COMPARISON OF POSTOP SIA IN MSICS WITH STRAIGHT INCISION VERSUS FROWN INCISION

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Shayana Bhumbla

2017-05-01

Full Text Available BACKGROUND Surgically-Induced Astigmatism (SIA is one of the commonest causes of poor postoperative vision even after uneventful cataract surgery. Recent advances have led to a newer concept of “refractive cataract surgery.” The aim of the study is to study the comparison of postop SIA in Manual Small Incision Cataract Surgery (MSICS with straight versus frown incision. MATERIALS AND METHODS 50 patients of cataract were divided into 2 groups (25 each - group A underwent MSICS with 6 mm straight incision, group B underwent MSICS with 6 mm frown incision. BCVA, keratometry readings were recorded with auto kerato-refractometer preop, at 1 week, 1 month, 3 months and SIA was calculated with SIA calculator version 2.1, a free software program. RESULTS Mean SIA in group A and B were - 1.14D versus 0.92D at 1 week; 1.26D versus 0.97D at 1 month; 1.29D versus 0.95D at 3 months. The difference was statistically significant at each follow up visit (p<0.05. CONCLUSION Frown incision gives lesser SIA than straight incision in MSICS.

Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes.

Science.gov (United States)

Harduin-Lepers, Anne; Petit, Daniel; Mollicone, Rosella; Delannoy, Philippe; Petit, Jean-Michel; Oriol, Rafael

2008-09-23

The animal sialyltransferases, which catalyze the transfer of sialic acid to the glycan moiety of glycoconjugates, are subdivided into four families: ST3Gal, ST6Gal, ST6GalNAc and ST8Sia, based on acceptor sugar specificity and glycosidic linkage formed. Despite low overall sequence identity between each sialyltransferase family, all sialyltransferases share four conserved peptide motifs (L, S, III and VS) that serve as hallmarks for the identification of the sialyltransferases. Currently, twenty subfamilies have been described in mammals and birds. Examples of the four sialyltransferase families have also been found in invertebrates. Focusing on the ST8Sia family, we investigated the origin of the three groups of alpha2,8-sialyltransferases demonstrated in vertebrates to carry out poly-, oligo- and mono-alpha2,8-sialylation. We identified in the genome of invertebrate deuterostomes, orthologs to the common ancestor for each of the three vertebrate ST8Sia groups and a set of novel genes named ST8Sia EX, not found in vertebrates. All these ST8Sia sequences share a new conserved family-motif, named "C-term" that is involved in protein folding, via an intramolecular disulfide bridge. Interestingly, sequences from Branchiostoma floridae orthologous to the common ancestor of polysialyltransferases possess a polysialyltransferase domain (PSTD) and those orthologous to the common ancestor of oligosialyltransferases possess a new ST8Sia III-specific motif similar to the PSTD. In osteichthyans, we have identified two new subfamilies. In addition, we describe the expression profile of ST8Sia genes in Danio rerio. Polysialylation appeared early in the deuterostome lineage. The recent release of several deuterostome genome databases and paralogons combined with synteny analysis allowed us to obtain insight into events at the gene level that led to the diversification of the ST8Sia genes, with their corresponding enzymatic activities, in both invertebrates and vertebrates. The

Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia gene family: Tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes

Directory of Open Access Journals (Sweden)

Petit Jean-Michel

2008-09-01

Full Text Available Abstract Background The animal sialyltransferases, which catalyze the transfer of sialic acid to the glycan moiety of glycoconjugates, are subdivided into four families: ST3Gal, ST6Gal, ST6GalNAc and ST8Sia, based on acceptor sugar specificity and glycosidic linkage formed. Despite low overall sequence identity between each sialyltransferase family, all sialyltransferases share four conserved peptide motifs (L, S, III and VS that serve as hallmarks for the identification of the sialyltransferases. Currently, twenty subfamilies have been described in mammals and birds. Examples of the four sialyltransferase families have also been found in invertebrates. Focusing on the ST8Sia family, we investigated the origin of the three groups of α2,8-sialyltransferases demonstrated in vertebrates to carry out poly-, oligo- and mono-α2,8-sialylation. Results We identified in the genome of invertebrate deuterostomes, orthologs to the common ancestor for each of the three vertebrate ST8Sia groups and a set of novel genes named ST8Sia EX, not found in vertebrates. All these ST8Sia sequences share a new conserved family-motif, named "C-term" that is involved in protein folding, via an intramolecular disulfide bridge. Interestingly, sequences from Branchiostoma floridae orthologous to the common ancestor of polysialyltransferases possess a polysialyltransferase domain (PSTD and those orthologous to the common ancestor of oligosialyltransferases possess a new ST8Sia III-specific motif similar to the PSTD. In osteichthyans, we have identified two new subfamilies. In addition, we describe the expression profile of ST8Sia genes in Danio rerio. Conclusion Polysialylation appeared early in the deuterostome lineage. The recent release of several deuterostome genome databases and paralogons combined with synteny analysis allowed us to obtain insight into events at the gene level that led to the diversification of the ST8Sia genes, with their corresponding enzymatic

Mārketinga komunikācijas SIA „Amserv Motors”.

OpenAIRE

Iļjenko, Santa

2013-01-01

Maģistra darba nosaukums ir „Mārketinga komunikācijas SIA „Amserv Motors””. Autore mārketinga komunikācijas pēta uzņēmumā SIA „Amserv Motors”, kas ir Toyota un Lexus oficiālais dīleris Latvijā. Maģistra darba mērķis ir izpētīt SIA „Amserv Motors” mārketinga komunikācijas, izvērtējot to priekšrocības un trūkumus, lai sniegtu priekšlikumus to pilnveidošanas iespējām. Darba pirmajā nodaļā raksturoti mārketinga komunikāciju veidi, to galvenās priekšrocības un trūkumi. Otrajā nodaļā autore a...

Assessing the performance of SIA in the EIA context: A case study of South Africa

International Nuclear Information System (INIS)

Pisani, Jacobus A. du; Sandham, Luke A.

2006-01-01

This article, a theoretical perspective based on a literature study, is a critical evaluation of SIA as part of the EIA process in South Africa against the background of international guidelines and best practices. It includes sections on the historical background of the development of SIA in South Africa, the legal status and requirements of SIA in the country, and a critical evaluation of SIA regulation in South Africa. The conclusion reached in the article is that the persistent problems of SIA practice, experienced in other parts of the world, are also evident in South Africa. Apart from institutional, financial and professional constraints, there are also serious problems associated with approach and methods. This conclusion confirms the findings of empirical studies that SIA in South Africa is neglected, that the practice of SIA in South Africa is not yet on a sound footing, and that it does not receive the professional attention it deserves in a country beset by enormous social challenges. To conclude the article recommendations are made to improve the level of SIA practice in South Africa, and the possible significance of this national case study for international practice is indicated

Social anxiety in the general population: introducing abbreviated versions of SIAS and SPS.

Science.gov (United States)

Kupper, Nina; Denollet, Johan

2012-01-01

Social anxiety is characterized by the experience of stress, discomfort and fear in social situations, and is associated with substantial personal and societal burden. Two questionnaires exist that assess the aspects of social anxiety, i.e. social interaction anxiety (SIAS) and social phobia (SPS). There is no agreement in literature on the dimensionality of social anxiety. Further, the length of a questionnaire may negatively affect response rates and participation at follow-up occasions. To explore the structure of social anxiety in the general population, and to examine psychosocial and sociodemographic correlates. Our second aim was to construct abbreviated versions of SIAS and SPS that can be easily used and with minimal burden. A total of 1598 adults from the general Dutch population completed a survey asking information on social anxiety, mood and demographics. Exploratory and confirmatory factor analyses as well as reliability analysis with item-total statistics were performed. Confirmatory factor analysis revealed a 3-factor structure for social phobia, and a 2-factor structure for the SIAS, with the second factor containing both reversely scored items. The abbreviated versions of SPS (11 items) and SIAS (10 items) show excellent discriminant and construct validity (Cronbach's α=.90 and .92), while specificity analysis showed that gender, marital status and educational level (SIAS(10): pSIAS, reducing the questionnaire burden for participants in epidemiological and biobehavioral research. Copyright © 2011 Elsevier B.V. All rights reserved.

GeAs and SiAs monolayers: Novel 2D semiconductors with suitable band structures

Science.gov (United States)

Zhou, Liqin; Guo, Yu; Zhao, Jijun

2018-01-01

Two dimensional (2D) materials provide a versatile platform for nanoelectronics, optoelectronics and clean energy conversion. Based on first-principles calculations, we propose a novel kind of 2D materials - GeAs and SiAs monolayers and investigate their atomic structure, thermodynamic stability, and electronic properties. The calculations show that monolayer GeAs and SiAs sheets are energetically and dynamically stable. Their small interlayer cohesion energies (0.191 eV/atom for GeAs and 0.178 eV/atom for SiAs) suggest easy exfoliation from the bulk solids that exist in nature. As 2D semiconductors, GeAs and SiAs monolayers possess band gap of 2.06 eV and 2.50 eV from HSE06 calculations, respectively, while their band gap can be further engineered by the number of layers. The relatively small and anisotropic carrier effective masses imply fast electric transport in these 2D semiconductors. In particular, monolayer SiAs is a direct gap semiconductor and a potential photocatalyst for water splitting. These theoretical results shine light on utilization of monolayer or few-layer GeAs and SiAs materials for the next-generation 2D electronics and optoelectronics with high performance and satisfactory stability.

Clinical validation of a non-heteronormative version of the Social Interaction Anxiety Scale (SIAS).

Science.gov (United States)

Lindner, Philip; Martell, Christopher; Bergström, Jan; Andersson, Gerhard; Carlbring, Per

2013-12-19

Despite welcomed changes in societal attitudes and practices towards sexual minorities, instances of heteronormativity can still be found within healthcare and research. The Social Interaction Anxiety Scale (SIAS) is a valid and reliable self-rating scale of social anxiety, which includes one item (number 14) with an explicit heteronormative assumption about the respondent's sexual orientation. This heteronormative phrasing may confuse, insult or alienate sexual minority respondents. A clinically validated version of the SIAS featuring a non-heteronormative phrasing of item 14 is thus needed. 129 participants with diagnosed social anxiety disorder, enrolled in an Internet-based intervention trial, were randomly assigned to responding to the SIAS featuring either the original or a novel non-heteronormative phrasing of item 14, and then answered the other item version. Within-subject, correlation between item versions was calculated and the two scores were statistically compared. The two items' correlations with the other SIAS items and other psychiatric rating scales were also statistically compared. Item versions were highly correlated and scores did not differ statistically. The two items' correlations with other measures did not differ statistically either. The SIAS can be revised with a non-heteronormative formulation of item 14 with psychometric equivalence on item and scale level. Implications for other psychiatric instruments with heteronormative phrasings are discussed.

St8sia2 deficiency plus juvenile cannabis exposure in mice synergistically affect higher cognition in adulthood.

Science.gov (United States)

Tantra, Martesa; Kröcher, Tim; Papiol, Sergi; Winkler, Daniela; Röckle, Iris; Jatho, Jasmin; Burkhardt, Hannelore; Ronnenberg, Anja; Gerardy-Schahn, Rita; Ehrenreich, Hannelore; Hildebrandt, Herbert

2014-12-15

The neural cell adhesion molecule (NCAM) and its functionally linked polysialyltransferases, ST8SIA2 and ST8SIA4, are crucial for synaptic plasticity. Variations in encoding genes have been associated with mental illness. Since cannabinoids can alter NCAM polysialylation, we hypothesized that delta-9-tetrahydrocannabinol (Δ9-THC) might act as environmental 'second hit' regarding cognition of St8sia2(-/-) mice. These mice show per se minor behavioral abnormalities, consisting of reduced anxiety and mild cognitive deficits. Chronic Δ9-THC treatment of juvenile male wildtype mice (St8sia2(+/+)) (7mg/kg every other day over 3 weeks) did not appreciably affect cognition. St8sia2(-/-) mice, however, displayed a synergistic negative consequence of Δ9-THC on learning/memory, accompanied by polysialic acid-free NCAM-180 reduction in hippocampus and polysialic acid increase in dentate outer molecular layer. These synergistic effects became obvious only months after the last Δ9-THC. We conclude that juvenile cannabis exposure may cause delayed but lasting damage on cognition in subjects genetically predisposed to altered NCAM polysialylation. Copyright © 2014 Elsevier B.V. All rights reserved.

Reflexões bioéticas sobre a eutanásia a partir de caso paradigmático

OpenAIRE

Santos, Daniel Abreu; Almeida, Eduardo Robatto Plessim de; Silva, Felipe Freire da; Andrade, Layo Henrique Carvalho; Azevêdo, Leandro Anton de; Neves, Nedy Maria Branco Cerqueira

2014-01-01

Recentemente, na cidade de Curitiba/PR, ocorreu um fato que gerou grande repercussão nacional e suscitou questões acerca da "eutanásia", tema controverso e pouco debatido na população em geral, o que motivou a realização deste artigo. O objetivo do trabalho consiste em analisar aspectos envolvidos no processo de morrer: eutanásia e ortotanásia e sua relação com o princípio bioético da autonomia. Trata-se de revisão reflexiva de literatura tendo como base matéria publicada na imprensa, abordan...

Proceedings of the CanSIA solar conference 2008

International Nuclear Information System (INIS)

2008-01-01

The Canadian Solar Industries Association (CanSIA) promotes activities directed at improving and accelerating the widespread use of solar energy in Canada. It works to strengthen the Canadian solar industry by ensuring that governments in Canada understand the contribution that a viable solar equipment industrial base can make to Canada's industrial and social development. CanSIA helps its members in the development of product standards and building codes for the solar equipment industry, with special emphasis of safety, performance, and economic impact. The first session of the conference discussed the legal, financial and technical issues involved in capturing and capitalizing on the carbon emission reduction potential of solar projects. The second session addressed community buying issues with particular reference to matching homeowner and industry interests. Some presentations highlighted the research programs underway at universities and companies across Canada to identify the latest, most advanced and efficient technology that offers energy solutions. The barriers that the solar industry faces as it tries to deploy solar energy were also reviewed along with possible ways to overcome these barriers in ways that suit governments and local communities. The conference featured 20 presentations, of which 3 have been catalogued separately for inclusion in this database. tabs., figs

Mārketinga komunikāciju analīze uzņēmumā SIA "Adidas Baltics".

OpenAIRE

Zvīnis, Gusts Gustavs

2017-01-01

Bakalaura darba tēma ir “Mārketinga komunikāciju analīze uzņēmumā Sia “adidas Baltics” Darba mērķis ir pamatojoties uz apkopoto teorētiskās daļas informāciju par mārketinga komunikāciju veidiem un to plānošanu , analizēt uzņēmuma Sia “adidas Baltics” mārketinga komunikāciju efektivitāti Latvijas tirgū, rezultātā izstrādājot rekomendācijas uzņēmuma Sia “adidas Baltics” mārketinga komunikāciju efektivitātes palielināšanai. Bakalaura darbs sastāv no ievada, piecām nodaļām, secinājumiem un prie...

SIA "Emīla Gustava šokolāde" šokolādes kvalitāte.

OpenAIRE

Balcere, Marika

2007-01-01

Bakalaura darba tēmas nosaukums ir SIA „Emīla Gustava Šokolāde” šokolādes kvalitāte. Darba autore darba tēmu izvēlējās, jo ir strādājusi SIA „Emīla Gustava Šokolāde”, kā arī vēlējās gūt apstiprinājumu par izteikumu, ka SIA „Emīla Gustava Šokolāde” šokolāde ir ekskluzīva un izsmalcināta. Darba mērķis: iepazīties ar šokolādes kvalitāti. Darbs sastāv no divām daļām - teorētiskās un empīriskās daļas. 1. nodaļā aprakstīta šokolādes produktu attīstības vēsture. 2. nodaļā aprakstīta...

A simple and economic slide micro-immunoenzymatic (Micro-SIA test for epidemiological studies of toxoplasmosis

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Mara Rosenzvit

1994-03-01

Full Text Available A slide micro-immunoenzymatic assay (micro-SIA to detectantibodies to non-particulate Toxoplasma gondii antigens is described. This assay allows the diagnosis of toxoplasmosis infection in about 1 hr. Twenty-four determinations can be performed per slide. Five hundred ng of antigen and 5 or 10 µl drop of each reactive are necessary per well. The clear contrast of colours obtained for negative and positive sera after the test is finished, allows direct discrimination of the results. However, it is possible to quantify the results of the reaction using a minireader. Sera dilution cutoff value, determined as themost frequent titre for the general population, is 1:100. The toxoplasma micro-SIA correlates well with indirect immunofluorescence (IIF, its sensitivity is atleast three times as much as IIF. The test has an intra and inter assay variation coefficient of 5.46 per cent and of 6.24 per cent respectively. Sera obtained at random from argentinian people were analyzed and a 56 per cent of infection was found. The main features of the Toxoplasma micro-SIA are its simplicity, sensitivity, reproducibility, and the virtual absence of background making it very suitable for screening tests.

ToSIA-A tool for sustainability impact assessment of forest-wood-chains

NARCIS (Netherlands)

Lindner, M.; Suominen, T.; Palosuo, T.; Garcia-Gonzalo, J.; Verweij, P.J.F.M.; Zudin, S.; Päivinen, R.

2010-01-01

Within the forest sector, the sustainability concept has evolved from a narrow focus on sustainable wood production to a much broader evaluation of environmental, social, and economic sustainability for whole value chains. A new software tool – ToSIA – has been developed for assessing sustainability

Starptautiskais mārketings SIA „NEW ROSME” uzņēmumā

OpenAIRE

Rodčenkova, Anastasija

2014-01-01

Atslēgas vārdi: ienākšanas veidi starptautiskā tirgū; franšīze; franšīzes metodes priekšrocības un trūkumi; Krievijas Federācijas apakšveļas tirgus. Bakalaura darbs sastāv no 66 lappusēm, neieskaitot pielikumus, 21 attēliem, 2 tabulām, 2 pielikumiem. Pētījuma procesā tika izmantoti 46 literatūras un informācijas avoti. Bakalaura darba temats ir „Franšīze kā uzņēmuma SIA „NEW ROSME” attīstības stratēģija Krievijas tirgū”. Darba mērķis ir izpētīt uzņēmuma SIA „NEW ROSME” franšīzes metodes...

Eutanásia: novas considerações penais

OpenAIRE

Marcello Ovidio Lopes Guimarães

2009-01-01

Consiste o trabalho em tela na proposição de um estudo da eutanásia em seus variados aspectos, que se refletem em amplos e distintos setores do conhecimento humano, sejam eles filosóficos, religiosos, históricos, culturais, sociológicos, políticos e, particularmente, jurídicos. O estudo é iniciado com a noção geral sobre o tema eutanásico, procurando-se apresentar definições trazidas por autores dos mais diferentes matizes, na busca de uma definição que permita à norma legal amoldar-se ao con...

Variants of ST8SIA1 are associated with risk of developing multiple sclerosis.

Directory of Open Access Journals (Sweden)

Seema Husain

Full Text Available Multiple sclerosis (MS is an inflammatory demyelinating disease of the central nervous system of unknown etiology with both genetic and environmental factors playing a role in susceptibility. To date, the HLA DR15/DQ6 haplotype within the major histocompatibility complex on chromosome 6p, is the strongest genetic risk factor associated with MS susceptibility. Additional alleles of IL7 and IL2 have been identified as risk factors for MS with small effect. Here we present two independent studies supporting an allelic association of MS with polymorphisms in the ST8SIA1 gene, located on chromosome 12p12 and encoding ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1. The initial association was made in a single three-generation family where a single-nucleotide polymorphism (SNP rs4762896, was segregating together with HLA DR15/DQ6 in MS patients. A study of 274 family trios (affected child and both unaffected parents from Australia validated the association of ST8SIA1 in individuals with MS, showing transmission disequilibrium of the paternal alleles for three additional SNPs, namely rs704219, rs2041906, and rs1558793, with p = 0.001, p = 0.01 and p = 0.01 respectively. These findings implicate ST8SIA1 as a possible novel susceptibility gene for MS.

Do Si/As ratios in growth medium affect arsenic uptake, arsenite efflux and translocation of arsenite in rice (Oryza sativa)?

Science.gov (United States)

Zhang, Min; Zhao, Quanli; Xue, Peiying; Zhang, Shijie; Li, Bowen; Liu, Wenju

2017-10-01

Silicon (Si) may decrease the uptake and accumulation of arsenic (As) in rice. However, the effects of Si/As ratios in growth medium on arsenic uptake, arsenite efflux to the external medium and translocation of arsenite in rice are currently unclear. Rice seedlings (Oryza sativa L.) were exposed to nutrient solutions with 10 μM arsenite [As(III)] or 10 μM arsenate [As(V)] to explore the influence of different silicic acid concentrations (0, 10, 100, 1000 μM) on arsenic uptake and translocation of arsenite with or without 91 μM phosphate for 24 h. Arsenic speciation was determined in nutrient solutions, roots, and shoots. In the arsenite treatments, different Si/As ratios (1:1, 10:1, 100:1) did not affect As(III) uptake by rice roots, however they did inhibit translocation of As(III) from roots to shoots significantly (P rice roots and shoots. A Si/As ratio of 100:1 reduced As(III) translocation from roots to shoots markedly without phosphate. When phosphate was supplied, As(III) translocation from roots to shoots was significantly inhibited by Si/As ratios of 10:1 and 100:1. The results indicated that in the presence of P, different silicic acid concentrations did not impact arsenite uptake and transport in rice when arsenite was supplied. However, a Si/As ratio of 100:1 inhibited As(V) uptake, as well as As(III) efflux and translocation from roots to shoots when arsenate was supplied. Copyright © 2017 Elsevier Ltd. All rights reserved.

SIA „Lattelecom Technology” darbība „DELL” produktu sadales kanālā.

OpenAIRE

Zēmele, Lāsma

2009-01-01

L. Zēmele SIA „Lattelecom Technology” darbība „DELL” produktu sadales kanālā Bakalaura darbs saturs:82 lpp, 10 tabulas, 16 attēlu un 16 pielikumu Bakalaura darbā raksturota SIA „Lattelecom Technology” darbība „DELL” produktu sadales kanālā. Darbā tiek analizēta produktu plūsma sadales kanālā, pasūtīšanas, uzglabāšanas un transportēšanas funkciju realizēšana šajā sadales kanālā, kā arī klientu apmierinātība ar uzņēmuma piedāvātajiem pakalpojumiem. Balstoties uz latviešu un ārzemj...

SIA skandaali neli patust - täna kõvemad kui 10 aastat tagasi / Jaanus Piirsalu

Index Scriptorium Estoniae

Piirsalu, Jaanus, 1973-

2005-01-01

1995. aasta oktoobris aset leidnud lindiskandaalist ja selle osalistest. Vt. samas: SIA skandaal ja järgnenud valitsuskriis; Väljavõte stenogrammist; Meelak: paljud ihkasid kohtus näha Savisaare verd

SIA "Baltegle" naudas plūsmas analīze un vadīšana

OpenAIRE

Jegorova, Valērija

2011-01-01

Vairākiem Latvijas uzņēmumiem ir aktuālas stabilizēšanas problēmas, kuras ietekmēja naudas plūsmas neefektīva vadīšana. Diplomdarba mērķis ir novērtēt SIA „Baltegle” naudas plūsmu un izstrādāt priekšlikumus tās optimizācijai. Pirmajā diplomdarba nodaļā apskatīta naudas plūsmas būtība, otrajā nodaļā - naudas plūsmas pārskata sagatavošanas īpatnības, trešajā nodaļā - analīzes un vadīšanas aspekti. Ceturtajā nodaļā pētīta SIA „Baltegle” saimnieciskā darbība. Piektajā nodaļā veikta uzņēmuma...

Dysthanasia, euthanasia, orthotanasia: the perceptions of nurses working in intensive care units and care implications Distanasia, eutanasia y ortotanasia: percepciones de los enfermeros de unidades de terapias intensiva e implicaciones en la asistencia Distanásia, eutanásia e ortotanásia: percepções dos enfermeiros de unidades de terapia intensiva e implicações na assistência

Directory of Open Access Journals (Sweden)

Chaiane Amorim Biondo

2009-10-01

,81% supieron citarlos. El fundamento para actuar profesionalmente, entre los enfermeros, no fue homogéneo y el conocimiento acerca del tema todavía es limitado. La búsqueda por la ortotanasia, los principios bioéticos y la humanización de la asistencia deberían ser fundamentos de su asistencia.Os objetivos deste estudo foram analisar as percepções dos enfermeiros que atuam em UTI de um hospital universitário, no Brasil, sobre distanásia, ortotanásia e eutanásia e caracterizar as possíveis implicações na assistência. Trata-se de pesquisa com abordagem quantitativa, aplicando-se questionário em 27 enfermeiros, após autorização do Comitê de Ética da Instituição e aceite formal dos sujeitos. Nenhum enfermeiro soube conceituar eutanásia, metade conceituou distanásia e apenas um terço a ortotanásia. Do total, 65,39% reconhecem algum desses processos em sua prática diária, 25,9% afirmam não acreditar que o enfermeiro pode contribuir sabendo desses conceitos e sua aplicabilidade, 82,36% relataram ser importante saber os princípios bioéticos, mas somente 14,81% souberam citá-los. O fundamento do agir profissional dos enfermeiros não foi homogêneo e o conhecimento acerca do tema ainda é limitado. A busca pela ortotanásia, os princípios bioéticos e a humanização da assistência deveriam ser fundamentos de sua assistência.

The Social Interaction Anxiety Scale (SIAS) and the Social Phobia Scale (SPS): a comparison of two short-form versions.

Science.gov (United States)

Fergus, Thomas A; Valentiner, David P; Kim, Hyun-Soo; McGrath, Patrick B

2014-12-01

The widespread use of Mattick and Clarke's (1998) Social Interaction Anxiety Scale (SIAS) and Social Phobia Scale (SPS) led 2 independent groups of researchers to develop short forms of these measures (Fergus, Valentiner, McGrath, Gier-Lonsway, & Kim, 2012; Peters, Sunderland, Andrews, Rapee, & Mattick, 2012). This 3-part study examined the psychometric properties of Fergus et al.'s and Peters et al.'s short forms of the SIAS and SPS using an American nonclinical adolescent sample in Study 1 (N = 98), American patient sample with an anxiety disorder in Study 2 (N = 117), and both a South Korean college student sample (N = 341) and an American college student sample (N = 550) in Study 3. Scores on both sets of short forms evidenced adequate internal consistency, interitem correlations, and measurement invariance. Scores on Fergus et al.'s short forms, particularly their SIAS short form, tended to capture more unique variance in scores of criterion measures than did scores on Peters et al.'s short forms. Implications for the use of these 2 sets of short forms are discussed. (c) 2014 APA, all rights reserved.

As viagens de Nísia Floresta: memória, testemunho e história The travels of Nísia Floresta: memory, testimony, and history

OpenAIRE

Constância Lima Duarte

2008-01-01

Dentre os escritores brasileiros do século XIX, que registraram suas viagens em livros, destaca-se Nísia Floresta Brasileira Augusta. Nascida no interior do Rio Grande do Norte, em 1810, ela residiu em Pernambuco, Rio Grande do Sul e Rio de Janeiro antes de se mudar para a Europa, em 1849, e visitar diferentes países até falecer, em 1885, em Rouen, na França. Dos 15 títulos que publicou - romance, novela, contos, poemas e ensaios, escritos em português, francês e italiano -, estão os interess...

As viagens e o discurso autobiográfico de Nísia Floresta

Directory of Open Access Journals (Sweden)

Constância Lima Duarte

2009-12-01

Full Text Available Nos livros em que registrou suas viagens pela Europa, Nísia Floresta deixou também, ao lado de reflexões sobre as novas culturas, depoimentos importantes da própria vida. Aliás, praticamente tudo o que se sabe hoje sobre a autora foi encontrado em seus livros, independente deles serem poemas, romances, crônicas ou ensaios, tal o caráter autobiográfico de sua obra. Para este momento, tratarei de um dos livros de viagem: o Itinerário de uma viagem à Alemanha, escrito em francês e publicado em Paris, em 1857. Em seu relato, Nísia Floresta vai privilegiar não a história da cidade que visita, mas a própria subjetividade, ou seja, as emoções que os objetos e os lugares lhe despertam. Através da memória, ela busca reminiscências da infância, ou vai ao encontro de familiares distantes, estejam eles vivos ou não, como forma de novamente re-viver momentos de felicidade. A narradora se coloca no centro da escritura, se auto contempla romanticamente, e tudo o mais parece girar à sua volta.

Clinical validation of a non-heteronormative version of the Social Interaction Anxiety Scale (SIAS)

OpenAIRE

Lindner, Philip; Martell, Christopher; Bergström, Jan; Andersson, Gerhard; Carlbring, Per

2013-01-01

Introduction: Despite welcomed changes in societal attitudes and practices towards sexual minorities, instances of heteronormativity can still be found within healthcare and research. The Social Interaction Anxiety Scale (SIAS) is a valid and reliable self-rating scale of social anxiety, which includes one item (number 14) with an explicit heteronormative assumption about the respondents sexual orientation. This heteronormative phrasing may confuse, insult or alienate sexual minority responde...

Characterization of SiaA, a streptococcal heme-binding protein associated with a heme ABC transport system.

Science.gov (United States)

Sook, Brian R; Block, Darci R; Sumithran, Suganya; Montañez, Griselle E; Rodgers, Kenton R; Dawson, John H; Eichenbaum, Zehava; Dixon, Dabney W

2008-02-26

Many pathogenic bacteria require heme and obtain it from their environment. Heme transverses the cytoplasmic membrane via an ATP binding cassette (ABC) pathway. Although a number of heme ABC transport systems have been described in pathogenic bacteria, there is as yet little biophysical characterization of the proteins in these systems. The sia (hts) gene cluster encodes a heme ABC transporter in the Gram positive Streptococcus pyogenes. The lipoprotein-anchored heme binding protein (HBP) of this transporter is SiaA (HtsA). In the current study, resonance Raman (rR), magnetic circular dichroism (MCD), and nuclear magnetic resonance (NMR) spectroscopies were used to determine the coordination state and spin state of both the ferric and ferrous forms of this protein. Identifiers from these techniques suggest that the heme is six-coordinate and low-spin in both oxidation states of the protein, with methionine and histidine as axial ligands. SiaA has a pKa of 9.7 +/- 0.1, attributed to deprotonation of the axial histidine. Guanidinium titration studies show that the ferric state is less stable than the ferrous state, with DeltaG(H2O) values for the oxidized and reduced proteins of 7.3 +/- 0.8 and 16.0 +/- 3.6 kcal mol-1, respectively. The reductive and oxidative midpoint potentials determined via spectroelectrochemistry are 83 +/- 3 and 64 +/- 3 mV, respectively; the irreversibility of heme reduction suggests that redox cycling of the heme is coupled to a kinetically sluggish change in structure or conformation. The biophysical characterization described herein will significantly advance our understanding of structure-function relationships in HBP.

Percepção de enfermeiros intensivistas sobre distanásia em unidade de terapia intensiva Intensivist nurses perception of intensive care unit dysthanasia

Directory of Open Access Journals (Sweden)

Fernando Salomão da Silva

2009-06-01

Full Text Available OBJETIVO: Identificar e analisar a percepção de enfermeiros da unidade de terapia intensiva de um hospital escola em Londrina sobre distanásia em pacientes terminais na unidade de terapia intensiva. MÉTODOS: Estudo de natureza qualitativa. Os dados foram coletados por meio de entrevista semi-estruturada gravada, com nove enfermeiros das unidades de terapia intensiva de um hospital escola, no mês de janeiro de 2009. Foi utilizada a análise temática para analisar os discursos dos sujeitos e identificar as categorias de discussão. RESULTADOS: Foram identificadas cinco categorias que foram discutidas com base na experiência dos autores e na literatura, sendo elas: medidas que prolongam a vida do paciente fora de possibilidade de cura na unidade de terapia intensiva; ações/reações dos enfermeiros diante da distanásia; motivos que levam ao prolongamento da vida de pacientes fora de possibilidade de cura; sentimentos dos enfermeiros sobre a distanásia e prolongamento da vida; medidas de cuidado em oposição à distanásia. CONCLUSÃO: A vivência dos enfermeiros perante as ações de distanásia mostrou-se complexa, sendo um fator de sofrimento, frustração a inquietação para estes profissionais. A falta de comunicação destaca-se como fator importante na visão dos enfermeiros para a ocorrência de distanásia e a medida para substituir a distanásia são os cuidados que proporcionam alivio do sofrimento.PURPOSE: Identify and evaluate the perception of Intensivist Nurses in a University Hospital in Londrina, of dysthanasia in terminal patients at the Intensive Care Unit. METHODS: Qualitative study. Data were collected by semi-structured recorded interview involving nine nurses working in a university hospital intensive care units, during January 2009. A thematic analysis was used to evaluate subjects' speech and identify discussion categories. RESULTS: Five categories were identified, discussed based on the authors' experience and

Factor solutions of the Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS) in a Swedish population.

Science.gov (United States)

Mörtberg, Ewa; Reuterskiöld, Lena; Tillfors, Maria; Furmark, Tomas; Öst, Lars-Göran

2017-06-01

Culturally validated rating scales for social anxiety disorder (SAD) are of significant importance when screening for the disorder, as well as for evaluating treatment efficacy. This study examined construct validity and additional psychometric properties of two commonly used scales, the Social Phobia Scale and the Social Interaction Anxiety Scale, in a clinical SAD population (n = 180) and in a normal population (n = 614) in Sweden. Confirmatory factor analyses of previously reported factor solutions were tested but did not reveal acceptable fit. Exploratory factor analyses (EFA) of the joint structure of the scales in the total population yielded a two-factor model (performance anxiety and social interaction anxiety), whereas EFA in the clinical sample revealed a three-factor solution, a social interaction anxiety factor and two performance anxiety factors. The SPS and SIAS showed good to excellent internal consistency, and discriminated well between patients with SAD and a normal population sample. Both scales showed good convergent validity with an established measure of SAD, whereas the discriminant validity of symptoms of social anxiety and depression could not be confirmed. The optimal cut-off score for SPS and SIAS were 18 and 22 points, respectively. It is concluded that the factor structure and the additional psychometric properties of SPS and SIAS support the use of the scales for assessment in a Swedish population.

A eutanásia na visão do garantismo penal

OpenAIRE

Reicher, Regina Maria

2005-01-01

Num cotejo entre a eutanásia e o garantismo de Luigi Ferrajoli, quanto à proibição penal, os princípios da lesividade e necessidade, e o direito penal mínimo, este estudo faz uma projeção sobre as principais conseqüências desse comportamento em matéria penal, notadamente quanto à sua repercussão sobre o princípio da dignidade da pessoa humana, que é corolário lógico do Estado Democrático de Direito. Não se justifica, no modelo de direito penal mínimo propugnado pelo garantismo, a penalizaç...

HES and T'Sou-ke Nation awarded CanSIA solar project of the year

Energy Technology Data Exchange (ETDEWEB)

Anon.

2010-01-15

Home Energy Solutions (HES) has installed the largest solar photovoltaic solar array in British Columbia. In 2009, the Sum-SHA-Thut installation won the award for the Solar Project of the Year by the Canadian Solar Industries Association (CanSIA). It was built for Vancouver Island's T'Sou-ke Nation and its success shows great promise for solar electric generation in Canada. Energy consumption has decreased 30 per cent since the installation in July 2009, making the T'Sou-ke First Nation the most solar-intensive nation per capita in the world. The solar community project demonstrates that as a clean, renewable source of energy, solar electricity is a real solution for climate change, both internationally and at a local level. The timing of the CanSIA award is significant for the Canadian solar industry, falling in the midst of the Copenhagen Climate Change Conference and just shortly after Ontario introduced its micro feed-in-tariff program for renewable energy technologies. The project also demonstrates British Columbia's leadership in the alternative energy sector, and how solar can play a significant role in the future energy supply. 1 fig.

Projekts: SIA Ģimenes centrs" dibināšana

OpenAIRE

Mensaha, Elizabete

2016-01-01

Maģistra darba tēma ir projekts SIA „Ģimenes centrs” dibināšana. Ikviena cilvēka dzīvē ģimene ir pati svarīgākā. Ģimenē veidojas galvenie uzskati par to, kas ir labi vai slikti, pareizi vai nepareizi, godīgi vai negodīgi. Bērni, kuri jau no bērnības dzīvo labvēlīgās ģimenēs, zina, kā veidot labas attiecības savā un savu bērnu ģimenē, zina, kā pārvarēt sadzīviskas vai ikdienišķas problēmas, kuras bieži kļūst par ģimenes šķiršanās iemesliem. Laulības šķiršana ir viena no aktuālākajām mūsdienas ...

SIA "Valrito" apgrozījuma palielināšana

OpenAIRE

Lazdiņš, Ivars

2014-01-01

Maģistra darba mērķis ir izpētīt SIA „Valrito” attīstības iespējas, piedāvājot savam klientam iegādāties jaunu, līdz šim nepiedāvātu produktu līdz 2015. gadam, pielietojot projekta vadīšanas metodes.Darbs ietver uzņēmuma veikalu „Gustiņš” noieta tirgus, produktu un pakalpojumu piedāvājuma, un finanšu rādītāju izpēti, un analīzi. Risinājuma piedāvājumu, kura realizācijai par pamatu tiks ņemts jauna produkta ražošanas uzsākšana.Darba pētījuma ietvaros tiek definēta sekojoša problēma: Uzņēmums ...

Bioloģisko aktīvu uzskaite SIA "Lielvircava Agro"

OpenAIRE

Laščenko, Jeļena

2010-01-01

Latvijā bioloģisko aktīvu uzskaites problemātika ir neizpētīts jautājums, gan no zinātnisko pētījumu, gan no regulējuma aspekta. Darba mērķis ir izpētīt SIA „Lielvircava AGRO” piederošo bioloģisko aktīvu uzskaites īpatnības un izstrādāt priekšlikumus bioloģisko aktīvu uzskaites pilnveidošanai. Darba mērķi un uzdevumi tiek atspoguļoti darba divās loģiski saistītās nodaļās, secinājumos un priekšlikumos, literatūras sarakstā, kā arī pielikumos. Darba pirmā nodaļā tiek skaidrots bioloģis...

Two particle correlations at mid-rapidity in Si+A and Au+Au from E859/E866

International Nuclear Information System (INIS)

Baker, M.D.

1997-01-01

Two particle correlation measurements for Si-A and Au- Au collisions from Brookhaven E859 and E866 are discussed. These measurements allow us, with some interpretation, to deduce the size of the participant region in a heavy ion collision. We show that various source parameterizations yield consistent results and we explore the dependence of the apparent source size on the pion yield

A análise por injeção sequencial (SIA: vinte anos em uma perspectiva brasileira

Directory of Open Access Journals (Sweden)

Allan Cezar Vieira dos Santos

2010-01-01

Full Text Available The year of 2010 marks the 20th anniversary of the development of Sequential Injection Analysis (SIA by Ruzicka and Marshall. Considered the second generation of the flow injection methods, this article briefly describes the history, the basic principles of the technique and reviews all papers developed by Brazilian scientists aiming the divulgation of this automation technique in Analytical Chemistry.

Characterization of the N-Acetyl-5-neuraminic Acid-binding Site of the Extracytoplasmic Solute Receptor (SiaP) of Nontypeable Haemophilus influenzae Strain 2019

Energy Technology Data Exchange (ETDEWEB)

Johnston, Jason W.; Coussens, Nathan P.; Allen, Simon; Houtman, Jon C.D.; Turner, Keith H.; Zaleski, Anthony; Ramaswamy, S.; Gibson, Bradford W.; Apicella, Michael A. (Iowa); (Buck Inst.)

2012-11-14

Nontypeable Haemophilus influenzae is an opportunistic human pathogen causing otitis media in children and chronic bronchitis and pneumonia in patients with chronic obstructive pulmonary disease. The outer membrane of nontypeable H. influenzae is dominated by lipooligosaccharides (LOS), many of which incorporate sialic acid as a terminal nonreducing sugar. Sialic acid has been demonstrated to be an important factor in the survival of the bacteria within the host environment. H. influenzae is incapable of synthesizing sialic acid and is dependent on scavenging free sialic acid from the host environment. To achieve this, H. influenzae utilizes a tripartite ATP-independent periplasmic transporter. In this study, we characterize the binding site of the extracytoplasmic solute receptor (SiaP) from nontypeable H. influenzae strain 2019. A crystal structure of N-acetyl-5-neuraminic acid (Neu5Ac)-bound SiaP was determined to 1.4 {angstrom} resolution. Thermodynamic characterization of Neu5Ac binding shows this interaction is enthalpically driven with a substantial unfavorable contribution from entropy. This is expected because the binding of SiaP to Neu5Ac is mediated by numerous hydrogen bonds and has several buried water molecules. Point mutations targeting specific amino acids were introduced in the putative binding site. Complementation with the mutated siaP constructs resulted either in full, partial, or no complementation, depending on the role of specific residues. Mass spectrometry analysis of the O-deacylated LOS of the R127K point mutation confirmed the observation of reduced incorporation of Neu5Ac into the LOS. The decreased ability of H. influenzae to import sialic acid had negative effects on resistance to complement-mediated killing and viability of biofilms in vitro, confirming the importance of sialic acid transport to the bacterium.

Passado e presente: Sicília e Mileto, Roma e Afrodísias no romance de Cáriton

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Adriane da Silva Duarte

2016-03-01

Full Text Available Quéreas e Calírroe, romance de Cáriton de Afrodísias (I d.C., tem como ponto de partida e de retorno do par protagonista a cidade de Siracusa, na Sicília do início do século IV a.C.. Uma parte considerável da ação, contudo, se passa em Mileto, para onde se desloca a heroína. Procura-se investigar aqui as razões dessa opção de Cáriton, que já na primeira sentença de sua obra proclama sua nacionalidade, alertando o leitor que o autor é um grego que vive na periferia do império romano. A hipótese é que a escolha por situar a ação do romance no passado reflita menos a emulação do relato historiográfico, especialmente o de Tucídides, mas antes uma estratégia para tratar indiretamente da relação entre Afrodísias e Roma no presente.

Training activities and perspectives in the radioactive waste management area of Moscow SIA 'Radon' - 16131

International Nuclear Information System (INIS)

Batyukhnova, O.G.; Arustamov, A.E.; Dmitriev, S.A.; Arustamova, N.A.; Ojovan, M.; Drace, Z.

2009-01-01

The education service for specialists dealing with radioactive waste was established in Russia (former USSR) in 1983 and was based on the capabilities of two organisations: Moscow Scientific and Industrial Association 'Radon' (SIA 'Radon') and Lomonosov's Moscow State University. These two organizations are able jointly to offer training programs in the science fundamentals, applied research and in practical operational areas of the all pre-disposal activities of the radioactive waste management (RWM). Since 1997 this system was upgraded to the international level and now acts as the International Education Training Centre (IETC) at SIA 'Radon' under the guidance of the IAEA. During last 12 years more than 350 specialists from 33 European and Asian countries enhanced their knowledge and skills in RWM. The IAEA supported many specialized regional training courses and workshops, fellowships, on-the-job training, and scientific visits which are additional means to assure development of personnel capabilities. Efficiency of training was analysed at IETC using the structural adaptation of educational process as well as factors, which have influence on education quality. In addition social-psychological aspects were also taken into account in assessing the overall efficiency. The analysis of the effect of individual factors and the efficiency of education activity were carried out based on appraisal results and post-course questioning of attendees. (authors)

Mid-term evaluation of the Climate Change Action Fund: Science, Impacts and Adaptation (SIA) block

International Nuclear Information System (INIS)

2001-11-01

In 1998, the Climate Change Action Fund was established by the Government of Canada. Its budget represented 150 million dollars over a three year period, and was an additional 625 million dollars in the federal budget of February 2000 was allocated for climate change initiatives, of which 150 million dollars were earmarked over a three year period to the Climate Change Action Fund. To provide input for Treasury Board Submissions looking for funding approval in the future, it was necessary to conduct a mid-term evaluation focused on program performance to date. The period covered by the evaluation was September 2000 to the end of January 2001. This report examined the performance of the Science, Impact and Adaptation Block (SIA). Based on a series of interviews with representatives of Block managers, Technical and Executive Policy Committees, successful applicants, unsuccessful applicants and peer reviewers, as well as a review of the documentation maintained by SIA, it addressed the following issues: Block relevance, progress/success to date, and effectiveness in meeting the objectives. It was determined that the objectives displayed relevance to the climate change agenda of the federal government, progress to date was considered satisfactory, and most of the objectives should be met in a timely fashion. A summary of the findings was included in this document along with recommendations pertaining to the findings. 3 tabs., 1 fig

Measurements of T0 temperatures of supersaturated Si-As alloys

International Nuclear Information System (INIS)

Lee, K.R.; West, J.A.; Smith, P.M.; Aziz, M.J.

1992-01-01

In this paper the congruent melting point, or T 0 curve, of crystalline Si-As alloys has been measured in the range of 1.6 to 18.1 at.% arsenic by line source electron beam annealing. Alloys were created by ion implantation of as into 0.1 mm Si-on-sapphire and crystallized by pulsed laser melting. T 0 temperatures decrease form 1673 ± 10K at 2.0 at.% As to 1516 ± 30K at 18.1 at.% As. The results of these measurements are significantly higher than the previous results of studies using pulsed laser melting techniques. Advantages of the e-beam technique over previous techniques are discussed. Chemical free energy functions of the solid and liquid phases were calculated from existing thermodynamic data. The calculated T 0 curve agrees with the measured values only in low concentration region (less than 8 at.%)

Dysthanasia: nursing professionals' perception Distanasia: percepción de los profesionales de enfermería Distanásia: percepção dos profissionais da enfermagem

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Milene Barcellos de Menezes

2009-08-01

Full Text Available Dysthanasia means slow and painful death without quality of life. This study aimed to know whether nurses identify dysthanasia as part of the final process of the lives of terminal patients hospitalized at an adult ICU. This is an exploratory-qualitative study. Data were collected through semi-structured interviews with ten nurses with at least one year of experience in an ICU, and interpreted through content analysis. Results indicate that nurses understand and identify dysthanasia, do not agree with it and recognize elements of orthonasia as the adequate procedure for terminal patients. We conclude that nurses interpret dysthanasia as extending life with pain and suffering, while terminal patients are submitted to futile treatments that do not benefit them. They also identify dysthanasia using elements of orthonasia to explain it.Distanasia significa muerte lenta, con sufrimiento y sin calidad de vida. En esta investigación se buscó conocer si los enfermeros identifican la distanasia como parte del proceso final de la vida de personas en estado terminal, internadas en una UTI para adultos. El estudio es de naturaleza exploratoria, con abordaje cualitativo. Los datos fueron recolectados por medio de entrevista semiestructurada con 10 enfermeros con un mínimo de un año de experiencia en UTI; los datos fueron interpretados por el análisis de contenido. Se obtuvo como resultado que los enfermeros comprenden e identifican la distanasia y se oponen a la misma, presentando elementos de ortotanasia como procedimiento adecuado para pacientes en estado terminal. Se concluye que los enfermeros interpretan la distanasia como el prolongamiento de la vida con dolor y sufrimiento, en el cual los pacientes terminales son sometidos a tratamientos fútiles que no traen beneficios. También identifican la distanasia, usando elementos de la ortotanasia para hacerla explicita.Distanásia significa morte lenta, sofrida e sem qualidade de vida. Nesta pesquisa

Iseäraliku väega piigad, õhupallimeelast karust rääkimata / Anneli Aasmäe

Index Scriptorium Estoniae

Aasmäe, Anneli, 1973-

2001-01-01

6. septembril Coca-Cola Plazas esilinastuva Arvo Iho mängufilmi "Karu süda" peategelast Niikat mängiva Rain Simmuli abiga meenutatakse filmimist ja kaasnäitlejaid Dinara Drukarovat, Iljana Pavlovat ja karu Malõshshi

Automated washing of FTA Card punches and PCR setup for reference samples using a LIMS-controlled Sias Xantus automated liquid handler

DEFF Research Database (Denmark)

Stangegaard, Michael; Olsen, Addie Nina; Frøslev, Tobias G.

2009-01-01

We have implemented and validated automated methods for washing FTA Card punches containing buccal samples and subsequent PCR setup using a Sias Xantus automated liquid handler. The automated methods were controlled by worklists generated by our LabWare Laboratory Information Management System...

Lingots et couteaux en fer d'Alésia. Études archéométriques de pièces inédites

Czech Academy of Sciences Publication Activity Database

Pleiner, Radomír; Fluzin, P.; Mangin, M.; Billon, M.; Dillmann, P.; Vega, E.; Rabeisen, E.

2003-01-01

Roč. 52, - (2003), s. 91-130 ISSN 1266-7706 Institutional research plan: CEZ:AV0Z8002910 Keywords : lingots * knives * metallography * oppidum * Alésia Subject RIV: AC - Archeology, Anthropology, Ethnology

Izmaksu un ieņēmumu klasifikācija un analīze mediju aģentūrā SIA "Carat"

OpenAIRE

Ozoliņa, Evita

2013-01-01

Diplomdarba tēma ir „Izmaksu un ieņēmumu klasifikācija un analīze mediju aģentūrā SIA „Carat””. Katrai Latvijas sabiedrībai (uzņēmumam) ir svarīgi apzināties tās ražošanas izmaksas, veikt šo izmaksu uzskaiti, iegrāmatošanu un turpmāko plānošanu ilgtermiņā. Reklāma ir ietekmīgs sabiedrības preces, pakalpojuma un citu objektu popularizēšanas līdzeklis. Tā kā Latvijā ekonomiskās lejupslīdes gados strauji kritās reklāmas tirgus, darba autorei ir aktuāli raksturot, pētīt un analizēt SIA „Car...

Euthanasia in small animals in Teresina – PI/ Eutanásia em pequenos animais em Teresina – PI

Directory of Open Access Journals (Sweden)

Ezequiel Cardoso Saraiva de Almeida

2005-06-01

Full Text Available Euthanasia is a procedure frequently utilized in small animals with the objective to minimize suffering. In this way, it was realized the survey about reasons that leave the practitioner to realize the procedure and who are these animals. It was analyzed 17406 medical records. It was observed 166 euthanasia corresponding to 0.95%. The percentage of the euthanazied dogs were 97.59% and 2.41% felines. In relation to breed 26.10% were mongrel dogs, 20.48% German sheepherd, 9.04% Brazilian fila, 7.23% Pekinese and 36.75% other breeds. In relation to age, it was observed that 60.84% have 0 – 3 year, 15.06% 3 – 6 year, 4.82% 6 – 9 year, 4.22% 9 – 12 year, 1.2% above 12 year and 13.86% unknown age. About the reason of the euthanasia, 64.60% was sacrificed due to visceral leishmaniosis (calazar, 12.65% due to distemper and 22.89% due to other diseases. It was concluded that the most animals submitted to euthanasia were young, differently of the other countries. Among principal death reasons, it was included also infectious diseases that can be prevented by adequate vaccination.A eutanásia é um procedimento utilizado com freqüência em pequenos animais, com o objetivo principal de aliviar o sofrimento. Desta forma, realizou-se um levantamento sobre os motivos que levam um veterinário a indicá-la e quais são estes animais. Foram analisadas 17406 fichas, onde se observaram 166 eutanásias o que corresponde a 0,95%. A percentagem de cães eutanasiados foi de 97,59% e a de felinos 2,41%. Em relação à raça, 26,10% dos animais era sem raça definida, 20,48% pastor alemão, 9,04% fila brasileiro, 7,23% pequinês e 36, 75% outras raças. Com respeito à idade, registrou-se que 60,84% tinham entre 0 e 3 anos, 15,06% 3 e 6 anos, 4,82% 6 e 9 anos, 4,22% 9 e 12 anos, 1,20% acima de 12 anos e 13,86% idade desconhecida. Sobre o motivo da eutanásia, 64,60% dos animais foram eutanasiados devido à Leishmaniose Visceral Canina (calazar, 12,65% devido a

Amnésia retrógrada funcional grave: relato de caso Severe functional retrograde amnesia: case report

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Maila de Castro L. Neves

2008-01-01

Full Text Available CONTEXTO: Uma síndrome amnésica clássica caracteriza-se por evidente prejuízo da memória anterógrada, variável e temporária amnésia retrógrada, sendo as formas não-declarativas da memória poupadas. Entretanto, publicações recentes relataram casos de prejuízo desproporcional da memória retrógrada em relação à anterógrada. OBJETIVOS: Relatar o caso de um paciente de 26 anos de idade com um quadro grave de amnésia retrógrada, aparentemente sem fatores desencadeantes. MÉTODOS: Entrevista psiquiátrica e avaliação neuropsicológica. RESULTADOS: A perda de memória do paciente se estendia por toda sua vida, mas ele era capaz de adquirir e reter novas informações. Ele também apresentava prejuízos na produção e na compreensão de palavras, assim como no reconhecimento e no uso de objetos. CONCLUSÃO: A formulação diagnóstica final do caso é difícil, apontando possivelmente o contínuo existente entre a amnésia retrógrada psicogênica e a orgânica.BACKGROUND: A classic amnestic syndrome is characterized by a significant impairment of the anterograde memory, a variable and transitory retrograde amnesia with preserved non-declarative memory. However, case reports of patients with disproportionate compromise of the retrograde memory have been described in the recent literature. OBJECTIVES: To report a 26-year-old patient with a severe global retrograde amnesia with no evident triggering factor. METHODS: Psychiatric interview and neuropsychological evaluation. RESULTS: His memory loss compromised all domains of his life, although he could acquire and retain new information. He also exhibited prominent deficits in production and comprehension of common words as well as in recognition and use of objects. DISCUSSION: The final diagnostic formulation of the present case is difficult possibly indicating a continuum between psychogenic and organic retrograde amnesia.

Reservatório de ardósia para sistemas de aproveitamento de água de chuva

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Marcio Antonio Nogueira Andrade

Full Text Available RESUMO No contexto da crescente pressão exercida no mundo todo sobre os recursos hídricos, qualitativa e quantitativamente, o desenvolvimento de tecnologias apropriadas para sistemas de aproveitamento de água de chuva surge como alternativa promissora. Este trabalho tem como principal objetivo apresentar uma tecnologia inovadora para armazenamento de água de chuva, trazendo como modelo a construção de um reservatório executado com placas de ardósia, com capacidade para 250 m3, que faz parte de um sistema de aproveitamento de água de chuva implantado em uma instalação suinícola no Oeste Catarinense. Nesse sistema, a água de chuva é destinada para dessedentação animal e higienização das instalações. Também são apresentados, porém com menos enfoque, os dispositivos de tratamento da água de chuva desenvolvidos no projeto. Realizou-se uma análise comparativa de custos entre esse reservatório e os comumente utilizados na região de estudo. Também foram feitas análises físico-químicas e bacteriológicas da água de chuva em diferentes pontos do sistema, a fim de verificar se a qualidade da água é adequada para os usos pretendidos. A tecnologia de construção de reservatórios de ardósia apresentou rapidez e facilidade de execução e baixo custo de construção. A ardósia, além de servir de forma para a moldagem da armadura e para a argamassagem, é um material natural e abundante na região central do Estado de Santa Catarina. As análises físico-químicas e bacteriológicas mostraram a eficiência dos dispositivos de tratamento da água de chuva aplicados neste trabalho. Por fim, observou-se que a água de chuva é adequada para dessedentação animal, já que atende às condições e padrões para as águas de Classe 3 da Resolução CONAMA 357. Deste modo, a nova tecnologia apresenta grande potencial de aplicação e viabilidade econômica para a região de estudo.

AMPELOGRAPHIC CHARACTERIZATION OF THE AUTOCHTHONOUS GRAPE CULTIVAR “KALLMET” IN MAL��SIA E MADHE, ALBANIA

OpenAIRE

Bardhosh Ferraj; Elisabeta Susaj; Lush Susaj; Irena Kallco

2012-01-01

“Kallmet” is one of the most sprout autochthonous wine grape cultivar in the North-western and Central part of Albania. Study was conducted in three consecutive years, 2009-2011, in Malësia e Madhe, 250 m above the sea level, in the North-western part of Albania, in a 10 years old vineyard. For evaluation of the main characteristics the IPGRI Descriptors of Grapevine was used. Form of the new shoot tip of “Kallmet” is half-open, with no anthocianic coloration, and densely prostrate hairs. The...

SIA „Origami” saimnieciskās darbības analīze

OpenAIRE

Skalbiņš, Verners

2014-01-01

Bakalaura darba tēma ir „SIA „Origami” saimnieciskās darbības analīze”. Darbā apskatītais uzņēmums ir poligrāfijas nozares uzņēmums, kas specializējas lielformāta drukas jomā. Darba mērķis ir identificēt uzņēmuma stiprās un vājās puses, un izstrādāt priekšlikumus tā attīstībai un uzlabošanai. Mērķa sasniegšanai izvirzīti sekojoši uzdevumi: izpētīt uzņēmuma analīzes veikšanai nepieciešamo teorētisko bāzi, uz tās balstoties veikt uzņēmuma analīzi, kā arī izstrādāt secinājumus par līdzšinējo ...

Personnel training experience in the radioactive waste management: 10 years of Moscow SIA 'RADON' international education training centre

International Nuclear Information System (INIS)

Batyukhnova, Olga; Dmitriev, Sergey; Arustamov, Artur; Ojovan, Mikhael

2007-01-01

Available in abstract form only. Full text of publication follows: The education service for specialists dealing with radioactive waste was established in Russia (former USSR) in 1983 and was based on the capabilities of two organisations: the Moscow Scientific and Industrial Association 'Radon' (SIA 'Radon') and the Chemical Department of Lomonosov's Moscow State University. These two organizations are able to offer training programs in the science fundamentals, applied research and in practical operational areas of the all pre-disposal activities of the radioactive waste management. Since 1997 this system was upgraded to the international level and now acts as International Education Training Centre (IETC) at SIA 'Radon' under the guidance of the IAEA. During 10 years more than 300 specialists from 26 European and Asian countries enhanced their knowledge and skills in radioactive waste management. The IAEA supported specialized regional training courses and workshops, fellowships, on-the-job training, and scientific visits are additional means to assure development of personnel capabilities. Efficiency of training was carefully analysed using the structural adaptation of educational process as well as factors, which have influence on education quality. Social-psychological aspects were also taken into account in assessing the overall efficiency. The analysis of the effect of individual factors and the efficiency of education activity were carried out based on attestation results and questioning attendees. A number of analytical methods were utilised such as Ishikawa's diagram method and Pareto's principle for improving of training programs and activities. (authors)

Les tècniques del parlamentarisme racionalitzat en la Constitució de Tunísia de 2014

OpenAIRE

Olivetti, Marco

2015-01-01

La Constitució de Tunísia de 2014, que és el resultat del procés constituent obert l’any 2011, després de la derrota del president Ben Ali, conté una regulació detallada dels òrgans de govern que es distribueixen les funcions de direcció política (Assemblea de Representants del Poble, president de la República, cap del govern); la Constitució regula la formació, el funcionament, les competències d’aquests òrgans i les relacions entre ells. Les característiques més destacades de la forma de go...

Rain Simmul sai mehise näitleja auhinna / Lauri Kärk

Index Scriptorium Estoniae

Kärk, Lauri, 1954-

2002-01-01

Bakuu rahvusvaheline filmilmifestival "Ida-Lääs", kus Rain Simmul sai oma rolli eest Arvo Iho filmis "Karu süda" diplomi. Näidati ka Peeter Simmi mängufilmi "Head käed" ja Andres Maimiku - Jaak Kilmi tõsielufilmi "Isamaa ilu". "Karu süda" on saanud ka Jack Londoni nimelise parima stsenaariumiga filmi auhinna California filmifestivalil Wine Country

Pós 11 de setembro de 2.001 (II – Fortalecimento de novo paradigma de encontro entre civilizações na Ásia-Pacífico

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Paulo Antônio Pereira Pinto

2011-09-01

Full Text Available O presente busca delinear, sob o prisma civilizacional, os rumos das relações entre os países da Ásia-Pacífico a serem tomados após os ataques terroristas de 11 de setembro de 2001.

SIA "Baltic Motors, Ltd" produkti, to attīstības iespējas

OpenAIRE

Silavs, Mārtiņš

2011-01-01

Bakalaura darbā „SIA „Baltic Motors, Ltd produkti, to attīstības iespējas” tiek aplūkota Ford un Mazda automašīnu oficiālā pārstāvja darbība Latvijā, pašreiz sniegto produktu un pakalpojumu nozīmība veiksmīgai nākotnes darbībai, nozares raksturojums, produktu kustība mainīgajos apstākļos. Darba aktualitāti nosaka cilvēku nepieciešamību, uzskatu maiņa ekonomisko apstākļu ietekmē. Darba autors secina, ka cilvēki rūpīgāk izvērtē jaunu produktu iegādi, ir jūtīgi pret cenu izmaiņām, kas jauno a...

Environmental Indicators for Italian Soils (SIAS Project: Development of a New Approach from Regional to Harmonised National Data

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Irene Rischia

2010-10-01

Full Text Available Erosion and loss of organic matter of soils are two of the threats identified by the European Communication “Towards a Thematic Strategy for Soil Protection” (2002/267, and by the Thematic Strategy for Soil Protection (COM 2006, 231. Regarding Italian context, a new approach that exploits soil data and expertise available at local level has been developed in a pilot project, named SIAS Project (Sviluppo Indicatori Ambientali sul Suolo that involves ISPRA (Italian Institute for Environmental Protection and Research as project coordinator and financing body, Regional Agency for Environmental Prevention and Protection in Veneto (ARPAV, responsible of the technical coordination of the activities, Regional Soil Survey Services that contribute to the methodology definition and responsible for the data elaboration within their region of the data, JRC and CRA – ABP as technical support. The SIAS Project concerns the building of two soil environmental indicators, erosion and organic matter content, based on harmonisation of regional data and according with the INSPIRE directive. The main aim of the SIAS Project can be summarised in exploiting at most the existing information and local expertise for indicator assessment in a relatively short time, in order to obtain interregional harmonisation of the information about erosion and organic matter content at regional scale. For this purpose, it has been chosen to assess and represent output data by a reference grid (1 km x 1 km with a common coordinate reference system, following the recommendations of the INSPIRE Directive. Furthermore an exchange format for storing data and metadata information has been set up jointly by the working group. So far a large part of the Northern and Central Italy has completed the project, while a part of Southern Region has only recently joined it. The results show that at the present moment there are some differences both in soil loss and in organic matter content

A prevenção da distanásia nas legislações brasileira e francesa Preventive measures against medical futility in brazilian and french legislations

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Paulo Antonio de Carvalho Fortes

2007-06-01

Full Text Available O texto pretende trazer uma breve reflexão bioética sobre as legislações brasileira e francesa incidentes sobre a distanásia.The text intends to encourage a brief bioethical discussion about medical futility as currently found in Brazilian and French legislations.

Plano de marketing internacional para a indústria metalomecânica no mercado da Indonésia : o caso ADIRA

OpenAIRE

Tedim, Ilda Filipa de Sousa

2015-01-01

Ao longo do presente estudo, serão analisados aspetos cruciais do desenvolvimento e implantação de um plano de marketing internacional no mercado da Indonésia para a indústria metalomecânica. O plano será desenvolvido com base na estrutura sugerida por Cateora, Gilly e Graham, em 2013. Este divide-se em quatro principais capítulos definidos como análise preliminar, definição do mercado e marketing mix, desenvolvimento do plano de marketing e implementação e controlo. A primeira etapa passa...

Environmental impacts caused by the shrimp industry at city of de Nísia Floresta (RN

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Guilherme Dumaresq de Oliveira

2008-09-01

Full Text Available In this work, the aim is to demonstrate the growth of the shrimp breeding (Carcinicultura in Rio Grande do Norte, Brazil, as well as studying the environmental impacts generated by the activity in the mangrove ecosystem. Therefore, the importance of such environment will be showed, considering that the activity depends on that environment to subsist. Thus, environmental impacts are generated by the activity in the mangrove ecosystem. In this article, the deforestation generated in the Environmental Conservation Areas (APA, in Portuguese of mangroves and riparian forest used for constructing tanks for shrimp breeding in Nísia Floresta, Rio Grande do Norte will be analyzed. There is, also, the aim of communicating the existence of the Recovery Plan for the Permanent Preservation Area (PRAPP, in Portuguese, elaborated by Idema (Institute of economic development and environment, the governmental agency responsible for controlling the Environment.

Conversações sobre a "boa morte": o debate bioético acerca da eutanásia Conversations on the "good death": the bioethical debate on euthanasia

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Rodrigo Siqueira-Batista

2005-02-01

Full Text Available A despeito das grandes discussões hodiernas sobre a eutanásia, permanecem ainda muitos pontos em aberto, aparentemente insolúveis, aguardando que um melhor tratamento conceitual seja desenvolvido. Neste âmbito podem ser incluídos os "preconceitos e fundamentalismos" em relação ao tema — a eutanásia ainda é vista como tabu em boa parte da sociedade, especificamente no caso do Brasil —, as imprecisões semânticas do vocábulo e as acérrimas tensões argumentativas em torno do tema — levando-se em consideração os princípios da sacralidade da vida, da qualidade de vida e da autonomia e o argumento da assim chamada "ladeira escorregadia" ou slippery slope. Compor o horizonte de indagação acerca da eutanásia, partindo dos antecedentes históricos em direção a um melhor equacionamento do problema — e delimitação de perspectivas vindouras necessárias à sua melhor compreensão — é, pois, o objetivo do presente ensaio.Despite extensive current debate on euthanasia, many open and apparently unsolvable issues persist, awaiting a better conceptual treatment. The area includes "prejudices and fundamentalisms" in relation to the theme, still viewed as taboo by a major share of society, specifically in the case of Brazil, while semantic imprecision in the term and argumentative tensions surround the issue, focusing on the principles of sacredness of life, quality of life, and autonomy and the so-called "slippery slope" argument. The purpose of the current essay is thus to serve as a sphere of inquiry concerning euthanasia, moving from historical antecedents towards a better solution to the problem and the demarcation of necessary future perspectives for enhanced understanding of the issue.

Identidades religiosas no mundo romano: o caso de judeus e cristãos na Ásia Menor dos séculos I e II d.C.

Directory of Open Access Journals (Sweden)

Monica Selvatici

2016-01-01

Full Text Available No quadro dos estudos sobre a questão das identidades religiosas na antiguidade, o presente artigo tem por objetivo analisar a identidade judaica construída pelos judeus da Ásia Menor no século I d.C. e as implicações que tal construção identitária possui sobre a formação e composição étnica das comunidades cristãs nesta mesma região. O artigo se propõe, em seguida, examinar a construção da identidade cristã em meio às relações conflituosas, sobretudo no século II d.C., que a população grega da Ásia Menor e as autoridades romanas mantêm com os cristãos ali residentes. Para tanto, são analisados os textos neotestamentários Atos dos Apóstolos e Apocalipse, além das obras de Justino o mártir e a correspondência entre Plínio o jovem e o imperador Trajano acerca dos cristãos.

Análise quantitativa do processo de erosão/deposição nas falésias da APA Tambaba e sua ocupação nos limites da APP

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Thaís Regina Benevides Trigueiro Aranha

2013-08-01

Full Text Available O litoral brasileiro é banhado pelo Oceano Atlântico e composto por diversas paisagens ao longo da costa. Entre elas encontram-se as falésias, que, por sua beleza, atraem a exploração turística o que, muitas vezes, compromete seu equilíbrio. Com a finalidade de proteger o meio ambiente das ações antrópicas, o poder público vem criando áreas para preservar e/ou conservar o meio ambiente, entre elas existem as APA e as APP. O objetivo do presente trabalho foi analisar a variabilidade espaço-temporal da linha de ruptura do relevo, na borda das falésias da APA Tambaba, entre os anos de 1985 e 2012; e identificar a existência de edificações dentro da APP no ano de 2012. Para tanto, foram utilizadas imagens do satélite Quickbird de 2012, do satélite IKONOS II de 2005 e fotos aéreas de 1985 para delimitação das linhas das falésias; o DSAS, que é uma extensão gratuita do ArcGIS, para obtenção de taxas de variação da linha de ruptura do relevo; e o software ArcGIS para delimitação e análise das APP. Como resultados, foram identificadas variações no movimento das linhas estudadas, tanto para erosão como para deposição nas falésias da APA Tambaba. No maior trecho da APA obteve-se uma média de -0,17m/ano para erosão e de 0,49m/ano para deposição, já no menor trecho a média de erosão foi -0,38m/ano e de deposição 0,14m/ano. Foi comprovada a existência de edificações irregulares correspondente a 22.818,91 m², o que equivale a aproximadamente 3% da área total da APP.

Ärimees Armin Karult raha nõudnud "rullnokad" toimetasid politsei nina all / Rasmus Kagge, Risto Berendson

Index Scriptorium Estoniae

Kagge, Rasmus, 1977-

2008-01-01

Ilmunud ka: Postimees : na russkom jazõke 17. jaan. 2008, lk. 2-3. Raplamaa noorukeid Ardot ja Viljarit kahtlustatakse kasiinoärimehe Armin Karu tütre Inese pantvangi võtmise kava sepistamises, nad lootsid Olympic Casino keti suuromanikult saada 235 miljonit krooni lunaraha. Politsei tööst kuriteo avastamisel ja nurjamisel. Lisa: Inimröövid. Vt. samas: Armin Karu: kahju, et selliseid tegelasi leidub. Ilmunud ka: samal teemal:Risto Berendsoni art. 18. jaan. Postimees lk. 6; 19. jaan. Postimees ja Postimees : na russkom jazõke lk. 5 ja lk. 3

Agentes ligantes e seus efeitos em concretos refratários alumina-magnésia Binders and their effects on alumina-magnesia refratory castables

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M. A. L. Braulio

2010-12-01

Full Text Available Concretos refratários alumina-magnésia são comumente ligados por cimentos de aluminato de cálcio. Estes materiais apresentam, em temperaturas elevadas, uma reação de caráter expansivo decorrente da espinelização in-situ (MgAl2O4. Quando ligados por cimentos, reações adicionais (formação de CA2 e CA6 contribuem para a expansão. Uma alternativa para controlar a estabilidade volumétrica é a substituição do cimento tipicamente utilizado (~30%-p CaO por outro de menor teor de cálcio (~20%-p CaO ou por alumina hidratável. Tais substituições podem afetar as propriedades dos concretos, como a resistência mecânica a frio, a hidratação da magnésia e as propriedades durante e após a sinterização. Deste modo, o objetivo deste trabalho é avaliar o impacto destes ligantes no processamento de concretos alumina-magnésia. Sendo assim, pretende-se utilizar a fonte de ligante como uma ferramenta para a obtenção de concretos refratários com expansão engenheirada, visando-se aumentar a flexibilidade na seleção de materiais aplicados em panelas de siderurgia.The usual binder of alumina-magnesia castables is the calcium aluminate cement. Due to in-situ spinel (MgAl2O4 formation at high temperatures, these materials present an expansive behavior. When bonded with cement, further reactions (CA2 and CA6 formation also contribute to the overall expansion. Changing the most common cement used (~ 30 wt.% CaO for other containing less calcia (~ 20 wt.% CaO or for hydratable alumina are suitable alternatives for controlling the castables' volumetric stability. Nevertheless, the binder replacement may affect castables properties, such as cold mechanical strength, MgO hydration degree and properties during and after sintering. Therefore, the objective of the present paper is to analyze the effects of these binders on the alumina-magnesia castables processing. As a result, the binder systems can be used as a tool for designing the alumina

Effective e-learning for health professional and medical students: the experience with SIAS-Intelligent Tutoring System.

Science.gov (United States)

Muñoz, Diana C; Ortiz, Alexandra; González, Carolina; López, Diego M; Blobel, Bernd

2010-01-01

Current e-learning systems are still inadequate to support the level of interaction, personalization and engagement demanded by clinicians, care givers, and the patient themselves. For effective e-learning to be delivered in the health context, collaboration between pedagogy and technology is required. Furthermore, e-learning systems should be flexible enough to be adapted to the students' needs, evaluated regularly, easy to use and maintain and provide students' feedback, guidelines and supporting material in different formats. This paper presents the implementation of an Intelligent Tutoring System (SIAS-ITS), and its evaluation compared to a traditional virtual learning platform (Moodle). The evaluation was carried out as a case study, in which the participants were separated in two groups, each group attending a virtual course on the WHO Integrated Management of Childhood Illness (IMCI) strategy supported by one of the two e-learning platforms. The evaluation demonstrated that the participants' knowledge level, pedagogical strategies used, learning efficiency and systems' usability were improved using the Intelligent Tutoring System.

O Paquistão e as estratégias ocidentais para a Ásia Meridional

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Abelardo Arantes Júnior

2003-06-01

Full Text Available Confrontadas com o risco de guerra nuclear entre o Paquistão e a Índia, as potências ocidentais têm procurado exercer algum controle sobre os acontecimentos no Sul da Ásia; instaram os dois países a encetar negociações bilaterais, promoveram a não-proliferação e aplicaram sanções de tempos em tempos. O Paquistão é muito sensível às políticas ocidentais, sobretudo às dos Estados Unidos, porém nunca abriu mão de dois critérios fundamentais de sua política externa: a exigência de autodeterminação para a Cachemira e a dissuasão nuclear. Os Estados Unidos agora mostram um poder e uma influência incontrastáveis, mas após a crise do Iraque a unidade das grandes potências revela fissuras. Ao mesmo tempo, o retorno ao regime civil e parlamentar no Paquistão aumenta a força dos partidos nacionalistas e islâmicos, que querem conter a influência dos Estados Unidos e ampliar os laços com a França, a Alemanha, a Rússia e a China. Nesse novo e fluido ambiente político, a evolução das relações entre o Paquistão e a Índia terá forte impacto sobre as estratégias ocidentais para o Sul da Ásia e para o mundo em geral.Faced with the risk of a nuclear conflict between Pakistan and India, the Western powers have tried to exert a measure of control upon events in South Asia; they urged those two countries to start bilateral negotiations, promoted non-proliferation, and from time to time applied sanctions. Pakistan is very sensitive to Western policies, above all those of the United States, but it never gave up two fundamental criteria of its foreign policy: the demand of self-determination for Kashmir and nuclear deterrence. The United States now shows unmatched power and influence, but after the Iraqi crisis the unity of the great powers became shaky. At the same time the return to a civilian and parliamentarian regime in Pakistan added strength to the nationalist and Islamic parties, which want to contain United States

Disponibilidade de água no solo e crescimento de artemísia

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Carvalho Luciana M. de

2003-01-01

Full Text Available Plantas de artemísia (Tanacetum parthenium L. Schultz-Bip., cultivadas em vasos com substrato mantido na capacidade de campo, a 90%, a 70% e a 50% da capacidade de campo foram comparadas quanto à altura, acúmulo de massa fresca na parte aérea, teor relativo de clorofila e teor de prolina. O teor relativo de clorofila foi estimado por meio do clorofilômetro SPAD-502, enquanto o teor de prolina foi determinado por colorimetria. Verificou-se reduções de 16% na altura e de 22,5% no acúmulo de massa fresca nas plantas crescidas a 50% da capacidade de campo, em relação àquelas crescidas a 90% da capacidade de campo. O teor relativo de clorofila nas folhas, em quaisquer dos níveis hídricos, decresceu com o tempo, indicando tendência à senescência. Apesar da redução contínua nos níveis de clorofila, as plantas mantidas a 50% da capacidade de campo tiveram, durante todo o tempo acompanhado, teor relativo de clorofila cerca de 30% mais alto comparado às plantas mantidas a 90% da capacidade de campo. O teor de prolina também foi maior nessas plantas, indicando ocorrência de estresse por deficiência hídrica e ajuste osmótico. O maior teor relativo de clorofila e de prolina nas folhas expandidas das plantas sob deficiência hídrica pode ser utilizado como indicativo de estresse.

Causas de morte e razões para eutanásia de cães da Mesorregião do Centro Ocidental Rio-Grandense (1965-2004)

OpenAIRE

Fighera, Rafael A.; Souza, Tatiana M.; Silva, Marcia C.; Brum, Juliana S.; Graça, Dominguita L.; Kommers, Glaucia D.; Irigoyen, Luiz F.; Barros, Claudio S.L.

2008-01-01

Este estudo teve como objetivo principal determinar a prevalência das doenças que culminam em morte ou que fazem com que os cães da Mesorregião do Centro Ocidental Rio-Grandense sejam submetidos à eutanásia. Para isso, foram revisados todos os protocolos de necropsia de cães, arquivados no Laboratório de Patologia Veterinária (LPV) da Universidade Federal de Santa Maria (UFSM), realizadas entre janeiro de 1965 e dezembro de 2004. Nos arquivos do LPV-UFSM foram encontrados 4.844 protocolos de ...

Knowledge of the definition of euthanasia: study with doctors and caregivers of Alzheimer's disease patients O conhecimento da definição de eutanásia: estudo com médicos e cuidadores de pacientes com doença de Alzheimer

Directory of Open Access Journals (Sweden)

Luciana Pricoli Vilela

2009-01-01

Full Text Available BACKGROUND: Euthanasia is an increasingly debated subject among specialized professionals and also among lay people, even in countries such as Brazil where it is not authorized. It is questionable, however, if the concept of euthanasia is well known by these persons. OBJECTIVE: The goal of this study was to investigate knowledge about the definition of euthanasia by family caregivers of patients with dementia and by specialized physicians and also to investigate their personal opinion on this topic. METHODS: We prospectively interviewed 30 physicians from three different medical specialties and 40 family caregivers of patients with Alzheimer's disease using a structured questionnaire. Two clinicalvignettes were also presented to the physicians in order to ascertain their personal opinion about euthanasia. RESULTS: Among the caregivers, 10 (25.0% knew the correct definition of euthanasia. Regarding their personal view, nine (22.5% were in favor, while 20 (50.0% were against. The remaining 11 (27.5% caregivers were unable to define their position. Among the physicians, 19 (63.3% gave a coherent answer regarding the definition of euthanasia. When they were presented with the clinical vignettes, less than 50% of them were in favor of euthanasia. CONCLUSION: The definition of euthanasia was unknown by most of the lay individuals and also by one third of the physicians. Although it is not officially approved in Brazil, a small proportion of family caregivers and also of specialized physicians would be in favor of the practice of euthanasia.INTRODUÇÃO: A eutanásia é um tema de crescente debate entre profissionais da área de saúde e também entre o púbico leigo, mesmo em países nos quais não é legalizada, como no Brasil. Entretanto, é questionável se a definição do termo é bem conhecida por essas pessoas. OBJETIVO: O propósito do presente estudo foi investigar o conhecimento sobre a definição de eutanásia entre cuidadores familiares

Näitused / Katrin Kurik

Index Scriptorium Estoniae

Kurik, Katrin

1998-01-01

Linnagalerii Tallinnas: Anna Pauli tekstiilid ja Andras Huberi skulptuurid (Ungari); Kullo lastegalerii: Heli Männi ja Tondiraba keskkooli kunstiklasside õpilaste "Veneetsia maskid"; Tammsaare majamuuseum: Kersti Karu keraamika

DESARROLLO DE UN SISTEMA EN FLUJO MEDIANTE INYECCIÓN SECUENCIAL (SIA) PARA LA DETERMINACIÓN DE ZINC EN LECHE EN POLVO Y FÓRMULAS INFANTILES

OpenAIRE

Mariela Pistón; Moisés Knochen

2011-01-01

Se presenta el desarrollo y optimización de un sistema en flujo con inyección secuencial (SIA) para la determinación de zinc en leche en polvo y fórmulas infantiles. La determinación se basa en la reacción de Zn(II) con zincón a pH 9 en presencia de citrato de sodio para enmascarar interferentes de la matriz con detección espectrofotométrica a 612 nm. El sistema fue optimizado mediante experimentos multivariantes. El sistema validado presentó un rango lineal de 0.4 a 10 mg L-1, la precisión d...

Hansapank is the best Baltic brand / Aigars Rungis

Index Scriptorium Estoniae

Rungis, Aigars

2003-01-01

Eesti, Läti ja Leedu ettevõtete turundustegevusest Baltimaades. Kommenteerivad Robin K. Rindehed, Kristiina Kõiv, Margus Sameli ja Kaarel Karu. Vt. samas intervjuud Põlva Piima turundusjuhi Sven Puussepaga

Ülevaade akordionimängu ja -õpetuse arengust Eestis = The history of accordion performance and pedagogy in Estonia / Tiina Välja

Index Scriptorium Estoniae

Välja, Tiina, 1962-

2014-01-01

Lähemalt akordionistidest Robert Salong, Johann Lõhmus, Leopold Vigla, Artur Aola, Woldemar Koch, Vello Karu, Venda Tammann, Heinrich Annion. Ka akordionialase kõrghariduse omandamisest väljaspool Eestit

SIA "Statoil Fuel & Retail Latvia" komunikācijas sociālajos medijos; klientu uzrunāšana un uzklausīšana

OpenAIRE

Černova, Egita

2013-01-01

Bakalaura darbā "SIA "Statoil Fuel & Retail Latvia" komunikācijas sociālajos medijos; klientu uzrunāšana un uzklausīšana" tika pētīta uzņēmuma komunikācija sociālajos tīklos - komunicēšanas veids, identificējot sociālo tīklu lietotāju viedokli par to. Darba mērķis izpētīt „Statoil” komunikāciju sociālajos medijos un secinājumus piedāvāt kā ierosinājumus uzņēmuma komunikācijas pilnveidošanai. Darba teorētisko daļu veido nodaļas par Gruniga sabiedrisko attiecību komunikācijas modeļiem, so...

Radiation safety in the Moscow region: Experience of cooperation SUE SIA Radon with mass media and public

Energy Technology Data Exchange (ETDEWEB)

Grishin, O.; Rakov, S. [SUE SIA RADON, Moscow (Russian Federation)

2012-07-01

Radiation safety in the present period acquires complex character and closely corresponds with other elements of social and political process, with various spheres of public life. After earthquake in Japan in March 11, 2011 and emergency on the nuclear power plant Fukushima-1 the theme of radiating safety of megapolises has today become urgent, as never. Provision of radiation safety of the Moscow region, taking into account a number of factors, is an important problem in a context of modernization state. Today in sphere of radio ecological safety there are certain achievements: new monitoring systems are developed, technological processes are improved, new information-communicative channels of interaction with mass media and public are formed. Information policy of enterprises the functioning of which is connected with provision of safe ecological conditions and its monitoring is focused on constant and duly informing of public through mass-media. Experience and technologies of interaction with mass-media and public of Moscow State Unitary-Enterprise- united ecological, scientific and research centre of decontamination of radioactive waste and environmental protection (State Unitarian Enterprise, Scientific and Industrial Association Radon, SUE SIA RADON) is submitted in the article. (author)

Radiation safety in the Moscow region: Experience of cooperation SUE SIA Radon with mass media and public

International Nuclear Information System (INIS)

Grishin, O.; Rakov, S.

2012-01-01

Radiation safety in the present period acquires complex character and closely corresponds with other elements of social and political process, with various spheres of public life. After earthquake in Japan in March 11, 2011 and emergency on the nuclear power plant Fukushima-1 the theme of radiating safety of megapolises has today become urgent, as never. Provision of radiation safety of the Moscow region, taking into account a number of factors, is an important problem in a context of modernization state. Today in sphere of radio ecological safety there are certain achievements: new monitoring systems are developed, technological processes are improved, new information-communicative channels of interaction with mass media and public are formed. Information policy of enterprises the functioning of which is connected with provision of safe ecological conditions and its monitoring is focused on constant and duly informing of public through mass-media. Experience and technologies of interaction with mass-media and public of Moscow State Unitary-Enterprise- united ecological, scientific and research centre of decontamination of radioactive waste and environmental protection (State Unitarian Enterprise, Scientific and Industrial Association Radon, SUE SIA RADON) is submitted in the article. (author)

Sem prioritetov Tallinna

Index Scriptorium Estoniae

2003-01-01

Tallinna linnakantselei Eurointegratsioonibüroo juhataja Hedi Pika, projektijuhi Tõnu Karu ja Tallinna alalise esindaja Brüsselis Kaido Sireli tööst Euroopa Liidu struktuurifondide projektide realiseerimisel

Uma "morte suave": valores religiosos e laicos nos discursos sobre ortotanásia A "gentle death", religious and lay values in the discourses about orthothanasia

Directory of Open Access Journals (Sweden)

Rachel Aisengart Menezes

2012-01-01

Full Text Available Este artigo aborda a controvérsia em torno da gestão do término da vida, a partir da análise da ação civil pública provocada pelo Ministério Público Federal, com o intuito de revogar a Resolução 1805/2006 do Conselho Federal de Medicina sobre a ortotanásia. Consideram-se aqui os argumentos médico e jurídico, em suas articulações com valores religiosos. A reflexão acerca dos discursos no processo judicial, em defesa de cada posicionamento (favorável e contrário à autorização legal da ortotanásia possibilita uma compreensão das tramas e dos atores sociais envolvidos nos debates contemporâneos sobre os limites da vida, sobre as possibilidades de intervenção médica e acerca dos direitos de autonomia individual, diante da faculdade de tomada de decisões no último período de vida, no caso de pessoa com doença crônico-degenerativa, em fase terminal.This article addresses the controversy surrounding end-of-life management, based on an analysis of the Public Civil Suit, brought by the Federal Prosecutor's Office, which aimed to revoke the Federal Medical Council's Resolution 1805/2006 about orthothanasia. The reflection about the discourses in the judicial proceedings, in defense of each position (for and against the legal authorization of orthothanasia, makes it possible to understand the threads and social actors involved in contemporary debates about the limits of life, the possibilities for medical intervention and the rights to individual autonomy, in face of the decision making process during the last stage of life, in the case of a person suffering the terminal phase of a chronic degenerative disease.

Ventilação mecânica e obstinação terapêutica ou distanásia, a dialéctica da alta tecnologia em medicina intensiva

Directory of Open Access Journals (Sweden)

Filipe Monteiro

2006-05-01

Full Text Available Resumo: Distanásia ou qualquer um dos seus sinónimos é uma consequência do excesso terapêutico em relação ao prognóstico esperado. A obstinação terapêutica é um dos dilemas éticos mais angustiantes no quotidiano de medicina intensiva, apesar de a sua apreciação encontrar um suporte normativo em várias instituições e organizações. A manutenção ou não suspensão da ventilação mecânica numa determinada circunstância de fim de vida pode ser considerado como um exemplo paradigmático de obstinação terapêutica.A compreensão desta postura passa pela análise e reflexão do acto médico à luz de alguns conceitos ético-filosóficos. Abstract: Dysthanasia or any of its synonyms is a consequence of excessive technical science, without any reasonable chance of achieving a therapeutic benefit for the patient.Medical futility is a distressing ethical dilemma of intensive care medicine. Its recognition has led to a precept support in various institutions and organizations.Not withdrawing or withholding mechanical ventilation in certain circumstances can be considered as a paradigmatic model of medical futility.The understanding of this posture implies a philosophical approach and reflexion of medical practice. Palavras-chave: Ética, obstinação terapêutica, distanásia, medicina intensiva, Key-words: Ethics, medical futility, dysthanasia, intensive medicine

Raamat algajale disainerile

Index Scriptorium Estoniae

2007-01-01

Markko Karu osales Londonis Briti Nõukogu korraldatud rahvusvahelisel noorte disaineritest ettevõtjate võistlusel - projektiks oli käsiraamat äsja ülikooli lõpetanud disaineritele. Konkursi võitis venetsueela disainer Sigal Cohen

Taaskasutuses London / Marlen Promann

Index Scriptorium Estoniae

Promann, Marlen

2007-01-01

"100% Disain London" messist, kus peateemaks oli säästlikkus disainis, materjalides, tehnoloogias ja tootmises. Markko Karu jõudis sellel noore disainiettevõtja auhinna finaali (International Young Design Entrepreneur of the Year)

Evaluation of Water Consumption by Car Wash Facilities in Bauchi ...

African Journals Online (AJOL)

PROF HORSFALL

Nigeria. 2Ofijidalillah Environmental Services, Ado Karu, Nasarawa State Nigeria ... were analysed using statistical method such as random sampling techniques and simple descriptive ... weekend, a long queue of cars is usually formed, all.

Vadītāju vadības lomu novērtējums uzņēmumā SIA "DKD".

OpenAIRE

Tomiņš, Dāvis

2016-01-01

Bakalaura darba tēma ir “Vadītāju vadības lomu novērtējums uzņēmumā SIA DKD”. Bakalaura darba mērķis ir, pamatojoties uz pieejamo informāciju, par vadības lomām un pētījumā iegūto datu analīzi, pilnveidot vadītāja vadīšanas pieejas organizācijā, identificējot nepilnības vadītāju lomu izmantošanā. Darba mērķa sasniegšanai autors izvirzīja sekojošus uzdevumus - iepazīties un izpētīt zinātnisko literatūru par vadītāja vadības lomām, izpētīt uzņēmuma sabiedrība ar ierobežotu atbildību “DKD” vadīb...

Finanšu pārskata revīzija un tās gaita uzņēmumā SIA “X”

OpenAIRE

Pocjus, Evita

2016-01-01

Diplomdarba tēma: „Finanšu pārskata revīzija un tās gaita uzņēmumā SIA „X”” Finanšu pārskata revīzija ir būtiska, jo arī Latvijas Zvērināto revidentu asociācijas apkopotie statistikas dati norāda, ka Latvijā ~90% no pirmreizēji revidētiem uzņēmumiem tiek atklātas būtiskas neatbilstības grāmatvedības uzskaitē, tās atbilstībai LR likumiem un normatīviem aktiem, kā arī finanšu pārskata sagatavošanā. Finanšu pārskata revīzija ir nepieciešama katram uzņēmumam, kurš grib iegūt klientu un sadarbība...

Eutanásia: pelas veredas da morte e da autonomia Euthanasia: along the road of death and autonomy

Directory of Open Access Journals (Sweden)

Rodrigo Siqueira-Batista

2004-01-01

Full Text Available O artigo parte da pergunta: o estabelecimento de um conceito de morte, que possa ser considerado fidedigno e, portanto, consensual, seria premissa crucial para a legitimação moral da eutanásia? Procura responder, expondo os problemas que cercam as tentativas de uma definição - científica - de morte, no momento em que se tenta utilizá-la na tomada de decisões - éticas - em relação ao fim da vida, como no caso da eutanásia e do suicídio assistido. Baseia a argumentação na Lei de Hume, que proíbe a inferência de "valores" a partir de "fatos", e na concepção evolutiva de conceitos científicos, decorrente da distinção, de origem kantiana, entre o que é (coisa em si ou númeno e o que é conhecido (ou fenômeno, e cuja principal conclusão, de tipo metodológico, é a incomensurabilidade entre a ordem dos fatos e dos valores, ou seja, uma definição de um evento/processo como a morte só pode ser comparada com outra definição pertencente à mesma ordem, o mesmo aplicável aos valores. De outro modo, o manuscrito procura delimitar um referencial alternativo para o debate, que, apesar de suas limitações, se mostra bastante útil para a argumentação bioética: o princípio da autonomia, intrínseco à ordem dos valores.This article sets out from the question: Would a definition of the concept of death, which could be considered trustworthy and therefore consensual, be considered crucial for the moral legitimacy of euthanasia? It seeks to address this quest expounding on the problems involving the attempts of a scientific definition of death when this definition is necessary for ethical consideration related to the end of life, as it is the case in euthanasia or assisted suicide. The argumentation is based on Hume's Law which prohibits "values" to interfere with "facts" and on the evolutionary concept of scientific ideas arising from Kant's famous distinction between the unknowable thing-in itself and the knowable thing

Järjekordne kogus kergesti riknevat kaupa / Rait Avestik

Index Scriptorium Estoniae

Avestik, Rait, 1974-

2004-01-01

Teatritudengite diplomilavastustest - H. Ibseni "Nukumaja" K. Sinissaare lavastuses, Eesti Humanitaarinstituudi teatriõppetooli bakalaureusetöö, A. Kivirähki ja J. Karu "Asjade seis" T. Ojasoo lavastuses, EMA Kõrgema Lavakunstikooli 21. lennu bakalaureusetöö

Monitoring SMI kak sredstvo borbõ za rõnok / Triin Raetnik

Index Scriptorium Estoniae

Raetnik, Triin

2007-01-01

Firmad tellivad ajakirjanduse monitooringuid, et jälgida ajakirjanduse hoiakut ettevõtte suhtes - ajakirjandus võib avaldada suurt mõju ettevõttest pildi loomisel. Samuti on monitooringud hea infoallikas konkurentide tegevusega kohta. Kommenteerib Sigrid Karu-Holloway

Apropriações da Instrução ao Sósia na análise da atividade de trabalho

Directory of Open Access Journals (Sweden)

Alda Karoline Lima da Silva

Full Text Available Resumo Este artigo fundamenta-se em quatro experiências de pesquisa nas quais foi utilizada a técnica de Instrução ao Sósia (IaS para análise da atividade de trabalho em variados contextos laborais. São apresentadas e discutidas as aplicações da técnica nessas pesquisas norteadas pela abordagem teórica e metodológica da Clínica da Atividade. As experiências mencionadas efetivaram-se em diferentes ambientes laborais - hospitais, universidades, praias - com seus respectivos participantes (profissionais de saúde, professores e trabalhadores informais. O uso da técnica ensejou diversos fenômenos psíquicos, dentre os quais se destaca a reflexão do trabalhador sobre sua atividade, tanto no âmbito da dimensão clínica da atividade de trabalho como na esfera da identificação de competências diante os possíveis desenrolar da atividade. As contribuições oriundas de tais experiências permitem indicar a técnica para futuros estudos em diferentes contextos laborais, o que evidencia amplas possibilidades de utilização.

Kas maavalitsuste rong on juba ära läinud? / Tõnis Tõnisson

Index Scriptorium Estoniae

Tõnisson, Tõnis, 1945-

2007-01-01

Järg 12. mai lk. 13. Oma arvamust maavalitsuste kaotamise suhtes avaldavad Rapla maavanem Tõnis Blank, omavalitsusliidu esimees Kehtna vallavanem Kalle Toomet, ROLi tegevdirektor Silvi Ojamuru, Kohila vallavanem Hillar Kalmet ja Märjamaa vallavolikogu esimees Villu Karu

"Head käed" pääses Berliini filmifestivalile / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2002-01-01

Peeter Simmi mängufilmi näidatakse järgmisel Berliini filmifestivalil Panorama programmis. Teine eesti mängufilm - Arvo Iho "Karu süda" linastub vaid festivali filmiturul. Ühelgi rahvusvahelisel festivalil film siiani pole osalenud

Vault, Arch and the Pomegranate Tree / Eva Laantee Reintamm

Index Scriptorium Estoniae

Laantee Reintamm, Eva

2007-01-01

Tallinnas Aedvilja ja Karu tänava nurgal asuvast uuest sünagoogist, projekteerija KOKO Arhitektid. 1883. aastal avati Maakri tänaval Nikolai Thamme projekteeritud Eesti esimene sünagoog (hävitati 1944). Juudi kogukonna ajaloost

Aasta ema tekki kootud armastus / Grethe Rõõm

Index Scriptorium Estoniae

Rõõm, Grethe

2009-01-01

44 eesti naist kudusid oma head soovid tekilappidesse, mis talgutööna heegeldati kokku aasta emale emadepäeval kingitavaks tekiks. Oma muljeid jagavad Helmi Valdna, Leili Karu, Marju Avald, Eddy Tulko, Maile Veelaid ja Veronika Pinka

Amnésia Global Transitória: Relato de Caso/ Transitory Global Amnesia: a Case Report

Directory of Open Access Journals (Sweden)

Olimpio Antônio Cornehl da Silva

2014-03-01

Full Text Available Introdução: A amnésia global transitória (AGT consiste na ocorrência de sintomas como perda da memória e perda da orientação temporal e/ou espacial, de caráter temporário, e cuja causa não está associada às condições neurológicas mais comuns e clássicas, como epilepsia ou acidente vascular cerebral (AVC. Os maiores fatores de risco conhecidos para a AGT são a idade, geralmente ocorrendo em maiores de 50 anos, a ocorrência de episódios de estresse ou esforço físico antes do evento, sendo comum ocorrer em pessoas com antecedentes de enxaqueca. Casuística: Neste trabalho foi relatado o caso de um paciente de 61 anos, do sexo masculino, com história de amnésia com duração de um período de 5 horas. O mesmo foi submetido ao exame de ressonância magnética no dia seguinte que não evidenciou alterações; devido à suspeita de AGT, um novo exame de RM foi realizado três dias depois, demonstrando pequena área de alteração de sinal no hipocampo direito. Discussão: Os testes diagnósticos a serem realizados incluem exames para investigar um possível AVC ou episódio epiléptico. Além disso, é importante a investigação de fatores psicossomáticos e pesquisa de transtornos psiquiátricos associados, bastante relacionados à ocorrência de AGT. Conclusão: Atualmente, ainda há estudos sobre esta patologia, principalmente em relação a sua causa subjacente, levantando-se a hipótese de que seja um sintoma comum a diversas doenças e não uma patologia em si, tornando de suma importância os exames complementares de imagem no seu diagnóstico. Introduction: Transient global amnesia (TGA is the occurrence of symptoms such as loss of memory and orientation to time and/or space, with a temporary character, and whose cause is not linked to the most common classic and neurological conditions, such as epilepsy or stroke. The major known risk factors for TGA are age, usually occurring in greater than 50 year-old people the

MIFF 2002 / Marianne Kõrver

Index Scriptorium Estoniae

Kõrver, Marianne, 1980-

2002-01-01

Moskva 24. rahvusvahelise filmifestivali filme. Nikolai Baturini romaani "Karu süda" põhjal vändatud Arvo Iho filmi näitamisele järgnenud pressikonverentsist. Ka FIPRESCI auhinna saanud Aleksandr Rogozhkini filmist "Kägu". Lisatud laureaatide nimekiri

SIA

International Nuclear Information System (INIS)

Carniel, B.; Stefanini, A.; DeGrandi, G.

1987-01-01

In this paper the authors describe the design of a knowledge-based supporting system for Non Destructive Analysis of Plutonium isotopic composition, which fits into an integrated data evaluation scheme for safeguards. This system is intended to be an intelligent assistant to the inspection procedure, able to generate as much as possible correct measurements, to guide the inspector throughout the procedure and to report descriptive data to the data evaluation system. The problem of improving the measurement quality is tackled using expert system approach, which should convey into this tool some of the physicist knowledge. The system has been designed at CISE laboratories, in the frame of the cooperation among the JRC of Ispra, the International Atomic Energy Agency (IAEA) and the Safegards Directorate (DCS) of Luxemborg for the fissile material control and management program

Kultuuriakadeemias lavastub ökomuusikal / Margus Haav

Index Scriptorium Estoniae

Haav, Margus

2006-01-01

Viljandi kultuuriakadeemia mustas saalis etendub second-hand-muusikal "Pinipulst, kassiraisk ja latsõtükk", mis on Kadri Karu butafoori-dekoraatori eriala lõputöö. Lavastus toetub täies mahus second-hand-filosoofiale ning teostuslikust seisukohast propageerib ökobutafooriat

Hotell Hilton Tallinn Park / Kersti Pikk

Index Scriptorium Estoniae

Pikk, Kersti

2016-01-01

Äriklassihotellide ketti Hilton kuuluv hotell Tallinnas. Arhitektuurse lahenduse autor Meelis Press. Interjööri kujundasid Soome büroo dSign Vertti Kivi & Co ja Allianss Arhitektid. Hotelli tube ja üldalasid kaunistavad Katrin Karu ja Maria Simsoni maalid

Avatseremoonia = Grand Opening Ceremony : [fotod

Index Scriptorium Estoniae

2011-01-01

Tallinnas Karu tänaval avati 16. mail 2007 uus juudi sünagoog, avamistseremoonial viibisid ka presidendid Toomas Hendrik Ilves ja Arnold Rüütel. Vt. ka foto lk. 36: Boris Oks is reciving medal from the President Mr. Ilves

Tallinna loomaaed näitas eile pegasust / Aivi Lindsalu

Index Scriptorium Estoniae

Lindsalu, Aivi

2004-01-01

IV Läänemeremaade animalistliku skulptuuri festivali võitjad. Osavõtjate ja nende tööde loetelu. Võidutöö oli Vitali Novikovi karu, II koha sai Aleksander Litvinov kotkaga ning kolmandat kohta jagasid Margarita Kamardina kameeleoniga ja Rafael Danieljants jaaguariga

HÖFF / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2008-01-01

Haapsalu õudusfilmide festivalil HÕFF linastuvaid filme - "Ajaroimad" ("Los Cronocrimenes"; režii Nacho Vigalondo), "Mudapoiss" ("El nino de barro"; Jorge Algora), "Orbudekodu" (El orfanato"; Juan Antonio Bayona)

Idioot hingedepuudutaja / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2011-01-01

12. oktoobril esilinastus Fjodor Dostojevski romaanil põhinev Rainer Sarneti mängufilm "Idioot". Film valiti ka 6. oktoobril alanud Lõuna-Korea Busani rahvusvahelise filmifestivali programmi Flash Forward

PÖFF / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2010-01-01

14. Pimedate Ööde filmifestivali filmidest: "Tapja minu sees" (USA-Inglise 2010), "Saladus nende silmades" (Argentina-Hispaania 2009), "Ettearvamatud" (Itaalia 2010), "Polli päevikud" (Saksa-Austria-Eesti 2010), "Undiin" (Iiri-USA 2010), "Kong 211" (Prantsuse 2009)

Betoon ajaloos / Mihkel Karu

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2005-01-01

Eramu ja elamuehituses võeti betoonkonstruktsioonid kasutusele 20. sajandi algul. Auguste Perret' korterelamutest, Tony Garnier' Cite Industrielle plaanist, Le Corbusier' villa Savoye'st, Frank Lloyd Wright'i Kaufmannide villast Pennsylvanias. 10 ill

Horror Haapsalus / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2010-01-01

23.-25. aprillini Haapsalus toimuva 5. Haapsalu Õudus- ja Fantaasiafilmide festivali (HÕFF) filmidest: režissööride Yannick Dahan'i ja Benjamin Rocher "Hord", Srdjan Spasojevic'i "Serbia film", Cory McAbee "Stingray Sam", režissöör Tom Six' "Inimsajajalgne", Shinya Tsukamoto "Tetsuo"

A eutanásia e os paradoxos da autonomia Euthanasia and the paradoxes of autonomy

Directory of Open Access Journals (Sweden)

Rodrigo Siqueira-Batista

2008-02-01

Full Text Available O princípio de respeito à autonomia tem se mostrado muito útil para a argumentação bioética em favor da eutanásia. Sem embargo, a despeito de sua inquestionável eficácia teórica, inúmeras aporias podem ser levantadas, no momento em que se procede a uma análise rigorosa deste conceito, sendo possível colocá-lo em xeque. Com base nesta ponderação, o presente artigo busca investigar o princípio de autonomia, partindo de suas origens nas tradições grega e cristã e mapeando alguns desdobramentos na tradição ocidental, até sua formulação na modernidade, legado de Immanuel Kant. A seguir, são apresentados seus principais paradoxos, no âmbito da filosofia, biologia, psicanálise e política, expondo-se, assim, várias das dificuldades teóricas que precisam ser enfrentadas, a fim de tornar possível sua aplicabilidade no âmbito das decisões relativas ao fim da vida.The principle of respect for autonomy has proved very useful for bioethical arguments in favor of euthanasia. However unquestionable its theoretical efficacy, countless aporiae can be raised when conducting a detailed analysis of this concept, probably checkmating it. Based on such considerations, this paper investigates the principle of autonomy, starting with its origins in Greek and Christian traditions, and then charting some of its developments in Western cultures through to its modern formulation, a legacy of Immanuel Kant. The main paradoxes of this concept are then presented in the fields of philosophy, biology, psychoanalysis and politics, expounding several of the theoretical difficulties to be faced in order to make its applicability possible within the scope of decisions relating to the termination of life.

Author Details

African Journals Online (AJOL)

Bello, M. Vol 41, No 1 (2010) - Articles Socio-economic Factors Influencing the Adoption of Striga Hermonthica Tolerant Maize Varieties Among Farmers in Panda Development Area of Karu Local Government Area, Nasarawa State Abstract. ISSN: 0300-368X. AJOL African Journals Online. HOW TO USE AJOL.

Eesti kasiinofirma sattus Leedus skandaali keskele / Toomas Sildam, Rasmus Kagge

Index Scriptorium Estoniae

Sildam, Toomas, 1961-

2006-01-01

Leedu julgeolekuamet konfiskeeris ajalehe Laisvas Laikrastise kogu 8.septembri tiraazhi, väidetavalt kirjutati ajalehes julgeolekuameti poolt pealtkuulatud telefonikõnedest, millest ühes olevat Eesti suurärimees, Olympic Casino omanik Armin Karu nõudnud oma Vilniuse esindajatelt kokkusaamist temalt raha saanud Leedu sotsiaaldemokraatliku partei liidri Arturas Paulauskasega

Lammasinimene, liblikmees ja karunaine : maagilisest realismist eesti kirjanduse näitel / Andrus Org

Index Scriptorium Estoniae

Org, Andrus

2007-01-01

Maagilisest realismist kolme eesti romaani põhjal: Karl Rumori "Krutsifiks" (Tallinn : Eesti Raamat, 1989), Mehis Heinsaare "Härra Pauli kroonikad" (Tallinn : Perioodika, 2001), Nikolai Baturini triloogia "Karu süda" (Tallinn : Eesti Raamat, 1989), "Kartlik Nikas, lõvilakkade kammija" (Tallinn : Eesti Raamat, 1993), "Kentaur" (Tallinn : Eesti Raamat, 2003)

Simmul sai Anapas auhinna / Ilona Martson, Andres Laasik

Index Scriptorium Estoniae

Martson, Ilona, 1970-

2002-01-01

SRÜ ja Baltimaade 11. filmifestivalil Anapas sai parima meesnäitleja preemia Rain Simmul Nika osa eest Arvo Iho mängufilmis "Karu süda". Videoprogrammi grand prix sai Mikk Ranna animafilm "Sääsk ja hobune", samas märgiti ära ka Mark Soosaare "La Paloma"

V mire skazotshnom, pravdivom / Ella Agranovskaja

Index Scriptorium Estoniae

Agranovskaja, Ella, 1950-

2001-01-01

Mängufilm "Karu süda" : stsenarist ja režissöör Arvo Iho : kaasstsenarist oma romaani põhjal Nikolai Baturin : kaasstsenarist Rustam Ibragimbekov : produtsent Mati Sepping : operaator Rein Kotov : muusika Peeter Vähi : Faama Film ja Cumulus Projekt koos Vene, Saksa ja Tšehhi stuudiodega, 2001

Enteroparasitoses em escolares do Distrito de Martinésia, Uberlândia, MG: um estudo piloto

Directory of Open Access Journals (Sweden)

Carla Borges Ferreira

1997-10-01

Full Text Available Este trabalho avalia a ocorrência de parasitas intestinais em estudantes do Distrito de Martinésia, município de Uberlândia (MG. Foram examinadas 103 crianças, no período de setembro a novembro de 1995, segundo o método de Lutz ou Hoffman, Pons & Janer. O coeficiente geral de prevalência foi de 22,3% e os índices de infecção mais elevados foram observados no grupo etário 8 a 9 anos (34,8%, nos moradores da vila (30,0% e no sexo feminino (26,9%. Helmintoses e protozooses apresentaram taxas de prevalência similares (10,7% e 12,6%, respectivamente. Giardia lamblia foi o único protozoário parasito verificado e apenas um caso de poliparasitismo foi encontrado. Conclui-se que a prevalência de enteroparasitoses no grupo estudado é menor do que o esperado para uma comunidade rural, o que é, provavelmente, uma conseqüência das boas condições sanitárias presentes naquele distrito.This work evaluates the occurence of intestinal parasites in the students of the Martinesia district, Uberlândia municipality, Minas Gerais State. A total of 103 children were examined, from september to november 1995, according to Lutz or Hoffman, Pons and Janer method. The overall prevalence rate was 22.3% and the highest indices of infection were observed in 8-9 age group (34.8%, in village dwellers (30.0% and in females (26.9%. Helminthosis and protozoosis showed similar prevalence rates (10.7% and 12.6%, respectively. Giardia lamblia was the unique protozoan parasite verified and only one case of poliparasitism was found. We concluded that: the prevalence of enteroparasitosis in the studied group is lower than expectations for a rural community, what is, probably, a consequence of the good sanitary conditions presenting in that district.

Vares ja kana : [valmid] / Ivan Krõlov ; tlk. Eduard Kansa, Mart Raud, Timotheos Kuusik, Johannes Semper, G. Õis, Arnold Tulik, Oskar Urgart, Jaan Kärner, Jakob Tamm, Erni Hiir

Index Scriptorium Estoniae

Krõlov, Ivan, 1768(1769)-1844

2006-01-01

Sisu: Vares ja Kana ; Moosekandid ; Vares ja Rebane ; Konn ja Härg ; Pirtsakas Näitsik ; Oraakel ; Rukkilill ; Tuli ja Metsatukk ; Hunt ja Talleke ; Pärdik ja Prillid ; Ahvid ; Tihane ; Eesel ; Kotkas ja Kanad ; Võimumees ja Mõttetark ; Koerte sõprus ; Kasujaotus ; Vaat ; Kvartett ; Teekäijad ja Koerad ; Hunt penilas ; Oja ; Rebane ja Mäger ; Rohutirts ja Sipelgas ; Luiskaja ; Kukk ja Pärlitera ; Jänes jahil ; Hunt ja Kägu ; Haug ja Kass ; Peremees ja Sulane ; Voor ; Elevant maavalitsejaks ; Eesel ja Ööbik ; Külamehe kimbatus ; Elevant ja Mops ; Hunt ja tema Kutsikas ; Kass ja Kokk ; Lõvi ja Sääsk ; Aednik ja Filosoof ; Haned ; Siga ; Vanamees ja kolm noorukit ; Kotkas ja Ämblik ; Lehed ja Juured ; Hunt ja Rebane ; Lohe ; Rästas ; Mehhaanik ; Trishka satter ; Tiik ja Jõgi ; Luik, Haug ja Vähk ; Erak ja Karu ; Mesilane ja Kärbsed ; Lõvi jahisaak ; Talupojad ja Jõgi ; Lilled ; Uudishimulik ; Kaastundlik Rebane ; Kogukonna koosolek ; Demjani kalasupp ; Tihane ja Tuvi ; Hiir ja Rott ; Peegel ja Ahv ; Sääsk ja Karjane ; Talupoeg ja Surm ; Hunt ja Karjased ; Lõvi ja Rebane ; Kamm ; Hunt ja Kurg ; Pilv ; Poiss ja Siug ; Maamees ja Siug ; Kägu ja Tuvike ; Kaks Vaati ; Töökas Karu ; Rebane ja Viinamarjad ; Karu võrgus ; Kirjamees ja Röövel ; Mölder ; Siga Tamme all ; Kärbes ja Mesilane ; Ämblik ja Mesilane ; Rebane ja Eesel ; Siug ja Talleke ; Ööbikud ; Peremes ja Lammas ; Kaks Külameest ; Kaks Koera ; Kass ja Ööbik ; Kalade tants ; Haug ; Habemenoad ; Hiired ; Hunt ja Kass ; Karjane ; Orav ; Damaskuse mõõk ; Koer ja Hobune ; Rebane ; Hundid ja Lambad ; Kägu ja Kukk

Pistise andmine mainet eriti ei kahjusta / Aleksei Günter

Index Scriptorium Estoniae

Günter, Aleksei, 1979-

2005-01-01

Sotsiaalministeeriumi IT-juhile Henry Timmermanile pistist ja altkäemaksu andnud seitse IT-ärimeest pääsesid kriminaalmenetlusest, kuna nad tunnistasid oma seadusvastaseid tegusid ning aitasid kaasa tehingute detailide päevavalgele toomisele. Lisad: Erik Tambaur; Tarvi Tara; Sten Soosaar; Janek Karu; Toomas Perillus; Karel Kannel; Andreas Simsel

Parimad näidendid 2003 Unduskilt ja Lennukilt / Neeme Korv

Index Scriptorium Estoniae

Korv, Neeme, 1974-

2003-01-01

I preemia: Urmas Lennuk "Boob teab", Jaan Undusk "Quevedo"; II preemia: Anu Allas "Lendav rõdu ehk Nagu nad tahtsid", Raivo Kütt "Papa (Sõtse ja venna)"; III preemia Jakob Karu "Asjade seis", Hans Nordberg "aaron : juuni"; ergutuspreemia: Urmas Lennuk "Kadunud kindapood", Urmas Vadi "Kadunud kosmoses", Jaan Võõramaa "Mamma";

Mahukate maksuskeemide uurimine jõuab lõpule / Silva Männik, Inno Tähismaa, Heidit Kaio

Index Scriptorium Estoniae

Männik, Silva, 1974-

2003-01-01

Ilmunud ka: Delovõje Vedomosti 13. august lk.6. Maksuameti peadirektori Aivar Sõerdi tagandamise võis põhjustada tuntud ärimeeste hirm offshore-tehingute avalikustamise ees. Nimekiri: Diveciga seotud seni teada olevad ärimehed; nn. Karu kontori kliente. Kommentaar Silva Männikult: Sõerd - offshore'e kasutava sõpruskonna ühine mure

Majandus laastab kasiinoärimeeste pöörast varandust / Mikk Salu

Index Scriptorium Estoniae

Salu, Mikk, 1975-

2008-01-01

Kasiinoärimees Armin Karu varandus on majanduse jahtumise tõttu vähenenud viie miljardi krooni võrra. Ameerika Ühendriikides on majanduskasv aeglustunud, Las Vegases on langenud mängimisest saadav tulu. Olukorrast Eesti kasiinoäris. Lisa: Kasiinoäri ja majanduse seosed. Diagramm: Eesti kasiinoturg 2007

SIA model for buildings: energy-efficiency path for commercial and residential buildings. Preliminary study on the Swiss model for buildings - Basics for the revision of the 'SIA energy-efficiency path' - Final report; Gebaeudeparkmodell 'SIA Effizienzpfad Energie', Dienstleistungs- und Wohngebaeude. Vorstudie zum Gebaeudeparkmodell Schweiz - Grundlagen zur Ueberarbeitung des SIA Effizienzpfades Energie - Schlussbericht

Energy Technology Data Exchange (ETDEWEB)

Heeren, N.; Gabathuler, M.; Wallbaum, H. [Institut fuer Bauplanung und Baubetrieb, Eidgenoessische Technische Hochschule Zuerich (ETHZ), Zuerich (Switzerland); Jakob, M.; Martius, M.; Gross, N. [TEP Energy GmbH, Technology Economics Policy - Research and Advice, Zuerich (Switzerland)

2009-10-15

The aim of the project was to provide a basis for the revision of the so-called 'Efficiency Path' of the Swiss Association of Engineers and Architects (SIA) in the context of the goals of the 2000-Watt-Society. Particularly, the objective is to find the conditions in which the specific goals of the 2000-Watt-Society for residential, school and office buildings could be reached. Considered indicators are the per capita primary energy use in terms of average power and the greenhouse gas emissions. A bottom-up model was developed to estimate final and primary energy demand of the mentioned building types, broken down by different types of energy utilisation. Assumptions were made regarding the most important physical drivers as well as for regarding energy efficiency parameters of new buildings, building retrofits, building technologies and other energy applications in the residential, school and office buildings. Two basic scenarios were developed: an ambitious efficiency scenario was compared to a reference scenario which included current and foreseeable energy policy elements. Regarding electricity supply three scenario-variants of the so-called Swiss Energy Perspectives of the Swiss Federal Office of Energy (SFOE) were used: variant I b 'business-as-usual - nuclear and central fossil plants', IV a: Path to the 2000-Watt-Society - nuclear' and, IV e 'Path to the 2000-Watt-Society - renewable energies'. With this respect it was found that in the case of the efficiency scenario the influence of the electricity generation mix is relatively small. This finding is explained by the fact that hydro power (which is held more or less at the current level) has a large share in the power supply mix in the case of the efficiency scenario with moderate electricity demand and that hydro power is efficient in terms of primary energy and has considerably low greenhouse gas emissions. The results of the study show that with the underlying

Atrésia Esofágica: Um Desafio desde o Diagnóstico Pré-natal ao Tratamento Cirúrgico

Directory of Open Access Journals (Sweden)

Vera Trocado

2018-02-01

Full Text Available A atrésia esofágica é a anomalia congénita mais comum do desenvolvimento do esófago, caracterizando-se por uma disrupção da sua continuidade, com uma prevalência de cerca de 1 em cada 2500 a 4500 nados vivos. A abordagem desta condição, desde o seu diagnóstico no período pré-natal até ao tratamento cirúrgico no período neonatal, constitui um importante desafio, tanto para o obstetra como para o cirurgião pediátrico. No âmbito do diagnóstico pré-natal, a ecografia, a ressonância magnética, bem como a análise bioquímica do líquido amniótico poderão ser úteis. Por outro lado, no que diz respeito ao tratamento cirúrgico desta condição, dispomos hoje de técnicas cirúrgicas minimamente invasivas, associadas a menor número de sequelas musculoesqueléticas, menor dor no pós-operatório e a um melhor resultado estético final. Neste artigo, os autores fazem uma revisão do papel das diferentes técnicas de diagnóstico pré-natal disponíveis, bem como das diferentes abordagens para o tratamento cirúrgico.

Prevalence of geohelminth in soil and primary school children in ...

African Journals Online (AJOL)

A study of geohelminthes infections among primary school children aged 8 to 13 years was conducted in four selected primary schools in Panda Development Area, Karu LGA, Nasarawa State, Nigeria. Out of four hundred and eighty (480) soil samples collected from the four schools, 314 (82.63) were found to be positive ...

Millest nad kirjutavad ehk Näidendivõistluse tänavusügisene saak / Triin Sinissaar

Index Scriptorium Estoniae

Sinissaar, Triin

2003-01-01

I preemia: Urmas Lennuk, "Boob teab"ja Jaan Undusk, "Quevedo"; II preemia: Anu Allas, "Lendav rõdu ehk Nagu nad tahtsid" ja Raivo Kütt, "Papa" ("Sõtse ja venna"); III preemia Jakob Karu, "Asjade seis" ja Hans Nordberg, "aaron : juuni"; ergutuspreemia: Urmas Lennuk, "Kadunud kindapood", Urmas Vadi, "Kadunud kosmoses" ja Jaan Võõramaa, "Mamma"

Eneseotsingud Nikolai Baturini taigaromaanides / Monica-Linde Klemet

Index Scriptorium Estoniae

Klemet, Monica-Linde

2009-01-01

Nikolai Baturini kolme esimest romaani "Kuningaonni kuningas" (1973), "Leiud kajast" (1977) ja "Karu süda" (1989) ühendab sama keskkond: Siberi põlislaan, taiga. Autori bakalaureusetööl põhinev artikkel vaatleb kolmes romaanis ilmnevaid motiive ning jõuab järeldusele, et kõikide romaanide ühiseks teemaks on kangelase eneseotsingud

Selgusid näidendivõistluse võitjad

Index Scriptorium Estoniae

2003-01-01

I preemia: Urmas Lennuk "Boob teab"ja Jaan Undusk "Quevedo"; II preemia: Anu Allas "Lendav rõdu ehk Nagu nad tahtsid" ja Raivo Kütt "Papa (Sõtse ja venna)"; III preemia Jakob Karu "Asjade seis" ja Hans Nordberg "aaron : juuni"; ergutuspreemia: Urmas Lennuk "Kadunud kindapood", Urmas Vadi "Kadunud kosmoses" ja Jaan Võõramaa "Mamma"

Eesti filmitegijad osalesid Põhjamaade filmifestivalil / Maris Lillak

Index Scriptorium Estoniae

Lillak, Maris, 1970-

2003-01-01

Newcastle-Upon-Tyne'is lõppes ligi 2 nädalat kestnud Põhjamaade filmifestival Nordic Lights, kus kesksel kohal näidati Tyne'i ja Tallinna vahelise lühifilmivõistluse tulemusi. Põhiprogrammis olid ka Arvo Iho "Karu süda" ja Ilkka Järvi-Laturi "Tallinn pimeduses". Oli ka ülevaatlik programm Eesti animatsioonist

José Bernardo : kas nahakunst on olemas? / Maarja Undusk

Index Scriptorium Estoniae

Undusk, Maarja

1998-01-01

Augustis Eestis viibinud mehhiko nahakunstnikust José Maria Bernardo Sappiast, tema loomingust. Nahakunstist maailmas. Eesti nahakunstnike rahvusvahelisse naha-ellu lülitumise võimalustest. Nahaeriala entusiastidest maailmas: portugaallasest Franklin Pereirast, kes alustas ajakirja "The Leather Times" väljaandmist ja Hamburgis tegutsevast Rene Berendsist, Karu galerii omanikust, kes andis välja kataloogi "Leder Gilde"

Format zhurnalnogo lista

Index Scriptorium Estoniae

2003-01-01

Vene Kunstnike Ühenduse korraldatud näitusest Vene Draamateatri galeriis: osaleb 24 kunstnikku 2-3 tööga omal valikul. Ühenduse tuumikuna mainitakse kunstnikke Valeri Laur, Slava Semerikov, Anatoli Strahhov, Vladimir Baciu, Vera ja Vladislav Stanishevskid, uustulnukana - eesti keraamikut Kersti Karu. Sveta Aleksejeva on illustreerinud ühe viiest 2002.aasta kaunimast lasteraamatust

Kepiga korda loomas / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2010-01-01

Režissöör Susanna White'i koguperefilmist "Nanny McPhee ja suur pauk" (USA-Prantsuse-Suurbritannia, 2009). Film tugineb Christiana Brandi raamatutel "Nurse Matilda". Stsenaariumi kirjutas ja peaosa kehastab Emma Thompson

Medellin ja Tallinn / Jakob Karu

Index Scriptorium Estoniae

Karu, Jakob, pseud., 1966-

2008-01-01

Itaalia arhitektuuri- ja disainiajakirjas "Abitare" tutvustati Kolumbia narkopealinnas Medellinis tehtud uuendusi. Sotsiaalse keskkonna analüüsist. Tallinna linnaplaneerimine kui ärihuvide kaardistamine

Kamuflaažmaja / Mihkel Karu

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2013-01-01

Oskuslikult mändide vahele sobitatud eramu Tallinna lähedal. Arhitektid Illimar Truverk ja Priit Hamer (Arhitekt11/Agabus, Endjärv & Truverj Arhitektid). Sisearhitektid Külli Salum ja Riina Harik (Saha In). Veel lõplikult teostamata maastikuarhitektuurse lahenduse kavandasid Kätlin Ölluk ja Kadi Markna. Ehitusaeg: 2010-2012. Elamispind: 409/160 m²

Alguses oli Piaf / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2010-01-01

Režissöör Christopher Nolani põnevusfilmis "Algus" (USA-Inglise 2010) teeb kaasa ka prantsuse näitleja Marion Cotillard. Tuntuks sai näitlejanna peaosaga režissöör Olivier Dahani filmis "Edith Piaf - elusse armunud"

Arhitektuuriuudiseid laiast maailmast / Mihkel Karu

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2006-01-01

Kaitserajatist või tööstushoonet meenutav eramu Coliumo poolsaarel Tšiilis (Pezo von Elrichshausen Architects, valminud 2005). Mooduleramu Tšehhis Beroun'is (Hajek, Hradecny & Speka, valminud 2002-2004). Korterelamud Sloveenias Ljubljanas (BEVK Perovic Arhitekti, valminud 2003-2005). Siseaeda avanevate akendega juuksurisalong/elamu Jaapanis Hokkaido saarel Yachimatas (arhitekt Ken Niizeki/Niizeki Studio, valminud 2002). Korterelamud Šveitsis Zürichis (Pool Architekten, Zürich, valminud 2005). Klaasist eramu Hollandis Oranjewoudis (Borren Staalenhoef Architecten, valminud 2005)

Välismaa arhitektuuriuudised / Mihkel Karu

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2007-01-01

Arhitektuuribüroode Office dA ja Johnston Markelee öko-bensiinijaam. Neutlelings-Riedijk AB projekteeritud elamu Rotterdami tööstuspiirkonnas. Paviljon-kohvik Lissabonis, arhitektid Joao Pedro Falcao de Campos ja Jose Ricardo Vaz. Eramu Prantsusmaal, arhitektuuribüroo Peripherique Architects

Välismaa arhitektuuriuudised / Mihkel Karu

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2008-01-01

Kunstimuuseum New Yorgis. Mälestusmärk Madridi 2004. aasta pommiplahvatuses hukkunutele (FAM Arquitectos). Teaduskeskus Taanis Nordborgis (arhitekt Jürgen Mayer). Eramu Jaapanis (Datar Architects). Noortekeskus Melbourne'is (Phooey Architects). Koolimaja Šveitsis (IPAS)

Telenovela'de keel / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2007-01-01

Kolumbia telenovela "Luna" peategelasi kehastavad venetsueelalane Gaby Espino ja peruulane Christian Meier. Üheks raskuseks töö juures on erinevate aktsentide ühtlustamise vajadus. Lühidalt ka näitlejate varasemast karjäärist

В Таллинне открылась новая синагога / Ксения Репсон

Index Scriptorium Estoniae

Репсон, Ксения

2007-01-01

Tallinnas Karu tänaval avati 16. mail 2007 uus juudi sünagoog, avamistseremoonial viibisid Iisraeli asepeaminister Shimon Peres, Eesti president Toomas Hendrik Ilves, peaminister Andrus Ansip, Venemaa pearabi Berl Lazar, Iisraeli pearabi Yona Metzger ja sünagoogi suurrahastaja Aleksander Bronštein. President Toomas Hendrik Ilves viitas oma kõnes paralleelidele eestlaste ja juutide ajaloos

The new synagogue has given the Jewish community something to sing and dance about / Rein Sikk

Index Scriptorium Estoniae

Sikk, Rein, 1961-

2007-01-01

Tallinnas Karu tänaval avati 16. mail 2007 uus juudi sünagoog, avamistseremoonial viibisid Iisraeli asepeaminister Shimon Peres, Eesti president Toomas Hendrik Ilves, peaminister Andrus Ansip, Venemaa pearabi Berl Lazar, Iisraeli pearabi Yona Metzger ja sünagoogi suurrahastaja Aleksander Bronštein. President Toomas Hendrik Ilves viitas oma kõnes paralleelidele eestlaste ja juutide ajaloos

Vanade pangahoonete kohandamine keskpanga tööks / Märt Karmo

Index Scriptorium Estoniae

Karmo, Märt

2004-01-01

Panga peahoonest (Estonia pst. 13), endisest Vene Riigipanga hoonest (Estonia pst. 13) ja teenistujate elamust (Sakala 6), endisest Aadlipanga hoonest (Estonia pst. 11), endisest maakrediidiseltsi elamust-büroohoonest (Sakala 4), õppe- ja juhtimiskeskusest Kuressaares. Uue pangamaja projektidest (Jüri Karu, Eesti Tööstusprojekt, 1992; AB Rein Murula), sularahaveo turvahoonest (EKE Ehitus ja Hans Tombach, 1993)

Hain Karu : Tallinn ehitab jälle tõusvas tempos / Hain Karu ; interv. Tõnu Vare

Index Scriptorium Estoniae

Karu, Hain

2003-01-01

Tallinna Säästva Arengu ja Planeerimise Ameti asejuhataja sõnul on tänases situatsioonis Tallinnas elamufondi defitsiit: leibkondade arv on suurem kui eluasemete arv, seda näitab ka tüüpkorterite kiire hinnatõus

Transport, dissociation and rotation of small self-interstitial atom clusters in tungsten

International Nuclear Information System (INIS)

Zhou, W.H.; Zhang, C.G.; Li, Y.G.; Zeng, Z.

2014-01-01

Numerical calculations have been performed to study the thermal motion of self-interstitial atom (SIA) clusters in tungsten (W). Molecular dynamics simulations show that SIA clusters exhibit a fast one-dimensional (1D) motion along the close packed 〈1 1 1〉 direction accompanied by a significant mass transport in this direction. A low frequency vibration mode is identified and considered to assist the motion of SIAs. The migration energy of SIA clusters are weakly dependent on their size in the average value of 0.019 eV, which is due to the strong interaction between SIAs revealed by calculating the potential energy curve of artificially moving the SIAs along 〈1 1 1〉 direction as well as nudged elastic band (NEB) method. The rotation process of SIA cluster is studied by activation–relaxation technique and the results show that SIA cluster presents complex rotation process. Our results on the motion SIA cluster may provide updated understanding on the performance decay of materials related to SIA defects

Potencial de uso e qualidade estrutural de dois solos cultivados com cana-de-açúcar em Goianésia (GO Use potential and structural quality of two soils under sugarcane production in Goianésia, Goiás State, Brazil

Directory of Open Access Journals (Sweden)

Eduardo da Costa Severiano

2009-02-01

Full Text Available Com a expansão do setor sucroalcooleiro, tanto os solos com poucas limitações como aqueles que apresentam riscos permanentes ao cultivo intensivo tiveram sua vegetação nativa removida e foram incorporados ao processo produtivo. Para isso, a adoção de sistemas de manejo que mantêm a estrutura do solo pode ser a chave para a manutenção da qualidade e sustentabilidade dos agrossistemas canavieiros. Assim, o objetivo deste estudo foi avaliar o potencial de uso para cana-de-açúcar e a qualidade estrutural de um Cambissolo Háplico Tb distrófico (CXvbd e um Latossolo Vermelho-Amarelo distrófico (LVAd, no município de Goianésia, GO. Em cada área, realizou-se a classificação das terras quanto à capacidade de uso. Foram coletadas amostras deformadas nas profundidades correspondentes aos horizontes diagnósticos superficiais e subsuperficiais, para caracterização química e físico-hídrica dos solos. Nas profundidades de 0 a 0,05, 0,1 a 0,15 e 0,3 a 0,4 m, foram coletadas amostras indeformadas para determinação da porosidade do solo, da curva de retenção de água, do intervalo hídrico ótimo e da pressão de preconsolidação. O enquadramento dos solos no sistema de capacidade de uso da terra apontou o CXvbd como pertencente à classe IVe, e o LVAd, à classe IIIs. Os resultados das análises dos atributos químicos e físico-hídricos do CXvbd indicaram que o cultivo contínuo com cana-de-açúcar, mesmo com o enquadramento na classe IVe do sistema de capacidade de uso, deve-se à adoção de terraceamento agrícola, além do fato de essa cultura promover pequeno revolvimento do solo e aumentar a cobertura do solo quando colhida crua. O CXvbd apresentou maior disponibilidade de água para as plantas, o que tende a trazer benefícios à cultura. O LVAd, nas condições de estudo, é mais suscetível à compactação, necessitando da adequação do tráfego de máquinas.With the expansion of the sugar/alcohol sector, the native

Berlinale lõpusirgel / Karlo Funk

Index Scriptorium Estoniae

Funk, Karlo, 1971-

2002-01-01

Berliini 52. filmifestivalist, mis algas sakslase Tom Tykweri sisuka mängufilmiga "Taevas". Festivali uue direktori Dieter Kosslicki uuenduseks on saksa filmi endisest tunduvalt suurem osakaal. Eile linastus ametlikult festivali Panorama programmis Peeter Simmi "Head käed". Eesti filmid on esil ka festivali suurel filmiturul, kus Arvo Iho "Karu süda" äratas tähelepanu ja valiti Moskva festivali võistlusprogrammi

Estonski kadr pod juzhnõm nebom / Nikolai Hrustaljov

Index Scriptorium Estoniae

Hrustaljov, Nikolai

2002-01-01

SRÜ ja Baltimaade 11. filmifestivalil Anapas sai parima meesnäitleja preemia Rain Simmul Nika osa eest Arvo Iho mängufilmis "Karu süda", žürii märkis ära Mark Soosaare 8-minutilise "La Paloma", "Avatud videoööde" peapreemia sai Mikk Ranna "Sääsk ja hobune". Festivali parimaks filmiks kuulutati Igor Minajevi "Kuumaastikud" ("Lunnõje poljanõ")

Crescimento e metabolismo em artemísia em função do nível de irradiância Growth and metabolism of feverfew plants in response to the irradiance level

Directory of Open Access Journals (Sweden)

Luciana M de Carvalho

2006-09-01

Full Text Available Artemísia [Tanacetum parthenium (L. Schultz-Bip.] é uma planta medicinal fortemente aromática, cujo princípio ativo característico é a lactona sesquiterpênica partenolídeo. Entre os fatores que afetam o cultivo das plantas medicinais destaca-se a irradiância luminosa. O presente trabalho teve por objetivo verificar efeitos de três níveis de irradiância luminosa (730, 523 e 382 µmol de fótons m-2 s-1 na altura, área foliar, número de folhas, teor de açúcares, de amido e de partenolídeo em artemísia. As plantas cresceram a pleno sol e com 30 e 50% de redução na irradiância por 105 dias. A redução na irradiância foi obtida por meio de sombreamento artificial, com a utilização de telas de polietileno pretas. A redução na irradiância incidente causou aumento na altura e na área foliar total de cada planta, mas não alterou o número de folhas. Houve diminuição nos teores de açúcares e de amido em função do sombreamento, mas os teores de partenolídeo não foram alterados significativamente.Feverfew [Tanacetum parthenium (L. Schultz-Bip.] is a strongly aromatic medicinal plant, whose active principle is the sesquiterpene lactone parthenolide. Irradiance ranks among the most important factors that affect growth of medicinal plants. The effect of three irradiance levels (730, 523 and 382 µmol of fotons m-2 s-1 were assessed on feverfew plants height, leaf area, and leaf number, as well as on the contents of sugar, starch, and parthenolide. Plants grew on full sunshine and under 30 and 50% of irradiance reduction, for 105 days. Irradiance was controlled by shadowing plants with a black polyethylene screen. Reduction on irradiance increased plant height and total leaf area, but had no effect on leaf number. A reduction in sugar and starch contents in association with shadowing was observed. Nevertheless, shadowing did not affect significantly the parthenolide content.

A bioética da proteção e a compaixão laica: o debate moral sobre a eutanásia Bioethics of protection and the laic compassion: the moral debate on euthanasia

Directory of Open Access Journals (Sweden)

Rodrigo Siqueira-Batista

2009-08-01

Full Text Available O debate bioético sobre a eutanásia (“boa morte” vem sendo polarizado, classicamente, entre os princípios da sacralidade da vida - argumentação contra - e da qualidade de vida, representado pelo princípio vicário do respeito à autonomia - argumentação pró. Em ambos os casos, a questão se constrói em torno da pertinência e da legitimidade moral, ou não, de um indivíduo poder decidir sobre o desenlace de sua própria existência, requerendo para si uma boa morte. Sem embargo, a eutanásia pressupõe sempre, além de um eu, um outro, o qual deverá efetuar a ação - ou ater-se à não-ação - que culminará na abreviação da vida. Propor uma discussão acerca deste último ponto, tendo como base os referenciais teóricos da bioética da proteção e o conceito de compaixão laica, é o escopo do presente ensaio.The bioethical debate on euthanasia (“good death” has been classically polarized between the principles of sacredness of life - the argumentation against - and the quality of life, represented by the vicarious principle of respect for autonomy - the argumentation in favor. In both cases the question is built around the pertinence and moral legitimacy - or not - of the individual possibility to decide about the termination of one’s own existence, demanding for oneself a good death. Undoubtedly, euthanasia always implies besides the self, the other, who will either carry out the action - or hold to non-action - culminating in the abbreviation of life. To propose a discussion about this last referred issue, based on the bioethics of protection theoretical references and the concept of laic compassion is the scope of the present essay.

Evaluating the use of Social Impact Assessment in the context of agricultural development projects in Iran

International Nuclear Information System (INIS)

Ahmadvand, Mostafa; Karami, Ezatollah; Zamani, Gholam Hossein; Vanclay, Frank

2009-01-01

The utilisation of Social Impact Assessment (SIA) in Iran is analysed in terms of its policy context and its application in practice. Five case studies where SIA was employed in conjunction with Environmental Impact Assessments (EIA) for agricultural development projects are evaluated. In addition, the performance of the policy context is assessed. This research revealed that there are legal and institutional constraints to the effective functioning of SIA in Iran, and that there are deficiencies in the operating guidelines. There were serious problems associated with the way SIA was undertaken in all five case studies. Recommendations to improve the policy framework for the conduct of SIA are made. The recommendations advocate for a higher profile of SIA within legislation, for social issues to have greater emphasis in official guidelines for the conduct of EIA and SIA, and for a range of measures to increase the professionalism of SIA practice.

UTILIZAÇÃO DO SOFTWARE MAPGEO 2010 COMO RECURSO DIDÁTICO NO ESTUDO DAS SUPERFÍCIES E REFERENCIAIS GEODÉSICOS ADOTADOS EM GEODÉSIA

Directory of Open Access Journals (Sweden)

Maria Lígia Chuerubim

2014-07-01

Full Text Available Este artigo visa realizar uma breve abordagem dos principais conceitos, aplicações e técnicas de posicionamento espacial GNSS (Global Navigation Satellite System como, por exemplo, o GPS (Global Positioning System, envolvidas na obtenção da ondulação geoidal e na conversão entre as altitudes geométricas (elipsoidais e científicas (ortométricas. A utilização de modelos matemáticos que relacionam as altitudes ortométricas e geométrica ao geóide possibilitam a obtenção da ondulação geoidal, que reflete a distribuição de massas no interior da superfície terrestre. O cálculo da ondulação do geóide por GPS pode ser realizada por meio do aplicativo computacional MAPGEO2010, disponibilizado pelo IBGE, que permite obter a ondulação geoidal para um ou mais pontos de forma rápida e prática, requerendo conhecimentos fundamentais associados às superfícies (física, geoidal e elipsoidal e referenciais adotados em Geodésia como o SIRGAS2000 (Sistema de Referência Geocêntrico para as Américas e o SAD69 (South American Datum 1969, possibilitando ao usuário analisar de forma mais consistente os resultados obtidos.

Koolileht reklaamib hiliseid lokaale / Marta Karu

Index Scriptorium Estoniae

Karu, Marta

1999-01-01

Tamme gümnaasiumi ajalehes 'Tammepress' on esiküljele paigutatud Tartu ärimehele Rein Kilgile kuuluva Zum-Zumi-nimelise lokaali reklaam. Pildil joovad loomad õlut ja viina ning suitsetavad. Samas numbris reklaamitakse koolilastele R. Kilgi suurprojekti Ammende villat ja lõbusõidulaeva 'Pegasus'.

Ühest kohalikust naisseltsist / Lembit Karu

Index Scriptorium Estoniae

Karu, Lembit, 1948-

2013-01-01

Kirjutise eesmärgiks on tutvustada Eesti Põllumajandusmuuseumis Roela-Altserva Maanaiste Seltsi kohta säilitatavaid dokumente (625 säilikut) ja iseloomustada põhilisi tegevussuundi, et aidata paremini mõista seltsi osatähtsust maaelus

Kindlasti... võib-olla / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2008-01-01

Lühiarvustus komöödiafilmist "Kindlasti... võib-olla" ("Definitely, Maybe") : režissöör Adam Brooks : osades Abigail Breslin, Ryan Reynolds : Suurbritannia - Ameerika Ühendriigid - Prantsusmaa 2008

Kõristid Vene karu tagumikus / Igor Taro

Index Scriptorium Estoniae

Taro, Igor

2008-01-01

Venemaa vajadus Afganistani suunal NATOga koostööd teha ei jää alla alliansi vajadusele Venemaa abi järele, kuna Afganistan kujutab endast narkootikumide eksportijat ja terroriohtu otse Venemaa külje all. Kaart: Afganistan on Venemaale eluliselt sama tähtis kui NATO-le

Kui Julia armastab Juliat / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2007-01-01

Inglise 3-osaline draamasari "Apelsinid pole ainsad viljad" ("Oranges Are Not the Only Fruit"), stsenarist oma esikromaani alusel Jeanette Winterson, peaosas Charlotte Coleman. Sama ka : Teleleht nr. 45, lk. 9 : ill

Must maja, valge aed / Mihkel Karu

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2012-01-01

Laagris 2010. aastal valminud eramust. Tänavapoolne aed on valatud betoonist. Arhitektid: Peeter Pere, Urmas Muru, Anna-Maria Erik (AB Muru & Pere). Sisearhitektid: Katrin Kaevats, Peeter Pere, Urmas Muru. Projekt. 2008. Peeter Pere kommentaar

Kõik teed viivad Rooma ehk kolm võimalust efektiivsuse tõstmiseks / Meredith Belbin

Index Scriptorium Estoniae

Belbin, Meredith

2008-01-01

Autor selgitab, kuidas luua efektiivselt toimivat meeskonda, kus töörollid oleksid tasakaalus ning toimuks efektiivne ja kiire tegutsemine. Joonised: Töörollid ja nende sisu; Töörollide värvikaart; Ässa mudel; Organisatsioon nagu lihavõttemuna. Vt. ka Sander Karu. Boonus - enne kokkulepitud eesmärk ja siis tasu lk. 30-31; Eva Palu. Pigista oma ärist maksimum välja lk. 32-34

Combinations of Quality and Frequency of Immunization Activities to Stop and Prevent Poliovirus Transmission in the High-Risk Area of Northwest Nigeria.

Directory of Open Access Journals (Sweden)

Radboud J Duintjer Tebbens

Full Text Available Frequent supplemental immunization activities (SIAs with the oral poliovirus vaccine (OPV represent the primary strategy to interrupt poliovirus transmission in the last endemic areas.Using a differential-equation based poliovirus transmission model tailored to high-risk areas in Nigeria, we perform one-way and multi-way sensitivity analyses to demonstrate the impact of different assumptions about routine immunization (RI and the frequency and quality of SIAs on population immunity to transmission and persistence or emergence of circulating vaccine-derived polioviruses (cVDPVs after OPV cessation.More trivalent OPV use remains critical to avoid serotype 2 cVDPVs. RI schedules with or without inactivated polio vaccine (IPV could significantly improve population immunity if coverage increases well above current levels in under-vaccinated subpopulations. Similarly, the impact of SIAs on overall population immunity and cVDPV risks depends on their ability to reach under-vaccinated groups (i.e., SIA quality. Lower SIA coverage in the under-vaccinated subpopulation results in a higher frequency of SIAs needed to maintain high enough population immunity to avoid cVDPVs after OPV cessation.National immunization program managers in northwest Nigeria should recognize the benefits of increasing RI and SIA quality. Sufficiently improving RI coverage and improving SIA quality will reduce the frequency of SIAs required to stop and prevent future poliovirus transmission. Better information about the incremental costs to identify and reach under-vaccinated children would help determine the optimal balance between spending to increase SIA and RI quality and spending to increase SIA frequency.

Roles of social impact assessment practitioners

International Nuclear Information System (INIS)

Wong, Cecilia H.M.; Ho, Wing-chung

2015-01-01

The effectiveness of social impact assessment (SIA) hinges largely on the capabilities and ethics of the practitioners, yet few studies have dedicated to discuss the expectations for these professionals. Recognising this knowledge gap, we employed the systemic review approach to construct a framework of roles of SIA practitioners from literature. Our conceptual framework encompasses eleven roles, namely project manager of SIA, practitioner of SIA methodologies, social researcher, social strategy developer, social impact management consultant, community developer, visionary, public involvement specialist, coordinator, SIA researcher, and educator. Although these roles have been stratified into three overarching categories, the project, community and SIA development, they are indeed interrelated and should be examined together. The significance of this study is threefold. First, it pioneers the study of the roles of SIA practitioners in a focused and systematic manner. Second, it informs practitioners of the expectations of them thereby fostering professionalism. Third, it prepares the public for SIAs by elucidating the functions and values of the assessment. - Highlights: • We adopt systematic review to construct a framework of roles of social impact assessment (SIA) practitioners from literature. • We use three overarching categorises to stratify the eleven roles we proposed. • This work is a novel attempt to study the work as a SIA practitioner and build a foundation for further exploration. • The framework informs practitioners of the expectations on them thus reinforcing professionalism. • The framework also prepares the public for SIAs by elucidating the functions and values of the assessment

Combinations of Quality and Frequency of Immunization Activities to Stop and Prevent Poliovirus Transmission in the High-Risk Area of Northwest Nigeria.

Science.gov (United States)

Duintjer Tebbens, Radboud J; Pallansch, Mark A; Wassilak, Steven G F; Cochi, Stephen L; Thompson, Kimberly M

2015-01-01

Frequent supplemental immunization activities (SIAs) with the oral poliovirus vaccine (OPV) represent the primary strategy to interrupt poliovirus transmission in the last endemic areas. Using a differential-equation based poliovirus transmission model tailored to high-risk areas in Nigeria, we perform one-way and multi-way sensitivity analyses to demonstrate the impact of different assumptions about routine immunization (RI) and the frequency and quality of SIAs on population immunity to transmission and persistence or emergence of circulating vaccine-derived polioviruses (cVDPVs) after OPV cessation. More trivalent OPV use remains critical to avoid serotype 2 cVDPVs. RI schedules with or without inactivated polio vaccine (IPV) could significantly improve population immunity if coverage increases well above current levels in under-vaccinated subpopulations. Similarly, the impact of SIAs on overall population immunity and cVDPV risks depends on their ability to reach under-vaccinated groups (i.e., SIA quality). Lower SIA coverage in the under-vaccinated subpopulation results in a higher frequency of SIAs needed to maintain high enough population immunity to avoid cVDPVs after OPV cessation. National immunization program managers in northwest Nigeria should recognize the benefits of increasing RI and SIA quality. Sufficiently improving RI coverage and improving SIA quality will reduce the frequency of SIAs required to stop and prevent future poliovirus transmission. Better information about the incremental costs to identify and reach under-vaccinated children would help determine the optimal balance between spending to increase SIA and RI quality and spending to increase SIA frequency.

Roles of social impact assessment practitioners

Energy Technology Data Exchange (ETDEWEB)

Wong, Cecilia H.M., E-mail: ceciliawonghm@gmail.com; Ho, Wing-chung, E-mail: wingcho@cityu.edu.hk

2015-01-15

The effectiveness of social impact assessment (SIA) hinges largely on the capabilities and ethics of the practitioners, yet few studies have dedicated to discuss the expectations for these professionals. Recognising this knowledge gap, we employed the systemic review approach to construct a framework of roles of SIA practitioners from literature. Our conceptual framework encompasses eleven roles, namely project manager of SIA, practitioner of SIA methodologies, social researcher, social strategy developer, social impact management consultant, community developer, visionary, public involvement specialist, coordinator, SIA researcher, and educator. Although these roles have been stratified into three overarching categories, the project, community and SIA development, they are indeed interrelated and should be examined together. The significance of this study is threefold. First, it pioneers the study of the roles of SIA practitioners in a focused and systematic manner. Second, it informs practitioners of the expectations of them thereby fostering professionalism. Third, it prepares the public for SIAs by elucidating the functions and values of the assessment. - Highlights: • We adopt systematic review to construct a framework of roles of social impact assessment (SIA) practitioners from literature. • We use three overarching categorises to stratify the eleven roles we proposed. • This work is a novel attempt to study the work as a SIA practitioner and build a foundation for further exploration. • The framework informs practitioners of the expectations on them thus reinforcing professionalism. • The framework also prepares the public for SIAs by elucidating the functions and values of the assessment.

Kinetics of interstitial defects in α-Fe: The effect from uniaxial stress

Energy Technology Data Exchange (ETDEWEB)

Kang, Changwoo [Department of Nuclear Engineering, Texas A& M University, College Station, TX 77843 (United States); Wang, Qingyu [College of Nuclear Science and Technology, Harbin Engineering University, Harbin 150001 (China); Shao, Lin, E-mail: lshao@tamu.edu [Department of Nuclear Engineering, Texas A& M University, College Station, TX 77843 (United States)

2017-03-15

Understanding defect kinetics in a stress field is important for multiscale modeling of materials degradation of nuclear materials. By means of molecular dynamics and molecular statics simulations, we calculate formation and migration energies of self-interstitial atoms (SIA) and SIA clusters (up to size of 5 interstitials) in alpha Fe and identify their stable configurations under uniaxial tensile strains. By applying uniaxial stress along [111], <111> oriented single SIA defects become more stable than <110> oriented SIA, which is opposite to stress-free condition. Diffusion of single SIA defects under [111] tensile stress is facilitated along [111] direction and the diffusion becomes one dimensional (1D). For SIA clusters, their diffusion under zero stress has gradual transition from three dimensional (3D) for small clusters to one dimensional (1D) for large clusters. Under the tensile stress along [111], the 3D to 1D transition is accelerated. For large SIA clusters, the stress effect is quickly saturated with less diffusivity enhancement in comparison with small SIA clusters.

Controlling measles using supplemental immunization activities: a mathematical model to inform optimal policy.

Science.gov (United States)

Verguet, Stéphane; Johri, Mira; Morris, Shaun K; Gauvreau, Cindy L; Jha, Prabhat; Jit, Mark

2015-03-03

The Measles & Rubella Initiative, a broad consortium of global health agencies, has provided support to measles-burdened countries, focusing on sustaining high coverage of routine immunization of children and supplementing it with a second dose opportunity for measles vaccine through supplemental immunization activities (SIAs). We estimate optimal scheduling of SIAs in countries with the highest measles burden. We develop an age-stratified dynamic compartmental model of measles transmission. We explore the frequency of SIAs in order to achieve measles control in selected countries and two Indian states with high measles burden. Specifically, we compute the maximum allowable time period between two consecutive SIAs to achieve measles control. Our analysis indicates that a single SIA will not control measles transmission in any of the countries with high measles burden. However, regular SIAs at high coverage levels are a viable strategy to prevent measles outbreaks. The periodicity of SIAs differs between countries and even within a single country, and is determined by population demographics and existing routine immunization coverage. Our analysis can guide country policymakers deciding on the optimal scheduling of SIA campaigns and the best combination of routine and SIA vaccination to control measles. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Causas de morte e razões para eutanásia de cães da Mesorregião do Centro Ocidental Rio-Grandense (1965-2004) Causes of death and reasons for euthanasia in dogs from the midland region of the Midwest of Rio Grande do Sul State, Brazil (1965-2004)

OpenAIRE

Rafael A. Fighera; Tatiana M. Souza; Marcia C. Silva; Juliana S. Brum; Dominguita L. Graça; Glaucia D. Kommers; Luiz F. Irigoyen; Claudio S.L. Barros

2008-01-01

Este estudo teve como objetivo principal determinar a prevalência das doenças que culminam em morte ou que fazem com que os cães da Mesorregião do Centro Ocidental Rio-Grandense sejam submetidos à eutanásia. Para isso, foram revisados todos os protocolos de necropsia de cães, arquivados no Laboratório de Patologia Veterinária (LPV) da Universidade Federal de Santa Maria (UFSM), realizadas entre janeiro de 1965 e dezembro de 2004. Nos arquivos do LPV-UFSM foram encontrados 4.844 protocolos de ...

Chemical Synthesis and Evaluation of a Disialic Acid-Containing Dextran Polymer as an Inhibitor for the Interaction between Siglec 7 and Its Ligand.

Science.gov (United States)

Yamaguchi, Sho; Yoshimura, Atsushi; Yasuda, Yu; Mori, Airi; Tanaka, Hiroshi; Takahashi, Takashi; Kitajima, Ken; Sato, Chihiro

2017-07-04

A new sialic acid (Sia)-containing glycopolymer-a fluorescent probe with high-density disialic acid (diSia) on the surface of polysaccharide dextran (diSia-Dex)-was synthesized as a key molecule to regulate the Sia recognition lectins, Siglecs, that are involved in the immune system. According to our original methods, diSia was synthesized by α-selective sialylation, and a dextran template possessing terminal acetylenes and amino groups was prepared. A diSia and a fluorescent molecule were subsequently introduced to surface-modified dextran by Hüisgen reaction and amidation, respectively. The modulatory activity of Siglec7 was evaluated by using synthetic probes. DiSia-Dex showed high binding avidity toward Siglec7, with a K D value of 5.87×10 -10  m, and a high inhibitory activity for the interaction between Siglec7 and a ligand (GD3), with a IC 50 value of 1.0 nm. Notably, diSia-Dex was able to release Siglec7 from the pre-existing Siglec7-GD3 complex, possibly due to its unique properties of a slow dissociation rate and a high association rate. Together, these data show that diSia-Dex can be widely applicable as a modulator of Siglec7 functions. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Polysialic acid immobilized on silanized glass surfaces: a test case for its use as a biomaterial for nerve regeneration.

Science.gov (United States)

Steinhaus, Stephanie; Stark, Yvonne; Bruns, Stephanie; Haile, Yohannes; Scheper, Thomas; Grothe, Claudia; Behrens, Peter

2010-04-01

The immobilization of polysialic acid (polySia) on glass substrates has been investigated with regard to the applicability of this polysaccharide as a novel, biocompatible and bioresorbable material for tissue engineering, especially with regard to its use in nerve regeneration. PolySia, a homopolymer of alpha-2,8-linked sialic acid, is involved in post-translational modification of the neural cell adhesion molecule (NCAM). The degradation of polySia can be controlled which makes it an interesting material for coating and for scaffold construction in tissue engineering. Here, we describe the immobilization of polySia on glass surfaces via an epoxysilane linker. Whereas glass surfaces will not actually be used in nerve regeneration scaffolds, they provide a simple and efficient means for testing various methods for the investigation of immobilized polySia. The modified surfaces were investigated with contact angle measurements and the quantity of immobilized polySia was examined by the thiobarbituric acid assay and a specific polySia-ELISA. The interactions between the polySia-modified surface and immortalized Schwann cells were evaluated via cell adhesion and cell viability assays. The results show that polySia can be immobilized on glass surfaces via the epoxysilane linker and that surface-bound polySia has no toxic effects on Schwann cells. Therefore, as a key substance in the development of vertebrates and as a favourable substrate for the cultivation of Schwann cells, it offers interesting features for the use in nerve guidance tubes for treatment of peripheral nerve injuries.

Mechanisms for decoration of dislocations by small dislocation loops under cascade damage conditions

DEFF Research Database (Denmark)

Trinkaus, H.; Singh, B.N.; Foreman, A.J.E.

1997-01-01

. This effect may arise as a result of either (a) migration and enhanced agglomeration of single SIAs in the form of loops in the strain field of the dislocation or (b) glide and trapping of SIA loops (produced directly in the cascades) in the strain field of the dislocation, In the present paper, both...... of these possibilities are examined. It is shown that the strain field of the dislocation causes a SIA depletion in the compressive as well as in the dilatational region resulting in a reduced rather than enhanced agglomeration of SIAs. (SIA depletion may, however, induce enhanced vacancy agglomeration near dislocations...

Impact of an Intervention to Use a Measles, Rubella, and Polio Mass Vaccination Campaign to Strengthen Routine Immunization Services in Nepal.

Science.gov (United States)

Wallace, Aaron S; Bohara, Rajendra; Stewart, Steven; Subedi, Giri; Anand, Abhijeet; Burnett, Eleanor; Giri, Jagat; Shrestha, Jagat; Gurau, Suraj; Dixit, Sameer; Rajbhandari, Rajesh; Schluter, W William

2017-07-01

The potential to strengthen routine immunization (RI) services through supplementary immunization activities (SIAs) is an important benefit of global measles and rubella elimination and polio eradication strategies. However, little evidence exists on how best to use SIAs to strengthen RI. As part the 2012 Nepal measles-rubella and polio SIA, we developed an intervention package designed to improve RI processes and evaluated its effect on specific RI process measures. The intervention package was incorporated into existing SIA activities and materials to improve healthcare providers' RI knowledge and practices throughout Nepal. In 1 region (Central Region) we surveyed the same 100 randomly selected health facilities before and after the SIA and evaluated the following RI process measures: vaccine safety, RI planning, RI service delivery, vaccine supply chain, and RI data recording practices. Data collection included observations of vaccination sessions, interviews with the primary healthcare provider who administered vaccines at each facility, and administrative record reviews. Pair-matched analytical methods were used to determine whether statistically significant changes in the selected RI process measures occurred over time. After the SIA, significant positive changes were measured in healthcare provider knowledge of adverse events following immunization (11% increase), availability of RI microplans (+17%) and maps (+12%), and awareness of how long a reconstituted measles vial can be used before it must be discarded (+14%). For the SIA, 42% of providers created an SIA high-risk villages list, and >50% incorporated this information into RI outreach session site planning. Significant negative changes occurred in correct knowledge of measles vaccination contraindications (-11%), correct definition for a measles outbreak (-21%), and how to treat a child with a severe adverse event following immunization (-10%). Twenty percent of providers reported cancelling ≥1 RI

A distanásia como geradora de dilemas éticos nas Unidades de Terapia Intensiva: considerações sobre a participação dos enfermeiros La distanasia como generadora de dilemas éticos en las Unidades deTerapia Intensiva: algunos aspectos a cerca de lo envolvimiento de los enfermeros Disthanasia as an ethical dilemma at the Intensive Care Units: considerations about nurses involvement

Directory of Open Access Journals (Sweden)

Maria Cecilia Toffoletto

2005-09-01

Full Text Available A distanásia apresenta-se como uma das fontes geradoras de dilemas éticos nas Unidades de Terapia Intensiva (UTI. Discute-se o contexto que favorece a prática da distanásia nesse ambiente, com ênfase na utilização excessiva do suporte tecnológico. Tecemos comentários sobre a participação dos familiares e profissionais envolvidos, principalmente médicos e enfermeiros, considerando-se o papel sócio-profissional atribuído a cada um. Pretende-se com as considerações apresentadas, fornecer subsídios para a reflexão do tema, com vistas a uma participação mais ativa dos enfermeiros de UTI nos dilemas éticos relacionados à distanásia.La distanasia se presenta como una de las fuentes generadoras de los dilemas éticos en las Unidades de Terapia Intensiva (UTI Discute el contexto que favorece la práctica de la distanasia en este ambiente, con énfasis en la utilización excesiva del arsenal tecnologico. Además de los comentarios sobre la posición de los familiares y de los profesionales involucrados, principalmente los médicos y enfermeros, se consideró el papel socio-profesional que se atribuye a cada uno. Para finalizar, los profesionales del area son estimulados a refletir sobre el tema y los enfermeros a participar de manera más activa en las discusiones de los dilemas éticos relacionados a la distanasia.Disthanasia is conceptualized and presented as an ethical dilemma in Intensive Care Units (ICU. The context favoring the disthanasia practice on this environment focusing the excessive use of technological devices will be discussed. The study will approach the family, physician and nurse’s participation in the situations, considering the social and professional role of each one. This study aims to provide support for healthcare professionals to reflect on this subject, aiming the nurse’s more effective participation on ethical dilemmas related to disthanasia.

How social impact assessment can contribute to conflict management

International Nuclear Information System (INIS)

Prenzel, Paula V.; Vanclay, Frank

2014-01-01

The potential for conflict is omnipresent in all projects, and even in all human interactions, and conflict itself leads to many second-order social impacts. This article examines the contribution of the methodological approach used in social impact assessment (SIA) to conflict management. We view conflict as a process that has its own dynamic, and is to be expected in all situations. By using game theory (prisoner's dilemma), we describe and conceptualize this process and highlight the importance of communication in managing conflict. We demonstrate the potential use of SIA in preventing, managing and resolving conflict. Emphasis is placed on the participatory character of SIA and the role of public media. In contrast to existing literature, our focus is not restricted to the typical fields of study of SIA (e.g. environmental conflicts), but understands conflict itself as a field of application. In this sense, conflict-sensitive SIA can be understood both as an extension to the SIA tool kit and a broadening of the scope of SIA application. -- Highlights: • Conflict is omnipresent and creates both positive and negative social impacts. • Conflict itself represents a possible field of application for SIA. • Conflict escalation is a process that can be modeled in a game-theoretic framework. • There needs to be concerted effort to prevent escalation to avoid harmful outcomes. • Conflict-sensitive SIA can support conflict management and sustainable resolution

How social impact assessment can contribute to conflict management

Energy Technology Data Exchange (ETDEWEB)

Prenzel, Paula V., E-mail: p.v.prenzel@student.rug.nl; Vanclay, Frank, E-mail: frank.vanclay@rug.nl

2014-02-15

The potential for conflict is omnipresent in all projects, and even in all human interactions, and conflict itself leads to many second-order social impacts. This article examines the contribution of the methodological approach used in social impact assessment (SIA) to conflict management. We view conflict as a process that has its own dynamic, and is to be expected in all situations. By using game theory (prisoner's dilemma), we describe and conceptualize this process and highlight the importance of communication in managing conflict. We demonstrate the potential use of SIA in preventing, managing and resolving conflict. Emphasis is placed on the participatory character of SIA and the role of public media. In contrast to existing literature, our focus is not restricted to the typical fields of study of SIA (e.g. environmental conflicts), but understands conflict itself as a field of application. In this sense, conflict-sensitive SIA can be understood both as an extension to the SIA tool kit and a broadening of the scope of SIA application. -- Highlights: • Conflict is omnipresent and creates both positive and negative social impacts. • Conflict itself represents a possible field of application for SIA. • Conflict escalation is a process that can be modeled in a game-theoretic framework. • There needs to be concerted effort to prevent escalation to avoid harmful outcomes. • Conflict-sensitive SIA can support conflict management and sustainable resolution.

Significado e Percepção de Eutanásia Sob a Óptica de Acadêmicos de Medicina de Uma Cidade Sul Mineira / Significance and Perception of Euthanasia under the Vision of Medical Students in a City in the South of Minas Gerais

Directory of Open Access Journals (Sweden)

Agnes Aparecida dos Santos

2015-12-01

Full Text Available Objetivo: Identificar o significado e a percepção de eutanásia para os acadêmicos de medicina de uma cidade sul mineira. Materiais e Métodos: Trata-se de uma pesquisa exploratória, descritiva, qualitativa e transversal. Como método de estudo, foi utilizado o Discurso do Sujeito Coletivo que tem como base a Teoria das Representações Sociais. Resultados: Mostraram que as ideias centrais “Provocar a morte” e “Sou contra” foram de maior prevalência para os acadêmicos de medicina. Conclusão: Depreende-se que é preciso incentivar os profissionais de saúde e acadêmicos a fazerem novas pesquisas sobre o assunto e oferecer subsídios às instituições de saúde para elaborarem junto a Comissão de Ética maneiras de tratar assuntos sobre a eutanásia e os cuidados com os pacientes no final da vida. Objective: Identify the meaning and sense of euthanasia to medical students in a city in the South of Minas Gerais. Materials and Methods: It is a exploratory, descriptive, qualitative and cross-sectional research. As a study method it was used the Discourse of the Collective Subject which is based in the Social Representations Theory. Results: demonstrated that the central ideas “To cause the death” and “I’m against” were the most prevalent among the medical students. Conclusion: It may be concluded that it is necessary to encourage health-care professionals and students to make new researches about this subject and offer subsidies to health facilities in onder to develop, with the ethics committee, ways to deal with topics about euthanasia and care of the terminal patients.

The nursing’s scientific production on euthanasia: integrative literature review

Directory of Open Access Journals (Sweden)

Caren Camargo do Espírito Santo

2014-07-01

Full Text Available Objetivos: Descrever como a eutanásia tem sido abordada nas publicações científicas nacionais realizadas por enfermeiros e discutir sobre os aspectos bioéticos descritos relacionados à eutanásia. Método: Revisão integrativa de literatura nas bases de dados BDENF, SciELO e LILACS, por meio dos descritores eutanásia e enfermagem, utilizando-se textos completos e em português. Resultados: Foram encontrados 24 artigos, dos quais 06 possuíam texto completo. Destes, foram selecionadas 04 publicações que atenderam aos critérios de inclusão e estabeleceram relação consistente com a temática. Conclusão: Temática pouco explorada no cenário nacional por pesquisadores da enfermagem. Os estudos encontrados não versavam exatamente sobre a eutanásia apenas, mas sobre terminalidade da vida e cuidado paliativo, distanásia, ortotanásia, e falavam de outros atores envolvidos no processo de decisão no fim da vida. Descritores: Eutanásia, Enfermagem, Bioética.

Simm jagas Anapas piitsa ja präänikut / Peeter Simm ; interv. Tiit Tuumalu

Index Scriptorium Estoniae

Simm, Peeter, 1953-

2002-01-01

Žürii liige SRÜ ja Baltimaade 11. filmifestivalil Anapas, eesti režissöör P. Simm festivalist ja eesti filmi tasemest endiste nõukogude vabariikide tänaste tegijate kõrval. Parima meesnäitleja preemia sai Rain Simmul Nika osa eest Arvo Iho mängufilmis "Karu süda". Videoprogrammi grand prix sai Mikk Ranna animafilm "Sääsk ja hobune", samas märgiti ära ka Mark Soosaare "La Paloma"

ERKÜ valimiste tulemused

Index Scriptorium Estoniae

2006-01-01

8. aprilli koosolekul kinnitas valimiste peakomitee XIX Esinduskogu liikmed: Mati Kõiva, Ylo Anson, Juhan Simonson, Airi Vaga, Gilda M. Karu, Taavo Virkhaus, Marju Rink-Abel, Markus Vaga, Eric Suuberg, Endel Reinpõld, Jaak Juhansoo, Ülle Ederma, Lya Karm, Heino Jõgis, Kersti Linask, Jaak Rakfeldt, Erik Puskar, Jüri Linask, Viiu Vanderer, Andres Kurrik, Mati Valdek Laan, Ilmar Vanderer, Henno Uus, Jüri Tults, Urmas Wompa, Astrid Jaanson, Jüri Virkus, Lilian G. G. Bein, Tiina Harris, Tõnu Vanderer

O cinema como instrumento cidático para a abordagem de problemas bioéticos: uma reflexão sobre a eutanásia

Directory of Open Access Journals (Sweden)

Anielle Avelina Dantas

Full Text Available O ensino da ética é necessário à formação dos alunos do curso de Medicina, pois o cuidado da saúde dos indivíduos e das populações pressupõe ações e decisões que devem ser permanentemente avaliadas de modo racional com respeito às suas reais e efetivas repercussões. As artes cinematográficas podem estimular a avaliação crítica e o entendimento efetivo das narrativas e necessidades únicas dos pacientes. O objetivo do presente estudo é mostrar que a análise estruturada de um filme comercial pode constituir uma atividade instrucional facilitadora para a concretização de objetivos educacionais relativos ao ensino da bioética e, em particular, dos problemas morais concernentes à eutanásia. Foi realizada uma interpretação macro e microanalítica do filme Mar Adentro e identificaram-se exemplos de situações e oportunidades de ensino-aprendizagem. O critério de seleção das cenas se pautou na capacidade de estas revelarem conteúdos e situações que possam estimular uma reflexão acerca dos dilemas morais/bioéticos relativos ao direito à vida. A exibição de um filme seguida da discussão de cenas pode ser utilizada como instrumento pedagógico significante para atingir objetivos educacionais humanísticos dos currículos dos cursos de Medicina.

Impact of measles supplementary immunization activities on reaching children missed by routine programs.

Science.gov (United States)

Portnoy, Allison; Jit, Mark; Helleringer, Stéphane; Verguet, Stéphane

2018-01-02

Measles supplementary immunization activities (SIAs) are vaccination campaigns that supplement routine vaccination programs with a recommended second dose opportunity to children of different ages regardless of their previous history of measles vaccination. They are conducted every 2-4 years and over a few weeks in many low- and middle-income countries. While SIAs have high vaccination coverage, it is unclear whether they reach the children who miss their routine measles vaccine dose. Determining who is reached by SIAs is vital to understanding their effectiveness, as well as measure progress towards measles control. We examined SIAs in low- and middle-income countries from 2000 to 2014 using data from the Demographic and Health Surveys. Conditional on a child's routine measles vaccination status, we examined whether children participated in the most recent measles SIA. The average proportion of zero-dose children (no previous routine measles vaccination defined as no vaccination date before the SIA) reached by SIAs across 14 countries was 66%, ranging from 28% in São Tomé and Príncipe to 91% in Nigeria. However, when also including all children with routine measles vaccination data, this proportion decreased to 12% and to 58% when imputing data for children with vaccination reported by the mother and vaccination marks on the vaccination card across countries. Overall, the proportions of zero-dose children reached by SIAs declined with increasing household wealth. Some countries appeared to reach a higher proportion of zero-dose children using SIAs than others, with proportions reached varying according to the definition of measles vaccination (e.g., vaccination dates on the vaccination card, vaccination marks on the vaccination card, and/or self-reported data). This suggests that some countries could improve their targeting of SIAs to children who miss other measles vaccine opportunities. Across all countries, SIAs played an important role in reaching

Approximations and Implementations of Nonlinear Filtering Schemes.

Science.gov (United States)

1988-02-01

sias k an Ykar repctively the input and the output vectors. Asfold. First, there are intrinsic errors, due to explained in the previous section, the...e.g.[BV,P]). In the above example of a a-algebra, the distributive property SIA (S 2vS3) - (SIAS2)v(SIAS3) holds. A complete orthocomplemented...process can be approximated by a switched Control Systems: Stochastic Stability and parameter process depending on the aggregated slow Dynamic Relaibility

Sviluppo di metodi analitici per determinazioni affidabili in campo ambientale ed alimentare

OpenAIRE

Notardonato, Ivan

2010-01-01

La presenza di sostanze tossiche nei prodotti alimentari è stato da sempre un problema di grande rilevanza e influenza sociale sia per la natura sia per l’uomo. Nel corso degli anni sono state studiate e caratterizzate diverse sostanze presenti nell’ambiente, molte catalogate come tossiche, derivanti sia da fonti naturali sia da fonti industriali. Alcune di queste sostanze sono state ritenute particolarmente pericolose e quindi è nata l’esigenza di monitorarle e/o di cercare di limitarne il ...

Determinação de baixas concentrações de cobre em águas naturais por espectrofotometria de absorção atômica em chama usando um sistema SIA com uma coluna de poli(etilenimina

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Costa Rui Cerdeira de Campos

2001-01-01

Full Text Available This paper describes a sequential injection analysis (SIA set-up coupled to a flame atomic absorption spectrometer (FAAS to accomplish the determination of low concentrations of copper in drinking waters. Copper is first retained under neutral media in an on-line 29x1.6 mm column filled with poly(ethylenimine immobilised on silica gel. The retained analyte is then eluted by flowing through the column 250 mL of a nitric acid solution. The selection of 3.85 ml of sample enabled to obtain a detection limit of 0.27 mug/L and a sampling rate of about 24 samples/h. There was a good agrement between the results of 12 samples furnished by the proposed procedure and by electrothermal atomic absorption spectrometry. Repeatability assessment gave a relative standard deviation of 1.3 % after ten replicate analysis of a sample containing about 70 mug/L in copper..

Epilepsy-associated long-term mortality after aneurysmal subarachnoid hemorrhage.

Science.gov (United States)

Huttunen, Jukka; Lindgren, Antti; Kurki, Mitja I; Huttunen, Terhi; Frösen, Juhana; Koivisto, Timo; von Und Zu Fraunberg, Mikael; Immonen, Arto; Jääskeläinen, Juha E; Kälviäinen, Reetta

2017-07-18

To elucidate the epilepsy-associated causes of death and subsequent excess long-term mortality among 12-month survivors of subarachnoid hemorrhage from saccular intracranial aneurysm (SIA-SAH). The Kuopio SIA Database (kuopioneurosurgery.fi) includes all SIA-SAH patients admitted to the Kuopio University Hospital from its defined catchment population in Eastern Finland. The study cohort consists of 779 patients, admitted from 1995 to 2007, who were alive at 12 months after SIA-SAH. Their use of reimbursable antiepileptic drugs and the causes of death (ICD-10) were fused from the Finnish national registries from 1994 to 2014. The 779 12-month survivors were followed up until death (n = 197) or December 31, 2014, a median of 12.0 years after SIA-SAH. Epilepsy had been diagnosed in 121 (15%) patients after SIA-SAH, and 34/121 (28%) had died at the end of follow-up, with epilepsy as the immediate cause of death in 7/34 (21%). In the 779 patients alive at 12 months after SIA-SAH, epilepsy was an independent risk factor for mortality (hazard ratio 1.8, 95% confidence interval 1.1-3.0). Comorbid epilepsy in 12-month survivors of SIA-SAH is associated with increased risk of death in long-term follow-up. Survivors of SIA-SAH require long-term dedicated follow-up, including identification and effective treatment of comorbid epilepsy to prevent avoidable deaths. Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.

Cerebral signal intensity abnormalities on T2-weighted MR images in HIV patients with highly active antiretroviral therapy: relationship with clinical parameters and interval changes.

Science.gov (United States)

Hanning, Uta; Husstedt, Ingo W; Niederstadt, Thomas-Ulrich; Evers, Stefan; Heindel, Walter; Kloska, Stephan P

2011-09-01

The aim of this study was to assess the relationship between immune state and cerebral signal intensity abnormalities (SIAs) on T2-weighted magnetic resonance images in subjects with human immunodeficiency virus type 1 infection and highly active antiretroviral therapy. Thirty-two subjects underwent a total of 109 magnetic resonance studies. The presence of human immunodeficiency virus-associated neurocognitive disorder, categorized CD4(+) T lymphocyte count, and plasma viral load were assessed for relationship with the severity and interval change of SIAs for different anatomic locations of the brain. Subjects with multifocal patterns of SIAs had CD4(+) cell counts < 200 cells/μL in 66.0%, whereas subjects with diffuse patterns of SIAs had CD4(+) cell counts < 200 cells/μL in only 31.4% (P < .001). Subjects without SIAs in the basal ganglia had CD4(+) cell counts < 200 cells/μL in 37.0%, whereas subjects with minor and moderate SIAs in the basal ganglia had CD4(+) cell counts < 200 cells/μL in 78.3% and 80.0%, respectively (P < .005). The percentage of subjects with CD4(+) cell counts < 200 cells/μL was 85.7% when there were progressive periventricular SIA changes and 45.5% when periventricular SIA changes were stable in follow-up (P < .05). The presence and progression of cerebral SIAs on T2-weighted magnetic resonance images reflecting cerebral infection with human immunodeficiency virus are significantly related to impaired immune state as measured by CD4(+) cell count. Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved.

The potential application of social impact assessment in integrated coastal zone management

NARCIS (Netherlands)

Vanclay, Frank

2012-01-01

Integrated coastal zone management (ICZM) would be significantly enhanced if there was greater connection to the field of social impact assessment (SIA). SIA is the process of managing the social issues of planned interventions (projects, policies, plans, and programs). SIA can also be used to

Social impact assessments: Developing a consolidated conceptual framework

Energy Technology Data Exchange (ETDEWEB)

Arce-Gomez, Antonio, E-mail: aarcegomez@swin.edu.au; Donovan, Jerome D., E-mail: jdonovan@swin.edu.au; Bedggood, Rowan E., E-mail: rbedggood@swin.edu.au

2015-01-15

Social Impact Assessments (SIAs) have played an increasingly important role in the conduct of planned interventions, providing proponents the capacity to assess and manage the social consequences of their activities. Whilst the SIA field has experienced significant conceptual and practical development over the last decade, efforts at consolidating this within one framework have been limited. In this paper, we incorporate this new knowledge by redeveloping and thus updating the SIA procedural framework developed by Interorganizational Committee on Guidelines and Principles for Social Impact Assessment. In doing so, this updated procedural framework has attempted to incorporate current ‘best practice’ that focuses on participatory approaches to undertaking an SIA. This involved making adaptions to two steps, expansions to five steps, integration of a stronger participatory approach to six steps, and the development of a new step, Management and Evaluation reflecting moves towards ex-post use of SIA processes. It is hoped that this consolidation of the literature of a decade's worth of key findings in SIA research will lead to further efforts towards a meta-evaluation of SIA literature and a platform from which newer developments may be further investigated.

Social impact assessments: Developing a consolidated conceptual framework

International Nuclear Information System (INIS)

Arce-Gomez, Antonio; Donovan, Jerome D.; Bedggood, Rowan E.

2015-01-01

Social Impact Assessments (SIAs) have played an increasingly important role in the conduct of planned interventions, providing proponents the capacity to assess and manage the social consequences of their activities. Whilst the SIA field has experienced significant conceptual and practical development over the last decade, efforts at consolidating this within one framework have been limited. In this paper, we incorporate this new knowledge by redeveloping and thus updating the SIA procedural framework developed by Interorganizational Committee on Guidelines and Principles for Social Impact Assessment. In doing so, this updated procedural framework has attempted to incorporate current ‘best practice’ that focuses on participatory approaches to undertaking an SIA. This involved making adaptions to two steps, expansions to five steps, integration of a stronger participatory approach to six steps, and the development of a new step, Management and Evaluation reflecting moves towards ex-post use of SIA processes. It is hoped that this consolidation of the literature of a decade's worth of key findings in SIA research will lead to further efforts towards a meta-evaluation of SIA literature and a platform from which newer developments may be further investigated

Social Impact Assessment: The lesser sibling in the South African EIA process?

Energy Technology Data Exchange (ETDEWEB)

Hildebrandt, L., E-mail: Leandri.hildebrandt@nwu.ac.za [African Centre for Disaster Studies, Research Focus Area: Social Transformation, North-West University, Private Bag X6001, Potchefstroom, 2520 (South Africa); Sandham, L.A., E-mail: luke.sandham@nwu.ac.za [Environmental Assessment Research Group, School of Geo and Spatial Sciences, North-West University, Private Bag X6001, Potchefstroom, 2520 (South Africa)

2014-09-15

Social Impact Assessment has developed as an integral but neglected component of EIA in South Africa since it became mandatory in 1997, and has therefore been referred to as the “orphan” or “lesser sibling” of EIA, as has SIA in the UK and the US. The aim of this paper is to test this claim by reviewing the quality of a sample of SIA reports, and also to establish whether there has been any improvement in quality following the introduction of revised EIA regulations in 2006. The results confirm that SIA can be called “the lesser sibling” due to the weak grades achieved in the quality review, but also reveal that there has been a slight and consistent improvement in quality, most likely driven by best practice considerations in the absence of prescriptive regulations for SIA. Suggestions and recommendations for addressing observed weakness in SIA performance are advanced. - Highlights: • The quality of a sample of SIA reports was evaluated using a review package. • SIA reports received mostly weak grades. • Limited improvement observed from first to second regulatory regime. • Improvements most likely due to best practice considerations.

Social Impact Assessment: The lesser sibling in the South African EIA process?

International Nuclear Information System (INIS)

Hildebrandt, L.; Sandham, L.A.

2014-01-01

Social Impact Assessment has developed as an integral but neglected component of EIA in South Africa since it became mandatory in 1997, and has therefore been referred to as the “orphan” or “lesser sibling” of EIA, as has SIA in the UK and the US. The aim of this paper is to test this claim by reviewing the quality of a sample of SIA reports, and also to establish whether there has been any improvement in quality following the introduction of revised EIA regulations in 2006. The results confirm that SIA can be called “the lesser sibling” due to the weak grades achieved in the quality review, but also reveal that there has been a slight and consistent improvement in quality, most likely driven by best practice considerations in the absence of prescriptive regulations for SIA. Suggestions and recommendations for addressing observed weakness in SIA performance are advanced. - Highlights: • The quality of a sample of SIA reports was evaluated using a review package. • SIA reports received mostly weak grades. • Limited improvement observed from first to second regulatory regime. • Improvements most likely due to best practice considerations

Displacement cascades and defect annealing in tungsten, Part III: The sensitivity of cascade annealing in tungsten to the values of kinetic parameters

Energy Technology Data Exchange (ETDEWEB)

Nandipati, Giridhar, E-mail: giridhar.nandipati@pnnl.gov [Pacific Northwest National Laboratory, Richland, WA (United States); Setyawan, Wahyu; Heinisch, Howard L. [Pacific Northwest National Laboratory, Richland, WA (United States); Roche, Kenneth J. [Pacific Northwest National Laboratory, Richland, WA (United States); Department of Physics, University of Washington, Seattle, WA 98195 (United States); Kurtz, Richard J. [Pacific Northwest National Laboratory, Richland, WA (United States); Wirth, Brian D. [University of Tennessee, Knoxville, TN (United States)

2015-07-15

A study has been performed using object kinetic Monte Carlo (OKMC) simulations to investigate various aspects of cascade aging in bulk tungsten (W) and to determine its sensitivity to the kinetic parameters. The primary focus is on how the kinetic parameters affect the intracascade recombination of defects. Results indicate that, due to the disparate mobilities of SIA and vacancy clusters, annealing is dominated by SIA migration even at 2050 K. It was found that for 100 keV cascades initiated at 300 K, recombination is dominated by the annihilation of large defect clusters, while for all the other primary knock-on atom (PKA) energies and temperatures, recombination is primarily due to the migration and rotation of small SIA clusters, while the large SIA clusters escape the simulation cell. The annealing efficiency exhibits an inverse U-shaped curve behavior with increasing temperature, especially at large PKA energies, caused by the asymmetry in SIA and vacancy clustering assisted by the large differences in their mobilities. This behavior is unaffected by the dimensionality of SIA migration, and it persists over a broad range of relative mobilities of SIAs and vacancies.

Armin Karu muutus Eesti rikkaimaks / Lauri Matsulevitsh

Index Scriptorium Estoniae

Matsulevitsh, Lauri

2006-01-01

Olympic Casino aktsiaid oli müügis 1,124 miljardi krooni eest, märgiti neid aga 7,5 miljardi krooni eest. Diagrammid: Viimaste börsiletulijate aktsia hinna liikumine kroonides esimesel kümnel päeval; Olympic tõi juurde uusi investoreid; Uute väärtpaberikontode arv; Aktsiaid märkinud jaeinvestorite arv viimastel IPOdel. Kommenteerivad Rainer Jürgenson, Peeter Koppel, Riho Talumaa ja Rainer Änilane

Villa Draiver / Mihkel Karu ; kommenteerinud Terje Truumaa

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2009-01-01

Villa Draiver (160 m2) Kuressaares Kotkapoja tänaval. Arhitekt ja sisearhitekt Terje Truumaa. Ehitaja: AS Kuressaare Ehitus. Valmis: 2008. Valdavas osas laia püstise helebeeži laudisega kaetud monoliitbetoonist hoone on mõeldud väljaüürimiseks golfihuvilistele

Krokodill sõi karu mett / Eero Kangor

Index Scriptorium Estoniae

Kangor, Eero, 1982-

2007-01-01

Tartu Ülikooli, Tartu Kõrgema Kunstikooli ja Tartu Kunstikooli õpilaste näitusest Tartu Kunstimuuseumis, kuraator Liisa Kaljula. Pikemalt Ronald Baumanni, Helen Kikkase, Margit Lõhmuse maalidest, Jana Huuli skulptuurist

Uut moodi Teine maailmasõda / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2009-01-01

Teise maailmasõja 70. aastapäevaks valminud kuueosalise doksarja "Apokalüpsis: WWII", (National Geographic, režissöör Isabelle Clarke, stsenaristid Henri de Turenne ja Daniel Costelle) filmimispaikades

Arhitektuuriuudiseid laiast maailmast - piiratud ruum / Mihkel Karu

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2006-01-01

Laevmaja Hollandis Muggenbeet'is (arhitekt Arnoud Olie, 2004-2005), noore pere korter Pariisis (arhitektid Nicola ja Adelaide Marchi, 2005), loft house Nagoyas (Shinichi Ogawa & Associates, 2005), eksperimentaalne elamu Lucky Drops Tokyos (Atelire Tekuto + Masahiro Ikeda CO., LMT., 2005), galeriikorter Cafe Au Lit Pariisis (arhitektid Didier Fuzia Faustino, Pascal Mazoyer, Bureau des Mesarchitectures, 2005), Studio D Tokyos (Hiroyuki Arima + Urban Fourth, 2005)

Lorena reeglid / Lorena Rojas ; interv. Kaisa Karu

Index Scriptorium Estoniae

Rojas, Lorena

2007-01-01

Mehhiko telenovelade staar, kes mängib ka sel hooajal TV3s jooksvas seriaalis "Teine võimalus" ("El cuerpo del deseo"), valiti ajak. People poolt 2006.a. maailma 100 ilusama naise hulka. Sama : Teleleht nr. 3, lk. 38 : ill

Juhmus ei tunne mingeid maakonnapiire / Kadri Karu

Index Scriptorium Estoniae

Karu, Kadri

2006-01-01

Papa Kreutzwaldi Õueteatris Lauluisa muuseumi õuel juulis etendunud Tartu Ülikooli Viljandi Kultuuriakadeemia kuuenda lennu teatritudengite lusti- ja laulumäng "Kilplased" F. R. Kreutzwaldi juttude ainetel, lavastaja Katri Aaslav-Tepandi. Kaheksa näitlejatudengit räägivad Kilplastest ja Rändteatri teekonnast

Puitu tahutud mõte : keskaegsed raepingid = Ideas Carved in Wood : Medieval Magistrates' Benches / Merike Koppel

Index Scriptorium Estoniae

Koppel, Merike

2004-01-01

Säilinud on ühe raepingi nikerdatud seljatugi ja käetugede otsalauad (14. saj. 2. pool), teise raepingi Simsoni võitlust lõviga ning Tristani ja Isolde armastuslugu kujutavad külgleenid (14. saj.), kolmanda pingi reljeefidega pingiküljed (Taaveti võitlus Koljatiga, karu ja lõvi ning Simson ja Delila, Aristoteles ja Phyllis) ja kaunistatud seljatugi (15. saj. algus) ning pingi juures olnud puuskulptuurid "Veronika rätt" (15. saj. keskpaik) ja Ristija Johannese pea (1460-ndad)

Arctic sea ice area changes in CMIP3 and CMIP5 climate models’ ensembles

Directory of Open Access Journals (Sweden)

V. A. Semenov

2017-01-01

Full Text Available The shrinking Arctic sea ice cover observed during the last decades is probably the clearest manifestation of ongoing climate change. While climate models in general reproduce the sea ice retreat in the Arctic during the 20th century and simulate further sea ice area loss during the 21st century in response to anthropogenic forcing, the models suffer from large biases and the results exhibit considerable spread. Here, we compare results from the two last generations of climate models, CMIP3 and CMIP5, with respect to total and regional Arctic sea ice change. Different characteristics of sea ice area (SIA in March and September have been analysed for the Entire Arctic, Central Arctic and Barents Sea. Further, the sensitivity of SIA to changes in Northern Hemisphere (NH temperature is investigated and dynamical links between SIA and some atmospheric variability modes are assessed.CMIP3 (SRES A1B and CMIP5 (RCP8.5 models not only simulate a coherent decline of the Arctic SIA but also depict consistent changes in the SIA seasonal cycle. The spatial patterns of SIC variability improve in CMIP5 ensemble, most noticeably in summer when compared to HadISST1 data. A better simulation of summer SIA in the Entire Arctic by CMIP5 models is accompanied by a slightly increased bias for winter season in comparison to CMIP3 ensemble. SIA in the Barents Sea is strongly overestimated by the majority of CMIP3 and CMIP5 models, and projected SIA changes are characterized by a high uncertainty. Both CMIP ensembles depict a significant link between the SIA and NH temperature changes indicating that a part of inter-ensemble SIA spread comes from different temperature sensitivity to anthropogenic forcing. The results suggest that, in general, a sensitivity of SIA to external forcing is enhanced in CMIP5 models. Arctic SIA interannual variability in the end of the 20th century is on average well simulated by both ensembles. To the end of the 21st century, September

The effects of one-dimensional migration of self-interstitial clusters on the formation of void lattices

DEFF Research Database (Denmark)

Heinisch, H.L.; Singh, B.N.

2002-01-01

under pure 3-D SIA migration, but they are extremely stable, relative to random arrays of voids, under 1-D SIA migration. Void lattices remain stable even under the condition of fairly frequent changes in the Burgers vectors of the 1-D migrating SIA clusters. Clusters with average 1-D path segments...

Toiduainetööstuse TOP aastal 2006 / Rivo Sarapik

Index Scriptorium Estoniae

Sarapik, Rivo, 1981-

2007-01-01

Ilmunud ka: Delovõje Vedomosti : Promõshlennost 17. okt. lk. 12-13. Edukamad toiduainetööstuse tootjad 2006. aastal. Vt. samas: Toiduainetööstuse üld- ja finantsandmed; Käibe TOP 5; Käibe kasvu TOP 5; Kasumi TOP 5; Kasumi kasvu TOP 5; Rentaabluse TOP 5; Omakapitali tootlikkuse TOP 5; Ketlin Priilinn:Võru Juust tipus emafirma abiga. Kommenteerib Tiia Karu. Diagramm; AS Tere tõuseb raske töö toel. Kommenteerib Aivar Häelm. Diagramm; Maag ajab jonnakusega oma asja. Diagramm

Kas usud seda? / Loore Ehrlich ; kommenteerinud Remo Savisaar

Index Scriptorium Estoniae

Ehrlich, Loore

2013-01-01

Müüdid: Talvituvad herilased kaitsevad pesa raevukalt; Karu tõuseb enne ründamist tagajalgadele; Kõik ämblikud on ohtlikult mürgised; Puuk kukutab end puude-põõsaste okstelt inimesele; Kõrvahark ronib kõrva ja sealt edasi ajju; Rästik jälitab inimest eesmärgiga rünnata; Nahkhiir on verdihkav vampiir; Ilves ründab inimest puuvõrast turja karates; Näljased hundid murravad inimesi; Sosnovski karuputk kõrvetab; Seen mis ussitab on söögi seen

Astrofisica delle alte energie

CERN Document Server

Vietri, Mario

2006-01-01

L'insegnamento dell'astrofisica moderna richiede conoscenze di base di svariate discipline, oltre ad alcuni modelli fondamentali. Lo scopo di questo libro è di presentare sia le une che gli altri in maniera possibilmente esaustiva, e di essere dunque utilizzabile sia come prima introduzione alle problematiche astrofisiche, sia come testo di riferimento ulteriore per giovani studiosi.

The actions of the social insurance agency regarding long-term sickness absentees before and after a medical assessment--a study of 384 case files.

Science.gov (United States)

Marklund, Staffan; Lundh, Göran; Gustafsson, Klas; Linder, Jürgen; Svedberg, Pia; Alexanderson, Kristina

2015-01-01

The purpose of this article is to investigate actions taken by the Social Insurance Agency (SIA) for long-term sickness absentees and possible associations of this with future sick leave or disability pension. For 384 long-term sickness absentees who had had a multidisciplinary medical assessment (MMA) during 2001-2006, three types of data were obtained: (1) case file information about SIA actions, (2) suggested rehabilitation measures from the MMA and (3) sickness absence and disability pension data. Most individuals had been subject to a range of actions by the SIA. Sixty percent had been invited to a coordination meeting, and half of those who assessed by the MMA for vocational rehabilitation were approved to get it by the SIA. Few SIA actions were associated with full or partial return to work. Although the studied individuals had been on sick leave for a long time, the number of SIA actions related to vocational rehabilitation was limited and came late in the sick-leave spell. The information from the MMA was often not used as a basis for further SIA action and seldom resulted in return to work. The positive MMA views on the potential of vocational rehabilitation were not met by SIA actions. Suggestions on vocational rehabilitation from a medical assessment was in many cases not used by the social insurance agency in relationship to long-term sickness absentees. Active rehabilitation measures by the social insurance agency were few and came late in the sickness absence process. Few of the activities taken by the social insurance agency enhanced return to work.

Avaliação de propriedades físicas em solos sob lavoura cafeeira nos municípios de Caratinga e Simonésia – MG

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Paulo do Nascimento

2009-12-01

Full Text Available Para avaliar algumas propriedades físicas do solo sob diferentes tratamentos (sistemas de plantio e de produção da cultura de café, nos municípios de Caratinga e Simonésia amostras compostas de Latossolos Vermelho Amarelo (LVA e Vermelho Amarelo Húmico (LVAH, amostras compostas de solo foram coletadas nas profundidades de 0 a 30 cm e de 30 a 60 cm. Os sistemas de manejo estudados foram: adensado convencional, tradicional convencional e adensado orgânico. Amostras de cada solo sob remanescente florestal serviram de testemunha. Os dados foram organizados segundo o delineamento experimental inteiramente casualizado. Análises de variâncias foram realizadas pelo teste F e as médias foram testadas pelo teste Tukey. Nos solos avaliados não houve aumento significativo da densidade do solo nos sistemas cultivados. Os agroecossistemas no LVAH, na profundidade 0 a 30 cm, elevaram sua microporosidade em relação aos solos originais. Os LVAH são mais propensos à percolação de nutrientes que o LVA, em função da maior porosidade total. Mais agregados de maior diâmetro no LVAH é atribuída à maior quantidade de matéria orgânica nesses solos. Os tratamentos orgânicos favoreceram a presença de agregados maiores no solo e melhoraram sua estabilidade estrutural. Os agroecossistemas modificaram as propriedades originais dos solos, sendo, ambientalmente sustentáveis.

Spectrophotometric intracutaneous analysis for differential diagnosis of pigmented skin lesions

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Е. V. Filonenko

2013-01-01

Full Text Available The non-invasive diagnosis of pigmented skin lesions by spectrophotometric intracutaneous analysis (SIA-scopy using device for dermatoscopy (SIAscope V by Astron Clinica, Ltd was approved in P.A.Herzen Moscow Cancer Research Institute. The method is based on analysis of light interaction with wavelength of 440–960 nm anf human skin, which is recorded by change of image on scan. The comparative analysis of SIA-scopy and histological data in 327 pigmented skin lesions in 147 patients showed, that SIA had high diagnostic efficiency for cutaneous melanoma: the sensitivity was 96%, specifity – 94%, diagnostic accuracy – 94%. For study of malignant potential of pigmented lesions by SIA-scopy the most informative capacity was obtained for assessment of melanin in papillary dermis, status of blood vessels and collagen fibres (SIA-scans 3, 4, 5.

Polysialic acid modification of the synaptic cell adhesion molecule SynCAM 1 in human embryonic stem cell-derived oligodendrocyte precursor cells

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Sebastian Werneburg

2015-05-01

Full Text Available Oligodendrocyte precursor cells (OPCs are the progenitors of myelinating oligodendrocytes in brain development and repair. Successful myelination depends on the control of adhesiveness during OPC migration and axon contact formation. The decoration of cell surface proteins with the glycan polysialic acid (polySia is a key regulatory element of OPC interactions during development and under pathological conditions. By far the major protein carrier of polySia is the neural cell adhesion molecule NCAM, but recently, polysialylation of the synaptic cell adhesion molecule SynCAM 1 has been detected in the developing mouse brain. In mice, polySia-SynCAM 1 is associated with cells expressing NG2, a marker of a heterogeneous precursor cell population, which is the primary source for oligodendrocytes in development and myelin repair but can also give rise to astrocytes and possibly neurons. It is not yet clear if polySia-SynCAM 1 is expressed by OPCs and its occurrence in humans is elusive. By generating uniform human embryonic stem cell-derived OPC cultures, we demonstrate that polySia is present on human OPCs but down-regulated during differentiation into myelin basic protein-positive oligodendrocytes. PolySia on NCAM resides on the isoforms NCAM-180 and NCAM-140, and SynCAM 1 is identified as a novel polySia acceptor in human OPCs.

BOOK REVIEWS / RECENSIONI

African Journals Online (AJOL)

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armi da fuoco, Campanella risponde: “È la poesia l'arma che colpisce a distanza” e questa, lui dice d'aver perfezionato come Dante. Dopo il convegno del 1990 su “Poesia e Filosofia”, il romanziere ha messo in rilievo la titanica figura del suo corregionale sia come filosofo, sia come teorico in “Poetica”, sia come autore di ...

Displacement cascades and defect annealing in tungsten, Part III: The sensitivity of cascade annealing in tungsten to the values of kinetic parameters

Energy Technology Data Exchange (ETDEWEB)

Nandipati, Giridhar; Setyawan, Wahyu; Heinisch, Howard L.; Roche, Kenneth J.; Kurtz, Richard J.; Wirth, Brian D.

2015-07-01

Object kinetic Monte Carlo (OKMC) simulations have been performed to investigate various aspects of cascade aging in bulk tungsten and to determine the sensitivity of the results to the kinetic parameters. The primary focus is on how the kinetic parameters affect the initial recombination of defects in the first few ns of a simulation. The simulations were carried out using the object kinetic Monte Carlo (OKMC) code KSOME (kinetic simulations of microstructure evolution), using a database of cascades obtained from results of molecular dynamics (MD) simulations at various primary knock-on atom (PKA) energies and directions at temperatures of 300, 1025 and 2050 K. The OKMC model was parameterized using defect migration barriers and binding energies from ab initio calculations. Results indicate that, due to the disparate mobilities of SIA and vacancy clusters in tungsten, annealing is dominated by SIA migration even at temperatures as high as 2050 K. For 100 keV cascades initiated at 300 K recombination is dominated by annihilation of large defect clusters. But for all other PKA energies and temperatures most of the recombination is due to the migration and rotation of small SIA clusters, while all the large SIA clusters escape the cubic simulation cell. The inverse U-shape behavior exhibited by the annealing efficiency as a function of temperature curve, especially for cascades of large PKA energies, is due to asymmetry in SIA and vacancy clustering assisted by the large difference in mobilities of SIAs and vacancies. This annealing behavior is unaffected by the dimensionality of SIA migration persists over a broad range of relative mobilities of SIAs and vacancies.

Analysis of labour risks in the Spanish industrial aerospace sector

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JUAN LAGUARDIA

Full Text Available ABSTRACT Labour risk prevention is an activity integrated within Safety and Hygiene at Work in Spain. In 2003, the Electronic Declaration for Accidents at Work, Delt@ (DELTA was introduced. The industrial aerospace sector is subject to various risks. Our objective is to analyse the Spanish Industrial Aerospace Sector (SIAS using the ACSOM methodology to assess its labour risks and to prioritise preventive actions. The SIAS and the Services Subsector (SS were created and the relevant accident rate data were obtained. The ACSOM method was applied through double contrast (deviation and translocation of the SIAS or SS risk polygon with the considered pattern, accidents from all sectors (ACSOM G or the SIAS. A list of risks was obtained, ordered by action phases. In the SIAS vs. ACSOM G analysis, radiation risks were the worst, followed by overstrains. Accidents caused by living beings were also significant in the SS vs. SIAE, which will be able to be used to improve Risk Prevention. Radiation is the most significant risk in the SIAS and the SS. Preventive actions will be primary and secondary. ACSOM has shown itself to be a valid tool for the analysis of labour risks.

Analysis of labour risks in the Spanish industrial aerospace sector.

Science.gov (United States)

Laguardia, Juan; Rubio, Emilio; Garcia, Ana; Garcia-Foncillas, Rafael

2016-01-01

Labour risk prevention is an activity integrated within Safety and Hygiene at Work in Spain. In 2003, the Electronic Declaration for Accidents at Work, Delt@ (DELTA) was introduced. The industrial aerospace sector is subject to various risks. Our objective is to analyse the Spanish Industrial Aerospace Sector (SIAS) using the ACSOM methodology to assess its labour risks and to prioritise preventive actions. The SIAS and the Services Subsector (SS) were created and the relevant accident rate data were obtained. The ACSOM method was applied through double contrast (deviation and translocation) of the SIAS or SS risk polygon with the considered pattern, accidents from all sectors (ACSOM G) or the SIAS. A list of risks was obtained, ordered by action phases. In the SIAS vs. ACSOM G analysis, radiation risks were the worst, followed by overstrains. Accidents caused by living beings were also significant in the SS vs. SIAE, which will be able to be used to improve Risk Prevention. Radiation is the most significant risk in the SIAS and the SS. Preventive actions will be primary and secondary. ACSOM has shown itself to be a valid tool for the analysis of labour risks.

Il libro di fisica

CERN Document Server

Asimov, Isaac

1986-01-01

Isaac Asimov, illustre studioso e brillante divulgatore scientifico, ma anche grandissimo scrittore di science fiction, ha costruito questa volta una vera e propria «biografia delle scienze fisiche». Il presente volume, che nel mondo anglosassone è diventato una «bibbia della fisica», ci introduce, in forma semplice ma rigorosa, ai segreti dei quasar e dei buchi neri, dei quark e degli acceleratori di particelle, dell'intelligenza artificiale e delle fonti di energia, sia essa quella «sporca» sia quella «pulita». Un vero, completo manuale, ma anche un «romanzo» affascinante sia per il profano sia per l'uomo di scienza.

Vana hea nõukogude kvaliteet / Jaak Kilmi

Index Scriptorium Estoniae

Kilmi, Jaak, 1973-

2002-01-01

SRÜ ja Baltimaade 11. filmifestivalil Anapas programmi "Avatud videoööd" koostaja muleid ja hinnanguid festivalilt. Parima meesnäitleja preemia sai Rain Simmul Nika osa eest Arvo Iho mängufilmis "Karu süda", žürii märkis ära Mark Soosaare 8-minutilise "La Paloma", "Avatud videoööde" peapreemia sai Mikk Ranna "Sääsk ja hobune". Festivali parimaks filmiks kuulutati Igor Minajevi "Kuumaastikud" ("Lunnõje poljanõ"), mille peaosatäitja Alissa Bogart sai parima naisnäitleja preemia

An MD simulation of interactions between self-interstitial atoms and edge dislocation in bcc transition metals

Energy Technology Data Exchange (ETDEWEB)

Kamiyama, H. (Aomori Public College, 153-4 Yamazaki, Goushi-zawa, Aomori 030-01 (Japan)); Rafii-Tabar, H. (Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980 (Japan)); Kawazoe, Y. (Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980 (Japan)); Matsui, H. (Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980 (Japan))

1994-09-01

According to our model on the mechanism of dislocation bias reduction based on the interaction of dumbbell self-interstitial atoms (SIAs) with dislocation, the bias is significantly different depending on the dumbbell configuration in the dislocation strain field. A large-scale molecular dynamics (MD) simulation is performed to reveal the stability and the mechanism of diffusion of dumbbell SIAs near the edge dislocation core in bcc iron. Most SIAs take the crowdion configuration parallel to the Burgers vector in the expansion side of the dislocation. Such crowdions are stable in the temperature range of this simulation, i.e. between 373 and 473 K, making one-dimensional random to-and-fro motion parallel to the dislocation Burgers vector staying at several atomic layers below'' the dislocation core. This means that the SIA does not approach the dislocation core. These results suggest that the stable configuration of SIAs is seriously affected by the dislocation resulting in a reduction of bias factor. ((orig.))

An MD simulation of interactions between self-interstitial atoms and edge dislocation in bcc transition metals

International Nuclear Information System (INIS)

Kamiyama, H.; Rafii-Tabar, H.; Kawazoe, Y.; Matsui, H.

1994-01-01

According to our model on the mechanism of dislocation bias reduction based on the interaction of dumbbell self-interstitial atoms (SIAs) with dislocation, the bias is significantly different depending on the dumbbell configuration in the dislocation strain field. A large-scale molecular dynamics (MD) simulation is performed to reveal the stability and the mechanism of diffusion of dumbbell SIAs near the edge dislocation core in bcc iron. Most SIAs take the crowdion configuration parallel to the Burgers vector in the expansion side of the dislocation. Such crowdions are stable in the temperature range of this simulation, i.e. between 373 and 473 K, making one-dimensional random to-and-fro motion parallel to the dislocation Burgers vector staying at several atomic layers ''below'' the dislocation core. This means that the SIA does not approach the dislocation core. These results suggest that the stable configuration of SIAs is seriously affected by the dislocation resulting in a reduction of bias factor. ((orig.))

Anamnésia e hipomnésia: Platão, primeiro pensador do proletariado

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Bernard Stiegler

2009-06-01

Full Text Available Este texto trata da exteriorização da memória, isto é, da técnica como perda do saber. O processo de exteriorização (mnemotecnologias se concretiza como história da gramatização, história técnica da memória, onde a memória hipomnésica relança a constituição de uma tensão de memória anamnésica. Como as questões filosóficas são questões de transindividuação, em termos de filosofia política, tratase de descrever e de criticar os processos concretos de transindividuação e pensar as hypomnémata digitais e as novas formas de otium que podem aparecer e fundar uma nova economia política da memória e do desejo.This text deals with the exteriorization of memory, that is, of technique as loss of knowledge. The process of exteriorization (mnemotechnology concretizes itself as history of grammatization, technical history of memory, in which hipomnesic memory reinstitutes the constitution of an anamnestic memory tension. Since the philosophical questions as transindividuation questions, in terms of political philosophy, it deals with describing and criticizing the concrete processes of transindividuation and thinking the digital hypomnémata and the new ways of otium that may appear and found a new political economy of memory and desire.

A ‘post-honeymoon’ measles epidemic in Burundi: mathematical model-based analysis and implications for vaccination timing

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Katelyn C. Corey

2016-09-01

Full Text Available Using a mathematical model with realistic demography, we analyze a large outbreak of measles in Muyinga sector in rural Burundi in 1988–1989. We generate simulated epidemic curves and age × time epidemic surfaces, which we qualitatively and quantitatively compare with the data. Our findings suggest that supplementary immunization activities (SIAs should be used in places where routine vaccination cannot keep up with the increasing numbers of susceptible individuals resulting from population growth or from logistical problems such as cold chain maintenance. We use the model to characterize the relationship between SIA frequency and SIA age range necessary to suppress measles outbreaks. If SIAs are less frequent, they must expand their target age range.

Social interaction anxiety and personality traits predicting engagement in health risk sexual behaviors.

Science.gov (United States)

Rahm-Knigge, Ryan L; Prince, Mark A; Conner, Bradley T

2018-06-01

Individuals with social interaction anxiety, a facet of social anxiety disorder, withdraw from or avoid social encounters and generally avoid risks. However, a subset engages in health risk sexual behavior (HRSB). Because sensation seeking, emotion dysregulation, and impulsivity predict engagement in HRSB among adolescents and young adults, the present study hypothesized that latent classes of social interaction anxiety and these personality traits would differentially predict likelihood of engagement in HRSB. Finite mixture modeling was used to discern four classes: two low social interaction anxiety classes distinguished by facets of emotion dysregulation, positive urgency, and negative urgency (Low SIAS High Urgency and Low SIAS Low Urgency) and two high social interaction anxiety classes distinguished by positive urgency, negative urgency, risk seeking, and facets of emotion dysregulation (High SIAS High Urgency and High SIAS Low Urgency). HRSB were entered into the model as auxiliary distal outcomes. Of importance to this study were findings that the High SIAS High Urgency class was more likely to engage in most identified HRSB than the High SIAS Low Urgency class. This study extends previous findings on the heterogeneity of social interaction anxiety by identifying the effects of social interaction anxiety and personality on engagement in HRSB. Copyright © 2018 Elsevier Ltd. All rights reserved.

Pendekatan Conjoint Analysis untuk Mengukur Tingkat Preferensi Mahasiswa terhadap Layanan Sistem Informasi Akademik di UIN Yogyakarta

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Epha Diana Supandi

2012-04-01

Full Text Available Information Technology (IT represent one of main indicator to support the academic atmosphere at the university. Therefore UIN Sunan Kalijaga (Suka Yogyakarta has owned sistem information technology and it is called Academic Information System (SIA. UIN Suka shall has knowledge preference and perception of consumer to the service, which is like what required by consumer. By using Conjoint Analysis method would have been obtained combination from level-level factor (stimuly took a fancy by consumer according to value of highest utility from every level factor.  The objective of this research is to measure preference level of consumers (students to the SIA services in UIN Suka used Conjoint Analysis method. The result shows that the most important factor in using SIA service is the benefit (importance value is 66,623%, the second important factor is accesibility of SIA ( importance value is 19,227% and the last important is ability of staff  (importance value is 14,15%. According to value of utility estimate, it shows that consumers like to use SIA for key in courses (utility estimate is 2,104, online service (utility estimate is 0,577 and SIA staff who are very friendly when they were servicing the students (utility estimate is 0,210.

Effects of polio eradication activities on routine immunization: lessons from the 2013 outbreak response in Somali region of Ethiopia.

Science.gov (United States)

Tafesse, Belete; Tekle, Ephrem; Wondwossen, Liya; Bogale, Mengistu; Fiona, Braka; Nsubuga, Peter; Tomas, Karengera; Kassahun, Aron; Kathleen, Gallagher; Teka, Aschalew

2017-01-01

Ethiopia experienced several WPV importations with a total of 10 WPV1 cases confirmed during the 2013 outbreak alone before it is closed in 2015. We evaluated supplemental immunization activities (SIAs), including lessons learned for their effect on the routine immunization program during the 2013 polio outbreak in Somali regional state. We used descriptive study to review documents and analyse routine health information system reports from the polio outbreak affected Somali regional state. All data and technical reports of the 15 rounds of polio SIAs from June 2013 through June 2015 and routine immunization coverages for DPT-Hib-HepB 3 and measles were observed. More than 93% of the SIAs were having administrative coverage above 95%. The trend of routine immunization for the two antigens, over the five years (2011 through 2015) did not show a consistent pattern against the number of SIAs. Documentations showed qualitative positive impacts of the SIAs strengthening the routine immunization during all courses of the campaigns. The quantitative impact of polio SIAs on routine immunization remained not so impressive in this study. Clear planning, data consistencies and completeness issues need to be cleared for the impact assessment in quantitative terms, in polio legacy planning as well as for the introduction of injectable polio vaccine through the routine immunization.

Stable isotopes and elasmobranchs: tissue types, methods, applications and assumptions.

Science.gov (United States)

Hussey, N E; MacNeil, M A; Olin, J A; McMeans, B C; Kinney, M J; Chapman, D D; Fisk, A T

2012-04-01

Stable-isotope analysis (SIA) can act as a powerful ecological tracer with which to examine diet, trophic position and movement, as well as more complex questions pertaining to community dynamics and feeding strategies or behaviour among aquatic organisms. With major advances in the understanding of the methodological approaches and assumptions of SIA through dedicated experimental work in the broader literature coupled with the inherent difficulty of studying typically large, highly mobile marine predators, SIA is increasingly being used to investigate the ecology of elasmobranchs (sharks, skates and rays). Here, the current state of SIA in elasmobranchs is reviewed, focusing on available tissues for analysis, methodological issues relating to the effects of lipid extraction and urea, the experimental dynamics of isotopic incorporation, diet-tissue discrimination factors, estimating trophic position, diet and mixing models and individual specialization and niche-width analyses. These areas are discussed in terms of assumptions made when applying SIA to the study of elasmobranch ecology and the requirement that investigators standardize analytical approaches. Recommendations are made for future SIA experimental work that would improve understanding of stable-isotope dynamics and advance their application in the study of sharks, skates and rays. © 2012 The Authors. Journal of Fish Biology © 2012 The Fisheries Society of the British Isles.

Kuidas turundatakse ülikooli Ameerikas? / Kaisa-Triin Karu

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Karu, Kaisa-Triin

2015-01-01

Artikli autor veetis aasta vahetusüliõpilasena Emporia State Universitys, õppides turundust ja töötades ülikooli turundusosakonnas. Kuidas Epmoria State end turundab, vestlusest turundusdirektori Umair Abbasiga

Naised mõrvarite jälil / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2010-01-01

Kanal 2 ekraanil kaks naispeaosalistega krimisarja : uurija Lilly Rush (Kathryn Morris) sarjas "Jahtunud jälg" (USA, 2003-... ) ja Brenda Leigh Johnson (Kyra Sedgwick) seriaalis "Vahelevõtja" (USA, 2005-... )

Sweeney Todd : Fleet Streeti deemonlik habemeajaja / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2008-01-01

Lühiarvustus õudusmuusikalile "Sweeney Todd : Fleet Streeti deemonlik habemeajaja" (Stephen Sondheimi muusikali alusel), režissöör Tim Burton : peaosades Johnny Depp, Helena Bonham Carter : Ameerika Ühendriigid - Suurbritannia 2007

Il fuoco della fusione termonucleare controllata

CERN Document Server

Caldirola, Piero; Sindoni, Elio

1984-01-01

Per realizzare la fusione termonucleare controllata, cioè catturare e dominare il fuoco che accende gli astri, e ottenere così una nuova fonte di energia praticamente illimitata e a basso costo, si richiede uno sforzo collettivo e unitario globale: non esiste infatti nazione al mondo che sia in grado, singolarmente presa, di affrontare il problema, sia per le risorse finanziarie necessarie all'impresa sia per il numero dei ricercatori che dovranno dedicarvisi.

Internal friction measurements of Mo after low-temperature proton irradiation

International Nuclear Information System (INIS)

Tanimoto, H.; Mizubayashi, H.; Masuda, R.; Okuda, S.; Tagishi, Y.

1992-01-01

Internal friction measurements are performed in Mo after 20 MeV proton irradiation in order to clarify the behavior of self-interstitial atoms (SIA's) in Mo. In the low dose range, strong dislocation pinning suggesting the free migration of defects is observed at about 40 K and weak pinning at about 25 K. The features are very similar to those reported after neutron irradiation except that the 25 K pinning is much smaller after proton irradiation. The result suggests that the migration of free SIA's is responsible for the 40 K pinning and that of SIA-defect clusters, probably di-SIA's, formed during irradiation for the 25 K pinning. In the high dose range, the relaxation peaks are observed at about 13 and 41 K, where the close similarities are found between the present peaks and the corresponding peaks reported after neutron irradiation except that the peak height of the 41 K peak per unit concentration of Frenkel pairs (FP) tends to increase strongly with decreasing dose here. The latter fact suggests the strong interaction between SIA's. Then the smallness of the 41 K peak reported after electron irradiation with very high dose could be explained by an increased interaction between SIA's, but not by the two-dimensional migration of SIA's as proposed by Jacques and Robrock. Deformation given prior to irradiation causes a drastic decrease in the modulus defects associated with FP's (so-called bulk effect) and in the 13 K peak height. After neutron irradiation, no such effect of deformation was reported. A possible origin for this difference is discussed. (orig.)

Expression of polysialylated neural cell adhesion molecules on adult stem cells after neuronal differentiation of inner ear spiral ganglion neurons

International Nuclear Information System (INIS)

Park, Kyoung Ho; Yeo, Sang Won; Troy, Frederic A.

2014-01-01

Highlights: • PolySia expressed on neurons primarily during early stages of neuronal development. • PolySia–NCAM is expressed on neural stem cells from adult guinea pig spiral ganglion. • PolySia is a biomarker that modulates neuronal differentiation in inner ear stem cells. - Abstract: During brain development, polysialylated (polySia) neural cell adhesion molecules (polySia–NCAMs) modulate cell–cell adhesive interactions involved in synaptogenesis, neural plasticity, myelination, and neural stem cell (NSC) proliferation and differentiation. Our findings show that polySia–NCAM is expressed on NSC isolated from adult guinea pig spiral ganglion (GPSG), and in neurons and Schwann cells after differentiation of the NSC with epidermal, glia, fibroblast growth factors (GFs) and neurotrophins. These differentiated cells were immunoreactive with mAb’s to polySia, NCAM, β-III tubulin, nestin, S-100 and stained with BrdU. NSC could regenerate and be differentiated into neurons and Schwann cells. We conclude: (1) polySia is expressed on NSC isolated from adult GPSG and on neurons and Schwann cells differentiated from these NSC; (2) polySia is expressed on neurons primarily during the early stage of neuronal development and is expressed on Schwann cells at points of cell–cell contact; (3) polySia is a functional biomarker that modulates neuronal differentiation in inner ear stem cells. These new findings suggest that replacement of defective cells in the inner ear of hearing impaired patients using adult spiral ganglion neurons may offer potential hope to improve the quality of life for patients with auditory dysfunction and impaired hearing disorders

Expression of polysialylated neural cell adhesion molecules on adult stem cells after neuronal differentiation of inner ear spiral ganglion neurons

Energy Technology Data Exchange (ETDEWEB)

Park, Kyoung Ho [Department of Otolaryngology Head and Neck Surgery, College of Medicine, Catholic University, Seoul (Korea, Republic of); Yeo, Sang Won, E-mail: swyeo@catholic.ac.kr [Department of Otolaryngology Head and Neck Surgery, College of Medicine, Catholic University, Seoul (Korea, Republic of); Troy, Frederic A., E-mail: fatroy@ucdavis.edu [Department of Biochemistry and Molecular Medicine, University of California, School of Medicine, Davis, CA 95616 (United States); Xiamen University, School of Medicine, Xiamen City (China)

2014-10-17

Highlights: • PolySia expressed on neurons primarily during early stages of neuronal development. • PolySia–NCAM is expressed on neural stem cells from adult guinea pig spiral ganglion. • PolySia is a biomarker that modulates neuronal differentiation in inner ear stem cells. - Abstract: During brain development, polysialylated (polySia) neural cell adhesion molecules (polySia–NCAMs) modulate cell–cell adhesive interactions involved in synaptogenesis, neural plasticity, myelination, and neural stem cell (NSC) proliferation and differentiation. Our findings show that polySia–NCAM is expressed on NSC isolated from adult guinea pig spiral ganglion (GPSG), and in neurons and Schwann cells after differentiation of the NSC with epidermal, glia, fibroblast growth factors (GFs) and neurotrophins. These differentiated cells were immunoreactive with mAb’s to polySia, NCAM, β-III tubulin, nestin, S-100 and stained with BrdU. NSC could regenerate and be differentiated into neurons and Schwann cells. We conclude: (1) polySia is expressed on NSC isolated from adult GPSG and on neurons and Schwann cells differentiated from these NSC; (2) polySia is expressed on neurons primarily during the early stage of neuronal development and is expressed on Schwann cells at points of cell–cell contact; (3) polySia is a functional biomarker that modulates neuronal differentiation in inner ear stem cells. These new findings suggest that replacement of defective cells in the inner ear of hearing impaired patients using adult spiral ganglion neurons may offer potential hope to improve the quality of life for patients with auditory dysfunction and impaired hearing disorders.

Migration mechanisms of self-interstitial atoms and their clusters in Fe-Cr alloys

International Nuclear Information System (INIS)

Terentyev, D.; Malerba, L.

2006-06-01

The mobility of self-interstitial atoms (SIAs) and their clusters in pure iron and iron-chromium alloys was studied by atomic scale modelling techniques. Molecular dynamics (MD) was used to simulate thermally activated motion, i.e. diffusion, and its mechanisms whereas molecular statics was used to estimate energies of interactions of SIA and SIA clusters with Cr-impurities. It is shown that the presence of Cr atoms reduces the diffusivity of SIAs and their clusters in a non monotonic way with increasing Cr concentration. The main reason for this reduction is the presence of a long-range attractive interaction between self-interstitials in the crowdion configuration and Cr atoms. The migration mechanisms behind this effect are discussed relying on the results obtained from the MD simulations. (author)

Review of Calculations on Point Defect Properties in Delta-Pu

Energy Technology Data Exchange (ETDEWEB)

Allen, P. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wolfer, W. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2015-09-08

The results of theoretical predictions of properties for vacancies and self-interstitial atoms (SIA) in δ-Pu are presented and reviewed. Three methods have been used for these predictions, namely the modified embedded atom method (MEAM), density functional theory (DFT) with and without spin polarization, and continuum mechanics (CM) models adapted to plutonium. The properties considered are formation and migration energies, and relaxation volumes of vacancies and SIA. Predicted values vary considerably. Nevertheless, all three methods predict that the activation energy for self-diffusion by vacancies is of similar magnitude as the SIA formation energy. Furthermore, the absolute magnitudes of relaxation volumes for vacancies and SIA are also similar, indicating that there exist no large bias for radiation-induced void swelling.

Review of Calculations on Point Defect Properties in Delta-Pu

International Nuclear Information System (INIS)

Allen, P. G.; Wolfer, W. G.

2015-01-01

The results of theoretical predictions of properties for vacancies and self-interstitial atoms (SIA) in δ-Pu are presented and reviewed. Three methods have been used for these predictions, namely the modified embedded atom method (MEAM), density functional theory (DFT) with and without spin polarization, and continuum mechanics (CM) models adapted to plutonium. The properties considered are formation and migration energies, and relaxation volumes of vacancies and SIA. Predicted values vary considerably. Nevertheless, all three methods predict that the activation energy for self-diffusion by vacancies is of similar magnitude as the SIA formation energy. Furthermore, the absolute magnitudes of relaxation volumes for vacancies and SIA are also similar, indicating that there exist no large bias for radiation-induced void swelling.

Doppler Ultrasonography in Suspected Subclavian Artery Obstruction and in Patient Monitoring after Subclavian Stenting

International Nuclear Information System (INIS)

Kablak-Ziembicka, Anna; Przewlocki, Tadeusz; Pieniazek, Piotr; Musialek, Piotr; Kozanecki, Artur; Stopa, Ireneusz; Zalewski, Jaroslaw; Tracz, Wieslawa

2007-01-01

Purpose. Subclavian or innominate artery (SIA) stenosis affects up to 5% of patients referred to coronary bypass grafting; it is symptomatic in less than half of these. This study aimed to assess the Doppler ultrasonography (DU) findings in SIA obstruction and patients' follow-up after percutaneous angioplasty (PTA). Methods. The study enrolled 118 patients (68 men, 50 women), aged 61.3 ± 8.7 years, with suspected SIA obstruction, in whom peak systolic velocity (PSV) in the SIA and subclavian steal grade were assessed on DU and verified by quantitative angiography (QA). Serial follow-up DU was performed in patients treated with PTA. Results. Grade I-III of subclavian steal from the vertebral artery (VA) was found in 89.8% of patients. In the remaining 10.2% only a PSV increase in the SIA was observed. QA confirmed the presence of SIA obstruction in all patients (stenosis grade: 80.9 ± 17.3%). In patients with one-sided SIA obstruction, the ultrasonographic steal grade correlated with the QA stenosis grade (p < 0.001, r = 0.648). Lack of subclavian steal was noted in the case of distal subclavian stenosis, VA obstruction, VA originating from the aortic arch, and bilateral SIA obstruction. Successful PTA was performed in 77 of 83 patients referred to that procedure. PSV was reduced from 4.4 ± 1.2 (2.2-6.5) m/sec to 1.34 ± 0.51 (0.5-2.5) m/sec and flow in the VA was normalized. During the mean follow-up time of 24.7 ± 15.6 months, there was a gradual increase in the in-stent PSV as well as gradual VA flow alterations, resulting in symptom recurrence. More than a twofold PSV increase, compared with the post-PTA values, was an indicator of restenosis in 11 of 12 patients. Conclusions. Careful DU evaluation enables the recognition of SIA obstruction in all patients. Ninety percent of them have subclavian steal correlating with the stenosis grade. Restenosis can be reliably detected with DU based on in-stent PSV and VA flow alterations

Development of a simple and efficient method for assaying cytidine monophosphate sialic acid synthetase activity using an enzymatic reduced nicotinamide adenine dinucleotide/oxidized nicotinamide adenine dinucleotide converting system.

Science.gov (United States)

Fujita, Akiko; Sato, Chihiro; Münster-Kühnel, Anja-K; Gerardy-Schahn, Rita; Kitajima, Ken

2005-02-01

A new reliable method to assay the activity of cytidine monophosphate sialic acid (CMP-Sia) synthetase (CSS) has been developed. The activation of sialic acids (Sia) to CMP-Sia is a prerequisite for the de novo synthesis of sialoglycoconjugates. In vertebrates, CSS has been cloned from human, mouse, and rainbow trout, and the crystal structure has been resolved for the mouse enzyme. The mouse and rainbow trout enzyme have been compared with respect to substrate specificity, demonstrating that the mouse enzyme exhibits a pronounced specificity for N-acetylneuraminic acid (Neu5Ac), while the rainbow trout CSS is equally active with either of three Sia species, Neu5Ac, N-glycolylneuraminic acid (Neu5Gc), and deaminoneuraminic acid (KDN). However, molecular details that explain the pronounced substrate specificities are unknown. Understanding the catalytic mechanisms of these enzymes is of major importance, since CSSs play crucial roles in cellular sialylation patterns and thus are potential drug targets in a number of pathophysiological situations. The availability of the cDNAs and the obtained structural data enable rational approaches; however, these efforts are limited by the lack of a reliable high-throughput assay system. Here we describe a new assay system that allows product quantification in a reduced nicotinamide adenine dinucleotide (NADH)-dependent color reaction. The activation reaction catalyzed by CSS, CTP+Sia-->CMP-Sia+pyrophosphate, was evaluated by a consumption of Sia, which corresponds to that of NADH on the following two successive reactions: (i) Sia-->pyruvate+ManNAc (or Man), catalyzed by a sialic acid lyase (SAL), and (ii) pyruvate+NADH-->lactate+oxidized nicotinamide adenine dinucleotide (NAD+), catalyzed by a lactate dehydrogenase (LDH). Consumption of NADH can be photometrically monitored on a microtiter plate reader for a number of test samples at the same time. Furthermore, based on the quantification of CSS used in the SAL/LDH assay

The Dutch Social Interaction Anxiety Scale and the Social Phobia Scale: Reliability, Validity, and Clinical Utility

OpenAIRE

de Beurs, Edwin; Tielen, Deirdre; Wollmann, Lisa

2014-01-01

The social interaction anxiety scale (SIAS) and the social phobia scale (SPS) assess anxiety in social interactions and fear of scrutiny by others. This study examines the psychometric properties of the Dutch versions of the SIAS and SPS using data from a large group of patients with social phobia and a community-based sample. Confirmatory factor analysis revealed that the SIAS is unidimensional, whereas the SPS is comprised of three subscales. The internal consistency of the scales and subsc...

Engineered antibodies for monitoring of polynuclear aromatic hydrocarbons

International Nuclear Information System (INIS)

Karu, A.E.; Li, Q.X.; Roberts, V.A.

1998-01-01

'The long-term goal of this project is to develop antibodies and antibody-based methods for detection and recovery of polynuclear aromatic hydrocarbons (PAHs) and PAH adducts that are potential biomarkers in environmental and biological samples. The inherent cross-reactivity will be exploited by pattern recognition methods. Dr. Karu''s laboratory uses new haptens representing key PAHs to derive recombinant Fab (rFab) and single-chain Fv (scFv) antibodies from hybridoma lines and combinatorial phage display libraries. Computational models of the haptens and combining sites made by Dr. Roberts''s group are used to guide antibody engineering by mutagenesis. Dr. Li''s laboratory develops enzyme immunoassays (EIAs), sensors, and immunoaffinity methods that make use of the novel haptens and antibodies for practical analytical applications in support of DOE''s mission. This report summarizes work completed in one and one-half years of a 3-year project, with close collaboration between the three research groups. Dr. Alexander Karu''s laboratory: the authors proceeded with the two strategies described in the original proposal. Site-directed mutagenesis was used to correct differences in the rFab N-terminal amino acids that were introduced by the degenerate PCR primers used for gene amplification. The binding constants of the rFabs with the corrected sequences will be compared with those of the parent MAbs, and should be very similar. The 4D5 and 10C10 heavy and light chain sequences are being moved to the pCOMB3H phagemid vector to facilitate selection of new engineered mutants.'

Aborto e eutanásia: dilemas contemporâneos sobre os limites da vida Abortion and euthanasia: contemporary issues on the limits of life

Directory of Open Access Journals (Sweden)

Edlaine de Campos Gomes

2008-01-01

Full Text Available Este artigo analisa a polêmica em torno da determinação dos limites da vida, a partir do pressuposto de que a demarcação das fronteiras entre vida e morte envolve questões culturais, sociais, religiosas e políticas referentes à gestão da pessoa. Debates acerca do aborto e da eutanásia evidenciam concepções morais sobre os direitos individuais que, por sua vez, são passíveis de normatização em cada contexto. Tais temas revelam para além da criação e do desenvolvimento de novas tecnologias médicas, direcionadas à reprodução assistida, medicina fetal e manutenção artificial da vida, seja de prematuros ou de doentes fora de possibilidades de cura valores e posicionamentos, muitas vezes contrastivos. A partir de levantamento de projetos de lei apresentados no âmbito legislativo brasileiro, constatou-se a presença de discursos opostos, oriundos da religião e de defensores da autonomia individual, o que ilustra os dilemas contemporâneos sobre os limites da vida.This article analyzes the controversy surrounding what can be established as the limit of life, from the presumption that the frontier marks between life and death involve cultural, social, religious and political issues referred to personhood management. Debates about abortion and euthanasia make it clear that moral concepts on individual rights can be standardized in each context. These themes reveal beyond new medical technology creation and development, focused on assisted fertilization, fetal medicine and maintaining life artificially, either for premature babies or patients without possibilities of cure values and viewpoints, often opposed. From the survey of law projects, presented within Brazilian legislative field, opposite positions were revealed, from religion and defenders of individual autonomy, which illustrates the contemporary dilemmas on the limits of life.

The Impact of Nonlocal Ammonia on Submicron Particulate Matter and Visibility Degradation in Urban Shanghai

Directory of Open Access Journals (Sweden)

Roeland Cornelis Jansen

2014-01-01

Full Text Available To study the role of submicron particulate matter on visibility degradation in Shanghai, mass concentrations of PM1, secondary inorganic aerosol (SIA in PM1, and SIA precursor gasses were on-line monitored during a 4-week intensive campaign in December 2012. During the campaign, 8 haze periods were identified when on average PM1 mass increased to 62.1 ± 25.6 μg/m3 compared to 30.7 ± 17.1 μg/m3 during clear weather periods. The sum of SIA in PM1 increased in mass concentration during the haze from 14.9 ± 7.4 μg/m3 during clear periods to 29.7 ± 10.7 μg/m3 during the haze periods. Correlation coefficients (R2 of the visibility as function of mass concentrations of SIA species in PM1 show negative exponential relations implying the importance of the SIA species in visibility reduction. The important role of ammonia in SIA formation is recognized and demonstrated. Generally, ammonium neutralizes sulfate and nitrate and the molar equivalent ratio of ammonium versus the sum of sulfate and nitrate increases during the haze episodes. Air mass backward trajectories introducing the haze periods show the impact of nonlocal ammonia on visibility degradation in Shanghai.

Production bias and void swelling in the transient regime under cascade damage conditions

International Nuclear Information System (INIS)

Singh, B.N.; Foreman, A.J.E.

1992-01-01

Molecular dynamics (MD) studies of collision cascades have firmly established that, in addition to clusters of vacancies, clusters of self-interstitial atoms (SIAs) are formed within the cascade volume during the thermal spike phase of a cascade. These clusters are formed in a segregated fashion such that the vacancy-rich core is surrounded by SIA clusters. At temperatures above stage V the vacancies evaporate from the vacancy cluster and diffuse into the medium whereas the SIA clusters remain thermally stable at temperatures even above the peak swelling temperature. This asymmetry in the production of free and mobile vacancies and SIAs gives rise to a production bias. Some of the vacancies evaporating from the vacancy-rich core annihilate at the SIA clusters surrounding it and others escape into the medium. It is this escaping fraction of vacancies which determines the strength of the production bias. Diffusion calculations have been performed to estimate the magnitude of this escaping fraction of vacancies. The necessary cascade parameters for this calculation are obtained from MD simulation experiments. Almost 80% of vacancies retained in the vacancy-rich core of a 20 keV cascade are found to escape the cascade volume containing SIA clusters. We have taken this escape rate to be effective vacancy production rate in the medium and calculated the temporal evolution of SIA clusters, void size and swelling for fully annealed pure copper under neutron irradiation at 523 K. The general trends of the calculated swelling behaviour are found to be in agreement with experimental results. The present calculations provide further validity and support to the concept of production bias. (Author)

Contribution of amygdala CRF neurons to chronic pain.

Science.gov (United States)

Andreoli, Matthew; Marketkar, Tanvi; Dimitrov, Eugene

2017-12-01

We investigated the role of amygdala corticotropin-releasing factor (CRF) neurons in the perturbations of descending pain inhibition caused by neuropathic pain. Forced swim increased the tail-flick response latency in uninjured mice, a phenomenon known as stress-induced analgesia (SIA) but did not change the tail-flick response latency in mice with neuropathic pain caused by sciatic nerve constriction. Neuropathic pain also increased the expression of CRF in the central amygdala (CeAmy) and ΔFosB in the dorsal horn of the spinal cord. Next, we injected the CeAmy of CRF-cre mice with cre activated AAV-DREADD (Designer Receptors Exclusively Activated by Designer Drugs) vectors. Activation of CRF neurons by DREADD/Gq did not affect the impaired SIA but inhibition of CRF neurons by DREADD/Gi restored SIA and decreased allodynia in mice with neuropathic pain. The possible downstream circuitry involved in the regulation of SIA was investigated by combined injections of retrograde cre-virus (CAV2-cre) into the locus ceruleus (LC) and cre activated AAV-diphtheria toxin (AAV-FLEX-DTX) virus into the CeAmy. The viral injections were followed by a sciatic nerve constriction ipsilateral or contralateral to the injections. Ablation of amygdala projections to the LC on the side of injury but not on the opposite side, completely restored SIA, decreased allodynia and decreased ΔFosB expression in the spinal cord in mice with neuropathic pain. The possible lateralization of SIA impairment to the side of injury was confirmed by an experiment in which unilateral inhibition of the LC decreased SIA even in uninjured mice. The current view in the field of pain research attributes the process of pain chronification to abnormal functioning of descending pain inhibition. Our results demonstrate that the continuous activity of CRF neurons brought about by persistent pain leads to impaired SIA, which is a symptom of dysregulation of descending pain inhibition. Therefore, an over

Surface-structure dependence of healing radiation-damage mechanism in nanoporous tungsten

Science.gov (United States)

Duan, Guohua; Li, Xiangyan; Sun, Jingjing; Hao, Congyu; Xu, Yichun; Zhang, Yange; Liu, Wei; Liu, C. S.

2018-01-01

Under nuclear fusion environments, displacement damage in tungsten (W) is usually caused by neutrons irradiation through producing large quantities of vacancies (Vs) and self-interstitial atoms (SIAs). These defects not only affect the mechanical properties of W, but also act as the trap sites for implanted hydrogen isotopes and helium. Nano-porous (NP) W with a high fraction of free surfaces has been developed to mitigate the radiation damage. However, the mechanism of the surface reducing defects accumulation is not well understood. By using multi-scale simulation methods, we investigated the interaction of the SIA and V with different surfaces on across length and time scales. We found that, at a typical operation temperature of 1000 K, surface (1 1 0) preferentially heals radiation damage of W compared with surface (1 0 0) and boundary (3 1 0). On surface (1 1 0), the diffusion barrier for the SIA is only 0.68 eV. The annihilation of the SIA-V happens via the coupled motion of the V segregation towards the surface from the bulk and the two-dimensional diffusion of the SIA on the surface. Such mechanism makes the surface (1 1 0) owe better healing capability. On surface (1 0 0), the diffusion energy barrier for the SIA is 2.48 eV, higher than the diffusion energy barrier of the V in bulk. The annihilation of the SIA-V occurs via the V segregation and recombination. The SIA was found to migrate one-dimensionally along a boundary (3 1 0) with a barrier of 0.21 eV, leading to a lower healing efficiency in the boundary. This study suggested that the on-surface process plays an important role in healing radiation damage of NP W in addition to surface-enhanced diffusion and annihilation near the surface. A certain surface structure renders nano-structured W more radiation-tolerant.

IUTAM Symposium on Inelastic Deformation of Composite Materials Held in Troy, New York on 29 May - 1 June 1990

Science.gov (United States)

1991-01-01

T and A [An A] = A 21 A22J 271 AT a Tk2 (T 2 G k CTY karU k E AC’ TT k k 2a T Ai = _ I -+tan((2-ta-3) k kT Ty 6T uk__2COS(;j+0) T A12 k 3--- +- sin...kinematic deficiency in some inclusions. Applications of this model are made to predict the behavior and deformation texture evolution in initially...Constitutive equations accounting for kinematic deficiency in the crys- talline phase are given. The molecular alignment and the relative softness of the

Attività commerciali e sicurezza: alcuni nodi da affrontare

Directory of Open Access Journals (Sweden)

Sette Raffaella

2010-07-01

Full Text Available La problematica della sicurezza delle categorie produttive è ampia e complessa ed è strettamente collegata al rispetto sia dell’integrità fisica di chi vi lavora, sia del patrimonio d’impresa.

Computer simulation of the interaction between an extended dislocation and radiation defects in the fcc lattice

International Nuclear Information System (INIS)

Kuramoto, E.; Nakamura, Y.; Tsutsumi, T.

1993-01-01

The interaction between an extended dislocation and a radiation-induced defect, especially, a self-interstitial atom (SIA), has been investigated in the model fcc lattice by computer simulation technique. An SIA was absorbed into the core of one of the two partial dislocations of the extended screw dislocation as a crowdion which extends along the dislocation line. Under the applied shear stress this crowdion acted as a pinning point, resulting in irradiation hardening. On the other hand, an SIA was absorbed at the jog site of the extended edge dislocation (at one of the two jog sites on two partial dislocations) and after some relaxation the total jog was shifted to one atomic distance through the spreading out of the strain due to an SIA from one partial side to the other side. (orig.)

Epidemiology of small intestinal atresia in Europe: a register-based study.

LENUS (Irish Health Repository)

Best, Kate E

2012-09-01

The epidemiology of congenital small intestinal atresia (SIA) has not been well studied. This study describes the presence of additional anomalies, pregnancy outcomes, total prevalence and association with maternal age in SIA cases in Europe.

Epidemiology of small intestinal atresia in Europe

DEFF Research Database (Denmark)

Best, Kate E; Tennant, Peter W G; Addor, Marie-Claude

2012-01-01

The epidemiology of congenital small intestinal atresia (SIA) has not been well studied. This study describes the presence of additional anomalies, pregnancy outcomes, total prevalence and association with maternal age in SIA cases in Europe....

A comparison study on the use of Dowex 1 and TEVA-resin in determination of 99Tc in environmental and nuclear coolant samples in a SIA system with ICP-MS detection.

Science.gov (United States)

Kołacińska, Kamila; Samczyński, Zbigniew; Dudek, Jakub; Bojanowska-Czajka, Anna; Trojanowicz, Marek

2018-07-01

This work refers to a comparative study of sorbents widely used in determinations of 99 Tc such as TEVA resin and Dowex 1. Despite having a similar functional group of quaternary amines, both materials represent different chromatographic methods-extraction (TEVA resin) and anion exchange (Dowex 1)-which provides a diverse range of their properties significant in determination of 99 Tc in flow conditions. The comparative tests, carried out in a SIA-LOV (Sequential Injection Analysis-Lab-on-Valve) system combined with mass spectrometric (ICP-MS) detection, considered several factors that are crucial from the standpoint of resin´s utility such as sorption capacity, durability, or selectivity, critical in 99 Tc separation from interferences. The developed and optimized analytical procedure based on the application of the TEVA resin provided determinations of 99 Tc at minimum detectable limit (MDL) 6.00 mBq L -1 in 50 min and has been successfully employed in analyses of samples from nuclear industrial and research units (reactor coolant and sewage) as well as from the river surrounding the nuclear reactor. The method proved to be sufficient for routine analysis of water samples in accordance with EPA standards. The reliability of the method was confirmed in the analysis of the BH standard provided by the NPL for inter-laboratory proficiency tests. The 99 Tc recovery for all real samples was evaluated as 80-100%. Copyright © 2018 Elsevier B.V. All rights reserved.

Nash buksirovshtshik stanet krupneishim / Artur Tooman

Index Scriptorium Estoniae

Tooman, Artur, 1971-

2008-01-01

Puksiirettevõtete SIA PKL ja SIA Ostas Flote ühinemisel tekib Läänemere põhjaosa suurim kompanii, millest pool kuulub Eesti firmale PKL Holding AS ja teine pool tuntud Läti ärimehele Oleg Stepanovile

Axial ratio dependence of the stability of self-interstitials in HCP structures

International Nuclear Information System (INIS)

Peng, Qing; Ji, Wei; Huang, Hanchen; De, Suvranu

2013-01-01

We investigate the effect of the axial ratio (c/a) on the stability of self-interstitial atoms (SIAs) in hexagonal close-packed crystal structures, using hcp-zirconium as a prototype, through density functional theory based ab initio calculations. The axial ratio is found to dominate the relative stability of SIAs over volumetric strains. We observe that below the ideal value of 1.633, the basal octahedral configuration is the most stable. Above the ideal value, the off-plane SIAs are more stable than in-plane ones

Social impact assessment in mining projects in Northern Finland: Comparing practice to theory

Energy Technology Data Exchange (ETDEWEB)

Suopajärvi, Leena, E-mail: leena.suopajarvi@ulapland.fi

2013-09-15

The paper discusses social impact assessments (SIA) for mining projects in light of the international principles and guidelines for such assessments and the academic literature in the field. The data consist of environmental impact assessment (EIA) programmes and reports for six mining projects that have started up in northern Finland in the 2000s. A first observation is that the role of the SIAs in the EIA programmes and reports studied was quite minor: measured in number of pages, the assessments account for three or four percent of the total. This study analyses the data collection, research methodology and conceptual premises used in the SIAs. It concludes that the assessments do not fully meet the high standards of the international principles and guidelines set out for them: for example, elderly men are over-represented in the data and no efforts were made to identify and bring to the fore vulnerable groups. Moreover, the reliability of the assessments is difficult to gauge, because the qualitative methods are not described and where quantitative methods were used, details such as non-response rates to questionnaires are not discussed. At the end of the paper, the SIAs are discussed in terms of Jürgen Habermas' theory of knowledge interests, with the conclusion that the assessments continue the empirical analytical tradition of the social sciences and exhibit a technical knowledge interest. -- Highlights: • Paper investigates social impact assessments in Finnish mining projects. • Role of social impact assessment is minor in whole EIA-process. • Mining SIAs give the voice for elderly men, vulnerable groups are not identified. • Assessment of SIAs is difficult because of lacking transparency in reporting. • SIAs belong to empirical analytical tradition with technical knowledge interest.

Social impact assessment in mining projects in Northern Finland: Comparing practice to theory

International Nuclear Information System (INIS)

Suopajärvi, Leena

2013-01-01

The paper discusses social impact assessments (SIA) for mining projects in light of the international principles and guidelines for such assessments and the academic literature in the field. The data consist of environmental impact assessment (EIA) programmes and reports for six mining projects that have started up in northern Finland in the 2000s. A first observation is that the role of the SIAs in the EIA programmes and reports studied was quite minor: measured in number of pages, the assessments account for three or four percent of the total. This study analyses the data collection, research methodology and conceptual premises used in the SIAs. It concludes that the assessments do not fully meet the high standards of the international principles and guidelines set out for them: for example, elderly men are over-represented in the data and no efforts were made to identify and bring to the fore vulnerable groups. Moreover, the reliability of the assessments is difficult to gauge, because the qualitative methods are not described and where quantitative methods were used, details such as non-response rates to questionnaires are not discussed. At the end of the paper, the SIAs are discussed in terms of Jürgen Habermas' theory of knowledge interests, with the conclusion that the assessments continue the empirical analytical tradition of the social sciences and exhibit a technical knowledge interest. -- Highlights: • Paper investigates social impact assessments in Finnish mining projects. • Role of social impact assessment is minor in whole EIA-process. • Mining SIAs give the voice for elderly men, vulnerable groups are not identified. • Assessment of SIAs is difficult because of lacking transparency in reporting. • SIAs belong to empirical analytical tradition with technical knowledge interest

Generalized Rate Theory for Void and Bubble Swelling and its Application to Delta-Plutonium

Energy Technology Data Exchange (ETDEWEB)

Allen, P. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wall, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wolfer, W. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2016-10-04

A rate theory for void and bubble swelling is derived that allows both vacancies and self-interstitial atoms to be generated by thermal activation at all sinks. In addition, they can also be produced by displacement damage from external and internal radiation. This generalized rate theory (GRT) is applied to swelling of gallium-stabilized δ-plutonium in which α-decay causes the displacement damage. Since the helium atoms produced also become trapped in vacancies, a distinction is made between empty and occupied vacancies. The growth of helium bubbles observed by transmission electron microscopy (TEM) in weapons-grade and in material enriched with Pu238 is analyzed, using different values for the formation energy of self-interstitial atoms (SIA) and two different sets of relaxation volumes for the vacancy and for the SIA. One set allows preferential capture of SIA at dislocations, while the other set gives equal preference to both vacancy and SIA. It is found that the helium bubble diameters observed are in better agreement with GRT predictions if no preferential capture occurs at dislocations. Therefore, helium bubbles in δ-plutonium will not evolve into voids. The helium density within the bubbles remains sufficiently high to cause thermal emission of SIA. Based on a helium density between two to three helium atoms per vacant site, the sum of formation and migration energies must be around 2.0 eV for SIA in δ-plutonium.

The effect of non-genetic factors on the early body weights of Tunisian local goats Efeito de fatores não-genéticos sobre o peso corporal inicial de caprinos na Tunísia

Directory of Open Access Journals (Sweden)

Ouni Mabrouk

2010-05-01

Full Text Available It was evaluated in this study the environmental effects on body weights of goat kids from birth to 150 days of age of Tunisian local goat population, on the basis of 1,656 records obtained from the Arid Areas Institute of Médenine, Tunisia, during 2001-2005. Except for birth weight, individual records were adjusted for standard ages (30, 60, 90, 120 and 150 days using either extrapolation or interpolation on field data. Data were analyzed by GLM procedure and SNK (α = 0.05 means comparison test. The kidding year (2001-2005, kidding month (December, January, February, and March, birth type (single and twins, sex (male and female, coat colour of kid and age of dam (2-10 years were definied as non-genetic factors. Results showed that mean values and standard deviation (SD of body weight at birth (0, 30, 60, 90, 120 and 150 days of age were 2.57 ± 0.52 kg, 4.06 ± 1.16 kg, 6.99 ± 1.87 kg, 8.90 ± 2.46 kg, 11.48 ± 3.35 kg and 13.53 ± 4.80 kg for male and 2.29 ± 0.44 kg, 4.76 ± 1.13 kg, 3.09 ± 1.33 kg, 8.08 ± 2.02 kg, 10.24 ± 2.36 kg and 12.15 ± 6.54 kg for female. The kidding year, birth type and sex had effect on body weights of Tunisian local kids at all ages. The single and male was always heavier than the twins and the females. The birth month had effect on all body weights except for weight at 30 days of age. The age of dam had effect on body weights from 60 to 150 days of age. However, the coat color had no significant effect on all body weights. Environmental effects estimated in this study are important and need to be taken into account for Tunisian local goat management and breeding improvement under harsh conditions.Neste estudo, foram avaliados os efeitos ambientais sobre o peso corporal do nascimento aos 150 dias de idade de caprinos na Tunísia com base em 1.656 registros obtidos em caprinos localizados em zonas áridas do Instituto de Medenine-Tunísia, durante 2001-2005. Exceto para peso ao nascimento, registros

Comparison of surgically induced astigmatism in various incisions in manual small incision cataract surgery.

Science.gov (United States)

Jauhari, Nidhi; Chopra, Deepak; Chaurasia, Rajan Kumar; Agarwal, Ashutosh

2014-01-01

To determine the surgically induced astigmatism (SIA) in Straight, Frown and Inverted V shape (Chevron) incisions in manual small incision cataract surgery (SICS). A prospective cross sectional study was done on a total of 75 patients aged 40y and above with senile cataract. The patients were randomly divided into three groups (25 each). Each group received a particular type of incision (Straight, Frown or Inverted V shape incisions). Manual SICS with intraocular lens (IOL) implantation was performed. The patients were compared 4wk post operatively for uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA) and SIA. All calculations were performed using the SIA calculator version 2.1, a free software program. The study was analyzed using SPSS version 15.0 statistical analysis software. The study found that 89.5% of patients in Straight incision group, 94.2% in Frown incision group and 95.7% in Inverted V group attained BCVA post-operatively in the range of 6/6 to 6/18. Mean SIA was minimum (-0.88±0.61D×90 degrees) with Inverted V incision which was statistically significant. Inverted V (Chevron) incision gives minimal SIA.

Remission of migraine after clipping of saccular intracranial aneurysms

DEFF Research Database (Denmark)

Lebedeva, E R; Busygina, A V; Kolotvinov, V S

2015-01-01

interview. The remission rates of migraine and tension-type headache (TTH) in these patients were compared to 92 patients from a headache center. Diagnoses were made according to the ICHD-2. RESULTS: During 1 year preceding rupture 51 patients with SIA had migraine. During the year after clipping......BACKGROUND: Unruptured saccular intracranial aneurysm (SIA) is associated with an increased prevalence of migraine, but it is unclear whether this is altered by clipping of the aneurysm. The aim of our study was to determine whether remission rate of migraine and other recurrent headaches...... was greater in patients with SIA after clipping than in controls. METHODS: We prospectively studied 87 SIA patients with migraine or other recurrent headaches. They were interviewed about headaches in the preceding year before and 1 year after clipping using a validated semi-structured neurologist conducted...

Trophodynamics and functional feeding groups of North Sea fauna: a combined stable isotope and fatty acid approach

NARCIS (Netherlands)

Kürten, B.; Frutos, I.; Struck, U.; Painting, S.J.; Polunin, N.V.C.; Middelburg, J.J.

The trophodynamics of pelagic and benthic animals of the North Sea, North Atlantic shelf, were assessed using stable isotope analysis (SIA) of natural abundance carbon and nitrogen isotopes, lipid fingerprinting and compound-specific SIA (CSIA) of phospholipid-derived fatty acids (PLFAs).

Trophodynamics and functional feeding groups of North Sea fauna: a combined stable isotope and fatty acid approach

NARCIS (Netherlands)

Kürten, B.; Frutos, I.; Struck, U.; Painting, S.J.; Polunin, N.V.C.; Middelburg, J.J.

2013-01-01

The trophodynamics of pelagic and benthic animals of the North Sea, North Atlantic shelf, were assessed using stable isotope analysis (SIA) of natural abundance carbon and nitrogen isotopes, lipid fingerprinting and compound-specific SIA (CSIA) of phospholipid-derived fatty acids (PLFAs).

Preventing Vaccine-Derived Poliovirus Emergence during the Polio Endgame.

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Margarita Pons-Salort

2016-07-01

Full Text Available Reversion and spread of vaccine-derived poliovirus (VDPV to cause outbreaks of poliomyelitis is a rare outcome resulting from immunisation with the live-attenuated oral poliovirus vaccines (OPVs. Global withdrawal of all three OPV serotypes is therefore a key objective of the polio endgame strategic plan, starting with serotype 2 (OPV2 in April 2016. Supplementary immunisation activities (SIAs with trivalent OPV (tOPV in advance of this date could mitigate the risks of OPV2 withdrawal by increasing serotype-2 immunity, but may also create new serotype-2 VDPV (VDPV2. Here, we examine the risk factors for VDPV2 emergence and implications for the strategy of tOPV SIAs prior to OPV2 withdrawal. We first developed mathematical models of VDPV2 emergence and spread. We found that in settings with low routine immunisation coverage, the implementation of a single SIA increases the risk of VDPV2 emergence. If routine coverage is 20%, at least 3 SIAs are needed to bring that risk close to zero, and if SIA coverage is low or there are persistently "missed" groups, the risk remains high despite the implementation of multiple SIAs. We then analysed data from Nigeria on the 29 VDPV2 emergences that occurred during 2004-2014. Districts reporting the first case of poliomyelitis associated with a VDPV2 emergence were compared to districts with no VDPV2 emergence in the same 6-month period using conditional logistic regression. In agreement with the model results, the odds of VDPV2 emergence decreased with higher routine immunisation coverage (odds ratio 0.67 for a 10% absolute increase in coverage [95% confidence interval 0.55-0.82]. We also found that the probability of a VDPV2 emergence resulting in poliomyelitis in >1 child was significantly higher in districts with low serotype-2 population immunity. Our results support a strategy of focused tOPV SIAs before OPV2 withdrawal in areas at risk of VDPV2 emergence and in sufficient number to raise population

Surgically induced astigmatism after phacoemulsification by temporal clear corneal and superior clear corneal approach: a comparison

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Nikose AS

2018-01-01

Full Text Available Archana Sunil Nikose, Dhrubojyoti Saha, Pradnya Mukesh Laddha, Mayuri Patil Department of Ophthalmology, N.K.P. Salve Institute and LMH, Nagpur, Maharashtra, India Introduction: Cataract surgery has undergone various advances since it was evolved from ancient couching to the modern phacoemulsification cataract surgery. Surgically induced astigmatism (SIA remains one of the most common complications. The introduction of sutureless clear corneal incision has gained increasing popularity worldwide because it offers several advantages over the traditional sutured limbal incision and scleral tunnel. A clear corneal incision has the benefit of being bloodless and having an easy approach, but SIA is still a concern.Purpose: In this study, we evaluated the SIA in clear corneal incisions with temporal approach and superior approach phacoemulsification. Comparisons between the two incisions were done using keratometric readings of preoperative and postoperative refractive status.Methodology: It was a hospital-based prospective interventional comparative randomized control trial of 261 patients conducted in a rural-based tertiary care center from September 2012 to August 2014. The visual acuity and detailed anterior segment and posterior segment examinations were done and the cataract was graded according to Lens Opacification Classification System II. Patients were divided for phacoemulsification into two groups, group A and group B, who underwent temporal and superior clear corneal approach, respectively. The patients were followed up on day 1, 7, 30, and 90 postoperatively. The parameters recorded were uncorrected visual acuity, best-corrected visual acuity, slit lamp examination, and keratometry. The mean difference of SIA between 30th and 90th day was statistically evaluated using paired t-test, and all the analyses were performed using SPSS 18.0 (SPSS Inc. software.Results: The mean postoperative SIA in group A was 0.998 D on the 30th day, which

Uno strumento per la creazione di valore nella realizzazione di edifici sostenibili: la certificazione LEED

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S. Rick Fedrizzi

2014-06-01

Full Text Available Il presente lavoro ha l’obiettivo di delineare gli aspetti chiave della sostenibilità in ambito edilizio focalizzando l’attenzione sul sistema di certificazione LEED® quale strumento “universale” di supporto per la realizzazione, gestione e valutazione di edifici sostenibili. Nella prima parte del lavoro si descrive la rapida diffusione della certificazione LEED nel recente passato quale diretta conseguenza della capacità di questo strumento di rating di adattarsi sia alle specifiche tipologie di edifici, sia alle diversità climatiche e morfologiche dei siti. Nella seconda parte si procede invece a presentare ed analizzare gli aspetti economico-finanziari degli edifici sostenibili con riferimento sia alle metodologie valutative applicabili, sia ai dati della letteratura. Partendo dalle esperienze internazionali in tema di sostenibilità, si procede successivamente a descrivere la situazione italiana, evidenziando la percezione del mercato e le opportunità di sviluppo future.

Self-interstitial atom clusters as obstacles to glide of 1/3{11-bar 00} edge dislocations in α-zirconium

International Nuclear Information System (INIS)

Voskoboynikov, R.E.; Osetsky, Yu.N.; Bacon, D.J.

2005-01-01

Atomic-scale details of interaction of a 1/3 {11-bar 00} edge dislocation with clusters of self-interstitial atoms (SIAs) in α-zirconium has been studied by computer simulation. Four typical clusters are considered. A triangular cluster of five SIAs lying within a basal plane bisected by the dislocation glide plane is not absorbed by the dislocation but acts as a moderately strong obstacle. A 3-D SIA cluster lying across the glide plane is completely absorbed by the dislocation by creation of super-jogs, and is a weak obstacle. Interaction of the dislocation with glissile SIA loops with perfect Burgers vector inclined at 60 deg. to the dislocation glide plane shows that the process depends on the vector orientation. Defects of the two orientations are strong obstacles, and one, which initially forms a sessile segment on the dislocation line, is particularly so

Causas de morte e razões para eutanásia de cães da Mesorregião do Centro Ocidental Rio-Grandense (1965-2004 Causes of death and reasons for euthanasia in dogs from the midland region of the Midwest of Rio Grande do Sul State, Brazil (1965-2004

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Rafael A. Fighera

2008-04-01

Full Text Available Este estudo teve como objetivo principal determinar a prevalência das doenças que culminam em morte ou que fazem com que os cães da Mesorregião do Centro Ocidental Rio-Grandense sejam submetidos à eutanásia. Para isso, foram revisados todos os protocolos de necropsia de cães, arquivados no Laboratório de Patologia Veterinária (LPV da Universidade Federal de Santa Maria (UFSM, realizadas entre janeiro de 1965 e dezembro de 2004. Nos arquivos do LPV-UFSM foram encontrados 4.844 protocolos de necropsia de cães. A distribuição dos casos em relação às categorias de doenças diagnosticadas foi a seguinte: doenças infecciosas e parasitárias (1.693 [35,0%], neoplasmas (378 [7,8%], distúrbios causados por agentes físicos (369 [7,6%], doenças degenerativas (342 [7,1%], intoxicações e toxiinfecções (112 [2,3%], eutanásia por conveniência (101 [2,1%], doenças metabólicas e endocrinológicas (97 [2,0%], distúrbios iatrogênicos (83 [1,7%], distúrbios do desenvolvimento (25 [0,5%], doenças imunomediadas (10 [0,2%] e doenças nutricionais (6 [0,1%]. Outros distúrbios, que incluem doenças multifatoriais ou idiopáticas, contribuíram com 80 (1,6% casos. Dos 4.844 casos, em 1.548 (32,0% não foi possível estabelecer a causa da morte ou a razão para a eutanásia. Doenças infecciosas e parasitárias (principalmente cinomose, parvovirose e verminose intestinal, neoplasmas (principalmente neoplasmas mamários e linfoma, distúrbios causados por agentes físicos (principalmente atropelamento por veículos automotivos e doenças degenerativas (principalmente insuficiência renal crônica, cirrose e insuficiência cardíaca congestiva foram as principais categorias de doenças relacionadas com morte ou eutanásia de cães dessa mesorregião. Entretanto, quando os cães são avaliados de acordo com suas idades, tais categorias possuem prevalências diferentes. As principais causas de morte em filhotes foram as doenças infecciosas e

Antecedent causes of a measles resurgence in the Democratic Republic of the Congo

Science.gov (United States)

Scobie, Heather Melissa; Ilunga, Benoît Kebela; Mulumba, Audry; Shidi, Calixte; Coulibaly, Tiekoura; Obama, Ricardo; Tamfum, Jean-Jacques Muyembe; Simbu, Elisabeth Pukuta; Smit, Sheilagh Brigitte; Masresha, Balcha; Perry, Robert Tyrrell; Alleman, Mary Margaret; Kretsinger, Katrina; Goodson, James

2015-01-01

Introduction Despite accelerated measles control efforts, a massive measles resurgence occurred in the Democratic Republic of the Congo (DRC) starting in mid-2010, prompting an investigation into likely causes. Methods We conducted a descriptive epidemiological analysis using measles immunization and surveillance data to understand the causes of the measles resurgence and to develop recommendations for elimination efforts in DRC. Results During 2004-2012, performance indicator targets for case-based surveillance and routine measles vaccination were not met. Estimated coverage with the routine first dose of measles-containing vaccine (MCV1) increased from 57% to 73%. Phased supplementary immunization activities (SIAs) were conducted starting in 2002, in some cases with sub-optimal coverage (≤95%). In 2010, SIAs in five of 11 provinces were not implemented as planned, resulting in a prolonged interval between SIAs, and a missed birth cohort in one province. During July 1, 2010-December 30, 2012, high measles attack rates (>100 cases per 100,000 population) occurred in provinces that had estimated MCV1 coverage lower than the national estimate and did not implement planned 2010 SIAs. The majority of confirmed case-patients were aged measles virus strains that were previously identified in the region. Conclusion The resurgence was likely caused by an accumulation of unvaccinated, measles-susceptible children due to low MCV1 coverage and suboptimal SIA implementation. To achieve the regional goal of measles elimination by 2020, efforts are needed in DRC to improve case-based surveillance and increase two-dose measles vaccination coverage through routine services and SIAs. PMID:26401224

Social Impact Management Plans : Innovation in corporate and public policy

NARCIS (Netherlands)

Franks, Daniel M.; Vanclay, Frank

Social Impact Assessment (SIA) has traditionally been practiced as a predictive study for the regulatory approval of major projects, however, in recent years the drivers and domain of focus for SIA have shifted. This paper details the emergence of Social Impact Management Plans (SIMPs) and

Social Impact Management Plans : Innovation in corporate and public policy

NARCIS (Netherlands)

Franks, Daniel M.; Vanclay, Frank

2013-01-01

Social Impact Assessment (SIA) has traditionally been practiced as a predictive study for the regulatory approval of major projects, however, in recent years the drivers and domain of focus for SIA have shifted. This paper details the emergence of Social Impact Management Plans (SIMPs) and

Plano de Fortalecimento da Gestão do Turismo (PFGT: uma avaliação ex ante no município de Nísia Floresta (RN

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Richard Medeiros de Araújo

2012-02-01

Full Text Available Atualmente, o Plano de Desenvolvimento do Turismo (Prodetur vem procurando fortalecer institucionalmente os destinos turísticos, a fim de garantir a ampliação e a continuidade das melhorias estruturais já realizadas quando da primeira fase do programa governamental, e ao mesmo tempo dotar os municípios de uma gestão pública mais eficiente, em que deverá também considerar o turismo como o eixo central na formulação e gerenciamento das políticas públicas municipais com foco no desenvolvimento local. Para tanto, o Prodetur lançou, no Rio Grande do Norte, o Plano de Fortalecimento da Gestão do Turismo, do Patrimônio Natural e Cultural em 2009. A pesquisa objetiva avaliar, de forma ex ante, a viabilidade da implementação do referido plano governamental no município de Nísia Floresta (RN. Adotaram-se as seis dimensões do modelo teórico de Draibe (2001 conjugadas com o modelo de Neves (1996 para conduzir a pesquisa. Metodologicamente, optou-se por uma abordagem qualitativa, na qual foram buscadas análises de documentos como o diagnóstico estratégico, o plano de ação proposto e realização de entrevistas semiestruturadas com alguns secretários municipais. Usou-se a análise de conteúdo como técnica de tratamento dos conteúdos das entrevistas e foram feitas observações não participantes. Assim foi possível desenhar a pesquisa avaliativa, caracterizando o momento administrativo e político atual e como esse desenho poderia interferir na implementação do plano avaliado. Conclui-se que o município não apresenta condições institucionais suficientes para a implementação do Plano Governamental financiado com recursos federais.

Rilievo terrestre dell’ambiente urbano con tecnologie a scansione: un test sulla città-industria di Dalmine

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Luigi Colombo

2014-12-01

Full Text Available Il patrimonio edilizio urbano è un bene che caratterizza l’identità dell’uomo che con esso ha vissuto; la conoscenza della realtà originaria, la conservazione e valorizzazione nel tempo comportano interventi di tipo documentale che possono interessare sia gli aspetti costruttivi degli edifici, connessi a dimensioni e geo-localizzazione, sia quelli legati alla forma urbana, sia ancora altri più specifici di tipo storico-artistico e materico. Le nuove tecnologie laser di misura terrestre, integrate da sensori di posizionamento e fotografici, consentono di rilevare in tempi ridotti e di rappresentare anche spazialmente sia singole unità edilizie sia interi insediamenti urbani. Le grandi quantità di dati acquisiti costituiscono un arricchimento della conoscenza geometrica di base, fornita in genere da rappresentazioni cartografiche “vettoriali o raster”. Il lavoro descrive un test di scansione laser, statica e cinematica, avviato sul territorio di Dalmine (Bergamo nell’ambito di un programma di interventi comunali di tutela paesaggistica, conservazione dei caratteri costruttivi e valorizzazione degli insediamenti storici della città, realizzati negli anni venti del secolo scorso e identificativi del suo passato di città-industria. L’approccio al rilievo tende altresì a validare una procedura operativa, basata su componenti tecnologiche innovative, semplice, sufficientemente economica e convenientemente applicabile all’indagine su aree urbane.

Individual Impact of Distinct Polysialic Acid Chain Lengths on the Cytotoxicity of Histone H1, H2A, H2B, H3 and H4

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Kristina Zlatina

2017-12-01

Full Text Available Neutrophils are able to neutralize pathogens by phagocytosis, by the release of antimicrobial components, as well as by the formation of neutrophil extracellular traps (NETs. The latter possibility is a DNA-meshwork mainly consisting of highly concentrated extracellular histones, which are not only toxic for pathogens, but also for endogenous cells triggering several diseases. To reduce the negative outcomes initiated by extracellular histones, different approaches like antibodies against histones, proteases, and the polysaccharide polysialic acid (polySia were discussed. We examined whether each of the individual histones is a binding partner of polySia, and analyzed their respective cytotoxicity in the presence of this linear homopolymer. Interestingly, all of the histones (H1, H2A, H2B, H3, and H4 seem to interact with α2,8-linked sialic acids. However, we observed strong differences regarding the required chain length of polySia to bind histone H1, H2A, H2B, H3, and H4. Moreover, distinct degrees of polymerization were necessary to act as a cytoprotective agent in the presence of the individual histones. In sum, the outlined results described polySia-based strategies to bind and/or to reduce the cytotoxicity of individual histones using distinct polySia chain length settings.

Is social isolation/alienation confounded with, and non-independent of, emotional distress in its association with early onset of coronary artery disease?

Science.gov (United States)

Ketterer, Mark; Rose, Benjamin; Knysz, Walter; Farha, Amjad; Deveshwar, Sangita; Schairer, John; Keteyian, Steven J

2011-03-01

Both emotional distress (ED) and social isolation/alienation (SI/A) have been found to prospectively predict adverse cardiac events, but few studies have tested the confounding/redundancy of these measures as correlates/predictors of outcomes. In this study, 163 patients with documented coronary artery disease (CAD) were interviewed for multiple indices of SI/A and administered the Symptom Checklist 90 - Revised (SCL90R). A spouse or friend provided an independent rating of ED using the spouse/friend version of the Ketterer Stress Symptom Frequency Checklist (KSSFC). The measures of ED and SI/A covaried. All three scales from the KSSFC (depression, anxiety, and "AIAI" - aggravation, irritation, anger, and impatience), and three scales from the SCL90R (anxiety, depression, and psychoticism), were associated with early Age at Initial Diagnosis (AAID) of CAD. Neither three scales derived from the SCL90R (shyness, feeling abused, and feeling lonely) nor the interview indices of SI/A (married, living alone, having a confidant, self description as a lone wolf, and self-description as lonely) were associated with early AAID. Thus, it is concluded that the present results indicate that ED and SI/A are confounded and that, even when tested head-to-head in a multivariate analysis, only ED is associated with AAID.

Aastahitt 2008. Chalice "Supervõimed". Laura "Destiny" / Kallervo Karu

Index Scriptorium Estoniae

Karu, Kallervo

2009-01-01

Aastahitt 2008 valimisest (võitis Kerli Kõivu lugu "Walking on Air") ja kontserdist ETV ja Raadio 2 koostööna Tallinnas Club von Überblingenis. Heliplaadist. Laura Põldvere esitatavast eurolaulust

Miljardär Armin Karu hakkab telestaariks / Heidit Kaio

Index Scriptorium Estoniae

Kaio, Heidit, 1971-

2007-01-01

TV3 on Eesti Ekspressi andmetel jõudmas kokkuleppele, et tuua järgmisest hooajast ekraanile saatesari, mida võiks nimetada "Suurim tööintervjuu". Ameerika Ühendriikides tuli saade ekraanile 2004. aastal, kus seda juhtis miljardär Donald Trump

A Dinâmica da Expansão do Setor Sucroalcooleiro no estado de Goiás e as Contribuições Socioeconômica no Município de Goianésia

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Marly Alves dos Reis

2017-03-01

The sugar cane for a number of reasons becomes the only source of ethanol, with the creation of Proálcool in the 1970s the government launches numerous incentives to finance new projects, involving various ministries, among other committees. Same period occurred the process of expanding the agricultural frontier in the state of Goiás subsidized by the National Development Plan (PND to encourage the expansion of agricultural technology in the Cerrado, especially of soybean (Oliveira, 1997; Miziara, 2005; Silva and Miziara, 2011. In 2006, the same expansion process occurs when the government launched the National Agro-Energy Plan (NAP to stimulate the production of renewable energy, especially for the production of ethanol from cane sugar (Embrapa, 2006. Since then planted area increases progressively, and according to the latest data in six years the increase was 250 %, equivalent of 200,048 to 697,541 hectares between 2005 and 2011 (IBGE, 2012. In mesoregion South Goiás concentrates 72 % of this total (IBGE, 2012 as well as 31 of the 45 plants of cane sugar in the state of Goiás (CONAB, 2012 and UDOP, 2012. Thus, it is evident the need to investigate the dynamics of expansion of cane sugar in the state of Goiás and assess the socioeconomic contributions of municipalities whose expansion presents significant as the municipality of Goianésia, constituting the objective of this work. Key-words: Sugarcane Expansion, Expansion of Agricultural Frontier, Socioeconomic Impacts.

Uus sünagoog pani juudid tantsima / Peeter Kuimet, Kaia Otti

Index Scriptorium Estoniae

Kuimet, Peeter

2007-01-01

Tallinnas Karu tänaval avati 16. mail 2007 uus juudi sünagoog, avamistseremoonial viibisid Iisraeli asepeaminister Shimon Peres, Eesti president Toomas Hendrik Ilves, peaminister Andrus Ansip, Venemaa pearabi Berl Lazar, Iisraeli pearabi Yona Metzger ja sünagoogi suurrahastaja Aleksander Bronshtein. President Toomas Hendrik Ilves viitas oma kõnes paralleelidele eestlaste ja juutide ajaloos. Vt. samas: Juutide usk, kombed ja toit; Sünagoogi avamist kommenteerivad meediaõppejõud Hagi Shein, dirigent Eri Klas. Vt. samas: Peres: elevantide keskel on väikestel raske magada. Ilmunud ka: Postimees : na russkom jazõke 17. mai 2007, lk. 2; Narvskaja Gazeta, 19. mai 2007, lk. 6 (autor Ksenia Repson)

Terra e lavoro: due questioni apparentemente dimenticate, di nuovo nell'agenda europea

NARCIS (Netherlands)

Ploeg, van der J.D.

2012-01-01

Questo articolo discute l’agricoltura contadina come la principale istituzione-lavoro in Europa. Si afferma che sia il lavoro sia la terra sono socialmente difniti. Essi sono materialmente costituiti sulla base di tali definizioni e, laddove le definizioni sociali mutano, il significato, l’uso e e

Confirmatory Factor Analysis of the Combined Social Phobia Scale and Social Interaction Anxiety Scale: Support for a Bifactor Model

Science.gov (United States)

Gomez, Rapson; Watson, Shaun D.

2017-01-01

For the Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS) together, this study examined support for a bifactor model, and also the internal consistency reliability and external validity of the factors in this model. Participants (N = 526) were adults from the general community who completed the SPS and SIAS. Confirmatory factor analysis (CFA) of their ratings indicated good support for the bifactor model. For this model, the loadings for all but six items were higher on the general factor than the specific factors. The three positively worded items had negligible loadings on the general factor. The general factor explained most of the common variance in the SPS and SIAS, and demonstrated good model-based internal consistency reliability (omega hierarchical) and a strong association with fear of negative evaluation and extraversion. The practical implications of the findings for the utilization of the SPS and SIAS, and the theoretical and clinical implications for social anxiety are discussed. PMID:28210232

Confirmatory Factor Analysis of the Combined Social Phobia Scale and Social Interaction Anxiety Scale: Support for a Bifactor Model.

Science.gov (United States)

Gomez, Rapson; Watson, Shaun D

2017-01-01

For the Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS) together, this study examined support for a bifactor model, and also the internal consistency reliability and external validity of the factors in this model. Participants ( N = 526) were adults from the general community who completed the SPS and SIAS. Confirmatory factor analysis (CFA) of their ratings indicated good support for the bifactor model. For this model, the loadings for all but six items were higher on the general factor than the specific factors. The three positively worded items had negligible loadings on the general factor. The general factor explained most of the common variance in the SPS and SIAS, and demonstrated good model-based internal consistency reliability (omega hierarchical) and a strong association with fear of negative evaluation and extraversion. The practical implications of the findings for the utilization of the SPS and SIAS, and the theoretical and clinical implications for social anxiety are discussed.

Psychometric properties of the Social Interaction Anxiety Scale and separation criterion between Spanish youths with and without subtypes of social anxiety.

Science.gov (United States)

Zubeidat, Ihab; Salinas, José María; Sierra, Juan Carlos; Fernández-Parra, Antonio

2007-01-01

In this study, we analyzed the reliability and validity of the Social Interaction Anxiety Scale (SIAS) and propose a separation criterion between youths with specific and generalized social anxiety and youths without social anxiety. A sample of 1012 Spanish youths attending school completed the SIAS, the Liebowitz Social Anxiety Scale, the Social Avoidance and Distress Scale, the Fear of Negative Evaluation Scale, the Youth Self-Report for Ages 11-18 and the Minnesota Multiphasic Personality Inventory-Adolescent. The factor analysis suggests the existence of three factors in the SIAS, the first two of which explain most of the variance of the construct assessed. Internal consistency is adequate in the first two factors. The SIAS features an adequate theoretical validity with the scores of different variables related to social interaction. Analysis of the criterion scores yields three groups pertaining to three clearly differentiated clusters. In the third cluster, two of social anxiety groups - specific and generalized - have been identified by means of a quantitative separation criterion.

Comparing short forms of the Social Interaction Anxiety Scale and the Social Phobia Scale.

Science.gov (United States)

Carleton, R Nicholas; Thibodeau, Michel A; Weeks, Justin W; Teale Sapach, Michelle J N; McEvoy, Peter M; Horswill, Samantha C; Heimberg, Richard G

2014-12-01

The Social Interaction Anxiety Scale (SIAS) and the Social Phobia Scale (SPS; Mattick & Clarke, 1998) are companion scales developed to measure anxiety in social interaction and performance situations, respectively. The measures have strong discriminant and convergent validity; however, their factor structures remain debated, and furthermore, the combined administration length (i.e., 39 items) can be prohibitive for some settings. There have been 4 attempts to assess the factor structures of the scales and reduce the item content: the 14-item Social Interaction Phobia Scale (SIPS; Carleton et al., 2009), the 12-item SIAS-6/SPS-6 (Peters, Sunderland, Andrews, Rapee, & Mattick, 2012), the 21-item abbreviated SIAS/SPS (ASIAS/ASPS; Kupper & Denollet, 2012), and the 12-item Readability SIAS and SPS (RSIAS/RSPS; Fergus, Valentiner, McGrath, Gier-Lonsway, & Kim, 2012). The current study compared the short forms on (a) factor structure, (b) ability to distinguish between clinical and non-clinical populations, (c) sensitivity to change following therapy, and (d) convergent validity with related measures. Participants included 3,607 undergraduate students (55% women) and 283 patients with social anxiety disorder (43% women). Results of confirmatory factor analyses, sensitivity analyses, and correlation analyses support the robust utility of items in the SIPS and the SPS-6 and SIAS-6 relative to the other short forms; furthermore, the SIPS and the SPS-6 and SIAS-6 were also supported by convergent validity analyses within the undergraduate sample. The RSIAS/RSPS and the ASIAS/ASPS were least supported, based on the current results and the principle of parsimony. Accordingly, researchers and clinicians should consider carefully which of the short forms will best suit their needs. (c) 2014 APA, all rights reserved.

Blood pressure shifts resulting from a concealed arteriovenous fistula associated with an iliac aneurysm: a case report.

Science.gov (United States)

Doi, Shintaro; Motoyama, Yoshiaki; Ito, Hiromi

2016-01-01

A solitary iliac aneurysm (SIA) is more uncommon than an abdominal aortic aneurysm. The aneurysm is located in the deep pelvis and is diagnosed when it reaches a large size with symptoms of compression around adjacent structures and organs or when it ruptures. A definite diagnosis of an arteriovenous fistula (AVF) associated with a SIA is difficult preoperatively because there might not be enough symptoms and time for diagnosis. Here, we present a patient with asymptomatic rupture of SIA into the common iliac vein with characteristic blood pressure shifts. A 41-year-old man with a huge SIA underwent aortobifemoral graft replacement. Preoperatively, his blood pressure showed characteristic shifts for one or two heartbeats out of five beats, indicating that an AVF was present and that the shunt was about to having a high flow. During surgery, an AVF associated with the SIA was found to be concealed owing to compression from the huge iliac artery aneurysm, and the shunt showed a high flow, resulting in shock during the surgery. No complications were noted after aortobifemoral graft replacement. Postoperatively, we noted an enhanced paravertebral vein on computed tomography (CT), which indicated the presence of an AVF. Definite diagnosis of an AVF offers advantages in surgical and anesthetic management. We emphasize that a large SIA can push the iliac vein and occlude an AVF laceration, concealing the enhancement of the veins in the arterial phase on CT. Blood pressure shifts might predict the existence of a concealed AVF that has a large shunt. Even if the vena cava and the iliac veins are not enhanced on CT, anesthesiologists should carefully determine whether their distal branches are enhanced.

OBJECT KINETIC MONTE CARLO SIMULATIONS OF RADIATION DAMAGE IN BULK TUNGSTEN

Energy Technology Data Exchange (ETDEWEB)

Nandipati, Giridhar; Setyawan, Wahyu; Heinisch, Howard L.; Roche, Kenneth J.; Kurtz, Richard J.; Wirth, Brian D.

2015-09-22

We used our recently developed lattice based OKMC code; KSOME [1] to carryout simulations of radiation damage in bulk W. We study the effect of dimensionality of self interstitial atom (SIA) diffusion i.e. 1D versus 3D on the defect accumulation during irradiation with a primary knock-on atom (PKA) energy of 100 keV at 300 K for the dose rates of 10-5 and 10-6 dpa/s. As expected 3D SIA diffusion significantly reduces damage accumulation due to increased probability of recombination events. In addition, dose rate, over the limited range examined here, appears to have no effect in both cases of SIA diffusion.

Internet 2.0 e Open Source per la didattica scolastica

Directory of Open Access Journals (Sweden)

Elisa Spadavecchia

2009-10-01

Full Text Available E'€ possibile individuare strumenti e strategie per condividere buone pratiche fra colleghi, comunicare e sfruttare efficacemente le capacità€ di apprendimento degli studenti, il tutto a costi molto contenuti? E come? Con un semplice laptop, i tools cooperativi del Web 2.0 e il software Open Source. L’e-learning, sia nei suoi risvolti formali (le cosiddette “piattaforme” che informali (wiki, blog, podcast, VOIP, può€ diventare un agevolatore o un integratore della didattica scolastica, sia consentendo una maggiore individualizzazione dei percorsi, sia mettendo lo studente in condizione di favorire tecniche di sostegno aggiuntivo, peer tutoring ecc.

Developments in Social Impact Assessment : An introduction to a collection of seminal research papers

NARCIS (Netherlands)

Vanclay, Frank; Vanclay, Frank

2014-01-01

This Edward Elgar research collection comprises 50 of the key journal articles in the field of social impact assessment (SIA) as it has developed over time. As discussed in more detail below and in the papers in this collection, the general understanding of SIA has changed over time, and will likely

A general treatment of one- to three-dimensional diffusion reaction kinetics of interstitial clusters: Implications for the evolution of voids

International Nuclear Information System (INIS)

Trinkaus, H.; Singh, B.N.; Golubov, S.I.

2008-05-01

In recent years, it has been shown that a number of striking features in the microstructural evolution occurring in metals under cascade damage generating irradiation (e.g. enhanced swelling near grain boundaries, decoration of dislocations with SIA loops, saturation of void growth and void lattice formation) can be rationalised in terms of intra-cascade clustering of vacancies and self-interstitial atoms (SIAs), differences in the thermal stability and mobility of the resulting clusters and one-dimensional (1D) glide diffusion of SIA clusters ('production bias model'). The 1D diffusion of SIA clusters is generally disturbed by changes between equivalent 1D diffusion paths and by transversal diffusion by self-climb, resulting in diffusion reaction kinetics between the 1D and 3D limiting cases. In this paper, a general treatment of such kinetics operating in systems containing random distributions of sinks is presented. The complicated partial sink strengths of different components of the system for the annihilation of SIA clusters are expressed by those for the simple 1D and 3D limiting cases. The effects of direction changes and transversal diffusion are first considered separately and are then combined. The significance of the present treatment for damage accumulation under cascade damage conditions is illustrated by applying it to the discussion of void growth characteristics, particularly of the conditions for saturation of void growth. (au)

A general treatment of one- to three-dimensional diffusion reaction kinetics of interstitial clusters: Implications for the evolution of voids

Energy Technology Data Exchange (ETDEWEB)

Trinkaus, H. (Inst. Festkoerperforschung, Forschungszentrum Juelich (Germany)); Singh, B.N. (Risoe DTU, Roskilde (Denmark)); Golubov, S.I. (Oak Ridge National Lab., Materials Science and Technology Div., TN (United States))

2008-05-15

In recent years, it has been shown that a number of striking features in the microstructural evolution occurring in metals under cascade damage generating irradiation (e.g. enhanced swelling near grain boundaries, decoration of dislocations with SIA loops, saturation of void growth and void lattice formation) can be rationalised in terms of intra-cascade clustering of vacancies and self-interstitial atoms (SIAs), differences in the thermal stability and mobility of the resulting clusters and one-dimensional (1D) glide diffusion of SIA clusters ('production bias model'). The 1D diffusion of SIA clusters is generally disturbed by changes between equivalent 1D diffusion paths and by transversal diffusion by self-climb, resulting in diffusion reaction kinetics between the 1D and 3D limiting cases. In this paper, a general treatment of such kinetics operating in systems containing random distributions of sinks is presented. The complicated partial sink strengths of different components of the system for the annihilation of SIA clusters are expressed by those for the simple 1D and 3D limiting cases. The effects of direction changes and transversal diffusion are first considered separately and are then combined. The significance of the present treatment for damage accumulation under cascade damage conditions is illustrated by applying it to the discussion of void growth characteristics, particularly of the conditions for saturation of void growth. (au)

In-situ field-ion microscope study of the recovery behavior of heavy metal ion-irradiated tungsten, tungsten (rhenium) alloys and molybdenum

International Nuclear Information System (INIS)

Nielsen, C.H.

1977-06-01

Three field ion microscope (FIM) experiments were carried out to study the annealing behavior of heavy ion irradiated tungsten, tungsten (rhenium) alloys and molybdenum. The first experiment dealt with the stage I long-range migration of tungsten self interstitial atoms (SIAs) in high purity tungsten of resistivity ratio, R = 24,000 (R = rho 300 /rho 4 . 2 , where rho 300 and rho 4 . 2 are the room temperature and 0 0 C resistivities). The FIM specimens were irradiated in situ at 18 K with 30 keV W + ions to an average dose of 5 x 10 12 ions cm -2 and subsequently examined by the pulsed-field evaporation technique. The second experiment dealt with the phenomenon of impurity atom trapping of SIAs during long-range migration. It was shown that rhenium atoms in a tungsten matrix tend to capture tungsten SIAs and remain bound up to temperatures as high as 390 K. The final experiment was concerned with the low temperature annealing kinetics of irradiated molybdenum. High purity molybdenum of resistivity ratio R = 5700 was irradiated at 10 K with 30 keV Mo + ions to a dose of approximately 5 x 10 12 ions cm -2 . The results indicated that the electric field has only a minimal effect on the SIA annealing kinetics. This tends to strengthen the contention that the molybdenum SIA becomes mobile at 32 K

Sequential-Injection Analysis: Principles, Instrument Construction, and Demonstration by a Simple Experiment

Science.gov (United States)

Economou, A.; Tzanavaras, P. D.; Themelis, D. G.

2005-01-01

The sequential-injection analysis (SIA) is an approach to sample handling that enables the automation of manual wet-chemistry procedures in a rapid, precise and efficient manner. The experiments using SIA fits well in the course of Instrumental Chemical Analysis and especially in the section of Automatic Methods of analysis provided by chemistry…

Special Interest Areas and Employment Skills Programming for Secondary Students with Autism

Science.gov (United States)

Bross, Leslie Ann; Travers, Jason C.

2017-01-01

Many students with autism spectrum disorder (ASD) have specialized interests and passions that are highly reinforcing. Such special interest areas (SIAs) are more than mere hobbies or simple curiosities. Rather, the SIAs of an individual with autism may be characterized by (a) significant depth and breadth of knowledge about the area, (b)…

Integrated package approach in delivering interventions during immunisation campaigns in a complex environment in Papua New Guinea: a case study.

Science.gov (United States)

Vince, John David; Datta, Siddhartha Sankar; Toikilik, Steven; Lagani, William

2014-08-06

Papua New Guinea's difficult and varied topography, poor transport infrastructure, changing dynamics of population and economy in recent times and understaffed and poorly financed health service present major challenges for successful delivery of vaccination and other preventative health interventions to both the rural majority and urban populations, thereby posing risks for vaccine preventable disease outbreaks in the country. The country has struggled to meet the vaccination coverage targets required for the eradication of poliomyelitis and elimination of measles. Escalation of inter and intra country migration resulting from major industrial developments, particularly in extraction industries, has substantially increased the risk of infectious disease importation. This case study documents the evolution of immunisation programmes since the introduction of supplementary immunisation activities (SIAs). Single antigen SIAs have advantages and disadvantages. In situations in which the delivery of preventative health interventions is difficult, it is likely that the cost benefit is greater for multiple than for single intervention. The lessons learned from the conduct of single antigen SIAs can be effectively used for programmes delivering multiple SIA antigens, routine immunisations, and other health interventions. This paper describes a successful and cost effective multiple intervention programme in Papua New Guinea. The review of the last SIA in Papua New Guinea showed relatively high coverage of all the interventions and demonstrated the operational feasibility of delivering multiple interventions in resource constrained settings. Studies in other developing countries such as Lesotho and Ethiopia have also successfully integrated health interventions with SIA. In settings such as Papua New Guinea there is a strong case for integrating supplementary immunisation activity with routine immunisation and other health interventions through a comprehensive outreach

Metabolism of vertebrate amino sugars with N-glycolyl groups: resistance of α2-8-linked N-glycolylneuraminic acid to enzymatic cleavage.

Science.gov (United States)

Davies, Leela R L; Pearce, Oliver M T; Tessier, Matthew B; Assar, Siavash; Smutova, Victoria; Pajunen, Maria; Sumida, Mizuki; Sato, Chihiro; Kitajima, Ken; Finne, Jukka; Gagneux, Pascal; Pshezhetsky, Alexey; Woods, Robert; Varki, Ajit

2012-08-17

The sialic acid (Sia) N-acetylneuraminic acid (Neu5Ac) and its hydroxylated derivative N-glycolylneuraminic acid (Neu5Gc) differ by one oxygen atom. CMP-Neu5Gc is synthesized from CMP-Neu5Ac, with Neu5Gc representing a highly variable fraction of total Sias in various tissues and among different species. The exception may be the brain, where Neu5Ac is abundant and Neu5Gc is reported to be rare. Here, we confirm this unusual pattern and its evolutionary conservation in additional samples from various species, concluding that brain Neu5Gc expression has been maintained at extremely low levels over hundreds of millions of years of vertebrate evolution. Most explanations for this pattern do not require maintaining neural Neu5Gc at such low levels. We hypothesized that resistance of α2-8-linked Neu5Gc to vertebrate sialidases is the detrimental effect requiring the relative absence of Neu5Gc from brain. This linkage is prominent in polysialic acid (polySia), a molecule with critical roles in vertebrate neural development. We show that Neu5Gc is incorporated into neural polySia and does not cause in vitro toxicity. Synthetic polymers of Neu5Ac and Neu5Gc showed that mammalian and bacterial sialidases are much less able to hydrolyze α2-8-linked Neu5Gc at the nonreducing terminus. Notably, this difference was not seen with acid-catalyzed hydrolysis of polySias. Molecular dynamics modeling indicates that differences in the three-dimensional conformation of terminal saccharides may partly explain reduced enzymatic activity. In keeping with this, polymers of N-propionylneuraminic acid are sensitive to sialidases. Resistance of Neu5Gc-containing polySia to sialidases provides a potential explanation for the rarity of Neu5Gc in the vertebrate brain.

29 CFR (non - mandatory) Appendix C to Subpart L of Part 1926-List of National Consensus Standards

Science.gov (United States)

2010-07-01

... 29 Labor 8 2010-07-01 2010-07-01 false mandatory) Appendix C to Subpart L of Part 1926-List of National Consensus Standards (Non Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... Consensus Standards ANSI/SIA A92.2-1990Vehicle-Mounted Elevating and Rotating Aerial Devices ANSI/SIA A92.3...

da james joyce a john assurbanipal smith. la (de)legittimazione del ...

African Journals Online (AJOL)

User

Vedremo come Eco sembri a prima vista allineato con queste posizioni, ma anche come il suo discorso sul comico non sia privo di contraddizioni e non costituisca fino in fondo una legittimazione. Per prima cosa bisognerebbe fermarsi e dare una definizione di cosa sia il comico, ma rinuncio subito. In questo mi sento ...

Environmental Justice and Sustainability Impact Assessment: In Search of Solutions to Ethnic Conflicts Caused by Coal Mining in Inner Mongolia, China

Directory of Open Access Journals (Sweden)

Lee Liu

2014-12-01

Full Text Available The Chinese government adopted more specific and stringent environmental impact assessment (EIA guidelines in 2011, soon after the widespread ethnic protests against coal mining in Inner Mongolia. However, our research suggests that the root of the ethnic tension is a sustainability problem, in addition to environmental issues. In particular, the Mongolians do not feel they have benefited from the mining of their resources. Existing environmental assessment tools are inadequate to address sustainability, which is concerned with environmental protection, social justice and economic equity. Thus, it is necessary to develop a sustainability impact assessment (SIA to fill in the gap. SIA would be in theory and practice a better tool than EIA for assessing sustainability impact. However, China’s political system presents a major challenge to promoting social and economic equity. Another practical challenge for SIA is corruption which has been also responsible for the failing of EIA in assessing environmental impacts of coal mining in Inner Mongolia. Under the current political system, China should adopt the SIA while continuing its fight against corruption.

Assemblare il genere nello sport: il caso controverso di Caster Semenya

Directory of Open Access Journals (Sweden)

Serena Naim

2013-04-01

Full Text Available Questa ricerca mira a indagare le strategie di gestione delle “anomalie” di genere in contesti di forte segregazione tra i sessi. In particolare, il tema che ci interessa trattare in queste pagine riguarda il modo in cui il mondo sportivo affronta, sia in termini tecnico-scientifici sia in termini narrativi, i casi di atlete che, per caratteristiche fisiche di vario tipo, non rientrano negli standard pensati per chi compete nelle categorie femminili. Cercheremo di capire in che modo l'approccio narrativo si intreccia a quello tecnico-scientifico, e quali saranno le possibili soluzioni al problema. Lo sport si rivela in questo senso un terreno estremamente favorevole allo svolgimento di questa ricerca, per tre caratteristiche particolari: in primo luogo, come dicevamo, vige una stretta separazione tra uomini e donne; in secondo luogo, è oggetto di grande interesse mediatico e dunque di una florida produzione narrativa; infine, è un ambito fortemente medicalizzato, sia per questioni di salute psico-fisica degli atleti, sia per questioni di controllo del doping.

Institutionalizing social impact assessment in Bangladesh resource management: limitations and opportunities

International Nuclear Information System (INIS)

Momtaz, Salim

2005-01-01

Consideration of social issues in environmental impact assessment (EIA) of development projects has been an integral part of project cycle since the inception of EIA in Bangladesh in the early 1990s. This paper examines the emergence of social impact assessment (SIA) in Bangladesh environmental management and its institutionalization. It reveals that although SIA does not have a statutory status like EIA, social dimensions are firmly established in donor funded poverty alleviation projects. It is proposed that SIA is given a clear legislative mandate. The Department of Environment (DOE) - the agency that looks after the implementation of EIA on behalf of the government--needs to be strengthened and transparent in order to play a more effective role

[Applications of stable isotope analysis in the trophic ecology studies of cephalopods].

Science.gov (United States)

Li, Yun-Kai; Gong, Yi; Chen, Xin-Jun

2014-05-01

Cephalopods play an important role in marine food webs, however, knowledge about their complex life history, especially their feeding ecology, remains limited. With the rapidly increasing use of stable isotope analysis (SIA) in ecology, it becomes a powerful tool and complement of traditional methods for investigating the trophic ecology and migration patterns of invertebrates. Here, after summarizing the current methods for trophic ecology investigation of cephalopods, applications of SIA in studying the trophic ecology of cephalopods were reviewed, including the key issues such as standardization of available tissues for SIA analyzing, diet shift and migration patterns of cephalopods, with the aim of advancing its application in the biology of cephalopods in the future.

Sarah Zappulla Muscarà-Enzo Zappulla, Gabriele d'Annunzio ...

African Journals Online (AJOL)

User

E fu D'Annunzio a curare il libretto della Figlia di Iorio per la musica di. Alberto Franchetti (Scala di Milano, 29 marzo 1906). Il volume offre dunque un panorama fitto di informazioni, commentate con rigore critico, storico e filologico, nel quale figurano sia il testo originale della tragedia sia le tre versioni dialettali: con un.

Development of the Sport Injury Anxiety Scale

Science.gov (United States)

Rex, Camille C.; Metzler, Jonathan N.

2016-01-01

The purpose of this research was to develop a measure of sport injury anxiety (SIA), defined as the tendency to make threat appraisals in sport situations where injury is seen as possible and/or likely. The Sport Injury Anxiety Scale (SIAS) was developed in three stages. In Stage 1, expert raters evaluated items to determine their adequacy. In…

Questioning the 'exotic' in two Italian travellers' accounts of New ...

African Journals Online (AJOL)

L'articolo studia le testimonianze di due missionari italiani presenti in Nuova Zelanda tra la fine dell'Ottocento e l'inizio del Novecento: il benedettino Dom Felice Vaggioli e il salesiano Giuseppe Capra. Sia l'uno sia l'altro, attratti dalle bellezze naturali del paese descritto come una sorta di esotico nuovo Eden, finirono col ...

Quantifying the quality of hand movement in stroke patients through three-dimensional curvature

Directory of Open Access Journals (Sweden)

Osu Rieko

2011-10-01

Full Text Available Abstract Background To more accurately evaluate rehabilitation outcomes in stroke patients, movement irregularities should be quantified. Previous work in stroke patients has revealed a reduction in the trajectory smoothness and segmentation of continuous movements. Clinically, the Stroke Impairment Assessment Set (SIAS evaluates the clumsiness of arm movements using an ordinal scale based on the examiner's observations. In this study, we focused on three-dimensional curvature of hand trajectory to quantify movement, and aimed to establish a novel measurement that is independent of movement duration. We compared the proposed measurement with the SIAS score and the jerk measure representing temporal smoothness. Methods Sixteen stroke patients with SIAS upper limb proximal motor function (Knee-Mouth test scores ranging from 2 (incomplete performance to 4 (mild clumsiness were recruited. Nine healthy participant with a SIAS score of 5 (normal also participated. Participants were asked to grasp a plastic glass and repetitively move it from the lap to the mouth and back at a conformable speed for 30 s, during which the hand movement was measured using OPTOTRAK. The position data was numerically differentiated and the three-dimensional curvature was computed. To compare against a previously proposed measure, the mean squared jerk normalized by its minimum value was computed. Age-matched healthy participants were instructed to move the glass at three different movement speeds. Results There was an inverse relationship between the curvature of the movement trajectory and the patient's SIAS score. The median of the -log of curvature (MedianLC correlated well with the SIAS score, upper extremity subsection of Fugl-Meyer Assessment, and the jerk measure in the paretic arm. When the healthy participants moved slowly, the increase in the jerk measure was comparable to the paretic movements with a SIAS score of 2 to 4, while the MedianLC was distinguishable

Putting social impact assessment to the test as a method for implementing responsible tourism practice

International Nuclear Information System (INIS)

McCombes, Lucy; Vanclay, Frank; Evers, Yvette

2015-01-01

The discourse on the social impacts of tourism needs to shift from the current descriptive critique of tourism to considering what can be done in actual practice to embed the management of tourism's social impacts into the existing planning, product development and operational processes of tourism businesses. A pragmatic approach for designing research methodologies, social management systems and initial actions, which is shaped by the real world operational constraints and existing systems used in the tourism industry, is needed. Our pilot study with a small Bulgarian travel company put social impact assessment (SIA) to the test to see if it could provide this desired approach and assist in implementing responsible tourism development practice, especially in small tourism businesses. Our findings showed that our adapted SIA method has value as a practical method for embedding a responsible tourism approach. While there were some challenges, SIA proved to be effective in assisting the staff of our test case tourism business to better understand their social impacts on their local communities and to identify actions to take. - Highlights: • Pragmatic approach is needed for the responsible management of social impacts of tourism. • Our adapted Social impact Assessment (SIA) method has value as a practical method. • SIA can be embedded into tourism businesses existing ‘ways of doing things’. • We identified challenges and ways to improve our method to better suit small tourism business context

Putting social impact assessment to the test as a method for implementing responsible tourism practice

Energy Technology Data Exchange (ETDEWEB)

McCombes, Lucy, E-mail: l.mccombes@leedsbeckett.ac.uk [International Centre for Research in Events, Tourism and Hospitality (ICRETH), Leeds Beckett University, Headingley Campus, Macaulay Hall 103, Leeds LS6 3QS (United Kingdom); Vanclay, Frank, E-mail: frank.vanclay@rug.nl [Professor of Cultural Geography, Faculty of Spatial Sciences, University of Groningen, PO Box 800, 9700AV Groningen (Netherlands); Evers, Yvette, E-mail: y.evers@tft-earth.org [The Forest Trust, Chemin de Chantavril 2, 1260 Nyon (Switzerland)

2015-11-15

The discourse on the social impacts of tourism needs to shift from the current descriptive critique of tourism to considering what can be done in actual practice to embed the management of tourism's social impacts into the existing planning, product development and operational processes of tourism businesses. A pragmatic approach for designing research methodologies, social management systems and initial actions, which is shaped by the real world operational constraints and existing systems used in the tourism industry, is needed. Our pilot study with a small Bulgarian travel company put social impact assessment (SIA) to the test to see if it could provide this desired approach and assist in implementing responsible tourism development practice, especially in small tourism businesses. Our findings showed that our adapted SIA method has value as a practical method for embedding a responsible tourism approach. While there were some challenges, SIA proved to be effective in assisting the staff of our test case tourism business to better understand their social impacts on their local communities and to identify actions to take. - Highlights: • Pragmatic approach is needed for the responsible management of social impacts of tourism. • Our adapted Social impact Assessment (SIA) method has value as a practical method. • SIA can be embedded into tourism businesses existing ‘ways of doing things’. • We identified challenges and ways to improve our method to better suit small tourism business context.

Surgically induced astigmatism after phacoemulsification with and without correction for posture-related ocular cyclotorsion: randomized controlled study.

LENUS (Irish Health Repository)

Dooley, Ian

2012-02-01

PURPOSE: To report the impact of posture-related ocular cyclotorsion on one surgeon\\'s surgically induced astigmatism (SIA) results and the variance in SIA. SETTING: Institute of Eye Surgery, Whitfield Clinic, Waterford, Ireland. METHODS: This prospective randomized controlled study included eyes that had phacoemulsification with intraocular lens implantation. Eyes were randomly assigned to have (intervention group) or not have (control group) correction for posture-related ocular cyclotorsion. In the intervention group, the clear corneal incision was placed precisely at the 120-degree meridian with instruments designed to correct posture-related ocular cyclotorsion. In the control group, the surgeon endeavored to place the incision at the 120-degree meridian, but without markings. RESULTS: The intervention group comprised 41 eyes and the control group, 61 eyes. The mean absolute SIA was 0.74 diopters (D) in the intervention group and 0.78 D in the control group; the difference between groups was not statistically significant (P>.5, unpaired 2-tailed Student t test). The variance in SIA was 0.29 D(2) and 0.31 D(2), respectively; the difference between groups was not statistically significant (P>.5, unpaired F test). CONCLUSIONS: Attempts to correct for posture-related ocular cyclotorsion did not influence SIA or its variance in a single-surgeon series. These results should be interpreted with full appreciation of the limitations of currently available techniques to correct for posture-related ocular cyclotorsion in the clinical setting.

Task analysis and computer aid development for human reliability analysis in nuclear power plants

Energy Technology Data Exchange (ETDEWEB)

Yoon, W. C.; Kim, H.; Park, H. S.; Choi, H. H.; Moon, J. M.; Heo, J. Y.; Ham, D. H.; Lee, K. K.; Han, B. T. [Korea Advanced Institute of Science and Technology, Taejeon (Korea)

2001-04-01

Importance of human reliability analysis (HRA) that predicts the error's occurrence possibility in a quantitative and qualitative manners is gradually increased by human errors' effects on the system's safety. HRA needs a task analysis as a virtue step, but extant task analysis techniques have the problem that a collection of information about the situation, which the human error occurs, depends entirely on HRA analyzers. The problem makes results of the task analysis inconsistent and unreliable. To complement such problem, KAERI developed the structural information analysis (SIA) that helps to analyze task's structure and situations systematically. In this study, the SIA method was evaluated by HRA experts, and a prototype computerized supporting system named CASIA (Computer Aid for SIA) was developed for the purpose of supporting to perform HRA using the SIA method. Additionally, through applying the SIA method to emergency operating procedures, we derived generic task types used in emergency and accumulated the analysis results in the database of the CASIA. The CASIA is expected to help HRA analyzers perform the analysis more easily and consistently. If more analyses will be performed and more data will be accumulated to the CASIA's database, HRA analyzers can share freely and spread smoothly his or her analysis experiences, and there by the quality of the HRA analysis will be improved. 35 refs., 38 figs., 25 tabs. (Author)

Fatores associados à amnésia pós-traumática de longa duração Fatores asociados a la amnesia post-traumática de larga duración Factors associated with long-term post-traumatic amnesia

Directory of Open Access Journals (Sweden)

Silvia Cristina Fürbringer e Silva

2011-01-01

Full Text Available OBJETIVO: Identificar fatores relacionados à amnésia pós-traumática de longa duração. MÉTODO: Estudo prospectivo, longitudinal, com 187 vítimas de trauma cranioencefálico contuso, idade >14 anos, atendidos em hospital de referência para trauma. As variáveis independentes foram: idade, sexo, gravidade do trauma cranioencefálico, local e tipo de lesão, número de lesões encefálicas e uso de medicação com atividade em sistema nervoso central ou corticoides. RESULTADO: O modelo de regressão logística múltipla ajustado pela variável área de lesão (intra/extra axial evidenciou: Escala de Coma de Glasgow inicial 3 (OR=2,80 e uso de Fenitoína (OR=2,60, Midazolan (OR=2,83 ou ambas as drogas (OR=3,83. CONCLUSÃO: O uso do Midazolan e da Fenitoína, além da gravidade do trauma cranioencefálico, destacaram-se como fatores relacionados à amnésia de longa duração.OBJETIVO: Identificar factores relacionados a la amnesia post-traumática de larga duración. MÉTODO: Estudio prospectivo, longitudinal, realizado con 187 víctimas de trauma craneoencefálico contuso, edad >14 años, atendidos en un hospital de referencia para trauma. Las variables independientes fueron: edad, sexo, gravedad del trauma craneoencefálico, local y tipo de lesión, número de lesiones encefálicas y uso de medicación con actividad en el sistema nervioso central o corticoides. RESULTADO: El modelo de regresión logística múltiple ajustado por la variable área de lesión (intra/extra axial evidenció: Escala de Coma de Glasgow inicial 3 (OR=2,80 y uso de Fenitoína (OR=2,60, Midazolan (OR=2,83 o ambas drogas (OR=3,83. CONCLUSIÓN: El uso del Midazolan y de Fenitoína, además de la gravedad del trauma craneoencefálico, se destacaron como factores relacionados a la amnesia de larga duración.OBJECTIVE: To identify factors related to post-traumatic amnesia of long duration. METHOD: A prospective, longitudinal study, with 187 victims of blunt head trauma

Système d'information agricole dans la vallée de Huaral, au Pérou ...

International Development Research Centre (IDRC) Digital Library (Canada)

Evaluación del componente "Investigación aplicativa" del proyecto "Sistema de Información Agraria - SIA, a favor de los Pequeños Agricultores del Valle de Huaral" : el uso de "smartphones" en el medio rural como herramienta para el acceso a la... Téléchargez le PDF. Rapports. Sistema de información agraria : SIA del ...

Self-interstitial configuration in molybdenum studied by modified ...

Indian Academy of Sciences (India)

The negative values refer a motion along negative direction of axis. It is noted that the displacements of NN atoms to a SIA are very large compared to those to a vacancy in ref. [1]. This is because adding a SIA into normal matrix will result in a large decrease in interatomic distance and thus a large increase in the acting ...

Carbon-13 conundrums: limitations and cautions in the use of stable isotope analysis in stream ecotonal research

International Nuclear Information System (INIS)

France, R.L.

1996-01-01

A secondary analysis of literature was compiled and performed on the δ 13 C values for allochthonous litter, attached algae and consumers in stream ecosystems, finding that 'existing data conflict as to the capability of stable isotope analysis (SIA) for distinguishing carbon pathways'. The paper is in defence of the work previously performed and suggests caution when using stream SIA research. 48 refs

A “novel site”: Carmen Covito, writing, literature and technology ...

African Journals Online (AJOL)

L'Internet cambia l'idea del libro e pone allo scrittore nuovi orizzonti di lettori prima impensabili. Carmen Covito è fra i primi scrittori italiani ad avere un proprio sito web. Le sue varie iniziative in internet hanno destato l'attenzione sia di critici culturali e letterari sia del grande pubblico. Tramite l'analisi di alcuni scritti di Covito ...

Et karu müttaks ja hunt uluks / Kalev Aun

Index Scriptorium Estoniae

Aun, Kalev, 1951-

2004-01-01

Keskkonnainvesteeringute Keskuse jahinduse programmi raames toetab KIK jahimaade korralduse ja ulukikaitse projekte ning jahiulukite rakendusuuringuid, trükiste väljaandmist ja jahimeeste erialast väljaõpet

Tööandja turundus - mis see on? / Kaisa-Triin Karu

Index Scriptorium Estoniae

Karu, Kaisa-Triin

2015-01-01

Business to employee marketing - turundus suunaga ettevõttelt töötajale. Tööandja turunduse eesmärk on muuta ettevõte nii potentsiaalsete kui ka olemasolevate töötajate seas atraktiivseks, kujundada tugev tööandja bränd, luua töötaja väärtuspakkumine, värbamisturunduse rakendamine

Aspects of microstructure evolution under cascade damage conditions

International Nuclear Information System (INIS)

Singh, B.N.; Trinkaus, H.; Barashev, A.V.

1997-01-01

The conventional theoretical models describing the damage accumulation, particularly void swelling, under cascade damage conditions do not include treatments of important features such as intracascade clustering of self-interstitial atoms (SIAs) and one-dimensional glide of SIA clusters produced in the cascades. Recently, it has been suggested that the problem can be treated in terms of 'production bias' and one-dimensional glide of small SIA clusters. In the earlier treatments a 'mean size approximation' was used for the defect clusters and cavities evolving during irradiation. In the present work, we use the 'size distribution function' to determine the dose dependence of sink strengths, vacancy supersaturation and void swelling as a function of dislocation density and grain size within the framework of production bias model and glide of small SIA clusters. In this work, the role of the sessile-glissile loop transformation (due to vacancy supersaturation) on the damage accumulation behaviour is included. The calculated results on void swelling are compared with the experimental results as well as the results of the earlier calculations using the 'mean size approximation'. The calculated results agree very well with the experimental results. (orig.)

A framework for combining social impact assessment and risk assessment

Energy Technology Data Exchange (ETDEWEB)

Mahmoudi, Hossein, E-mail: mahmoudi@uni-hohenheim.de [Department of Social Sciences in Agriculture, University of Hohenheim (Germany); Environmental Sciences Research Institute, Shahid Beheshti University, G.C. (Iran, Islamic Republic of); Renn, Ortwin [Department of Technology and Environmental Sociology (and DIALOGIK), University of Stuttgart (Germany); Vanclay, Frank [Department of Cultural Geography, Faculty of Spatial Sciences, University of Groningen, Groningen (Netherlands); Hoffmann, Volker [Department of Social Sciences in Agriculture, University of Hohenheim (Germany); Karami, Ezatollah [College of Agriculture, Shiraz University, Shiraz (Iran, Islamic Republic of)

2013-11-15

An increasing focus on integrative approaches is one of the current trends in impact assessment. There is potential to combine impact assessment with various other forms of assessment, such as risk assessment, to make impact assessment and the management of social risks more effective. We identify the common features of social impact assessment (SIA) and social risk assessment (SRA), and discuss the merits of a combined approach. A hybrid model combining SIA and SRA to form a new approach called, ‘risk and social impact assessment’ (RSIA) is introduced. RSIA expands the capacity of SIA to evaluate and manage the social impacts of risky projects such as nuclear energy as well as natural hazards and disasters such as droughts and floods. We outline the three stages of RSIA, namely: impact identification, impact assessment, and impact management. -- Highlights: • A hybrid model to combine SIA and SRA namely RSIA is proposed. • RSIA can provide the proper mechanism to assess social impacts of natural hazards. • RSIA can play the role of ex-post as well as ex-ante assessment. • For some complicated and sensitive cases like nuclear energy, conducting a RSIA is necessary.

Pipeline integrity management in an urban environment supported by an External Corrosion Direct Assessment (ECDA) application

Energy Technology Data Exchange (ETDEWEB)

Dus, Pedro Luiz; Valente, Antonio Carlos Rodrigues [Companhia de Gas de Sao Paulo (COMGAS), Sao Paulo, SP (Brazil); Valdes, Alberto [GE Oil and Gas-PII Pipeline Solutions, Houston, TX (United States)

2009-07-01

COMGAS is the largest natural gas distributing company in Brazil, having more than 700,000 costumers. Gas delivery to this customer base is achieved through a network of high-pressure steel pipelines (17 and 35 bar) with around 1,100 km (690 miles) in length, the majority operating inside urban areas. The Integrity Management of this network is a particularly difficult task since neither pigging nor hydrostatic testing can be used to inspect the existing pipelines. Direct Assessment (DA) is the only assessment technique available at the moment. As an initial stage COMGAS has implemented an innovative project called SIA (Sistema de Integridade de Ativos). SIA combines functionality targeted for guiding and implementing an External Corrosion Assessment (ECDA) procedure, with full data alignment and integration, corporate policies on safety and dedicated reporting capabilities. Seamless interaction between SIA and the existing Operations GIS system was a key specification requirement for the construction of the system. This paper describes the lessons learned during the implementation of the ECDA module of the SIA, the first application experiences of the ECDA process with the support of the module and the initial benefits obtained from the use of the new Integrity Management System. (author)

A framework for combining social impact assessment and risk assessment

International Nuclear Information System (INIS)

Mahmoudi, Hossein; Renn, Ortwin; Vanclay, Frank; Hoffmann, Volker; Karami, Ezatollah

2013-01-01

An increasing focus on integrative approaches is one of the current trends in impact assessment. There is potential to combine impact assessment with various other forms of assessment, such as risk assessment, to make impact assessment and the management of social risks more effective. We identify the common features of social impact assessment (SIA) and social risk assessment (SRA), and discuss the merits of a combined approach. A hybrid model combining SIA and SRA to form a new approach called, ‘risk and social impact assessment’ (RSIA) is introduced. RSIA expands the capacity of SIA to evaluate and manage the social impacts of risky projects such as nuclear energy as well as natural hazards and disasters such as droughts and floods. We outline the three stages of RSIA, namely: impact identification, impact assessment, and impact management. -- Highlights: • A hybrid model to combine SIA and SRA namely RSIA is proposed. • RSIA can provide the proper mechanism to assess social impacts of natural hazards. • RSIA can play the role of ex-post as well as ex-ante assessment. • For some complicated and sensitive cases like nuclear energy, conducting a RSIA is necessary

Parental perceptions surrounding polio and self-reported non-participation in polio supplementary immunization activities in Karachi, Pakistan: a mixed methods study.

Science.gov (United States)

Khowaja, Asif Raza; Khan, Sher Ali; Nizam, Naveeda; Omer, Saad Bin; Zaidi, Anita

2012-11-01

To assess parent's knowledge and perceptions surrounding polio and polio vaccination, self-reported participation in polio supplementary immunization activities (SIAs) targeting children aged questionnaire was administered to assess parental knowledge of polio and participation in polio SIAs conducted in September and October 2011. Additionally, 30 parents of Pashtun ethnicity (a high-risk group) who refused to vaccinate their children were interviewed in depth to determine why. Descriptive and bivariate analyses by ethnic and socioeconomic group were performed for quantitative data; thematic analysis was conducted for qualitative interviews with Pashtun parents. Of 1017 parents surveyed, 412 (41%) had never heard of polio; 132 (13%) did not participate in one SIA and 157 (15.4%) did not participate in either SIA. Among non-participants, 34 (21.6%) reported not having been contacted by a vaccinator; 116 (73.9%) reported having refused to participate, and 7 (4.5%) reported that the child was absent from home when the vaccinator visited. Refusals clustered in low-income Pashtun (43/441; 9.8%) and high-income families of any ethnic background (71/153; 46.4%). Low-income Pashtuns were more likely to not have participated in polio SIAs than low-income non-Pashtuns (odds ratio, OR: 7.1; 95% confidence interval, CI: 3.47-14.5). Reasons commonly cited among Pashtuns for refusing vaccination included fear of sterility; lack of faith in the polio vaccine; scepticism about the vaccination programme, and fear that the vaccine might contain religiously forbidden ingredients. In Karachi, interruption of polio transmission requires integrated and participatory community interventions targeting high-risk populations.

Development of a Sequential Injection Analysis System for the Determination of Saccharin.

Science.gov (United States)

Wibowotomo, Budi; Eun, Jong-Bang; Rhee, Jong Il

2017-12-12

Saccharin is a powerfully sweet nonnutritive sweetener that has been approved for food-processing applications within the range of 100-1200 mg/kg. A simple, rapid, and cost-effective sequential injection analysis (SIA) technique was developed to determine the saccharin level. This method is based on the reaction of saccharin with p-chloranil in an ethanol medium with a hydrogen peroxide (H₂O₂) acceleration, and the resultant violet-red compound was detected using a UV-Vis spectrophotometer at λ max = 420 nm. To ascertain the optimal conditions for the SIA system, several parameters were investigated, including buffer flow rate and volume, p-chloranil concentration, and reactant volumes (saccharin, p-chloranil, and H₂O₂). The optimum setup of the SIA system was achieved with a buffer flow rate, buffer volume, and draw-up time of 1.2 mL/min, 2900 µL, and ~145 s, respectively. The optimal p-chloranil concentration is 30 mM, and the best reactant volumes, presented in an ordered sequence, are as follows: 30 µL of H₂O₂, 450 µL of saccharin, and 150 µL of p-chloranil. The optimized SIA configuration produced a good linear calibration curve with a correlation coefficient (R² = 0.9812) in the concentration range of 20-140 mg/L and with a detection limit of 19.69 mg/L. Analytical applications in different food categories also showed acceptable recovery values in the range of 93.1-111.5%. This simple and rapid SIA system offers great feasibility for the saccharin quality control in food-product processing.

Quantifying the impact of expanded age group campaigns for polio eradication.

Science.gov (United States)

Wagner, Bradley G; Behrend, Matthew R; Klein, Daniel J; Upfill-Brown, Alexander M; Eckhoff, Philip A; Hu, Hao

2014-01-01

A priority of the Global Polio Eradication Initiative (GPEI) 2013-2018 strategic plan is to evaluate the potential impact on polio eradication resulting from expanding one or more Supplementary Immunization Activities (SIAs) to children beyond age five-years in polio endemic countries. It has been hypothesized that such expanded age group (EAG) campaigns could accelerate polio eradication by eliminating immunity gaps in older children that may have resulted from past periods of low vaccination coverage. Using an individual-based mathematical model, we quantified the impact of EAG campaigns in terms of probability of elimination, reduction in polio transmission and age stratified immunity levels. The model was specifically calibrated to seroprevalence data from a polio-endemic region: Zaria, Nigeria. We compared the impact of EAG campaigns, which depend only on age, to more targeted interventions which focus on reaching missed populations. We found that EAG campaigns would not significantly improve prospects for polio eradication; the probability of elimination increased by 8% (from 24% at baseline to 32%) when expanding three annual SIAs to 5-14 year old children and by 18% when expanding all six annual SIAs. In contrast, expanding only two of the annual SIAs to target hard-to-reach populations at modest vaccination coverage-representing less than one tenth of additional vaccinations required for the six SIA EAG scenario-increased the probability of elimination by 55%. Implementation of EAG campaigns in polio endemic regions would not improve prospects for eradication. In endemic areas, vaccination campaigns which do not target missed populations will not benefit polio eradication efforts.

Stability of concentration-related self-interstitial atoms in fusion material tungsten

Science.gov (United States)

Hong, Zhang; Shu-Long, Wen; Min, Pan; Zheng, Huang; Yong, Zhao; Xiang, Liu; Ji-Ming, Chen

2016-05-01

Based on the density functional theory, we calculated the structures of the two main possible self-interstitial atoms (SIAs) as well as the migration energy of tungsten (W) atoms. It was found that the difference of the and formation energies is 0.05-0.3 eV. Further analysis indicated that the stability of SIAs is closely related to the concentration of the defect. When the concentration of the point defect is high, SIAs are more likely to exist, SIAs are the opposite. In addition, the vacancy migration probability and self-recovery zones for these SIAs were researched by making a detailed comparison. The calculation provided a new viewpoint about the stability of point defects for self-interstitial configurations and would benefit the understanding of the control mechanism of defect behavior for this novel fusion material. Project supported by the Fundamental Research Funds for the Central Universities of Ministry of Education of China (Grant Nos. A0920502051411-5 and 2682014ZT30), the Program of International Science and Technology Cooperation, China (Grant No. 2013DFA51050), the National Magnetic Confinement Fusion Science Program, China (Grant Nos. 2011GB112001 and 2013GB110001), the National High Technology Research and Development Program of China (Grant No. 2014AA032701), the National Natural Science Foundation of China (Grant No. 11405138), the Southwestern Institute of Physics Funds, China, the Western Superconducting Technologies Company Limited, China, the Qingmiao Plan of Southwest Jiaotong University, China (Grant No. A0920502051517-6), and the China Postdoctoral Science Foundation (Grant No. 2014M560813).

Effect of surgical skill on surgically-induced astigmatism in cataract surgery

Directory of Open Access Journals (Sweden)

Numan Eraslan

2015-12-01

Full Text Available AIM:To evaluate the effect of surgical experience on surgically-induced astigmatism(SIAin patients with uncomplicated phacoemulsification surgery.METHODS:Fifty-three eyes of fifty patients, mean age 64.5±10.8y, were randomly divided into two groups(23 eyes and 30 eyes. First group was underwent surgery by cataract specialists and the second was by residents. At baseline all the patients were underwent a complete opthalmological examination including keratometry and autorefractometer measurements. Vector analysis programme including the Alpins' method was used for the calculation of SIA. All the measurements were repeated postoperative first day, first month and second month and changes were recorded. Shapiro Wilk and Mann-Whitney tests were applied for determining the statistical differences between the SIA with two groups.RESULTS:There were no significant differences in demographic data of the groups. Intergroup analysis showed, first group was more effective results in SIA postoperative first day(P=0.002, first month(P=0.004and the second month(P=0.001. For the first group, SIA were 0.79±0.41 diopter(Dat the first postoperative day, 0.54±0.41 D at the first postoperative month and 0.47±0.37 D at the second postoperative month. Second one was 1.27±0.66 D, 0.98±0.56 D and 0.94±0.54 D, respectively.CONCLUSION:According to the results, surgical experience was one of the factors that affects SIA. Residents would perform more phacoemilcification surgery to obtain more surgical experience.

Composizione e dinamiche della microflora in differenti ecosistemi caseari

OpenAIRE

Santarelli, Marcela

2012-01-01

Il formaggio è un cibo biologicamente e biochimicamente dinamico contenente microorganismi sia intenzionalmente aggiunti come colture starter sia presenti come contaminanti avventizi di natura non-starter. La composizione della popolazione microbica si modifica sotto l’influenza di continui cambiamenti delle condizioni ambientali e delle interazioni tra i microorganismi durante la produzione e la stagionatura. Nel processo produttivo del formaggio, la selezione di parametri tecnologici pu...

Secondary Inorganic Aerosols over an Urban Location in North-Western Himalayan Region: Seasonal Variation in Composition and Formation Process(es)

Science.gov (United States)

Kaushal, D.; Tandon, A.

2017-12-01

Oxidative photo-chemical transformation of precursor gases, mainly of anthropogenic origin, produces secondary aerosols. Secondary inorganic aerosols constitute a significant fraction of total aerosol load over urban locations especially high altitude in wet-temperate climatic set-up. Towns situated in North-Western Himalayan region (NWHR) with sizable population and attractive tourist destinations have been facing ever increasing problem of gaseous and particulate air pollution from exponential increase in vehicular traffic and other anthropogenic emissions. The present study has been planned to investigate the seasonal variations in atmospheric processes responsible for the formation of Secondary Inorganic Aerosols (SIA) and to estimate contribution of SIA to PM­10 load over an Urban location, Dharamshala, in Dhauladhar region of NWHR. Twenty four hourly PM10 aerosol samples were collected, on quartz micro fibre filters in Dharamshala (1350 amsl) on weekly basis for complete one year time-period (February 2015 - January 2016). These samples were analyzed for Water Soluble Inorganic Ions (WSII) using Ion-Chromatographic System. On annual basis, SO42- ions contributed maximum (52%) followed by NO3- (13%) and NH4+ (12%) to WSII. Based upon Principal Component Analysis (PCA), dominant sources contributing to PM10 associated WSII were identified as: Fossil-Fuel and Bio-mass burning, Vehicular (mainly diesel) emissions and gaseous emissions from the microbial degradation of dead bio-mass. Throughout the year, significantly high proportion of SO42- and considerable thermodynamic stability of (NH4)2SO2 at ambient temperatures, made it the major contributor to SIA over NH4NO3 and NH4Cl. On seasonal basis, maximum contribution of SIA to PM10 was observed in monsoon followed by the winter season. Low ambient temperature in winter season favoured formation of NH4NO3 with significant contribution to SIA. It could be concluded that observed variability in the composition and

Source apportionment of PM2.5 in North India using source-oriented air quality models

International Nuclear Information System (INIS)

Guo, Hao; Kota, Sri Harsha; Sahu, Shovan Kumar; Hu, Jianlin; Ying, Qi; Gao, Aifang; Zhang, Hongliang

2017-01-01

In recent years, severe pollution events were observed frequently in India especially at its capital, New Delhi. However, limited studies have been conducted to understand the sources to high pollutant concentrations for designing effective control strategies. In this work, source-oriented versions of the Community Multi-scale Air Quality (CMAQ) model with Emissions Database for Global Atmospheric Research (EDGAR) were applied to quantify the contributions of eight source types (energy, industry, residential, on-road, off-road, agriculture, open burning and dust) to fine particulate matter (PM 2.5 ) and its components including primary PM (PPM) and secondary inorganic aerosol (SIA) i.e. sulfate, nitrate and ammonium ions, in Delhi and three surrounding cities, Chandigarh, Lucknow and Jaipur in 2015. PPM mass is dominated by industry and residential activities (>60%). Energy (∼39%) and industry (∼45%) sectors contribute significantly to PPM at south of Delhi, which reach a maximum of 200 μg/m 3 during winter. Unlike PPM, SIA concentrations from different sources are more heterogeneous. High SIA concentrations (∼25 μg/m 3 ) at south Delhi and central Uttar Pradesh were mainly attributed to energy, industry and residential sectors. Agriculture is more important for SIA than PPM and contributions of on-road and open burning to SIA are also higher than to PPM. Residential sector contributes highest to total PM 2.5 (∼80 μg/m 3 ), followed by industry (∼70 μg/m 3 ) in North India. Energy and agriculture contribute ∼25 μg/m 3 and ∼16 μg/m 3 to total PM 2.5 , while SOA contributes <5 μg/m 3 . In Delhi, industry and residential activities contribute to 80% of total PM 2.5 . - Highlights: • Sources of PM 2.5 in North India were quantified by source-oriented CMAQ. • Industrial/residential activities are the dominating sources (60–70%) for PPM. • Energy/agriculture are the most important sources (30–40%) for SIA. • Strong seasonal

HT_BIM: La modellazione parametrica per l’analisi del rischio nei centri storici

Directory of Open Access Journals (Sweden)

Assunta Pelliccio

2017-06-01

Full Text Available I centri storici minori sono dei monumenti d’ambiente da salvaguardare perché vulnerabili sia dal punto di vista sismico che ambientale. La gestione di queste realtà urbane è particolarmente complessa a causa dell’eterogeneità dei dati relativi alle singole unità edilizie, aggregati strutturali e intero ambito urbano. Negli ultimi anni i sistemi parametrici BIM hanno dato un enorme contributo alla progettazione, pianificazione, costruzione etc. di nuovi edifici e anche alla gestione del patrimonio culturale. L’obiettivo di questo lavoro è lo sviluppo del sistema Historical Town Building Information Modeling (HT_BIM, ovvero di un sistema BIM specifico per gli aggregati di edifici storici che, sulla base del rilievo, consente di individuare vulnerabilità legate sia ad aspetti strutturali sia a fenomeni di degrado da vento e soleggiamento.

Isa-ema maa : [luuletused] / Leelo Tungal

Index Scriptorium Estoniae

Tungal, Leelo, 1947-

2001-01-01

Sisu: Isa-ema maa ; Vahetund ; Päkapikk võis näha ; Kodune jutt ; Koeruse mõõt ; mütsid ; Loomade laul ; Igal sügisel ; Väike jõulusoov ; Millal tuled, jõuluvana ; Paharet ; Suur õun ; Teiste laste mänguasjad ; Oi heldeke! ; Tere-tere ; Kui ma ... ; Magus tähestik ; Pluss ja miinus ; Pinalis ; Esimese klassi õpilane ; Teise klassi õpilane ; Miks on kana vana? ; Hommik ; Seitsme maa ja mere taga ; Köha pere ; Harjad ; Täna sügist mängib suvi ; Toas ; Laps jäi voodis magama ; Klassivennad ; Talvehommik ; Siili elu ; Hiirehernesupp ; Hundi lugemine ; Karu ärkamine ; Unelaul ; Salajutt ; Kooli eel ; Laiskvorsti elu ; Kindel plaan ; Oma kohal ; Puhkama ; Vana vahva lasteaed ; Sama laps ; Tüli

Epidemiologia molecolare di Listeria monocytogenes per l'implementazione della sorveglianza e della valutazione del rischio infettivo

OpenAIRE

Tamburro, Manuela

2010-01-01

Listeria monocytogenes è un patogeno umano a trasmissione alimentare, ampiamente distribuito nell’ambiente, che causa la listeriosi, un importante problema per la Sanità Pubblica per l’elevato tasso di letalità (20-30%). Sia i casi sporadici sia quelli epidemici sono soprattutto associati al consumo di alimenti contaminati. Le manifestazioni cliniche vanno da gastroenteriti febbrili fino a forme invasive negli individui suscettibili (immunocompromessi, anziani, donne in gravidanza e neonati),...

Antropologia multidisciplinare o multiantropologia indisciplinata?

OpenAIRE

Emiliano Bruner

2008-01-01

Il flusso di informazioni attualmente disponibili crea evidenti sovraccarichi sia nell’organizzazione personale della conoscenza sia nell’integrazione tra discipline differenti. La multidisciplinarietà viene a gran voce acclamata e reclamata come soluzione da un lato a una ingestibile produzione di nozioni, dall’altro ad una certa stanchezza culturale di molte discipline in stasi preoccupante. A fronte di questa comune esigenza policulturale, gli esempi di riuscite integrazioni professionali ...

Strategie della conoscenza nella riflessione di Guglielmo di S. ThierryAmor incapibilem capit, incomprehensibilem comprehendit

OpenAIRE

Rossini, Marco

2008-01-01

Il problema della visio Dei: si intende comprendere cosa Dio sia, non chi sia. Fondamentale è l'analogia con la struttura della conoscenza sensibile, caratterizzata dall'identificazione fra soggetto conoscente e oggetto conosciuto. L'amore, inteso come sensus animae, opera per mezzo di una conoscenza identificante attraverso una modificazione del sentimento, anche se con una fondamentale differenza rispetto agli altri sensi, in quanto essenzialmente caratterizzato dalla libertà. La declinazio...

Development of a Sequential Injection Analysis System for the Determination of Saccharin

Directory of Open Access Journals (Sweden)

Budi Wibowotomo

2017-12-01

Full Text Available Saccharin is a powerfully sweet nonnutritive sweetener that has been approved for food-processing applications within the range of 100–1200 mg/kg. A simple, rapid, and cost-effective sequential injection analysis (SIA technique was developed to determine the saccharin level. This method is based on the reaction of saccharin with p-chloranil in an ethanol medium with a hydrogen peroxide (H2O2 acceleration, and the resultant violet-red compound was detected using a UV-Vis spectrophotometer at λmax = 420 nm. To ascertain the optimal conditions for the SIA system, several parameters were investigated, including buffer flow rate and volume, p-chloranil concentration, and reactant volumes (saccharin, p-chloranil, and H2O2. The optimum setup of the SIA system was achieved with a buffer flow rate, buffer volume, and draw-up time of 1.2 mL/min, 2900 µL, and ~145 s, respectively. The optimal p-chloranil concentration is 30 mM, and the best reactant volumes, presented in an ordered sequence, are as follows: 30 µL of H2O2, 450 µL of saccharin, and 150 µL of p-chloranil. The optimized SIA configuration produced a good linear calibration curve with a correlation coefficient (R2 = 0.9812 in the concentration range of 20–140 mg/L and with a detection limit of 19.69 mg/L. Analytical applications in different food categories also showed acceptable recovery values in the range of 93.1–111.5%. This simple and rapid SIA system offers great feasibility for the saccharin quality control in food-product processing.

Displacement cascades and defects annealing in tungsten, Part I: Defect database from molecular dynamics simulations

Energy Technology Data Exchange (ETDEWEB)

Setyawan, Wahyu [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Nandipati, Giridhar [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Roche, Kenneth J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Univ. of Washington, Seattle, WA (United States); Heinisch, Howard L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wirth, Brian D. [Univ. of Tennessee, Knoxville, TN (United States); Oak Ridge National Lab., Oak Ridge, TN (United States); Kurtz, Richard J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2015-07-01

Molecular dynamics simulations have been used to generate a comprehensive database of surviving defects due to displacement cascades in bulk tungsten. Twenty-one data points of primary knock-on atom (PKA) energies ranging from 100 eV (sub-threshold energy) to 100 keV (~780^×_Ed, where _Ed = 128 eV is the average displacement threshold energy) have been completed at 300 K, 1025 K and 2050 K. Within this range of PKA energies, two regimes of power-law energy-dependence of the defect production are observed. A distinct power-law exponent characterizes the number of Frenkel pairs produced within each regime. The two regimes intersect at a transition energy which occurs at approximately 250^×_Ed. The transition energy also marks the onset of the formation of large self-interstitial atom (SIA) clusters (size 14 or more). The observed defect clustering behavior is asymmetric, with SIA clustering increasing with temperature, while the vacancy clustering decreases. This asymmetry increases with temperature such that at 2050 K (~0.5_Tm) practically no large vacancy clusters are formed, meanwhile large SIA clusters appear in all simulations. The implication of such asymmetry on the long-term defect survival and damage accumulation is discussed. In addition, <100> {110} SIA loops are observed to form directly in the highest energy cascades, while vacancy <100> loops are observed to form at the lowest temperature and highest PKA energies, although the appearance of both the vacancy and SIA loops with Burgers vector of <100> type is relatively rare.

Comparison between beta radiation dose distribution due to LDR and HDR ocular brachytherapy applicators using GATE Monte Carlo platform.

Science.gov (United States)

Mostafa, Laoues; Rachid, Khelifi; Ahmed, Sidi Moussa

2016-08-01

Eye applicators with 90Sr/90Y and 106Ru/106Rh beta-ray sources are generally used in brachytherapy for the treatment of eye diseases as uveal melanoma. Whenever, radiation is used in treatment, dosimetry is essential. However, knowledge of the exact dose distribution is a critical decision-making to the outcome of the treatment. The Monte Carlo technique provides a powerful tool for calculation of the dose and dose distributions which helps to predict and determine the doses from different shapes of various types of eye applicators more accurately. The aim of this work consisted in using the Monte Carlo GATE platform to calculate the 3D dose distribution on a mathematical model of the human eye according to international recommendations. Mathematical models were developed for four ophthalmic applicators, two HDR 90Sr applicators SIA.20 and SIA.6, and two LDR 106Ru applicators, a concave CCB model and a flat CCB model. In present work, considering a heterogeneous eye phantom and the chosen tumor, obtained results with the use of GATE for mean doses distributions in a phantom and according to international recommendations show a discrepancy with respect to those specified by the manufacturers. The QC of dosimetric parameters shows that contrarily to the other applicators, the SIA.20 applicator is consistent with recommendations. The GATE platform show that the SIA.20 applicator present better results, namely the dose delivered to critical structures were lower compared to those obtained for the other applicators, and the SIA.6 applicator, simulated with MCNPX generates higher lens doses than those generated by GATE. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Segregation of cascade induced interstitial loops at dislocations: possible effect on initiation of plastic deformation

Energy Technology Data Exchange (ETDEWEB)

Trinkaus, H. [Forschungszentrum Juelich GmbH (Germany). Inst. fuer Festkoerperforschung; Singh, B.N. [Materials Research Department, Risoe National Laboratory, DK-4000 Roskilde (Denmark); Foreman, A.J.E. [Materials Performance Department, Harwell Laboratory, Oxfordshire OX11 0RA (United Kingdom)

1997-11-01

In metals and alloys subjected to cascade damage dislocations are frequently found to be decorated with a high density of small clusters of self-interstitial atoms (SIAs) in the form of dislocation loops. In the present paper it is shown that this effect may be attributed to the glide and trapping of SIA loops, produced directly in cascades (rather than to the enhanced agglomeration of single SIAs), in the strain field of the dislocations. The conditions for the accumulation of glissile SIA loops near dislocations as well as the dose and temperature dependencies of this phenomenon are discussed. It is suggested that the decoration of dislocations with loops may play a key role in radiation hardening subjected to cascade damage. It is shown, for example, that the increase in the upper yield stress followed by a yield drop and plastic instability in metals andalloys subjected to cascade damage cannot be rationalized in terms of conventional dispersed barrier hardening (DBH) but may be understood in terms of cascade induced source hardening (CISH) in which the dislocations are considered to be locked by the loops decorating them. Estimates for the stress necessary to pull a dislocation away from its loop `cloud` are used to discuss the dose and temperature dependence of plastic flow initiation. (orig.). 55 refs.

Segregation of cascade induced interstitial loops at dislocations: possible effect on initiation of plastic deformation

International Nuclear Information System (INIS)

Trinkaus, H.; Foreman, A.J.E.

1997-01-01

In metals and alloys subjected to cascade damage dislocations are frequently found to be decorated with a high density of small clusters of self-interstitial atoms (SIAs) in the form of dislocation loops. In the present paper it is shown that this effect may be attributed to the glide and trapping of SIA loops, produced directly in cascades (rather than to the enhanced agglomeration of single SIAs), in the strain field of the dislocations. The conditions for the accumulation of glissile SIA loops near dislocations as well as the dose and temperature dependencies of this phenomenon are discussed. It is suggested that the decoration of dislocations with loops may play a key role in radiation hardening subjected to cascade damage. It is shown, for example, that the increase in the upper yield stress followed by a yield drop and plastic instability in metals andalloys subjected to cascade damage cannot be rationalized in terms of conventional dispersed barrier hardening (DBH) but may be understood in terms of cascade induced source hardening (CISH) in which the dislocations are considered to be locked by the loops decorating them. Estimates for the stress necessary to pull a dislocation away from its loop 'cloud' are used to discuss the dose and temperature dependence of plastic flow initiation. (orig.)

Role of Interface in Multilayered Composites under Irradiation: A Mathematical Investigation

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Jaime Ortún-Palacios

2017-01-01

Full Text Available A continuum model of point-defects evolution during irradiation of a multilayer composite material is presented in this work. Nonstationary balance equations are used to describe production, recombination, transport, and annihilation, or removal, of vacancies and interstitials in a β-α-β three-layer system (α = Cu and β = Nb, V, or Ni. In addition, transport and trapping of point-defects at interfaces are taken into account. Numerical investigation on similarities and differences between Cu/Nb, Cu/V, and Cu/Ni systems is also performed. A general comparison of model results reveals that average vacancy concentration is typically higher than SIA one in both layers for all the systems investigated. This is a consequence of the higher diffusion rate of SIAs with respect to vacancies. Stationary state is reached without saturating interface point-defect traps by all systems but Cu/Ni for the case of SIAs. It can be also seen that Cu/Nb and Cu/V systems have a very similar behavior regarding point-defect temporal evolution in copper (layer α, while higher SIA concentration at steady state is shown therein by the Cu/Ni structure. Moreover, Cu/V system displays the lower stationary vacancy concentration in layer β.

First-principles investigation of the energetics of point defects at a grain boundary in tungsten

Energy Technology Data Exchange (ETDEWEB)

Chai, Jun; Li, Yu-Hao; Niu, Liang-Liang; Qin, Shi-Yao; Zhou, Hong-Bo, E-mail: hbzhou@buaa.edu.cn; Jin, Shuo; Zhang, Ying; Lu, Guang-Hong

2017-02-15

Tungsten (W) and W alloys are considered as the most promising candidates for plasma facing materials in future fusion reactor. Grain boundaries (GBs) play an important role in the self-healing of irradiation defects in W. Here, we investigate the stability of point defects [vacancy and self-interstitial atoms (SIA’s)] in a Σ5(3 1 0) [0 0 1] tilt W GB by calculating the energetics using a first-principles method. It is found that both the vacancy and SIA are energetically favorable to locate at neighboring sites of the GB, suggesting the vacancy and SIA can easily segregate to the GB region with the segregation energy of 1.53 eV and 7.5 eV, respectively. This can be attributed to the special atomic configuration and large available space of the GB. The effective interaction distance between the GB and the SIA is ∼6.19 Å, which is ∼2 Å larger than that of the vacancy-GB, indicating the SIA are more preferable to locate at the GB in comparison with the vacancy. Further, the binding energy of di-vacancies in the W GB are much larger than that in bulk W, suggesting that the vacancy energetically prefers to congregate in the GB.

Genomica avanzata per lo studio dei geni di resistenza a patogeni in pianta

OpenAIRE

Sanseverino, Walter

2009-01-01

I geni di resistenza hanno grossa importanza nel settore della genetica vegetale e del miglioramento genetico. Le loro caratteristiche genetiche e strutturali li rendono interessanti sia da un punto di vista scientifico sia nell’ottica di un loro utilizzo pratico. Sono una famiglia affascinante da studiare e capire i loro meccanismi evolutivi e di interazione con altre proteine rappresenta una sfida per il chiarimento di molte caratteristiche molecolari e di funzionamento. Questo studio propo...

Francesco Cattani – Luca Raimondi (eds.), Ombre. Quaderni di Synapsis X

OpenAIRE

Rossini, Gianluigi

2013-01-01

Arrivano alla decima uscita, con un nuovo editore, i Quaderni di Synapsis, collana che raccoglie gli atti della Scuola Europea di Letterature Comparate fondata da Roberto Bigazzi, Laura Caretti e Remo Ceserani. Il volume comprende sia alcune delle conferenze tenute da affermati studiosi nel corso della settimana dei lavori (svoltasi presso il Centro Residenziale Universitario di Bertinoro, dal 6 al 13 settembre 2009) sia una selezione dei progetti di ricerca concepiti dagli studenti a partire...

Caratterizzazione biomolecolare di Clostridi isolati da latte e formaggi

OpenAIRE

Demarco, Fabiana

2006-01-01

Il latte è una miscela complessa di sostanze di notevole importanza biologica e nutrizionale (proteime, grassi, lattosio, vitamine, sali, etc.) e costituisce, da solo un sistema dietetico bilanciato e capace di favorire la moltiplicazione della flora intestinale simbiotica. E’ ampiamente utilizzato sia tal quale nella preparazione del cibo, sia trasformato, da solo, o in combinazione con altri alimenti. Il formaggio, che rappresenta il più antico e valido metodo conosciuto dall’uomo per co...

Social impact assessment in energy projects

International Nuclear Information System (INIS)

Koivujaervi, S.; Kantola, I.; Maekinen, P.

1998-01-01

The research report is based on literature and interviews on the social impact assessment (SIA) in energy projects in Finland, both before and after the EIA Act has been in force in Finland. The concept and content of SIA, the requirements set by the legislation, its relation with other environmental impacts, the assessment process and the used methods have been studied on the basis of the literature analysis. A total of 26 persons representing the coordination authorities, persons issuing statements, researchers, civil servants, consultants and project developers were interviewed for the research. The interviews were made by the University of Turku in the form of theme interviews, investigating the present status, practices and expectations of the SIA. The unestablished status was seen to be the problem in the SIA, which was reflected in the interviewers' varying views about the content of the SIA. Among the operators, the general character of the SIA criticism in the statements concerning the assessment programmes or reports was seen as a problem as well; the assessment of social impact has been considered to be insufficient, however, without any identification of the effects or how the effects should have been assessed. For the time preceding the EIA Act, the assessment of the social impact of hydraulic work, power plant and transmission line projects and the project of the fifth nuclear power plant have been studied. As to the power plant and transmission line projects after the validity of the EIA Act, all the 20 projects were gone through which had progressed during the spring 1998 at least to the assessment report stage. Of these projects, the assessment of the social impact of one transmission line and one power plant project was studied in detail. The report also studies the assessment of the social impact of the repository for nuclear waste on the basis of the experience gained in Finland and in other countries. On the basis of the literature study

Spinal sagittal balance substantially influences locomotive syndrome and physical performance in community-living middle-aged and elderly women.

Science.gov (United States)

Muramoto, Akio; Imagama, Shiro; Ito, Zenya; Hirano, Kenichi; Ishiguro, Naoki; Hasegawa, Yukiharu

2016-03-01

Spinal sagittal imbalance has been well known risk factor of decreased quality of life in the field of adult spinal deformity. However, the impact of spinal sagittal balance on locomotive syndrome and physical performance in community-living elderly has not yet been clarified. The present study investigated the influence of spinal sagittal alignment on locomotive syndrome (LS) and physical performance in community-living middle-aged and elderly women. A total of 125 women between the age of 40-88 years (mean 66.2 ± 9.7 years) who completed the questionnaires, spinal mouse test, physical examination and physical performance tests in Yakumo study were enrolled in this study. Participants answered the 25-Question Geriatric Locomotive Function Scale (GLFS-25), the visual analog scale (VAS) for low back pain (LBP), knee pain. LS was defined as having a score of >16 points on the GLFS-25. Using spinal mouse, spinal inclination angle (SIA), thoracic kyphosis angle (TKA), lumbar lordosis angle (LLA), sacral slope angle (SSA), thoracic spinal range of motion (TSROM), lumbar spinal range of motion (LSROM) were measured. Timed-up-and-go test (TUG), one-leg standing time with eyes open (OLS), and maximum stride, back muscle strength were also measured. The relationship between spinal sagittal parameters and GLFS-25, VAS and physical performance tests were analyzed. 26 people were diagnosed as LS and 99 were diagnosed as non-LS. LBP and knee pain were greater, physical performance tests were poorer, SIA were greater, LLA were smaller in LS group compared to non-LS group even after adjustment by age. SIA significantly correlated with GLFS-25, TUG, OLS and maximum stride even after adjustment by age. The cutoff value of SIA for locomotive syndrome was 6°. People with a SIA of 6° or greater were grouped as "Inclined" and people with a SIA of less than 6° were grouped as "Non-inclined". 21 people were "Inclined" and 104 were "Non-inclined". Odds ratio to fall in LS of

IL DUELLO NEL RINASCIMENTO E IL RIPENSAMENTO ETICO SUL DUELLO DI FRANCESCO PATRIZI

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Fulvio Šuran

2012-01-01

Full Text Available In questa prima parte del saggio ci soff ermeremo in modo particolare al periodo che intercorre tra la seconda metà del XV secolo e la prima metà del XVI secolo, in quanto è in questo lasso di tempo che si trovano serie e chiare testimonianze riguardanti la questione del duello. E questo sia nelle opere letterarie che in quelle riguardanti la precettistica. Per quanto riguarda quelle di precettistica, oltre al gran numero di trattati, è da tener presente anche il gran numero delle loro riedizioni, specialmente di quelli più famosi. Dove, oltre all'immancabile comunanza d’interessi fra poeti epici e trattatisti del duello, si noterà anche una sostanziale identità terminologica - per esempio sia i poeti sia i trattatisti ritengono che il duello sia una ‘prova’ di giudizio fi nale. Questo non comporta, nel contempo, una convergenza di convinzioni fi losofi che, in quanto, come si vedrà, il duello letterario diff erisce da quello reale proprio per la sua diversa comprensione fi losofi ca del combattere. Pertanto con la presente relazione si cercherà di dispiegare la problematica che questo istituto di per sé ha comportato nel periodo storico preso in considerazione. Il duello infatti si configurava come una questione sociale tutt'altro che irrilevante per la sua connotazione ambivalente di ordalia – quale forma particolare di rapporto fra uomo e sacro – e di inculpata tutela – quale forma particolare di ricorso alla violenza privata a tutela di un fondamentale diritto naturale. In tutti e due i casi si tratta di una forma di onore, sia individuale sia nobiliare, del quale il Patrizi ne discuterà la fondatezza interpretandolo specialmente in qualità di virtù. In questa defi nizione dell'onore – che il Patrizi aff ronta con un gusto platonico – si possono scorgere questioni di alta portata politica, che ponevano sotto varia forma la questione dei rapporti tra individuo e Stato. In tal modo il duello d’onore assumeva un

Self-interstitial atoms in metals

International Nuclear Information System (INIS)

Schilling, W.

1978-01-01

The present state of knowledge and understanding of the properties of self-interstitial atoms (SIAs) in metals is reviewed. Special emphasis is given to a discussion of the structure of SIAs and those properties which relate to structure such as relaxation volumes, elastic polarizabilities, defect vibrations, geometry of jump processes, and elastic interactions. The present experimental status with respect to these properties is summarized, and the basic theoretical concepts for their understanding are presented as simply as possible. (Auth.)

Confirmatory Factor Analysis of the Combined Social Phobia Scale and Social Interaction Anxiety Scale: Support for a Bifactor Model

OpenAIRE

Gomez, Rapson; Watson, Shaun D.

2017-01-01

For the Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS) together, this study examined support for a bifactor model, and also the internal consistency reliability and external validity of the factors in this model. Participants (N = 526) were adults from the general community who completed the SPS and SIAS. Confirmatory factor analysis (CFA) of their ratings indicated good support for the bifactor model. For this model, the loadings for all but six items were higher o...

The dutch social interaction anxiety scale and the social phobia scale: reliability, validity, and clinical utility.

Science.gov (United States)

de Beurs, Edwin; Tielen, Deirdre; Wollmann, Lisa

2014-01-01

The social interaction anxiety scale (SIAS) and the social phobia scale (SPS) assess anxiety in social interactions and fear of scrutiny by others. This study examines the psychometric properties of the Dutch versions of the SIAS and SPS using data from a large group of patients with social phobia and a community-based sample. Confirmatory factor analysis revealed that the SIAS is unidimensional, whereas the SPS is comprised of three subscales. The internal consistency of the scales and subscales was good. The concurrent and discriminant validity was supported and the scales were well able to discriminate between patients and community-based respondents. Cut-off values with excellent sensitivity and specificity are presented. Of all self-report measures included, the SPS was the most sensitive for treatment effects. Normative data are provided which can be used to assess whether clinically significant change has occurred in individual patients.

The Dutch Social Interaction Anxiety Scale and the Social Phobia Scale: Reliability, Validity, and Clinical Utility

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Edwin de Beurs

2014-01-01

Full Text Available The social interaction anxiety scale (SIAS and the social phobia scale (SPS assess anxiety in social interactions and fear of scrutiny by others. This study examines the psychometric properties of the Dutch versions of the SIAS and SPS using data from a large group of patients with social phobia and a community-based sample. Confirmatory factor analysis revealed that the SIAS is unidimensional, whereas the SPS is comprised of three subscales. The internal consistency of the scales and subscales was good. The concurrent and discriminant validity was supported and the scales were well able to discriminate between patients and community-based respondents. Cut-off values with excellent sensitivity and specificity are presented. Of all self-report measures included, the SPS was the most sensitive for treatment effects. Normative data are provided which can be used to assess whether clinically significant change has occurred in individual patients.

Acidosis-mediated regulation of the NHE1 isoform of the Na⁺/H⁺ exchanger in renal cells.

Science.gov (United States)

Odunewu, Ayodeji; Fliegel, Larry

2013-08-01

The mammalian Na⁺/H⁺ exchanger isoform 1 (NHE1) is a ubiquitous plasma membrane protein that regulates intracellular pH by removing a proton in exchange for extracellular sodium. Renal tissues are subject to metabolic and respiratory acidosis, and acidosis has been shown to acutely activate NHE1 activity in other cell types. We examined if NHE1 is activated by acute acidosis in HEK293 and Madin-Darby canine kidney (MDCK) cells. Acute sustained intracellular acidosis (SIA) activated NHE1 in both cell types. We expressed wild-type and mutant NHE1 cDNAs in MDCK cells. All the cDNAs had a L163F/G174S mutation, which conferred a 100-fold resistance to EMD87580, an NHE1-specific inhibitor. We assayed exogenous NHE1 activity while inhibiting endogenous activity with EMD87580 and while inhibiting the NHE3 isoform of the Na⁺/H⁺ exchanger using the isoform-specific inhibitor S3226. We examined the activation and phosphorylation of the wild-type and mutant NHE1 proteins in response to SIA. In MDCK cells we demonstrated that the amino acids Ser⁷⁷¹, Ser⁷⁷⁶, Thr⁷⁷⁹, and Ser⁷⁸⁵ are important for NHE1 phosphorylation and activation after acute SIA. SIA activated ERK-dependent pathways in MDCK cells, and this was blocked by treatment with the MEK inhibitor U0126. Treatment with U0126 also blocked activation of NHE1 by SIA. These results suggest that acute acidosis activates NHE1 in mammalian kidney cells and that in MDCK cells this activation occurs through an ERK-dependent pathway affecting phosphorylation of a distinct set of amino acids in the cytosolic regulatory tail of NHE1.

Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.

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Shohei Ogata

Full Text Available Although intravenous immunoglobulin (IVIG is highly effective in Kawasaki disease (KD, mechanisms are not understood and 10-20% of patients are treatment-resistant, manifesting a higher rate of coronary artery aneurysms. Murine models suggest that α2-6-linked sialic acid (α2-6Sia content of IVIG is critical for suppressing inflammation. However, pro-inflammatory states also up-regulate endogenous levels of β-galactoside:α2-6 sialyltransferase-I (ST6Gal-I, the enzyme that catalyzes addition of α2-6Sias to N-glycans. We asked whether IVIG failures correlated with levels of α2-6Sia on infused IVIG or on the patient's own endogenous IgG.We quantified levels of α2-6Sia in infused IVIG and endogenous IgG from 10 IVIG-responsive and 10 resistant KD subjects using multiple approaches. Transcript levels of ST6GAL1, in patient whole blood and B cell lines were evaluated by RT-PCR. Plasma soluble (sST6Gal-I levels were measured by ELISA.There was no consistent difference in median sialylation levels of infused IVIG between groups. However, α2-6Sia levels in endogenous IgG, ST6GAL1 transcript levels, and ST6Gal-I protein in serum from IVIG-resistant KD subjects were lower than in responsive subjects at both pre-treatment and one-year time points (p <0.001, respectively.Our data indicate sialylation levels of therapeutic IVIG are unrelated to treatment response in KD. Rather, lower sialylation of endogenous IgG and lower blood levels of ST6GALI mRNA and ST6Gal-I enzyme predict therapy resistance. These differences were stable over time, suggesting a genetic basis. Because IVIG-resistance increases risk of coronary artery aneurysms, our findings have important implications for the identification and treatment of such individuals.

Blood Plasma-Derived Anti-Glycan Antibodies to Sialylated and Sulfated Glycans Identify Ovarian Cancer Patients.

Science.gov (United States)

Pochechueva, Tatiana; Chinarev, Alexander; Schoetzau, Andreas; Fedier, André; Bovin, Nicolai V; Hacker, Neville F; Jacob, Francis; Heinzelmann-Schwarz, Viola

2016-01-01

Altered levels of naturally occurring anti-glycan antibodies (AGA) circulating in human blood plasma are found in different pathologies including cancer. Here the levels of AGA directed against 22 negatively charged (sialylated and sulfated) glycans were assessed in high-grade serous ovarian cancer (HGSOC, n = 22) patients and benign controls (n = 31) using our previously developed suspension glycan array (SGA). Specifically, the ability of AGA to differentiate between controls and HGSOC, the most common and aggressive type of ovarian cancer with a poor outcome was determined. Results were compared to CA125, the commonly used ovarian cancer biomarker. AGA to seven glycans that significantly (P<0.05) differentiated between HGSOC and control were identified: AGA to top candidates SiaTn and 6-OSulfo-TF (both IgM) differentiated comparably to CA125. The area under the curve (AUC) of a panel of AGA to 5 glycans (SiaTn, 6-OSulfo-TF, 6-OSulfo-LN, SiaLea, and GM2) (0.878) was comparable to CA125 (0.864), but it markedly increased (0.985) when combined with CA125. AGA to SiaTn and 6-OSulfo-TF were also valuable predictors for HGSOC when CA125 values appeared inconclusive, i.e. were below a certain threshold. AGA-glycan binding was in some cases isotype-dependent and sensitive to glycosidic linkage switch (α2-6 vs. α2-3), to sialylation, and to sulfation of the glycans. In conclusion, plasma-derived AGA to sialylated and sulfated glycans including SiaTn and 6-OSulfo-TF detected by SGA present a valuable alternative to CA125 for differentiating controls from HGSOC patients and for predicting the likelihood of HGSOC, and may be potential HGSOC tumor markers.

Infectious Disease Risk and Vaccination in Northern Syria after 5 Years of Civil War: The MSF Experience.

Science.gov (United States)

de Lima Pereira, Alan; Southgate, Rosamund; Ahmed, Hikmet; O'Connor, Penelope; Cramond, Vanessa; Lenglet, Annick

2018-02-02

In 2015, following an influx of population into Kobanê in northern Syria, Médecins Sans Frontières (MSF) in collaboration with the Kobanê Health Administration (KHA) initiated primary healthcare activities. A vaccination coverage survey and vaccine-preventable disease (VPD) risk analysis were undertaken to clarify the VPD risk and vaccination needs. This was followed by a measles Supplementary Immunization Activity (SIA). We describe the methods and results used for this prioritisation activity around vaccination in Kobanê in 2015. We implemented a pre-SIA survey in 135 randomly-selected households in Kobanê using a vaccination history questionnaire for all children Syria. The VPD Risk Analysis prioritised measles, Haemophilus Influenza type B (Hib) and Pneumococcus vaccinations. In the measles SIA, 3410 children aged 6-59 months were vaccinated. The use of multiple small vaccination sites to reduce risks associated with crowds in this active conflict setting was noted as a lesson learnt. The post-SIA survey estimated 82% (95%CI: 76.9-85.9%; n=229/280) measles vaccination coverage in children 6-59 months. As a result of the conflict in Syria, the progressive collapse of the health care system in Kobanê has resulted in low vaccine coverage rates, particularly in younger age groups. The repeated displacements of the population, attacks on health institutions and exodus of healthcare workers, challenge the resumption of routine immunization in this conflict setting and limit the use of SIAs to ensure sustainable immunity to VPDs. We have shown that the risk for several VPDs in Kobanê remains high. We call on all health actors and the international community to work towards re-establishment of routine immunisation activities as a priority to ensure that children who have had no access to vaccination in the last five years are adequately protected for VPDs as soon as possible.

Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.

Science.gov (United States)

Ogata, Shohei; Shimizu, Chisato; Franco, Alessandra; Touma, Ranim; Kanegaye, John T; Choudhury, Biswa P; Naidu, Natasha N; Kanda, Yutaka; Hoang, Long T; Hibberd, Martin L; Tremoulet, Adriana H; Varki, Ajit; Burns, Jane C

2013-01-01

Although intravenous immunoglobulin (IVIG) is highly effective in Kawasaki disease (KD), mechanisms are not understood and 10-20% of patients are treatment-resistant, manifesting a higher rate of coronary artery aneurysms. Murine models suggest that α2-6-linked sialic acid (α2-6Sia) content of IVIG is critical for suppressing inflammation. However, pro-inflammatory states also up-regulate endogenous levels of β-galactoside:α2-6 sialyltransferase-I (ST6Gal-I), the enzyme that catalyzes addition of α2-6Sias to N-glycans. We asked whether IVIG failures correlated with levels of α2-6Sia on infused IVIG or on the patient's own endogenous IgG. We quantified levels of α2-6Sia in infused IVIG and endogenous IgG from 10 IVIG-responsive and 10 resistant KD subjects using multiple approaches. Transcript levels of ST6GAL1, in patient whole blood and B cell lines were evaluated by RT-PCR. Plasma soluble (s)ST6Gal-I levels were measured by ELISA. There was no consistent difference in median sialylation levels of infused IVIG between groups. However, α2-6Sia levels in endogenous IgG, ST6GAL1 transcript levels, and ST6Gal-I protein in serum from IVIG-resistant KD subjects were lower than in responsive subjects at both pre-treatment and one-year time points (p treatment response in KD. Rather, lower sialylation of endogenous IgG and lower blood levels of ST6GALI mRNA and ST6Gal-I enzyme predict therapy resistance. These differences were stable over time, suggesting a genetic basis. Because IVIG-resistance increases risk of coronary artery aneurysms, our findings have important implications for the identification and treatment of such individuals.

Fertilizantes e espaçamento entre plantas na produtividade da couve-da-Malásia Fertilizers and spacing between plants in the yield of Malaysian cabbage

Directory of Open Access Journals (Sweden)

Wanessa Resende Ferreira

2002-12-01

Full Text Available As brássicas têm sido objeto constante de pesquisa devido à sua importância na alimentação humana, seja pela quantidade consumida, pelo alto valor nutricional ou por sua elevada produtividade. Brassica chinensis var. parachinensis foi introduzida no Brasil, Uberlândia, em 1992, destacando-se em relação a outras brássicas por seu alto teor de vitaminas A e C, cálcio e ferro, estando pronta para consumo em aproximadamente 30 dias. A produtividade biológica e agronômica dessa variedade foi analisada utilizando-se três tipos de fertilizantes e três espaçamentos entre plantas, visando subsidiar sua produção em escala comercial. A área foliar, massa da matéria seca e taxa de crescimento absoluto foram significativamente maiores com adubação mineral em relação à adubação orgânica. Os maiores valores referentes à taxa de crescimento relativo e taxa assimilatória líquida foram registrados em plantas mantidas nos maiores espaçamentos (30x20 e 30x30 cm. A maior produtividade agronômica foi alcançada no menor espaçamento (30x10 cm, com adubação mineral, sendo registrados 21,5 t ha-1, valor muito próximo ao registrado na Malásia e China onde essa hortaliça é cultivada em larga escala.Brassica crops have been widely studied due to their importance as food for human consumption, especially in relation to their nutritional value. Both yield and consumption are high. Brassica chinensis var. parachinensis was introduced in Brazil, in Uberlândia, in 1992, surpassing other Brassica due to its high content of vitamins A and C, calcium and iron, and being ready for consumption in about 30 days. The biological and agronomic yield of this variety was analyzed under three kinds of fertilizers and three spacings between plants with a view to its production on a commercial scale. The leaf area, dry matter mass, and absolute growth rate were higher with mineral than organic fertilizer. High values for relative growth rate and net

Polio eradication initiative in Afghanistan, 1997-2013.

Science.gov (United States)

Simpson, Diane M; Sadr-Azodi, Nahad; Mashal, Taufiq; Sabawoon, Wrishmeen; Pardis, Ajmal; Quddus, Arshad; Garrigos, Carmen; Guirguis, Sherine; Zahoor Zaidi, Syed Sohail; Shaukat, Shahzad; Sharif, Salmaan; Asghar, Humayan; Hadler, Stephen C

2014-11-01

This article reviews the epidemiology of polio, acute flaccid paralysis (AFP) surveillance, and the implementation of supplemental immunization activities (SIAs) in Afghanistan from 1997 thru 2013. Published reports and unpublished national data on polio cases, AFP surveillance, and SIAs were analyzed. Recommendations from independent advisory groups and Afghan government informed the conclusions. From 1997 thru 2013, the annual number of confirmed polio cases fluctuated from a low of 4 in 2004 to a high of 80 in 2011. Wild poliovirus types 2 and 3 were last reported in 1997 and 2010, respectively. Circulating vaccine-derived poliovirus type 2 emerged in 2009. AFP surveillance quality in children aged 8 per 100,000 population. Since 2001, at least 6 SIAs have been conducted annually. Afghanistan has made progress moving closer to eliminating polio. The program struggles to reach all children because of management and accountability problems in the field, inaccessible populations, and inadequate social mobilization. Consequently, too many children are missed during SIAs. Afghanistan adopted a national emergency action plan in 2012 to address these issues, but national elimination will require consistent and complete implementation of proven strategies. Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Addictive use of social networking sites can be explained by the interaction of Internet use expectancies, Internet literacy, and psychopathological symptoms.

Science.gov (United States)

Wegmann, Elisa; Stodt, Benjamin; Brand, Matthias

2015-09-01

Most people use the Internet in a functional way to achieve certain goals and needs. However, there is an increasing number of people who experience negative consequences like loss of control and distress based on an excessive use of the Internet and its specific online applications. Some approaches postulate similarities with behavioral addictions as well as substance dependencies. They differentiate between a generalized and a specific Internet addiction, such as the pathological use of social networking sites (SIA-SNS). Prior studies particularly identified the use of applications, personal characteristics, and psychopathological symptoms as significant predictors for the development and maintenance of this phenomenon. So far, it remains unclear how psychopathological symptoms like depression and social anxiety interact with individual expectancies of Internet use and capabilities of handling the Internet, summarized as Internet literacy. The current study (N = 334) investigated the interaction of these components in a structural equation model. The results indicate that the effects of depression and social anxiety on SIA-SNS were mediated by Internet use expectancies and self-regulation. Thus, Internet use expectancies seem to be crucial for SIA-SNS, which is in line with prior models. SNS use may be reinforced by experienced gratification and relief from negative feelings. Individual competences in handling the Internet may be preventive for the development of SIA-SNS.

Implementasi Sistem Informasi Akademik Menggunakan Aplikasi Jibas pada SMA Negeri 9 Padang

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Ricky Akbar

2015-10-01

Full Text Available SMA Negeri 9 Padang is one of the institutions engaged in the field of education, which requires the design of software to manage and run all school activities, one of which is the Academic Information System (SIA. SIA currently in SMA 9 Padang yet well integrated, so it still has many shortcomings in meeting the needs of the school or institution, in particular to deal with academic problems. Therefore, it needs to be implemented Academic Information System that can overcome the various shortcomings earlier. Implementation of this application starts with a preliminary study. Activities, the introduction of the school as a whole with interviews and observations, identify business processes academically at school is running and then make the proposed system as terkomputerisasinya, which is described by using the tools of Business Process Model Notation (BPMN, as well as the depiction of a working model of the system to be applied using use case diagram. The next stage is to study the literature of various books and journals to find the theoretical basis and related research. Then selecting software for SIA School, after the configuration and customization of the software modules, and the latter carry out the implementation and testing. These results indicate that the software SIA Schools that have been selected and applied that JIBAS applications, which can solve the problems on SMA Negeri 9 Padang

Digital archives, big data and image-based culturomics for social impact assessment: Opportunities and challenges

International Nuclear Information System (INIS)

Sherren, Kate; Parkins, John R.; Smit, Michael; Holmlund, Mona; Chen, Yan

2017-01-01

Social impact assessment (SIA) is well-established but uses conventional approaches that have become less effective in recent decades, particularly in relation to declining survey response rates and a lack of youth engagement. Images from digital archives and social media sources are poised to advance the research and practice of SIA by transcending text-based methods with insights into changing landscapes, and human engagement with them. This viewpoint describes progress, challenges and cautions toward the development of such tools (defined as culturomics), using hydroelectricity cases to illustrate potential approaches. These tools build on foundational work in a range of disciplines, including the humanities and computer science. We describe necessary advances in machine learning, image digitization, and data aggregation and visualization techniques, as well as ways to ensure that such tools are carefully tested, applied and interpreted. Challenges include the automation, acquisition and management of datasets, and using these tools appropriately and equitably. Critically, culturomics of any kind must not be used as a replacement for engagement with people, but as complementary to inclusive stakeholder engagement. - Highlights: •Image-based digital archives and social media present opportunities for new SIA tools. •Application-ready big data approaches are emerging across many fields. •SIA scholars, practitioners and stakeholders should engage with culturomics. •Challenges include automation, digitization, interpretation and justice. •Culturomics of any kind must not replace engagement with people.

Derivation of kinetic coefficients by atomistic methods for studying defect behavior in Mo

International Nuclear Information System (INIS)

Insepov, Z.; Rest, J.; Yacout, A.M.; Kuksin, A.Yu.; Norman, G.E.; Stegailov, V.V.; Starikov, S.V.; Yanilkin, A.V.

2012-01-01

Highlights: ► A multiscale concept couples molecular dynamics (MD) with ab initio and kinetic rate theory. ► Evolution of a system of self-interstitial atoms and vacancies in Mo is studied by MD. ► Formation of di-SIA clusters and SIA–vacancy recombination is analyzed. ► 1D diffusion of self-interstitials at various temperature and defect concentrations were studied. ► This paper provides a powerful predictive tool for simulating irradiation of nuclear materials. - Abstract: A multiscale concept for irradiated materials simulation is formulated based on coupling molecular dynamics simulations (MD) where the potential was obtained from ab initio data of energies of the basic defect structures, with kinetic mesoscale models. The evolution of a system containing self-interstitial atoms (SIAs) and vacancies in crystalline molybdenum is investigated by means of MD. The kinetics of formation of di-SIA clusters and SIA–vacancy recombination is analyzed via approaches used in the kinetic theory of radiation ageing. The effects of 1D diffusion of SIAs, temperature, and defect concentrations on the reaction rates are also studied. This approach can validate both the kinetic mechanisms and the appropriate kinetic coefficients, offering the potential to significantly reduce the uncertainty of the kinetic methodology and providing a powerful predictive tool for simulating irradiation behavior of nuclear materials.

UN’APPLICAZIONE ARCGIS PER LA SICUREZZA DEL COSTRUITO

Directory of Open Access Journals (Sweden)

Luigi Colombo

2013-08-01

Full Text Available La difesa delle città da eventi naturali, come i terremoti, richiede sia il miglioramento delle qualità costruttive degli edifici, sia la riduzione consistente della loro danneggiabilità. Questi requisiti sono conseguibili, per gli edifici di nuova costruzione, attraverso l’applicazione della normativa anti-simica, e, per quelli esistenti, utilizzando strumenti che si basano su un’attenta classificazione della predisposizione al danneggiamento (vulnerabilità, sia per l’aspetto costruttivo sia per quello strutturale, materico e geo-ambientale. The Italian land has a great amount of both ancient outstanding buildings and modern ones. Nowadays, risk evaluation and analysis are extremely useful to prevent the dangerous natural calamities, which have always been happening in Italy, involving both human lives and structures maintenance. This is a very complex problem which requires a wide knowledge concerning structural, material and territorial information: a GIS system could be the effective instrument able to automatize analysis processes, to provide thematic outputs and to help the users in operational choices and online analyses. The paper deals with a GIS application in the little town of Verdellino, close to Bergamo, which has been developed carrying out a detailed geo-database for seismic buildings classification. The experience has proved the meaningful role of informatics instruments in visualization, risk classification and in pre/ post events management for a more general safeguard.

UN’APPLICAZIONE ARCGIS PER LA SICUREZZA DEL COSTRUITO

Directory of Open Access Journals (Sweden)

Luigi Colombo

2013-08-01

Full Text Available La difesa delle città da eventi naturali, come i terremoti, richiede sia il miglioramento delle qualità costruttive degli edifici, sia la riduzione consistente della loro danneggiabilità. Questi requisiti sono conseguibili, per gli edifici di nuova costruzione, attraverso l’applicazione della normativa anti-simica, e, per quelli esistenti, utilizzando strumenti che si basano su un’attenta classificazione della predisposizione al danneggiamento (vulnerabilità, sia per l’aspetto costruttivo sia per quello strutturale, materico e geo-ambientale.The Italian land has a great amount of both ancient outstanding buildings and modern ones. Nowadays, risk evaluation and analysis are extremely useful to prevent the dangerous natural calamities, which have always been happening in Italy, involving both human lives and structures maintenance. This is a very complex problem which requires a wide knowledge concerning structural, material and territorial information: a GIS system could be the effective instrument able to automatize analysis processes, to provide thematic outputs and to help the users in operational choices and online analyses. The paper deals with a GIS application in the little town of Verdellino, close to Bergamo, which has been developed carrying out a detailed geo-database for seismic buildings classification. The experience has proved the meaningful role of informatics instruments in visualization, risk classification and in pre/ post events management for a more general safeguard.

Tallinna börsi uus lemmik / Armin Karu ; interv. Jaanika Merilo

Index Scriptorium Estoniae

Karu, Armin, 1965-

2006-01-01

Olympic Entertainment Group'i juht tutvustab ettevõtte börsile viimist, laienemisplaane Kesk- ja Ida-Euroopasse, olukorda kasiinoturul. Graafik: Olympic Entertainment Groupi aktsia kurss 23.-25. okt. 2006. Kommenteerivad Stefan Andersson, Kristjan Lepik, Kristjan Hänni, Tõnno Vähk, Peeter Koppel

Kes see möllab köögis? / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2009-01-01

Nora Ephroni filmist "Julie ja Julia" (USA 2009), mille stsenaariumi kirjutas ta kokku Julia Childi autobiograafia "My Life in France" ja Julie Powelli blogist raamatuks vormunud teose "Julie & Julia: 365 Days, 524 Recipes, 1 Tiny Apartment Kitchen" põhjal. Julia Childi rollis Meryl Streep. Lisaks Kairit Tsäro kommentaarid "Meryli maagia" ja "Süües saledaks"

BetOnMath azzardo e matematica a scuola

CERN Document Server

Andrà, Chiara; Verani, Marco

2016-01-01

Il libro ha origine dall'attività svolta durante il progetto "BetOnMath", un'esperienza di Matematica Civile finalizzata alla prevenzione dell'abuso di gioco d'azzardo tra gli studenti della scuola secondaria di secondo grado attraverso un insegnamento innovativo della matematica. In particolare, durante il progetto gli autori del libro hanno sviluppato un percorso didattico modulare sulla matematica del gioco d'azzardo che gli insegnanti di matematica delle scuole secondarie possono utilizzare sia per introdurre gli strumenti di base del calcolo delle probabilità sia per sensibilizzare sui rischi legati al gioco d'azzardo. Il libro descrive i pilastri metodologici e concettuali che hanno guidato la concezione e dato forma al percorso didattico, ovvero la centralità del ruolo dell'insegnante, l'uso dei simulatori di gioco, l'importanza delle attività di gruppo e il ruolo delle emozioni nell'affrontare e comprendere nuovi concetti matematici. Nel libro, ciascuno di questi pilastri è trattato sia mediante ...

Atomistic studies of nucleation of He clusters and bubbles in bcc iron

International Nuclear Information System (INIS)

Yang, L.; Deng, H.Q.; Gao, F.; Heinisch, H.L.; Kurtz, R.J.; Hu, S.Y.; Li, Y.L.; Zu, X.T.

2013-01-01

Atomistic simulations of the nucleation of He clusters and bubbles in bcc iron at 800 K have been carried out using the newly developed Fe–Fe interatomic potential, along with Ackland potential for the Fe–Fe interactions. Microstructure changes were analyzed in detail. We found that a He cluster with four He atoms is able to push out an iron interstitial from the cluster, creating a Frenkel pair. Small He clusters and self-interstitial atom (SIA) can migrate in the matrix, but He-vacancy (He-V) clusters are immobile. Most SIAs form clusters, and only the dislocation loops with a Burgers vector of b = 1/2 appear in the simulations. SIA clusters (or loops) are attached to He-V clusters for He implantation up to 1372 appm, while the He-V cluster–loop complexes with more than one He-V cluster are formed at the He concentration of 2057 appm and larger

Social impact assessment and public participation in China: A case study of land requisition in Guangzhou

International Nuclear Information System (INIS)

Tang Bosin; Wong Siuwai; Lau, Milton Chi-hong

2008-01-01

This study examines the current prospects for and obstacles facing the implementation of social impact assessment (SIA) and participatory planning in the People's Republic of China. During the past two decades, rapid urbanisation and the conversion of rural land for urban development have led to numerous social conflicts and tensions between the Chinese government and its people. SIA and public participation in development decisions have received increasing attention from the Chinese authorities as possible ways to tackle the problem. Based on a Guangzhou case study, this paper argues that the assessment and mitigation of adverse impacts on the community from urban development have been carried out with different objectives, core values and principles when compared with those in Western societies. It concludes that the poor prospects of SIA and collaborative planning in China lie not only in the weak framework for environmental legislation, but also in all institutions concerning state-society relations, the socialist governing ideology and traditional Chinese culture

Short forms of the Social Interaction Anxiety Scale and the Social Phobia Scale.

Science.gov (United States)

Fergus, Thomas A; Valentiner, David P; McGrath, Patrick B; Gier-Lonsway, Stephanie L; Kim, Hyun-Soo

2012-01-01

Mattick and Clarke's (1998) Social Interaction Anxiety Scale (SIAS) and Social Phobia Scale (SPS) are commonly used self-report measures that assess 2 dimensions of social anxiety. Given the need for short, readable measures, this research proposes short forms of both scales. Item-level analyses of readability characteristics of the SIAS and SPS items led to the selection of 6 items from each scale for use in the short forms. The SIAS and SPS short forms had reading levels at approximately the 6th and 5th grade level, respectively. Results using nonclinical (Study 1: N = 469) and clinical (Study 2: N = 145) samples identified these short forms as being factorially sound, possessing adequate internal consistency, and having strong convergence with their full-length counterparts. Moreover, these short forms showed convergence with other measures of social anxiety, showed divergence from measures assessing related constructs, and predicted concurrent interpersonal functioning. Recommendations for the use of these short forms are discussed.

Dimensional structure of the Social Interaction Anxiety Scale according to the analysis of data obtained with a German version.

Science.gov (United States)

Eidecker, Judith; Glöckner-Rist, Angelika; Gerlach, Alexander L

2010-08-01

The Social Interaction and Anxiety Scale (SIAS) is widely used to assess social interaction anxiety. Yet its dimensional structure is still not well-defined. Especially, the conceptual pertinence of three negatively keyed items has been challenged. In this study, dimensionality of the answers of a student sample to a German SIAS version was first analyzed exploratorily. Subsequently, we tested confirmatorily several measurement models specifying different SIAS dimensions, and investigated how these relate to extraversion. The most reasonable model was cross-validated relying on data from healthy controls and social phobia sufferers. All analyses involved methods suited for an adequate handling of ordinal data. The findings confirm that three negatively keyed items are dubious indicators of social interaction anxiety. Thus, only the remaining 17 items should be used for this purpose in future studies. Analyses of their psychometric properties show, in addition, that they apparently tap three different facets of social interaction anxiety. (c) 2010 Elsevier Ltd. All rights reserved.

Excellence in clinical laboratories: the standard ISO 15189:2007

Directory of Open Access Journals (Sweden)

Antonio Scipioni

2010-06-01

Full Text Available I laboratori clinici operano in stretto contatto con i pazienti e collaborano direttamente alla loro cura, in modo corresponsabile con i medici e i reparti ospedalieri. L’importanza della loro attività per la salute pubblica rende obbligatoria l’esplicitazione di alcuni punti finora spesso considerati ovvii. Ai pazienti dev’essere infatti garantito che: - i metodi di analisi utilizzati siano stati preliminarmente valutati, per confermare la loro rispondenza agli obiettivi dell’analisi stessa, verificati, per controllarne l’effettiva efficacia e, se necessario, validati per garantire che siano appropriati allo scopo; - il personale che esegue le analisi sia stato adeguatamente formato e quindi tecnicamente competente; - il laboratorio assicuri un’adeguata consulenza allo staff clinico che richiede le analisi, allo scopo di ottenere una sinergia tra il laboratorio e il clinico che ha in cura il paziente, sia nella fase di prelievo di materiale biologico, sia nella fase di interpretazione dei risultati. Tutto ciò è necessario per dimostrare ai pazienti

Microfinanza: analisi d’impatto di un programma in India

Directory of Open Access Journals (Sweden)

Tommaso Rondinella

2005-03-01

Full Text Available L’analisi d’impatto dei programmi di microfinanza è uno strumento utile sia per migliorare i servizi offerti sia per garantire ai donatori che il denaro concesso sia utilizzato per programmi efficaci nell’alleviare la povertà. Il presente lavoro è costituito da due parti: la prima è dedicata all’analisi d’impatto, la seconda all’analisi empirica sul campo. L’indagine è stata condotta attraverso l’utilizzo di uno strumento in grado di dare una indicazione chiara dei cambiamenti avvenuti nelle condizioni di vita dei beneficiari e con il pregio di essere applicabile a costi molto ridotti. I risultati ottenuti mostrano in che misura l’accesso al credito cambi le condizioni di vita dei più poveri inducendo consistenti aumenti del reddito familiare, dei risparmi, della diversificazione delle attività produttive e del consumo di cibo. Inoltre si osserva, all’interno dei nuclei familiari, un miglioramento della condizione femminile chiaramente dipendente dalla partecipazione al programma di microcredito

Lot quality assurance sampling to monitor supplemental immunization activity quality: an essential tool for improving performance in polio endemic countries.

Science.gov (United States)

Brown, Alexandra E; Okayasu, Hiromasa; Nzioki, Michael M; Wadood, Mufti Z; Chabot-Couture, Guillaume; Quddus, Arshad; Walker, George; Sutter, Roland W

2014-11-01

Monitoring the quality of supplementary immunization activities (SIAs) is a key tool for polio eradication. Regular monitoring data, however, are often unreliable, showing high coverage levels in virtually all areas, including those with ongoing virus circulation. To address this challenge, lot quality assurance sampling (LQAS) was introduced in 2009 as an additional tool to monitor SIA quality. Now used in 8 countries, LQAS provides a number of programmatic benefits: identifying areas of weak coverage quality with statistical reliability, differentiating areas of varying coverage with greater precision, and allowing for trend analysis of campaign quality. LQAS also accommodates changes to survey format, interpretation thresholds, evaluations of sample size, and data collection through mobile phones to improve timeliness of reporting and allow for visualization of campaign quality. LQAS becomes increasingly important to address remaining gaps in SIA quality and help focus resources on high-risk areas to prevent the continued transmission of wild poliovirus. © Crown copyright 2014.

Oportunidades de colaboración de los Servicios de Emergencias 112 en la vigilancia de la salud pública Opportunities for the 112 Emergency Service to collaborate in public health surveillance

Directory of Open Access Journals (Sweden)

Josefa María Aldana-Espinal

2005-04-01

Full Text Available La Consejería de Salud de Andalucía está implantando un Sistema Integrado de Alertas (SIA para mejorar la protección de la salud de la población mediante la respuesta adecuada a las alertas sanitarias. Emergencias 112 Andalucía es un servicio dirigido tanto a situaciones de carácter catastrófico como a otras que precisen intervención y coordinación multisectorial. Estas funciones hacen posible su colaboración con el SIA proporcionando información sobre una serie de incidencias medioambientales. Realizamos un estudio para caracterizar la información recibida y valorar su inclusión sistemática en el SIA, que incluyó alertas de enero a agosto de 2003. El número de incidencias comunicado al 112 fue de 656, intervalo entre meses de 45 a 117. Destaca la frecuencia de las referidas a riesgos naturales (50,15% y contaminación ambiental (26,07%. El 67,55% de las incidencias ocurrieron entre las 15.00 y las 8.00 horas del día siguiente. Por provincias, Sevilla registró el 24,5% y la mayor tasa correspondió a Huelva, con 4,74 incidencias/100.000 habitantes. Tanto las incidencias relacionadas con la atención sanitaria como los problemas medioambientales, los riesgos para la salud alimentaria y ocupacional y las alertas epidemiológicas son de elevado interés para el SIA, por lo que es necesario considerar la integración de los sistemas de información de los centros de emergencias en la vigilancia de la salud pública.The Andalusian Regional Ministry of Health is implementing an Alert Integrated System (SIA in order to improve the health protection of the population by means of the appropriate response to the sanitary alerts. «Emergencias 112 Andalucía» is a service aimed both to catastrophic situations and to the other ones needing intervention and multisectorial coordination. Theses functions make possible their collaboration with the SIA, furnishing it with information about a series of environmental incidents. A study has been

Validación de la escala de ansiedad en la interacción social en estudiantes universitarios mexicanos

OpenAIRE

Moral de la Rubia, José; Facultad de Psicología, Universidad Autónoma de Nuevo León. Monterrey, NL, Méico.; García Cadena, Cirilo Humberto; Facultad de Psicología. Universidad Autónoma de Nuevo León Monterrey, NL, México.; Antona Casas, César Jesús; Facultad de Psicología, Universidad Pontificia de Salamanca. C/ Compañía, 5. C.P. 37002 Salamanca, España

2013-01-01

Objetivo. El propósito de esta investigación fue validar la escala de ansiedad en la interacción social (Social Interaction Anxiety Scale [SIAS-20] de Mattick y Clarke, 1998) en una población de estudiantes universitarios mexicanos. Concretamente, se buscó validar la estructura unidimensional del SIAS-20, calcular su consistencia interna, describir su distribución, comparar diferencias de medias entre géneros, comprobar su validez criterial con el factor de fobia social del inventario de ansi...

Spatial interactions database development for effective probabilistic risk assessment

International Nuclear Information System (INIS)

Liming, J. K.; Dunn, R. F.

2008-01-01

In preparation for a subsequent probabilistic risk assessment (PRA) fire risk analysis update, the STP Nuclear Operating Company (STPNOC) is updating its spatial interactions database (SID). This work is being performed to support updating the spatial interactions analysis (SIA) initially performed for the original South Texas Project Electric Generating Station (STPEGS) probabilistic safely assessment (PSA) and updated in the STPEGS Level 2 PSA and IPE Report. S/A is a large-scope screening analysis performed for nuclear power plant PRA that serves as a prerequisite basis for more detailed location-dependent, hazard-spec analyses in the PRA, such as fire risk analysis, flooding risk analysis, etc. SIA is required to support the 'completeness' argument for the PRA scope. The objectives of the current SID development effort are to update the spatial interactions analysis data, to the greatest degree practical, to be consistent with the following: the as-built plant as of December 31, 2007 the in-effect STPNOC STPEGS Units 1 and 2 PRA the current technology and intent of NUREG/CR-6850 guidance for lire risk analysis database support the requirements for PRA SIA, including fire and flooding risk analysis, established by NRC Regulatory Guide 1.200 and the ASME PRA Standard (ASME RA-S-2002 updated through ASME RA-Sc-2007,) This paper presents the approach and methodology for state-of-the-art SID development and applications, including an overview of the SIA process for nuclear power plant PRA. The paper shows how current relational database technology and existing, conventional station information sources can be employed to collect, process, and analyze spatial interactions data for the plant in an effective and efficient manner to meet the often challenging requirements of industry guidelines and standards such as NUREG/CR-6850, NRC Regulatory Guide 1.200, and ASME RA-S-2002 (updated through ASME RA-Sc 2007). This paper includes tables and figures illustrating how SIA

The Journalists Initiatives on Immunisation Against Polio and Improved Acceptance of the Polio Vaccine in Northern Nigeria 2007-2015.

Science.gov (United States)

Warigon, Charity; Mkanda, Pascal; Banda, Richard; Zakari, Furera; Damisa, Eunice; Idowu, Audu; Bawa, Samuel; Gali, Emmanuel; Tegegne, Sisay G; Hammanyero, Kulchumi; Nsubuga, Peter; Korir, Charles; Vaz, Rui G

2016-05-01

The polio eradication initiative had major setbacks in 2003 and 2007 due to media campaigns in which renowned scholars and Islamic clerics criticized polio vaccines. The World Health Organization (WHO) partnered with journalists in 2007 to form the Journalists Initiatives on Immunisation Against Polio (JAP), to develop communication initiatives aimed at highlighting polio eradication activities and the importance of immunization in northern Nigeria. We evaluated the impact of JAP activities in Kaduna State by determining the total number of media materials produced and the number of newspaper clips and bulletins published in support of polio eradication. We also determined the number of households in noncompliant communities that became compliant with vaccination during 2015 supplementary immunization activities (SIAs) after JAP interventions and compared caregivers' sources of information about SIAs in 2007 before and after the JAP was formed. Since creation of the JAP, >500 reports have been published and aired, with most portraying polio vaccine positively. During June 2015 SIAs in high-risk wards of Kaduna STATE, JAP interventions resulted in vaccination of 5122 of 5991 children (85.5%) from noncompliant households. During early 2007, the number of caregivers who had heard about SIA rounds from the media increased from 26% in January, before the JAP was formed, to 33% in March, after the initiation of JAP activities. The formation of the JAP resulted in measurable improvement in the acceptance of polio vaccine in northern Nigeria. © 2016 World Health Organization; licensee Oxford Journals.

Activation of human naïve Th cells increases surface expression of GD3 and induces neoexpression of GD2 that colocalize with TCR clusters.

Science.gov (United States)

Villanueva-Cabello, Tania M; Mollicone, Rosella; Cruz-Muñoz, Mario E; López-Guerrero, Delia V; Martínez-Duncker, Iván

2015-12-01

CD4+ T helper lymphocytes (Th) orchestrate the immune response after their activation by antigen-presenting cells. Activation of naïve Th cells is reported to generate the reduction in surface epitopes of sialic acid (Sia) in α2,3 and α2,6 linkages. In this work, we report that in spite of this glycophenotype, anti-CD3/anti-CD28-activated purified human naïve Th cells show a significant increase in surface Sia, as assessed by metabolic labeling, compared with resting naïve Th cells, suggesting an increased flux of Sia toward Siaα2,8 glycoconjugates. To understand this increase as a result of ganglioside up-regulation, we observed that very early after activation, human naïve Th cells show an increased expression in surface GD3 and neoexpression of surface GD2 gangliosides, the latter clustering with the T cell receptor (TCR). Also, we report that in contrast to GM2/GD2 synthase null mice, lentiviral vector-mediated silencing of the GM2/GD2 synthase in activated human naïve Th cells reduced efficient TCR clustering and downstream signaling, as assessed by proliferation assays and IL-2 and IL-2R expression, pointing to an important role of this enzyme in activation of human naive Th cells. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Deficiência e autodeterminação humana: compaixão e insensibilidade no caso Vincent Humbert Human handicap and self-determination: compassion and insensibility in the Vincent Humbert case

Directory of Open Access Journals (Sweden)

Ray Pereira

2007-03-01

Full Text Available Discute a questão da autodeterminação de pessoas com deficiência, sem comprometimento das funções cognitivas. Traz como pano de fundo a história de Vincent Humbert, francês de 22 anos que ficou tetraplégico, cego e mudo após um acidente automobilístico. O sofrimento intenso do rapaz durou vários meses, resultando em insistente pedido de eutanásia aos médicos e à sua mãe. A morte de Humbert, após uma tentativa frustrada de eutanásia praticada pela mãe, reabre a polêmica em torno da eutanásia e do suicídio assistido. Partindo desse contexto, apresenta aspectos históricos da deficiência e analisa criticamente a autonomia e a eutanásia de Humbert.This work has the objective of discussing human self-determination among handicapped people with unaffected cognitive functions. The background for the article is the history of 22 year-old Vincent Humbert, who became tetraplegic, blind and speech-impaired after a car accident. The young man intense suffering lasted for several months and resulted in an insistent request for euthanasia to his mother. Humbert's death, after his mother's unsuccessful effort to conduct the euthanasia, restates the polemics concerning euthanasia and assisted suicide. In this context, the article presents historical aspects of human handicap and critically analyzes Humbert's autonomy and euthanasia.

Il concetto di storia della lingua nell'opera grammaticale di Benedetto Buommattei

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Gunver Skytte

1991-12-01

Full Text Available Che la storia della lingua sia una disciplina linguistica di data recente, fondata nell'800, soprattutto grazie alle ricerche pionieristiche di insigni filologi tedeschi, è un'opinione comunemente accettata, ed essa è probabilmente anche giustificata attraverso la classificazione datane di disciplina. A questo dato di fatto si deve senz'altro l'opinione altrettanto estesa che prima dell'800 non esistesse il concetto di linguistica diacronica o cambiamento linguistico in senso scientifico, come pure quella non meno erronea che la linguistica, come scienza, sia stata fondata solo nell'800.

On-line monitoring of Glucose and penicillin by sequential injection analysis

DEFF Research Database (Denmark)

Min, R.W.; Nielsen, Jens Bredal; Villadsen, John

1996-01-01

and a detector. The glucose analyzer is based on an enzymatic reaction using glucose oxidase, which converts glucose to glucono-lactone with formation of hydrogen peroxide and subsequent detection of H2O2 by a chemiluminescence reaction involving luminol. The penicillin analysis is based on formation......A sequential injection analysis (SIA) system has been developed for on-line monitoring of glucose and penicillin during cultivations of the filamentous fungus Penicillium chrysogenum. The SIA system consists of a peristaltic pump, an injection valve, two piston pumps, two multi-position valves...

Sobre algunos factores prosódicos en pacientes con afasia de Wernicke

OpenAIRE

Cabedo Nebot, Adrián

2009-01-01

Aquest treball d’investigació pretén fer una comparativa de caràcter descriptiu entre la prosòdia de pacients amb afàsia de Wernicke i la d’altres parlants que no experimenten aquest trastorn del llenguatge. En general, s’intenta observar el comportament idiosincràtic de la parla afàsica davant la no afàsica, sempre tenint en compte que, habitualment, l’afàsia fluent o de Wernicke es considera funcional i comuna des d’un punt de vista de l’articulació fonètica.

Sobre algunos factores prosódicos en pacientes con afasia de Wernicke

OpenAIRE

Cabedo Nebot, Adrián

2013-01-01

Aquest treball d’investigació pretén fer una comparativa de caràcter descriptiu entre la prosòdia de pacients amb afàsia de Wernicke i la d’altres parlants que no experimenten aquest trastorn del llenguatge. En general, s’intenta observar el comportament idiosincràtic de la parla afàsica davant la no afàsica, sempre tenint en compte que, habitualment, l’afàsia fluent o de Wernicke es considera funcional i comuna des d’un punt de vista de l’articulació fonètica.

L’intersoggettività e la sfera “emozionale-affettiva”. Appunti per una rilettura dell’analisi costitutiva

Directory of Open Access Journals (Sweden)

Luigi Muzzetto

2012-03-01

Full Text Available Nella prima parte del saggio si mette in risalto sia l’assunzione, nella sociologia classica, di affettività e razionalità come elementi contrapposti, sia la presenza degli aspetti fondamentali del superamento di tale visione dicotomica. La seconda parte riprende il pensiero di A. Schutz sull’intersoggettività come categoria base del sociale. Sebbene l’autore si muove in un’ottica cognitiva, il saggio evidenzia elementi presenti nel pensiero dell’autore che consentono di proporre una nuova concettualizzazione nella quale la dimensione affettivo-emozionale è presente ‘sin dall’inizio’.

Grand Tour: immaginario, territorio e culture digitali

Directory of Open Access Journals (Sweden)

Emiliano Ilardi

2016-12-01

Full Text Available Il Grand Tour può essere recuperato come asset narrativo utile per un intervento strategico di re-branding del viaggio in Italia? Il contributo analizza il contesto e le condizioni per una progettazione di questo livello nell’ambiente culturale dell’epoca digitale. Considerando gli archetipi moderni della mediazione dei luoghi come una grande riserva di senso, da riattivare sia nelle pratiche basate sui format seriali e transmediali che valorizzano i territori nella produzione creativa, sia nella costruzione di infrastrutture digitali e  transluoghi per la valorizzazione degli attrattori culturali.

The differential impact of oral poliovirus vaccine formulation choices on serotype-specific population immunity to poliovirus transmission.

Science.gov (United States)

Thompson, Kimberly M; Duintjer Tebbens, Radboud J

2015-09-17

Prior analyses demonstrated the need for some countries and the Global Polio Eradication Initiative (GPEI) to conduct additional supplemental immunization activities (SIAs) with trivalent oral poliovirus vaccine (tOPV) prior to globally-coordinated cessation of all serotype 2-containing OPV (OPV2 cessation) to prevent the creation of serotype 2 circulating vaccine-derived poliovirus (cVDPV2) outbreaks after OPV2 cessation. The GPEI continues to focus on achieving and ensuring interruption of wild poliovirus serotype 1 (WPV1) and making vaccine choices that prioritize bivalent OPV (bOPV) for SIAs, nominally to increase population immunity to serotype 1, despite an aggressive timeline for OPV2 cessation. We use an existing dynamic poliovirus transmission model of northwest Nigeria and an integrated global model for long-term poliovirus risk management to explore the impact of tOPV vs. bOPV vaccine choices on population immunity and cVDPV2 risks. Using tOPV instead of bOPV for SIAs leads to a minimal decrease in population immunity to transmission of serotypes 1 and 3 polioviruses, but a significantly higher population immunity to transmission of serotype 2 polioviruses. Failure to use tOPV in enough SIAs results in cVDPV2 emergence after OPV2 cessation in both the northwest Nigeria model and the global model. Despite perceptions to the contrary, prioritizing the use of bOPV over tOPV prior to OPV2 cessation does not significantly improve serotype 1 population immunity to transmission. Immunization leaders need to focus on all three poliovirus serotypes to appropriately manage the risks of OPV cessation in the polio endgame. Focusing on population immunity to transmission to interrupt WPV1 transmission and manage pre-OPV cessation risks of cVDPVs, all countries performing poliovirus SIAs should use tOPV up until the time of OPV2 cessation, after which time they should continue to use the OPV vaccine formulation with all remaining serotypes until coordinated global

Dependence of radiation damage accumulation in iron on underlying models of displacement cascades and subsequent defect migration

International Nuclear Information System (INIS)

Souidi, A.; Becquart, C.S.; Domain, C.; Terentyev, D.; Malerba, L.; Calder, A.F.; Bacon, D.J.; Stoller, R.E.; Osetsky, Yu. N.; Hou, M.

2006-01-01

Groups of displacement cascades calculated independently with different simulation models and computer codes are compared on a statistical basis. The parameters used for this comparison are the number of Frenkel pairs (FP) produced, the percentages of vacancies and self-interstitial atoms (SIAs) in clusters, the spatial extent and the aspect ratio of the vacancies and the SIAs formed in each cascade. One group of cascades was generated in the binary collision approximation (BCA) and all others by full molecular dynamics (MD). The MD results differ primarily due to the empirical interatomic potentials used and, to some extent, in code strategies. Cascades were generated in simulation boxes at different initial equilibrium temperatures. Only modest differences in the predicted numbers of FP are observed, but the other cascade parameters may differ by more than 100%. The consequences of these differences on long-term cluster growth in a radiation environment are examined by means of object kinetic Monte Carlo (OKMC) simulations. These were repeated with three different parameterizations of SIA and SIA cluster mobility. The differences encompassed low to high mobility, one- and three-dimensional migration of clusters, and complete immobility of large clusters. The OKMC evolution was followed until 0.1 dpa was reached. With the range of OKMC parameters used, cluster populations after 0.1 dpa differ by orders of magnitude. Using the groups of cascades from different sources induced no difference larger than a factor of 2 in the OKMC results. No correlation could be identified between the cascade parameters considered and the number densities of vacancies and SIAs predicted by OKMC to cluster in the long term. However, use of random point defect distributions instead of those obtained for displacement cascades as input for the OKMC modeling led to significantly different results. It is therefore suggested that although the displacement cascade characteristics considered

Infectious Disease Risk and Vaccination in Northern Syria after 5 Years of Civil War: The MSF Experience

Science.gov (United States)

de Lima Pereira, Alan; Southgate, Rosamund; Ahmed, Hikmet; O’Connor, Penelope; Cramond, Vanessa; Lenglet, Annick

2018-01-01

Introduction: In 2015, following an influx of population into Kobanê in northern Syria, Médecins Sans Frontières (MSF) in collaboration with the Kobanê Health Administration (KHA) initiated primary healthcare activities. A vaccination coverage survey and vaccine-preventable disease (VPD) risk analysis were undertaken to clarify the VPD risk and vaccination needs. This was followed by a measles Supplementary Immunization Activity (SIA). We describe the methods and results used for this prioritisation activity around vaccination in Kobanê in 2015. Methods: We implemented a pre-SIA survey in 135 randomly-selected households in Kobanê using a vaccination history questionnaire for all children Syria. The VPD Risk Analysis prioritised measles, Haemophilus Influenza type B (Hib) and Pneumococcus vaccinations. In the measles SIA, 3410 children aged 6-59 months were vaccinated. The use of multiple small vaccination sites to reduce risks associated with crowds in this active conflict setting was noted as a lesson learnt. The post-SIA survey estimated 82% (95%CI: 76.9-85.9%; n=229/280) measles vaccination coverage in children 6-59 months. Discussion: As a result of the conflict in Syria, the progressive collapse of the health care system in Kobanê has resulted in low vaccine coverage rates, particularly in younger age groups. The repeated displacements of the population, attacks on health institutions and exodus of healthcare workers, challenge the resumption of routine immunization in this conflict setting and limit the use of SIAs to ensure sustainable immunity to VPDs. We have shown that the risk for several VPDs in Kobanê remains high. Conclusion: We call on all health actors and the international community to work towards re-establishment of routine immunisation activities as a priority to ensure that children who have had no access to vaccination in the last five years are adequately protected for VPDs as soon as possible. PMID:29511602

Social Impact Management Plans: Innovation in corporate and public policy

Energy Technology Data Exchange (ETDEWEB)

Franks, Daniel M., E-mail: d.franks@uq.edu.au [Centre for Social Responsibility in Mining, The University of Queensland, Sustainable Minerals Institute, St Lucia, Brisbane, Queensland 4072 (Australia); Vanclay, Frank, E-mail: frank.vanclay@rug.nl [Department of Cultural Geography, Faculty of Spatial Sciences, The University of Groningen, P.O. Box 800, 9700 AV Groningen (Netherlands)

2013-11-15

Social Impact Assessment (SIA) has traditionally been practiced as a predictive study for the regulatory approval of major projects, however, in recent years the drivers and domain of focus for SIA have shifted. This paper details the emergence of Social Impact Management Plans (SIMPs) and undertakes an analysis of innovations in corporate and public policy that have put in place ongoing processes – assessment, management and monitoring – to better identify the nature and scope of the social impacts that might occur during implementation and to proactively respond to change across the lifecycle of developments. Four leading practice examples are analyzed. The International Finance Corporation (IFC) Performance Standards require the preparation of Environmental and Social Management Plans for all projects financed by the IFC identified as having significant environmental and social risks. Anglo American, a major resources company, has introduced a Socio-Economic Assessment Toolbox, which requires mine sites to undertake regular assessments and link these assessments with their internal management systems, monitoring activities and a Social Management Plan. In South Africa, Social and Labour Plans are submitted with an application for a mining or production right. In Queensland, Australia, Social Impact Management Plans were developed as part of an Environmental Impact Statement, which included assessment of social impacts. Collectively these initiatives, and others, are a practical realization of theoretical conceptions of SIA that include management and monitoring as core components of SIA. The paper concludes with an analysis of the implications for the practice of impact assessment including a summary of key criteria for the design and implementation of effective SIMPs. -- Highlights: • Social impact management plans are effective strategies to manage social issues. • They are developed in partnership with regulatory agencies, investors and community. �

Social Impact Management Plans: Innovation in corporate and public policy

International Nuclear Information System (INIS)

Franks, Daniel M.; Vanclay, Frank

2013-01-01

Social Impact Assessment (SIA) has traditionally been practiced as a predictive study for the regulatory approval of major projects, however, in recent years the drivers and domain of focus for SIA have shifted. This paper details the emergence of Social Impact Management Plans (SIMPs) and undertakes an analysis of innovations in corporate and public policy that have put in place ongoing processes – assessment, management and monitoring – to better identify the nature and scope of the social impacts that might occur during implementation and to proactively respond to change across the lifecycle of developments. Four leading practice examples are analyzed. The International Finance Corporation (IFC) Performance Standards require the preparation of Environmental and Social Management Plans for all projects financed by the IFC identified as having significant environmental and social risks. Anglo American, a major resources company, has introduced a Socio-Economic Assessment Toolbox, which requires mine sites to undertake regular assessments and link these assessments with their internal management systems, monitoring activities and a Social Management Plan. In South Africa, Social and Labour Plans are submitted with an application for a mining or production right. In Queensland, Australia, Social Impact Management Plans were developed as part of an Environmental Impact Statement, which included assessment of social impacts. Collectively these initiatives, and others, are a practical realization of theoretical conceptions of SIA that include management and monitoring as core components of SIA. The paper concludes with an analysis of the implications for the practice of impact assessment including a summary of key criteria for the design and implementation of effective SIMPs. -- Highlights: • Social impact management plans are effective strategies to manage social issues. • They are developed in partnership with regulatory agencies, investors and community. �

The New Evolution for SIA Rotorcraft UAV Project

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Juntong Qi

2010-01-01

Full Text Available This paper describes recent research on the design, implement, and testing of a new small-scaled rotorcraft Unmanned Aerial Vehicle (RUAV system—ServoHeli-40. A turbine-powered UAV weighted less than 15 kg was designed, and its major components were tested at the Shenyang Institute of Automation, Chinese Academy of Sciences in Shenyang, China. The aircraft was designed to reach a top speed of more than 20 mps, flying a distance of more than 10 kilometers, and it is going to be used as a test-bed for experimentally evaluating advanced control methodologies dedicated on improving the maneuverability, reliability, as well as autonomy of RUAV. Sensors and controller are all onboard. The full system has been tested successfully in the autonomous mode using the multichannel active modeling controller. The results show that in a real windy environment the rotorcraft UAV can follow the trajectory which was assigned by the ground control station exactly, and the new control method is obviously more effective than the one in the past year's research.

Dynamics of defect-loaded grain boundary under shear deformation in alpha iron

Science.gov (United States)

Yang, L.; Zhou, H. L.; Liu, H.; Gao, F.; Zu, X. T.; Peng, S. M.; Long, X. G.; Zhou, X. S.

2018-02-01

Two symmetric tilt grain boundaries (GBs) (Σ3〈110〉{112} and Σ11〈110〉{332}) in alpha iron were performed to investigate the dynamics of defect-loaded GBs under shear deformation. The results show that the loaded self-interstitial atoms (SIAs) reduce the critical stress of the coupled GB motion in the Σ3 GB, but increase the critical stress in the Σ11 GB. The loaded SIAs in the Σ3 GB easily form 〈111〉 clusters and remain in the bulk when the GB moves away. However, the SIAs move along with the Σ11 GB and combine with the vacancies in the bulk, leading to the defect self-healing. The helium (He) atoms loaded into the GBs significantly affect the coupled GB motion. Once He clusters emit interstitials, the Σ11 GB carries those interstitials away but the Σ3 does not. The loaded He atoms reduce the critical stress of the Σ3 GB, but increase the critical stress of the Σ11 GB.

Tuning of Rashba/Dresselhaus Spin Splittings by Inserting Ultra-Thin InAs Layers at Interfaces in Insulating GaAs/AlGaAs Quantum Wells.

Science.gov (United States)

Yu, Jinling; Zeng, Xiaolin; Cheng, Shuying; Chen, Yonghai; Liu, Yu; Lai, Yunfeng; Zheng, Qiao; Ren, Jun

2016-12-01

The ratio of Rashba and Dresselhaus spin splittings of the (001)-grown GaAs/AlGaAs quantum wells (QWs), investigated by the spin photocurrent spectra induced by circular photogalvanic effect (CPGE) at inter-band excitation, has been effectively tuned by changing the well width of QWs and by inserting a one-monolayer-thick InAs layer at interfaces of GaAs/AlGaAs QWs. Reflectance difference spectroscopy (RDS) is also employed to study the interface asymmetry of the QWs, whose results are in good agreement with that obtained by CPGE measurements. It is demonstrated that the inserted ultra-thin InAs layers will not only introduce structure inversion asymmetry (SIA), but also result in additional interface inversion asymmetry (IIA), whose effect is much stronger in QWs with smaller well width. It is also found that the inserted InAs layer brings in larger SIA than IIA. The origins of the additional SIA and IIA introduced by the inserted ultra-thin InAs layer have been discussed.

The factor structure of the Social Interaction Anxiety Scale and the Social Phobia Scale.

Science.gov (United States)

Heidenreich, Thomas; Schermelleh-Engel, Karin; Schramm, Elisabeth; Hofmann, Stefan G; Stangier, Ulrich

2011-05-01

The Social Interaction Anxiety Scale (SIAS) and the Social Phobia Scale (SPS) are two compendium measures that have become some of the most popular self-report scales of social anxiety. Despite their popularity, it remains unclear whether it is necessary to maintain two separate scales of social anxiety. The primary objective of the present study was to examine the factor analytic structure of both measures to determine the factorial validity of each scale. For this purpose, we administered both scales to 577 patients at the beginning of outpatient treatment. Analyzing both scales simultaneously, a CFA with two correlated factors showed a better fit to the data than a single factor model. An additional EFA with an oblique rotation on all 40 items using the WLSMV estimator further supported the two factor solution. These results suggest that the SIAS and SPS measure similar, but not identical facets of social anxiety. Thus, our findings provide support to retain the SIAS and SPS as two separate scales. Copyright © 2011 Elsevier Ltd. All rights reserved.

Smaller incision size leads to higher predictability in microcoaxial cataract surgery.

Science.gov (United States)

Klamann, Matthias K J; Gonnermann, Johannes; Maier, Anna-Karina B; Torun, Necip; Bertelmann, Eckart

2013-01-01

The aim of the study was to compare the clinical outcomes of a 1.8 mm, 2.2 mm, and 2.75 mm microcoaxial cataract surgery system. METHODS. In this retrospective study, 129 eyes of 129 patients were included. Patients underwent phacoemulsification using a Stellaris system or an Infiniti system. The incision size was 1.8 mm, 2.2 mm, or 2.75 mm, respectively. Subjects were examined before surgery and 4 weeks after. The surgically induced astigmatism (SIA) was examined. The SIA in the 1.8 mm group was statistically lower compared to the 2.2 mm group (p=0.046) and the 2.75 mm group (p=0.017). There was no significant difference between the 2.2 mm group and the 2.75 mm group. With the use of appropriate support systems, 1.8 mm incisions appear to result in less SIA than 2.2 mm and 2.75 mm incisions. Advantages may arise from this, especially in the implantation of aspheric, toric, or multifocal lenses.

Stakeholder Analysis as a Medium to Aid Change in Information System Reengineering Projects

Directory of Open Access Journals (Sweden)

Jean Davison

2004-04-01

Full Text Available The importance of involving stakeholders within a change process is well recognised, and successfully managed change is equally important. Information systems development and redesign is a form of change activity involving people and social issues and therefore resistance to change may occur. A stakeholder identification and analysis (SIA technique has been developed as an enhancement to PISO® (Process Improvement for Strategic Objectives, a method that engages the users of a system in the problem solving and reengineering of their own work-based problem areas. The SIA technique aids the identification and analysis of system stakeholders, and helps view the projected outcome of system changes and their effect on relevant stakeholders with attention being given to change resistance to ensure smooth negotiation and achieve consensus. A case study is presented here describing the successful implementation of a direct appointment booking system for patients within the National Health Service in the UK, utilising the SIA technique, which resulted in a feeling of empowerment and ownership of the change of those involved.

Characterization of a novel sialic acid transporter of the sodium solute symporter (SSS) family and in vivo comparison with known bacterial sialic acid transporters.

Science.gov (United States)

Severi, Emmanuele; Hosie, Arthur H F; Hawkhead, Judith A; Thomas, Gavin H

2010-03-01

The function of sialic acids in the biology of bacterial pathogens is reflected by the diverse range of solute transporters that can recognize these sugar acids. Here, we use an Escherichia coliDeltananT strain to characterize the function of known and proposed bacterial sialic acid transporters. We discover that the STM1128 gene from Salmonella enterica serovar Typhimurium, which encodes a member of the sodium solute symporter family, is able to restore growth on sialic acid to the DeltananT strain and is able to transport [(14)C]-sialic acid. Using the DeltananT genetic background, we performed a direct in vivo comparison of the transport properties of the STM1128 protein with those of sialic acid transporters of the major facilitator superfamily and tripartite ATP-independent periplasmic families, E. coli NanT and Haemophilus influenzae SiaPQM, respectively. This revealed that both STM1128 and SiaPQM are sodium-dependent and, unlike SiaPQM, both STM1128 and NanT are reversible secondary carriers, demonstrating qualitative functional differences in the properties of sialic acid transporters used by bacteria that colonize humans.

Integrating community perceptions and cultural diversity in social impact assessment in Nigeria

Energy Technology Data Exchange (ETDEWEB)

Nzeadibe, Thaddeus Chidi, E-mail: chidi.nzeadibe@unn.edu.ng [Department of Geography, University of Nigeria, 410001 Nsukka (Nigeria); Ajaero, Chukwuedozie Kelechukwu [Demography and Population Studies Programme, The University of Witwatersrand Johannesburg (South Africa); Okonkwo, Emeka Emmanuel; Okpoko, Patrick Uche [Department of Archaeology and Tourism, University of Nigeria, 410001 Nsukka (Nigeria); Akukwe, Thecla Iheoma [Department of Geography, University of Nigeria, 410001 Nsukka (Nigeria); Njoku-Tony, Roseline Feechi [Department of Environmental Technology, Federal University of Technology, Owerri (Nigeria)

2015-11-15

The Environmental Impact Assessment (EIA) Act of 1992 aimed to make the environment a central theme in development in Nigeria. Nevertheless, the extent of engagement with local cultures in the Nigerian EIA process is not statutorily guaranteed. While most EIAs in Nigeria have been for oil and gas projects in the Niger Delta, and have focused strongly on the biophysical environment, socio-economic and cultural aspects have remained marginal. The palpable neglect of community perceptions and cultural diversity in social impact assessment (SIA) in this region prone to conflict has tended to alienate the people in the decision-making process. Thus, despite claims to compliance with regulatory requirements for EIAs, and numerous purported sustainable development initiatives by international oil companies (IOCs), the region continues to face multiple sustainability challenges. This paper situates local perceptions and cultural diversity in participatory development and canvasses the integration of community perceptions and cultural diversity into SIA in the Niger Delta region. It is argued that doing this would be critical to ensuring acceptance and success of development actions within the context of local culture while also contributing to sustainable development policy in the region. - Highlights: • Nigeria EIA Act aimed to make the environment central to development in Nigeria. • Engagement with local communities in the process is not statutorily guaranteed. • SIAs in Nigeria neglect community perceptions and cultural diversity. • Article canvasses integrating community perceptions and cultural diversity in SIA. • Local acceptance in context of culture would yield sustainable development outcomes.

A human monoclonal antibody with neutralizing activity against highly divergent influenza subtypes.

Directory of Open Access Journals (Sweden)

Nicola Clementi

Full Text Available The interest in broad-range anti-influenza A monoclonal antibodies (mAbs has recently been strengthened by the identification of anti-hemagglutinin (HA mAbs endowed with heterosubtypic neutralizing activity to be used in the design of "universal" prophylactic or therapeutic tools. However, the majority of the single mAbs described to date do not bind and neutralize viral isolates belonging to highly divergent subtypes clustering into the two different HA-based influenza phylogenetic groups: the group 1 including, among others, subtypes H1, H2, H5 and H9 and the group 2 including, among others, H3 subtype. Here, we describe a human mAb, named PN-SIA28, capable of binding and neutralizing all tested isolates belonging to phylogenetic group 1, including H1N1, H2N2, H5N1 and H9N2 subtypes and several isolates belonging to group 2, including H3N2 isolates from the first period of the 1968 pandemic. Therefore, PN-SIA28 is capable of neutralizing isolates belonging to subtypes responsible of all the reported pandemics, as well as other subtypes with pandemic potential. The region recognized by PN-SIA28 has been identified on the stem region of HA and includes residues highly conserved among the different influenza subtypes. A deep characterization of PN-SIA28 features may represent a useful help in the improvement of available anti-influenza therapeutic strategies and can provide new tools for the development of universal vaccinal strategies.

A Chinese Herbal Medicine, Tokishakuyakusan, Reduces the Worsening of Impairments and Independence after Stroke: A 1-Year Randomized, Controlled Trial

Directory of Open Access Journals (Sweden)

Hirozo Goto

2011-01-01

Full Text Available In post-stroke patients, the recurrence of stroke and progression of impairments lead to a bedridden state and dementia. As for their treatments, only anti-hypertension and anti-coagulation therapies to prevent the recurrence of stroke are available. In Asia, post-stroke patients with impairments are often treated with herbal medicine. The present study evaluated the effectiveness of tokishakuyakusan (TS in improving the impairment and independence in post-stroke patients. Thirty-one post-stroke patients (mean age = 81.4 years were recruited and enrolled. Participants were randomly assigned to the TS group (n = 16 or non-treatment (control group (n = 15 and treated for 12 months. Impairments were assessed using the Stroke Impairment Assessment Set (SIAS. Independence was evaluated using the functional independence measure (FIM. For each outcome measure, mean change was calculated every 3 months. The results were that impairments according to SIAS did not significantly change in the TS group. In contrast, SIAS significantly worsened in the control group. There was a significant difference between the two groups. In each term of SIAS, affected lower extremity scores, abdominal muscle strength, function of visuospatial perception, and so forth. in the TS group were better than those in the control group. Independence according to FIM did not change significantly in the TS group. In contrast, FIM significantly worsened in the control group. There was also a significant difference between the two groups. In conclusion, TS was considered to suppress the impairments of lower limbs and to exert a favorable effect on cerebral function for post-stroke patients.

An Overview on Archival Inventories in the Web

Directory of Open Access Journals (Sweden)

Federico Valacchi

2011-05-01

Full Text Available In Italia il panorama degli strumenti di ricerca archivistica on-line è in continua espansione. Esso è caratterizzato da una accentuata multiformità redazionale e scientifica, segnato da articolate strategie di pubblicazione ed è costituito sia dall’insieme di dati pregressi confluiti nel web, sia da strumenti di più recente generazione. In mancanza del SAN (Sistema Archivistico Nazionale, non ancora ultimato, i punti di riferimento del sistema sono rappresentati dalla Guida Generale, dal  SIAS (Sistema Informativo degli Archivi di Stato e dal SIUSA (Sistema Informativo Unificato per le Soprintendenze Archivistiche. Inoltre, i singoli archivi di stato hanno progetti indipendenti di pubblicazione on-line dei propri strumenti, attraverso formati come il PDF, l'HTML o l'XML/EAD. In quest'ambito, va segnalata un'iniziativa dell’ICAR (Istituto Centrale per gli ARchivi, il quale ha pubblicato una ricognizione degli inventari realizzati da ogni Archivio e già disponibili online su SIAS e sui siti degli Istituti archivistici. Per quanto riguarda il SIUSA, esso offre, in collaborazione con progetti regionali, una vasta gamma di inventari, di cui due validi esempi sono costituiti dal progetto Rinasco in Lazio e dal .DOC in Umbria. Infine, vi sono i sistemi informativi tematici, come Archivi del Novecento, progetto volto a costituire una rete di archivi per la storia italiana. L'offerta è quindi molto vasta, ma al fine di un esaustivo controllo di una realtà così complessa, è necessaria la strutturazione di un sistema federato di risorse locali o tematiche interoperabili e compatibile con SIUSA e/o con il nascente SAN.

Integrating community perceptions and cultural diversity in social impact assessment in Nigeria

International Nuclear Information System (INIS)

Nzeadibe, Thaddeus Chidi; Ajaero, Chukwuedozie Kelechukwu; Okonkwo, Emeka Emmanuel; Okpoko, Patrick Uche; Akukwe, Thecla Iheoma; Njoku-Tony, Roseline Feechi

2015-01-01

The Environmental Impact Assessment (EIA) Act of 1992 aimed to make the environment a central theme in development in Nigeria. Nevertheless, the extent of engagement with local cultures in the Nigerian EIA process is not statutorily guaranteed. While most EIAs in Nigeria have been for oil and gas projects in the Niger Delta, and have focused strongly on the biophysical environment, socio-economic and cultural aspects have remained marginal. The palpable neglect of community perceptions and cultural diversity in social impact assessment (SIA) in this region prone to conflict has tended to alienate the people in the decision-making process. Thus, despite claims to compliance with regulatory requirements for EIAs, and numerous purported sustainable development initiatives by international oil companies (IOCs), the region continues to face multiple sustainability challenges. This paper situates local perceptions and cultural diversity in participatory development and canvasses the integration of community perceptions and cultural diversity into SIA in the Niger Delta region. It is argued that doing this would be critical to ensuring acceptance and success of development actions within the context of local culture while also contributing to sustainable development policy in the region. - Highlights: • Nigeria EIA Act aimed to make the environment central to development in Nigeria. • Engagement with local communities in the process is not statutorily guaranteed. • SIAs in Nigeria neglect community perceptions and cultural diversity. • Article canvasses integrating community perceptions and cultural diversity in SIA. • Local acceptance in context of culture would yield sustainable development outcomes

Il ruolo delle infrastrutture nella costruzione e nella percezione del territorio

Directory of Open Access Journals (Sweden)

Roberto Busi

2012-08-01

Full Text Available L’opera di pianificazione del paesaggio non può che passare attraverso la pianificazione delle componenti fisiche del territorio che, oltre agli indubitabili significati ed obiettivi funzionali, sono anche gli elementi costitutivi del paesaggio perché rappresentano le componenti percepibili del territorio medesimo; cosicché la pianificazione paesistica viene ad essere ad un tempo la diretta conseguenza e l’alta motivazione di quella urbanistico-territoriale conferendole motivi, fini e valori elevati.E le infrastrutture sono, come detto, le componenti fisiche primarie dell’antropizzazione del territorio sia in quanto tali, sia in quanto fattore per eccellenza di eventi generanti componenti fisiche.

Advice of the Italian CCTN on the toxicity of Cannabis sativa

Energy Technology Data Exchange (ETDEWEB)

Camoni, I [ed.; Istituto Superiore di Sanita` , Rome (Italy). Lab. di Tossicologia Applicata; Mucci, N [ed.; ISPESL, Monteporzio Catone, Roma (Italy). Dip. di Medicina del Lavoro; Paroli, E [ed.; Rome, Univ. ` La Sapienza` (Italy). Fac. di Medicina, Ist. di Farmacologia

1998-06-01

This recommendation of the Italian National Toxicological Committee (CCTN) regards the possible toxic effects of some products derived from Cannabis sativa, indica variety. The CCTN has especially evaluated genotoxic, immunological and toxic to reproduction effects of these substances, on the basis of the results from both experimental studies and observations on humans. [Italiano] Il documento contiene il parere della CCTN sui potenziali effetti tossici di alcuni derivati della Cannabis sativa, varieta` indica. Il parere e` stato elaborato sulla base dei risultati sia di studi sperimentali sia dei limitati studi sull`uomo, prendendo in particolare considerazione gli effetti genotossici, tossico-riproduttivi ed immunologici.

Sobre algunos factores prosódicos en pacientes con afasia de Wernicke

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Adrián Cabedo Nebot

2013-03-01

Full Text Available Aquest treball d’investigació pretén fer una comparativa de caràcter descriptiu entre la prosòdia de pacients amb afàsia de Wernicke i la d’altres parlants que no experimenten aquest trastorn del llenguatge. En general, s’intenta observar el comportament idiosincràtic de la parla afàsica davant la no afàsica, sempre tenint en compte que, habitualment, l’afàsia fluent o de Wernicke es considera funcional i comuna des d’un punt de vista de l’articulació fonètica.

Pacientes con fractura de cadera. Valoración de la cirugía precoz en estados de antiagregación plaquetaria

OpenAIRE

Mas i Atance, Jaume

2014-01-01

El tractament estàndard de la fractura de maluc és la cirurgia precoç sota anestèsia raquídia . S'ha descrit un augment de les complicacions quan el tractament es posposa més enllà de les 48 hores, sigui quin sigui el motiu de la demora . El maneig dels pacients amb fractura de maluc que a més es troben en tractament amb antiagregants plaquetaris ha generat controvèrsia, perquè en limitar la possibilitat d'una anestèsia regional, es tendeix a demorar la intervenció per evitar el risc d'una...

Variable impact of Malaysia's national language planning on non-Malay speakers in Sarawak Impacto variável do planejamento linguístico nacional da Malásia sobre não falantes do Malaio em Sarawak

Directory of Open Access Journals (Sweden)

Su-Hie Ting

2012-06-01

Full Text Available The study examined the impact of the national language policy on the language use of three main ethnic groups in the Malaysian state of Sarawak. The data analyzed was based on a sociolinguistic survey on language use in six domains that involved 937 Malay, Chinese and Iban adolescents from three major towns in Sarawak. The results showed that the use of Bahasa Malaysia exceeded English usage for all three ethnic groups, showing the success of compulsory education in the national language. However, the language planning has greater impact on the Iban than on the Chinese who are shifting away from the ethnic languages of the Chinese sub-groups to Mandarin Chinese. The availability of an alternative standard language with international standing which also functions as a symbol of cultural solidarity compromises the impact of the national language policy.Este estudo examinou o impacto da política de ensino da língua nacional de três principais grupos étnicos no estado malaio de Sarawak. Os dados analisados basearam-se em uma pesquisa sociolinguística sobre o uso da língua em seis domínios e envolveu 937 adolescentes malaios, chineses e Iban de três grandes cidades de Sarawak. Os resultados mostraram que o uso da língua Bahasa da Malásia superou o uso do inglês para todos os três grupos étnicos, comprovando o sucesso da escolaridade obrigatória em língua nacional. No entanto, o planejamento do estudo da língua tem maior impacto sobre o Iban do que sobre os chineses. Estes estão se afastando das línguas étnicas dos subgrupos chineses para o chinês Mandarim. A disponibilidade de uma língua alternativa padrão, com prestígio internacional, que também funciona como um símbolo de solidariedade cultural, compromete o impacto da política de ensino da língua nacional.

Optimisation of the enforcement of energy regulations and the use of SIA building standards; Optimierung Energievollzug und Anwendung der SIA-Normen Gebaeude

Energy Technology Data Exchange (ETDEWEB)

Dettli, R.; Baur, M.; Signer, B. [Econcept AG, Zuerich (Switzerland); Renaud, P.; Wermeille, Ch. [Planair, Bureau d' ingenieurs SIA, La Sagne (Switzerland)

2003-07-01

This report for the Swiss Federal Office of Energy (SFOE) presents the results of a study made on the effectiveness of the enforcement of energy legislation and the value of standards in planning and building activities. The reasons for deficiencies in the enforcement of regulations are examined and suggestions are made for improving the situation. Enforcement problems are discussed, including, for example, the partly insufficient capacities at the building authority level. Detailed measures are proposed at the federal and cantonal level and better training and know-how for building professionals is recommended. Those responsible for enforcement - usually the local authorities - are advised to improve the communication of their supervisory activities. Certain improvements to legislation are proposed and professional institutions are motivated to improve quality management and the know-how of their members. The report is completed with a comprehensive list of literature on the subject.

Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26.

Directory of Open Access Journals (Sweden)

Erica Z McAuley

Full Text Available We previously identified a significant bipolar spectrum disorder linkage peak on 15q25-26 using 35 extended families with a broad clinical phenotype, including bipolar disorder (types I and II, recurrent unipolar depression and schizoaffective disorder. However, the specific gene(s contributing to this signal had not been identified. By a fine mapping association study in an Australian case-control cohort (n = 385, we find that the sialyltransferase 8B (ST8SIA2 gene, coding for an enzyme that glycosylates proteins involved in neuronal plasticity which has previously shown association to both schizophrenia and autism, is associated with increased risk to bipolar spectrum disorder. Nominal single point association was observed with SNPs in ST8SIA2 (rs4586379, P = 0.0043; rs2168351, P = 0.0045, and a specific risk haplotype was identified (frequency: bipolar vs controls = 0.41 vs 0.31; χ(2 = 6.46, P = 0.011, OR = 1.47. Over-representation of the specific risk haplotype was also observed in an Australian schizophrenia case-control cohort (n = 256 (χ(2 = 8.41, P = 0.004, OR = 1.82. Using GWAS data from the NIMH bipolar disorder (n = 2055 and NIMH schizophrenia (n = 2550 cohorts, the equivalent haplotype was significantly over-represented in bipolar disorder (χ(2 = 5.91, P = 0.015, OR = 1.29, with the same direction of effect in schizophrenia, albeit non-significant (χ(2 = 2.3, P = 0.129, OR = 1.09. We demonstrate marked down-regulation of ST8SIA2 gene expression across human brain development and show a significant haplotype×diagnosis effect on ST8SIA2 mRNA levels in adult cortex (ANOVA: F(1,87 = 6.031, P = 0.016. These findings suggest that variation the ST8SIA2 gene is associated with increased risk to mental illness, acting to restrict neuronal plasticity and disrupt early neuronal network formation, rendering the developing and adult brain more vulnerable to

Carbon isotopes in otolith amino acids identify residency of juvenile snapper (Family: Lutjanidae) in coastal nurseries

KAUST Repository

McMahon, Kelton; Berumen, Michael L.; Mateo, Ivan; Elsdon, Travis S.; Thorrold, Simon R.

2011-01-01

This study explored the potential for otolith geochemistry in snapper (Family: Lutjanidae) to identify residency in juvenile nursery habitats with distinctive carbon isotope values. Conventional bulk otolith and muscle stable isotope analyses (SIA) and essential amino acid (AA) SIA were conducted on snapper collected from seagrass beds, mangroves, and coral reefs in the Red Sea, Caribbean Sea, and Pacific coast of Panama. While bulk stable isotope values in otoliths showed regional differences, they failed to distinguish nursery residence on local scales. Essential AA δ13C values in otoliths, on the other hand, varied as a function of habitat type and provided a better tracer of residence in different juvenile nursery habitats than conventional bulk otolith SIA alone. A strong linear relationship was found between paired otolith and muscle essential AA δ13C values regardless of species, geographic region, or habitat type, indicating that otolith AAs recorded the same dietary information as muscle AAs. Juvenile snapper in the Red Sea sheltered in mangroves but fed in seagrass beds, while snapper from the Caribbean Sea and Pacific coast of Panama showed greater reliance on mangrove-derived carbon. Furthermore, compound-specific SIA revealed that microbially recycled detrital carbon, not water-column-based new phytoplankton carbon, was the primary carbon source supporting snapper production on coastal reefs of the Red Sea. This study presented robust tracers of juvenile nursery residence that will be crucial for reconstructing ontogenetic migration patterns of fishes among coastal wetlands and coral reefs. This information is key to determining the importance of nursery habitats to coral reef fish populations and will provide valuable scientific support for the design of networked marine-protected areas. © 2011 Springer-Verlag.

Carbon isotopes in otolith amino acids identify residency of juvenile snapper (Family: Lutjanidae) in coastal nurseries

KAUST Repository

McMahon, Kelton

2011-08-26

This study explored the potential for otolith geochemistry in snapper (Family: Lutjanidae) to identify residency in juvenile nursery habitats with distinctive carbon isotope values. Conventional bulk otolith and muscle stable isotope analyses (SIA) and essential amino acid (AA) SIA were conducted on snapper collected from seagrass beds, mangroves, and coral reefs in the Red Sea, Caribbean Sea, and Pacific coast of Panama. While bulk stable isotope values in otoliths showed regional differences, they failed to distinguish nursery residence on local scales. Essential AA δ13C values in otoliths, on the other hand, varied as a function of habitat type and provided a better tracer of residence in different juvenile nursery habitats than conventional bulk otolith SIA alone. A strong linear relationship was found between paired otolith and muscle essential AA δ13C values regardless of species, geographic region, or habitat type, indicating that otolith AAs recorded the same dietary information as muscle AAs. Juvenile snapper in the Red Sea sheltered in mangroves but fed in seagrass beds, while snapper from the Caribbean Sea and Pacific coast of Panama showed greater reliance on mangrove-derived carbon. Furthermore, compound-specific SIA revealed that microbially recycled detrital carbon, not water-column-based new phytoplankton carbon, was the primary carbon source supporting snapper production on coastal reefs of the Red Sea. This study presented robust tracers of juvenile nursery residence that will be crucial for reconstructing ontogenetic migration patterns of fishes among coastal wetlands and coral reefs. This information is key to determining the importance of nursery habitats to coral reef fish populations and will provide valuable scientific support for the design of networked marine-protected areas. © 2011 Springer-Verlag.

Ab initio study of interstitial cluster interaction with Re, Os, and Ta in W

Energy Technology Data Exchange (ETDEWEB)

Setyawan, Wahyu, E-mail: wahyu.setyawan@pnnl.gov; Nandipati, Giridhar; Kurtz, Richard J.

2017-02-15

The stability of tungsten self-interstitial atom (SIA) clusters is studied using first-principles methods. Clusters from one to seven SIAs are systematically explored from 1264 unique configurations. Finite-size effect of the simulation cell is corrected based on the scaling of formation energy versus inverse volume cell. Furthermore, the accuracy of the calculations is improved by treating the 5p semicore states as valence states. Configurations of the three most stable clusters in each cluster size n are presented, which consist of parallel [111] dumbbells. The evolution of these clusters leading to small dislocation loops is discussed. The binding energy of size-n clusters is analyzed relative to an n → (n-1) + 1 dissociation and is shown to increase with size. Extrapolation for n > 7 is presented using a dislocation loop model. In addition, the interaction of these clusters with a substitutional Re, Os, or Ta solute is explored by replacing one of the dumbbells with the solute. Re and Os strongly attract these clusters, but Ta strongly repels. The strongest interaction is found when the solute is located on the periphery of the cluster rather than in the middle. The magnitude of this interaction decreases with cluster size. Empirical fits to describe the trend of the solute binding energy are presented. - Highlights: • Systematic DFT exploration of tungsten SIA clusters from 1264 configurations. • Detailed structures of several most stable clusters are presented. • Novel finding of the trend of solute binding of Re, Os, and Ta with SIA clusters. • Empirical models that describe the trends of the solute binding energies.

Members of a novel protein family containing microneme adhesive repeat domains act as sialic acid-binding lectins during host cell invasion by apicomplexan parasites.

Science.gov (United States)

Friedrich, Nikolas; Santos, Joana M; Liu, Yan; Palma, Angelina S; Leon, Ester; Saouros, Savvas; Kiso, Makoto; Blackman, Michael J; Matthews, Stephen; Feizi, Ten; Soldati-Favre, Dominique

2010-01-15

Numerous intracellular pathogens exploit cell surface glycoconjugates for host cell recognition and entry. Unlike bacteria and viruses, Toxoplasma gondii and other parasites of the phylum Apicomplexa actively invade host cells, and this process critically depends on adhesins (microneme proteins) released onto the parasite surface from intracellular organelles called micronemes (MIC). The microneme adhesive repeat (MAR) domain of T. gondii MIC1 (TgMIC1) recognizes sialic acid (Sia), a key determinant on the host cell surface for invasion by this pathogen. By complementation and invasion assays, we demonstrate that TgMIC1 is one important player in Sia-dependent invasion and that another novel Sia-binding lectin, designated TgMIC13, is also involved. Using BLAST searches, we identify a family of MAR-containing proteins in enteroparasitic coccidians, a subclass of apicomplexans, including T. gondii, suggesting that all these parasites exploit sialylated glycoconjugates on host cells as determinants for enteric invasion. Furthermore, this protein family might provide a basis for the broad host cell range observed for coccidians that form tissue cysts during chronic infection. Carbohydrate microarray analyses, corroborated by structural considerations, show that TgMIC13, TgMIC1, and its homologue Neospora caninum MIC1 (NcMIC1) share a preference for alpha2-3- over alpha2-6-linked sialyl-N-acetyllactosamine sequences. However, the three lectins also display differences in binding preferences. Intense binding of TgMIC13 to alpha2-9-linked disialyl sequence reported on embryonal cells and relatively strong binding to 4-O-acetylated-Sia found on gut epithelium and binding of NcMIC1 to 6'sulfo-sialyl Lewis(x) might have implications for tissue tropism.

Colloquium paper: uniquely human evolution of sialic acid genetics and biology.

Science.gov (United States)

Varki, Ajit

2010-05-11

Darwinian evolution of humans from our common ancestors with nonhuman primates involved many gene-environment interactions at the population level, and the resulting human-specific genetic changes must contribute to the "Human Condition." Recent data indicate that the biology of sialic acids (which directly involves less than 60 genes) shows more than 10 uniquely human genetic changes in comparison with our closest evolutionary relatives. Known outcomes are tissue-specific changes in abundant cell-surface glycans, changes in specificity and/or expression of multiple proteins that recognize these glycans, and novel pathogen regimes. Specific events include Alu-mediated inactivation of the CMAH gene, resulting in loss of synthesis of the Sia N-glycolylneuraminic acid (Neu5Gc) and increase in expression of the precursor N-acetylneuraminic acid (Neu5Ac); increased expression of alpha2-6-linked Sias (likely because of changed expression of ST6GALI); and multiple changes in SIGLEC genes encoding Sia-recognizing Ig-like lectins (Siglecs). The last includes binding specificity changes (in Siglecs -5, -7, -9, -11, and -12); expression pattern changes (in Siglecs -1, -5, -6, and -11); gene conversion (SIGLEC11); and deletion or pseudogenization (SIGLEC13, SIGLEC14, and SIGLEC16). A nongenetic outcome of the CMAH mutation is human metabolic incorporation of foreign dietary Neu5Gc, in the face of circulating anti-Neu5Gc antibodies, generating a novel "xeno-auto-antigen" situation. Taken together, these data suggest that both the genes associated with Sia biology and the related impacts of the environment comprise a relative "hot spot" of genetic and physiological changes in human evolution, with implications for uniquely human features both in health and disease.

An in-situ field ion microscope study of irradiated tungsten and tungsten alloys. II. The recovery behavior in Stages I and II: experimental results. Report No. 2347

International Nuclear Information System (INIS)

Wilson, K.L.; Seidman, D.N.

1974-12-01

The low temperature FIM isochronal annealing spectrum of four different purity levels of tungsten (resistivity ratios R of 5 . 10 4 , 1.5 . 10 4 , 50 and 15), irradiated in-situ with 30 keV W + ions to a dose of 5 . 10 12 ion cm -2 at 18 K, consisted of distinct recovery peaks at approximately 38, 50, 65 and 80 K with a small amount of recovery observed up to 120 K. The spectra were essentially identical between 18 and 120 K, but a fifth group of W specimens with approximately equal to 5 began to exhibit some deviations from the standard spectrum. This result indicates that the distribution of self-interstitial atoms (SIAs) produced by the ion irradiations in the W FIM tips was such that the SIA-SIA reaction dominated the recovery behavior. The isochronal peak width at half-maximum for the 38 K long-range SIA migration peak and the Stage II peaks in pure W were shown to be approximately equal to the value predicted by a diffusion model. The isochronal recovery spectra for W--0.5 at. per cent and 3 at. per cent Re alloys were radically different from the isochronal recovery spectra of pure W. For both W--Re alloys, the amount of recovery for the long-range migration peak was suppressed, and, for the 3 at. per cent Re alloy, it was almost eliminated. High-purity W (R = 5 . 10 4 ), doped with 50-100 appm carbon, showed a 20 per cent reduction in the amount of recovery observed for the long-range migration peak at 38 K. (U.S.)

Ab initio study of interstitial cluster interaction with Re, Os, and Ta in W

International Nuclear Information System (INIS)

Setyawan, Wahyu; Nandipati, Giridhar; Kurtz, Richard J.

2017-01-01

The stability of tungsten self-interstitial atom (SIA) clusters is studied using first-principles methods. Clusters from one to seven SIAs are systematically explored from 1264 unique configurations. Finite-size effect of the simulation cell is corrected based on the scaling of formation energy versus inverse volume cell. Furthermore, the accuracy of the calculations is improved by treating the 5p semicore states as valence states. Configurations of the three most stable clusters in each cluster size n are presented, which consist of parallel [111] dumbbells. The evolution of these clusters leading to small dislocation loops is discussed. The binding energy of size-n clusters is analyzed relative to an n → (n-1) + 1 dissociation and is shown to increase with size. Extrapolation for n > 7 is presented using a dislocation loop model. In addition, the interaction of these clusters with a substitutional Re, Os, or Ta solute is explored by replacing one of the dumbbells with the solute. Re and Os strongly attract these clusters, but Ta strongly repels. The strongest interaction is found when the solute is located on the periphery of the cluster rather than in the middle. The magnitude of this interaction decreases with cluster size. Empirical fits to describe the trend of the solute binding energy are presented. - Highlights: • Systematic DFT exploration of tungsten SIA clusters from 1264 configurations. • Detailed structures of several most stable clusters are presented. • Novel finding of the trend of solute binding of Re, Os, and Ta with SIA clusters. • Empirical models that describe the trends of the solute binding energies.

Trophic interactions between native and introduced fish species in a littoral fish community.

Science.gov (United States)

Monroy, M; Maceda-Veiga, A; Caiola, N; De Sostoa, A

2014-11-01

The trophic interactions between 15 native and two introduced fish species, silverside Odontesthes bonariensis and rainbow trout Oncorhynchus mykiss, collected in a major fishery area at Lake Titicaca were explored by integrating traditional ecological knowledge and stable-isotope analyses (SIA). SIA suggested the existence of six trophic groups in this fish community based on δ(13)C and δ(15)N signatures. This was supported by ecological evidence illustrating marked spatial segregation between groups, but a similar trophic level for most of the native groups. Based on Bayesian ellipse analyses, niche overlap appeared to occur between small O. bonariensis (<90 mm) and benthopelagic native species (31.6%), and between the native pelagic killifish Orestias ispi and large O. bonariensis (39%) or O. mykiss (19.7%). In addition, Bayesian mixing models suggested that O. ispi and epipelagic species are likely to be the main prey items for the two introduced fish species. This study reveals a trophic link between native and introduced fish species, and demonstrates the utility of combining both SIA and traditional ecological knowledge to understand trophic relationships between fish species with similar feeding habits. © 2014 The Fisheries Society of the British Isles.

Relaxation volumes of self-interstitial-atoms and vacancies in metals

International Nuclear Information System (INIS)

Ehrhart, P.

1983-01-01

Experimental results for the relaxation volumes of self-interstitial-atoms and vacancies as obtained after low temperature irradiation of different metals are reviewed. For fcc metals the relaxation volumes of the SIA's are very similar: ΔVsup(rel) = 1.6 +- 0.3 atomic volumes. This value is valid as well for the pure fcc metals (Al, Cu, Ni) as for different alloys. Vacancy relaxation volumes are small and vary between: ΔVsup(rel) = -0.05 and -0.25 atomic volumes. For bcc metals (Fe, Mo) the relaxation volume of the SIA is significantly smaller: ΔVsup(rel) = 1.1 +- 0.2 atomic volumes. In spite of the obvious similarity of the close-packed fcc and hcp structures, the SIA parameters for hcp metals are much different: ΔVsup(rel) = 3.5 for Zn, ΔVsup(rel) = 1.5 for Co and ΔVsup(rel) = 0.6 at. vol. for Zr. Vacancy relaxation volumes seem to be small as in cubic metals. The influence of lattice nonharmonicity on the validity of an extrapolation of the values determined at 6 K to higher temperatures is discussed. (author)

Principles for social impact assessment: A critical comparison between the international and US documents

International Nuclear Information System (INIS)

Vanclay, Frank

2006-01-01

The 'International Principles for Social Impact Assessment' and the 'Principles and Guidelines for Social Impact Assessment in the USA', both developed under the auspices of the International Association for Impact Assessment and published in 2003, are compared. Major differences in the definition and approach to social impact assessment (SIA) are identified. The US Principles and Guidelines is shown to be positivist/technocratic while the International Principles is identified as being democratic, participatory and constructivist. Deficiencies in both documents are identified. The field of SIA is changing to go beyond the prevention of negative impacts, to include issues of building social capital, capacity building, good governance, community engagement and social inclusion

An atlas of classification. Signage between open shelves, the Web and the catalogue

Directory of Open Access Journals (Sweden)

Andrea Fabbrizzi

2014-05-01

Questa segnaletica è fondata sulla comunicazione cross-mediale, e integra le modalità comunicative della biblioteca a vari livelli, sia nel contesto dello stesso medium, sia tra media diversi: tra i cartelli sulle testate degli scaffali, tra questi cartelli e il sito web della biblioteca, tra il sito web e il catalogo. Per questo sistema integrato sono particolarmente adatti i dispositivi mobili come i tablet e gli smartphone, perché danno la possibilità di accedere al Web mentre ci si muove tra gli scaffali. Il collegamento diretto tra gli scaffali aperti classificati e il catalogo è reso possibile dai codici QR stampati sui cartelli.

Age of Onset in Schizophrenia Spectrum Disorders: Complex Interactions between Genetic and Environmental Factors.

Science.gov (United States)

Mandelli, Laura; Toscano, Elena; Porcelli, Stefano; Fabbri, Chiara; Serretti, Alessandro

2016-03-01

In this study we evaluated the role of a candidate gene for major psychosis, Sialyltransferase (ST8SIA2), in the risk to develop a schizophrenia spectrum disorders, taking into account exposure to stressful life events (SLEs). Eight polymorphisms (SNPs) were tested in 94 Schizophreniainpatients and 176 healthy controls. Schizophrenia patients were also evaluated for SLEs in different life periods. None of the SNPs showed association with schizophrenia. Nevertheless, when crossing genetic variants with childhood SLEs, we could observe trends of interaction with age of onset. Though several limitations, our results support a protective role of ST8SIA2 in individuals exposed to moderate childhood stress.

Evoluzioni psicoanalitiche e cambiamento in psicoterapia psicoanalitica

Directory of Open Access Journals (Sweden)

Rosario Di Sauro

2009-06-01

Full Text Available In questo articolo si prende in considerazione l’evoluzione teoretica della psicoanalisi, passando dal modello freudiano monadico ad un approccio di matrice relazionale.  Altresì  viene evidenziato il contributo della psicologia clinica come elemento costitutivo della psicoterapia psicoanalitica, come espressività del continuum psicologia clinica-psicoterapia. Tutto ciò rappresenta, inoltre, la conditio sine qua non per il cambiamento terapeutico. Se ne evidenziano, infatti gli elementi caratteristici per una buona riuscita del processo terapeutico. L’Autore inoltre, mette in rilievo il ruolo della psicocorporeità nel trattamento psicoanalitico, sia come comunicazione del ‘non verbale’ sia come costrutto epistemologico di un nuovo apporto alla scienza psicoanalitica.

Sia la luce origini e destino del nostro universo

CERN Document Server

Longair, Malcolm S

1998-01-01

Una nuova visione dell'universo ; nascita ed evoluzione delle stelle ; quando muore una stella ; la "quasar connection" ; pulsar & co. ; gli inquietanti buchi neri ; le galassie e la nascita dell'universo.

Coastal dynamics physical and mathematical modelling, territorial analysis, G.I.S. instrumentation. The state of the arts; La dinamica costiera modellistica fisico-matematica, analisi del territorio, il supporto G.I.S. e la strumentazione in uso

Energy Technology Data Exchange (ETDEWEB)

De Bonis, P; Fattorusso, G; Onori, F; Pagano, A; Pasanisi, F; Peloso, A; Regina, P; Tebano, C; Zarlenga, F [ENEA, Div. Caratterizzazione dell' Ambiente, Centro Ricerche Casaccia, S. Maria di Galeria, Rome (Italy)

2001-07-01

The aim of the present work is to offer, in a single volume, the basic notions relative to different aspects, both theoretical and practical, of the study of coastal dynamical processes. It has been dealt with geological issues, physical and mathematical modelling, effects related to human activities, Geographical Information Systems as well as both laboratory and fields instrumentations. Reading this technical paper it has to keep in mind two aspects which have been authors guidelines. First of all, the research theme's have been studied on their theoretical aspects, focusing on the most recent developments. Then have been selected some up to date experiences and discuss their application. The general framework of this publication, which necessarily leave out some particular issues, for which the readers are to be referred to the references, gives a synthetic and homogenous picture of the state of the arts in coastal modelling. [Italian] Lo scopo della presente pubblicazione e' quello di offrire, in un unico volume, le nozioni di base riguardo ai diversi argomenti sia teorici sia pratici relativi all'analisi delle dinamiche costiere. Sono stati affrontati i temi relativi alla geologia, alla modellistica fisica e matematica, ai fattori di pressione antropica, all'utilizzo di Sistemi Informativi Geografici e alla strumentazione sia di campo sia di laboratorio. Nello sviluppo del presente Rapporto Tecnico si possono individuare per ciascuna delle aree di interesse due aspetti fondamentali. Dapprima i temi di ricerca sono stati studiati da un punto di vista teorico generale, con attenzione agli sviluppi piu' attuali e successivamente sono state presentate alcune recenti esperienze ed applicazioni di tali conoscenze. L'impostazione generale del presente lavoro, che sicuramente porta a trascurare alcuni aspetti particolari, per i quali si rimanda alla bibliografia, fornisce in ogni caso un quadro sintetico ed organico dello stato dell'arte dello studio della

UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6

Energy Technology Data Exchange (ETDEWEB)

Miyata, Maiko [Department of Life and Medical Sciences, Chubu University Faculty of Life and Health Sciences, Matsumoto, Kasugai 487-8501 (Japan); Department of Biochemistry II, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya 466-0065 (Japan); Ichihara, Masatoshi; Tajima, Orie; Sobue, Sayaka; Kambe, Mariko [Department of Life and Medical Sciences, Chubu University Faculty of Life and Health Sciences, Matsumoto, Kasugai 487-8501 (Japan); Sugiura, Kazumitsu [Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya 466-0065 (Japan); Furukawa, Koichi, E-mail: koichi@med.nagoya-u.ac.jp [Department of Biochemistry II, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya 466-0065 (Japan); Furukawa, Keiko [Department of Life and Medical Sciences, Chubu University Faculty of Life and Health Sciences, Matsumoto, Kasugai 487-8501 (Japan); Department of Biochemistry II, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya 466-0065 (Japan)

2014-03-07

Highlights: • Melanocytes showed low ST8SIA1 and high B3GALT4 levels in contrast with melanomas. • Direct UVB irradiation of melanocytes did not induce ganglioside synthase genes. • Culture supernatants of UVB-irradiated keratinocytes induced ST8SIA1 in melanocytes. • TNFα and IL-6 secreted from keratinocytes enhanced ST8SIA1 expression in melanocytes. • Inflammatory cytokines induced melanoma-related ST8SIA1 in melanocytes. - Abstract: Although expression of gangliosides and their synthetic enzyme genes in malignant melanomas has been well studied, that in normal melanocytes has been scarcely analyzed. In particular, changes in expression levels of glycosyltransferase genes responsible for ganglioside synthesis during evolution of melanomas from melanocytes are very important to understand roles of gangliosides in melanomas. Here, expression of glycosyltransferase genes related to the ganglioside synthesis was analyzed using RNAs from cultured melanocytes and melanoma cell lines. Quantitative RT-PCR revealed that melanomas expressed high levels of mRNA of GD3 synthase and GM2/GD2 synthase genes and low levels of GM1/GD1b synthase genes compared with melanocytes. As a representative exogenous stimulation, effects of ultraviolet B (UVB) on the expression levels of 3 major ganglioside synthase genes in melanocytes were analyzed. Although direct UVB irradiation of melanocytes caused no marked changes, culture supernatants of UVB-irradiated keratinocytes (HaCaT cells) induced definite up-regulation of GD3 synthase and GM2/GD2 synthase genes. Detailed examination of the supernatants revealed that inflammatory cytokines such as TNFα and IL-6 enhanced GD3 synthase gene expression. These results suggest that inflammatory cytokines secreted from UVB-irradiated keratinocytes induced melanoma-associated ganglioside synthase genes, proposing roles of skin microenvironment in the promotion of melanoma-like ganglioside profiles in melanocytes.

Progress Toward Poliomyelitis Eradication--Afghanistan, January 2014‒August 2015.

Science.gov (United States)

Mbaeyi, Chukwuma; Saatcioglu, Akif; Tangermann, Rudolf H; Hadler, Stephen; Ehrhardt, Derek

2015-10-23

Despite recent progress toward global polio eradication, endemic transmission of wild poliovirus (WPV) continues to be reported in Afghanistan and Pakistan. The Afghanistan program must overcome many challenges to remain on track toward achieving the objectives set in the 2013–2018 strategic plan of the Global Polio Eradication Initiative (GPEI). Cross-border transmission of WPV type 1 (WPV1) continues to occur among children traveling to and from Pakistan. The country's routine immunization system remains weak and unable to reach recommended benchmarks in most regions; hence, the national Polio Eradication Initiative (PEI) relies mainly on providing children aged <5 years with oral poliovirus vaccine (OPV), administered during supplementary immunization activities (SIAs). Because of ongoing conflict and insecurity, some children continue to be missed during SIAs in areas not under government control; however, the majority of missed children live in accessible areas and are often unreached because of a failure to plan, implement, and supervise SIAs efficiently. This report describes polio eradication activities and progress in Afghanistan during January 2014‒August 2015 and updates previous reports. During 2014, a total of 28 WPV1 cases were reported in Afghanistan, compared with 14 cases in 2013; nine cases were reported during January‒August 2015, the same number as during the same period in 2014. To eliminate poliovirus transmission in Afghanistan, emergency operations centers (EOCs) need to be established at the national level and in critical regions without delay to improve overall coordination and oversight of polio eradication activities. The recently revised National Emergency Action Plan for polio eradication needs to be fully implemented, including detailed microplanning and enhanced monitoring and supervision of SIAs, as well as improved cross-border coordination with Pakistan.

Coastal dynamics physical and mathematical modelling, territorial analysis, G.I.S. instrumentation. The state of the arts; La dinamica costiera modellistica fisico-matematica, analisi del territorio, il supporto G.I.S. e la strumentazione in uso

Energy Technology Data Exchange (ETDEWEB)

De Bonis, P.; Fattorusso, G.; Onori, F.; Pagano, A.; Pasanisi, F.; Peloso, A.; Regina, P.; Tebano, C.; Zarlenga, F. [ENEA, Div. Caratterizzazione dell' Ambiente, Centro Ricerche Casaccia, S. Maria di Galeria, Rome (Italy)

2001-07-01

The aim of the present work is to offer, in a single volume, the basic notions relative to different aspects, both theoretical and practical, of the study of coastal dynamical processes. It has been dealt with geological issues, physical and mathematical modelling, effects related to human activities, Geographical Information Systems as well as both laboratory and fields instrumentations. Reading this technical paper it has to keep in mind two aspects which have been authors guidelines. First of all, the research theme's have been studied on their theoretical aspects, focusing on the most recent developments. Then have been selected some up to date experiences and discuss their application. The general framework of this publication, which necessarily leave out some particular issues, for which the readers are to be referred to the references, gives a synthetic and homogenous picture of the state of the arts in coastal modelling. [Italian] Lo scopo della presente pubblicazione e' quello di offrire, in un unico volume, le nozioni di base riguardo ai diversi argomenti sia teorici sia pratici relativi all'analisi delle dinamiche costiere. Sono stati affrontati i temi relativi alla geologia, alla modellistica fisica e matematica, ai fattori di pressione antropica, all'utilizzo di Sistemi Informativi Geografici e alla strumentazione sia di campo sia di laboratorio. Nello sviluppo del presente Rapporto Tecnico si possono individuare per ciascuna delle aree di interesse due aspetti fondamentali. Dapprima i temi di ricerca sono stati studiati da un punto di vista teorico generale, con attenzione agli sviluppi piu' attuali e successivamente sono state presentate alcune recenti esperienze ed applicazioni di tali conoscenze. L'impostazione generale del presente lavoro, che sicuramente porta a trascurare alcuni aspetti particolari, per i quali si rimanda alla bibliografia, fornisce in ogni caso un quadro sintetico ed organico dello stato dell

UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6

International Nuclear Information System (INIS)

Miyata, Maiko; Ichihara, Masatoshi; Tajima, Orie; Sobue, Sayaka; Kambe, Mariko; Sugiura, Kazumitsu; Furukawa, Koichi; Furukawa, Keiko

2014-01-01

Highlights: • Melanocytes showed low ST8SIA1 and high B3GALT4 levels in contrast with melanomas. • Direct UVB irradiation of melanocytes did not induce ganglioside synthase genes. • Culture supernatants of UVB-irradiated keratinocytes induced ST8SIA1 in melanocytes. • TNFα and IL-6 secreted from keratinocytes enhanced ST8SIA1 expression in melanocytes. • Inflammatory cytokines induced melanoma-related ST8SIA1 in melanocytes. - Abstract: Although expression of gangliosides and their synthetic enzyme genes in malignant melanomas has been well studied, that in normal melanocytes has been scarcely analyzed. In particular, changes in expression levels of glycosyltransferase genes responsible for ganglioside synthesis during evolution of melanomas from melanocytes are very important to understand roles of gangliosides in melanomas. Here, expression of glycosyltransferase genes related to the ganglioside synthesis was analyzed using RNAs from cultured melanocytes and melanoma cell lines. Quantitative RT-PCR revealed that melanomas expressed high levels of mRNA of GD3 synthase and GM2/GD2 synthase genes and low levels of GM1/GD1b synthase genes compared with melanocytes. As a representative exogenous stimulation, effects of ultraviolet B (UVB) on the expression levels of 3 major ganglioside synthase genes in melanocytes were analyzed. Although direct UVB irradiation of melanocytes caused no marked changes, culture supernatants of UVB-irradiated keratinocytes (HaCaT cells) induced definite up-regulation of GD3 synthase and GM2/GD2 synthase genes. Detailed examination of the supernatants revealed that inflammatory cytokines such as TNFα and IL-6 enhanced GD3 synthase gene expression. These results suggest that inflammatory cytokines secreted from UVB-irradiated keratinocytes induced melanoma-associated ganglioside synthase genes, proposing roles of skin microenvironment in the promotion of melanoma-like ganglioside profiles in melanocytes

Validación de la Escala de ansiedad en la interacción social en estudiantes universitarios mexicanos

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José Moral de la Rubia

2013-01-01

Full Text Available Objetivo. El propósito de esta investigación fue validar la escala de ansiedad en la interacción social (Social Interaction Anxiety Scale [SIAS-20] de Mattick y Clarke, 1998 en una población de estudiantes universitarios mexicanos. Concretamente, se buscó validar la estructura unidimensional del SIAS-20, calcular su consistencia interna, describir su distribución, comparar diferencias de medias entre géneros, comprobar su validez criterial con el factor de fobia social del inventario de ansiedad y fobia social (Social Phobia and Anxiety Inventory [SPAI] de Turner, Beidel, Dancu y Stanley, 1989 y su validez convergente con la escala de autoverbalizaciones al hablar en público (Self-Statements during Public Speaking Scale [SSPS] de Hofmann y DiBartolo, 2000 así como estudiar su relación con un inventario de deseabilidad social (Balanced Inventory of Desirable Responding [BIDR] de Paulhus, 1998. Método. Para ello, se empleó una muestra probabilística de estudiantes universitarios, estratificada por genéros. Resultados. Descartados los tres ítems inversos del SIAS-20, el modelo unidimensional tuvo buen ajuste. Además, la consistencia interna del SIAS-17 fue alta y su distribución asimétrica positiva. Los promedios fueron estadísticamente equivalentes entre ambos genéros. La escala mostró validez criterial con el SPAI y convergente con el SSPS. La correlación con deseabilidad social fue baja. Conclusión. Se encontró que la escala es válida para emplearla con población estudiantil universitaria mexicana. Futuros estudios deben concentrarse en su estandarización por percentiles, tanto en población mexicana, como en países hispanoparlantes.

Monitoraggio della biodiversità in relazione all’applicazione degli standard di condizionalità: 4.2c, 4.6, 4.3 (olivo

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Claudia Corti

2016-02-01

Full Text Available Nel presente lavoro vengono riportati i risultati relativi ai monitoraggi della diversità faunistica per i seguenti standard: 4.2c, 4.3 (olivo, 4.6. I risultati ottenuti sono nel complesso interessanti sia dal punto di vista metodologico sia per quanto concerne gli aspetti conservazionistici e gestionali. Emerge l’importanza di utilizzare più indicatori o gruppi tassonomici che comprendano taxa ecologicamente e funzionalmente diversi per valutare la “biodiversità”. Relativamente allo sfalcio è stato osservato che una “blanda gestione” dei ritirati dalla produzione può favorire un certo incremento di biodiversità sia per quanto riguarda gli Artropodi, sia per quanto riguarda i Rettili. Risultati concordi sono stati osservati anche negli oliveti dove la gestione della vegetazione al suolo (sfalcio sembrerebbe incrementare la diversità. Tuttavia è opportuno ricordare che l’effetto monitorato, almeno nei ritirati dalla produzione, non è quello immediatamente successivo all’azione meccanica che invece provoca danni diretti e immediati alla fauna (ferimento e uccisione. Emerge con evidenza dai dati raccolti anche l’importanza della presenza, all’interno degli agro-ecosistemi, di aree a minor disturbo antropico, naturali e semi-naturali: fasce ecotonali e ripariali, ma anche bordure dei campi. Viceversa l’uniformità del paesaggio e la presenza di grandi estensioni coltivate a monocoltura rappresentano elementi sfavorevoli alla biodiversità animale. Nel monitoraggio attraverso l’utilizzo della tecnica di fototrappolaggio è emersa l’importante funzione svolta dai muretti a secco, “presenze” tipiche e diffuse nel paesaggio agricolo tradizionale del nostro territorio italiano. Per molti taxa animali detti manufatti assolvono a funzioni ecologiche diverse, quali: rifugio, aree di foraggiamento, passaggio o sosta nonché punti ottimali per la termoregolazione.

Tumor Targeting via Sialic Acid: [68Ga]DOTA-en-pba as a New Tool for Molecular Imaging of Cancer with PET.

Science.gov (United States)

Tsoukalas, Charalambos; Geninatti-Crich, Simonetta; Gaitanis, Anastasios; Tsotakos, Theodoros; Paravatou-Petsotas, Maria; Aime, Silvio; Jiménez-Juárez, Rogelio; Anagnostopoulos, Constantinos D; Djanashvili, Kristina; Bouziotis, Penelope

2018-02-20

The aim of this study was to demonstrate the potential of Ga-68-labeled macrocycle (DOTA-en-pba) conjugated with phenylboronic vector for tumor recognition by positron emission tomography (PET), based on targeting of the overexpressed sialic acid (Sia). The imaging reporter DOTA-en-pba was synthesized and labeled with Ga-68 at high efficiency. Cell binding assay on Mel-C and B16-F10 melanoma cells was used to evaluate melanin production and Sia overexpression to determine the best model for demonstrating the capability of [ 68 Ga]DOTA-en-pba to recognize tumors. The in vivo PET imaging was done with B16-F10 tumor-bearing SCID mice injected with [ 68 Ga]DOTA-en-pba intravenously. Tumor, blood, and urine metabolites were assessed to evaluate the presence of a targeting agent. The affinity of [ 68 Ga]DOTA-en-pba to Sia was demonstrated on B16-F10 melanoma cells, after the production of melanin as well as Sia overexpression was proved to be up to four times higher in this cell line compared to that in Mel-C cells. Biodistribution studies in B16-F10 tumor-bearing SCID mice showed blood clearance at the time points studied, while uptake in the tumor peaked at 60 min post-injection (6.36 ± 2.41 % ID/g). The acquired PET images were in accordance with the ex vivo biodistribution results. Metabolite assessment on tumor, blood, and urine samples showed that [ 68 Ga]DOTA-en-pba remains unmetabolized up to at least 60 min post-injection. Our work is the first attempt for in vivo imaging of cancer by targeting overexpression of sialic acid on cancer cells with a radiotracer in PET.

Hormonal and molecular effects of restraint stress on formalin-induced pain-like behavior in male and female mice.

Science.gov (United States)

Long, Caela C; Sadler, Katelyn E; Kolber, Benedict J

2016-10-15

The evolutionary advantages to the suppression of pain during a stressful event (stress-induced analgesia (SIA)) are obvious, yet the reasoning behind sex-differences in the expression of this pain reduction are not. The different ways in which males and females integrate physiological stress responses and descending pain inhibition are unclear. A potential supraspinal modulator of stress-induced analgesia is the central nucleus of the amygdala (CeA). This limbic brain region is involved in both the processing of stress and pain; the CeA is anatomically and molecularly linked to regions of the hypothalamic pituitary adrenal (HPA) axis and descending pain network. The CeA exhibits sex-based differences in response to stress and pain that may differentially induce SIA in males and females. Here, sex-based differences in behavioral and molecular indices of SIA were examined following noxious stimulation. Acute restraint stress in male and female mice was performed prior to intraplantar injections of formalin, a noxious inflammatory agent. Spontaneous pain-like behaviors were measured for 60min following formalin injection and mechanical hypersensitivity was evaluated 120 and 180min post-injection. Restraint stress altered formalin-induced spontaneous behaviors in male and female mice and formalin-induced mechanical hypersensitivity in male mice. To assess molecular indices of SIA, tissue samples from the CeA and blood samples were collected at the 180min time point. Restraint stress prevented formalin-induced increases in extracellular signal regulated kinase 2 (ERK2) phosphorylation in the male CeA, but no changes associated with pERK2 were seen with formalin or restraint in females. Sex differences were also seen in plasma corticosterone concentrations 180min post injection. These results demonstrate sex-based differences in behavioral, molecular, and hormonal indices of acute stress in mice that extend for 180min after stress and noxious stimulation. Copyright �

PERANCANGAN INTEGRASI SISTEM INFORMASI AKADEMIK DENGAN E-LEARNING (Studi Kasus : Program Studi XYZ

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Brav Deva Bernadhi

2017-01-01

ABSTRACT   Growth of access to information at the present time is running fast. Public or the user to obtain data or information that is accurate, current, and a quick and easy right now is not difficult. The development of the Internet in today's increasingly rapidly and can not be separated from the world of education. Presence information systems and the Internet continues to grow, then created a way of delivering education electronically with the help of internet. The information system is at present better known as electronic learning (e-learning. E-learning is an information system that helps instructional manual to electronic learning. In the world of education to enable faculty and students to manage course, nowadays there are more Academic Information System shortened by SIA. SIA is an information system that manages and processes all the data of academic residing in the academic field. KRS SIA online that are closely related to the subjects that will be filled in e-learning. From the view of these needs, it helps both information systems are combined so that the user fills in SIA, the e-learning systems relating to subjects who follow will update itself and needs to be designed so that both the information system can run well and can used by the user. Ergonomic approach is needed for these systems is the Human Computer Interaction (HCI so that the developed system will be convenient, easy and safe to use by the user, or in             other words is user friendly. These journals are intended to develop a system AIS integration with e-learning in order to assist and facilitate the activities of learning in Higher Education.

Food web functioning of the benthopelagic community in a deep-sea seamount based on diet and stable isotope analyses

Science.gov (United States)

Preciado, Izaskun; Cartes, Joan E.; Punzón, Antonio; Frutos, Inmaculada; López-López, Lucía; Serrano, Alberto

2017-03-01

Trophic interactions in the deep-sea fish community of the Galicia Bank seamount (NE Atlantic) were inferred by using stomach contents analyses (SCA) and stable isotope analyses (SIA) of 27 fish species and their main prey items. Samples were collected during three surveys performed in 2009, 2010 and 2011 between 625 and 1800 m depth. Three main trophic guilds were determined using SCA data: pelagic, benthopelagic and benthic feeders, respectively. Vertically migrating macrozooplankton and meso-bathypelagic shrimps were identified to play a key role as pelagic prey for the deep sea fish community of the Galicia Bank. Habitat overlap was hardly detected; as a matter of fact, when species coexisted most of them evidenced a low dietary overlap, indicating a high degree of resource partitioning. A high potential competition, however, was observed among benthopelagic feeders, i.e.: Etmopterus spinax, Hoplostethus mediterraneus and Epigonus telescopus. A significant correlation was found between δ15N and δ13C for all the analysed species. When calculating Trophic Levels (TLs) for the main fish species, using both the SCA and SIA approaches, some discrepancies arose: TLs calculated from SIA were significantly higher than those obtained from SCA, probably indicating a higher consumption of benthic-suprabenthic prey in the previous months. During the summer, food web functioning in the Galicia Bank was more influenced by the assemblages dwelling in the water column than by deep-sea benthos, which was rather scarce in the summer samples. These discrepancies demonstrate the importance of using both approaches, SCA (snapshot of diet) and SIA (assimilated food in previous months), when attempting trophic studies, if an overview of food web dynamics in different compartments of the ecosystem is to be obtained.

Boots of Leather, Slippers of Gold: The History of a Lesbian Community

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Maria Chiara Ferro

2016-03-01

Full Text Available Elizabeth Lapovsky Kennedy, Madeline D. Davis, Boots of Leather, Slippers of Gold: The History of a Lesbian Community (1993. New York: Routledge, 2014.   La recensione sottolinea la rilevanza del volume Boots of Leather, Slippers of Gold a vent’anni dalla pubblicazione, sia perché raccoglie e preserva testimonianze di butches e femmes degli anni ’40 e ’50, sia perché chiarisce il ruolo sociale della comunità butch-femme in quanto sede di resistenza pre-politica. Inoltre, si evidenzia l’utilità di modelli interpretativi informati dagli studi queer e transgender nell’ambito della ricerca storica su identità non normative come quelle butch e femme.

I nomi delle feste mariane nelle lungue slave

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Fedora Ferluga-Petronio

1981-12-01

Full Text Available Nell'articolo l'autrice traccia un' analisi lessicale ed etimologioa delle feste Mariana nelle lingua slave.Vengono prese in considerazione tre fra, le principali feste di Ma­ rla, tuttora celebrate sia dalla Ohiesa cattolica sia dalla Ohiesa ortodossa: l'Annunciazione, l'Assunzione, la Nascita di Maria.L'Immacolata Concezione, festa comandata presso i cattolici, e la Presentazione di Maria al Tempio, una delle dodici grandi feste ortodosse, sono meno interessanti dal punto di vista linguistico, in quanto semplioemente calchi del le denominazioni mfficiali latina e greche. Per le singole feste viene tracciata anche una breve introduzione storica, onde poter meglio capire l'origine ed a volte l' etimo dei termini in questione.

Introduction. The development of the book market and book collecting in the sixteenth century

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Giovanna Granata

2018-05-01

Full Text Available Il convegno “Selling and collecting: printed book sale catalogues and private libraries in early modern Europe”, tenutosi a Cagliari nel settembre 2017, ha costituito l’occasione per presentare a livello internazionale alcuni tra i più rilevanti progetti e ricerche inerenti le modalità di vendita e acquisto, di collezione e circolazione del libro nel corso del XVI secolo. L’articolo espone brevemente le tematiche maggiormente rilevanti del convegno, riconducibili a due grandi ambiti: il commercio librario, indagato nei suoi aspetti più prettamente economici, e il collezionismo privato, inteso sia come espressione degli interessi culturali dell’epoca sia come elemento indicativo degli intensi rapporti tra acquirenti e venditori.

Social impact assessment: A review and proposed approach: Final report

International Nuclear Information System (INIS)

Bradbury, J.A.

1986-12-01

The objective of the report is to identify the essential components of a comprehensive plan to assess the potential social impacts of the proposed construction and operation of a high level radioactive waste repository by the Nevada Nuclear Waste Storage Investigations (NNWSI) Project. The tasks taken to achieve this objective are: examination of the literature on Social Impact Assessment (SIA); identification of different conceptual frameworks that have been proposed or used in SIA; examination of specific aspects of the frameworks; assessment of strengths and weaknesses of the frameworks; synthesis of common elements in these frameworks; and examination and evaluation of methods of data collection and analysis. 150 refs., 6 figs., 7 tabs

Dalla geometria delle preesistenze alla conoscenza della costruzione: un’esperienza di recupero aggiornata dalla metodologia BIM

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Massimiliano Lo Turco

2012-06-01

Full Text Available Il termine costruire (lessicalmente equivale a riordinare le singole parti dell’operazione secondo il nesso logico e grammaticale; ed altresì disporle e collegarle secondo le regole e l’uso della lingua. Analogamente gli odierni strumenti BIM possiedono nelle loro corde sia una riconoscibile capacità di sviluppare progetti seguendo le regole del buon costruire, sia un puntuale controllo della geometria da cui derivano le molteplici rappresentazioni di tipo grafo-numerico. Ci si interrogherà inoltre sul rinnovato rapporto tra Rilievo e Progetto, in un ambiente particolarmente fertile ove la Geometria è indagata nelle sue poliedriche proprietà e al Disegno è affidato un ruolo di maggiore visibilità e di effettiva rilevanza.

Social impact assessment: A review and proposed approach: Final report

Energy Technology Data Exchange (ETDEWEB)

Bradbury, J A

1986-12-01

The objective of the report is to identify the essential components of a comprehensive plan to assess the potential social impacts of the proposed construction and operation of a high level radioactive waste repository by the Nevada Nuclear Waste Storage Investigations (NNWSI) Project. The tasks taken to achieve this objective are: examination of the literature on Social Impact Assessment (SIA); identification of different conceptual frameworks that have been proposed or used in SIA; examination of specific aspects of the frameworks; assessment of strengths and weaknesses of the frameworks; synthesis of common elements in these frameworks; and examination and evaluation of methods of data collection and analysis. 150 refs., 6 figs., 7 tabs.

The inherent dangers of using computable general equilibrium models as a single integrated modelling framework for sustainability impact assessment. A critical note on Boehringer and Loeschel (2006)

International Nuclear Information System (INIS)

Scrieciu, S. Serban

2007-01-01

The search for methods of assessment that best evaluate and integrate the trade-offs and interactions between the economic, environmental and social components of development has been receiving a new impetus due to the requirement that sustainability concerns be incorporated into the policy formulation process. A paper forthcoming in Ecological Economics (Boehringer, C., Loeschel, A., in press. Computable general equilibrium models for sustainability impact assessment: status quo and prospects, Ecological Economics.) claims that Computable General Equilibrium (CGE) models may potentially represent the much needed 'back-bone' tool to carry out reliable integrated quantitative Sustainability Impact Assessments (SIAs). While acknowledging the usefulness of CGE models for some dimensions of SIA, this commentary questions the legitimacy of employing this particular economic modelling tool as a single integrating modelling framework for a comprehensive evaluation of the multi-dimensional, dynamic and complex interactions between policy and sustainability. It discusses several inherent dangers associated with the advocated prospects for the CGE modelling approach to contribute to comprehensive and reliable sustainability impact assessments. The paper warns that this reductionist viewpoint may seriously infringe upon the basic values underpinning the SIA process, namely a transparent, heterogeneous, balanced, inter-disciplinary, consultative and participatory take to policy evaluation and building of the evidence-base. (author)

Marsiglia, una terra a Sud di nessun nord. La presenza dei gruppi criminali nella ville méditerranée

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Rosaria Anghelone

2015-07-01

Full Text Available Il lavoro si propone di affrontare la presenza dei gruppi criminali a Marsiglia, dagli anni delle grandi migrazioni di inizio secolo scorso, in cui il porto Mediterraneo è stato il cuore di scambi commerciali e culturali, sino agli anni recenti, in cui la città ha tirato fuori, costruendola, la sua faccia europea. Lungo tutto quest’arco temporale, confronteremo le vicende e le figure che emergeranno nel contesto, che si determinerà di fase in fase, con la concettualizzazione del fenomeno mafioso italiano; quest’ultima, come cartina al tornasole, ci permetterà di cogliere le caratteristiche del milieu marsigliese, i suoi tratti specifici e quelli che lo accomunano, sia nella logica che nell’esplicazione del suo potere, alla mafia. Marsiglia, incarnando tutte le contraddizioni delle terre del Sud, farà da palcoscenico per la riflessione sui fattori che favoriscono la nascita e rafforzano la crescita dei gruppi criminali. L’intento, oltre l’analisi del singolo caso marsigliese, è, altresì, quello di constatare quanto la Francia sia ancora impreparata in tema di contrasto alla criminalità organizzata di stampo mafioso, sottovalutandone gli effetti, e quanto, ancor di più, sia ormai imprescindibile un intervento europeo su questo versante, tendente all’armonizzazione delle legislazioni nazionali.

Sensitivity of decadal predictions to the initial atmospheric and oceanic perturbations

Energy Technology Data Exchange (ETDEWEB)

Du, H.; Garcia-Serrano, J.; Guemas, V.; Soufflet, Y. [Institut Catala de Ciencies del Clima (IC3), Barcelona (Spain); Doblas-Reyes, F.J. [Institut Catala de Ciencies del Clima (IC3), Barcelona (Spain); Institucio Catalana de Recerca i Estudis Avancats (ICREA), Barcelona (Spain); Wouters, B. [Royal Netherlands Meteorological Institute (KNMI), De Bilt (Netherlands)

2012-10-15

A coupled global atmosphere-ocean model is employed to investigate the impact of initial perturbation methods on the behaviour of five-member ensemble decadal re-forecasts. Three initial-condition perturbation strategies, atmosphere only, ocean only and atmosphere-ocean, have been used and the impact on selected variables have been investigated. The impact has been assessed in terms of climate drift, forecast quality and spread. The simulated global means of near-surface air temperature (T2M), sea surface temperature (SST) and sea ice area (SIA) for both Arctic and Antarctic show reasonably good quality, in spite of the non-negligible drift of the model. The skill in terms of correlation is not significantly affected by the particular perturbation method employed. The ensemble spread generated for T2M, SST and land surface precipitation (PCP) saturates quickly with any of the perturbation methods. However, for SIA, Atlantic meridional overturning circulation (AMOC) and ocean heat content (OHC), the spread increases substantially during the forecast time when ocean perturbations are applied. Ocean perturbations are particularly important for Antarctic SIA and OHC for the middle and deep layers of the ocean. The results will be helpful in the design of ensemble prediction experiments. (orig.)

Generalized Rate Theory for Void and Bubble Swelling and its Application to Plutonium Metal Alloys

Energy Technology Data Exchange (ETDEWEB)

Allen, P. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wolfer, W. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2015-10-16

In the classical rate theory for void swelling, vacancies and self-interstitials are produced by radiation in equal numbers, and in addition, thermal vacancies are also generated at the sinks, primarily at edge dislocations, at voids, and at grain boundaries. In contrast, due to the high formation energy of self-interstitials for normal metals and alloys, their thermal generation is negligible, as pointed out by Bullough and Perrin. However, recent DFT calculations of the formation energy of self-interstitial atoms in bcc metals have revealed that the sum of formation and migration energies for self-interstitials atoms (SIA) is of the same order of magnitude as for vacancies. The ratio of the activation energies for thermal generation of SIA and vacancies is presented. For fcc metals, this ratio is around three, but for bcc metals it is around 1.5. Reviewing theoretical predictions of point defect properties in δ-Pu, this ratio could possibly be less than one. As a result, thermal generation of SIA in bcc metals and in plutonium must be taken into considerations when modeling the growth of voids and of helium bubbles, and the classical rate theory (CRT) for void and bubble swelling must be extended to a generalized rate theory (GRT).

Surgically induced astigmatism after 3.0 mm temporal and nasal clear corneal incisions in bilateral cataract surgery

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Je Hwan Yoon

2013-01-01

Full Text Available Aims: To compare the corneal refractive changes induced after 3.0 mm temporal and nasal corneal incisions in bilateral cataract surgery. Materials and Methods: This prospective study comprised a consecutive case series of 60 eyes from 30 patients with bilateral phacoemulsification that were implanted with a 6.0 mm foldable intraocular lens through a 3.0 mm horizontal clear corneal incision (temporal in the right eyes, nasal in the left eyes. The outcome measures were surgically induced astigmatism (SIA and uncorrected visual acuity (UCVA 1 and 3 months, post-operatively. Results: At 1 month, the mean SIA was 0.81 diopter (D for the temporal incisions and 0.92 D for nasal incisions (P = 0.139. At 3 months, the mean SIA were 0.53 D for temporal incisions and 0.62 D for nasal incisions (P = 0.309. The UCVA was similar in the 2 incision groups before surgery, and at 1 and 3 months post-operatively. Conclusion: After bilateral cataract surgery using 3.0 mm temporal and nasal horizontal corneal incisions, the induced corneal astigmatic change was similar in both incision groups. Especially in Asian eyes, both temporal and nasal incisions (3.0 mm or less would be favorable for astigmatism-neutral cataract surgery.

Fold-recognition and comparative modeling of human α2,3-sialyltransferases reveal their sequence and structural similarities to CstII from Campylobacter jejuni

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Balaji Petety V

2006-04-01

Full Text Available Abstract Background The 3-D structure of none of the eukaryotic sialyltransferases (SiaTs has been determined so far. Sequence alignment algorithms such as BLAST and PSI-BLAST could not detect a homolog of these enzymes from the protein databank. SiaTs, thus, belong to the hard/medium target category in the CASP experiments. The objective of the current work is to model the 3-D structures of human SiaTs which transfer the sialic acid in α2,3-linkage viz., ST3Gal I, II, III, IV, V, and VI, using fold-recognition and comparative modeling methods. The pair-wise sequence similarity among these six enzymes ranges from 41 to 63%. Results Unlike the sequence similarity servers, fold-recognition servers identified CstII, a α2,3/8 dual-activity SiaT from Campylobacter jejuni as the homolog of all the six ST3Gals; the level of sequence similarity between CstII and ST3Gals is only 15–20% and the similarity is restricted to well-characterized motif regions of ST3Gals. Deriving template-target sequence alignments for the entire ST3Gal sequence was not straightforward: the fold-recognition servers could not find a template for the region preceding the L-motif and that between the L- and S-motifs. Multiple structural templates were identified to model these regions and template identification-modeling-evaluation had to be performed iteratively to choose the most appropriate templates. The modeled structures have acceptable stereochemical properties and are also able to provide qualitative rationalizations for some of the site-directed mutagenesis results reported in literature. Apart from the predicted models, an unexpected but valuable finding from this study is the sequential and structural relatedness of family GT42 and family GT29 SiaTs. Conclusion The modeled 3-D structures can be used for docking and other modeling studies and for the rational identification of residues to be mutated to impart desired properties such as altered stability, substrate

Ações de vigilância sanitária no município de Divinópolis, Minas Gerais, entre 2008 e 2013 / Actions of health surveillance in southeast brazilian city from 2008 to 2013

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Suelen Garcia Oliveira da Fonseca

2014-02-01

Full Text Available Os municípios brasileiros apresentam modalidades distintas de organização e gestão pública em virtude das diferentes realidades regionais, o que constitui uma importante estratégia para o planejamento dos serviços de vigilância sanitária. O objetivo deste estudo é descrever e analisar os procedimentos realizados pela Vigilância Sanitária do município de Divinópolis inserido no Sistema de Informações Ambulatoriais (SIA-SUS entre 2008 e 2013. Trata-se de um estudo transversal que utilizou informações do banco de dados eletrônico SIA-SUS e disponibilizado de forma pública através do site DATA/SUS. A partir do Tabnet/Datasus foram acessados os dados da produção ambulatorial do SUS por local de atendimento e forma de organização referente à vigilância sanitária. As informações foram exportadas e organizadas por tipo de atividade para o programa computacional Windows Excel® (versão 2007 para análise descritiva dos dados. De um total de 49 tipos de procedimentos executados pela vigilância sanitária de Divinópolis, 6 (12,24% são relativos a processo administrativo sanitário, 4 (8,16% às atividades educativas, 5 (10,20% são relativos à análise/investigação de surtos e 10 (20,41% à inspeção sanitária. O SIA-SUS é uma ferramenta útil para o desenvolvimento de mecanismos de avaliação do serviço de vigilância sanitária. --------------------------------------------------------------------------- The Brazilian municipalities have distinct modes of organization and public administration owing to differing regional realities, which is an important strategy for the planning of he-alth surveillance services. The aim of this study is to describe and analyse the procedures performed by the Health Surveillance service of Divinópolis inserted into the Ambulatory Information System (SIA-SUS from 2008 to 2013. This was a cross-sectional study that used information from the electronic database SIA-SUS and publicly

Defect accumulation under cascade damage conditions

DEFF Research Database (Denmark)

Trinkaus, H.; Singh, B.N.; Woo, C.H.

1994-01-01

in terms of this reaction kinetics taking into account cluster production, dissociation, migration and annihilation at extended sinks. Microstructural features which are characteristic of cascade damage and cannot be explained in terms of the conventional single defect reaction kinetics are emphasized......There is now ample evidence from both experimental and computer simulation studies that in displacement cascades not only intense recombination takes place but also efficient clustering of both self-interstitial atoms (SIAs) and vacancies. The size distributions of the two types of defects produced...... reactions kinetics associated with the specific features of cascade damage is described, with emphasis on asymmetries between SIA and vacancy type defects concerning their production, stability, mobility and interactions with other defects. Defect accumulation under cascade damage conditions is discussed...

Territorio e logistica: un binomio ancora tutto da inventare

Directory of Open Access Journals (Sweden)

Alessandro Bove

2008-12-01

Full Text Available La velocità di adattamento alle situazioni è quel concetto che sta alla base del nuovo modo di fare e vivere il territorio. Esso accomuna sia gli aspetti di urgenza legati all’esigenza di trasformazione delle strutture territoriali per far sì che esse possano confrontarsi in maniera competitiva con territori che sempre di più devono aggiornare la propria immagine ed organizzazione per far fronte ai nuovi dettami e strategie imposti dalla globalizzazione, sia gli aspetti più strettamente economici e della produzione i quali, nelle sfide lanciate dalla mondializzazione dei mercati e dall’impellenza della sostenibilità - intesa nella sua accezione più ampia - risentono in maniera sempre più pressante della necessità di un aggiornamento o di una trasformazione continui.

Mechanism of vacancy formation induced by hydrogen in tungsten

Directory of Open Access Journals (Sweden)

Yi-Nan Liu

2013-12-01

Full Text Available We report a hydrogen induced vacancy formation mechanism in tungsten based on classical molecular dynamics simulations. We demonstrate the vacancy formation in tungsten due to the presence of hydrogen associated directly with a stable hexagonal self-interstitial cluster as well as a linear crowdion. The stability of different self-interstitial structures has been further studied and it is particularly shown that hydrogen plays a crucial role in determining the configuration of SIAs, in which the hexagonal cluster structure is preferred. Energetic analysis has been carried out to prove that the formation of SIA clusters facilitates the formation of vacancies. Such a mechanism contributes to the understanding of the early stage of the hydrogen blistering in tungsten under a fusion reactor environment.

Fassaadi viimistlusvead kinni nii teadmatuses kui ka hoolimatuses / Eneken Laasme

Index Scriptorium Estoniae

Laasme, Eneken

2006-01-01

Viimistlusvigade tagajärjeks on hoone konstruktiivse osa lagunemine ning sise- ja välisseinte hallitus. Kommenteerivad SIA Caparol Baltica Eesti filiaali juhataja Jaan Vikat ja Heiki Tuisk OÜ Värvikeskuste Grupist

Elastic fields, dipole tensors, and interaction between self-interstitial atom defects in bcc transition metals

Science.gov (United States)

Dudarev, S. L.; Ma, Pui-Wai

2018-03-01

Density functional theory (DFT) calculations show that self-interstitial atom (SIA) defects in nonmagnetic body-centered-cubic (bcc) metals adopt strongly anisotropic configurations, elongated in the direction [S. Han et al., Phys. Rev. B 66, 220101 (2002), 10.1103/PhysRevB.66.220101; D. Nguyen-Manh et al., Phys. Rev. B 73, 020101 (2006), 10.1103/PhysRevB.73.020101; P. M. Derlet et al., Phys. Rev. B 76, 054107 (2007), 10.1103/PhysRevB.76.054107; S. L. Dudarev, Annu. Rev. Mater. Res. 43, 35 (2013), 10.1146/annurev-matsci-071312-121626]. Elastic distortions, associated with such anisotropic atomic structures, appear similar to distortions around small prismatic dislocation loops, although the extent of this similarity has never been quantified. We derive analytical formulas for the dipole tensors of SIA defects, which show that, in addition to the prismatic dislocation looplike character, the elastic field of a SIA defect also has a significant isotropic dilatation component. Using empirical potentials and DFT calculations, we parametrize dipole tensors of defects for all the nonmagnetic bcc transition metals. This enables a quantitative evaluation of the energy of elastic interaction between the defects, which also shows that in a periodic three-dimensional simple cubic arrangement of crowdions, long-range elastic interactions between a defect and all its images favor a orientation of the defect.

Integrating stomach content and stable isotope analyses to quantify the diets of pygoscelid penguins.

Directory of Open Access Journals (Sweden)

Michael J Polito

Full Text Available Stomach content analysis (SCA and more recently stable isotope analysis (SIA integrated with isotopic mixing models have become common methods for dietary studies and provide insight into the foraging ecology of seabirds. However, both methods have drawbacks and biases that may result in difficulties in quantifying inter-annual and species-specific differences in diets. We used these two methods to simultaneously quantify the chick-rearing diet of Chinstrap (Pygoscelis antarctica and Gentoo (P. papua penguins and highlight methods of integrating SCA data to increase accuracy of diet composition estimates using SIA. SCA biomass estimates were highly variable and underestimated the importance of soft-bodied prey such as fish. Two-source, isotopic mixing model predictions were less variable and identified inter-annual and species-specific differences in the relative amounts of fish and krill in penguin diets not readily apparent using SCA. In contrast, multi-source isotopic mixing models had difficulty estimating the dietary contribution of fish species occupying similar trophic levels without refinement using SCA-derived otolith data. Overall, our ability to track inter-annual and species-specific differences in penguin diets using SIA was enhanced by integrating SCA data to isotopic mixing modes in three ways: 1 selecting appropriate prey sources, 2 weighting combinations of isotopically similar prey in two-source mixing models and 3 refining predicted contributions of isotopically similar prey in multi-source models.

Immunochemical studies and genetic background of two Neisseria meningitidis isolates expressing unusual capsule polysaccharide antigens with specificities of both serogroup Y and W135.

Science.gov (United States)

Tsang, Raymond S W; Tsai, Chao Ming; Henderson, Averil M; Tyler, Shaun; Law, Dennis K S; Zollinger, Wendell; Jamieson, Frances

2008-03-01

We described 2 unusual Neisseria meningitidis strains isolated from epidemiologically unrelated invasive meningococcal disease cases in Ontario, Canada. Both isolates have features typical of serogroup Y N. meningitidis: are of serotype 2c, are of the multi-locus sequence types typical of the serogroup Y strains in Canada, and are genotyped as serogroup Y based on a previously described PCR-ELISA method that detects the serogroup-Y-specific siaD gene. However, both strains were poly-agglutinable in both anti-Y and anti-W135 antisera. Further studies on 1 of these 2 isolates showed the presence of glucose and galactose as well as sialic acids in its purified capsular polysaccharide, suggesting the presence of both serogroup Y and serogroup W135 polysaccharides. Rabbit antisera produced to this strain contained antibodies to both purified serogroup Y and serogroup W135 capsular polysaccharides. Absorption experiments with either serogroup Y or serogroup W135 bacteria confirmed the presence of antibodies to these 2 different polysaccharides. DNA sequencing of the cps operon from both isolates revealed a siaD gene with 99.7% homology to the published siaD sequence from a serogroup Y strain but with 3 point mutations that all resulted in amino acid changes. How these strains may affect results of routine surveillance, PCR diagnosis, and immuno-protection by vaccination are discussed.

The energy and stability of helium-related cluster in nickel: A study of molecular dynamics simulation

Energy Technology Data Exchange (ETDEWEB)

Gong, Hengfeng, E-mail: gonghengfeng@sinap.ac.cn [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Division of Nuclear Materials and Engineering, Shanghai 201800 (China); Key Laboratory of Interfacial Physics and Technology, Chinese Academy of Sciences, Shanghai 201800 (China); Wang, Chengbin; Zhang, Wei; Xu, Jian [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Division of Nuclear Materials and Engineering, Shanghai 201800 (China); Key Laboratory of Interfacial Physics and Technology, Chinese Academy of Sciences, Shanghai 201800 (China); Huai, Ping, E-mail: huaiping@sinap.ac.cn [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Division of Nuclear Materials and Engineering, Shanghai 201800 (China); Key Laboratory of Nuclear Radiation and Nuclear Energy Technology, Chinese Academy of Sciences, Shanghai 201800 (China); Deng, Huiqiu; Hu, Wangyu [Hunan University, Department of Applied Physics, Changsha 410082 (China)

2016-02-01

Highlights: • The He-related clusters exhibit the very high symmetry. • The trapping capability of vacancy to defects becomes weak due to the pre-existed SIA. • The average length of He{sub N}V{sub 1} clusters is longer than one of He{sub N} and He{sub N}V{sub 1}SIA{sub 1} cluster. - Abstract: Using molecular dynamics simulation, we investigated the energy and stability of helium-related cluster in nickel. All the binding energies of the He-related clusters are demonstrated to be positive and increase with the cluster sizes. Due to the pre-existed self-interstitial nickel atom, the trapping capability of vacancy to defects becomes weak. Besides, the minimum energy configurations of He-related clusters exhibit the very high symmetry in the local atomistic environment. And for the He{sub N} and He{sub N}V{sub 1}SIA{sub 1} clusters, the average length of He–He bonds shortens, but it elongates for the He{sub N}V{sub 1} clusters with helium cluster sizes. The helium-to-vacancy ratio plays a decisive role on the binding energies of He{sub N}V{sub M} cluster. These results can provide some excellent clues to insight the initial stage of helium bubbles nucleation and growth in the Ni-based alloys for the Generation-IV Molten Salt Reactor.

Cognitive and physical functions related to the level of supervision and dependence in the toileting of stroke patients.

Science.gov (United States)

Sato, Atsushi; Okuda, Yutaka; Fujita, Takaaki; Kimura, Norihiko; Hoshina, Noriyuki; Kato, Sayaka; Tanaka, Shigenari

2016-01-01

This study aimed to clarify which cognitive and physical factors are associated with the need for toileting assistance in stroke patients and to calculate cut-off values for discriminating between independent supervision and dependent toileting ability. This cross-sectional study included 163 first-stroke patients in nine convalescent rehabilitation wards. Based on their FIM Ⓡ instrument score for toileting, the patients were divided into an independent-supervision group and a dependent group. Multiple logistic regression analysis and receiver operating characteristic analysis were performed to identify factors related to toileting performance. The Minimental State Examination (MMSE); the Stroke Impairment Assessment Set (SIAS) score for the affected lower limb, speech, and visuospatial functions; and the Functional Assessment for Control of Trunk (FACT) were analyzed as independent variables. The multiple logistic regression analysis showed that the FIM Ⓡ instrument score for toileting was associated with the SIAS score for the affected lower limb function, MMSE, and FACT. On receiver operating characteristic analysis, the SIAS score for the affected lower limb function cut-off value was 8/7 points, the MMSE cut-off value was 25/24 points, and the FACT cut-off value was 14/13 points. Affected lower limb function, cognitive function, and trunk function were related with the need for toileting assistance. These cut-off values may be useful for judging whether toileting assistance is needed in stroke patients.

Stable-isotope analysis of a deep-sea benthic-fish assemblage: evidence of an enriched benthic food web.

Science.gov (United States)

Boyle, M D; Ebert, D A; Cailliet, G M

2012-04-01

In this study, fishes and invertebrates collected from the continental slope (1000 m) of the eastern North Pacific Ocean were analysed using stable-isotope analysis (SIA). Resulting trophic positions (T(P) ) were compared to known diets and habitats from the literature. Dual isotope plots indicated that most species groups (invertebrates and fishes) sorted as expected along the carbon and nitrogen axes, with less intraspecific variability than interspecific variability. Results also indicated an isotopically distinct benthic and pelagic food web, as the benthic food web was more enriched in both nitrogen and carbon isotopes. Trophic positions from SIA supported this finding, resulting in the assignment of fishes to different trophic positions from those expected based on published dietary information. These differences can be explained largely by the habitat of the prey and the percentage of the diet that was scavenged. A mixing model estimated dietary contributions of prey similar to those of the known diet of Bathyraja trachura from stomach-content analysis (SCA). Linear regressions indicated that trophic positions calculated from SIA and SCA, when plotted against B. trachura total length for 32 individuals, exhibited similar variation and patterns. Only the T(P) from SCA yielded significant results (stomach content: P 0·05). © 2012 The Authors. Journal of Fish Biology © 2012 The Fisheries Society of the British Isles.

Pramana – Journal of Physics | Indian Academy of Sciences

Indian Academy of Sciences (India)

SIA) in a model representing Mo has been investigated using the modified analytical embedded atom method (MAEAM). The lattice relaxations are treated with the molecular dynamics (MD) simulation at absolute zero of temperature.

23 CFR 661.5 - What definitions apply to this regulation?

Science.gov (United States)

2010-04-01

... NBI. Structure Inventory and Appraisal (SI&A) Sheet means the graphic representation of the data recorded and stored for each NBI record in accordance with the Recording and Coding Guide for the Structure...

Tribunale di Santa Maria Capua Vetere - sezione lavoro Ord. 17 marzo 2013, dr Martorana S contro SSC s.r.l.

Directory of Open Access Journals (Sweden)

Calogero Massimo Cammalleri

2013-07-01

Full Text Available Lavoro (controversie – licenziamento intimato dopo ­l'entrata in vigore della legge n. 183 del 2010 - termine di 270 giorni per il deposito del ricorso – applicabilità – proroga del primo termine di impugnazione di 60 giorni di cui al d.l. n. 225 del 2010 – inapplicabi­lità* Lavoro (controversie – area della tutela obbligatoria - licenziamento intimato prima del­l'entrata in vigore della legge n. 92 del 2012 - giudizio in­staurato successivamen­te – nuovo rito - applicabilità.* Lavoro (rapporto – licenziamento intimato prima del­l'entrata in vigore della legge n. 92 del 2012 – giudizio in­staurato successivamente – art. 18 nuovo testo – applicabilità – esclusione.* Benché l'art. 2, co. 54 D.L. 29 dicembre 2010, n. 225 abbia differito al 31 dicembre 2011 l'efficacia della modifica del primo comma dell'art. 6 legge n. 604 del 1966 - relativa al termi­ni di decadenza di 60 giorni per la impugnazione con qualsiasi atto scritto, anche extragiudi­ziale, idoneo a rendere nota la volontà del lavoratore di impugnare il licenziamento stesso - in ragione dell'espressa limitazione dell'ambito di applicazione della proroga al solo predetto termine di sessanta giorni ed al solo primo comma dell'art. 6 legge n. 604 del 1966, sia invece, efficace la previsione del termine decadenziale dei 270 giorni per l'impugnativa giudiziale dei licenziamenti già assoggettati all'applicazione del termine decadenziale di 60 giorni. Alla controversia di impugnazione del licenziamento, il cui ricorso sia stato depositato suc­cessivamente all'entrata in vigore della legge n. 92 del 2012, si applica il nuovo rito speciale, ancorché il licenziamento sia sia perfezionato in data anteriore.* Alla controversia di impugnazione del licenziamento intimato prima dell'entrata in vigore della legge n. 92 del 2012, ancorchè regolata dal nuovo rito speciale, continua il testo dell'art. 18 della legge n. 300 del 1970 vigente alla data di intimazione

Illustrating the benefit of using hourly monitoring data on secondary inorganic aerosol and its precursors for model evaluation

Directory of Open Access Journals (Sweden)

M. Schaap

2011-11-01

Full Text Available Secondary inorganic aerosol, most notably ammonium nitrate and ammonium sulphate, is an important contributor to ambient particulate mass and provides a means for long range transport of acidifying components. The modelling of the formation and fate of these components is challenging. Especially, the formation of the semi-volatile ammonium nitrate is strongly dependent on ambient conditions and the precursor concentrations. For the first time an hourly artefact free data set from the MARGA instrument is available for the period of a full year (1 August 2007 to 1 August 2008 at Cabauw, the Netherlands. This data set is used to verify the results of the LOTOS-EUROS model. The comparison showed that the model underestimates the SIA levels. Closer inspection revealed that base line values appear well estimated for ammonium and sulphate and that the underestimation predominantly takes place at the peak concentrations. For nitrate the variability towards high concentrations is much better captured, however, a systematic relative underestimation was found. The model is able to reproduce many features of the intra-day variability observed for SIA. Although the model captures the seasonal and average diurnal variation of the SIA components, the modelled variability for the nitrate precursor gas nitric acid is much too large. It was found that the thermodynamic equilibrium module produces a too stable ammonium nitrate in winter and during night time in summer, whereas during the daytime in summer it is too unstable. We recommend to improve the model by verification of the equilibrium module, inclusion of coarse mode nitrate and to address the processes concerning SIA formation combined with a detailed analysis of the data set at hand. The benefit of the hourly data with both particulate and gas phase concentrations is illustrated and a continuation of these measurements may prove to be very useful in future model evaluation and improvement studies. Based

Chemical and toxicological characterization of exhaust emissions from alternative fuels for urban public transport; Caratterizzazione chimica e tossicologica delle emissioni da carburanti alternativi per il trasporto pubblico nelle aree urbane

Energy Technology Data Exchange (ETDEWEB)

Turrio Baldassarri, L; Conti, R; Crebelli, B; Iamicelli, A L [Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanita, Roma (Italy); De Berardis, M [Dipartimento di Tecnologie e Salute, Istituto Superiore di Sanita, Roma (Italy); Gambino, A L; Iannaccone, S [Istituto dei Motori, CNR, Napoli (Italy)

2008-07-01

The Istituto Superiore di Sanita (ISS, the National Institute of Health of Italy) and the Istituto dei Motori (IM) of the Consiglio Nazionale delle Ricerche (CNR, National Research Council) have carried out this study, jointly funded by the two institutes together with the Ministry of Environment. The chemical and toxicological characteristics of emissions from two urban bus engines were studied: a diesel engine fueled with both diesel oil and bio diesel blend and an equivalent spark-ignition one fuelled with compressed natural gas, operating in steady-state conditions. Regulated and unregulated pollutants, such as carcinogenic polycyclic aromatic hydrocarbons and nitrated derivatives, carbonyl compounds and light aromatic hydrocarbons were quantified. Mutagenicity of the emissions was evaluated by the Salmonella typhimurium/mammalian microsome assay. The effect of the fuels under study on the size distribution of particulate matter was also evaluated. The impact of diesel-powered transport on urban air quality, and the potential benefits for human health deriving from the use of natural gas for public transport, are discussed. [Italian] L'Istituto Superiore di Sanita (ISS) e l'Istituto dei Motori (IM) del Consiglio Nazionale delle Ricerche CNR) di Napoli hanno collaborato alla realizzazione di questo progetto, co-finanziato dai due istituti e dal Ministero dell'Ambiente. Sono state caratterizzate, da un punto di vista chimico e tossicologico, le emissioni di motori destinati al trasporto pubblico urbano, alimentati con gasolio, gas naturale e biodiesel. Sono stati quantificati sia gli inquinanti regolamentati sia quelli non regolamentati, con particolare interesse ai composti con rilevanza tossicologica, come gli idrocarburi policiclici aromatici, i loro derivati nitrati, i composti carbonilici e gli aromatici volatili. E stata quindi valutata la mutagenicita degli estratti, sia del particolato sia della fase vapore, tramite il test di reversione in Salmonella

Lo screening auxologico: un'indagine necessaria per la prevenzione dell'obesitá in etá scolare

Directory of Open Access Journals (Sweden)

R. La Licata

2003-05-01

Full Text Available

Obiettivi: l’interesse suscitato dall’obesità in età scolare è in continuo aumento, sia a causa della prevalenza sempre più estesa di tale patologia in questa età, sia perché il bambino vive con ansia e ostilità questo suo stato divenendo spesso oggetto di derisione da parte del gruppo. In un progetto di educazione alimentare che potesse avere un’azione di prevenzione primaria nei riguardi dell’obesità in età evolutiva; il nostro obiettivo è stato quello di effettuare uno screening prima di iniziare l’intervento su una porzione di popolazione scolastica per valutare lo stato auxologico dei soggetti e saggiare le loro conoscenze sulla nutrizione e sulle abitudini alimentari. Abbiamo ritenuto che ormai sia assolutamente necessario ricavare queste informazioni per poi programmare interventi efficaci ed efficienti per migliorare la qualità di ogni programma di educazione alimentare.

Materiali e metodi: l’indagine condotta in tre scuole elementari di Palermo ha coinvolto per ogni scuola due terze, due quarte, due quinte per un totale di 360 bambini con un’età compresa tra i 7 e gli 11 anni. Per la valutazione auxologica sono stati presi in considerazione statura, peso ed età cronologica secondo il metodo di J.M. Tanner. Il rilevamento delle abitudini alimentari e stili di vita è stato effettuato per mezzo di un questionario a risposta multipla.

Risultati: dai risultati di questa indagine preliminare è emerso che la prevalenza dell’obesità in età evolutiva nella nostra popolazione si avvicina notevolmente a quella italiana che è del 19%. Lo stile di vita sedentario aggrava la già precaria situazione dovuta alla cattiva alimentazione.

Conclusioni: dalle considerazioni fatte appare evidente quanto sia necessario e urgente un intervento efficiente di educazione alimentare che non resti sporadico e privo di una metodologia ben

Pneumonia Prevention during a Humanitarian Emergency: Cost-effectiveness of Haemophilus Influenzae Type B Conjugate Vaccine and Pneumococcal Conjugate Vaccine in Somalia.

Science.gov (United States)

Gargano, Lisa M; Hajjeh, Rana; Cookson, Susan T

2015-08-01

Pneumonia is a leading cause of death among children less than five years old during humanitarian emergencies. Haemophilus influenzae type b (Hib) and Streptococcus pneumoniae are the leading causes of bacterial pneumonia. Vaccines for both of these pathogens are available to prevent pneumonia. Problem This study describes an economic analysis from a publicly funded health care system perspective performed on a birth cohort in Somalia, a country that has experienced a protracted humanitarian emergency. An impact and cost-effectiveness analysis was performed comparing: no vaccine, Hib vaccine only, pneumococcal conjugate vaccine 10 (PCV10) only, and both together administered through supplemental immunization activities (SIAs). The main summary measure was the incremental cost per disability-adjusted life-years (DALYs) averted. One-way sensitivity analysis was conducted for uncertainty in parameter values. Each SIA would avert a substantial number of cases and deaths. Compared with no vaccine, the DALYs averted by two SIAs for two doses of Hib vaccine was US $202.93 (lower and upper limits: $121.80-$623.52), two doses of PCV10 was US $161.51 ($107.24-$227.21), and two doses of both vaccines was US $152.42 ($101.20-$214.42). Variables that influenced the cost-effectiveness for each strategy most substantially were vaccine effectiveness, case fatality rates (CFRs), and disease burden. The World Health Organization (WHO) defines a cost-effective intervention as costing one to three times the per capita gross domestic product (GDP; in 2011, for Somalia=US $112). Based on the presented model, Hib vaccine alone, PCV10 alone, or Hib vaccine and PCV10 given together in SIAs are cost-effective interventions in Somalia. The WHO/Strategic Advisory Group of Experts decision-making factors for vaccine deployment appear to have all been met: the disease burden is large, the vaccine-related risk is low, prevention in this setting is more feasible than treatment, the vaccine

Genetic diversity and DNA fingerprint study in tomato (Solanum ...

African Journals Online (AJOL)

User_Name

tomato (S. lycopersicon) that have different origin and grown under. Egyptian environment ..... Saccharomyces cerevisiae (Sia et al., 2000) up to 10-3 in the pipefish .... (2000). Analysis of microsatellite mutations in the mitochondrial DNA.

SIA „AUTO ATVARS” darbība Latvijas autotirgū.

OpenAIRE

Spila, Andis

2007-01-01

Pēdējo gadu laikā auto tirdzniecība ir viena no progresējošākajām nozarēm Latvijas tautsaimniecībā. Attīstoties jaunu automašīnu tirdzniecībai Latvijā attīstās arī citas vispārējai Latvijas attīstībai svarīgas nozares, tādas kā apdrošināšana, kreditēšana, būvniecība u.c. Pašreiz Latvijā piedāvājumā pārstāvētas praktiski visas pasaulē populārākās automašīnu markas, atsevišķas markas tirgo pat divas un vairāk kompānijas. Iespējams, jau pēc dažiem gadiem būs vēl vairāk jaunu auto ti...

Displacement cascades and defect annealing in tungsten, Part II: Object kinetic Monte Carlo simulation of tungsten cascade aging

Energy Technology Data Exchange (ETDEWEB)

Nandipati, Giridhar, E-mail: giridhar.nandipati@pnnl.gov [Pacific Northwest National Laboratory, Richland, WA (United States); Setyawan, Wahyu; Heinisch, Howard L. [Pacific Northwest National Laboratory, Richland, WA (United States); Roche, Kenneth J. [Pacific Northwest National Laboratory, Richland, WA (United States); Department of Physics, University of Washington, Seattle, WA 98195 (United States); Kurtz, Richard J. [Pacific Northwest National Laboratory, Richland, WA (United States); Wirth, Brian D. [University of Tennessee, Knoxville, TN (United States)

2015-07-15

The results of object kinetic Monte Carlo (OKMC) simulations of the annealing of primary cascade damage in bulk tungsten using a comprehensive database of cascades obtained from molecular dynamics (Setyawan et al.) are described as a function of primary knock-on atom (PKA) energy at temperatures of 300, 1025 and 2050 K. An increase in SIA clustering coupled with a decrease in vacancy clustering with increasing temperature, in addition to the disparate mobilities of SIAs versus vacancies, causes an interesting effect of temperature on cascade annealing. The annealing efficiency (the ratio of the number of defects after and before annealing) exhibits an inverse U-shape curve as a function of temperature. The capabilities of the newly developed OKMC code KSOME (kinetic simulations of microstructure evolution) used to carry out these simulations are described.

The effect of C concentration on radiation damage in Fe–Cr–C alloys

Energy Technology Data Exchange (ETDEWEB)

Meinander, A., E-mail: andrea.meinander@helsinki.fi [EURATOM-Tekes, Department of Physics, P.O. Box 43, FI-00014 University of Helsinki (Finland); Henriksson, K.O.E. [EURATOM-Tekes, Department of Physics, P.O. Box 43, FI-00014 University of Helsinki (Finland); Björkas, C. [EURATOM-Tekes, Department of Physics, P.O. Box 43, FI-00014 University of Helsinki (Finland); Institute of Energy and Climate Research – Plasma Physics, Forschungszentrum Jülich GmbH, Association EURATOM-FZJ, Partner in the Trilateral Euregio Cluster, Jülich (Germany); Vörtler, K.; Nordlund, K. [EURATOM-Tekes, Department of Physics, P.O. Box 43, FI-00014 University of Helsinki (Finland)

2013-11-15

Using a recently developed analytical bond-order potential for the complete ternary system, we performed molecular dynamics simulations of the primary radiation damage by displacement cascades in different Fe–Cr–C model alloys. We compared results obtained with this new potential to previous studies employing potentials for the binary Fe–Cr and Fe–C systems. We analysed the effect of C concentration on the number of Frenkel pairs produced by the cascades, as well as on clustering of vacancies and self-interstitial atoms (SIAs), and on the Cr and C content in the defects. The effect of C concentration on defect production was negligible, except at very high concentrations of over 1 at.% C. The main effect was in the Cr content of clustered SIAs, which increased with increasing C concentration.

Generalized threshold resummation for semi-inclusive e+e- annihilation

International Nuclear Information System (INIS)

Lo Presti, N.A.; Vogt, A.

2012-02-01

Recently methods have been developed to extend the resummation of large-x double logarithms in inclusive deep-inelastic scattering (DIS) to terms not addressed by the soft-gluon exponentiation. Here we briefly outline our approach based on fixed-order results, the general large-x structure in dimensional regularization and the all-order factorization of mass singularities, which is directly applicable also to semi-inclusive e + e - annihilation (SIA). We then present some main results for the corresponding timelike splitting functions and transverse and longitudinal fragmentation functions. The close relation between DIS and SIA facilitates the determination of additional third-order results for the latter function which is fully known only at the next-to-leading order. Therefore all above quantities can be resummed at next-to-next-to-leading logarithmic accuracy. (orig.)

Use of Semantic Wikis to support collaborative learning

Directory of Open Access Journals (Sweden)

Mauro Coccoli

2012-08-01

Full Text Available Semantic Wiki consentono, tramite un linguaggio comprensibile agli elaboratori e formalmente definito, l’annotazione semantica dei contenuti delle pagine Wiki e la rappresentazione esplicita delle relazioni di significato tra essi presenti. Essi offrono la possibilità di sfruttare sia i vantaggi delle tecnologie basate su ontologie sia i meccanismi collaborativi propri dei Wiki. L’articolo descrive un progetto, denominato Semantic WikiSUN, avviato per indagare le prospettive didattiche di tali sistemi. Esso è basato su un quadro teorico complesso che integra evidenze neurocognitive, teorie dell’apprendimento e modelli costruttivisti-sociali della conoscenza. Obiettivo del contributo è, sulla base della esperienza intrapresa, discutere potenzialità e criticità didattiche dei Semantic Wiki, estendendo talvolta la riflessione a considerazioni più generali sui processi di apprendimento mediati da tecnologie semantiche.

Displacement cascades and defect annealing in tungsten, Part II: Object kinetic Monte Carlo Simulation of Tungsten Cascade Aging

Energy Technology Data Exchange (ETDEWEB)

Nandipati, Giridhar; Setyawan, Wahyu; Heinisch, Howard L.; Roche, Kenneth J.; Kurtz, Richard J.; Wirth, Brian D.

2015-07-01

The results of object kinetic Monte Carlo (OKMC) simulations of the annealing of primary cascade damage in bulk tungsten using a comprehensive database of cascades obtained from molecular dynamics (Setyawan et al.) are described as a function of primary knock-on atom (PKA) energy at temperatures of 300, 1025 and 2050 K. An increase in SIA clustering coupled with a decrease in vacancy clustering with increasing temperature, in addition to the disparate mobilities of SIAs versus vacancies, causes an interesting effect of temperature on cascade annealing. The annealing efficiency (the ratio of the number of defects after and before annealing) exhibits an inverse U-shape curve as a function of temperature. The capabilities of the newly developed OKMC code KSOME (kinetic simulations of microstructure evolution) used to carry out these simulations are described.

Uzņēmuma McDonalds konkurētspējas novērtēšanas un tās uzlabošanas iespējas

OpenAIRE

Artemjeva, Anžela

2012-01-01

Bakalaura darba tēma – „Uzņēmuma McDonalds konkurētspējas novērtēšana un tās uzlabošanas iespējas”. Bakalaura darba mērķis-pamatojoties uz teorētiskām atziņām par konkurenci un konkurētspēju, izpētīt SIA McDonalds konkurētspēju tirgū un tās pilnveidošanas iespējas balstoties uz Latvijas, Lietuvas un Igaunijas investīciju nozares analīzes datu rezultātiem, izdarīt secinājumus un sniegt priekšlikumus SIA McDonalds konkurētspējas uzlabošanai. Bakalaura darba izstrādes gaitā autore ir izstr...

Síndrome de insuficiência androgênica: critérios diagnósticos e terapêuticos Androgen insufficiency syndrome: diagnostic and therapeutic criteria

Directory of Open Access Journals (Sweden)

César Eduardo Fernandes

2006-01-01

Full Text Available A síndrome da insuficiência androgênica na mulher (SIA desperta, mesmo nos dias atuais, muitas discussões e encerra muitas controvérsias. Sabe-se, no entanto, que os níveis plasmáticos de testosterona declinam progressivamente ao longo do período reprodutivo. Conceitua-se a SIA como o conjunto de sintomas clínicos, a presença de biodisponibilidade diminuída de testosterona e os níveis normais de estrogênios. Entre os principais sintomas, citam-se o comprometimento do bem-estar, o humor disfórico, a fadiga sem causa aparente, o comprometimento do desejo sexual, o emagrecimento e a instabilidade vasomotora em mulheres pós-menopáusicas sob terapêutica estrogênica. Esses sintomas, no entanto, são potencialmente atribuíveis a diferentes etiologias e dificultam o correto diagnóstico na maioria dos casos, ainda que ele seja lembrado com freqüência em pacientes que se submetem à ooforectomia bilateral. O diagnóstico da SIA parece ser essencialmente clínico, não havendo a necessidade das dosagens laboratoriais para a sua comprovação. Não se deve indicar a terapêutica androgênica (TA em pacientes que não estejam adequadamente estrogenizadas. Considera-se a testosterona o hormônio ideal para a TA. As pacientes com sintomas sugestivos de SIA, excluídas outras causas identificáveis, especialmente se pós-menopáusicas, são candidatas à TA. Não existem dados de segurança sobre a TA em usuárias em longo prazo. A via transdérmica - através de adesivos, cremes e gel - parece ser preferível à oral.The women’s androgen insufficiency syndrome (AIS arises, even nowadays, many debates and clears a lot of controversies. It is known, however, that the plasmatic levels of testosterone gradually decline through the reproductive period. AIS is appraised as a set of clinical symptoms, bioavailability presence diminished of testosterone and normal levels of estrogen. Among the main symptoms that remind the diagnosis are the

Computational Study of Chalcopyrite Semiconductors and Their Non-Linear Optical Properties

National Research Council Canada - National Science Library

Lambrecht, Walter R

2007-01-01

... (Including cation antisites, cation and anion vacancies) and CdGeAs2; a study of the feasibility of nonciritical phase matching and associated nonlinear optical parameters in CdSiP2 and CdSIAs2...

Functional connectivity of coral reef fishes in a tropical seascape assessed by compound-specific stable isotope analyses

KAUST Repository

McMahon, Kelton W.

2011-01-01

. The compound-specific SIA approach presented in this thesis will be particularly valuable for tracking the movement of species and life-stages not amenable to conventional tagging techniques. This thesis provides quantitative scientific support for establishing

Experiences from polio supplementary immunization activities in ...

African Journals Online (AJOL)

2014-05-31

May 31, 2014 ... lessons from supplementary immunization activities (SIAs) conducted in the State that will be useful to ... Poliovirus invades the central nervous system and causes ..... The vaccine wastage rate of 6.6% was slightly higher.

Evolution of an alumina-magnesia/self-forming spinel castable. Part I: Microstructural features Evolução de um refratário de espinélio auto-formado de alumina-magnésia. Parte I: Aspectos microestruturais

Directory of Open Access Journals (Sweden)

D. Gutiérrez-Campos

1999-06-01

Full Text Available Refractories containing magnesium aluminate spinel (MgAl2O4 are materials for emerging technology in several applications like cement and steelmaking processes. In order to deep the understanding of these castables, this work presents the microstructural characteristics of an alumina-magnesia/self-forming spinel castable. Several variables such as MgO content, firing temperature and spinel formation are analyzed through XRD and SEM analysis. The results showed that the processes of spinel formation and nucleation are not strongly affected by the MgO content, but that the crystal growth is enhanced for samples with 6.0 wt% MgO. Hibonite (CA6 bonding in the castable matrix showed a needlelike structure that could increase hot properties of the material. MgO content in the castable seems to affect the hibonite development. The development of a self-forming spinel castable without any synthetic spinel grains appears to be promissory for optimum refractory linings.Refratários contendo espinélio de aluminato de magnésio (MgAl2O4 são materiais para tecnologia emergentes em várias aplicações tais como cimento e processos siderúrgicos. Com a finalidade de melhorar o entendimento destes refratários, este trabalho apresenta as características microestruturais de um refratário espinélio auto-formado de alumina-magnésia. Várias variáveis tais como teor de MgO, temperatura de queima e formação de espinélio são analisadas por meio de difração de raios X e microscopia eletrônica de varredura. Os resultados mostram que os processos de formação de espinélio e de nucleação não são fortemente influenciados pelo teor de MgO, mas que o crescimento de cristal é aumentado para amostras com 6.0% em peso de MgO. A ligação hibonita (CA6 na matriz do refratário mostrou uma estrutura tipo agulha que poderia melhorar as propriedades a quente do material. O teor de MgO no refratário parece influenciar o desenvolvimento da hibonita. O

Draama 2007. Töörahu / Ene Paaver

Index Scriptorium Estoniae

Paaver, Ene, 1963-

2008-01-01

Ülevaade 2007. aasta eesti draamast. Pikemalt käsitletakse järgmisi autoreid ja nende näidendeid: Mart Kivastik "Tõnu võitlused", Mart Kivastik "Eesti asi", Mart Kivastik "Sõdur", Mart Kivastik "Kuninga viimane lahing ja ülikooli algus", Mart Kivastik, "Nokia 3310", Andrus Kivirähk "Voldemar", Andrus Kivirähk "Uljas neitsi", Hendrik Toompere "Kommunisti surm", Andres Ehin "Saatuslik kihlvedu ehk Volquin Varbola all", Jan Rahman "Jõujaam", Jaak Kõdar "Muinassaar", Karl Berg "Teekond valguse riiki", Angela Randmets "Lembelood vanas linnas", Toomas Kall "Tähtede sadu", Lauri Vahtre "Muna EÜE", Urmas Espenberg "Kestvad kiiduavaldused", Kalju Saaber "Koduvõõrad", Indrek Hirv "Pauluse kiriku kellad", Katrin Saukas "Võlg", Heidi Sarapuu "Austatud Riigikogu liikmed!", Heidi Sarapuu "Helisev viis", Heidi Sarapuu "Ankur hiivata", Jakob Karu "Vanaema juures", Jim Ashilevi "Nagu poisid vihma käes", Jim Ashilevi "Portselansuits", Eva Koff "Mirr", Jaak Prints "Karaoke", Kati Murutar "Mina, naine!", Ott Aardam "Börs ja Börsitar", Andrus Kivirähk, Jan Rahman, Contra "Kõrts", Mart Kase "Perekond", Villu Tamme "Haned võlgu"; Tiit Ojasoo ja Ene-Liis Semperi "GEP ehk Gorjatshije estonskije parni"

Hypothesis: the regulation of the partial pressure of oxygen by the serotonergic nervous system in hypoxia.

Science.gov (United States)

Devereux, Diana; Ikomi-Kumm, Julie

2013-03-01

The regulation of the partial pressure of oxygen by the serotonergic nervous system in hypoxia is a hypothesis, which proposes an inherent operative system in homo sapiens that allows central nervous system and endocrine-mediated vascular system adaption to variables in partial pressure of oxygen, pH and body composition, while maintaining sufficient oxygen saturation for the immune system and ensuring protection of major organs in hypoxic and suboptimal conditions. While acknowledging the importance of the Henderson-Hasselbalch equation in the regulation of acid base balance, the hypothesis seeks to define the specific neuroendocrine/vascular mechanisms at work in regulating acid base balance in hypoxia and infection. The SIA (serotonin-immune-adrenergic) system is proposed as a working model, which allows central nervous system and endocrine-mediated macro- and micro vascular 'fine tuning'. The neurotransmitter serotonin serves as a 'hypoxic sensor' in concert with other operators to orchestrate homeostatic balance in normal and pathological states. The SIA system finely regulates oxygen, fuel and metabolic buffering systems at local sites to ensure optimum conditions for the immune response. The SIA system is fragile and its operation may be affected by infection, stress, diet, environmental toxins and lack of exercise. The hypothesis provides new insight in the area of neuro-gastroenterology, and emphasizes the importance of diet and nutrition as a complement in the treatment of infection, as well as the normalization of intestinal flora following antibiotic therapy. Copyright © 2012 Elsevier Ltd. All rights reserved.

Changes in serum growth factors in stroke rehabilitation patients and their relation to hemiparesis improvement.

Science.gov (United States)

Okazaki, Hideto; Beppu, Hidehiko; Mizutani, Kenmei; Okamoto, Sayaka; Sonoda, Shigeru

2014-07-01

Predicting recovery from hemiparesis after stroke is important for rehabilitation. A few recent studies reported that the levels of some growth factors shortly after stroke were positively correlated with the clinical outcomes during the chronic phase. The aim of this study was to examine the relationships between the serum levels of growth factors (vascular endothelial growth factor [VEGF], insulin-like growth factor-I [IGF-I], and hepatocyte growth factor [HGF]) and improvement in hemiparesis in stroke patients who received rehabilitation in a postacute rehabilitation hospital. Subjects were 32 stroke patients (cerebral infarction: 21 and intracerebral hemorrhage [ICH]: 11). We measured serum levels of VEGF, IGF-I, and HGF and 5 items of the Stroke Impairment Assessment Set (SIAS) for hemiparesis on admission and at discharge. Age-matched healthy subjects (n=15) served as controls. Serum levels of VEGF and HGF in cerebral infarct patients on admission were higher than those in control subjects, and the serum levels of IGF-I in stroke patients were lower than those in controls. The level of HGF in ICH patients on admission was negatively correlated with gains in SIAS, and higher outliers in HGF concentration were correlated with lower gains in SIAS. Focusing on the extremely high levels of these factors may be a predictor of the low recovery from hemiparesis after stroke. Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.

Poliomyelitis eradication in China: 1953-2012.

Science.gov (United States)

Yu, Wen-Zhou; Wen, Ning; Zhang, Yong; Wang, Hai-Bo; Fan, Chun-Xiang; Zhu, Shuang-Li; Xu, Wen-Bo; Liang, Xiao-Feng; Luo, Hui-Ming; Li, Li

2014-11-01

Poliomyelitis has historically been endemic in China and has been considered an important cause of disability and death. We reviewed strategies and measures of poliomyelitis control and eradication from 1953 to 2012. Data from notifiable disease and routine immunization reporting systems and acute flaccid paralysis (AFP) surveillance were analyzed. About 20 000 poliomyelitis cases were reported annually in the prevaccine era. During 1965-1977, live, attenuated oral poliomyelitis vaccine (OPV) was administered to children through annual mass campaigns in the winter, and the number of poliomyelitis cases started to decline. A cold chain system was established during 1982, and OPV coverage increased during the early stage of the Expanded Programme on Immunization, from 1978 to 1988. Between 1989 and 1999, routine immunization was strengthened, supplementary immunization activities (SIAs) were conducted, and the AFP surveillance system was established. China reported a last indigenous poliomyelitis case in 1994 and was certified as free of polio in 2000. To maintain its polio-free status, China kept >90% coverage of 3 doses of OPV, conducted SIAs in high-risk areas, and maintained high-quality of AFP surveillance. China succeeded in stopping the outbreak in Xinjiang in 2011. China's polio-free status was achieved and maintained through strengthening routine immunization and implementing SIAs and AFP surveillance. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

L’AZIONE DI CANCELLAZIONE - TUTELA DEI DIRITTI TAVOLARI

Directory of Open Access Journals (Sweden)

Zrinka Radić

2017-01-01

Full Text Available Il titolare di un diritto tavolare, leso dall’iscrizione a favore di altro soggetto, al fi ne di tutelare il proprio diritto è autorizzato a pretendere la cancellazione di qualsiasi iscrizione che lo offenda ed a ripristinare nel libro fondiario lo stato precedente. Se l’iscrizione di un diritto tavolare a favore di altro soggetto sia o no fondata, verrà stabilito dal tribunale in sede contenziosa. L’autore del lavoro si occupa della questione della legittimazione attiva e passiva e dei termini quali presupposti incontrovertibili volti alla presentazione della domanda di cancellazione. Si disaminano le questioni che sono problematiche in giurisprudenza ed in dottrina. Precisamente: la valutazione della legittimazione attiva, le questioni riguardanti dunque l’individuazione di coloro che in qualità di «lesi nel proprio diritto tavolare» possano intraprendere l’azione di cancellazione e la questione circa i tipi di iscrizione in occasione delle quali si possa giungere ad una tale lesione. Ancora, si valuta se l’attore debba in caso di azione di cancellazione provare il suo diritto sostanziale e quali eccezioni possa sollevare nell’azione. Al centro dell’attenzione v’è anche la questione della legittimazione passiva e dei termini quali presupposti incontrovertibili ai fi ni della presentazione della domanda di cancellazione; come pure l’interrogativo se l’azione di cancellazione sia giustifi cata soltanto nel caso di un’iniziale nullità del titolo o se sia suffi ciente anche una nullità successiva.

Diet of bottlenose dolphins (Tursiops truncatus from the Gulf of Cadiz: Insights from stomach content and stable isotope analyses.

Directory of Open Access Journals (Sweden)

Joan Giménez

Full Text Available The ecological role of species can vary among populations depending on local and regional differences in diet. This is particularly true for top predators such as the bottlenose dolphin (Tursiops truncatus, which exhibits a highly varied diet throughout its distribution range. Local dietary assessments are therefore critical to fully understand the role of this species within marine ecosystems, as well as its interaction with important ecosystem services such as fisheries. Here, we combined stomach content analyses (SCA and stable isotope analyses (SIA to describe bottlenose dolphins diet in the Gulf of Cadiz (North Atlantic Ocean. Prey items identified using SCA included European conger (Conger conger and European hake (Merluccius merluccius as the most important ingested prey. However, mass-balance isotopic mixing model (MixSIAR, using δ13C and δ15N, indicated that the assimilated diet consisted mainly on Sparidae species (e.g. seabream, Diplodus annularis and D. bellottii, rubberlip grunt, Plectorhinchus mediterraneus, and common pandora, Pagellus erythrinus and a mixture of other species including European hake, mackerels (Scomber colias, S. japonicus and S. scombrus, European conger, red bandfish (Cepola macrophthalma and European pilchard (Sardina pilchardus. These contrasting results highlight differences in the temporal and taxonomic resolution of each approach, but also point to potential differences between ingested (SCA and assimilated (SIA diets. Both approaches provide different insights, e.g. determination of consumed fish biomass for the management of fish stocks (SCA or identification of important assimilated prey species to the consumer (SIA.

The effects of the Odense Overweight Intervention Study

DEFF Research Database (Denmark)

Larsen, Kristian Traberg; Huang, Tao; Ried-Larsen, Mathias

of the DCIA in BMI z-score, clustered risk z-score, systolic blood pressure, abdominal fat-%, waist circumference, cardiorespiratory fitness, and total cholesterol/HDL ratio. In body fat-%, waist circumference and triglycerides, there is only a significant group difference at 6 weeks and not at 52 weeks......Aim: The primary aim of the study is to evaluate the effect of the Odense Overweight Intervention Study on BMI development. Methods: The OOIS is a semi-blinded randomized controlled trial with three measurement occasions. Participants were allocated into two intervention arms; a day camp...... intervention arm (DCIA) and a standard intervention arm (SIA). For the DCIA the camp lasted for six weeks and consisted of fun-based physical activities, healthy eating, and health classes. The following 10 months a family based intervention was accomplished. The SIA was offered a weekly activity session...

Geothermal heat can cool, too

International Nuclear Information System (INIS)

Wellstein, J.

2008-01-01

This article takes a look at how geothermal energy can not only be used to supply heating energy, but also be used to provide cooling too. The article reports on a conference on heating and cooling with geothermal energy that was held in Duebendorf, Switzerland, in March 2008. The influence of climate change on needs for heating and cooling and the need for additional knowledge and data on deeper rock layers is noted. The seasonal use of geothermal systems to provide heating in winter and cooling in summer is discussed. The planning of geothermal probe fields and their simulation is addressed. As an example, the geothermal installations under the recently renewed and extended 'Dolder Grand' luxury hotel in Zurich are quoted. The new SIA 384/6 norm on geothermal probes issued by the Swiss Association of Architects SIA is briefly reviewed.

Georges de Selve, Arnauld Chandon e Simon Bourgouyn: i primi traduttori cinquecenteschi delle Vite parallele di Plutarco.

Directory of Open Access Journals (Sweden)

Filippo Fassina

2017-12-01

Full Text Available Nei primi anni del Cinquecento, la Francia vede la riscoperta del genere letterario della biografia antica, il cui modello più illustre è Plutarco. Delle sue Vite parallele circolano numerose traduzioni francesi, che precedono di diversi anni la grande opera di Jacques Amyot del 1559. Oltre ad alcuni volgarizzamenti anonimi conservati manoscritti, possediamo anche un corpus di testi attribuiti con sicurezza a tre eruditi francesi, che nella prima metà del Cinquecento, hanno tradotto alcune vite plutarchee: si tratta di Georges de Selve, Arnauld Chandon e Simon Bourgouyn. Questi testi sono qui analizzati sia sotto l’aspetto letterario, sia sotto l’aspetto codicologico, al fine di ricostruirne la storia della tradizione manoscritta e, parallelamente, cercare di comprendere gli eventuali legami con la traduzione di Amyot, di cui questi primi esperimenti potrebbero rappresentare un modello.

«Più saggia di Edipo». Su alcune fonti di «Ödipus und die Sphinx» di Hofmannsthal

Directory of Open Access Journals (Sweden)

Elena Raponi

2016-12-01

Full Text Available Il saggio analizza la tragedia Ödipus und die Sphinx (Edipo e la Sfinge, 1906 di Hugo von Hofmannsthal in relazione con le sue fonti, mostrando come la figura di Eleonora Duse, tanto venerata dal poeta austriaco da indurlo a plasmare su di lei il ruolo di Giocasta, abbia provocato sia l’allontanamento dell’opera dalla primitiva fonte francese OEdipe et le Sphinx di Joséphin Péladan (1903, sia il suo avvicinamento al mondo poetico dannunziano, di cui l’attrice italiana era stata ispiratrice e interprete. Allo stesso tempo il saggio mostra come Hofmannsthal affidi alla dialettica interna ai personaggi della sua tragedia e in particolare a Giocasta il compito di ridimensionare e correggere il superomismo dannunziano, lasciando emergere, qui appena accennato, il mondo di delicate relazioni che caratterizzerà le commedie della maturità.

Ingegneria degli acquiferi

CERN Document Server

Molfetta, Antonio

2012-01-01

Il testo fornisce le conoscenze necessarie per affrontare, con un approccio quantitativo, i molteplici aspetti connessi al flusso delle risorse idriche sotterranee (acque di falda) e alla propagazione e bonifica di contaminanti nei sistemi acquiferi. Vengono illustrate le proprietà fondamentali che definiscono la capacità di immagazzinamento, trasporto e rilascio dell’acqua negli acquiferi, e successivamente, descritte le metodiche per la determinazione di tali parametri tramite l’esecuzione e l’interpretazione di prove di falda, di pozzo e di laboratorio. A partire dalla classificazione chimico fisica-tossicologica dei contaminanti vengono, quindi, analizzati i meccanismi di propagazione e illustrate le soluzioni analitiche dell’equazione del trasporto di massa nei mezzi porosi. L’ultima parte del testo è dedicata alla caratterizzazione e bonifica degli acquiferi contaminati. Il testo è rivolto sia agli studenti universitari, sia ai professionisti che debbano affrontare con un approccio quantit...

Amministrare lo studio dell'italiano: l'Ufficio Scolastico del Consolato Generale d'Italia a San Paolo

Directory of Open Access Journals (Sweden)

Alessandro Dell'Aira

2006-08-01

Full Text Available Questo articolo riprende in parte una questione generale già affrontata sulla rivista, e cioè il buon uso delle tecnologie dell'informazione e della comunicazione in ambito culturale e didattico. La questione riguarda soprattutto gli stili di insegnamento/apprendimento, di formazione e di amministrazione. Ci si sofferma sullo stile di gestione di un ufficio pubblico in una situazione amministrativa atipica, esercitata su un territorio vastissimo a favore di un'utenza dislocata sul territorio in modo non omogeneo. La conclusione è che l'uso agile e sistematico della rete globale e delle tecnologie informatiche e telematiche può aiutare gli Uffici scolastici italiani all'estero a gestire in contesti complessi i principali problemi connessi con la distanza dall'Italia, sia per l'insegnamento della lingua italiana nei corsi, sia per la formazione iniziale e continua dei docenti.

*Department of Biology,

African Journals Online (AJOL)

USER

2014-12-04

Dec 4, 2014 ... A Socioeconomic Impact Assessment (SIA) of Integrated Industrial ... food insecurity, lack of access to land for ... Pant Nagar in particular) is fast emerging .... Villages found in the southern side of the project site (100%) said ...

Current Launch Vehicle Practice and Data Base Assessment. Volume 1. Executive Summary and Report Body

Science.gov (United States)

1989-06-01

4 4 2 .2 .4 B a y e sia n .............................................................................................. 4...basic assumption for the method of estimating system relaibility in the present study is that the failure of the launch vehicle must occur in one of its

Психологические особенности банковской рекламы как формы коммуникационного поведения

OpenAIRE

Ибрагимова, Р.

2013-01-01

This article is devoted to the specifi cs of banking advertising in Rus- sia. Also analyzed the types of banking advertising and techniques that are used in this form of advertising. In addition, there are samples of advertising banks of Russia