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Sample records for showed strong enrichment

  1. Identification of a set of genes showing regionally enriched expression in the mouse brain

    Directory of Open Access Journals (Sweden)

    Marra Marco A

    2008-07-01

    Full Text Available Abstract Background The Pleiades Promoter Project aims to improve gene therapy by designing human mini-promoters ( Results We have utilized LongSAGE to identify regionally enriched transcripts in the adult mouse brain. As supplemental strategies, we also performed a meta-analysis of published literature and inspected the Allen Brain Atlas in situ hybridization data. From a set of approximately 30,000 mouse genes, 237 were identified as showing specific or enriched expression in 30 target regions of the mouse brain. GO term over-representation among these genes revealed co-involvement in various aspects of central nervous system development and physiology. Conclusion Using a multi-faceted expression validation approach, we have identified mouse genes whose human orthologs are good candidates for design of mini-promoters. These mouse genes represent molecular markers in several discrete brain regions/cell-types, which could potentially provide a mechanistic explanation of unique functions performed by each region. This set of markers may also serve as a resource for further studies of gene regulatory elements influencing brain expression.

  2. INSIGHTS INTO PRE-ENRICHMENT OF STAR CLUSTERS AND SELF-ENRICHMENT OF DWARF GALAXIES FROM THEIR INTRINSIC METALLICITY DISPERSIONS

    International Nuclear Information System (INIS)

    Leaman, Ryan

    2012-01-01

    Star clusters are known to have smaller intrinsic metallicity spreads than dwarf galaxies due to their shorter star formation timescales. Here we use individual spectroscopic [Fe/H] measurements of stars in 19 Local Group dwarf galaxies, 13 Galactic open clusters, and 49 globular clusters to show that star cluster and dwarf galaxy linear metallicity distributions are binomial in form, with all objects showing strong correlations between their mean linear metallicity Z-bar and intrinsic spread in metallicity σ(Z) 2 . A plot of σ(Z) 2 versus Z-bar shows that the correlated relationships are offset for the dwarf galaxies from the star clusters. The common binomial nature of these linear metallicity distributions can be explained with a simple inhomogeneous chemical evolution model, where the star cluster and dwarf galaxy behavior in the σ(Z) 2 - Z-bar diagram is reproduced in terms of the number of enrichment events, covering fraction, and intrinsic size of the enriched regions. The inhomogeneity of the self-enrichment sets the slope for the observed dwarf galaxy σ(Z) 2 - Z-bar correlation. The offset of the star cluster sequence from that of the dwarf galaxies is due to pre-enrichment, and the slope of the star cluster sequence represents the remnant signature of the self-enriched history of their host galaxies. The offset can be used to separate star clusters from dwarf galaxies without a priori knowledge of their luminosity or dynamical mass. The application of the inhomogeneous model to the σ(Z) 2 - Z-bar relationship provides a numerical formalism to connect the self-enrichment and pre-enrichment between star clusters and dwarf galaxies using physically motivated chemical enrichment parameters. Therefore we suggest that the σ(Z) 2 - Z-bar relationship can provide insight into what drives the efficiency of star formation and chemical evolution in galaxies, and is an important prediction for galaxy simulation models to reproduce.

  3. Uranium enrichment

    International Nuclear Information System (INIS)

    1989-01-01

    GAO was asked to address several questions concerning a number of proposed uranium enrichment bills introduced during the 100th Congress. The bill would have restructured the Department of Energy's uranium enrichment program as a government corporation to allow it to compete more effectively in the domestic and international markets. Some of GAO's findings discussed are: uranium market experts believe and existing market models show that the proposed DOE purchase of a $750 million of uranium from domestic producers may not significantly increase production because of large producer-held inventories; excess uranium enrichment production capacity exists throughout the world; therefore, foreign producers are expected to compete heavily in the United States throughout the 1990s as utilities' contracts with DOE expire; and according to a 1988 agreement between DOE's Offices of Nuclear Energy and Defense Programs, enrichment decommissioning costs, estimated to total $3.6 billion for planning purposes, will be shared by the commercial enrichment program and the government

  4. Inverse-Frontal Chromatography studies on enrichment of Boron-10 using quaternery 4-vinylpyridine-divinylbenzene resin

    International Nuclear Information System (INIS)

    Bejawada, Venki; Mohapatra, C.; Rao, A.S.; Prasad, K.L.; Murthy, P.K.; Rao, A.K.; Singh, H.P.; Vithal, G.K.; Kumar, Sangita D.

    2014-01-01

    In order to enrich 10 B, band migration of boric acid-mannitol with hydrochloric acid solution was performed by inverse frontal chromatography on a porous, 25% crosslinked, 38% quaternized 4-vinylpyridine-divinylbenzene resin (py-resin). The work was initiated to replace the existing strong base anion exchange resin type-II (SBA-II) which is used in Boron Enrichment Plant (BEP) of heavy water plant Manuguru. Before its application in BEP, it is mandatory to evaluate py-resin for its performance. The studies showed that maximum of 40% 10 B enrichment observed after 13 m band movement and there was no further improvement, hence profile sampling carried out after 28 m. (author)

  5. THE SUPERNOVA TRIGGERED FORMATION AND ENRICHMENT OF OUR SOLAR SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Gritschneder, M.; Lin, D. N. C. [Kavli Institute for Astronomy and Astrophysics, Peking University, Yi He Yuan Lu 5, Hai Dian, 100871 Beijing (China); Murray, S. D. [Lawrence Livermore National Laboratory, University of California, Livermore, CA 94550 (United States); Yin, Q.-Z. [Department of Geology, University of California, Davis, CA 95616 (United States); Gong, M.-N., E-mail: gritschneder@pku.edu.cn [Department of Physics, Tsinghua University, Hai Dian, 100084 Beijing (China)

    2012-01-20

    We investigate the enrichment of the pre-solar cloud core with short-lived radionuclides, especially {sup 26}Al. The homogeneity and the surprisingly small spread in the ratio {sup 26}Al/{sup 27}Al observed in the overwhelming majority of calcium-aluminium-rich inclusions in a vast variety of primitive chondritic meteorites places strong constraints on the formation of the solar system. Freshly synthesized radioactive {sup 26}Al has to be included and well mixed within 20 kyr. After discussing various scenarios including X-winds, asymptotic giant branch stars, and Wolf-Rayet stars, we come to the conclusion that triggering the collapse of a cold cloud core by a nearby supernova (SN) is the most promising scenario. We then narrow down the vast parameter space by considering the pre-explosion survivability of such a clump as well as the cross-section necessary for sufficient enrichment. We employ numerical simulations to address the mixing of the radioactively enriched SN gas with the pre-existing gas and the forced collapse within 20 kyr. We show that a cold clump of 10 M{sub Sun} at a distance of 5 pc can be sufficiently enriched in {sup 26}Al and triggered into collapse fast enough-within 18 kyr after encountering the SN shock-for a range of different metallicities and progenitor masses, even if the enriched material is assumed to be distributed homogeneously in the entire SN bubble. In summary, we envision an environment for the birthplace of the solar system 4.567 Gyr ago similar to the situation of the pillars in M16 nowadays, where molecular cloud cores adjacent to an H II region will be hit by an SN explosion in the future. We show that the triggered collapse and formation of the solar system as well as the required enrichment with radioactive {sup 26}Al are possible in this scenario.

  6. Global pressures, specific responses: effects of nutrient enrichment in streams from different biomes

    International Nuclear Information System (INIS)

    Artigas, Joan; García-Berthou, Emili; Gómez, Nora; Romaní, Anna M; Sabater, Sergi; Bauer, Delia E; Cochero, Joaquín; Cortelezzi, Agustina; Rodrigues-Capítulo, Alberto; Castro, Maria I; Donato, John C; Colautti, Darío C; Elosegi, Arturo; Feijoó, Claudia; Giorgi, Adonis; Leggieri, Leonardo; Muñoz, Isabel

    2013-01-01

    We assessed the effects of nutrient enrichment on three stream ecosystems running through distinct biomes (Mediterranean, Pampean and Andean). We increased the concentrations of N and P in the stream water 1.6–4-fold following a before–after control–impact paired series (BACIPS) design in each stream, and evaluated changes in the biomass of bacteria, primary producers, invertebrates and fish in the enriched (E) versus control (C) reaches after nutrient addition through a predictive-BACIPS approach. The treatment produced variable biomass responses (2–77% of explained variance) among biological communities and streams. The greatest biomass response was observed for algae in the Andean stream (77% of the variance), although fish also showed important biomass responses (about 9–48%). The strongest biomass response to enrichment (77% in all biological compartments) was found in the Andean stream. The magnitude and seasonality of biomass responses to enrichment were highly site specific, often depending on the basal nutrient concentration and on windows of ecological opportunity (periods when environmental constraints other than nutrients do not limit biomass growth). The Pampean stream, with high basal nutrient concentrations, showed a weak response to enrichment (except for invertebrates), whereas the greater responses of Andean stream communities were presumably favored by wider windows of ecological opportunity in comparison to those from the Mediterranean stream. Despite variation among sites, enrichment globally stimulated the algal-based food webs (algae and invertebrate grazers) but not the detritus-based food webs (bacteria and invertebrate shredders). This study shows that nutrient enrichment tends to globally enhance the biomass of stream biological assemblages, but that its magnitude and extent within the food web are complex and are strongly determined by environmental factors and ecosystem structure. (letter)

  7. Phylogeny is a powerful tool for predicting plant biomass responses to nitrogen enrichment.

    Science.gov (United States)

    Wooliver, Rachel C; Marion, Zachary H; Peterson, Christopher R; Potts, Brad M; Senior, John K; Bailey, Joseph K; Schweitzer, Jennifer A

    2017-08-01

    Increasing rates of anthropogenic nitrogen (N) enrichment to soils often lead to the dominance of nitrophilic plant species and reduce plant diversity in natural ecosystems. Yet, we lack a framework to predict which species will be winners or losers in soil N enrichment scenarios, a framework that current literature suggests should integrate plant phylogeny, functional tradeoffs, and nutrient co-limitation. Using a controlled fertilization experiment, we quantified biomass responses to N enrichment for 23 forest tree species within the genus Eucalyptus that are native to Tasmania, Australia. Based on previous work with these species' responses to global change factors and theory on the evolution of plant resource-use strategies, we hypothesized that (1) growth responses to N enrichment are phylogenetically structured, (2) species with more resource-acquisitive functional traits have greater growth responses to N enrichment, and (3) phosphorus (P) limits growth responses to N enrichment differentially across species, wherein P enrichment increases growth responses to N enrichment more in some species than others. We built a hierarchical Bayesian model estimating effects of functional traits (specific leaf area, specific stem density, and specific root length) and P fertilization on species' biomass responses to N, which we then compared between lineages to determine whether phylogeny explains variation in responses to N. In concordance with literature on N limitation, a majority of species responded strongly and positively to N enrichment. Mean responses ranged three-fold, from 6.21 (E. pulchella) to 16.87 (E. delegatensis) percent increases in biomass per g N·m -2 ·yr -1 added. We identified a strong difference in responses to N between two phylogenetic lineages in the Eucalyptus subgenus Symphyomyrtus, suggesting that shared ancestry explains variation in N limitation. However, our model indicated that after controlling for phylogenetic non

  8. Evaluating biomarkers for prognostic enrichment of clinical trials.

    Science.gov (United States)

    Kerr, Kathleen F; Roth, Jeremy; Zhu, Kehao; Thiessen-Philbrook, Heather; Meisner, Allison; Wilson, Francis Perry; Coca, Steven; Parikh, Chirag R

    2017-12-01

    A potential use of biomarkers is to assist in prognostic enrichment of clinical trials, where only patients at relatively higher risk for an outcome of interest are eligible for the trial. We investigated methods for evaluating biomarkers for prognostic enrichment. We identified five key considerations when considering a biomarker and a screening threshold for prognostic enrichment: (1) clinical trial sample size, (2) calendar time to enroll the trial, (3) total patient screening costs and the total per-patient trial costs, (4) generalizability of trial results, and (5) ethical evaluation of trial eligibility criteria. Items (1)-(3) are amenable to quantitative analysis. We developed the Biomarker Prognostic Enrichment Tool for evaluating biomarkers for prognostic enrichment at varying levels of screening stringency. We demonstrate that both modestly prognostic and strongly prognostic biomarkers can improve trial metrics using Biomarker Prognostic Enrichment Tool. Biomarker Prognostic Enrichment Tool is available as a webtool at http://prognosticenrichment.com and as a package for the R statistical computing platform. In some clinical settings, even biomarkers with modest prognostic performance can be useful for prognostic enrichment. In addition to the quantitative analysis provided by Biomarker Prognostic Enrichment Tool, investigators must consider the generalizability of trial results and evaluate the ethics of trial eligibility criteria.

  9. Longitudinal effects of environmental enrichment on behaviour and physiology of pigs reared on an intensive-stock farm

    Directory of Open Access Journals (Sweden)

    Augusto Vitale

    2011-10-01

    Full Text Available The aim of this paper was to provide a longitudinal evaluation of the effects of physical enrichments on the behaviour and physiology of intensive stock-farming pigs. Twenty-eight crossbred pigs of both sexes, were exposed to four types of enrichments (hemp ropes, steel chains, plastic balls, rubber hoses over a period of eleven weeks. This investigation was based on specific abnormal behaviours and physiological indicators, including hematologic parameters. For behavioural score, focal sampling was used with recording of abnormal behaviours (body-, tail- and ear-biting, belly nosing, running, and interaction with objects (for Enriched pigs. The presence of skin injuries was also recorded. In general, the frequency of abnormal behaviours was significantly reduced in the Enriched group. A timerelated profile appeared in the use of the enrichments. Males showed higher occurrence of skin injuries than females. Physiological measurements, such as levels of complement system, white blood cells and neutrophils, were lower in pigs from the Enriched group. Enriched pigs, as a whole, presented much lower levels of serum DHEA-S concentration over two weeks. The findings of this study show the successful provision of appropriate enrichments to encourage behaviours which may result in satisfactory animal oral interaction with the enriching objects, preventing them biting pen-mates. In this respect, the objects proposed were strongly effective in producing changes in behaviour which could mitigate inadequate conditions, such as the relationship between animal body weight and the available space allowance.

  10. Air-surface exchange measurements of gaseous elemental mercury over naturally enriched and background terrestrial landscapes in Australia

    Directory of Open Access Journals (Sweden)

    G. C. Edwards

    2013-05-01

    Full Text Available This paper presents the first gaseous elemental mercury (GEM air-surface exchange measurements obtained over naturally enriched and background (−1 Hg terrestrial landscapes in Australia. Two pilot field studies were carried out during the Australian autumn and winter periods at a copper-gold-cobalt-arsenic-mercury mineral field near Pulganbar, NSW. GEM fluxes using a dynamic flux chamber approach were measured, along with controlling environmental parameters over three naturally enriched and three background substrates. The enriched sites results showed net emission to the atmosphere and a strong correlation between flux and substrate Hg concentration, with average fluxes ranging from 14 ± 1 ng m−2 h−1 to 113 ± 6 ng m−2 h−1. Measurements at background sites showed both emission and deposition. The average Hg flux from all background sites showed an overall net emission of 0.36 ± 0.06 ng m−2 h−1. Fluxes show strong relationships with temperature, radiation, and substrate parameters. A compensation point of 2.48, representative of bare soils was determined. For periods of deposition, dry deposition velocities ranged from 0.00025 cm s−1 to 0.0083 cm s−1 with an average of 0.0041 ± 0.00018 cm s−1, representing bare soil, nighttime conditions. Comparison of the Australian data to North American data suggests the need for Australian-specific mercury air-surface exchange data representative of Australia's unique climatic conditions, vegetation types, land use patterns and soils.

  11. PWR fuel of high enrichment with erbia and enriched gadolinia

    International Nuclear Information System (INIS)

    Bejmer, Klaes-Håkan; Malm, Christian

    2011-01-01

    Today standard PWR fuel is licensed for operation up to 65-70 MWd/kgU, which in most cases corresponds to an enrichment of more than 5 w/o "2"3"5U. Due to criticality safety reason of storage and transportation, only fuel up to 5 w/o "2"3"5U enrichment is so far used. New fuel storage installations and transportation casks are necessary investments before the reactivity level of the fresh fuel can be significantly increased. These investments and corresponding licensing work takes time, and in the meantime a solution that requires burnable poisons in all pellets of the fresh high-enriched fuel might be used. By using very small amounts of burnable absorber in every pellet the initial reactivity can be reduced to today's levels. This study presents core calculations with fuel assemblies enriched to almost 6 w/o "2"3"5U mixed with a small amount of erbia. Some of the assemblies also contain gadolinia. The results are compared to a reference case containing assemblies with 4.95 w/o "2"3"5U without erbia, utilizing only gadolinia as burnable poison. The comparison shows that the number of fresh fuel assemblies can be reduced by 21% (which increases the batch burnup by 24%) by utilizing the erbia fuel concept. However, increased cost of uranium due to higher enrichment is not fully compensated for by the cost gain due to the reduction of the number assemblies. Hence, the fuel cycle cost becomes slightly higher for the high enrichment erbia case than for the reference case. (author)

  12. Development of on-line uranium enrichment monitor of gaseous UF6 for uranium enrichment plant

    International Nuclear Information System (INIS)

    Lu Xuesheng; Liu Guorong; Jin Huimin; Zhao Yonggang; Li Jinghuai; Hao Xueyuan; Ying Bin; Yu Zhaofei

    2013-01-01

    An on-line enrichment monitor was developed to measure the enrichment of UF 6 , flowing through the processing pipes in uranium enrichment plant. A Nal (Tl) detector was used to measure the count rates of the 185.7 keV γ-ray emitted from 235 U, and the total quantity of uranium was determined from thermodynamic characteristics of gaseous uranium hexafluoride. The results show that the maximum relative standard deviation is less than 1% when the measurement time is 120 s or more and the pressure is more than 2 kPa in the measurement chamber. Uranium enrichment of gaseous uranium hexafluoride in the output end of cascade can be monitored continuously by using the device. It should be effective for nuclear materials accountability verifications and materials balance verification at uranium enrichment plant. (authors)

  13. Visual evoked potentials show strong positive association with intracranial pressure in patients with cryptococcal meningitis

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    Marcelo Adriano da Cunha Silva Vieira

    2015-04-01

    Full Text Available Objective : To verify the relationship between intracranial pressure and flash visual evoked potentials (F-VEP in patients with cryptococcal meningitis. Method The sample included adults diagnosed with cryptococcal meningitis admitted at a reference hospital for infectious diseases. The patients were subjected to F-VEP tests shortly before lumbar puncture. The Pearson’s linear correlation coefficient was calculated and the linear regression analysis was performed. Results : Eighteen individuals were subjected to a total of 69 lumbar punctures preceded by F-VEP tests. At the first lumbar puncture performed in each patient, N2 latency exhibited a strong positive correlation with intracranial pressure (r = 0.83; CI = 0.60 - 0.94; p < 0.0001. The direction of this relationship was maintained in subsequent punctures. Conclusion : The intracranial pressure measured by spinal tap manometry showed strong positive association with the N2 latency F-VEP in patients with cryptococcal meningitis.

  14. Short-term enrichment makes male rats more attractive, more defensive and alters hypothalamic neurons.

    Directory of Open Access Journals (Sweden)

    Rupshi Mitra

    Full Text Available Innate behaviors are shaped by contingencies built during evolutionary history. On the other hand, environmental stimuli play a significant role in shaping behavior. In particular, a short period of environmental enrichment can enhance cognitive behavior, modify effects of stress on learned behaviors and induce brain plasticity. It is unclear if modulation by environment can extend to innate behaviors which are preserved by intense selection pressure. In the present report we investigate this issue by studying effects of relatively short (14-days environmental enrichment on two prominent innate behaviors in rats, avoidance of predator odors and ability of males to attract mates. We show that enrichment has strong effects on both the innate behaviors: a enriched males were more avoidant of a predator odor than non-enriched controls, and had a greater rise in corticosterone levels in response to the odor; and b had higher testosterone levels and were more attractive to females. Additionally, we demonstrate decrease in dendritic length of neurons of ventrolateral nucleus of hypothalamus, important for reproductive mate-choice and increase in the same in dorsomedial nucleus, important for defensive behavior. Thus, behavioral and hormonal observations provide evidence that a short period of environmental manipulation can alter innate behaviors, providing a good example of gene-environment interaction.

  15. Reducing enrichment of fuel for research reactors

    International Nuclear Information System (INIS)

    Kanda, Keiji; Matsuura, Shojiro.

    1980-01-01

    In research reactors, highly enriched uranium (HEU) is used as fuel for their purposes of operation. However, the United States strongly required in 1977 that these HEU should be replaced by low enrichment uranium (LEU) of 20% or less, or even in unavoidable cases, it should be replaced by medium enrichment uranium (MEU). INFCE (International Nuclear Fuel Cycle Evaluation) which started its activity just at that time decided to discuss this problem in the research reactor group of No. 8 sectional committee. Japan has been able to forward the work, taking a leading part in the international opinion because she has taken the countermeasures quickly. INFCE investigated the problem along the lines of policy that the possibility of reducing the degree of enrichment should be limited to the degree in which the core structures and equipments of research reactors will be modified as little as possible, and the change of fuel element geometry will be done within the permissible thermohydrodynamic capacity, and concluded that it might be possible in near future to reduce the degree of enrichment to about 45% MEU, while the reduction to 20% LEU might require considerable research, development and verification. On the other hand, the joint researches by Kyoto University and ANL (Argonne National Laboratory) and by Japan Atomic Energy Research Institute and ANL are being continued. IAEA has edited the guidebook (IAEA-TECDOC-233) for reducing the degree of enrichment for developing countries. (Wakatsuki, Y.)

  16. Extraosseus enrichments in bone scintigraphy

    International Nuclear Information System (INIS)

    Jochens, R.; Schumacher, T.; Amthauer, H.; Wolter, M.; Stock, W.; Stroszczynski, C.; Moersler, J.P.; Eichstaedt, H.

    1996-01-01

    Extraosseus enrichments are common findings in bone scintigraphy. Main causes are artifacts by skin or cloth contamination, paravenous and subcutaneous injection. Physical examination, removal of cloths, skin cleaning or further images in differing projections lead to the correct diagnosis artefact or extraosseous enrichments. Further on, extraosseous enrichments are seen in physiological variants. In different diseases extraosseous enrichments are common, especially in urinary tract, liver and extremities. Further diagnostics, e.g. conventional radiologic procedures, sonography and CT scans, have to be performed. In individual cases side results in bone scintigraphy lead to formerly unknown diagnosis, further diagnostic procedure is influenced decisively. Own cases show for example a cerebral apoplectic insult, formerly unknown liver metastasis or metastasis in extraosseous Ewings's sarcoma. (orig.) [de

  17. Preterm infants fed nutrient-enriched formula until 6 months show improved growth and development.

    Science.gov (United States)

    Jeon, Ga Won; Jung, Yu Jin; Koh, Sun Young; Lee, Yeon Kyung; Kim, Kyung Ah; Shin, Son Moon; Kim, Sung Shin; Shim, Jae Won; Chang, Yun Sil; Park, Won Soon

    2011-10-01

    The purpose of the present study was to determine the effect of feeding nutrient-enriched preterm formula to preterm infants until 6 months' corrected age (CA) on growth and development in the first 18 months of life. Very low-birthweight preterm infants were fed preterm formula until term (40 weeks CA). Infants were then assigned to one of three groups and were fed term formula until 6 months' CA (group 1, n= 29); preterm formula to 3 months' CA and then term formula to 6 months' CA (group 2, n= 30); or preterm formula until 6 months' CA (group 3, n= 31). Anthropometry was performed at term, 3, 6, 9, 12, 15, and at s18 months' CA. Mental and psychomotor development were assessed using the Bayley Scales of Infant Development II at 18 months' CA. Although body weight, length, head circumference and z score for CA at term in group 3 were significantly lower than those of groups 1 and 2, growth rates of these parameters were significantly higher in group 3 up to 18 months CA', as compared to groups 1 and 2. The mental developmental index and psychomotor developmental index of the Bayley test were not significantly different between the three groups. Very low-birthweight preterm infants fed nutrient-enriched preterm formula until 6 months' CA demonstrated significantly improved growth rates for bodyweight, length and head circumference, and comparable mental and psychomotor development throughout the first 18 months of life. © 2011 The Authors. Pediatrics International © 2011 Japan Pediatric Society.

  18. Radiological analysis of plutonium glass batches with natural/enriched boron

    International Nuclear Information System (INIS)

    Rainisch, R.

    2000-01-01

    The disposition of surplus plutonium inventories by the US Department of Energy (DOE) includes the immobilization of certain plutonium materials in a borosilicate glass matrix, also referred to as vitrification. This paper addresses source terms of plutonium masses immobilized in a borosilicate glass matrix where the glass components include both natural boron and enriched boron. The calculated source terms pertain to neutron and gamma source strength (particles per second), and source spectrum changes. The calculated source terms corresponding to natural boron and enriched boron are compared to determine the benefits (decrease in radiation source terms) for to the use of enriched boron. The analysis of plutonium glass source terms shows that a large component of the neutron source terms is due to (a, n) reactions. The Americium-241 and plutonium present in the glass emit alpha particles (a). These alpha particles interact with low-Z nuclides like B-11, B-10, and O-17 in the glass to produce neutrons. The low-Z nuclides are referred to as target particles. The reference glass contains 9.4 wt percent B 2 O 3 . Boron-11 was found to strongly support the (a, n) reactions in the glass matrix. B-11 has a natural abundance of over 80 percent. The (a, n) reaction rates for B-10 are lower than for B-11 and the analysis shows that the plutonium glass neutron source terms can be reduced by artificially enriching natural boron with B-10. The natural abundance of B-10 is 19.9 percent. Boron enriched to 96-wt percent B-10 or above can be obtained commercially. Since lower source terms imply lower dose rates to radiation workers handling the plutonium glass materials, it is important to know the achievable decrease in source terms as a result of boron enrichment. Plutonium materials are normally handled in glove boxes with shielded glass windows and the work entails both extremity and whole-body exposures. Lowering the source terms of the plutonium batches will make the handling

  19. Centrifuge enrichment program

    International Nuclear Information System (INIS)

    Astley, E.R.

    1976-01-01

    Exxon Nuclear has been active in privately funded research and development of centrifuge enrichment technology since 1972. In October of 1975, Exxon Nuclear submitted a proposal to design, construct, and operate a 3000-MT SWU/yr centrifuge enrichment plant, under the provisions of the proposed Nuclear Fuel Assurance Act of 1975. The U.S. Energy Research and Development Administration (ERDA) accepted the proposal as a basis for negotiation. It was proposed to build a 1000-MT SWU/yr demonstration increment to be operational in 1982; and after successful operation for about one year, expand the facilities into a 3000-MT SWU/yr plant. As part of the overall centrifuge enrichment plant, a dedicated centrifuge manufacturing plant would be constructed; sized to support the full 3000-MT SWU/yr plant. The selection of the centrifuge process by Exxon Nuclear was based on an extremely thorough evaluation of current and projected enrichment technology; results show that the technology is mature and the process will be cost effective. The substantial savings in energy (about 93%) from utilization of the centrifuge option rather than gaseous diffusion is a compelling argument. As part of this program, Exxon Nuclear has a large hardware R and D program, plus a prototype centrifuge manufacturing capability in Malta, New York. To provide a full-scale machine and limited cascade test capability, Exxon Nuclear is constructing a $4,000,000 Centrifuge Test Facility in Richland, Washington. This facility was to initiate operations in the Fall of 1976. Exxon Nuclear is convinced that the centrifuge enrichment process is the rational selection for emergence of a commercial enrichment industry

  20. Modular enrichment measurement system for in-situ enrichment assay

    International Nuclear Information System (INIS)

    Stewart, J.P.

    1976-01-01

    A modular enrichment measurement system has been designed and is in operation within General Electric's Nuclear Fuel Fabrication Facility for the in-situ enrichment assay of uranium-bearing materials in process containers. This enrichment assay system, which is based on the ''enrichment meter'' concept, is an integral part of the site's enrichment control program and is used in the in-situ assay of the enrichment of uranium dioxide (UO 2 ) powder in process containers (five gallon pails). The assay system utilizes a commercially available modular counting system and a collimnator designed for compatability with process container transport lines and ease of operator access. The system has been upgraded to include a microprocessor-based controller to perform system operation functions and to provide data acquisition and processing functions. Standards have been fabricated and qualified for the enrichment assay of several types of uranium-bearing materials, including UO 2 powders. The assay system has performed in excess of 20,000 enrichment verification measurements annually and has significantly contributed to the facility's enrichment control program

  1. Critical experiments on an enriched uranium solution system containing periodically distributed strong thermal neutron absorbers

    International Nuclear Information System (INIS)

    Rothe, R.E.

    1996-01-01

    A series of 62 critical and critical approach experiments were performed to evaluate a possible novel means of storing large volumes of fissile solution in a critically safe configuration. This study is intended to increase safety and economy through use of such a system in commercial plants which handle fissionable materials in liquid form. The fissile solution's concentration may equal or slightly exceed the minimum-critical-volume concentration; and experiments were performed for high-enriched uranium solution. Results should be generally applicable in a wide variety of plant situations. The method is called the 'Poisoned Tube Tank' because strong neutron absorbers (neutron poisons) are placed inside periodically spaced stainless steel tubes which separate absorber material from solution, keeping the former free of contamination. Eight absorbers are investigated. Both square and triangular pitched lattice patterns are studied. Ancillary topics which closely model typical plant situations are also reported. They include the effect of removing small bundles of absorbers as might occur during inspections in a production plant. Not taking the tank out of service for these inspections would be an economic advantage. Another ancillary topic studies the effect of the presence of a significant volume of unpoisoned solution close to the Poisoned Tube Tank on the critical height. A summary of the experimental findings is that boron compounds were excellent absorbers, as expected. This was true for granular materials such as Gerstley Borate and Borax; but it was also true for the flexible solid composed of boron carbide and rubber, even though only thin sheets were used. Experiments with small bundles of absorbers intentionally removed reveal that quite reasonable tanks could be constructed that would allow a few tubes at a time to be removed from the tank for inspection without removing the tank from production service

  2. Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders.

    LENUS (Irish Health Repository)

    Anney, Richard J L

    2012-02-01

    Recent genome-wide association studies (GWAS) have implicated a range of genes from discrete biological pathways in the aetiology of autism. However, despite the strong influence of genetic factors, association studies have yet to identify statistically robust, replicated major effect genes or SNPs. We apply the principle of the SNP ratio test methodology described by O\\'Dushlaine et al to over 2100 families from the Autism Genome Project (AGP). Using a two-stage design we examine association enrichment in 5955 unique gene-ontology classifications across four groupings based on two phenotypic and two ancestral classifications. Based on estimates from simulation we identify excess of association enrichment across all analyses. We observe enrichment in association for sets of genes involved in diverse biological processes, including pyruvate metabolism, transcription factor activation, cell-signalling and cell-cycle regulation. Both genes and processes that show enrichment have previously been examined in autistic disorders and offer biologically plausibility to these findings.

  3. Can enrichment make Brazilian tapir spend more time on view to the public?

    Science.gov (United States)

    Dutra, Luísa Mascarenhas Ladeia; Young, Robert John

    2015-01-01

    One common visitor complaint in zoos is that the nonhuman animals are not visible. This problem needs to be resolved without compromising the animals' welfare; environmental enrichment could solve the problem. This study investigated whether enrichment would increase public exposure time of lowland tapir (Tapirus terrestris) in the Belo Horizonte Zoo in Minas Gerais, Brazil. Observations were made before (62 hr) and during (62 hr) the introduction of enrichment using focal animal sampling with instantaneous recording of behavior. The 5 enrichment items were a bamboo fence covered in vines, logs, a sandbox, dry leaves, and bamboo bushes. Before the enrichments were applied, the tapir was not visible to the public for more than 85% of the time. In addition, during the analysis of the enrichment treatment, other variables were considered--such as weekday, time of day, and weather conditions--which could influence the animals' interaction with the enrichments. The enrichments increased and decreased the expression of some behaviors; however, public viewing time of the animals did not increase. Thus, the enrichment applied was not strong enough to overcome the animals' crepuscular behavior.

  4. Analysis of the performance of fuel cells PWR with a single enrichment and radial distribution of enrichments

    International Nuclear Information System (INIS)

    Vargas, S.; Gonzalez, J. A.; Alonso, G.; Del Valle, E.; Xolocostli M, J. V.

    2008-01-01

    One of the main challenges in the design of fuel assemblies is the efficient use of uranium achieving burnt homogeneous of the fuel rods as well as the burnt maximum possible of the same ones to the unload. In the case of the assemblies type PWR has been decided actually for fuel assemblies with a single radial enrichment. The present work has like effect to show the because of this decision, reason why a comparison of the neutronic performance of two fuel cells takes place with the same enrichment average but one of them with radial distribution of enrichment and the other with a single enrichment equal to the average. The results shown in the present study of the behavior of the neutron flow as well as the power distribution through of assembly sustain the because of a single radial enrichment. (Author)

  5. The enriched chromium neutrino source for GALLEX

    International Nuclear Information System (INIS)

    Hartmann, F.X.; Hahn, R.L.

    1991-01-01

    The preparation and study of an intense source of neutrinos in the form of neutron irradiated materials which are enriched in Cr-50 for use in the GALLEX solar neutrino experiment are discussed. Chromyl fluoride gas is enriched in the Cr-50 isotope by gas centrifugation and subsequently converted to a very stable form of chromium oxide. The results of neutron activation analyses of such chromium samples indicate low levels of any long-lived activities, but show that short-lived activities, in particular Na-24, may be of concern. These results show that irradiating chromium oxide enriched in Cr-50 is preferable to irradiating either natural chromium or argon gas as a means of producing a neutrino source to calibrate the GALLEX detector. These results of the impurity level analysis of the enriched chromyl fluoride gas and its conversion to the oxide are also of interest to work in progress by other members of the Collaboration investigating an alternative conversion of the enriched gas to chromium metal. 35 refs., 12 figs., 5 tabs

  6. Comparative studies on mitochondria isolated from neuron-enriched and glia-enriched fractions of rabbit and beef brain.

    Science.gov (United States)

    Hamberger, A; Blomstrand, C; Lehninger, A L

    1970-05-01

    Fractions enriched in neuronal and glial cells were obtained from dispersions of whole beef brain and rabbit cerebral cortex by large-scale density gradient centrifugation procedures. The fractions were characterized by appropriate microscopic observation. Mitochondria were then isolated from these fractions by differential centrifugation of their homogenates. The two different types of mitochondria were characterized with respect to certain enzyme activities, respiratory rate, rate of protein synthesis, and their buoyant density in sucrose gradients. The mitochondria from the neuron-enriched fraction were distinguished by a higher rate of incorporation of amino acids into protein, higher cytochrome oxidase activity, and a higher buoyant density in sucrose density gradients. Mitochondria from the glia-enriched fraction showed relatively high monoamine oxidase and Na(+)- and K(+)-stimulated ATPase activities. The rates of oxidation of various substrates and the acceptor control ratios did not differ appreciably between the two types of mitochondria. The difference in the buoyant density of mitochondria isolated from the neuron-enriched and glia-enriched cell fractions was utilized in attempts to separate neuronal and glial mitochondria from the mixed mitochondria obtained from whole brain homogenates in shallow sucrose gradients. The appearance of two peaks of cytochrome oxidase, monoamine oxidase, and protein concentration in such gradients shows the potential feasibility of such an approach.

  7. Parental Perceptions of STEM Enrichment for Young Children

    Science.gov (United States)

    Tay, Juliana; Salazar, Alissa; Lee, Hyeseong

    2018-01-01

    Most pre-kindergarten (pre-K) and kindergarten curricula are challenging and engaging, but few are strongly grounded in science, technology, engineering, and mathematics (STEM) education. In this study, the authors examined parental perception (N = 55) of the influences of a Saturday STEM enrichment program in one university center on pre-K and…

  8. Uranium enrichment: a competitive market in the future?

    Energy Technology Data Exchange (ETDEWEB)

    Marques, Andre Ferreira; Honaiser, Eduardo Henrique Rangel [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), Sao Paulo, SP (Brazil)]. E-mail: 20-1@ctemsp.mar.mil.br

    2005-07-01

    Uranium enrichment is the costly step in the nuclear fuel cycle. It has born as a an activity for the military in the 40s, financed by governments, such as the United States (US) and the former Soviet Union. Later, other major nations have joined them in the nuclear weapons development. The activity of enrichment was done in each country that developed nuclear weapons, and the nuclear weapons countries, especially the US and Soviet Union, dictated the mined uranium market. In the 70s, with the growth of the commercial use of nuclear energy, uranium enrichment started to be treated as a market, which gradually have structured itself, strongly influenced by the historical background. Today, the market is an oligopoly of four major government-owned (or government-influenced) companies. In this paper, the trends in the enrichment market are identified, focusing on competitiveness. Through the conduction of a market analysis (past and future), and the study of the market structure evolution, a more competitive market is shown, but still influenced by the governmental participation. Competitiveness is dictated by government support, verticalization capacity, and, mainly by technological advantages. (author)

  9. Uranium enrichment: a competitive market in the future?

    International Nuclear Information System (INIS)

    Marques, Andre Ferreira; Honaiser, Eduardo Henrique Rangel

    2005-01-01

    Uranium enrichment is the costly step in the nuclear fuel cycle. It has born as a an activity for the military in the 40s, financed by governments, such as the United States (US) and the former Soviet Union. Later, other major nations have joined them in the nuclear weapons development. The activity of enrichment was done in each country that developed nuclear weapons, and the nuclear weapons countries, especially the US and Soviet Union, dictated the mined uranium market. In the 70s, with the growth of the commercial use of nuclear energy, uranium enrichment started to be treated as a market, which gradually have structured itself, strongly influenced by the historical background. Today, the market is an oligopoly of four major government-owned (or government-influenced) companies. In this paper, the trends in the enrichment market are identified, focusing on competitiveness. Through the conduction of a market analysis (past and future), and the study of the market structure evolution, a more competitive market is shown, but still influenced by the governmental participation. Competitiveness is dictated by government support, verticalization capacity, and, mainly by technological advantages. (author)

  10. Uranium enrichment

    International Nuclear Information System (INIS)

    1990-01-01

    This report looks at the following issues: How much Soviet uranium ore and enriched uranium are imported into the United States and what is the extent to which utilities flag swap to disguise these purchases? What are the U.S.S.R.'s enriched uranium trading practices? To what extent are utilities required to return used fuel to the Soviet Union as part of the enriched uranium sales agreement? Why have U.S. utilities ended their contracts to buy enrichment services from DOE?

  11. Gas-phase UF6 enrichment monitor for enrichment plant safeguards

    International Nuclear Information System (INIS)

    Strittmatter, R.B.; Tape, J.W.

    1980-03-01

    An in-line enrichment monitor is being developed to provide real-time enrichment data for the gas-phase UF 6 feed stream of an enrichment plant. The nondestructive gamma-ray assay method can be used to determine the enrichment of natural UF 6 with a relative precision of better than 1% for a wide range of pressures

  12. Enriching an effect calculus with linear types

    DEFF Research Database (Denmark)

    Egger, Jeff; Møgelberg, Rasmus Ejlers; Simpson, Alex

    2009-01-01

    We define an ``enriched effect calculus'' by conservatively extending  a type theory for computational effects with primitives from linear logic. By doing so, we obtain a generalisation of linear type theory, intended as a formalism for expressing linear aspects of effects. As a worked example, we...... formulate  linearly-used continuations in the enriched effect calculus. These are captured by a fundamental translation of the enriched effect calculus into itself, which extends existing call-by-value and call-by-name linearly-used CPS translations. We show that our translation is involutive. Full...... completeness results for the various linearly-used CPS translations  follow. Our main results, the conservativity of enriching the effect calculus with linear primitives, and the involution property of the fundamental translation, are proved using a category-theoretic semantics for the enriched effect calculus...

  13. Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes

    Directory of Open Access Journals (Sweden)

    Maja Mustapic

    2017-05-01

    Full Text Available Our team has been a pioneer in harvesting extracellular vesicles (EVs enriched for neuronal origin from peripheral blood and using them as a biomarker discovery platform for neurological disorders. This methodology has demonstrated excellent diagnostic and predictive performance for Alzheimer's and other neurodegenerative diseases in multiple studies, providing a strong proof of concept for this approach. Here, we describe our methodology in detail and offer further evidence that isolated EVs are enriched for neuronal origin. In addition, we present evidence that EVs enriched for neuronal origin represent a more sensitive and accurate base for biomarkers than plasma, serum, or non-enriched total plasma EVs. Finally, we proceed to investigate the protein content of EVs enriched for neuronal origin and compare it with other relevant enriched and non-enriched populations of plasma EVs. Neuronal-origin enriched plasma EVs contain higher levels of signaling molecules of great interest for cellular metabolism, survival, and repair, which may be useful as biomarkers and to follow response to therapeutic interventions in a mechanism-specific manner.

  14. Wheat bran promotes enrichment within the human colonic microbiota of butyrate-producing bacteria that release ferulic acid.

    Science.gov (United States)

    Duncan, Sylvia H; Russell, Wendy R; Quartieri, Andrea; Rossi, Maddalena; Parkhill, Julian; Walker, Alan W; Flint, Harry J

    2016-07-01

    Cereal fibres such as wheat bran are considered to offer human health benefits via their impact on the intestinal microbiota. We show here by 16S rRNA gene-based community analysis that providing amylase-pretreated wheat bran as the sole added energy source to human intestinal microbial communities in anaerobic fermentors leads to the selective and progressive enrichment of a small number of bacterial species. In particular, OTUs corresponding to uncultured Lachnospiraceae (Firmicutes) related to Eubacterium xylanophilum and Butyrivibrio spp. were strongly enriched (by five to 160 fold) over 48 h in four independent experiments performed with different faecal inocula, while nine other Firmicutes OTUs showed > 5-fold enrichment in at least one experiment. Ferulic acid was released from the wheat bran during degradation but was rapidly converted to phenylpropionic acid derivatives via hydrogenation, demethylation and dehydroxylation to give metabolites that are detected in human faecal samples. Pure culture work using bacterial isolates related to the enriched OTUs, including several butyrate-producers, demonstrated that the strains caused substrate weight loss and released ferulic acid, but with limited further conversion. We conclude that breakdown of wheat bran involves specialist primary degraders while the conversion of released ferulic acid is likely to involve a multi-species pathway. © 2015 The Authors. Environmental Microbiology published by Society for Applied Microbiology and John Wiley & Sons Ltd.

  15. Thermal profiles, crystallization behaviors and microstructure of diacylglycerol-enriched palm oil blends with diacylglycerol-enriched palm olein.

    Science.gov (United States)

    Xu, Yayuan; Zhao, Xiaoqing; Wang, Qiang; Peng, Zhen; Dong, Cao

    2016-07-01

    To elucidate the possible interaction mechanisms between DAG-enriched oils, this study investigated how mixtures of DAG-enriched palm-based oils influenced the phase behavior, thermal properties, crystallization behaviors and the microstructure in binary fat blends. DAG-enriched palm oil (PO-DAGE) was blended with DAG-enriched palm olein (POL-DAGE) in various percentages (0%, 10%, 30%, 50%, 70%, 90%, 100%). Based on the observation of iso-solid diagram and phase diagram, the binary mixture of PO-DAGE/POL-DAGE showed a better compatibility in comparison with their corresponding original blends. DSC thermal profiles exhibited that the melting and crystallization properties of PO-DAGE/POL-DAGE were distinctively different from corresponding original blends. Crystallization kinetics revealed that PO-DAGE/POL-DAGE blends displayed a rather high crystallization rate and exhibited no spherulitic crystal growth. From the results of polarized light micrographs, PO-DAGE/POL-DAGE blends showed more dense structure with very small needle-like crystals than PO/POL. X-ray diffraction evaluation revealed when POL-DAGE was added in high contents to PO-DAGE, above 30%, β-polymorph dominated, and the mount of β' forms crystals was decreasing. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. The world market-situation for uranium and its enrichment

    International Nuclear Information System (INIS)

    Lurf, G.

    1977-01-01

    The development of the uranium market is described as well as all pertinent facts which may have contributed to the strong rise in uranium prices of the past three years. The policies of countries which may in the future become major uranium exporters are discussed. For the conversion of uranium there is sufficient capacity. However, if construction of new plants is not started soon shortages could occur in the early 80ies. The market for enrichment has characterized in past years by substantial overcapacities. If new enrichment plants are constructed according to present schedules this overcapacity may prevail into the early 90ies. (orig.) [de

  17. Uranium enrichment

    International Nuclear Information System (INIS)

    Rae, H.K.; Melvin, J.G.

    1988-06-01

    Canada is the world's largest producer and exporter of uranium, most of which is enriched elsewhere for use as fuel in LWRs. The feasibility of a Canadian uranium-enrichment enterprise is therefore a perennial question. Recent developments in uranium-enrichment technology, and their likely impacts on separative work supply and demand, suggest an opportunity window for Canadian entry into this international market. The Canadian opportunity results from three particular impacts of the new technologies: 1) the bulk of the world's uranium-enrichment capacity is in gaseous diffusion plants which, because of their large requirements for electricity (more than 2000 kW·h per SWU), are vulnerable to competition from the new processes; 2) the decline in enrichment costs increases the economic incentive for the use of slightly-enriched uranium (SEU) fuel in CANDU reactors, thus creating a potential Canadian market; and 3) the new processes allow economic operation on a much smaller scale, which drastically reduces the investment required for market entry and is comparable with the potential Canadian SEU requirement. The opportunity is not open-ended. By the end of the century the enrichment supply industry will have adapted to the new processes and long-term customer/supplier relationships will have been established. In order to seize the opportunity, Canada must become a credible supplier during this century

  18. Enrichment Mechanism of Semiconducting Single-walled Carbon Nanotubes by Surfactant Amines

    Science.gov (United States)

    Ju, Sang-Yong; Utz, Marcel; Papadimitrakopoulos, Fotios

    2009-01-01

    Utilization of single-walled carbon nanotubes (SWNTs) in high-end applications hinges on separating metallic (met-) from semiconducting (sem-) SWNTs. Surfactant amines, like octadecylamine (ODA) have proven instrumental for the selective extraction of sem-SWNTs from tetrahydrofuran (THF) nanotube suspensions. The chemical shift differences along the tail of an asymmetric, diacetylenic surfactant amine were used to probe the molecular dynamics in the presence and absence of nanotubes via NMR. The results suggest that the surfactant amine head is firmly immobilized onto the nanotube surface together with acidic water, while the aliphatic tail progressively gains larger mobility as it gets farther from the SWNT. X-ray and high-resolution TEM studies indicate that the sem-enriched sample is populated mainly by small nanotube bundles containing ca. three SWNTs. Molecular simulations in conjunction with previously determined HNO3/H2SO4 oxidation depths for met- and sem-SWNTs indicate that the strong pinning of the amine surfactants on the sem-enriched SWNTs bundles is a result of a well-ordered arrangement of nitrate/amine salts separated with a monomolecular layer of H2O. Such continuous 2D arrangement of nitrate/amine salts shields the local environment adjacent to sem-enriched SWNTs bundles and maintains an acidic pH that preserves nanotube oxidation (i.e. SWNTn+). This, in turn, results in strong interactions with charge-balancing NO3- counter ions that through their association with neutralized surfactant amines provide effective THF dispersion and consequent sem-enrichment. PMID:19397291

  19. Super enrichment of Fe-group nuclei in solar flares and their association with large 3He enrichments

    International Nuclear Information System (INIS)

    Anglin, J.D.; Dietrich, W.F.; Simpson, J.A.

    1977-01-01

    ''Fe''/He ratios at approximately 2 MeV/n have been measured in 60 solar flares and periods of enhanced fluxes during the interval 1972-1976. The observed ditribution of ratios is extremely wide with values ranging from approximately 1 to more than 1000 times the solar abundance ratio. In constrast, most of the CHO/He ratios for the same flares lie within a factor 2 of the observed mean value of 2 x 10 -2 . While experimental limitations prevent a complete correlation study of Fe-group and 3 He abundances, comparison of flares with large Fe enrichments with flares with large 3 He enrichments for the period 1969-1976 shows that a 3 He-rich flare is also likely to be rich in iron. We feel that the association of 3 He and Fe enrichments may be explained by a two-stage process in which a preliminary enrichment of heavy nuclei precedes the preferential acceleration of ambient 3 He. Nuclear interactions are ruled out as the principal source of the enriched 3 He. (author)

  20. Advanced enrichment techniques

    International Nuclear Information System (INIS)

    Johnson, A.

    1988-01-01

    BNFL is in a unique position in that it has commercial experience of diffusion enrichment, and of centrifuge enrichment through its associate company Urenco. In addition BNFL is developing laser enrichment techniques as part of a UK development programme in this area. The paper describes the development programme which led to the introduction of competitive centrifuge enrichment technology by Urenco and discusses the areas where improvements have and will continue to be made in the centrifuge process. It also describes the laser development programme currently being undertaken in the UK. The paper concludes by discussing the relative merits of the various methods of uranium enrichment, with particular reference to the enrichment market likely to obtain over the rest of the century

  1. Advanced enrichment techniques

    International Nuclear Information System (INIS)

    Johnson, A.

    1987-01-01

    BNFL is in a unique position in that it has commercial experience of diffusion enrichment, and of centrifuge enrichment through its associate company Urenco. In addition BNFL is developing laser enrichment techniques as part of a UK development programme in this area. The paper describes the development programme which led to the introduction of competitive centrifuge enrichment technology by Urenco and discusses the areas where improvements have and will continue to be made in the centrifuge process. It also describes the laser development programme currently being undertaken in the UK. The paper concludes by discussing the relative merits of the various methods of uranium enrichment, with particular reference to the enrichment market likely to obtain over the rest of the century. (author)

  2. Juvenile psittacine environmental enrichment.

    Science.gov (United States)

    Simone-Freilicher, Elisabeth; Rupley, Agnes E

    2015-05-01

    Environmental enrichment is of great import to the emotional, intellectual, and physical development of the juvenile psittacine and their success in the human home environment. Five major types of enrichment include social, occupational, physical, sensory, and nutritional. Occupational enrichment includes exercise and psychological enrichment. Physical enrichment includes the cage and accessories and the external home environment. Sensory enrichment may be visual, auditory, tactile, olfactory, or taste oriented. Nutritional enrichment includes variations in appearance, type, and frequency of diet, and treats, novelty, and foraging. Two phases of the preadult period deserve special enrichment considerations: the development of autonomy and puberty. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Isotope enrichment

    International Nuclear Information System (INIS)

    Lydtin, H-J.; Wilden, R.J.; Severin, P.J.W.

    1978-01-01

    The isotope enrichment method described is based on the recognition that, owing to mass diffusion and thermal diffusion in the conversion of substances at a heated substrate while depositing an element or compound onto the substrate, enrichment of the element, or a compound of the element, with a lighter isotope will occur. The cycle is repeated for as many times as is necessary to obtain the degree of enrichment required

  4. Enriched uranium cycles in pressurized heavy water reactors

    International Nuclear Information System (INIS)

    Mazzola, A.

    1994-01-01

    A study was made on the substitution of natural uranium with enriched and on plutonium recycle in unmodified PHWRs (pressure vessel reactor). Results clearly show the usefulness of enriched fuel utilisation for both uranium ore consumption (savings of 30% around 1.3% enrichment) and decreasing fuel cycle coasts. This is also due to a better plutonium exploitation during the cycle. On the other hand plutonium recycle in these reactors via MOX-type fuel appears economically unfavourable under any condition

  5. Silver surface enrichment controlled by simultaneous RBS for reliable PIXE analysis of ancient coins

    International Nuclear Information System (INIS)

    Beck, L.; Alloin, E.; Berthier, C.; Reveillon, S.; Costa, V.

    2008-01-01

    Evidence of silver surface enrichment of ancient silver-copper coins has been pointed out in the past years. Surface enrichment can be fortuitous or intentional. In this paper, we have investigated the cleaning procedures usually performed after excavation or in museums. We have shown that chemicals or commercial products routinely used dissolve preferentially the copper phase and consequently contribute to the silver surface enrichment. As a result, surface analyses such as PIXE or XRF can be strongly affected by this effect. By using simultaneously RBS and PIXE, it is possible to check through the silver surface enrichment and then select the reliable measurements, characteristic of the bulk composition. Results on coins recently discovered and mechanically or chemically cleaned are presented

  6. New generation enrichment monitoring technology for gas centrifuge enrichment plants

    International Nuclear Information System (INIS)

    Ianakiev, Kiril D.; Alexandrov, Boian S.; Boyer, Brian D.; Hill, Thomas R.; Macarthur, Duncan W.; Marks, Thomas; Moss, Calvin E.; Sheppard, Gregory A.; Swinhoe, Martyn T.

    2008-01-01

    The continuous enrichment monitor, developed and fielded in the 1990s by the International Atomic Energy Agency, provided a go-no-go capability to distinguish between UF 6 containing low enriched (approximately 4% 235 U) and highly enriched (above 20% 235 U) uranium. This instrument used the 22-keV line from a 109 Cd source as a transmission source to achieve a high sensitivity to the UF 6 gas absorption. The 1.27-yr half-life required that the source be periodically replaced and the instrument recalibrated. The instrument's functionality and accuracy were limited by the fact that measured gas density and gas pressure were treated as confidential facility information. The modern safeguarding of a gas centrifuge enrichment plant producing low-enriched UF 6 product aims toward a more quantitative flow and enrichment monitoring concept that sets new standards for accuracy stability, and confidence. An instrument must be accurate enough to detect the diversion of a significant quantity of material, have virtually zero false alarms, and protect the operator's proprietary process information. We discuss a new concept for advanced gas enrichment assay measurement technology. This design concept eliminates the need for the periodic replacement of a radioactive source as well as the need for maintenance by experts. Some initial experimental results will be presented.

  7. Technical problems in case of utilizing uranium of medium enrichment for a research reactor

    International Nuclear Information System (INIS)

    Kanda, Keiji; Shibata, Shun-ichi

    1979-01-01

    Usually, highly enriched uranium of 90 - 93% is used for research reactors, but the US government proposed the strong policy to use low enriched uranium of the uranium of medium enrichment in unavoidable case from the viewpoint of the resistance to nuclear proliferation in November, 1977. This policy is naturally applied to Japan also. The export of highly enriched uranium will be permitted only when the President approves it after the technical and economical evaluations by the government. The Kyoto University high flux reactor has the features which are not seen in other research reactors, such as medical irradiation, and it is hard to attain the objectives of researches unless HEU is used. The application for the export of HEU was accepted in February, 1978. The nuclear characteristics of the KUHFR when medium or low enriched uranium is used, the criticality experiment in the KUCA using the uranium of medium enrichment, and the burning test on the uranium fuel plates of medium enrichment are described. The research project to lower the degree of enrichment in the fuel for research and test reactors is expected to be continued down to less than 20%. The MEU of 45% enrichment will be actually used in 1983. (Kako, I.)

  8. On the enrichment of hydrophobic organic compounds in fog droplets

    Science.gov (United States)

    Valsaraj, K. T.; Thoma, G. J.; Reible, D. D.; Thibodeaux, L. J.

    The unusual degree of enrichment of hydrophobic organics in fogwater droplets reported by several investigators can be interpreted as a result of (a) the effects of temperature correction on the reported enrichment factors, (b) the effects of colloidal organic matter (both filterable and non-filterable) in fog water and (c) the effects of the large air-water interfacial adsorption of neutral hydrophobic organics on the tiny fog droplets. The enrichment factor was directly correlated to the hydrophobicity (or the activity coefficient in water) of the compounds, as indicated by their octanol-water partition constants. Compounds with large octanol-water partition coefficients (high activity coefficients in water) showed the largest enrichment. Available experimental data on the adsorption of hydrophobic compounds at the air-water interface and on colloidal organic carbon were used to show that the large specific air-water interfacial areas of fog droplets contribute significantly to the enrichment factor.

  9. Uranium enrichment plans

    International Nuclear Information System (INIS)

    Thomas, D.C.; Gagne, R.W.

    1978-01-01

    The following topics are covered: the status of the Government's existing uranium enrichment services contracts, natural uranium requirements based on the latest contract information, uncertainty in predicting natural uranium requirements based on uranium enrichment contracts, and domestic and foreign demand assumed in enrichment planning

  10. Uranium-enriched granites in Sweden

    International Nuclear Information System (INIS)

    Wilson, M.R.; Aakerblom, G.

    1980-01-01

    Granites with uranium contents higher than normal occur in a variety of geological settings in the Swedish Precambrian, and represent a variety of granite types and ages. They may have been generated by the anatexis of continental crust or processes occurring at a much greater depth. They commonly show enrichment in F, Sn, W and/or Mo. Only in one case is an important uranium mineralization thought to be directly related to a uranium-enriched granite, while the majority of epigenetic uranium mineralizations with economic potential are related to hydrothermal processes in areas where the bedrock is regionally uranium-enhanced. (author)

  11. Uranium enriched granites in Sweden

    International Nuclear Information System (INIS)

    Wilson, M.R.; Aakerblom, G.

    1980-01-01

    Granites with uranium contents higher than normal occur in a variety of geological settings in the Swedish Precambrian, and represent a variety of granite types and ages. They may have been generated by (1) the anatexis of continental crust (2) processes occurring at a much greater depth. They commonly show enrichement in F, Sn, W and/or Mo. Only in one case is an important uranium mineralization thought to be directly related to a uranium-enriched granite, while the majority of epigenetic uranium mineralizations with economic potential are related to hydrothermal processes in areas where the bedrock is regionally uranium-enhanced. (Authors)

  12. Other enrichment related contracts

    International Nuclear Information System (INIS)

    Hall, J.C.

    1978-01-01

    In addition to long-term enrichment contracts, DOE has other types of contracts: (1) short-term, fixed-commitment enrichment contract; (2) emergency sales agreement for enriched uranium; (3) feed material lease agreement; (4) enriched uranium storage agreement; and (5) feed material usage agreement

  13. Enrichment planting without soil treatment

    Energy Technology Data Exchange (ETDEWEB)

    Hagner, Mats

    1998-12-31

    Where enrichment planting had been carried out with either of the two species Picea abies and Pinus contorta, the survival of the planted seedlings was at least as good as after planting in a normal clear cut area treated with soil scarification. This was in spite of the fact that the seedlings were placed shallow in the humus layer without any soil treatment. However, they were sheltered from insects by treatment before planting. Where enrichment planting was carried out with Pinus sylvestris the survival in dense forest was poor, but in open forest the survival was good. The growth of planted seedlings was enhanced by traditional clearing and soil treatment. However, this was for Pinus sylvestris not enough to compensate for the loss of time, 1-2 years, caused by arrangement of soil scarification. The growth of seedlings planted under crown cover was directly related to basal area of retained trees. However, the variation in height growth among individual seedlings was very big, which meant that some seedlings grow well also under a fairly dense forest cover. The pioneer species Pinus sylvestris reacted more strongly to basal area of retained trees than did the shade tolerant species Picea abies. Enrichment planting seems to be a necessary tool for preserving volume productivity, at places where fairly intensive harvest of mature trees has been carried out in stands of ordinary forest type in central Sweden. If double seedlings, with one Picea abies and one Pinus sylvestris, are used, the probability for long term establishment is enhanced 13 refs, 20 figs, 4 tabs

  14. Characteristics of functional enrichment and gene expression level of human putative transcriptional target genes.

    Science.gov (United States)

    Osato, Naoki

    2018-01-19

    Transcriptional target genes show functional enrichment of genes. However, how many and how significantly transcriptional target genes include functional enrichments are still unclear. To address these issues, I predicted human transcriptional target genes using open chromatin regions, ChIP-seq data and DNA binding sequences of transcription factors in databases, and examined functional enrichment and gene expression level of putative transcriptional target genes. Gene Ontology annotations showed four times larger numbers of functional enrichments in putative transcriptional target genes than gene expression information alone, independent of transcriptional target genes. To compare the number of functional enrichments of putative transcriptional target genes between cells or search conditions, I normalized the number of functional enrichment by calculating its ratios in the total number of transcriptional target genes. With this analysis, native putative transcriptional target genes showed the largest normalized number of functional enrichments, compared with target genes including 5-60% of randomly selected genes. The normalized number of functional enrichments was changed according to the criteria of enhancer-promoter interactions such as distance from transcriptional start sites and orientation of CTCF-binding sites. Forward-reverse orientation of CTCF-binding sites showed significantly higher normalized number of functional enrichments than the other orientations. Journal papers showed that the top five frequent functional enrichments were related to the cellular functions in the three cell types. The median expression level of transcriptional target genes changed according to the criteria of enhancer-promoter assignments (i.e. interactions) and was correlated with the changes of the normalized number of functional enrichments of transcriptional target genes. Human putative transcriptional target genes showed significant functional enrichments. Functional

  15. Study on the radiotoxicology of enriched uranium

    International Nuclear Information System (INIS)

    Zhu Shoupeng; Zheng Siying; Wang Guolin; Wang Chongdao; Cao Genfa

    1987-12-01

    A study on the retentive peculiarity of soluble enriched uranium UO 2 F 2 were observed after iv once or consecutive ip qd x 3d to Wistar male rats. The dynamic retention of radioactivity in the body showed that the enriched uranium UO 2 F 2 was chiefly localized in kidney, and then in skeleton and liver. The radioactivity of the enriched uranium UO 2 F 2 in skeleton rose steadily while the concentratoin in kidney and liver droped. When enriched uranium UO 2 F 2 was accumulated in organism, it caused chromosome aberrations on bone marrow cells. Results indicated that the chromosome aberration rates were elevated when the dose of the enriched uranium UO 2 F 2 was increased, at the same time, the cell division was depressed. Accumulation of insoluble enriched uranium U 3 O 8 in gastrointestinal tract was well described by a two exponential expression. Values of retention estimate for fast component, T 1 = 0.34 d, and for relatively long term component, T 2 = 4.05 d. The deposition of UO 2 F 2 in the intact skin was only 0.16 to 0.18% of the total contaminated UO 2 F 2 . Penetration of the enriched uranium UO 2 F 2 was dominantly increased in abraded skin. This value is about 25 to 32 times as compaired with that in intact skin. Retention of the enriched uranium UO 2 F 2 through abraded skins was dominantly localized in kidney and skeleton

  16. On-Line Enrichment Monitor for UF{sub 6} Gas Centrifuge Enrichment Plant

    Energy Technology Data Exchange (ETDEWEB)

    Ianakiev, K. D.; Boyer, B.; Favalli, A.; Goda, J. M.; Hill, T.; Keller, C.; Lombardi, M.; Paffett, M.; MacArthur, D. W.; McCluskey, C.; Moss, C. E.; Parker, R.; Smith, M. K.; Swinhoe, M. T. [Los Alamos National Laboratory, Los Alamos (United States)

    2012-06-15

    This paper is a continuation of the Advanced Enrichment Monitoring Technology for UF{sub 6} Gas Centrifuge Enrichment Plant (GCEP) work, presented in the 2010 IAEA Safeguards Symposium. Here we will present the system architecture for a planned side-by-side field trial test of passive (186-keV line spectroscopy and pressure-based correction for UF{sub 6} gas density) and active (186-keV line spectroscopy and transmission measurement based correction for UF{sub 6} gas density) enrichment monitoring systems in URENCO's enrichment plant in Capenhurst. Because the pressure and transmission measurements of UF{sub 6} are complementary, additional information on the importance of the presence of light gases and the UF{sub 6} gas temperature can be obtained by cross-correlation between simultaneous measurements of transmission, pressure and 186-keV intensity. We will discuss the calibration issues and performance in the context of accurate, on-line enrichment measurement. It is hoped that a simple and accurate on-line enrichment monitor can be built using the UF{sub 6} gas pressure provided by the Operator, based on online mass spectrometer calibration, assuming a negligible (a small fraction of percent) contribution of wall deposits. Unaccounted-for wall deposits present at the initial calibration will lead to unwanted sensitivity to changes in theUF{sub 6} gas pressure and thus to error in the enrichment results. Because the accumulated deposits in the cascade header pipe have been identified as an issue for Go/No Go measurements with the Cascade Header Enrichment Monitor (CHEM) and Continuous Enrichment Monitor (CEMO), it is important to explore their effect. Therefore we present the expected uncertainty on enrichment measurements obtained by propagating the errors introduced by deposits, gas density, etc. and will discuss the options for a deposit correction during initial calibration of an On-Line Enrichment Monitor (OLEM).

  17. Environmental enrichment brings a beneficial effect on beam walking and enhances the migration of doublecortin-positive cells following striatal lesions in rats.

    Science.gov (United States)

    Urakawa, S; Hida, H; Masuda, T; Misumi, S; Kim, T-S; Nishino, H

    2007-02-09

    Rats raised in an enriched environment (enriched rats) have been reported to show less motor dysfunction following brain lesions, but the neuronal correlates of this improvement have not been well clarified. The present study aimed to elucidate the effect of chemical brain lesions and environmental enrichment on motor function and lesion-induced neurogenesis. Three week-old, recently weaned rats were divided into two groups: one group was raised in an enriched environment and the other group was raised in a standard cage for 5 weeks. Striatal damage was induced at an age of 8 weeks by injection of the neuro-toxins 6-hydroxydopamine (6-OHDA) or quinolinic acid (QA) into the striatum, or by injection of 6-OHDA into the substantia nigra (SN), which depleted nigrostriatal dopaminergic innervation. Enriched rats showed better performance on beam walking compared with those raised in standard conditions, but both groups showed similar forelimb use asymmetry in a cylinder test. The number of bromodeoxyuridine-labeled proliferating cells in the subventricular zone was increased by a severe striatal lesion induced by QA injection 1 week after the lesion, but decreased by injection of 6-OHDA into the SN. Following induction of lesions by striatal injection of 6-OHDA or QA, the number of cells positive for doublecortin (DCX) was strongly increased in the striatum; however, there was no change in the number of DCX-positive cells following 6-OHDA injection into the SN. Environmental enrichment enhanced the increase of DCX-positive cells with migrating morphology in the dorsal striatum. In enriched rats, DCX-positive cells traversed the striatal parenchyma far from the corpus callosum and lateral ventricle. DCX-positive cells co-expressed an immature neuronal marker, polysialylated neural cell adhesion molecule, but were negative for a glial marker. These data suggest that environmental enrichment improves motor performance on beam walking and enhances neuronal migration toward

  18. Stagnation and Storage of Strongly Depleted Melts in Slow-Ultraslow Spreading Oceans: Evidence from the Ligurian Tethys

    Science.gov (United States)

    Piccardo, Giovanni; Guarnieri, Luisa; Padovano, Matteo

    2013-04-01

    Our studies of Alpine-Apennine ophiolite massifs (i.e., Lanzo, Voltri, Ligurides, Corsica) show that the Jurassic Ligurian Tethys oceanic basin was a slow-ultraslow spreading basin, characterized by the exposures on the seafloor of mantle peridotites with extreme compositional variability. The large majority of these peridotites are made of depleted spinel harzburgites and plagioclase peridotites. The former are interpreted as reactive peridotites formed by the reactive percolation of under-saturated, strongly trace element depleted asthenospheric melts migrated by porous flow through the mantle lithosphere. The latter are considered as refertilized peridotites formed by peridotite impregnation by percolated silica-saturated, strongly trace element depleted melts. Strongly depleted melts were produced as low-degrees, single melt increments by near fractional melting of the passively upwelling asthenosphere during the rifting stage of the basin. They escaped single melt increment aggregation, migrated isolated through the mantle lithosphere by reactive porous or channeled flow before oceanic opening, and were transformed into silica-saturated derivative liquids that underwent entrapment and stagnation in the shallow mantle lithosphere forming plagioclase-enriched peridotites. Widespread small bodies of strongly depleted gabbro-norites testify for the local coalescence of these derivative liquids. These melts never reached the surface (i.e., the hidden magmatism), since lavas with their composition have never been found in the basin. Subsequently, aggregated MORB melts upwelled within replacive dunite channels (as evidenced by composition of magmatic clinopyroxenes in dunites), intruded at shallow levels as olivine gabbro bodies and extruded as basaltic lavas, to form the crustal rocks of the oceanic lithosphere (i.e., the oceanic magmatism). Km-scale bodies of MORB olivine gabbros were intruded into the plagioclase-enriched peridotites, which were formed in the

  19. Computational fluid mechanics in R and D on uranium enrichment

    International Nuclear Information System (INIS)

    Soubbaramayer, O.

    1988-01-01

    Uranium enrichment represents an essential link in the cycle of nuclear fuels for power production. There are many processes of uranium enrichment, but three of them dominate the nuclear history as well in the past (Gaseous diffusion and centrifugation) as in the present (Laser process). The important role played by the Numerical Fluid Mechanics in the three processes is pointed out. The type of problem raised by Gaseous Diffusion is Channel Flow with wall suction, by Centrifugation, flow of a Compressible gas in a strongly rotating cylinder (Stewartson and Ekman layers) and by Laser process, Thermocapillary-buoyancy flow of a molten metal in an evaporation crucible. The methods and results in these problems are reviewed. 18 refs, 11 figs

  20. Enrichment of boron 10

    International Nuclear Information System (INIS)

    Coutinho, C.M.M.; Rodrigues Filho, J.S.R.; Umeda, K.; Echternacht, M.V.

    1990-01-01

    A isotopic separation pilot plant with five ion exchange columns interconnected in series were designed and built in the IEN. The columns are charged with a strong anionic resin in its alkaline form. The boric acid solution is introduced in the separation columns until it reaches a absorbing zone length which is sufficient to obtain the desired boron-10 isotopic concentration. The boric acid absorbing zone movement is provided by the injection of a diluted hydrochloric acid solution, which replace the boric acid throughout the columns. The absorbing zone equilibrium length is proportional to its total length. The enriched boron-10 and the depleted boron are located in the final boundary and in the initial position of the absorbing zones, respectively. (author)

  1. Subtle Gardeners: Inland Predators Enrich Local Topsoils and Enhance Plant Growth.

    Science.gov (United States)

    Fedriani, José M; Garrote, Pedro José; Delgado, María del Mar; Penteriani, Vincenzo

    2015-01-01

    Inland vertebrate predators could enrich of nutrients the local top soils in the area surrounding their nests and dens by depositing faeces, urine, and prey remains and, thus, alter the dynamics of plant populations. Surprisingly, and in contrast with convincing evidence from coastal habitats, whether and how this phenomenon occurs in inland habitats is largely uncertain even though these habitats represent a major fraction of the earth's surface. We investigated during two consecutive breeding seasons the potential enrichment of the top-soils associated with inland ground-nesting eagle owls Bubo bubo, as well as its possible consequences in the growth of two common annual grasses in southern Spain. Top-soils associated with owl nests differed strongly and significantly from control top-soils in chemical parameters, mainly fertility-related properties. Specifically, levels of available phosphorus, total nitrogen, organic matter, and available potassium were 49.1, 5.6, 3.1, and 2.7 times higher, respectively, in top-soils associated with owl nests as compared to control top-soils. Germination experiments in chambers indicated that nutrient enrichment by nesting owls enhanced seedling growth in both annual grasses (Phalaris canariensis and Avena sativa), with seedling size being 1.4-1.3 times higher in owl nest top-soils than in control top-soils. Our experimental study revealed that pervasive inland, predatory birds can profoundly enrich the topsoil around their nests and, thus, potentially enhance local vegetation growth. Because diverse inland vertebrate predators are widespread in most habitats they have a strong potential to enhance spatial heterogeneity, impinge on plant communities, and exert an overlooked effect on primary productivity worldwide.

  2. Subtle Gardeners: Inland Predators Enrich Local Topsoils and Enhance Plant Growth.

    Directory of Open Access Journals (Sweden)

    José M Fedriani

    Full Text Available Inland vertebrate predators could enrich of nutrients the local top soils in the area surrounding their nests and dens by depositing faeces, urine, and prey remains and, thus, alter the dynamics of plant populations. Surprisingly, and in contrast with convincing evidence from coastal habitats, whether and how this phenomenon occurs in inland habitats is largely uncertain even though these habitats represent a major fraction of the earth's surface. We investigated during two consecutive breeding seasons the potential enrichment of the top-soils associated with inland ground-nesting eagle owls Bubo bubo, as well as its possible consequences in the growth of two common annual grasses in southern Spain. Top-soils associated with owl nests differed strongly and significantly from control top-soils in chemical parameters, mainly fertility-related properties. Specifically, levels of available phosphorus, total nitrogen, organic matter, and available potassium were 49.1, 5.6, 3.1, and 2.7 times higher, respectively, in top-soils associated with owl nests as compared to control top-soils. Germination experiments in chambers indicated that nutrient enrichment by nesting owls enhanced seedling growth in both annual grasses (Phalaris canariensis and Avena sativa, with seedling size being 1.4-1.3 times higher in owl nest top-soils than in control top-soils. Our experimental study revealed that pervasive inland, predatory birds can profoundly enrich the topsoil around their nests and, thus, potentially enhance local vegetation growth. Because diverse inland vertebrate predators are widespread in most habitats they have a strong potential to enhance spatial heterogeneity, impinge on plant communities, and exert an overlooked effect on primary productivity worldwide.

  3. Uranium Enrichment, an overview

    International Nuclear Information System (INIS)

    Coates, J.H.

    1994-01-01

    This general presentation on uranium enrichment will be followed by lectures on more specific topics including descriptions of enrichment processes and assessments of the prevailing commercial and industrial situations. I shall therefore avoid as much as possible duplications with these other lectures, and rather dwell on: some theoretical aspects of enrichment in general, underlying the differences between statistical and selective processes, a review and comparison between enrichment processes, remarks of general order regarding applications, the proliferation potential of enrichment. It is noteworthy that enrichment: may occur twice in the LWR fuel cycle: first by enriching natural uranium, second by reenriching uranium recovered from reprocessing, must meet LWR requirements, and in particular higher assays required by high burn up fuel elements, bears on the structure of the entire front part of the fuel cycle, namely in the conversion/reconversion steps only involving UF 6 for the moment. (author). tabs., figs., 4 refs

  4. Selective adsorption-desorption method for the enrichment of krypton

    International Nuclear Information System (INIS)

    Yuasa, Y.; Ohta, M.; Watanabe, A.; Tani, A.; Takashima, N.

    1975-01-01

    Selective adsorption-desorption method has been developed as an effective means of enriching krypton and xenon gases. A seriesof laboratory-scale tests were performed to provide some basic data of the method when applied to off-gas streams of nuclear power plants. For the first step of the enrichment process of the experiments, krypton was adsorbed on solid adsorbents from dilute mixtures with air at temperatures ranging from -50 0 C to -170 0 C. After the complete breakthrough was obtained, the adsorption bed was evacuated at low temperature by a vacuum pump. By combining these two steps krypton was highly enriched on the adsorbents, and the enrichment factor for krypton was calculated as the product of individual enrichment factors of each step. Two types of adsorbents, coconut charcoal and molecular sieves 5A, were used. Experimental results showed that the present method gave the greater enrichment factor than the conventional method which used selective adsorption step only. (U.S.)

  5. Comparative study on gene set and pathway topology-based enrichment methods.

    Science.gov (United States)

    Bayerlová, Michaela; Jung, Klaus; Kramer, Frank; Klemm, Florian; Bleckmann, Annalen; Beißbarth, Tim

    2015-10-22

    Enrichment analysis is a popular approach to identify pathways or sets of genes which are significantly enriched in the context of differentially expressed genes. The traditional gene set enrichment approach considers a pathway as a simple gene list disregarding any knowledge of gene or protein interactions. In contrast, the new group of so called pathway topology-based methods integrates the topological structure of a pathway into the analysis. We comparatively investigated gene set and pathway topology-based enrichment approaches, considering three gene set and four topological methods. These methods were compared in two extensive simulation studies and on a benchmark of 36 real datasets, providing the same pathway input data for all methods. In the benchmark data analysis both types of methods showed a comparable ability to detect enriched pathways. The first simulation study was conducted with KEGG pathways, which showed considerable gene overlaps between each other. In this study with original KEGG pathways, none of the topology-based methods outperformed the gene set approach. Therefore, a second simulation study was performed on non-overlapping pathways created by unique gene IDs. Here, methods accounting for pathway topology reached higher accuracy than the gene set methods, however their sensitivity was lower. We conducted one of the first comprehensive comparative works on evaluating gene set against pathway topology-based enrichment methods. The topological methods showed better performance in the simulation scenarios with non-overlapping pathways, however, they were not conclusively better in the other scenarios. This suggests that simple gene set approach might be sufficient to detect an enriched pathway under realistic circumstances. Nevertheless, more extensive studies and further benchmark data are needed to systematically evaluate these methods and to assess what gain and cost pathway topology information introduces into enrichment analysis. Both

  6. Effects of enriched uranium on developing brain damage of neonatal rats

    International Nuclear Information System (INIS)

    Gu Guixiong; Zhu Shoupeng; Wang Liuyi; Yang Shuqin; Zhu Lingli

    2001-01-01

    The model of irradiation-induced brain damage in vivo was settled first of all. The micro-auto-radiographic tracing showed that when the rat's brain at postnatal day after lateral ventricle injection with enriched uranium 235 U the radionuclides were mainly accumulated in the nucleus. At the same time autoradiographic tracks appeared in the cytoplasm and interval between cells. The effects of cerebrum exposure to alpha irradiation by enriched uranium on somatic growth and neuro-behavior development of neonatal rats were examined by determination of multiple parameters. In the growth and development of the neonatal rat's cerebrum exposure to enriched uranium, the somatic growth such as body weight and brain weight increase was lower significantly. The data indicated that the neonatal wistar rats having cerebrum exposure to alpha irradiation by enriched uranium showed delayed growth and abnormal neuro-behavior. The changes of neuron specific enolase (NSE), interleukin-1 β (IL- β), superoxide dismutase (SOD), and endothelin (ET) in cerebellum, cerebral cortex, hippocampus, diencephalons of the rat brain after expose to alpha irradiation by enriched uranium were examined with radioimmunoassay. The results showed that SOD and ET can be elevated by the low dose irradiation of enriched uranium, and can be distinctly inhibited by the high dose. The data in view of biochemistry indicated firstly that alpha irradiation from enriched uranium on the developing brain damage of neonatal rats were of sensibility, fragility and compensation in nervous cells

  7. Effects of enriched uranium on developing brain damage of neonatal rats

    Energy Technology Data Exchange (ETDEWEB)

    Guixiong, Gu; Shoupeng, Zhu; Liuyi, Wang; Shuqin, Yang; Lingli, Zhu [Suzhou Medical College, Suzhou (China)

    2001-04-01

    The model of irradiation-induced brain damage in vivo was settled first of all. The micro-auto-radiographic tracing showed that when the rat's brain at postnatal day after lateral ventricle injection with enriched uranium {sup 235}U the radionuclides were mainly accumulated in the nucleus. At the same time autoradiographic tracks appeared in the cytoplasm and interval between cells. The effects of cerebrum exposure to alpha irradiation by enriched uranium on somatic growth and neuro-behavior development of neonatal rats were examined by determination of multiple parameters. In the growth and development of the neonatal rat's cerebrum exposure to enriched uranium, the somatic growth such as body weight and brain weight increase was lower significantly. The data indicated that the neonatal wistar rats having cerebrum exposure to alpha irradiation by enriched uranium showed delayed growth and abnormal neuro-behavior. The changes of neuron specific enolase (NSE), interleukin-1 {beta} (IL- {beta}), superoxide dismutase (SOD), and endothelin (ET) in cerebellum, cerebral cortex, hippocampus, diencephalons of the rat brain after expose to alpha irradiation by enriched uranium were examined with radioimmunoassay. The results showed that SOD and ET can be elevated by the low dose irradiation of enriched uranium, and can be distinctly inhibited by the high dose. The data in view of biochemistry indicated firstly that alpha irradiation from enriched uranium on the developing brain damage of neonatal rats were of sensibility, fragility and compensation in nervous cells.

  8. Energy consumption of chemical uranium enrichment

    International Nuclear Information System (INIS)

    Miyake, T.; Takeda, K.; Obanawa, H.

    1987-01-01

    A quantitative study of chemical separation energy for enriching uranium-235 by the redox chromatography was conducted. Isotope exchange reactions between U 4+ -UO 2 2+ ions in the enrichment column are maintained by the redox reactions. The chemical separation energy is ultimately supplied by hydrogen and oxygen gas for regenerating redox agents. The redox energy for the isotope separation is theoretically predicted as a function of the dynamic enrichment factor observed in the chromatographic development of uranium adsorption band. Thermodynamic treatments of the equilibrium reactions implies and inverse redox reaction which can be enhanced by the chemical potential of the ion-exchange reaction of oxidant. Experimental results showed 30 to 90% recovery of the redox energy by the inverse reaction. These results will devise a simplified redox chromatography process where a number of columns in one module is reduced

  9. Linking nutrient enrichment, sediment erodibility and biofilms

    Science.gov (United States)

    Conrad, B.; Mahon, R.; Sojka, S. L.

    2014-12-01

    Sediment movement in coastal lagoons affects nutrient flux and primary producer growth. Previous research has shown that sediment erodibility is affected by biofilm concentration and that growth of benthic organisms, which produce biofilm, is affected by nutrient enrichment. However, researchers have not examined possible links between nutrient addition and sediment erodibility. We manipulated nutrient levels in the water column of 16 microcosms filled with homogenized sediment from a shallow coastal lagoon and artificial seawater to determine the effects on biofilm growth, measured through chlorophyll a and colloidal carbohydrate concentrations. Erosion tests using a Gust microcosm were conducted to determine the relationship between sediment erodibility and biofilm concentration. Results show that carbohydrate levels decreased with increasing nutrient enrichment and were unrelated to chlorophyll concentrations and erodibility. The nutrient levels did not predictably affect the chlorophyll levels, with lower chlorophyll concentrations in the control and medium enrichment treatments than the low and high enrichment treatments. Controls on biofilm growth are still unclear and the assumed relationship between carbohydrates and erodibility may be invalid. Understanding how biofilms respond to nutrient enrichment and subsequent effects on sediment erodibility is essential for protecting and restoring shallow coastal systems.

  10. Uranium enrichment

    International Nuclear Information System (INIS)

    Mohrhauer, H.

    1982-01-01

    The separation of uranium isotopes in order to enrich the fuel for light water reactors with the light isotope U-235 is an important part of the nuclear fuel cycle. After the basic principals of isotope separation the gaseous diffusion and the centrifuge process are explained. Both these techniques are employed on an industrial scale. In addition a short review is given on other enrichment techniques which have been demonstrated at least on a laboratory scale. After some remarks on the present situation on the enrichment market the progress in the development and the industrial exploitation of the gas centrifuge process by the trinational Urenco-Centec organisation is presented. (orig.)

  11. United States uranium enrichment policies

    International Nuclear Information System (INIS)

    Roberts, R.W.

    1977-01-01

    ERDA's uranium enrichment program policies governing the manner in which ERDA's enrichment complex is being operated and expanded to meet customer requirements for separative work, research and development activities directed at providing technology alternatives for future enrichment capacity, and establishing the framework for additional domestic uranium enrichment capacity to meet the domestic and foreign nuclear industry's growing demand for enrichment services are considered. The ERDA enrichment complex consists of three gaseous diffusion plants located in Oak Ridge, Tennessee; Paducah, Kentucky; and Portsmouth, Ohio. Today, these plants provide uranium enrichment services for commercial nuclear power generation. These enrichment services are provided under contracts between the Government and the utility customers. ERDA's program involves a major pilot plant cascade, and pursues an advanced isotope separation technique for the late 1980's. That the United States must develop additional domestic uranium enrichment capacity is discussed

  12. Background levels of methane in Mars’ atmosphere show strong seasonal variations

    Science.gov (United States)

    Webster, Christopher R.; Mahaffy, Paul R.; Atreya, Sushil K.; Moores, John E.; Flesch, Gregory J.; Malespin, Charles; McKay, Christopher P.; Martinez, German; Smith, Christina L.; Martin-Torres, Javier; Gomez-Elvira, Javier; Zorzano, Maria-Paz; Wong, Michael H.; Trainer, Melissa G.; Steele, Andrew; Archer, Doug; Sutter, Brad; Coll, Patrice J.; Freissinet, Caroline; Meslin, Pierre-Yves; Gough, Raina V.; House, Christopher H.; Pavlov, Alexander; Eigenbrode, Jennifer L.; Glavin, Daniel P.; Pearson, John C.; Keymeulen, Didier; Christensen, Lance E.; Schwenzer, Susanne P.; Navarro-Gonzalez, Rafael; Pla-García, Jorge; Rafkin, Scot C. R.; Vicente-Retortillo, Álvaro; Kahanpää, Henrik; Viudez-Moreiras, Daniel; Smith, Michael D.; Harri, Ari-Matti; Genzer, Maria; Hassler, Donald M.; Lemmon, Mark; Crisp, Joy; Sander, Stanley P.; Zurek, Richard W.; Vasavada, Ashwin R.

    2018-06-01

    Variable levels of methane in the martian atmosphere have eluded explanation partly because the measurements are not repeatable in time or location. We report in situ measurements at Gale crater made over a 5-year period by the Tunable Laser Spectrometer on the Curiosity rover. The background levels of methane have a mean value 0.41 ± 0.16 parts per billion by volume (ppbv) (95% confidence interval) and exhibit a strong, repeatable seasonal variation (0.24 to 0.65 ppbv). This variation is greater than that predicted from either ultraviolet degradation of impact-delivered organics on the surface or from the annual surface pressure cycle. The large seasonal variation in the background and occurrences of higher temporary spikes (~7 ppbv) are consistent with small localized sources of methane released from martian surface or subsurface reservoirs.

  13. Blueprint for domestic uranium enrichment

    International Nuclear Information System (INIS)

    1981-01-01

    The AEC advisory committee on domestic production of uranium enrichment has studied for more than a year how to achieve the domestic enrichment of uranium by the construction and operation of a commercial enriching plant using centrifugal separation method, and the report was submitted to the Atomic Energy Commission on August 18, 1980. Japan has depended wholly on overseas services for her uranium enrichment needs, but the development of domestic enrichment has been carried on in parallel. The AEC decided to construct a uranium enrichment pilot plant using centrifuges, and it has been forwarded as a national project. The plant is operated by the Power Reactor and Nuclear Fuel Development Corp. since 1979. The capacity of the plant will be raised to approximately 75 ton SWU a year. The centrifuges already operated have provided the first delivery of fuel of about 1 ton for the ATR ''Fugen''. The demand-supply balance of uranium enrichment service, the significance of the domestic enrichment of uranium, the evaluation of uranium enrichment technology, the target for domestic enrichment plan, the measures to promote domestic uranium enrichment, and the promotion of the construction of a demonstration plant are reported. (Kako, I.)

  14. Effect of Trichoderma-enriched organic charcoal in the integrated wood protection strategy.

    Directory of Open Access Journals (Sweden)

    Javier Ribera

    Full Text Available The gradual elimination of chromium from wood preservative formulations results in higher Cu leaching and increased susceptibility to wood decay fungi. Finding a sustainable strategy in wood protection has become of great interest among researchers. The objective of these in vitro studies was to demonstrate the effect of T-720-enriched organic charcoal (biochar against five wood decay basidiomycetes isolated from strongly damaged poles. For this purpose, the antagonistic potential of Trichoderma harzianum (strain T-720 was confirmed among other four Trichoderma spp. against five brown-rot basidiomycetes in dual culture tests. T-720 was genetically transformed and tagged with the green fluorescent protein (GFP in order to study its antagonistic mechanism against wood decay basidiomycetes. It was also demonstrated that T-720 inhibits the oxalic acid production by basidiomycetes, a well-known mechanism used by brown-rot fungi to detoxify Cu from impregnated wood. Additionally, this study evaluated the effect of biochar, alone or in combination with T-720, on Cu leaching by different preservatives, pH stabilization and prevention of wood decay caused by five basidiomycetes. Addition of biochar resulted in a significant Cu binding released from impregnated wood specimens. T-720-enriched biochar showed a significant reduction of wood decay caused by four basidiomycetes. The addition of T-720-enriched biochar to the soil into which utility poles are placed may improve the efficiency of Cr-free wood preservatives.

  15. Goose-mediated nutrient enrichment and planktonic grazer control in arctic freshwater ponds

    NARCIS (Netherlands)

    Van Geest, G. J.; Hessen, D. O.; Spierenburg, P.; Dahl-Hansen, G. A. P.; Christensen, G.; Faerovig, P. J.; Brehm, M.; Loonen, M. J. J. E.; Van Donk, E.

    A dramatic increase in the breeding population of geese has occurred over the past few decades at Svalbard. This may strongly impact the fragile ecosystems of the Arctic tundra because many of the ultra-oligotrophic freshwater systems experience enrichment from goose feces. We surveyed 21 shallow

  16. Uranium enrichment. Enrichment processes

    International Nuclear Information System (INIS)

    Alexandre, M.; Quaegebeur, J.P.

    2009-01-01

    Despite the remarkable progresses made in the diversity and the efficiency of the different uranium enrichment processes, only two industrial processes remain today which satisfy all of enriched uranium needs: the gaseous diffusion and the centrifugation. This article describes both processes and some others still at the demonstration or at the laboratory stage of development: 1 - general considerations; 2 - gaseous diffusion: physical principles, implementation, utilisation in the world; 3 - centrifugation: principles, elementary separation factor, flows inside a centrifuge, modeling of separation efficiencies, mechanical design, types of industrial centrifuges, realisation of cascades, main characteristics of the centrifugation process; 4 - aerodynamic processes: vortex process, nozzle process; 5 - chemical exchange separation processes: Japanese ASAHI process, French CHEMEX process; 6 - laser-based processes: SILVA process, SILMO process; 7 - electromagnetic and ionic processes: mass spectrometer and calutron, ion cyclotron resonance, rotating plasmas; 8 - thermal diffusion; 9 - conclusion. (J.S.)

  17. HEAVY-ELEMENT ENRICHMENT OF A JUPITER-MASS PROTOPLANET AS A FUNCTION OF ORBITAL LOCATION

    International Nuclear Information System (INIS)

    Helled, R.; Schubert, G.

    2009-01-01

    One possible mechanism for giant planet formation is disk instability in which the planet is formed as a result of gravitational instability in the protoplanetary disk surrounding the young star. The final composition and core mass of the planet will depend on the planet's mass, environment, and the planetesimal accretion efficiency. We calculate heavy-element enrichment in a Jupiter-mass protoplanet formed by disk instability at various radial distances from the star, considering different disk masses and surface density distributions. Although the available mass for accretion increases with radial distance (a) for disk solid surface density (σ) functions σ = σ 0 a -α with α 5 years of planetary evolution, when the planet is extended and before gap opening and type II migration take place. The accreted mass is calculated for disk masses of 0.01, 0.05, and 0.1 M sun with α = 1/2, 1, and 3/2. We show that a Jupiter-mass protoplanet can accrete 1-110 M + of heavy elements, depending on the disk properties. Due to the limitation on the accretion timescale, our results provide lower bounds on heavy-element enrichment. Our results can explain the large variation in heavy-element enrichment found in extrasolar giant planets. Since higher disk surface density is found to lead to larger heavy-element enrichment, our model results are consistent with the correlation between heavy-element enrichment and stellar metallicity. Our calculations also suggest that Jupiter could have formed at a larger radial distance than its current location while still accreting the mass of heavy elements predicted by interior models. We conclude that in the disk instability model the final composition of a giant planet is strongly determined by its formation environment. The heavy-element abundance of a giant planet does not discriminate between its origin by either disk instability or core accretion.

  18. Biochemical characterization and anti-inflammatory properties of an isothiocyanate-enriched moringa (Moringa oleifera) seed extract.

    Science.gov (United States)

    Jaja-Chimedza, Asha; Graf, Brittany L; Simmler, Charlotte; Kim, Youjin; Kuhn, Peter; Pauli, Guido F; Raskin, Ilya

    2017-01-01

    Moringa oleifera Lam. is a tropical plant, used for centuries as food and traditional medicine. The aim of this study was to develop, validate and biochemically characterize an isothiocyanate-enriched moringa seed extract (MSE), and to compare the anti-inflammatory effects of MSE-containing moringa isothiocyanate-1 (MIC-1) with a curcuminoid-enriched turmeric extract (CTE), and a material further enriched in its primary phytochemical, curcumin (curcumin-enriched material; CEM). MSE was prepared by incubating ground moringa seeds with water to allow myrosinase-catalyzed enzymatic formation of bioactive MIC-1, the predominant isothiocyanate in moringa seeds. Optimization of the extraction process yielded an extract of 38.9% MIC-1. Phytochemical analysis of MSE revealed the presence of acetylated isothiocyanates, phenolic glycosides unique to moringa, flavonoids, fats and fatty acids, proteins and carbohydrates. MSE showed a reduction in the carrageenan-induced rat paw edema (33% at 500 mg/kg MIC-1) comparable to aspirin (27% at 300 mg/kg), whereas CTE did not have any significant effect. In vitro, MIC-1 at 1 μM significantly reduced the production of nitric oxide (NO) and at 5 μM, the gene expression of LPS-inducible nitric oxide synthase (iNOS) and interleukins 1β and 6 (IL-1β and IL-6), whereas CEM did not show any significant activity at all concentrations tested. MIC-1 (10μM) was also more effective at upregulating the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) target genes NAD(P)H:quinone oxidoreductase 1 (NQO1), glutathione S-transferase pi 1 (GSTP1), and heme oxygenase 1 (HO1) than the CEM. Thus, in contrast to CTE and CEM, MSE and its major isothiocyanate MIC-1 displayed strong anti-inflammatory and antioxidant properties in vivo and in vitro, making them promising botanical leads for the mitigation of inflammatory-mediated chronic disorders.

  19. Biochemical characterization and anti-inflammatory properties of an isothiocyanate-enriched moringa (Moringa oleifera seed extract.

    Directory of Open Access Journals (Sweden)

    Asha Jaja-Chimedza

    Full Text Available Moringa oleifera Lam. is a tropical plant, used for centuries as food and traditional medicine. The aim of this study was to develop, validate and biochemically characterize an isothiocyanate-enriched moringa seed extract (MSE, and to compare the anti-inflammatory effects of MSE-containing moringa isothiocyanate-1 (MIC-1 with a curcuminoid-enriched turmeric extract (CTE, and a material further enriched in its primary phytochemical, curcumin (curcumin-enriched material; CEM. MSE was prepared by incubating ground moringa seeds with water to allow myrosinase-catalyzed enzymatic formation of bioactive MIC-1, the predominant isothiocyanate in moringa seeds. Optimization of the extraction process yielded an extract of 38.9% MIC-1. Phytochemical analysis of MSE revealed the presence of acetylated isothiocyanates, phenolic glycosides unique to moringa, flavonoids, fats and fatty acids, proteins and carbohydrates. MSE showed a reduction in the carrageenan-induced rat paw edema (33% at 500 mg/kg MIC-1 comparable to aspirin (27% at 300 mg/kg, whereas CTE did not have any significant effect. In vitro, MIC-1 at 1 μM significantly reduced the production of nitric oxide (NO and at 5 μM, the gene expression of LPS-inducible nitric oxide synthase (iNOS and interleukins 1β and 6 (IL-1β and IL-6, whereas CEM did not show any significant activity at all concentrations tested. MIC-1 (10μM was also more effective at upregulating the nuclear factor (erythroid-derived 2-like 2 (Nrf2 target genes NAD(PH:quinone oxidoreductase 1 (NQO1, glutathione S-transferase pi 1 (GSTP1, and heme oxygenase 1 (HO1 than the CEM. Thus, in contrast to CTE and CEM, MSE and its major isothiocyanate MIC-1 displayed strong anti-inflammatory and antioxidant properties in vivo and in vitro, making them promising botanical leads for the mitigation of inflammatory-mediated chronic disorders.

  20. Promotion of uranium enrichment business

    International Nuclear Information System (INIS)

    Kurushima, Morihiro

    1981-01-01

    The Committee on Nuclear Power has studied on the basic nuclear power policy, establishing its five subcommittees, entrusted by the Ministry of Nternational Trade and Industry. The results of examination by the subcommittee on uranium enrichment business are given along with a report in this connection by the Committee. In order to establish the nuclear fuel cycle, the aspect of uranium enrichment is essential. The uranium enrichment by centrifugal process has proceeded steadily in Power Reactor and Nuclear Fuel Development Corporation. The following matters are described: the need for domestic uranium enrichment, the outlook for overseas enrichment services and the schedule for establishing domestic enrichment business, the current state of technology development, the position of the prototype enrichment plant, the course to be taken to establish enrichment business the main organization operating the prototype and commercial plants, the system of supplying centrifuges, the domestic conversion of natural uranium the subsidies for uranium enrichment business. (J.P.N.)

  1. The Enrichment and Transfer of Heavy Metals for Two Ferns in Pb-Zn Tailing

    Directory of Open Access Journals (Sweden)

    Mai Jiajie

    2017-01-01

    Full Text Available The enrichment and transfer of 8 heavy metals of Equisetum ramosissimum and Pteris vittata growing naturally close to edge of the sewage pool in Bencun Pb-Zn Tailing, Eastern Guangdong were investigated. The results indicated that the pollution of Cd, Pb, Hg, Zn was very severe in this tailing, followed by Cu and Mn. The potential ecological risk of heavy metals was assessed to be very strong based on soil background values of Guangdong Province and at high risk according to criteria of the second grade State Soil Environmental Quality Standard, and Cd, Hg, Pb were the main factors leading to potential ecological risk. The content of 8 heavy metals in the two ferns did not reach critical content of hyperaccumulator, so neither of them was typical hyperaccumulator, but both had a certain tolerance to these heavy metal pollution. Underground parts of Pteris vittata had an enrichment coefficient above 1 and that of Equisetum ramosissimum had a value near 1, therefore the two ferns could be utilized as potential enrichment plants. The two ferns have strong adaptability to the tailing habitat and can be used as pioneers in ecological restoration of Pb-Zn tailings.

  2. From high enriched to low enriched uranium fuel in research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Van Den Berghe, S.; Leenaers, A.; Koonen, E.; Moons, F.; Sannen, L. [Nuclear Materials Science Institute, SCK.CEN, Boeretang 200, B-2400 Mol (Belgium)

    2010-07-01

    Since the 1970's, global efforts have been going on to replace the high-enriched (>90% {sup 235}U), low-density UAlx research reactor fuel with high-density, low enriched (<20% {sup 235}U) replacements. This search is driven by the attempt to reduce the civil use of high-enriched material because of proliferation risks and terrorist threats. American initiatives, such as the Global Threat Reduction Initiative (GTRI) and the Reduced Enrichment for Research and Test Reactors (RERTR) program have triggered the development of reliable low-enriched fuel types for these reactors, which can replace the high enriched ones without loss of performance. Most success has presently been obtained with U{sub 3}Si{sub 2} dispersion fuel, which is currently used in many research reactors in the world. However, efforts to search for a replacement with even higher density, which will also allow the conversion of some high flux research reactors that currently cannot change to U{sub 3}Si{sub 2} (eg. BR2 in Belgium), have continued and are for the moment mainly directed towards the U(Mo) alloy fuel (7-10 w% Mo). This paper provides an overview of the past efforts and presents the current status of the U(Mo) development. (authors)

  3. From high enriched to low enriched uranium fuel in research reactors

    International Nuclear Information System (INIS)

    Van Den Berghe, S.; Leenaers, A.; Koonen, E.; Moons, F.; Sannen, L.

    2010-01-01

    Since the 1970's, global efforts have been going on to replace the high-enriched (>90% 235 U), low-density UAlx research reactor fuel with high-density, low enriched ( 235 U) replacements. This search is driven by the attempt to reduce the civil use of high-enriched material because of proliferation risks and terrorist threats. American initiatives, such as the Global Threat Reduction Initiative (GTRI) and the Reduced Enrichment for Research and Test Reactors (RERTR) program have triggered the development of reliable low-enriched fuel types for these reactors, which can replace the high enriched ones without loss of performance. Most success has presently been obtained with U 3 Si 2 dispersion fuel, which is currently used in many research reactors in the world. However, efforts to search for a replacement with even higher density, which will also allow the conversion of some high flux research reactors that currently cannot change to U 3 Si 2 (eg. BR2 in Belgium), have continued and are for the moment mainly directed towards the U(Mo) alloy fuel (7-10 w% Mo). This paper provides an overview of the past efforts and presents the current status of the U(Mo) development. (authors)

  4. Uranium enrichment. Industrial and commercial aspect

    International Nuclear Information System (INIS)

    Lamorlette, G.

    1983-01-01

    The uranium enrichment, a key stage in the fuel cycle of light-water nuclear power stations, applies sophisticated and protected techniques in installations on a very large scale. This article shows how there was a sudden change from a monopoly position in production to a severe competition in a market which is depressed today but offers good prospects for the future. It indicates how the enrichment industrialist have adapted themselves to the fluctuations of the demand, while safeguarding the reliability of the rendered service and the necessary security of supplies for the proper development of the nuclear electric power [fr

  5. Uranium enrichment by gas centrifuge

    International Nuclear Information System (INIS)

    Heriot, I.D.

    1988-01-01

    After recalling the physical principles and the techniques of centrifuge enrichment the report describes the centrifuge enrichment programmes of the various countries concerned and compares this technology with other enrichment technologies like gaseous diffusion, laser, aerodynamic devices and chemical processes. The centrifuge enrichment process is said to be able to replace with advantage the existing enrichment facilities in the short and medium term. Future prospects of the process are also described, like recycled uranium enrichment and economic improvements; research and development needs to achieve the economic prospects are also indicated. Finally the report takes note of the positive aspect of centrifuge enrichment as far as safeguards and nuclear safety are concerned. 27 figs, 113 refs

  6. Derived enriched uranium market

    International Nuclear Information System (INIS)

    Rutkowski, E.

    1996-01-01

    The potential impact on the uranium market of highly enriched uranium from nuclear weapons dismantling in the Russian Federation and the USA is analyzed. Uranium supply, conversion, and enrichment factors are outlined for each country; inventories are also listed. The enrichment component and conversion components are expected to cause little disruption to uranium markets. The uranium component of Russian derived enriched uranium hexafluoride is unresolved; US legislation places constraints on its introduction into the US market

  7. Enrichment and assessment of the health risks posed by heavy metals in PM1 in Changji, Xinjiang, China.

    Science.gov (United States)

    Liu, Yu Y; Shen, Ya X; Liu, Cheng; Liu, Hao F

    2017-04-16

    The present study aims to investigate the influence of human activity on heavy metals in a typical arid urban area of China and assess human health risks posed by heavy metals in PM 1 (particles <1.0 μm in diameter) for different people. In this paper, Changji (Xinjiang, China) was selected as the study area, and samples were collected from March 2014 to March 2015. A total 14 elements in PM 1 were quantified using ICP-MS. An enrichment factor (EF) was used to assess the influence of human activity on the contamination of these metals. The results indicated that Mn was not enriched; Co, Cu, Cr, Ni, Tl, and V were slightly enriched; Mo, Pb, and Sb were moderately enriched; and Ag, As, and Cd were strongly enriched. To assess the health risks associated with inhaling PM 1 , the risk assessment code and loss in life expectancy based on the individual metals were calculated. The results showed that the elements Ag, Cu, Mo, Pb, Sb, Tl, and V in PM 1 posed low levels of non-carcinogenic risks, but these metals may still pose risks to certain susceptible populations. In addition, the results also showed that As, Co, and Cr posed an appreciable carcinogenic risk, while Cd and Ni posed low levels of carcinogenic risk. The total predicted loss of life expectancy caused by the three metals As, Co, and Ni was 63.67 d for the elderly, 30.95 d for adult males, 26.62 d for adult females, and 48.22 d for children. Therefore, the safety of the elderly and children exposed to PM 1 should be given more attention than the safety of adults. The results from this study demonstrate that the health risks posed by heavy metals in PM 1 in Changji, Xinjiang, China should be examined.

  8. Profile of World Uranium Enrichment Programs - 2007

    International Nuclear Information System (INIS)

    Laughter, Mark D.

    2007-01-01

    It is generally agreed that the most difficult step in building a nuclear weapon is acquiring weapons grade fissile material, either plutonium or highly enriched uranium (HEU). Plutonium is produced in a nuclear reactor, while HEU is produced using a uranium enrichment process. Enrichment is also an important step in the civil nuclear fuel cycle, in producing low enriched uranium (LEU) for use in fuel for nuclear reactors. However, the same equipment used to produce LEU for nuclear fuel can also be used to produce HEU for weapons. Safeguards at an enrichment plant are the array of assurances and verification techniques that ensure uranium is only enriched to LEU, no undeclared LEU is produced, and no uranium is enriched to HEU or secretly diverted. There are several techniques for enriching uranium. The two most prevalent are gaseous diffusion, which uses older technology and requires a lot of energy, and gas centrifuge separation, which uses more advanced technology and is more energy efficient. Gaseous diffusion plants (GDPs) provide about 40% of current world enrichment capacity, but are being phased out as newer gas centrifuge enrichment plants (GCEPs) are constructed. Estimates of current and future enrichment capacity are always approximate, due to the constant upgrades, expansions, and shutdowns occurring at enrichment plants, largely determined by economic interests. Currently, the world enrichment capacity is approximately 53 million kg-separative work units (SWU) per year, with 22 million in gaseous diffusion and 31 million in gas centrifuge plants. Another 23 million SWU/year of capacity are under construction or planned for the near future, almost entirely using gas centrifuge separation. Other less-efficient techniques have also been used in the past, including electromagnetic and aerodynamic separations, but these are considered obsolete, at least from a commercial perspective. Laser isotope separation shows promise as a possible enrichment technique

  9. Environmental enrichment decreases asphyxia-induced neurobehavioral developmental delay in neonatal rats.

    Science.gov (United States)

    Kiss, Peter; Vadasz, Gyongyver; Kiss-Illes, Blanka; Horvath, Gabor; Tamas, Andrea; Reglodi, Dora; Koppan, Miklos

    2013-11-13

    Perinatal asphyxia during delivery produces long-term disability and represents a major problem in neonatal and pediatric care. Numerous neuroprotective approaches have been described to decrease the effects of perinatal asphyxia. Enriched environment is a popular strategy to counteract nervous system injuries. The aim of the present study was to investigate whether enriched environment is able to decrease the asphyxia-induced neurobehavioral developmental delay in neonatal rats. Asphyxia was induced in ready-to-deliver mothers by removing the pups by caesarian section after 15 min of asphyxia. Somatic and neurobehavioral development was tested daily and motor coordination weekly. Our results show that rats undergoing perinatal asphyxia had a marked developmental delay and worse performance in motor coordination tests. However, pups kept in enriched environment showed a decrease in the developmental delay observed in control asphyctic pups. Rats growing up in enriched environment did not show decrease in weight gain after the first week and the delay in reflex appearance was not as marked as in control rats. In addition, the development of motor coordination was not as strikingly delayed as in the control group. Short-term neurofunctional outcome are known to correlate with long-term deficits. Our results thus show that enriched environment could be a powerful strategy to decrease the deleterious developmental effects of perinatal asphyxia.

  10. Radiometric enrichment of nonradioactive ores

    International Nuclear Information System (INIS)

    Mokrousov, V.A.; Lileev, V.A.

    1979-01-01

    Considered are the methods of mineral enrichment based on the use of the radioation of various types. The physical essence of enrichment processes is presented, their classification is given. Described are the ore properties influencing the efficiency of radiometric enrichment, methods of the properties study and estimation of ore enrichment. New possibilities opened by radiometric enrichment in the technology of primary processing of mineral raw materials are elucidated. A considerable attention is paid to the main and auxiliary equipment for radiometric enrichment. The foundations of the safety engineering are presented in a brief form. Presented are also results of investigations and practical works in the field of enrichment of ores of non-ferrous, ferrous and non-metallic minerals with the help of radiometric methods

  11. Building a Team of Passionate Callers to Enrich Education in Croatia

    Science.gov (United States)

    Gojsic, Jasenka; Magzan, Masa

    2010-01-01

    This article is about a group of eight people joined by a common idea--a strong call to enrich education in Croatia so that it motivates leadership and empowers children. Through use of philosophy and methodology of Appreciative Inquiry, this informal group of people has gradually developed into the core team of a potential national movement.…

  12. 77 FR 14838 - General Electric-Hitachi Global Laser Enrichment LLC, Commercial Laser-Based Uranium Enrichment...

    Science.gov (United States)

    2012-03-13

    ... Laser Enrichment LLC, Commercial Laser-Based Uranium Enrichment Facility, Wilmington, North Carolina... a license to General Electric-Hitachi Global Laser Enrichment LLC (GLE or the applicant) to authorize construction of a laser-based uranium enrichment facility and possession and use of byproduct...

  13. Isotopically enriched structural materials in nuclear devices

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, L.W.G., E-mail: Lee.Morgan@ccfe.ac.uk [CCFE, Culham Science Centre, Abingdon, Oxfordshire OX14 3DB (United Kingdom); Shimwell, J. [CCFE, Culham Science Centre, Abingdon, Oxfordshire OX14 3DB (United Kingdom); Department of Physics and Astronomy, University of Sheffield, Hicks Building, Hounsfield Road, Sheffield S3 7RH (United Kingdom); Gilbert, M.R. [CCFE, Culham Science Centre, Abingdon, Oxfordshire OX14 3DB (United Kingdom)

    2015-01-15

    Highlights: • C-B analysis of isotopic enrichment of structural materials is presented. • Some, previously, prohibited elements could be used as alloying elements in LAM's. • Adding enriched molybdenum and nickel, to EUROFER, could increase availability. • Isotope enrichment for EUROFER could be cost-effective. • Isotopically enriching copper, in CuCrZr, can reduce helium production by 50%. - Abstract: A large number of materials exist which have been labeled as low activation structural materials (LAM). Most often, these materials have been designed in order to substitute-out or completely remove elements that become activated and contribute significantly to shut-down activity after being irradiated by neutrons in a reactor environment. To date, one of the fundamental principles from which LAMs have been developed is that natural elemental compositions are the building blocks of LAMs. Thus, elements such as Co, Al, Ni, Mo, Nb, N and Cu that produce long-lived decay products are significantly reduced or removed from the LAM composition. These elements have an important part to play in the composition of steels and the removal/substitution can have a negative impact on materials properties such as yield stress and fracture toughness. This paper looks in more detail at whether using isotopic selection of the more mechanically desirable, but prohibited due to activation, elements can improve matters. In particular, this paper focuses on the activation of Eurofer. Carefully chosen isotopically enriched elements, which are normally considered to be on the prohibited element list, are added to EUROFER steel as potential alloying elements. The EUROFER activation results show that some prohibited elements can be used as alloying elements in LAM steels, providing the selected isotopes do not have a significant impact on waste disposal rating or shut-down dose. The economic implications of isotopically enriching elements and the potential implications for

  14. Successful enrichment of the ubiquitous freshwater acI Actinobacteria.

    Science.gov (United States)

    Garcia, Sarahi L; McMahon, Katherine D; Grossart, Hans-Peter; Warnecke, Falk

    2014-02-01

    Actinobacteria of the acI lineage are often the numerically dominant bacterial phylum in surface freshwaters, where they can account for > 50% of total bacteria. Despite their abundance, there are no described isolates. In an effort to obtain enrichment of these ubiquitous freshwater Actinobacteria, diluted freshwater samples from Lake Grosse Fuchskuhle, Germany, were incubated in 96-well culture plates. With this method, a successful enrichment containing high abundances of a member of the lineage acI was established. Phylogenetic classification showed that the acI Actinobacteria of the enrichment belonged to the acI-B2 tribe, which seems to prefer acidic lakes. This enrichment grows to low cell densities and thus the oligotrophic nature of acI-B2 was confirmed. © 2013 Society for Applied Microbiology and John Wiley & Sons Ltd.

  15. Study on behaviors and performances of universal N-glycopeptide enrichment methods.

    Science.gov (United States)

    Xue, Yu; Xie, Juanjuan; Fang, Pan; Yao, Jun; Yan, Guoquan; Shen, Huali; Yang, Pengyuan

    2018-04-16

    Glycosylation is a crucial process in protein biosynthesis. However, the analysis of glycopeptides through MS remains challenging due to the microheterogeneity and macroheterogeneity of the glycoprotein. Selective enrichment of glycopeptides from complex samples prior to MS analysis is essential for successful glycoproteome research. In this work, we systematically investigated the behaviors and performances of boronic acid chemistry, ZIC-HILIC, and PGC of glycopeptide enrichment to promote understanding of these methods. We also optimized boronic acid chemistry and ZIC-HILIC enrichment methods and applied them to enrich glycopeptides from mouse liver. The intact N-glycopeptides were interpreted using the in-house analysis software pGlyco 2.0. We found that boronic acid chemistry in this study preferred to capture glycopeptides with high mannose glycans, ZIC-HILIC enriched most N-glycopeptides and did not show significant preference during enrichment and PGC was not suitable for separating glycopeptides with a long amino acid sequence. We performed a detailed study on the behaviors and performances of boronic acid chemistry, ZIC-HILIC, and PGC enrichment methods and provide a better understanding of enrichment methods for further glycoproteomics research.

  16. TRIGA low enrichment fuel

    International Nuclear Information System (INIS)

    Gietzen, A.

    1993-01-01

    Sixty TRIGA reactors have been sold and the earliest of these are now passing twenty years of operation. All of these reactors use the uranium zirconium hydride fuel (UZrH) which provides certain unique advantages arising out of its large prompt negative temperature coefficient, very low fission product release, and high temperature capability. Eleven of these Sixty reactors are conversions from plate fuel to TRIGA fuel which were made as a result of these advantages. With only a few exceptions, TRIGA reactors have always used low-enriched uranium (LEU) fuel with an enrichment of 19.9%. The exceptions have either been converted from the standard low-enriched fuel to the 70% enriched FLIP fuel in order to achieve extended lifetime, or are higher powered reactors which were designed for long life using 93%-enriched uranium during the time when the use and export of highly enriched uranium (HEU) was not restricted. The advent of international policies focusing attention on nonproliferation and safeguards made the HEU fuels obsolete. General Atomic immediately undertook a development effort (nearly two years ago) in order to be in a position to comply with these policies for all future export sales and also to provide a low-enriched alternative to fully enriched plate-type fuels. This important work was subsequently partially supported by the U.S. Department of Energy. The laboratory and production tests have shown that higher uranium densities can be achieved to compensate for reducing the enrichment to 20%, and that the fuels maintain the characteristics of the very thoroughly proven standard TRIGA fuels. In May of 1978, General Atomic announced that these fuels were available for TRIGA reactors and for plate-type reactors with power levels up to 15 MW with General Atomic's standard commercial warranty

  17. TRIGA low enrichment fuel

    International Nuclear Information System (INIS)

    Gietzen, A.

    1993-01-01

    Sixty TRIGA reactors have been sold and the earliest of these are now passing twenty years of operation. All of these reactors use the uranium-zirconium hydride fuel (UZrH) which provides certain unique advantages arising out of its large prompt negative temperature coefficient, very low fission product release, and high temperature capability. Eleven of these Sixty reactors are conversions from plate fuel to TRIGA fuel which were made as a result of these advantages. With only a few exceptions, TRIGA reactors have always used low-enriched-uranium (LEU) fuel with an enrichment of 19.9%. The exceptions have either been converted from the standard low-enriched fuel to the 70% enriched FLIP fuel in order to achieve extended lifetime, or are higher powered reactors which were designed for long life using 93%-enriched uranium during the time when the use and export of highly enriched uranium (HEU) was not restricted. The advent of international policies focusing attention on nonproliferation and safeguards made the HEU fuels obsolete. General Atomic immediately undertook a development effort (nearly two years ago) in order to be in a position to comply with these policies for all future export sales and also to provide a low-enriched alternative to fully enriched plate-type fuels. This important work was subsequently partially supported by the U.S. Department of Energy. The laboratory and production tests have shown that higher uranium densities can be achieved to compensate for reducing the enrichment to 20%, and that the fuels maintain the characteristics of the very thoroughly proven standard TRIGA fuels. In May of 1978, General Atomic announced that these fuels were available for TRIGA reactors and for plate-type reactors with power levels up to 15 MW with GA's standard commercial warranty

  18. Turkey's regulatory plans for high enriched to low enriched conversion of TR-2 reactor core

    International Nuclear Information System (INIS)

    Guelol Oezdere, Oya

    2003-01-01

    Turkey is a developing country and has three nuclear facilities two of which are research reactors and one pilot fuel production plant. One of the two research reactors is TR-2 which is located in Cekmece site in Istanbul. TR-2 Reactor's core is composed of both high enriched and low enriched fuel and from high enriched to low enriched core conversion project will take place in year 2005. This paper presents the plans for drafting regulations on the safety analysis report updates for high enriched to low enriched core conversion of TR-2 reactor, the present regulatory structure of Turkey and licensing activities of nuclear facilities. (author)

  19. High enrichment to low enrichment core's conversion. Technical securities

    International Nuclear Information System (INIS)

    Abbate, P.; Madariaga, M.R.

    1990-01-01

    This work presents the fulfillment of the technical securities subscribed by INVAP S.E. for the conversion of a high enriched uranium core. The reactor (of 5 thermal Mw), built in the 50's and 60's, is of the 'swimming pool' type, with light water and fuel elements of the curve plates MTR type, enriched at 93.15 %. These are neutronic and thermohydraulic securities. (Author) [es

  20. Enrichment Rescues Contextual Discrimination Deficit Associated With Immediate Shock

    Science.gov (United States)

    Clemenson, Gregory D.; Lee, Star W.; Deng, Wei; Barrera, Vanessa R.; Iwamoto, Kei S.; Fanselow, Michael S.; Gage, Fred H.

    2015-01-01

    Adult animals continue to modify their behavior throughout life, a process that is highly influenced by past experiences. To shape behavior, specific mechanisms of neural plasticity to learn, remember, and recall information are required. One of the most robust examples of adult plasticity in the brain occurs in the dentate gyrus (DG) of the hippocampus, through the process of adult neurogenesis. Adult neurogenesis is strongly upregulated by external factors such as voluntary wheel running (RUN) and environmental enrichment (EE); however, the functional differences between these two factors remain unclear. Although both manipulations result in increased neurogenesis, RUN dramatically increases the proliferation of newborn cells and EE promotes their survival. We hypothesize that the method by which these newborn neurons are induced influences their functional role. Furthermore, we examine how EE-induced neurons may be primed to encode and recognize features of novel environments due to their previous enrichment experience. Here, we gave mice a challenging contextual fear-conditioning (FC) procedure to tease out the behavioral differences between RUN-induced neurogenesis and EE-induced neurogenesis. Despite the robust increases in neurogenesis seen in the RUN mice, we found that only EE mice were able to discriminate between similar contexts in this task, indicating that EE mice might use a different cognitive strategy when processing contextual information. Furthermore, we showed that this improvement was dependent on EE-induced neurogenesis, suggesting a fundamental functional difference between RUN-induced neurogenesis and EE-induced neurogenesis. PMID:25330953

  1. Beta activity of enriched uranium

    International Nuclear Information System (INIS)

    Nambiar, P.P.V.J.; Ramachandran, V.

    1975-01-01

    Use of enriched uranium as reactor fuel necessitates its handling in various forms. For purposes of planning and organising radiation protection measures in enriched uranium handling facilities, it is necessary to have a basic knowledge of the radiation status of enriched uranium systems. The theoretical variations in beta activity and energy with U 235 enrichment are presented. Depletion is considered separately. Beta activity build up is also studied for two specific enrichments, in respect of which experimental values for specific alpha activity are available. (author)

  2. Centrifugation. A theoretical study of oxygen enrichment by centrifugation

    Energy Technology Data Exchange (ETDEWEB)

    Kierkegaard, P.; Raetz, E.

    1998-12-01

    In the present paper we first investigate what happens if we fill a cylinder with air, close it and rotate it. The results show that no matter which peripheral speed is used, it is not possible by means of the radial separation effect alone, to enrich the oxygen concentration from the previous 21% to more then 23.3%, which is of no practical value. In case of a too low enrichment in one centrifuge, the wanted material from this centrifuge can be used as an input for a second centrifuge and so on, in this way forming a cascade of centrifuges. Oxygen will be enriched in each step, until the desired concentration is reached. Cascading was the technology in the very beginning by enrichment plants for uraniumhexaflouride, used for atomic weapons and nuclear power plants. In this study we try to avoid cascading by aiming for higher separation factors. Therefore, we next investigate the possibilities of using a countercurrent centrifuge where in principle the enriched gas is subjected to several centrifugation in the same centrifuge. The calculations show, that in this way it is possible to produce nearly a 100% pure oxygen (polluted with some heavier molecules like argon) in one machine. Our third step was to calculate the amount of oxygen produced per hour. Using a countercurrent centrifuge of the Zippe type, 100 cm high and 20 cm in diameter, it is or will be possible in the near future to produce 17 g enriched air per hour enriched to 50% oxygen. That corresponds to processing 1 m{sup 3} atmospherical air in the period of approximately 24 hours. This is not very impressive. Our fourth step was to estimate the amount of power used for producing this amount of oxygen. A rough, but complicated, estimate shows that the power consumption at the production level will be about the double of the consumption used today. The overall conclusion is, that centrifugation as a production method for oxygen (or nitrogen) will not be competitive with the currently used method in the

  3. Isotope enrichment

    International Nuclear Information System (INIS)

    Garbuny, M.

    1979-01-01

    The invention discloses a method for deriving, from a starting material including an element having a plurality of isotopes, derived material enriched in one isotope of the element. The starting material is deposited on a substrate at less than a critical submonatomic surface density, typically less than 10 16 atoms per square centimeter. The deposit is then selectively irradiated by a laser (maser or electronic oscillator) beam with monochromatic coherent radiation resonant with the one isotope causing the material including the one istope to escape from the substrate. The escaping enriched material is then collected. Where the element has two isotopes, one of which is to be collected, the deposit may be irradiated with radiation resonant with the other isotope and the residual material enriched in the one isotope may be evaporated from the substrate and collected

  4. Laser and gas centrifuge enrichment

    Energy Technology Data Exchange (ETDEWEB)

    Heinonen, Olli [Senior Fellow, Belfer Center for Science and International Affairs, Harvard Kennedy School, Cambridge, Massachusetts (United States)

    2014-05-09

    Principles of uranium isotope enrichment using various laser and gas centrifuge techniques are briefly discussed. Examples on production of high enriched uranium are given. Concerns regarding the possibility of using low end technologies to produce weapons grade uranium are explained. Based on current assessments commercial enrichment services are able to cover the global needs of enriched uranium in the foreseeable future.

  5. Enrichment technology. Dependable vendor of gas centrifuges; Enrichment Technology. Zuverlaessiger Lieferant von Gaszentrifugen

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2011-10-15

    Enrichment Technology is an innovative, high-tech company that develops, manufactures and installs gas centrifuges for enriching uranium. In addition, Enrichment Technology designs enrichment plants that use gas centrifuge technology. This technology offers the most efficient and cost-effective method for enriching uranium yet: high-performance, safe technology that dominates the market with a global share of 45 percent. A determining factor in Enrichment Technology's success is its mission: supplying its customers with safe, reliable technology. Production of the centrifuges requires versatile know-how and collaboration between different departments as well as interdisciplinary teams at the various sites. More than 2000 operators at 8 sites in 5 countries contribute their individual knowledge and personal skills in order to produce this exceptional technology. The head office is in Beaconsfield near London and the operational headquarters are in Almelo in the Netherlands. There are other sites in Germany (Juelich und Gronau), Great Britain (Capenhurst) as well as project sites in the USA and France. Capenhurst is where experienced engineers design new enrichment plants and organise their construction. Centrifuge components are manufactured in Almelo and Juelich, while the pipework needed to connect up the centrifuges is produced at the site in Gronau. In Juelich, highly qualified scientists in interdisciplinary teams are continuously researching ways of improving the current centrifuges. Communication between specialists in the fields of chemistry, physics and engineering forms the basis for the company's success and the key to extending this leading position in the global enrichment market. (orig.)

  6. 76 FR 11523 - Atomic Safety and Licensing Board; AREVA Enrichment Services, LLC (Eagle Rock Enrichment Facility...

    Science.gov (United States)

    2011-03-02

    ... and Licensing Board; AREVA Enrichment Services, LLC (Eagle Rock Enrichment Facility); Notice of... Governmental Entities Regarding Environmental Portion of Enrichment Facility Licensing Proceeding February 24.... White. In this 10 CFR part 70 proceeding regarding the request of applicant AREVA Enrichment Services...

  7. 76 FR 34103 - In the Matter of Areva Enrichment Services, LLC (Eagle Rock Enrichment Facility); Notice of...

    Science.gov (United States)

    2011-06-10

    .... 10-899-02-ML-BD01] In the Matter of Areva Enrichment Services, LLC (Eagle Rock Enrichment Facility...'' portion of this proceeding regarding the December 2008 application by AREVA Enrichment Services, LLC (AES... gas centrifuge uranium enrichment facility--denoted as the Eagle Rock Enrichment Facility (EREF)--in...

  8. Network-based functional enrichment

    Directory of Open Access Journals (Sweden)

    Poirel Christopher L

    2011-11-01

    Full Text Available Abstract Background Many methods have been developed to infer and reason about molecular interaction networks. These approaches often yield networks with hundreds or thousands of nodes and up to an order of magnitude more edges. It is often desirable to summarize the biological information in such networks. A very common approach is to use gene function enrichment analysis for this task. A major drawback of this method is that it ignores information about the edges in the network being analyzed, i.e., it treats the network simply as a set of genes. In this paper, we introduce a novel method for functional enrichment that explicitly takes network interactions into account. Results Our approach naturally generalizes Fisher’s exact test, a gene set-based technique. Given a function of interest, we compute the subgraph of the network induced by genes annotated to this function. We use the sequence of sizes of the connected components of this sub-network to estimate its connectivity. We estimate the statistical significance of the connectivity empirically by a permutation test. We present three applications of our method: i determine which functions are enriched in a given network, ii given a network and an interesting sub-network of genes within that network, determine which functions are enriched in the sub-network, and iii given two networks, determine the functions for which the connectivity improves when we merge the second network into the first. Through these applications, we show that our approach is a natural alternative to network clustering algorithms. Conclusions We presented a novel approach to functional enrichment that takes into account the pairwise relationships among genes annotated by a particular function. Each of the three applications discovers highly relevant functions. We used our methods to study biological data from three different organisms. Our results demonstrate the wide applicability of our methods. Our algorithms are

  9. Enrichment plants. A survey of major new uranium enriching projects

    International Nuclear Information System (INIS)

    Kovan, D.

    1976-01-01

    The work enrichment situation is reported. The development of enrichment in the U.S. and in Europe is outlined. A brief description is given of the technology of separation by diffusion and by centrifugation and the advantages and disadvantages of the two processes are compared. Finally the supply and demand situation is briefly considered. (U.K.)

  10. Lipid oxidation in fish oil enriched mayonnaise : Calcium disodium ethylenediaminetetraacetate, but not gallic acid, strongly inhibited oxidative deterioration

    DEFF Research Database (Denmark)

    Jacobsen, Charlotte; Hartvigsen, Karsten; Thomsen, Mikael Holm

    2001-01-01

    The antioxidative effects of gallic acid, EDTA, and extra emulsifier Panodan DATEM TR in mayonnaise enriched with 16% fish oil were investigated. EDTA reduced the formation of free radicals, lipid hydroperoxides, volatiles, and fishy and rancid off-flavors. The antioxidative effect of EDTA...... acid may therefore promote the decomposition of lipid hydroperoxides to volatile oxidation products. Addition of extra emulsifier reduced the lipid hydroperoxide levels but did not influence the level of free radicals or the oxidative flavor deterioration in mayonnaisse; however, it appeared to alter...

  11. Development for analysis system of rods enrichment of nuclear fuels

    International Nuclear Information System (INIS)

    Rojas C, E.L.

    1998-01-01

    Nuclear industry is strongly regulated all over the world and quality assurance is important in every nuclear installation or process related with it. Nuclear fuel manufacture is not the exception. ININ was committed to manufacture four nuclear fuel bundles for the CFE nucleo electric station at Laguna Verde, Veracruz, under General Electric specifications and fulfilling all the requirements of this industry. One of the quality control requisites in nuclear fuel manufacture deals with the enrichment of the pellets inside the fuel bundle rods. To achieve the quality demanded in this aspect, the system described in this work was developed. With this system, developed at ININ it is possible to detect enrichment spikes since 0.4 % in a column of pellets with a 95 % confidence interval and to identify enrichment differences greater than 0.2 % e between homogeneous segments, also with a 95 % confidence interval. ININ delivered the four nuclear fuel bundles to CFE and these were introduced in the core of the nuclear reactor of Unit 1 in the fifth cycle. Nowadays they are producing energy and have shown a correct mechanical performance and neutronic behavior. (Author)

  12. Developments in uranium enrichment

    International Nuclear Information System (INIS)

    Mohrhauer, H.

    1995-01-01

    The enrichment services market is still characterized by overcapacities. While consumption worldwide will rise by some 15% to 39,000 t SWU/a over the next ten years, capacities amount to nearly 50,000 t SWU/a. The price for enrichment services probably has reached its all time low. Prices below U.S. $ 100/kg SWU are not likely to cover costs even of the economically most advanced enrichment processes. Urenco has prepared for the difficult enrichment business in the years to come by streamlining and cost cutting measures. The company intends to hold and increase its share of more than 10% in the world market. The uranium enrichment plant of Gronau will be expanded further. Expansion beyond 1000 t is subject to another permit being granted under the Atomic Energy Act, an application for which was filed in December 1994. Centrifuge technology is the superior enrichment technology, i.e., there is still considerable potential for further development. Construction of enrichment plants employing the centrifuge technology in the United States and in France is being pursued in various phases, from feasibility studies to licensing procedures. Before these plants could be implemented, however, considerable problems of organization would have to be solved, and the market would have to change greatly, respectively. The laser process, at the present time, does not seem to be able to develop into a major industrial competitor. (orig.) [de

  13. Uranium enrichment plans

    International Nuclear Information System (INIS)

    Gagne, R.W.; Thomas, D.C.

    1977-01-01

    The status of existing uranium enrichment contracts in the US is reviewed and expected natural uranium requirements for existing domestic uranium enrichment contracts are evaluated. Uncertainty in natural uranium requirements associated with requirements-type and fixed-commitment type contracts is discussed along with implementation of variable tails assay

  14. The US uranium and enrichment industries: their fall and rise?

    International Nuclear Information System (INIS)

    Sewell, P.G.

    1988-01-01

    Strong government influence, monopolistic practices, free market forces and market orientation to customer needs are the conflicting forces which have shaped the evolution of the uranium and the uranium enrichment industries in the United States. These same factors are likely to continue to dictate to a large extent the future for each of these industries. Both the uranium and the uranium enrichment industries in the USA enjoyed the benefits and suffered the consequences of a monopolistic environment until the dynamics of a free market became prevalent in the 1980s. This resulted in the deterioration of both industries with respect to market share, sales and supply capacity needs. The history and environment of the two industries, the road to recovery for both, and the status and scope of legal and legislative initiatives to address the problems of each industry, are reviewed. (author)

  15. Factors that predict consumer acceptance of enriched processed meats

    OpenAIRE

    Shan, Liran Christine; Henchion, Maeve; De Brún, Aoife; Murrin, Celine; Wall, Patrick G.; Monahan, Frank J.

    2017-01-01

    The study aimed to understand predictors of consumers' purchase intention towards processed meat based functional foods (i.e. enriched processed meat). A cross-sectional survey was conducted with 486 processed meat consumers in spring 2016. Results showed that processed meats were perceived differently in healthiness, with sausage-type products perceived less healthy than cured meat products. Consumers were in general more uncertain than positive about enriched processed meat but differences ...

  16. Profile of World Uranium Enrichment Programs-2009

    International Nuclear Information System (INIS)

    Laughter, Mark D.

    2009-01-01

    It is generally agreed that the most difficult step in building a nuclear weapon is acquiring fissile material, either plutonium or highly enriched uranium (HEU). Plutonium is produced in a nuclear reactor, whereas HEU is produced using a uranium enrichment process. Enrichment is also an important step in the civil nuclear fuel cycle, in producing low enriched uranium (LEU) for use as fuel for nuclear reactors to generate electricity. However, the same equipment used to produce LEU for nuclear reactor fuel can also be used to produce HEU for weapons. Safeguards at an enrichment plant are the array of assurances and verification techniques that ensure uranium is not diverted or enriched to HEU. There are several techniques for enriching uranium. The two most prevalent are gaseous diffusion, which uses older technology and requires a lot of energy, and gas centrifuge separation, which uses more advanced technology and is more energy efficient. Gaseous diffusion plants (GDPs) provide about 40% of current world enrichment capacity but are being phased out as newer gas centrifuge enrichment plants (GCEPs) are constructed. Estimates of current and future enrichment capacity are always approximate, due to the constant upgrades, expansions, and shutdowns occurring at enrichment plants, largely determined by economic interests. Currently, the world enrichment capacity is approximately 56 million kilogram separative work units (SWU) per year, with 22.5 million in gaseous diffusion and more than 33 million in gas centrifuge plants. Another 34 million SWU/year of capacity is under construction or planned for the near future, almost entirely using gas centrifuge separation. Other less-efficient techniques have also been used in the past, including electromagnetic and aerodynamic separations, but these are considered obsolete, at least from a commercial perspective. Laser isotope separation shows promise as a possible enrichment technique of the future but has yet to be

  17. Ion species stratification within strong shocks in two-ion plasmas

    Science.gov (United States)

    Keenan, Brett D.; Simakov, Andrei N.; Taitano, William T.; Chacón, Luis

    2018-03-01

    Strong collisional shocks in multi-ion plasmas are featured in many environments, with Inertial Confinement Fusion (ICF) experiments being one prominent example. Recent work [Keenan et al., Phys. Rev. E 96, 053203 (2017)] answered in detail a number of outstanding questions concerning the kinetic structure of steady-state, planar plasma shocks, e.g., the shock width scaling by the Mach number, M. However, it did not discuss shock-driven ion-species stratification (e.g., relative concentration modification and temperature separation). These are important effects since many recent ICF experiments have evaded explanation by standard, single-fluid, radiation-hydrodynamic (rad-hydro) numerical simulations, and shock-driven fuel stratification likely contributes to this discrepancy. Employing the state-of-the-art Vlasov-Fokker-Planck code, iFP, along with multi-ion hydro simulations and semi-analytics, we quantify the ion stratification by planar shocks with the arbitrary Mach number and the relative species concentration for two-ion plasmas in terms of ion mass and charge ratios. In particular, for strong shocks, we find that the structure of the ion temperature separation has a nearly universal character across ion mass and charge ratios. Additionally, we find that the shock fronts are enriched with the lighter ion species and the enrichment scales as M4 for M ≫ 1.

  18. A Systematic Approach to Marital Enrichment.

    Science.gov (United States)

    Dinkmeyer, Don; Carlson, Jon

    1986-01-01

    Presents a systematic approach to enriching marital relationships. The history and current status of marital enrichment is reviewed. An Adlerian approach to marital enrichment is described. Applications of the program in enrichment groups, marriage therapy and couple groups are included. (Author)

  19. 77 FR 13367 - General Electric-Hitachi Global Laser Enrichment, LLC, Proposed Laser-Based Uranium Enrichment...

    Science.gov (United States)

    2012-03-06

    ... NUCLEAR REGULATORY COMMISSION [NRC-2009-0157] General Electric-Hitachi Global Laser Enrichment, LLC, Proposed Laser-Based Uranium Enrichment Facility, Wilmington, NC AGENCY: Nuclear Regulatory... Impact Statement (EIS) for the proposed General Electric- Hitachi Global Laser Enrichment, LLC (GLE...

  20. The enrichment secondary market

    International Nuclear Information System (INIS)

    Einbund, D.R.

    1986-01-01

    This paper will addresses two topics: the background to the present status of the enrichment secondary market and the future outlook of the secondary market in enrichment services, and the viability of the nuclear fuel brokerage industry. These two topics are inevitably connected, as most secondary market activity, not only in enrichment but also in natural uranium, has traditionally been conducted with the participation of brokers. Therefore, the author interrelates these topics

  1. Thermal breeder fuel enrichment zoning

    International Nuclear Information System (INIS)

    Capossela, H.J.; Dwyer, J.R.; Luce, R.G.; McCoy, D.F.; Merriman, F.C.

    1992-01-01

    A method and apparatus for improving the performance of a thermal breeder reactor having regions of higher than average moderator concentration are disclosed. The fuel modules of the reactor core contain at least two different types of fuel elements, a high enrichment fuel element and a low enrichment fuel element. The two types of fuel elements are arranged in the fuel module with the low enrichment fuel elements located between the high moderator regions and the high enrichment fuel elements. Preferably, shim rods made of a fertile material are provided in selective regions for controlling the reactivity of the reactor by movement of the shim rods into and out of the reactor core. The moderation of neutrons adjacent the high enrichment fuel elements is preferably minimized as by reducing the spacing of the high enrichment fuel elements and/or using a moderator having a reduced moderating effect. 1 figure

  2. Uranium enrichment in the United States

    International Nuclear Information System (INIS)

    Hill, J.H.; Parks, J.W.

    1975-01-01

    History, improvement programs, status of electrical power availability, demands for uranium enrichment, operating plan for the U. S. enriching facilities, working inventory of enriched uranium, possible factors affecting deviations in the operating plan, status of gaseous diffusion technology, status of U. S. gas centrifuge advances, transfer of enrichment technology, gaseous diffusion--gas centrifuge comparison, new enrichment capacity, U. S. separative work pricing, and investment in nuclear energy are discussed. (LK)

  3. Ultrahigh thermal conductivity of isotopically enriched silicon

    Science.gov (United States)

    Inyushkin, Alexander V.; Taldenkov, Alexander N.; Ager, Joel W.; Haller, Eugene E.; Riemann, Helge; Abrosimov, Nikolay V.; Pohl, Hans-Joachim; Becker, Peter

    2018-03-01

    Most of the stable elements have two and more stable isotopes. The physical properties of materials composed of such elements depend on the isotopic abundance to some extent. A remarkably strong isotope effect is observed in the phonon thermal conductivity, the principal mechanism of heat conduction in nonmetallic crystals. An isotopic disorder due to random distribution of the isotopes in the crystal lattice sites results in a rather strong phonon scattering and, consequently, in a reduction of thermal conductivity. In this paper, we present new results of accurate and precise measurements of thermal conductivity κ(T) for silicon single crystals having three different isotopic compositions at temperatures T from 2.4 to 420 K. The highly enriched crystal containing 99.995% of 28Si, which is one of the most perfect crystals ever synthesized, demonstrates a thermal conductivity of about 450 ± 10 W cm-1 K-1 at 24 K, the highest measured value among bulk dielectrics, which is ten times greater than the one for its counterpart natSi with the natural isotopic constitution. For highly enriched crystal 28Si and crystal natSi, the measurements were performed for two orientations [001] and [011], a magnitude of the phonon focusing effect on thermal conductivity was determined accurately at low temperatures. The anisotropy of thermal conductivity disappears above 31 K. The influence of the boundary scattering on thermal conductivity persists sizable up to much higher temperatures (˜80 K). The κ(T) measured in this work gives the most accurate approximation of the intrinsic thermal conductivity of single crystal silicon which is determined solely by the anharmonic phonon processes and diffusive boundary scattering over a wide temperature range.

  4. Rheology, fatty acid profile and quality characteristics of nutrient enriched pizza base.

    Science.gov (United States)

    Gupta, Chaitali Sen; Milind; Jeyarani, T; Rajiv, Jyotsna

    2015-05-01

    Enrichment of thick bread type pizza base (PZB) was done by substituting wheat flour (WF) with 5, 10 and 15 % soya protein isolate (SPI). The rheological characteristics of WF showed that water absorption increased, extensibility and peak viscosity decreased when level of SPI increased from 5 to 15 %. Baking studies showed that spread ratio decreased and hardness values of PZB increased with the increase in amount of SPI from 5 to15 %. Beyond 10 % SPI, the overall quality of PZB was adversely affected. To the optimal blend of 10 % SPI, 5 % psyllium husk (PH) was added and the hydrogenated fat was replaced by canola oil (CAN) in enriched PZB. The enriched PZB treated with combination of additives had 1.7 and 1.6 times more protein and dietary fiber than the control PZB. Fatty acid analysis showed that the enriched PZB had 58.65 % oleic, 6.58 % linolenic acid and 31.28 % polyunsaturated fatty acid and no Trans fat was present.

  5. Enrichment into the 21st century

    International Nuclear Information System (INIS)

    Rutkowski, E.

    1995-01-01

    This article discusses the future of the enrichment services market into the next century. It is estimated that demand for enrichment services will reach 31 million SWU by the end of the century and remain constant for the following 10 years. The current world enrichment capacity is 44 million SWU, or some 50% ahead of the demand. This oversupply is projected to continue into the next century, but in spite of this, several suppliers are planning new enrichment facilities. HEU as a source of enriched uranium is examined. Overall, long-term prices for enrichment services are expected to decline in the coming decade

  6. The commercial role for centrifuge enrichment

    International Nuclear Information System (INIS)

    Readle, P.H.; Wilcox, P.

    1987-01-01

    The enrichment market is extremely competitive and capacity greatly exceeds demand. BNFL [British Nuclear Fuels Ltd.] is in a unique position in having commercial experience of the two enrichment technologies currently used industrially: diffusion, and centrifuge enrichment through its associate company Urenco. In addition, BNFL is developing laser enrichment techniques as part of a UK development programme. The paper describes the enrichment market, briefly discusses the relative merits of the various methods of uranium enrichment and concludes that the gas centrifuge will be best able to respond to market needs for at least the remainder of the century. (author)

  7. High enrichment to low enrichment core's conversion. Accidents analysis

    International Nuclear Information System (INIS)

    Abbate, P.; Rubio, R.; Doval, A.; Lovotti, O.

    1990-01-01

    This work analyzes the different accidents that may occur in the reactor's facility after the 20% high-enriched uranium core's conversion. The reactor (of 5 thermal Mw), built in the 50's and 60's, is of the 'swimming pool' type, with light water and fuel elements of the curve plates MTR type, enriched at 93.15 %. This analysis includes: a) accidents by reactivity insertion; b) accidents by coolant loss; c) analysis by flow loss and d) fission products release. (Author) [es

  8. Environmental Enrichment Effect on Fecal Glucocorticoid Metabolites and Captive Maned Wolf (Chrysocyon brachyurus) Behavior.

    Science.gov (United States)

    Coelho, Carlyle Mendes; de Azevedo, Cristiano Schetini; Guimarães, Marcelo Alcino de Barros Vaz; Young, Robert John

    2016-01-01

    Environmental enrichment is a technique that may reduce the stress of nonhuman animals in captivity. Stress may interfere with normal behavioral expression and affect cognitive decision making. Noninvasive hormonal studies can provide important information about the stress statuses of animals. This study evaluated the effectiveness of different environmental enrichment treatments in the diminution of fecal glucocorticoid metabolites (stress indicators) of three captive maned wolves (Chrysocyon brachyurus). Correlations of the fecal glucocorticoid metabolite levels with expressed behaviors were also determined. Results showed that environmental enrichment reduced fecal glucocorticoid metabolite levels. Furthermore, interspecific and foraging enrichment items were most effective in reducing stress in two of the three wolves. No definite pattern was found between behavioral and physiological responses to stress. In conclusion, these behavioral and physiological data showed that maned wolves responded positively from an animal well being perspective to the enrichment items presented.

  9. Pengaruh Job Enrichment terhadap Employee Engagement melalui Psychological Meaningfulness sebagai Mediator

    OpenAIRE

    Sungkit, Flavia Norpina; Meiyanto, IJK Sito

    2015-01-01

    The purpose of the study is to investigate the influence of job enrichment toward employee engagement through psychological meaningfulness as the mediator. Research design used is a cross-sectional study of 112 employees. Data is analyzed by multiple linear regression analysis. Result shows job enrichment is able to influence employee engagement significantly through psychological meaningfulness as the mediator. The p=0,000 with significance level 0,05. The sig F change shows 0,006, which is

  10. NAA analysis of enriched Zn-68 by

    International Nuclear Information System (INIS)

    Rafii, H.; Mirzaei, M.; Mirzajani, N.; Sardari, D.; Shahabi, I.; Majedi, F.

    2002-01-01

    Excessive application of enriched isotopes in various fields of sciences and industry necessitates measuring their abundant by a precise and rapid methos. Beside the inductively coupled plasma mass spectrometry, the thermal neutron activation analysis, NAA, is an alternative method, which is capable to determine trace amounts of elements as well as the elemental abundance. In this article the enrichment of Zn-68 in two different samples has been studied by mean of NAA. One sample was separated by an electromagnetic system in our center and the other was purchased from a French company, Cortecnet. The neutron irradiation was took place in MNSR reactor by flux 10 1 1n/cm 2 sec. for 30 min. and the produced radioactivity from Zn-69 m was measured one day after irradiation by HPGe detector. The results shows a good agreement with the reported ones and its low derivation of about ±3.05 indicates that the NAA is a precise, rapid, and supplemental method for analyzing enriched Zn-68

  11. Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers.

    Science.gov (United States)

    Kumar, Ashok A; Lim, Caeul; Moreno, Yovany; Mace, Charles R; Syed, Abeer; Van Tyne, Daria; Wirth, Dyann F; Duraisingh, Manoj T; Whitesides, George M

    2015-01-01

    This paper demonstrates the enrichment of reticulocytes by centrifuging whole blood through aqueous multiphase systems (AMPSs)-immiscible phases of solutions of polymers that form step-gradients in density. The interfaces of an AMPS concentrate cells; this concentration facilitates the extraction of blood enriched for reticulocytes. AMPS enrich reticulocytes from blood from both healthy and hemochromatosis donors. Varying the osmolality and density of the phases of AMPS provides different levels of enrichment and yield of reticulocytes. A maximum enrichment of reticulocytemia of 64 ± 3% was obtained from donors with hemochromatosis. When used on peripheral blood from normal donors, AMPS can provide a higher yield of enriched reticulocytes and a higher proportion of reticulocytes expressing CD71 than differential centrifugation followed by centrifugation over Percoll. Blood enriched for reticulocytes by AMPS could be useful for research on malaria. Several species of malaria parasites show a preference to invade young erythrocytes and reticulocytes; this preference complicates in vitro cultivation of these species in human blood. Plasmodium knowlesi malaria parasites invade normal human blood enriched for reticulocytes by AMPSs at a rate 2.2 times greater (P blood. Parasite invasion in normal blood enriched by AMPS was 1.8 times greater (P blood enriched to a similar reticulocytemia by differential centrifugation followed by centrifugation over Percoll. The enrichment of reticulocytes that are invaded by malaria parasites demonstrates that AMPSs can provide a label-free method to enrich cells for biological research. © 2014 Wiley Periodicals, Inc.

  12. Advanced Neutron Source enrichment study

    International Nuclear Information System (INIS)

    Bari, R.A.; Ludewig, H.; Weeks, J.R.

    1996-01-01

    A study has been performed of the impact on performance of using low-enriched uranium (20% 235 U) or medium-enriched uranium (35% 235 U) as an alternative fuel for the Advanced Neutron Source, which was initially designed to use uranium enriched to 93% 235 U. Higher fuel densities and larger volume cores were evaluated at the lower enrichments in terms of impact on neutron flux, safety, safeguards, technical feasibility, and cost. The feasibility of fabricating uranium silicide fuel at increasing material density was specifically addressed by a panel of international experts on research reactor fuels. The most viable alternative designs for the reactor at lower enrichments were identified and discussed. Several sensitivity analyses were performed to gain an understanding of the performance of the reactor at parametric values of power, fuel density, core volume, and enrichment that were interpolations between the boundary values imposed on the study or extrapolations from known technology

  13. Factors that predict consumer acceptance of enriched processed meats.

    Science.gov (United States)

    Shan, Liran C; Henchion, Maeve; De Brún, Aoife; Murrin, Celine; Wall, Patrick G; Monahan, Frank J

    2017-11-01

    The study aimed to understand predictors of consumers' purchase intention towards processed meat based functional foods (i.e. enriched processed meat). A cross-sectional survey was conducted with 486 processed meat consumers in spring 2016. Results showed that processed meats were perceived differently in healthiness, with sausage-type products perceived less healthy than cured meat products. Consumers were in general more uncertain than positive about enriched processed meat but differences existed in terms of the attitudes and purchase intention. Following regression analysis, consumers' purchase intention towards enriched processed meat was primarily driven by their attitudes towards the product concept. Perceived healthiness of existing products and eating frequency of processed meat were also positively associated with the purchase intention. Other factors such as general food choice motives, socio-demographic characteristics, consumer health and the consumption of functional foods and dietary supplements in general, were not significant predictors of the purchase intention for enriched processed meat. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Prospects and problems of uranium enrichment

    International Nuclear Information System (INIS)

    Imai, Ryukichi

    1974-01-01

    The problem of uranium enrichment now concerns principally peaceful nuclear power generation. With the current oil crisis, energy resources assume unprecedented importance. However, the requirements for enriched uranium vary with the vicissitude of the world situation in nuclear power generation; the enterprise of uranium enrichment is related to economic aspect. The following matters are described: dimension of enrichment problem, political factors, changes in requirements, projects in each country, and strategy of enrichment in Japan. (Mori, K.)

  15. Effects of exercise and enrichment on behaviour in CD-1 mice.

    Science.gov (United States)

    Aujnarain, Amiirah B; Luo, Owen D; Taylor, Natalie; Lai, Jonathan K Y; Foster, Jane A

    2018-04-16

    A host of scholarly work has characterized the positive effects of exercise and environmental enrichment on behaviour and cognition in animal studies. The purpose of this study was to investigate the uptake and longitudinal impact of exercise and enrichment on the behavioural phenotype of male and female CD-1 mice. CD-1 mice housed in standard (STD) or exercise and enrichment (EE) conditions post-weaning were tested in the 3-chamber sociability test, open field, and elevated plus maze and exercise activity was monitored throughout the enrichment protocol. Male and female EE mice both showed reduced anxiety and activity in the open field and elevated plus maze relative to sex-matched STD mice. EE altered social behaviours in a sex-specific fashion, with only female EE mice showing increased social preference relative to female STD mice and a preference for social novelty only present in male EE mice. This sexual dimorphism was not observed to be a product of exercise uptake, as CD-1 mice of both sexes demonstrated a consistent trend of wheel rotation frequencies. These findings suggest the importance of considering variables such as sex and strain on experimental design variables in future work on environmental enrichment. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Uranium enrichment: an overview

    International Nuclear Information System (INIS)

    Cazalet, J.

    1995-01-01

    This paper is a general presentation of uranium enrichment processes and assessments of the prevailing commercial and industrial situations. It gives first some theoretical aspects of enrichment in general and explains the differences between statistical and selective processes in particular. Then a review of the different processes is made with a comparison between them. Finally, some general remarks concerning applications are given and the risks of proliferation related to enrichment are mentioned. (J.S.). 4 refs., 5 figs., 8 tabs

  17. Slightly enriched uranium fuel for a PHWR

    International Nuclear Information System (INIS)

    Notari, C.; Marajofsky, A.

    1997-01-01

    An improved fuel element design for a PHWR using slightly enriched uranium fuel is presented. It maintains the general geometric disposition of the currently used in the argentine NPP's reactors, replacing the outer ring of rods by rods containing annular pellets. Power density reduction is achieved with modest burnup losses and the void volume in the pellets can be used to balance these two opposite effects. The results show that with this new design, the fuel can be operated at higher powers without violating thermohydraulic limits and this means an improvement in fuel management flexibility, particularly in the transition from natural uranium to slightly enriched uranium cycle. (author)

  18. Supply of low enriched (LEU) and highly enriched uranium (HEU) for research reactors

    International Nuclear Information System (INIS)

    Mueller, H.

    1997-01-01

    Enriched uranium for research reactors in the form of LEU /= low enriched uranium at 19.75% U-235) and HEU (= highly enriched uranium at 90 to 93% U-235) was and is - due to its high U-235 enrichment - a political fuel other than enriched uranium for power reactors. The sufficient availability of LEU and HEU is a vital question for research reactors, especially in Europe, in order to perform their peaceful research reactor programs. In the past the USA were in the Western hemisphere sole supplier of LEU and HEU. Today the USA have de facto stopped the supply of LEU and HEU, for HEU mainly due to political reasons. This paper deals, among others, with the present availability of LEU and HEU for European research reactors and touches the following topics: - historical US supplies, - influence of the RERTR-program, - characteristics of LEU and HEU, - military HEU enters the civil market, -what is the supply situation for LEU and HEU today? - outlook for safe supplies of LEU and HEU. (author)

  19. Development of an On-Line Uranium Enrichment Monitor

    International Nuclear Information System (INIS)

    Xuesheng, L.; Guorong, L.; Yonggang, Z.; Xueyuan, H. X.-Y.

    2015-01-01

    An on-line enrichment monitor was developed to measure the enrichment of UF6 flowing through the processing pipes in centrifuge uranium enrichment plant. A NaI(Tl) detector was used to measure the count rates of the 186 keV gamma ray emitted from 235U, and the total quantity of uranium was determined from thermodynamic characteristics of gaseous uranium hexafluoride. The results show that the maximum relative standard deviation is less than 1% when the measurement time is 120 s or more and the pressure is more than 2 kPa in the measurement chamber. There are two working models for the monitor. The monitor works normally in the continuous model, When the gas's pressure in the pipe fluctuates greatly, it can work in the intermittent model, and the measurement result is very well. The background of the monitor can be measured automatically periodically. It can control automatically electromagnetic valves open and close, so as to change the gas's quantity in the chamber. It is a kind of unattended and remote monitor, all of data can be transfer to central control room. It should be effective for nuclear materials accountability verifications and materials balance verification at uranium enrichment plant by using the monitor to monitor Uranium enrichment of gaseous uranium hexafluoride in the output end of cascade continuously. (author)

  20. Difference in physiological responses of growth, photosynthesis and calcification of the coccolithophore Emiliania huxleyi to acidification by acid and CO2 enrichment.

    Science.gov (United States)

    Fukuda, Shin-Ya; Suzuki, Yurina; Shiraiwa, Yoshihiro

    2014-09-01

    Ocean acidification, one of the great global environmental issues at present, is expected to result in serious damage on marine calcareous organisms such as corals and calcifying algae, which potentially release huge amounts of CO2 from the ocean to the atmosphere. The coccolithophore, Emiliania huxleyi (Haptophyceae), which frequently produces blooms, has greatly contributed to the biological CO2 pump. This study was aimed at analyzing effects of how E. huxleyi responds to acidification. Acidification was performed by two methods, namely by just adding HCl under bubbling ordinary air at 8.2-8.4, 7.6-7.8 and 7.1-7.3 (acidification by HCl) and by bubbling with ordinary air or with increased CO2 concentration such as 406, 816 and 1,192 ppm that maintained pH of the medium at 8.0-8.3, 7.6-7.9 and 7.5-7.7 (acidification by CO2 enrichment). As a result, cell growth and cellular calcification of E. huxleyi were strongly damaged by acidification by HCl, but not by acidification by CO2 enrichment. The activities of photosystems such as F v/F m and ϕPSII were not affected by any acidification conditions while photosynthetic O2 evolution was slightly stimulated. A (45)Ca-radiotracer experiment revealed that Ca(2+)-uptake was strongly suppressed by acidification with HCl. This suppression recovered after increasing the dissolved inorganic carbon (DIC) concentration and further stimulated by an additional increase in DIC concentration. The production of storage and coccolith polysaccharides was increased by acidification by HCl and also highly stimulated by acidification with CO2 enrichment. The present study clearly showed that the coccolithophore, E. huxleyi, has an ability to respond positively to acidification with CO2 enrichment, but not just acidification.

  1. RNA-Dependent Intergenerational Inheritance of Enhanced Synaptic Plasticity after Environmental Enrichment

    Directory of Open Access Journals (Sweden)

    Eva Benito

    2018-04-01

    Full Text Available Summary: Physical exercise in combination with cognitive training is known to enhance synaptic plasticity, learning, and memory and lower the risk for various complex diseases including Alzheimer’s disease. Here, we show that exposure of adult male mice to an environmental enrichment paradigm leads to enhancement of synaptic plasticity and cognition also in the next generation. We show that this effect is mediated through sperm RNA and especially miRs 212/132. In conclusion, our study reports intergenerational inheritance of an acquired cognitive benefit and points to specific miRs as candidates mechanistically involved in this type of transmission. : Environmental enrichment (EE, a combination of physical and mental exercise, has been shown to increase cognitive abilities in mice and in humans. Benito et al. find that offspring of male mice subjected to EE also show this increase. This effect is dependent on sperm RNA and involves microRNA212/132. Keywords: epigenetics, brain, microRNA, memory, intergenerational, transgenerational, exercise, environmental enrichment, cognition

  2. Recommendations based on semantically enriched museum collections

    NARCIS (Netherlands)

    Wang, Y.; Stash, N.; Aroyo, L.M.; Gorgels, P.; Rutledge, L.W.; Schreiber, G.

    2008-01-01

    This article presents the CHIP demonstrator1 for providing personalized access to digital museum collections. It consists of three main components: Art Recommender, Tour Wizard, and Mobile Tour Guide. Based on the semantically enriched Rijksmuseum Amsterdam2 collection, we show how Semantic Web

  3. The competitive enrichment market

    International Nuclear Information System (INIS)

    Parks, J.W.; Huffman, F.C.

    1984-01-01

    With the enactment of the ''Private Ownership of Special Nuclear Materials Act'' in 1964, the U.S. Government made provisions to enter into the uranium enrichment services business. Since nuclear power was in its infancy and the Government was promoting its growth as well as trying to help U.S. industry sell reactors overseas, the initial contracts (Requirements Contracts) for enrichment services placed most of the risks associated with the supplying of the services on the Government. Projections of nuclear power additions continued to grow and in 1972 the Atomic Energy Commission (AEC) stopped contracting under Requirements Contracts in order to study which mode of contracting best suited the commercial development of the industry. In mid-1973, the AEC introduced the Long-Term Fixed Commitment (LTFC) contract which shifted the risk to the customer. By mid-1974, AEC had contracts which completely used the enrichment capacity of its complex and refused to accept requests for additional contracts. This action further convinced European nations that they should continue to develop their own enrichment capacity and resulted in the EURODIF and URENCO projects. Before this time the U.S. supplied 100% of the world market for enriching services

  4. Enrichment: Dealing with overcapacity

    International Nuclear Information System (INIS)

    Peterson, C.H.

    1989-01-01

    Today's surplus of enrichment capacity will continue until at least the end of this century. This will challenge the ingenuity of the separative work unit (SWU) suppliers as they attempt to keep market share and remain profitable in a very competitive marketplace. The utilities will be faced with attractive choices, but making the best choice will require careful analysis and increased attention to market factors. Current demand projections will probably prove too high to the extent that more reactors are canceled or delayed. The DOE has the vast majority of the unused capacity, so it will feel the most immediate impact of this large surplus in productive capacity. The DOE has responded to these market challenges by planning another reorganization of its enriching operations. Without a major agreement among the governments affected by the current surplus in enrichment capacity, the future will see lower prices, more competitive terms, and the gradual substitution of centrifuge or laser enrichment for the gaseous diffusion plants. The competition that is forcing the gaseous diffusion prices down to marginal cost will provide the long-term price basis for the enrichment industry

  5. Comparing Multi-Step IMAC and Multi-Step TiO2 Methods for Phosphopeptide Enrichment

    Science.gov (United States)

    Yue, Xiaoshan; Schunter, Alissa; Hummon, Amanda B.

    2016-01-01

    Phosphopeptide enrichment from complicated peptide mixtures is an essential step for mass spectrometry-based phosphoproteomic studies to reduce sample complexity and ionization suppression effects. Typical methods for enriching phosphopeptides include immobilized metal affinity chromatography (IMAC) or titanium dioxide (TiO2) beads, which have selective affinity and can interact with phosphopeptides. In this study, the IMAC enrichment method was compared with the TiO2 enrichment method, using a multi-step enrichment strategy from whole cell lysate, to evaluate their abilities to enrich for different types of phosphopeptides. The peptide-to-beads ratios were optimized for both IMAC and TiO2 beads. Both IMAC and TiO2 enrichments were performed for three rounds to enable the maximum extraction of phosphopeptides from the whole cell lysates. The phosphopeptides that are unique to IMAC enrichment, unique to TiO2 enrichment, and identified with both IMAC and TiO2 enrichment were analyzed for their characteristics. Both IMAC and TiO2 enriched similar amounts of phosphopeptides with comparable enrichment efficiency. However, phosphopeptides that are unique to IMAC enrichment showed a higher percentage of multi-phosphopeptides, as well as a higher percentage of longer, basic, and hydrophilic phosphopeptides. Also, the IMAC and TiO2 procedures clearly enriched phosphopeptides with different motifs. Finally, further enriching with two rounds of TiO2 from the supernatant after IMAC enrichment, or further enriching with two rounds of IMAC from the supernatant TiO2 enrichment does not fully recover the phosphopeptides that are not identified with the corresponding multi-step enrichment. PMID:26237447

  6. The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells

    Energy Technology Data Exchange (ETDEWEB)

    Abbasi, Rashda [Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg (Germany); Efferth, Thomas [Institute of Pharmacy und Biochemistry, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz (Germany); Kuhmann, Christine [Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg (Germany); Opatz, Till [Institute of Organic Chemistry, Johannes Gutenberg University, Duesbergweg 10-14, 55128 Mainz (Germany); Hao, Xiaojiang [Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204 (China); Popanda, Odilia, E-mail: o.popanda@dkfz.de [Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg (Germany); Schmezer, Peter [Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg (Germany)

    2012-03-15

    Targeting synthetic lethality in DNA repair pathways has become a promising anti-cancer strategy. However little is known about such interactions with regard to the nucleotide excision repair (NER) pathway. Therefore, cell lines with a defect in the NER genes ERCC6 or XPC and their normal counterparts were screened with 53 chemically defined phytochemicals isolated from plants used in traditional Chinese medicine for differential cytotoxic effects. The screening revealed 12 drugs that killed NER-deficient cells more efficiently than proficient cells. Five drugs were further analyzed for IC{sub 50} values, effects on cell cycle distribution, and induction of DNA damage. Ascaridol was the most effective compound with a difference of > 1000-fold in resistance between normal and NER-deficient cells (IC{sub 50} values for cells with deficiency in ERCC6: 0.15 μM, XPC: 0.18 μM, and normal cells: > 180 μM). NER-deficiency combined with ascaridol treatment led to G2/M-phase arrest, an increased percentage of subG1 cells, and a substantially higher DNA damage induction. These results were confirmed in a second set of NER-deficient and -proficient cell lines with isogenic background. Finally, ascaridol was characterized for its ability to generate oxidative DNA damage. The drug led to a dose-dependent increase in intracellular levels of reactive oxygen species at cytotoxic concentrations, but only NER-deficient cells showed a strongly induced amount of 8-oxodG sites. In summary, ascaridol is a cytotoxic and DNA-damaging compound which generates intracellular reactive oxidative intermediates and which selectively affects NER-deficient cells. This could provide a new therapeutic option to treat cancer cells with mutations in NER genes. -- Highlights: ► Thousand-fold higher Ascaridol activity in NER-deficient versus proficient cells. ► Impaired repair of Ascaridol-induced oxidative DNA damage in NER-deficient cells. ► Selective activity of Ascaridol opens new therapy

  7. The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells

    International Nuclear Information System (INIS)

    Abbasi, Rashda; Efferth, Thomas; Kuhmann, Christine; Opatz, Till; Hao, Xiaojiang; Popanda, Odilia; Schmezer, Peter

    2012-01-01

    Targeting synthetic lethality in DNA repair pathways has become a promising anti-cancer strategy. However little is known about such interactions with regard to the nucleotide excision repair (NER) pathway. Therefore, cell lines with a defect in the NER genes ERCC6 or XPC and their normal counterparts were screened with 53 chemically defined phytochemicals isolated from plants used in traditional Chinese medicine for differential cytotoxic effects. The screening revealed 12 drugs that killed NER-deficient cells more efficiently than proficient cells. Five drugs were further analyzed for IC 50 values, effects on cell cycle distribution, and induction of DNA damage. Ascaridol was the most effective compound with a difference of > 1000-fold in resistance between normal and NER-deficient cells (IC 50 values for cells with deficiency in ERCC6: 0.15 μM, XPC: 0.18 μM, and normal cells: > 180 μM). NER-deficiency combined with ascaridol treatment led to G2/M-phase arrest, an increased percentage of subG1 cells, and a substantially higher DNA damage induction. These results were confirmed in a second set of NER-deficient and -proficient cell lines with isogenic background. Finally, ascaridol was characterized for its ability to generate oxidative DNA damage. The drug led to a dose-dependent increase in intracellular levels of reactive oxygen species at cytotoxic concentrations, but only NER-deficient cells showed a strongly induced amount of 8-oxodG sites. In summary, ascaridol is a cytotoxic and DNA-damaging compound which generates intracellular reactive oxidative intermediates and which selectively affects NER-deficient cells. This could provide a new therapeutic option to treat cancer cells with mutations in NER genes. -- Highlights: ► Thousand-fold higher Ascaridol activity in NER-deficient versus proficient cells. ► Impaired repair of Ascaridol-induced oxidative DNA damage in NER-deficient cells. ► Selective activity of Ascaridol opens new therapy options in

  8. Behavioral responses of three lemur species to different food enrichment devices.

    Science.gov (United States)

    Shapiro, Morgan E; Shapiro, Hannah G; Ehmke, Erin E

    2018-05-01

    Environmental enrichment is a tool used to promote the welfare and well-being of captive animals by encouraging the display of species-specific behaviors and reducing the stress or boredom induced by captive environments. Lemurs are highly endangered, yet few studies have analyzed the behavioral impacts of enrichment on captive populations. We studied the impacts of two novel enrichment devices on three lemur species (ring-tailed lemurs [Lemur catta], red-ruffed lemurs [Varecia rubra], and Coquerel's sifaka [Propithecus coquereli]) to determine both the overall and species-specific impacts of enrichment on lemur behavior. We recorded lemur behavior using the continuous sampling method to obtain behavior duration and analyzed our results using ANOVA Repeated Measures. Results showed enrichment effectiveness differed for each species and that different enrichment devices had varying impacts on lemur behavior across all species. We attributed the differences in species-specific responses to the unique locomotor patterns and methods of diet acquisition of each species, and the variances in behavioral responses across all species to the characteristics of each device. Our study highlights the importance of species-specific enrichment and encourages further research in this field in order to maximize the positive effects of enrichment, which in turn has the potential to affect the overall well-being of captive populations. © 2018 Wiley Periodicals, Inc.

  9. Determining method and device for enrichment distribution inside of fuel assembly

    International Nuclear Information System (INIS)

    Hirano, Yasushi; Hida, Kazuki; Sakurada, Koichi.

    1997-01-01

    An enrichment degree at an initial burning stage of each of fuel rods of a BWR type reactor assembly is divided into groups. The enrichment degree at the initial burning stage of each of the groups is inputted, and the burning period from the loading to the taking out is divided into a plurality of burning steps. Nuclear characteristics of fuel assemblies such as the power of fuel rods, R-factor and infinite multiplication factor in each of the burning steps are estimated. The enrichment degree of the group of enrichment degree at the initial burning stage and the estimated power of fuel rods in a reactor operation state during the burning step are stored in the memory. A sensitivity coefficient showing the amount of change of the power of fuel rods in the burning step relative to the change of the enrichment degree of the group of enrichment degree is evaluated. A weighing function in the burning step is inputted. The maximum value of the product of the weighing function and the power of fuel rods throughout the entire burning steps is determined as an aimed function. Optimization calculation is conducted for determining the enrichment degree of the group so as to minimize the aimed function thereby determining the distribution of the enrichment degree. (N.H.)

  10. Oxygen enrichment incineration

    International Nuclear Information System (INIS)

    Kim, Jeong Guk; Yang, Hee Chul; Park, Geun Il; Kim, Joon Hyung

    2000-10-01

    Oxygen enriched combustion technology has recently been used in waste incineration. To apply the oxygen enrichment on alpha-bearing waste incineration, which is being developed, a state-of-an-art review has been performed. The use of oxygen or oxygen-enriched air instead of air in incineration would result in increase of combustion efficiency and capacity, and reduction of off-gas product. Especially, the off-gas could be reduced below a quarter, which might reduce off-gas treatment facilities, and also increase an efficiency of off-gas treatment. However, the use of oxygen might also lead to local overheating and high nitrogen oxides (NOx) formation. To overcome these problems, an application of low NOx oxy-fuel burner and recycling of a part of off-gas to combustion chamber have been suggested

  11. Oxygen enrichment incineration

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jeong Guk; Yang, Hee Chul; Park, Geun Il; Kim, Joon Hyung

    2000-10-01

    Oxygen enriched combustion technology has recently been used in waste incineration. To apply the oxygen enrichment on alpha-bearing waste incineration, which is being developed, a state-of-an-art review has been performed. The use of oxygen or oxygen-enriched air instead of air in incineration would result in increase of combustion efficiency and capacity, and reduction of off-gas product. Especially, the off-gas could be reduced below a quarter, which might reduce off-gas treatment facilities, and also increase an efficiency of off-gas treatment. However, the use of oxygen might also lead to local overheating and high nitrogen oxides (NOx) formation. To overcome these problems, an application of low NOx oxy-fuel burner and recycling of a part of off-gas to combustion chamber have been suggested.

  12. Spectral analysis of the He-enriched sdO-star HD 127493

    Science.gov (United States)

    Dorsch, Matti; Latour, Marilyn; Heber, Ulrich

    2018-02-01

    The bright sdO star HD127493 is known to be of mixed H/He composition and excellent archival spectra covering both optical and ultraviolet ranges are available. UV spectra play a key role as they give access to many chemical species that do not show spectral lines in the optical, such as iron and nickel. This encouraged the quantitative spectral analysis of this prototypical mixed H/He composition sdO star. We determined atmospheric parameters for HD127493 in addition to the abundance of C, N, O, Si, S, Fe, and Ni in the atmosphere using non-LTE model atmospheres calculated with TLUSTY/SYNSPEC. A comparison between the parallax distance measured by Hipparcos and the derived spectroscopic distance indicate that the derived atmospheric parameters are realistic. From our metal abundance analysis, we find a strong CNO signature and enrichment in iron and nickel.

  13. A Multidimensional System for Phosphopeptide Analysis Using TiO{sub 2} Enrichment and Ion-exchange Chromatography with Mass Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Kun; Yoo, Jisun; Kim, Eunmin; Kim, Jin Young; Kim, Young Hwan; Yoo, Jong Shin [Korea Basic Science Institute, Ochang (Korea, Republic of); Oh, Han Bin [Sogang Univ., Seoul (Korea, Republic of)

    2012-10-15

    Although offline enrichment of phosphorylated peptides is widely used, enrichment for phosphopeptides using TiO{sub 2} is often performed manually, which is labor-intensive and can lead to irreproducible results. To address the problems associated with offline enrichment and to improve the effectiveness of phosphopeptide detection, we developed an automated online enrichment system for phosphopeptide analysis. A standard protein mixture comprising BSA, fetuin, crystalline, α-casein and β-casein, and ovalbumin was assessed using our new system. Our multidimensional system has four main parts: a sample pump, a 20-mm TiO{sub 2}-based column, a weak anion-exchange, and a strong cation-exchange (2:1 WAX:SCX) separation column with LC/MS. Phosphorylated peptides were successfully detected using the TiO{sub 2}-based online system with little interference from nonphosphorylated peptides. Our results confirmed that our online enrichment system is a simple and efficient method for detecting phosphorylated peptides.

  14. Transgenerational effects of mild heat in Arabidopsis thaliana show strong genotype specificity that is explained by climate at origin.

    Science.gov (United States)

    Groot, Maartje P; Kubisch, Alexander; Ouborg, N Joop; Pagel, Jörn; Schmid, Karl J; Vergeer, Philippine; Lampei, Christian

    2017-08-01

    Transgenerational environmental effects can trigger strong phenotypic variation. However, it is unclear how cues from different preceding generations interact. Also, little is known about the genetic variation for these life history traits. Here, we present the effects of grandparental and parental mild heat, and their combination, on four traits of the third-generation phenotype of 14 Arabidopsis thaliana genotypes. We tested for correlations of these effects with climate and constructed a conceptual model to identify the environmental conditions that favour the parental effect on flowering time. We observed strong evidence for genotype-specific transgenerational effects. On average, A. thaliana accustomed to mild heat produced more seeds after two generations. Parental effects overruled grandparental effects in all traits except reproductive biomass. Flowering was generally accelerated by all transgenerational effects. Notably, the parental effect triggered earliest flowering in genotypes adapted to dry summers. Accordingly, this parental effect was favoured in the model when early summer heat terminated the growing season and environments were correlated across generations. Our results suggest that A. thaliana can partly accustom to mild heat over two generations and genotype-specific parental effects show non-random evolutionary divergence across populations that may support climate change adaptation in the Mediterranean. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  15. Effects of CO(2) enrichment on photosynthesis, growth, and biochemical composition of seagrass Thalassia hemprichii (Ehrenb.) Aschers.

    Science.gov (United States)

    Jiang, Zhi Jian; Huang, Xiao-Pin; Zhang, Jing-Ping

    2010-10-01

    The effects of CO₂ enrichment on various ecophysiological parameters of tropical seagrass Thalassia hemprichii (Ehrenb.) Aschers were tested. T. hemprichii, collected from a seagrass bed in Xincun Bay, Hainan island of Southern China, was cultured at 4 CO₂ (aq) concentrations in flow-through seawater aquaria bubbled with CO₂ . CO₂ enrichment considerably enhanced the relative maximum electron transport rate (RETR(max) ) and minimum saturating irradiance (E(k) ) of T. hemprichii. Leaf growth rate of CO₂ -enriched plants was significantly higher than that in unenriched treatment. Nonstructural carbohydrates (NSC) of T. hemprichii, especially in belowground tissues, increased strongly with elevated CO₂ (aq), suggesting a translocation of photosynthate from aboveground to belowground tissues. Carbon content in belowground tissues showed a similar response with NSC, while in aboveground tissues, carbon content was not affected by CO₂ treatments. In contrast, with increasing CO₂ (aq), nitrogen content in aboveground tissues markedly decreased, but nitrogen content in belowground was nearly constant. Carbon: nitrogen ratio in both tissues were obviously enhanced by increasing CO₂ (aq). Thus, these results indicate that T. hemprichii may respond positively to CO₂ -induced acidification of the coastal ocean. Moreover, the CO₂ -stimulated improvement of photosynthesis and NSC content may partially offset negative effects of severe environmental disturbance such as underwater light reduction. © 2010 Institute of Botany, Chinese Academy of Sciences.

  16. 75 FR 10525 - In the Matter of: AREVA Enrichment Services, LLC (Eagle Rock Enrichment Facility) and All Other...

    Science.gov (United States)

    2010-03-08

    ...: AREVA Enrichment Services, LLC (Eagle Rock Enrichment Facility) and All Other Persons Who Seek or Obtain... for the Implementation of a Safeguards Information Program (Effective Immediately) I AREVA Enrichment... it to construct and operate a uranium enrichment facility in Bonneville County, Idaho. AES submitted...

  17. Mangrove microniches determine the structural and functional diversity of enriched petroleum hydrocarbon-degrading consortia.

    Science.gov (United States)

    Gomes, Newton C M; Flocco, Cecilia G; Costa, Rodrigo; Junca, Howard; Vilchez, Ramiro; Pieper, Dietmar H; Krögerrecklenfort, Ellen; Paranhos, Rodolfo; Mendonça-Hagler, Leda C S; Smalla, Kornelia

    2010-11-01

    In this study, the combination of culture enrichments and molecular tools was used to identify bacterial guilds, plasmids and functional genes potentially important in the process of petroleum hydrocarbon (PH) decontamination in mangrove microniches (rhizospheres and bulk sediment). In addition, we aimed to recover PH-degrading consortia (PHDC) for future use in remediation strategies. The PHDC were enriched with petroleum from rhizosphere and bulk sediment samples taken from a mangrove chronically polluted with oil hydrocarbons. Southern blot hybridization (SBH) assays of PCR amplicons from environmental DNA before enrichments resulted in weak positive signals for the functional gene types targeted, suggesting that PH-degrading genotypes and plasmids were in low abundance in the rhizosphere and bulk sediments. However, after enrichment, these genes were detected and strong microniche-dependent differences in the abundance and composition of hydrocarbonoclastic bacterial populations, plasmids (IncP-1α, IncP-1β, IncP-7 and IncP-9) and functional genes (naphthalene, extradiol and intradiol dioxygenases) were revealed by in-depth molecular analyses [PCR-denaturing gradient gel electrophoresis and hybridization (SBH and microarray)]. Our results suggest that, despite the low abundance of PH-degrading genes and plasmids in the environmental samples, the original bacterial composition of the mangrove microniches determined the structural and functional diversity of the PHDC enriched. © 2010 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  18. <strong>Genes Involved in Human Ribosome Biogenesis areTranscriptionally Upregulated in Colorectal Cancerstrong>

    DEFF Research Database (Denmark)

    Mansilla, Francisco; Lamy, Philippe; Ørntoft, Torben Falck

    2009-01-01

    Microarray gene expression profiling comprising 168 colorectal adenocarcinomas and 10 normal mucosas showed that over 79% of the genes involved in human ribosome biogenesis are significantly upregulated (log2>0.5, p<10-3) when compared to normal mucosa. Overexpression was independent of microsate......Microarray gene expression profiling comprising 168 colorectal adenocarcinomas and 10 normal mucosas showed that over 79% of the genes involved in human ribosome biogenesis are significantly upregulated (log2>0.5, p... of microsatellite status. The promoters of the genes studied showed a significant enrichment for several transcription factor binding sites. There was a significant correlation between the number of binding site targets for these transcription factors and the observed gene transcript upregulation. The upregulation...

  19. Criticality of mixtures of plutonium and high enriched uranium

    International Nuclear Information System (INIS)

    Grolleau, E.; Lein, M.; Leka, G.; Maidou, B.; Klenov, P.

    2003-01-01

    This paper presents a criticality evaluation of moderated homogeneous plutonium-uranium mixtures. The fissile media studied are homogeneous mixtures of plutonium and high enriched uranium in two chemical forms: aqueous mixtures of metal and mixtures of nitrate solutions. The enrichment of uranium considered are 93.2wt.% 235 U and 100wt.% 235 U. The 240 Pu content in plutonium varies from 0wt.% 240 Pu to 12wt.% 240 Pu. The critical parameters (radii and masses of a 20 cm water reflected sphere) are calculated with the French criticality safety package CRISTAL V0. The comparison of the calculated critical parameters as a function of the moderator-to-fuel atomic ratio shows significant ranges in which high enriched uranium systems, as well as plutonium-uranium mixtures, are more reactive than plutonium systems. (author)

  20. Recovery of the Decorin-Enriched Fraction, Extract (D, From Human Skin: An Accelerated Protocol

    Directory of Open Access Journals (Sweden)

    Denys N. Wheatley

    2004-01-01

    Full Text Available The original extraction procedure of Engel and Catchpole [1] has often been used to recover decorin-enriched material from the skin. This material has a strong inhibitory effect on fibroblast proliferation, and clearly suppresses it in skin except after the first 5–6 days of wounding when new scaffold material is required. The aim of our present study has been to find and evaluate the product of a faster recovery method, and to check its consistency as a more reliable means of regularly obtaining sufficient material for topical application in wounds that might become hypertrophic. Modifications of the original Toole and Lowther [2] extraction procedure have been carefully evaluated in an attempt to cut preparation time without compromising biological activity of the inhibitory extract. We have devised a faster recovery procedure without compromising biological activity, even if initial recovery has been somewhat reduced. The latter problem could be offset by repeated cycles of the final extraction step. The main inhibitory activity is shown to be within the decorin-enriched “extract D,” as the core protein and DSPG II. Adjustment of the extract towards neutrality after dialysis against water keeps most of the extracted protein in solution and yielded a decorin-enriched preparation that had a specific activity equivalent to that of the old method. It also yielded a fraction that was readily lyophilised to give a small amount of material that could be stored indefinitely without loss of activity and readily redissolved in aqueous solution. A reliable and relatively quick method is presented for the production, from human skin, of a decorin-enriched preparation that has strong fibroblast inhibitory action. The value of the procedure is that it is inexpensive and can produce the quantities that might be used topically in reducing hypertrophic scarring of wounds.

  1. 76 FR 387 - Atomic Safety and Licensing Board; AREVA Enrichment Services, LLC (Eagle Rock Enrichment Facility)

    Science.gov (United States)

    2011-01-04

    ... and Licensing Board; AREVA Enrichment Services, LLC (Eagle Rock Enrichment Facility) December 17, 2010... construction and operation of a gas centrifuge uranium enrichment facility--denoted as the Eagle Rock... site at http://www.nrc.gov/materials/fuel-cycle-fac/arevanc.html . These and other documents relating...

  2. Exposure to Enriched Environment Decreases Neurobehavioral Deficits Induced by Neonatal Glutamate Toxicity

    Directory of Open Access Journals (Sweden)

    Peter Kiss

    2013-09-01

    Full Text Available Environmental enrichment is a popular strategy to enhance motor and cognitive performance and to counteract the effects of various harmful stimuli. The protective effects of enriched environment have been shown in traumatic, ischemic and toxic nervous system lesions. Monosodium glutamate (MSG is a commonly used taste enhancer causing excitotoxic effects when given in newborn animals. We have previously demonstrated that MSG leads to a delay in neurobehavioral development, as shown by the delayed appearance of neurological reflexes and maturation of motor coordination. In the present study we aimed at investigating whether environmental enrichment is able to decrease the neurobehavioral delay caused by neonatal MSG treatment. Newborn pups were treated with MSG subcutaneously on postnatal days 1, 5 and 9. For environmental enrichment, we placed rats in larger cages, supplemented with different toys that were altered daily. Normal control and enriched control rats received saline treatment only. Physical parameters such as weight, day of eye opening, incisor eruption and ear unfolding were recorded. Animals were observed for appearance of reflexes such as negative geotaxis, righting reflexes, fore- and hindlimb grasp, fore- and hindlimb placing, sensory reflexes and gait. In cases of negative geotaxis, surface righting and gait, the time to perform the reflex was also recorded daily. For examining motor coordination, we performed grid walking, footfault, rope suspension, rota-rod, inclined board and walk initiation tests. We found that enriched environment alone did not lead to marked alterations in the course of development. On the other hand, MSG treatment caused a slight delay in reflex development and a pronounced delay in weight gain and motor coordination maturation. This delay in most signs and tests could be reversed by enriched environment: MSG-treated pups kept under enriched conditions showed no weight retardation, no reflex delay in

  3. The low-enrichment fuel development program

    International Nuclear Information System (INIS)

    Stahl, D.

    1993-01-01

    In the 1950s and 1960s, low-power research reactors were built around the world utilized MTR-type fuel elements containing 20% enriched uranium. However, the demand for higher specific power created a need for greater uranium-235 concentrations. Early difficulties in increasing uranium content led to the substitution of highly enriched uranium in place of the 20% enriched fuel previously utilized. The highly enriched material also yielded other benefits including longer core residence time, higher specific reactivity, and somewhat lower cost. Highly enriched material then became readily available and was used for high-power reactors as well as in low-power reactors where 20% enriched material would have sufficed. The trend toward higher and higher specific power also led to the development of the dispersion-type fuels which utilized highly enriched uranium at a concentration of about 40 wt%. In the 1970's, however, concerns were raised about the proliferation resistance of fuels and fuel cycles. As a consequence, the U.S. Department of State has recently prohibited the foreign shipment of highly enriched material, except where prior contractual obligation or special merit exists. This will impact on the availability and utilization of highly enriched uranium for research and test reactor fuel. It has also stimulated development programs on fuels with higher uranium content which would allow the use of uranium of lower enrichment. The purpose of this report is to briefly describe the overall fuel-development program which is coordinated by Argonne National Laboratory for the Department of Energy, and to indicate the current and potential uranium loadings. Other reports will address the individual fuel-development activities in greater detail

  4. Effects of CO2 Enrichment on Growth and Development of Impatiens hawkeri

    Science.gov (United States)

    Zhang, Fan-Fan; Wang, Yan-Li; Huang, Zhi-Zhe; Zhu, Xiao-Chen; Zhang, Feng-Jiao; Chen, Fa-Di; Fang, Wei-Min; Teng, Nian-Jun

    2012-01-01

    The effects of CO2 enrichment on growth and development of Impatiens hawkeri, an important greenhouse flower, were investigated for the purpose of providing scientific basis for CO2 enrichment to this species in greenhouse. The plants were grown in CO2-controlled growth chambers with 380 (the control) and 760 (CO2 enrichment) μmol·mol−1, respectively. The changes in morphology, physiology, biochemistry, and leaf ultrastructure of Impatiens were examined. Results showed that CO2 enrichment increased flower number and relative leaf area compared with the control. In addition, CO2 enrichment significantly enhanced photosynthetic rate, contents of soluble sugars and starch, activities of peroxidase (POD), superoxide dismutase (SOD), and ascorbate peroxidase (APX), but reduced chlorophyll content and malondialdehyde (MDA) content. Furthermore, significant changes in chloroplast ultrastructure were observed at CO2 enrichment: an increased number of starch grains with an expanded size, and an increased ratio of stroma thylakoid to grana thylakoid. These results suggest that CO2 enrichment had positive effects on Impatiens, that is, it can improve the visual value, promote growth and development, and enhance antioxidant capacity. PMID:22536147

  5. The ecological risk assessment of heavy metals in the Kuihe River basin (Xuzhou section) and the characteristics of plant enrichment

    Science.gov (United States)

    Sun, Ling; Zheng, Lei

    2018-01-01

    In order to investigate Kuihe River basin of heavy metals (As, Cd, Cr, Cu, Mn, Ni, Pb and Zn) pollution, the determination of the Kuihe River water body, the bottom of the river silt, riparian soil plants and heavy metal content of 9 kinds of riparian plants, investigate the pollution situation, so as to screen out the plants that has potential of enrichment and rehabilitation of heavy metal pollution. The results showed that Cd and Mn in the water body exceed bid; The pollution of Zn and Cu in the bottom mud is serious, potential ecological risk of heavy metals is Zn>Cu>Pb>Ni>Cd>As>Cr>Mn Riparian soil affected by sewage and overflow of sediment has significant positive correlation with soil heavy metals, among them, the Zn and Cu are heavy pollution; The selective absorption of heavy metals by 9 kinds of dominant plant leads to its bio concentration factor (BCF) of Cr and Pb on the low side, are all less than 1, from the translocation factor (TF), Setcreasea purpurea and Poa annua showed obvious roots type hoarding. Poa annua and Lycium chinense have a resistance on the absorption of heavy metals, Lythrum salicaria, Photinia serrulata and Broussonetia papyrifera have a unique advantage on enrichment of heavy metals, Broussonetia papyri era on a variety of strong ability of enrichment and transfer of heavy metals suggests that the woody plants in the vast application prospect in the field of rehabilitation technology of heavy metals.

  6. Effect of Se-enriched Organic Fertilizers on Selenium Accumulation in Corn and Soil

    Directory of Open Access Journals (Sweden)

    LI Sheng-nan

    2015-12-01

    Full Text Available The effect of two Se-enriched organic fertilizers (cow dung and rice straw biochar on selenium accumulation of corn growing in selenium deficient soil was studied with pot experiment. The results showed that corn accumulated more selenium and the selenium was much easier to convert from root to shoot in the corn plant with the application of Se-enriched cow dung than Se-enriched rice straw biochar. With the application of more organic fertilizer such as 25 t·hm-2 Se-enriched cow dung or 40 t·hm-2 Se-enriched rice straw biochar, the accumulation of selenium and growth status of corn were getting better than the other treatments. At the same time, as the application amount of Se-enriched organic fertilizers (cow dung and rice straw biochar increased, the total selenium content in the soil also increased, which positively correlated with each other.

  7. AEC determines uranium enrichment policy

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    The Advisory Committee on Uranium Enrichment of the Atomic Energy Commission (AEC) has submitted a report to AEC chairman concerning the promotion of the introduction of advanced material, high performance centrifuges to replace conventional metallic drum centrifuges, and the development of next generation advanced centrifuges. The report also called for the postponement until around 1997 of the decision whether the development should be continued or not on atomic vapor laser isotope separation (AVLIS) and molecular laser isotope separation (MLIS) processes, as well as the virtual freezing of the construction of a chemical process demonstration plant. The report was approved by the AEC chairman in August. The uranium enrichment service market in the world will continue to be characterized by oversupply. The domestic situation of uranium enrichment supply-demand trend, progress of the expansion of Rokkasho enrichment plant, the trend in the development of gas centrifuge process and the basic philosophy of commercializing domestic uranium enrichment are reported. (K.I.)

  8. Gaseous diffusion -- the enrichment workhorse

    International Nuclear Information System (INIS)

    Shoemaker, J.E. Jr.

    1984-01-01

    Construction of the first large-scale gaseous diffusion facility was started as part of the Manhattan Project in Oak Ridge, Tennessee, in 1943. This facility, code named ''K-25,'' began operation in January 1945 and was fully on stream by September 1945. Four additional process buildings were later added in Oak Ridge as the demand for enriched uranium escalated. New gaseous diffusion plants were constructed at Paducah, Kentucky, and Portsmouth, Ohio, during this period. The three gaseous diffusion plants were the ''workhorses'' which provided the entire enriched uranium demand for the United States during the 1950s and 1960s. As the demand for enriched uranium for military purposes decreased during the early 1960s, power to the diffusion plants was curtailed to reduce production. During the 1960s, as plans for the nuclear power industry were formulated, the role of the diffusion plants gradually changed from providing highly-enriched uranium for the military to providing low-enriched uranium for power reactors

  9. ToNER: A tool for identifying nucleotide enrichment signals in feature-enriched RNA-seq data.

    Directory of Open Access Journals (Sweden)

    Yuttachon Promworn

    Full Text Available Biochemical methods are available for enriching 5' ends of RNAs in prokaryotes, which are employed in the differential RNA-seq (dRNA-seq and the more recent Cappable-seq protocols. Computational methods are needed to locate RNA 5' ends from these data by statistical analysis of the enrichment. Although statistical-based analysis methods have been developed for dRNA-seq, they may not be suitable for Cappable-seq data. The more efficient enrichment method employed in Cappable-seq compared with dRNA-seq could affect data distribution and thus algorithm performance.We present Transformation of Nucleotide Enrichment Ratios (ToNER, a tool for statistical modeling of enrichment from RNA-seq data obtained from enriched and unenriched libraries. The tool calculates nucleotide enrichment scores and determines the global transformation for fitting to the normal distribution using the Box-Cox procedure. From the transformed distribution, sites of significant enrichment are identified. To increase power of detection, meta-analysis across experimental replicates is offered. We tested the tool on Cappable-seq and dRNA-seq data for identifying Escherichia coli transcript 5' ends and compared the results with those from the TSSAR tool, which is designed for analyzing dRNA-seq data. When combining results across Cappable-seq replicates, ToNER detects more known transcript 5' ends than TSSAR. In general, the transcript 5' ends detected by ToNER but not TSSAR occur in regions which cannot be locally modeled by TSSAR.ToNER uses a simple yet robust statistical modeling approach, which can be used for detecting RNA 5'ends from Cappable-seq data, in particular when combining information from experimental replicates. The ToNER tool could potentially be applied for analyzing other RNA-seq datasets in which enrichment for other structural features of RNA is employed. The program is freely available for download at ToNER webpage (http://www4a

  10. ToNER: A tool for identifying nucleotide enrichment signals in feature-enriched RNA-seq data.

    Science.gov (United States)

    Promworn, Yuttachon; Kaewprommal, Pavita; Shaw, Philip J; Intarapanich, Apichart; Tongsima, Sissades; Piriyapongsa, Jittima

    2017-01-01

    Biochemical methods are available for enriching 5' ends of RNAs in prokaryotes, which are employed in the differential RNA-seq (dRNA-seq) and the more recent Cappable-seq protocols. Computational methods are needed to locate RNA 5' ends from these data by statistical analysis of the enrichment. Although statistical-based analysis methods have been developed for dRNA-seq, they may not be suitable for Cappable-seq data. The more efficient enrichment method employed in Cappable-seq compared with dRNA-seq could affect data distribution and thus algorithm performance. We present Transformation of Nucleotide Enrichment Ratios (ToNER), a tool for statistical modeling of enrichment from RNA-seq data obtained from enriched and unenriched libraries. The tool calculates nucleotide enrichment scores and determines the global transformation for fitting to the normal distribution using the Box-Cox procedure. From the transformed distribution, sites of significant enrichment are identified. To increase power of detection, meta-analysis across experimental replicates is offered. We tested the tool on Cappable-seq and dRNA-seq data for identifying Escherichia coli transcript 5' ends and compared the results with those from the TSSAR tool, which is designed for analyzing dRNA-seq data. When combining results across Cappable-seq replicates, ToNER detects more known transcript 5' ends than TSSAR. In general, the transcript 5' ends detected by ToNER but not TSSAR occur in regions which cannot be locally modeled by TSSAR. ToNER uses a simple yet robust statistical modeling approach, which can be used for detecting RNA 5'ends from Cappable-seq data, in particular when combining information from experimental replicates. The ToNER tool could potentially be applied for analyzing other RNA-seq datasets in which enrichment for other structural features of RNA is employed. The program is freely available for download at ToNER webpage (http://www4a.biotec.or.th/GI/tools/toner) and Git

  11. Considering the post-1995 enrichment market

    International Nuclear Information System (INIS)

    Gunter, L.

    1994-01-01

    World demand for uranium enrichment services is likely to grow only a little over the next decade, from the current 28 million separative work units (SWU) per year to 33 MSWU per year. Much of the growth will come from Asia where nuclear generating capacity is still increasing. The current situation of the primary enrichment companies is summarized. The primary Western suppliers, Cogema, United States Enrichment Corporation and Urenco, are competing for increased market share in the USA, Europe and Asia as utilities purchase their post-1995 requirements. Entry of the Russian enrichment company, Tenex, into Western markets has been limited by trade restrictions. As a consequence of disarmament, blended weapons material has resulted in a surplus of low-enriched uranium. Together with over-capacity amongst the primary enrichers this has led to an expectation that reduced prices will be negotiable in the medium term. (3 figures). (UK)

  12. Proposal for Monitoring Within the Centrifuge Cascades of Uranium Enrichment Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Farrar, David R.

    2017-04-01

    Safeguards are technical measures implemented by the International Atomic Energy Agency (IAEA) to independently verify that nuclear material is not diverted from peaceful purposes to weapons (IAEA, 2017a). Safeguards implemented at uranium enrichment facilities (facilities hereafter) include enrichment monitors (IAEA, 2011). Figure 1 shows a diagram of how a facility could be monitored. The use of a system for monitoring within centrifuge cascades is proposed.

  13. Present state of development of uranium enrichment

    International Nuclear Information System (INIS)

    1979-01-01

    The pilot plant for uranium enrichment started the operation on September 12, 1979. The pilot plant has been constructed by the Power Reactor and Nuclear Fuel Development Corp. in Ningyo Pass, Okayama Prefecture. 7000 centrifugal separators will be installed by mid 1981, and yearly production of 70 t SWU is expected. The Uranium Enrichment Committee of Japan Atomic Industrial Forum has made the proposal on the method of forwarding the development of uranium enrichment in Japan to Atomic Energy Commission and related government offices in December, 1978. This survey summarized the trends of uranium enrichment in Japan and foreign countries and the problems about nuclear non-proliferation, and provides with the reference materials. The demand and supply of uranium enrichment in the world, the present states and plans in USA, Europe, USSR and others, the demand and supply of uranium enrichment and the measures for securing it in Japan, the present state and future plan of uranium enrichment project in Japan, the international regulation of uranium enrichment, the recent policy of USA and INFCE, and the trend of the regulation of utilizing enriched uranium are described. Moreover, the concept of separation works in uranium enrichment and the various technologies of separation are explained. (Kako, I.)

  14. Origin of enormous trace metal enrichments in weathering mantles of Jurassic carbonates: evidence from Sr, Nd and Pb isotopes

    Science.gov (United States)

    Hissler, C.; Stille, P.; Juilleret, J.; Iffly, J.; Perrone, T.; Morvan, G.

    2013-12-01

    ) and Cd (2.4ppm). The underlying limestone and marl show, compared to average world carbonates, enrichments in the same elements and trace element distribution patterns similar to the soil suggesting their close genetic relationship. Pb, Sr and Nd isotope data allow to identify three principal components in the soil: a silicate-rich phase at close to the surface, a strongly trace metal enriched component at the bottom of the soil profile and an anthropogenic, atmosphere- derived component detected in the soil leachates. The isotopic mixing curves defined by the soil samples point to the close genetic connection between upper and lowermost soil horizons. The Nd isotopic composition of the leachates of all soil horizons are in contrast to the untreated soil and residual soil samples very homogeneous suggesting that the leachable phases of the upper and lower soil horizons are genetically connected. The downward migration of the trace metals is stopped at this soil level due to the presence of important secondary calcite precipitations, smectite and Fe-oxide accumulations. Mass balance calculations indicate that the enrichment process goes along with a volume increase relative to the bottom soil horizons.

  15. Inoculation stress hypothesis of environmental enrichment.

    Science.gov (United States)

    Crofton, Elizabeth J; Zhang, Yafang; Green, Thomas A

    2015-02-01

    One hallmark of psychiatric conditions is the vast continuum of individual differences in susceptibility vs. resilience resulting from the interaction of genetic and environmental factors. The environmental enrichment paradigm is an animal model that is useful for studying a range of psychiatric conditions, including protective phenotypes in addiction and depression models. The major question is how environmental enrichment, a non-drug and non-surgical manipulation, can produce such robust individual differences in such a wide range of behaviors. This paper draws from a variety of published sources to outline a coherent hypothesis of inoculation stress as a factor producing the protective enrichment phenotypes. The basic tenet suggests that chronic mild stress from living in a complex environment and interacting non-aggressively with conspecifics can inoculate enriched rats against subsequent stressors and/or drugs of abuse. This paper reviews the enrichment phenotypes, mulls the fundamental nature of environmental enrichment vs. isolation, discusses the most appropriate control for environmental enrichment, and challenges the idea that cortisol/corticosterone equals stress. The intent of the inoculation stress hypothesis of environmental enrichment is to provide a scaffold with which to build testable hypotheses for the elucidation of the molecular mechanisms underlying these protective phenotypes and thus provide new therapeutic targets to treat psychiatric/neurological conditions. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Evaluation of Methyl-Binding Domain Based Enrichment Approaches Revisited.

    Directory of Open Access Journals (Sweden)

    Karolina A Aberg

    Full Text Available Methyl-binding domain (MBD enrichment followed by deep sequencing (MBD-seq, is a robust and cost efficient approach for methylome-wide association studies (MWAS. MBD-seq has been demonstrated to be capable of identifying differentially methylated regions, detecting previously reported robust associations and producing findings that replicate with other technologies such as targeted pyrosequencing of bisulfite converted DNA. There are several kits commercially available that can be used for MBD enrichment. Our previous work has involved MethylMiner (Life Technologies, Foster City, CA, USA that we chose after careful investigation of its properties. However, in a recent evaluation of five commercially available MBD-enrichment kits the performance of the MethylMiner was deemed poor. Given our positive experience with MethylMiner, we were surprised by this report. In an attempt to reproduce these findings we here have performed a direct comparison of MethylMiner with MethylCap (Diagenode Inc, Denville, NJ, USA, the best performing kit in that study. We find that both MethylMiner and MethylCap are two well performing MBD-enrichment kits. However, MethylMiner shows somewhat better enrichment efficiency and lower levels of background "noise". In addition, for the purpose of MWAS where we want to investigate the majority of CpGs, we find MethylMiner to be superior as it allows tailoring the enrichment to the regions where most CpGs are located. Using targeted bisulfite sequencing we confirmed that sites where methylation was detected by either MethylMiner or by MethylCap indeed were methylated.

  17. Magnesium enriched lactic acid bacteria as a carrier for probiotic ice cream production.

    Science.gov (United States)

    Góral, Małgorzata; Kozłowicz, Katarzyna; Pankiewicz, Urszula; Góral, Dariusz

    2018-01-15

    The following strains of bacteria: Lactobacillus rhamnosus B 442, Lactobacillus rhamnosus 1937, and Lactococcus lactis JBB 500 were enriched with magnesium ions using Pulsed Electric Fields. The potentially probiotic strains were added to the mixture in the DVS process and applied for the production of ice cream which were then analyzed physicochemically and microbiologically. Results showed that addition of bacteria enriched with magnesium did not change chemical parameters of the ice cream and did not affect the freezing process, meltability, and hardness. No significant differences were noted in colour of the samples. The ice cream with addition of bacteria enriched with magnesium had higher adhesiveness. The results of viability determination showed that the total number of microorganisms in the ice cream was higher than in the starter cultures. Viability of the bacteria enriched with magnesium in the obtained ice cream was lower in comparison to the control samples. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Nitrogen enrichment regulates calcium sources in forests

    Science.gov (United States)

    Hynicka, Justin D.; Pett-Ridge, Julie C.; Perakis, Steven

    2016-01-01

    Nitrogen (N) is a key nutrient that shapes cycles of other essential elements in forests, including calcium (Ca). When N availability exceeds ecosystem demands, excess N can stimulate Ca leaching and deplete Ca from soils. Over the long term, these processes may alter the proportion of available Ca that is derived from atmospheric deposition vs. bedrock weathering, which has fundamental consequences for ecosystem properties and nutrient supply. We evaluated how landscape variation in soil N, reflecting long-term legacies of biological N fixation, influenced plant and soil Ca availability and ecosystem Ca sources across 22 temperate forests in Oregon. We also examined interactions between soil N and bedrock Ca using soil N gradients on contrasting basaltic vs. sedimentary bedrock that differed 17-fold in underlying Ca content. We found that low-N forests on Ca-rich basaltic bedrock relied strongly on Ca from weathering, but that soil N enrichment depleted readily weatherable mineral Ca and shifted forest reliance toward atmospheric Ca. Forests on Ca-poor sedimentary bedrock relied more consistently on atmospheric Ca across all levels of soil N enrichment. The broad importance of atmospheric Ca was unexpected given active regional uplift and erosion that are thought to rejuvenate weathering supply of soil minerals. Despite different Ca sources to forests on basaltic vs. sedimentary bedrock, we observed consistent declines in plant and soil Ca availability with increasing N, regardless of the Ca content of underlying bedrock. Thus, traditional measures of Ca availability in foliage and soil exchangeable pools may poorly reflect long-term Ca sources that sustain soil fertility. We conclude that long-term soil N enrichment can deplete available Ca and cause forests to rely increasingly on Ca from atmospheric deposition, which may limit ecosystem Ca supply in an increasingly N-rich world.

  19. Noble gas enrichment studies at JET

    International Nuclear Information System (INIS)

    Groth, M.; Andrew, P.; Fundamenski, W.; Guo, H.Y.; Hillis, D.L.; Hogan, J.T.; Horton, L.D.; Matthews, G.F.; Meigs, A.G.; Morgan, P.M.; Stamp, M.F.; Hellermann, M. von

    2001-01-01

    Adequate helium exhaust has been achieved in reactor-relevant ELMy H-mode plasmas in JET performed in the MKII AP and MKII GB divertor geometry. The divertor-characteristic quantities of noble gas compression and enrichment have been experimentally inferred from Charge Exchange Recombination Spectroscopy measurements in the core plasma, and from spectroscopic analysis of a Penning gauge discharge in the exhaust gas. The retention of helium was found to be satisfactory for a next-step device, with enrichment factors exceeding 0.1. The helium enrichment decreases with increasing core plasma density, while the neon enrichment has the opposite behaviour. Analytic and numerical analyses of these plasmas using the divertor impurity code package DIVIMP/NIMBUS support the explanation that the enrichment of noble gases depends significantly on the penetration depth of the impurity neutrals with respect to the fuel atoms. Changes of the divertor plasma configuration and divertor geometry have no effect on the enrichment

  20. Novel Membranes and Processes for Oxygen Enrichment

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Haiqing

    2011-11-15

    The overall goal of this project is to develop a membrane process that produces air containing 25-35% oxygen, at a cost of $25-40/ton of equivalent pure oxygen (EPO2). Oxygen-enriched air at such a low cost will allow existing air-fueled furnaces to be converted economically to oxygen-enriched furnaces, which in turn will improve the economic and energy efficiency of combustion processes significantly, and reduce the cost of CO{sub 2} capture and sequestration from flue gases throughout the U.S. manufacturing industries. During the 12-month Concept Definition project: We identified a series of perfluoropolymers (PFPs) with promising oxygen/nitrogen separation properties, which were successfully made into thin film composite membranes. The membranes showed oxygen permeance as high as 1,200 gpu and oxygen/nitrogen selectivity of 3.0, and the permeance and selectivity were stable over the time period tested (60 days). We successfully scaled up the production of high-flux PFP-based membranes, using MTR's commercial coaters. Two bench-scale spiral-wound modules with countercurrent designs were made and parametric tests were performed to understand the effect of feed flow rate and pressure, permeate pressure and sweep flow rate on the membrane module separation properties. At various operating conditions that modeled potential industrial operating conditions, the module separation properties were similar to the pure-gas separation properties in the membrane stamps. We also identified and synthesized new polymers [including polymers of intrinsic microporosity (PIMs) and polyimides] with higher oxygen/nitrogen selectivity (3.5-5.0) than the PFPs, and made these polymers into thin film composite membranes. However, these membranes were susceptible to severe aging; pure-gas permeance decreased nearly six-fold within two weeks, making them impractical for industrial applications of oxygen enrichment. We tested the effect of oxygen-enriched air on NO{sub x} emissions

  1. Surface enrichment with chrome and nitriding of IF steel under an abnormal glow discharge

    International Nuclear Information System (INIS)

    Meira, S.R.; Borges, P.C.; Bernardelli, E.A.

    2014-01-01

    The objective of this work is to evaluate the influence of surface enrichment of IF steel with chrome, and nitriding, the formation of the nitrided layer. Thus, IF steel samples were subjected to surface enrichment process, using 409 stainless steel as a target for sputtering, followed by plasma nitriding, both under a dc abnormal glow discharge. The enrichment treatment was operated at 1200 ° C for 3h. The nitriding treatment was operated at 510 ° C for 2 h. The influence of the treatments on the layers formed was studied through optical microscopy (OM), scan electron microscopy (SEM), X-ray diffraction (XRD) and Vickers microindentation. The results show that the enrichment is effective to enrich the IF surface, furthermore, improves the characteristics of nitriding, comparing nitriding samples to nitriding and enriched, was observed needles of nitrides, as well as a higher hardness, which is associated with the nitrides of chrome, on the nitriding and enriched samples. (author)

  2. Report of the Subcommittee on Domestic Uranium Enrichment

    International Nuclear Information System (INIS)

    1981-01-01

    A report by the Subcommittee on Domestic Uranium Enrichment to the Atomic Energy Commission is described; which covers the procedure of the domestic uranium enrichment by centrifugal process up to the commercial production, reviewing the current situation in this field. Domestic uranium enrichment is important in the aspects of securing stable enrichment service, establishing sound fuel cycle, and others. As the future target, the production around the year 2000 is set at 3,000 tons SWU per year at least. The business of uranium enrichment, which is now developed in the Power Reactor and Nuclear Fuel Development Corporation, is to be carried out by private enterprise. The contents are as follows: demand and supply balance of uranium enrichment service, significance of domestic uranium enrichment, evaluation of centrifugal uranium enrichment technology, the target of domestic uranium enrichment, the policy of domestic uranium enrichment promotion. (J.P.N.)

  3. 31 CFR 540.316 - Uranium enrichment.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Uranium enrichment. 540.316 Section 540.316 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... REGULATIONS General Definitions § 540.316 Uranium enrichment. The term uranium enrichment means the process of...

  4. A simplified treatment of radial enrichment distributions of LWR fuel assemblies in criticality calculations

    International Nuclear Information System (INIS)

    Hennebach, M.; Schnorrenberg, N.

    2008-01-01

    Criticality safety assessments are usually performed for fuel assembly models that are as generic as possible to encompass small modifications in geometry that have no impact on criticality. Dealing with different radial enrichment distributions for a fuel assembly type, which is especially important for BWR fuel, poses more of a challenge, since this characteristic is rather obviously influencing the neutronic behaviour of the system. Nevertheless, the large variability of enrichment distributions makes it very desirable and even necessary to treat them in a generalized way, both to keep the criticality safety assessment from becoming too unwieldy and to avoid having to extend it every time a new variation comes up. To be viable, such a generic treatment has to be demonstrably covering, i.e. lead to a higher effective neutron multiplication factor k eff than any of the radial enrichment distributions it represents. Averaging the enrichment evenly over the fuel rods of the assembly is a general and simple approach, and under reactor conditions, it is also a covering assumption: the graded distribution is introduced to achieve a linear power distribution, therefore reducing the enrichment of the better moderated rods at the edge of the assembly. With an even distribution of the average enrichment over all rods, these wellmoderated rods will cause increased fission rates at the assembly edges and a rise in k eff . Since the moderator conditions in a spent nuclear fuel cask differ strongly from a reactor even when considering optimal moderation, the proof that a uniform enrichment distribution is a covering assumption compared with detailed enrichment distributions has to be cask-specific. In this report, a method for making that proof is presented along with results for fuel assemblies from BWR reactors. All results are from three-dimensional Monte Carlo calculations with the SCALE 5.1 code package [1], using a 44-group neutron crosssection library based on ENDF

  5. Photochromic Polyurethanes Showing a Strong Change of Transparency and Refractive Index

    Directory of Open Access Journals (Sweden)

    Luca Oggioni

    2017-09-01

    Full Text Available Photochromic polymers have been studied as rewritable systems for optical elements with tunable transparency in the visible and refractive index in the NIR. Six diarylethene monomers have been synthesized to give thin films of photochromic polyurethanes. The absorption properties of the monomers in solution and of the corresponding polymeric films have been evaluated showing that a transparency contrast in the visible spectrum of the order of 10 3 can be obtained by a suitable choice of the chemical structure and illumination wavelength. The change in the refractive index in the NIR have been determined by ellipsometry showing changes larger than 10 − 2 . A trend of this variation with the absorption properties has been also highlighted. Fresnel lenses working on the basis of both a change of the transparency and the refractive index (amplitude and phase have been demonstrated.

  6. Boreal and temperate trees show strong acclimation of respiration to warming.

    Science.gov (United States)

    Reich, Peter B; Sendall, Kerrie M; Stefanski, Artur; Wei, Xiaorong; Rich, Roy L; Montgomery, Rebecca A

    2016-03-31

    Plant respiration results in an annual flux of carbon dioxide (CO2) to the atmosphere that is six times as large as that due to the emissions from fossil fuel burning, so changes in either will impact future climate. As plant respiration responds positively to temperature, a warming world may result in additional respiratory CO2 release, and hence further atmospheric warming. Plant respiration can acclimate to altered temperatures, however, weakening the positive feedback of plant respiration to rising global air temperature, but a lack of evidence on long-term (weeks to years) acclimation to climate warming in field settings currently hinders realistic predictions of respiratory release of CO2 under future climatic conditions. Here we demonstrate strong acclimation of leaf respiration to both experimental warming and seasonal temperature variation for juveniles of ten North American tree species growing for several years in forest conditions. Plants grown and measured at 3.4 °C above ambient temperature increased leaf respiration by an average of 5% compared to plants grown and measured at ambient temperature; without acclimation, these increases would have been 23%. Thus, acclimation eliminated 80% of the expected increase in leaf respiration of non-acclimated plants. Acclimation of leaf respiration per degree temperature change was similar for experimental warming and seasonal temperature variation. Moreover, the observed increase in leaf respiration per degree increase in temperature was less than half as large as the average reported for previous studies, which were conducted largely over shorter time scales in laboratory settings. If such dampening effects of leaf thermal acclimation occur generally, the increase in respiration rates of terrestrial plants in response to climate warming may be less than predicted, and thus may not raise atmospheric CO2 concentrations as much as anticipated.

  7. Atomics International fuel fabrication facility and low enrichment program. Part 2

    International Nuclear Information System (INIS)

    Hassel, H.W.

    1993-01-01

    Most of you know our company from the last meeting in May in Vienna, so I won't steal your time with explaining and demonstrating the same techniques that we have heard this morning f rom the other speakers. I would just take some words to explain the order of business with highly enriched uranium. NUKEM handles around almost two tons of highly enriched uranium a year and it was necessary to satisfy all the new physical protection philosophies. That means that we have to install storage and safe fabrication sites for a lot of money, 2.5 meter thick concrete walls, and different alarm systems. So just to demonstrate how silly this business is, we have just overcome this for highly enriched uranium, and now we speak about low enriched uranium for which we don't need all of these investments to make this business safe. I would just like to concentrate my words on the status of fabrication and considerations in my company concerning the medium enriched uranium and low enriched uranium. In TABLE I are the different fuel types (see column 1) and then we have the fabrication in column 2; (The reason that I use the blackboard this morning is that I try to demonstrate all the techniques. However, all the speakers before me did this and in theory we are not so far away from each other.) the experience of my company in kg. In column 3 is the irradiation experience of these fuels types. Column 4 shows the studies and calculations made in our company for lower and medium enriched fuels. The preliminary fabrication tests and calculations are in column 5, and in column 6 we have the delivery time for a prototype core in months after UF 6 supply. Column 7 shows the time for the development of specifications including irradiation time in years for 6 and 7, and column 8 is the estimated cost of 6 and 7. There is just one fuel that is not in this summary and that is U-Zr

  8. On the origin of a phosphate enriched interval in the Chattanooga Shale (Upper Devonian) of Tennessee-A combined sedimentologic, petrographic, and geochemical study

    Science.gov (United States)

    Li, Yifan; Schieber, Juergen

    2015-11-01

    The Devonian Chattanooga Shale contains an uppermost black shale interval with dispersed phosphate nodules. This interval extends from Tennessee to correlative strata in Kentucky, Indiana, and Ohio and represents a significant period of marine phosphate fixation during the Late Devonian of North America. It overlies black shales that lack phosphate nodules but otherwise look very similar in outcrop. The purpose of this study is to examine what sets these two shales apart and what this difference tells us about the sedimentary history of the uppermost Chattanooga Shale. In thin section, the lower black shales (PBS) show pyrite enriched laminae and compositional banding. The overlying phosphatic black shales (PhBS) are characterized by phosbioclasts, have a general banded to homogenized texture with reworked layers, and show well defined horizons of phosphate nodules that are reworked and transported. In the PhBS, up to 8000 particles of P-debris per cm2 occur in reworked beds, whereas the background black shale shows between 37-88 particles per cm2. In the PBS, the shale matrix contains between 8-16 phosphatic particles per cm2. The shale matrix in the PhBS contains 5.6% inertinite, whereas just 1% inertinite occurs in the PBS. The shale matrix in both units is characterized by flat REE patterns (shale-normalized), whereas Phosbioclast-rich layers in the PhBS show high concentrations of REEs and enrichment of MREEs. Negative Ce-anomalies are common to all samples, but are best developed in association with Phosbioclasts. Redox-sensitive elements (Co, U, Mo) are more strongly enriched in the PBS when compared to the PhBS. Trace elements associated with organic matter (Cu, Zn, Cd, Ni) show an inverse trend of enrichment. Deposited atop a sequence boundary that separates the two shale units, the PhBS unit represents a transgressive systems tract and probably was deposited in shallower water than the underlying PBS interval. The higher phosphate content in the PhBS is

  9. Nuclear material enrichment identification method based on cross-correlation and high order spectra

    International Nuclear Information System (INIS)

    Yang Fan; Wei Biao; Feng Peng; Mi Deling; Ren Yong

    2013-01-01

    In order to enhance the sensitivity of nuclear material identification system (NMIS) against the change of nuclear material enrichment, the principle of high order statistic feature is introduced and applied to traditional NMIS. We present a new enrichment identification method based on cross-correlation and high order spectrum algorithm. By applying the identification method to NMIS, the 3D graphs with nuclear material character are presented and can be used as new signatures to identify the enrichment of nuclear materials. The simulation result shows that the identification method could suppress the background noises, electronic system noises, and improve the sensitivity against enrichment change to exponential order with no system structure modification. (authors)

  10. Experience with environmental sampling at gas centrifuge enrichment plants

    International Nuclear Information System (INIS)

    Ekenstam, G. af; Bush, W.; Janov, J.; Kuhn, E.; Ryjinski, M.

    2001-01-01

    results obtained for two samples taken in May 1997 from the cascade hall at one of the enrichment plants. The evaluation of the results, using model enrichment calculations, showed that at least two enrichment processes had taken place - feeding with natural uranium and with recycled uranium. The effectiveness of environmental sampling was also demonstrated by analyzing a series of swipe samples taken at regular intervals in the process area of a newly commissioned centrifuge enrichment cascade in which the product enrichment was stepwise increased up to 5% 235 U. Experience is still being gained with environmental sampling at centrifuge enrichment plants but it is already considered to be a very useful technique, which allows determining past and current enrichment activities, in particular providing complementary assurance that no clandestine HEU production has occurred. Sampling both inside cascade areas and in cylinder filling and blending areas has proven to be useful and appropriate. A safeguards approach based on the traditional safeguards measures combined with environmental sampling for routine use is under development. This approach will enhance the efficiency of inspector's work in the field and the detection probability for clandestine activities

  11. Foraging enrichment modulates open field response to monosodium glutamate in mice.

    Science.gov (United States)

    Onaolapo, Olakunle J; Onaolapo, Adejoke Y; Akanmu, Moses A; Olayiwola, Gbola

    2015-07-01

    Environmental enrichment can enhance expression of species-specific behaviour. While foraging enrichment is encouraged in laboratory animals, its impact on novelty induced behaviour remain largely unknown. Here, we studied behavioural response of mice to acute and subchronic oral monosodium glutamate (MSG) in an open field with /without foraging enrichment. Adult male mice, assigned to five groups were administered vehicle (distilled water), or one of four selected doses of MSG (10, 20, 40 and 80 mg/kg) for 21 days. Open field novelty induced behaviours i.e. horizontal locomotion, rearing and grooming were assessed after the first and last doses of MSG. Results were analysed using MANOVA followed by Tukey HSD multiple comparison test and expressed as mean ± S.E.M. Following acute MSG administration without enrichment, locomotor activity reduced, grooming increased, while rearing activity reduced at lower doses and increased at higher doses. Subchronic administration without enrichment was associated with increased locomotor activity and reduction in grooming, rearing activity however still showed a biphasic response. Addition of enrichment with acute administration resulted in sustained reduction in locomotor and rearing activities with a biphasic grooming response. Subchronically, there was reduction in horizontal locomotion, biphasic rearing response and sustained increase in grooming activity. Behavioural response to varying doses of MSG as observed in the open field is affected by modifications such as foraging enrichment, which can reverse or dampen the central effects seen irrespective of duration of administration.

  12. The reduced enrichment program for JRR-4

    International Nuclear Information System (INIS)

    Takayanagi, M.

    1992-01-01

    Japan Research Reactor No. 4(JRR-4) with the rated power of 3.5 MW, swimming pool type research reactor, 93 % enriched uranium ETR-type fuel used, light water moderated and cooled. The first criticality reached on 28th January, 1965. The reactor has operated for about 26 years. However, it was planed to the reduced enrichment of the fuels to low enrichment according to the International Reduced Enrichment for Research and Test Reactors (RERTR) program. This paper describes the program for conversion of the enrichment of fuel from 93 % to less than 20 %. (author)

  13. Surface microlayer enrichment of volatile organic compounds and semi-volatile organic compounds in drinking water source.

    Science.gov (United States)

    Huang, Zhi; Zhou, Wen; Yu, Ya-juan; Zhang, Ai-qian; Han, Shuo-kui; Wang, Lian-sheng

    2004-01-01

    Enrichment of volatile organic compounds(VOC) and semi-volatility organic compounds(SVOC) in surface microlayer(SM) of three drinking water sources were studied. The enrichment factor(EFs) were 0.67 to 13.37 and 0.16 to 136, respectively. The results showed some VOC and most SVOC could enrich in SM. Some EFs of SVOC was quite high. Suspension and temperature could affect EFs of SVOC, slim wind and water movement do not destroy enrichment of organic in SM.

  14. Competing for the non-US enrichment markets

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    The article discusses three basic steps: first, the historical perspectives; second, where the enrichment industry and the non-US markets for enrichment stand today (the present situation); and third, the likely future developments, which, for practical purposes, are dealt with in two parts: the non-US enrichment markets in the 1980s; and the non-US enrichment markets beyond the 1980s;

  15. Enriched uranium sales: effect on supply industry

    International Nuclear Information System (INIS)

    Andersen, R.K.

    1985-01-01

    The subject is covered in sections: introduction (combined effect of low-enriched uranium (LEU) inventory sales and utility services enrichment contract terms); enrichment market overview; enrichment market dynamics; the reaction of the US Department of Energy; elimination of artificial demand; draw down of inventories; purchase and sale of LEU inventories; tails assay option; unfulfilled requirements for U 3 O 8 ; conclusions. (U.K.)

  16. Prenatal nutritional manipulation by in ovo enrichment influences bone structure, composition, and mechanical properties.

    Science.gov (United States)

    Yair, R; Shahar, R; Uni, Z

    2013-06-01

    The objective of this study was to examine the effect of embryonic nutritional enrichment on the development and properties of broiler leg bones (tibia and femur) from the prenatal period until maturity. To accomplish the objective, 300 eggs were divided into 2 groups: a noninjected group (control) and a group injected in ovo with a solution containing minerals, vitamins, and carbohydrates (enriched). Tibia and femur from both legs were harvested from chicks on embryonic days 19 (E19) and 21 (E21) and d 3, 7, 14, 28, and 54 posthatch (n = 8). The bones were mechanically tested (stiffness, maximal load, and work to fracture) and scanned in a micro-computed tomography (μCT) scanner to examine the structural properties of the cortical [cortical area, medullary area, cortical thickness, and maximal moment of inertia (Imax)] and trabecular (bone volume percent, trabecular thickness, and trabecular number) areas. To examine bone mineralization, bone mineral density (BMD) of the cortical area was obtained from the μCT scans, and bones were analyzed for the ash and mineral content. The results showed improved mechanical properties of the enriched group between E19 and d 3 and on d 14 (P bones), greater femoral cortical area on d 3, and greater Imax of both bones on d 14 (P bone trabecular architecture were that the enriched group had greater bone volume percent and trabecular thickness in the tibia on d 7 and the femur on d 28 (P mineralization between E19 and d 54 showed improved mineralization in the enriched group on E19 whereas on d 3 and 7, the control group showed a mineralization advantage, and on d 28 and 54, the enriched group showed again greater mineralization (P bone properties pre- and postnatally and showed that avian embryos are a good model for studying the effect of embryonic nutrition on natal and postnatal development. Most importantly, the enrichment led to improved mechanical properties until d 14 (roughly third of the lifespan of the bird), a big

  17. Stable isotope enrichment: Current and future potential

    International Nuclear Information System (INIS)

    Tracy, J.G.; Aaron, W.S.

    1992-01-01

    Oak Ridge National Laboratory (ORNL) operates the Isotope Enrichment Facility for the purpose of providing enriched stable isotopes, selected radioactive isotopes (including the actinides), and isotope-related materials and services for use in various research applications. ORNL is responsible for isotope enrichment and the distribution of approximately 225 nongaseous stable isotopes from 50 multi-isotopic elements. Many enriched isotope products are of prime importance in the fabrication of nuclear targets and the subsequent production of special radionuclides. State-of-the-art techniques to achieve special isotopic, chemical, and physical requirements are performed at ORNL This report describes the status and capabilities of the Isotope Enrichment Facility and the Isotope Research Materials Laboratory as well as emphasizing potential advancements in enrichment capabilities

  18. Stable isotope enrichment - current and future potential

    International Nuclear Information System (INIS)

    Tracy, J.G.; Aaron, W.S.

    1993-01-01

    Oak Ridge National Laboratory (ORNL) operates the Isotope Enrichment Facility for the purpose of providing enriched stable isotopes, selected radioactive isotopes (including the actinides), and isotope-related materials and services for use in various research applications. ORNL is responsible for isotope enrichment and the distribution of approximately 225 nongaseous stable isotopes from 50 multi-isotopic elements. Many enriched isotope products are of prime importance in the fabrication of nuclear targets and the subsequent production of special radionuclides. State-of-the-art techniques to achieve special isotopic, chemical, and physical requirements are performed at ORNL. This report describes the status and capabilities of the Isotope Enrichment Facility and the Isotope Research Materials Laboratory as well as emphasizing potential advancements in enrichment capabilities. (orig.)

  19. RERTR program progress in qualifying reduced-enrichment fuels

    International Nuclear Information System (INIS)

    Snelgrove, James L.

    1983-01-01

    In order to provide the technical means for reducing the enrichment of uranium used to fuel research and test reactors, the U.S. Reduced Enrichment Research and Test Reactor (RERTR) Program has been engaged in the development and testing of higher-uranium-density fuels than had been used previously. This fuel development effort included work to increase the density of fuels which were being used at the time the Program began and work on a fuel with the potential for much higher density. The ultimate goal of the fuel development and testing phase of the Program is to 'qualify' the fuel for use. A fuel is considered qualified when a sufficient data base for the fuel exists that it can be approved by regulating bodies for use in reactors. To convert a core to the use of reduced-enrichment fuel it is necessary to show that the core will behave properly during normal and off-normal operating conditions and to show that the fuel will behave properly to a reasonable margin beyond the conditions expected during normal operation. It is this latter area that this paper will address. The main characteristics to be considered in evaluating the performance of a fuel are its swelling, its blister-threshold temperature, and its metallurgical appearance. Data for the qualification of the reduced-enrichment fuels being developed by the RERTR Program are obtained from examination of miniature fuel plates (miniplates) which successfully pass the irradiation screening tests and from examinations of full-sized fuel elements. This paper will summarize the miniplate data reported in other papers presented during this meeting and will give the status of full-sized element irradiations. Finally, the current status of qualification of the various fuel types will be discussed and some projections of the future will be given

  20. U.S. forms uranium enrichment corporation

    International Nuclear Information System (INIS)

    Seltzer, R.

    1993-01-01

    After almost 40 years of operation, the federal government is withdrawing from the uranium enrichment business. On July 1, the Department of Energy turned over to a new government-owned entity--the US Enrichment Corp. (USEC)--both the DOE enrichment plants at Paducah, Ky., and Portsmouth, Ohio, and domestic and international marketing of enriched uranium from them. Pushed by the inability of DOE's enrichment operations to meet foreign competition, Congress established USEC under the National Energy Policy Act of 1992, envisioning the new corporation as the first step to full privatization. With gross revenues of $1.5 billion in fiscal 1992, USEC would rank 275th on the Fortune 500 list of top US companies. USEC will lease from DOE the Paducah and Portsmouth facilities, built in the early 1950s, which use the gaseous diffusion process for uranium enrichment. USEC's stock is held by the US Treasury, to which it will pay annual dividends. Martin Marietta Energy Systems, which has operated Paducah since 1984 and Portsmouth since 1986 for DOE, will continue to operate both plants for USEC. Closing one of the two facilities will be studied, especially in light of a 40% world surplus of capacity over demand. USEC also will consider other nuclear-fuel-related ventures. USEC will produce only low-enriched uranium, not weapons-grade material. Indeed, USEC will implement a contract now being completed under which the US will purchase weapons-grade uranium from dismantled Russian nuclear weapons and convert it into low-enriched uranium for power reactor fuel

  1. M DWARF LUMINOSITY, RADIUS, AND α-ENRICHMENT FROM I-BAND SPECTRAL FEATURES

    Energy Technology Data Exchange (ETDEWEB)

    Terrien, Ryan C.; Mahadevan, Suvrath; Bender, Chad F.; Deshpande, Rohit; Robertson, Paul, E-mail: rct151@psu.edu [Department of Astronomy and Astrophysics, The Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States)

    2015-03-20

    Despite the ubiquity of M dwarfs and their growing importance to studies of exoplanets, Galactic evolution, and stellar structure, methods for precisely measuring their fundamental stellar properties remain elusive. Existing techniques for measuring M dwarf luminosity, mass, radius, or composition are calibrated over a limited range of stellar parameters or require expensive observations. We find a strong correlation between the K{sub S}-band luminosity (M{sub K}), the observed strength of the I-band sodium doublet absorption feature, and [Fe/H] in M dwarfs without strong Hα emission. We show that the strength of this feature, coupled with [Fe/H] and spectral type, can be used to derive M dwarf M{sub K} and radius without requiring parallax. Additionally, we find promising evidence that the strengths of the I-band sodium doublet and the nearby I-band calcium triplet may jointly indicate α-element enrichment. The use of these I-band features requires only moderate-resolution near-infrared spectroscopy to provide valuable information about the potential habitability of exoplanets around M dwarfs, and surface gravity and distance for M dwarfs throughout the Galaxy. This technique has immediate applicability for both target selection and candidate planet–host system characterization for exoplanet missions such as TESS and K2.

  2. M DWARF LUMINOSITY, RADIUS, AND α-ENRICHMENT FROM I-BAND SPECTRAL FEATURES

    International Nuclear Information System (INIS)

    Terrien, Ryan C.; Mahadevan, Suvrath; Bender, Chad F.; Deshpande, Rohit; Robertson, Paul

    2015-01-01

    Despite the ubiquity of M dwarfs and their growing importance to studies of exoplanets, Galactic evolution, and stellar structure, methods for precisely measuring their fundamental stellar properties remain elusive. Existing techniques for measuring M dwarf luminosity, mass, radius, or composition are calibrated over a limited range of stellar parameters or require expensive observations. We find a strong correlation between the K S -band luminosity (M K ), the observed strength of the I-band sodium doublet absorption feature, and [Fe/H] in M dwarfs without strong Hα emission. We show that the strength of this feature, coupled with [Fe/H] and spectral type, can be used to derive M dwarf M K and radius without requiring parallax. Additionally, we find promising evidence that the strengths of the I-band sodium doublet and the nearby I-band calcium triplet may jointly indicate α-element enrichment. The use of these I-band features requires only moderate-resolution near-infrared spectroscopy to provide valuable information about the potential habitability of exoplanets around M dwarfs, and surface gravity and distance for M dwarfs throughout the Galaxy. This technique has immediate applicability for both target selection and candidate planet–host system characterization for exoplanet missions such as TESS and K2

  3. Enrichment from birth accelerates the functional and cellular development of a motor control area in the mouse.

    Directory of Open Access Journals (Sweden)

    Teresa Simonetti

    Full Text Available BACKGROUND: There is strong evidence that sensory experience in early life has a profound influence on the development of sensory circuits. Very little is known, however, about the role of experience in the early development of striatal networks which regulate both motor and cognitive function. To address this, we have investigated the influence of early environmental enrichment on motor development. METHODOLOGY/PRINCIPAL FINDINGS: Mice were raised in standard or enriched housing from birth. For animals assessed as adults, half of the mice had their rearing condition reversed at weaning to enable the examination of the effects of pre- versus post-weaning enrichment. We found that exclusively pre-weaning enrichment significantly improved performance on the Morris water maze compared to non-enriched mice. The effects of early enrichment on the emergence of motor programs were assessed by performing behavioural tests at postnatal day 10. Enriched mice traversed a significantly larger region of the test arena in an open-field test and had improved swimming ability compared to non-enriched cohorts. A potential cellular correlate of these changes was investigated using Wisteria-floribunda agglutinin (WFA staining to mark chondroitin-sulfate proteoglycans (CSPGs. We found that the previously reported transition of CSPG staining from striosome-associated clouds to matrix-associated perineuronal nets (PNNs is accelerated in enriched mice. CONCLUSIONS/SIGNIFICANCE: This is the first demonstration that the early emergence of exploratory as well as coordinated movement is sensitive to experience. These behavioural changes are correlated with an acceleration of the emergence of striatal PNNs suggesting that they may consolidate the neural circuits underlying these behaviours. Finally, we confirm that pre-weaning experience can lead to life long changes in the learning ability of mice.

  4. Uranium Conversion & Enrichment

    Energy Technology Data Exchange (ETDEWEB)

    Karpius, Peter Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-06

    The isotopes of uranium that are found in nature, and hence in ‘fresh’ Yellowcake’, are not in relative proportions that are suitable for power or weapons applications. The goal of conversion then is to transform the U3O8 yellowcake into UF6. Conversion and enrichment of uranium is usually required to obtain material with enough 235U to be usable as fuel in a reactor or weapon. The cost, size, and complexity of practical conversion and enrichment facilities aid in nonproliferation by design.

  5. Chemical processes for the extreme enrichment of tellurium into marine ferromanganese oxides

    Science.gov (United States)

    Kashiwabara, Teruhiko; Oishi, Yasuko; Sakaguchi, Aya; Sugiyama, Toshiki; Usui, Akira; Takahashi, Yoshio

    2014-04-01

    Tellurium, an element of growing economic importance, is extremely enriched in marine ferromanganese oxides. We investigated the mechanism of this enrichment using a combination of spectroscopic analysis and adsorption/coprecipitation experiments. X-ray Absorption Near-Edge Structure (XANES) analysis showed that in adsorption/coprecipitation systems, Te(IV) was oxidized on δ-MnO2 and not oxidized on ferrihydrite. Extended X-ray Absorption Fine Structure (EXAFS) analysis showed that both Te(IV) and Te(VI) were adsorbed on the surface of δ-MnO2 and ferrihydrite via formation of inner-sphere complexes. In addition, Te(VI) can be structurally incorporated into the linkage of Fe octahedra through a coprecipitation process because of its molecular geometry that is similar to the Fe octahedron. The largest distribution coefficient obtained in the adsorption/coprecipitation experiments was for the Te(VI)/ferrihydrite coprecipitation system, and it was comparable to those calculated from the distribution between natural ferromanganese oxides and seawater. Our XAFS and micro-focused X-ray fluorescence (μ-XRF) mapping of natural ferromanganese oxides showed that Te was structurally incorporated as Te(VI) in Fe (oxyhydr)oxide phases. We conclude that the main process for the enrichment of Te in ferromanganese oxides is structural incorporation of Te(VI) into Fe (oxyhydr)oxide phases through coprecipitation. This mechanism can explain the unique degree of enrichment of Te compared with other oxyanions, which are mainly enriched via adsorption on the surface of the solid structures. In particular, the great contrast in the distributions of Te and Se is caused by their oxidized species: (i) the similar geometry of the Te(VI) molecule to Fe octahedron, and (ii) quite soluble nature of Se(VI). Coexisting Mn oxide phases may promote structural incorporation of Te(VI) by oxidation of Te(IV), although the surface oxidation itself may not work as the critical enrichment process as

  6. Comparisons of significant parameters for a standard 20% enriched and FLIP 70% enriched TRIGA core

    International Nuclear Information System (INIS)

    Ringle, John C.; Anderson, Terrance V.; Johnson, Arthur G.

    1978-01-01

    A comparison is made between the 20% and 70% enriched cores. The initial start-up data for both cores show the FLIP needs ∼3.8 times the 235 U mass as the 20% core just to go critical. Operational configurations for both cores indicate a need for ∼33% additional fuel above initial critical for adequate maneuvering excess. The fuel element worths are higher in the central core locations for the 20% elements while the peripheral element worths are about the same (with some thermal flux peaking in the FLIP perheral elements). Pulsing comparisons of the two cores show significant differences in reactivity insertions and power peaks. (author)

  7. Uranium enrichment. Technology, economics, capacity

    International Nuclear Information System (INIS)

    Voigt, W.R. Jr.; Saire, D.E.; Gestson, D.K.; Peske, S.E.; Vanstrum, P.R.

    1983-01-01

    Large-scale enrichment of uranium has now been carried out for 40 years. While the gaseous diffusion process was the original choice of several countries and continues today to provide the major component of the world production of separative work, the last two decades have witnessed the development of a number of alternative processes for enrichment. These processes, which are being studied and deployed around the world, offer a wide range of technical and economic characteristics which will be useful in assuring adequate capacity to meet projected reactor fuel market needs through the rest of this century at competitive prices. With present uncertainties in future enriched uranium needs, it is apparent that flexibility in the deployment and operation of any enrichment process will be one of the prime considerations for the future. More economical production of separative work not only can have a beneficial impact on reactor fuel costs, but also tends to conserve natural uranium resources. This paper reviews the world scene in the enrichment component of the fuel cycle, including existing or planned commercial-scale facilities and announced R+D efforts on various processes. (author)

  8. Uranium enrichment: technology, economics, capacity

    Energy Technology Data Exchange (ETDEWEB)

    Voigt, Jr., W. R.; Vanstrum, P. R.; Saire, D. E.; Gestson, D. K.; Peske, S. E.

    1982-08-01

    Large-scale enrichment of uranium has now been carried out for 40 years. While the gaseous diffusion process was the original choice of several countries and continues today to provide the major component of the world production of separative work, the last two decades have witnessed the development of a number of alternative processes for enrichment. These processes, which are being studied and deployed around the world, offer a wide range of technical and economic characteristics which will be useful in assuring adequate capacity to meet projected reactor fuel market needs through the rest of this century at competitive prices. With present uncertainties in future enriched uranium needs, it is apparent that flexibility in the deployment and operation of any enrichment process will be one of the prime considerations for the future. More economical production of separative work not only can have a beneficial impact on reactor fuel costs, but also tends to conserve natural uranium resources. This paper reviews the world scene in the enrichment component of the fuel cycle, including existing or planned commercial-scale facilities and announced R and D efforts on various processes.

  9. Uranium enrichment: technology, economics, capacity

    International Nuclear Information System (INIS)

    Voigt, W.R. Jr.; Vanstrum, P.R.; Saire, D.E.; Gestson, D.K.; Peske, S.E.

    1982-01-01

    Large-scale enrichment of uranium has now been carried out for 40 years. While the gaseous diffusion process was the original choice of several countries and continues today to provide the major component of the world production of separative work, the last two decades have witnessed the development of a number of alternative processes for enrichment. These processes, which are being studied and deployed around the world, offer a wide range of technical and economic characteristics which will be useful in assuring adequate capacity to meet projected reactor fuel market needs through the rest of this century at competitive prices. With present uncertainties in future enriched uranium needs, it is apparent that flexibility in the deployment and operation of any enrichment process will be one of the prime considerations for the future. More economical production of separative work not only can have a beneficial impact on reactor fuel costs, but also tends to conserve natural uranium resources. This paper reviews the world scene in the enrichment component of the fuel cycle, including existing or planned commercial-scale facilities and announced R and D efforts on various processes

  10. Integrative set enrichment testing for multiple omics platforms

    Directory of Open Access Journals (Sweden)

    Poisson Laila M

    2011-11-01

    Full Text Available Abstract Background Enrichment testing assesses the overall evidence of differential expression behavior of the elements within a defined set. When we have measured many molecular aspects, e.g. gene expression, metabolites, proteins, it is desirable to assess their differential tendencies jointly across platforms using an integrated set enrichment test. In this work we explore the properties of several methods for performing a combined enrichment test using gene expression and metabolomics as the motivating platforms. Results Using two simulation models we explored the properties of several enrichment methods including two novel methods: the logistic regression 2-degree of freedom Wald test and the 2-dimensional permutation p-value for the sum-of-squared statistics test. In relation to their univariate counterparts we find that the joint tests can improve our ability to detect results that are marginal univariately. We also find that joint tests improve the ranking of associated pathways compared to their univariate counterparts. However, there is a risk of Type I error inflation with some methods and self-contained methods lose specificity when the sets are not representative of underlying association. Conclusions In this work we show that consideration of data from multiple platforms, in conjunction with summarization via a priori pathway information, leads to increased power in detection of genomic associations with phenotypes.

  11. Comprehensive evaluation of disease- and trait-specific enrichment for eight functional elements among GWAS-identified variants.

    Science.gov (United States)

    Markunas, Christina A; Johnson, Eric O; Hancock, Dana B

    2017-07-01

    Genome-wide association study (GWAS)-identified variants are enriched for functional elements. However, we have limited knowledge of how functional enrichment may differ by disease/trait and tissue type. We tested a broad set of eight functional elements for enrichment among GWAS-identified SNPs (p Enrichment analyses were conducted using logistic regression, with Bonferroni correction. Overall, a significant enrichment was observed for all functional elements, except sequence motifs. Missense SNPs showed the strongest magnitude of enrichment. eQTLs were the only functional element significantly enriched across all diseases/traits. Magnitudes of enrichment were generally similar across diseases/traits, where enrichment was statistically significant. Blood vs. brain tissue effects on enrichment were dependent on disease/trait and functional element (e.g., cardiovascular disease: eQTLs P TissueDifference  = 1.28 × 10 -6 vs. enhancers P TissueDifference  = 0.94). Identifying disease/trait-relevant functional elements and tissue types could provide new insight into the underlying biology, by guiding a priori GWAS analyses (e.g., brain enhancer elements for psychiatric disease) or facilitating post hoc interpretation.

  12. Development of long-life low enrichment fuel

    International Nuclear Information System (INIS)

    Gietzen, A.J.; West, G.B.

    1978-01-01

    With only a few exceptions, TRIGA reactors have always used low-enriched-uranium (LEU) fuel with an enrichment of 19.9%. The exceptions have either been converted from the standard low-enriched fuel to the 70% enriched FLIP fuel in order to achieve extended lifetime, or are higher powered reactors which were designed for long life using 93%-enriched uranium during the time when the use and export of highly enriched uranium (HEU) was not restricted. The advent of international policies focusing attention on non-proliferation and safeguards made the HEU fuels obsolete. General Atomic immediately undertook a development effort (nearly two years ago) in order to be in a position to comply with these policies for all future export sales and also to provide a low-enriched alternative to fully enriched plate-type fuels. This important work was subsequently partially supported by the U. S. Department of Energy. The laboratory and production tests have shown that higher uranium densities can be achieved to compensate for reducing the enrichment to 20%, and that the fuels maintain the characteristics of the very thoroughly proven standard TRIGA fuels. In May of this year, General Atomic announced that these fuels were available for TRIGA reactors and for plate-type reactors with power levels up to 15 MW with GA's standard commercial warranty

  13. H.R. 788: This Act may be cited as the Uranium Enrichment Reorganization Act, introduced in the House of Representatives, One Hundred Second Congress, First Session, February 4, 1991

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    This bill would maintain a competitive, financially strong, and secure uranium enrichment capability in the US by reorganizing the uranium enrichment enterprise. The bill amends the Atomic Energy Act of 1954 by establishing the United States Uranium Enrichment Corporation. This bill describes general provisions; the establishment of the corporation; powers and duties of the corporation; organization, finance, and management; licensing, taxation, and miscellaneous provisions; decontamination, decommissioning, and remedial action

  14. Enrichment and Determination of radionuclides by ion chromatography

    International Nuclear Information System (INIS)

    ZAFIMANJATO, J.L.R.

    1996-01-01

    The fundamentals of Ion Chromatography (IC) and Liquid Scintillation Counting (LSC) are reviewed. Ion Chromatography as separation method for cations is coupled with Liquid Scintillation Counting for the determination of Radionuclides in water samples. An experimental arrangement for investigations on the applicability of guard columns for cationic radionuclide enrichment is shown. The saturation behaviour of single and bivalentic cations and their combination is presented. Our results show that radioactive bivalentic cations like strontium-90 and radium-226 are enriched on a Ion Pac CG 12 Dionex guard column from 100 to 300ml natural water in one single step. The procedure is suitable for their determination in concentrations down to 10 -2 Bq.l -1 [fr

  15. Influence of environmental enrichment on the behavior and physiology of mice infected by Trypanosoma cruzi

    Directory of Open Access Journals (Sweden)

    Déborah Maria Moreira da Silva

    Full Text Available Abstract INTRODUCTION: Enriched environments normally increase behavioral repertoires and diminish the expression of abnormal behaviors and stress-related physiological problems in animals. Although it has been shown that experimental animals infected with microorganisms can modify their behaviors and physiology, few studies have evaluated how environmental enrichment affects these parameters. This study aimed to evaluate the effects of environmental enrichment on the behavior and physiology of confined mice infected with Trypanosoma cruzi. METHODS: The behaviors of 20 T. cruzi-infected mice and 20 non-infected mice were recorded during three treatments: baseline, enrichment, and post-enrichment. Behavioral data were collected using scan sampling with instantaneous recording of behavior every 30s, totaling 360h. Plasma TNF, CCL2, and IL-10 levels and parasitemia were also evaluated in infected enriched/non-enriched mice. Behavioral data were evaluated by Friedman’s test and physiological data by one-way ANOVA and area under the curve (AUC analysis. RESULTS: Results showed that environmental enrichment significantly increased exploratory behaviors and diminished inactivity. The use of environmental enrichment did not diminish circulating levels of TNF and IL-10 but diminished circulating levels of CCL2 and parasitemia. CONCLUSIONS: Positive behavioral and physiological effects of environmental enrichment were observed in mice living in enriched cages. Thus, environmental enrichment improved the welfare of these animals.

  16. World enrichment requirements to 2005

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    The primary enrichment suppliers-Eurodif, Techsnabexport, Urenco, and the US DOE - are positioning themselves to take advantage of the post - 1995 market. Overall, unfilled requirements represent about 40 percent of world requirements in the year 2000. The USA will be the primary market, as US utilities' unfilled enrichment requirements account for over 60 percent of the world's total unfilled requirements. The enrichment market is moving toward more global competition, as each supplier tries to maintain its current regional market base and then to capture additional market share in other regions

  17. Irradiation behavior of low-enriched U/sub 6/Fe-Al dispersion fuel elements

    Energy Technology Data Exchange (ETDEWEB)

    Hofman, G.L.; Domagala, R.F.; Copeland, G.L.

    1987-10-01

    An irradiation test of miniature fuel plates containing low-enriched (20% /sup 235/U)U/sub 6/Fe dispersed and clad in Al was performed. The postirradiation examination shows U/sub 6/Fe to form extensive fission gas bubbles at burnups of only approx. = 20% of the original 20% fuel enrichment. Plate failure by fission gas-driven pillowing occurred at approx. = 40% burnup. This places U/sub 6/FE at the lowest burnup capability among low enriched dispersion fuels that have been tested for use in research and test reactors

  18. DOE enrichment plants-safeguards means business

    International Nuclear Information System (INIS)

    Donnelly, R.

    1987-01-01

    The Portsmouth Gaseous Diffusion Plant, owned by the US Department of Energy (DOE) and operated by Martin Marietta Energy Systems, Inc., is a full service enrichment plant. Its long enriching cascade can process uranium hexafluoride (UF 6 ) feeds at almost any 235 U level and can produce UF 6 over the complete spectrum from depleted to very highly enriched uranium. The DOE uranium enrichment program is a government-owned enterprise operating as a business. The operating concerns of the DOE uranium enrichment plants and their safeguards programs have evolved together over the past three decades, and that evolution will likely continue. As the risk associated with possession, processing, and shipment of strategic nuclear material increased, the protection and control of it increased; as the value of the product grew with time, better ways were found to measure and conserve it. In each of these areas, safeguards objectives and the business requirements of the plant are complementary, and the progress made in one area has been reflected by progress in the other. The plant's material control and accountability program has become crucial to such business requirements as quantifying the enriched uranium (separative work units) produced in each monthly period and convincing financial auditors that the multibillion dollar enriched uranium assets located at the Portsmouth plant are properly stated

  19. Uranium enrichment

    International Nuclear Information System (INIS)

    1991-08-01

    This paper reports that in 1990 the Department of Energy began a two-year project to illustrate the technical and economic feasibility of a new uranium enrichment technology-the atomic vapor laser isotope separation (AVLIS) process. GAO believes that completing the AVLIS demonstration project will provide valuable information about the technical viability and cost of building an AVLIS plant and will keep future plant construction options open. However, Congress should be aware that DOE still needs to adequately demonstrate AVLIS with full-scale equipment and develop convincing cost projects. Program activities, such as the plant-licensing process, that must be completed before a plant is built, could take many years. Further, an updated and expanded uranium enrichment analysis will be needed before any decision is made about building an AVLIS plant. GAO, which has long supported legislation that would restructure DOE's uranium enrichment program as a government corporation, encourages DOE's goal of transferring AVLIS to the corporation. This could reduce the government's financial risk and help ensure that the decision to build an AVLIS plant is based on commercial concerns. DOE, however, has no alternative plans should the government corporation not be formed. Further, by curtailing a planned public access program, which would have given private firms an opportunity to learn about the technology during the demonstration project, DOE may limit its ability to transfer AVLIS to the private sector

  20. Chronic nutrient enrichment increases prevalence and severity of coral disease and bleaching.

    Science.gov (United States)

    Vega Thurber, Rebecca L; Burkepile, Deron E; Fuchs, Corinne; Shantz, Andrew A; McMinds, Ryan; Zaneveld, Jesse R

    2014-02-01

    Nutrient loading is one of the strongest drivers of marine habitat degradation. Yet, the link between nutrients and disease epizootics in marine organisms is often tenuous and supported only by correlative data. Here, we present experimental evidence that chronic nutrient exposure leads to increases in both disease prevalence and severity and coral bleaching in scleractinian corals, the major habitat-forming organisms in tropical reefs. Over 3 years, from June 2009 to June 2012, we continuously exposed areas of a coral reef to elevated levels of nitrogen and phosphorus. At the termination of the enrichment, we surveyed over 1200 scleractinian corals for signs of disease or bleaching. Siderastrea siderea corals within enrichment plots had a twofold increase in both the prevalence and severity of disease compared with corals in unenriched control plots. In addition, elevated nutrient loading increased coral bleaching; Agaricia spp. of corals exposed to nutrients suffered a 3.5-fold increase in bleaching frequency relative to control corals, providing empirical support for a hypothesized link between nutrient loading and bleaching-induced coral declines. However, 1 year later, after nutrient enrichment had been terminated for 10 months, there were no differences in coral disease or coral bleaching prevalence between the previously enriched and control treatments. Given that our experimental enrichments were well within the ranges of ambient nutrient concentrations found on many degraded reefs worldwide, these data provide strong empirical support to the idea that coastal nutrient loading is one of the major factors contributing to the increasing levels of both coral disease and coral bleaching. Yet, these data also suggest that simple improvements to water quality may be an effective way to mitigate some coral disease epizootics and the corresponding loss of coral cover in the future. © 2013 John Wiley & Sons Ltd.

  1. Evaporated self-supporting foils of enriched iron from the in-situ reduction of Fe2O3

    International Nuclear Information System (INIS)

    Riel, W.D.

    1976-01-01

    This paper describes the reduction of isotopically enriched Fe 2 O 3 usng a controlled thermite reaction. The method will produce strain free evaporated films of 100-300 μg/cm 2 which can be floated and mounted, using standard techniques, to make strong self-supporting targets. (author)

  2. Availability of enrichment services

    International Nuclear Information System (INIS)

    Svenke, E.

    1977-01-01

    The report summarizes major uncertainties which are likely to influence future demands for uranium isotopic enrichment. Since for the next decade the development of nuclear power will be largely concerned with the increment in demand the timely need for enrichment capacity will be particularly sensitive to assumptions about growth rates. Existing worldwide capacity together with capacities under construction will be sufficient well into the 1980's. However, long decision and construction leadtime, uncertainty as to future demand as well as other factors, specifically high capital need, all of which entail financial risks, create hindrances to a timely development of increment. The adequacy of current technology is well demonstrated in plant operation and new technology is under way. Technology is, however, not freely available on a purely commercial basis. Commercial willingness, which anticipates a limited degree of financial risk, is requesting both long term back-up from the utilities that would parallel their firm decisions on the acquisition of nuclear power units, and a protective government umbrella. This situation depends on the symbiotic relationship that exists between the nuclear power generating organizations, the enrichment undertakings and the governments involved. The report accordingly stresses the need for a more cooperative approach and this, moreover, at the multinational level. There is otherwise a risk that proper resources and financing means will not be allocated to the enrichment sector. Export limitations that request the highest degree of industrial processing of nuclear fuel, i.e. the compulsory enrichment of natural uranium, do not serve the interests of overall industrial efficiency

  3. Separation/enrichment of trace Zinc using potassium bromide-dimethylglyoxime-thymolphthalein system

    Science.gov (United States)

    Tu, Changqing; Wen, Xinrong

    2018-02-01

    A new method for the separation enrichment of trace Zn2+ using microcrystalline thymolphthalein as an adsorbent was established. The separation enrichment behaviour of Zn2+ and the conditions for the separation quantitatively of Zn2+ with other metal ions were investigated. The possible separation enrichment mechanism of Zn2+ was discussed in detail. The results showed that by controlling pH 10.0, in KBr-diacetydioxime(DMG)-thymolphthalein(TP) system, chelate settlement of Zn(DMG)2 which formed by Zn2+ and DMG was quantitatively adsorbed on the surface of microcrystalline thymolphthalein,and the liquid-solid phases were formed with clear interface, while Cu2+, Bi3+, Al3+, Hg2+ could not be adsorbed. The quantitative separation of Zn2+ from those metal ions was achieved. The proposed method has been successfully applied to the quantitative separation of trace Zn2+ in synthetic water samples with enrichment yield of 93.5%∼99.3%.

  4. Abortion: Strong's counterexamples fail

    DEFF Research Database (Denmark)

    Di Nucci, Ezio

    2009-01-01

    This paper shows that the counterexamples proposed by Strong in 2008 in the Journal of Medical Ethics to Marquis's argument against abortion fail. Strong's basic idea is that there are cases--for example, terminally ill patients--where killing an adult human being is prima facie seriously morally...

  5. Civilian inventories of plutonium and highly enriched uranium

    International Nuclear Information System (INIS)

    Albright, D.

    1987-01-01

    In the future, commercial laser isotope enrichment technologies, currently under development, could make it easier for national to produce highly enriched uranium secretly. The head of a US firm that is developing a laser enrichment process predicts that in twenty years, major utilities and small countries will have relatively small, on-site, laser-based uranium enrichment facilities. Although these plants will be designed for the production of low enriched uranium, they could be modified to produce highly enriched uranium, an option that raises the possibility of countries producing highly enriched uranium in small, easily hidden facilities. Against this background, most of this report describes the current and future quantities of plutonium and highly enriched uranium in the world, their forms, the facilities in which they are produced, stored, and used, and the extent to which they are transported. 5 figures, 10 tables

  6. NRC licensing of uranium enrichment plants

    International Nuclear Information System (INIS)

    Moran, B.W.

    1991-01-01

    The US Nuclear Regulatory Commission (NRC) is preparing a rule making that establishes the licensing requirements for low-enriched uranium enrichment plants. Although implementation of this rule making is timed to correspond with receipt of a license application for the Louisiana Energy Services centrifuge enrichment plant, the rule making is applicable to all uranium enrichment technologies. If ownership of the US gaseous diffusion plants and/or atomic vapor laser isotope separation is transferred to a private or government corporation, these plants also would be licensable under the new rule making. The Safeguards Studies Department was tasked by the NRC to provide technical assistance in support of the rule making and guidance preparation process. The initial and primary effort of this task involved the characterization of the potential safeguards concerns associated with a commercial enrichment plant, and the licensing issues associated with these concerns. The primary safeguards considerations were identified as detection of the loss of special nuclear material, detection of unauthorized production of material of low strategic significance, and detection of production of uranium enriched to >10% 235 U. The primary safeguards concerns identified were (1) large absolute limit of error associated with the material balance closing, (2) the inability to shutdown some technologies to perform a cleanout inventory of the process system, and (3) the flexibility of some technologies to produce higher enrichments. Unauthorized production scenarios were identified for some technologies that could prevent conventional material control and accounting programs from detecting the production and removal of 5 kg 235 U as highly enriched uranium. Safeguards techniques were identified to mitigate these concerns

  7. Environmental enrichment choices of shelter cats.

    Science.gov (United States)

    Ellis, J J; Stryhn, H; Spears, J; Cockram, M S

    2017-08-01

    Choices made by cats between different types of environmental enrichment may help shelters to prioritize how to most effectively enrich cat housing, especially when limited by space or funds. This study investigates the environmental enrichment use of cats in a choice test. Twenty-six shelter cats were kept singularly in choice chambers for 10days. Each chamber had a central area and four centrally-linked compartments containing different types of environmental enrichment: 1) an empty control, 2) a prey-simulating toy, 3) a perching opportunity, and 4) a hiding opportunity. Cat movement between compartments was quantitatively recorded using a data-logger. Enriched compartments were visited significantly more frequently during the light period than during the dark period. Cats spent a significantly greater percentage of time in the hiding compartment (median=55%, IQR=46) than in the toy compartment (median=2%, IQR=9), or in the empty control compartment (median=4%, IQR=4). These results provide additional evidence to support the value of a hiding box to cats housed in a novel environment, in that they choose hiding relative to other types of environmental enrichment. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Strong-back safety latch

    International Nuclear Information System (INIS)

    DeSantis, G.N.

    1995-01-01

    The calculation decides the integrity of the safety latch that will hold the strong-back to the pump during lifting. The safety latch will be welded to the strong-back and will latch to a 1.5-in. dia cantilever rod welded to the pump baseplate. The static and dynamic analysis shows that the safety latch will hold the strong-back to the pump if the friction clamps fail and the pump become free from the strong-back. Thus, the safety latch will meet the requirements of the Lifting and Rigging Manual for under the hook lifting for static loading; it can withstand shock loads from the strong-back falling 0.25 inch

  9. Feasibility of nondestructive assay measurements in uranium enrichment plants

    Energy Technology Data Exchange (ETDEWEB)

    Walton, R.B.

    1978-04-01

    Applications of nondestructive assay methods to measurement problems in uranium enrichment facilities are reviewed. The results of a number of test and evaluation projects that were performed over the last decade at ORGDP and Portsmouth are presented. Measurements of the residual holdup in the top enrichment portion of the shut-down K-25 cascade were made with portable neutron and gamma-ray detectors, and inventory estimates based on these data were in good agreement with ORGDP estimates. In the operating cascade, the tests showed that portable NaI detectors are effective for monitoring NaF and alumina media for gaseous effluent traps and that gas phase enrichments and inventories, as well as large deposits of uranium, can be detected with portable neutron and gamma-ray instrumentation. A wide variety of scrap and waste materials, including barrier and compressor blades, incinerator ash and trapping media, and miscellaneous waste, were measured using passive gamma-ray and neutron methods and 14-MeV neutron interrogation. Methods developed for rapid verification of UF/sub 6/ in shipping containers with portable neutron and gamma-ray instruments are now used routinely by safeguards inspectors. Passive assay methods can also be used to measure continuously the enrichments of /sup 235/U and /sup 234/U in the UF/sub 6/ product and tails withdrawals of a gaseous diffusion plant. A system that was developed and installed in the extended-range product withdrawal station of the Portsmouth facility measures enrichment with a relative accuracy of 0.5%. A stand-alone neutron detector has also been successfully evaluated for the measurement of the isotopic abundance of /sup 234/U in UF/sub 6/ in sample cylinders, an application of potential importance to Minor Isotope Safeguards Technology. Recommendations are made on the role of NDA measurements for enrichment plant safeguards, including additional tests and evaluations that may be needed, particularly for advanced uranium

  10. Uranium enrichment: heading for a cliff

    International Nuclear Information System (INIS)

    Norman, C.

    1987-01-01

    Thanks to drastic cost cutting in the past 2 years, US enrichment plants now have the lowest cost production in the world, but US prices are still higher than those of overseas competitors because the business is paying for past mistakes. The most serious difficulty is that the Department of Energy (DOE), which owns and operates the US enrichment enterprise, is paying more than $500 million a year to the Tennessee Valley Authority (TVA) for electricity it once thought it would need but no longer requires. Another is that billions of dollars were spent in the 1970s and early 1980s to build new capacity that is now not needed. As a result, the enrichment enterprise has accumulated a debt to the US Treasury that the General Accounting Office (GAO) estimates at $8.8 billion. This paper presents the background and current debate in Congress about the difficulties facing the enrichment industry. In the midst of this debate over the future of the enterprise, the development of the next generation of enrichment technology is being placed in jeopardy. Known as atomic vapor laser isotope separation, or AVLIS, the process was viewed as the key to the long-term competitiveness of US enrichment. As the federal deficit mounted, however, funding for the AVLIS program was cut back and the timetable was stretched out. The US enrichment program has reached the point at which Congress will be forced to make some politically difficult decisions

  11. Effects of shelter and enrichment on the ecology and nutrient cycling of microbial communities of subtidal carbonate sediments.

    Science.gov (United States)

    Forehead, Hugh I; Kendrick, Gary A; Thompson, Peter A

    2012-04-01

    The interactions between physical disturbances and biogeochemical cycling are fundamental to ecology. The benthic microbial community controls the major pathway of nutrient recycling in most shallow-water ecosystems. This community is strongly influenced by physical forcing and nutrient inputs. Our study tests the hypotheses that benthic microbial communities respond to shelter and enrichment with (1) increased biomass, (2) change in community composition and (3) increased uptake of inorganic nutrients from the water column. Replicate in situ plots were sheltered from physical disturbance and enriched with inorganic nutrients or left without additional nutrients. At t(0) and after 10 days, sediment-water fluxes of nutrients, O(2) and N(2) , were measured, the community was characterized with biomarkers. Autochthonous benthic microalgal (BMA) biomass increased 30% with shelter and a natural fivefold increase in nutrient concentration; biomass did not increase with greater enrichment. Diatoms remained the dominant taxon of BMA, suggesting that the sediments were not N or Si limited. Bacteria and other heterotrophic organisms increased with enrichment and shelter. Daily exchanges of inorganic nutrients between sediments and the water column did not change in response to shelter or nutrient enrichment. In these sediments, physical disturbance, perhaps in conjunction with nutrient enrichment, was the primary determinant of microbial biomass. © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  12. Safety of uranium enrichment plant

    International Nuclear Information System (INIS)

    Yonekawa, Shigeru; Morikami, Yoshio; Morita, Minoru; Takahashi, Tsukasa; Tokuyasu, Takashi.

    1991-01-01

    With respect to safety evaluation of the gas centrifuge enrichment facility, several characteristic problems are described as follows. Criticality safety in the cascade equipments can be obtained to maintain the enrichment of UF 6 below 5 %. External radiation dose equivalent rate of the 30B cylinder is low enough, the shield is not necessary. Penetration ratio of the two-stage HEPA filters for UF 6 aerosol is estimated at 10 -9 . From the experimental investigation, vacuum tightness is not damaged by destruction of gas centrifuge rotor. Carbon steel can be used for uranium enrichment equipments under the condition below 100degC. (author)

  13. Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice.

    Science.gov (United States)

    Yamaguchi, Hiroshi; Hara, Yuta; Ago, Yukio; Takano, Erika; Hasebe, Shigeru; Nakazawa, Takanobu; Hashimoto, Hitoshi; Matsuda, Toshio; Takuma, Kazuhiro

    2017-08-30

    We recently demonstrated that prenatal exposure to valproic acid (VPA) at embryonic day 12.5 causes autism spectrum disorder (ASD)-like phenotypes such as hypolocomotion, anxiety-like behavior, social deficits and cognitive impairment in mice and that it decreases dendritic spine density in the hippocampal CA1 region. Previous studies show that some abnormal behaviors are improved by environmental enrichment in ASD rodent models, but it is not known whether environmental enrichment improves cognitive impairment. In the present study, we examined the effects of early environmental enrichment on behavioral abnormalities and neuromorphological changes in prenatal VPA-treated mice. We also examined the role of dendritic spine formation and synaptic protein expression in the hippocampus. Mice were housed for 4 weeks from 4 weeks of age under either a standard or enriched environment. Enriched housing was found to increase hippocampal brain-derived neurotrophic factor mRNA levels in both control and VPA-exposed mice. Furthermore, in VPA-treated mice, the environmental enrichment improved anxiety-like behavior, social deficits and cognitive impairment, but not hypolocomotion. Prenatal VPA treatment caused loss of dendritic spines in the hippocampal CA1 region and decreases in mRNA levels of postsynaptic density protein-95 and SH3 and multiple ankyrin repeat domains 2 in the hippocampus. These hippocampal changes were improved by the enriched housing. These findings suggest that the environmental enrichment improved most ASD-like behaviors including cognitive impairment in the VPA-treated mice by enhancing dendritic spine function. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Enrichment behavior and transport mechanism of soil-bound PAHs during rainfall-runoff events

    International Nuclear Information System (INIS)

    Zheng Yi; Luo Xiaolin; Zhang Wei; Wu Bin; Han Feng; Lin Zhongrong; Wang Xuejun

    2012-01-01

    Polycyclic Aromatic Hydrocarbons (PAHs) transported by surface runoff result in nonpoint source pollution and jeopardize aquatic ecosystems. The transport mechanism of PAHs during rainfall-runoff events has been rarely studied regarding pervious areas. An experimental system was setup to simulate the runoff pollution process on PAHs-contaminated soil. The enrichment behavior of soil-bound PAHs was investigated. The results show that soil organic matters (SOM), rather than clay particles, seem to be the main carrier of PAHs. The enrichment is highly conditioned on runoff and erosion processes, and its magnitude varies among PAH compounds. It is not feasible to build a simple and universal relationship between enrichment ratio and sediment discharge following the traditional enrichment theory. To estimate the flux of PAHs from pervious areas, soil erosion process has to be clearly understood, and both organic carbon content and composition of SOM should be factored into the calculation. - Highlights: ► Significant enrichment of particle-bound PAHs during rainfall-runoff events. ► Organic matters as the direct carrier of PAHs in runoff from contaminated soil. ► The traditional enrichment theory is not fully valid for PAHs. - The traditional enrichment theory is not fully valid for PAHs, and soil organic matters have a significant impact on the transport of PAHs during rainfall-runoff events.

  15. A Resolution of the Paradox of Enrichment

    Science.gov (United States)

    Feng, Z. C.; Li, Y. Charles

    2015-06-01

    The paradox of enrichment was observed by Rosenzweig [1971] in a class of predator-prey models. Two of the parameters in the models are crucial for the paradox. These two parameters are the prey's carrying capacity and prey's half-saturation for predation. Intuitively, increasing the carrying capacity due to enrichment of the prey's environment should lead to a more stable predator-prey system. Analytically, it turns out that increasing the carrying capacity always leads to an unstable predator-prey system that is susceptible to extinction from environmental random perturbations. This is the so-called paradox of enrichment. Our resolution here rests upon a closer investigation on a dimensionless number H formed from the carrying capacity and the prey's half-saturation. By recasting the models into dimensionless forms, the models are in fact governed by a few dimensionless numbers including H. The effects of the two parameters: carrying capacity and half-saturation are incorporated into the number H. In fact, increasing the carrying capacity is equivalent (i.e. has the same effect on H) to decreasing the half-saturation which implies more aggressive predation. Since there is no paradox between more aggressive predation and instability of the predator-prey system, the paradox of enrichment is resolved. The so-called instability of the predator-prey system is characterized by the existence of a stable limit cycle in the phase plane, which gets closer and closer to the predator axis and prey axis. Due to random environmental perturbations, this can lead to extinction. We also further explore spatially dependent models for which the phase space is infinite-dimensional. The spatially independent limit cycle which is generated by a Hopf bifurcation from an unstable steady state, is linearly stable in the infinite-dimensional phase space. Numerical simulations indicate that the basin of attraction of the limit cycle is riddled. This shows that spatial perturbations can

  16. Knowledge Enrichment Analysis for Human Tissue- Specific Genes Uncover New Biological Insights

    Directory of Open Access Journals (Sweden)

    Gong Xiu-Jun

    2012-06-01

    Full Text Available The expression and regulation of genes in different tissues are fundamental questions to be answered in biology. Knowledge enrichment analysis for tissue specific (TS and housekeeping (HK genes may help identify their roles in biological process or diseases and gain new biological insights.In this paper, we performed the knowledge enrichment analysis for 17,343 genes in 84 human tissues using Gene Set Enrichment Analysis (GSEA and Hypergeometric Analysis (HA against three biological ontologies: Gene Ontology (GO, KEGG pathways and Disease Ontology (DO respectively.The analyses results demonstrated that the functions of most gene groups are consistent with their tissue origins. Meanwhile three interesting new associations for HK genes and the skeletal muscle tissuegenes are found. Firstly, Hypergeometric analysis against KEGG database for HK genes disclosed that three disease terms (Parkinson’s disease, Huntington’s disease, Alzheimer’s disease are intensively enriched.Secondly, Hypergeometric analysis against the KEGG database for Skeletal Muscle tissue genes shows that two cardiac diseases of “Hypertrophic cardiomyopathy (HCM” and “Arrhythmogenic right ventricular cardiomyopathy (ARVC” are heavily enriched, which are also considered as no relationship with skeletal functions.Thirdly, “Prostate cancer” is intensively enriched in Hypergeometric analysis against the disease ontology (DO for the Skeletal Muscle tissue genes, which is a much unexpected phenomenon.

  17. The future cost of uranium enrichment

    International Nuclear Information System (INIS)

    Pouris, A.

    1986-01-01

    The cost of uranium enrichment is the most important factor determining the fuel cost of nuclear energy. This paper attempts to forecast the future direction of the price of separative work by examining the forces that determine it. It is argued that the interplay among the characteristics of enrichment technologies, the structure of the international market, and the balance of supply and demand determine the enrichment price. The analysis indicates that all forces point towards a price much lower than the current one. It is predicted that, depending on the technological advances, the price of separative work unit for uranium enrichment will range between $40 and $90 by the year 2000. (author)

  18. 31 CFR 540.308 - Low Enriched Uranium (LEU).

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Low Enriched Uranium (LEU). 540.308... OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY HIGHLY ENRICHED URANIUM (HEU) AGREEMENT ASSETS CONTROL REGULATIONS General Definitions § 540.308 Low Enriched Uranium (LEU). The term low enriched...

  19. Chlorine isotope fractionation during supergene enrichment of copper

    Science.gov (United States)

    Reich, M.; Barnes, J.; Barra, F.; Milojevic, C.; Drew, D.

    2017-12-01

    Supergene enrichment of Cu deposits in the Atacama Desert has played a critical role in making this the prime Cu-producing province of the world. The Cu-hydroxychloride atacamite is a major component of supergene zones in this region whereas in similar deposits elsewhere it is rare. Atacamite requires saline water to form and dissolves rapidly when exposed to fresh, meteoric water. Previous chlorine stable isotope data [1] for atacamite mineralization at the Radomiro Tomic, Chuquicamata and Mina Sur Cu deposits show δ37Cl values that range from -0.1 to +0.2‰, indicating a similar nonmagmatic source for the introduction of chloride. However, distal atacamite mineralization on the periphery of these orebodies show more fractionated and lighter δ37Cl values (-3.2 to -0.1‰). Although little disagreement currently exists about the involvement of saline groundwater during the formation of atacamite [2], no δ37Cl data are currently available for atacamite within a single deposit and/or supergene enrichment profile that allow explaining the aforementioned differences in the observed δ37Cl values. Furthermore, no experimental data for chlorine isotope fractionation between Cu-hydroxychloride minerals and water exist that help evaluate possible mechanisms of fractionation along the groundwater flow path. Here we present a new database that combines detailed mineralogical observations with δ37Cl data of atacamite along a thick ( 100 m) supergene enrichment profile at the Barreal Seco IOCG deposit in the Atacama Desert of northern Chile. Chlorine stable isotope data of atacamite vary between -0.62 and +2.1 ‰ and show a well-defined trend where δ37Cl values progressively decrease (become lighter) with depth. These data, when combined with new experimental determinations of chlorine isotope fractionation between atacamite and water, point to changes triggered by the progressive deepening of groundwater tables during Andean uplift and the extreme desiccation of

  20. Detection of illicit HEU production in gaseous centrifuge enrichment plants using neutron counting techniques on product cylinders

    International Nuclear Information System (INIS)

    Freeman, Corey R.; Geist, William H.

    2010-01-01

    Innovative and novel safeguards approaches are needed for nuclear energy to meet global energy needs without the threat of nuclear weapons proliferation. Part of these efforts will include creating verification techniques that can monitor uranium enrichment facilities for illicit production of highly-enriched uranium (HEU). Passive nondestructive assay (NDA) techniques will be critical in preventing illicit HEU production because NDA offers the possibility of continuous and unattended monitoring capabilities with limited impact on facility operations. Gaseous centrifuge enrichment plants (GCEP) are commonly used to produce low-enriched uranium (LEU) for reactor fuel. In a GCEP, gaseous UF 6 spins at high velocities in centrifuges to separate the molecules containing 238 U from those containing the lighter 235 U. Unfortunately, the process for creating LEU is inherently the same as HEU, creating a proliferation concern. Insuring that GCEPs are producing declared enrichments poses many difficult challenges. In a GCEP, large cascade halls operating thousands of centrifuges work together to enrich the uranium which makes effective monitoring of the cascade hall economically prohibitive and invasive to plant operations. However, the enriched uranium exiting the cascade hall fills product cylinders where the UF 6 gas sublimes and condenses for easier storage and transportation. These product cylinders hold large quantities of enriched uranium, offering a strong signal for NDA measurement. Neutrons have a large penetrability through materials making their use advantageous compared to gamma techniques where the signal is easily attenuated. One proposed technique for detecting HEU production in a GCEP is using neutron coincidence counting at the product cylinder take off stations. This paper discusses findings from Monte Carlo N-Particle eXtended (MCNPX) code simulations that examine the feasibility of such a detector.

  1. Industrial aspects in uranium enrichment

    International Nuclear Information System (INIS)

    Mezin, M.

    1982-05-01

    Characteristics of isotope separation processes in operation and under development are discussed. These include the number of stages in series, the number of components, the component unit capacity and enery requirements. The implementation of an enrichment process and the question of an enrichment plant in Australia are also considered

  2. Advances in uranium enrichment processes

    International Nuclear Information System (INIS)

    Rae, H.K.; Melvin, J.G.; Slater, J.B.

    1986-05-01

    Advances in gas centrifuges and development of the atomic vapour laser isotope separation process promise substantial reductions in the cost of enriched uranium. The resulting reduction in LWR fuel costs could seriously erode the economic advantage of CANDU, and in combination with LWR design improvements, shortened construction times and increased operational reliability could allow the LWR to overtake CANDU. CANDU's traditional advantages of neutron economy and high reliability may no longer be sufficient - this is the challenge. The responses include: combining neutron economy and dollar economy by optimizing CANDU for slightly enriched uranium fuel; developing cost-reducing improvements in design, manufacture and construction; and reducing the cost of heavy water. Technology is a renewable resource which must be continually applied to a product for it to remain competitive in the decades to come. Such innovation is a prerequisite to Canada increasing her share of the international market for nuclear power stations. The higher burn-up achievable with enriched fuel in CANDU can reduce the fuel cycle costs by 20 to 40 percent for a likely range of costs for yellowcake and separative work. Alternatively, some of the benefits of a higher fissile content can take the form of a cheaper reactor core containing fewer fuel channels and less heavy water, and needing only a single fuelling machine. An opportunity that is linked to this need to introduce an enriched uranium fuel cycle into CANDU is to build an enrichment business in Canada. This could offer greater value added to our uranium exports, security of supply for enriched CANDUs, technological growth in Canada and new employment opportunities. AECL has a study in progress to define this opportunity

  3. Growth Rates of Bacillus Species Probiotics using Various Enrichment Media

    Directory of Open Access Journals (Sweden)

    Maryam Poormontaseri

    2017-03-01

    Full Text Available Background: Probiotics are well-known as valuable functional foods to promote specific health benefits to consumers. Some Bacillus bacteria have been recently considered as probiotic and food additives. We aimed to investigate the growing rate of probiotic B. subtilis and B. coagulans using several enrichment media incubated at 37 °C for 24 hours. Methods: Various enrichment media including nutrient broth (NB, tryptic soy broth (TSB, double strength TSB, Mueller Hinton broth (MH, brain-heart infusion broth (BHIB, de Man, Rogosa and Sharpe (MRS, and nutrient yeast extract salt medium (NYSM were used to enrich the probiotics and they were subsequently incubated for 18 h at 37 °C. The bacteria were then enumerated on TSA medium. Results: The results showed that B. subtilis ATCC 6633, B. subtilis PY79, and B. coagulans developed in TSB, double strength TBS, TSB yeast extract, BHIB and NYSM, respectively. Moreover, the formulas were achieved based on the optical density curve and the number of bacteria. Conclusion: Considering that the probiotics are significantly employed as food supplements, it is essential to identify appropriate enrichment media to proliferate these beneficial bacteria.

  4. Spatial occupancy models applied to atlas data show Southern Ground Hornbills strongly depend on protected areas.

    Science.gov (United States)

    Broms, Kristin M; Johnson, Devin S; Altwegg, Res; Conquest, Loveday L

    2014-03-01

    Determining the range of a species and exploring species--habitat associations are central questions in ecology and can be answered by analyzing presence--absence data. Often, both the sampling of sites and the desired area of inference involve neighboring sites; thus, positive spatial autocorrelation between these sites is expected. Using survey data for the Southern Ground Hornbill (Bucorvus leadbeateri) from the Southern African Bird Atlas Project, we compared advantages and disadvantages of three increasingly complex models for species occupancy: an occupancy model that accounted for nondetection but assumed all sites were independent, and two spatial occupancy models that accounted for both nondetection and spatial autocorrelation. We modeled the spatial autocorrelation with an intrinsic conditional autoregressive (ICAR) model and with a restricted spatial regression (RSR) model. Both spatial models can readily be applied to any other gridded, presence--absence data set using a newly introduced R package. The RSR model provided the best inference and was able to capture small-scale variation that the other models did not. It showed that ground hornbills are strongly dependent on protected areas in the north of their South African range, but less so further south. The ICAR models did not capture any spatial autocorrelation in the data, and they took an order, of magnitude longer than the RSR models to run. Thus, the RSR occupancy model appears to be an attractive choice for modeling occurrences at large spatial domains, while accounting for imperfect detection and spatial autocorrelation.

  5. Bulk enrichment of transplantable hemopoietic stem cell subsets from lipopolysaccharide-stimulated murine spleen

    International Nuclear Information System (INIS)

    Ploemacher, R.E.; Brons, R.H.; Leenen, P.J.

    1987-01-01

    Counterflow centrifugal elutriation (CCE) in combination with density flotation centrifugation and fluorescence-activated cell sorting on wheat-germ agglutinin-FITC(WGA)-binding cells within the light-scatter ''blast window'' were used consecutively to enrich pluripotent hemopoietic stem cells (HSC) in bulk from lipopolysaccharide-stimulated mouse spleen. The medium-to-strong WGA + ve fraction contained 3.10(6) cells isolated from 3-4 X 10(9) spleen cells, with an average of 126% day-12 CFU-S and 65% day-8 CFU-S as calculated on the basis of their seeding fraction, suggesting that virtually all cells represented in vivo macroscopic colony formers. In view of the large differences reported elsewhere between stem cell subsets differing in reconstitutive capacity and secondary stem cell generation ability, we also studied various isolated cell fractions with respect to spleen colony formation, radioprotective ability, and spleen- and marrow- repopulating ability. Day-8 and day-12 CFU-S copurified when isolated by CCE. Cells from a fraction with high affinity for WGA were most highly enriched for their radioprotective ability (RPA) and their ability to repopulate the cellularity of the spleen and femur of irradiated recipients. This fraction contained virtually pure day-12 CFU-S. However, the ability to generate secondary day-12 CFU-S and CFU-GM in irradiated organs was enriched most in the medium WGA + ve cell fraction. MRA and SRA, according to the latter criteria, could therefore be partly separated from day-12 CFU-S and RPA on the basis of affinity for WGA. The data strongly suggest that at least part of all day-12 CFU-S have a high potential to proliferate and differentiate into mature progeny, but a relatively low self-renewal ability, and may therefore not be representative of the genuine stem cell

  6. Environmental enrichment for aquatic animals.

    Science.gov (United States)

    Corcoran, Mike

    2015-05-01

    Aquatic animals are the most popular pets in the United States based on the number of owned pets. They are popular display animals and are increasingly used in research settings. Enrichment of captive animals is an important element of zoo and laboratory medicine. The importance of enrichment for aquatic animals has been slower in implementation. For a long time, there was debate over whether or not fish were able to experience pain or form long-term memories. As that debate has reduced and the consciousness of more aquatic animals is accepted, the need to discuss enrichment for these animals has increased. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. The density of GM1-enriched lipid rafts correlates inversely with the efficiency of transfection mediated by cationic liposomes.

    Science.gov (United States)

    Kovács, Tamás; Kárász, Andrea; Szöllosi, János; Nagy, Peter

    2009-08-01

    Although cationic liposome-mediated transfection has become a standard procedure, the mechanistic details of the process are unknown. It has been suggested that endocytic uptake of lipoplexes is efficient, and transfectability is largely determined by later steps. In this article, we stained GM1-enriched membrane microdomains, a subclass of lipid rafts, with subunit B of cholera toxin and correlated transfection efficiency with their density by quantitatively evaluating microscopic images. We found a strong anticorrelation between the density of GM1-enriched membrane microdomains and the efficacy of transfection monitored by measuring the expression level of GFP in different cell lines transfected by lipofection using two different transfection agents. These findings imply that GM1-enriched membrane microdomains interfere with the process of lipofection. The blocked step must be endocytosis since the accumulation of fluorescently labeled plasmids was lower in cells with high content of GM1-enriched membrane microdomains. Such a correlation was not observed in cells transfected by electroporation. By comparing the efficiency of lipofection in several cell lines we found that those with a high density of GM1-enriched membrane microdomains were the most resistant to transfection. We conclude that the inhibition of lipofection by GM1-enriched membrane microdomains is a general rule, and that endocytosis of lipoplexes can be rate limiting in cells with high density of GM1-enriched membrane rafts. Copyright 2009 International Society for Advancement of Cytometry.

  8. The impact of early postnatal environmental enrichment on maternal care and offspring behaviour following weaning.

    Science.gov (United States)

    Li, Ki Angel; Lund, Emilie Torp; Voigt, Jörg-Peter W

    2016-01-01

    The early postnatal period is a sensitive period in rodents as behavioural systems are developing and maturing during this time. However, relatively little information is available about the impact of environmental enrichment on offspring behaviour if enrichment is implemented only during this period. Here, environmental enrichment was provided from postnatal day 1 until weaning. On post-natal day 9, maternal behaviour and nonmaternal behaviour of the dam was observed. Nursing time in the enriched group was reduced but dams showed more non-maternal appetitive behaviours. Offspring were exposed to either the open field or the elevated plus maze (EPM) after weaning. In the open field, rats from the enriched group approached the more aversive inner zone of the open field later than control rats. Offspring from the enriched group made fewer entries into the inner zone and spent less time in this part of the arena. Enrichment had no impact on behaviour in the EPM. The present study provides evidence that postnatal enrichment can interfere with maternal behaviour in rats and can possibly lead to increased anxiety in the offspring. The findings suggest that enrichment procedures can have potentially unintended effects, interfering with the development of emotional behaviours in rats. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Anaerobic degradation of propane and butane by sulfate-reducing bacteria enriched from marine hydrocarbon cold seeps.

    Science.gov (United States)

    Jaekel, Ulrike; Musat, Niculina; Adam, Birgit; Kuypers, Marcel; Grundmann, Olav; Musat, Florin

    2013-05-01

    The short-chain, non-methane hydrocarbons propane and butane can contribute significantly to the carbon and sulfur cycles in marine environments affected by oil or natural gas seepage. In the present study, we enriched and identified novel propane and butane-degrading sulfate reducers from marine oil and gas cold seeps in the Gulf of Mexico and Hydrate Ridge. The enrichment cultures obtained were able to degrade simultaneously propane and butane, but not other gaseous alkanes. They were cold-adapted, showing highest sulfate-reduction rates between 16 and 20 °C. Analysis of 16S rRNA gene libraries, followed by whole-cell hybridizations with sequence-specific oligonucleotide probes showed that each enrichment culture was dominated by a unique phylotype affiliated with the Desulfosarcina-Desulfococcus cluster within the Deltaproteobacteria. These phylotypes formed a distinct phylogenetic cluster of propane and butane degraders, including sequences from environments associated with hydrocarbon seeps. Incubations with (13)C-labeled substrates, hybridizations with sequence-specific probes and nanoSIMS analyses showed that cells of the dominant phylotypes were the first to become enriched in (13)C, demonstrating that they were directly involved in hydrocarbon degradation. Furthermore, using the nanoSIMS data, carbon assimilation rates were calculated for the dominant cells in each enrichment culture.

  10. Review of uranium enrichment prospects in Canada, 1976

    International Nuclear Information System (INIS)

    Developments since 1971 which affect the prospects for uranium enrichment in Canada from the federal government point of view are reviewed. The market for enriched uranium to the year 2000 is similar to that projected in 1971. The committed enrichment capacity of the world will be sufficient until 1990. The Canadian uranium mining capability may be adequate to supply an enrichment plant, but the present reserves policy along with the currently known resources are likely to restrict exports of its products during the plant life. Prices for enriched uranium produced in Canada would be higher than those reported by other proposed new plants; however, newer enrichment techniques have some potential for cost reductions. Application of enrichment with U235 (or plutonium and U233/thorium) to CANDU offers some uranium resource conservation and possible slight power cost reductions. Construction of an enrichment plant in Canada to supply the export market is less attractive in 1976 than in 1971, but there is potential for such a business in the future. (L.L.)

  11. Influence of enriched soaking water on shiitake (Lentinus edodes (Berk. Singer mushroom yield and properties

    Directory of Open Access Journals (Sweden)

    Mohammad Ebrahim RANJBAR

    2017-12-01

    Full Text Available Shiitake is an edible mushroom native to East Asia. In the present research, the soaking water was targeted as the vehicle to enrich the substrate. The amount of nutrients in the substrate is severely reduced by mycelium growth and development during spawn running and browning period. Some part of this reduction can be compensated by soaking the substrate in the enriched soaking water. In this study, soaking water was enriched by some complement materials and enrichment effects on some important properties of shiitake mushroom were evaluated. The highest biological efficiency (69.88 % was gained with soaking the blocks in wheat bran extraction suspension. The highest dry matter of mushroom was obtained by rice bran extraction suspension as the enriched soaking water. The results of this research showed that some important properties of shiitake mushroom can be improved by soaking the blocks with enriched soaking water. According to the results, wheat bran extraction suspension was the best enriched solution to increase productivity of shiitake mushrooms and rice bran extraction suspension was suitable to improve quality of mushrooms.

  12. Lead enrichment in different genotypes of rice grains.

    Science.gov (United States)

    Chen, Gang; Sun, Guo-rong; Liu, Ai-ping; Zhou, Wei-dong

    2008-03-01

    Using environmental scanning electron microscopy and X-ray electron probe microanalysis, the lead content was studied in inner and outer surface of rice glume, surface of caryopsis, center of caryopsis, near aleuronic layer and aleuronic layer in 21 genotypes of rice grains. The results showed that the lead content in different part of 21 genotypes of rice grains changed as inner surface of rice glume > aleuronic layer > near aleuronic layer > surface of caryopsis > outer surface of rice glume > center of caryopsis. There were genetic differences in lead enrichment in different genotypes of rice grains, which reflected as the differences of lead content in the same part and different part of rice grains. In different genotypes of rice grains, there were significant non-linear correlations between lead content in the inner surface of rice glume, center of caryopsis, aleuronic layer and that in the other parts of rice grain. The results also indicated that the lead enrichment in the center of caryopsis regulated by glume and aleuronic layer. In addition, in different genotypes of rice grains, there were differences in regulation of lead enrichment among different parts, which changed non-linearly.

  13. Mung bean nuclease treatment increases capture specificity of microdroplet-PCR based targeted DNA enrichment.

    Directory of Open Access Journals (Sweden)

    Zhenming Yu

    Full Text Available Targeted DNA enrichment coupled with next generation sequencing has been increasingly used for interrogation of select sub-genomic regions at high depth of coverage in a cost effective manner. Specificity measured by on-target efficiency is a key performance metric for target enrichment. Non-specific capture leads to off-target reads, resulting in waste of sequencing throughput on irrelevant regions. Microdroplet-PCR allows simultaneous amplification of up to thousands of regions in the genome and is among the most commonly used strategies for target enrichment. Here we show that carryover of single-stranded template genomic DNA from microdroplet-PCR constitutes a major contributing factor for off-target reads in the resultant libraries. Moreover, treatment of microdroplet-PCR enrichment products with a nuclease specific to single-stranded DNA alleviates off-target load and improves enrichment specificity. We propose that nuclease treatment of enrichment products should be incorporated in the workflow of targeted sequencing using microdroplet-PCR for target capture. These findings may have a broad impact on other PCR based applications for which removal of template DNA is beneficial.

  14. Enrichment of Acinetobacter spp. from food samples.

    Science.gov (United States)

    Carvalheira, Ana; Ferreira, Vânia; Silva, Joana; Teixeira, Paula

    2016-05-01

    Relatively little is known about the role of foods in the chain of transmission of acinetobacters and the occurrence of different Acinetobacter spp. in foods. Currently, there is no standard procedure to recover acinetobacters from food in order to gain insight into the food-related ecology and epidemiology of acinetobacters. This study aimed to assess whether enrichment in Dijkshoorn enrichment medium followed by plating in CHROMagar™ Acinetobacter medium is a useful method for the isolation of Acinetobacter spp. from foods. Recovery of six Acinetobacter species from food spiked with these organisms was compared for two selective enrichment media (Baumann's enrichment and Dijkshoorn's enrichment). Significantly (p enrichment. Next, the Dijkshoorn's enrichment followed by direct plating on CHROMagar™ Acinetobacter was applied to detect Acinetobacter spp. in different foods. Fourteen different presumptive acinetobacters were recovered and assumed to represent nine different strains on the basis of REP-PCR typing. Eight of these strains were identified by rpoB gene analysis as belonging to the species Acinetobacter johnsonii, Acinetobacter calcoaceticus, Acinetobacter guillouiae and Acinetobacter gandensis. It was not possible to identify the species level of one strain which may suggests that it represents a distinct species. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Enrichment of sub-milligram size carbon samples

    NARCIS (Netherlands)

    Kitagawa, H; vanderPlicht, J

    We have developed a carbon isotope enrichment system for use in conjunction with the Groningen Accelerator Mass Spectrometer. Using thermal diffusion of CO, we obtained an enrichment factor of about 3 for C-13 for half-gram carbon in 5 days. This means we expect for C-14 an enrichment factor of 6,

  16. An enriched multimedia eBook application to facilitate learning of anatomy.

    Science.gov (United States)

    Stirling, Allan; Birt, James

    2014-01-01

    This pilot study compared the use of an enriched multimedia eBook with traditional methods for teaching the gross anatomy of the heart and great vessels. Seventy-one first-year students from an Australian medical school participated in the study. Students' abilities were examined by pretest, intervention, and post-test measurements. Perceptions and attitudes toward eBook technology were examined by survey questions. Results indicated a strongly positive user experience coupled with increased marks; however, there were no statistically significant results for the eBook method of delivery alone outperforming the traditional anatomy practical session. Results did show a statistically significant difference in the final marks achieved based on the sequencing of the learning modalities. With initial interaction with the multimedia content followed by active experimentation in the anatomy lab, students' performance was improved in the final test. Obtained data support the role of eBook technology in modern anatomy curriculum being a useful adjunct to traditional methods. Further study is needed to investigate the importance of sequencing of teaching interventions. © 2013 American Association of Anatomists.

  17. Review of environmental enrichment for broiler chickens

    DEFF Research Database (Denmark)

    Riber, Anja Brinch; Van de Weerd, H.A.; de Jong, I.C.

    2018-01-01

    to improvements of the biological function. This definition has been broadened to include practical and economic aspects, as any enrichment strategy that adversely affects the health of animals or that has too many economic or practical constraints will never be implemented on commercial farms and thus never...... benefit animals. Environmental enrichment for broilers often has the purpose of satisfying behavioral needs and/or stimulating the broilers to an increased level of activity, which among others will reduce the occurrence of leg problems. Potentially successful environmental enrichments for broiler...... chickens are elevated resting-places, panels, barriers, and bales of straw (“point-source enrichment”), as well as covered verandas and outdoor ranges (“complex enriched environments”). Many of the ideas for environmental enrichment for broilers need to be further developed and studied, preferably...

  18. Current perspective of the uranium enrichment market

    International Nuclear Information System (INIS)

    Laughon, K.O.

    1986-01-01

    Over the past several years, developments in the uranium enrichment market have required the Department of Energy (DOE) to make a number of changes in the U.S. enrichment enterprise. These changes have been made to allow DOE to conduct our enrichment business so as to be more responsive to changing market forces. Needless to say, some of these changes have been difficult, but they have been necessary if they are to conduct a healthy and competitive uranium enrichment business in the United States. This paper discusses several topics, including: The Uranium Enrichment Market, Utility Services (US) Contracts, Reduced Prices, Incentive Pricing, Better Customer Services, and Advanced Technology. In addition to these topics, information is provided on the recent court action regarding the US Contracts and the viability finding on the uranium mining industry

  19. Nanopore density effect of polyacrylamide gel plug on electrokinetic ion enrichment in a micro-nanofluidic chip

    Science.gov (United States)

    Wang, Jun-yao; Xu, Zheng; Li, Yong-kui; Liu, Chong; Liu, Jun-shan; Chen, Li; Du, Li-qun; Wang, Li-ding

    2013-07-01

    In this paper, the nanopore density effect on ion enrichment is quantitatively described with the ratio between electrophoresis flux and electroosmotic flow flux based on the Poisson-Nernst-Planck equations. A polyacrylamide gel plug is integrated into a microchannel to form a micro-nanofluidic chip. With the chip, electrokinetic ion enrichment is relatively stable and enrichment ratio of fluorescein isothiocyanate can increase to 600-fold within 120 s at the electric voltage of 300 V. Both theoretical research and experiments show that enrichment ratio can be improved through increasing nanopore density. The result will be beneficial to the design of micro-nanofluidic chips.

  20. Review of environmental enrichment for broiler chickens.

    Science.gov (United States)

    Riber, A B; van de Weerd, H A; de Jong, I C; Steenfeldt, S

    2018-02-01

    Welfare problems are commonly found in both conventional and organic production of broiler chickens. In order to reduce the extent of welfare problems, it has been suggested to provide stimulating, enriched environments. The aim of the present paper is to provide a review of the effect on behavior and welfare of the different kinds of environmental enrichments in the production of broilers that have been described in the scientific literature. Environmental enrichment is defined as an improvement of the environment of captive animals, which increases the behavioral opportunities of the animal and leads to improvements of the biological function. This definition has been broadened to include practical and economic aspects, as any enrichment strategy that adversely affects the health of animals or that has too many economic or practical constraints will never be implemented on commercial farms and thus never benefit animals. Environmental enrichment for broilers often has the purpose of satisfying behavioral needs and/or stimulating the broilers to an increased level of activity, which among others will reduce the occurrence of leg problems. Potentially successful environmental enrichments for broiler chickens are elevated resting-places, panels, barriers, and bales of straw ("point-source enrichment"), as well as covered verandas and outdoor ranges ("complex enriched environments"). Many of the ideas for environmental enrichment for broilers need to be further developed and studied, preferably in commercial trials, with respect to the use, the effect on behavior and on other welfare aspects such as leg health, and the interaction with genotype, production system, stocking density, light, and flock size. In addition, information on the practical application and the economics of the production system is often lacking, although it is important for application in practice. © 2017 Poultry Science Association Inc.

  1. Protein enriched pasta: structure and digestibility of its protein network.

    Science.gov (United States)

    Laleg, Karima; Barron, Cécile; Santé-Lhoutellier, Véronique; Walrand, Stéphane; Micard, Valérie

    2016-02-01

    Wheat (W) pasta was enriched in 6% gluten (G), 35% faba (F) or 5% egg (E) to increase its protein content (13% to 17%). The impact of the enrichment on the multiscale structure of the pasta and on in vitro protein digestibility was studied. Increasing the protein content (W- vs. G-pasta) strengthened pasta structure at molecular and macroscopic scales but reduced its protein digestibility by 3% by forming a higher covalently linked protein network. Greater changes in the macroscopic and molecular structure of the pasta were obtained by varying the nature of protein used for enrichment. Proteins in G- and E-pasta were highly covalently linked (28-32%) resulting in a strong pasta structure. Conversely, F-protein (98% SDS-soluble) altered the pasta structure by diluting gluten and formed a weak protein network (18% covalent link). As a result, protein digestibility in F-pasta was significantly higher (46%) than in E- (44%) and G-pasta (39%). The effect of low (55 °C, LT) vs. very high temperature (90 °C, VHT) drying on the protein network structure and digestibility was shown to cause greater molecular changes than pasta formulation. Whatever the pasta, a general strengthening of its structure, a 33% to 47% increase in covalently linked proteins and a higher β-sheet structure were observed. However, these structural differences were evened out after the pasta was cooked, resulting in identical protein digestibility in LT and VHT pasta. Even after VHT drying, F-pasta had the best amino acid profile with the highest protein digestibility, proof of its nutritional interest.

  2. Balts show strong notes in Grammy Awards

    Index Scriptorium Estoniae

    2005-01-01

    Los Angeleses 8. veebr. Grammy Awards nominantide seas läti laulja Elina Garanca, dirigendid Paavo Järvi (Schumann "Cello Concerto" and Bloch's "Schelomo") ja Maris Jansons. Eelmisel aastal pälvis Grammy teos Sibelius "Cantatas" (esitajad Ellerheina tütarlastekoor Ester Loitme juhatusel, Eesti Rahvusmeeskoor, ERSO, dirigendid Ants Soots ja Paavo Järvi)

  3. Fresh pasta production enriched with Spirulina platensis biomass

    Directory of Open Access Journals (Sweden)

    Ailton Cesar Lemes

    2012-10-01

    Full Text Available The aim of this work was to study the enrichment of Spirulina platensis in wheat flour to prepare fresh pasta to evaluate the green color and nutritional enrichment in addition to functional properties due to the presence of the bioactive compounds in the cyanobacterium. The pastas were evaluated for the centesimal composition, microbiological contamination, sensorial acceptance and technological characteristics such as cooking time, water absorption, volume displacement and loss of solids. The superior protein contents and the satisfactory technological and sensorial attributes compared with the control with no cyanobacterium showed the usefulness of incorporating S. platensis biomass in the fresh pastas. The microbiological quality was in compliance with the legislation in force. The sensorial quality was considered satisfactory (“liked very much” and purchase intention high (“probably would buy”.

  4. Temperature coefficients in the Dragon low-enriched power reactor

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, U

    1972-05-15

    The temperature coefficient of the fuel and of the moderator have been evaluated for the Dragon HTR design for different stages in reactor life, initial core, end of no-refuelling period and equilibrium conditions. The investigation has shown the low-enriched HTR to have a strong, positive moderator coefficient. In some cases and for special operating conditions, even leading to a positive total temperature coefficient. This does not imply, however, that the HTR is an unsafe reactor system. By adequate design of the control system, safe and reliable operating characteristics can be achieved. This has already been proved satisfactory through many years of operation of other graphite moderated systems, such as the Magnox stations.

  5. Comparative proteomic assessment of matrisome enrichment methodologies

    Science.gov (United States)

    Krasny, Lukas; Paul, Angela; Wai, Patty; Howard, Beatrice A.; Natrajan, Rachael C.; Huang, Paul H.

    2016-01-01

    The matrisome is a complex and heterogeneous collection of extracellular matrix (ECM) and ECM-associated proteins that play important roles in tissue development and homeostasis. While several strategies for matrisome enrichment have been developed, it is currently unknown how the performance of these different methodologies compares in the proteomic identification of matrisome components across multiple tissue types. In the present study, we perform a comparative proteomic assessment of two widely used decellularisation protocols and two extraction methods to characterise the matrisome in four murine organs (heart, mammary gland, lung and liver). We undertook a systematic evaluation of the performance of the individual methods on protein yield, matrisome enrichment capability and the ability to isolate core matrisome and matrisome-associated components. Our data find that sodium dodecyl sulphate (SDS) decellularisation leads to the highest matrisome enrichment efficiency, while the extraction protocol that comprises chemical and trypsin digestion of the ECM fraction consistently identifies the highest number of matrisomal proteins across all types of tissue examined. Matrisome enrichment had a clear benefit over non-enriched tissue for the comprehensive identification of matrisomal components in murine liver and heart. Strikingly, we find that all four matrisome enrichment methods led to significant losses in the soluble matrisome-associated proteins across all organs. Our findings highlight the multiple factors (including tissue type, matrisome class of interest and desired enrichment purity) that influence the choice of enrichment methodology, and we anticipate that these data will serve as a useful guide for the design of future proteomic studies of the matrisome. PMID:27589945

  6. Enrichment technology. Dependable vendor of gas centrifuges

    International Nuclear Information System (INIS)

    Anon.

    2011-01-01

    Enrichment Technology is an innovative, high-tech company that develops, manufactures and installs gas centrifuges for enriching uranium. In addition, Enrichment Technology designs enrichment plants that use gas centrifuge technology. This technology offers the most efficient and cost-effective method for enriching uranium yet: high-performance, safe technology that dominates the market with a global share of 45 percent. A determining factor in Enrichment Technology's success is its mission: supplying its customers with safe, reliable technology. Production of the centrifuges requires versatile know-how and collaboration between different departments as well as interdisciplinary teams at the various sites. More than 2000 operators at 8 sites in 5 countries contribute their individual knowledge and personal skills in order to produce this exceptional technology. The head office is in Beaconsfield near London and the operational headquarters are in Almelo in the Netherlands. There are other sites in Germany (Juelich und Gronau), Great Britain (Capenhurst) as well as project sites in the USA and France. Capenhurst is where experienced engineers design new enrichment plants and organise their construction. Centrifuge components are manufactured in Almelo and Juelich, while the pipework needed to connect up the centrifuges is produced at the site in Gronau. In Juelich, highly qualified scientists in interdisciplinary teams are continuously researching ways of improving the current centrifuges. Communication between specialists in the fields of chemistry, physics and engineering forms the basis for the company's success and the key to extending this leading position in the global enrichment market. (orig.)

  7. Comments on applications of reduced enrichment fuels

    International Nuclear Information System (INIS)

    Winkler, M.H.

    1983-01-01

    Full text: I will briefly describe the experience gained using different fuels in the SAPHIR reactor in Switzerland. The SAPHIR has been operating since 1957 and was the first swimming pool reactor built outside of the United States, which was originally known as the Geneva Conference Reactor. The first core was loaded with 20 percent enriched high density UO 2 fuel with a density of about 2.5 grams per cc, fabricated in 1955 by Oak Ridge National Laboratory. After a few years of operation at a power level of one MW, more than one batch of the elements released small amounts of fission products mainly Xe and Kr. When these releases were discovered, high enriched fuel was becoming available so that the fuel fabricators began to produce the lower density high enriched fuels. During this transition from fabrication of low to high enriched fuels no one could foresee that the stone age of nuclear fuel fabrication would come back again. Therefore, we did not investigate the reasons for the fission product release from the high density low enriched UO 2 fuel. The second fuel type used in the SAPHIR was the 90 percent enriched low density U 3 O 8 fuel fabricated by NUKEM. This high enriched fuel has performed satisfactorily over the years. Since 1968, the core has been using improved 23 plate fuel elements with a loading of 280 grams of uranium. The reactor power has been recently increased to five MW. An additional increase in the power level to 10 MW is planned at the end of next year so that heavier loaded elements will be needed. In order to follow the recommendations of the INFCE working group 8C and in cooperation with the reduced enrichment program, we intend to initially reduce the fuel enrichment to 45 percent. Last year we ordered five fuel elements with a loading of 320 grams 235 U/element and 45 percent enrichment for full power tests. Unfortunately, the delivery of the necessary enriched fuel uranium has been delayed and it is not available at this time. If

  8. Effect of substrate intake and physiological state on background 13CO2 enrichment

    International Nuclear Information System (INIS)

    Wolfe, R.R.; Shaw, J.H.F.; Nadel, E.R.; Wolfe, M.H.

    1984-01-01

    The natural enrichment of 13 C in energy substrates varies, and this variation must be taken into account when stable isotopic tracers are used in metabolic studies. This is conventionally accomplished by measuring background samples taken before the tracer infusion begins and subtracting these values from postinfusion values. Whereas this approach is satisfactory if no perturbation occurs between the collection of the background samples and the collection of postinfusion sample, the data presented in this paper show that any change in the metabolic state can significantly alter the background enrichment of expired CO 2 . This study not only confirmed that the introduction of natural energy sources may alter the background enrichment of CO 2 , but we also found that changes in substrate oxidation induced by different physiological states, such as exercise, can cause significant changes in expired CO 2 enrichments. Conclusions from studies in which oxidation of substrates were measured by means of a 13 C tracer but potential changes in background enrichments were not accounted for must, therefore, be reassessed

  9. Continuous monitoring of variations in the 235U enrichment of uranium in the header pipework of a centrifuge enrichment plant

    International Nuclear Information System (INIS)

    Packer, T.W.

    1991-01-01

    Non-destructive assay equipment, based on gamma-ray spectrometry and x-ray fluorescence analysis has previously been developed for confirming the presence of low enriched uranium in the header pipework of UF 6 gas centrifuge enrichment plants. However inspections can only be carried out occasionally on a limited number of pipes. With the development of centrifuge enrichment technology it has been suggested that more frequent, or ideally, continuous measurements should be made in order to improve safeguards assurance between inspections. For this purpose we have developed non-destructive assay equipment based on continuous gamma-ray spectrometry and x-ray transmission measurements. This equipment is suitable for detecting significant changes in the 235 U enrichment of uranium in the header pipework of new centrifuge enrichment plants. Results are given in this paper of continuous measurements made in the laboratory and also on header pipework of a centrifuge enrichment plant at Capenhurst

  10. Enriched environment reduces apolipoprotein E (ApoE) in reactive astrocytes and attenuates inflammation of the peri-infarct tissue after experimental stroke

    DEFF Research Database (Denmark)

    Ruscher, Karsten; Johannesson, Emelie; Brugiere, Elena

    2009-01-01

    Apolipoprotein E (ApoE), a cholesterol transporter and an immunomodulator, is brain protective after experimental stroke and implicated in brain repair. Here, we study the involvement of ApoE in the restoration of brain function after experimental stroke, by using animal housing conditions...... lower in animals housed in an enriched environment. We propose that during the subacute phase after experimental stroke a zone for tissue reorganization with low cellular ApoE levels is formed. We conclude that the strong sensori-motor stimulation provided by enriched housing conditions mitigates...

  11. Effects of Environmental Enrichment on the Fertility and Fecundity of Zebrafish (Danio rerio).

    Science.gov (United States)

    Wafer, Lemnique N; Jensen, V Behrana; Whitney, Jesse C; Gomez, Thomas H; Flores, Rene; Goodwin, Bradford S

    2016-01-01

    Zebrafish (Danio rerio) are a popular vertebrate model in biomedical research, but information describing the effects of environmental enrichment on fertility and fecundity of zebrafish is sparse. In the current study, 18 breeding pairs were placed in divided 1.5-L breeding tanks containing 1 of 3 enrichment conditions: plastic grass (n = 6), plastic leaves (n = 6), or no enrichment (n = 6, control). The pairs were allowed to spawn for 3 h the next day, after which eggs were counted and breeding pairs were returned to holding tanks for use in subsequent sessions. Spawning sessions were repeated at 7-d intervals until the completion of 9 trials, with pairs rotating to a different condition at each interval. Total egg count (mean ± SEM) after 3 h was greater for zebrafish spawning in the grass environment (48.0 ± 7.7 eggs) than in the leaf or control environments (29.4 ± 5.3 and 20.4 ± 3.7 eggs, respectively). An interaction emerged between enrichment type and the age of the spawning pair on the number of fry at 6 d postfertilization (dpf). Initially, more fry were obtained from 110- and 160-dpf pairs with the grass enrichment, but from 173- and 180-dpf pairs there were more obtained with leaf enrichment than grass. A separate experiment showed that enrichment type did not have an effect on fry survivability. Overall, our data indicates that, under certain conditions, zebrafish fertility and fecundity are greater in a breeding tank containing environmental enrichment than in a bare tank.

  12. Multinational uranium enrichment in the Middle East

    International Nuclear Information System (INIS)

    Ahmad, Ali; Salahieh, Sidra; Snyder, Ryan

    2017-01-01

    The Joint Comprehensive Plan of Action (JCPOA) agreed to by Iran and the P5+1 in July 2015 placed restrictions on Iran’s nuclear program while other Middle Eastern countries– Egypt, Jordan, Saudi Arabia, Turkey, and the United Arab Emirates–are planning to build their own nuclear power plants to meet increasing electricity demands. Although the JCPOA restricts Iran's uranium enrichment program for 10–15 years, Iran's neighbors may choose to develop their own national enrichment programs giving them a potential nuclear weapons capability. This paper argues that converting Iran's national enrichment program to a more proliferation-resistant multinational arrangement could offer significant economic benefits–reduced capital and operational costs–due to economies of scale and the utilization of more efficient enrichment technologies. In addition, the paper examines policy aspects related to financing, governance, and how multinational enrichment could fit into the political and security context of the Middle East. A multinational enrichment facility managed by regional and international partners would provide more assurance that it remains peaceful and could help build confidence between Iran and its neighbors to cooperate in managing other regional security challenges. - Highlights: • Freezing Iran's nuclear program is an opportunity to launch joint initiatives in ME. • A joint uranium enrichment program in the Middle East offers economic benefits. • Other benefits include improved nuclear security and transparency in the region.

  13. Reduced Enrichment for Research and Test Reactors. Proceedings of the XVIII international meeting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    Almost 50 papers presented were showing the status of the national programs related to conversion of research reactor cores from highly enriched (HEU) to low enriched uranium (LEU) fuel elements. Design of new fuel elements (uranium silicides) and safety related calculations were dealt with taking into account fuel cycle issues, meaning spent fuel storage and transportation. A number of presentations were devoted to Mo-99 production using LEU targets.

  14. Reduced Enrichment for Research and Test Reactors. Proceedings of the XVIII international meeting

    International Nuclear Information System (INIS)

    2004-01-01

    Almost 50 papers presented were showing the status of the national programs related to conversion of research reactor cores from highly enriched (HEU) to low enriched uranium (LEU) fuel elements. Design of new fuel elements (uranium silicides) and safety related calculations were dealt with taking into account fuel cycle issues, meaning spent fuel storage and transportation. A number of presentations were devoted to Mo-99 production using LEU targets

  15. Enriching semantic knowledge bases for opinion mining in big data applications.

    Science.gov (United States)

    Weichselbraun, A; Gindl, S; Scharl, A

    2014-10-01

    This paper presents a novel method for contextualizing and enriching large semantic knowledge bases for opinion mining with a focus on Web intelligence platforms and other high-throughput big data applications. The method is not only applicable to traditional sentiment lexicons, but also to more comprehensive, multi-dimensional affective resources such as SenticNet. It comprises the following steps: (i) identify ambiguous sentiment terms, (ii) provide context information extracted from a domain-specific training corpus, and (iii) ground this contextual information to structured background knowledge sources such as ConceptNet and WordNet. A quantitative evaluation shows a significant improvement when using an enriched version of SenticNet for polarity classification. Crowdsourced gold standard data in conjunction with a qualitative evaluation sheds light on the strengths and weaknesses of the concept grounding, and on the quality of the enrichment process.

  16. 21 CFR 137.260 - Enriched corn meals.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Enriched corn meals. 137.260 Section 137.260 Food... Flours and Related Products § 137.260 Enriched corn meals. (a) Enriched corn meals are the foods, each of which conforms to the definition and standard of identity prescribed for a kind of corn meal by §§ 137...

  17. How enrichment affects exploration trade-offs in rats: implications for welfare and well-being.

    Directory of Open Access Journals (Sweden)

    Becca Franks

    Full Text Available We propose that a comparative approach to well-being could be the key to understanding 'the good life.' Inspired by current theories of human well-being and animal welfare, we designed a novel test of exploration behavior. Environmentally and socially enriched Long-Evans female rats (N = 60 were trained in four simultaneously presented arms of an eight-arm radial-maze. They learned to expect successes in two arms and failures in the other two. After training, 20 animals remained in enriched housing (enrichment-maintenance while 40 animals were re-housed in standard, isolated conditions (enrichment-removal. Two weeks later, all animals were re-tested in the maze, initially with access to the four familiar arms only. In the final minute, they also had access to the unfamiliar ambiguous-arms. Though both groups showed significant interest in the ambiguous-arms (P.3. Thus, we show not only that rats will abandon known rewards and incur risk in order to explore, indicating that exploration is valuable in its own right, but also that individuals with (vs. without enriched housing conditions are more likely to engage in such exploratory behavior. This novel test contributes to the body of knowledge examining the importance of exploration in humans and other animals; implications for animal welfare and human well-being are discussed.

  18. Showing no spot sign is a strong predictor of independent living after intracerebral haemorrhage

    DEFF Research Database (Denmark)

    Havsteen, Inger; Ovesen, Christian; Christensen, Anders F

    2014-01-01

    BACKGROUND: A spot sign on computed tomography angiography (CTA) is a potentially strong predictor of poor outcome on ultra-early radiological imaging. The aim of this study was to assess the spot sign as a predictor of functional outcome at 3 months as well as long-term mortality, with a focus...... on the ability to identify patients with a spontaneous, acceptable outcome. METHODS: In a prospective, consecutive single-centre registry of acute stroke patients, we investigated patients with spontaneous intracerebral haemorrhage (ICH) admitted within 4.5 h after symptom onset from April 2009 to January 2013....... The standard work-up in our centre included CTA for spot sign status, unless a contraindication was present. Modified Rankin Scale (mRS) scores were assessed at 3 months in the outpatient clinic or by telephone interviews. Long-term mortality was assessed by electronic chart follow-up for up to 1,500 days...

  19. PC based uranium enrichment analyser

    International Nuclear Information System (INIS)

    Madan, V.K.; Gopalakrishana, K.R.; Bairi, B.R.

    1991-01-01

    It is important to measure enrichment of unirradiated nuclear fuel elements during production as a quality control measure. An IBM PC based system has recently been tested for enrichment measurements for Nuclear Fuel Complex (NFC), Hyderabad. As required by NFC, the system has ease of calibration. It is easy to switch the system from measuring enrichment of fuel elements to pellets and also automatically store the data and the results. The system uses an IBM PC plug in card to acquire data. The card incorporates programmable interval timers (8253-5). The counter/timer devices are executed by I/O mapped I/O's. A novel algorithm has been incorporated to make the system more reliable. The application software has been written in BASIC. (author). 9 refs., 1 fig

  20. Performance evaluation of nanoclay enriched anti-microbial hydrogels for biomedical applications

    Directory of Open Access Journals (Sweden)

    Sonali Karnik

    2016-02-01

    Full Text Available A major factor contributing to the failure of orthopedic and orthodontic implants is post-surgical infection. Coating metallic implant surfaces with anti-microbial agents has shown promise but does not always prevent the formation of bacterial biofilms. Furthermore, breakdown of these coatings within the human body can cause release of the anti-microbial drugs in an uncontrolled or unpredictable fashion. In this study, we used a calcium alginate and calcium phosphate cement (CPC hydrogel composite as the base material and enriched these hydrogels with the anti-microbial drug, gentamicin sulfate, loaded within a halloysite nanotubes (HNTs. Our results demonstrate a sustained and extended release of gentamicin from hydrogels enriched with the gentamicin-loaded HNTs. When tested against the gram-negative bacteria, the hydrogel/nanoclay composites showed a pronounced zone of inhibition suggesting that anti-microbial doped nanoclay enriched hydrogels can prevent the growth of bacteria. The release of gentamicin sulfate for a period of five days from the nanoclay-enriched hydrogels would supply anti-microbial agents in a sustained and controlled manner and assist in preventing microbial growth and biofilm formation on the titanium implant surface. A pilot study, using mouse osteoblasts, confirmed that the nanoclay enriched surfaces are also cell supportive as osteoblasts readily, proliferated and produced a type I collagen and proteoglycan matrix.

  1. A Summary of Actinide Enrichment Technologies and Capability Gaps

    Energy Technology Data Exchange (ETDEWEB)

    Patton, Bradley D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Robinson, Sharon M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-01-01

    The evaluation performed in this study indicates that a new program is needed to efficiently provide a national actinide radioisotope enrichment capability to produce milligram-to-gram quantities of unique materials for user communities. This program should leverage past actinide enrichment, the recent advances in stable isotope enrichment, and assessments of the future requirements to cost effectively develop this capability while establishing an experience base for a new generation of researchers in this vital area. Preliminary evaluations indicate that an electromagnetic isotope separation (EMIS) device would have the capability to meet the future needs of the user community for enriched actinides. The EMIS technology could be potentially coupled with other enrichment technologies, such as irradiation, as pre-enrichment and/or post-enrichment systems to increase the throughput, reduce losses of material, and/or reduce operational costs of the base EMIS system. Past actinide enrichment experience and advances in the EMIS technology applied in stable isotope separations should be leveraged with this new evaluation information to assist in the establishment of a domestic actinide radioisotope enrichment capability.

  2. Use of Olive Oil Industrial By-Product for Pasta Enrichment.

    Science.gov (United States)

    Padalino, Lucia; D'Antuono, Isabella; Durante, Miriana; Conte, Amalia; Cardinali, Angela; Linsalata, Vito; Mita, Giovanni; Logrieco, Antonio F; Del Nobile, Matteo Alessandro

    2018-04-16

    During recent years food industries generally produce a large volume of wastes both solid and liquid, representing a disposal and potential environmental pollution problem. The goal of the study was to optimize, from both sensory and nutritional points of view, the formulation of durum wheat spaghetti enriched with an olive oil industrial by-product, indicated as olive paste. Three consecutive steps were carried out. In the first one, the olive paste was air-dried at low temperature, milled to record olive paste flour and properly analyzed for its biochemical composition. In the second step, the olive paste flour was added to the pasta dough at 10% and 15% ( w / w ). In the last step, different concentrations of transglutaminase were added to enriched pasta (10% olive paste) to further improve the quality. Sensory properties and nutritional content of enriched and control pasta were properly measured. Spaghetti with 10% olive paste flour and 0.6% transglutaminase were considered acceptable to the sensory panel test. Nutritional analyses showed that addition of 10% olive paste flour to pasta considerably increased content of flavonoids and total polyphenols. The proper addition of olive paste flour and transglutaminase for pasta enrichment could represent a starting point to valorize olive oil industrial by-products and produce new healthy food products.

  3. Uranium enrichment (a strategy analysis overview)

    International Nuclear Information System (INIS)

    Blahnik, C.

    1979-08-01

    An analysis of available information on enrichment technology, separative work supply and demand, and SWU cost is presented. Estimates of present and future enrichment costs are provided for use in strategy analyses of alternate nuclear fuel cycles and systems. (auth)

  4. Providing incentives to buy US enrichment

    International Nuclear Information System (INIS)

    Steyn, J.

    1985-01-01

    The U.S. Department of Energy is making a series of commercial and technological decisions crucial to its future as an enriching enterprise. The state of US enrichment, as revealed in this years AIF Fuel Cycle conference, is reported. (U.K.)

  5. Enhanced production and isotope enrichment of recombinant glycoproteins produced in cultured mammalian cells

    Energy Technology Data Exchange (ETDEWEB)

    Skelton, David; Goodyear, Abbey [Florida State University, Department of Chemistry and Biochemistry (United States); Ni, DaQun; Walton, Wendy J.; Rolle, Myron; Hare, Joan T. [Florida State University, Institute of Molecular Biophysics (United States); Logan, Timothy M., E-mail: tlogan@fsu.ed [Florida State University, Department of Chemistry and Biochemistry (United States)

    2010-10-15

    NMR studies of post-translationally modified proteins are complicated by the lack of an efficient method to produce isotope enriched recombinant proteins in cultured mammalian cells. We show that reducing the glucose concentration and substituting glutamate for glutamine in serum-free medium increased cell viability while simultaneously increasing recombinant protein yield and the enrichment of non-essential amino acids compared to culture in unmodified, serum-free medium. Adding dichloroacetate, a pyruvate dehydrogenase kinase inhibitor, further improves cell viability, recombinant protein yield, and isotope enrichment. We demonstrate the method by producing partially enriched recombinant Thy1 glycoprotein from Lec1 Chinese hamster ovary (CHO) cells using U-{sup 13}C-glucose and {sup 15}N-glutamate as labeled precursors. This study suggests that uniformly {sup 15}N,{sup 13}C-labeled recombinant proteins may be produced in cultured mammalian cells starting from a mixture of labeled essential amino acids, glucose, and glutamate.

  6. Enhanced production and isotope enrichment of recombinant glycoproteins produced in cultured mammalian cells

    International Nuclear Information System (INIS)

    Skelton, David; Goodyear, Abbey; Ni, DaQun; Walton, Wendy J.; Rolle, Myron; Hare, Joan T.; Logan, Timothy M.

    2010-01-01

    NMR studies of post-translationally modified proteins are complicated by the lack of an efficient method to produce isotope enriched recombinant proteins in cultured mammalian cells. We show that reducing the glucose concentration and substituting glutamate for glutamine in serum-free medium increased cell viability while simultaneously increasing recombinant protein yield and the enrichment of non-essential amino acids compared to culture in unmodified, serum-free medium. Adding dichloroacetate, a pyruvate dehydrogenase kinase inhibitor, further improves cell viability, recombinant protein yield, and isotope enrichment. We demonstrate the method by producing partially enriched recombinant Thy1 glycoprotein from Lec1 Chinese hamster ovary (CHO) cells using U- 13 C-glucose and 15 N-glutamate as labeled precursors. This study suggests that uniformly 15 N, 13 C-labeled recombinant proteins may be produced in cultured mammalian cells starting from a mixture of labeled essential amino acids, glucose, and glutamate.

  7. Synthesis of 15N-enriched fertilizers. Pt. II. Synthesis of 15N-enriched urea

    International Nuclear Information System (INIS)

    Bondassolli, J.A.; Trivelin, P.C.O.; Mortatti, J.; Victoria, R.L.

    1988-01-01

    The results of studies on the production of 15 N-urea through the reaction between 15 N-enriched anhidrous ammonia, carbon monoxide and sulfur, using hydrogen sulfite as a auto catalizers and methyl alcohol as a liquid reaction medium is presented. The influence of the quantities of reagents on final yield of synthesised urea were studied. Analysis of the cost of 5 Atoms % 15 N-enriched urea were made. (M.A.C.) [pt

  8. Concept and nuclear performance of direct-enrichment fusion breeder blanket using UO2 powder

    International Nuclear Information System (INIS)

    Oka, Yoshiaki; Kasahara, Takayasu; An, Shigehiro

    1985-01-01

    A new concept is presented for direct enrichment of fissile fuel in the blanket of a fusion-fission hybrid reactor. The enriched fuel produced by this means can be used in fission reactors without reprocessing. The outstanding feature of the concept is the powdered form in which UO 2 fuel is placed in the reactor blanket, where it is irradiated to the requisite enrichment for use as fuel in burner reactor, e.g. 3%. After removal from blanket, the powder is mixed to homogenize the enrichment. Fuel pellets and assemblies are then fabricated from the powder without reprocessing. The concept of irradiating UO 2 in powder eliminates the problems of spatial nonuniformity in fissile enrichment, and of radiation damage to fuel clad, encountered in attempting to enrich prefabricated fuel. Powder mixing for homogenization brings the additional benefit of removing volatile fission products. Also burnable poison can be added, as necessary, after irradiation. An extensive neutronic parameter survey showed that the optimum blanket arrangement for this enrichment concept is one presenting a fission suppressing configuration and with beryllium adopted as moderator. By this arrangement, the average 239 Pu enrichment obtained on the natural UO 2 fuel in the blanket reaches 3% after only 0.56 MW.yr/m"2 exposure. A conceptual design is presented of the blanket, together with associated fusion breeder, from which, practical application of the concept is shown to be promising. (author)

  9. Boron isotopic enrichment by displacement chromatography

    International Nuclear Information System (INIS)

    Mohapatra, K.K.; Bose, Arun

    2014-01-01

    10 B enriched boron is used in applications requiring high volumetric neutron absorption (absorption cross section- 3837 barn for thermal and 1 barn for 1 MeV fast neutron). It is used in fast breeder reactor (as control rod material), in neutron counter, in Boron Neutron Capture Therapy etc. Owing to very small separation factor, boron isotopic enrichment is a complex process requiring large number of separation stages. Heavy Water Board has ventured in industrial scale production of 10 B enriched boron using Exchange Distillation Process as well as Ion Displacement Chromatography Process. Ion Displacement Chromatography process is used in Boron Enrichment Plant at HWP, Manuguru. It is based on isotopic exchange between borate ions (B(OH) 4 - ) on anion exchange resin and boric acid passing through resin. The isotopic exchange takes place due to difference in zero point energy of 10 B and 11 B

  10. High Efficient Enrichment and Activated Dissolution of Refractory Low Grade Rh-containing Material

    Institute of Scientific and Technical Information of China (English)

    WU Xiaofeng; DONG Haigang; TONG Weifeng; ZHAO Jiachun; ZENG Rui

    2012-01-01

    Aiming to the low-grade rhodium-containing waste materials,a new process was proposed to enrich and activate rhodium by smelting using iron oxide as a trapping agent and activator.A rhodium concentrate was obtained by the separation of base metals and precious metals.The concentrate was reacted with dilute aqua regia to obtain rhodium solution.The factors influencing the enrichment and activation effects were discussed in this paper.The results showed that the dissolution rate is greater than 99% under the optimum conditions.In this process,the activation of rhodium was finished in the enrichment process.The iron oxide is both a trapping agent and activator,which simplifies the process and reduce the cost.

  11. Long term assurance of supply of uranium enrichment

    International Nuclear Information System (INIS)

    1978-01-01

    After elaborating a number of key questions on uranium enrichment, the representatives of 10 countries and of the EC commission present their answers. Attention is paid to the assurance of uranium supply, to uranium enrichment, market trends and flexibility in enrichment agreements

  12. GOMA: functional enrichment analysis tool based on GO modules

    Institute of Scientific and Technical Information of China (English)

    Qiang Huang; Ling-Yun Wu; Yong Wang; Xiang-Sun Zhang

    2013-01-01

    Analyzing the function of gene sets is a critical step in interpreting the results of high-throughput experiments in systems biology.A variety of enrichment analysis tools have been developed in recent years,but most output a long list of significantly enriched terms that are often redundant,making it difficult to extract the most meaningful functions.In this paper,we present GOMA,a novel enrichment analysis method based on the new concept of enriched functional Gene Ontology (GO) modules.With this method,we systematically revealed functional GO modules,i.e.,groups of functionally similar GO terms,via an optimization model and then ranked them by enrichment scores.Our new method simplifies enrichment analysis results by reducing redundancy,thereby preventing inconsistent enrichment results among functionally similar terms and providing more biologically meaningful results.

  13. A Balanced Approach to Building STEM College and Career Readiness in High School: Combining STEM Intervention and Enrichment Programs

    Science.gov (United States)

    Rakich, Sladjana S.; Tran, Vinh

    2016-01-01

    Often STEM schools and STEM enrichment programs attract primarily high achieving students or those with strong motivation or interest. However, to ensure that more students pursue interest in STEM, steps must be taken to provide access for all students. For a balanced and integrated career development focus, schools must provide learning…

  14. Virtual Environmental Enrichment through Video Games Improves Hippocampal-Associated Memory.

    Science.gov (United States)

    Clemenson, Gregory D; Stark, Craig E L

    2015-12-09

    The positive effects of environmental enrichment and their neural bases have been studied extensively in the rodent (van Praag et al., 2000). For example, simply modifying an animal's living environment to promote sensory stimulation can lead to (but is not limited to) enhancements in hippocampal cognition and neuroplasticity and can alleviate hippocampal cognitive deficits associated with neurodegenerative diseases and aging. We are interested in whether these manipulations that successfully enhance cognition (or mitigate cognitive decline) have similar influences on humans. Although there are many "enriching" aspects to daily life, we are constantly adapting to new experiences and situations within our own environment on a daily basis. Here, we hypothesize that the exploration of the vast and visually stimulating virtual environments within video games is a human correlate of environmental enrichment. We show that video gamers who specifically favor complex 3D video games performed better on a demanding recognition memory task that assesses participants' ability to discriminate highly similar lure items from repeated items. In addition, after 2 weeks of training on the 3D video game Super Mario 3D World, naive video gamers showed improved mnemonic discrimination ability and improvements on a virtual water maze task. Two control conditions (passive and training in a 2D game, Angry Birds), showed no such improvements. Furthermore, individual performance in both hippocampal-associated behaviors correlated with performance in Super Mario but not Angry Birds, suggesting that how individuals explored the virtual environment may influence hippocampal behavior. The hippocampus has long been associated with episodic memory and is commonly thought to rely on neuroplasticity to adapt to the ever-changing environment. In animals, it is well understood that exposing animals to a more stimulating environment, known as environmental enrichment, can stimulate neuroplasticity and

  15. Work-family enrichment, work-family conflict, and marital satisfaction: a dyadic analysis.

    Science.gov (United States)

    van Steenbergen, Elianne F; Kluwer, Esther S; Karney, Benjamin R

    2014-04-01

    This study was designed to examine whether spouses' work-to-family (WF) enrichment experiences account for their own and their partner's marital satisfaction, beyond the effects of WF conflict. Data were collected from both partners of 215 dual-earner couples with children. As hypothesized, structural equation modeling revealed that WF enrichment experiences accounted for variance in individuals' marital satisfaction, over and above WF conflict. In line with our predictions, this positive link between individuals' WF enrichment and their marital satisfaction was mediated by more positive marital behavior, and more positive perceptions of the partner's behavior. Furthermore, evidence for crossover was found. Husbands who experienced more WF enrichment were found to show more marital positivity (according to their wives), which related to increased marital satisfaction in their wives. No evidence of such a crossover effect from wives to husbands was found. The current findings not only highlight the added value of studying positive spillover and crossover effects of work into the marriage, but also suggest that positive spillover and crossover effects on marital satisfaction might be stronger than negative spillover and crossover are. These results imply that organizational initiatives of increasing job enrichment may make employees' marital life happier and can contribute to a happy, healthy, and high-performing workforce.

  16. Multiplex target enrichment using DNA indexing for ultra-high throughput SNP detection.

    LENUS (Irish Health Repository)

    Kenny, Elaine M

    2011-02-01

    Screening large numbers of target regions in multiple DNA samples for sequence variation is an important application of next-generation sequencing but an efficient method to enrich the samples in parallel has yet to be reported. We describe an advanced method that combines DNA samples using indexes or barcodes prior to target enrichment to facilitate this type of experiment. Sequencing libraries for multiple individual DNA samples, each incorporating a unique 6-bp index, are combined in equal quantities, enriched using a single in-solution target enrichment assay and sequenced in a single reaction. Sequence reads are parsed based on the index, allowing sequence analysis of individual samples. We show that the use of indexed samples does not impact on the efficiency of the enrichment reaction. For three- and nine-indexed HapMap DNA samples, the method was found to be highly accurate for SNP identification. Even with sequence coverage as low as 8x, 99% of sequence SNP calls were concordant with known genotypes. Within a single experiment, this method can sequence the exonic regions of hundreds of genes in tens of samples for sequence and structural variation using as little as 1 μg of input DNA per sample.

  17. Study of Fuel Rods Axial Enrichment Distribution Effect on the Neutronic Parameters of the Reactor Core

    International Nuclear Information System (INIS)

    Pazirandeh, A.; Nasiri, S. H.

    2012-01-01

    Optimization of the fuel burn up is an important issue in nuclear reactor fuel management and technology. Radial enrichment distribution in the reactor core is a conventional method and axial enrichment is constant along the fuel rod. In this article, the effects of axial enrichment distribution variation on neutronic parameters of PWR core are studied. The axial length of the core is divided into ten sections, considering axial enrichment variation and leaving the existing radial enrichment distribution intact. This study shows that the radial and axial power peaking factors are decreased as compared with the typical conventional core. In addition, the first core lifetime lasts 30 days longer than normal PWR core. Moreover, at the same time boric acid density is 0.2 g/kg at the beginning of the cycle. The flux shape is also flat at the beginning of the cycle for the proposed configuration of the axially enrichment distribution.

  18. Enrichment of light hydrocarbon mixture

    Science.gov (United States)

    Yang,; Dali, [Los Alamos, NM; Devlin, David [Santa Fe, NM; Barbero, Robert S [Santa Cruz, NM; Carrera, Martin E [Naperville, IL; Colling, Craig W [Warrenville, IL

    2010-08-10

    Light hydrocarbon enrichment is accomplished using a vertically oriented distillation column having a plurality of vertically oriented, nonselective micro/mesoporous hollow fibers. Vapor having, for example, both propylene and propane is sent upward through the distillation column in between the hollow fibers. Vapor exits neat the top of the column and is condensed to form a liquid phase that is directed back downward through the lumen of the hollow fibers. As vapor continues to ascend and liquid continues to countercurrently descend, the liquid at the bottom of the column becomes enriched in a higher boiling point, light hydrocarbon (propane, for example) and the vapor at the top becomes enriched in a lower boiling point light hydrocarbon (propylene, for example). The hollow fiber becomes wetted with liquid during the process.

  19. Uranium enrichment capacity: public versus private ownership

    International Nuclear Information System (INIS)

    Fraser, J.T.

    1977-01-01

    Continual growth of conventional nuclear capacity requires an assured supply of enriched uranium and, hence, potential expansion of domestic uranium enrichment capacity. The question of ownership of new enrichment capacity, i.e., public or private, entails not only the social-opportunity costs of alternative investments but also technical parameters of uranium utilization and advanced reactor development. Inclusion of risk preferences in both the public and private sectors produces interesting results in terms of optimal investment strategies with respect to choice of technology and scale of investment. Utilization of a nuclear fuel cycle requirements process model allows explicit specification of production technology. Integration of process model output with a least-cost investment model permits flexibility in parametric analysis. Results indicate minimum incentive for Government subsidy of a private enrichment sector through 2000 given moderate to low nuclear growth assumptions. The long-run scenario, to 2020, exhibits potentially greater incentives for private enrichment investment

  20. Evaluation of the uranium enrichment demonstration plant project

    International Nuclear Information System (INIS)

    Sugitsue, Noritake

    2001-01-01

    In this report, the organization system of the uranium enrichment business is evaluated, based on the operation of the uranium enrichment demonstration plant. As a result, in uranium enrichment technology development or business, it was acknowledged that maintenance of the organization which has the Trinity of a research/engineering/operation was necessary in an industrialization stage by exceptional R and D cycle. Japan Nuclear Fuel Ltd. (JNFL) set up the Rokkashomura Aomori Uranium Enrichment Research and Development Center in November 2000. As a result, the system that company directly engaged in engineering development was prepared. And results obtained in this place is expected toward certain establishment of the uranium enrichment business of Japan. (author)

  1. Uranium enrichment: a vital new industry

    International Nuclear Information System (INIS)

    1975-10-01

    The energy problem facing the nation and the need for nuclear power are pointed out. Uranium enrichment and the demand for it are discussed. Reasons for, and obstacles to, private enrichment are outlined. The President's plan (including the Nuclear Fuel Assurance Act) is summarized

  2. The Helikon technique for isotope enrichment

    International Nuclear Information System (INIS)

    Haarhoff, P.C.

    1976-11-01

    The separating element employed in the UCOR process for uranium enrichment has an enriched stream which is much smaller than the depleted stream. To deal with this small cut and to exploit the full potential of the process, a new cascade technique has been developed, the so-called helikon technique. It is based on the principle that an axial flow compressor can simultaneously compress a number of streams of different isotopic composition, which flow through it in parallel, without any significant mixing between them. The technique makes it possible to achieve the desired enrichment with a relatively small number of separating units, by making the best use of the high enrichment factor available. A further feature of the helikon technique is that a module yields an enrichment factor which is not constant, but can vary. In this way a cascade can be built up from modules of a fixed size, which is a great advantage when compared to conventional cascade arrangements where several unit sizes are required. A general theoretical treatment of the helikon technique is given and the similarity between helikon and conventional cascades is pointed out. Practical helikon cascades are subsequently discussed on the basis of the UCOR process

  3. Final Activity Report: The Effects of Iron Complexing Ligands on the Long Term Ecosystem Response to Iron Enrichment of HNLC waters

    Energy Technology Data Exchange (ETDEWEB)

    Trick, Charles Gordon [Western University

    2013-07-30

    Substantial increases in the concentrations of the stronger of two Fe(III) complexing organic ligand classes measured during the mesoscale Fe enrichment studies IronEx II and SOIREE appeared to sharply curtailed Fe availability to diatoms and thus limited the efficiency of carbon sequestration to the deep. Detailed observations during IronEx II (equatorial Pacific Ocean) and SOIREE (Southern Ocean –Pacific sector) indicate that the diatoms began re-experiencing Fe stress even though dissolved Fe concentrations remained elevated in the patch. This surprising outcome likely is related to the observed increased concentrations of strong Fe(III)-complexing ligands in seawater. Preliminary findings from other studies indicate that diatoms may not readily obtain Fe from these chemical species whereas Fe bound by strong ligands appears to support growth of cyanobacteria and nanoflagellates. The difficulty in assessing the likelihood of these changes with in-situ mesoscale experiments is the extended monitoring period needed to capture the long-term trajectory of the carbon cycle. A more detailed understanding of Fe complexing ligand effects on long-term ecosystem structure and carbon cycling is essential to ascertain not only the effect of Fe enrichment on short-term carbon sequestration in the oceans, but also the potential effect of Fe enrichment in modifying ecosystem structure and trajectory.

  4. 31 CFR 540.306 - Highly Enriched Uranium (HEU).

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Highly Enriched Uranium (HEU). 540...) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY HIGHLY ENRICHED URANIUM (HEU) AGREEMENT ASSETS CONTROL REGULATIONS General Definitions § 540.306 Highly Enriched Uranium (HEU). The term highly...

  5. Strong Selection Significantly Increases Epistatic Interactions in the Long-Term Evolution of a Protein.

    Directory of Open Access Journals (Sweden)

    Aditi Gupta

    2016-03-01

    Full Text Available Epistatic interactions between residues determine a protein's adaptability and shape its evolutionary trajectory. When a protein experiences a changed environment, it is under strong selection to find a peak in the new fitness landscape. It has been shown that strong selection increases epistatic interactions as well as the ruggedness of the fitness landscape, but little is known about how the epistatic interactions change under selection in the long-term evolution of a protein. Here we analyze the evolution of epistasis in the protease of the human immunodeficiency virus type 1 (HIV-1 using protease sequences collected for almost a decade from both treated and untreated patients, to understand how epistasis changes and how those changes impact the long-term evolvability of a protein. We use an information-theoretic proxy for epistasis that quantifies the co-variation between sites, and show that positive information is a necessary (but not sufficient condition that detects epistasis in most cases. We analyze the "fossils" of the evolutionary trajectories of the protein contained in the sequence data, and show that epistasis continues to enrich under strong selection, but not for proteins whose environment is unchanged. The increase in epistasis compensates for the information loss due to sequence variability brought about by treatment, and facilitates adaptation in the increasingly rugged fitness landscape of treatment. While epistasis is thought to enhance evolvability via valley-crossing early-on in adaptation, it can hinder adaptation later when the landscape has turned rugged. However, we find no evidence that the HIV-1 protease has reached its potential for evolution after 9 years of adapting to a drug environment that itself is constantly changing. We suggest that the mechanism of encoding new information into pairwise interactions is central to protein evolution not just in HIV-1 protease, but for any protein adapting to a changing

  6. Enrichment behavior and transport mechanism of soil-bound PAHs during rainfall-runoff events.

    Science.gov (United States)

    Zheng, Yi; Luo, Xiaolin; Zhang, Wei; Wu, Bin; Han, Feng; Lin, Zhongrong; Wang, Xuejun

    2012-12-01

    Polycyclic Aromatic Hydrocarbons (PAHs) transported by surface runoff result in nonpoint source pollution and jeopardize aquatic ecosystems. The transport mechanism of PAHs during rainfall-runoff events has been rarely studied regarding pervious areas. An experimental system was setup to simulate the runoff pollution process on PAHs-contaminated soil. The enrichment behavior of soil-bound PAHs was investigated. The results show that soil organic matters (SOM), rather than clay particles, seem to be the main carrier of PAHs. The enrichment is highly conditioned on runoff and erosion processes, and its magnitude varies among PAH compounds. It is not feasible to build a simple and universal relationship between enrichment ratio and sediment discharge following the traditional enrichment theory. To estimate the flux of PAHs from pervious areas, soil erosion process has to be clearly understood, and both organic carbon content and composition of SOM should be factored into the calculation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. An isotopic analysis system for plutonium samples enriched in 238Pu

    International Nuclear Information System (INIS)

    Ruhter, W.D.; Camp, D.C.

    1991-08-01

    We have designed and built a gamma-ray spectrometer system that measures the relative plutonium isotopic abundances of plutonium oxide enriched in 238 Pu. The first system installed at Westinghouse Savannah River Company was tested and evaluated on plutonium oxide in stainless steel EP60/61 containers. 238 Pu enrichments ranged from 20% to 85%. Results show that 200 grams of plutonium oxide in an EP60.61 container can be measured with ±0.3% precision and better than ±1.0% accuracy in the specific power using a counting time of 50 minutes. 3 refs., 2 figs

  8. Community-aware user profile enrichment in folksonomy.

    Science.gov (United States)

    Xie, Haoran; Li, Qing; Mao, Xudong; Li, Xiaodong; Cai, Yi; Rao, Yanghui

    2014-10-01

    In the era of big data, collaborative tagging (a.k.a. folksonomy) systems have proliferated as a consequence of the growth of Web 2.0 communities. Constructing user profiles from folksonomy systems is useful for many applications such as personalized search and recommender systems. The identification of latent user communities is one way to better understand and meet user needs. The behavior of users is highly influenced by the behavior of their neighbors or community members, and this can be utilized in constructing user profiles. However, conventional user profiling techniques often encounter data sparsity problems as data from a single user is insufficient to build a powerful profile. Hence, in this paper we propose a method of enriching user profiles based on latent user communities in folksonomy data. Specifically, the proposed approach contains four sub-processes: (i) tag-based user profiles are extracted from a folksonomy tripartite graph; (ii) a multi-faceted folksonomy graph is constructed by integrating tag and image affinity subgraphs with the folksonomy tripartite graph; (iii) random walk distance is used to unify various relationships and measure user similarities; (iv) a novel prototype-based clustering method based on user similarities is used to identify user communities, which are further used to enrich the extracted user profiles. To evaluate the proposed method, we conducted experiments using a public dataset, the results of which show that our approach outperforms previous ones in user profile enrichment. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. PURIFICATION AND ENRICHMENT OF BIOGAS IN ASH-WATER MIXTURE

    Directory of Open Access Journals (Sweden)

    Andrzej Brudniak

    2014-10-01

    Full Text Available Biogas, produced in an aerobic digestion process, is a mixture of gases, and that is why its inexpensive and effective valorisation is essential. Research on this process is necessary in order to use biogas as a renewable energy source. The aim of this thesis is to present methods of biogas purification and enrichment in the fly ash - water mixture, that is generated on the base of fly ash produced during burning coal in power industry. Experience presented that the fly ash absorbs CO2 and H2S, even in conventional conditions. The absorption efficiency depends not only on the chemical composition of the ash but also on its physical properties. There was also a strong neutralization of alkaline waste combustion.

  10. Accumulation of enriched uranium UO2F2 in ultrastructure as studied by electron microscopic autoradiography

    International Nuclear Information System (INIS)

    Zhu Shoupeng; Wang Yuanchang

    1992-01-01

    A study was made on the retention of soluble enriched uranium UO 2 F 2 in ultrastructure by electron microscopic autoradiography. The early dynamic accumulation of radioactivity in the body showed that enriched uranium UO 2 F 2 was mainly localized in kidneys, especially accumulated in epithelial cells of proximal convoluted tubules leading to degeneration and necrosis of the tubules. In liver cells, enriched uranium UO 2 F 2 at first deposited in nuclei of the cells and in soluble proteins of the plasma, and later accumulated selectively in mitochondria and lysosomes. On electron microscopic autoradiographic study it was shown that the dynamic retention of radioactivity of enriched uranium UO 2 F 2 in skeleton increased steadily through the time period of exposure. Enriched uranium UO 2 F 2 chiefly deposited in nuclei and mitochondria of osteoblasts as well as of osteoclasts

  11. Proton hopping mechanism in solid polymer electrolysis demonstrated by tritium enrichment and electro-osmotic drag measurement

    International Nuclear Information System (INIS)

    Saito, Masaaki; Imaizumi, Hiroshi; Kato, Norio; Ishii, Yoshiyuki; Saito, Keiichi

    2010-01-01

    Anomalies in tritium enrichment cannot be explained only by isotopic effects in water electrolysis. The temperature dependence of the enrichment factor had been reported as increasing with 1/T. However, the increase was difficult to explain on the basis of kinetics. In this study, electro-osmotic drag (EOD, number of water molecule accompanied by a proton) and tritium enrichment ratio were investigated using light water (H 2 O) and heavy water (D 2 O) by solid polymer electrolysis. The EOD decreased and tritium enrichment ratio increased at low temperature for H 2 O. Electrolysis showed no temperature dependence for D 2 O. It was revealed that proton hopping by a hydrogen bond network of water molecules (the Grotthuss mechanism) affects the temperature dependence of EOD and tritium enrichment in the case of H 2 O. (author)

  12. Strong Bisimilarity of Simple Process Algebras

    DEFF Research Database (Denmark)

    Srba, Jirí

    2003-01-01

    We study bisimilarity and regularity problems of simple process algebras. In particular, we show PSPACE-hardness of the following problems: (i) strong bisimilarity of Basic Parallel Processes (BPP), (ii) strong bisimilarity of Basic Process Algebra (BPA), (iii) strong regularity of BPP, and (iv......) strong regularity of BPA. We also demonstrate NL-hardness of strong regularity problems for the normed subclasses of BPP and BPA. Bisimilarity problems of simple process algebras are introduced in a general framework of process rewrite systems, and a uniform description of the new techniques used...

  13. Facile synthesis of thiol-polyethylene glycol functionalized magnetic titania nanomaterials for highly efficient enrichment of N-linked glycopeptides.

    Science.gov (United States)

    Wang, Jiawen; Yao, Jizong; Sun, Nianrong; Deng, Chunhui

    2017-08-25

    As protein N-glycosylation involved in generation and development of various cancers and diseases, it is vital to capture glycopeptides from complex biological samples for biomarker discovery. In this work, by taking advantages of the interaction between titania and thiol groups, thiol-polyethylene glycol functionalized magnetic titania nanomaterials (denoted as Fe 3 O 4 @TiO 2 @PEG) were firstly fabricated as an excellent hydrophilic adsorbent of N-linked glycopeptides. On one hand, the special interaction of titanium-thiol makes the synthetic manipulation simple and provides a new idea for design and synthesis of novel nanomaterials; on the other hand, strong magnetic response could realize rapid separation and the outstanding hydrophilicity of polyethylene glycol makes Fe 3 O 4 @TiO 2 @PEG nanomaterials show superior performance for glycopeptides enrichment with ultralow limit of detection (0.1mol/μL) and high selectivity (1:100). As a result, 24 and 33 glycopeptides enriched from HRP and IgG digests were identified respectively by MALDI-TOF MS, and 300 glycopeptides corresponding to 106 glycoproteins were recognized from merely 2μL human serum, indicating a great potential of Fe 3 O 4 @TiO 2 @PEG nanomaterials for glycoproteomic research. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Enriched uranium recovery flowsheet improvements

    International Nuclear Information System (INIS)

    Holt, D.L.

    1986-01-01

    Savannah River uses 7.5% TBP to recover and purify enriched uranium. Adequate decontamination from fission products is necessary to reduce personnel exposure and to ensure that the enriched uranium product meets specifications. Initial decontamination of the enriched uranium from the fission products is carried out in the 1A bank, 16 stages of mixer-settlers. Separation of the enriched uranium from the fission product, 95 Zr, has been adequate, but excessive solvent degradation caused by the long phase contact times in the mixer-settlers has limited the 95 Zr decontamination factor (DF). An experimental program is investigating the replacement of the current 1A bank with either centrifugal contactors or a combination of centrifugal contactors and mixer-settlers. Experimental work completed has compared laboratory-scale centrifugal contactors and mixer-settlers for 95 Zr removal efficiencies. Feed solutions spiked with actual plant solutions were used. The 95 Zr DF was significantly better in the mixer-settlers than in the centrifugal contactors. As a result of this experimental study, a hybrid equipment flowsheet has been proposed for plant use. The hybrid equipment flowsheet combines the advantages of both types of solvent extraction equipment. Centrifugal contactors would be utilized in the extraction and initial scrub sections, followed by additional scrub stages of mixer-settlers

  15. Stable isotope enrichment by thermal diffusion

    International Nuclear Information System (INIS)

    Vasaru, Gheorghe

    2003-01-01

    Thermal diffusion (TD) in both gaseous and liquid phase has been the subject of extensive experimental and theoretical investigations, especially after the invention by K. Clusius and G. Dickel of the thermal diffusion column, sixty years ago. This paper gives a brief overview of the most important applications and developments of this transport phenomenon for enrichment of 13 C and of some noble gases isotopes in our institute. The results of calculations of the transport coefficients H and K for a concentric tube type TD column, operated with methane as process gas, are presented. Static separation factor at equilibrium vs gas pressure has been calculated for various molecular models. The experimental separation factors for different gas pressure were found to be consistent with those calculated for the inverse power repulsion model and the Lennard-Jones model. The most important characteristics of a seven-stage cascade consisting of 19 TD columns of concentric tube type are given. This system has been constructed and successfully operated at a temperature of 673 K and produces an enrichment of methane of natural isotopic 13 C abundance, up to the concentration of 25% 13 CH 4 . Enrichment of the noble gases isotopes implies: - a . Enrichment of 20 Ne and 22 Ne in a eight-stage cascade consisting of 8 TD columns; - b. enrichment of 46 Ar in a seven-stage cascade consisting of TD columns and finally; - c. enrichment of 78 Kr and 86 Kr in a fifteen-stage cascade, consisting of 35 TD columns. For all these installations we have adopted TD columns of hot wire type (4 m in length), operated at a temperature of 1073 K. (author)

  16. Optimization of enrichment zones that maximize the regeneration profits in a fast reactor

    International Nuclear Information System (INIS)

    Jachic, J.

    1983-01-01

    Using a simplified model of Super Phenix reactor, the admissible limits of internal and external enrichment core without control rods, that assure an auto-stability related to fuel Doppler coefficient were determined. A Linear Programming System was developed to solve this problem, using the SIMPLEX method. The solution showed that the regeneration profits could be increased at least in 14% if the internal enrichment core decrease 0.97 and the external 0.3%. (E.G.) [pt

  17. Arsenic enrichment and mobilization in the Holocene alluvial aquifers of the Chapai-Nawabganj district, Bangladesh: A geochemical and statistical study

    International Nuclear Information System (INIS)

    Reza, A.H.M. Selim; Jean, Jiin-Shuh; Lee, Ming-Kuo; Yang, Huai-Jen; Liu, Chia-Chuan

    2010-01-01

    Research highlights: → Four factors (i.e., salinity factor, As-enrichment factor, reduction factor, and hardness factor) control groundwater geochemistry. → Hydrochemical facies analysis showed that most of the water samples are dominated by Ca and HCO 3 ions. → Cluster 1 water types are highly enriched in As; an alternative water source is thus needed for domestic water supply. Possible solutions are to install tube wells in the deeper Pleistocene aquifers or use clean surface water sources such as reservoirs or rain water. → Cluster 4 water types contain low concentration As, below the Bangladesh standard ( 4 , total dissolved solids (TDS), and electrical conductivity (EC) are grouped under the first factor representing the salinity sources of waters. The second factor, represented by As and Mn, is related to As mobilization processes. The third factor of Fe and alkalinity is strongly influenced by bacterial Fe(III) reduction which would raise both Fe and HCO 3 - concentrations in water. The fourth factor of Ca and Mg reflects the hardness of the Ca-HCO 3 type of groundwater, which is confirmed by the hydrochemical facies analysis. Cluster analysis leads to the formulation of four water types including highly, moderately, and slightly As-enriched groundwater as well as groundwater with elevated SO 4 2- , from anthropogenic sources. Multivariate analyses of the geochemical parameters suggest that Fe- and Mn-oxyhydroxides and mineral phases of phyllosilicates (e.g., biotite) are the main hosts of As in the sediments. Statistical analysis also shows that As is closely associated with Fe and Mn in sediments while As is positively correlated with Mn in groundwater. These correlations along with results of sequential leaching experiments suggest that reductive dissolution of MnOOH and FeOOH mediated by anaerobic bacteria represents an important mechanism for releasing As into the groundwater.

  18. MICROBIOLOGICAL AND NUTRITIONAL QUALITY OF WARANKASHI ENRICHED BREAD

    Directory of Open Access Journals (Sweden)

    O. E. Dudu

    2012-08-01

    Full Text Available The study was carried out to determine the microbiological and nutritional quality, organoleptic, rheological and textural effect as well as the effect on the shelf life of wheat bread enriched with West African cottage cheese (warankashi at different substitution levels (1 %, 3 % and 5 %. The protein and fat content of wheat bread significantly increased but carbohydrate levels decreased significantly as enrichment with Warankashi increased. The amino acid profile of the wheat bread increased with increasing enrichment. The incorporation of Warankashi into wheat flour affected the rheological and textural properties of wheat flour; the rate of water absorption of the wheat flour decreased as Warankashi incorporation levels increased. Also, the dough stability time of the enriched flours was lesser than that of the wheat flour. The 3 % enrichment level had the highest dough consistency (520 BU. The extensibility of 1 % and 3 % wara bread dough were the same while that of wheat flour bread and 5 % Warankashi were the same. The 3 % wara bread dough had the highest resistance to extension. Shelf life of the bread remained unaffected by Warankashi incorporation but the rate of bacteria and fungi (yeast and mould growth decreased significantly (P < 0.05 as enrichment levels increased. There was no significant difference between the organoleptic properties of wheat bread to that of the enriched breads but the 3 % Warankshi enriched bread had the highest consumer acceptability.

  19. Safety aspects of gas centrifuge enrichment plants

    International Nuclear Information System (INIS)

    Hansen, A.H.

    1987-01-01

    Uranium enrichment by gas centrifuge is a commercially proven, viable technology. Gas centrifuge enrichment plant operations pose hazards that are also found in other industries as well as unique hazards as a result of processing and handling uranium hexafluoride and the handling of enriched uranium. Hazards also found in other industries included those posed by the use of high-speed rotating equipment and equipment handling by use of heavy-duty cranes. Hazards from high-speed rotating equipment are associated with the operation of the gas centrifuges themselves and with the operation of the uranium hexafluoride compressors in the tail withdrawal system. These and related hazards are discussed. It is included that commercial gas centrifuge enrichment plants have been designed to operate safely

  20. Uranium enrichment: an evolving market

    International Nuclear Information System (INIS)

    Longenecker, J.; Witzel, R.

    1997-01-01

    With over half of the world uranium enrichment market uncommitted to any supplier early in the next century, competition is certain to be fierce. In the meantime the outlood remains unclear, with the market dominated by a number of developments -privatisation of the United States Enrichment Corp (USEC), increasing availability of Russian and US military inventories, the deployment of advanced technology and the closure of nuclear power plants due to deregulation. (author)

  1. Experimental evidence of nitrogen control on pCO2 in phosphorus-enriched humic and clear coastal lagoon waters

    Science.gov (United States)

    Peixoto, Roberta B.; Marotta, Humberto; Enrich-Prast, Alex

    2013-01-01

    Natural and human-induced controls on carbon dioxide (CO2) in tropical waters may be very dynamic (over time and among or within ecosystems) considering the potential role of warmer temperatures intensifying metabolic responses and playing a direct role on the balance between photosynthesis and respiration. The high magnitude of biological processes at low latitudes following eutrophication by nitrogen (N) and phosphorus (P) inputs into coastal lagoons waters may be a relevant component of the carbon cycle, showing controls on partial pressure of CO2 (pCO2) that are still poorly understood. Here we assessed the strength of N control on pCO2 in P-enriched humic and clear coastal lagoons waters, using four experimental treatments in microcosms: control (no additional nutrients) and three levels of N additions coupled to P enrichments. In humic coastal lagoons waters, a persistent CO2 supersaturation was reported in controls and all nutrient-enriched treatments, ranging from 24- to 4-fold the atmospheric equilibrium value. However, both humic and clear coastal lagoons waters only showed significant decreases in pCO2 in relation to the controlled microcosms in the two treatments with higher N addition levels. Additionally, clear coastal lagoons water microcosms showed a shift from CO2 sources to CO2 sinks, in relation to the atmosphere. Only in the two more N-enriched treatments did pCO2 substantially decrease, from 650 µatm in controls and less N-enriched treatments to 10 µatm in more N-enriched microcosms. Humic substrates and N inputs can modulate pCO2 even in P-enriched coastal lagoons waters, thereby being important drivers on CO2 outgassing from inland waters. PMID:23390422

  2. Experimental evidence of nitrogen control on pCO2 in phosphorus-enriched humic and clear coastal lagoon waters

    Directory of Open Access Journals (Sweden)

    Roberta Bittencourt Peixoto

    2013-02-01

    Full Text Available Natural and human-induced controls on carbon dioxide (CO2 in tropical waters may be very dynamic (over time and among or within ecosystems considering the potential role of warmer temperatures intensifying metabolic responses and playing a direct role on the balance between photosynthesis and respiration. The high magnitude of biological processes at low latitudes following eutrophication by nitrogen (N and phosphorus (P inputs into inland waters may be a relevant component of the C cycle, showing controls on partial pressure of CO2 (pCO2 that are still poorly understood. Here we assessed the strength of N control on pCO2 in P-enriched humic and clear coastal lagoons waters, using four experimental treatments in microcosms: control (no additional nutrients and three levels of N additions coupled to P enrichments. In humic coastal lagoon waters, a persistent CO2 supersaturation was reported in controls and all nutrient-enriched treatments, ranging from 24-fold to fourfold the atmospheric equilibrium value. However, both humic and clear coastal lagoon waters only showed significant decreases in pCO2 in relation to the controlled microcosms in the two treatments with higher N addition levels. Additionally, clear coastal lagoon water microcosms showed a shift from CO2 sources to CO2 sinks, in relation to the atmosphere. Only in the two more N-enriched treatments did pCO2 substantially decrease, from 650 µatm in controls and less N-enriched treatments to 10 µatm in more N-enriched microcosms. Humic substrates and N inputs can modulate pCO2 even in P-enriched coastal lagoon waters, thereby being important drivers on CO2 outgassing from inland waters.

  3. Physicochemical and sensorial characteristics of noodle enriched with oyster mushroom (Pleorotus ostreatus) powder

    Science.gov (United States)

    Wahyono, A.; Novianti; Bakri, A.; Kasutjianingati

    2018-01-01

    Oyster Mushroom is a mushroom that can be used for food and medicine. It contains highly nutritious and functional substances such as statins and beta-glucan. A comprehensive evaluation of noodle-enriched with Oyster Mushroom powder has not been performed so far. In this study, we performed a comprehensive evaluation of noodle-enriched with Oyster Mushroom powder. The aim of this study was to assess the effects of enrichment of Oyster Mushroom Powder (OMP) on the quality of noodle. The quality of noodle was evaluated based on physical, chemical and sensorial characteristics. This study was done by substituting wheat flour with OMP at the level of 0 (control); 5; 7.5; 10; 12.5; and 15%. The results showed that OMP significantly affected (Pvalues of noodle.

  4. A theory of surface enrichment in ordered alloys

    NARCIS (Netherlands)

    Santen, van R.A.; Sachtler, W.M.H.

    1974-01-01

    A simple theory was developed to explain exptl. data on surface enrichment in Pt3Sn. The computed surface enrichment is in accord with exptl. findings. The theory predicts that in the Pt3Sn system enrichment occurs by interchange of atoms of the element with the lower heat of sublimation from the

  5. Detection of uranium enrichment activities using environmental monitoring techniques

    International Nuclear Information System (INIS)

    Belew, W.L.; Carter, J.A.; Smith, D.H.; Walker, R.L.

    1993-01-01

    Uranium enrichment processes have the capability of producing weapons-grade material in the form of highly enriched uranium. Thus, detection of undeclared uranium enrichment activities is an international safeguards concern. The uranium separation technologies currently in use employ UF 6 gas as a separation medium, and trace quantities of enriched uranium are inevitably released to the environment from these facilities. The isotopic content of uranium in the vegetation, soil, and water near the plant site will be altered by these releases and can provide a signature for detecting the presence of enriched uranium activities. This paper discusses environmental sampling and analytical procedures that have been used for the detection of uranium enrichment facilities and possible safeguards applications of these techniques

  6. Environmental Enrichment during Gestation Improves Behavior Consequences and Synaptic Plasticity in Hippocampus of Prenatal-Stressed Offspring Rats

    International Nuclear Information System (INIS)

    Li, Mingbo; Wang, Miao; Ding, Siqing; Li, Changqi; Luo, Xuegang

    2012-01-01

    Prenatal stress can result in various behavior deficits in offspring. Here we tested the effects of environmental enrichment during gestation used as a preventive strategy on the behavior deficits of prenatal-stressed offspring rats as well as the underlying structure basis. We compared the effect size of environmental enrichment during gestation on prenatal-stressed offspring to that of environmental enrichment after weaning. Our results showed that environmental enrichment during gestation partially prevented anxiety and the damage in learning and memory in prenatal-stressed offspring as evaluated by elevated plus-maze test and Morris water maze test. At the same time, environmental enrichment during gestation inhibited the decrease in spine density of CA1 and dentate gyrus neurons and preserved the expression of synaptophysin and glucocorticoid receptors (GRs) in the hippocampus of prenatal-stressed offspring. There was no significant difference in offspring behavior between 7-day environmental enrichment during gestation and 14-day offspring environmental enrichment after weaning. These data suggest that environmental enrichment during gestation effectively prevented the behavior deficits and the abnormal synapse structures in prenatal-stressed offspring, and that it can be used as an efficient preventive strategy against prenatal stresses

  7. How is uranium supply affecting enrichment?

    International Nuclear Information System (INIS)

    Steve Kidd

    2007-01-01

    As a result of the enlivened uranium market, momentum has in turn picked up in the enrichment sector. What are the consequences of higher uranium prices? There is, of course, a link between uranium and enrichment supply to the extent that they are at least partial substitutes. On the enrichment supply side, the most obvious feature is the gradual replacement of the old gas diffusion facilities of Usec in the USA and EURODIF in France with more modern and economical centrifuge plants. Assuming Usec can overcome the financing and technical issues surrounding its plans, the last gas diffusion capacity should disappear around 2015 and the entire enrichment market should then be using centrifuges. On the commercial side, the key anticipated developments are mostly in Russia. Although there should still continue to be substantial quantities of surplus Russian HEU available for down blending in the period beyond 2013, it is now reasonable to expect that it will be mostly consumed by internal needs, to fuel Russian-origin reactors both at home and in export markets such as China and India. Finally, as a key sensitive area for the non-proliferation of nuclear weapons, the enrichment sector is likely to be a central point of the new international arrangements which must be developed to support a buoyant nuclear sector throughout this century.

  8. Effect of spermidine in PC12 cells on the cell apoptosis induced by enriched uranium

    International Nuclear Information System (INIS)

    Gu Guixiong; Zhu Shoupeng; Wang Liuyi; Yang Shuqin; Zhu Lingli

    2003-01-01

    This is a study on injurious effects of cellular spermidine to PC12 cells irradiated by enriched uranium. PC12 cells were cultured in DMEM/F12 medium with enriched uranium, and the exposure doses were calculated. The contents of free spermidine PC12 cells were examined with Dansyl-chloride reaction and thin-layer chromatography. Viability of the cells treated with enriched uranium reduced rapidly and DNA strand break increased significantly with increasing time of the irradiation. Autoradiographic tracks showed that the radionuclide located in the nucleus predominantly. The content of free spermidine in PC12 cells could markedly decrease as the irradiation time increased. The results suggested that PC12 cells exposured to enriched uranium were apoptotic and the free spermidine in cells might play some role in this process

  9. Environmentally enriched male mink gain more copulations than stereotypic, barren-reared competitors.

    Directory of Open Access Journals (Sweden)

    María Díez-León

    Full Text Available Wild carnivores in zoos, conservation breeding centres, and farms commonly live in relatively small, unstimulating enclosures. Under these captive conditions, in a range of species including giant pandas, black-footed ferrets, and European mink, male reproductive abilities are often poor. Such problems have long been hypothesized to be caused by these animals' housing conditions. We show for the first time that rearing under welfare-improving (i.e., highly valued and stress-reducing environmental enrichments enhances male carnivores' copulatory performance: in mate choice competitions, enriched male American mink (Neovison vison mated more often than non-enriched males. We screened for several potential mediators of this effect. First was physiological stress and its impact on reproductive physiology; second, stress-mediated changes in morphology and variables related to immunocompetence that could influence male attractiveness; and third, behavioural changes likely to affect social competence, particularly autistic-like excessive routine and repetition ('perseveration' as is reflected in the stereotypies common in captive animals. Consistent with physiological stress, excreted steroid metabolites revealed that non-enriched males had higher cortisol levels and lower androgen levels than enriched conspecifics. Their os penises (bacula also tended to be less developed. Consistent with reduced attractiveness, non-enriched males were lighter, with comparatively small spleens and a trend to greater fluctuating asymmetry. Consistent with impaired social competence, non-enriched males performed more stereotypic behaviour (e.g., pacing in their home cages. Of all these effects, the only significant predictor of copulation number was stereotypy (a trend suggesting that low bodyweights may also be influential: highly stereotypic males gained the fewest copulations. The neurophysiological changes underlying stereotypy thus handicap males sexually. We

  10. Permeation of iodide from iodine-enriched yeast through porcine intestine.

    Science.gov (United States)

    Ryszka, Florian; Dolińska, Barbara; Zieliński, Michał; Chyra, Dagmara; Dobrzański, Zbigniew

    2013-01-01

    Iodine deficiency is a common phenomenon, threatening the whole global human population. Recommended daily intake of iodine is 150 μg for adults and 250 μg for pregnant and breastfeeding women. About 50% of human population can be at risk of moderate iodine deficiency. Due to this fact, increased iodine supplementation is recommended, through intake of iodized mineral water and salt iodization. The aim of this study was to investigate permeation and absorption of iodide from iodine bioplex (experimental group) in comparison with potassium iodide (controls). Permeation and absorption processes were investigated in vitro using a porcine intestine. The experimental model was based on a standard Franz diffusion cell (FD-Cell). The iodine bioplex was produced using Saccharomyces cerevisiae yeast and whey powder: iodine content - 388 μg/g, total protein - 28.5%, total fat - 0.9%., glutamic acid - 41.2%, asparaginic acid - 29.4%, lysine - 24.8%; purchased from: F.Z.N.P. Biochefa, Sosnowiec, Poland. Potassium iodide was used as controls, at 388 μg iodine concentration, which was the same as in iodine-enriched yeast bioplex. A statistically significant increase in iodide permeation was observed for iodine-enriched yeast bioplex in comparison with controls - potassium iodide. After 5h the total amount of permeated iodide from iodine-enriched yeast bioplex was 85%, which is ~ 2-fold higher than controls - 37%. Iodide absorption was by contrast statistically significantly higher in controls - 7.3%, in comparison with 4.5% in experimental group with iodine-enriched yeast bioplex. Presented results show that iodide permeation process dominates over absorption in case of iodine-enriched yeast bioplex.

  11. Preservation of microbial communities enriched on lignocellulose under thermophilic and high-solid conditions.

    Science.gov (United States)

    Yu, Chaowei; Reddy, Amitha P; Simmons, Christopher W; Simmons, Blake A; Singer, Steven W; VanderGheynst, Jean S

    2015-01-01

    Microbial communities enriched from diverse environments have shown considerable promise for the targeted discovery of microorganisms and enzymes for bioconversion of lignocellulose to liquid fuels. While preservation of microbial communities is important for commercialization and research, few studies have examined storage conditions ideal for preservation. The goal of this study was to evaluate the impact of preservation method on composition of microbial communities enriched on switchgrass before and after storage. The enrichments were completed in a high-solid and aerobic environment at 55 °C. Community composition was examined for each enrichment to determine when a stable community was achieved. Preservation methods included cryopreservation with the cryoprotective agents DMSO and glycerol, and cryopreservation without cryoprotective agents. Revived communities were examined for their ability to decompose switchgrass under high-solid and thermophilic conditions. High-throughput 16S rRNA gene sequencing of DNA extracted from enrichment samples showed that the majority of the shift in composition of the switchgrass-degrading community occurred during the initial three 2-week enrichments. Shifts in community structure upon storage occurred in all cryopreserved samples. Storage in liquid nitrogen in the absence of cryoprotectant resulted in variable preservation of dominant microorganisms in enriched samples. Cryopreservation with either DMSO or glycerol provided consistent and equivalent preservation of dominant organisms. A stable switchgrass-degrading microbial community was achieved after three 2-week enrichments. Dominant microorganisms were preserved equally well with DMSO and glycerol. DMSO-preserved communities required more incubation time upon revival to achieve pre-storage activity levels during high-solid thermophilic cultivation on switchgrass. Despite shifts in the community with storage, the samples were active upon revival under thermophilic and

  12. Toward a predictive theory for environmental enrichment.

    Science.gov (United States)

    Watters, Jason V

    2009-11-01

    There have been many applications of and successes with environmental enrichment for captive animals. The theoretical spine upon which much enrichment work hangs largely describes why enrichment should work. Yet, there remains no clear understanding of how enrichment should be applied to achieve the most beneficial results. This lack of understanding may stem in part from the assumptions that underlie the application of enrichment by practitioners. These assumptions are derived from an understanding that giving animals choice and control in their environment stimulates their motivation to perform behaviors that may indicate a heightened state of well-being. Learning theory provides a means to question the manner in which these constructs are routinely applied, and converting learning theory's findings to optimality predictions suggests a particularly vexing paradox-that motivation to perform appears to be maintained best when acquiring a payoff for expressing the behavior is uncertain. This effect occurs even when the actual value of the payoff is the same for all schedules of certainty of payoff acquisition. The paradox can be resolved by invoking rewards of an alternative type, such as cognitive rewards, or through an understanding of how the average payoff changes with changes in the probability of reward. This model, with measures of the average change of the payoff, suggests testable scenarios by which practitioners can measure the quality of environmental uncertainty in enrichment programs.

  13. Oak Ridge National Laboratory's isotope enrichment program

    International Nuclear Information System (INIS)

    Tracy, J.G.; Aaron, W.C.

    1997-01-01

    The Isotope Enrichment Program (IEP) at Oak Ridge National Laboratory (ORNL) is responsible for the production and distribution of ∼225 enriched stable isotopes from 50 multi-isotopic elements. In addition, ORNL distributes enriched actinide isotopes and provides extensive physical- and chemical-form processing of enriched isotopes to meet customer requirements. For more than 50 yr, ORNL has been a major provider of enriched isotopes and isotope-related services to research, medical, and industrial institutions throughout the world. Consolidation of the Isotope Distribution Office (IDO), the Isotope Research Materials Laboratory (IRML), and the stable isotope inventories in the Isotope Enrichment Facility (IEF) have improved operational efficiencies and customer services. Recent changes in the IEP have included adopting policies for long-term contracts, which offer program stability and pricing advantages for the customer, and prorated service charges, which greatly improve pricing to the small research users. The former U.S. Department of Energy (DOE) Loan Program has been converted to a lease program, which makes large-quantity or very expensive isotopes available for nondestructive research at a nominal cost. Current efforts are being pursued to improve and expand the isotope separation capabilities as well as the extensive chemical- and physical-form processing that now exists. The IEF's quality management system is ISO 9002 registered and accredited in the United States, Canada, and Europe

  14. Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion.

    Science.gov (United States)

    Zhong, Zhenyu; Rosenow, Matthew; Xiao, Nick; Spetzler, David

    2018-01-01

    Extracellular vesicle (EV)-based liquid biopsies have been proposed to be a readily obtainable biological substrate recently for both profiling and diagnostics purposes. Development of a fast and reliable preparation protocol to enrich such small particles could accelerate the discovery of informative, disease-related biomarkers. Though multiple EV enrichment protocols are available, in terms of efficiency, reproducibility and simplicity, precipitation-based methods are most amenable to studies with large numbers of subjects. However, the selectivity of the precipitation becomes critical. Here, we present a simple plasma EV enrichment protocol based on pluronic block copolymer. The enriched plasma EV was able to be verified by multiple platforms. Our results showed that the particles enriched from plasma by the copolymer were EV size vesicles with membrane structure; proteomic profiling showed that EV-related proteins were significantly enriched, while high-abundant plasma proteins were significantly reduced in comparison to other precipitation-based enrichment methods. Next-generation sequencing confirmed the existence of various RNA species that have been observed in EVs from previous studies. Small RNA sequencing showed enriched species compared to the corresponding plasma. Moreover, plasma EVs enriched from 20 advanced breast cancer patients and 20 age-matched non-cancer controls were profiled by semi-quantitative mass spectrometry. Protein features were further screened by EV proteomic profiles generated from four breast cancer cell lines, and then selected in cross-validation models. A total of 60 protein features that highly contributed in model prediction were identified. Interestingly, a large portion of these features were associated with breast cancer aggression, metastasis as well as invasion, consistent with the advanced clinical stage of the patients. In summary, we have developed a plasma EV enrichment method with improved precipitation selectivity

  15. The isotopic enrichment of uranium in 1979

    International Nuclear Information System (INIS)

    Baron, M.

    1979-01-01

    The Eurodif uranium enrichment plant built on the Tricastin site is described. The uranium isotope separation plants in service abroad are presented. The main characteristics of the international enrichment market are defined [fr

  16. Early enrichment in free-range laying hens: effects on ranging behaviour, welfare and response to stressors.

    Science.gov (United States)

    Campbell, D L M; Hinch, G N; Downing, J A; Lee, C

    2018-03-01

    Free-range laying hen systems are increasing within Australia. The pullets for these systems are typically reared indoors before being provided first range access around 21 to 26 weeks of age. Thus, the rearing and laying environments are disparate and hens may not adapt well to free-range housing. In this study, we reared 290 Hy-Line® Brown day-old chicks divided into two rooms each with feed, water and litter. In the enriched room, multiple structural, manipulable, visual and auditory stimuli were also provided from 4 to 21 days, the non-enriched room had no additional objects or stimuli. Pullets were transferred to the laying facility at 12 weeks of age and divided into six pens (three enriched-reared, three non-enriched-reared) with identical indoor resources and outdoor range area. All birds were first provided range access at 21 weeks of age. Video observations of natural disturbance behaviours on the range at 22 to 23 and 33 to 34 weeks of age showed no differences in frequency of disturbance occurrences between treatment groups (P=0.09) but a decrease in disturbance occurrences over time (Prange each day (Prange visits than non-enriched birds from 21 to 24 weeks of age (P=0.01). Enriched birds accessed the range on more days (P=0.03) but over time, most birds in both treatment groups accessed the range daily. Basic external health scoring showed minimal differences between treatment groups with most birds in visibly good condition. At 38 weeks of age all birds were locked inside for 2 days and from 40 to 42 weeks of age the outdoor range was reduced to 20% of its original size to simulate stressful events. The eggs from non-enriched birds had higher corticosterone concentrations following lock-in and 2 weeks following range reduction compared with the concentrations within eggs from enriched birds (Prange area reduction compared to non-enriched hens (P=0.02). Only one rearing room per treatment was used but these preliminary data indicate 3 weeks of early

  17. Bitcoin Meets Strong Consistency

    OpenAIRE

    Decker, Christian; Seidel, Jochen; Wattenhofer, Roger

    2014-01-01

    The Bitcoin system only provides eventual consistency. For everyday life, the time to confirm a Bitcoin transaction is prohibitively slow. In this paper we propose a new system, built on the Bitcoin blockchain, which enables strong consistency. Our system, PeerCensus, acts as a certification authority, manages peer identities in a peer-to-peer network, and ultimately enhances Bitcoin and similar systems with strong consistency. Our extensive analysis shows that PeerCensus is in a secure state...

  18. Separate enrichment analysis of pathways for up- and downregulated genes.

    Science.gov (United States)

    Hong, Guini; Zhang, Wenjing; Li, Hongdong; Shen, Xiaopei; Guo, Zheng

    2014-03-06

    Two strategies are often adopted for enrichment analysis of pathways: the analysis of all differentially expressed (DE) genes together or the analysis of up- and downregulated genes separately. However, few studies have examined the rationales of these enrichment analysis strategies. Using both microarray and RNA-seq data, we show that gene pairs with functional links in pathways tended to have positively correlated expression levels, which could result in an imbalance between the up- and downregulated genes in particular pathways. We then show that the imbalance could greatly reduce the statistical power for finding disease-associated pathways through the analysis of all-DE genes. Further, using gene expression profiles from five types of tumours, we illustrate that the separate analysis of up- and downregulated genes could identify more pathways that are really pertinent to phenotypic difference. In conclusion, analysing up- and downregulated genes separately is more powerful than analysing all of the DE genes together.

  19. Stereotypic behaviour in standard non-enriched cages is an alternative to depression-like responses in C57BL/6 mice.

    Science.gov (United States)

    Fureix, Carole; Walker, Michael; Harper, Laura; Reynolds, Kathryn; Saldivia-Woo, Amanda; Mason, Georgia

    2016-05-15

    Depressive-like forms of waking inactivity have been recently observed in laboratory primates and horses. We tested the hypotheses that being awake but motionless within the home-cage is a depression-like symptom in mice, and that in impoverished housing, it represents an alternative response to stereotypic behaviour. We raised C57BL/6 ('C57') and DBA/2 ('DBA') females to adulthood in non-enriched (n=62 mice) or enriched (n=60 mice) cages, observing home-cage behaviour during the active (dark) phases. We predicted that being still but awake would be reduced by environmental enrichment; more pronounced in C57s, as the strain most prone to learned helplessness; negatively related to stereotypic behaviour; and positively related to immobility in Forced Swim Tests (FST). Compared to enriched mice, non-enriched subjects did spend more time spent being inactive but awake, especially if they displayed relatively little stereotypic behaviour. C57 mice also spent more time awake but motionless than DBAs. Furthermore, even after statistically controlling for housing type and strain, this behaviour very strongly tended to predict increased immobility in the FST, while high levels of stereotypic behaviours in contrast predicted low immobility in the FST. Being awake but motionless is thus a reaction to non-enriched housing that seems to be an alternative to stereotypic behaviour, and could reflect depression-like states. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. Method and apparatus for enrichment or upgrading heavy water

    International Nuclear Information System (INIS)

    Butler, J.P.; Hammerli, M.

    1979-01-01

    A method and apparatus for upgrading and final enrichment of heavy water are described, comprising means for contacting partially enriched heavy water feed in a catalyst column with hydrogen gas (essentially D 2 ) originating in an electrolysis cell so as to enrich the feed water with deuterium extracted from the electrolytic hydrogen gas and means for passing the deuterium enriched water to the electrolysis cell. (author)

  1. EURODIF: the uranium enrichment by gaseous diffusion

    International Nuclear Information System (INIS)

    Rougeau, J.P.

    1981-01-01

    During the seventies the nuclear power programme had an extremely rapid growth rate which entailed to increase the world uranium enrichment capacity. EURODIF is the largest undertaking in this field. This multinational joint venture built and now operates and enrichment plant using the gaseous diffusion process at Tricastin (France). This plant is delivering low enriched uranium since two years and has contracted about 110 million SWU's till 1990. Description, current activity and prospects are given in the paper. (Author) [pt

  2. Unattended safeguards instrumentation at centrifuge enrichment plants

    International Nuclear Information System (INIS)

    Smith, L. Eric; Lebrun, Alain R.; Labella, Rocco

    2014-01-01

    As global uranium enrichment capacity under international safeguards expands, the International Atomic Energy Agency (IAEA) is challenged to develop effective safeguards approaches at gaseous centrifuge enrichment plants, particularly high‑capacity plants, while working within budgetary constraints. New safeguards approaches should meet the high‑level verification objectives for such facilities (i.e., timely detection of: diversion of declared material, excess production beyond declared amounts, and production of enrichment levels higher than declared), but should also strive for efficiency advantages in implementation, for both the IAEA and operators. Under the Agency’s State- level approach to safeguards implementation, the Agency needs a flexible toolbox of technologies, allowing tailoring of safeguards measures for each individual enrichment facility. In this paper, the potential roles and development status for three different types of unattended measurement instrumentation are discussed. On‑Line Enrichment Monitors (OLEM) could provide continuous enrichment measurement for 100% of the declared gas flowing through unit header pipes. Unattended Cylinder Verification Stations (UCVS) could provide unattended verification of the declared uranium mass and enrichment of 100% of the cylinders moving through the plant, but also apply and verify an ‘NDA Fingerprint’ to preserve verification knowledge on the contents of each cylinder throughout its life in the facility. Sharing of the operator’s load cell signals from feed and withdrawal stations could count all cylinders introduced to the process and provide periodic monitoring of the uranium mass balance for in‑process material. The integration of load cell, OLEM and UCVS data streams offers the possibility for 100% verification of declared cylinder flow, and enables the periodic verification of the declared 235 U mass balance in the plant. These new capabilities would enhance the IAEA

  3. Search for biological effects of 13C-enrichment in developing mammalian systems

    International Nuclear Information System (INIS)

    Gregg, C.; Ott, D.; Deaven, L.; Spielmann, H.; Krowke, R.; Neubert, D.

    1975-01-01

    Increasing diagnostic use of stable isotopes, especially in children and pregnant women, enhances the importance of studies on the biological isotope effects in sensitive mammalian systems. Experimental data on animal systems are meager. The mouse embryos was studied at various stages and mouse limb buds were studied in organ culture. Limb bud development in vitro was unaffected by incubation with 82 mol percent 13 C-glucose as judged by either morphological or biochemical criteria. Of 271 preimplantation embryos incubated in vitro, 95.2 percent developed normally; in 13 C-enriched medium, 96.5 percent showed normal development. 13 C-Enrichment of the embryos in vitro is over 60 percent. Administration of 1.2 g glucose-U- 13 C to pregnant mice during organogenesis leads to enrichment of maternal liver glycogen to over 17 mol percent 13 C, about one-third this level in the embryo, and a lower level in maternal blood. The absolute 13 C content of the embryo continues to increase for several days after the end of isotope administration, while the enrichment in maternal tissues falls. The lipid fraction of the fetus is most highly labeled shortly after the end of isotope administration []These studies on developing mammalian systems have not yet revealed any alteration of normal development due to stable isotope enrichment. (auth)

  4. Curriculum enrichment through indigenous Zulu games | Roux ...

    African Journals Online (AJOL)

    Curriculum enrichment through indigenous Zulu games. ... 1997). The aim of the study was to document and analyze indigenous Zulu games for possible curriculum enrichment of physical ... AJOL African Journals Online. HOW TO USE AJOL.

  5. Unjust enrichment in business law

    OpenAIRE

    Vydrová, Zuzana

    2016-01-01

    This thesis analyses the concept of unjust enrichment under the business law. First of all the thesis explains the term of business law. Business law is a complex of legal rules concerning the contractual relationships between entrepreneurs arising from their business activities. Business law is a comprehensive field of law which extends into many other fields of law, both private and public law. Equally the regulation of unjust enrichment within the business law expands into many other laws ...

  6. The interplay among prey preference, nutrient enrichment and stability in an omnivory system

    Directory of Open Access Journals (Sweden)

    LDB. Faria

    Full Text Available Food webs usually display an intricate mix of trophic interactions where multiple prey are common. In this context omnivory has been the subject of intensive analysis regarding food web stability and structure. In a three species omnivory setting it is shown that the modeling of prey preference by the top predator may exert a strong influence on the short as well as on the long term dynamics of the respective food web. Clearly, this has implications concerning the stability and the structure of omnivory systems under disturbances such as nutrient enrichment.

  7. Uranium enrichment by centrifuge in Japan

    International Nuclear Information System (INIS)

    Watanabe, T.; Murase, T.

    1977-01-01

    The demand for enriched uranium is on the increase with nuclear power capacity in which the LWR predominates and is estimated to exceed the supply from the present facilities in the world in less than ten years. Therefore, the basic strategy for enriched uranium is investigated on the following three-point long-range program in Japan: 1. To continue negotiations to extend the current allocation by the long-term contract; 2. To seek active participation in international enrichment projects; and 3. To make efforts to develop uranium enrichment technology and to construct inland facilities. On this basis, a vigorous development program of gas centrigue process for industrialization was launched out in 1972 as a national project. Ever since substantial progress in this field has been made and development works have been increased year after year. At present, a concrete plan of a pilot plant is taking shape. Up to now, several types of centrifuges were developed, of which some were completed as prototype models, and subjected to life tests and also to extensive earthquake-resistivity tests for the characteristics of Japanese geological condition. An enrichment plant is composed of so many centrifuges that the installation and piping system of centrifuges is an important factor which has an effect on plant economy and reliability. Two types of the experimental cascade were constructed in Japan. One has been in operation since 1973, and the other since 1975. Valuable empirical data have been accumulated on cascade characteristics, maintenance scheme and so on. It will be important for the coming plants to have a flexibility to escalation of labor and energy cost, or to variation of the separative work requirement and further. An economic prospect of centrifuge enrichment process is presented

  8. Enrichment of Biscuits with Matcha Green Tea Powder: Its Impact on Consumer Acceptability and Acute Metabolic Response

    Directory of Open Access Journals (Sweden)

    Benjapor Phongnarisorn

    2018-02-01

    Full Text Available Matcha green tea powder (MGTP is made with finely ground green tea leaves that are rich in phytochemicals, most particularly catechins. Shortbread biscuits were enriched with MGTP and evaluated for consumer acceptability and potential functional health properties. Baking decreased the content of total catechins by 19% compared to dough, although epimerization increased the amount of (+-gallocatechin gallate at the expense of other catechins such as (−-epigallocatechin gallate. Consumer acceptability tests using a 9-point hedonic scale showed that consumers preferred enriched biscuits with low content of MGTP (2 g of MGTP 100 g−1 of flour, and an increase of sugar content did not significantly improve the acceptability of MGTP-enriched biscuits. Overall, enrichment of biscuits with MGTP did not significantly affect the postprandial glucose or triglyceride response (area under curve compared to non-enriched biscuits consumed with water or MGTP drink. Enriching biscuits with Matcha green tea is acceptable to consumers, but may not bring significant postprandial effects.

  9. US enrichment reduction studies

    International Nuclear Information System (INIS)

    1979-06-01

    A major national program, the Reduced Enrichment Research and Test Reactor (RERTR) Program, is currently under way in the U.S., centered at the Argonne National Laboratory (ANL), to reduce the potential of research and test reactor fuels for increasing the proliferation of nuclear explosive devices. The main objective of the program is to provide the technical means by which the uranium enrichment to be used in these reactors can be reduced to less than 20% without significant economic and performance penalties. The criteria, basis and goals of the program are consistent with the results of a number of case studies which have been performed as part of the program

  10. Advanced uranium enrichment processes

    International Nuclear Information System (INIS)

    Clerc, M.; Plurien, P.

    1986-01-01

    Three advanced Uranium enrichment processes are dealt with in the report: AVLIS (Atomic Vapour LASER Isotope Separation), MLIS (Molecular LASER Isotope Separation) and PSP (Plasma Separation Process). The description of the physical and technical features of the processes constitutes a major part of the report. If further presents comparisons with existing industrially used enrichment technologies, gives information on actual development programmes and budgets and ends with a chapter on perspectives and conclusions. An extensive bibliography of the relevant open literature is added to the different subjects discussed. The report was drawn up by the nuclear research Centre (CEA) Saclay on behalf of the Commission of the European Communities

  11. Low-resolution gamma-ray measurements of uranium enrichment

    International Nuclear Information System (INIS)

    Sprinkle, J.K. Jr.; Christiansen, A.; Cole, R.; Collins, M.L.

    1996-01-01

    Facilities that process special nuclear material perform periodic inventories. In bulk facilities that process low-enriched uranium, these inventories and their audits are based primarily on weight and enrichment measurements. Enrichment measurements determine the 211 U weight fraction of the uranium compound from the passive gamma-ray emissions of the sample. Both international inspectors and facility operators rely on the capability to make in-field gamma-ray measurements of uranium enrichment. These users require rapid, portable measurement capability. Some in-field measurements have been biased, forcing the inspectors to resort to high-resolution measurements or mass spectrometry to accomplish their goals

  12. A consideration on laser enrichment module

    International Nuclear Information System (INIS)

    Arisawa, Takashi; Shiba, Koreyuki

    1983-09-01

    Several problems are discussed for designing a simplified enrichment module based on Atomic Laser Isotope Separation Method, which involve the vaporization of metal, laser excitation, laser ionization and ion recovery. The conditions at which the consumed energy has the minimum value are obtained by calculating the specific energy consumption for producing unit amount of enriched products. It is found that there should be an appropriate relationship between the processing atomic density and the electrode gap in order to avoid the enrichment loss caused by the charge exchange during the ion recovery. Moreover it is also found that this relation depends on the electrode length measured along both the atomic beam direction and the laser beam direction. (author)

  13. Enrichment of Phenolic Compounds from Olive Mill Wastewater and In Vitro Evaluation of Their Antimicrobial Activities

    Directory of Open Access Journals (Sweden)

    Saleh Abu-Lafi

    2017-01-01

    Full Text Available The production of olive oil generates massive quantities of by-product called olive mill wastewater (OMWW. The uncontrolled disposal of OMWW poses serious environmental problems. The OMWW effluent is rich in several polyphenolic compounds. Liquid-liquid extraction of OMWW using ethyl acetate solvent was used to enrich phenolic compounds under investigation. Total phenolic and flavonoid content and antioxidant activity of the extract were determined. HPLC coupled to photodiode array (PDA detector was used to analyze the main three phenolic compounds of OMWW, namely, hydroxytyrosol, tyrosol, and oleuropein. The antimicrobial activity of the extract was also investigated. Additionally, the OMWW extract was used as natural preservative and antioxidants for olive oil. Results showed that OMWW is very rich in phenolic compounds and has strong antioxidant activity. HPLC analysis showed that the extract contains mainly hydroxytyrosol and tyrosol but no oleuropein. The OMWW extract showed also positive activities as antibacterial (gram positive and gram negative and antifungal as well as activities against yeast. The addition of OMWW extract to olive oil samples has an effect on the stability of olive oil as reflected by its acid value, peroxide value, K232 and K270, and total phenolic content.

  14. 21 CFR 137.350 - Enriched rice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Enriched rice. 137.350 Section 137.350 Food and... Related Products § 137.350 Enriched rice. (a) The foods for which definitions and standards of identity are prescribed by this section are forms of milled rice (except rice coated with talc and glucose and...

  15. Tritium enrichment from aqueous solutions using cryosublimation of mono- and polysaccharides

    International Nuclear Information System (INIS)

    Wierczinski, B.; Muellen, G.; Rosenhauer, S.

    2008-01-01

    Cryosublimation is one technique, which allows the accumulation of tritium from aqueous solutions using certain chemical compounds. After studying several inorganic compounds such as zeolites and metal salts, as well as some humic substances, we have now investigated several mono- and polysaccharides, such as glucose, maltose, galactose, starch, agar, and gelatine. Except for starch all of the above mentioned compounds showed a clear enrichment of tritium. The highest value was reached for Agartine, which gave an enrichment factor of 6.2. Since mono- and polysaccharides form weak hydrogen bonds, these results prove again our theory that tritium is preferably accumulated in exchangeable hydrogen bonds. (author)

  16. Theoretical studies aiming at the IEA-R1 reactor core conversion from high U-235 enrichment to low U-235 enrichment

    International Nuclear Information System (INIS)

    Frajndlich, R.

    1982-01-01

    The research reactors, of which the fuel elements are of MTR type, functions presently, almost in their majority with high U-235 enrichment. The fear that those fuel elements might generate a considerabLe proliferation of nuclear weapons rendered almost mandatory the conversion of highly enriched fuel elements to a low U-235 enrichment. As the IEA-R1 reactor of IPEN is operating with highly enriched fuel elements a study aiming at this conversion was done. The problems related to the conversion and the results obtained, demonstrated the technical viabilty for its realization. (E.G.) [pt

  17. Analysis Of The Effect Of Fuel Enrichment Error On Neutronic Properties Of The RSG-GAS Core

    International Nuclear Information System (INIS)

    Saragih, Tukiran; Pinem, Surian

    2002-01-01

    The analysis of the fuel enrichment error effect on neutronic properties has been carried out. The fuel enrichment could be improperly done because of wrong fabrication. Therefore it is necessary to analyze the fuel enrichment error effect to determine how many percents the fuel enrichment maximum can be accepted in the core. The analysis was done by simulation method The RSG-GAS core was simulated with 5 standard fuels and 1 control element having wrong enrichment when inserted into the core. Fuel enrichment error was then simulated from 20%, 25% and 30% and the simulation was done using WIMSD/4 and Batan-2DIFF codes. The cross section of core material of the RSG-GAS was generated by WIMSD/4 code in 1-D, X-Y geometry and 10 energy neutron group. Two dimensions, diffusion calculation based on finite element method was done by using Batan-2DIFF code. Five fuel elements and one control element changed the enrichment was finally arranged as a new core of the RSG-Gas reactor. The neutronic properties can be seen from eigenvalues (k eff ) as well as from the kinetic properties based on moderator void reactivity coefficient. The calculated results showed that the error are still acceptable by k eff 1,097 even until 25% fuel enrichment but not more than 25,5%

  18. Indices, multispecies and synthesis descriptors in benthic assessments: Intertidal organic enrichment from oyster farming

    Science.gov (United States)

    Quintino, Victor; Azevedo, Ana; Magalhães, Luísa; Sampaio, Leandro; Freitas, Rosa; Rodrigues, Ana Maria; Elliott, Michael

    2012-09-01

    Intertidal off-bottom oyster culture is shown to cause organic enrichment of the shore and although there are two stressors of interest (the presence of a structure, the trestles, and also the sediment and organic waste from the oysters), these can be separated and their relative impacts determined using an appropriate nested experimental design and data treatments. Although no artificial food sources are involved, the oysters feeding activity and intensity of culture enhances biodeposition and significantly increases the sediment fines content and total organic matter. This in general impoverished the benthic community in culture areas rather than a species succession with the installation of opportunists or a resulting increase in the abundance and biomass of benthic species; the findings can be a direct consequence of the intertidal situation which is less-amenable recruitment of species more common to the subtidal environment. Thus the most appropriate biological descriptors to diagnose the effects associated with the organic enrichment were the multispecies abundance data as well as the primary biological variables species richness and abundance. The effects were however spatially and statistically significantly confined to the area located directly underneath the culture bags compared to the corridors located between the trestles, which do not show such enrichment effects. Synthesis biotic indices were much less effective to diagnose the benthic alterations associated with this organic enrichment. These results show that special attention must be paid when using indices in areas where the organic enrichment induces an impoverishment of the benthic community but not necessarily a species replacement with the installation of opportunists.

  19. Enriched environment palliates nicotine-induced addiction and associated neurobehavioral deficits in rats.

    Science.gov (United States)

    Nawaz, Amber; Batool, Zehra; Ahmed, Saara; Tabassum, Saiqa; Khaliq, Saima; Mehdi, Bushra Jabeen; Sajid, Irfan; Ahmad, Shoaib; Saleem, Sadia; Naqvi, Fizza; Naqvi, Faizan; Haider, Saida

    2017-11-01

    This study was designed to investigate the role of enriched environment in preventing and/or reducing the neurobehavioral deficits produced after nicotine administration in albino Wistar rats. Equal numbers of rat in two groups were either placed in social environment (control group) or social along with physically enriched environment for four weeks before the administration of nicotine. Exposure to different environmental conditions was followed by the intraperitoneal injection of nicotine at the dose of 0.6 mg/kg for seven consecutive days during which addictive behavior was monitored using conditioned placed preference paradigm. Behavioral responses to locomotor activity, anxiety and retention of short term memory were investigated in control and nicotine injected groups exposed to different environments. Results of this study showed that the rats pre-exposed to physical along with social enrichment exhibited a decrease in drug seeking behavior, hyper locomotion, anxiogenic effects along with improvement of working memory as compared to control and nicotine injected groups that were kept in social environment alone. This behavioral study suggests that the exposure to physical enrichment along with socialization in young age can later reduce the chances of compulsive dependence on nicotine and related neurobehavioral deficits.

  20. Axial blanket enrichment optimization of the NPP Krsko fuel

    International Nuclear Information System (INIS)

    Kromar, M.; Kurincic, B.

    2001-01-01

    In this paper optimal axial blanket enrichment of the NPP Krsko fuel is investigated. Since the optimization is dictated by economic categories that can significantly vary in time, two step approach is applied. In the first step simple relationship between the equivalent change in enrichment of axial blankets and central fuel region is established. The relationship is afterwards processed with economic criteria and constraints to obtain optimal axial blanket enrichment. In the analysis realistic NPP Krsko conditions are considered. Except for the fuel enrichment all other fuel characteristics are the same as in the fuel used in the few most recent cycles. A typical reload cycle after the plant power uprate is examined. Analysis has shown that the current blanket enrichment is close to the optimal. Blanket enrichment reduction results in an approximately 100 000 US$ savings per fuel cycle.(author)

  1. Positive responses of belowground C dynamics to nitrogen enrichment in China.

    Science.gov (United States)

    Deng, Lei; Peng, Changhui; Zhu, Guangyu; Chen, Lei; Liu, Yulin; Shangguan, Zhouping

    2018-03-01

    Determining how nitrogen (N) impacts ecosystem carbon (C) cycling is critical to using C sequestration to offset anthropogenic CO 2 emissions. The N deposition rate in China is higher than the global average; however, many results of N enrichment experiments in China have not been included in global syntheses. In this study, we assembled a large dataset that comprised 124 published studies concerning N addition experiments, including 570 observations at 127 sites across China, to quantify the responses of belowground C dynamics to N enrichment in terrestrial ecosystems in China by a meta-analysis. The results showed that overall soil organic C, dissolved organic C (DOC) and soil microbial biomass C (MBC) increased by 1.8, 7.4, and 8.8%, respectively (Penrichment; belowground biomass and litter increased by 14.6 and 24.4%, respectively (Penrichment promoted C inputs into the soil mainly by increasing litter and belowground biomass inputs. Additionally, N enrichment increased C output by increasing soil respiration. Land use type and N addition level had different impacts on the soil C pool and on soil respiration. DOC, MBC, and litter exhibited more positive responses to N deposition in cooler and more arid regions than in other regions. The meta-analysis indicated that N enrichment had a positive impact on belowground C cycles in China. Climate played a greater role than did N deposition level in affecting processes of ecosystem C cycling. Moreover, belowground C cycle processes are determined by complicated interactions among land use type, N enrichment, and climate. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Stability and bioaccessibility of anthocyanins in bakery products enriched with anthocyanins.

    Science.gov (United States)

    Karakaya, Sibel; Simsek, Sebnem; Eker, Alper Tolga; Pineda-Vadillo, Carlos; Dupont, Didier; Perez, Beatriz; Viadel, Blanca; Sanz-Buenhombre, Marisa; Rodriguez, Alberto Guadarrama; Kertész, Zsófia; Hegyi, Adrienn; Bordoni, Alessandra; El, Sedef Nehir

    2016-08-10

    Anthocyanins, water soluble polyphenols, have been associated with several beneficial health effects. The aim of this study was to determine how the baking process and food matrix affect anthocyanin stability and bioaccessibility in bakery products in order to develop functional foods. Three well known regularly consumed bakery products (buns, breadsticks and biscuits) were enriched with anthocyanin (AC) isolated from grape skin alone or in combination with docosahexaenoic acid (AC + DHA) to reveal knowledge on AC as active ingredients in real food systems rather than pure compounds. Anthocyanin amounts added to the formulations of buns, breadsticks and biscuits were 34 mg per 100 g, 40 mg per 100 g and 37 mg per 100 g, respectively. The effect of processing, storage and the food matrix on AC stability and bioaccessibility was investigated. In addition, the sensory properties of bakery products were evaluated. Breadsticks enriched with AC and AC + DHA received the lowest scores in the pre-screening sensory test. Therefore breadsticks were excluded from further analysis. AC retentions, which were monitored by determination of malvidin 3-O-glucoside, in the bun and biscuit after baking were 95.9% (13.6 mg per 100 g) and 98.6% (15.2 mg per 100 g), respectively. Biscuits and buns enriched only with AC showed significantly higher anthocyanin bioaccessibilities (57.26% and 57.30%, respectively) than the same ones enriched with AC + DHA. AC stability in enriched products stored for 21 days was significantly lower than in products stored for 7 days (p products.

  3. Study on the retention of enriched UO2F2 in the mouse and its radiogenotoxicological effects

    International Nuclear Information System (INIS)

    Hu Qiyue; Zhu Shoupeng

    1991-06-01

    The study on toxicological effects of enriched UO 2 F 2 was undertaken in purebred BALB/c male mice to examine: (a) the retention in body; (b) the testicular clearance; (c) the effect of sperm abnormality; (d) the effect of chromosomal aberrations in spermatogonia and primary spermatocytes; and (e) the effect of DNA damage in germ cells in various spermiogenic stages. Results show that enriched UO 2 F 2 mainly deposited in the kidneys, then the skeleton and liver. The amount of enriched UO 2 F 2 depositing in other tissues was small. Enriched UO 2 F 2 was similar to the natural uranium in transference and retention in the body. The testis had efficient clearance of enriched UO 2 F 2 . Enriched UO 2 F 2 could result in sperm abnormality. Even with the same treating does but at different treating time the rates of sperm abnormality were different. Enriched UO 2 F 2 could result in chromosomal aberrations in spermatogonia and primary spermatocytes. The important type of aberrations in spermatogonia was break. For primary spermatocytes the most significant aberration was multivalents. Enriched UO 2 F 2 could also result in DNA breakage in germ cells. The sensitivity of mouse germ cells at various stages to enriched UO 2 F 2 was different. There was a linear relationship between the amount of sperm DNA eluted and enriched UO 2 F 2 dose

  4. Gamma-ray measurements for uranium enrichment standards

    International Nuclear Information System (INIS)

    Reilly, T.D.

    1979-01-01

    The gamma-ray spectroscopic measurement of uranium enrichment is one of the most widely used nondestructive analysis techniques. A study has been started of the precision and accuracy achievable with this technique and the physical parameters which affect it. The study was prompted by questions raised during the ongoing ESARDA-NBS experiment to produce uranium oxide reference counting materials for the technique. Results reported using a high-quality Ge(Li) spectrometer system show reproducibility comparable to that attainable with mass spectrometry

  5. Enrichment of anaerobic syngas-converting bacteria from thermophilic bioreactor sludge.

    Science.gov (United States)

    Alves, Joana I; Stams, Alfons J M; Plugge, Caroline M; Alves, M Madalena; Sousa, Diana Z

    2013-12-01

    Thermophilic (55 °C) anaerobic microbial communities were enriched with a synthetic syngas mixture (composed of CO, H2 , and CO2 ) or with CO alone. Cultures T-Syn and T-CO were incubated and successively transferred with syngas (16 transfers) or CO (9 transfers), respectively, with increasing CO partial pressures from 0.09 to 0.88 bar. Culture T-Syn, after 4 successive transfers with syngas, was also incubated with CO and subsequently transferred (9 transfers) with solely this substrate - cultures T-Syn-CO. Incubation with syngas and CO caused a rapid decrease in the microbial diversity of the anaerobic consortium. T-Syn and T-Syn-CO showed identical microbial composition and were dominated by Desulfotomaculum and Caloribacterium species. Incubation initiated with CO resulted in the enrichment of bacteria from the genera Thermincola and Thermoanaerobacter. Methane was detected in the first two to three transfers of T-Syn, but production ceased afterward. Acetate was the main product formed by T-Syn and T-Syn-CO. Enriched T-CO cultures showed a two-phase conversion, in which H2 was formed first and then converted to acetate. This research provides insight into how thermophilic anaerobic communities develop using syngas/CO as sole energy and carbon source can be steered for specific end products and subsequent microbial synthesis of chemicals. © 2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

  6. Managing public acceptance for a new enrichment facility

    International Nuclear Information System (INIS)

    Boyd, M.

    1992-01-01

    The Claiborne Enrichment Center has many first associated with it, and a solid nuclear-based community relations experience has been combined with fly-by-the-seat-of-your-pants techniques to successfully introduce a first-of-a-kind facility not only to Louisiana, but also to the US. The project is being developed by Louisiana Energy Services (LES), a limited partnership consisting of Urenco, the European enrichment consortium that operates centrifuge enrichment facilities in the United Kingdom, the Netherlands, and Germany; Fluor Daniel, an internationally known engineering and construction firm; and three utilities - Duke Power, Northern States Power, and Louisiana Power and Light (LP and L). Louisiana Energy will build the nation's first privately owned uranium enrichment facility. It will be the first commercial use of centrifuge technology for enrichment in the US. Some of the community relations challenges the project has had and their solutions are described

  7. Olive oil enriched in lycopene from tomato by-product through a co-milling process.

    Science.gov (United States)

    Bendini, Alessandra; Di Lecce, Giuseppe; Valli, Enrico; Barbieri, Sara; Tesini, Federica; Toschi, Tullia Gallina

    2015-01-01

    The aim of this investigation was to produce an olive oil (OO) naturally enriched with antioxidants, recovering carotenoids, in particular lycopene, using an industrial by-product of tomato seeds and skin. For this purpose, a technological process in a low-scale industrial plant to co-mill olives and tomato by-product in de-frosted or freeze-dried forms was applied and studied with respect to control samples. Preliminary results obtained from two different experiments were carried out by 40 kg of cultivar Correggiolo olives and 60 kg of olive blends from different cultivars. In both the experiments, the co-milling showed significant enrichment in carotenoids, especially in lycopene (mean values of 5.4 and 7.2 mg/kg oil from defrosted and freeze-dried by-products, respectively). The experimental results demonstrated the possibility to obtain a new functional food naturally enriched in antioxidant compounds, which might be marketed as "OO dressing enriched in lycopene" or "condiment produced using olives and tomato by-product".

  8. Silica Retention and Enrichment in Open-System Chemical Weathering on Mars

    Science.gov (United States)

    Yen, A. S.; Ming, D. W.; Gellert, R.; Clark, B. C.; Mittlefehldt, D. W.; Morris, R. V.; Thompson, L. M.; Berger, J.

    2015-01-01

    Chemical signatures of weathering are evident in the Alpha Particle X-ray Spectrometer (APXS) datasets from Gusev Crater, Meridiani Planum, and Gale Crater. Comparisons across the landing sites show consistent patterns indicating silica retention and/or enrichment in open-system aqueous alteration.

  9. Fish burger enriched by olive oil industrial by-product.

    Science.gov (United States)

    Cedola, Annamaria; Cardinali, Angela; Del Nobile, Matteo Alessandro; Conte, Amalia

    2017-07-01

    Oil industry produces large volume of waste, which represents a disposal and a potential environmental pollution problem. Nevertheless, they are also promising sources of compounds that can be recovered and used as valuable substances. The aim of this work is to exploit solid olive by-products, in particular dry olive paste flour (DOPF) coming from Coratina cultivar, to enrich fish burger and enhance the quality characteristics. In particular, the addition of olive by-products leads to an increase of the phenolic content and the antioxidant activity; however, it also provokes a deterioration of sensory quality. Therefore, to balance quality and sensory characteristics of fish burgers, three subsequent phases have been carried out: first, the quality of DOPF in terms of phenolic compounds content and antioxidant activity has been assessed; afterward, DOPF has been properly added to fish burgers and, finally, the formulation of the enriched fish burgers has been optimized in order to improve the sensory quality. Results suggested that the enriched burgers with 10% DOPF showed considerable amounts of polyphenols and antioxidant activity, even though they are not very acceptable from the sensory point of view. Pre-treating DOPF by hydration/extraction with milk, significantly improved the burger sensory quality by reducing the concentration of bitter components.

  10. Environmental Enrichment Therapy for Autism: Outcomes with Increased Access

    Directory of Open Access Journals (Sweden)

    Eyal Aronoff

    2016-01-01

    Full Text Available We have previously shown in two randomized clinical trials that environmental enrichment is capable of ameliorating symptoms of autism spectrum disorder (ASD, and in the present study, we determined whether this therapy could be effective under real-world circumstances. 1,002 children were given daily Sensory Enrichment Therapy, by their parents, using personalized therapy instructions given over the Internet. Parents were asked to assess the symptoms of their child every 2 weeks for up to 7 months. An intention-to-treat analysis showed significant overall gains for a wide range of symptoms in these children, including learning, memory, anxiety, attention span, motor skills, eating, sleeping, sensory processing, self-awareness, communication, social skills, and mood/autism behaviors. The children of compliant caregivers were more likely to experience a significant improvement in their symptoms. The treatment was effective across a wide age range and there was equal progress reported for males and females, for USA and international subjects, for those who paid and those who did not pay for the therapy, and for individuals at all levels of initial symptom severity. Environmental enrichment, delivered via an online system, therefore appears to be an effective, low-cost means of treating the symptoms of ASD.

  11. BIOLOGICAL ACTIVITY OF APPLE JUICE ENRICHED BY HERBAL EXTRACTS

    Directory of Open Access Journals (Sweden)

    Eva Ivanišová

    2015-02-01

    Full Text Available Herbal phytochemicals have recently become an attractive subject for scientists in many different research areas. The aim of this study was to determine antioxidant activity, total polyphenol and flavonoid content of apple juice enriched by water herbal extracts. Secondary was to evaluate sensory characteristic of enriched apple juice. It was found that applications of water herbal extracts to apple juice increase antioxidant activities, and also total polyphenol and flavonoid content with compare to pure apple juice. The highest biological activities were detected in apple juice with addition of lemon balm (14.42 mg TEAC/L; 84.38 mg TEAC/L; 50.88 mg GAE/L; 36.26 μg QE/L, oregano (14.92 mg TEAC/L; 79.97 mg TEAC/L; 50.51 mg GAE/L; 31.02 μg QE/L and salvia (8.40 mg TEAC/L; 30.40 mg TEAC/L; 23.33 mg GAE/L; 27.67 μg QE/L water extract. Sensorial analysis of samples showed, that enriched juices had better properties for evaluators with compared to pure juice. The aim of this study was also to mention the potential use of medicinal herbs in food industry, because plant bioactive compounds can play an important role in preventing cardiovascular diseases, cancers and reduction inflammatory action.

  12. Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.

    Science.gov (United States)

    Broce, Iris; Karch, Celeste M; Wen, Natalie; Fan, Chun C; Wang, Yunpeng; Tan, Chin Hong; Kouri, Naomi; Ross, Owen A; Höglinger, Günter U; Muller, Ulrich; Hardy, John; Momeni, Parastoo; Hess, Christopher P; Dillon, William P; Miller, Zachary A; Bonham, Luke W; Rabinovici, Gil D; Rosen, Howard J; Schellenberg, Gerard D; Franke, Andre; Karlsen, Tom H; Veldink, Jan H; Ferrari, Raffaele; Yokoyama, Jennifer S; Miller, Bruce L; Andreassen, Ole A; Dale, Anders M; Desikan, Rahul S; Sugrue, Leo P

    2018-01-01

    show immune-mediated genetic enrichment specifically in FTD, particularly within the HLA region. Our genetic results suggest that for a subset of patients, immune dysfunction may contribute to FTD risk. These findings have potential implications for clinical trials targeting immune dysfunction in patients with FTD.

  13. Future of uranium enrichment

    International Nuclear Information System (INIS)

    Hosmer, C.

    1981-01-01

    The increasing amount of separative work being done in government facilities to produce low-enriched uranium fuel for nuclear utilities again raises the question: should this business-type, industrial function be burned over the private industry. The idea is being looked at by the Reagan administration, but faces problems of national security as well as from the unique nature of the business. This article suggests that a joint government-private venture combining enriching, reprocessing, and waste disposal could be the answer. Further, a separate entity using advanced laser technology to deplete existing uranium tails and lease them for fertile blankets in breeder reactors might earn substantial revenues to help reduce the national debt

  14. Uranium enrichment: investment options for the long term

    International Nuclear Information System (INIS)

    Anon.

    1983-01-01

    The US government supplies a major portion of the enriched uranium used to fuel most of the nuclear power plants that furnish electricity in the free world. As manager of the US uranium enrichment concern, the Department of Energy (DOE) is investigating a number of technological choices to improve enrichment service and remain a significant world supplier. The Congress will ultimately select a strategy for federal investment in the uranium enrichment enterprise. A fundamental policy choice between possible future roles - that of the free world's main supplier of enrichment services, and that of a mainly domestic supplier - will underlie any investment decision the Congress makes. The technological choices are gaseous diffusion, gas centrifuge, and atomic vapor laser isotope separation (AVLIS). A base plan and four alternatives were examined by DOE and the Congressional Budget Office. In terms of total enterprise costs, Option IV, ultimately relying on advanced gas centrifuges for enrichment services, would offer the most economic approach, with costs over the full projection period totaling $123.5 billion. Option III, ultimately relying on AVLIS without gas centrifuge enrichment or gaseous diffusion, falls next in the sequence, with costs of $128.2 billion. Options I and II, involving combinations of the gas centrifuge and AVLIS technologies, follow closely with costs of $128.7 and $129.6 billion. The base plan has costs of $136.8 billion over the projection period. 1 figure, 22 tables

  15. Environmental Enrichment for Broiler Breeders: An Undeveloped Field

    Directory of Open Access Journals (Sweden)

    Anja B. Riber

    2017-06-01

    Full Text Available Welfare problems, such as hunger, frustration, aggression, and abnormal sexual behavior, are commonly found in broiler breeder production. To prevent or reduce these welfare problems, it has been suggested to provide stimulating enriched environments. We review the effect of the different types of environmental enrichment for broiler breeders, which have been described in the scientific literature, on behavior and welfare. Environmental enrichment is defined as an improvement of the environment of captive animals, which increases the behavioral opportunities of the animal and leads to improvements in biological function. This definition has been broadened to include practical and economic aspects as any enrichment strategy that adversely affects the health of animals (e.g., environmental hygiene, or that has too many economic or practical constraints will never be implemented on commercial farms and thus never benefit animals. Environmental enrichment for broiler breeders often has the purpose of satisfying the behavioral motivations for feeding and foraging, resting, and/or encouraging normal sexual behavior. Potentially successful enrichments for broiler breeders are elevated resting places, cover panels, and substrate (for broiler breeders housed in cage systems. However, most of the ideas for environmental enrichment for broiler breeders need to be further developed and studied with respect to the use, the effect on behavior and welfare, and the interaction with genotype and production system. In addition, information on practical use and the economics of the production system is often lacking although it is important for application in practice.

  16. Measurement of the enrichment of uranium in the pipework of a gas centrifuge enrichment plant

    International Nuclear Information System (INIS)

    Packer, T.W.; Lees, E.W.; Close, D.; Nixon, K.V.; Pratt, J.C.; Strittmatter, R.

    1985-01-01

    The US and UK have been separately working on the development of a NDA instrument to determine the enrichment of gaseous UF 6 at low pressures in cascade header pipework in line with the conclusions of the Hexapartite Safeguards Project viz. the instrument is capable of making a ''go/no go'' decision of whether the enrichment is less than/greater than 20%. Recently, there has been a series of very useful technical exchanges of ideas and information between the two countries. This has led to a technical formulation for such an instrumentation based on γ-ray spectrometry which, although plant-specific in certain features, nevertheless is based on the same physical principles. Experimental results from commercially operating enrichment plants are very encouraging and indicate that a complete measurement including set up time on the pipe should be attainable in about 30 minutes when measuring pipes of diameter around 110 mm. 5 refs., 4 figs

  17. Yersinia enterocolitica in slaughter pig tonsils: enumeration and detection by enrichment versus direct plating culture.

    Science.gov (United States)

    Van Damme, Inge; Habib, Ihab; De Zutter, Lieven

    2010-02-01

    Tonsil samples from 139 slaughter pigs were examined for the presence of pathogenic Yersinia enterocolitica by enrichment procedures based on the standard method ISO 10273:2003. In addition, samples were tested by direct plating method to evaluate its efficiency compared to the enrichment culture methods and to quantify the level of contamination in porcine tonsils. In total, 52 samples (37.4%) were positive for pathogenic Y. enterocolitica, all belonging to bioserotype 4/O:3. Fifty out of the 52 positive samples (96.2%) were detected by direct plating. Enumeration showed an average concentration of 4.5 log(10) CFU g(-1) and 4.4 log(10) CFU g(-1) tonsil on Salmonella-Shigella-desoxycholate-calcium chloride (SSDC) and cefsulodin-irgasan-novobiocin (CIN) agar plates, respectively. The enrichment procedures recommended by the ISO 10273:2003 method were not optimal for the isolation of pathogenic Y. enterocolitica from pig tonsils: two days enrichment in irgasan-ticarcillin-potassium chlorate (ITC) broth resulted in an isolation rate of 84.6%, while 5 days enrichment in peptone-sorbitol-bile (PSB) broth recovered only 59.6% of positive samples. Reducing the enrichment time in PSB from 5 to 2 days resulted in a significantly higher recovery rate (94.2%) and might serve as an appropriate enrichment protocol for the isolation of pathogenic Y. enterocolitica from pig tonsils. Compared to enrichment culture methods, results based on direct plating can be obtained in a shorter time course and provide quantitative data that might be needed for further risk assessment studies.

  18. Applications and theory of electrokinetic enrichment in micro-nanofluidic chips.

    Science.gov (United States)

    Chen, Xueye; Zhang, Shuai; Zhang, Lei; Yao, Zhen; Chen, Xiaodong; Zheng, Yue; Liu, Yanlin

    2017-09-01

    This review reports the progress on the recent development of electrokinetic enrichment in micro-nanofluidic chips. The governing equations of electrokinetic enrichment in micro-nanofluidic chips are given. Various enrichment applications including protein analysis, DNA analysis, bacteria analysis, viruses analysis and cell analysis are illustrated and discussed. The advantages and difficulties of each enrichment method are expatiated. This paper will provide a particularly convenient and valuable reference to those who intend to research the electrokinetic enrichment based on micro-nanofluidic chips.

  19. Individual differences in the forced swimming test and the effect of environmental enrichment: searching for an interaction.

    Science.gov (United States)

    Sequeira-Cordero, A; Mora-Gallegos, A; Cuenca-Berger, P; Fornaguera-Trías, J

    2014-04-18

    Animals with low and high immobility in the forced swimming test (FST) differ in a number of neurobehavioral factors. A growing body of evidence suggests that the exposure to enriched environments mediates a number of changes in the brain. Therefore, we studied if animals' individuality can somehow modulate the response to environmental stimuli. Male rats were classified according to their immobility time scores in the FST test session as animals with low, medium or high immobility. Then, rats from groups with low and high immobility were randomly distributed in two groups to be reared in different housing conditions (i.e., enriched and standard conditions) during 8weeks. Animals were subjected to the open field test (OFT) before and 6weeks after the start of housing protocol. Rats with high immobility in the FST also showed high ambulation and high rearing time in the first OFT. Such findings were not observed in the second OFT. Conversely, an effect of environmental enrichment was found in the second OFT where enriched animals showed lower ambulation and higher grooming time than the standard control group. Rats were sacrificed after the housing protocol and neurochemical content and/or gene expression were studied in three different brain regions: the prefrontal cortex, the hippocampus and the nucleus accumbens. Rats with low immobility showed significantly higher accumbal 5-HT levels than animals with high immobility, whereas no neurochemical differences were observed between enriched and standard animals. Regarding expression data, however, an effect of enrichment on accumbal corticotropin-releasing factor (CRF) and its receptor 1 (CRFR1) levels was observed, and such effect depended on immobility levels. Thus, our results not only allowed us to identify a number of differences between animals with low and high immobility or animals housed in standard and enriched conditions, but also suggested that animals' individuality modulated in some way the response to

  20. Mowing exacerbates the loss of ecosystem stability under nitrogen enrichment in a temperate grassland.

    Science.gov (United States)

    Zhang, Yunhai; Loreau, Michel; He, Nianpeng; Zhang, Guangming; Han, Xingguo

    2017-08-04

    1. Global reactive nitrogen (N) is projected to further increase in the coming years. Previous studies have demonstrated that N enrichment weakens the temporal stability of the ecosystem and the primary productivity through decreased biodiversity and species asynchrony. Mowing is a globally common practise in grasslands; and infrequent mowing can maintain or increase plant diversity under N enrichment conditions. However, it is unclear how infrequent mowing affects ecosystem stability in the face of N enrichment. 2. By independently manipulating the frequency (twice vs. monthly additions per year) and rate (i.e. 0, 1, 2, 3, 5, 10, 15, 20, and 50 g N m -2 year -1 ) of NH 4 NO 3 inputs and mowing (unmown vs. mown) over 3 years (2011-2013) in a temperate grassland of northern China, we aimed to examine the interactive effects of N enrichment and mowing on ecosystem stability. 3. The results show that mowing maintained a positive relationship between species richness and ecosystem stability despite N addition, but that it exacerbated the negative effects of N addition on ecosystem stability. Mowing increased mean primary productivity and plant species richness, but it also increased the synchrony of population fluctuations and the variability of primary productivity under N enrichment, thereby contributing to a decline in the ecosystem stability. 4. Thus, our study reveals that infrequent mowing can buffer the negative effects of N enrichment on biodiversity to some extent and further increase the primary productivity, but it exacerbates the loss of ecosystem stability with N enrichment, thereby threatening local and/or semiarid regional food security.

  1. Pebble bed modular reactor fuel enrichment discrimination using delayed neutrons - HTR2008-58133

    International Nuclear Information System (INIS)

    Skoda, R.; Rataj, J.; Uhera, J.

    2008-01-01

    The Pebble Bed Modular Reactor (PBMR) is a helium-cooled, graphite-moderated high temperature nuclear power reactor which utilise fuel in form of spheres that are randomly loaded and continuously circulated through the core until they reach their prescribed end-of-life burn-up limit. When the reactor is started up for the first time, the lower-enriched start-up fuel is used, mixed with graphite spheres, to bring the core to criticality. As the core criticality is established and the start-up fuel is burned-in, the graphite spheres are progressively removed and replaced with more start-up fuel. Once it becomes necessary for maintaining power output, the higher enriched equilibrium fuel is introduced to the reactor and the start-up fuel is removed. During the initial run of the reactor it is important to discriminate between the irradiated startup fuel and the irradiated equilibrium fuel to ensure that only the equilibrium fuel is returned to the reactor. There is therefore a need for an on-line enrichment discrimination device that can discriminate between irradiated start-up fuel spheres and irradiated equilibrium fuel spheres. The device must also not be confused by the presence of any remaining graphite spheres. Due to it's on-line nature the device must accomplish the discrimination within tight time limits. Theoretical calculations and experiments show that Fuel Enrichment Discrimination based on delayed neutrons detection is possible. The paper presents calculations and experiments showing viability of the method. (authors)

  2. Process for recovering water enriched with deuterium

    International Nuclear Information System (INIS)

    Mandel, H.

    1975-01-01

    By the process proposed herewith, enrichment of deuterium in water by cooling water recirculation through series-connection of several cooling ciruits in the form of columns is obtained. With this method, conventional, open-type cooling towers without special installations can be applied, which is an important advantage as compared with a formerly proposed single-stage process with specially designed, complicated cooling towers. Series-connection of the cooling towers is carried out in such a way that the circulating water of a certain cooling circuit, which has a corresponding output value of deuterium enrichment, is conveyed to a succeeding circuit where further enrichment is achieved. The water enriched with deuterium is removed from the last cooling circuit of the series while an amount of fresch water equivalent to the water removed or evaporated altogether is fed to the first circuit of the series. (RB) [de

  3. EXTERNAL PHOTOEVAPORATION OF THE SOLAR NEBULA: JUPITER's NOBLE GAS ENRICHMENTS

    International Nuclear Information System (INIS)

    Monga, Nikhil; Desch, Steven

    2015-01-01

    We present a model explaining the elemental enrichments in Jupiter's atmosphere, particularly the noble gases Ar, Kr, and Xe. While He, Ne, and O are depleted, seven other elements show similar enrichments (∼3 times solar, relative to H). Being volatile, Ar is difficult to fractionate from H 2 . We argue that external photoevaporation by far-ultraviolet (FUV) radiation from nearby massive stars removed H 2 , He, and Ne from the solar nebula, but Ar and other species were retained because photoevaporation occurred at large heliocentric distances where temperatures were cold enough (≲ 30 K) to trap them in amorphous water ice. As the solar nebula lost H, it became relatively and uniformly enriched in other species. Our model improves on the similar model of Guillot and Hueso. We recognize that cold temperatures alone do not trap volatiles; continuous water vapor production is also necessary. We demonstrate that FUV fluxes that photoevaporated the disk generated sufficient water vapor in regions ≲ 30 K to trap gas-phase species in amorphous water ice in solar proportions. We find more efficient chemical fractionation in the outer disk: whereas the model of Guillot and Hueso predicts a factor of three enrichment when only <2% of the disk mass remains, we find the same enrichments when 30% of the disk mass remains. Finally, we predict the presence of ∼0.1 M ⊕ of water vapor in the outer solar nebula and protoplanetary disks in H II regions

  4. Enrichment and identification of polycyclic aromatic compound-degrading bacteria enriched from sediment samples.

    Science.gov (United States)

    Long, Rachel M; Lappin-Scott, Hilary M; Stevens, Jamie R

    2009-07-01

    The degradation of polycyclic aromatic compounds (PACs) has been widely studied. Knowledge of the degradation of PACs by microbial populations can be utilized in the remediation of contaminated sites. To isolate and identify PAC-degrading bacteria for potential use in future bioremediation programmes, we established a series of PAC enrichments under the same experimental conditions from a single sediment sample taken from a highly polluted estuarine site. Enrichment cultures were established using the pollutants: anthracene, phenanthrene and dibenzothiophene as a sole carbon source. The shift in microbial community structure on each of these carbon sources was monitored by analysis of a time series of samples from each culture using 16S rRNA polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE). Significantly, our findings demonstrate that shifts in the constituent species within each degradative community are directly attributable to enrichment with different PACs. Subsequently, we characterized the microorganisms comprising the degradative communities within each enrichment using 16S rRNA sequence data. Our findings demonstrate that the ability to degrade PACs is present in five divisions of the Proteobacteria and Actinobacteria. By determining the precise identity of the PAC-degrading bacterial species isolated from a single sediment sample, and by comparing our findings with previously published research, we demonstrate how bacteria with similar PAC degrading capabilities and 16S rRNA signatures are found in similarly polluted environments in geographically very distant locations, e.g., China, Italy, Japan and Hawaii. Such a finding suggests that geographical barriers do not limit the distribution of key PAC-degrading bacteria; this finding is in accordance with the Baas-Becking hypothesis "everything is everywhere; the environment selects" and may have significant consequences for the global distribution of PAC-degrading bacteria and

  5. Conversion of the Worcester Polytechnic Institute nuclear reactor to low enriched uranium

    International Nuclear Information System (INIS)

    Newton, T.H. Jr.

    1991-01-01

    The Training Reactor was converted to Low-Enriched Uranium (LEU) aluminide fuel in 1988 and 1989. Tests on the Highly-Enriched Uranium (HEU) core and LEU cores were performed and comparisons made. The testing consisted of critical loading, thermal neutron flux distribution, excess reactivity, regulating blade reactivity worth, and temperature coefficient of reactivity measurement. Comparisons between the LEU and HEU showed that the critical loading configurations were somewhat different with the HEU core consisting of 24 elements and the LEU core consisting of 21 1/3 elements with excess reactivities of 0.24% ΔK/K for the HEU and 0.16% for the LEU. Thermal neutron flux distributions showed similar trends in both the LEU and HEU cores. The regulating blade worth showed a larger LEU value due to thermal peaking in the blade region and temperature coefficients showed a more negative LEU value due to Doppler broadening. Low induced activity of the HEU fuel permitted shipment to the Westinghouse Savannah River Facility using DOT-6M type B containers on 8 August, 1989. (orig.)

  6. 75 FR 21680 - GE-Hitachi Global Laser Enrichment LLC;

    Science.gov (United States)

    2010-04-26

    ... Global Laser Enrichment LLC; Establishment of Atomic Safety and Licensing Board Pursuant to delegation by... over the following proceeding: GE-Hitachi Global Laser Enrichment LLC (GLE Commercial Facility) This... application of GE-Hitachi Global Laser Enrichment LLC for a license to possess and use source, byproduct, and...

  7. Evaluation of different enrichment methods for pathogenic Yersinia species detection by real time PCR

    Science.gov (United States)

    2014-01-01

    Background Yersiniosis is a zoonotic disease reported worldwide. Culture and PCR based protocols are the most common used methods for detection of pathogenic Yersinia species in animal samples. PCR sensitivity could be increased by an initial enrichment step. This step is particularly useful in surveillance programs, where PCR is applied to samples from asymptomatic animals. The aim of this study was to evaluate the improvement in pathogenic Yersinia species detection using a suitable enrichment method prior to the real time PCR (rtPCR). Nine different enrichment protocols were evaluated including six different broth mediums (CASO, ITC, PSB, PBS, PBSMSB and PBSSSB). Results The analysis of variance showed significant differences in Yersinia detection by rtPCR according to the enrichment protocol used. These differences were higher for Y. pseudotuberculosis than for Y. enterocolitica. In general, samples incubated at lower temperatures yielded the highest detection rates. The best results were obtained with PBSMSB and PBS2. Application of PBSMSB protocol to free-ranging wild board samples improved the detection of Y. enterocolitica by 21.2% when compared with direct rtPCR. Y. pseudotuberculosis detection was improved by 10.6% when results obtained by direct rtPCR and by PBSMSB enrichment before rtPCR were analyzed in combination. Conclusions The data obtained in the present study indicate a difference in Yersinia detection by rtPCR related to the enrichment protocol used, being PBSMSB enrichment during 15 days at 4°C and PBS during 7 days at 4°C the most efficient. The use of direct rtPCR in combination with PBSMSB enrichment prior to rtPCR resulted in an improvement in the detection rates of pathogenic Yersinia in wild boar and could be useful for application in other animal samples. PMID:25168886

  8. Uranium enrichment. 1980 annual report

    International Nuclear Information System (INIS)

    1981-05-01

    This report contains data and related information on the production of enriched uranium at the gaseous diffusion plants and an update on the construction and project control center for the gas centrifuge plant. Power usage at the gaseous diffusion plants is illustrated. The report contains several glossy color pictures of the plants and processes described. In addition to gaseous diffusion and the centrifuge process, three advanced isotope separation process are now being developed. The business operation of the enrichment plants is described; charts on revenue, balance sheets, and income statements are included

  9. Enrichment of reactive macerals in coal: its characterization and utilization in coke making

    Science.gov (United States)

    Nag, Debjani; Kopparthi, P.; Dash, P. S.; Saxena, V. K.; Chandra, S.

    2018-01-01

    Macerals in coal are of different types: reactive and inert. These macerals are differ in their physical and chemical properties. Column flotation method has been used to separate the reactive macerals in a non-coking coal. The enriched coal is then characterized in order to understand the changes in the coking potential by different techniques. It is then used in making of metallurgical coke by proper blending with other coals. Enriched coal enhance the properties of metallurgical coke. This shows a path of utilization of non-coking coal in metallurgical coke making.

  10. Effects of Enrichment Programs on the Academic Achievement of Gifted and Talented Students

    Directory of Open Access Journals (Sweden)

    Suhail Mahmoud AL-ZOUBI

    2014-12-01

    Full Text Available The aim of the study was to explore the effect of enrichment programs on the academic achievement of gifted and talented students. The sample of the study consisted of (30 gifted and talented students studying at Al-Kourah Pioneer Center for gifted and talented students (APCGTS, Jordan. An achievement test was developed and applied on the sample of the study as a pretest and posttest. The results showed the effects of enrichment programs at APCGTS on improving the academic achievement of gifted and talented students.

  11. Analysis of microbial community and nitrogen transition with enriched nitrifying soil microbes for organic hydroponics.

    Science.gov (United States)

    Saijai, Sakuntala; Ando, Akinori; Inukai, Ryuya; Shinohara, Makoto; Ogawa, Jun

    2016-06-27

    Nitrifying microbial consortia were enriched from bark compost in a water system by regulating the amounts of organic nitrogen compounds and by controlling the aeration conditions with addition of CaCO 3 for maintaining suitable pH. Repeated enrichment showed reproducible mineralization of organic nitrogen via the conversion of ammonium ions ([Formula: see text]) and nitrite ions ([Formula: see text]) into nitrate ions ([Formula: see text]). The change in microbial composition during the enrichment was investigated by PCR-DGGE analysis with a focus on prokaryote, ammonia-oxidizing bacteria, nitrite-oxidizing bacteria, and eukaryote cell types. The microbial transition had a simple profile and showed clear relation to nitrogen ions transition. Nitrosomonas and Nitrobacter were mainly detected during [Formula: see text] and [Formula: see text] oxidation, respectively. These results revealing representative microorganisms acting in each ammonification and nitrification stages will be valuable for the development of artificial simple microbial consortia for organic hydroponics that consisted of identified heterotrophs and autotrophic nitrifying bacteria.

  12. Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain.

    Directory of Open Access Journals (Sweden)

    Nicole C Riddle

    2012-09-01

    Full Text Available Chromatin environments differ greatly within a eukaryotic genome, depending on expression state, chromosomal location, and nuclear position. In genomic regions characterized by high repeat content and high gene density, chromatin structure must silence transposable elements but permit expression of embedded genes. We have investigated one such region, chromosome 4 of Drosophila melanogaster. Using chromatin-immunoprecipitation followed by microarray (ChIP-chip analysis, we examined enrichment patterns of 20 histone modifications and 25 chromosomal proteins in S2 and BG3 cells, as well as the changes in several marks resulting from mutations in key proteins. Active genes on chromosome 4 are distinct from those in euchromatin or pericentric heterochromatin: while there is a depletion of silencing marks at the transcription start sites (TSSs, HP1a and H3K9me3, but not H3K9me2, are enriched strongly over gene bodies. Intriguingly, genes on chromosome 4 are less frequently associated with paused polymerase. However, when the chromatin is altered by depleting HP1a or POF, the RNA pol II enrichment patterns of many chromosome 4 genes shift, showing a significant decrease over gene bodies but not at TSSs, accompanied by lower expression of those genes. Chromosome 4 genes have a low incidence of TRL/GAGA factor binding sites and a low T(m downstream of the TSS, characteristics that could contribute to a low incidence of RNA polymerase pausing. Our data also indicate that EGG and POF jointly regulate H3K9 methylation and promote HP1a binding over gene bodies, while HP1a targeting and H3K9 methylation are maintained at the repeats by an independent mechanism. The HP1a-enriched, POF-associated chromatin structure over the gene bodies may represent one type of adaptation for genes embedded in repetitive DNA.

  13. A strong comeback

    International Nuclear Information System (INIS)

    Marier, D.

    1992-01-01

    This article presents the results of a financial rankings survey which show a strong economic activity in the independent energy industry. The topics of the article include advisor turnover, overseas banks, and the increase in public offerings. The article identifies the top project finance investors for new projects and restructurings and rankings for lenders

  14. Device and method to enrich and process heavy water

    International Nuclear Information System (INIS)

    Hammerli, M.M.; Butler, J.P.

    1979-01-01

    A device to process and enrich heavy water is proposed which is based on a combined electrolysis catalyst exchange system in which a D 2 O enrichment of more than 99.8% is achieved in the end stage. Water partly enriched with D 2 -containing hydrogen gas from an electrolysis cell is brought into contact in a catalyst column. The water is further enriched here with deuterium. It is then fed to the electrolysis cell. Details of the apparatus are closely described. (UWI) [de

  15. Does Environmental Enrichment Reduce Stress? An Integrated Measure of Corticosterone from Feathers Provides a Novel Perspective

    Science.gov (United States)

    Fairhurst, Graham D.; Frey, Matthew D.; Reichert, James F.; Szelest, Izabela; Kelly, Debbie M.; Bortolotti, Gary R.

    2011-01-01

    Enrichment is widely used as tool for managing fearfulness, undesirable behaviors, and stress in captive animals, and for studying exploration and personality. Inconsistencies in previous studies of physiological and behavioral responses to enrichment led us to hypothesize that enrichment and its removal are stressful environmental changes to which the hormone corticosterone and fearfulness, activity, and exploration behaviors ought to be sensitive. We conducted two experiments with a captive population of wild-caught Clark's nutcrackers (Nucifraga columbiana) to assess responses to short- (10-d) and long-term (3-mo) enrichment, their removal, and the influence of novelty, within the same animal. Variation in an integrated measure of corticosterone from feathers, combined with video recordings of behaviors, suggests that how individuals perceive enrichment and its removal depends on the duration of exposure. Short- and long-term enrichment elicited different physiological responses, with the former acting as a stressor and birds exhibiting acclimation to the latter. Non-novel enrichment evoked the strongest corticosterone responses of all the treatments, suggesting that the second exposure to the same objects acted as a physiological cue, and that acclimation was overridden by negative past experience. Birds showed weak behavioral responses that were not related to corticosterone. By demonstrating that an integrated measure of glucocorticoid physiology varies significantly with changes to enrichment in the absence of agonistic interactions, our study sheds light on potential mechanisms driving physiological and behavioral responses to environmental change. PMID:21412426

  16. Environmental enrichment of brown capuchins (Cebus apella): behavioral and plasma and fecal cortisol measures of effectiveness.

    Science.gov (United States)

    Boinski, S; Swing, S P; Gross, T S; Davis, J K

    1999-01-01

    was significantly predicted by the proportions of both normal and abnormal behaviors; as the proportion of normal behaviors increased, the plasma cortisol measures decreased. Plasma cortisol weekly group means were also significantly and positively predicted by fecal cortisol weekly group means, but no behavioral measure significantly predicted fecal cortisol weekly group means. In sum, these findings argue strongly that access to a variety of toy and foraging enrichment positively affects behavioral and physiological responses to stress and enhances psychological well-being in singly housed brown capuchins.

  17. Environmental enrichment of brown capuchins (Cebus apella): Behavioral and plasma and fecal cortisol measures of effectiveness

    Science.gov (United States)

    Boinski, S.; Swing, S.P.; Gross, T.S.; Davis, J.K.

    1999-01-01

    cortisol was significantly predicted by the proportions of both normal and abnormal behaviors; as the proportion of normal behaviors increased, the plasma cortisol measures decreased. Plasma cortisol weekly group means were also significantly and positively predicted by fecal cortisol weekly group means, but no behavioral measure significantly predicted fecal cortisol weekly group means. In sum, these findings argue strongly that access to a variety of toy and foraging enrichment positively affects behavioral and physiological responses to stress and enhances psychological well-being in singly housed brown capuchins.

  18. Enrichment of tumor cells for cell kinetic analysis in human tumor biopsies using cytokeratin gating

    International Nuclear Information System (INIS)

    Haustermans, K.; Hofland, I.; Ramaekers, M.; Ivanyi, D.; Balm, A.J.M.; Geboes, K.; Lerut, T.; Schueren, E. van der; Begg, A.C.

    1996-01-01

    Purpose: To determine the feasibility of using cytokeratin antibodies to distinguish normal and malignant cells in human tumors using flow cytometry. The goal was ultimately to increase the accuracy of cell kinetic measurements on human tumor biopsies. Material and methods: A panel of four antibodies was screened on a series of 48 tumors from two centres; 22 head and neck tumors (Amsterdam) and 26 esophagus carcinomas (Leuven). First, screening was carried out by immunohistochemistry on frozen sections to test intensity of staining and the fraction of cytokeratin-positive tumor cells. The antibody showing the most positive staining was then used for flow cytometry on the same tumor. Results: The two broadest spectrum antibodies (AE1/AE3, E3/C4) showed overall the best results with immunohistochemical staining, being positive in over 95% of tumors. Good cell suspensions for DNA flow cytometry could be made from frozen material by a mechanical method, whereas enzymatic methods with trypsin or collagenase were judged failures in almost all cases. >From fresh material, both collagenase and trypsin produced good suspensions for flow cytometry, although the fraction of tumor cells, judged by proportion aneuploid cells, was markedly higher for trypsin. Using the best cytokeratin antibody for each tumor, two parameter flow cytometry was done (cytokeratin versus DNA content). Enrichment of tumor cells was then tested by measuring the fraction of aneuploid cells (the presumed malignant population) of cytokeratin-positive cells versus all cells. An enrichment factor ranging between 0 (no enrichment) and 1 (perfect enrichment, tumor cells only) was then calculated. The average enrichment was 0.60 for head and neck tumors and 0.59 for esophagus tumors. Conclusions: We conclude that this method can substantially enrich the proportion of tumor cells in biopsies from carcinomas. Application of this method could significantly enhance accuracy of tumor cell kinetic measurements

  19. Motif enrichment tool.

    Science.gov (United States)

    Blatti, Charles; Sinha, Saurabh

    2014-07-01

    The Motif Enrichment Tool (MET) provides an online interface that enables users to find major transcriptional regulators of their gene sets of interest. MET searches the appropriate regulatory region around each gene and identifies which transcription factor DNA-binding specificities (motifs) are statistically overrepresented. Motif enrichment analysis is currently available for many metazoan species including human, mouse, fruit fly, planaria and flowering plants. MET also leverages high-throughput experimental data such as ChIP-seq and DNase-seq from ENCODE and ModENCODE to identify the regulatory targets of a transcription factor with greater precision. The results from MET are produced in real time and are linked to a genome browser for easy follow-up analysis. Use of the web tool is free and open to all, and there is no login requirement. ADDRESS: http://veda.cs.uiuc.edu/MET/. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  20. The case for enrichment of uranium in Australia

    International Nuclear Information System (INIS)

    George, D.W.

    1981-01-01

    Information is presented on the number of nuclear power plants in operation and under construction and on the extent of the use of uranium. The case for enrichment of uranium in Australia is then considered in detail and the status of feasbility studies being carried out is discussed. Arguments to support an enrichment industry include: the need for additional enrichment capacity; added value; potential profitability; increased employment and industrial opportunities; and retention of depleted uranium

  1. Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus.

    Science.gov (United States)

    Hult, Caitlin; Adalsteinsson, David; Vasquez, Paula A; Lawrimore, Josh; Bennett, Maggie; York, Alyssa; Cook, Diana; Yeh, Elaine; Forest, Mark Gregory; Bloom, Kerry

    2017-11-02

    Regions of highly repetitive DNA, such as those found in the nucleolus, show a self-organization that is marked by spatial segregation and frequent self-interaction. The mechanisms that underlie the sequestration of these sub-domains are largely unknown. Using a stochastic, bead-spring representation of chromatin in budding yeast, we find enrichment of protein-mediated, dynamic chromosomal cross-links recapitulates the segregation, morphology and self-interaction of the nucleolus. Rates and enrichment of dynamic crosslinking have profound consequences on domain morphology. Our model demonstrates the nucleolus is phase separated from other chromatin in the nucleus and predicts that multiple rDNA loci will form a single nucleolus independent of their location within the genome. Fluorescent labeling of budding yeast nucleoli with CDC14-GFP revealed that a split rDNA locus indeed forms a single nucleolus. We propose that nuclear sub-domains, such as the nucleolus, result from phase separations within the nucleus, which are driven by the enrichment of protein-mediated, dynamic chromosomal crosslinks. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  2. Optimal pin enrichment distributions in nuclear reactor fuel bundles

    International Nuclear Information System (INIS)

    Lim, E.Y.

    1976-01-01

    A methodology has been developed to determine the fuel pin enrichment distribution that yields the best approximation to a prescribed power distribution in nuclear reactor fuel bundles. The problem is formulated as an optimization problem in which the optimal pin enrichments minimize the sum of squared deviations between the actual and prescribed fuel pin powers. A constant average enrichment constraint is imposed to ensure that a suitable value of reactivity is present in the bundle. When constraints are added that limit the fuel pins to a few enrichment types, one must determine not only the optimal values of the enrichment types but also the optimal distribution of the enrichment types amongst the pins. A matrix of boolean variables is used to describe the assignment of enrichment types to the pins. This nonlinear mixed integer programming problem may be rigorously solved with either exhaustive enumeration or branch and bound methods using a modification of the algorithm from the continuous problem as a suboptimization. Unfortunately these methods are extremely cumbersome and computationally overwhelming. Solutions which require only a moderate computational effort are obtained by assuming that the fuel pin enrichments in this problem are ordered as in the solution to the continuous problem. Under this assumption search schemes using either exhaustive enumeration or branch and bound become computationally attractive. An adaptation of the Hooke--Jeeves pattern search technique is shown to be especially efficient

  3. Functional properties of pasta enriched with variable cereal brans.

    Science.gov (United States)

    Kaur, Gurkirat; Sharma, Savita; Nagi, H P S; Dar, Basharat N

    2012-08-01

    To explore the potentiality of cereal brans for preparation of fiber enriched pasta, various cereal brans (Wheat, Rice, Barley and Oat) were added at 0, 5, 10, 15, 20 and 25 per cent to durum wheat semolina. The effect of cereal bran enrichment on the colour, cooking, sensory quality and shelf life of enriched pasta was assessed at ambient temperature. Pasta prepared with added fiber at 25 per cent level had the highest protein and dietary fiber content as compared to control. Enrichment with variable fiber sources improved the brightness of pasta, as colour of pasta enhanced significantly. Addition of cereal brans resulted an increase in the water absorption and cooking losses of pasta. This effect was dependent on the level and type of cereal brans. Significant correlation (r = 0.80) was obtained between water absorption and volume expansion in all types of bran enriched pasta. At 25 per cent level of supplementation, maximum solids were leached into cooking water. Bran enriched pasta required less cooking time for complete gelatinization of starch. Increasing level of cereal brans had significantly affected the overall acceptability of enriched pasta. Cooking quality of pasta remained constant during storage. Non significant effect of storage was found on water activity, free fatty acids. Enriched pasta (15 per cent level of wheat, rice and oat bran and 10 per cent barley bran) was highly acceptable upto 4 months of storage with respect to quality.

  4. Effect of oxygen enrichment in air on acid gas combustion under Claus conditions

    KAUST Repository

    Ibrahim, Salisu

    2013-09-01

    Results are presented to examine the combustion of acid gas (H2S and CO2) in hydrogen-fueled flames using a mixture of oxygen and nitrogen under Claus conditions (Φ = 3). Specifically the effect of oxygen enrichment in the above flames is examined. The compositions of acid gas examined are100% H2S and 50% H2S/50% CO2 with different percentages of oxygen enrichment (0%, 19.3% and 69.3%) in the oxygen/nitrogen mixtures. The results revealed that combustion of acid gas formed SO2 wherein the mole fraction of SO2 increased to an asymptotic value at all the oxygen concentrations examined. In addition, increase in oxygen enrichment of the air resulted in increased amounts of SO2 rather than the formation of more desirable elemental sulfur. In case of 50% H2S/50% CO2 acid gas, carbon monoxide mole fraction increased with oxygen enrichment which is an indicator to the availability of additional amounts of oxygen into the reaction pool. This gas mixture resulted in the formation of other sulfurous–carbonaceous compounds (COS and CS2) due to the presence of carbon monoxide. The results showed that the rate of COS formation increased with oxygen enrichment due to the availability of higher amounts of CO while that of CS2 reduced. The global reactions responsible for this observed phenomenon are presented.

  5. Synthesis of fertilizers nitrogen and 15N-enriched. Pt. I. Production of enriched 15N-anhydrous ammonia

    International Nuclear Information System (INIS)

    Bendassolli, J.A.; Mortatti, J.; Trivelin, P.C.O.; Victoria, R.L.

    1988-01-01

    The results of 15 N-anhydrous ammonia production through reaction between 15 N-enriched ammonium sulphate and sodium hidroxide are reported. Influence of the reaction temperature, carrier gas flow, reaction time and mass of ammonium sulphate on the production of anhydrous ammonia were studied. Analyses for the cost of production of 5% atoms in 15 N-enriched anhydrous ammonia were made. (M.A.C.) [pt

  6. Some Main Results of Commissioning of the Dalat Research Reactor with Low Enriched Fuel

    International Nuclear Information System (INIS)

    Nguyen Nhi Dien; Luong Ba Vien; Pham Van Lam; Le Vinh Vinh; Huynh Ton Nghiem

    2014-01-01

    After completion of design calculation of the Dalat Nuclear Research Reactor (DNRR) for conversion from high-enriched uranium fuel (HEU) to low-enriched uranium (LEU) fuel, the commissioning programme for DNRR with entire core loaded with LEU fuel was successfully carried out from 24 November 2011 to 13 January 2012. The experimental results obtained during the implementation of commissioning programme showed a good agreement with design calculations and affirmed that the DNRR with LEU core have met all safety and exploiting requirements. (author)

  7. 235U enrichment determination on UF6 cylinders with CZT detectors

    Science.gov (United States)

    Berndt, Reinhard; Mortreau, Patricia

    2018-04-01

    Measurements of uranium enrichment in UF6 transit cylinders are an important nuclear safeguards verification task, which is performed using a non-destructive assay method, the traditional enrichment meter, which involves measuring the count rate of the 186 keV gamma ray. This provides a direct measure of the 235U enrichment. Measurements are typically performed using either high-resolution detectors (Germanium) with e-cooling and battery operation, or portable devices equipped with low resolution detectors (NaI). Despite good results being achieved when measuring Low Enriched Uranium in 30B type cylinders and natural uranium in 48Y type containers using both detector systems, there are situations, which preclude the use of one or both of these systems. The focus of this work is to address some of the recognized limitations in relation to the current use of the above detector systems by considering the feasibility of an inspection instrument for 235U enrichment measurements on UF6 cylinders using the compact and light Cadmium Zinc Telluride (CZT) detectors. In the present work, test measurements were carried out, under field conditions and on full-size objects, with different CZT detectors, in particular for situations where existing systems cannot be used e.g. for stacks of 48Y type containers with depleted uranium. The main result of this study shows that the CZT detectors, actually a cluster of four μCZT1500 micro spectrometers provide as good results as the germanium detector in the ORTEC Micro-trans SPEC HPGe Portable spectrometer, and most importantly in particular for natural and depleted uranium in 48Y cylinders.

  8. Quality and nutritional properties of pasta products enriched with immature wheat grain.

    Science.gov (United States)

    Casiraghi, Maria Cristina; Pagani, Maria Ambrogina; Erba, Daniela; Marti, Alessandra; Cecchini, Cristina; D'Egidio, Maria Grazia

    2013-08-01

    In this study, nutritional and sensory properties of pasta enriched with 30% immature wheat grain (IWG), a natural source of fructo-oligosaccharides (FOS), are evaluated. Colour and cooking quality, nutritional value and glycaemic index (GI) of pasta were assessed in comparison with commercially enriched inulin and 100% wholewheat pastas. IWG integration induced deep changes in colour, without negatively affecting the cooking quality of pasta, and promoted nutritional quality by increasing the fibre content; IWG pasta presented a remarkable leaching of FOS in cooking water, thus providing only 1 g of FOS per serving. IWG pastas showed a GI of 67 (dried) and 79 (fresh), not significantly different from commercial pasta products. IWG can be considered an interesting ingredient to obtain functional products 'naturally enriched' in FOS and fibre. Results about FOS leaching suggest that, in dealing with functional effects, the actual prebiotic content should be carefully considered on food 'as eaten'.

  9. How can Korea secure uranium enrichment and spent fuel reprocessing rights?

    International Nuclear Information System (INIS)

    Roh, Seungkook; Kim, Wonjoon

    2014-01-01

    South Korea is heavily dependent on energy resources from other countries and nuclear energy accounts for 31% of Korea's electric power generation as a major energy. However, Korea has many limitations in uranium enrichment and spent fuel reprocessing under the current Korea-U.S. nuclear agreement, although they are economically and politically important to Korea due to a significant problems in nuclear fuel storages. Therefore, in this paper, we first examine those example countries – Japan, Vietnam, and Iran – that have made nuclear agreements with the U.S. or have changed their agreements to allow the enrichment of uranium and the reprocessing of spent fuel. Then, we analyze those countries' nuclear energy policies and review their strategic repositioning in the relationship with the U.S. We find that a strong political stance for peaceful usage of nuclear energy including the legislation of nuclear laws as was the case of Japan. In addition, it is important for Korea to acquire advanced technological capability such as sodium-cooled fast reactor (SFR) because SFR technologies require plutonium to be used as fuel rather than uranium-235. In addition, Korea needs to leverage its position in nuclear agreement between China and the U.S. as was the case of Vietnam

  10. Coordinated Speed Oscillations in Schooling Killifish Enrich Social Communication

    Science.gov (United States)

    Swain, Daniel T.; Couzin, Iain D.; Leonard, Naomi Ehrich

    2015-10-01

    We examine the spatial dynamics of individuals in small schools of banded killifish ( Fundulus diaphanus) that exhibit rhythmic, oscillating speed, typically with sustained, coordinated, out-of-phase speed oscillations as they move around a shallow water tank. We show that the relative motion among the fish yields a periodically time-varying network of social interactions that enriches visually driven social communication. The oscillations lead to the regular making and breaking of occlusions, which we term "switching." We show that the rate of convergence to consensus (biologically, the capacity for individuals in groups to achieve effective coordinated motion) governed by the switching outperforms static alternatives, and performs as well as the less practical case of every fish sensing every other fish. We show further that the oscillations in speed yield oscillations in relative bearing between fish over a range that includes the angles previously predicted to be optimal for a fish to detect changes in heading and speed of its neighbors. To investigate systematically, we derive and analyze a dynamic model of interacting agents that move with oscillatory speed. We show that coordinated circular motion of the school leads to systematic cycling of spatial ordering of agents and possibilities for enriched spatial density of measurements of the external environment. Our results highlight the potential benefits of dynamic communication topologies in collective animal behavior, and suggest new, useful control laws for the distributed coordination of mobile robotic networks.

  11. Acceptability and nutritional value of dark chocolate enriched with baru almonds, flaxseed and quinoa

    Directory of Open Access Journals (Sweden)

    Jullyana Borges de Freitas

    2016-04-01

    Full Text Available This study aimed to formulate dark chocolate enriched with baru almonds, flaxseed and quinoa (9% in replacement of chocolate, as well as assess the acceptability (global acceptance, appearance and purchase intent and the nutritional value of the formulations. The various chocolate samples were considered accepted and showed good levels of purchase intent, except for the variation enriched with flaxseed. The chocolate samples showed high content of fiber (27 to 40 g/100g, and lower energy value (385 to 413 kcal/100g compared to conventional dark chocolates with almonds (7 to 11 g of dietary fiber/100g and 500 to 550 kcal/100g, thus providing a healthier alternative for consumers.

  12. Principles and techniques of uranium enrichment

    International Nuclear Information System (INIS)

    Frejacques, Claude; Mezin, Michel

    1975-01-01

    The main separation processes already used industrially or likely to be used before the end of century (gas diffusion, ultracentrifugation, laser, the nozzle process, a process developed in South Africa) are presented. Some data on the costs of the enrichment are clarified. The main characteristics of the enrichment market in which the Eurodif plant is called upon, on the expiration of five years, to take a foremost place are reported [fr

  13. Enrichment of water solube substances at heat transfer surfaces in steam boilers and steam generators - a literature survey

    International Nuclear Information System (INIS)

    Kelen, T.

    1975-03-01

    A literature survey has been made to determine the possible need for investigations into enrichment at heat transport surfaces. The survey shows that enrichment in furnace tubes of carbon steel has led both to hydrogen embrittlement as a result of a reduction of pH and to local tube wall thinning and alkaline stress corrosion following an increase of pH. Damage caused by enrichment has occurred also in the steam generators of PWR's. Information concerning measured enrichment, observed hide-out, occurrence of normally easily soluble deposits as well as of corrosion damage requiring high concentrations lead to the conclusion that enrichment factors of the order of 10 000 are to be expected in some instances. The relationship between operational conditions and enrichment in specific cases is, however, poorly documented. The tendency to hide out varies for different substances. This is however not evidently equivalent to variation of the corresponding enrichment factor in the solution. Enrichment at heat transfer surfaces can arise as the result of one or several of the following effects: - formation of porous deposits - poor circulation - high densities of heat flow rate - departure from nucleate boiling leading to dry-out - steam blanketing. The conclusion reached from the literature survey is that knowledge of the degree of enrichment produced under specific operational conditions is extremely inadequate. (author)

  14. A short-term intervention trial with selenate, selenium-enriched yeast and selenium-enriched milk: effects on oxidative defence regulation

    DEFF Research Database (Denmark)

    Ravn-Haren, Gitte; Bugel, Susanne; Krath, Britta

    2008-01-01

    -enriched yeast or Se-enriched milk. We found no effect on plasma lipid resistance to oxidation, total cholesterol, TAG, HDL- and LDL-cholesterol, GPX, glutathione reductase (GR) and glutathione S-transferase (GST) activities measured in erythrocytes, GPX and GR activities determined in plasma, or GR and GST...

  15. Huanglongbing impairs the rhizosphere-to-rhizoplane enrichment process of the citrus root-associated microbiome.

    Science.gov (United States)

    Zhang, Yunzeng; Xu, Jin; Riera, Nadia; Jin, Tao; Li, Jinyun; Wang, Nian

    2017-08-10

    Roots are the primary site for plant-microbe interactions. Among the three root-associated layers (i.e., rhizosphere, rhizoplane, and endorhiza), the rhizoplane is a key component serving a critical gating role that controls microbial entry into plant roots. The microbial communities colonizing the three layers are believed to be gradually enriched from the bulk soil inoculum. However, it is unknown how this enrichment process, particularly the rhizosphere to rhizoplane step, is affected by biotic stresses, such as disease. In this study, we address this question using the citrus root-associated microbiome as a model. We identified the rhizosphere-to-rhizoplane-enriched taxonomic and functional properties of the citrus root-associated microbiome and determined how they were affected by Huanglongbing (HLB), a severe systemic disease caused by Candidatus Liberibacter asiaticus, using metagenomic and metatranscriptomic approaches. Multiple rhizoplane-enriched genera were identified, with Bradyrhizobium and Burkholderia being the most dominant. Plant-derived carbon sources are an important driving force for the enrichment process. The enrichment of functional attributes, such as motility, chemotaxis, secretion systems, and lipopolysaccharide (LPS) synthesis, demonstrated more active microbe-plant interactions on the rhizoplane than the rhizosphere. We observed that HLB impaired the rhizosphere-to-rhizoplane enrichment process of the citrus root-associated microbiome in three ways: (1) by decreasing the relative abundance of most rhizoplane-enriched genera; (2) by reducing the relative abundance and/or expression activity of the functional attributes involved in microbe-plant interactions; and (3) by recruiting more functional features involved in autotrophic life cycle adaptation, such as carbon fixation and nitrogen nitrification in the HLB rhizoplane microbiome. Finally, our data showed that inoculation of Burkholderia strains isolated from the healthy citrus root

  16. Flexible work arrangements, job satisfaction, and turnover intentions: the mediating role of work-to-family enrichment.

    Science.gov (United States)

    McNall, Laurel A; Masuda, Aline D; Nicklin, Jessica M

    2010-01-01

    The authors examined the relation between the availability of 2 popular types of flexible work arrangements (i.e., flextime and compressed workweek) and work-to-family enrichment and, in turn, the relation between work-to-family enrichment and (a) job satisfaction and (b) turnover intentions. In a sample of 220 employed working adults, hierarchical regression analyses showed that work-to-family enrichment mediated the relation between flexible work arrangements and both job satisfaction and turnover intentions, even after controlling for gender, age, marital status, education, number of children, and hours worked. Thus, the availability of flexible work arrangements such as flextime and compressed workweek seems to help employees experience greater enrichment from work to home, which, in turn, is associated with higher job satisfaction and lower turnover intentions. The authors discuss the implications for research and practice.

  17. The Passive Neutron Enrichment Meter for Uranium Cylinder Assay

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Karen A.; Menlove, Howard O.; Swinhoe, Martyn T.; Marlow, Johanna B. [Safeguards Science and Technology Group (N-1), Los Alamos National Laboratory, Los Alamos (United States)

    2011-12-15

    As fuel cycle technology becomes more prevalent around the world, international safeguards have become increasingly important in verifying that nuclear materials have not been diverted. Uranium enrichment technology is a critical pathway to nuclear weapons development, making safeguards of enrichment facilities especially important. Independently-verifiable material accountancy is a fundamental measure in detecting diversion of nuclear materials. This paper is about a new instrument for uranium cylinder assay for enrichment plant safeguards called the Passive Neutron Enrichment Meter (PNEM). The measurement objective is to simultaneously verify uranium mass and enrichment in Uf6 cylinders. It can be used with feed, product, and tails cylinders. Here, we consider the enrichment range up to 5% {sup 235}U. The concept is to use the Doubles-to-Singles count rate to give a measure of the {sup 235}U enrichment and the Singles count rate to provide a measure of the total uranium mass. The cadmium ratio is an additional signature for the enrichment that is especially useful for feed and tails cylinders. PNEM is a {sup 3}He-based system that consists of two portable detector pods. Uranium enrichment in UF{sub 6} cylinders is typically determined using a gamma-ray-based method that only samples a tiny volume of the cylinder's content and requires knowledge of the cylinder wall thickness. The PNEM approach has several advantages over gamma-ray-based methods including a deeper penetration depth into the cylinder, meaning it can be used with heterogeneous isotopic mixtures of UF{sub 6}. In this paper, we describe a Monte Carlo modelling study where we have examined the sensitivity of the system to systematic uncertainties such as the distribution of UF{sub 6} within the cylinder. We also compare characterization measurements of the PNEM prototype to the expected measurements calculated with Monte Carlo simulations.

  18. Novel meat-enriched foods for older consumers.

    Science.gov (United States)

    Farouk, Mustafa M; Yoo, Michelle J Y; Hamid, Nazimah S A; Staincliffe, Maryann; Davies, Briar; Knowles, Scott O

    2018-02-01

    Red meat enriched versions of bread, spaghetti, yoghurt, ice cream and chocolate were prototyped and assessed for some of their physical, chemical and microbiological properties, as well as sensory appeal. The protein content of the products were significantly increased and their colour went darker with meat enrichment (pice cream meltability and yoghurt apparent viscosity decreased with meat enrichment (pice cream and spaghetti were not affected (p>0.05) but that of non-flavoured ice cream and yoghurt went down (pindustry stretch its established business models, and encouraging further development of novel food choices for elderly and other groups of consumers. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. WaveSeq: a novel data-driven method of detecting histone modification enrichments using wavelets.

    Directory of Open Access Journals (Sweden)

    Apratim Mitra

    Full Text Available BACKGROUND: Chromatin immunoprecipitation followed by next-generation sequencing is a genome-wide analysis technique that can be used to detect various epigenetic phenomena such as, transcription factor binding sites and histone modifications. Histone modification profiles can be either punctate or diffuse which makes it difficult to distinguish regions of enrichment from background noise. With the discovery of histone marks having a wide variety of enrichment patterns, there is an urgent need for analysis methods that are robust to various data characteristics and capable of detecting a broad range of enrichment patterns. RESULTS: To address these challenges we propose WaveSeq, a novel data-driven method of detecting regions of significant enrichment in ChIP-Seq data. Our approach utilizes the wavelet transform, is free of distributional assumptions and is robust to diverse data characteristics such as low signal-to-noise ratios and broad enrichment patterns. Using publicly available datasets we showed that WaveSeq compares favorably with other published methods, exhibiting high sensitivity and precision for both punctate and diffuse enrichment regions even in the absence of a control data set. The application of our algorithm to a complex histone modification data set helped make novel functional discoveries which further underlined its utility in such an experimental setup. CONCLUSIONS: WaveSeq is a highly sensitive method capable of accurate identification of enriched regions in a broad range of data sets. WaveSeq can detect both narrow and broad peaks with a high degree of accuracy even in low signal-to-noise ratio data sets. WaveSeq is also suited for application in complex experimental scenarios, helping make biologically relevant functional discoveries.

  20. A diet enriched with Mugil cephalus processed roes modulates the tissue lipid profile in healthy rats: a biochemical and chemometric assessment.

    Science.gov (United States)

    Rosa, A; Atzeri, A; Putzu, D; Scano, P

    2016-01-01

    The effect of a diet enriched with mullet bottarga on the lipid profile (total lipids, total cholesterol, unsaturated fatty acids, α-tocopherol, and hydroperoxides) of plasma, liver, kidney, brain, and perirenal adipose tissues of healthy rats was investigated. Rats fed a 10% bottarga enriched-diet for 5 days showed body weights and tissue total lipid and cholesterol levels similar to those of animals fed control diet. Univariate and multivariate results showed that bottarga enriched-diet modified the fatty acid profile in all tissues, except brain. Significant increases of n-3 PUFA, particularly EPA, were observed together with a 20:4 n-6 decrease in plasma, liver, and kidney. Perirenal adipose tissue showed a fat accumulation that reflected the diet composition. The overall data suggest that mullet bottarga may be considered as a natural bioavailable source of n-3 PUFA and qualify it as a traditional food product with functional properties and a potential functional ingredient for preparation of n-3 PUFA enriched foods.

  1. A ChIP-Seq benchmark shows that sequence conservation mainly improves detection of strong transcription factor binding sites.

    Directory of Open Access Journals (Sweden)

    Tony Håndstad

    Full Text Available BACKGROUND: Transcription factors are important controllers of gene expression and mapping transcription factor binding sites (TFBS is key to inferring transcription factor regulatory networks. Several methods for predicting TFBS exist, but there are no standard genome-wide datasets on which to assess the performance of these prediction methods. Also, it is believed that information about sequence conservation across different genomes can generally improve accuracy of motif-based predictors, but it is not clear under what circumstances use of conservation is most beneficial. RESULTS: Here we use published ChIP-seq data and an improved peak detection method to create comprehensive benchmark datasets for prediction methods which use known descriptors or binding motifs to detect TFBS in genomic sequences. We use this benchmark to assess the performance of five different prediction methods and find that the methods that use information about sequence conservation generally perform better than simpler motif-scanning methods. The difference is greater on high-affinity peaks and when using short and information-poor motifs. However, if the motifs are specific and information-rich, we find that simple motif-scanning methods can perform better than conservation-based methods. CONCLUSIONS: Our benchmark provides a comprehensive test that can be used to rank the relative performance of transcription factor binding site prediction methods. Moreover, our results show that, contrary to previous reports, sequence conservation is better suited for predicting strong than weak transcription factor binding sites.

  2. Strong Cation Exchange Chromatography in Analysis of Posttranslational Modifications: Innovations and Perspectives

    Science.gov (United States)

    Edelmann, Mariola J.

    2011-01-01

    Strong cation exchange (SCX) chromatography has been utilized as an excellent separation technique that can be combined with reversed-phase (RP) chromatography, which is frequently used in peptide mass spectrometry. Although SCX is valuable as the second component of such two-dimensional separation methods, its application goes far beyond efficient fractionation of complex peptide mixtures. Here I describe how SCX facilitates mapping of the protein posttranslational modifications (PTMs), specifically phosphorylation and N-terminal acetylation. The SCX chromatography has been mainly used for enrichment of these two PTMs, but it might also be beneficial for high-throughput analysis of other modifications that alter the net charge of a peptide. PMID:22174558

  3. Uranium enrichment management review. Final report

    International Nuclear Information System (INIS)

    Ellett, J.D.; Rieke, W.B.; Simpson, J.W.; Sullivan, P.E.

    1980-01-01

    The uranium enrichment enterprise of the US Department of Energy (DOE) provides enriched nuclear fuel for private and government utilities domestically and abroad. The enterprise, in effect, provides a commercial service and represents a signficant business operation within the US government: more than $1 billion in revenues annually and future capital expenditures estimated at several billions of dollars. As a result, in May 1980, the Assistant Secretary for Resource Applications within DOE requested that a group of experienced business executives be assembled to review the operation, financing, and management of the uranium enrichment enterprise as a basis for advising the Secretary of Energy. The review group was specifically asked to focus on the management activities to which sound business practices could be applied. The group developed findings and recommendations in six areas: management of operations and construction; long-range planning; marketing of enrichment services; financial management; research and development; and general management. The chapters of this report present first the management review group's recommendations in the six areas evaluated and then the findings and issues in each area. An appendix provides the group's calendar of meetings. A list of major reference sources used in the course of the study is also included. 12 references

  4. Measurement of the enrichment of uranium-hexafluoride gas in product pipes in the centrifuge enrichment plant at Almelo

    International Nuclear Information System (INIS)

    Packer, T.W.; Lees, E.W.; Aaldijk, J.K.; Harry, R.J.S.

    1987-09-01

    One of the objectives of safeguarding centrifuge enrichment plants is to apply non-destructive measurements inside the cascade area to confirm that the enrichment level is in the low enriched uranium range. Research in the UK and USA has developed a NDA instrument which can confirm the presence of low enriched uranium on a rapid go/no go basis in cascade header pipework of their centrifuge enrichment plants. The instrument is based on a gamma spectroscopic measurement coupled with an X-ray fluorescence analysis. This report gives the results of measurements carried out at Almelo by the UKAEA Harwell, ECN Petten and KFA Juelich to determine if these techniques could be employed at Almelo and Gronau. The energy dispersive X-ray fluorescence analysis has been applied to determine the total mass of uranium in the gas phase, and the deposit correction technique and the two geometry technique have been applied at Almelo to correct the measured gamma intensities for those emitted by the deposit. After an executive summary the report discusses the principles of the two correction methods. A short description of the equipment precedes the presentation of the results of the measurements and the discussion. After the conclusions the report contains two appendices which contain the derivation of the formulae for the deposit correction technique and a discussion of the systematic errors of this technique. 8 figs.; 11 refs.; 6 tables

  5. Assuaging Nuclear Energy Risks: The Angarsk International Uranium Enrichment Center

    International Nuclear Information System (INIS)

    Myers, Astasia

    2011-01-01

    The recent nuclear renaissance has motivated many countries, especially developing nations, to plan and build nuclear power reactors. However, domestic low enriched uranium demands may trigger nations to construct indigenous enrichment facilities, which could be redirected to fabricate high enriched uranium for nuclear weapons. The potential advantages of establishing multinational uranium enrichment sites are numerous including increased low enrichment uranium access with decreased nuclear proliferation risks. While multinational nuclear initiatives have been discussed, Russia is the first nation to actualize this concept with their Angarsk International Uranium Enrichment Center (IUEC). This paper provides an overview of the historical and modern context of the multinational nuclear fuel cycle as well as the evolution of Russia's IUEC, which exemplifies how international fuel cycle cooperation is an alternative to domestic facilities.

  6. Effect of different enrichment strategies on microbial community structure in petroleum-contaminated marine sediment in Dalian, China.

    Science.gov (United States)

    Chen, Chao; Liu, Qiu; Liu, Changjian; Yu, Jicheng

    2017-04-15

    An oil spill occurred at Xingang Port, Dalian, China in 2010. Four years after this spill, oil contamination was still detected in samples collected nearby. In this study, the strains that evolved in the sediment were screened by high-throughput sequencing technology. Most of these strains were genera reported to have functions associated with crude oil biodegradation. The diversities and numbers of microbes were monitored through enrichment culturing; the dominant strains propagated at first, but the enrichment could not be continued, which indicated that the prolonged culture was not effective in the enrichment of the micro-consortium. Oxygen was also observed to affect the propagation of the dominant microbes. The results showed the role of culture strategies and oxygen in the enrichment of the petroleum-degrading microbes. Therefore, dominant strains could be screened by optimizing both the enrichment time and oxygen concentration used for culturing to facilitate oil biodegradation in the marine ecosystem. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Triassic regolithization: A major stage of pre-enrichment in the formation of unconformity related deposits in Southern France

    International Nuclear Information System (INIS)

    Schmitt, J.M.; Clement, J.Y.

    1989-01-01

    The formation of unconformity related uranium deposits in Canada and Australia is currently thought to have involved some stage of preconcentration within the Proterozoic regolith. Uranium deposits in the southern Massif central (France) are spatially linked to the Mesozoic unconformity. Under this unconformity, rocks of the Hercynian basement as well as Permo-Carboniferous sediments show a regolithic alteration dating back to the Late Permian to Late Triassic period. On the elevated parts of the Triassic landscape, 30 to 50 m deep weathering profiles are preserved. Three main zones can be distinguished: a lower pink coloured zone, showing partly albitized and chloritized rocks: a middle bleached zone with neogenic clays; and an upper reddish zone with Fe-Mn oxyhydroxides. Towards the Triassic basin, much deeper (200-300 m) alteration profiles are observed on Permo-Carboniferous sediments. The two upper regolithic zones are present, but the lower albitized one is very developed with two subzones: analcite/albite at the top, and K-feldspar/albite at the bottom. Geochemical data show that potassium is fixed in the uppermost horizons of the regolith, whereas sodium is transported towards the lower horizons and basin areas and fixed in analcite/albite zones. Uranium, vanadium, copper and less mobile elements such as titanium and zirconium are strongly leached from the weathering profiles in elevated parts of the landscape but are enriched in basin zones of albitization up to 5-15 times. Thus, solutions generated from the weathering profiles have brought about a major redistribution of uranium in the Triassic landscape. The remarkable applanation and tectonic stability of the area as well as a subarid climate seem to have favoured this 'regolithization' process. In southern France, geochemical differentiation during the Triassic has thus given rise to important uranium pre-enrichment, and the regolith is a major control for later uranium deposits. (author). 16 refs, 8

  8. An Enriching Community.

    Science.gov (United States)

    Holland, Nancy A.; Burroughs, Jean

    2001-01-01

    Successful school-community partnerships in Volusia (Florida) Public Schools are the results of marketing creatively, meeting community members' needs, and bringing the right people together. The 3-year old program now offers students of all ages an expanding list of enrichment classes on many subjects for a nominal fee. (MLH)

  9. Nutritional enrichment of larval fish feed with thraustochytrid producing polyunsaturated fatty acids and xanthophylls.

    Science.gov (United States)

    Yamasaki, Takashi; Aki, Tsunehiro; Mori, Yuhsuke; Yamamoto, Takeki; Shinozaki, Masami; Kawamoto, Seiji; Ono, Kazuhisa

    2007-09-01

    In marine aquaculture, rotifers and Artemia nauplii employed as larval fish feed are often nutritionally enriched with forage such as yeast and algal cells supplemented with polyunsaturated fatty acids and xanthophylls, which are required for normal growth and a high survival ratio of fish larvae. To reduce the enrichment steps, we propose here the use of a marine thraustochytrid strain, Schizochytrium sp. KH105, producing docosahexaenoic acid, docosapentaenoic acid, canthaxanthin, and astaxanthin. The KH105 cells prepared by cultivation under optimized conditions were successfully incorporated by rotifers and Artemia nauplii. The contents of docosahexaenoic acid surpassed the levels required in feed for fish larvae, and the enriched Artemia showed an increased body length. The results demonstrate that we have developed an improved method of increasing the dietary value of larval fish feed.

  10. Fluorine nuclear magnetic resonance study of enrichment effects in gaseous, liquid and solid uranium hexafluoride

    International Nuclear Information System (INIS)

    Ursu, I.; Demco, D.E.; Simplaceanu, V.; Valcu, N.

    1977-01-01

    The nuclear magnetic resonance method is able to provide information concerning the isotopic content of 235 U in UF 6 by means of measuring the nuclear magnetic transverse relaxation time (T,L2) of 19 F nuclei in liquid UF 6 . In this work, the sources of errors in the T 2 measurements have been analysed and methods for reducing them are dicussed. Typical errors in T 2 determinations are below 2%. The enrichment estimations made by using the linear calibration curves had a deviation of less than 2% with some exceptions. It was found that the chemical impurities may significantly affect the enrichment estimations. 19 F NMR spectra of liquid and gaseous UF 6 at low pressures did not reveal any structure or enrichment effect. The longitudinal nuclear magnetic relaxation of 19 F nuclei in low pressure, gaseous and solid UF 6 showed no enrichment dependence, nor the dipolar relaxation time in solid UF 6 did. (author)

  11. Is there a potential win for companies when women enrich their role of workers through the enrichement of their family lives?

    OpenAIRE

    Oliveira, Inês Martins

    2015-01-01

    While the work-family relation conflict literature has received much attention, there is a lack of empirical evidence towards work-family positive relation. Furthermore, there is a lack of understanding and recognition of possible benefits obtained by skills’ development during maternity. This study concludes that a family-work relation has a positive outcome, namely the enrichment. It was evident that there is a potential win when women enrich their role as workers through the enrichment of ...

  12. Narcissus tazetta lectin shows strong inhibitory effects against ...

    Indian Academy of Sciences (India)

    Prakash

    against human enveloped viruses (Balzarini 2007a). They ... NTL with a high selective index (SI=CC50/IC50 >141) resulting from its potent antiviral activity and low cytotoxicity demonstrates a potential for biotechnological development as an ...

  13. Dimethylated H3K27 Is a Repressive Epigenetic Histone Mark in the Protist Entamoeba histolytica and Is Significantly Enriched in Genes Silenced via the RNAi Pathway*

    Science.gov (United States)

    Foda, Bardees M.; Singh, Upinder

    2015-01-01

    RNA interference (RNAi) is a fundamental biological process that plays a crucial role in regulation of gene expression in many organisms. Transcriptional gene silencing (TGS) is one of the important nuclear roles of RNAi. Our previous data show that Entamoeba histolytica has a robust RNAi pathway that links to TGS via Argonaute 2-2 (Ago2-2) associated 27-nucleotide small RNAs with 5′-polyphosphate termini. Here, we report the first repressive histone mark to be identified in E. histolytica, dimethylation of H3K27 (H3K27Me2), and demonstrate that it is enriched at genes that are silenced by RNAi-mediated TGS. An RNAi-silencing trigger can induce H3K27Me2 deposits at both episomal and chromosomal loci, mediating gene silencing. Our data support two phases of RNAi-mediated TGS: an active silencing phase where the RNAi trigger is present and both H3K27Me2 and Ago2-2 concurrently enrich at chromosomal loci; and an established silencing phase in which the RNAi trigger is removed, but gene silencing with H3K27Me2 enrichment persist independently of Ago2-2 deposition. Importantly, some genes display resistance to chromosomal silencing despite induction of functional small RNAs. In those situations, the RNAi-triggering plasmid that is maintained episomally gets partially silenced and has H3K27Me2 enrichment, but the chromosomal copy displays no repressive histone enrichment. Our data are consistent with a model in which H3K27Me2 is a repressive histone modification, which is strongly associated with transcriptional repression. This is the first example of an epigenetic histone modification that functions to mediate RNAi-mediated TGS in the deep-branching eukaryote E. histolytica. PMID:26149683

  14. Dimethylated H3K27 Is a Repressive Epigenetic Histone Mark in the Protist Entamoeba histolytica and Is Significantly Enriched in Genes Silenced via the RNAi Pathway.

    Science.gov (United States)

    Foda, Bardees M; Singh, Upinder

    2015-08-21

    RNA interference (RNAi) is a fundamental biological process that plays a crucial role in regulation of gene expression in many organisms. Transcriptional gene silencing (TGS) is one of the important nuclear roles of RNAi. Our previous data show that Entamoeba histolytica has a robust RNAi pathway that links to TGS via Argonaute 2-2 (Ago2-2) associated 27-nucleotide small RNAs with 5'-polyphosphate termini. Here, we report the first repressive histone mark to be identified in E. histolytica, dimethylation of H3K27 (H3K27Me2), and demonstrate that it is enriched at genes that are silenced by RNAi-mediated TGS. An RNAi-silencing trigger can induce H3K27Me2 deposits at both episomal and chromosomal loci, mediating gene silencing. Our data support two phases of RNAi-mediated TGS: an active silencing phase where the RNAi trigger is present and both H3K27Me2 and Ago2-2 concurrently enrich at chromosomal loci; and an established silencing phase in which the RNAi trigger is removed, but gene silencing with H3K27Me2 enrichment persist independently of Ago2-2 deposition. Importantly, some genes display resistance to chromosomal silencing despite induction of functional small RNAs. In those situations, the RNAi-triggering plasmid that is maintained episomally gets partially silenced and has H3K27Me2 enrichment, but the chromosomal copy displays no repressive histone enrichment. Our data are consistent with a model in which H3K27Me2 is a repressive histone modification, which is strongly associated with transcriptional repression. This is the first example of an epigenetic histone modification that functions to mediate RNAi-mediated TGS in the deep-branching eukaryote E. histolytica. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  15. Environmental Enrichment for Broiler Breeders: An Undeveloped Field

    DEFF Research Database (Denmark)

    Riber, Anja Brinch; Jong, Ingrid de; van de Werd, Heleen A.

    2017-01-01

    Welfare problems, such as hunger, frustration, aggression, and abnormal sexual behavior, are commonly found in broiler breeder production. To prevent or reduce these welfare problems, it has been suggested to provide stimulating enriched environments. We review the effect of the different types...... of environmental enrichment for broiler breeders, which have been described in the scientific literature, on behavior and welfare. Environmental enrichment is defined as an improvement of the environment of captive animals, which increases the behavioral opportunities of the animal and leads to improvements...... in biological function. This definition has been broadened to include practical and economic aspects as any enrichment strategy that adversely affects the health of animals (e.g., environmental hygiene), or that has too many economic or practical constraints will never be implemented on commercial farms...

  16. The uranium enrichment industry and the SILEX process

    International Nuclear Information System (INIS)

    Goldsworthy, M.

    1999-01-01

    Silex Systems Limited has been developing a new laser isotope separation process since 1992. The principle application of the SILEX Technology is Uranium Enrichment, the key step in the production of fuel for nuclear power plants. The Uranium Enrichment industry, today worth ∼ US$3.5 Billion p.a., is dominated by four major players, the largest being USEC with almost 40% of the market. In 1996, an agreement was signed between Silex and USEC to develop SILEX Technology for potential application to Uranium Enrichment. The SILEX process is a low cost, energy efficient scheme which may provide significant commercial advantage over current technology and competing laser processes. Silex is also investigating possible application to the enrichment of Silicon, Carbon and other materials. Significant markets may develop for such materials, particularly in the semiconductor industry

  17. The assisting system for uranium enrichment plant operation

    International Nuclear Information System (INIS)

    Nakazawa, Hiroaki; Yamamoto, Fumio

    1990-01-01

    We have been developing an operation assisting system, partially supported by AI system, for uranium enrichment plant. The AI system is a proto-type system aiming a final one which can be applied to any future large uranium enrichment plant and also not only to specific operational area but also to complex and multi-phenomenon operational area. An existing AI system, for example facility diagnostic system that utilizes the result of CCT analysis as knowledge base, has weakness in flexibility and potentiality. To build AI system, we have developed the most suitable knowledge representations using deep knowledge for each facility or operation of uranium enrichment plant. This paper describes our AI proto-type system adopting several knowledge representations that can represent an uranium enrichment plant's operation with deep knowledge. (author)

  18. A strict anaerobic extreme thermophilic hydrogen-producing culture enriched from digested household waste

    DEFF Research Database (Denmark)

    Karakashev, Dimitar Borisov; Kotay, Shireen Meher; Trably, Eric

    2009-01-01

    The aim of this study was to enrich, characterize and identify strict anaerobic extreme thermophilic hydrogen (H-2) producers from digested household solid wastes. A strict anaerobic extreme thermophilic H-2 producing bacterial culture was enriched from a lab-scale digester treating household...... wastes at 70 degrees C. The enriched mixed culture consisted of two rod-shaped bacterial members growing at an optimal temperature of 80 degrees C and an optimal pH 8.1. The culture was able to utilize glucose, galactose, mannose, xylose, arabinose, maltose, sucrose, pyruvate and glycerol as carbon...... sources. Growth on glucose produced acetate, H-2 and carbon dioxide. Maximal H-2 production rate on glucose was 1.1 mmol l(-1) h(-1) with a maximum H-2 yield of 1.9 mole H-2 per mole glucose. 16S ribosomal DNA clone library analyses showed that the culture members were phylogenetically affiliated...

  19. Distribution of uranium supply and enrichment

    International Nuclear Information System (INIS)

    Bamford, F.W.

    1982-01-01

    Uranium supply and demand is examined from the perspective of companies in the uranium hexafluoride (UF6) conversion business whose main interest is their sources of uranium supply and UF6 destinations because of transportation costs. Because of the variations in yellowcake transport, charges for conversion, and UF6 transport costs, most converters don't have standard prices. Companies try to look ahead to determine patterns of supplies and delivery points when they analyze the market and estimate future prices. Market analyses must take into account the purchasing policies of utilities around the world. The presentation shows North America supplying about 40% of world uranium, with about 13% of the enrichment done elsewhere. It also shows North American converters getting 53% of the business, but that will require importing uranium from outside North America. 6 tables

  20. Calculation of the fissile mass of a graphite moderated critical assembly using 93% enriched uranium

    International Nuclear Information System (INIS)

    Correa, F.; Marzo, M.A.S.; Collussi, I.; Ferreira, A.C.A.

    1976-01-01

    The critical mass of uranium has been calculated for a graphite moderated set fueled with 93% enriched uranium to be mounted on the Instituto de Energia Atomica split table Zero Power Reactor. The core composition was optimized to permit the maximum number of configurations to be studied. Analysis of three core compositions shows that 8 Kg of uranium enriched to 93% - U-235 (by weight) and 100 Kg of thorium would be sufficient for criticality experiments [pt

  1. Uranium enrichment techniques

    International Nuclear Information System (INIS)

    Hamdoun, N.A.

    2007-01-01

    This article includes an introduction about the isotopes of natural uranium, their existence and the difficulty of the separation between them. Then it goes to the details of a number of methods used to enrich uranium: Gaseous Diffusion method, Electromagnetic method, Jet method, Centrifugal method, Chemical method, Laser method and Plasma method.

  2. Enriching the Catalog

    Science.gov (United States)

    Tennant, Roy

    2004-01-01

    After decades of costly and time-consuming effort, nearly all libraries have completed the retrospective conversion of their card catalogs to electronic form. However, bibliographic systems still are really not much more than card catalogs on wheels. Enriched content that Amazon.com takes for granted--such as digitized tables of contents, cover…

  3. Optimal set of selected uranium enrichments that minimizes blending consequences

    International Nuclear Information System (INIS)

    Nachlas, J.A.; Kurstedt, H.A. Jr.; Lobber, J.S. Jr.

    1977-01-01

    Identities, quantities, and costs associated with producing a set of selected enrichments and blending them to provide fuel for existing reactors are investigated using an optimization model constructed with appropriate constraints. Selected enrichments are required for either nuclear reactor fuel standardization or potential uranium enrichment alternatives such as the gas centrifuge. Using a mixed-integer linear program, the model minimizes present worth costs for a 39-product-enrichment reference case. For four ingredients, the marginal blending cost is only 0.18% of the total direct production cost. Natural uranium is not an optimal blending ingredient. Optimal values reappear in most sets of ingredient enrichments

  4. Tritium enrichment of environmental waters by electrolysis: Development of cathodes exhibiting high isotopic separation and precise measurement of tritium enrichment factors

    International Nuclear Information System (INIS)

    Taylor, C.B.

    1976-01-01

    Equations are developed for the estimation of tritium enrichment in batch, continuous feed and periodic addition electrolysis cells. Optimum enrichment and minimum variability is obtained using developed cathode surfaces which catalyse the separation of tritium, as exhibited by the results of experiments using mild steel cathodes with NaOH electrolyte. The equations and various simple refinements of technique are applied to the determination of tritium enrichment factors by the spike cell method: for batch cells the standard errors are less than 1%. (author)

  5. Uranium enrichment : global view and Brazilian perspectives

    International Nuclear Information System (INIS)

    Zouain, D.M.; Sakamoto, L.H.

    1981-12-01

    A global view of isotope enrichment involving a general description of process (technical-economical aspects and policy) and status in developing countries is done. An enrichment demand in function of the Brazilian Nuclear Program is evaluated, analyzing a probable market and a low market. The perspectives to attend this demand, are studied. (E.G.) [pt

  6. Optimization of axial enrichment distribution for BWR fuels using scoping libraries and block coordinate descent method

    Energy Technology Data Exchange (ETDEWEB)

    Tung, Wu-Hsiung, E-mail: wstong@iner.gov.tw; Lee, Tien-Tso; Kuo, Weng-Sheng; Yaur, Shung-Jung

    2017-03-15

    Highlights: • An optimization method for axial enrichment distribution in a BWR fuel was developed. • Block coordinate descent method is employed to search for optimal solution. • Scoping libraries are used to reduce computational effort. • Optimization search space consists of enrichment difference parameters. • Capability of the method to find optimal solution is demonstrated. - Abstract: An optimization method has been developed to search for the optimal axial enrichment distribution in a fuel assembly for a boiling water reactor core. The optimization method features: (1) employing the block coordinate descent method to find the optimal solution in the space of enrichment difference parameters, (2) using scoping libraries to reduce the amount of CASMO-4 calculation, and (3) integrating a core critical constraint into the objective function that is used to quantify the quality of an axial enrichment design. The objective function consists of the weighted sum of core parameters such as shutdown margin and critical power ratio. The core parameters are evaluated by using SIMULATE-3, and the cross section data required for the SIMULATE-3 calculation are generated by using CASMO-4 and scoping libraries. The application of the method to a 4-segment fuel design (with the highest allowable segment enrichment relaxed to 5%) demonstrated that the method can obtain an axial enrichment design with improved thermal limit ratios and objective function value while satisfying the core design constraints and core critical requirement through the use of an objective function. The use of scoping libraries effectively reduced the number of CASMO-4 calculation, from 85 to 24, in the 4-segment optimization case. An exhausted search was performed to examine the capability of the method in finding the optimal solution for a 4-segment fuel design. The results show that the method found a solution very close to the optimum obtained by the exhausted search. The number of

  7. The gas centrifuge, uranium enrichment and nuclear proliferation

    International Nuclear Information System (INIS)

    Chapman, A.

    1988-01-01

    The author considers the consequences for controlling nuclear proliferation of the emergence of the gas centrifuge method for enriching uranium and succeeds in the difficult and delicate task of saying enough about gas centrifuge techniques for readers to judge, what may be involved in fully embracing gas centrifuge enrichment within the constraints of an anti-proliferation strategy, whilst at the same time saying nothing that could be construed as encouraging an interest in the gas centrifuge route to highly enriched uranium where none had before existed. (author)

  8. Enrichment of Zinc in Galactic Chemodynamical Evolution Models

    Science.gov (United States)

    Hirai, Yutaka; Saitoh, Takayuki R.; Ishimaru, Yuhri; Wanajo, Shinya

    2018-03-01

    The heaviest iron-peak element Zinc (Zn) has been used as an important tracer of cosmic chemical evolution. Spectroscopic observations of the metal-poor stars in Local Group galaxies show an increasing trend of [Zn/Fe] ratios toward lower metallicity. However, the enrichment of Zn in galaxies is not well understood due to poor knowledge of astrophysical sites of Zn, as well as metal mixing in galaxies. Here we show possible explanations for the observed trend by taking into account electron-capture supernovae (ECSNe) as one of the sources of Zn in our chemodynamical simulations of dwarf galaxies. We find that the ejecta from ECSNe contribute to stars with [Zn/Fe] ≳ 0.5. We also find that scatters of [Zn/Fe] in higher metallicities originate from the ejecta of type Ia supernovae. On the other hand, it appears difficult to explain the observed trends if we do not consider ECSNe as a source of Zn. These results come from an inhomogeneous spatial metallicity distribution due to the inefficiency of the metal mixing. We find that the optimal value of the scaling factor for the metal diffusion coefficient is ∼0.01 in the shear-based metal mixing model in smoothed particle hydrodynamics simulations. These results suggest that ECSNe could be one of the contributors of the enrichment of Zn in galaxies.

  9. Study on Characteristics of Co-firing Ammonia/Methane Fuels under Oxygen Enriched Combustion Conditions

    Science.gov (United States)

    Xiao, Hua; Wang, Zhaolin; Valera-Medina, Agustin; Bowen, Philip J.

    2018-06-01

    Having a background of utilising ammonia as an alternative fuel for power generation, exploring the feasibility of co-firing ammonia with methane is proposed to use ammonia to substitute conventional natural gas. However, improvement of the combustion of such fuels can be achieved using conditions that enable an increase of oxygenation, thus fomenting the combustion process of a slower reactive molecule as ammonia. Therefore, the present study looks at oxygen enriched combustion technologies, a proposed concept to improve the performance of ammonia/methane combustion. To investigate the characteristics of ammonia/methane combustion under oxygen enriched conditions, adiabatic burning velocity and burner stabilized laminar flame emissions were studied. Simulation results show that the oxygen enriched method can help to significantly enhance the propagation of ammonia/methane combustion without changing the emission level, which would be quite promising for the design of systems using this fuel for practical applications. Furthermore, to produce low computational-cost flame chemistry for detailed numerical analyses for future combustion studies, three reduced combustion mechanisms of the well-known Konnov's mechanism were compared in ammonia/methane flame simulations under practical gas turbine combustor conditions. Results show that the reduced reaction mechanisms can provide good results for further analyses of oxygen enriched combustion of ammonia/methane. The results obtained in this study also allow gas turbine designers and modellers to choose the most suitable mechanism for further combustion studies and development.

  10. Dietary fatty acid enrichment increases egg size and quality of yellow seahorse Hippocampus kuda.

    Science.gov (United States)

    Saavedra, M; Masdeu, M; Hale, P; Sibbons, C M; Holt, W V

    2014-02-01

    Seahorses populations in the wild have been declining and to restore them a better knowledge of seahorse reproduction is required. This study examines the effect of dietary quality on seahorse fecundity and egg quality. Two different diets were tested with Hippocampus kuda females: frozen mysis (control) and frozen mysis enriched with a liposome spray containing essential fatty acids. Diets were given to females (two groups of five) over a seven week period. After this period, males (fed the control diet) and females were paired and the eggs dropped by the females were collected. Fatty acid profile were analysed and eggs were counted and measured. Results showed that females fed on enriched mysis had larger eggs and that these had a higher content of total polyunsaturated fatty acids. The size of the egg was especially affected in the first spawn, where egg size for females fed the enriched diet was significantly higher than the egg size from control females. This effect was reduced in the following spawning where no significant differences were found. Egg size is an important quality descriptor as seahorse juveniles originating from smaller eggs and/or eggs of poor quality will have less chances of overcoming adverse conditions in the wild and consequently have lower survival and growth rates. This study shows that enriching frozen mysis with polyunsaturated fatty acids increases egg size and egg quality of H. kuda. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. Enriched Water-H2 18O Purification to be Used in Routine 18FDG Production

    International Nuclear Information System (INIS)

    Al Rayyes, A.H.

    2009-01-01

    Oxygen-18 enriched water has been recovered from IBA (Ion Beam Applications) recovery system followed by purification and then used in the production of 18 F-. The purification process has been carried out by irradiation with UV followed by a distillation under vacuum. After purification, 95% of water is recovered and organic compounds, radioisotopes, trace metals and gases are eliminated efficiently. Results show that there are no significant differences in (2-deoxy-2-[ 18 F]fluoro-D-glucose ([ 18 F]FDG) production yield using purified water by the proposed method and new enriched water. Tritium was detected in the irradiated enriched water. Contamination precautions during purification should be considered. Tritium was not present in 18 FDG or Na- 18 F final products. (author)

  12. The evolution of the enriched uranium markets

    International Nuclear Information System (INIS)

    Arnaiz, J.; Moleres, C.; Tarin, F.

    2004-01-01

    This paper deals with the evolution of the enriched uranium component markets (uranium concentrates, conversion and enrichment), starting with the situation of historically low prices that occurred during 2000. The situation that has been reached as on December 2003, when the concentrates and conversion markets were 44% and 70% (current US$) respectively, and the enrichment prices 30%, higher, is analysed. Finally, the negative impact of the 90's depressed prices, due to abundant alternative sources of uranium components, on the primary production of all three components and, as a conclusion, the impact of the new situation on the transport logistics, and the need of appropriate economic conditions to make the future primary production sustainable, is commented. (Author)

  13. Virtual Environmental Enrichment through Video Games Improves Hippocampal-Associated Memory

    Science.gov (United States)

    Clemenson, Gregory D.

    2015-01-01

    The positive effects of environmental enrichment and their neural bases have been studied extensively in the rodent (van Praag et al., 2000). For example, simply modifying an animal's living environment to promote sensory stimulation can lead to (but is not limited to) enhancements in hippocampal cognition and neuroplasticity and can alleviate hippocampal cognitive deficits associated with neurodegenerative diseases and aging. We are interested in whether these manipulations that successfully enhance cognition (or mitigate cognitive decline) have similar influences on humans. Although there are many “enriching” aspects to daily life, we are constantly adapting to new experiences and situations within our own environment on a daily basis. Here, we hypothesize that the exploration of the vast and visually stimulating virtual environments within video games is a human correlate of environmental enrichment. We show that video gamers who specifically favor complex 3D video games performed better on a demanding recognition memory task that assesses participants' ability to discriminate highly similar lure items from repeated items. In addition, after 2 weeks of training on the 3D video game Super Mario 3D World, naive video gamers showed improved mnemonic discrimination ability and improvements on a virtual water maze task. Two control conditions (passive and training in a 2D game, Angry Birds), showed no such improvements. Furthermore, individual performance in both hippocampal-associated behaviors correlated with performance in Super Mario but not Angry Birds, suggesting that how individuals explored the virtual environment may influence hippocampal behavior. SIGNIFICANCE STATEMENT The hippocampus has long been associated with episodic memory and is commonly thought to rely on neuroplasticity to adapt to the ever-changing environment. In animals, it is well understood that exposing animals to a more stimulating environment, known as environmental enrichment, can

  14. Enrichment measurement in TRIGA type fuels

    International Nuclear Information System (INIS)

    Aguilar H, F.; Mazon R, R.

    2001-05-01

    The Department of Energy of the United States of North America, through the program 'Idaho Operations Nuclear Spent Fuel Program' of the Idaho National Engineering and Environmental Laboratory (INEEL), in Idaho Falls; Idaho USA, hires to Global Technologies Inc. (GTI) to develop a prototype device of detection enrichment uranium (DEU Detection of Enrichment of Uranium) to determine quantitatively the enrichment in remainder U-235 in a TRIGA fuel element at the end of it useful life. The characteristics of the prototype developed by GTI are the following ones: It allows to carry out no-destructive measurements of TRIGA type fuel. Easily transportable due to that reduced of it size. The determination of the enrichment (in grams of U-235) it is obtained with a precision of 5%. The National Institute of Nuclear Research (ININ), in its facilities of the Nuclear Center of Mexico, it has TRIGA type fuel of high and low enrichment (standard and FLIP) fresh and with burnt, it also has the infrastructure (hot cells, armor-plating of transport, etc) and qualified personnel to carry out the necessary maneuvers to prove the operation of the DEU prototype. For this its would be used standard type fuel elements and FLIP, so much fresh as with certain burnt one. In the case of the fresh fuels the measurement doesn't represent any risk, the fuels before and after the measurement its don't contain a quantity of fission products that its represent a radiological risk in its manipulation; but in the case of the fuels with burnt the handling of the same ones represents an important radiological risk reason why for its manipulation it was used the transport armor-plating and the hot cells. (Author)

  15. DOE hands over uranium enrichment duties to government corporation

    International Nuclear Information System (INIS)

    Simpson, J.

    1993-01-01

    In an effort to renew the United States' competitiveness in the world market for uranium enrichment services, the Department of Energy (DOE) is turning over control of its Paducah, KY, and Portsmouth, OH, enrichment facilities to a for-profit organization, the United States Enrichment Corp. (USEC), which was created by last year's Energy Policy Act. William H. Timbers, Jr., a former investment banker who was appointed acting CEO in March, said the Act's mandate will mean more competitive prices for enriched reactor fuel and greater responsiveness to utility customers. As a government corporation, USEC, with current annual revenues estimated at $1.5 billion, will no longer be part of the federal budget appropriations process, but will use business management techniques, set market-based prices for enriched uranium, and pay annual dividends to the US Treasury-its sole stockholder-from earnings. The goal is to finish privatizing the corporation within two years, and to sell its stock to investors for an estimated $1 to $3 billion. USEC's success will depend in part on developing short- and long-term marketing plants to help stanch the flow of enriched-uranium customers to foreign suppliers. (DOE already has received notice from a number of US utilities that they want to be let out of their long-term enrichment contracts as they expire over the next several years).USEC's plans likely will include exploring new joint ventures with other businesses in the nuclear fuel cycle-such as suppliers, fabricators, and converters-and offering a broader range of enrichment services than DOE provided. The corporation will have to be responsive to utilities on an individual basis

  16. City model enrichment

    Science.gov (United States)

    Smart, Philip D.; Quinn, Jonathan A.; Jones, Christopher B.

    The combination of mobile communication technology with location and orientation aware digital cameras has introduced increasing interest in the exploitation of 3D city models for applications such as augmented reality and automated image captioning. The effectiveness of such applications is, at present, severely limited by the often poor quality of semantic annotation of the 3D models. In this paper, we show how freely available sources of georeferenced Web 2.0 information can be used for automated enrichment of 3D city models. Point referenced names of prominent buildings and landmarks mined from Wikipedia articles and from the OpenStreetMaps digital map and Geonames gazetteer have been matched to the 2D ground plan geometry of a 3D city model. In order to address the ambiguities that arise in the associations between these sources and the city model, we present procedures to merge potentially related buildings and implement fuzzy matching between reference points and building polygons. An experimental evaluation demonstrates the effectiveness of the presented methods.

  17. GSL-enriched membrane microdomains in innate immune responses.

    Science.gov (United States)

    Nakayama, Hitoshi; Ogawa, Hideoki; Takamori, Kenji; Iwabuchi, Kazuhisa

    2013-06-01

    Many pathogens target glycosphingolipids (GSLs), which, together with cholesterol, GPI-anchored proteins, and various signaling molecules, cluster on host cell membranes to form GSL-enriched membrane microdomains (lipid rafts). These GSL-enriched membrane microdomains may therefore be involved in host-pathogen interactions. Innate immune responses are triggered by the association of pathogens with phagocytes, such as neutrophils, macrophages and dendritic cells. Phagocytes express a diverse array of pattern-recognition receptors (PRRs), which sense invading microorganisms and trigger pathogen-specific signaling. PRRs can recognize highly conserved pathogen-associated molecular patterns expressed on microorganisms. The GSL lactosylceramide (LacCer, CDw17), which binds to various microorganisms, including Candida albicans, is expressed predominantly on the plasma membranes of human mature neutrophils and forms membrane microdomains together with the Src family tyrosine kinase Lyn. These LacCer-enriched membrane microdomains can mediate superoxide generation, migration, and phagocytosis, indicating that LacCer functions as a PRR in innate immunity. Moreover, the interactions of GSL-enriched membrane microdomains with membrane proteins, such as growth factor receptors, are important in mediating the physiological properties of these proteins. Similarly, we recently found that interactions between LacCer-enriched membrane microdomains and CD11b/CD18 (Mac-1, CR3, or αMβ2-integrin) are significant for neutrophil phagocytosis of non-opsonized microorganisms. This review describes the functional role of LacCer-enriched membrane microdomains and their interactions with CD11b/CD18.

  18. Ranking metrics in gene set enrichment analysis: do they matter?

    Science.gov (United States)

    Zyla, Joanna; Marczyk, Michal; Weiner, January; Polanska, Joanna

    2017-05-12

    There exist many methods for describing the complex relation between changes of gene expression in molecular pathways or gene ontologies under different experimental conditions. Among them, Gene Set Enrichment Analysis seems to be one of the most commonly used (over 10,000 citations). An important parameter, which could affect the final result, is the choice of a metric for the ranking of genes. Applying a default ranking metric may lead to poor results. In this work 28 benchmark data sets were used to evaluate the sensitivity and false positive rate of gene set analysis for 16 different ranking metrics including new proposals. Furthermore, the robustness of the chosen methods to sample size was tested. Using k-means clustering algorithm a group of four metrics with the highest performance in terms of overall sensitivity, overall false positive rate and computational load was established i.e. absolute value of Moderated Welch Test statistic, Minimum Significant Difference, absolute value of Signal-To-Noise ratio and Baumgartner-Weiss-Schindler test statistic. In case of false positive rate estimation, all selected ranking metrics were robust with respect to sample size. In case of sensitivity, the absolute value of Moderated Welch Test statistic and absolute value of Signal-To-Noise ratio gave stable results, while Baumgartner-Weiss-Schindler and Minimum Significant Difference showed better results for larger sample size. Finally, the Gene Set Enrichment Analysis method with all tested ranking metrics was parallelised and implemented in MATLAB, and is available at https://github.com/ZAEDPolSl/MrGSEA . Choosing a ranking metric in Gene Set Enrichment Analysis has critical impact on results of pathway enrichment analysis. The absolute value of Moderated Welch Test has the best overall sensitivity and Minimum Significant Difference has the best overall specificity of gene set analysis. When the number of non-normally distributed genes is high, using Baumgartner

  19. Enrichment and immobilization of sulfide removal microbiota applied for environmental biological remediation of aquaculture area

    International Nuclear Information System (INIS)

    Zhao, Yang-Guo; Zheng, Yu; Tian, Weijun; Bai, Jie; Feng, Gong; Guo, Liang; Gao, Mengchun

    2016-01-01

    To remove sulfide in the deteriorating aquaculture sediment and water, sulfide-oxidizing microbiota was enriched from Jiaozhou Bay, China, by using sulfide-rich medium. Composition and structure of microbial communities in the enrichments were investigated by 16S rDNA molecular biotechniques. Results showed that microbial community structure continuously shifted and the abundance of sulfate reducing bacteria, i.e., Desulfobacterium, Desulfococcus and Desulfobacca apparently declined. Several halophile genera, Vibrio, Marinobacter, Pseudomonas, Prochlorococcus, Pediococcus and Thiobacillus predominated finally in the microbiota. The enriched microbiota was capable of removing a maximum of 1000 mg/L sulfide within 12 h with 10% inoculum at pH 7.0, 20–30 °C. After immobilized, the microbiota presented excellent resistance to impact and could completely remove 600 mg/L sulfide in 12 h. Moreover, the immobilized microbiota recovered well even recycled for five times. In conclusion, the immobilized sulfide-removing microbiota showed a quite promising application for biological restoring of sulfide-rich aquaculture environment. - Highlights: • A sulfide-oxidizing microbiota successfully enriched from aquaculture sediment. • Microbiota dominated by Vibrio, Marinobacter, Pseudomonas and Thiobacillus spp. • Sulfide-oxidizing microbiota removed sulfide at an average rate of 100 mg/(L·h). • Immobilized microbiota removed over 85% of sulfide even recycled for five times.

  20. Evaluation of economical at a uranium enrichment demonstration plant

    International Nuclear Information System (INIS)

    Sugitsue, Noritake

    2001-01-01

    In this report, the economy of technical achievement apply in the uranium enrichment demonstration plant is evaluated. From the evaluation, it can be concluded that the expected purpose was achieved because there was a definite economic prospect to commercial plant. The benefit analysis of thirteen years operation of the uranium enrichment demonstration plant also provides a financial aspect of the uranium enrichment business. Therefore, the performance, price and reliability of the centrifuge is an important factor in the uranium enrichment business. And the continuous development of a centrifuge while considering balance with the development cost is necessary for the business in the future. (author)

  1. Multi-layer solid-phase extraction and evaporation-enrichment methods for polar organic chemicals from aqueous matrices.

    Science.gov (United States)

    Köke, Niklas; Zahn, Daniel; Knepper, Thomas P; Frömel, Tobias

    2018-03-01

    Analysis of polar organic chemicals in the aquatic environment is exacerbated by the lack of suitable and widely applicable enrichment methods. In this work, we assessed the suitability of a novel combination of well-known solid-phase extraction (SPE) materials in one cartridge as well as an evaporation method and for the enrichment of 26 polar model substances (predominantly log D evaporation method were investigated for the recovery and matrix effects of the model substances and analyzed with hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS). In total, 65% of the model substances were amenable (> 10% recovery) to the mlSPE method with a mean recovery of 76% while 73% of the model substances were enriched with the evaporation method achieving a mean recovery of 78%. Target and non-target screening comparison of both methods with a frequently used reversed-phase SPE method utilizing "hydrophilic and lipophilic balanced" (HLB) material was performed. Target analysis showed that the mlSPE and evaporation method have pronounced advantages over the HLB method since the HLB material retained only 30% of the model substances. Non-target screening of a ground water sample with the investigated enrichment methods showed that the median retention time of all detected features on a HILIC system decreased in the order mlSPE (3641 features, median t R 9.7 min), evaporation (1391, 9.3 min), HLB (4414, 7.2 min), indicating a higher potential of the described methods to enrich polar analytes from water compared with HLB-SPE. Graphical abstract Schematic of the method evaluation (recovery and matrix effects) and method comparison (target and non-target analysis) of the two investigated enrichment methods for very polar chemicals in aqueousmatrices.

  2. Enriching Orphans’ Potentials through Interpersonal and Intrapersonal Intelligence Enrichment Activities

    Directory of Open Access Journals (Sweden)

    Nurulwahida Hj Azid

    2016-01-01

    Full Text Available Orphans are considered a minority and they should be given a greater emphasis so that they do not feel left out and can build their own lives without a sense of humility. This does not mean that the orphans should be pampered instead they should be given the confidence and motivation to strive for success in later life. Humility among orphans can be associated with interpersonal and intrapersonal intelligences. This study aims to evaluate the impact of problem-solving activity treatment based on the interpersonal and intrapersonal intelligences. 46 students from two orphanages were involved as the treatment group. The research design used was a one-group pretest-posttest design applied through a combination of quantitative and qualitative approaches. Enrichment activities that provided interpersonal and intrapersonal skills as evidenced in this study should be carried out regularly at orphanages. Our study has proven that orphans‟ rights to learn cannot be neglected and „no child left behind „policy needs to be carried through by everybody involved with orphans‟ well-being. Teachers and carers need to be trained to use these enrichment activities at their orphanages to help maximize the orphans‟ potentials.

  3. Integrated Enrichment Analysis of Variants and Pathways in Genome-Wide Association Studies Indicates Central Role for IL-2 Signaling Genes in Type 1 Diabetes, and Cytokine Signaling Genes in Crohn's Disease

    Science.gov (United States)

    Carbonetto, Peter; Stephens, Matthew

    2013-01-01

    Pathway analyses of genome-wide association studies aggregate information over sets of related genes, such as genes in common pathways, to identify gene sets that are enriched for variants associated with disease. We develop a model-based approach to pathway analysis, and apply this approach to data from the Wellcome Trust Case Control Consortium (WTCCC) studies. Our method offers several benefits over existing approaches. First, our method not only interrogates pathways for enrichment of disease associations, but also estimates the level of enrichment, which yields a coherent way to promote variants in enriched pathways, enhancing discovery of genes underlying disease. Second, our approach allows for multiple enriched pathways, a feature that leads to novel findings in two diseases where the major histocompatibility complex (MHC) is a major determinant of disease susceptibility. Third, by modeling disease as the combined effect of multiple markers, our method automatically accounts for linkage disequilibrium among variants. Interrogation of pathways from eight pathway databases yields strong support for enriched pathways, indicating links between Crohn's disease (CD) and cytokine-driven networks that modulate immune responses; between rheumatoid arthritis (RA) and “Measles” pathway genes involved in immune responses triggered by measles infection; and between type 1 diabetes (T1D) and IL2-mediated signaling genes. Prioritizing variants in these enriched pathways yields many additional putative disease associations compared to analyses without enrichment. For CD and RA, 7 of 8 additional non-MHC associations are corroborated by other studies, providing validation for our approach. For T1D, prioritization of IL-2 signaling genes yields strong evidence for 7 additional non-MHC candidate disease loci, as well as suggestive evidence for several more. Of the 7 strongest associations, 4 are validated by other studies, and 3 (near IL-2 signaling genes RAF1, MAPK14

  4. Modeling Profiles and Signatures of Enrichments

    Science.gov (United States)

    Ali, A.; Qualls, C.; Lucas, S. G.; Lombari, G.; Appenzeller, O.

    2014-12-01

    Anthropogenic and geochemical enrichment of soils and living matter have been well documented 1, 2, 3.Here we report on geochemical, anthropogenic and biological enrichments with heavy metals in Modern Peru and compared this to Modern and ancient data from New Mexico, USA. We established a signature derived from the quantities of 25 metals in various biological, fossil and soil materials. We also speculate that human adaptation to mercury toxicity may occur in remarkably short time spans during the Holocene. We found mercury concentrations in Modern pigeon feathers and llama wool from free foraging birds and animals in Albuquerque, NM, ranging from 0.006 to 0.019 mg/Kg of tissue. The values for Modern Peru ranged from 22.0 to 556 mg/Kg for the same tissues. We discovered, in 64 million-year-old fossilized plants from New Mexico (Paleocene Nacimiento Formation, San Juan Basin), a mercury concentration of 1.11 mg/Kg of fossil, whereas Modern plant material from the Rio Grande Basin in New Mexico contained no mercury. Profiling of metal content of these samples suggests that mercury is a proxy for anthropogenic rather than geochemical enrichment in the localities we examined. We found no overt signs of mercury toxicity in contemporaneous inhabitants of Huancavelica4, Peru; one of the ten most mercury-polluted places in the world and the mercury concentration in their hair is well below modern admissible levels. However, assessment of their annual scalp hair growth-rate showed marked reduction in growth (~ 5cm/yr) versus ~ 16cm/year for normal scalp hair from other continents4. This is consistent with a toxic effect of heavy metals on human metabolism and especially autonomic nervous system function in Huancavelica, Peru. Contemporaneous anthropogenic activities are known to increase heavy metal content in the biosphere with potentially toxic effects on humans. However, signs of human evolutionary adaptation to such toxins might already be evident in Peru4.

  5. Data analysis for neutron monitoring in an enrichment facility

    International Nuclear Information System (INIS)

    Markin, J.T.; Stewart, J.E.; Goldman, A.S.

    1982-01-01

    Area monitoring of neutron radiation to detect high-enriched uranium production is a potential strategy for inspector verification of operations in the cascade area of a centrifuge enrichment facility. This paper discusses the application of statistical filtering and hypothesis testing procedures to experimental data taken in an enrichment facility. The results demonstrate that these data analysis methods can enhance detection of facility misoperation by neutron monitoring

  6. Enriching stable isotopes: Alternative use for Urenco technology

    International Nuclear Information System (INIS)

    Rakhorst, H.; de Jong, P.G.T.; Dawson, P.D.

    1996-01-01

    The International Urenco Group utilizes a technologically advanced centrifuge process to enrich uranium in the fissionable isotope 235 U. The group operates plants in the United Kingdom, the Netherlands, and Germany and currently holds a 10% share of the multibillion dollar world enrichment market. In the early 1990s, Urenco embarked on a strategy of building on the company's uniquely advanced centrifuge process and laser isotope separation (LIS) experience to enrich nonradioactive isotopes colloquially known as stable isotopes. This paper summarizes the present status of Urenco's stable isotopes business

  7. The Enriched Effect Calculus: Syntax and Semantics

    DEFF Research Database (Denmark)

    Møgelberg, Rasmus Ejlers; Simpson, Alex; Egger, Jeff

    2014-01-01

    This article introduces the enriched effect calculus, which extends established type theories for computational effects with primitives from linear logic. The new calculus provides a formalism for expressing linear aspects of computational effects; e.g. the linear usage of imperative features....... The second half of the article investigates models for the enriched effect calculus, based on enriched category theory. We give several examples of such models, relating them to models of standard effect calculi (such as those based on monads), and to models of intuitionistic linear logic. We also prove...

  8. Anaerobic degradation of benzene by enriched consortia with humic acids as terminal electron acceptors

    Energy Technology Data Exchange (ETDEWEB)

    Cervantes, Francisco J., E-mail: fjcervantes@ipicyt.edu.mx [Division de Ciencias Ambientales, Instituto Potosino de Investigacion Cientifica y Tecnologica (IPICyT), Camino a la Presa San Jose 2055, Col. Lomas 4a. Seccion, San Luis Potosi, SLP, 78216 Mexico (Mexico); Mancilla, Ana Rosa; Toro, E. Emilia Rios-del [Division de Ciencias Ambientales, Instituto Potosino de Investigacion Cientifica y Tecnologica (IPICyT), Camino a la Presa San Jose 2055, Col. Lomas 4a. Seccion, San Luis Potosi, SLP, 78216 Mexico (Mexico); Alpuche-Solis, Angel G.; Montoya-Lorenzana, Lilia [Division de Biologia Molecular, Instituto Potosino de Investigacion Cientifica y Tecnologica (IPICyT), Camino a la Presa San Jose 2055, Col. Lomas 4a. Seccion, San Luis Potosi, SLP, 78216 Mexico (Mexico)

    2011-11-15

    Highlights: {yields} Enriched consortia were able to couple the anaerobic degradation of benzene to the reduction of humic acids. {yields} Electron-equivalents derived from anaerobic benzene oxidation were highly recovered as reduced humic acids. {yields} Several species from classes {beta}-, {delta}- and {gamma}-Proteobacteria were enriched during the anaerobic degradation of benzene. - Abstract: The anaerobic degradation of benzene coupled to the reduction of humic acids (HA) was demonstrated in two enriched consortia. Both inocula were able to oxidize benzene under strict anaerobic conditions when the humic model compound, anthraquinone-2,6-disulfonate (AQDS), was supplied as terminal electron acceptor. An enrichment culture originated from a contaminated soil was also able to oxidize benzene linked to the reduction of highly purified soil humic acids (HPSHA). In HPSHA-amended cultures, 9.3 {mu}M of benzene were degraded, which corresponds to 279 {+-} 27 micro-electron equivalents ({mu}Eq) L{sup -1}, linked to the reduction of 619 {+-} 81 {mu}Eq L{sup -1} of HPSHA. Neither anaerobic benzene oxidation nor reduction of HPSHA occurred in sterilized controls. Anaerobic benzene oxidation did not occur in soil incubations lacking HPSHA. Furthermore, negligible reduction of HPSHA occurred in the absence of benzene. The enrichment culture derived from this soil was dominated by two {gamma}-Proteobacteria phylotypes. A benzene-degrading AQDS-reducing enrichment originated from a sediment sample showed the prevalence of different species from classes {beta}-, {delta}- and {gamma}-Proteobacteria. The present study provides clear quantitative demonstration of anaerobic degradation of benzene coupled to the reduction of HA.

  9. Anaerobic degradation of benzene by enriched consortia with humic acids as terminal electron acceptors

    International Nuclear Information System (INIS)

    Cervantes, Francisco J.; Mancilla, Ana Rosa; Toro, E. Emilia Rios-del; Alpuche-Solis, Angel G.; Montoya-Lorenzana, Lilia

    2011-01-01

    Highlights: → Enriched consortia were able to couple the anaerobic degradation of benzene to the reduction of humic acids. → Electron-equivalents derived from anaerobic benzene oxidation were highly recovered as reduced humic acids. → Several species from classes β-, δ- and γ-Proteobacteria were enriched during the anaerobic degradation of benzene. - Abstract: The anaerobic degradation of benzene coupled to the reduction of humic acids (HA) was demonstrated in two enriched consortia. Both inocula were able to oxidize benzene under strict anaerobic conditions when the humic model compound, anthraquinone-2,6-disulfonate (AQDS), was supplied as terminal electron acceptor. An enrichment culture originated from a contaminated soil was also able to oxidize benzene linked to the reduction of highly purified soil humic acids (HPSHA). In HPSHA-amended cultures, 9.3 μM of benzene were degraded, which corresponds to 279 ± 27 micro-electron equivalents (μEq) L -1 , linked to the reduction of 619 ± 81 μEq L -1 of HPSHA. Neither anaerobic benzene oxidation nor reduction of HPSHA occurred in sterilized controls. Anaerobic benzene oxidation did not occur in soil incubations lacking HPSHA. Furthermore, negligible reduction of HPSHA occurred in the absence of benzene. The enrichment culture derived from this soil was dominated by two γ-Proteobacteria phylotypes. A benzene-degrading AQDS-reducing enrichment originated from a sediment sample showed the prevalence of different species from classes β-, δ- and γ-Proteobacteria. The present study provides clear quantitative demonstration of anaerobic degradation of benzene coupled to the reduction of HA.

  10. Preparation of rat islet B-cell-enriched fractions by light-scatter flow cytometry

    International Nuclear Information System (INIS)

    Rabinovitch, A.; Russell, T.; Shienvold, F.; Noel, J.; Files, N.; Patel, Y.; Ingram, M.

    1982-01-01

    Flow cytometry has been examined as a method to separate islet cells into homogeneous subpopulations. Collagenase-isolated rat islets were dissociated into single cells and these were analyzed and sorted according to their low forward angle light scattering properties by using automated flow cytometry. Light scatter histograms showed two peaks of viable cells. Radioimmunoassay of hormone content in cell fractions collected across the the two peaks showed that glucagon-containing cells were concentrated towards the left side of the left peak and somatostatin-containing cells were concentrated towards the right side of the left peak, whereas insulin-containing cells were clearly enriched in the right peak. The B-cell-enriched fraction (90% B cells, 3% A cells, 2% D cells) exhibited significant insulin secretory responses to glucose (16.7 mM), and 3-isobutyl-1-methylxanthine (0.1 mM), during a 24-h culture period, and these responses were slightly greater than those observed in the original mixed islet cell preparation (66% B cells, 14% A cells, and 4% D cells). These results indicate that flow cytometry can be applied to sort pancreatic islet cells into populations enriched in specific endocrine cell types for further study of the functions of individual cell types

  11. The measurement of tritium in water samples with electrolytic enrichment using liquid scintillation counter

    Directory of Open Access Journals (Sweden)

    Janković Marija M.

    2012-01-01

    Full Text Available Tritium (3H present in the environment decreased in the last decades and nowadays it has low activity concentrations. Measurement of low-level tritium activities in natural waters, e. g. in precipitation, groundwater, and river water requires special techniques for water pretreatment and detection of low-level radioactivity. In order to increase the tritium concentration to an easily measurable level, electrolytic enrichment must be applied. This paper presents the enrichment method performed by electrolysis in a battery of 18 cells, giving an enrichment factor of 5.84 (calculated from 59 electrolyses. The calculated mean values of the separation factor and enrichment parameter were 4.10 and 0.84, respectively. Results for tritium activity in precipitation and surface water collected in Belgrade during 2008 and 2009 are presented. The Radiation and Environmental Protection Department of the Vinča Institute of Nuclear Sciences, participated in the IAEA TRIC2008 international intercomparison exercise. The participation in the intercomparisons for any laboratory doing low-level 3H measurements in the waters is very important and useful. It is considered the best way to check the entire procedure and methods of the measurements and the reliability of the standard used. The analysis of the reported 3H activity results showed that all results for five intercomparison samples, for which electrolytic enrichment were applied prior to the 3H measurement, are acceptable.

  12. Distribution and ecological relevance of fine sediments in organic-enriched lagoons: The case study of the Cabras lagoon (Sardinia, Italy)

    Energy Technology Data Exchange (ETDEWEB)

    Magni, P. [CNR-IAMC, National Research Council - Institute for Coastal Marine Environment Localita Sa Mardini, Torregrande, 09072 Oristano (Italy); International Marine Centre, Localita Sa Mardini, Torregrande, 09072 Oristano (Italy)], E-mail: paolo.magni@iamc.cnr.it; De Falco, G. [CNR-IAMC, National Research Council - Institute for Coastal Marine Environment Localita Sa Mardini, Torregrande, 09072 Oristano (Italy); International Marine Centre, Localita Sa Mardini, Torregrande, 09072 Oristano (Italy); Como, S. [International Marine Centre, Localita Sa Mardini, Torregrande, 09072 Oristano (Italy); Casu, D. [Dip. di Botanica ed Ecologia vegetale, Universita di Sassari, 07100 Sassari (Italy); Floris, A. [Dip. di Zoologia e Genetica evoluzionistica, Universita di Sassari, 07100 Sassari (Italy); Petrov, A.N. [Institute of Biology of the Southern Seas NASU, 99011 Sevastopol (Ukraine); Castelli, A. [Dip. di Biologia, Universita di Pisa, 56126 Pisa (Italy); Perilli, A. [CNR-IAMC, National Research Council - Institute for Coastal Marine Environment Localita Sa Mardini, Torregrande, 09072 Oristano (Italy); International Marine Centre, Localita Sa Mardini, Torregrande, 09072 Oristano (Italy)

    2008-03-15

    In organic-enriched sedimentary systems, like many Mediterranean coastal lagoons, a detailed analysis of sediment grain size composition and partitioning within the muds is crucial to investigate sedimentological trends related to both hydrodynamic energy and basin morphology. In these systems, sediment dynamics are particularly important because the partitioning and transport of fine sediments can strongly influence the redistribution and accumulation of large amounts of organic matter, and consequently the distribution of benthic assemblages and the trophic status and functioning of a lagoon. Nevertheless, studies on benthic-sediment relationships have been based mainly on a rather coarse analysis of sediment grain size features. In muddy systems, however, this approach may impede a proper evaluation of the relationships and effects of the distribution of fine sediment and organic matter on the biotic benthic components. Here we show that the distribution of sedimentary organic matter (OM) and total organic carbon (TOC) in the Cabras lagoon (Sardinia, Italy) can be explained (i.e., predicted) as a function of a nonlinear increase in the amount of the cohesive fraction of sediments ({<=}8 {mu}m grain size particles) and that this fraction strongly influences the structure, composition and distribution of macrobenthic assemblages. Even in such a homogeneously muddy system, characterized by 'naturally' occurring impoverished communities, impaired benthic assemblages were found at {<=}8 {mu}m, OM, TOC contents of about 77%, 11% and 3.5%, respectively. A review of studies conducted in Mediterranean coastal lagoons highlighted a lack of direct integrated analysis of sediment features and the biotic components. We suggest that, especially in organic-enriched coastal lagoons, monitoring programs should primarily investigate and consider the cohesive fraction of sediments in order to allow a better assessment of benthic-sediment relationships and ecological

  13. Air strikes on uranium enrichment plants as potential sources of radioecological danger

    Directory of Open Access Journals (Sweden)

    Živanov Dragan

    2007-01-01

    Full Text Available According to the Non Proliferation Treaty (NPT, the signatory countries are not forbidden to preform uranium enrichment for peaceful purposes. However, if there is a justified doubt that the uranium enrichment is performed with the aim to produce nuclear weapons, this certainly causes great concern. In this case, the international community can apply pressure to a certain country if it determines that the country does not want to cease activities of making its own nuclear weapons. The international community pressure on the country can be intesified until its political leadership is not made to question and cease all activities of producing nuclear weapons. This pressure can be political, economic, and as a last resort-military. As a gesture of goodwill the country can stop the uranium enrichment process. In this way, the country shows that it finally gives up the intention to produce nuclear weapons. However, when military pressure is applied, i.e. military strikes (air strikes for example on nuclear plants used for uranium enrichment, this certainly creates a risk of releasing radioactivity into the environment. That is why the aim of this paper is to signal this very fact. Using military force in these cases leads to additional radioactive contamination of the environment, so this way of solving conflicts should be avoided within the international community.

  14. Impacts of CO2 Enrichment on Productivity and Light Requirements of Eelgrass.

    Science.gov (United States)

    Zimmerman, R. C.; Kohrs, D. G.; Steller, D. L.; Alberte, R. S.

    1997-10-01

    Seagrasses, although well adapted for submerged existence, are CO2-limited and photosynthetically inefficient in seawater. This leads to high light requirements for growth and survival and makes seagrasses vulnerable to light limitation. We explored the long-term impact of increased CO2 availability on light requirements, productivity, and C allocation in eelgrass (Zostera marina L.). Enrichment of seawater CO2 increased photosynthesis 3-fold, but had no long-term impact on respiration. By tripling the rate of light-saturated photosynthesis, CO2 enrichment reduced the daily period of irradiance-saturated photosynthesis (Hsat) that is required for the maintenance of positive whole-plant C balance from 7 to 2.7 h, allowing plants maintained under 4 h of Hsat to perform like plants growing in unenriched seawater with 12 h of Hsat. Eelgrass grown under 4 h of Hsat without added CO2 consumed internal C reserves as photosynthesis rates and chlorophyll levels dropped. Growth ceased after 30 d. Leaf photosynthesis, respiration, chlorophyll, and sucrose-phosphate synthase activity of CO2-enriched plants showed no acclimation to prolonged enrichment. Thus, the CO2-stimulated improvement in photosynthesis reduced light requirements in the long term, suggesting that globally increasing CO2 may enhance seagrass survival in eutrophic coastal waters, where populations have been devastated by algal proliferation and reduced water-column light transparency.

  15. South Australia, uranium enrichment

    International Nuclear Information System (INIS)

    1976-02-01

    The Report sets out the salient data relating to the establishment of a uranium processing centre at Redcliff in South Australia. It is conceived as a major development project for the Commonwealth, the South Australian Government and Australian Industry comprising the refining and enrichment of uranium produced from Australian mines. Using the data currently available in respect of markets, demand, technology and possible financial return from overseas sales, the project could be initiated immediately with hexafluoride production, followed rapidly in stages by enrichment production using the centrifuge process. A conceptual development plan is presented, involving a growth pattern that would be closely synchronised with the mining and production of yellowcake. The proposed development is presented in the form of an eight-and-half-year programme. Costs in this Report are based on 1975 values, unless otherwise stated. (Author)

  16. TiO{sub 2}-enriched polymeric powder coatings support human mesenchymal cell spreading and osteogenic differentiation

    Energy Technology Data Exchange (ETDEWEB)

    Mozumder, Mohammad Sayem; Zhu, Jesse [Department of Chemical and Biochemical Engineering, University of Western Ontario, London, Ontario, N6A 5B9 (Canada); Perinpanayagam, Hiran, E-mail: Hiran.Perinpanayagam@schulich.uwo.ca [Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, N6A 5C1 (Canada)

    2011-06-15

    Novel polymeric powder coatings (PPC) were prepared by ultrafine powder coating technology and shown to support human mesenchymal cell attachment and growth. PPC surfaces enriched with nano-TiO{sub 2} (nTiO{sub 2}) showed enhanced cellular responses, and were compared to commercially pure titanium (cpTi). After cell attachment and growth, osteogenic differentiation and bone matrix formation ensures osseointegration for implantable biomaterials. Therefore, the objective of this study was to determine if mesenchymal cells grown on PPC could undergo osteogenic differentiation by inducing Runx2 and bone matrix proteins, and then initiate mineralization. Atomic force microscopy revealed intricate three-dimensional micro-topographies, and the measures of nano-roughness and porosity were similar for all PPC surfaces. Scanning electron microscopy showed that the cells attached and spread out over all of the surfaces. After 1 week in osteogenic media, RT-PCR analysis showed the induction of Runx2, the up-regulation of type I collagen, and the initial detection of alkaline phosphatase and bone sialoprotein. After 4 weeks, Alizarin Red staining showed mineral deposition. However, cell spreading and osteogenic differentiation were significantly (P < 0.05) higher on the cpTi controls than on the PPC surfaces. Furthermore, spreading and differentiation were consistently higher on the titanium-enriched PPC-2, -3 and -4 than on the titanium-free PPC-1. Therefore, despite the presence of complex micro-topographies and nano-features, titanium-enrichment enhanced the cellular response, and pure titanium still provided the best substrate. These findings confirm the cytocompatibility of these novel polymeric coatings and suggest that titanium-enrichment and nTiO{sub 2} additives may enhance their performance.

  17. Ningyo Toge uranium enrichment pilot plant comes into full

    International Nuclear Information System (INIS)

    1982-01-01

    The uranium enrichment pilot plant of the Power Reactor and Nuclear Fuel Development Corporation at Ningyo Toge went into full operation on March 26, 1982. This signifies that the front end of the nuclear fuel cycle in Japan, from uranium ore to enrichment, is only a step away from commercialization. On the same day, the pilot plant of uranium processing and conversion to UF 6 , the direct purification of uranium ore into uranium hexafluoride, began batch operation at the same works. The construction of the uranium enrichment pilot plant has been advanced in three stages: i.e. OP-1A with 1000 centrifuges, OP-1B with 3000 centrifuges and OP-2 with 3000 centrifuges. With a total of 7000 centrifuges, the pilot plant, the first enrichment plant in Japan, has now a capacity of supplying enriched uranium for six months operation of a 1,000 MW nuclear power plant. (J.P.N.)

  18. Perspectives for the uranium enrichment in Brazil

    International Nuclear Information System (INIS)

    Senna, J.G.S.M.

    1991-01-01

    Through an analysis of the electrical energy future in Brazil, the needs for enriched uranium are discussed, and therefore the importance of developing local capability for self-production. A description of the production processes that are well established is given first, then the analysis itself is performed and finally a visualization of the International Market for enriched uranium is shown. (author)

  19. Enrichment and activation of smectite-poor clay

    Energy Technology Data Exchange (ETDEWEB)

    Sarcevica, Inese; Kostjukovs, Juris; Actint, Andris, E-mail: inese.sarcevicha@gmail.com [Department of Chemistry, University of Latvia, Kr. Valdemara street 48, Riga (Latvia)

    2011-06-23

    A new method of smectite clay enrichment has been developed. The method is based on dispersing clay in a phosphate solution and sequential coagulation. The product of enrichment is characterized with X-ray powder diffraction, wavelength dispersive X-ray fluorescence spectrometry, differential thermal analysis and thermogravimetry. Sorption of methylene blue and hexadecylpyridinium bromide on raw and purified clays was studied.

  20. Nutrient enrichment increases mortality of mangroves.

    Directory of Open Access Journals (Sweden)

    Catherine E Lovelock

    Full Text Available Nutrient enrichment of the coastal zone places intense pressure on marine communities. Previous studies have shown that growth of intertidal mangrove forests is accelerated with enhanced nutrient availability. However, nutrient enrichment favours growth of shoots relative to roots, thus enhancing growth rates but increasing vulnerability to environmental stresses that adversely affect plant water relations. Two such stresses are high salinity and low humidity, both of which require greater investment in roots to meet the demands for water by the shoots. Here we present data from a global network of sites that documents enhanced mortality of mangroves with experimental nutrient enrichment at sites where high sediment salinity was coincident with low rainfall and low humidity. Thus the benefits of increased mangrove growth in response to coastal eutrophication is offset by the costs of decreased resilience due to mortality during drought, with mortality increasing with soil water salinity along climatic gradients.

  1. Environmental enrichment in farm, zoo, companion and experimental animals

    OpenAIRE

    Vučinić Marijana

    2009-01-01

    The paper deals with environmental enrichment for domestic animals at farms, animals in zoos, experimental animals and pet animals. Also, the paper defines and describes different strategies of environmental enrichment. Environmental enrichment is a simple and effective mean of prevention of boredom, behavioral disorders as well as an effective mean of improving animal welfare in farm, zoo, companion and experimental animals. Different items and materials may be used for environmental enrichm...

  2. Method of deuterium isotope separation and enrichment

    International Nuclear Information System (INIS)

    Benson, S.W.

    1978-01-01

    A method of separating deuterium, i.e., heavy hydrogen, from certain naturally occurring sources using tuned infrared lasers to selectively decompose specified classes of organic molecules (i.e., RX) into enriched molecular products containing deuterium atoms is described. The deuterium containing molecules are easily separated from the starting material by absorption, distillation or other simple chemical separation techniques and methods. After evaporation such deuterium containing molecules can be burned to form water with an enriched deuterium content or pyrolyzed to form hydrogen gas with an enriched deuterium content. The undecomposed molecules and the other reaction products which are depleted of their deuterium containing species can be catalytically treated, preferably using normal water, to restore the natural abundance of deuterium and such restored molecules can then be recycled

  3. Application of a method to measure uranium enrichment without use of standards

    International Nuclear Information System (INIS)

    Saule, F.A.; Righetti, M.A.

    1998-01-01

    Full text: The determination of uranium enrichment in the many different stages present at a gaseous diffusion enrichment plant (diffusers, cisterns, deposits in pipes, drums with rests of process), or materials of deposit (plates of fuel elements not irradiated and recipients with uranium oxide), that have several geometries and physics properties of the containers, is very important for safeguards inspections. In this work is tested a non destructive analysis technique to determine the value of uranium enrichment of different samples with uranium materials without use of standards, to apply in safeguards inspections. It was used a hyper pure germanium detector with efficiency of 20% to obtain the gamma spectrum of the samples. In each spectrum, were used the net area values corresponding to four lines of U-235 (at 143, 163, 186 and 205 keV) and three lines of U-238 (258, 766 and 1001 keV); these values were analysed with two different methods. The comparison of the calculated and declared values showed a discrepancy of about 10%. (author) [es

  4. Plasmons in strong superconductors

    International Nuclear Information System (INIS)

    Baldo, M.; Ducoin, C.

    2011-01-01

    We present a study of the possible plasmon excitations that can occur in systems where strong superconductivity is present. In these systems the plasmon energy is comparable to or smaller than the pairing gap. As a prototype of these systems we consider the proton component of Neutron Star matter just below the crust when electron screening is not taken into account. For the realistic case we consider in detail the different aspects of the elementary excitations when the proton, electron components are considered within the Random-Phase Approximation generalized to the superfluid case, while the influence of the neutron component is considered only at qualitative level. Electron screening plays a major role in modifying the proton spectrum and spectral function. At the same time the electron plasmon is strongly modified and damped by the indirect coupling with the superfluid proton component, even at moderately low values of the gap. The excitation spectrum shows the interplay of the different components and their relevance for each excitation modes. The results are relevant for neutrino physics and thermodynamical processes in neutron stars. If electron screening is neglected, the spectral properties of the proton component show some resemblance with the physical situation in high-T c superconductors, and we briefly discuss similarities and differences in this connection. In a general prospect, the results of the study emphasize the role of Coulomb interaction in strong superconductors.

  5. The effect of taurine and enriched environment on behaviour, memory and hippocampus of diabetic rats.

    Science.gov (United States)

    Rahmeier, Francine Luciano; Zavalhia, Lisiane Silveira; Tortorelli, Lucas Silva; Huf, Fernanda; Géa, Luiza Paul; Meurer, Rosalva Thereza; Machado, Aryadne Cardoso; Gomez, Rosane; Fernandes, Marilda da Cruz

    2016-09-06

    Diabetes mellitus (DM) has been studied recently as a major cause of cognitive deficits, memory and neurodegenerative damage. Taurine and enriched environment have stood out for presenting neuroprotective and stimulating effects that deserve further study. In this paper, we examined the effects of taurine and enriched environment in the context of diabetes, evaluating effects on behaviour, memory, death and cellular activity. Eighty-eight Wistar rats were divided into 2 groups (E=enriched environment; C=standard housing). Some animals (24/group) underwent induction of diabetes, and within each group, some animals (half of diabetics (D) and half of non-diabetics (ND)/group) were treated for 30days with taurine (T). Untreated animals received saline (S). In total, there were eight subgroups: DTC, DSC, NDTC, NDSC, DTE, DSE, NDTE and NDSE. During the experiment, short-term memory was evaluated. After 30th day of experiment, the animals were euthanized and was made removal of brains used to immunohistochemistry procedures for GFAP and cleaved caspase-3. As a result, we observed that animals treated with taurine showed better performance in behavioural and memory tasks, and the enriched environment had positive effects, especially in non-diabetic animals. Furthermore, taurine and enriched environment seemed to be able to interfere with neuronal apoptosis and loss of glial cells, and in some instances, these two factors seemed to have synergistic effects. From these data, taurine and enriched environment may have important neurostimulant and neuroprotective effects. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  6. Enriched Housing Reduces Disease Susceptibility to Co-Infection with Porcine Reproductive and Respiratory Virus (PRRSV and Actinobacillus pleuropneumoniae (A. pleuropneumoniae in Young Pigs.

    Directory of Open Access Journals (Sweden)

    Ingrid D E van Dixhoorn

    Full Text Available Until today, anti-microbial drugs have been the therapy of choice to combat bacterial diseases. Resistance against antibiotics is of growing concern in man and animals. Stress, caused by demanding environmental conditions, can reduce immune protection in the host, influencing the onset and outcome of infectious diseases. Therefore psychoneuro-immunological intervention may prove to be a successful approach to diminish the impact of diseases and antibiotics use. This study was designed to investigate the effect of social and environmental enrichment on the impact of disease, referred to as "disease susceptibility", in pigs using a co-infection model of PRRSV and A. pleuropneumoniae. Twenty-eight pigs were raised in four pens under barren conditions and twenty-eight other pigs were raised in four pens under enriched conditions. In the enriched pens a combination of established social and environmental enrichment factors were introduced. Two pens of the barren (BH and two pens of the enriched housed (EH pigs were infected with PRRSV followed by A. pleuropneumoniae, the other two pens in each housing treatment served as control groups. We tested if differences in disease susceptibility in terms of pathological and clinical outcome were related to the different housing regimes and if this was reflected in differences in behavioural and immunological states of the animals. Enriched housed pigs showed a faster clearance of viral PRRSV RNA in blood serum (p = 0.014 and histologically 2.8 fold less interstitial pneumonia signs in the lungs (p = 0.014. More barren housed than enriched housed pigs developed lesions in the lungs (OR = 19.2, p = 0.048 and the lesions in the barren housed pigs showed a higher total pathologic tissue damage score (p<0.001 than those in enriched housed pigs. EH pigs showed less stress-related behaviour and differed immunologically and clinically from BH pigs. We conclude that enriched housing management reduces disease

  7. Capability of the electromagnetic isotope-enrichment facility at ORNL

    International Nuclear Information System (INIS)

    Newman, E.

    1982-01-01

    The isotope separation program at Oak Ridge National Laboratory (ORNL) prepares and distributes electromagnetically enriched stable isotopes to the worldwide scientific community. Among the topics discussed in the present paper are the methods of enriching isotopes, the limitations that apply to the quantity and final assay of the separation products, and a generalized production flowsheet indicating the capability of the facility. A brief description of each of the production steps, from the selection and preparation of initial feedstock to the recovery and distribution of the isotopically enriched material, is presented. The future of the facility, the continued supply of enriched isotopes, and the response of the program to new and changing requirements are emphasized

  8. Atomics international fuel fabrication facility and low enrichment program [contributed by H.W. Hassel, NUKEM

    International Nuclear Information System (INIS)

    Hassel, H.W.

    1993-01-01

    NUKEM handles around almost two tons of highly enriched uranium a year and it was necessary to satisfy all the new physical protection philosophies. That means that we have to install storage and safe fabrication sites for a lot of money, 25 meter thick concrete walls, and different alarm systems. So just to demonstrate how silly this business is, we have just overcome this for highly enriched uranium, and now we speak about low enriched uranium for which we don't need all of these investments to make this business safe. I would-just like to concentrate my words on the status of fabrication and considerations in my company concerning the medium enriched uranium and low enriched uranium. In the table are the different fuel types (see column) and then we have the fabrication in column 2 the experience of my comp any in kg. In column 3 is the irradiation experience of these fuels types. Column 4 shows the studies and calculations made in our company for lower and medium enriched fuels. The preliminary fabrication tests and calculations are in column 5, and in column 6 we have the delivery time for a prototype core in months after UF 6 supply. Column 7 shows the time for the development of specifications including irradiation time in years for 6 and 7 and column is the estimated cost of 6 and 7 There is just one fuel that is not in this summary and that is U-Zr. We now see how complex and sophisticated this business is. I have told you already that we have installed for a lot of millions of Deutsche Mark the physical protection, storage vaults and things like that. Now we have to investigate all these different types of fuels for, as you see, a lot of money. Maybe these are a lot of optimistic figures; anyway the question is, does this make all the overall nuclear situation worldwide easier or not. One cannot answer for the moment, but anyway we have a lot of problems

  9. Use of enriched uranium in Canada's power reactors

    International Nuclear Information System (INIS)

    Dormuth, K.W.; Jackson, D.P.

    2011-01-01

    Recent trends in Canadian nuclear power reactor design and proposed development of nuclear power in Canada have indicated the possibility that Canada will break with its tradition of natural uranium fuelled systems, designed for superior neutron economy and, hence, superior uranium utilization. For instance, the Darlington B new reactor project procurement process included three reactor designs, all employing enriched fuel, although a natural uranium reactor design was included at a late stage in the ensuing environmental assessment for the project as an alternative technology. An evaluation of the alternative designs should include an assessment of the environmental implications through the entire fuel cycle, which unfortunately is not required by the environmental assessment process. Examples of comparative environmental implications of the reactor designs throughout the fuel cycle indicate the importance of these considerations when making a design selection. As Canada does not have enrichment capability, a move toward the use of enriched fuel would mean that Canada would be exporting natural uranium and buying back enriched uranium with value added. From a waste management perspective, Canada would need to deal with mill, refinery, and conversion tailings, as well as with the used fuel from its own reactors, while the enrichment supplier would retain depleted uranium with some commercial value. On the basis of reasoned estimates based on publicly available information, it is expected that enrichment in Canada is likely to be more profitable than exporting natural uranium and buying back enriched uranium. Further, on the basis of environmental assessments for enrichment facilities in other countries, it is expected that an environmental assessment of a properly sited enrichment facility would result in approval. (author)

  10. Georges Besse 2. A new era for enrichment

    International Nuclear Information System (INIS)

    2009-01-01

    Since 1978, AREVA group subsidiary EURODIF's Georges Besse plant has been using gaseous diffusion to enrich uranium and meet the requirements of electricity utilities. Georges Besse II plant, which will use far less electricity, will replace George Besse not so long. The Georges Besse II plant is located on the Tricastin nuclear site in southern France. AREVA ensure delivery of uranium enrichment services in accordance with customer expectations. AREVA obtained the right to use URENCO's centrifugation technology on July 3, 2006. This is the process to be used at Georges Besse II. The new uranium enrichment plant will comprise two enrichment units, with a total production capacity of 7.5 million separative work units, which can be extended to 11 million if needed. Each enrichment unit will include: a Centrifuge Assembly Building (CAB), a Centrifuge Utility Building (CUB) with offices and control room, annexes for purification, supply and extraction of uranium hexafluoride (UF 6 ), modules containing the halls that house the centrifuge cascades. The modular design of the Georges Besse II plant will allow production in the first cascade where as the others cascades are build. The first cascade should be operational in the first half of 2009. At an overall cost of 3 billion euros, this project is one of the largest investments of the decade in France On November 24, 2003, AREVA and URENCO signed an agreement under which AREVA would buy 50% of the shares in the Enrichment Technology Company (ETC), which designs and manufactures centrifuges

  11. Gasket for uranium enrichment plant

    Energy Technology Data Exchange (ETDEWEB)

    Kishi, S; Aiyoshi, H

    1977-02-08

    A gasket to be inserted between flange joints in the equipments and pipe lines of an uranium enrichment plant having neither permeability nor adsorptivity to water while maintaining mechanical, physical and chemical properties of an elastomer gasket is described. A gasket made of an elastomeric material such as a polymer is integratedly formed at its surface with anti-slip projections. The gasket is further surrounded at its upper and lower peripheral sides, as well as outer circumferential portion with a U-sectioned cover (enclosure) made of fluoro-plastics. In this arrangement, the gasket main body shows a gas-tightness for uranium hexafluoride gas and the cover exhibits a gas-tightness for other component gases such as moisture to thereby prevent degradation of the gasket due to absorption and permeation of the moisture.

  12. Metallurgical and reactor physics aspects of using low enrichment fuel in Safari-I

    International Nuclear Information System (INIS)

    1978-09-01

    The feasibility of using lower than 93% enriched fuel in the SAFARI-I research and materials testing reactor is reviewed. Metallurgical experiments show that, using standard U-Al alloy technology and keeping the 235 U loading per element constant without altering the fuel plate thickness, a maximum of 35 weight percent of uranium in the meat can be achieved. This corresponds to using a minimum enrichment of 40% 235 U in order to retain the same mass of 235 U in the core. Even then a loss of approximately 3,3% in reactivity is calculated, which is more than the 2,8% sup(deltak)/k which is normally allowed for burnup. Using current U-Al alloy fuel technology, and an enrichment of approximately 45% 235 U, no changes in core configuration or coolant requirements will be necessary. The use of 20% enriched uranium will require the development of a new fuel design and technology if drastic redesign and modification of the reactor and coolant circuits is to be avoided. Without such new technology, the redesign and modification of the reactor will cost upwards of 3 million dollars and take up to 5 years to complete, requiring a complete shutdown of the reactor for approximately 2 years

  13. Material control and accounting requirements for uranium enrichment facilities

    International Nuclear Information System (INIS)

    Ting, P.

    1991-01-01

    This paper reports that the U.S. Nuclear Regulatory Commission has defined material control and accounting (MC and A) requirement for low-enriched uranium enrichment plants licensed under 10 CFR parts 40 and 70. Following detailed assessment of potential safeguards issues relevant to these facilities, a new MC and A rule was developed. The primary safeguards considerations are detection of the loss of special nuclear material, detection of clandestine production of special nuclear material of low strategic significance for unauthorized use or distribution, and detection of unauthorized production of uranium enriched to ≥10 wt % U-235. The primary safeguards concerns identified were the large absolute limit of error associated with the material balance closing, the inability to shutdown some uranium enrichment technologies to perform a cleanout inventory of the process system, and the flexibility of some of these technologies to produce higher enrichments. Unauthorized production scenarios were identified for some technologies that could circumvent the detection of the production and removal of 5 kilograms of U-235 as high-enriched uranium through conventional material control and accounting programs. Safeguards techniques, including the use of production and process control information, measurements, and technical surveillance, were identified to compensate for these concerns

  14. Development of empirical relation for isotope of uranium in enriched uranium matrix

    International Nuclear Information System (INIS)

    Srivastava, S.K.; Vidyasagar, D.; Jha, S.K.; Tripathi, R.M.

    2018-01-01

    Uranium enriched in 235 U is required in commercial light water reactors to produce a controlled nuclear reaction. Enrichment allows the 235 U isotopes to be increased from 0.71% to a range between 2% to 5% depending upon requirement. The enriched uranium in the form of sintered UO 2 pellet is used for any commercially operating boiling light water reactors. The enriched uranium fuel bundle surface swipes sample is being analysed to assess the tramp uranium as a quality control parameter. It is known that the 234 U isotope also enriched along with 235 U isotope in conventional gaseous diffusion enrichment process. The information about enrichment percentage of 234 U helps to characterize isotopic properties of enriched uranium. A few reports provide the empirical equation and graphs for finding out the specific activity, activity percentage, activity ratio of 234 U isotopes for enriched uranium. Most of them have not provided the reference for the data used and their source. An attempt has been made to model the relationship between 234 U and 235 U as a function of uranium enrichment at low level

  15. Enrichment situation outside the United States

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    Different enrichment technologies are briefly characterized which include gaseous diffusion, which is presently the production mainstay of the United States and France; the gaseous centrifuge which is the production plant for Urenco and the technology for future United States enrichment expansion; the aero-dynamic processes which include the jet nozzle (also known as the Becker process) and the fixed-wall centrifuge (also known as the Helikon process); chemical processes; laser isotope separation processes (also referred to in the literature as LIS); and plasma technology

  16. Characterization of genomic sequence showing strong association with polyembryony among diverse Citrus species and cultivars, and its synteny with Vitis and Populus.

    Science.gov (United States)

    Nakano, Michiharu; Shimada, Takehiko; Endo, Tomoko; Fujii, Hiroshi; Nesumi, Hirohisa; Kita, Masayuki; Ebina, Masumi; Shimizu, Tokurou; Omura, Mitsuo

    2012-02-01

    Polyembryony, in which multiple somatic nucellar cell-derived embryos develop in addition to the zygotic embryo in a seed, is common in the genus Citrus. Previous genetic studies indicated polyembryony is mainly determined by a single locus, but the underlying molecular mechanism is still unclear. As a step towards identification and characterization of the gene or genes responsible for nucellar embryogenesis in Citrus, haplotype-specific physical maps around the polyembryony locus were constructed. By sequencing three BAC clones aligned on the polyembryony haplotype, a single contiguous draft sequence consisting of 380 kb containing 70 predicted open reading frames (ORFs) was reconstructed. Single nucleotide polymorphism genotypes detected in the sequenced genomic region showed strong association with embryo type in Citrus, indicating a common polyembryony locus is shared among widely diverse Citrus cultivars and species. The arrangement of the predicted ORFs in the characterized genomic region showed high collinearity to the genomic sequence of chromosome 4 of Vitis vinifera and linkage group VI of Populus trichocarpa, suggesting that the syntenic relationship among these species is conserved even though V. vinifera and P. trichocarpa are non-apomictic species. This is the first study to characterize in detail the genomic structure of an apomixis locus determining adventitious embryony. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  17. Experimental critical parameters of enriched uranium solution in annular tank geometries

    International Nuclear Information System (INIS)

    Rothe, R.E.

    1996-04-01

    A total of 61 critical configurations are reported for experiments involving various combinations of annular tanks into which enriched uranium solution was pumped. These experiments were performed at two widely separated times in the 1980s under two programs at the Rocky Flats Plant's Critical Mass Laboratory. The uranyl nitrate solution contained about 370 g of uranium per liter, but this concentration varied a little over the duration of the studies. The uranium was enriched to about 93% [sup 235]U. All tanks were typical of sizes commonly found in nuclear production plants. They were about 2 m tall and ranged in diameter from 0.6 m to 1.5 m. Annular thicknesses and conditions of neutron reflection, moderation, and absorption were such that criticality would be achieved with these dimensions. Only 13 of the entire set of 74 experiments proved to be subcritical when tanks were completely filled with solution. Single tanks of several radial thicknesses were studied as well as small line arrays (1 x 2 and 1 x 3) of annular tanks. Many systems were reflected on four sides and the bottom by concrete, but none were reflected from above. Many experiments also contained materials within and outside the annular regions that contained strong neutron absorbers. One program had such a thick external moderator/absorber combination that no reflector was used at all

  18. Experimental critical parameters of enriched uranium solution in annular tank geometries

    Energy Technology Data Exchange (ETDEWEB)

    Rothe, R.E.

    1996-04-01

    A total of 61 critical configurations are reported for experiments involving various combinations of annular tanks into which enriched uranium solution was pumped. These experiments were performed at two widely separated times in the 1980s under two programs at the Rocky Flats Plant`s Critical Mass Laboratory. The uranyl nitrate solution contained about 370 g of uranium per liter, but this concentration varied a little over the duration of the studies. The uranium was enriched to about 93% [sup 235]U. All tanks were typical of sizes commonly found in nuclear production plants. They were about 2 m tall and ranged in diameter from 0.6 m to 1.5 m. Annular thicknesses and conditions of neutron reflection, moderation, and absorption were such that criticality would be achieved with these dimensions. Only 13 of the entire set of 74 experiments proved to be subcritical when tanks were completely filled with solution. Single tanks of several radial thicknesses were studied as well as small line arrays (1 x 2 and 1 x 3) of annular tanks. Many systems were reflected on four sides and the bottom by concrete, but none were reflected from above. Many experiments also contained materials within and outside the annular regions that contained strong neutron absorbers. One program had such a thick external moderator/absorber combination that no reflector was used at all.

  19. Highly Selective Enrichment of Glycopeptides Based on Zwitterionically Functionalized Soluble Nanopolymers

    Science.gov (United States)

    Cao, Weiqian; Huang, Jiangming; Jiang, Biyun; Gao, Xing; Yang, Pengyuan

    2016-07-01

    Efficient glycopeptides enrichment prior to mass spectrometry analysis is essential for glycoproteome study. ZIC-HILIC (zwitterionic hydrophilic interaction liquid chromatography) based glycopeptides enrichment approaches have been attracting more attention for several benefits like easy operating, high enrichment specificity and intact glycopeptide retained. In this study, Poly (amidoamine) dendrimer (PAMAM) was adopted for the synthesis of zwitterionically functionalized (ZICF) materials for glycopeptide enrichment. The multiple branched structure and good solubility of ZICF-PAMAM enables a sufficient interaction with glycopeptides. The ZICF-PAMAM combined with the FASP-mode enrichment strategy exhibits more superior performance compared with the existing methods. It has the minimum detectable concentration of femtomolar level and high recovery rate of over 90.01%, and can efficiently enrich glycopeptides from complex biological samples even for merely 0.1 μL human serum. The remarkable glycopeptides enrichment capacity of ZICF-PAMAM highlights the potential application in in-depth glycoproteome research, which may open up new opportunities for the development of glycoproteomics.

  20. Buckwheat-enriched wheat bread: National market placement possibilities

    Directory of Open Access Journals (Sweden)

    Sakač Marijana B.

    2015-01-01

    Full Text Available Quality parameters and the possibility of successful placement of buckwheat-enriched wheat bread on the national market are presented in this paper. Analysis of the market position of buckwheat-enriched wheat bread includes demands, offer and competition. Elements that affect the overall retail price of buckwheat-enriched wheat bread are given in details, along with SWOT analysis and marketing plan including target market, market supply and product marketing mix. According to all performed analyses it could be concluded that this product should be positioned on the national market, especially for people with special needs and requirements.