WorldWideScience

Sample records for shorter construction period

  1. 36 CFR 223.81 - Shorter advertising periods in emergencies.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Shorter advertising periods... OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER Timber Sale Contracts Advertisement and Bids § 223.81 Shorter advertising periods in emergencies. In emergency situations where prompt...

  2. 47 CFR 22.1035 - Construction period.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Construction period. 22.1035 Section 22.1035 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PUBLIC MOBILE SERVICES Offshore Radiotelephone Service § 22.1035 Construction period. The construction period (see § 22.142) for...

  3. Measuring single constructs by single items: Constructing an even shorter version of the "Short Five" personality inventory.

    Directory of Open Access Journals (Sweden)

    Kenn Konstabel

    Full Text Available The aim of this study was to construct a short, 30-item personality questionnaire that would be, in terms of content and meaning of the scores, as comparable as possible with longer, well-established inventories such as NEO PI-R and its clones. To do this, we shortened the formerly constructed 60-item "Short Five" (S5 by half so that each subscale would be represented by a single item. We compared all possibilities of selecting 30 items (preserving balanced keying within each domain of the five-factor model in terms of correlations with well-established scales, self-peer correlations, and clarity of meaning, and selected an optimal combination for each domain. The resulting shortened questionnaire, XS5, was compared to the original S5 using data from student samples in 6 different countries (Estonia, Finland, UK, Germany, Spain, and China, and a representative Finnish sample. The correlations between XS5 domain scales and their longer counterparts from well-established scales ranged from 0.74 to 0.84; the difference from the equivalent correlations for full version of S5 or from meta-analytic short-term dependability coefficients of NEO PI-R was not large. In terms of prediction of external criteria (emotional experience and self-reported behaviours, there were no important differences between XS5, S5, and the longer well-established scales. Controlling for acquiescence did not improve the prediction of criteria, self-peer correlations, or correlations with longer scales, but it did improve internal reliability and, in some analyses, comparability of the principal component structure. XS5 can be recommended as an economic measure of the five-factor model of personality at the level of domain scales; it has reasonable psychometric properties, fair correlations with longer well-established scales, and it can predict emotional experience and self-reported behaviours no worse than S5. When subscales are essential, we would still recommend using the

  4. Measuring single constructs by single items: Constructing an even shorter version of the “Short Five” personality inventory

    Science.gov (United States)

    Konstabel, Kenn; Lönnqvist, Jan-Erik; Leikas, Sointu; García Velázquez, Regina; Qin, Hiaying; Verkasalo, Markku; Walkowitz, Gari

    2017-01-01

    The aim of this study was to construct a short, 30-item personality questionnaire that would be, in terms of content and meaning of the scores, as comparable as possible with longer, well-established inventories such as NEO PI-R and its clones. To do this, we shortened the formerly constructed 60-item “Short Five” (S5) by half so that each subscale would be represented by a single item. We compared all possibilities of selecting 30 items (preserving balanced keying within each domain of the five-factor model) in terms of correlations with well-established scales, self-peer correlations, and clarity of meaning, and selected an optimal combination for each domain. The resulting shortened questionnaire, XS5, was compared to the original S5 using data from student samples in 6 different countries (Estonia, Finland, UK, Germany, Spain, and China), and a representative Finnish sample. The correlations between XS5 domain scales and their longer counterparts from well-established scales ranged from 0.74 to 0.84; the difference from the equivalent correlations for full version of S5 or from meta-analytic short-term dependability coefficients of NEO PI-R was not large. In terms of prediction of external criteria (emotional experience and self-reported behaviours), there were no important differences between XS5, S5, and the longer well-established scales. Controlling for acquiescence did not improve the prediction of criteria, self-peer correlations, or correlations with longer scales, but it did improve internal reliability and, in some analyses, comparability of the principal component structure. XS5 can be recommended as an economic measure of the five-factor model of personality at the level of domain scales; it has reasonable psychometric properties, fair correlations with longer well-established scales, and it can predict emotional experience and self-reported behaviours no worse than S5. When subscales are essential, we would still recommend using the full version

  5. Shortening of construction period of nuclear power plant. Activities of construction industry on construction period shortening

    International Nuclear Information System (INIS)

    Kamata, Hirofumi

    2011-01-01

    Total construction period could be shorten by prefabricating structures efficiently in another yard and reducing working hours on site, which would reduce work at height or congestion work and also upgrade safety at work. Construction period shortening would surely reduce expenses during work and advance operation start of electric utilities. Construction of reactor building, turbine building, water intake and drainage canal was performed on a relatively large scale and a big share of whole schedule. This article summarized basic technologies to shorten construction period for reactor building/turbine building and water intake and drainage canal. Advanced methods of reactor building/turbine building; (1) modularization of equipment and skeleton, (2) utilization of concrete mold, reinforcing bar and steel frame, (3) precedent steel frame method and (4) steel plate reinforced concrete (SC) method, were outlined and their application examples were shown to reduce work on site and improve work efficiency. As for water intake and drainage canal construction, (1) precast concrete method, (2) SC method and (3) steel plate shell method were described with application examples. Construction procedures and problems using mega block method for water intake and drainage canal were also introduced. (T. Tanaka)

  6. 47 CFR 73.3598 - Period of construction.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Period of construction. 73.3598 Section 73.3598 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES... size standards for its industry grouping, as set forth in 13 CFR 121 through 201, at the time the...

  7. Driving for shorter outages

    International Nuclear Information System (INIS)

    Tritch, S.

    1996-01-01

    Nuclear plant outages are necessary to complete activities that cannot be completed during the operating cycle, such as steam generator inspection and testing, refueling, installing modifications, and performing maintenance tests. The time devoted to performing outages is normally the largest contributor to plant unavailability. Similarly, outage costs are a sizable portion of the total plant budget. The scope and quality of work done during outages directly affects operating reliability and the number of unplanned outages. Improved management and planning of outages enhances the margin of safety during the outage and results in increased plant reliability. The detailed planning and in-depth preparation that has become a necessity for driving shorter outage durations has also produced safer outages and improved post-outage reliability. Short outages require both plant and vendor management to focus on all aspects of the outage. Short outage durations, such as 26 days at South Texas or 29 days at North Anna, require power plant inter-department and intra-department teamwork and communication and vendor participation. In this paper shorter and safer outage at the 3-loop plants in the United States are explained. (J.P.N.)

  8. Analysis on optimization of the critical path for civil construction period of Fangjiashan nuclear island constructed under EPC mode

    International Nuclear Information System (INIS)

    Liu Yongqing; Wu Youcong; Qiu Jinhong

    2011-01-01

    Based on the actual situation of nuclear island civil construction in Fangjiashan nuclear power plant and combined with the arrangement of the construction schedule, the analysis on optimization of the critical path for civil construction period is conducted. The result shows that on the premise of not increasing the contract price and the total engineering cost based on the original 57-month construction period, the construction period can be shorten to 21 month through strengthening the schedule control, keeping the critical work in a reasonable duration and rearranging the link between programmers. In addition, in view of the economic analysis, if we increase the mechanical engagement and adopt special method, the 2-month construction period can be even shortened to 20 months. (authors)

  9. LULA VS ALCKMIN: DISCURSIVE CONSTRUCTIONS OF THE VEJA PERIODIC

    Directory of Open Access Journals (Sweden)

    Cicília de Sousa Frazão

    2009-08-01

    Full Text Available This work is carried out an analysis of the cover of the 1980 edition of the magazine Veja, published on November 01, 2006, in the election campaign of 2006 – second round, focusing on the image of President Luiz Inácio Lula da Silva and Geraldo Alckmin. Try to understand the imagetic and verbal speech expressed in covers and its constraints on social and discursive formation, through the investigations of the mechanisms of construction of the iconic and verbal text and reveal the effects of meaning constructed in covers. Based on a theoretical support, to seek to understand of how the effect depends on the codes produced by a culture and how they are mobilized by the media to construct or deconstruct a politician´s image facing society

  10. Digital Technology for Construction Period Reduction of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    You, Y. M. [PHILOSOPHIA, Inc., Seoul (Korea, Republic of); Suh, K. Y. [Seoul National Univ., Seoul (Korea, Republic of)

    2009-10-15

    PHILOSOPHIA, Inc. and Seoul National University have jointly developed a first-of-a-kind engineering (FOAKE) solution. The solution lends itself to the four-plus-dimensional (4{sup +}D) Technology{sup TM} resorting to three -dimensional (3D) computer-aided design (CAD) digital mockup (DMU). The aim is to minimize the working hours via process optimization by real-time exchange of design and process information in the ubiquitous system. The 4{sup +}D Technology{sup TM} in the 3D virtual reality (VR) space and time plus cost coordinates, is developed to reduce the construction time as well as cost of nuclear power plants (NPPs) by optimizing the manufacturing procedure and construction process. The 4{sup +}D Technology{sup TM} anchored to the 3D CAD DMU allows the interference of the NPP components to be checked upon early in the design stage, and the process sequences to be optimized. Moreover, its ergonomic and robotic technologies enable simulation of all the aspects of the workers, robots and machines involved in the construction process. One of the greatest advantages of the 4{sup +}D Technology{sup TM} lies in that any change of the overall process procedures can virtually be tested. On the other hand, it shall financially be unbearable to alter the procedures consisting of plenty of structures and components, complicated detailed processes and long work hours in the physical space.

  11. Digital Technology for Construction Period Reduction of Nuclear Power Plants

    International Nuclear Information System (INIS)

    You, Y. M.; Suh, K. Y.

    2009-01-01

    PHILOSOPHIA, Inc. and Seoul National University have jointly developed a first-of-a-kind engineering (FOAKE) solution. The solution lends itself to the four-plus-dimensional (4 + D) Technology TM resorting to three -dimensional (3D) computer-aided design (CAD) digital mockup (DMU). The aim is to minimize the working hours via process optimization by real-time exchange of design and process information in the ubiquitous system. The 4 + D Technology TM in the 3D virtual reality (VR) space and time plus cost coordinates, is developed to reduce the construction time as well as cost of nuclear power plants (NPPs) by optimizing the manufacturing procedure and construction process. The 4 + D Technology TM anchored to the 3D CAD DMU allows the interference of the NPP components to be checked upon early in the design stage, and the process sequences to be optimized. Moreover, its ergonomic and robotic technologies enable simulation of all the aspects of the workers, robots and machines involved in the construction process. One of the greatest advantages of the 4 + D Technology TM lies in that any change of the overall process procedures can virtually be tested. On the other hand, it shall financially be unbearable to alter the procedures consisting of plenty of structures and components, complicated detailed processes and long work hours in the physical space

  12. Development of advanced concept for shortening construction period of ABWR plant (part 2)

    International Nuclear Information System (INIS)

    Fujita, Tomohiro; Satoh, Takashi

    2003-01-01

    The construction of the first building fully applying SC structure, which is indispensable for shortening construction period of ABWR plants (21.5 months from the first concrete work to fuel loading), has been started since August 2002 in Japan. Before the construction start, a pre-construction test with some actual size SC panels was carried out to confirm the SC modular construction method. The outline of the design and the construction of the first full-SC building and the results of the pre-construction test are reported. (author)

  13. Development of Advanced Concept for Shortening Construction Period of ABWR Plant

    International Nuclear Information System (INIS)

    Hiroshi Ijichi; Toshio Yamashita; Masahiro Tsutagawa; Hiroya Mori; Nobuaki Ooshima; Jun Miura; Minoru Kanechika; Nobuaki Miura

    2002-01-01

    Construction of a nuclear power plant (NPP) requires a very long period because of large amount of construction materials and many issues for negotiation among multiple sections. Shortening the construction period advances the date of return on an investment, and can also result in reduced construction cost. Therefore, the study of this subject has a very high priority for utilities. We achieved a construction period of 37 months from the first concrete work to fuel loading (F/L) (51.5 months from the inspection of the foundation (I/F) to the start of commercial operation (C/O)) at the Kashiwazaki-Kariwa NPPs No. 6 and 7 (KK-6/7), which are the first ABWR plants in the world. At TEPCO's next plant, we think that a construction period of less than 36 months (45 months from I/F to C/O) can be realized based on conventional methods such as early start of equipment installation and blocking of equipment to be brought in advance. Furthermore, we are studying the feasibility of a 21.5-month construction period (30 months from I/F to C/O) with advanced ideas and methods. The important concepts for a 21.5-month construction period are adoption of a new building structure that is the steel plate reinforced concrete (SC) structure and promotion of extensive modularization of equipment and building structure. With introducing these new concepts, we are planning the master schedule (M/S) and finding solutions to conflicts in the schedule of area release from building construction work to equipment installation work (schedule-conflicts.) In this report, we present the shortest construction period and an effective method to put it into practice for the conventional general arrangement (GA) of ABWR. In the future, we will continue the study on the improvement of building configuration and arrangements, and make clear of the concept for large composite modules of building structures and equipment. (authors)

  14. Reduction of construction periods of PWRs by optimization of detailed sequence planning

    International Nuclear Information System (INIS)

    Stocker, W.; Leverenz, R.

    1991-01-01

    The construction of PWR's is an enterprise with high investment costs, in total up to three billion US$ and with long construction periods of five years and more. Besides the results reached by the intensive standardization, a further reduction of the construction period is possible by optimization of detailed sequence planning and interfaces of work units. During the execution of the three German Convoy plants ISAR 2, EMSLAND and NECKARWESTHEIM 2, the contractual construction periods were shortened between 4 and 8 months. These reductions were reached after individual investigations by measures like advanced finishing work activities; erection of an increased amount of prefabricated pipings; rearrangement of erection sequences; overlapping of piping erection and electrical installation; reduction of plant commissioning period. All these measures support directly the reduction of the total investment cost of a plant, as already demonstrated by the Convoy plants. (author). 8 figs

  15. 47 CFR 25.133 - Period of construction; certification of commencement of operation.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Period of construction; certification of commencement of operation. 25.133 Section 25.133 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Applications and Licenses Earth Stations § 25.133 Period...

  16. Methods for reduction of the period for construction and commissioning of NPP

    International Nuclear Information System (INIS)

    Bogdanov, D.

    2004-01-01

    The process of construction of NPP unit is associated with significant amount of engineering, civil construction works, equipment installation and testing works. In order to achieve better economical results from the point of view of the investor, it will be a benefit if the time period for construction and commissioning of the unit is reduced. In order to realize such reduction of the needed time it is possible to utilize some new approaches for installation of heavy equipment, utilization of prefabricated in advance composite modules of equipment and application of new types of construction equipment and techniques. In such way the commissioning period can be reduced, and high quality of the installation works can be achieved. (author)

  17. A study on the competitiveness improvement of the OPR1000 through reduction of the construction period

    International Nuclear Information System (INIS)

    Lee, Deuck Soo

    2009-02-01

    Current world's nuclear power plant markets change will provide variety opportunities to the Korean nuclear power plant industries. The economic competitiveness is the most significant issue to utilize the forthcoming 'Renaissance of Nuclear Power' as a chance of exporting OPR1000. To improve the competitiveness of the OPR1000, the capital cost which is the key factor of the generating cost of the nuclear power plant should be reduced. Reduction of the construction period is more important than the design improvement or facility change regarding capital cost perspectives. The aim of this study, therefore, is to introduce the parallel installation method for reducing the construction period to achieve the economic competitiveness. The parallel installation path was selected among critical paths by analyzing the construction schedules of the nuclear power plants built in Korea. Reactor Coolant Loop Installation and Reactor Vessel Internal Installation were selected for the parallel installation method in this study. Conventional installation method installs reactor vessel internal after finishing reactor coolant loop installation. Therefore it needs about twenty (20) months from the reactor vessel settings to the completion of the reactor vessel internal installation. The parallel installation methodology proposed in this study can reduce the construction period about two (2) months by installing reactor vessel internals in parallel with the welding process of the cross-over leg between the steam generator and the reactor coolant pump. ANSYS Codes was utilized to show the deformation impacts on the reactor vessel caused by the shrinkage force imposed by the welding process of the cross-over leg. The code analysis results lead the deformation impact is negligible. And it confirms the parallel installation of the reactor vessel internal with the cross-over leg can be applied for the OPR1000 construction. The economic improvement by the parallel installation was also

  18. EVALUATION OF PRODUCTION IN SEASONALITY PERIODS: ANALYSIS OF THE CONSTRUCTION INDUSTRY IN BRAZIL

    Directory of Open Access Journals (Sweden)

    Marcos William Kaspchak Machado

    2013-06-01

    Full Text Available The present work has as an objective to evaluate the impacts of production seasonality in seasonality periods in the Brazilian construction industry. The adopted methodology was based on the qualitative and quantitative approaches of the aspects inherent to the seasonality factors in the construction industry and its possible causes. Besides that, literature data were collected in year report books and devices provided by institutions of the sector. The results demonstrated the importance of production management mechanisms to optimize the use of productive factors through cost analysis, which are fundamental to understand the operational flux of resources used in the operational media. Obtaining this information, connected to market indicators helped in the decision making process related to the development of prospective scenarios which will give support to the decision making strategy aiming to stabilize the production levels.

  19. Prediction of the period of psychotic episode in individual schizophrenics by simulation-data construction approach.

    Science.gov (United States)

    Huang, Chun-Jung; Wang, Hsiao-Fan; Chiu, Hsien-Jane; Lan, Tsuo-Hung; Hu, Tsung-Ming; Loh, El-Wui

    2010-10-01

    Although schizophrenia can be treated, most patients still experience inevitable psychotic episodes from time to time. Precautious actions can be taken if the next onset can be predicted. However, sufficient information is always lacking in the clinical scenario. A possible solution is to use the virtual data generated from limited of original data. Data construction method (DCM) has been shown to generate the virtual felt earthquake data effectively and used in the prediction of further events. Here we investigated the performance of DCM in deriving the membership functions and discrete-event simulations (DES) in predicting the period embracing the initiation and termination time-points of the next psychotic episode of 35 individual schizophrenic patients. The results showed that 21 subjects had a success of simulations (RSS) ≥70%. Further analysis demonstrated that the co-morbidity of coronary heart diseases (CHD), risks of CHD, and the frequency of previous psychotic episodes increased the RSS.

  20. Final construction of the C.R.E.O.L. 8 millimeter period hybrid undulator

    Energy Technology Data Exchange (ETDEWEB)

    Tesch, P.; Gallagher, J.; Elias, L. [Center for Research and Education in Optics and Lasers, Orlando, FL (United States)

    1995-12-31

    The construction of an 8 millimeter period hybrid undulator for the C.R.E.O.L. high power far-infared free electron laser has just been completed. This FEL is expected to come on-line in the fall of 1995 and produce close to a kilowatt of continuous power at wavelengths of 225 - 800 microns. The undulator has extremely precise mechanical tolerances and high field uniformity allowing for high electron beam recovery rates. Almost complete beam recovery is required for DC operation at high currents. A novel method for measuring the magnetic properties of individual magnets and sorting the magnets to reduce magnetic field errors will be reported. The peak field and phase errors of the undulator without the pole pieces are reduced through a magnet ordering procedure. These errors are further reduced by inserting and tuning adjustable pole pieces. The reduction of field errors through these two techniques will be presented. An analysis of the final undulator errors and the results of measurements of the mechanical tolerances will be presented.

  1. The perspectives of research in the construction field in Romania during the 2014-2020 period

    OpenAIRE

    Mihai VRABIE; Sergiu-Andrei BĂETU

    2013-01-01

    The construction field represents an important part of the Romanian economy (and of UE), with a strong social impact on the quality of citizen life. Naturally, the research from the construction field should be a priority in research and innovation activity. However, the research programs recently launched (Horizon 2020, from EU, and the Strategy of Research and Innovation 2014-2020 in Romania), don’t mention the construction field as an explicit priority. Under these conditions, we can speak...

  2. Construction of 2D quasi-periodic Rauzy tiling by similarity transformation

    International Nuclear Information System (INIS)

    Zhuravlev, V. G.; Maleev, A. V.

    2009-01-01

    A new approach to constructing self-similar fractal tilings is proposed based on the construction of semigroups generated by a finite set of similarity transformations. The Rauzy tiling-a 2D analog of 1D Fibonacci tiling generated by the golden mean-is used as an example to illustrate this approach. It is shown that the Rauzy torus development and the elementary fractal boundary of Rauzy tiling can be constructed in the form of a set of centers of similarity semigroups generated by two and three similarity transformations, respectively. A centrosymmetric tiling, locally dual to the Rauzy tiling, is constructed for the first time and its parameterization is developed.

  3. The history of the construction of main state irrigation systems in the postwar period

    Directory of Open Access Journals (Sweden)

    A. N. Chepurda

    2017-03-01

    It was established that the construction of large public irrigation systems in Ukraine started in 1951 stated that hydro construction that unfolded in the south of Ukraine, opened prospects to final elimination of the impact of drought and dry winds, the prospects for an unprecedented economic prosperity of the area.

  4. [Research on the hospital construction and structure in Daehan empire and colonial modern period].

    Science.gov (United States)

    Han, Dong Gwan; Ryu, Chang Ug; Ko, Sang Kyun; Jung, Jae Kook; Moon, Jong Youn; Park, Yoon Hyung

    2011-12-31

    It was the late Chosun Dynasty and Daehan Empire era that Western Medicine has firstly been introduced to Korea, previously operating on a basis of Korean traditional medicine. Western Medicine has been introduced by American missionary and Japanese Imperialism. An introduction of Western Medicine made it feasible to proceed new type medical care including operation, leading to require a new form of medical facilities. In the beginning, new facilities were constructed by Japanese Imperialism. Other hand many of facilities including Severance Hospital were established by missionaries. First of all, Daehan Empire established and managed a modern type of medical facility named "Jejoongwon" in 1885 as a government institution hospital. The Red Cross Hospital built in 1889. Afterwards, Jejoongwon and the Red Cross Hospital were taken over to missionary hospital and Japanese Imperialism, respectively. Japanese Imperialists firstly have protected their nationals residing in Chosun but have proceeded care a few Chosun people to exploit medical treatment as a mean to advertise superiority of the Empire of Japan. The facility that has firstly been established and managed was Jeseang Hospital in Busan in 1877, leading to establish in Wonju, Wonsan, and Mokpo. Afterwards, Japan has organized "Donginhoi" as a civil invasion organization, leading for "Donginhoi" to established "Dongin Hospital" in Pyeongyang, Daegu, and Seoul. Since 1909, governmental leading medical facility named Jahye Hospital was established according to an imperial order, leading to establish 32 hospitals all over the nation. American missionaries have established and managed 28 hospitals started from Severance Hospital built in 1904. However, Chosun doctors started to having educated and opening up their own hospital since 1920, leading for many of medical facilities to be established, but most of them have taken different roles followed by 6.25 War and economic development period. However, some of them

  5. The construction of periodic unfolding operators on some compact Riemannian manifolds

    DEFF Research Database (Denmark)

    Dobberschütz, Sören; Böhm, Michael

    2014-01-01

    The notion of periodic unfolding has become a standard tool in the theory of periodic homogenization. However, all the results obtained so far are only applicable to the "flat" Euclidean space R n. In this paper, we present a generalization of the method of periodic unfolding applicable to struct...

  6. Implications of shorter cells in PEP

    International Nuclear Information System (INIS)

    Wiedemann, H.

    1975-01-01

    Further studies on the beam-stay-clear requirements in PEP led to the conclusion that the vertical aperture needed to be enlarged. There are two main reasons for that: Observations at SPEAR indicate that the aperture should be large enough for a fully coupled beam. Full coupling of the horizontal and vertical betatron oscillations occurs not only occasionally when the energy, tune or betatron function at the interaction point is changed but also due to the beam/endash/beam effect of two strong colliding beams. The second reason for an increased aperture requirement is the nonlinear perturbation of the particle trajectories by the sextupoles. This perturbation increases a fully coupled beam by another 50% to 80%. Both effects together with a +-5 mm allowance for closed orbit perturbation result in a vertical beam-stay-clear in the bending magnets of +-4.8 to +-5.6 cm, compared to the present +-2.0 cm. This beam-stay-clear, together with additional space for vacuum chamber, etc., leads to very costly bending magnets. In this note, a shorter cell length is proposed which would reduce considerably the vertical beam-stay-clear requirements in the bending magnets. 7 figs

  7. Engineered barrier construction in salt rock. Final report of project phase 2. Period covered: 1 July 1989 - 31 December 1992

    International Nuclear Information System (INIS)

    Stockmann, N.; Beinlich, A.; Droste, J.; Flach, D.; Glaess, F.; Jockwer, N.; Krogmann, P.; Miehe, R.; Moeller, J.; Schwaegermann, F.; Wallmueller, R.; Walter, F.; Yaramanci, U.

    1994-01-01

    The project report presents and explains data obtained by a specific measuring programme, giving evidence of the sealing efficiency of an engineered barrier comprising abutment, long-term barrier, and hydraulic short-term barrier, the sealing performance having been verified for shorter and longer periods of time ( up to approx. 500 years). Specific computer codes have been applied for computing and verifying the long-term efficiency of the complex engineered barrier system (artificial structures and surrounding rock). The technical feasibility and the performance of an engineered barrier for reliable sealing of a radwaste repository is thus demonstrated at a scale of 1:1 at the site of the Asse mine [de

  8. Reduction of construction period by development and applying of advanced turbine generator foundation as composite structure

    International Nuclear Information System (INIS)

    Sekimoto, Hisashi; Fuyama, Hiroyuki; Kameda, Ichiro; Fukunaga, Yuuji; Umetada, Isao; Magoshi, Ryutaro

    1999-01-01

    Mitsubishi Heavy Industries developed a composite steel-concrete beam for constructing elevated horizontal beams for turbine-generator foundations. This system was used at the company's Verification Test Plant at the Takasago Machinery Works. Composite steel-concrete beams are made from U-shaped steel casings that acts as a temporarily formwork and are permanently used as major concrete beam reinforcement. Prefabricated U-shaped steel casings must be placed on top of vertical concrete columns. After steel casings are positioned and secured, concrete is filled. This technique cuts one month from construction time and simplifies required temporary work such as falsework and formwork. This paper details the results of practical research on design and construction as they relate to required strength and vibration. (author)

  9. Construction training process of highly skilled players in mini-football for competition period

    Directory of Open Access Journals (Sweden)

    Stasiuk I.I.

    2013-08-01

    Full Text Available Analyzed the structure and content of the competition period in mini-football. It was determined that the structure of the competition period consists of 4 competitive mesocycles. In each mesocycle includes various types of micro-cycles (competitive, cross-game and rehabilitation. Reflects the ratio of specific and non-specific (general preparations means training work. So in the competitive period for competitive mesocycles general preparations exercises ranged from 38.3 to 42.4%, special-preparation - from 29.9 to 32.6%, competitive - from 20.9 to 23.3%. The intensity of the training load in intergame microcycles less than competitive. This corresponds to the strategy of building the training process in the competitive period. During the competition period the ratio of the training load was: aerobic focus - 49.2%, mixed - 46.1%, anaerobic alactate - 2.4%, anaerobic glycolytic - 2.3%. Defines the scope and focus of the training load: longer the aerobic work, then - mixed, anaerobic- alactate and anaerobic-glycolytic. The comparative characteristics of the intensity of the training load in competitive and intergame microcycles.

  10. 3D Bioprinting of Carboxymethylated-Periodate Oxidized Nanocellulose Constructs for Wound Dressing Applications.

    Science.gov (United States)

    Rees, Adam; Powell, Lydia C; Chinga-Carrasco, Gary; Gethin, David T; Syverud, Kristin; Hill, Katja E; Thomas, David W

    2015-01-01

    Nanocellulose has a variety of advantages, which make the material most suitable for use in biomedical devices such as wound dressings. The material is strong, allows for production of transparent films, provides a moist wound healing environment, and can form elastic gels with bioresponsive characteristics. In this study, we explore the application of nanocellulose as a bioink for modifying film surfaces by a bioprinting process. Two different nanocelluloses were used, prepared with TEMPO mediated oxidation and a combination of carboxymethylation and periodate oxidation. The combination of carboxymethylation and periodate oxidation produced a homogeneous material with short nanofibrils, having widths material with good rheological properties for use as a bioink. The nanocellulose bioink was thus used for printing 3D porous structures, which is exemplified in this study. We also demonstrated that both nanocelluloses did not support bacterial growth, which is an interesting property of these novel materials.

  11. 3D Bioprinting of Carboxymethylated-Periodate Oxidized Nanocellulose Constructs for Wound Dressing Applications

    Directory of Open Access Journals (Sweden)

    Adam Rees

    2015-01-01

    Full Text Available Nanocellulose has a variety of advantages, which make the material most suitable for use in biomedical devices such as wound dressings. The material is strong, allows for production of transparent films, provides a moist wound healing environment, and can form elastic gels with bioresponsive characteristics. In this study, we explore the application of nanocellulose as a bioink for modifying film surfaces by a bioprinting process. Two different nanocelluloses were used, prepared with TEMPO mediated oxidation and a combination of carboxymethylation and periodate oxidation. The combination of carboxymethylation and periodate oxidation produced a homogeneous material with short nanofibrils, having widths <20 nm and lengths <200 nm. The small dimensions of the nanofibrils reduced the viscosity of the nanocellulose, thus yielding a material with good rheological properties for use as a bioink. The nanocellulose bioink was thus used for printing 3D porous structures, which is exemplified in this study. We also demonstrated that both nanocelluloses did not support bacterial growth, which is an interesting property of these novel materials.

  12. Development of a power-assisted lifting device for construction and periodic inspection

    International Nuclear Information System (INIS)

    Hayatsu, M.; Yamada, M.; Takasu, H.; Tagawa, Y.; Kajiwara, K.

    2001-01-01

    This study focuses on the control system design and control performance of a power-assisted lifting device. The device consists of several electric chain-blocks, each controlled by force sensors and a CPU. The mechanism is as follows: (1) Force sensors detect any chain tension changes (by human force), (2) The CPU calculates the required output, (3) Electric chain-blocks move the object in the intended direction. The feature of this device is that it does not require any information related to the suspension points of the electric chain-blocks. The controller was designed using the H method, which considers disturbances and aims to provide robust stability under the operation conditions of construction verified through experiments using a 700 kg steel dummy mass (control object) suspended by four electric chain-blocks. In the experiments, the controller, which was designed using the H method, was compared to the PI controller method, and the effectiveness of the H controller was proven. A control object could be moved, translated, and rotated by human force (of less than 10 kg). Positioning performance errors were suppressed to less than 0.5 mm, and operation time was reduced by about 50%. This device will improve working efficiency and rationalize lifting operations in nuclear power plants. (author)

  13. Development of a power-assisted lifting device for construction and periodic inspection

    Energy Technology Data Exchange (ETDEWEB)

    Hayatsu, M.; Yamada, M.; Takasu, H. [Hitachi Plant Engineering and Construction, Chiba-ken (Japan); Tagawa, Y. [Tokyo Univ. of Agriculture and Technology (Japan); Kajiwara, K. [National Research Institute for Earth Science and Disaster Prevention, Tokyo (Japan)

    2001-07-01

    This study focuses on the control system design and control performance of a power-assisted lifting device. The device consists of several electric chain-blocks, each controlled by force sensors and a CPU. The mechanism is as follows: (1) Force sensors detect any chain tension changes (by human force), (2) The CPU calculates the required output, (3) Electric chain-blocks move the object in the intended direction. The feature of this device is that it does not require any information related to the suspension points of the electric chain-blocks. The controller was designed using the H method, which considers disturbances and aims to provide robust stability under the operation conditions of construction verified through experiments using a 700 kg steel dummy mass (control object) suspended by four electric chain-blocks. In the experiments, the controller, which was designed using the H method, was compared to the PI controller method, and the effectiveness of the H controller was proven. A control object could be moved, translated, and rotated by human force (of less than 10 kg). Positioning performance errors were suppressed to less than 0.5 mm, and operation time was reduced by about 50%. This device will improve working efficiency and rationalize lifting operations in nuclear power plants. (author)

  14. Hypofractionated Breast Radiation: Shorter Scheme, Lower Toxicity.

    Science.gov (United States)

    Linares, Isabel; Tovar, María Isabel; Zurita, Mercedes; Guerrero, Rosario; Expósito, Manuela; Del Moral, Rosario

    2016-08-01

    We analyzed the toxicity and cosmetic outcomes for patients who had undergone 3-dimensional conformal radiotherapy with a hypofractionated schedule and identified the risk factors associated with such a schedule. A total of 143 patients were treated for breast cancer (stage 0-III) with a hypofractionated radiation schedule after breast-conserving surgery from 2006 to 2011. Most patients received 42.4 Gy in 16 daily fractions, 2.65 Gy per fraction to the whole breast plus an additional simultaneous integrated or sequential boost to the tumor bed. The median follow-up period was 36 months. Mild acute skin toxicity was observed in 62%; 7% of the patients developed moderate skin toxicity, but no grade 4 toxicity was observed. The prevalence of fibrosis within the boost area was 5%, but no grade ≥ 2 was observed. The prevalence of fibrosis of any grade was greater in the nonboost (23%) than in the boost area. Of all the patients, 91% had good or excellent cosmetic outcomes. From the multivariate analysis, the incidence of epithelitis correlated with the patient's treated volume (P = .044). The incidence of acute toxicity correlated with the boost type to the tumor bed and the total treatment dose (P = .012 and P = .002, respectively). Also, a poor to fair cosmetic outcome was significantly associated statistically with the surgery type (P = .05), boost type (P = .004), and total dose (P = .001). Delivering whole-breast irradiation with a hypofractionated schedule of 42.4 Gy plus a simultaneous integrated boost to the tumor bed appears to be a safe and effective technique, with good cosmetic results and lower toxicity. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Construction and properties of a topological index for periodically driven time-reversal invariant 2D crystals

    Directory of Open Access Journals (Sweden)

    D. Carpentier

    2015-07-01

    Full Text Available We present mathematical details of the construction of a topological invariant for periodically driven two-dimensional lattice systems with time-reversal symmetry and quasienergy gaps, which was proposed recently by some of us. The invariant is represented by a gap-dependent Z2-valued index that is simply related to the Kane–Mele invariants of quasienergy bands but contains an extra information. As a byproduct, we prove new expressions for the two-dimensional Kane–Mele invariant relating the latter to Wess–Zumino amplitudes and the boundary gauge anomaly.

  16. Penalty model for delay of bidding section construction period in South-to-North Water Diversion Eastern Route Project from perspective of programs

    Directory of Open Access Journals (Sweden)

    Jing-chun Feng

    2012-09-01

    Full Text Available According to the multi-project and program management theory, this paper analyzes the program generation principle and establishes a program based on progress goals. On the basis of the present situation of calculation of penalty for delay of the bidding section construction period with the critical path method, we studied the effects of contractor-induced delay of the bidding section construction period in detail, including the effects on the construction period of the bidding section itself, the earliest start times of the next bidding section and other subsequent bidding sections, and the construction period of the program, and then constructed a penalty model for delay of the bidding section construction period from the perspective of programs. Using the penalty model, we conducted a practical analysis of penalty for delay of the construction period of the Baoying station program in the South-to-North Water Diversion Project. The model can help determine the amount of penalty for delay of the construction period in bidding sections scientifically and reasonably.

  17. The Napoleon Complex: When Shorter Men Take More.

    Science.gov (United States)

    Knapen, Jill E P; Blaker, Nancy M; Van Vugt, Mark

    2018-05-01

    Inspired by an evolutionary psychological perspective on the Napoleon complex, we hypothesized that shorter males are more likely to show indirect aggression in resource competitions with taller males. Three studies provide support for our interpretation of the Napoleon complex. Our pilot study shows that men (but not women) keep more resources for themselves when they feel small. When paired with a taller male opponent (Study 1), shorter men keep more resources to themselves in a game in which they have all the power (dictator game) versus a game in which the opponent also has some power (ultimatum game). Furthermore, shorter men are not more likely to show direct, physical aggression toward a taller opponent (Study 2). As predicted by the Napoleon complex, we conclude that (relatively) shorter men show greater behavioral flexibility in securing resources when presented with cues that they are physically less competitive. Theoretical and practical implications are discussed.

  18. [Impact of maternal HIV status on family constructions and the infant's relational environment during the perinatal period].

    Science.gov (United States)

    Trocmé, N; Courcoux, M-F; Tabone, M-D; Leverger, G; Dollfus, C

    2013-01-01

    To assess whether maternal HIV-positive status negatively affects family construction and the child's psychological environment. Could this be responsible for behavioral problems observed in children infected with or affected by HIV? Interviews were conducted with 60 HIV+ mothers and their infants during the perinatal period, within 3 months of delivery, collected at the time of a pediatric outpatient visit within a PMTCT program. Half of the 60 mothers did not live with the infant's father, 56% of multiparous mothers were separated from their previous children. Sixty-five percent of the fathers were informed of the mother's HIV-positive status, although 90% of fathers who lived with the mothers were informed. During pregnancy, 80% of mothers reported psychological stress; after delivery, 72% of mothers suffered from not being allowed to breastfeed their infants, 43.5% expressed a fear of transmitting the infection to the child, and 40% avoided contacts with the infant. The impact of the mother's psychological stress and anxiety related to the risk of HIV transmission through breastfeeding and casual contacts were already noticeable in the first mother-child interrelations. Although the risk of MTC transmission in now very small, psychological troubles related to maternal HIV status may negatively affect the children's well-being and behavior, psychological support should be provided for mothers and children as part of comprehensive services. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  19. Experimental study on rapid embankment construction methods

    International Nuclear Information System (INIS)

    Hirano, Hideaki; Egawa, Kikuji; Hyodo, Kazuya; Kannoto, Yasuo; Sekimoto, Tsuyoshi; Kobayashi, Kokichi.

    1982-01-01

    In the construction of a thermal or nuclear power plant in a coastal area, shorter embankment construction period has come to be called for recently. This tendency is remarkable where construction period is limited due to meteorological or sea conditions. To meet this requirement, the authors have been conducting basic experimental studies on two methods for the rapid execution of embankment construction, that is, Steel Plate Cellular Bulkhead Embedding Method and Ship Hull Caisson Method. This paper presents an outline of the results of the experimental study on these two methods. (author)

  20. The “green wave” mode production on the two-lane highways during the construction works time period

    Directory of Open Access Journals (Sweden)

    А. Berezhnoy

    2007-12-01

    Full Text Available In the paper, the problem of a bi-directional “green wave” mode production is considered for the vehicle flows motion on two-lane highways during the conducting of construction works. The solution of the given task allows to develop practical recommendations for the sphere of the construction works management on two-lane roads and country highways, and also to raise traffic control efficiency in the pointed conditions. The comparative analysis of possible traffic regulation modes for the set scheme of road construction works sites and the estimation of their effi ciency is performed, the test of a hypothesis regarding the possibility of a bi-directional “green wave” mode realization is carried out, and calculation of traffic lights signal control phases time is performed.

  1. One long chain among shorter chains : the Flory approach revisited

    OpenAIRE

    Raphaël , E.; Fredrickson , G.; Pincus , P.

    1992-01-01

    We consider the mean square end-to-end distance of a long chain immersed in a monodisperse, concentrated solution of shorter, chemically identical chains. In contrast with the earlier work of Flory, no simplifying assumption on the wave vector dependence of the effective potential between segments is made. In order to obtain a closed form expression for the dimension of the long chain, we first derive a general expression for the mean square end-to-end distance of a flexible chain with arbitr...

  2. Analytical and numerical construction of vertical periodic orbits about triangular libration points based on polynomial expansion relations among directions

    Science.gov (United States)

    Qian, Ying-Jing; Yang, Xiao-Dong; Zhai, Guan-Qiao; Zhang, Wei

    2017-08-01

    Innovated by the nonlinear modes concept in the vibrational dynamics, the vertical periodic orbits around the triangular libration points are revisited for the Circular Restricted Three-body Problem. The ζ -component motion is treated as the dominant motion and the ξ and η -component motions are treated as the slave motions. The slave motions are in nature related to the dominant motion through the approximate nonlinear polynomial expansions with respect to the ζ -position and ζ -velocity during the one of the periodic orbital motions. By employing the relations among the three directions, the three-dimensional system can be transferred into one-dimensional problem. Then the approximate three-dimensional vertical periodic solution can be analytically obtained by solving the dominant motion only on ζ -direction. To demonstrate the effectiveness of the proposed method, an accuracy study was carried out to validate the polynomial expansion (PE) method. As one of the applications, the invariant nonlinear relations in polynomial expansion form are used as constraints to obtain numerical solutions by differential correction. The nonlinear relations among the directions provide an alternative point of view to explore the overall dynamics of periodic orbits around libration points with general rules.

  3. Micropole Undulators In Synchrotron Radiation Technology: Design And Construction Of A Submillimeter Period Prototype With A 3 Kilogauss Peak Field At SSRL

    Science.gov (United States)

    Tatchyn, Roman; Csonka, Paul

    1986-01-01

    The availability of undulators with submillimeter periods will profoundly affect the future development of soft x-ray sources and their attendant instrumentation. Outputs comparable to those of present-day conventional undulators, obtainable with much lower energy storage rings, is only one promising aspect of such devices. This paper critically examines some of the future prospects of such devices and describes the design and practical construction of a 1" long prototype consisting of 35 periods. A proposed experiment to test this device on a linac is described.

  4. Micropole undulators in synchrotron radiation technology: Design and construction of a submillimeter period prototype with a 3 kilogauss peak field at SSRL

    International Nuclear Information System (INIS)

    Tatchyn, R.; Csonka, P.

    1987-01-01

    The availability of undulators with submillimeter periods profoundly affects the future development of soft x-ray sources and their attendant instrumentation. Outputs comparable to those of present-day conventional undulators, obtainable with much lower energy storage rings, is only one promising aspect of such devices. This paper critically examines some of the future prospects of such devices and describes the design and practical construction of a 1'' long prototype consisting of 35 periods. A proposed experiment to test this device on a linac is described

  5. Study of building typology of school constructed during the Dutch Colonial Period in Indonesia. Case study of Hoogere Burgerschool (HBS) in Bandung

    Science.gov (United States)

    Sarwo Wibowo, Arif

    2018-03-01

    Bandung is one of the most important colonial cities in Indonesia. In the early 20th century the capital city of Dutch East-Indies Government planned to move in Bandung. Critical infrastructures were intensively built during that period, such as streets and railways, houses, governmental buildings, train stations, hospitals and educational facilities. Besides the famous campus of Technische Hoogeschool te Bandoeng (ITB), still in the same period, several schools were also constructed. One of the most important schools was Hoogere Burgerschool in Bandung (HBS Bandung), now SMUN 3 and 5, Bandung designed by Charles Prosper Wolff Schoemaker and constructed in 1915. HBS Bandung was the fourth HBS constructed by Dutch East Indies Government, therefore became important and put itself as a reference for the later school buildings in Bandung. This study is analyzing how the architects’ frame of mind in producing this design works. Survey and direct data collecting were used to take the exact embodiment of building design. Usage and functional analysis were also used to match space and other standard used in a school building at that time. This study will give an understanding of building typology of school during the Dutch Colonial Period in Indonesia.

  6. Programme for construction and reconstruction of electro energetic objects in the Republic of Macedonia in the period 1996-2005

    International Nuclear Information System (INIS)

    1996-01-01

    The programme is prepared by Macedonian Ministry of Economy, as well as Ministry of Development, Ministry of Finance, Chamber of Commerce of Macedonia and Electric Power Co. of Macedonia. The aim of programme is to perceive electric power needs in the period 1996-2005 , to propose electro energetic objects that have to be built in order to satisfy electric power needs, as well as to present both necessary finances and possible sources for finances providing

  7. Do shorter wavelengths improve contrast in optical mammography?

    International Nuclear Information System (INIS)

    Taroni, P; Pifferi, A; Torricelli, A; Spinelli, L; Danesini, G M; Cubeddu, R

    2004-01-01

    The detection of tumours with time-resolved transmittance imaging relies essentially on blood absorption. Previous theoretical and phantom studies have shown that both contrast and spatial resolution of optical images are affected by the optical properties of the background medium, and high absorption and scattering are generally beneficial. Based on these observations, wavelengths shorter than presently used (680-780 nm) could be profitable for optical mammography. A study was thus performed analysing time-resolved transmittance images at 637, 656, 683 and 785 nm obtained from 26 patients bearing 16 tumours and 15 cysts. The optical contrast proved to increase upon decreasing wavelengths for the detection of cancers in late-gated intensity images, with higher gain in contrast for lesions of smaller size (<1.5 cm diameter). For cysts either a progressive increase or decrease in contrast with wavelength was observed in scattering images

  8. The risk of shorter fasting time for pediatric deep sedation.

    Science.gov (United States)

    Clark, Mathew; Birisci, Esma; Anderson, Jordan E; Anliker, Christina M; Bryant, Micheal A; Downs, Craig; Dalabih, Abdallah

    2016-01-01

    Current guidelines adopted by the American Academy of Pediatrics calls for prolonged fasting times before performing pediatric procedural sedation and analgesia (PSA). PSA is increasingly provided to children outside of the operating theater by sedation trained pediatric providers and does not require airway manipulation. We investigated the safety of a shorter fasting time compared to a longer and guideline compliant fasting time. We tried to identify the association between fasting time and sedation-related complications. This is a prospective observational study that included children 2 months to 18 years of age and had an American Society of Anesthesiologists physical status classification of I or II, who underwent deep sedation for elective procedures, performed by pediatric critical care providers. Procedures included radiologic imaging studies, electroencephalograms, auditory brainstem response, echocardiograms, Botox injections, and other minor surgical procedures. Subjects were divided into two groups depending on the length of their fasting time (4-6 h and >6 h). Complication rates were calculated and compared between the three groups. In the studied group of 2487 subjects, 1007 (40.5%) had fasting time of 4-6 h and the remaining 1480 (59.5%) subjects had fasted for >6 h. There were no statistically significant differences in any of the studied complications between the two groups. This study found no difference in complication rate in regard to the fasting time among our subjects cohort, which included only healthy children receiving elective procedures performed by sedation trained pediatric critical care providers. This suggests that using shorter fasting time may be safe for procedures performed outside of the operating theater that does not involve high-risk patients or airway manipulation.

  9. Construction of a surface air temperature series for Qingdao in China for the period 1899 to 2014

    Science.gov (United States)

    Li, Yan; Tinz, Birger; von Storch, Hans; Wang, Qingyuan; Zhou, Qingliang; Zhu, Yani

    2018-03-01

    We present a homogenized surface air temperature (SAT) time series at 2 m height for the city of Qingdao in China from 1899 to 2014. This series is derived from three data sources: newly digitized and homogenized observations of the German National Meteorological Service from 1899 to 1913, homogenized observation data of the China Meteorological Administration (CMA) from 1961 to 2014 and a gridded dataset of Willmott and Matsuura (2012) in Delaware to fill the gap from 1914 to 1960. Based on this new series, long-term trends are described. The SAT in Qingdao has a significant warming trend of 0.11 ± 0.03 °C decade-1 during 1899-2014. The coldest period occurred during 1909-1918 and the warmest period occurred during 1999-2008. For the seasonal mean SAT, the most significant warming can be found in spring, followed by winter. The homogenized time series of Qingdao is provided and archived by the Deutscher Wetterdienst (DWD) web page under overseas stations of the Deutsche Seewarte (http://www.dwd.de/EN/ourservices/overseas_stations/ueberseedoku/doi_qingdao.html) in ASCII format. Users can also freely obtain a short description of the data at https://doi.org/https://dx.doi.org/10.5676/DWD/Qing_v1" target="_blank">https://doi.org/https://dx.doi.org/10.5676/DWD/Qing_v1. And the data can be downloaded at http://dwd.de/EN/ourservices/overseas_stations/ueberseedoku/data_qingdao.txt.

  10. Socio-Economic Problems of the Russian Construction of Art Nouveau Period (on the Example of A.I. Lishnevsky’s Activity

    Directory of Open Access Journals (Sweden)

    Aleksandr I. Chepel

    2017-09-01

    Full Text Available The author studies the specifics of Russian architect’s work on the example of the activity of prominent architect of Art Nouveau period A.L. Lishnevsky (1868–1942. The special attention is paid to the architect’s relations with the authorities, contractors and workers, as well as with customers and colleagues. The author shows the opinion of citizens about the activities of an architect as a builder and businessman, reveals the main socio-economic problems which the architect faced from the moment of inception and approval of the project prior to its actual implementation. The author attempts to trace the mechanism of professional networking in the architecture environment of that time, and to reveal the peculiarities of private architectural bureaus (“offices”. The attention is paid to the assessment by the architect of their own professional activity. A.L. Lishnevsky’s activity is a good example of architect’s work in the construction business. A native of the city of Kherson, he received the metropolitan education at the Art Academy, then for over six years (1895–1901 he worked as a municipal architect in Elisavetgrad (Kirovograd, since 2016 – Kropivnytsky during the period of rapid economic and cultural growth of the town. After 1901 and up to 1917 he was actively engaged in municipal and private construction in the capital of the Russian Empire, Saint Petersburg. The relevance of the topic is determined by the fact that the Art Nouveau period architect worked in capitalism construction market, and was forced to deal with issues similar to those that the architects of our time solve. The study is based on materials from Russian archives and periodicals of late 19th – early 20th century.

  11. The role of romantic attraction and conflict resolution in predicting shorter and longer relationship maintenance among adolescents.

    Science.gov (United States)

    Appel, Israel; Shulman, Shmuel

    2015-04-01

    This study examined the role of romantic attraction and conflict resolution patterns in shorter and longer relationship maintenance among adolescent couples. Data were used from 55 couples aged 15-18 years. Partners completed the Romantic Attraction scale and were observed negotiating a disagreement. Three and 6 months later, they were asked to report whether they were still together. Findings indicated that partners' romantic attraction and the tendency to minimize disagreements during interaction predicted shorter relationship maintenance. In contrast, longer relationship maintenance was predicted by partners' capability to resolve conflicts constructively in a positive atmosphere. Findings are embedded and discussed within Fisher's (2004) evolutionary theory of love.

  12. Abnormal arrangement of a collagen/apatite extracellular matrix orthogonal to osteoblast alignment is constructed by a nanoscale periodic surface structure.

    Science.gov (United States)

    Matsugaki, Aira; Aramoto, Gento; Ninomiya, Takafumi; Sawada, Hiroshi; Hata, Satoshi; Nakano, Takayoshi

    2015-01-01

    Morphological and directional alteration of cells is essential for structurally appropriate construction of tissues and organs. In particular, osteoblast alignment is crucial for the realization of anisotropic bone tissue microstructure. In this article, the orientation of a collagen/apatite extracellular matrix (ECM) was established by controlling osteoblast alignment using a surface geometry with nanometer-sized periodicity induced by laser ablation. Laser irradiation induced self-organized periodic structures (laser-induced periodic surface structures; LIPSS) with a spatial period equal to the wavelength of the incident laser on the surface of biomedical alloys of Ti-6Al-4V and Co-Cr-Mo. Osteoblast orientation was successfully induced parallel to the grating structure. Notably, both the fibrous orientation of the secreted collagen matrix and the c-axis of the produced apatite crystals were orientated orthogonal to the cell direction. To the best of our knowledge, this is the first report demonstrating that bone tissue anisotropy is controllable, including the characteristic organization of a collagen/apatite composite orthogonal to the osteoblast orientation, by controlling the cell alignment using periodic surface geometry. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Towards shorter wavelength x-ray lasers using a high power, short pulse pump laser

    International Nuclear Information System (INIS)

    Tighe, W.; Krushelnick, K.; Valeo, E.; Suckewer, S.

    1991-05-01

    A near-terawatt, KrF* laser system, focussable to power densities >10 18 W/cm 2 has been constructed for use as a pump laser in various schemes aimed at the development of x-ray lasing below 5nm. The laser system along with output characteristics such as the pulse duration, the focal spot size, and the percentage of amplified spontaneous emission (ASE) emitted along with the laser pulse will be presented. Schemes intended to lead to shorter wavelength x-ray emission will be described. The resultant requirements on the pump laser characteristics and the target design will be outlined. Results from recent solid target experiments and two-laser experiments, showing the interaction of a high-power, short pulse laser with a preformed plasma, will be presented. 13 refs., 5 figs

  14. Shorter Decentralized Attribute-Based Encryption via Extended Dual System Groups

    Directory of Open Access Journals (Sweden)

    Jie Zhang

    2017-01-01

    Full Text Available Decentralized attribute-based encryption (ABE is a special form of multiauthority ABE systems, in which no central authority and global coordination are required other than creating the common reference parameters. In this paper, we propose a new decentralized ABE in prime-order groups by using extended dual system groups. We formulate some assumptions used to prove the security of our scheme. Our proposed scheme is fully secure under the standard k-Lin assumption in random oracle model and can support any monotone access structures. Compared with existing fully secure decentralized ABE systems, our construction has shorter ciphertexts and secret keys. Moreover, fast decryption is achieved in our system, in which ciphertexts can be decrypted with a constant number of pairings.

  15. Codes in the codons: construction of a codon/amino acid periodic table and a study of the nature of specific nucleic acid-protein interactions.

    Science.gov (United States)

    Benyo, B; Biro, J C; Benyo, Z

    2004-01-01

    The theory of "codon-amino acid coevolution" was first proposed by Woese in 1967. It suggests that there is a stereochemical matching - that is, affinity - between amino acids and certain of the base triplet sequences that code for those amino acids. We have constructed a common periodic table of codons and amino acids, where the nucleic acid table showed perfect axial symmetry for codons and the corresponding amino acid table also displayed periodicity regarding the biochemical properties (charge and hydrophobicity) of the 20 amino acids and the position of the stop signals. The table indicates that the middle (2/sup nd/) amino acid in the codon has a prominent role in determining some of the structural features of the amino acids. The possibility that physical contact between codons and amino acids might exist was tested on restriction enzymes. Many recognition site-like sequences were found in the coding sequences of these enzymes and as many as 73 examples of codon-amino acid co-location were observed in the 7 known 3D structures (December 2003) of endonuclease-nucleic acid complexes. These results indicate that the smallest possible units of specific nucleic acid-protein interaction are indeed the stereochemically compatible codons and amino acids.

  16. A shorter and more specific oral sensitization-based experimental model of food allergy in mice.

    Science.gov (United States)

    Bailón, Elvira; Cueto-Sola, Margarita; Utrilla, Pilar; Rodríguez-Ruiz, Judith; Garrido-Mesa, Natividad; Zarzuelo, Antonio; Xaus, Jordi; Gálvez, Julio; Comalada, Mònica

    2012-07-31

    Cow's milk protein allergy (CMPA) is one of the most prevalent human food-borne allergies, particularly in children. Experimental animal models have become critical tools with which to perform research on new therapeutic approaches and on the molecular mechanisms involved. However, oral food allergen sensitization in mice requires several weeks and is usually associated with unspecific immune responses. To overcome these inconveniences, we have developed a new food allergy model that takes only two weeks while retaining the main characters of allergic response to food antigens. The new model is characterized by oral sensitization of weaned Balb/c mice with 5 doses of purified cow's milk protein (CMP) plus cholera toxin (CT) for only two weeks and posterior challenge with an intraperitoneal administration of the allergen at the end of the sensitization period. In parallel, we studied a conventional protocol that lasts for seven weeks, and also the non-specific effects exerted by CT in both protocols. The shorter protocol achieves a similar clinical score as the original food allergy model without macroscopically affecting gut morphology or physiology. Moreover, the shorter protocol caused an increased IL-4 production and a more selective antigen-specific IgG1 response. Finally, the extended CT administration during the sensitization period of the conventional protocol is responsible for the exacerbated immune response observed in that model. Therefore, the new model presented here allows a reduction not only in experimental time but also in the number of animals required per experiment while maintaining the features of conventional allergy models. We propose that the new protocol reported will contribute to advancing allergy research. Copyright © 2012 Elsevier B.V. All rights reserved.

  17. Toshiba's developments on construction techniques of nuclear power plants

    International Nuclear Information System (INIS)

    Hayashi, Y.; Itoh, N.

    1987-01-01

    Reliable and economic energy supplies are fundamental requirements of energy policies in Japan. To accomplish these needs, nuclear power plants are being increased in Japan. In recent years, construction cost increases and schedule extensions have affected the capital cost of nuclear energy, compared with fossil power plants, due to lower costs of oil and coal. On the other hand, several severe regulations have been applied to nuclear power plant designs. High-quality and cooperative engineering and harmonized design of equipment and parts are strongly required. Therefore, reduced construction costs and scheduling, as well as higher quality and reliability, are the most important items for nuclear industry. Toshiba has developed new construction techniques, as well as design and engineering tools for control and management, that demonstrate the positive results achieved in the shorter construction period of 1100-MW(electric) nuclear power plants. The normal construction period so far is 64 months, whereas the current construction period is 52 months. (New construction techniques are partially applied). In future years, the construction period will be lowered to 48 months. (New construction techniques are fully applied). A construction period is defined as time from the start of rock inspection to the start of commercial operation

  18. The layout of urban construction in Bolghar in the late Golden Horde period (preliminary results of studies on materials of excavations Southwest of the Cathedral Mosque

    Directory of Open Access Journals (Sweden)

    Badeev Denis Yu.

    2014-06-01

    Full Text Available The results of the archaeological studies on a monumental building, identified in the central part of the Bolghar fortified settlement site, 150 meters southwest of the Cathedral Mosque, during the 1989-1993, 2000 and 2011-2013 works are presented. Adobe brick masonry and remains of wooden flooring have been recorded. Findings in the form of numerous a large number of commercial stock-in-trade items and coins allow interpreting this building as the city market. The authors of the excavations of the building date it back to the 50-70s of the 14th century. The structural elements of the construction and its internal layout suggest the existence of the city market at the intersection of two streets. The presence of street system in this part of the city is also indicated by the remains of two brickworks of mud bricks, which had served as a street fence (duval and referred to layers of the 30-40s of the 14th century. In the mid-14th century, the building of the city market had been being erected in place of the street fence and the adjoining estates. Thus, the development dynamics of Bolghar urban planning in the Late Golden Horde period on the site southwest of the Cathedral Mosque could be traced.

  19. FORECASTING ENERGY CONSUMPTION IN SHORT-TERM AND LONG-TERM PERIOD BY USING ARIMAX MODEL IN THE CONSTRUCTION AND MATERIALS SECTOR IN THAILAND

    Directory of Open Access Journals (Sweden)

    Pruethsan Sutthichaimethee

    2017-07-01

    Full Text Available This study aims to analyze the forecasting of energy consumption in the Construction and Materials sectors. The scope of the study covers the forecasting periods of energy consumption for the next 10 years, 2017-2026, 20 years, 2017-2036, and 30 years, 2017-2046, by using ARIMAX Model. The prediction results show that these models are effective in the forecast measured by RMSE, MAE, and MAPE. The results show that from the first model (2,1,1, which predicted the duration of 10 years, 2017-2026, indicates that Thailand has increased an energy consumption rate with the average of 18.09%, while the second model (2,1,2 with the prediction of 20 years, 2017-2036, Thailand arises its energy consumption up to 37.32%. In addition, the third model (2,1,3 predicted the duration of 30 years from 2017 to 2046, and it has found that Thailand increases its energy consumption up to 49.72%.

  20. Smoking Topography among Korean Smokers: Intensive Smoking Behavior with Larger Puff Volume and Shorter Interpuff Interval.

    Science.gov (United States)

    Kim, Sungroul; Yu, Sol

    2018-05-18

    The difference of smoker's topography has been found to be a function many factors, including sex, personality, nicotine yield, cigarette type (i.e., flavored versus non-flavored) and ethnicity. We evaluated the puffing behaviors of Korean smokers and its association with smoking-related biomarker levels. A sample of 300 participants was randomly recruited from metropolitan areas in South Korea. Topography measures during a 24-hour period were obtained using a CReSS pocket device. Korean male smokers smoked two puffs less per cigarette compared to female smokers (15.0 (13.0⁻19.0) vs. 17.5 (15.0⁻21.0) as the median (Interquartile range)), but had a significantly larger puff volume (62.7 (52.7⁻75.5) mL vs. 53.5 (42.0⁻64.2) mL); p = 0.012). The interpuff interval was similar between men and women (8.9 (6.5⁻11.2) s vs. 8.3 (6.2⁻11.0) s; p = 0.122) but much shorter than other study results. A dose-response association ( p = 0.0011) was observed between daily total puff volumes and urinary cotinine concentrations, after controlling for sex, age, household income level and nicotine addiction level. An understanding of the difference of topography measures, particularly the larger puff volume and shorter interpuff interval of Korean smokers, may help to overcome a potential underestimation of internal doses of hazardous byproducts of smoking.

  1. Improvements in the construction of nuclear power plant

    International Nuclear Information System (INIS)

    1990-01-01

    This paper outlines activities to minimize the amount of work at a construction site by employing installation method with large size blocks and shop-assembled units, improvement in facilities such as mechanization of welding and huge roof cover which enables work in all weather conditions, and administration systems using computer for the work activity control as well as quality and progress control for construction work. These improvements are only achieved when supported by related system improvements at the design and fabrication stage, and these improvements contributed a great deal to the quality assurance and the shorter construction period. (author)

  2. Shorter Fallow Cycles Affect the Availability of Noncrop Plant Resources in a Shifting Cultivation System

    Directory of Open Access Journals (Sweden)

    Sarah Paule. Dalle

    2006-12-01

    Full Text Available Shifting cultivation systems, one of the most widely distributed forms of agriculture in the tropics, provide not only crops of cultural significance, but also medicinal, edible, ritual, fuel, and forage resources, which contribute to the livelihoods, health, and cultural identity of local people. In many regions across the globe, shifting cultivation systems are undergoing important changes, one of the most pervasive being a shortening of the fallow cycle. Although there has been much attention drawn to declines in crop yields in conjunction with reductions in fallow times, little if any research has focused on the dynamics of noncrop plant resources. In this paper, we use a data set of 26 fields of the same age, i.e., ~1.5 yr, but differing in the length and frequency of past fallow cycles, to examine the impact of shorter fallow periods on the availability of noncrop plant resources. The resources examined are collected in shifting cultivation fields by the Yucatec Maya in Quintana Roo, Mexico. These included firewood, which is cut from remnant trees and stumps spared at the time of felling, and 17 forage species that form part of the weed vegetation. Firewood showed an overall decrease in basal area with shorter fallow cycles, which was mostly related to the smaller diameter of the spared stumps and trees in short-fallow milpas. In contrast, forage species showed a mixed response. Species increasing in abundance in short-fallow milpas tended to be short-lived herbs and shrubs often with weedy habits, whereas those declining in abundance were predominantly pioneer trees and animal-dispersed species. Coppicing tree species showed a neutral response to fallow intensity. Within the cultural and ecological context of our study area, we expect that declines in firewood availability will be most significant for livelihoods because of the high reliance on firewood for local fuel needs and the fact that the main alternative source of firewood, forest

  3. Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants

    Science.gov (United States)

    Fisher, B.G.; Thankamony, A.; Hughes, I.A.; Ong, K.K.; Dunger, D.B.; Acerini, C.L.

    2016-01-01

    STUDY QUESTION What is the relationship between maternal paracetamol intake during the masculinisation programming window (MPW, 8–14 weeks of gestation) and male infant anogenital distance (AGD), a biomarker for androgen action during the MPW? SUMMARY ANSWER Intrauterine paracetamol exposure during 8–14 weeks of gestation is associated with shorter AGD from birth to 24 months of age. WHAT IS ALREADY KNOWN The increasing prevalence of male reproductive disorders may reflect environmental influences on foetal testicular development during the MPW. Animal and human xenograft studies have demonstrated that paracetamol reduces foetal testicular testosterone production, consistent with reported epidemiological associations between prenatal paracetamol exposure and cryptorchidism. STUDY DESIGN, SIZE, DURATION Prospective cohort study (Cambridge Baby Growth Study), with recruitment of pregnant women at ~12 post-menstrual weeks of gestation from a single UK maternity unit between 2001 and 2009, and 24 months of infant follow-up. Of 2229 recruited women, 1640 continued with the infancy study after delivery, of whom 676 delivered male infants and completed a medicine consumption questionnaire. PARTICIPANTS/MATERIALS, SETTING, METHOD Mothers self-reported medicine consumption during pregnancy by a questionnaire administered during the perinatal period. Infant AGD (measured from 2006 onwards), penile length and testicular descent were assessed at 0, 3, 12, 18 and 24 months of age, and age-specific Z scores were calculated. Associations between paracetamol intake during three gestational periods (14 weeks) and these outcomes were tested by linear mixed models. Two hundred and twenty-five (33%) of six hundred and eighty-one male infants were exposed to paracetamol during pregnancy, of whom sixty-eight were reported to be exposed during 8–14 weeks. AGD measurements were available for 434 male infants. MAIN RESULTS AND THE ROLE OF CHANCE Paracetamol exposure during 8–14

  4. SHORTER MENSTRUAL CYCLES ASSOCIATED WITH CHLORINATION BY-PRODUCTS IN DRINKING WATER

    Science.gov (United States)

    Shorter Menstrual Cycles Associated with Chlorination by-Products in Drinking Water. Gayle Windham, Kirsten Waller, Meredith Anderson, Laura Fenster, Pauline Mendola, Shanna Swan. California Department of Health Services.In previous studies of tap water consumption we...

  5. Hypermetabolism in ALS is associated with greater functional decline and shorter survival.

    Science.gov (United States)

    Steyn, Frederik J; Ioannides, Zara A; van Eijk, Ruben P A; Heggie, Susan; Thorpe, Kathryn A; Ceslis, Amelia; Heshmat, Saman; Henders, Anjali K; Wray, Naomi R; van den Berg, Leonard H; Henderson, Robert D; McCombe, Pamela A; Ngo, Shyuan T

    2018-04-29

    To determine the prevalence of hypermetabolism, relative to body composition, in amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and survival. Fifty-eight patients with clinically definite or probable ALS as defined by El Escorial criteria, and 58 age and sex-matched control participants underwent assessment of energy expenditure. Our primary outcome was the prevalence of hypermetabolism in cases and controls. Longitudinal changes in clinical parameters between hypermetabolic and normometabolic patients with ALS were determined for up to 12 months following metabolic assessment. Survival was monitored over a 30-month period following metabolic assessment. Hypermetabolism was more prevalent in patients with ALS than controls (41% vs 12%, adjusted OR=5.4; pALS. Mean lower motor neuron score (SD) was greater in hypermetabolic patients when compared with normometabolic patients (4 (0.3) vs 3 (0.7); p=0.04). In the 12 months following metabolic assessment, there was a greater change in Revised ALS Functional Rating Scale score in hypermetabolic patients when compared with normometabolic patients (-0.68 points/month vs -0.39 points/month; p=0.01). Hypermetabolism was inversely associated with survival. Overall, hypermetabolism increased the risk of death during follow-up to 220% (HR 3.2, 95% CI 1.1 to 9.4, p=0.03). Hypermetabolic patients with ALS have a greater level of lower motor neuron involvement, faster rate of functional decline and shorter survival. The metabolic index could be important for informing prognosis in ALS. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  6. Activities of the TUV experts during the period of construction and commissioning of a nuclear power plant ordered by the licensing authorities of the FRG

    International Nuclear Information System (INIS)

    Dommke, J.; Fendler, H.

    1977-01-01

    The inspection organisations in the Federal Republic of Germany (Technische Uberwachungs-Vereine) are independent systems grouped on a regional basis. The competent licensing authorities of the various Lander consult them concerning assessments for site selection and the design, construction, commissioning and operation of nuclear power plants. Furthermore the TUV experts inspect the manufacture of components in the suppliers' facilities and on site. (NEA) [fr

  7. Urdu translation and validation of shorter version of Positive Affect and Negative Affect Schedule (PANAS) on Pakistani bank employees.

    Science.gov (United States)

    Akhter, Noreen

    2017-10-01

    To translate, adapt and validate shorter version of positive affect and negative affect scale on Pakistani corporate employees. This cross-sectional study was conducted in the twin cities of Islamabad and Rawalpindi from October 2014 to December 2015. The study was completed into two independent parts. In part one, the scale was translated by forward translation. Then it was pilot-tested and administered on customer services employees from commercial banks and the telecommunication sector. Data of the pilot study was analysed by using exploratory factor analysis to extract the initial factor of positive affect and negative affect scale. Part two comprised the main study. Commercial bank employees were included in the sample using convenient sampling technique. Data of the main study was analysed using confirmatory factor analysis in order to establish construct validity of positive affect and negative affect scale. There were145 participants in the first part of the study and 495 in the second. Results of confirmatory factor analysis confirmed the two-factor structure of positive affect and negative affect scale suggesting that the scale has two distinct domains, i.e. positive affect and negative affect. The shorter version of positive affect and negative affect scale was found to be a valid and reliable measure.

  8. Dam construction in salt rock

    International Nuclear Information System (INIS)

    Stockmann, N.; Beinlich, A.; Flach, D.; Jockwer, N.; Klarr, K.; Krogmann, P.; Miehe, R.; Schmidt, M.W.; Schwaegermann, H.F.; Walter, F.; Yaramanci, U.

    1991-11-01

    Barriers are a major component of the satefy concept for the Gorleben repository. The construction and performance of dams are currently tested within the framework of a project carried out in the Asse salt mine. A measuring programme has been established to give evidence of the sealing capacities of a barrier consisting of an abatement, long-term sealing material, and a hydraulic sealing system. Tests are to be made to verify the barrier's performance for shorter of long time periods (up to about 500 years). The tests are assisted by computed models established for the project. The long-term safety aspects to be studied include such conditions as permeability changes due to mechanical impacts, circulation conditions at the roadside, and the serviceable life and efficiency of the sealing components. (DG) [de

  9. Shorter height is related to lower cardiovascular disease risk – A narrative review

    Directory of Open Access Journals (Sweden)

    Thomas T. Samaras

    2013-01-01

    Full Text Available Numerous Western studies have shown a negative correlation between height and cardiovascular disease. However, these correlations do not prove causation. This review provides a variety of studies showing short people have little to no cardiovascular disease. When shorter people are compared to taller people, a number of biological mechanisms evolve favoring shorter people, including reduced telomere shortening, lower atrial fibrillation, higher heart pumping efficiency, lower DNA damage, lower risk of blood clots, lower left ventricular hypertrophy and superior blood parameters. The causes of increased heart disease among shorter people in the developed world are related to lower income, excessive weight, poor diet, lifestyle factors, catch-up growth, childhood illness and poor environmental conditions. For short people in developed countries, the data indicate that a plant-based diet, leanness and regular exercise can substantially reduce the risk of cardiovascular disease.

  10. A Research of Construction Mechanism of Vassal State's City Group during Spring and Autumn Period Based on the Analyzation of Geographic Image - Take south region of Shandong as example

    Science.gov (United States)

    Gao, X.; Li, B.; Zhou, X.

    2015-08-01

    Spring and Autumn period, the vassal states began to carry out country defense construction actively, brought changes to building the ideological. At that time, the south region of Shandong, as an independent unit of geography, seldom affected by external factors, and had striking cultural characteristics. Vassal states there constructed their capital mainly to defense the neighboring countries and cope with small scale mergers war, not involving the nationwide military deployment. Therefore, the region reflect the construction thought changes during the Spring and Autumn Period, and consistent with the research purpose. Based on this judgment, the author analyzed each capital's location and terrain feature by topographic map. In brief, the Spring and Autumn Period, feudal states acted of one's own free will, the relationship between cities contained the one within and between vassal states. Within vassal state relationships included economic support, entrenching each other and protecting the country together. Meanwhile, strategic defensing, scrambling for resources and geographical location comprised of the competition between vassal states. In the agrarian age, the political centers and agricultural areas were interdependent, giving priority to the development of political cities. Transformation of capitals' space layout was actually the process of carving up farming plains, the powerful states occupy favorable geographical position, and the small countries would be encroached and annexed gradually.

  11. Design and construction of focusing lens to be applied to the XRF analysis. Final report for the period 1 December 1993 - 30 November 1995

    International Nuclear Information System (INIS)

    Yan Yiming

    1996-01-01

    The construction and performance test for assembled and monolithic lenses have been done. Experimental setups and procedures for the determination of focussing capability of the lenses (diameter of the X-ray beam), beam profile at the focal plane, and transmission efficiency were designed and provided the necessary data. The results of the test of both lenses (assembled and monolithic) are good. The fact that the monolithic lens is significantly better as far as the spot size and gain factor are concerned, proves the advantages of the new technology for production of focussing optics for XRF analysis. The spot size of X-ray microbeam (200 μm) is adequate for many applications of XRF technique for trace element determination with both advantageous detection limits and imaging capability

  12. THE CONSTRUCTION OF PHYSICAL REHABILITATION PROGRAMS IN THE PREOPERATIVE PERIOD FOR PATIENTS THAT WILL REMOVE OF INTERVERTEBRAL DISC’ PROLAPSE IN THE LUMBAR SPINE

    Directory of Open Access Journals (Sweden)

    E.B. Lazarieva

    2014-06-01

    Full Text Available The ineffectiveness of conservative treatment will make the need for surgery in 4-5% of patients suffering from low back pain with hernias of the lumbar and sacral spine. Despite the surgical removal of the source of compressed roots, nerves and blood vessels, require a comprehensive system of rehabilitation therapy in order to eliminate manifestations of disease and relief of disease progression. The aim of the work is to substantiate the general approaches for the using of physical rehabilitation and diagnostics static component of the dynamic stereotype in the preoperative period in patients to remove intervertebral disc prolapse. The materials and methods. There was examined 96 with low back pain. Methods are applied in this research: analysis of a literature, observation methods. Results. In conjunction with the physician was determined "diagnosis for rehabilitation" and "prognosis of the rehabilitation". The formulation of the basis of the diagnosis for rehabilitation was performed through the examination during the rehabilitation (as a taking an anamnestic data, examination and palpation, studies of intact sensory and motor functions, the results of objective research tool. Conclusions. The identification of preserved anatomical and functional entities, the definition of the initial level of compensation for lost functions and forecast further recovery is a fundamental approach to program development in the preoperative period in patients with low back pain aimed at the removal of intervertebral disc herniations.

  13. Extending 3D near-cloud corrections from shorter to longer wavelengths

    International Nuclear Information System (INIS)

    Marshak, Alexander; Evans, K. Frank; Várnai, Tamás; Wen, Guoyong

    2014-01-01

    Satellite observations have shown a positive correlation between cloud amount and aerosol optical thickness (AOT) that can be explained by the humidification of aerosols near clouds, and/or by cloud contamination by sub-pixel size clouds and the cloud adjacency effect. The last effect may substantially increase reflected radiation in cloud-free columns, leading to overestimates in the retrieved AOT. For clear-sky areas near boundary layer clouds the main contribution to the enhancement of clear sky reflectance at shorter wavelengths comes from the radiation scattered into clear areas by clouds and then scattered to the sensor by air molecules. Because of the wavelength dependence of air molecule scattering, this process leads to a larger reflectance increase at shorter wavelengths, and can be corrected using a simple two-layer model [18]. However, correcting only for molecular scattering skews spectral properties of the retrieved AOT. Kassianov and Ovtchinnikov [9] proposed a technique that uses spectral reflectance ratios to retrieve AOT in the vicinity of clouds; they assumed that the cloud adjacency effect influences the spectral ratio between reflectances at two wavelengths less than it influences the reflectances themselves. This paper combines the two approaches: It assumes that the 3D correction for the shortest wavelength is known with some uncertainties, and then it estimates the 3D correction for longer wavelengths using a modified ratio method. The new approach is tested with 3D radiances simulated for 26 cumulus fields from Large-Eddy Simulations, supplemented with 40 aerosol profiles. The results showed that (i) for a variety of cumulus cloud scenes and aerosol profiles over ocean the 3D correction due to cloud adjacency effect can be extended from shorter to longer wavelengths and (ii) the 3D corrections for longer wavelengths are not very sensitive to unbiased random uncertainties in the 3D corrections at shorter wavelengths. - Highlights:

  14. YAOPBM-II: extension to higher degrees and to shorter time series

    Energy Technology Data Exchange (ETDEWEB)

    Korzennik, S G [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (United States)], E-mail: skorzennik@cfa.harvard.edu

    2008-10-15

    In 2005, I presented a new fitting methodology (Yet AnOther Peak Bagging Method -YAOPBM), derived for very-long time series (2088-day-long) and applied it to low degree modes, {iota} {<=} 25. That very-long time series was also sub-divided into shorter segments (728-day-long) that were each fitted over the same range of degrees, to estimate changes with solar activity levels. I present here the extension of this method in several 'directions': a) to substantially higher degrees ({iota} {<=} 125); b) to shorter time series (364- and 182-day-long); and c) to additional 728-day-long segments, covering now some 10 years of observations. I discuss issues with the fitting, namely the leakage matrix, and the f- and p1 mode at very low frequencies, and I present some of the characteristics of the observed temporal changes.

  15. Is equity confined to the shorter term projects - and if not, what does it need?

    International Nuclear Information System (INIS)

    Cryan, T.

    1996-01-01

    There are two types of equity investor generally found in shorter term energy projects: energy project developers or sponsors who view a given project as buying or building a business; and financial investors who have viewed an investment as buying a stream of cash flows. This article examines the objectives and needs of these two investor groups, and discusses the principal issues which govern their respective decision-making process. (author)

  16. How do shorter working hours affect employee wellbeing? : Shortening working time in Finland

    OpenAIRE

    Lahdenperä, Netta

    2017-01-01

    The way work is done is dramatically changing due to digital breakthroughs. Generation Y is entering the workforce with a changed attitude towards work as organizations are increasing their focus towards employee wellbeing. Organizations who adopt the new model of work and understand the importance of the wellbeing of their staff are leading the transition to a more efficient business, better working life and a healthier planet. The thesis explores the numerous effects of shorter working...

  17. USAID Construction Assessment

    Data.gov (United States)

    US Agency for International Development — The USAID construction assessment is a survey of the character, scope, value and management of construction activities supported by USAID during the period from June...

  18. Investigation of Industrialised Building System Performance in Comparison to Conventional Construction Method

    Directory of Open Access Journals (Sweden)

    Othuman Mydin M.A.

    2014-03-01

    Full Text Available Conventional construction methods are still widely practised, although many researches have indicated that this method is less effective compared to the IBS construction method. The existence of the IBS has added to the many techniques within the construction industry. This study is aimed at making comparisons between the two construction approaches. Case studies were conducted at four sites in the state of Penang, Malaysia. Two projects were IBS-based while the remaining two deployed the conventional method of construction. Based on an analysis of the results, it can be concluded that the IBS approach has more to offer compared to the conventional method. Among these advantages are shorter construction periods, reduced overall costs, less labour needs, better site conditions and the production of higher quality components.

  19. Physical activity during video capsule endoscopy correlates with shorter bowel transit time.

    Science.gov (United States)

    Stanich, Peter P; Peck, Joshua; Murphy, Christopher; Porter, Kyle M; Meyer, Marty M

    2017-09-01

     Video capsule endoscopy (VCE) is limited by reliance on bowel motility for propulsion, and lack of physical activity has been proposed as a cause of incomplete studies. Our aim was to prospectively investigate the association between physical activity and VCE bowel transit.  Ambulatory outpatients receiving VCE were eligible for the study. A pedometer was attached at the time of VCE ingestion and step count was recorded at the end of the procedure. VCE completion was assessed by logistic regression models, which included step count (500 steps as one unit). Total transit time was analyzed by Cox proportional hazards models. The hazard ratios (HR) with 95 % confidence interval (CI) indicated the "hazard" of completion, such that HRs > 1 indicated a reduced transit time.  A total of 100 patients were included. VCE was completed in 93 patients (93 %). The median step count was 2782 steps. Step count was not significantly associated with VCE completion (odds ratio 1.45, 95 %CI 0.84, 2.49). Pedometer step count was significantly associated with shorter total, gastric, and small-bowel transit times (HR 1.09, 95 %CI 1.03, 1.16; HR 1.05, 95 %CI 1.00, 1.11; HR 1.07, 95 %CI 1.01, 1.14, respectively). Higher body mass index (BMI) was significantly associated with VCE completion (HR 1.87, 95 %CI 1.18, 2.97) and shorter bowel transit times (HR 1.05, 95 %CI 1.02, 1.08).  Increased physical activity during outpatient VCE was associated with shorter bowel transit times but not with study completion. In addition, BMI was a previously unreported clinical characteristic associated with VCE completion and should be included as a variable of interest in future studies.

  20. Homework schedule: an important factor associated with shorter sleep duration among Chinese school-aged children.

    Science.gov (United States)

    Li, Shenghui; Yang, Qian; Chen, Zhe; Jin, Xingming; Jiang, Fan; Shen, Xiaoming

    2014-09-03

    This study was designed to examine the hypothesis that homework schedule has adverse impacts on Chinese children's sleep-wake habits and sleep duration. A random sample of 19,299 children aged 5.08 to 11.99 years old participated in a large, cross-sectional survey. A parent-administered questionnaire was completed to quantify children's homework schedule and sleep behaviors. Generally, it was demonstrated that more homework schedule was significantly associated with later bedtime, later wake time, and shorter sleep duration. Among all sleep variables, bedtime and sleep duration during weekdays appeared to be most affected by homework schedule, especially homework schedule during weekdays.

  1. Reemission spectra and inelastic processes at interaction of attosecond and shorter duration electromagnetic pulses with atoms

    International Nuclear Information System (INIS)

    Makarov, D.N.; Matveev, V.I.

    2017-01-01

    Inelastic processes and the reemission of attosecond and shorter electromagnetic pulses by atoms have been considered within the analytical solution of the Schrödinger equation in the sudden perturbation approximation. A method of calculations with the exact inclusion of spatial inhomogeneity of the field of an ultrashort pulse and the momenta of photons in the reemission processes has been developed. The probabilities of inelastic processes and spectra of reemission of ultrashort electromagnetic pulses by one- and many-electron atoms have been calculated. The results have been presented in the form of analytical formulas.

  2. Shorter preschool, leukocyte telomere length is associated with obesity at age 9 in Latino children.

    Science.gov (United States)

    Kjaer, T W; Faurholt-Jepsen, D; Mehta, K M; Christensen, V B; Epel, E; Lin, J; Blackburn, E; Wojcicki, J M

    2018-04-01

    The aim of this study was to determine the potential role of leukocyte telomere length as a biomarker for development of childhood obesity in a low-income Latino population. A birth cohort of Latino children (N = 201) in San Francisco (recruited May 2006-May 2007) was followed until age 9 and assessed annually for obesity and dietary intake. Leukocyte telomere length was measured at 4 and 5 years (n = 102) and assessed as a predictor for obesity at age 9, adjusting for known risk factors. Furthermore, leukocyte telomere length at age 4 and 5 was evaluated as a possible mediator of the relationship between excessive sugar-sweetened beverage consumption and obesity at age 9. Shorter leukocyte telomere length in preschoolers was associated with obesity at age 9 (adjusted odds ratio 0.35, 95% confidence interval 0.13-0.94) after adjustment for known risk factors. Telomere length mediated 11% of the relationship between excessive sugar-sweetened beverage consumption and obesity. Shorter leukocyte telomere length may be an indicator of future obesity risk in high-risk populations as it is particularly sensitive to damage from oxidative stress exposure, including those from sugar-sweetened beverages. © 2017 World Obesity Federation.

  3. Applicability of the shorter ‘Bangladesh regimen’ in high multidrug-resistant tuberculosis settings

    Directory of Open Access Journals (Sweden)

    Giovanni Sotgiu

    2017-03-01

    Full Text Available In spite of the recent introduction of two new drugs (delamanid and bedaquiline and a few repurposed compounds to treat multidrug-resistant and extensively drug-resistant tuberculosis (MDR- and XDR-TB, clinicians are facing increasing problems in designing effective regimens in severe cases. Recently a 9 to 12-month regimen (known as the ‘Bangladesh regimen’ proved to be effective in treating MDR-TB cases. It included an initial phase of 4 to 6 months of kanamycin, moxifloxacin, prothionamide, clofazimine, pyrazinamide, high-dose isoniazid, and ethambutol, followed by 5 months of moxifloxacin, clofazimine, pyrazinamide, and ethambutol. However, recent evidence from Europe and Latin America identified prevalences of resistance to the first-line drugs in this regimen (ethambutol and pyrazinamide exceeding 60%, and of prothionamide exceeding 50%. Furthermore, the proportions of resistance to the two most important pillars of the regimen – quinolones and kanamycin – were higher than 40%. Overall, only 14 out of 348 adult patients (4.0% were susceptible to all of the drugs composing the regimen, and were therefore potentially suitable for the ‘shorter regimen’. A shorter, cheaper, and well-tolerated MDR-TB regimen is likely to impact the number of patients treated and improve adherence if prescribed to the right patients through the systematic use of rapid MTBDRsl testing.

  4. Representativeness of shorter measurement sessions in long-term indoor air monitoring.

    Science.gov (United States)

    Maciejewska, M; Szczurek, A

    2015-02-01

    Indoor air quality (IAQ) considerably influences health, comfort and the overall performance of people who spend most of their lives in confined spaces. For this reason, there is a strong need to develop methods for IAQ assessment. The fundamental issue in the quantitative determination of IAQ is the duration of measurements. Its inadequate choice may result in providing incorrect information and this potentially leads to wrong conclusions. The most complete information may be acquired through long-term monitoring. However it is typically perceived as impractical due to time and cost load. The aim of this study was to determine whether long-term monitoring can be adequately represented by a shorter measurement session. There were considered three measurable quantities: temperature, relative humidity and carbon dioxide concentration. They are commonly recognized as indicatives for IAQ and may be readily monitored. Scaled Kullback-Leibler divergence, also called relative entropy, was applied as a measure of data representativeness. We considered long-term monitoring in a range from 1 to 9 months. Based on our work, the representative data on CO2 concentration may be acquired while performing measurements during 20% of time dedicated to long-term monitoring. In the case of temperature and relative humidity the respective time demand was 50% of long-term monitoring. From our results, in indoor air monitoring strategies, there could be considered shorter measurement sessions, while still collecting data which are representative for long-term monitoring.

  5. Are Shorter Versions of the Positive and Negative Syndrome Scale (PANSS) Doable? A Critical Review.

    Science.gov (United States)

    Lindenmayer, Jean-Pierre

    2017-12-01

    The Positive and Negative Syndrome Scale (PANSS) is a well-established assessment tool for measuring symptom severity in schizophrenia. Researchers and clinicians have been interested in the development of a short version of the PANSS that could reduce the burden of its administration for patients and raters. The author presents a comprehensive overview of existing brief PANSS measures, including their strengths and limitations, and discusses some possible next steps. There are two available scales that offer a reduced number of original PANSS items: PANSS-14 and PANSS-19; and two shorter versions that include six items: Brief PANSS and PANSS-6. The PANSS-6 has been tested quite extensively in established trials and appears to demonstrate high sensitivity to change and an established cut off definition for remission. Prospective testing in new antipsychotic treatment trials is still required for these shorter versions of PANSS. In addition, they need to be supplemented with interview guides, as well as provide conversion formulas to translate total scores from the short PANSS versions to the PANSS-30. Both short versions of the PANSS are essentially designed to evaluate response to antipsychotic treatment. Future PANSS scale development needs to address specific measurement of treatment-responsive positive symptoms by including treatment-sensitive items, as well as illness-phase specific PANSS tools.

  6. Construction time of PWRs

    International Nuclear Information System (INIS)

    Moreira, João M.L.; Gallinaro, Bruno; Carajilescov, Pedro

    2013-01-01

    The construction time of PWRs is studied considering published data about nuclear power plants in the world. For the 268 PWRs in operation in 2010, the mode of the construction time distribution is around 5–6 years, and 80% of the plants were built in less than 120 months. To circumvent the problem of comparing plants with different size we normalized the construction time to plants with 1 GW. We restricted the analysis to 201 PWRs which suffered less from external factors that were beyond the control of the management from 1965 to 2010. The results showed that the normalized construction time did not increase over the years and nor with the plants’ gross power level. The learning rate of the industry regarding normalized construction times showed a reduction with 95% confidence level of about 0.56±0.07 months for each 10 GW of installed capacity. Over the years the normalized construction time decreased and became more predictable. The data showed that countries with more centralized regulatory, construction and operation environments were able to build PWRs in shorter times. Countries less experienced with the nuclear technology built PWRs in longer times. - Highlights: ► The construction time of PWRs is analyzed based on historical data. ► Different factors affecting construction time are considered in the analyses. ► The normalized construction time of PWRs decreased with time and gross power level. ► Countries with more centralized institutions built PWRs more quickly

  7. Construction time of PWRs

    Energy Technology Data Exchange (ETDEWEB)

    Carajilescov, Pedro; Moreira, Joao M.L., E-mail: pedro.carajilescov@ufabc.edu.b, E-mail: joao.moreira@ufabc.edu.b [Universidade Federal do ABC (UFABC), Santo Andre, SP (Brazil). Center of Engineering, Modeling and Applied Social Sciences

    2011-07-01

    The cost of electricity generated by nuclear power is greatly affected by the capital cost, which is dependent on the construction time of the plant. This work analyses the construction time of PWRs in several countries with different market structure and licensing experience. Countries which succeeded to establish a more collaborative environment among utilities, constructors, regulators, and energy planners through effective partnerships were able to build PWRs in shorter times. The construction time in Germany, France and Russia was around 80 months and in Japan, about 60 months. The envelope of 95% of the cases includes a range between 50 and 250 months of construction time. The evaluations show that construction time of PWRs has been longer for countries that did not hold the technology to build their own reactors, and depended on contracts with foreign suppliers. The nominal power of the reactors was considered a measure of plant size, technology complexity and standardization. Countries with standardized reactor designs (France, Japan and Russia) were able to build plants in shorter times. (author)

  8. Construction time of PWRs

    International Nuclear Information System (INIS)

    Carajilescov, Pedro; Moreira, Joao M.L.

    2011-01-01

    The cost of electricity generated by nuclear power is greatly affected by the capital cost, which is dependent on the construction time of the plant. This work analyses the construction time of PWRs in several countries with different market structure and licensing experience. Countries which succeeded to establish a more collaborative environment among utilities, constructors, regulators, and energy planners through effective partnerships were able to build PWRs in shorter times. The construction time in Germany, France and Russia was around 80 months and in Japan, about 60 months. The envelope of 95% of the cases includes a range between 50 and 250 months of construction time. The evaluations show that construction time of PWRs has been longer for countries that did not hold the technology to build their own reactors, and depended on contracts with foreign suppliers. The nominal power of the reactors was considered a measure of plant size, technology complexity and standardization. Countries with standardized reactor designs (France, Japan and Russia) were able to build plants in shorter times. (author)

  9. Shorter epilepsy duration is associated with better seizure outcome in temporal lobe epilepsy surgery

    Directory of Open Access Journals (Sweden)

    Lucas Crociati Meguins

    2015-03-01

    Full Text Available Objective To investigate the influence of patient’s age and seizure onset on surgical outcome of temporal lobe epilepsy (TLE. Method A retrospective observational investigation performed from a cohort of patients from 2000 to 2012. Results A total of 229 patients were included. One-hundred and eleven of 179 patients (62% were classified as Engel I in the group with < 50 years old, whereas 33 of 50 (66% in the group with ≥ 50 years old group (p = 0.82. From those Engel I, 88 (61% reported epilepsy duration inferior to 10 years and 56 (39% superior to 10 years (p < 0.01. From the total of patients not seizure free, 36 (42% reported epilepsy duration inferior to 10 years and 49 (58% superior to 10 years (p < 0.01. Conclusion Patients with shorter duration of epilepsy before surgery had better postoperative seizure control than patients with longer duration of seizures.

  10. Association of mutations in the hemochromatosis gene with shorter life expectancy

    DEFF Research Database (Denmark)

    Bathum, L; Christiansen, L; Nybo, H

    2001-01-01

    BACKGROUND: To investigate whether the frequency of carriers of mutations in the HFE gene associated with hereditary hemochromatosis diminishes with age as an indication that HFE mutations are associated with increased mortality. It is of value in the debate concerning screening for hereditary...... hemochromatosis to determine the significance of heterozygosity. METHODS: Genotyping for mutations in exons 2 and 4 of the HFE gene using denaturing gradient gel electrophoresis in 1784 participants aged 45 to 100 years from 4 population-based studies: all 183 centenarians from the Danish Centenarian Study, 601...... in the distribution of mutations in exon 2 in the different age groups. CONCLUSIONS: In a high-carrier frequency population like Denmark, mutations in HFE show an age-related reduction in the frequency of heterozygotes for C282Y, which suggests that carrier status is associated with shorter life expectancy....

  11. Shorter preschool, leukocyte telomere length is associated with obesity at age 9 in Latino children

    DEFF Research Database (Denmark)

    Kjaer, Thora Wesenberg; Faurholt-Jepsen, D; Mehta, K M

    2018-01-01

    The aim of this study was to determine the potential role of leukocyte telomere length as a biomarker for development of childhood obesity in a low-income Latino population. A birth cohort of Latino children (N = 201) in San Francisco (recruited May 2006-May 2007) was followed until age 9...... and assessed annually for obesity and dietary intake. Leukocyte telomere length was measured at 4 and 5 years (n = 102) and assessed as a predictor for obesity at age 9, adjusting for known risk factors. Furthermore, leukocyte telomere length at age 4 and 5 was evaluated as a possible mediator...... of the relationship between excessive sugar-sweetened beverage consumption and obesity at age 9. Shorter leukocyte telomere length in preschoolers was associated with obesity at age 9 (adjusted odds ratio 0.35, 95% confidence interval 0.13-0.94) after adjustment for known risk factors. Telomere length mediated 11...

  12. Hereditary angioedema attacks resolve faster and are shorter after early icatibant treatment.

    Directory of Open Access Journals (Sweden)

    Marcus Maurer

    Full Text Available BACKGROUND: Attacks of hereditary angioedema (HAE are unpredictable and, if affecting the upper airway, can be lethal. Icatibant is used for physician- or patient self-administered symptomatic treatment of HAE attacks in adults. Its mode of action includes disruption of the bradykinin pathway via blockade of the bradykinin B(2 receptor. Early treatment is believed to shorten attack duration and prevent severe outcomes; however, evidence to support these benefits is lacking. OBJECTIVE: To examine the impact of timing of icatibant administration on the duration and resolution of HAE type I and II attacks. METHODS: The Icatibant Outcome Survey is an international, prospective, observational study for patients treated with icatibant. Data on timings and outcomes of icatibant treatment for HAE attacks were collected between July 2009-February 2012. A mixed-model of repeated measures was performed for 426 attacks in 136 HAE type I and II patients. RESULTS: Attack duration was significantly shorter in patients treated <1 hour of attack onset compared with those treated ≥ 1 hour (6.1 hours versus 16.8 hours [p<0.001]. Similar significant effects were observed for <2 hours versus ≥ 2 hours (7.2 hours versus 20.2 hours [p<0.001] and <5 hours versus ≥ 5 hours (8.0 hours versus 23.5 hours [p<0.001]. Treatment within 1 hour of attack onset also significantly reduced time to attack resolution (5.8 hours versus 8.8 hours [p<0.05]. Self-administrators were more likely to treat early and experience shorter attacks than those treated by a healthcare professional. CONCLUSION: Early blockade of the bradykinin B(2 receptor with icatibant, particularly within the first hour of attack onset, significantly reduced attack duration and time to attack resolution.

  13. ATM/RB1 mutations predict shorter overall survival in urothelial cancer.

    Science.gov (United States)

    Yin, Ming; Grivas, Petros; Emamekhoo, Hamid; Mendiratta, Prateek; Ali, Siraj; Hsu, JoAnn; Vasekar, Monali; Drabick, Joseph J; Pal, Sumanta; Joshi, Monika

    2018-03-30

    Mutations of DNA repair genes, e.g. ATM/RB1 , are frequently found in urothelial cancer (UC) and have been associated with better response to cisplatin-based chemotherapy. Further external validation of the prognostic value of ATM/RB1 mutations in UC can inform clinical decision making and trial designs. In the discovery dataset, ATM/RB1 mutations were present in 24% of patients and were associated with shorter OS (adjusted HR 2.67, 95% CI, 1.45-4.92, p = 0.002). There was a higher mutation load in patients carrying ATM/RB1 mutations (median mutation load: 6.7 versus 5.5 per Mb, p = 0.072). In the validation dataset, ATM/RB1 mutations were present in 22.2% of patients and were non-significantly associated with shorter OS (adjusted HR 1.87, 95% CI, 0.97-3.59, p = 0.06) and higher mutation load (median mutation load: 8.1 versus 7.2 per Mb, p = 0.126). Exome sequencing data of 130 bladder UC patients from The Cancer Genome Atlas (TCGA) dataset were analyzed as a discovery cohort to determine the prognostic value of ATM/RB1 mutations. Results were validated in an independent cohort of 81 advanced UC patients. Cox proportional hazard regression analysis was performed to calculate the hazard ratio (HR) and 95% confidence interval (CI) to compare overall survival (OS). ATM/RB1 mutations may be a biomarker of poor prognosis in unselected UC patients and may correlate with higher mutational load. Further studies are required to determine factors that can further stratify prognosis and evaluate predictive role of ATM/RB1 mutation status to immunotherapy and platinum-based chemotherapy.

  14. Marital disruption is associated with shorter salivary telomere length in a probability sample of older adults.

    Science.gov (United States)

    Whisman, Mark A; Robustelli, Briana L; Sbarra, David A

    2016-05-01

    Marital disruption (i.e., marital separation, divorce) is associated with a wide range of poor mental and physical health outcomes, including increased risk for all-cause mortality. One biological intermediary that may help explain the association between marital disruption and poor health is accelerated cellular aging. This study examines the association between marital disruption and salivary telomere length in a United States probability sample of adults ≥50 years of age. Participants were 3526 individuals who participated in the 2008 wave of the Health and Retirement Study. Telomere length assays were performed using quantitative real-time polymerase chain reaction (qPCR) on DNA extracted from saliva samples. Health and lifestyle factors, traumatic and stressful life events, and neuroticism were assessed via self-report. Linear regression analyses were conducted to examine the associations between predictor variables and salivary telomere length. Based on their marital status data in the 2006 wave, people who were separated or divorced had shorter salivary telomeres than people who were continuously married or had never been married, and the association between marital disruption and salivary telomere length was not moderated by gender or neuroticism. Furthermore, the association between marital disruption and salivary telomere length remained statistically significant after adjusting for demographic and socioeconomic variables, neuroticism, cigarette use, body mass, traumatic life events, and other stressful life events. Additionally, results revealed that currently married adults with a history of divorce evidenced shorter salivary telomeres than people who were continuously married or never married. Accelerated cellular aging, as indexed by telomere shortening, may be one pathway through which marital disruption is associated with morbidity and mortality. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Analysis of the Problems and Countermeasures in Teacher Ethics Construction of Social Transformation Period%社会转型期高校师德师风建设问题与对策探析

    Institute of Scientific and Technical Information of China (English)

    王文中

    2014-01-01

    社会转型时期,多元化的价值观念冲击着高校校园,高校师德师风建设面临全新的挑战,高校师德出现学术功利化、缺乏奉献与合作创新精神等滑坡现象,文章通过对其现状和原因的分析认为可采取加强教师思想道德教育,构建公正合理的学术评价体系及具体量化的师德评价体系等三方面的对策来加强和改善。%Diversified values of social transformation period are sweeping the university campuses , posing new challenges to university teacher ethics construction . Through analysis of the causes to such problems in teacher ethics as academic utilitarianism , lack of dedication , and poor cooperation and innovation , this thesis holds that teacher ethics can be improved and consolidated from three aspects: strengthening ideological and moral education , establishing fair and reasonable academic evaluation system , and constructing specific and quantitive teacher ethics assessment system .

  16. Minimally invasive oesophagectomy more expensive than open despite shorter length of stay.

    Science.gov (United States)

    Dhamija, Anish; Dhamija, Ankit; Hancock, Jacquelyn; McCloskey, Barbara; Kim, Anthony W; Detterbeck, Frank C; Boffa, Daniel J

    2014-05-01

    The minimally invasive oesophagectomy (MIO) approach offers a number of advantages over open approaches including reduced discomfort, shorter length of stay and a faster recovery to baseline status. On the other hand, minimally invasive procedures typically are longer and consume greater disposable instrumentation, potentially resulting in a greater overall cost. The objective of this study was to compare costs associated with various oesophagectomy approaches for oesophageal cancer. An institutional Resource Information Management System (RIMS) was queried for cost data relating to hospital expenditures (as opposed to billings or collections). The RIMS was searched for patients undergoing oesophagectomy for oesophageal cancer between 2003 and 2012 via minimally invasive, open transthoracic (OTT) (including Ivor Lewis, modified McKeown or thoracoabdominal) or transhiatal approaches. Patients that were converted from minimally invasive to open, or involved hybrid procedures, were excluded. A total of 160 oesophagectomies were identified, including 61 minimally invasive, 35 open transthoracic and 64 transhiatal. Costs on the day of surgery averaged higher in the MIO group ($12 476 ± 2190) compared with the open groups, OTT ($8202 ± 2512, P < 0.0001) or OTH ($5809 ± 2575, P < 0.0001). The median costs associated with the entire hospitalization also appear to be higher in the MIO group ($25 935) compared with OTT ($24 440) and OTH ($15 248). The average length of stay was lowest in the MIO group (11 ± 9 days) compared with OTT (19 ± 18 days, P = 0.006) and OTH (18 ± 28 days P = 0.07). The operative mortality was similar in the three groups (MIO = 3%, OTT = 9% and OTH = 3%). The operating theatre costs associated with minimally invasive oesophagectomy are significantly higher than OTT or OTH approaches. Unfortunately, a shorter hospital stay after MIO does not consistently offset higher surgical expense, as total hospital costs trend higher in the MIO patients. In

  17. Prefabrication in Building Construction: A Perspective of Pakistan Construction Industry

    Directory of Open Access Journals (Sweden)

    Nafees Ahmed Memon

    2014-07-01

    Full Text Available Construction industry is facing many problems in terms of construction waste, quality, environment, durability, safety and higher construction cost. Adoption of prefabrication is a possible solution to such problems. Accordingly, there is a need to study the prospects that would stimulate the appropriate discussion of the suitability of prefabrication and other construction methods for concrete buildings. Therefore, this study investigates the significance of advantages in adopting prefabrication along with hindrances through questionnaire survey. The data has been analyzed using RIW (Relative Importance Weight method as a MCDM approach. The results depict that main advantages of prefabrication are ?Shorter construction time? and ?Less construction site waste?. The top hindrances in adopting prefabrication as identified in this study are: ?Higher initial construction cost? and ?Inflexible for design changes?. Based on the survey results and apparent progress in the adoption of prefabrication around the world, it is concluded that the use of prefabrication is likely to increase in developing countries like Pakistan

  18. Prefabrication in building construction: a perspective of pakistan construction industry

    International Nuclear Information System (INIS)

    Memon, N.A.; Memon, F.A.; Khehro, S.H.

    2014-01-01

    Construction industry is facing many problems in terms of construction waste, quality, environment, durability, safety and higher construction cost. Adoption of prefabrication is a possible solution to such problems. Accordingly, there is a need to study the prospects that would stimulate the appropriate discussion of the suitability of prefabrication and other construction methods for concrete buildings. Therefore, this study investigates the significance of advantages in adopting prefabrication along with hindrances through questionnaire survey. The data has been analyzed using RIW (Relative Importance Weight) method as a MCDM approach. The results depict that main advantages of prefabrication are Shorter construction time and Less construction site waste. The top hindrances in adopting prefabrication as identified in this study are: Higher initial construction cost and Inflexible for design changes. Based on the survey results and apparent progress in the adoption of prefabrication around the world, it is concluded that the use of prefabrication is likely to increase in developing countries like Pakistan. (author)

  19. "Taller and Shorter": Human 3-D Spatial Memory Distorts Familiar Multilevel Buildings.

    Directory of Open Access Journals (Sweden)

    Thomas Brandt

    Full Text Available Animal experiments report contradictory findings on the presence of a behavioural and neuronal anisotropy exhibited in vertical and horizontal capabilities of spatial orientation and navigation. We performed a pointing experiment in humans on the imagined 3-D direction of the location of various invisible goals that were distributed horizontally and vertically in a familiar multilevel hospital building. The 21 participants were employees who had worked for years in this building. The hypothesis was that comparison of the experimentally determined directions and the true directions would reveal systematic inaccuracy or dimensional anisotropy of the localizations. The study provides first evidence that the internal representation of a familiar multilevel building was distorted compared to the dimensions of the true building: vertically 215% taller and horizontally 51% shorter. This was not only demonstrated in the mathematical reconstruction of the mental model based on the analysis of the pointing experiments but also by the participants' drawings of the front view and the ground plan of the building. Thus, in the mental model both planes were altered in different directions: compressed for the horizontal floor plane and stretched for the vertical column plane. This could be related to human anisotropic behavioural performance of horizontal and vertical navigation in such buildings.

  20. Risky family processes prospectively forecast shorter telomere length mediated through negative emotions.

    Science.gov (United States)

    Brody, Gene H; Yu, Tianyi; Shalev, Idan

    2017-05-01

    This study was designed to examine prospective associations of risky family environments with subsequent levels of negative emotions and peripheral blood mononuclear cell telomere length (TL), a marker of cellular aging. A second purpose was to determine whether negative emotions mediate the hypothesized link between risky family processes and diminished telomere length. Participants were 293 adolescents (age 17 years at the first assessment) and their primary caregivers. Caregivers provided data on risky family processes when the youths were age 17 years, youths reported their negative emotions at age 18 years, and youths' TL was assayed from a blood sample at age 22 years. The results revealed that (a) risky family processes forecast heightened negative emotions (β = .316, p emotions forecast shorter TL (β = -.187, p = .012), and (c) negative emotions served as a mediator connecting risky family processes with diminished TL (indirect effect = -0.012, 95% CI [-0.036, -0.002]). These findings are consistent with the hypothesis that risky family processes presage premature cellular aging through effects on negative emotions, with potential implications for lifelong health. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  1. Effects of shorter versus longer storage time of transfused red blood cells in adult ICU patients

    DEFF Research Database (Denmark)

    Rygård, Sofie L; Jonsson, Andreas B; Madsen, Martin B

    2018-01-01

    on the effects of shorter versus longer storage time of transfused RBCs on outcomes in ICU patients. METHODS: We conducted a systematic review with meta-analyses and trial sequential analyses (TSA) of randomised clinical trials including adult ICU patients transfused with fresher versus older or standard issue...... blood. RESULTS: We included seven trials with a total of 18,283 randomised ICU patients; two trials of 7504 patients were judged to have low risk of bias. We observed no effects of fresher versus older blood on death (relative risk 1.04, 95% confidence interval (CI) 0.97-1.11; 7349 patients; TSA......-adjusted CI 0.93-1.15), adverse events (1.26, 0.76-2.09; 7332 patients; TSA-adjusted CI 0.16-9.87) or post-transfusion infections (1.07, 0.96-1.20; 7332 patients; TSA-adjusted CI 0.90-1.27). The results were unchanged by including trials with high risk of bias. TSA confirmed the results and the required...

  2. Gain of chromosome arm 1q in atypical meningioma correlates with shorter progression-free survival.

    LENUS (Irish Health Repository)

    2012-02-01

    Aims: Atypical (WHO grade II) meningiomas have moderately high recurrence rates; even for completely resected tumours, approximately one-third will recur. Post-operative radiotherapy (RT) may aid local control and improve survival, but carries the risk of side effects. More accurate prediction of recurrence risk is therefore needed for patients with atypical meningioma. Previously, we used high-resolution array CGH to identify genetic variations in 47 primary atypical meningiomas and found that approximately 60% of tumors show gain of 1q at 1q25.1 and 1q25.3 to 1q32.1 and that 1q gain appeared to correlate with shorter progression-free survival. This study aimed to validate and extend these findings in an independent sample. Methods: 86 completely resected atypical meningiomas (with 25 recurrences) from two neurosurgical centres in Ireland were identified and clinical follow up was obtained. Utilizing a dual-colour interphase FISH assay, 1q gain was assessed using BAC probes directed against 1q25.1 and 1q32.1. Results: The results confirm the high prevalence of 1q gain at these loci in atypical meningiomas. We further show that gain at 1q32.1 and age each correlate with progression-free survival in patients who have undergone complete surgical resection of atypical meningiomas. Conclusions: These independent findings suggest that assessment of 1q copy number status can add clinically useful information for the management of patients with atypical meningiomas.

  3. Greater reproductive investment, but shorter lifespan, in agrosystem than in natural-habitat toads

    Directory of Open Access Journals (Sweden)

    Francisco Javier Zamora-Camacho

    2017-09-01

    Full Text Available Global amphibian decline is due to several factors: habitat loss, anthropization, pollution, emerging diseases, and global warming. Amphibians, with complex life cycles, are particularly susceptible to habitat alterations, and their survival may be impaired in anthropized habitats. Increased mortality is a well-known consequence of anthropization. Life-history theory predicts higher reproductive investment when mortality is increased. In this work, we compared age, body size, and different indicators of reproductive investment, as well as prey availability, in natterjack toads (Epidalea calamita from agrosystems and adjacent natural pine groves in Southwestern Spain. Mean age was lower in agrosystems than in pine groves, possibly as a consequence of increased mortality due to agrosystem environmental stressors. Remarkably, agrosystem toads were larger despite being younger, suggesting accelerated growth rate. Although we detected no differences in prey availability between habitats, artificial irrigation could shorten aestivation in agrosystems, thus increasing energy trade. Moreover, agrosystem toads exhibited increased indicators of reproductive investment. In the light of life-history theory, agrosystem toads might compensate for lesser reproductive events—due to shorter lives—with a higher reproductive investment in each attempt. Our results show that agrosystems may alter demography, which may have complex consequences on both individual fitness and population stability.

  4. "Taller and Shorter": Human 3-D Spatial Memory Distorts Familiar Multilevel Buildings.

    Science.gov (United States)

    Brandt, Thomas; Huber, Markus; Schramm, Hannah; Kugler, Günter; Dieterich, Marianne; Glasauer, Stefan

    2015-01-01

    Animal experiments report contradictory findings on the presence of a behavioural and neuronal anisotropy exhibited in vertical and horizontal capabilities of spatial orientation and navigation. We performed a pointing experiment in humans on the imagined 3-D direction of the location of various invisible goals that were distributed horizontally and vertically in a familiar multilevel hospital building. The 21 participants were employees who had worked for years in this building. The hypothesis was that comparison of the experimentally determined directions and the true directions would reveal systematic inaccuracy or dimensional anisotropy of the localizations. The study provides first evidence that the internal representation of a familiar multilevel building was distorted compared to the dimensions of the true building: vertically 215% taller and horizontally 51% shorter. This was not only demonstrated in the mathematical reconstruction of the mental model based on the analysis of the pointing experiments but also by the participants' drawings of the front view and the ground plan of the building. Thus, in the mental model both planes were altered in different directions: compressed for the horizontal floor plane and stretched for the vertical column plane. This could be related to human anisotropic behavioural performance of horizontal and vertical navigation in such buildings.

  5. The Effect of Shorter Treatment Regimens for Hepatitis C on Population Health and Under Fixed Budgets.

    Science.gov (United States)

    Morgan, Jake R; Kim, Arthur Y; Naggie, Susanna; Linas, Benjamin P

    2018-01-01

    Direct acting antiviral hepatitis C virus (HCV) therapies are highly effective but costly. Wider adoption of an 8-week ledipasvir/sofosbuvir treatment regimen could result in significant savings, but may be less efficacious compared with a 12-week regimen. We evaluated outcomes under a constrained budget and cost-effectiveness of 8 vs 12 weeks of therapy in treatment-naïve, noncirrhotic, genotype 1 HCV-infected black and nonblack individuals and considered scenarios of IL28B and NS5A resistance testing to determine treatment duration in sensitivity analyses. We developed a decision tree to use in conjunction with Monte Carlo simulation to investigate the cost-effectiveness of recommended treatment durations and the population health effect of these strategies given a constrained budget. Outcomes included the total number of individuals treated and attaining sustained virologic response (SVR) given a constrained budget and incremental cost-effectiveness ratios. We found that treating eligible (treatment-naïve, noncirrhotic, HCV-RNA budget among both black and nonblack individuals, and our results suggested that NS5A resistance testing is cost-effective. Eight-week therapy provides good value, and wider adoption of shorter treatment could allow more individuals to attain SVR on the population level given a constrained budget. This analysis provides an evidence base to justify movement of the 8-week regimen to the preferred regimen list for appropriate patients in the HCV treatment guidelines and suggests expanding that recommendation to black patients in settings where cost and relapse trade-offs are considered.

  6. MO-E-BRD-02: Accelerated Partial Breast Irradiation in Brachytherapy: Is Shorter Better?

    International Nuclear Information System (INIS)

    Todor, D.

    2015-01-01

    Is Non-invasive Image-Guided Breast Brachytherapy Good? – Jess Hiatt, MS Non-invasive Image-Guided Breast Brachytherapy (NIBB) is an emerging therapy for breast boost treatments as well as Accelerated Partial Breast Irradiation (APBI) using HDR surface breast brachytherapy. NIBB allows for smaller treatment volumes while maintaining optimal target coverage. Considering the real-time image-guidance and immobilization provided by the NIBB modality, minimal margins around the target tissue are necessary. Accelerated Partial Breast Irradiation in brachytherapy: is shorter better? - Dorin Todor, PhD VCU A review of balloon and strut devices will be provided together with the origins of APBI: the interstitial multi-catheter implant. A dosimetric and radiobiological perspective will help point out the evolution in breast brachytherapy, both in terms of devices and the protocols/clinical trials under which these devices are used. Improvements in imaging, delivery modalities and convenience are among the factors driving the ultrashort fractionation schedules but our understanding of both local control and toxicities associated with various treatments is lagging. A comparison between various schedules, from a radiobiological perspective, will be given together with a critical analysis of the issues. to review and understand the evolution and development of APBI using brachytherapy methods to understand the basis and limitations of radio-biological ‘equivalence’ between fractionation schedules to review commonly used and proposed fractionation schedules Intra-operative breast brachytherapy: Is one stop shopping best?- Bruce Libby, PhD. University of Virginia A review of intraoperative breast brachytherapy will be presented, including the Targit-A and other trials that have used electronic brachytherapy. More modern approaches, in which the lumpectomy procedure is integrated into an APBI workflow, will also be discussed. Learning Objectives: To review past and current

  7. Shorter Ground Contact Time and Better Running Economy: Evidence From Female Kenyan Runners.

    Science.gov (United States)

    Mooses, Martin; Haile, Diresibachew W; Ojiambo, Robert; Sang, Meshack; Mooses, Kerli; Lane, Amy R; Hackney, Anthony C

    2018-06-25

    Mooses, M, Haile, DW, Ojiambo, R, Sang, M, Mooses, K, Lane, AR, and Hackney, AC. Shorter ground contact time and better running economy: evidence from female Kenyan runners. J Strength Cond Res XX(X): 000-000, 2018-Previously, it has been concluded that the improvement in running economy (RE) might be considered as a key to the continued improvement in performance when no further increase in V[Combining Dot Above]O2max is observed. To date, RE has been extensively studied among male East African distance runners. By contrast, there is a paucity of data on the RE of female East African runners. A total of 10 female Kenyan runners performed 3 × 1,600-m steady-state run trials on a flat outdoor clay track (400-m lap) at the intensities that corresponded to their everyday training intensities for easy, moderate, and fast running. Running economy together with gait characteristics was determined. Participants showed moderate to very good RE at the first (202 ± 26 ml·kg·km) and second (188 ± 12 ml·kg·km) run trials, respectively. Correlation analysis revealed significant relationship between ground contact time (GCT) and RE at the second run (r = 0.782; p = 0.022), which represented the intensity of anaerobic threshold. This study is the first to report the RE and gait characteristics of East African female athletes measured under everyday training settings. We provided the evidence that GCT is associated with the superior RE of the female Kenyan runners.

  8. Less is more: latent learning is maximized by shorter training sessions in auditory perceptual learning.

    Science.gov (United States)

    Molloy, Katharine; Moore, David R; Sohoglu, Ediz; Amitay, Sygal

    2012-01-01

    The time course and outcome of perceptual learning can be affected by the length and distribution of practice, but the training regimen parameters that govern these effects have received little systematic study in the auditory domain. We asked whether there was a minimum requirement on the number of trials within a training session for learning to occur, whether there was a maximum limit beyond which additional trials became ineffective, and whether multiple training sessions provided benefit over a single session. We investigated the efficacy of different regimens that varied in the distribution of practice across training sessions and in the overall amount of practice received on a frequency discrimination task. While learning was relatively robust to variations in regimen, the group with the shortest training sessions (∼8 min) had significantly faster learning in early stages of training than groups with longer sessions. In later stages, the group with the longest training sessions (>1 hr) showed slower learning than the other groups, suggesting overtraining. Between-session improvements were inversely correlated with performance; they were largest at the start of training and reduced as training progressed. In a second experiment we found no additional longer-term improvement in performance, retention, or transfer of learning for a group that trained over 4 sessions (∼4 hr in total) relative to a group that trained for a single session (∼1 hr). However, the mechanisms of learning differed; the single-session group continued to improve in the days following cessation of training, whereas the multi-session group showed no further improvement once training had ceased. Shorter training sessions were advantageous because they allowed for more latent, between-session and post-training learning to emerge. These findings suggest that efficient regimens should use short training sessions, and optimized spacing between sessions.

  9. MO-E-BRD-02: Accelerated Partial Breast Irradiation in Brachytherapy: Is Shorter Better?

    Energy Technology Data Exchange (ETDEWEB)

    Todor, D. [Virginia Commonwealth University (United States)

    2015-06-15

    Is Non-invasive Image-Guided Breast Brachytherapy Good? – Jess Hiatt, MS Non-invasive Image-Guided Breast Brachytherapy (NIBB) is an emerging therapy for breast boost treatments as well as Accelerated Partial Breast Irradiation (APBI) using HDR surface breast brachytherapy. NIBB allows for smaller treatment volumes while maintaining optimal target coverage. Considering the real-time image-guidance and immobilization provided by the NIBB modality, minimal margins around the target tissue are necessary. Accelerated Partial Breast Irradiation in brachytherapy: is shorter better? - Dorin Todor, PhD VCU A review of balloon and strut devices will be provided together with the origins of APBI: the interstitial multi-catheter implant. A dosimetric and radiobiological perspective will help point out the evolution in breast brachytherapy, both in terms of devices and the protocols/clinical trials under which these devices are used. Improvements in imaging, delivery modalities and convenience are among the factors driving the ultrashort fractionation schedules but our understanding of both local control and toxicities associated with various treatments is lagging. A comparison between various schedules, from a radiobiological perspective, will be given together with a critical analysis of the issues. to review and understand the evolution and development of APBI using brachytherapy methods to understand the basis and limitations of radio-biological ‘equivalence’ between fractionation schedules to review commonly used and proposed fractionation schedules Intra-operative breast brachytherapy: Is one stop shopping best?- Bruce Libby, PhD. University of Virginia A review of intraoperative breast brachytherapy will be presented, including the Targit-A and other trials that have used electronic brachytherapy. More modern approaches, in which the lumpectomy procedure is integrated into an APBI workflow, will also be discussed. Learning Objectives: To review past and current

  10. Are Shorter Article Titles More Attractive for Citations? Cross-sectional Study of 22 Scientific Journals

    Science.gov (United States)

    Habibzadeh, Farrokh; Yadollahie, Mahboobeh

    2010-01-01

    Aim To investigate the correlation between the length of the title of a scientific article and the number of citations it receives, in view of the common editorial call for shorter titles. Methods Title and the number of citations to all articles published in 2005 in 22 arbitrarily chosen English-language journals (n = 9031) were retrieved from citation database Scopus. The 2008 journal impact factors of these 22 journals were also retrieved from Thomson Reuters’ Journal Citation Report (JCR). Assuming the article title length as the independent variable, and the number of citations to the article as the dependent variable, a linear regression model was applied. Results The slope of the regression line for some journals (n = 6, when titles were measured in characters but 7 when titles were measured in words) was negative – none was significantly different from 0. The overall slope for all journals was 0.140 (when titles were measured in characters) and 0.778 (when titles were measured in words), significantly different from 0 (P articles with longer titles received more citations – Spearman ρ = 0.266 – when titles were measured in characters, and ρ = 0.244 when titles were measured in words (P 10 and for 2 out of 14 journals with impact factor <10 (P < 0.001, Fisher exact test). Conclusion Longer titles seem to be associated with higher citation rates. This association is more pronounced for journals with high impact factors. Editors who insist on brief and concise titles should perhaps update the guidelines for authors of their journals and have more flexibility regarding the length of the title. PMID:20401960

  11. Shorter exposures to harder X-rays trigger early apoptotic events in Xenopus laevis embryos.

    Directory of Open Access Journals (Sweden)

    JiaJia Dong

    Full Text Available BACKGROUND: A long-standing conventional view of radiation-induced apoptosis is that increased exposure results in augmented apoptosis in a biological system, with a threshold below which radiation doses do not cause any significant increase in cell death. The consequences of this belief impact the extent to which malignant diseases and non-malignant conditions are therapeutically treated and how radiation is used in combination with other therapies. Our research challenges the current dogma of dose-dependent induction of apoptosis and establishes a new parallel paradigm to the photoelectric effect in biological systems. METHODOLOGY/PRINCIPAL FINDINGS: We explored how the energy of individual X-ray photons and exposure time, both factors that determine the total dose, influence the occurrence of cell death in early Xenopus embryo. Three different experimental scenarios were analyzed and morphological and biochemical hallmarks of apoptosis were evaluated. Initially, we examined cell death events in embryos exposed to increasing incident energies when the exposure time was preset. Then, we evaluated the embryo's response when the exposure time was augmented while the energy value remained constant. Lastly, we studied the incidence of apoptosis in embryos exposed to an equal total dose of radiation that resulted from increasing the incoming energy while lowering the exposure time. CONCLUSIONS/SIGNIFICANCE: Overall, our data establish that the energy of the incident photon is a major contributor to the outcome of the biological system. In particular, for embryos exposed under identical conditions and delivered the same absorbed dose of radiation, the response is significantly increased when shorter bursts of more energetic photons are used. These results suggest that biological organisms display properties similar to the photoelectric effect in physical systems and provide new insights into how radiation-mediated apoptosis should be understood and

  12. Feasibility of a shorter Goal Attainment Scaling method for a pediatric spasticity clinic - The 3-milestones GAS.

    Science.gov (United States)

    Krasny-Pacini, A; Pauly, F; Hiebel, J; Godon, S; Isner-Horobeti, M-E; Chevignard, M

    2017-07-01

    Goal Attainment Scaling (GAS) is a method for writing personalized evaluation scales to quantify progress toward defined goals. It is useful in rehabilitation but is hampered by the experience required to adequately "predict" the possible outcomes relating to a particular goal before treatment and the time needed to describe all 5 levels of the scale. Here we aimed to investigate the feasibility of using GAS in a clinical setting of a pediatric spasticity clinic with a shorter method, the "3-milestones" GAS (goal setting with 3 levels and goal rating with the classical 5 levels). Secondary aims were to (1) analyze the types of goals children's therapists set for botulinum toxin treatment and (2) compare the score distribution (and therefore the ability to predict outcome) by goal type. Therapists were trained in GAS writing and prepared GAS scales in the regional spasticity-management clinic they attended with their patients and families. The study included all GAS scales written during a 2-year period. GAS score distribution across the 5 GAS levels was examined to assess whether the therapist could reliably predict outcome and whether the 3-milestones GAS yielded similar distributions as the original GAS method. In total, 541 GAS scales were written and showed the expected score distribution. Most scales (55%) referred to movement quality goals and fewer (29%) to family goals and activity domains. The 3-milestones GAS method was feasible within the time constraints of the spasticity clinic and could be used by local therapists in cooperation with the hospital team. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  13. Shorter Hospital Stays and Lower Costs for Rivaroxaban Compared With Warfarin for Venous Thrombosis Admissions.

    Science.gov (United States)

    Margolis, Jay M; Deitelzweig, Steven; Kline, Jeffrey; Tran, Oth; Smith, David M; Bookhart, Brahim; Crivera, Concetta; Schein, Jeff

    2016-10-06

    % confidence interval, $8035-$8739]; warfarin $10 275 [95% confidence interval, $9842-$10 708]). Rivaroxaban was associated with significantly shorter hospital LOS and lower hospitalization costs compared with warfarin. © 2016 The Authors, Janssen Scientific Affairs, LLC, and Truven Health Analytics. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  14. Pulmonary Embolism Inpatients Treated With Rivaroxaban Had Shorter Hospital Stays and Lower Costs Compared With Warfarin.

    Science.gov (United States)

    Margolis, Jay M; Deitelzweig, Steven; Kline, Jeffrey; Tran, Oth; Smith, David M; Crivera, Concetta; Bookhart, Brahim; Schein, Jeff

    2016-11-01

    Using real-world data, this study compares inpatient length of stay (LOS) and costs for patients with a primary diagnosis of pulmonary embolism (PE) initiating treatment with oral anticoagulation with rivaroxaban versus warfarin. Hospitalizations from MarketScan's Hospital Drug Database were selected from November 1, 2012, through December 31, 2013, for adults with a primary diagnosis of PE initiating treatment with rivaroxaban or warfarin. Warfarin patients were matched 1:1 to rivaroxaban patients using exact and propensity score matching. Hospital LOS, treatment patterns, and hospitalization costs were evaluated. Matched cohorts included 751 rivaroxaban-treated patients and 751 warfarin-treated patients. Adjusted mean LOS was 3.77 days for rivaroxaban patients (95% CI, 3.66-3.87 days) and 5.48 days for warfarin patients (95% CI, 5.33-5.63 days; P < .001). Mean (SD) LOS was shorter for patients taking rivaroxaban whether admission was for provoked PE (rivaroxaban: 5.2 [5.1] days; warfarin: 7.0 [6.5] days; P < .001) or unprovoked PE (rivaroxaban: 3.4 [2.3] days; warfarin: 5.1 [2.7] days; P < .001). Mean (SD) days from first dose to discharge were 2.5 (1.7) (rivaroxaban) and 4.0 (2.9) (warfarin) when initiated with parenteral anticoagulants (P < .001) and 2.7 (1.7) (rivaroxaban) and 4.0 (2.2) (warfarin) without parenteral anticoagulants (P < .001). The rivaroxaban cohort incurred significantly lower unadjusted mean (SD) hospitalization costs (rivaroxaban: $8473 [$9105]; warfarin: $10,291 [$9185]; P < .001), confirmed by covariate adjustment with generalized linear modeling estimating predicted mean hospitalization costs of $8266 for rivaroxaban patients (95% CI, $7851-$8681) and $10,511 for warfarin patients (95% CI, $10,031-$10,992; P < .001). patients with PE treated with rivaroxaban incurred significantly lower hospitalization costs by $2245 per admission compared with patients treated with warfarin, which was attributable to cost offsets from 1.71 fewer days of

  15. The Glycated Albumin (GA) to HbA1c Ratio Reflects Shorter-Term Glycemic Control than GA: Analysis of Patients with Fulminant Type 1 Diabetes.

    Science.gov (United States)

    Koga, Masafumi; Inada, Shinya; Nakao, Taisei; Kawamori, Ryuzo; Kasayama, Soji

    2017-01-01

    Glycated albumin (GA) reflects shorter-term glycemic control than HbA1c. We have reported that HbA1c is paradoxically increased in diabetic patients whose glycemic control deteriorated before ameliorating. In this study, we analyzed paradoxical increases of glycemic control indicators after treatment in patients with fulminant type 1 diabetes (FT1D). We also investigated whether the GA/HbA1c ratio may reflect shorter-term glycemic control than GA. Five FT1D patients whose post-treatment HbA1c and GA levels were measured were enrolled. We also used a formula to estimate HbA1c and GA from the fictitious models of changes in plasma glucose in FT1D patients. In this model, the periods during which HbA1c, GA, and the GA/HbA1c ratio were higher than at the first visit were compared. In addition, the half-life for the GA/HbA1c ratio was calculated in accordance with the half-lives for HbA1c and GA (36 and 14 days, respectively). In all FT1D patients, HbA1c levels 2-4 weeks after treatment were increased, with three patients (60%) experiencing an increase of GA levels. In contrast, an increase of the GA/HbA1c ratio was observed in only one patient. In all of the different models of changes in plasma glucose in FT1D patients, the length of time during which the values were higher than at the first visit was in the order of HbA1c > GA > GA/HbA1c ratio. The half-life for the GA/HbA1c ratio was 9 days, shorter than GA. These findings suggest that the GA/HbA1c ratio reflects shorter-term glycemic control than GA. © 2016 Wiley Periodicals, Inc.

  16. Problem Periods

    Science.gov (United States)

    ... ovary syndrome. Read our information on PCOS for teens , and see your doctor if you think you may have PCOS. Major weight loss. Girls who have anorexia will often stop having periods. When to see ...

  17. Visualization of construction engineering

    International Nuclear Information System (INIS)

    Okada, Hisako; Miura, Jun

    2000-01-01

    It is required for nuclear power plant construction to reduce construction cost and shorten construction period. An early and accurate construction planning including schedule coordination among the companies has recently become more important and it is possible to obtain necessary information for construction planning in early stage. In this situation, we have been developing a visualization system for construction engineering for nuclear power plants. This system has an interface with the existing Plant Layout 3D-CAD system and consists of three sub systems: (1) Scheduling and simulation system, (2) Yard planning system and (3) Scaffolding planning system. This paper describes overview of this system. This visualization system is very helpful for construction engineers to easily understand situation and environment around installation area, to easily plan a work sequence and confirm the planned schedule, and it is also effective for customers and workers to understand the planning. As a result, this visualization system enables safety and high quality construction. (author)

  18. Periods and Nori motives

    CERN Document Server

    Huber, Annette

    2017-01-01

    This book casts the theory of periods of algebraic varieties in the natural setting of Madhav Nori’s abelian category of mixed motives. It develops Nori’s approach to mixed motives from scratch, thereby filling an important gap in the literature, and then explains the connection of mixed motives to periods, including a detailed account of the theory of period numbers in the sense of Kontsevich-Zagier and their structural properties. Period numbers are central to number theory and algebraic geometry, and also play an important role in other fields such as mathematical physics. There are long-standing conjectures about their transcendence properties, best understood in the language of cohomology of algebraic varieties or, more generally, motives. Readers of this book will discover that Nori’s unconditional construction of an abelian category of motives (over fields embeddable into the complex numbers) is particularly well suited for this purpose. Notably, Kontsevich's formal period algebra represents a to...

  19. Nation-Scale Adoption of Shorter Breast Radiation Therapy Schedules Can Increase Survival in Resource Constrained Economies: Results From a Markov Chain Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Khan, Atif J., E-mail: atif.j.khan@rutgers.edu [Department of Radiation Oncology, Robert Wood Johnson Medical School/Cancer Institute of New Jersey, New Brunswick, New Jersey (United States); Rafique, Raza [Suleman Dawood School of Business, Lahore University of Management Sciences, Lahore (Pakistan); Zafar, Waleed [Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore (Pakistan); Shah, Chirag [Department of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio (United States); Haffty, Bruce G. [Department of Radiation Oncology, Robert Wood Johnson Medical School/Cancer Institute of New Jersey, New Brunswick, New Jersey (United States); Vicini, Frank [Michigan HealthCare Professionals, Farmington Hills, Michigan (United States); Jamshed, Arif [Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore (Pakistan); Zhao, Yao [Rutgers University School of Business, Newark, New Jersey (United States)

    2017-02-01

    Purpose: Hypofractionated whole breast irradiation and accelerated partial breast irradiation (APBI) offer women options for shorter courses of breast radiation therapy. The impact of these shorter schedules on the breast cancer populations of emerging economies with limited radiation therapy resources is unknown. We hypothesized that adoption of these schedules would improve throughput in the system and, by allowing more women access to life-saving treatments, improve patient survival within the system. Methods and Materials: We designed a Markov chain model to simulate the different health states that a postlumpectomy or postmastectomy patient could enter over the course of a 20-year follow-up period. Transition rates between health states were adapted from published data on recurrence rates. We used primary data from a tertiary care hospital in Lahore, Pakistan, to populate the model with proportional use of mastectomy versus breast conservation and to estimate the proportion of patients suitable for APBI. Sensitivity analyses on the use of APBI and relative efficacy of APBI were conducted to study the impact on the population. Results: The shorter schedule resulted in more women alive and more women remaining without evidence of disease (NED) compared with the conventional schedule, with an absolute difference of about 4% and 7% at 15 years, respectively. Among women who had lumpectomies, the chance of remaining alive and with an intact breast was 62% in the hypofractionation model and 54% in the conventional fractionation model. Conclusions: Increasing throughput in the system can result in improved survival, improved chances of remaining without evidence of disease, and improved chances of remaining alive with a breast. These findings are significant and suggest that adoption of hypofractionation in emerging economies is not simply a question of efficiency and cost but one of access to care and patient survivorship.

  20. Nation-Scale Adoption of Shorter Breast Radiation Therapy Schedules Can Increase Survival in Resource Constrained Economies: Results From a Markov Chain Analysis

    International Nuclear Information System (INIS)

    Khan, Atif J.; Rafique, Raza; Zafar, Waleed; Shah, Chirag; Haffty, Bruce G.; Vicini, Frank; Jamshed, Arif; Zhao, Yao

    2017-01-01

    Purpose: Hypofractionated whole breast irradiation and accelerated partial breast irradiation (APBI) offer women options for shorter courses of breast radiation therapy. The impact of these shorter schedules on the breast cancer populations of emerging economies with limited radiation therapy resources is unknown. We hypothesized that adoption of these schedules would improve throughput in the system and, by allowing more women access to life-saving treatments, improve patient survival within the system. Methods and Materials: We designed a Markov chain model to simulate the different health states that a postlumpectomy or postmastectomy patient could enter over the course of a 20-year follow-up period. Transition rates between health states were adapted from published data on recurrence rates. We used primary data from a tertiary care hospital in Lahore, Pakistan, to populate the model with proportional use of mastectomy versus breast conservation and to estimate the proportion of patients suitable for APBI. Sensitivity analyses on the use of APBI and relative efficacy of APBI were conducted to study the impact on the population. Results: The shorter schedule resulted in more women alive and more women remaining without evidence of disease (NED) compared with the conventional schedule, with an absolute difference of about 4% and 7% at 15 years, respectively. Among women who had lumpectomies, the chance of remaining alive and with an intact breast was 62% in the hypofractionation model and 54% in the conventional fractionation model. Conclusions: Increasing throughput in the system can result in improved survival, improved chances of remaining without evidence of disease, and improved chances of remaining alive with a breast. These findings are significant and suggest that adoption of hypofractionation in emerging economies is not simply a question of efficiency and cost but one of access to care and patient survivorship.

  1. Investigations of model polymers: Dynamics of melts and statics of a long chain in a dilute melt of shorter chains

    International Nuclear Information System (INIS)

    Bishop, M.; Ceperley, D.; Frisch, H.L.; Kalos, M.H.

    1982-01-01

    We report additional results on a simple model of polymers, namely the diffusion in concentrated polymer systems and the static properties of one long chain in a dilute melt of shorter chains. It is found, for the polymer sizes and time scales amenable to our computer calculations, that there is as yet no evidence for a ''reptation'' regime in a melt. There is some indication of reptation in the case of a single chain moving through fixed obstacles. No statistically significant effect of the change, from excluded volume behavior of the long chain to ideal behavior as the shorter chains grow, is observed

  2. Shorter sleep duration is associated with social impairment and comorbidities in ASD.

    Science.gov (United States)

    Veatch, Olivia J; Sutcliffe, James S; Warren, Zachary E; Keenan, Brendan T; Potter, Melissa H; Malow, Beth A

    2017-07-01

    Sleep disturbance, particularly insomnia, is common in children with autism spectrum disorders (ASD). Furthermore, disturbed sleep affects core symptoms and other related comorbidities. Understanding the causes and consequences of sleep disturbances in children with ASD is an important step toward mitigating these symptoms. To better understand the connection between sleep duration and ASD severity, we analyzed ASD-related symptoms using the Autism Diagnostic Interview-Revised (ADI-R), Autism Diagnostic Observation Schedule (ADOS), IQ scores, and parent reports of the average amount of time slept per night that were available in the medical histories of 2,714 children with ASD in the Simons Simplex Collection (SSC). The mean (SD) sleep duration was 555 minutes. Sleep duration and severity of core ASD symptoms were negatively correlated, and sleep duration and IQ scores were positively correlated. Regression results indicated that more severe social impairment, primarily a failure to develop peer relationships, is the core symptom most strongly associated with short sleep duration. Furthermore, increased severity for numerous maladaptive behaviors assessed on the Child Behavior Checklist, as well as reports of attention deficit disorder, depressive disorder, and obsessive compulsive disorder were associated with short sleep duration. Severity scores for social/communication impairment and restricted and repetitive behaviors (RRB) were increased, and IQ scores were decreased, for children reported to sleep ≤420 minutes per night (lower 5th percentile) compared to children sleeping ≥660 minutes (upper 95th percentile). Our results indicate that reduced amounts of sleep are related to more severe symptoms in children with ASD. Autism Res 2017. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Autism Res 2017, 10: 1221-1238. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. © 2017 International Society for Autism

  3. Constructed Wetlands

    Science.gov (United States)

    these systems can improve water quality, engineers and scientists construct systems that replicate the functions of natural wetlands. Constructed wetlands are treatment systems that use natural processes

  4. Human Resource Construction

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Centering on strategic objective of reform and development,CIAE formulated its objectives in human resource construction for the 13th Five-year Plan period,and achieved new apparent progress in human resource construction in 2015.1 Implementation of"LONGMA Project"

  5. Assessing the reliability and validity of a shorter version of RIASEC in Turkish

    Directory of Open Access Journals (Sweden)

    Süerdem Ahmet

    2016-01-01

    Full Text Available Holland’s RIASEC types are being frequently utilized in commercial vocational profiling tools for various human resources purposes. On the other hand, the length of the RIASEC scale and the copyright restrictions put by the publishers, are important barriers to application. In the present study, a RIASEC scale consisting of 41 items and adapted to Turkish language and culture, was developed. Each RIASEC type was represented with 6 or 7 items. Responses were obtained from a sample of 364 business professionals. Survey results indicated a good reliability for the scale, with a Cronbach’s alpha of 0.889. However, reliability analysis pointed out to the need for revision of certain scale items when each RIASEC facet was separately analysed. Then, feedback regarding scale composition, wording and structure were gathered from 20 PhD students. Lastly, feedback of 7 HR professionals were sought, regarding scale items’ expression and application of the scale in regular HR processes of companies. Results from face and content validity have been that for some items of the scale, more descriptive and specific expressions in Turkish are required. Moreover, some of the items would need to be reallocated to another facet where they would be more relevant. In line with findings from face and content validity, construct validity through confirmatory factor analysis also indicated that the short version of RIASEC must be revised substantially in order to become a valid tool for vocational profiling in Turkish context.

  6. Construction management

    CERN Document Server

    Pellicer, Eugenio; Teixeira, José C; Moura, Helder P; Catalá, Joaquín

    2014-01-01

    The management of construction projects is a wide ranging and challenging discipline in an increasingly international industry, facing continual challenges and demands for improvements in safety, in quality and cost control, and in the avoidance of contractual disputes. Construction Management grew out of a Leonardo da Vinci project to develop a series of Common Learning Outcomes for European Managers in Construction. Financed by the European Union, the project aimed to develop a library of basic materials for developing construction management skills for use in a pan-European context. Focused exclusively on the management of the construction phase of a building project from the contractor's point of view, Construction Management covers the complete range of topics of which mastery is required by the construction management professional for the effective delivery of new construction projects. With the continued internationalisation of the construction industry, Construction Management will be required rea...

  7. A shorter snowfall season associated with higher air temperatures over northern Eurasia

    International Nuclear Information System (INIS)

    Ye Hengchun; Cohen, Judah

    2013-01-01

    The temperature sensitivity of the snowfall season (start, end, duration) over northern Eurasia (the former USSR) is analyzed from synoptic records of 547 stations from 1966 to 2000. The results find significant correlations between temperature and snowfall season at approximately 56% of stations (61% for the starting date and 56% for the ending date) with a mean snowfall season duration temperature sensitivity of −6.2 days °C −1 split over the start (2.8 days) and end periods (−3.4 days). Temperature sensitivity was observed to increase with stations’ mean seasonal air temperature, with the strongest relationships at locations of around 6 °C temperature. This implies that increasing air temperature in fall and spring will delay the onset and hasten the end of snowfall events, and reduces the snowfall season length by 6.2 days for each degree of increase. This study also clarifies that the increasing trend in snowfall season length during 1936/37–1994 over northern European Russia and central Siberia revealed in an earlier study is unlikely to be associated with warming in spring and fall seasons. (letter)

  8. Making tomorrow's mistakes today: Evolutionary prototyping for risk reduction and shorter development time

    Science.gov (United States)

    Friedman, Gary; Schwuttke, Ursula M.; Burliegh, Scott; Chow, Sanguan; Parlier, Randy; Lee, Lorrine; Castro, Henry; Gersbach, Jim

    1993-01-01

    In the early days of JPL's solar system exploration, each spacecraft mission required its own dedicated data system with all software applications written in the mainframe's native assembly language. Although these early telemetry processing systems were a triumph of engineering in their day, since that time the computer industry has advanced to the point where it is now advantageous to replace these systems with more modern technology. The Space Flight Operations Center (SFOC) Prototype group was established in 1985 as a workstation and software laboratory. The charter of the lab was to determine if it was possible to construct a multimission telemetry processing system using commercial, off-the-shelf computers that communicated via networks. The staff of the lab mirrored that of a typical skunk works operation -- a small, multi-disciplinary team with a great deal of autonomy that could get complex tasks done quickly. In an effort to determine which approaches would be useful, the prototype group experimented with all types of operating systems, inter-process communication mechanisms, network protocols, packet size parameters. Out of that pioneering work came the confidence that a multi-mission telemetry processing system could be built using high-level languages running in a heterogeneous, networked workstation environment. Experience revealed that the operating systems on all nodes should be similar (i.e., all VMS or all PC-DOS or all UNIX), and that a unique Data Transport Subsystem tool needed to be built to address the incompatibilities of network standards, byte ordering, and socket buffering. The advantages of building a telemetry processing system based on emerging industry standards were numerous: by employing these standards, we would no longer be locked into a single vendor. When new technology came to market which offered ten times the performance at one eighth the cost, it would be possible to attach the new machine to the network, re-compile the

  9. Making tomorrow's mistakes today: Evolutionary prototyping for risk reduction and shorter development time

    Science.gov (United States)

    Friedman, Gary; Schwuttke, Ursula M.; Burliegh, Scott; Chow, Sanguan; Parlier, Randy; Lee, Lorrine; Castro, Henry; Gersbach, Jim

    1993-03-01

    In the early days of JPL's solar system exploration, each spacecraft mission required its own dedicated data system with all software applications written in the mainframe's native assembly language. Although these early telemetry processing systems were a triumph of engineering in their day, since that time the computer industry has advanced to the point where it is now advantageous to replace these systems with more modern technology. The Space Flight Operations Center (SFOC) Prototype group was established in 1985 as a workstation and software laboratory. The charter of the lab was to determine if it was possible to construct a multimission telemetry processing system using commercial, off-the-shelf computers that communicated via networks. The staff of the lab mirrored that of a typical skunk works operation -- a small, multi-disciplinary team with a great deal of autonomy that could get complex tasks done quickly. In an effort to determine which approaches would be useful, the prototype group experimented with all types of operating systems, inter-process communication mechanisms, network protocols, packet size parameters. Out of that pioneering work came the confidence that a multi-mission telemetry processing system could be built using high-level languages running in a heterogeneous, networked workstation environment. Experience revealed that the operating systems on all nodes should be similar (i.e., all VMS or all PC-DOS or all UNIX), and that a unique Data Transport Subsystem tool needed to be built to address the incompatibilities of network standards, byte ordering, and socket buffering. The advantages of building a telemetry processing system based on emerging industry standards were numerous: by employing these standards, we would no longer be locked into a single vendor. When new technology came to market which offered ten times the performance at one eighth the cost, it would be possible to attach the new machine to the network, re-compile the

  10. Shorter HBIG administration is not associated to HBV recurrence when receiving combined prophylaxis after liver transplantation.

    Science.gov (United States)

    Lens, Sabela; García-Eliz, María; Fernández, Inmaculada; Castells, Lluis; Bonacci, Martin; Mas, Antoni; Crespo, Gonzalo; Buti, María; Prieto, Martín; Forns, Xavier

    2018-04-16

    The combination of hepatitis B immunoglobulin (HBIG) and a nucleos(t)ide analogs (NA) has markedly reduced the rate of hepatitis B (HBV) recurrence after liver transplantation (LT); however, the optimal duration of HBIG has not been clarified. This lack of consensus perpetuates the use of different strategies. The aim of this study was to evaluate the risk factors associated to HBV recurrence after LT in a large cohort of patients under different HBIG regimens. Retrospective multicenter analysis of HBV-related LT recipients receiving combined prophylaxis (HBIG+NA). The strategy of short-term HBIG was compared to life-long administration. HBV recurrence was defined as positive HBsAg after LT. 338 patients were analyzed. After a median follow-up period of 72 months, 37 patients (11%) developed HBV recurrence. Hepatocellular carcinoma (HCC) recurrence and lamivudine resistance after LT were the only factors independently associated to HBV recurrence (HR 5.4[2.3-12] and 9.3[4.2-20], respectively pHBV recurrence was transient (16 patients), persistent (15) or alternant (6). The HBIG regimen did not have an impact on the rate or evolution of HBV recurrence. Overall, patient survival was good and not influenced by HBV recurrence (82% at 5 years). Fulminant liver failure, hepatitis C coinfection or HCC at LT were independent risk factors for lower survival. LT is an effective treatment for HBV-related liver disease. Since the introduction of combined prophylaxis the rate of HBV recurrence is very low. However, life-long HBIG administration does not seem necessary to reduce HBV recurrence. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  11. HITACHI construction CAE system

    International Nuclear Information System (INIS)

    Yoshida, M.

    1994-01-01

    Construction and maintenance of nuclear power plants have important problems such as shortening the construction period and reducing the construction cost. Recently, the problem of insufficient construction labor has arisen, and as drastic strategic development has become a necessary counter-measure. The following four principles are included in the measures to be taken for efficient execution of the construction work within the short construction period: (1) reduction of on-site work and expansion of module block making, (2)improvement of the accuracy of the on-site work process, adjustment and expansion of the work in parallel with the construction process, (3)improvement of efficiency of the on-site work and mechanization and automation of the work, (4)improvement of the accuracy of the management of the construction. A three dimensional simulation system plant construction plan CAE, comprising five modules has been developed. A project management system was also developed to improve the accuracy and efficiency of management work in the field

  12. Moderate Exercise Allows for shorter Recovery Time in Critical Limb Ischemia

    Directory of Open Access Journals (Sweden)

    Anne Lejay

    2017-07-01

    Full Text Available Whether and how moderate exercise might allow for accelerated limb recovery in chronic critical limb ischemia (CLI remains to be determined. Chronic CLI was surgically induced in mice, and the effect of moderate exercise (training five times per week over a 3-week period was investigated. Tissue damages and functional scores were assessed on the 4th, 6th, 10th, 20th, and 30th day after surgery. Mice were sacrificed 48 h after the last exercise session in order to assess muscle structure, mitochondrial respiration, calcium retention capacity, oxidative stress and transcript levels of genes encoding proteins controlling mitochondrial functions (PGC1α, PGC1β, NRF1 and anti-oxidant defenses markers (SOD1, SOD2, catalase. CLI resulted in tissue damages and impaired functional scores. Mitochondrial respiration and calcium retention capacity were decreased in the ischemic limb of the non-exercised group (Vmax = 7.11 ± 1.14 vs. 9.86 ± 0.86 mmol 02/min/g dw, p < 0.001; CRC = 7.01 ± 0.97 vs. 11.96 ± 0.92 microM/mg dw, p < 0.001, respectively. Moderate exercise reduced tissue damages, improved functional scores, and restored mitochondrial respiration and calcium retention capacity in the ischemic limb (Vmax = 9.75 ± 1.00 vs. 9.82 ± 0.68 mmol 02/min/g dw; CRC = 11.36 ± 1.33 vs. 12.01 ± 1.24 microM/mg dw, respectively. Exercise also enhanced the transcript levels of PGC1α, PGC1β, NRF1, as well as SOD1, SOD2, and catalase. Moderate exercise restores mitochondrial respiration and calcium retention capacity, and it has beneficial functional effects in chronic CLI, likely by stimulating reactive oxygen species-induced biogenesis and anti-oxidant defenses. These data support further development of exercise therapy even in advanced peripheral arterial disease.

  13. From Periodic Properties to a Periodic Table Arrangement

    Science.gov (United States)

    Besalú, Emili

    2013-01-01

    A periodic table is constructed from the consideration of periodic properties and the application of the principal components analysis technique. This procedure is useful for objects classification and data reduction and has been used in the field of chemistry for many applications, such as lanthanides, molecules, or conformers classification.…

  14. Electrochemical construction

    Science.gov (United States)

    Einstein, Harry; Grimes, Patrick G.

    1983-08-23

    An electrochemical cell construction features a novel co-extruded plastic electrode in an interleaved construction with a novel integral separator-spacer. Also featured is a leak and impact resistant construction for preventing the spill of corrosive materials in the event of rupture.

  15. Usability Constructs

    DEFF Research Database (Denmark)

    Hertzum, Morten; Clemmesen, Torkil; Hornbæk, Kasper Anders Søren

    2007-01-01

    Whereas research on usability predominantly employs universal definitions of the aspects that comprise usability, people experience their use of information systems through personal constructs. Based on 48 repertory-grid interviews, this study investigates how such personal constructs are affected...... use of constructs traditionally associated with usability (e.g., easy-to-use, intuitive, and liked). Further analysis of the data is ongoing...

  16. Construction mathematics

    CERN Document Server

    Virdi, Surinder; Virdi, Narinder Kaur

    2014-01-01

    Construction Mathematics is an introductory level mathematics text, written specifically for students of construction and related disciplines. Learn by tackling exercises based on real-life construction maths. Examples include: costing calculations, labour costs, cost of materials and setting out of building components. Suitable for beginners and easy to follow throughout. Learn the essential basic theory along with the practical necessities. The second edition of this popular textbook is fully updated to match new curricula, and expanded to include even more learning exercises. End of chapter exercises cover a range of theoretical as well as practical problems commonly found in construction practice, and three detailed assignments based on practical tasks give students the opportunity to apply all the knowledge they have gained. Construction Mathematics addresses all the mathematical requirements of Level 2 construction NVQs from City & Guilds/CITB and Edexcel courses, including the BTEC First Diploma in...

  17. FFTF constructibility

    International Nuclear Information System (INIS)

    Weber, S.A.; Hulbert, D.I.

    1975-01-01

    The influence of the design criteria on the constructibility of the Fast Flux Test Facility is described. Specifically, the effects of requirements due to maintenance accessibility, inerting of cells, seismicity, codes, and standards are addressed. The design and construction techniques developed to minimize the impact of the design criteria on cost and schedule are presented with particular emphasis on the cleanliness and humidity controls imposed during construction of the sodium systems. (U.S.)

  18. Optimization of a shorter variable-acquisition time for legs to achieve true whole-body PET/CT images.

    Science.gov (United States)

    Umeda, Takuro; Miwa, Kenta; Murata, Taisuke; Miyaji, Noriaki; Wagatsuma, Kei; Motegi, Kazuki; Terauchi, Takashi; Koizumi, Mitsuru

    2017-12-01

    The present study aimed to qualitatively and quantitatively evaluate PET images as a function of acquisition time for various leg sizes, and to optimize a shorter variable-acquisition time protocol for legs to achieve better qualitative and quantitative accuracy of true whole-body PET/CT images. The diameters of legs to be modeled as phantoms were defined based on data derived from 53 patients. This study analyzed PET images of a NEMA phantom and three plastic bottle phantoms (diameter, 5.68, 8.54 and 10.7 cm) that simulated the human body and legs, respectively. The phantoms comprised two spheres (diameters, 10 and 17 mm) containing fluorine-18 fluorodeoxyglucose solution with sphere-to-background ratios of 4 at a background radioactivity level of 2.65 kBq/mL. All PET data were reconstructed with acquisition times ranging from 10 to 180, and 1200 s. We visually evaluated image quality and determined the coefficient of variance (CV) of the background, contrast and the quantitative %error of the hot spheres, and then determined two shorter variable-acquisition protocols for legs. Lesion detectability and quantitative accuracy determined based on maximum standardized uptake values (SUV max ) in PET images of a patient using the proposed protocols were also evaluated. A larger phantom and a shorter acquisition time resulted in increased background noise on images and decreased the contrast in hot spheres. A visual score of ≥ 1.5 was obtained when the acquisition time was ≥ 30 s for three leg phantoms, and ≥ 120 s for the NEMA phantom. The quantitative %errors of the 10- and 17-mm spheres in the leg phantoms were ± 15 and ± 10%, respectively, in PET images with a high CV (scan mean SUV max of three lesions using the current fixed-acquisition and two proposed variable-acquisition time protocols in the clinical study were 3.1, 3.1 and 3.2, respectively, which did not significantly differ. Leg acquisition time per bed position of even 30-90

  19. TIA model is attainable in Wistar rats by intraluminal occlusion of the MCA for 10min or shorter.

    Science.gov (United States)

    Durukan Tolvanen, A; Tatlisumak, E; Pedrono, E; Abo-Ramadan, U; Tatlisumak, T

    2017-05-15

    Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the event animals are free from any sensorimotor deficit and from any detectable lesion by magnetic resonance imaging (MRI). Animals experienced varying durations of ischemia (5, 10, 12.5, 15, 25, and 30min, n=6-8pergroup) by intraluminal middle cerebral artery occlusion (MCAO). Ischemia severity and reperfusion rates were controlled by cerebral blood flow measurements. Sensorimotor neurological evaluations and MRI at 24h differentiated between TIA and ischemic stroke. Hematoxylin and eosin staining and apoptotic cell counts revealed pathological correlates of the event. We found that already 12.5min of ischemia was long enough to induce ischemic stroke in Wistar rats. Ten min or shorter durations induced neither gross neurological deficits nor infarcts visible on MRI, but histologically caused selective neuronal necrosis. A separate group of animals with 10min of ischemia followed up to 1week after reperfusion remained free of infarction and any MRI signal change. Thus, 10min or shorter focal cerebral ischemia induced by intraluminal MCAO in Wistar rats provides a clinically relevant TIA the rat. This model is useful for studying molecular correlates of TIA. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Use of a novel shorter minimum caliber needle for creating endoscopic tattoos for preoperative localization: a comparative ex vivo study.

    Science.gov (United States)

    Imai, Kenichiro; Hotta, Kinichi; Ito, Sayo; Yamaguchi, Yuichiro; Kawakami, Takeshi; Wada, Takuya; Igarashi, Kimihiro; Kishida, Yoshihiro; Kinugasa, Yusuke; Kawata, Noboru; Tanaka, Masaki; Kakushima, Naomi; Takizawa, Kohei; Ishiwatari, Hirotoshi; Matsubayashi, Hiroyuki; Ono, Hiroyuki

    2017-06-01

    In colorectal cancer surgery, inadvertent deep injections during endoscopic tattooing can cause India ink leakage into the peritoneum, leading to complications or to poor visualization of the surgical plane. This ex vivo animal study compared the use of novel shorter, minimum caliber needles versus conventional injection needles for endoscopic tattooing. Four endoscopists used the novel needles and conventional needles to make ten endoscopic tattoos (five tattoos/needle type/endoscopist) in harvested porcine rectum using a saline test-injection method. India ink leakage and the success of the tattoo (i. e. visible, tattoos but for none of the novel needle tattoos ( P  = 0.02). Tattoos created using the novel needles were more successful than those made with the conventional needles: 18/20 (90 %) vs. 11/20 (55 %); P  = 0.01. The use of novel shorter minimum caliber needles may be safe and effective for endoscopic tattooing for preoperative localization prior to colorectal cancer surgery.

  1. Construction Management.

    Science.gov (United States)

    Abbott, James F.

    This article provides a detailed discussion of a team approach to building that involves a construction manager, an architect, and a contractor. Bidding methods are outlined; the major components in construction management -- value engineering and fast track scheduling -- and the use of performance specifications are discussed. The construction…

  2. Construction fraud

    NARCIS (Netherlands)

    Graafland, J.J.; Liedekerke, L.; Dubbink, W.; van Liedekerke, L.; van Luijk, H.

    2011-01-01

    Due to the actions of a whistleblower The Netherlands was confronted with a massive case of construction fraud involving almost the entire construction sector. Price fixing, prior consulting, duplicate accounts, fictitious invoices and active corruption of civil servants were rampant practices. This

  3. Superstring construction

    CERN Document Server

    1989-01-01

    The book includes a selection of papers on the construction of superstring theories, mainly written during the years 1984-1987. It covers ten-dimensional supersymmetric and non-supersymmetric strings, four-dimensional heterotic strings and four-dimensional type-II strings. An introduction to more recent developments in conformal field theory in relation to string construction is provided.

  4. Holonomic systems for period mappings

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Jingyue, E-mail: jychen@brandeis.edu [Department of Mathematics, Brandeis University, Waltham, MA 02454 (United States); Huang, An, E-mail: anhuang@math.harvard.edu [Department of Mathematics, Harvard University, Cambridge, MA 02138 (United States); Lian, Bong H., E-mail: lian@brandeis.edu [Department of Mathematics, Brandeis University, Waltham, MA 02454 (United States)

    2015-09-15

    Period mappings were introduced in the sixties [4] to study variation of complex structures of families of algebraic varieties. The theory of tautological systems was introduced recently [7,8] to understand period integrals of algebraic manifolds. In this paper, we give an explicit construction of a tautological system for each component of a period mapping. We also show that the D-module associated with the tautological system gives rise to many interesting vanishing conditions for period integrals at certain special points of the parameter space.

  5. At least 10% shorter C–H bonds in cryogenic protein crystal structures than in current AMBER forcefields

    Energy Technology Data Exchange (ETDEWEB)

    Pang, Yuan-Ping, E-mail: pang@mayo.edu

    2015-03-06

    High resolution protein crystal structures resolved with X-ray diffraction data at cryogenic temperature are commonly used as experimental data to refine forcefields and evaluate protein folding simulations. However, it has been unclear hitherto whether the C–H bond lengths in cryogenic protein structures are significantly different from those defined in forcefields to affect protein folding simulations. This article reports the finding that the C–H bonds in high resolution cryogenic protein structures are 10–14% shorter than those defined in current AMBER forcefields, according to 3709 C–H bonds in the cryogenic protein structures with resolutions of 0.62–0.79 Å. Also, 20 all-atom, isothermal–isobaric, 0.5-μs molecular dynamics simulations showed that chignolin folded from a fully-extended backbone formation to the native β-hairpin conformation in the simulations using AMBER forcefield FF12SB at 300 K with an aggregated native state population including standard error of 10 ± 4%. However, the aggregated native state population with standard error reduced to 3 ± 2% in the same simulations except that C–H bonds were shortened by 10–14%. Furthermore, the aggregated native state populations with standard errors increased to 35 ± 3% and 26 ± 3% when using FF12MC, which is based on AMBER forcefield FF99, with and without the shortened C–H bonds, respectively. These results show that the 10–14% bond length differences can significantly affect protein folding simulations and suggest that re-parameterization of C–H bonds according to the cryogenic structures could improve the ability of a forcefield to fold proteins in molecular dynamics simulations. - Highlights: • Cryogenic crystal structures are commonly used in computational studies of proteins. • C–H bonds in the cryogenic structures are shorter than those defined in forcefields. • A survey of 3709 C–H bonds shows that the cryogenic bonds are 10–14% shorter. • The

  6. Shorter telomeres in peripheral blood mononuclear cells from older persons with sarcopenia: results from an exploratory study

    Directory of Open Access Journals (Sweden)

    Emanuele eMarzetti

    2014-08-01

    Full Text Available Background. Telomere shortening in peripheral blood mononuclear cells (PBMCs has been associated with biological age and several chronic degenerative diseases. However, the relationship between telomere length and sarcopenia, a hallmark of the aging process, is unknown. The aim of the present study was therefore to determine whether PBMC telomeres obtained from sarcopenic older persons were shorter relative to non-sarcopenic peers. We further explored if PBMC telomere length was associated with frailty, a major clinical correlate of sarcopenia.Methods. Analyses were conducted in 142 persons aged >/= 65 years referred to a geriatric outpatient clinic (University Hospital. The presence of sarcopenia was established according to the European Working Group on Sarcopenia in Older People criteria, with bioelectrical impedance analysis used for muscle mass estimation. The frailty status was determined by both the Fried’s criteria (physical frailty, PF and a modified Rockwood’s frailty index (FI. Telomere length was measured in PBMCs by quantitative real-time polymerase chain reaction according to the Telomere/Single copy gene ratio (T/S method.Results. Among 142 outpatients (mean age 75.0 ± 6.5 years, 59.2% women, sarcopenia was diagnosed in 23 individuals (19.3%. The PF phenotype was detected in 74 participants (52.1%. The average FI score was 0.46 ± 0.17. PBMC telomeres were shorter in sarcopenic subjects (T/S = 0.21; 95% CI: 0.18 – 0.24 relative to non-sarcopenic individuals (T/S = 0.26; 95%: CI: 0.24 – 0.28; p = 0.01, independent of age, gender, smoking habit, or comorbidity. No significant associations were determined between telomere length and either PF or FI.Conclusion. PBMC telomere length, expressed as T/S values, is shorter in older outpatients with sarcopenia. The cross-sectional assessment of PBMC telomere length is not sufficient at capturing the complex, multidimensional syndrome of frailty.

  7. The aeration period of a model nuclear waste repository

    International Nuclear Information System (INIS)

    Sharland, S.M.; Tasker, P.W.

    1987-02-01

    We have constructed a model of the evolution of oxygen in a cement backfill which includes both its depletion through the canister corrosion reactions and its migration in the cement pores. The results indicate that the duration in which mild steel waste canisters may be subject to localised corrosion is very much shorter than the intended lifetime of the repository components, provided there is no external source of oxygen. For canisters spaced 1.2m apart, the model predicts a maximum aeration period of approximately 65 years, assuming high oxygen content and diffusivity in the backfill and low leakage current on the canisters (0.01 μA cm -2 ). In such a case a reducing environment is established throughout the backfill within this period. Under conditions of more restricted oxygen transport, reducing conditions are still established within a relatively short time in the immediate vicinity of the canisters, but the oxidation potential elsewhere in the backfill is then controlled by the uniform corrosion rate of the canisters. (author)

  8. A Kinetic Model Explains Why Shorter and Less Affine Enzyme-recruiting Oligonucleotides Can Be More Potent

    Directory of Open Access Journals (Sweden)

    Lykke Pedersen

    2014-01-01

    Full Text Available Antisense oligonucleotides complementary to RNA targets promise generality and ease of drug design. The first systemically administered antisense drug was recently approved for treatment and others are in clinical development. Chemical modifications that increase the hybridization affinity of oligonucleotides are reasoned to confer higher potency, i.e., modified oligonucleotides can be dosed at lower concentrations to achieve the same effect. Surprisingly, shorter and less affine oligonucleotides sometimes display increased potency. To explain this apparent contradiction, increased uptake or decreased propensity to form structures have been suggested as possible mechanisms. Here, we provide an alternative explanation that invokes only the kinetics behind oligonucleotide-mediated cleavage of RNA targets. A model based on the law of mass action predicts, and experiments support, the existence of an optimal binding affinity. Exaggerated affinity, and not length per se, is detrimental to potency. This finding clarifies how to optimally apply high-affinity modifications in the discovery of potent antisense oligonucleotide drugs.

  9. Worldwide construction

    International Nuclear Information System (INIS)

    Williamson, M.

    1994-01-01

    The paper lists major construction projects in worldwide processing and pipelining, showing capacities, contractors, estimated costs, and time of construction. The lists are divided into refineries, petrochemical plants, sulfur recovery units, gas processing plants, pipelines, and related fuel facilities. This last classification includes cogeneration plants, coal liquefaction and gasification plants, biomass power plants, geothermal power plants, integrated coal gasification combined-cycle power plants, and a coal briquetting plant

  10. Spindle assembly checkpoint protein expression correlates with cellular proliferation and shorter time to recurrence in ovarian cancer.

    LENUS (Irish Health Repository)

    McGrogan, Barbara

    2014-07-01

    Ovarian carcinoma (OC) is the most lethal of the gynecological malignancies, often presenting at an advanced stage. Treatment is hampered by high levels of drug resistance. The taxanes are microtubule stabilizing agents, used as first-line agents in the treatment of OC that exert their apoptotic effects through the spindle assembly checkpoint. BUB1-related protein kinase (BUBR1) and mitotic arrest deficient 2 (MAD2), essential spindle assembly checkpoint components, play a key role in response to taxanes. BUBR1, MAD2, and Ki-67 were assessed on an OC tissue microarray platform representing 72 OC tumors of varying histologic subtypes. Sixty-one of these patients received paclitaxel and platinum agents combined; 11 received platinum alone. Overall survival was available for all 72 patients, whereas recurrence-free survival (RFS) was available for 66 patients. Increased BUBR1 expression was seen in serous carcinomas, compared with other histologies (P = .03). Increased BUBR1 was significantly associated with tumors of advanced stage (P = .05). Increased MAD2 and BUBR1 expression also correlated with increased cellular proliferation (P < .0002 and P = .02, respectively). Reduced MAD2 nuclear intensity was associated with a shorter RFS (P = .03), in ovarian tumors of differing histologic subtype (n = 66). In this subgroup, for those women who received paclitaxel and platinum agents combined (n = 57), reduced MAD2 intensity also identified women with a shorter RFS (P < .007). For the entire cohort of patients, irrespective of histologic subtype or treatment, MAD2 nuclear intensity retained independent significance in a multivariate model, with tumors showing reduced nuclear MAD2 intensity identifying patients with a poorer RFS (P = .05).

  11. The association between post-traumatic stress disorder and shorter telomere length: A systematic review and meta-analysis.

    Science.gov (United States)

    Li, Xuemei; Wang, Jiang; Zhou, Jianghua; Huang, Pan; Li, Jiping

    2017-08-15

    Post-traumatic stress disorder (PTSD) is a common psychiatric disorder, which may accelerate aging. Many study have investigated the association between telomeres length and PTSD, but results from published studies are contradictory. Therefore, Meta-analysis approaches were conducted to give more precise estimate of relationship between telomere length and PTSD. We systematically reviewed the databases of PUBMED, PsycINFO, Medline(Ovid SP) and EMBASE for all articles on the association between telomere length and PTSD. Data were summarized by using random-effects in the meta-analysis. The heterogeneity among studies were examined by using Cochrane's Q statistic and I-squared. Five eligible studies containing 3851 participants were included in our meta-analysis. Shorten telomere length was significantly associated with PTSD with mean difference of -0.19( 95% CI: -0.27, -0.01; P<0.001) with I-square of 96%. The results from subgroup analysis demonstrated that shorter telomere length was significantly associated with PTSD across all gender groups, with mean difference of -0.15( 95% CI: -0.29, -0.01; P=0.04) for female, mean difference of -0.17( 95% CI: -0.19, -0.15; P<0.001) for male. Meanwhile, shorten telomere length was significantly associated with sexual assault(mean difference =-0.15, 95% CI: -0.29, -0.01), childhood trauma (mean difference =-0.08, 95% CI: -0.19, -0.07), but not combat (mean difference =-0.39, 95% CI: -0.83, 0.05). Compared to the individuals without PTSD, individuals with PTSD have shorter telomere length, which has implications for early intervention and timely treatment to prevent future adverse health outcomes. Copyright © 2017. Published by Elsevier B.V.

  12. Construction history and construction management

    International Nuclear Information System (INIS)

    Agh, S.

    1999-01-01

    The process of pre-design and design preparation of the Mochovce NPP as well as the construction history of the plant is highlighted, including the financing aspect and problems arising from changes in the technological and other conditions of start-up of the reactor units. The results of international audits performed to improve the level of nuclear safety and implementation of the measures suggested are also described. The milestones of the whole construction process and start-up process, the control and quality system, and the methods of control and management of the complex construction project are outlined. (author)

  13. Construction safety

    CERN Document Server

    Li, Rita Yi Man

    2013-01-01

    A close-to-ideal blend of suburb and city, speedy construction of towers of Babylon, the sparkling proportion of glass and steel buildings’ facade at night showcase the wisdom of humans. They also witness the footsteps, sweats and tears of architects and engineers. Unfortunately, these signatures of human civilizations are swathed in towering figures of construction accidents. Fretting about these on sites, different countries adopt different measures on sites. This book firstly sketches the construction accidents on sites, followed by a review on safety measures in some of the developing countries such as Bermuda, Egypt, Kuwait and China; as well as developed countries, for example, the United States, France and Singapore. It also highlights the enormous compensation costs with the courts’ experiences in the United Kingdom and Hong Kong.

  14. Constructing sanctions

    DEFF Research Database (Denmark)

    Jaeger, Mark Daniel

    2016-01-01

    such an effect. This paper explores sanctions conflicts as social constructs. It purports that rally-around-the-flag is all but one part of the discursive dimension of sanctions conflicts. Sanctions are intricately connected with the conflict setting they occur in. The study suggests a dialectical relation...... between how opponents perceive conflicts and the meaning of sanctions therein. This nexus of different constructions of sanctions moreover extends to “targeted” sanctions as well: As restrictive measures against Zimbabwe demonstrate, they are not the kind of minimally-invasive operations with clinical...

  15. The Change of the Family Life Affected by the Shorter Working Time : From the Point of View of the Home Management

    OpenAIRE

    平田, 道憲

    1994-01-01

    In Japan, the working time has been decreasing. However, Japanese working people spend more hours per year to work than those in Western countries. The policy of the shorter working time is conducted by the Japanese Government in order that the working people get more free time. This paper examines whether the shorter working time of working members in the family enrich the time use of the other members of the family. Especially, the effect of the shorter working time of husbands to wives...

  16. Construction work

    CERN Multimedia

    2004-01-01

    Construction work on building 179 will start on the 16th February 2004 and continue until November 2004. The road between buildings 179 and 158 will temporarily become a one way street from Route Democrite towards building 7. The parking places between buildings 179 and 7 will become obsolete. The ISOLDE collaboration would like to apologize for any inconveniences.

  17. Elevated CD147 expression is associated with shorter overall survival in non-small cell lung cancer.

    Science.gov (United States)

    Zhang, Xiaojun; Tian, Tian; Zhang, Xiaofeng; Liu, Changting; Fang, Xiangqun

    2017-06-06

    A number of studies have reported on the prognostic role of CD147 expression in non-small cell lung cancer (NSCLC); however, the results remain controversial. This study aims to investigate the impact of CD147 on the prognosis of NSCLC by means of a meta-analysis. A literature search was performed for relevant studies published before October 29, 2016. The hazard ratios (HRs), odds ratios (ORs), and 95% confidence intervals (CIs) were calculated as effective measures. Sensitivity analysis and publication bias examination were also conducted. Ten eligible studies with a total of 1605 patients were included in this meta-analysis. CD147 overexpression was correlated with poor overall survival (OS) (HR=1.59, 95% CI=1.32-1.91, pCD147 expression was associated with the presence of lymph node metastasis (OR=2.31, 95% CI=1.74-3.07, pCD147 and sex, age, differentiation, or histology was found. No evidence of significant publication bias was identified. This meta-analysis revealed that overexpression of CD147 was associated with shorter OS, the presence of lymph node metastasis and advanced TNM stage in NSCLC. Therefore, CD147 could serve as a potential prognostic marker for NSCLC.

  18. Access to Electric Light Is Associated with Shorter Sleep Duration in a Traditionally Hunter-Gatherer Community.

    Science.gov (United States)

    de la Iglesia, Horacio O; Fernández-Duque, Eduardo; Golombek, Diego A; Lanza, Norberto; Duffy, Jeanne F; Czeisler, Charles A; Valeggia, Claudia R

    2015-08-01

    Access to electric light might have shifted the ancestral timing and duration of human sleep. To test this hypothesis, we studied two communities of the historically hunter-gatherer indigenous Toba/Qom in the Argentinean Chaco. These communities share the same ethnic and sociocultural background, but one has free access to electricity while the other relies exclusively on natural light. We fitted participants in each community with wrist activity data loggers to assess their sleep-wake cycles during one week in the summer and one week in the winter. During the summer, participants with access to electricity had a tendency to a shorter daily sleep bout (43 ± 21 min) than those living under natural light conditions. This difference was due to a later daily bedtime and sleep onset in the community with electricity, but a similar sleep offset and rise time in both communities. In the winter, participants without access to electricity slept longer (56 ± 17 min) than those with access to electricity, and this was also related to earlier bedtimes and sleep onsets than participants in the community with electricity. In both communities, daily sleep duration was longer during the winter than during the summer. Our field study supports the notion that access to inexpensive sources of artificial light and the ability to create artificially lit environments must have been key factors in reducing sleep in industrialized human societies. © 2015 The Author(s).

  19. Dyslexics' faster decay of implicit memory for sounds and words is manifested in their shorter neural adaptation.

    Science.gov (United States)

    Jaffe-Dax, Sagi; Frenkel, Or; Ahissar, Merav

    2017-01-24

    Dyslexia is a prevalent reading disability whose underlying mechanisms are still disputed. We studied the neural mechanisms underlying dyslexia using a simple frequency-discrimination task. Though participants were asked to compare the two tones in each trial, implicit memory of previous trials affected their responses. We hypothesized that implicit memory decays faster among dyslexics. We tested this by increasing the temporal intervals between consecutive trials, and by measuring the behavioral impact and ERP responses from the auditory cortex. Dyslexics showed a faster decay of implicit memory effects on both measures, with similar time constants. Finally, faster decay of implicit memory also characterized the impact of sound regularities in benefitting dyslexics' oral reading rate. Their benefit decreased faster as a function of the time interval from the previous reading of the same non-word. We propose that dyslexics' shorter neural adaptation paradoxically accounts for their longer reading times, since it reduces their temporal window of integration of past stimuli, resulting in noisier and less reliable predictions for both simple and complex stimuli. Less reliable predictions limit their acquisition of reading expertise.

  20. Shorter duration of non-rapid eye movement sleep slow waves in EphA4 knockout mice.

    Science.gov (United States)

    Freyburger, Marlène; Poirier, Gaétan; Carrier, Julie; Mongrain, Valérie

    2017-10-01

    Slow waves occurring during non-rapid eye movement sleep have been associated with neurobehavioural performance and memory. In addition, the duration of previous wakefulness and sleep impacts characteristics of these slow waves. However, molecular mechanisms regulating the dynamics of slow-wave characteristics remain poorly understood. The EphA4 receptor regulates glutamatergic transmission and synaptic plasticity, which have both been linked to sleep slow waves. To investigate if EphA4 regulates slow-wave characteristics during non-rapid eye movement sleep, we compared individual parameters of slow waves between EphA4 knockout mice and wild-type littermates under baseline conditions and after a 6-h sleep deprivation. We observed that, compared with wild-type mice, knockout mice display a shorter duration of positive and negative phases of slow waves under baseline conditions and after sleep deprivation. However, the mutation did not change slow-wave density, amplitude and slope, and did not affect the sleep deprivation-dependent changes in slow-wave characteristics, suggesting that EphA4 is not involved in the response to elevated sleep pressure. Our present findings suggest a role for EphA4 in shaping cortical oscillations during sleep that is independent from sleep need. © 2017 European Sleep Research Society.

  1. Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer's disease and progressive supranuclear palsy brains.

    Science.gov (United States)

    Huin, Vincent; Buée, Luc; Behal, Hélène; Labreuche, Julien; Sablonnière, Bernard; Dhaenens, Claire-Marie

    2017-10-03

    Alternative promoter usage is an important mechanism for transcriptome diversity and the regulation of gene expression. Indeed, this alternative usage may influence tissue/subcellular specificity, protein translation and function of the proteins. The existence of an alternative promoter for MAPT gene was considered for a long time to explain differential tissue specificity and differential response to transcription and growth factors between mRNA transcripts. The alternative promoter usage could explain partly the different tau proteins expression patterns observed in tauopathies. Here, we report on our discovery of a functional alternative promoter for MAPT, located upstream of the gene's second exon (exon 1). By analyzing genome databases and brain tissue from control individuals and patients with Alzheimer's disease or progressive supranuclear palsy, we identified novel shorter transcripts derived from this alternative promoter. These transcripts are increased in patients' brain tissue as assessed by 5'RACE-PCR and qPCR. We suggest that these new MAPT isoforms can be translated into normal or amino-terminal-truncated tau proteins. We further suggest that activation of MAPT's alternative promoter under pathological conditions leads to the production of truncated proteins, changes in protein localization and function, and thus neurodegeneration.

  2. Cleavage of SNAP25 and its shorter versions by the protease domain of serotype A botulinum neurotoxin.

    Directory of Open Access Journals (Sweden)

    Rahman M Mizanur

    Full Text Available Various substrates, catalysts, and assay methods are currently used to screen inhibitors for their effect on the proteolytic activity of botulinum neurotoxin. As a result, significant variation exists in the reported results. Recently, we found that one source of variation was the use of various catalysts, and have therefore evaluated its three forms. In this paper, we characterize three substrates under near uniform reaction conditions using the most active catalytic form of the toxin. Bovine serum albumin at varying optimum concentrations stimulated enzymatic activity with all three substrates. Sodium chloride had a stimulating effect on the full length synaptosomal-associated protein of 25 kDa (SNAP25 and its 66-mer substrates but had an inhibitory effect on the 17-mer substrate. We found that under optimum conditions, full length SNAP25 was a better substrate than its shorter 66-mer or 17-mer forms both in terms of kcat, Km, and catalytic efficiency kcat/Km. Assay times greater than 15 min introduced large variations and significantly reduced the catalytic efficiency. In addition to characterizing the three substrates, our results identify potential sources of variations in previous published results, and underscore the importance of using well-defined reaction components and assay conditions.

  3. Shorter time since inflammatory bowel disease diagnosis in children is associated with lower mental health in parents.

    Science.gov (United States)

    Werner, H; Braegger, Cp; Buehr, P; Koller, R; Nydegger, A; Spalinger, J; Heyland, K; Schibli, S; Landolt, Ma

    2015-01-01

    This study assessed the mental health of parents of children with inflammatory bowel disease (IBD), compared their mental health with age-matched and gender-matched references and examined parental and child predictors for mental health problems. A total of 125 mothers and 106 fathers of 125 children with active and inactive IBD from the Swiss IBD multicentre cohort study were included. Parental mental health was assessed by the Symptom Checklist 27 and child behaviour problems by the Strengths and Difficulties Questionnaire. Child medical data were extracted from hospital records. While the mothers reported lower mental health, the fathers' mental health was similar, or even better, than in age-matched and gender-matched community controls. In both parents, shorter time since the child's diagnosis was associated with poorer mental health. In addition, the presence of their own IBD diagnosis and child behaviour problems predicted maternal mental health problems. Parents of children with IBD may need professional support when their child is diagnosed, to mitigate distress. This, in turn, may help the child to adjust better to IBD. Particular attention should be paid to mothers who have their own IBD diagnosis and whose children display behaviour problems. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  4. Shorter Versus Longer Shift Durations to Mitigate Fatigue and Fatigue-Related Risks in Emergency Medical Services Personnel and Related Shift Workers: A Systematic Review

    Science.gov (United States)

    2018-01-11

    Background: This study comprehensively reviewed the literature on the impact of shorter versus longer shifts on critical and important outcomes for Emergency Medical Services (EMS) personnel and related shift worker groups. Methods: Six databases (e....

  5. SHORTER, Aylward. African recruits and missionary conscripts: the White Fathers and the Great War (1914 – 1922. London: Missionaries of Africa History Project, 2007. 270 p. ISBN: 9780955523502

    Directory of Open Access Journals (Sweden)

    Jefferson Olivatto da Silva

    2011-09-01

    Full Text Available Resenha do livroSHORTER, Aylward. African recruits and missionary conscripts: the White Fathers and the Great War (1914 – 1922. London: Missionaries of Africa History Project, 2007. 270 p. ISBN: 9780955523502

  6. Modelling Constructs

    DEFF Research Database (Denmark)

    Kindler, Ekkart

    2009-01-01

    , these notations have been extended in order to increase expressiveness and to be more competitive. This resulted in an increasing number of notations and formalisms for modelling business processes and in an increase of the different modelling constructs provided by modelling notations, which makes it difficult......There are many different notations and formalisms for modelling business processes and workflows. These notations and formalisms have been introduced with different purposes and objectives. Later, influenced by other notations, comparisons with other tools, or by standardization efforts...... to compare modelling notations and to make transformations between them. One of the reasons is that, in each notation, the new concepts are introduced in a different way by extending the already existing constructs. In this chapter, we go the opposite direction: We show that it is possible to add most...

  7. TOPS On-Line: Automating the Construction and Maintenance of HTML Pages

    Science.gov (United States)

    Jones, Kennie H.

    1994-01-01

    After the Technology Opportunities Showcase (TOPS), in October, 1993, Langley Research Center's (LaRC) Information Systems Division (ISD) accepted the challenge to preserve the investment in information assembled in the TOPS exhibits by establishing a data base. Following the lead of several people at LaRC and others around the world, the HyperText Transport Protocol (HTTP) server and Mosaic were the obvious tools of choice for implementation. Initially, some TOPS exhibitors began the conventional approach of constructing HyperText Markup Language (HTML) pages of their exhibits as input to Mosaic. Considering the number of pages to construct, a better approach was conceived that would automate the construction of pages. This approach allowed completion of the data base construction in a shorter period of time using fewer resources than would have been possible with the conventional approach. It also provided flexibility for the maintenance and enhancement of the data base. Since that time, this approach has been used to automate construction of other HTML data bases. Through these experiences, it is concluded that the most effective use of the HTTP/Mosaic technology will require better tools and techniques for creating, maintaining and managing the HTML pages. The development and use of these tools and techniques are the subject of this document.

  8. APPLIED ORGANIZATION OF CONSTRUCTION

    Directory of Open Access Journals (Sweden)

    Kievskiy Leonid Vladimirovich

    2017-03-01

    Full Text Available Applied disciplines in the sphere of construction which are engaged in the solution of vital macroeconomical problems (the general trend of development of these disciplines is the expansion of problematics and mutual integration are considered. Construction organization characteristic at the present stage as a systems engineering discipline covering the investment process of creation of real estate items, is given. The main source of current research trends for applied sciences (socio-economic development forecasts, regional and local programs is determined. Interpenetration and integration of various fields of knowledge exemplified by the current interindustry problem of blocks renovation organization of existing development, is demonstrated. Mathematical model of wave construction (for the period of deployment is proposed. Nature of dependence of the total duration of renovation on the limit of annual input and coefficient of renovation, is established. Overall structure of the Moscow region housing market is presented, and approaches to definition of effective demand are proposed.

  9. The return trip is felt shorter only postdictively: A psychophysiological study of the return trip effect [corrected].

    Directory of Open Access Journals (Sweden)

    Ryosuke Ozawa

    Full Text Available The return trip often seems shorter than the outward trip even when the distance and actual time are identical. To date, studies on the return trip effect have failed to confirm its existence in a situation that is ecologically valid in terms of environment and duration. In addition, physiological influences as part of fundamental timing mechanisms in daily activities have not been investigated in the time perception literature. The present study compared round-trip and non-round-trip conditions in an ecological situation. Time estimation in real time and postdictive estimation were used to clarify the situations where the return trip effect occurs. Autonomic nervous system activity was evaluated from the electrocardiogram using the Lorenz plot to demonstrate the relationship between time perception and physiological indices. The results suggest that the return trip effect is caused only postdictively. Electrocardiographic analysis revealed that the two experimental conditions induced different responses in the autonomic nervous system, particularly in sympathetic nervous function, and that parasympathetic function correlated with postdictive timing. To account for the main findings, the discrepancy between the two time estimates is discussed in the light of timing strategies, i.e., prospective and retrospective timing, which reflect different emphasis on attention and memory processes. Also each timing method, i.e., the verbal estimation, production or comparative judgment, has different characteristics such as the quantification of duration in time units or knowledge of the target duration, which may be responsible for the discrepancy. The relationship between postdictive time estimation and the parasympathetic nervous system is also discussed.

  10. Psoralen-mediated virus photoinactivation in platelet concentrates: enhanced specificity of virus kill in the absence of shorter UVA wavelengths

    International Nuclear Information System (INIS)

    Margolis-Nunno, Henrietta; Robinson, Richard; Horowitz, Bernard; Ben-Hur, Ehud; Geacintov, N.E.

    1995-01-01

    Treatments with psoralens and long-wavelength ultraviolet radiation (UVA, 320-400 nm; PUVA) have shown efficacy for virus sterilization of platelet concentrates (PC). We have employed the psoralen derivative 4'-aminomethyl-4,5',8-trimethylpsoralen (AMT), and have found that platelet integrity is best preserved when rutin, a flavonoid that quenches multiple reactive oxygen species, is present during AMT/UVA treatment of PC. In this report, we examine the effects of different UVA spectra under our standard PC treatment conditions (i.e. 50 μg/mL AMT, 0.35 mM rutin and 38 J/cm 2 UVA). Added vesicular stomatitis virus (VSV; ≥ 5.5 log 10 ) was completely inactivated with the simultaneous maintenance of the platelet aggregation response (> 90% of control) when a UVA light source with transmission mainly between 360 and 370 nm (narrow UVA1) was used. In contrast, with a broad-band UVA (320-400 nm; broad UVA) light source, the aggregation response was greatly compromised (< 50% of control) with only a minor increase in the rate of VSV kill. With this lamp, platelet function could be improved to about 75% of the control by adding a long-pass filter, which reduced the transmission of shorter (≤ 345 nm) UVA wavelengths (340-400 nm; UVA1). At equivalent levels of virus kill, aggregation function was always best preserved when narrow UVA1 was used for PUVA treatment. Even in the absence of AMT, and with or without rutin present, narrow UVA1 irradiation was better tolerated by platelets than was broad UVA. (author)

  11. Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones.

    Directory of Open Access Journals (Sweden)

    Kenta Saito

    Full Text Available TNFα-converting enzyme (TACE is a membrane-bound proteolytic enzyme with essential roles in the functional regulation of TNFα and epidermal growth factor receptor (EGFR ligands. Previous studies have demonstrated critical roles for TACE in vivo, including epidermal development, immune response, and pathological neoangiogenesis, among others. However, the potential contribution of TACE to skeletal development is still unclear. In the present study, we generated a Tace mutant mouse in which Tace is conditionally disrupted in chondrocytes under the control of the Col2a1 promoter. These mutant mice were fertile and viable but all exhibited long bones that were approximately 10% shorter compared to those of wild-type animals. Histological analyses revealed that Tace mutant mice exhibited a longer hypertrophic zone in the growth plate, and there were fewer osteoclasts at the chondro-osseous junction in the Tace mutant mice than in their wild-type littermates. Of note, we found an increase in osteoprotegerin transcripts and a reduction in Rankl and Mmp-13 transcripts in the TACE-deficient cartilage, indicating that dysregulation of these genes is causally related to the skeletal defects in the Tace mutant mice. Furthermore, we also found that phosphorylation of EGFR was significantly reduced in the cartilage tissue lacking TACE, and that suppression of EGFR signaling increases osteoprotegerin transcripts and reduces Rankl and Mmp-13 transcripts in primary chondrocytes. In accordance, chondrocyte-specific abrogation of Egfr in vivo resulted in skeletal defects nearly identical to those observed in the Tace mutant mice. Taken together, these data suggest that TACE-EGFR signaling in chondrocytes is involved in the turnover of the growth plate during postnatal development via the transcriptional regulation of osteoprotegerin, Rankl, and Mmp-13.

  12. Pairs of dual periodic frames

    DEFF Research Database (Denmark)

    Christensen, Ole; Goh, Say Song

    2012-01-01

    The time–frequency analysis of a signal is often performed via a series expansion arising from well-localized building blocks. Typically, the building blocks are based on frames having either Gabor or wavelet structure. In order to calculate the coefficients in the series expansion, a dual frame...... is needed. The purpose of the present paper is to provide constructions of dual pairs of frames in the setting of the Hilbert space of periodic functions L2(0,2π). The frames constructed are given explicitly as trigonometric polynomials, which allows for an efficient calculation of the coefficients...

  13. Construct ability Improvement for Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dae Soo; Lee, Jong Rim; Kim, Jong Ku [Korea Electric Power Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    The purpose of this study was to identify methods for improving the construct ability of nuclear power plants. This study reviewed several references of current construction practices of domestic and overseas nuclear plants in order to identify potential methods for improving construct ability. The identified methods for improving construct ability were then evaluated based on the applicability to domestic nuclear plant construction. The selected methods are expected to reduce the construction period, improve the quality of construction, cost, safety, and productivity. Selection of which methods should be implemented will require further evaluation of construction modifications, design changes, contract revisions. Among construction methods studied, platform construction methods can be applied through construction sequence modification without significant design changes, and Over the Top construction method of the NSSS, automatic welding of RCL pipes, CLP modularization, etc., are considered to be applied after design modification and adjustment of material lead time. (author). 49 refs., figs., tabs.

  14. Sex and ancestry determine the free-running circadian period.

    Science.gov (United States)

    Eastman, Charmane I; Tomaka, Victoria A; Crowley, Stephanie J

    2017-10-01

    The endogenous, free-running circadian period (τ) determines the phase relationship that an organism assumes when entrained to the 24-h day. We found a shorter circadian period in African Americans compared to non-Hispanic European Americans (24.07 versus 24.33 h). We speculate that a short circadian period, closer to 24 h, was advantageous to humans living around the equator, but when humans migrated North out of Africa, where the photoperiod changes with seasons, natural selection favoured people with longer circadian periods. Recently, in evolutionary terms, immigrants came from Europe and Africa to America ('the New World'). The Europeans were descendents of people who had lived in Europe for thousands of years with changing photoperiods (and presumably longer periods), whereas Africans had ancestors who had always lived around the equator (with shorter periods). It may have been advantageous to have a longer circadian period while living in Europe early in the evolution of humans. In our modern world, however, it is better to have a shorter period, because it helps make our circadian rhythms earlier, which is adaptive in our early-bird-dominated society. European American women had a shorter circadian period than men (24.24 versus 24.41), but there was no sex difference in African Americans (24.07 for both men and women). We speculate that selection pressures in Europe made men develop a slightly longer period than women to help them track dawn which could be useful for hunters, but less important for women as gatherers. © 2017 The Authors. Journal of Sleep Research published by John Wiley & Sons Ltd on behalf of European Sleep Research Society.

  15. NPP construction cost in Canada

    International Nuclear Information System (INIS)

    Gorshkov, A.L.

    1988-01-01

    The structure of capital costs during NPP construction in Canada is considered. Capital costs comprise direct costs (cost of the ground and ground rights, infrastructure, reactor equipment, turbogenerators, electrotechnical equipment, auxiliary equipment), indirect costs (construction equipment and services, engineering works and management services, insurance payments, freight, training, operating expenditures), capital per cents for the period of construction and cost of heavy water storages. It proceeds from the analysis of the construction cost structure for a NPP with the CANDU reactor of unit power of 515, 740 and 880 MW, that direct costs make up on the average 62%

  16. Constructing Catalonia

    Directory of Open Access Journals (Sweden)

    Bill Philips

    2009-07-01

    Full Text Available Catalonia, in common with other nations, has long been concerned with the question of identity and difference. Its problematic relationship with Spain has led to an emphasis on differentiating itself from its larger neighbour (if we are to accept, as most Spaniards do not, that Catalonia is not Spain, a situation complicated by the loss of the Spanish colonies of Cuba and The Philippines in 1898, and the Spanish Civil War and subsequent dictatorship from 1936 to 1976. Beginning in the late nineteenth century, the construction of a Catalan identity followed a similar route to that taken by other European nations such as England, Ireland and, indeed, Spain, including an emphasis on rural values, activities and the countryside, and the conversion of specifically local traditions into national past times. It is only in the last ten years or so that this model of Catalan identity has been recognised for what it is – a model constructed and encouraged for and by specific nationalist political interests. Ironically, Catalonia’s identity abroad has also been constructed and manipulated for political purposes, but from quite a different perspective. Orwell’s /Homage to Catalonia/ (1938 narrates an extremely blinkered version of the Spanish Civil War which has achieved iconic status as a result of cold war politics. Subsequent portrayals of the Spanish Civil War – Valentine Cunningham’s /The Penguin Book of Spanish Civil War Verse/ (ed., Penguin, 1980, or Ken Loach’s 1995 film /Land and Freedom/ base their arguments unquestioningly on /Homage to Catalonia/, perpetuating a view of the nation’s recent history that is both reductive and inaccurate

  17. Layout Construction

    DEFF Research Database (Denmark)

    Frandsen, Gudmund Skovbjerg; Palsberg, Jens; Schmidt, Erik Meineche

    We design a system for generating newspaper layout proposals. The input to the system consists of editorial information (text, pictures, etc) and style information (non-editorial information that specifies the aesthetic appearance of a layout). We consider the automation of layout construction...... to pose two main problems. One problem consists in optimizing the layout with respect to the constraints and preferences specified in the style information. Another problem consists in finding a representation of the style information that both supports its use in the combinatorial optimization...

  18. Wear Fast, Die Young: More Worn Teeth and Shorter Lives in Iberian Compared to Scottish Red Deer.

    Science.gov (United States)

    Pérez-Barbería, F J; Carranza, J; Sánchez-Prieto, C

    2015-01-01

    Teeth in Cervidae are permanent structures that are not replaceable or repairable; consequently their rate of wear, due to the grinding effect of food and dental attrition, affects their duration and can determine an animal's lifespan. Tooth wear is also a useful indicator of accumulative life energy investment in intake and mastication and their interactions with diet. Little is known regarding how natural and sexual selection operate on dental structures within a species in contrasting environments and how these relate to life history traits to explain differences in population rates of tooth wear and longevity. We hypothesised that populations under harsh environmental conditions should be selected for more hypsodont teeth while sexual selection may maintain similar sex differences within different populations. We investigated the patterns of tooth wear in males and females of Iberian red deer (Cervus elaphus hispanicus) in Southern Spain and Scottish red deer (C. e. scoticus) across Scotland, that occur in very different environments, using 10343 samples from legal hunting activities. We found higher rates of both incisor and molar wear in the Spanish compared to Scottish populations. However, Scottish red deer had larger incisors at emergence than Iberian red deer, whilst molars emerged at a similar size in both populations and sexes. Iberian and Scottish males had earlier tooth depletion than females, in support of a similar sexual selection process in both populations. However, whilst average lifespan for Iberian males was 4 years shorter than that for Iberian females and Scottish males, Scottish males only showed a reduction of 1 year in average lifespan with respect to Scottish females. More worn molars were associated with larger mandibles in both populations, suggesting that higher intake and/or greater investment in food comminution may have favoured increased body growth, before later loss of tooth efficiency due to severe wear. These results

  19. Toward an Organic Chemist's Periodic Table.

    Science.gov (United States)

    Hall, H. K., Jr.

    1980-01-01

    An analogy between electron transfer reactions of the elements and those of organic molecules is offered. Examples of organic electron transfer reactions are presented. The rationale of constructing an organic chemists' periodic table is also discussed. (HM)

  20. Advanced construction methods in ACR

    International Nuclear Information System (INIS)

    Elgohary, M.; Choy, E.; Yu, S.K.W.

    2002-01-01

    The ACR - Advanced CANDU Reactor, developed by Atomic Energy of Canada Limited (AECL), is designed with constructability considerations as a major requirement during all project phases from the concept design stage to the detail design stage. This necessitated a much more comprehensive approach in including constructability considerations in the design to ensure that the construction duration is met. For the ACR-700, a project schedule of 48 months has been developed for the nth replicated unit with a 36 month construction period duration from First Concrete to Fuel Load. An overall construction strategy that builds on the success of the construction methods that are proven in the construction of the Qinshan CANDU 6 project has been developed for the ACR. The overall construction strategy comprises the 'Open Top' construction technique using a Very Heavy Lift crane, parallel construction activities, with extensive modularization and prefabrication. In addition, significant applications of up to date construction technology will be implemented, e.g. large volume concrete pours, prefabricated rebar, use of climbing forms, composite structures, prefabricated permanent formwork, automatic welding, and utilization of the latest electronic technology tools such as 3D CADDs modelling yields a very high quality, clash free product to allow construction to be completed 'right the first time' and eliminates rework. Integration of 3D CADDs models and scheduling tools such as Primavera has allowed development of actual construction sequences and an iterative approach to schedule verification and improvement. Modularization and prefabrication are major features of the ACR design in order to achieve the project schedule. For the reactor building approximately 80% of the volume will be installed as modules or prefabricated assembles. This ensures critical path activities are achieved. This paper examines the advanced construction methods implemented in the design in order to

  1. 从麦金太尔的德性理论谈新时期我国体育职业道德建设%Enlightenment of sports professional ethics construction in the new period of China from MacIntyre's virtue theory

    Institute of Scientific and Technical Information of China (English)

    樊云庆; 曹景川

    2016-01-01

    德性的缺乏是导致新时期我国体育职业道德问题层出不穷的原因之一,而麦金太尔的德性论为解决体育职业道德问题提供了新的思路。从德性理论的概述出发,系统介绍了新时期我国体育职业道德建设的成就及职业道德缺失的现实问题,结合德性理论的实践、人生统一性与传统三大观点,探讨了德性理论对新时期我国体育职业道德建设的深刻启示,构建与我国现代社会经济条件相适应的职业道德体系。%In the new period,virtue deficiency is the fundamental reason leading to the increasingly serious sports moral issues in China,However,Macintyre's virtue theory offers a new idea to solve the sports professional ethic issues.Starting from an overview of virtue theory, this paper systematicly introduced the achievements of the sports professional ethics construction and the practical problems of virtue deficiency in the new period of China. With the combination of three viewpoints of the practice of virtue theory,lifetime unity and tradition,it discussed the profound enlightenment of virtue theory for the sports professional ethics construction in the new period of China,so as to establish a suitable professional ethic system fitting in the social and economic condition of China.

  2. Evolution of periodicity in periodical cicadas.

    Science.gov (United States)

    Ito, Hiromu; Kakishima, Satoshi; Uehara, Takashi; Morita, Satoru; Koyama, Takuya; Sota, Teiji; Cooley, John R; Yoshimura, Jin

    2015-09-14

    Periodical cicadas (Magicicada spp.) in the USA are famous for their unique prime-numbered life cycles of 13 and 17 years and their nearly perfectly synchronized mass emergences. Because almost all known species of cicada are non-periodical, periodicity is assumed to be a derived state. A leading hypothesis for the evolution of periodicity in Magicicada implicates the decline in average temperature during glacial periods. During the evolution of periodicity, the determinant of maturation in ancestral cicadas is hypothesized to have switched from size dependence to time (period) dependence. The selection for the prime-numbered cycles should have taken place only after the fixation of periodicity. Here, we build an individual-based model of cicadas under conditions of climatic cooling to explore the fixation of periodicity. In our model, under cold environments, extremely long juvenile stages lead to extremely low adult densities, limiting mating opportunities and favouring the evolution of synchronized emergence. Our results indicate that these changes, which were triggered by glacial cooling, could have led to the fixation of periodicity in the non-periodical ancestors.

  3. Purchasing management experience of Haiyang nuclear power project construction period

    International Nuclear Information System (INIS)

    Ma Yuqin

    2013-01-01

    Purchasing is one of the important aspects to ensure the safety and quality of the nuclear power plant. This paper, combining the purchasing peculiarity and purchasing process of Haiyang nuclear power project, summarizes experiences of Haiyang nuclear power project in promoting its purchasing management level in aspects of purchasing method choosing, purchasing plan management, purchasing process optimization, purchasing contract implementation and purchasing surveillance, etc. (author)

  4. High lung cancer surgical procedure volume is associated with shorter length of stay and lower risks of re-admission and death

    DEFF Research Database (Denmark)

    Møller, Henrik; Riaz, Sharma P; Holmberg, Lars

    2016-01-01

    It is debated whether treating cancer patients in high-volume surgical centres can lead to improvement in outcomes, such as shorter length of hospital stay, decreased frequency and severity of post-operative complications, decreased re-admission, and decreased mortality. The dataset for this anal......It is debated whether treating cancer patients in high-volume surgical centres can lead to improvement in outcomes, such as shorter length of hospital stay, decreased frequency and severity of post-operative complications, decreased re-admission, and decreased mortality. The dataset...... to their geographical population. Higher volume hospitals had shorter length of stay and the odds of re-admission were 15% lower in the highest hospital volume quintile compared with the lowest quintile. Mortality risks were 1% after 30 d and 3% after 90 d. Patients from hospitals in the highest volume quintile had...

  5. Sterol 27-Hydroxylase Polymorphism Significantly Associates With Shorter Telomere, Higher Cardiovascular and Type-2 Diabetes Risk in Obese Subjects

    Directory of Open Access Journals (Sweden)

    Sofia Pavanello

    2018-06-01

    Full Text Available Background/objectivesThe pathologic relationship linking obesity and lipid dismetabolism with earlier onset of aging-related disorders, including cardiovascular disease (CVD and type-2 diabetes (T2D, is not fully elucidate. Chronic inflammatory state, in obese individuals, may accelerate cellular aging. However, leukocyte telomere length (LTL, the cellular biological aging indicator, is elusively linked with obesity. Recent studies indicate that sterol 27-hydroxylase (CYP27A1 is an emerging antiatherogenic enzyme, that, by converting extrahepatic cholesterol to 27-hydroxycholesterol, facilitates cholesterol removal via high-density lipoprotein-cholesterol (HDL-C. We tested the hypothesis that obese subjects who carry at least three copies of CYP27A1 low-hydroxylation (LH activity genome-wide-validated alleles (rs4674345A, rs1554622A, and rs4674338G present premature aging, as reflected in shorter LTL and higher levels of CVD/T2D risk factors, including reduced HDL-C.Subjects/methodsObese subjects from SPHERE project {n = 1,457; overweight [body mass index (BMI 25–30 kg/m2] 65.8% and severe-obese (BMI > 30 kg/m2 34.2%} were characterized for the presence from 0 to 6 LH-CYP27A1 allele copy number. Univariate and multivariable sex–age–smoking-adjusted linear-regression models were performed to compare CVD/T2D risk factors and biological aging (LTL in relation to the combined BMI-LH groups: overweight-LH: 0–2, overweight-LH: 3–6, severe-obese-LH: 0–2, and severe-obese-LH: 3–6.ResultsHigher LTL attrition was found in severe-obese than overweight individuals (p < 0.001. Multivariable model reveals that among severe-obese patients those with LH: 3–6 present higher LTL attrition than LH: 0–2 (p < 0.05. Univariate and multivariable models remarkably show that insulin resistance is higher both in overweight-LH: 3–6 vs overweight-LH: 0–2 (p < 0.001 and in severe-obese-LH: 3–6 vs severe-obese-LH: 0–2 (p

  6. Periodic Table Target: A Game that Introduces the Biological Significance of Chemical Element Periodicity

    Science.gov (United States)

    Sevcik, Richard S.; McGinty, Ragan L.; Schultz, Linda D.; Alexander, Susan V.

    2008-01-01

    Periodic Table Target, a game for middle school or high school students, familiarizes students with the form of the periodic table and the biological significance of different elements. The Periodic Table Target game board is constructed as a class project, and the game is played to reinforce the content. Students are assigned several elements…

  7. 36 CFR 14.29 - Timely construction.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Timely construction. 14.29...-OF-WAY Procedures § 14.29 Timely construction. (a) Unless otherwise provided by law, a period of up to five years from the date a right-of-way is granted is allowed for completion of construction...

  8. Inflation from periodic extra dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Higaki, Tetsutaro [Department of Physics, Keio University, Kanagawa 223-8522 (Japan); Tatsuta, Yoshiyuki, E-mail: thigaki@rk.phys.keio.ac.jp, E-mail: y_tatsuta@akane.waseda.jp [Department of Physics, Waseda University, Tokyo 169-8555 (Japan)

    2017-07-01

    We discuss a realization of a small field inflation based on string inspired supergravities. In theories accompanying extra dimensions, compactification of them with small radii is required for realistic situations. Since the extra dimension can have a periodicity, there will appear (quasi-)periodic functions under transformations of moduli of the extra dimensions in low energy scales. Such a periodic property can lead to a UV completion of so-called multi-natural inflation model where inflaton potential consists of a sum of multiple sinusoidal functions with a decay constant smaller than the Planck scale. As an illustration, we construct a SUSY breaking model, and then show that such an inflaton potential can be generated by a sum of world sheet instantons in intersecting brane models on extra dimensions containing orbifold. We show also predictions of cosmic observables by numerical analyzes.

  9. Periodicity, the Canon and Sport

    Directory of Open Access Journals (Sweden)

    Thomas F. Scanlon

    2015-10-01

    Full Text Available The topic according to this title is admittedly a broad one, embracing two very general concepts of time and of the cultural valuation of artistic products. Both phenomena are, in the present view, largely constructed by their contemporary cultures, and given authority to a great extent from the prestige of the past. The antiquity of tradition brings with it a certain cachet. Even though there may be peripheral debates in any given society which question the specifics of periodization or canonicity, individuals generally accept the consensus designation of a sequence of historical periods and they accept a list of highly valued artistic works as canonical or authoritative. We will first examine some of the processes of periodization and of canon-formation, after which we will discuss some specific examples of how these processes have worked in the sport of two ancient cultures, namely Greece and Mesoamerica.

  10. 42 CFR 137.78 - May a Self-Governance Tribe negotiate a funding agreement for a term longer or shorter than one...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false May a Self-Governance Tribe negotiate a funding agreement for a term longer or shorter than one year? 137.78 Section 137.78 Public Health PUBLIC HEALTH... SERVICES TRIBAL SELF-GOVERNANCE Funding General § 137.78 May a Self-Governance Tribe negotiate a funding...

  11. Discrimination of Urban Spaces with Different Level of Restorativeness Based on the Original and on a Shorter Version of Hartig et al.’s Perceived Restorativeness Scale

    Directory of Open Access Journals (Sweden)

    Fátima Negrín

    2017-10-01

    Full Text Available Restorativeness is defined as the potential of the environment to re-establish certain cognitive capacities related to human information processing. The most frequently used instrument for evaluating the restorativeness of places is the Perceived Restorativeness Scale, proposed by Hartig et al. (1991. Later on, shorter versions of the Perceived Restorativeness Scale were proposed. The aim of this work is to evaluate the discriminatory capacity of the original and of a shorter Spanish version of the PRS, considering urban settings previously selected for having different level of restorativeness, according to expert’s criteria. The study involved 244 students and used a 3 × 2 mixed experimental design, with two independent variables: Restorativeness of a place (between-subjects, which was manipulated by showing pictures of settings selected with varying levels of restorativeness (high, medium, low, and length of the scale (within-subjects, which was manipulated by asking subjects to fill in both the original and a shorter version of the PRS. The order of presentation of the two scales was counterbalanced. Results show an appropriate reliability for both version of the scale. Items of being-away, fascination, and coherence of the shorter scale correlate more strongly with the corresponding factor of the original scale, compared to the others factors. Both scales produce similar values for the perceived restorativeness of the different places, except for places with low restorativeness.

  12. Cost-effectiveness of longer-term versus shorter-term provision of antibiotics in patients with persistent symptoms attributed to Lyme disease

    NARCIS (Netherlands)

    Berende, A.; Nieuwenhuis, L.; Hofstede, H.J.M. ter; Vos, F.J.; Vogelaar, M.L.; Tromp, M.A.; Middendorp, H. van; Donders, A.R.T.; Evers, A.W.M.; Kullberg, B.J.; Adang, E.M.M.

    2018-01-01

    BACKGROUND: The treatment of persistent symptoms attributed to Lyme disease remains controversial. Recently, the PLEASE study did not demonstrate any additional clinical benefit of longer-term versus shorter-term antibiotic treatment. However, the economic impact of the antibiotic strategies has not

  13. The effect of shorter exposure versus prolonged exposure on treatment outcome in Tourette syndrome and chronic tic disorders - an open trial.

    Science.gov (United States)

    van de Griendt, Jolande M T M; van Dijk, Maarten K; Verdellen, Cara W J; Verbraak, Marc J P M

    2018-01-11

    Exposure and response prevention has shown to be an effective strategy and is considered a first-line intervention in the behavioural treatment of tic disorders. Prior research demonstrated significant tic reduction after 12 two hour sessions. In this open trial, the question is addressed whether, relative to these prolonged sessions, exposure sessions of shorter duration yield differential outcome for patients with tic disorders. A total of 29 patients diagnosed with Tourette syndrome (TS) or chronic tic disorder were treated with shorter exposure sessions (1 h), and these data were compared to the data from a study about prolonged exposure (2 h, n = 21). Outcome was measured by the Yale Global Tic Severity Scale (YGTSS). Results suggest that after taking the difference in illness duration between the two groups into account, the effectiveness of shorter exposure sessions is not inferior to that of prolonged exposure. Results suggest that treatment with shorter exposure might be more efficient and more patients can be reached. Future research is needed to gain more insight into the mechanisms underlying the efficacy of behavioural treatments for tics.

  14. N-Terminal Domains in Two-Domain Proteins Are Biased to Be Shorter and Predicted to Fold Faster Than Their C-Terminal Counterparts

    Directory of Open Access Journals (Sweden)

    Etai Jacob

    2013-04-01

    Full Text Available Computational analysis of proteomes in all kingdoms of life reveals a strong tendency for N-terminal domains in two-domain proteins to have shorter sequences than their neighboring C-terminal domains. Given that folding rates are affected by chain length, we asked whether the tendency for N-terminal domains to be shorter than their neighboring C-terminal domains reflects selection for faster-folding N-terminal domains. Calculations of absolute contact order, another predictor of folding rate, provide additional evidence that N-terminal domains tend to fold faster than their neighboring C-terminal domains. A possible explanation for this bias, which is more pronounced in prokaryotes than in eukaryotes, is that faster folding of N-terminal domains reduces the risk for protein aggregation during folding by preventing formation of nonnative interdomain interactions. This explanation is supported by our finding that two-domain proteins with a shorter N-terminal domain are much more abundant than those with a shorter C-terminal domain.

  15. Constructability - from Qinshan to the ACR

    International Nuclear Information System (INIS)

    Elgohary, M.; Fairclough, N.; Ricciuti, R.

    2003-01-01

    AECL has recognised the importance of Constructability for many years and is applying its principals to CANDU projects with increasing success. Constructability is defined as the consideration of construction knowledge and experience during all phases of a project, and recognizes that maximum benefit can be achieved during the concept phases of a project. The CANDU 6 Nuclear Power Plant has been constructed eleven times in the last 25 years, however, the last two units being completed on the Qinshan project in China have employed some very innovative construction methods that have not been used on the previous units. In order to make nuclear power generation more competitive, shorter construction schedules and reduced project costs and risks are essential objectives. The application of constructability principles is a major contributor to achieving these objectives. The success of Qinshan has increased the confidence in the new construction methods which are being implemented on the ACR (Advanced CANDU Reactor) successfully. An ACR construction strategy that utilizes advanced construction techniques has been developed by AECL. The strategy includes paralleling of activities by using extensive modularization and the vertical installation of equipment and modules into the reactor building, using a VHL (Very Heavy Lift) crane. This strategy allows short schedules to be met with a minimum risk to the project. This paper describes the latest construction methods used successfully on the Qinshan CANDU 6 project and looks at the extensive implementation of similar methods for ACR. It is concluded, based on the Qinshan success, that the ACR construction schedule is readily achievable. (author)

  16. Construction and commissioning experience of evolutionary water cooled nuclear power plants

    International Nuclear Information System (INIS)

    2004-04-01

    Electricity market liberalization is an established fact in several countries and there is a trend to adopt it in other countries. The essential aim of market liberalization is to improve the overall economic efficiency. In order that nuclear power remains a viable option for electricity generation, its costs should be competitive with alternative sources while, at the same time, it should have a safe and reliable operation record. The capital cost of nuclear power plants (NPPs) generally accounts for 43-70% of the total nuclear electricity generation costs, compared to 26-48% for coal plants and 13-32% for gas plants. Most of these expenditures are incurred during the construction phase of a NPP. The achievement of shorter construction periods using improved technology and construction methods has a significant benefit on the costs incurred prior to any production of electricity. This document is intended to make the recent worldwide experience on construction and commissioning of evolutionary water cooled NPPs available to Member States and especially to those with nuclear power plants under construction/planning, and to those seriously considering nuclear power projects in the future. The final aim is to assist utilities and other organizations in Member States to improve the construction of nuclear power plants and achieve shortened schedules and reduced costs without compromising quality and safety. This document aims to provide an overview of the most advanced technologies, methods and processes used in construction and commissioning of recent nuclear projects. To better achieve this objective the presentation is selectively focused more on the new developments rather than providing a full review of all issues related to construction and commissioning. The experience described in this TECDOC applies to managers, engineers, supervisors, technicians and workers in various organizations dealing with the site construction and commissioning of nuclear power plants

  17. Japanese experience in nuclear power plant construction

    International Nuclear Information System (INIS)

    Seko, T.

    1989-01-01

    Development of LWR in JAPAN started by introducing LWR from the U.S.A. Since then we have been improving existing technology and promoting domestic technology development based on experiences accumulated in Japan. As a result, recent operating performance has been excellent. As far as construction work is concerned, we also have been making our best efforts to improve the performance of construction work itself, with the cooperation of manufacturers. As for construction work, we have succeeded in improving the quality of construction work, shortening the construction period and reducing construction costs through new technology and Japanese-style work management

  18. A construction process model for implementing constructability in construction

    NARCIS (Netherlands)

    Langkemper, J.; Al-Jibouri, S.; Reymen, I.M.M.J.; Maas, G.J.; Gassel, van F.

    2003-01-01

    In construction, failure of design professionals to consider how a builder will implement the design can result in scheduling problems, cost escalation, delays and disputes during the construction process. The integration of construction knowledge and experience during planning and design is termed

  19. Periodic and quasiperiodic revivals in periodically driven interacting quantum systems

    Science.gov (United States)

    Luitz, David J.; Lazarides, Achilleas; Bar Lev, Yevgeny

    2018-01-01

    Recently it has been shown that interparticle interactions generically destroy dynamical localization in periodically driven systems, resulting in diffusive transport and heating. In this Rapid Communication we rigorously construct a family of interacting driven systems which are dynamically localized and effectively decoupled from the external driving potential. We show that these systems exhibit tunable periodic or quasiperiodic revivals of the many-body wave function and thus of all physical observables. By numerically examining spinless fermions on a one-dimensional lattice we show that the analytically obtained revivals of such systems remain stable for finite systems with open boundary conditions while having a finite lifetime in the presence of static spatial disorder. We find this lifetime to be inversely proportional to the disorder strength.

  20. Industrial Disputes in the Construction Sector

    Directory of Open Access Journals (Sweden)

    L.J Perry

    2012-11-01

    Full Text Available The Cole Royal Commission enquiry into the building and construction (abbreviated to ‘construction’ sector recommended controversial workplace-relation reforms for that sector. The recommended changes are likely to be enshrined in legislation within the year. The Commission drew on analyses of industrial disputes that focused, in the main, on quite recent experience. This paper attempts to give a broader historical perspective on disputes in that sector by considering the pattern of disputes for the entire post-World War II period. Accordingly, data on disputes and employees during the entire period are gathered from Australian Bureau of Statistics current and archived sources. These data are classified according to sector (construction versus non-construction and analysed. It is found that the strike rate has, on average, been greater in the construction sector than in the non-construction sector. However, there have been periods during which disputes in the construction sector have been relatively low. The most recent period was during the period of the Accord (1983-96, during which the strike rate in the construction sector fell relatively strongly. The analysis of this relatively broad historical period draws attention, among other things, to the possibility that the sort of strategies employed during the Accord years – strategies of cooperation and consensus building – may provide a more effective means of bringing industrial peace to the workplace relations scene of the construction sector than policies that are relatively confrontational.

  1. Development of new construction technologies for nuclear power plant

    International Nuclear Information System (INIS)

    Kawamata, Susumu; Itoh, Daisuke; Ichizono, Katsuyuki

    1995-01-01

    In order to proceed rationally with the construction of a nuclear power station, the followings are the subject to solve beside reducing the construction cost: shortening the construction period, improving the quality, and securing safety in the construction work. As a measure to solve the matters, we correctly construct the plant mainly applying 'all-weather proof construction method' and 'pre-assembled large-block construction method'. Furthermore, as the plant construction control system, we perform a construction work applying the design change management system, pre-assessment for safety, and the whole facility check. As a result of our effort, it was attained that when we compare the matured plant with the first unit, the construction cost is reduced by 30%, the construction period is shortened by 12 months, site manpower is decreased by 30%, and the plant had no sudden shutdowns even during the trial operation period. (author)

  2. Shorter Leukocyte Telomere Length in Relation to Presumed Nonalcoholic Fatty Liver Disease in Mexican-American Men in NHANES 1999–2002

    Directory of Open Access Journals (Sweden)

    Janet M. Wojcicki

    2017-01-01

    Full Text Available Leukocyte telomere length is shorter in response to chronic disease processes associated with inflammation such as diabetes mellitus and coronary artery disease. Data from the National Health and Nutrition Examination Survey (NHANES from 1999 to 2002 was used to explore the relationship between leukocyte telomere length and presumed NAFLD, as indicated by elevated serum alanine aminotransferase (ALT levels, obesity, or abdominal obesity. Logistic regression models were used to evaluate the relationship between telomere length and presumed markers of NAFLD adjusting for possible confounders. There was no relationship between elevated ALT levels, abdominal obesity, or obesity and telomere length in adjusted models in NHANES (OR 1.13, 95% CI 0.48–2.65; OR 1.17, 95% CI 0.52–2.62, resp.. Mexican-American men had shorter telomere length in relation to presumed NAFLD (OR 0.07, 95% CI 0.006–0.79 and using different indicators of NAFLD (OR 0.012, 95% CI 0.0006–0.24. Mexican origin with presumed NAFLD had shorter telomere length than men in other population groups. Longitudinal studies are necessary to evaluate the role of telomere length as a potential predictor to assess pathogenesis of NALFD in Mexicans.

  3. The Periodic Pyramid

    Science.gov (United States)

    Hennigan, Jennifer N.; Grubbs, W. Tandy

    2013-01-01

    The chemical elements present in the modern periodic table are arranged in terms of atomic numbers and chemical periodicity. Periodicity arises from quantum mechanical limitations on how many electrons can occupy various shells and subshells of an atom. The shell model of the atom predicts that a maximum of 2, 8, 18, and 32 electrons can occupy…

  4. Book Reviews in Periodicals.

    Science.gov (United States)

    Ettelt, Harold J.

    All recent issues of periodicals found which contain indexed book reviews are listed in this compilation from Drake Memorial Library at the New York State University at Brockport. The periodicals are listed by 29 subject headings in this informal guide designed to be used at Drake Library. The number of reviews in the periodical in a recent year…

  5. On almost-periodic points of a topological Markov chain

    International Nuclear Information System (INIS)

    Bogatyi, Semeon A; Redkozubov, Vadim V

    2012-01-01

    We prove that a transitive topological Markov chain has almost-periodic points of all D-periods. Moreover, every D-period is realized by continuously many distinct minimal sets. We give a simple constructive proof of the result which asserts that any transitive topological Markov chain has periodic points of almost all periods, and study the structure of the finite set of positive integers that are not periods.

  6. Constructibility assessment of APR1400

    International Nuclear Information System (INIS)

    Cho, Sung Jae; Kang, Yong Chul; Lee, Jae Gon; Lim, Woo Sang

    2003-01-01

    APR1400 (formerly KNGR) development is one of national G-7 projects sponsored by government and KHNP (Korea Hydro and Nuclear Power Co., LTD). It is an evolutionary standard reactor with the thermal output of 4000MWt and has been adopted for Shin-Kori Unit 3 and 4. The government organizations, research institutes, universities and industries have participated in the project since 1992 along with KHNP, and the standard design certification program was issued in May 2002. The project set up the top-tier requirements about the safety, economy, operability and maintainability, and constructibility in the early design stage. The requirements have been evaluated periodically during the design process, and the results were reflected to the design. This paper describes the methods for constructibility enhancement and the results of schedule analysis to assure meeting construction duration target, which is set to 48 months from the first concrete pouring to the commercial operation on the condition that learning effects are maximized at Nth plant. To meet the target schedule, the design characteristics and constructibility studies such as new construction methods and construction schedule analysis were performed. The new construction methods presented here are over the top method for NSSS components, deck plate and steel from for concrete wall and slab, automatic welding for large bore piping, and modularization of components and structure, etc. (author)

  7. Collapse simulation of building constructions

    Directory of Open Access Journals (Sweden)

    Nekrest'yanov Viktor Nikolaevich

    Full Text Available The physical reasons for building structures destruction are both the forces arising at stress-strain state of construction elements and external influences arising at emergency situations, as well as their moments, impulses and periodic impulses with the frequencies close to of fluctuations frequencies of construction elements. We shall call the mathematical calculation models for the parameters-reasons of destructions the basic models. The basic models of destruction of building structures elements allow not only providing necessary level of reliability and survivability of the elements and the construction as a whole already at the stage of their design, but also giving the chance, at their corresponding completion, to provide rational decisions on the general need of recovery works and their volume depending on destruction level. Especially important for rational design decisions development, which ensure the demanded constructional safety of building structures, is library creation of the basic mathematical models of standard processes of bearing elements destructions for standard construction designs for the purpose of the further forecast (assessment of the level and probabilities of standard destructions. Some basic mathematical models of destructions processes of the standard elements of building structures are presented in the present article. A model of accounting for construction defects and a model of obtaining requirements to probabilities of partial destructions of a construction are given. Both of these models are probabilistic.

  8. Hitachi's experience and achievements in ABWR construction

    International Nuclear Information System (INIS)

    Inoue, Takashi; Miura, Jun; Murayama, Kouichi

    2003-01-01

    Hitachi, Ltd. (Hitachi) is taking charge of the turbine island of Chubu Electric Power Company's Hamaoka nuclear power plant Unit No. 5 (Hamaoka 5), and all facilities of Hokuriku Electric Power Company's Shika Nuclear Power Station Unit No. 2 (Shika 2). Hitachi has achieved shorter schedules and lower costs in the two projects with the following construction methods. First, Hitachi applied modularization and the area-by-area method. These methods enable us to undertake building and installation work in parallel. Second, the floor packaging construction method enables us to finish installation in every area earlier than conventional methods. Moreover, manpower can be distributed evenly. This paper reports the application of these advanced construction methods to the Hamaoka 5 and Shika 2 projects. Installations such as RCCV modules and condenser blocks are presented in this paper. In addition, Hitachi is using 3D-CAD engineering and our own construction management system to optimize the planning of construction procedures and the installation of equipment in these projects. Thus Hitachi is always striving to improve the reliability, safety and economy of ABWR construction technologies. (author)

  9. Constructing Aligned Assessments Using Automated Test Construction

    Science.gov (United States)

    Porter, Andrew; Polikoff, Morgan S.; Barghaus, Katherine M.; Yang, Rui

    2013-01-01

    We describe an innovative automated test construction algorithm for building aligned achievement tests. By incorporating the algorithm into the test construction process, along with other test construction procedures for building reliable and unbiased assessments, the result is much more valid tests than result from current test construction…

  10. Perspectives of construction robots

    Science.gov (United States)

    Stepanov, M. A.; Gridchin, A. M.

    2018-03-01

    This article is an overview of construction robots features, based on formulating the list of requirements for different types of construction robots in relation to different types of construction works.. It describes a variety of construction works and ways to construct new or to adapt existing robot designs for a construction process. Also, it shows the prospects of AI-controlled machines, implementation of automated control systems and networks on construction sites. In the end, different ways to develop and improve, including ecological aspect, the construction process through the wide robotization, creating of data communication networks and, in perspective, establishing of fully AI-controlled construction complex are formulated.

  11. Earth Noise in the 20- to 100-Second Period Range

    Science.gov (United States)

    1975-09-09

    instruments were incapable of following fluctuations of shorter periods.) Gretener (1967) obtained similar results. Both of these workers...found indica- tions that the convection eddies believed to exist were comparable to the hole diameter in vertical extent. Both Gretener (1967...Heat flow in Western Canada: geoph. J., v. 6, p. 245-261. Gretener , P. E., 1967, On the thermal instability of large diameter wells: geophysics, J32

  12. Construction completion report

    International Nuclear Information System (INIS)

    1990-01-01

    This Construction Completion Report documents the major construction projects at the Waste Isolation Pilot Plant (WIPP) site and related information on contracts, schedules, and other areas which affected construction. This report is not intended to be an exhaustive detailed analysis of construction, but is a general overview and summary of the WIPP construction. 10 refs., 29 figs

  13. Non-shoring construction for T/G pedestal beams

    International Nuclear Information System (INIS)

    Abe, T.

    1992-01-01

    The T/G pedestal construction work has been the critical path within the T/B construction work of BWR type nuclear power plant. In order to meet the requirement of shortening the construction period and improved in safety on a Turbine Building (T/B) construction work, Non-soring construction for T/G Pedestal Beams was developed. By applying this method to T/G pedestal construction work, we succeeded in shortening the T/B construction period and improvement in safety significantly. (author)

  14. Urban blackbirds have shorter telomeres

    NARCIS (Netherlands)

    Ibanez-Alamo, Juan Diego; Pineda-Pampliega, Javier; Thomson, Robert L.; Aguirre, Jose I.; Diez-Fernandez, Alazne; Faivre, Bruno; Figuerola, Jordi; Verhulst, Simon

    Urbanization, one of the most extreme human-induced environmental changes, represents a major challenge for many organisms. Anthropogenic habitats can have opposing effects on different fitness components, for example, by decreasing starvation risk but also health status. Assessment of the net

  15. Painful menstrual periods

    Science.gov (United States)

    Menstruation - painful; Dysmenorrhea; Periods - painful; Cramps - menstrual; Menstrual cramps ... into two groups, depending on the cause: Primary dysmenorrhea Secondary dysmenorrhea Primary dysmenorrhea is menstrual pain that ...

  16. Middle Helladic Period

    DEFF Research Database (Denmark)

    Sarri, Kalliopi

    1999-01-01

    and their quality was improved considerably toward the end of this period. The profound cultural innovations of the Middle Helladic period were initially interpreted as a result of violent population movement and troubles provoked by the coming of the first Indo-European races. However, this matter does no more...... Helladic period is considered as a period of economic and social decline it was the time during which the mainland features merged with the insular influence, that is all the Aegean elements which led to the creation of the Mycenaean civilization were mixed in a creative way....

  17. Systemic lupus erythematosus and vitamin D deficiency are associated with shorter telomere length among African Americans: a case-control study.

    Directory of Open Access Journals (Sweden)

    Brett M Hoffecker

    Full Text Available Systemic lupus erythematosus (SLE is a chronic systemic autoimmune disease that disproportionately affects African American females. The causes of SLE are unknown but postulated to be a combination of genetic predisposition and environmental triggers. Vitamin D deficiency is one of the possible environmental triggers. In this study we evaluated relationships between vitamin D status, cellular aging (telomere length and anti-telomere antibodies among African American Gullah women with SLE. The study population included African American female SLE patients and unaffected controls from the Sea Island region of South Carolina. Serum 25-hydroxyvitamin D levels were measured using a nonchromatographic radioimmunoassay. Telomere length was measured in genomic DNA of peripheral blood mononuclear cells (PBMCs by monochrome multiplex quantitative PCR. Anti-telomere antibody levels were measured by enzyme-linked immunosorbent assay (ELISA. Patients with SLE had significantly shorter telomeres and higher anti-telomere antibody titers compared to age- and gender-matched unaffected controls. There was a positive correlation between anti-telomere antibody levels and disease activity among patients and a significant correlation of shorter telomeres with lower 25-hydroxyvitamin D levels in both patients and controls. In follow-up examination of a subset of the patients, the patients who remained vitamin D deficient tended to have shorter telomeres than those patients whose 25-hydroxyvitamin D levels were repleted. Increasing 25-hydroxyvitamin D levels in African American patients with SLE may be beneficial in maintaining telomere length and preventing cellular aging. Moreover, anti-telomere antibody levels may be a promising biomarker of SLE status and disease activity.

  18. Long-Term Costs and Health Consequences of Issuing Shorter Duration Prescriptions for Patients with Chronic Health Conditions in the English NHS.

    Science.gov (United States)

    Martin, Adam; Payne, Rupert; Wilson, Edward Cf

    2018-06-01

    The National Health Service (NHS) in England spends over £9 billion on prescription medicines dispensed in primary care, of which over two-thirds is accounted for by repeat prescriptions. Recently, GPs in England have been urged to limit the duration of repeat prescriptions, where clinically appropriate, to 28 days to reduce wastage and hence contain costs. However, shorter prescriptions will increase transaction costs and thus may not be cost saving. Furthermore, there is evidence to suggest that shorter prescriptions are associated with lower adherence, which would be expected to lead to lower clinical benefit. The objective of this study is to estimate the cost-effectiveness of 3-month versus 28-day repeat prescriptions from the perspective of the NHS. We adapted three previously developed UK policy-relevant models, incorporating transaction (dispensing fees, prescriber time) and drug wastage costs associated with 3-month and 28-day prescriptions in three case studies: antihypertensive medications for prevention of cardiovascular events; drugs to improve glycaemic control in patients with type 2 diabetes; and treatments for depression. In all cases, 3-month prescriptions were associated with lower costs and higher QALYs than 28-day prescriptions. This is driven by assumptions that higher adherence leads to improved disease control, lower costs and improved QALYs. Longer repeat prescriptions may be cost-effective compared with shorter ones. However, the quality of the evidence base on which this modelling is based is poor. Any policy rollout should be within the context of a trial such as a stepped-wedge cluster design.

  19. Concrete construction engineering handbook

    CERN Document Server

    Nawy, Edward G

    2008-01-01

    Provides coverage of concrete construction engineering and technology. This work features discussions focusing on: the advances in engineered concrete materials; reinforced concrete construction; specialized construction techniques; and, design recommendations for high performance.

  20. Streamlined project closeout for construction at KYTC.

    Science.gov (United States)

    2017-09-01

    Project closeout is the period between the end of construction and when a contract is finalized. During closeout, resources are held in encumbered funds intended for the project and in the contractors bonding capacity. Although the Kentucky Transp...

  1. INDOT Construction Inspection Priorities : Technical Summary

    Science.gov (United States)

    2012-05-01

    In the last decade, the Indiana Department of Transportation (INDOT) increased the number of construction projects funded by capital made available through the leasing of the Indiana Toll Road. However, during the same time period, the level of perso...

  2. Interstitial lung abnormalities in treatment-naïve advanced non-small-cell lung cancer patients are associated with shorter survival

    Energy Technology Data Exchange (ETDEWEB)

    Nishino, Mizuki, E-mail: Mizuki_Nishino@DFCI.HARVARD.EDU [Department of Radiology, Brigham and Women' s Hospital, 75 Francis St., Boston, MA 02115 (United States); Department of Imaging, Dana-Farber Cancer Institute, 450 Brookline Ave., Boston, MA 02215 (United States); Cardarella, Stephanie [Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave., Boston, MA 02215, (United States); Dahlberg, Suzanne E. [Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Ave., Boston, MA 02215 (United States); Araki, Tetsuro [Department of Radiology, Brigham and Women' s Hospital, 75 Francis St., Boston, MA 02115 (United States); Lydon, Christine; Jackman, David M.; Rabin, Michael S. [Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave., Boston, MA 02215, (United States); Hatabu, Hiroto [Department of Radiology, Brigham and Women' s Hospital, 75 Francis St., Boston, MA 02115 (United States); Johnson, Bruce E. [Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave., Boston, MA 02215, (United States)

    2015-05-15

    Highlights: • Interstitial lung abnormalities were present in 14% of stage IV NSCLC patients. • ILA was more common in older patients with heavier smoking history. • ILA was associated with shorter survival after adjusting for smoking and therapy. • ILA could be an additional independent marker for survival in advanced NSCLC. - Abstract: Objective: Interstitial lung diseases are associated with increased risk of lung cancer. The prevalence of ILA at diagnosis of advanced non-small-cell lung cancer (NSCLC) and its impact on overall survival (OS) remain to be investigated. Materials and method: The study included 120 treatment-naïve stage IV NSCLC patients (53 males, 67 females). ILA was scored on CT prior to any systemic therapy using a 4-point scale [0 = no evidence of ILA, 1 = equivocal for ILA, 2 = suspicious for ILA, 3 = ILA] by a sequential reading method previously reported. ILA scores of 2 or 3 indicated the presence of ILA. Results: ILA was present in 17 patients (14%) with advanced NSCLC prior to any treatment (score3: n = 2, score2: n = 15). These 17 patients were significantly older (median age: 69 vs. 63, p = 0.04) and had a heavier smoking history (median: 40 vs. 15.5 pack-year, p = 0.003) than those with ILA score 0 or 1. Higher ILA scores were associated with shorter OS (p = 0.001). Median OS of the 17 patients with ILA was 7.2 months [95%CI: 2.9–9.4] compared to 14.8 months [95%CI: 11.1–18.4] in patients with ILA score 0 or 1 (p = 0.002). In a multivariate model, the presence of ILA remained significant for increased risk for death (HR = 2.09, p = 0.028) after adjusting for first-line systemic therapy (chemotherapy, p < 0.001; TKI, p < 0.001; each compared to no therapy) and pack years of smoking (p = 0.40). Conclusion: Radiographic ILA was present in 14% of treatment-naïve advanced NSCLC patients. Higher ILA scores were associated with shorter OS, indicating that ILA could be a marker of shorter survival in advanced NSCLC.

  3. NPP Krsko Periodic Safety Review action plan

    International Nuclear Information System (INIS)

    Bilic Zabric, T.

    2006-01-01

    In the current, internationally accepted, safety philosophy Periodic Safety Reviews (PSRs) are comprehensive reviews aimed at the verification that an operating NPP remains safe when judged against current safety objectives and practices and that adequate arrangements are in place to maintain an acceptable level of safety. These reviews are complementary to the routine and special safety reviews. They are long time-scale reviews intended to deal with the cumulative effects of plant ageing, modifications, operating experience and technical developments, which are not so easily comprehended over the shorter time-scale routine of safety reviews. The review was completed in 2005 and the next period will see the implementation of the action plan including some plant upgrades. The action plan lists issues that should be implemented at NPP Krsko together with associated milestones. The milestones were assumed based on best estimate resource availability and their ends can be potentially floated. In some cases, multiple corrective measures may be postulated to provide resolution for a given safety issue. The Slovenian Nuclear Safety Administration by decree approved the first periodic safety review and the implementation plan of activities arising from it. The entire implementation plan must be carried out by 15 October 2010. Report on the second periodic safety review must be submitted by the NEK not later than 15 December 2013. (author)

  4. Construction and testing of JT-60

    International Nuclear Information System (INIS)

    Kishimoto, H.; Aikawa, H.; Oikawa, A.; Miya, N.; Suzuki, K.; Ozeki, T.; Tokutake, T.; Kunieda, S.; Hiruta, K.; Hosoda, R.

    1987-01-01

    The JT-60 project is reviewed in terms of design, R and D, construction, commissioning and project management. Design features of JT-60 have been refined and renewed through periodic assessments. Engineering targets have been achieved by R and D efforts. Construction and commissioning have progressed on schedule with intensive project management and control. JT-60 obtained high performance and has entered into the experimental phase after completion of machine construction. (orig.)

  5. On some periodicity effects

    DEFF Research Database (Denmark)

    Sorokin, Sergey V.

    2015-01-01

    The talk is concerned with the modelling of wave propagation in and vibration of periodic elastic structures. Although analysis of wave-guide properties of infinite periodic structures is a well establish research subject, some issues have not yet been fully addressed in the literature. The aim o...

  6. The Living Periodic Table

    Science.gov (United States)

    Nahlik, Mary Schrodt

    2005-01-01

    To help make the abstract world of chemistry more concrete eighth-grade students, the author has them create a living periodic table that can be displayed in the classroom or hallway. This display includes information about the elements arranged in the traditional periodic table format, but also includes visual real-world representations of the…

  7. Reprint Series: Geometric Constructions. RS-10.

    Science.gov (United States)

    Schaaf, William L., Ed.

    This is one in a series of SMSG supplementary and enrichment pamphlets for high school students. The series makes available expository articles which appeared in a variety of mathematical periodicals. Topics covered include: (1) Euclidean constructions; (2) the geometry of the fixed compass; (3) certain topics related to constructions with…

  8. Is Alcohol Use Disorder Identification Test (AUDIT or its shorter versions more useful to identify risky drinkers in a Chinese population? A diagnostic study.

    Directory of Open Access Journals (Sweden)

    Benjamin H K Yip

    Full Text Available To examine the diagnostic performance of shorter versions of Alcohol Use Disorder Identification Test (AUDIT, including Alcohol Consumption (AUDIT-C, in identifying risky drinkers in primary care settings using conventional performance measures, supplemented by decision curve analysis and reclassification table.A cross-sectional study of adult males in general outpatient clinics in Hong Kong. The study included only patients who reported at least sometimes drinking alcoholic beverages. Timeline follow back alcohol consumption assessment method was used as the reference standard. A Chinese translated and validated 10-item AUDIT (Ch-AUDIT was used as a screening tool of risky drinking.Of the participants, 21.7% were classified as risky drinkers. AUDIT-C has the best overall performance among the shorter versions of Ch-AUDIT. The AUC of AUDIT-C was comparable to Ch-AUDIT (0.898 vs 0.901, p-value = 0.959. Decision curve analysis revealed that when the threshold probability ranged from 15-30%, the AUDIT-C had a higher net-benefit than all other screens. AUDIT-C improved the reclassification of risky drinking when compared to Ch-AUDIT (net reclassification improvement = 0.167. The optimal cut-off of AUDIT-C was at ≥5.Given the rising levels of alcohol consumption in the Chinese regions, this Chinese translated 3-item instrument provides convenient and time-efficient risky drinking screening and may become an increasingly useful tool.

  9. Bounded and Periodic Solutions of Semilinear Impulsive Periodic System on Banach Spaces

    Directory of Open Access Journals (Sweden)

    Wei W

    2008-01-01

    Full Text Available Abstract A class of semilinear impulsive periodic system on Banach spaces is considered. First, we introduce the -periodic PC-mild solution of semilinear impulsive periodic system. By virtue of Gronwall lemma with impulse, the estimate on the PC-mild solutions is derived. The continuity and compactness of the new constructed Poincaré operator determined by impulsive evolution operator corresponding to homogenous linear impulsive periodic system are shown. This allows us to apply Horn's fixed-point theorem to prove the existence of -periodic PC-mild solutions when PC-mild solutions are ultimate bounded. This extends the study on periodic solutions of periodic system without impulse to periodic system with impulse on general Banach spaces. At last, an example is given for demonstration.

  10. Mean-periodic functions

    Directory of Open Access Journals (Sweden)

    Carlos A. Berenstein

    1980-01-01

    Full Text Available We show that any mean-periodic function f can be represented in terms of exponential-polynomial solutions of the same convolution equation f satisfies, i.e., u∗f=0(μ∈E′(ℝn. This extends to n-variables the work of L. Schwartz on mean-periodicity and also extends L. Ehrenpreis' work on partial differential equations with constant coefficients to arbitrary convolutors. We also answer a number of open questions about mean-periodic functions of one variable. The basic ingredient is our work on interpolation by entire functions in one and several complex variables.

  11. Method of constructing reactor buildings

    International Nuclear Information System (INIS)

    Hyuga, Takenori; Nagai, Fumio; Akutsu, Masayoshi.

    1985-01-01

    Purpose: To shorten the construction period for LMFBR type reactors, as well as smoothly introduce high pressure steams generated in concretes upon loss of coolant accidents to the outside of the system. Method: After disposing a liner plate as a chamber lining of reactor buildings, heat insulation materials having steam discharge channels at the outer surface are attached to the outside of the liner plate and, further, an organic films are disposed to the outside of the heat insulation materials. Then, concretes are spiked to the outside of the organic films using the liner plate and the heat insulation material as the mold for concretes. In this way, the construction period can be shortened by utilizing the liner plate and the heat insulation materials as the mold for concretes, as well as steams at high temperature resulted in the concretes upon loss of coolant accidents can smoothly be discharged to the outside of the system. (Moriyama, K.)

  12. Painful periods (dysmenorrhea) (image)

    Science.gov (United States)

    Primary dysmenorrhea is a normal cramping of the lower abdomen caused by hormone-induced uterine contractions before the period. Secondary dysmenorrhea may be caused by abnormal conditions such as ...

  13. Vaginal bleeding between periods

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003156.htm Vaginal bleeding between periods To use the sharing features ... this page, please enable JavaScript. This article discusses vaginal bleeding that occurs between a woman's monthly menstrual ...

  14. Super periodic potential

    Science.gov (United States)

    Hasan, Mohammd; Mandal, Bhabani Prasad

    2018-04-01

    In this paper we introduce the concept of super periodic potential (SPP) of arbitrary order n, n ∈I+, in one dimension. General theory of wave propagation through SPP of order n is presented and the reflection and transmission coefficients are derived in their closed analytical form by transfer matrix formulation. We present scattering features of super periodic rectangular potential and super periodic delta potential as special cases of SPP. It is found that the symmetric self-similarity is the special case of super periodicity. Thus by identifying a symmetric fractal potential as special cases of SPP, one can obtain the tunnelling amplitude for a particle from such fractal potential. By using the formalism of SPP we obtain the close form expression of tunnelling amplitude of a particle for general Cantor and Smith-Volterra-Cantor potentials.

  15. Establishing contract periods

    International Nuclear Information System (INIS)

    Huffman, F.C.

    1978-01-01

    The lead time for executing the Adjustable Fixed-Commitment (AFC) contract and exceptions which may be considered are discussed. The initial delivery period is also discussed. Delays, deferrals, and schedule adjustment charges are finally considered

  16. The Periodic Table CD.

    Science.gov (United States)

    Banks, Alton J.; Holmes, Jon L.

    1995-01-01

    Describes the characteristics of the digitized version of The Periodic Table Videodisc. Provides details about the organization of information and access to the data via Macintosh and Windows computers. (DDR)

  17. Setting the Periodic Table.

    Science.gov (United States)

    Saturnelli, Annette

    1985-01-01

    Examines problems resulting from different forms of the periodic table, indicating that New York State schools use a form reflecting the International Union of Pure and Applied Chemistry's 1984 recommendations. Other formats used and reasons for standardization are discussed. (DH)

  18. Supersymmetrically transformed periodic potentials

    OpenAIRE

    C, David J. Fernandez

    2003-01-01

    The higher order supersymmetric partners of a stationary periodic potential are studied. The transformation functions associated to the band edges do not change the spectral structure. However, when the transformation is implemented for factorization energies inside of the forbidden bands, the final potential will have again the initial band structure but it can have bound states encrusted into the gaps, giving place to localized periodicity defects.

  19. Thyrotoxic periodic paralysis

    OpenAIRE

    Rojith Karandode Balakrishnan; Suresh Rama Chandran; Geetha Thirumalnesan; Nedumaran Doraisamy

    2011-01-01

    This article aims at highlighting the importance of suspecting thyrotoxicosis in cases of recurrent periodic flaccid paralysis; especially in Asian men to facilitate early diagnosis of the former condition. A case report of a 28 year old male patient with recurrent periodic flaccid paralysis has been presented. Hypokalemia secondary to thyrotoxicosis was diagnosed as the cause of the paralysis. The patient was given oral potassium intervention over 24 hours. The patient showed complete recove...

  20. The development and validation of a shorter version of the Canadian Health Care Evaluation Project Questionnaire (CANHELP Lite): a novel tool to measure patient and family satisfaction with end-of-life care.

    Science.gov (United States)

    Heyland, Daren K; Jiang, Xuran; Day, Andrew G; Cohen, S Robin

    2013-08-01

    The recently developed Canadian Health Care Evaluation Project (CANHELP) questionnaire, which can be used to assess both patient and family satisfaction with end-of-life care, takes 40-60 minutes to complete. The length of the interview may limit its uptake and clinical utility; a shorter version would make its use more feasible. The purpose of this study was to develop and validate a shorter version of the CANHELP questionnaire. Data were collected using a cross-sectional survey of patients with advanced medical diseases and their family members. Participants completed the long version of CANHELP, a global rating of satisfaction with care (GRS), the FAMCARE scale (family members only), and a quality-of-life (QOL) questionnaire. We reduced the items on the long version based on their relationship to the GRS, the frequency of missing data, the distribution of responses, the redundancy of the items, and focus groups with frontline users. With the remaining items, we assessed internal consistency using Cronbach's alpha, and evaluated construct validity by describing the correlation of the new CANHELP Lite with the full version of CANHELP, GRS, FAMCARE, and the QOL questionnaire scores. A total of 363 patients and 193 family members participated in this study. The patient version was reduced from 37 items to 20 items and the caregiver version was reduced from 38 items to 21 items. Cronbach's alphas ranged from 0.68 to 0.93 for all domains of both the patient and caregiver questionnaires. We observed a high degree of correlation between CANHELP Lite domains and overall scores and the same domains and overall scores for the full version of CANHELP. In addition, we observed moderate to strong correlation between the CANHELP Lite overall satisfaction scores and the GRS questions. There was moderate correlation between the overall family member CANHELP Lite score and overall FAMCARE score (r = 0.45) and this was similar to the correlation between the full version of

  1. Induction of a shorter compression phase is correlated with a deeper chest compression during metronome-guided cardiopulmonary resuscitation: a manikin study.

    Science.gov (United States)

    Chung, Tae Nyoung; Bae, Jinkun; Kim, Eui Chung; Cho, Yun Kyung; You, Je Sung; Choi, Sung Wook; Kim, Ok Jun

    2013-07-01

    Recent studies have shown that there may be an interaction between duty cycle and other factors related to the quality of chest compression. Duty cycle represents the fraction of compression phase. We aimed to investigate the effect of shorter compression phase on average chest compression depth during metronome-guided cardiopulmonary resuscitation. Senior medical students performed 12 sets of chest compressions following the guiding sounds, with three down-stroke patterns (normal, fast and very fast) and four rates (80, 100, 120 and 140 compressions/min) in random sequence. Repeated-measures analysis of variance was used to compare the average chest compression depth and duty cycle among the trials. The average chest compression depth increased and the duty cycle decreased in a linear fashion as the down-stroke pattern shifted from normal to very fast (pmetronome-guided cardiopulmonary resuscitation.

  2. High Numbers of Stromal Cancer-Associated Fibroblasts Are Associated With a Shorter Survival Time in Cats With Oral Squamous Cell Carcinoma.

    Science.gov (United States)

    Klobukowska, H J; Munday, J S

    2016-11-01

    Cancer-associated fibroblasts (CAFs) are fibroblastic cells that express α-smooth muscle actin and have been identified in the stroma of numerous epithelial tumors. The presence of CAFs within the tumor stroma has been associated with a poorer prognosis in some human cancers, including oral squamous cell carcinomas (SCCs). Cats frequently develop oral SCCs, and although these are generally highly aggressive neoplasms, there is currently a lack of prognostic markers for these tumors. The authors investigated the prognostic value of the presence of CAFs within the stroma of oral SCC biopsy specimens from 47 cats. In addition, several epidemiologic, clinical, and histologic variables were also assessed for prognostic significance. A CAF-positive stroma was identified in 35 of 47 SCCs (74.5%), and the median survival time (ST) of cats with CAF-positive SCCs (35 days) was significantly shorter than that of cats with CAF-negative SCCs (48.5 days) (P = .031). ST was also associated with the location of the primary tumor (P = .0018): the median ST for oropharyngeal SCCs (179 days) was significantly longer than for maxillary (43.5 days; P = .047), mandibular (42 days; P = .022), and sublingual SCCs (22.5 days; P = .0005). The median ST of sublingual SCCs was also shorter compared with maxillary SCCs (P = .0017). Furthermore, a significant association was identified between site and the presence of stromal CAFs (P = .025). On the basis of this retrospective study, evaluating the tumor stroma for CAFs in feline oral SCC biopsy specimens may be of potential prognostic value. © The Author(s) 2016.

  3. Self-produced Time Intervals Are Perceived as More Variable and/or Shorter Depending on Temporal Context in Subsecond and Suprasecond Ranges

    Directory of Open Access Journals (Sweden)

    Keita eMitani

    2016-06-01

    Full Text Available The processing of time intervals is fundamental for sensorimotor and cognitive functions. Perceptual and motor timing are often performed concurrently (e.g., playing a musical instrument. Although previous studies have shown the influence of body movements on time perception, how we perceive self-produced time intervals has remained unclear. Furthermore, it has been suggested that the timing mechanisms are distinct for the sub- and suprasecond ranges. Here, we compared perceptual performances for self-produced and passively presented time intervals in random contexts (i.e., multiple target intervals presented in a session across the sub- and suprasecond ranges (Experiment 1 and within the sub- (Experiment 2 and suprasecond (Experiment 3 ranges, and in a constant context (i.e., a single target interval presented in a session in the sub- and suprasecond ranges (Experiment 4. We show that self-produced time intervals were perceived as shorter and more variable across the sub- and suprasecond ranges and within the suprasecond range but not within the subsecond range in a random context. In a constant context, the self-produced time intervals were perceived as more variable in the suprasecond range but not in the subsecond range. The impairing effects indicate that motor timing interferes with perceptual timing. The dependence of impairment on temporal contexts suggests multiple timing mechanisms for the subsecond and suprasecond ranges. In addition, violation of the scalar property (i.e., a constant variability to target interval ratio was observed between the sub- and suprasecond ranges. The violation was clearer for motor timing than for perceptual timing. This suggests that the multiple timing mechanisms for the sub- and suprasecond ranges overlap more for perception than for motor. Moreover, the central tendency effect (i.e., where shorter base intervals are overestimated and longer base intervals are underestimated disappeared with subsecond

  4. Effect of Group Exercising and Adjusting the Brace at Shorter Intervals on Cobb Angle and Quality of Life of Patients with Idiopathic Scoliosis

    Directory of Open Access Journals (Sweden)

    Zahra Hedayati

    2016-01-01

    Full Text Available Objective: Bracing along with exercising is the most effective protocol in patients with idiopathic scoliosis which have Cobb angles of 25 to 45 degrees. However, since the psychological aspects of scoliosis treatment may affect the quality of life, and the exact time for adjusting the pads of Milwaukee brace is unknown; Therefore the aim of this study was evaluating the effect of exercising in a group, with adjusting the brace in shorter intervals, in compare to routine protocol, in the treatment of idiopathic scoliosis. Matterials & Methods: Thirty-four patients with idiopathic scoliosis which had Cobb angles of 50 to 15 degrees were included in this study and were divided into experimental and control groups. The patients of two groups participated in an eleven-week treatment program, differ between the two groups. Quality of life scores of both groups were evaluated before and after intervention using SRS-22 questionnaire, as well as scoliosis angles before and after the intervention according to the primary and secondary radiographic X-rays. Results: Statistical analysis was performed using Paired T-Test in each group, and Independent T-Test between the two groups before and after treatment. The severity of scoliosis curvature and satisfaction domain of the experimental group was reduced significantly in compared with the control group, after intervention (P=0.04. Moreover in the case of  the quality of life in patients with Cobb angles less than 30 degrees, compared with patients with Cobb angles greater than 31 degrees, in the domains of self-image, satisfaction, and total score, the difference was significant (P<0.05. Conclusion: Adjusting the brace at shorter intervals along with exercising as a group, during the eleven weeks of treatment, has increased satisfaction and reduced the scoliosis Cobb angles of patients.

  5. Application of value engineering technique in construction project

    International Nuclear Information System (INIS)

    Chen Changbing

    2003-01-01

    The author introduces how to apply the theories and methods of the value engineering in construction project. In the construction of a test device of the thermal hydrodynamic process, the authors have greatly reduced the construction cost and shortened the construction period by using the value engineering analyzing method. The application of value engineering in the project management is innovative. This practice indicates that the value engineering is important in many construction projects

  6. Periodic table of elements

    International Nuclear Information System (INIS)

    Fluck, E.; Heumann, K.G.

    1985-01-01

    Following a recommendation by the International Union for Pure and Applied Chemistry (IUPAC), the groups of the periodic table shall be numbered from 1 to 18, instead of I to VIII as before. The recommendations has been approved of by the Committee on Nomenclature of the American Chemical Society. The new system abandons the distinction between main groups (a) and auxiliary groups (b), which in the past frequently has been the reason for misunderstandings between European and American chemists, due to different handling. The publishing house VCH Verlagsgesellschaft recently produced a new periodic table that shows the old and the new numbering system together at a glance, so that chemists will have time to get familiar with the new system. In addition the new periodic table represents an extensive data compilation arranged by elements. The front page lists the chemical properties of elements, the back page their physical properties. (orig./EF) [de

  7. Thyrotoxic periodic paralysis

    Directory of Open Access Journals (Sweden)

    Rojith Karandode Balakrishnan

    2011-01-01

    Full Text Available This article aims at highlighting the importance of suspecting thyrotoxicosis in cases of recurrent periodic flaccid paralysis; especially in Asian men to facilitate early diagnosis of the former condition. A case report of a 28 year old male patient with recurrent periodic flaccid paralysis has been presented. Hypokalemia secondary to thyrotoxicosis was diagnosed as the cause of the paralysis. The patient was given oral potassium intervention over 24 hours. The patient showed complete recovery after the medical intervention and was discharged after 24 hours with no residual paralysis. Thyrotoxic periodic paralysis (TPP is a complication of thyrotoxicosis, more common amongst males in Asia. It presents as acute flaccid paralysis in a case of hyperthyroidism with associated hypokalemia. The features of thyrotoxicosis may be subtle or absent. Thus, in cases of recurrent or acute flaccid muscle paralysis, it is important to consider thyrotoxicosis as one of the possible causes, and take measures accordingly.

  8. The power of the kashrut: older but shorter. The impact of religious nutritional and hygienic rules on stature and life expectancy of Jewish conscripts in the early 19th century.

    Science.gov (United States)

    Tassenaar, V; Karel, E H

    2016-06-01

    We test the impact of several demographic, economic and social factors on stature in an early nineteenth century environment. We use a database of conscripts from the period 1818-1860 of a rural province in The Netherlands (Drenthe). This area had a rather high biological standard of living. This database of 413 conscripts contains information about family structure, family rank order, height, tax income, occupation and age of death. Conscripts came from two communities: one from a particular village (Oosterhesselen) and the other was Jewish conscripts that came from the countryside of the province. Our statistical analysis shows a positive significant relationship between family size and height, which confirms the resource dilution theory. Remarkably, the sign of the relation between family size and life expectancy is inverse. Other factors such as the potato crisis and income had the expected effect on conscript heights. The community effect was strong. Jewish conscripts were much shorter than their counterparts. Access to nutrition, the specific food laws and other factors can explain this difference. An increasing sibship size had a negative impact on body height but positive effects on life expectancy when adulthood was reached. Specifically for the Jewish community was the positive effect of the death of the father on conscript height. The mechanisms behind this phenomenon are unclear and open for further research.

  9. Periodically poled silicon

    Science.gov (United States)

    Hon, Nick K.; Tsia, Kevin K.; Solli, Daniel R.; Khurgin, Jacob B.; Jalali, Bahram

    2010-02-01

    Bulk centrosymmetric silicon lacks second-order optical nonlinearity χ(2) - a foundational component of nonlinear optics. Here, we propose a new class of photonic device which enables χ(2) as well as quasi-phase matching based on periodic stress fields in silicon - periodically-poled silicon (PePSi). This concept adds the periodic poling capability to silicon photonics, and allows the excellent crystal quality and advanced manufacturing capabilities of silicon to be harnessed for devices based on χ(2)) effects. The concept can also be simply achieved by having periodic arrangement of stressed thin films along a silicon waveguide. As an example of the utility, we present simulations showing that mid-wave infrared radiation can be efficiently generated through difference frequency generation from near-infrared with a conversion efficiency of 50% based on χ(2) values measurements for strained silicon reported in the literature [Jacobson et al. Nature 441, 199 (2006)]. The use of PePSi for frequency conversion can also be extended to terahertz generation. With integrated piezoelectric material, dynamically control of χ(2)nonlinearity in PePSi waveguide may also be achieved. The successful realization of PePSi based devices depends on the strength of the stress induced χ(2) in silicon. Presently, there exists a significant discrepancy in the literature between the theoretical and experimentally measured values. We present a simple theoretical model that produces result consistent with prior theoretical works and use this model to identify possible reasons for this discrepancy.

  10. Hereditary periodic fever syndromes

    NARCIS (Netherlands)

    McDermott, MF; Frenkel, J

    Hereditary periodic fever syndromes are defined by recurrent attacks of generalised inflammation for which no infectious or auto-immune cause can be identified. For most of these disorders, the molecular basis has recently been elucidated. This has opened the prospect of novel therapeutic

  11. Almost periodic Schroedinger operators

    International Nuclear Information System (INIS)

    Bellissard, J.; Lima, R.

    1984-01-01

    These lectures are devoted to recent developments in the theory of almost-periodic Schroedinger Operators. We specially describe the algebraic point of view, with applications to gap-labelling theorems. Particular models are also presented which exhibit various spectral properties. (orig.)

  12. Astrophysical implications of periodicity

    International Nuclear Information System (INIS)

    Muller, R.A.

    1988-01-01

    Two remarkable discoveries of the last decade have profound implications for astrophysics and for geophysics. These are the discovery by Alvarez et al., that certain mass extinctions are caused by the impact on the earth of a large asteroid or comet, and the discovery by Raup and Sepkoski that such extinctions are periodic, with a cycle time of 26 to 30 million years. The validity of both of these discoveries is assumed and the implications are examined. Most of the phenomena described depend not on periodicity, but just on the weaker assumption that the impacts on the earth take place primarily in showers. Proposed explanations for the periodicity include galactic oscillations, the Planet X model, and the possibility of Nemesis, a solar companion star. These hypotheses are critically examined. Results of the search for the solar companion are reported. The Deccan flood basalts of India have been proposed as the impact site for the Cretaceous impact, but this hypotheisis is in contradiction with the conclusion of Courtillot et al., that the magma flow began during a period of normal magnetic field. A possible resolution of this contradiction is proposed

  13. Periodic Table of Students.

    Science.gov (United States)

    Johnson, Mike

    1998-01-01

    Presents an exercise in which an eighth-grade science teacher decorated the classroom with a periodic table of students. Student photographs were arranged according to similarities into vertical columns. Students were each assigned an atomic number according to their placement in the table. The table is then used to teach students about…

  14. A Modern Periodic Table.

    Science.gov (United States)

    Herrenden-Harker, B. D.

    1997-01-01

    Presents a modern Periodic Table based on the electron distribution in the outermost shell and the order of filling of the sublevels within the shells. Enables a student to read off directly the electronic configuration of the element and the order in which filling occurs. (JRH)

  15. Construction dust amelioration techniques.

    Science.gov (United States)

    2012-04-01

    Dust produced on seasonal road construction sites in Alaska is both a traffic safety and environmental concern. Dust emanating from : unpaved road surfaces during construction severely reduces visibility and impacts stopping sight distance, and contr...

  16. Improving concrete overlay construction.

    Science.gov (United States)

    2010-03-01

    Several road construction projects involving concrete overlays at the state and county levels in Iowa in 2009 were studied for : construction techniques and methods. The projects that were evaluated consisted of sites in four Iowa counties: Osceola, ...

  17. Construction project management handbook.

    Science.gov (United States)

    2012-03-01

    The purpose of the FTA Construction Project Management Handbook is to provide guidelines for use by public transit agencies (Agen-cies) undertaking substantial construction projects, either for the first time or with little prior experience with cons...

  18. Construction Sector (NAICS 23)

    Science.gov (United States)

    Find environmental regulatory information for the construction sector, including the construction of buildings or engineering projects. This includes RCRA information for hazardous waste, refrigeration compliance, asbestos, effluent guidelines & lead laws

  19. Organizational Behaviour in Construction

    DEFF Research Database (Denmark)

    Kreiner, Kristian

    2013-01-01

    Review of: Organizational Behaviour in Construction / Anthony Walker (Wiley-Blackwell,2011 336 pp)......Review of: Organizational Behaviour in Construction / Anthony Walker (Wiley-Blackwell,2011 336 pp)...

  20. Validating MEDIQUAL Constructs

    Science.gov (United States)

    Lee, Sang-Gun; Min, Jae H.

    In this paper, we validate MEDIQUAL constructs through the different media users in help desk service. In previous research, only two end-users' constructs were used: assurance and responsiveness. In this paper, we extend MEDIQUAL constructs to include reliability, empathy, assurance, tangibles, and responsiveness, which are based on the SERVQUAL theory. The results suggest that: 1) five MEDIQUAL constructs are validated through the factor analysis. That is, importance of the constructs have relatively high correlations between measures of the same construct using different methods and low correlations between measures of the constructs that are expected to differ; and 2) five MEDIQUAL constructs are statistically significant on media users' satisfaction in help desk service by regression analysis.

  1. Rogue periodic waves of the modified KdV equation

    Science.gov (United States)

    Chen, Jinbing; Pelinovsky, Dmitry E.

    2018-05-01

    Rogue periodic waves stand for rogue waves on a periodic background. Two families of travelling periodic waves of the modified Korteweg–de Vries (mKdV) equation in the focusing case are expressed by the Jacobian elliptic functions dn and cn. By using one-fold and two-fold Darboux transformations of the travelling periodic waves, we construct new explicit solutions for the mKdV equation. Since the dn-periodic wave is modulationally stable with respect to long-wave perturbations, the new solution constructed from the dn-periodic wave is a nonlinear superposition of an algebraically decaying soliton and the dn-periodic wave. On the other hand, since the cn-periodic wave is modulationally unstable with respect to long-wave perturbations, the new solution constructed from the cn-periodic wave is a rogue wave on the cn-periodic background, which generalizes the classical rogue wave (the so-called Peregrine’s breather) of the nonlinear Schrödinger equation. We compute the magnification factor for the rogue cn-periodic wave of the mKdV equation and show that it remains constant for all amplitudes. As a by-product of our work, we find explicit expressions for the periodic eigenfunctions of the spectral problem associated with the dn and cn periodic waves of the mKdV equation.

  2. Heterotic string construction

    International Nuclear Information System (INIS)

    Schellekens, A.N.

    1989-01-01

    In this paper an elementary introduction to the principles of four-dimensional string construction will be given. Although the emphasis is on lattice constructions, almost all results have further, and often quite straightforward generalizations to other constructions. Since heterotic strings look phenomenologically more promising than type-II theories the authors only consider the former, although everything can easily be generalized to type-II theories. Some additional aspects of lattice constructions are discussed, and an extensive review can be found

  3. Safety in construction industry

    International Nuclear Information System (INIS)

    Khan, A.M.

    1979-01-01

    Causative factors of accidents in construction industry in the context of experience of construction work of the Rajasthan Atomic Power Project are enumerated. The aspect of accident cost - direct and indirect - is discussed briefly. Setting up of a safety set-up at construction sites is emphasized and principles which should guide the accident prevention programme are spelt out. (M.G.B.)

  4. Thyrotoxic periodic paralysis

    International Nuclear Information System (INIS)

    Ferreiro, J.E.; Arguelles, D.J.; Rams, H. Jr.

    1986-01-01

    A case of thyrotoxic periodic paralysis is reported in a Hispanic man with an unusual recurrence six weeks after radioactive iodine treatment. Thyrotoxic periodic paralysis has now been well characterized in the literature: it occurs primarily in Orientals with an overwhelming male preponderance and a higher association of specific HLA antigens. Clinical manifestations include onset after high carbohydrate ingestion or heavy exertion, with progressive symmetric weakness leading to flaccid paralysis of the extremities and other muscle groups, lasting several hours. If hypokalemia is present, potassium administration may help abort the attack. Although propranolol can be efficacious in preventing further episodes, the only definitive treatment is establishing a euthyroid state. The pathophysiology is still controversial, but reflects altered potassium and calcium dynamics as well as certain morphologic characteristics within the muscle unit itself

  5. Do Dysphagic Patients with an Absent Pharyngeal Swallow Have a Shorter Survival than Dysphagic Patients with Pharyngeal Swallow? Prognostic Importance of a Therapeutic Videoradiographic Swallowing Study (TVSS)

    International Nuclear Information System (INIS)

    Buelow, M.; Olsson, R.; Ekberg, O.

    2005-01-01

    Purpose: To study survival in two groups of dysphagic patients - one group unable to elicit the pharyngeal stage of swallow (APS) and another group with pharyngeal swallow (WPS) - and to compare recommendations regarding nutrition and therapeutic strategies based on the therapeutic swallowing study. Material and Methods: In this retrospective study, the records of dysphagic patients who have undergone a therapeutic videoradiographic swallowing study (TVSS) were reviewed. Forty patients without pharyngeal swallow were matched for age and gender with 40 patients with pharyngeal swallow; altogether 80 patients were included in the study. Survival was registered at 3, 12, and 72 months after the TVSS. Results: In this study, the APS group had a significantly shorter survival time compared to the WPS group when followed-up at 12 months. In the APS group, most patients (37.5% (15/40)) died within the 3 months after TVSS. At 72 months, 62.5% (25/40) of the patients in the APS group had died. In the WPS group, 5% (2/40) had died within 3 months and 47.4% (19/40) after 12 months. At 72 months, 52.5% (21/40) of the patients in the WPS group had died. Regarding nutritional and therapeutic recommendations based on TVSS, 34/40 in the APS group were recommended no oral intake. Eighteen naso-gastric tubes were placed directly after TVSS. The therapeutic strategies recommended were head-positioning, thermal tactile stimulation, and tongue exercises (in 8 patients). In the WPS group, all patients were recommended oral intake. Diet modification was recommended in 29 patients. The therapeutic strategies recommended were head-positioning, thermal tactile stimulation, tongue exercises, supraglottic swallow, and effortful swallow (in 24 patients). Conclusion: Patients unable to elicit the pharyngeal stage of swallow had a shorter survival time than patients with pharyngeal swallow, probably due to a more severe underlying disease. Tube feeding was more frequent in the APS group. Fewer

  6. The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer

    Directory of Open Access Journals (Sweden)

    Lane Denis

    2010-01-01

    associated with shorter disease-free interval. Conclusions The prosurvival activity of ascites against TRAIL is associated with shorter disease-free interval, which may be explained, at least in part, by ascites-induced cisplatin/paclitaxel resistance. Our findings suggest that ascites may contain prosurvival factors that protect against TRAIL and chemotherapy and consequently affect disease progression.

  7. Progesterone-releasing devices for cattle estrus induction and synchronization: Device optimization to anticipate shorter treatment durations and new device developments.

    Science.gov (United States)

    de Graaff, W; Grimard, B

    2018-05-01

    Synchronization programs using progesterone-releasing intravaginal devices that allow for fixed time artificial insemination are still finding increasing application in bovine reproduction. This practice is useful for rationalizing livestock management because an increased number of cows can be inseminated in one session without the need for estrus detection. Although much of the innovation related to the design and development of intravaginal devices for use in cattle took place in the previous century, progress in understanding the physiology of the bovine estrous cycle resulted in shorter treatment durations, a trend which is still continuing. In this competitive market, with little functional differentiation between the existing devices, the shorter treatment duration prompted for optimization of the progesterone content in the device, as the cost of the drug significantly contributes to the price per unit. For CIDR ® a reduction of the progesterone content of about 30 per cent was realized. Price reduction remained an important target for further device development. Next to reduction of progesterone content, cheaper and easier to process materials like polyethylene vinyl acetate (EVA) copolymers have been explored to replace the commonly used silicone elastomers. The reengineering effort of CIDR ® demonstrated that knowledge of release kinetics and insight into gradual depletion patterns in the device is critical for optimization of drug content without compromising performance (blood levels). More recent publications related to the use of alternative polymers like EVA and polyisoprene (IP) indicated encouraging results regarding further reduction of progesterone content. The use of EVA seems most promising, because it is in principle a low-cost polymer available in many grades and this thermoplastic polymer can be processed easily by means of commonly used techniques like injection molding and extrusion. The use of thermoplastic polymers, however, requires

  8. Time-Varying Periodicity in Intraday Volatility

    DEFF Research Database (Denmark)

    Andersen, Torben Gustav; Thyrsgaard, Martin; Todorov, Viktor

    We develop a nonparametric test for deciding whether return volatility exhibits time-varying intraday periodicity using a long time-series of high-frequency data. Our null hypothesis, commonly adopted in work on volatility modeling, is that volatility follows a stationary process combined...... with a constant time-of-day periodic component. We first construct time-of-day volatility estimates and studentize the high-frequency returns with these periodic components. If the intraday volatility periodicity is invariant over time, then the distribution of the studentized returns should be identical across...... with estimating volatility moments through their sample counterparts. Critical values are computed via easy-to-implement simulation. In an empirical application to S&P 500 index returns, we find strong evidence for variation in the intraday volatility pattern driven in part by the current level of volatility...

  9. A generalized, periodic nonlinearity-reduced interferometer for straightness measurements

    International Nuclear Information System (INIS)

    Wu Chienming

    2008-01-01

    Periodic nonlinearity is a systematic error limiting the accuracy of displacement measurements at the nanometer level. However, an interferometer with a displacement measurement accuracy of less than 1 nm is required in nanometrology and in fundamental scientific research. To meet this requirement, a generalized, periodic nonlinearity-reduced interferometer, based on three construction principles has been developed for straightness measurements. These three construction principles have resulted in an interferometer with a highly stable design with reduced periodic nonlinearity. Verifications by a straightness interferometer have demonstrated that the periodic nonlinearity was less than 40 pm. The results also demonstrate that the interferometer design is capable of subnanometer accuracy and is useful in nanometrology

  10. Distinct functions of Period2 and Period3 in the mouse circadian system revealed by in vitro analysis.

    Directory of Open Access Journals (Sweden)

    Julie S Pendergast

    2010-01-01

    Full Text Available The mammalian circadian system, which is composed of a master pacemaker in the suprachiasmatic nuclei (SCN as well as other oscillators in the brain and peripheral tissues, controls daily rhythms of behavior and physiology. Lesions of the SCN abolish circadian rhythms of locomotor activity and transplants of fetal SCN tissue restore rhythmic behavior with the periodicity of the donor's genotype, suggesting that the SCN determines the period of the circadian behavioral rhythm. According to the model of timekeeping in the SCN, the Period (Per genes are important elements of the transcriptional/translational feedback loops that generate the endogenous circadian rhythm. Previous studies have investigated the functions of the Per genes by examining locomotor activity in mice lacking functional PERIOD proteins. Variable behavioral phenotypes were observed depending on the line and genetic background of the mice. In the current study we assessed both wheel-running activity and Per1-promoter-driven luciferase expression (Per1-luc in cultured SCN, pituitary, and lung explants from Per2(-/- and Per3(-/- mice congenic with the C57BL/6J strain. We found that the Per2(-/- phenotype is enhanced in vitro compared to in vivo, such that the period of Per1-luc expression in Per2(-/- SCN explants is 1.5 hours shorter than in Per2+/+ SCN, while the free-running period of wheel-running activity is only 11 minutes shorter in Per2(-/- compared to Per2+/+ mice. In contrast, circadian rhythms in SCN explants from Per3(-/- mice do not differ from Per3+/+ mice. Instead, the period and phase of Per1-luc expression are significantly altered in Per3(-/- pituitary and lung explants compared to Per3+/+ mice. Taken together these data suggest that the function of each Per gene may differ between tissues. Per2 appears to be important for period determination in the SCN, while Per3 participates in timekeeping in the pituitary and lung.

  11. Sustainable construction: construction and demolition waste reconsidered.

    Science.gov (United States)

    del Río Merino, Mercedes; Izquierdo Gracia, Pilar; Weis Azevedo, Isabel Salto

    2010-02-01

    Construction activity in Europe has increased substantially in the past decade. Likewise, there has also been a commensurate rise in the generation of construction and demolition waste (C&DW). This, together with the fact that in many European countries the rate of recycling and reuse of C&DW is still quite low has engendered a serious environmental problem and a motivation to develop strategies and management plans to solve it. Due to its composition, there is a significant potential to reuse and/or recycle C&DW, and thereby, contribute to improving the sustainability of construction and development, but practical procedures are not yet widely known or practiced in the construction industry. This article (a) summarizes the different applications that are presently practiced to optimize the recovery and/or application of C&DW for reuse, and (b) proposes various measures and strategies to improve the processing of this waste. The authors suggest that to enhance environmental effectiveness, a conscious and comprehensive C&DW management plan should be implemented in each jurisdiction. More precisely, this study presents a holistic approach towards C&DW management, through which environmental benefits can be achieved through the application of new construction methods that can contribute to sustainable growth.

  12. TPX tokamak construction management

    International Nuclear Information System (INIS)

    Knutson, D.; Kungl, D.; Seidel, P.; Halfast, C.

    1995-01-01

    A construction management contract normally involves the acquisition of a construction management firm to assist in the design, planning, budget conformance, and coordination of the construction effort. In addition the construction management firm acts as an agent in the awarding of lower tier contracts. The TPX Tokamak Construction Management (TCM) approach differs in that the construction management firm is also directly responsible for the assembly and installation of the tokamak including the design and fabrication of all tooling required for assembly. The Systems Integration Support (SIS) contractor is responsible for the architect-engineering design of ancillary systems, such as heating and cooling, buildings, modifications and site improvements, and a variety of electrical requirements, including switchyards and >4kV power distribution. The TCM will be responsible for the procurement of materials and the installation of the ancillary systems, which can either be performed directly by the TCM or subcontracted to a lower tier subcontractor. Assurance that the TPX tokamak is properly assembled and ready for operation when turned over to the operations team is the primary focus of the construction management effort. To accomplish this a disciplined constructability program will be instituted. The constructability effort will involve the effective and timely integration of construction expertise into the planning, component design, and field operations. Although individual component design groups will provide liaison during the machine assembly operations, the construction management team is responsible for assembly

  13. Towards green construction

    International Nuclear Information System (INIS)

    Bajracharya, Bijaya B.; Shrestha, Prasanna M.

    2000-01-01

    Sustainability is the key to any development works. In the operation phase, hydro power is the most sustainable form of energy. However construction activities for the same power station are usually far from being green. The popular myth is that construction activity converts green into grey. Despite this popular myth, construction of a hydro power project in Nepal has made the project area greener than earlier during the construction phase itself. Choice of construction technology, appropriate level of environmental impact assessment, monitoring of environmental parameters along side the construction progress followed by mitigation at the right time; launching community development programmes side by side, having environmental specification in contractual documents and self-reliance to fulfill environmental obligations by contractors itself are the key factors in the environmental management within the construction activities. The main conclusions in the paper is the need to change the way to think about the project constraints

  14. How engineering facilitates construction

    International Nuclear Information System (INIS)

    Bailey, D.T.

    1976-01-01

    During a recent survey, construction personnel at jobsites were asked, ''what are the ten most unwanted construction problems.'' One reoccurring answer was design/construction incompatibility. In fact, many designs were impractical from a construction point of view. The reasons for this problem can be identified: Once construction begins, engineering is under intense pressure to issue new drawings to allow work to progress according to schedule. Other reasons may be the relative inexperience of the design personnel in construction, changes in design criteria and delays in receipt of supplier or client information. A description is presented of ways to solve this problem by obtaining construction expertise and input into the various phases and products of the engineering work

  15. On Helmholtz Problem for Plane Periodical Structures

    International Nuclear Information System (INIS)

    Akishin, P.G.; Vinitskij, S.I.

    1994-01-01

    The plane Helmholtz problem of the periodical disc structures with the phase shifts conditions of the solutions along the basis lattice vectors and the Dirichlet conditions on the basic boundaries is considered. The Green function satisfying the quasi periodical conditions on the lattice is constructed. The Helmholtz problem is reduced to the boundary integral equations for the simple layer potentials of this Green function. The methods of the discretization of the arising integral equations are proposed. The procedures of calculation of the matrix elements are discussed. The reality of the spectral parameter of the nonlinear continuous and discretized problems is shown. 8 refs., 2 figs

  16. Construction industry accidents in Spain.

    Science.gov (United States)

    Camino López, Miguel A; Ritzel, Dale O; Fontaneda, Ignacio; González Alcantara, Oscar J

    2008-01-01

    This paper analyzed industrial accidents that take place on construction sites and their severity. Eighteen variables were studied. We analyzed the influence of each of these with respect to the severity and fatality of the accident. This descriptive analysis was grounded in 1,630,452 accidents, representing the total number of accidents suffered by workers in the construction sector in Spain over the period 1990-2000. It was shown that age, type of contract, time of accident, length of service in the company, company size, day of the week, and the remainder of the variables under analysis influenced the seriousness of the accident. IMPACT ON INJURY PREVENTION: The results obtained show that different training was needed, depending on the severity of accidents, for different age, length of service in the company, organization of work, and time when workers work. The research provides an insight to the likely causes of construction injuries in Spain. As a result of the analysis, industries and governmental agencies in Spain can start to provide appropriate strategies and training to the construction workers.

  17. Patients with Duchenne muscular dystrophy are significantly shorter than those with Becker muscular dystrophy, with the higher incidence of short stature in Dp71 mutated subgroup.

    Science.gov (United States)

    Matsumoto, Masaaki; Awano, Hiroyuki; Lee, Tomoko; Takeshima, Yasuhiro; Matsuo, Masafumi; Iijima, Kazumoto

    2017-11-01

    Duchenne and Becker muscular dystrophy (DMD/BMD) are caused by mutations in the dystrophin gene and are characterized by severe and mild progressive muscle wasting, respectively. Short stature has been reported as a feature of DMD in the Western hemisphere, but not yet confirmed in Orientals. Height of young BMD has not been fully characterized. Here, height of ambulant and steroid naive Japanese 179 DMD and 42 BMD patients between 4 and 10 years of age was retrospectively examined using height standard deviation score (SDS). The mean height SDS of DMD was -1.08 SD that was significantly smaller than normal (p < 0.001), indicating short stature of Japanese DMD. Furthermore, the mean height SDS of BMD was -0.27 SD, suggesting shorter stature than normal. Remarkably, the mean height SDS of DMD was significantly smaller than that of BMD (p < 0.0001). In DMD higher incidence of short stature (height SDS < -2.5 SD) was observed in Dp71 subgroup having mutations in dystrophin exons 63-79 than others having mutations in exons 1-62 (27.8% vs. 7.5%, p = 0.017). These suggested that height is influenced by dystrophin in not only DMD but also BMD and that dystrophin Dp71 has a role in height regulation. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Aiming for a shorter rheumatoid arthritis MRI protocol: can contrast-enhanced MRI replace T2 for the detection of bone marrow oedema?

    Energy Technology Data Exchange (ETDEWEB)

    Stomp, Wouter; Bloem, Johan L.; Reijnierse, Monique [Leiden University Medical Center, Department of Radiology, P.O. Box 9600, Leiden (Netherlands); Krabben, Annemarie; Heijde, Desiree van der; Huizinga, Tom W.J.; Helm-van Mil, Annette H.M. van der [Leiden University Medical Center, Department of Rheumatology, P.O. Box 9600, Leiden (Netherlands)

    2014-10-15

    To determine whether T1 post-gadolinium chelate images (T1Gd) can replace T2-weighted images (T2) for evaluating bone marrow oedema (BME), thereby allowing a shorter magnetic resonance imaging (MRI) protocol in rheumatoid arthritis (RA). In 179 early arthritis patients and 43 advanced RA patients, wrist and metacarpophalangeal joints were examined on a 1.5-T extremity MRI system with a standard protocol (coronal T1, T2 fat-saturated and coronal and axial T1 fat-saturated after Gd). BME was scored according to OMERACT RAMRIS by two observers with and without T2 images available. Agreement was assessed using intraclass correlation coefficients (ICCs) for semi-quantitative scores and test characteristics with T2 images as reference. Agreement between scores based on T2 and T1Gd images was excellent ICC (0.80-0.99). At bone level, sensitivity and specificity of BME on T1Gd compared to T2 were high for both patient groups and both readers (all ≥80 %). T1Gd and T2 images are equally suitable for evaluating BME. Because contrast is usually administered to assess (teno)synovitis, a short MRI protocol of T1 and T1Gd is sufficient in RA. (orig.)

  19. Disparate patterns of age-related changes in lipid peroxidation in long-lived naked mole-rats and shorter-lived mice.

    Science.gov (United States)

    Andziak, Blazej; Buffenstein, Rochelle

    2006-12-01

    A key tenet of the oxidative stress theory of aging is that levels of accrued oxidative damage increase with age. Differences in damage generation and accumulation therefore may underlie the natural variation in species longevity. We compared age-related profiles of whole-organism lipid peroxidation (urinary isoprostanes) and liver lipid damage (malondialdehyde) in long living naked mole-rats [maximum lifespan (MLS) > 28.3 years] and shorter-living CB6F1 hybrid mice (MLS approximately 3.5 years). In addition, we compared age-associated changes in liver non-heme iron to assess how intracellular conditions, which may modulate oxidative processes, are affected by aging. Surprisingly, even at a young age, concentrations of both markers of lipid peroxidation, as well as of iron, were at least twofold (P naked mole tats than in mice. This refutes the hypothesis that prolonged naked mole-rat longevity is due to superior protection against oxidative stress. The age-related profiles of all three parameters were distinctly species specific. Rates of lipid damage generation in mice were maintained throughout adulthood, while accrued damage in old animals was twice that of young mice. In naked mole-rats, urinary isoprostane excretion declined by half with age (P naked mole-rats is independent of oxidative stress parameters.

  20. Shorter Exciton Lifetimes via an External Heavy-Atom Effect: Alleviating the Effects of Bimolecular Processes in Organic Light-Emitting Diodes.

    Science.gov (United States)

    Einzinger, Markus; Zhu, Tianyu; de Silva, Piotr; Belger, Christian; Swager, Timothy M; Van Voorhis, Troy; Baldo, Marc A

    2017-10-01

    Multiexcited-state phenomena are believed to be the root cause of two exigent challenges in organic light-emitting diodes; namely, efficiency roll-off and degradation. The development of novel strategies to reduce exciton densities under heavy load is therefore highly desirable. Here, it is shown that triplet exciton lifetimes of thermally activated delayed-fluorescence-emitter molecules can be manipulated in the solid state by exploiting intermolecular interactions. The external heavy-atom effect of brominated host molecules leads to increased spin-orbit coupling, which in turn enhances intersystem crossing rates in the guest molecule. Wave function overlap between the host and the guest is confirmed by combined molecular dynamics and density functional theory calculations. Shorter triplet exciton lifetimes are observed, while high photoluminescence quantum yields and essentially unaltered emission spectra are maintained. A change in the intersystem crossing rate ratio due to increased dielectric constants leads to almost 50% lower triplet exciton densities in the emissive layer in the steady state and results in an improved onset of the photoluminescence quantum yield roll-off at high excitation densities. Efficient organic light-emitting diodes with better roll-off behavior based on these novel hosts are fabricated, demonstrating the suitability of this concept for real-world applications. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Aiming for a shorter rheumatoid arthritis MRI protocol: can contrast-enhanced MRI replace T2 for the detection of bone marrow oedema?

    International Nuclear Information System (INIS)

    Stomp, Wouter; Bloem, Johan L.; Reijnierse, Monique; Krabben, Annemarie; Heijde, Desiree van der; Huizinga, Tom W.J.; Helm-van Mil, Annette H.M. van der

    2014-01-01

    To determine whether T1 post-gadolinium chelate images (T1Gd) can replace T2-weighted images (T2) for evaluating bone marrow oedema (BME), thereby allowing a shorter magnetic resonance imaging (MRI) protocol in rheumatoid arthritis (RA). In 179 early arthritis patients and 43 advanced RA patients, wrist and metacarpophalangeal joints were examined on a 1.5-T extremity MRI system with a standard protocol (coronal T1, T2 fat-saturated and coronal and axial T1 fat-saturated after Gd). BME was scored according to OMERACT RAMRIS by two observers with and without T2 images available. Agreement was assessed using intraclass correlation coefficients (ICCs) for semi-quantitative scores and test characteristics with T2 images as reference. Agreement between scores based on T2 and T1Gd images was excellent ICC (0.80-0.99). At bone level, sensitivity and specificity of BME on T1Gd compared to T2 were high for both patient groups and both readers (all ≥80 %). T1Gd and T2 images are equally suitable for evaluating BME. Because contrast is usually administered to assess (teno)synovitis, a short MRI protocol of T1 and T1Gd is sufficient in RA. (orig.)

  2. Construction safety program for the National Ignition Facility

    International Nuclear Information System (INIS)

    Cerruti, S.J.

    1997-01-01

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and initial activation and operation of NIF at LLNL during the construction period of NIF

  3. Construction safety program for the National Ignition Facility

    International Nuclear Information System (INIS)

    Cerruti, S.J.

    1997-01-01

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and initial activation and operation of NIF at LLNL during the construction period of NIF. During this period, all workers are required to implement measures to create a universal awareness which promotes safe practice at the work site, and which will achieve NIF's management objectives in preventing accidents and illnesses. Construction safety for NIF is predicated on everyone performing their jobs in a manner which prevents job-related disabling injuries and illnesses. The CSP outlines the minimum environment, safety, and health (ES ampersand H) standards, LLNL policies and the Construction Industry Institute (CII) Zero Injury Techniques requirements that all workers at the NIF construction site shall adhere to during the construction period of NIF. It identifies the safety requirements which the NIF organizational Elements, construction contractors and construction subcontractors must include in their safety plans for the construction period of NIF, and presents safety protocols and guidelines which workers shall follow to assure a safe and healthful work environment. The CSP also identifies the ES ampersand H responsibilities of LLNL employees, non-LLNL employees, construction contractors, construction subcontractors, and various levels of management within the NIF Program at LLNL. In addition, the CSP contains the responsibilities and functions of ES ampersand H support organizations and administrative groups, and describes their interactions with the NIF Program

  4. Construction safety program for the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Cerruti, S.J.

    1997-06-26

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and initial activation and operation of NIF at LLNL during the construction period of NIF.

  5. Construction safety program for the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Cerruti, S.J.

    1997-01-01

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and initial activation and operation of NIF at LLNL during the construction period of NIF. During this period, all workers are required to implement measures to create a universal awareness which promotes safe practice at the work site, and which will achieve NIF`s management objectives in preventing accidents and illnesses. Construction safety for NIF is predicated on everyone performing their jobs in a manner which prevents job-related disabling injuries and illnesses. The CSP outlines the minimum environment, safety, and health (ES&H) standards, LLNL policies and the Construction Industry Institute (CII) Zero Injury Techniques requirements that all workers at the NIF construction site shall adhere to during the construction period of NIF. It identifies the safety requirements which the NIF organizational Elements, construction contractors and construction subcontractors must include in their safety plans for the construction period of NIF, and presents safety protocols and guidelines which workers shall follow to assure a safe and healthful work environment. The CSP also identifies the ES&H responsibilities of LLNL employees, non-LLNL employees, construction contractors, construction subcontractors, and various levels of management within the NIF Program at LLNL. In addition, the CSP contains the responsibilities and functions of ES&H support organizations and administrative groups, and describes their interactions with the NIF Program.

  6. Polysheroidal periodic functions

    International Nuclear Information System (INIS)

    Truskova, N.F.

    1985-01-01

    Separation of variables in the Helmholtz N-dimensional (N≥4) equation in polyspheroidal coordinate systems leads to the necessity of solving equations going over into equations for polyspheroidal periodic functions used for solving the two-centre problem in quantum mechanics, the three-body problem with Coulomb interaction, etc. For these functions the expansions are derived in terms of the Jacobi polynomials and Bessel functions. Their basic properties, asymptotics are considered. The algorithm of their computer calculations is developed. The results of numerical calculations are given

  7. Deciphering Periodic Methanol Masers

    Science.gov (United States)

    Stecklum, Bringfried; Caratti o Garatti, Alessio; Henning, Thomas; Hodapp, Klaus; Hopp, Ulrich; Kraus, Alex; Linz, Hendrik; Sanna, Alberto; Sobolev, Andrej; Wolf, Verena

    2018-05-01

    Impressive progress has been made in recent years on massive star formation, yet the involved high optical depths even at submm/mm wavelengths make it difficult to reveal its details. Recently, accretion bursts of massive YSOs have been identified to cause flares of Class II methanol masers (methanol masers for short) due to enhanced mid-IR pumping. This opens a new window to protostellar accretion variability, and implies that periodic methanol masers hint at cyclic accretion. Pinning down the cause of the periodicity requires joint IR and radio monitoring. We derived the first IR light curve of a periodic maser host from NEOWISE data. The source, G107.298+5.639, is an intermediate-mass YSO hosting methanol and water masers which flare every 34.5 days. Our recent joint K-band and radio observations yielded first but marginal evidence for a phase lag between the rise of IR and maser emission, respectively, and revealed that both NEOWISE and K-band light curves are strongly affected by the light echo from the ambient dust. Both the superior resolution of IRAC over NEOWISE and the longer wavelengths compared to our ground-based imaging are required to inhibit the distractive contamination by the light echo. Thus, we ask for IRAC monitoring of G107 to cover one flare cycle, in tandem with 100-m Effelsberg and 2-m Wendelstein radio and NIR observations to obtain the first high-quality synoptic measurements of this kind of sources. The IR-maser phase lag, the intrinsic shape of the IR light curves and their possible color variation during the cycle allow us to constrain models for the periodic maser excitation. Since methanol masers are signposts of intermediate-mass and massive YSOs, deciphering their variability offers a clue to the dynamics of the accretion-mediated growth of massive stars and their feedback onto the immediate natal environment. The Spitzer light curve of such a maser-hosting YSO would be a legacy science product of the mission.

  8. Calculation of the mean differential group delay of periodically spun, randomly birefringent fibers

    Science.gov (United States)

    Galtarossa, Andrea; Griggio, Paola; Pizzinat, Anna; Palmieri, Luca

    2002-05-01

    Spinning is one of the most effective and well-known ways to reduce polarization mode dispersion of optical fibers. In spite of the popularity of spinning, a detailed theory of spin effects is still lacking. We report an analytical expression for the mean differential group delay of a randomly birefringent spun fiber. The result holds for any periodic spin function with a period shorter than the fiber's beat length.

  9. Constructing Student Problems in Phylogenetic Tree Construction.

    Science.gov (United States)

    Brewer, Steven D.

    Evolution is often equated with natural selection and is taught from a primarily functional perspective while comparative and historical approaches, which are critical for developing an appreciation of the power of evolutionary theory, are often neglected. This report describes a study of expert problem-solving in phylogenetic tree construction.…

  10. A Production Model for Construction: A Theoretical Framework

    Directory of Open Access Journals (Sweden)

    Ricardo Antunes

    2015-03-01

    Full Text Available The building construction industry faces challenges, such as increasing project complexity and scope requirements, but shorter deadlines. Additionally, economic uncertainty and rising business competition with a subsequent decrease in profit margins for the industry demands the development of new approaches to construction management. However, the building construction sector relies on practices based on intuition and experience, overlooking the dynamics of its production system. Furthermore, researchers maintain that the construction industry has no history of the application of mathematical approaches to model and manage production. Much work has been carried out on how manufacturing practices apply to construction projects, mostly lean principles. Nevertheless, there has been little research to understand the fundamental mechanisms of production in construction. This study develops an in-depth literature review to examine the existing knowledge about production models and their characteristics in order to establish a foundation for dynamic production systems management in construction. As a result, a theoretical framework is proposed, which will be instrumental in the future development of mathematical production models aimed at predicting the performance and behaviour of dynamic project-based systems in construction.

  11. Summary of nuclear power plant construction

    International Nuclear Information System (INIS)

    Tamura, Saburo

    1973-01-01

    Various conditions for the construction of nuclear power plants in Japan without natural resources were investigated. Expansion of the sites of plants, change of reactor vessels, standardization of nuclear power plants, possiblity of the reduction of construction period, approaching of nuclear power plants to consuming cities, and group construction were studied. Evaluation points were safety and economy. Previous sites of nuclear power plants were mostly on plane ground or cut and enlarge sites. Proposals for underground or offshore plants have been made. The underground plants were made at several places in Europe, and the ocean plant is now approved in U.S.A. as a plant on a man-made island. Vessels for containing nuclear reactors are the last barriers to the leakage of radioactive substance. At the initial period, the vessels were made of steel, which were surrounded by shielding material. Those were dry well type containers. Then, vessel type changed to pressure-suppression type wet containers. Now, it tends to concrete (PC or RC) type containers. There is the policy on the standardization of nuclear power plants by U.S.A.E.C. in recent remarkable activity. The merit and effect of the standardization were studied, and are presented in this paper. Cost of the construction of nuclear power plants is expensive, and interest of money is large. Then, the reduction of construction period is an important problem. The situations of plants approaching to consuming cities in various countries were studied. Idea of group construction is described. (Kato, T.)

  12. Standartization and Terminography of New Construction Terms

    Directory of Open Access Journals (Sweden)

    Zofija Babickienė

    2011-06-01

    Full Text Available The past ten year period showed the occurance of a great number of new construction terms in the Lithua- nian language. Thus it is necessary to collect and systematize construction terms, terminoids, quasi-terms and standardize them from the point of view of the Standard Lithuanian Language taking into account both logic and terminology requirements. This article deals with modern construction terms from the point of view of the Standard Lithuanian Language including newest data bases saving all actual information on them. The reseach showed that The Dictionary of Construction Terms (2003 ought to be included into The Lithuanian language Term Bank (http://terminai.vlkk.lt. It is necessary to be done for the following reasons. Firstly, because of the creation and standartization as well as sistematization process of new construction terms. Secondly, for the development of continuous scientific discusion and successful professional education. It was established that a certain number of construction terms from the point of view of the Standard Lithuanian Language should be included into new Dictionary of Construction Terms as well as into Term Bank of the Lithuanian Republic. The terms analysed in the article are concerning basement types, pile types, construction joints, also details of walls, roofs, chimneys, construction materials and etc. The analysis showed how different morphological variants and undesirable synonymous terms occur. Finally, the analysis helped to identify that the informal terms mix with formal, standard terms and conclude in incorrect term usage.

  13. Professional entrepreneurial identity construction

    DEFF Research Database (Denmark)

    Ramsgaard, Michael Breum

    The present study investigates the construction of a professional identity as an entrepreneur in a sample of people with educational background in nutrition and health. The study examines the connection between professional identity construction and entrepreneurial business emergence using...... ‘entrepreneurial preparedness’ as parameter. This research seeks to address the following questions: What significant components or characteristics do entrepreneurs rely on in the early processes of constructing an entrepreneurial identity....

  14. Imperfect construction of microclusters

    Science.gov (United States)

    Schneider, E.; Zhou, K.; Gilbert, G.; Weinstein, Y. S.

    2014-01-01

    Microclusters are the basic building blocks used to construct cluster states capable of supporting fault-tolerant quantum computation. In this paper, we explore the consequences of errors on microcluster construction using two error models. To quantify the effect of the errors we calculate the fidelity of the constructed microclusters and the fidelity with which two such microclusters can be fused together. Such simulations are vital for gauging the capability of an experimental system to achieve fault tolerance.

  15. VE of construction industry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1987-10-15

    This book gives descriptions of basic of VE of construction industry including doing away with mannerism, necessity of cost reduction, management method of cost reduction, thinking of idea, target of VE, starting VE activity, technical method of VE of construction industry such as thinking of idea with brainstorming, function trade method, new brainstorming, MM method, morphology analysis and lateral thinking, cases of VE of construction industry.

  16. VE of construction industry

    International Nuclear Information System (INIS)

    1987-10-01

    This book gives descriptions of basic of VE of construction industry including doing away with mannerism, necessity of cost reduction, management method of cost reduction, thinking of idea, target of VE, starting VE activity, technical method of VE of construction industry such as thinking of idea with brainstorming, function trade method, new brainstorming, MM method, morphology analysis and lateral thinking, cases of VE of construction industry.

  17. Periodically modulated dark states

    Science.gov (United States)

    Han, Yingying; Zhang, Jun; Zhang, Wenxian

    2018-04-01

    Phenomena of electromagnetically induced transparency (PEIT) may be interpreted by the Autler-Townes Splitting (ATS), where the coupled states are split by the coupling laser field, or by the quantum destructive interference (QDI), where the atomic phases caused by the coupling laser and the probe laser field cancel. We propose modulated experiments to explore the PEIT in an alternative way by periodically modulating the coupling and the probe fields in a Λ-type three-level system initially in a dark state. Our analytical and numerical results rule out the ATS interpretation and show that the QDI interpretation is more appropriate for the modulated experiments. Interestingly, dark state persists in the double-modulation situation where control and probe fields never occur simultaneously, which is significant difference from the traditional dark state condition. The proposed experiments are readily implemented in atomic gases, artificial atoms in superconducting quantum devices, or three-level meta-atoms in meta-materials.

  18. Areca nut is associated with younger age of diagnosis, poor chemoradiotherapy response, and shorter overall survival in esophageal squamous cell carcinoma.

    Directory of Open Access Journals (Sweden)

    Chang-Han Chen

    Full Text Available Areca nut chewing is carcinogenic to humans. However, little is known about the impact of areca nut chewing on esophageal squamous cell carcinoma (ESCC.We retrospectively reviewed 286 ESCC patients who received surgery or preoperative chemoradiotherapy followed by surgery at our institution. Background characteristics including areca nut chewing history were analyzed. The 4-nitroquinoline 1-oxide (4-NQO-induced murine ESCC model was used to test the impact of arecoline, a main constituent of areca nut, on ESCC.Compared to patients without areca nut chewing history, patients with areca nut chewing history had overall a younger age of onset (Mean age: 56.75 versus 52.68 yrs, P<0.001 and significantly worse overall survival than those without areca nut chewing history (P = 0.026. Among patients who received surgery, the overall survival rates were not significantly different between those with or without areca nut chewing history. Among patients who received preoperative chemoradiotherapy followed by surgery, those with areca nut chewing history had a significantly lower pathologic complete response rate (P = 0.002 and lower overall survival rate (P = 0.002 than those without. In the murine ESCC model, the incidence of esophageal invasive squamous cell carcinoma was 40% in mice exposed to concomitant 4-NQO and arecoline treatment for 8 weeks and 6% in mice exposed to 4-NQO only for 8 weeks (P = 0.037.Our results indicate that areca nut chewing history is significantly associated with younger age of onset, poor response to chemoradiotherapy, and shorter overall survival in ESCC patients. Arecoline, a main constituent of areca nut, accelerates esophageal tumorigenesis in the 4-NQO-induced murine ESCC model.

  19. One Gene and Two Proteins: a Leaderless mRNA Supports the Translation of a Shorter Form of the Shigella VirF Regulator

    Directory of Open Access Journals (Sweden)

    Maria Letizia Di Martino

    2016-11-01

    Full Text Available VirF, an AraC-like activator, is required to trigger a regulatory cascade that initiates the invasive program of Shigella spp., the etiological agents of bacillary dysentery in humans. VirF expression is activated upon entry into the host and depends on many environmental signals. Here, we show that the virF mRNA is translated into two proteins, the major form, VirF30 (30 kDa, and the shorter VirF21 (21 kDa, lacking the N-terminal segment. By site-specific mutagenesis and toeprint analysis, we identified the translation start sites of VirF30 and VirF21 and showed that the two different forms of VirF arise from differential translation. Interestingly, in vitro and in vivo translation experiments showed that VirF21 is also translated from a leaderless mRNA (llmRNA whose 5′ end is at position +309/+310, only 1 or 2 nucleotides upstream of the ATG84 start codon of VirF21. The llmRNA is transcribed from a gene-internal promoter, which we identified here. Functional analysis revealed that while VirF30 is responsible for activation of the virulence system, VirF21 negatively autoregulates virF expression itself. Since VirF21 modulates the intracellular VirF levels, this suggests that transcription of the llmRNA might occur when the onset of the virulence program is not required. We speculate that environmental cues, like stress conditions, may promote changes in virF mRNA transcription and preferential translation of llmRNA.

  20. Quasi-periodic luminosity variations in dwarf novae

    International Nuclear Information System (INIS)

    Robinson, E.L.; Nather, R.E.

    1979-01-01

    We have identified quasi-periodic oscillations in the light curves of five dwarf novae--U Gem, SS Cyg, RU Peg, KT Per, and VW Hyi-- and in the light curve of the quasi-periodic X-ray source Sco X-1. The mean periods of the quasi-periodic oscillations range from 32 s in SS Cyg to 147 s in KT Per and 165 s in Sco X-l. Their amplitudes are typically 0.005--0.0l mag. The properties of the quasi-periodic oscillations are represented well by a second-order autoregressive process. Use of this representation shows that the length of time over which the quasi-periodic oscillations maintain coherence is very short, typically 3--5 cycles of the oscillations. Thus the quasi-periodic oscillations can be distinguished from the short-period coherent oscillations in dwarf novae, which are usually interpreted as white dwarf pulsations, because t the periods of the quasi-periodic oscillations are 3--4 times longer and their coherence time is much shorter. The quasi-periodic oscillations occur in dwarf novae only during their eruptions and occur in Sco X-l only when the system is bright. The presence of the oscillations does not depend on the subclass to which a dwarf nova belongs or on the morphology of the individual eruptions. We argue that their short periods, their short coherence times, and their presence in Sco X-l require that the quasi-periodic oscillations be produced by the accretion disk, and not by the stars or by the boundary between the a accretion disk and its central star

  1. Construction Worker Fatigue Prediction Model Based on System Dynamic

    OpenAIRE

    Wahyu Adi Tri Joko; Ayu Ratnawinanda Lila

    2017-01-01

    Construction accident can be caused by internal and external factors such as worker fatigue and unsafe project environment. Tight schedule of construction project forcing construction worker to work overtime in long period. This situation leads to worker fatigue. This paper proposes a model to predict construction worker fatigue based on system dynamic (SD). System dynamic is used to represent correlation among internal and external factors and to simulate level of worker fatigue. To validate...

  2. Advanced construction methods for new nuclear power plants

    International Nuclear Information System (INIS)

    Bilbao y Leon, Sama; Cleveland, John; Moon, Seong-Gyun; Tyobeka, Bismark

    2009-01-01

    The length of the construction and commissioning phases of nuclear power plants have historically been longer than for conventional fossil fuelled plants, often having a record of delays and cost overruns as a result from several factors including legal interventions and revisions of safety regulations. Recent nuclear construction projects however, have shown that long construction periods for nuclear power plants are no longer the norm. While there are several inter-related factors that influence the construction time, the use of advanced construction techniques has contributed significantly to reducing the construction length of recent nuclear projects. (author)

  3. [Childhood periodic syndromes].

    Science.gov (United States)

    Cuvellier, J-C; Lépine, A

    2010-01-01

    This review focuses on the so-called "periodic syndromes of childhood that are precursors to migraine", as included in the Second Edition of the International Classification of Headache Disorders. Three periodic syndromes of childhood are included in the Second Edition of the International Classification of Headache Disorders: abdominal migraine, cyclic vomiting syndrome and benign paroxysmal vertigo, and a fourth, benign paroxysmal torticollis is presented in the Appendix. The key clinical features of this group of disorders are the episodic pattern and intervals of complete health. Episodes of benign paroxysmal torticollis begin between 2 and 8 months of age. Attacks are characterized by an abnormal inclination and/or rotation of the head to one side, due to cervical dystonia. They usually resolve by 5 years. Benign paroxysmal vertigo presents as sudden attacks of vertigo, accompanied by inability to stand without support, and lasting seconds to minutes. Age at onset is between 2 and 4 years, and the symptoms disappear by the age of 5. Cyclic vomiting syndrome is characterized in young infants and children by repeated stereotyped episodes of pernicious vomiting, at times to the point of dehydration, and impacting quality of life. Mean age of onset is 5 years. Abdominal migraine remains a controversial issue and presents in childhood with repeated stereotyped episodes of unexplained abdominal pain, nausea and vomiting occurring in the absence of headache. Mean age of onset is 7 years. Both cyclic vomiting syndrome and abdominal migraine are noted for the absence of pathognomonic clinical features but also for the large number of other conditions to be considered in their differential diagnoses. Diagnostic criteria, such as those of the Second Edition of the International Classification of Headache Disorders and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, have made diagnostic approach and management easier. Their diagnosis

  4. The periodic system of chemical elements: old and new developments

    International Nuclear Information System (INIS)

    Kibler, M.

    1987-09-01

    Some historical facts about the construction of a periodic system of chemical elements are reviewed. The Madelung rule is used to generate an unusual format for the periodic table. Following the work of Byakov, Kulakov, Rumer and Fet, such a format is further refined on the basis of a chain of groups starting with SU(2)xS0(4.2)

  5. Nonparametric Inference for Periodic Sequences

    KAUST Repository

    Sun, Ying; Hart, Jeffrey D.; Genton, Marc G.

    2012-01-01

    the periodogram, a widely used tool for period estimation. The CV method is computationally simple and implicitly penalizes multiples of the smallest period, leading to a "virtually" consistent estimator of integer periods. This estimator is investigated both

  6. Periodic safety analyses; Les essais periodiques

    Energy Technology Data Exchange (ETDEWEB)

    Gouffon, A; Zermizoglou, R

    1990-12-01

    The IAEA Safety Guide 50-SG-S8 devoted to 'Safety Aspects of Foundations of Nuclear Power Plants' indicates that operator of a NPP should establish a program for inspection of safe operation during construction, start-up and service life of the plant for obtaining data needed for estimating the life time of structures and components. At the same time the program should ensure that the safety margins are appropriate. Periodic safety analysis are an important part of the safety inspection program. Periodic safety reports is a method for testing the whole system or a part of the safety system following the precise criteria. Periodic safety analyses are not meant for qualification of the plant components. Separate analyses are devoted to: start-up, qualification of components and materials, and aging. All these analyses are described in this presentation. The last chapter describes the experience obtained for PWR-900 and PWR-1300 units from 1986-1989.

  7. Wall Construction; Carpentry: 901892.

    Science.gov (United States)

    Dade County Public Schools, Miami, FL.

    The curriculum guide outlines a course designed to provide instruction in floor and wall layout, and in the diverse methods and construction of walls. Upon completion of this course the students should have acquired a knowledge of construction plans and structural foundations in addition to a basic knowledge of mathematics. The course consists of…

  8. Safety in construction?

    NARCIS (Netherlands)

    Swuste, P.H.J.J.

    2013-01-01

    The available literature on Construction Safety is not very optimistic about the chances of evidence-based safety in the construction industry exerting a positive influence. Many articles indicate that the structures and processes that are designed to ensure safety in the industry are poor. Safety

  9. INDOT Construction Inspection Priorities

    Science.gov (United States)

    2012-05-01

    In the last decade, the Indiana Department of Transportation (INDOT) has experienced an increase in their construction projects (e.g., INDOTs : construction spending was $789 million in 2006 and increased to $1,081.4 million in 2010); while the le...

  10. Employment and winter construction

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place; Larsen, Jacob Norvig

    2011-01-01

    Reduced seasonal building activity in the construction sector is often assumed to be related to hard winter conditions for building activities and poor working conditions for construction workers, resulting in higher costs and poor quality of building products, particularly in the northern hemisp...... of contracts for workers is more likely to explain differences in seasonal activity than climatic or technological factors....

  11. Governmentalities of Construction

    DEFF Research Database (Denmark)

    Gottlieb, Stefan; Jensen, Jens Stissing

    2016-01-01

    In this paper, we apply Foucault’s concept of governmentality in a dual analysis of the formation and transformation of the construction sector and the construction worker. The governmentality concept is well-suited for such an analysis as it directs attention to the ways in which control is the ...

  12. Nuclear reactor constructions

    International Nuclear Information System (INIS)

    Baddley, A.H.

    1981-01-01

    A method of constructing a radiation shielding plug for use in the roof of the coolant containment vault of liquid metal cooled fast breeder reactors is described. The construction allows relative movement of that part of service cables and pipes which are carried by the fixed roof and that part which is carried by the rotatable plug. (U.K.)

  13. Constructional and Conceptual Composition

    Science.gov (United States)

    Dodge, Ellen Kirsten

    2010-01-01

    Goldberg's (1995) recognition that, in addition to various word-level constructions, sentences also instantiate meaningful argument structure constructions enables a non-polysemy-based analysis of various verb 'alternations' (Levin 1993). In such an analysis, meaning variations associated with the use of the same verb in different argument…

  14. Personal Usability Constructs

    DEFF Research Database (Denmark)

    Hertzum, Morten; Clemmensen, Torkil; Hornbæk, Kasper

    2011-01-01

    Whereas the concept of usability is predominantly defined analytically, people relate to systems through personal usability constructs. Based on 48 repertory-grid interviews, this study investigates how such personal constructs are affected by two factors crucial to the international development...

  15. Industrialization for sustainable construction?

    NARCIS (Netherlands)

    Egmond - de Wilde De Ligny, van E.L.C.; Barrett, P; Amaratunga, D.; Haigh, R; Keraminiyage, K.; Pathirage, C

    2010-01-01

    Sustainable construction (SuCo), which genesis dates in the early 1990’s, advocates the creation and operation of a quality and healthy built environment based on resource efficiency, life cycle economics and ecological principles. (Kibert, 2003). Currently the Construction Industry does not meet

  16. El sector de la construcción en la provincia de León a lo largo del periodo 1990-2013 = The construction industry in the province of León during the period 1990-2013

    Directory of Open Access Journals (Sweden)

    Pedro María Martínez Villar

    2014-12-01

    Despite the intense crisis experienced by the sector since 2007, construction activity remains important for the entire provincial economy. Forasmuch as 17.36% of the total of Leon companies have direct activity with construction and its industry continues to provide figures close to 10% of the provincial VAB in terms of employment and the sector still employs 15,200 workers in the province. In this sense, the fact remains that the crisis not only has driven a significant number of workers out of the sector, but it has also caused a significant deterioration of the contractual quality of the new jobs, and resulting in a significant reduction in wages as major characteristics of work sector market adjustment.

  17. Operations management for construction

    CERN Document Server

    March, Chris

    2009-01-01

    Students studying construction management and related subjects need to have a broad understanding of the major aspects of controlling the building processes. Operations Management for Construction is one of three textbooks (Business Organisation, Operations Management and Finance Control) written to systematically cover the field. Focusing on construction sites and operations which are challenging to run, Chris March explores issues such as the setting up of the site, the deciding of the methodology of construction, and the sequence of work and resourcing. As changing and increasing regulations affect the way sites are managed, he also considers the issues and methods of successful administering, safety, quality and environment. Finally, the contractor's responsibility to the environment, including relationships with third parties, selection of materials, waste management and sustainability is discussed. Chris March has a wealth of practical experience in the construction industry, as well as considerable exp...

  18. VENTILATION NEEDS DURING CONSTRUCTION

    International Nuclear Information System (INIS)

    C.R. Gorrell

    1998-01-01

    The purpose of this analysis is to determine ventilation needs during construction and development of the subsurface repository and develop systems to satisfy those needs. For this analysis, construction is defined as pre-emplacement excavation and development is excavation that takes place simultaneously with emplacement. The three options presented in the ''Overall Development and Emplacement Ventilation Systems'' analysis (Reference 5.5) for development ventilation will be applied to construction ventilation in this analysis as well as adding new and updated ventilation factors to each option for both construction and development. The objective of this analysis is to develop a preferred ventilation system to support License Application Design. The scope of this analysis includes: (1) Description of ventilation conditions; (2) Ventilation factors (fire hazards, dust control, construction logistics, and monitoring and control systems); (3) Local ventilation alternatives; (4) Global ventilation options; and (5) Evaluation of options

  19. Family History of Early Infant Death Correlates with Earlier Age at Diagnosis But Not Shorter Time to Diagnosis for Severe Combined Immunodeficiency

    Directory of Open Access Journals (Sweden)

    Anderson Dik Wai Luk

    2017-07-01

    Full Text Available BackgroundSevere combined immunodeficiency (SCID is fatal unless treated with hematopoietic stem cell transplant. Delay in diagnosis is common without newborn screening. Family history of infant death due to infection or known SCID (FH has been associated with earlier diagnosis.ObjectiveThe aim of this study was to identify the clinical features that affect age at diagnosis (AD and time to the diagnosis of SCID.MethodsFrom 2005 to 2016, 147 SCID patients were referred to the Asian Primary Immunodeficiency Network. Patients with genetic diagnosis, age at presentation (AP, and AD were selected for study.ResultsA total of 88 different SCID gene mutations were identified in 94 patients, including 49 IL2RG mutations, 12 RAG1 mutations, 8 RAG2 mutations, 7 JAK3 mutations, 4 DCLRE1C mutations, 4 IL7R mutations, 2 RFXANK mutations, and 2 ADA mutations. A total of 29 mutations were previously unreported. Eighty-three of the 94 patients fulfilled the selection criteria. Their median AD was 4 months, and the time to diagnosis was 2 months. The commonest SCID was X-linked (n = 57. A total of 29 patients had a positive FH. Candidiasis (n = 27 and bacillus Calmette–Guérin (BCG vaccine infection (n = 19 were the commonest infections. The median age for candidiasis and BCG infection documented were 3 months and 4 months, respectively. The median absolute lymphocyte count (ALC was 1.05 × 109/L with over 88% patients below 3 × 109/L. Positive FH was associated with earlier AP by 1 month (p = 0.002 and diagnosis by 2 months (p = 0.008, but not shorter time to diagnosis (p = 0.494. Candidiasis was associated with later AD by 2 months (p = 0.008 and longer time to diagnosis by 0.55 months (p = 0.003. BCG infections were not associated with age or time to diagnosis.ConclusionFH was useful to aid earlier diagnosis but was overlooked by clinicians and not by parents. Similarly, typical clinical features of

  20. In Vitro Comparison of Holmium Lasers: Evidence for Shorter Fragmentation Time and Decreased Retropulsion Using a Modern Variable-pulse Laser.

    Science.gov (United States)

    Bell, John Roger; Penniston, Kristina L; Nakada, Stephen Y

    2017-09-01

    To compare the performance of variable- and fixed-pulse lasers on stone phantoms in vitro. Seven-millimeter stone phantoms were made to simulate calcium oxalate monohydrate stones using BegoStone plus. The in vitro setting was created with a clear polyvinyl chloride tube. For each trial, a stone phantom was placed at the open end of the tubing. The Cook Rhapsody H-30 variable-pulse laser was tested on both long- and short-pulse settings and was compared to the Dornier H-20 fixed-pulse laser; 5 trials were conducted for each trial arm. Fragmentation was accomplished with the use of a flexible ureteroscope and a 273-micron holmium laser fiber using settings of 1 J × 12 Hz. The treatment time (in minute) for complete fragmentation was recorded as was the total retropulsion distance (in centimeter) during treatment. Laser fibers were standardized for all repetitions. The treatment time was significantly shorter with the H-30 vs the H-20 laser (14.3 ± 2.5 vs 33.1 ± 8.9 minutes, P = .008). There was no difference between the treatment times using the long vs short pulse widths of the H-30 laser (14.4 ± 3.4 vs 14.3 ± 1.7 minutes, P = .93). Retropulsion differed by laser type and pulse width, H-30 long pulse (15.8 ± 5.7 cm), H-30 short pulse (54.8 ± 7.1 cm), and H-20 (33.2 ± 12.5 cm) (P laser fragmented stone phantoms in half the time of the H-20 laser regardless of the pulse width. Retropulsion effects differed between the lasers, with the H-30 causing the least retropulsion. Longer pulse widths result in less stone retropulsion. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Construction in Occupied Spaces

    Directory of Open Access Journals (Sweden)

    Ward Andrew E.

    2017-06-01

    Full Text Available Conducting construction activities in occupied environments presents a great challenge due to the additional logistical requirements and the presence of the building occupants. The aim of this research is to gather and evaluate the means and methods to successfully plan, manage, and execute construction activities in occupied spaces in an effort to provide consolidated industry tools and strategies for maintaining a schedule and minimizing the impact on the occupants. The methodology of the research utilizes an exploratory approach to gather qualitative data. The data was collected through interviews with industry professionals to identify industry best practices. The semi-structured interviews provided a platform for the documents, lessons learned, and the techniques and strategies used for occupied construction by the construction industry. The information obtained in the interview process identified six themes that are critical to achieving and maintaining quality in occupied construction. These themes of the schedule, cost, customer satisfaction, planning, fire/life safety and utilities, and contractor management are reviewed in detail, and the paper discusses how to manage each element. The analysis and extracted management techniques, procedures and strategies can be used by the construction industry for future projects by focusing on the critical aspects of occupied construction and the manner in which to succeed with it.

  2. Construction in Occupied Spaces

    Science.gov (United States)

    Ward, Andrew E.; Azhar, Salman; Khalfan, Malik

    2017-06-01

    Conducting construction activities in occupied environments presents a great challenge due to the additional logistical requirements and the presence of the building occupants. The aim of this research is to gather and evaluate the means and methods to successfully plan, manage, and execute construction activities in occupied spaces in an effort to provide consolidated industry tools and strategies for maintaining a schedule and minimizing the impact on the occupants. The methodology of the research utilizes an exploratory approach to gather qualitative data. The data was collected through interviews with industry professionals to identify industry best practices. The semi-structured interviews provided a platform for the documents, lessons learned, and the techniques and strategies used for occupied construction by the construction industry. The information obtained in the interview process identified six themes that are critical to achieving and maintaining quality in occupied construction. These themes of the schedule, cost, customer satisfaction, planning, fire/life safety and utilities, and contractor management are reviewed in detail, and the paper discusses how to manage each element. The analysis and extracted management techniques, procedures and strategies can be used by the construction industry for future projects by focusing on the critical aspects of occupied construction and the manner in which to succeed with it.

  3. Testing periodically integrated autoregressive models

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); M.J. McAleer (Michael)

    1997-01-01

    textabstractPeriodically integrated time series require a periodic differencing filter to remove the stochastic trend. A non-periodic integrated time series needs the first-difference filter for similar reasons. When the changing seasonal fluctuations for the non-periodic integrated series can be

  4. Magnetospheric Truncation, Tidal Inspiral, and the Creation of Short-period and Ultra-short-period Planets

    International Nuclear Information System (INIS)

    Lee, Eve J.; Chiang, Eugene

    2017-01-01

    Sub-Neptunes around FGKM dwarfs are evenly distributed in log orbital period down to ∼10 days, but dwindle in number at shorter periods. Both the break at ∼10 days and the slope of the occurrence rate down to ∼1 day can be attributed to the truncation of protoplanetary disks by their host star magnetospheres at corotation. We demonstrate this by deriving planet occurrence rate profiles from empirical distributions of pre-main-sequence stellar rotation periods. Observed profiles are better reproduced when planets are distributed randomly in disks—as might be expected if planets formed in situ—rather than piled up near disk edges, as would be the case if they migrated in by disk torques. Planets can be brought from disk edges to ultra-short (<1 day) periods by asynchronous equilibrium tides raised on their stars. Tidal migration can account for how ultra-short-period planets are more widely spaced than their longer-period counterparts. Our picture provides a starting point for understanding why the sub-Neptune population drops at ∼10 days regardless of whether the host star is of type FGK or early M. We predict planet occurrence rates around A stars to also break at short periods, but at ∼1 day instead of ∼10 days because A stars rotate faster than stars with lower masses (this prediction presumes that the planetesimal building blocks of planets can drift inside the dust sublimation radius).

  5. Magnetospheric Truncation, Tidal Inspiral, and the Creation of Short-period and Ultra-short-period Planets

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eve J.; Chiang, Eugene, E-mail: evelee@berkeley.edu [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States)

    2017-06-10

    Sub-Neptunes around FGKM dwarfs are evenly distributed in log orbital period down to ∼10 days, but dwindle in number at shorter periods. Both the break at ∼10 days and the slope of the occurrence rate down to ∼1 day can be attributed to the truncation of protoplanetary disks by their host star magnetospheres at corotation. We demonstrate this by deriving planet occurrence rate profiles from empirical distributions of pre-main-sequence stellar rotation periods. Observed profiles are better reproduced when planets are distributed randomly in disks—as might be expected if planets formed in situ—rather than piled up near disk edges, as would be the case if they migrated in by disk torques. Planets can be brought from disk edges to ultra-short (<1 day) periods by asynchronous equilibrium tides raised on their stars. Tidal migration can account for how ultra-short-period planets are more widely spaced than their longer-period counterparts. Our picture provides a starting point for understanding why the sub-Neptune population drops at ∼10 days regardless of whether the host star is of type FGK or early M. We predict planet occurrence rates around A stars to also break at short periods, but at ∼1 day instead of ∼10 days because A stars rotate faster than stars with lower masses (this prediction presumes that the planetesimal building blocks of planets can drift inside the dust sublimation radius).

  6. Construction and Demolition Waste

    DEFF Research Database (Denmark)

    Christensen, Thomas Højlund; Andersen, L.

    2011-01-01

    Construction and demolition waste (C&D waste) is the waste generated during the building, repair, remodeling or removal of constructions. The constructions can be roads, residential housing and nonresidential buildings. C&D waste has traditionally been considered without any environmental problems...... should be managed accordingly. Another reason is that it has been documented that a large fraction of C&D waste (about 90 %) can be easily recycled and thus can conserve landfill capacity. C&D waste may conveniently be divided into three subcategories: Buildings, roads and excavations. This chapter...

  7. Construction program management

    CERN Document Server

    Delaney, Joseph

    2013-01-01

    Although construction is one of the largest industries in the United States, it lags behind other industries in its implementation of modern management techniques such as those contained in the Standard for Program Management (the Standard) by the Project Management Institute (PMI(R)). Construction Program Management details the successful use of the PMI(R) approach for the construction of capital programs. It demonstrates, through case studies, how implementation of PMI's set of tools and techniques can improve the chances of program success. Exploring tactical and strategic management method

  8. Sustainability Base Construction Update

    Science.gov (United States)

    Mewhinney, Michael

    2012-01-01

    Construction of the new Sustainability Base Collaborative support facility, expected to become the highest performing building in the federal government continues at NASA's Ames Research Center, Moffet Field, Calif. The new building is designed to achieve a platinum rating under the leadership in Energy and Environment Design (LEED) new construction standards for environmentally sustainable construction developed by the U. S. Green Building Council, Washington, D. C. When completed by the end of 2011, the $20.6 million building will feature near zero net energy consumption, use 90 percent less potable water than conventionally build buildings of equivalent size, and will result in reduced building maintenance costs.

  9. EPR project construction cost control

    International Nuclear Information System (INIS)

    Duflo, D.; Pouget-Abadie, X.; Dufour, A.; Kauffmann, G.

    2001-01-01

    The EPR project is now managed by EDF in cooperation with the German Utilities. The main engineering activities for this period are related to the preparation of construction project management, deepening of some safety issues, definition of the project technical reference. The EPR project concerns the so-called reference unit, that is an isolated first-off unit, with unit electrical power of about 1500 MW. The construction costs evaluated are those of the nuclear island, the conventional island, site facilities, installation work and the administrative buildings. The EPR project construction cost evaluation method applies to all the equipment installed and commissioned. It requires the availability of a preliminary project detailed enough to identify the bill of quantities. To these quantities are then assigned updated unit prices that are based either on cost bases for similar and recent facilities or taken from request for quotation for similar equipment or result from gains due to contractual conditions benefiting from simplifications in the functional and technical specifications. The input and output data are managed in a model that respects the breakdown on which the evaluation method is based. The structural organization of this method reflects a functional breakdown on the one hand (nuclear island, conventional island, common site elements) and on the other hand a breakdown according to equipment or activity (civil engineering, mechanics, electricity, instrumentation and control). This paper discusses the principle and the method of construction cost evaluation carried out, the cost data base and input and output parameters as well as results and oncoming cost analysis tasks. (author)

  10. Construction of an access shaft for LEP

    CERN Document Server

    1983-01-01

    The main contract for underground work in the plain was signed end of February 1983. It foresaw a five-month preparation period before the order to start construction work could be issued. The latter was delivered on 1 September. See Annual Report 1983 p. 114

  11. Construction, fabrication, and installation

    International Nuclear Information System (INIS)

    1992-05-01

    This standard specifies the construction, fabrication, and installation requirements that apply to concrete containment structures of a containment system designated as class containment components, parts and appurtenances for nuclear power plants

  12. Construction of anhydrite dams

    Energy Technology Data Exchange (ETDEWEB)

    Bortoluzzi, L; Francois, G

    1977-05-01

    To construct a ventilation dam, the road is closed with a fibreglass sheet onto which 3 or 4 cm of anhydrite paste is sprayed. The equipment necessary is described, and the cost is compared with that of an aggregate dam.

  13. Construction Minerals Operations

    Data.gov (United States)

    Department of Homeland Security — This map layer includes construction minerals operations in the United States. The data represent commodities covered by the Minerals Information Team (MIT) of the...

  14. Caltrans : construction manual

    Science.gov (United States)

    2009-08-01

    Caltrans intends this manual as a resource for all personnel engaged in contract administration. The manual establishes policies and procedures for the construction phase of Caltrans projects. However, this manual is not a contract document. It impos...

  15. Lead in Construction

    National Research Council Canada - National Science Library

    1993-01-01

    Although Occupational Safety and Health Administration (OSHA) regulations for occupational lead exposure have been in effect since 1971 for the construction and general industries, the agency regulations for general industry in 1978...

  16. On Construction Grammar

    Institute of Scientific and Technical Information of China (English)

    XIAO Kunxue

    2005-01-01

    Constructionist approach with its brand-new perspective has begun to demonstrate its dynamic power. This paper attempts to review the basic ideas, achievements and comparison with generative grammar of Construction Grammar and generalize some problems and future research prospects.

  17. Nuclear power plant construction

    International Nuclear Information System (INIS)

    Lima Moreira, Y.M. de.

    1979-01-01

    The legal aspects of nuclear power plant construction in Brazil, derived from governamental political guidelines, are presented. Their evolution, as a consequence of tecnology development is related. (A.L.S.L.) [pt

  18. Skin Problems in Construction

    Science.gov (United States)

    ... you work with… Wet cement or plaster Abrasive cleaners Paints Adhesives Chemical solvents These materials can contain ... health hazards construction workers face on the job. Production of this card was supported by Grant OH009762 ...

  19. Passive solar construction handbook

    Energy Technology Data Exchange (ETDEWEB)

    Levy, E.; Evans, D.; Gardstein, C.

    1981-08-01

    Many of the basic elements of passive solar design are reviewed. The unique design constraints presented in passive homes are introduced and many of the salient issues influencing design decisions are described briefly. Passive solar construction is described for each passive system type: direct gain, thermal storage wall, attached sunspace, thermal storage roof, and convective loop. For each system type, important design and construction issues are discussed and case studies illustrating designed and built examples of the system type are presented. Construction details are given and construction and thermal performance information is given for the materials used in collector components, storage components, and control components. Included are glazing materials, framing systems, caulking and sealants, concrete masonry, concrete, brick, shading, reflectors, and insulators. The Load Collector Ratio method for estimating passive system performance is appended, and other analysis methods are briefly summarized. (LEW)

  20. Photovoltaic roof construction

    Energy Technology Data Exchange (ETDEWEB)

    Hawley, W.W.

    1980-02-26

    In a batten-seam roof construction employing at least one photovoltaic cell module, the electrical conduits employed with the at least one photovoltaic cell module are disposed primarily under the battens of the roof.

  1. Ship construction and welding

    CERN Document Server

    Mandal, Nisith R

    2017-01-01

    This book addresses various aspects of ship construction, from ship types and construction materials, to welding technologies and accuracy control. The contents of the book are logically organized and divided into twenty-one chapters. The book covers structural arrangement with longitudinal and transverse framing systems based on the service load, and explains basic structural elements like hatch side girders, hatch end beams, stringers, etc. along with structural subassemblies like floors, bulkheads, inner bottom, decks and shells. It presents in detail double bottom construction, wing tanks & duct keels, fore & aft end structures, etc., together with necessary illustrations. The midship sections of various ship types are introduced, together with structural continuity and alignment in ship structures. With regard to construction materials, the book discusses steel, aluminum alloys and fiber reinforced composites. Various methods of steel material preparation are discussed, and plate cutting and form...

  2. Construction and material specification

    Science.gov (United States)

    2002-01-01

    These Construction and Material Specifications are written to the Bidder before award of the : Contract and to the Contractor after award of the Contract. The sentences that direct the Contractor to perform Work are written as commands. For example, ...

  3. The ACR: Advanced design features for a short construction schedule

    International Nuclear Information System (INIS)

    Elgohary, M.; Fairclough, N.

    2003-01-01

    Building on the successful CANDU construction at Qinshan, the ACR-700 is designed with constructability considerations as a major requirement during all project phases from the concept design stage to the detail design stage. A project schedule of 48 months has been developed for the nth ACR unit with a 36 months construction period from First Concrete to Fuel Load. This paper describes some of the advanced design features implemented in the reactor building design in order to achieve this short construction period. These features include large volume concrete pours, prefabricated rebar, composite structures, prefabricated permanent formwork and significant modularization and prefabrication

  4. One Gene and Two Proteins: a Leaderless mRNA Supports the Translation of a Shorter Form of the Shigella VirF Regulator.

    Science.gov (United States)

    Di Martino, Maria Letizia; Romilly, Cédric; Wagner, E Gerhart H; Colonna, Bianca; Prosseda, Gianni

    2016-11-08

    VirF, an AraC-like activator, is required to trigger a regulatory cascade that initiates the invasive program of Shigella spp., the etiological agents of bacillary dysentery in humans. VirF expression is activated upon entry into the host and depends on many environmental signals. Here, we show that the virF mRNA is translated into two proteins, the major form, VirF 30 (30 kDa), and the shorter VirF 21 (21 kDa), lacking the N-terminal segment. By site-specific mutagenesis and toeprint analysis, we identified the translation start sites of VirF 30 and VirF 21 and showed that the two different forms of VirF arise from differential translation. Interestingly, in vitro and in vivo translation experiments showed that VirF 21 is also translated from a leaderless mRNA (llmRNA) whose 5' end is at position +309/+310, only 1 or 2 nucleotides upstream of the ATG84 start codon of VirF 21 The llmRNA is transcribed from a gene-internal promoter, which we identified here. Functional analysis revealed that while VirF 30 is responsible for activation of the virulence system, VirF 21 negatively autoregulates virF expression itself. Since VirF 21 modulates the intracellular VirF levels, this suggests that transcription of the llmRNA might occur when the onset of the virulence program is not required. We speculate that environmental cues, like stress conditions, may promote changes in virF mRNA transcription and preferential translation of llmRNA. Shigella spp. are a major cause of dysentery in humans. In bacteria of this genus, the activation of the invasive program involves a multitude of signals that act on all layers of the gene regulatory hierarchy. By controlling the essential genes for host cell invasion, VirF is the key regulator of the switch from the noninvasive to the invasive phenotype. Here, we show that the Shigella virF gene encodes two proteins of different sizes, VirF 30 and VirF 21 , that are functionally distinct. The major form, VirF 30 , activates the genes

  5. Constructive Consumer Choice Processes.

    OpenAIRE

    Bettman, James R; Luce, Mary Frances; Payne, John W

    1998-01-01

    Consumer decision making has been a focal interest in consumer research, and consideration of current marketplace trends ( e.g., technological change, an information explosion) indicates that this topic will continue to be critically important. We argue that consumer choice is inherently constructive. Due to limited processing capacity, consumers often do not have well-defined existing preferences, but construct them using a variety of strategies contingent on task demands. After describing c...

  6. ATLAS construction status

    International Nuclear Information System (INIS)

    Jenni, P.

    2006-01-01

    The ATLAS detector is being constructed at the LHC, in view of a data-taking startup in 2007. This report concentrates on the progress and the technical challenges of the detector construction, and summarizes the status of the work as of August 2004. The project is on track to allow the highly motivated ATLAS Collaboration to enter into a new exploratory domain of high-energy physics in 2007. (author)

  7. International Construction Measurement Standard

    OpenAIRE

    Mitchell, Charles

    2016-01-01

    The International Construction Measurement Standard Coalition (the Coalition) was formed on 17 June 2015 after meeting at the International Monetary Fund in Washington DC, USA. The Coalition, comprising the organisations listed below at the date of publication, aims to bring about consistency in construction cost reporting standards internationally. This is achieved by the creation and adoption of this ICMS, an agreed international standard for the structuring and presentation of cost reports...

  8. Quality during construction

    International Nuclear Information System (INIS)

    Rogers, C.B.

    1977-01-01

    This paper outlines the quality assurance program used by Bechtel Corp. in constructing Nuclear Power Plants. As a tool for scheduling and visualizing situations during construction, power plant scale models are used. The use of models, preplanning, detail scheduling, and early development of procedures and inspection plans, have all contributed to a lower cost integrated quality program. Quality control and quality assurance are built in, thus satisfying the regulatory requirements

  9. AP1000 construction schedule

    International Nuclear Information System (INIS)

    Winters, J.W.

    2001-01-01

    Westinghouse performed this study as part of EPRI interest in advancing the use of computer aided processes to reduce the cost of nuclear power plants. EPRI believed that if one could relate appropriate portions of an advanced light water reactor plant model to activities in its construction sequence, and this relationship could be portrayed visually, then optimization of the construction sequence could be developed as never before. By seeing a 3-D representation of the plant at any point in its construction sequence, more informed decisions can be made on the feasibility or attractiveness of follow on or parallel steps in the sequence. The 3-D representation of construction as a function of time (4-D) could also increase the confidence of potential investors concerning the viability of the schedule and the plant ultimate cost. This study performed by Westinghouse confirmed that it is useful to be able to visualize a plant construction in 3-D as a function of time in order to optimize the sequence of construction activities. (author)

  10. Upper Limit of the Periodic Table and Synthesis of Superheavy Elements

    Directory of Open Access Journals (Sweden)

    Khazan A.

    2007-04-01

    Full Text Available For the first time, using the heaviest possible element, the diagram for known nuclides and stable isotopes is constructed. The direction of search of superheavy elements is indicated. The Periodic Table with an eighth period is tabulated.

  11. Periodical cicadas: A minimal automaton model

    Science.gov (United States)

    de O. Cardozo, Giovano; de A. M. M. Silvestre, Daniel; Colato, Alexandre

    2007-08-01

    The Magicicada spp. life cycles with its prime periods and highly synchronized emergence have defied reasonable scientific explanation since its discovery. During the last decade several models and explanations for this phenomenon appeared in the literature along with a great deal of discussion. Despite this considerable effort, there is no final conclusion about this long standing biological problem. Here, we construct a minimal automaton model without predation/parasitism which reproduces some of these aspects. Our results point towards competition between different strains with limited dispersal threshold as the main factor leading to the emergence of prime numbered life cycles.

  12. Modular construction: 30 years of experience in the naval sector, useful for nuclear power plants

    International Nuclear Information System (INIS)

    Lepelletier, P.; Danguy des Deserts, S.

    2014-01-01

    This article reviews the benefits of modular construction in the sector of submarines that was implemented in the mid eighties in French shipyards. The design of the submarine is cut in different longitudinal parts so that each part can be built and completely equipped independently from the other parts. The different parts are then joined and welded at the end of the process of fabrication to form the submarine. The main advantages of such a construction are shorter construction times, standardized construction and a higher quality standard. DCNS proposes to use modular construction for the design of Flexblue which is an immersed small modular reactor (SMR). More generally, modular construction will add economic competitiveness to SMR reactors that will be necessary to their full development on a worldwide scale

  13. The niche construction perspective: a critical appraisal.

    Science.gov (United States)

    Scott-Phillips, Thomas C; Laland, Kevin N; Shuker, David M; Dickins, Thomas E; West, Stuart A

    2014-05-01

    Niche construction refers to the activities of organisms that bring about changes in their environments, many of which are evolutionarily and ecologically consequential. Advocates of niche construction theory (NCT) believe that standard evolutionary theory fails to recognize the full importance of niche construction, and consequently propose a novel view of evolution, in which niche construction and its legacy over time (ecological inheritance) are described as evolutionary processes, equivalent in importance to natural selection. Here, we subject NCT to critical evaluation, in the form of a collaboration between one prominent advocate of NCT, and a team of skeptics. We discuss whether niche construction is an evolutionary process, whether NCT obscures or clarifies how natural selection leads to organismal adaptation, and whether niche construction and natural selection are of equivalent explanatory importance. We also consider whether the literature that promotes NCT overstates the significance of niche construction, whether it is internally coherent, and whether it accurately portrays standard evolutionary theory. Our disagreements reflect a wider dispute within evolutionary theory over whether the neo-Darwinian synthesis is in need of reformulation, as well as different usages of some key terms (e.g., evolutionary process). © 2013 The Author(s). Evolution published by Wiley Periodicals, Inc. on behalf of The Society for the Study of Evolution.

  14. Integrated construction management technology for power plants

    International Nuclear Information System (INIS)

    Okada, Hisako; Miura, Jun; Nishitani, Yasuhiko

    2003-01-01

    The improvement and rationalization of the plant construction technology has been promoted in order to shorten the construction period, to improve the quality and reliability, and especially to reduce construction costs. With the recent remarkable advances of computer technology, it is necessary to introduce an electronic information technology (IT) into the construction field, and to develop a business process. In such a situation, Hitachi has developed and applied integrated construction support system, which is consistent among design, production and construction. This system has design information and schedule information made electronically as a basic database, and characterizes with project management function based on that information. By introduction of this system, electronic processing of information and reduction of paperwork has enabled high efficiency and standardization of on-site indirect work. Furthermore, by collaboration with the civil company, electrical data exchange has been carried out and developed techniques to improve the interface between mechanical and civil work. High accuracy of construction planning and unification of schedule data have been achieved, and consequently, rework and adjustment at the job site have been greatly reduced. (author)

  15. Constructability and maintainability

    International Nuclear Information System (INIS)

    Hart, R.S.

    1985-01-01

    A set of principles for minimizing the construction schedule was established at the outset of the CANDU 300 programme. Consideration of these principles and other factors led to the development of the unique CANDU 300 station layout. The paper discusses the CANDU 300 station layout and construction methods. In summary, the station layout provides 360 deg. construction access to all buildings, separation of nuclear and non-nuclear systems, precise and minimal physical interfaces between buildings, accommodation of many contractors and construction activities without interference, and maximum flexibility in terms of constructional, financial and supply arrangements. The CANDU 300 further employs modularization, shop fabrication and advanced instrumentation (multiplexers, remote processors, data highways) to minimize construction time. Many of the CANDU 300 features that enhance constructability also contribute to maintainability. These include the 360 deg. access to all principal buildings, the uncluttered and spacious building layouts, the simplification of systems and the high level of modularization. The CANDU 300 has also been designed to facilitate the replacement of all key components, thereby offering an essentially unlimited station life. A prime example is a reduction in the fuel channel inlet end-fitting diameter such that the fuel channels can be shop assembled and easily replaced after the initial 40 years of operation, without an extended unit outage. Maintainability within the reactor building has been given particular attention in the CANDU 300 design; key features of other CANDU reactors (the ability to replace a heat transport system pump motor at power, for example) have been incorporated, while accessibility and maintainability of all systems and components have been enhanced. These and other aspects of maintainability are discussed. (author)

  16. Periodic feedback stabilization for linear periodic evolution equations

    CERN Document Server

    Wang, Gengsheng

    2016-01-01

    This book introduces a number of recent advances regarding periodic feedback stabilization for linear and time periodic evolution equations. First, it presents selected connections between linear quadratic optimal control theory and feedback stabilization theory for linear periodic evolution equations. Secondly, it identifies several criteria for the periodic feedback stabilization from the perspective of geometry, algebra and analyses respectively. Next, it describes several ways to design periodic feedback laws. Lastly, the book introduces readers to key methods for designing the control machines. Given its coverage and scope, it offers a helpful guide for graduate students and researchers in the areas of control theory and applied mathematics.

  17. The redoubtable ecological periodic table

    Science.gov (United States)

    Ecological periodic tables are repositories of reliable information on quantitative, predictably recurring (periodic) habitat–community patterns and their uncertainty, scaling and transferability. Their reliability derives from their grounding in sound ecological principle...

  18. STIMULATION OF CONSTRUCTION OF AFFORDABLE HOUSING BY REFORMATION OF A CONSTRUCTION COMPLEX MANAGEMENT SYSTEM

    Directory of Open Access Journals (Sweden)

    BRONEVYTSKYI S. P.

    2015-10-01

    Full Text Available Purpose. Development of offers on stimulation of construction of affordable housing by reformation of a construction complex management system. Methodology. The revelation of the problems of planning of construction in large cities. The analysis of forming of structure of a build complex management in soviet times and in a transitional period. The revelation of the modern, actual, socio-economic problems of the construction activity management. Proposition on the improvement of methods of construction management in cities of Ukraine. Results. The methods of a construction complex management in countries with a market economy as for building of affordable housing are shown. Originality. In composition of a town-planning documentations, except for the norms of the common use of territories of city (density of population of micro region, the maximum parameters of a construction examining of land areas are proposed to determine: building percent and coefficient of maximum superficial area. Practical value. The principle of management and organization of construction is norms of a build use of territories for building of mass affordable housing for funds of population and investors while providing of the comfort of housing in accordance with state construction norms.

  19. Periodically distributed objects with quasicrystalline diffraction pattern

    Energy Technology Data Exchange (ETDEWEB)

    Wolny, Janusz, E-mail: wolny@fis.agh.edu.pl; Strzalka, Radoslaw [Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, al. Mickiewicza 30, 30-059 Krakow (Poland); Kuczera, Pawel [Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, al. Mickiewicza 30, 30-059 Krakow (Poland); Laboratory of Crystallography, ETH Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich (Switzerland)

    2015-03-30

    It is possible to construct fully periodically distributed objects with a diffraction pattern identical to the one obtained for quasicrystals. These objects are probability distributions of distances obtained in the statistical approach to aperiodic structures distributed periodically. The diffraction patterns have been derived by using a two-mode Fourier transform—a very powerful method not used in classical crystallography. It is shown that if scaling is present in the structure, this two-mode Fourier transform can be reduced to a regular Fourier transform with appropriately rescaled scattering vectors and added phases. Detailed case studies for model sets 1D Fibonacci chain and 2D Penrose tiling are discussed. Finally, it is shown that crystalline, quasicrystalline, and approximant structures can be treated in the same way.

  20. Computer integrated construction at AB building in reprocessing plant

    International Nuclear Information System (INIS)

    Takami, Masahiro; Azuchi, Takehiro; Sekiguchi, Kenji

    1999-01-01

    JNFL (Japan Nuclear Fuel Limited) is now processing with construction of the spent nuclear fuel reprocessing plant at Rokkasho Village in Aomori Prefecture, which is coming near to the busiest period of construction. Now we are trying to complete the civil work of AB Building and KA Building in a very short construction term by applying CIC (Computer Integrated Construction) concept, in spite of its hard construction conditions, such as the massive and complicated building structure, interferences with M and E (Mechanical and Electrical) work, severe winter weather, remote site location, etc. The key technologies of CIC are three-dimensional CAD, information network, and prefabrication and mechanization of site work. (author)

  1. Construction Worker Fatigue Prediction Model Based on System Dynamic

    Directory of Open Access Journals (Sweden)

    Wahyu Adi Tri Joko

    2017-01-01

    Full Text Available Construction accident can be caused by internal and external factors such as worker fatigue and unsafe project environment. Tight schedule of construction project forcing construction worker to work overtime in long period. This situation leads to worker fatigue. This paper proposes a model to predict construction worker fatigue based on system dynamic (SD. System dynamic is used to represent correlation among internal and external factors and to simulate level of worker fatigue. To validate the model, 93 construction workers whom worked in a high rise building construction projects, were used as case study. The result shows that excessive workload, working elevation and age, are the main factors lead to construction worker fatigue. Simulation result also shows that these factors can increase worker fatigue level to 21.2% times compared to normal condition. Beside predicting worker fatigue level this model can also be used as early warning system to prevent construction worker accident

  2. Constructive renormalization theory

    International Nuclear Information System (INIS)

    Rivasseau, Vincent

    2000-01-01

    These notes are the second part of a common course on Renormalization Theory given with Professor P. da Veiga. I emphasize here the rigorous non-perturbative or constructive aspects of the theory. The usual formalism for the renormalization group in field theory or statistical mechanics is reviewed, together with its limits. The constructive formalism is introduced step by step. Taylor forest formulas allow to perform easily the cluster and Mayer expansions which are needed for a single step of the renormalization group in the case of Bosonic theories. The iteration of this single step leads to further difficulties whose solution is briefly sketched. The second part of the course is devoted to Fermionic models. These models are easier to treat on the constructive level so they are very well suited to beginners in constructive theory. It is shown how the Taylor forest formulas allow to reorganize perturbation theory nicely in order to construct the Gross-Neveu 2 model without any need for cluster or Mayer expansions. Finally applications of this technique to condensed matter and renormalization group around Fermi surface are briefly reviewed. (author)

  3. ITER towards the construction

    International Nuclear Information System (INIS)

    Shimomura, Y.

    2005-01-01

    The ITER Project has been significantly developed in the last few years in preparation for its construction. The ITER Participant's Negotiators have developed the Joint Implementation Agreement (JIA), ready for finalisation following selection of the construction site and nomination of the project's Director General. The ITER International Team and Participant Teams have continued technical and organisational preparations. Construction will be able to start immediately after the international ITER organisation is established, following signature of the JIA. The Project is strongly supported by the governments of the Participants as well as by the scientific community. The real negotiations, including siting and the final details of cost sharing, started in December 2003. The EU, with Cadarache, and Japan, with Rokkasho, have both promised large contributions to the project to strongly support their construction site proposals. Their wish to host ITER construction is too strong to allow convergence to a single site considering the ITER device in isolation. A broader collaboration among the Parties is therefore being contemplated, covering complementary activities to help accelerate fusion development towards a viable power source, and allow the Participants to reach a conclusion on ITER siting. This report reviews these preparations, and the status of negotiations

  4. PIK reactor construction status

    International Nuclear Information System (INIS)

    Konoplev, K.A.; Smolsky, S.L.

    2001-01-01

    The 100MW reactor PIK for fundamental researches has a thermal neutron flux of more than 10 15 n/cm 2 sec. This presentation outlines the construction state as of 2001, its prospects and completion tactics in the conditions of unstable finance. Construction of the reactor started in 1976. In 1986 construction of the building was completed and significant part of the installation work fulfilled. Construction of cooling systems was finished, the control panel assembled, and adjustment of the pump and gate valve control circuits started. After Chernobyl catastrophe, the USSR nuclear reactor safety requirements were revised. The PIK design did not meet these requirements and underwent considerable revision. The reconstruction design resulted in double the initial cost. Creation of the containment was the bulkiest part of the reconstruction. It brought about the need to disassemble the roofing of the building, dismantle all the equipment of the two upper floors, and lay up the equipment of the lower floors. As of 2001, construction in accordance with the revised design is at the stage of assemblage of the most important units, i.e. reactor itself, cooling system, heavy water system, and a number of auxiliary systems, such as depleted fuel storage, emergency cooling system etc. (orig.)

  5. A novel methodology to estimate the evolution of construction waste in construction sites.

    Science.gov (United States)

    Katz, Amnon; Baum, Hadassa

    2011-02-01

    This paper focuses on the accumulation of construction waste generated throughout the erection of new residential buildings. A special methodology was developed in order to provide a model that will predict the flow of construction waste. The amount of waste and its constituents, produced on 10 relatively large construction sites (7000-32,000 m(2) of built area) was monitored periodically for a limited time. A model that predicts the accumulation of construction waste was developed based on these field observations. According to the model, waste accumulates in an exponential manner, i.e. smaller amounts are generated during the early stages of construction and increasing amounts are generated towards the end of the project. The total amount of waste from these sites was estimated at 0.2m(3) per 1m(2) floor area. A good correlation was found between the model predictions and actual data from the field survey. Copyright © 2010 Elsevier Ltd. All rights reserved.

  6. Management for Construction Materials and Control of Construction Waste in Construction Industry: A Review

    OpenAIRE

    A. A. Gulghane; Prof P. V. Khandve

    2015-01-01

    In recent treads a wide range of building materials is available for the construction of civil engineering structures. The total cost of materials may be up to 60% or more of the total cost incurred in construction project dependent upon the type of project. Effective construction materials management is a key to success for a construction project. Construction waste is another serious problem in construction industry. A large and various types of construction waste with different...

  7. First-line intra-arterial versus intravenous chemotherapy in unilateral sporadic group D retinoblastoma: evidence of better visual outcomes, ocular survival and shorter time to success with intra-arterial delivery from retrospective review of 20 years of treatment.

    Science.gov (United States)

    Munier, Francis L; Mosimann, Pascal; Puccinelli, Francesco; Gaillard, Marie-Claire; Stathopoulos, Christina; Houghton, Susan; Bergin, Ciara; Beck-Popovic, Maja

    2017-08-01

    The introduction of intra-arterial chemotherapy (IAC) as salvage treatment has improved the prognosis for eye conservation in group D retinoblastoma. The aim of this study was to compare the outcomes of consecutive patients with advanced unilateral disease treated with either first-line intravenous chemotherapy (IVC) or first-line IAC. This is a retrospective mono-centric comparative review of consecutive patients. Sporadic unilateral retinoblastoma group D cases treated conservatively at Jules-Gonin Eye Hospital and CHUV between 1997 and 2014. From January 1997 to August 2008, IVC, combined with focal treatments, was the primary treatment approach. From September 2008 to October 2014, IAC replaced IVC as first-line therapy. 48 patients met the inclusion criteria, receiving only either IAC or IVC as primary treatment modality. Outcomes of 23 patients treated by IVC were compared with those of 25 treated by IAC; mean follow-up was 105.3 months (range 29.2-218.6) and 41.7 months (range 19.6-89.5), respectively. Treatment duration was significantly shorter in the IAC group (pchemotherapy treatment. Despite this, the results reported here imply that eyes treated with first-line IAC will have shorter treatment period, better ocular survival and visual acuity than first-line IVC. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  8. Validation of the Davidson Trauma Scale in its original and a new shorter version in people exposed to the F-27 earthquake in Chile

    Directory of Open Access Journals (Sweden)

    Marcelo C. Leiva-Bianchi

    2013-08-01

    Full Text Available Background: On February 27, 2010 (F-27, an earthquake and tsunami occurred having a significant impact on the mental health of the Chilean population, leading to an increase in cases of post-traumatic stress disorder (PTSD. Objectives: Within this context, validated for the first time in Chile was the Davidson Trauma Scale (DTS using three samples (each one consisting of 200 participants, two of them random from the Chilean population. Results: Reliability analyses (i.e., α=0.933, concurrent validity (63% of the items are significantly correlated with the criteria variable “degree of damage to home” and construct validity (i.e., CMIN = 3.754, RMSEA = 0.118, NFI = 0.808, CFI = 0.850 and PNFI = 0.689 indicate validity between regular and good for DTS. However, a new short version of the scale (DTS-SF created using the items with heavier factor weights, presented better fits (CMIN = 2.170, RMSEA = 0.077, NFI = 0.935, CFI = 0.963, PNFI = 0.697. Discussion: Finally, the usefulness of DTS and DTS-SF is discussed, the latter being briefer, valid and having better psychometric characteristics.

  9. Labor construction trends

    International Nuclear Information System (INIS)

    McCall, H.W.

    1976-01-01

    The increasing costs and schedule delays being experienced in construction projects have led companies to look for alternatives to their present methods of expansion. One of the facets being evaluated is the construction labor posture. As a result, more companies are employing open shop contractors. Certain benefits can be realized by open shop construction. Productivity, in terms of the time required and overall costs, is definitely improved at no sacrifice in quality. Before an owner decides to build a project open shop, however, he must be fully aware of the pro's and con's of both types of labor posture. He must know to select a capable open shop contractor and he must realize his obligations for a successful open shop program

  10. Reliability and construction control

    Directory of Open Access Journals (Sweden)

    Sherif S. AbdelSalam

    2016-06-01

    Full Text Available The goal of this study was to determine the most reliable and efficient combination of design and construction methods required for vibro piles. For a wide range of static and dynamic formulas, the reliability-based resistance factors were calculated using EGYPT database, which houses load test results for 318 piles. The analysis was extended to introduce a construction control factor that determines the variation between the pile nominal capacities calculated using static versus dynamic formulae. From the major outcomes, the lowest coefficient of variation is associated with Davisson’s criterion, and the resistance factors calculated for the AASHTO method are relatively high compared with other methods. Additionally, the CPT-Nottingham and Schmertmann method provided the most economic design. Recommendations related to a pile construction control factor were also presented, and it was found that utilizing the factor can significantly reduce variations between calculated and actual capacities.

  11. Perception of User Criteria in the Context of Sustainability of Modern Methods of Construction Based on Wood

    Directory of Open Access Journals (Sweden)

    Jozef Švajlenka

    2018-01-01

    Full Text Available Recent developments in the construction industry have brought more efficient and sustainable technologies, technological procedures, and materials. An example of this are modern methods of construction, which offer larger production volumes with a higher quality and shorter procurement time. The goal of those methods is to improve construction sustainability through quality improvement, customer satisfaction, shortened construction time, and reduced environmental impact. The main goal of this research is to demonstrate, by means of theoretical assumptions, surveys, and analyses, the sustainability of modern methods of construction based on wood. The work focuses on identifying the user criteria for construction sustainability. Selected user criteria of construction sustainability are applied in a socio-economic survey whose purpose is to determine how users perceive the efficiency of selected construction systems. We evaluate certain user parameters in the context of sustainability by relying on the users of buildings (family houses which have already been built and compare the results with declared design parameters.

  12. Analysis of nuclear power plant construction costs

    International Nuclear Information System (INIS)

    1986-01-01

    The objective of this report is to present the results of a statistical analysis of nuclear power plant construction costs and lead-times (where lead-time is defined as the duration of the construction period), using a sample of units that entered construction during the 1966-1977 period. For more than a decade, analysts have been attempting to understand the reasons for the divergence between predicted and actual construction costs and lead-times. More importantly, it is rapidly being recognized that the future of the nuclear power industry rests precariously on an improvement in the cost and lead-time situation. Thus, it is important to study the historical information on completed plants, not only to understand what has occurred to also to improve the ability to evaluate the economics of future plants. This requires an examination of the factors that have affected both the realized costs and lead-times and the expectations about these factors that have been formed during the construction process. 5 figs., 22 tabs

  13. Analysis of nuclear power plant construction costs

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    The objective of this report is to present the results of a statistical analysis of nuclear power plant construction costs and lead-times (where lead-time is defined as the duration of the construction period), using a sample of units that entered construction during the 1966-1977 period. For more than a decade, analysts have been attempting to understand the reasons for the divergence between predicted and actual construction costs and lead-times. More importantly, it is rapidly being recognized that the future of the nuclear power industry rests precariously on an improvement in the cost and lead-time situation. Thus, it is important to study the historical information on completed plants, not only to understand what has occurred to also to improve the ability to evaluate the economics of future plants. This requires an examination of the factors that have affected both the realized costs and lead-times and the expectations about these factors that have been formed during the construction process. 5 figs., 22 tabs.

  14. Projected costs of generating electricity from power stations for commissioning in the period 1995-2000

    International Nuclear Information System (INIS)

    1989-01-01

    The study reviews the projected electricity generation costs for the base load power generation options expected to be available in the medium term, using an agreed common economic methodology. Cost projections were obtained for nuclear and fossil fuelled plants that could in principle be commissioned in the mid-1990s, or shortly thereafter, although not all countries plan to commission plants at that time. The major changes in expectations compared with earlier studies, apart from those associated with changed perceptions of fossil fuel prices, include significantly lower nuclear investment costs for the United States, associated with an improved design and the expectation of achieving shorter construction periods than projected in the 1985 study, and generally lower nuclear fuel costs. Some countries project higher operation and maintenance costs for either coal-fired or nuclear plant or both. In the case of coal-fired plants these may be associated with the extra costs of operating desulphurisation equipment. The most marked change in nuclear operating and maintenance costs has taken place in the United States, where these costs are now expected to be twice as large as the projected nuclear fuel costs. There remain major differences in investment cost expectations between countries. The reasons for these differences have been examined in previous studies. They arise from differences in factor costs, regulatory approach, design and siting, and exchange rates which do not adequately reflect the differences in the capital investment costs between countries. In brief, most OECD countries continue to expect nuclear power to have a lower levelised generating cost than coal-fired generation when using their own technical and economic assumptions

  15. Periodic waves in nonlinear metamaterials

    International Nuclear Information System (INIS)

    Liu, Wen-Jun; Xiao, Jing-Hua; Yan, Jie-Yun; Tian, Bo

    2012-01-01

    Periodic waves are presented in this Letter. With symbolic computation, equations for monochromatic waves are studied, and analytic periodic waves are obtained. Factors affecting properties of periodic waves are analyzed. Nonlinear metamaterials, with the continuous distribution of the dielectric permittivity obtained, are different from the ones with the discrete distribution. -- Highlights: ► Equations for the monochromatic waves in transverse magnetic polarization have been studied. ► Analytic periodic waves for the equations have been obtained. ► Periodic waves are theoretically presented and studied in the nonlinear metamaterials.

  16. INFANTILISM: THEORETICAL CONSTRUCT AND OPERATIONALIZATION

    Directory of Open Access Journals (Sweden)

    Yelena V. Sabelnikova

    2016-01-01

    Full Text Available The aim of the presented research is to define and operationalize theoretically the concept of infantilism and its construct. The content of theoretical construct «infantilism» is analyzed. Methods. The methods of theoretical research involve analysis and synthesis. The age and content criteria are analysed in the context of childhood and adulthood. The traits which can be interpreted as adult infantile traits are described. Results. The characteristics of adult infantilism in modern world taking into account the increasing of information flows and socio-economic changes are defined. The definition of the concept «infantilism» including its main features is given. Infantilism is defined as the personal organization including features and models of the previous age period not adequate for the real age stage with emphasis on immaturity of the emotional and volitional sphere. Scientific novelty. The main psychological characteristics of adulthood are described as the reflection, requirement to work and professional activity, existence of professional self-determination, possession of labor skills, need for selfrealization, maturity of the emotional and volitional sphere. As objective adulthood characteristics are considered the following: transition to economic and territorial independence of a parental family, and also development of new social roles, such as a worker, spouse, and parent. Two options of a possible operationalization of concept are allocated: objective (existence / absence in real human life of objective criteria of adulthood and subjective (the self-report on subjective feeling of existence / lack of psychological characteristics of adulthood. Practical significance consists in a construct operationalization of «infantilism» which at the moment has so many interpretations. That operationalization is necessary for the further analysis and carrying out various researches. 

  17. Nonparametric Inference for Periodic Sequences

    KAUST Repository

    Sun, Ying

    2012-02-01

    This article proposes a nonparametric method for estimating the period and values of a periodic sequence when the data are evenly spaced in time. The period is estimated by a "leave-out-one-cycle" version of cross-validation (CV) and complements the periodogram, a widely used tool for period estimation. The CV method is computationally simple and implicitly penalizes multiples of the smallest period, leading to a "virtually" consistent estimator of integer periods. This estimator is investigated both theoretically and by simulation.We also propose a nonparametric test of the null hypothesis that the data have constantmean against the alternative that the sequence of means is periodic. Finally, our methodology is demonstrated on three well-known time series: the sunspots and lynx trapping data, and the El Niño series of sea surface temperatures. © 2012 American Statistical Association and the American Society for Quality.

  18. Construction Management Meets Today's Realities.

    Science.gov (United States)

    Day, C. William

    1979-01-01

    Construction management--the control of cost and time from concept through construction--grew out of a need to meet the realities of today's economy. A checklist of services a construction manager provides is presented. (Author/MLF)

  19. Construction Manager or General Contractor?

    Science.gov (United States)

    McKinley, John

    1991-01-01

    Unlike the general contractor approach, the construction management firm acts on behalf of the school district in school construction. Examines the development and nature of construction management, and cites its advantages and disadvantages. (MLF)

  20. PWR plant construction in Japan

    International Nuclear Information System (INIS)

    Tamura, Toshifumi

    2002-01-01

    The construction methods based on the experiences on the Nuclear Island, which is a critical path in the total construction schedule, have been studied and reconsidered in order to construct by more reliable and economical method. So various improved construction method are being applied and the duration of construction is being reduced continuously. So various improved construction method are being applied and the duration of construction is being reduced continuously. In this paper, the history of construction of twenty-three (23) PWR Plant, the actual construction methods and schedule of Ohi-3/4, to which the many improved methods were applied during their construction, are introduced mainly with the improved points for previously constructed plants. And also the situation of construction method for the next PWR Plant is simply explained

  1. Rationalizing of construction engineering of nuclear power plants with pressurized water reactors

    International Nuclear Information System (INIS)

    Schmidt, S.

    1977-01-01

    Construction of large power plants requires further reduction of construction efforts and the construction period. A new constructional and technological solution has been developed with the steel-cell composite structure applied in the Greifswald nuclear power plant 'Bruno Leuschner' for the first time. Principles of design, fabrication, transport, and mounting are described. The benefits of the method are indicated. (author)

  2. Positive periodic solutions of delayed periodic Lotka-Volterra systems

    International Nuclear Information System (INIS)

    Lin Wei; Chen Tianping

    2005-01-01

    In this Letter, for a general class of delayed periodic Lotka-Volterra systems, we prove some new results on the existence of positive periodic solutions by Schauder's fixed point theorem. The global asymptotical stability of positive periodic solutions is discussed further, and conditions for exponential convergence are given. The conditions we obtained are weaker than the previously known ones and can be easily reduced to several special cases

  3. Periodic permanent magnet focusing system with high peak field

    International Nuclear Information System (INIS)

    Zhang Hong; Liu Weiwei; Bai Shuxin; Chen Ke

    2008-01-01

    In this study, hybrid periodic permanent magnet (PPM) system is studied, which has high axial magnetic field and low magnetic leakage. By simulation computation, some laws of magnetic field distribution vs. structure dimensions were obtained. A hybrid PPM is designed and constructed whose peak field reaches 0.6 T. The factors inducing discrepancies between computational results and practical measurements are analyzed. The magnetic field distribution is very sensitive to the variations of constructional parameters. Construction accuracy greatly influences the magnetic field distribution. Research results obtained here are potentially valuable for future work

  4. Construction contract risk and reasonable evasions

    International Nuclear Information System (INIS)

    Wu Yunpeng

    2012-01-01

    Construction project has the characteristics such as large-scale investment, long-period implementation, excessive uncertainties,a single piece of production, etc. These characteristics determine the complexity of a construction project contract. To guarantee the time limit and quality of a project, finding ways to reduce and evade the contract risks as well as avoid unnecessary disputes are urgent requirements for each project manager. According to the practical situation, project contract risks are analyzed and illustrated in detail, and the concrete solutions for evading those risks are put forward. (authors)

  5. Gentilly 2: design, construction and commissioning

    International Nuclear Information System (INIS)

    Amyot, Paul; Michel, Benoit.

    1982-06-01

    Construction of the Gentilly 2 power station is essentially complete, and commissioning is proceeding. The main activities during the 1981-82 period have been the completion of the construction and overall testing of the major systems. One cause of delay in the project in 1981 was the discovery of damage to the tubesheet of a steam generator. An internal manhole cover support in the steam generator head had become loose and had caused damage to the tube-to-tubesheet welds. Repairs to the welds were completed in Feb. 1982 after an extensive development program to qualify the welding procedure. Overall project life will be slightly more than 9 years

  6. Design and construction of nuclear power plants

    CERN Document Server

    Schnell, Jürgen; Meiswinkel, Rüdiger; Bergmeister, Konrad; Fingerloos, Frank; Wörner, Johann-Dietrich

    2013-01-01

    Despite all the efforts being put into expanding renewable energy sources, large-scale power stations will be essential as part of a reliable energy supply strategy for a longer period. Given that they are low on CO2 emissions, many countries are moving into or expanding nuclear energy to cover their baseload supply.Building structures required for nuclear installations whose protective function means they are classified as safety-related, have to meet particular construction requirements more stringent than those involved in conventional construction. This book gives a comprehensive overv

  7. Photolysis of Periodate and Periodic Acid in Aqueous Solution

    DEFF Research Database (Denmark)

    Sehested, Knud; Kläning, U. K.

    1978-01-01

    The photochemistry of periodate and periodic acid in aqueous solution was studied (i) by quantum yield measurements at low light intensity (ii) by flash photolysis, and (iii) by photolysis of glassy samples at 77 K. The photochemical studies were supplemented with pulse radiolysis studies...... of aqueous periodate solutions and with kinetic studies using stopped-flow technique. In strongly alkaline solution the photodecomposition of periodate proceeds via formation of O– and IVI. At pH solution O3 P is formed in a small...

  8. The shorter the better? A follow-up analysis of 10-session psychiatric treatment including the motive-oriented therapeutic relationship for borderline personality disorder.

    Science.gov (United States)

    Kramer, Ueli; Stulz, Niklaus; Berthoud, Laurent; Caspar, Franz; Marquet, Pierre; Kolly, Stéphane; De Roten, Yves; Despland, Jean-Nicolas

    2017-05-01

    There is little research on short-term treatments for borderline personality disorder (BPD). While the core changes may occur only in long-term treatments, short-term treatments may enable the study of early generic processes of engagement in therapy and thus inform about effective treatment components. It was shown that a 10-session version of a psychiatric treatment was effective in reducing borderline symptoms at the end of this treatment [Kramer, U., Kolly, S., Berthoud, L., Keller, S., Preisig, M., Caspar, F., … Despland, J.-N. (2014). Effects of motive-oriented therapeutic relationship in a ten-session general psychiatric treatment for borderline personality disorder: A randomized controlled trial. Psychotherapy and Psychosomatics, 83, 176-186.]. Also, it was demonstrated in a randomized design that adding the motive-oriented therapeutic relationship (MOTR), following an individualized case formulation based on Plan Analysis, further increased general outcome after session 10 and had a positive effect on the early changes in self-esteem and alliance. The present study focuses on the follow-up period after this initial treatment, examining treatment density and outcomes after 6 months and service utilization after 12 months. Outcome was measured using the OQ-45. Results on a sub-sample of N = 40 patients with available OQ-45 data at follow-up (n = 21 for MOTR-treatment, n = 19 for comparison treatment) showed maintenance of gains over the follow-up period, which did not differ between both conditions. It appeared for this sample that MOTR treatments, while using the same number of sessions, lasted more weeks (i.e., lower treatment density, defined as the number of sessions per week), when compared to the treatments without MOTR. Density marginally predicted symptom reduction at follow-up. Patients in MOTR treatments had a greater likelihood of entering structured psychotherapy after the initial sessions than patients in the comparison

  9. Constructive Preference Elicitation

    Directory of Open Access Journals (Sweden)

    Paolo Dragone

    2018-01-01

    Full Text Available When faced with large or complex decision problems, human decision makers (DM can make costly mistakes, due to inherent limitations of their memory, attention, and knowledge. Preference elicitation tools assist the decision maker in overcoming these limitations. They do so by interactively learning the DM’s preferences through appropriately chosen queries and suggesting high-quality outcomes based on the preference estimates. Most state-of-the-art techniques, however, fail in constructive settings, where the goal is to synthesize a custom or entirely novel configuration rather than choosing the best option among a given set of candidates. Many wide-spread problems are constructive in nature: customizing composite goods such as cars and computers, bundling products, recommending touristic travel plans, designing apartments, buildings, or urban layouts, etc. In these settings, the full set of outcomes is humongous and can not be explicitly enumerated, and the solution must be synthesized via constrained optimization. In this article, we describe recent approaches especially designed for constructive problems, outlining the underlying ideas and their differences as well as their limitations. In presenting them, we especially focus on novel issues that the constructive setting brings forth, such as how to deal with sparsity of the DM’s preferences, how to properly frame the interaction, and how to achieve efficient synthesis of custom instances.

  10. Construction Management: Planning Ahead.

    Science.gov (United States)

    Arsht, Steven

    2003-01-01

    Explains that preconstruction planning is essential when undertaking the challenges of a school building renovation or expansion, focusing on developing a detailed estimate, creating an effective construction strategy, conducting reviews and value-engineering workshops, and realizing savings through effective risk analysis and contingency…

  11. ACCELERATING CONSTRUCTION INDUSTRY DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Mohan M. Kumaraswamy

    2006-06-01

    Full Text Available The needs for construction industry development are initially viewed from the broader perspectives of imperatives for infrastructure development and national development. All these are clearly more critical in developing countries. A non-exhaustive set of potential drivers and common barriers to construction industry development is identified from previous research. These suggest the usefulness of consolidating a cluster of recent proposals and exercises aiming at (a construction organization development in terms of an over-arching management support system model, as well as improved information and knowledge management; and (b project team development in the context of relationally integrated teams and supply chains, joint risk management and ‘technology and knowledge exchange’ in joint ventures, as well as longer term public private partnerships. These apparently disparate research thrusts are threaded together into a pattern that may inspire, if not feed, specific research and development (R & D agendas for construction industry development in different countries according to their own priorities, constraints and stages of infrastructure and national development.

  12. Constructions of Peripherality

    DEFF Research Database (Denmark)

    Carter, Helen Frances Lindsay

    2013-01-01

    In this paper I focus on the concept of peripheralisation. In particular, I consider how peripheries can be discursively constructed in the debates surrounding planning cases, and how this might serve to legitimate particular interests. This is related to the case of a proposed golf resort...

  13. Nanotechnologies for sustainable construction

    DEFF Research Database (Denmark)

    Geiker, Mette Rica; Andersen, Maj Munch

    2009-01-01

    This chapter aims to highlight key aspects and recent trends in the development and application of nanotechnology to facilitate sustainable construction, use and demolition of buildings and infrastructure structures, ‘nanoconstruction’. Nanotechnology is not a technology but a very diverse...

  14. Provability Calculus of Constructions

    DEFF Research Database (Denmark)

    Nyblad, Kasten

    This thesis presents a type system, Provability Calculus of Constructions (PCoC) that can be used for the formalization of logic. In a theorem prover based on the system, the user can extend the prover with new inference rules in a logically consistent manner. This is done by representing PCo...

  15. KARATE WITH CONSTRUCTIVE LEARNING

    Directory of Open Access Journals (Sweden)

    Srikrishna Karanam

    2012-02-01

    Full Text Available Any conventional learning process involves the traditional hierarchy of garnering of information and then recall gathered information. Constructive learning is an important research area having wide impact on teaching methods in education, learning theories, and plays a major role in many education reform movements. It is observed that constructive learning advocates the interconnection between emotions and learning. Human teachers identify the emotions of students with varying degrees of accuracy and can improve the learning rate of the students by motivating them. In learning with computers, computers also should be given the capability to recognize emotions so as to optimize the learning process. Image Processing is a very popular tool used in the process of establishing the theory of Constructive Learning. In this paper we use the Optical Flow computation in image sequences to analyze the accuracy of the moves of a karate player. We have used the Lucas-Kanade method for computing the optical flow in image sequences. A database consisting of optical flow images by a group of persons learning karate is formed and the learning rates are analyzed in order to main constructive learning. The contours of flow images are compared with the standard images and the error graphs are plotted. Analysis of the emotion of the amateur karate player is made by observing the error plots.

  16. Mortality table construction

    Science.gov (United States)

    Sutawanir

    2015-12-01

    Mortality tables play important role in actuarial studies such as life annuities, premium determination, premium reserve, valuation pension plan, pension funding. Some known mortality tables are CSO mortality table, Indonesian Mortality Table, Bowers mortality table, Japan Mortality table. For actuary applications some tables are constructed with different environment such as single decrement, double decrement, and multiple decrement. There exist two approaches in mortality table construction : mathematics approach and statistical approach. Distribution model and estimation theory are the statistical concepts that are used in mortality table construction. This article aims to discuss the statistical approach in mortality table construction. The distributional assumptions are uniform death distribution (UDD) and constant force (exponential). Moment estimation and maximum likelihood are used to estimate the mortality parameter. Moment estimation methods are easier to manipulate compared to maximum likelihood estimation (mle). However, the complete mortality data are not used in moment estimation method. Maximum likelihood exploited all available information in mortality estimation. Some mle equations are complicated and solved using numerical methods. The article focus on single decrement estimation using moment and maximum likelihood estimation. Some extension to double decrement will introduced. Simple dataset will be used to illustrated the mortality estimation, and mortality table.

  17. Constructions in Wonderland

    DEFF Research Database (Denmark)

    Jensen, Kim Ebensgaard; Shibuya, Yoshikata

    -gram analysis to some different texts, including Lewis Carroll's 1865 novel Alice's Adventures in Wonderland (AW), Mark Twain's 1884/5 novel The Adventures of Huckleberry Finn (HF), and some US presidential speeches, to identify frequently (co)occurring words that may be indicative of underlying constructions...

  18. Constructing Regional advantage

    DEFF Research Database (Denmark)

    Asheim, Bjørn T.; Boschma, Ron; Cooke, Phil

    2011-01-01

    This paper presents a regional innovation policy model based on the idea of constructing regional advantage. This policy model brings together concepts like related variety, knowledge bases and policy platforms. Related variety attaches importance to knowledge spillovers across complementary...... economic development within and between regions in action lines appropriate to incorporate the basic principles behind related variety and differentiated knowledge bases....

  19. Predictable grammatical constructions

    DEFF Research Database (Denmark)

    Lucas, Sandra

    2015-01-01

    My aim in this paper is to provide evidence from diachronic linguistics for the view that some predictable units are entrenched in grammar and consequently in human cognition, in a way that makes them functionally and structurally equal to nonpredictable grammatical units, suggesting that these p......My aim in this paper is to provide evidence from diachronic linguistics for the view that some predictable units are entrenched in grammar and consequently in human cognition, in a way that makes them functionally and structurally equal to nonpredictable grammatical units, suggesting...... that these predictable units should be considered grammatical constructions on a par with the nonpredictable constructions. Frequency has usually been seen as the only possible argument speaking in favor of viewing some formally and semantically fully predictable units as grammatical constructions. However, this paper...... semantically and formally predictable. Despite this difference, [méllo INF], like the other future periphrases, seems to be highly entrenched in the cognition (and grammar) of Early Medieval Greek language users, and consequently a grammatical construction. The syntactic evidence speaking in favor of [méllo...

  20. AA under construction

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    The AA at an early stage of construction, in the newly built AA-Hall. Cable-trays already outline the shape of the accumulator ring. To the right are huge cable-drums for the pulse-forming-network (PFN) of the injection kicker. Seeing this picture, can one imagine that only 8 months later beams were circulating in the completed accumulator ring ?

  1. Housing and construction

    Science.gov (United States)

    Delton Alderman

    2014-01-01

    OECD economies, in aggregate, have been sluggish; unemployment remains high in several countries, and minimal gross domestic product gains are forecast for the Euro area through 2016. Recession, sovereign debt problems and lethargic economies continue to constrain Europe’s housing construction market; no improvement is expected before 2015 or...

  2. Patterns of Knowledge Construction

    Science.gov (United States)

    Chang, Bo

    2018-01-01

    The purpose of this study was to identify knowledge construction patterns in a local learning community. Observation, documents, and semistructured interviews were employed to collect data. Twenty learners were interviewed. Data were analyzed inductively using the constant comparative method. Five major patterns--radiation, circulation,…

  3. Neuroeconomics: Constructing identity

    NARCIS (Netherlands)

    Davis, J.B.

    2010-01-01

    The paper asks whether neuroeconomics will make instrumental use of neuroscience to adjudicate existing disputes in economics or be more seriously transformed by neuroscience in ways that might transform economics. The paper pursues the question by asking how neuroscience constructs an understanding

  4. Construction of monophase nets

    International Nuclear Information System (INIS)

    Suarez A, Jose Antonio

    1996-01-01

    The paper refers to the use of monophase loads in commercial residential urbanizations and in small industries, for this reason it is considered unnecessary the construction of three-phase nets. The author makes a historical recount of these nets in Bogota, his capacities, uses and energy savings

  5. Anyonic FRT construction

    International Nuclear Information System (INIS)

    Majid, S.; Rodriguez-Plaza, M.J.

    1994-01-01

    The Faddeev-Reshetikhin-Takhtajan method to construct matrix bialgebras from non-singular solutions of the quantum Yang-Baxter equation is extended to the anyonic or Z n -graded case. The resulting anyonic quantum matrices are braided groups in which the braiding is given by a phase factor. (orig.)

  6. Federal Environmental Requirements for Construction

    Data.gov (United States)

    Department of Veterans Affairs — This guide provides information on federal environmental requirements for construction projects. It is written primarily for owners of construction projects and for...

  7. Information systems for material flow management in construction processes

    Science.gov (United States)

    Mesároš, P.; Mandičák, T.

    2015-01-01

    The article describes the options for the management of material flows in the construction process. Management and resource planning is one of the key factors influencing the effectiveness of construction project. It is very difficult to set these flows correctly. The current period offers several options and tools to do this. Information systems and their modules can be used just for the management of materials in the construction process.

  8. ALGORITHMIC CONSTRUCTION SCHEDULES IN CONDITIONS OF TIMING CONSTRAINTS

    Directory of Open Access Journals (Sweden)

    Alexey S. Dobrynin

    2014-01-01

    Full Text Available Tasks of time-schedule construction (JSSP in various fields of human activities have an important theoretical and practical significance. The main feature of these tasks is a timing requirement, describing allowed planning time periods and periods of downtime. This article describes implementation variations of the work scheduling algorithm under timing requirements for the tasks of industrial time-schedules construction, and service activities.

  9. Indigenous lunar construction materials

    Science.gov (United States)

    Rogers, Wayne P.; Sture, Stein

    1991-01-01

    The utilization of local resources for the construction and operation of a lunar base can significantly reduce the cost of transporting materials and supplies from Earth. The feasibility of processing lunar regolith to form construction materials and structural components is investigated. A preliminary review of potential processing methods such as sintering, hot-pressing, liquification, and cast basalt techniques, was completed. The processing method proposed is a variation on the cast basalt technique. It involves liquification of the regolith at 1200-1300 C, casting the liquid into a form, and controlled cooling. While the process temperature is higher than that for sintering or hot-pressing (1000-1100 C), this method is expected to yield a true engineering material with low variability in properties, high strength, and the potential to form large structural components. A scenario for this processing method was integrated with a design for a representative lunar base structure and potential construction techniques. The lunar shelter design is for a modular, segmented, pressurized, hemispherical dome which could serve as habitation and laboratory space. Based on this design, estimates of requirements for power, processing equipment, and construction equipment were made. This proposed combination of material processing method, structural design, and support requirements will help to establish the feasibility of lunar base construction using indigenous materials. Future work will refine the steps of the processing method. Specific areas where more information is needed are: furnace characteristics in vacuum; heat transfer during liquification; viscosity, pouring and forming behavior of molten regolith; design of high temperature forms; heat transfer during cooling; recrystallization of basalt; and refinement of estimates of elastic moduli, compressive and tensile strength, thermal expansion coefficient, thermal conductivity, and heat capacity. The preliminary

  10. Innovative quality management practices in the Dutch construction industry

    NARCIS (Netherlands)

    Bossink, B.A.G.

    2002-01-01

    Quality management practices do support the management of strategically important innoυation processes. This conclusion is based on empirical research in the Dutch construction industry. A large-scale innovative construction project is intensively studied during a three-year period. The quality

  11. How Do Earth-Sized, Short-Period Planets Form?

    Science.gov (United States)

    Kohler, Susanna

    2017-08-01

    Matching theory to observation often requires creative detective work. In a new study, scientists have used a clever test to reveal clues about the birth of speedy, Earth-sized planets.Former Hot Jupiters?Artists impression of a hot Jupiter with an evaporating atmosphere. [NASA/Ames/JPL-Caltech]Among the many different types of exoplanets weve observed, one unusual category is that of ultra-short-period planets. These roughly Earth-sized planets speed around their host stars at incredible rates, with periods of less than a day.How do planets in this odd category form? One popular theory is that they were previously hot Jupiters, especially massive gas giants orbiting very close to their host stars. The close orbit caused the planets atmospheres to be stripped away, leaving behind only their dense cores.In a new study, a team of astronomers led by Joshua Winn (Princeton University) has found a clever way to test this theory.Planetary radius vs. orbital period for the authors three statistical samples (colored markers) and the broader sample of stars in the California Kepler Survey. [Winn et al. 2017]Testing MetallicitiesStars hosting hot Jupiters have an interesting quirk: they typically have metallicities that are significantly higher than an average planet-hosting star. It is speculated that this is because planets are born from the same materials as their host stars, and hot Jupiters require the presence of more metals to be able to form.Regardless of the cause of this trend, if ultra-short-period planets are in fact the solid cores of former hot Jupiters, then the two categories of planets should have hosts with the same metallicity distributions. The ultra-short-period-planet hosts should therefore also be weighted to higher metallicities than average planet-hosting stars.To test this, the authors make spectroscopic measurements and gather data for a sample of stellar hosts split into three categories:64 ultra-short-period planets (orbital period shorter than a

  12. Periodic instantons and scattering amplitudes

    International Nuclear Information System (INIS)

    Khlebnikov, S.Yu.; Rubakov, V.A.; Tinyakov, P.G.

    1991-04-01

    We discuss the role of periodic euclidean solutions with two turning points and zero winding number (periodic instantons) in instanton induced processes below the sphaleron energy E sph . We find that the periodic instantons describe certain multiparticle scattering events leading to the transitions between topologically distinct vacua. Both the semiclassical amplitudes and inital and final states of these transitions are determined by the periodic instantons. Furthermore, the corresponding probabilities are maximal among all states of given energy. We show that at E ≤ E sph , the periodic instantons can be approximated by infinite chains of ordinary instantons and anti-instantons, and they naturally emerge as deformations of the zero energy instanton. In the framework of 2d abelian Higgs model and 4d electroweak theory we show, however, that there is not obvious relation between periodic instantons and two-particle scattering amplitudes. (orig.)

  13. Microprocessor controlled digital period meter

    International Nuclear Information System (INIS)

    Keefe, D.J.; McDowell, W.P.; Rusch, G.K.

    1980-01-01

    A microprocessor controlled digital period meter has been developed and tested operationally on a reactor at Argonne National Laboratory. The principle of operation is the mathematical relationship between asymptotic periods and pulse counting circuitry. This relationship is used to calculate and display the reactor periods over a range of /plus or minus/1 second to /plus or minus/999 seconds. The time interval required to update each measurement automatically varies from 8 seconds at the lowest counting rates to 2 seconds at higher counting rates. The paper will describe hardware and software design details and show the advantages of this type of Period Meter over the conventional circuits. 1 ref

  14. Construction materials and Radon

    International Nuclear Information System (INIS)

    Paschuk, Sergei A.; Correa, Janine Nicolosi; Loriane, Fior; Schelin, Hugo R.; Pottker, Fabiana; Paula Melo, Vicente de

    2008-01-01

    Full text: Current studies have been performed with the aim to find the correlation of radon concentration in the air and used construction materials. At the first stage of the measurements different samples of materials used in civil construction were studied as a source of radon in the air and at the second step it was studied the radon infiltration insulation using different samples of finishing materials. For 222 Rn concentration measurements related to different construction materials as well as for the studies of radon emanation and its reduction, the sealed cell chambers, of approximately 60 x 60cm 2 , have been built using the ceramic and concrete blocks. This construction has been performed within protected and isolated laboratory environment to maintain the air humidity and temperature stable. These long term measurements have been performed using polycarbonate alpha track passive detectors. The exposure time was set about 15 days considering previous calibration performed at the Institute of Radiation Protection and Dosimetry (IRD/CNEN), where the efficiency of 70% was obtained for the density of alpha particle tracks about 13.8 cm -2 per exposure day and per kBq/m 3 of radon activity concentration. The chemical development of alpha tracks has been achieved by electrochemical etching. The track identification and counting have been done using a code based on the MATLAB Image Processing Toolbox. The cell chambers have been built following four principle steps: 1) Assembling the walls using the blocks and mortar; 2) Plaster installation; 3) Wall surface finishing using the lime; 4) Wall surface insulation by paint. Making the comparison between three layers installed at the masonry walls from concrete and ceramic blocks, it could be concluded that only wall painting with acrylic varnish attended the expectation and reduced the radon emanation flow by the factor of 2.5 approximately. Studied construction materials have been submitted the instant

  15. Doubly periodic solutions of the modified Kawahara equation

    International Nuclear Information System (INIS)

    Zhang Dan

    2005-01-01

    Some doubly periodic (Jacobi elliptic function) solutions of the modified Kawahara equation are presented in closed form. Our approach is to introduce a new auxiliary ordinary differential equation and use its Jacobi elliptic function solutions to construct doubly periodic solutions of the modified Kawahara equation. When the module m → 1, these solutions degenerate to the exact solitary wave solutions of the equation. Then we reveal the relation of some exact solutions for the modified Kawahara equation obtained by other authors

  16. Recognition method of construction conflict based on driver's eye movement.

    Science.gov (United States)

    Xu, Yi; Li, Shiwu; Gao, Song; Tan, Derong; Guo, Dong; Wang, Yuqiong

    2018-04-01

    Drivers eye movement data in simulated construction conflicts at different speeds were collected and analyzed to find the relationship between the drivers' eye movement and the construction conflict. On the basis of the relationship between the drivers' eye movement and the construction conflict, the peak point of wavelet processed pupil diameter, the first point on the left side of the peak point and the first blink point after the peak point are selected as key points for locating construction conflict periods. On the basis of the key points and the GSA, a construction conflict recognition method so called the CCFRM is proposed. And the construction conflict recognition speed and location accuracy of the CCFRM are verified. The good performance of the CCFRM verified the feasibility of proposed key points in construction conflict recognition. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Tools for Social Construction

    DEFF Research Database (Denmark)

    Brynskov, Martin

    for social construction, i.e. supporting staging, performing, and sharing of playful activities involving people and artifacts.             The method used is a triangulation of the problem domain—pervasive media systems for children—from three perspectives: theory, design, and empirical work......: the potential of pervasive media systems to support the children’s social construction.  ......In this dissertation, I propose a new type of playful media for children. Based on field work, prototypes, and theoretical development, I define, build, and explore a distinct cross-section of existing and new digital media, tools, and communication devices in order to assess the characteristics...

  18. Construction quality assurance report

    International Nuclear Information System (INIS)

    Roscha, V.

    1994-01-01

    This report provides a summary of the construction quality assurance (CQA) observation and test results, including: The results of the geosynthetic and soil materials conformance testing. The observation and testing results associates with the installation of the soil liners. The observation and testing results associated with the installation of the HDPE geomembrane liner systems. The observation and testing results associated with the installation of the leachate collection and removal systems. The observation and testing results associated with the installation of the working surfaces. The observation and testing results associated with in-plant manufacturing process. Summary of submittal reviews by Golder Construction Services, Inc. The submittal and certification of the piping material specifications. The observation and verification associated of the Acceptance Test Procedure results of the operational equipment functions. Summary of the ECNs which are incorporated into the project

  19. Constructing criticality by classification

    DEFF Research Database (Denmark)

    Machacek, Erika

    2017-01-01

    " in the bureaucratic practice of classification: Experts construct material criticality in assessments as they allot information on the materials to the parameters of the assessment framework. In so doing, they ascribe a new set of connotations to the materials, namely supply risk, and their importance to clean energy......, legitimizing a criticality discourse.Specifically, the paper introduces a typology delineating the inferences made by the experts from their produced recommendations in the classification of rare earth element criticality. The paper argues that the classification is a specific process of constructing risk....... It proposes that the expert bureaucratic practice of classification legitimizes (i) the valorisation that was made in the drafting of the assessment framework for the classification, and (ii) political operationalization when enacted that might have (non-)distributive implications for the allocation of public...

  20. Interspecific studies of circadian genes period and timeless in Drosophila.

    Science.gov (United States)

    Noreen, Shumaila; Pegoraro, Mirko; Nouroz, Faisal; Tauber, Eran; Kyriacou, Charalambos P

    2018-03-30

    The level of rescue of clock function in genetically arrhythmic Drosophila melanogaster hosts using interspecific clock gene transformation was used to study the putative intermolecular coevolution between interacting clock proteins. Among them PER and TIM are the two important negative regulators of the circadian clock feedback loop. We transformed either the D. pseudoobscura per or tim transgenes into the corresponding arrhythmic D. melanogaster mutant (per01 or tim01) and observed >50% rhythmicity but the period of activity rhythm was either longer (D. pseudoobscura-per) or shorter than 24 h (D. pseudoobscura-tim) compared to controls. By introducing both transgenes simultaneously into double mutants, we observed that the period of the activity rhythm was rescued by the pair of hemizygous transgenes (~24 h). These flies also showed a more optimal level of temperature compensation for the period. Under LD 12:12 these flies have a D. pseudoobscura like activity profile with the absence of morning anticipation as well as a very prominent earlier evening peak of activity rhythm. These observation are consistent with the view that TIM and PER form a heterospecific coevolved module at least for the circadian period of activity rhythms. However the strength of rhythmicity was reduced by having both transgenes present, so while evidence for a coevolution between PER and TIM is observed for some characters it is not for others. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  1. Lunar concrete for construction

    Science.gov (United States)

    Cullingford, Hatice S.; Keller, M. Dean

    1988-01-01

    Feasibility of using concrete for lunar-base construction has been discussed recently without relevant data for the effects of vacuum on concrete. Experimental studies performed earlier at Los Alamos have shown that concrete is stable in vacuum with no deterioration of its quality as measured by the compressive strength. Various considerations of using concrete successfully on the moon are provided in this paper along with specific conclusions from the existing data base.

  2. Nanotechnologies for sustainable construction

    DEFF Research Database (Denmark)

    Geiker, Mette Rica; Andersen, Maj Munch

    2009-01-01

    This chapter aims to highlight key aspects and recent trends in the development and application of nanotechnology to facilitate sustainable construction, use and demolition of buildings and infrastructure structures, ‘nanoconstruction’. Nanotechnology is not a technology but a very diverse...... technological field which covers many aspects. The chapter therefore seeks to provide a framework for addressing relevant issues of green nanoconstruction and to bring an overview and illustrative examples of current early developments....

  3. Industry Studies 2002: Construction

    Science.gov (United States)

    2002-01-01

    Jacksonville, FL Rotary Club of San Juan, San Juan, PR Tren Urbano Subway Project, San Juan, PR U.S. Army South, San Juan, PR U.S. Coast Guard Housing Project...Bechtel Corporation (IBM Plant Construction Site), Shanghai American Chamber of Commerce, Shanghai Urban Planning Exhibit, Shanghai 3 INTRODUCTION The...of states have or are working on a statewide or agency-wide privatization plan , including California, Maryland, Massachusetts, Michigan and

  4. LEAR construction completed

    CERN Multimedia

    CERN PhotoLab

    1982-01-01

    In July 1982, LEAR construction was completed, the individual systems had been dry-tested. On 16 July, the first 50 MeV (309 MeV/c) protons from Linac 1 were injected and circulated. On 11 October, the first antiprotons from the AA, decelerated in the PS to 609 MeV/c, were injected. Also in 1982, acceleration, deceleration and stochastic cooling were successfully tested. See 9007366 for a more detailed description. See also 8201061, 8204131, 8309026.

  5. Improving construction performance

    International Nuclear Information System (INIS)

    1990-03-01

    Design for Constructability's overall purpose was to identify and address changes in the nuclear industry to restore nuclear energy as an attractive option for new generating capacity. As the centerpiece of project control, a comprehensive, stable schedule should organize the project logically to accomplish the project's objectives. A good schedule will: integrate the project team; serve as a communications tool to all members of the project team; and provide a means to monitor and measure project performance

  6. NRC Construction Experience

    International Nuclear Information System (INIS)

    Rasmussen, Richard

    2013-01-01

    This presentation deals with the domestic and international construction experience sources. From the domestic (USA) point of view, the sources are event notifications, non-compliance reports, inspection reports, etc. Internationally, the presentation highlights the following sources: IRS and ConEx reports, Nuclear Events Web Based System (NEWS), bilateral agreements, MDEP, etc. It also mentions and describes briefly reported on concrete, rebar, fabrication and digital issues

  7. New plant construction cost and schedule

    International Nuclear Information System (INIS)

    Akins, M. J.

    2009-01-01

    The presentation covers the following topics: cost structure; capital costs; variation of capital costs; trends in power plant construction; studies of costs completion; periods and risks. Nuclear plant costs have recently risen so rapidly that vendors are not willing to publicly commit to cost estimates: ∼ $2000/Kw overnight costs in 2006 in the US market > $4000/Kw and in 2008 in the US market > $6000/Kw in 2008 in emerging markets. There is vendors pricing uncertainty. Current contract models may not apply. Current construction projects have problems: Olkiluoto-3 is reported to be 50% over budget and two years behind schedule, increasing perceptions that nuclear costs will continue to increase rapidly; Price of materials is a big volatile unknown, which may decrease Labor could become more available due to limited number of new projects; Lack of debt/credit to finance new project may decrease demand of new construction

  8. Toward a constructive physics

    Energy Technology Data Exchange (ETDEWEB)

    Noyes, H.P.; Gefwert, C.; Manthey, M.J.

    1983-06-01

    We argue that the discretization of physics which has occurred thanks to the advent of quantum mechanics has replaced the continuum standards of time, length and mass which brought physics to maturity by counting. The (arbitrary in the sense of conventional dimensional analysis) standards have been replaced by three dimensional constants: the limiting velocity c, the unit of action h, and either a reference mass (eg m/sub p/) or a coupling constant (eg G related to the mass scale by hc/(2..pi..Gm/sub p//sup 2/) approx. = 1.7 x 10/sup 38/). Once these physical and experimental reference standards are accepted, the conventional approach is to connect physics to mathematics by means of dimensionless ratios. But these standards now rest on counting rather than ratios, and allow us to think of a fourth dimensionless mathematical concept, which is counting integers. According to constructive mathematics, counting has to be understood before engaging in the practice of mathematics in order to avoid redundancy. In its strict form constructive mathematics allows no completed infinities, and must provide finite algorithms for the computation of any acceptable concept. This finite requirement in constructive mathematics is in keeping with the practice of physics when that practice is restricted to hypotheses which are testable in a finite time. In this paper we attempt to outline a program for physics which will meet these rigid criteria while preserving, in so far as possible, the successes that conventional physics has already achieved.

  9. Toward a constructive physics

    International Nuclear Information System (INIS)

    Noyes, H.P.; Gefwert, C.; Manthey, M.J.

    1983-06-01

    We argue that the discretization of physics which has occurred thanks to the advent of quantum mechanics has replaced the continuum standards of time, length and mass which brought physics to maturity by counting. The (arbitrary in the sense of conventional dimensional analysis) standards have been replaced by three dimensional constants: the limiting velocity c, the unit of action h, and either a reference mass (eg m/sub p/) or a coupling constant (eg G related to the mass scale by hc/(2πGm/sub p/ 2 ) approx. = 1.7 x 10 38 ). Once these physical and experimental reference standards are accepted, the conventional approach is to connect physics to mathematics by means of dimensionless ratios. But these standards now rest on counting rather than ratios, and allow us to think of a fourth dimensionless mathematical concept, which is counting integers. According to constructive mathematics, counting has to be understood before engaging in the practice of mathematics in order to avoid redundancy. In its strict form constructive mathematics allows no completed infinities, and must provide finite algorithms for the computation of any acceptable concept. This finite requirement in constructive mathematics is in keeping with the practice of physics when that practice is restricted to hypotheses which are testable in a finite time. In this paper we attempt to outline a program for physics which will meet these rigid criteria while preserving, in so far as possible, the successes that conventional physics has already achieved

  10. Cooperation in Construction:

    DEFF Research Database (Denmark)

    Vogelius, Peter; Storgaard, Kresten

    2016-01-01

    The study presents a building project executed by a major Danish construction company, where cooperation and its staging were essential for achieving high productivity and competitiveness. The form of this cooperation is the main theme for the article. The contractor actively changed the communic......The study presents a building project executed by a major Danish construction company, where cooperation and its staging were essential for achieving high productivity and competitiveness. The form of this cooperation is the main theme for the article. The contractor actively changed...... the companies in the case can be understood as possessing a social capital which is enforced and united by initiatives of the main contractor. The social capital was built up and maintained through the actual constitution of cooperation already in the initial phase of bidding before the building process....... The management logic of the main contractor is interpreted as based on a sociology-inspired understanding focusing on norms and social values rather than on contractual (law) and functional (engineering) logic, which had hitherto been prevalent in Danish construction management....

  11. Toward construction of ITER

    International Nuclear Information System (INIS)

    Shimomura, Yasuo

    2005-01-01

    The ITER Project has been significantly developed in the past years in preparation for its construction. The ITER Negotiators have developed a draft Joint Implementation Agreement (JIA), ready for completion following the nomination of the Project's Director General (DG). The ITER International Team and Participant Teams have continued technical and organizational preparations. The actual construction will be able to start immediately after the international ITER organization will be established, following signature of the JIA. The Project is now strongly supported by all the participants as well as by the scientific community with the final high-level negotiations, focused on siting and the concluding details of cost sharing, started in December 2003. The EU, with Cadarache, and Japan, with Rokkasho, have both promised large contributions to the project to strongly support their construction site proposals. The extent to which they both wish to host the ITER facility is such that large contributions to a broader collaboration among the Parties are also proposed by them. This covers complementary activities to help accelerate fusion development towards a viable power source, as well as may allow the Participants to reach a conclusion on ITER siting. (author)

  12. INFINITY construction contract signed

    Science.gov (United States)

    2010-01-01

    Key state and community leaders celebrated April 6 with the signing of a construction contract for the state-of-the-art INFINITY Science Center planned near John C. Stennis Space Center in south Mississippi. Gulfport Mayor George Schloegel (l to r), chair of non-profit INFINITY Science Center Inc., was joined for the signing ceremony at the Hancock Bank in Gulfport by Virginia Wagner, sister of late Hancock Bank President Leo Seal Jr.; and Roy Anderson III, president and CEO of Roy Anderson Corp. Seal was the first chair of INFINITY Science Center Inc., which has led in development of the project. Roy Anderson Corp. plans to begin construction on the 72,000-square-foot, $28 million science and education center in May. The Mississippi Department of Transportation (MDOT) also is set to begin construction of a $2 million access road to the new center. The April 6 ceremony was attended by numerous officials, including former Stennis Space Center Directors Jerry Hlass and Roy Estess; Mississippi Senate President Pro Tempore Billy Hewes, R-Gulfport; Mississippi Rep. Diane Peranich, D-Pass Christian; and MDOT Southern District Commissioner Wayne Brown.

  13. Forward Period Analysis Method of the Periodic Hamiltonian System.

    Directory of Open Access Journals (Sweden)

    Pengfei Wang

    Full Text Available Using the forward period analysis (FPA, we obtain the period of a Morse oscillator and mathematical pendulum system, with the accuracy of 100 significant digits. From these results, the long-term [0, 1060] (time unit solutions, ranging from the Planck time to the age of the universe, are computed reliably and quickly with a parallel multiple-precision Taylor series (PMT scheme. The application of FPA to periodic systems can greatly reduce the computation time of long-term reliable simulations. This scheme provides an efficient way to generate reference solutions, against which long-term simulations using other schemes can be tested.

  14. Detecting periodicities with Gaussian processes

    Directory of Open Access Journals (Sweden)

    Nicolas Durrande

    2016-04-01

    Full Text Available We consider the problem of detecting and quantifying the periodic component of a function given noise-corrupted observations of a limited number of input/output tuples. Our approach is based on Gaussian process regression, which provides a flexible non-parametric framework for modelling periodic data. We introduce a novel decomposition of the covariance function as the sum of periodic and aperiodic kernels. This decomposition allows for the creation of sub-models which capture the periodic nature of the signal and its complement. To quantify the periodicity of the signal, we derive a periodicity ratio which reflects the uncertainty in the fitted sub-models. Although the method can be applied to many kernels, we give a special emphasis to the Matérn family, from the expression of the reproducing kernel Hilbert space inner product to the implementation of the associated periodic kernels in a Gaussian process toolkit. The proposed method is illustrated by considering the detection of periodically expressed genes in the arabidopsis genome.

  15. Scheduling periodic tasks with slack

    NARCIS (Netherlands)

    Korst, J.H.M.; Aarts, E.H.L.; Lenstra, J.K.

    1997-01-01

    We consider the problem of nonpreemptively scheduling periodic tasks on a minimum number of identical processors, assuming that some slack is allowed in the time between successive executions of a periodic task. We prove that the problem is NP-hard in the strong sense. Necessary and sufficient

  16. Quantum periods of Calabi–Yau fourfolds

    Energy Technology Data Exchange (ETDEWEB)

    Gerhardus, Andreas, E-mail: gerhardus@th.physik.uni-bonn.de; Jockers, Hans, E-mail: jockers@uni-bonn.de

    2016-12-15

    In this work we study the quantum periods together with their Picard–Fuchs differential equations of Calabi–Yau fourfolds. In contrast to Calabi–Yau threefolds, we argue that the large volume points of Calabi–Yau fourfolds generically are regular singular points of the Picard–Fuchs operators of non-maximally unipotent monodromy. We demonstrate this property in explicit examples of Calabi–Yau fourfolds with a single Kähler modulus. For these examples we construct integral quantum periods and study their global properties in the quantum Kähler moduli space with the help of numerical analytic continuation techniques. Furthermore, we determine their genus zero Gromov–Witten invariants, their Klemm–Pandharipande meeting invariants, and their genus one BPS invariants. In our computations we emphasize the features attributed to the non-maximally unipotent monodromy property. For instance, it implies the existence of integral quantum periods that at large volume are purely worldsheet instanton generated. To verify our results, we also present intersection theory techniques to enumerate lines with a marked point on complete intersection Calabi–Yau fourfolds in Grassmannian varieties.

  17. Rationalization of Comet Halley's periods

    Science.gov (United States)

    Belton, Michael J. S.

    1990-01-01

    The sense of long axis orientation of Comet Halley during the Vega 1 encounter must be reversed from that deduced by Sagdeev et al. (1986) in order to harmonize the comet nucleus' Vega/Giotto-observed orientations with periodicities extracted from time-series brightness data. It is also demonstrated that Vega/Giotto observations can be satisfied by either a 2.2- or 3.7-day long-axis free precession period. A novel Fourier algorithm is used to reanalyze five independent data sets; strong evidence is adduced for periods harmonically related to a 7.4-day period. The preferred candidate models for Halley's nuclear rotation are characterized by a long-axis precession period of 3.7 days.

  18. Orbital periods of recurrent novae

    International Nuclear Information System (INIS)

    Schaefer, B.E.

    1990-01-01

    The class of recurrent novae (RN) with thermonuclear runaways contains only three systems (T Pyx, U Sco, and V394 CrA), for which no orbital periods are known. This paper presents a series of photometric observations where the orbital periods for all three systems are discovered. T Pyx is found to have sinusoidal modulation with an amplitude of 0.08 mag and a period of 2.3783 h (with a possible alias of 2.6403 h). U Sco is found to be an eclipsing system with an eclipse amplitude of roughly 1.5 mag and an orbital period of 1.2344 days. V394 CrA is found to have sinusoidal modulation with an amplitude of 0.5 mag and a period of 0.7577 days. Thus two out of three RN with thermonuclear runaways (or five out of six for all RN) have evolved companions. 16 refs

  19. Impact of modules on the ACR construction schedule

    International Nuclear Information System (INIS)

    Choy, Ed; Elgohary, Medhat; Fairclough, Neville; Yu, Stephen; Murayama, Kouichi; Miura, Jun; Kawahata, Junichi

    2003-01-01

    The ACR (Advanced CANDU Reactor), developed by Atomic Energy of Canada Ltd. (AECL), is designed with constructability considerations as a major requirement during all project phases from the concept design stage to the detail design stage. For ACR-700, a project schedule of 48 months has been developed for the nth replicated unit with a 36 month construction period duration from First Concrete to Fuel Load. AECL, recognizing the immense benefit of collective experience, is partnering with Hitachi Ltd in the development of the ACR power plant design. AECL has gained valuable experience in implementing new construction methods at the Qinshan (Phase III) twin unit CANDU 6 plant in China, and Hitachi likewise has enjoyed success in modular construction of ABWRs in Japan. Utilizing these experiences, AECL is developing the ACR nuclear steam plant (NSP) and Hitachi is developing the Turbine Building. An overall construction strategy, which builds on the success of these construction methods from the nuclear power plant developments in China and Japan, has been developed for the ACR. The overall construction strategy comprises the 'Open Top' construction technique using a Very Heavy Lift crane, parallel construction activities, with extensive modularization and prefabrication. Modules and prefabrications are major features of the ACR design, resulting in an excess of 80% of Reactor Building internal work being completed as modules or as very streamlined traditional construction. This paper reviews the ACR construction strategy and provides examples of modules and how they impact on the ACR construction schedule. In conclusion, the ACR-700 is designed using the latest, proven construction methods to achieve a 36 month construction period for the nth replicated unit. (author)

  20. Chaos to periodicity and periodicity to chaos by periodic perturbations in the Belousov-Zhabotinsky reaction

    International Nuclear Information System (INIS)

    Li Qianshu; Zhu Rui

    2004-01-01

    A three-variable model of the Belousov-Zhabotinsky reaction system subject to external sinusoidal perturbations is investigated by means of frequency spectrum analysis. In the period-1 window of the model, the transitions from periodicity to chaos are observed; in the chaotic window, the transitions from chaos to periodicity are found. The former might be understood by the circle map of two coupled oscillators, and the latter is partly explained by the resonance between the main frequency of the chaos and the frequency of the external periodic perturbations

  1. Radioactive materials in construction projects

    International Nuclear Information System (INIS)

    Herrmann, Ralf; Ohlendorf, Frank; Kaltz, Andrea Christine

    2014-01-01

    Till 1990 residues often of the former uranium mining were partly used as building material for road construction, terrain compensation and house construction in Saxony. These recommendations for action are addressed to applicants, planners and building constructors in the engineering and construction sector. It provides information for planning, preliminary investigations, applications, construction supervision related to radiation protection measures and documentation of construction projects where radioactive materials are expected.

  2. Applying lean thinking in construction

    Directory of Open Access Journals (Sweden)

    Remon Fayek Aziz

    2013-12-01

    Full Text Available The productivity of the construction industry worldwide has been declining over the past 40 years. One approach for improving the situation is using lean construction. Lean construction results from the application of a new form of production management to construction. Essential features of lean construction include a clear set of objectives for the delivery process, aimed at maximizing performance for the customer at the project level, concurrent design, construction, and the application of project control throughout the life cycle of the project from design to delivery. An increasing number of construction academics and professionals have been storming the ramparts of conventional construction management in an effort to deliver better value to owners while making real profits. As a result, lean-based tools have emerged and have been successfully applied to simple and complex construction projects. In general, lean construction projects are easier to manage, safer, completed sooner, and cost less and are of better quality. Significant research remains to complete the translation to construction of lean thinking in Egypt. This research will discuss principles, methods, and implementation phases of lean construction showing the waste in construction and how it could be minimized. The Last Planner System technique, which is an important application of the lean construction concepts and methodologies and is more prevalent, proved that it could enhance the construction management practices in various aspects. Also, it is intended to develop methodology for process evaluation and define areas for improvement based on lean approach principles.

  3. Hazard Models From Periodic Dike Intrusions at Kı¯lauea Volcano, Hawai`i

    Science.gov (United States)

    Montgomery-Brown, E. K.; Miklius, A.

    2016-12-01

    The persistence and regular recurrence intervals of dike intrusions in the East Rift Zone (ERZ) of Kı¯lauea Volcano lead to the possibility of constructing a time-dependent intrusion hazard model. Dike intrusions are commonly observed in Kı¯lauea Volcano's ERZ and can occur repeatedly in regions that correlate with seismic segments (sections of rift seismicity with persistent definitive lateral boundaries) proposed by Wright and Klein (USGS PP1806, 2014). Five such ERZ intrusions have occurred since 1983 with inferred locations downrift of the bend in Kı¯lauea's ERZ, with the first (1983) being the start of the ongoing ERZ eruption. The ERZ intrusions occur on one of two segments that are spatially coincident with seismic segments: Makaopuhi (1993 and 2007) and Nāpau (1983, 1997, and 2011). During each intrusion, the amount of inferred dike opening was between 2 and 3 meters. The times between ERZ intrusions for same-segment pairs are all close to 14 years: 14.07 (1983-1997), 14.09 (1997-2011), and 13.95 (1993-2007) years, with the Nāpau segment becoming active about 3.5 years after the Makaopuhi segment in each case. Four additional upper ERZ intrusions are also considered here. Dikes in the upper ERZ have much smaller opening ( 10 cm), and have shorter recurrence intervals of 8 years with more variability. The amount of modeled dike opening during each of these events roughly corresponds to the amount of seaward south flank motion and deep rift opening accumulated in the time between events. Additionally, the recurrence interval of 14 years appears to be unaffected by the magma surge of 2003-2007, suggesting that flank motion, rather than magma supply, could be a controlling factor in the timing and periodicity of intrusions. Flank control over the timing of magma intrusions runs counter to the historical research suggesting that dike intrusions at Kı¯lauea are driven by magma overpressure. This relatively free sliding may have resulted from decreased

  4. Cascading Constrained 2-D Arrays using Periodic Merging Arrays

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Laursen, Torben Vaarby

    2003-01-01

    We consider a method for designing 2-D constrained codes by cascading finite width arrays using predefined finite width periodic merging arrays. This provides a constructive lower bound on the capacity of the 2-D constrained code. Examples include symmetric RLL and density constrained codes...

  5. Spiking mode operation for a uniform-period wiggler

    International Nuclear Information System (INIS)

    Warren, R.W.; Goldstein, J.C.; Newnam, B.E.

    1985-01-01

    The onset of saturation in a uniform-period wiggler has been examined experimentally and through numerical simulations. Models have been constructed that explain the observations in simple and consistent ways. The models are based upon the development of strong frequency and amplitude modulation of the optical wave as a way to increase extraction efficiency and optical power

  6. Existence of extremal periodic solutions for quasilinear parabolic equations

    Directory of Open Access Journals (Sweden)

    Siegfried Carl

    1997-01-01

    bounded domain under periodic Dirichlet boundary conditions. Our main goal is to prove the existence of extremal solutions among all solutions lying in a sector formed by appropriately defined upper and lower solutions. The main tools used in the proof of our result are recently obtained abstract results on nonlinear evolution equations, comparison and truncation techniques and suitably constructed special testfunction.

  7. Effect of various periodic forces on Duffing oscillator

    Indian Academy of Sciences (India)

    ω respectively. However, the Fourier series of all the forces except the force sin ωt considered in our study have various frequencies. The frequencies present in the forces and in the periodic solution confined to the left well alone corresponding to the amplitude f = 0.2 are studied by constructing the Fourier series. 352.

  8. Iraqi architecture in mogul period

    Directory of Open Access Journals (Sweden)

    Hasan Shatha

    2018-01-01

    Full Text Available Iraqi architecture have many periods passed through it until now, each on from these periods have it is architectural style, also through time these styles interacted among us, to creating kind of space forming, space relationships, and architectural elements (detailed treatments, the research problem being from the multi interacted architectural styles causing some of confused of general characteristic to every style, that we could distinguish by it. Research tries to study architecture style through Mogul Conquest to Baghdad. Aim of research follow main characteristic for this architectural style in the Mogul periods on the level of form, elements, and treatments. Research depending on descriptive and analytical all buildings belong to this period, so from analyzing there style by, general form for building, architectural elements, and it architectural treatment, therefore; repeating this procedures to every building we get some similarities, from these similarities we can making conclusion about pure characteristic of the style of these period. Other side, we also discover some Dissimilar in the building periods, these will lead research to make what interacting among styles in this period, after all that we can drew clearly main characteristic of Architectural Style for Mogul Conquest in Baghdad

  9. The Periodic Table in Croatia

    Directory of Open Access Journals (Sweden)

    Raos, N.

    2011-12-01

    Full Text Available The Croatian (Yugoslav Academy of Sciences and Arts was the first academy to elect D. I. Mendeleev as its honorary member (1882, whereas the periodic table of the elements has been taught regularly at the Zagreb University since 1888. The early interest of Croatian chemists in the periodic table should be attributed primarily to their pan-Slavic attitude, particularly as proof that Slavic people were able to produce "their own Newtons" (M. V. Lomonosov and D. I. Mendeleev. Such enthusiastic views, however, did not help in analyzing the contribution of Mendeleev and other scientists to the discovery and development of the periodic table of the elements.

  10. Construction method of pre assembled unit of bolt sphere grid

    Science.gov (United States)

    Hu, L. W.; Guo, F. L.; Wang, J. L.; Bu, F. M.

    2018-03-01

    The traditional construction of bolt sphere grid has many disadvantages, such as high cost, large amount of work at high altitude and long construction period, in order to make up for these shortcomings, in this paper, a new and applicable construction method is explored: setting up local scaffolding, installing the bolt sphere grid starting frame on the local scaffolding, then the pre assembled unit of bolt sphere grid is assembled on the ground, using small hoisting equipment to lift pre assembled unit to high altitude and install. Compared with the traditional installation method, the construction method has strong practicability and high economic efficiency, and has achieved good social and economic benefits.

  11. Accidents in Malaysian construction industry: statistical data and court cases.

    Science.gov (United States)

    Chong, Heap Yih; Low, Thuan Siang

    2014-01-01

    Safety and health issues remain critical to the construction industry due to its working environment and the complexity of working practises. This research attempts to adopt 2 research approaches using statistical data and court cases to address and identify the causes and behavior underlying construction safety and health issues in Malaysia. Factual data on the period of 2000-2009 were retrieved to identify the causes and agents that contributed to health issues. Moreover, court cases were tabulated and analyzed to identify legal patterns of parties involved in construction site accidents. Approaches of this research produced consistent results and highlighted a significant reduction in the rate of accidents per construction project in Malaysia.

  12. Periodic oscillation and exponential stability of delayed CNNs

    Science.gov (United States)

    Cao, Jinde

    2000-05-01

    Both the global exponential stability and the periodic oscillation of a class of delayed cellular neural networks (DCNNs) is further studied in this Letter. By applying some new analysis techniques and constructing suitable Lyapunov functionals, some simple and new sufficient conditions are given ensuring global exponential stability and the existence of periodic oscillatory solution of DCNNs. These conditions can be applied to design globally exponentially stable DCNNs and periodic oscillatory DCNNs and easily checked in practice by simple algebraic methods. These play an important role in the design and applications of DCNNs.

  13. On exponential stability and periodic solutions of CNNs with delays

    Science.gov (United States)

    Cao, Jinde

    2000-03-01

    In this Letter, the author analyses further problems of global exponential stability and the existence of periodic solutions of cellular neural networks with delays (DCNNs). Some simple and new sufficient conditions are given ensuring global exponential stability and the existence of periodic solutions of DCNNs by applying some new analysis techniques and constructing suitable Lyapunov functionals. These conditions have important leading significance in the design and applications of globally stable DCNNs and periodic oscillatory DCNNs and are weaker than those in the earlier works [Phys. Rev. E 60 (1999) 3244], [J. Comput. Syst. Sci. 59 (1999)].

  14. Modeling and designing of variable-period and variable-pole-number undulator

    Directory of Open Access Journals (Sweden)

    I. Davidyuk

    2016-02-01

    Full Text Available The concept of permanent-magnet variable-period undulator (VPU was proposed several years ago and has found few implementations so far. The VPUs have some advantages as compared with conventional undulators, e.g., a wider range of radiation wavelength tuning and the option to increase the number of poles for shorter periods. Both these advantages will be realized in the VPU under development now at Budker INP. In this paper, we present the results of 2D and 3D magnetic field simulations and discuss some design features of this VPU.

  15. Forecasting Canadian nuclear power station construction costs

    International Nuclear Information System (INIS)

    Keng, C.W.K.

    1985-01-01

    Because of the huge volume of capital required to construct a modern electric power generating station, investment decisions have to be made with as complete an understanding of the consequences of the decision as possible. This understanding must be provided by the evaluation of future situations. A key consideration in an evaluation is the financial component. This paper attempts to use an econometric method to forecast the construction costs escalation of a standard Canadian nuclear generating station (NGS). A brief review of the history of Canadian nuclear electric power is provided. The major components of the construction costs of a Canadian NGS are studied and summarized. A database is built and indexes are prepared. Based on these indexes, an econometric forecasting model is constructed using an apparently new econometric methodology of forecasting modelling. Forecasts for a period of 40 years are generated and applications (such as alternative scenario forecasts and range forecasts) to uncertainty assessment and/or decision-making are demonstrated. The indexes, the model, and the forecasts and their applications, to the best of the author's knowledge, are the first for Canadian NGS constructions. (author)

  16. The Sensitivity of Income Polarization - Time, length of accounting periods, equivalence scales, and income definitions

    DEFF Research Database (Denmark)

    Azhar, Hussain

    This study looks at polarization and its components’ sensitivity to assumptions about equivalence scales, income definition, ethical income distribution parameters, and the income accounting period. A representative sample of Danish individual incomes from 1984 to 2002 is utilised. Results show...... that polarization has increased over time, regardless of the applied measure, when the last part of the period is compared to the first part of the period. Primary causes being increased inequality (alienation) and faster income growth among high incomes relative to those in the middle of the distribution....... Increasing the accounting period confirms the reduction in inequality found for shorter periods, but polarization is virtually unchanged, because income group identification increases. Applying different equivalence scales does not change polarization ranking for different years, but identification ranks...

  17. Nuclear reactor constructions

    International Nuclear Information System (INIS)

    Aspden, G.J.

    1980-01-01

    A nuclear reactor construction comprising a reactor core submerged in a pool of liquid metal coolant in a primary vessel which is suspended from the roof structure of a containment vault. Control rods supported from the roof structure are insertable in the core which is carried on a support structure from the wall of the primary vessel. To prevent excessive relaxation of the support structure whereby the control rods would be displaced relative to the core, the support structure incorporates a normally inactive secondary structure designed to become effective in bracing the primary structure against further relaxation beyond a predetermined limit. (author)

  18. Constructive approach to supergravity

    International Nuclear Information System (INIS)

    Milton, K.A.; Urrutia, L.F.; Finkelstein, R.J.

    1980-01-01

    Starting from a first-order formulation of the Lagrangian of noninteracting massless helicity-2 and helicity-3/2 particles, global supersymmetry transformations are deduced. Then, allowing the supersymmetry transformations to become local requires, if supersymmetry is to be maintained, the introduction of a unique primitive interaction through the 'gravitino' stress tensor and torsion. Finally, the imposition of exact supersymmetry invariance leads by a short, constructive process to full supergravity and the complete form of the super-symmetry transformations. In particular, no explicit use is made of general coordinate invariance, and the self-consistency of the gravitational coupling emerges from the local supersymmetry requirement alone. (author)

  19. Reactor PIK construction

    International Nuclear Information System (INIS)

    Konoplev, Kir

    2003-01-01

    The construction work at the 100 MW researches reactor PIK in year 2002 was in progress. The main activity was concentrated on mechanical, ventilation and electrical equipment. Some systems and subsystems are under adjustment. Hydraulic driving gear for beam shutters are finished in installation, rinsing, and adjusting. Regulating rods test assembling was done. On the critical assembly the first reactor fueling was tested to evaluate the starting neutron source intensity and a sufficiency of existing control and instrument board. Mainline of the PIK facility design and neutron parameters are presented. (author)

  20. [Materials for construction sector].

    Science.gov (United States)

    Macchia, C

    2012-01-01

    The construction sector is characterized by high complexity due to several factors. There are a lot of processes within the building sites and they need the use of different materials with the help of appropriate technologies. Traditional materials have evolved and diversified, meanwhile new products and materials appeared and still appear, offering services which meet user needs, but that often involve risks to the health of workers. Research in the field of materials, promoted and carried out at various levels, has led to interesting results, encoded in the form of rules and laws.

  1. Gabor frames by sampling and periodization

    DEFF Research Database (Denmark)

    Søndergaard, Peter Lempel

    2007-01-01

    By sampling the window of Gabor frame for L-2 (R) belonging to Feichtingers algebra S-0 (R), one obtains a Gabor frame for l(2) (Z). In this article we present a survey of results by R. Orr and A.J.E.M. Janssen and extend their ideas to cover interrelations among Gabor frames for the four spaces L......-2 (R), l(2) (Z), L-2 ([O,L]) and C-L. Some new results about the general dual windows with respect to sampling and periodization are presented as well. This theory is used to show a new result of the Kaiblinger type to construct an approximation to the canonical dual window of a Gabor frame for L-2...

  2. Topological imprint for periodic orbits

    International Nuclear Information System (INIS)

    Martín, Jesús San; Moscoso, Ma José; Gómez, A González

    2012-01-01

    The more self-crossing points an orbit has the more complex it is. We introduce the topological imprint to characterize crossing points and focus on the period-doubling cascade. The period-doubling cascade topological imprint determines the topological imprint for orbits in chaotic bands. In addition, there is a closer link between this concept and the braids studied by Lettelier et al (2000 J. Phys. A: Math. Gen. 33 1809–25). (paper)

  3. Minimum period and the gap in periods of Cataclysmic binaries

    International Nuclear Information System (INIS)

    Paczynski, B.; Sienkiewicz, R.

    1983-01-01

    The 81 minute cutoff to the orbital periods of hydrogen-rich cataclysmic binaries is consistent with evolution of those systems being dominated by angular momentum losses due to gravitational radiation. Unfortunately, many uncertainties, mainly poorly known atmospheric opacities below 2000 K, make is physically impossible to verify the quadrupole formula for gravitational radiation by using the observed cutoff at 81 minutes. The upper boundary of the gap in orbital periods observed at about 3 hours is almost certainly due to enhanced angular momentum losses from cataclysmic binaries which have longer periods. The physical mechanism of those losses is not identified, but a possible importance of stellar winds is pointed out. The lower boundary of the gap may be explained with the oldest cataclysmic binaries, whose periods evolved past the minimum at 81 minutes and reached the value of 2 hours within about 12 x 10 9 years after the binary had formed. Those binaries should have secondary components of only 0.02 solar masses, and their periods could be used to estimate ages of the oldest cataclysmic stars, and presumably the age of Galaxy. An alternative explanation for the gap requires that binaries should be detached while crossing the gap. A possible mechanism for this phenomenon is discussed. It requires the secondary components to be about 0.2 solar masses in the binaries just below the gap

  4. Assessing the sustainable construction of large construction companies in Malaysia

    Science.gov (United States)

    Adewale, Bamgbade Jibril; Mohammed, Kamaruddeen Ahmed; Nasrun, Mohd Nawi Mohd

    2016-08-01

    Considering the increasing concerns for the consideration of sustainability issues in construction project delivery within the construction industry, this paper assesses the extent of sustainable construction among Malaysian large contractors, in order to ascertain the level of the industry's impacts on both the environment and the society. Sustainable construction explains the construction industry's responsibility to efficiently utilise the finite resources while also reducing construction impacts on both humans and the environment throughout the phases of construction. This study used proportionate stratified random sampling to conduct a field study with a sample of 172 contractors out of the 708 administered questionnaires. Data were collected from large contractors in the eleven states of peninsular Malaysia. Using the five-level rating scale (which include: 1= Very Low; 2= Low; 3= Moderate; 4= High; 5= Very High) to describe the level of sustainable construction of Malaysian contractors based on previous studies, statistical analysis reveals that environmental, social and economic sustainability of Malaysian large contractors are high.

  5. Innovations in nuclear concrete constructions

    International Nuclear Information System (INIS)

    Tatum, C.B.

    1983-01-01

    The technical requirements and scope of concrete work on nuclear projects present significant engineering and construction challenges. These demands represent the extremes in many areas of construction operations. In meeting these challenges, engineering and construction forces have developed several innovations which can be beneficially applied to other types of construction. Innovative approaches in the general categories of engineering scope, construction input to engineering, work planning, special methods and techniques, and satisfaction of quality assurance requirements are given in this paper. The transfer of this technology to other segments of the construction industry will improve overall performance by avoiding the problem areas encountered on nuclear projects

  6. Estimation of construction waste generation and management in Thailand.

    Science.gov (United States)

    Kofoworola, Oyeshola Femi; Gheewala, Shabbir H

    2009-02-01

    This study examines construction waste generation and management in Thailand. It is estimated that between 2002 and 2005, an average of 1.1 million tons of construction waste was generated per year in Thailand. This constitutes about 7.7% of the total amount of waste disposed in both landfills and open dumpsites annually during the same period. Although construction waste constitutes a major source of waste in terms of volume and weight, its management and recycling are yet to be effectively practiced in Thailand. Recently, the management of construction waste is being given attention due to its rapidly increasing unregulated dumping in undesignated areas, and recycling is being promoted as a method of managing this waste. If effectively implemented, its potential economic and social benefits are immense. It was estimated that between 70 and 4,000 jobs would have been created between 2002 and 2005, if all construction wastes in Thailand had been recycled. Additionally it would have contributed an average savings of about 3.0 x 10(5) GJ per year in the final energy consumed by the construction sector of the nation within the same period based on the recycling scenario analyzed. The current national integrated waste management plan could enhance the effective recycling of construction and demolition waste in Thailand when enforced. It is recommended that an inventory of all construction waste generated in the country be carried out in order to assess the feasibility of large scale recycling of construction and demolition waste.

  7. Probabilistic pathway construction.

    Science.gov (United States)

    Yousofshahi, Mona; Lee, Kyongbum; Hassoun, Soha

    2011-07-01

    Expression of novel synthesis pathways in host organisms amenable to genetic manipulations has emerged as an attractive metabolic engineering strategy to overproduce natural products, biofuels, biopolymers and other commercially useful metabolites. We present a pathway construction algorithm for identifying viable synthesis pathways compatible with balanced cell growth. Rather than exhaustive exploration, we investigate probabilistic selection of reactions to construct the pathways. Three different selection schemes are investigated for the selection of reactions: high metabolite connectivity, low connectivity and uniformly random. For all case studies, which involved a diverse set of target metabolites, the uniformly random selection scheme resulted in the highest average maximum yield. When compared to an exhaustive search enumerating all possible reaction routes, our probabilistic algorithm returned nearly identical distributions of yields, while requiring far less computing time (minutes vs. years). The pathways identified by our algorithm have previously been confirmed in the literature as viable, high-yield synthesis routes. Prospectively, our algorithm could facilitate the design of novel, non-native synthesis routes by efficiently exploring the diversity of biochemical transformations in nature. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. Probabilistic liver atlas construction.

    Science.gov (United States)

    Dura, Esther; Domingo, Juan; Ayala, Guillermo; Marti-Bonmati, Luis; Goceri, E

    2017-01-13

    Anatomical atlases are 3D volumes or shapes representing an organ or structure of the human body. They contain either the prototypical shape of the object of interest together with other shapes representing its statistical variations (statistical atlas) or a probability map of belonging to the object (probabilistic atlas). Probabilistic atlases are mostly built with simple estimations only involving the data at each spatial location. A new method for probabilistic atlas construction that uses a generalized linear model is proposed. This method aims to improve the estimation of the probability to be covered by the liver. Furthermore, all methods to build an atlas involve previous coregistration of the sample of shapes available. The influence of the geometrical transformation adopted for registration in the quality of the final atlas has not been sufficiently investigated. The ability of an atlas to adapt to a new case is one of the most important quality criteria that should be taken into account. The presented experiments show that some methods for atlas construction are severely affected by the previous coregistration step. We show the good performance of the new approach. Furthermore, results suggest that extremely flexible registration methods are not always beneficial, since they can reduce the variability of the atlas and hence its ability to give sensible values of probability when used as an aid in segmentation of new cases.

  9. Construction of Monju

    International Nuclear Information System (INIS)

    Yoshino, Kenichi; Ogiso, Zenichi; Nakamura, Kazuo; Nishida, Masaaki; Tateishi, Yoshinori; Mishima, Tsuyoshi

    1994-01-01

    The construction works was started in January, 1983. The main works can be divided into (1) the construction of the roads to the site including the repair of the prefectural road, (2) the preparation of the land for temporary installation outside the site, (3) the creation of the site, the excavation for building foundations, the change of the stream in the site, and the land side works of water intake and discharge facilities, (4) the sea area works of bank revetment, breakwaters and unloading quay, and (5) the manufacture of caissons and blocks in the Technoport Fukui about 60 km distant from the site. The main buildings are those for the reactor, reactor auxiliaries, maintenance and waste treatment, diesel engines, and the turbine. The aseismatic structure, the coolant temperature if it leaks were the main considerations. The manufacture, transport and installation of machinery and equipment are reported. The sodium of about 1700 t was imported from France. The MOX fuel for initial charge was produced, and the pellets were filled smoothly. (K.I.)

  10. Constructal vascularized structures

    Science.gov (United States)

    Cetkin, Erdal

    2015-06-01

    Smart features such as self-healing and selfcooling require bathing the entire volume with a coolant or/and healing agent. Bathing the entire volume is an example of point to area (or volume) flows. Point to area flows cover all the distributing and collecting kinds of flows, i.e. inhaling and exhaling, mining, river deltas, energy distribution, distribution of products on the landscape and so on. The flow resistances of a point to area flow can be decreased by changing the design with the guidance of the constructal law, which is the law of the design evolution in time. In this paper, how the flow resistances (heat, fluid and stress) can be decreased by using the constructal law is shown with examples. First, the validity of two assumptions is surveyed: using temperature independent Hess-Murray rule and using constant diameter ducts where the duct discharges fluid along its edge. Then, point to area types of flows are explained by illustrating the results of two examples: fluid networks and heating an area. Last, how the structures should be vascularized for cooling and mechanical strength is documented. This paper shows that flow resistances can be decreased by morphing the shape freely without any restrictions or generic algorithms.

  11. Scene construction in schizophrenia.

    Science.gov (United States)

    Raffard, Stéphane; D'Argembeau, Arnaud; Bayard, Sophie; Boulenger, Jean-Philippe; Van der Linden, Martial

    2010-09-01

    Recent research has revealed that schizophrenia patients are impaired in remembering the past and imagining the future. In this study, we examined patients' ability to engage in scene construction (i.e., the process of mentally generating and maintaining a complex and coherent scene), which is a key part of retrieving past experiences and episodic future thinking. 24 participants with schizophrenia and 25 healthy controls were asked to imagine new fictitious experiences and described their mental representations of the scenes in as much detail as possible. Descriptions were scored according to various dimensions (e.g., sensory details, spatial reference), and participants also provided ratings of their subjective experience when imagining the scenes (e.g., their sense of presence, the perceived similarity of imagined events to past experiences). Imagined scenes contained less phenomenological details (d = 1.11) and were more fragmented (d = 2.81) in schizophrenia patients compared to controls. Furthermore, positive symptoms were positively correlated to the sense of presence (r = .43) and the perceived similarity of imagined events to past episodes (r = .47), whereas negative symptoms were negatively related to the overall richness of the imagined scenes (r = -.43). The results suggest that schizophrenic patients' impairments in remembering the past and imagining the future are, at least in part, due to deficits in the process of scene construction. The relationships between the characteristics of imagined scenes and positive and negative symptoms could be related to reality monitoring deficits and difficulties in strategic retrieval processes, respectively. Copyright 2010 APA, all rights reserved.

  12. Microgripper construction kit

    Science.gov (United States)

    Gengenbach, Ulrich K.; Hofmann, Andreas; Engelhardt, Friedhelm; Scharnowell, Rudolf; Koehler, Bernd

    2001-10-01

    A large number of microgrippers has been developed in industry and academia. Although the importance of hybrid integration techniques and hence the demand for assembly tools grows continuously a large part of these developments has not yet been used in industrial production. The first grippers developed for microassembly were basically vacuum grippers and downscaled tweezers. Due to increasingly complex assembly tasks more and more functionality such as sensing or additional functions such as adhesive dispensing has been integrated into gripper systems over the last years. Most of these gripper systems are incompatible since there exists no standard interface to the assembly machine and no standard for the internal modules and interfaces. Thus these tools are not easily interchangeable between assembly machines and not easily adaptable to assembly tasks. In order to alleviate this situation a construction kit for modular microgrippers is being developed. It is composed of modules with well defined interfaces that can be combined to build task specific grippers. An abstract model of a microgripper is proposed as a tool to structure the development of the construction kit. The modular concept is illustrated with prototypes.

  13. Periodically driven random quantum spin chains: real-space renormalization for Floquet localized phases

    Science.gov (United States)

    Monthus, Cécile

    2017-07-01

    When random quantum spin chains are submitted to some periodic Floquet driving, the eigenstates of the time-evolution operator over one period can be localized in real space. For the case of periodic quenches between two Hamiltonians (or periodic kicks), where the time-evolution operator over one period reduces to the product of two simple transfer matrices, we propose a block-self-dual renormalization procedure to construct the localized eigenstates of the Floquet dynamics. We also discuss the corresponding strong disorder renormalization procedure, that generalizes the RSRG-X procedure to construct the localized eigenstates of time-independent Hamiltonians.

  14. Commuting periodic operators and the periodic Wigner function

    International Nuclear Information System (INIS)

    Zak, J

    2004-01-01

    Commuting periodic operators (CPO) depending on the coordinate x-hat and the momentum p-hat operators are defined. The CPO are functions of the two basic commuting operators exp(i x-hat 2π/a) and exp(i/h p-hat a), with a being an arbitrary constant. A periodic Wigner function (PWF) w(x, p) is defined and it is shown that it is applicable in a normal expectation value calculation to the CPO, as done in the original Wigner paper. Moreover, this PWF is non-negative everywhere, and it can therefore be interpreted as an actual probability distribution. The PWF w(x, p) is shown to be given as an expectation value of the periodic Dirac delta function in the phase plane. (letter to the editor)

  15. Nanopublication beyond the sciences: the PeriodO period gazetteer

    Directory of Open Access Journals (Sweden)

    Patrick Golden

    2016-02-01

    Full Text Available The information expressed in humanities datasets is inextricably tied to a wider discursive environment that is irreducible to complete formal representation. Humanities scholars must wrestle with this fact when they attempt to publish or consume structured data. The practice of “nanopublication,” which originated in the e-science domain, offers a way to maintain the connection between formal representations of humanities data and its discursive basis. In this paper we describe nanopublication, its potential applicability to the humanities, and our experience curating humanities nanopublications in the PeriodO period gazetteer.

  16. Fatal accidents in nighttime vs. daytime highway construction work zones.

    Science.gov (United States)

    Arditi, David; Lee, Dong-Eun; Polat, Gul

    2007-01-01

    Awareness about worker safety in nighttime construction has been a major concern because it is believed that nighttime construction creates hazardous work conditions. However, only a few studies provide valuable comparative information about accident characteristics of nighttime and daytime highway construction activities. This study investigates fatal accidents that occurred in Illinois highway work zones in the period 1996-2001 in order to determine the safety differences between nighttime and daytime highway construction. The lighting and weather conditions were included into the study as control parameters to see their effects on the frequency of fatal accidents occurring in work zones. According to this study, there is evidence that nighttime construction is more hazardous than daytime construction. The inclusion of a weather parameter into the analysis has limited effect on this finding. The study justifies establishing an efficient work zone accident reporting system and taking all necessary measures to enhance safety in nighttime work zones.

  17. Construction inspection manual of procedures

    Science.gov (United States)

    2009-01-01

    This manual provides highway construction personnel with relevant, practical information in order to perform accurate inspections and provide relevant construction procedural information for the various roadway and structures items of work. It is the...

  18. Structural Impact of Construction Loads

    Science.gov (United States)

    2012-08-01

    Numerous bridge construction accidents have occurred across the country because of construction loadings, which are an underemphasized : topic in many DOT specifications and design manuals. Bridge girders are least stable when they are subjected to c...

  19. Priorities in Construction IT Research

    DEFF Research Database (Denmark)

    Gaarslev, Axel

    1999-01-01

    Gives the results of a survey of the use and needs of research in IT in relation to construction......Gives the results of a survey of the use and needs of research in IT in relation to construction...

  20. Construction of SPring-8 LINAC

    International Nuclear Information System (INIS)

    Yokomizo, Hideaki; Yoshikawa, Hiroshi; Suzuki, Shinsuke; Yanagida, Ken-ichi; Mizuno, Akihiko; Hori, Toshihiko; Tamezane, Kenji; Kodera, Masahiko; Sakaki, Hironao; Mashiko, Katsuo

    1993-01-01

    Construction of the linac building has been started in February 1993. The components of the linac are under manufacturing. The preinjector of linac was already constructed and temporarily installed in Tokai Establishment in order to test the beam quality. (author)

  1. Periodic testing in operative action

    International Nuclear Information System (INIS)

    Larm, T.

    2005-01-01

    Periodic testing forms a remarkable part of the regular work tasks of the shift crew. Testing is generally carried out beside the daily monitoring and control work. Even remarkable plant related differences may occur in the procedures and routines used in periodic testing. The goal is still always the same, to regularly ensure that the systems and equipment are in working order according to their design. This presentation studies with examples the execution and scope of periodic testing as well as the routines and procedures used in the testing in Loviisa power plant. The presentation is based on the testing procedures of Loviisa power plant and the aim is not to compare them to the procedures of other plants. The scope of periodic testing has increased and the routines and procedures have been developed as the operation experience has increased. The assessment of the need of periodic testing and the consideration of the practical execution possibilities should be a part of the plant's planning phase as a part of the planning process. (orig.)

  2. Quantitative Identification of Construction Risk

    OpenAIRE

    Kasprowicz T.

    2017-01-01

    Risks pertaining to construction work relate to situations in which various events may randomly change the duration and cost of the project or worsen its quality. Because of possible significant changes of random events, favorable, moderate, and difficult conditions of construction work are considered. It is the first stage of the construction risk analysis. The probabilistic parameters of construction are identified and described by using the design characteristics model of the structure and...

  3. Bond yield curve construction

    Directory of Open Access Journals (Sweden)

    Kožul Nataša

    2014-01-01

    Full Text Available In the broadest sense, yield curve indicates the market's view of the evolution of interest rates over time. However, given that cost of borrowing it closely linked to creditworthiness (ability to repay, different yield curves will apply to different currencies, market sectors, or even individual issuers. As government borrowing is indicative of interest rate levels available to other market players in a particular country, and considering that bond issuance still remains the dominant form of sovereign debt, this paper describes yield curve construction using bonds. The relationship between zero-coupon yield, par yield and yield to maturity is given and their usage in determining curve discount factors is described. Their usage in deriving forward rates and pricing related derivative instruments is also discussed.

  4. Culture in constructive remembering

    DEFF Research Database (Denmark)

    Wagoner, Brady

    2012-01-01

    an alternative temporal metaphor of remembering as ‘construction’. If we push his metaphor further—with the help of cultural psychology—we can say memory construction is done by agents using cultural ‘tools’ such as language and narrative. In this chapter, Bartlett’s theory is contextualized, elucidated......, critiqued and developed with the help of a number of other thinkers. The ultimate aim of the chapter is to go beyond Bartlett and arrive at a thoroughgoing culturally inclusive psychological theory of remembering. Though Bartlett clearly situated remembering within a social process, he did not provide......The present chapter explores novel ways of thinking about what it means to remember and how precisely culture is involved in this process. Since Plato, the dominant metaphor for conceptualizing memory has been that of a spatial ‘storage’. In contrast to this, Frederic Bartlett advanced...

  5. Constructing visual representations

    DEFF Research Database (Denmark)

    Huron, Samuel; Jansen, Yvonne; Carpendale, Sheelagh

    2014-01-01

    tangible building blocks. We learned that all participants, most of whom had little experience in visualization authoring, were readily able to create and talk about their own visualizations. Based on our observations, we discuss participants’ actions during the development of their visual representations......The accessibility of infovis authoring tools to a wide audience has been identified as a major research challenge. A key task in the authoring process is the development of visual mappings. While the infovis community has long been deeply interested in finding effective visual mappings......, comparatively little attention has been placed on how people construct visual mappings. In this paper, we present the results of a study designed to shed light on how people transform data into visual representations. We asked people to create, update and explain their own information visualizations using only...

  6. TOTEM Construction Complete

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    The winter technical stop saw the final steps of the installation of the TOTEM experiment. After 8 years of development, the inelastic telescope T1 was successfully installed inside CMS at both sides of the interaction point. This detector joins the previously installed inelastic telescope T2 and the Roman Pots (147m and 220m from the CMS interaction point) to study both elastic and inelastic proton scattering.   The Genova team who designed and built the detector in front of the '+' arm of the T1 telescope after final insertion. All the detector chambers were assembled at the Petersburg Nuclear Physics Institute, Gatchina, Russia. Major contributions to the construction of the support structure and the installation process came from CERN. “Installing the T1 detector was an important milestone for TOTEM,” says Joachim Baechler, Technical Coordinator for TOTEM. Enrico Robutti from Genova, responsible for the T1 project, added: "The T1 detector was carefully installed ...

  7. Perturbative and constructive renormalization

    International Nuclear Information System (INIS)

    Veiga, P.A. Faria da

    2000-01-01

    These notes are a survey of the material treated in a series of lectures delivered at the X Summer School Jorge Andre Swieca. They are concerned with renormalization in Quantum Field Theories. At the level of perturbation series, we review classical results as Feynman graphs, ultraviolet and infrared divergences of Feynman integrals. Weinberg's theorem and Hepp's theorem, the renormalization group and the Callan-Symanzik equation, the large order behavior and the divergence of most perturbation series. Out of the perturbative regime, as an example of a constructive method, we review Borel summability and point out how it is possible to circumvent the perturbation diseases. These lectures are a preparation for the joint course given by professor V. Rivasseau at the same school, where more sophisticated non-perturbative analytical methods based on rigorous renormalization group techniques are presented, aiming at furthering our understanding about the subject and bringing field theoretical models to a satisfactory mathematical level. (author)

  8. Skin Cut Construction

    DEFF Research Database (Denmark)

    2017-01-01

    projects - among others - from ARC are included: Soft Structures builds upon of a series of experimental use of EPS hot wire cutting, where the EPS eventually act as formwork for concrete casting. The processing of the EPS is distinct and delimited by the behaviour and form of both the robot and tool...... of steel and concrete makes it a reliable approach to many challenges in the realisation of buildings. Rebar Inside Out attempts to rethink the possibilities of the reinforced concrete composite starting from its inside. This means starting with the reinforcing steel, the production and shaping of this......, and then through that process build a workflow for the production of the concrete composite. It also means letting the steel out of the concrete, thereby positioning the two materials in a transnational relationship between steel construction and concrete composite....

  9. Derailed self-constructions

    DEFF Research Database (Denmark)

    Sørensen, Niels Ulrik; Nielsen, Jens Christian

    2017-01-01

    The chapter focuses on the construction of self amongst a group of young boys in Denmark who have had experience with eating disorders, self- harm, loneli-ness and other manifestations of a lack of well- being. At first glance, these manifestations of a lack of well- being seem rather distinct...... and incomparable, but they have in common the fact that the young boys who have had these experiences say that they are due to personal faults and imperfections. In other words, they are related to problematizing thematizations of the self. In the chapter, we investigate these problematizing thematizations...... and explore the ways that young boys understand and experience the self, and how they link this self to their lack of well-being. As will become apparent, fear of marginalization seems to be an important part of this connection: The young boys are struggling to live up to expectations in an increasingly...

  10. Environmentally friendly road construction

    Directory of Open Access Journals (Sweden)

    A.I. Essawy

    2013-06-01

    Full Text Available Environmental pollution is a major problem in developing countries like Egypt. Reuse of waste polymers is considered an attractive solution for environmental white pollution and reducing of the costs of road pavement and maintenance. This research aims to prepare environmentally friendly hot mix asphalt (HMA for paving using some industrial wastes as polypropylene and polyester fibers. The solid materials in the mix include normal and highly porous aggregates. 5% and 10% of waste polymers by weight of the asphalt were used to prepare special binders. The samples were tested for their physical properties, chemical properties, aging, scanning electron microscopy (SEM and thermo-gravimetric analysis (TGA. The results revealed that the prepared HMA using 5% of waste polymer had high performance as compared to the ordinary one and the waste polymer could be used in road construction.

  11. Self-reliance and innovation to improve the localization ability of nuclear power construction

    International Nuclear Information System (INIS)

    Wu Chongming

    2008-01-01

    Construction is a crucial link in the course of design, site selection, construction and operation for a nuclear power plant. The quality during construction directly affects the nuclear safety. And the construction quality involves various aspects including quality culture, feasibility of construction technique, quality assurance, and quality control. Through technical management innovation, great achievements have been made in the civil construction of Unit 3 of Qinshan II Extension Project. As a result, the construction period was shortened and the concrete quality reached the fairfaced concrete standard. (authors)

  12. Constructing passive houses

    Energy Technology Data Exchange (ETDEWEB)

    Oehler, S. [Oehler Faigle Archkom Solar Architektur, Bretten (Germany)

    2005-07-01

    Everybody can learn to build energy-efficient. It needs theoretical and practical experience. 1997 we built the first freestanding Passive House in Europe, the Passive House Oehler. There had been a lot of questions, starting with the insecurity, whether the calculation program of the Passive House Institute, the PHPP, is working properly in our case. Nobody knew at that time because nobody tried it out before. It took us a lot of time to find out and every detail of the construction hat to be invented to meet the very high demand of thermal quality. All the following houses needed less time and had fewer open questions, adding one piece of experience with every building. 2002 we realised the biggest Passive House, the office building Energon Ulm with 420 working spaces. In the meantime we have learned a lot like how to produce prefabricated timber elements for the facades, providing good insulation, air tightness and avoiding serious thermal bridges. We have proofed, that any kind of building type can be a Passive House. And with increasing experience the freedom of design and construction is growing. Even the economical efficiency increased. The Energon Ulm is providing a much better indoor climate than any other office building and was build 10 % cheaper than an average German office building. At present the Passive House Standard is the most efficient solution for the user to live in the desired comfort zone between 20 C and 25 C. This zone of individual feeling-well can be described with the term ''operative temperature''. This term is defined by factors like air temperature, radiation temperature of warm and cold surfaces, air speed and humidity. The result of all these factors has to be within 18 C to 25 C without accepting one of the factors getting extreme.

  13. Constructing Data Curation Profiles

    Directory of Open Access Journals (Sweden)

    Michael Witt

    2009-12-01

    Full Text Available This paper presents a brief literature review and then introduces the methods, design, and construction of the Data Curation Profile, an instrument that can be used to provide detailed information on particular data forms that might be curated by an academic library. These data forms are presented in the context of the related sub-disciplinary research area, and they provide the flow of the research process from which these data are generated. The profiles also represent the needs for data curation from the perspective of the data producers, using their own language. As such, they support the exploration of data curation across different research domains in real and practical terms. With the sponsorship of the Institute of Museum and Library Services, investigators from Purdue University and the University of Illinois interviewed 19 faculty subjects to identify needs for discovery, access, preservation, and reuse of their research data. For each subject, a profile was constructed that includes information about his or her general research, data forms and stages, value of data, data ingest, intellectual property, organization and description of data, tools, interoperability, impact and prestige, data management, and preservation. Each profile also presents a specific dataset supplied by the subject to serve as a concrete example. The Data Curation Profiles are being published to a public wiki for questions and discussion, and a blank template will be disseminated with guidelines for others to create and share their own profiles. This study was conducted primarily from the viewpoint of librarians interacting with faculty researchers; however, it is expected that these findings will complement a wide variety of data curation research and practice outside of librarianship and the university environment.

  14. Construction Management of Electromechanical Engineering Project in Petrochemical Construction

    Directory of Open Access Journals (Sweden)

    Xi Tao

    2017-03-01

    Full Text Available Petrochemical industry as a basic industry, occupies a pivotal position in the national economy, with the continuous development of science and technology, electromechanical automation in the petrochemical industry has been widely used to save a lot of labor but also greatly improve the oil Chemical industry production efficiency. Therefore, in the construction of petrochemical industry, mechanical and electrical engineering as part of it. It plays a vital role. Petrochemical industry with the production of high temperature and high pressure and flammable and explosive gas, can strengthen the construction of mechanical and electrical engineering specialization and construction management of scientific, has become the relationship between the smooth development of mechanical and electrical engineering and engineering quality of the key, A direct impact on the petrochemical construction of the overall construction quality. To this end, it is necessary for the construction of petrochemical construction of electromechanical engineering construction management to promote the construction of mechanical and electrical engineering management level gradually increased. This article on the machine Electric engineering project construction management were discussed with a view to the petrochemical construction in the relevant aspects of the need to provide reference for reference.

  15. Geotextiles in Flexible Pavement Construction

    Science.gov (United States)

    Alungbe, Gabriel D.

    2004-01-01

    People everywhere in the developed world regularly drive on paved roads. Learning about the construction techniques and materials used in paving benefits technology and construction students. This article discusses the use of geosynthetic textiles in pavement construction. It presents background on pavements and describes geotextiles and drainage…

  16. Design of Long Period Pseudo-Random Sequences from the Addition of -Sequences over

    Directory of Open Access Journals (Sweden)

    Ren Jian

    2004-01-01

    Full Text Available Pseudo-random sequence with good correlation property and large linear span is widely used in code division multiple access (CDMA communication systems and cryptology for reliable and secure information transmission. In this paper, sequences with long period, large complexity, balance statistics, and low cross-correlation property are constructed from the addition of -sequences with pairwise-prime linear spans (AMPLS. Using -sequences as building blocks, the proposed method proved to be an efficient and flexible approach to construct long period pseudo-random sequences with desirable properties from short period sequences. Applying the proposed method to , a signal set is constructed.

  17. Periodicity and repeatability in data

    Science.gov (United States)

    Southwood, D.

    Using magnetic data from the first two years in Saturn orbit, the basic periodicity of apparent is examined with the aim of elucidating the `cam' shaft model of Espinosa et al. (2003) identifying the nature of the `cam' and giving a definitive period for its rotation. An initial hypothesis, supported by the spectral analysis of analysis of the first 8 months in orbit Gianpieri et al. (2006), is made that the source of the period is linked to something inside the planet and therefore that the source inertia means that the period effectively does not change over the 2 years. Moreover one expects that the source phase is fixed. Using this approach, not only can the period identified by spectral analysis (647.1 + 0.6 min.) be verified but also by phase analysis between successive passes over the 2 years the period can be refined to 647.6 + 0.1 min. The signal itself is remarkably reproducible from pass to pass. It appears in all three components of the field and its polarisation is unambiguously not attributable to direct detection of an internal field. Not only does the signal not decay rapidly with distance from the planet, but although it has the m=1 symmetry of a tilted dipole, the field lines diverge from the planet indicating an exterior source. This feature led to the `cam' model. The polarisation and comparisons of passes with different latitude profiles show a surprising north-south symmetry in the azimuthal field. The absence of asymmetry with respect to the magnetic equator rules out a direct magnetospheric-ionospheric interaction source. Accordingly, it is proposed that the basic `cam' effect is generated by a single hemisphere anomaly which creates hemisphere to hemisphere field aligned currents. The existence of Saturn phase related anomaly appears to produce a basic asymmetry in the inner magnetosphere that sets the phase of both an inflowing and outflowing sector in a rotating circulation system.

  18. ATLAS: Adjuvant Tamoxifen Longer Against Shorter

    Science.gov (United States)

    1998-09-01

    largely tunaffected by other these 30 000 women during about 10 years of follow-up patient characteristics or treatments. were 21% (SD 3), 29% (SD 2...for both types of mosted to stop part of the eduon y epatient . most of them did stop, part of the reduction in the The right side of figure 4...patient characteristics (e.g. high/ low-risk, ER+/ER-, pre/post-menopausal) recorded at entry. Other trials of tamoxifen duration The Atlas collaboration

  19. Movement and touch make plants shorter

    NARCIS (Netherlands)

    Heuvelink, E.; Kierkels, T.

    2017-01-01

    Plants in the greenhouse are increasingly on the move. More attention is being paid to air circulation and mobile cultivation is on the rise. Research shows that movement and touch (also as plants rub against each other) slow down growth. That can be frustrating but you can also use it to your

  20. An improved test for periodicity

    International Nuclear Information System (INIS)

    Davies, S.R.

    1990-01-01

    I discuss two widely used methods of testing for periodicity, phase dispersion minimization and epoch-folding. Using an analysis of variance approach, I demonstrate the close relationship between these two methods. I also show that the significance test sometimes used in phase dispersion minimization is statistically inaccurate, and that the test used in epoch-folding is an approximation valid only for large sample sizes. I propose a new test statistic, applicable to either epoch-folding or PDM, which is statistically sound for all sample sizes, and which is also more sensitive to periodicity than the test statistics previously used with these two methods. (author)