WorldWideScience

Sample records for shortest period non-interacting

  1. Finding shortest non-trivial cycles in directed graphs on surfaces

    Directory of Open Access Journals (Sweden)

    Sergio Cabello

    2016-04-01

    Full Text Available Let $D$ be a weighted directed graph cellularly embedded in a surface of genus $g$, orientable or not, possibly with boundary.  We describe algorithms to compute shortest non-contractible and shortest surface non-separating cycles in $D$, generalizing previous results that dealt with undirected graphs.Our first algorithm computes such cycles in $O(n^2\\log n$ time, where $n$ is the total number of vertices and edges of $D$, thus matching the complexity of the best general algorithm in the undirected case.  It revisits and extends Thomassen's 3-path condition; the technique applies to other families of cycles as well.We also provide more efficient algorithms in special cases, such as graphs with small genus or bounded treewidth, using a divide-and-conquer technique that simplifies the graph while preserving the topological properties of its cycles.  Finally, we give an efficient output-sensitive algorithm, whose running time depends on the length of the shortest non-contractible or non-separating cycle.

  2. Small flow rate can supply inwardly migrating shortest-period planets

    Directory of Open Access Journals (Sweden)

    Taylor S.F.

    2013-04-01

    Full Text Available The number of exoplanets found with periods as short as one day and less was surprising given how fast these planets had been expected to migrate into the star due to the tides raised on the star by planets at such close distances. It has been seen as improbable that we would find planets in such a small final fraction of their lives [1]. The favored solution has been that the tidal dissipation is much weaker than expected, which would mean that the final infall would be a larger fraction of the planets’ life. We find no reason, however, to exclude the explanation that a small number of planets are continuously sent migrating inwards such that these planets indeed are in the last fraction of their lives. Following the observation that the distribution of medium planets disfavors tidal dissipation being significantly weaker than has been found from observations of binary stars [2], we now show that the numbers of planets in such a “flow” of excess planets migrating inwards is low enough that even depletion of the three-day pileup is a plausible source. Then the shortest period occurrence distribution would be shaped by planets continuously being sent into the star, which may explain the depletion of the pileup in the Kepler field relative to the solar neighborhood [3]. Because Kepler observes above the galactic plan, [3] suggested the Kepler field may include an older population of stars. The tidal dissipation strength in stars due to giant planets may be not greatly weaker than it is in binary stars.

  3. Shortest Paths and Vehicle Routing

    DEFF Research Database (Denmark)

    Petersen, Bjørn

    This thesis presents how to parallelize a shortest path labeling algorithm. It is shown how to handle Chvátal-Gomory rank-1 cuts in a column generation context. A Branch-and-Cut algorithm is given for the Elementary Shortest Paths Problem with Capacity Constraint. A reformulation of the Vehicle...... Routing Problem based on partial paths is presented. Finally, a practical application of finding shortest paths in the telecommunication industry is shown....

  4. Finding the K shortest hyperpaths using reoptimization

    DEFF Research Database (Denmark)

    Nielsen, Lars Relund; Pretolani, Daniele; Andersen, Kim Allan

    2006-01-01

    The shortest hyperpath problem is an extension of the classical shortest path problem and has applications in many different areas. Recently, algorithms for finding the K shortest hyperpaths in a directed hypergraph have been developed by Andersen, Nielsen and Pretolani. In this paper we improve...... the worst-case computational complexity of an algorithm for finding the K shortest hyperpaths in an acyclic hypergraph. This result is obtained by applying new reoptimization techniques for shortest hyperpaths. The algorithm turns out to be quite effective in practice and has already been successfully...

  5. Special cases of the quadratic shortest path problem

    NARCIS (Netherlands)

    Sotirov, Renata; Hu, Hao

    2017-01-01

    The quadratic shortest path problem (QSPP) is the problem of finding a path with prespecified start vertex s and end vertex t in a digraph such that the sum of weights of arcs and the sum of interaction costs over all pairs of arcs on the path is minimized. We first consider a variant of the QSPP

  6. SPTH3: subroutine for finding shortest sabotage paths

    International Nuclear Information System (INIS)

    Hulme, B.L.; Holdridge, D.B.

    1977-07-01

    This document explains how to construct a sabotage graph which models any fixed-site facility and how to use the subroutine SPTH3 to find shortest paths in the graph. The shortest sabotage paths represent physical routes through the site which would allow an adversary to take advantage of the greatest weaknesses in the system of barriers and alarms. The subroutine SPTH3 is a tool with which safeguards designers and analysts can study the relative effects of design changes on the adversary routing problem. In addition to showing how to use SPTH3, this report discusses the methods used to find shortest paths and several implementation details which cause SPTH3 to be extremely efficient

  7. ESHOPPS: A COMPUTATIONAL TOOL TO AID THE TEACHING OF SHORTEST PATH ALGORITHMS

    Directory of Open Access Journals (Sweden)

    S. J. de A. LIMA

    2015-07-01

    Full Text Available The development of a computational tool called EShoPPS – Environment for Shortest Path Problem Solving, which is used to assist students in understanding the working of Dijkstra, Greedy search and A*(star algorithms is presented in this paper. Such algorithms are commonly taught in graduate and undergraduate courses of Engineering and Informatics and are used for solving many optimization problems that can be characterized as Shortest Path Problem. The EShoPPS is an interactive tool that allows students to create a graph representing the problem and also helps in developing their knowledge of each specific algorithm. Experiments performed with 155 students of undergraduate and graduate courses such as Industrial Engineering, Computer Science and Information Systems have shown that by using the EShoPPS tool students were able to improve their interpretation of investigated algorithms.

  8. A NEW APPROACH ON SHORTEST PATH IN FUZZY ENVIRONMENT

    OpenAIRE

    A. Nagoorgani; A. Mumtaj Begam

    2010-01-01

    This paper introduces a new type of fuzzy shortest path network problem using triangular fuzzy number. To find the smallest edge by the fuzzy distance using graded mean integration representation of generalized fuzzy number for every node. Thus the optimum shortest path for the given problem is obtained.

  9. Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.

    Directory of Open Access Journals (Sweden)

    J R Managbanag

    Full Text Available BACKGROUND: Identification of genes that modulate longevity is a major focus of aging-related research and an area of intense public interest. In addition to facilitating an improved understanding of the basic mechanisms of aging, such genes represent potential targets for therapeutic intervention in multiple age-associated diseases, including cancer, heart disease, diabetes, and neurodegenerative disorders. To date, however, targeted efforts at identifying longevity-associated genes have been limited by a lack of predictive power, and useful algorithms for candidate gene-identification have also been lacking. METHODOLOGY/PRINCIPAL FINDINGS: We have utilized a shortest-path network analysis to identify novel genes that modulate longevity in Saccharomyces cerevisiae. Based on a set of previously reported genes associated with increased life span, we applied a shortest-path network algorithm to a pre-existing protein-protein interaction dataset in order to construct a shortest-path longevity network. To validate this network, the replicative aging potential of 88 single-gene deletion strains corresponding to predicted components of the shortest-path longevity network was determined. Here we report that the single-gene deletion strains identified by our shortest-path longevity analysis are significantly enriched for mutations conferring either increased or decreased replicative life span, relative to a randomly selected set of 564 single-gene deletion strains or to the current data set available for the entire haploid deletion collection. Further, we report the identification of previously unknown longevity genes, several of which function in a conserved longevity pathway believed to mediate life span extension in response to dietary restriction. CONCLUSIONS/SIGNIFICANCE: This work demonstrates that shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity and represents the first application of

  10. An asymmetric shortest queue problem

    NARCIS (Netherlands)

    Adan, I.J.B.F.; Wessels, J.; Zijm, W.H.M.

    1989-01-01

    In this paper we study a system consisting of two identical servers, each with exponentially distributed service times. Jobs arrive according to a Poisson stream. On arrival a job joins the shortest queue and in case both queues have equal length. he joins queue 1 say with probability q and queue 2

  11. The Shortest QRS Duration of an Electrocardiogram Might Be an Optimal Electrocardiographic Predictor for Response to Cardiac Resynchronization Therapy.

    Science.gov (United States)

    Chen, Jan-Yow; Lin, Kuo-Hung; Chang, Kuan-Cheng; Chou, Che-Yi

    2017-08-03

    QRS duration has been associated with the response to cardiac resynchronization therapy (CRT). However, the methods for defining QRS duration to predict the outcome of CRT have discrepancies in previous reports. The aim of this study was to determine an optimal measurement of QRS duration to predict the response to CRT.Sixty-one patients who received CRT were analyzed. All patients had class III-IV heart failure, left ventricular ejection fraction not more than 35%, and complete left bundle branch block. The shortest, longest, and average QRS durations from the 12 leads of each electrocardiogram (ECG) were measured. The responses to CRT were determined using the changes in echocardiography after 6 months. Thirty-five (57.4%) patients were responders and 26 (42.6%) patients were non-responders. The pre-procedure shortest, average, and longest QRS durations and the QRS shortening (ΔQRS) of the shortest QRS duration were significantly associated with the response to CRT in a univariate logistic regression analysis (P = 0.002, P = 0.03, P = 0.04 and P = 0.04, respectively). Based on the measurement of the area under curve of the receiver operating characteristic curve, only the pre-procedure shortest QRS duration and the ΔQRS of the shortest QRS duration showed significant discrimination for the response to CRT (P = 0.002 and P = 0.038, respectively). Multivariable logistic regression showed the pre-procedure shortest QRS duration is an independent predictor for the response to CRT.The shortest QRS duration from the 12 leads of the electrocardiogram might be an optimal measurement to predict the response to CRT.

  12. Interacting binaries

    International Nuclear Information System (INIS)

    Eggleton, P.P.; Pringle, J.E.

    1985-01-01

    This volume contains 15 review articles in the field of binary stars. The subjects reviewed span considerably, from the shortest period of interacting binaries to the longest, symbiotic stars. Also included are articles on Algols, X-ray binaries and Wolf-Rayet stars (single and binary). Contents: Preface. List of Participants. Activity of Contact Binary Systems. Wolf-Rayet Stars and Binarity. Symbiotic Stars. Massive X-ray Binaries. Stars that go Hump in the Night: The SU UMa Stars. Interacting Binaries - Summing Up

  13. Algorithm for shortest path search in Geographic Information Systems by using reduced graphs.

    Science.gov (United States)

    Rodríguez-Puente, Rafael; Lazo-Cortés, Manuel S

    2013-01-01

    The use of Geographic Information Systems has increased considerably since the eighties and nineties. As one of their most demanding applications we can mention shortest paths search. Several studies about shortest path search show the feasibility of using graphs for this purpose. Dijkstra's algorithm is one of the classic shortest path search algorithms. This algorithm is not well suited for shortest path search in large graphs. This is the reason why various modifications to Dijkstra's algorithm have been proposed by several authors using heuristics to reduce the run time of shortest path search. One of the most used heuristic algorithms is the A* algorithm, the main goal is to reduce the run time by reducing the search space. This article proposes a modification of Dijkstra's shortest path search algorithm in reduced graphs. It shows that the cost of the path found in this work, is equal to the cost of the path found using Dijkstra's algorithm in the original graph. The results of finding the shortest path, applying the proposed algorithm, Dijkstra's algorithm and A* algorithm, are compared. This comparison shows that, by applying the approach proposed, it is possible to obtain the optimal path in a similar or even in less time than when using heuristic algorithms.

  14. Matrix-geometric analysis of the shortest queue problem with threshold jockeying

    NARCIS (Netherlands)

    Zijm, Willem H.M.; Adan, I.J.B.F.; Wessels, J.

    1993-01-01

    In this paper we study a system consisting of c parallel servers with possibly different service rates. Jobs arrive according to a Poisson stream and generate an exponentially distributed workload. An arriving job joins the shortest queue, where in case of multiple shortest queues, one of these

  15. Analysis of the shortest queue problem

    NARCIS (Netherlands)

    Adan, I.J.B.F.; Wessels, J.; Zijm, W.H.M.

    1989-01-01

    In this paper we study a system consisting of two identical servers, each with exponentially distributed service times. Jobs arrive according to a Poisson stream. On arrival a job joins the shortest queue and in case both queues have equal length, he joins either queue with probability ½. We show

  16. Euclidean shortest paths exact or approximate algorithms

    CERN Document Server

    Li, Fajie

    2014-01-01

    This book reviews algorithms for the exact or approximate solution of shortest-path problems, with a specific focus on a class of algorithms called rubberband algorithms. The coverage includes mathematical proofs for many of the given statements.

  17. The shortest-path problem analysis and comparison of methods

    CERN Document Server

    Ortega-Arranz, Hector; Gonzalez-Escribano, Arturo

    2014-01-01

    Many applications in different domains need to calculate the shortest-path between two points in a graph. In this paper we describe this shortest path problem in detail, starting with the classic Dijkstra's algorithm and moving to more advanced solutions that are currently applied to road network routing, including the use of heuristics and precomputation techniques. Since several of these improvements involve subtle changes to the search space, it may be difficult to appreciate their benefits in terms of time or space requirements. To make methods more comprehensive and to facilitate their co

  18. Ranking shortest paths in Stochastic time-denpendent networks

    DEFF Research Database (Denmark)

    Nielsen, Lars Relund; Andersen, Kim Allan; Pretolani, Daniele

    A substantial amount of research has been devoted to the shortest path problem in networks where travel times are stochastic or (deterministic and) time-dependent. More recently, a growing interest has been attracted by networks that are both stochastic and time-dependent. In these networks, the ...... present a computational comparison of time-adaptive and a priori route choices, pointing out the effect of travel time and cost distributions. The reported results show that, under realistic distributions, our solution methods are effective.......A substantial amount of research has been devoted to the shortest path problem in networks where travel times are stochastic or (deterministic and) time-dependent. More recently, a growing interest has been attracted by networks that are both stochastic and time-dependent. In these networks...

  19. K shortest paths in stochastic time-dependent networks

    DEFF Research Database (Denmark)

    Nielsen, Lars Relund; Pretolani, Daniele; Andersen, Kim Allan

    2004-01-01

    A substantial amount of research has been devoted to the shortest path problem in networks where travel times are stochastic or (deterministic and) time-dependent. More recently, a growing interest has been attracted by networks that are both stochastic and time-dependent. In these networks, the ...... present a computational comparison of time-adaptive and a priori route choices, pointing out the effect of travel time and cost distributions. The reported results show that, under realistic distributions, our solution methods are effective.......A substantial amount of research has been devoted to the shortest path problem in networks where travel times are stochastic or (deterministic and) time-dependent. More recently, a growing interest has been attracted by networks that are both stochastic and time-dependent. In these networks...

  20. comparative analysis and implementation of dijkstra's shortest path

    African Journals Online (AJOL)

    user

    path problem requires finding a single shortest-path between given vertices s and t; ... Bridge in 1735, [5 – 10]. This problem led to the .... their advancements from new design paradigms, data structures ..... .

  1. Analysis of the asymmetric shortest queue problem

    NARCIS (Netherlands)

    Adan, I.J.B.F.; Wessels, J.; Zijm, W.H.M.

    1990-01-01

    In this paper we study a system consisting of two parallel servers with different service rates. Jobs arrive according to a Poisson stream and generate an exponentially distributed workload. On arrival a job joins the shortest queue and in case both queues have equal lengths, he joins the first

  2. Analysis of the asymmetric shortest queue problem

    NARCIS (Netherlands)

    Adan, I.J.B.F.; Wessels, J.; Zijm, W. H M

    1991-01-01

    In this paper we study a system consisting of two parallel servers with different service rates. Jobs arrive according to a Poisson stream and generate an exponentially distributed workload. On arrival a job joins the shortest queue and in case both queues have equal lengths, he joins the first

  3. Analysis of the symmetric shortest queue problem

    NARCIS (Netherlands)

    Adan, I.J.B.F.; Wessels, J.; Zijm, W.H.M.

    1990-01-01

    In this paper we study a system consisting of two identical servers, each with exponentially distributed service times. Jobs arrive according to a Poisson stream. On· arrival a job joins the shortest queue and in case both queues have equal lengths, he joins either queue with probability ½. By using

  4. Analysis of the symmetric shortest queue problem

    NARCIS (Netherlands)

    Adan, I.J.B.F.; Wessels, J.; Zijm, W.H.M.

    1990-01-01

    In this paper we study a system consisting of two identical servers, each with exponentially distributed service times. Jobs arrive according to a Poisson stream. On arrival a job joins the shortest queue and in case both queues have equal lengths, he joins either queue with probability 1/2. By

  5. The time-varying shortest path problem with fuzzy transit costs and speedup

    Directory of Open Access Journals (Sweden)

    Rezapour Hassan

    2016-08-01

    Full Text Available In this paper, we focus on the time-varying shortest path problem, where the transit costs are fuzzy numbers. Moreover, we consider this problem in which the transit time can be shortened at a fuzzy speedup cost. Speedup may also be a better decision to find the shortest path from a source vertex to a specified vertex.

  6. Influence of drag force upon the shortest time trajectory of an aircraft

    Directory of Open Access Journals (Sweden)

    Andrei CRAIFALEANU

    2015-06-01

    Full Text Available The shortest time trajectory of an aircraft between two given locations is determined using a simple mathematical model. By taking into account the drag force (viscous friction force with the air, a problem of variational calculus is obtained which consists in determining two functions that minimize a functional, subject to a non-holonomic constraint. The trajectory is determined directly, by numerical integration of Euler equations with multipliers. Three types of drag forces were considered: constant, linear and quadratic. The results are verified through comparison to the values obtained from numerical minimization of the involved functional approximate forms.

  7. Impacts of Different Mobile User Interfaces on Students’ Satisfaction for Learning Dijkstra’s Shortest Path Algorithm

    Directory of Open Access Journals (Sweden)

    Mazyar Seraj

    2014-10-01

    Full Text Available This paper describes an experimental study of learning Dijkstra’s shortest path algorithm on mobile devices. The aim of the study is to investigate and compare the impacts of two different mobile screen user interfaces on students’ satisfaction for learning the technical subject. A mobile learning prototype was developed for learning Dijkstra’s shortest path algorithm on Apple iPhone 4 operated on iPhone operating system (iOS, and Acer Inconia Tab operated on an Android operating system. Thirty students, who are either currently studying or had previously studied Computer Networks, were recruited for the usability trial. At the end of each single session, students’ satisfaction interacting with the two mobile devices was measured using QUIS questionnaire. Although there is no significant difference in students’ satisfaction between the two different mobile screen interfaces, the subjective findings indicate that Acer Inconia Tab gained higher scores as compared to Apple iPhone 4.

  8. Shortest Path Problems in a Stochastic and Dynamic Environment

    National Research Council Canada - National Science Library

    Cho, Jae

    2003-01-01

    .... Particularly, we develop a variety of algorithms to solve the expected shortest path problem in addition to techniques for computing the total travel time distribution along a path in the network...

  9. An Application of Multi-Criteria Shortest Path to a Customizable Hex-Map Environment

    Science.gov (United States)

    2015-03-26

    47 Appendix A. Shortest Path Code ( VBA ) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 Appendix B. Quad Chart...efficient shortest path algorithm into the modeling environment, namely Excel VBA . While various algorithms offer the potential for more efficiency in...graphical interface is extremely intuitive and easily accessible to a user with no prior knowledge of the system. Since the Metz model is based on the

  10. External Memory Algorithms for Diameter and All-Pair Shortest-Paths on Sparse Graphs

    DEFF Research Database (Denmark)

    Arge, Lars; Meyer, Ulrich; Toma, Laura

    2004-01-01

    We present several new external-memory algorithms for finding all-pairs shortest paths in a V -node, Eedge undirected graph. For all-pairs shortest paths and diameter in unweighted undirected graphs we present cache-oblivious algorithms with O(V · E B logM B E B) I/Os, where B is the block-size a...

  11. Finding Shortest Paths on Terrains by Killing Two Birds with One Stone

    DEFF Research Database (Denmark)

    Kaul, Manohar; Wong, Raymond Chi-Wing; Yang, Bin

    2013-01-01

    With the increasing availability of terrain data, e.g., from aerial laser scans, the management of such data is attracting increasing at- tention in both industry and academia. In particular, spatial queries, e.g., k -nearest neighbor and reverse nearest neighbor queries, in Euclidean and spatial...... network spaces are being extended to ter- rains. Such queries all rely on an important operation, that of finding shortest surface distances. However, shortest surface dis- tance computation is very time consuming. We propose techniques that enable efficient computation of lower and upper bounds...... of the shortest surface distance, which enable faster query processing by eliminating expensive distance computations. Empirical studies show that our bounds are much tighter than the best-known bounds in many cases and that they enable speedups of up to 43 times for some well-known spatial querie...

  12. Optimal solution for travelling salesman problem using heuristic shortest path algorithm with imprecise arc length

    Science.gov (United States)

    Bakar, Sumarni Abu; Ibrahim, Milbah

    2017-08-01

    The shortest path problem is a popular problem in graph theory. It is about finding a path with minimum length between a specified pair of vertices. In any network the weight of each edge is usually represented in a form of crisp real number and subsequently the weight is used in the calculation of shortest path problem using deterministic algorithms. However, due to failure, uncertainty is always encountered in practice whereby the weight of edge of the network is uncertain and imprecise. In this paper, a modified algorithm which utilized heuristic shortest path method and fuzzy approach is proposed for solving a network with imprecise arc length. Here, interval number and triangular fuzzy number in representing arc length of the network are considered. The modified algorithm is then applied to a specific example of the Travelling Salesman Problem (TSP). Total shortest distance obtained from this algorithm is then compared with the total distance obtained from traditional nearest neighbour heuristic algorithm. The result shows that the modified algorithm can provide not only on the sequence of visited cities which shown to be similar with traditional approach but it also provides a good measurement of total shortest distance which is lesser as compared to the total shortest distance calculated using traditional approach. Hence, this research could contribute to the enrichment of methods used in solving TSP.

  13. The relationship between partial upper-airway obstruction and inter-breath transition period during sleep.

    Science.gov (United States)

    Mann, Dwayne L; Edwards, Bradley A; Joosten, Simon A; Hamilton, Garun S; Landry, Shane; Sands, Scott A; Wilson, Stephen J; Terrill, Philip I

    2017-10-01

    Short pauses or "transition-periods" at the end of expiration and prior to subsequent inspiration are commonly observed during sleep in humans. However, the role of transition periods in regulating ventilation during physiological challenges such as partial airway obstruction (PAO) has not been investigated. Twenty-nine obstructive sleep apnea patients and eight controls underwent overnight polysomnography with an epiglottic catheter. Sustained-PAO segments (increased epiglottic pressure over ≥5 breaths without increased peak inspiratory flow) and unobstructed reference segments were manually scored during apnea-free non-REM sleep. Nasal pressure data was computationally segmented into inspiratory (T I , shortest period achieving 95% inspiratory volume), expiratory (T E , shortest period achieving 95% expiratory volume), and inter-breath transition period (T Trans , period between T E and subsequent T I ). Compared with reference segments, sustained-PAO segments had a mean relative reduction in T Trans (-24.7±17.6%, P<0.001), elevated T I (11.8±10.5%, P<0.001), and a small reduction in T E (-3.9±8.0, P≤0.05). Compensatory increases in inspiratory period during PAO are primarily explained by reduced transition period and not by reduced expiratory period. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Structural parcellation of the thalamus using shortest-path tractography

    DEFF Research Database (Denmark)

    Kasenburg, Niklas; Darkner, Sune; Hahn, Ute

    2016-01-01

    that parcellation of the thalamus results in p-value maps that are spatially coherent across subjects. Comparing to the state-of-the-art parcellation of Behrens et al. [1], we observe some agreement, but the soft segmentation exhibits better stability for voxels connected to multiple target regions.......We demonstrate how structural parcellation can be implemented using shortest-path tractography, thereby addressing some of the shortcomings of the conventional approaches. In particular, our algorithm quantifies, via p-values, the confidence that a voxel in the parcellated region is connected...... to each cortical target region. Calculation of these statistical measures is derived from a rank-based test on the histogram of tract-based scores from all the shortest paths found between the source voxel and each voxel within the target region. Using data from the Human Connectome Project, we show...

  15. The shortest path algorithm performance comparison in graph and relational database on a transportation network

    Directory of Open Access Journals (Sweden)

    Mario Miler

    2014-02-01

    Full Text Available In the field of geoinformation and transportation science, the shortest path is calculated on graph data mostly found in road and transportation networks. This data is often stored in various database systems. Many applications dealing with transportation network require calculation of the shortest path. The objective of this research is to compare the performance of Dijkstra shortest path calculation in PostgreSQL (with pgRouting and Neo4j graph database for the purpose of determining if there is any difference regarding the speed of the calculation. Benchmarking was done on commodity hardware using OpenStreetMap road network. The first assumption is that Neo4j graph database would be well suited for the shortest path calculation on transportation networks but this does not come without some cost. Memory proved to be an issue in Neo4j setup when dealing with larger transportation networks.

  16. Multiple Object Tracking Using the Shortest Path Faster Association Algorithm

    Directory of Open Access Journals (Sweden)

    Zhenghao Xi

    2014-01-01

    Full Text Available To solve the persistently multiple object tracking in cluttered environments, this paper presents a novel tracking association approach based on the shortest path faster algorithm. First, the multiple object tracking is formulated as an integer programming problem of the flow network. Then we relax the integer programming to a standard linear programming problem. Therefore, the global optimum can be quickly obtained using the shortest path faster algorithm. The proposed method avoids the difficulties of integer programming, and it has a lower worst-case complexity than competing methods but better robustness and tracking accuracy in complex environments. Simulation results show that the proposed algorithm takes less time than other state-of-the-art methods and can operate in real time.

  17. Observations and light curve solutions of four ultrashort-period binaries

    Directory of Open Access Journals (Sweden)

    Kjurkchieva D.

    2016-01-01

    Full Text Available The paper presents light curve solutions of our observations of four new ultrashort-period eclipsing binaries with MS components. Two of them have periods almost at the upper limit (0.22 days of the ultrashort-period binaries, while the periods of around 0.18 days of CSS J171508.5+350658 and CSS J214633.8+120016 are amongst the shortest known orbital periods. CSS J171410.0+ 445850, CSS J214633.8+120016 and CSS J224326.0+154532 are over contact binaries with fill out factors around 0.25 while CSS J171508.5+350658 is a semidetached system. The two targets with shortest periods consist of M dwarfs.

  18. DiversePathsJ: diverse shortest paths for bioimage analysis.

    Science.gov (United States)

    Uhlmann, Virginie; Haubold, Carsten; Hamprecht, Fred A; Unser, Michael

    2018-02-01

    We introduce a formulation for the general task of finding diverse shortest paths between two end-points. Our approach is not linked to a specific biological problem and can be applied to a large variety of images thanks to its generic implementation as a user-friendly ImageJ/Fiji plugin. It relies on the introduction of additional layers in a Viterbi path graph, which requires slight modifications to the standard Viterbi algorithm rules. This layered graph construction allows for the specification of various constraints imposing diversity between solutions. The software allows obtaining a collection of diverse shortest paths under some user-defined constraints through a convenient and user-friendly interface. It can be used alone or be integrated into larger image analysis pipelines. http://bigwww.epfl.ch/algorithms/diversepathsj. michael.unser@epfl.ch or fred.hamprecht@iwr.uni-heidelberg.de. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

  19. Effective caching of shortest paths for location-based services

    DEFF Research Database (Denmark)

    Jensen, Christian S.; Thomsen, Jeppe Rishede; Yiu, Man Lung

    2012-01-01

    Web search is ubiquitous in our daily lives. Caching has been extensively used to reduce the computation time of the search engine and reduce the network traffic beyond a proxy server. Another form of web search, known as online shortest path search, is popular due to advances in geo...

  20. The shortest-known-period star orbiting our Galaxy's supermassive black hole.

    Science.gov (United States)

    Meyer, L; Ghez, A M; Schödel, R; Yelda, S; Boehle, A; Lu, J R; Do, T; Morris, M R; Becklin, E E; Matthews, K

    2012-10-05

    Stars with short orbital periods at the center of our Galaxy offer a powerful probe of a supermassive black hole. Over the past 17 years, the W. M. Keck Observatory has been used to image the galactic center at the highest angular resolution possible today. By adding to this data set and advancing methodologies, we have detected S0-102, a star orbiting our Galaxy's supermassive black hole with a period of just 11.5 years. S0-102 doubles the number of known stars with full phase coverage and periods of less than 20 years. It thereby provides the opportunity, with future measurements, to resolve degeneracies in the parameters describing the central gravitational potential and to test Einstein's theory of general relativity in an unexplored regime.

  1. Do native brown trout and non-native brook trout interact reproductively?

    Science.gov (United States)

    Cucherousset, J.; Aymes, J. C.; Poulet, N.; Santoul, F.; Céréghino, R.

    2008-07-01

    Reproductive interactions between native and non-native species of fish have received little attention compared to other types of interactions such as predation or competition for food and habitat. We studied the reproductive interactions between non-native brook trout ( Salvelinus fontinalis) and native brown trout ( Salmo trutta) in a Pyrenees Mountain stream (SW France). We found evidence of significant interspecific interactions owing to consistent spatial and temporal overlap in redd localizations and spawning periods. We observed mixed spawning groups composed of the two species, interspecific subordinate males, and presence of natural hybrids (tiger trout). These reproductive interactions could be detrimental to the reproduction success of both species. Our study shows that non-native species might have detrimental effects on native species via subtle hybridization behavior.

  2. Prograph Based Analysis of Single Source Shortest Path Problem with Few Distinct Positive Lengths

    Directory of Open Access Journals (Sweden)

    B. Bhowmik

    2011-08-01

    Full Text Available In this paper we propose an experimental study model S3P2 of a fast fully dynamic programming algorithm design technique in finite directed graphs with few distinct nonnegative real edge weights. The Bellman-Ford’s approach for shortest path problems has come out in various implementations. In this paper the approach once again is re-investigated with adjacency matrix selection in associate least running time. The model tests proposed algorithm against arbitrarily but positive valued weighted digraphs introducing notion of Prograph that speeds up finding the shortest path over previous implementations. Our experiments have established abstract results with the intention that the proposed algorithm can consistently dominate other existing algorithms for Single Source Shortest Path Problems. A comparison study is also shown among Dijkstra’s algorithm, Bellman-Ford algorithm, and our algorithm.

  3. The Shortest Path Problems in Battery-Electric Vehicle Dispatching with Battery Renewal

    Directory of Open Access Journals (Sweden)

    Minfang Huang

    2016-06-01

    Full Text Available Electric vehicles play a key role for developing an eco-sustainable transport system. One critical component of an electric vehicle is its battery, which can be quickly charged or exchanged before it runs out. The problem of electric vehicle dispatching falls into the category of the shortest path problem with resource renewal. In this paper, we study the shortest path problems in (1 electric transit bus scheduling and (2 electric truck routing with time windows. In these applications, a fully-charged battery allows running a limited operational distance, and the battery before depletion needs to be quickly charged or exchanged with a fully-charged one at a battery management facility. The limited distance and battery renewal result in a shortest path problem with resource renewal. We develop a label-correcting algorithm with state space relaxation to find optimal solutions. In the computational experiments, real-world road geometry data are used to generate realistic travel distances, and other types of data are obtained from the real world or randomly generated. The computational results show that the label-correcting algorithm performs very well.

  4. Shortest multiple disconnected path for the analysis of entanglements in two- and three-dimensional polymeric systems

    Science.gov (United States)

    Kröger, Martin

    2005-06-01

    We present an algorithm which returns a shortest path and related number of entanglements for a given configuration of a polymeric system in 2 or 3 dimensions. Rubinstein and Helfand, and later Everaers et al. introduced a concept to extract primitive paths for dense polymeric melts made of linear chains (a multiple disconnected multibead 'path'), where each primitive path is defined as a path connecting the (space-fixed) ends of a polymer under the constraint of non-interpenetration (excluded volume) between primitive paths of different chains, such that the multiple disconnected path fulfills a minimization criterion. The present algorithm uses geometrical operations and provides a—model independent—efficient approximate solution to this challenging problem. Primitive paths are treated as 'infinitely' thin (we further allow for finite thickness to model excluded volume), and tensionless lines rather than multibead chains, excluded volume is taken into account without a force law. The present implementation allows to construct a shortest multiple disconnected path (SP) for 2D systems (polymeric chain within spherical obstacles) and an optimal SP for 3D systems (collection of polymeric chains). The number of entanglements is then simply obtained from the SP as either the number of interior kinks, or from the average length of a line segment. Further, information about structure and potentially also the dynamics of entanglements is immediately available from the SP. We apply the method to study the 'concentration' dependence of the degree of entanglement in phantom chain systems. Program summaryTitle of program:Z Catalogue number:ADVG Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADVG Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Computer for which the program is designed and others on which it has been tested: Silicon Graphics (Irix), Sun (Solaris), PC (Linux) Operating systems or monitors under which the

  5. Evaluation of Shortest Paths in Road Network

    Directory of Open Access Journals (Sweden)

    Farrukh Shehzad

    2009-06-01

    Full Text Available Optimization is a key factor in almost all the topics of operations research / management science and economics.The road networks can be optimized within different constraints like time, distance, cost and traffic running onthe roads.This study is based on optimization of real road network by means of distances. Two main objectives arepursued in this research: 1 road distances among different routes are composed in detail; 2 two standardalgorithms (Dijkstra and Floyd-Warshall algoritms are applied to optimize/minimize these distances for bothsingle-source and all-pairs shortest path problems.

  6. Non-equilibrium fluctuation-induced interactions

    International Nuclear Information System (INIS)

    Dean, David S

    2012-01-01

    We discuss non-equilibrium aspects of fluctuation-induced interactions. While the equilibrium behavior of such interactions has been extensively studied and is relatively well understood, the study of these interactions out of equilibrium is relatively new. We discuss recent results on the non-equilibrium behavior of systems whose dynamics is of the dissipative stochastic type and identify a number of outstanding problems concerning non-equilibrium fluctuation-induced interactions.

  7. Spatial interpolation of fine particulate matter concentrations using the shortest wind-field path distance.

    Directory of Open Access Journals (Sweden)

    Longxiang Li

    Full Text Available Effective assessments of air-pollution exposure depend on the ability to accurately predict pollutant concentrations at unmonitored locations, which can be achieved through spatial interpolation. However, most interpolation approaches currently in use are based on the Euclidean distance, which cannot account for the complex nonlinear features displayed by air-pollution distributions in the wind-field. In this study, an interpolation method based on the shortest path distance is developed to characterize the impact of complex urban wind-field on the distribution of the particulate matter concentration. In this method, the wind-field is incorporated by first interpolating the observed wind-field from a meteorological-station network, then using this continuous wind-field to construct a cost surface based on Gaussian dispersion model and calculating the shortest wind-field path distances between locations, and finally replacing the Euclidean distances typically used in Inverse Distance Weighting (IDW with the shortest wind-field path distances. This proposed methodology is used to generate daily and hourly estimation surfaces for the particulate matter concentration in the urban area of Beijing in May 2013. This study demonstrates that wind-fields can be incorporated into an interpolation framework using the shortest wind-field path distance, which leads to a remarkable improvement in both the prediction accuracy and the visual reproduction of the wind-flow effect, both of which are of great importance for the assessment of the effects of pollutants on human health.

  8. Periodic and quasiperiodic revivals in periodically driven interacting quantum systems

    Science.gov (United States)

    Luitz, David J.; Lazarides, Achilleas; Bar Lev, Yevgeny

    2018-01-01

    Recently it has been shown that interparticle interactions generically destroy dynamical localization in periodically driven systems, resulting in diffusive transport and heating. In this Rapid Communication we rigorously construct a family of interacting driven systems which are dynamically localized and effectively decoupled from the external driving potential. We show that these systems exhibit tunable periodic or quasiperiodic revivals of the many-body wave function and thus of all physical observables. By numerically examining spinless fermions on a one-dimensional lattice we show that the analytically obtained revivals of such systems remain stable for finite systems with open boundary conditions while having a finite lifetime in the presence of static spatial disorder. We find this lifetime to be inversely proportional to the disorder strength.

  9. MARKETING DATABASES – THE SHORTEST WAY TO CLIENT’S HEART

    Directory of Open Access Journals (Sweden)

    Popa Adela Laura

    2008-05-01

    Full Text Available The aim of this paper is to present the potential which could be offered by managing databases in direct marketing through gathering the information that could offer the shortest and efficient way to the clients needs. The paper includes the necessary steps to make this activity a real success

  10. Small flow rate can supply inwardly migrating shortest-period planets

    OpenAIRE

    Taylor, Stuart F.

    2013-01-01

    The number of exoplanets found with periods as short as one day and less was surprising given how fast these planets had been expected to migrate into the star due to the tides raised on the star by planets at such close distances. It has been seen as improbable that we would find planets in such a small final fraction of their lives. The favored solution has been that the tidal dissipation is much weaker than expected, which would mean that the final infall would be a larger fraction of the ...

  11. A new approach to shortest paths on networks based on the quantum bosonic mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Jiang Xin; Wang Hailong; Tang Shaoting; Ma Lili; Zhang Zhanli; Zheng Zhiming, E-mail: jiangxin@ss.buaa.edu.cn [Key Laboratory of Mathematics, Informatics and Behavioral Semantics, Ministry of Education, Beijing University of Aeronautics and Astronautics, 100191 Beijing (China)

    2011-01-15

    This paper presents quantum bosonic shortest path searching (QBSPS), a natural, practical and highly heuristic physical algorithm for reasoning about the recognition of network structure via quantum dynamics. QBSPS is based on an Anderson-like itinerant bosonic system in which a boson's Green function is used as a navigation pointer for one to accurately approach the terminals. QBSPS is demonstrated by rigorous mathematical and physical proofs and plenty of simulations, showing how it can be used as a greedy routing to seek the shortest path between different locations. In methodology, it is an interesting and new algorithm rooted in the quantum mechanism other than combinatorics. In practice, for the all-pairs shortest-path problem in a random scale-free network with N vertices, QBSPS runs in O({mu}(N) ln ln N) time. In application, we suggest that the corresponding experimental realizations are feasible by considering path searching in quantum optical communication networks; in this situation, the method performs a pure local search on networks without requiring the global structure that is necessary for current graph algorithms.

  12. Experiments with the auction algorithm for the shortest path problem

    DEFF Research Database (Denmark)

    Larsen, Jesper; Pedersen, Ib

    1999-01-01

    The auction approach for the shortest path problem (SPP) as introduced by Bertsekas is tested experimentally. Parallel algorithms using the auction approach are developed and tested. Both the sequential and parallel auction algorithms perform significantly worse than a state-of-the-art Dijkstra-l......-like reference algorithm. Experiments are run on a distributed-memory MIMD class Meiko parallel computer....

  13. Control dynamics of interaction quenched ultracold bosons in periodically driven lattices

    Science.gov (United States)

    Mistakidis, Simeon; Schmelcher, Peter; Group of Fundamental Processes in Quantum Physics Team

    2016-05-01

    The out-of-equilibrium dynamics of ultracold bosons following an interaction quench upon a periodically driven optical lattice is investigated. It is shown that an interaction quench triggers the inter-well tunneling dynamics, while for the intra-well dynamics breathing and cradle-like processes can be generated. In particular, the occurrence of a resonance between the cradle and tunneling modes is revealed. On the other hand, the employed periodic driving enforces the bosons in the mirror wells to oscillate out-of-phase and to exhibit a dipole mode, while in the central well the cloud experiences a breathing mode. The dynamical behaviour of the system is investigated with respect to the driving frequency revealing a resonant behaviour of the intra-well dynamics. To drive the system in a highly non-equilibrium state an interaction quench upon the driving is performed giving rise to admixtures of excitations in the outer wells, an enhanced breathing in the center and an amplification of the tunneling dynamics. As a result of the quench the system experiences multiple resonances between the inter- and intra-well dynamics at different quench amplitudes. Deutsche Forschungsgemeinschaft, SFB 925 ``Light induced dynamics and control of correlated quantum systems''.

  14. Non-linear second-order periodic systems with non-smooth potential

    Indian Academy of Sciences (India)

    In this paper we study second order non-linear periodic systems driven by the ordinary vector -Laplacian with a non-smooth, locally Lipschitz potential function. Our approach is variational and it is based on the non-smooth critical point theory. We prove existence and multiplicity results under general growth conditions on ...

  15. Non-linear second-order periodic systems with non-smooth potential

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    Abstract. In this paper we study second order non-linear periodic systems driven by the ordinary vector p-Laplacian with a non-smooth, locally Lipschitz potential function. Our approach is variational and it is based on the non-smooth critical point theory. We prove existence and multiplicity results under general growth ...

  16. Study on k-shortest paths with behavioral impedance domain from the intermodal public transportation system perspective

    OpenAIRE

    Pereira, Hernane Borges de Barros; Pérez Vidal, Lluís; Lozada, Eleazar G. Madrid

    2003-01-01

    Behavioral impedance domain consists of a theory on route planning for pedestrians, within which constraint management is considered. The goal of this paper is to present the k-shortest path model using the behavioral impedance approach. After the mathematical model building, optimization problem and resolution problem by a behavioral impedance algorithm, it is discussed how behavioral impedance cost function is embedded in the k-shortest path model. From the pedestrian's route planning persp...

  17. Differences in physical environmental characteristics between adolescents' actual and shortest cycling routes: a study using a Google Street View-based audit.

    Science.gov (United States)

    Verhoeven, Hannah; Van Hecke, Linde; Van Dyck, Delfien; Baert, Tim; Van de Weghe, Nico; Clarys, Peter; Deforche, Benedicte; Van Cauwenberg, Jelle

    2018-05-29

    The objective evaluation of the physical environmental characteristics (e.g. speed limit, cycling infrastructure) along adolescents' actual cycling routes remains understudied, although it may provide important insights into why adolescents prefer one cycling route over another. The present study aims to gain insight into the physical environmental characteristics determining the route choice of adolescent cyclists by comparing differences in physical environmental characteristics between their actual cycling routes and the shortest possible cycling routes. Adolescents (n = 204; 46.5% boys; 14.4 ± 1.2 years) recruited at secondary schools in and around Ghent (city in Flanders, northern part of Belgium) were instructed to wear a Global Positioning System device in order to identify cycling trips. For all identified cycling trips, the shortest possible route that could have been taken was calculated. Actual cycling routes that were not the shortest possible cycling routes were divided into street segments. Segments were audited with a Google Street View-based tool to assess physical environmental characteristics along actual and shortest cycling routes. Out of 160 actual cycling trips, 73.1% did not differ from the shortest possible cycling route. For actual cycling routes that were not the shortest cycling route, a speed limit of 30 km/h, roads having few buildings with windows on the street side and roads without cycle lane were more frequently present compared to the shortest possible cycling routes. A mixed land use, roads with commercial destinations, arterial roads, cycle lanes separated from traffic by white lines, small cycle lanes and cycle lanes covered by lighting were less frequently present along actual cycling routes compared to the shortest possible cycling routes. Results showed that distance mainly determines the route along which adolescents cycle. In addition, adolescents cycled more along residential streets (even if no cycle lane was

  18. Analysis of the asymmetric shortest queue problem : part 2: numerical analysis

    NARCIS (Netherlands)

    Adan, I.J.B.F.; Wessels, J.; Zijm, W.H.M.

    1990-01-01

    In this paper we study a system consisting of two parallel servers with different service rates. Jobs arrive according to a Poisson stream and generate an exponentially distributed workload. On arrival a job joins the shortest queue and in case both queues have equal lengths, he joins the first

  19. Analysis of the asymmetric shortest queue problem : Part 1: theoretical analysis

    NARCIS (Netherlands)

    Adan, I.J.B.F.; Wessels, J.; Zijm, W.H.M.

    1990-01-01

    In this paper we study a system consisting of two parallel servers with different service rates. Jobs arrive according to a Poisson stream and generate an exponentially distributed workload. On arrival a job joins the shortest queue and in case both queues have equal lengths. be joins the first

  20. Comparison of Periodized and Non-Periodized Resistance Training on Maximal Strength: A Meta-Analysis.

    Science.gov (United States)

    Williams, Tyler D; Tolusso, Danilo V; Fedewa, Michael V; Esco, Michael R

    2017-10-01

    Periodization is a logical method of organizing training into sequential phases and cyclical time periods in order to increase the potential for achieving specific performance goals while minimizing the potential for overtraining. Periodized resistance training plans are proposed to be superior to non-periodized training plans for enhancing maximal strength. The primary aim of this study was to examine the previous literature comparing periodized resistance training plans to non-periodized resistance training plans and determine a quantitative estimate of effect on maximal strength. All studies included in the meta-analysis met the following inclusion criteria: (1) peer-reviewed publication; (2) published in English; (3) comparison of a periodized resistance training group to a non-periodized resistance training group; (4) maximal strength measured by 1-repetition maximum (1RM) squat, bench press, or leg press. Data were extracted and independently coded by two authors. Random-effects models were used to aggregate a mean effect size (ES), 95% confidence intervals (CIs) and potential moderators. The cumulative results of 81 effects gathered from 18 studies published between 1988 and 2015 indicated that the magnitude of improvement in 1RM following periodized resistance training was greater than non-periodized resistance training (ES = 0.43, 95% CI 0.27-0.58; P training status (β = -0.59; P = 0.0305), study length (β = 0.03; P = 0.0067), and training frequency (β = 0.46; P = 0.0123) were associated with a change in 1RM. These results indicate that undulating programs were more favorable for strength gains. Improvements in 1RM were greater among untrained participants. Additionally, higher training frequency and longer study length were associated with larger improvements in 1RM. These results suggest that periodized resistance training plans have a moderate effect on 1RM compared to non-periodized training plans. Variation in training stimuli

  1. Establishment Of The Shortest Route A Prototype For Facilitation In Road Network

    Directory of Open Access Journals (Sweden)

    Sumaira Yousuf Khan

    2015-08-01

    Full Text Available Calculating the shortest path between two locations in a road network is a significant problem in network analysis. Roads play a pivotal role in day to day activities of masses live in places and areas. They travel for various purposes that are to study to work to shop and to supply their goods and the like from one place to another place. Even in this modern era roads remain one of the mediums used most frequently for travel and transportation. Being ignorant of the shortest routes people sometimes have to travel long distances consume extra precious time money and bare undesirable mental stress. Karachi is the second most populated and the seventh biggest city of the world. It is the central place of Pakistan which is famous for industry banking trade and economic activity and there are places which frequently visit by the inhabitants for their miscellaneous requirements. Federal Board of Revenue FBR is one of the departments that deal with taxation and revenue generation in the country. A common man residing near or distant areas often visit FBR to settle their business property and tax related issues. In order to facilitate the masses an effort is being made to develop a prototype based on Dijkstras Algorithm DA to establish a shortest route that will help individuals in navigation and subsequently alleviate difficulties faced by them in travelling road networks.

  2. Beam-wave interaction in periodic and quasi-periodic structures. 2. ed.

    International Nuclear Information System (INIS)

    Schaechter, Levi

    2011-01-01

    The main theme of this book is the interaction of electrons with electromagnetic waves in the presence of periodic and quasi-periodic structures in vacuum, in view of applications in the design and operation of particle accelerators. The first part of the book is concerned with the textbook-like presentation of the basic material, in particular reviewing elementary electromagnetic phenomena and electron dynamics. The second part of the book describes the current models for beam-wave interactions with periodic and quasi-periodic structures. This is the basis for introducing, in the last part of the book, a number of particle and radiation sources that rest on these principles, in particular the free-electron laser, wake-field acceleration schemes and a number of other advanced particle accelerator concepts. This second edition brings this fundamental text up-to-date in view of the enormous advances that have been made over the last decade since the first edition was published. All chapters, as well as the bibliography, have been significantly revised and extended, and the number of end-of-chapter exercises has been further increased to enhance this book's usefulness for teaching specialized graduate courses. (orig.)

  3. Efficient evaluation of shortest travel-time path queries through spatial mashups

    KAUST Repository

    Zhang, Detian

    2017-01-07

    In the real world, the route/path with the shortest travel time in a road network is more meaningful than that with the shortest network distance for location-based services (LBS). However, not every LBS provider has adequate resources to compute/estimate travel time for routes by themselves. A cost-effective way for LBS providers to estimate travel time for routes is to issue external route requests to Web mapping services (e.g., Google Maps, Bing Maps, and MapQuest Maps). Due to the high cost of processing such external route requests and the usage limits of Web mapping services, we take the advantage of direction sharing, parallel requesting and waypoints supported by Web mapping services to reduce the number of external route requests and the query response time for shortest travel-time route queries in this paper. We first give the definition of sharing ability to reflect the possibility of sharing the direction information of a route with others, and find out the queries that their query routes are independent with each other for parallel processing. Then, we model the problem of selecting the optimal waypoints for an external route request as finding the longest simple path in a weighted complete digraph. As it is a MAX SNP-hard problem, we propose a greedy algorithm with performance guarantee to find the best set of waypoints in an external route request. We evaluate the performance of our approach using a real Web mapping service, a real road network, real and synthetic data sets. Experimental results show the efficiency, scalability, and applicability of our approach.

  4. Efficient evaluation of shortest travel-time path queries through spatial mashups

    KAUST Repository

    Zhang, Detian; Chow, Chi-Yin; Liu, An; Zhang, Xiangliang; Ding, Qingzhu; Li, Qing

    2017-01-01

    In the real world, the route/path with the shortest travel time in a road network is more meaningful than that with the shortest network distance for location-based services (LBS). However, not every LBS provider has adequate resources to compute/estimate travel time for routes by themselves. A cost-effective way for LBS providers to estimate travel time for routes is to issue external route requests to Web mapping services (e.g., Google Maps, Bing Maps, and MapQuest Maps). Due to the high cost of processing such external route requests and the usage limits of Web mapping services, we take the advantage of direction sharing, parallel requesting and waypoints supported by Web mapping services to reduce the number of external route requests and the query response time for shortest travel-time route queries in this paper. We first give the definition of sharing ability to reflect the possibility of sharing the direction information of a route with others, and find out the queries that their query routes are independent with each other for parallel processing. Then, we model the problem of selecting the optimal waypoints for an external route request as finding the longest simple path in a weighted complete digraph. As it is a MAX SNP-hard problem, we propose a greedy algorithm with performance guarantee to find the best set of waypoints in an external route request. We evaluate the performance of our approach using a real Web mapping service, a real road network, real and synthetic data sets. Experimental results show the efficiency, scalability, and applicability of our approach.

  5. A Universal Concept for Robust Solving of Shortest Path Problems in Dynamically Reconfigurable Graphs

    Directory of Open Access Journals (Sweden)

    Jean Chamberlain Chedjou

    2015-01-01

    Full Text Available This paper develops a flexible analytical concept for robust shortest path detection in dynamically reconfigurable graphs. The concept is expressed by a mathematical model representing the shortest path problem solver. The proposed mathematical model is characterized by three fundamental parameters expressing (a the graph topology (through the “incidence matrix”, (b the edge weights (with dynamic external weights’ setting capability, and (c the dynamic reconfigurability through external input(s of the source-destination nodes pair. In order to demonstrate the universality of the developed concept, a general algorithm is proposed to determine the three fundamental parameters (of the mathematical model developed for all types of graphs regardless of their topology, magnitude, and size. It is demonstrated that the main advantage of the developed concept is that arc costs, the origin-destination pair setting, and the graph topology are dynamically provided by external commands, which are inputs of the shortest path solver model. This enables high flexibility and full reconfigurability of the developed concept, without any retraining need. To validate the concept developed, benchmarking is performed leading to a comparison of its performance with the performances of two well-known concepts based on neural networks.

  6. Mode-coupling of interaction quenched ultracold bosons in periodically driven lattices

    Science.gov (United States)

    Mistakidis, Simeon; Schmelcher, Peter

    2016-05-01

    The out-of-equilibrium dynamics of interaction quenched finite ultracold bosonic ensembles in periodically driven one-dimensional optical lattices is investigated. As a first attempt a brief analysis of the dynamics caused exclusively by the periodically driven lattice is presented and the induced low-lying modes are introduced. It is shown that the periodic driving enforces the bosons in the outer wells to exhibit out-of-phase dipole-like modes, while in the central well the cloud experiences a local-breathing mode. The dynamical behavior of the system is investigated with respect to the driving frequency, revealing a resonant-like behavior of the intra-well dynamics. Subsequently, we drive the system to a highly non-equilibrium state by performing an interaction quench upon the periodically driven lattice. This protocol gives rise to admixtures of excitations in the outer wells, an enhanced breathing in the center and an amplification of the tunneling dynamics. As a result (of the quench) the system experiences multiple resonances between the inter- and intra-well dynamics at different quench amplitudes. Finally, our study reveals that the position of the resonances can be adjusted e.g. via the driving frequency or the atom number manifesting their many-body nature. Deutsche Forschungsgemeinschaft (DFG) in the framework of the SFB 925 ``Light induced dynamics and control of correlated quantum systems''.

  7. A Shortest-Path-Based Method for the Analysis and Prediction of Fruit-Related Genes in Arabidopsis thaliana.

    Science.gov (United States)

    Zhu, Liucun; Zhang, Yu-Hang; Su, Fangchu; Chen, Lei; Huang, Tao; Cai, Yu-Dong

    2016-01-01

    Biologically, fruits are defined as seed-bearing reproductive structures in angiosperms that develop from the ovary. The fertilization, development and maturation of fruits are crucial for plant reproduction and are precisely regulated by intrinsic genetic regulatory factors. In this study, we used Arabidopsis thaliana as a model organism and attempted to identify novel genes related to fruit-associated biological processes. Specifically, using validated genes, we applied a shortest-path-based method to identify several novel genes in a large network constructed using the protein-protein interactions observed in Arabidopsis thaliana. The described analyses indicate that several of the discovered genes are associated with fruit fertilization, development and maturation in Arabidopsis thaliana.

  8. Shortest triplet clustering: reconstructing large phylogenies using representative sets

    Directory of Open Access Journals (Sweden)

    Sy Vinh Le

    2005-04-01

    Full Text Available Abstract Background Understanding the evolutionary relationships among species based on their genetic information is one of the primary objectives in phylogenetic analysis. Reconstructing phylogenies for large data sets is still a challenging task in Bioinformatics. Results We propose a new distance-based clustering method, the shortest triplet clustering algorithm (STC, to reconstruct phylogenies. The main idea is the introduction of a natural definition of so-called k-representative sets. Based on k-representative sets, shortest triplets are reconstructed and serve as building blocks for the STC algorithm to agglomerate sequences for tree reconstruction in O(n2 time for n sequences. Simulations show that STC gives better topological accuracy than other tested methods that also build a first starting tree. STC appears as a very good method to start the tree reconstruction. However, all tested methods give similar results if balanced nearest neighbor interchange (BNNI is applied as a post-processing step. BNNI leads to an improvement in all instances. The program is available at http://www.bi.uni-duesseldorf.de/software/stc/. Conclusion The results demonstrate that the new approach efficiently reconstructs phylogenies for large data sets. We found that BNNI boosts the topological accuracy of all methods including STC, therefore, one should use BNNI as a post-processing step to get better topological accuracy.

  9. The Resource constrained shortest path problem implemented in a lazy functional language

    NARCIS (Netherlands)

    Hartel, Pieter H.; Glaser, Hugh

    The resource constrained shortest path problem is an NP-hard problem for which many ingenious algorithms have been developed. These algorithms are usually implemented in Fortran or another imperative programming language. We have implemented some of the simpler algorithms in a lazy functional

  10. Floyd-warshall algorithm to determine the shortest path based on android

    Science.gov (United States)

    Ramadiani; Bukhori, D.; Azainil; Dengen, N.

    2018-04-01

    The development of technology has made all areas of life easier now, one of which is the ease of obtaining geographic information. The use of geographic information may vary according to need, for example, the digital map learning, navigation systems, observations area, and much more. With the support of adequate infrastructure, almost no one will ever get lost to a destination even to foreign places or that have never been visited before. The reasons why many institutions and business entities use technology to improve services to consumers and to streamline the production process undertaken and so forth. Speaking of the efficient, there are many elements related to efficiency in navigation systems, and one of them is the efficiency in terms of distance. The shortest distance determination algorithm required in this research is used Floyd-Warshall Algorithm. Floyd-Warshall algorithm is the algorithm to find the fastest path and the shortest distance between 2 nodes, while the program is intended to find the path of more than 2 nodes.

  11. An Efficient Shortest Path Routing Algorithm for Directed Indoor Environments

    Directory of Open Access Journals (Sweden)

    Sultan Alamri

    2018-03-01

    Full Text Available Routing systems for outdoor space have become the focus of many research works. Such routing systems are based on spatial road networks where moving objects (such as cars are affected by the directed roads and the movement of traffic, which may include traffic jams. Indoor routing, on the other hand, must take into account the features of indoor space such as walls and rooms. In this paper, we take indoor routing in a new direction whereby we consider the features that a building has in common with outdoor spaces. Inside some buildings, there may be directed floors where moving objects must move in a certain direction through directed corridors in order to reach a certain location. For example, on train platforms or in museums, movement in the corridors may be directed. In these directed floor spaces, a routing system enabling a visitor to take the shortest path to a certain location is essential. Therefore, this work proposes a new approach for buildings with directed indoor spaces, where each room can be affected by the density of the moving objects. The proposed system obtains the shortest path between objects or rooms taking into consideration the directed indoor space and the capacity of the objects to move within each room/cell.

  12. Degree distribution of shortest path trees and bias of network sampling algorithms

    NARCIS (Netherlands)

    Bhamidi, S.; Goodman, J.A.; Hofstad, van der R.W.; Komjáthy, J.

    2013-01-01

    In this article, we explicitly derive the limiting distribution of the degree distribution of the shortest path tree from a single source on various random network models with edge weights. We determine the power-law exponent of the degree distribution of this tree and compare it to the degree

  13. Degree distribution of shortest path trees and bias of network sampling algorithms

    NARCIS (Netherlands)

    Bhamidi, S.; Goodman, J.A.; Hofstad, van der R.W.; Komjáthy, J.

    2015-01-01

    In this article, we explicitly derive the limiting degree distribution of the shortest path tree from a single source on various random network models with edge weights. We determine the asymptotics of the degree distribution for large degrees of this tree and compare it to the degree distribution

  14. Training shortest-path tractography: Automatic learning of spatial priors

    DEFF Research Database (Denmark)

    Kasenburg, Niklas; Liptrot, Matthew George; Reislev, Nina Linde

    2016-01-01

    Tractography is the standard tool for automatic delineation of white matter tracts from diffusion weighted images. However, the output of tractography often requires post-processing to remove false positives and ensure a robust delineation of the studied tract, and this demands expert prior...... knowledge. Here we demonstrate how such prior knowledge, or indeed any prior spatial information, can be automatically incorporated into a shortest-path tractography approach to produce more robust results. We describe how such a prior can be automatically generated (learned) from a population, and we...

  15. Calculating Graph Algorithms for Dominance and Shortest Path

    DEFF Research Database (Denmark)

    Sergey, Ilya; Midtgaard, Jan; Clarke, Dave

    2012-01-01

    We calculate two iterative, polynomial-time graph algorithms from the literature: a dominance algorithm and an algorithm for the single-source shortest path problem. Both algorithms are calculated directly from the definition of the properties by fixed-point fusion of (1) a least fixed point...... expressing all finite paths through a directed graph and (2) Galois connections that capture dominance and path length. The approach illustrates that reasoning in the style of fixed-point calculus extends gracefully to the domain of graph algorithms. We thereby bridge common practice from the school...... of program calculation with common practice from the school of static program analysis, and build a novel view on iterative graph algorithms as instances of abstract interpretation...

  16. A 2D analytical cylindrical gate tunnel FET (CG-TFET) model: impact of shortest tunneling distance

    Science.gov (United States)

    Dash, S.; Mishra, G. P.

    2015-09-01

    A 2D analytical tunnel field-effect transistor (FET) potential model with cylindrical gate (CG-TFET) based on the solution of Laplace’s equation is proposed. The band-to-band tunneling (BTBT) current is derived by the help of lateral electric field and the shortest tunneling distance. However, the analysis is extended to obtain the subthreshold swing (SS) and transfer characteristics of the device. The dependency of drain current, SS and transconductance on gate voltage and shortest tunneling distance is discussed. Also, the effect of scaling the gate oxide thickness and the cylindrical body diameter on the electrical parameters of the device is analyzed.

  17. A 2D analytical cylindrical gate tunnel FET (CG-TFET) model: impact of shortest tunneling distance

    International Nuclear Information System (INIS)

    Dash, S; Mishra, G P

    2015-01-01

    A 2D analytical tunnel field-effect transistor (FET) potential model with cylindrical gate (CG-TFET) based on the solution of Laplace’s equation is proposed. The band-to-band tunneling (BTBT) current is derived by the help of lateral electric field and the shortest tunneling distance. However, the analysis is extended to obtain the subthreshold swing (SS) and transfer characteristics of the device. The dependency of drain current, SS and transconductance on gate voltage and shortest tunneling distance is discussed. Also, the effect of scaling the gate oxide thickness and the cylindrical body diameter on the electrical parameters of the device is analyzed. (paper)

  18. Effects of age, gender, and stimulus presentation period on visual short-term memory.

    Science.gov (United States)

    Kunimi, Mitsunobu

    2016-01-01

    This study focused on age-related changes in visual short-term memory using visual stimuli that did not allow verbal encoding. Experiment 1 examined the effects of age and the length of the stimulus presentation period on visual short-term memory function. Experiment 2 examined the effects of age, gender, and the length of the stimulus presentation period on visual short-term memory function. The worst memory performance and the largest performance difference between the age groups were observed in the shortest stimulus presentation period conditions. The performance difference between the age groups became smaller as the stimulus presentation period became longer; however, it did not completely disappear. Although gender did not have a significant effect on d' regardless of the presentation period in the young group, a significant gender-based difference was observed for stimulus presentation periods of 500 ms and 1,000 ms in the older group. This study indicates that the decline in visual short-term memory observed in the older group is due to the interaction of several factors.

  19. Children's route choice during active transportation to school: Difference between shortest and actual route

    NARCIS (Netherlands)

    Dessing, D.; Vries, S.I. de; Hegeman, G.; Verhagen, E.; Mechelen, W. van; Pierik, F.H.

    2016-01-01

    Background: The purpose of this study is to increase our understanding of environmental correlates that are associated with route choice during active transportation to school (ATS) by comparing characteristics of actual walking and cycling routes between home and school with the shortest possible

  20. Approaching the Brachistochrone Using Inclined Planes--Striving for Shortest or Equal Travelling Times

    Science.gov (United States)

    Theilmann, Florian

    2017-01-01

    The classical "brachistochrone" problem asks for the path on which a mobile point M just driven by its own gravity will travel in the shortest possible time between two given points "A" and "B." The resulting curve, the cycloid, will also be the "tautochrone" curve, i.e. the travelling time of the mobile…

  1. DESIGNING APPLICATION OF ANT COLONY SYSTEM ALGORITHM FOR THE SHORTEST ROUTE OF BANDA ACEH CITY AND ACEH BESAR REGENCY TOURISM BY USING GRAPHICAL USER INTERFACE MATLAB

    Directory of Open Access Journals (Sweden)

    Durisman Durisman

    2017-09-01

    Full Text Available Banda Aceh city and Aceh Besar Regency are two of the leading tourism areas located in the province of Aceh. For travelling, there are some important things to be considered, such as determining schedule and distance of tourism. Every tourist certainly chooses the shortest route to reach the destination since it can save time, energy, and money. The purpose of this reserach is to develop a method that can be used in calculating the shortest route and applied to the tourism of Banda Aceh city and Aceh Besar regency. In this reserach, Ant Colony Optimization algorithm is used to determine the shortest route to tourism of Banda Aceh city and Aceh Besar regency. From the analysis made by using both manual calculation and  GUI MATLAB program application test, the shortest route can be obtained with a minimum distance of 120.85 km in one travel. Based on the test result, the application for tourism (in Banda Aceh city and Aceh Besar regency shortest route searching built by utilizing the Ant Colony Optimization algorithm can find optimal route.  Keyword: tourism, the shortest route, Ant Colony Optimization

  2. Performance analysis of parallel identical machines with a generalized shortest queue arrival mechanism

    NARCIS (Netherlands)

    van Houtum, Geert-Jan; Adan, I.J.B.F.; Wessels, J.; Zijm, Willem H.M.

    In this paper we study a production system consisting of a group of parallel machines producing multiple job types. Each machine has its own queue and it can process a restricted set of job types only. On arrival a job joins the shortest queue among all queues capable of serving that job. Under the

  3. The drug target genes show higher evolutionary conservation than non-target genes.

    Science.gov (United States)

    Lv, Wenhua; Xu, Yongdeng; Guo, Yiying; Yu, Ziqi; Feng, Guanglong; Liu, Panpan; Luan, Meiwei; Zhu, Hongjie; Liu, Guiyou; Zhang, Mingming; Lv, Hongchao; Duan, Lian; Shang, Zhenwei; Li, Jin; Jiang, Yongshuai; Zhang, Ruijie

    2016-01-26

    Although evidence indicates that drug target genes share some common evolutionary features, there have been few studies analyzing evolutionary features of drug targets from an overall level. Therefore, we conducted an analysis which aimed to investigate the evolutionary characteristics of drug target genes. We compared the evolutionary conservation between human drug target genes and non-target genes by combining both the evolutionary features and network topological properties in human protein-protein interaction network. The evolution rate, conservation score and the percentage of orthologous genes of 21 species were included in our study. Meanwhile, four topological features including the average shortest path length, betweenness centrality, clustering coefficient and degree were considered for comparison analysis. Then we got four results as following: compared with non-drug target genes, 1) drug target genes had lower evolutionary rates; 2) drug target genes had higher conservation scores; 3) drug target genes had higher percentages of orthologous genes and 4) drug target genes had a tighter network structure including higher degrees, betweenness centrality, clustering coefficients and lower average shortest path lengths. These results demonstrate that drug target genes are more evolutionarily conserved than non-drug target genes. We hope that our study will provide valuable information for other researchers who are interested in evolutionary conservation of drug targets.

  4. On natural frequencies of non-uniform beams modulated by finite periodic cells

    International Nuclear Information System (INIS)

    Xu, Yanlong; Zhou, Xiaoling; Wang, Wei; Wang, Longqi; Peng, Fujun; Li, Bin

    2016-01-01

    It is well known that an infinite periodic beam can support flexural wave band gaps. However, in real applications, the number of the periodic cells is always limited. If a uniform beam is replaced by a non-uniform beam with finite periodicity, the vibration changes are vital by mysterious. This paper employs the transfer matrix method (TMM) to study the natural frequencies of the non-uniform beams with modulation by finite periodic cells. The effects of the amounts, cross section ratios, and arrangement forms of the periodic cells on the natural frequencies are explored. The relationship between the natural frequencies of the non-uniform beams with finite periodicity and the band gap boundaries of the corresponding infinite periodic beam is also investigated. Numerical results and conclusions obtained here are favorable for designing beams with good vibration control ability. - Highlights: • The transfer matrix method to study the natural frequencies of the finite periodic non-uniform beams is derived. • The transfer matrix method to study the band gaps of the infinite periodic non-uniform beams is derived. • The effects of the periodic cells on the natural frequencies are explored. • The relationships of the natural frequencies and band gap boundaries are investigated.

  5. On natural frequencies of non-uniform beams modulated by finite periodic cells

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Yanlong, E-mail: xuyanlong@nwpu.edu.cn [School of Aeronautics, Northwestern Polytechnical University, Xi' an 710072, Shaanxi (China); Zhou, Xiaoling [Shanghai Institute of Aerospace System Engineering, Shanghai 201109 (China); Wang, Wei [School of Aeronautics, Northwestern Polytechnical University, Xi' an 710072, Shaanxi (China); Wang, Longqi [School of Civil & Environmental Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 (Singapore); Peng, Fujun [Shanghai Institute of Aerospace System Engineering, Shanghai 201109 (China); Li, Bin [School of Aeronautics, Northwestern Polytechnical University, Xi' an 710072, Shaanxi (China)

    2016-09-23

    It is well known that an infinite periodic beam can support flexural wave band gaps. However, in real applications, the number of the periodic cells is always limited. If a uniform beam is replaced by a non-uniform beam with finite periodicity, the vibration changes are vital by mysterious. This paper employs the transfer matrix method (TMM) to study the natural frequencies of the non-uniform beams with modulation by finite periodic cells. The effects of the amounts, cross section ratios, and arrangement forms of the periodic cells on the natural frequencies are explored. The relationship between the natural frequencies of the non-uniform beams with finite periodicity and the band gap boundaries of the corresponding infinite periodic beam is also investigated. Numerical results and conclusions obtained here are favorable for designing beams with good vibration control ability. - Highlights: • The transfer matrix method to study the natural frequencies of the finite periodic non-uniform beams is derived. • The transfer matrix method to study the band gaps of the infinite periodic non-uniform beams is derived. • The effects of the periodic cells on the natural frequencies are explored. • The relationships of the natural frequencies and band gap boundaries are investigated.

  6. A technique to detect periodic and non-periodic ultra-rapid flux time variations with standard radio-astronomical data

    Science.gov (United States)

    Borra, Ermanno F.; Romney, Jonathan D.; Trottier, Eric

    2018-06-01

    We demonstrate that extremely rapid and weak periodic and non-periodic signals can easily be detected by using the autocorrelation of intensity as a function of time. We use standard radio-astronomical observations that have artificial periodic and non-periodic signals generated by the electronics of terrestrial origin. The autocorrelation detects weak signals that have small amplitudes because it averages over long integration times. Another advantage is that it allows a direct visualization of the shape of the signals, while it is difficult to see the shape with a Fourier transform. Although Fourier transforms can also detect periodic signals, a novelty of this work is that we demonstrate another major advantage of the autocorrelation, that it can detect non-periodic signals while the Fourier transform cannot. Another major novelty of our work is that we use electric fields taken in a standard format with standard instrumentation at a radio observatory and therefore no specialized instrumentation is needed. Because the electric fields are sampled every 15.625 ns, they therefore allow detection of very rapid time variations. Notwithstanding the long integration times, the autocorrelation detects very rapid intensity variations as a function of time. The autocorrelation could also detect messages from Extraterrestrial Intelligence as non-periodic signals.

  7. Shortest path problem on a grid network with unordered intermediate points

    Science.gov (United States)

    Saw, Veekeong; Rahman, Amirah; Eng Ong, Wen

    2017-10-01

    We consider a shortest path problem with single cost factor on a grid network with unordered intermediate points. A two stage heuristic algorithm is proposed to find a feasible solution path within a reasonable amount of time. To evaluate the performance of the proposed algorithm, computational experiments are performed on grid maps of varying size and number of intermediate points. Preliminary results for the problem are reported. Numerical comparisons against brute forcing show that the proposed algorithm consistently yields solutions that are within 10% of the optimal solution and uses significantly less computation time.

  8. Shared periodic performer movements coordinate interactions in duo improvisations

    Science.gov (United States)

    Jakubowski, Kelly; Moran, Nikki; Keller, Peter E.

    2018-01-01

    Human interaction involves the exchange of temporally coordinated, multimodal cues. Our work focused on interaction in the visual domain, using music performance as a case for analysis due to its temporally diverse and hierarchical structures. We made use of two improvising duo datasets—(i) performances of a jazz standard with a regular pulse and (ii) non-pulsed, free improvizations—to investigate whether human judgements of moments of interaction between co-performers are influenced by body movement coordination at multiple timescales. Bouts of interaction in the performances were manually annotated by experts and the performers’ movements were quantified using computer vision techniques. The annotated interaction bouts were then predicted using several quantitative movement and audio features. Over 80% of the interaction bouts were successfully predicted by a broadband measure of the energy of the cross-wavelet transform of the co-performers’ movements in non-pulsed duos. A more complex model, with multiple predictors that captured more specific, interacting features of the movements, was needed to explain a significant amount of variance in the pulsed duos. The methods developed here have key implications for future work on measuring visual coordination in musical ensemble performances, and can be easily adapted to other musical contexts, ensemble types and traditions. PMID:29515867

  9. Atomic adsorption on pristine graphene along the Periodic Table of Elements - From PBE to non-local functionals

    Science.gov (United States)

    Pašti, Igor A.; Jovanović, Aleksandar; Dobrota, Ana S.; Mentus, Slavko V.; Johansson, Börje; Skorodumova, Natalia V.

    2018-04-01

    The understanding of atomic adsorption on graphene is of high importance for many advanced technologies. Here we present a complete database of the atomic adsorption energies for the elements of the Periodic Table up to the atomic number 86 (excluding lanthanides) on pristine graphene. The energies have been calculated using the projector augmented wave (PAW) method with PBE, long-range dispersion interaction corrected PBE (PBE+D2, PBE+D3) as well as non-local vdW-DF2 approach. The inclusion of dispersion interactions leads to an exothermic adsorption for all the investigated elements. Dispersion interactions are found to be of particular importance for the adsorption of low atomic weight earth alkaline metals, coinage and s-metals (11th and 12th groups), high atomic weight p-elements and noble gases. We discuss the observed adsorption trends along the groups and rows of the Periodic Table as well some computational aspects of modelling atomic adsorption on graphene.

  10. Specific non-monotonous interactions increase persistence of ecological networks.

    Science.gov (United States)

    Yan, Chuan; Zhang, Zhibin

    2014-03-22

    The relationship between stability and biodiversity has long been debated in ecology due to opposing empirical observations and theoretical predictions. Species interaction strength is often assumed to be monotonically related to population density, but the effects on stability of ecological networks of non-monotonous interactions that change signs have not been investigated previously. We demonstrate that for four kinds of non-monotonous interactions, shifting signs to negative or neutral interactions at high population density increases persistence (a measure of stability) of ecological networks, while for the other two kinds of non-monotonous interactions shifting signs to positive interactions at high population density decreases persistence of networks. Our results reveal a novel mechanism of network stabilization caused by specific non-monotonous interaction types through either increasing stable equilibrium points or reducing unstable equilibrium points (or both). These specific non-monotonous interactions may be important in maintaining stable and complex ecological networks, as well as other networks such as genes, neurons, the internet and human societies.

  11. Periodic orbits and non-integrability of Henon-Heiles systems

    International Nuclear Information System (INIS)

    Llibre, Jaume; Jimenez-Lara, Lidia

    2011-01-01

    We apply the averaging theory of second order to study the periodic orbits for a generalized Henon-Heiles system with two parameters, which contains the classical Henon-Heiles system. Two main results are shown. The first result provides sufficient conditions on the two parameters of these generalized systems, which guarantee that at any positive energy level, the Hamiltonian system has periodic orbits. These periodic orbits form in the whole phase space a continuous family of periodic orbits parameterized by the energy. The second result shows that for the non-integrable Henon-Heiles systems in the sense of Liouville-Arnol'd, which have the periodic orbits analytically found with averaging theory, cannot exist any second first integral of class C 1 . In particular, for any second first integral of class C 1 , we prove that the classical Henon-Heiles system and many generalizations of it are not integrable in the sense of Liouville-Arnol'd. Moreover, the tools we use for studying the periodic orbits and the non-Liouville-Arnol'd integrability can be applied to Hamiltonian systems with an arbitrary number of degrees of freedom.

  12. An Optimal Non-Interactive Message Authentication Protocol

    OpenAIRE

    Pasini, Sylvain; Vaudenay, Serge

    2006-01-01

    Vaudenay recently proposed a message authentication protocol which is interactive and based on short authenticated strings (SAS). We study here SAS-based non-interactive message authentication protocols (NIMAP). We start by the analysis of two popular non-interactive message authentication protocols. The first one is based on a collision-resistant hash function and was presented by Balfanz et al. The second protocol is based on a universal hash function family and was proposed by Gehrmann, Mi...

  13. The early period of the universal Fermi interaction

    International Nuclear Information System (INIS)

    Tiomno, J.

    1984-01-01

    A critical analysis of the contributions which lead, in the early period, to the discovery of the universality of Fermi-type weak interactions is made. In particular the current references to this universality as 'Puppi's triangle' are shown to be incorrect. (Author) [pt

  14. A shortest-path graph kernel for estimating gene product semantic similarity

    Directory of Open Access Journals (Sweden)

    Alvarez Marco A

    2011-07-01

    Full Text Available Abstract Background Existing methods for calculating semantic similarity between gene products using the Gene Ontology (GO often rely on external resources, which are not part of the ontology. Consequently, changes in these external resources like biased term distribution caused by shifting of hot research topics, will affect the calculation of semantic similarity. One way to avoid this problem is to use semantic methods that are "intrinsic" to the ontology, i.e. independent of external knowledge. Results We present a shortest-path graph kernel (spgk method that relies exclusively on the GO and its structure. In spgk, a gene product is represented by an induced subgraph of the GO, which consists of all the GO terms annotating it. Then a shortest-path graph kernel is used to compute the similarity between two graphs. In a comprehensive evaluation using a benchmark dataset, spgk compares favorably with other methods that depend on external resources. Compared with simUI, a method that is also intrinsic to GO, spgk achieves slightly better results on the benchmark dataset. Statistical tests show that the improvement is significant when the resolution and EC similarity correlation coefficient are used to measure the performance, but is insignificant when the Pfam similarity correlation coefficient is used. Conclusions Spgk uses a graph kernel method in polynomial time to exploit the structure of the GO to calculate semantic similarity between gene products. It provides an alternative to both methods that use external resources and "intrinsic" methods with comparable performance.

  15. Global asymptotical ω-periodicity of a fractional-order non-autonomous neural networks.

    Science.gov (United States)

    Chen, Boshan; Chen, Jiejie

    2015-08-01

    We study the global asymptotic ω-periodicity for a fractional-order non-autonomous neural networks. Firstly, based on the Caputo fractional-order derivative it is shown that ω-periodic or autonomous fractional-order neural networks cannot generate exactly ω-periodic signals. Next, by using the contraction mapping principle we discuss the existence and uniqueness of S-asymptotically ω-periodic solution for a class of fractional-order non-autonomous neural networks. Then by using a fractional-order differential and integral inequality technique, we study global Mittag-Leffler stability and global asymptotical periodicity of the fractional-order non-autonomous neural networks, which shows that all paths of the networks, starting from arbitrary points and responding to persistent, nonconstant ω-periodic external inputs, asymptotically converge to the same nonconstant ω-periodic function that may be not a solution. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Non-linear soil-structure interaction

    International Nuclear Information System (INIS)

    Wolf, J.P.

    1984-01-01

    The basic equation of motion to analyse the interaction of a non-linear structure and an irregular soil with the linear unbounded soil is formulated in the time domain. The contribution of the unbounded soil involves convolution integrals of the dynamic-stiffness coefficients in the time domain and the corresponding motions. As another possibility, a flexibility formulation fot the contribution of the unbounded soil using the dynamic-flexibility coefficients in the time domain, together with the direct-stiffness method for the structure and the irregular soil can be applied. As an example of a non-linear soil-structure-interaction analysis, the partial uplift of the basemat of a structure is examined. (Author) [pt

  17. External Data Structures for Shortest Path Queries on Planar Digraphs

    DEFF Research Database (Denmark)

    Arge, Lars; Toma, Laura

    2005-01-01

    In this paper we present space-query trade-offs for external memory data structures that answer shortest path queries on planar directed graphs. For any S = Ω(N 1 + ε) and S = O(N2/B), our main result is a family of structures that use S space and answer queries in O(N2/ S B) I/Os, thus obtaining...... optimal space-query product O(N2/B). An S space structure can be constructed in O(√S · sort(N)) I/Os, where sort(N) is the number of I/Os needed to sort N elements, B is the disk block size, and N is the size of the graph....

  18. Gaps in the spectrum of a periodic quantum graph with periodically distributed delta '-type interactions

    Czech Academy of Sciences Publication Activity Database

    Barseghyan, Diana; Khrabustovskyi, A.

    2015-01-01

    Roč. 48, č. 25 (2015), s. 255201 ISSN 1751-8113 Institutional support: RVO:61389005 Keywords : periodic quantum graphs * delta'-type interactions * spectral gaps Subject RIV: BE - Theoretical Physics Impact factor: 1.933, year: 2015

  19. Lecturers' and Students’ Perception on Learning Dijkstra’s Shortest Path Algorithm Through Mobile Devices

    Directory of Open Access Journals (Sweden)

    Mazyar Seraj

    2014-06-01

    Full Text Available In recent years, many studies have been carried out on how to engage and support students in e-learning environments. Portable devices such as Personal Digital Assistants (PDAs, Tablet PCs, mobile phones and other mobile equipment have been used as parts of electronic learning environments to facilitate learning and teaching for both lecturers and students. However, there is still a dearth of study investigating the effects of small screen interfaces on mobile-based learning environments. This study aims to address two objectives: (i investigate lecturer and student difficulties encountered in teaching-learning process in traditional face-to-face classroom settings, and (ii to explore lecturer and student perceptions about learning the subject through mobile devices. This paper presents the results of a qualitative study using structured interviews to investigate lecturer and student experiences and perceptions on teaching and learning Dijkstra’s shortest path algorithm via mobile devices. The interview insights were then used as inputs to define user requirements for a mobile learning prototype. The findings show that the lecturers and students raised many issues about interactivity and the flexibility of effective learning applications on small screen devices, especially for a technical subject.

  20. Non-Linear Dynamics and Fundamental Interactions

    CERN Document Server

    Khanna, Faqir

    2006-01-01

    The book is directed to researchers and graduate students pursuing an advanced degree. It provides details of techniques directed towards solving problems in non-linear dynamics and chos that are, in general, not amenable to a perturbative treatment. The consideration of fundamental interactions is a prime example where non-perturbative techniques are needed. Extension of these techniques to finite temperature problems is considered. At present these ideas are primarily used in a perturbative context. However, non-perturbative techniques have been considered in some specific cases. Experts in the field on non-linear dynamics and chaos and fundamental interactions elaborate the techniques and provide a critical look at the present status and explore future directions that may be fruitful. The text of the main talks will be very useful to young graduate students who are starting their studies in these areas.

  1. Comparison of Genetic Algorithm and Hill Climbing for Shortest Path Optimization Mapping

    Directory of Open Access Journals (Sweden)

    Fronita Mona

    2018-01-01

    Full Text Available Traveling Salesman Problem (TSP is an optimization to find the shortest path to reach several destinations in one trip without passing through the same city and back again to the early departure city, the process is applied to the delivery systems. This comparison is done using two methods, namely optimization genetic algorithm and hill climbing. Hill Climbing works by directly selecting a new path that is exchanged with the neighbour’s to get the track distance smaller than the previous track, without testing. Genetic algorithms depend on the input parameters, they are the number of population, the probability of crossover, mutation probability and the number of generations. To simplify the process of determining the shortest path supported by the development of software that uses the google map API. Tests carried out as much as 20 times with the number of city 8, 16, 24 and 32 to see which method is optimal in terms of distance and time computation. Based on experiments conducted with a number of cities 3, 4, 5 and 6 producing the same value and optimal distance for the genetic algorithm and hill climbing, the value of this distance begins to differ with the number of city 7. The overall results shows that these tests, hill climbing are more optimal to number of small cities and the number of cities over 30 optimized using genetic algorithms.

  2. Anomalous van der Waals-Casimir interactions on graphene: A concerted effect of temperature, retardation, and non-locality

    Science.gov (United States)

    Ambrosetti, Alberto; Silvestrelli, Pier Luigi

    2018-04-01

    Dispersion forces play a major role in graphene, largely influencing adhesion of adsorbate moieties and stabilization of functional multilayered structures. However, the reliable prediction of dispersion interactions on graphene up to the relevant ˜10 nm scale is an extremely challenging task: in fact, electromagnetic retardation effects and the highly non-local character of π electrons can imply sizeable qualitative variations of the interaction with respect to known pairwise approaches. Here we address both issues, determining the finite-temperature van der Waals (vdW)-Casimir interaction for point-like and extended adsorbates on graphene, explicitly accounting for the non-local dielectric permittivity. We find that temperature, retardation, and non-locality play a crucial role in determining the actual vdW scaling laws and the stability of both atomic and larger molecular adsorbates. Our results highlight the importance of these effects for a proper description of systems of current high interest, such as graphene interacting with biomolecules, and self-assembly of complex nanoscale structures. Due to the generality of our approach and the observed non-locality of other 2D materials, our results suggest non-trivial vdW interactions from hexagonal mono-layered materials from group 14 of the periodic table, to transition metal dichalcogenides.

  3. Real space method of powder diffraction for non-periodic and nearly periodic materials

    International Nuclear Information System (INIS)

    Egami, T.; Toby, B.H.; Dmowski, W.; Janot, C.; Jorgensen, J.D.

    1990-01-01

    The use of high-energy neutrons from pulsed or hot sources allows the method of atomic pair distribution analysis to be applied to the structural determination of crystalline as well as amorphous solids. This method complements the standard crystallographic methods in studying non-periodic aspects of solids with or without long range order

  4. Floquet prethermalization and regimes of heating in a periodically driven, interacting quantum system

    Science.gov (United States)

    Weidinger, Simon; Knap, Michael

    We study the regimes of heating in the periodically driven O (N) -model, which represents a generic model for interacting quantum many-body systems. By computing the absorbed energy with a non-equilibrium Keldysh Green's function approach, we establish three dynamical regimes: at short times a single-particle dominated regime, at intermediate times a stable Floquet prethermal regime in which the system ceases to absorb, and at parametrically late times a thermalizing regime. Our simulations suggest that in the thermalizing regime the absorbed energy grows algebraically in time with an the exponent that approaches the universal value of 1 / 2 , and is thus significantly slower than linear Joule heating. Our results demonstrate the parametric stability of prethermal states in a generic many-body system driven at frequencies that are comparable to its microscopic scales. This paves the way for realizing exotic quantum phases, such as time crystals or interacting topological phases, in the prethermal regime of interacting Floquet systems. We acknowledge support from the Technical University of Munich - Institute for Advanced Study, funded by the German Excellence Initiative and the European Union FP7 under Grant agreement 291763, and from the DFG Grant No. KN 1254/1-1.

  5. Non-reciprocal wave propagation in one-dimensional nonlinear periodic structures

    Directory of Open Access Journals (Sweden)

    Benbiao Luo

    2018-01-01

    Full Text Available We study a one-dimensional nonlinear periodic structure which contains two different spring stiffness and an identical mass in each period. The linear dispersion relationship we obtain indicates that our periodic structure has obvious advantages compared to other kinds of periodic structures (i.e. those with the same spring stiffness but two different mass, including its increased flexibility for manipulating the band gap. Theoretically, the optical cutoff frequency remains unchanged while the acoustic cutoff frequency shifts to a lower or higher frequency. A numerical simulation verifies the dispersion relationship and the effect of the amplitude-dependent signal filter. Based upon this, we design a device which contains both a linear periodic structure and a nonlinear periodic structure. When incident waves with the same, large amplitude pass through it from opposite directions, the output amplitude of the forward input is one order magnitude larger than that of the reverse input. Our devised, non-reciprocal device can potentially act as an acoustic diode (AD without an electrical circuit and frequency shifting. Our result represents a significant step forwards in the research of non-reciprocal wave manipulation.

  6. Estimating the period of a cyclic non-homogeneous Poisson process

    NARCIS (Netherlands)

    Belitser, E.; Andrade Serra, De P.J.; Zanten, van J.H.

    2013-01-01

    Motivated by applications of Poisson processes for modelling periodic time-varying phenomena, we study a semi-parametric estimator of the period of cyclic intensity function of a non-homogeneous Poisson process. There are no parametric assumptions on the intensity function which is treated as an

  7. Real-time method of powder diffraction for non-periodic and nearly periodic materials

    International Nuclear Information System (INIS)

    Egami, T.; Toby, B.H.; Dmowski, T.W.; Jorgensen, J.D.

    1989-12-01

    The use of high-energy neutrons from pulsed or hot sources allows the method of atomic pair distribution analysis to be applied to the structural determination of crystalline as well as amorphous solids. This method complements the standard crystallographic methods in studying non-periodic aspects of solids with or without long range order. 14 refs., 3 figs

  8. A MODIFIED GENETIC ALGORITHM FOR FINDING FUZZY SHORTEST PATHS IN UNCERTAIN NETWORKS

    Directory of Open Access Journals (Sweden)

    A. A. Heidari

    2016-06-01

    Full Text Available In realistic network analysis, there are several uncertainties in the measurements and computation of the arcs and vertices. These uncertainties should also be considered in realizing the shortest path problem (SPP due to the inherent fuzziness in the body of expert's knowledge. In this paper, we investigated the SPP under uncertainty to evaluate our modified genetic strategy. We improved the performance of genetic algorithm (GA to investigate a class of shortest path problems on networks with vague arc weights. The solutions of the uncertain SPP with considering fuzzy path lengths are examined and compared in detail. As a robust metaheuristic, GA algorithm is modified and evaluated to tackle the fuzzy SPP (FSPP with uncertain arcs. For this purpose, first, a dynamic operation is implemented to enrich the exploration/exploitation patterns of the conventional procedure and mitigate the premature convergence of GA technique. Then, the modified GA (MGA strategy is used to resolve the FSPP. The attained results of the proposed strategy are compared to those of GA with regard to the cost, quality of paths and CPU times. Numerical instances are provided to demonstrate the success of the proposed MGA-FSPP strategy in comparison with GA. The simulations affirm that not only the proposed technique can outperform GA, but also the qualities of the paths are effectively improved. The results clarify that the competence of the proposed GA is preferred in view of quality quantities. The results also demonstrate that the proposed method can efficiently be utilized to handle FSPP in uncertain networks.

  9. CO2 laser-inscribed low-cost, shortest-period long-period fibre ...

    Indian Academy of Sciences (India)

    2014-02-07

    up. Strain sensitivity of 1.77 dB/mε has been obtained for attenuation band corresponding to the turnaround point mode. TAP operation of LPG facilitates intensity-based detection using simple optical power meter instead.

  10. Modeling leukocyte-leukocyte non-contact interactions in a lymph node.

    Directory of Open Access Journals (Sweden)

    Nicola Gritti

    Full Text Available The interaction among leukocytes is at the basis of the innate and adaptive immune-response and it is largely ascribed to direct cell-cell contacts. However, the exchange of a number of chemical stimuli (chemokines allows also non-contact interaction during the immunological response. We want here to evaluate the extent of the effect of the non-contact interactions on the observed leukocyte-leukocyte kinematics and their interaction duration. To this aim we adopt a simplified mean field description inspired by the Keller-Segel chemotaxis model, of which we report an analytical solution suited for slowly varying sources of chemokines. Since our focus is on the non-contact interactions, leukocyte-leukocyte contact interactions are simulated only by means of a space dependent friction coefficient of the cells. The analytical solution of the Keller-Segel model is then taken as the basis of numerical simulations of interactions between leukocytes and their duration. The mean field interaction force that we derive has a time-space separable form and depends on the chemotaxis sensitivity parameter as well as on the chemokines diffusion coefficient and their degradation rate. All these parameters affect the distribution of the interaction durations. We draw a successful qualitative comparison between simulated data and sets of experimental data for DC-NK cells interaction duration and other kinematic parameters. Remarkably, the predicted percentage of the leukocyte-leukocyte interactions falls in the experimental range and depends (~25% increase upon the chemotactic parameter indicating a non-negligible direct effect of the non-contact interaction on the leukocyte interactions.

  11. Modeling leukocyte-leukocyte non-contact interactions in a lymph node.

    Science.gov (United States)

    Gritti, Nicola; Caccia, Michele; Sironi, Laura; Collini, Maddalena; D'Alfonso, Laura; Granucci, Francesca; Zanoni, Ivan; Chirico, Giuseppe

    2013-01-01

    The interaction among leukocytes is at the basis of the innate and adaptive immune-response and it is largely ascribed to direct cell-cell contacts. However, the exchange of a number of chemical stimuli (chemokines) allows also non-contact interaction during the immunological response. We want here to evaluate the extent of the effect of the non-contact interactions on the observed leukocyte-leukocyte kinematics and their interaction duration. To this aim we adopt a simplified mean field description inspired by the Keller-Segel chemotaxis model, of which we report an analytical solution suited for slowly varying sources of chemokines. Since our focus is on the non-contact interactions, leukocyte-leukocyte contact interactions are simulated only by means of a space dependent friction coefficient of the cells. The analytical solution of the Keller-Segel model is then taken as the basis of numerical simulations of interactions between leukocytes and their duration. The mean field interaction force that we derive has a time-space separable form and depends on the chemotaxis sensitivity parameter as well as on the chemokines diffusion coefficient and their degradation rate. All these parameters affect the distribution of the interaction durations. We draw a successful qualitative comparison between simulated data and sets of experimental data for DC-NK cells interaction duration and other kinematic parameters. Remarkably, the predicted percentage of the leukocyte-leukocyte interactions falls in the experimental range and depends (~25% increase) upon the chemotactic parameter indicating a non-negligible direct effect of the non-contact interaction on the leukocyte interactions.

  12. Comment: Distinguishing Cohort Effects from Age*Period Effects on Non-Marital Fertility

    Science.gov (United States)

    Martin, Steve

    2009-01-01

    In the article "Cohort Effects on Non-marital Fertility," in this issue of "Social Forces," Jean Stockard employs a novel strategy for disentangling cohort, period, and age effects on the non-marital fertility ratio. In a model with fixed-effect controls for age and for time period, the author documents evidence for three cohort-specific factors…

  13. Computing paths and cycles in biological interaction graphs

    Directory of Open Access Journals (Sweden)

    von Kamp Axel

    2009-06-01

    Full Text Available Abstract Background Interaction graphs (signed directed graphs provide an important qualitative modeling approach for Systems Biology. They enable the analysis of causal relationships in cellular networks and can even be useful for predicting qualitative aspects of systems dynamics. Fundamental issues in the analysis of interaction graphs are the enumeration of paths and cycles (feedback loops and the calculation of shortest positive/negative paths. These computational problems have been discussed only to a minor extent in the context of Systems Biology and in particular the shortest signed paths problem requires algorithmic developments. Results We first review algorithms for the enumeration of paths and cycles and show that these algorithms are superior to a recently proposed enumeration approach based on elementary-modes computation. The main part of this work deals with the computation of shortest positive/negative paths, an NP-complete problem for which only very few algorithms are described in the literature. We propose extensions and several new algorithm variants for computing either exact results or approximations. Benchmarks with various concrete biological networks show that exact results can sometimes be obtained in networks with several hundred nodes. A class of even larger graphs can still be treated exactly by a new algorithm combining exhaustive and simple search strategies. For graphs, where the computation of exact solutions becomes time-consuming or infeasible, we devised an approximative algorithm with polynomial complexity. Strikingly, in realistic networks (where a comparison with exact results was possible this algorithm delivered results that are very close or equal to the exact values. This phenomenon can probably be attributed to the particular topology of cellular signaling and regulatory networks which contain a relatively low number of negative feedback loops. Conclusion The calculation of shortest positive

  14. Non-resonant terahertz field enhancement in periodically arranged nanoslits

    DEFF Research Database (Denmark)

    Novitsky, Andrey; Ivinskaya, Aliaksandra; Zalkovskij, Maksim

    2012-01-01

    We analyze ultra strong non-resonant field enhancement of THz field in periodic arrays of nanoslits cut in ultrathin metal films. The main feature of our approach is that the slit size and metal film thickness are several orders of magnitude smaller than the wavelength λ of the impinging radiatio...... by the microscopic Drude-Lorentz model taking into account retardation processes in the metal film and validated by the finite difference frequency domain method. We expect sensor and modulation applications of the predicted giant broadband field enhancement.......We analyze ultra strong non-resonant field enhancement of THz field in periodic arrays of nanoslits cut in ultrathin metal films. The main feature of our approach is that the slit size and metal film thickness are several orders of magnitude smaller than the wavelength λ of the impinging radiation...... approaches the THz wavelength but before entering the Raleigh-Wood anomaly, the field enhancement in nanoslit stays close to that in a single isolated slit, i.e., the well-known inversefrequency dependence. Both regimes are non-resonant and thus extremely broadband for P

  15. Effects of non-standard interactions in the MINOS experiment

    International Nuclear Information System (INIS)

    Blennow, Mattias; Ohlsson, Tommy; Skrotzki, Julian

    2008-01-01

    We investigate the effects of non-standard interactions on the determination of the neutrino oscillation parameters Δm 31 2 , θ 23 , and θ 13 in the MINOS experiment. We show that adding non-standard interactions to the analysis lead to an extension of the allowed parameter space to larger values of Δm 31 2 and smaller θ 23 , and basically removes all predictability for θ 13 . In addition, we discuss the sensitivities to the non-standard interaction parameters of the MINOS experiment alone. In particular, we examine the degeneracy between θ 13 and the non-standard interaction parameter ε eτ . We find that this degeneracy is responsible for the removal of the θ 13 predictability and that the possible bound on |ε eτ | is competitive with direct bounds only if a more stringent external bound on θ 13 is applied

  16. DISK-PLANETS INTERACTIONS AND THE DIVERSITY OF PERIOD RATIOS IN KEPLER'S MULTI-PLANETARY SYSTEMS

    International Nuclear Information System (INIS)

    Baruteau, Clement; Papaloizou, John C. B.

    2013-01-01

    The Kepler mission is dramatically increasing the number of planets known in multi-planetary systems. Many adjacent planets have orbital period ratios near resonant values, with a tendency to be larger than required for exact first-order mean-motion resonances. This feature has been shown to be a natural outcome of orbital circularization of resonant planetary pairs due to star-planet tidal interactions. However, this feature holds in multi-planetary systems with periods longer than 10 days, in which tidal circularization is unlikely to provide efficient divergent evolution of the planets' orbits to explain these orbital period ratios. Gravitational interactions between planets and their parent protoplanetary disk may instead provide efficient divergent evolution. For a planet pair embedded in a disk, we show that interactions between a planet and the wake of its companion can reverse convergent migration and significantly increase the period ratio from a near-resonant value. Divergent evolution due to wake-planet interactions is particularly efficient when at least one of the planets opens a partial gap around its orbit. This mechanism could help account for the diversity of period ratios in Kepler's multiple systems from super-Earth to sub-Jovian planets with periods greater than about 10 days. Diversity is also expected for pairs of planets massive enough to merge their gap. The efficiency of wake-planet interactions is then much reduced, but convergent migration may stall with a variety of period ratios depending on the density structure in the common gap. This is illustrated for the Kepler-46 system, for which we reproduce the period ratio of Kepler-46b and c

  17. Non-periodic molecular dynamics simulations of coarse grained lipid bilayer in water

    DEFF Research Database (Denmark)

    Kotsalis, E. M.; Hanasaki, I.; Walther, Jens Honore

    2010-01-01

    We present a multiscale algorithm that couples coarse grained molecular dynamics (CGMD) with continuum solver. The coupling requires the imposition of non-periodic boundary conditions on the coarse grained Molecular Dynamics which, when not properly enforced, may result in spurious fluctuations o...... in simulating more complex systems by performing a non-periodic Molecular Dynamics simulation of a DPPC lipid in liquid coarse grained water.......We present a multiscale algorithm that couples coarse grained molecular dynamics (CGMD) with continuum solver. The coupling requires the imposition of non-periodic boundary conditions on the coarse grained Molecular Dynamics which, when not properly enforced, may result in spurious fluctuations...... of the material properties of the system represented by CGMD. In this paper we extend a control algorithm originally developed for atomistic simulations [3], to conduct simulations involving coarse grained water molecules without periodic boundary conditions. We demonstrate the applicability of our method...

  18. A minimum resource neural network framework for solving multiconstraint shortest path problems.

    Science.gov (United States)

    Zhang, Junying; Zhao, Xiaoxue; He, Xiaotao

    2014-08-01

    Characterized by using minimum hard (structural) and soft (computational) resources, a novel parameter-free minimal resource neural network (MRNN) framework is proposed for solving a wide range of single-source shortest path (SP) problems for various graph types. The problems are the k-shortest time path problems with any combination of three constraints: time, hop, and label constraints, and the graphs can be directed, undirected, or bidirected with symmetric and/or asymmetric traversal time, which can be real and time dependent. Isomorphic to the graph where the SP is to be sought, the network is activated by generating autowave at source neuron and the autowave travels automatically along the paths with the speed of a hop in an iteration. Properties of the network are studied, algorithms are presented, and computation complexity is analyzed. The framework guarantees globally optimal solutions of a series of problems during the iteration process of the network, which provides insight into why even the SP is still too long to be satisfied. The network facilitates very large scale integrated circuit implementation and adapt to very large scale problems due to its massively parallel processing and minimum resource utilization. When implemented in a sequentially processing computer, experiments on synthetic graphs, road maps of cities of the USA, and vehicle routing with time windows indicate that the MRNN is especially efficient for large scale sparse graphs and even dense graphs with some constraints, e.g., the CPU time taken and the iteration number used for the road maps of cities of the USA is even less than  ∼ 2% and 0.5% that of the Dijkstra's algorithm.

  19. Public-Key Encryption with Non-interactive Opening

    DEFF Research Database (Denmark)

    Damgård, Ivan Bjerre; Hofheinz, Dennis; Kiltz, Eike

    2008-01-01

    We formally define the primitive of public-key encryption with non-interactive opening (PKENO), where the receiver of a ciphertext C can, convincingly and without interaction, reveal what the result was of decrypting C, without compromising the scheme’s security. This has numerous applications...

  20. Plasma heating by non-linear wave-Plasma interaction | Echi ...

    African Journals Online (AJOL)

    We simulate the non-linear interaction of waves with magnetized tritium plasma with the aim of determining the parameter values that characterize the response of the plasma. The wave-plasma interaction has a non-conservative Hamiltonian description. The resulting system of Hamilton's equations is integrated numerically ...

  1. Alignment of non-covalent interactions at protein-protein interfaces.

    Directory of Open Access Journals (Sweden)

    Hongbo Zhu

    Full Text Available BACKGROUND: The study and comparison of protein-protein interfaces is essential for the understanding of the mechanisms of interaction between proteins. While there are many methods for comparing protein structures and protein binding sites, so far no methods have been reported for comparing the geometry of non-covalent interactions occurring at protein-protein interfaces. METHODOLOGY/PRINCIPAL FINDINGS: Here we present a method for aligning non-covalent interactions between different protein-protein interfaces. The method aligns the vector representations of van der Waals interactions and hydrogen bonds based on their geometry. The method has been applied to a dataset which comprises a variety of protein-protein interfaces. The alignments are consistent to a large extent with the results obtained using two other complementary approaches. In addition, we apply the method to three examples of protein mimicry. The method successfully aligns respective interfaces and allows for recognizing conserved interface regions. CONCLUSIONS/SIGNIFICANCE: The Galinter method has been validated in the comparison of interfaces in which homologous subunits are involved, including cases of mimicry. The method is also applicable to comparing interfaces involving non-peptidic compounds. Galinter assists users in identifying local interface regions with similar patterns of non-covalent interactions. This is particularly relevant to the investigation of the molecular basis of interaction mimicry.

  2. Non-periodic one-dimensional ideal conductors and integrable turbulence

    Energy Technology Data Exchange (ETDEWEB)

    Zakharov, Dmitry V. [Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, NY, 10012 (United States); Zakharov, Vladimir E. [Department of Mathematics, University of Arizona, Tucson, AZ, 85791 (United States); Dyachenko, Sergey A., E-mail: sdyachen@math.uiuc.edu [Department of Mathematics, University of Illinois, Urbana-Champaign, IL, 61801 (United States)

    2016-12-01

    Highlights: • An efficient procedure for construction of non-periodic, non-vanishing reflectionless potentials is presented. • The analytical procedure is reinforced by numerical simulation that presents some of these potentials. • The present work is a key ingredient for the study of integrable turbulence and statistical description of “solitonic gas”. - Abstract: To relate the motion of a quantum particle to the properties of the potential is a fundamental problem of physics, which is far from being solved. Can a medium with a potential which is neither periodic nor quasi-periodic be a conductor? That question seems to have been never addressed, despite being both interesting and having practical importance. Here we propose a new approach to the spectral problem of the one-dimensional Schrödinger operator with a bounded potential. We construct a wide class of potentials having a spectrum consisting of the positive semiaxis and finitely many bands on the negative semiaxis. These potentials, which we call primitive, are reflectionless for positive energy and in general are neither periodic nor quasi-periodic. Moreover, they can be stochastic, and yet allow ballistic transport, and thus describe one-dimensional ideal conductors. Primitive potentials also generate a new class of solutions of the KdV hierarchy. Stochastic primitive potentials describe integrable turbulence, which is important for hydrodynamics and nonlinear optics. We construct the potentials by numerically solving a system of singular integral equations. We hypothesize that finite-gap potentials are a subclass of primitive potentials, and prove this in the case of one-gap potentials.

  3. Storing quantum information in XXZ spin rings with periodically time-controlled interactions

    International Nuclear Information System (INIS)

    Giampaolo, S M; Illuminati, F; Mazzarella, G

    2005-01-01

    We introduce a general scheme to realize massive quantum memories in simple systems of interacting qubits. Such systems are described by spin rings with XXZ intersite couplings of suitably time-periodically controlled amplitudes. We show that initially localized excitations undergo perfect periodic revivals, allowing for the simultaneous storage of arbitrary sets of different local states. This novel approach to the problem of storing quantum information hints at a new way to control and suppress the effect of decoherence on a quantum computer realized in a system with nonvanishing interactions between the constituent qubits

  4. Storing quantum information in XXZ spin rings with periodically time-controlled interactions

    Energy Technology Data Exchange (ETDEWEB)

    Giampaolo, S M; Illuminati, F; Mazzarella, G [Dipartimento di Fisica ' E. R. Caianiello' , Universita di Salerno, INFM UdR di Salerno, INFN Sezione di Napoli, Gruppo Collegato di Salerno, Via S. Allende, 84081 Baronissi, SA (Italy)

    2005-10-01

    We introduce a general scheme to realize massive quantum memories in simple systems of interacting qubits. Such systems are described by spin rings with XXZ intersite couplings of suitably time-periodically controlled amplitudes. We show that initially localized excitations undergo perfect periodic revivals, allowing for the simultaneous storage of arbitrary sets of different local states. This novel approach to the problem of storing quantum information hints at a new way to control and suppress the effect of decoherence on a quantum computer realized in a system with nonvanishing interactions between the constituent qubits.

  5. Tidally distorted exoplanets: Density corrections for short-period hot-Jupiters based solely on observable parameters

    Energy Technology Data Exchange (ETDEWEB)

    Burton, J. R.; Watson, C. A.; Fitzsimmons, A.; Moulds, V. [Astrophysics Research Centre, Queen' s University Belfast, Belfast BT7 1NN (United Kingdom); Pollacco, D.; Wheatley, P. J. [Department of Physics and Astronomy, University of Warwick, Coventry CV4 7AL (United Kingdom); Littlefair, S. P., E-mail: jburton04@qub.ac.uk [Department of Physics and Astronomy, University of Sheffield, Sheffield S3 7RH (United Kingdom)

    2014-07-10

    The close proximity of short-period hot-Jupiters to their parent star means they are subject to extreme tidal forces. This has a profound effect on their structure and, as a result, density measurements that assume that the planet is spherical can be incorrect. We have simulated the tidally distorted surface for 34 known short-period hot-Jupiters, assuming surfaces of constant gravitational equipotential for the planet, and the resulting densities have been calculated based only on observed parameters of the exoplanet systems. Comparing these results to the density values, assuming the planets are spherical, shows that there is an appreciable change in the measured density for planets with very short periods (typically less than two days). For one of the shortest-period systems, WASP-19b, we determine a decrease in bulk density of 12% from the spherical case and, for the majority of systems in this study, this value is in the range of 1%-5%. On the other hand, we also find cases where the distortion is negligible (relative to the measurement errors on the planetary parameters) even in the cases of some very short period systems, depending on the mass ratio and planetary radius. For high-density gas planets requiring apparently anomalously large core masses, density corrections due to tidal deformation could become important for the shortest-period systems.

  6. Technical note: Quantification of neurocranial shape variation using the shortest paths connecting pairs of anatomical landmarks.

    Science.gov (United States)

    Morita, Yusuke; Ogihara, Naomichi; Kanai, Takashi; Suzuki, Hiromasa

    2013-08-01

    Three-dimensional geometric morphometric techniques have been widely used in quantitative comparisons of craniofacial morphology in humans and nonhuman primates. However, few anatomical landmarks can actually be defined on the neurocranium. In this study, an alternative method is proposed for defining semi-landmarks on neurocranial surfaces for use in detailed analysis of cranial shape. Specifically, midsagittal, nuchal, and temporal lines were approximated using Bezier curves and equally spaced points along each of the curves were defined as semi-landmarks. The shortest paths connecting pairs of anatomical landmarks as well as semi-landmarks were then calculated in order to represent the surface morphology between landmarks using equally spaced points along the paths. To evaluate the efficacy of this method, the previously outlined technique was used in morphological analysis of sexual dimorphism in modern Japanese crania. The study sample comprised 22 specimens that were used to generate 110 anatomical semi-landmarks, which were used in geometric morphometric analysis. Although variations due to sexual dimorphism in human crania are very small, differences could be identified using the proposed landmark placement, which demonstrated the efficacy of the proposed method. Copyright © 2013 Wiley Periodicals, Inc.

  7. Non-separable pairing interaction kernels applied to superconducting cuprates

    International Nuclear Information System (INIS)

    Haley, Stephen B.; Fink, Herman J.

    2014-01-01

    Highlights: • Non-separable interaction kernels with weak interactions produces HTS. • A probabilistic approach is used in filling the electronic states in the unit cell. • A set of coupled equations is derived which describes the energy gap. • SC properties of separable with non-separable interactions are compared. • There is agreement with measured properties of the SC and normal states. - Abstract: A pairing Hamiltonian H(Γ) with a non-separable interaction kernel Γ produces HTS for relatively weak interactions. The doping and temperature dependence of Γ(x,T) and the chemical potential μ(x) is determined by a probabilistic filling of the electronic states in the cuprate unit cell. A diverse set of HTS and normal state properties is examined, including the SC phase transition boundary T C (x), SC gap Δ(x,T), entropy S(x,T), specific heat C(x,T), and spin susceptibility χ s (x,T). Detailed x,T agreement with cuprate experiment is obtained for all properties

  8. Particle swarm optimization for determining shortest distance to voltage collapse

    Energy Technology Data Exchange (ETDEWEB)

    Arya, L.D.; Choube, S.C. [Electrical Engineering Department, S.G.S.I.T.S. Indore, MP 452 003 (India); Shrivastava, M. [Electrical Engineering Department, Government Engineering College Ujjain, MP 456 010 (India); Kothari, D.P. [Centre for Energy Studies, Indian Institute of Technology, Delhi (India)

    2007-12-15

    This paper describes an algorithm for computing shortest distance to voltage collapse or determination of CSNBP using PSO technique. A direction along CSNBP gives conservative results from voltage security view point. This information is useful to the operator to steer the system away from this point by taking corrective actions. The distance to a closest bifurcation is a minimum of the loadability given a slack bus or participation factors for increasing generation as the load increases. CSNBP determination has been formulated as an optimization problem to be used in PSO technique. PSO is a new evolutionary algorithm (EA) which is population based inspired by the social behavior of animals such as fish schooling and birds flocking. It can handle optimization problems with any complexity since mechanization is simple with few parameters to be tuned. The developed algorithm has been implemented on two standard test systems. (author)

  9. Interactions between non-physician clinicians and industry: a systematic review.

    Directory of Open Access Journals (Sweden)

    Quinn Grundy

    2013-11-01

    Full Text Available BACKGROUND: With increasing restrictions placed on physician-industry interactions, industry marketing may target other health professionals. Recent health policy developments confer even greater importance on the decision making of non-physician clinicians. The purpose of this systematic review is to examine the types and implications of non-physician clinician-industry interactions in clinical practice. METHODS AND FINDINGS: We searched MEDLINE and Web of Science from January 1, 1946, through June 24, 2013, according to PRISMA guidelines. Non-physician clinicians eligible for inclusion were: Registered Nurses, nurse prescribers, Physician Assistants, pharmacists, dieticians, and physical or occupational therapists; trainee samples were excluded. Fifteen studies met inclusion criteria. Data were synthesized qualitatively into eight outcome domains: nature and frequency of industry interactions; attitudes toward industry; perceived ethical acceptability of interactions; perceived marketing influence; perceived reliability of industry information; preparation for industry interactions; reactions to industry relations policy; and management of industry interactions. Non-physician clinicians reported interacting with the pharmaceutical and infant formula industries. Clinicians across disciplines met with pharmaceutical representatives regularly and relied on them for practice information. Clinicians frequently received industry "information," attended sponsored "education," and acted as distributors for similar materials targeted at patients. Clinicians generally regarded this as an ethical use of industry resources, and felt they could detect "promotion" while benefiting from industry "information." Free samples were among the most approved and common ways that clinicians interacted with industry. Included studies were observational and of varying methodological rigor; thus, these findings may not be generalizable. This review is, however, the

  10. Interactions between non-physician clinicians and industry: a systematic review.

    Science.gov (United States)

    Grundy, Quinn; Bero, Lisa; Malone, Ruth

    2013-11-01

    With increasing restrictions placed on physician-industry interactions, industry marketing may target other health professionals. Recent health policy developments confer even greater importance on the decision making of non-physician clinicians. The purpose of this systematic review is to examine the types and implications of non-physician clinician-industry interactions in clinical practice. We searched MEDLINE and Web of Science from January 1, 1946, through June 24, 2013, according to PRISMA guidelines. Non-physician clinicians eligible for inclusion were: Registered Nurses, nurse prescribers, Physician Assistants, pharmacists, dieticians, and physical or occupational therapists; trainee samples were excluded. Fifteen studies met inclusion criteria. Data were synthesized qualitatively into eight outcome domains: nature and frequency of industry interactions; attitudes toward industry; perceived ethical acceptability of interactions; perceived marketing influence; perceived reliability of industry information; preparation for industry interactions; reactions to industry relations policy; and management of industry interactions. Non-physician clinicians reported interacting with the pharmaceutical and infant formula industries. Clinicians across disciplines met with pharmaceutical representatives regularly and relied on them for practice information. Clinicians frequently received industry "information," attended sponsored "education," and acted as distributors for similar materials targeted at patients. Clinicians generally regarded this as an ethical use of industry resources, and felt they could detect "promotion" while benefiting from industry "information." Free samples were among the most approved and common ways that clinicians interacted with industry. Included studies were observational and of varying methodological rigor; thus, these findings may not be generalizable. This review is, however, the first to our knowledge to provide a descriptive analysis

  11. Special Features In Turbulent Mixing. Comparison between Periodic and Non Periodic Case

    Directory of Open Access Journals (Sweden)

    Mihai Costescu

    2006-12-01

    Full Text Available After hundreds of years of stability study, the problems of flow kinematics are far from complete solving. A modern theory appears in this field: the mixing theory. Its mathematical methods and techniques developed the significant relation between turbulence and chaos. The turbulence is an important feature of dynamic systems with few freedom degrees, the so-called far from equilibrium systems. These are widespread between the models of excitable media.Studying a mixing for a flow implies the analysis of successive stretching and folding phenomena for its particles, the influence of parameters and initial conditions. In the previous works, the study of the 3D non-periodic models exhibited a quite complicated behavior, involving some significant events - the so-called rare events. The variation of parameters had a great influence on the length and surface deformations. The 2D (periodic case is simpler, but significant events can also issue for irrational values of the length and surface versors, as was the situation in 3D case.The comparison between 2D and 3D case revealed interesting properties; therefore a modified 2D (periodic model is tested. The numerical simulations were realized in MapleVI, for searching special mathematical events. Continuing this work both from analytical and numeric standpoint would relieve useful properties for the turbulent mixing. A proximal target is to test some special functions for the periodic model, and to study the behavior of the structures realized by the model.

  12. The Properties of Long Period Variables in the LMC from MACHO

    Energy Technology Data Exchange (ETDEWEB)

    Fraser, O J; Hawley, S L; Cook, K H

    2008-05-06

    We present a new analysis of the long period variables in the Large Magellanic Cloud from the MACHO Variable Star Catalog. Three-quarters of our sample of evolved, variable stars have periodic light curves. We characterize the stars in our sample using the multiple periods found in their frequency spectra. Additionally, we use single-epoch 2MASS measurements to construct the average infrared light curves for different groups of these stars. Comparison with evolutionary models shows that stars on the RGB or the Early AGB often show non-periodic variability, but begin to pulsate with periods on the two shortest period-luminosity sequences (1 & 2) when they brighten to K{sub s} {approx} 13. The stars on the Thermally Pulsing AGB are more likely to pulsate with longer periods that lie on the next two P-L sequences (3 & 4), including the sequence associated with the Miras in the LMC. The Petersen diagram and its variants show that multi-periodic stars on each pair of these sequences (3 & 4, and 1 & 2), typically pulsate with periods associated only with that pair. The periods in these multi-periodic stars become longer and stronger as the star evolves. We further constrain the mechanism behind the long secondary periods (LSPs) seen in half of our sample, and find that there is a close match between the luminosity functions of the LSP stars and all of the stars in our sample, and that these star's pulsation amplitudes are relatively wavelength independent. Although this is characteristic of stellar multiplicity, the large number of these variables is problematic for that explanation.

  13. Geometrical Aspects of non-gravitational interactions

    OpenAIRE

    Roldan, Omar; Barros Jr, C. C.

    2016-01-01

    In this work we look for a geometric description of non-gravitational forces. The basic ideas are proposed studying the interaction between a punctual particle and an electromagnetic external field. For this purpose, we introduce the concept of proper space-time, that allow us to describe this interaction in a way analogous to the one that the general relativity theory does for gravitation. The field equations that define this geometry are similar to the Einstein's equations, where in general...

  14. STABLE STATIONARY STATES OF NON-LOCAL INTERACTION EQUATIONS

    KAUST Repository

    FELLNER, KLEMENS

    2010-12-01

    In this paper, we are interested in the large-time behaviour of a solution to a non-local interaction equation, where a density of particles/individuals evolves subject to an interaction potential and an external potential. It is known that for regular interaction potentials, stable stationary states of these equations are generically finite sums of Dirac masses. For a finite sum of Dirac masses, we give (i) a condition to be a stationary state, (ii) two necessary conditions of linear stability w.r.t. shifts and reallocations of individual Dirac masses, and (iii) show that these linear stability conditions imply local non-linear stability. Finally, we show that for regular repulsive interaction potential Wε converging to a singular repulsive interaction potential W, the Dirac-type stationary states ρ̄ ε approximate weakly a unique stationary state ρ̄ ∈ L∞. We illustrate our results with numerical examples. © 2010 World Scientific Publishing Company.

  15. Suppressing non-periodically repeating disturbances in mechanical servo systems

    NARCIS (Netherlands)

    Tousain, R.L.; Boissy, J.C.; Norg, M.L.; Steinbuch, M.; Bosgra, O.H.

    1998-01-01

    Non-periodically repeating (NPR) disturbances are fixed-shape disturbances that occur randomly in time. We can provide a control system with the capability to suppress this type of disturbance by adding in parallel to the input of the nominal feedback controller a learning look-up-table based

  16. Shortest loops are pacemakers in random networks of electrically coupled axons

    Directory of Open Access Journals (Sweden)

    Nikita eVladimirov

    2012-04-01

    Full Text Available High-frequency oscillations (HFOs are an important part of brain activity in health and disease. However, their origins remain obscure and controversial. One possible mechanism depends on the presence of sparsely distributed gap junctions that electrically couple the axons of principal cells. A plexus of electrically coupled axons is modeled as a random network with bidirectional connections between its nodes. Under certain conditions the network can demonstrate one of two types of oscillatory activity. Type I oscillations (100-200 Hz are predicted to be caused by spontaneously spiking axons in a network with strong (high-conductance gap junctions. Type II oscillations (200-300 Hz require no spontaneous spiking and relatively weak (low-conductance gap junctions, across which spike propagation failures occur. The type II oscillations are reentrant and self-sustained. Here we examine what determines the frequency of type II oscillations. Using simulations we show that the distribution of loop lengths is the key factor for determining frequency in type II network oscillations. We first analyze spike failure between two electrically coupled cells using a model of anatomically reconstructed CA1 pyramidal neuron. Then network oscillations are studied by a cellular automaton model with random network connectivity, in which we control loop statistics. We show that oscillation periods can be predicted from the network's loop statistics. The shortest loop, around which a spike can travel, is the most likely pacemaker candidate.The principle of one loop as a pacemaker is remarkable, because random networks contain a large number of loops juxtaposed and superimposed, and their number rapidly grows with network size. This principle allows us to predict the frequency of oscillations from network connectivity and visa versa. We finally propose that type I oscillations may correspond to ripples, while type II oscillations correspond to so-called fast ripples.

  17. Temporal and Periodic Variations of Sunspot Counts in Flaring and Non-Flaring Active Regions

    Science.gov (United States)

    Kilcik, A.; Yurchyshyn, V.; Donmez, B.; Obridko, V. N.; Ozguc, A.; Rozelot, J. P.

    2018-04-01

    We analyzed temporal and periodic variations of sunspot counts (SSCs) in flaring (C-, M-, or X-class flares), and non-flaring active regions (ARs) for nearly three solar cycles (1986 through 2016). Our main findings are as follows: i) temporal variations of monthly means of the daily total SSCs in flaring and non-flaring ARs behave differently during a solar cycle and the behavior varies from one cycle to another; during Solar Cycle 23 temporal SSC profiles of non-flaring ARs are wider than those of flaring ARs, while they are almost the same during Solar Cycle 22 and the current Cycle 24. The SSC profiles show a multi-peak structure and the second peak of flaring ARs dominates the current Cycle 24, while the difference between peaks is less pronounced during Solar Cycles 22 and 23. The first and second SSC peaks of non-flaring ARs have comparable magnitude in the current solar cycle, while the first peak is nearly absent in the case of the flaring ARs of the same cycle. ii) Periodic variations observed in the SSCs profiles of flaring and non-flaring ARs derived from the multi-taper method (MTM) spectrum and wavelet scalograms are quite different as well, and they vary from one solar cycle to another. The largest detected period in flaring ARs is 113± 1.6 days while we detected much longer periodicities (327± 13, 312 ± 11, and 256± 8 days) in the non-flaring AR profiles. No meaningful periodicities were detected in the MTM spectrum of flaring ARs exceeding 55± 0.7 days during Solar Cycles 22 and 24, while a 113± 1.3 days period was detected in flaring ARs of Solar Cycle 23. For the non-flaring ARs the largest detected period was only 31± 0.2 days for Cycle 22 and 72± 1.3 days for the current Cycle 24, while the largest measured period was 327± 13 days during Solar Cycle 23.

  18. Effects of non-structural components and soil-structure interaction on the seismic response of framed structures

    Science.gov (United States)

    Ditommaso, Rocco; Auletta, Gianluca; Iacovino, Chiara; Nigro, Antonella; Carlo Ponzo, Felice

    2017-04-01

    In this paper, several nonlinear numerical models of reinforced concrete framed structures have been defined in order to evaluate the effects of non-structural elements and soil-structure interaction on the elastic dynamic behaviour of buildings. In the last few years, many and various studies have highlighted the significant effects derived from the interaction between structural and non-structural components on the main dynamic characteristics of a building. Usually, structural and non-structural elements act together, adding both masses and stiffness. The presence of infill panels is generally neglected in the design process of structural elements, although these elements can significantly increase the lateral stiffness of a structure leading to a modification in the dynamic properties. Particularly, at the Damage Limit State (where an elastic behaviour is expected), soil-structure interaction effects and non-structural elements may further affect the elastic natural period of buildings, changing the spectral accelerations compared with those provided by seismic codes in case of static analyses. In this work, a parametric study has been performed in order to evaluate the elastic fundamental period of vibration of buildings as a function of structural morphology (height, plan area, ratio between plan dimensions), infills presence and distribution and soil characteristics. Acknowledgements This study was partially funded by the Italian Department of Civil Protection within the project DPC-RELUIS 2016 - RS4 ''Seismic observatory of structures and health monitoring'' and by the "Centre of Integrated Geomorphology for the Mediterranean Area - CGIAM" within the Framework Agreement with the University of Basilicata "Study, Research and Experimentation in the Field of Analysis and Monitoring of Seismic Vulnerability of Strategic and Relevant Buildings for the purposes of Civil Protection and Development of Innovative Strategies of Seismic Reinforcement".

  19. Norm of nuclear weapons non-use and deterrence: interaction of the conceptions in case of usa

    OpenAIRE

    Bladaitė, Neringa

    2016-01-01

    Norm of Nuclear Weapons Non-use and Deterrence: Interaction of the Conceptions in Case of USA The problem that is analyzed in this master thesis is formed according the paradox. Although, US is thought to be the county that maintains norm of non-use, in the practice US forms the strategy according nuclear deterrence. The object of this master thesis is nuclear weapons posture of US during the period of 2009-2015. The main aim of this thesis is to explore posture of US nuclear weapons use base...

  20. Non-Unitarity, sterile neutrinos, and Non-Standard neutrino Interactions

    CERN Document Server

    Blennow, Mattias; Fernandez-Martinez, Enrique; Hernandez-Garcia, Josu; Lopez-Pavon, Jacobo

    2017-04-27

    The simplest Standard Model extension to explain neutrino masses involves the addition of right-handed neutrinos. At some level, this extension will impact neutrino oscillation searches. In this work we explore the differences and similarities between the case in which these neutrinos are kinematically accessible (sterile neutrinos) or not (mixing matrix non-unitarity). We clarify apparent inconsistencies in the present literature when using different parametrizations to describe these effects and recast both limits in the popular neutrino non-standard interaction (NSI) formal- ism. We find that, in the limit in which sterile oscillations are averaged out at the near detector, their effects at the far detector coincide with non-unitarity at leading order, even in presence of a matter potential. We also summarize the present bounds existing in both limits and compare them with the expected sensitivities of near-future facilities taking the DUNE proposal as a bench- mark. We conclude that non-unitarity effects ...

  1. Effect of interactions for one-dimensional asymmetric exclusion processes under periodic and bath-adapted coupling environment

    Science.gov (United States)

    Midha, Tripti; Kolomeisky, Anatoly B.; Gupta, Arvind Kumar

    2018-04-01

    Stimulated by the effect of the nearest neighbor interactions in vehicular traffic and motor proteins, we study a 1D driven lattice gas model, in which the nearest neighbor particle interactions are taken in accordance with the thermodynamic concepts. The non-equilibrium steady-state properties of the system are analyzed under both open and periodic boundary conditions using a combination of cluster mean-field analysis and Monte Carlo simulations. Interestingly, the fundamental diagram of current versus density shows a complex behavior with a unimodal dependence for attractions and weak repulsions that turns into the bimodal behavior for stronger repulsive interactions. Specific details of system-reservoir coupling for the open system have a strong effect on the stationary phases. We produce the steady-state phase diagrams for the bulk-adapted coupling to the reservoir using the minimum and maximum current principles. The strength and nature of interaction energy has a striking influence on the number of stationary phases. We observe that interactions lead to correlations having a strong impact on the system dynamical properties. The correlation between any two sites decays exponentially as the distance between the sites increases. Moreover, they are found to be short-range for repulsions and long-range for attractions. Our results also suggest that repulsions and attractions asymmetrically modify the dynamics of interacting particles in exclusion processes.

  2. Positronium annihilation in liquids in the framework of non-local interaction

    International Nuclear Information System (INIS)

    Mukherjee, Tapas; Dutta, Dhanadeep

    2012-01-01

    In the bubble model of ortho positronium (o-Ps) annihilation in liquid the origin of the trapping of o-Ps is the electron-exchange repulsive interaction between the electron of o-Ps and the electron of the medium. The corresponding effective interaction is non-local in nature. However, in the prevalent bubble model, this effective interaction is usually treated as local (model) potential (sharp or smooth). In the present study, we have taken an approach to consider this trapping interaction as non-local in nature, which is included through a model separable non-local function to tackle the problem in analytically solvable manner. The analytical calculations show that this non-local interaction effectively acts as a gauge potential in the energy of the Ps atom in parameter (bubble radius) space. The computed bubble variables obtained using experimental Ps annihilation data are shown. A comparison between the present data with the calculated results using prevalent bubble model has been presented. Discussions have been made on the input parameter dependencies of the computed data. - Highlights: ► Bubble model has been modified by considering positronium-atom non-local interaction. ► No straight forward correlation between bubble size and effective potential is observed. ► Non-local potential acts as a guage potential.

  3. ACL2 Meets the GPU: Formalizing a CUDA-based Parallelizable All-Pairs Shortest Path Algorithm in ACL2

    Directory of Open Access Journals (Sweden)

    David S. Hardin

    2013-04-01

    Full Text Available As Graphics Processing Units (GPUs have gained in capability and GPU development environments have matured, developers are increasingly turning to the GPU to off-load the main host CPU of numerically-intensive, parallelizable computations. Modern GPUs feature hundreds of cores, and offer programming niceties such as double-precision floating point, and even limited recursion. This shift from CPU to GPU, however, raises the question: how do we know that these new GPU-based algorithms are correct? In order to explore this new verification frontier, we formalized a parallelizable all-pairs shortest path (APSP algorithm for weighted graphs, originally coded in NVIDIA's CUDA language, in ACL2. The ACL2 specification is written using a single-threaded object (stobj and tail recursion, as the stobj/tail recursion combination yields the most straightforward translation from imperative programming languages, as well as efficient, scalable executable specifications within ACL2 itself. The ACL2 version of the APSP algorithm can process millions of vertices and edges with little to no garbage generation, and executes at one-sixth the speed of a host-based version of APSP coded in C – a very respectable result for a theorem prover. In addition to formalizing the APSP algorithm (which uses Dijkstra's shortest path algorithm at its core, we have also provided capability that the original APSP code lacked, namely shortest path recovery. Path recovery is accomplished using a secondary ACL2 stobj implementing a LIFO stack, which is proven correct. To conclude the experiment, we ported the ACL2 version of the APSP kernels back to C, resulting in a less than 5% slowdown, and also performed a partial back-port to CUDA, which, surprisingly, yielded a slight performance increase.

  4. Comparison of the efficiency of two algorithms which solve the shortest path problem with an emotional agent

    Directory of Open Access Journals (Sweden)

    Petruseva Silvana

    2006-01-01

    Full Text Available This paper discusses the comparison of the efficiency of two algorithms, by estimation of their complexity. For solving the problem, the Neural Network Crossbar Adaptive Array (NN-CAA is used as the agent architecture, implementing a model of an emotion. The problem discussed is how to find the shortest path in an environment with n states. The domains concerned are environments with n states, one of which is the starting state, one is the goal state, and some states are undesirable and they should be avoided. It is obtained that finding one path (one solution is efficient, i.e. in polynomial time by both algorithms. One of the algorithms is faster than the other only in the multiplicative constant, and it shows a step forward toward the optimality of the learning process. However, finding the optimal solution (the shortest path by both algorithms is in exponential time which is asserted by two theorems. It might be concluded that the concept of subgoal is one step forward toward the optimality of the process of the agent learning. Yet, it should be explored further on, in order to obtain an efficient, polynomial algorithm.

  5. Exact periodic waves and their interactions for the (2+1 ...

    Indian Academy of Sciences (India)

    The interaction properties of the periodic waves are in- vestigated numerically and found to be nonelastic. The long wave limit yields some new types of solitary wave solutions. Especially the dromion and the solitoff solutions obtained in this paper possess new types of solution structures which are quite different from the.

  6. ECG-gated interventional cardiac reconstruction for non-periodic motion.

    Science.gov (United States)

    Rohkohl, Christopher; Lauritsch, Günter; Biller, Lisa; Hornegger, Joachim

    2010-01-01

    The 3-D reconstruction of cardiac vasculature using C-arm CT is an active and challenging field of research. In interventional environments patients often do have arrhythmic heart signals or cannot hold breath during the complete data acquisition. This important group of patients cannot be reconstructed with current approaches that do strongly depend on a high degree of cardiac motion periodicity for working properly. In a last year's MICCAI contribution a first algorithm was presented that is able to estimate non-periodic 4-D motion patterns. However, to some degree that algorithm still depends on periodicity, as it requires a prior image which is obtained using a simple ECG-gated reconstruction. In this work we aim to provide a solution to this problem by developing a motion compensated ECG-gating algorithm. It is built upon a 4-D time-continuous affine motion model which is capable of compactly describing highly non-periodic motion patterns. A stochastic optimization scheme is derived which minimizes the error between the measured projection data and the forward projection of the motion compensated reconstruction. For evaluation, the algorithm is applied to 5 datasets of the left coronary arteries of patients that have ignored the breath hold command and/or had arrhythmic heart signals during the data acquisition. By applying the developed algorithm the average visibility of the vessel segments could be increased by 27%. The results show that the proposed algorithm provides excellent reconstruction quality in cases where classical approaches fail. The algorithm is highly parallelizable and a clinically feasible runtime of under 4 minutes is achieved using modern graphics card hardware.

  7. Solving fuzzy shortest path problem by genetic algorithm

    Science.gov (United States)

    Syarif, A.; Muludi, K.; Adrian, R.; Gen, M.

    2018-03-01

    Shortest Path Problem (SPP) is known as one of well-studied fields in the area Operations Research and Mathematical Optimization. It has been applied for many engineering and management designs. The objective is usually to determine path(s) in the network with minimum total cost or traveling time. In the past, the cost value for each arc was usually assigned or estimated as a deteministic value. For some specific real world applications, however, it is often difficult to determine the cost value properly. One way of handling such uncertainty in decision making is by introducing fuzzy approach. With this situation, it will become difficult to solve the problem optimally. This paper presents the investigations on the application of Genetic Algorithm (GA) to a new SPP model in which the cost values are represented as Triangular Fuzzy Number (TFN). We adopts the concept of ranking fuzzy numbers to determine how good the solutions. Here, by giving his/her degree value, the decision maker can determine the range of objective value. This would be very valuable for decision support system in the real world applications.Simulation experiments were carried out by modifying several test problems with 10-25 nodes. It is noted that the proposed approach is capable attaining a good solution with different degree of optimism for the tested problems.

  8. Spatial interaction creates period-doubling bifurcation and chaos of urbanization

    International Nuclear Information System (INIS)

    Chen Yanguang

    2009-01-01

    This paper provides a new way of looking at complicated dynamics of simple mathematical models. The complicated behavior of simple equations is one of the headstreams of chaos theory. However, a recent study based on dynamical equations of urbanization shows that there are still some undiscovered secrets behind the simple mathematical models such as logistic equation. The rural-urban interaction model can also display varied kinds of complicated dynamics, including period-doubling bifurcation and chaos. The two-dimension map of urbanization presents the same dynamics as that from the one-dimension logistic map. In theory, the logistic equation can be derived from the two-population interaction model. This seems to suggest that the complicated behavior of simple models results from interaction rather than pure intrinsic randomicity. In light of this idea, the classical predator-prey interaction model can be revised to explain the complex dynamics of logistic equation in physical and social sciences.

  9. Curtailing the dark side in non-standard neutrino interactions

    Energy Technology Data Exchange (ETDEWEB)

    Coloma, Pilar [Theoretical Physics Department, Fermi National Accelerator Laboratory,P.O. Box 500, Batavia, IL 60510 (United States); Denton, Peter B. [Theoretical Physics Department, Fermi National Accelerator Laboratory,P.O. Box 500, Batavia, IL 60510 (United States); Niels Bohr International Academy, University of Copenhagen, The Niels Bohr Institute,Blegdamsvej 17, DK-2100, Copenhagen (Denmark); Gonzalez-Garcia, M.C. [Departament de Fisíca Quàntica i Astrofísica and Institut de Ciencies del Cosmos,Universitat de Barcelona, Diagonal 647, E-08028 Barcelona (Spain); Institució Catalana de Recerca i Estudis Avançats (ICREA),Pg. Lluis Companys 23, 08010 Barcelona (Spain); C.N. Yang Institute for Theoretical Physics, Stony Brook University,Stony Brook, NY 11794-3840 (United States); Maltoni, Michele [Instituto de Física Teórica UAM/CSIC, Universidad Autónoma de Madrid,Calle de Nicolás Cabrera 13-15, Cantoblanco, E-28049 Madrid (Spain); Schwetz, Thomas [Institut für Kernphysik, Karlsruher Institut für Technologie (KIT), D-76021 Karlsruhe (Germany)

    2017-04-20

    In presence of non-standard neutrino interactions the neutrino flavor evolution equation is affected by a degeneracy which leads to the so-called LMA-Dark solution. It requires a solar mixing angle in the second octant and implies an ambiguity in the neutrino mass ordering. Non-oscillation experiments are required to break this degeneracy. We perform a combined analysis of data from oscillation experiments with the neutrino scattering experiments CHARM and NuTeV. We find that the degeneracy can be lifted if the non-standard neutrino interactions take place with down quarks, but it remains for up quarks. However, CHARM and NuTeV constraints apply only if the new interactions take place through mediators not much lighter than the electroweak scale. For light mediators we consider the possibility to resolve the degeneracy by using data from future coherent neutrino-nucleus scattering experiments. We find that, for an experiment using a stopped-pion neutrino source, the LMA-Dark degeneracy will either be resolved, or the presence of new interactions in the neutrino sector will be established with high significance.

  10. Non interacting control by measurement feedback

    NARCIS (Netherlands)

    Woude, van der J.W.

    1987-01-01

    In this paper we shall solve the problem of non interacting control by measurement feedback for systems that in addition to a control input and a measurement output have two exogenous inputs and two exogenous outputs. That is, we shall derive necessary and sufficient conditions that can actually be

  11. A Meta-study of musicians' non-verbal interaction

    DEFF Research Database (Denmark)

    Jensen, Karl Kristoffer; Marchetti, Emanuela

    2010-01-01

    interruptions. Hence, despite the fact that the skill to engage in a non-verbal interaction is described as tacit knowledge, it is fundamental for both musicians and teachers (Davidson and Good 2002). Typical observed non-verbal cues are for example: physical gestures, modulations of sound, steady eye contact...

  12. Numerical study of two disks settling in an Oldroyd-B fluid: From periodic interaction to chaining

    Science.gov (United States)

    Pan, Tsorng-Whay; Glowinski, Roland

    2017-12-01

    In this article, we present a numerical study of the dynamics of two disks sedimenting in a narrow vertical channel filled with an Oldroyd-B fluid. Two kinds of particle dynamics are observed: (i) a periodic interaction between the two disks, and (ii) the formation of a two-disk chain. For the periodic interaction of the two disks, two different motions are observed: (a) the two disks stay far apart and interact periodically, and (b) the two disks interact closely and then far apart in a periodic way, like the drafting, kissing, and tumbling of two disks sedimenting in a Newtonian fluid, due to a weak elastic force. Concerning the formation of a two-disk chain occurring at higher values of the elasticity number, either a tilted chain or a vertical chain is observed. Our simulations show that, as expected, the values of the elasticity and Mach numbers are the determining factors concerning the particle chain formation and its orientation.

  13. Comparative study on collaborative interaction in non-immersive and immersive systems

    Science.gov (United States)

    Shahab, Qonita M.; Kwon, Yong-Moo; Ko, Heedong; Mayangsari, Maria N.; Yamasaki, Shoko; Nishino, Hiroaki

    2007-09-01

    This research studies the Virtual Reality simulation for collaborative interaction so that different people from different places can interact with one object concurrently. Our focus is the real-time handling of inputs from multiple users, where object's behavior is determined by the combination of the multiple inputs. Issues addressed in this research are: 1) The effects of using haptics on a collaborative interaction, 2) The possibilities of collaboration between users from different environments. We conducted user tests on our system in several cases: 1) Comparison between non-haptics and haptics collaborative interaction over LAN, 2) Comparison between non-haptics and haptics collaborative interaction over Internet, and 3) Analysis of collaborative interaction between non-immersive and immersive display environments. The case studies are the interaction of users in two cases: collaborative authoring of a 3D model by two users, and collaborative haptic interaction by multiple users. In Virtual Dollhouse, users can observe physics law while constructing a dollhouse using existing building blocks, under gravity effects. In Virtual Stretcher, multiple users can collaborate on moving a stretcher together while feeling each other's haptic motions.

  14. Nonequilibrium steady states and resonant tunneling in time-periodically driven systems with interactions

    Science.gov (United States)

    Qin, Tao; Hofstetter, Walter

    2018-03-01

    Time-periodically driven systems are a versatile toolbox for realizing interesting effective Hamiltonians. Heating, caused by excitations to high-energy states, is a challenge for experiments. While most setups so far address the relatively weakly interacting regime, it is of general interest to study heating in strongly correlated systems. Using Floquet dynamical mean-field theory, we study nonequilibrium steady states (NESS) in the Falicov-Kimball model, with time-periodically driven kinetic energy or interaction. We systematically investigate the nonequilibrium properties of the NESS. For a driven kinetic energy, we show that resonant tunneling, where the interaction is an integer multiple of the driving frequency, plays an important role in the heating. In the strongly correlated regime, we show that this can be well understood using Fermi's golden rule and the Schrieffer-Wolff transformation for a time-periodically driven system. We furthermore demonstrate that resonant tunneling can be used to control the population of Floquet states to achieve "photodoping." For driven interactions introduced by an oscillating magnetic field near a widely adopted Feshbach resonance, we find that the double occupancy is strongly modulated. Our calculations apply to shaken ultracold-atom systems and to solid-state systems in a spatially uniform but time-dependent electric field. They are also closely related to lattice modulation spectroscopy. Our calculations are helpful to understand the latest experiments on strongly correlated Floquet systems.

  15. Non-unitarity, sterile neutrinos, and non-standard neutrino interactions

    Energy Technology Data Exchange (ETDEWEB)

    Blennow, Mattias [Department of Theoretical Physics, School of Engineering Sciences, KTH Royal Institute of Technology, Albanova University Center, 106 91 Stockholm (Sweden); Coloma, Pilar [Theoretical Physics Department, Fermi National Accelerator Laboratory, P.O. Box 500, Batavia, IL 60510 (United States); Fernandez-Martinez, Enrique; Hernandez-Garcia, Josu [Departamento de Física Teórica, Universidad Autónoma de Madrid, Cantoblanco E-28049 Madrid (Spain); Instituto de Física Teórica UAM/CSIC, Calle Nicolás Cabrera 13-15, Cantoblanco E-28049 Madrid (Spain); Lopez-Pavon, Jacobo [INFN, Sezione di Genova, via Dodecaneso 33, 16146 Genova (Italy); CERN, Theoretical Physics Department, Geneva (Switzerland)

    2017-04-27

    The simplest Standard Model extension to explain neutrino masses involves the addition of right-handed neutrinos. At some level, this extension will impact neutrino oscillation searches. In this work we explore the differences and similarities between the case in which these neutrinos are kinematically accessible (sterile neutrinos) or not (mixing matrix non-unitarity). We clarify apparent inconsistencies in the present literature when using different parametrizations to describe these effects and recast both limits in the popular neutrino non-standard interaction (NSI) formalism. We find that, in the limit in which sterile oscillations are averaged out at the near detector, their effects at the far detector coincide with non-unitarity at leading order, even in presence of a matter potential. We also summarize the present bounds existing in both limits and compare them with the expected sensitivities of near-future facilities taking the DUNE proposal as a benchmark. We conclude that non-unitarity effects are too constrained to impact present or near future neutrino oscillation facilities but that sterile neutrinos can play an important role at long baseline experiments. The role of the near detector is also discussed in detail.

  16. The tomography of human mobility - what do shortest-path trees reveal?

    Energy Technology Data Exchange (ETDEWEB)

    Thiemann, Christian [Eng. Sci. and Appl. Math, Northwestern University, Evanston, IL (United States); Max-Planck-Institute for Dynamics and Self-Organization, Goettingen (Germany); Grady, Daniel; Brockmann, Dirk [Eng. Sci. and Appl. Math, Northwestern University, Evanston, IL (United States)

    2010-07-01

    Similar to illustrating the anatomy of organs using pictures of tissue slices taken at various depths, we construct shortest-path trees of different nodes to create tomograms of large-scale human mobility networks. This tomography allows us to measure global properties of the system conditioned on a reference location in the network to gain a fuller characterization of a node. It also suggests a canonical coordinate system for representing complex networks and dynamical processes thereon in a simplified way, revealing a new symmetry in the human mobility networks we investigated. Furthermore, introducing the notion of tree similarity, we devised a new technique for clustering nodes with similar topological footprint, yielding a unique and efficient method for community identification and topological backbone extraction. We applied these methods to a multi-scale human mobility network obtained from the dollar-bill-tracking site wheresgoerge.com and to the U.S. and world-wide air transportation network.

  17. Measure solutions for non-local interaction PDEs with two species

    Energy Technology Data Exchange (ETDEWEB)

    Francesco, Marco Di [Department of Mathematical and Statistical Sciences, University of Bath, Claverton Down, Bath, BA2 7AY (United Kingdom); Fagioli, Simone [DISIM—Department of Information Engineering, Computer Science and Mathematics, University of L' Aquila, Via Vetoio 1 (Coppito) 67100 L' Aquila (AQ) (Italy)

    2013-10-01

    This paper presents a systematic existence and uniqueness theory of weak measure solutions for systems of non-local interaction PDEs with two species, which are the PDE counterpart of systems of deterministic interacting particles with two species. The main motivations behind those models arise in cell biology, pedestrian movements, and opinion formation. In case of symmetrizable systems (i.e. with cross-interaction potentials one multiple of the other), we provide a complete existence and uniqueness theory within (a suitable generalization of) the Wasserstein gradient flow theory in Ambrosio et al (2008 Gradient Flows in Metric Spaces and in the Space of Probability Measures (Lectures in Mathematics ETH Zürich) 2nd edn (Basel: Birkhäuser)) and Carrillo et al (2011 Duke Math. J. 156 229–71), which allows the consideration of interaction potentials with a discontinuous gradient at the origin. In the general case of non-symmetrizable systems, we provide an existence result for measure solutions which uses a semi-implicit version of the Jordan–Kinderlehrer–Otto (JKO) scheme (Jordan et al 1998 SIAM J. Math. Anal. 29 1–17), which holds in a reasonable non-smooth setting for the interaction potentials. Uniqueness in the non-symmetrizable case is proven for C{sup 2} potentials using a variant of the method of characteristics. (paper)

  18. Measure solutions for non-local interaction PDEs with two species

    International Nuclear Information System (INIS)

    Francesco, Marco Di; Fagioli, Simone

    2013-01-01

    This paper presents a systematic existence and uniqueness theory of weak measure solutions for systems of non-local interaction PDEs with two species, which are the PDE counterpart of systems of deterministic interacting particles with two species. The main motivations behind those models arise in cell biology, pedestrian movements, and opinion formation. In case of symmetrizable systems (i.e. with cross-interaction potentials one multiple of the other), we provide a complete existence and uniqueness theory within (a suitable generalization of) the Wasserstein gradient flow theory in Ambrosio et al (2008 Gradient Flows in Metric Spaces and in the Space of Probability Measures (Lectures in Mathematics ETH Zürich) 2nd edn (Basel: Birkhäuser)) and Carrillo et al (2011 Duke Math. J. 156 229–71), which allows the consideration of interaction potentials with a discontinuous gradient at the origin. In the general case of non-symmetrizable systems, we provide an existence result for measure solutions which uses a semi-implicit version of the Jordan–Kinderlehrer–Otto (JKO) scheme (Jordan et al 1998 SIAM J. Math. Anal. 29 1–17), which holds in a reasonable non-smooth setting for the interaction potentials. Uniqueness in the non-symmetrizable case is proven for C 2 potentials using a variant of the method of characteristics. (paper)

  19. Stability of periodic steady-state solutions to a non-isentropic Euler-Poisson system

    Science.gov (United States)

    Liu, Cunming; Peng, Yue-Jun

    2017-06-01

    We study the stability of periodic smooth solutions near non-constant steady-states for a non-isentropic Euler-Poisson system without temperature damping term. The system arises in the theory of semiconductors for which the doping profile is a given smooth function. In this stability problem, there are no special restrictions on the size of the doping profile, but only on the size of the perturbation. We prove that small perturbations of periodic steady-states are exponentially stable for large time. For this purpose, we introduce new variables and choose a non-diagonal symmetrizer of the full Euler equations to recover dissipation estimates. This also allows to make the proof of the stability result very simple and concise.

  20. NPR Lenses : Interactive Tools for Non-photorealistic Line Drawings

    NARCIS (Netherlands)

    Neumann, Petra; Isenberg, Tobias; Carpendale, Sheelagh

    2007-01-01

    NPR Lenses is an interactive technique for producing expressive non-photorealistic renderings. It provides an intuitive visual interaction tool for illustrators, allowing them to seamlessly apply a large variety of emphasis techniques. Advantages of 3D scene manipulation are combined with the

  1. ARTICLES: Thermohydrodynamic models of the interaction of pulse-periodic radiation with matter

    Science.gov (United States)

    Arutyunyan, R. V.; Baranov, V. Yu; Bol'shov, Leonid A.; Malyuta, D. D.; Mezhevov, V. S.; Pis'mennyĭ, V. D.

    1987-02-01

    Experimental and theoretical investigations were made of the processes of drilling and deep melting of metals by pulsed and pulse-periodic laser radiation. Direct photography of the surface revealed molten metal splashing due to interaction with single CO2 laser pulses. A proposed thermohydrodynamic model was used to account for the experimental results and to calculate the optimal parameters of pulse-periodic radiation needed for deep melting. The melt splashing processes were simulated numerically.

  2. Sino-Japanese Interaction via Chinese Junks in the Edo Period

    OpenAIRE

    MATSUURA, Akira

    2010-01-01

    To maintain its policy of national isolation during the Edo period, Japan restricted contact with the outside world to Dutch merchant ships and Chinese junks at the Japanese port of Nagasaki. Sino-Japanese interaction consisted not only of trade in goods, but also of cultural and scholarly exchanges. This paper will examine how this unofficial trade affected both Japan and China from a cultural perspective.

  3. Non-equilibrium magnetic interactions in strongly correlated systems

    Energy Technology Data Exchange (ETDEWEB)

    Secchi, A., E-mail: a.secchi@science.ru.nl [Institute for Molecules and Materials, Radboud University Nijmegen, 6525 AJ Nijmegen (Netherlands); Brener, S.; Lichtenstein, A.I. [Institut für Theoretische Physik, Universitat Hamburg, Jungiusstraße 9, D-20355 Hamburg (Germany); Katsnelson, M.I. [Institute for Molecules and Materials, Radboud University Nijmegen, 6525 AJ Nijmegen (Netherlands)

    2013-06-15

    We formulate a low-energy theory for the magnetic interactions between electrons in the multi-band Hubbard model under non-equilibrium conditions determined by an external time-dependent electric field which simulates laser-induced spin dynamics. We derive expressions for dynamical exchange parameters in terms of non-equilibrium electronic Green functions and self-energies, which can be computed, e.g., with the methods of time-dependent dynamical mean-field theory. Moreover, we find that a correct description of the system requires, in addition to exchange, a new kind of magnetic interaction, that we name twist exchange, which formally resembles Dzyaloshinskii–Moriya coupling, but is not due to spin–orbit, and is actually due to an effective three-spin interaction. Our theory allows the evaluation of the related time-dependent parameters as well. -- Highlights: •We develop a theory for magnetism of strongly correlated systems out of equilibrium. •Our theory is suitable for laser-induced ultrafast magnetization dynamics. •We write time-dependent exchange parameters in terms of electronic Green functions. •We find a new magnetic interaction, a “twist exchange”. •We give general expressions for magnetic noise in itinerant-electron systems.

  4. The period-age relation for cepheids

    International Nuclear Information System (INIS)

    Efremov, Yu.N.

    1978-01-01

    The list of 119 cepheid-members of 55 clusters and associations of the Magellanic Clouds, the Galaxy, and M31 is given. The period-age relation is found from the data on 64 cepheids in 29 clusters for which the age determinations are available, the ages of extragalactic clusters were determined mainly from their integral colours. The U-B colours are found to be of much better age parameters than the B-V ones. The composite period-age relation agrees well with the theoretical one. The observed dispersion of the period-age relation leads to an estimate of the age dispersion about 1x10 7 years in the associations. Some peculiarities of the cepheids with the shortest periods amongst others in the same clusters are probably explained if they are overtone pulsators. The period-age relation may be used for an investigation of the recent history of star formation in the galaxies. This relation allows to determine the age gradient across the spiral arm in M31 which is in agreement with the density wave theory predictions. The distribution of cepheids in our Galaxy and neighbouring galaxies is consistent with the conception of star formation lasting for some dozen million years in cells with a dimension of some hundreds of parsecs

  5. Non-linear electromagnetic interactions in thermal QED

    International Nuclear Information System (INIS)

    Brandt, F.T.; Frenkel, J.

    1994-08-01

    The behavior of the non-linear interactions between electromagnetic fields at high temperature is examined. It is shown that, in general, the log(T) dependence on the temperature of the Green functions is simply related to their UV behavior at zero-temperature. It is argued that the effective action describing the nonlinear thermal electromagnetic interactions has a finite limit as T -> ∞. This thermal action approaches, in the long wavelength limit, the negative of the corresponding zero-temperature action. (author). 12 refs, 1 fig

  6. NON-LINEAR MODELING OF THE RHIC INTERACTION REGIONS

    International Nuclear Information System (INIS)

    TOMAS, R.; FISCHER, W.; JAIN, A.; LUO, Y.; PILAT, F.

    2004-01-01

    For RHIC's collision lattices the dominant sources of transverse non-linearities are located in the interaction regions. The field quality is available for most of the magnets in the interaction regions from the magnetic measurements, or from extrapolations of these measurements. We discuss the implementation of these measurements in the MADX models of the Blue and the Yellow rings and their impact on beam stability

  7. Inferring anatomical therapeutic chemical (ATC) class of drugs using shortest path and random walk with restart algorithms.

    Science.gov (United States)

    Chen, Lei; Liu, Tao; Zhao, Xian

    2018-06-01

    The anatomical therapeutic chemical (ATC) classification system is a widely accepted drug classification scheme. This system comprises five levels and includes several classes in each level. Drugs are classified into classes according to their therapeutic effects and characteristics. The first level includes 14 main classes. In this study, we proposed two network-based models to infer novel potential chemicals deemed to belong in the first level of ATC classification. To build these models, two large chemical networks were constructed using the chemical-chemical interaction information retrieved from the Search Tool for Interactions of Chemicals (STITCH). Two classic network algorithms, shortest path (SP) and random walk with restart (RWR) algorithms, were executed on the corresponding network to mine novel chemicals for each ATC class using the validated drugs in a class as seed nodes. Then, the obtained chemicals yielded by these two algorithms were further evaluated by a permutation test and an association test. The former can exclude chemicals produced by the structure of the network, i.e., false positive discoveries. By contrast, the latter identifies the most important chemicals that have strong associations with the ATC class. Comparisons indicated that the two models can provide quite dissimilar results, suggesting that the results yielded by one model can be essential supplements for those obtained by the other model. In addition, several representative inferred chemicals were analyzed to confirm the reliability of the results generated by the two models. This article is part of a Special Issue entitled: Accelerating Precision Medicine through Genetic and Genomic Big Data Analysis edited by Yudong Cai & Tao Huang. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Extended shortest path selection for package routing of complex networks

    Science.gov (United States)

    Ye, Fan; Zhang, Lei; Wang, Bing-Hong; Liu, Lu; Zhang, Xing-Yi

    The routing strategy plays a very important role in complex networks such as Internet system and Peer-to-Peer networks. However, most of the previous work concentrates only on the path selection, e.g. Flooding and Random Walk, or finding the shortest path (SP) and rarely considering the local load information such as SP and Distance Vector Routing. Flow-based Routing mainly considers load balance and still cannot achieve best optimization. Thus, in this paper, we propose a novel dynamic routing strategy on complex network by incorporating the local load information into SP algorithm to enhance the traffic flow routing optimization. It was found that the flow in a network is greatly affected by the waiting time of the network, so we should not consider only choosing optimized path for package transformation but also consider node congestion. As a result, the packages should be transmitted with a global optimized path with smaller congestion and relatively short distance. Analysis work and simulation experiments show that the proposed algorithm can largely enhance the network flow with the maximum throughput within an acceptable calculating time. The detailed analysis of the algorithm will also be provided for explaining the efficiency.

  9. Unraveling spurious properties of interaction networks with tailored random networks.

    Directory of Open Access Journals (Sweden)

    Stephan Bialonski

    Full Text Available We investigate interaction networks that we derive from multivariate time series with methods frequently employed in diverse scientific fields such as biology, quantitative finance, physics, earth and climate sciences, and the neurosciences. Mimicking experimental situations, we generate time series with finite length and varying frequency content but from independent stochastic processes. Using the correlation coefficient and the maximum cross-correlation, we estimate interdependencies between these time series. With clustering coefficient and average shortest path length, we observe unweighted interaction networks, derived via thresholding the values of interdependence, to possess non-trivial topologies as compared to Erdös-Rényi networks, which would indicate small-world characteristics. These topologies reflect the mostly unavoidable finiteness of the data, which limits the reliability of typically used estimators of signal interdependence. We propose random networks that are tailored to the way interaction networks are derived from empirical data. Through an exemplary investigation of multichannel electroencephalographic recordings of epileptic seizures--known for their complex spatial and temporal dynamics--we show that such random networks help to distinguish network properties of interdependence structures related to seizure dynamics from those spuriously induced by the applied methods of analysis.

  10. Denjoy minimal sets and Birkhoff periodic orbits for non-exact monotone twist maps

    Science.gov (United States)

    Qin, Wen-Xin; Wang, Ya-Nan

    2018-06-01

    A non-exact monotone twist map φbarF is a composition of an exact monotone twist map φ bar with a generating function H and a vertical translation VF with VF ((x , y)) = (x , y - F). We show in this paper that for each ω ∈ R, there exists a critical value Fd (ω) ≥ 0 depending on H and ω such that for 0 ≤ F ≤Fd (ω), the non-exact twist map φbarF has an invariant Denjoy minimal set with irrational rotation number ω lying on a Lipschitz graph, or Birkhoff (p , q)-periodic orbits for rational ω = p / q. Like the Aubry-Mather theory, we also construct heteroclinic orbits connecting Birkhoff periodic orbits, and show that quasi-periodic orbits in these Denjoy minimal sets can be approximated by periodic orbits. In particular, we demonstrate that at the critical value F =Fd (ω), the Denjoy minimal set is not uniformly hyperbolic and can be approximated by smooth curves.

  11. Periodic travelling and non-travelling wave solutions of the nonlinear Klein-Gordon equation with imaginary mass

    International Nuclear Information System (INIS)

    Tang Xiaoyan; Shukla, Padma Kant

    2008-01-01

    Exact solutions, including the periodic travelling and non-travelling wave solutions, are presented for the nonlinear Klein-Gordon equation with imaginary mass. Some arbitrary functions are permitted in the periodic non-travelling wave solutions, which contribute to various high dimensional nonlinear structures

  12. The effects of Dresselhaus and Rashba spin-orbit interactions on the electron tunneling in a non-magnetic heterostructure

    International Nuclear Information System (INIS)

    Lu Jianduo; Li Jianwen

    2010-01-01

    We theoretically investigate the electron transport properties in a non-magnetic heterostructure with both Dresselhaus and Rashba spin-orbit interactions. The detailed-numerical results show that (1) the large spin polarization can be achieved due to Dresselhaus and Rashba spin-orbit couplings induced splitting of the resonant level, although the magnetic field is zero in such a structure, (2) the Rashba spin-orbit coupling plays a greater role on the spin polarization than the Dresselhaus spin-orbit interaction does, and (3) the transmission probability and the spin polarization both periodically change with the increase of the well width.

  13. Non-Linear Interactive Stories in Computer Games

    DEFF Research Database (Denmark)

    Bangsø, Olav; Jensen, Ole Guttorm; Kocka, Tomas

    2003-01-01

    The paper introduces non-linear interactive stories (NOLIST) as a means to generate varied and interesting stories for computer games automatically. We give a compact representation of a NOLIST based on the specification of atomic stories, and show how to build an object-oriented Bayesian network...

  14. Fast and accurate global multiphase arrival tracking: the irregular shortest-path method in a 3-D spherical earth model

    Science.gov (United States)

    Huang, Guo-Jiao; Bai, Chao-Ying; Greenhalgh, Stewart

    2013-09-01

    The traditional grid/cell-based wavefront expansion algorithms, such as the shortest path algorithm, can only find the first arrivals or multiply reflected (or mode converted) waves transmitted from subsurface interfaces, but cannot calculate the other later reflections/conversions having a minimax time path. In order to overcome the above limitations, we introduce the concept of a stationary minimax time path of Fermat's Principle into the multistage irregular shortest path method. Here we extend it from Cartesian coordinates for a flat earth model to global ray tracing of multiple phases in a 3-D complex spherical earth model. The ray tracing results for 49 different kinds of crustal, mantle and core phases show that the maximum absolute traveltime error is less than 0.12 s and the average absolute traveltime error is within 0.09 s when compared with the AK135 theoretical traveltime tables for a 1-D reference model. Numerical tests in terms of computational accuracy and CPU time consumption indicate that the new scheme is an accurate, efficient and a practical way to perform 3-D multiphase arrival tracking in regional or global traveltime tomography.

  15. Stochastic sensitivity analysis of periodic attractors in non-autonomous nonlinear dynamical systems based on stroboscopic map

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Kong-Ming, E-mail: kmguo@xidian.edu.cn [School of Electromechanical Engineering, Xidian University, P.O. Box 187, Xi' an 710071 (China); Jiang, Jun, E-mail: jun.jiang@mail.xjtu.edu.cn [State Key Laboratory for Strength and Vibration, Xi' an Jiaotong University, Xi' an 710049 (China)

    2014-07-04

    To apply stochastic sensitivity function method, which can estimate the probabilistic distribution of stochastic attractors, to non-autonomous dynamical systems, a 1/N-period stroboscopic map for a periodic motion is constructed in order to discretize the continuous cycle into a discrete one. In this way, the sensitivity analysis of a cycle for discrete map can be utilized and a numerical algorithm for the stochastic sensitivity analysis of periodic solutions of non-autonomous nonlinear dynamical systems under stochastic disturbances is devised. An external excited Duffing oscillator and a parametric excited laser system are studied as examples to show the validity of the proposed method. - Highlights: • A method to analyze sensitivity of stochastic periodic attractors in non-autonomous dynamical systems is proposed. • Probabilistic distribution around periodic attractors in an external excited Φ{sup 6} Duffing system is obtained. • Probabilistic distribution around a periodic attractor in a parametric excited laser system is determined.

  16. Non-periodic homogenization of 3-D elastic media for the seismic wave equation

    Science.gov (United States)

    Cupillard, Paul; Capdeville, Yann

    2018-05-01

    Because seismic waves have a limited frequency spectrum, the velocity structure of the Earth that can be extracted from seismic records has a limited resolution. As a consequence, one obtains smooth images from waveform inversion, although the Earth holds discontinuities and small scales of various natures. Within the last decade, the non-periodic homogenization method shed light on how seismic waves interact with small geological heterogeneities and `see' upscaled properties. This theory enables us to compute long-wave equivalent density and elastic coefficients of any media, with no constraint on the size, the shape and the contrast of the heterogeneities. In particular, the homogenization leads to the apparent, structure-induced anisotropy. In this paper, we implement this method in 3-D and show 3-D tests for the very first time. The non-periodic homogenization relies on an asymptotic expansion of the displacement and the stress involved in the elastic wave equation. Limiting ourselves to the order 0, we show that the practical computation of an upscaled elastic tensor basically requires (i) to solve an elastostatic problem and (ii) to low-pass filter the strain and the stress associated with the obtained solution. The elastostatic problem consists in finding the displacements due to local unit strains acting in all directions within the medium to upscale. This is solved using a parallel, highly optimized finite-element code. As for the filtering, we rely on the finite-element quadrature to perform the convolution in the space domain. We end up with an efficient numerical tool that we apply on various 3-D models to test the accuracy and the benefit of the homogenization. In the case of a finely layered model, our method agrees with results derived from Backus. In a more challenging model composed by a million of small cubes, waveforms computed in the homogenized medium fit reference waveforms very well. Both direct phases and complex diffracted waves are

  17. Long-Period Tidal Variations in the Length of Day

    Science.gov (United States)

    Ray, Richard D.; Erofeeva, Svetlana Y.

    2014-01-01

    A new model of long-period tidal variations in length of day is developed. The model comprises 80 spectral lines with periods between 18.6 years and 4.7 days, and it consistently includes effects of mantle anelasticity and dynamic ocean tides for all lines. The anelastic properties followWahr and Bergen; experimental confirmation for their results now exists at the fortnightly period, but there remains uncertainty when extrapolating to the longest periods. The ocean modeling builds on recent work with the fortnightly constituent, which suggests that oceanic tidal angular momentum can be reliably predicted at these periods without data assimilation. This is a critical property when modeling most long-period tides, for which little observational data exist. Dynamic ocean effects are quite pronounced at shortest periods as out-of-phase rotation components become nearly as large as in-phase components. The model is tested against a 20 year time series of space geodetic measurements of length of day. The current international standard model is shown to leave significant residual tidal energy, and the new model is found to mostly eliminate that energy, with especially large variance reduction for constituents Sa, Ssa, Mf, and Mt.

  18. IUE observations of long period eclipsing binaries: a study of accretion onto non-degenerate stars

    International Nuclear Information System (INIS)

    Plavec, M.J.

    1980-01-01

    It has long been thought that β Lyrae is a unique system, by virtue of its UV spectrum and its nature. The author argues that a whole class of interacting long-period binaries exists, similar to β Lyrae. According to IUE observations made in 1978-79 this group comprises: RX Cas, SX Cas, V 367 Cyg, W Cru, β Lyr, and W Ser. AR Pav is a transition case linking them with the symbiotics. The author also suggests that HD 218393 (KX And), HD 72754, and HD 51480 are their non-eclipsing counterparts. The whole group is called the W Serpentis stars. These systems are mass-transfering binaries (case B) in which the mass transfer rate is relatively high, probably on the order 10 -6 to 10 -4 solar masses/year. They display an ultraviolet continuum with a color temperature definitely higher than the one observed in the optical region. Even more characteristical is the presence of strong emission lines of N V, C IV, Si IV, Fe III, Al III, and lower ions of C and Si. The author discusses these phenomena on the assumption that they are due to accretion onto non-degenerate stars. (Auth.)

  19. Nature and consequences of non-covalent interactions between flavonoids and macronutrients in foods.

    Science.gov (United States)

    Bordenave, Nicolas; Hamaker, Bruce R; Ferruzzi, Mario G

    2014-01-01

    Many of the potential health benefits of flavonoids have been associated with their specific chemical and biological properties including their ability to interact and bind non-covalently to macronutrients in foods. While flavonoid-protein interactions and binding have been the subject of intensive study, significantly less is understood about non-covalent interactions with carbohydrates and lipids. These interactions with macronutrients are likely to impact both the flavonoid properties in foods, such as their radical scavenging activity, and the food or beverage matrix itself, including their taste, texture and other sensorial properties. Overall, non-covalent binding of flavonoids with macronutrients is primarily driven by van der Waals interactions. From the flavonoid perspective, these interactions are modulated by characteristics such as degree of polymerization, molecular flexibility, number of external hydroxyl groups, or number of terminal galloyl groups. From the macronutrient standpoint, electrostatic and ionic interactions are generally predominant with carbohydrates, while hydrophobic interactions are generally predominant with lipids and mainly limited to interactions with flavonols. All of these interactions are involved in flavonoid-protein interactions. While primarily associated with undesirable characteristics in foods and beverages, such as astringency, negative impact on macronutrient digestibility and hazing, more recent efforts have attempted to leverage these interactions to develop controlled delivery systems or strategies to enhance flavonoids bioavailability. This paper aims at reviewing the fundamental bases for non-covalent interactions, their occurrence in food and beverage systems and their impact on the physico-chemical, organoleptic and some nutritional properties of food.

  20. Non-periodic pseudo-random numbers used in Monte Carlo calculations

    Science.gov (United States)

    Barberis, Gaston E.

    2007-09-01

    The generation of pseudo-random numbers is one of the interesting problems in Monte Carlo simulations, mostly because the common computer generators produce periodic numbers. We used simple pseudo-random numbers generated with the simplest chaotic system, the logistic map, with excellent results. The numbers generated in this way are non-periodic, which we demonstrated for 1013 numbers, and they are obtained in a deterministic way, which allows to repeat systematically any calculation. The Monte Carlo calculations are the ideal field to apply these numbers, and we did it for simple and more elaborated cases. Chemistry and Information Technology use this kind of simulations, and the application of this numbers to quantum Monte Carlo and cryptography is immediate. I present here the techniques to calculate, analyze and use these pseudo-random numbers, show that they lack periodicity up to 1013 numbers and that they are not correlated.

  1. Non-periodic pseudo-random numbers used in Monte Carlo calculations

    International Nuclear Information System (INIS)

    Barberis, Gaston E.

    2007-01-01

    The generation of pseudo-random numbers is one of the interesting problems in Monte Carlo simulations, mostly because the common computer generators produce periodic numbers. We used simple pseudo-random numbers generated with the simplest chaotic system, the logistic map, with excellent results. The numbers generated in this way are non-periodic, which we demonstrated for 10 13 numbers, and they are obtained in a deterministic way, which allows to repeat systematically any calculation. The Monte Carlo calculations are the ideal field to apply these numbers, and we did it for simple and more elaborated cases. Chemistry and Information Technology use this kind of simulations, and the application of this numbers to quantum Monte Carlo and cryptography is immediate. I present here the techniques to calculate, analyze and use these pseudo-random numbers, show that they lack periodicity up to 10 13 numbers and that they are not correlated

  2. An explicit method in non-linear soil-structure interaction

    International Nuclear Information System (INIS)

    Kunar, R.R.

    1981-01-01

    The explicit method of analysis in the time domain is ideally suited for the solution of transient dynamic non-linear problems. Though the method is not new, its application to seismic soil-structure interaction is relatively new and deserving of public discussion. This paper describes the principles of the explicit approach in soil-structure interaction and it presents a simple algorithm that can be used in the development of explicit computer codes. The paper also discusses some of the practical considerations like non-reflecting boundaries and time steps. The practicality of the method is demonstrated using a computer code, PRESS, which is used to compare the treatment of strain-dependent properties using average strain levels over the whole time history (the equivalent linear method) and using the actual strain levels at every time step to modify the soil properties (non-linear method). (orig.)

  3. A survey for very short-period planets in the Kepler data

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, Brian; Stark, Christopher C.; Chambers, John [Carnegie Institution for Science, 5241 Broad Branch Road NW, Washington, DC 20015 (United States); Adams, Elisabeth R. [Planetary Science Institute, 1700 East Fort Lowell, Suite 106, Tucson, AZ 85719 (United States); Deming, Drake, E-mail: bjackson@dtm.ciw.edu [Department of Astronomy, University of Maryland at College Park, College Park, MD 20742 (United States)

    2013-12-20

    We conducted a search for very short-period transiting objects in the publicly available Kepler data set. Our preliminary survey has revealed four planetary candidates, all with orbital periods less than 12 hr. We have analyzed the data for these candidates using photometric models that include transit light curves, ellipsoidal variations, and secondary eclipses to constrain the candidates' radii, masses, and effective temperatures. Even with masses of only a few Earth masses, the candidates' short periods mean that they may induce stellar radial velocity signals (a few m s{sup –1}) detectable by currently operating facilities. The origins of such short-period planets are unclear, but we discuss the possibility that they may be the remnants of disrupted hot Jupiters. Whatever their origins, if confirmed as planets, these candidates would be among the shortest-period planets ever discovered. Such planets would be particularly amenable to discovery by the planned TESS mission.

  4. A survey for very short-period planets in the Kepler data

    International Nuclear Information System (INIS)

    Jackson, Brian; Stark, Christopher C.; Chambers, John; Adams, Elisabeth R.; Deming, Drake

    2013-01-01

    We conducted a search for very short-period transiting objects in the publicly available Kepler data set. Our preliminary survey has revealed four planetary candidates, all with orbital periods less than 12 hr. We have analyzed the data for these candidates using photometric models that include transit light curves, ellipsoidal variations, and secondary eclipses to constrain the candidates' radii, masses, and effective temperatures. Even with masses of only a few Earth masses, the candidates' short periods mean that they may induce stellar radial velocity signals (a few m s –1 ) detectable by currently operating facilities. The origins of such short-period planets are unclear, but we discuss the possibility that they may be the remnants of disrupted hot Jupiters. Whatever their origins, if confirmed as planets, these candidates would be among the shortest-period planets ever discovered. Such planets would be particularly amenable to discovery by the planned TESS mission.

  5. STABLE STATIONARY STATES OF NON-LOCAL INTERACTION EQUATIONS

    KAUST Repository

    FELLNER, KLEMENS; RAOUL, GAË L

    2010-01-01

    .r.t. shifts and reallocations of individual Dirac masses, and (iii) show that these linear stability conditions imply local non-linear stability. Finally, we show that for regular repulsive interaction potential Wε converging to a singular repulsive

  6. Constraints of a parity-conserving/time-reversal-non-conserving interaction

    International Nuclear Information System (INIS)

    Oers, Willem T.H. van

    2002-01-01

    Time-Reversal-Invariance non-conservation has for the first time been unequivocally demonstrated in a direct measurement at CPLEAR. One then can ask the question: What about tests of time-reversal-invariance in systems other than the kaon system? Tests of time-reversal-invariance can be distinguished as belonging to two classes: the first one deals with time-reversal-invariance-non-conserving (T-odd)/parity violating (P-odd) interactions, while the second one deals with T-odd/P-even interactions (assuming CPT conservation this implies C-conjugation non-conservation). Limits on a T-odd/P-odd interaction follow from measurements of the electric dipole moment of the neutron ( -26 e.cm [95% C.L.]). It provides a limit on a T-odd/P-odd pion-nucleon coupling constant which is less than 10 -4 times the weak interaction strength. Experimental limits on a T-odd/P-even interaction are much less stringent. Following the standard approach of describing the nucleon-nucleon interaction in terms of meson exchanges, it can be shown that only charged ρ-meson exchange and A 1 -meson exchange can lead to a T-odd/P-even interaction. The better constraints stem from measurements of the electric dipole moment of the neutron and from measurements of charge-symmetry breaking in neutron-proton elastic scattering. The latter experiments were executed at TRIUMF (497 and 347 MeV) and at IUCF (183 MeV). All other experiments, like detailed balance experiments, polarization - analyzing power difference determinations, and five-fold correlation experiments with polarized incident nucleons and aligned nuclear targets, have been shown to be at least an order to magnitude less sensitive. Is there room for further experimentation?

  7. Principles of interactions in non-aqueous electrolyte solutions

    NARCIS (Netherlands)

    Lyklema, J.

    2013-01-01

    In this paper a review is presented on the molecular interactions in non-aqueous media of low dielectric permittivity. Qualitative and quantitative distinctions with aqueous solutions are emphasized. The reviewed themes include dispersion forces, dissociation and association equilibria,

  8. Study of horizontal-vertical interactive Sway Rocking (SR) model for basemat uplift. Part 2: non-linear response analysis and validation

    International Nuclear Information System (INIS)

    Momma, T.; Shirahama, K.; Suzuki, K.; Ogihara, M.

    1995-01-01

    Non-linear earthquake response analyses of a BWR MARK-II type nuclear reactor building are conducted by using a Sway Rocking model (SR model) proposed in Part 1 considering the interaction between horizontal and vertical motion. The results are compared with those of accurate mathematical model using the Green Function method. Horizontal response of the SR model agrees very well with that of the Green Function model. The floor response spectra of induced vertical motions by both methods are also corresponding well in periodic characteristics as well as peak-levels. From these results, it is confirmed that the horizontal-vertical interactive SR model is applicable to non-linear response analyses considering basemat uplift. Based on the comparison of the induced vertical motions due to basemat uplift by both methods, an application limit of the horizontal-vertical interactive SR model is set up at the ground contact ratio of about 50%. (author). 4 refs., 8 figs., 1 tab

  9. Period concatenation underlies interactions between gamma and beta rhythms in neocortex

    Directory of Open Access Journals (Sweden)

    Anita K Roopun

    2008-04-01

    Full Text Available The neocortex generates rhythmic electrical activity over a frequency range covering many decades. Specific cognitive and motor states are associated with oscillations in discrete frequency bands within this range, but it is not known whether interactions and transitions between distinct frequencies are of functional importance. When coexpressed rhythms have frequencies that differ by a factor of two or more interactions can be seen in terms of phase synchronization. Larger frequency differences can result in interactions in the form of nesting of faster frequencies within slower ones by a process of amplitude modulation. It is not known how coexpressed rhythms, whose frequencies differ by less than a factor of two may interact. Here we show that two frequencies (gamma – 40 Hz and beta2 – 25 Hz, coexpressed in superficial and deep cortical laminae with low temporal interaction, can combine to generate a third frequency (beta1 – 15 Hz showing strong temporal interaction. The process occurs via period concatenation, with basic rhythm-generating microcircuits underlying gamma and beta2 rhythms forming the building blocks of the beta1 rhythm by a process of addition. The mean ratio of adjacent frequency components was a constant – approximately the golden mean – which served to both minimize temporal interactions, and permit multiple transitions, between frequencies. The resulting temporal landscape may provide a framework for multiplexing – parallel information processing on multiple temporal scales.

  10. The circumnuclear environment of nearby non-interacting Seyfert galaxies

    International Nuclear Information System (INIS)

    Pogge, R.W.

    1988-01-01

    An investigation into the physical conditions prevailing in the regions immediately surrounding the active nuclei in 20 nearby, non-interacting Seyfert galaxies is reported. CCD interference-band images isolating the bright emission lines of Hα + [N II] λλ6548, 6583 and [O III] λ5007 have been obtained to search for spatially extended circumnuclear emission regions. Long-slit, low resolution spectrophotometry of interesting cases was used to probe the ionization state of the extended emission regions. For comparison, a CCD Hα + [N II] interference-band imaging survey of a statistically significant sample of 91 bright non-Seyfert spiral galaxies meeting the same non-interaction criteria has been carried out. Only three out of nine Seyfert 1s have spatially extended ionized gas regions compared with eight out of eleven Seyfert 2s. Enhanced circumnuclear star formation is uncommon to both Seyfert 1s and 2s. Extended emission in Seyfert 1s has essentially the same morphology in both Hα + [N II] and [O III] emission. In the Seyfert 2s, the Hα + [N II] and [O III] images show different extended emission morphologies. The [O III] emission regions appear as either one- or two-sided structures, four of which are resolved into two distinct cones of high-ionization gas emanating from the active nucleus. The morphology and ionization of these regions suggest collimation of the nuclear ionizing radiation field. The 91 non-interacting non-Seyfert spiral galaxies exhibit a rich variety of nuclear and circumnuclear emission-line structures ranging from no emission detected to bright stellar nuclei with complicated circumnuclear emission regions extending for many kiloparsecs

  11. Non-standard neutrino interactions in the mu–tau sector

    Directory of Open Access Journals (Sweden)

    Irina Mocioiu

    2015-04-01

    Full Text Available We discuss neutrino mass hierarchy implications arising from the effects of non-standard neutrino interactions on muon rates in high statistics atmospheric neutrino oscillation experiments like IceCube DeepCore. We concentrate on the mu–tau sector, which is presently the least constrained. It is shown that the magnitude of the effects depends strongly on the sign of the ϵμτ parameter describing this non-standard interaction. A simple analytic model is used to understand the parameter space where differences between the two signs are maximized. We discuss how this effect is partially degenerate with changing the neutrino mass hierarchy, as well as how this degeneracy could be lifted.

  12. Non-periodic inspection optimization of multi-component and k-out-of-m systems

    International Nuclear Information System (INIS)

    Hajipour, Yassin; Taghipour, Sharareh

    2016-01-01

    This paper proposes a model to find the optimal non-periodic inspection interval over a finite planning horizon for two types of multi-component repairable systems. The first system contains hard-type and soft-type components, and the second system is a k-out-of-m system with m identical components. The failures of components in both systems follow a non-homogeneous Poisson process. A component can be a single part such as battery or line cord, or a subsystem, such as circuit breaker or charger in an infusion pump, which depending on their failures could be either replaced or minimally repaired according to their ages at failure. The systems are inspected at scheduled inspections or when an event of opportunistic inspection or a system failure occur. We develop a model to find the optimal inspection scheme for each system, which results in the minimum total expected cost over the system's lifecycle. We first develop a simulation model to obtain the total expected cost for a given non-periodic inspection scheme, and then integrate the simulation model with a genetic algorithm to obtain the optimal scheme more efficiently. - Highlights: • Non-periodic inspection optimization of two complex systems. • One system consists of soft-type and hard-type components. • The second system is a k-out-of-m system. • Integration of a simulation model and the genetic algorithm. • The model can be used when inspection is challenging or costly.

  13. Mathematical Analysis for Non-reciprocal-interaction-based Model of Collective Behavior

    Science.gov (United States)

    Kano, Takeshi; Osuka, Koichi; Kawakatsu, Toshihiro; Ishiguro, Akio

    2017-12-01

    In many natural and social systems, collective behaviors emerge as a consequence of non-reciprocal interaction between their constituents. As a first step towards understanding the core principle that underlies these phenomena, we previously proposed a minimal model of collective behavior based on non-reciprocal interactions by drawing inspiration from friendship formation in human society, and demonstrated via simulations that various non-trivial patterns emerge by changing parameters. In this study, a mathematical analysis of the proposed model wherein the system size is small is performed. Through the analysis, the mechanism of the transition between several patterns is elucidated.

  14. Evidence for gene-environment interaction in a genome wide study of isolated, non-syndromic cleft palate

    Science.gov (United States)

    Beaty, Terri H.; Ruczinski, Ingo; Murray, Jeffrey C.; Marazita, Mary L.; Munger, Ronald G.; Hetmanski, Jacqueline B.; Murray, Tanda; Redett, Richard J.; Fallin, M. Daniele; Liang, Kung Yee; Wu, Tao; Patel, Poorav J.; Jin, Sheng C.; Zhang, Tian Xiao; Schwender, Holger; Wu-Chou, Yah Huei; Chen, Philip K; Chong, Samuel S; Cheah, Felicia; Yeow, Vincent; Ye, Xiaoqian; Wang, Hong; Huang, Shangzhi; Jabs, Ethylin W.; Shi, Bing; Wilcox, Allen J.; Lie, Rolv T.; Jee, Sun Ha; Christensen, Kaare; Doheny, Kimberley F.; Pugh, Elizabeth W.; Ling, Hua; Scott, Alan F.

    2011-01-01

    Non-syndromic cleft palate (CP) is a common birth defect with a complex and heterogeneous etiology involving both genetic and environmental risk factors. We conducted a genome wide association study (GWAS) using 550 case-parent trios, ascertained through a CP case collected in an international consortium. Family based association tests of single nucleotide polymorphisms (SNP) and three common maternal exposures (maternal smoking, alcohol consumption and multivitamin supplementation) were used in a combined 2 df test for gene (G) and gene-environment (G×E) interaction simultaneously, plus a separate 1 df test for G×E interaction alone. Conditional logistic regression models were used to estimate effects on risk to exposed and unexposed children. While no SNP achieved genome wide significance when considered alone, markers in several genes attained or approached genome wide significance when G×E interaction was included. Among these, MLLT3 and SMC2 on chromosome 9 showed multiple SNPs resulting in increased risk if the mother consumed alcohol during the peri-conceptual period (3 months prior to conception through the first trimester). TBK1 on chr. 12 and ZNF236 on chr. 18 showed multiple SNPs associated with higher risk of CP in the presence of maternal smoking. Additional evidence of reduced risk due to G×E interaction in the presence of multivitamin supplementation was observed for SNPs in BAALC on chr. 8. These results emphasize the need to consider G×E interaction when searching for genes influencing risk to complex and heterogeneous disorders, such as non-syndromic CP. PMID:21618603

  15. Internal crisis in a second-order non-linear non-autonomous electronic oscillator

    International Nuclear Information System (INIS)

    Stavrinides, S.G.; Deliolanis, N.C.; Miliou, A.N.; Laopoulos, Th.; Anagnostopoulos, A.N.

    2008-01-01

    The internal crisis of a second-order non-linear non-autonomous chaotic electronic circuit is studied. The phase portraits consist of two interacting sub-attractors, a chaotic and a periodic one. Maximal Lyapunov exponents were calculated, for both the periodic and the chaotic waveforms, in order to confirm their nature. Transitions between the chaotic and the periodic sub-attractors become more frequent by increasing the circuit driving frequency. The frequency distribution of the corresponding laminar lengths and their average values indicate that an internal crisis takes place in this circuit, manifested in the intermittent behaviour of the corresponding orbits

  16. Network structure beyond food webs: mapping non-trophic and trophic interactions on Chilean rocky shores.

    Science.gov (United States)

    Sonia Kéfi; Berlow, Eric L; Wieters, Evie A; Joppa, Lucas N; Wood, Spencer A; Brose, Ulrich; Navarrete, Sergio A

    2015-01-01

    How multiple types of non-trophic interactions map onto trophic networks in real communities remains largely unknown. We present the first effort, to our knowledge, describing a comprehensive ecological network that includes all known trophic and diverse non-trophic links among >100 coexisting species for the marine rocky intertidal community of the central Chilean coast. Our results suggest that non-trophic interactions exhibit highly nonrandom structures both alone and with respect to food web structure. The occurrence of different types of interactions, relative to all possible links, was well predicted by trophic structure and simple traits of the source and target species. In this community, competition for space and positive interactions related to habitat/refuge provisioning by sessile and/or basal species were by far the most abundant non-trophic interactions. If these patterns are orroborated in other ecosystems, they may suggest potentially important dynamic constraints on the combined architecture of trophic and non-trophic interactions. The nonrandom patterning of non-trophic interactions suggests a path forward for developing a more comprehensive ecological network theory to predict the functioning and resilience of ecological communities.

  17. Non-Chemical Distant Cellular Interactions as a potential confounder of Cell Biology Experiments

    Directory of Open Access Journals (Sweden)

    Ashkan eFarhadi

    2014-10-01

    Full Text Available Distant cells can communicate with each other through a variety of methods. Two such methods involve electrical and/or chemical mechanisms. Non-chemical, distant cellular interactions may be another method of communication that cells can use to modify the behavior of other cells that are mechanically separated. Moreover, non-chemical, distant cellular interactions may explain some cases of confounding effects in Cell Biology experiments. In this article, we review non-chemical, distant cellular interactions studies to try to shed light on the mechanisms in this highly unconventional field of cell biology. Despite the existence of several theories that try to explain the mechanism of non-chemical, distant cellular interactions, this phenomenon is still speculative. Among candidate mechanisms, electromagnetic waves appear to have the most experimental support. In this brief article, we try to answer a few key questions that may further clarify this mechanism.

  18. Stability of stationary states of non-local equations with singular interaction potentials

    KAUST Repository

    Fellner, Klemens

    2011-04-01

    We study the large-time behaviour of a non-local evolution equation for the density of particles or individuals subject to an external and an interaction potential. In particular, we consider interaction potentials which are singular in the sense that their first derivative is discontinuous at the origin.For locally attractive singular interaction potentials we prove under a linear stability condition local non-linear stability of stationary states consisting of a finite sum of Dirac masses. For singular repulsive interaction potentials we show the stability of stationary states of uniformly bounded solutions under a convexity condition.Finally, we present numerical simulations to illustrate our results. © 2010 Elsevier Ltd.

  19. Interaction between liquid droplets and heated surface

    Energy Technology Data Exchange (ETDEWEB)

    Nigmatulin, B I [Research and Engineering Centre, LWR Nuclear Plants Safety, Elektrogorsk (Russian Federation); Vasiliev, N I [Research and Engineering Centre, LWR Nuclear Plants Safety, Elektrogorsk (Russian Federation); Guguchkin, V V [Research and Engineering Centre, LWR Nuclear Plants Safety, Elektrogorsk (Russian Federation)

    1993-06-01

    In this paper, experimental methods and investigation results of interaction between droplets of different liquids and a heated surface are presented. Wetted area, contact time period and transition boundary from wetted to non-wetted interaction regimes are experimentally evaluated. A simple connection of the wetted area value and contact time period with the heat removal efficiency is shown. (orig.)

  20. Can Non-Interactive Language Input Benefit Young Second-Language Learners?

    Science.gov (United States)

    Au, Terry Kit-fong; Chan, Winnie Wailan; Cheng, Liao; Siegel, Linda S.; Tso, Ricky Van Yip

    2015-01-01

    To fully acquire a language, especially its phonology, children need linguistic input from native speakers early on. When interaction with native speakers is not always possible--e.g. for children learning a second language that is not the societal language--audios are commonly used as an affordable substitute. But does such non-interactive input…

  1. Reduction of wind power induced reserve requirements by advanced shortest-term forecasts and prediction intervals

    Energy Technology Data Exchange (ETDEWEB)

    Dobschinski, Jan; Wessel, Arne; Lange, Bernhard; Bremen, Lueder von [Fraunhofer Institut fuer Windenergie und Energiesystemtechnik (IWES), Kassel (Germany)

    2009-07-01

    In electricity systems with large penetration of wind power, the limited predictability of the wind power generation leads to an increase in reserve and balancing requirements. At first the present study concentrates on the capability of dynamic day-ahead prediction intervals to reduce the wind power induced reserve and balancing requirements. Alternatively the reduction of large forecast errors of the German wind power generation by using advanced shortest-term predictions has been evaluated in a second approach. With focus on the allocation of minute reserve power the aim is to estimate the maximal remaining uncertainty after trading activities on the intraday market. Finally both approaches were used in a case study concerning the reserve requirements induced by the total German wind power expansion in 2007. (orig.)

  2. Can OPERA help in constraining neutrino non-standard interactions?

    Energy Technology Data Exchange (ETDEWEB)

    Esteban-Pretel, A.; Valle, J.W.F. [AHEP Group, Institut de Fisica Corpuscular, C.S.I.C./Universitat de Valencia, Edificio Institutos de Paterna, Apt 22085, E-46071 Valencia (Spain); Huber, P. [Theory Division, Department of Physics, CERN, CH-1211 Geneva 23 (Switzerland); Institute for Particle, Nuclear and Astronomical Sciences, Physics Department, Virgina Tech, Blacksburg, VA 24062 (United States)], E-mail: pahuber@vt.edu

    2008-10-09

    We study how much the unique ability of the OPERA experiment to directly detect {nu}{sub {tau}} can help in probing new, non-standard contact interactions of the third family of neutrinos. We perform a combined analysis of future, high-statistics MINOS and OPERA data. For the case of non-standard interactions in {nu}{sub {mu}} to {nu}{sub e} transitions we also include the impact of possible Double Chooz data. In all cases we find that the {nu}{sub {tau}} sample of OPERA is too small to be statistically significant, even if one doubles the nominal exposure of OPERA to 9x10{sup 19} pot. OPERA's real benefit for this measurement lies in its very high neutrino energy and hence very different L/E compared to MINOS.

  3. Interactive use of communication by verbal and non-verbal autistic children.

    Science.gov (United States)

    Amato, Cibelle Albuquerque de la Higuera; Fernandes, Fernanda Dreux Miranda

    2010-01-01

    Communication of autistic children. To assess the communication functionality of verbal and non-verbal children of the autistic spectrum and to identify possible associations amongst the groups. Subjects were 20 children of the autistic spectrum divided into two groups: V with 10 verbal children and NV with 10 non-verbal children with ages varying between 2y10m and 10y6m. All subjects were video recorded during 30 minutes of spontaneous interaction with their mothers. The samples were analyzed according to the functional communicative profile and comparisons within and between groups were conducted. Data referring to the occupation of communicative space suggest that there is an even balance between each child and his mother. The number of communicative acts per minute shows a clear difference between verbal and non-verbal children. Both verbal and non-verbal children use mostly the gestual communicative mean in their interactions. Data about the use of interpersonal communicative functions point out to the autistic children's great interactive impairment. The characterization of the functional communicative profile proposed in this study confirmed the autistic children's difficulties with interpersonal communication and that these difficulties do not depend on the preferred communicative mean.

  4. The period between exfoliation of primary teeth and the emergence of permanent successors.

    Science.gov (United States)

    Nyström, M; Peck, L

    1989-02-01

    The dates of natural exfoliation of primary teeth and of clinical eruption of their successors were recorded in 141 children, a total of 660 teeth. The aim of this investigation was to study the length of the period between these two developmental events. In the mandible, the mean length of the toothless period for the central incisor was 2 weeks and that for the lateral incisors and canines 6 weeks. In the maxilla, the corresponding period was 6 weeks for the central incisor and over 4 months for the lateral incisor and the canine. The mean length of the toothless period was shortest, 0-6 days, between the primary molars and the succeeding premolars. Individual variation was great. No difference was detected between the sexes. In some cases the length of the toothless period for the maxillary lateral incisors and for the canines in both jaws exceeded one year. This was associated with crowding, which caused the premature loss of primary teeth.

  5. Status of non-standard neutrino interactions

    International Nuclear Information System (INIS)

    Ohlsson, Tommy

    2013-01-01

    The phenomenon of neutrino oscillations has been established as the leading mechanism behind neutrino flavor transitions, providing solid experimental evidence that neutrinos are massive and lepton flavors are mixed. Here we review sub-leading effects in neutrino flavor transitions known as non-standard neutrino interactions (NSIs), which is currently the most explored description for effects beyond the standard paradigm of neutrino oscillations. In particular, we report on the phenomenology of NSIs and their experimental and phenomenological bounds as well as an outlook for future sensitivity and discovery reach. (review article)

  6. Constraints on Non-Standard Contributions to the Charged-Current Interactions

    CERN Document Server

    Hagiwara, K; Hagiwara, Kaoru; Matsumoto, Seiji

    1998-01-01

    The success of the quantum level predictions of the Standard Model on the $Z$ boson properties, on $\\mw$ and on $\\mt$, which makes use of the muon lifetime as an input, implies a stringent constraint on new physics contributions to the $V-A$ charged-current interactions among leptons. Observed unitarity of the CKM matrix elements then implies constraints on non-standard contributions to the lepton-quark charged-current interactions. By using the recent electroweak data as inputs, we find the 95% CL limits for the corresponding contact interactions: $\\Lambda_{CC,+}^{\\ell\\ell}>7.5$ TeV and the lepton-quark contact interactions.

  7. Fourier analysis in dynamic non periodic phenomena in nuclear medicine

    International Nuclear Information System (INIS)

    Constantinesco, A.; Lallot, C.

    1984-01-01

    The success of Fourier analysis in assessing cardiac function has led us to investigate other possible uses of this technique. We show that phase analysis applied to dynamic non periodic activity changes gives useful parametric functional images. The phase image is comparable to a transit time image, the amplitude image is comparable to the maximum variations of activity and the mean image corresponds to a normalized sum of images. Exemples of this powerful application of Fourier analysis are discussed [fr

  8. Non Standard Finite Difference Scheme for Mutualistic Interaction Description

    OpenAIRE

    Gabbriellini, Gianluca

    2012-01-01

    One of the more interesting themes of the mathematical ecology is the description of the mutualistic interaction between two interacting species. Based on continuous-time model developed by Holland and DeAngelis 2009 for consumer-resource mutualism description, this work deals with the application of the Mickens Non Standard Finite Difference method to transform the continuous-time scheme into a discrete-time one. It has been proved that the Mickens scheme is dynamically consistent with the o...

  9. Faktor-Faktor yang Mempengaruhi Financial Sustainability Ratio pada Bank Umum Swast Nasional Non Devisa Periode 1995-2005

    Directory of Open Access Journals (Sweden)

    Luciana Spica Almilia

    2009-01-01

    Full Text Available This study is aimed to test the consistency of time period model, whether the information that previously affects today’s performance can be used to predict the performance in the future, and how the consistency of Indonesia banking financial prediction model formulation equation in order to detect bank condition and performance in the period of pre-economic crisis (1995-1996, during economic crisis (1997-1999 or post-economic crisis (2000-2005 is since bank condition and health is the interest of all relevant parties namely bank owner and manager, customers, Bank Indonesia in its capacity as the supervisor and builder, and the government. The samples are Non Foreign Exchange National Private Banks listed in Indonesian Banking Directory during the period after economic crisis in 1995 – 2005 and Indonesian Financial Economic Statistics Monthly Statement for economic macro indicator. The sampling is performed by means of purposive method (purposive sampling. Dependent Variable in this study is Financial Sustainability Ratio and independent variable in this study is Capital Adequacy Ratio, Non Performing Loan, Return On Assets, Operational Cost Ratio to Operational Income, Loan to Deposit Ratio, Money Supply Sensitivity, General Customer Price Index Sensitivity and SBI Interest Rate Sensitivity. The result of this study shows that model financial sustainability ratio did not have structural stabilization in 1999 – 2005. Abstract in Bahasa Indonesia: Penelitian ini betujuan untuk menguji konsistensi model prediksi kinerja keuangan pada Bank Umum Swasta Nasional Non Devisa periode 1995-2005. Variabel-variabel yang digunakan dalam penelitian ini adalah kinerja keuangan Bank Umum Swasta Nasional Non Devisa yang diproksikan melalui Financial Sustainability Ratio (FSR. Sampel yang terpilih dalam penelitian ini dengan metode purposive sampling berjumlah 28 bank umum swasta nasional non devisa yang terdaftar di direktori Bank Indonesia selama tahun

  10. Evolution of periodicity in periodical cicadas.

    Science.gov (United States)

    Ito, Hiromu; Kakishima, Satoshi; Uehara, Takashi; Morita, Satoru; Koyama, Takuya; Sota, Teiji; Cooley, John R; Yoshimura, Jin

    2015-09-14

    Periodical cicadas (Magicicada spp.) in the USA are famous for their unique prime-numbered life cycles of 13 and 17 years and their nearly perfectly synchronized mass emergences. Because almost all known species of cicada are non-periodical, periodicity is assumed to be a derived state. A leading hypothesis for the evolution of periodicity in Magicicada implicates the decline in average temperature during glacial periods. During the evolution of periodicity, the determinant of maturation in ancestral cicadas is hypothesized to have switched from size dependence to time (period) dependence. The selection for the prime-numbered cycles should have taken place only after the fixation of periodicity. Here, we build an individual-based model of cicadas under conditions of climatic cooling to explore the fixation of periodicity. In our model, under cold environments, extremely long juvenile stages lead to extremely low adult densities, limiting mating opportunities and favouring the evolution of synchronized emergence. Our results indicate that these changes, which were triggered by glacial cooling, could have led to the fixation of periodicity in the non-periodical ancestors.

  11. NASCENT: an automatic protein interaction network generation tool for non-model organisms.

    Science.gov (United States)

    Banky, Daniel; Ordog, Rafael; Grolmusz, Vince

    2009-04-24

    Large quantity of reliable protein interaction data are available for model organisms in public depositories (e.g., MINT, DIP, HPRD, INTERACT). Most data correspond to experiments with the proteins of Saccharomyces cerevisiae, Drosophila melanogaster, Homo sapiens, Caenorhabditis elegans, Escherichia coli and Mus musculus. For other important organisms the data availability is poor or non-existent. Here we present NASCENT, a completely automatic web-based tool and also a downloadable Java program, capable of modeling and generating protein interaction networks even for non-model organisms. The tool performs protein interaction network modeling through gene-name mapping, and outputs the resulting network in graphical form and also in computer-readable graph-forms, directly applicable by popular network modeling software. http://nascent.pitgroup.org.

  12. Minimum curvilinearity to enhance topological prediction of protein interactions by network embedding

    KAUST Repository

    Cannistraci, Carlo

    2013-06-21

    Motivation: Most functions within the cell emerge thanks to protein-protein interactions (PPIs), yet experimental determination of PPIs is both expensive and time-consuming. PPI networks present significant levels of noise and incompleteness. Predicting interactions using only PPI-network topology (topological prediction) is difficult but essential when prior biological knowledge is absent or unreliable.Methods: Network embedding emphasizes the relations between network proteins embedded in a low-dimensional space, in which protein pairs that are closer to each other represent good candidate interactions. To achieve network denoising, which boosts prediction performance, we first applied minimum curvilinear embedding (MCE), and then adopted shortest path (SP) in the reduced space to assign likelihood scores to candidate interactions. Furthermore, we introduce (i) a new valid variation of MCE, named non-centred MCE (ncMCE); (ii) two automatic strategies for selecting the appropriate embedding dimension; and (iii) two new randomized procedures for evaluating predictions.Results: We compared our method against several unsupervised and supervisedly tuned embedding approaches and node neighbourhood techniques. Despite its computational simplicity, ncMCE-SP was the overall leader, outperforming the current methods in topological link prediction.Conclusion: Minimum curvilinearity is a valuable non-linear framework that we successfully applied to the embedding of protein networks for the unsupervised prediction of novel PPIs. The rationale for our approach is that biological and evolutionary information is imprinted in the non-linear patterns hidden behind the protein network topology, and can be exploited for predicting new protein links. The predicted PPIs represent good candidates for testing in high-throughput experiments or for exploitation in systems biology tools such as those used for network-based inference and prediction of disease-related functional modules. The

  13. Non-linear vibrational modes in biomolecules: A periodic orbits description

    International Nuclear Information System (INIS)

    Kampanarakis, Alexandros; Farantos, Stavros C.; Daskalakis, Vangelis; Varotsis, Constantinos

    2012-01-01

    Graphical abstract: Vibrational frequency shifts in Fe IV = O species of the active site of cytochrome c oxidase are attributed to changes in the surrounding Coulomb field. Periodic orbits analysis assists to find the most anharmonic modes in model biomolecules. Highlights: ► Periodic orbits are extended to multidimensional potentials of biomolecules. ► Highly anharmonic vibrational modes and center-saddle bifurcations are detected. ► Vibrational frequencies shifts in Oxoferryl species of CcO are observed. - Abstract: The vibrational harmonic normal modes of a molecule, which are valid at energies close to an equilibrium point (a minimum, maximum or saddle of the potential energy surface), are extended by periodic orbits to high energies where anharmonicity and coupling of the degrees of freedom are significant. In this way the assignment of the spectra, and thus the extraction of dynamics in highly excited molecules, can be obtained. New vibrational modes emanating from bifurcations of periodic orbits and long living localized trajectories signal the birth and localization of new quantum states. In this article we review and further study non-linear vibrational modes for model biomolecules such as alanine dipeptide and the active site in the oxoferryl oxidation state of the enzyme cytochrome c oxidase. We locate periodic orbits which exhibit high anhamonicity and lead to center-saddle bifurcations. These modes are associated to an isomerization process in alanine dipeptide and to frequency shifts in the oxoferryl observed by modifying the Coulomb field around the Imidazole–Fe IV = O species.

  14. A non-linear theory of strong interactions

    International Nuclear Information System (INIS)

    Skyrme, T.H.R.

    1994-01-01

    A non-linear theory of mesons, nucleons and hyperons is proposed. The three independent fields of the usual symmetrical pseudo-scalar pion field are replaced by the three directions of a four-component field vector of constant length, conceived in an Euclidean four-dimensional isotopic spin space. This length provides the universal scaling factor, all other constants being dimensionless; the mass of the meson field is generated by a φ 4 term; this destroys the continuous rotation group in the iso-space, leaving a 'cubic' symmetry group. Classification of states by this group introduces quantum numbers corresponding to isotopic spin and to 'strangeness'; one consequences is that, at least in elementary interactions, charge is only conserved module 4. Furthermore, particle states have not a well-defined parity, but parity is effectively conserved for meson-nucleon interactions. A simplified model, using only two dimensions of space and iso-space, is considered further; the non-linear meson field has solutions with particle character, and an indication is given of the way in which the particle field variables might be introduced as collective co-ordinates describing the dynamics of these particular solutions of the meson field equations, suggesting a unified theory based on the meson field alone. (author). 7 refs

  15. Period doubling on a non-neutral magnetized electron beam

    International Nuclear Information System (INIS)

    Boswell, R.W.

    1984-01-01

    Low frequency oscillations on a non-neutral magnetized electron beam of very low density are investigated. A perturbation analysis of the slow mode of the rigid rotator equilibrium is developed to illustrate the nature of large amplitude fundamental mode oscillations. The results of this theoretical analysis show two important characteristics: firstly, as the perturbation amplitude is increasedthe waveform ceases to be purely sinusoidal and shows period doubling. Secondly, above a certain threshold, all harmonics of the wave grow and the wave breaks. The results of the former are compared with a simple electron beam experiment and are found to be in good qualitative agreement

  16. Non-Almost Periodicity of Parallel Transports for Homogeneous Connections

    International Nuclear Information System (INIS)

    Brunnemann, Johannes; Fleischhack, Christian

    2012-01-01

    Let A be the affine space of all connections in an SU(2) principal fibre bundle over ℝ 3 . The set of homogeneous isotropic connections forms a line l in A. We prove that the parallel transports for general, non-straight paths in the base manifold do not depend almost periodically on l. Consequently, the embedding l ↪ A does not continuously extend to an embedding l-bar ↪ A-bar of the respective compactifications. Here, the Bohr compactification l-bar corresponds to the configuration space of homogeneous isotropic loop quantum cosmology and A-bar to that of loop quantum gravity. Analogous results are given for the anisotropic case.

  17. Non-additive non-interacting kinetic energy of rare gas dimers

    Science.gov (United States)

    Jiang, Kaili; Nafziger, Jonathan; Wasserman, Adam

    2018-03-01

    Approximations of the non-additive non-interacting kinetic energy (NAKE) as an explicit functional of the density are the basis of several electronic structure methods that provide improved computational efficiency over standard Kohn-Sham calculations. However, within most fragment-based formalisms, there is no unique exact NAKE, making it difficult to develop general, robust approximations for it. When adjustments are made to the embedding formalisms to guarantee uniqueness, approximate functionals may be more meaningfully compared to the exact unique NAKE. We use numerically accurate inversions to study the exact NAKE of several rare-gas dimers within partition density functional theory, a method that provides the uniqueness for the exact NAKE. We find that the NAKE decreases nearly exponentially with atomic separation for the rare-gas dimers. We compute the logarithmic derivative of the NAKE with respect to the bond length for our numerically accurate inversions as well as for several approximate NAKE functionals. We show that standard approximate NAKE functionals do not reproduce the correct behavior for this logarithmic derivative and propose two new NAKE functionals that do. The first of these is based on a re-parametrization of a conjoint Perdew-Burke-Ernzerhof (PBE) functional. The second is a simple, physically motivated non-decomposable NAKE functional that matches the asymptotic decay constant without fitting.

  18. THE VERY SHORT PERIOD M DWARF BINARY SDSS J001641-000925

    Energy Technology Data Exchange (ETDEWEB)

    Davenport, James R. A.; Becker, Andrew C.; Hawley, Suzanne L.; Gunning, Heather C.; Munshi, Ferah A.; Albright, Meagan [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); West, Andrew A. [Astronomy Department, Boston University, 725 Commonwealth Avenue, Boston, MA 02215 (United States); Bochanski, John J. [Astronomy and Astrophysics Department, Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States); Holtzman, Jon [Department of Astronomy, New Mexico State University, Box 30001, Las Cruces, NM 88003 (United States); Hilton, Eric J., E-mail: jrad@astro.washington.edu [Department of Geology and Geophysics and Institute for Astronomy, University of Hawaii at Manoa, Honolulu, HI 96822 (United States)

    2013-02-10

    We present follow-up observations and analysis of the recently discovered short period low-mass eclipsing binary, SDSS J001641-000925. With an orbital period of 0.19856 days, this system has one of the shortest known periods for an M dwarf binary system. Medium-resolution spectroscopy and multi-band photometry for the system are presented. Markov Chain Monte Carlo modeling of the light curves and radial velocities yields estimated masses for the stars of M {sub 1} = 0.54 {+-} 0.07 M {sub Sun} and M {sub 2} = 0.34 {+-} 0.04 M {sub Sun }, and radii of R {sub 1} = 0.68 {+-} 0.03 R {sub Sun} and R {sub 2} = 0.58 {+-} 0.03 R {sub Sun }, respectively. This solution places both components above the critical Roche overfill limit, providing strong evidence that SDSS J001641-000925 is the first verified M-dwarf contact binary system. Within the follow-up spectroscopy we find signatures of non-solid body rotation velocities, which we interpret as evidence for mass transfer or loss within the system. In addition, our photometry samples the system over nine years, and we find strong evidence for period decay at the rate of P-dot {approx} 8 s yr{sup -1}. Both of these signatures raise the intriguing possibility that the system is in over-contact, and actively losing angular momentum, likely through mass loss. This places SDSS J001641-000925 as not just the first M-dwarf over-contact binary, but one of the few systems of any spectral type known to be actively undergoing coalescence. Further study of SDSS J001641-000925 is ongoing to verify the nature of the system, which may prove to be a unique astrophysical laboratory.

  19. Non abelian Chern-Simons topological coupling from self-interaction

    International Nuclear Information System (INIS)

    Aragone, C.; Stephany, R.J.E.

    1986-01-01

    It is shown that the self-interaction mechanism drives in one step the topologically coupled-Maxwell-second rank antisymmetric tensor system into the Chern-Simons coupled -non abelian- (second rank) antisymmetric tensor action. Only one step is required to saturate the process because the action for the initial Maxwell-antisymmetric tensor system is given in its first-order form. The self-interaction mechanism works both for the original Chapline-Manton form of the action and for the dual form. (Author) [pt

  20. Interactive neonatal gastrointestinal magnetic resonance imaging using fruit juice as an oral contrast media

    International Nuclear Information System (INIS)

    Arthurs, Owen J; Graves, Martin J; Edwards, Andrea D; Joubert, Ilse; Set, Pat AK; Lomas, David J

    2014-01-01

    The objective was to evaluate the use of fruit juice with an interactive inversion recovery (IR) MR pulse sequence to visualise the gastrointestinal tract. We investigated the relaxation properties of 12 different natural fruit juices in vitro, to identify which could be used as oral contrast. We then describe our initial experience using an interactive MR pulse sequence to allow optimal visualisation after administering pineapple juice orally, and suppressing pre-existing bowel fluid contents, with variable TI in three adult and one child volunteer. Pineapple juice (PJ) had both the shortest T 1 (243 ms) and shortest T 2 (48 ms) of the fruit juices tested. Optimal signal differentiation between pre-existing bowel contents and oral PJ administration was obtained with TIs of between 900 and 1100 ms. The use of an inversion recovery preparation allowed long T 1 pre-existing bowel contents to be suppressed whilst the short T 1 of fruit juice acts as a positive contrast medium. Pineapple juice could be used as oral contrast agent for neonatal gastrointestinal magnetic resonance imaging

  1. Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

    Energy Technology Data Exchange (ETDEWEB)

    Perelomova, Anna [Gdansk University of Technology, Faculty of Applied Physics and Mathematics, ul. Narutowicza 11/12, 80-952 Gdansk (Poland)]. E-mail: anpe@mif.pg.gda.pl

    2006-08-28

    The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,{rho}) and caloric e(p,{rho}) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed.

  2. Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

    Science.gov (United States)

    Perelomova, Anna

    2006-08-01

    The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,ρ) and caloric e(p,ρ) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed.

  3. Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

    International Nuclear Information System (INIS)

    Perelomova, Anna

    2006-01-01

    The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,ρ) and caloric e(p,ρ) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed

  4. Instabilities in fluid layers and in reaction-diffusion systems: Steady states, time-periodic solutions, non-periodic attractors, and related convective and otherwise non-linear phenomena

    Energy Technology Data Exchange (ETDEWEB)

    Garcia Velarde, M

    1977-07-01

    Thermo convective instabilities in horizontal fluid layers are discussed with emphasis on the Rayleigh-Bernard model problem. Steady solutions and time-dependent phenomena (relaxation oscillations and transition to turbulence) are studied within the nonlinear Boussinesq-Oberbeck approximation. Homogeneous steady solutions, limit cycles, and inhomogeneous (ordered) spatial structures are also studied in simple reaction-diffusion systems. Lastly, the non-periodic attractor that appears at large Rayleigh numbers in the truncated Boussinesq-Oberbeck model of Lorenz, is constructed, and a discussion of turbulent behavior is given. (Author) 105 refs.

  5. Instabilities in fluid layers and in reaction-diffusion systems: Steady states, time-periodic solutions, non-periodic attractors, and related convective and otherwise non-linear phenomena

    International Nuclear Information System (INIS)

    Garcia Velarde, M.

    1977-01-01

    Thermoconvective instabilities in horizontal fluid layers are discussed with emphasis on the Rayleigh-Benard model problem. Steady solutions and time-dependent phenomena (relaxation oscillations and transition to turbulence) are studied within the nonlinear Boussinesq-Oberbeck approximation. Homogeneous steady solutions, limit cycles, and inhomogeneous (ordered) spatial structures are also studied in simple reaction-diffusion systems. Lastly, the non-periodic attractor that appears at large Rayleigh numbers in the truncated Boussinesq-Oberbeck model of Lorenz, is constructed, and a discussion of turbulent behavior is given. (author) [es

  6. Instabilities in fluid layers and in reaction-diffusion systems: Steady states, time-periodic solutions, non-periodic attractors, and related convective and otherwise non-linear phenomena

    International Nuclear Information System (INIS)

    Garcia Velarde, M.

    1977-01-01

    Thermo convective instabilities in horizontal fluid layers are discussed with emphasis on the Rayleigh-Bernard model problem. Steady solutions and time-dependent phenomena (relaxation oscillations and transition to turbulence) are studied within the nonlinear Boussinesq-Oberbeck approximation. Homogeneous steady solutions, limit cycles, and inhomogeneous (ordered) spatial structures are also studied in simple reaction-diffusion systems. Lastly, the non-periodic attractor that appears at large Rayleigh numbers in the truncated Boussinesq-Oberbeck model of Lorenz, is constructed, and a discussion of turbulent behavior is given. (Author) 105 refs

  7. Non-Abelian monopole in the parameter space of point-like interactions

    International Nuclear Information System (INIS)

    Ohya, Satoshi

    2014-01-01

    We study non-Abelian geometric phase in N=2 supersymmetric quantum mechanics for a free particle on a circle with two point-like interactions at antipodal points. We show that non-Abelian Berry’s connection is that of SU(2) magnetic monopole discovered by Moody, Shapere and Wilczek in the context of adiabatic decoupling limit of diatomic molecule. - Highlights: • Supersymmetric quantum mechanics is an ideal playground for studying geometric phase. • We determine the parameter space of supersymmetric point-like interactions. • Berry’s connection is given by a Wu–Yang-like magnetic monopole in SU(2) Yang–Mills

  8. Non-potential interactions and the origin of masses of elementary particles

    International Nuclear Information System (INIS)

    Sun, J.

    1982-01-01

    We propose a fundamental assumption on internal states of particles. It follows from the fundamental assumption that: (1) the constituents of particles become non-particle objects; and (2) there appear naturally non-potential interactions. This non-potential interaction leads to a series of interesting results, one of which is that it yields the origin of masses of elementary particles. All mass values are given by the theory without pre-assumed mass values of the constituents (except the rest mass of the electron; mass is a physical quantity which appears only in particles but not in their constituents). The theoretically calculated mass values are in excellent agreement with the experimental values. In all calculations, only one constant b = 0.99935867 is introduced (bc being the speed of internal motion)

  9. Protein-protein interaction network-based detection of functionally similar proteins within species.

    Science.gov (United States)

    Song, Baoxing; Wang, Fen; Guo, Yang; Sang, Qing; Liu, Min; Li, Dengyun; Fang, Wei; Zhang, Deli

    2012-07-01

    Although functionally similar proteins across species have been widely studied, functionally similar proteins within species showing low sequence similarity have not been examined in detail. Identification of these proteins is of significant importance for understanding biological functions, evolution of protein families, progression of co-evolution, and convergent evolution and others which cannot be obtained by detection of functionally similar proteins across species. Here, we explored a method of detecting functionally similar proteins within species based on graph theory. After denoting protein-protein interaction networks using graphs, we split the graphs into subgraphs using the 1-hop method. Proteins with functional similarities in a species were detected using a method of modified shortest path to compare these subgraphs and to find the eligible optimal results. Using seven protein-protein interaction networks and this method, some functionally similar proteins with low sequence similarity that cannot detected by sequence alignment were identified. By analyzing the results, we found that, sometimes, it is difficult to separate homologous from convergent evolution. Evaluation of the performance of our method by gene ontology term overlap showed that the precision of our method was excellent. Copyright © 2012 Wiley Periodicals, Inc.

  10. Improving LMA predictions with non standard interactions

    CERN Document Server

    Das, C R

    2010-01-01

    It has been known for some time that the well established LMA solution to the observed solar neutrino deficit fails to predict a flat energy spectrum for SuperKamiokande as opposed to what the data indicates. It also leads to a Chlorine rate which appears to be too high as compared to the data. We investigate the possible solution to these inconsistencies with non standard neutrino interactions, assuming that they come as extra contributions to the $\

  11. The role of oxytocin in mothers' theory of mind and interactive behavior during the perinatal period.

    Science.gov (United States)

    MacKinnon, Anna L; Gold, Ian; Feeley, Nancy; Hayton, Barbara; Carter, C Sue; Zelkowitz, Phyllis

    2014-10-01

    The present longitudinal study examined the relations between plasma oxytocin, theory of mind, and maternal interactive behavior during the perinatal period. A community sample of women was assessed at 12-14 weeks gestation, 32-34 weeks gestation, and 7-9 weeks postpartum. Oxytocin during late pregnancy was significantly positively correlated with a measure of theory of mind, and predicted theory of mind ability after controlling for parity, maternal education, prenatal psychosocial risk, and general anxiety, measured during the first trimester. Theory of mind was associated with less remote and less depressive maternal interactive behavior. Oxytocin, across all time points, was not directly related to maternal interactive behavior. However, there was a significant indirect effect of oxytocin during late pregnancy on depressive maternal behavior via theory of mind ability. These preliminary findings suggest that changes in the oxytocinergic system during the perinatal period may contribute to the awareness of social cues, which in turn plays a role in maternal interactive behavior. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Electro-osmosis over inhomogeneously charged surfaces in presence of non-electrostatic ion-ion interactions

    Science.gov (United States)

    Ghosh, Uddipta; Chakraborty, Suman

    2016-06-01

    In this study, we attempt to bring out a generalized formulation for electro-osmotic flows over inhomogeneously charged surfaces in presence of non-electrostatic ion-ion interactions. To this end, we start with modified electro-chemical potential of the individual species and subsequently use it to derive modified Nernst-Planck equation accounting for the ionic fluxes generated because of the presence of non-electrostatic potential. We establish what we refer to as the Poisson-Helmholtz-Nernst-Planck equations, coupled with the Navier-Stokes equations, to describe the complete transport process. Our analysis shows that the presence of non-electrostatic interactions between the ions results in an excess body force on the fluid, and modifies the osmotic pressure as well, which has hitherto remained unexplored. We further apply our analysis to a simple geometry, in an effort to work out the Smoluchowski slip velocity for thin electrical double layer limits. To this end, we employ singular perturbation and develop a general framework for the asymptotic analysis. Our calculations reveal that the final expression for slip velocity remains the same as that without accounting for non-electrostatic interactions. However, the presence of non-electrostatic interactions along with ion specificity can significantly change the quantitative behavior of Smoluchowski slip velocity. We subsequently demonstrate that the presence of non-electrostatic interactions may significantly alter the effective interfacial potential, also termed as the "Zeta potential." Our analysis can potentially act as a guide towards the prediction and possibly quantitative determination of the implications associated with the existence of non-electrostatic potential, in an electrokinetic transport process.

  13. Long-lived periodic revivals of coherence in an interacting Bose-Einstein condensate

    Energy Technology Data Exchange (ETDEWEB)

    Egorov, M.; Ivannikov, V.; Opanchuk, B.; Drummond, P.; Hall, B. V.; Sidorov, A. I. [ARC Centre of Excellence for Quantum-Atom Optics and Centre for Atom Optics and Ultrafast Spectroscopy, Swinburne University of Technology, Melbourne 3122 (Australia); Anderson, R. P. [ARC Centre of Excellence for Quantum-Atom Optics and Centre for Atom Optics and Ultrafast Spectroscopy, Swinburne University of Technology, Melbourne 3122 (Australia); School of Physics, Monash University, Victoria 3800 (Australia)

    2011-08-15

    We observe the coherence of an interacting two-component Bose-Einstein condensate (BEC) surviving for seconds in a trapped Ramsey interferometer. Mean-field-driven collective oscillations of two components lead to periodic dephasing and rephasing of condensate wave functions with a slow decay of the interference fringe visibility. We apply spin echo synchronous with the self-rephasing of the condensate to reduce the influence of state-dependent atom losses, significantly enhancing the visibility up to 0.75 at the evolution time of 1.5 s. Mean-field theory consistently predicts higher visibility than experimentally observed values. We quantify the effects of classical and quantum noise and infer a coherence time of 2.8 s for a trapped condensate of 5.5x10{sup 4} interacting atoms.

  14. Non-formal Learning through Ludic Engagement within Interactive Environments

    DEFF Research Database (Denmark)

    Petersson, Eva

    Adaptive responsive environments that encourage interaction for children with severe disabilities offer a distinct potential for play and learning in rehabilitation. Physical training and therapy for these children is often enduring, tedious, and boring through repetition – and this is often...... the case for both the child and the facilitator/therapist. Despite this, little is yet known about how the utilization of empowering technology influences the users’ communication and learning. The aim of this thesis is twofold: to contribute to the understanding of the role of action and interaction...... in the learning involved when people with different abilities are using interactive environments, and to make a contribution to the research field by concluding at tentative generalizations on design for non-formal learning in interactive environments.      The thesis consists of seven studies which analyze...

  15. Directed selective-tunneling of bosons with periodically modulated interaction

    International Nuclear Information System (INIS)

    Lu, Gengbiao; Fu, Li-Bin; Hai, Wenhua; Zou, Mingliang; Guo, Yu

    2015-01-01

    We study the tunneling dynamics of bosons with periodically modulated interaction held in a triple-well potential. In high-frequency approximation, we derive a set of reduced coupled equations and the corresponding Floquet solutions are obtained. Based on the analytical results and their numerical correspondence, the directed selective-tunneling effect of a single atom is demonstrated when all bosons are prepared in middle well initially. A scheme for separating a single atom from N bosons is presented, in which the atom can be trapped in right or left well by adjusting the modulation strength. - Highlights: • The Floquet solutions in a modulating triple-well are obtained analytically. • The directed selective-tunneling effect of a single atom is demonstrated. • We present a manipulation scheme for separating a single atom from N bosons

  16. Higher pressure periodic CO/sub 2/ laser with non-self-sustaining discharge and UV ionization

    Energy Technology Data Exchange (ETDEWEB)

    Muratov, E A; Pismennyi, V D; Rakhimov, A T

    1979-02-01

    Stimulated emission was achieved in a CO/sub 2/ laser operating at 250 torr excited by a periodic non-self-sustaining discharge controlled by a spark source of UV radiation. Use of a UV source operating in periodic pulse regime is shown to permit quasicontinuous operation of the laser with characteristic radiating times up to several hundred microseconds.

  17. Integration and visualization of non-coding RNA and protein interaction networks

    OpenAIRE

    Junge, Alexander; Refsgaard, Jan Christian; Garde, Christian; Pan, Xiaoyong; Santos Delgado, Alberto; Anthon, Christian; Alkan, Ferhat; von Mering, Christian; Workman, Christopher; Jensen, Lars Juhl; Gorodkin, Jan

    2015-01-01

    Non-coding RNAs (ncRNAs) fulfill a diverse set of biological functions relying on interactions with other molecular entities. The advent of new experimental and computational approaches makes it possible to study ncRNAs and their associations on an unprecedented scale. We present RAIN (RNA Association and Interaction Networks) - a database that combines ncRNA-ncRNA, ncRNA-mRNA and ncRNA-protein interactions with large-scale protein association networks available in the STRING database. By int...

  18. On the stability, the periodic solutions and the resolution of certain types of non linear equations, and of non linearly coupled systems of these equations, appearing in betatronic oscillations

    International Nuclear Information System (INIS)

    Valat, J.

    1960-12-01

    Universal stability diagrams have been calculated and experimentally checked for Hill-Meissner type equations with square-wave coefficients. The study of these equations in the phase-plane has then made it possible to extend the periodic solution calculations to the case of non-linear differential equations with periodic square-wave coefficients. This theory has been checked experimentally. For non-linear coupled systems with constant coefficients, a search was first made for solutions giving an algebraic motion. The elliptical and Fuchs's functions solve such motions. The study of non-algebraic motions is more delicate, apart from the study of nonlinear Lissajous's motions. A functional analysis shows that it is possible however in certain cases to decouple the system and to find general solutions. For non-linear coupled systems with periodic square-wave coefficients it is then possible to calculate the conditions leading to periodic solutions, if the two non-linear associated systems with constant coefficients fall into one of the categories of the above paragraph. (author) [fr

  19. More about the comparison of local and non-local NN interaction models

    International Nuclear Information System (INIS)

    Amghar, A.; Desplanques, B.

    2003-01-01

    The effect of non-locality in the NN interaction with an off-energy shell character has been studied in the past in relation with the possibility that some models could be approximately phase-shifts equivalent. This work is extended to a non-locality implying terms that involve an anticommutator with the operator p 2 . It includes both scalar and tensor components. The most recent 'high accuracy' models are considered in the analysis. After studying the deuteron wave functions, electromagnetic properties of various models are compared with the idea that these ones differ by their non-locality but are equivalent up to a unitary transformation. It is found that the extra non-local tensor interaction considered in this work tends to re-enforce the role of the term considered in previous works, allowing one to explain almost completely the difference in the deuteron D-state probabilities evidenced by the comparison of the Bonn-QB and Paris models for instance. Conclusions for the effect of the non-local scalar interaction are not so clear. In many cases, it was found that these terms could explain part of the differences that the comparison of predictions for various models evidences but cases where they could not were also found. Some of these last ones have been analyzed in order to pointing out the origin of the failure

  20. Communication Patterns in Adult-Infant Interactions in Western and Non-Western Cultures.

    Science.gov (United States)

    Keller, Heidi; And Others

    1988-01-01

    Analyzes the early communication structure in adult-child interactions with two- to six-month old babies in Western (West Germany, Greece) and non-Western (Yanomami, Trobriand) societies. Discusses universal international verbal and non-verbal structures reflecting intuitive parenting programs. (FMW)

  1. 24 CFR 58.14 - Interaction with State, Federal and non-Federal entities.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Interaction with State, Federal and non-Federal entities. 58.14 Section 58.14 Housing and Urban Development Office of the Secretary... ENVIRONMENTAL RESPONSIBILITIES General Policy: Responsibilities of Responsible Entities § 58.14 Interaction with...

  2. Antineutrino Oscillations and a Search for Non-standard Interactions with the MINOS

    Energy Technology Data Exchange (ETDEWEB)

    Isvan, Zeynep [Univ. of Pittsburgh, PA (United States)

    2012-01-01

    MINOS searches for neutrino oscillations using the disappearance of muon neutrinos from the NuMI beam at Fermilab between two detectors. The Near Detector, located near the source, measures the beam composition before flavor change occurs. The energy spectrum is measured again at the Far Detector after neutrinos travel a distance. The mixing angle and mass splitting between the second and third mass states are extracted from the energy dependent difference between the spectra at the two detectors. NuMI is able to produce an antineutrino-enhanced beam as well as a neutrino-enhanced beam. Collecting data in antineutrino-mode allows the direct measurement of antineutrino oscillation parameters. From the analysis of the antineutrino mode data we measure $|\\Delta\\bar{m}^{2}_{\\text{atm}}| = 2.62^{+0.31}_{-0.28}\\times10^{-3}\\text{eV}^{2}$ and $\\sin^{2}(2\\bar{\\theta})_{23} = 0.95^{+0.10}_{-0.11}$, which is the most precise measurement of antineutrino oscillation parameters to date. A difference between neutrino and antineutrino oscillation parameters may indicate new physics involving interactions that are not part of the Standard Model, called non-standard interactions, that alter the apparent disappearance probability. Collecting data in neutrino and antineutrino mode independently allows a direct search for non-standard interactions. In this dissertation non-standard interactions are constrained by a combined analysis of neutrino and antineutrino datasets and no evidence of such interactions is found.

  3. Impact of quadratic non-linearity on the dynamics of periodic solutions of a wave equation

    International Nuclear Information System (INIS)

    Kolesov, Andrei Yu; Rozov, Nikolai Kh

    2002-01-01

    For the non-linear telegraph equation with homogeneous Dirichlet or Neumann conditions at the end-points of a finite interval the question of the existence and the stability of time-periodic solutions bifurcating from the zero equilibrium state is considered. The dynamics of these solutions under a change of the diffusion coefficient (that is, the coefficient of the second derivative with respect to the space variable) is investigated. For the Dirichlet boundary conditions it is shown that this dynamics substantially depends on the presence - or the absence - of quadratic terms in the non-linearity. More precisely, it is shown that a quadratic non-linearity results in the occurrence, under an unbounded decrease of diffusion, of an infinite sequence of bifurcations of each periodic solution. En route, the related issue of the limits of applicability of Yu.S. Kolesov's method of quasinormal forms to the construction of self-oscillations in singularly perturbed hyperbolic boundary value problems is studied

  4. Non-statistical fluctuations in fragmentation of target nuclei in high energy nuclear interactions

    International Nuclear Information System (INIS)

    Ghosh, Dipak; Ghosh, Premomoy; Ghosh, Alokananda; Roy, Jaya

    1994-01-01

    Analysis of target fragmented ''black'' particles in nuclear emulsion from high energy relativistic interactions initiated by 16 O at 2.1 GeV/nucleon and 12 C and 24 Mg at 4.5 GeV/nucleon reveal the existence of non-statistical fluctuations in the azimuthal plane of interaction. The asymmetry or the non-statistical fluctuations, while found to be independent of projectile mass or incident energy, are dependent on the excitation energy of the target nucleus. (Author)

  5. Role of short periodic orbits in quantum maps with continuous openings

    Science.gov (United States)

    Prado, Carlos A.; Carlo, Gabriel G.; Benito, R. M.; Borondo, F.

    2018-04-01

    We apply a recently developed semiclassical theory of short periodic orbits to the continuously open quantum tribaker map. In this paradigmatic system the trajectories are partially bounced back according to continuous reflectivity functions. This is relevant in many situations that include optical microresonators and more complicated boundary conditions. In a perturbative regime, the shortest periodic orbits belonging to the classical repeller of the open map—a cantor set given by a region of exactly zero reflectivity—prove to be extremely robust in supporting a set of long-lived resonances of the continuously open quantum maps. Moreover, for steplike functions a significant reduction in the number needed is obtained, similarly to the completely open situation. This happens despite a strong change in the spectral properties when compared to the discontinuous reflectivity case. In order to give a more realistic interpretation of these results we compare with a Fresnel-type reflectivity function.

  6. Species co-occurrence networks: Can they reveal trophic and non-trophic interactions in ecological communities?

    Science.gov (United States)

    Freilich, Mara A; Wieters, Evie; Broitman, Bernardo R; Marquet, Pablo A; Navarrete, Sergio A

    2018-03-01

    Co-occurrence methods are increasingly utilized in ecology to infer networks of species interactions where detailed knowledge based on empirical studies is difficult to obtain. Their use is particularly common, but not restricted to, microbial networks constructed from metagenomic analyses. In this study, we test the efficacy of this procedure by comparing an inferred network constructed using spatially intensive co-occurrence data from the rocky intertidal zone in central Chile to a well-resolved, empirically based, species interaction network from the same region. We evaluated the overlap in the information provided by each network and the extent to which there is a bias for co-occurrence data to better detect known trophic or non-trophic, positive or negative interactions. We found a poor correspondence between the co-occurrence network and the known species interactions with overall sensitivity (probability of true link detection) equal to 0.469, and specificity (true non-interaction) equal to 0.527. The ability to detect interactions varied with interaction type. Positive non-trophic interactions such as commensalism and facilitation were detected at the highest rates. These results demonstrate that co-occurrence networks do not represent classical ecological networks in which interactions are defined by direct observations or experimental manipulations. Co-occurrence networks provide information about the joint spatial effects of environmental conditions, recruitment, and, to some extent, biotic interactions, and among the latter, they tend to better detect niche-expanding positive non-trophic interactions. Detection of links (sensitivity or specificity) was not higher for well-known intertidal keystone species than for the rest of consumers in the community. Thus, as observed in previous empirical and theoretical studies, patterns of interactions in co-occurrence networks must be interpreted with caution, especially when extending interaction

  7. Survey of non-linear hydrodynamic models of type-II Cepheids

    Science.gov (United States)

    Smolec, R.

    2016-03-01

    We present a grid of non-linear convective type-II Cepheid models. The dense model grids are computed for 0.6 M⊙ and a range of metallicities ([Fe/H] = -2.0, -1.5, -1.0), and for 0.8 M⊙ ([Fe/H] = -1.5). Two sets of convective parameters are considered. The models cover the full temperature extent of the classical instability strip, but are limited in luminosity; for the most luminous models, violent pulsation leads to the decoupling of the outermost model shell. Hence, our survey reaches only the shortest period RV Tau domain. In the Hertzsprung-Russell diagram, we detect two domains in which period-doubled pulsation is possible. The first extends through the BL Her domain and low-luminosity W Vir domain (pulsation periods ˜2-6.5 d). The second domain extends at higher luminosities (W Vir domain; periods >9.5 d). Some models within these domains display period-4 pulsation. We also detect very narrow domains (˜10 K wide) in which modulation of pulsation is possible. Another interesting phenomenon we detect is double-mode pulsation in the fundamental mode and in the fourth radial overtone. Fourth overtone is a surface mode, trapped in the outer model layers. Single-mode pulsation in the fourth overtone is also possible on the hot side of the classical instability strip. The origin of the above phenomena is discussed. In particular, the role of resonances in driving different pulsation dynamics as well as in shaping the morphology of the radius variation curves is analysed.

  8. Lateral interactions and non-equilibrium in surface kinetics

    Science.gov (United States)

    Menzel, Dietrich

    2016-08-01

    Work modelling reactions between surface species frequently use Langmuir kinetics, assuming that the layer is in internal equilibrium, and that the chemical potential of adsorbates corresponds to that of an ideal gas. Coverage dependences of reacting species and of site blocking are usually treated with simple power law coverage dependences (linear in the simplest case), neglecting that lateral interactions are strong in adsorbate and co-adsorbate layers which may influence kinetics considerably. My research group has in the past investigated many co-adsorbate systems and simple reactions in them. We have collected a number of examples where strong deviations from simple coverage dependences exist, in blocking, promoting, and selecting reactions. Interactions can range from those between next neighbors to larger distances, and can be quite complex. In addition, internal equilibrium in the layer as well as equilibrium distributions over product degrees of freedom can be violated. The latter effect leads to non-equipartition of energy over molecular degrees of freedom (for products) or non-equal response to those of reactants. While such behavior can usually be described by dynamic or kinetic models, the deeper reasons require detailed theoretical analysis. Here, a selection of such cases is reviewed to exemplify these points.

  9. Globular and disordered-the non-identical twins in protein-protein interactions

    DEFF Research Database (Denmark)

    Teilum, Kaare; Olsen, Johan Gotthardt; Kragelund, Birthe Brandt

    2015-01-01

    as a strong determinant for their function. This has fostered the notion that IDP's bind with low affinity but high specificity. Here we have analyzed available detailed thermodynamic data for protein-protein interactions to put to the test if the thermodynamic profiles of IDP interactions differ from those...... of other protein-protein interactions. We find that ordered proteins and the disordered ones act as non-identical twins operating by similar principles but where the disordered proteins complexes are on average less stable by 2.5 kcal mol(-1)....

  10. Translationally invariant and non-translationally invariant empirical effective interactions

    International Nuclear Information System (INIS)

    Golin, M.; Zamick, L.

    1975-01-01

    In this work empirical deficiencies of the core-renormalized realistic effective interactions are examined and simple corrective potentials are sought. The inability of the current realistic interactions to account for the energies of isobaric analog states is noted, likewise they are unable to reproduce the changes in the single-particle energies, as one goes from one closed shell to another. It is noted that the Schiffer interaction gives better results for these gross properties and this is attributed to a combination of several facts. First, to the inclusion of long range terms in the Schiffer potential, then to the presence of relative p-state terms (l=1), in addition to the usual relative s-state terms (l=0). The strange shape of the above interaction is further attributed to the fact that it is translationally invariant whereas the theory of core-polarization yields non-translationally invariant potentials. Consequently, as a correction to the monopole deficiencies of the realistic interactions the term Vsub(mon)=ar 2 (1)r 2 (2)+r 2 (1)+β[r 4 (1)r 2 (2)r 4 (2) ] is proposed. (Auth.)

  11. Non-statistical fluctuations in fragmentation of target nuclei in high energy nuclear interactions

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, Dipak; Ghosh, Premomoy; Ghosh, Alokananda; Roy, Jaya [Jadavpur Univ., Calcutta (India)

    1994-07-01

    Analysis of target fragmented ''black'' particles in nuclear emulsion from high energy relativistic interactions initiated by [sup 16]O at 2.1 GeV/nucleon and [sup 12]C and [sup 24]Mg at 4.5 GeV/nucleon reveal the existence of non-statistical fluctuations in the azimuthal plane of interaction. The asymmetry or the non-statistical fluctuations, while found to be independent of projectile mass or incident energy, are dependent on the excitation energy of the target nucleus. (Author).

  12. Environmentally Driven Increases in Type 2 Diabetes and Obesity in Pima Indians and Non-Pimas in Mexico Over a 15-Year Period: The Maycoba Project.

    Science.gov (United States)

    Esparza-Romero, Julian; Valencia, Mauro E; Urquidez-Romero, Rene; Chaudhari, Lisa S; Hanson, Robert L; Knowler, William C; Ravussin, Eric; Bennett, Peter H; Schulz, Leslie O

    2015-11-01

    The global epidemics of type 2 diabetes and obesity have been attributed to the interaction between lifestyle changes and genetic predisposition to these diseases. We compared the prevalences of type 2 diabetes and obesity in Mexican Pima Indians, presumed to have a high genetic predisposition to these diseases, to those in their non-Pima neighbors, both of whom over a 15-year period experienced a transition from a traditional to a more modern lifestyle. Prevalence of diabetes, impaired fasting glucose, impaired glucose tolerance, and obesity in Mexican Pimas (n = 359) and non-Pima Mexicans (n = 251) were determined in 2010 using methods identical to those used in 1995. During this 15-year period, age-adjusted diabetes prevalence was unchanged in Pima men (5.8% in 1995 vs. 6.1% in 2010) yet increased in non-Pima men from 0.0 to 8.6% (P obesity increased significantly in all groups (6.6 vs. 15.7% in Pima men; 8.5 vs. 20.5% in non-Pima men; 18.9. vs 36.3% in Pima women; 29.5 vs. 42.9% in non-Pima women). Type 2 diabetes prevalence increased between 1995 and 2010 in non-Pima men, and to a lesser degree in women of both groups, but it did not increase in Pima men. Prevalence of obesity increased among Pimas and non-Pimas of both sexes. These changes occurred concomitantly with an environmental transition from a traditional to a more modernized lifestyle. © 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

  13. Description of Non-Covalent Interactions in SCC-DFTB Methods

    Czech Academy of Sciences Publication Activity Database

    Miriyala, Vijay Madhav; Řezáč, Jan

    2017-01-01

    Roč. 38, č. 10 (2017), s. 688-697 ISSN 0192-8651 R&D Projects: GA ČR(CZ) GJ16-11321Y Institutional support: RVO:61388963 Keywords : density functional tight binding * DFTB3 * non- covalent interactions * dispersion correction * hydrogen bonding correction Subject RIV: CF - Physical ; Theoretical Chemistry OBOR OECD: Physical chemistry Impact factor: 3.229, year: 2016

  14. Wegner-type Bounds for a Two-particle Lattice Model with a Generic 'Rough' Quasi-periodic Potential

    International Nuclear Information System (INIS)

    Gaume, Martin

    2010-01-01

    In this paper, we consider a class of two-particle tight-binding Hamiltonians, describing pairs of interacting quantum particles on the lattice Z d , d ≥ 1, subject to a common external potential V(x) which we assume quasi-periodic and depending on auxiliary parameters. Such parametric families of ergodic deterministic potentials ('grands ensembles') have been introduced earlier in Chulaevsky (2007), in the framework of single-particle lattice systems, where it was proved that a non-uniform analog of the Wegner bound holds true for a class of quasi-periodic grands ensembles. Using the approach proposed in Chulaevsky and Suhov (Commun Math Phys 283(2):479-489, 2008), we establish volume-dependent Wegner-type bounds for a class of quasi-periodic two-particle lattice systems with a non-random short-range interaction.

  15. Pulse periods and the long-term variations of the X-ray pulsars VELA X-1 and Centaurus X-3

    Science.gov (United States)

    Tsunemi, Hiroshi

    The paper reports recent determinations of the pulse period for two X-ray pulsars, Vela X-1 and Cen X-3, made in 1987 with the All Sky Monitor (ASM) on board the Ginga satellite. The heliocentric pulse periods are 283.09 + or - 0.01 s and 4.8229 + or - 0.0001 s, respectively. These are the longest and shortest values in their respective observational histories. The random walk model for the Vela X-1 pulsar can explain this result as well as those obtained previously. It is also noted that the pulse-period change for the Cen X-3 system shows a 9-yr periodicity. This is probably due to the activity of the companion star rather than to Doppler-shift variations due to a third body or the precession of the neutron star.

  16. Freshness-Preserving Non-Interactive Hierarchical Key Agreement Protocol over WHMS

    Directory of Open Access Journals (Sweden)

    Hyunsung Kim

    2014-12-01

    Full Text Available The digitization of patient health information (PHI for wireless health monitoring systems (WHMSs has brought many benefits and challenges for both patients and physicians. However, security, privacy and robustness have remained important challenges for WHMSs. Since the patient’s PHI is sensitive and the communication channel, i.e., the Internet, is insecure, it is important to protect them against unauthorized entities, i.e., attackers. Otherwise, failure to do so will not only lead to the compromise of a patient’s privacy, but will also put his/her life at risk. This paper proposes a freshness-preserving non-interactive hierarchical key agreement protocol (FNKAP for WHMSs. The FNKAP is based on the concept of the non-interactive identity-based key agreement for communication efficiency. It achieves patient anonymity between a patient and physician, session key secrecy and resistance against various security attacks, especially including replay attacks.

  17. Freshness-Preserving Non-Interactive Hierarchical Key Agreement Protocol over WHMS

    Science.gov (United States)

    Kim, Hyunsung

    2014-01-01

    The digitization of patient health information (PHI) for wireless health monitoring systems (WHMSs) has brought many benefits and challenges for both patients and physicians. However, security, privacy and robustness have remained important challenges for WHMSs. Since the patient's PHI is sensitive and the communication channel, i.e., the Internet, is insecure, it is important to protect them against unauthorized entities, i.e., attackers. Otherwise, failure to do so will not only lead to the compromise of a patient's privacy, but will also put his/her life at risk. This paper proposes a freshness-preserving non-interactive hierarchical key agreement protocol (FNKAP) for WHMSs. The FNKAP is based on the concept of the non-interactive identity-based key agreement for communication efficiency. It achieves patient anonymity between a patient and physician, session key secrecy and resistance against various security attacks, especially including replay attacks. PMID:25513824

  18. Dynamic Behavior Analysis of Non-Contacting Hydrodynamic Finger Seal Based on Fluid-Solid-Interaction Method

    Directory of Open Access Journals (Sweden)

    Su Hua

    2018-01-01

    Full Text Available Finger seal is an advanced compliant seal and can be utilized to separate high (HP and low pressure (LP zones in high speed rotating shaft environment. The work to be presented concerns the dynamic behavior of a repetitive section of a two-layer finger seal with high-and padded low-pressure laminates. The dynamic performance of the finger seal are analyzed by the coupled fluid-solid-interaction (FSI simulations. By using the commercial software ANSYS-CFX, the numerical simulation results of interactions between the gas flow and fingers structural deformation are described when the radial periodic excitation from the shaft applies to the finger seal. And the gas film loading capacity, gas film stiffness and leakage varied with time are put forward in different working conditions. Compared with the dynamic performance analysis results based on equivalent dynamic method, the FSI dynamic analysis shows some different characteristics which are more accordance with actual circumstance. Moreover, it is shown that under low pressure differential and high rotation speed the non-contacting finger seal with advance features both in sealing effectiveness and potential unlimited life span can be obtained by rational structure design. But for the non-contacting finger seal with circumferential convergent pad working in high pressure and low rotating speed conditions, it is difficult to improve the sealing performance by the way of changing the structure parameters of finger seal. It is because the high pressure plays a major role on this sealing situation.

  19. Instrumentation to Monitor Transient Periodic Developing Flow in Non-Newtonian Slurries

    Energy Technology Data Exchange (ETDEWEB)

    Bamberger, Judith A.; Enderlin, Carl W.

    2013-11-15

    Staff at Pacific Northwest National Laboratory have conducted mixing and mobilization experiments with non-Newtonian slurries that exhibit Bingham plastic and shear thinning behavior and shear strength. This paper describes measurement techniques applied to identify the interface between flowing and stationary regions of non-Newtonian slurries that are subjected to transient, periodic, developing flows. Techniques were developed to identify the boundary between the flowing and stationary regions, time to mix, characteristic velocities of the flow field produced by the symmetrically spaced nozzles, and the velocity of the upwell formed in the center of the tank by the intersection of flow from four symmetrically spaced nozzles that impinge upon the tank floor. Descriptions of the instruments and instrument performance are presented. These techniques were an effective approach to characterize mixing phenomena, determine mixing energy required to fully mobilize vessel contents and to determine mixing times for process evaluation.

  20. Super-resolution imaging of a 2.5 kb non-repetitive DNA in situ in the nuclear genome using molecular beacon probes

    Science.gov (United States)

    Ni, Yanxiang; Cao, Bo; Ma, Tszshan; Niu, Gang; Huo, Yingdong; Huang, Jiandong; Chen, Danni; Liu, Yi; Yu, Bin; Zhang, Michael Q; Niu, Hanben

    2017-01-01

    High-resolution visualization of short non-repetitive DNA in situ in the nuclear genome is essential for studying looping interactions and chromatin organization in single cells. Recent advances in fluorescence in situ hybridization (FISH) using Oligopaint probes have enabled super-resolution imaging of genomic domains with a resolution limit of 4.9 kb. To target shorter elements, we developed a simple FISH method that uses molecular beacon (MB) probes to facilitate the probe-target binding, while minimizing non-specific fluorescence. We used three-dimensional stochastic optical reconstruction microscopy (3D-STORM) with optimized imaging conditions to efficiently distinguish sparsely distributed Alexa-647 from background cellular autofluorescence. Utilizing 3D-STORM and only 29–34 individual MB probes, we observed 3D fine-scale nanostructures of 2.5 kb integrated or endogenous unique DNA in situ in human or mouse genome, respectively. We demonstrated our MB-based FISH method was capable of visualizing the so far shortest non-repetitive genomic sequence in 3D at super-resolution. DOI: http://dx.doi.org/10.7554/eLife.21660.001 PMID:28485713

  1. MAXI J1659-152: the shortest orbital period black-hole binary

    DEFF Research Database (Denmark)

    Kuulkers, E.; Kouveliotou, C.; van der Horst, A. J.

    Following the detection of a bright new X-ray source, MAXI J1659-152, a series of observations was triggered with almost all currently flying high-energy missions. We report here on XMM-Newton, INTEGRAL and RXTE observations during the early phase of the X-ray outburst of this transient black-hol...

  2. Measuring modulated luminescence using non-modulated stimulation: Ramping the sample period

    DEFF Research Database (Denmark)

    Poolton, N.R.J.; Bøtter-Jensen, L.; Andersen, C.E.

    2003-01-01

    . Directly analogous results to LM-OSL can, however, be achieved with non-modulated excitation sources, by ramping the sample period (RSP) of luminescence detection. RSP-OSL has the distinct advantage over LM-OSL in that, since the excitation remains at full power, data accumulation times (that can...... be considerable) can be reduced by typically 50%. RSP methods are universally applicable and can be employed, for example, where the excitation source is constant heat, rather than light: here, iso-thermal decay of phosphorescence becomes recorded as a sequence of peaks, corresponding to de-trapping of charge...

  3. Non-covalent interaction between polyubiquitin and GTP cyclohydrolase 1 dictates its degradation.

    Directory of Open Access Journals (Sweden)

    Yu Zhao

    Full Text Available GTP cyclohydrolase 1 (GTPCH1 is the rate-limiting enzyme in the de novo synthesis of tetrahydrobiopterin (BH4. GTPCH1 protein degradation has been reported in animal models of several diseases, including diabetes mellitus and hypertension. However, the molecular mechanisms by which GTPCH1 is degraded remain uncharacterized. Here we report a novel non-covalent interaction between polyubiquitin and GTPCH1 in vitro and in vivo. The non-covalent binding of GTPCH1 to polyubiquitin via an ubiquitin-binding domain (UBD results in ubiquitination and degradation. Ectopic expression of ubiquitin in cultured cells accelerated GTPCH1 degradation. In cultured cells and in vitro assays, Lys48-linked ubiquitin chains, but not Lys63-linked chains, interacted with GTPCH1 and targeted it for degradation. Consistently, proteasome inhibition attenuated GTPCH1 degradation. Finally, direct mutagenesis of an isoleucine (Ile131 in the hydrophobic patch of the GTPCH1 UBD affected its ubiquitin binding and the enzyme stability. Taken together, we conclude that GTPCH1 non-covalently interacts with polyubiquitin via an ubiquitin-binding domain. The polyubiquitin binding directs GTPCH1 ubiquitination and proteasome degradation.

  4. Cosmologic principles of Moche-highland interactions during the Middle Horizon period in Jequetepeque

    OpenAIRE

    Swenson, Edward

    2014-01-01

    In this chapter, I argue that developments characterizing the Late Moche Period in the Jequetepeque Valley, including both the adoption of highland artistic styles at San José de Moro and Huaca Colorada, as well as the proliferation of Moche religious architecture throughout the hinterland, were significantly influenced by interactions with highland societies, including Wari and Cajamarca. I support this thesis by examining the reconfiguration of the chicha-based political economy and the int...

  5. SoundScapes: non-formal learning potentials from interactive VEs

    DEFF Research Database (Denmark)

    Brooks, Tony; Petersson, Eva

    2007-01-01

    Non-formal learning is evident from an inhabited information space that is created from non-invasive multi-dimensional sensor technologies that source human gesture. Libraries of intuitive interfaces empower natural interaction where the gesture is mapped to the multisensory content. Large screen...... and international bodies have consistently recognized SoundScapes which, as a research body of work, is directly responsible for numerous patents. Please note that my full name is Anthony Lewis Brooks. I publish with Anthony Brooks: A. L. Brooks; Tony Brooks.  ...

  6. Productive interactions: heavy particles and non-Gaussianity

    International Nuclear Information System (INIS)

    Flauger, Raphael; Mirbabayi, Mehrdad; Senatore, Leonardo; Silverstein, Eva

    2017-01-01

    We analyze the shape and amplitude of oscillatory features in the primordial power spectrum and non-Gaussianity induced by periodic production of heavy degrees of freedom coupled to the inflaton φ. We find that non-adiabatic production of particles can contribute effects which are detectable or constrainable using cosmological data even if their time-dependent masses are always heavier than the scale φ̇ 1/2 , much larger than the Hubble scale. This provides a new role for UV completion, consistent with the criteria from effective field theory for when heavy fields cannot be integrated out. This analysis is motivated in part by the structure of axion monodromy, and leads to an additional oscillatory signature in a subset of its parameter space. At the level of a quantum field theory model that we analyze in detail, the effect arises consistently with radiative stability for an interesting window of couplings up to of order ∼< 1. The amplitude of the bispectrum and higher-point functions can be larger than that for Resonant Non-Gaussianity, and its signal/noise may be comparable to that of the corresponding oscillations in the power spectrum (and even somewhat larger within a controlled regime of parameters). Its shape is distinct from previously analyzed templates, but was partly motivated by the oscillatory equilateral searches performed recently by the Planck collaboration. We also make some general comments about the challenges involved in making a systematic study of primordial non-Gaussianity.

  7. Productive interactions: heavy particles and non-Gaussianity

    Energy Technology Data Exchange (ETDEWEB)

    Flauger, Raphael [Department of Physics, The University of Texas at Austin, Austin, TX, 78712 (United States); Mirbabayi, Mehrdad [Institute for Advanced Study, Princeton, NJ 08540 (United States); Senatore, Leonardo; Silverstein, Eva, E-mail: flauger@physics.ucsd.edu, E-mail: mehrdadm@ias.edu, E-mail: senatore@stanford.edu, E-mail: evas@slac.stanford.edu [Stanford Institute for Theoretical Physics, Stanford University, Stanford, CA 94305 (United States)

    2017-10-01

    We analyze the shape and amplitude of oscillatory features in the primordial power spectrum and non-Gaussianity induced by periodic production of heavy degrees of freedom coupled to the inflaton φ. We find that non-adiabatic production of particles can contribute effects which are detectable or constrainable using cosmological data even if their time-dependent masses are always heavier than the scale φ̇{sup 1/2}, much larger than the Hubble scale. This provides a new role for UV completion, consistent with the criteria from effective field theory for when heavy fields cannot be integrated out. This analysis is motivated in part by the structure of axion monodromy, and leads to an additional oscillatory signature in a subset of its parameter space. At the level of a quantum field theory model that we analyze in detail, the effect arises consistently with radiative stability for an interesting window of couplings up to of order ∼< 1. The amplitude of the bispectrum and higher-point functions can be larger than that for Resonant Non-Gaussianity, and its signal/noise may be comparable to that of the corresponding oscillations in the power spectrum (and even somewhat larger within a controlled regime of parameters). Its shape is distinct from previously analyzed templates, but was partly motivated by the oscillatory equilateral searches performed recently by the Planck collaboration. We also make some general comments about the challenges involved in making a systematic study of primordial non-Gaussianity.

  8. Non-linear interactions of multi-level atoms with a near-resonant standing wave

    International Nuclear Information System (INIS)

    O'Kane, T.J.; Scholten, R.E.; Walkiewicz, M.R.; Farrell, P.M.

    1998-01-01

    Using a semiclassical density matrix formalism we have calculated the behavior of multi-level atoms interacting with a standing wave field, and show how complex non-linear phenomena, including multi-photon effects, combine to produce saturation spectra as observed in experiments. We consider both 20-level sodium and 24-level rubidium models, contrasting these with a simple 2-level case. The influence of parameters such as atomic trajectory and the time the atom remains in the beam are shown to have a critical effect on the lineshape of these resonances and the emission/absorption processes. Stable oscillations in the excited state populations for both the two-level and multi-level cases are shown to be limit cycles. These limit cycles undergo period doubling as the system evolves into chaos. Finally, using a Monte Carlo treatment, these processes average to produce saturated absorption spectra complete with power and Doppler broadening effects consistent with experiment. (authors)

  9. A Review of Verbal and Non-Verbal Human-Robot Interactive Communication

    OpenAIRE

    Mavridis, Nikolaos

    2014-01-01

    In this paper, an overview of human-robot interactive communication is presented, covering verbal as well as non-verbal aspects of human-robot interaction. Following a historical introduction, and motivation towards fluid human-robot communication, ten desiderata are proposed, which provide an organizational axis both of recent as well as of future research on human-robot communication. Then, the ten desiderata are examined in detail, culminating to a unifying discussion, and a forward-lookin...

  10. Optical Frequency Mixing in Periodically-Patterned and in Quasi-Periodically-Patterned Nonlinear media

    International Nuclear Information System (INIS)

    Arie, A.

    1999-01-01

    Nonlinear frequency mixing processes, e.g. second harmonic generation, sum and difference frequency generation, etc., require matching of the phases of the interacting waves. The traditional method to achieve it is by selecting a specific angle of propagation in a birefringent nonlinear crystal. The main limitation of the birefringent phase matching method stems from the fact that for many interesting interactions, the phase matching condition cannot be satisfied in a specific crystal. This obstacle can be removed by the technique of quasi-phase-matching (QPM), where the nonlinear coefficient of the material is modulated at a fixed spatial frequency that equals the wave-vector phase mismatch between the interacting waves. An important development in recent years is the ability to periodically reverse the sign of the nonlinear coefficient in ferroelectric crystals by applying a high electric field through a periodic electrode. Some recent QPM interactions in periodically-poled KTP that were recently achieved at Tel-Aviv University include continuous-wave optical parametric oscillations, as well as generation of tunable mid-infrared radiation by difference frequency generation. Periodic patterning of the nonlinear coefficient enables to phase match only a single interaction. It would be advantageous to further extend the applications of this technique in order to simultaneously satisfy several interactions on a single crystal. This cannot be usually achieved in a periodic pattern, however more sophisticated quasi-periodic structures can be designed in this case. An interesting analogy can be drawn between artificially-made quasi-periodically-patterned nonlinear crystals and quasi-crystals found in nature, in rapidly-cooled metallic alloys

  11. Logic of non-interacting programs and reactive systems

    OpenAIRE

    Shelekhov, Vladimir; Tumurov, Erdem

    2012-01-01

    The notion of a program logic is introduced to denote a set of predicates which are true in different program points. The program logic can be easily constructed for different kinds of statements of an imperative or a functional language with data types except pointers. For a non-interacting program, a total correctness formula based on the program logic is defined. The rules of program correctness proof have been developed for proving the statements of various kinds. For a reactive system, t...

  12. Effect of interaction with clowns on vital signs and non-verbal communication of hospitalized children.

    Science.gov (United States)

    Alcântara, Pauline Lima; Wogel, Ariane Zonho; Rossi, Maria Isabela Lobo; Neves, Isabela Rodrigues; Sabates, Ana Llonch; Puggina, Ana Cláudia

    2016-12-01

    Compare the non-verbal communication of children before and during interaction with clowns and compare their vital signs before and after this interaction. Uncontrolled, intervention, cross-sectional, quantitative study with children admitted to a public university hospital. The intervention was performed by medical students dressed as clowns and included magic tricks, juggling, singing with the children, making soap bubbles and comedic performances. The intervention time was 20minutes. Vital signs were assessed in two measurements with an interval of one minute immediately before and after the interaction. Non-verbal communication was observed before and during the interaction using the Non-Verbal Communication Template Chart, a tool in which nonverbal behaviors are assessed as effective or ineffective in the interactions. The sample consisted of 41 children with a mean age of 7.6±2.7 years; most were aged 7 to 11 years (n=23; 56%) and were males (n=26; 63.4%). There was a statistically significant difference in systolic and diastolic blood pressure, pain and non-verbal behavior of children with the intervention. Systolic and diastolic blood pressure increased and pain scales showed decreased scores. The playful interaction with clowns can be a therapeutic resource to minimize the effects of the stressing environment during the intervention, improve the children's emotional state and reduce the perception of pain. Copyright © 2016 Sociedade de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved.

  13. The dark sector from interacting canonical and non-canonical scalar fields

    International Nuclear Information System (INIS)

    De Souza, Rudinei C; Kremer, Gilberto M

    2010-01-01

    In this work general models with interactions between two canonical scalar fields and between one non-canonical (tachyon type) and one canonical scalar field are investigated. The potentials and couplings to the gravity are selected through the Noether symmetry approach. These general models are employed to describe interactions between dark energy and dark matter, with the fields being constrained by the astronomical data. The cosmological solutions of some cases are compared with the observed evolution of the late Universe.

  14. Aharonov-Bohm oscillations with fractional period in a multichannel Wigner crystal ring

    International Nuclear Information System (INIS)

    Krive, I.V.; Krokhin, A.A.

    1997-01-01

    We study the persistent current in a quasi 1D ring with strongly correlated electrons forming a multichannel Wigner crystal (WC). The influence of the Coulomb interaction manifests itself only in the presence of external scatterers that pin the WC. Two regimes of weak and strong pinning are considered. For strong pinning we predict the Aharonov-Bohm oscillations with fractional period. Fractionalization is due to the interchannel coupling in the process of quantum tunneling of the WC. The fractional period depends on the filling of the channels and may serve as an indicator of non-Fermi-liquid behaviour of interacting electrons in quasi 1D rings. (author). 20 refs

  15. Non-linear effective Lagrangian treatment of 'Penguin' interaction

    International Nuclear Information System (INIS)

    Pham, T.N.

    1984-01-01

    Using the non-linear effective lagrangian technique, we show explicitly that only derivative coupling is allowed for the K - π, K -> 2 π and K -> 3 π transitions induced by the ΔS = 1 Penguin operator of SVZ in agreement with chiral symmetry requirements. From a derivative coupling (3, anti 3) mass term and the SU(3) breaking effect for fsub(K)/fsub(π), we estimate the strength of the Penguin interactions and find it too small to account for the ΔI = 1/2 amplitude. (orig.)

  16. Dynamic hubs show competitive and static hubs non-competitive regulation of their interaction partners.

    Directory of Open Access Journals (Sweden)

    Apurv Goel

    Full Text Available Date hub proteins have 1 or 2 interaction interfaces but many interaction partners. This raises the question of whether all partner proteins compete for the interaction interface of the hub or if the cell carefully regulates aspects of this process? Here, we have used real-time rendering of protein interaction networks to analyse the interactions of all the 1 or 2 interface hubs of Saccharomyces cerevisiae during the cell cycle. By integrating previously determined structural and gene expression data, and visually hiding the nodes (proteins and their edges (interactions during their troughs of expression, we predict when interactions of hubs and their partners are likely to exist. This revealed that 20 out of all 36 one- or two- interface hubs in the yeast interactome fell within two main groups. The first was dynamic hubs with static partners, which can be considered as 'competitive hubs'. Their interaction partners will compete for the interaction interface of the hub and the success of any interaction will be dictated by the kinetics of interaction (abundance and affinity and subcellular localisation. The second was static hubs with dynamic partners, which we term 'non-competitive hubs'. Regulatory mechanisms are finely tuned to lessen the presence and/or effects of competition between the interaction partners of the hub. It is possible that these regulatory processes may also be used by the cell for the regulation of other, non-cell cycle processes.

  17. WIYN Open Cluster Study: Binary Orbits and Tidal Circularization in NGC 6819

    Science.gov (United States)

    Morscher, Meagan B.; Mathieu, R. D.; Kaeppler, S.; Hole, K. T.; Meibom, S.

    2006-12-01

    We are conducting a comprehensive stellar radial-velocity survey in NGC 6819, a rich, intermediate age ( 2.4 Gyr) open cluster with [Fe/H] -0.05. As of October 2006, we have obtained 7065 radial-velocity measurements of 1409 stars using the WIYN Hydra Multi-Object Spectrograph, with typical velocity measurement precisions of 0.4 km/s. Using an E/I criterion of 3, we have identified 282 velocity variables. In the past year we have expanded the number of final orbital solutions by 45 to a total of more than 80 solutions. In coeval stellar populations, circular binaries tend to have the shortest orbital periods, while longer period binaries show a distribution of non-zero eccentricities. The circularization of the shortest period orbits is the result of an exchange of stellar and orbital angular momentum due to tidal interactions. We defined a population’s tidal circularization period as the longest orbital period at which a binary of typical initial eccentricity has become circularized (e.g., has evolved to an eccentricity e = 0.01) over the lifetime of the cluster (Meibom & Mathieu, 2005, ApJ, 620, 970). We are studying the trend of increasing tidal circularization periods with population age. Preliminary results in NGC 6819 indicate a tidal circularization period of 7.5 days, which is consistent with this overall trend. We will recalculate the tidal circularization period in order to include the latest sample of orbital solutions. This comprehensive survey also allows us to investigate the relative spatial distributions of spectroscopic binaries and other constant-velocity cluster members of similar mass. We find the spectroscopic binaries to be more centrally concentrated at a statistically significant level, which we attribute to energy equipartition processes. MM was supported by REU NSF grant AST-0453442. RDM, SK, KTH, and SM were supported by NSF grant AST-0406615.

  18. Revisiting the density scaling of the non-interacting kinetic energy.

    Science.gov (United States)

    Borgoo, Alex; Teale, Andrew M; Tozer, David J

    2014-07-28

    Scaling relations play an important role in the understanding and development of approximate functionals in density functional theory. Recently, a number of these relationships have been redefined in terms of the Kohn-Sham orbitals [Calderín, Phys. Rev. A: At., Mol., Opt. Phys., 2013, 86, 032510]. For density scaling the author proposed a procedure involving a multiplicative scaling of the Kohn-Sham orbitals whilst keeping their occupation numbers fixed. In the present work, the differences between this scaling with fixed occupation numbers and that of previous studies, where the particle number change implied by the scaling was accommodated through the use of the grand canonical ensemble, are examined. We introduce the terms orbital and ensemble density scaling for these approaches, respectively. The natural ambiguity of the density scaling of the non-interacting kinetic energy functional is examined and the ancillary definitions implicit in each approach are highlighted and compared. As a consequence of these differences, Calderín recovered a homogeneity of degree 1 for the non-interacting kinetic energy functional under orbital scaling, contrasting recent work by the present authors [J. Chem. Phys., 2012, 136, 034101] where the functional was found to be inhomogeneous under ensemble density scaling. Furthermore, we show that the orbital scaling result follows directly from the linearity and the single-particle nature of the kinetic energy operator. The inhomogeneity of the non-interacting kinetic energy functional under ensemble density scaling can be quantified by defining an effective homogeneity. This quantity is shown to recover the homogeneity values for important approximate forms that are exact for limiting cases such as the uniform electron gas and one-electron systems. We argue that the ensemble density scaling provides more insight into the development of new functional forms.

  19. Non-Newtonian fluid structure interaction in flexible biomimetic microchannels

    Science.gov (United States)

    Kiran, M.; Dasgupta, Sunando; Chakraborty, Suman

    2017-11-01

    To investigate the complex fluid structure interactions in a physiologically relevant microchannel with deformable wall and non-Newtonian fluid that flows within it, we fabricated cylindrical microchannels of various softness out of PDMS. Experiments to measure the transient pressure drop across the channel were carried out with high sampling frequencies to capture the intricate flow physics. In particular, we showed that the waveforms varies greatly for each of the non-Newtonian and Newtonian cases for both non-deformable and deformable microchannels in terms of the peak amplitude, r.m.s amplitude and the crest factor. In addition, we carried out frequency sweep experiments to evaluate the frequency response of the system. We believe that these results will aid in the design of polymer based microfluidic phantoms for arterial FSI studies, and in particular for studying blood analog fluids in cylindrical microchannels as well as developing frequency specific Lab-on-chip systems for medical diagnostics.

  20. Improved harmonic balance approach to periodic solutions of non-linear jerk equations

    International Nuclear Information System (INIS)

    Wu, B.S.; Lim, C.W.; Sun, W.P.

    2006-01-01

    An analytical approximate approach for determining periodic solutions of non-linear jerk equations involving third-order time-derivative is presented. This approach incorporates salient features of both Newton's method and the method of harmonic balance. By appropriately imposing the method of harmonic balance to the linearized equation, the approach requires only one or two iterations to predict very accurate analytical approximate solutions for a large range of initial velocity amplitude. One typical example is used to verify and illustrate the usefulness and effectiveness of the proposed approach

  1. Search for primarily non-interacting decay modes of the upsilon

    International Nuclear Information System (INIS)

    Leffler, J.S.

    1986-03-01

    The hadronic transition UPSILON(2S) → π 0 π 0 UPSILON(1S) is utilized to search for the reactions: UPSILON(1S) → non-interacting particles and UPSILON(1S) → γ + non-interacting particles. 44 pb -1 of UPSILON(2S) data were taken by the Crystal Ball detector at the DORIS II storage ring in order to perform this study. An upper limit of BR(UPSILON → Unseen) -1 of UPSILON(2S) data was available for this study. An upper limit on the branching ratio BR(UPSILON → γ + Unseen) is measured for photon energies in the range 500 MeV -3 (90% C.L.), is obtained. The compact size of the Crystal Ball detector enhances the observable branching ratio for noninteracting particles with short lifetimes such as massive axions. The identification of the recent Darmstadt events with a 1.6 MeV axion is excluded by the present result assuming the minimal Peccei-Quinn model. Limits on the spontaneous supersymmetry breaking mass scale are also derived as a function of gravitino mass

  2. New effects of non-standard self-interactions of neutrinos in a supernova

    Energy Technology Data Exchange (ETDEWEB)

    Das, Anirban; Dighe, Amol; Sen, Manibrata, E-mail: anirbandas@theory.tifr.res.in, E-mail: amol@theory.tifr.res.in, E-mail: manibrata@theory.tifr.res.in [Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai, 400005 (India)

    2017-05-01

    Neutrino self-interactions are known to lead to non-linear collective flavor oscillations in a core-collapse supernova. We point out new possible effects of non-standard self-interactions (NSSI) of neutrinos on flavor conversions in a two-flavor framework. We show that, for a single-energy neutrino-antineutrino ensemble, a flavor instability is generated even in normal hierarchy for large enough NSSI. Using a toy model for the neutrino spectra, we show that flavor-preserving NSSI lead to pinching of spectral swaps, while flavor-violating NSSI cause swaps to develop away from a spectral crossing or even in the absence of a spectral crossing. Consequently, NSSI could give rise to collective oscillations and spectral splits even during neutronization burst, for both hierarchies.

  3. k-Shortest routing of trains on shunting yards

    NARCIS (Netherlands)

    Riezebos, Jan; van Wezel, Wout

    2009-01-01

    We consider the problem of designing algorithmic support for k-best routing decisions in train shunting scheduling. A study at the Netherlands Railways revealed that planners like to interact with the solution process of finding suitable routes. Two types of interaction were required: the

  4. More than a meal: integrating non-feeding interactions into food webs

    Science.gov (United States)

    Kéfi, Sonia; Berlow, Eric L.; Wieters, Evie A.; Navarrete, Sergio A.; Petchey, Owen L.; Wood, Spencer A.; Boit, Alice; Joppa, Lucas N.; Lafferty, Kevin D.; Williams, Richard J.; Martinez, Neo D.; Menge, Bruce A.; Blanchette, Carol A.; Iles, Alison C.; Brose, Ulrich

    2012-01-01

    Organisms eating each other are only one of many types of well documented and important interactions among species. Other such types include habitat modification, predator interference and facilitation. However, ecological network research has been typically limited to either pure food webs or to networks of only a few (conceptual framework that organises this diversity into three main functional classes defined by how they modify specific parameters in a dynamic food web model. This approach provides a path forward for incorporating non-trophic interactions in traditional food web models and offers a new perspective on tackling ecological complexity that should stimulate both theoretical and empirical approaches to understanding the patterns and dynamics of diverse species interactions in nature.

  5. Non - minimal interaction of gravity with other physical fields: an overview

    International Nuclear Information System (INIS)

    Novello, M.; Oliveira, L.A.R. de.

    1986-01-01

    A review on some modern developments concerning the interaction of gravity with other physical fields. It is argued that a suitable context for an account of their dynamical interplay is that of the non-minimal (e.g., conformal) coupling of these fields to gravity. Some interesting features of non-minimal coupling, such as the connection with Weyl-integrable spacetime (WIST) structure, the generation of eternal Universes, the appearance of a cosmological constant and the possible induction of repulsive gravity via spontaneous symmetry breaking (SSB) mechanisms, are discussed. In particular, examines a simple case of strong interacting scalar particles (such as the well-Known elastic reaction ΠK → ΠK), in a curved background, thereby obtaining the curious result that the actual, observed value of the strong coupling constant and the minimum value allowable, in order to preclude antigravity, are related by Eddington's number 10 39 . (Author) [pt

  6. Non-nominal interaction of gravity with other physical fields: An overiview

    International Nuclear Information System (INIS)

    Novello, M.; Oliveira, L.A.R. de

    1987-01-01

    A review is presented of some modern developments concerning the interaction of gravity with other physical fields. It is argued that a suitable context for an account of their dynamical interplay is that of the non-minimal (e.g. conformal) coupling of these fields to gravity. Some interesting features of non-minimal coupling, such as the connection with Weyl-integrable spacetime (WIST) structure, the generation of eternal Universes, the appearance of a cosmological constant and the possible induction of repulsive gravity via spontaneous breaking (SSB) mechanisms, are discussed. In particular, a simple case of strong-interacting scalar particles is examined (such as the well-Known elastic reaction ΠK -> ΠK), in a curved background, thereby obtaining the curious resul that the actual, observed value of the strong coupling constant and the minimum allowable value, in order to preclude antigravity, are related by Eddington's number 10 39 . (author) [pt

  7. How should periods without social interaction be scheduled? Children's preference for practical schedules of positive reinforcement.

    Science.gov (United States)

    Luczynski, Kevin C; Hanley, Gregory P

    2014-01-01

    Several studies have shown that children prefer contingent reinforcement (CR) rather than yoked noncontingent reinforcement (NCR) when continuous reinforcement is programmed in the CR schedule. Preference has not, however, been evaluated for practical schedules that involve CR. In Study 1, we assessed 5 children's preference for obtaining social interaction via a multiple schedule (periods of fixed-ratio 1 reinforcement alternating with periods of extinction), a briefly signaled delayed reinforcement schedule, and an NCR schedule. The multiple schedule promoted the most efficient level of responding. In general, children chose to experience the multiple schedule and avoided the delay and NCR schedules, indicating that they preferred multiple schedules as the means to arrange practical schedules of social interaction. In Study 2, we evaluated potential controlling variables that influenced 1 child's preference for the multiple schedule and found that the strong positive contingency was the primary variable. © Society for the Experimental Analysis of Behavior.

  8. Integration and visualization of non-coding RNA and protein interaction networks

    DEFF Research Database (Denmark)

    Junge, Alexander; Refsgaard, Jan Christian; Garde, Christian

    Non-coding RNAs (ncRNAs) fulfill a diverse set of biological functions relying on interactions with other molecular entities. The advent of new experimental and computational approaches makes it possible to study ncRNAs and their associations on an unprecedented scale. We present RAIN (RNA Associ......) co-occurrences found by text mining Medline abstracts. Each resource was assigned a reliability score by assessing its agreement with a gold standard set of microRNA-target interactions. RAIN is available at: http://rth.dk/resources/rain...

  9. Soil-Structure Interaction for Non-Slender, Large-Diameter Offshore Monopiles

    DEFF Research Database (Denmark)

    Sørensen, Søren Peder Hyldal

    conducted. The initial part of p-y curves for non-slender piles has been investigated by means of numerical modelling. The general behaviour of eccentrically loaded non-slender piles has been investigated by physical modelling. These tests have been conducted in the pressure tank at Aalborg University....... The monopile foundation concept has been employed as the foundation for the majority of the currently installed offshore wind turbines. Therefore, this PhD thesis concerns the soil-pile interaction for non-slender, large-diameter offshore piles. A combination of numerical and physical modelling has been....... Hence, the application of an overburden pressure is possible. The timescale of the backfill process and the compaction of soil material backfilled around piles in storm conditions have been investigated by means of large-scale physical modelling....

  10. Testing periodically integrated autoregressive models

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); M.J. McAleer (Michael)

    1997-01-01

    textabstractPeriodically integrated time series require a periodic differencing filter to remove the stochastic trend. A non-periodic integrated time series needs the first-difference filter for similar reasons. When the changing seasonal fluctuations for the non-periodic integrated series can be

  11. The Simulation and Experiment of a Non-Cross-Feeding Printed Log-Periodic Antenna

    Directory of Open Access Journals (Sweden)

    Chun-Ying Kang

    2015-01-01

    Full Text Available A non-cross-fed printed log-periodic antenna is simulated and studied experimentally. To avoid complex feeding with long coaxial line, the non-cross-feeding structure is applied in this antenna. The software CST Microwave Studio is employed to simulate the proposed antenna, and the optimized antenna model is obtained. According to the simulation results, the antenna prototype is produced and measured. Simulation and measured results show that the antenna is with S11<-10 dB in band of 4.2–9.2 GHz. And the radiation pattern and gain vary steadily in this band, which achieves requirements for wideband antenna. This antenna design can be extended to the design of the antenna integrated in communication circuit.

  12. Globular and disordered – the non-identical twins in protein-protein interactions

    Directory of Open Access Journals (Sweden)

    Kaare eTeilum

    2015-07-01

    Full Text Available In biology proteins from different structural classes interact across and within classes in ways that are optimized to achieve balanced functional outputs. The interactions between intrinsically disordered proteins (IDPs and other proteins rely on changes in flexibility and this is seen as a strong determinant for their function. This has fostered the notion that IDP’s bind with low affinity but high specificity. Here we have analyzed available detailed thermodynamic data for protein-protein interactions to put to the test if the thermodynamic profiles of IDP interactions differ from those of other protein-protein interactions. We find that ordered proteins and the disordered ones act as non identical twins operating by similar principles but where the disordered proteins complexes are on average less stable by 2.5 kcal mol-1.

  13. Between and beyond additivity and non-additivity : the statistical modelling of genotype by environment interaction in plant breeding

    OpenAIRE

    Eeuwijk, van, F.A.

    1996-01-01

    In plant breeding it is a common observation to see genotypes react differently to environmental changes. This phenomenon is called genotype by environment interaction. Many statistical approaches for analysing genotype by environment interaction rely heavily on the analysis of variance model. Genotype by environment interaction is then taken to be equivalent to non-additivity. This thesis criticizes the analysis of variance approach. Modelling genotype by environment interaction by non-addit...

  14. Numerical Investigation of Compressor Non-Synchronous Vibration with Full Annulus Rotor-Stator Interaction

    Science.gov (United States)

    Espinal, Daniel

    The objective of this research is to investigate and confirm the periodicity of the Non-Synchronous Vibration (NSV) mechanism of a GE axial compressor with a full-annulus simulation. A second objective is to develop a high fidelity single-passage tool with time-accurate unsteady capabilities able to capture rotor-stator interactions and NSV excitation response. A high fidelity methodology for axial turbomachinery simulation is developed using the low diffusion shock-capturing Riemann solver with high order schemes, the Spalart-Allmaras turbulence closure model, the fully conservative unsteady sliding BC for rotor-stator interaction with extension to full-annulus and single-passage configurations, and the phase lag boundary conditions applied to rotor-stator interface and circumferential BC. A URANS solver is used and captures the NSV flow excitation frequency of 2439 Hz, which agrees reasonably well with the measured NSV frequency of 2600 Hz from strain gage test data. It is observed that the circumferentially traveling vortex formed in the vicinity of the rotor tip propagates at the speed of a non-engine order frequency and causes the NSV. The vortex travels along the suction surface of the blade and crosses the passage outlet near blade trailing edge. Such a vortex motion trajectory repeats in each blade passage and generates two low pressure regions due to the vortex core positions, one at the leading edge and one at the trailing edge, both are oscillating due to the vortex coming and leaving. These two low pressure regions create a pair of coupling forces that generates a torsion moment causing NSV. The full-annulus simulation shows that the circumferentially traveling vortex has fairly periodical behavior and is a full annulus structure. Also, frequencies below the NSV excitation frequency of 2439 Hz with large amplitudes in response to flow-separation related phenomena are present. This behavior is consistent with experimental measurements. For

  15. Non-Hermitian interaction representation and its use in relativistic quantum mechanics

    Czech Academy of Sciences Publication Activity Database

    Znojil, Miloslav

    2017-01-01

    Roč. 385, č. 10 (2017), s. 162-179 ISSN 0003-4916 R&D Projects: GA ČR GA16-22945S Institutional support: RVO:61389005 Keywords : unitary quantum systems * non-Hermitian version of Dirac's interaction picture * complete set of time-evolution equations * application in relativistic quantum mechanics * Klein-Gordon example with space-time-dependent mass Subject RIV: BE - Theoretical Physics OBOR OECD: Atomic, molecular and chemical physics ( physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect) Impact factor: 2.465, year: 2016

  16. Interactive affective sharing versus non-interactive affective sharing in work groups : Comparative effects of group affect on work group performance and dynamics

    NARCIS (Netherlands)

    Klep, Annefloor; Wisse, Barbara; Van Der Flier, Henk

    This study explores whether the dynamic path to group affect, which is characterized by interactive affective sharing processes, yields different effects on task performance and group dynamics than the static path to group affect, which arises from non-interactive affective sharing. The results of

  17. Interactive affective sharing versus non-interactive affective sharing in work groups: Comparative effects of group affect on work group performance and dynamics

    NARCIS (Netherlands)

    Klep, A.H.M.; Wisse, B.M.; van der Flier, H.

    2011-01-01

    This study explores whether the dynamic path to group affect, which is characterized by interactive affective sharing processes, yields different effects on task performance and group dynamics than the static path to group affect, which arises from non-interactive affective sharing. The results of

  18. Quantum return probability of a system of N non-interacting lattice fermions

    Science.gov (United States)

    Krapivsky, P. L.; Luck, J. M.; Mallick, K.

    2018-02-01

    We consider N non-interacting fermions performing continuous-time quantum walks on a one-dimensional lattice. The system is launched from a most compact configuration where the fermions occupy neighboring sites. We calculate exactly the quantum return probability (sometimes referred to as the Loschmidt echo) of observing the very same compact state at a later time t. Remarkably, this probability depends on the parity of the fermion number—it decays as a power of time for even N, while for odd N it exhibits periodic oscillations modulated by a decaying power law. The exponent also slightly depends on the parity of N, and is roughly twice smaller than what it would be in the continuum limit. We also consider the same problem, and obtain similar results, in the presence of an impenetrable wall at the origin constraining the particles to remain on the positive half-line. We derive closed-form expressions for the amplitudes of the power-law decay of the return probability in all cases. The key point in the derivation is the use of Mehta integrals, which are limiting cases of the Selberg integral.

  19. Neostigmine interactions with non steroidal anti-inflammatory drugs.

    Science.gov (United States)

    Miranda, Hugo F; Sierralta, Fernando; Pinardi, Gianni

    2002-04-01

    1. The common mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs) is the inhibition of the enzyme cyclo-oxygenase (COX), however, this inhibition is not enough to completely account for the efficacy of these agents in several models of acute pain. 2. It has been demonstrated that cholinergic agents can induce antinociception, but the nature of the interaction between these agents and NSAIDs drugs has not been studied. The present work evaluates, by isobolographic analysis, the interactions between the cholinergic indirect agonist neostigmine (NEO) and NSAIDs drugs, using a chemical algesiometric test. 3. Intraperitoneal (i.p.) or intrathecal (i.t.) administration of NEO and of the different NSAIDs produced dose-dependent antinociception in the acetic acid writhing test of the mouse. 4. The i.p. or i.t. co-administration of fixed ratios of ED(50) fractions of NSAIDs and NEO, resulted to be synergistic or supra-additive for the combinations ketoprofen (KETO) and NEO, paracetamol (PARA) and NEO) and diclofenac (DICLO) and NEO administered i.p. However, the same combinations administered i.t. were only additive. In addition, the combinations meloxicam (MELO) and NEO and piroxicam (PIRO) and NEO, administered either i.p. or i.t., were additive. 5. The results suggest that the co-administration of NEO with some NSAIDs (e.g. KETO, PARA or DICLO) resulted in a synergistic interaction, which may provide evidence of supraspinal antinociception modulation by the increased acetylcholine concentration in the synaptic cleft of cholinergic interneurons. The interaction obtained between neostigmine and the NSAIDs could carry important clinical implications.

  20. Non-conventional screening of the Coulomb interaction in low-dimensional and finite-size systems

    NARCIS (Netherlands)

    van den Brink, J.; Sawatzky, G.A.

    2000-01-01

    We study the screening of the Coulomb interaction in non-polar systems by polarizable atoms. We show that in low dimensions and small finite-size systems this screening deviates strongly from that conventionally assumed. In fact in one dimension the short-range interaction is strongly screened and

  1. A new 3D immersed boundary method for non-Newtonian fluid-structure-interaction with application

    Science.gov (United States)

    Zhu, Luoding

    2017-11-01

    Motivated by fluid-structure-interaction (FSI) phenomena in life sciences (e.g., motions of sperm and cytoskeleton in complex fluids), we introduce a new immersed boundary method for FSI problems involving non-Newtonian fluids in three dimensions. The non-Newtonian fluids are modelled by the FENE-P model (including the Oldroyd-B model as an especial case) and numerically solved by a lattice Boltzmann scheme (the D3Q7 model). The fluid flow is modelled by the lattice Boltzmann equations and numerically solved by the D3Q19 model. The deformable structure and the fluid-structure-interaction are handled by the immersed boundary method. As an application, we study a FSI toy problem - interaction of an elastic plate (flapped at its leading edge and restricted nowhere else) with a non-Newtonian fluid in a 3D flow. Thanks to the support of NSF-DMS support under research Grant 1522554.

  2. Referential Interactions of Turkish-Learning Children with Their Caregivers about Non-Absent Objects: Integration of Non-Verbal Devices and Prior Discourse

    Science.gov (United States)

    Ates, Beyza S.; Küntay, Aylin C.

    2018-01-01

    This paper examines the way children younger than two use non-verbal devices (i.e., deictic gestures and communicative functional acts) and pay attention to discourse status (i.e., prior mention vs. newness) of referents in interactions with caregivers. Data based on semi-naturalistic interactions with caregivers of four children, at ages 1;00,…

  3. Non-standard interaction effects at reactor neutrino experiments

    International Nuclear Information System (INIS)

    Ohlsson, Tommy; Zhang, He

    2009-01-01

    We study non-standard interactions (NSIs) at reactor neutrino experiments, and in particular, the mimicking effects on θ 13 . We present generic formulas for oscillation probabilities including NSIs from sources and detectors. Instructive mappings between the fundamental leptonic mixing parameters and the effective leptonic mixing parameters are established. In addition, NSI corrections to the mixing angles θ 13 and θ 12 are discussed in detailed. Finally, we show that, even for a vanishing θ 13 , an oscillation phenomenon may still be observed in future short baseline reactor neutrino experiments, such as Double Chooz and Daya Bay, due to the existences of NSIs

  4. Non-thyroid cancer in Northern Ukraine in the post-Chernobyl period: Short report.

    Science.gov (United States)

    Hatch, M; Ostroumova, E; Brenner, A; Federenko, Z; Gorokh, Y; Zvinchuk, O; Shpak, V; Tereschenko, V; Tronko, M; Mabuchi, K

    2015-06-01

    The Chernobyl nuclear power plant accident in Ukraine in 1986 led to widespread radioactive releases into the environment - primarily of radioiodines and cesium - heavily affecting the northern portions of the country, with settlement-averaged thyroid doses estimated to range from 10 mGy to more than 10 Gy. The increased risk of thyroid cancer among exposed children and adolescents is well established but the impact of radioactive contamination on the risk of other types of cancer is much less certain. To provide data on a public health issue of major importance, we have analyzed the incidence of non-thyroid cancers during the post-Chernobyl period in a well-defined cohort of 13,203 individuals who were <18 years of age at the time of the accident. The report is based on standardized incidence ratio (SIR) analysis of 43 non-thyroid cancers identified through linkage with the National Cancer Registry of Ukraine for the period 1998 through 2009. We compared the observed and expected number of cases in three cancer groupings: all solid cancers excluding thyroid, leukemia, and lymphoma. Our analyses found no evidence of a statistically significant elevation in cancer risks in this cohort exposed at radiosensitive ages, although the cancer trends, particularly for leukemia (SIR=1.92, 95% confidence interval: 0.69; 4.13), should continue to be monitored. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Influence of magnetic dipole and magnetoelastic interactions on the phase states of 2D non-Heisenberg ferromagnetic with complex exchange interactions

    International Nuclear Information System (INIS)

    Fridman, Yu.A.; Matunin, D.A.; Klevets, Ph.N.; Kosmachev, O.A.

    2009-01-01

    The phase states of the 2D non-Heisenberg ferromagnetic with anisotropic bilinear and biquadratic exchange interactions are investigated. The limiting cases of the system under consideration are the two-dimensional XY-model with biquadratic exchange interaction and the isotropic Heisenberg ferromagnetic. The account of the magnetic dipole interaction leads to the realization of spatially inhomogeneous quadrupolar phase. The stability regions of various phase transitions for different values of the material parameters are studied. The phase diagram is built. Besides, the temperature phase transitions are investigated. The influence of the magnetoelastic interaction on the formation of the long-range quadrupolar order is determined.

  6. Comparative analysis between endometrial proteomes of pregnant and non-pregnant ewes during the peri-implantation period.

    Science.gov (United States)

    Zhao, Haichao; Sui, Linlin; Miao, Kai; An, Lei; Wang, Dong; Hou, Zhuocheng; Wang, Rui; Guo, Min; Wang, Zhilong; Xu, Jiqiang; Wu, Zhonghong; Tian, Jianhui

    2015-01-01

    Early pregnancy failure has a profound impact on both human reproductive health and animal production. 2/3 pregnancy failures occur during the peri-implantation period; however, the underlying mechanism(s) remains unclear. Well-organized modification of the endometrium to a receptive state is critical to establish pregnancy. Aberrant endometrial modification during implantation is thought to be largely responsible for early pregnancy loss. In this study, using well-managed recipient ewes that received embryo transfer as model, we compared the endometrial proteome between pregnant and non-pregnant ewes during implantation period. After embryo transfer, recipients were assigned as pregnant or non-pregnant ewes according to the presence or absence of an elongated conceptus at Day 17 of pregnancy. By comparing the endometrial proteomic profiles between pregnant and non-pregnant ewes, we identified 94 and 257 differentially expressed proteins (DEPs) in the endometrial caruncular and intercaruncular areas, respectively. Functional analysis showed that the DEPs were mainly associated with immune response, nutrient transport and utilization, as well as proteasome-mediated proteolysis. These analysis imply that dysfunction of these biological processes or pathways of DEP in the endometrium is highly associated with early pregnancy loss. In addition, many proteins that are essential for the establishment of pregnancy showed dysregulation in the endometrium of non-pregnant ewes. These proteins, as potential candidates, may contribute to early pregnancy loss.

  7. Three-Dimensional Design of a Non-Axisymmetric Periodic Permanent Magnet Focusing System

    CERN Document Server

    Chen Chi Ping; Radovinsky, Alexey; Zhou, Jing

    2005-01-01

    A three-dimensional (3D) design is presented of a non-axisymmetric periodic permanent magnet focusing system which will be used to focus a large-aspect-ratio, ellipse-shaped, space-charge-dominated electron beam. In this design, an analytic theory is used to specify the magnetic profile for beam transport. The OPERA3D code is used to compute and optimize a realizable magnet system. Results of the magnetic design are verified by two-dimensional particle-in-cell and three-dimensional trajectory simulations of beam propagation using PFB2D and OMNITRAK, respectively. Results of fabrication tolerance studies are discussed.

  8. Three-body models of the 6ΛΛHe and 9ΛBe hypernuclei with non-local interactions

    International Nuclear Information System (INIS)

    Theeten, M.; Baye, D.; Descouvemont, P.

    2005-01-01

    A three-body model involving non-local interactions is developed in configuration space. It is based on a hyperspherical-harmonics expansion and the Lagrange-mesh method. The 6 ΛΛ He and 9 Λ Be hypernuclei are studied as three-body αΛΛ and ααΛ systems. Recently proposed quark-model based ΛN and ΛΛ interactions are used. A non-local Λα interaction is obtained by folding the ΛN interaction with a Gaussian α density. Various phenomenological αα interactions are employed. The results agree within 1 keV with recent Faddeev calculations in momentum space. Energies and radii of 6 ΛΛ He and 9 Λ Be are compared with a purely local model. The B(E2) between the 9 Λ Be bound states is also calculated. The role of non-locality is discussed

  9. Patterns of non-verbal social interactions within intensive mathematics intervention contexts

    Science.gov (United States)

    Thomas, Jonathan Norris; Harkness, Shelly Sheats

    2016-06-01

    This study examined the non-verbal patterns of interaction within an intensive mathematics intervention context. Specifically, the authors draw on social constructivist worldview to examine a teacher's use of gesture in this setting. The teacher conducted a series of longitudinal teaching experiments with a small number of young, school-age children in the context of early arithmetic development. From these experiments, the authors gathered extensive video records of teaching practice and, from an inductive analysis of these records, identified three distinct patterns of teacher gesture: behavior eliciting, behavior suggesting, and behavior replicating. Awareness of their potential to influence students via gesture may prompt teachers to more closely attend to their own interactions with mathematical tools and take these teacher interactions into consideration when forming interpretations of students' cognition.

  10. Non-Gaussian path integration in self-interacting scalar field theories

    International Nuclear Information System (INIS)

    Kaya, Ali

    2004-01-01

    In self-interacting scalar field theories kinetic expansion is an alternative way of calculating the generating functional for Green's functions where the zeroth order non-Gaussian path integral becomes diagonal in x-space and reduces to the product of an ordinary integral at each point which can be evaluated exactly. We discuss how to deal with such functional integrals and propose a new perturbative expansion scheme which combines the elements of the kinetic expansion with the usual perturbation theory techniques. It is then shown that, when the cutoff dependences of the bare parameters in the potential are chosen to have a well defined non-Gaussian path integral without the kinetic term, the theory becomes trivial in the continuum limit

  11. Quasi-chemical approach for adsorption of mixtures with non-additive lateral interactions

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, O.A. [Instituto de Bionanotecnología (INBIONATEC-CONICET), Universidad Nacional de Santiago de Estero, RN 9 Km 1125 Villa el Zanjón, Santiago del Estero G4206XCP (Argentina); Pasinetti, P.M., E-mail: pmp@unsl.edu.ar [Departamento de Física, Instituto de Física Aplicada (INFAP), Universidad Nacional de San Luis—CONICET, Ejército de los Andes 950, D5700BWS San Luis (Argentina); Ramirez-Pastor, A.J. [Departamento de Física, Instituto de Física Aplicada (INFAP), Universidad Nacional de San Luis—CONICET, Ejército de los Andes 950, D5700BWS San Luis (Argentina)

    2017-01-15

    Highlights: • The classical quasi-chemical approach is generalized to model non-additive mixtures. • The formalism allows to obtain the partial isotherms and the differential heat of adsorption. • A rich variety of low-temperature phases is observed in the adsorbed layer. • Theoretical results show a good agreement with Monte Carlo simulations. - Abstract: The statistical thermodynamics of binary mixtures with non-additive lateral interactions was developed on a generalization in the spirit of the lattice-gas model and the classical quasi-chemical approximation (QCA). The traditional assumption of a strictly pairwise additive nearest-neighbors interaction is replaced by a more general one, namely that the bond linking a certain atom with any of its neighbors depends considerably on how many of them are actually present (or absent) on the sites in the first coordination shell of the atom. The total and partial adsorption isotherms are given for both attractive and repulsive lateral interactions between the adsorbed species. Interesting behaviors are observed and discussed in terms of the low-temperature phases formed in the system. Comparisons with Monte Carlo simulations are performed in order to test the validity of the theoretical model.

  12. Cellular and molecular interaction in HIV infection: A review | Timbo ...

    African Journals Online (AJOL)

    Objective: To review the cellular and molecular interactions between HIV and the host immune system that lead to full-blown AIDS. Data Sources: Published reports on HIV/host interaction during a fifteen year period beginning from 1987. Study selection: Only those studies involving humans and non-human primates were ...

  13. Hamiltonian bifurcation perspective on two interacting vortex pairs: From symmetric to asymmetric leapfrogging, period doubling, and chaos

    Science.gov (United States)

    Whitchurch, Brandon; Kevrekidis, Panayotis G.; Koukouloyannis, Vassilis

    2018-01-01

    In this work we study the dynamical behavior of two interacting vortex pairs, each one of them consisting of two point vortices with opposite circulation in the two-dimensional plane. The vortices are considered as effective particles and their interaction can be described in classical mechanics terms. We first construct a Poincaré section, for a typical value of the energy, in order to acquire a picture of the structure of the phase space of the system. We divide the phase space in different regions which correspond to qualitatively distinct motions and we demonstrate its different temporal evolution in the "real" vortex space. Our main emphasis is on the leapfrogging periodic orbit, around which we identify a region that we term the "leapfrogging envelope" which involves mostly regular motions, such as higher order periodic and quasiperiodic solutions. We also identify the chaotic region of the phase plane surrounding the leapfrogging envelope as well as the so-called walkabout and braiding motions. Varying the energy as our control parameter, we construct a bifurcation tree of the main leapfrogging solution and its instabilities, as well as the instabilities of its daughter branches. We identify the symmetry-breaking instability of the leapfrogging solution (in line with earlier works), and also obtain the corresponding asymmetric branches of periodic solutions. We then characterize their own instabilities (including period doubling ones) and bifurcations in an effort to provide a more systematic perspective towards the types of motions available to this dynamical system.

  14. Non-standard interactions with high-energy atmospheric neutrinos at IceCube

    Energy Technology Data Exchange (ETDEWEB)

    Salvado, Jordi; Mena, Olga; Palomares-Ruiz, Sergio; Rius, Nuria [Instituto de Física Corpuscular (IFIC), CSIC-Universitat de València,Apartado de Correos 22085, E-46071 Valencia (Spain)

    2017-01-31

    Non-standard interactions in the propagation of neutrinos in matter can lead to significant deviations from expectations within the standard neutrino oscillation framework and atmospheric neutrino detectors have been considered to set constraints. However, most previous works have focused on relatively low-energy atmospheric neutrino data. Here, we consider the one-year high-energy through-going muon data in IceCube, which has been already used to search for light sterile neutrinos, to constrain new interactions in the μτ-sector. In our analysis we include several systematic uncertainties on both, the atmospheric neutrino flux and on the detector properties, which are accounted for via nuisance parameters. After considering different primary cosmic-ray spectra and hadronic interaction models, we improve over previous analysis by using the latest data and showing that systematics currently affect very little the bound on the off-diagonal ε{sub μτ}, with the 90% credible interval given by −6.0×10{sup −3}<ε{sub μτ}<5.4×10{sup −3}, comparable to previous results. In addition, we also estimate the expected sensitivity after 10 years of collected data in IceCube and study the precision at which non-standard parameters could be determined for the case of ε{sub μτ} near its current bound.

  15. Biomarker Identification for Prostate Cancer and Lymph Node Metastasis from Microarray Data and Protein Interaction Network Using Gene Prioritization Method

    Directory of Open Access Journals (Sweden)

    Carlos Roberto Arias

    2012-01-01

    Full Text Available Finding a genetic disease-related gene is not a trivial task. Therefore, computational methods are needed to present clues to the biomedical community to explore genes that are more likely to be related to a specific disease as biomarker. We present biomarker identification problem using gene prioritization method called gene prioritization from microarray data based on shortest paths, extended with structural and biological properties and edge flux using voting scheme (GP-MIDAS-VXEF. The method is based on finding relevant interactions on protein interaction networks, then scoring the genes using shortest paths and topological analysis, integrating the results using a voting scheme and a biological boosting. We applied two experiments, one is prostate primary and normal samples and the other is prostate primary tumor with and without lymph nodes metastasis. We used 137 truly prostate cancer genes as benchmark. In the first experiment, GP-MIDAS-VXEF outperforms all the other state-of-the-art methods in the benchmark by retrieving the truest related genes from the candidate set in the top 50 scores found. We applied the same technique to infer the significant biomarkers in prostate cancer with lymph nodes metastasis which is not established well.

  16. Non-Covalent Interactions and Impact of Charge Penetration Effects in Linear Oligoacene Dimers and Single Crystals

    KAUST Repository

    Ryno, Sean

    2016-05-18

    Non-covalent interactions determine in large part the thermodynamic aspects of molecular packing in organic crystals. Using a combination of symmetry-adapted perturbation theory (SAPT) and classical multipole electrostatics, we describe the interaction potential energy surfaces for dimers of the oligoacene family, from benzene to hexacene. An analysis of these surfaces and a thorough assessment of dimers extracted from the reported crystal structures underline that high-order interactions (i.e., three-body non-additive interactions) must be considered in order to rationalize the details of the crystal structures. A comparison of the SAPT electrostatic energy with the multipole interaction energy demonstrates the importance of the contribution of charge penetration, which is shown to account for up to 50% of the total interaction energy in dimers extracted from the experimental single crystals; in the case of the most stable co-facial model dimers, this contribution is even larger than the total interaction energy. Our results highlight the importance of taking account of charge penetration in studies of the larger oligoacenes.

  17. Tsallis non-extensive statistical mechanics in the ionospheric detrended total electron content during quiet and storm periods

    Science.gov (United States)

    Ogunsua, B. O.; Laoye, J. A.

    2018-05-01

    In this paper, the Tsallis non-extensive q-statistics in ionospheric dynamics was investigated using the total electron content (TEC) obtained from two Global Positioning System (GPS) receiver stations. This investigation was carried out considering the geomagnetically quiet and storm periods. The micro density variation of the ionospheric total electron content was extracted from the TEC data by method of detrending. The detrended total electron content, which represent the variation in the internal dynamics of the system was further analyzed using for non-extensive statistical mechanics using the q-Gaussian methods. Our results reveals that for all the analyzed data sets the Tsallis Gaussian probability distribution (q-Gaussian) with value q > 1 were obtained. It was observed that there is no distinct difference in pattern between the values of qquiet and qstorm. However the values of q varies with geophysical conditions and possibly with local dynamics for the two stations. Also observed are the asymmetric pattern of the q-Gaussian and a highly significant level of correlation for the q-index values obtained for the storm periods compared to the quiet periods between the two GPS receiver stations where the TEC was measured. The factors responsible for this variation can be mostly attributed to the varying mechanisms resulting in the self-reorganization of the system dynamics during the storm periods. The result shows the existence of long range correlation for both quiet and storm periods for the two stations.

  18. Non-covalent interactions of cadmium sulphide and gold nanoparticles with DNA

    Science.gov (United States)

    Atay, Z.; Biver, T.; Corti, A.; Eltugral, N.; Lorenzini, E.; Masini, M.; Paolicchi, A.; Pucci, A.; Ruggeri, G.; Secco, F.; Venturini, M.

    2010-08-01

    Mercaptoethanol-capped CdS nanoparticles (CdSnp) and monohydroxy-(1-mercaptoundec-11-yl)tetraethylene-glycol-capped Au nanoparticles (Aunp) were synthesised, characterised and their interactions with DNA were investigated. Aunp are stable in different aqueous solvents, whereas CdSnp do precipitate in 0.1 M NaCl and form two different cluster types in 0.1 M NaNO3. As regards the CdSnp/DNA interaction, absorbance and fluorescence titrations, ethidium bromide displacement assays and gel electrophoresis experiments indicate that a non-covalent interaction between DNA and the CdSnp external surface does take place. The binding constant was evaluated to be equal to (2.2 ± 0.5) × 105 M-1. On the contrary, concerning Aunp, no direct interaction with DNA could be observed. Possible interaction with serum albumin was also checked, but no effects could be observed for either CdSnp or Aunp. Finally, short-time exposure of cultured cells to nanoparticles revealed the ability of CdSnp to enter the cells and allocate both in cytosol and nucleus, thus promoting cell proliferation at low concentration ( p resulted in a significant inhibition of cell growth, accompanied by apoptotic cell death. Aunp neither enter the cells, nor do affect cell proliferation. In conclusion, our data indicate that CdSnp can strongly interact with living cells and nucleic acid while no effects or interactions were observed for Aunp.

  19. A Hybrid Optimized Weighted Minimum Spanning Tree for the Shortest Intrapath Selection in Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Matheswaran Saravanan

    2014-01-01

    Full Text Available Wireless sensor network (WSN consists of sensor nodes that need energy efficient routing techniques as they have limited battery power, computing, and storage resources. WSN routing protocols should enable reliable multihop communication with energy constraints. Clustering is an effective way to reduce overheads and when this is aided by effective resource allocation, it results in reduced energy consumption. In this work, a novel hybrid evolutionary algorithm called Bee Algorithm-Simulated Annealing Weighted Minimal Spanning Tree (BASA-WMST routing is proposed in which randomly deployed sensor nodes are split into the best possible number of independent clusters with cluster head and optimal route. The former gathers data from sensors belonging to the cluster, forwarding them to the sink. The shortest intrapath selection for the cluster is selected using Weighted Minimum Spanning Tree (WMST. The proposed algorithm computes the distance-based Minimum Spanning Tree (MST of the weighted graph for the multihop network. The weights are dynamically changed based on the energy level of each sensor during route selection and optimized using the proposed bee algorithm simulated annealing algorithm.

  20. Tailoring of the electrical and thermal properties using ultra-short period non-symmetric superlattices

    Directory of Open Access Journals (Sweden)

    Paulina Komar

    2016-10-01

    Full Text Available Thermoelectric modules based on half-Heusler compounds offer a cheap and clean way to create eco-friendly electrical energy from waste heat. Here we study the impact of the period composition on the electrical and thermal properties in non-symmetric superlattices, where the ratio of components varies according to (TiNiSnn:(HfNiSn6−n, and 0 ⩽ n ⩽ 6 unit cells. The thermal conductivity (κ showed a strong dependence on the material content achieving a minimum value for n = 3, whereas the highest value of the figure of merit ZT was achieved for n = 4. The measured κ can be well modeled using non-symmetric strain relaxation applied to the model of the series of thermal resistances.

  1. 'Doctor' or 'darling'? Decoding the communication partner from ECoG of the anterior temporal lobe during non-experimental, real-life social interaction

    Directory of Open Access Journals (Sweden)

    Johanna eDerix

    2012-09-01

    Full Text Available Human brain processes underlying real-life social interaction in everyday situations have been difficult to study and have, until now, remained largely unknown. Here, we investigated whether electrocorticography (ECoG recorded for pre-neurosurgical diagnostics during the daily hospital life of epilepsy patients could provide a way to elucidate the neural correlates of non-experimental social interaction. We identified time periods in which patients were involved in conversations with either their respective life partners (Condition 1; C1 or attending physicians (Condition 2; C2. These two conditions can be expected to differentially involve subfunctions of social interaction which have been associated with activity in the anterior temporal lobe (ATL, including the temporal poles (TP. Therefore, we specifically focused on ECoG recordings from this brain region and investigated spectral power modulations in the alpha (8-12 Hz and theta (3-5 Hz frequency ranges, which have been previously assumed to play an important role in the processing of social interaction. We hypothesized that brain activity in this region might be sensitive to differences in the two interaction situations and tested whether these differences can be detected by single-trial decoding. Condition-specific effects in both theta and alpha bands were observed: the left and right TP exclusively showed increased power in C1 compared to C2, whereas more posterior parts of the ATL exhibited similar (C1 > C2 and also contrary (C2 > C1 effects. Single-trial decoding accuracies for classification of these effects were highly above chance. Our findings demonstrate that it is possible to study the neural correlates of human social interaction in non-experimental conditions. Decoding the identity of the communication partner and adjusting the speech output accordingly may be useful in the emerging field of brain- machine interfacing for restoration of expressive speech.

  2. Interaction of femtosecond X-ray pulses with periodical multilayer structures

    International Nuclear Information System (INIS)

    Ksenzov, Dmitry

    2010-01-01

    The VUV Free Electron Laser FLASH operates in soft X-ray range and produces high-intensive pulse trains with few tens femtoseconds duration. The transversely fully coherent beam will open new experiments in solid state physics which can not be studied with present radiation sources. The study of the time dependent response of the multilayer to the X-ray pulse can provide insights into the process of interaction of highly intense FEL radiation with matter. To test the influence of electron excitation on the optical properties of boron carbide, the refractive index of B 4 C was measured near B K-edge by energy-resolved photon-in-photon-out method probing a Bragg reflection from periodical multilayers. The measured data clearly show that the variation of the fine structure of the Kabsorption edges due to the chemical nature of the absorber element. The knowledge obtained from experiments with continuous radiation was used to design the respective experiments with pulse from the FEL. In my thesis, it is proposed that the geometrical setup, where the incident pulse arrives from the FEL under the angle close to the 1st order ML Bragg peak, provides the most valuable information. Preliminary simulation considering form factors of neutral and ionized boron showed that due to ionization, pronounced changes in the reflectivity curve are expected. The proposed scheme can be the powerful tool to study the various processes within the electronic subsystem of the FEL pulse interaction with matter. This type of investigations gives a deep understanding of the nature of the electronic excitation and the recombination at the femtosecond scale. (orig.)

  3. Interaction of femtosecond X-ray pulses with periodical multilayer structures

    Energy Technology Data Exchange (ETDEWEB)

    Ksenzov, Dmitry

    2010-07-01

    The VUV Free Electron Laser FLASH operates in soft X-ray range and produces high-intensive pulse trains with few tens femtoseconds duration. The transversely fully coherent beam will open new experiments in solid state physics which can not be studied with present radiation sources. The study of the time dependent response of the multilayer to the X-ray pulse can provide insights into the process of interaction of highly intense FEL radiation with matter. To test the influence of electron excitation on the optical properties of boron carbide, the refractive index of B{sub 4}C was measured near B K-edge by energy-resolved photon-in-photon-out method probing a Bragg reflection from periodical multilayers. The measured data clearly show that the variation of the fine structure of the Kabsorption edges due to the chemical nature of the absorber element. The knowledge obtained from experiments with continuous radiation was used to design the respective experiments with pulse from the FEL. In my thesis, it is proposed that the geometrical setup, where the incident pulse arrives from the FEL under the angle close to the 1st order ML Bragg peak, provides the most valuable information. Preliminary simulation considering form factors of neutral and ionized boron showed that due to ionization, pronounced changes in the reflectivity curve are expected. The proposed scheme can be the powerful tool to study the various processes within the electronic subsystem of the FEL pulse interaction with matter. This type of investigations gives a deep understanding of the nature of the electronic excitation and the recombination at the femtosecond scale. (orig.)

  4. Perceptual interaction between carrier periodicity and amplitude modulation in broadband stimuli: A comparison of the autocorrelation and modulation-filterbank model

    DEFF Research Database (Denmark)

    Stein, A.; Ewert, Stephan; Wiegrebe, L.

    2005-01-01

    , autocorrelation is applied. Considering the large overlap in pitch and modulation perception, this is not parsimonious. Two experiments are presented to investigate the interaction between carrier periodicity, which produces strong pitch sensations, and envelope periodicity using broadband stimuli. Results show......Recent temporal models of pitch and amplitude modulation perception converge on a relatively realistic implementation of cochlear processing followed by a temporal analysis of periodicity. However, for modulation perception, a modulation filterbank is applied whereas for pitch perception...

  5. An executable model of the interaction between verbal and non-verbal communication.

    NARCIS (Netherlands)

    Jonker, C.M.; Treur, J.; Wijngaards, W.C.A.

    2000-01-01

    In this paper an executable generic process model is proposed for combined verbal and non-verbal communication processes and their interaction. The model has been formalised by three-levelled partial temporal models, covering both the material and mental processes and their relations. The generic

  6. An Executable Model of the Interaction between Verbal and Non-Verbal Communication

    NARCIS (Netherlands)

    Jonker, C.M.; Treur, J.; Wijngaards, W.C.A.; Dignum, F.; Greaves, M.

    2000-01-01

    In this paper an executable generic process model is proposed for combined verbal and non-verbal communication processes and their interaction. The model has been formalised by three-levelled partial temporal models, covering both the material and mental processes and their relations. The generic

  7. Period doubling of azimuthal oscillations on a non-neutral magnetized electron column

    International Nuclear Information System (INIS)

    Boswell, R.W.

    1985-01-01

    The low-frequency azimuthal oscillations on a non-neutral magnetized electron column of very low density are investigated. A perturbation analysis of the slow mode of the rigid rotator equilibrium is developed to illustrate the nature of large-amplitude fundamental-mode oscillations. The results of this theoretical analysis show two important characteristics: firstly, as the perturbation amplitude is increased the wave form ceases to be purely sinusoidal and shows period doubling. Secondly, above a certain threshold, all harmonics of the wave grow and the wave breaks. The results of the former are compared with a simple electron beam experiment and are found to be in good qualitative agreement. (author)

  8. An Exploratory Case Study of Young Children's Interactive Play Behaviours with a Non-English Speaking Child

    Science.gov (United States)

    Lee, Joohi; Md-Yunus, Sham'ah; Son, Won In; Meadows, Michelle

    2009-01-01

    This study is an examination of preschool-age English speaking children's interactive play behaviours with a non-English speaking child (NEC). The play types of a NEC were reported using the Parten's categories of solitary, parallel and interactive play. In addition, English-speaking children's interactive play with a NEC were reported in this…

  9. Differentiated Staffing and Non-Teamed Organizational Structures as They Affect Elementary School Teacher-Pupil Interaction.

    Science.gov (United States)

    Petrie, Thomas A.; And Others

    A study was conducted of the differences in the frequency of selected student-teacher interaction in differentiated staffs and in non-teamed schools. The interaction processes studied were synthesized from Erikson's four stages of childhood: student behaviors--information processing, choice-making, reflection, problem solving, and procedures or…

  10. Interpersonal Interactions in Instrumental Lessons: Teacher/Student Verbal and Non-Verbal Behaviours

    Science.gov (United States)

    Zhukov, Katie

    2013-01-01

    This study examined verbal and non-verbal teacher/student interpersonal interactions in higher education instrumental music lessons. Twenty-four lessons were videotaped and teacher/student behaviours were analysed using a researcher-designed instrument. The findings indicate predominance of student and teacher joke among the verbal behaviours with…

  11. Non-specific interactions are sufficient to explain the position of heterochromatic chromocenters and nucleoli in interphase nuclei

    NARCIS (Netherlands)

    Nooijer, de S.; Wellink, J.; Mulder, B.; Bisseling, T.

    2009-01-01

    The organization of the eukaryote nucleus into functional compartments arises by self-organization both through specific protein–protein and protein–DNA interactions and non-specific interactions that lead to entropic effects, such as e.g. depletion attraction. While many specific interactions have

  12. Iraqi architecture in mogul period

    Directory of Open Access Journals (Sweden)

    Hasan Shatha

    2018-01-01

    Full Text Available Iraqi architecture have many periods passed through it until now, each on from these periods have it is architectural style, also through time these styles interacted among us, to creating kind of space forming, space relationships, and architectural elements (detailed treatments, the research problem being from the multi interacted architectural styles causing some of confused of general characteristic to every style, that we could distinguish by it. Research tries to study architecture style through Mogul Conquest to Baghdad. Aim of research follow main characteristic for this architectural style in the Mogul periods on the level of form, elements, and treatments. Research depending on descriptive and analytical all buildings belong to this period, so from analyzing there style by, general form for building, architectural elements, and it architectural treatment, therefore; repeating this procedures to every building we get some similarities, from these similarities we can making conclusion about pure characteristic of the style of these period. Other side, we also discover some Dissimilar in the building periods, these will lead research to make what interacting among styles in this period, after all that we can drew clearly main characteristic of Architectural Style for Mogul Conquest in Baghdad

  13. Non-fragile consensus algorithms for a network of diffusion PDEs with boundary local interaction

    Science.gov (United States)

    Xiong, Jun; Li, Junmin

    2017-07-01

    In this study, non-fragile consensus algorithm is proposed to solve the average consensus problem of a network of diffusion PDEs, modelled by boundary controlled heat equations. The problem deals with the case where the Neumann-type boundary controllers are corrupted by additive persistent disturbances. To achieve consensus between agents, a linear local interaction rule addressing this requirement is given. The proposed local interaction rules are analysed by applying a Lyapunov-based approach. The multiplicative and additive non-fragile feedback control algorithms are designed and sufficient conditions for the consensus of the multi-agent systems are presented in terms of linear matrix inequalities, respectively. Simulation results are presented to support the effectiveness of the proposed algorithms.

  14. Using coloured roots to study root interaction and competition in intercropped legumes and non-legumes

    DEFF Research Database (Denmark)

    Tosti, Giacomo; Thorup-Kristensen, Kristian

    2010-01-01

    if a species with coloured roots can be used to examine the interaction in a legume-non-legume intercropping system; (ii) to verify the importance of initial root growth on the successive root development of mixture component plants; (iii) to test if the root interaction in the shallow layers has consequences...

  15. Non-periodic preventive maintenance with reliability thresholds for complex repairable systems

    International Nuclear Information System (INIS)

    Lin, Zu-Liang; Huang, Yeu-Shiang; Fang, Chih-Chiang

    2015-01-01

    In general, a non-periodic condition-based PM policy with different condition variables is often more effective than a periodic age-based policy for deteriorating complex repairable systems. In this study, system reliability is estimated and used as the condition variable, and three reliability-based PM models are then developed with consideration of different scenarios which can assist in evaluating the maintenance cost for each scenario. The proposed approach provides the optimal reliability thresholds and PM schedules in advance by which the system availability and quality can be ensured and the organizational resources can be well prepared and managed. The results of the sensitivity anlysis indicate that PM activities performed at a high reliability threshold can not only significantly improve the system availability but also efficiently extend the system lifetime, although such a PM strategy is more costly than that for a low reliabiltiy threshold. The optimal reliability threshold increases along with the number of PM activities to prevent future breakdowns caused by severe deterioration, and thus substantially reduces repair costs. - Highlights: • The PM problems for repairable deteriorating systems are formulated. • The structural properties of the proposed PM models are investigated. • The corresponding algorithms to find the optimal PM strategies are provided. • Imperfect PM activities are allowed to reduce the occurences of breakdowns. • Provide managers with insights about the critical factors in the planning stage

  16. K-Shortest-Path-Based Evacuation Routing with Police Resource Allocation in City Transportation Networks.

    Directory of Open Access Journals (Sweden)

    Yunyue He

    Full Text Available Emergency evacuation aims to transport people from dangerous places to safe shelters as quickly as possible. Police play an important role in the evacuation process, as they can handle traffic accidents immediately and help people move smoothly on roads. This paper investigates an evacuation routing problem that involves police resource allocation. We propose a novel k-th-shortest-path-based technique that uses explicit congestion control to optimize evacuation routing and police resource allocation. A nonlinear mixed-integer programming model is presented to formulate the problem. The model's objective is to minimize the overall evacuation clearance time. Two algorithms are given to solve the problem. The first one linearizes the original model and solves the linearized problem with CPLEX. The second one is a heuristic algorithm that uses a police resource utilization efficiency index to directly solve the original model. This police resource utilization efficiency index significantly aids in the evaluation of road links from an evacuation throughput perspective. The proposed algorithms are tested with a number of examples based on real data from cities of different sizes. The computational results show that the police resource utilization efficiency index is very helpful in finding near-optimal solutions. Additionally, comparing the performance of the heuristic algorithm and the linearization method by using randomly generated examples indicates that the efficiency of the heuristic algorithm is superior.

  17. Interacting entropy-corrected new agegraphic dark energy in the non-flat universe

    Energy Technology Data Exchange (ETDEWEB)

    Karami, Kayoomars [Department of Physics, University of Kurdistan, Pasdaran Street, Sanandaj (Iran, Islamic Republic of); Sorouri, Arash, E-mail: KKarami@uok.ac.i [Research Institute for Astronomy and Astrophysics of Maragha (RIAAM), Maragha (Iran, Islamic Republic of)

    2010-08-15

    Here, we consider the entropy-corrected version of the new agegraphic dark energy (NADE) model in the non-flat Friedmann-Robertson-Walker universe. We derive the exact differential equation that determines the evolution of the entropy-corrected NADE density parameter in the presence of interaction with dark matter. We also obtain the equation of state and deceleration parameters and present a necessary condition for the selected model to cross the phantom divide. Moreover, we reconstruct the potential and the dynamics of the phantom scalar field according to the evolutionary behavior of the interacting entropy-corrected new agegraphic model.

  18. The role of interaction of verbal and non-verbal means of communication in different types of discourse

    OpenAIRE

    Orlova M. А.

    2010-01-01

    Communication relies on verbal and non-verbal interaction. To be most effective, group members need to improve verbal and non-verbal communication. Non-verbal communication fulfills functions within groups that are sometimes difficult to communicate verbally. But interpreting non-verbal messages requires a great deal of skill because multiple meanings abound in these messages.

  19. A test to evaluation non-linear soil structure interaction

    International Nuclear Information System (INIS)

    Hagiwara, T.; Kitada, Y.

    2005-01-01

    JNES is planning a new project to study non-linear soil-structure interaction (SSI) effect under large earthquake ground motions equivalent to and/or over a design earthquake ground motion of S2. Concerning the SSI test, it is pointed out that handling of the scale effect of the specimen taking into account the surrounding soil on the earthquake response evaluation to the actual structure is essential issue for the scaled model test. Thus, for the test, the largest specimen possible and the biggest input motion possible are necessary. Taking into account the above issues, new test methodology, which utilizes artificial earthquake ground motion, is considered desirable if it can be performed at a realistic cost. With this motivation, we have studied the test methodology which applying blasting power as for a big earthquake ground motion. The information from a coalmine company in the U.S.A. indicates that the works performed in the surface coalmine to blast a rock covering a coal layer generates a big artificial ground motion, which is similar to earthquake ground motion. Application of this artificial earthquake ground motion for the SSI test is considered very promising because the blasting work is carried out periodically for mining coal so that we can apply artificial motions generated by the work if we construct a building model at a closed point to the blasting work area. The major purposes of the test are to understand (a) basic earthquake response characteristics of a Nuclear Power Plant (NPP) reactor building when a large earthquake strikes the NPP site and (b) nonlinear characteristics of SSI phenomenon during a big earthquake. In the paper of ICONE-13, we will introduce the test method and basic characteristics of measured artificial ground motions generated by the blasting works on an actual site. (authors)

  20. Imaging contrast and tip-sample interaction of non-contact amplitude modulation atomic force microscopy with Q -control

    International Nuclear Information System (INIS)

    Shi, Shuai; Guo, Dan; Luo, Jianbin

    2017-01-01

    Active quality factor ( Q ) exhibits many promising properties in dynamic atomic force microscopy. Energy dissipation and image contrasts are investigated in the non-contact amplitude modulation atomic force microscopy (AM-AFM) with an active Q -control circuit in the ambient air environment. Dissipated power and virial were calculated to compare the highly nonlinear interaction of tip-sample and image contrasts with different Q gain values. Greater free amplitudes and lower effective Q values show better contrasts for the same setpoint ratio. Active quality factor also can be employed to change tip-sample interaction force in non-contact regime. It is meaningful that non-destructive and better contrast images can be realized in non-contact AM-AFM by applying an active Q -control to the dynamic system. (paper)

  1. Fluid-structure interactions in one-dimensional linear cases

    International Nuclear Information System (INIS)

    Schumann, U.

    1979-01-01

    The interaction of pressure waves in a pipe with an elastic endwall (piston) is analyzed using a linear ('acoustic') model. Two transient and two periodic cases are investigated. In the transient cases the motions are initiated by either a sudden pressure drop at the opeen end (breaking membrane) or by a sudden release of the piston from a non-equilibrium position ('snapback'); in the latter case the other end of the pipe is closed. In the periodic cases harmonic oscillations of the piston and the fluid are investigated with the other end of the pipe being either closed or open (kept at constant pressure). The problem is characterized by three non-dimensional numbers (e.g.: Mach-, Strouhal-, and an interaction-number). The solution of the wave equation for the pressure accounting for the coupling to the structure can be reduced analytically to the problem of integrating one ordinary differential equation of second order in time. This differential equation in turn can be integrated analytically at least for a certain time period. At later times this ordinary differential equation is integrated numerically. For the periodic cases eigenvalue-problems arise with an infinite number of solutions. The first few eigensolutions are given. (orig./RW) [de

  2. Distribution of shortest path lengths in a class of node duplication network models

    Science.gov (United States)

    Steinbock, Chanania; Biham, Ofer; Katzav, Eytan

    2017-09-01

    We present analytical results for the distribution of shortest path lengths (DSPL) in a network growth model which evolves by node duplication (ND). The model captures essential properties of the structure and growth dynamics of social networks, acquaintance networks, and scientific citation networks, where duplication mechanisms play a major role. Starting from an initial seed network, at each time step a random node, referred to as a mother node, is selected for duplication. Its daughter node is added to the network, forming a link to the mother node, and with probability p to each one of its neighbors. The degree distribution of the resulting network turns out to follow a power-law distribution, thus the ND network is a scale-free network. To calculate the DSPL we derive a master equation for the time evolution of the probability Pt(L =ℓ ) , ℓ =1 ,2 ,⋯ , where L is the distance between a pair of nodes and t is the time. Finding an exact analytical solution of the master equation, we obtain a closed form expression for Pt(L =ℓ ) . The mean distance 〈L〉 t and the diameter Δt are found to scale like lnt , namely, the ND network is a small-world network. The variance of the DSPL is also found to scale like lnt . Interestingly, the mean distance and the diameter exhibit properties of a small-world network, rather than the ultrasmall-world network behavior observed in other scale-free networks, in which 〈L〉 t˜lnlnt .

  3. Predicting haemodynamic networks using electrophysiology: The role of non-linear and cross-frequency interactions

    Science.gov (United States)

    Tewarie, P.; Bright, M.G.; Hillebrand, A.; Robson, S.E.; Gascoyne, L.E.; Morris, P.G.; Meier, J.; Van Mieghem, P.; Brookes, M.J.

    2016-01-01

    Understanding the electrophysiological basis of resting state networks (RSNs) in the human brain is a critical step towards elucidating how inter-areal connectivity supports healthy brain function. In recent years, the relationship between RSNs (typically measured using haemodynamic signals) and electrophysiology has been explored using functional Magnetic Resonance Imaging (fMRI) and magnetoencephalography (MEG). Significant progress has been made, with similar spatial structure observable in both modalities. However, there is a pressing need to understand this relationship beyond simple visual similarity of RSN patterns. Here, we introduce a mathematical model to predict fMRI-based RSNs using MEG. Our unique model, based upon a multivariate Taylor series, incorporates both phase and amplitude based MEG connectivity metrics, as well as linear and non-linear interactions within and between neural oscillations measured in multiple frequency bands. We show that including non-linear interactions, multiple frequency bands and cross-frequency terms significantly improves fMRI network prediction. This shows that fMRI connectivity is not only the result of direct electrophysiological connections, but is also driven by the overlap of connectivity profiles between separate regions. Our results indicate that a complete understanding of the electrophysiological basis of RSNs goes beyond simple frequency-specific analysis, and further exploration of non-linear and cross-frequency interactions will shed new light on distributed network connectivity, and its perturbation in pathology. PMID:26827811

  4. Non-Watson–Crick interactions between PNA and DNA inhibit the ATPase activity of bacteriophage T4 Dda helicase

    Science.gov (United States)

    Tackett, Alan J.; Corey, David R.; Raney, Kevin D.

    2002-01-01

    Peptide nucleic acid (PNA) is a DNA mimic in which the nucleobases are linked by an N-(2-aminoethyl) glycine backbone. Here we report that PNA can interact with single-stranded DNA (ssDNA) in a non-sequence-specific fashion. We observed that a 15mer PNA inhibited the ssDNA-stimulated ATPase activity of a bacteriophage T4 helicase, Dda. Surprisingly, when a fluorescein-labeled 15mer PNA was used in binding studies no interaction was observed between PNA and Dda. However, fluorescence polarization did reveal non-sequence-specific interactions between PNA and ssDNA. Thus, the inhibition of ATPase activity of Dda appears to result from depletion of the available ssDNA due to non-Watson–Crick binding of PNA to ssDNA. Inhibition of the ssDNA-stimulated ATPase activity was observed for several PNAs of varying length and sequence. To study the basis for this phenomenon, we examined self-aggregation by PNAs. The 15mer PNA readily self-aggregates to the point of precipitation. Since PNAs are hydrophobic, they aggregate more than DNA or RNA, making the study of this phenomenon essential for understanding the properties of PNA. Non-sequence-specific interactions between PNA and ssDNA were observed at moderate concentrations of PNA, suggesting that such interactions should be considered for antisense and antigene applications. PMID:11842106

  5. On the decomposition of a dynamical system into non-interacting subsystems.

    Science.gov (United States)

    Rosen, R.

    1972-01-01

    It is shown that, under rather general conditions, it is possible to formally decompose the dynamics of an n-dimensional dynamical system into a number of non-interacting subsystems. It is shown that these decompositions are in general not simply related to the kinds of observational procedures in terms of which the original state variables of the system are defined. Some consequences of this construction for reductionism in biology are discussed.

  6. Electrostatic interactions in finite systems treated with periodic boundary conditions: application to linear-scaling density functional theory.

    Science.gov (United States)

    Hine, Nicholas D M; Dziedzic, Jacek; Haynes, Peter D; Skylaris, Chris-Kriton

    2011-11-28

    We present a comparison of methods for treating the electrostatic interactions of finite, isolated systems within periodic boundary conditions (PBCs), within density functional theory (DFT), with particular emphasis on linear-scaling (LS) DFT. Often, PBCs are not physically realistic but are an unavoidable consequence of the choice of basis set and the efficacy of using Fourier transforms to compute the Hartree potential. In such cases the effects of PBCs on the calculations need to be avoided, so that the results obtained represent the open rather than the periodic boundary. The very large systems encountered in LS-DFT make the demands of the supercell approximation for isolated systems more difficult to manage, and we show cases where the open boundary (infinite cell) result cannot be obtained from extrapolation of calculations from periodic cells of increasing size. We discuss, implement, and test three very different approaches for overcoming or circumventing the effects of PBCs: truncation of the Coulomb interaction combined with padding of the simulation cell, approaches based on the minimum image convention, and the explicit use of open boundary conditions (OBCs). We have implemented these approaches in the ONETEP LS-DFT program and applied them to a range of systems, including a polar nanorod and a protein. We compare their accuracy, complexity, and rate of convergence with simulation cell size. We demonstrate that corrective approaches within PBCs can achieve the OBC result more efficiently and accurately than pure OBC approaches.

  7. THE BARRIERS FOR PROLIFERATION OF INTERACTIVE TELEVISION (ITV IN AUSTRALIA IN THE PERIOD 1999-2007

    Directory of Open Access Journals (Sweden)

    Maria J. Bora

    2012-04-01

    Full Text Available Interactive television (iTV could well be described as a rising research area. The digitalization of networks, as well as broadband penetration, makes it once again a contemporary issue. However, it can hardly be called an overworked area of Australian television studies. This article assesses multiple reasons behind the Australian failure to adopt this technology in the period 1999-2007. iTV did not open feasible revenue streams for broadcasters. Its role was complementary to the digital TV services offered by current incumbent providers. The interactive potential of the Internet supported by users’ engagement started to fulfil the promises of iTV and offered more collaborative service propositions. Still, at this point, neither TV nor the Internet provides fully viable business models for iTV. Instead there has been a flux of online and offline revenue models and continuing uncertainty about the future of media.

  8. Quantitative analysis of tip-sample interaction in non-contact scanning force spectroscopy

    International Nuclear Information System (INIS)

    Palacios-Lidon, Elisa; Colchero, Jaime

    2006-01-01

    Quantitative characterization of tip-sample interaction in scanning force microscopy is fundamental for optimum image acquisition as well as data interpretation. In this work we discuss how to characterize the electrostatic and van der Waals contribution to tip-sample interaction in non-contact scanning force microscopy precisely. The spectroscopic technique presented is based on the simultaneous measurement of cantilever deflection, oscillation amplitude and frequency shift as a function of tip-sample voltage and tip-sample distance as well as on advanced data processing. Data are acquired at a fixed lateral position as interaction images, with the bias voltage as fast scan, and tip-sample distance as slow scan. Due to the quadratic dependence of the electrostatic interaction with tip-sample voltage the van der Waals force can be separated from the electrostatic force. Using appropriate data processing, the van der Waals interaction, the capacitance and the contact potential can be determined as a function of tip-sample distance. The measurement of resonance frequency shift yields very high signal to noise ratio and the absolute calibration of the measured quantities, while the acquisition of cantilever deflection allows the determination of the tip-sample distance

  9. Experiment and numerical simulation on the characteristics of fluid–structure interactions of non-rigid airships

    Directory of Open Access Journals (Sweden)

    Xiaocui Wu

    2015-11-01

    Full Text Available Fluid–structure interaction is an important issue for non-rigid airships with inflated envelopes. In this study, a wind tunnel test is conducted, and a loosely coupled procedure is correspondingly established for numerical simulation based on computational fluid dynamics and nonlinear finite element analysis methods. The typical results of the numerical simulation and wind tunnel experiment, including the overall lift and deformation, are in good agreement with each other. The results obtained indicate that the effect of fluid–structure interaction is noticeable and should be considered for non-rigid airships. Flow-induced deformation can further intensify the upward lift force and pitching moment, which can lead to a large deformation. Under a wind speed of 15 m/s, the lift force of the non-rigid model is increased to approximately 60% compared with that of the rigid model under a high angle of attack.

  10. Interacting polytropic gas model of phantom dark energy in non-flat universe

    International Nuclear Information System (INIS)

    Karami, K.; Ghaffari, S.; Fehri, J.

    2009-01-01

    By introducing the polytropic gas model of interacting dark energy, we obtain the equation of state for the polytropic gas energy density in a non-flat universe. We show that for an even polytropic index by choosing K>Ba (3)/(n) , one can obtain ω Λ eff <-1, which corresponds to a universe dominated by phantom dark energy. (orig.)

  11. Experimental investigation of gravity wave turbulence and of non-linear four wave interactions..

    Science.gov (United States)

    Berhanu, Michael

    2017-04-01

    Using the large basins of the Ecole Centrale de Nantes (France), non-linear interactions of gravity surface waves are experimentally investigated. In a first part we study statistical properties of a random wave field regarding the insights from the Wave Turbulence Theory. In particular freely decaying gravity wave turbulence is generated in a closed basin. No self-similar decay of the spectrum is observed, whereas its Fourier modes decay first as a time power law due to nonl-inear mechanisms, and then exponentially due to linear viscous damping. We estimate the linear, non-linear and dissipative time scales to test the time scale separation. By estimation of the mean energy flux from the initial decay of wave energy, the Kolmogorov-Zakharov constant of the weak turbulence theory is evaluated. In a second part, resonant interactions of oblique surface gravity waves in a large basin are studied. We generate two oblique waves crossing at an acute angle. These mother waves mutually interact and give birth to a resonant wave whose properties (growth rate, resonant response curve and phase locking) are fully characterized. All our experimental results are found in good quantitative agreement with four-wave interaction theory. L. Deike, B. Miquel, P. Gutiérrez, T. Jamin, B. Semin, M. Berhanu, E. Falcon and F. Bonnefoy, Role of the basin boundary conditions in gravity wave turbulence, Journal of Fluid Mechanics 781, 196 (2015) F. Bonnefoy, F. Haudin, G. Michel, B. Semin, T. Humbert, S. Aumaître, M. Berhanu and E. Falcon, Observation of resonant interactions among surface gravity waves, Journal of Fluid Mechanics (Rapids) 805, R3 (2016)

  12. Prediction of leakage current of non-ceramic insulators in early aging period

    Energy Technology Data Exchange (ETDEWEB)

    El-Hag, Ayman H. [Electrical Engineering Department, American University of Sharjah, Sharjah (United Arab Emirates); Jahromi, Ali Naderian [Kinectrics Inc., Transmission and Distribution Technologies, Toronto (Canada); Sanaye-Pasand, Majid [Electrical and Computer Engineering Department, University of Tehran (Iran)

    2008-10-15

    The paper presents a neural network based prediction technique for the leakage current (LC) of non-ceramic insulators during salt-fog test. Nearly 50 distribution class silicone rubber (SIR) insulators with three different voltage classes have been tested in a salt-fog chamber, where the LC has been continuously recorded for at least 100 h. A boundary for early aging period is defined by the rate of change of the LC instead of a fixed threshold value. Consequently, the Gaussian radial basis network has been adopted to predict the level of LC at the early stage of aging of the SIR insulators and is compared with a classical network. The initial values of LC and its rate of change at 10 min intervals for the first 5 h are selected as the input to the network, and the final value of LC of the early aging period is considered as the output of the network. It is found that Gaussian radial basis function network with a random optimizing training method is an appropriate network to predict the LC with a 3.5-5.3% accuracy, if the training data and the testing data are selected from the same type of SIR insulators. (author)

  13. Multiple analytical approaches reveal distinct gene-environment interactions in smokers and non smokers in lung cancer.

    Directory of Open Access Journals (Sweden)

    Rakhshan Ihsan

    Full Text Available Complex disease such as cancer results from interactions of multiple genetic and environmental factors. Studying these factors singularly cannot explain the underlying pathogenetic mechanism of the disease. Multi-analytical approach, including logistic regression (LR, classification and regression tree (CART and multifactor dimensionality reduction (MDR, was applied in 188 lung cancer cases and 290 controls to explore high order interactions among xenobiotic metabolizing genes and environmental risk factors. Smoking was identified as the predominant risk factor by all three analytical approaches. Individually, CYP1A1*2A polymorphism was significantly associated with increased lung cancer risk (OR = 1.69;95%CI = 1.11-2.59,p = 0.01, whereas EPHX1 Tyr113His and SULT1A1 Arg213His conferred reduced risk (OR = 0.40;95%CI = 0.25-0.65,p<0.001 and OR = 0.51;95%CI = 0.33-0.78,p = 0.002 respectively. In smokers, EPHX1 Tyr113His and SULT1A1 Arg213His polymorphisms reduced the risk of lung cancer, whereas CYP1A1*2A, CYP1A1*2C and GSTP1 Ile105Val imparted increased risk in non-smokers only. While exploring non-linear interactions through CART analysis, smokers carrying the combination of EPHX1 113TC (Tyr/His, SULT1A1 213GG (Arg/Arg or AA (His/His and GSTM1 null genotypes showed the highest risk for lung cancer (OR = 3.73;95%CI = 1.33-10.55,p = 0.006, whereas combined effect of CYP1A1*2A 6235CC or TC, SULT1A1 213GG (Arg/Arg and betel quid chewing showed maximum risk in non-smokers (OR = 2.93;95%CI = 1.15-7.51,p = 0.01. MDR analysis identified two distinct predictor models for the risk of lung cancer in smokers (tobacco chewing, EPHX1 Tyr113His, and SULT1A1 Arg213His and non-smokers (CYP1A1*2A, GSTP1 Ile105Val and SULT1A1 Arg213His with testing balance accuracy (TBA of 0.6436 and 0.6677 respectively. Interaction entropy interpretations of MDR results showed non-additive interactions of tobacco chewing with

  14. The nonlinear ambipolar drift and periodic structure of non-self-sustained discharge

    International Nuclear Information System (INIS)

    Dem'yanov, A.V.; Mazalov, D.A.; Napartovich, A.P.

    1995-01-01

    Gas discharge is well known to be strongly nonlinear self-organizing system. The diverse nonlinear structures, observed at different conditions (arc, stationary and non-stationary strata, hot spot patterns on the electrodes and so on), are usually explained by the theory taking into account the processes of diffusion and thermoconductivity. In plasma of high pressure discharge these processes become negligible within the characteristic intervals. At these conditions electron drift becomes the main process. Owing to the continuity of full current and plasma quasineutrality there appear effective flows of convective type with the rate depending on the concentration of charged particles. It is this reason that is responsible for the observed structure of the non-moving luminous layers in non-self-sustained discharge in 10%H 2 +Ar mixture under p≥l atm. The present report shows the results of detail experimental and theoretical study of this phenomenon. The experiments have been carried out on the setup with the discharge gap of about 1 cm or of much greater size. Mach-Zender interferometer and an image-converter intensifier operating as a strip or framing camera. The experiments have been carried out under the pressure 1-3 atm. They show that the stationary layers sequentially appear one after another along the direction from the cathode to the anode. Interferometry shows that there is a gas density modulation corresponding to the periodical structure of fringes. The picture of Fig.1 is a typical interferogram, and that of Fig.2 is a gas density distribution restored from it

  15. A Comparison of the Cluster-Span Threshold and the Union of Shortest Paths as Objective Thresholds of EEG Functional Connectivity Networks from Beta Activity in Alzhaimer’s Disease

    OpenAIRE

    Smith, K; Abasolo, Daniel Emilio; Escudero, J

    2016-01-01

    The Cluster-Span Threshold (CST) is a recently introduced unbiased threshold for functional connectivity networks. This binarisation technique offers a natural trade-off of sparsity and density of information by balancing the ratio of closed to open triples in the network topology. Here we present findings comparing it with the Union of Shortest Paths (USP), another recently proposed objective method. We analyse standard network metrics of binarised networks for sensitivity to clinical Alzhei...

  16. Non-covalent interactions of cadmium sulphide and gold nanoparticles with DNA

    Energy Technology Data Exchange (ETDEWEB)

    Atay, Z. [Bogazici University, Department of Chemistry (Turkey); Biver, T., E-mail: tarita@dcci.unipi.i [Universita di Pisa, Dipartimento di Chimica e Chimica Industriale (Italy); Corti, A. [Universita di Pisa, Dipartimento di Patologia Sperimentale BMIE (Italy); Eltugral, N. [Universita di Pisa, Dipartimento di Chimica e Chimica Industriale (Italy); Lorenzini, E.; Masini, M.; Paolicchi, A. [Universita di Pisa, Dipartimento di Patologia Sperimentale BMIE (Italy); Pucci, A.; Ruggeri, G.; Secco, F.; Venturini, M. [Universita di Pisa, Dipartimento di Chimica e Chimica Industriale (Italy)

    2010-08-15

    Mercaptoethanol-capped CdS nanoparticles (CdS{sub np}) and monohydroxy-(1-mercaptoundec-11-yl)tetraethylene-glycol-capped Au nanoparticles (Au{sub np}) were synthesised, characterised and their interactions with DNA were investigated. Au{sub np} are stable in different aqueous solvents, whereas CdS{sub np} do precipitate in 0.1 M NaCl and form two different cluster types in 0.1 M NaNO{sub 3}. As regards the CdS{sub np}/DNA interaction, absorbance and fluorescence titrations, ethidium bromide displacement assays and gel electrophoresis experiments indicate that a non-covalent interaction between DNA and the CdS{sub np} external surface does take place. The binding constant was evaluated to be equal to (2.2 {+-} 0.5) x 10{sup 5} M{sup -1}. On the contrary, concerning Au{sub np}, no direct interaction with DNA could be observed. Possible interaction with serum albumin was also checked, but no effects could be observed for either CdS{sub np} or Au{sub np}. Finally, short-time exposure of cultured cells to nanoparticles revealed the ability of CdS{sub np} to enter the cells and allocate both in cytosol and nucleus, thus promoting cell proliferation at low concentration (p < 0.005), while longer-time exposure resulted in a significant inhibition of cell growth, accompanied by apoptotic cell death. Au{sub np} neither enter the cells, nor do affect cell proliferation. In conclusion, our data indicate that CdS{sub np} can strongly interact with living cells and nucleic acid while no effects or interactions were observed for Au{sub np}.

  17. Oscillations of a Beam on a Non-Linear Elastic Foundation under Periodic Loads

    Directory of Open Access Journals (Sweden)

    Donald Mark Santee

    2006-01-01

    Full Text Available The complexity of the response of a beam resting on a nonlinear elastic foundation makes the design of this structural element rather challenging. Particularly because, apparently, there is no algebraic relation for its load bearing capacity as a function of the problem parameters. Such an algebraic relation would be desirable for design purposes. Our aim is to obtain this relation explicitly. Initially, a mathematical model of a flexible beam resting on a non-linear elastic foundation is presented, and its non-linear vibrations and instabilities are investigated using several numerical methods. At a second stage, a parametric study is carried out, using analytical and semi-analytical perturbation methods. So, the influence of the various physical and geometrical parameters of the mathematical model on the non-linear response of the beam is evaluated, in particular, the relation between the natural frequency and the vibration amplitude and the first period doubling and saddle-node bifurcations. These two instability phenomena are the two basic mechanisms associated with the loss of stability of the beam. Finally Melnikov's method is used to determine an algebraic expression for the boundary that separates a safe from an unsafe region in the force parameters space. It is shown that this can be used as a basis for a reliable engineering design criterion.

  18. Modelling the interaction between flooding events and economic growth

    Directory of Open Access Journals (Sweden)

    J. Grames

    2015-06-01

    Full Text Available Socio-hydrology describes the interaction between the socio-economy and water. Recent models analyze the interplay of community risk-coping culture, flooding damage and economic growth (Di Baldassarre et al., 2013; Viglione et al., 2014. These models descriptively explain the feedbacks between socio-economic development and natural disasters like floods. Contrary to these descriptive models, our approach develops an optimization model, where the intertemporal decision of an economic agent interacts with the hydrological system. In order to build this first economic growth model describing the interaction between the consumption and investment decisions of an economic agent and the occurrence of flooding events, we transform an existing descriptive stochastic model into an optimal deterministic model. The intermediate step is to formulate and simulate a descriptive deterministic model. We develop a periodic water function to approximate the former discrete stochastic time series of rainfall events. Due to the non-autonomous exogenous periodic rainfall function the long-term path of consumption and investment will be periodic.

  19. Long period seismic source characterization at Popocatépetl volcano, Mexico

    Science.gov (United States)

    Arciniega-Ceballos, Alejandra; Dawson, Phillip; Chouet, Bernard A.

    2012-01-01

    The seismicity of Popocatépetl is dominated by long-period and very-long period signals associated with hydrothermal processes and magmatic degassing. We model the source mechanism of repetitive long-period signals in the 0.4–2 s band from a 15-station broadband network by stacking long-period events with similar waveforms to improve the signal-to-noise ratio. The data are well fitted by a point source located within the summit crater ~250 m below the crater floor and ~200 m from the inferred magma conduit. The inferred source includes a volumetric component that can be modeled as resonance of a horizontal steam-filled crack and a vertical single force component. The long-period events are thought to be related to the interaction between the magmatic system and a perched hydrothermal system. Repetitive injection of fluid into the horizontal fracture and subsequent sudden discharge when a critical pressure threshold is met provides a non-destructive source process.

  20. Supportive and non-supportive interactions in families with a type 2 diabetes patient

    DEFF Research Database (Denmark)

    Bennich, Birgitte B; Røder, Michael E; Overgaard, Dorthe

    2017-01-01

    changes and diabetes self-management. The purpose of this integrative review was to summarise and assess published studies on the intra-family perspective of supportive and non-supportive interactions in families with a type 2 diabetes patient. METHODS: Included in the review were published qualitative......BACKGROUND: Type 2 diabetes and its management affect the patient and the close family potentially causing either psychological distress or increased sense of responsibility and collaboration in these families. Interactions between patient and family play an important role in maintaining lifestyle...... of reference lists. Quality assessment, data extraction and analysis were undertaken on all included studies. RESULTS: We identified five eligible research papers. Employing content analysis three categories describing interactions were refined: Impact of practical action, impact of emotional involvement...

  1. Characterising non-covalent interactions with the Cambridge Structural Database.

    Science.gov (United States)

    Lommerse, J P; Taylor, R

    1997-02-01

    This review describes how the CSD can be used to study non-covalent interactions. Several different types of information may be obtained. First, the relative frequencies of various interactions can be studied; for example, we have shown that the terminal oxygen atoms of phosphate groups accept hydrogen bonds far more often than the linkage oxygens. Secondly, information can be obtained about the geometries of nonbonded contacts; for example, hydrogen bonds to P-O groups rarely form along the extension of the P-O bond, whereas short contacts between oxygen and carbon-bound iodine show a strong preference for linear C-I ... O angles. Thirdly, the CSD can be searched for novel interactions which may be exploited in inhibitor design; for example, the I ... O contacts just mentioned, and N-H ... pi hydrogen bonds. Finally, the CSD can suggest synthetic targets for medicinal chemistry; for example, molecules containing delocalised electron deficient groups such as trimethylammonium, pyridinium, thaizolium and dinitrophenyl have a good chance of binding to an active-site tryptophan. Although the CSD contains small-molecule crystal structures, not protein-ligand complexes, there is considerable evidence that the contacts seen in the two types of structures are similar. We have illustrated this a number of times in the present review and additional evidence has been given previously by Klebe. The major advantages of the CSD are its size, diversity and experimental accuracy. For these reasons, it is a useful tool for modellers engaged in rational inhibitor design.

  2. Non-iterative method to calculate the periodical distribution of temperature in reactors with thermal regeneration

    International Nuclear Information System (INIS)

    Sanchez de Alsina, O.L.; Scaricabarozzi, R.A.

    1982-01-01

    A matrix non-iterative method to calculate the periodical distribution in reactors with thermal regeneration is presented. In case of exothermic reaction, a source term will be included. A computer code was developed to calculate the final temperature distribution in solids and in the outlet temperatures of the gases. The results obtained from ethane oxidation calculation in air, using the Dietrich kinetic data are presented. This method is more advantageous than iterative methods. (E.G.) [pt

  3. Drug interactions between non-rifamycin antibiotics and hormonal contraception: a systematic review.

    Science.gov (United States)

    Simmons, Katharine B; Haddad, Lisa B; Nanda, Kavita; Curtis, Kathryn M

    2018-01-01

    The purpose of this study was to determine whether interactions between non-rifamycin antibiotics and hormonal contraceptives result in decreased effectiveness or increased toxicity of either therapy. We searched MEDLINE, Embase, clinicaltrials.gov, and Cochrane libraries from database inception through June 2016. We included trials, cohort, case-control, and pharmacokinetic studies in any language that addressed pregnancy rates, pharmacodynamics, or pharmacokinetic outcomes when any hormonal contraceptive and non-rifamycin antibiotic were administered together vs apart. Of 7291 original records that were identified, 29 met criteria for inclusion. Two authors independently assessed study quality and risk of bias using the United States Preventive Services Task Force evidence grading system. Findings were tabulated by drug class. Study quality ranged from good to poor and addressed only oral contraceptive pills, emergency contraception pills, and the combined vaginal ring. Two studies demonstrated no difference in pregnancy rates in women who used oral contraceptives with and without non-rifamycin antibiotics. No differences in ovulation suppression or breakthrough bleeding were observed in any study that combined hormonal contraceptives with any antibiotic. No significant decreases in any progestin pharmacokinetic parameter occurred during co-administration with any antibiotic. Ethinyl estradiol area under the curve decreased when administered with dirithromycin, but no other drug. Evidence from clinical and pharmacokinetic outcomes studies does not support the existence of drug interactions between hormonal contraception and non-rifamycin antibiotics. Data are limited by low quantity and quality for some drug classes. Most women can expect no reduction in hormonal contraceptive effect with the concurrent use of non-rifamycin antibiotics. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Probing non-standard interactions at Daya Bay

    Energy Technology Data Exchange (ETDEWEB)

    Agarwalla, Sanjib Kumar; Bagchi, Partha [Institute of Physics, Sachivalaya Marg,Sainik School Post, Bhubaneswar 751005 (India); Forero, David V. [AHEP Group, Institut de Física Corpuscular - C.S.I.C./Universitat de València,Parc Cientific de Paterna, C/ Catedratico José Beltrán, 2 E-46980 Paterna (València) (Spain); Center for Neutrino Physics, Virginia Tech,Blacksburg, VA 24061 (United States); Tórtola, Mariam [AHEP Group, Institut de Física Corpuscular - C.S.I.C./Universitat de València,Parc Cientific de Paterna, C/ Catedratico José Beltrán, 2 E-46980 Paterna (València) (Spain)

    2015-07-13

    In this article we consider the presence of neutrino non-standard interactions (NSI) in the production and detection processes of reactor antineutrinos at the Daya Bay experiment. We report for the first time, the new constraints on the flavor non-universal and flavor universal charged-current NSI parameters, estimated using the currently released 621 days of Daya Bay data. New limits are placed assuming that the new physics effects are just inverse of each other in the production and detection processes. With this special choice of the NSI parameters, we observe a shift in the oscillation amplitude without distorting the L/E pattern of the oscillation probability. This shift in the depth of the oscillation dip can be caused by the NSI parameters as well as by θ{sub 13}, making it quite difficult to disentangle the NSI effects from the standard oscillations. We explore the correlations between the NSI parameters and θ{sub 13} that may lead to significant deviations in the reported value of the reactor mixing angle with the help of iso-probability surface plots. Finally, we present the limits on electron, muon/tau, and flavor universal (FU) NSI couplings with and without considering the uncertainty in the normalization of the total event rates. Assuming a perfect knowledge of the event rates normalization, we find strong upper bounds ∼ 0.1% for the electron and FU cases improving the present limits by one order of magnitude. However, for a conservative error of 5% in the total normalization, these constraints are relaxed by almost one order of magnitude.

  5. Probing non-standard interactions at Daya Bay

    International Nuclear Information System (INIS)

    Agarwalla, Sanjib Kumar; Bagchi, Partha; Forero, David V.; Tórtola, Mariam

    2015-01-01

    In this article we consider the presence of neutrino non-standard interactions (NSI) in the production and detection processes of reactor antineutrinos at the Daya Bay experiment. We report for the first time, the new constraints on the flavor non-universal and flavor universal charged-current NSI parameters, estimated using the currently released 621 days of Daya Bay data. New limits are placed assuming that the new physics effects are just inverse of each other in the production and detection processes. With this special choice of the NSI parameters, we observe a shift in the oscillation amplitude without distorting the L/E pattern of the oscillation probability. This shift in the depth of the oscillation dip can be caused by the NSI parameters as well as by θ 13 , making it quite difficult to disentangle the NSI effects from the standard oscillations. We explore the correlations between the NSI parameters and θ 13 that may lead to significant deviations in the reported value of the reactor mixing angle with the help of iso-probability surface plots. Finally, we present the limits on electron, muon/tau, and flavor universal (FU) NSI couplings with and without considering the uncertainty in the normalization of the total event rates. Assuming a perfect knowledge of the event rates normalization, we find strong upper bounds ∼ 0.1% for the electron and FU cases improving the present limits by one order of magnitude. However, for a conservative error of 5% in the total normalization, these constraints are relaxed by almost one order of magnitude.

  6. MAXI J1659-152: The shortest orbital period black-hole transient in outburst

    DEFF Research Database (Denmark)

    Kuulkers, E.; Kouveliotou, C.; Belloni, T.

    2013-01-01

    MAXI J1659−152 is a bright X-ray transient black-hole candidate binary system discovered in September 2010. We report here on MAXI, RXTE, Swift, and XMM-Newton observations during its 2010/2011 outburst. We find that during the first one and a half week of the outburst the X-ray light curves disp...

  7. Computing the non-Markovian coarse-grained interactions derived from the Mori-Zwanzig formalism in molecular systems: Application to polymer melts

    Science.gov (United States)

    Li, Zhen; Lee, Hee Sun; Darve, Eric; Karniadakis, George Em

    2017-01-01

    Memory effects are often introduced during coarse-graining of a complex dynamical system. In particular, a generalized Langevin equation (GLE) for the coarse-grained (CG) system arises in the context of Mori-Zwanzig formalism. Upon a pairwise decomposition, GLE can be reformulated into its pairwise version, i.e., non-Markovian dissipative particle dynamics (DPD). GLE models the dynamics of a single coarse particle, while DPD considers the dynamics of many interacting CG particles, with both CG systems governed by non-Markovian interactions. We compare two different methods for the practical implementation of the non-Markovian interactions in GLE and DPD systems. More specifically, a direct evaluation of the non-Markovian (NM) terms is performed in LE-NM and DPD-NM models, which requires the storage of historical information that significantly increases computational complexity. Alternatively, we use a few auxiliary variables in LE-AUX and DPD-AUX models to replace the non-Markovian dynamics with a Markovian dynamics in a higher dimensional space, leading to a much reduced memory footprint and computational cost. In our numerical benchmarks, the GLE and non-Markovian DPD models are constructed from molecular dynamics (MD) simulations of star-polymer melts. Results show that a Markovian dynamics with auxiliary variables successfully generates equivalent non-Markovian dynamics consistent with the reference MD system, while maintaining a tractable computational cost. Also, transient subdiffusion of the star-polymers observed in the MD system can be reproduced by the coarse-grained models. The non-interacting particle models, LE-NM/AUX, are computationally much cheaper than the interacting particle models, DPD-NM/AUX. However, the pairwise models with momentum conservation are more appropriate for correctly reproducing the long-time hydrodynamics characterised by an algebraic decay in the velocity autocorrelation function.

  8. The Very Short Period M Dwarf Binary SDSS J001641-000925

    Science.gov (United States)

    Davenport, James R. A.; Becker, Andrew C.; West, Andrew A.; Bochanski, John J.; Hawley, Suzanne L.; Holtzman, Jon; Gunning, Heather C.; Hilton, Eric J.; Munshi, Ferah A.; Albright, Meagan

    2013-02-01

    We present follow-up observations and analysis of the recently discovered short period low-mass eclipsing binary, SDSS J001641-000925. With an orbital period of 0.19856 days, this system has one of the shortest known periods for an M dwarf binary system. Medium-resolution spectroscopy and multi-band photometry for the system are presented. Markov Chain Monte Carlo modeling of the light curves and radial velocities yields estimated masses for the stars of M 1 = 0.54 ± 0.07 M ⊙ and M 2 = 0.34 ± 0.04 M ⊙, and radii of R 1 = 0.68 ± 0.03 R ⊙ and R 2 = 0.58 ± 0.03 R ⊙, respectively. This solution places both components above the critical Roche overfill limit, providing strong evidence that SDSS J001641-000925 is the first verified M-dwarf contact binary system. Within the follow-up spectroscopy we find signatures of non-solid body rotation velocities, which we interpret as evidence for mass transfer or loss within the system. In addition, our photometry samples the system over nine years, and we find strong evidence for period decay at the rate of \\dot{P}\\sim 8 s yr-1. Both of these signatures raise the intriguing possibility that the system is in over-contact, and actively losing angular momentum, likely through mass loss. This places SDSS J001641-000925 as not just the first M-dwarf over-contact binary, but one of the few systems of any spectral type known to be actively undergoing coalescence. Further study of SDSS J001641-000925 is ongoing to verify the nature of the system, which may prove to be a unique astrophysical laboratory. Based on observations obtained with the Apache Point Observatory 3.5 m telescope, which is owned and operated by the Astrophysical Research Consortium. This paper includes data gathered with the 6.5 m Magellan Telescopes located at Las Campanas Observatory, Chile. Support for the design and construction of the Magellan Echellette Spectrograph was received from the Observatories of the Carnegie Institution of Washington, the

  9. Reconstructing an interacting holographic polytropic gas model in a non-flat FRW universe

    International Nuclear Information System (INIS)

    Karami, K; Abdolmaleki, A

    2010-01-01

    We study the correspondence between the interacting holographic dark energy and the polytropic gas model of dark energy in a non-flat FRW universe. This correspondence allows one to reconstruct the potential and the dynamics for the scalar field of the polytropic model, which describe accelerated expansion of the universe.

  10. Reconstructing an interacting holographic polytropic gas model in a non-flat FRW universe

    Energy Technology Data Exchange (ETDEWEB)

    Karami, K; Abdolmaleki, A, E-mail: KKarami@uok.ac.i [Department of Physics, University of Kurdistan, Pasdaran Street, Sanandaj (Iran, Islamic Republic of)

    2010-05-01

    We study the correspondence between the interacting holographic dark energy and the polytropic gas model of dark energy in a non-flat FRW universe. This correspondence allows one to reconstruct the potential and the dynamics for the scalar field of the polytropic model, which describe accelerated expansion of the universe.

  11. Periodic Hamiltonian hierarchies and non-uniqueness of ...

    Indian Academy of Sciences (India)

    2016-12-02

    Dec 2, 2016 ... Ca. 1. Introduction. Through the past few decades, research in supersym- ... The subject of periodic Hamiltonians has been exam- ined for a long time ... The plan of this paper is as follows: In §2, a brief resume of SUSYQM is ...

  12. Non-quasiparticle states in a half-metallic ferromagnet with antiferromagnetic s-d(f) interaction.

    Science.gov (United States)

    Irkhin, V Yu

    2015-04-22

    Non-quasiparticle (incoherent) states which play an important role in the electronic structure of half-metallic ferromagnets (HMF) are investigated consistently in the case of antiferromagnetic s-d(f) exchange interaction. Their appropriate description in the limit of strong correlations requires a rearrangement of perturbation series in comparison with the usual Dyson equation. This consideration provides a solution of the Kondo problem in the HMF case and can be important for first-principle HMF calculations performed earlier for ferromagnetic s-d(f) interaction.

  13. Supramolecular interactions in the solid state

    Directory of Open Access Journals (Sweden)

    Giuseppe Resnati

    2015-11-01

    Full Text Available In the last few decades, supramolecular chemistry has been at the forefront of chemical research, with the aim of understanding chemistry beyond the covalent bond. Since the long-range periodicity in crystals is a product of the directionally specific short-range intermolecular interactions that are responsible for molecular assembly, analysis of crystalline solids provides a primary means to investigate intermolecular interactions and recognition phenomena. This article discusses some areas of contemporary research involving supramolecular interactions in the solid state. The topics covered are: (1 an overview and historical review of halogen bonding; (2 exploring non-ambient conditions to investigate intermolecular interactions in crystals; (3 the role of intermolecular interactions in morphotropy, being the link between isostructurality and polymorphism; (4 strategic realisation of kinetic coordination polymers by exploiting multi-interactive linker molecules. The discussion touches upon many of the prerequisites for controlled preparation and characterization of crystalline materials.

  14. Topological insulators in cold-atom gases with non-Abelian gauge fields: the role of interactions

    Energy Technology Data Exchange (ETDEWEB)

    Orth, Peter Philipp [Institut fuer Theorie der Kondensierten Materie, Karlsruher Institut fuer Technologie, 76128 Karlsruhe (Germany); Cocks, Daniel; Buchhold, Michael; Hofstetter, Walter [Institut fuer Theoretische Physik, Goethe Universitaet, 60438 Frankfurt am Main (Germany); Rachel, Stephan [Department of Physics, Yale University, New Haven, Connecticut 06520 (United States); Le Hur, Karyn [Department of Physics, Yale University, New Haven, Connecticut 06520 (United States); Center for Theoretical Physics, Ecole Polytechnique, 91128 Palaiseau Cedex (France)

    2012-07-01

    With the recent technological advance of creating (non)-Abelian gauge fields for ultracold atoms in optical lattices, it becomes possible to study the interplay of topological phases and interactions in these systems. Specifically, we consider a spinful and time-reversal invariant version of the Hofstadter problem. In addition, we allow for a hopping term which does not preserve S{sub z} spin symmetry and a staggered sublattice potential. Without interactions, the parameters can be tuned such that the system is a topological insulator. Using a combination of analytical techniques and the powerful real-space dynamical mean-field (R-DMFT) method, we discuss the effect of interactions and determine the interacting phase diagram.

  15. Non-covalent interactions between thio-caffeine derivatives and water-soluble porphyrin in ethanol-water environment

    Science.gov (United States)

    Lipke, Agnieszka; Makarska-Bialokoz, Magdalena; Sierakowska, Arleta; Jasiewicz, Beata

    2018-03-01

    To determine the binding interactions and ability to form the non-covalent systems, the association process between 5,10,15,20-tetrakis[4-(trimethylammonio)phenyl]-21H,23H-porphine tetra-p-tosylate (H2TTMePP) and a series of five structurally diverse thio-caffeine analogues has been studied in ethanol and ethanol-water solutions, analyzing its absorption and steady-state fluorescence spectra. The porphyrin fluorescence lifetimes in the systems studied were established as well. During the titration with thio-caffeine compounds the slight bathochromic effect and considerable hypochromicity of the porphyrin Soret band maximum can be noted. The fluorescence quenching effect observed for interactions in H2TTMePP - thio-caffeine derivative systems, as well as the order of binding and fluorescence quenching constants (of 105-103 mol- 1) suggest the existence of the mechanism of static quenching due to the formation of non-covalent and non-fluorescent stacking complexes. In all the systems studied the phenomenon of the fractional accessibility of the fluorophore for the quencher was observed as well. Additionally, the specific binding interactions, due to the changes in reaction environment polarity, can be observed. It was found that thio-caffeine compounds can quench the porphyrin fluorescence according to the structure of thio-substituent in caffeine molecule. The obtained results can be potentially useful from scientific, therapeutic or environmental points of view.

  16. DNA base dimers are stabilized by hydrogen-bonding interactions including non-Watson-Crick pairing near graphite surfaces.

    Science.gov (United States)

    Shankar, Akshaya; Jagota, Anand; Mittal, Jeetain

    2012-10-11

    Single- and double-stranded DNA are increasingly being paired with surfaces and nanoparticles for numerous applications, such as sensing, imaging, and drug delivery. Unlike the majority of DNA structures in bulk that are stabilized by canonical Watson-Crick pairing between Ade-Thy and Gua-Cyt, those adsorbed on surfaces are often stabilized by noncanonical base pairing, quartet formation, and base-surface stacking. Not much is known about these kinds of interactions. To build an understanding of the role of non-Watson-Crick pairing on DNA behavior near surfaces, one requires basic information on DNA base pair stacking and hydrogen-bonding interactions. All-atom molecular simulations of DNA bases in two cases--in bulk water and strongly adsorbed on a graphite surface--are conducted to study the relative strengths of stacking and hydrogen bond interactions for each of the 10 possible combinations of base pairs. The key information obtained from these simulations is the free energy as a function of distance between two bases in a pair. We find that stacking interactions exert the dominant influence on the stability of DNA base pairs in bulk water as expected. The strength of stability for these stacking interactions is found to decrease in the order Gua-Gua > Ade-Gua > Ade-Ade > Gua-Thy > Gua-Cyt > Ade-Thy > Ade-Cyt > Thy-Thy > Cyt-Thy > Cyt-Cyt. On the other hand, mutual interactions of surface-adsorbed base pairs are stabilized mostly by hydrogen-bonding interactions in the order Gua-Cyt > Ade-Gua > Ade-Thy > Ade-Ade > Cyt-Thy > Gua-Gua > Cyt-Cyt > Ade-Cyt > Thy-Thy > Gua-Thy. Interestingly, several non-Watson-Crick base pairings, which are commonly ignored, have similar stabilization free energies due to interbase hydrogen bonding as Watson-Crick pairs. This clearly highlights the importance of non-Watson-Crick base pairing in the development of secondary structures of oligonucleotides near surfaces.

  17. Introduction and application of non-stationary standardized precipitation index considering probability distribution function and return period

    Science.gov (United States)

    Park, Junehyeong; Sung, Jang Hyun; Lim, Yoon-Jin; Kang, Hyun-Suk

    2018-05-01

    The widely used meteorological drought index, the Standardized Precipitation Index (SPI), basically assumes stationarity, but recent changes in the climate have led to a need to review this hypothesis. In this study, a new non-stationary SPI that considers not only the modified probability distribution parameter but also the return period under the non-stationary process was proposed. The results were evaluated for two severe drought cases during the last 10 years in South Korea. As a result, SPIs considered that the non-stationary hypothesis underestimated the drought severity than the stationary SPI despite that these past two droughts were recognized as significantly severe droughts. It may be caused by that the variances of summer and autumn precipitation become larger over time then it can make the probability distribution wider than before. This implies that drought expressions by statistical index such as SPI can be distorted by stationary assumption and cautious approach is needed when deciding drought level considering climate changes.

  18. A Bipartite Network-based Method for Prediction of Long Non-coding RNA–protein Interactions

    Directory of Open Access Journals (Sweden)

    Mengqu Ge

    2016-02-01

    Full Text Available As one large class of non-coding RNAs (ncRNAs, long ncRNAs (lncRNAs have gained considerable attention in recent years. Mutations and dysfunction of lncRNAs have been implicated in human disorders. Many lncRNAs exert their effects through interactions with the corresponding RNA-binding proteins. Several computational approaches have been developed, but only few are able to perform the prediction of these interactions from a network-based point of view. Here, we introduce a computational method named lncRNA–protein bipartite network inference (LPBNI. LPBNI aims to identify potential lncRNA–interacting proteins, by making full use of the known lncRNA–protein interactions. Leave-one-out cross validation (LOOCV test shows that LPBNI significantly outperforms other network-based methods, including random walk (RWR and protein-based collaborative filtering (ProCF. Furthermore, a case study was performed to demonstrate the performance of LPBNI using real data in predicting potential lncRNA–interacting proteins.

  19. Interactions of seedborne bacterial pathogens with host and non-host plants in relation to seed infestation and seedling transmission.

    Science.gov (United States)

    Dutta, Bhabesh; Gitaitis, Ronald; Smith, Samuel; Langston, David

    2014-01-01

    The ability of seed-borne bacterial pathogens (Acidovorax citrulli, Clavibacter michiganensis subsp. michiganensis, Pseudomonas syringae pv. tomato, Xanthomonas euvesicatoria, and Pseudomonas syringae pv. glycinea) to infest seeds of host and non-host plants (watermelon, tomato, pepper, and soybean) and subsequent pathogen transmission to seedlings was investigated. A non-pathogenic, pigmented strain of Serratia marcescens was also included to assess a null-interacting situation with the same plant species. Flowers of host and non-host plants were inoculated with 1 × 10(6) colony forming units (CFUs)/flower for each bacterial species and allowed to develop into fruits or umbels (in case of onion). Seeds harvested from each host/non-host bacterial species combination were assayed for respective bacteria by plating on semi-selective media. Additionally, seedlots for each host/non-host bacterial species combination were also assayed for pathogen transmission by seedling grow-out (SGO) assays under greenhouse conditions. The mean percentage of seedlots infested with compatible and incompatible pathogens was 31.7 and 30.9% (by plating), respectively and they were not significantly different (P = 0.67). The percentage of seedlots infested with null-interacting bacterial species was 16.8% (by plating) and it was significantly lower than the infested lots generated with compatible and incompatible bacterial pathogens (P = 0.03). None of the seedlots with incompatible/null-interacting bacteria developed symptoms on seedlings; however, when seedlings were assayed for epiphytic bacterial presence, 19.5 and 9.4% of the lots were positive, respectively. These results indicate that the seeds of non-host plants can become infested with incompatible and null-interacting bacterial species through flower colonization and they can be transmitted via epiphytic colonization of seedlings. In addition, it was also observed that flowers and seeds of non-host plants can be colonized by

  20. Interactions of seedborne bacterial pathogens with host and non-host plants in relation to seed infestation and seedling transmission.

    Directory of Open Access Journals (Sweden)

    Bhabesh Dutta

    Full Text Available The ability of seed-borne bacterial pathogens (Acidovorax citrulli, Clavibacter michiganensis subsp. michiganensis, Pseudomonas syringae pv. tomato, Xanthomonas euvesicatoria, and Pseudomonas syringae pv. glycinea to infest seeds of host and non-host plants (watermelon, tomato, pepper, and soybean and subsequent pathogen transmission to seedlings was investigated. A non-pathogenic, pigmented strain of Serratia marcescens was also included to assess a null-interacting situation with the same plant species. Flowers of host and non-host plants were inoculated with 1 × 10(6 colony forming units (CFUs/flower for each bacterial species and allowed to develop into fruits or umbels (in case of onion. Seeds harvested from each host/non-host bacterial species combination were assayed for respective bacteria by plating on semi-selective media. Additionally, seedlots for each host/non-host bacterial species combination were also assayed for pathogen transmission by seedling grow-out (SGO assays under greenhouse conditions. The mean percentage of seedlots infested with compatible and incompatible pathogens was 31.7 and 30.9% (by plating, respectively and they were not significantly different (P = 0.67. The percentage of seedlots infested with null-interacting bacterial species was 16.8% (by plating and it was significantly lower than the infested lots generated with compatible and incompatible bacterial pathogens (P = 0.03. None of the seedlots with incompatible/null-interacting bacteria developed symptoms on seedlings; however, when seedlings were assayed for epiphytic bacterial presence, 19.5 and 9.4% of the lots were positive, respectively. These results indicate that the seeds of non-host plants can become infested with incompatible and null-interacting bacterial species through flower colonization and they can be transmitted via epiphytic colonization of seedlings. In addition, it was also observed that flowers and seeds of non-host plants can be

  1. The spectral analysis of cyclo-non-stationary signals

    Science.gov (United States)

    Abboud, D.; Baudin, S.; Antoni, J.; Rémond, D.; Eltabach, M.; Sauvage, O.

    2016-06-01

    Condition monitoring of rotating machines in speed-varying conditions remains a challenging task and an active field of research. Specifically, the produced vibrations belong to a particular class of non-stationary signals called cyclo-non-stationary: although highly non-stationary, they contain hidden periodicities related to the shaft angle; the phenomenon of long term modulations is what makes them different from cyclostationary signals which are encountered under constant speed regimes. In this paper, it is shown that the optimal way of describing cyclo-non-stationary signals is jointly in the time and the angular domains. While the first domain describes the waveform characteristics related to the system dynamics, the second one reveals existing periodicities linked to the system kinematics. Therefore, a specific class of signals - coined angle-time cyclostationary is considered, expressing the angle-time interaction. Accordingly, the related spectral representations, the order-frequency spectral correlation and coherence functions are proposed and their efficiency is demonstrated on two industrial cases.

  2. Cold-Fluid Equilibrium of a Large-Aspect-Ratio Ellipse-Shaped Charged-Particle Beam in a Non-Axisymmetric Periodic Permanent Magnet Focusing Field

    CERN Document Server

    Zhou, Jing; Chen Chi Ping

    2005-01-01

    A new class of equilibrium is discovered for a large-aspect-ratio ellipse-shaped charged-particle beam in a non-axisymmetric periodic permanent magnet focusing field. A paraxial cold-fluid model is employed to derive the equilibrium flow properties and generalized envelope equations with negligibly small emittance. A periodic beam equilibrium solution is obtained numerically from the generalized envelope equations. It is shown that the beam edges are well confined in both transverse directions, and that the equilibrium beam exhibits a small-angle periodic wobble as it propagates. A two-dimensional particle-in-cell (PIC) code, PFB2D, is used to verify the theoretical predictions in the paraxial limit, and to establish validity under non-paraxial situations and the influence of the conductor walls of the beam tunnel.

  3. On the Organization of Parallel Operation of Some Algorithms for Finding the Shortest Path on a Graph on a Computer System with Multiple Instruction Stream and Single Data Stream

    Directory of Open Access Journals (Sweden)

    V. E. Podol'skii

    2015-01-01

    Full Text Available The paper considers the implementing Bellman-Ford and Lee algorithms to find the shortest graph path on a computer system with multiple instruction stream and single data stream (MISD. The MISD computer is a computer that executes commands of arithmetic-logical processing (on the CPU and commands of structures processing (on the structures processor in parallel on a single data stream. Transformation of sequential programs into the MISD programs is a labor intensity process because it requires a stream of the arithmetic-logical processing to be manually separated from that of the structures processing. Algorithms based on the processing of data structures (e.g., algorithms on graphs show high performance on a MISD computer. Bellman-Ford and Lee algorithms for finding the shortest path on a graph are representatives of these algorithms. They are applied to robotics for automatic planning of the robot movement in-situ. Modification of Bellman-Ford and Lee algorithms for finding the shortest graph path in coprocessor MISD mode and the parallel MISD modification of these algorithms were first obtained in this article. Thus, this article continues a series of studies on the transformation of sequential algorithms into MISD ones (Dijkstra and Ford-Fulkerson 's algorithms and has a pronouncedly applied nature. The article also presents the analysis results of Bellman-Ford and Lee algorithms in MISD mode. The paper formulates the basic trends of a technique for parallelization of algorithms into arithmetic-logical processing stream and structures processing stream. Among the key areas for future research, development of the mathematical approach to provide a subsequently formalized and automated process of parallelizing sequential algorithms between the CPU and structures processor is highlighted. Among the mathematical models that can be used in future studies there are graph models of algorithms (e.g., dependency graph of a program. Due to the high

  4. Non-interacting surface solvation and dynamics in protein-protein interactions

    NARCIS (Netherlands)

    Visscher, Koen M.; Kastritis, Panagiotis L.|info:eu-repo/dai/nl/315886668; Bonvin, Alexandre M J J|info:eu-repo/dai/nl/113691238

    2015-01-01

    Protein-protein interactions control a plethora of cellular processes, including cell proliferation, differentiation, apoptosis, and signal transduction. Understanding how and why proteins interact will inevitably lead to novel structure-based drug design methods, as well as design of de novo

  5. Thermal solid-state Z/E isomerization of 2-alkylidene-4-oxothiazolidines: effects of non-covalent interactions

    Directory of Open Access Journals (Sweden)

    ZDRAVKO DŽAMBASKI

    2011-03-01

    Full Text Available Configurational isomerization of stereo-defined 5-substituted and unsubstituted 2-alkylidene-4-oxothiazolidines (1 in the solid state, giving the Z/E mixtures in various ratios, was investigated by 1H-NMR spectroscopy, X-ray powder crystallography and differential scanning calorimetry (DSC. The Z/E composition can be rationalized in terms of non-covalent interactions, involving intermolecular and intramolecular hydrogen bonding and directional non-bonded 1,5-type S×××O interactions. X-Ray powder crystallography, using selected crystalline (Z-4-oxothiazolidine substrates, revealed transformation to the amorphous state during the irreversible Z®E process. A correlation between previous results on the Z/E isomerization in solution and now in the solid state was established.

  6. Comparing physically abusive, neglectful, and non-maltreating parents during interactions with their children: a meta-analysis of observational studies.

    Science.gov (United States)

    Wilson, Steven R; Rack, Jessica J; Shi, Xiaowei; Norris, Alda M

    2008-09-01

    To clarify the nature and extent of differences in the ways that physically abusive, neglectful, and non-maltreating parents communicate during interactions with their children. A meta-analysis was conducted of 33 observational studies comparing parent-child interactions in families where parents have a documented history of physical abuse or neglect vs. where parents have no history of child maltreatment. Parental behaviors were grouped into three clusters (positivity, aversiveness, and involvement) for comparison across studies. When comparing maltreating (physically abusive or neglectful) vs. non-maltreating parents, mean weighted effect sizes for the three behavioral clusters range from d=.46 to .62. Physically abusive parents are distinguished from non-maltreating parents more so than neglectful parents in terms of aversive behavior, whereas the reverse is true for involvement. Publication date, parent and child age, and task structure moderate the magnitude, though not direction, of differences. Parents with a documented history of child physical abuse or child neglect also are distinguished from non-maltreating parents by the levels of aversiveness, positivity, and involvement they display during interactions that constitute the parent-child relationship. Researchers and practitioners need to carefully consider sample size, length and setting of observation, and interaction tasks when using observational methods.

  7. The study on the non-linear soil structure interaction for nuclear power plants

    International Nuclear Information System (INIS)

    Tetsuya Hagiwara; Yoshio Kitada

    2005-01-01

    1. Introduction: JNES is planning a new project to study non-linear soil-structure interaction (SSI) effect under large earthquake ground motions equivalent to and/or over a design earthquake ground motion of S2(The extreme design earthquake). Concerning the SSI test, it is pointed out that handling of the scale effect of the specimen together with the surrounding soil on the earthquake response evaluation of the actual structure is essential issue for the scaled model test. Thus, for the test, the largest specimen possible and the biggest input motion possible are necessary. Taking into account the above issues, new test methodology, which utilizes artificial earthquake ground motion, is considered desirable if it can be performed at a realistic cost. Under this motivation, we have studied the test methodology which applying blasting power as for a big earthquake ground motion. The information from a coal mine company in the U.S.A. indicates that the works performed in the surface coal mine to blast a rock covering a coal layer generates a big artificial ground motion, which is similar to earthquake ground motion. Application of this artificial earthquake ground motion for the SSI test is considered very promising because the blasting work is carried out periodically for mining coal so that we can apply artificial motions generated by the work if we construct a building model at a closed point to the blasting work area. The major purposes of the test will be to understand (a) basic earthquake response characteristics of a Nuclear Power Plant (NPP) reactor building when a large earthquake strikes the NPP site and (b) nonlinear characteristics of SSI phenomenon during a big earthquake. In the paper, we introduce the test method and basic characteristics of measured artificial ground motions generated by the blasting works on an actual site. 2. Conclusion: It was confirmed that the artificial ground motions generated by blasting works have enough acceleration level

  8. The Ratio Evolution Analysis of the Non-Performing Loans Obtained by the Credit Institutions in Romania during the Period 2007-2015

    Directory of Open Access Journals (Sweden)

    Mirela Catalina Turkes

    2015-06-01

    Full Text Available This article analyses the ratio evolution of the non-performing loans obtained by the privately, Romanian and foreign-owned credit institutions, in Romania, during the period December 2007 - June 2015, depending on the change of the legislation regarding the reporting methodology for the purpose of the institutions surveillance according to the prudential regulations of BNR (National Bank of Romania and EU Regulation. The results of this analysis highlighted the fact that the non-performing loans ratio went through a spectacular increase during the period 2007-2013, reaching 21.87% following the promotion of a strategic plan based on the recovery of the debts by restructuring actions, rescheduling or enforcement. In 2014, the non-performing loans ratio decreases to 15.33% following the modification of the debt recovery strategic plan by taking them out from the balance sheet and by their integral provisioning.

  9. Inferring probabilistic stellar rotation periods using Gaussian processes

    Science.gov (United States)

    Angus, Ruth; Morton, Timothy; Aigrain, Suzanne; Foreman-Mackey, Daniel; Rajpaul, Vinesh

    2018-02-01

    Variability in the light curves of spotted, rotating stars is often non-sinusoidal and quasi-periodic - spots move on the stellar surface and have finite lifetimes, causing stellar flux variations to slowly shift in phase. A strictly periodic sinusoid therefore cannot accurately model a rotationally modulated stellar light curve. Physical models of stellar surfaces have many drawbacks preventing effective inference, such as highly degenerate or high-dimensional parameter spaces. In this work, we test an appropriate effective model: a Gaussian Process with a quasi-periodic covariance kernel function. This highly flexible model allows sampling of the posterior probability density function of the periodic parameter, marginalizing over the other kernel hyperparameters using a Markov Chain Monte Carlo approach. To test the effectiveness of this method, we infer rotation periods from 333 simulated stellar light curves, demonstrating that the Gaussian process method produces periods that are more accurate than both a sine-fitting periodogram and an autocorrelation function method. We also demonstrate that it works well on real data, by inferring rotation periods for 275 Kepler stars with previously measured periods. We provide a table of rotation periods for these and many more, altogether 1102 Kepler objects of interest, and their posterior probability density function samples. Because this method delivers posterior probability density functions, it will enable hierarchical studies involving stellar rotation, particularly those involving population modelling, such as inferring stellar ages, obliquities in exoplanet systems, or characterizing star-planet interactions. The code used to implement this method is available online.

  10. The effect of non-sphericity on mass and anisotropy measurements in dSph galaxies with Schwarzschild method

    Science.gov (United States)

    Kowalczyk, Klaudia; Łokas, Ewa L.; Valluri, Monica

    2018-05-01

    In our previous work we confirmed the reliability of the spherically symmetric Schwarzschild orbit-superposition method to recover the mass and velocity anisotropy profiles of spherical dwarf galaxies. Here, we investigate the effect of its application to intrinsically non-spherical objects. For this purpose we use a model of a dwarf spheroidal galaxy formed in a numerical simulation of a major merger of two discy dwarfs. The shape of the stellar component of the merger remnant is axisymmetric and prolate which allows us to identify and measure the bias caused by observing the spheroidal galaxy along different directions, especially the longest and shortest principal axis. The modelling is based on mock data generated from the remnant that are observationally available for dwarfs: projected positions and line-of-sight velocities of the stars. In order to obtain a reliable tool while keeping the number of parameters low we parametrize the total mass distribution as a radius-dependent mass-to-light ratio with just two free parameters we aim to constrain. Our study shows that if the total density profile is known, the true, radially increasing anisotropy profile can be well recovered for the observations along the longest axis whereas the data along the shortest axis lead to the inference of an incorrect, isotropic model. On the other hand, if the density profile is derived from the method as well, the anisotropy is always underestimated but the total mass profile is well recovered for the data along the shortest axis whereas for the longest axis the mass content is overestimated.

  11. Species traits and their non-additive interactions control the water economy of bryophyte cushions.

    NARCIS (Netherlands)

    Michel, P.; Lee, W.G.; During, H.J.; Cornelissen, J.H.C.; van der Putten, W.H.

    2012-01-01

    1. Ecological processes in mixed-species assemblages are not always an additive function of those in monocultures. In areas with high ground cover of bryophytes, renowned for their considerable water retention capacity, non-additive interactions in mixed-species cushions could play a key role in the

  12. SPECTROSCOPIC ORBITAL PERIODS FOR 29 CATACLYSMIC VARIABLES FROM THE SLOAN DIGITAL SKY SURVEY

    Energy Technology Data Exchange (ETDEWEB)

    Thorstensen, John R.; Taylor, Cynthia J.; Peters, Christopher S.; Skinner, Julie N. [Department of Physics and Astronomy 6127 Wilder Laboratory, Dartmouth College Hanover, NH 03755-3528 (United States); Southworth, John [Astrophysics Group Keele University Staffordshire ST5 5BG (United Kingdom); Gänsicke, Boris T. [Department of Physics University of Warwick Coventry CV4 7AL (United Kingdom)

    2015-04-15

    We report follow-up spectroscopy of 29 cataclysmic variables from the Sloan Digital Sky Survey (SDSS), 22 of which were discovered by SDSS and seven of which are previously known systems that were recovered in SDSS. The periods for 16 of these objects were included in the tabulation by Gänsicke et al. While most of the systems have periods less than 2 hr, only one has a period in the 80–86 minutes “spike” found by Gänsicke et al., and 11 have periods longer than 3 hr, indicating that the present sample is skewed toward longer-period, higher-luminosity objects. Seven of the objects have spectra resembling dwarf novae, but have apparently never been observed in outburst, suggesting that many cataclysmics with relatively low variability amplitude remain to be discovered. Some of the objects are notable. SDSS J07568+0858 and SDSS J08129+1911 were previously known to have deep eclipses; in addition to spectroscopy, we use archival data from the Catalina Real Time Transient Survey to refine their periods. We give a parallax-based distance of 195 (+54, −39) pc for LV Cnc (SDSS J09197+0857), which at P{sub orb} = 81 m has the shortest orbital period in our sample. SDSS J08091+3814 shows both the spectroscopic phase offset and phase-dependent absorption found in SW Sextantis stars. The average spectra of SDSS J08055+0720 and SDSS J16191+1351 show contributions from K-type secondaries, and SDSS J080440+0239 shows a contribution from an early M star. We use these to constrain the distances. SDSS J09459+2922 has characteristics typical of a magnetic system. SDSS11324+6249 may be a novalike variable, and if so, its orbital period (99 minutes) is unusually short for that subclass.

  13. Influence of magnetoelastic coupling on the phase transitions in two-dimensional non-Heisenberg magnetics with biquadratic interaction

    International Nuclear Information System (INIS)

    Fridman, Yu.A.; Klevets, Ph.N.; Kozhemyako, O.V.

    2003-01-01

    Influence of magnetoelastic (ME) interaction on the phase transitions in two-dimensional non-Heisenberg ferromagnets is investigated. It is shown that if the constant of Heisenberg exchange interaction is large, the ferromagnetic phase is implemented in a system. When the value of biquadratic exchange interaction increases there is a phase transition to the quadrupolar phase characterized by the tensor order parameters. Thus, ME interaction plays an essential role, not only stabilizing the long-range magnetic order in the system, but also determining the order of the phase transition

  14. Inter- and intramolecular non-covalent interactions in 1-methylimidazole-2-carbaldehyde complexes of copper, silver, and gold

    Science.gov (United States)

    Koskinen, Laura; Jääskeläinen, Sirpa; Hirva, Pipsa; Haukka, Matti

    2014-09-01

    Three new imidazole compounds, [CuBr2(mimc)2] (1), [Ag(mimc)2][CF3SO3] (2), and [AuCl3(mimc)] (3) (mimc = 1-methylimidazole-2-carbaldehyde), have been synthesized, structurally characterized, and further analyzed using the QTAIM analysis. The compounds exhibit self-assembled 3D networks arising from intermolecular non-covalent interactions such as metallophilic interactions, metal-π contacts, halogens-halogen interactions, and hydrogen bonds. These weak interactions have a strong impact on the coordination sphere of the metal atoms and on the packing of compounds 1, 2, and 3.

  15. Filtered Rayleigh scattering mixing measurements of merging and non-merging streamwise vortex interactions in supersonic flow

    Science.gov (United States)

    Ground, Cody R.; Gopal, Vijay; Maddalena, Luca

    2018-04-01

    By introducing large-scale streamwise vortices into a supersonic flow it is possible to enhance the rate of mixing between two fluid streams. However, increased vorticity content alone does not explicitly serve as a predictor of mixing enhancement. Additional factors, particularly the mutual interactions occurring between neighboring vortical structures, affect the underlying fundamental physics that influence the rate at which the fluids mix. As part of a larger systematic study on supersonic streamwise vortex interactions, this work experimentally quantifies the average rate of mixing of helium and air in the presence of two separate modes of vortex interaction, the merging and non-merging of a pair of co-rotating vortices. In these experiments vortex-generating expansion ramps are placed on a strut injector. The freestream Mach number is set at 2.5 and helium is injected as a passive scalar. Average injectant mole fractions at selected flow planes downstream of the injector are measured utilizing the filtered Rayleigh scattering technique. The filtered Rayleigh scattering measurements reveal that, in the domain surveyed, the merging vortex interaction strongly displaces the plume from its initial horizontal orientation while the non-merging vortex interaction more rapidly mixes the helium and air. The results of the current experiments are consistent with associated knowledge derived from previous analyses of the two studied configurations which have included the detailed experimental characterization of entrainment, turbulent kinetic energy, and vorticity of both modes of vortex interaction.

  16. A novel environmental exposure index and its interaction with familial susceptibility on oral cancer in non-smokers and non-drinkers: a case-control study.

    Science.gov (United States)

    Yan, Lingjun; Chen, Fa; He, Baochang; Liu, Fengqiong; Liu, Fangping; Huang, Jiangfeng; Wu, Junfeng; Lin, Lisong; Qiu, Yu; Cai, Lin

    2017-04-01

    The objective of this study was to explore the collective effect of environmental factors and its interaction with familial susceptibility on oral cancer among non-smokers and non-drinkers (NSND). A hospital-based case-control study, including 319 oral cancer patients and 994 frequency-matched controls, was conducted in Fujian, China. We raised a weighed environmental exposure index according to nine significant environmental factors obtained from multivariable logistic regression model. And then, the index was classified into three categories according to the tertiles of controls (2.43). Multiplicative and additive interactions were evaluated between environmental exposure index and family cancer history. Our results showed that environmental exposure index was associated with an increased risk of oral cancer especially for those with family cancer history. Compared to subjects with low environmental exposure index and without family cancer history, those with high index and family cancer history showed the highest magnitude of OR in oral cancer risk (OR 10.40, 95% CI 5.46-19.80). Moreover, there was a multiplicative interaction between environmental exposure index and family cancer history for the risk of oral cancer (P oral cancer among NSND and may interact with family cancer history. Further studies are warranted to explore the underlying mechanisms.

  17. On the interaction of non-ionizing radiation with people. Technical report

    Energy Technology Data Exchange (ETDEWEB)

    Ruderman, M.A.; MacDonald, G.J.

    1980-03-01

    This report examines the physical basis for many of the thermal and non-thermal interactions between microwaves and the human body. Although a microwave beam incident on the human body dissipates, on the average, about the same amount of heat as does normal metabolism, it can actually dissipate considerably more heat in certain local regions of the body because of strong beam focusing effects (e.g., within the brain), flow of induced currents through small, constricted areas of the body (e.g., ankle, neck) and differences in electrical properties among body tissues. Since relatively large heat dissipation can occur on a local level, it would appear more rational to determine a maximum permissive radiation exposure in terms of maximum allowed dissipation in a specific sensitive part of the body rather than, as is presently done, in terms of external beam intensity (the present U.S. standard is 10 milliwatts/sq cm). For non-thermal processes, no special biological process or structure has been identified as likely to be especially sensitive to microwave fields or frequencies. The experimental results designed to explore the non-thermal effect of microwaves were studied. The results of all experiments purporting to demonstrate a significant non-thermal biological effect have been disputed; in fact, very few experiments in the entire field have ever been replicated -- a situation which should be rectified.

  18. Long-period Intensity Pulsations in Coronal Loops Explained by Thermal Non-equilibrium Cycles

    Energy Technology Data Exchange (ETDEWEB)

    Froment, C.; Auchère, F.; Bocchialini, K.; Buchlin, E.; Solomon, J. [Institut d’Astrophysique Spatiale, CNRS, Univ. Paris-Sud, Université Paris-Saclay, Bât. 121, F-91405 Orsay cedex (France); Aulanier, G. [LESIA, Observatoire de Paris, PSL Research University, CNRS, Sorbonne Universités, UPMC Univ. Paris 06, Univ. Paris Diderot, Sorbonne Paris Cité, 5 place Jules Janssen, F-92195 Meudon (France); Mikić, Z., E-mail: clara.froment@astro.uio.no [Predictive Science, Inc., San Diego, CA 92121 (United States)

    2017-02-01

    In solar coronal loops, thermal non-equilibrium (TNE) is a phenomenon that can occur when the heating is both highly stratified and quasi-constant. Unambiguous observational identification of TNE would thus permit us to strongly constrain heating scenarios. While TNE is currently the standard interpretation of coronal rain, the long-term periodic evolution predicted by simulations has never been observed. However, the detection of long-period intensity pulsations (periods of several hours) has been recently reported with the Solar and Heliospheric Observatory /EIT, and this phenomenon appears to be very common in loops. Moreover, the three intensity-pulsation events that we recently studied with the Solar Dynamics Observatory /Atmospheric Imaging Assembly (AIA) show strong evidence for TNE in warm loops. In this paper, a realistic loop geometry from linear force-free field (LFFF) extrapolations is used as input to 1D hydrodynamic simulations. Our simulations show that, for the present loop geometry, the heating has to be asymmetrical to produce TNE. We analyze in detail one particular simulation that reproduces the average thermal behavior of one of the pulsating loop bundle observed with AIA. We compare the properties of this simulation with those deduced from the observations. The magnetic topology of the LFFF extrapolations points to the presence of sites of preferred reconnection at one footpoint, supporting the presence of asymmetric heating. In addition, we can reproduce the temporal large-scale intensity properties of the pulsating loops. This simulation further strengthens the interpretation of the observed pulsations as signatures of TNE. This consequently provides important information on the heating localization and timescale for these loops.

  19. Model-free inference of direct network interactions from nonlinear collective dynamics.

    Science.gov (United States)

    Casadiego, Jose; Nitzan, Mor; Hallerberg, Sarah; Timme, Marc

    2017-12-19

    The topology of interactions in network dynamical systems fundamentally underlies their function. Accelerating technological progress creates massively available data about collective nonlinear dynamics in physical, biological, and technological systems. Detecting direct interaction patterns from those dynamics still constitutes a major open problem. In particular, current nonlinear dynamics approaches mostly require to know a priori a model of the (often high dimensional) system dynamics. Here we develop a model-independent framework for inferring direct interactions solely from recording the nonlinear collective dynamics generated. Introducing an explicit dependency matrix in combination with a block-orthogonal regression algorithm, the approach works reliably across many dynamical regimes, including transient dynamics toward steady states, periodic and non-periodic dynamics, and chaos. Together with its capabilities to reveal network (two point) as well as hypernetwork (e.g., three point) interactions, this framework may thus open up nonlinear dynamics options of inferring direct interaction patterns across systems where no model is known.

  20. A brief status of non-standard neutrino interactions

    International Nuclear Information System (INIS)

    Ohlsson, Tommy

    2013-01-01

    In this plenary talk, we review the status of non-standard neutrino interactions (NSIs). First, we give a brief introduction to neutrino flavor transitions with NSIs based on the standard paradigm of neutrino oscillations. Then, we discuss alternative scenarios for neutrino flavor transitions such as neutrino decoherence, neutrino decay, and NSIs. Second, we investigate NSIs with three neutrino flavors. In general, we introduce production and detection NSIs, including the so-called zero-distance effect, and matter NSIs. In addition, we study mappings and approximate formulas for NSIs. Third, we present a brief account of theoretical models for NSIs. Fourth and most important, we investigate in detail the phenomenology of NSIs based on different types of data from neutrino experiments. Fifth, we give some phenomenological bounds on both matter and production/detection NSIs as well as we present sensitivity and discovery reach of NSIs at future experiments. Finally, we present a summary and state our conclusions

  1. Interaction of dependent and non-dependent regions of the acutely injured lung during a stepwise recruitment manoeuvre

    International Nuclear Information System (INIS)

    Gómez-Laberge, Camille; Rettig, Jordan S; Arnold, John H; Wolf, Gerhard K; Smallwood, Craig D; Boyd, Theonia K

    2013-01-01

    The benefit of treating acute lung injury with recruitment manoeuvres is controversial. An impediment to settling this debate is the difficulty in visualizing how distinct lung regions respond to the manoeuvre. Here, regional lung mechanics were studied by electrical impedance tomography (EIT) during a stepwise recruitment manoeuvre in a porcine model with acute lung injury. The following interaction between dependent and non-dependent regions consistently occurred: atelectasis in the most dependent region was reversed only after the non-dependent region became overdistended. EIT estimates of overdistension and atelectasis were validated by histological examination of lung tissue, confirming that the dependent region was primarily atelectatic and the non-dependent region was primarily overdistended. The pulmonary pressure–volume equation, originally designed for modelling measurements at the airway opening, was adapted for EIT-based regional estimates of overdistension and atelectasis. The adaptation accurately modelled the regional EIT data from dependent and non-dependent regions (R 2 > 0.93, P < 0.0001) and predicted their interaction during recruitment. In conclusion, EIT imaging of regional lung mechanics reveals that overdistension in the non-dependent region precedes atelectasis reversal in the dependent region during a stepwise recruitment manoeuvre. (paper)

  2. Non-equilibrium work distribution for interacting colloidal particles under friction

    International Nuclear Information System (INIS)

    Gomez-Solano, Juan Ruben; July, Christoph; Mehl, Jakob; Bechinger, Clemens

    2015-01-01

    We experimentally investigate the non-equilibrium steady-state distribution of the work done by an external force on a mesoscopic system with many coupled degrees of freedom: a colloidal crystal mechanically driven across a commensurate periodic light field. Since this system mimics the spatiotemporal dynamics of a crystalline surface moving on a corrugated substrate, our results show general properties of the work distribution for atomically flat surfaces undergoing friction. We address the role of several parameters which can influence the shape of the work distribution, e.g. the number of particles used to locally probe the properties of the system and the time interval to measure the work. We find that, when tuning the control parameters to induce particle depinning from the substrate, there is an abrupt change of the shape of the work distribution. While in the completely static and sliding friction regimes the work distribution is Gaussian, non-Gaussian tails show up due to the spatiotemporal heterogeneity of the particle dynamics during the transition between these two regimes. (paper)

  3. RADIO FLARING FROM THE T6 DWARF WISEPC J112254.73+255021.5 WITH A POSSIBLE ULTRA-SHORT PERIODICITY

    Energy Technology Data Exchange (ETDEWEB)

    Route, Matthew; Wolszczan, Alexander, E-mail: mroute@purdue.edu, E-mail: alex@astro.psu.edu [Department of Astronomy and Astrophysics, the Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States)

    2016-04-20

    We present new results from a continuing 5 GHz search for flaring radio emission from a sample of L and T brown dwarfs, conducted with the 305 m Arecibo radio telescope. In addition to the previously reported flaring from the T6.5 dwarf 2MASS J10475385+212423, we have detected and confirmed circularly polarized flares from another T6 dwarf, WISEPC J112254.73+255021.5. Although the flares are sporadic, they appear to occur at a stable period of 0.288 hr. Given the current constraints, periods equal to its second and third subharmonic cannot be ruled out. The stability of this period over the eight-month timespan of observations indicates that, if real, it likely reflects the star’s rapid rotation. If confirmed, any of the three inferred periodicities would be much shorter than the shortest, 1.41 hr, rotation period of a brown dwarf measured so far. This finding would place a new observational constraint on the angular momentum evolution and rotational stability of substellar objects. The detection of radio emission from the sixth ∼1000 K dwarf further demonstrates that the coolest brown dwarfs and, possibly, young giant planets, can be efficiently investigated using radio observations at centimeter wavelengths as a tool.

  4. Non-radial oscillations of rotating stars and their relevance to the short-period oscillations of cataclysmic variables

    International Nuclear Information System (INIS)

    Papaloizou, J.; Pringle, J.E.

    1978-01-01

    The usual hypothesis, that the short-period coherent oscillations seen in cataclysmic variables are attributable to g modes in a slowly rotating white dwarf, is considered. It is shown that this hypothesis is untenable for three main reasons: (i) the observed periods are too short for reasonable white dwarf models, (ii) the observed variability of the oscillations is too rapid and (iii) the expected rotation of the white dwarf, due to accretion, invalidates the slow rotation assumption on which standard g-mode theory is based. The low-frequency spectrum of a rotating pulsating star is investigated taking the effects of rotation fully into account. In this case there are two sets of low-frequency modes, the g modes, and modes similar to Rossby waves in the Earth's atmosphere and oceans, which are designated r modes. Typical periods for such modes are 1/m times the rotation period of the white dwarfs outer layers (m is the aximuthal wavenumber). It is concluded that non-radial oscillations of rotating white dwarfs can account for the properties of the oscillations seen in dwarf novae. Application of these results to other systems is also discussed. (author)

  5. Reconstructing interacting entropy-corrected holographic scalar field models of dark energy in the non-flat universe

    Energy Technology Data Exchange (ETDEWEB)

    Karami, K; Khaledian, M S [Department of Physics, University of Kurdistan, Pasdaran Street, Sanandaj (Iran, Islamic Republic of); Jamil, Mubasher, E-mail: KKarami@uok.ac.ir, E-mail: MS.Khaledian@uok.ac.ir, E-mail: mjamil@camp.nust.edu.pk [Center for Advanced Mathematics and Physics (CAMP), National University of Sciences and Technology (NUST), Islamabad (Pakistan)

    2011-02-15

    Here we consider the entropy-corrected version of the holographic dark energy (DE) model in the non-flat universe. We obtain the equation of state parameter in the presence of interaction between DE and dark matter. Moreover, we reconstruct the potential and the dynamics of the quintessence, tachyon, K-essence and dilaton scalar field models according to the evolutionary behavior of the interacting entropy-corrected holographic DE model.

  6. Non-covalent interactions of the carcinogen (+)-anti-BPDE with exon 1 of the human K-ras proto-oncogene

    Science.gov (United States)

    Rodriguez, Jorge H.; Deligkaris, Christos

    2013-03-01

    Investigating the complementary, but different, effects of physical (non-covalent) and chemical (covalent) mutagen-DNA and carcinogen-DNA interactions is important for understanding possible mechanisms of development and prevention of mutagenesis and carcinogenesis. A highly mutagenic and carcinogenic metabolite of the polycyclic aromatic hydrocarbon benzo[ α]pyrene, namely (+)-anti-BPDE, is known to undergo both physical and chemical complexation with DNA. The major covalent adduct, a promutagenic, is known to be an external (+)-trans-anti-BPDE-N2-dGuanosine configuration whose origins are not fully understood. Thus, it is desirable to study the mechanisms of external non-covalent BPDE-DNA binding and their possible relationships to external covalent trans adduct formation. We present a detailed codon-by-codon computational study of the non-covalent interactions of (+)-anti-BPDE with DNA which explains and correctly predicts preferential (+)-anti-BPDE binding at minor groove guanosines. Due to its relevance to carcinogenesis, the interaction of (+)-anti-BPDE with exon 1 of the human K-ras gene has been studied in detail. Present address: Department of Physics, Drury University

  7. The effects of non-synonymous single nucleotide polymorphisms (nsSNPs) on protein-protein interactions.

    Science.gov (United States)

    Yates, Christopher M; Sternberg, Michael J E

    2013-11-01

    Non-synonymous single nucleotide polymorphisms (nsSNPs) are single base changes leading to a change to the amino acid sequence of the encoded protein. Many of these variants are associated with disease, so nsSNPs have been well studied, with studies looking at the effects of nsSNPs on individual proteins, for example, on stability and enzyme active sites. In recent years, the impact of nsSNPs upon protein-protein interactions has also been investigated, giving a greater insight into the mechanisms by which nsSNPs can lead to disease. In this review, we summarize these studies, looking at the various mechanisms by which nsSNPs can affect protein-protein interactions. We focus on structural changes that can impair interaction, changes to disorder, gain of interaction, and post-translational modifications before looking at some examples of nsSNPs at human-pathogen protein-protein interfaces and the analysis of nsSNPs from a network perspective. © 2013.

  8. Weaning from non-invasive positive pressure ventilation: Experience with progressive periods of withdraw

    Directory of Open Access Journals (Sweden)

    C. Damas

    2008-01-01

    Full Text Available Background: In recent years non-invasive ventilation (NIV as become a valuable therapeutic option in exacerbations of patients with chronic pulmonary obstructive disease. Although widely used there is a paucity of information on weaning from NIV. Objectives: We aimed to describe the performance of a weaning protocol based on progressive periods of NIV withdraw. Methods: During a one year period we performed NIV in 78 patients with acute exacerbation of chronic respiratory failure. Weaning was considered in patients with 24 hours without acidosis and respiratory rate less than 25 cycles per minute. Weaning was performed as following: during the first 24 hours in each 3 hours, one hour without NIV (except during night period, in the second day in each 3 hours, two hours without NIV (except during night period and in the third day NIV was used during the night period. Results: Sixty five patients began the weaning protocol. Mean NIV time was 120,9 hours (17 to 192 hours. No adverse effects were recorded in patients who began the weaning protocol. All patients completed the weaning protocol with no re-institution of NIV or invasive ventilation during hospitalization. Conclusions: We report an excellent weaning success rate of NIV in patients with acute severe exacerbation of CRF. Although our weaning protocol required 72 hours, our results suggest that strategies based on periods with and with-out NIV are effective. Weather similar less time consuming weaning strategies are effective, merits investigation. Resumo: Introdução: Nos últimos anos, a ventilação não invasiva (VNI tornou-se numa opção terapêutica válida nas exacerbações agudas de doentes com doença pulmonar crónica obstrutiva. No entanto, apesar de muito utilizada, existe muito pouca informação sobre o desmame deste modo ventilatório. Objectivos: Descrever um protocolo de desmame baseado em períodos progressivos de descontinuação de VNI. Métodos: Durante um ano foram

  9. Contribution from the interaction Hamiltonian to the expectation value of particle number with the non-equilibrium quantum field theory

    International Nuclear Information System (INIS)

    Hotta, Ryuuichi; Morozumi, Takuya; Takata, Hiroyuki

    2012-01-01

    We develop the method analyzing particle number non-conserving phenomena with non-equilibrium quantum field-theory. In this study, we consider a CP violating model with interaction Hamiltonian that breaks particle number conservation. To derive the quantum Boltzmann equation for the particle number, we solve Schwinger-Dyson equation, which are obtained from two particle irreducible closed-time-path (2PI CTP) effective action. In this calculation, we show the contribution from interaction Hamiltonian to the time evolution of expectation value of particle number.

  10. Comparison of Decisions Quality of Heuristic Methods with Limited Depth-First Search Techniques in the Graph Shortest Path Problem

    Directory of Open Access Journals (Sweden)

    Vatutin Eduard

    2017-12-01

    Full Text Available The article deals with the problem of analysis of effectiveness of the heuristic methods with limited depth-first search techniques of decision obtaining in the test problem of getting the shortest path in graph. The article briefly describes the group of methods based on the limit of branches number of the combinatorial search tree and limit of analyzed subtree depth used to solve the problem. The methodology of comparing experimental data for the estimation of the quality of solutions based on the performing of computational experiments with samples of graphs with pseudo-random structure and selected vertices and arcs number using the BOINC platform is considered. It also shows description of obtained experimental results which allow to identify the areas of the preferable usage of selected subset of heuristic methods depending on the size of the problem and power of constraints. It is shown that the considered pair of methods is ineffective in the selected problem and significantly inferior to the quality of solutions that are provided by ant colony optimization method and its modification with combinatorial returns.

  11. Comparison of Decisions Quality of Heuristic Methods with Limited Depth-First Search Techniques in the Graph Shortest Path Problem

    Science.gov (United States)

    Vatutin, Eduard

    2017-12-01

    The article deals with the problem of analysis of effectiveness of the heuristic methods with limited depth-first search techniques of decision obtaining in the test problem of getting the shortest path in graph. The article briefly describes the group of methods based on the limit of branches number of the combinatorial search tree and limit of analyzed subtree depth used to solve the problem. The methodology of comparing experimental data for the estimation of the quality of solutions based on the performing of computational experiments with samples of graphs with pseudo-random structure and selected vertices and arcs number using the BOINC platform is considered. It also shows description of obtained experimental results which allow to identify the areas of the preferable usage of selected subset of heuristic methods depending on the size of the problem and power of constraints. It is shown that the considered pair of methods is ineffective in the selected problem and significantly inferior to the quality of solutions that are provided by ant colony optimization method and its modification with combinatorial returns.

  12. Double Degenerates among DA white dwarfs

    International Nuclear Information System (INIS)

    Bragaglia, A.; Greggio, L.; Renzini, A.; D'odorico, S.

    1990-01-01

    The results of a spectroscopic survey of catalog white dwarfs in search of radial velocity variations indicative of a binary motion are reported. In a sample of 54 DA white dwarfs, one Double Degenerate (DD) system with a period of 1.15 days (the shortest period DD system yet discovered) is found. Two other excellent and two good DD candidates, and two white dwarf + red dwarf pairs were also found. If all the candidates should be confirmed, this would indicate a frequency of about 13 percent of interacting binaries in an unbiased sample of evolved stars, with a DD frequency of about 10 percent. These results suggest fairly large values for the common-envelope parameter alpha, implying that a source of energy other than orbital may be required to eject the envelope during common-envelope events. Finally, in combination with previous evidence our result implies that DDs with WD components of the DA variety are unlikely to be the precursors of Type I supernovae, but DDs with non-DA components remain very attractive candidates. 20 refs

  13. Improving LMA predictions with non-standard interactions: neutrino decay in solar matter?

    CERN Document Server

    Das, C R

    2010-01-01

    It has been known for some time that the well established LMA solution to the observed solar neutrino deficit fails to predict a flat energy spectrum for SuperKamiokande as opposed to what the data indicates. It also leads to a Chlorine rate which appears to be too high as compared to the data. We investigate the possible solution to these inconsistencies with non standard neutrino interactions, assuming that they come as extra contributions to the $\

  14. Dynamics of interacting qubits coupled to a common bath: Non-Markovian quantum-state-diffusion approach

    International Nuclear Information System (INIS)

    Zhao Xinyu; Jing Jun; Corn, Brittany; Yu Ting

    2011-01-01

    Non-Markovian dynamics is studied for two interacting qubits strongly coupled to a dissipative bosonic environment. We derive a non-Markovian quantum-state-diffusion (QSD) equation for the coupled two-qubit system without any approximations, and in particular, without the Markov approximation. As an application and illustration of our derived time-local QSD equation, we investigate the temporal behavior of quantum coherence dynamics. In particular, we find a strongly non-Markovian regime where entanglement generation is significantly modulated by the environmental memory. Additionally, we study residual entanglement in the steady state by analyzing the steady-state solution of the QSD equation. Finally, we discuss an approximate QSD equation.

  15. Cardiorespiratory interactions during periodic breathing in awake chronic heart failure patients.

    Science.gov (United States)

    Pinna, G D; Maestri, R; Mortara, A; La Rovere, M T

    2000-03-01

    We applied spectral techniques to the analysis of cardiorespiratory signals [instantaneous lung volume (ILV), instantaneous tidal volume (ITV), arterial O(2) saturation (Sa(O(2))) at the ear, heart rate (HR), systolic (SAP), and diastolic (DAP) arterial pressure] during nonapneic periodic breathing (PB) in 29 awake chronic heart failure (CHF) patients and estimated the timing relationships between respiratory and slow cardiovascular (cardiorespiratory interactions during PB and 2) to test the hypothesis of a central vasomotor origin of PB. All cardiovascular signals were characterized by a dominant (>/=84% of total power) oscillation at the frequency of PB (mean +/- SE: 0.022 +/- 0.0008 Hz), highly coherent (>/=0.89), and delayed with respect to ITV (ITV-HR, 2.4 +/- 0.72 s; ITV-SAP, 6.7 +/- 0.65 s; ITV-DAP, 3.2 +/- 0.61 s; P cardiorespiratory rhythm led by the ventilatory oscillation and suggest that 1) the cyclic increase in inspiratory drive and cardiopulmonary reflexes and 2) mechanical effects of PB-induced changes in intrathoracic pressure are the more likely sources of the HR and blood pressure oscillations, respectively. The timing relationship between ITV and blood pressure signals excludes the possibility that PB represents the effect of a central vasomotor rhythm.

  16. Development of Advanced Concept for Shortening Construction Period of ABWR Plant

    International Nuclear Information System (INIS)

    Hiroshi Ijichi; Toshio Yamashita; Masahiro Tsutagawa; Hiroya Mori; Nobuaki Ooshima; Jun Miura; Minoru Kanechika; Nobuaki Miura

    2002-01-01

    Construction of a nuclear power plant (NPP) requires a very long period because of large amount of construction materials and many issues for negotiation among multiple sections. Shortening the construction period advances the date of return on an investment, and can also result in reduced construction cost. Therefore, the study of this subject has a very high priority for utilities. We achieved a construction period of 37 months from the first concrete work to fuel loading (F/L) (51.5 months from the inspection of the foundation (I/F) to the start of commercial operation (C/O)) at the Kashiwazaki-Kariwa NPPs No. 6 and 7 (KK-6/7), which are the first ABWR plants in the world. At TEPCO's next plant, we think that a construction period of less than 36 months (45 months from I/F to C/O) can be realized based on conventional methods such as early start of equipment installation and blocking of equipment to be brought in advance. Furthermore, we are studying the feasibility of a 21.5-month construction period (30 months from I/F to C/O) with advanced ideas and methods. The important concepts for a 21.5-month construction period are adoption of a new building structure that is the steel plate reinforced concrete (SC) structure and promotion of extensive modularization of equipment and building structure. With introducing these new concepts, we are planning the master schedule (M/S) and finding solutions to conflicts in the schedule of area release from building construction work to equipment installation work (schedule-conflicts.) In this report, we present the shortest construction period and an effective method to put it into practice for the conventional general arrangement (GA) of ABWR. In the future, we will continue the study on the improvement of building configuration and arrangements, and make clear of the concept for large composite modules of building structures and equipment. (authors)

  17. Preparation and characterization of malonic acid cross-linked chitosan and collagen 3D scaffolds: an approach on non-covalent interactions.

    Science.gov (United States)

    Mitra, Tapas; Sailakshmi, G; Gnanamani, A; Mandal, A B

    2012-05-01

    The present study emphasizes the influence of non-covalent interactions on the mechanical and thermal properties of the scaffolds of chitosan/collagen origin. Malonic acid (MA), a bifuncitonal diacid was chosen to offer non-covalent cross-linking. Three dimensional scaffolds was prepared using chitosan at 1.0% (w/v) and MA at 0.2% (w/v), similarly collagen 0.5% (w/v) and MA 0.2% (w/v) and characterized. Results on FT-IR, TGA, DSC, SEM and mechanical properties (tensile strength, stiffness, Young's modulus, etc.) assessment demonstrated the existence of non-covalent interaction between MA and chitosan/collagen, which offered flexibility and high strength to the scaffolds suitable for tissue engineering research. Studies using NIH 3T3 fibroblast cells suggested biocompatibility nature of the scaffolds. Docking simulation study further supports the intermolecular hydrogen bonding interactions between MA and chitosan/collagen.

  18. Flavor non-universal gauge interactions and anomalies in B-meson decays

    Science.gov (United States)

    Tang, Yong; Wu, Yue-Liang

    2018-02-01

    Motivated by flavor non-universality and anomalies in semi-leptonic B-meson decays, we present a general and systematic discussion about how to construct anomaly-free U(1)‧ gauge theories based on an extended standard model with only three right-handed neutrinos. If all standard model fermions are vector-like under this new gauge symmetry, the most general family non-universal charge assignments, (a,b,c) for three-generation quarks and (d,e,f) for leptons, need satisfy just one condition to be anomaly-free, 3(a+b+c) = - (d+e+f). Any assignment can be linear combinations of five independent anomaly-free solutions. We also illustrate how such models can generally lead to flavor-changing interactions and easily resolve the anomalies in B-meson decays. Probes with {{B}}{s} - {{\\bar B}}{s} mixing, decay into τ ±, dilepton and dijet searches at colliders are also discussed. Supported by the Grant-in-Aid for Innovative Areas (16H06490)

  19. Long Non-Coding RNAs: Emerging and Versatile Regulators in Host–Virus Interactions

    Directory of Open Access Journals (Sweden)

    Xing-Yu Meng

    2017-11-01

    Full Text Available Long non-coding RNAs (lncRNAs are a class of non-protein-coding RNA molecules, which are involved in various biological processes, including chromatin modification, cell differentiation, pre-mRNA transcription and splicing, protein translation, etc. During the last decade, increasing evidence has suggested the involvement of lncRNAs in both immune and antiviral responses as positive or negative regulators. The immunity-associated lncRNAs modulate diverse and multilayered immune checkpoints, including activation or repression of innate immune signaling components, such as interleukin (IL-8, IL-10, retinoic acid inducible gene I, toll-like receptors 1, 3, and 8, and interferon (IFN regulatory factor 7, transcriptional regulation of various IFN-stimulated genes, and initiation of the cell apoptosis pathways. Additionally, some virus-encoded lncRNAs facilitate viral replication through individually or synergistically inhibiting the host antiviral responses or regulating multiple steps of the virus life cycle. Moreover, some viruses are reported to hijack host-encoded lncRNAs to establish persistent infections. Based on these amazing discoveries, lncRNAs are an emerging hotspot in host–virus interactions. In this review, we summarized the current findings of the host- or virus-encoded lncRNAs and the underlying mechanisms, discussed their impacts on immune responses and viral replication, and highlighted their critical roles in host–virus interactions.

  20. Momentum distribution of non-interacting fermions enclosed in a box

    International Nuclear Information System (INIS)

    Krivine, H.

    1985-01-01

    This is a study of: the finite size effect on the momentum distribution n(/sup →/k) of an ensemble of A non-interacting fermions enclosed in a box. Analytical expressions are obtained in the two limiting cases the Fermi momentum. The result is to analyze the convergence of toward the standard step function in the infinite medium. Applying results to the nuclear case, changes are compared in n(/sup →/k) generated by the finite size of actual nuclei to those due to short range correlations. Both effects are shown to be of same order of magnitude. The next step is to take into account the short range correlations in finite systems

  1. Mammalian cycles: internally defined periods and interaction-driven amplitudes

    Directory of Open Access Journals (Sweden)

    LR Ginzburg

    2015-08-01

    Full Text Available The cause of mammalian cycles—the rise and fall of populations over a predictable period of time—has remained controversial since these patterns were first observed over a century ago. In spite of extensive work on observable mammalian cycles, the field has remained divided upon what the true cause is, with a majority of opinions attributing it to either predation or to intra-species mechanisms. Here we unite the eigenperiod hypothesis, which describes an internal, maternal effect-based mechanism to explain the cycles’ periods with a recent generalization explaining the amplitude of snowshoe hare cycles in northwestern North America based on initial predator abundance. By explaining the period and the amplitude of the cycle with separate mechanisms, a unified and consistent view of the causation of cycles is reached. Based on our suggested theory, we forecast the next snowshoe hare cycle (predicted peak in 2016 to be of extraordinarily low amplitude.

  2. Non-equilibrium ionization by a periodic electron beam. II. Synthetic Si IV and O IV transition region spectra

    Science.gov (United States)

    Dzifčáková, Elena; Dudík, Jaroslav

    2018-03-01

    Context. Transition region (TR) spectra typically show the Si IV 1402.8 Å line to be enhanced by a factor of 5 or more compared to the neighboring O IV 1401.2 Å, contrary to predictions of ionization equilibrium models and the Maxwellian distribution of particle energies. Non-equilibrium effects in TR spectra are therefore expected. Aims: To investigate the combination of non-equilibrium ionization and high-energy particles, we apply the model of the periodic electron beam, represented by a κ-distribution that recurs at periods of several seconds, to plasma at chromospheric temperatures of 104 K. This simple model can approximate a burst of energy release involving accelerated particles. Methods: Instantaneous time-dependent charge states of silicon and oxygen were calculated and used to synthesize the instantaneous and period-averaged spectra of Si IV and O IV. Results: The electron beam drives the plasma out of equilibrium. At electron densities of Ne = 1010 cm-3, the plasma is out of ionization equilibrium at all times in all cases we considered, while for a higher density of Ne = 1011 cm-3, ionization equilibrium can be reached toward the end of each period, depending on the conditions. In turn, the character of the period-averaged synthetic spectra also depends on the properties of the beam. While the case of κ = 2 results in spectra with strong or even dominant O IV, higher values of κ can approximate a range of observed TR spectra. Spectra similar to typically observed spectra, with the Si IV 1402.8 Å line about a factor 5 higher than O IV 1401.2 Å, are obtained for κ = 3. An even higher value of κ = 5 results in spectra that are exclusively dominated by Si IV, with negligible O IV emission. This is a possible interpretation of the TR spectra of UV (Ellerman) bursts, although an interpretation that requires a density that is 1-3 orders of magnitude lower than for equilibrium estimates. Movies associated to Fig. A.1 are available at http://https://www.aanda.org

  3. Strategic interaction between government and central bank in framework of cooperative and non-cooperative games

    NARCIS (Netherlands)

    Mahmoudinia, D.; Engwerda, Jacob; Esfahani, Rahim Dallali; Dastjerdi, R.B.; Fakhar, M.

    2016-01-01

    In this paper we analyzed the strategic interaction between government and central bank in Iranian economy. Using dynamic differential games and Nash equilibrium within cooperative and non-cooperative setting, we try to find the optimal values of debt, deficit and monetary base. The results of

  4. Probing non nucleonic degrees of freedom with strong and electromagnetic interactions

    International Nuclear Information System (INIS)

    Frois, B.

    1985-10-01

    In this talk, I would like to examine our present view on non-nucleonic degrees of freedom with a few typical experimental results obtained recently both with hadronic and electromagnetic probes at intermediate energies. It is the first generation of experimental data which has probed mesonic degrees of freedom with a spatial resolution of the order of 0.5 fm. This has made possible for example the measurement of the size of the pion-nucleon interaction region. This is very stimulating progress and we begin to have a coherent overview on the various reaction mechanisms which are induced by hadronic and electromagnetic probes

  5. Non-orthogonal configuration interaction for the calculation of multielectron excited states

    Energy Technology Data Exchange (ETDEWEB)

    Sundstrom, Eric J., E-mail: eric.jon.sundstrom@berkeley.edu; Head-Gordon, Martin [Department of Chemistry, University of California Berkeley, Berkeley, California 94720, USA and Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States)

    2014-03-21

    We apply Non-orthogonal Configuration Interaction (NOCI) to molecular systems where multielectron excitations, in this case double excitations, play a substantial role: the linear polyenes and β-carotene. We demonstrate that NOCI when applied to systems with extended conjugation, provides a qualitatively correct wavefunction at a fraction of the cost of many other multireference treatments. We also present a new extension to this method allowing for purification of higher-order spin states by utilizing Generalized Hartree-Fock Slater determinants and the details for computing 〈S{sup 2}〉 for the ground and excited states.

  6. Commuting periodic operators and the periodic Wigner function

    International Nuclear Information System (INIS)

    Zak, J

    2004-01-01

    Commuting periodic operators (CPO) depending on the coordinate x-hat and the momentum p-hat operators are defined. The CPO are functions of the two basic commuting operators exp(i x-hat 2π/a) and exp(i/h p-hat a), with a being an arbitrary constant. A periodic Wigner function (PWF) w(x, p) is defined and it is shown that it is applicable in a normal expectation value calculation to the CPO, as done in the original Wigner paper. Moreover, this PWF is non-negative everywhere, and it can therefore be interpreted as an actual probability distribution. The PWF w(x, p) is shown to be given as an expectation value of the periodic Dirac delta function in the phase plane. (letter to the editor)

  7. Flame-vortex interaction and mixing behaviors of turbulent non-premixed jet flames under acoustic forcing

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Munki; Choi, Youngil; Oh, Jeongseog; Yoon, Youngbin [School of Mechanical and Aerospace Engineering, Seoul National University, Seoul (Korea)

    2009-12-15

    This study examines the effect of acoustic excitation using forced coaxial air on the flame characteristics of turbulent hydrogen non-premixed flames. A resonance frequency was selected to acoustically excite the coaxial air jet due to its ability to effectively amplify the acoustic amplitude and reduce flame length and NO{sub x} emissions. Acoustic excitation causes the flame length to decrease by 15% and consequently, a 25% reduction in EINO{sub x} is achieved, compared to coaxial air flames without acoustic excitation at the same coaxial air to fuel velocity ratio. Moreover, acoustic excitation induces periodical fluctuation of the coaxial air velocity, thus resulting in slight fluctuation of the fuel velocity. From phase-lock PIV and OH PLIF measurement, the local flow properties at the flame surface were investigated under acoustic forcing. During flame-vortex interaction in the near field region, the entrainment velocity and the flame surface area increased locally near the vortex. This increase in flame surface area and entrainment velocity is believed to be a crucial factor in reducing flame length and NO{sub x} emission in coaxial jet flames with acoustic excitation. Local flame extinction occurred frequently when subjected to an excessive strain rate, indicating that intense mass transfer of fuel and air occurs radially inward at the flame surface. (author)

  8. Evaluation of the Usefulness of Restricted Respiratory Period at the Time of Radiotherapy for Non-Small Cell Lung Cancer Patient

    Energy Technology Data Exchange (ETDEWEB)

    Park, So Yeon; Ahn, Jong Ho; Kim, Yung Il; Kim, Jin Man; Choi, Byung Ki; Pyo, Hong Ryul; Song, Ki Won [Dept. of Radiation Oncology, Samsung Medical Center, Seoul (Korea, Republic of); Suh, Jung Min [Dept. of Radiological Science, Daewon University Colloge, Jecheon (Korea, Republic of)

    2012-09-15

    It is essential to minimize the movement of tumor due to respiratory movement at the time of respiration controlled radiotherapy of non-small cell lung cancer patient. Accordingly, this Study aims to evaluate the usefulness of restricted respiratory period by comparing and analyzing the treatment plans that apply free and restricted respiration period respectively. After having conducted training on 9 non-small cell lung cancer patients (tumor n=10) from April to December 2011 by using 'signal monitored-breathing (guided- breathing)' method for the 'free respiratory period' measured on the basis of the regular respiratory period of the patents and 'restricted respiratory period' that was intentionally reduced, total of 10 CT images for each of the respiration phases were acquired by carrying out 4D CT for treatment planning purpose by using RPM and 4-dimensional computed tomography simulator. Visual gross tumor volume (GTV) and internal target volume (ITV) that each of the observer 1 and observer 2 has set were measured and compared on the CT image of each respiratory interval. Moreover, the amplitude of movement of tumor was measured by measuring the center of mass (COM) at the phase of 0% which is the end-inspiration (EI) and at the phase of 50% which is the end-exhalation (EE). In addition, both observers established treatment plan that applied the 2 respiratory periods, and mean dose to normal lung (MDTNL) was compared and analyzed through dose-volume histogram (DVH). Moreover, normal tissue complication probability (NTCP) of the normal lung volume was compared by using dose-volume histogram analysis program (DVH analyzer v.1) and statistical analysis was performed in order to carry out quantitative evaluation of the measured data. As the result of the analysis of the treatment plan that applied the 'restricted respiratory period' of the observer 1 and observer 2, there was reduction rate of 38.75% in the 3-dimensional

  9. Evaluation of the Usefulness of Restricted Respiratory Period at the Time of Radiotherapy for Non-Small Cell Lung Cancer Patient

    International Nuclear Information System (INIS)

    Park, So Yeon; Ahn, Jong Ho; Kim, Yung Il; Kim, Jin Man; Choi, Byung Ki; Pyo, Hong Ryul; Song, Ki Won; Suh, Jung Min

    2012-01-01

    It is essential to minimize the movement of tumor due to respiratory movement at the time of respiration controlled radiotherapy of non-small cell lung cancer patient. Accordingly, this Study aims to evaluate the usefulness of restricted respiratory period by comparing and analyzing the treatment plans that apply free and restricted respiration period respectively. After having conducted training on 9 non-small cell lung cancer patients (tumor n=10) from April to December 2011 by using 'signal monitored-breathing (guided- breathing)' method for the 'free respiratory period' measured on the basis of the regular respiratory period of the patents and 'restricted respiratory period' that was intentionally reduced, total of 10 CT images for each of the respiration phases were acquired by carrying out 4D CT for treatment planning purpose by using RPM and 4-dimensional computed tomography simulator. Visual gross tumor volume (GTV) and internal target volume (ITV) that each of the observer 1 and observer 2 has set were measured and compared on the CT image of each respiratory interval. Moreover, the amplitude of movement of tumor was measured by measuring the center of mass (COM) at the phase of 0% which is the end-inspiration (EI) and at the phase of 50% which is the end-exhalation (EE). In addition, both observers established treatment plan that applied the 2 respiratory periods, and mean dose to normal lung (MDTNL) was compared and analyzed through dose-volume histogram (DVH). Moreover, normal tissue complication probability (NTCP) of the normal lung volume was compared by using dose-volume histogram analysis program (DVH analyzer v.1) and statistical analysis was performed in order to carry out quantitative evaluation of the measured data. As the result of the analysis of the treatment plan that applied the 'restricted respiratory period' of the observer 1 and observer 2, there was reduction rate of 38.75% in the 3-dimensional direction movement of the tumor in

  10. Social interaction recruits mentalizing and reward systems in middle childhood.

    Science.gov (United States)

    Alkire, Diana; Levitas, Daniel; Warnell, Katherine Rice; Redcay, Elizabeth

    2018-06-08

    Social cognition develops in the context of reciprocal social interaction. However, most neuroimaging studies of mentalizing have used noninteractive tasks that may fail to capture important aspects of real-world mentalizing. In adults, social-interactive context modulates activity in regions linked to social cognition and reward, but few interactive studies have been done with children. The current fMRI study examines children aged 8-12 using a novel paradigm in which children believed they were interacting online with a peer. We compared mental and non-mental state reasoning about a live partner (Peer) versus a story character (Character), testing the effects of mentalizing and social interaction in a 2 × 2 design. Mental versus Non-Mental reasoning engaged regions identified in prior mentalizing studies, including the temporoparietal junction, superior temporal sulcus, and dorsomedial prefrontal cortex. Moreover, peer interaction, even in conditions without explicit mentalizing demands, activated many of the same mentalizing regions. Peer interaction also activated areas outside the traditional mentalizing network, including the reward system. Our results demonstrate that social interaction engages multiple neural systems during middle childhood and contribute further evidence that social-interactive paradigms are needed to fully capture how the brain supports social processing in the real world. © 2018 Wiley Periodicals, Inc.

  11. LHC Interaction Region Upgrade Phase I

    CERN Document Server

    Ostojic, R

    2009-01-01

    The LHC is starting operation with beam in 2008. The primary goal of CERN and the LHC community is to ensure that the collider is operated efficiently, maximizing its physics reach, and to achieve the nominal performance in the shortest term. Since several years the community has been discussing the directions for upgrading the experiments, in particular ATLAS and CMS, the LHC machine and the CERN proton injector complex. A well substantiated and coherent scenario for the first phase of the upgrade, which is foreseen in 2013, is now approved by CERN Council. In this paper, we present the goals and the proposed conceptual solution for the Phase-I upgrade of the LHC interaction regions. This phase relies on the mature Nb-Ti superconducting magnet technology, with the target of increasing the luminosity by a factor of 2-3 with respect to the nominal luminosity of 1034 cm-2s-1, while maximising the use of the existing infrastructure.

  12. Many-body current formula and current conservation for non-equilibrium fully interacting nanojunctions

    International Nuclear Information System (INIS)

    Ness, H; Dash, L K

    2012-01-01

    We consider the electron transport properties through fully interacting nanoscale junctions beyond the linear-response regime. We calculate the current flowing through an interacting region connected to two interacting leads, with interaction crossing at the left and right contacts, by using a non-equilibrium Green function technique. The total current at one interface (the left one for example) is made of several terms which can be regrouped into two sets. The first set corresponds to a very generalized Landauer-like current formula with physical quantities defined only in the interacting central region and with renormalized lead self-energies. The second set characterizes inelastic scattering events occurring in the left lead. We show how this term can be negligible or even vanish due to the pseudo-equilibrium statistical properties of the lead in the thermodynamic limit. The expressions for the different Green functions needed for practical calculations of the current are also provided. We determine the constraints imposed by the physical condition of current conservation. The corresponding equation imposed on the different self-energy quantities arising from the current conservation is derived. We discuss in detail its physical interpretation and its relation with previously derived expressions. Finally several important key features are discussed in relation to the implementation of our formalism for calculations of quantum transport in realistic systems. (paper)

  13. Influence of blood glucose level, age and fasting period on non-pathological FDG uptake in heart and gut

    International Nuclear Information System (INIS)

    Groot, Michel de; Meeuwis, Antoi P.W.; Kok, Peter J.M.; Corstens, Frans H.M.; Oyen, Wim J.G.

    2005-01-01

    Increased, non-pathological FDG uptake in myocardium, stomach and bowel is frequently observed while performing clinical positron emission tomography (PET) studies. This ''physiological'' increased FDG uptake is not related to (oncological) disease and is unwanted since it may interfere with correct image reading. We evaluated the role of several patient-related factors that may have an influence on this phenomenon. One hundred and seventy-five non-diabetic patients with malignant diseases, referred to our department for routine whole-body FDG-PET, were retrospectively evaluated. Age, blood glucose levels and duration of the fasting period were recorded. FDG uptake in myocardium, bowel and stomach was visually graded. Statistical analysis showed that increased FDG uptake in myocardium, bowel and stomach was not significantly correlated to blood glucose level, age or duration of fasting. Most patients who underwent repeated PET scans (92 scans in 25 patients), showed no or minor changes in uptake in bowel and stomach on the consecutive scans, while myocardial uptake was more variable. Age, fasting period and blood glucose levels did not influence physiological uptake. However, there seemed to be a patient-specific pattern for stomach and bowel uptake. (orig.)

  14. Scaled MP3 non-covalent interaction energies agree closely with accurate CCSD(T) benchmark data.

    Science.gov (United States)

    Pitonák, Michal; Neogrády, Pavel; Cerný, Jirí; Grimme, Stefan; Hobza, Pavel

    2009-01-12

    Scaled MP3 interaction energies calculated as a sum of MP2/CBS (complete basis set limit) interaction energies and scaled third-order energy contributions obtained in small or medium size basis sets agree very closely with the estimated CCSD(T)/CBS interaction energies for the 22 H-bonded, dispersion-controlled and mixed non-covalent complexes from the S22 data set. Performance of this so-called MP2.5 (third-order scaling factor of 0.5) method has also been tested for 33 nucleic acid base pairs and two stacked conformers of porphine dimer. In all the test cases, performance of the MP2.5 method was shown to be superior to the scaled spin-component MP2 based methods, e.g. SCS-MP2, SCSN-MP2 and SCS(MI)-MP2. In particular, a very balanced treatment of hydrogen-bonded compared to stacked complexes is achieved with MP2.5. The main advantage of the approach is that it employs only a single empirical parameter and is thus biased by two rigorously defined, asymptotically correct ab-initio methods, MP2 and MP3. The method is proposed as an accurate but computationally feasible alternative to CCSD(T) for the computation of the properties of various kinds of non-covalently bound systems.

  15. Negative Symptoms and Avoidance of Social Interaction: A Study of Non-Verbal Behaviour.

    Science.gov (United States)

    Worswick, Elizabeth; Dimic, Sara; Wildgrube, Christiane; Priebe, Stefan

    2018-01-01

    Non-verbal behaviour is fundamental to social interaction. Patients with schizophrenia display an expressivity deficit of non-verbal behaviour, exhibiting behaviour that differs from both healthy subjects and patients with different psychiatric diagnoses. The present study aimed to explore the association between non-verbal behaviour and symptom domains, overcoming methodological shortcomings of previous studies. Standardised interviews with 63 outpatients diagnosed with schizophrenia were videotaped. Symptoms were assessed using the Clinical Assessment Interview for Negative Symptoms (CAINS), the Positive and Negative Syndrome Scale (PANSS) and the Calgary Depression Scale. Independent raters later analysed the videos for non-verbal behaviour, using a modified version of the Ethological Coding System for Interviews (ECSI). Patients with a higher level of negative symptoms displayed significantly fewer prosocial (e.g., nodding and smiling), gesture, and displacement behaviours (e.g., fumbling), but significantly more flight behaviours (e.g., looking away, freezing). No gender differences were found, and these associations held true when adjusted for antipsychotic medication dosage. Negative symptoms are associated with both a lower level of actively engaging non-verbal behaviour and an increased active avoidance of social contact. Future research should aim to identify the mechanisms behind flight behaviour, with implications for the development of treatments to improve social functioning. © 2017 S. Karger AG, Basel.

  16. " Blaming, shaming, humiliation": Stigmatising medical interactions among people with non-epileptic seizures.

    Science.gov (United States)

    Robson, Catherine; Lian, Olaug S

    2017-01-01

    Background : People with non-epileptic seizures (NES) describe challenging relationships with health professionals, and explain negative interactions as common and expected. Despite these difficulties, little is known about how people with NES experience difficult healthcare encounters. Methods : Using a thematic discourse analysis approach, we analysed the free-text survey responses of 135 people with NES and asked: what kind of challenges do people living with this condition encounter when interacting with health professionals, and how do they experience the consequences of difficult interactions? We explore their experiences by interpreting the latent meaning of participants' texts from a social-constructionist perspective on health and illness. Results : The overarching narrative depicts a fundamental breakdown in patient-provider relationships. According to our data, the negative experiences of study participants emerge from more than practitioners' lack of awareness of NES and access to information about the condition - to the extent that it is available. In examining the challenges people with NES encounter when interacting with health professionals, their main experiences centre on blame and humiliation. When exploring their experiences, theories of stigma serve as a useful theoretical framework. Conclusions : Normative judgements arising from psychogenic understandings of NES are stigmatising and restrict professional displays of respectful (patient-centred) care. Those with the condition depict being negatively stereotyped, illegitimated and held morally culpable by health professionals. Perceived to lack medical, moral and credible status, participants describe practitioners who treat them with disrespect, and some recount conduct that defies all ethical and professional obligations and standards. These encounters can have wide-ranging adverse consequences for patients: emotionally, physically, and for their future healthcare. The quality of healthcare

  17. VLBI observations of the shortest orbital period black hole binary, MAXI J1659-152

    NARCIS (Netherlands)

    Paragi, Z.; van der Horst, A.J.; Belloni, T.; Miller-Jones, J.C.A.; Linford, J.; Taylor, G.; Yang, J.; Garrett, M.A.; Granot, J.; Kouveliotou, C.; Kuulkers, E.; Wijers, R.A.M.J.

    2013-01-01

    The X-ray transient MAXI J1659−152 was discovered by Swift/Burst Alert Telescope and it was initially identified as a gamma-ray burst. Soon its Galactic origin and binary nature were established. There exists a wealth of multiwavelength monitoring data for this source, providing a great coverage of

  18. Emergency Diesel Generation System Surveillance Test Policy Optimization Through Genetic Algorithms Using Non-Periodic Intervention Frequencies and Seasonal Constraints

    International Nuclear Information System (INIS)

    Lapa, Celso M.F.; Pereira, Claudio M.N.A.; Frutuoso e Melo, P.F.

    2002-01-01

    Nuclear standby safety systems must frequently, be submitted to periodic surveillance tests. The main reason is to detect, as soon as possible, the occurrence of unrevealed failure states. Such interventions may, however, affect the overall system availability due to component outages. Besides, as the components are demanded, deterioration by aging may occur, penalizing again the system performance. By these reasons, planning a good surveillance test policy implies in a trade-off between gains and overheads due to the surveillance test interventions. In order maximize the systems average availability during a given period of time, it has recently been developed a non-periodic surveillance test optimization methodology based on genetic algorithms (GA). The fact of allowing non-periodic tests turns the solution space much more flexible and schedules can be better adjusted, providing gains in the overall system average availability, when compared to those obtained by an optimized periodic tests scheme. The optimization problem becomes, however, more complex. Hence, the use of a powerful optimization technique, such as GAs, is required. Some particular features of certain systems can turn it advisable to introduce other specific constraints in the optimization problem. The Emergency Diesel Generation System (EDGS) of a Nuclear Power Plant (N-PP) is a good example for demonstrating the introduction of seasonal constraints in the optimization problem. This system is responsible for power supply during an external blackout. Therefore, it is desirable during periods of high blackout probability to maintain the system availability as high as possible. Previous applications have demonstrated the robustness and effectiveness of the methodology. However, no seasonal constraints have ever been imposed. This work aims at investigating the application of such methodology in the Angra-II Brazilian NPP EDGS surveillance test policy optimization, considering the blackout probability

  19. Forage and sugar in dairy calves' starter diet and their interaction on performance, weaning age and rumen fermentation.

    Science.gov (United States)

    Beiranvand, H; Ghorbani, G R; Khorvash, M; Kazemi-Bonchenari, M

    2014-06-01

    The effects of sugar and forage inclusion in calves' starter and their interaction on animal performance and rumen fermentation parameters were investigated. Twenty-eight neonatal Holstein male calves 3 days of age with average body weights of 42 ± 4 kg were allocated to four different treatments. All calves were fed a similar basal diet consisting of milk and concentrate. The experimental treatments were: (i) basal diet with no supplementation (Control, hereafter designated by C), (ii) basal diet plus 5% granular sugar cane (Sugar, designated by S), (iii) basal diet plus 5% forage (Forage, designated by F) and (iv) basal diet plus 5% forage with 5% granular sugar cane (F × S). Supplement ingredients were used on a dry matter (DM) basis. Rumen fluid parameters were measured twice on days 35 and 70 of the study period. The calves were weaned when they could consume 1 kg of starter for three consecutive days. The results show that starter intake was not affected by treatment; however, the lowest ADG was observed with calves in the sugar treatment. Weaning age was affected by treatments, and forage showed to reduce milk consumption period down to its shortest. Forage-sugar interaction was found to have no effects on animal performance. The structural body indices as well as the health status of the calves were similar in different treatments. Rumen pH did not differ among the treatment groups. Among the rumen parameters, total VFA concentration and molar proportions of butyrate and propionate did not exhibit any significant differences among the treatments. However, ruminal acetate concentration decreased in calves that fed sugar cane during the early weeks of the study period. Comparison of forage and sugar included in the starter diets revealed that forage reduced weaning age, while sugar cane had a negative effect on calves' performance. Journal of Animal Physiology and Animal Nutrition © 2013 Blackwell Verlag GmbH.

  20. Oblique interaction of a laminar vortex ring with a non-deformable free surface: Vortex reconnection and breakdown

    International Nuclear Information System (INIS)

    Balakrishnan, S K; Thomas, T G; Coleman, G N

    2011-01-01

    Direct Numerical Simulation (DNS) is used to study the interaction of a laminar vortex ring with a non-deformable, free-slip surface at an oblique angle of incidence. The interaction leads to the well-known phenomenon of vortex reconnection. It was found that the reconnection process leads to rapid production of small-scale vortical structures. This phenomenon was found to be related to the kinematics of the reconection process.

  1. RADIAL VELOCITY PLANETS DE-ALIASED: A NEW, SHORT PERIOD FOR SUPER-EARTH 55 Cnc e

    International Nuclear Information System (INIS)

    Dawson, Rebekah I.; Fabrycky, Daniel C.

    2010-01-01

    Radial velocity measurements of stellar reflex motion have revealed many extrasolar planets, but gaps in the observations produce aliases, spurious frequencies that are frequently confused with the planets' orbital frequencies. In the case of Gl 581 d, the distinction between an alias and the true frequency was the distinction between a frozen, dead planet and a planet possibly hospitable to life. To improve the characterization of planetary systems, we describe how aliases originate and present a new approach for distinguishing between orbital frequencies and their aliases. Our approach harnesses features in the spectral window function to compare the amplitude and phase of predicted aliases with peaks present in the data. We apply it to confirm prior alias distinctions for the planets GJ 876 d and HD 75898 b. We find that the true periods of Gl 581 d and HD 73526 b/c remain ambiguous. We revise the periods of HD 156668 b and 55 Cnc e, which were afflicted by daily aliases. For HD 156668 b, the correct period is 1.2699 days and the minimum mass is (3.1 ± 0.4) M + . For 55 Cnc e, the correct period is 0.7365 days-the shortest of any known planet-and the minimum mass is (8.3 ± 0.3) M + . This revision produces a significantly improved five-planet Keplerian fit for 55 Cnc, and a self-consistent dynamical fit describes the data just as well. As radial velocity techniques push to ever-smaller planets, often found in systems of multiple planets, distinguishing true periods from aliases will become increasingly important.

  2. A HISTOPATHOLOGICAL STUDY OF NON-NEOPLASTIC AND NEOPLASTIC LESIONS OF KIDNEY FOR A PERIOD OF TWO YEARS

    Directory of Open Access Journals (Sweden)

    Jagadeeswari Suvvari

    2018-01-01

    Full Text Available BACKGROUND Nephrectomy is a common procedure in surgical practice. There are many indications for nephrectomy, non-neoplastic and neoplastic conditions. The common conditions being chronic pyelonephritis and renal tumours. A detailed and meticulous histopathological examination is essential to establish the diagnosis of lesions of kidney. MATERIALS AND METHODS It is a retrospective study for a period of two years from January 2015 to December 2016 at a tertiary care centre. 34 cases of nephrectomy specimens were analysed and data recorded. RESULTS Non-neoplastic lesions were constituting 47.05% (16 of cases and 52.94% (18 cases were neoplastic lesions. Lesions were more common in females with male:female ratio of 1:1.4. Both the lesions were common in age group of 41-50 years. CONCLUSION The prevalence of neoplastic lesions was more common than non-neoplastic lesions. The commonest indication for nephrectomy was chronic pyelonephritis followed by renal tumours. Histopathological examination in correlation with clinical and radiological features plays a great role in subcategorisation of lesions accurately to ensure better therapy.

  3. Non-equilibrium ionization by a periodic electron beam. I. Synthetic coronal spectra and implications for interpretation of observations

    Science.gov (United States)

    Dzifčáková, E.; Dudík, J.; Mackovjak, Š.

    2016-05-01

    Context. Coronal heating is currently thought to proceed via the mechanism of nanoflares, small-scale and possibly recurring heating events that release magnetic energy. Aims: We investigate the effects of a periodic high-energy electron beam on the synthetic spectra of coronal Fe ions. Methods: Initially, the coronal plasma is assumed to be Maxwellian with a temperature of 1 MK. The high-energy beam, described by a κ-distribution, is then switched on every period P for the duration of P/ 2. The periods are on the order of several tens of seconds, similar to exposure times or cadences of space-borne spectrometers. Ionization, recombination, and excitation rates for the respective distributions are used to calculate the resulting non-equilibrium ionization state of Fe and the instantaneous and period-averaged synthetic spectra. Results: Under the presence of the periodic electron beam, the plasma is out of ionization equilibrium at all times. The resulting spectra averaged over one period are almost always multithermal if interpreted in terms of ionization equilibrium for either a Maxwellian or a κ-distribution. Exceptions occur, however; the EM-loci curves appear to have a nearly isothermal crossing-point for some values of κs. The instantaneous spectra show fast changes in intensities of some lines, especially those formed outside of the peak of the respective EM(T) distributions if the ionization equilibrium is assumed. Movies 1-5 are available in electronic form at http://www.aanda.org

  4. Numerical Analyses of Subsoil-structure Interaction in Original Non-commercial Software based on FEM

    Science.gov (United States)

    Cajka, R.; Vaskova, J.; Vasek, J.

    2018-04-01

    For decades attention has been paid to interaction of foundation structures and subsoil and development of interaction models. Given that analytical solutions of subsoil-structure interaction could be deduced only for some simple shapes of load, analytical solutions are increasingly being replaced by numerical solutions (eg. FEM – Finite element method). Numerical analyses provides greater possibilities for taking into account the real factors involved in the subsoil-structure interaction and was also used in this article. This makes it possible to design the foundation structures more efficiently and still reliably and securely. Currently there are several software that, can deal with the interaction of foundations and subsoil. It has been demonstrated that non-commercial software called MKPINTER (created by Cajka) provides appropriately results close to actual measured values. In MKPINTER software stress-strain analysis of elastic half-space by means of Gauss numerical integration and Jacobean of transformation is done. Input data for numerical analysis were observed by experimental loading test of concrete slab. The loading was performed using unique experimental equipment which was constructed in the area Faculty of Civil Engineering, VŠB-TU Ostrava. The purpose of this paper is to compare resulting deformation of the slab with values observed during experimental loading test.

  5. Host Plant-Herbivore-Predator Interactions in Chrysoperla carnea (Neuroptera: Chrysopidae) and Myzus persicae (Homoptera: Aphididae) on Four Plant Species Under Laboratory Conditions.

    Science.gov (United States)

    Farrokhi, Milad; Gharekhani, Gholamhossein; Iranipour, Shahzad; Hassanpour, Mahdi

    2017-12-05

    The common green lacewing, Chrysoperla carnea (Stephens) (Neuroptera: Chrysopidae), is a well-known biocontrol agent. The current study examined host plant-herbivore-predator interactions with C. carnea and Myzus persicae on four host plants (peach, almond, pepper, and potato). The experiments were carried out at 25 ± 1°C and 65 ± 5% RH at a photoperiod of 16:8 (L:D) h). Duration of the preadult growth period, adult longevity, fecundity, and population growth parameters were analyzed based on the age-stage, two-sex life table theory. The shortest and longest preadult developmental times of the predator were observed on the peach and potato, respectively. The highest and lowest predation rate, oviposition period, and male and female longevity of predator were also observed on the peach and potato, respectively. The lowest intrinsic rate of increase (r) and finite rate of increase (λ) were observed on the potato (0.1087 and 1.11 d-1, respectively) and the highest on the peach (0.1460 and 1.15 d-1, respectively). The maximum and minimum mean generation times (T) were 41.84 and 35.59 d in the potato and peach, respectively. Overall, peach was found to be a more appropriate host than the other host plants for development and predation fitness of C. carnea. These findings reveal that information on tritrophic interactions and subsequent life table evaluation of natural enemies improves integrated pest management programs. Published by Oxford University Press on behalf of Entomological Society of America 2017. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  6. A non-perturbative approach to jet cross-sections and a new model for hadron-hadron interactions

    International Nuclear Information System (INIS)

    Andersson, B.

    1986-01-01

    The author discusses two subjects in this work. The first is a description of a non-perturbative approach to calculate the probabilities to obtain a particular state of confined force field in a hard interaction like e/sup +/e/sup -/ annihilation. This approach has been discussed previously by the author. There are at this time many more results of the program, in particular, some rather puzzling and disturbing ones as compared to the results obtained in perturbative QCD. The second subject is a new approach to hadron-hadron inelastic scattering. A model for these interactions based upon multiple perturbative parton interactions and subsequent string-stretching and breaking has been formulated by others in earlier works

  7. Increasing sensitivity of arc-induced long-period gratings—pushing the fabrication technique toward its limits

    International Nuclear Information System (INIS)

    Smietana, M; Bock, W J; Mikulic, P; Chen, J

    2011-01-01

    This paper presents an investigation of the sensing properties of long-period gratings (LPGs) written with the electric-arc technique in commonly used standard germanium-doped Corning SMF28 and boron co-doped Fibercore PS1250/1500 fibers. In order to increase the sensitivity of the LPGs, we studied and established for each fiber the writing parameters allowing for the coupling of the highest possible order of cladding modes at a resonance wavelength around λ = 1550 nm. The sensitivity of the LPGs to refractive index, to temperature and to hydrostatic pressure was investigated. The experimental results were supported by extensive numerical simulations. Thanks to the well-established and precisely controlled arc-writing process, we were able to reduce the minimum period of the gratings down to 345 and 221 µm, respectively, for LPGs based on the SMF28 and PS1250/1500 fibers. To the best of our knowledge, these are the shortest periods ever achieved for these fibers using the arc-manufacturing technique. The pressure sensitivities of 13 and 220 pm bar −1 are the highest ever measured for LPGs written in the SMF28 and PS1250/1500 fibers, respectively. Moreover, a reduction in the diameters of the SMF28 fiber induced by the arc was found, which significantly affected the distribution of resonances generated by the coupled cladding modes

  8. Roles of Non-Coding RNA in Sugarcane-Microbe Interaction.

    Science.gov (United States)

    Thiebaut, Flávia; Rojas, Cristian A; Grativol, Clícia; Calixto, Edmundo P da R; Motta, Mariana R; Ballesteros, Helkin G F; Peixoto, Barbara; de Lima, Berenice N S; Vieira, Lucas M; Walter, Maria Emilia; de Armas, Elvismary M; Entenza, Júlio O P; Lifschitz, Sergio; Farinelli, Laurent; Hemerly, Adriana S; Ferreira, Paulo C G

    2017-12-20

    Studies have highlighted the importance of non-coding RNA regulation in plant-microbe interaction. However, the roles of sugarcane microRNAs (miRNAs) in the regulation of disease responses have not been investigated. Firstly, we screened the sRNA transcriptome of sugarcane infected with Acidovorax avenae . Conserved and novel miRNAs were identified. Additionally, small interfering RNAs (siRNAs) were aligned to differentially expressed sequences from the sugarcane transcriptome. Interestingly, many siRNAs aligned to a transcript encoding a copper-transporter gene whose expression was induced in the presence of A. avenae , while the siRNAs were repressed in the presence of A. avenae . Moreover, a long intergenic non-coding RNA was identified as a potential target or decoy of miR408. To extend the bioinformatics analysis, we carried out independent inoculations and the expression patterns of six miRNAs were validated by quantitative reverse transcription-PCR (qRT-PCR). Among these miRNAs, miR408-a copper-microRNA-was downregulated. The cleavage of a putative miR408 target, a laccase, was confirmed by a modified 5'RACE (rapid amplification of cDNA ends) assay. MiR408 was also downregulated in samples infected with other pathogens, but it was upregulated in the presence of a beneficial diazotrophic bacteria. Our results suggest that regulation by miR408 is important in sugarcane sensing whether microorganisms are either pathogenic or beneficial, triggering specific miRNA-mediated regulatory mechanisms accordingly.

  9. Roles of Non-Coding RNA in Sugarcane-Microbe Interaction

    Science.gov (United States)

    Grativol, Clícia; Motta, Mariana R.; Ballesteros, Helkin G. F.; Peixoto, Barbara; Vieira, Lucas M.; Walter, Maria Emilia; de Armas, Elvismary M.; Entenza, Júlio O. P.; Lifschitz, Sergio; Farinelli, Laurent; Hemerly, Adriana S.

    2017-01-01

    Studies have highlighted the importance of non-coding RNA regulation in plant-microbe interaction. However, the roles of sugarcane microRNAs (miRNAs) in the regulation of disease responses have not been investigated. Firstly, we screened the sRNA transcriptome of sugarcane infected with Acidovorax avenae. Conserved and novel miRNAs were identified. Additionally, small interfering RNAs (siRNAs) were aligned to differentially expressed sequences from the sugarcane transcriptome. Interestingly, many siRNAs aligned to a transcript encoding a copper-transporter gene whose expression was induced in the presence of A. avenae, while the siRNAs were repressed in the presence of A. avenae. Moreover, a long intergenic non-coding RNA was identified as a potential target or decoy of miR408. To extend the bioinformatics analysis, we carried out independent inoculations and the expression patterns of six miRNAs were validated by quantitative reverse transcription-PCR (qRT-PCR). Among these miRNAs, miR408—a copper-microRNA—was downregulated. The cleavage of a putative miR408 target, a laccase, was confirmed by a modified 5′RACE (rapid amplification of cDNA ends) assay. MiR408 was also downregulated in samples infected with other pathogens, but it was upregulated in the presence of a beneficial diazotrophic bacteria. Our results suggest that regulation by miR408 is important in sugarcane sensing whether microorganisms are either pathogenic or beneficial, triggering specific miRNA-mediated regulatory mechanisms accordingly. PMID:29657296

  10. Roles of Non-Coding RNA in Sugarcane-Microbe Interaction

    Directory of Open Access Journals (Sweden)

    Flávia Thiebaut

    2017-12-01

    Full Text Available Studies have highlighted the importance of non-coding RNA regulation in plant-microbe interaction. However, the roles of sugarcane microRNAs (miRNAs in the regulation of disease responses have not been investigated. Firstly, we screened the sRNA transcriptome of sugarcane infected with Acidovorax avenae. Conserved and novel miRNAs were identified. Additionally, small interfering RNAs (siRNAs were aligned to differentially expressed sequences from the sugarcane transcriptome. Interestingly, many siRNAs aligned to a transcript encoding a copper-transporter gene whose expression was induced in the presence of A. avenae, while the siRNAs were repressed in the presence of A. avenae. Moreover, a long intergenic non-coding RNA was identified as a potential target or decoy of miR408. To extend the bioinformatics analysis, we carried out independent inoculations and the expression patterns of six miRNAs were validated by quantitative reverse transcription-PCR (qRT-PCR. Among these miRNAs, miR408—a copper-microRNA—was downregulated. The cleavage of a putative miR408 target, a laccase, was confirmed by a modified 5′RACE (rapid amplification of cDNA ends assay. MiR408 was also downregulated in samples infected with other pathogens, but it was upregulated in the presence of a beneficial diazotrophic bacteria. Our results suggest that regulation by miR408 is important in sugarcane sensing whether microorganisms are either pathogenic or beneficial, triggering specific miRNA-mediated regulatory mechanisms accordingly.

  11. The Non-Specific Binding of Fluorescent-Labeled MiRNAs on Cell Surface by Hydrophobic Interaction.

    Science.gov (United States)

    Lu, Ting; Lin, Zongwei; Ren, Jianwei; Yao, Peng; Wang, Xiaowei; Wang, Zhe; Zhang, Qunye

    2016-01-01

    MicroRNAs are small noncoding RNAs about 22 nt long that play key roles in almost all biological processes and diseases. The fluorescent labeling and lipofection are two common methods for changing the levels and locating the position of cellular miRNAs. Despite many studies about the mechanism of DNA/RNA lipofection, little is known about the characteristics, mechanisms and specificity of lipofection of fluorescent-labeled miRNAs. Therefore, miRNAs labeled with different fluorescent dyes were transfected into adherent and suspension cells using lipofection reagent. Then, the non-specific binding and its mechanism were investigated by flow cytometer and laser confocal microscopy. The results showed that miRNAs labeled with Cy5 (cyanine fluorescent dye) could firmly bind to the surface of adherent cells (Hela) and suspended cells (K562) even without lipofection reagent. The binding of miRNAs labeled with FAM (carboxyl fluorescein) to K562 cells was obvious, but it was not significant in Hela cells. After lipofectamine reagent was added, most of the fluorescently labeled miRNAs binding to the surface of Hela cells were transfected into intra-cell because of the high transfection efficiency, however, most of them were still binding to the surface of K562 cells. Moreover, the high-salt buffer which could destroy the electrostatic interactions did not affect the above-mentioned non-specific binding, but the organic solvent which could destroy the hydrophobic interactions eliminated it. These results implied that the fluorescent-labeled miRNAs could non-specifically bind to the cell surface by hydrophobic interaction. It would lead to significant errors in the estimation of transfection efficiency only according to the cellular fluorescence intensity. Therefore, other methods to evaluate the transfection efficiency and more appropriate fluorescent dyes should be used according to the cell types for the accuracy of results.

  12. The Non-Specific Binding of Fluorescent-Labeled MiRNAs on Cell Surface by Hydrophobic Interaction.

    Directory of Open Access Journals (Sweden)

    Ting Lu

    Full Text Available MicroRNAs are small noncoding RNAs about 22 nt long that play key roles in almost all biological processes and diseases. The fluorescent labeling and lipofection are two common methods for changing the levels and locating the position of cellular miRNAs. Despite many studies about the mechanism of DNA/RNA lipofection, little is known about the characteristics, mechanisms and specificity of lipofection of fluorescent-labeled miRNAs.Therefore, miRNAs labeled with different fluorescent dyes were transfected into adherent and suspension cells using lipofection reagent. Then, the non-specific binding and its mechanism were investigated by flow cytometer and laser confocal microscopy. The results showed that miRNAs labeled with Cy5 (cyanine fluorescent dye could firmly bind to the surface of adherent cells (Hela and suspended cells (K562 even without lipofection reagent. The binding of miRNAs labeled with FAM (carboxyl fluorescein to K562 cells was obvious, but it was not significant in Hela cells. After lipofectamine reagent was added, most of the fluorescently labeled miRNAs binding to the surface of Hela cells were transfected into intra-cell because of the high transfection efficiency, however, most of them were still binding to the surface of K562 cells. Moreover, the high-salt buffer which could destroy the electrostatic interactions did not affect the above-mentioned non-specific binding, but the organic solvent which could destroy the hydrophobic interactions eliminated it.These results implied that the fluorescent-labeled miRNAs could non-specifically bind to the cell surface by hydrophobic interaction. It would lead to significant errors in the estimation of transfection efficiency only according to the cellular fluorescence intensity. Therefore, other methods to evaluate the transfection efficiency and more appropriate fluorescent dyes should be used according to the cell types for the accuracy of results.

  13. CPT non-invariance and weak interactions

    International Nuclear Information System (INIS)

    Hsu, J.P.

    1973-01-01

    In this talk, I will describe a possible violation of CPT invariance in the domain of weak interactions. One can construct a model of weak interactions which, in order to be consistent with all experimental data, must violate CPT maximally. The model predicts many specific results for decay processes which could be tested in the planned neutral hyperon beam or neutrino beam at NAL. The motivations and the physical idea in the model are explained and the implications of the model are discussed. (U.S.)

  14. Parental care in Tundra Swans during the pre-fledgling period

    Science.gov (United States)

    Earnst, Susan L.

    2002-01-01

    Among studies that have quantified the care of precocial young, few have investigated forms of parental care other than vigilance. During the pre-fledging period, Tundra Swan (Cygnus columbianus columbianus) parents provided simultaneous biparental care by foraging near each other and their cygnets, and cygnets spent more time foraging during bouts in which both parents were foraging nearby than when only one parent was foraging nearby. Parents spent nearly twice as much foraging time on land than did non-parents, a habitat in which cygnets foraged more intensely than parents (i.e., spent more time foraging during foraging bouts) and could graze on protein-rich sedges rather than use more difficult below-water foraging methods. Parents also spent more than twice as much time being vigilant and more than three times as much time defending their territory than non-parents, behaviors that presumably benefited cygents by decreasing predation risk and indirect foraging competition, respectively. Parents therefore incurred the costs of foraging less intensely during foraging bouts, spending more time interacting, more time in vigilance, and less time sleeping/preening than non-parents.

  15. A Comparison of the Interactive Play Behaviours between Children with Albinism and Their Siblings and Children without Albinism and Their Non-Albino Siblings

    Science.gov (United States)

    Javangwe, Gwatirera; Mukondyo, Rachel Z.

    2012-01-01

    The study explored the nature of the interactive play behaviours of children with albinism and children without albinism and compared the interactive behaviours of both children with albinism and children without albinism. Naturalistic observations were conducted during periods of free play, using the interactive play behaviour checklist aided by…

  16. Some Analytical Properties of the Model for Stochastic Evolutionary Games in Finite Populations with Non-uniform Interaction Rate

    International Nuclear Information System (INIS)

    Quan Ji; Wang Xianjia

    2013-01-01

    Traditional evolutionary games assume uniform interaction rate, which means that the rate at which individuals meet and interact is independent of their strategies. But in some systems, especially biological systems, the players interact with each other discriminately. Taylor and Nowak (2006) were the first to establish the corresponding non-uniform interaction rate model by allowing the interaction rates to depend on strategies. Their model is based on replicator dynamics which assumes an infinite size population. But in reality, the number of individuals in the population is always finite, and there will be some random interference in the individuals' strategy selection process. Therefore, it is more practical to establish the corresponding stochastic evolutionary model in finite populations. In fact, the analysis of evolutionary games in a finite size population is more difficult. Just as Taylor and Nowak said in the outlook section of their paper, ''The analysis of non-uniform interaction rates should be extended to stochastic game dynamics of finite populations''. In this paper, we are exactly doing this work. We extend Taylor and Nowak's model from infinite to finite case, especially focusing on the infiuence of non-uniform connection characteristics on the evolutionary stable state of the system. We model the strategy evolutionary process of the population by a continuous ergodic Markov process. Based on the limit distribution of the process, we can give the evolutionary stable state of the system. We make a complete classification of the symmetric 2 × 2 games. For each case game, the corresponding limit distribution of the Markov-based process is given when noise intensity is small enough. In contrast with most literatures in evolutionary games using the simulation method, all our results obtained are analytical. Especially, in the dominant-case game, coexistence of the two strategies may become evolutionary stable states in our model. This result can be

  17. Two supramolecular complexes based on polyoxometalates and Co-EDTA units via covalent connection or non-covalent interaction

    Energy Technology Data Exchange (ETDEWEB)

    Teng, Chunlin; Xiao, Hanxi [Key Laboratory of Theoretical Organic Chemistry and Functional Molecule for Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201 (China); Cai, Qing [Chemistry Department, City University of New York, New York, NY 10016 (United States); Tang, Jianting; Cai, Tiejun [Key Laboratory of Theoretical Organic Chemistry and Functional Molecule for Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201 (China); Deng, Qian, E-mail: dengqian10502@163.com [Key Laboratory of Theoretical Organic Chemistry and Functional Molecule for Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201 (China)

    2016-11-15

    Two new 3D network organic-inorganic hybrid supramolecular complexes ([Na{sub 6}(CoEDTA){sub 2}(H{sub 2}O){sub 13}]·(H{sub 2}SiW{sub 12}O{sub 40})·xH{sub 2}O)n (1) and [CoH{sub 4}EDTA(H{sub 2}O)]{sub 2}(SiW{sub 12}O{sub 40})·15H{sub 2}O (2) (H{sub 4}EDTA=Ethylenediamine tetraacetic acid) have been successfully synthesized by solution method, and characterized by infrared spectrum (IR), thermogravimetric-differential thermal analysis (TG-DTA), cyclic voltammetry (CV) and single{sup −}crystal X-ray diffraction (XRD). Both of the complexes are the supramolecules, but with different liking mode, they are two representative models of supramolecule. complex (1) is a 3D infinite network supramolecular coordination polymer with a rare multi-metal sturcture of sodium-cobalt-containing, which is mainly linked through coordinate-covalent bonds. While complex (2) is normal supramolecule, which linked by non-covalent interactions, such as H-bonding interaction, electrostatic interaction and van der waals force. Both of complex (1) and (2) exhibit good catalytic activities for catalytic oxidation of methanol, when the initial concentration of methanol is 3.0 g m{sup −3}, flow rate is 10 mL min{sup −1}, and the quality of catalyst is 0.2 g, for complex (1) and complex (2) the maximum elimination rates of methanol are 85% (150 °C) and 92% (120 °C), respectively. - Graphical abstract: Two new organic-inorganic hybrid supramolecular complexes based on Co-EDTA, and Keggin polyanions have been successfully synthesized with different pH value by solution method. They are attributed to two representative models of supramolecule. Complex(1) is an infinite coordination polymer with a rare multi-metal sturcture of sodium-cobalt-containing, which is mainly linked through covalent bonds. Complex (2) is a normal supramolecule, which linked by non-covalent interactions of H-bonding interaction, electrostatic interaction and van der waals force. - Highlights: • Two supramolecules

  18. Interactions of neurotoxins with non-NMDA glutamate receptors: an autoradiographic study

    International Nuclear Information System (INIS)

    Kuenig, G.; Niedermeyer, B.; Krause, F.; Hartmann, J.; Deckert, J.; Heinsen, H.; Beckmann, H.; Riederer, P.; Ransmayr, G.

    1994-01-01

    Neurotoxic substances are discussed to cause neurode-generation by acting as excitotoxins on glutamate receptors. We investigated the properties of L-beta-oxalyl-amino-alanine (L-BOAA) and 3,4,6-trihydroxyphenlyalanine (6-OH-Dopa) at the alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) glutamate receptor and that of L-BOAA and domoic acid at the kainate glutamate receptor in human hippocampus. (3 H)AMPA binding in hippocampal subfields was inhibited by L-BOAA and 6-OH-Dopa with mean IC50-values in the low micromolar range. (3H)Kainate binding was inhibited by L-BOAA with similar potency as (3H)AMPA binding and by domoic acid with mean IC50-values in the low nanomolar range. These results support the notion that symptoms like anterograde amnesia and epileptic seizures seen in domoic acid intoxication and limbic symptoms, e.g. cognitive and mood impairment observed in neurolathyrism may be caused by excitotoxic action on non-NMDA receptors. The potent interaction of 6-OH-Dopa with the AMPA-receptor may point to a possible dopaminergic-glutamatergic interaction in the development of neurodegenerative diseases like Parkinson's and Huntington's disease. (author)

  19. The Interaction between Real Options and Financial Hedging: An Empirical Study of Danish Non-Financial Companies

    DEFF Research Database (Denmark)

    Aabo, Tom

    The interaction between real options and financial hedging is analyzed empirically. A majority of Danish non-financial companies either (1) chooses at times not to hedge an exchange rate operating exposure financially due to the possibility of the company to react to changes in exchange rates...

  20. Non-Abelian parafermions in time-reversal-invariant interacting helical systems

    Science.gov (United States)

    Orth, Christoph P.; Tiwari, Rakesh P.; Meng, Tobias; Schmidt, Thomas L.

    2015-02-01

    The interplay between bulk spin-orbit coupling and electron-electron interactions produces umklapp scattering in the helical edge states of a two-dimensional topological insulator. If the chemical potential is at the Dirac point, umklapp scattering can open a gap in the edge state spectrum even if the system is time-reversal invariant. We determine the zero-energy bound states at the interfaces between a section of a helical liquid which is gapped out by the superconducting proximity effect and a section gapped out by umklapp scattering. We show that these interfaces pin charges which are multiples of e /2 , giving rise to a Josephson current with 8 π periodicity. Moreover, the bound states, which are protected by time-reversal symmetry, are fourfold degenerate and can be described as Z4 parafermions. We determine their braiding statistics and show how braiding can be implemented in topological insulator systems.

  1. Damping characteristic identification of non-linear soil-structural system interaction by phase resonance

    International Nuclear Information System (INIS)

    Poterasu, V.F.

    1984-01-01

    It is presented a method and the phase resonance for damping characteristic identification of non-linear soil-structural interaction. The algorithm can be applied in case of any, not necessarily, damping characteristic of the system examined. For the identification, the system is harmonically excited and are considered the super-harmonic amplitudes for odd and even powers of the x. The response of shear beam system for different levels of base excitation and for different locations of the load is considered. (Author) [pt

  2. SLAVIC LITERATURES IN DALMATIAN PERIODICALS IN THE PERIOD OF CROATIAN MODERNISM

    Directory of Open Access Journals (Sweden)

    Robert Bacalja

    2010-01-01

    Full Text Available The paper analyzes translations and mediatorial articles from the Slavic literature published in Dalmatian newspapers and periodicals which contribute most to mediation during the period of Croatian Modernism. While periodicals in Dalmatia traditionally mediates from the Roman literature, especially from the Italian, in the examined corpus can be seen the remarkable reception of Slavic literature, particularly Russian.. The paradigm of the most recognized culture and literature in non Slavic world is desirable identity basis of the Croatian literature as a part of a large Slavic stem from romanticism to modernism. Mediation of Slavic literatures is examined on the corpus of newspapers and periodicals published in Dubrovnik, Split and Zadar (Crvena Hrvatska, Srđ, Sloboda, Jedinstvo/Novo jedinstvo, Novi vijek, Narodni list, Smotra dalmatinska, Iskra, Glasnik Matice dalmatinske, Lovor, etc..

  3. Source mechanisms of persistent shallow earthquakes during eruptive and non-eruptive periods between 1981 and 2011 at Mount St. Helens, Washington

    Science.gov (United States)

    Lehto, Heather L.; Roman, Diana C.; Moran, Seth C.

    2013-01-01

    Shallow seismicity between 0 and 3-km depth has persisted at Mount St. Helens, Washington (MSH) during both eruptive and non-eruptive periods for at least the past thirty years. In this study we investigate the source mechanisms of shallow volcano-tectonic (VT) earthquakes at MSH by calculating high-quality hypocenter locations and fault plane solutions (FPS) for all VT events recorded during two eruptive periods (1981–1986 and 2004–2008) and two non-eruptive periods (1987–2004 and 2008–2011). FPS show a mixture of normal, reverse, and strike-slip faulting during all periods, with a sharp increase in strike-slip faulting observed in 1987–1997 and an increase in normal faulting in 1998–2004. FPS P-axis orientations show a ~ 90° rotation with respect to regional σ1 (N23°E) during 1981–1986 and 2004–2008, bimodal orientations (~ N-S and ~ E-W) during 1987–2004, and bimodal orientations at ~ N-E and ~ S-W from 2008–2011. We interpret these orientations to likely be due to pressurization accompanying the shallow intrusion and subsequent eruption of magma as domes during 1981–1986 and 2004–2008 and the buildup of pore pressure beneath a seismogenic volume (located at 0–1 km) with a smaller component due to the buildup of tectonic forces during 1987–2004 and 2008–2011.

  4. Cross-sectional associations between daily rest periods during weekdays and psychological distress, non-restorative sleep, fatigue, and work performance among information technology workers.

    Science.gov (United States)

    Tsuchiya, Masao; Takahashi, Masaya; Miki, Keiichi; Kubo, Tomohide; Izawa, Shuhei

    2017-04-07

    A daily rest period (DRP; rest taken from daily work during a 24 h period), is essential to work recovery. This study examined DRPs' distribution and association with health outcomes among information technology workers recruited from an internet panel (N=1,811). Participants completed a web questionnaire examining psychological distress as a primary outcome, along with non-restorative sleep, fatigue (stress reaction), and work performance. Logistic regression analysis showed elevated psychological distress when DRP was working and commuting hours. After the above adjustment, similar associations were found with non-restorative sleep and fatigue, but not work performance, when DRP was <12 h. These findings constitute the first analysis of a dose-response relationship between DRP and subjective health outcomes among white-collar workers.

  5. Probing the Selectivity and Protein•Protein Interactions of a Non-Reducing Fungal Polyketide Synthase Using Mechanism-Based Crosslinkers

    Science.gov (United States)

    Bruegger, Joel; Haushalter, Bob; Vagstad, Anna; Shakya, Gaurav; Mih, Nathan; Townsend, Craig A.; Burkart, Michael D.; Tsai, Shiou-Chuan

    2013-01-01

    SUMMARY Protein•protein interactions, which often involve interactions between an acyl carrier protein (ACP) and its partner enzymes, are important for coordinating polyketide biosynthesis. However, the nature of such interactions is not well understood, especially in the fungal non-reducing polyketide synthases (NR-PKSs) that biosynthesize toxic and pharmaceutically important polyketides. Here, we employ a mechanism-based crosslinker to successfully probe ACP and ketosynthase (KS) domain interactions in NR-PKSs. We found that crosslinking efficiency is closely correlated with the strength of ACP•KS interactions, and that KS demonstrates strong starter unit selectivity. We further identified positively charged surface residues by KS mutagenesis, which mediate key interactions with the negatively-charged ACP surface. Such complementary/matching contact pairs can serve as “adapter surfaces” for future efforts to generate new polyketides using NR-PKSs. PMID:23993461

  6. Diet and human mobility from the lapita to the early historic period on Uripiv island, Northeast Malakula, Vanuatu.

    Directory of Open Access Journals (Sweden)

    Rebecca Kinaston

    Full Text Available Vanuatu was first settled ca. 3000 years ago by populations associated with the Lapita culture. Models of diet, subsistence practices, and human interaction for the Lapita and subsequent occupation periods have been developed mainly using the available archaeological and paleoenvironmental data. We test these models using stable (carbon, nitrogen, and sulfur and radiogenic (strontium isotopes to assess the diet and childhood residency of past communities that lived on the small (<1 km2 island of Uripiv, located off the northeast coast of Malakula, Vanuatu. The burials are from the initial Lapita occupation of the island (ca. 2800-2600 BP, the subsequent later Lapita (LL, ca. 2600-2500 BP and post-Lapita (PL, ca. 2500-2000 BP occupations, in addition to a late prehistoric/historic (LPH, ca. 300-150 BP occupation period. The human stable isotope results indicate a progressively more terrestrial diet over time, which supports the archaeological model of an intensification of horticultural and arboricultural systems as local resources were depleted, populations grew, and cultural situations changed. Pig diets were similar and included marine foods during the Lapita and PL periods but were highly terrestrial during the LPH period. This dietary pattern indicates that there was little variation in animal husbandry methods during the first 800 years of prehistory; however, there was a subsequent change as animal diets became more controlled in the LPH period. After comparison with the local bioavailable 87Sr/86Sr baseline, all of the Lapita and LPH individuals appeared to be 'local', but three of the PL individuals were identified as "non-local." We suggest that these "non-locals" moved to the island after infancy or childhood from one of the larger islands, supporting the model of a high level of regional interaction during the post-Lapita period.

  7. Alternans by non-monotonic conduction velocity restitution, bistability and memory

    International Nuclear Information System (INIS)

    Kim, Tae Yun; Hong, Jin Hee; Heo, Ryoun; Lee, Kyoung J

    2013-01-01

    Conduction velocity (CV) restitution is a key property that characterizes any medium supporting traveling waves. It reflects not only the dynamics of the individual constituents but also the coupling mechanism that mediates their interaction. Recent studies have suggested that cardiac tissues, which have a non-monotonic CV-restitution property, can support alternans, a period-2 oscillatory response of periodically paced cardiac tissue. This study finds that single-hump, non-monotonic, CV-restitution curves are a common feature of in vitro cultures of rat cardiac cells. We also find that the Fenton–Karma model, one of the well-established mathematical models of cardiac tissue, supports a very similar non-monotonic CV restitution in a physiologically relevant parameter regime. Surprisingly, the mathematical model as well as the cell cultures support bistability and show cardiac memory that tends to work against the generation of an alternans. Bistability was realized by adopting two different stimulation protocols, ‘S1S2’, which produces a period-1 wave train, and ‘alternans-pacing’, which favors a concordant alternans. Thus, we conclude that the single-hump non-monotonicity in the CV-restitution curve is not sufficient to guarantee a cardiac alternans, since cardiac memory interferes and the way the system is paced matters. (paper)

  8. Transcriptomic profiling of interacting nasal staphylococci species reveals global changes in gene and non-coding RNA expression

    DEFF Research Database (Denmark)

    Hermansen, Grith Miriam Maigaard; Sazinas, Pavelas; Kofod, Ditte

    2018-01-01

    Interspecies interactions between bacterial pathogens and the commensal microbiota can influence disease outcome. In the nasal cavities, Staphylococcus epidermidis has been shown to be a determining factor for Staphylococcus aureus colonization and biofilm formation. However, the interaction...... between S. epidermidis and S. aureus has mainly been described by phenotypic analysis, and little is known about how this interaction modulates gene expression.This study aimed to determine the interactome of nasal S. aureus and S. epidermidis isolates to understand the molecular effect of interaction...... also identified putative non-coding RNAs (ncRNAs) and, interestingly, detected a putative ncRNA transcribed antisense to esp, the serine protease of S. epidermidis, that has previously been shown to inhibit nasal colonization of S. aureus. In our study, the gene encoding Esp and the antisense nc...

  9. FCJ-132 Towards a Performative Aesthetics of Interactivity

    Directory of Open Access Journals (Sweden)

    Simon Penny

    2011-12-01

    Full Text Available This paper places contemporary modalities of digital interaction in an historical context of sixty years of intersections between technological development and artistic experimentation. Specific technological developments are identified as context-defining historical markers and specific works are discussed as exemplars of significant milestones in the engineering and the aesthetics of interaction. The shortage of theorisation of non-instrumental interaction is lamented. The process of naturalisation to increasingly sophisticated digital tools and appliances in the current period of ubiquitous computing is noted. A number of theoretical issues are drawn out and discussed in terms of cognitive and sensorimotor dynamics. Woven through the discussion is the proposal that a synthesis of performance theory and neuro-cognitive studies might provide a basis for a performative ontology around which an aesthetics of interaction might be constructed. As the paper progresses a theoretical framework for an ontologically performative aesthetics of interaction and ubiquity is formulated.

  10. Soil-Structure Interaction for Non-Slender, Large-Diameter Offshore Monopiles

    DEFF Research Database (Denmark)

    Sørensen, Søren Peder Hyldal

    Offshore wind power is a domestic, sustainable and largely untapped energy resource. Today, the modern offshore wind turbine offers competitive production prices compared to other sources of renewable energy. Therefore, it is a key technology in breaking the dependence on fossil fuels...... and in achieving the energy and climate goals of the future. For offshore wind turbines, the costs of foundation typically constitute 20-30% of the total costs. Hence, improved methods for the design of foundations for offshore wind turbines can increase the competitiveness of offshore wind energy significantly....... The monopile foundation concept has been employed as the foundation for the majority of the currently installed offshore wind turbines. Therefore, this PhD thesis concerns the soil-pile interaction for non-slender, large-diameter offshore piles. A combination of numerical and physical modelling has been...

  11. Interactions between chemical and non-chemical stressors and inherent characteristics to elucidate children’s mental health disparities

    Science.gov (United States)

    Children may be more vulnerable to the combined interactions of chemical and non-chemical stressors from their built, natural, and social environments when compared to adults. When children are exposed to cigarette smoke, bisphenol A (BPA), or organophosphate pesticides, they are...

  12. “ Blaming, shaming, humiliation”: Stigmatising medical interactions among people with non-epileptic seizures

    Science.gov (United States)

    Robson, Catherine; Lian, Olaug S.

    2017-01-01

    Background: People with non-epileptic seizures (NES) describe challenging relationships with health professionals, and explain negative interactions as common and expected. Despite these difficulties, little is known about how people with NES experience difficult healthcare encounters. Methods: Using a thematic discourse analysis approach, we analysed the free-text survey responses of 135 people with NES and asked: what kind of challenges do people living with this condition encounter when interacting with health professionals, and how do they experience the consequences of difficult interactions? We explore their experiences by interpreting the latent meaning of participants’ texts from a social-constructionist perspective on health and illness. Results: The overarching narrative depicts a fundamental breakdown in patient-provider relationships. According to our data, the negative experiences of study participants emerge from more than practitioners’ lack of awareness of NES and access to information about the condition - to the extent that it is available. In examining the challenges people with NES encounter when interacting with health professionals, their main experiences centre on blame and humiliation. When exploring their experiences, theories of stigma serve as a useful theoretical framework. Conclusions: Normative judgements arising from psychogenic understandings of NES are stigmatising and restrict professional displays of respectful (patient-centred) care. Those with the condition depict being negatively stereotyped, illegitimated and held morally culpable by health professionals. Perceived to lack medical, moral and credible status, participants describe practitioners who treat them with disrespect, and some recount conduct that defies all ethical and professional obligations and standards. These encounters can have wide-ranging adverse consequences for patients: emotionally, physically, and for their future healthcare. The quality of healthcare

  13. Periodic and chaotic oscillations in a tumor and immune system interaction model with three delays

    International Nuclear Information System (INIS)

    Bi, Ping; Ruan, Shigui; Zhang, Xinan

    2014-01-01

    In this paper, a tumor and immune system interaction model consisted of two differential equations with three time delays is considered in which the delays describe the proliferation of tumor cells, the process of effector cells growth stimulated by tumor cells, and the differentiation of immune effector cells, respectively. Conditions for the asymptotic stability of equilibria and existence of Hopf bifurcations are obtained by analyzing the roots of a second degree exponential polynomial characteristic equation with delay dependent coefficients. It is shown that the positive equilibrium is asymptotically stable if all three delays are less than their corresponding critical values and Hopf bifurcations occur if any one of these delays passes through its critical value. Numerical simulations are carried out to illustrate the rich dynamical behavior of the model with different delay values including the existence of regular and irregular long periodic oscillations

  14. Non-perturbative effective interactions in the standard model

    CERN Document Server

    Arbuzov, Boris A

    2014-01-01

    This monograph is devoted to the nonperturbative dynamics in the Standard Model (SM), the basic theory of all, but gravity, fundamental interactions in nature. The Standard Model is devided into two parts: the Quantum chromodynamics (QCD) and the Electro-weak theory (EWT) are well-defined renormalizable theories in which the perturbation theory is valid. However, for the adequate description of the real physics nonperturbative effects are inevitable. This book describes how these nonperturbative effects may be obtained in the framework of spontaneous generation of effective interactions. The well-known example of such effective interaction is provided by the famous Nambu--Jona-Lasinio effective interaction. Also a spontaneous generation of this interaction in the framework of QCD is described and applied to the method for other effective interactions in QCD and EWT. The method is based on N.N. Bogoliubov conception of compensation equations. As a result we then describe the principle feathures of the Standard...

  15. NPR1 protein regulates pathogenic and symbiotic interactions between Rhizobium and legumes and non-legumes.

    Directory of Open Access Journals (Sweden)

    Smadar Peleg-Grossman

    Full Text Available BACKGROUND: Legumes are unique in their ability to establish symbiotic interaction with rhizobacteria from Rhizobium genus, which provide them with available nitrogen. Nodulation factors (NFs produced by Rhizobium initiate legume root hair deformation and curling that entrap the bacteria, and allow it to grow inside the plant. In contrast, legumes and non-legumes activate defense responses when inoculated with pathogenic bacteria. One major defense pathway is mediated by salicylic acid (SA. SA is sensed and transduced to downstream defense components by a redox-regulated protein called NPR1. METHODOLOGY/PRINCIPAL FINDINGS: We used Arabidopsis mutants in SA defense pathway to test the role of NPR1 in symbiotic interactions. Inoculation of Sinorhizobium meliloti or purified NF on Medicago truncatula or nim1/npr1 A. thaliana mutants induced root hair deformation and transcription of early and late nodulins. Application of S. meliloti or NF on M. truncatula or A. thaliana roots also induced a strong oxidative burst that lasted much longer than in plants inoculated with pathogenic or mutualistic bacteria. Transient overexpression of NPR1 in M. truncatula suppressed root hair curling, while inhibition of NPR1 expression by RNAi accelerated curling. CONCLUSIONS/SIGNIFICANCE: We show that, while NPR1 has a positive effect on pathogen resistance, it has a negative effect on symbiotic interactions, by inhibiting root hair deformation and nodulin expression. Our results also show that basic plant responses to Rhizobium inoculation are conserved in legumes and non-legumes.

  16. Core/Shell Conjugated Polymer/Quantum Dot Composite Nanofibers through Orthogonal Non-Covalent Interactions

    Directory of Open Access Journals (Sweden)

    Brad W. Watson

    2016-11-01

    Full Text Available Nanostructuring organic polymers and organic/inorganic hybrid materials and controlling blend morphologies at the molecular level are the prerequisites for modern electronic devices including biological sensors, light emitting diodes, memory devices and solar cells. To achieve all-around high performance, multiple organic and inorganic entities, each designed for specific functions, are commonly incorporated into a single device. Accurate arrangement of these components is a crucial goal in order to achieve the overall synergistic effects. We describe here a facile methodology of nanostructuring conjugated polymers and inorganic quantum dots into well-ordered core/shell composite nanofibers through cooperation of several orthogonal non-covalent interactions including conjugated polymer crystallization, block copolymer self-assembly and coordination interactions. Our methods provide precise control on the spatial arrangements among the various building blocks that are otherwise incompatible with one another, and should find applications in modern organic electronic devices such as solar cells.

  17. Periodic subsystem density-functional theory

    International Nuclear Information System (INIS)

    Genova, Alessandro; Pavanello, Michele; Ceresoli, Davide

    2014-01-01

    By partitioning the electron density into subsystem contributions, the Frozen Density Embedding (FDE) formulation of subsystem Density Functional Theory (DFT) has recently emerged as a powerful tool for reducing the computational scaling of Kohn–Sham DFT. To date, however, FDE has been employed to molecular systems only. Periodic systems, such as metals, semiconductors, and other crystalline solids have been outside the applicability of FDE, mostly because of the lack of a periodic FDE implementation. To fill this gap, in this work we aim at extending FDE to treat subsystems of molecular and periodic character. This goal is achieved by a dual approach. On one side, the development of a theoretical framework for periodic subsystem DFT. On the other, the realization of the method into a parallel computer code. We find that periodic FDE is capable of reproducing total electron densities and (to a lesser extent) also interaction energies of molecular systems weakly interacting with metallic surfaces. In the pilot calculations considered, we find that FDE fails in those cases where there is appreciable density overlap between the subsystems. Conversely, we find FDE to be in semiquantitative agreement with Kohn–Sham DFT when the inter-subsystem density overlap is low. We also conclude that to make FDE a suitable method for describing molecular adsorption at surfaces, kinetic energy density functionals that go beyond the GGA level must be employed

  18. Periodic subsystem density-functional theory

    Science.gov (United States)

    Genova, Alessandro; Ceresoli, Davide; Pavanello, Michele

    2014-11-01

    By partitioning the electron density into subsystem contributions, the Frozen Density Embedding (FDE) formulation of subsystem Density Functional Theory (DFT) has recently emerged as a powerful tool for reducing the computational scaling of Kohn-Sham DFT. To date, however, FDE has been employed to molecular systems only. Periodic systems, such as metals, semiconductors, and other crystalline solids have been outside the applicability of FDE, mostly because of the lack of a periodic FDE implementation. To fill this gap, in this work we aim at extending FDE to treat subsystems of molecular and periodic character. This goal is achieved by a dual approach. On one side, the development of a theoretical framework for periodic subsystem DFT. On the other, the realization of the method into a parallel computer code. We find that periodic FDE is capable of reproducing total electron densities and (to a lesser extent) also interaction energies of molecular systems weakly interacting with metallic surfaces. In the pilot calculations considered, we find that FDE fails in those cases where there is appreciable density overlap between the subsystems. Conversely, we find FDE to be in semiquantitative agreement with Kohn-Sham DFT when the inter-subsystem density overlap is low. We also conclude that to make FDE a suitable method for describing molecular adsorption at surfaces, kinetic energy density functionals that go beyond the GGA level must be employed.

  19. The highest velocity and the shortest duration permitting attainment of VO2max during running

    Directory of Open Access Journals (Sweden)

    Tiago Turnes

    2015-02-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2015v17n2p226   The severe-intensity domain has important applications for the prescription of running training and the elaboration of experimental designs. The objectives of this study were: 1 to investigate the validity of a previously proposed model to estimate the shortest exercise duration (TLOW and the highest velocity (VHIGH at which VO2max is reached during running, and 2 to evaluate the effects of aerobic training status on these variables. Eight runners and eight physically active subjects performed several treadmill running exercise tests to fatigue in order to mathematically estimate and to experimentally determine TLOW and VHIGH. The relationship between the time to achieve VO2max and time to exhaustion (Tlim was used to estimate TLOW. VHIGH was estimated using the critical velocity model. VHIGH was assumed to be the highest velocity at which VO2 was equal to or higher than the average VO2max minus one standard deviation. TLOW was defined as Tlim associated with VHIGH. Runners presented better aerobic fitness and higher VHIGH (22.2 ± 1.9 km.h-1 than active subjects (20.0 ± 2.1 km.h-1. However, TLOW did not differ between groups (runners: 101 ± 39 s; active subjects: 100 ± 35 s. TLOW and VHIGH were not well estimated by the model proposed, with high coefficients of variation (> 6% and a low correlation coefficient (r<0.70, a fact reducing the validity of the model. It was concluded that aerobic training status positively affected only VHIGH. Furthermore, the model proposed presented low validity to estimate the upper boundary of the severe-intensity domain (i.e., VHIGH, irrespective of the subjects’ training status.

  20. Atomic Ensemble Effects and Non-Covalent Interactions at the Electrode–Electrolyte Interface

    Directory of Open Access Journals (Sweden)

    Angel Cuesta

    2016-09-01

    Full Text Available Cyanide-modified Pt(111 electrodes have been recently employed to study atomic ensemble effects in electrocatalysis. This work, which will be briefly reviewed, reveals that the smallest site required for methanol dehydrogenation and formic acid dehydration is composed of three contiguous Pt atoms. By blocking these trigonal sites, the specific adsorption of anions, such as sulfate and phosphate, can be inhibited, thus increasing the rate of oxygen reduction reaction by one order of magnitude or more. Moreover, alkali metal cations affect hydrogen adsorption on cyanide-modified Pt(111. This effect is attributed to the non-covalent interactions at the electrical double layer between specifically adsorbed anions or dipoles and the alkali metal cations. A systematic investigation is conducted on the effect of the concentration of alkali metal cations. Accordingly, a simple model that reproduces the experimental observations accurately and enables the understanding of the trends in the strength of the interaction between M+ and CNad when moving from Li+ to Cs+, as well as the deviations from the expected trends, is developed. This simple model can also explain the occurrence of super-Nernstian shifts of the equilibrium potential of interfacial proton-coupled electron transfers. Therefore, the model can be generally applied to explain quantitatively the effect of cations on the properties of the electrical double layer. The recently reported effects of alkali metal cations on several electrocatalytic reactions must be mediated by the interaction between these cations and chemisorbed species. As these interactions seem to be adequately and quantitatively described by our model, we expect the model to also be useful to describe, explain, and potentially exploit these effects.

  1. Non-perturbative effective interactions in the standard model

    Energy Technology Data Exchange (ETDEWEB)

    Arbuzov, Boris A. [Moscow Lomonosov State Univ. (Russian Federation). Skobeltsyn Inst. of Nuclear Physics

    2014-07-01

    This monograph is devoted to the nonperturbative dynamics in the Standard Model (SM), the basic theory of allfundamental interactions in natureexcept gravity. The Standard Model is divided into two parts: the quantum chromodynamics (QCD) and the electro-weak theory (EWT) are well-defined renormalizable theories in which the perturbation theory is valid. However, for the adequate description of the real physics nonperturbative effects are inevitable. This book describes how these nonperturbative effects may be obtained in the framework of spontaneous generation of effective interactions. The well-known example of such effective interaction is provided by the famous Nambu-Jona-Lasinio effective interaction. Also a spontaneous generation of this interaction in the framework of QCD is described and applied to the method for other effective interactions in QCD and EWT. The method is based on N.N. Bogolyubov's conception of compensation equations. As a result we then describe the principal features of the Standard Model, e.g. Higgs sector, and significant nonperturbative effects including recent results obtained at LHC and TEVATRON.

  2. Theory of Periodic Conjugate Heat Transfer

    CERN Document Server

    Zudin, Yuri B

    2012-01-01

    This book presents the theory of periodic conjugate heat transfer in a detailed way. The effects of thermophysical properties and geometry of a solid body on the commonly used and experimentally determined heat transfer coefficient are analytically presented from a general point of view. The main objective of the book is a simplified description of the interaction between a solid body and a fluid as a boundary value problem of the heat conduction equation for the solid body. At the body surface, the true heat transfer coefficient is composed of two parts: the true mean value resulting from the solution of the steady state heat transfer problem and a periodically variable part, the periodic time and length to describe the oscillatory hydrodynamic effects. The second edition is extended by (i) the analysis of stability boundaries in helium flow at supercritical conditions in a heated channel with respect to the interaction between a solid body and a fluid; (ii) a periodic model and a method of heat transfer sim...

  3. Rate of non-linearity in DMS aerosol-cloud-climate interactions

    Directory of Open Access Journals (Sweden)

    M. A. Thomas

    2011-11-01

    Full Text Available The degree of non-linearity in DMS-cloud-climate interactions is assessed using the ECHAM5-HAMMOZ model by taking into account end-to-end aerosol chemistry-cloud microphysics link. The evaluation is made over the Southern oceans in austral summer, a region of minimal anthropogenic influence. In this study, we compare the DMS-derived changes in the aerosol and cloud microphysical properties between a baseline simulation with the ocean DMS emissions from a prescribed climatology, and a scenario where the DMS emissions are doubled. Our results show that doubling the DMS emissions in the current climate results in a non-linear response in atmospheric DMS burden and subsequently, in SO2 and H2SO4 burdens due to inadequate OH oxidation. The aerosol optical depth increases by only ~20 % in the 30° S–75° S belt in the SH summer months. This increases the vertically integrated cloud droplet number concentrations (CDNC by 25 %. Since the vertically integrated liquid water vapor is constant in our model simulations, an increase in CDNC leads to a reduction in cloud droplet radius of 3.4 % over the Southern oceans in summer. The equivalent increase in cloud liquid water path is 10.7 %. The above changes in cloud microphysical properties result in a change in global annual mean radiative forcing at the TOA of −1.4 W m−2. The results suggest that the DMS-cloud microphysics link is highly non-linear. This has implications for future studies investigating the DMS-cloud climate feedbacks in a warming world and for studies evaluating geoengineering options to counteract warming by modulating low level marine clouds.

  4. Interaction between periodic in-service inspection requirements and design

    International Nuclear Information System (INIS)

    Prot, A.C.; Saglio, R.

    1979-03-01

    After reviewing the requirements specific of periodic In-Service Inspection related to safety problems, especially for the pressure vessels, and taking into account the experience gained with several PWR reactors, the authors show these requirements could lead to modify the primary circuit design

  5. Effects of non-covalent interactions with 5-O-caffeoylquinic acid (chlorogenic acid) on the heat denaturation and solubility of globular proteins

    NARCIS (Netherlands)

    Prigent, S.V.E.; Gruppen, H.; Visser, A.J.W.G.; Koningsveld, G.A. van; Jong, G.A.H. de; Voragen, A.G.J.

    2003-01-01

    The non-covalent interactions between the monomeric phenolic compound chlorogenic acid (5-CQA) and bovine serum albumin (BSA), lysozyme, and α-lactalbumin were characterized, and their effect on protein properties was examined. 5-CQA had a low affinity for all three proteins, and these interactions

  6. Assessing non-linear variation of temperature and precipitation for different growth periods of maize and their impacts on phenology in the Midwest of Jilin Province, China

    Science.gov (United States)

    Guo, Enliang; Zhang, Jiquan; Wang, Yongfang; Alu, Si; Wang, Rui; Li, Danjun; Ha, Si

    2018-05-01

    In the past two decades, the regional climate in China has undergone significant change, resulting in crop yield reduction and complete failure. The goal of this study is to detect the variation of temperature and precipitation for different growth periods of maize and assess their impact on phenology. The daily meteorological data in the Midwest of Jilin Province during 1960-2014 were used in the study. The ensemble empirical mode decomposition method was adopted to analyze the non-linear trend and fluctuation in temperature and precipitation, and the sensitivity of the length of the maize growth period to temperature and precipitation was analyzed by the wavelet cross-transformation method. The results show that the trends of temperature and precipitation change are non-linear for different growth periods of maize, and the average temperature in the sowing-jointing stage was different from that in the other growth stages, showing a slight decrease trend, while the variation amplitude of maximum temperature is smaller than that of the minimum temperature. This indicates that the temperature difference between day and night shows a gradually decreasing trend. Precipitation in the growth period also showed a decreasing non-linear trend, while the inter-annual variability with period of quasi-3-year and quasi-6-year dominated the variation of temperature and precipitation. The whole growth period was shortened by 10.7 days, and the sowing date was advanced by approximately 11 days. We also found that there was a significant resonance period among temperature, precipitation, and phenology. Overall, a negative correlation between phenology and temperature is evident, while a positive correlation with precipitation is exhibited. The results illustrate that the climate suitability for maize has reduced over the past decades.

  7. Dual-component model of respiratory motion based on the periodic autoregressive moving average (periodic ARMA) method

    International Nuclear Information System (INIS)

    McCall, K C; Jeraj, R

    2007-01-01

    A new approach to the problem of modelling and predicting respiration motion has been implemented. This is a dual-component model, which describes the respiration motion as a non-periodic time series superimposed onto a periodic waveform. A periodic autoregressive moving average algorithm has been used to define a mathematical model of the periodic and non-periodic components of the respiration motion. The periodic components of the motion were found by projecting multiple inhale-exhale cycles onto a common subspace. The component of the respiration signal that is left after removing this periodicity is a partially autocorrelated time series and was modelled as an autoregressive moving average (ARMA) process. The accuracy of the periodic ARMA model with respect to fluctuation in amplitude and variation in length of cycles has been assessed. A respiration phantom was developed to simulate the inter-cycle variations seen in free-breathing and coached respiration patterns. At ±14% variability in cycle length and maximum amplitude of motion, the prediction errors were 4.8% of the total motion extent for a 0.5 s ahead prediction, and 9.4% at 1.0 s lag. The prediction errors increased to 11.6% at 0.5 s and 21.6% at 1.0 s when the respiration pattern had ±34% variations in both these parameters. Our results have shown that the accuracy of the periodic ARMA model is more strongly dependent on the variations in cycle length than the amplitude of the respiration cycles

  8. Modified holographic Ricci dark energy coupled to interacting dark matter and a non-interacting baryonic component

    Energy Technology Data Exchange (ETDEWEB)

    Chimento, Luis P.; Richarte, Martin G. [Universidad de Buenos Aires, IFIBA, CONICET, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina); Forte, Monica [Universidad de Buenos Aires, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina)

    2013-01-15

    We examine a Friedmann-Robertson-Walker universe filled with interacting dark matter, modified holographic Ricci dark energy (MHRDE), and a decoupled baryonic component. The estimations of the cosmic parameters with Hubble data lead to an age of the universe of 13.17 Gyr and show that the MHRDE is free from the cosmic-age problem at low redshift (0{<=}z{<=}2) in contrast to holographic Ricci dark energy (HRDE) case. We constrain the parameters with the Union2 data set and contrast with the Hubble data. We also study the behavior of dark energy at early times by taking into account the severe bounds found at recombination era and/or at big bang nucleosynthesis. The inclusion of a non-interacting baryonic matter forces that the amount of dark energy at z{sub t} {proportional_to} O(1) changes abruptly implying that {Omega} {sub x} (z {approx_equal}1100)=0.03, so the bounds reported by the forecast of Planck and CMBPol experiments are more favored for the MHRDE model than in the case of HRDE cutoff. For the former model, we also find that at high redshift the fraction of dark energy varies from 0.006 to 0.002, then the amount of {Omega} {sub x} at the big bang nucleosynthesis era does not disturb the observed helium abundance in the universe provided that the bound {Omega} {sub x} (z {approx_equal}10 {sup 10}) <0.21 is hold. (orig.)

  9. On the evolutionary status and pulsations of the recently discovered blue large-amplitude pulsators (BLAPs)

    Science.gov (United States)

    Romero, Alejandra D.; Córsico, A. H.; Althaus, L. G.; Pelisoli, I.; Kepler, S. O.

    2018-06-01

    The blue large-amplitude pulsators (BLAPs) constitute a new class of pulsating stars. They are hot stars with effective temperatures of ˜30 000 K and surface gravities of log g ˜ 4.9, that pulsate with periods in the range 20-40 min. Until now, their origin and evolutionary state, as well as the nature of their pulsations, were not been unveiled. In this paper, we propose that the BLAPs are the hot counterpart of the already known pulsating pre-extremely low mass (pre-ELM) white dwarf (WD) stars, that are He-core low-mass stars resulting from interacting binary evolution. Using fully evolutionary sequences, we show that the BLAPs are well represented by pre-ELM WD models with high effective temperature and stellar masses ˜0.34 M⊙. From the analysis of their pulsational properties, we find that the observed variabilities can be explained by high-order non-radial g-mode pulsations or, in the case of the shortest periods, also by low-order radial modes, including the fundamental radial mode. The theoretical modes with periods in the observed range are unstable due to the κ mechanism associated with the Z-bump in the opacity at log T ˜ 5.25.

  10. Improving a Complement-fixation Test for Equine Herpesvirus Type-1 by Pretreating Sera with Potassium Periodate to Reduce Non-specific Hemolysis

    Science.gov (United States)

    BANNAI, Hiroshi; NEMOTO, Manabu; TSUJIMURA, Koji; YAMANAKA, Takashi; KONDO, Takashi; MATSUMURA, Tomio

    2013-01-01

    Non-specific hemolysis has often been observed during complement-fixation (CF) tests for equine herpesvirus type-1 (EHV-1), even when the sera have virus-specific CF antibodies. This phenomenon has also been reported in CF tests for various infectious diseases of swine. We found that the sera from 22 of 85 field horses (25.9%) showed non-specific hemolysis during conventional CF testing for EHV-1. Because pretreatment of swine sera with potassium periodate (KIO4) improves the CF test for swine influenza, we applied this method to horse sera. As we expected, horse sera treated with KIO4 did not show non-specific hemolysis in the EHV-1 CF test, and precise determination of titers was achieved. PMID:24834005

  11. Lepton flavor violating non-standard interactions via light mediators

    Energy Technology Data Exchange (ETDEWEB)

    Farzan, Yasaman [School of physics, Institute for Research in Fundamental Sciences (IPM),P.O. Box 19395-5531, Tehran (Iran, Islamic Republic of); Shoemaker, Ian M. [Department of Physics, Department of Astronomy & Astrophysics,Center for Particle and Gravitational Astrophysics,The Pennsylvania State University, PA 16802 (United States)

    2016-07-07

    Non-Standard neutral current Interactions (NSIs) of neutrinos with matter can alter the pattern of neutrino oscillation due to the coherent forward scattering of neutrinos on the medium. This effect makes long-baseline neutrino experiments such as NOνA and DUNE a sensitive probe of beyond standard model (BSM) physics. We construct light mediator models that can give rise to both lepton flavor conserving as well as Lepton Flavor Violating (LFV) neutral current NSI. We outline the present phenomenological viability of these models and future prospects to test them. We predict a lower bound on Br(H→μτ) in terms of the parameters that can be measured by DUNE and NOνA, and show that the hint for H→μτ in current LHC data can be accommodated in our model. A large part of the parameter space of the model is already constrained by the bound on Br(τ→Z{sup ′}μ) and by the bounds on rare meson decays and can be in principle fully tested by improving these bounds.

  12. Construction of exchange-correlation functionals through interpolation between the non-interacting and the strong-correlation limit

    International Nuclear Information System (INIS)

    Zhou, Yongxi; Ernzerhof, Matthias; Bahmann, Hilke

    2015-01-01

    Drawing on the adiabatic connection of density functional theory, exchange-correlation functionals of Kohn-Sham density functional theory are constructed which interpolate between the extreme limits of the electron-electron interaction strength. The first limit is the non-interacting one, where there is only exchange. The second limit is the strong correlated one, characterized as the minimum of the electron-electron repulsion energy. The exchange-correlation energy in the strong-correlation limit is approximated through a model for the exchange-correlation hole that is referred to as nonlocal-radius model [L. O. Wagner and P. Gori-Giorgi, Phys. Rev. A 90, 052512 (2014)]. Using the non-interacting and strong-correlated extremes, various interpolation schemes are presented that yield new approximations to the adiabatic connection and thus to the exchange-correlation energy. Some of them rely on empiricism while others do not. Several of the proposed approximations yield the exact exchange-correlation energy for one-electron systems where local and semi-local approximations often fail badly. Other proposed approximations generalize existing global hybrids by using a fraction of the exchange-correlation energy in the strong-correlation limit to replace an equal fraction of the semi-local approximation to the exchange-correlation energy in the strong-correlation limit. The performance of the proposed approximations is evaluated for molecular atomization energies, total atomic energies, and ionization potentials

  13. Peculiarities of Stereotypes about Non-Verbal Communication and their Role in Cross-Cultural Interaction between Russian and Chinese Students

    Directory of Open Access Journals (Sweden)

    I A Novikova

    2012-12-01

    Full Text Available The article is devoted to the analysis of the peculiarities of the stereotypes about non-verbal communication, formed in Russian and Chinese cultures. The results of the experimental research of the role of ethnic auto- and heterostereotypes about non-verbal communication in cross-cultural interaction between Russian and Chinese students of the Peoples’ Friendship University of Russia are presented.

  14. CHARACTERISATION OF MULTIPHASE FLUID-STRUCTURE INTERACTION USING NON-INTRUSIVE OPTICAL TECHNIQUES

    Directory of Open Access Journals (Sweden)

    M. AL-ATABI

    2011-04-01

    Full Text Available The purpose of this study is to determine experimentally the effectiveness of passive drag reduction techniques (which involve adjusting surface geometry within a chaotic multiphase flow system. To quantify the intrusion and disturbance caused, a liquid-air blast atomiser continuously discharges within a test section of air at atmospheric pressure, with a circular cylinder placed 25 cylinder diameters (250 mm downstream of the nozzle. This cylinder is then replaced with other cylinders which have modified surface geometry. The data was obtained using Particle Image Velocimetry (PIV and determines the fluid motion resulting from spray structure interaction of a liquid spray with a circular cylinder. Subtraction of non intruded spray images from intruded spray images at the same locations, using the time averaged analysis allows the direct comparison of the amount of disturbance each geometric variant has on the spray. Using this data alongside velocity profiles time averaged trends were compared. Drag reduction from V-shaped grooves provides the greatest disturbance reduction. This is due to the reduced shear stress around its cross section and the addition of small liquid eddies within each V-groove creates a gliding surface. These features proved to be most effective when monitoring drag reduction in multiphase flow-structure interaction.

  15. Interaction of non-equilibrium phonons with electron-hole plasmas in germanium

    International Nuclear Information System (INIS)

    Kirch, S.J.

    1985-01-01

    This thesis presents results of experiments on the interaction of phonons and photo-excited electron-hole plasmas in Ge at low temperature. The first two studies involved the low-temperature fluid phase known as the electron-hole liquid (EHL). The third study involved a wider range of temperatures and includes the higher temperature electron-hole plasma (EHP). In the first experiment, superconducting tunnel junctions are used to produce quasi-monochromatic phonons, which propagate through the EHL. The magnitude of the absorption of these non-equilibrium phonons gives a direct measure of the coupling constant, the deformation potential. In the second experiment, the nonequilibrium phonons are generated by laser excitation of a metal film. An unusual sample geometry allows examination of the EHL-phonon interaction near the EHL excitation surface. This coupling is examined for both cw and pulsed EHL excitation. In the third experiment, the phonons are byproducts of the photo-excited carrier thermalization. The spatial, spectral and temporal dependence of the recombination luminescence is examined. A phonon wind force is observed to dominate the transport properties of the EHL and the EHP. These carriers are never observed to move faster than the phonon velocity even during the laser pulse

  16. A modified atmospheric non-hydrostatic model on low aspect ratio grids: part II

    Directory of Open Access Journals (Sweden)

    Wen-Yih Sun

    2013-06-01

    Full Text Available Sun et al. (2012 proposed a modified non-hydrostatic model (MNH, in which the left-hand side of the continuity equation is multiplied by a parameter δ (4≤δ≤16 in the article to suppress high-frequency acoustic waves. They showed that the MNH allows a longer time step than the original non-hydrostatic model (NH. The MNH is also more accurate and efficient than the horizontal explicit and vertical implicit scheme (HE–VI when the aspect ratio (Δx/Δz is small. In addition to multiplying a parameter δ, here we propose to add a smoothing on the right-hand side of the continuity equation in the MNH to damp shortest sound waves. Linear stability analysis and non-linear model simulations show that the MNH with smoothing (henceforth abbreviated as MNHS can use twice the time interval of the MNH while maintaining the same accuracy. The MNHS is also more accurate and efficient than HE–VI when the aspect ratio is small.

  17. Non-interactive and Reusable Non-malleable Commitment Schemes

    DEFF Research Database (Denmark)

    Damgård, Ivan Bjerre; Groth, Jens

    2003-01-01

    version based on the strong RSA assumption. For UC commitments, we show that existence of a UC commitment scheme in the CRS model (interactive or not) implies key exchange and - for a uniform reference string - even implies oblivious transfer. This indicates that UC commitment is a strictly stronger...... primitive than NM. Finally, we show that our strong RSA based construction can be used to improve the most efficient known UC commitment scheme so it can work with a CRS of size independent of the number of players, without loss of efficiency....

  18. Interaction between confined phonons and photons in periodic silicon resonators

    Science.gov (United States)

    Iskandar, A.; Gwiazda, A.; Younes, J.; Kazan, M.; Bruyant, A.; Tabbal, M.; Lerondel, G.

    2018-03-01

    In this paper, we demonstrate that phonons and photons of different momenta can be confined and interact with each other within the same nanostructure. The interaction between confined phonons and confined photons in silicon resonator arrays is observed by means of Raman scattering. The Raman spectra from large arrays of dielectric silicon resonators exhibited Raman enhancement accompanied with a downshift and broadening. The analysis of the Raman intensity and line shape using finite-difference time-domain simulations and a spatial correlation model demonstrated an interaction between photons confined in the resonators and phonons confined in highly defective regions prompted by the structuring process. It was shown that the Raman enhancement is due to collective lattice resonance inducing field confinement in the resonators, while the spectra downshift and broadening are signatures of the relaxation of the phonon wave vector due to phonon confinement in defective regions located in the surface layer of the Si resonators. We found that as the resonators increase in height and their shape becomes cylindrical, the amplitude of their coherent oscillation increases and hence their ability to confine the incoming electric field increases.

  19. Radiologist involvement is associated with reduced use of MRI in the acute period of low back pain in a non-elderly population

    International Nuclear Information System (INIS)

    Kumamaru, Kanako K.; Sano, Yukiko; Hori, Masaaki; Takamura, Tomohiro; Irie, Ryusuke; Suzuki, Michimasa; Hagiwara, Akifumi; Kamagata, Koji; Nakanishi, Atsushi; Aoki, Shigeki; Kumamaru, Hiraku

    2018-01-01

    To test the hypothesis that ''acute-period'' lumbar MRI in non-elderly patients with low back pain is less frequently performed at clinics/hospitals with greater involvement of full-time radiologists in the imaging workflow. In a national-level claims database, we identified 14,819 non-elderly patients (mean age: 38.7±8.0 years) who visited clinics/hospitals for low back pain in 2013-2015. We classified the clinics/hospitals into four groups based on the level of full-time radiologist involvement and MRI ownership, and compared the frequency of acute-period lumbar MRI using hierarchical logistic regression analysis. Patients visiting facilities without a full-time radiologist (n=2105) were significantly (p<0.001) more likely to undergo acute-period MRI than those visiting facilities with ≥1 radiologist partially managing imaging workflow (level-1, n=491) or ≥1 radiologist intensively involved in imaging workflow (level-2, n=1190) (15.7% vs. 6.9% and 7.3%; adjusted odds ratio of no-radiologist versus level-2: 2.93, p=0.018). No difference was observed between level-1 and level-2 involvement. Facilities with no full-time radiologist were more likely to perform acute-period MRI to assess for low back pain, while no difference was seen between facilities with varying levels of radiologist involvement in the imaging workflow. Radiologist involvement may contribute to optimal utilisation of medical imaging. (orig.)

  20. RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules

    Directory of Open Access Journals (Sweden)

    Michaeli Shulamit

    2007-10-01

    Full Text Available Abstract Background In recent years, RNA molecules that are not translated into proteins (ncRNAs have drawn a great deal of attention, as they were shown to be involved in many cellular functions. One of the most important computational problems regarding ncRNA is to predict the secondary structure of a molecule from its sequence. In particular, we attempted to predict the secondary structure for a set of unaligned ncRNA molecules that are taken from the same family, and thus presumably have a similar structure. Results We developed the RNAspa program, which comparatively predicts the secondary structure for a set of ncRNA molecules in linear time in the number of molecules. We observed that in a list of several hundred suboptimal minimal free energy (MFE predictions, as provided by the RNAsubopt program of the Vienna package, it is likely that at least one suggested structure would be similar to the true, correct one. The suboptimal solutions of each molecule are represented as a layer of vertices in a graph. The shortest path in this graph is the basis for structural predictions for the molecule. We also show that RNA secondary structures can be compared very rapidly by a simple string Edit-Distance algorithm with a minimal loss of accuracy. We show that this approach allows us to more deeply explore the suboptimal structure space. Conclusion The algorithm was tested on three datasets which include several ncRNA families taken from the Rfam database. These datasets allowed for comparison of the algorithm with other methods. In these tests, RNAspa performed better than four other programs.