido por los actores, las actuaciones, los proyectos, la dimensión espacio-temporal, el modelamiento de procesos de Innovación Design_driven genera un sistema clasificatorio que permite caracterizar –al menos– tres tipologías: 1 SID_d nivel avanzado, 2 SID_d nivel intermedio y 3 SID_d nivel emergente. Por otra parte, este modelo como instrumento estratégico permite visualizar un modelo ideal para países en vías de desarrollo y es útil como referente para la propuesta de estrategias que fortalezcan el desarrollo, proyección y consolidación del Diseño en SID_d del tipo emergente. Este modelo fue desarrollado por la autora como resultado de su trabajo de tesis doctoral entre los años 2004 y 2006 y considera los resultados de la investigación realizada sobre cuatro casos europeos, España, Portugal, Italia y Finlandia, en los cuales el Diseño es parte del Sistema Nacional de Innovación. Este artículo explica la configuración del Sistema de Innovación Design_Driven (SID_d como modelo estratégico base para el desarrollo del Diseño en países emergentes y revisa los principales componentes de la citada propuesta de Política Nacional de Diseño.

  5. 76 FR 9353 - Statement of Delegation of Authority

    Science.gov (United States)

    2011-02-17

    ... involved the exercise of these authorities prior to the effective date of this delegation. This delegation... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Statement of Delegation of Authority Notice is hereby given that I have delegated to the Administrator, Health Resources...

  6. Salicylic acid prevents Trichoderma harzianum from entering the vascular system of roots.

    Science.gov (United States)

    Alonso-Ramírez, Ana; Poveda, Jorge; Martín, Ignacio; Hermosa, Rosa; Monte, Enrique; Nicolás, Carlos

    2014-10-01

    Trichoderma is a soil-borne fungal genus that includes species with a significant impact on agriculture and industrial processes. Some Trichoderma strains exert beneficial effects in plants through root colonization, although little is known about how this interaction takes place. To better understand this process, the root colonization of wild-type Arabidopsis and the salicylic acid (SA)-impaired mutant sid2 by a green fluorescent protein (GFP)-marked Trichoderma harzianum strain was followed under confocal microscopy. Trichoderma harzianum GFP22 was able to penetrate the vascular tissue of the sid2 mutant because of the absence of callose deposition in the cell wall of root cells. In addition, a higher colonization of sid2 roots by GFP22 compared with that in Arabidopsis wild-type roots was detected by real-time polymerase chain reaction. These results, together with differences in the expression levels of plant defence genes in the roots of both interactions, support a key role for SA in Trichoderma early root colonization stages. We observed that, without the support of SA, plants were unable to prevent the arrival of the fungus in the vascular system and its spread into aerial parts, leading to later collapse. © 2014 BSPP AND JOHN WILEY & SONS LTD.

  7. Terbinafine hydrochloride treatment of Microsporum canis experimentally-induced ringworm in cats.

    Science.gov (United States)

    Kotnik, T; Kozuh Erzen, N; Kuzner, J; Drobnic-Kosorok, M

    2001-11-08

    Cats represent the most important source of Microsporum canis infection to people. Terbinafine hydrochloride is commonly used in the treatment of microsporosis. Its fungicidal action permits short period of treatment. It was our objective to evaluate the effectiveness of this drug in treatment of microsporosis in cats. We treated nine experimentally M. canis infected cats with terbinafine at a dose of 10-20mg/kg SID (low-dose group, LDG), nine cats with 30-40mg/kg SID (high-dose group, HDG), and nine cats were left untreated (control group, CG). The drug's levels in cats' plasma and hair were measured by a reversed-phase high performance liquid chromatographic method (RP-HPLC) and the cats' cure was followed by Wood's lamp illumination, microscopic exam and fungal culture. We showed no difference between the clinical course in CG and LDG, but HDG were significantly differentiated from both other groups. Terbinafine levels in plasma at 120 days of treatment were not statistically different among LDG (4.13 microg/l) and HDG (5.48 microg/l), but levels in hair of LDG (1.24 microg/l) and HDG (3.62 microg/l) were significantly different. Terbinafine can be used for the treatment of microsporosis in cats in the dose of 30-40mg/kg SID.

  8. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 20

    International Nuclear Information System (INIS)

    1989-03-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness

  9. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 24

    International Nuclear Information System (INIS)

    1993-01-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness

  10. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 20

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1989-03-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness.

  11. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 25

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-01-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness.

  12. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 19

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-01-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness.

  13. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 18

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1986-12-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness.

  14. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 19

    International Nuclear Information System (INIS)

    1988-01-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness

  15. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 25

    International Nuclear Information System (INIS)

    1994-01-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness

  16. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 18

    International Nuclear Information System (INIS)

    1986-12-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness

  17. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 21

    International Nuclear Information System (INIS)

    1990-02-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness

  18. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 23

    International Nuclear Information System (INIS)

    1992-01-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness

  19. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 22

    International Nuclear Information System (INIS)

    1991-01-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness

  20. National competent authorities responsible for approvals and authorizations in respect of the transport of radioactive material. List no. 23

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-01-01

    Any national or international authority designated or otherwise recognised as such for any purpose in connection with the transport Regulations is known as a competent authority. In the Member States such a body has the responsibility for establishing national legislation to bring the Agency's transport Regulations into effect and for assuring compliance with its requirements. Depending on the national regulatory or institutional framework the functions of the competent authority may be assigned to one or more bodies. To assist Member States in implementing the transport Regulations and carrying out responsibility for compliance assurance, the IAEA continues to maintain this updated list of designated national competent authorities. Member States are annually requested to verify the list for correctness and completeness.