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Sample records for shorter production schedule

  1. Homework schedule: an important factor associated with shorter sleep duration among Chinese school-aged children.

    Science.gov (United States)

    Li, Shenghui; Yang, Qian; Chen, Zhe; Jin, Xingming; Jiang, Fan; Shen, Xiaoming

    2014-09-03

    This study was designed to examine the hypothesis that homework schedule has adverse impacts on Chinese children's sleep-wake habits and sleep duration. A random sample of 19,299 children aged 5.08 to 11.99 years old participated in a large, cross-sectional survey. A parent-administered questionnaire was completed to quantify children's homework schedule and sleep behaviors. Generally, it was demonstrated that more homework schedule was significantly associated with later bedtime, later wake time, and shorter sleep duration. Among all sleep variables, bedtime and sleep duration during weekdays appeared to be most affected by homework schedule, especially homework schedule during weekdays.

  2. SHORTER MENSTRUAL CYCLES ASSOCIATED WITH CHLORINATION BY-PRODUCTS IN DRINKING WATER

    Science.gov (United States)

    Shorter Menstrual Cycles Associated with Chlorination by-Products in Drinking Water. Gayle Windham, Kirsten Waller, Meredith Anderson, Laura Fenster, Pauline Mendola, Shanna Swan. California Department of Health Services.In previous studies of tap water consumption we...

  3. Urdu translation and validation of shorter version of Positive Affect and Negative Affect Schedule (PANAS) on Pakistani bank employees.

    Science.gov (United States)

    Akhter, Noreen

    2017-10-01

    To translate, adapt and validate shorter version of positive affect and negative affect scale on Pakistani corporate employees. This cross-sectional study was conducted in the twin cities of Islamabad and Rawalpindi from October 2014 to December 2015. The study was completed into two independent parts. In part one, the scale was translated by forward translation. Then it was pilot-tested and administered on customer services employees from commercial banks and the telecommunication sector. Data of the pilot study was analysed by using exploratory factor analysis to extract the initial factor of positive affect and negative affect scale. Part two comprised the main study. Commercial bank employees were included in the sample using convenient sampling technique. Data of the main study was analysed using confirmatory factor analysis in order to establish construct validity of positive affect and negative affect scale. There were145 participants in the first part of the study and 495 in the second. Results of confirmatory factor analysis confirmed the two-factor structure of positive affect and negative affect scale suggesting that the scale has two distinct domains, i.e. positive affect and negative affect. The shorter version of positive affect and negative affect scale was found to be a valid and reliable measure.

  4. Nation-Scale Adoption of Shorter Breast Radiation Therapy Schedules Can Increase Survival in Resource Constrained Economies: Results From a Markov Chain Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Khan, Atif J., E-mail: atif.j.khan@rutgers.edu [Department of Radiation Oncology, Robert Wood Johnson Medical School/Cancer Institute of New Jersey, New Brunswick, New Jersey (United States); Rafique, Raza [Suleman Dawood School of Business, Lahore University of Management Sciences, Lahore (Pakistan); Zafar, Waleed [Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore (Pakistan); Shah, Chirag [Department of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio (United States); Haffty, Bruce G. [Department of Radiation Oncology, Robert Wood Johnson Medical School/Cancer Institute of New Jersey, New Brunswick, New Jersey (United States); Vicini, Frank [Michigan HealthCare Professionals, Farmington Hills, Michigan (United States); Jamshed, Arif [Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore (Pakistan); Zhao, Yao [Rutgers University School of Business, Newark, New Jersey (United States)

    2017-02-01

    Purpose: Hypofractionated whole breast irradiation and accelerated partial breast irradiation (APBI) offer women options for shorter courses of breast radiation therapy. The impact of these shorter schedules on the breast cancer populations of emerging economies with limited radiation therapy resources is unknown. We hypothesized that adoption of these schedules would improve throughput in the system and, by allowing more women access to life-saving treatments, improve patient survival within the system. Methods and Materials: We designed a Markov chain model to simulate the different health states that a postlumpectomy or postmastectomy patient could enter over the course of a 20-year follow-up period. Transition rates between health states were adapted from published data on recurrence rates. We used primary data from a tertiary care hospital in Lahore, Pakistan, to populate the model with proportional use of mastectomy versus breast conservation and to estimate the proportion of patients suitable for APBI. Sensitivity analyses on the use of APBI and relative efficacy of APBI were conducted to study the impact on the population. Results: The shorter schedule resulted in more women alive and more women remaining without evidence of disease (NED) compared with the conventional schedule, with an absolute difference of about 4% and 7% at 15 years, respectively. Among women who had lumpectomies, the chance of remaining alive and with an intact breast was 62% in the hypofractionation model and 54% in the conventional fractionation model. Conclusions: Increasing throughput in the system can result in improved survival, improved chances of remaining without evidence of disease, and improved chances of remaining alive with a breast. These findings are significant and suggest that adoption of hypofractionation in emerging economies is not simply a question of efficiency and cost but one of access to care and patient survivorship.

  5. Nation-Scale Adoption of Shorter Breast Radiation Therapy Schedules Can Increase Survival in Resource Constrained Economies: Results From a Markov Chain Analysis

    International Nuclear Information System (INIS)

    Khan, Atif J.; Rafique, Raza; Zafar, Waleed; Shah, Chirag; Haffty, Bruce G.; Vicini, Frank; Jamshed, Arif; Zhao, Yao

    2017-01-01

    Purpose: Hypofractionated whole breast irradiation and accelerated partial breast irradiation (APBI) offer women options for shorter courses of breast radiation therapy. The impact of these shorter schedules on the breast cancer populations of emerging economies with limited radiation therapy resources is unknown. We hypothesized that adoption of these schedules would improve throughput in the system and, by allowing more women access to life-saving treatments, improve patient survival within the system. Methods and Materials: We designed a Markov chain model to simulate the different health states that a postlumpectomy or postmastectomy patient could enter over the course of a 20-year follow-up period. Transition rates between health states were adapted from published data on recurrence rates. We used primary data from a tertiary care hospital in Lahore, Pakistan, to populate the model with proportional use of mastectomy versus breast conservation and to estimate the proportion of patients suitable for APBI. Sensitivity analyses on the use of APBI and relative efficacy of APBI were conducted to study the impact on the population. Results: The shorter schedule resulted in more women alive and more women remaining without evidence of disease (NED) compared with the conventional schedule, with an absolute difference of about 4% and 7% at 15 years, respectively. Among women who had lumpectomies, the chance of remaining alive and with an intact breast was 62% in the hypofractionation model and 54% in the conventional fractionation model. Conclusions: Increasing throughput in the system can result in improved survival, improved chances of remaining without evidence of disease, and improved chances of remaining alive with a breast. These findings are significant and suggest that adoption of hypofractionation in emerging economies is not simply a question of efficiency and cost but one of access to care and patient survivorship.

  6. Scheduling in Engineering, Project, and Production Management

    OpenAIRE

    Chien-Ho Ko

    2015-01-01

    This issue presents five papers selected from the 2013 (4th) International Conference on Engineering, Project, and Production Management (EPPM2013) held in Bangkok, Thailand. Three of the papers deal with scheduling problems faced in project and production management, while the remaining two focus on engineering management issues.

  7. Declarative Modeling for Production Order Portfolio Scheduling

    Directory of Open Access Journals (Sweden)

    Banaszak Zbigniew

    2014-12-01

    Full Text Available A declarative framework enabling to determine conditions as well as to develop decision-making software supporting small- and medium-sized enterprises aimed at unique, multi-project-like and mass customized oriented production is discussed. A set of unique production orders grouped into portfolio orders is considered. Operations executed along different production orders share available resources following a mutual exclusion protocol. A unique product or production batch is completed while following a given activity’s network order. The problem concerns scheduling a newly inserted project portfolio subject to constraints imposed by a multi-project environment The answers sought are: Can a given project portfolio specified by its cost and completion time be completed within the assumed time period in a manufacturing system in hand? Which manufacturing system capability guarantees the completion of a given project portfolio ordered under assumed cost and time constraints? The considered problems regard finding a computationally effective approach aimed at simultaneous routing and allocation as well as batching and scheduling of a newly ordered project portfolio subject to constraints imposed by a multi-project environment. The main objective is to provide a declarative model enabling to state a constraint satisfaction problem aimed at multi-project-like and mass customized oriented production scheduling. Multiple illustrative examples are discussed.

  8. Production planning and scheduling in refinery industry

    International Nuclear Information System (INIS)

    Persson, Jan.

    1999-01-01

    In this thesis we consider production planning and scheduling in refinery industry, in particular we study the planning and scheduling at the Nynaes AB refinery and at the Scanraff AB refinery. The purpose is to contribute to the development and the use of optimization models to support efficient decision making. We identify various decision problems concerning the aggregated production planning, the shipment planning, the scheduling of operation modes, and the utilization of pipes and tanks; and we discuss the potential to successfully apply optimization models on these problems. We formulate a mixed integer linear programming model for the scheduling of operation modes at Nynaes. The model concerns decisions about which mode of operation to use at a particular point in time in order to minimize costs of changing modes and costs of keeping inventories, given demands for products. We derive several types of valid inequalities for this mathematical problem and show how these inequalities can improve the lower bound obtained from the linear programming relaxation of the problem. We also show how the valid inequalities can be used to improve the performance of a branch and bound solution approach. Further, a tabu search heuristic is developed for the scheduling problem. The solution methods are tested on data provided by the Nynaes refinery, and the performance of the methods are discussed. We present several extensions of the proposed model, and illustrate how the model can be used to support both operational and strategic decision making at the refinery. 66 refs, 6 figs, 32 tabs. Also published as: Dissertation from the International Graduate School of Management and Industrial Engineering, No 25, Licenciate Thesis

  9. Production planning and scheduling in refinery industry

    Energy Technology Data Exchange (ETDEWEB)

    Persson, Jan

    1999-07-01

    In this thesis we consider production planning and scheduling in refinery industry, in particular we study the planning and scheduling at the Nynaes AB refinery and at the Scanraff AB refinery. The purpose is to contribute to the development and the use of optimization models to support efficient decision making. We identify various decision problems concerning the aggregated production planning, the shipment planning, the scheduling of operation modes, and the utilization of pipes and tanks; and we discuss the potential to successfully apply optimization models on these problems. We formulate a mixed integer linear programming model for the scheduling of operation modes at Nynaes. The model concerns decisions about which mode of operation to use at a particular point in time in order to minimize costs of changing modes and costs of keeping inventories, given demands for products. We derive several types of valid inequalities for this mathematical problem and show how these inequalities can improve the lower bound obtained from the linear programming relaxation of the problem. We also show how the valid inequalities can be used to improve the performance of a branch and bound solution approach. Further, a tabu search heuristic is developed for the scheduling problem. The solution methods are tested on data provided by the Nynaes refinery, and the performance of the methods are discussed. We present several extensions of the proposed model, and illustrate how the model can be used to support both operational and strategic decision making at the refinery. 66 refs, 6 figs, 32 tabs. Also published as: Dissertation from the International Graduate School of Management and Industrial Engineering, No 25, Licenciate Thesis.

  10. Production planning and scheduling in refinery industry

    Energy Technology Data Exchange (ETDEWEB)

    Persson, Jan

    1999-06-01

    In this thesis we consider production planning and scheduling in refinery industry, in particular we study the planning and scheduling at the Nynaes AB refinery and at the Scanraff AB refinery. The purpose is to contribute to the development and the use of optimization models to support efficient decision making. We identify various decision problems concerning the aggregated production planning, the shipment planning, the scheduling of operation modes, and the utilization of pipes and tanks; and we discuss the potential to successfully apply optimization models on these problems. We formulate a mixed integer linear programming model for the scheduling of operation modes at Nynaes. The model concerns decisions about which mode of operation to use at a particular point in time in order to minimize costs of changing modes and costs of keeping inventories, given demands for products. We derive several types of valid inequalities for this mathematical problem and show how these inequalities can improve the lower bound obtained from the linear programming relaxation of the problem. We also show how the valid inequalities can be used to improve the performance of a branch and bound solution approach. Further, a tabu search heuristic is developed for the scheduling problem. The solution methods are tested on data provided by the Nynaes refinery, and the performance of the methods are discussed. We present several extensions of the proposed model, and illustrate how the model can be used to support both operational and strategic decision making at the refinery. 66 refs, 6 figs, 32 tabs. Also published as: Dissertation from the International Graduate School of Management and Industrial Engineering, No 25, Licenciate Thesis

  11. Integrating Preventive Maintenance Scheduling As Probability Machine Failure And Batch Production Scheduling

    Directory of Open Access Journals (Sweden)

    Zahedi Zahedi

    2016-06-01

    Full Text Available This paper discusses integrated model of batch production scheduling and machine maintenance scheduling. Batch production scheduling uses minimize total actual flow time criteria and machine maintenance scheduling uses the probability of machine failure based on Weibull distribution. The model assumed no nonconforming parts in a planning horizon. The model shows an increase in the number of the batch (length of production run up to a certain limit will minimize the total actual flow time. Meanwhile, an increase in the length of production run will implicate an increase in the number of PM. An example was given to show how the model and algorithm work.

  12. Production Planning and Planting Pattern Scheduling Information System for Horticulture

    Science.gov (United States)

    Vitadiar, Tanhella Zein; Farikhin; Surarso, Bayu

    2018-02-01

    This paper present the production of planning and planting pattern scheduling faced by horticulture farmer using two methods. Fuzzy time series method use to predict demand on based on sales amount, while linear programming is used to assist horticulture farmers in making production planning decisions and determining the schedule of cropping patterns in accordance with demand predictions of the fuzzy time series method, variable use in this paper is size of areas, production advantage, amount of seeds and age of the plants. This research result production planning and planting patterns scheduling information system with the output is recommendations planting schedule, harvest schedule and the number of seeds will be plant.

  13. National contingency plan product schedule data base

    International Nuclear Information System (INIS)

    Putukian, J.; Hiltabrand, R.R.

    1993-01-01

    During oil spills there are always proposals by the technical community and industry to use chemical agents to help in oil spill cleanups. Federal Clean Water Act regulations require that any chemical agents that the federal on-scene coordinator (FOSC) wants to use for oil cleanup be listed on the US Environmental Protection Agency (EPA) National Contingency Plan (NCP) Product Schedule. Chemical countermeasures are among the most controversial, complex, and time-critical issues facing decision-making officials choosing response methods to use on coastal oil spills. There are situations in which dispersants are likely to be one of the most appropriate counter-measure strategies. Dispersants are most effective when applied to fresh oil, and their effectiveness dramatically decreases as the oil weathers, which can begin in as little as 24 hours. To logistically implement dispersant use, a decision would need to be made within roughly the first 4 hours after the release. Most of the information that the FOSC needs to make the determination to use a specific chemical agent exists in manuals, EPA bulletins, and the published literature. This information is not in an easy-to-use format under field emergency conditions. Hence the need to collect and disseminate the information in an automated data base. The sources for the information in this data base are the following. Published results of tests performed by Environment Canada; EPA bulletins associated with the NCP Product Schedule; Published results of tests by the chemical industry. The data base resides on a Macintosh computer and contains information about 70 NCP products, including dispersants, surface collecting agents, and biological additives. It contains information on physical properties, toxicity, heavy metal content, safety precautions, use conditions, etc

  14. Simulation methods for nuclear production scheduling

    International Nuclear Information System (INIS)

    Miles, W.T.; Markel, L.C.

    1975-01-01

    Recent developments and applications of simulation methods for use in nuclear production scheduling and fuel management are reviewed. The unique characteristics of the nuclear fuel cycle as they relate to the overall optimization of a mixed nuclear-fossil system in both the short-and mid-range time frame are described. Emphasis is placed on the various formulations and approaches to the mid-range planning problem, whose objective is the determination of an optimal (least cost) system operation strategy over a multi-year planning horizon. The decomposition of the mid-range problem into power system simulation, reactor core simulation and nuclear fuel management optimization, and system integration models is discussed. Present utility practices, requirements, and research trends are described. 37 references

  15. Conception of Self-Construction Production Scheduling System

    Science.gov (United States)

    Xue, Hai; Zhang, Xuerui; Shimizu, Yasuhiro; Fujimura, Shigeru

    With the high speed innovation of information technology, many production scheduling systems have been developed. However, a lot of customization according to individual production environment is required, and then a large investment for development and maintenance is indispensable. Therefore now the direction to construct scheduling systems should be changed. The final objective of this research aims at developing a system which is built by it extracting the scheduling technique automatically through the daily production scheduling work, so that an investment will be reduced. This extraction mechanism should be applied for various production processes for the interoperability. Using the master information extracted by the system, production scheduling operators can be supported to accelerate the production scheduling work easily and accurately without any restriction of scheduling operations. By installing this extraction mechanism, it is easy to introduce scheduling system without a lot of expense for customization. In this paper, at first a model for expressing a scheduling problem is proposed. Then the guideline to extract the scheduling information and use the extracted information is shown and some applied functions are also proposed based on it.

  16. A Method of Flow-Shop Re-Scheduling Dealing with Variation of Productive Capacity

    Directory of Open Access Journals (Sweden)

    Kenzo KURIHARA

    2005-02-01

    Full Text Available We can make optimum scheduling results using various methods that are proposed by many researchers. However, it is very difficult to process the works on time without delaying the schedule. There are two major causes that disturb the planned optimum schedules; they are (1the variation of productive capacity, and (2the variation of products' quantities themselves. In this paper, we deal with the former variation, or productive capacities, at flow-shop works. When production machines in a shop go out of order at flow-shops, we cannot continue to operate the productions and we have to stop the production line. To the contrary, we can continue to operate the shops even if some workers absent themselves. Of course, in this case, the production capacities become lower, because workers need to move from a machine to another to overcome the shortage of workers and some shops cannot be operated because of the worker shortage. We developed a new re-scheduling method based on Branch-and Bound method. We proposed an equation for calculating the lower bound for our Branch-and Bound method in a practical time. Some evaluation experiments are done using practical data of real flow-shop works. We compared our results with those of another simple scheduling method, and we confirmed the total production time of our result is shorter than that of another method by 4%.

  17. Modeling of Agile Intelligent Manufacturing-oriented Production Scheduling System

    Institute of Scientific and Technical Information of China (English)

    Zhong-Qi Sheng; Chang-Ping Tang; Ci-Xing Lv

    2010-01-01

    Agile intelligent manufacturing is one of the new manufacturing paradigms that adapt to the fierce globalizing market competition and meet the survival needs of the enterprises, in which the management and control of the production system have surpassed the scope of individual enterprise and embodied some new features including complexity, dynamicity, distributivity, and compatibility. The agile intelligent manufacturing paradigm calls for a production scheduling system that can support the cooperation among various production sectors, the distribution of various resources to achieve rational organization, scheduling and management of production activities. This paper uses multi-agents technology to build an agile intelligent manufacturing-oriented production scheduling system. Using the hybrid modeling method, the resources and functions of production system are encapsulated, and the agent-based production system model is established. A production scheduling-oriented multi-agents architecture is constructed and a multi-agents reference model is given in this paper.

  18. Freezing the Master Production Schedule Under Rolling Planning Horizons

    OpenAIRE

    V. Sridharan; William L. Berry; V. Udayabhanu

    1987-01-01

    The stability of the Master Production Schedule (MPS) is a critical issue in managing production operations with a Material Requirements Planning System. One method of achieving stability is to freeze some portion or all of the MPS. While freezing the MPS can limit the number of schedule changes, it can also produce an increase in production and inventory costs. This paper examines three decision variables in freezing the MPS: the freezing method, the freeze interval length, and the planning ...

  19. Nonlinear Price Schedules and Tied Products.

    OpenAIRE

    Ormiston, Michael B; Phillips, Owen R

    1988-01-01

    Illegal tying often occurs when a monopolist jointly sells a product with a complementary requirement, also sold competitively. Along with selling the complement at its competi tive price, this paper shows that profit can increase when a monopoli st lets consumers bundle any amount of the requirement with the basic product at a fixed price. Examples illustrate demand conditions that enhance the profitability of this nonlinear price strategy and show that profits can approximate those earned f...

  20. Sharing data for production scheduling using the ISA-95 standard

    Directory of Open Access Journals (Sweden)

    Iiro eHarjunkoski

    2014-10-01

    Full Text Available In the development and deployment of production scheduling solutions one major challenge is to establish efficient information sharing with industrial production management systems. Information comprising production orders to be scheduled, processing plant structure, product recipes, available equipment and other resources are necessary for producing a realistic short-term production plan. Currently, a widely-accepted standard for information sharing is missing. This often leads to the implementation of costly custom-tailored interfaces, or in the worst case the scheduling solution will be abandoned. Additionally, it becomes difficult to easily compare different methods on various problem instances, which complicates the re-use of existing scheduling solutions. In order to overcome these hurdles, a platform-independent and holistic approach is needed. Nevertheless, it is difficult for any new solution to gain wide acceptance within industry as new standards are often refused by companies already using a different established interface. From an acceptance point of view, the ISA-95 standard could act as a neutral data-exchange platform. In this paper, we assess if this already widespread standard is simple, yet powerful enough to act as the desired holistic data-exchange for scheduling solutions.

  1. Sharing Data for Production Scheduling Using the ISA-95 Standard

    Energy Technology Data Exchange (ETDEWEB)

    Harjunkoski, Iiro, E-mail: iiro.harjunkoski@de.abb.com; Bauer, Reinhard [ABB Corporate Research, Industrial Software and Applications, Ladenburg (Germany)

    2014-10-21

    In the development and deployment of production scheduling solutions, one major challenge is to establish efficient information sharing with industrial production management systems. Information comprising production orders to be scheduled, processing plant structure, product recipes, available equipment, and other resources are necessary for producing a realistic short-term production plan. Currently, a widely accepted standard for information sharing is missing. This often leads to the implementation of costly custom-tailored interfaces, or in the worst case the scheduling solution will be abandoned. Additionally, it becomes difficult to easily compare different methods on various problem instances, which complicates the re-use of existing scheduling solutions. In order to overcome these hurdles, a platform-independent and holistic approach is needed. Nevertheless, it is difficult for any new solution to gain wide acceptance within industry as new standards are often refused by companies already using a different established interface. From an acceptance point of view, the ISA-95 standard could act as a neutral data-exchange platform. In this paper, we assess if this already widespread standard is simple, yet powerful enough to act as the desired holistic data exchange for scheduling solutions.

  2. Sharing Data for Production Scheduling Using the ISA-95 Standard

    International Nuclear Information System (INIS)

    Harjunkoski, Iiro; Bauer, Reinhard

    2014-01-01

    In the development and deployment of production scheduling solutions, one major challenge is to establish efficient information sharing with industrial production management systems. Information comprising production orders to be scheduled, processing plant structure, product recipes, available equipment, and other resources are necessary for producing a realistic short-term production plan. Currently, a widely accepted standard for information sharing is missing. This often leads to the implementation of costly custom-tailored interfaces, or in the worst case the scheduling solution will be abandoned. Additionally, it becomes difficult to easily compare different methods on various problem instances, which complicates the re-use of existing scheduling solutions. In order to overcome these hurdles, a platform-independent and holistic approach is needed. Nevertheless, it is difficult for any new solution to gain wide acceptance within industry as new standards are often refused by companies already using a different established interface. From an acceptance point of view, the ISA-95 standard could act as a neutral data-exchange platform. In this paper, we assess if this already widespread standard is simple, yet powerful enough to act as the desired holistic data exchange for scheduling solutions.

  3. Simulation of less master production schedule nervousness model

    OpenAIRE

    Herrera , Carlos; Thomas , André

    2009-01-01

    International audience; In production decision making systems, Master Production Schedule (MPS) states the requirements for individual end items by date and quantity. The solution sensitivity to demand forecast changes, unforeseen supplier and production problem occurrences, is known as nervousness. This feature cause undesirable effects at tactical and operational levels. Some of these effects are production and inventory cost increases and, also, negative impacts on overall and labor produc...

  4. The role of the production scheduling system in rescheduling

    Science.gov (United States)

    Kalinowski, K.; Grabowik, C.; Kempa, W.; Paprocka, I.

    2015-11-01

    The paper presents the rescheduling problem in the context of cooperation between production scheduling system (PSS) and other units in an integrated manufacturing environment - decision makers and software systems. The main aim is to discuss the PSS functionality for maximizing automation of the rescheduling process, reducing the response time and improving the quality of generated solutions. PSSs operate in the meeting of tactical and operational level of planning and control, and play an important role in the production preparation and control. On the basis of information about orders, technology and production system state (e.g. resources availability) they prepare and/or update a detailed plan of production flow - a schedule. All necessary data for scheduling and rescheduling are usually collected in other systems both from organizational and technical production preparation, e.g. ERP, PLM, MES, CAPP or others, as well as they are entered directly by the decision- makers/operators. Data acquired in this way are often incomplete and inconsistent. Therefore the existing rescheduling software works according to interactive method - rather support but does not replace the human decision maker in tasks planning. When rescheduling, due to the limited amount of time to make a decision this interaction is particularly important. An additional problem arises in data acquisition, in the process of data exchanging between systems or in the identification of new data sources and their processing. Different approaches to rescheduling were characterized, including those solutions, where all these operations are carried out by an autonomous system and those in which scheduling is performed only upon request from the outside, for the newly created scheduling data representing the current state of the production system.

  5. Joint optimization of production scheduling and machine group preventive maintenance

    International Nuclear Information System (INIS)

    Xiao, Lei; Song, Sanling; Chen, Xiaohui; Coit, David W.

    2016-01-01

    Joint optimization models were developed combining group preventive maintenance of a series system and production scheduling. In this paper, we propose a joint optimization model to minimize the total cost including production cost, preventive maintenance cost, minimal repair cost for unexpected failures and tardiness cost. The total cost depends on both the production process and the machine maintenance plan associated with reliability. For the problems addressed in this research, any machine unavailability leads to system downtime. Therefore, it is important to optimize the preventive maintenance of machines because their performance impacts the collective production processing associated with all machines. Too lengthy preventive maintenance intervals may be associated with low scheduled machine maintenance cost, but may incur expensive costs for unplanned failure due to low machine reliability. Alternatively, too frequent preventive maintenance activities may achieve the desired high reliability machines, but unacceptably high scheduled maintenance cost. Additionally, product scheduling plans affect tardiness and maintenance cost. Two results are obtained when solving the problem; the optimal group preventive maintenance interval for machines, and the assignment of each job, including the corresponding start time and completion time. To solve this non-deterministic polynomial-time problem, random keys genetic algorithms are used, and a numerical example is solved to illustrate the proposed model. - Highlights: • Group preventive maintenance (PM) planning and production scheduling are jointed. • Maintenance interval and assignment of jobs are decided by minimizing total cost. • Relationships among system age, PM, job processing time are quantified. • Random keys genetic algorithms (GA) are used to solve the NP-hard problem. • Random keys GA and Particle Swarm Optimization (PSO) are compared.

  6. optimal scheduling of petroleum products distribution in nigeria

    African Journals Online (AJOL)

    MECHANICAL ENGINEERING

    The study reveals that any variation in supply, demand and ... and storage depots for easy shipment of the products from ... The system should be robust yet simple to support routine ..... (10)Klabjan, D. Topics in airline crew scheduling and ...

  7. A stochastic simulation approach for production scheduling and ...

    African Journals Online (AJOL)

    International Journal of Engineering, Science and Technology ... management decisions related to production scheduling and investment planning. ... and indicate the value of promoting an information culture in the entire work forces. ... to support decision making in a BPR (Business Processes Re-engineering) scenario.

  8. Formulation for less master production schedule instability under rolling horizon

    OpenAIRE

    Herrera , Carlos; Thomas , André

    2009-01-01

    International audience; In Manufacturing Planning and Control Systems, the Master Production Schedule (MPS) makes a link between tactical and operational levels, taking into account information provided by end items, demand forecast as well as Sales and Operations Planning (S&OP) suggestions. Therefore, MPS plays an important role to maintain an adequate customers service level and an efficient production system. In a rolling planning horizon, MPS is periodically computed over whole operation...

  9. Interface between the production plan and the master production schedule in assembly environments

    OpenAIRE

    Moya Navarro, Marcos; Sánchez Brenes, Magaly

    2012-01-01

    In a production environment there is a direct relationship between the market and the manufacturing process of goods.When production is immersed in an assembly environment, the process of production planning and scheduling becomes complex, and the enterprises have the risk of losing competitive advantages in terms of not meeting delivery dates and production high costs. Linear programming has become an appropriate tool for production planning and scheduling in complex manufacturing environmen...

  10. Refinery production planning and scheduling: the refining core business

    Directory of Open Access Journals (Sweden)

    M. Joly

    2012-06-01

    Full Text Available Intelligent production planning and scheduling are of paramount importance to ensure refinery profitability, logistic reliability and safety at the local and corporate levels. In Brazil, such activities play a particularly critical role, since the Brazilian downstream model is moving towards a demand-driven model rather than a supply-driven one. Moreover, new and specialized non-linear constraints are continuously being incorporated into these large-scale problems: increases in oil prices implying the need for processing poor quality crudes, increasing demand and new demand patterns for petroleum products, new stringent environmental regulations related to clean fuels and start-up of new production technologies embedded into more complex refining schemes. This paper aims at clarifying the central role of refinery planning and scheduling activities in the Petrobras refining business. Major past and present results are outlined and corporate long-term strategies to deal with present and future challenges are presented.

  11. A Formal Product-Line Engineering Approach for Schedulers

    NARCIS (Netherlands)

    Orhan, Güner; Aksit, Mehmet; Rensink, Arend; Jololian, Leon; Robbins, David E.; Fernandes, Steven L.

    2017-01-01

    Scheduling techniques have been applied to a large category of software systems, such as, processor scheduling in operating systems, car scheduling in elevator systems, facility scheduling at airports, antenna scheduling in radar systems, scheduling of events, control signals and data in

  12. Integrated Production-Distribution Scheduling Problem with Multiple Independent Manufacturers

    Directory of Open Access Journals (Sweden)

    Jianhong Hao

    2015-01-01

    Full Text Available We consider the nonstandard parts supply chain with a public service platform for machinery integration in China. The platform assigns orders placed by a machinery enterprise to multiple independent manufacturers who produce nonstandard parts and makes production schedule and batch delivery schedule for each manufacturer in a coordinate manner. Each manufacturer has only one plant with parallel machines and is located at a location far away from other manufacturers. Orders are first processed at the plants and then directly shipped from the plants to the enterprise in order to be finished before a given deadline. We study the above integrated production-distribution scheduling problem with multiple manufacturers to maximize a weight sum of the profit of each manufacturer under the constraints that all orders are finished before the deadline and the profit of each manufacturer is not negative. According to the optimal condition analysis, we formulate the problem as a mixed integer programming model and use CPLEX to solve it.

  13. Driving for shorter outages

    International Nuclear Information System (INIS)

    Tritch, S.

    1996-01-01

    Nuclear plant outages are necessary to complete activities that cannot be completed during the operating cycle, such as steam generator inspection and testing, refueling, installing modifications, and performing maintenance tests. The time devoted to performing outages is normally the largest contributor to plant unavailability. Similarly, outage costs are a sizable portion of the total plant budget. The scope and quality of work done during outages directly affects operating reliability and the number of unplanned outages. Improved management and planning of outages enhances the margin of safety during the outage and results in increased plant reliability. The detailed planning and in-depth preparation that has become a necessity for driving shorter outage durations has also produced safer outages and improved post-outage reliability. Short outages require both plant and vendor management to focus on all aspects of the outage. Short outage durations, such as 26 days at South Texas or 29 days at North Anna, require power plant inter-department and intra-department teamwork and communication and vendor participation. In this paper shorter and safer outage at the 3-loop plants in the United States are explained. (J.P.N.)

  14. 12-hour-shift plant schedule improves operator productivity

    International Nuclear Information System (INIS)

    Gould, S.

    1989-01-01

    Twelve-hour scheduling has been a mainstay of the petrochemical industry, is common in the papermill industry, and is relatively new to the nuclear utility industry. A review of industry experiences, research, and a federal Nuclear Regulatory Commission (NRC) study of the 12-hour shift (NUREG/CR-4248) demonstrate that the advantages outweigh the disadvantages. The primary advantages are greater job satisfaction, fewer errors, and the better communications inherent in two shift turnovers versus three. Several companies that implemented the 12-hour shift found an increase in employee morale, no adverse effect on worker health, and no decline in safety. They experienced greater productivity, fewer operator errors, and better communication

  15. A new mathematical programming model for long-term production scheduling considering geological uncertainty

    OpenAIRE

    Gholamnejad, J.; Moosavi, E.

    2012-01-01

    Determination of the optimum production schedules over the life of a mine is a critical mechanism in open pit mine planning procedures. Long-term production scheduling is used to maximize the net present value of the project under technical, financial, and environmental constraints. Mathematical programming models are well suited for optimizing long-term production schedules of open pit mines. There are two approaches to solving long-term production problems: deterministic- and uncertainty- b...

  16. 78 FR 55099 - Established Aggregate Production Quotas for Schedule I and II Controlled Substances and...

    Science.gov (United States)

    2013-09-09

    ... aggregate production quotas, an additional 25% of the estimated medical, scientific, and research needs as... Production Quotas for Schedule I and II Controlled Substances and Established Assessment of Annual Needs for... initial 2014 aggregate production quotas for controlled substances in Schedules I and II of the Controlled...

  17. Quality Improvement, Inventory Management, Lead Time Reduction and Production Scheduling in High-Mix Manufacturing Environments

    Science.gov (United States)

    2017-01-13

    Quality Improvement , Inventory Management, Lead Time Reduction and Production Scheduling in High-mix Manufacturing Environments by Sean Daigle B.S...Mechanical Engineering Chairman, Department Committee on Graduate Theses 2 Quality Improvement , Inventory Management, Lead Time Reduction and... Production Scheduling in High-mix Manufacturing Environments by Sean Daigle Submitted to the Department of Mechanical Engineering on January 13, 2017, in

  18. Research on the ITOC based scheduling system for ship piping production

    Science.gov (United States)

    Li, Rui; Liu, Yu-Jun; Hamada, Kunihiro

    2010-12-01

    Manufacturing of ship piping systems is one of the major production activities in shipbuilding. The schedule of pipe production has an important impact on the master schedule of shipbuilding. In this research, the ITOC concept was introduced to solve the scheduling problems of a piping factory, and an intelligent scheduling system was developed. The system, in which a product model, an operation model, a factory model, and a knowledge database of piping production were integrated, automated the planning process and production scheduling. Details of the above points were discussed. Moreover, an application of the system in a piping factory, which achieved a higher level of performance as measured by tardiness, lead time, and inventory, was demonstrated.

  19. 15 CFR 714.3 - Advance declaration requirements for additionally planned production of Schedule 3 chemicals.

    Science.gov (United States)

    2010-01-01

    ... COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 3 CHEMICALS § 714.3 Advance... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Advance declaration requirements for additionally planned production of Schedule 3 chemicals. 714.3 Section 714.3 Commerce and Foreign Trade...

  20. 78 FR 37237 - Proposed Adjustments to the Aggregate Production Quotas for Schedule I and II Controlled...

    Science.gov (United States)

    2013-06-20

    ... class of controlled substance listed in schedules I and II and for ephedrine, pseudoephedrine, and... disposal by the registrants holding individual manufacturing quotas for the class; (2) whether any... the Aggregate Production Quotas for Schedule I and II Controlled Substances and Assessment of Annual...

  1. Effective Schedule and Cost Management as a Product Development Lead

    Science.gov (United States)

    Simmons, Cynthia

    2015-01-01

    The presentation will be given at the 26th Annual Thermal Fluids Analysis Workshop (TFAWS 2015) hosted by the Goddard SpaceFlight Center (GSFC) Thermal Engineering Branch (Code 545). This course provides best practices, helpful tools and lessons learned for staying on plan and day-to-day management of Subsystem flight development after getting Project approval for your Subsystem schedule and budget baseline.

  2. Uncertainty management by relaxation of conflicting constraints in production process scheduling

    Science.gov (United States)

    Dorn, Juergen; Slany, Wolfgang; Stary, Christian

    1992-01-01

    Mathematical-analytical methods as used in Operations Research approaches are often insufficient for scheduling problems. This is due to three reasons: the combinatorial complexity of the search space, conflicting objectives for production optimization, and the uncertainty in the production process. Knowledge-based techniques, especially approximate reasoning and constraint relaxation, are promising ways to overcome these problems. A case study from an industrial CIM environment, namely high-grade steel production, is presented to demonstrate how knowledge-based scheduling with the desired capabilities could work. By using fuzzy set theory, the applied knowledge representation technique covers the uncertainty inherent in the problem domain. Based on this knowledge representation, a classification of jobs according to their importance is defined which is then used for the straightforward generation of a schedule. A control strategy which comprises organizational, spatial, temporal, and chemical constraints is introduced. The strategy supports the dynamic relaxation of conflicting constraints in order to improve tentative schedules.

  3. A Recovery Model for Production Scheduling: Combination of Disruption Management and Internet of Things

    Directory of Open Access Journals (Sweden)

    Yang Jiang

    2016-01-01

    Full Text Available It is difficult to generate the new schedule effectively for minimizing the negative impact when an unanticipated disruption occurs after a subset of tasks has been finished in production scheduling. In such cases, continuing with the original schedule may not be optimal or feasible. Based on disruption management and Internet of things (IoT, this study designs a real-time status analyzer to identify the disruption and propose a recovery model to deal with the disruption. The computational result proves that our algorithm is competitive with the existing heuristics. Furthermore, due to the tradeoff between all participators (mainly including customers, managers of production enterprise, and workers involved in production scheduling, our model is more effective than the total rescheduling and right-shift rescheduling.

  4. 10 CFR 170.21 - Schedule of fees for production and utilization facilities, review of standard referenced design...

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Schedule of fees for production and utilization facilities, review of standard referenced design approvals, special projects, inspections and import and export... AMENDED Schedule of Fees § 170.21 Schedule of fees for production and utilization facilities, review of...

  5. A shorter fractionation schedule for postlumpectomy breast cancer patients

    International Nuclear Information System (INIS)

    Shelley, Wendy; Brundage, Michael; Hayter, Charles; Paszat, Lawrence; Zhou, Sam; Mackillop, William

    2000-01-01

    Purpose: The purpose of this retrospective review was to determine the effectiveness of 40 Gy in 16 daily fractions in preventing local recurrence in postlumpectomy invasive breast cancer patients whose margins of resection were clear of tumor by at least 2 mm. Methods: Between September 1989 and December 1993, 294 breasts were treated with this regimen. The entire breast was treated, using a tangential parallel pair, with wedges as necessary, to a dose of 40 Gy in 16 daily fractions. No additional boost was given. The median duration of follow-up of surviving patients is 5.5 years. Recently, the patients' assessment of the cosmetic outcome of their treatment was obtained, using a mailed questionnaire. Results: The 5-year actuarial breast-relapse rate was 3.5%, with an overall 5-year survival and disease-specific survival of 87.8% and 92.1%, respectively. In response to the cosmesis questionnaire, 77% of patients stated they were either extremely or very satisfied with the overall appearance of the breast, 19.5% moderately satisfied, and 3.5% either slightly or not at all satisfied. The corresponding responses for overall level of comfort of the breast were 79%, 16.5%, and 4.5% respectively. Conclusion: This regimen is very effective at preventing recurrent breast cancer in this group of patients, and it provides a high level of patient satisfaction with cosmetic outcome. Its short duration offers the added advantage of a more efficient use of resources and greater patient convenience

  6. Scheduling Production Orders, Taking into Account Delays and Waste

    Directory of Open Access Journals (Sweden)

    Dylewski Robert

    2014-09-01

    Full Text Available The article addresses the problem of determining the sequence of entering orders for production in a flexible manufacturing system implementing technological operations of cutting sheet metal. Adopting a specific ranking of production orders gives rise to the vector of delays and waste in the form of incompletely used sheets. A new method was postulated for determining the optimal sequence of orders in terms of two criteria: the total cost of delays and the amount of production waste. The examples illustrate the advantages of the proposed method compared with the popular heuristic principles.

  7. Operational Excellence through Schedule Optimization and Production Simulation of Application Specific Integrated Circuits.

    Energy Technology Data Exchange (ETDEWEB)

    Flory, John Andrew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Padilla, Denise D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gauthier, John H. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Zwerneman, April Marie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Miller, Steven P [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-05-01

    Upcoming weapon programs require an aggressive increase in Application Specific Integrated Circuit (ASIC) production at Sandia National Laboratories (SNL). SNL has developed unique modeling and optimization tools that have been instrumental in improving ASIC production productivity and efficiency, identifying optimal operational and tactical execution plans under resource constraints, and providing confidence in successful mission execution. With ten products and unprecedented levels of demand, a single set of shared resources, highly variable processes, and the need for external supplier task synchronization, scheduling is an integral part of successful manufacturing. The scheduler uses an iterative multi-objective genetic algorithm and a multi-dimensional performance evaluator. Schedule feasibility is assessed using a discrete event simulation (DES) that incorporates operational uncertainty, variability, and resource availability. The tools provide rapid scenario assessments and responses to variances in the operational environment, and have been used to inform major equipment investments and workforce planning decisions in multiple SNL facilities.

  8. Innovative Production Scheduling with Customer Satisfaction Based Measurement for the Sustainability of Manufacturing Firms

    Directory of Open Access Journals (Sweden)

    Sang-Oh Shim

    2017-12-01

    Full Text Available Scheduling problems for the sustainability of manufacturing firms in the era of the fourth industrial revolution is addressed in this research. In terms of open innovation, innovative production scheduling can be defined as scheduling using big data, cyber-physical systems, internet of things, cloud computing, mobile network, and so on. In this environment, one of the most important things is to develop an innovative scheduling algorithm for the sustainability of manufacturing firms. In this research, a flexible flowshop scheduling problem is considered with the properties of sequence-dependent setup and different process plans for jobs. In a flexible flowshop, there are serial workstations with multiple pieces of equipment that are able to process multiple lots simultaneously. Since the scheduling in this workshop is known to be extremely difficult, it is important to devise an efficient and effective scheduling algorithm. In this research, a heuristic algorithm is proposed based on a few dispatching rules and economic lot size model with the objective of minimizing total tardiness of orders. For the purposes of performance evaluation, a simulation study is conducted on randomly generated problem instances. The results imply that our proposed method outperforms the existing ones, and greatly enhances the sustainability of manufacturing firms.

  9. An MILP approach to shelf life integrated planning and scheduling in scalded sausage production

    DEFF Research Database (Denmark)

    Günther, H.O.; van Beek, P.; Grunow, Martin

    2006-01-01

    in which shelf life aspects are integrated into operational production planning and scheduling functions. Specifically we make use of so-called Mixed Integer Linear Programming (MILP) models. Our research is based on an industrial case study of yogurt production. Relying on the principle of block planning...

  10. Production and Resource Scheduling in Mass Customization with Dependent Setup Consideration

    DEFF Research Database (Denmark)

    Nielsen, Izabela Ewa; Bocewicz, G.; Do, Ngoc Anh Dung

    2014-01-01

    will contribute to the success of mass customization. This paper addresses the problem of production and resource scheduling for a production system with dependent setup and internal transportation such as AGVs in a mass customization environment. A constraint-programming-based methodology is developed to satisfy...

  11. Decomposition principles applied to the dynamic production and work-force scheduling problem

    NARCIS (Netherlands)

    Aardal, K.I.; Ari, A.

    1987-01-01

    One of the most important problems in the production and inventory planning field, is the scheduling of production and work force in a dynamic environment. Although this problem can be formulated as a linear program, it is often quite difficult to solve directly, due to its large scale. Instead, it

  12. Managing unforeseen events in production scheduling and control

    DEFF Research Database (Denmark)

    Arica, E.; Falster, Peter; Hvolby, H. H.

    2016-01-01

    initial plans unfeasible or obsolete during production execution. How to effectively handle the unscheduled events and take corrective actions still remains a central question to academics and practitioners. In this paper, we explore this issue through a review of the relevant literature and an in......The production planning and control process is performed within complex and dynamic organizations made up of customer expectations, equipment, materials, people, information, and technologies. Changes in both internal and external factors can create a variety of unforeseen events, which make...

  13. A reactive decision-making approach to reduce instability in a Master Production Schedule

    OpenAIRE

    Herrera , Carlos; Belmokhtar Berraf , Sana; Thomas , André; Parada , Victor

    2016-01-01

    International audience; One of the primary factors that impact the master production scheduling performance is demand fluctuation, which leads to frequently updated decisions, thereby causing instability. Consequently, global cost deteriorates, and productivity decreases. A reactive approach based on parametric mixed-integer programming is proposed that aims to provide a set of plans such that a compromise between production cost and production stability is ensured. Several stability measures...

  14. Research on Energy-Saving Production Scheduling Based on a Clustering Algorithm for a Forging Enterprise

    Directory of Open Access Journals (Sweden)

    Yifei Tong

    2016-02-01

    Full Text Available Energy efficiency is a buzzword of the 21st century. With the ever growing need for energy efficient and low-carbon production, it is a big challenge for high energy-consumption enterprises to reduce their energy consumption. To this aim, a forging enterprise, DVR (the abbreviation of a forging enterprise, is researched. Firstly, an investigation into the production processes of DVR is given as well as an analysis of forging production. Then, the energy-saving forging scheduling is decomposed into two sub-problems. One is for cutting and machining scheduling, which is similar to traditional machining scheduling. The other one is for forging and heat treatment scheduling. Thirdly, former forging production scheduling is presented and solved based on an improved genetic algorithm. Fourthly, the latter is discussed in detail, followed by proposed dynamic clustering and stacking combination optimization. The proposed stacking optimization requires making the gross weight of forgings as close to the maximum batch capacity as possible. The above research can help reduce the heating times, and increase furnace utilization with high energy efficiency and low carbon emissions.

  15. Planning Risk-Based SQC Schedules for Bracketed Operation of Continuous Production Analyzers.

    Science.gov (United States)

    Westgard, James O; Bayat, Hassan; Westgard, Sten A

    2018-02-01

    To minimize patient risk, "bracketed" statistical quality control (SQC) is recommended in the new CLSI guidelines for SQC (C24-Ed4). Bracketed SQC requires that a QC event both precedes and follows (brackets) a group of patient samples. In optimizing a QC schedule, the frequency of QC or run size becomes an important planning consideration to maintain quality and also facilitate responsive reporting of results from continuous operation of high production analytic systems. Different plans for optimizing a bracketed SQC schedule were investigated on the basis of Parvin's model for patient risk and CLSI C24-Ed4's recommendations for establishing QC schedules. A Sigma-metric run size nomogram was used to evaluate different QC schedules for processes of different sigma performance. For high Sigma performance, an effective SQC approach is to employ a multistage QC procedure utilizing a "startup" design at the beginning of production and a "monitor" design periodically throughout production. Example QC schedules are illustrated for applications with measurement procedures having 6-σ, 5-σ, and 4-σ performance. Continuous production analyzers that demonstrate high σ performance can be effectively controlled with multistage SQC designs that employ a startup QC event followed by periodic monitoring or bracketing QC events. Such designs can be optimized to minimize the risk of harm to patients. © 2017 American Association for Clinical Chemistry.

  16. Shorter Harvest Cycles Counteract Increasing Annual Productivity in Industrial Plantation Forests: Trends from Three Decades of Remote Sensing in Southeastern Brazil

    Science.gov (United States)

    McMahon, D.; Jackson, R. B.

    2017-12-01

    Plantation forestry can produce woody biomass many times faster than native vegetation, particularly in the tropical regions where plantations have expanded rapidly in the past three decades. However, activists and practitioners have raised concerns over the sustainability of intensive plantations, suggesting that changes to soil properties may inhibit vegetation growth after multiple harvest cycles. We use a 32-year time series of remotely sensed vegetation indices derived from Landsat data, coupled with recent geospatial and wood volume data from plantation companies, to identify trends in management and vegetation productivity in thousands of individual eucalyptus plantation stands. We find that peak vegetation index values at canopy closure, which are correlated with annual wood volume increment, increase over successive harvest cycles, while the length of each cycle decreases. These opposing trends suggest that the number of harvests required to produce a given wood volume peaks around the second harvest cycle and then declines, likely due to refinement of management practices. Across the region, vegetation index data do not support the hypothesized decrease in productivity over multiple harvest cycles. Additional field data and ongoing soil analyses will complement the remote sensing approach to quantifying plantations' long-term effects on the land they occupy.

  17. Integration of scheduling and discrete event simulation systems to improve production flow planning

    Science.gov (United States)

    Krenczyk, D.; Paprocka, I.; Kempa, W. M.; Grabowik, C.; Kalinowski, K.

    2016-08-01

    The increased availability of data and computer-aided technologies such as MRPI/II, ERP and MES system, allowing producers to be more adaptive to market dynamics and to improve production scheduling. Integration of production scheduling and computer modelling, simulation and visualization systems can be useful in the analysis of production system constraints related to the efficiency of manufacturing systems. A integration methodology based on semi-automatic model generation method for eliminating problems associated with complexity of the model and labour-intensive and time-consuming process of simulation model creation is proposed. Data mapping and data transformation techniques for the proposed method have been applied. This approach has been illustrated through examples of practical implementation of the proposed method using KbRS scheduling system and Enterprise Dynamics simulation system.

  18. Retail sales of scheduled listed chemical products; self-certification of regulated sellers of scheduled listed chemical products. Interim final rule with request for comment.

    Science.gov (United States)

    2006-09-26

    In March 2006, the President signed the Combat Methamphetamine Epidemic Act of 2005, which establishes new requirements for retail sales of over-the-counter (nonprescription) products containing the List I chemicals ephedrine, pseudoephedrine, and phenylpropanolamine. The three chemicals can be used to manufacture methamphetamine illegally. DEA is promulgating this rule to incorporate the statutory provisions and make its regulations consistent with the new requirements. This action establishes daily and 30-day limits on the sales of scheduled listed chemical products to individuals and requires recordkeeping on most sales.

  19. Scheduling a Single Mobile Robot Incorporated into Production Environment

    DEFF Research Database (Denmark)

    Dang, Vinh Quang; Nielsen, Izabela Ewa; Steger-Jensen, Kenn

    2013-01-01

    to the challenges of issues such as energy conservation and pollution preventions. Facing the central tension between manufacturing and environmental drivers is difficult, but critical to develop new technologies, particularly mobile robots, that can be incorporated into production to achieve holistic solutions....... This chapter deals with the problem of finding optimal operating sequence in a manufacturing cell of a mobile robot with manipulation arm that feeds materials to feeders. The “Bartender Concept” is discussed to show the cooperation between the mobile robot and industrial environment. The performance criterion...

  20. Cost Minimization for Joint Energy Management and Production Scheduling Using Particle Swarm Optimization

    Science.gov (United States)

    Shah, Rahul H.

    Production costs account for the largest share of the overall cost of manufacturing facilities. With the U.S. industrial sector becoming more and more competitive, manufacturers are looking for more cost and resource efficient working practices. Operations management and production planning have shown their capability to dramatically reduce manufacturing costs and increase system robustness. When implementing operations related decision making and planning, two fields that have shown to be most effective are maintenance and energy. Unfortunately, the current research that integrates both is limited. Additionally, these studies fail to consider parameter domains and optimization on joint energy and maintenance driven production planning. Accordingly, production planning methodology that considers maintenance and energy is investigated. Two models are presented to achieve well-rounded operating strategy. The first is a joint energy and maintenance production scheduling model. The second is a cost per part model considering maintenance, energy, and production. The proposed methodology will involve a Time-of-Use electricity demand response program, buffer and holding capacity, station reliability, production rate, station rated power, and more. In practice, the scheduling problem can be used to determine a joint energy, maintenance, and production schedule. Meanwhile, the cost per part model can be used to: (1) test the sensitivity of the obtained optimal production schedule and its corresponding savings by varying key production system parameters; and (2) to determine optimal system parameter combinations when using the joint energy, maintenance, and production planning model. Additionally, a factor analysis on the system parameters is conducted and the corresponding performance of the production schedule under variable parameter conditions, is evaluated. Also, parameter optimization guidelines that incorporate maintenance and energy parameter decision making in the

  1. Refinery scheduling

    Energy Technology Data Exchange (ETDEWEB)

    Magalhaes, Marcus V.; Fraga, Eder T. [PETROBRAS, Rio de Janeiro, RJ (Brazil); Shah, Nilay [Imperial College, London (United Kingdom)

    2004-07-01

    This work addresses the refinery scheduling problem using mathematical programming techniques. The solution adopted was to decompose the entire refinery model into a crude oil scheduling and a product scheduling problem. The envelope for the crude oil scheduling problem is composed of a terminal, a pipeline and the crude area of a refinery, including the crude distillation units. The solution method adopted includes a decomposition technique based on the topology of the system. The envelope for the product scheduling comprises all tanks, process units and products found in a refinery. Once crude scheduling decisions are Also available the product scheduling is solved using a rolling horizon algorithm. All models were tested with real data from PETROBRAS' REFAP refinery, located in Canoas, Southern Brazil. (author)

  2. Decision Model for Planning and Scheduling of Seafood Product Considering Traceability

    Science.gov (United States)

    Agustin; Mawengkang, Herman; Mathelinea, Devy

    2018-01-01

    Due to the global challenges, it is necessary for an industrial company to integrate production scheduling and distribution planning, in order to be more efficient and to get more economics advantages. This paper presents seafood production planning and scheduling of a seafood manufacture company which produces simultaneously multi kind of seafood products, located at Aceh Province, Indonesia. The perishability nature of fish highly restricts its storage duration and delivery conditions. Traceability is a tracking requirement to check whether the quality of the product is satisfied. The production and distribution planning problem aims to meet customer demand subject to traceability of the seafood product and other restrictions. The problem is modeled as a mixed integer linear program, and then it is solved using neighborhood search approach.

  3. An FMS Dynamic Production Scheduling Algorithm Considering Cutting Tool Failure and Cutting Tool Life

    International Nuclear Information System (INIS)

    Setiawan, A; Wangsaputra, R; Halim, A H; Martawirya, Y Y

    2016-01-01

    This paper deals with Flexible Manufacturing System (FMS) production rescheduling due to unavailability of cutting tools caused either of cutting tool failure or life time limit. The FMS consists of parallel identical machines integrated with an automatic material handling system and it runs fully automatically. Each machine has a same cutting tool configuration that consists of different geometrical cutting tool types on each tool magazine. The job usually takes two stages. Each stage has sequential operations allocated to machines considering the cutting tool life. In the real situation, the cutting tool can fail before the cutting tool life is reached. The objective in this paper is to develop a dynamic scheduling algorithm when a cutting tool is broken during unmanned and a rescheduling needed. The algorithm consists of four steps. The first step is generating initial schedule, the second step is determination the cutting tool failure time, the third step is determination of system status at cutting tool failure time and the fourth step is the rescheduling for unfinished jobs. The approaches to solve the problem are complete-reactive scheduling and robust-proactive scheduling. The new schedules result differences starting time and completion time of each operations from the initial schedule. (paper)

  4. Analyzing Integrated Cost-Schedule Risk for Complex Product Systems R&D Projects

    Directory of Open Access Journals (Sweden)

    Zhe Xu

    2014-01-01

    Full Text Available The vast majority of the research efforts in project risk management tend to assess cost risk and schedule risk independently. However, project cost and time are related in reality and the relationship between them should be analyzed directly. We propose an integrated cost and schedule risk assessment model for complex product systems R&D projects. Graphical evaluation review technique (GERT, Monte Carlo simulation, and probability distribution theory are utilized to establish the model. In addition, statistical analysis and regression analysis techniques are employed to analyze simulation outputs. Finally, a complex product systems R&D project as an example is modeled by the proposed approach and the simulation outputs are analyzed to illustrate the effectiveness of the risk assessment model. It seems that integrating cost and schedule risk assessment can provide more reliable risk estimation results.

  5. 75 FR 15642 - Schedules of Controlled Substances: Exempted Prescription Product; River Edge Pharmaceutical...

    Science.gov (United States)

    2010-03-30

    ... 1117-AB28 Schedules of Controlled Substances: Exempted Prescription Product; River Edge Pharmaceutical... new applications for exemption. DEA has received one new application for exemption for River Edge... application for exemption pursuant to the provisions of 21 CFR 1308.32 for: River Edge Pharmaceutical's...

  6. Information Flow Scheduling in Concurrent Multi-Product Development Based on DSM

    Science.gov (United States)

    Sun, Qing-Chao; Huang, Wei-Qiang; Jiang, Ying-Jie; Sun, Wei

    2017-09-01

    Multi-product collaborative development is adopted widely in manufacturing enterprise, while the present multi-project planning models don't take technical/data interactions of multiple products into account. To decrease the influence of technical/data interactions on project progresses, the information flow scheduling models based on the extended DSM is presented. Firstly, information dependencies are divided into four types: series, parallel, coupling and similar. Secondly, different types of dependencies are expressed as DSM units, and the extended DSM model is brought forward, described as a block matrix. Furthermore, the information flow scheduling methods is proposed, which involves four types of operations, where partitioning and clustering algorithm are modified from DSM for ensuring progress of high-priority project, merging and converting is the specific computation of the extended DSM. Finally, the information flow scheduling of two machine tools development is analyzed with example, and different project priorities correspond to different task sequences and total coordination cost. The proposed methodology provides a detailed instruction for information flow scheduling in multi-product development, with specially concerning technical/data interactions.

  7. Comparative Simulation Study of Production Scheduling in the Hybrid and the Parallel Flow

    Directory of Open Access Journals (Sweden)

    Varela Maria L.R.

    2017-06-01

    Full Text Available Scheduling is one of the most important decisions in production control. An approach is proposed for supporting users to solve scheduling problems, by choosing the combination of physical manufacturing system configuration and the material handling system settings. The approach considers two alternative manufacturing scheduling configurations in a two stage product oriented manufacturing system, exploring the hybrid flow shop (HFS and the parallel flow shop (PFS environments. For illustrating the application of the proposed approach an industrial case from the automotive components industry is studied. The main aim of this research to compare results of study of production scheduling in the hybrid and the parallel flow, taking into account the makespan minimization criterion. Thus the HFS and the PFS performance is compared and analyzed, mainly in terms of the makespan, as the transportation times vary. The study shows that the performance HFS is clearly better when the work stations’ processing times are unbalanced, either in nature or as a consequence of the addition of transport times just to one of the work station processing time but loses advantage, becoming worse than the performance of the PFS configuration when the work stations’ processing times are balanced, either in nature or as a consequence of the addition of transport times added on the work stations’ processing times. This means that physical layout configurations along with the way transport time are including the work stations’ processing times should be carefully taken into consideration due to its influence on the performance reached by both HFS and PFS configurations.

  8. Proposed algorithm to improve job shop production scheduling using ant colony optimization method

    Science.gov (United States)

    Pakpahan, Eka KA; Kristina, Sonna; Setiawan, Ari

    2017-12-01

    This paper deals with the determination of job shop production schedule on an automatic environment. On this particular environment, machines and material handling system are integrated and controlled by a computer center where schedule were created and then used to dictate the movement of parts and the operations at each machine. This setting is usually designed to have an unmanned production process for a specified interval time. We consider here parts with various operations requirement. Each operation requires specific cutting tools. These parts are to be scheduled on machines each having identical capability, meaning that each machine is equipped with a similar set of cutting tools therefore is capable of processing any operation. The availability of a particular machine to process a particular operation is determined by the remaining life time of its cutting tools. We proposed an algorithm based on the ant colony optimization method and embedded them on matlab software to generate production schedule which minimize the total processing time of the parts (makespan). We test the algorithm on data provided by real industry and the process shows a very short computation time. This contributes a lot to the flexibility and timelines targeted on an automatic environment.

  9. Preventive Maintenance Scheduling for Multicogeneration Plants with Production Constraints Using Genetic Algorithms

    Directory of Open Access Journals (Sweden)

    Khaled Alhamad

    2015-01-01

    Full Text Available This paper describes a method developed to schedule the preventive maintenance tasks of the generation and desalination units in separate and linked cogeneration plants provided that all the necessary maintenance and production constraints are satisfied. The proposed methodology is used to generate two preventing maintenance schedules, one for electricity and the other for distiller. Two types of crossover operators were adopted, 2-point and 4-point. The objective function of the model is to maximize the available number of operational units in each plant. The results obtained were satisfying the problem parameters. However, 4-point slightly produce better solution than 2-point ones for both electricity and water distiller. The performance as well as the effectiveness of the genetic algorithm in solving preventive maintenance scheduling is applied and tested on a real system of 21 units for electricity and 21 units for water. The results presented here show a great potential for utility applications for effective energy management over a time horizon of 52 weeks. The model presented is an effective decision tool that optimizes the solution of the maintenance scheduling problem for cogeneration plants under maintenance and production constraints.

  10. Increasing the reliability of production schedules in a pharmaceutical packaging department.

    Science.gov (United States)

    Pacciarelli, Dario; D'Ariano, Andrea

    2012-12-01

    This paper studies quantitative methods for evaluating the potential benefits of introducing new advanced tracking technologies in the pharmaceutical industry with special reference to radio frequency identification (RFID). RFID technology is an effective way for increasing the quality of the data that are used to generate production schedules, but there is a lack of scientific research to quantify the return on investment that can be achieved in practice. In this work, we distinguish two major sources of data unreliability: one is the inherent stochasticity of operations, which cannot be reduced by RFID, and the other one is the data estimation error, which can be significantly reduced by RFID. We focus on the marginal contribution of the latter quantity to the productivity of the packaging department of a pharmaceutical plant, propose a systematic method for assessing this impact and discuss its implementation in a practical test case. Our results confirm that advanced tracking technologies in combination with effective scheduling procedures show a significant potential for improving productivity. Extensions to other production environments and their issues associated with scheduling problems are also discussed.

  11. Optimal scheduling for enhanced coal bed methane production through CO2 injection

    International Nuclear Information System (INIS)

    Huang, Yuping; Zheng, Qipeng P.; Fan, Neng; Aminian, Kashy

    2014-01-01

    Highlights: • A novel deterministic optimization model for CO 2 -ECBM production scheduling. • Maximize the total profit from both sales of natural gas and CO 2 credits trading in the carbon market. • A stochastic model incorporating uncertainties and dynamics of NG price and CO 2 credit. - Abstract: Enhanced coal bed methane production with CO 2 injection (CO 2 -ECBM) is an effective technology for accessing the natural gas embedded in the traditionally unmineable coal seams. The revenue via this production process is generated not only by the sales of coal bed methane, but also by trading CO 2 credits in the carbon market. As the technology of CO 2 -ECBM becomes mature, its commercialization opportunities are also springing up. This paper proposes applicable mathematical models for CO 2 -ECBM production and compares the impacts of their production schedules on the total profit. A novel basic deterministic model for CO 2 -ECBM production including the technical and chemical details is proposed and then a multistage stochastic programming model is formulated in order to address uncertainties of natural gas price and CO 2 credit. Both models are nonlinear programming problems, which are solved by commercial nonlinear programming software BARON via GAMS. Numerical experiments show the benefits (e.g., expected profit gain) of using stochastic models versus deterministic models

  12. 48 CFR 53.301-1427 - Standard Form 1427, Inventory Schedule A-Construction Sheet (Metals in Mill Product Form).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Standard Form 1427, Inventory Schedule A-Construction Sheet (Metals in Mill Product Form). 53.301-1427 Section 53.301-1427... Illustrations of Forms 53.301-1427 Standard Form 1427, Inventory Schedule A—Construction Sheet (Metals in Mill...

  13. Advances in mixed-integer programming methods for chemical production scheduling.

    Science.gov (United States)

    Velez, Sara; Maravelias, Christos T

    2014-01-01

    The goal of this paper is to critically review advances in the area of chemical production scheduling over the past three decades and then present two recently proposed solution methods that have led to dramatic computational enhancements. First, we present a general framework and problem classification and discuss modeling and solution methods with an emphasis on mixed-integer programming (MIP) techniques. Second, we present two solution methods: (a) a constraint propagation algorithm that allows us to compute parameters that are then used to tighten MIP scheduling models and (b) a reformulation that introduces new variables, thus leading to effective branching. We also present computational results and an example illustrating how these methods are implemented, as well as the resulting enhancements. We close with a discussion of open research challenges and future research directions.

  14. Scheduling the scheduling task : a time management perspective on scheduling

    NARCIS (Netherlands)

    Larco Martinelli, J.A.; Wiers, V.C.S.; Fransoo, J.C.

    2013-01-01

    Time is the most critical resource at the disposal of schedulers. Hence, an adequate management of time from the schedulers may impact positively on the scheduler’s productivity and responsiveness to uncertain scheduling environments. This paper presents a field study of how schedulers make use of

  15. An imperialist competitive algorithm for solving the production scheduling problem in open pit mine

    Directory of Open Access Journals (Sweden)

    Mojtaba Mokhtarian Asl

    2016-06-01

    Full Text Available Production scheduling (planning of an open-pit mine is the procedure during which the rock blocks are assigned to different production periods in a way that the highest net present value of the project achieved subject to operational constraints. The paper introduces a new and computationally less expensive meta-heuristic technique known as imperialist competitive algorithm (ICA for long-term production planning of open pit mines. The proposed algorithm modifies the original rules of the assimilation process. The ICA performance for different levels of the control factors has been studied and the results are presented. The result showed that ICA could be efficiently applied on mine production planning problem.

  16. Rework Impacts Evaluation Through System Dynamics Approach in Overlapped Product Development Schedule

    Directory of Open Access Journals (Sweden)

    Lino Guimarães Marujo

    2009-07-01

    Full Text Available This work aims to explore a novel framework to analyze the planning concepts in product development projects employing techniques to reduce the lead-time of activities, such as overlapping of a pair of each. With the System Dynamics methodology a model to evaluate the rework fraction needed to accommodate the deviations proportional to the overlapping grade of the activities. A numerical example is provided to demonstrate the validity of the model. Although problems encountered during the project management are dynamic, they have been treated on a static basis, what has as result, chronic schedules delays, overruns and cost overspent persist in follow the managers’ (reactions. In this work, we have addressed this known problem by introducing and reviewing some characteristics of the concept of rework in overlapped schedules. This consists in observe and capture the relations feedbacks among the original planned project schedule, the overlapping strategy and the inherent uncertainty in a work being done with poor information. To realize this concept, we have faced with many behaviors patterns (e.g. rework, new duration, non-conformity, and analyze the output behavior pattern, produced by the proposed model.

  17. The effect of the greek research reactor operating schedule on its fission product inventory

    International Nuclear Information System (INIS)

    Annousis, J.N., Armyriotis, J.S.

    1987-12-01

    A simple method to convert the fission product inventory of the 'Democritos' uous Greek Research Reactor (GRR) corresponding to its continuous operation over a given time interval, into the inventory corresponting to GRR discontinuous but periodic operation of the same total duration, is presented in this paper. Relevant correction factors for 31 radioecologically significant radionuclides of the inventory are given as a function of the number of hours or operation per day, 5 days per week of the GRR, according to its present of possible future operating schedule

  18. The effect of the Greek Research Reactor operating schedule on its fission product inventory

    International Nuclear Information System (INIS)

    ANOUSSIS, J.N.; ARMYRIOTIS, J.S.

    1987-12-01

    Full text:A simple method to convert the fission product inventory of ''Demokritos'' Greek Research Reactor(GRR) corresponding to its continuous operation over a given time interval, into the inventory corresponding to GRR discontinuous but periodic operation of the same total duration, is presented in this paper. Relevant correction factors for 31 radioecologically significant radionuclides of the inventory are given as a function of the number of hours of operation per day, 5 days per week of the GRR, according to its present or possible future operating schedule. (author)

  19. Optimal Research and Numerical Simulation for Scheduling No-Wait Flow Shop in Steel Production

    Directory of Open Access Journals (Sweden)

    Huawei Yuan

    2013-01-01

    Full Text Available This paper considers the m-machine flow shop scheduling problem with the no-wait constraint to minimize total completion time which is the typical model in steel production. First, the asymptotic optimality of the Shortest Processing Time (SPT first rule is proven for this problem. To further evaluate the performance of the algorithm, a new lower bound with performance guarantee is designed. At the end of the paper, numerical simulations show the effectiveness of the proposed algorithm and lower bound.

  20. Off-Line and Dynamic Production Scheduling – A Comparative Case Study

    OpenAIRE

    Bożek Andrzej; Wysocki Marian

    2016-01-01

    A comprehensive case study of manufacturing scheduling solutions development is given. It includes highly generalized scheduling problem as well as a few scheduling modes, methods and problem models. The considered problem combines flexible job shop structure, lot streaming with variable sublots, transport times, setup times, and machine calendars. Tabu search metaheuristic and constraint programming methods have been used for the off-line scheduling. Two dynamic scheduling methods have also ...

  1. Stability measures for rolling schedules with applications to capacity expansion planning, master production scheduling, and lot sizing

    OpenAIRE

    Kimms, Alf

    1996-01-01

    This contribution discusses the measurement of (in-)stability of finite horizon production planning when done on a rolling horizon basis. As examples we review strategic capacity expansion planning, tactical master production schedulng, and operational capacitated lot sizing.

  2. REORGANIZATION OF THE TECHNOLOGICAL FLOW AT CLOTHING COMPANY THROUGH THE PRODUCTION SCHEDULE

    Directory of Open Access Journals (Sweden)

    GHELBET Angela

    2017-05-01

    Full Text Available One of the main difficulties that light industry, namely clothing manufacturing sector faces today is inadequate organization of production processes. This is one of the most common and most serious obstacles in companies in the country, leading to low productivity. In order to reveal the causes of the problem and to develop solutions for change, it is proposed to conduct a study of a company facing difficulties in organizing the production process. It is important that the method/tool applied for the study is able to solve the problems occurring in the production process with minimum effort and maximum efficiency. The study was conducted within the process of manufacturing of a model of special clothing, namely clothing for doctors. The study was conducted within February-March 2016 at a clothing company of the Republic of Moldova. The study conducted shows that the transport issue in the technological flow can be solved by applying the production schedule, which eventually increases labor productivity by eliminating the time necessary to transport the labor object from one place of work to another, leading to economic growth considerable for the company. Following the assessments referring to the proposed improvements to organize the technological flow, there should be a 20% reduction in manufacturing time of a product, which will directly increase the revenue of the company by at least 10%.

  3. The importance of interpreting the commercial contract in scheduling the production of a Romanian business operator

    Directory of Open Access Journals (Sweden)

    Laura MUREŞAN (POŢINCU

    2015-12-01

    Full Text Available Part of scheduling the production is complying with the conditions of the commercial contract, which is the foundation of the relation between the client and the business operator that performs its activity in the area of the industrial production. In case the compliance with the contractual obligations raises issues, it is required to interpret the commercial contract according to the provisions of the Romanian Civil Code. This work aims at presenting and analyzing these rules of interpreting the commercial contract, which are not provided in the special stipulations of the law applied to the business field, so that one shall consider the rules common to the private law, i.e. the juridical norms provided by the legislation of the civil law.

  4. The bases for optimisation of scheduled repairs and tests of safety systems to improve the NPP productive efficiency

    International Nuclear Information System (INIS)

    Bilej, D.V.; Vasil'chenko, S.V.; Vlasenko, N.I.; Vasil'chenko, V.N.; Skalozubov, V.I.

    2004-01-01

    In the frames of risk-informed approaches the paper proposed the theoretical bases for methods of optimisation of scheduled repairs and tests of safety systems at nuclear power plants. The optimisation criterion is the objective risk function minimising. This function depends on the scheduled repairs/tests periodicity and the allowed time to bring the system channel to a state of non-operability. The main optimisation direct is to reduce the repair time with the purpose of enhancement of productive efficiency

  5. A hybrid flow shop model for an ice cream production scheduling problem

    Directory of Open Access Journals (Sweden)

    Imma Ribas Vila

    2009-07-01

    Full Text Available Normal 0 21 false false false ES X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Taula normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} In this paper we address the scheduling problem that comes from an ice cream manufacturing company. This production system can be modelled as a three stage nowait hybrid flow shop with batch dependent setup costs. To contribute reducing the gap between theory and practice we have considered the real constraints and the criteria used by planners. The problem considered has been formulated as a mixed integer programming. Further, two competitive heuristic procedures have been developed and one of them will be proposed to schedule in the ice cream factory.

  6. Multi-Agent Based Beam Search for Real-Time Production Scheduling and Control Method, Software and Industrial Application

    CERN Document Server

    Kang, Shu Gang

    2013-01-01

    The Multi-Agent Based Beam Search (MABBS) method systematically integrates four major requirements of manufacturing production - representation capability, solution quality, computation efficiency, and implementation difficulty - within a unified framework to deal with the many challenges of complex real-world production planning and scheduling problems. Multi-agent Based Beam Search for Real-time Production Scheduling and Control introduces this method, together with its software implementation and industrial applications.  This book connects academic research with industrial practice, and develops a practical solution to production planning and scheduling problems. To simplify implementation, a reusable software platform is developed to build the MABBS method into a generic computation engine.  This engine is integrated with a script language, called the Embedded Extensible Application Script Language (EXASL), to provide a flexible and straightforward approach to representing complex real-world problems. ...

  7. A random-key encoded harmony search approach for energy-efficient production scheduling with shared resources

    Science.gov (United States)

    Garcia-Santiago, C. A.; Del Ser, J.; Upton, C.; Quilligan, F.; Gil-Lopez, S.; Salcedo-Sanz, S.

    2015-11-01

    When seeking near-optimal solutions for complex scheduling problems, meta-heuristics demonstrate good performance with affordable computational effort. This has resulted in a gravitation towards these approaches when researching industrial use-cases such as energy-efficient production planning. However, much of the previous research makes assumptions about softer constraints that affect planning strategies and about how human planners interact with the algorithm in a live production environment. This article describes a job-shop problem that focuses on minimizing energy consumption across a production facility of shared resources. The application scenario is based on real facilities made available by the Irish Center for Manufacturing Research. The formulated problem is tackled via harmony search heuristics with random keys encoding. Simulation results are compared to a genetic algorithm, a simulated annealing approach and a first-come-first-served scheduling. The superior performance obtained by the proposed scheduler paves the way towards its practical implementation over industrial production chains.

  8. Capacity optimization and scheduling of a multiproduct manufacturing facility for biotech products.

    Science.gov (United States)

    Shaik, Munawar A; Dhakre, Ankita; Rathore, Anurag S; Patil, Nitin

    2014-01-01

    A general mathematical framework has been proposed in this work for scheduling of a multiproduct and multipurpose facility involving manufacturing of biotech products. The specific problem involves several batch operations occurring in multiple units involving fixed processing time, unlimited storage policy, transition times, shared units, and deterministic and fixed data in the given time horizon. The different batch operations are modeled using state-task network representation. Two different mathematical formulations are proposed based on discrete- and continuous-time representations leading to a mixed-integer linear programming model which is solved using General Algebraic Modeling System software. A case study based on a real facility is presented to illustrate the potential and applicability of the proposed models. The continuous-time model required less number of events and has a smaller problem size compared to the discrete-time model. © 2014 American Institute of Chemical Engineers.

  9. Integrated Scheduling of Production and Distribution with Release Dates and Capacitated Deliveries

    Directory of Open Access Journals (Sweden)

    Xueling Zhong

    2016-01-01

    Full Text Available This paper investigates an integrated scheduling of production and distribution model in a supply chain consisting of a single machine, a customer, and a sufficient number of homogeneous capacitated vehicles. In this model, the customer places a set of orders, each of which has a given release date. All orders are first processed nonpreemptively on the machine and then batch delivered to the customer. Two variations of the model with different objective functions are studied: one is to minimize the arrival time of the last order plus total distribution cost and the other is to minimize total arrival time of the orders plus total distribution cost. For the former one, we provide a polynomial-time exact algorithm. For the latter one, due to its NP-hard property, we provide a heuristic with a worst-case ratio bound of 2.

  10. 77 FR 31877 - Corrosion-Resistant Carbon Steel Flat Products From Germany and Korea; Scheduling of Full Five...

    Science.gov (United States)

    2012-05-30

    ... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 701-TA-350 and 731-TA-616 and 618 (Third Review)] Corrosion-Resistant Carbon Steel Flat Products From Germany and Korea; Scheduling of Full Five-Year Reviews... corrosion-resistant carbon steel flat products from Korea and the antidumping duty orders on corrosion...

  11. Off-Line and Dynamic Production Scheduling – A Comparative Case Study

    Directory of Open Access Journals (Sweden)

    Bożek Andrzej

    2016-03-01

    Full Text Available A comprehensive case study of manufacturing scheduling solutions development is given. It includes highly generalized scheduling problem as well as a few scheduling modes, methods and problem models. The considered problem combines flexible job shop structure, lot streaming with variable sublots, transport times, setup times, and machine calendars. Tabu search metaheuristic and constraint programming methods have been used for the off-line scheduling. Two dynamic scheduling methods have also been implemented, i.e., dispatching rules for the completely reactive scheduling and a multi-agent system for the predictivereactive scheduling. In these implementations three distinct models of the problem have been used, based on: graph representation, optimal constraint satisfaction, and Petri net formalism. Each of these solutions has been verified in computational experiments. The results are compared and some findings about advantages, disadvantages, and suggestions on using the solutions are formulated.

  12. Implementation of quality assurance with respect to product quality and scheduling

    International Nuclear Information System (INIS)

    Schleimer, W.F.

    1986-04-01

    Quality assurance means the whole range of actions which are necessary to meet the client's requirements for the product and the test methods. Audits: The preconditions for fabrication must be fulfilled by approval of the manufacturer's quality assurance system, the staff's qualification, his procedures and his equipments. This is done by means of a system audit at KWU or an equivalent organisation. Specifications: For quality assurance the requirements for the components are fixed in specifications. There are material specifications, process/procedure specifications, components specifications. Approval of Component Design and Manufacture (Scheduling): The approval procedure of a structurally welded part is described as an example of the approval of component design and manufacture, thus representing one small piece of a mechanical equipment. In-Process Surveillance (Product Audit): At KWU the in-process surveillance is regulated by a KQ- or product audit concept. In this concept we have K- and KQ-steps. The list of KQ-steps will be presented. Documentation: All test or examination steps are documented with certificates, lists, and stamps for the final documentation. 19 figs

  13. Production scheduling of a lignite mine under quality and reserves uncertainty

    International Nuclear Information System (INIS)

    Galetakis, Michael; Roumpos, Christos; Alevizos, George; Vamvuka, Despina

    2011-01-01

    The effect of uncertainty sources to the stochastic optimization of the combined project of a new surface lignite mine exploitation and power plant operation for electricity generation is investigated. Major sources of uncertainty that were considered are the reserves and the quality of the lignite. Since probability distribution functions for these uncertainties were estimated during the detailed exploration phase of the deposit, the overall goal is then to determine the optimal capacity of the power plant and consequently the optimal production rate of the mine over the time. The optimization objective that was selected is the maximization of the net present value of the project. Emphasis is placed on the sensitivity analysis for the investigation of the effect of quality and reserves uncertainty on project optimization, on the mathematical formulation of risk attitude strategy and on increasing the efficiency of the optimization process by creating a limited set of feasible solutions applying empirical rules. The developed methodology was applied for the determination of the optimal annual production rate of a new surface lignite mine in the area of Ptolemais–Amynteon in Northern Greece. - Highlights: ► Quality and reserves uncertainty affects considerably the production scheduling. ► Stochastic optimization is greatly accelerated by incorporating Taylor's rule. ► Decisions can be made considering different risk level attitudes.

  14. Reprint of: Production scheduling of a lignite mine under quality and reserves uncertainty

    International Nuclear Information System (INIS)

    Galetakis, Michael; Roumpos, Christos; Alevizos, George; Vamvuka, Despina

    2012-01-01

    The effect of uncertainty sources to the stochastic optimization of the combined project of a new surface lignite mine exploitation and power plant operation for electricity generation is investigated. Major sources of uncertainty that were considered are the reserves and the quality of the lignite. Since probability distribution functions for these uncertainties were estimated during the detailed exploration phase of the deposit, the overall goal is then to determine the optimal capacity of the power plant and consequently the optimal production rate of the mine over the time. The optimization objective that was selected is the maximization of the net present value of the project. Emphasis is placed on the sensitivity analysis for the investigation of the effect of quality and reserves uncertainty on project optimization, on the mathematical formulation of risk attitude strategy and on increasing the efficiency of the optimization process by creating a limited set of feasible solutions applying empirical rules. The developed methodology was applied for the determination of the optimal annual production rate of a new surface lignite mine in the area of Ptolemais–Amynteon in Northern Greece. - Highlights: ► Quality and reserves uncertainty affects considerably the production scheduling. ► Stochastic optimization is greatly accelerated by incorporating Taylor's rule. ► Decisions can be made considering different risk level attitudes.

  15. Project scheduling with resources constraints: application in the equipment production for the oil industry; Scheduling de projetos com restricao de recursos: aplicacao na producao de equipamentos para a industria de petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Cruz, Carolina A.O.; Ferreira Filho, Virgilio J.M. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia (COPPE)

    2008-07-01

    One of the essential steps in the main scope Project Management is the Time Management made by the planning and control of the project schedule. In this work is presented the resource constrained scheduling problem beyond its mathematical formulation and a review of papers about this issue. In sequence is presented a practical example of this model considering a simplified model of an engineering project schedule of oil production equipment. The results obtained with the model application are shown and the conclusions about the work with resource constrained scheduling problems. (author)

  16. Freezing issue on stability master production scheduling for supplier network: Decision making view

    Directory of Open Access Journals (Sweden)

    Aisyati Azizah

    2017-01-01

    Full Text Available In the daily operation, there are frequently changes in customer order requirement which will induce instability of the MPS. Moreover, the frequently adjustment of MPS can induce fluctuation of production and increasing of inventory cost as well as decreasing service level of customer. Most of studies about instability of MPS use freezing method and rolling procedure to adjust MPS periodically. Freezing is the proportion of planning horizon being frozen, whereas rolling procedure is a method replanning periodically of MPS using newly updated demand data. This study is focused on interval freezing length as an issue of decision making. In supply chain, a manufacturer is supported by suppliers to supply material requirement. Since a manufacturer plan production schedule on MPS the freezing interval is determined that will be informed to suppliers which supply the material requirement. In previous research, the freezing interval is decided by manufacturer as necessary decision maker. This decision must be followed by suppliers though it is not beneficial for them. It can be concluded that this condition is no win-win situation. Hence, this research proposes that suppliers will be involved as decision maker besides a manufacturer so the interval freezing is decided by two-side decision maker.

  17. Multiobjective Joint Optimization of Production Scheduling and Maintenance Planning in the Flexible Job-Shop Problem

    Directory of Open Access Journals (Sweden)

    Jianfei Ye

    2015-01-01

    Full Text Available In order to solve the joint optimization of production scheduling and maintenance planning problem in the flexible job-shop, a multiobjective joint optimization model considering the maximum completion time and maintenance costs per unit time is established based on the concept of flexible job-shop and preventive maintenance. A weighted sum method is adopted to eliminate the index dimension. In addition, a double-coded genetic algorithm is designed according to the problem characteristics. The best result under the circumstances of joint decision-making is obtained through multiple simulation experiments, which proves the validity of the algorithm. We can prove the superiority of joint optimization model by comparing the result of joint decision-making project with the result of independent decision-making project under fixed preventive maintenance period. This study will enrich and expand the theoretical framework and analytical methods of this problem; it provides a scientific decision analysis method for enterprise to make production plan and maintenance plan.

  18. 77 FR 67395 - Corrosion-Resistant Carbon Steel Flat Products From Germany and Korea; Revised Schedule for the...

    Science.gov (United States)

    2012-11-09

    ... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 701-TA-350 and 731-TA-616 and 618 (Third Review)] Corrosion-Resistant Carbon Steel Flat Products From Germany and Korea; Revised Schedule for the Subject Reviews AGENCY: United States International Trade Commission. ACTION: Notice. DATES: Effective Date...

  19. Ensemble hydro-meteorological forecasting for early warning of floods and scheduling of hydropower production

    Science.gov (United States)

    Solvang Johansen, Stian; Steinsland, Ingelin; Engeland, Kolbjørn

    2016-04-01

    Running hydrological models with precipitation and temperature ensemble forcing to generate ensembles of streamflow is a commonly used method in operational hydrology. Evaluations of streamflow ensembles have however revealed that the ensembles are biased with respect to both mean and spread. Thus postprocessing of the ensembles is needed in order to improve the forecast skill. The aims of this study is (i) to to evaluate how postprocessing of streamflow ensembles works for Norwegian catchments within different hydrological regimes and to (ii) demonstrate how post processed streamflow ensembles are used operationally by a hydropower producer. These aims were achieved by postprocessing forecasted daily discharge for 10 lead-times for 20 catchments in Norway by using EPS forcing from ECMWF applied the semi-distributed HBV-model dividing each catchment into 10 elevation zones. Statkraft Energi uses forecasts from these catchments for scheduling hydropower production. The catchments represent different hydrological regimes. Some catchments have stable winter condition with winter low flow and a major flood event during spring or early summer caused by snow melting. Others has a more mixed snow-rain regime, often with a secondary flood season during autumn, and in the coastal areas, the stream flow is dominated by rain, and the main flood season is autumn and winter. For post processing, a Bayesian model averaging model (BMA) close to (Kleiber et al 2011) is used. The model creates a predictive PDF that is a weighted average of PDFs centered on the individual bias corrected forecasts. The weights are here equal since all ensemble members come from the same model, and thus have the same probability. For modeling streamflow, the gamma distribution is chosen as a predictive PDF. The bias correction parameters and the PDF parameters are estimated using a 30-day sliding window training period. Preliminary results show that the improvement varies between catchments depending

  20. A genetic algorithm approach for open-pit mine production scheduling

    Directory of Open Access Journals (Sweden)

    Aref Alipour

    2017-06-01

    Full Text Available In an Open-Pit Production Scheduling (OPPS problem, the goal is to determine the mining sequence of an orebody as a block model. In this article, linear programing formulation is used to aim this goal. OPPS problem is known as an NP-hard problem, so an exact mathematical model cannot be applied to solve in the real state. Genetic Algorithm (GA is a well-known member of evolutionary algorithms that widely are utilized to solve NP-hard problems. Herein, GA is implemented in a hypothetical Two-Dimensional (2D copper orebody model. The orebody is featured as two-dimensional (2D array of blocks. Likewise, counterpart 2D GA array was used to represent the OPPS problem’s solution space. Thereupon, the fitness function is defined according to the OPPS problem’s objective function to assess the solution domain. Also, new normalization method was used for the handling of block sequencing constraint. A numerical study is performed to compare the solutions of the exact and GA-based methods. It is shown that the gap between GA and the optimal solution by the exact method is less than % 5; hereupon GA is found to be efficiently in solving OPPS problem.

  1. Schedules of Controlled Substances: Placement of FDA-Approved Products of Oral Solutions Containing Dronabinol [(-)-delta-9-trans-

    Science.gov (United States)

    2017-11-22

    This final rule adopts without changes an interim final rule with request for comments published in the Federal Register on March 23, 2017. On July 1, 2016, the U.S. Food and Drug Administration (FDA) approved a new drug application for Syndros, a drug product consisting of dronabinol [(-)-delta-9-trans-tetrahydrocannabinol (delta-9-THC)] oral solution. The Drug Enforcement Administration (DEA) maintains FDA-approved products of oral solutions containing dronabinol in schedule II of the Controlled Substances Act.

  2. Sustainable Scheduling of Cloth Production Processes by Multi-Objective Genetic Algorithm with Tabu-Enhanced Local Search

    Directory of Open Access Journals (Sweden)

    Rui Zhang

    2017-09-01

    Full Text Available The dyeing of textile materials is the most critical process in cloth production because of the strict technological requirements. In addition to the technical aspect, there have been increasing concerns over how to minimize the negative environmental impact of the dyeing industry. The emissions of pollutants are mainly caused by frequent cleaning operations which are necessary for initializing the dyeing equipment, as well as idled production capacity which leads to discharge of unconsumed chemicals. Motivated by these facts, we propose a methodology to reduce the pollutant emissions by means of systematic production scheduling. Firstly, we build a three-objective scheduling model that incorporates both the traditional tardiness objective and the environmentally-related objectives. A mixed-integer programming formulation is also provided to accurately define the problem. Then, we present a novel solution method for the sustainable scheduling problem, namely, a multi-objective genetic algorithm with tabu-enhanced iterated greedy local search strategy (MOGA-TIG. Finally, we conduct extensive computational experiments to investigate the actual performance of the MOGA-TIG. Based on a fair comparison with two state-of-the-art multi-objective optimizers, it is concluded that the MOGA-TIG is able to achieve satisfactory solution quality within tight computational time budget for the studied scheduling problem.

  3. Optimal Scheduling of Material Handling Devices in a PCB Production Line: Problem Formulation and a Polynomial Algorithm

    Directory of Open Access Journals (Sweden)

    Ada Che

    2008-01-01

    Full Text Available Modern automated production lines usually use one or multiple computer-controlled robots or hoists for material handling between workstations. A typical application of such lines is an automated electroplating line for processing printed circuit boards (PCBs. In these systems, cyclic production policy is widely used due to large lot size and simplicity of implementation. This paper addresses cyclic scheduling of a multihoist electroplating line with constant processing times. The objective is to minimize the cycle time, or equivalently to maximize the production throughput, for a given number of hoists. We propose a mathematical model and a polynomial algorithm for this scheduling problem. Computational results on randomly generated instances are reported.

  4. Hypofractionated Breast Radiation: Shorter Scheme, Lower Toxicity.

    Science.gov (United States)

    Linares, Isabel; Tovar, María Isabel; Zurita, Mercedes; Guerrero, Rosario; Expósito, Manuela; Del Moral, Rosario

    2016-08-01

    We analyzed the toxicity and cosmetic outcomes for patients who had undergone 3-dimensional conformal radiotherapy with a hypofractionated schedule and identified the risk factors associated with such a schedule. A total of 143 patients were treated for breast cancer (stage 0-III) with a hypofractionated radiation schedule after breast-conserving surgery from 2006 to 2011. Most patients received 42.4 Gy in 16 daily fractions, 2.65 Gy per fraction to the whole breast plus an additional simultaneous integrated or sequential boost to the tumor bed. The median follow-up period was 36 months. Mild acute skin toxicity was observed in 62%; 7% of the patients developed moderate skin toxicity, but no grade 4 toxicity was observed. The prevalence of fibrosis within the boost area was 5%, but no grade ≥ 2 was observed. The prevalence of fibrosis of any grade was greater in the nonboost (23%) than in the boost area. Of all the patients, 91% had good or excellent cosmetic outcomes. From the multivariate analysis, the incidence of epithelitis correlated with the patient's treated volume (P = .044). The incidence of acute toxicity correlated with the boost type to the tumor bed and the total treatment dose (P = .012 and P = .002, respectively). Also, a poor to fair cosmetic outcome was significantly associated statistically with the surgery type (P = .05), boost type (P = .004), and total dose (P = .001). Delivering whole-breast irradiation with a hypofractionated schedule of 42.4 Gy plus a simultaneous integrated boost to the tumor bed appears to be a safe and effective technique, with good cosmetic results and lower toxicity. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Developing a versatile simulation, scheduling and economic model framework for bioenergy production systems

    Directory of Open Access Journals (Sweden)

    Robert Matindi

    2019-01-01

    Full Text Available Modelling is an effective way of designing, understanding, and analysing bio-refinery supply chain systems. The supply chain is a complex process consisting of many systems interacting with each other. It requires the modelling of the processes in the presence of multiple autonomous entities (i.e. biomass producers, bio-processors and transporters, multiple performance measures and multiple objectives, both local and global, which together constitute very complex interaction effects. In this paper, simulation models for recovering biomass from the field of the biorefinery are developed and validated using some industry data and the minimum biomass recovery cost is established based on different strategies employed for recovering biomass. Energy densification techniques are evaluated for their net present worth and the technologies that offer greater returns for the industry are recommended. In addition, a new scheduling algorithm is also developed to enhance the process flow of the management of resources and the flow of biomass. The primary objective is to investigate different strategies to reach the lowest cost delivery of sugarcane harvest residue to a sugar factory through optimally located bio-refineries. A simulation /optimisation solution approach is also developed to tackle the stochastic variables in the bioenergy production system based on different statistical distributions such as Weibull and Pearson distributions. In this approach, a genetic algorithm is integrated with simulation to improve the initial solution and search the near-optimal solution. A case study is conducted to illustrate the results and to validate the applicability for the real world implementation using ExtendSIM Simulation software using some real data from Australian Mills.

  6. Optimal production scheduling for energy efficiency improvement in biofuel feedstock preprocessing considering work-in-process particle separation

    International Nuclear Information System (INIS)

    Li, Lin; Sun, Zeyi; Yao, Xufeng; Wang, Donghai

    2016-01-01

    Biofuel is considered a promising alternative to traditional liquid transportation fuels. The large-scale substitution of biofuel can greatly enhance global energy security and mitigate greenhouse gas emissions. One major concern of the broad adoption of biofuel is the intensive energy consumption in biofuel manufacturing. This paper focuses on the energy efficiency improvement of biofuel feedstock preprocessing, a major process of cellulosic biofuel manufacturing. An improved scheme of the feedstock preprocessing considering work-in-process particle separation is introduced to reduce energy waste and improve energy efficiency. A scheduling model based on the improved scheme is also developed to identify an optimal production schedule that can minimize the energy consumption of the feedstock preprocessing under production target constraint. A numerical case study is used to illustrate the effectiveness of the proposed method. The research outcome is expected to improve the energy efficiency and enhance the environmental sustainability of biomass feedstock preprocessing. - Highlights: • A novel method to schedule production in biofuel feedstock preprocessing process. • Systems modeling approach is used. • Capable of optimize preprocessing to reduce energy waste and improve energy efficiency. • A numerical case is used to illustrate the effectiveness of the method. • Energy consumption per unit production can be significantly reduced.

  7. Integrated batch production and maintenance scheduling for multiple items processed on a deteriorating machine to minimize total production and maintenance costs with due date constraint

    Directory of Open Access Journals (Sweden)

    Zahedi Zahedi

    2016-04-01

    Full Text Available This paper discusses an integrated model of batch production and maintenance scheduling on a deteriorating machine producing multiple items to be delivered at a common due date. The model describes the trade-off between total inventory cost and maintenance cost as the increase of production run length. The production run length is a time bucket between two consecutive preventive maintenance activities. The objective function of the model is to minimize total cost consisting of in process and completed part inventory costs, setup cost, preventive and corrective maintenance costs and rework cost. The problem is to determine the optimal production run length and to schedule the batches obtained from determining the production run length in order to minimize total cost.

  8. A Three-Stage Optimization Algorithm for the Stochastic Parallel Machine Scheduling Problem with Adjustable Production Rates

    Directory of Open Access Journals (Sweden)

    Rui Zhang

    2013-01-01

    Full Text Available We consider a parallel machine scheduling problem with random processing/setup times and adjustable production rates. The objective functions to be minimized consist of two parts; the first part is related with the due date performance (i.e., the tardiness of the jobs, while the second part is related with the setting of machine speeds. Therefore, the decision variables include both the production schedule (sequences of jobs and the production rate of each machine. The optimization process, however, is significantly complicated by the stochastic factors in the manufacturing system. To address the difficulty, a simulation-based three-stage optimization framework is presented in this paper for high-quality robust solutions to the integrated scheduling problem. The first stage (crude optimization is featured by the ordinal optimization theory, the second stage (finer optimization is implemented with a metaheuristic called differential evolution, and the third stage (fine-tuning is characterized by a perturbation-based local search. Finally, computational experiments are conducted to verify the effectiveness of the proposed approach. Sensitivity analysis and practical implications are also discussed.

  9. Production Scheduling in Complex Job Shops from an Industrie 4.0 Perspective: A Review and Challenges in the Semiconductor Industry

    OpenAIRE

    Waschneck, Bernd; Bauernhansl, Thomas; Altenmüller, Thomas; Kyek, Andreas

    2017-01-01

    On the one hand, Industrie 4.0 has recently emerged as the keyword for increasing productivity in the 21st century. On the other hand, production scheduling in a Complex Job Shop (CJS) environment, such as wafer fabrication facilities, has drawn interest of researchers dating back to the 1950s [65, 18]. Although both research areas overlap, there seems to be very little interchange of ideas. This review presents and assesses production scheduling techniques in complex job shops from an Indust...

  10. Implications of shorter cells in PEP

    International Nuclear Information System (INIS)

    Wiedemann, H.

    1975-01-01

    Further studies on the beam-stay-clear requirements in PEP led to the conclusion that the vertical aperture needed to be enlarged. There are two main reasons for that: Observations at SPEAR indicate that the aperture should be large enough for a fully coupled beam. Full coupling of the horizontal and vertical betatron oscillations occurs not only occasionally when the energy, tune or betatron function at the interaction point is changed but also due to the beam/endash/beam effect of two strong colliding beams. The second reason for an increased aperture requirement is the nonlinear perturbation of the particle trajectories by the sextupoles. This perturbation increases a fully coupled beam by another 50% to 80%. Both effects together with a +-5 mm allowance for closed orbit perturbation result in a vertical beam-stay-clear in the bending magnets of +-4.8 to +-5.6 cm, compared to the present +-2.0 cm. This beam-stay-clear, together with additional space for vacuum chamber, etc., leads to very costly bending magnets. In this note, a shorter cell length is proposed which would reduce considerably the vertical beam-stay-clear requirements in the bending magnets. 7 figs

  11. Variable demand and productivity in diagnostic medicine: the customer experience with the scheduling of examinations

    Directory of Open Access Journals (Sweden)

    Leandro Ortigoza Martins

    2016-04-01

    Full Text Available From the perspective of marketing, diagnostic medicine services are perishable and demand is variable — characteristics that difficult the maximization of results. Service providers offer the exams through time scheduling system without, however, overcome the inefficiency caused by the no show customers. The objective of this research was to investigate the level of satisfaction of consumers of diagnostic medicine with the schedule, the acceptance of a new model without an appointment time and analyze three secondary dimensions common to the two models (no show, seasonality and timeout in customer satisfaction. This is a quantitative research with exploratory-descriptive design performed with 2,545 clients from a privately held diagnostic medicine in 2013. The results of the secondary dimensions indicated that customers tend to frequent establishments as the current seasonal and are sensitive to wait. As for the main dimensions (scheduling and demand free, there are different levels of acceptance, indicating that the two systems are complementary and not exclusive and therefore, the feasibility of adopting a hybrid model of operation, with the use of two templates.

  12. A Novel Strategy Using Factor Graphs and the Sum-Product Algorithm for Satellite Broadcast Scheduling Problems

    Science.gov (United States)

    Chen, Jung-Chieh

    This paper presents a low complexity algorithmic framework for finding a broadcasting schedule in a low-altitude satellite system, i. e., the satellite broadcast scheduling (SBS) problem, based on the recent modeling and computational methodology of factor graphs. Inspired by the huge success of the low density parity check (LDPC) codes in the field of error control coding, in this paper, we transform the SBS problem into an LDPC-like problem through a factor graph instead of using the conventional neural network approaches to solve the SBS problem. Based on a factor graph framework, the soft-information, describing the probability that each satellite will broadcast information to a terminal at a specific time slot, is exchanged among the local processing in the proposed framework via the sum-product algorithm to iteratively optimize the satellite broadcasting schedule. Numerical results show that the proposed approach not only can obtain optimal solution but also enjoys the low complexity suitable for integral-circuit implementation.

  13. Schedules of Controlled Substances: Placement of FDA-Approved Products of Oral Solutions Containing Dronabinol [(-)-delta-9-transtetrahydrocannabinol (delta-9-THC)] in Schedule II. Interim final rule, with request for comments.

    Science.gov (United States)

    2017-03-23

    On July 1, 2016, the U.S. Food and Drug Administration (FDA) approved a new drug application for Syndros, a drug product consisting of dronabinol [(-)-delta-9-trans-tetrahydrocannabinol (delta-9-THC)] oral solution. Thereafter, the Department of Health and Human Services (HHS) provided the Drug Enforcement Administration (DEA) with a scheduling recommendation that would result in Syndros (and other oral solutions containing dronabinol) being placed in schedule II of the Controlled Substances Act (CSA). In accordance with the CSA, as revised by the Improving Regulatory Transparency for New Medical Therapies Act, DEA is hereby issuing an interim final rule placing FDA-approved products of oral solutions containing dronabinol in schedule II of the CSA.

  14. A Review of Just-In-Time Scheduling for Production and Logistics

    OpenAIRE

    田村, 隆善

    1999-01-01

    The Just-In-Time (JIT) production has been developed as a subsystem of the "whole" Toyota production system (TPS). Currently JIT or JIT production means the TPS especially in foreign countries. It is recognized that JIT is a key concept for enterprises competing in the diversified-products market. The technologies used in JIT are comprehensive and include technologies to design, install and control a production system, which are classified into three categories : hardware, information and sof...

  15. Decentralized scheduling algorithm to improve the rate of production without increasing the stocks of intermediates; Zaiko wo fuyasu kotonaku seisan sokudo wo kojo saseru jiritsu bunsangata sukejuringu arugorizumu

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Kazuhiro; Shiigi, Daisuke; Tsuge, Yoshifumi; Matsuyama, Hisayoshi [Kyushu University, Fukuoka (Japan). Department of Chemical Engineering

    1999-03-10

    In a factory with a multi-stage production system, push-type scheduling methods can hardly improve the production rate without increasing the stocks of intermediates. For products whose specifications are known before their orders, a pull-type scheduling method named Kanban system has been developed, and has succeeded to improve the production rate without increasing the stocks of intermediates. The Kanban system, however, is not applicable to custom-made products whose specifications are not known before their orders. In this paper, a 'Virtual Kanban (VK) system' is presented as a pull-type scheduling method which is applicable to custom-made products, and its usefulness is demonstrated by simulation of an application specific integrated circuit manufacturing facility. (author)

  16. Reactor outage schedule (tentative)

    Energy Technology Data Exchange (ETDEWEB)

    Walton, R.P.

    1969-11-01

    This single page document is the November 1, 1969 reactor refueling outage schedule for the Hanford Production Reactor. It also contains data on the amounts and types of fuels to be loaded and relocated in the production reactor.

  17. Reactor outage schedule (tentative)

    Energy Technology Data Exchange (ETDEWEB)

    Walton, R.P.

    1969-10-01

    This single page document is the October 1, 1969 reactor refueling outage schedule for the Hanford Production Reactor. It also contains data on the amounts and types of fuels to be loaded and relocated in the Production Reactor.

  18. Reactor outage schedule (tentative)

    Energy Technology Data Exchange (ETDEWEB)

    Walton, R.P.

    1969-10-15

    This single page document is the October 15, 1969 reactor refueling outage schedule for the Hanford Production Reactor. It also contains data on the amounts and types of fuels to be loaded and relocated in the Production Reactor.

  19. Reactor outage schedule (tentative)

    Energy Technology Data Exchange (ETDEWEB)

    Walton, R.P.

    1969-09-15

    This single page document is the September 15, 1969 reactor refueling outage schedule for the Hanford Production Reactor. It also contains data on the amounts and types of fuels to be loaded and relocated in the Production Reactor.

  20. Reactor outage schedule (tentative)

    Energy Technology Data Exchange (ETDEWEB)

    Walton, R.P.

    1969-12-15

    This single page document is the December 16, 1969 reactor refueling outage schedule for the Hanford Production Reactor. It also contains data on the amounts and types of fuels to be loaded and relocated in the Production reactor.

  1. Reactor outage schedule (tentative)

    Energy Technology Data Exchange (ETDEWEB)

    Walton, R.P.

    1969-12-01

    This single page document is the December 1, 1969 reactor refueling outage schedule for the Hanford Production Reactor. It also contains data on the amounts and types of fuels to be loaded and relocated in the Production reactor.

  2. Supply chain optimization in the newspaper industry: Integrated production allocation, scheduling and distribution

    OpenAIRE

    Furnes, Kaia Kristina; Ravlo, Espen Huse

    2014-01-01

    One of the defining characteristics of the newspaper industry is that the products are virtually worthless at the end of the day; nobody wants to pay for yesterday s news. In addition, strict delivery deadlines and no inventory lead to very short time frames for production and distribution. Consequently production and outbound distribution are intimately linked and should be coordinated in order to achieve the objective of on-time delivery performance at minimum total cost. The increase in on...

  3. Optimizing Water Use and Hydropower Production in Operational Reservoir System Scheduling with RiverWare

    Science.gov (United States)

    Magee, T. M.; Zagona, E. A.

    2017-12-01

    Practical operational optimization of multipurpose reservoir systems is challenging for several reasons. Each purpose has its own constraints which may conflict with those of other purposes. While hydropower generation typically provides the bulk of the revenue, it is also among the lowest priority purposes. Each river system has important details that are specific to the location such as hydrology, reservoir storage capacity, physical limitations, bottlenecks, and the continuing evolution of operational policy. In addition, reservoir operations models include discrete, nonlinear, and nonconvex physical processes and if-then operating policies. Typically, the forecast horizon for scheduling needs to be extended far into the future to avoid near term (e.g., a few hours or a day) scheduling decisions that result in undesirable future states; this makes the computational effort much larger than may be expected. Put together, these challenges lead to large and customized mathematical optimization problems which must be solved efficiently to be of practical use. In addition, the solution process must be robust in an operational setting. We discuss a unique modeling approach in RiverWare that meets these challenges in an operational setting. The approach combines a Preemptive Linear Goal Programming optimization model to handle prioritized policies complimented by preprocessing and postprocessing with Rulebased Simulation to improve the solution with regard to nonlinearities, discrete issues, and if-then logic. An interactive policy language with a graphical user interface allows modelers to customize both the optimization and simulation based on the unique aspects of the policy for their system while the routine physical aspect of operations are modeled automatically. The modeler is aided by a set of compiled predefined functions and functions shared by other modelers. We illustrate the success of the approach with examples from daily use at the Tennessee Valley

  4. A prediction model to forecast the cost impact from a break in the production schedule

    Science.gov (United States)

    Delionback, L. M.

    1977-01-01

    The losses which are experienced after a break or stoppage in sequence of a production cycle portends an extremely complex situation and involves numerous variables, some of uncertain quantity and quality. There are no discrete formulas to define the losses during a gap in production. The techniques which are employed are therefore related to a prediction or forecast of the losses that take place, based on the conditions which exist in the production environment. Such parameters as learning curve slope, number of predecessor units, and length of time the production sequence is halted are utilized in formulating a prediction model. The pertinent current publications related to this subject are few in number, but are reviewed to provide an understanding of the problem. Example problems are illustrated together with appropriate trend curves to show the approach. Solved problems are also given to show the application of the models to actual cases or production breaks in the real world.

  5. A software product line approach to enhance a meta-scheduler middleware

    International Nuclear Information System (INIS)

    Scheidt, Rafael F; Schmidt, Katreen; Pessoa, Gabriel M; Viera, Matheus A; Dantas, Mario

    2012-01-01

    Software Projects in general tend to get more software reuse and componentization in order to reduce time, cost and new products resources. The need for techniques and tools to organize projects of higher quality in less time is one of the greatest challenges of Software Engineering. The Software Product Line is proposed to organize and systematically assist the development of new products in series at the same domain. In this context, this paper is proposed to apply the Software Product Line approach in Distributed Computing Environments. In projects that involve Distributed Environments, each version of the same product can generate repeatedly the same artifacts in a product that evolves its characteristics; however there is a principal architecture with variations of components. The goal of the proposed approach is to analyze the actual process and propose a new approach to develop new projects reusing the whole architecture, components and documents, starting with a solid base and creating new products focusing in new functionalities. We expect that with the application of this approach give support to the development of projects in Distributed Computing Environment.

  6. Automated Scheduling Via Artificial Intelligence

    Science.gov (United States)

    Biefeld, Eric W.; Cooper, Lynne P.

    1991-01-01

    Artificial-intelligence software that automates scheduling developed in Operations Mission Planner (OMP) research project. Software used in both generation of new schedules and modification of existing schedules in view of changes in tasks and/or available resources. Approach based on iterative refinement. Although project focused upon scheduling of operations of scientific instruments and other equipment aboard spacecraft, also applicable to such terrestrial problems as scheduling production in factory.

  7. A simulation engine to support production scheduling using genetics-based machine learning

    OpenAIRE

    Tamaki, H.; Kryssanov, V. V.; Kitamura, S.

    2006-01-01

    The ever higher complexity of manufacturing systems, continually shortening life cycles of products and their increasing variety, as well as the unstable market situation of the recent years require introducing grater flexibility and responsiveness to manufacturing processes. From this perspective, one of the critical manufacturing tasks, which traditionally attract significant attention in both academia and the industry, but which have no satisfactory universal solution, is production schedu...

  8. 40 CFR Appendix H to Subpart A of... - Clean Air Act Amendments of 1990 Phaseout Schedule for Production of Ozone-Depleting Substances

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Clean Air Act Amendments of 1990 Phaseout Schedule for Production of Ozone-Depleting Substances H Appendix H to Subpart A of Part 82... STRATOSPHERIC OZONE Production and Consumption Controls Pt. 82, Subpt. A, App. H Appendix H to Subpart A of Part...

  9. Changing patterns of working time in Germany - from shorter working hours to more flexible work schedules

    OpenAIRE

    Seifert, Hartmut

    2010-01-01

    La reducción del tiempo de trabajo promete sustanciales efectos sobre el empleo. La reducción del tiempo de trabajo, combinada con la flexibilización del tiempo de trabajo se ha mostrado como una buena experiencia porque permite reducir los costes laborales, mejorar la productividad y mantener el empleo. Los incentivos sobre las contribuciones sociales pueden contribuir no sólo a la mejora del empleo, sino también a reducir la carga del gasto público por desempleo. Sin embar...

  10. Freezing issue on stability master production scheduling for supplier network: Decision making view

    OpenAIRE

    Aisyati Azizah; Samadhi T.M.A. Ari; Ma’ruf Anas; Cakravastia Andi

    2017-01-01

    In the daily operation, there are frequently changes in customer order requirement which will induce instability of the MPS. Moreover, the frequently adjustment of MPS can induce fluctuation of production and increasing of inventory cost as well as decreasing service level of customer. Most of studies about instability of MPS use freezing method and rolling procedure to adjust MPS periodically. Freezing is the proportion of planning horizon being frozen, whereas rolling procedure is a method ...

  11. Using the method of ideal point to solve dual-objective problem for production scheduling

    Directory of Open Access Journals (Sweden)

    Mariia Marko

    2016-07-01

    Full Text Available In practice, there are often problems, which must simultaneously optimize several criterias. This so-called multi-objective optimization problem. In the article we consider the use of the method ideal point to solve the two-objective optimization problem of production planning. The process of finding solution to the problem consists of a series of steps where using simplex method, we find the ideal point. After that for solving a scalar problems, we use the method of Lagrange multipliers

  12. Groundwater availability study for Guam; goals, approach, products, and schedule of activities

    Science.gov (United States)

    Gingerich, Stephen B.; Jenson, John W.

    2010-01-01

    An expected significant population increase on Guam has raised concern about the sustainability of groundwater resources. In response, the U.S. Geological Survey (USGS), in collaboration with the University of Guam's Water and Environmental Research Institute of the Western Pacific (WERI) and with funding from the U.S. Marine Corps (USMC), is conducting a 3.5-year study to advance understanding of regional groundwater dynamics in the Northern Guam Lens Aquifer, provide a new estimate of groundwater recharge, and develop a numerical groundwater flow and transport model for northern Guam. Results of the study, including two USGS reports and a well database, will provide more reliable evaluations of the potential effects of groundwater production and help guide sustainable management of this critical resource.

  13. 36 CFR 223.81 - Shorter advertising periods in emergencies.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Shorter advertising periods... OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER Timber Sale Contracts Advertisement and Bids § 223.81 Shorter advertising periods in emergencies. In emergency situations where prompt...

  14. Schedule Analytics

    Science.gov (United States)

    2016-04-30

    Warfare, Naval Sea Systems Command Acquisition Cycle Time : Defining the Problem David Tate, Institute for Defense Analyses Schedule Analytics Jennifer...research was comprised of the following high- level steps :  Identify and review primary data sources 1...research. However, detailed reviews of the OMB IT Dashboard data revealed that schedule data is highly aggregated. Program start date and program end date

  15. The impact of service-specific staffing, case scheduling, turnovers, and first-case starts on anesthesia group and operating room productivity: a tutorial using data from an Australian hospital.

    Science.gov (United States)

    McIntosh, Catherine; Dexter, Franklin; Epstein, Richard H

    2006-12-01

    In this tutorial, we consider the impact of operating room (OR) management on anesthesia group and OR labor productivity and costs. Most of the tutorial focuses on the steps required for each facility to refine its OR allocations using its own data collected during patient care. Data from a hospital in Australia are used throughout to illustrate the methods. OR allocation is a two-stage process. During the initial tactical stage of allocating OR time, OR capacity ("block time") is adjusted. For operational decision-making on a shorter-term basis, the existing workload can be considered fixed. Staffing is matched to that workload based on maximizing the efficiency of use of OR time. Scheduling cases and making decisions on the day of surgery to increase OR efficiency are worthwhile interventions to increase anesthesia group productivity. However, by far, the most important step is the appropriate refinement of OR allocations (i.e., planning service-specific staffing) 2-3 mo before the day of surgery. Reducing surgical and/or turnover times and delays in first-case-of-the-day starts generally provides small reductions in OR labor costs. Results vary widely because they are highly sensitive both to the OR allocations (i.e., staffing) and to the appropriateness of those OR allocations.

  16. A Study on the Optimum Bucket Size for Master Scheduling : For the Case of Hierarchically tured Products

    OpenAIRE

    木内, 正光

    2010-01-01

    The function of master scheduling is to plan the flow of order from its arrival to its completion. In this study, the problem of bucket size for master scheduling is taken up. The bucket size for master scheduling has much influence on the lead time of the order. However, to date there is no clear method for how to set the optimum bucket size. The purpose of this study is to propose a method to set the optimum bucket size. In this paper, an equation to estimate the optimum bucket size is prop...

  17. The Napoleon Complex: When Shorter Men Take More.

    Science.gov (United States)

    Knapen, Jill E P; Blaker, Nancy M; Van Vugt, Mark

    2018-05-01

    Inspired by an evolutionary psychological perspective on the Napoleon complex, we hypothesized that shorter males are more likely to show indirect aggression in resource competitions with taller males. Three studies provide support for our interpretation of the Napoleon complex. Our pilot study shows that men (but not women) keep more resources for themselves when they feel small. When paired with a taller male opponent (Study 1), shorter men keep more resources to themselves in a game in which they have all the power (dictator game) versus a game in which the opponent also has some power (ultimatum game). Furthermore, shorter men are not more likely to show direct, physical aggression toward a taller opponent (Study 2). As predicted by the Napoleon complex, we conclude that (relatively) shorter men show greater behavioral flexibility in securing resources when presented with cues that they are physically less competitive. Theoretical and practical implications are discussed.

  18. College Students Understanding of Production Management and Master Production Schedule through Using a Real World Tool, Complimented with Company Tours and In- Class Visits, Provides an Excellent Learning Experience at Farmingdale State College

    Directory of Open Access Journals (Sweden)

    Jill Anne O'Sullivan

    2015-08-01

    Full Text Available Manufacturing is playing a significant role in its re-shoring into America. Companies are grappling with ways to obtain that competitive advantage by distinguishing themselves through their intellectual capabilities, process improvements, technology, people, shop floor management and information flows. The purpose of this paper is to describe the effort at Farmingdale State College to educate our students in understanding Production Management and Master Production Schedule (MPS. We are trying to prepare students for entry into the workforce. By using a Real world ERP tool in the classroom while complimenting this learning with touring local manufacturers who use this tool and having production control experts in our classrooms. [1] The opportunity presents itself for these students to visit real world manufacturers using the same tool these students use in the classroom, the Infor Visual ERP. Each semester students go to a local manufacturer to see how the product is made and the ERP system is used to make it. Each semester a subject matter expert, SME, in manufacturing comes into the class and talks about how they use their ERP to perform their functional responsibilities. Students go into these companies and sit down with these Production Manufacturing and IT SME's to see how they use the modules in their ERP system from estimating, Production Management, MPS to delivery and payment. From the manufacturing window to the Master Schedule Window students learn from these companies SME's just how they perform their functions, how they use this tool. Then that is replicated this in the classroom lab assignments for students to better understand Production Management, scheduling and work order integrity. They identify the desired schedule (forecast and populate a Master Production Schedule. They create a BOM with work orders adding operations and material. The Production Management/Control is the function of directing or regulating the movement of

  19. Erratum to ''Johnson's algorithm : A key to solve optimally or approximately flowshop scheduling problems with unavailability periods'' [International Journal of Production Economics 121 (2009) 81-87

    OpenAIRE

    Rapine , Christophe

    2013-01-01

    International audience; In Allaoui H., Artiba A, ''Johnson's algorithm : A key to solve optimally or approximately flowshop scheduling problems with unavailability periods'' [International Journal of Production Economics 121 (2009)] the authors propose optimality conditions for the Johnson sequence in presence of one unavailability period on the first machine and pretend for a performance guarantee of 2 when several unavailability periods may occur. We establish in this note that these condit...

  20. Erratum to "Scheduling of a two-machine flowshop with availability constraints on the first machine" [International Journal of Production Economics 99 (2006)

    OpenAIRE

    Rapine , Christophe

    2013-01-01

    International audience; In Allaoui H., Artiba A., Elmaghraby S.E., Riane F. Scheduling of a two-machine flowshop with availability constraints on the first machine. International Journal of Production Economics 99 (2006) two conditions of optimality for the Johnson sequence are given. We establish in this note that these conditions are false, under the resumable and the non-resumable case. We also point out two incorrect proofs and give evidence that the time complexity of their dynamic appro...

  1. Self-certification and employee training of mail-order distributors of scheduled listed chemical products. Interim final rule with request for comment.

    Science.gov (United States)

    2011-04-13

    On October 12, 2010, the President signed the Combat Methamphetamine Enhancement Act of 2010 (MEA). It establishes new requirements for mail-order distributors of scheduled listed chemical products. Mail-order distributors must now self-certify to DEA in order to sell scheduled listed chemical products at retail. Sales at retail are those sales intended for personal use; mail-order distributors that sell scheduled listed chemical products not intended for personal use, e.g., sale to a university, are not affected by the new law. This self-certification must include a statement that the mail-order distributor understands each of the requirements that apply under part 1314 and agrees to comply with these requirements. Additionally, mail-order distributors are now required to train their employees prior to self certification. DEA is promulgating this rule to incorporate the statutory provisions and make its regulations consistent with the new requirements and other existing regulations related to self-certification.

  2. ATLAS construction schedule

    CERN Multimedia

    Kotamaki, M

    The goal during the last few months has been to freeze and baseline as much as possible the schedules of various ATLAS systems and activities. The main motivations for the re-baselining of the schedules have been the new LHC schedule aiming at first collisions in early 2006 and the encountered delays in civil engineering as well as in the production of some of the detectors. The process was started by first preparing a new installation schedule that takes into account all the new external constraints and the new ATLAS staging scenario. The installation schedule version 3 was approved in the March EB and it provides the Ready For Installation (RFI) milestones for each system, i.e. the date when the system should be available for the start of the installation. TCn is now interacting with the systems aiming at a more realistic and resource loaded version 4 before the end of the year. Using the new RFI milestones as driving dates a new summary schedule has been prepared, or is under preparation, for each system....

  3. MO-E-BRD-02: Accelerated Partial Breast Irradiation in Brachytherapy: Is Shorter Better?

    International Nuclear Information System (INIS)

    Todor, D.

    2015-01-01

    Is Non-invasive Image-Guided Breast Brachytherapy Good? – Jess Hiatt, MS Non-invasive Image-Guided Breast Brachytherapy (NIBB) is an emerging therapy for breast boost treatments as well as Accelerated Partial Breast Irradiation (APBI) using HDR surface breast brachytherapy. NIBB allows for smaller treatment volumes while maintaining optimal target coverage. Considering the real-time image-guidance and immobilization provided by the NIBB modality, minimal margins around the target tissue are necessary. Accelerated Partial Breast Irradiation in brachytherapy: is shorter better? - Dorin Todor, PhD VCU A review of balloon and strut devices will be provided together with the origins of APBI: the interstitial multi-catheter implant. A dosimetric and radiobiological perspective will help point out the evolution in breast brachytherapy, both in terms of devices and the protocols/clinical trials under which these devices are used. Improvements in imaging, delivery modalities and convenience are among the factors driving the ultrashort fractionation schedules but our understanding of both local control and toxicities associated with various treatments is lagging. A comparison between various schedules, from a radiobiological perspective, will be given together with a critical analysis of the issues. to review and understand the evolution and development of APBI using brachytherapy methods to understand the basis and limitations of radio-biological ‘equivalence’ between fractionation schedules to review commonly used and proposed fractionation schedules Intra-operative breast brachytherapy: Is one stop shopping best?- Bruce Libby, PhD. University of Virginia A review of intraoperative breast brachytherapy will be presented, including the Targit-A and other trials that have used electronic brachytherapy. More modern approaches, in which the lumpectomy procedure is integrated into an APBI workflow, will also be discussed. Learning Objectives: To review past and current

  4. MO-E-BRD-02: Accelerated Partial Breast Irradiation in Brachytherapy: Is Shorter Better?

    Energy Technology Data Exchange (ETDEWEB)

    Todor, D. [Virginia Commonwealth University (United States)

    2015-06-15

    Is Non-invasive Image-Guided Breast Brachytherapy Good? – Jess Hiatt, MS Non-invasive Image-Guided Breast Brachytherapy (NIBB) is an emerging therapy for breast boost treatments as well as Accelerated Partial Breast Irradiation (APBI) using HDR surface breast brachytherapy. NIBB allows for smaller treatment volumes while maintaining optimal target coverage. Considering the real-time image-guidance and immobilization provided by the NIBB modality, minimal margins around the target tissue are necessary. Accelerated Partial Breast Irradiation in brachytherapy: is shorter better? - Dorin Todor, PhD VCU A review of balloon and strut devices will be provided together with the origins of APBI: the interstitial multi-catheter implant. A dosimetric and radiobiological perspective will help point out the evolution in breast brachytherapy, both in terms of devices and the protocols/clinical trials under which these devices are used. Improvements in imaging, delivery modalities and convenience are among the factors driving the ultrashort fractionation schedules but our understanding of both local control and toxicities associated with various treatments is lagging. A comparison between various schedules, from a radiobiological perspective, will be given together with a critical analysis of the issues. to review and understand the evolution and development of APBI using brachytherapy methods to understand the basis and limitations of radio-biological ‘equivalence’ between fractionation schedules to review commonly used and proposed fractionation schedules Intra-operative breast brachytherapy: Is one stop shopping best?- Bruce Libby, PhD. University of Virginia A review of intraoperative breast brachytherapy will be presented, including the Targit-A and other trials that have used electronic brachytherapy. More modern approaches, in which the lumpectomy procedure is integrated into an APBI workflow, will also be discussed. Learning Objectives: To review past and current

  5. 2007 Wholesale Power Rate Schedules : 2007 General Rate Schedule Provisions.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    2006-11-01

    This schedule is available for the contract purchase of Firm Power to be used within the Pacific Northwest (PNW). Priority Firm (PF) Power may be purchased by public bodies, cooperatives, and Federal agencies for resale to ultimate consumers, for direct consumption, and for Construction, Test and Start-Up, and Station Service. Rates in this schedule are in effect beginning October 1, 2006, and apply to purchases under requirements Firm Power sales contracts for a three-year period. The Slice Product is only available for public bodies and cooperatives who have signed Slice contracts for the FY 2002-2011 period. Utilities participating in the Residential Exchange Program (REP) under Section 5(c) of the Northwest Power Act may purchase Priority Firm Power pursuant to the Residential Exchange Program. Rates under contracts that contain charges that escalate based on BPA's Priority Firm Power rates shall be based on the three-year rates listed in this rate schedule in addition to applicable transmission charges. This rate schedule supersedes the PF-02 rate schedule, which went into effect October 1, 2001. Sales under the PF-07 rate schedule are subject to BPA's 2007 General Rate Schedule Provisions (2007 GRSPs). Products available under this rate schedule are defined in the 2007 GRSPs. For sales under this rate schedule, bills shall be rendered and payments due pursuant to BPA's 2007 GRSPs and billing process.

  6. Effects of deficit drip-irrigation scheduling regimes with saline water on pepper yield, water productivity and soil salinity under arid conditions of Tunisia

    Directory of Open Access Journals (Sweden)

    Kamel Nagaz

    2012-12-01

    Full Text Available A two-year study was carried out in order to assess the effects of different irrigation scheduling regimes with saline water on soil salinity, yield and water productivity of pepper under actual commercial-farming conditions in the arid region of Tunisia. Pepper was grown on a sandy soil and drip-irrigated with water having an ECi of 3.6 dS/m. Irrigation treatments consisted in water replacements of accumulated ETc at levels of 100% (FI, full irrigation, 80% (DI-80, 60% (DI-60, when the readily available water in the control treatment (FI is depleted, deficit irrigation during ripening stage (FI-MDI60 and farmer method corresponding to irrigation practices implemented by the local farmers (FM. Results on pepper yield and soil salinity are globally consistent between the two-year experiments and shows significant difference between irrigation regimes. Higher soil salinity was maintained over the two seasons, 2008 and 2009, with DI-60 and FM treatments than FI. FI-MDI60 and DI-80 treatments resulted also in low ECe values. Highest yields for both years were obtained under FI (22.3 and 24.4 t/ha although we didn’t find significant differences with the regulated deficit irrigation treatment (FI-DI60. However, the DI-80 and DI-60 treatments caused significant reductions in pepper yields through a reduction in fruits number/m² and average fruit weight in comparison with FI treatment. The FM increased soil salinity and caused significant reductions in yield with 14 to 43%, 12 to 39% more irrigation water use than FI, FI-MDI60 and DI-80 treatments, respectively, in 2008 and 2009. Yields for all irrigation treatments were higher in the second year compared to the first year. Water productivity (WP values reflected this difference and varied between 2.31 and 5.49 kg/m3. The WP was found to vary significantly among treatments, where the highest and the lowest values were observed for DI-60 treatment and FM, respectively. FI treatment provides

  7. Effects of Blocked and Random Practice Schedule on Outcomes of Sound Production Treatment for Acquired Apraxia of Speech: Results of a Group Investigation.

    Science.gov (United States)

    Wambaugh, Julie L; Nessler, Christina; Wright, Sandra; Mauszycki, Shannon C; DeLong, Catharine; Berggren, Kiera; Bailey, Dallin J

    2017-06-22

    The purpose of this investigation was to compare the effects of schedule of practice (i.e., blocked vs. random) on outcomes of Sound Production Treatment (SPT; Wambaugh, Kalinyak-Fliszar, West, & Doyle, 1998) for speakers with chronic acquired apraxia of speech and aphasia. A combination of group and single-case experimental designs was used. Twenty participants each received SPT administered with randomized stimuli presentation (SPT-R) and SPT applied with blocked stimuli presentation (SPT-B). Treatment effects were examined with respect to accuracy of articulation as measured in treated and untreated experimental words produced during probes. All participants demonstrated improved articulation of treated items with both practice schedules. Effect sizes were calculated to estimate magnitude of change for treated and untreated items by treatment condition. No significant differences were found for SPT-R and SPT-B relative to effect size. Percent change over the highest baseline performance was also calculated to provide a clinically relevant indication of improvement. Change scores associated with SPT-R were significantly higher than those for SPT-B for treated items but not untreated items. SPT can result in improved articulation regardless of schedule of practice. However, SPT-R may result in greater gains for treated items. https://doi.org/10.23641/asha.5116831.

  8. SPANR planning and scheduling

    Science.gov (United States)

    Freund, Richard F.; Braun, Tracy D.; Kussow, Matthew; Godfrey, Michael; Koyama, Terry

    2001-07-01

    SPANR (Schedule, Plan, Assess Networked Resources) is (i) a pre-run, off-line planning and (ii) a runtime, just-in-time scheduling mechanism. It is designed to support primarily commercial applications in that it optimizes throughput rather than individual jobs (unless they have highest priority). Thus it is a tool for a commercial production manager to maximize total work. First the SPANR Planner is presented showing the ability to do predictive 'what-if' planning. It can answer such questions as, (i) what is the overall effect of acquiring new hardware or (ii) what would be the effect of a different scheduler. The ability of the SPANR Planner to formulate in advance tree-trimming strategies is useful in several commercial applications, such as electronic design or pharmaceutical simulations. The SPANR Planner is demonstrated using a variety of benchmarks. The SPANR Runtime Scheduler (RS) is briefly presented. The SPANR RS can provide benefit for several commercial applications, such as airframe design and financial applications. Finally a design is shown whereby SPANR can provide scheduling advice to most resource management systems.

  9. Heliostat-field gain-scheduling control applied to a two-step solar hydrogen production plant

    International Nuclear Information System (INIS)

    Roca, Lidia; Calle, Alberto de la; Yebra, Luis J.

    2013-01-01

    Highlights: ► A control system is proposed for a solar reactor system which produces hydrogen. ► The controller chooses which heliostats from the solar field must be focused. ► A gain scheduling scheme is included to deal with different system dynamics. ► The scheme is tested and tunned in simulation. ► Real experiments show the promising results of this work. -- Abstract: This article describes a temperature control structure designed for the interior of a solar hydrogen reactor based on a two-step ferrite-redox technology. Until now, this temperature has been controlled by manual selection of the heliostats to be focused on the receiver targets. However, the strong system dependency on operating conditions suggests that the procedure be automated in order to ensure the desired setpoint change response. The aims are to maintain the desired temperatures and to make the setpoint switch as fast as possible, keeping plant conditions within the margins of safety. The scheme proposed includes a procedure for selecting the heliostats to be focused on the reactor by using a simple model of the solar field and a gain scheduling control system which changes the control tuning parameters to deal with the varying dynamics observed during the process. Real experiments show the promising results of this work.

  10. Mixed-Integer Linear Programming approaches to shelf-life-integrated planning and scheduling in yoghurt production

    NARCIS (Netherlands)

    Lütke Entrup, M.; Günther, H.O.; Beek, van P.; Grunow, M.; Seiler, T.

    2005-01-01

    In the production of perishable products such as dairy, meat or bakery goods, the consideration of shelf life in production planning is of particular importance. Retail customers with relatively low inventory turns can benefit significantly from longer product shelf life as wastage and out-of-stock

  11. One long chain among shorter chains : the Flory approach revisited

    OpenAIRE

    Raphaël , E.; Fredrickson , G.; Pincus , P.

    1992-01-01

    We consider the mean square end-to-end distance of a long chain immersed in a monodisperse, concentrated solution of shorter, chemically identical chains. In contrast with the earlier work of Flory, no simplifying assumption on the wave vector dependence of the effective potential between segments is made. In order to obtain a closed form expression for the dimension of the long chain, we first derive a general expression for the mean square end-to-end distance of a flexible chain with arbitr...

  12. Integrated Harvest and Distribution Scheduling with Time Windows of Perishable Agri-Products in One-Belt and One-Road Context

    Directory of Open Access Journals (Sweden)

    Yiping Jiang

    2018-05-01

    Full Text Available The unique characteristics of perishable agri-products are a short lifespan and rapid quality deterioration. This establishes the need to significantly reduce the time from harvest to distribution. These features require reducing the processing time from harvest to distribution to being as short as possible. In this study, we focus on an integrated perishable agri-products scheduling problem that combines harvest and distribution simultaneously, with the purpose of reducing processing time and quality decay. We propose this problem as a mixed integer nonlinear programming model (MINLP to optimize the harvest time and the vehicle routing to consumers, and this MINIP is formulated as a vehicle routing problem with time windows (VRPTW. We introduce a big M method to transform the nonlinear model into a linear model, then apply CPLEX to solve the transformed model. Numerical experiments and sensitive analysis are conducted to verify the efficiency of the proposed model and to provide managerial insights.

  13. Do shorter wavelengths improve contrast in optical mammography?

    International Nuclear Information System (INIS)

    Taroni, P; Pifferi, A; Torricelli, A; Spinelli, L; Danesini, G M; Cubeddu, R

    2004-01-01

    The detection of tumours with time-resolved transmittance imaging relies essentially on blood absorption. Previous theoretical and phantom studies have shown that both contrast and spatial resolution of optical images are affected by the optical properties of the background medium, and high absorption and scattering are generally beneficial. Based on these observations, wavelengths shorter than presently used (680-780 nm) could be profitable for optical mammography. A study was thus performed analysing time-resolved transmittance images at 637, 656, 683 and 785 nm obtained from 26 patients bearing 16 tumours and 15 cysts. The optical contrast proved to increase upon decreasing wavelengths for the detection of cancers in late-gated intensity images, with higher gain in contrast for lesions of smaller size (<1.5 cm diameter). For cysts either a progressive increase or decrease in contrast with wavelength was observed in scattering images

  14. The risk of shorter fasting time for pediatric deep sedation.

    Science.gov (United States)

    Clark, Mathew; Birisci, Esma; Anderson, Jordan E; Anliker, Christina M; Bryant, Micheal A; Downs, Craig; Dalabih, Abdallah

    2016-01-01

    Current guidelines adopted by the American Academy of Pediatrics calls for prolonged fasting times before performing pediatric procedural sedation and analgesia (PSA). PSA is increasingly provided to children outside of the operating theater by sedation trained pediatric providers and does not require airway manipulation. We investigated the safety of a shorter fasting time compared to a longer and guideline compliant fasting time. We tried to identify the association between fasting time and sedation-related complications. This is a prospective observational study that included children 2 months to 18 years of age and had an American Society of Anesthesiologists physical status classification of I or II, who underwent deep sedation for elective procedures, performed by pediatric critical care providers. Procedures included radiologic imaging studies, electroencephalograms, auditory brainstem response, echocardiograms, Botox injections, and other minor surgical procedures. Subjects were divided into two groups depending on the length of their fasting time (4-6 h and >6 h). Complication rates were calculated and compared between the three groups. In the studied group of 2487 subjects, 1007 (40.5%) had fasting time of 4-6 h and the remaining 1480 (59.5%) subjects had fasted for >6 h. There were no statistically significant differences in any of the studied complications between the two groups. This study found no difference in complication rate in regard to the fasting time among our subjects cohort, which included only healthy children receiving elective procedures performed by sedation trained pediatric critical care providers. This suggests that using shorter fasting time may be safe for procedures performed outside of the operating theater that does not involve high-risk patients or airway manipulation.

  15. Mathematical models for a batch scheduling problem to minimize earliness and tardiness

    Directory of Open Access Journals (Sweden)

    Basar Ogun

    2018-05-01

    Full Text Available Purpose: Today’s manufacturing facilities are challenged by highly customized products and just in time manufacturing and delivery of these products. In this study, a batch scheduling problem is addressed to provide on-time completion of customer orders in the environment of lean manufacturing. The problem is to optimize partitioning of product components into batches and scheduling of the resulting batches where each customer order is received as a set of products made of various components. Design/methodology/approach: Three different mathematical models for minimization of total earliness and tardiness of customer orders are developed to provide on-time completion of customer orders and also, to avoid from inventory of final products. The first model is a non-linear integer programming model while the second is a linearized version of the first. Finally, to solve larger sized instances of the problem, an alternative linear integer model is presented. Findings: Computational study using a suit set of test instances showed that the alternative linear integer model is able to solve all test instances in varying sizes within quite shorter computer times comparing to the other two models. It was also showed that the alternative model can solve moderate sized real-world problems. Originality/value: The problem under study differentiates from existing batch scheduling problems in the literature since it includes new circumstances which may arise in real-world applications. This research, also, contributes the literature of batch scheduling problem by presenting new optimization models.

  16. Influence of the revision of surgical fee schedule on surgeons' productivity in Japan: A cohort analysis of 7602 surgical procedures in 2013-2016.

    Science.gov (United States)

    Nakata, Yoshinori; Watanabe, Yuichi; Narimatsu, Hiroto; Yoshimura, Tatsuya; Otake, Hiroshi; Sawa, Tomohiro

    2018-02-01

    The goal of this study is to evaluate the pure impact of the revision of surgical fee schedule on surgeons' productivity. We collected data from the surgical procedures performed by the surgeons working in Teikyo University Hospital from 1 April through 30 September in 2013-2016. We employed non-radial and non-oriented Malmquist model. We defined the decision-making unit as a surgeon with the highest academic rank in surgery. Inputs were defined as (1) the number of doctors who assisted surgery and (2) the time of surgical operation. The output was defined as the surgical fee for each surgery. We focused on the revisions in 2014 and 2016. We first calculated each surgeon's natural logarithms of the changes in productivity, technique and efficiency in 2013-2014, in 2014-2015 and in 2015-2016. Then, we subtracted the changes in 2014-2015 from the changes in 2013-2014 and in 2015-2016. We analyzed 62 surgeons who performed 7602 surgical procedures. The productivity changes were not significantly different from 0. Their efficiency change was significantly greater than 0, while their technical change was smaller than 0 in revision 2014. Their efficiency change was significantly smaller than 0, while their technical change was greater than 0 in revision 2016 (p increase overall productivity through revision if we could increase both efficiency and technique.

  17. Proposing New Heuristic Approaches for Preventive Maintenance Scheduling

    Directory of Open Access Journals (Sweden)

    majid Esmailian

    2013-08-01

    Full Text Available The purpose of preventive maintenance management is to perform a series of tasks that prevent or minimize production breakdowns and improve reliability of production facilities. An important objective of preventive maintenance management is to minimize downtime of production facilities. In order to accomplish this objective, personnel should efficiently allocate resources and determine an effective maintenance schedule. Gopalakrishnan (1997 developed a mathematical model and four heuristic approaches to solve the preventive maintenance scheduling problem of assigning skilled personnel to work with tasks that require a set of corresponding skills. However, there are several limitations in the prior work in this area of research. The craft combination problem has not been solved because the craft combination is assumed as given. The craft combination problem concerns the computation of all combinations of assigning multi skilled workers to accomplishment of a particular task. In fact, determining craft combinations is difficult because of the exponential number of craft combinations that are possible. This research provides a heuristic approach for determining the craft combination and four new heuristic approach solution for the preventive maintenance scheduling problem with multi skilled workforce constraints. In order to examine the new heuristic approach and to compare the new heuristic approach with heuristic approach of Gopalakrishnan (1997, 81 standard problems have been generated based on the criterion suggested by from Gopalakrishnan (1997. The average solution quality (SQ of the new heuristic approaches is 1.86% and in old heuristic approaches is 8.32%. The solution time of new heuristic approaches are shorter than old heuristic approaches. The solution time of new heuristic approaches is 0.78 second and old heuristic approaches is 6.43 second, but the solution time of mathematical model provided by Gopalakrishnan (1997 is 152 second.

  18. 40 CFR Appendix D to Subpart A of... - Harmonized Tariff Schedule Description of Products That May Contain Controlled Substances in...

    Science.gov (United States)

    2010-07-01

    ... Dehumidifiers (other than those under 8415 or 8424 classified as “machines and mechanical appliances having... motors), coatings or cleaning fluids for aircraft maintenance, mold release agents (e.g. for production... oils or their fractions of heading No. 15.16. 2106.90 Food preparations not elsewhere specified or...

  19. 21 CFR 113.83 - Establishing scheduled processes.

    Science.gov (United States)

    2010-04-01

    ... commercial production runs should be determined on the basis of recognized scientific methods to be of a size... CONTAINERS Production and Process Controls § 113.83 Establishing scheduled processes. Scheduled processes for... production shall be adequately provided for in establishing the scheduled process. Critical factors, e.g...

  20. A Metaheuristic Scheduler for Time Division Multiplexed Network-on-Chip

    DEFF Research Database (Denmark)

    Sørensen, Rasmus Bo; Sparsø, Jens; Pedersen, Mark Ruvald

    2014-01-01

    significant practical implications, is the minimization of the TDM schedule period by over-provisioning bandwidth to connections with the smallest bandwidth requirements. Our results show that this is possible with only negligible impact on the schedule period. We evaluate the scheduler with seven different...... applications from the MCSL NOC benchmark suite. In the special case of all-to-all communication with equal bandwidths on all communication channels, we obtain schedules with a shorter period than reported in previous work....

  1. Comparison of the effect of accelerated and classic vaccination schedules against Hepatitis B on the short-term production of protective antibody level: a meta-analysis study

    Directory of Open Access Journals (Sweden)

    Siavash Vaziri

    2014-05-01

    Full Text Available Background: Hepatitis B is a common viral disease and one of the most common causes of cirrhosis and Hepatocellular Carcinoma (HCC. This disease is preventable via vaccination in most individuals. The aim of this study was to compare the accelerated and classic vaccination schedules against hepatitis B in the short-term production of protective antibody level. Methods: A couple of scientific internet resources were searched to find the relevant studies. The abstracts of 156 studies and full texts of some of them were reviewed and finally, 19 articles relevant to the objective of the study were selected. From among the 19 articles remained, 11 articles with a score of 3 out of 5 (JADAD SCORE were included as high quality studies. Results: The antibody level of 10 mIU/ml or above was considered as positive vaccination response. According to the results of random effect model, no statistically significant difference was reported between the accelerated and conventional vaccination methods in terms of serum protection (OR=0653, CI: 0.425-1.004. However, it seems that the accelerated method is less strong. Conclusion: Although it seems accelerated vaccination method has less power, the difference has been trivial in most of the studies. Accelerated vaccination is recommended in situations where faster protective antibody level is needed.

  2. Medical necessity for shorter lived radionuclides, specifically pure Iodine-123

    International Nuclear Information System (INIS)

    DeNardo, G.L.; DeNardo, S.J.; Hines, H.H.; Lagunas-Solar, M.C.; Jungerman, J.A.

    1985-01-01

    Iodine-123 has physical and radiochemical characteristics ideal for most tracer procedures performed in patients. Its use is generally preferable to the use of 131 I for diagnosis. The potential for 123 I can be realized only if a radiopharmaceutical of lesser radionuclide contamination is generally and economically available. Iodine-123 produced by direct methods has significant disadvantages relative to quality of procedure and radiation dosimetry. Our experience with 123 I(p,5n) during the past 12 years causes us to vigorously encourage general availability of an 123 I radiopharmaceutical of this quality. Using this product, the authors have prepared radiopharmaceuticals for use in the study of cancer, coagulation, and renal and thyroid diseases

  3. Interfaz entre el plan de producción y el programa de producción en ambientes de ensamble Interface between the production plan and the master production schedule in assembly environments

    Directory of Open Access Journals (Sweden)

    Marcos Moya Navarro

    2012-11-01

    Full Text Available En un entorno de producción existe una relación directa entre el mercado y los procesos de manufactura de los bienes. Sin embargo, cuando la producción está inmersa en un ambiente de ensamble, el procedimiento de la planificación y la programación se vuelve complejo, con el riesgo de que la empresa pierda ventaja competitiva en términos de incumplimiento de las fechas de entrega y elevados costos de planificación y control. La programación lineal constituye una herramienta apropiada para construir modelos de programación y control de la producción en entornos de manufactura complejos. El objetivo de este trabajo es mostrar la interfaz entre el plan de producción y el programa de producción en ambientes de ensamble mediante el modelado por programación lineal. Para ello, se seleccionó un entorno que produce tres productos finales cuya estructura de producto está dispuesta en tres niveles con un máximo de ocho componentes. Los datos proporcionados por el plan de producción se desglosaron en diez órdenes, cada una indicando el tipo de producto, la cantidad por producir y su respectiva fecha de entrega. Los resultados obtenidos en el programa de producción establecieron la recepción de pedidos planificados y el programa de componentes totales requeridos en cada periodo de producción, para minimizar los costos totales de emisión de órdenes de producción e inventario.In a production environment there is a direct relationship between the market and the manufacturing process of goods.When production is immersed in an assembly environment, the process of production planning and scheduling becomes complex, and the enterprises have the risk of losing competitive advantages in terms of not meeting delivery dates and production high costs. Linear programming has become an appropriate tool for production planning and scheduling in complex manufacturing environments. The aim of this paper is to show the interface between both the

  4. Online Scheduling in Manufacturing A Cumulative Delay Approach

    CERN Document Server

    Suwa, Haruhiko

    2013-01-01

    Online scheduling is recognized as the crucial decision-making process of production control at a phase of “being in production" according to the released shop floor schedule. Online scheduling can be also considered as one of key enablers to realize prompt capable-to-promise as well as available-to-promise to customers along with reducing production lead times under recent globalized competitive markets. Online Scheduling in Manufacturing introduces new approaches to online scheduling based on a concept of cumulative delay. The cumulative delay is regarded as consolidated information of uncertainties under a dynamic environment in manufacturing and can be collected constantly without much effort at any points in time during a schedule execution. In this approach, the cumulative delay of the schedule has the important role of a criterion for making a decision whether or not a schedule revision is carried out. The cumulative delay approach to trigger schedule revisions has the following capabilities for the ...

  5. Immunization Schedules for Adults

    Science.gov (United States)

    ... ACIP Vaccination Recommendations Why Immunize? Vaccines: The Basics Immunization Schedule for Adults (19 Years of Age and ... diseases that can be prevented by vaccines . 2018 Immunization Schedule Recommended Vaccinations for Adults by Age and ...

  6. Instant Childhood Immunization Schedule

    Science.gov (United States)

    ... Recommendations Why Immunize? Vaccines: The Basics Instant Childhood Immunization Schedule Recommend on Facebook Tweet Share Compartir Get ... date. See Disclaimer for additional details. Based on Immunization Schedule for Children 0 through 6 Years of ...

  7. Project scheduling method with time using MRP system – A case study: Construction project in Libya

    Directory of Open Access Journals (Sweden)

    Abdallah Ali Imetieg

    2015-04-01

    Full Text Available Materials Requirements and Planning (MRP is a system of production planning and inventory control, which is used to manage manufacturing processes. Most MRP systems are software-based and are used to ensure that the materials are available for production, that the products are available for delivery to customers, that the lowest possible material and product level is maintained in store, as well as to plan delivery schedules and purchasing activities. Upon completion of scheduling, begins the process of follow-up, which includes the achievement of the project goals in terms of quantity, quality and costs in accordance with deadlines. MRP system was applied to project of 5000 housing units in Solug area, which is close to Benghazi city, Libya, with the aim to provide necessary cash flow to pay dues on time without delay to all involved project sub-contractors and material suppliers, to ensure the smooth flow of operations, as well as to diminish costs by reduction of temporary storages and rented areas. There is a correlation between time and cost of each activity. If the required time is shorter than the scheduled time of the certain activity, it would demand more resources, which further leads to the increase in direct costs of the given activity. Therefore, the output of MRP is important since commands are issued through planning in order to launch the suggested orders with the required quantities and within the limited time period.

  8. Chronologically scheduled snacking with high-protein products within the habitual diet in type-2 diabetes patients leads to a fat mass loss: a longitudinal study

    Directory of Open Access Journals (Sweden)

    Martínez J Alfredo

    2011-07-01

    Full Text Available Abstract Background Obesity is the most relevant overnutrition disease worldwide and is associated to different metabolic disorders such as insulin resistance and type-2 diabetes. Low glycemic load foods and diets and moderately high protein intake have been shown to reduce body weight and fat mass, exerting also beneficial effects on LDL-cholesterol, triglyceride concentrations, postprandial glucose curve and HDL-cholesterol levels. The present study aimed at studying the potential functionality of a series of low glycemic index products with moderately high protein content, as possible coadjuvants in the control of type-2 diabetes and weight management following a chronologically planned snacking offer (morning and afternoon. Methods The current trial followed a single group, sequential, longitudinal design, with two consecutive periods of 4 weeks each. A total of 17 volunteers participated in the study. The first period was a free living period, with volunteers' habitual ad libitum dietary pattern, while the second period was a free-living period with structured meal replacements at breakfast, morning snack and afternoon snack, which were exchanged by specific products with moderately high protein content and controlled low glycemic index, following a scheduled temporal consumption. Blood extractions were performed at the beginning and at the end of each period (free-living and intervention. Parameters analysed were: fasting glucose, insulin, glycosylated hemoglobin, total-, HDL- and LDL-cholesterol, triglyceride, C - reactive protein and Homocysteine concentrations. Postprandial glucose and insulin were also measured. Anthropometrical parameters were monitored each 2 weeks during the whole study. Results A modest but significant (p = 0.002 reduction on body weight (1 kg was observed during the intervention period, mainly due to the fat mass loss (0.8 kg, p = 0.02. This weight reduction was observed without apparently associated changes in

  9. Web Publishing Schedule

    Science.gov (United States)

    Section 207(f)(2) of the E-Gov Act requires federal agencies to develop an inventory and establish a schedule of information to be published on their Web sites, make those schedules available for public comment. To post the schedules on the web site.

  10. Preemptive scheduling with rejection

    NARCIS (Netherlands)

    Hoogeveen, H.; Skutella, M.; Woeginger, Gerhard

    2003-01-01

    We consider the problem of preemptively scheduling a set of n jobs on m (identical, uniformly related, or unrelated) parallel machines. The scheduler may reject a subset of the jobs and thereby incur job-dependent penalties for each rejected job, and he must construct a schedule for the remaining

  11. Preemptive scheduling with rejection

    NARCIS (Netherlands)

    Hoogeveen, J.A.; Skutella, M.; Woeginger, G.J.; Paterson, M.

    2000-01-01

    We consider the problem of preemptively scheduling a set of n jobs on m (identical, uniformly related, or unrelated) parallel machines. The scheduler may reject a subset of the jobs and thereby incur job-dependent penalties for each rejected job, and he must construct a schedule for the remaining

  12. Outage scheduling and implementation

    International Nuclear Information System (INIS)

    Allison, J.E.; Segall, P.; Smith, R.R.

    1986-01-01

    Successful preparation and implementation of an outage schedule and completion of scheduled and emergent work within an identified critical path time frame is a result of careful coordination by Operations, Work Control, Maintenance, Engineering, Planning and Administration and others. At the Fast Flux Test Facility (FFTF) careful planning has been responsible for meeting all scheduled outage critical paths

  13. Scheduling with Time Lags

    NARCIS (Netherlands)

    X. Zhang (Xiandong)

    2010-01-01

    textabstractScheduling is essential when activities need to be allocated to scarce resources over time. Motivated by the problem of scheduling barges along container terminals in the Port of Rotterdam, this thesis designs and analyzes algorithms for various on-line and off-line scheduling problems

  14. NASA scheduling technologies

    Science.gov (United States)

    Adair, Jerry R.

    1994-01-01

    This paper is a consolidated report on ten major planning and scheduling systems that have been developed by the National Aeronautics and Space Administration (NASA). A description of each system, its components, and how it could be potentially used in private industry is provided in this paper. The planning and scheduling technology represented by the systems ranges from activity based scheduling employing artificial intelligence (AI) techniques to constraint based, iterative repair scheduling. The space related application domains in which the systems have been deployed vary from Space Shuttle monitoring during launch countdown to long term Hubble Space Telescope (HST) scheduling. This paper also describes any correlation that may exist between the work done on different planning and scheduling systems. Finally, this paper documents the lessons learned from the work and research performed in planning and scheduling technology and describes the areas where future work will be conducted.

  15. A shorter and more specific oral sensitization-based experimental model of food allergy in mice.

    Science.gov (United States)

    Bailón, Elvira; Cueto-Sola, Margarita; Utrilla, Pilar; Rodríguez-Ruiz, Judith; Garrido-Mesa, Natividad; Zarzuelo, Antonio; Xaus, Jordi; Gálvez, Julio; Comalada, Mònica

    2012-07-31

    Cow's milk protein allergy (CMPA) is one of the most prevalent human food-borne allergies, particularly in children. Experimental animal models have become critical tools with which to perform research on new therapeutic approaches and on the molecular mechanisms involved. However, oral food allergen sensitization in mice requires several weeks and is usually associated with unspecific immune responses. To overcome these inconveniences, we have developed a new food allergy model that takes only two weeks while retaining the main characters of allergic response to food antigens. The new model is characterized by oral sensitization of weaned Balb/c mice with 5 doses of purified cow's milk protein (CMP) plus cholera toxin (CT) for only two weeks and posterior challenge with an intraperitoneal administration of the allergen at the end of the sensitization period. In parallel, we studied a conventional protocol that lasts for seven weeks, and also the non-specific effects exerted by CT in both protocols. The shorter protocol achieves a similar clinical score as the original food allergy model without macroscopically affecting gut morphology or physiology. Moreover, the shorter protocol caused an increased IL-4 production and a more selective antigen-specific IgG1 response. Finally, the extended CT administration during the sensitization period of the conventional protocol is responsible for the exacerbated immune response observed in that model. Therefore, the new model presented here allows a reduction not only in experimental time but also in the number of animals required per experiment while maintaining the features of conventional allergy models. We propose that the new protocol reported will contribute to advancing allergy research. Copyright © 2012 Elsevier B.V. All rights reserved.

  16. Scheduling optimization of a real-world multi product pipeline network; Otimizacao das operacoes de transporte de derivados de petroleo em redes de dutos

    Energy Technology Data Exchange (ETDEWEB)

    Boschetto, Suelen N.; Felizari, Luiz C.; Magatao, Leandro; Stebel, Sergio L.; Neves Junior, Flavio; Lueders, Ricardo; Arruda, Lucia V.R. de [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil); Ribas, Paulo Cesar; Bernardo, Luiz F.J. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES)

    2008-07-01

    This work develops an optimization structure to aid the operational decision-making of scheduling activities in a real world pipeline network. The proposed approach is based on a decomposition method to address complex problems with high computational burden. The Pre-analysis makes a previous evaluation of a batch sequencing, getting information to be entered into optimization block. The continuous time Mixed Integer Linear Program (MILP) model gets such information and calculates the scheduling. The models are applied to a pipeline network that connects different areas including refineries, terminals, and final clients. Many oil derivatives (e.g. gasoline, liquefied petroleum gas, naphtha) can be sent or received in this network. The computational burden to determine a short-term scheduling within the considered scenario is a relevant issue. Many insights have been derived from the obtained solutions, which are given in a reduced computational time for oil industrial-size scenarios. (author)

  17. Working Less and Enjoying It More: Alternative Work Schedules.

    Science.gov (United States)

    Shanks, Katherine

    1984-01-01

    Explores three forms of alternative work schedules that research has shown improve job performance and decrease absenteeism: flextime (starting and stopping times vary within limits); permanent part-time employment (regular employment carried out during shorter working hours); and job sharing (two or more part-time employees share one full-time…

  18. Analyzing scheduling in the food-processing industry

    DEFF Research Database (Denmark)

    Akkerman, Renzo; van Donk, Dirk Pieter

    2009-01-01

    Production scheduling has been widely studied in several research areas, resulting in a large number of methods, prescriptions, and approaches. However, the impact on scheduling practice seems relatively low. This is also the case in the food-processing industry, where industry......-specific characteristics induce specific and complex scheduling problems. Based on ideas about decomposition of the scheduling task and the production process, we develop an analysis methodology for scheduling problems in food processing. This combines an analysis of structural (technological) elements of the production...... process with an analysis of the tasks of the scheduler. This helps to understand, describe, and structure scheduling problems in food processing, and forms a basis for improving scheduling and applying methods developed in literature. It also helps in evaluating the organisational structures...

  19. Alternative Work Schedules Increase Employee Satisfaction.

    Science.gov (United States)

    Turney, John R.; Cohen, Stanley L.

    1983-01-01

    Facets of alternative work schedules (AWS) are discussed: importance of employee control, possible negative consequences, AWS handbook, time monitoring systems, and treatment of exceptions. AWS' effect on productivity and motivation is examined. (SK)

  20. Scheduling for decommissioning projects

    International Nuclear Information System (INIS)

    Podmajersky, O.E.

    1987-01-01

    This paper describes the Project Scheduling system being employed by the Decommissioning Operations Contractor at the Shippingport Station Decommissioning Project (SSDP). Results from the planning system show that the project continues to achieve its cost and schedule goals. An integrated cost and schedule control system (C/SCS) which uses the concept of earned value for measurement of performance was instituted in accordance with DOE orders. The schedule and cost variances generated by the C/SCS system are used to confirm management's assessment of project status. This paper describes the types of schedules and tools used on the SSDP project to plan and monitor the work, and identifies factors that are unique to a decommissioning project that make scheduling critical to the achievement of the project's goals. 1 fig

  1. Program reference schedule baseline

    International Nuclear Information System (INIS)

    1986-07-01

    This Program Reference Schedule Baseline (PRSB) provides the baseline Program-level milestones and associated schedules for the Civilian Radioactive Waste Management Program. It integrates all Program-level schedule-related activities. This schedule baseline will be used by the Director, Office of Civilian Radioactive Waste Management (OCRWM), and his staff to monitor compliance with Program objectives. Chapter 1 includes brief discussions concerning the relationship of the PRSB to the Program Reference Cost Baseline (PRCB), the Mission Plan, the Project Decision Schedule, the Total System Life Cycle Cost report, the Program Management Information System report, the Program Milestone Review, annual budget preparation, and system element plans. Chapter 2 includes the identification of all Level 0, or Program-level, milestones, while Chapter 3 presents and discusses the critical path schedules that correspond to those Level 0 milestones

  2. Approximating Preemptive Stochastic Scheduling

    OpenAIRE

    Megow Nicole; Vredeveld Tjark

    2009-01-01

    We present constant approximative policies for preemptive stochastic scheduling. We derive policies with a guaranteed performance ratio of 2 for scheduling jobs with release dates on identical parallel machines subject to minimizing the sum of weighted completion times. Our policies as well as their analysis apply also to the recently introduced more general model of stochastic online scheduling. The performance guarantee we give matches the best result known for the corresponding determinist...

  3. Revisiting Symbiotic Job Scheduling

    OpenAIRE

    Eyerman , Stijn; Michaud , Pierre; Rogiest , Wouter

    2015-01-01

    International audience; —Symbiotic job scheduling exploits the fact that in a system with shared resources, the performance of jobs is impacted by the behavior of other co-running jobs. By coscheduling combinations of jobs that have low interference, the performance of a system can be increased. In this paper, we investigate the impact of using symbiotic job scheduling for increasing throughput. We find that even for a theoretically optimal scheduler, this impact is very low, despite the subs...

  4. A Literature Survey for Earliness/Tardiness Scheduling Problems with Learning Effect

    Directory of Open Access Journals (Sweden)

    Mesut Cemil İŞLER

    2009-02-01

    Full Text Available When a task or work is done continuously, there will be an experience so following times needs of required resources (manpower, materials, etc. will be reduced. This learning curve described first by Wright. Wright determined how workmanship costs decreased while proceed plain increasing. This investigations correctness found consistent by plain producers. Learning effect is an effect that, works can be done in shorter time in the rate of repeat of work with repeating same or similar works in production process. Nowadays classical production systems adapted more acceptable systems with new approaches. Just in time production system (JIT philosophy is one of the most important production system philosophies. JIT which is known production without stock stands on using all product resources optimum. Minimization problem of Earliness/Tardiness finishing penalty, which we can describe Just in time scheduling, appeared by inspired from JIT philosophy. In this study, there is literature survey which directed to earliness/tardiness performance criteria and learning effect processing in scheduling and as a result of this it is obtained some establishing for literature.

  5. Automated scheduling and planning from theory to practice

    CERN Document Server

    Ozcan, Ender; Urquhart, Neil

    2013-01-01

      Solving scheduling problems has long presented a challenge for computer scientists and operations researchers. The field continues to expand as researchers and practitioners examine ever more challenging problems and develop automated methods capable of solving them. This book provides 11 case studies in automated scheduling, submitted by leading researchers from across the world. Each case study examines a challenging real-world problem by analysing the problem in detail before investigating how the problem may be solved using state of the art techniques.The areas covered include aircraft scheduling, microprocessor instruction scheduling, sports fixture scheduling, exam scheduling, personnel scheduling and production scheduling.  Problem solving methodologies covered include exact as well as (meta)heuristic approaches, such as local search techniques, linear programming, genetic algorithms and ant colony optimisation.The field of automated scheduling has the potential to impact many aspects of our lives...

  6. Environmental surveillance master sampling schedule

    Energy Technology Data Exchange (ETDEWEB)

    Bisping, L.E.

    1993-01-01

    Environmental surveillance of the Hanford Site and surrounding areas is conducted by the Pacific Northwest Laboratory (PNL) for the US Department of Energy (DOE). Samples are routinely collected and analyzed to determine the quality of air, surface water, ground water, soil, sediment, wildlife, vegetation, foodstuffs, and farm products at Hanford Site and surrounding communities. This document contains the planned schedule for routine sample collection for the Surface Environmental Surveillance Project (SESP) and Drinking Water Project, and Ground-Water Surveillance Project.

  7. Some extensions of the discrete lotsizing and scheduling problem

    NARCIS (Netherlands)

    M. Salomon (Marc); L.G. Kroon (Leo); R. Kuik (Roelof); L.N. van Wassenhove (Luk)

    1991-01-01

    textabstractIn this paper the Discrete Lotsizing and Scheduling Problem (DLSP) is considered. DLSP relates to capacitated lotsizing as well as to job scheduling problems and is concerned with determining a feasible production schedule with minimal total costs in a single-stage manufacturing process.

  8. Alternative Work Schedules: Definitions

    Science.gov (United States)

    Journal of the College and University Personnel Association, 1977

    1977-01-01

    The term "alternative work schedules" encompasses any variation of the requirement that all permanent employees in an organization or one shift of employees adhere to the same five-day, seven-to-eight-hour schedule. This article defines staggered hours, flexible working hours (flexitour and gliding time), compressed work week, the task system, and…

  9. Range Scheduling Aid (RSA)

    Science.gov (United States)

    Logan, J. R.; Pulvermacher, M. K.

    1991-01-01

    Range Scheduling Aid (RSA) is presented in the form of the viewgraphs. The following subject areas are covered: satellite control network; current and new approaches to range scheduling; MITRE tasking; RSA features; RSA display; constraint based analytic capability; RSA architecture; and RSA benefits.

  10. The triangle scheduling problem

    NARCIS (Netherlands)

    Dürr, Christoph; Hanzálek, Zdeněk; Konrad, Christian; Seddik, Yasmina; Sitters, R.A.; Vásquez, Óscar C.; Woeginger, Gerhard

    2017-01-01

    This paper introduces a novel scheduling problem, where jobs occupy a triangular shape on the time line. This problem is motivated by scheduling jobs with different criticality levels. A measure is introduced, namely the binary tree ratio. It is shown that the Greedy algorithm solves the problem to

  11. Shorter Fallow Cycles Affect the Availability of Noncrop Plant Resources in a Shifting Cultivation System

    Directory of Open Access Journals (Sweden)

    Sarah Paule. Dalle

    2006-12-01

    Full Text Available Shifting cultivation systems, one of the most widely distributed forms of agriculture in the tropics, provide not only crops of cultural significance, but also medicinal, edible, ritual, fuel, and forage resources, which contribute to the livelihoods, health, and cultural identity of local people. In many regions across the globe, shifting cultivation systems are undergoing important changes, one of the most pervasive being a shortening of the fallow cycle. Although there has been much attention drawn to declines in crop yields in conjunction with reductions in fallow times, little if any research has focused on the dynamics of noncrop plant resources. In this paper, we use a data set of 26 fields of the same age, i.e., ~1.5 yr, but differing in the length and frequency of past fallow cycles, to examine the impact of shorter fallow periods on the availability of noncrop plant resources. The resources examined are collected in shifting cultivation fields by the Yucatec Maya in Quintana Roo, Mexico. These included firewood, which is cut from remnant trees and stumps spared at the time of felling, and 17 forage species that form part of the weed vegetation. Firewood showed an overall decrease in basal area with shorter fallow cycles, which was mostly related to the smaller diameter of the spared stumps and trees in short-fallow milpas. In contrast, forage species showed a mixed response. Species increasing in abundance in short-fallow milpas tended to be short-lived herbs and shrubs often with weedy habits, whereas those declining in abundance were predominantly pioneer trees and animal-dispersed species. Coppicing tree species showed a neutral response to fallow intensity. Within the cultural and ecological context of our study area, we expect that declines in firewood availability will be most significant for livelihoods because of the high reliance on firewood for local fuel needs and the fact that the main alternative source of firewood, forest

  12. Schedule control in Ling Ao nuclear power project

    International Nuclear Information System (INIS)

    Xie Ahai

    2007-01-01

    Ling Ao Nuclear Power Station (LANP) is first one built up by self-reliance in China with power capacity 990x2 MWe. The results of quality control, schedule control and cost control are satisfactory. The commercial operation days of Unit 1 and Unit 2 were 28th May 2002 and 8th Jan. 2003 respectively, which were 48 days and 66 days in advance of the project schedule. This paper presents the practices of self-reliance schedule control system in LANP. The paper includes 10 sections: schedule control system; targets of schedule control; schedule control at early stage of project; construction schedule; scheduling practice; Point curves; schedule control of design and procurement; a good practice of construction schedule control on site; commissioning and startup schedule; schedule control culture. Three figures are attached. The main contents of the self-reliance schedule control system are as follows: to draw up reasonable schedules and targets; to setup management mechanism and procedures; to organize powerful project management team; to establish close monitoring system; to provide timely progress reports and statistics information. Five kinds of schedule control targets are introduced, i.e. bar-chart schedule; milesones; Point curves; interface management; hydraulic test schedule of auxiliary piping loops; EMR/EMC/EESR issuance schedules. Six levels of bar-chart schedules were adopted in LANP, but the bar-chart schedules were not satisfactory for complicated erection condition on site, even using six levels of schedules. So a kind of Point curves was developed and their advantages are explained. Scheduling method of three elements: activity, duration, logic, which was adopted in LANP, is introduced. The duration of each piping activities in LANP level 2 project schedule was calculated based on the relevant working Point quantities. The analysis and adjustment of Point curves are illustrated, i.e. balance of monthly quantities; possible production in the peakload

  13. Heuristic algorithms for scheduling heat-treatment furnaces of steel ...

    Indian Academy of Sciences (India)

    1Department of Management Studies, Indian Institute of Science,. Bangalore .... and scheduling, production monitoring and data capture, and management information. Southall ...... Project Report, Department of Management Studies, Indian.

  14. NASA Schedule Management Handbook

    Science.gov (United States)

    2011-01-01

    The purpose of schedule management is to provide the framework for time-phasing, resource planning, coordination, and communicating the necessary tasks within a work effort. The intent is to improve schedule management by providing recommended concepts, processes, and techniques used within the Agency and private industry. The intended function of this handbook is two-fold: first, to provide guidance for meeting the scheduling requirements contained in NPR 7120.5, NASA Space Flight Program and Project Management Requirements, NPR 7120.7, NASA Information Technology and Institutional Infrastructure Program and Project Requirements, NPR 7120.8, NASA Research and Technology Program and Project Management Requirements, and NPD 1000.5, Policy for NASA Acquisition. The second function is to describe the schedule management approach and the recommended best practices for carrying out this project control function. With regards to the above project management requirements documents, it should be noted that those space flight projects previously established and approved under the guidance of prior versions of NPR 7120.5 will continue to comply with those requirements until project completion has been achieved. This handbook will be updated as needed, to enhance efficient and effective schedule management across the Agency. It is acknowledged that most, if not all, external organizations participating in NASA programs/projects will have their own internal schedule management documents. Issues that arise from conflicting schedule guidance will be resolved on a case by case basis as contracts and partnering relationships are established. It is also acknowledged and understood that all projects are not the same and may require different levels of schedule visibility, scrutiny and control. Project type, value, and complexity are factors that typically dictate which schedule management practices should be employed.

  15. The robust schedule - A link to improved workflow

    DEFF Research Database (Denmark)

    Lindhard, Søren; Wandahl, Søren

    2012-01-01

    -down the contractors, and force them to rigorously adhere to the initial schedule. If delayed the work-pace or manpower has to be increased to observe the schedule. In attempt to improve productivity three independent site-mangers have been interviewed about time-scheduling. Their experiences and opinions have been...... analyzed and weaknesses in existing time scheduling have been found. The findings showed a negative side effect of keeping the schedule to tight. A too tight schedule is inflexible and cannot absorb variability in production. Flexibility is necessary because of the contractors interacting and dependable....... The result is a chaotic, complex and uncontrolled construction site. Furthermore, strict time limits entail the workflow to be optimized under non-optimal conditions. Even though productivity seems to be increasing, productivity per man-hour is decreasing resulting in increased cost. To increase productivity...

  16. Physician Fee Schedule Search

    Data.gov (United States)

    U.S. Department of Health & Human Services — This website is designed to provide information on services covered by the Medicare Physician Fee Schedule (MPFS). It provides more than 10,000 physician services,...

  17. Clinical Laboratory Fee Schedule

    Data.gov (United States)

    U.S. Department of Health & Human Services — Outpatient clinical laboratory services are paid based on a fee schedule in accordance with Section 1833(h) of the Social Security Act. The clinical laboratory fee...

  18. CERN confirms LHC schedule

    CERN Document Server

    2003-01-01

    The CERN Council held its 125th session on 20 June. Highlights of the meeting included confirmation that the LHC is on schedule for a 2007 start-up, and the announcement of a new organizational structure in 2004.

  19. DMEPOS Fee Schedule

    Data.gov (United States)

    U.S. Department of Health & Human Services — The list contains the fee schedule amounts, floors, and ceilings for all procedure codes and payment category, jurisdication, and short description assigned to each...

  20. Project Schedule Simulation

    DEFF Research Database (Denmark)

    Mizouni, Rabeb; Lazarova-Molnar, Sanja

    2015-01-01

    overrun both their budget and time. To improve the quality of initial project plans, we show in this paper the importance of (1) reflecting features’ priorities/risk in task schedules and (2) considering uncertainties related to human factors in plan schedules. To make simulation tasks reflect features......’ priority as well as multimodal team allocation, enhanced project schedules (EPS), where remedial actions scenarios (RAS) are added, were introduced. They reflect potential schedule modifications in case of uncertainties and promote a dynamic sequencing of involved tasks rather than the static conventional...... this document as an instruction set. The electronic file of your paper will be formatted further at Journal of Software. Define all symbols used in the abstract. Do not cite references in the abstract. Do not delete the blank line immediately above the abstract; it sets the footnote at the bottom of this column....

  1. Decentralized Ground Staff Scheduling

    DEFF Research Database (Denmark)

    Sørensen, M. D.; Clausen, Jens

    2002-01-01

    scheduling is investigated. The airport terminal is divided into zones, where each zone consists of a set of stands geographically next to each other. Staff is assigned to work in only one zone and the staff scheduling is planned decentralized for each zone. The advantage of this approach is that the staff...... work in a smaller area of the terminal and thus spends less time walking between stands. When planning decentralized the allocation of stands to flights influences the staff scheduling since the workload in a zone depends on which flights are allocated to stands in the zone. Hence solving the problem...... depends on the actual stand allocation but also on the number of zones and the layout of these. A mathematical model of the problem is proposed, which integrates the stand allocation and the staff scheduling. A heuristic solution method is developed and applied on a real case from British Airways, London...

  2. Fee Schedules - General Information

    Data.gov (United States)

    U.S. Department of Health & Human Services — A fee schedule is a complete listing of fees used by Medicare to pay doctors or other providers-suppliers. This comprehensive listing of fee maximums is used to...

  3. CMS Records Schedule

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CMS Records Schedule provides disposition authorizations approved by the National Archives and Records Administration (NARA) for CMS program-related records...

  4. Patients' preference for radiotherapy fractionation schedule in the palliation of symptomatic unresectable lung cancer

    International Nuclear Information System (INIS)

    Tang, J. I.; Lu, J. J.; Wong, L. C.

    2008-01-01

    Full text: The palliative radiotherapeutic management of unresectable non-small-cell lung cancer is controversial, with various fractionation (F x) schedules available. We aimed to determine patient's choice of F x schedule after involvement in a decision-making process using a decision board. A decision board outlining the various advantages and disadvantages apparent in the Medical Research Council study of F x schedules (17 Gy in two fractions vs 39 Gy in 13 fractions) was discussed with patients who met Medical Research Council eligibility criteria. Patients were then asked to indicate their preferred F x schedules, reasons and their level of satisfaction with being involved in the decision making process. Radiation oncologists (R O ) could prescribe radiotherapy schedules irrespective of patients' preferences. Of 92 patients enrolled, 55% chose the longer schedule. English-speaking patients were significantly more likely to choose the longer schedule (P 0.02, 95% confidence interval: 1.2-7.6). Longer F x was chosen because of longer survival (90%) and better local control (12%). Shorter F x was chosen for shorter overall treatment duration (80%), cost (61%) and better symptom control (20%). In all, 56% of patients choosing the shorter schedule had their treatment altered by the treating R O , whereas only 4% of patients choosing longer F x had their treatment altered (P O 's own biases.

  5. Statistical modelling for precision agriculture: A case study in optimal environmental schedules for Agaricus Bisporus production via variable domain functional regression

    Science.gov (United States)

    Panayi, Efstathios; Kyriakides, George

    2017-01-01

    Quantifying the effects of environmental factors over the duration of the growing process on Agaricus Bisporus (button mushroom) yields has been difficult, as common functional data analysis approaches require fixed length functional data. The data available from commercial growers, however, is of variable duration, due to commercial considerations. We employ a recently proposed regression technique termed Variable-Domain Functional Regression in order to be able to accommodate these irregular-length datasets. In this way, we are able to quantify the contribution of covariates such as temperature, humidity and water spraying volumes across the growing process, and for different lengths of growing processes. Our results indicate that optimal oxygen and temperature levels vary across the growing cycle and we propose environmental schedules for these covariates to optimise overall yields. PMID:28961254

  6. Constraint-based job shop scheduling with ILOG SCHEDULER

    NARCIS (Netherlands)

    Nuijten, W.P.M.; Le Pape, C.

    1998-01-01

    We introduce constraint-based scheduling and discuss its main principles. An approximation algorithm based on tree search is developed for the job shop scheduling problem using ILOG SCHEDULER. A new way of calculating lower bounds on the makespan of the job shop scheduling problem is presented and

  7. Planning and scheduling - A schedule's performance

    International Nuclear Information System (INIS)

    Whitman, N.M.

    1993-01-01

    Planning and scheduling is a process whose time has come to PSI Energy. With an awareness of the challenges ahead, individuals must look for ways to enhance the corporate competitiveness. Working toward this goal means that each individual has to dedicate themselves to this more competitive corporate environment. Being competitive may be defined as the ability of each employee to add value to the corporation's economic well being. The timely and successful implementation of projects greatly enhances competitiveness. Those projects that do not do well often suffer from lack of proper execution - not for lack of talent or strategic vision. Projects are consumers of resources such as cash and people. They produce a return when completed and will generate a better return when properly completed utilizing proven project management techniques. Completing projects on time, within budget and meeting customer expectations is the way a corporation builds it's future. This paper offers suggestions on implementing planning and scheduling and provides a review of results in the form of management reports

  8. Environmental surveillance master sampling schedule

    International Nuclear Information System (INIS)

    Bisping, L.E.

    1995-02-01

    Environmental surveillance of the Hanford Site and surrounding areas is conducted by the Pacific Northwest Laboratory (PNL) for the U.S. Department of Energy (DOE). This document contains the planned 1994 schedules for routine collection of samples for the Surface Environmental Surveillance Project (SESP), Drinking Water Project, and Ground-Water Surveillance Project. Samples are routinely collected for the SESP and analyzed to determine the quality of air, surface water, soil, sediment, wildlife, vegetation, foodstuffs, and farm products at Hanford Site and surrounding communities. The responsibility for monitoring onsite drinking water falls outside the scope of the SESP. PNL conducts the drinking water monitoring project concurrent with the SESP to promote efficiency and consistency, utilize expertise developed over the years, and reduce costs associated with management, procedure development, data management, quality control, and reporting. The ground-water sampling schedule identifies ground-water sampling .events used by PNL for environmental surveillance of the Hanford Site. Sampling is indicated as annual, semi-annual, quarterly, or monthly in the sampling schedule. Some samples are collected and analyzed as part of ground-water monitoring and characterization programs at Hanford (e.g. Resources Conservation and Recovery Act (RCRA), Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), or Operational). The number of samples planned by other programs are identified in the sampling schedule by a number in the analysis column and a project designation in the Cosample column. Well sampling events may be merged to avoid redundancy in cases where sampling is planned by both-environmental surveillance and another program

  9. Environmental surveillance master sampling schedule

    Energy Technology Data Exchange (ETDEWEB)

    Bisping, L.E.

    1995-02-01

    Environmental surveillance of the Hanford Site and surrounding areas is conducted by the Pacific Northwest Laboratory (PNL) for the U.S. Department of Energy (DOE). This document contains the planned 1994 schedules for routine collection of samples for the Surface Environmental Surveillance Project (SESP), Drinking Water Project, and Ground-Water Surveillance Project. Samples are routinely collected for the SESP and analyzed to determine the quality of air, surface water, soil, sediment, wildlife, vegetation, foodstuffs, and farm products at Hanford Site and surrounding communities. The responsibility for monitoring onsite drinking water falls outside the scope of the SESP. PNL conducts the drinking water monitoring project concurrent with the SESP to promote efficiency and consistency, utilize expertise developed over the years, and reduce costs associated with management, procedure development, data management, quality control, and reporting. The ground-water sampling schedule identifies ground-water sampling .events used by PNL for environmental surveillance of the Hanford Site. Sampling is indicated as annual, semi-annual, quarterly, or monthly in the sampling schedule. Some samples are collected and analyzed as part of ground-water monitoring and characterization programs at Hanford (e.g. Resources Conservation and Recovery Act (RCRA), Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), or Operational). The number of samples planned by other programs are identified in the sampling schedule by a number in the analysis column and a project designation in the Cosample column. Well sampling events may be merged to avoid redundancy in cases where sampling is planned by both-environmental surveillance and another program.

  10. Shorter height is related to lower cardiovascular disease risk – A narrative review

    Directory of Open Access Journals (Sweden)

    Thomas T. Samaras

    2013-01-01

    Full Text Available Numerous Western studies have shown a negative correlation between height and cardiovascular disease. However, these correlations do not prove causation. This review provides a variety of studies showing short people have little to no cardiovascular disease. When shorter people are compared to taller people, a number of biological mechanisms evolve favoring shorter people, including reduced telomere shortening, lower atrial fibrillation, higher heart pumping efficiency, lower DNA damage, lower risk of blood clots, lower left ventricular hypertrophy and superior blood parameters. The causes of increased heart disease among shorter people in the developed world are related to lower income, excessive weight, poor diet, lifestyle factors, catch-up growth, childhood illness and poor environmental conditions. For short people in developed countries, the data indicate that a plant-based diet, leanness and regular exercise can substantially reduce the risk of cardiovascular disease.

  11. Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants

    Science.gov (United States)

    Fisher, B.G.; Thankamony, A.; Hughes, I.A.; Ong, K.K.; Dunger, D.B.; Acerini, C.L.

    2016-01-01

    STUDY QUESTION What is the relationship between maternal paracetamol intake during the masculinisation programming window (MPW, 8–14 weeks of gestation) and male infant anogenital distance (AGD), a biomarker for androgen action during the MPW? SUMMARY ANSWER Intrauterine paracetamol exposure during 8–14 weeks of gestation is associated with shorter AGD from birth to 24 months of age. WHAT IS ALREADY KNOWN The increasing prevalence of male reproductive disorders may reflect environmental influences on foetal testicular development during the MPW. Animal and human xenograft studies have demonstrated that paracetamol reduces foetal testicular testosterone production, consistent with reported epidemiological associations between prenatal paracetamol exposure and cryptorchidism. STUDY DESIGN, SIZE, DURATION Prospective cohort study (Cambridge Baby Growth Study), with recruitment of pregnant women at ~12 post-menstrual weeks of gestation from a single UK maternity unit between 2001 and 2009, and 24 months of infant follow-up. Of 2229 recruited women, 1640 continued with the infancy study after delivery, of whom 676 delivered male infants and completed a medicine consumption questionnaire. PARTICIPANTS/MATERIALS, SETTING, METHOD Mothers self-reported medicine consumption during pregnancy by a questionnaire administered during the perinatal period. Infant AGD (measured from 2006 onwards), penile length and testicular descent were assessed at 0, 3, 12, 18 and 24 months of age, and age-specific Z scores were calculated. Associations between paracetamol intake during three gestational periods (14 weeks) and these outcomes were tested by linear mixed models. Two hundred and twenty-five (33%) of six hundred and eighty-one male infants were exposed to paracetamol during pregnancy, of whom sixty-eight were reported to be exposed during 8–14 weeks. AGD measurements were available for 434 male infants. MAIN RESULTS AND THE ROLE OF CHANCE Paracetamol exposure during 8–14

  12. Integrated Job Scheduling and Network Routing

    DEFF Research Database (Denmark)

    Gamst, Mette; Pisinger, David

    2013-01-01

    We consider an integrated job scheduling and network routing problem which appears in Grid Computing and production planning. The problem is to schedule a number of jobs at a finite set of machines, such that the overall profit of the executed jobs is maximized. Each job demands a number of resou...... indicate that the algorithm can be used as an actual scheduling algorithm in the Grid or as a tool for analyzing Grid performance when adding extra machines or jobs. © 2012 Wiley Periodicals, Inc.......We consider an integrated job scheduling and network routing problem which appears in Grid Computing and production planning. The problem is to schedule a number of jobs at a finite set of machines, such that the overall profit of the executed jobs is maximized. Each job demands a number...... of resources which must be sent to the executing machine through a network with limited capacity. A job cannot start before all of its resources have arrived at the machine. The scheduling problem is formulated as a Mixed Integer Program (MIP) and proved to be NP-hard. An exact solution approach using Dantzig...

  13. Constraint-based scheduling

    Science.gov (United States)

    Zweben, Monte

    1993-01-01

    The GERRY scheduling system developed by NASA Ames with assistance from the Lockheed Space Operations Company, and the Lockheed Artificial Intelligence Center, uses a method called constraint-based iterative repair. Using this technique, one encodes both hard rules and preference criteria into data structures called constraints. GERRY repeatedly attempts to improve schedules by seeking repairs for violated constraints. The system provides a general scheduling framework which is being tested on two NASA applications. The larger of the two is the Space Shuttle Ground Processing problem which entails the scheduling of all the inspection, repair, and maintenance tasks required to prepare the orbiter for flight. The other application involves power allocation for the NASA Ames wind tunnels. Here the system will be used to schedule wind tunnel tests with the goal of minimizing power costs. In this paper, we describe the GERRY system and its application to the Space Shuttle problem. We also speculate as to how the system would be used for manufacturing, transportation, and military problems.

  14. Scheduling job shop - A case study

    Science.gov (United States)

    Abas, M.; Abbas, A.; Khan, W. A.

    2016-08-01

    The scheduling in job shop is important for efficient utilization of machines in the manufacturing industry. There are number of algorithms available for scheduling of jobs which depend on machines tools, indirect consumables and jobs which are to be processed. In this paper a case study is presented for scheduling of jobs when parts are treated on available machines. Through time and motion study setup time and operation time are measured as total processing time for variety of products having different manufacturing processes. Based on due dates different level of priority are assigned to the jobs and the jobs are scheduled on the basis of priority. In view of the measured processing time, the times for processing of some new jobs are estimated and for efficient utilization of the machines available an algorithm is proposed and validated.

  15. Step-by-step cyclic processes scheduling

    DEFF Research Database (Denmark)

    Bocewicz, G.; Nielsen, Izabela Ewa; Banaszak, Z.

    2013-01-01

    Automated Guided Vehicles (AGVs) fleet scheduling is one of the big problems in Flexible Manufacturing System (FMS) control. The problem is more complicated when concurrent multi-product manufacturing and resource deadlock avoidance policies are considered. The objective of the research is to pro......Automated Guided Vehicles (AGVs) fleet scheduling is one of the big problems in Flexible Manufacturing System (FMS) control. The problem is more complicated when concurrent multi-product manufacturing and resource deadlock avoidance policies are considered. The objective of the research...... is to provide a declarative model enabling to state a constraint satisfaction problem aimed at AGVs fleet scheduling subject to assumed itineraries of concurrently manufactured product types. In other words, assuming a given layout of FMS’s material handling and production routes of simultaneously manufactured...... orders, the main objective is to provide the declarative framework aimed at conditions allowing one to calculate the AGVs fleet schedule in online mode. An illustrative example of the relevant algebra-like driven step-by-stem cyclic scheduling is provided....

  16. Online scheduling of 2-re-entrant flexible manufacturing systems

    NARCIS (Netherlands)

    Pinxten, J. van; Waqas, U.; Geilen, M.; Basten, T.; Somers, L.

    2017-01-01

    Online scheduling of operations is essential to optimize productivity of flexible manufacturing systems (FMSs) where manufacturing requests arrive on the fly. An FMS processes products according to a particular flow through processing stations. This work focusses on online scheduling of re-entrant

  17. Estimating exponential scheduling preferences

    DEFF Research Database (Denmark)

    Hjorth, Katrine; Börjesson, Maria; Engelson, Leonid

    2015-01-01

    of car drivers' route and mode choice under uncertain travel times. Our analysis exposes some important methodological issues related to complex non-linear scheduling models: One issue is identifying the point in time where the marginal utility of being at the destination becomes larger than the marginal......Different assumptions about travelers' scheduling preferences yield different measures of the cost of travel time variability. Only few forms of scheduling preferences provide non-trivial measures which are additive over links in transport networks where link travel times are arbitrarily...... utility of being at the origin. Another issue is that models with the exponential marginal utility formulation suffer from empirical identification problems. Though our results are not decisive, they partly support the constant-affine specification, in which the value of travel time variability...

  18. Post LS1 schedule

    CERN Document Server

    Lamont, M

    2014-01-01

    The scheduling limits for a typical long year taking into account technical stops, machine development, spe- cial physics runs are presented. An attempt is then made to outline a ten year post LS1 schedule taking into account the disparate requirements outlined in the previous talks in this session. The demands on the planned long shutdowns and the impact of these demands on their proposed length will be discussed. The option of using ion running as a pre-shutdown cool-down period will be addressed.

  19. Predicting Exposure to Consumer-Products Using Agent-Based Models Embedded with Needs-Based Artificial Intelligence and Empirically -Based Scheduling Models

    Science.gov (United States)

    Information on human behavior and consumer product use is important for characterizing exposures to chemicals in consumer products and in indoor environments. Traditionally, exposure-assessors have relied on time-use surveys to obtain information on exposure-related behavior. In ...

  20. Developing optimal nurses work schedule using integer programming

    Science.gov (United States)

    Shahidin, Ainon Mardhiyah; Said, Mohd Syazwan Md; Said, Noor Hizwan Mohamad; Sazali, Noor Izatie Amaliena

    2017-08-01

    Time management is the art of arranging, organizing and scheduling one's time for the purpose of generating more effective work and productivity. Scheduling is the process of deciding how to commit resources between varieties of possible tasks. Thus, it is crucial for every organization to have a good work schedule for their staffs. The job of Ward nurses at hospitals runs for 24 hours every day. Therefore, nurses will be working using shift scheduling. This study is aimed to solve the nurse scheduling problem at an emergency ward of a private hospital. A 7-day work schedule for 7 consecutive weeks satisfying all the constraints set by the hospital will be developed using Integer Programming. The work schedule for the nurses obtained gives an optimal solution where all the constraints are being satisfied successfully.

  1. GRASP (Greedy Randomized Adaptive Search Procedures) applied to optimization of petroleum products distribution in pipeline networks; GRASP (Greedy Randomized Adaptative Search Procedures) aplicado ao 'scheduling' de redes de distribuicao de petroleo e derivados

    Energy Technology Data Exchange (ETDEWEB)

    Conte, Viviane Cristhyne Bini; Arruda, Lucia Valeria Ramos de; Yamamoto, Lia [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil)

    2008-07-01

    Planning and scheduling of the pipeline network operations aim the most efficient use of the resources resulting in a better performance of the network. A petroleum distribution pipeline network is composed by refineries, sources and/or storage parks, connected by a set of pipelines, which operate the transportation of petroleum and derivatives among adjacent areas. In real scenes, this problem is considered a combinatorial problem, which has difficult solution, which makes necessary methodologies of the resolution that present low computational time. This work aims to get solutions that attempt the demands and minimize the number of batch fragmentations on the sent operations of products for the pipelines in a simplified model of a real network, through by application of the local search metaheuristic GRASP. GRASP does not depend of solutions of previous iterations and works in a random way so it allows the search for the solution in an ampler and diversified search space. GRASP utilization does not demand complex calculation, even the construction stage that requires more computational effort, which provides relative rapidity in the attainment of good solutions. GRASP application on the scheduling of the operations of this network presented feasible solutions in a low computational time. (author)

  2. CMS multicore scheduling strategy

    International Nuclear Information System (INIS)

    Yzquierdo, Antonio Pérez-Calero; Hernández, Jose; Holzman, Burt; Majewski, Krista; McCrea, Alison

    2014-01-01

    In the next years, processor architectures based on much larger numbers of cores will be most likely the model to continue 'Moore's Law' style throughput gains. This not only results in many more jobs in parallel running the LHC Run 1 era monolithic applications, but also the memory requirements of these processes push the workernode architectures to the limit. One solution is parallelizing the application itself, through forking and memory sharing or through threaded frameworks. CMS is following all of these approaches and has a comprehensive strategy to schedule multicore jobs on the GRID based on the glideinWMS submission infrastructure. The main component of the scheduling strategy, a pilot-based model with dynamic partitioning of resources that allows the transition to multicore or whole-node scheduling without disallowing the use of single-core jobs, is described. This contribution also presents the experiences made with the proposed multicore scheduling schema and gives an outlook of further developments working towards the restart of the LHC in 2015.

  3. Harmonious personnel scheduling

    NARCIS (Netherlands)

    Fijn van Draat, Laurens; Post, Gerhard F.; Veltman, Bart; Winkelhuijzen, Wessel

    2006-01-01

    The area of personnel scheduling is very broad. Here we focus on the ‘shift assignment problem’. Our aim is to discuss how ORTEC HARMONY handles this planning problem. In particular we go into the structure of the optimization engine in ORTEC HARMONY, which uses techniques from genetic algorithms,

  4. Hybrid job shop scheduling

    NARCIS (Netherlands)

    Schutten, Johannes M.J.

    1995-01-01

    We consider the problem of scheduling jobs in a hybrid job shop. We use the term 'hybrid' to indicate that we consider a lot of extensions of the classic job shop, such as transportation times, multiple resources, and setup times. The Shifting Bottleneck procedure can be generalized to deal with

  5. Practical job shop scheduling

    NARCIS (Netherlands)

    Schutten, Johannes M.J.

    1998-01-01

    The Shifting Bottleneck procedure is an intuitive and reasonably good approximation algorithm for the notoriously difficult classical job shop scheduling problem. The principle of decomposing a classical job shop problem into a series of single-machine problems can also easily be applied to job shop

  6. "Creative" Work Schedules.

    Science.gov (United States)

    Blai, Boris

    Many creative or flexible work scheduling options are becoming available to the many working parents, students, handicapped persons, elderly individuals, and others who are either unable or unwilling to work a customary 40-hour work week. These options may be broadly categorized as either restructured or reduced work time options. The three main…

  7. Plan maestro de producción basado en programación lineal entera para una empresa de productos químicos || Master Production Scheduling Based on Integer Linear Programming for a Chemical Company

    Directory of Open Access Journals (Sweden)

    Reyes Zotelo, Yunuem

    2017-12-01

    Full Text Available En este trabajo se propone un modelo de programación lineal entera para planificar la producción de un conjunto de artículos finales con demanda independiente. El modelo para la planificación maestra de producción (PMP está diseñado considerando los costes de producción e inventario, así como las restricciones definidas por el mismo proceso productivo en cuanto a instalaciones y tiempos de producción. El objetivo del modelo propuesto es la minimización de los costes implicados; concretamente, el tiempo ocioso y extra de los recursos, así como la consideración de un nivel mínimo de servicio ligado a la demanda diferida. La validación del modelo considera datos pertenecientes a la demanda de cada producto en un horizonte de 12 semanas y compara cinco escenarios en los que se modifican algunos aspectos del sistema y diferentes niveles de servicio. Por último, los resultados obtenidos para cada uno de los escenarios exponen la mejora obtenida por el modelo propuesto respecto al procedimiento actual en la empresa objeto de estudio. || In this work, we propose an integer linear programming model for production scheduling of a group of finished products with independent demand. The model for the master production scheduling (MPS is designed by considering production and inventory costs, as well as the productive process constraints regarding installations and production times. The aim of the proposed model is the minimization of the costs involved; specifically, undertime and overtime costs of resources, as well as the consideration of a minimum service level related to the deferred demand. The validation of the model considers data belonging to the demand of each product in a 12-week planning horizon and compares five scenarios in which some characteristics of the system and different service levels are modified. Finally, the results obtained for each one of the scenarios expose the improvement obtained by the proposed model with

  8. Environmental surveillance master sampling schedule

    Energy Technology Data Exchange (ETDEWEB)

    Bisping, L E

    1992-01-01

    Environmental surveillance of the Hanford Site and surrounding areas is conducted by the Pacific Northwest Laboratory (PNL) for the US Department of Energy (DOE). This document contains the planned schedule for routine sample collection for the Surface Environmental Surveillance Project (SESP) and Ground-Water Monitoring Project. Samples for radiological analyses include Air-Particulate Filter, gases and vapor; Water/Columbia River, Onsite Pond, Spring, Irrigation, and Drinking; Foodstuffs/Animal Products including Whole Milk, Poultry and Eggs, and Beef; Foodstuffs/Produce including Leafy Vegetables, Vegetables, and Fruit; Foodstuffs/Farm Products including Wine, Wheat and Alfalfa; Wildlife; Soil; Vegetation; and Sediment. Direct Radiation Measurements include Terrestrial Locations, Columbia River Shoreline Locations, and Onsite Roadway, Railway and Aerial, Radiation Surveys.

  9. Extending 3D near-cloud corrections from shorter to longer wavelengths

    International Nuclear Information System (INIS)

    Marshak, Alexander; Evans, K. Frank; Várnai, Tamás; Wen, Guoyong

    2014-01-01

    Satellite observations have shown a positive correlation between cloud amount and aerosol optical thickness (AOT) that can be explained by the humidification of aerosols near clouds, and/or by cloud contamination by sub-pixel size clouds and the cloud adjacency effect. The last effect may substantially increase reflected radiation in cloud-free columns, leading to overestimates in the retrieved AOT. For clear-sky areas near boundary layer clouds the main contribution to the enhancement of clear sky reflectance at shorter wavelengths comes from the radiation scattered into clear areas by clouds and then scattered to the sensor by air molecules. Because of the wavelength dependence of air molecule scattering, this process leads to a larger reflectance increase at shorter wavelengths, and can be corrected using a simple two-layer model [18]. However, correcting only for molecular scattering skews spectral properties of the retrieved AOT. Kassianov and Ovtchinnikov [9] proposed a technique that uses spectral reflectance ratios to retrieve AOT in the vicinity of clouds; they assumed that the cloud adjacency effect influences the spectral ratio between reflectances at two wavelengths less than it influences the reflectances themselves. This paper combines the two approaches: It assumes that the 3D correction for the shortest wavelength is known with some uncertainties, and then it estimates the 3D correction for longer wavelengths using a modified ratio method. The new approach is tested with 3D radiances simulated for 26 cumulus fields from Large-Eddy Simulations, supplemented with 40 aerosol profiles. The results showed that (i) for a variety of cumulus cloud scenes and aerosol profiles over ocean the 3D correction due to cloud adjacency effect can be extended from shorter to longer wavelengths and (ii) the 3D corrections for longer wavelengths are not very sensitive to unbiased random uncertainties in the 3D corrections at shorter wavelengths. - Highlights:

  10. A Gas Scheduling Optimization Model for Steel Enterprises

    Directory of Open Access Journals (Sweden)

    Niu Honghai

    2017-01-01

    Full Text Available Regarding the scheduling problems of steel enterprises, this research designs the gas scheduling optimization model according to the rules and priorities. Considering different features and the process changes of the gas unit in the process of actual production, the calculation model of process state and gas consumption soft measurement together with the rules of scheduling optimization is proposed to provide the dispatchers with real-time gas using status of each process, then help them to timely schedule and reduce the gas volume fluctuations. In the meantime, operation forewarning and alarm functions are provided to avoid the abnormal situation in the scheduling, which has brought about very good application effect in the actual scheduling and ensures the safety of the gas pipe network system and the production stability.

  11. Evaluation of using cyclocranes to support drilling & production of oil & gas in wetland areas. Sixth quarterly technical progress report, incorporating milestone schedule/status, October 1993--December 1993

    Energy Technology Data Exchange (ETDEWEB)

    Eggington, W.J.

    1994-04-01

    This report is a progress report on a planned program falling under wetlands area research related to drilling, production, and transportation of oil and gas resources. Specifically the planned program addresses an evaluation of using cyclocraft to transport drill rigs, mud, pipes and other materials and equipment in a cost effective and environmentally safe manner to support oil and gas drilling and production operations in wetland areas. During this period, task 5, subscale tests, and task 7, environmental impacts, were completed. Work was continued on task 10, technology transfer, and the preparation of the final report as part of task 11.

  12. YAOPBM-II: extension to higher degrees and to shorter time series

    Energy Technology Data Exchange (ETDEWEB)

    Korzennik, S G [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (United States)], E-mail: skorzennik@cfa.harvard.edu

    2008-10-15

    In 2005, I presented a new fitting methodology (Yet AnOther Peak Bagging Method -YAOPBM), derived for very-long time series (2088-day-long) and applied it to low degree modes, {iota} {<=} 25. That very-long time series was also sub-divided into shorter segments (728-day-long) that were each fitted over the same range of degrees, to estimate changes with solar activity levels. I present here the extension of this method in several 'directions': a) to substantially higher degrees ({iota} {<=} 125); b) to shorter time series (364- and 182-day-long); and c) to additional 728-day-long segments, covering now some 10 years of observations. I discuss issues with the fitting, namely the leakage matrix, and the f- and p1 mode at very low frequencies, and I present some of the characteristics of the observed temporal changes.

  13. Flow-shop scheduling problem under uncertainties: Review and trends

    OpenAIRE

    Eliana María González-Neira; Jairo R. Montoya-Torres; David Barrera

    2017-01-01

    Among the different tasks in production logistics, job scheduling is one of the most important at the operational decision-making level to enable organizations to achieve competiveness. Scheduling consists in the allocation of limited resources to activities over time in order to achieve one or more optimization objectives. Flow-shop (FS) scheduling problems encompass the sequencing processes in environments in which the activities or operations are performed in a serial flow. This type of co...

  14. Is equity confined to the shorter term projects - and if not, what does it need?

    International Nuclear Information System (INIS)

    Cryan, T.

    1996-01-01

    There are two types of equity investor generally found in shorter term energy projects: energy project developers or sponsors who view a given project as buying or building a business; and financial investors who have viewed an investment as buying a stream of cash flows. This article examines the objectives and needs of these two investor groups, and discusses the principal issues which govern their respective decision-making process. (author)

  15. How do shorter working hours affect employee wellbeing? : Shortening working time in Finland

    OpenAIRE

    Lahdenperä, Netta

    2017-01-01

    The way work is done is dramatically changing due to digital breakthroughs. Generation Y is entering the workforce with a changed attitude towards work as organizations are increasing their focus towards employee wellbeing. Organizations who adopt the new model of work and understand the importance of the wellbeing of their staff are leading the transition to a more efficient business, better working life and a healthier planet. The thesis explores the numerous effects of shorter working...

  16. GLOA: A New Job Scheduling Algorithm for Grid Computing

    Directory of Open Access Journals (Sweden)

    Zahra Pooranian

    2013-03-01

    Full Text Available The purpose of grid computing is to produce a virtual supercomputer by using free resources available through widespread networks such as the Internet. This resource distribution, changes in resource availability, and an unreliable communication infrastructure pose a major challenge for efficient resource allocation. Because of the geographical spread of resources and their distributed management, grid scheduling is considered to be a NP-complete problem. It has been shown that evolutionary algorithms offer good performance for grid scheduling. This article uses a new evaluation (distributed algorithm inspired by the effect of leaders in social groups, the group leaders' optimization algorithm (GLOA, to solve the problem of scheduling independent tasks in a grid computing system. Simulation results comparing GLOA with several other evaluation algorithms show that GLOA produces shorter makespans.

  17. Scheduling techniques in the Request Oriented Scheduling Engine (ROSE)

    Science.gov (United States)

    Zoch, David R.

    1991-01-01

    Scheduling techniques in the ROSE are presented in the form of the viewgraphs. The following subject areas are covered: agenda; ROSE summary and history; NCC-ROSE task goals; accomplishments; ROSE timeline manager; scheduling concerns; current and ROSE approaches; initial scheduling; BFSSE overview and example; and summary.

  18. Location-based Scheduling

    DEFF Research Database (Denmark)

    Andersson, Niclas; Christensen, Knud

    on the market. However, CPM is primarily an activity based method that takes the activity as the unit of focus and there is criticism raised, specifically in the case of construction projects, on the method for deficient management of construction work and continuous flow of resources. To seek solutions...... to the identified limitations of the CPM method, an alternative planning and scheduling methodology that includes locations is tested. Location-based Scheduling (LBS) implies a shift in focus, from primarily the activities to the flow of work through the various locations of the project, i.e. the building. LBS uses...... the graphical presentation technique of Line-of-balance, which is adapted for planning and management of work-flows that facilitates resources to perform their work without interruptions caused by other resources working with other activities in the same location. As such, LBS and Lean Construction share...

  19. Crane Scheduling on a Plate Storage

    DEFF Research Database (Denmark)

    Hansen, Jesper

    2002-01-01

    OSS produces the worlds largest container ships. The first process of producing the steel ships is handling arrival and storage of steel plates until they are needed in production. Two gantry cranes carry out this task. The planning task is now to create a schedule of movements for the 2 cranes...

  20. DEVELOPMENT OF A MAINTENANCE SCHEDULING MODEL FOR ...

    African Journals Online (AJOL)

    ... of minor maintenance, for each machine within this time span. In order to minimize the total cost of repairs and production. A numerical application of this development model in a case study is presented. Key words: Maintenance, modeling, scheduling, optimization. [Global Jnl Engineering Res. Vol.1(2) 2002: 107-118] ...

  1. Modelling altered fractionation schedules

    International Nuclear Information System (INIS)

    Fowler, J.F.

    1993-01-01

    The author discusses the conflicting requirements of hyperfractionation and accelerated fractionation used in radiotherapy, and the development of computer modelling to predict how to obtain an optimum of tumour cell kill without exceeding normal-tissue tolerance. The present trend is to shorten hyperfractionated schedules from 6 or 7 weeks to give overall times of 4 or 5 weeks as in new schedules by Herskovic et al (1992) and Harari (1992). Very high doses are given, much higher than can be given when ultrashort schedules such as CHART (12 days) are used. Computer modelling has suggested that optimum overall times, to yield maximum cell kill in tumours ((α/β = 10 Gy) for a constant level of late complications (α/β = 3 Gy) would be X or X-1 weeks, where X is the doubling time of the tumour cells in days (Fowler 1990). For median doubling times of about 5 days, overall times of 4 or 5 weeks should be ideal. (U.K.)

  2. Estimating exponential scheduling preferences

    DEFF Research Database (Denmark)

    Hjorth, Katrine; Börjesson, Maria; Engelson, Leonid

    Extended abstract Choice of departure time is a travel choice dimension that transportation planners often need to forecast in appraisal. A traveller may shift departure time in response to changes in expected travel time or travel time variability (TTV) or in response to time-differentiated cong......Extended abstract Choice of departure time is a travel choice dimension that transportation planners often need to forecast in appraisal. A traveller may shift departure time in response to changes in expected travel time or travel time variability (TTV) or in response to time...... from the underlying scheduling preferences (Noland and Small, 1995, Bates et al., 2001, Fosgerau and Karlström, 2010). The scheduling preferences can be formally represented as time-dependent rates of utility derived at different locations. Assuming that the travellers are rational and choose departure......’ departure time choice. The assumption underlying the scheduling approach is that the traveller rationally maximises her total utility obtained during a period of time. The total utility depends on time of departure from the origin and time of arrival to the destination. The total utility is usually assumed...

  3. Environmental surveillance master sampling schedule

    International Nuclear Information System (INIS)

    Bisping, L.E.

    1994-02-01

    This document contains the planned 1994 schedules for routine collection of samples for the Surface Environmental Surveillance Project (SESP), Drinking Water Project, and Ground-Water Surveillance Project. Samples are routinely collected for the SESP and analyzed to determine the quality of air, surface water, soil, sediment, wildlife, vegetation, foodstuffs, and farm products at Hanford Site and surrounding communities. The responsibility for monitoring the onsite drinking water falls outside the scope of the SESP. The Hanford Environmental Health Foundation is responsible for monitoring the nonradiological parameters as defined in the National Drinking Water Standards while PNL conducts the radiological monitoring of the onsite drinking water. PNL conducts the drinking water monitoring project concurrent with the SESP to promote efficiency and consistency, utilize the expertise developed over the years, and reduce costs associated with management, procedure development, data management, quality control and reporting. The ground-water sampling schedule identifies ground-water sampling events used by PNL for environmental surveillance of the Hanford Site

  4. Environmental surveillance master sampling schedule

    Energy Technology Data Exchange (ETDEWEB)

    Bisping, L.E.

    1994-02-01

    This document contains the planned 1994 schedules for routine collection of samples for the Surface Environmental Surveillance Project (SESP), Drinking Water Project, and Ground-Water Surveillance Project. Samples are routinely collected for the SESP and analyzed to determine the quality of air, surface water, soil, sediment, wildlife, vegetation, foodstuffs, and farm products at Hanford Site and surrounding communities. The responsibility for monitoring the onsite drinking water falls outside the scope of the SESP. The Hanford Environmental Health Foundation is responsible for monitoring the nonradiological parameters as defined in the National Drinking Water Standards while PNL conducts the radiological monitoring of the onsite drinking water. PNL conducts the drinking water monitoring project concurrent with the SESP to promote efficiency and consistency, utilize the expertise developed over the years, and reduce costs associated with management, procedure development, data management, quality control and reporting. The ground-water sampling schedule identifies ground-water sampling events used by PNL for environmental surveillance of the Hanford Site.

  5. Cbs (Contrastrain Based Schedulling Adalah Faktor Penentu Keberhasilan Perusahanan Printing

    Directory of Open Access Journals (Sweden)

    Hendra Achmadi

    2010-06-01

    Full Text Available In a highly competitive industry faces today ranging from small or home-based printing to using machine that can print offset a hundred thousand copies per hour. But, the increasing competition resulted in requiring a faster production time from order entry, print proff until the production process to delivery to customers. Often times in case of orders which will result in the concurrent PPIC will experience vertigo in the setting of production schedules which have concurrent delivery time. Often will end up with no receipt of orders due to difficulties in the production schedule, especially if the orders require the same offset machine and cylinder wear the same length, while the number of cylinders is limited. Therefore, the printing company should be able to do so in the conduct of a penetration timing of production can easily be simulated and implemented on the ground. CBS (Base Constraint scheduling is a technique to do the scheduling of production so that production can be carried out smoothly and quickly that fulfill the promise made to customers. In scheduling, there are several techniques that can be used are: FCFS (First Came First Serve, EDD (Earliest Date, and LCLS (Last Came Last Serve. So, it is required to be able to do way better scheduling to get results quickly in this fast changing schedules.

  6. Crane Scheduling for a Plate Storage

    DEFF Research Database (Denmark)

    Hansen, Jesper; Clausen, Jens

    2002-01-01

    Odense Steel Shipyard produces the worlds largest container ships. The first process of producing the steel ships is handling arrival and storage of steel plates until they are needed in production. This paper considers the problem of scheduling two cranes that carry out the movements of plates...... into, around and out of the storage. The system is required to create a daily schedule for the cranes, but also handle possible disruptions during the execution of the plan. The problem is solved with a Simulated Annealing algorithm....

  7. An improved sheep flock heredity algorithm for job shop scheduling and flow shop scheduling problems

    Directory of Open Access Journals (Sweden)

    Chandramouli Anandaraman

    2011-10-01

    Full Text Available Job Shop Scheduling Problem (JSSP and Flow Shop Scheduling Problem (FSSP are strong NP-complete combinatorial optimization problems among class of typical production scheduling problems. An improved Sheep Flock Heredity Algorithm (ISFHA is proposed in this paper to find a schedule of operations that can minimize makespan. In ISFHA, the pairwise mutation operation is replaced by a single point mutation process with a probabilistic property which guarantees the feasibility of the solutions in the local search domain. A Robust-Replace (R-R heuristic is introduced in place of chromosomal crossover to enhance the global search and to improve the convergence. The R-R heuristic is found to enhance the exploring potential of the algorithm and enrich the diversity of neighborhoods. Experimental results reveal the effectiveness of the proposed algorithm, whose optimization performance is markedly superior to that of genetic algorithms and is comparable to the best results reported in the literature.

  8. Concept of Indoor 3D-Route UAV Scheduling System

    DEFF Research Database (Denmark)

    Khosiawan, Yohanes; Nielsen, Izabela Ewa; Do, Ngoc Ang Dung

    2016-01-01

    environment. On top of that, the multi-source productive best-first-search concept also supports efficient real-time scheduling in response to uncertain events. Without human intervention, the proposed work provides an automatic scheduling system for UAV routing problem in 3D indoor environment....

  9. 50 CFR 260.70 - Schedule of fees.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Schedule of fees. 260.70 Section 260.70... Products for Human Consumption Fees and Charges § 260.70 Schedule of fees. (a) Unless otherwise provided in a written agreement between the applicant and the Secretary, the fees to be charged and collected...

  10. NRC comprehensive records disposition schedule

    International Nuclear Information System (INIS)

    1982-07-01

    Effective January 1, 1982, NRC will institute records retention and disposal practices in accordance with the approved Comprehensive Records Disposition Schedule (CRDS). CRDS is comprised of NRC Schedules (NRCS) 1 to 4 which apply to the agency's program or substantive records and General Records Schedules (GRS) 1 to 22 which apply to housekeeping or facilitative records. The schedules are assembled functionally/organizationally to facilitate their use. Preceding the records descriptions and disposition instructions for both NRCS and GRS, there are brief statements on the organizational units which accumulate the records in each functional area, and other information regarding the schedules' applicability

  11. Physical activity during video capsule endoscopy correlates with shorter bowel transit time.

    Science.gov (United States)

    Stanich, Peter P; Peck, Joshua; Murphy, Christopher; Porter, Kyle M; Meyer, Marty M

    2017-09-01

     Video capsule endoscopy (VCE) is limited by reliance on bowel motility for propulsion, and lack of physical activity has been proposed as a cause of incomplete studies. Our aim was to prospectively investigate the association between physical activity and VCE bowel transit.  Ambulatory outpatients receiving VCE were eligible for the study. A pedometer was attached at the time of VCE ingestion and step count was recorded at the end of the procedure. VCE completion was assessed by logistic regression models, which included step count (500 steps as one unit). Total transit time was analyzed by Cox proportional hazards models. The hazard ratios (HR) with 95 % confidence interval (CI) indicated the "hazard" of completion, such that HRs > 1 indicated a reduced transit time.  A total of 100 patients were included. VCE was completed in 93 patients (93 %). The median step count was 2782 steps. Step count was not significantly associated with VCE completion (odds ratio 1.45, 95 %CI 0.84, 2.49). Pedometer step count was significantly associated with shorter total, gastric, and small-bowel transit times (HR 1.09, 95 %CI 1.03, 1.16; HR 1.05, 95 %CI 1.00, 1.11; HR 1.07, 95 %CI 1.01, 1.14, respectively). Higher body mass index (BMI) was significantly associated with VCE completion (HR 1.87, 95 %CI 1.18, 2.97) and shorter bowel transit times (HR 1.05, 95 %CI 1.02, 1.08).  Increased physical activity during outpatient VCE was associated with shorter bowel transit times but not with study completion. In addition, BMI was a previously unreported clinical characteristic associated with VCE completion and should be included as a variable of interest in future studies.

  12. The impact of system level factors on treatment timeliness: utilizing the Toyota Production System to implement direct intake scheduling in a semi-rural community mental health clinic.

    Science.gov (United States)

    Weaver, Addie; Greeno, Catherine G; Goughler, Donald H; Yarzebinski, Kathleen; Zimmerman, Tina; Anderson, Carol

    2013-07-01

    This study examined the effect of using the Toyota Production System (TPS) to change intake procedures on treatment timeliness within a semi-rural community mental health clinic. One hundred randomly selected cases opened the year before the change and 100 randomly selected cases opened the year after the change were reviewed. An analysis of covariance demonstrated that changing intake procedures significantly decreased the number of days consumers waited for appointments (F(1,160) = 4.9; p = .03) from an average of 11 to 8 days. The pattern of difference on treatment timeliness was significantly different between adult and child programs (F(1,160) = 4.2; p = .04), with children waiting an average of 4 days longer than adults for appointments. Findings suggest that small system level changes may elicit important changes and that TPS offers a valuable model to improve processes within community mental health settings. Results also indicate that different factors drive adult and children's treatment timeliness.

  13. Reemission spectra and inelastic processes at interaction of attosecond and shorter duration electromagnetic pulses with atoms

    International Nuclear Information System (INIS)

    Makarov, D.N.; Matveev, V.I.

    2017-01-01

    Inelastic processes and the reemission of attosecond and shorter electromagnetic pulses by atoms have been considered within the analytical solution of the Schrödinger equation in the sudden perturbation approximation. A method of calculations with the exact inclusion of spatial inhomogeneity of the field of an ultrashort pulse and the momenta of photons in the reemission processes has been developed. The probabilities of inelastic processes and spectra of reemission of ultrashort electromagnetic pulses by one- and many-electron atoms have been calculated. The results have been presented in the form of analytical formulas.

  14. Practical quantum appointment scheduling

    Science.gov (United States)

    Touchette, Dave; Lovitz, Benjamin; Lütkenhaus, Norbert

    2018-04-01

    We propose a protocol based on coherent states and linear optics operations for solving the appointment-scheduling problem. Our main protocol leaks strictly less information about each party's input than the optimal classical protocol, even when considering experimental errors. Along with the ability to generate constant-amplitude coherent states over two modes, this protocol requires the ability to transfer these modes back-and-forth between the two parties multiple times with very low losses. The implementation requirements are thus still challenging. Along the way, we develop tools to study quantum information cost of interactive protocols in the finite regime.

  15. Scheduling theory, algorithms, and systems

    CERN Document Server

    Pinedo, Michael L

    2016-01-01

    This new edition of the well-established text Scheduling: Theory, Algorithms, and Systems provides an up-to-date coverage of important theoretical models in the scheduling literature as well as important scheduling problems that appear in the real world. The accompanying website includes supplementary material in the form of slide-shows from industry as well as movies that show actual implementations of scheduling systems. The main structure of the book, as per previous editions, consists of three parts. The first part focuses on deterministic scheduling and the related combinatorial problems. The second part covers probabilistic scheduling models; in this part it is assumed that processing times and other problem data are random and not known in advance. The third part deals with scheduling in practice; it covers heuristics that are popular with practitioners and discusses system design and implementation issues. All three parts of this new edition have been revamped, streamlined, and extended. The reference...

  16. Economic Benefit from Progressive Integration of Scheduling and Control for Continuous Chemical Processes

    Directory of Open Access Journals (Sweden)

    Logan D. R. Beal

    2017-12-01

    Full Text Available Performance of integrated production scheduling and advanced process control with disturbances is summarized and reviewed with four progressive stages of scheduling and control integration and responsiveness to disturbances: open-loop segregated scheduling and control, closed-loop segregated scheduling and control, open-loop scheduling with consideration of process dynamics, and closed-loop integrated scheduling and control responsive to process disturbances and market fluctuations. Progressive economic benefit from dynamic rescheduling and integrating scheduling and control is shown on a continuously stirred tank reactor (CSTR benchmark application in closed-loop simulations over 24 h. A fixed horizon integrated scheduling and control formulation for multi-product, continuous chemical processes is utilized, in which nonlinear model predictive control (NMPC and continuous-time scheduling are combined.

  17. The Impact of System Level Factors on Treatment Timeliness: Utilizing the Toyota Production System to Implement Direct Intake Scheduling in a Semi-Rural Community Mental Health Clinic

    Science.gov (United States)

    Weaver, A.; Greeno, C.G.; Goughler, D.H.; Yarzebinski, K.; Zimmerman, T.; Anderson, C.

    2013-01-01

    This study examined the effect of using the Toyota Production System (TPS) to change intake procedures on treatment timeliness within a semi-rural community mental health clinic. One hundred randomly selected cases opened the year before the change and one hundred randomly selected cases opened the year after the change were reviewed. An analysis of covariance (ANCOVA) demonstrated that changing intake procedures significantly decreased the number of days consumers waited for appointments (F(1,160)=4.9; p=.03) from an average of 11 days to 8 days. The pattern of difference on treatment timeliness was significantly different between adult and child programs (F(1,160)=4.2; p=.04), with children waiting an average of 4 days longer than adults for appointments. Findings suggest that small system level changes may elicit important changes and that TPS offers a valuable model to improve processes within community mental health settings. Results also indicate that different factors drive adult and children’s treatment timeliness. PMID:23576137

  18. Shorter preschool, leukocyte telomere length is associated with obesity at age 9 in Latino children.

    Science.gov (United States)

    Kjaer, T W; Faurholt-Jepsen, D; Mehta, K M; Christensen, V B; Epel, E; Lin, J; Blackburn, E; Wojcicki, J M

    2018-04-01

    The aim of this study was to determine the potential role of leukocyte telomere length as a biomarker for development of childhood obesity in a low-income Latino population. A birth cohort of Latino children (N = 201) in San Francisco (recruited May 2006-May 2007) was followed until age 9 and assessed annually for obesity and dietary intake. Leukocyte telomere length was measured at 4 and 5 years (n = 102) and assessed as a predictor for obesity at age 9, adjusting for known risk factors. Furthermore, leukocyte telomere length at age 4 and 5 was evaluated as a possible mediator of the relationship between excessive sugar-sweetened beverage consumption and obesity at age 9. Shorter leukocyte telomere length in preschoolers was associated with obesity at age 9 (adjusted odds ratio 0.35, 95% confidence interval 0.13-0.94) after adjustment for known risk factors. Telomere length mediated 11% of the relationship between excessive sugar-sweetened beverage consumption and obesity. Shorter leukocyte telomere length may be an indicator of future obesity risk in high-risk populations as it is particularly sensitive to damage from oxidative stress exposure, including those from sugar-sweetened beverages. © 2017 World Obesity Federation.

  19. Applicability of the shorter ‘Bangladesh regimen’ in high multidrug-resistant tuberculosis settings

    Directory of Open Access Journals (Sweden)

    Giovanni Sotgiu

    2017-03-01

    Full Text Available In spite of the recent introduction of two new drugs (delamanid and bedaquiline and a few repurposed compounds to treat multidrug-resistant and extensively drug-resistant tuberculosis (MDR- and XDR-TB, clinicians are facing increasing problems in designing effective regimens in severe cases. Recently a 9 to 12-month regimen (known as the ‘Bangladesh regimen’ proved to be effective in treating MDR-TB cases. It included an initial phase of 4 to 6 months of kanamycin, moxifloxacin, prothionamide, clofazimine, pyrazinamide, high-dose isoniazid, and ethambutol, followed by 5 months of moxifloxacin, clofazimine, pyrazinamide, and ethambutol. However, recent evidence from Europe and Latin America identified prevalences of resistance to the first-line drugs in this regimen (ethambutol and pyrazinamide exceeding 60%, and of prothionamide exceeding 50%. Furthermore, the proportions of resistance to the two most important pillars of the regimen – quinolones and kanamycin – were higher than 40%. Overall, only 14 out of 348 adult patients (4.0% were susceptible to all of the drugs composing the regimen, and were therefore potentially suitable for the ‘shorter regimen’. A shorter, cheaper, and well-tolerated MDR-TB regimen is likely to impact the number of patients treated and improve adherence if prescribed to the right patients through the systematic use of rapid MTBDRsl testing.

  20. Representativeness of shorter measurement sessions in long-term indoor air monitoring.

    Science.gov (United States)

    Maciejewska, M; Szczurek, A

    2015-02-01

    Indoor air quality (IAQ) considerably influences health, comfort and the overall performance of people who spend most of their lives in confined spaces. For this reason, there is a strong need to develop methods for IAQ assessment. The fundamental issue in the quantitative determination of IAQ is the duration of measurements. Its inadequate choice may result in providing incorrect information and this potentially leads to wrong conclusions. The most complete information may be acquired through long-term monitoring. However it is typically perceived as impractical due to time and cost load. The aim of this study was to determine whether long-term monitoring can be adequately represented by a shorter measurement session. There were considered three measurable quantities: temperature, relative humidity and carbon dioxide concentration. They are commonly recognized as indicatives for IAQ and may be readily monitored. Scaled Kullback-Leibler divergence, also called relative entropy, was applied as a measure of data representativeness. We considered long-term monitoring in a range from 1 to 9 months. Based on our work, the representative data on CO2 concentration may be acquired while performing measurements during 20% of time dedicated to long-term monitoring. In the case of temperature and relative humidity the respective time demand was 50% of long-term monitoring. From our results, in indoor air monitoring strategies, there could be considered shorter measurement sessions, while still collecting data which are representative for long-term monitoring.

  1. Are Shorter Versions of the Positive and Negative Syndrome Scale (PANSS) Doable? A Critical Review.

    Science.gov (United States)

    Lindenmayer, Jean-Pierre

    2017-12-01

    The Positive and Negative Syndrome Scale (PANSS) is a well-established assessment tool for measuring symptom severity in schizophrenia. Researchers and clinicians have been interested in the development of a short version of the PANSS that could reduce the burden of its administration for patients and raters. The author presents a comprehensive overview of existing brief PANSS measures, including their strengths and limitations, and discusses some possible next steps. There are two available scales that offer a reduced number of original PANSS items: PANSS-14 and PANSS-19; and two shorter versions that include six items: Brief PANSS and PANSS-6. The PANSS-6 has been tested quite extensively in established trials and appears to demonstrate high sensitivity to change and an established cut off definition for remission. Prospective testing in new antipsychotic treatment trials is still required for these shorter versions of PANSS. In addition, they need to be supplemented with interview guides, as well as provide conversion formulas to translate total scores from the short PANSS versions to the PANSS-30. Both short versions of the PANSS are essentially designed to evaluate response to antipsychotic treatment. Future PANSS scale development needs to address specific measurement of treatment-responsive positive symptoms by including treatment-sensitive items, as well as illness-phase specific PANSS tools.

  2. Perceptions of randomized security schedules.

    Science.gov (United States)

    Scurich, Nicholas; John, Richard S

    2014-04-01

    Security of infrastructure is a major concern. Traditional security schedules are unable to provide omnipresent coverage; consequently, adversaries can exploit predictable vulnerabilities to their advantage. Randomized security schedules, which randomly deploy security measures, overcome these limitations, but public perceptions of such schedules have not been examined. In this experiment, participants were asked to make a choice between attending a venue that employed a traditional (i.e., search everyone) or a random (i.e., a probability of being searched) security schedule. The absolute probability of detecting contraband was manipulated (i.e., 1/10, 1/4, 1/2) but equivalent between the two schedule types. In general, participants were indifferent to either security schedule, regardless of the probability of detection. The randomized schedule was deemed more convenient, but the traditional schedule was considered fairer and safer. There were no differences between traditional and random schedule in terms of perceived effectiveness or deterrence. Policy implications for the implementation and utilization of randomized schedules are discussed. © 2013 Society for Risk Analysis.

  3. Rostering and Task Scheduling

    DEFF Research Database (Denmark)

    Dohn, Anders Høeg

    . The rostering process is non-trivial and especially when service is required around the clock, rostering may involve considerable effort from a designated planner. Therefore, in order to minimize costs and overstaffing, to maximize the utilization of available staff, and to ensure a high level of satisfaction...... as possible to the available staff, while respecting various requirements and rules and while including possible transportation time between tasks. This thesis presents a number of industrial applications in rostering and task scheduling. The applications exist within various contexts in health care....... Mathematical and logic-based models are presented for the problems considered. Novel components are added to existing models and the modeling decisions are justified. In one case, the model is solved by a simple, but efficient greedy construction heuristic. In the remaining cases, column generation is applied...

  4. Scheduling the powering tests

    CERN Document Server

    Barbero-Soto, E; Casas-Lino, M P; Fernandez-Robles, C; Foraz, K; Pojer, M; Saban, R; Schmidt, R; Solfaroli-Camillocci, M; Vergara-Fernandez, A

    2008-01-01

    The Large Hadron Collider is now entering in its final phase before receiving beam, and the activities at CERN between 2007 and 2008 have shifted from installation work to the commissioning of the technical systems ("hardware commissioning"). Due to the unprecedented complexity of this machine, all the systems are or will be tested as far as possible before the cool-down starts. Systems are firstly tested individually before being globally tested together. The architecture of LHC, which is partitioned into eight cryogenically and electrically independent sectors, allows the commissioning on a sector by sector basis. When a sector reaches nominal cryogenic conditions, commissioning of the magnet powering system to nominal current for all magnets can be performed. This paper briefly describes the different activities to be performed during the powering tests of the superconducting magnet system and presents the scheduling issues raised by co-activities as well as the management of resources.

  5. Towards shorter wavelength x-ray lasers using a high power, short pulse pump laser

    International Nuclear Information System (INIS)

    Tighe, W.; Krushelnick, K.; Valeo, E.; Suckewer, S.

    1991-05-01

    A near-terawatt, KrF* laser system, focussable to power densities >10 18 W/cm 2 has been constructed for use as a pump laser in various schemes aimed at the development of x-ray lasing below 5nm. The laser system along with output characteristics such as the pulse duration, the focal spot size, and the percentage of amplified spontaneous emission (ASE) emitted along with the laser pulse will be presented. Schemes intended to lead to shorter wavelength x-ray emission will be described. The resultant requirements on the pump laser characteristics and the target design will be outlined. Results from recent solid target experiments and two-laser experiments, showing the interaction of a high-power, short pulse laser with a preformed plasma, will be presented. 13 refs., 5 figs

  6. Shorter epilepsy duration is associated with better seizure outcome in temporal lobe epilepsy surgery

    Directory of Open Access Journals (Sweden)

    Lucas Crociati Meguins

    2015-03-01

    Full Text Available Objective To investigate the influence of patient’s age and seizure onset on surgical outcome of temporal lobe epilepsy (TLE. Method A retrospective observational investigation performed from a cohort of patients from 2000 to 2012. Results A total of 229 patients were included. One-hundred and eleven of 179 patients (62% were classified as Engel I in the group with < 50 years old, whereas 33 of 50 (66% in the group with ≥ 50 years old group (p = 0.82. From those Engel I, 88 (61% reported epilepsy duration inferior to 10 years and 56 (39% superior to 10 years (p < 0.01. From the total of patients not seizure free, 36 (42% reported epilepsy duration inferior to 10 years and 49 (58% superior to 10 years (p < 0.01. Conclusion Patients with shorter duration of epilepsy before surgery had better postoperative seizure control than patients with longer duration of seizures.

  7. Association of mutations in the hemochromatosis gene with shorter life expectancy

    DEFF Research Database (Denmark)

    Bathum, L; Christiansen, L; Nybo, H

    2001-01-01

    BACKGROUND: To investigate whether the frequency of carriers of mutations in the HFE gene associated with hereditary hemochromatosis diminishes with age as an indication that HFE mutations are associated with increased mortality. It is of value in the debate concerning screening for hereditary...... hemochromatosis to determine the significance of heterozygosity. METHODS: Genotyping for mutations in exons 2 and 4 of the HFE gene using denaturing gradient gel electrophoresis in 1784 participants aged 45 to 100 years from 4 population-based studies: all 183 centenarians from the Danish Centenarian Study, 601...... in the distribution of mutations in exon 2 in the different age groups. CONCLUSIONS: In a high-carrier frequency population like Denmark, mutations in HFE show an age-related reduction in the frequency of heterozygotes for C282Y, which suggests that carrier status is associated with shorter life expectancy....

  8. Shorter Decentralized Attribute-Based Encryption via Extended Dual System Groups

    Directory of Open Access Journals (Sweden)

    Jie Zhang

    2017-01-01

    Full Text Available Decentralized attribute-based encryption (ABE is a special form of multiauthority ABE systems, in which no central authority and global coordination are required other than creating the common reference parameters. In this paper, we propose a new decentralized ABE in prime-order groups by using extended dual system groups. We formulate some assumptions used to prove the security of our scheme. Our proposed scheme is fully secure under the standard k-Lin assumption in random oracle model and can support any monotone access structures. Compared with existing fully secure decentralized ABE systems, our construction has shorter ciphertexts and secret keys. Moreover, fast decryption is achieved in our system, in which ciphertexts can be decrypted with a constant number of pairings.

  9. Shorter preschool, leukocyte telomere length is associated with obesity at age 9 in Latino children

    DEFF Research Database (Denmark)

    Kjaer, Thora Wesenberg; Faurholt-Jepsen, D; Mehta, K M

    2018-01-01

    The aim of this study was to determine the potential role of leukocyte telomere length as a biomarker for development of childhood obesity in a low-income Latino population. A birth cohort of Latino children (N = 201) in San Francisco (recruited May 2006-May 2007) was followed until age 9...... and assessed annually for obesity and dietary intake. Leukocyte telomere length was measured at 4 and 5 years (n = 102) and assessed as a predictor for obesity at age 9, adjusting for known risk factors. Furthermore, leukocyte telomere length at age 4 and 5 was evaluated as a possible mediator...... of the relationship between excessive sugar-sweetened beverage consumption and obesity at age 9. Shorter leukocyte telomere length in preschoolers was associated with obesity at age 9 (adjusted odds ratio 0.35, 95% confidence interval 0.13-0.94) after adjustment for known risk factors. Telomere length mediated 11...

  10. Sport Tournament Automated Scheduling System

    OpenAIRE

    Raof R. A. A; Sudin S.; Mahrom N.; Rosli A. N. C

    2018-01-01

    The organizer of sport events often facing problems such as wrong calculations of marks and scores, as well as difficult to create a good and reliable schedule. Most of the time, the issues about the level of integrity of committee members and also issues about errors made by human came into the picture. Therefore, the development of sport tournament automated scheduling system is proposed. The system will be able to automatically generate the tournament schedule as well as automatically calc...

  11. Hereditary angioedema attacks resolve faster and are shorter after early icatibant treatment.

    Directory of Open Access Journals (Sweden)

    Marcus Maurer

    Full Text Available BACKGROUND: Attacks of hereditary angioedema (HAE are unpredictable and, if affecting the upper airway, can be lethal. Icatibant is used for physician- or patient self-administered symptomatic treatment of HAE attacks in adults. Its mode of action includes disruption of the bradykinin pathway via blockade of the bradykinin B(2 receptor. Early treatment is believed to shorten attack duration and prevent severe outcomes; however, evidence to support these benefits is lacking. OBJECTIVE: To examine the impact of timing of icatibant administration on the duration and resolution of HAE type I and II attacks. METHODS: The Icatibant Outcome Survey is an international, prospective, observational study for patients treated with icatibant. Data on timings and outcomes of icatibant treatment for HAE attacks were collected between July 2009-February 2012. A mixed-model of repeated measures was performed for 426 attacks in 136 HAE type I and II patients. RESULTS: Attack duration was significantly shorter in patients treated <1 hour of attack onset compared with those treated ≥ 1 hour (6.1 hours versus 16.8 hours [p<0.001]. Similar significant effects were observed for <2 hours versus ≥ 2 hours (7.2 hours versus 20.2 hours [p<0.001] and <5 hours versus ≥ 5 hours (8.0 hours versus 23.5 hours [p<0.001]. Treatment within 1 hour of attack onset also significantly reduced time to attack resolution (5.8 hours versus 8.8 hours [p<0.05]. Self-administrators were more likely to treat early and experience shorter attacks than those treated by a healthcare professional. CONCLUSION: Early blockade of the bradykinin B(2 receptor with icatibant, particularly within the first hour of attack onset, significantly reduced attack duration and time to attack resolution.

  12. Smoking Topography among Korean Smokers: Intensive Smoking Behavior with Larger Puff Volume and Shorter Interpuff Interval.

    Science.gov (United States)

    Kim, Sungroul; Yu, Sol

    2018-05-18

    The difference of smoker's topography has been found to be a function many factors, including sex, personality, nicotine yield, cigarette type (i.e., flavored versus non-flavored) and ethnicity. We evaluated the puffing behaviors of Korean smokers and its association with smoking-related biomarker levels. A sample of 300 participants was randomly recruited from metropolitan areas in South Korea. Topography measures during a 24-hour period were obtained using a CReSS pocket device. Korean male smokers smoked two puffs less per cigarette compared to female smokers (15.0 (13.0⁻19.0) vs. 17.5 (15.0⁻21.0) as the median (Interquartile range)), but had a significantly larger puff volume (62.7 (52.7⁻75.5) mL vs. 53.5 (42.0⁻64.2) mL); p = 0.012). The interpuff interval was similar between men and women (8.9 (6.5⁻11.2) s vs. 8.3 (6.2⁻11.0) s; p = 0.122) but much shorter than other study results. A dose-response association ( p = 0.0011) was observed between daily total puff volumes and urinary cotinine concentrations, after controlling for sex, age, household income level and nicotine addiction level. An understanding of the difference of topography measures, particularly the larger puff volume and shorter interpuff interval of Korean smokers, may help to overcome a potential underestimation of internal doses of hazardous byproducts of smoking.

  13. ATM/RB1 mutations predict shorter overall survival in urothelial cancer.

    Science.gov (United States)

    Yin, Ming; Grivas, Petros; Emamekhoo, Hamid; Mendiratta, Prateek; Ali, Siraj; Hsu, JoAnn; Vasekar, Monali; Drabick, Joseph J; Pal, Sumanta; Joshi, Monika

    2018-03-30

    Mutations of DNA repair genes, e.g. ATM/RB1 , are frequently found in urothelial cancer (UC) and have been associated with better response to cisplatin-based chemotherapy. Further external validation of the prognostic value of ATM/RB1 mutations in UC can inform clinical decision making and trial designs. In the discovery dataset, ATM/RB1 mutations were present in 24% of patients and were associated with shorter OS (adjusted HR 2.67, 95% CI, 1.45-4.92, p = 0.002). There was a higher mutation load in patients carrying ATM/RB1 mutations (median mutation load: 6.7 versus 5.5 per Mb, p = 0.072). In the validation dataset, ATM/RB1 mutations were present in 22.2% of patients and were non-significantly associated with shorter OS (adjusted HR 1.87, 95% CI, 0.97-3.59, p = 0.06) and higher mutation load (median mutation load: 8.1 versus 7.2 per Mb, p = 0.126). Exome sequencing data of 130 bladder UC patients from The Cancer Genome Atlas (TCGA) dataset were analyzed as a discovery cohort to determine the prognostic value of ATM/RB1 mutations. Results were validated in an independent cohort of 81 advanced UC patients. Cox proportional hazard regression analysis was performed to calculate the hazard ratio (HR) and 95% confidence interval (CI) to compare overall survival (OS). ATM/RB1 mutations may be a biomarker of poor prognosis in unselected UC patients and may correlate with higher mutational load. Further studies are required to determine factors that can further stratify prognosis and evaluate predictive role of ATM/RB1 mutation status to immunotherapy and platinum-based chemotherapy.

  14. Marital disruption is associated with shorter salivary telomere length in a probability sample of older adults.

    Science.gov (United States)

    Whisman, Mark A; Robustelli, Briana L; Sbarra, David A

    2016-05-01

    Marital disruption (i.e., marital separation, divorce) is associated with a wide range of poor mental and physical health outcomes, including increased risk for all-cause mortality. One biological intermediary that may help explain the association between marital disruption and poor health is accelerated cellular aging. This study examines the association between marital disruption and salivary telomere length in a United States probability sample of adults ≥50 years of age. Participants were 3526 individuals who participated in the 2008 wave of the Health and Retirement Study. Telomere length assays were performed using quantitative real-time polymerase chain reaction (qPCR) on DNA extracted from saliva samples. Health and lifestyle factors, traumatic and stressful life events, and neuroticism were assessed via self-report. Linear regression analyses were conducted to examine the associations between predictor variables and salivary telomere length. Based on their marital status data in the 2006 wave, people who were separated or divorced had shorter salivary telomeres than people who were continuously married or had never been married, and the association between marital disruption and salivary telomere length was not moderated by gender or neuroticism. Furthermore, the association between marital disruption and salivary telomere length remained statistically significant after adjusting for demographic and socioeconomic variables, neuroticism, cigarette use, body mass, traumatic life events, and other stressful life events. Additionally, results revealed that currently married adults with a history of divorce evidenced shorter salivary telomeres than people who were continuously married or never married. Accelerated cellular aging, as indexed by telomere shortening, may be one pathway through which marital disruption is associated with morbidity and mortality. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Designing an advanced available-to-promise mechanism compatible with the make-to-forecast production systems through integrating inventory allocation and job shop scheduling with due dates and weighted earliness/tardiness cost

    Directory of Open Access Journals (Sweden)

    Masoud Rabbani

    2016-06-01

    Full Text Available In the competitive business world, applying a reliable and powerful mechanism to support decision makers in manufacturing companies and helping them save time by considering varieties of effective factors is an inevitable issue. Advanced Available-to-Promise is a perfect tool to design and perform such a mechanism. In this study, this mechanism which is compatible with the Make-to-Forecast production systems is presented. The ability to distinguish between batch mode and real-time mode advanced available-to-promise is one of the unique superiorities of the proposed model. We also try to strengthen this mechanism by integrating the inventory allocation and job shop scheduling by considering due dates and weighted earliness/tardiness cost that leads to more precise decisions. A mixed integer programming (MIP model and a heuristic algorithm according to its disability to solve large size problems are presented. The designed experiments and the obtained results have proved the efficiency of the proposed heuristic method.

  16. NRC comprehensive records disposition schedule

    International Nuclear Information System (INIS)

    1992-03-01

    Title 44 United States Code, ''Public Printing and Documents,'' regulations cited in the General Services Administration's (GSA) ''Federal Information Resources Management Regulations'' (FIRMR), Part 201-9, ''Creation, Maintenance, and Use of Records,'' and regulation issued by the National Archives and Records Administration (NARA) in 36 CFR Chapter XII, Subchapter B, ''Records Management,'' require each agency to prepare and issue a comprehensive records disposition schedule that contains the NARA approved records disposition schedules for records unique to the agency and contains the NARA's General Records Schedules for records common to several or all agencies. The approved records disposition schedules specify the appropriate duration of retention and the final disposition for records created or maintained by the NRC. NUREG-0910, Rev. 2, contains ''NRC's Comprehensive Records Disposition Schedule,'' and the original authorized approved citation numbers issued by NARA. Rev. 2 totally reorganizes the records schedules from a functional arrangement to an arrangement by the host office. A subject index and a conversion table have also been developed for the NRC schedules to allow staff to identify the new schedule numbers easily and to improve their ability to locate applicable schedules

  17. Schedules of Controlled Substances: Temporary Placement of 4-Fluoroisobutyryl Fentanyl into Schedule I. Temporary scheduling order.

    Science.gov (United States)

    2017-05-03

    The Administrator of the Drug Enforcement Administration is issuing this temporary scheduling order to schedule the synthetic opioid, N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide (4-fluoroisobutyryl fentanyl or para-fluoroisobutyryl fentanyl), and its isomers, esters, ethers, salts and salts of isomers, esters, and ethers, into schedule I pursuant to the temporary scheduling provisions of the Controlled Substances Act. This action is based on a finding by the Administrator that the placement of 4-fluoroisobutyryl fentanyl into schedule I of the Controlled Substances Act is necessary to avoid an imminent hazard to the public safety. As a result of this order, the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances will be imposed on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis, or possess), or propose to handle, 4-fluoroisobutyryl fentanyl.

  18. A Work Schedule to Increase Productivity.

    Science.gov (United States)

    Atwood, Caleb S.

    1979-01-01

    Outlines a technique for making a tight economy and energy shortages more palatable by supplementing employee wage increases with benefits such as alternative three and four day "weekends" without loss of regular pay and by enabling business to increase profits. (Author/IRT)

  19. Cellular Scheduling of Batch Production Using | Onyeagoro ...

    African Journals Online (AJOL)

    Nigerian Journal of Technology. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 5, No 1 (1981) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should ...

  20. Prioritizing sleep for healthy work schedules

    OpenAIRE

    Takahashi Masaya

    2012-01-01

    Abstract Good sleep is advantageous to the quality of life. Sleep-related benefits are particularly helpful for the working class, since poor or inadequate amounts of sleep degrade work productivity and overall health. This review paper explores the essential role of sleep in healthy work schedules and primarily focuses on the timing of sleep in relation to the work period (that is, before, during and after work). Data from laboratory, field and modeling studies indicate that consistent amoun...

  1. Direct block scheduling technology: Analysis of Avidity

    Directory of Open Access Journals (Sweden)

    Felipe Ribeiro Souza

    Full Text Available Abstract This study is focused on Direct Block Scheduling testing (Direct Multi-Period Scheduling methodology which schedules mine production considering the correct discount factor of each mining block, resulting in the final pit. Each block is analyzed individually in order to define the best target period. This methodology presents an improvement of the classical methodology derived from Lerchs-Grossmann's initial proposition improved by Whittle. This paper presents the differences between these methodologies, specially focused on the algorithms' avidity. Avidity is classically defined by the voracious search algorithms, whereupon some of the most famous greedy algorithms are Branch and Bound, Brutal Force and Randomized. Strategies based on heuristics can accentuate the voracity of the optimizer system. The applied algorithm use simulated annealing combined with Tabu Search. The most avid algorithm can select the most profitable blocks in early periods, leading to higher present value in the first periods of mine operation. The application of discount factors to blocks on the Lerchs-Grossmann's final pit has an accentuated effect with time, and this effect may make blocks scheduled for the end of the mine life unfeasible, representing a trend to a decrease in reported reserves.

  2. Combined Noncyclic Scheduling and Advanced Control for Continuous Chemical Processes

    Directory of Open Access Journals (Sweden)

    Damon Petersen

    2017-12-01

    Full Text Available A novel formulation for combined scheduling and control of multi-product, continuous chemical processes is introduced in which nonlinear model predictive control (NMPC and noncyclic continuous-time scheduling are efficiently combined. A decomposition into nonlinear programming (NLP dynamic optimization problems and mixed-integer linear programming (MILP problems, without iterative alternation, allows for computationally light solution. An iterative method is introduced to determine the number of production slots for a noncyclic schedule during a prediction horizon. A filter method is introduced to reduce the number of MILP problems required. The formulation’s closed-loop performance with both process disturbances and updated market conditions is demonstrated through multiple scenarios on a benchmark continuously stirred tank reactor (CSTR application with fluctuations in market demand and price for multiple products. Economic performance surpasses cyclic scheduling in all scenarios presented. Computational performance is sufficiently light to enable online operation in a dual-loop feedback structure.

  3. Practical principles in appointment scheduling

    NARCIS (Netherlands)

    Kuiper, A.; Mandjes, M.

    2015-01-01

    Appointment schedules aim at achieving a proper balance between the conflicting interests of the service provider and her clients: a primary objective of the service provider is to fully utilize her available time, whereas clients want to avoid excessive waiting times. Setting up schedules that

  4. Nontraditional work schedules for pharmacists.

    Science.gov (United States)

    Mahaney, Lynnae; Sanborn, Michael; Alexander, Emily

    2008-11-15

    Nontraditional work schedules for pharmacists at three institutions are described. The demand for pharmacists and health care in general continues to increase, yet significant material changes are occurring in the pharmacy work force. These changing demographics, coupled with historical vacancy rates and turnover trends for pharmacy staff, require an increased emphasis on workplace changes that can improve staff recruitment and retention. At William S. Middleton Memorial Veterans Affairs Hospital in Madison, Wisconsin, creative pharmacist work schedules and roles are now mainstays to the recruitment and retention of staff. The major challenge that such scheduling presents is the 8 hours needed to prepare a six-week schedule. Baylor Medical Center at Grapevine in Dallas, Texas, has a total of 45 pharmacy employees, and slightly less than half of the 24.5 full-time-equivalent staff work full-time, with most preferring to work one, two, or three days per week. As long as the coverage needs of the facility are met, Envision Telepharmacy in Alpine, Texas, allows almost any scheduling arrangement preferred by individual pharmacists or the pharmacist group covering the facility. Staffing involves a great variety of shift lengths and intervals, with shifts ranging from 2 to 10 hours. Pharmacy leaders must be increasingly aware of opportunities to provide staff with unique scheduling and operational enhancements that can provide for a better work-life balance. Compressed workweeks, job-sharing, and team scheduling were the most common types of alternative work schedules implemented at three different institutions.

  5. Modeling the Cray memory scheduler

    Energy Technology Data Exchange (ETDEWEB)

    Wickham, K.L.; Litteer, G.L.

    1992-04-01

    This report documents the results of a project to evaluate low cost modeling and simulation tools when applied to modeling the Cray memory scheduler. The specific tool used is described and the basics of the memory scheduler are covered. Results of simulations using the model are discussed and a favorable recommendation is made to make more use of this inexpensive technology.

  6. Flexible Work Schedules. ERIC Digest.

    Science.gov (United States)

    Kerka, Sandra

    Flexible work schedules are one response to changes in the composition of the work force, new life-styles, and changes in work attitudes. Types of alternative work schedules are part-time and temporary employment, job sharing, and flextime. Part-time workers are a diverse group--women, the very young, and older near-retirees. Although part-time…

  7. Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer's disease and progressive supranuclear palsy brains.

    Science.gov (United States)

    Huin, Vincent; Buée, Luc; Behal, Hélène; Labreuche, Julien; Sablonnière, Bernard; Dhaenens, Claire-Marie

    2017-10-03

    Alternative promoter usage is an important mechanism for transcriptome diversity and the regulation of gene expression. Indeed, this alternative usage may influence tissue/subcellular specificity, protein translation and function of the proteins. The existence of an alternative promoter for MAPT gene was considered for a long time to explain differential tissue specificity and differential response to transcription and growth factors between mRNA transcripts. The alternative promoter usage could explain partly the different tau proteins expression patterns observed in tauopathies. Here, we report on our discovery of a functional alternative promoter for MAPT, located upstream of the gene's second exon (exon 1). By analyzing genome databases and brain tissue from control individuals and patients with Alzheimer's disease or progressive supranuclear palsy, we identified novel shorter transcripts derived from this alternative promoter. These transcripts are increased in patients' brain tissue as assessed by 5'RACE-PCR and qPCR. We suggest that these new MAPT isoforms can be translated into normal or amino-terminal-truncated tau proteins. We further suggest that activation of MAPT's alternative promoter under pathological conditions leads to the production of truncated proteins, changes in protein localization and function, and thus neurodegeneration.

  8. Minimally invasive oesophagectomy more expensive than open despite shorter length of stay.

    Science.gov (United States)

    Dhamija, Anish; Dhamija, Ankit; Hancock, Jacquelyn; McCloskey, Barbara; Kim, Anthony W; Detterbeck, Frank C; Boffa, Daniel J

    2014-05-01

    The minimally invasive oesophagectomy (MIO) approach offers a number of advantages over open approaches including reduced discomfort, shorter length of stay and a faster recovery to baseline status. On the other hand, minimally invasive procedures typically are longer and consume greater disposable instrumentation, potentially resulting in a greater overall cost. The objective of this study was to compare costs associated with various oesophagectomy approaches for oesophageal cancer. An institutional Resource Information Management System (RIMS) was queried for cost data relating to hospital expenditures (as opposed to billings or collections). The RIMS was searched for patients undergoing oesophagectomy for oesophageal cancer between 2003 and 2012 via minimally invasive, open transthoracic (OTT) (including Ivor Lewis, modified McKeown or thoracoabdominal) or transhiatal approaches. Patients that were converted from minimally invasive to open, or involved hybrid procedures, were excluded. A total of 160 oesophagectomies were identified, including 61 minimally invasive, 35 open transthoracic and 64 transhiatal. Costs on the day of surgery averaged higher in the MIO group ($12 476 ± 2190) compared with the open groups, OTT ($8202 ± 2512, P < 0.0001) or OTH ($5809 ± 2575, P < 0.0001). The median costs associated with the entire hospitalization also appear to be higher in the MIO group ($25 935) compared with OTT ($24 440) and OTH ($15 248). The average length of stay was lowest in the MIO group (11 ± 9 days) compared with OTT (19 ± 18 days, P = 0.006) and OTH (18 ± 28 days P = 0.07). The operative mortality was similar in the three groups (MIO = 3%, OTT = 9% and OTH = 3%). The operating theatre costs associated with minimally invasive oesophagectomy are significantly higher than OTT or OTH approaches. Unfortunately, a shorter hospital stay after MIO does not consistently offset higher surgical expense, as total hospital costs trend higher in the MIO patients. In

  9. AP1000 construction schedule

    International Nuclear Information System (INIS)

    Winters, J.W.

    2001-01-01

    Westinghouse performed this study as part of EPRI interest in advancing the use of computer aided processes to reduce the cost of nuclear power plants. EPRI believed that if one could relate appropriate portions of an advanced light water reactor plant model to activities in its construction sequence, and this relationship could be portrayed visually, then optimization of the construction sequence could be developed as never before. By seeing a 3-D representation of the plant at any point in its construction sequence, more informed decisions can be made on the feasibility or attractiveness of follow on or parallel steps in the sequence. The 3-D representation of construction as a function of time (4-D) could also increase the confidence of potential investors concerning the viability of the schedule and the plant ultimate cost. This study performed by Westinghouse confirmed that it is useful to be able to visualize a plant construction in 3-D as a function of time in order to optimize the sequence of construction activities. (author)

  10. TECHNICAL COORDINATION SCHEDULE & INTEGRATION

    CERN Multimedia

    W. Zeuner

    Introduction The endgame of CMS installation in the underground cavern is in full swing, with several major milestones having been passed since the last CMS week. The Tracker was installed inside the Vactank just before the CERN end-of-year shutdown. Shortly after the reopening in 2008, the two remaining endcap disks, YE-2 and YE-1, were lowered, marking the completion of eight years of assembly in the surface building SX5. The remaining tasks, before the detector can be closed for the Cosmic Run At Four Tesla (CRAFT), are the installation of the thermal shields, the cabling of the negative endcap, the cabling of the tracker and the beam pipe installation. In addition to these installation tasks, a test closure of the positive endcap is planned just before the installation of the central beam pipe. The schedule is tight and complicated but the goal to close CMS by the end of May for a cosmic test with magnetic field remains feasible. Safety With all large components now being underground, the shortage...

  11. "Taller and Shorter": Human 3-D Spatial Memory Distorts Familiar Multilevel Buildings.

    Directory of Open Access Journals (Sweden)

    Thomas Brandt

    Full Text Available Animal experiments report contradictory findings on the presence of a behavioural and neuronal anisotropy exhibited in vertical and horizontal capabilities of spatial orientation and navigation. We performed a pointing experiment in humans on the imagined 3-D direction of the location of various invisible goals that were distributed horizontally and vertically in a familiar multilevel hospital building. The 21 participants were employees who had worked for years in this building. The hypothesis was that comparison of the experimentally determined directions and the true directions would reveal systematic inaccuracy or dimensional anisotropy of the localizations. The study provides first evidence that the internal representation of a familiar multilevel building was distorted compared to the dimensions of the true building: vertically 215% taller and horizontally 51% shorter. This was not only demonstrated in the mathematical reconstruction of the mental model based on the analysis of the pointing experiments but also by the participants' drawings of the front view and the ground plan of the building. Thus, in the mental model both planes were altered in different directions: compressed for the horizontal floor plane and stretched for the vertical column plane. This could be related to human anisotropic behavioural performance of horizontal and vertical navigation in such buildings.

  12. Risky family processes prospectively forecast shorter telomere length mediated through negative emotions.

    Science.gov (United States)

    Brody, Gene H; Yu, Tianyi; Shalev, Idan

    2017-05-01

    This study was designed to examine prospective associations of risky family environments with subsequent levels of negative emotions and peripheral blood mononuclear cell telomere length (TL), a marker of cellular aging. A second purpose was to determine whether negative emotions mediate the hypothesized link between risky family processes and diminished telomere length. Participants were 293 adolescents (age 17 years at the first assessment) and their primary caregivers. Caregivers provided data on risky family processes when the youths were age 17 years, youths reported their negative emotions at age 18 years, and youths' TL was assayed from a blood sample at age 22 years. The results revealed that (a) risky family processes forecast heightened negative emotions (β = .316, p emotions forecast shorter TL (β = -.187, p = .012), and (c) negative emotions served as a mediator connecting risky family processes with diminished TL (indirect effect = -0.012, 95% CI [-0.036, -0.002]). These findings are consistent with the hypothesis that risky family processes presage premature cellular aging through effects on negative emotions, with potential implications for lifelong health. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Effects of shorter versus longer storage time of transfused red blood cells in adult ICU patients

    DEFF Research Database (Denmark)

    Rygård, Sofie L; Jonsson, Andreas B; Madsen, Martin B

    2018-01-01

    on the effects of shorter versus longer storage time of transfused RBCs on outcomes in ICU patients. METHODS: We conducted a systematic review with meta-analyses and trial sequential analyses (TSA) of randomised clinical trials including adult ICU patients transfused with fresher versus older or standard issue...... blood. RESULTS: We included seven trials with a total of 18,283 randomised ICU patients; two trials of 7504 patients were judged to have low risk of bias. We observed no effects of fresher versus older blood on death (relative risk 1.04, 95% confidence interval (CI) 0.97-1.11; 7349 patients; TSA......-adjusted CI 0.93-1.15), adverse events (1.26, 0.76-2.09; 7332 patients; TSA-adjusted CI 0.16-9.87) or post-transfusion infections (1.07, 0.96-1.20; 7332 patients; TSA-adjusted CI 0.90-1.27). The results were unchanged by including trials with high risk of bias. TSA confirmed the results and the required...

  14. Gain of chromosome arm 1q in atypical meningioma correlates with shorter progression-free survival.

    LENUS (Irish Health Repository)

    2012-02-01

    Aims: Atypical (WHO grade II) meningiomas have moderately high recurrence rates; even for completely resected tumours, approximately one-third will recur. Post-operative radiotherapy (RT) may aid local control and improve survival, but carries the risk of side effects. More accurate prediction of recurrence risk is therefore needed for patients with atypical meningioma. Previously, we used high-resolution array CGH to identify genetic variations in 47 primary atypical meningiomas and found that approximately 60% of tumors show gain of 1q at 1q25.1 and 1q25.3 to 1q32.1 and that 1q gain appeared to correlate with shorter progression-free survival. This study aimed to validate and extend these findings in an independent sample. Methods: 86 completely resected atypical meningiomas (with 25 recurrences) from two neurosurgical centres in Ireland were identified and clinical follow up was obtained. Utilizing a dual-colour interphase FISH assay, 1q gain was assessed using BAC probes directed against 1q25.1 and 1q32.1. Results: The results confirm the high prevalence of 1q gain at these loci in atypical meningiomas. We further show that gain at 1q32.1 and age each correlate with progression-free survival in patients who have undergone complete surgical resection of atypical meningiomas. Conclusions: These independent findings suggest that assessment of 1q copy number status can add clinically useful information for the management of patients with atypical meningiomas.

  15. Greater reproductive investment, but shorter lifespan, in agrosystem than in natural-habitat toads

    Directory of Open Access Journals (Sweden)

    Francisco Javier Zamora-Camacho

    2017-09-01

    Full Text Available Global amphibian decline is due to several factors: habitat loss, anthropization, pollution, emerging diseases, and global warming. Amphibians, with complex life cycles, are particularly susceptible to habitat alterations, and their survival may be impaired in anthropized habitats. Increased mortality is a well-known consequence of anthropization. Life-history theory predicts higher reproductive investment when mortality is increased. In this work, we compared age, body size, and different indicators of reproductive investment, as well as prey availability, in natterjack toads (Epidalea calamita from agrosystems and adjacent natural pine groves in Southwestern Spain. Mean age was lower in agrosystems than in pine groves, possibly as a consequence of increased mortality due to agrosystem environmental stressors. Remarkably, agrosystem toads were larger despite being younger, suggesting accelerated growth rate. Although we detected no differences in prey availability between habitats, artificial irrigation could shorten aestivation in agrosystems, thus increasing energy trade. Moreover, agrosystem toads exhibited increased indicators of reproductive investment. In the light of life-history theory, agrosystem toads might compensate for lesser reproductive events—due to shorter lives—with a higher reproductive investment in each attempt. Our results show that agrosystems may alter demography, which may have complex consequences on both individual fitness and population stability.

  16. "Taller and Shorter": Human 3-D Spatial Memory Distorts Familiar Multilevel Buildings.

    Science.gov (United States)

    Brandt, Thomas; Huber, Markus; Schramm, Hannah; Kugler, Günter; Dieterich, Marianne; Glasauer, Stefan

    2015-01-01

    Animal experiments report contradictory findings on the presence of a behavioural and neuronal anisotropy exhibited in vertical and horizontal capabilities of spatial orientation and navigation. We performed a pointing experiment in humans on the imagined 3-D direction of the location of various invisible goals that were distributed horizontally and vertically in a familiar multilevel hospital building. The 21 participants were employees who had worked for years in this building. The hypothesis was that comparison of the experimentally determined directions and the true directions would reveal systematic inaccuracy or dimensional anisotropy of the localizations. The study provides first evidence that the internal representation of a familiar multilevel building was distorted compared to the dimensions of the true building: vertically 215% taller and horizontally 51% shorter. This was not only demonstrated in the mathematical reconstruction of the mental model based on the analysis of the pointing experiments but also by the participants' drawings of the front view and the ground plan of the building. Thus, in the mental model both planes were altered in different directions: compressed for the horizontal floor plane and stretched for the vertical column plane. This could be related to human anisotropic behavioural performance of horizontal and vertical navigation in such buildings.

  17. Manejo de irrigação para o feijão-de-metro, nas fases vegetativa e produtiva, em ambiente protegido Irrigation scheduling for asparagus bean in vegetative and productive stages in greenhouse

    Directory of Open Access Journals (Sweden)

    Wellington G. da Silva

    2012-09-01

    Full Text Available O manejo adequado da irrigação é uma prática agrícola que requer informações para cada cultura explorada, em particular nas fases fenológicas do ciclo produtivo pois muitas espécies possuem períodos críticos durante os quais o estresse hídrico causa sérias reduções na produção. Este trabalho teve, como objetivo, avaliar o efeito de cinco níveis de potencial matricial de água no solo sobre o crescimento e produção do feijão-de-metro. O experimento foi conduzido em casa de vegetação, na área experimental pertencente ao Departamento de Engenharia da Universidade Federal de Lavras, Lavras, MG. O delineamento experimental foi o de blocos casualizados, em esquema fatorial 5 x 2, com quatro repetições. Os tratamentos foram constituídos de cinco potenciais matriciais de água no solo como indicativos do momento de irrigar (-15, -35, -55, -75 e -95 kPa, em duas fases fenológicas (vegetativa e produtiva, monitorados por sensores instalados a 0,15 m de profundidade. Os resultados permitiram concluir que a fase mais sensível ao déficit hídrico foi a produtiva e que a irrigação realizada no potencial matricial em torno de -15 kPa induziu a melhor resposta da cultura quanto ao desenvolvimento, produção e qualidade das vagens.Proper irrigation water management requires knowledge on each exploited crop; particularly regarding vegetative and productive phases since many species have critical periods during which water stress causes serious yield reductions. This study was undertaken so as to assess the effect of five matric potential levels on asparagus bean growth and yield. The experiment was conducted under greenhouse conditions at the experimental area of Department of Engineering, Federal University of Lavras, Lavras, MG. The experimental design was randomized blocks in factorial 5 x 2. The treatments consisted of five matric potentials as indicative of the irrigation scheduling -15 -35 -55 -75 -95 kPa and at two

  18. Application of Tabu Search Algorithm in Job Shop Scheduling

    Directory of Open Access Journals (Sweden)

    Betrianis Betrianis

    2010-10-01

    Full Text Available Tabu Search is one of local search methods which is used to solve the combinatorial optimization problem. This method aimed is to make the searching process of the best solution in a complex combinatorial optimization problem(np hard, ex : job shop scheduling problem, became more effective, in a less computational time but with no guarantee to optimum solution.In this paper, tabu search is used to solve the job shop scheduling problem consists of 3 (three cases, which is ordering package of September, October and November with objective of minimizing makespan (Cmax. For each ordering package, there is a combination for initial solution and tabu list length. These result then  compared with 4 (four other methods using basic dispatching rules such as Shortest Processing Time (SPT, Earliest Due Date (EDD, Most Work Remaining (MWKR dan First Come First Served (FCFS. Scheduling used Tabu Search Algorithm is sensitive for variables changes and gives makespan shorter than scheduling used by other four methods.

  19. Gain scheduling using the Youla parameterization

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Stoustrup, Jakob

    1999-01-01

    Gain scheduling controllers are considered in this paper. The gain scheduling problem where the scheduling parameter vector cannot be measured directly, but needs to be estimated is considered. An estimation of the scheduling vector has been derived by using the Youla parameterization. The use...... in connection with H_inf gain scheduling controllers....

  20. Flow-shop scheduling problem under uncertainties: Review and trends

    Directory of Open Access Journals (Sweden)

    Eliana María González-Neira

    2017-03-01

    Full Text Available Among the different tasks in production logistics, job scheduling is one of the most important at the operational decision-making level to enable organizations to achieve competiveness. Scheduling consists in the allocation of limited resources to activities over time in order to achieve one or more optimization objectives. Flow-shop (FS scheduling problems encompass the sequencing processes in environments in which the activities or operations are performed in a serial flow. This type of configuration includes assembly lines and the chemical, electronic, food, and metallurgical industries, among others. Scheduling has been mostly investigated for the deterministic cases, in which all parameters are known in advance and do not vary over time. Nevertheless, in real-world situations, events are frequently subject to uncertainties that can affect the decision-making process. Thus, it is important to study scheduling and sequencing activities under uncertainties since they can cause infeasibilities and disturbances. The purpose of this paper is to provide a general overview of the FS scheduling problem under uncertainties and its role in production logistics and to draw up opportunities for further research. To this end, 100 papers about FS and flexible flow-shop scheduling problems published from 2001 to October 2016 were analyzed and classified. Trends in the reviewed literature are presented and finally some research opportunities in the field are proposed.

  1. Constraint-based scheduling applying constraint programming to scheduling problems

    CERN Document Server

    Baptiste, Philippe; Nuijten, Wim

    2001-01-01

    Constraint Programming is a problem-solving paradigm that establishes a clear distinction between two pivotal aspects of a problem: (1) a precise definition of the constraints that define the problem to be solved and (2) the algorithms and heuristics enabling the selection of decisions to solve the problem. It is because of these capabilities that Constraint Programming is increasingly being employed as a problem-solving tool to solve scheduling problems. Hence the development of Constraint-Based Scheduling as a field of study. The aim of this book is to provide an overview of the most widely used Constraint-Based Scheduling techniques. Following the principles of Constraint Programming, the book consists of three distinct parts: The first chapter introduces the basic principles of Constraint Programming and provides a model of the constraints that are the most often encountered in scheduling problems. Chapters 2, 3, 4, and 5 are focused on the propagation of resource constraints, which usually are responsibl...

  2. The Effect of Shorter Treatment Regimens for Hepatitis C on Population Health and Under Fixed Budgets.

    Science.gov (United States)

    Morgan, Jake R; Kim, Arthur Y; Naggie, Susanna; Linas, Benjamin P

    2018-01-01

    Direct acting antiviral hepatitis C virus (HCV) therapies are highly effective but costly. Wider adoption of an 8-week ledipasvir/sofosbuvir treatment regimen could result in significant savings, but may be less efficacious compared with a 12-week regimen. We evaluated outcomes under a constrained budget and cost-effectiveness of 8 vs 12 weeks of therapy in treatment-naïve, noncirrhotic, genotype 1 HCV-infected black and nonblack individuals and considered scenarios of IL28B and NS5A resistance testing to determine treatment duration in sensitivity analyses. We developed a decision tree to use in conjunction with Monte Carlo simulation to investigate the cost-effectiveness of recommended treatment durations and the population health effect of these strategies given a constrained budget. Outcomes included the total number of individuals treated and attaining sustained virologic response (SVR) given a constrained budget and incremental cost-effectiveness ratios. We found that treating eligible (treatment-naïve, noncirrhotic, HCV-RNA budget among both black and nonblack individuals, and our results suggested that NS5A resistance testing is cost-effective. Eight-week therapy provides good value, and wider adoption of shorter treatment could allow more individuals to attain SVR on the population level given a constrained budget. This analysis provides an evidence base to justify movement of the 8-week regimen to the preferred regimen list for appropriate patients in the HCV treatment guidelines and suggests expanding that recommendation to black patients in settings where cost and relapse trade-offs are considered.

  3. Shorter Ground Contact Time and Better Running Economy: Evidence From Female Kenyan Runners.

    Science.gov (United States)

    Mooses, Martin; Haile, Diresibachew W; Ojiambo, Robert; Sang, Meshack; Mooses, Kerli; Lane, Amy R; Hackney, Anthony C

    2018-06-25

    Mooses, M, Haile, DW, Ojiambo, R, Sang, M, Mooses, K, Lane, AR, and Hackney, AC. Shorter ground contact time and better running economy: evidence from female Kenyan runners. J Strength Cond Res XX(X): 000-000, 2018-Previously, it has been concluded that the improvement in running economy (RE) might be considered as a key to the continued improvement in performance when no further increase in V[Combining Dot Above]O2max is observed. To date, RE has been extensively studied among male East African distance runners. By contrast, there is a paucity of data on the RE of female East African runners. A total of 10 female Kenyan runners performed 3 × 1,600-m steady-state run trials on a flat outdoor clay track (400-m lap) at the intensities that corresponded to their everyday training intensities for easy, moderate, and fast running. Running economy together with gait characteristics was determined. Participants showed moderate to very good RE at the first (202 ± 26 ml·kg·km) and second (188 ± 12 ml·kg·km) run trials, respectively. Correlation analysis revealed significant relationship between ground contact time (GCT) and RE at the second run (r = 0.782; p = 0.022), which represented the intensity of anaerobic threshold. This study is the first to report the RE and gait characteristics of East African female athletes measured under everyday training settings. We provided the evidence that GCT is associated with the superior RE of the female Kenyan runners.

  4. Less is more: latent learning is maximized by shorter training sessions in auditory perceptual learning.

    Science.gov (United States)

    Molloy, Katharine; Moore, David R; Sohoglu, Ediz; Amitay, Sygal

    2012-01-01

    The time course and outcome of perceptual learning can be affected by the length and distribution of practice, but the training regimen parameters that govern these effects have received little systematic study in the auditory domain. We asked whether there was a minimum requirement on the number of trials within a training session for learning to occur, whether there was a maximum limit beyond which additional trials became ineffective, and whether multiple training sessions provided benefit over a single session. We investigated the efficacy of different regimens that varied in the distribution of practice across training sessions and in the overall amount of practice received on a frequency discrimination task. While learning was relatively robust to variations in regimen, the group with the shortest training sessions (∼8 min) had significantly faster learning in early stages of training than groups with longer sessions. In later stages, the group with the longest training sessions (>1 hr) showed slower learning than the other groups, suggesting overtraining. Between-session improvements were inversely correlated with performance; they were largest at the start of training and reduced as training progressed. In a second experiment we found no additional longer-term improvement in performance, retention, or transfer of learning for a group that trained over 4 sessions (∼4 hr in total) relative to a group that trained for a single session (∼1 hr). However, the mechanisms of learning differed; the single-session group continued to improve in the days following cessation of training, whereas the multi-session group showed no further improvement once training had ceased. Shorter training sessions were advantageous because they allowed for more latent, between-session and post-training learning to emerge. These findings suggest that efficient regimens should use short training sessions, and optimized spacing between sessions.

  5. Are Shorter Article Titles More Attractive for Citations? Cross-sectional Study of 22 Scientific Journals

    Science.gov (United States)

    Habibzadeh, Farrokh; Yadollahie, Mahboobeh

    2010-01-01

    Aim To investigate the correlation between the length of the title of a scientific article and the number of citations it receives, in view of the common editorial call for shorter titles. Methods Title and the number of citations to all articles published in 2005 in 22 arbitrarily chosen English-language journals (n = 9031) were retrieved from citation database Scopus. The 2008 journal impact factors of these 22 journals were also retrieved from Thomson Reuters’ Journal Citation Report (JCR). Assuming the article title length as the independent variable, and the number of citations to the article as the dependent variable, a linear regression model was applied. Results The slope of the regression line for some journals (n = 6, when titles were measured in characters but 7 when titles were measured in words) was negative – none was significantly different from 0. The overall slope for all journals was 0.140 (when titles were measured in characters) and 0.778 (when titles were measured in words), significantly different from 0 (P articles with longer titles received more citations – Spearman ρ = 0.266 – when titles were measured in characters, and ρ = 0.244 when titles were measured in words (P 10 and for 2 out of 14 journals with impact factor <10 (P < 0.001, Fisher exact test). Conclusion Longer titles seem to be associated with higher citation rates. This association is more pronounced for journals with high impact factors. Editors who insist on brief and concise titles should perhaps update the guidelines for authors of their journals and have more flexibility regarding the length of the title. PMID:20401960

  6. Shorter exposures to harder X-rays trigger early apoptotic events in Xenopus laevis embryos.

    Directory of Open Access Journals (Sweden)

    JiaJia Dong

    Full Text Available BACKGROUND: A long-standing conventional view of radiation-induced apoptosis is that increased exposure results in augmented apoptosis in a biological system, with a threshold below which radiation doses do not cause any significant increase in cell death. The consequences of this belief impact the extent to which malignant diseases and non-malignant conditions are therapeutically treated and how radiation is used in combination with other therapies. Our research challenges the current dogma of dose-dependent induction of apoptosis and establishes a new parallel paradigm to the photoelectric effect in biological systems. METHODOLOGY/PRINCIPAL FINDINGS: We explored how the energy of individual X-ray photons and exposure time, both factors that determine the total dose, influence the occurrence of cell death in early Xenopus embryo. Three different experimental scenarios were analyzed and morphological and biochemical hallmarks of apoptosis were evaluated. Initially, we examined cell death events in embryos exposed to increasing incident energies when the exposure time was preset. Then, we evaluated the embryo's response when the exposure time was augmented while the energy value remained constant. Lastly, we studied the incidence of apoptosis in embryos exposed to an equal total dose of radiation that resulted from increasing the incoming energy while lowering the exposure time. CONCLUSIONS/SIGNIFICANCE: Overall, our data establish that the energy of the incident photon is a major contributor to the outcome of the biological system. In particular, for embryos exposed under identical conditions and delivered the same absorbed dose of radiation, the response is significantly increased when shorter bursts of more energetic photons are used. These results suggest that biological organisms display properties similar to the photoelectric effect in physical systems and provide new insights into how radiation-mediated apoptosis should be understood and

  7. Hypermetabolism in ALS is associated with greater functional decline and shorter survival.

    Science.gov (United States)

    Steyn, Frederik J; Ioannides, Zara A; van Eijk, Ruben P A; Heggie, Susan; Thorpe, Kathryn A; Ceslis, Amelia; Heshmat, Saman; Henders, Anjali K; Wray, Naomi R; van den Berg, Leonard H; Henderson, Robert D; McCombe, Pamela A; Ngo, Shyuan T

    2018-04-29

    To determine the prevalence of hypermetabolism, relative to body composition, in amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and survival. Fifty-eight patients with clinically definite or probable ALS as defined by El Escorial criteria, and 58 age and sex-matched control participants underwent assessment of energy expenditure. Our primary outcome was the prevalence of hypermetabolism in cases and controls. Longitudinal changes in clinical parameters between hypermetabolic and normometabolic patients with ALS were determined for up to 12 months following metabolic assessment. Survival was monitored over a 30-month period following metabolic assessment. Hypermetabolism was more prevalent in patients with ALS than controls (41% vs 12%, adjusted OR=5.4; pALS. Mean lower motor neuron score (SD) was greater in hypermetabolic patients when compared with normometabolic patients (4 (0.3) vs 3 (0.7); p=0.04). In the 12 months following metabolic assessment, there was a greater change in Revised ALS Functional Rating Scale score in hypermetabolic patients when compared with normometabolic patients (-0.68 points/month vs -0.39 points/month; p=0.01). Hypermetabolism was inversely associated with survival. Overall, hypermetabolism increased the risk of death during follow-up to 220% (HR 3.2, 95% CI 1.1 to 9.4, p=0.03). Hypermetabolic patients with ALS have a greater level of lower motor neuron involvement, faster rate of functional decline and shorter survival. The metabolic index could be important for informing prognosis in ALS. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Distributed continuous energy scheduling for dynamic virtual power plants

    International Nuclear Information System (INIS)

    Niesse, Astrid

    2015-01-01

    This thesis presents DynaSCOPE as distributed control method for continuous energy scheduling for dynamic virtual power plants (DVPP). DVPPs aggregate the flexibility of distributed energy units to address current energy markets. As an extension of the Virtual Power Plant concept they show high dynamics in aggregation and operation of energy units. Whereas operation schedules are set up for all energy units in a day-ahead planning procedure, incidents may render these schedules infeasible during execution, like deviation from prognoses or outages. Thus, a continuous scheduling process is needed to ensure product fulfillment. With DynaSCOPE, software agents representing single energy units solve this problem in a completely distributed heuristic approach. Using a stepped concept, several damping mechanisms are applied to allow minimum disturbance while continuously trying to fulfill the product as contracted at the market.

  9. Scheduling of resource-constrained projects

    CERN Document Server

    Klein, Robert

    2000-01-01

    Project management has become a widespread instrument enabling organizations to efficiently master the challenges of steadily shortening product life cycles, global markets and decreasing profit margins. With projects increasing in size and complexity, their planning and control represents one of the most crucial management tasks. This is especially true for scheduling, which is concerned with establishing execution dates for the sub-activities to be performed in order to complete the project. The ability to manage projects where resources must be allocated between concurrent projects or even sub-activities of a single project requires the use of commercial project management software packages. However, the results yielded by the solution procedures included are often rather unsatisfactory. Scheduling of Resource-Constrained Projects develops more efficient procedures, which can easily be integrated into software packages by incorporated programming languages, and thus should be of great interest for practiti...

  10. Automated Planning and Scheduling for Space Mission Operations

    Science.gov (United States)

    Chien, Steve; Jonsson, Ari; Knight, Russell

    2005-01-01

    Research Trends: a) Finite-capacity scheduling under more complex constraints and increased problem dimensionality (subcontracting, overtime, lot splitting, inventory, etc.) b) Integrated planning and scheduling. c) Mixed-initiative frameworks. d) Management of uncertainty (proactive and reactive). e) Autonomous agent architectures and distributed production management. e) Integration of machine learning capabilities. f) Wider scope of applications: 1) analysis of supplier/buyer protocols & tradeoffs; 2) integration of strategic & tactical decision-making; and 3) enterprise integration.

  11. Immunization Schedules for Infants and Children

    Science.gov (United States)

    ... ACIP Vaccination Recommendations Why Immunize? Vaccines: The Basics Immunization Schedule for Infants and Children (Birth through 6 ... any questions please talk to your doctor. 2018 Immunization Schedule Recommended Vaccinations for Infants and Children Schedule ...

  12. Operating Theatre Planning and Scheduling.

    NARCIS (Netherlands)

    Hans, Elias W.; Vanberkel, P.T.; Hall, R.

    2012-01-01

    In this chapter we present a number of approaches to operating theatre planning and scheduling. We organize these approaches hierarchically which serves to illustrate the breadth of problems confronted by researchers. At each hierarchicalplanning level we describe common problems, solution

  13. Schedule Sales Query Raw Data

    Data.gov (United States)

    General Services Administration — Schedule Sales Query presents sales volume figures as reported to GSA by contractors. The reports are generated as quarterly reports for the current year and the...

  14. Multiagent scheduling models and algorithms

    CERN Document Server

    Agnetis, Alessandro; Gawiejnowicz, Stanisław; Pacciarelli, Dario; Soukhal, Ameur

    2014-01-01

    This book presents multi-agent scheduling models in which subsets of jobs sharing the same resources are evaluated by different criteria. It discusses complexity results, approximation schemes, heuristics and exact algorithms.

  15. Executive Schedule C System (ESCS)

    Data.gov (United States)

    Office of Personnel Management — Used to store information on Federal employees in the Senior Executive Service (SES) and appointed employees in the Schedule C System. Every four years, just after...

  16. Future aircraft networks and schedules

    Science.gov (United States)

    Shu, Yan

    2011-07-01

    Because of the importance of air transportation scheduling, the emergence of small aircraft and the vision of future fuel-efficient aircraft, this thesis has focused on the study of aircraft scheduling and network design involving multiple types of aircraft and flight services. It develops models and solution algorithms for the schedule design problem and analyzes the computational results. First, based on the current development of small aircraft and on-demand flight services, this thesis expands a business model for integrating on-demand flight services with the traditional scheduled flight services. This thesis proposes a three-step approach to the design of aircraft schedules and networks from scratch under the model. In the first step, both a frequency assignment model for scheduled flights that incorporates a passenger path choice model and a frequency assignment model for on-demand flights that incorporates a passenger mode choice model are created. In the second step, a rough fleet assignment model that determines a set of flight legs, each of which is assigned an aircraft type and a rough departure time is constructed. In the third step, a timetable model that determines an exact departure time for each flight leg is developed. Based on the models proposed in the three steps, this thesis creates schedule design instances that involve almost all the major airports and markets in the United States. The instances of the frequency assignment model created in this thesis are large-scale non-convex mixed-integer programming problems, and this dissertation develops an overall network structure and proposes iterative algorithms for solving these instances. The instances of both the rough fleet assignment model and the timetable model created in this thesis are large-scale mixed-integer programming problems, and this dissertation develops subproblem schemes for solving these instances. Based on these solution algorithms, this dissertation also presents

  17. Construction schedules slack time minimizing

    Science.gov (United States)

    Krzemiński, Michał

    2017-07-01

    The article presents two copyright models for minimizing downtime working brigades. Models have been developed for construction schedules performed using the method of work uniform. Application of flow shop models is possible and useful for the implementation of large objects, which can be divided into plots. The article also presents a condition describing gives which model should be used, as well as a brief example of optimization schedule. The optimization results confirm the legitimacy of the work on the newly-developed models.

  18. Shorter sleep duration is associated with social impairment and comorbidities in ASD.

    Science.gov (United States)

    Veatch, Olivia J; Sutcliffe, James S; Warren, Zachary E; Keenan, Brendan T; Potter, Melissa H; Malow, Beth A

    2017-07-01

    Sleep disturbance, particularly insomnia, is common in children with autism spectrum disorders (ASD). Furthermore, disturbed sleep affects core symptoms and other related comorbidities. Understanding the causes and consequences of sleep disturbances in children with ASD is an important step toward mitigating these symptoms. To better understand the connection between sleep duration and ASD severity, we analyzed ASD-related symptoms using the Autism Diagnostic Interview-Revised (ADI-R), Autism Diagnostic Observation Schedule (ADOS), IQ scores, and parent reports of the average amount of time slept per night that were available in the medical histories of 2,714 children with ASD in the Simons Simplex Collection (SSC). The mean (SD) sleep duration was 555 minutes. Sleep duration and severity of core ASD symptoms were negatively correlated, and sleep duration and IQ scores were positively correlated. Regression results indicated that more severe social impairment, primarily a failure to develop peer relationships, is the core symptom most strongly associated with short sleep duration. Furthermore, increased severity for numerous maladaptive behaviors assessed on the Child Behavior Checklist, as well as reports of attention deficit disorder, depressive disorder, and obsessive compulsive disorder were associated with short sleep duration. Severity scores for social/communication impairment and restricted and repetitive behaviors (RRB) were increased, and IQ scores were decreased, for children reported to sleep ≤420 minutes per night (lower 5th percentile) compared to children sleeping ≥660 minutes (upper 95th percentile). Our results indicate that reduced amounts of sleep are related to more severe symptoms in children with ASD. Autism Res 2017. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Autism Res 2017, 10: 1221-1238. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. © 2017 International Society for Autism

  19. Shorter Hospital Stays and Lower Costs for Rivaroxaban Compared With Warfarin for Venous Thrombosis Admissions.

    Science.gov (United States)

    Margolis, Jay M; Deitelzweig, Steven; Kline, Jeffrey; Tran, Oth; Smith, David M; Bookhart, Brahim; Crivera, Concetta; Schein, Jeff

    2016-10-06

    % confidence interval, $8035-$8739]; warfarin $10 275 [95% confidence interval, $9842-$10 708]). Rivaroxaban was associated with significantly shorter hospital LOS and lower hospitalization costs compared with warfarin. © 2016 The Authors, Janssen Scientific Affairs, LLC, and Truven Health Analytics. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  20. Pulmonary Embolism Inpatients Treated With Rivaroxaban Had Shorter Hospital Stays and Lower Costs Compared With Warfarin.

    Science.gov (United States)

    Margolis, Jay M; Deitelzweig, Steven; Kline, Jeffrey; Tran, Oth; Smith, David M; Crivera, Concetta; Bookhart, Brahim; Schein, Jeff

    2016-11-01

    Using real-world data, this study compares inpatient length of stay (LOS) and costs for patients with a primary diagnosis of pulmonary embolism (PE) initiating treatment with oral anticoagulation with rivaroxaban versus warfarin. Hospitalizations from MarketScan's Hospital Drug Database were selected from November 1, 2012, through December 31, 2013, for adults with a primary diagnosis of PE initiating treatment with rivaroxaban or warfarin. Warfarin patients were matched 1:1 to rivaroxaban patients using exact and propensity score matching. Hospital LOS, treatment patterns, and hospitalization costs were evaluated. Matched cohorts included 751 rivaroxaban-treated patients and 751 warfarin-treated patients. Adjusted mean LOS was 3.77 days for rivaroxaban patients (95% CI, 3.66-3.87 days) and 5.48 days for warfarin patients (95% CI, 5.33-5.63 days; P < .001). Mean (SD) LOS was shorter for patients taking rivaroxaban whether admission was for provoked PE (rivaroxaban: 5.2 [5.1] days; warfarin: 7.0 [6.5] days; P < .001) or unprovoked PE (rivaroxaban: 3.4 [2.3] days; warfarin: 5.1 [2.7] days; P < .001). Mean (SD) days from first dose to discharge were 2.5 (1.7) (rivaroxaban) and 4.0 (2.9) (warfarin) when initiated with parenteral anticoagulants (P < .001) and 2.7 (1.7) (rivaroxaban) and 4.0 (2.2) (warfarin) without parenteral anticoagulants (P < .001). The rivaroxaban cohort incurred significantly lower unadjusted mean (SD) hospitalization costs (rivaroxaban: $8473 [$9105]; warfarin: $10,291 [$9185]; P < .001), confirmed by covariate adjustment with generalized linear modeling estimating predicted mean hospitalization costs of $8266 for rivaroxaban patients (95% CI, $7851-$8681) and $10,511 for warfarin patients (95% CI, $10,031-$10,992; P < .001). patients with PE treated with rivaroxaban incurred significantly lower hospitalization costs by $2245 per admission compared with patients treated with warfarin, which was attributable to cost offsets from 1.71 fewer days of

  1. The return trip is felt shorter only postdictively: A psychophysiological study of the return trip effect [corrected].

    Directory of Open Access Journals (Sweden)

    Ryosuke Ozawa

    Full Text Available The return trip often seems shorter than the outward trip even when the distance and actual time are identical. To date, studies on the return trip effect have failed to confirm its existence in a situation that is ecologically valid in terms of environment and duration. In addition, physiological influences as part of fundamental timing mechanisms in daily activities have not been investigated in the time perception literature. The present study compared round-trip and non-round-trip conditions in an ecological situation. Time estimation in real time and postdictive estimation were used to clarify the situations where the return trip effect occurs. Autonomic nervous system activity was evaluated from the electrocardiogram using the Lorenz plot to demonstrate the relationship between time perception and physiological indices. The results suggest that the return trip effect is caused only postdictively. Electrocardiographic analysis revealed that the two experimental conditions induced different responses in the autonomic nervous system, particularly in sympathetic nervous function, and that parasympathetic function correlated with postdictive timing. To account for the main findings, the discrepancy between the two time estimates is discussed in the light of timing strategies, i.e., prospective and retrospective timing, which reflect different emphasis on attention and memory processes. Also each timing method, i.e., the verbal estimation, production or comparative judgment, has different characteristics such as the quantification of duration in time units or knowledge of the target duration, which may be responsible for the discrepancy. The relationship between postdictive time estimation and the parasympathetic nervous system is also discussed.

  2. The applicability of knowledge-based scheduling to the utilities industry

    International Nuclear Information System (INIS)

    Yoshimoto, G.; Gargan, R. Jr.; Duggan, P.

    1992-01-01

    The Electric Power Research Institute (EPRI), Nuclear Power Division, has identified the three major goals of high technology applications for nuclear power plants. These goals are to enhance power production through increasing power generation efficiency, to increase productivity of the operations, and to reduce the threats to the safety of the plant. Our project responds to the second goal by demonstrating that significant productivity increases can be achieved for outage maintenance operations based on existing knowledge-based scheduling technology. Its use can also mitigate threats to potential safety problems by means of the integration of risk assessment features into the scheduler. The scheduling approach uses advanced techniques enabling the automation of the routine scheduling decision process that previously was handled by people. The process of removing conflicts in scheduling is automated. This is achieved by providing activity representations that allow schedulers to express a variety of different scheduling constraints and by implementing scheduling mechanisms that simulate kinds of processes that humans use to find better solutions from a large number of possible solutions. This approach allows schedulers to express detailed constraints between activities and other activities, resources (material and personnel), and requirements that certain states exist for their execution. Our scheduler has already demonstrated its benefit to improving the shuttle processing flow management at Kennedy Space Center. Knowledge-based scheduling techniques should be examined by utilities industry researchers, developers, operators and management for application to utilities planning problems because of its great cost benefit potential. 4 refs., 4 figs

  3. Prioritizing sleep for healthy work schedules

    Science.gov (United States)

    2012-01-01

    Good sleep is advantageous to the quality of life. Sleep-related benefits are particularly helpful for the working class, since poor or inadequate amounts of sleep degrade work productivity and overall health. This review paper explores the essential role of sleep in healthy work schedules and primarily focuses on the timing of sleep in relation to the work period (that is, before, during and after work). Data from laboratory, field and modeling studies indicate that consistent amounts of sleep prior to work are fundamental to improved performance and alertness in the workplace. In addition, planned naps taken during work maintain appropriate levels of waking function for both daytime and night-time work. Clearly, sufficient sleep after work is vital in promoting recovery from fatigue. Recent data also suggest that the time interval between shifts should be adjusted according to the biological timing of sleep. Although sleep is more likely to be replaced by job and other activities in the real life, research shows that it is worthwhile to revise the work schedules in order to optimize sleep before, sometime during and after the work period. Therefore, we suggest establishing work-sleep balance, similar to work-life balance, as a principle for designing and improving work schedules. PMID:22738292

  4. Prioritizing sleep for healthy work schedules

    Directory of Open Access Journals (Sweden)

    Takahashi Masaya

    2012-03-01

    Full Text Available Abstract Good sleep is advantageous to the quality of life. Sleep-related benefits are particularly helpful for the working class, since poor or inadequate amounts of sleep degrade work productivity and overall health. This review paper explores the essential role of sleep in healthy work schedules and primarily focuses on the timing of sleep in relation to the work period (that is, before, during and after work. Data from laboratory, field and modeling studies indicate that consistent amounts of sleep prior to work are fundamental to improved performance and alertness in the workplace. In addition, planned naps taken during work maintain appropriate levels of waking function for both daytime and night-time work. Clearly, sufficient sleep after work is vital in promoting recovery from fatigue. Recent data also suggest that the time interval between shifts should be adjusted according to the biological timing of sleep. Although sleep is more likely to be replaced by job and other activities in the real life, research shows that it is worthwhile to revise the work schedules in order to optimize sleep before, sometime during and after the work period. Therefore, we suggest establishing work-sleep balance, similar to work-life balance, as a principle for designing and improving work schedules.

  5. Prioritizing sleep for healthy work schedules.

    Science.gov (United States)

    Takahashi, Masaya

    2012-03-13

    Good sleep is advantageous to the quality of life. Sleep-related benefits are particularly helpful for the working class, since poor or inadequate amounts of sleep degrade work productivity and overall health. This review paper explores the essential role of sleep in healthy work schedules and primarily focuses on the timing of sleep in relation to the work period (that is, before, during and after work). Data from laboratory, field and modeling studies indicate that consistent amounts of sleep prior to work are fundamental to improved performance and alertness in the workplace. In addition, planned naps taken during work maintain appropriate levels of waking function for both daytime and night-time work. Clearly, sufficient sleep after work is vital in promoting recovery from fatigue. Recent data also suggest that the time interval between shifts should be adjusted according to the biological timing of sleep. Although sleep is more likely to be replaced by job and other activities in the real life, research shows that it is worthwhile to revise the work schedules in order to optimize sleep before, sometime during and after the work period. Therefore, we suggest establishing work-sleep balance, similar to work-life balance, as a principle for designing and improving work schedules.

  6. Evaluating irrigation scheduling of hydroponic tomato in Navarra, Spain

    NARCIS (Netherlands)

    Lizarraga, H.J.; Boesveld, H.; Huibers, F.P.; Robles, H.

    2003-01-01

    The correct supply of water and nutrients is important in hydroponic growing systems in order to use water efficiently, avoid stress situations, and control production. The present study was conducted to evaluate two irrigation scheduling techniques for hydroponic tomato production in Navarra,

  7. DESIGN OF A HYPERHEURISTIC FOR PRODUCTION SCHEDULING IN JOB SHOP ENVIRONMENTS DISEÑO DE UNA HIPERHEURISTICA PARA LA PROGRAMACION DE LA PRODUCCIÓN EN AMBIENTES JOB SHOP

    Directory of Open Access Journals (Sweden)

    Omar Danilo Castrillón

    2010-08-01

    Full Text Available The objective of the present work is to diminish the total process time (Makespan and to increase the machine process time, by diminishing the idle time in a job-shop environment. Through the design of a hyper-heuristic based on an ant colony and genetic algorithms. This work is developed in two phases: in the first phase, a hyper-heuristic identification and definition is carried out for sequencing processes in job shop environments. In the second phase, the system effectiveness in the traditional production programming is shown. In the investigation project, an enterprise from the metal mechanic sector was chosen, where by means of a combination of an ant colony and genetic algorithms, the optimal route for an order is scheduled, achieving the optimization or suboptimization of its respective total process time in an upper percentage of 95%.El objetivo del presente trabajo es disminuir el tiempo de proceso (Makespan e incrementar el tiempo de trabajo de las maquinas, diminuyendo el tiempo de ocio en ambientes de Job Shop, a través del diseño de una Hiper-heurística basada en colonia de hormigas y algoritmos genéticos. Este trabajo se desarrolla en dos etapas: en la primera se realiza la definición e identificación de una Hiper-heurística para la secuenciación de procesos en ambientes Job shop. En la segunda etapa, es mostrada la efectividad del sistema en la programación de la producción. En el proyecto de investigación, se seleccionó una empresa del sector metalmecánico, donde por medio de una combinación de colonia de hormigas y algoritmos genéticos, se programa la ruta óptima para un pedido, logrando la optimización o suboptimización de su respectivo tiempo total de proceso en un porcentaje superior al 95%.

  8. The role of romantic attraction and conflict resolution in predicting shorter and longer relationship maintenance among adolescents.

    Science.gov (United States)

    Appel, Israel; Shulman, Shmuel

    2015-04-01

    This study examined the role of romantic attraction and conflict resolution patterns in shorter and longer relationship maintenance among adolescent couples. Data were used from 55 couples aged 15-18 years. Partners completed the Romantic Attraction scale and were observed negotiating a disagreement. Three and 6 months later, they were asked to report whether they were still together. Findings indicated that partners' romantic attraction and the tendency to minimize disagreements during interaction predicted shorter relationship maintenance. In contrast, longer relationship maintenance was predicted by partners' capability to resolve conflicts constructively in a positive atmosphere. Findings are embedded and discussed within Fisher's (2004) evolutionary theory of love.

  9. Investigations of model polymers: Dynamics of melts and statics of a long chain in a dilute melt of shorter chains

    International Nuclear Information System (INIS)

    Bishop, M.; Ceperley, D.; Frisch, H.L.; Kalos, M.H.

    1982-01-01

    We report additional results on a simple model of polymers, namely the diffusion in concentrated polymer systems and the static properties of one long chain in a dilute melt of shorter chains. It is found, for the polymer sizes and time scales amenable to our computer calculations, that there is as yet no evidence for a ''reptation'' regime in a melt. There is some indication of reptation in the case of a single chain moving through fixed obstacles. No statistically significant effect of the change, from excluded volume behavior of the long chain to ideal behavior as the shorter chains grow, is observed

  10. NRC comprehensive records disposition schedule

    International Nuclear Information System (INIS)

    1983-05-01

    Effective January 1, 1982, NRC will institute records retention and disposal practives in accordance with the approved Comprehensive Records Disposition Schedule (CRDS). CRDS is comprised of NRC Schedules (NRCS) 1 to 4 which apply to the agency's program or substantive records and General Records Schedules (GRS) 1 to 24 which apply to housekeeping or facilitative records. NRCS-I applies to records common to all or most NRC offices; NRCS-II applies to program records as found in the various offices of the Commission, Atomic Safety and Licensing Board Panel, and the Atomic Safety and Licensing Appeal Panel; NRCS-III applies to records accumulated by the Advisory Committee on Reactor Safeguards; and NRCS-IV applies to records accumulated in the various NRC offices under the Executive Director for Operations. The schedules are assembled functionally/organizationally to facilitate their use. Preceding the records descriptions and disposition instructions for both NRCS and GRS, there are brief statements on the organizational units which accumulate the records in each functional area, and other information regarding the schedules' applicability

  11. Multiuser switched diversity scheduling schemes

    KAUST Repository

    Shaqfeh, Mohammad; Alnuweiri, Hussein M.; Alouini, Mohamed-Slim

    2012-01-01

    Multiuser switched-diversity scheduling schemes were recently proposed in order to overcome the heavy feedback requirements of conventional opportunistic scheduling schemes by applying a threshold-based, distributed, and ordered scheduling mechanism. The main idea behind these schemes is that slight reduction in the prospected multiuser diversity gains is an acceptable trade-off for great savings in terms of required channel-state-information feedback messages. In this work, we characterize the achievable rate region of multiuser switched diversity systems and compare it with the rate region of full feedback multiuser diversity systems. We propose also a novel proportional fair multiuser switched-based scheduling scheme and we demonstrate that it can be optimized using a practical and distributed method to obtain the feedback thresholds. We finally demonstrate by numerical examples that switched-diversity scheduling schemes operate within 0.3 bits/sec/Hz from the ultimate network capacity of full feedback systems in Rayleigh fading conditions. © 2012 IEEE.

  12. Sport Tournament Automated Scheduling System

    Directory of Open Access Journals (Sweden)

    Raof R. A. A

    2018-01-01

    Full Text Available The organizer of sport events often facing problems such as wrong calculations of marks and scores, as well as difficult to create a good and reliable schedule. Most of the time, the issues about the level of integrity of committee members and also issues about errors made by human came into the picture. Therefore, the development of sport tournament automated scheduling system is proposed. The system will be able to automatically generate the tournament schedule as well as automatically calculating the scores of each tournament. The problem of scheduling the matches of a round robin and knock-out phase in a sport league are given focus. The problem is defined formally and the computational complexity is being noted. A solution algorithm is presented using a two-step approach. The first step is the creation of a tournament pattern and is based on known graph-theoretic method. The second one is an assignment problem and it is solved using a constraint based depth-first branch and bound procedure that assigns actual teams to numbers in the pattern. As a result, the scheduling process and knock down phase become easy for the tournament organizer and at the same time increasing the level of reliability.

  13. Multiuser switched diversity scheduling schemes

    KAUST Repository

    Shaqfeh, Mohammad

    2012-09-01

    Multiuser switched-diversity scheduling schemes were recently proposed in order to overcome the heavy feedback requirements of conventional opportunistic scheduling schemes by applying a threshold-based, distributed, and ordered scheduling mechanism. The main idea behind these schemes is that slight reduction in the prospected multiuser diversity gains is an acceptable trade-off for great savings in terms of required channel-state-information feedback messages. In this work, we characterize the achievable rate region of multiuser switched diversity systems and compare it with the rate region of full feedback multiuser diversity systems. We propose also a novel proportional fair multiuser switched-based scheduling scheme and we demonstrate that it can be optimized using a practical and distributed method to obtain the feedback thresholds. We finally demonstrate by numerical examples that switched-diversity scheduling schemes operate within 0.3 bits/sec/Hz from the ultimate network capacity of full feedback systems in Rayleigh fading conditions. © 2012 IEEE.

  14. Environmental surveillance master sampling schedule

    International Nuclear Information System (INIS)

    Bisping, L.E.

    1991-01-01

    Environmental surveillance of the Hanford Site and surrounding areas is conducted by the Pacific Northwest Laboratory (PNL) for the US Department of Energy (DOE). This document contains the planned schedule for routine sample collection for the Surface Environmental Surveillance Project (SESP) and Ground-Water Monitoring Project. The routine sampling plan for the SESP has been revised this year to reflect changing site operations and priorities. Some sampling previously performed at least annually has been reduced in frequency, and some new sampling to be performed at a less than annual frequency has been added. Therefore, the SESP schedule reflects sampling to be conducted in calendar year 1991 as well as future years. The ground-water sampling schedule is for 1991. This schedule is subject to modification during the year in response to changes in Site operation, program requirements, and the nature of the observed results. Operational limitations such as weather, mechanical failures, sample availability, etc., may also require schedule modifications. Changes will be documented in the respective project files, but this plan will not be reissued. The purpose of these monitoring projects is to evaluate levels of radioactive and nonradioactive pollutants in the Hanford evirons

  15. Environmental surveillance master sampling schedule

    Energy Technology Data Exchange (ETDEWEB)

    Bisping, L.E.

    1991-01-01

    Environmental surveillance of the Hanford Site and surrounding areas is conducted by the Pacific Northwest Laboratory (PNL) for the US Department of Energy (DOE). This document contains the planned schedule for routine sample collection for the Surface Environmental Surveillance Project (SESP) and Ground-Water Monitoring Project. The routine sampling plan for the SESP has been revised this year to reflect changing site operations and priorities. Some sampling previously performed at least annually has been reduced in frequency, and some new sampling to be performed at a less than annual frequency has been added. Therefore, the SESP schedule reflects sampling to be conducted in calendar year 1991 as well as future years. The ground-water sampling schedule is for 1991. This schedule is subject to modification during the year in response to changes in Site operation, program requirements, and the nature of the observed results. Operational limitations such as weather, mechanical failures, sample availability, etc., may also require schedule modifications. Changes will be documented in the respective project files, but this plan will not be reissued. The purpose of these monitoring projects is to evaluate levels of radioactive and nonradioactive pollutants in the Hanford evirons.

  16. Mixed Criticality Scheduling for Industrial Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Xi Jin

    2016-08-01

    Full Text Available Wireless sensor networks (WSNs have been widely used in industrial systems. Their real-time performance and reliability are fundamental to industrial production. Many works have studied the two aspects, but only focus on single criticality WSNs. Mixed criticality requirements exist in many advanced applications in which different data flows have different levels of importance (or criticality. In this paper, first, we propose a scheduling algorithm, which guarantees the real-time performance and reliability requirements of data flows with different levels of criticality. The algorithm supports centralized optimization and adaptive adjustment. It is able to improve both the scheduling performance and flexibility. Then, we provide the schedulability test through rigorous theoretical analysis. We conduct extensive simulations, and the results demonstrate that the proposed scheduling algorithm and analysis significantly outperform existing ones.

  17. SIMULTANEOUS SCHEDULING AND OPERATIONAL OPTIMIZATION OF MULTIPRODUCT, CYCLIC CONTINUOUS PLANTS

    Directory of Open Access Journals (Sweden)

    A. Alle

    2002-03-01

    Full Text Available The problems of scheduling and optimization of operational conditions in multistage, multiproduct continuous plants with intermediate storage are simultaneously addressed. An MINLP model, called TSPFLOW, which is based on the TSP formulation for product sequencing, is proposed to schedule the operation of such plants. TSPFLOW yields a one-order-of-magnitude CPU time reduction as well as the solution of instances larger than those formerly reported (Pinto and Grossmann, 1994. Secondly, processing rates and yields are introduced as additional optimization variables in order to state the simultaneous problem of scheduling with operational optimization. Results show that trade-offs are very complex and that the development of a straightforward (rule of thumb method to optimally schedule the operation is less effective than the proposed approach.

  18. SIMULTANEOUS SCHEDULING AND OPERATIONAL OPTIMIZATION OF MULTIPRODUCT, CYCLIC CONTINUOUS PLANTS

    Directory of Open Access Journals (Sweden)

    Alle A.

    2002-01-01

    Full Text Available The problems of scheduling and optimization of operational conditions in multistage, multiproduct continuous plants with intermediate storage are simultaneously addressed. An MINLP model, called TSPFLOW, which is based on the TSP formulation for product sequencing, is proposed to schedule the operation of such plants. TSPFLOW yields a one-order-of-magnitude CPU time reduction as well as the solution of instances larger than those formerly reported (Pinto and Grossmann, 1994. Secondly, processing rates and yields are introduced as additional optimization variables in order to state the simultaneous problem of scheduling with operational optimization. Results show that trade-offs are very complex and that the development of a straightforward (rule of thumb method to optimally schedule the operation is less effective than the proposed approach.

  19. Car painting process scheduling with harmony search algorithm

    Science.gov (United States)

    Syahputra, M. F.; Maiyasya, A.; Purnamawati, S.; Abdullah, D.; Albra, W.; Heikal, M.; Abdurrahman, A.; Khaddafi, M.

    2018-02-01

    Automotive painting program in the process of painting the car body by using robot power, making efficiency in the production system. Production system will be more efficient if pay attention to scheduling of car order which will be done by considering painting body shape of car. Flow shop scheduling is a scheduling model in which the job-job to be processed entirely flows in the same product direction / path. Scheduling problems often arise if there are n jobs to be processed on the machine, which must be specified which must be done first and how to allocate jobs on the machine to obtain a scheduled production process. Harmony Search Algorithm is a metaheuristic optimization algorithm based on music. The algorithm is inspired by observations that lead to music in search of perfect harmony. This musical harmony is in line to find optimal in the optimization process. Based on the tests that have been done, obtained the optimal car sequence with minimum makespan value.

  20. Scheduled evening sleep and enhanced lighting improve adaptation to night shift work in older adults.

    Science.gov (United States)

    Chinoy, Evan D; Harris, Michael P; Kim, Min Ju; Wang, Wei; Duffy, Jeanne F

    2016-12-01

    We tested whether a sleep and circadian-based treatment shown to improve circadian adaptation to night shifts and attenuate negative effects on alertness, performance and sleep in young adults would also be effective in older adults. We assessed subjective alertness, sustained attention (psychomotor vigilance task, PVT), sleep duration (actigraphy) and circadian timing (salivary dim-light melatonin onset, DLMO) in 18 older adults (57.2±3.8 years; mean±SD) in a simulated shift work protocol. 4 day shifts were followed by 3 night shifts in the laboratory. Participants slept at home and were randomised to either the treatment group (scheduled evening sleep and enhanced lighting during the latter half of night shifts) or control group (ad-lib sleep and typical lighting during night shifts). Compared with day shifts, alertness and sustained attention declined on the first night shift in both groups, and was worse in the latter half of the night shifts. Alertness and attention improved on nights 2 and 3 for the treatment group but remained lower for the control group. Sleep duration in the treatment group remained similar to baseline (6-7 hours) following night shifts, but was shorter (3-5 hours) following night shifts in the control group. Treatment group circadian timing advanced by 169.3±16.1 min (mean±SEM) but did not shift (-9.7±9.9 min) in the control group. The combined treatment of scheduled evening sleep and enhanced lighting increased sleep duration and partially aligned circadian phase with sleep and work timing, resulting in improved night shift alertness and performance. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  1. Designing scheduling concept and computer support in the food processing industries

    NARCIS (Netherlands)

    van Donk, DP; van Wezel, W; Gaalman, G; Bititci, US; Carrie, AS

    1998-01-01

    Food processing industries cope with a specific production process and a dynamic market. Scheduling the production process is thus important in being competitive. This paper proposes a hierarchical concept for structuring the scheduling and describes the (computer) support needed for this concept.

  2. Schedulability Analysis for Java Finalizers

    DEFF Research Database (Denmark)

    Bøgholm, Thomas; Hansen, Rene Rydhof; Søndergaard, Hans

    2010-01-01

    Java finalizers perform clean-up and finalisation of objects at garbage collection time. In real-time Java profiles the use of finalizers is either discouraged (RTSJ, Ravenscar Java) or even disallowed (JSR-302), mainly because of the unpredictability of finalizers and in particular their impact...... on the schedulability analysis. In this paper we show that a controlled scoped memory model results in a structured and predictable execution of finalizers, more reminiscent of C++ destructors than Java finalizers. Furthermore, we incorporate finalizers into a (conservative) schedulability analysis for Predictable Java...... programs. Finally, we extend the SARTS tool for automated schedulability analysis of Java bytecode programs to handle finalizers in a fully automated way....

  3. Environmental surveillance master sampling schedule

    International Nuclear Information System (INIS)

    Bisping, L.E.

    1997-01-01

    Environmental surveillance of the Hanford Site and surrounding areas is conducted by the Pacific Northwest National Laboratory (PNNL)(a) for the US Department of Energy (DOE). This document contains the planned 1997 schedules for routine collection of samples for the Surface Environmental Surveillance Project (SESP) and Drinking Water Monitoring Project. In addition, Section 3.0, Biota, also reflects a rotating collection schedule identifying the year a specific sample is scheduled for collection. The purpose of these monitoring projects is to evaluate levels of radioactive and nonradioactive pollutants in the Hanford environs, as required in DOE Order 5400.1, General Environmental Protection Program, and DOE Order 5400.5, Radiation Protection of the Public and the Environment. The sampling methods will be the same as those described in the Environmental Monitoring Plan, US Department of Energy, Richland Operations Office, DOE/RL91-50, Rev. 1, US Department of Energy, Richland, Washington

  4. Schedules for Regulatory Regimes

    International Nuclear Information System (INIS)

    Austvik, Ole Gunnar

    2003-01-01

    The idea of regulating transporters' terms of operations is that if the market itself does not produce optimal outcomes, then it can be mimicked to do so through regulatory and other public instruments. The first-best solution could be a subsidized (publicly owned) enterprise that sets tariffs according to marginal costs. This has been the tradition in many European countries in the aftermath of WW2. Due to lack of innovative pressure on and x-inefficiency in these companies, this solution is today viewed as inferior to the system of regulating independent (privately owned) firms. When the European gas market becomes liberalized, part of the process in many countries is to (partially) privatise the transport utilities. Privatised or not, in a liberalized market, the transport utilities should face an independent authority that overviews their operations not only in technical, but also in economic terms. Under regulation, a ''visible hand'' is introduced to correct the imperfect market's ''invisible hand''. By regulating the framework and conditions for how firms may operate, public authorities seek to achieve what is considered optimal for the society. The incentives and disincentives given for pricing and production should create mechanisms leading to an efficient allocation of resources and ''acceptable'' distribution of income. As part of intervening into firms' behavior, regulation may be introduced to direct the firm to behave in certain ways. The framework and regulatory mechanisms for the market must then be constructed in a way that companies voluntarily produce an amount at a price that gives maximal profits and simultaneously satisfies social goals. The regulations should lead to consistency between the company's desire to maximize profits and the society's desire for maximizing welfare, as in a perfectly competitive market. This is the core of regulatory economics

  5. Endogenous scheduling preferences and congestion

    DEFF Research Database (Denmark)

    Fosgerau, Mogens; Small, Kenneth

    2010-01-01

    and leisure, but agglomeration economies at home and at work lead to scheduling preferences forming endogenously. Using bottleneck congestion technology, we obtain an equilibrium queuing pattern consistent with a general version of the Vickrey bottleneck model. However, the policy implications are different....... Compared to the predictions of an analyst observing untolled equilibrium and taking scheduling preferences as exogenous, we find that both the optimal capacity and the marginal external cost of congestion have changed. The benefits of tolling are greater, and the optimal time varying toll is different....

  6. Travel time and concurrent-schedule choice: retrospective versus prospective control.

    OpenAIRE

    Davison, M; Elliffe, D

    2000-01-01

    Six pigeons were trained on concurrent variable-interval schedules in which two different travel times between alternatives, 4.5 and 0.5 s, were randomly arranged. In Part 1, the next travel time was signaled while the subjects were responding on each alternative. Generalized matching analyses of performance in the presence of the two travel-time signals showed significantly higher response and time sensitivity when the longer travel time was signaled compared to when the shorter time was sig...

  7. Artificial intelligence approaches to astronomical observation scheduling

    Science.gov (United States)

    Johnston, Mark D.; Miller, Glenn

    1988-01-01

    Automated scheduling will play an increasing role in future ground- and space-based observatory operations. Due to the complexity of the problem, artificial intelligence technology currently offers the greatest potential for the development of scheduling tools with sufficient power and flexibility to handle realistic scheduling situations. Summarized here are the main features of the observatory scheduling problem, how artificial intelligence (AI) techniques can be applied, and recent progress in AI scheduling for Hubble Space Telescope.

  8. Lifetime Improvement by Battery Scheduling

    NARCIS (Netherlands)

    Jongerden, M.R.; Schmitt, Jens B.; Haverkort, Boudewijn R.H.M.

    The use of mobile devices is often limited by the lifetime of their batteries. For devices that have multiple batteries or that have the option to connect an extra battery, battery scheduling, thereby exploiting the recovery properties of the batteries, can help to extend the system lifetime. Due to

  9. Lifetime improvement by battery scheduling

    NARCIS (Netherlands)

    Jongerden, M.R.; Haverkort, Boudewijn R.H.M.

    The use of mobile devices is often limited by the lifetime of its battery. For devices that have multiple batteries or that have the option to connect an extra battery, battery scheduling, thereby exploiting the recovery properties of the batteries, can help to extend the system lifetime. Due to the

  10. How useful are preemptive schedules?

    NARCIS (Netherlands)

    Brucker, P.; Heitmann, S.; Hurink, J.L.

    2001-01-01

    Machine scheduling admits two options to process jobs. In a preemptive mode processing may be interrupted and resumed later even on a different machine. In a nonpreemptive mode interruptions are not allowed. Usually, the possibility to preempt jobs leads to better performance values. However, also

  11. Interaction in activity location scheduling

    NARCIS (Netherlands)

    Tabak, V.; Vries, de B.; Dijkstra, J.; Jessurun, A.J.

    2006-01-01

    In this paper we discuss the interaction in activity location scheduling which is the main subject of an ongoing research project called "User Simulation of Space Utilization". The aim of this research project is to develop an overall model for the simulation of human movement and utilization of

  12. Scheduling with target start times

    NARCIS (Netherlands)

    Hoogeveen, J.A.; Velde, van de S.L.; Klein Haneveld, W.K.; Vrieze, O.J.; Kallenberg, L.C.M.

    1997-01-01

    We address the single-machine problem of scheduling n independent jobs subject to target start times. Target start times are essentially release times that may be violated at a certain cost. The goal is to minimize an objective function that is composed of total completion time and maximum

  13. Stochastic scheduling on unrelated machines

    NARCIS (Netherlands)

    Skutella, Martin; Sviridenko, Maxim; Uetz, Marc Jochen

    2013-01-01

    Two important characteristics encountered in many real-world scheduling problems are heterogeneous machines/processors and a certain degree of uncertainty about the actual sizes of jobs. The first characteristic entails machine dependent processing times of jobs and is captured by the classical

  14. Flexible Schedules and Shift Work.

    Science.gov (United States)

    Beers, Thomas M.

    2000-01-01

    Flexible work hours have gained prominence, as more than 25 million workers (27.6% of all full-time workers) can now vary their schedules. However, there has been little change since the mid-1980s in the proportion who work a shift other than a regular daytime shift. (JOW)

  15. Scheduling periodic tasks with slack

    NARCIS (Netherlands)

    Korst, J.H.M.; Aarts, E.H.L.; Lenstra, J.K.

    1997-01-01

    We consider the problem of nonpreemptively scheduling periodic tasks on a minimum number of identical processors, assuming that some slack is allowed in the time between successive executions of a periodic task. We prove that the problem is NP-hard in the strong sense. Necessary and sufficient

  16. Toward Realistic Acquisition Schedule Estimates

    Science.gov (United States)

    2016-04-30

    replace earlier versions of the F/A-18. Joint and International Nature At the time of JSF conception, there was a clear preference at the highest levels...ALPHABET SOUP ” (Aboulafia, 2015) OF STUDIES AND CONCEPTS • … MERGED INTO JAST • … WHICH EVOLVED TO JSF • WELL-KNOWN COST AND SCHEDULE

  17. Analyzing NPS Scheduling Using OSIRIS

    Science.gov (United States)

    1993-03-01

    School TEACHER SCHEDULE BLOCKS REPORT Date: 2/19/93 Period Name ID Term Days 1234 Adragna , Joe 170401 1 F xx Agrawal, Brij 120101 1 F xx Almquist...LOAD REPORT Date: 3/18/93 Total Max Consec Total Teacher ID Term Classes Classes Stud Adragna , Joe 170401 1 1 1 3 Agrawal, Brij 120101 1 2 2 98 Aiello

  18. 15 CFR 714.1 - Annual declaration requirements for plant sites that produce a Schedule 3 chemical in excess of...

    Science.gov (United States)

    2010-01-01

    ... plant sites that produce a Schedule 3 chemical in excess of 30 metric tons. 714.1 Section 714.1 Commerce... SCHEDULE 3 CHEMICALS § 714.1 Annual declaration requirements for plant sites that produce a Schedule 3... in the production of a chemical in any units within the same plant through chemical reaction...

  19. Implementation Learning and Forgetting Curve to Scheduling in Garment Industry

    Science.gov (United States)

    Muhamad Badri, Huda; Deros, Baba Md; Syahri, M.; Saleh, Chairul; Fitria, Aninda

    2016-02-01

    The learning curve shows the relationship between time and the cumulative number of units produced which using the mathematical description on the performance of workers in performing repetitive works. The problems of this study is level differences in the labors performance before and after the break which affects the company's production scheduling. The study was conducted in the garment industry, which the aims is to predict the company production scheduling using the learning curve and forgetting curve. By implementing the learning curve and forgetting curve, this paper contributes in improving the labors performance that is in line with the increase in maximum output 3 hours productive before the break are 15 unit product with learning curve percentage in the company is 93.24%. Meanwhile, the forgetting curve improving maximum output 3 hours productive after the break are 11 unit product with the percentage of forgetting curve in the company is 92.96%. Then, the obtained 26 units product on the productive hours one working day is used as the basic for production scheduling.

  20. Flexible job-shop scheduling based on genetic algorithm and simulation validation

    Directory of Open Access Journals (Sweden)

    Zhou Erming

    2017-01-01

    Full Text Available This paper selects flexible job-shop scheduling problem as the research object, and Constructs mathematical model aimed at minimizing the maximum makespan. Taking the transmission reverse gear production line of a transmission corporation as an example, genetic algorithm is applied for flexible jobshop scheduling problem to get the specific optimal scheduling results with MATLAB. DELMIA/QUEST based on 3D discrete event simulation is applied to construct the physical model of the production workshop. On the basis of the optimal scheduling results, the logical link of the physical model for the production workshop is established, besides, importing the appropriate process parameters to make virtual simulation on the production workshop. Finally, through analyzing the simulated results, it shows that the scheduling results are effective and reasonable.

  1. Development of Watch Schedule Using Rules Approach

    Science.gov (United States)

    Jurkevicius, Darius; Vasilecas, Olegas

    The software for schedule creation and optimization solves a difficult, important and practical problem. The proposed solution is an online employee portal where administrator users can create and manage watch schedules and employee requests. Each employee can login with his/her own account and see his/her assignments, manage requests, etc. Employees set as administrators can perform the employee scheduling online, manage requests, etc. This scheduling software allows users not only to see the initial and optimized watch schedule in a simple and understandable form, but also to create special rules and criteria and input their business. The system using rules automatically will generate watch schedule.

  2. Project management with dynamic scheduling baseline scheduling, risk analysis and project control

    CERN Document Server

    Vanhoucke, Mario

    2013-01-01

    The topic of this book is known as dynamic scheduling, and is used to refer to three dimensions of project management and scheduling: the construction of a baseline schedule and the analysis of a project schedule's risk as preparation of the project control phase during project progress. This dynamic scheduling point of view implicitly assumes that the usability of a project's baseline schedule is rather limited and only acts as a point of reference in the project life cycle.

  3. Using Irrigation Scheduling to Increase Water Productivity of Wheat-Maize Rotation under Climate Change Conditions Calendario de Riego para Aumentar la Productividad del Agua en Rotación Trigo-Maíz en Condiciones de Cambio Climático

    Directory of Open Access Journals (Sweden)

    Gamal El Afandi

    2010-09-01

    Full Text Available Irrigation scheduling was used to increase water productivity of wheat (Triticum aestivum L.-maize (Zea mays L. rotation under two climate change scenarios. Three wheat varieties and two maize hybrids were planted at in a 2-yr field experiment. CropSyst model was calibrated and validated for the collected field data, then was used to assess the impact of two climate change scenarios (A2 and B2 and three adaptation strategies (early sowing changing, irrigation schedule and the interaction between them in the year of 2038s. The results revealed that A2 reduced yield more than B2 scenario for both crops. High yield reduction in wheat-maize rotation could be expected under climate change conditions, where wheat and maize yield will be reduced by an average of 41 and 56%, respectively. The most effective adaptation strategy for wheat was sowing 3 wk earlier and irrigation every 21 d, with irrigation water saving and no yield improvement under A2 scenario in both growing seasons. Whereas under B2 scenario yield improvement by 2% occurred with 3% saving in the applied irrigation water in the 1st growing season and in the 2nd growing season yield could improved by 8% with less than 1% increase in the applied irrigation water and higher water productivity. Changing irrigation schedule was an effective adaptation option for maize, where yield improvement could occur under both climate change scenarios in both growing seasons by up to 9% with less than 3% increase in the applied irrigation water and higher water productivity.

  4. The Vessel Schedule Recovery Problem

    DEFF Research Database (Denmark)

    Brouer, Berit Dangaard; Plum, Christian Edinger Munk; Vaaben, Bo

    Maritime transportation is the backbone of world trade and is accountable for around 3% of the worlds CO2 emissions. We present the Vessel Schedule Recovery Problem (VSRP) to evaluate a given disruption scenario and to select a recovery action balancing the trade off between increased bunker cons...... consumption and the impact on the remaining network and the customer service level. The model is applied to 4 real cases from Maersk Line. Solutions are comparable or superior to those chosen by operations managers. Cost savings of up to 58% may be achieved.......Maritime transportation is the backbone of world trade and is accountable for around 3% of the worlds CO2 emissions. We present the Vessel Schedule Recovery Problem (VSRP) to evaluate a given disruption scenario and to select a recovery action balancing the trade off between increased bunker...

  5. CMS Planning and Scheduling System

    CERN Document Server

    Kotamaki, M

    1998-01-01

    The paper describes the procedures and the system to build and maintain the schedules needed to manage time, resources, and progress of the CMS project. The system is based on the decomposition of the project into work packages, which can be each considered as a complete project with its own structure. The system promotes the distribution of the decision making and responsibilities to lower levels in the organisation by providing a state-of-the-art system to formalise the external commitments of the work packages without limiting their ability to modify their internal schedules to best meet their commitments. The system lets the project management focus on the interfaces between the work packages and alerts the management immediately if a conflict arises. The proposed system simplifies the planning and management process and eliminates the need for a large, centralised project management system.

  6. Irrigation scheduling research: South African experiences and future ...

    African Journals Online (AJOL)

    This paper was originally presented at the Water Research. Commission 40-Year .... direct link with dry matter production (Tanner and Sinclair,. 1983). Scheduling ..... type infrared thermometer for measuring canopy temperature received much ..... subscribers and advice was made available through web down- loads for ...

  7. 9 CFR 381.37 - Schedule of operations.

    Science.gov (United States)

    2010-01-01

    ... Holiday Service; Billing Establishments § 381.37 Schedule of operations. (a) No operations requiring inspection shall be conducted except under the supervision of an Inspection Service employee. All... 381.37 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  8. 42 CFR 7.4 - Schedule of charges.

    Science.gov (United States)

    2010-10-01

    ... REFERENCE BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.4 Schedule of charges. The charges imposed in... ingredients. Charges may vary over time and between different biological standards or biological preparations... is available from the Biological Products Branch, Center for Infectious Diseases, Centers for Disease...

  9. 75 FR 42831 - Proposed Collection; Comment Request for Form 1065, Schedule C, Schedule D, Schedule K-1...

    Science.gov (United States)

    2010-07-22

    .../or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law... Income, Credits, Deductions and Other Items), Schedule L (Balance Sheets per Books), Schedule M-1 (Reconciliation of Income (Loss) per Books With Income (Loss) per Return)), Schedule M-2 (Analysis of Partners...

  10. Concurrent schedules of wheel-running reinforcement: choice between different durations of opportunity to run in rats.

    Science.gov (United States)

    Belke, Terry W

    2006-02-01

    How do animals choose between opportunities to run of different durations? Are longer durations preferred over shorter durations because they permit a greater number of revolutions? Are shorter durations preferred because they engender higher rates of running? Will longer durations be chosen because running is less constrained? The present study reports on three experiments that attempted to address these questions. In the first experiment, five male Wistar rats chose between 10-sec and 50-sec opportunities to run on modified concurrent variable-interval (VI) schedules. Across conditions, the durations associated with the alternatives were reversed. Response, time, and reinforcer proportions did not vary from indifference. In a second experiment, eight female Long-Evans rats chose between opportunities to run of equal (30 sec) and unequal durations (10 sec and 50 sec) on concurrent variable-ratio (VR) schedules. As in Experiment 1, between presentations of equal duration conditions, 10-sec and 50-sec durations were reversed. Results showed that response, time, and reinforcer proportions on an alternative did not vary with reinforcer duration. In a third experiment, using concurrent VR schedules, durations were systematically varied to decrease the shorter duration toward 0 sec. As the shorter duration decreased, response, time, and reinforcer proportions shifted toward the longer duration. In summary, differences in durations of opportunities to run did not affect choice behavior in a manner consistent with the assumption that a longer reinforcer is a larger reinforcer.

  11. Preemptive scheduling in overloaded systems

    Czech Academy of Sciences Publication Activity Database

    Chrobak, M.; Epstein, L.; Noga, J.; Sgall, Jiří; van Stee, R.; Tichý, Tomáš; Vakhania, N.

    2003-01-01

    Roč. 67, č. 1 (2003), s. 183-197 ISSN 0022-0000 R&D Projects: GA ČR GA201/01/1195; GA MŠk ME 476; GA AV ČR IAA1019901; GA MŠk LN00A056 Institutional research plan: CEZ:AV0Z1019905; CEZ:AV0Z1019905 Keywords : scheduling * online algorithms * benefit Subject RIV: BA - General Mathematics Impact factor: 0.795, year: 2003

  12. WCET Analysis for Preemptive Scheduling

    OpenAIRE

    Altmeyer, Sebastian; Gebhard, Gernot

    2008-01-01

    Hard real-time systems induce strict constraints on the timing of the task set. Validation of these timing constraints is thus a major challenge during the design of such a system. Whereas the derivation of timing guarantees must already be considered complex if tasks are running to completion, it gets even more complex if tasks are scheduled preemptively -- especially due to caches, deployed to improve the average performance. In this paper we propose a new method to compu...

  13. Scheduling Maintenance Jobs in Networks

    OpenAIRE

    Abed, Fidaa; Chen, Lin; Disser, Yann; Groß, Martin; Megow, Nicole; Meißner, Julie; Richter, Alexander T.; Rischke, Roman

    2017-01-01

    We investigate the problem of scheduling the maintenance of edges in a network, motivated by the goal of minimizing outages in transportation or telecommunication networks. We focus on maintaining connectivity between two nodes over time; for the special case of path networks, this is related to the problem of minimizing the busy time of machines. We show that the problem can be solved in polynomial time in arbitrary networks if preemption is allowed. If preemption is restricted to integral t...

  14. Broadcast scheduling for mobile advertising

    OpenAIRE

    De Reyck, B.; Degraeve, Z.

    2003-01-01

    We describe a broadcast scheduling system developed for a precision marketing firm specialized in location-sensitive permission-based mobile advertising using SMS (Short Message Service) text messaging. Text messages containing advertisements were sent to registered customers when they were shopping in one of two shopping centers in the vicinity of London. The ads typically contained a limited-time promotional offer. The company's problem was deciding which ads to send out to which customers ...

  15. Schedule of the nuclear program

    International Nuclear Information System (INIS)

    Heigl, F.

    1977-01-01

    The lecure tries to explain the main phases which must be passed to establish nuclear power plants, the feasibility phase, preconstruction and construction phase. Each phase consists of a lot of activities which are commented. Further the lecture tries to give some ideas of durances and dependence between the phases or activities to get a complete time schedule of the realization of a nuclear power project. (HP) [de

  16. Guidelines of Decommissioning Schedule Establishment

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Jae Yong; Yun, Taesik; Kim, Younggook; Kim, Hee-Geun [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    Decommissioning has recently become an issue highlighted in Korea due to the Permanent Shutdown (PS) of Kori-1 plant. Since Korea Hydro and Nuclear Power (KHNP) Company decided the PS of Kori-1 instead of further continued operation, Kori-1 will be the first decommissioning plant of the commercial reactors in Korea. Korean regulatory authority demands Initial Decommissioning Plan (IDP) for all the plants in operation and under construction. In addition, decommissioning should be considered for the completion of the life cycle of NPPs. To date, Korea has no experience regarding decommissioning of the commercial reactor and a lot of uncertainties will be expected due to its site-specific factors. However, optimized decommissioning process schedule must be indispensable in the safety and economic efficiency of the project. Differed from USA, Korea has no experience and know-hows of the operation and site management for decommissioning. Hence, in Korea, establishment of decommissioning schedule has to give more weight to safety than precedent cases. More economical and rational schedule will be composed by collecting and analyzing the experience data and site-specific data and information as the decommissioning progresses. In a long-range outlook, KHNP having capability of NPP decommissioning will try to decommissioning business in Korea and foreign countries.

  17. Shiftwork Scheduling for the 1990s.

    Science.gov (United States)

    Coleman, Richard M.

    1989-01-01

    The author discusses the problems of scheduling shift work, touching on such topics as employee desires, health requirements, and business needs. He presents a method for developing shift schedules that addresses these three areas. Implementation hints are also provided. (CH)

  18. Robust and Flexible Scheduling with Evolutionary Computation

    DEFF Research Database (Denmark)

    Jensen, Mikkel T.

    Over the last ten years, there have been numerous applications of evolutionary algorithms to a variety of scheduling problems. Like most other research on heuristic scheduling, the primary aim of the research has been on deterministic formulations of the problems. This is in contrast to real world...... scheduling problems which are usually not deterministic. Usually at the time the schedule is made some information about the problem and processing environment is available, but this information is uncertain and likely to change during schedule execution. Changes frequently encountered in scheduling...... environments include machine breakdowns, uncertain processing times, workers getting sick, materials being delayed and the appearance of new jobs. These possible environmental changes mean that a schedule which was optimal for the information available at the time of scheduling can end up being highly...

  19. Pittsburgh International Airport - Scheduled Passenger Traffic

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Here you can find Pittsburgh International Airport’s Monthly Scheduled Traffic Reports. Each of these reports contain a year-over-year (YOY) analysis of scheduled...

  20. DME Prosthetics Orthotics, and Supplies Fee Schedule

    Data.gov (United States)

    U.S. Department of Health & Human Services — Durable Medical Equipment, Prosthetics-Orthotics, and Supplies Fee Schedule. The list contains the fee schedule amounts, floors, and ceilings for all procedure codes...

  1. GSA eLibrary Schedules and Contracts

    Data.gov (United States)

    General Services Administration — GSA eLibrary (formerly Schedules e-Library) is the online source for the latest contract award information for: GSA Schedules; Department of Veterans Affairs (VA)...

  2. Interactive Anticipatory Scheduling for Two Military Applications

    National Research Council Canada - National Science Library

    Howe, Adele

    2003-01-01

    ...; these models partially explain what makes some job shop scheduling problems difficult. For the second, several algorithms for Air Force Satellite Control Network scheduling have been compared on historical and recent data...

  3. How should periods without social interaction be scheduled? Children's preference for practical schedules of positive reinforcement.

    Science.gov (United States)

    Luczynski, Kevin C; Hanley, Gregory P

    2014-01-01

    Several studies have shown that children prefer contingent reinforcement (CR) rather than yoked noncontingent reinforcement (NCR) when continuous reinforcement is programmed in the CR schedule. Preference has not, however, been evaluated for practical schedules that involve CR. In Study 1, we assessed 5 children's preference for obtaining social interaction via a multiple schedule (periods of fixed-ratio 1 reinforcement alternating with periods of extinction), a briefly signaled delayed reinforcement schedule, and an NCR schedule. The multiple schedule promoted the most efficient level of responding. In general, children chose to experience the multiple schedule and avoided the delay and NCR schedules, indicating that they preferred multiple schedules as the means to arrange practical schedules of social interaction. In Study 2, we evaluated potential controlling variables that influenced 1 child's preference for the multiple schedule and found that the strong positive contingency was the primary variable. © Society for the Experimental Analysis of Behavior.

  4. A Comparison of the DISASTER (Trademark) Scheduling Software with a Simultaneous Scheduling Algorithm for Minimizing Maximum Tardiness in Job Shops

    Science.gov (United States)

    1993-09-01

    goal ( Heizer , Render , and Stair, 1993:94). Integer Prgronmming. Integer programming is a general purpose approach used to optimally solve job shop...Scheduling," Operations Research Journal. 29, No 4: 646-667 (July-August 1981). Heizer , Jay, Barry Render and Ralph M. Stair, Jr. Production and Operations

  5. Network scheduling at Belene NPP construction site

    International Nuclear Information System (INIS)

    Matveev, A.

    2010-01-01

    Four types of schedules differing in the level of their detail are singled out to enhance the efficiency of Belene NPP Project implementation planning and monitoring: Level 1 Schedule–Summary Integrated Overall Time Schedule (SIOTS) is an appendix to EPC Contract. The main purpose of SIOTS is the large scale presentation of the current information on the Project implementation. Level 2 Schedule–Integrated Overall Time Schedule (IOTS)is the contract schedule for the Contractor (ASE JSC) and their subcontractors.The principal purpose of IOTS is the work progress planning and monitoring, the analysis of the effect of activities implementation upon the progress of the Project as a whole. IOTS is the reporting schedule at the Employer –Contractor level. Level 3 Schedules, Detail Time Schedules(DTS) are developed by those who actually perform the work and are agreed upon with Atomstroyexport JSC.The main purpose of DTS is the detail planning of Atomstroyexport subcontractor's activities. DTSare the reporting schedules at the level of Contractor-Subcontractor. Level 4 Schedules are the High Detail Time Schedules (HDTS), which are the day-to-day plans of work implementation and are developed, as a rule, for a week's time period.Each lower level time schedule details the activities of the higher level time schedule

  6. Vehicle and driver scheduling for public transit.

    Science.gov (United States)

    2009-08-01

    The problem of driver scheduling involves the construction of a legal set of shifts, including allowance : of overtime, which cover the blocks in a particular vehicle schedule. A shift is the work scheduled to be performed by : a driver in one day, w...

  7. An improved scheduling algorithm for linear networks

    KAUST Repository

    Bader, Ahmed; Alouini, Mohamed-Slim; Ayadi, Yassin

    2017-01-01

    In accordance with the present disclosure, embodiments of an exemplary scheduling controller module or device implement an improved scheduling process such that the targeted reduction in schedule length can be achieve while incurring minimal energy penalty by allowing for a large rate (or duration) selection alphabet.

  8. 40 CFR 141.702 - Sampling schedules.

    Science.gov (United States)

    2010-07-01

    ... serving at least 10,000 people must submit their sampling schedule for the initial round of source water... submitting the sampling schedule that EPA approves. (3) Systems serving fewer than 10,000 people must submit... analytical result for a scheduled sampling date due to equipment failure, loss of or damage to the sample...

  9. An improved scheduling algorithm for linear networks

    KAUST Repository

    Bader, Ahmed

    2017-02-09

    In accordance with the present disclosure, embodiments of an exemplary scheduling controller module or device implement an improved scheduling process such that the targeted reduction in schedule length can be achieve while incurring minimal energy penalty by allowing for a large rate (or duration) selection alphabet.

  10. 77 FR 41258 - FOIA Fee Schedule Update

    Science.gov (United States)

    2012-07-13

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD 10 CFR Part 1703 FOIA Fee Schedule Update AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Establishment of FOIA Fee Schedule. SUMMARY: The Defense Nuclear Facilities Safety Board is publishing its Freedom of Information Act (FOIA) Fee Schedule Update pursuant to...

  11. 76 FR 43819 - FOIA Fee Schedule Update

    Science.gov (United States)

    2011-07-22

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD 10 CFR Part 1703 FOIA Fee Schedule Update AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Establishment of FOIA Fee Schedule. SUMMARY: The Defense Nuclear Facilities Safety Board is publishing its Freedom of Information Act (FOIA) Fee Schedule Update pursuant to...

  12. 75 FR 7411 - Schedule of Water Charges

    Science.gov (United States)

    2010-02-19

    ... DELAWARE RIVER BASIN COMMISSION 18 CFR Part 410 Schedule of Water Charges AGENCY: Delaware River... Administrative Manual--Part III--Basin Regulations--Water Supply Charges to revise the schedule of water charges... commenter and the subject line ``Schedule of Water Charges.'' FOR FURTHER INFORMATION, CONTACT: Please...

  13. Mechanisms for scheduling games with selfish players

    NARCIS (Netherlands)

    Hoeksma, R.P.

    2015-01-01

    Many challenges in operations research involve optimization. In particular, scheduling treats the optimal planning of tasks. This thesis focuses on machine scheduling models, where a number of tasks, called jobs, need to be scheduled on one or more machines. The outcome is determined by which job is

  14. "The stone which the builders rejected...": Delay of reinforcement and response rate on fixed-interval and related schedules.

    Science.gov (United States)

    Wearden, J H; Lejeune, Helga

    2006-02-28

    The article deals with response rates (mainly running and peak or terminal rates) on simple and on some mixed-FI schedules and explores the idea that these rates are determined by the average delay of reinforcement for responses occurring during the response periods that the schedules generate. The effects of reinforcement delay are assumed to be mediated by a hyperbolic delay of reinforcement gradient. The account predicts that (a) running rates on simple FI schedules should increase with increasing rate of reinforcement, in a manner close to that required by Herrnstein's equation, (b) improving temporal control during acquisition should be associated with increasing running rates, (c) two-valued mixed-FI schedules with equiprobable components should produce complex results, with peak rates sometimes being higher on the longer component schedule, and (d) that effects of reinforcement probability on mixed-FI should affect the response rate at the time of the shorter component only. All these predictions were confirmed by data, although effects in some experiments remain outside the scope of the model. In general, delay of reinforcement as a determinant of response rate on FI and related schedules (rather than temporal control on such schedules) seems a useful starting point for a more thorough analysis of some neglected questions about performance on FI and related schedules.

  15. Multi-objective Mobile Robot Scheduling Problem with Dynamic Time Windows

    DEFF Research Database (Denmark)

    Dang, Vinh Quang; Nielsen, Izabela Ewa; Steger-Jensen, Kenn

    2012-01-01

    This paper deals with the problem of scheduling feeding tasks of a single mobile robot which has capability of supplying parts to feeders on pro-duction lines. The performance criterion is to minimize the total traveling time of the robot and the total tardiness of the feeding tasks being scheduled...

  16. Gain and exposure scheduling to compensate for photorefractive neural-network weight decay

    Science.gov (United States)

    Goldstein, Adam A.; Petrisor, Gregory C.; Jenkins, B. Keith

    1995-03-01

    A gain and exposure schedule that theoretically eliminates the effect of photorefractive weight decay for the general class of outer-product neural-network learning algorithms (e.g., backpropagation, Widrow-Hoff, perceptron) is presented. This schedule compensates for photorefractive diffraction-efficiency decay by iteratively increasing the spatial-light-modulator transfer function gain and decreasing the weight-update exposure time. Simulation results for the scheduling procedure, as applied to backpropagation learning for the exclusive-OR problem, show improved learning performance compared with results for networks trained without scheduling.

  17. Research and Applications of Shop Scheduling Based on Genetic Algorithms

    Directory of Open Access Journals (Sweden)

    Hang ZHAO

    Full Text Available ABSTRACT Shop Scheduling is an important factor affecting the efficiency of production, efficient scheduling method and a research and application for optimization technology play an important role for manufacturing enterprises to improve production efficiency, reduce production costs and many other aspects. Existing studies have shown that improved genetic algorithm has solved the limitations that existed in the genetic algorithm, the objective function is able to meet customers' needs for shop scheduling, and the future research should focus on the combination of genetic algorithm with other optimized algorithms. In this paper, in order to overcome the shortcomings of early convergence of genetic algorithm and resolve local minimization problem in search process,aiming at mixed flow shop scheduling problem, an improved cyclic search genetic algorithm is put forward, and chromosome coding method and corresponding operation are given.The operation has the nature of inheriting the optimal individual ofthe previous generation and is able to avoid the emergence of local minimum, and cyclic and crossover operation and mutation operation can enhance the diversity of the population and then quickly get the optimal individual, and the effectiveness of the algorithm is validated. Experimental results show that the improved algorithm can well avoid the emergency of local minimum and is rapid in convergence.

  18. A General State-Space Formulation for Online Scheduling

    Directory of Open Access Journals (Sweden)

    Dhruv Gupta

    2017-11-01

    Full Text Available We present a generalized state-space model formulation particularly motivated by an online scheduling perspective, which allows modeling (1 task-delays and unit breakdowns; (2 fractional delays and unit downtimes, when using discrete-time grid; (3 variable batch-sizes; (4 robust scheduling through the use of conservative yield estimates and processing times; (5 feedback on task-yield estimates before the task finishes; (6 task termination during its execution; (7 post-production storage of material in unit; and (8 unit capacity degradation and maintenance. Through these proposed generalizations, we enable a natural way to handle routinely encountered disturbances and a rich set of corresponding counter-decisions. Thereby, greatly simplifying and extending the possible application of mathematical programming based online scheduling solutions to diverse application settings. Finally, we demonstrate the effectiveness of this model on a case study from the field of bio-manufacturing.

  19. It Is Not Just about the Schedule: Key Factors in Effective Reference Desk Scheduling and Management

    Science.gov (United States)

    Sciammarella, Susan; Fernandes, Maria Isabel; McKay, Devin

    2008-01-01

    Reference desk scheduling is one of the most challenging tasks in the organizational structure of an academic library. The ability to turn this challenge into a workable and effective function lies with the scheduler and indirectly the cooperation of all librarians scheduled for reference desk service. It is the scheduler's sensitivity to such…

  20. Enhanced OTSG economics optimizing CAPEX + OPEX + Schedule

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, Peter [KTI Engineered to Perform (Canada)

    2011-07-01

    This presentation gives an insight into the economics involved in producing once-through steam (OTSG) generators in Canada and it offers a proposal for improving returns in the industry. The objective of this presentation was to show the importance of developing OTSG manufacturing based on the future of this technology. The growing demand for OTSG by oil companies was presented, suggesting that this is a good time to put effort into developing more efficient designs. After the background of this technology was discussed, several economical aspects of the process were addressed; for instance, reducing capital expenditure (CAPEX) and operation expenditure (OPEX), outsourcing production, and project scheduling and execution. Initiatives proposed included: reducing plot size, producing larger OTSGs, reducing downtime, using alternative fuels, forming a global manufacturing network, and avoiding order blockage. Finally, the idea of designing a portable OTSG was proposed, showing its flexibility in oil extraction projects.

  1. Optimization of a shorter variable-acquisition time for legs to achieve true whole-body PET/CT images.

    Science.gov (United States)

    Umeda, Takuro; Miwa, Kenta; Murata, Taisuke; Miyaji, Noriaki; Wagatsuma, Kei; Motegi, Kazuki; Terauchi, Takashi; Koizumi, Mitsuru

    2017-12-01

    The present study aimed to qualitatively and quantitatively evaluate PET images as a function of acquisition time for various leg sizes, and to optimize a shorter variable-acquisition time protocol for legs to achieve better qualitative and quantitative accuracy of true whole-body PET/CT images. The diameters of legs to be modeled as phantoms were defined based on data derived from 53 patients. This study analyzed PET images of a NEMA phantom and three plastic bottle phantoms (diameter, 5.68, 8.54 and 10.7 cm) that simulated the human body and legs, respectively. The phantoms comprised two spheres (diameters, 10 and 17 mm) containing fluorine-18 fluorodeoxyglucose solution with sphere-to-background ratios of 4 at a background radioactivity level of 2.65 kBq/mL. All PET data were reconstructed with acquisition times ranging from 10 to 180, and 1200 s. We visually evaluated image quality and determined the coefficient of variance (CV) of the background, contrast and the quantitative %error of the hot spheres, and then determined two shorter variable-acquisition protocols for legs. Lesion detectability and quantitative accuracy determined based on maximum standardized uptake values (SUV max ) in PET images of a patient using the proposed protocols were also evaluated. A larger phantom and a shorter acquisition time resulted in increased background noise on images and decreased the contrast in hot spheres. A visual score of ≥ 1.5 was obtained when the acquisition time was ≥ 30 s for three leg phantoms, and ≥ 120 s for the NEMA phantom. The quantitative %errors of the 10- and 17-mm spheres in the leg phantoms were ± 15 and ± 10%, respectively, in PET images with a high CV (scan mean SUV max of three lesions using the current fixed-acquisition and two proposed variable-acquisition time protocols in the clinical study were 3.1, 3.1 and 3.2, respectively, which did not significantly differ. Leg acquisition time per bed position of even 30-90

  2. Meta-heuristic algorithms for parallel identical machines scheduling problem with weighted late work criterion and common due date.

    Science.gov (United States)

    Xu, Zhenzhen; Zou, Yongxing; Kong, Xiangjie

    2015-01-01

    To our knowledge, this paper investigates the first application of meta-heuristic algorithms to tackle the parallel machines scheduling problem with weighted late work criterion and common due date ([Formula: see text]). Late work criterion is one of the performance measures of scheduling problems which considers the length of late parts of particular jobs when evaluating the quality of scheduling. Since this problem is known to be NP-hard, three meta-heuristic algorithms, namely ant colony system, genetic algorithm, and simulated annealing are designed and implemented, respectively. We also propose a novel algorithm named LDF (largest density first) which is improved from LPT (longest processing time first). The computational experiments compared these meta-heuristic algorithms with LDF, LPT and LS (list scheduling), and the experimental results show that SA performs the best in most cases. However, LDF is better than SA in some conditions, moreover, the running time of LDF is much shorter than SA.

  3. Cure Schedule for Stycast 2651/Catalyst 9.

    Energy Technology Data Exchange (ETDEWEB)

    Kropka, Jamie Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); McCoy, John D. [New Mexico Inst. of Mining and Technology, Socorro, NM (United States)

    2017-11-01

    The Emerson & Cuming technical data sheet (TDS) for Stycast 2651/Catalyst 9 lists three alternate cure schedules for the material, each of which would result in a different state of reaction and different material properties. Here, a cure schedule that attains full reaction of the material is defined. The use of this cure schedule will eliminate variance in material properties due to changes in the cure state of the material, and the cure schedule will serve as the method to make material prior to characterizing properties. The following recommendation uses one of the schedules within the TDS and adds a “post cure” to obtain full reaction.

  4. Designing a prototype of the ITER pulse scheduling system

    International Nuclear Information System (INIS)

    Yamamoto, T.; Yonekawa, I.; Ohta, K.; Hosoyama, H.; Hashimoto, Y.; Wallander, A.; Winter, A.; Sugie, T.; Kusama, Y.; Kawano, Y.; Yoshino, R.

    2012-01-01

    Highlights: ► We designed a prototype of the ITER pulse scheduling system. ► Structure of ITER pulse schedules was designed. ► Validation and automatic value assignment functions were adopted. ► A prototype will be implemented in 2011. - Abstract: A prototype of the ITER pulse scheduling system that prepares and manages parameters for ITER plasma operations has been designed. Based on the analyzed requirements on the system, structure of the parameters and necessary functions were determined. Segment and module structures were tuned to the ITER requirements. Three types of validations assure sanity of the parameters. The design limits check and the operation window check verify whether the values of the parameters do not exceed the limits. The consistency check calculates dependency among parameters in accordance with logics described in a scripting language. The ITER pulse scheduling system provides interface with a physics model and simulator. Some abstract physics parameters are converted to engineering parameters with the physics simulation. The results of simulation such as plasma characteristics of specified parameters are also shown to the researchers. The tool to specify the parameters is data-driven. Therefore, it is flexible for changes of number of the parameters. A prototype is being implemented in 2011. Using the prototype, this design will be verified and refined. The evaluation of the prototype will be a basis of the final production of the ITER pulse scheduling system.

  5. Optimal imaging surveillance schedules after liver-directed therapy for hepatocellular carcinoma.

    Science.gov (United States)

    Boas, F Edward; Do, Bao; Louie, John D; Kothary, Nishita; Hwang, Gloria L; Kuo, William T; Hovsepian, David M; Kantrowitz, Mark; Sze, Daniel Y

    2015-01-01

    To optimize surveillance schedules for the detection of recurrent hepatocellular carcinoma (HCC) after liver-directed therapy. New methods have emerged that allow quantitative analysis and optimization of surveillance schedules for diseases with substantial rates of recurrence such as HCC. These methods were applied to 1,766 consecutive chemoembolization, radioembolization, and radiofrequency ablation procedures performed on 910 patients between 2006 and 2011. Computed tomography or magnetic resonance imaging performed just before repeat therapy was set as the time of "recurrence," which included residual and locally recurrent tumor as well as new liver tumors. Time-to-recurrence distribution was estimated by Kaplan-Meier method. Average diagnostic delay (time between recurrence and detection) was calculated for each proposed surveillance schedule using the time-to-recurrence distribution. An optimized surveillance schedule could then be derived to minimize the average diagnostic delay. Recurrence is 6.5 times more likely in the first year after treatment than in the second. Therefore, screening should be much more frequent in the first year. For eight time points in the first 2 years of follow-up, the optimal schedule is 2, 4, 6, 8, 11, 14, 18, and 24 months. This schedule reduces diagnostic delay compared with published schedules and is cost-effective. The calculated optimal surveillance schedules include shorter-interval follow-up when there is a higher probability of recurrence and longer-interval follow-up when there is a lower probability. Cost can be optimized for a specified acceptable diagnostic delay or diagnostic delay can be optimized within a specified acceptable cost. Copyright © 2015 SIR. Published by Elsevier Inc. All rights reserved.

  6. Optimizing Unmanned Aircraft System Scheduling

    Science.gov (United States)

    2008-06-01

    ASC-U uses a deterministic algorithm to optimize over a given finite time horizon to obtain near-optimal UAS mission area assignments. ASC-U...the details of the algorithm . We set an upper bound on the total number of schedules that can be generated, so as not to create unsolvable ILPs. We...COL_MISSION_NAME)) If Trim( CStr (rMissions(iRow, COL_MISSION_REQUIRED))) <> "" Then If CLng(rMissions(iRow, COL_MISSION_REQUIRED)) > CLng

  7. A System for Automatically Generating Scheduling Heuristics

    Science.gov (United States)

    Morris, Robert

    1996-01-01

    The goal of this research is to improve the performance of automated schedulers by designing and implementing an algorithm by automatically generating heuristics by selecting a schedule. The particular application selected by applying this method solves the problem of scheduling telescope observations, and is called the Associate Principal Astronomer. The input to the APA scheduler is a set of observation requests submitted by one or more astronomers. Each observation request specifies an observation program as well as scheduling constraints and preferences associated with the program. The scheduler employs greedy heuristic search to synthesize a schedule that satisfies all hard constraints of the domain and achieves a good score with respect to soft constraints expressed as an objective function established by an astronomer-user.

  8. Routine environmental monitoring schedule, calendar year 1995

    International Nuclear Information System (INIS)

    Schmidt, J.W.; Markes, B.M.; McKinney, S.M.

    1994-12-01

    This document provides Bechtel Hanford, Inc. (BHI) and Westinghouse Hanford Company (WHC) a schedule of monitoring and sampling routines for the Operational Environmental Monitoring (OEM) program during calendar year (CY) 1995. Every attempt will be made to consistently follow this schedule; any deviation from this schedule will be documented by an internal memorandum (DSI) explaining the reason for the deviation. The DSI will be issued by the scheduled performing organization and directed to Near-Field Monitoring. The survey frequencies for particular sites are determined by the technical judgment of Near-Field Monitoring and may depend on the site history, radiological status, use and general conditions. Additional surveys may be requested at irregular frequencies if conditions warrant. All radioactive wastes sites are scheduled to be surveyed at least annually. Any newly discovered wastes sites not documented by this schedule will be included in the revised schedule for CY 1995

  9. TIA model is attainable in Wistar rats by intraluminal occlusion of the MCA for 10min or shorter.

    Science.gov (United States)

    Durukan Tolvanen, A; Tatlisumak, E; Pedrono, E; Abo-Ramadan, U; Tatlisumak, T

    2017-05-15

    Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the event animals are free from any sensorimotor deficit and from any detectable lesion by magnetic resonance imaging (MRI). Animals experienced varying durations of ischemia (5, 10, 12.5, 15, 25, and 30min, n=6-8pergroup) by intraluminal middle cerebral artery occlusion (MCAO). Ischemia severity and reperfusion rates were controlled by cerebral blood flow measurements. Sensorimotor neurological evaluations and MRI at 24h differentiated between TIA and ischemic stroke. Hematoxylin and eosin staining and apoptotic cell counts revealed pathological correlates of the event. We found that already 12.5min of ischemia was long enough to induce ischemic stroke in Wistar rats. Ten min or shorter durations induced neither gross neurological deficits nor infarcts visible on MRI, but histologically caused selective neuronal necrosis. A separate group of animals with 10min of ischemia followed up to 1week after reperfusion remained free of infarction and any MRI signal change. Thus, 10min or shorter focal cerebral ischemia induced by intraluminal MCAO in Wistar rats provides a clinically relevant TIA the rat. This model is useful for studying molecular correlates of TIA. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Use of a novel shorter minimum caliber needle for creating endoscopic tattoos for preoperative localization: a comparative ex vivo study.

    Science.gov (United States)

    Imai, Kenichiro; Hotta, Kinichi; Ito, Sayo; Yamaguchi, Yuichiro; Kawakami, Takeshi; Wada, Takuya; Igarashi, Kimihiro; Kishida, Yoshihiro; Kinugasa, Yusuke; Kawata, Noboru; Tanaka, Masaki; Kakushima, Naomi; Takizawa, Kohei; Ishiwatari, Hirotoshi; Matsubayashi, Hiroyuki; Ono, Hiroyuki

    2017-06-01

    In colorectal cancer surgery, inadvertent deep injections during endoscopic tattooing can cause India ink leakage into the peritoneum, leading to complications or to poor visualization of the surgical plane. This ex vivo animal study compared the use of novel shorter, minimum caliber needles versus conventional injection needles for endoscopic tattooing. Four endoscopists used the novel needles and conventional needles to make ten endoscopic tattoos (five tattoos/needle type/endoscopist) in harvested porcine rectum using a saline test-injection method. India ink leakage and the success of the tattoo (i. e. visible, tattoos but for none of the novel needle tattoos ( P  = 0.02). Tattoos created using the novel needles were more successful than those made with the conventional needles: 18/20 (90 %) vs. 11/20 (55 %); P  = 0.01. The use of novel shorter minimum caliber needles may be safe and effective for endoscopic tattooing for preoperative localization prior to colorectal cancer surgery.

  11. Schedule optimization study implementation plan

    International Nuclear Information System (INIS)

    1993-11-01

    This Implementation Plan is intended to provide a basis for improvements in the conduct of the Environmental Restoration (ER) Program at Hanford. The Plan is based on the findings of the Schedule Optimization Study (SOS) team which was convened for two weeks in September 1992 at the request of the U.S. Department of Energy (DOE) Richland Operations Office (RL). The need for the study arose out of a schedule dispute regarding the submission of the 1100-EM-1 Operable Unit (OU) Remedial Investigation/Feasibility Study (RI/FS) Work Plan. The SOS team was comprised of independent professionals from other federal agencies and the private sector experienced in environmental restoration within the federal system. The objective of the team was to examine reasons for the lengthy RI/FS process and recommend ways to expedite it. The SOS team issued their Final Report in December 1992. The report found the most serious impediments to cleanup relate to a series of management and policy issues which are within the control of the three parties managing and monitoring Hanford -- the DOE, U.S. Environmental Protection Agency (EPA), and the State of Washington Department of Ecology (Ecology). The SOS Report identified the following eight cross-cutting issues as the root of major impediments to the Hanford Site cleanup. Each of these eight issues is quoted from the SOS Report followed by a brief, general description of the proposed approach being developed

  12. Vectorization of a penalty function algorithm for well scheduling

    Science.gov (United States)

    Absar, I.

    1984-01-01

    In petroleum engineering, the oil production profiles of a reservoir can be simulated by using a finite gridded model. This profile is affected by the number and choice of wells which in turn is a result of various production limits and constraints including, for example, the economic minimum well spacing, the number of drilling rigs available and the time required to drill and complete a well. After a well is available it may be shut in because of excessive water or gas productions. In order to optimize the field performance a penalty function algorithm was developed for scheduling wells. For an example with some 343 wells and 15 different constraints, the scheduling routine vectorized for the CYBER 205 averaged 560 times faster performance than the scalar version.

  13. Planning and scheduling for petroleum refineries using mathematical programming

    Directory of Open Access Journals (Sweden)

    Joly M.

    2002-01-01

    Full Text Available The objective of this paper is the development and solution of nonlinear and mixed-integer (MIP optimization models for real-world planning and scheduling problems in petroleum refineries. Firstly, we present a nonlinear planning model that represents a general refinery topology and allows implementation of nonlinear process models as well as blending relations. The optimization model is able to define new operating points, thus increasing the production of the more valuable products and simultaneously satisfying all specification constraints. The second part addresses scheduling problems in oil refineries, which are formulated as MIP optimization models and rely on both continuous and discrete time representations. Three practical applications closely related to the current refinery scenario are presented. The first one addresses the problem of crude oil inventory management of a refinery that receives several types of crude oil delivered exclusively by a single oil pipeline. Subsequently, two optimization models intended to define the optimal production policy, inventory control and distribution are proposed and solved for the fuel oil and asphalt plant. Finally, the planning model of Moro et al. (1998 is extended in order to sequence decisions at the scheduling level in the liquefied petroleum gas (LPG area for maximization of the production of petrochemical-grade propane and product delivery.

  14. 9 CFR 381.303 - Critical factors and the application of the process schedule.

    Science.gov (United States)

    2010-01-01

    ... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Critical factors and the application of the process schedule. 381.303 Section 381.303 Animals and Animal Products FOOD SAFETY AND...

  15. At least 10% shorter C–H bonds in cryogenic protein crystal structures than in current AMBER forcefields

    Energy Technology Data Exchange (ETDEWEB)

    Pang, Yuan-Ping, E-mail: pang@mayo.edu

    2015-03-06

    High resolution protein crystal structures resolved with X-ray diffraction data at cryogenic temperature are commonly used as experimental data to refine forcefields and evaluate protein folding simulations. However, it has been unclear hitherto whether the C–H bond lengths in cryogenic protein structures are significantly different from those defined in forcefields to affect protein folding simulations. This article reports the finding that the C–H bonds in high resolution cryogenic protein structures are 10–14% shorter than those defined in current AMBER forcefields, according to 3709 C–H bonds in the cryogenic protein structures with resolutions of 0.62–0.79 Å. Also, 20 all-atom, isothermal–isobaric, 0.5-μs molecular dynamics simulations showed that chignolin folded from a fully-extended backbone formation to the native β-hairpin conformation in the simulations using AMBER forcefield FF12SB at 300 K with an aggregated native state population including standard error of 10 ± 4%. However, the aggregated native state population with standard error reduced to 3 ± 2% in the same simulations except that C–H bonds were shortened by 10–14%. Furthermore, the aggregated native state populations with standard errors increased to 35 ± 3% and 26 ± 3% when using FF12MC, which is based on AMBER forcefield FF99, with and without the shortened C–H bonds, respectively. These results show that the 10–14% bond length differences can significantly affect protein folding simulations and suggest that re-parameterization of C–H bonds according to the cryogenic structures could improve the ability of a forcefield to fold proteins in molecular dynamics simulations. - Highlights: • Cryogenic crystal structures are commonly used in computational studies of proteins. • C–H bonds in the cryogenic structures are shorter than those defined in forcefields. • A survey of 3709 C–H bonds shows that the cryogenic bonds are 10–14% shorter. • The

  16. Shorter telomeres in peripheral blood mononuclear cells from older persons with sarcopenia: results from an exploratory study

    Directory of Open Access Journals (Sweden)

    Emanuele eMarzetti

    2014-08-01

    Full Text Available Background. Telomere shortening in peripheral blood mononuclear cells (PBMCs has been associated with biological age and several chronic degenerative diseases. However, the relationship between telomere length and sarcopenia, a hallmark of the aging process, is unknown. The aim of the present study was therefore to determine whether PBMC telomeres obtained from sarcopenic older persons were shorter relative to non-sarcopenic peers. We further explored if PBMC telomere length was associated with frailty, a major clinical correlate of sarcopenia.Methods. Analyses were conducted in 142 persons aged >/= 65 years referred to a geriatric outpatient clinic (University Hospital. The presence of sarcopenia was established according to the European Working Group on Sarcopenia in Older People criteria, with bioelectrical impedance analysis used for muscle mass estimation. The frailty status was determined by both the Fried’s criteria (physical frailty, PF and a modified Rockwood’s frailty index (FI. Telomere length was measured in PBMCs by quantitative real-time polymerase chain reaction according to the Telomere/Single copy gene ratio (T/S method.Results. Among 142 outpatients (mean age 75.0 ± 6.5 years, 59.2% women, sarcopenia was diagnosed in 23 individuals (19.3%. The PF phenotype was detected in 74 participants (52.1%. The average FI score was 0.46 ± 0.17. PBMC telomeres were shorter in sarcopenic subjects (T/S = 0.21; 95% CI: 0.18 – 0.24 relative to non-sarcopenic individuals (T/S = 0.26; 95%: CI: 0.24 – 0.28; p = 0.01, independent of age, gender, smoking habit, or comorbidity. No significant associations were determined between telomere length and either PF or FI.Conclusion. PBMC telomere length, expressed as T/S values, is shorter in older outpatients with sarcopenia. The cross-sectional assessment of PBMC telomere length is not sufficient at capturing the complex, multidimensional syndrome of frailty.

  17. 76 FR 20518 - Self-Certification and Employee Training of Mail-Order Distributors of Scheduled Listed Chemical...

    Science.gov (United States)

    2011-04-13

    ... regulated sellers--i.e., retail stores and mobile retail vendors--of scheduled listed chemical products. To... scheduled listed chemical products at retail. Sales at retail are those sales intended for personal use... available for public inspection online at http://www.regulations.gov and in the Drug Enforcement...

  18. Planning construction of integrative schedule management for nuclear power project

    International Nuclear Information System (INIS)

    Zeng Zhenglin; Wang Wenying; Peng Fei

    2012-01-01

    This paper introduces the planning construction of integrative schedule management for Nuclear Power Project. It details schedule management system and the requirement of schedulers and the mode of three schedule management flats. And analysis it combing with the implementation of construction water and all special schedules before FCD to further propose the improving and researching direction for the integrative schedule management. (authors)

  19. A Kinetic Model Explains Why Shorter and Less Affine Enzyme-recruiting Oligonucleotides Can Be More Potent

    Directory of Open Access Journals (Sweden)

    Lykke Pedersen

    2014-01-01

    Full Text Available Antisense oligonucleotides complementary to RNA targets promise generality and ease of drug design. The first systemically administered antisense drug was recently approved for treatment and others are in clinical development. Chemical modifications that increase the hybridization affinity of oligonucleotides are reasoned to confer higher potency, i.e., modified oligonucleotides can be dosed at lower concentrations to achieve the same effect. Surprisingly, shorter and less affine oligonucleotides sometimes display increased potency. To explain this apparent contradiction, increased uptake or decreased propensity to form structures have been suggested as possible mechanisms. Here, we provide an alternative explanation that invokes only the kinetics behind oligonucleotide-mediated cleavage of RNA targets. A model based on the law of mass action predicts, and experiments support, the existence of an optimal binding affinity. Exaggerated affinity, and not length per se, is detrimental to potency. This finding clarifies how to optimally apply high-affinity modifications in the discovery of potent antisense oligonucleotide drugs.

  20. The CHI 2013 interactive schedule

    DEFF Research Database (Denmark)

    Satyanarayan, Arvind; Strazzulla, Daniel; Klokmose, Clemens Nylandsted

    2013-01-01

    CHI 2013 offers over 500 separate events including paper presentations, panels, courses, case studies and special interest groups. Given the size of the conference, it is no longer practical to host live summaries of these events. Instead, a 30-second Video Preview summary of each event is availa......CHI 2013 offers over 500 separate events including paper presentations, panels, courses, case studies and special interest groups. Given the size of the conference, it is no longer practical to host live summaries of these events. Instead, a 30-second Video Preview summary of each event...... is available. The CHI'13 Interactive Schedule helps attendees navigate this wealth of video content in order to identify events they would like to attend. It consists of a number of large display screens throughout the conference venue which cycle through a video playlist of events. Attendees can interact...

  1. The ASDEX Upgrade discharge schedule

    International Nuclear Information System (INIS)

    Neu, G.; Engelhardt, K.; Raupp, G.; Treutterer, W.; Zasche, D.; Zehetbauer, T.

    2007-01-01

    ASDEX Upgrade's recently commissioned discharge control system (DCS) marks the transition from a traditional programmed system to a highly flexible 'data driven' one. The allocation of application processes (APs) to controllers, the interconnection of APs through uniquely named signals, and AP control parameter values are all defined as data, and can easily be adapted to the requirements of a particular discharge. The data is laid down in a set of XML documents which APs request via HTTP from a configuration server before a discharge. The use of XML allows for easy parsing, and structural validation through (XSD) schemas. The central input to the configuration process is the discharge schedule (DS), which embodies the dynamic behaviour of a planned discharge as reference trajectories grouped in segments, concatenated through transition conditions. Editing, generation and validation tools, and version control through CVS allow for efficient management of DSs

  2. Planning and Scheduling of Airline Operations

    Directory of Open Access Journals (Sweden)

    İlkay ORHAN

    2010-02-01

    Full Text Available The Turkish Civil Aviation sector has grown at a rate of 53 % between the years 2002-2008 owing to countrywide economical developments and some removed restrictions in the aviation field. Successful international companies in the sector use advanced computer-supported solution methods for their planning and scheduling problems. These methods have been providing significant competitive advantages to those companies. There are four major scheduling and planning problems in the airline sector: flight scheduling, aircraft scheduling, crew scheduling and disruptions management. These aforementioned scheduling and planning problems faced by all airline companies in the airline sector were examined in detail. Studies reveal that companies using the advanced methods might gain significant cost reductions. However, even then, the time required for solving large scale problems may not satisfy the decision quality desired by decision makers. In such cases, using modern decision methods integrated with advanced technologies offer companies an opportunity for significant cost-advantages.

  3. Optimization of Hierarchically Scheduled Heterogeneous Embedded Systems

    DEFF Research Database (Denmark)

    Pop, Traian; Pop, Paul; Eles, Petru

    2005-01-01

    We present an approach to the analysis and optimization of heterogeneous distributed embedded systems. The systems are heterogeneous not only in terms of hardware components, but also in terms of communication protocols and scheduling policies. When several scheduling policies share a resource......, they are organized in a hierarchy. In this paper, we address design problems that are characteristic to such hierarchically scheduled systems: assignment of scheduling policies to tasks, mapping of tasks to hardware components, and the scheduling of the activities. We present algorithms for solving these problems....... Our heuristics are able to find schedulable implementations under limited resources, achieving an efficient utilization of the system. The developed algorithms are evaluated using extensive experiments and a real-life example....

  4. Spindle assembly checkpoint protein expression correlates with cellular proliferation and shorter time to recurrence in ovarian cancer.

    LENUS (Irish Health Repository)

    McGrogan, Barbara

    2014-07-01

    Ovarian carcinoma (OC) is the most lethal of the gynecological malignancies, often presenting at an advanced stage. Treatment is hampered by high levels of drug resistance. The taxanes are microtubule stabilizing agents, used as first-line agents in the treatment of OC that exert their apoptotic effects through the spindle assembly checkpoint. BUB1-related protein kinase (BUBR1) and mitotic arrest deficient 2 (MAD2), essential spindle assembly checkpoint components, play a key role in response to taxanes. BUBR1, MAD2, and Ki-67 were assessed on an OC tissue microarray platform representing 72 OC tumors of varying histologic subtypes. Sixty-one of these patients received paclitaxel and platinum agents combined; 11 received platinum alone. Overall survival was available for all 72 patients, whereas recurrence-free survival (RFS) was available for 66 patients. Increased BUBR1 expression was seen in serous carcinomas, compared with other histologies (P = .03). Increased BUBR1 was significantly associated with tumors of advanced stage (P = .05). Increased MAD2 and BUBR1 expression also correlated with increased cellular proliferation (P < .0002 and P = .02, respectively). Reduced MAD2 nuclear intensity was associated with a shorter RFS (P = .03), in ovarian tumors of differing histologic subtype (n = 66). In this subgroup, for those women who received paclitaxel and platinum agents combined (n = 57), reduced MAD2 intensity also identified women with a shorter RFS (P < .007). For the entire cohort of patients, irrespective of histologic subtype or treatment, MAD2 nuclear intensity retained independent significance in a multivariate model, with tumors showing reduced nuclear MAD2 intensity identifying patients with a poorer RFS (P = .05).

  5. The association between post-traumatic stress disorder and shorter telomere length: A systematic review and meta-analysis.

    Science.gov (United States)

    Li, Xuemei; Wang, Jiang; Zhou, Jianghua; Huang, Pan; Li, Jiping

    2017-08-15

    Post-traumatic stress disorder (PTSD) is a common psychiatric disorder, which may accelerate aging. Many study have investigated the association between telomeres length and PTSD, but results from published studies are contradictory. Therefore, Meta-analysis approaches were conducted to give more precise estimate of relationship between telomere length and PTSD. We systematically reviewed the databases of PUBMED, PsycINFO, Medline(Ovid SP) and EMBASE for all articles on the association between telomere length and PTSD. Data were summarized by using random-effects in the meta-analysis. The heterogeneity among studies were examined by using Cochrane's Q statistic and I-squared. Five eligible studies containing 3851 participants were included in our meta-analysis. Shorten telomere length was significantly associated with PTSD with mean difference of -0.19( 95% CI: -0.27, -0.01; P<0.001) with I-square of 96%. The results from subgroup analysis demonstrated that shorter telomere length was significantly associated with PTSD across all gender groups, with mean difference of -0.15( 95% CI: -0.29, -0.01; P=0.04) for female, mean difference of -0.17( 95% CI: -0.19, -0.15; P<0.001) for male. Meanwhile, shorten telomere length was significantly associated with sexual assault(mean difference =-0.15, 95% CI: -0.29, -0.01), childhood trauma (mean difference =-0.08, 95% CI: -0.19, -0.07), but not combat (mean difference =-0.39, 95% CI: -0.83, 0.05). Compared to the individuals without PTSD, individuals with PTSD have shorter telomere length, which has implications for early intervention and timely treatment to prevent future adverse health outcomes. Copyright © 2017. Published by Elsevier B.V.

  6. On Coding of Scheduling Information in OFDM

    OpenAIRE

    Gunnarsson, Fredrik; Moosavi, Reza; Eriksson, Jonas; Larsson, Erik G.; Wiberg, Niklas; Frenger, Pål

    2009-01-01

    Control signaling strategies for scheduling information in cellular OFDM systems are studied. A single-cell multiuser system model is formulated that provides system capacity estimates accounting for the signaling overhead. Different scheduling granularities are considered, including the one used in the specifications for the 3G Long Term Evolution (LTE). A greedy scheduling method is assumed, where each resource is assigned to the user for which it can support the highest number of bits. The...

  7. Management of Temporal Constraints for Factory Scheduling.

    Science.gov (United States)

    1987-06-01

    consistency of scheduling decisions were implemented in both the ISIS [Fox 84] and SOJA [LePape 85a] scheduling systems. More recent work with the...kinds of time propagation systems: the symbolic and the numeric ones. Symbolic systems combine relationships with a temporal logic a la Allen [Allen 81...maintains consistency by narrowing time windows associated with activities as decisions are made, and SOJA [LePape 85b] guarantees a schedule’s

  8. Cost effective shift schedules enhance utility operations

    International Nuclear Information System (INIS)

    Coleman, R.M.

    1995-01-01

    This article describes how new shift scheduling concepts can save utility operations millions of dollars every year and yet maintain safety and improve employee morale. The key to scheduling is to define and match the work load. This includes discretionary as well as daily, weekly, and yearly core work loads. In most power plants the overall work load (including maintenance, operations, materials handling, etc.) on day shift is greater than on other shifts, hence an unbalanced schedule would be appropriate

  9. Trustable Virtual Machine Scheduling in a Cloud

    OpenAIRE

    Hermenier , Fabien; Henrio , Ludovic

    2017-01-01

    International audience; In an Infrastructure As A Service (IaaS) cloud, the scheduler deploys VMs to servers according to service level objectives (SLOs). Clients and service providers must both trust the infrastructure. In particular they must be sure that the VM scheduler takes decisions that are consistent with its advertised behaviour. The difficulties to master every theoretical and practical aspects of a VM scheduler implementation leads however to faulty behaviours that break SLOs and ...

  10. Flow shop scheduling with heterogeneous workers

    OpenAIRE

    Benavides, Alexander J.; Ritt, Marcus; Miralles Insa, Cristóbal Javier

    2014-01-01

    We propose an extension to the flow shop scheduling problem named Heterogeneous Flow Shop Scheduling Problem (Het-FSSP), where two simultaneous issues have to be resolved: finding the best worker assignment to the workstations, and solving the corresponding scheduling problem. This problem is motivated by Sheltered Work centers for Disabled, whose main objective is the labor integration of persons with disabilities, an important aim not only for these centers but for any company d...

  11. A hybrid job-shop scheduling system

    Science.gov (United States)

    Hellingrath, Bernd; Robbach, Peter; Bayat-Sarmadi, Fahid; Marx, Andreas

    1992-01-01

    The intention of the scheduling system developed at the Fraunhofer-Institute for Material Flow and Logistics is the support of a scheduler working in a job-shop. Due to the existing requirements for a job-shop scheduling system the usage of flexible knowledge representation and processing techniques is necessary. Within this system the attempt was made to combine the advantages of symbolic AI-techniques with those of neural networks.

  12. LEARNING SCHEDULER PARAMETERS FOR ADAPTIVE PREEMPTION

    OpenAIRE

    Prakhar Ojha; Siddhartha R Thota; Vani M; Mohit P Tahilianni

    2015-01-01

    An operating system scheduler is expected to not allow processor stay idle if there is any process ready or waiting for its execution. This problem gains more importance as the numbers of processes always outnumber the processors by large margins. It is in this regard that schedulers are provided with the ability to preempt a running process, by following any scheduling algorithm, and give us an illusion of simultaneous running of several processes. A process which is allowed t...

  13. Spent nuclear fuel project integrated schedule plan

    International Nuclear Information System (INIS)

    Squires, K.G.

    1995-01-01

    The Spent Nuclear Fuel Integrated Schedule Plan establishes the organizational responsibilities, rules for developing, maintain and status of the SNF integrated schedule, and an implementation plan for the integrated schedule. The mission of the SNFP on the Hanford site is to provide safe, economic, environmentally sound management of Hanford SNF in a manner which stages it to final disposition. This particularly involves K Basin fuel

  14. Spent nuclear fuel project integrated schedule plan

    Energy Technology Data Exchange (ETDEWEB)

    Squires, K.G.

    1995-03-06

    The Spent Nuclear Fuel Integrated Schedule Plan establishes the organizational responsibilities, rules for developing, maintain and status of the SNF integrated schedule, and an implementation plan for the integrated schedule. The mission of the SNFP on the Hanford site is to provide safe, economic, environmentally sound management of Hanford SNF in a manner which stages it to final disposition. This particularly involves K Basin fuel.

  15. Cloud Service Scheduling Algorithm Research and Optimization

    Directory of Open Access Journals (Sweden)

    Hongyan Cui

    2017-01-01

    Full Text Available We propose a cloud service scheduling model that is referred to as the Task Scheduling System (TSS. In the user module, the process time of each task is in accordance with a general distribution. In the task scheduling module, we take a weighted sum of makespan and flowtime as the objective function and use an Ant Colony Optimization (ACO and a Genetic Algorithm (GA to solve the problem of cloud task scheduling. Simulation results show that the convergence speed and output performance of our Genetic Algorithm-Chaos Ant Colony Optimization (GA-CACO are optimal.

  16. A customizable, scalable scheduling and reporting system.

    Science.gov (United States)

    Wood, Jody L; Whitman, Beverly J; Mackley, Lisa A; Armstrong, Robert; Shotto, Robert T

    2014-06-01

    Scheduling is essential for running a facility smoothly and for summarizing activities in use reports. The Penn State Hershey Clinical Simulation Center has developed a scheduling interface that uses off-the-shelf components, with customizations that adapt to each institution's data collection and reporting needs. The system is designed using programs within the Microsoft Office 2010 suite. Outlook provides the scheduling component, while the reporting is performed using Access or Excel. An account with a calendar is created for the main schedule, with separate resource accounts created for each room within the center. The Outlook appointment form's 2 default tabs are used, in addition to a customized third tab. The data are then copied from the calendar into either a database table or a spreadsheet, where the reports are generated.Incorporating this system into an institution-wide structure allows integration of personnel lists and potentially enables all users to check the schedule from their desktop. Outlook also has a Web-based application for viewing the basic schedule from outside the institution, although customized data cannot be accessed. The scheduling and reporting functions have been used for a year at the Penn State Hershey Clinical Simulation Center. The schedule has increased workflow efficiency, improved the quality of recorded information, and provided more accurate reporting. The Penn State Hershey Clinical Simulation Center's scheduling and reporting system can be adapted easily to most simulation centers and can expand and change to meet future growth with little or no expense to the center.

  17. 15 CFR 700.14 - Preferential scheduling.

    Science.gov (United States)

    2010-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.14 Preferential scheduling. (a) A...

  18. BIM-BASED SCHEDULING OF CONSTRUCTION

    DEFF Research Database (Denmark)

    Andersson, Niclas; Büchmann-Slorup, Rolf

    2010-01-01

    The potential of BIM is generally recognized in the construction industry, but the practical application of BIM for management purposes is, however, still limited among contractors. The objective of this study is to review the current scheduling process of construction in light of BIM...... and communicate. Scheduling on the detailed level, on the other hand, follows a stipulated approach to scheduling, i.e. the Last Planner System (LPS), which is characterized by involvement of all actors in the construction phase. Thus, the major challenge when implementing BIM-based scheduling is to improve...

  19. PRACTICAL IMPLICATIONS OF LOCATION-BASED SCHEDULING

    DEFF Research Database (Denmark)

    Andersson, Niclas; Christensen, Knud

    2007-01-01

    The traditional method for planning, scheduling and controlling activities and resources in construction projects is the CPM-scheduling, which has been the predominant scheduling method since its introduction in the late 1950s. Over the years, CPM has proven to be a very powerful technique...... that will be used in this study. LBS is a scheduling method that rests upon the theories of line-of-balance and which uses the graphic representation of a flowline chart. As such, LBS is adapted for planning and management of workflows and, thus, may provide a solution to the identified shortcomings of CPM. Even...

  20. Multi-objective group scheduling optimization integrated with preventive maintenance

    Science.gov (United States)

    Liao, Wenzhu; Zhang, Xiufang; Jiang, Min

    2017-11-01

    This article proposes a single-machine-based integration model to meet the requirements of production scheduling and preventive maintenance in group production. To describe the production for identical/similar and different jobs, this integrated model considers the learning and forgetting effects. Based on machine degradation, the deterioration effect is also considered. Moreover, perfect maintenance and minimal repair are adopted in this integrated model. The multi-objective of minimizing total completion time and maintenance cost is taken to meet the dual requirements of delivery date and cost. Finally, a genetic algorithm is developed to solve this optimization model, and the computation results demonstrate that this integrated model is effective and reliable.

  1. Instructions, multiple schedules, and extinction: Distinguishing rule-governed from schedule-controlled behavior.

    Science.gov (United States)

    Hayes, S C; Brownstein, A J; Haas, J R; Greenway, D E

    1986-09-01

    Schedule sensitivity has usually been examined either through a multiple schedule or through changes in schedules after steady-state responding has been established. This study compared the effects of these two procedures when various instructions were given. Fifty-five college students responded in two 32-min sessions under a multiple fixed-ratio 18/differential-reinforcement-of-low-rate 6-s schedule, followed by one session of extinction. Some subjects received no instructions regarding the appropriate rates of responding, whereas others received instructions to respond slowly, rapidly, or both. Relative to the schedule in operation, the instructions were minimal, partially inaccurate, or accurate. When there was little schedule sensitivity in the multiple schedule, there was little in extinction. When apparently schedule-sensitive responding occurred in the multiple schedule, however, sensitivity in extinction occurred only if differential responding in the multiple schedule could not be due to rules supplied by the experimenter. This evidence shows that rule-governed behavior that occurs in the form of schedule-sensitive behavior may not in fact become schedule-sensitive even though it makes contact with the scheduled reinforcers.

  2. Using Optimization Models for Scheduling in Enterprise Resource Planning Systems

    Directory of Open Access Journals (Sweden)

    Frank Herrmann

    2016-03-01

    Full Text Available Companies often use specially-designed production systems and change them from time to time. They produce small batches in order to satisfy specific demands with the least tardiness. This imposes high demands on high-performance scheduling algorithms which can be rapidly adapted to changes in the production system. As a solution, this paper proposes a generic approach: solutions were obtained using a widely-used commercially-available tool for solving linear optimization models, which is available in an Enterprise Resource Planning System (in the SAP system for example or can be connected to it. In a real-world application of a flow shop with special restrictions this approach is successfully used on a standard personal computer. Thus, the main implication is that optimal scheduling with a commercially-available tool, incorporated in an Enterprise Resource Planning System, may be the best approach.

  3. Washington's marine oil spill compensation schedule - simplified resource damage assessment

    International Nuclear Information System (INIS)

    Geselbracht, L.; Logan, R.

    1993-01-01

    The Washington State Preassessment Screening and Oil Spill Compensation Schedule Rule (Chapter 173-183 Washington Administrative Code), which simplifies natural resource damage assessment for many oil spill cases, became effective in May 1992. The approach described in the rule incorporates a number of preconstructed rankings that rate environmental sensitivity and the propensity of spilled oil to cause environmental harm. The rule also provides guidance regarding how damages calculated under the schedule should be reduced to take into account actions taken by the responsible party that reduce environmental injury. To apply the compensation schedule to marine estuarine spills, the resource trustees need only collect a limited amount of information such as type of product spilled, number of gallons spilled, compensation schedule subregions the spill entered, season of greatest spill impact, percent coverage of habitats affected by the spill, and actions taken by the responsible party. The result of adding a simplified tool to the existing assortment of damage assessment approaches is that resource trustees will now be able to assess damages for most oil spill cases and shift more effort than was possible in the past to resource restoration

  4. Solving Flexible Job-Shop Scheduling Problem Using Gravitational Search Algorithm and Colored Petri Net

    Directory of Open Access Journals (Sweden)

    Behnam Barzegar

    2012-01-01

    Full Text Available Scheduled production system leads to avoiding stock accumulations, losses reduction, decreasing or even eliminating idol machines, and effort to better benefitting from machines for on time responding customer orders and supplying requested materials in suitable time. In flexible job-shop scheduling production systems, we could reduce time and costs by transferring and delivering operations on existing machines, that is, among NP-hard problems. The scheduling objective minimizes the maximal completion time of all the operations, which is denoted by Makespan. Different methods and algorithms have been presented for solving this problem. Having a reasonable scheduled production system has significant influence on improving effectiveness and attaining to organization goals. In this paper, new algorithm were proposed for flexible job-shop scheduling problem systems (FJSSP-GSPN that is based on gravitational search algorithm (GSA. In the proposed method, the flexible job-shop scheduling problem systems was modeled by color Petri net and CPN tool and then a scheduled job was programmed by GSA algorithm. The experimental results showed that the proposed method has reasonable performance in comparison with other algorithms.

  5. Parallel Machine Scheduling with Batch Delivery to Two Customers

    Directory of Open Access Journals (Sweden)

    Xueling Zhong

    2015-01-01

    Full Text Available In some make-to-order supply chains, the manufacturer needs to process and deliver products for customers at different locations. To coordinate production and distribution operations at the detailed scheduling level, we study a parallel machine scheduling model with batch delivery to two customers by vehicle routing method. In this model, the supply chain consists of a processing facility with m parallel machines and two customers. A set of jobs containing n1 jobs from customer 1 and n2 jobs from customer 2 are first processed in the processing facility and then delivered to the customers directly without intermediate inventory. The problem is to find a joint schedule of production and distribution such that the tradeoff between maximum arrival time of the jobs and total distribution cost is minimized. The distribution cost of a delivery shipment consists of a fixed charge and a variable cost proportional to the total distance of the route taken by the shipment. We provide polynomial time heuristics with worst-case performance analysis for the problem. If m=2 and (n1-b(n2-b<0, we propose a heuristic with worst-case ratio bound of 3/2, where b is the capacity of the delivery shipment. Otherwise, the worst-case ratio bound of the heuristic we propose is 2-2/(m+1.

  6. The Change of the Family Life Affected by the Shorter Working Time : From the Point of View of the Home Management

    OpenAIRE

    平田, 道憲

    1994-01-01

    In Japan, the working time has been decreasing. However, Japanese working people spend more hours per year to work than those in Western countries. The policy of the shorter working time is conducted by the Japanese Government in order that the working people get more free time. This paper examines whether the shorter working time of working members in the family enrich the time use of the other members of the family. Especially, the effect of the shorter working time of husbands to wives...

  7. 29 CFR 825.203 - Scheduling of intermittent or reduced schedule leave.

    Science.gov (United States)

    2010-07-01

    ... leave intermittently or on a reduced leave schedule for planned medical treatment, then the employee... 29 Labor 3 2010-07-01 2010-07-01 false Scheduling of intermittent or reduced schedule leave. 825... OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the...

  8. Designing cyclic appointment schedules for outpatient clinics with scheduled and unscheduled patient arrivals

    NARCIS (Netherlands)

    Kortbeek, Nikky; Zonderland, Maartje E.; Braaksma, Aleida; Vliegen, Ingrid M. H.; Boucherie, Richard J.; Litvak, Nelly; Hans, Erwin W.

    2014-01-01

    We present a methodology to design appointment systems for outpatient clinics and diagnostic facilities that offer both walk-in and scheduled service. The developed blueprint for the appointment schedule prescribes the number of appointments to plan per day and the moment on the day to schedule the

  9. Designing cyclic appointment schedules for outpatient clinics with scheduled and unscheduled patient arrivals

    NARCIS (Netherlands)

    Kortbeek, Nikky; Zonderland, Maartje Elisabeth; Boucherie, Richardus J.; Litvak, Nelli; Hans, Elias W.

    2011-01-01

    We present a methodology to design appointment systems for outpatient clinics and diagnostic facilities that offer both walk-in and scheduled service. The developed blueprint for the appointment schedule prescribes the number of appointments to plan per day and the moment on the day to schedule the

  10. Accelerating exact schedulability analysis for fixed-priority pre-emptive scheduling

    NARCIS (Netherlands)

    Hang, Y.; Jiale, Z.; Keskin, U.; Bril, R.J.

    2010-01-01

    The schedulability analysis for fixed-priority preemptive scheduling (FPPS) plays a significant role in the real-time systems domain. The so-called Hyperplanes Exact Test (HET) [1] is an example of an exact schedulability test for FPPS. In this paper, we aim at improving the efficiency of HET by

  11. A dynamic approach to vehicle scheduling

    NARCIS (Netherlands)

    D. Huisman (Dennis); R. Freling (Richard); A.P.M. Wagelmans (Albert)

    2001-01-01

    textabstractThis paper presents a dynamic approach to the vehicle scheduling problem. We discuss the potential benefit of our approach compared to the traditional one, where the vehicle scheduling problem is solved only once for a whole period and the travel times are assumed to be fixed. In our

  12. State Teacher Salary Schedules. Policy Analysis

    Science.gov (United States)

    Griffith, Michael

    2016-01-01

    In the United States most teacher compensation issues are decided at the school district level. However, a group of states have chosen to play a role in teacher pay decisions by instituting statewide teacher salary schedules. Education Commission of the States has found that 17 states currently make use of teacher salary schedules. This education…

  13. Evolutionary Scheduler for the Deep Space Network

    Science.gov (United States)

    Guillaume, Alexandre; Lee, Seungwon; Wang, Yeou-Fang; Zheng, Hua; Chau, Savio; Tung, Yu-Wen; Terrile, Richard J.; Hovden, Robert

    2010-01-01

    A computer program assists human schedulers in satisfying, to the maximum extent possible, competing demands from multiple spacecraft missions for utilization of the transmitting/receiving Earth stations of NASA s Deep Space Network. The program embodies a concept of optimal scheduling to attain multiple objectives in the presence of multiple constraints.

  14. Decay-usage scheduling in multiprocessors

    NARCIS (Netherlands)

    Epema, D.H.J.

    1998-01-01

    Decay-usage scheduling is a priority-aging time-sharing scheduling policy capable of dealing with a workload of both interactive and batch jobs by decreasing the priority of a job when it acquires CPU time, and by increasing its priority when it does not use the (a) CPU. In this article we deal with

  15. 5 CFR 950.801 - Campaign schedule.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Campaign schedule. 950.801 Section 950... VOLUNTARY ORGANIZATIONS CFC Timetable § 950.801 Campaign schedule. (a) The Combined Federal Campaign will be.../International and International parts of the Charity List to all local campaigns by a date to be determined by...

  16. 46 CFR 525.2 - Terminal schedules.

    Science.gov (United States)

    2010-10-01

    ... domestic law and international conventions and agreements adopted by the United States; such terminal... their own negligence, or that impose upon others the obligation to indemnify or hold-harmless the terminals from liability for their own negligence. (2) Enforcement of terminal schedules. Any schedule that...

  17. 21 CFR 1308.13 - Schedule III.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Schedule III. 1308.13 Section 1308.13 Food and... opposite it. (b) Stimulants. Unless specifically excepted or unless listed in another schedule, any... a stimulant effect on the central nervous sxstem, including its salts, isomers (whether optical...

  18. Management Matters. Changing to Flexible Scheduling

    Science.gov (United States)

    Pappas, Marjorie L.

    2005-01-01

    Elementary school library media specialists state that one of the most frustrating issues they face is the fixed schedules in their library media centers. Beyond the cost effectiveness issue, the fixed schedule severely limits using the resources of the library media center for inquiry learning and collaborative teaching experiences between the…

  19. Agent-based scheduling for aircraft deicing

    NARCIS (Netherlands)

    Mao, X.; Ter Mors, A.W.; Roos, N.; Witteveen, C.

    2006-01-01

    The planning and scheduling of the deicing and anti-icing activities is an important and challenging part of airport departure planning. Deicing planning has to be done in a highly dynamic environment involving several autonomous and self-interested parties. Traditional centralized scheduling

  20. Robust scheduling in an uncertain environment

    NARCIS (Netherlands)

    Wilson, M.

    2016-01-01

    This thesis presents research on scheduling in an uncertain environment, which forms a part of the rolling stock life cycle logistics applied research and development program funded by Dutch railway industry companies. The focus therefore lies on scheduling of maintenance operations on rolling stock

  1. A novel particle swarm optimization algorithm for permutation flow-shop scheduling to minimize makespan

    International Nuclear Information System (INIS)

    Lian Zhigang; Gu Xingsheng; Jiao Bin

    2008-01-01

    It is well known that the flow-shop scheduling problem (FSSP) is a branch of production scheduling and is NP-hard. Now, many different approaches have been applied for permutation flow-shop scheduling to minimize makespan, but current algorithms even for moderate size problems cannot be solved to guarantee optimality. Some literatures searching PSO for continuous optimization problems are reported, but papers searching PSO for discrete scheduling problems are few. In this paper, according to the discrete characteristic of FSSP, a novel particle swarm optimization (NPSO) algorithm is presented and successfully applied to permutation flow-shop scheduling to minimize makespan. Computation experiments of seven representative instances (Taillard) based on practical data were made, and comparing the NPSO with standard GA, we obtain that the NPSO is clearly more efficacious than standard GA for FSSP to minimize makespan

  2. The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer

    Directory of Open Access Journals (Sweden)

    Lane Denis

    2010-01-01

    Full Text Available Abstract Background The production of ascites is a common complication of ovarian cancer. Ascites constitute a unique tumor microenvironment that may affect disease progression. In this context, we recently showed that ovarian cancer ascites may protect tumor cells from TRAIL-induced apoptosis. In this study, we sought to determine whether the prosurvival effect of ascites affects disease-free intervals. Methods Peritoneal fluids were obtained from 54 women undergoing intra-abdominal surgery for suspected ovarian cancer (44 cancers and 10 benign diseases. The ability of peritoneal fluids to protect from TRAIL was assessed in the ovarian cancer cell line CaOV3, and IC50 were determined. The anti-apoptotic activity of 6 ascites against cisplatin, paclitaxel, doxorubicin, etoposide and vinorelbine was also assessed in CaOV3 cells, and the prosurvival activity of two ascites was assessed in 9 primary ovarian cancer cultures. Results Among the 54 peritoneal fluids tested, inhibition of TRAIL cytotoxicity was variable. Fluids originating from ovarian cancer were generally more protective than fluids from non-malignant diseases. Most of the 44 ovarian cancer ascites increased TRAIL IC50 and this inhibitory effect did not correlate strongly with the protein concentration in these ascites or the levels of serum CA125, a tumor antigen which is used in the clinic as a marker of tumor burden. The effect of ascites on cisplatin- and paclitaxel-induced cell death was assessed with 4 ascites having inhibitory effect on TRAIL-induced cell death and 2 that do not. The four ascites with prosurvival activity against TRAIL had some inhibitory on cisplatin and/or paclitaxel. Two ovarian cancer ascites, OVC346 and OVC509, also inhibited TRAIL cytotoxicity in 9 primary cultures of ovarian tumor and induced Akt activation in three of these primary cultures. Among a cohort of 35 patients with ascites, a threshold of TRAIL IC50 with ascites/IC50 without ascites > 2 was

  3. Progesterone-releasing devices for cattle estrus induction and synchronization: Device optimization to anticipate shorter treatment durations and new device developments.

    Science.gov (United States)

    de Graaff, W; Grimard, B

    2018-05-01

    Synchronization programs using progesterone-releasing intravaginal devices that allow for fixed time artificial insemination are still finding increasing application in bovine reproduction. This practice is useful for rationalizing livestock management because an increased number of cows can be inseminated in one session without the need for estrus detection. Although much of the innovation related to the design and development of intravaginal devices for use in cattle took place in the previous century, progress in understanding the physiology of the bovine estrous cycle resulted in shorter treatment durations, a trend which is still continuing. In this competitive market, with little functional differentiation between the existing devices, the shorter treatment duration prompted for optimization of the progesterone content in the device, as the cost of the drug significantly contributes to the price per unit. For CIDR ® a reduction of the progesterone content of about 30 per cent was realized. Price reduction remained an important target for further device development. Next to reduction of progesterone content, cheaper and easier to process materials like polyethylene vinyl acetate (EVA) copolymers have been explored to replace the commonly used silicone elastomers. The reengineering effort of CIDR ® demonstrated that knowledge of release kinetics and insight into gradual depletion patterns in the device is critical for optimization of drug content without compromising performance (blood levels). More recent publications related to the use of alternative polymers like EVA and polyisoprene (IP) indicated encouraging results regarding further reduction of progesterone content. The use of EVA seems most promising, because it is in principle a low-cost polymer available in many grades and this thermoplastic polymer can be processed easily by means of commonly used techniques like injection molding and extrusion. The use of thermoplastic polymers, however, requires

  4. TECHNICAL COORDINATION, SCHEDULE AND INTEGRATION

    CERN Multimedia

    A. Ball

    Introduction and Schedule After nearly seven months of concentrated effort, the installation of services on YB0 moved off the CMS critical path in late November. In line with v36 planning provisions, the additional time needed to finish this challeng¬ing task was accommodated by reducing sequential dependencies between assembly tasks, putting more tasks (especially heavy logistic movements) in parallel with activities on, or within, the central wheel. Thus the lowering of wheels YB-1 and YB -2 and of disk YE-3 is already complete, the latter made possible, in the shadow of YB0 work, by inverting the order of the 3 endcap disks in the surface building. Weather conditions permitting, the Tracker will be transported to point 5 during CMS week for insertion in EB before CERN closes. The lowering of the last two disks will take place mid- and end-of January, respectively. Thus central beampipe installation can be confidently planned to start in February as foreseen, allowing closure of CMS in time for CRA...

  5. TECHNICAL COORDINATION, SCHEDULE AND INTEGRATION

    CERN Multimedia

    A. Ball

    Introduction Despite the holiday season affecting available manpower, many key internal milestones have been passed over the summer, thanks to the dedication and commitment of the team at point 5. In particular, the installation on, and within, YB0 has progressed steadily through several potentially difficult phases. The v36 planning contingency of lowering YB-1 and YB-1 wheels on schedule in October, before Tracker installation, will be executed in order to give more time to complete YB0 services work, whilst still being consistent with completion of heavy lowering by the end of 2007. Safety In the underground areas the peak level of activity and parallel work has been reached and this will continue for the coming months. Utmost vigilance is required of everybody working underground and this must be maintained. However, it is encouraging to note that the compliance with safety rules is, in general, good. More and more work will be carried out from scaffolding and mobile access platforms. (cherry-picke...

  6. Scheduling mammograms for asymptomatic women

    International Nuclear Information System (INIS)

    Gohagan, J.K.; Darby, W.P.; Spitznagel, E.L.; Tome, A.E.

    1988-01-01

    A decision theoretic model was used to investigate the relative importance of risk level, radiation hazard, mammographic accuracy, and cost in mammographic screening decision. The model uses woman-specific medical and family history facts and clinic-specific information regarding mammographic accuracy and practice to profile both woman and clinic, and to formulate periodic screening recommendations. Model parameters were varied extensively to investigate the sensitivity of screening schedules to input values. Multivariate risk was estimated within the program using published data from the Breast Cancer Detection Demonstration Project 5-year follow-up study. Radiation hazard estimates were developed from published radiation physics and radioepidemiologic risk data. Benchmark values for mammographic sensitivity and specificity under screening conditions were calculated from Breast Cancer Detection Demonstration Project data. Procedural costs used in the analysis were varied around values reflecting conditions at the Washington University Medical Center. Mortality advantages of early versus late breast cancer detection were accounted for using Health Insurance Plan of New York case survival rates. Results are compared with published screening policies to provide insight into implicit assumptions behind those policies. This analysis emphasizes the importance of accounting for variations in clinical accuracy under screening circumstances, in costs, in radiation exposure, and in woman-specific risk when recommending mammographic screening

  7. TECHNICAL COORDINATION, SCHEDULE AND INTEGRATION

    CERN Multimedia

    A. Ball

    Introduction Since the lowering of YB0 in February, less spectacular but nonetheless crucial progress has been made along the critical path to CMS completion. The YB0 has been aligned with the beamline to a fraction of a mm, and the HCAL has been fully installed. Cabling scaffolding for YB0 services has been built and one half (-z end) of the ECAL barrel has been installed. The YB0 services installation has begun, with two of the major technical challenges delaying bulk installation, namely PP1 detailed design, manufacture and installation plus Tracker cooling pipe insulation, now apparently solved. Significant difficulties in detailed design, integration and procurement of cable ducts remain. Despite this, the design of the +end is close to complete, and Tracker power cable installation on two sectors of the +end is well advanced. A new master schedule, v36.0, is being prepared to account for the updated actual situation at point 5 and for the revised LHC machine planning. Safety The enormous amount of...

  8. Production management (2000)

    International Nuclear Information System (INIS)

    Jung, Chung Yeong

    2000-08-01

    This book includes basic concept of production management, production system, strategy and mission of production, decision of production management, operation of decision making, life cycle of items and development, value of productions, design for reliability of productions, equipment layout and manufacturing process, quantitative forecast, schedule plan, inventory system, concept, input and output of MRP, Montekalo simulation, quality management, and automation system.

  9. Effects of a shortened depreciation schedule on the investment costs for combined heat and power; TOPICAL

    International Nuclear Information System (INIS)

    Kranz, Nicole; Worrell, Ernst

    2001-01-01

    We investigate and compare several generic depreciation methods to assess the effectiveness of possible policy measures with respect to the depreciation schedules for investments in combined heat and power plants in the United States. We assess the different depreciation methods for CHP projects of various sizes (ranging from 1 MW to 100 MW). We evaluate the impact of different depreciation schedules on the tax shield, and the resulting tax savings to potential investors. We show that a shorter depreciation cycle could have a substantial impact on the cost of producing power, making cogeneration more attractive. The savings amount to approximately 6-7 percent of capital and fixed operation and maintenance costs, when changing from the current system to a 7 year depreciation scheme with switchover from declining balance to straight line depreciation. Suggestions for further research to improve the analysis are given

  10. Scheduling nursing personnel on a microcomputer.

    Science.gov (United States)

    Liao, C J; Kao, C Y

    1997-01-01

    Suggests that with the shortage of nursing personnel, hospital administrators have to pay more attention to the needs of nurses to retain and recruit them. Also asserts that improving nurses' schedules is one of the most economic ways for the hospital administration to create a better working environment for nurses. Develops an algorithm for scheduling nursing personnel. Contrary to the current hospital approach, which schedules nurses on a person-by-person basis, the proposed algorithm constructs schedules on a day-by-day basis. The algorithm has inherent flexibility in handling a variety of possible constraints and goals, similar to other non-cyclical approaches. But, unlike most other non-cyclical approaches, it can also generate a quality schedule in a short time on a microcomputer. The algorithm was coded in C language and run on a microcomputer. The developed software is currently implemented at a leading hospital in Taiwan. The response to the initial implementation is quite promising.

  11. NASA Instrument Cost/Schedule Model

    Science.gov (United States)

    Habib-Agahi, Hamid; Mrozinski, Joe; Fox, George

    2011-01-01

    NASA's Office of Independent Program and Cost Evaluation (IPCE) has established a number of initiatives to improve its cost and schedule estimating capabilities. 12One of these initiatives has resulted in the JPL developed NASA Instrument Cost Model. NICM is a cost and schedule estimator that contains: A system level cost estimation tool; a subsystem level cost estimation tool; a database of cost and technical parameters of over 140 previously flown remote sensing and in-situ instruments; a schedule estimator; a set of rules to estimate cost and schedule by life cycle phases (B/C/D); and a novel tool for developing joint probability distributions for cost and schedule risk (Joint Confidence Level (JCL)). This paper describes the development and use of NICM, including the data normalization processes, data mining methods (cluster analysis, principal components analysis, regression analysis and bootstrap cross validation), the estimating equations themselves and a demonstration of the NICM tool suite.

  12. 9 CFR 318.303 - Critical factors and the application of the process schedule.

    Science.gov (United States)

    2010-01-01

    ... of the process schedule. 318.303 Section 318.303 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY...; REINSPECTION AND PREPARATION OF PRODUCTS Canning and Canned Products § 318.303 Critical factors and the...

  13. Elevated CD147 expression is associated with shorter overall survival in non-small cell lung cancer.

    Science.gov (United States)

    Zhang, Xiaojun; Tian, Tian; Zhang, Xiaofeng; Liu, Changting; Fang, Xiangqun

    2017-06-06

    A number of studies have reported on the prognostic role of CD147 expression in non-small cell lung cancer (NSCLC); however, the results remain controversial. This study aims to investigate the impact of CD147 on the prognosis of NSCLC by means of a meta-analysis. A literature search was performed for relevant studies published before October 29, 2016. The hazard ratios (HRs), odds ratios (ORs), and 95% confidence intervals (CIs) were calculated as effective measures. Sensitivity analysis and publication bias examination were also conducted. Ten eligible studies with a total of 1605 patients were included in this meta-analysis. CD147 overexpression was correlated with poor overall survival (OS) (HR=1.59, 95% CI=1.32-1.91, pCD147 expression was associated with the presence of lymph node metastasis (OR=2.31, 95% CI=1.74-3.07, pCD147 and sex, age, differentiation, or histology was found. No evidence of significant publication bias was identified. This meta-analysis revealed that overexpression of CD147 was associated with shorter OS, the presence of lymph node metastasis and advanced TNM stage in NSCLC. Therefore, CD147 could serve as a potential prognostic marker for NSCLC.

  14. Access to Electric Light Is Associated with Shorter Sleep Duration in a Traditionally Hunter-Gatherer Community.

    Science.gov (United States)

    de la Iglesia, Horacio O; Fernández-Duque, Eduardo; Golombek, Diego A; Lanza, Norberto; Duffy, Jeanne F; Czeisler, Charles A; Valeggia, Claudia R

    2015-08-01

    Access to electric light might have shifted the ancestral timing and duration of human sleep. To test this hypothesis, we studied two communities of the historically hunter-gatherer indigenous Toba/Qom in the Argentinean Chaco. These communities share the same ethnic and sociocultural background, but one has free access to electricity while the other relies exclusively on natural light. We fitted participants in each community with wrist activity data loggers to assess their sleep-wake cycles during one week in the summer and one week in the winter. During the summer, participants with access to electricity had a tendency to a shorter daily sleep bout (43 ± 21 min) than those living under natural light conditions. This difference was due to a later daily bedtime and sleep onset in the community with electricity, but a similar sleep offset and rise time in both communities. In the winter, participants without access to electricity slept longer (56 ± 17 min) than those with access to electricity, and this was also related to earlier bedtimes and sleep onsets than participants in the community with electricity. In both communities, daily sleep duration was longer during the winter than during the summer. Our field study supports the notion that access to inexpensive sources of artificial light and the ability to create artificially lit environments must have been key factors in reducing sleep in industrialized human societies. © 2015 The Author(s).

  15. Dyslexics' faster decay of implicit memory for sounds and words is manifested in their shorter neural adaptation.

    Science.gov (United States)

    Jaffe-Dax, Sagi; Frenkel, Or; Ahissar, Merav

    2017-01-24

    Dyslexia is a prevalent reading disability whose underlying mechanisms are still disputed. We studied the neural mechanisms underlying dyslexia using a simple frequency-discrimination task. Though participants were asked to compare the two tones in each trial, implicit memory of previous trials affected their responses. We hypothesized that implicit memory decays faster among dyslexics. We tested this by increasing the temporal intervals between consecutive trials, and by measuring the behavioral impact and ERP responses from the auditory cortex. Dyslexics showed a faster decay of implicit memory effects on both measures, with similar time constants. Finally, faster decay of implicit memory also characterized the impact of sound regularities in benefitting dyslexics' oral reading rate. Their benefit decreased faster as a function of the time interval from the previous reading of the same non-word. We propose that dyslexics' shorter neural adaptation paradoxically accounts for their longer reading times, since it reduces their temporal window of integration of past stimuli, resulting in noisier and less reliable predictions for both simple and complex stimuli. Less reliable predictions limit their acquisition of reading expertise.

  16. Shorter duration of non-rapid eye movement sleep slow waves in EphA4 knockout mice.

    Science.gov (United States)

    Freyburger, Marlène; Poirier, Gaétan; Carrier, Julie; Mongrain, Valérie

    2017-10-01

    Slow waves occurring during non-rapid eye movement sleep have been associated with neurobehavioural performance and memory. In addition, the duration of previous wakefulness and sleep impacts characteristics of these slow waves. However, molecular mechanisms regulating the dynamics of slow-wave characteristics remain poorly understood. The EphA4 receptor regulates glutamatergic transmission and synaptic plasticity, which have both been linked to sleep slow waves. To investigate if EphA4 regulates slow-wave characteristics during non-rapid eye movement sleep, we compared individual parameters of slow waves between EphA4 knockout mice and wild-type littermates under baseline conditions and after a 6-h sleep deprivation. We observed that, compared with wild-type mice, knockout mice display a shorter duration of positive and negative phases of slow waves under baseline conditions and after sleep deprivation. However, the mutation did not change slow-wave density, amplitude and slope, and did not affect the sleep deprivation-dependent changes in slow-wave characteristics, suggesting that EphA4 is not involved in the response to elevated sleep pressure. Our present findings suggest a role for EphA4 in shaping cortical oscillations during sleep that is independent from sleep need. © 2017 European Sleep Research Society.

  17. Cleavage of SNAP25 and its shorter versions by the protease domain of serotype A botulinum neurotoxin.

    Directory of Open Access Journals (Sweden)

    Rahman M Mizanur

    Full Text Available Various substrates, catalysts, and assay methods are currently used to screen inhibitors for their effect on the proteolytic activity of botulinum neurotoxin. As a result, significant variation exists in the reported results. Recently, we found that one source of variation was the use of various catalysts, and have therefore evaluated its three forms. In this paper, we characterize three substrates under near uniform reaction conditions using the most active catalytic form of the toxin. Bovine serum albumin at varying optimum concentrations stimulated enzymatic activity with all three substrates. Sodium chloride had a stimulating effect on the full length synaptosomal-associated protein of 25 kDa (SNAP25 and its 66-mer substrates but had an inhibitory effect on the 17-mer substrate. We found that under optimum conditions, full length SNAP25 was a better substrate than its shorter 66-mer or 17-mer forms both in terms of kcat, Km, and catalytic efficiency kcat/Km. Assay times greater than 15 min introduced large variations and significantly reduced the catalytic efficiency. In addition to characterizing the three substrates, our results identify potential sources of variations in previous published results, and underscore the importance of using well-defined reaction components and assay conditions.

  18. Shorter time since inflammatory bowel disease diagnosis in children is associated with lower mental health in parents.

    Science.gov (United States)

    Werner, H; Braegger, Cp; Buehr, P; Koller, R; Nydegger, A; Spalinger, J; Heyland, K; Schibli, S; Landolt, Ma

    2015-01-01

    This study assessed the mental health of parents of children with inflammatory bowel disease (IBD), compared their mental health with age-matched and gender-matched references and examined parental and child predictors for mental health problems. A total of 125 mothers and 106 fathers of 125 children with active and inactive IBD from the Swiss IBD multicentre cohort study were included. Parental mental health was assessed by the Symptom Checklist 27 and child behaviour problems by the Strengths and Difficulties Questionnaire. Child medical data were extracted from hospital records. While the mothers reported lower mental health, the fathers' mental health was similar, or even better, than in age-matched and gender-matched community controls. In both parents, shorter time since the child's diagnosis was associated with poorer mental health. In addition, the presence of their own IBD diagnosis and child behaviour problems predicted maternal mental health problems. Parents of children with IBD may need professional support when their child is diagnosed, to mitigate distress. This, in turn, may help the child to adjust better to IBD. Particular attention should be paid to mothers who have their own IBD diagnosis and whose children display behaviour problems. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  19. Routine environmental monitoring schedule, calendar year 1997

    Energy Technology Data Exchange (ETDEWEB)

    Markes, B.M., Westinghouse Hanford

    1996-12-10

    This document provides the Environmental Restorations Contractor (ERC) and the Project Hanford Management Contractor.(PHMC) a schedule in accordance with the WHC-CM-7-5, Environmental Compliance` and BHI- EE-02, Environmental Requirements, of monitoring and sampling routines for the Near-Field Monitoring (NFM) program during calendar year (CY) 1997. Every attempt will be made to consistently follow this schedule; any deviation from this schedule will be documented by an internal memorandum (DSI) explaining the reason for the deviation. The DSI will be issued by the scheduled performing organization and directed to Near-Field Monitoring. The survey frequencies for particular sites are determined by the technical judgment of Near- Field Monitoring and may depend on the site history, radiological status, use, and general conditions. Additional surveys may be requested at irregular frequencies if conditions warrant. All radioactive wastes sites are scheduled to be surveyed at least annually. Any newly discovered wastes sites not documented by this schedule will be included in the revised schedule for CY 1998. The outside perimeter road surveys of 200 East and West Area and the rail survey from the 300 Area to Columbia Center will be performed in the year 2000 per agreement with Department of Energy. Richland Field Office. This schedule does not discuss staffing needs, nor does it list the monitoring equipment to be used in completing specific routines. Personnel performing routines to meet this schedule shall communicate any need for assistance in completing these routines to Radiological Control management and Near-Field Monitoring. After each routine survey is completed, a copy of the survey record, maps, and data sheets will be forwarded to Near-Field Monitoring. These routine surveys will not be considered complete until this documentation is received. At the end of each month, the ERC and PHMC radiological control organizations shall forward a copy of the Routine

  20. Shorter Versus Longer Shift Durations to Mitigate Fatigue and Fatigue-Related Risks in Emergency Medical Services Personnel and Related Shift Workers: A Systematic Review

    Science.gov (United States)

    2018-01-11

    Background: This study comprehensively reviewed the literature on the impact of shorter versus longer shifts on critical and important outcomes for Emergency Medical Services (EMS) personnel and related shift worker groups. Methods: Six databases (e....

  1. SHORTER, Aylward. African recruits and missionary conscripts: the White Fathers and the Great War (1914 – 1922. London: Missionaries of Africa History Project, 2007. 270 p. ISBN: 9780955523502

    Directory of Open Access Journals (Sweden)

    Jefferson Olivatto da Silva

    2011-09-01

    Full Text Available Resenha do livroSHORTER, Aylward. African recruits and missionary conscripts: the White Fathers and the Great War (1914 – 1922. London: Missionaries of Africa History Project, 2007. 270 p. ISBN: 9780955523502

  2. FOREST HARVEST SCHEDULING PLAN INTEGRATED TO THE ROAD NETWORK

    Directory of Open Access Journals (Sweden)

    Pedro Henrique Belavenutti Martins da Silva

    2016-03-01

    Full Text Available In industrial forest plantations, the spatial distribution of management units for harvest scheduling influences the timber production cost and the non-renewable resources consumption, due to issues related to transport logistic. In this context, this research aimed to formulate Integer Linear Programming (ILP by means of the application of Floyd-Warshall network optimization algorithm to generate timber production routes, minimizing the production costs resulting from harvest activities and forest road maintenance. Then, scenarios were simulated considering different minimal harvest ages for Pinus spp. and Eucalyptus spp. stands. The planning horizon was five years with annual periodicity. The study area was 23,330 hectares of forests, located in Paraná state (southern Brazil. We compared the simulated scenarios according to the following parameter indicators: harvest income, building road network and the production unit cost. The decreasing of the minimal harvest age reduces the mean production of management units scheduled to be harvested, in other hand, it requires fewer roads to be built, and consequently increases the production unit cost. The solutions obtained by using ILP models presented an optimality gap lower than 0.1%.

  3. An Improved Genetic Algorithm for Single-Machine Inverse Scheduling Problem

    Directory of Open Access Journals (Sweden)

    Jianhui Mou

    2014-01-01

    Full Text Available The goal of the scheduling is to arrange operations on suitable machines with optimal sequence for corresponding objectives. In order to meet market requirements, scheduling systems must own enough flexibility against uncertain events. These events can change production status or processing parameters, even causing the original schedule to no longer be optimal or even to be infeasible. Traditional scheduling strategies, however, cannot cope with these cases. Therefore, a new idea of scheduling called inverse scheduling has been proposed. In this paper, the inverse scheduling with weighted completion time (SMISP is considered in a single-machine shop environment. In this paper, an improved genetic algorithm (IGA with a local searching strategy is proposed. To improve the performance of IGA, efficient encoding scheme, fitness evaluation mechanism, feasible initialization methods, and a local search procedure have been employed in the paper. Because of the local improving method, the proposed IGA can balance its exploration ability and exploitation ability. We adopt 27 instances to verify the effectiveness of the proposed algorithm. The experimental results illustrated that the proposed algorithm can generate satisfactory solutions. This approach also has been applied to solve the scheduling problem in the real Chinese shipyard and can bring some benefits.

  4. The comparison of predictive scheduling algorithms for different sizes of job shop scheduling problems

    Science.gov (United States)

    Paprocka, I.; Kempa, W. M.; Grabowik, C.; Kalinowski, K.; Krenczyk, D.

    2016-08-01

    In the paper a survey of predictive and reactive scheduling methods is done in order to evaluate how the ability of prediction of reliability characteristics influences over robustness criteria. The most important reliability characteristics are: Mean Time to Failure, Mean Time of Repair. Survey analysis is done for a job shop scheduling problem. The paper answers the question: what method generates robust schedules in the case of a bottleneck failure occurrence before, at the beginning of planned maintenance actions or after planned maintenance actions? Efficiency of predictive schedules is evaluated using criteria: makespan, total tardiness, flow time, idle time. Efficiency of reactive schedules is evaluated using: solution robustness criterion and quality robustness criterion. This paper is the continuation of the research conducted in the paper [1], where the survey of predictive and reactive scheduling methods is done only for small size scheduling problems.

  5. Task-specific shell for scheduling problems, ARES[sub TM]/SCH. Scheduling mondai muke task tokka shell ARES[sub TM]/SCH

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, S; Narimatsu, K [Toshiba Corp., Tokyo (Japan)

    1994-08-01

    An Expert System (ES) Shell (developed by Toshiba Corp.) which applies to the scheduling of production plan and operation plan is introduced. It describes that this tool is equipped with flowchart editor and constraint condition editor which mention the knowledge related to scheduling method, and that the former expresses scheduling procedure knowledge in the form of flowchart by combining basic tasks prepared beforehand, and the latter expresses constraint conditions which should be satisfied by the schedule, and knowledge related to the priority order which should be considered in-between in the form of IF-THEN Rule which is very close to Japanese. In addition, the knowledge is equipped with knowledge debugging system which conducts debugging while executing the knowledge. It adds that by using this tool, the manhour required for the development and maintenance of ES can be reduced considerably. 2 refs., 3 figs.

  6. Productivity

    DEFF Research Database (Denmark)

    Spring, Martin; Johnes, Geraint; Hald, Kim Sundtoft

    Productivity is increasingly critical for developed economies. It has always been important: as Paul Krugman puts it, “Productivity isn’t everything, but in the long run it is almost everything. A country’s ability to improve its standard of living over time depends almost entirely on its ability...... to raise its output per worker”(Krugman, 1994). Analyses of productivity have, by and large, been the preserve of economists. Operations Management (OM) is rooted in a similar concern for the efficient use of scarce resources; Management Accounting (MA) is concerned with the institutionalised measurement...... and management of productivity. Yet the three perspectives are rarely connected. This paper is a sketch of a literature review seeking to identify, contrast and reconcile these three perspectives. In so doing, it aims to strengthen the connections between policy and managerial analyses of productivity....

  7. Clinch River Breeder Reactor Plant Project: construction schedule

    International Nuclear Information System (INIS)

    Purcell, W.J.; Martin, E.M.; Shivley, J.M.

    1982-01-01

    The construction schedule for the Clinch River Breeder Reactor Plant and its evolution are described. The initial schedule basis, changes necessitated by the evaluation of the overall plant design, and constructability improvements that have been effected to assure adherence to the schedule are presented. The schedule structure and hierarchy are discussed, as are tools used to define, develop, and evaluate the schedule

  8. NRC comprehensive records disposition schedule. Revision 3

    International Nuclear Information System (INIS)

    1998-02-01

    Title 44 US Code, ''Public Printing and Documents,'' regulations issued by the General Service Administration (GSA) in 41 CFR Chapter 101, Subchapter B, ''Management and Use of Information and Records,'' and regulations issued by the National Archives and Records Administration (NARA) in 36 CFR Chapter 12, Subchapter B, ''Records Management,'' require each agency to prepare and issue a comprehensive records disposition schedule that contains the NARA approved records disposition schedules for records unique to the agency and contains the NARA's General Records Schedules for records common to several or all agencies. The approved records disposition schedules specify the appropriate duration of retention and the final disposition for records created or maintained by the NRC. NUREG-0910, Rev. 3, contains ''NRC's Comprehensive Records Disposition Schedule,'' and the original authorized approved citation numbers issued by NARA. Rev. 3 incorporates NARA approved changes and additions to the NRC schedules that have been implemented since the last revision dated March, 1992, reflects recent organizational changes implemented at the NRC, and includes the latest version of NARA's General Records Schedule (dated August 1995)

  9. Schedule-Aware Workflow Management Systems

    Science.gov (United States)

    Mans, Ronny S.; Russell, Nick C.; van der Aalst, Wil M. P.; Moleman, Arnold J.; Bakker, Piet J. M.

    Contemporary workflow management systems offer work-items to users through specific work-lists. Users select the work-items they will perform without having a specific schedule in mind. However, in many environments work needs to be scheduled and performed at particular times. For example, in hospitals many work-items are linked to appointments, e.g., a doctor cannot perform surgery without reserving an operating theater and making sure that the patient is present. One of the problems when applying workflow technology in such domains is the lack of calendar-based scheduling support. In this paper, we present an approach that supports the seamless integration of unscheduled (flow) and scheduled (schedule) tasks. Using CPN Tools we have developed a specification and simulation model for schedule-aware workflow management systems. Based on this a system has been realized that uses YAWL, Microsoft Exchange Server 2007, Outlook, and a dedicated scheduling service. The approach is illustrated using a real-life case study at the AMC hospital in the Netherlands. In addition, we elaborate on the experiences obtained when developing and implementing a system of this scale using formal techniques.

  10. Mission Operations Planning and Scheduling System (MOPSS)

    Science.gov (United States)

    Wood, Terri; Hempel, Paul

    2011-01-01

    MOPSS is a generic framework that can be configured on the fly to support a wide range of planning and scheduling applications. It is currently used to support seven missions at Goddard Space Flight Center (GSFC) in roles that include science planning, mission planning, and real-time control. Prior to MOPSS, each spacecraft project built its own planning and scheduling capability to plan satellite activities and communications and to create the commands to be uplinked to the spacecraft. This approach required creating a data repository for storing planning and scheduling information, building user interfaces to display data, generating needed scheduling algorithms, and implementing customized external interfaces. Complex scheduling problems that involved reacting to multiple variable situations were analyzed manually. Operators then used the results to add commands to the schedule. Each architecture was unique to specific satellite requirements. MOPSS is an expert system that automates mission operations and frees the flight operations team to concentrate on critical activities. It is easily reconfigured by the flight operations team as the mission evolves. The heart of the system is a custom object-oriented data layer mapped onto an Oracle relational database. The combination of these two technologies allows a user or system engineer to capture any type of scheduling or planning data in the system's generic data storage via a GUI.

  11. Scheduling multimedia services in cloud computing environment

    Science.gov (United States)

    Liu, Yunchang; Li, Chunlin; Luo, Youlong; Shao, Yanling; Zhang, Jing

    2018-02-01

    Currently, security is a critical factor for multimedia services running in the cloud computing environment. As an effective mechanism, trust can improve security level and mitigate attacks within cloud computing environments. Unfortunately, existing scheduling strategy for multimedia service in the cloud computing environment do not integrate trust mechanism when making scheduling decisions. In this paper, we propose a scheduling scheme for multimedia services in multi clouds. At first, a novel scheduling architecture is presented. Then, We build a trust model including both subjective trust and objective trust to evaluate the trust degree of multimedia service providers. By employing Bayesian theory, the subjective trust degree between multimedia service providers and users is obtained. According to the attributes of QoS, the objective trust degree of multimedia service providers is calculated. Finally, a scheduling algorithm integrating trust of entities is proposed by considering the deadline, cost and trust requirements of multimedia services. The scheduling algorithm heuristically hunts for reasonable resource allocations and satisfies the requirement of trust and meets deadlines for the multimedia services. Detailed simulated experiments demonstrate the effectiveness and feasibility of the proposed trust scheduling scheme.

  12. MEDICAL STAFF SCHEDULING USING SIMULATED ANNEALING

    Directory of Open Access Journals (Sweden)

    Ladislav Rosocha

    2015-07-01

    Full Text Available Purpose: The efficiency of medical staff is a fundamental feature of healthcare facilities quality. Therefore the better implementation of their preferences into the scheduling problem might not only rise the work-life balance of doctors and nurses, but also may result into better patient care. This paper focuses on optimization of medical staff preferences considering the scheduling problem.Methodology/Approach: We propose a medical staff scheduling algorithm based on simulated annealing, a well-known method from statistical thermodynamics. We define hard constraints, which are linked to legal and working regulations, and minimize the violations of soft constraints, which are related to the quality of work, psychic, and work-life balance of staff.Findings: On a sample of 60 physicians and nurses from gynecology department we generated monthly schedules and optimized their preferences in terms of soft constraints. Our results indicate that the final value of objective function optimized by proposed algorithm is more than 18-times better in violations of soft constraints than initially generated random schedule that satisfied hard constraints.Research Limitation/implication: Even though the global optimality of final outcome is not guaranteed, desirable solutionwas obtained in reasonable time. Originality/Value of paper: We show that designed algorithm is able to successfully generate schedules regarding hard and soft constraints. Moreover, presented method is significantly faster than standard schedule generation and is able to effectively reschedule due to the local neighborhood search characteristics of simulated annealing.

  13. Scheduling nurses’ shifts at PGI Cikini Hospital

    Science.gov (United States)

    Nainggolan, J. C. T.; Kusumastuti, R. D.

    2018-03-01

    Hospitals play an essential role in the community by providing medical services to the public. In order to provide high quality medical services, hospitals must manage their resources (including nurses) effectively and efficiently. Scheduling of nurses’ work shifts, in particular, is crucial, and must be conducted carefully to ensure availability and fairness. This research discusses the job scheduling system for nurses in PGI Cikini Hospital, Jakarta with Goal Programming approach. The research objectives are to identify nurse scheduling criteria and find the best schedule that can meet the criteria. The model has hospital regulations (including government regulations) as hard constraints, and nurses’ preferences as soft constraints. We gather primary data (hospital regulations and nurses’ preferences) through interviews with three Head Nurses and distributing questionnaires to fifty nurses. The results show that on the best schedule, all hard constraints can be satisfied. However, only two out of four soft constraints are satisfied. Compared to current scheduling practice, the resulting schedule ensures the availability of nurses as it satisfies all hospital’s regulations and it has a higher level of fairness as it can accommodate some of the nurses’ preferences.

  14. PROMSYS, Plant Equipment Maintenance and Inspection Scheduling

    International Nuclear Information System (INIS)

    Morgan, D.L.; Srite, B.E.

    1986-01-01

    1 - Description of problem or function: PROMSYS is a computer system designed to automate the scheduling of routine maintenance and inspection of plant equipment. This 'programmed maintenance' provides the detailed planning and accomplishment of lubrication, inspection, and similar repetitive maintenance activities which can be scheduled at specified predetermined intervals throughout the year. The equipment items included are the typical pumps, blowers, motors, compressors, automotive equipment, refrigeration units, filtering systems, machine shop equipment, cranes, elevators, motor-generator sets, and electrical switchgear found throughout industry, as well as cell ventilation, shielding, containment, and material handling equipment unique to nuclear research and development facilities. Four related programs are used to produce sorted schedule lists, delinquent work lists, and optional master lists. Five additional programs are used to create and maintain records of all scheduled and unscheduled maintenance history. 2 - Method of solution: Service specifications and frequency are established and stored. The computer program reviews schedules weekly and prints, on schedule cards, instructions for service that is due the following week. The basic output from the computer program comes in two forms: programmed-maintenance schedule cards and programmed-maintenance data sheets. The data sheets can be issued in numerical building, route, and location number sequence as equipment lists, grouped for work assigned to a particular foreman as the foreman's equipment list, or grouped by work charged to a particular work order as the work-order list. Data sheets grouped by equipment classification are called the equipment classification list

  15. NRC comprehensive records disposition schedule. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    Title 44 US Code, ``Public Printing and Documents,`` regulations issued by the General Service Administration (GSA) in 41 CFR Chapter 101, Subchapter B, ``Management and Use of Information and Records,`` and regulations issued by the National Archives and Records Administration (NARA) in 36 CFR Chapter 12, Subchapter B, ``Records Management,`` require each agency to prepare and issue a comprehensive records disposition schedule that contains the NARA approved records disposition schedules for records unique to the agency and contains the NARA`s General Records Schedules for records common to several or all agencies. The approved records disposition schedules specify the appropriate duration of retention and the final disposition for records created or maintained by the NRC. NUREG-0910, Rev. 3, contains ``NRC`s Comprehensive Records Disposition Schedule,`` and the original authorized approved citation numbers issued by NARA. Rev. 3 incorporates NARA approved changes and additions to the NRC schedules that have been implemented since the last revision dated March, 1992, reflects recent organizational changes implemented at the NRC, and includes the latest version of NARA`s General Records Schedule (dated August 1995).

  16. Short-term scheduling of an open-pit mine with multiple objectives

    Science.gov (United States)

    Blom, Michelle; Pearce, Adrian R.; Stuckey, Peter J.

    2017-05-01

    This article presents a novel algorithm for the generation of multiple short-term production schedules for an open-pit mine, in which several objectives, of varying priority, characterize the quality of each solution. A short-term schedule selects regions of a mine site, known as 'blocks', to be extracted in each week of a planning horizon (typically spanning 13 weeks). Existing tools for constructing these schedules use greedy heuristics, with little optimization. To construct a single schedule in which infrastructure is sufficiently utilized, with production grades consistently close to a desired target, a planner must often run these heuristics many times, adjusting parameters after each iteration. A planner's intuition and experience can evaluate the relative quality and mineability of different schedules in a way that is difficult to automate. Of interest to a short-term planner is the generation of multiple schedules, extracting available ore and waste in varying sequences, which can then be manually compared. This article presents a tool in which multiple, diverse, short-term schedules are constructed, meeting a range of common objectives without the need for iterative parameter adjustment.

  17. IRRIGATION SCHEDULING CALCULATOR (ISC TO IMPROVE WATER MANAGEMENT ON FIELD LEVEL IN EGYPT

    Directory of Open Access Journals (Sweden)

    Samiha Abou El-Fetouh Hamed Ouda

    2017-10-01

    Full Text Available The developed model is MS excel sheet called “Irrigation Scheduling Calculator, ISC”. The model requires to input daily weather data to calculate daily evapotranspiration using Penman-Monteith equation. The model calculates water depletion from the root zone to determine when to irrigate and how much water should be applied. The charge from irrigation pump is used to calculate how many hours should the farmer run the pump to deliver the needed amount of water. ISC model was used to developed irrigation schedule for wheat and maize planted in El-Gharbia governorate. The developed schedules were compared to the actual schedules for both crops. Furthermore, CropSyst model was calibrated for both crops and run using the developed schedules by ISC model. The simulation results indicated that the calculated irrigation amount by ISC model for wheat was lower than actual schedule by 6.0 mm. Furthermore, the simulated wheat productivity by CropSyst was higher than measured grain and biological by 2%. Similarly, the calculated applied irrigation amount by ISC model for maize was lower than actual schedule by 79.0 mm and the productivity was not changed.

  18. Feasibility of a shorter Goal Attainment Scaling method for a pediatric spasticity clinic - The 3-milestones GAS.

    Science.gov (United States)

    Krasny-Pacini, A; Pauly, F; Hiebel, J; Godon, S; Isner-Horobeti, M-E; Chevignard, M

    2017-07-01

    Goal Attainment Scaling (GAS) is a method for writing personalized evaluation scales to quantify progress toward defined goals. It is useful in rehabilitation but is hampered by the experience required to adequately "predict" the possible outcomes relating to a particular goal before treatment and the time needed to describe all 5 levels of the scale. Here we aimed to investigate the feasibility of using GAS in a clinical setting of a pediatric spasticity clinic with a shorter method, the "3-milestones" GAS (goal setting with 3 levels and goal rating with the classical 5 levels). Secondary aims were to (1) analyze the types of goals children's therapists set for botulinum toxin treatment and (2) compare the score distribution (and therefore the ability to predict outcome) by goal type. Therapists were trained in GAS writing and prepared GAS scales in the regional spasticity-management clinic they attended with their patients and families. The study included all GAS scales written during a 2-year period. GAS score distribution across the 5 GAS levels was examined to assess whether the therapist could reliably predict outcome and whether the 3-milestones GAS yielded similar distributions as the original GAS method. In total, 541 GAS scales were written and showed the expected score distribution. Most scales (55%) referred to movement quality goals and fewer (29%) to family goals and activity domains. The 3-milestones GAS method was feasible within the time constraints of the spasticity clinic and could be used by local therapists in cooperation with the hospital team. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  19. Psoralen-mediated virus photoinactivation in platelet concentrates: enhanced specificity of virus kill in the absence of shorter UVA wavelengths

    International Nuclear Information System (INIS)

    Margolis-Nunno, Henrietta; Robinson, Richard; Horowitz, Bernard; Ben-Hur, Ehud; Geacintov, N.E.

    1995-01-01

    Treatments with psoralens and long-wavelength ultraviolet radiation (UVA, 320-400 nm; PUVA) have shown efficacy for virus sterilization of platelet concentrates (PC). We have employed the psoralen derivative 4'-aminomethyl-4,5',8-trimethylpsoralen (AMT), and have found that platelet integrity is best preserved when rutin, a flavonoid that quenches multiple reactive oxygen species, is present during AMT/UVA treatment of PC. In this report, we examine the effects of different UVA spectra under our standard PC treatment conditions (i.e. 50 μg/mL AMT, 0.35 mM rutin and 38 J/cm 2 UVA). Added vesicular stomatitis virus (VSV; ≥ 5.5 log 10 ) was completely inactivated with the simultaneous maintenance of the platelet aggregation response (> 90% of control) when a UVA light source with transmission mainly between 360 and 370 nm (narrow UVA1) was used. In contrast, with a broad-band UVA (320-400 nm; broad UVA) light source, the aggregation response was greatly compromised (< 50% of control) with only a minor increase in the rate of VSV kill. With this lamp, platelet function could be improved to about 75% of the control by adding a long-pass filter, which reduced the transmission of shorter (≤ 345 nm) UVA wavelengths (340-400 nm; UVA1). At equivalent levels of virus kill, aggregation function was always best preserved when narrow UVA1 was used for PUVA treatment. Even in the absence of AMT, and with or without rutin present, narrow UVA1 irradiation was better tolerated by platelets than was broad UVA. (author)

  20. Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones.

    Directory of Open Access Journals (Sweden)

    Kenta Saito

    Full Text Available TNFα-converting enzyme (TACE is a membrane-bound proteolytic enzyme with essential roles in the functional regulation of TNFα and epidermal growth factor receptor (EGFR ligands. Previous studies have demonstrated critical roles for TACE in vivo, including epidermal development, immune response, and pathological neoangiogenesis, among others. However, the potential contribution of TACE to skeletal development is still unclear. In the present study, we generated a Tace mutant mouse in which Tace is conditionally disrupted in chondrocytes under the control of the Col2a1 promoter. These mutant mice were fertile and viable but all exhibited long bones that were approximately 10% shorter compared to those of wild-type animals. Histological analyses revealed that Tace mutant mice exhibited a longer hypertrophic zone in the growth plate, and there were fewer osteoclasts at the chondro-osseous junction in the Tace mutant mice than in their wild-type littermates. Of note, we found an increase in osteoprotegerin transcripts and a reduction in Rankl and Mmp-13 transcripts in the TACE-deficient cartilage, indicating that dysregulation of these genes is causally related to the skeletal defects in the Tace mutant mice. Furthermore, we also found that phosphorylation of EGFR was significantly reduced in the cartilage tissue lacking TACE, and that suppression of EGFR signaling increases osteoprotegerin transcripts and reduces Rankl and Mmp-13 transcripts in primary chondrocytes. In accordance, chondrocyte-specific abrogation of Egfr in vivo resulted in skeletal defects nearly identical to those observed in the Tace mutant mice. Taken together, these data suggest that TACE-EGFR signaling in chondrocytes is involved in the turnover of the growth plate during postnatal development via the transcriptional regulation of osteoprotegerin, Rankl, and Mmp-13.