The clinical and neurophysiological characteristics of the deja vu phenomenon in epilepsy

Directory of Open Access Journals (Sweden)

P. N. Vlasov

2012-01-01

Full Text Available Objective: to study the clinical and neurophysiological characteristics of the deja vu phenomenon in epilepsy. Patients and methods. The manifestations of the dВjЕ vu phenomenon were compared in 154 examinees in two groups: 1 139 healthy individuals and 2 25 patients with epilepsy (mean age 25.17±9.19 years; women, 63.2% The characteristics of the phenomenon were determined, by questioning the examinees; 12—16-hour ambulatory electroencephalogram (EEG monitoring was made. Results. The deja vu phenomenon occurred with cryptogenic and symptomatic focal epilepsy with equal frequency; however, the phenomenon was also seen in the idiopathic generalized form of the latter and could be concurrent virtually with any types of seizures and observed as an individual seizure and in the structure of a partial and secondarily generalized seizure. In epileptic patients, the main clinical characteristics of the deja vu vu phenomenon are its frequency, fear before its onset, and emotional coloring. The most important criterion is a change in the characteristics of deja vu vu: prolongation, more frequencies, and the emergence of negative emotions. On EEG, the phenomenon was characterized by the onset of polyspike activity in the right temporal leads and, in some cases, ended with slow-wave, theta-delta activity in the right hemisphere.

Effect of hindlimb unweighting on single soleus fiber maximal shortening velocity and ATPase activity

Science.gov (United States)

Mcdonald, K. S.; Fitts, R. H.

1993-01-01

The effect of hindlimb unweighting (HU) for 1 to 3 wks on the shortening velocity of a soleus fiber, its ATPase content, and the relative contents of the slow and fast myosin was investigated by measuring fiber force, V(0), ATPase activity, and myosin content in SDS protein profiles of a single rat soleus fiber suspended between a motor arm and a transducer. It was found that HU induces a progressive increase in fiber V(0) that is likely caused, at least in part, by an increase in the fiber's myofibrillar ATPase activity. The HU-induced increases in V(0) and ATPase were associated with the presence of a greater percentage of fast type IIa fibers. However, a large population of fibers after 1, 2, and 3 wks of HU showed increases in V(0) and ATPase but displayed the same myosin protein profile on SDS gels as control fibers.

Tippdisain Hank Vu'lt Urbana teostuses

Index Scriptorium Estoniae

1999-01-01

Vietnamis sündinud, Ameerika Ühendriikides Kalifornias töötav arhitektiharidusega mööblidisainer Hank Vu teeb lihtsat, funktsionaalset, abstraktselt orgaanilise vormiga mööblit. 6 illustratsiooni

Bioloģisko aktīvu uzskaite SIA "Lielvircava Agro"

OpenAIRE

Laščenko, Jeļena

2010-01-01

Latvijā bioloģisko aktīvu uzskaites problemātika ir neizpētīts jautājums, gan no zinātnisko pētījumu, gan no regulējuma aspekta. Darba mērķis ir izpētīt SIA „Lielvircava AGRO” piederošo bioloģisko aktīvu uzskaites īpatnības un izstrādāt priekšlikumus bioloģisko aktīvu uzskaites pilnveidošanai. Darba mērķi un uzdevumi tiek atspoguļoti darba divās loģiski saistītās nodaļās, secinājumos un priekšlikumos, literatūras sarakstā, kā arī pielikumos. Darba pirmā nodaļā tiek skaidrots bioloģis...

Unveiling the mystery of déjà vu: The structural anatomy of déjà vu

Czech Academy of Sciences Publication Activity Database

Brázdil, M.; Mareček, R.; Urbánek, Tomáš; Kašpárek, T.; Mikl, M.; Rektor, I.; Zeman, A.

2012-01-01

Roč. 48, č. 9 (2012), s. 1240-1243 ISSN 0010-9452 Institutional support: RVO:68081740 Keywords : déjà vu * temporal lobe epilepsy * neuroanatomy Subject RIV: FH - Neurology Impact factor: 6.161, year: 2012

Deja vu: a database of highly similar citations in the scientific literature.

Science.gov (United States)

Errami, Mounir; Sun, Zhaohui; Long, Tara C; George, Angela C; Garner, Harold R

2009-01-01

In the scientific research community, plagiarism and covert multiple publications of the same data are considered unacceptable because they undermine the public confidence in the scientific integrity. Yet, little has been done to help authors and editors to identify highly similar citations, which sometimes may represent cases of unethical duplication. For this reason, we have made available Déjà vu, a publicly available database of highly similar Medline citations identified by the text similarity search engine eTBLAST. Following manual verification, highly similar citation pairs are classified into various categories ranging from duplicates with different authors to sanctioned duplicates. Déjà vu records also contain user-provided commentary and supporting information to substantiate each document's categorization. Déjà vu and eTBLAST are available to authors, editors, reviewers, ethicists and sociologists to study, intercept, annotate and deter questionable publication practices. These tools are part of a sustained effort to enhance the quality of Medline as 'the' biomedical corpus. The Déjà vu database is freely accessible at http://spore.swmed.edu/dejavu. The tool eTBLAST is also freely available at http://etblast.org.

The Danger of Deja Vu: Why the Iraq Surge is Not a Lesson for Afghanistan

Science.gov (United States)

2010-01-01

JAN 2010 2. REPORT TYPE 3. DATES COVERED 00-12-2009 to 00-01-2010 4. TITLE AND SUBTITLE The danger of deja vu . Why the Iraq surge is not a lesson...of five brigade combat teams — eerily mim- icked the surge number for Iraq. And there was more déjà vu when our senior civilian and military leaders...Department. PERSPECTIVES The danger of déjà vu Why the Iraq surge is not a lesson for Afghanistan BY COL. CHARLES D. ALLEN (RET.) The thing we take hold of

Anatomy of Deja Vu in Temporal Lobe Epilepsy

OpenAIRE

J Gordon Millichap

1994-01-01

Sixteen patients, ages 16 to 32 years, implanted with depth electrodes at Hopital Saint-Anne, Paris, France, had experienced a dreamy state (deja-vu - deja vecu, memories of complete scenes, or vague reminiscence) during sterotactic EEG (SEEG).

Familial mesial temporal lobe epilepsy and the borderland of déjà vu.

Science.gov (United States)

Perucca, Piero; Crompton, Douglas E; Bellows, Susannah T; McIntosh, Anne M; Kalincik, Tomas; Newton, Mark R; Vajda, Frank J E; Scheffer, Ingrid E; Kwan, Patrick; O'Brien, Terence J; Tan, K Meng; Berkovic, Samuel F

2017-08-01

The cause of mesial temporal lobe epilepsy (MTLE) is often unknown. We ascertained to what extent newly diagnosed nonlesional MTLE actually represents familial MTLE (FMTLE). We identified all consecutive patients presenting to the Austin Health First Seizure Clinic with MTLE and normal magnetic resonance imaging (MRI) or MRI evidence of hippocampal sclerosis over a 10-year period. Patients' first-degree relatives and pairwise age- and sex-matched controls underwent a comprehensive epilepsy interview. Each interview transcript was reviewed independently by 2 epileptologists, blinded to relative or control status. Reviewers classified each subject as follows: epilepsy, specifying if MTLE; manifestations suspicious for epilepsy; or unaffected. Physiological déjà vu was noted. Forty-four patients were included. At the Clinic, MTLE had been recognized to be familial in 2 patients only. Among 242 subjects interviewed, MTLE was diagnosed in 9 of 121 relatives versus 0 of 121 controls (p = 0.008). All affected relatives had seizures with intense déjà vu and accompanying features; 6 relatives had not been previously diagnosed. Déjà vu experiences that were suspicious, but not diagnostic, of MTLE occurred in 6 additional relatives versus none of the controls (p = 0.04). Physiological déjà vu was common, and did not differ significantly between relatives and controls. After completing the relatives' interviews, FMTLE was diagnosed in 8 of 44 patients (18.2%). FMTLE accounts for almost one-fifth of newly diagnosed nonlesional MTLE, and it is largely unrecognized without direct questioning of relatives. Relatives of patients with MTLE may experience déjà vu phenomena that clinically lie in the "borderland" between epileptic seizures and physiological déjà vu. Ann Neurol 2017;82:166-176. © 2017 American Neurological Association.

Déjà vu experiences and reduplicative paramnesia

NARCIS (Netherlands)

Sno, H. N.; Linszen, D. H.; de Jonghe, F.

1992-01-01

A schizophrenic patient with different forms of experiences of inappropriate familiarity is described. The authors discuss traumatic experiences as aetiological factors in déjà vu experiences and reduplicative paramnesia. Finally, the differential diagnostic problem in psychotic and dissociative

The clinical and neurophysiological characteristics of the deja vu phenomenon in epilepsy

OpenAIRE

P. N. Vlasov; A. V. Chervyakov; G. R. Drozhzhina; М. V. Antonyuk; N. V. Orekhova; V. V. Gnezditsky; T. Yu. Noskova; P. A. Fedin

2012-01-01

Objective: to study the clinical and neurophysiological characteristics of the deja vu phenomenon in epilepsy. Patients and methods. The manifestations of the dВjЕ vu phenomenon were compared in 154 examinees in two groups: 1) 139 healthy individuals and 2) 25 patients with epilepsy (mean age 25.17±9.19 years; women, 63.2%) The characteristics of the phenomenon were determined, by questioning the examinees; 12—16-hour ambulatory electroencephalogram (EEG) monitoring was made. Results. The dej...

R7 VU Born-Assessed Demo Plan

Energy Technology Data Exchange (ETDEWEB)

Robert Nourgaliev

2010-02-01

This is an initial draft of a born-assessed VU plan for the RELAP7 (R7) code development effort. The plan will continue to evolve based on the growth of code capability. This growth will be reflected as additional testing is identified and done. Later versions of this document will reflect that growth.

A study on super-sulfated cement using Dinh Vu phosphogypsum

Science.gov (United States)

Lam, Nguyen Ngoc

2018-04-01

Super-sulfated cement (SSC) is a newly developed unburnt cementitious material. It is a kind of environmental-friendly cementitious material due to its energy-saving, carbon emission reducing, and waste-utilization. It mainly composes of phosphogysum (PG) and ground granulated blast furnace slag (GFS), with a small amount of cement. In Vietnam, the Diammonium Phosphate DAP – Dinh Vu fertilizer plant in Dinh Vu industrial zone in the northern port city of Hai Phong – has discharged millions of tons of solid waste containing gypsum after 9 years of operation. The waste has changed the color of the water, eroded metal and destroyed fauna and floral systems in the surrounding area. Notably, according to the environmental impact assessment, the gypsum landfill area is supposed to be 13 hectares and the storage time reaches up to five years. This paper presents the experimental results on SSC using a high amount of Dinh Vu phosphogypsum and GFS in comparison with those of ordinary Portland cement (PC). The results show that the setting time of SSC is much longer than that of Portland cement but the compressive strength of SSC can be obtained 45-50 MPa at the age of 28 days, similar to that of the control sample using 100% PC40, and 69MPa at the age of 90 days. This value even exceeds the compressive strength of the PC40 cement.

Déjà Vu Experiences in Healthy Czech Adults

Czech Academy of Sciences Publication Activity Database

Lacinová, L.; Neužilová Michalčáková, R.; Širůček, J.; Ježek, S.; Chromec, J.; Masopustová, Z.; Urbánek, Tomáš; Brázdil, M.

2016-01-01

Roč. 204, č. 12 (2016), s. 925-930 ISSN 0022-3018 Institutional support: RVO:68081740 Keywords : déjà vu * attachment * neuroticism * depression * irritability in the limbic system * perceived stress Subject RIV: AN - Psychology Impact factor: 1.860, year: 2016

VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy.

Science.gov (United States)

Nickols, Hilary Highfield; Yuh, Joannes P; Gregory, Karen J; Morrison, Ryan D; Bates, Brittney S; Stauffer, Shaun R; Emmitte, Kyle A; Bubser, Michael; Peng, Weimin; Nedelcovych, Michael T; Thompson, Analisa; Lv, Xiaohui; Xiang, Zixiu; Daniels, J Scott; Niswender, Colleen M; Lindsley, Craig W; Jones, Carrie K; Conn, P Jeffrey

2016-01-01

Negative allosteric modulators (NAMs) of metabotropic glutamate receptor subtype 5 (mGlu5) have potential applications in the treatment of fragile X syndrome, levodopa-induced dyskinesia in Parkinson disease, Alzheimer disease, addiction, and anxiety; however, clinical and preclinical studies raise concerns that complete blockade of mGlu5 and inverse agonist activity of current mGlu5 NAMs contribute to adverse effects that limit the therapeutic use of these compounds. We report the discovery and characterization of a novel mGlu5 NAM, N,N-diethyl-5-((3-fluorophenyl)ethynyl)picolinamide (VU0477573) that binds to the same allosteric site as the prototypical mGlu5 NAM MPEP but displays weak negative cooperativity. Because of this weak cooperativity, VU0477573 acts as a "partial NAM" so that full occupancy of the MPEP site does not completely inhibit maximal effects of mGlu5 agonists on intracellular calcium mobilization, inositol phosphate (IP) accumulation, or inhibition of synaptic transmission at the hippocampal Schaffer collateral-CA1 synapse. Unlike previous mGlu5 NAMs, VU0477573 displays no inverse agonist activity assessed using measures of effects on basal [(3)H]inositol phosphate (IP) accumulation. VU0477573 acts as a full NAM when measuring effects on mGlu5-mediated extracellular signal-related kinases 1/2 phosphorylation, which may indicate functional bias. VU0477573 exhibits an excellent pharmacokinetic profile and good brain penetration in rodents and provides dose-dependent full mGlu5 occupancy in the central nervous system (CNS) with systemic administration. Interestingly, VU0477573 shows robust efficacy, comparable to the mGlu5 NAM MTEP, in models of anxiolytic activity at doses that provide full CNS occupancy of mGlu5 and demonstrate an excellent CNS occupancy-efficacy relationship. VU0477573 provides an exciting new tool to investigate the efficacy of partial NAMs in animal models. Copyright © 2015 by The American Society for Pharmacology and

Characterization of VuMATE1 expression in response to iron nutrition and aluminum stress reveals adaptation of rice bean (Vigna umbellata to acid soils through cis regulation

Directory of Open Access Journals (Sweden)

Meiya eLiu

2016-04-01

Full Text Available Rice bean (Vigna umbellata VuMATE1 appears to be constitutively expressed at vascular system but root apex, and Al stress extends its expression to root apex. Whether VuMATE1 participates in both Al tolerance and Fe nutrition, and how VuMATE1 expression is regulated is of great interest. In this study, the role of VuMATE1 in Fe nutrition was characterized through in planta complementation assays. The transcriptional regulation of VuMATE1 was investigated through promoter analysis and promoter-GUS reporter assays. The results showed that the expression of VuMATE1 was regulated by Al stress but not Fe status. Complementation of frd3-1 with VuMATE1 under VuMATE1 promoter could not restore phenotype, but restored with 35SCaMV promoter. Immunostaining of VuMATE1 revealed abnormal localization of VuMATE1 in vasculature. In planta GUS reporter assay identified Al-responsive cis-acting elements resided between -1228 and -574 bp. Promoter analysis revealed several cis-acting elements, but transcription is not simply regulated by one of these elements. We demonstrated that cis regulation of VuMATE1 expression is involved in Al tolerance mechanism, while not involved in Fe nutrition. These results reveal the evolution of VuMATE1 expression for better adaptation of rice bean to acidic soils where Al stress imposed but Fe deficiency pressure released.

Déjà vu experiences in healthy subjects are unrelated to laboratory tests of recollection and familiarity for word stimuli

Directory of Open Access Journals (Sweden)

Akira Robert O'Connor

2013-11-01

Full Text Available Recent neuropsychological and neuroscientific research suggests that people who experience more déjà vu display characteristic patterns in normal recognition memory. We conducted a large individual differences study (n = 206 to test these predictions using recollection and familiarity parameters recovered from a standard memory task. Participants reported déjà vu frequency and a number of its correlates, and completed a recognition memory task analogous to a Remember-Know procedure. The individual difference measures replicated an established correlation between déjà vu frequency and frequency of travel, and recognition performance showed well-established word frequency and accuracy effects. Contrary to predictions, no relationships were found between déjà vu frequency and recollection or familiarity memory parameters from the recognition test. We suggest that déjà vu in the healthy population reflects a mismatch between errant memory signalling and memory monitoring processes not easily characterised by standard recognition memory task performance.

The Persistence of Erroneous Familiarity in an Epileptic Male: Challenging Perceptual Theories of Deja Vu Activation

Science.gov (United States)

O'Connor, Akira R.; Moulin, Christopher J. A.

2008-01-01

We report the case of a 39-year-old, temporal lobe epileptic male, MH. Prior to complex partial seizure, experienced up to three times a day, MH often experiences an aura experienced as a persistent sensation of deja vu. Data-driven theories of deja vu formation suggest that partial familiarity for the perceived stimulus is responsible for the…

The persistence of erroneous familiarity in an epileptic male : Challenging perceptual theories of déjà vu activation

OpenAIRE

O'Connor, Akira Robert; Moulin, Christopher J. A.

2008-01-01

We report the case of a 39-year-old, temporal lobe epileptic male, MH. Prior to complex partial seizure, experienced up to three times a day, MH often experiences an aura experienced as a persistent sensation of deja vu. Data-driven theories of deja vu formation suggest that partial familiarity for the perceived stimulus is responsible for the sensation. Consequently, diverting attention away from this stimulus should cause the sensation to dissipate. MH, whose sensations of deja vu persist l...

Obama vu de ma banlieue.

Directory of Open Access Journals (Sweden)

Olga Stanislawska

2008-12-01

Full Text Available Une petite brocante est organisée tous les jeudis sur une place proche de la Basilique de Saint-Denis. On y vend des livres, des bibelots, des bijoux fantaisies et des masques africains. L’un des vendeurs a visiblement décidé de bénéficier de l’effet Obama. J’ai pris la photo de ma fenêtre, située au dessus de ce marché. J’ai adoré ce stand, mais ce n’est qu’une fois sur l’écran de mon ordinateur que j’ai vu les petites images Banania... ! Si j’avais su, je serais ...

Transformation Deja Vu? A Comparison of Military Improvements of Israel (1967-1973) and the United States (1990-2002)

Science.gov (United States)

2002-09-06

Transformation Déjà Vu ? A Comparison of Military Improvements of Israel (1967-1973) and the United States (1990-2002) Major William A. Forkner, USAF...Transformation Déjà Vu ? A Comparison of Military Improvements of Israel (1967-1973) and the United States (1990-2002) 5a. CONTRACT NUMBER 5b. GRANT NUMBER

Spine biomechanics associated with the shortened, modern one-plane golf swing.

Science.gov (United States)

Dale, R Barry; Brumitt, Jason

2016-06-01

The purpose of this study was to compare kinetic, kinematic, and performance variables associated with full and shortened modern backswings in a skilled group of modern swing (one-plane) golfers. Shortening the modern golf backswing is proposed to reduce vertebral spine stress, but supporting evidence is lacking and performance implications are unknown. Thirteen male golfers performed ten swings of each swing type using their own 7-iron club. Biomechanical-dependent variables included the X-Factor kinematic data and spine kinetics. Performance-related dependent variables included club head velocity (CHV), shot distance, and accuracy (distance from the target line). Data were analysed with repeated measures ANOVA with an a priori alpha of 0.05 (SPSS 22.0, IBM, Armonk, NY, USA). We found significant reductions for the X-Factor (p < 0.05) between the full and shortened swings. The shortened swing condition ameliorated vertebral compression force from 7.6 ± 1.4 to 7.0 ± 1.7 N (normalised to body weight, p = 0.01) and significantly reduced CHV (p < 0.05) by ~2 m/s with concomitant shot distance diminution by ~10 m (p < 0.05). Further research is necessary to examine the applicability of a shortened swing for golfers with low back pain.

Deja Vu in Unilateral Temporal-Lobe Epilepsy Is Associated with Selective Familiarity Impairments on Experimental Tasks of Recognition Memory

Science.gov (United States)

Martin, Chris B.; Mirsattari, Seyed M.; Pruessner, Jens C.; Pietrantonio, Sandra; Burneo, Jorge G.; Hayman-Abello, Brent; Kohler, Stefan

2012-01-01

In deja vu, a phenomenological impression of familiarity for the current visual environment is experienced with a sense that it should in fact not feel familiar. The fleeting nature of this phenomenon in daily life, and the difficulty in developing experimental paradigms to elicit it, has hindered progress in understanding deja vu. Some…

Déjà Vu: tradução assistida ao pormenor.

Directory of Open Access Journals (Sweden)

Leonel Morgado

2004-01-01

Full Text Available No campo da tradução assistida por computador, apresenta-se aqui o programa Déjà Vu. Entre outras características interessantes, este programa possui uma funcionalidade fundamental e pioneira, que contribui significativamente para a melhoria do desempenho, da coerência e da rapidez do trabalho de tradução: o reaproveitamento automático de partes de expressões, não apenas de expressões inteiras. O tradutor pode, rapidamente, enviar para a memória de tradução pares linguísticos tão simples como uma simples palavra e a respectiva tradução, não apenas frases inteiras. À medida que o programa Déjà Vu recebe os pares, passa a utilizá-los para traduzir pedaços das frases e expressões que vão surgindo, não apenas frases inteiras (se o tradutor preferir, o Déjà Vu pode apenas sugerir as traduções, em vez de as aplicar. Desta forma, o tradutor é apoiado automaticamente, mas não apenas na terminologia e nos casos de repetição de frases, como é mais habitual. Pode passar a ter apoio relativamente às formas que utiliza para expressões ou combinações de palavras que se revelem frequentes num projecto específico, ainda que não sejam suficientemente relevante para integrar glossários ou outras bases de dados terminológicas.

The déjà vu experience: remembrance of things past?

NARCIS (Netherlands)

Sno, H. N.; Linszen, D. H.

1990-01-01

The déjà vu experience is a common phenomenon, occurring in pathological as well as nonpathological conditions. It has been defined as any subjectively inappropriate impression of familiarity of a present experience with an undefined past. The authors discuss the epidemiologic data, clinical

Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590.

Science.gov (United States)

Kharade, Sujay V; Sheehan, Jonathan H; Figueroa, Eric E; Meiler, Jens; Denton, Jerod S

2017-09-01

VU590 was the first publicly disclosed, submicromolar-affinity (IC 50 = 0.2 μ M), small-molecule inhibitor of the inward rectifier potassium (Kir) channel and diuretic target, Kir1.1. VU590 also inhibits Kir7.1 (IC 50 ∼ 8 μ M), and has been used to reveal new roles for Kir7.1 in regulation of myometrial contractility and melanocortin signaling. Here, we employed molecular modeling, mutagenesis, and patch clamp electrophysiology to elucidate the molecular mechanisms underlying VU590 inhibition of Kir1.1 and Kir7.1. Block of both channels is voltage- and K + -dependent, suggesting the VU590 binding site is located within the pore. Mutagenesis analysis in Kir1.1 revealed that asparagine 171 (N171) is the only pore-lining residue required for high-affinity block, and that substituting negatively charged residues (N171D, N171E) at this position dramatically weakens block. In contrast, substituting a negatively charged residue at the equivalent position in Kir7.1 enhances block by VU590, suggesting the VU590 binding mode is different. Interestingly, mutations of threonine 153 (T153) in Kir7.1 that reduce constrained polarity at this site (T153C, T153V, T153S) make wild-type and binding-site mutants (E149Q, A150S) more sensitive to block by VU590. The Kir7.1-T153C mutation enhances block by the structurally unrelated inhibitor VU714 but not by a higher-affinity analog ML418, suggesting that the polar side chain of T153 creates a barrier to low-affinity ligands that interact with E149 and A150. Reverse mutations in Kir1.1 suggest that this mechanism is conserved in other Kir channels. This study reveals a previously unappreciated role of membrane pore polarity in determination of Kir channel inhibitor pharmacology. Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics.

Comparison of Ear-Canal Reflectance and Umbo Velocity in Patients with Conductive Hearing Loss

Science.gov (United States)

Merchant, Gabrielle R.; Nakajima, Hideko H.; Pisano, Dominic V.; Röösli, Christof; Hamade, Mohamad A.; Mafoud, Lorice; Halpin, Christopher F.; Merchant, Saumil N.; Rosowski, John J.

2011-11-01

Patients who present at hearing clinics with a conductive hearing loss (CHL) in the presence of an intact, healthy tympanic membrane create a unique challenge for otologists. While patient counseling, treatment options, and outcome vary with differing middle-ear pathologies, a non-invasive diagnostic that can differentiate between these pathologies does not currently exist. We evaluated the clinical utility and diagnostic accuracy of two non-invasive measures of middle-ear mechanics: ear-canal reflectance (ECR) and umbo velocity (VU).

The curve shortening problem

CERN Document Server

Chou, Kai-Seng

2001-01-01

Although research in curve shortening flow has been very active for nearly 20 years, the results of those efforts have remained scattered throughout the literature. For the first time, The Curve Shortening Problem collects and illuminates those results in a comprehensive, rigorous, and self-contained account of the fundamental results.The authors present a complete treatment of the Gage-Hamilton theorem, a clear, detailed exposition of Grayson''s convexity theorem, a systematic discussion of invariant solutions, applications to the existence of simple closed geodesics on a surface, and a new, almost convexity theorem for the generalized curve shortening problem.Many questions regarding curve shortening remain outstanding. With its careful exposition and complete guide to the literature, The Curve Shortening Problem provides not only an outstanding starting point for graduate students and new investigations, but a superb reference that presents intriguing new results for those already active in the field.

Art imitates life: Déjà vu experiences in prose and poetry

NARCIS (Netherlands)

Sno, H. N.; Linszen, D. H.; de Jonghe, F.

1992-01-01

the déjà vu experience is a subjective phenomenon that has been described in many novels and poems. Here we review over 20 literary descriptions. These accounts are consistent with the data obtained from psychiatric literature, including various phenomenological, aetiological and psychopathogenetic

Influence of sex on performance fatigability of the plantar flexors following repeated maximal dynamic shortening contractions.

Science.gov (United States)

Lanning, Amelia C; Power, Geoffrey A; Christie, Anita D; Dalton, Brian H

2017-10-01

The purpose was to determine sex differences in fatigability during maximal, unconstrained velocity, shortening plantar flexions. The role of time-dependent measures (i.e., rate of torque development, rate of velocity development, and rate of neuromuscular activation) in such sex-related differences was also examined. By task termination, females exhibited smaller reductions in power and similar changes in rate of neuromuscular activation than males, indicating females were less fatigable than males.

EEG characteristics of déjà vu phenomenon

OpenAIRE

Chervyakov, Alexander V.; Gnezditskii, Victor V.; Vlasov, Pavel N.; Kalmykova, Galina V.

2013-01-01

Introduction. Déjà vu (DV, from French “already seen”) is an aberration of psychic activity associated with transitory erroneous perception of novel circumstances, objects, or people as already known. Aim. Investigation of clinical and diagnostic significance of derealization episodes in epilepsy. Materials and methods. The study involved 166 individuals (mean age 25.2 ± 9.2 yrs; 63.2% women). DV episodes were characterized and compared in groups of healthy volunteers (n = 139) and epilepsy...

Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia.

Science.gov (United States)

Wood, Michael R; Noetzel, Meredith J; Melancon, Bruce J; Poslusney, Michael S; Nance, Kellie D; Hurtado, Miguel A; Luscombe, Vincent B; Weiner, Rebecca L; Rodriguez, Alice L; Lamsal, Atin; Chang, Sichen; Bubser, Michael; Blobaum, Anna L; Engers, Darren W; Niswender, Colleen M; Jones, Carrie K; Brandon, Nicholas J; Wood, Michael W; Duggan, Mark E; Conn, P Jeffrey; Bridges, Thomas M; Lindsley, Craig W

2017-02-09

Herein, we report the structure-activity relationships within a series of potent, selective, and orally bioavailable muscarinic acetylcholine receptor 4 (M 4 ) positive allosteric modulators (PAMs). Compound 6c (VU0467485) possesses robust in vitro M 4 PAM potency across species and in vivo efficacy in preclinical models of schizophrenia. Coupled with an attractive DMPK profile and suitable predicted human PK, 6c (VU0467485) was evaluated as a preclinical development candidate.

Shortening Scarf osteotomy for correction of severe hallux valgus. Does shortening affect the outcome?

Science.gov (United States)

Karpe, Prasad; Killen, Marie C; Pollock, Raymond D; Limaye, Rajiv

2016-12-01

Translation and shortening of Scarf osteotomy allows correction of severe hallux valgus deformity. Shortening may result in transfer metatarsalgia. To evaluate outcome of patients undergoing shortening Scarf osteotomy for severe hallux valgus deformities. Fifteen patients (20feet, mean age 58 years) underwent shortening Scarf osteotomy for severe hallux valgus deformities. Outcomes were pre and postoperative AOFAS scores, IM and HV angles, patient satisfaction. Mean follow-up was 25 months (range 22-30). The IM angle improved from a median of 18.60 (range 13.4-26.20) preoperatively to 9.70 (range 8.0-13.70) postoperatively (8.9; 95% CI=7.6-10.3; phallux valgus deformities with no transfer metatarsalgia. Copyright © 2016 Elsevier Ltd. All rights reserved.

[Electroencephalographic characteristics of the deja vu phenomenon].

Science.gov (United States)

Vlasov, P N; Cherviakov, A V; Gnezdinsiĭ, V V

2013-01-01

Déjà vu (DV, from French "already seen") is an aberration of psychic activity associated with transitory erroneous perception of novel circumstances, objects, or people as already known. An aim of the study was to investigate EEG characteristics of DV in patients with epilepsy. We studied 166 people (63.2% women, mean age 25.17±9.19 years). The DV phenomenon was studied in patients (27 people) and in a control group (139 healthy people). Patients were interviewed for DV characteristics and underwent a long (12-16 h) ambulatory EEG-monitoring study. In EEG, DV episodes in patients began with polyspike activity in the right temporal lobe and, in some cases, ended with the slow-wave theta-delta activity in the right hemisphere.

Effects of rapid shortening on rate of force regeneration and myoplasmic [Ca2+] in intact frog skeletal muscle fibres

Science.gov (United States)

Vandenboom, R; Claflin, D R; Julian, F J

1998-01-01

The effect of rapid shortening on rate of force regeneration (dF/dtR) was examined in single, intact frog (Rana temporaria) skeletal muscle fibres (3·0 °C). Step releases leading to unloaded shortening were applied after 500 ms of stimulation, during the plateau of an isometric tetanus. Initial mean sarcomere length ranged from 2·05 to 2·35 μm; force regeneration after shortening was at 2·00 μm.Values for dF/dtR following a 25 nm half-sarcomere−1 release were 3·17 ± 0·17 (mean ± s.e.m., n= 8) times greater than the initial rate of rise of force before release (dF/dtI). As release size was increased from 25 to 175 nm half-sarcomere−1, the relationship between release size and dF/dtR decreased sharply before attaining a plateau value that was 1·34 ± 0·09 times greater than dF/dtI. Despite wide variations in dF/dtR, the velocity of unloaded shortening remained constant (2·92 ± 0·08 μm half-sarcomere−1 s−1; n= 8) for the different release amplitudes used in this study.To investigate its role in the attenuation of dF/dtR with increased shortening, the effects of rapid ramp (constant velocity) shortening on intracellular free Ca2+ concentration ([Ca2+]i) were monitored using the Ca2+-sensitive fluorescent dye furaptra. Compared with an isometric contraction, rapid fibre shortening was associated with a transient increase in [Ca2+]i while force regeneration after shortening was associated with a transient reduction in [Ca2+]i. The greatest reductions in [Ca2+]i were associated with the largest amplitude ramps.Cross-bridge-mediated modifications of the Ca2+ affinity of troponin C (TnC) may explain the fluctuations in [Ca2+]i observed during and after ramps. Associated fluctuations in TnC Ca2+ occupancy could play a role in the reduction of dF/dtR with increasing release size. PMID:9679172

Complex myograph allows the examination of complex muscle contractions for the assessment of muscle force, shortening, velocity, and work in vivo

Directory of Open Access Journals (Sweden)

Ruhschulte Hainer

2008-07-01

Full Text Available Abstract Background The devices used for in vivo examination of muscle contractions assess only pure force contractions and the so-called isokinetic contractions. In isokinetic experiments, the extremity and its muscle are artificially moved with constant velocity by the measuring device, while a tetanic contraction is induced in the muscle, either by electrical stimulation or by maximal voluntary activation. With these systems, experiments cannot be performed at pre-defined, constant muscle length, single contractions cannot be evaluated individually and the separate examination of the isometric and the isotonic components of single contractions is not possible. Methods The myograph presented in our study has two newly developed technical units, i.e. a. a counterforce unit which can load the muscle with an adjustable, but constant force and b. a length-adjusting unit which allows for both the stretching and the contraction length to be infinitely adjustable independently of one another. The two units support the examination of complex types of contraction and store the counterforce and length-adjusting settings, so that these conditions may be accurately reapplied in later sessions. Results The measurement examples presented show that the muscle can be brought to every possible pre-stretching length and that single isotonic or complex isometric-isotonic contractions may be performed at every length. The applied forces act during different phases of contraction, resulting into different pre- and after-loads that can be kept constant – uninfluenced by the contraction. Maximal values for force, shortening, velocity and work may be obtained for individual muscles. This offers the possibility to obtain information on the muscle status and to monitor its changes under non-invasive measurement conditions. Conclusion With the Complex Myograph, the whole spectrum of a muscle's mechanical characteristics may be assessed.

Schizophrenia and the paranormal: more psi belief and superstition, and less déjà vu in medicated schizophrenic patients.

Science.gov (United States)

Shiah, Yung-Jong; Wu, Yi-Zhen; Chen, Yueh-Hua; Chiang, Shih-Kuang

2014-04-01

The present study examined the relation between déjà vu experiences and paranormal beliefs in schizophrenic patients. A total of 522 participants (54.5% female; mean age=33.3, SD=16.02) were recruited, including 422 healthy adults (60.9% female; mean age=29.48, SD=15.07) and 100 medicated adult schizophrenic patients (27.3% female; mean age=48.98, SD=8.57). The Chinese version of the Inventory of Déjà-vu Experiences Assessment was created via back translation. Chinese versions of the Revised Paranormal Belief Scale (CRPB), Beck Anxiety Inventory (CBAI), and Perceived Stress Scale (CPSS) were also used. After controlling for age, gender, education, and anxiety, the results supported the following three hypotheses. Schizophrenic persons have fewer déjà vu experiences than normal persons. These experiences are positively related to paranormal beliefs in healthy adults but not in schizophrenic patients. Schizophrenic patients have higher scores than healthy adults on the psi and superstitious subscales of the CRPB. Copyright © 2014 Elsevier Inc. All rights reserved.

Does oxidative stress shorten telomeres?

NARCIS (Netherlands)

Boonekamp, Jelle J.; Bauch, Christina; Mulder, Ellis; Verhulst, Simon

Oxidative stress shortens telomeres in cell culture, but whether oxidative stress explains variation in telomere shortening in vivo at physiological oxidative stress levels is not well known. We therefore tested for correlations between six oxidative stress markers and telomere attrition in nestling

Draft genome sequence of Bacillus toyonensis VU-DES13, isolated from Folsomia candida (Collembola: Entomobryidae)

NARCIS (Netherlands)

Janssens, T.K.S.; de Boer, T.E.; Agamennone, V.; Zaagman, N.; van Straalen, N.M.; Roelofs, T.F.M.

2017-01-01

We present here the draft genome of Bacillus toyonensis VU-DES13, which was isolated from the midgut of the soil-living springtail Folsomia candida. Previous research revealed the presence of gene clusters for the biosynthesis of various secondary metabolites, including -lactam antibiotics, in the

Occlusal stability in shortened dental arches.

Science.gov (United States)

Witter, D J; Creugers, N H; Kreulen, C M; de Haan, A F

2001-02-01

Shortened dental arches consisting of anterior and premolar teeth have been shown to meet oral functional demands. However, the occlusal stability may be at risk as a result of tooth migration. The aim of this nine-year study was to investigate occlusal stability in shortened dental arches as a function over time. Occlusal stability indicators were: 'interdental spacing', 'occlusal contacts of anterior teeth in Intercuspal Position', 'overbite', 'occlusal tooth wear', and 'alveolar bone support'. Subjects with shortened dental arches (n = 74) were compared with subjects with complete dental arches (controls, n = 72). Repeated-measurement regression analyses were applied to assess age-dependent variables in the controls and to relate the occlusal changes to the period of time since the treatment that led to the shortened dental arches. Compared with complete dental arches, shortened dental arches had similar overbite and occlusal tooth wear. They showed more interdental spacing in the premolar regions, more anterior teeth in occlusal contact, and lower alveolar bone scores. Since the differences remained constant over time, we conclude that shortened dental arches can provide long-term occlusal stability. Occlusal changes were self-limiting, indicating a new occlusal equilibrium.

Further optimization of the M1 PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetration.

Science.gov (United States)

Panarese, Joseph D; Cho, Hykeyung P; Adams, Jeffrey J; Nance, Kellie D; Garcia-Barrantes, Pedro M; Chang, Sichen; Morrison, Ryan D; Blobaum, Anna L; Niswender, Colleen M; Stauffer, Shaun R; Conn, P Jeffrey; Lindsley, Craig W

2016-08-01

This Letter describes the continued chemical optimization of the VU0453595 series of M1 positive allosteric modulators (PAMs). By surveying alternative 5,6- and 6,6-heterobicylic cores for the 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-5-one core of VU453595, we found new cores that engendered not only comparable or improved M1 PAM potency, but significantly improved CNS distribution (Kps 0.3-3.1). Moreover, this campaign provided fundamentally distinct M1 PAM chemotypes, greatly expanding the available structural diversity for this valuable CNS target, devoid of hydrogen-bond donors. Copyright © 2016 Elsevier Ltd. All rights reserved.

T2 shortening in childhood moyamoya disease

International Nuclear Information System (INIS)

Takanashi, J.; Sugita, K.; Tanabe, Y.; Ito, C.; Date, H.; Niimi, H.

1996-01-01

We examined T2 shortening in six children with infarcts due to moyamoya disease to clarify whether there are characteristic patterns of T2 shortening in the deep grey and white matter. Profound T2 shortening in the deep grey and white matter was observed in the acute stage of infarct in two cases, which changed to high intensity in the chronic stage; in this stage no T2 shortening was demonstrated in any case. Neither haemorrhagic infarction nor calcification was seen on CT or MRI. There could be longitudinally different T2 shortening patterns between infarcts due to moyamoya disease and other disorders. (orig.). With 2 figs., 1 tab

The inventory for déjà vu experiences assessment. Development, utility, reliability, and validity

NARCIS (Netherlands)

Sno, H. N.; Schalken, H. F.; de Jonghe, F.; Koeter, M. W.

1994-01-01

In this article the development, utility, reliability, and validity of the Inventory for Déjà vu Experiences Assessment (IDEA) are described. The IDEA is a 23-item self-administered questionnaire consisting of a general section of nine questions and qualitative section of 14 questions. The latter

9 CFR 319.701 - Mixed fat shortening.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Mixed fat shortening. 319.701 Section... § 319.701 Mixed fat shortening. Shortening prepared with a mixture of meat fats and vegetable oils may... descending order of predominance. ...

Comparison of ear-canal reflectance and umbo velocity in patients with conductive hearing loss: a preliminary study.

Science.gov (United States)

Nakajima, Hideko H; Pisano, Dominic V; Roosli, Christof; Hamade, Mohamad A; Merchant, Gabrielle R; Mahfoud, Lorice; Halpin, Christopher F; Rosowski, John J; Merchant, Saumil N

2012-01-01

The goal of the present study was to investigate the clinical utility of measurements of ear-canal reflectance (ECR) in a population of patients with conductive hearing loss in the presence of an intact, healthy tympanic membrane and an aerated middle ear. We also sought to compare the diagnostic accuracy of umbo velocity (VU) measurements and measurements of ECR in the same group of patients. This prospective study comprised 31 adult patients with conductive hearing loss, of which 14 had surgically confirmed stapes fixation due to otosclerosis, 6 had surgically confirmed ossicular discontinuity, and 11 had computed tomography and vestibular evoked myogenic potential confirmed superior semicircular canal dehiscence (SCD). Measurements on all 31 ears included pure-tone audiometry for 0.25 to 8 kHz, ECR for 0.2 to 6 kHz using the Mimosa Acoustics HearID system, and VU for 0.3 to 6 kHz using the HLV-1000 laser Doppler vibrometer (Polytec Inc, Waldbronn, Germany). We analyzed power reflectance |ECR| as well as the absorbance level = 10 × log10(1 - |ECR|). All measurements were made before any surgical intervention. The VU and ECR data were plotted against normative data obtained in a companion study of 58 strictly defined normal ears (). Small increases in |ECR| at low-to-mid frequencies (400-1000 Hz) were observed in cases with stapes fixation, while narrowband decreases were seen for both SCD and ossicular discontinuity. The SCD and ossicular discontinuity differed in that the SCD had smaller decreases at mid-frequency (∼1000 Hz), whereas ossicular discontinuity had larger decreases at lower frequencies (500-800 Hz). SCD tended to have less air-bone gap at high frequencies (1-4 kHz) compared with stapes fixation and ossicular discontinuity. The |ECR| measurements, in conjunction with audiometry, could successfully separate 28 of the 31 cases into the three pathologies. By comparison, VU measurements, in conjunction with audiometry, could successfully separate

A novel M1 PAM VU0486846 exerts efficacy in cognition models without displaying agonist activity or cholinergic toxicity.

Science.gov (United States)

Rook, Jerri M; Bertron, Jeanette L; Cho, Hyekyung P; Garcia-Barrantes, Pedro M; Moran, Sean P; Maksymetz, James T; Nance, Kellie D; Dickerson, Jonathan W; Remke, Daniel H; Chang, Sichen; Harp, Joel; Blobaum, Anna L; Niswender, Colleen M; Jones, Carrie K; Stauffer, Shaun R; Conn, P Jeffrey; Lindsley, Craig W

2018-04-27

Selective activation of the M1 subtype of muscarinic acetylcholine receptor, via positive allosteric modulation (PAM), is an exciting strategy to improve cognition in schizophrenia and Alzheimer's disease patients. However, highly potent M1 ago-PAMs, such as MK-7622, PF-06764427, and PF-06827443, can engender excessive activation of M1, leading to agonist actions in the prefrontal cortex (PFC) that impairs cognitive function, induces behavioral convulsions, and results in other classic cholinergic adverse events (AEs). Here, we report a fundamentally new and highly selective M1 PAM, VU0486846. VU0486846 possesses only weak agonist activity in M1-expressing cell lines with high receptor reserve and is devoid of agonist actions in the PFC, unlike previously reported ago-PAMs MK-7622, PF-06764427 and PF-06827443. Moreover, VU0486846 shows no interaction with antagonist binding at the orthosteric acetylcholine (ACh) site (e.g., neither bitopic nor displaying negative cooperativity with [3H]-NMS binding at theorthosteric site), no seizure liability at high brain exposures, and no cholinergic AEs. However, as opposed to ago-PAMs, VU0486846 produces robust efficacy in the novel object recognition model of cognitive function. Importantly, we show for the first time that an M1 PAM can reverse the cognitive deficits induced by atypical antipsychotics, such as risperidone. These findings further strengthen the argument that compounds with modest in vitro M1 PAM activity (EC50s > 100 nM) and pure-PAM activity in native tissues display robust pro-cognitive efficacy without AEs mediated by excessive activation of M1. Overall, the combination of compound assessment with recombinant in vitro assays (mindful of receptor reserve), native tissue systems (PFC), and phenotypic screens (behavioral convulsions) is essential to fully understand and evaluate lead compounds and enhance success in clinical development.

Measurement of nucleotide exchange rate constants in single rabbit soleus myofibrils during shortening and lengthening using a fluorescent ATP analog.

Science.gov (United States)

Shirakawa, I; Chaen, S; Bagshaw, C R; Sugi, H

2000-02-01

The kinetics of displacement of a fluorescent nucleotide, 2'(3')-O-[N[2-[[Cy3]amido]ethyl]carbamoyl]-adenosine 5'-triphosphate (Cy3-EDA-ATP), bound to rabbit soleus muscle myofibrils were studied using flash photolysis of caged ATP. Use of myofibrils from this slow twitch muscle allowed better resolution of the kinetics of nucleotide exchange than previous studies with psoas muscle myofibrils (, Biophys. J. 73:2033-2042). Soleus myofibrils in the presence of Cy3-EDA-nucleotides (Cy3-EDA-ATP or Cy3-EDA-ADP) showed selective fluorescence staining of the A-band. The K(m) for Cy3-EDA-ATP and the K(d) for Cy3-EDA-ADP binding to the myofibril A-band were 1.9 microM and 3.8 microM, respectively, indicating stronger binding of nucleotide to soleus cross-bridges compared to psoas cross-bridges (2.6 microM and 50 microM, respectively). After flash photolysis of caged ATP, the A-band fluorescence of the myofibril in the Cy3-EDA-ATP solution under isometric conditions decayed exponentially with a rate constant of 0.045 +/- 0.007 s(-1) (n = 32) at 10 degrees C, which was about seven times slower than that for psoas myofibrils. When a myofibril was allowed to shorten with a constant velocity, the nucleotide displacement rate constant increased from 0.066 s(-1) (isometric) to 0.14 s(-1) at 20 degrees C with increasing shortening velocity up to 0.1 myofibril length/s (V(max), the shortening velocity under no load was approximately 0. 2 myofibril lengths/s). The rate constant was not significantly affected by an isovelocity stretch of up to 0.1 myofibril lengths/s. These results suggest that the cross-bridge kinetics are not significantly affected at higher strain during lengthening but depend on the lower strain during shortening. These data also indicate that the interaction distance between a cross-bridge and the actin filament is at least 16 nm for a single cycle of the ATPase.

Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M4 PAM VU0467154.

Science.gov (United States)

Gould, Robert W; Grannan, Michael D; Gunter, Barak W; Ball, Jacob; Bubser, Michael; Bridges, Thomas M; Wess, Jurgen; Wood, Michael W; Brandon, Nicholas J; Duggan, Mark E; Niswender, Colleen M; Lindsley, Craig W; Conn, P Jeffrey; Jones, Carrie K

2018-01-01

Although selective activation of the M 1 muscarinic acetylcholine receptor (mAChR) subtype has been shown to improve cognitive function in animal models of neuropsychiatric disorders, recent evidence suggests that enhancing M 4 mAChR function can also improve memory performance. Positive allosteric modulators (PAMs) targeting the M 4 mAChR subtype have shown therapeutic potential for the treatment of multiple symptoms observed in schizophrenia, including positive and cognitive symptoms when assessed in acute preclinical dosing paradigms. Since the cholinergic system has been implicated in multiple stages of learning and memory, we evaluated the effects of repeated dosing with the highly selective M 4 PAM VU0467154 on either acquisition and/or consolidation of learning and memory when dosed alone or after pharmacologic challenge with the N-methyl-d-aspartate subtype of glutamate receptors (NMDAR) antagonist MK-801. MK-801 challenge represents a well-documented preclinical model of NMDAR hypofunction that is thought to underlie some of the positive and cognitive symptoms observed in schizophrenia. In wildtype mice, 10-day, once-daily dosing of VU0467154 either prior to, or immediately after daily testing enhanced the rate of learning in a touchscreen visual pairwise discrimination task; these effects were absent in M 4 mAChR knockout mice. Following a similar 10-day, once-daily dosing regimen of VU0467154, we also observed 1) improved acquisition of memory in a cue-mediated conditioned freezing paradigm, 2) attenuation of MK-801-induced disruptions in the acquisition of memory in a context-mediated conditioned freezing paradigm and 3) reversal of MK-801-induced hyperlocomotion. Comparable efficacy and plasma and brain concentrations of VU0467154 were observed after repeated dosing as those previously reported with an acute, single dose administration of this M 4 PAM. Together, these studies are the first to demonstrate that cognitive enhancing and antipsychotic

Transport properties of Dirac electrons in graphene based double velocity-barrier structures in electric and magnetic fields

International Nuclear Information System (INIS)

Liu, Lei; Li, Yu-Xian; Liu, Jian-Jun

2012-01-01

Using transfer matrix method, transport properties in graphene based double velocity-barrier structures under magnetic and electric fields are numerically studied. It is found that velocity barriers for the velocity ratio (the Fermi velocity inside the barrier to that outside the barrier) less than one (or for the velocity ratio greater than one) have properties similar to electrostatic wells (or barriers). The velocity barriers for the velocity ratio greater than one significantly enlarge the resonant tunneling region of electrostatic barriers. In the presence of magnetic field, the plateau width of the Fano factor with a Poissonian value shortens (or broadens) for the case of the velocity ratio less than one (or greater than one). When the Fermi energy is equal to the electrostatic barrier height, for different values of the velocity ratio, both the conductivities and the Fano factors remain fixed. -- Highlights: ► We model graphene based velocity-barrier structures in electric and magnetic fields. ► Velocity barrier for ξ 1) have property similar to electrostatic well (barrier). ► Velocity barrier for ξ>1 enlarge the resonant tunneling region of electrostatic barrier. ► The plateau width of Fano factor shortens (or broadens) for the case of ξ 1). ► The conductivity remains fixed at the point of E F =U 0 for different values of ξ.

Occlusal stability in shortened dental arches.

NARCIS (Netherlands)

Witter, D.J.; Creugers, N.H.J.; Kreulen, C.M.; Haan, A. de

2001-01-01

Shortened dental arches consisting of anterior and premolar teeth have been shown to meet oral functional demands. However, the occlusal stability may be at risk as a result of tooth migration. The aim of this nine-year study was to investigate occlusal stability in shortened dental arches as a

Hydrological and Agricultural Impacts of Climate Change in the Vu Gia-Thu Bon River Basin in Central Vietnam

NARCIS (Netherlands)

Laux, Patrick; Fink, Manfred; Waongo, Moussa; Pedroso, Rui; Salvini, G.; Hoa Tran, Dang; Quang Thinh, Dang; Cullmann, Johannes; Flügel, Wolfgang-Alvert; Kunstmann, H.

2017-01-01

This paper summarizes some of the climate (change) impact modeling activities conducted in the Land useandClimate Changeinteractionsin Central Vietnam (LUCCi)project. The study area is the Vu Gia-Thu Bon (VGTB) river basin in Central Vietnam, which is characterized by recurrent floods during

Radiation-induced life shortening. Annex K

International Nuclear Information System (INIS)

1982-01-01

The purpose of this Annex is to review the cumulative evidence in the field of non-neoplastic long-term effects of whole-body irradiation. In particular, the existence and extent of life-span shortening in irradiated animals and man, and the relationships of life shortening to the physical and biological variables which may influence this effect of radiation are examined.

Pathologies of Hyperfamiliarity in Dreams, Delusions and Déjà Vu

Directory of Open Access Journals (Sweden)

Philip eGerrans

2014-02-01

Full Text Available The ability to challenge and revise thoughts prompted by anomalous experiences depends on activity in right dorsolateral prefrontal circuitry. When activity in those circuits is absent or compromised subjects are less likely to make this kind of correction. This appears to be the cause of some delusions of misidentification consequent on experiences of hyperfamiliarity for faces. Comparing the way the mind responds to the experience of hyperfamiliarity in different conditions such as delusions, dreams, pathological and non pathological déjà vu, provides a way to understand claims that delusions and dreams are both states characterized by deficient reality testing.

Binge-type behavior in rats consuming trans-fat-free shortening.

Science.gov (United States)

Wojnicki, F H E; Charny, G; Corwin, R L W

2008-07-05

Studies from this and another laboratory involving an animal model of binge-type behavior have used vegetable shortening containing trans-fats. Due to reformulations by vegetable shortening manufacturers to remove trans-fats from their products, only trans-fat-free shortenings are now available. The goal of the present study was to assess binge-type behavior in rats with trans-fat and trans-free vegetable shortening. Trans-fat-free shortening was provided to three different groups of non-food-deprived male Sprague Dawley rats on different schedules of access: continuous access (24 h/day-7 days/week), daily access (1 h every day), and intermittent access (1 h on Mondays, Wednesdays, Fridays). Trans-fat shortening was provided to a fourth group on the intermittent access schedule. A fifth group had no shortening access (chow only). Both intermittent groups (trans-fat-free and trans-fat) consumed significantly more shortening during the 1-h period of availability than did the daily group, and there was no difference in shortening intakes between the intermittent groups. These results are identical to previous reports of binge-type behavior in rats using this model. Thus, binge-type behavior in the present behavioral model depends upon the schedule of access, not the presence of trans-fats in the shortening.

Pathologies of hyperfamiliarity in dreams, delusions and déjà vu.

Science.gov (United States)

Gerrans, Philip

2014-01-01

The ability to challenge and revise thoughts prompted by anomalous experiences depends on activity in right dorsolateral prefrontal circuitry. When activity in those circuits is absent or compromised subjects are less likely to make this kind of correction. This appears to be the cause of some delusions of misidentification consequent on experiences of hyperfamiliarity for faces. Comparing the way the mind responds to the experience of hyperfamiliarity in different conditions such as delusions, dreams, pathological and non-pathological déjà vu, provides a way to understand claims that delusions and dreams are both states characterized by deficient "reality testing."

Informační systém pro správu rezervací v restauracích

OpenAIRE

Slanař, David

2009-01-01

Tato bakalářská práce pojednává o stávajícím stavu fungování rezervací v restauracích a jeho inovaci pomocí zavedení informačního systému pro vytváření a správu rezervací. Popisuje návrh internetové webové aplikace umožňující on-line vytváření rezervací samotnými uživateli a jejich následnou správu zaměstnanci. Dále popis ekonomického přínosu a jiných výhod plynoucích ze zavedení tohoto systému v reálném světě a v neposlední řadě řešení případných problémů při nasazování systému v praxi. T...

[Extension of (extremely) shortened dental arches by fixed or removable partial dentures

NARCIS (Netherlands)

Witter, D.J.; Hoefnagel, R.A.; Snoek, P.A.; Creugers, N.H.J.

2009-01-01

Whether a shortened dental arch needs to be extended depends on the degree of the shortening. Four categories of shortened dental arches can be distinguished: 1. slightly shortened dental arches; 2. moderately shortened dental arches; 3. extremely shortened dental arches; and 4. asymmetrical

Challenges in the development of an M4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs.

Science.gov (United States)

Wood, Michael R; Noetzel, Meredith J; Poslusney, Michael S; Melancon, Bruce J; Tarr, James C; Lamsal, Atin; Chang, Sichen; Luscombe, Vincent B; Weiner, Rebecca L; Cho, Hyekyung P; Bubser, Michael; Jones, Carrie K; Niswender, Colleen M; Wood, Michael W; Engers, Darren W; Brandon, Nicholas J; Duggan, Mark E; Conn, P Jeffrey; Bridges, Thomas M; Lindsley, Craig W

2017-01-15

This letter describes the chemical optimization of a novel series of M 4 positive allosteric modulators (PAMs) based on a 5-amino-thieno[2,3-c]pyridazine core, developed via iterative parallel synthesis, and culminating in the highly utilized rodent in vivo tool compound, VU0467154 (5). This is the first report of the optimization campaign (SAR and DMPK profiling) that led to the discovery of VU0467154, and details all of the challenges faced in allosteric modulator programs (steep SAR, species differences in PAM pharmacology and subtle structural changes affecting CNS penetration). Copyright © 2016 Elsevier Ltd. All rights reserved.

Trénink hněvu: Smrtelný hřích v temperamentní profesi Coaching anger: A deadly sin in a lively profession

Directory of Open Access Journals (Sweden)

Jeffrey P. Fry

2006-02-01

Full Text Available Podle křesťanské tradice je hněv jedním ze "sedmi smrtelných hříchů". Ve východním náboženském myšlení je hněv považován za jedovatý a návykový. Tyto pohledy poukazují na problémovou povahu hněvu. Jiní se však domnívají, že hněv může nabývat vhodného výrazu a pozitivní funkce. Vzhledem k tomu, že hněv se ve sportu projevuje často, je důležité vyhodnotit význam hněvu také v této oblasti lidského života. Zvláště často projevují hněv trenéři. S ohledem na tuto skutečnost se v tomto příspěvku zaměřuji na povahu hněvu a jeho roli v profesi trenéra. Je na roli, kterou trenér zastává, něco, co by trenérům poskytovalo zvláštní svobodu ve vyjadřování hněvu? "Trénink hněvu" se nezabývá výhradně projevy hněvu trenérů, ale také praktickými kroky vedoucími k účinnému a přiměřenému ovládání této složité emoce. According to Christian tradition, anger comprises one of the "seven deadly sins". In Eastern religious thought anger is held to be poisonous and addictive. These views point to the problematic nature of anger. Some hold, however, that anger can have an appropriate expression and a positive function. Since anger is often vented in sport, it is important to assess the significance of anger in this area of life. Coaches, in particular, frequently display anger. Given this fact, in this paper I focus on the nature of anger and its role in the coaching profession. Is there something distinctive about the role of the coach such that coaches should be granted special leeway in the expression of anger? "Coaching anger" refers not merely to the manifestation of coaches’ anger, but also to practical steps towards effective and appropriate dealing with this complex emotion.

Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence.

Science.gov (United States)

Matsumoto, Ryusaku; Fukuoka, Hidenori; Iguchi, Genzo; Odake, Yukiko; Yoshida, Kenichi; Bando, Hironori; Suda, Kentaro; Nishizawa, Hitoshi; Takahashi, Michiko; Yamada, Shozo; Ogawa, Wataru; Takahashi, Yutaka

2015-01-01

Patients with acromegaly exhibit reduced life expectancy and increased prevalence of age-related diseases, such as diabetes, hypertension, and cardiovascular disease. However, the underlying mechanism has not been fully elucidated. Telomere shortening is reportedly associated with reduced life expectancy and increased prevalence of these age-related diseases. We measured telomere length in patients with acromegaly using quantitative PCR method. The effect of GH and IGF-I on telomere length and cellular senescence was examined in human skin fibroblasts. Patients with acromegaly exhibited shorter telomere length than age-, sex-, smoking-, and diabetes-matched control patients with non-functioning pituitary adenoma (0.62 ± 0.23 vs. 0.75 ± 0.35, respectively, P = 0.047). In addition, telomere length in acromegaly was negatively correlated with the disease duration (R2 = 0.210, P = 0.003). In vitro analysis revealed that not GH but IGF-I induced telomere shortening in human skin fibroblasts. Furthermore, IGF-I-treated cells showed increased senescence-associated β-galactosidase activity and expression of p53 and p21 protein. IGF-I-treated cells reached the Hayflick limit earlier than GH- or vehicle-treated cells, indicating that IGF-I induces cellular senescence. Shortened telomeres in acromegaly and cellular senescence induced by IGF-I can explain, in part, the underlying mechanisms by which acromegaly exhibits an increased morbidity and mortality in association with the excess secretion of IGF-I.

VuWiki: An Ontology-Based Semantic Wiki for Vulnerability Assessments

Science.gov (United States)

Khazai, Bijan; Kunz-Plapp, Tina; Büscher, Christian; Wegner, Antje

2014-05-01

The concept of vulnerability, as well as its implementation in vulnerability assessments, is used in various disciplines and contexts ranging from disaster management and reduction to ecology, public health or climate change and adaptation, and a corresponding multitude of ideas about how to conceptualize and measure vulnerability exists. Three decades of research in vulnerability have generated a complex and growing body of knowledge that challenges newcomers, practitioners and even experienced researchers. To provide a structured representation of the knowledge field "vulnerability assessment", we have set up an ontology-based semantic wiki for reviewing and representing vulnerability assessments: VuWiki, www.vuwiki.org. Based on a survey of 55 vulnerability assessment studies, we first developed an ontology as an explicit reference system for describing vulnerability assessments. We developed the ontology in a theoretically controlled manner based on general systems theory and guided by principles for ontology development in the field of earth and environment (Raskin and Pan 2005). Four key questions form the first level "branches" or categories of the developed ontology: (1) Vulnerability of what? (2) Vulnerability to what? (3) What reference framework was used in the vulnerability assessment?, and (4) What methodological approach was used in the vulnerability assessment? These questions correspond to the basic, abstract structure of the knowledge domain of vulnerability assessments and have been deduced from theories and concepts of various disciplines. The ontology was then implemented in a semantic wiki which allows for the classification and annotation of vulnerability assessments. As a semantic wiki, VuWiki does not aim at "synthesizing" a holistic and overarching model of vulnerability. Instead, it provides both scientists and practitioners with a uniform ontology as a reference system and offers easy and structured access to the knowledge field of

The role of nonlinear viscoelasticity on the functionality of laminating shortenings

Energy Technology Data Exchange (ETDEWEB)

Macias-Rodriguez, Braulio A.; Peyronel, Fernanda; Marangoni, Alejandro G.

2017-11-01

The rheology of fats is essential for the development of homogeneous and continuous layered structures of doughs. Here, we define laminating shortenings in terms of rheological behavior displayed during linear-to-nonlinear shear deformations, investigated by large amplitude oscillatory shear rheology. Likewise, we associate the rheological behavior of the shortenings with structural length scales elucidated by ultra-small angle x-ray scattering and cryo-electron microscopy. Shortenings exhibited solid-like viscoelastic and viscoelastoplastic behaviors in the linear and nonlinear regimes respectively. In the nonlinear region, laminating shortenings dissipated more viscous energy (larger normalized dynamic viscosities) than a cake bakery shortening. The fat solid-like network of laminating shortening displayed a three-hierarchy structure and layered crystal aggregates, in comparison to two-hierarchy structure and spherical-like crystal aggregates of a cake shortening. We argue that the observed rheology, correlated to the structural network, is crucial for optimal laminating performance of shortenings.

Représenter et penser l’affrontement : le magazine Vu face à la Guerre d’Espagne et à la menace d’une deuxième guerre mondiale

Directory of Open Access Journals (Sweden)

Sophie Kurkdjian

2011-04-01

Full Text Available Créé en 1928, Vu est un magazine qui confère à la photographie un nouveau rôle. Celle-ci constitue le propos même du magazine. Homme de gauche, son directeur, Lucien Vogel, est un pacifiste convaincu, dont le regard posé sur la période de l’entre-deux-guerres, plus précisément entre 1928 et 1936, est particulièrement intéressant à étudier. Cet article s’attachera à analyser la manière dont Vu couvre la Guerre d’Espagne et rapporte les tensions des années trente, héritées de la Première Guerre mondiale. Dans un premier temps, par l’intermédiaire de photographies et de mises en page destinées à marquer les esprits, Vu tente de prévenir un nouvel affrontement, la crainte d’une nouvelle guerre étant l’obsession de Lucien Vogel. Dans un second temps, lors de la Guerre d’Espagne, Vu prend, dès le début du conflit, fait et cause pour les Républicains espagnols. L’engagement de Lucien Vogel est tel qu’il est limogé par ses administrateurs qui lui reprochent d’avoir médiatisé l'événement avec un certain parti-pris. Ainsi, dans les deux cas, on se demandera jusqu’à quel point l’idéologie politique du directeur du magazine a un impact sur la représentation de cette période de crise et sur l’élaboration de la figure de l’ennemi. On montrera aussi que les nombreuses possibilités offertes par la photographie influencent la façon dont Lucien Vogel appréhende les événements de cette période.   Vu, created in 1928, is a magazine which endows photography with a new role, in that it became the very contents of the magazine. Its director, Lucien Vogel, is a convinced pacifist with left-wing commitments. His point of view on the period of time, in between the two world wars, is particularly interesting. Our article will study how, between 1928 and 1936, Vu reports the tensions inherited from World War I and covers the Spanish War.  In the first place, by means of photographs and eye

Pathologies of hyperfamiliarity in dreams, delusions and déjà vu

Science.gov (United States)

Gerrans, Philip

2014-01-01

The ability to challenge and revise thoughts prompted by anomalous experiences depends on activity in right dorsolateral prefrontal circuitry. When activity in those circuits is absent or compromised subjects are less likely to make this kind of correction. This appears to be the cause of some delusions of misidentification consequent on experiences of hyperfamiliarity for faces. Comparing the way the mind responds to the experience of hyperfamiliarity in different conditions such as delusions, dreams, pathological and non-pathological déjà vu, provides a way to understand claims that delusions and dreams are both states characterized by deficient “reality testing.” PMID:24600415

[Left atrial function and left atrial appendage flow velocity in hypertrophic cardiomyopathy: comparison of patients with and without paroxysmal atrial fibrillation].

Science.gov (United States)

Akasaka, K; Kawashima, E; Shiokoshi, T; Ishii, Y; Hasebe, N; Kikuchi, K

1998-07-01

The involvement of left atrial (LA) appendage flow velocity in reduced left atrial function was investigated in 24 patients with hypertrophic cardiomyopathy, who retained sinus rhythm at the examination. Patients were divided into 11 with a history of paroxysmal atrial fibrillation [PAf(+)] and 13 without such history [PAf(-)]. Transthoracic echocardiography was performed to evaluate LA fractional shortening (LA%FS) and mean velocity of circumferential LA fiber shortening (LAmVcf), as contractile functions of the left atrium at the phase of active atrial contraction. Transesophageal echocardiographic Doppler examination was performed in all patients to measure the LA appendage velocity. In all patients, significant positive correlations were observed between the LA appendage velocity and LA%FS (r = 0.50, p fibrillation were significantly lower than in those without (0.84 +/- 0.15 vs 1.28 +/- 0.37 circ/sec, 44 +/- 12 vs 65 +/- 20 cm/sec, both p fibrillation. These results indicate that there is a close relationship between LA appendage velocity and LA contractile function in patients with hypertrophic cardiomyopathy with paroxysmal atrial fibrilation, and these patients have potential risk of cerebral infarction.

Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence.

Directory of Open Access Journals (Sweden)

Ryusaku Matsumoto

Full Text Available Patients with acromegaly exhibit reduced life expectancy and increased prevalence of age-related diseases, such as diabetes, hypertension, and cardiovascular disease. However, the underlying mechanism has not been fully elucidated. Telomere shortening is reportedly associated with reduced life expectancy and increased prevalence of these age-related diseases.We measured telomere length in patients with acromegaly using quantitative PCR method. The effect of GH and IGF-I on telomere length and cellular senescence was examined in human skin fibroblasts.Patients with acromegaly exhibited shorter telomere length than age-, sex-, smoking-, and diabetes-matched control patients with non-functioning pituitary adenoma (0.62 ± 0.23 vs. 0.75 ± 0.35, respectively, P = 0.047. In addition, telomere length in acromegaly was negatively correlated with the disease duration (R2 = 0.210, P = 0.003. In vitro analysis revealed that not GH but IGF-I induced telomere shortening in human skin fibroblasts. Furthermore, IGF-I-treated cells showed increased senescence-associated β-galactosidase activity and expression of p53 and p21 protein. IGF-I-treated cells reached the Hayflick limit earlier than GH- or vehicle-treated cells, indicating that IGF-I induces cellular senescence.Shortened telomeres in acromegaly and cellular senescence induced by IGF-I can explain, in part, the underlying mechanisms by which acromegaly exhibits an increased morbidity and mortality in association with the excess secretion of IGF-I.

Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence

Science.gov (United States)

Matsumoto, Ryusaku; Fukuoka, Hidenori; Iguchi, Genzo; Odake, Yukiko; Yoshida, Kenichi; Bando, Hironori; Suda, Kentaro; Nishizawa, Hitoshi; Takahashi, Michiko; Yamada, Shozo; Ogawa, Wataru; Takahashi, Yutaka

2015-01-01

Objective Patients with acromegaly exhibit reduced life expectancy and increased prevalence of age-related diseases, such as diabetes, hypertension, and cardiovascular disease. However, the underlying mechanism has not been fully elucidated. Telomere shortening is reportedly associated with reduced life expectancy and increased prevalence of these age-related diseases. Methods We measured telomere length in patients with acromegaly using quantitative PCR method. The effect of GH and IGF-I on telomere length and cellular senescence was examined in human skin fibroblasts. Results Patients with acromegaly exhibited shorter telomere length than age-, sex-, smoking-, and diabetes-matched control patients with non-functioning pituitary adenoma (0.62 ± 0.23 vs. 0.75 ± 0.35, respectively, P = 0.047). In addition, telomere length in acromegaly was negatively correlated with the disease duration (R 2 = 0.210, P = 0.003). In vitro analysis revealed that not GH but IGF-I induced telomere shortening in human skin fibroblasts. Furthermore, IGF-I-treated cells showed increased senescence-associated β-galactosidase activity and expression of p53 and p21 protein. IGF-I-treated cells reached the Hayflick limit earlier than GH- or vehicle-treated cells, indicating that IGF-I induces cellular senescence. Conclusion Shortened telomeres in acromegaly and cellular senescence induced by IGF-I can explain, in part, the underlying mechanisms by which acromegaly exhibits an increased morbidity and mortality in association with the excess secretion of IGF-I. PMID:26448623

Aucun oeil ne l'a vu. Sur une force étrange d'agir pour les choses lointaines d'apres Levinas

Czech Academy of Sciences Publication Activity Database

Bierhanzl, Jan

2015-01-01

Roč. 11, č. 2 (2015) ISSN 1336-6556 R&D Projects: GA ČR(CZ) GAP401/10/1164 Institutional support: RVO:67985955 Keywords : invisibilty * utopia * action * subjectivity Subject RIV: AA - Philosophy ; Religion http://www.ostium.sk/sk/aucun-oeil-ne-la-vu/

Five-hole pitot probe time-mean velocity measurements in confined swirling flows

Science.gov (United States)

Yoon, H. K.; Lilley, D. G.

1983-01-01

Nonswirling and swirling nonreacting flows in an axisymmetric test section with an expansion ratio D/d = 2, which may be equipped with contraction nozzles of area ratios 2 and 4, are investigated. The effects of a number of geometric parameters on the flow-field are investigated, among them side-wall expansion angles of 90 and 45 deg, swirl vane angles of 0, 38, 45, 60, and 70 deg, and contraction nozzle locations L/D = 1 and 2 (if present). Data are acquired by means of a five-hole pitot probe enabling three time-mean velocity components in the axial, radial, and azimuthal directions to be measured. The velocities are extensively plotted and artistic impressions of recirculation zones are set forth. The presence of a swirler is found to shorten the corner recirculation zone and to generate a central recirculation zone followed by a precessing vortex core. A gradual inlet expansion has the effect of encouraging the flow to remain close to the sidewall and shortening the extent of the corner recirculation zone in all cases investigated.

Bone shortening of clavicular fractures

DEFF Research Database (Denmark)

Thorsmark, A H; Muhareb Udby, P; Ban, I

2017-01-01

BACKGROUND: The indication for operative treatment of clavicular fractures with bone shortening over 2 cm is much debated. Correct measurement of clavicular length is essential, and reliable measures of clavicular length are therefore highly requested by clinical decision-makers. The aim of this ......BACKGROUND: The indication for operative treatment of clavicular fractures with bone shortening over 2 cm is much debated. Correct measurement of clavicular length is essential, and reliable measures of clavicular length are therefore highly requested by clinical decision-makers. The aim......-fracture bone lengthening that indicated methodological problems. The Hill et al. and Silva et al. methods had high minimal detectable change, making their use unreliable. CONCLUSION: As all three measurement methods had either reliability or methodological issues, we found it likely that differences...

Shortening of construction period of nuclear power plant. Activities of construction industry on construction period shortening

International Nuclear Information System (INIS)

Kamata, Hirofumi

2011-01-01

Total construction period could be shorten by prefabricating structures efficiently in another yard and reducing working hours on site, which would reduce work at height or congestion work and also upgrade safety at work. Construction period shortening would surely reduce expenses during work and advance operation start of electric utilities. Construction of reactor building, turbine building, water intake and drainage canal was performed on a relatively large scale and a big share of whole schedule. This article summarized basic technologies to shorten construction period for reactor building/turbine building and water intake and drainage canal. Advanced methods of reactor building/turbine building; (1) modularization of equipment and skeleton, (2) utilization of concrete mold, reinforcing bar and steel frame, (3) precedent steel frame method and (4) steel plate reinforced concrete (SC) method, were outlined and their application examples were shown to reduce work on site and improve work efficiency. As for water intake and drainage canal construction, (1) precast concrete method, (2) SC method and (3) steel plate shell method were described with application examples. Construction procedures and problems using mega block method for water intake and drainage canal were also introduced. (T. Tanaka)

Physico-chemical properties and performance of high oleic and palm-based shortenings.

Science.gov (United States)

Ramli, Muhamad Roddy; Lin, Siew Wai; Yoo, Cheah Kien; Idris, Nor Aini; Sahri, Miskandar Mat

2008-01-01

Solid fat from fractionation of palm-based products was converted into cake shortening at different processing conditions. High oleic palm stearin with an oleic content of 48.2 % was obtained from fractionation of high oleic palm oil which was produced locally. Palm product was blended with different soft oils at pre-determined ratio and further fractionated to obtain the solid fractions. These fractions were then converted into cake shortenings named as high oleic, N1 and N2 blends. The physico-chemical properties of the experimental shortenings were compared with those of control shortenings in terms of fatty acid composition (FAC), iodine value (IV), slip melting point (SMP), solid fat content (SFC) and polymorphic forms. Unlike the imported commercial shortenings as reported by other studies and the control, experimental shortenings were trans-free. The SMP and SFC of experimental samples, except for the N2 sample, fell within the ranges of commercial and control shortenings. The IV was higher than those of domestic shortenings but lower when compared to imported and control shortenings. They were also observed to be beta tending even though a mixture of beta and beta' was observed in the samples after 3 months of storage. The shortenings were also used in the making of pound cake and sensory evaluation showed the good performance of high oleic sample as compared to the other shortenings.

Consequences of crown shortening canine teeth in Greenland sled dogs

DEFF Research Database (Denmark)

Kortegaard, H E; Anthony Knudsen, T; Dahl, S

2015-01-01

OBJECTIVES: To evaluate the consequences of crown shortening, focusing on the prevalence of pulp exposure and periapical pathology in Greenland sled dogs that had had their canine crowns shortened at an early age. METHODS: Five cadaver heads and 54 sled dogs underwent an oral examination for dental...... fractures and pulp exposure of canines. All canines were radiographed and evaluated for periapical pathology. RESULTS: The prevalence of canine pulp exposure in 12 (5 heads and 7 dogs) crown shortened dogs was 91 · 7%, and 21 · 3% in 47 not-crown shortened dogs. A significant (P pulp...... exposure of the canines in the crown shortened group compared to the not-crown shortened group was seen with a relative risk of 4 · 3 on a dog basis and a relative risk of 12 · 2 on a tooth basis. In dogs with pulp exposure of canines (n = 51) the prevalence of periapical pathology was 82 · 4%, but only 0...

Effect of selective attention on recollection and familiarity in recognition memory tasks: differential characteristics in patients with temporal lobe epilepsy with and without a history of déjà vu

OpenAIRE

Santamaría Gago, Paloma

2014-01-01

The most widely accepted contemporary explanation to define the phenomenon of déjà vu revolves around the processes of familiarity and recognition. This theoretical model is based on characteristics that define this experience in healthy subjects and in patients with temporal lobe epilepsy Objective: The main objective of this work is to determine the relationship between phenomenon of familiarity and phenomenon of recall according to the presence or absence of a history of déjà vu in p...

A study on occlusal stability in shortened dental arches.

Science.gov (United States)

Sarita, Paulo T N; Kreulen, Cees M; Witter, Dick J; van't Hof, Martin; Creugers, Nico H J

2003-01-01

The aim of this study was to verify the hypothesis that shortened dental arches constitute a risk to occlusal stability. Using cluster samples, 725 subjects with shortened dental arches comprising intact anterior regions and zero to eight occluding pairs of posterior teeth and 125 subjects with complete dental arches were selected. Subjects with shortened dental arches were classified into eight categories according to arch length and symmetry. Parameters for occlusal stability were interdental spacing, occlusal tooth wear, occlusal contact of incisors in intercuspal position, and vertical and horizontal overlap. Additionally, tooth mobility and overeruption of unopposed teeth were assessed. Influence of independent variables (dental arch category, age, gender, and residence) on the parameters for occlusal stability was assessed by one-way ANOVA and Tukey's multiple range tests. Extreme shortened dental arches (zero to two pairs of occluding premolars) had significantly more interdental spacing, occlusal contact of incisors, and vertical overlap compared to complete dental arches. Occlusal wear and prevalence of mobile teeth were highest in these categories. The category with three to four occluding premolars had significantly more interdental spacing and, for the older age group, more anterior teeth in occlusal contact compared to complete dental arches. Age was consistently associated with increased changes in occlusal integrity. Signs of increased risk to occlusal stability seemed to occur in extreme shortened dental arches, whereas no such evidence was found for intermediate categories of shortened dental arches.

Synergistic nonuniform shortening of atrial refractory period induced by autonomic stimulation.

Science.gov (United States)

Takei, M; Furukawa, Y; Narita, M; Ren, L M; Karasawa, Y; Murakami, M; Chiba, S

1991-12-01

We investigated the nonuniform effects of autonomic nerve stimulation of the effective refractory period (ERP) of the right atrium in the anesthetized dog. Stimulation of the discrete intracardiac sympathetic nerves to the sinoatrial (SA) nodal region uniformly shortened ERPs at three sites in the right atrium after administration of atropine. Right ansa subclavia (RS) stimulation similarly shortened ERPs in the absence of atropine. Stimulation of the discrete intracardiac parasympathetic nerves to the SA nodal region (SAP stimulation) shortened ERPs of the right atrium in a nonuniform manner. Simultaneous RS and SAP stimulation additively shortened ERPs at each site and decreased sinus rate much more than SAP stimulation alone. Shortening of ERP induced by SAP stimulation was greater than that induced by RS stimulation at similar absolute changes in heart rate. These results suggest that simultaneous activation of sympathetic and parasympathetic nerves nonuniformly shortens the ERP in the right atrium as the algebraic sum of the individual responses to each stimulation. However, parasympathetics exert the principal neural control over atrial ERP.

Instability during bunch shortening of an electron-cooled beam

Directory of Open Access Journals (Sweden)

M. Takanaka

2003-10-01

Full Text Available Bunch shortening causes an electron-cooled beam to be space charge dominated at low energies. Instability during the bunch shortening has been studied using a particle-tracking program where the 3D space-charge field due to the beam is calculated with a simplifying model.

A Shortened Stress Measure in Military Nursing Personnel

Science.gov (United States)

2017-10-17

REPORT TYPE 3. DATES COVERED (From- To) 10/17/2017 Abstract 4. TITLE AND SUBTITLE Sa. CONTRACT NUMBER A Shortened Stress Measure in Military...Psychology 14. ABSTRACT A Shortened Stress Measure with Military Nursing Personnel Abstract Stress is a psychological construct with important...consequences for human health. A substantial number of stress measures are available that vary in length and dimensionality. The purpose of this study was to

A generalized transport-velocity formulation for smoothed particle hydrodynamics

Energy Technology Data Exchange (ETDEWEB)

Zhang, Chi; Hu, Xiangyu Y., E-mail: xiangyu.hu@tum.de; Adams, Nikolaus A.

2017-05-15

The standard smoothed particle hydrodynamics (SPH) method suffers from tensile instability. In fluid-dynamics simulations this instability leads to particle clumping and void regions when negative pressure occurs. In solid-dynamics simulations, it results in unphysical structure fragmentation. In this work the transport-velocity formulation of Adami et al. (2013) is generalized for providing a solution of this long-standing problem. Other than imposing a global background pressure, a variable background pressure is used to modify the particle transport velocity and eliminate the tensile instability completely. Furthermore, such a modification is localized by defining a shortened smoothing length. The generalized formulation is suitable for fluid and solid materials with and without free surfaces. The results of extensive numerical tests on both fluid and solid dynamics problems indicate that the new method provides a unified approach for multi-physics SPH simulations.

Augmentation of Deglutitive Thyrohyoid Muscle Shortening by the Shaker Exercise

Science.gov (United States)

Mepani, Rachel; Antonik, Stephen; Massey, Benson; Kern, Mark; Logemann, Jerilyn; Pauloski, Barbara; Rademaker, Alfred; Easterling, Caryn

2010-01-01

Earlier studies of the effect of 6 weeks of the Shaker Exercise have shown significant increase in UES opening and anterior excursion of larynx and hyoid during swallowing in patients with upper esophageal sphincter (UES) dysfunction, resulting in elimination of aspiration and resumption of oral intake. This effect is attributed to strengthening of the suprahyoid muscles, as evidenced by comparison of electromyographic changes in muscle fatigue before and after completion of the exercise regime. The effect of this exercise on thyrohyoid muscle shortening is unknown. Therefore the aim of this study was to determine the effect of the exercise on thyrohyoid muscle shortening. We studied 11 dysphagic patients with UES dysfunction. Six were randomized to traditional swallowing therapy and five to the Shaker Exercise. Videofluoroscopy was used to measure deglutitive thyrohyoid shortening before and after completion of assigned therapy regimen. Maximum thyrohyoid muscle shortening occurred at close temporal proximity to the time of maximal thyroid cartilage excursion. The percent change in thyrohyoid distance from initiation of deglutition to maximal anterior/superior hyoid excursion showed no statistically significant difference between the two groups prior to either therapy (p = 0.54). In contrast, after completion of therapy, the percent change in thyrohyoid distance in the Shaker Exercise group was significantly greater compared to the traditional therapy (p = 0.034). The Shaker Exercise augments the thyrohyoid muscle shortening in addition to strengthening the suprahyoid muscles. The combination of increased thyrohyoid shortening and suprahyoid strengthening contributes to the Shaker Exercise outcome of deglutitive UES opening augmentation. PMID:18685891

Olanzapine induced Q-Tc shortening.

Science.gov (United States)

Shoja Shafti, Saeed; Fallah Jahromi, Parisa

2014-12-01

Prolongation of Q-Tc interval is commonly accepted as a surrogate marker for the ability of a drug to cause torsade de pointes. In the present study, safety of olanzapine versus risperidone was compared among a group of patients with schizophrenia to see the frequency of the electrocardiographic alterations induced by those atypical antipsychotics. Two hundred and sixty-eight female inpatients with schizophrenia entered in one of the two parallel groups to participate in an open study for random assignment to olanzapine (n = 148) or risperidone (n = 120). Standard 12-lead surface electrocardiogram (ECG) was taken from each patient at baseline, before initiation of treatment, and then at the end of management, just before discharge. The parameters that were assessed included heart rate (HR), P-R interval, QRS interval, Q-T interval (corrected = Q-Tc), ventricular activation time (VAT), ST segment, T wave, axis of QRS, and finally, interventricular conduction process. A total of 37.83% of cases in the olanzapine group and 30% in the risperidone group showed some Q-Tc changes; 13.51% and 24.32% of the patients in the olanzapine group showed prolongation and shortening of the Q-Tc, respectively, while changes in the risperidone group were restricted to only prolongation of Q-Tc. Comparison of means showed a significant increment in Q-Tc by risperidone (p = 0.02). Also, comparison of proportions in the olanzapine group showed significantly more cases with shortening of Q-Tc versus its prolongation (p = 0.01). No significant alterations with respect to other variables were evident. Olanzapine and risperidone had comparable potentiality for induction of Q-Tc changes, while production of further miscellaneous alterations in ECG was more observable in the olanzapine group compared with the risperidone group. Also shortening of Q-Tc was specific to olanzapine.

Shortening a loop can increase protein native state entropy.

Science.gov (United States)

Gavrilov, Yulian; Dagan, Shlomi; Levy, Yaakov

2015-12-01

Protein loops are essential structural elements that influence not only function but also protein stability and folding rates. It was recently reported that shortening a loop in the AcP protein may increase its native state conformational entropy. This effect on the entropy of the folded state can be much larger than the lower entropic penalty of ordering a shorter loop upon folding, and can therefore result in a more pronounced stabilization than predicted by polymer model for loop closure entropy. In this study, which aims at generalizing the effect of loop length shortening on native state dynamics, we use all-atom molecular dynamics simulations to study how gradual shortening a very long or solvent-exposed loop region in four different proteins can affect their stability. For two proteins, AcP and Ubc7, we show an increase in native state entropy in addition to the known effect of the loop length on the unfolded state entropy. However, for two permutants of SH3 domain, shortening a loop results only with the expected change in the entropy of the unfolded state, which nicely reproduces the observed experimental stabilization. Here, we show that an increase in the native state entropy following loop shortening is not unique to the AcP protein, yet nor is it a general rule that applies to all proteins following the truncation of any loop. This modification of the loop length on the folded state and on the unfolded state may result with a greater effect on protein stability. © 2015 Wiley Periodicals, Inc.

Compatibility of selected plant-based shortening as lard substitute: microstructure, polymorphic forms and textural properties

Directory of Open Access Journals (Sweden)

N. A.M. Yanty

2017-03-01

Full Text Available A study was carried out to determine the compatibility of three plant-based shortening mixtures to lard shortening (LD in terms of microstructure, polymorphic forms, and textural properties. The shortenings of binary, ternary, and quaternary fat mixtures were prepared according to a standard procedure by blending mee fat (MF with palm stearin (PS in a 99:1 (w/w ratio; avocado fat (Avo with PS and cocoa butter (CB in a 84:7:9 (w/w ratio; palm oil (PO with PS, soybean oil (SBO and CB in a 38:5:52:5 (w/w ratio, respectively. The triacylglycerol composition, polymorphic forms, crystal morphology, and textural properties of the shortening were evaluated. This study found that all three plant-based shortenings and LD shortening were similar with respect to their consistency, hardness and compression and adhesiveness values. However, all plant-based shortening was found to be dissimilar to LD shortening with respect to microstructure.

Compatibility of selected plant-based shortening as lard substitute: microstructure, polymorphic forms and textural properties

International Nuclear Information System (INIS)

Yanty, N.A.M.; Marikkar, J.M.N.; Miskandar, M.S.; Bockstaele, F. Van; Dewettinck, K.; Nusantoro, B.P.

2017-01-01

A study was carried out to determine the compatibility of three plant-based shortening mixtures to lard shortening (LD) in terms of microstructure, polymorphic forms, and textural properties. The shortenings of binary, ternary, and quaternary fat mixtures were prepared according to a standard procedure by blending mee fat (MF) with palm stearin (PS) in a 99:1 (w/w) ratio; avocado fat (Avo) with PS and cocoa butter (CB) in a 84:7:9 (w/w) ratio; palm oil (PO) with PS, soybean oil (SBO) and CB in a 38:5:52:5 (w/w) ratio, respectively. The triacylglycerol composition, polymorphic forms, crystal morphology, and textural properties of the shortening were evaluated. This study found that all three plant-based shortenings and LD shortening were similar with respect to their consistency, hardness and compression and adhesiveness values. However, all plant-based shortening was found to be dissimilar to LD shortening with respect to microstructure. [es

Cortical T2 signal shortening in amyotrophic lateral sclerosis is not due to iron deposits

Energy Technology Data Exchange (ETDEWEB)

Hecht, M.J.; Neundoerfer, B. [University of Erlangen-Nurenberg, Department of Neurology, Erlangen (Germany); Fellner, C.; Fellner, F.A. [University of Erlangen-Nurenberg, Institute of Diagnostic Radiology, Erlangen (Germany); Landes-Nervenklinik Wagner-Jauregg, Institute of Radiology, Linz (Austria); Schmid, A. [University of Erlangen-Nurenberg, Institute of Diagnostic Radiology, Erlangen (Germany)

2005-11-01

Signal shortening of the motor cortex in T2-weighted MR images is a frequent finding in patients with amyotrophic lateral sclerosis (ALS). The cause of signal shortening in ALS is unknown, although iron deposits have been suggested. To test this hypothesis, we acquired T2*-weighted gradient-echo (GRE) MR images in addition to T2-weighted turbo spin-echo in 69 patients with ALS. Signal shortening in T2-weighted images was found in 31 patients. In T2*-weighted GRE images, only three patients had signal shortening. One patient with additional bifrontal haemorrhage had frontal but no motor cortex signal shortening. Iron deposits do not cause cortical signal shortening in patients with ALS predominantly. Other factors are presumably more important in the generation of cortical T2 shortening in ALS. (orig.)

Cortical T2 signal shortening in amyotrophic lateral sclerosis is not due to iron deposits

International Nuclear Information System (INIS)

Hecht, M.J.; Neundoerfer, B.; Fellner, C.; Fellner, F.A.; Schmid, A.

2005-01-01

Signal shortening of the motor cortex in T2-weighted MR images is a frequent finding in patients with amyotrophic lateral sclerosis (ALS). The cause of signal shortening in ALS is unknown, although iron deposits have been suggested. To test this hypothesis, we acquired T2*-weighted gradient-echo (GRE) MR images in addition to T2-weighted turbo spin-echo in 69 patients with ALS. Signal shortening in T2-weighted images was found in 31 patients. In T2*-weighted GRE images, only three patients had signal shortening. One patient with additional bifrontal haemorrhage had frontal but no motor cortex signal shortening. Iron deposits do not cause cortical signal shortening in patients with ALS predominantly. Other factors are presumably more important in the generation of cortical T2 shortening in ALS. (orig.)

The awareness of novelty for strangely familiar words: a laboratory analogue of the déjà vu experience

OpenAIRE

Urquhart, Josephine A.; O’Connor, Akira R.

2014-01-01

Akira O’Connor is supported by a SINAPSE (Scottish Imaging Network: A Platform for Scientific Excellence) fellowship. Josephine Urquhart was supported by the University of St Andrews URIP Scheme. Déjà vu is a nebulous memory experience defined by a clash between evaluations of familiarity and novelty for the same stimulus. We sought to generate it in the laboratory by pairing a DRM recognition task, which generates erroneous familiarity for critical words, with a monitoring task by which p...

Lateral mobility of minibasins during shortening: Insights from the SE Precaspian Basin, Kazakhstan

Science.gov (United States)

Duffy, Oliver B.; Fernandez, Naiara; Hudec, Michael R.; Jackson, Martin P. A.; Burg, George; Dooley, Tim P.; Jackson, Christopher A.-L.

2017-04-01

Minibasin provinces are widespread and can be found in all types of salt tectonic settings, many of which are prone to shortening. Previous studies of how minibasin provinces shorten assume that the salt between the minibasins is homogeneous and that the base of salt is flat or of low relief, such that minibasins are free to move laterally. Here we investigate how minibasin provinces respond to shortening when the lateral mobility of the minibasins is restricted by intra-salt sediment bodies, in order to gain a greater understanding of the controls on the structural styles and modes of tectono-stratigraphic evolution exhibited in minibasin provinces. We examine a borehole-constrained, 3D seismic reflection dataset from the SE Precaspian Basin (onshore western Kazakhstan). The study area is characterised by large, supra-salt minibasins and an array of smaller intra-salt sediment packages distributed between these larger minibasins. We first outline the evidence of episodic shortening between the Late Triassic and present, after the onset of supra-salt minibasin subsidence. Next, we document spatial variations in shortening style, showing how these relate to the concentration of intra-salt sediment packages. Finally, we develop synoptic models showing how intra-salt sediment packages influence both the lateral mobility of minibasins during shortening and the resultant structural style, and we compare and contrast our findings with existing models and other natural examples of shortened minibasin provinces. We conclude that minibasin provinces may have different degrees of lateral mobility depending on the presence, or absence, of intrasalt barriers, and that these variations provide a first-order control on basin-shortening style and tectono-stratigraphic evolution.

Continental lithospheric subduction and intermediate-depth seismicity: Constraints from S-wave velocity structures in the Pamir and Hindu Kush

Science.gov (United States)

Li, Wei; Chen, Yun; Yuan, Xiaohui; Schurr, Bernd; Mechie, James; Oimahmadov, Ilhomjon; Fu, Bihong

2018-01-01

The Pamir has experienced more intense deformation and shortening than Tibet, although it has a similar history of terrane accretion. Subduction as a primary way to accommodate lithospheric shortening beneath the Pamir has induced the intermediate-depth seismicity, which is rare in Tibet. Here we construct a 3D S-wave velocity model of the lithosphere beneath the Pamir by surface wave tomography using data of the TIPAGE (Tien Shan-Pamir Geodynamic program) and other seismic networks in the area. We imaged a large-scale low velocity anomaly in the crust at 20-50 km depth in the Pamir overlain by a high velocity anomaly at a depth shallower than 15 km. The high velocity anomalies colocate with exposed gneiss domes, which may imply a similar history of crustal deformation, partial melting and exhumation in the hinterland, as has occurred in the Himalaya/Tibet system. At mantle depths, where the intermediate-depth earthquakes are located, a low velocity zone is clearly observed extending to about 180 km and 150 km depth in the Hindu Kush and eastern Pamir, respectively. Moreover, the geometry of the low-velocity anomaly suggests that lower crustal material has been pulled down into the mantle by the subducting Asian and Indian lithospheric mantle beneath the Pamir and Hindu Kush, respectively. Metamorphic processes in the subducting lower crust may cause the intermediate-depth seismicity down to 150-180 km depth beneath the Pamir and Hindu Kush. We inverted focal mechanisms in the seismic zone for the stress field. Differences in the stress field between the upper and lower parts of the Indian slab imply that subduction and detachment of the Indian lithosphere might cause intense seismicity associated with the thermal shear instability in the deep Hindu Kush.

A structural and kinetic study on myofibrils prevented from shortening by chemical cross-linking.

Science.gov (United States)

Herrmann, C; Sleep, J; Chaussepied, P; Travers, F; Barman, T

1993-07-20

In previous work, we studied the early steps of the Mg(2+)-ATPase activity of Ca(2+)-activated myofibrils [Houadjeto, M., Travers, F., & Barman, T. (1992) Biochemistry 31, 1564-1569]. The myofibrils were free to contract, and the results obtained refer to the ATPase cycle of myofibrils contracting with no external load. Here we studied the ATPase of myofibrils contracting isometrically. To prevent shortening, we cross-linked them with 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC). SDS-PAGE and Western blot analyses showed that the myosin rods were extensively cross-linked and that 8% of the myosin heads were cross-linked to the thin filament. The transient kinetics of the cross-linked myofibrils were studied in 0.1 M potassium acetate, pH 7.4 and 4 degrees C, by the rapid-flow quench method. The ATP binding steps were studied by the cold ATP chase and the cleavage and release of products steps by the Pi burst method. In Pi burst experiments, the sizes of the bursts were equal within experimental error to the ATPase site concentrations (as determined by the cold ATP chase methods) for both cross-linked (isometric) and un-cross-linked (isotonic) myofibrils. This shows that in both cases the rate-limiting step is after the cleavage of ATP. When cross-linked, the kcat of Ca(2+)-activated myofibrils was reduced from 1.7 to 0.8 s-1. This is consistent with the observation that fibers shortening at moderate velocity have a higher ATPase activity than isometric fibers.(ABSTRACT TRUNCATED AT 250 WORDS)

Telomere Shortening in Neurological Disorders: An Abundance of Unanswered Questions

OpenAIRE

Eitan, Erez; Hutchison, Emmette R.; Mattson, Mark P.

2014-01-01

Telomeres, ribonucleoprotein complexes that cap eukaryotic chromosomes, typically shorten in leukocytes with aging. Aging is a primary risk factor for neurodegenerative disease (ND), and a common assumption has arisen that leukocyte telomere length (LTL) can serve as a predictor of neurological disease. However, the evidence for shorter LTL in Alzheimer’s and Parkinson’s patients is inconsistent. The diverse causes of telomere shortening may explain variability in LTL between studies and indi...

Limitations on Inferring 3D Architecture and Dynamics From Surface Velocities in the India-Eurasia Collision Zone

Science.gov (United States)

Flesch, L.; Bendick, R.; Bischoff, S.

2018-02-01

Surface velocities derived from Global Positioning System observations and Quaternary fault slip rates measured throughout an extended region of high topography in South Asia vary smoothly over thousands of kilometers and are broadly symmetrical, with components of both north-south shortening and east-west extension relative to stable Eurasia. The observed velocity field does not contain discontinuities or steep gradients attributable to along-strike differences in collision architecture, despite the well-documented presence of a lithospheric slab beneath the Pamir but not the Tibetan Plateau. We use a modified Akaike information criterion (AICc) to show that surface velocities do not efficiently constrain 3D rheology, geometry, or force balance. Therefore, although other geophysical and geological observations may indicate the presence of mechanical or dynamic heterogeneities within the Indian-Asian collision, the surface Global Positioning System velocities contain little or no usable information about them.

Lengthening of the shortened first metatarsal after Wilson's osteotomy for hallux valgus.

Science.gov (United States)

Singh, D; Dudkiewicz, I

2009-12-01

Metatarsalgia is a recognised complication following iatrogenic shortening of the first metatarsal in the management of hallux valgus. The traditional surgical treatment is by shortening osteotomies of the lesser metatarsals. We describe the results of lengthening of iatrogenic first brachymetatarsia in 16 females. A Scarf-type osteotomy was used in the first four cases and a step-cut of equal thicknesses along the axis of the first metatarsal was performed in the others. The mean follow-up was 21 months (19 to 26). Relief of metatarsalgia was obtained in the six patients in whom 10 mm of lengthening had been achieved, compared to only 50% relief in those where less than 8 mm of lengthening had been gained. One-stage step-cut lengthening osteotomy of the first metatarsal may be preferable to shortening osteotomies of the lesser metatarsals in the treatment of metatarsalgia following surgical shortening of the first metatarsal.

Thickening the outer margins of the Tibetan Plateau: The role of crustal shortening

Science.gov (United States)

Lease, R. O.; Burbank, D. W.

2012-12-01

One of the most direct consequences of the collision of two buoyant continents is large-scale crustal thickening that results in the upward and outward growth of high terrain. As the stronger Indian continent has collided with weaker Asia over at least the past 50 Myr, widespread crustal thickening has occurred over an area that is approximately 2.5 million km^2 at present. The resultant Tibetan crust is the thickest observed on Earth today with an average thickness of 65 km and a maximum that may reach 90 km in places. The mechanisms by which Tibetan crust has thickened, however, as well as the timing and distribution of these mechanisms across the plateau, remain debatable. Two of the most popular mechanisms for thickening the crust beneath the margins of the Tibetan Plateau are: 1) pure shear with faulting and folding in the upper crust and horizontal shortening below; and 2) flow and inflation of lower or middle crust without significant shortening of the upper crust. To help discriminate between the relative contributions of these two mechanisms, well-constrained estimates of upper crustal shortening are needed. Here we document the Cenozoic shortening budget across the northeastern Tibetan Plateau margin near 36°N 102.5°E with several 100- to 145-km-long balanced cross sections. Thermochronological and magnetostratigraphic data indicate that modest NNE-SSW shortening began in middle Eocene time, shortly after initial India-Asia collision. Accelerated east-west shortening, however, did not commence until ~35 Myr later. A five-fold acceleration in shortening rates in middle Miocene-to-Recent time accounts for more than half of the total Cenozoic crustal shortening and thickening in this region. Overall, the balanced cross sections indicate 11 ± 2 % east-west shortening since middle Miocene time, and ~9 ± 2 % NNE-SSW shortening between middle Eocene and middle Miocene times. Given the present-day crustal thickness of 56 ± 4 km in northeastern Tibet, crustal

Crustal balance and crustal flux from shortening estimates in the Central Andes

Science.gov (United States)

Hindle, David; Kley, Jonas; Oncken, Onno; Sobolev, Stephan

2005-01-01

The Central Andes of South America form the second largest high elevation plateau on earth. Extreme elevations have formed on a noncollisional margin with abundant associated arc magmatism. It has long been thought that the crustal thickness necessary to support Andean topography was not accounted for by known crustal shortening alone. We show that this may in part be due to a two-dimensional treatment of the problem. A three-dimensional analysis of crustal shortening and crustal thickness shows that displacement of material towards the axis of the bend in the Central Andes has added a significant volume of crust not accounted for in previous comparisons. We find that present-day crustal thickness between 12°S and 25°S is accounted for (∼-10% to ∼+3%)with the same shortening estimates, and the same assumed initial crustal thickness as had previously led to the conclusion of a ∼25-35% deficit in shortening relative to volume of crustal material. We suggest that the present-day measured crustal thickness distribution may not match that predicted due to shortening, and substantial redistribution of crust may have occurred by both erosion and deposition at the surface and lower crustal flow in regions of the thermally weakened middle and lower crust.

Influence of muscle geometry on shortening speed of fibre, aponeurosis and muscle

NARCIS (Netherlands)

Zuurbier, C. J.; Huijing, P. A.

1992-01-01

The influence of muscle geometry on muscle shortening of the gastrocnemius medialis muscle (GM) of the rat was studied. Using cinematography, GM geometry was studied during isokinetic concentric activity at muscle lengths ranging from 85 to 105% of the optimum muscle length. The shortening speed of

Analyzing the Velocity of Vegetation Phenology Over the Tibetan Plateau Using Gimms NDVI3g Data

Science.gov (United States)

Zhou, Y. K.

2018-05-01

Global environmental change is rapidly altering the dynamics of terrestrial vegetation, and phenology is a classic proxy to detect the response of vegetation to the changes. On the Tibetan Plateau, the earlier spring and delayed autumn vegetation phenology is widely reported. Remotely sensed NDVI can serve as a good data source for vegetation phenology study. Here GIMMS NDVI3g data was used to detect vegetation phenology status on the Tibetan Plateau. The spatial and temporal gradients are combined to depict the velocity of vegetation expanding process. This velocity index represents the instantaneous local velocity along the Earth's surface needed to maintain constant vegetation condition. This study found that NDVI velocity show a complex spatial pattern. A considerable number of regions display a later starting of growing season (SOS) and earlier end of growing season (EOS) reflected by the velocity change, particularly in the central part of the plateau. Nearly 74 % vegetation experienced a shortened growing season length. Totally, the magnitude of the phenology velocity is at a small level that reveals there is not a significant variation of vegetation phenology under the climate change context.

Shortened stapedius tendon: a rare cause of conductive hearing loss.

Science.gov (United States)

Zawawi, F; Varshney, R; Schloss, M D

2014-01-01

Anomalies of the stapedius tendon have been reported to cause conductive hearing loss; in theory, such anomalies limit the movement of the stapes. To demonstrate a rare cause of conductive hearing loss resulting from anomaly of the stapedius tendon and to compare the clinical findings of this patient to other stapedius tendon anomalies reported in the literature. Case report of a single case of shortened stapedius tendon and a review of the English literature on stapedius tendon anomalies. This is a case report of a 15-year-old boy with shortened stapedius tendon causing unilateral hearing loss, accompanied by a review of the literature. Contrary to other reported cases, this patient did not have an ossified tendon, but rather an extremely short tendon. The boy regained normal hearing following excision of the stapedius tendon. A shortened stapedius tendon is a very rare diagnosis, yet it should be considered as a possible cause of conductive hearing loss.

Comparison of vegetable shortening and cocoa butter as vehicles for cortisol manipulation in Salmo trutta

DEFF Research Database (Denmark)

Birnie-Gauvin, Kim; Peiman, K. S.; Larsen, M. H.

2018-01-01

This study demonstrates that vegetable shortening and cocoa butter are two effective vehicles for intraperitoneal cortisol implants in juvenile teleosts, specifically brown trout Salmo trutta, residing in north temperate freshwater environments. Each vehicle showed a different pattern of cortisol...... elevation. Vegetable shortening was found to be a more suitable vehicle for long-term cortisol elevation [elevated at 3, 6 and 9 days post treatment (dpt)], while cocoa butter may be better suited for short-term cortisol elevation (only elevated at 3 dpt). Additionally, plasma cortisol levels were higher...... with cortisol–vegetable shortening than with cortisol–cocoa butter implants. Plasma glucose levels were elevated 6 and 9 dpt for fishes injected with cortisol–vegetable shortening, but did not change relative to controls and shams in cortisol–cocoa butter fishes. In conclusion, vegetable shortening and cocoa...

How does ulnar shortening osteotomy influence morphologic changes in the triangular fibrocartilage complex?

Science.gov (United States)

Yamanaka, Yoshiaki; Nakamura, Toshiyasu; Sato, Kazuki; Toyama, Yoshiaki

2014-11-01

Ulnar shortening osteotomy often is indicated for treatment of injuries to the triangular fibrocartilage complex (TFCC). However, the effect of ulnar shortening osteotomy on the changes in shape of the TFCC is unclear. In our study, quantitative evaluations were performed using MRI to clarify the effect of ulnar shortening on triangular fibrocartilage (TFC) thickness attributable to disc regeneration of the TFC and TFC angle attributable to the suspension effect of ulnar shortening on the TFC. The purposes of this study were (1) to compare preoperative and postoperative TFC thickness and TFC angle on MR images to quantitatively evaluate the effect of ulnar shortening osteotomy on disc regeneration and the suspension effect on the TFC; and (2) to assess whether changes in TFC thickness and TFC angle correlated with the Mayo wrist score. Between 1995 and 2008, 256 patients underwent ulnar shortening osteotomy for TFCC injuries. The minimum followup was 24 months (mean, 51 months; range, 24-210 months). A total of 79 patients (31%) with complete followup including preoperative and postoperative MR images and the Mayo wrist score was included in this retrospective study. Evaluation of the postoperative MR images and the Mayo wrist score were performed at the final followup. The remaining 177 patients did not undergo postoperative MRI, or they had a previous fracture, large tears of the disc proper, or were lost to followup. Two orthopaedists, one of whom performed the surgeries, measured the TFC thickness and the TFC angle on coronal MR images before and after surgery for each patient. Correlations of the percent change in the TFC thickness and the magnitude of TFC angle change with age, sex, postoperative MR images, extent of ulnar shortening, preoperative ulnar variance, and postoperative Mayo wrist score were assessed. Stepwise regression analysis showed a correlation between the percent change in TFC thickness and preoperative ulnar variance (R2=0.21; β=-0.33; 95

Masticatory Efficiency of Shortened Dental Arch Subjects with ...

African Journals Online (AJOL)

2017-05-16

May 16, 2017 ... of shortened dental arch subjects with removable partial denture: A comparative ... at the post- and pre-treatment phases was statistically significant (P = 0.001). The .... after the delivery of metal-based RPD with the denture in.

A Shortened versus Standard Matched Postpartum Magnesium ...

African Journals Online (AJOL)

Magnesium sulphate is currently the most ideal drug for the treatment of eclampsia but its use in Nigeria is still limited due its cost and clinicians inexperience with the drug. The purpose of this study was to determine whether a shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard ...

Telomere shortening and survival in free-living corvids

NARCIS (Netherlands)

Salomons, H.M.; Mulder, G.A.; Zande, L. van de; Haussmann, M.F.; Linskens, M.H.K.; Verhulst, S.

2009-01-01

Evidence accumulates that telomere shortening reflects lifestyle and predicts remaining lifespan, but little is known of telomere dynamics and their relation to survival under natural conditions. We present longitudinal telomere data in free-living jackdaws (Corvus monedula) and test hypotheses on

Shortening and Thickening of Metropolitan Los Angeles Measured and Inferred Using Geodesy

Science.gov (United States)

Argus, D.; Heflin, M.; Donnellan, A.; Webb, F.; Dong, D.; Hurst, K.; Jefferson, D.; Lyzenga, G.; Watkins, M.; Zumberge, J.

1999-01-01

Geodetic measurements using the Global Positioning System and other techniques show north-south shortening near Los Angeles to be fastest across the northern part of the metropolitan area, where an ESE-striking, 5- to 40-km-wide belt lying to the south of San Gabriel Mountains and to the north of downtown and West Los Angeles is shortening at 5 mm/yr.

Veterans before the European Court of Human Rights: Vučković and others against Serbia

Directory of Open Access Journals (Sweden)

Rašević Živorad

2015-01-01

Full Text Available This paper investigates the case of Boban Vučković and others before the Serbian judiciary, Constitutional Court of Serbia and the European Court of Human Rights, which was induced by Serbian Government's lack of recognition of the right to a fair remuneration to the military reservists-veterans of the armed conflict in 1999. in former Yugoslavia. The judicial restrictive approach in interpretation and application of anti-discirimination law norms (contrary to the principle iura novit curia was criticized. Certain solutions were proposed in accordance with international standards, based on non-discriminatory treatment of military reservists in relation to other persons who perform public service, and on obligation to a just satisfaction due to violation of personality rights contained in physical and psychological attrition in military service during the war.

Shortened duration of untreated first episode of psychosis

DEFF Research Database (Denmark)

Larsen, Tor Ketil; McGlashan, T H; Johannessen, Jan Olav

2001-01-01

OBJECTIVE: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment. METHOD: Two study groups were ascertained in the same Norwegian h...

Comparison of vegetable shortening and cocoa butter as vehicles for cortisol manipulation in Salmo trutta.

Science.gov (United States)

Birnie-Gauvin, K; Peiman, K S; Larsen, M H; Aarestrup, K; Gilmour, K M; Cooke, S J

2018-01-01

This study demonstrates that vegetable shortening and cocoa butter are two effective vehicles for intraperitoneal cortisol implants in juvenile teleosts, specifically brown trout Salmo trutta, residing in north temperate freshwater environments. Each vehicle showed a different pattern of cortisol elevation. Vegetable shortening was found to be a more suitable vehicle for long-term cortisol elevation [elevated at 3, 6 and 9 days post treatment (dpt)], while cocoa butter may be better suited for short-term cortisol elevation (only elevated at 3 dpt). Additionally, plasma cortisol levels were higher with cortisol-vegetable shortening than with cortisol-cocoa butter implants. Plasma glucose levels were elevated 6 and 9 dpt for fishes injected with cortisol-vegetable shortening, but did not change relative to controls and shams in cortisol-cocoa butter fishes. In conclusion, vegetable shortening and cocoa butter are both viable techniques for cortisol manipulation in fishes in temperate climates, providing researchers with different options depending on study objectives. © 2017 The Fisheries Society of the British Isles.

Shortened Lifespan and Lethal Hemorrhage in a Hemophilia A Mouse Model.

Science.gov (United States)

Staber, Janice M; Pollpeter, Molly J

2016-01-01

Hemophilia A animal models have helped advance our understanding of factor VIII deficiency. Previously, factor VIII deficient mouse models were reported to have a normal life span without spontaneous bleeds. However, the bleeding frequency and survival in these animals has not been thoroughly evaluated. To investigate the survival and lethal bleeding frequency in two strains of E-16 hemophilia A mice. We prospectively studied factor VIII deficient hemizygous affected males (n = 83) and homozygous affected females (n = 55) for survival and bleeding frequency. Animals were evaluated for presence and location of bleeds as potential cause of death. Hemophilia A mice had a median survival of 254 days, which is significantly shortened compared to wild type controls (p hemophilia A mice experienced hemorrhage in several tissues. This previously-underappreciated shortened survival in the hemophilia A murine model provides new outcomes for investigation of therapeutics and also reflects the shortened lifespan of patients if left untreated.

Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span.

Science.gov (United States)

Martin-Ruiz, Carmen; Saretzki, Gabriele; Petrie, Joanne; Ladhoff, Juliane; Jeyapalan, Jessie; Wei, Wenyi; Sedivy, John; von Zglinicki, Thomas

2004-04-23

The replicative life span of human fibroblasts is heterogeneous, with a fraction of cells senescing at every population doubling. To find out whether this heterogeneity is due to premature senescence, i.e. driven by a nontelomeric mechanism, fibroblasts with a senescent phenotype were isolated from growing cultures and clones by flow cytometry. These senescent cells had shorter telomeres than their cycling counterparts at all population doubling levels and both in mass cultures and in individual subclones, indicating heterogeneity in the rate of telomere shortening. Ectopic expression of telomerase stabilized telomere length in the majority of cells and rescued them from early senescence, suggesting a causal role of telomere shortening. Under standard cell culture conditions, there was a minor fraction of cells that showed a senescent phenotype and short telomeres despite active telomerase. This fraction increased under chronic mild oxidative stress, which is known to accelerate telomere shortening. It is possible that even high telomerase activity cannot fully compensate for telomere shortening in all cells. The data show that heterogeneity of the human fibroblast replicative life span can be caused by significant stochastic cell-to-cell variation in telomere shortening.

Effect of movement velocity on the relationship between training load and the number of repetitions of bench press.

Science.gov (United States)

Sakamoto, Akihiro; Sinclair, Peter J

2006-08-01

This study investigated the effect of movement velocity on the relationship between loading intensity and the number of repetitions of bench press. Thirteen healthy men (age = 21.7 +/- 1.0 years; weight = 76.8 +/- 2.5 kg; 1 repetition maximum [1RM] = 99.5 +/- 6.0 kg), who were involved in regular weight training, voluntarily participated in the experiment. Subjects performed bench presses on a Smith machine at 5 different intensities (40-80% 1RM), repeated for 4 velocity conditions (slow: 0.15 +/- 0.03 m.s(-1); medium: 0.32 +/- 0.07 m.s(-1); fast: 0.52 +/- 0.12 m.s(-1); ballistic: maximum velocity), which were randomly assigned over 5 experimental sessions after a 1RM test. Velocity significantly changed the relationship between intensity (%1RM) and the number of reps performed (p velocities producing a higher number of reps. A significant interaction between intensity and velocity meant that velocity had a much greater effect on repetitions at lower intensities. These results suggest that the benefits of using a stretch-shortening cycle during faster movements outweigh the associated disadvantages from the force-velocity relationship. The practical applications of this study are that, when trainees are assigned a resistance training with specific RM values, the lifted intensity (%1RM) or weights will not be consistent unless velocity is controlled during training.

Molecular-dynamics simulation of crystalline 18-crown-6: thermal shortening of covalent bonds

NARCIS (Netherlands)

van Eerden, J.; Harkema, Sybolt; Feil, D.

1990-01-01

Molecular-dynamics simulations of crystalline 18-crown-6 have been performed in a study of the apparent thermal shortening of covalent bonds observed in crystal structures. At 100 K, a shortening of 0.006 _+ 0.001 A for C----C and C----O bonds was obtained. This result was found to be independent of

Common Patterns of Congenital Lower Extremity Shortening: Diagnosis, Classification, and Follow-up.

Science.gov (United States)

Bedoya, Maria A; Chauvin, Nancy A; Jaramillo, Diego; Davidson, Richard; Horn, B David; Ho-Fung, Victor

2015-01-01

Congenital lower limb shortening is a group of relatively rare, heterogeneous disorders. Proximal focal femoral deficiency (PFFD) and fibular hemimelia (FH) are the most common pathologic entities in this disease spectrum. PFFD is characterized by variable degrees of shortening or absence of the femoral head, with associated dysplasia of the acetabulum and femoral shaft. FH ranges from mild hypoplasia to complete absence of the fibula with variable shortening of the tibia. The development of the lower limb requires complex and precise gene interactions. Although the etiologies of PFFD and FH remain unknown, there is a strong association between the two disorders. Associated congenital defects in the lower extremity are found in more than 50% of patients with PFFD, ipsilateral FH being the most common. FH also has a strong association with shortening and bowing of the tibia and with foot deformities such as absence of the lateral rays of the foot. Early diagnosis and radiologic classification of these abnormalities are imperative for appropriate management and surgical planning. Plain radiography remains the main diagnostic imaging modality for both PFFD and FH, and appropriate description of the osseous abnormalities seen on radiographs allows accurate classification, prognostic evaluation, and surgical planning. Minor malformations may commonly be misdiagnosed. ©RSNA, 2015.

L-Carnosine reduces telomere damage and shortening rate in cultured normal fibroblasts

International Nuclear Information System (INIS)

Shao Lan; Li Qinghuan; Tan Zheng

2004-01-01

Telomere is the repetitive DNA sequence at the end of chromosomes, which shortens progressively with cell division and limits the replicative potential of normal human somatic cells. L-Carnosine, a naturally occurring dipeptide, has been reported to delay the replicative senescence, and extend the lifespan of cultured human diploid fibroblasts. In this work, we studied the effect of carnosine on the telomeric DNA of cultured human fetal lung fibroblast cells. Cells continuously grown in 20 mM carnosine exhibited a slower telomere shortening rate and extended lifespan in population doublings. When kept in a long-term nonproliferating state, they accumulated much less damages in the telomeric DNA when cultured in the presence of carnosine. We suggest that the reduction in telomere shortening rate and damages in telomeric DNA made an important contribution to the life-extension effect of carnosine

Compression and Combining Based on Channel Shortening and Rank Reduction Technique for Cooperative Wireless Sensor Networks

KAUST Repository

Ahmed, Qasim Zeeshan

2013-12-18

This paper investigates and compares the performance of wireless sensor networks where sensors operate on the principles of cooperative communications. We consider a scenario where the source transmits signals to the destination with the help of L sensors. As the destination has the capacity of processing only U out of these L signals, the strongest U signals are selected while the remaining (L?U) signals are suppressed. A preprocessing block similar to channel-shortening is proposed in this contribution. However, this preprocessing block employs a rank-reduction technique instead of channel-shortening. By employing this preprocessing, we are able to decrease the computational complexity of the system without affecting the bit error rate (BER) performance. From our simulations, it can be shown that these schemes outperform the channel-shortening schemes in terms of computational complexity. In addition, the proposed schemes have a superior BER performance as compared to channel-shortening schemes when sensors employ fixed gain amplification. However, for sensors which employ variable gain amplification, a tradeoff exists in terms of BER performance between the channel-shortening and these schemes. These schemes outperform channel-shortening scheme for lower signal-to-noise ratio.

Life-shortening and carcinogenesis in mice irradiated neonatally with x rays

International Nuclear Information System (INIS)

Sasaki, S.; Kasuga, T.

1981-01-01

The characteristics of life-shortening and carcinogenesis were investigated in x-irradiated neonatal B6WFr mice. Animals were irradiated with 24 hr after birth and allowed to complete their normal life span. Mean life span was shortened linearly with doses at a rate of 9.1% per 100 R for females and 9.8% for males. The spectrum of neoplastic diseases was apparently modulated by x irradiation, showing neonatal B6WFr mice to be highly susceptible to the induction of thymic lymphoma, liver tumor, and pituitary tumor. The dose-response relationship for thymice lymphoma could be described by a linear-quadratic model, and linearity could be rejected. Thymic lymphoma developed after a short latent period, resulting in death between 100 and 450 days of age. Liver and pituitary tumors increased with increasing dose up to 400 R and decreased thereafter. The latent period for liver tumor development was apparently shortened with increasing doses. Pituitary tumor developed in excess only in females after a long latent period

Masticatory efficiency of shortened dental arch subjects with ...

African Journals Online (AJOL)

Objective: The objective of this study was to compare the masticatory efficiency in subjects with shortened dental arch (SDA) before and after restoration with removable partial denture (RPD). Materials and Methods: This was a prospective study carried out on 36 consecutive patients. The subjects were asked to chew 5 g of ...

Effect of shortening replacement with oleogels on the rheological and tomographic characteristics of aerated baked goods.

Science.gov (United States)

Lim, Jeongtaek; Jeong, Sungmin; Lee, JaeHwan; Park, Sungkwon; Lee, Jonggil; Lee, Suyong

2017-08-01

A great deal of effort has been made to reduce the use of shortening owing to the high level of saturated fats as well as the presence of trans fats. Grape seed oil high in unsaturated fats was structured with candelilla wax to form solid-like oleogels that were utilized as a shortening replacer in aerated baked goods, specifically muffins. Muffin batters with greater amounts of oleogels exhibited lower viscosity, greater shear-thinning behavior and less elastic nature. The shortening replacement with oleogels significantly increased the specific gravity of the batters, consequently affecting the muffin volume after baking. X-ray tomography indicated a lower fragmentation index (i.e. a more connected solid structure) in the oleogel-incorporated muffins, which was correlated with more enclosed and isolated air cells. A stress relaxation test showed that the shortening replacement with oleogels produced muffins with a firmer and springier texture. Based on fatty acid compositions, the ratio of saturated to unsaturated fatty acids was significantly reduced from 2.81 to 0.41. Use of the oleogels as a shortening replacer at a ratio of 1:3 by weight was effective in producing muffins with comparable quality attributes to the control with shortening. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Shortening of primary operators in N-extended $SCFT_{4}$ and harmonic-superspace analyticity

CERN Document Server

Andrianopoli, L.; Sokatchev, E.; Zupnik, B.

1999-01-01

We present the analysis of all possible shortenings which occur for composite gauge invariant conformal primary superfields in SU(2,2/N) invariant gauge theories. These primaries have top-spin range N/2 \\leq J_{max} < N with J_{max} = J_1 + J_2, (J_1,J_2) being the SL(2,C) quantum numbers of the highest spin component of the superfield. In Harmonic superspace, analytic and chiral superfields give J_{max}= N/2 series while intermediate shortenings correspond to fusion of chiral with analytic in N=2, or analytic with different analytic structures in N=3,4. In the AdS/CFT language shortenings of UIR's correspond to all possible BPS conditions on bulk states. An application of this analysis to multitrace operators, corresponding to multiparticle supergravity states, is spelled out.

Field monitoring of column shortenings in a high-rise building during construction.

Science.gov (United States)

Choi, Se Woon; Kim, Yousok; Kim, Jong Moon; Park, Hyo Seon

2013-10-24

The automatic monitoring of shortenings of vertical members in high-rise buildings under construction is a challenging issue in the high-rise building construction field. In this study, a practical system for monitoring column shortening in a high-rise building under construction is presented. The proposed monitoring system comprises the following components: (1) a wireless sensing system and (2) the corresponding monitoring software. The wireless sensing system comprises the sensors and energy-efficient wireless sensing units (sensor nodes, master nodes, and repeater nodes), which automate the processes for measuring the strains of vertical members and transmitting the measured data to the remote server. The monitoring software enables construction administrators to monitor real-time data collected by the server via an Internet connection. The proposed monitoring system is applied to actual 66-floor and 72-floor high-rise buildings under construction. The system enables automatic and real-time measurements of the shortening of vertical members, which can result in more precise construction.

Telomere shortening reduces Alzheimer's disease amyloid pathology in mice

NARCIS (Netherlands)

Rolyan, Harshvardhan; Scheffold, Annika; Heinrich, Annette; Begus-Nahrmann, Yvonne; Langkopf, Britta Heike; Hoelter, Sabine M.; Vogt-Weisenhorn, Daniela M.; Liss, Birgit; Wurst, Wolfgang; Lie, Dieter Chichung; Thal, Dietmar Rudolf; Biber, Knut; Rudolph, Karl Lenhard

Alzheimer's disease is a neurodegenerative disorder of the elderly and advancing age is the major risk factor for Alzheimer's disease development. Telomere shortening represents one of the molecular causes of ageing that limits the proliferative capacity of cells, including neural stem cells.

Discovery of VU6005649, a CNS Penetrant mGlu7/8 Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines.

Science.gov (United States)

Abe, Masahito; Seto, Mabel; Gogliotti, Rocco G; Loch, Matthew T; Bollinger, Katrina A; Chang, Sichen; Engelberg, Eileen M; Luscombe, Vincent B; Harp, Joel M; Bubser, Michael; Engers, Darren W; Jones, Carrie K; Rodriguez, Alice L; Blobaum, Anna L; Conn, P Jeffrey; Niswender, Colleen M; Lindsley, Craig W

2017-10-12

Herein, we report the structure-activity relationships within a series of mGlu 7 PAMs based on a pyrazolo[1,5- a ]pyrimidine core with excellent CNS penetration ( K p s > 1 and K p,uu s > 1). Analogues in this series proved to display a range of Group III mGlu receptor selectivity, but VU6005649 emerged as the first dual mGlu 7/8 PAM, filling a void in the Group III mGlu receptor PAM toolbox and demonstrating in vivo efficacy in a mouse contextual fear conditioning model.

[Effects of removable partial dentures on the quality of life in people with shortened dental arches].

Science.gov (United States)

Armellini, D B; Heydecke, G; Witter, D J; Creugers, N H J

2009-12-01

In order to assess the enhanced value of removable partial dentures on the quality of life, patients at 2 university clinics were screened for the presence of complete or shortened dental arches. Those selected were assigned to 1 of 5 subgroups: 1) a shortened dental arch with all frontal teeth, 2) a shortened dental arch with one or more frontal diastemas, 3) a shortened dental arch with all frontal teeth, restored by a removable partial denture, 4) a shortened dental arch and several diastemas, restored by a removable partial denture, 5) a complete dental arch. The participants completed the Oral Health Impact Profile (OHIP-49) and the Short Form Health Survey (SF-36). Clinical data recorded were: whether any teeth were missing and if so which, whether or not these had been replaced by a removable partial denture, and the number of occluding pairs of (pre)molars. The results revealed that a shortenend dental arch has a certain impact on the quality of life. However, the participants only experienced benefits from a removable partial denture if the denture also replaced frontal teeth.

Gastric wall shortening in early gastric cancer: upper gastrointestinal series and pathologic correlation

International Nuclear Information System (INIS)

Kim, In Jae; Choi, Chul Soon; Kim, Eun Ah; Kim, Kyu Sun; Yun, Ku Sub; Kim, Ho Chul; Bae, Sang Hun; Kang, Gu; Shin, Hyung Sik

1995-01-01

To investigate the causes of gastric wall shortening in early gastric cancer, upper gastrointestinal study was correlated with pathologic findings. We evaluated 41 cases (M:F = 1.7:1, average age = 49) of early gastric cancer, retrospectively. The gastric wall shortening were classified as Grade I; none, Grade II; intermediate, and Grade III; prominent. Pathologic findings such as size of lesions, depth of tumor invasion, degree of the submucosal fibrosis, degree of thickness of the submucosa and muscularis propria, and morphologic patterns of lesions including conversing mucosal folds were correlated with the degree of gastric wall shortening on upper gastrointestinal series. Submucosal fibrosis was present in 4 cases in Grade I (n = 21), 4 cases in Grade II (n = 6) and 8 cases in Grade III (n = 10). Positive conversing mucosal folds were seen in 5 cases in Grade I (n = 17), 0 case in Grade II (n = 2) and 9 cases in Grade III (n = 9). Gastric wall shortening was significantly associated with submucosal fibrosis and conversing mucosal folds of early gastric cancer. (ρ = 0.0001, and ρ = 0.02, respectively) Upper gastrointestinal finding of gastric wall protrusion in patients with early gastric cancer should not misinterprete as advanced gastric cancer since the finding could be a result of submucosal fibrosis

Apmierinātības ar dzīvi saistība ar laika perspektīvu

OpenAIRE

Selga, Toms

2013-01-01

Pētījuma mērķis ir noskaidrot vai pastāv saistības starp apmierinātību ar dzīvi un laika perspektīvu. Tika sagaidīts, ka indivīdiem, kam izteiktākas pozitīvās pagātnes un tagadnes hedoniskā laika uztvere, apmierinātības ar dzīvi rezultāti būs augstāki, bet indivīdiem ar negatīvās pagātnes uztveri apmierinātības ar dzīvi rādītāji būs zemāki (Zhang & Howell, 2011). Lai to noskaidrotu, tika izmantota apmierinātības ar dzīvi aptauja (Satisfaction With Life Scale, SWLS, Diener, Emmons, Larsen,...

Knowledge and attitudes of dentists toward shortened dental arch ...

African Journals Online (AJOL)

Objective: The aim of this study was to assess and compare the knowledge and attitudes of dentists toward shortened dental arch (SDA) therapy in Saudi Arabia. Materials and Methods: In this cross‑sectional study, self‑designed‑structured questionnaires were distributed among specialists (SP), residents (RES), and ...

Graphene oxide-loaded shortening as an environmentally friendly heat transfer fluid with high thermal conductivity

Directory of Open Access Journals (Sweden)

Vongsetskul Thammasit

2017-01-01

Full Text Available Graphene oxide-loaded shortening (GOS, an environmentally friendly heat transfer fluid with high thermal conductivity, was successfully prepared by mixing graphene oxide (GO with a shortening. Scanning electron microscopy revealed that GO particles, prepared by the modified Hummer’s method, dispersed well in the shortening. In addition, the latent heat of GOS decreased while their viscosity and thermal conductivity increased with increasing the amount of loaded GO. The thermal conductivity of the GOS with 4% GO was higher than that of pure shortening of ca. three times, from 0.1751 to 0.6022 W/mK, and increased with increasing temperature. The GOS started to be degraded at ca. 360°C. After being heated and cooled at 100°C for 100 cycles, its viscosity slightly decreased and no chemical degradation was observed. Therefore, the prepared GOS is potentially used as environmentally friendly heat transfer fluid at high temperature.

Measurement of clavicular length and shortening after a midshaft clavicular fracture: Spatial digitization versus planar roentgen photogrammetry.

Science.gov (United States)

Stegeman, Sylvia A; de Witte, Pieter Bas; Boonstra, Sjoerd; de Groot, Jurriaan H; Nagels, Jochem; Krijnen, Pieta; Schipper, Inger B

2016-08-01

Clavicular shortening after fracture is deemed prognostic for clinical outcome and is therefore generally assessed on radiographs. It is used for clinical decision making regarding operative or non-operative treatment in the first 2weeks after trauma, although the reliability and accuracy of the measurements are unclear. This study aimed to assess the reliability of roentgen photogrammetry (2D) of clavicular length and shortening, and to compare these with 3D-spatial digitization measurements, obtained with an electromagnetic recording system (Flock of Birds). Thirty-two participants with a consolidated non-operatively treated two or multi-fragmented dislocated midshaft clavicular fracture were analysed. Two observers measured clavicular lengths and absolute and proportional clavicular shortening on radiographs taken before and after fracture consolidation. The clavicular lengths were also measured with spatial digitization. Inter-observer agreement on the radiographic measurements was assessed using the Intraclass Correlation Coefficient (ICC). Agreement between the radiographic and spatial digitization measurements was assessed using a Bland-Altman plot. The inter-observer agreement on clavicular length, and absolute and proportional shortening on trauma radiographs was almost perfect (ICC>0.90), but moderate for absolute shortening after consolidation (ICC=0.45). The Bland-Altman plot compared measurements of length on AP panorama radiographs with spatial digitization and showed that planar roentgen photogrammetry resulted in up to 37mm longer and 34mm shorter measurements than spatial digitization. Measurements of clavicular length on radiographs are highly reliable between observers, but may not reflect the actual length and shortening of the clavicle when compared to length measurements with spatial digitization. We recommend to use proportional shortening when measuring clavicular length or shortening on radiographs for clinical decision making. Copyright �

VU6010608, a Novel mGlu7 NAM from a Series of N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides.

Science.gov (United States)

Reed, Carson W; McGowan, Kevin M; Spearing, Paul K; Stansley, Branden J; Roenfanz, Hanna F; Engers, Darren W; Rodriguez, Alice L; Engelberg, Eileen M; Luscombe, Vincent B; Loch, Matthew T; Remke, Daniel H; Rook, Jerri M; Blobaum, Anna L; Conn, P Jeffrey; Niswender, Colleen M; Lindsley, Craig W

2017-12-14

Herein, we report the structure-activity relationships within a series of mGlu 7 NAMs based on an N -(2-(1 H -1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamide core with excellent CNS penetration ( K p 1.9-5.8 and K p,uu 0.4-1.4). Analogues in this series displayed steep SAR. Of these, VU6010608 ( 11a ) emerged with robust efficacy in blocking high frequency stimulated long-term potentiation in electrophysiology studies.

Slicing up the San Francisco Bay Area: Block kinematics and fault slip rates from GPS-derived surface velocities

Science.gov (United States)

d'Alessio, M. A.; Johanson, I.A.; Burgmann, R.; Schmidt, D.A.; Murray, M.H.

2005-01-01

Observations of surface deformation allow us to determine the kinematics of faults in the San Francisco Bay Area. We present the Bay Area velocity unification (BA??VU??, "bay view"), a compilation of over 200 horizontal surface velocities computed from campaign-style and continuous Global Positioning System (GPS) observations from 1993 to 2003. We interpret this interseismic velocity field using a three-dimensional block model to determine the relative contributions of block motion, elastic strain accumulation, and shallow aseismic creep. The total relative motion between the Pacific plate and the rigid Sierra Nevada/Great Valley (SNGV) microplate is 37.9 ?? 0.6 mm yr-1 directed toward N30.4??W ?? 0.8?? at San Francisco (??2??). Fault slip rates from our preferred model are typically within the error bounds of geologic estimates but provide a better fit to geodetic data (notable right-lateral slip rates in mm yr-1: San Gregorio fault, 2.4 ?? 1.0; West Napa fault, 4.0 ?? 3.0; zone of faulting along the eastern margin of the Coast Range, 5.4 ?? 1.0; and Mount Diablo thrust, 3.9 ?? 1.0 of reverse slip and 4.0 ?? 0.2 of right-lateral strike slip). Slip on the northern Calaveras is partitioned between both the West Napa and Concord/ Green Valley fault systems. The total convergence across the Bay Area is negligible. Poles of rotation for Bay Area blocks progress systematically from the North America-Pacific to North America-SNGV poles. The resulting present-day relative motion cannot explain the strike of most Bay Area faults, but fault strike does loosely correlate with inferred plate motions at the time each fault initiated. Copyright 2005 by the American Geophysical Union.

Device and method for shortening reactor process tubes

Science.gov (United States)

Frantz, Charles E.; Alexander, William K.; Lander, Walter E. B.

1980-01-01

This disclosure describes a device and method for in situ shortening of nuclear reactor zirconium alloy process tubes which have grown as a result of radiation exposure. An upsetting technique is utilized which involves inductively heating a short band of a process tube with simultaneous application of an axial load sufficient to cause upsetting with an attendant decrease in length of the process tube.

The Shortened Raven Standard Progressive Matrices: Item Response Theory-Based Psychometric Analyses and Normative Data

Science.gov (United States)

Van der Elst, Wim; Ouwehand, Carolijn; van Rijn, Peter; Lee, Nikki; Van Boxtel, Martin; Jolles, Jelle

2013-01-01

The purpose of the present study was to evaluate the psychometric properties of a shortened version of the Raven Standard Progressive Matrices (SPM) under an item response theory framework (the one- and two-parameter logistic models). The shortened Raven SPM was administered to N = 453 cognitively healthy adults aged between 24 and 83 years. The…

A Comparative Field Monitoring of Column Shortenings in Tall Buildings Using Wireless and Wired Sensor Network Systems

Directory of Open Access Journals (Sweden)

Sungho Lee

2016-01-01

Full Text Available A comparative field measurement for column shortening of tall buildings is presented in this study, with a focus on the reliability and stability of a wireless sensor network. A wireless sensor network was used for monitoring the column shortenings of a 58-story building under construction. The wireless sensor network, which was composed of sensor and master nodes, employed the ultra-high-frequency band and CDMA communication methods. To evaluate the reliability and stability of the wireless sensor network system, the column shortenings were also measured using a conventional wired monitoring system. Two vibration wire gauges were installed in each of the selected 7 columns and 3 walls. Measurements for selected columns and walls were collected for 270 days after casting of the concrete. The results measured by the wireless sensor network were compared with the results of the conventional method. The strains and column shortenings measured using both methods showed good agreement for all members. It was verified that the column shortenings of tall buildings could be monitored using the wireless sensor network system with its reliability and stability.

Shortened protocol in practical [11C]SA4503-PET studies for sigma1 receptor quantification

International Nuclear Information System (INIS)

Sakata, Muneyuki; Kimura, Yuichi; Ishikawa, Masatomo; Oda, Keiichi; Ishii, Kenji; Ishiwata, Kiichi; Naganawa, Mika; Hashimoto, Kenji; Chihara, Kunihiro

2008-01-01

In practical positron emission tomography (PET) diagnosis, a shortened protocol is preferred for patients with brain disorders. In this study, the applicability of a shortened protocol as an alternative to the 90-min PET scan with [ 11 C]SA4503 for quantitative sigma 1 receptor measurement was investigated. Tissue time-activity curves of 288 regions of interest in the brain from 32 [ 11 C]SA4503-PET scans of 16 healthy subjects prior to and following administration of a selective serotonin reuptake inhibitor (fluvoxamine or paroxetine) were applied to two algorithms of quantitative analysis; binding potential (BP) was derived from compartmental analysis based on nonlinear estimation, and total distribution volume (tDV) was derived from Logan plot analysis. As a result, although both BP and tDV tended to be underestimated by the shortened method, the estimates from the shortened protocol had good linear relationships with those of the full-length protocol. In conclusion, if approximately 10% differences in the estimated results are acceptable for a specific purpose, then a 60-min measurement protocol is capable of providing reliable results. (author)

Damage sensing ability of polymer nanocomposites filled with long, shortened and damaged carbon nanotubes

OpenAIRE

Inam, Fawad; Okolo, Chichi; Vo, Thuc

2016-01-01

Carbon nanotubes (CNTs) were aggressively tip-ultrasonicated to produce shortened and damaged carbon nanotubes. High-resolution scanning electron microscopic analysis was performed to measure the dimensions of CNTs. Thermo-gravimetric analysis (TGA) was used to evaluate the damage in the sonicated CNTs. Shortened CNTs, in their pristine form (undamaged), were used for comparison with damaged CNTs. Nanocomposite bars, containing CNTs, were indented using Vickers hardness testing machine to pro...

On protecting the planet against cosmic attack: Ultrafast real-time estimate of the asteroid's radial velocity

Science.gov (United States)

Zakharchenko, V. D.; Kovalenko, I. G.

2014-05-01

A new method for the line-of-sight velocity estimation of a high-speed near-Earth object (asteroid, meteorite) is suggested. The method is based on the use of fractional, one-half order derivative of a Doppler signal. The algorithm suggested is much simpler and more economical than the classical one, and it appears preferable for use in orbital weapon systems of threat response. Application of fractional differentiation to quick evaluation of mean frequency location of the reflected Doppler signal is justified. The method allows an assessment of the mean frequency in the time domain without spectral analysis. An algorithm structure for the real-time estimation is presented. The velocity resolution estimates are made for typical asteroids in the X-band. It is shown that the wait time can be shortened by orders of magnitude compared with similar value in the case of a standard spectral processing.

Protein degradation and post-deboning tenderization in broiler breast meat with different degrees of muscle shortening

Science.gov (United States)

Deboning broiler breast fillets prior to rigor mortis negatively influences tenderness due to sarcomere shortening. The effects of sarcomere shortening on muscle protein degradation and breast meat tenderization during post-deboning aging are not well understood. The objective of this study was to m...

Does Shortened Application Time Affect Long-Term Bond Strength of Universal Adhesives to Dentin?

Science.gov (United States)

Saikaew, P; Matsumoto, M; Chowdhury, Afma; Carvalho, R M; Sano, H

2018-04-09

This study evaluated the effect of shortened application time on long-term bond strength with universal adhesives. Three universal adhesives were used: Clearfil Universal Bond (CU, Kuraray Noritake Dental Inc, Tokyo, Japan), Scotchbond Universal Adhesive (SB, 3M ESPE, St Paul, MN, USA) or G-Premio Bond (GP, GC Corp, Tokyo, Japan). Sixty molars were cut to expose midcoronal dentin and prepared with a regular diamond bur. Each adhesive was applied either according to the manufacturer's instruction or with shortened time. Specimens were stored in distilled water at 37°C for 24 hours and then cut into resin-dentin sticks. Microtensile bond strength (μTBS) was tested after either 24 hours or 1 year of water storage. Data were analyzed by the three-way ANOVA and Duncan tests ( α=0.05). Fracture modes were analyzed under a scanning electron microscope (SEM). One dentin stick per group was selected after fracture mode analysis and further observed using transmission electron microscopy (TEM). Six additional dentin discs were prepared and conditioned with each adhesive under the different application time to observe the adhesive-smear layer interaction by SEM. Shortened application time affected the μTBS ( puniversal adhesives to bur-cut dentin. The performance of universal adhesives can be compromised when applied using a shortened application time.

The psychometric properties of a shortened corporate entrepreneurship assessment instrument

Directory of Open Access Journals (Sweden)

Renier Steyn

2017-08-01

Aim: The aim of this research was to evaluate the psychometric properties of a measure of entrepreneurial climate. Entrepreneurial climate was measured using a shortened version of the Hornsby, Kuratko and Zahra (2002 instrument, called the Corporate Entrepreneurship Assessment Instrument (CEAI. Making information on the psychometric properties of the instrument available directly relates to its utility. Setting: The setting was medium to large South African companies. A random sample of employees was drawn from 53 selected companies across South Africa, with 60 respondents per company (N = 3 180. Methods: A cross-sectional survey design was used. Several instruments were administered, including the shortened version of the CEAI. Cronbach’s alpha was used to test for reliability and several methods were used to test for validity. Correlation analysis was used to test for concurrent validity, convergent validity and divergent validity. Principle component factor analysis was used to test for factorial validity and a t-test to test for known-group validity. Results: The results showed that the reliability for the total score of the shortened version of the CEAI was acceptable at 0.758. The results also showed some evidence of concurrent validity, as well as homogeneity among the items. With regard to factorial validity, all items loaded in accordance with the subscales of the instrument. The measure was able to distinguish, as expected, between government organisations and private business entities, suggesting known-group validity. Convergent validity and divergent validity were also assessed. Interesting to note was that entrepreneurship climate correlates more with general employee attitude (e.g. employee engagement; R= 0.420, p < 0.001 and organisational commitment, R = 0.331, p < 0.001 than with self-reported innovation (R = 0.277, p < 0.001 and R = 0.267, p < 0.001. Contribution: This paper not only provided information on the reliability

One-stage lengthening using a locked nailing technique for distal femoral shaft nonunions associated with shortening.

Science.gov (United States)

Wu, Chi-Chuan; Lee, Zhon-Liau

2004-02-01

To assess the effectiveness of a one-stage lengthening using a locked nail technique for the treatment of distal femoral shaft nonunions associated with shortening. Retrospective. University hospital. During a 6-year period, 36 distal femoral shaft nonunions associated with shortening (>1.5 cm) were treated by the one-stage lengthening technique. Indications for this technique were distal femoral shaft aseptic or quiescent infected nonunions, 1.5-5 cm shortening, and a fracture level suitable for the insertion of two distal locked screws. The surgical technique involved skeletal traction using the femoral condyle, local débridement, lengthening by lengthening was 2.5 cm (range 1.5-3.5 cm). One-stage lengthening using the locked nailing technique to treat distal femoral shaft nonunions associated with shortening can achieve a high success rate and low complication rate. The key to successful treatment is the patient's complete cooperation with strictly protected weight bearing until the fracture has healed.

Methods for Shortening and Extending the Carbon Chain in Carbohydrates

DEFF Research Database (Denmark)

Monrad, Rune Nygaard

2008-01-01

in this thesis focuses on the development and application of transition metal mediated methods for shortening and extending the carbon chain in carbohydrates thereby providing access to lower and higher sugars.A new catalytic procedure for shortening unprotected sugars by one carbon atom has been developed....... The procedure has been employed as the key step in a short five-step synthesis of the unnatural sugar L-threose in 74% overall yield from D-glucose. A zinc-mediated one-pot fragmentation-allylation reaction has been used to elongate D-glucose and D-ribose by three carbon atoms thereby producing carbohydrate......-derived α,ω-dienes, which have been converted into the natural products calystegine A3 and gabosine A. The glycosidase inhibitor calystegine A3 was produced by two similar routes from commercially available methyl α-D-glucopyranoside in 13 and 14 steps with 8.3 and 5.3% overall yield, respectively...

Long-axis fractional shortening and mitral annulus motion in dogs

Directory of Open Access Journals (Sweden)

Marlos Gonçalves Sousa

2016-10-01

Full Text Available Ventricular systolic dynamics involves the contraction of transverse and longitudinal myocardial fibers. Unfortunately, only the activity of the transverse myocardial fibers is foreseen by the standard systolic echocardiographic parameters. Although strain and strain rate have been used to assess the radial, circumferential and longitudinal planes of cardiac contraction, such analysis requires advanced equipment which is not always available in veterinary medicine. On the contrary, some unusual parameters may be recorded via standard methodology, allowing for the specific evaluation of left ventricular longitudinal contractility. In this study, the longitudinal contractile activity was evaluated using the long-axis fractional shortening and the mitral annulus motion, which were compared with several standard echocardiographic parameters in 14 beagles, including seven with asymptomatic mitral valve disease. The long-axis fractional shortening was positively correlated with both the mitral annulus motion and the end-diastolic left-ventricular diameter. Also, a significant correlation was found to exist between the mitral annulus motion and the left-ventricular end-diastolic diameter, which is likely supportive of its preload dependency. Even though no difference was documented in either mitral annulus motion or long-axis fractional shortening between healthy dogs and dogs with mitral valve disease, the latter only included animals with minimal cardiac remodeling, with no overt compromise of systolic function. Since it is possible to obtain these two parameters with any echocardiographic equipment, their inclusion in the routine exam would probably add information regarding the activity of the longitudinal myocardial fibers, whose functional deterioration supposedly occurs prior to the impairment of transverse fibers.

Telomere shortening in the colonic mucosa of patients with ulcerative colitis.

Science.gov (United States)

Kinouchi, Y; Hiwatashi, N; Chida, M; Nagashima, F; Takagi, S; Maekawa, H; Toyota, T

1998-06-01

Telomere length in human somatic cells gradually decreases with the number of cell divisions and is regarded as a marker of somatic cell turnover. Mucosal cells of the affected colon show rapid turnover in individuals with active ulcerative colitis (UC). Telomere length was determined by Southern blot analysis of terminal restriction fragments (TRFs) from the colonic mucosa of 17 patients with UC in remission, two of whom showed dysplasia, and 17 control subjects without colitis. For each individual, mean TRF length was compared between rectal mucosa and unaffected cecal mucosa. The mean TRF length of the rectal mucosa was significantly less than that of cecal mucosa in UC patients (7.87 +/- 0.36kb versus 8.77 +/- 0.21 kb; P = 0.0015, Wilcoxon signed rank test), whereas no significant difference was detected in the control subjects. The extent of telomere shortening was 10.6 +/- 3.35% in UC patients, compared with 0.8 +/- 0.64% in noncolitis controls (P = 0.0024, Mann-Whitney U-test). Four UC patients, two of whom had dysplasia, showed telomere shortening of more than 20% in the rectal mucosa. These observations suggest that telomere shortening in the colonic mucosa of individuals with UC may represent the history of mucosal inflammation during disease of long duration, and that it may contribute to aneuploidy in UC.

Effects of neuromuscular joint facilitation on baseball pitching velocity and electromechanical reaction times of the teres major of young amateur baseball players.

Science.gov (United States)

Wu, Peng; Huo, Ming; Maruyama, Hitoshi

2013-11-01

[Purpose] The aim of this study was to investigate the changes of baseball pitching velocity and electromechanical reaction times (EMG-RT) of the teres major of young amateur baseball players after neuromuscular joint facilitation (NJF) treatment. [Subjects] The subjects were 18 healthy males who were divided into two groups: a NJF group and a control group. The NJF group consisted of 10 subjects, and the control group consisted of 8 subjects. [Methods] Participants in the NJF group received NJF treatment. The baseball pitching velocity, the EMG-RT, the premotor time (PMT), and the motor time (MT) during shoulder internal rotation movement were measured before and after 8 weeks of exercise. [Results] There were no significant differences among the results of the control group. In the NJF group, there were significant differences in baseball pitching velocity, EMG-RT and MT after NJF treatment. [Conclusion] NJF intervention shortens not only EMG-RT but also MT, which implies that NJF is effective for motor processes. Since the baseball pitching velocity increased, NJF may be recommended for the improvement of the performance of baseball players.

Telomere shortening in hematopoietic stem cell transplantation: a potential mechanism for late graft failure?

Science.gov (United States)

Awaya, Norihiro; Baerlocher, Gabriela M; Manley, Thomas J; Sanders, Jean E; Mielcarek, Marco; Torok-Storb, Beverly; Lansdorp, Peter M

2002-01-01

Telomeres serve to maintain the structural integrity of chromosomes, yet each somatic cell division is associated with a decrease in telomere length. The cumulative decrease in telomere length can impose an upper limit for the number of cell divisions that can occur before a cell senesces. When studied in vitro with fibroblasts, this limit is referred to as the Hayflick limit and usually occurs after 40 to 80 cell doublings. In theory, a similar replicative potential in a hematopoietic stem cell could support hematopoiesis in a person for more than 100 years. However, stem cells differentiate, and the telomere length differs among chromosomes within a single cell, among cell types, and among age-matched individuals. This variation in telomere length raises the possibility that long-term hematopoiesis by transplanted stem cells could, depending on the telomere length of the engrafted stem cell and the proliferative demand to which it is subjected, reach a Hayflick limit during the life span of the patient. Although significant shortening of telomeres is reported to occur within the first year posttransplantation, as yet no evidence has indicated that this shortening is associated with marrow function. In this review, we summarize reports on telomere shortening in stem cell transplantation recipients and report 2 cases in which graft failure is associated with significant telomere shortening.

Matrix effects on the crystallization behaviour of butter and roll-in shortening in laminated bakery products.

Science.gov (United States)

Mattice, Kristin D; Marangoni, Alejandro G

2017-06-01

Two hydrogenated roll-in shortenings (A & B), one non-hydrogenated roll-in shortening and butter were used to prepare croissants. The impact of the laminated dough matrix on fat crystallization was then investigated using powder X-ray diffraction (XRD), pulsed nuclear magnetic resonance (p-NMR) and differential scanning calorimetry (DSC). The fat contained within a croissant matrix has never before been analyzed using these techniques. In each case, XRD revealed that the polymorphism of a roll-in fat will be different when baked within the dough matrix than when simply heated and cooled on its own. Both hydrogenated roll-in shortenings and butter experienced only minor changes, largely retaining their β' polymorphs, but the non-hydrogenated shortening experienced significant conversion from β' to the β form. However, this conversion did not take place immediately upon cooling, but after approximately 24h of storage time. The fat contained within the croissants exhibited a significantly lower SFC than the same fats in bulk. Further, DSC results demonstrated that a greater temperature was required to completely melt all of the fat in a croissant than the same fat in bulk, observed visually as broader peaks in the melting endotherms. Analysis of croissant firmness over storage time, measured as the maximum force required to cut a croissant was used as an indication of potential sensory consequences. Results suggested that only croissants prepared with non-hydrogenated shortening experienced significant changes in firmness over one week of storage. These results indicate that there is an interaction between the shortenings and the ingredients of the croissant matrix, and given the differences observed between roll-in fats used, the extent of interaction is potentially influenced by the composition of the roll-in fat itself. Copyright © 2017 Elsevier Ltd. All rights reserved.

Challenges in Shortening New Product Introduction in the Pharmaceutical Industry

DEFF Research Database (Denmark)

Hansen, Klaus Reinholdt Nyhuus; Grunow, Martin

2010-01-01

Drug developing companies are forced to utilize the effective protection of the patent by focusing on shortening the new product introduction [NPI] process measured as Time-to-Market [TTM]. Here the NPI process is considered and the trade-offs, which have to be address in the future are identifie...

Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice.

Directory of Open Access Journals (Sweden)

Aparna Raval

Full Text Available Telomere shortening is common in bone marrow failure syndromes such as dyskeratosis congenita (DC, aplastic anemia (AA and myelodysplastic syndromes (MDS. However, improved knowledge of the lineage-specific consequences of telomere erosion and restoration of telomere length in hematopoietic progenitors is required to advance therapeutic approaches. We have employed a reversible murine model of telomerase deficiency to compare the dependence of erythroid and myeloid lineage differentiation on telomerase activity. Fifth generation Tert-/- (G5 Tert-/- mice with shortened telomeres have significant anemia, decreased erythroblasts and reduced hematopoietic stem cell (HSC populations associated with neutrophilia and increased myelopoiesis. Intracellular multiparameter analysis by mass cytometry showed significantly reduced cell proliferation and increased sensitivity to activation of DNA damage checkpoints in erythroid progenitors and in erythroid-biased CD150hi HSC, but not in myeloid progenitors. Strikingly, Cre-inducible reactivation of telomerase activity restored hematopoietic stem and progenitor cell (HSPC proliferation, normalized the DNA damage response, and improved red cell production and hemoglobin levels. These data establish a direct link between the loss of TERT activity, telomere shortening and defective erythropoiesis and suggest that novel strategies to restore telomerase function may have an important role in the treatment of the resulting anemia.

Effects of resistance training using known vs unknown loads on eccentric-phase adaptations and concentric velocity.

Science.gov (United States)

Hernández-Davó, J L; Sabido, R; Behm, D G; Blazevich, A J

2018-02-01

The aims of this study were to compare both eccentric- and concentric-phase adaptations in highly trained handball players to 4 weeks of twice-weekly rebound bench press throw training with varying loads (30%, 50% and 70% of one-repetition maximum [1-RM]) using either known (KL) or unknown (UL) loads and to examine the relationship between changes in eccentric- and concentric-phase performance. Twenty-eight junior team handball players were divided into two experimental groups (KL or UL) and a control group. KL subjects were told the load prior each repetition, while UL were blinded. For each repetition, the load was dropped and then a rebound bench press at maximum velocity was immediately performed. Both concentric and eccentric velocity as well as eccentric kinetic energy and musculo-articular stiffness prior to the eccentric-concentric transition were measured. Results showed similar increases in both eccentric velocity and kinetic energy under the 30% 1-RM but greater improvements under 50% and 70% 1-RM loads for UL than KL. UL increased stiffness under all loads (with greater magnitude of changes). KL improved concentric velocity only under the 30% 1-RM load while UL also improved under 50% and 70% 1-RM loads. Improvements in concentric movement velocity were moderately explained by changes in eccentric velocity (R 2 =.23-.62). Thus, UL led to greater improvements in concentric velocity, and the improvement is potentially explained by increases in the speed (as well as stiffness and kinetic energy) of the eccentric phase. Unknown load training appears to have significant practical use for the improvement of multijoint stretch-shortening cycle movements. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Effects of post mortem temperature on rigor tension, shortening and ...

African Journals Online (AJOL)

Fully developed rigor mortis in muscle is characterised by maximum loss of extensibility. The course of post mortem changes in ostrich muscle was studied by following isometric tension, shortening and change in pH during the first 24 h post mortem within muscle strips from the muscularis gastrocnemius, pars interna at ...

Mini-open spinal column shortening for the treatment of adult tethered cord syndrome.

Science.gov (United States)

Safaee, Michael M; Winkler, Ethan A; Chou, Dean

2017-10-01

Tethered cord syndrome (TCS) is a challenging entity characterized by adhesions at the caudal spinal cord that prevent upward movement during growth and result in stretching of the cord with a concomitant constellation of neurologic symptoms. Although growth in height stops in adulthood, some patients still develop progressive symptoms; many underwent detethering as a child or adolescent, resulting in significant scar tissue and re-tethering. Recent strategies have focused on spinal column shortening to reduce tension on the spinal cord without exposing the previous de-tethering site. Mini-open and minimally invasive approaches avoid the large dissection and exposure associated with traditional approaches and are associated with reduced blood loss, shorter hospital stay, and similar outcomes when compared to conventional open approaches. We describe a technique for mini-open spinal column shortening. Using intraoperative navigation pedicle screws were placed at T10, T11, L1, and L2. A mini-open 3-column "egg shell" decancellation osteotomy of T12 was performed through a transpedicular approach with preservation of the superior and inferior endplates. This procedure was performed on a 28year old male with recurrent TCS and neurogenic bladder. Postoperative imaging showed a reduction in spinal column length of 1.5cm and evidence of decreased tension on the spinal cord. At last follow-up he was recovering well with improved urinary function. Spinal column shortening for adult TCS can be safely achieved through a mini-open approach. Future studies should compare the efficacy of this technique to both traditional de-tethering and open spinal column shortening. Copyright © 2017 Elsevier Ltd. All rights reserved.

Operative shortening of the sling as a second-line treatment after TVT failure

Science.gov (United States)

Matuszewski, Marcin; Michajłowski, Jerzy; Krajka, Kazimierz

2011-01-01

Introduction Stress urinary incontinence (SUI) is defined as an involuntary loss of urine during physical exertion, sneezing, coughing, laughing, or other activities that put pressure on the bladder. In some cases, recurrent or persistent SUI after sling operations may be caused by too loose placement of the sling. In the current study, we describe our method of shortening of the sling as a second-line treatment of tension-free vaginal tape (TVT) failure. Materials and methods Four women, aged 46-61, after initial TVT operation were treated for persistent SUI. The severity of SUI was estimated by: physical examinations, cough tests, 24-h pad tests, and King's Health Questionnaire. The shortening procedure, based on excising the fragment of tape and suturing it back, was performed in all patients. Results All cases achieved a good result, which was defined as restoration of full continence. No complications occurred. The 12-month follow-up showed no side-effects. The postoperative control tests: the cough and 24-h pad tests were negative in all women. The general health perceptions increased after the shortening procedure by a mean value 44.25%. The incontinence impact decreased by a mean value 44.6%. In all patients, role and physical limitations significantly decreased (by 88.5% and 80.5%, respectively). The negative emotions connected with SUI significantly decreased after the second procedure. Conclusions The operative shortening of the implanted sling is a simple, cheap, and effective method of second-line treatment in cases of TVT failure and may be offered to the majority of patients with insufficient urethral support after the first procedure. PMID:24578885

Decayed/missing/filled teeth and shortened dental arches in Tanzanian adults.

NARCIS (Netherlands)

Sarita, P.T.N.; Witter, D.J.; Kreulen, C.M.; Matee, M.I.N.; Hof, M.A. van 't; Creugers, N.H.J.

2004-01-01

PURPOSE: This study assessed decayed/missing/filled teeth (DMFT), presence of occlusal units, and prevalence of shortened dental arches in a Tanzanian adult population. MATERIALS AND METHODS: The dental state of samples of the Tanzanian population was studied. Oral examinations were conducted on

Mid-term clinical outcome of radial shortening for kienbock disease

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Mohammad H Ebrahimzadeh

2015-01-01

Full Text Available Background: To evaluate the intermediate-term outcomes of radius shortening as a treatment for Kienbock′s disease. Materials and Methods: In a historical cohort, 16 skeletally mature patients (9 men and 7 women with Kienbock disease, who were treated with radial shortening osteotomy between 2002 and 2012, were reviewed in our study. The mean age of our patients was 30 (range 18-43 years old. According to Litchman staging, there were 7 wrists at stage II and 9 wrists at stage III (6 at stage IIIA and 3 at stage IIIB. The data of grip strength, pain (visual analog scale (VAS score, wrist range of motion (ROM, ulnar variance (according to Palmer method, and the Lichtman stage were gathered before and after surgery. We evaluated overall wrist function using the Mayo Wrist score and disabilities of the arm shoulder and hand (DASH score before surgery and at the last follow-up. Results: The average of follow-up was 7 years (range from 5 to 9 years. Preoperative ulnar variance was -1.3 mm (range from 2.5 to 1 preoperatively. The mean postoperative ulnar variance was 1 mm positive (range from 0.5 to 1.5. The VAS pain score, the mean arc of wrist flexion and extension, and grip strength improved significantly preoperatively compared to after recovery from surgery. The Lichtman stage was unchanged in nine patients, one grade worse in six patients, and one grade better in one patient. The mean DASH and Mayo scores improved significantly postoperatively compare with preoperation. Comparing preoperative positive, neuter, and negative ulnar variance, there was no significant difference in terms of VAS, DASH, and Mayo scores as well as ROM and grip strength. Conclusion: Our study shows that radius shortening surgery improves pain and disability regardless of ulnar variance.

Development and assessment of a shortened Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-55).

Science.gov (United States)

Goodwin, Shane W; Lambrinos, Anastasia I; Ferro, Mark A; Sabaz, Mark; Speechley, Kathy N

2015-06-01

To develop and validate a shortened version of the Quality of Life in Childhood Epilepsy Questionnaire (QOLCE). A secondary aim was to compare baseline risk factors predicting health-related quality of life (HRQoL) in children newly diagnosed with epilepsy, as identified using the original and shortened version. Data came from the Health-Related Quality of Life in Children with Epilepsy Study (HERQULES, N = 373), a multicenter prospective cohort study. Principal component analysis reduced the number of items from the original QOLCE, and factor analysis was used to assess the factor structure of the shortened version. Convergent and divergent validity was assessed by correlating the Child Health Questionnaire (CHQ) with the shortened QOLCE. Multiple regression identified risk factors at diagnosis for HRQoL at 24 months. A four-factor, higher-order, 55-item solution was obtained. A total of 21 items were removed. The final model represents functioning in four dimensions of HRQoL: Cognitive, Emotional, Social, and Physical. The shortened QOLCE demonstrated acceptable fit: Bentler's Comparative Fit Index = 0.944; Tucker-Lewis Index = 0.942; root mean square approximation = 0.058 (90% CI: 0.056-0.061); weighted root mean square residuals (WRMR) = 1.582, and excellent internal consistency (α = 0.96, subscales α > 0.80). Factor loadings were good (first-order: λ = 0.66-0.93; higher-order λ = 0.66-0.85; p QOLCE scores correlated strongly with similar subscales of the Child Health Questionnaire (ρ = 0.38-0.70) while correlating weakly with dissimilar subscales (ρ = 0.30-0.31). While controlling for HRQoL at diagnosis, predictors for better HRQoL at 24 months were the following: no cognitive problems reported (p = 0.001), better family functioning (p = 0.014), fewer family demands (p = 0.008), with an interaction between baseline HRQoL and cognitive problems (p = 0.011). Results offer initial evidence regarding reliability and validity of the proposed 55-item shortened

Handgrip strength, quadriceps muscle power, and optimal shortening velocity roles in maintaining functional abilities in older adults living in a long-term care home: a 1-year follow-up study

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Kozicka I

2016-05-01

Full Text Available Izabela Kozicka, Tomasz Kostka Department of Geriatrics, Medical University of Lodz, Lodz, Poland Purpose: To assess the relative role of handgrip strength (HGS, quadriceps muscle power (Pmax, and optimal shortening velocity (υopt in maintaining functional abilities (FAs in older adults living in a long-term care home over a 1-year follow-up. Subjects and methods: Forty-one inactive older institutionalized adults aged 69.8±9.0 years participated in this study. HGS, Pmax, υopt, cognitive function using the Mini-Mental State Examination, depressive symptoms using the Geriatric Depression Scale, nutritional status using the Mini Nutritional Assessment (MNA, and physical activity (PA using the Seven-Day Physical Activity Recall Questionnaire were assessed at baseline and at 1-year follow-up. FAs were assessed with activities of daily living (ADL, instrumental ADL, and Timed Up & Go test. Results: Both at baseline and at follow-up, FAs were related to age, HGS, Pmax/kg, υopt, MNA, and PA. These associations were generally similar in both sexes. As revealed in multiple regression analysis, υopt was the strongest predictor of FA, followed by Pmax/kg, PA, and MNA. FA deteriorated after 1 year as measured by ADL and Timed Up & Go test. Pmax and υopt, but not HGS, also decreased significantly after 1 year. Nevertheless, 1-year changes in FAs were not related to changes in HGS, Pmax, υopt, or PA. Conclusion: The 1-year period of physical inactivity among older institutionalized adults was found to have a negative effect on their FAs, Pmax, and υopt. The present study demonstrates that Pmax and, especially, υopt correlated with FAs of older adults more than HGS, both at baseline and at follow-up. Despite this, 1-year natural fluctuations of PA, Pmax, and υopt are not significant enough to influence FAs in inactive institutionalized older adults. Keywords: aging, handgrip strength, institutionalization, functional status, physical activity

Differential Telomere Shortening in Blood versus Arteries in an Animal Model of Type 2 Diabetes

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Samira Tajbakhsh

2015-01-01

Full Text Available Vascular dysfunction is an early feature of diabetic vascular disease, due to increased oxidative stress and reduced nitric oxide (NO bioavailability. This can lead to endothelial cell senescence and clinical complications such as stroke. Cells can become senescent by shortened telomeres and oxidative stress is known to accelerate telomere attrition. Sirtuin 1 (SIRT1 has been linked to vascular health by upregulating endothelial nitric oxide synthase (eNOS, suppressing oxidative stress, and attenuating telomere shortening. Accelerated leukocyte telomere attrition appears to be a feature of clinical type 2 diabetes (T2D and therefore the telomere system may be a potential therapeutic target in preventing vascular complications of T2D. However the effect of T2D on vascular telomere length is currently unknown. We hypothesized that T2D gives rise to shortened leukocyte and vascular telomeres alongside reduced vascular SIRT1 expression and increased oxidative stress. Accelerated telomere attrition was observed in circulating leukocytes, but not arteries, in T2D compared to control rats. T2D rats had blunted arterial SIRT1 and eNOS protein expression levels which were associated with reduced antioxidant defense capacity. Our findings suggest that hyperglycemia and a deficit in vascular SIRT1 per se are not sufficient to prematurely shorten vascular telomeres.

Interlayer material transport during layer-normal shortening. Part I. The model

NARCIS (Netherlands)

Molen, I. van der

1985-01-01

To analyse mass-transfer during deformation, the case is considered of a multilayer experiencing a layer-normal shortening that is volume constant on the scale of many layers. Strain rate is homogeneously distributed on the layer-scale if diffusion is absent; when transport of matter between the

Multiple congenital brachymetatarsia. A one-stage combined shortening and lengthening procedure without iliac bone graft.

Science.gov (United States)

Kim, J S; Baek, G H; Chung, M S; Yoon, P W

2004-09-01

We performed nine metatarsal and three proximal phalangeal lengthenings in five patients with congenital brachymetatarsia of the first and one or two other metatarsal bones, by a one-stage combined shortening and lengthening procedure using intercalcary autogenous bone grafts from adjacent shortened metatarsal bones. Instead of the isolated lengthening of the first and the other metatarsal bones, we shortened the adjacent normal metatarsal and used the excised bone to lengthen the short toes, except for the great toe, to restore the normal parabola. One skin incision was used. All the operations were performed bilaterally and the patients were followed up for a mean period of 69.5 months (29 to 107). They all regained a nearly normal parabola and were satisfied with the cosmetic results. Our technique is straightforward and produces good cosmetic results. Satisfactory, bony union is achieved, morbidity is low, and no additional surgery is required for the removal of metal implants.

Quantum gravity removes classical singularities and shortens the life of black holes

International Nuclear Information System (INIS)

Frolov, V.P.; Vilkovisky, G.A.

1979-07-01

The problem of the gravitational collapse is considered in the framework of the quantum gravity effective action. It is shown that quantum gravity removes classical singularity and possibly shortens the lifetime of the black hole. (author)

Limb shortening osteotomy in a patient with achondroplasia and leg length difference after total hip arthroplasty

Directory of Open Access Journals (Sweden)

Christian L. Galata

2013-07-01

Full Text Available Introduction: Achondroplasia is the most common reason for disproportionate short stature. Normally, orthopedic limb lengthening procedures must be discussed in the course of this genetic disorder and have been successful in numerous achondroplastic patients in the past. In some cases, the disease may lead to leg length differences with need for surgical correction. Case Report: We report a case of achondroplastic dysplastic coxarthrosis with symptomatic leg length difference after bilateral total hip arthroplasty in a 52-year-old female patient, in which a distal femoral shortening osteotomy was successfully performed. Conclusion: Femoral shortening osteotomy is very uncommon in patients with achondroplasia. We conclude, however, that in rare cases it can be indicated and provide the advantage of shorter operation time, less perioperative complications and faster recovery compared to leg lengthening procedures. Keywords: Achondroplasia, dysplastic coxarthrosis, limb shortening, distal femur osteotomy.

Clinical efficacy comparison of flabby skin excision combined orbicularis oculi muscle shortening surgery in patients with senile entropion

Directory of Open Access Journals (Sweden)

Qing-Liang Xu

2015-07-01

Full Text Available AIM: To observe the clinical effect of slack skin excision combined with orbicularis oculi muscle shortening and orbicularis muscle shortening in the treatment of elderly patients with lower eyelid entropion, and provide the reference for the clinical treatment.METHODS: Eighty-two(126 eyesclinical diagnosis's elderly patients with lower eyelid entropion were collected from our department, then randomly divided into excised relaxing skin and orbicularis oculi muscle shortening treatment group and the orbicularis muscle shortening treatment group.The general data of the two groups, long term curative effect and short-term curative effect were compared. RESULTS: The age, sex, proportion of patients with the first time operation, course of disease were no statistical significance between the observation group and the control group(P>0.05. The short-term effective rate of the observation group was 95.2%, while the short-term effective rate of the control group was 77.8%, the short-term efficiency differences between the two groups was statistical significance(χ2=4.100, P=0.043. The long-term cure rate of the observation group was 82.5%(34 cases, 52 eyes, recurrence rate was 17.5%(7 cases, 11 eyes, while the cure rate of the control group was 60.3%(25 cases, 38 eyes, recurrence rate was 39.7%(16 cases, 25 eyes, the difference of long term cure rate was statistical significance between the two groups(PCONCLUSION: The clinical curative effect of slack skin excision combined with orbicularis oculi muscle shortening in the treatment of senile inferior entropion is better than orbicularis muscle shortening operation, recommending application in the clinical.

Remote determination of the velocity index and mean streamwise velocity profiles

Science.gov (United States)

Johnson, E. D.; Cowen, E. A.

2017-09-01

When determining volumetric discharge from surface measurements of currents in a river or open channel, the velocity index is typically used to convert surface velocities to depth-averaged velocities. The velocity index is given by, k=Ub/Usurf, where Ub is the depth-averaged velocity and Usurf is the local surface velocity. The USGS (United States Geological Survey) standard value for this coefficient, k = 0.85, was determined from a series of laboratory experiments and has been widely used in the field and in laboratory measurements of volumetric discharge despite evidence that the velocity index is site-specific. Numerous studies have documented that the velocity index varies with Reynolds number, flow depth, and relative bed roughness and with the presence of secondary flows. A remote method of determining depth-averaged velocity and hence the velocity index is developed here. The technique leverages the findings of Johnson and Cowen (2017) and permits remote determination of the velocity power-law exponent thereby, enabling remote prediction of the vertical structure of the mean streamwise velocity, the depth-averaged velocity, and the velocity index.

Dyslipidemia and chronic inflammation markers are correlated with telomere length shortening in Cushing's syndrome.

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Anna Aulinas

Full Text Available Cushing's syndrome (CS increases cardiovascular risk (CVR and adipocytokine imbalance, associated with an increased inflammatory state. Telomere length (TL shortening is a novel CVR marker, associated with inflammation biomarkers. We hypothesized that inflammatory state and higher CVR in CS might be related to TL shortening, as observed in premature aging.To evaluate relationships between TL, CVR and inflammation markers in CS.In a cross-sectional study, 77 patients with CS (14 males, 59 pituitary-, 17 adrenal- and 1 ectopic-origin; 21 active disease and 77 age-, gender-, smoking-matched controls were included. Total white blood cell TL was measured by TRF-Southern technique. Clinical data and blood samples were collected (lipids, adrenal function, glucose. Adiponectin, interleukin-6 (IL6 and C-reactive protein (CRP were available in a subgroup of patients (n=32. Correlations between TL and clinical features were examined and multiple linear regression analysis was performed to investigate potential predictors of TL.Dyslipidemic CS had shorter TL than non-dyslipidemic subjects (7328±1274 vs 7957±1137 bp, p<0.05. After adjustment for age and body mass index, cured and active CS dyslipidemic patients had shorter TL than non-dyslipidemic CS (cured: 7187±1309 vs 7868±1104; active: 7203±1262 vs 8615±1056, respectively, p<0.05. Total cholesterol and triglycerides negatively correlated with TL (r-0.279 and -0.259, respectively, p<0.05, as well as CRP and IL6 (r-0.412 and -0.441, respectively, p<0.05. No difference in TL according the presence of other individual CVR factors (hypertension, diabetes mellitus, obesity were observed in CS or in the control group. Additional TL shortening was observed in dyslipidemic obese patients who were also hypertensive, compared to those with two or less CVR factors (6956±1280 vs 7860±1180, respectively, p<0.001. Age and dyslipidemia were independent negative predictors of TL.TL is shortened in dyslipidemic CS

Comparison of the Force-, Velocity- and Power-Time Curves Between the Concentric-Only and Eccentric-Concentric Bench Press Exercises.

Science.gov (United States)

Pérez-Castilla, Alejandro; Comfort, Paul; McMahon, John J; Pestaña-Melero, Francisco Luis; García-Ramos, Amador

2018-01-17

The aim of this study was to compare the temporal and mechanical variables between the concentric-only and eccentric-concentric bench press (BP) variants. Twenty-one men (age: 22.0±4.2 years, body mass: 73.4±7.7 kg, height: 177.2±8.0 cm; one-repetition maximum [1RM]: 1.12±0.12 kg⋅kg) were evaluated during the concentric-only and eccentric-concentric BP variants using 80% 1RM. Temporal (concentric phase duration, propulsive phase duration, and time to reach the maximum values of force, velocity, and power) and mechanical variables (force, velocity, and power), determined using a linear velocity transducer, were compared between both BP variants. All temporal variables were significantly lower during the eccentric-concentric BP compared to the concentric-only BP (P velocity and power were significantly higher for the eccentric-concentric BP compared to the concentric-only BP (all P velocity (ES: 0.40) and power (ES: 0.41). The stretch-shortening cycle (i.e., eccentric-concentric BP) mainly enhanced force production at the early portion of the concentric phase, but this potentiation effect gradually reduced over the latter part of the movement. Finally, force was higher for the concentric-only BP during 49% of the concentric phase duration. These results suggest that both BP variants should be included during resistance training programs in order to optimize force output at different points of the concentric phase.

Femtosecond pulse self-shortening in Kerr media: role of modulational instability in the spectrum formation

Science.gov (United States)

Grudtsyn, Ya. V.; Koribut, A. V.; Mikheev, L. D.; Trofimov, V. A.

2018-04-01

The mechanism of femtosecond pulse self-shortening in thin optical materials with Kerr nonlinearity is investigated. The experimentally observed spectral-angular distribution of the radiation intensity on the exit surface of a 1-mm-thick fused silica sample is compared with the results of numerical simulation based on solving the nonlinear Schrödinger equation for an electromagnetic wave with a transverse perturbation on the axis. Qualitative agreement between the calculated and experimental results confirms the hypothesis about the transient regime of multiple filamentation as a mechanism of femtosecond pulse self-shortening.

Psychometric properties of a shortened version of the Physical Self-Concept Questionnaire (PSQ-S).

Science.gov (United States)

Rodríguez-Fernández, Arantzazu; Axpe, Inge; Goñi, Alfredo

2015-01-01

The four-dimensional model of physical self-concept which differentiates the physical self-perceptions of ability, condition, attractiveness and strength is widely accepted. In the last two decades much research has been done on the physical self-concept and its relations with the psychological well-being/distress, anxiety disorders or Eating Behavior Disorders (EBD). To validate a shortened version of the Physical Self-Concept Questionnaire (PSQ-S) and verify its ability to discriminate between people with different levels of EBD. Responses of 1478 subjects between 13 and 21 years old to the shortened version of the PSQ were analyzed in order to check indexes of reliability and validity. Furthermore, the scores of 96 women aged 14 to 23 years old diagnosed of EBD were compared to 96 others without clinical diagnosis. The results indicate a reliability of 0.93 and confirm the tetrafactorial structure of the physical selfconcept. The highest physical self-concept is that of those without a clinical diagnosis of EBD. The Shortened-PSQ is a simple, reliable and suitable screening tool both for educational and clinical settings. It also provides a sufficient measure of physical self-concept for research purposes.

Strategies for shortening the output pulse of silicon photomultipliers

OpenAIRE

Antoranz Canales, Pedro; Miranda Pantoja, José Miguel; Yebras Rivera, José Manuel

2012-01-01

In this work, three strategies for shortening the output pulse of a silicon photomultiplier (SiPM) are reported. The first strategy is passive filtering, where band-pass filtering removes the lowest frequency components in the signal, getting a noticeable reduction in pulse width (a compression ratio of 10: 1 was obtained). In the second place, a reflectometric scheme is proposed where the amplified signal coming from the SiPM is injected into a signal splitter with one of its stubs connected...

3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells.

Directory of Open Access Journals (Sweden)

Yonit Hoffman

2016-02-01

Full Text Available Most mammalian genes often feature alternative polyadenylation (APA sites and hence diverse 3'UTR lengths. Proliferating cells were reported to favor APA sites that result in shorter 3'UTRs. One consequence of such shortening is escape of mRNAs from targeting by microRNAs (miRNAs whose binding sites are eliminated. Such a mechanism might provide proliferation-related genes with an expression gain during normal or cancerous proliferation. Notably, miRNA sites tend to be more active when located near both ends of the 3'UTR compared to those located more centrally. Accordingly, miRNA sites located near the center of the full 3'UTR might become more active upon 3'UTR shortening. To address this conjecture we performed 3' sequencing to determine the 3' ends of all human UTRs in several cell lines. Remarkably, we found that conserved miRNA binding sites are preferentially enriched immediately upstream to APA sites, and this enrichment is more prominent in pro-differentiation/anti-proliferative genes. Binding sites of the miR17-92 cluster, upregulated in rapidly proliferating cells, are particularly enriched just upstream to APA sites, presumably conferring stronger inhibitory activity upon shortening. Thus 3'UTR shortening appears not only to enable escape from inhibition of growth promoting genes but also to potentiate repression of anti-proliferative genes.

Development of an optimal velocity selection method with velocity obstacle

Energy Technology Data Exchange (ETDEWEB)

Kim, Min Geuk; Oh, Jun Ho [KAIST, Daejeon (Korea, Republic of)

2015-08-15

The Velocity obstacle (VO) method is one of the most well-known methods for local path planning, allowing consideration of dynamic obstacles and unexpected obstacles. Typical VO methods separate a velocity map into a collision area and a collision-free area. A robot can avoid collisions by selecting its velocity from within the collision-free area. However, if there are numerous obstacles near a robot, the robot will have very few velocity candidates. In this paper, a method for choosing optimal velocity components using the concept of pass-time and vertical clearance is proposed for the efficient movement of a robot. The pass-time is the time required for a robot to pass by an obstacle. By generating a latticized available velocity map for a robot, each velocity component can be evaluated using a cost function that considers the pass-time and other aspects. From the output of the cost function, even a velocity component that will cause a collision in the future can be chosen as a final velocity if the pass-time is sufficiently long enough.

Investigation on shortening fabrication process of instrumented irradiation capsule of JMTR

International Nuclear Information System (INIS)

Nagata, Hiroshi; Inoue, Shuichi; Yamaura, Takayuki; Tsuchiya, Kunihiko; Nagao, Yoshiharu

2013-06-01

Refurbishment of The Japan Materials Testing Reactor (JMTR) was completed in FY2010. For damage caused by the 2011 off the Pacific coast of Tohoku Earthquake, the repair of facilities was completed in October 2012. Currently, the JMTR is in preparation for restart. Irradiation tests for LWRs safety research, science and technologies and production of RI for medical diagnosis medicine, etc. are expected after the JMTR restart. On the other hand, aiming at the attractive irradiation testing reactor, the usability improvement has been discussed. As a part of the usability improvement, shortening of turnaround time to get irradiation results from an application for irradiation use was discussed focusing on the fabrication process of irradiation capsules, where the fabrication process was analyzed and reviewed by referring a trial fabrication of the mockup capsule. As a result, it was found that the turnaround time can be shortened 2 months from fabrication period of 6 months with communize of irradiation capsule parts, application of ready-made instrumentation including the sheath heater, reconsideration of inspection process, etc. (author)

Increasing flux rate to shorten leaching period and ramp-up production

Science.gov (United States)

Ngantung, Billy; Agustin, Riska; Ravi'i

2017-01-01

J Resources Bolaang Mongondow (JBRM) has operated a dynamic heap leach in its Bakan Gold Mine since late 2013. After successfully surpassing its name plate capacity of 2.6 MT/annum in 2014, the clayey and transition ore become the next operational challenge. The presence of transition and clayey ore requires longer leaching period, hence reducing the leach pad capacity which then caused reduced production. Maintaining or even increasing production with such longer leaching ore types can be done by expanding the leach pad area which means an additional capital investment, and/or shortening the leaching cycle which compromise a portion of gold extraction. JBRM has been successfully increasing the leach pad production from 2.6 MT/annum to 3.8 MT/annum, whilst improving the gold extraction from around 70% to around 80%. This was achieved by managing the operation of the leach pad which is shortening the leach cycle by identifying and combining the optimal flux rate application versus the tonne processed in each cell, at no capital investment for expanding the cell capacity.

Chordee and Penile Shortening Rather Than Voiding Function Are Associated With Patient Dissatisfaction After Urethroplasty.

Science.gov (United States)

Maciejewski, Conrad C; Haines, Trevor; Rourke, Keith F

2017-05-01

To identify factors that predict patient satisfaction after urethroplasty by prospectively examining patient-reported quality of life scores using 3 validated instruments. A 3-part prospective survey consisting of the International Prostate Symptom Score (IPSS), the International Index of Erectile Function (IIEF) score, and a urethroplasty quality of life survey was completed by patients who underwent urethroplasty preoperatively and at 6 months postoperatively. The quality of life score included questions on genitourinary pain, urinary tract infection (UTI), postvoid dribbling, chordee, shortening, overall satisfaction, and overall health. Data were analyzed using descriptive statistics, paired t test, univariate and multivariate logistic regression analyses, and Wilcoxon signed-rank analysis. Patients were enrolled in the study from February 2011 to December 2014, and a total of 94 patients who underwent a total of 102 urethroplasties completed the study. Patients reported statistically significant improvements in IPSS (P Wilcoxon signed-rank analysis revealed significant improvements in pain scores (P = .02), UTI (P 4 cm and the absence of UTI, pain, shortening, and chordee as predictors of patient satisfaction. Multivariate analysis of quality of life domain scores identified absence of shortening and absence of chordee as independent predictors of patient satisfaction following urethroplasty (P < .01). Patient voiding function and quality of life improve significantly following urethroplasty, but improvement in voiding function is not associated with patient satisfaction. Chordee status and perceived penile shortening impact patient satisfaction, and should be included in patient-reported outcome measures. Copyright © 2017 Elsevier Inc. All rights reserved.

Muscle damage induced by stretch-shortening cycle exercise.

Science.gov (United States)

Kyröläinen, H; Takala, T E; Komi, P V

1998-03-01

Strenuous stretch-shortening cycle exercise was used as a model to study the leakage of proteins from skeletal muscle. The analysis included serum levels of creatine kinase (S-CK), myoglobin (S-Mb), and carbonic anhydrase (S-CA III). Blood samples from power- (N=11) and endurance-trained (N=10) athletes were collected before, 0, and 2 h after the exercise, which consisted of a total of 400 jumps. The levels of all determined myocellular proteins increased immediately after the exercise (P exercise, and the ratio of S-CA III and S-Mb decreased (P recruitment order of motor units, and/or differences in training background.

Bit Error Rate Minimizing Channel Shortening Equalizers for Single Carrier Cyclic Prefixed Systems

National Research Council Canada - National Science Library

Martin, Richard K; Vanbleu, Koen; Ysebaert, Geert

2007-01-01

.... Previous work on channel shortening has largely been in the context of digital subscriber lines, a wireline system that allows bit allocation, thus it has focused on maximizing the bit rate for a given bit error rate (BER...

A Possible Differentially Shortened Strike-slip Plate Boundary: the Okhotsk Plate Example.

Science.gov (United States)

Hindle, D.; Egorov, V.; Mackey, K. G.; Fujita, K.

2004-12-01

The Okhotsk plate has been postulated based on a combination of GPS geodetic inversions (REVEL1), seimsicity, geologic and lineament data. Lying between the North American and Eurasian plates, its northwestern corner would appear to be undergoing compression in a scissors motion between the two bounding plates. Extrusion tectonics along multiple, large strike-slip faults within the Okhotsk plate itself have been suggested to allow the escape of material away from the apex of Eurasia-North America. The plate boundary between Okhotsk and North America has been suggested to be diffuse, based on widely scattered minor seismicity. However, the large, left lateral, Ulakhan fault has also been suggested as a candidate plate boundary. We present field geological and geomorphological evidence of the partitioning of deformation between the Ulakhan fault, and several parallel and oblique, linked faults. The Ulakhan fault strand appears to have a maximum displacement of 24 km based on river valley offsets and closing large pull apart basins. Some of the displacement from the Ulakhan fault appears relayed into the plate margin along oblique trending, thrust/oblique slip faults. Estimated shortening over these faults is equivalent to the amount of shortening relayed into the plate margin from the plate boundary. There may be several thrust/oblique slip faults along the Ulakhan fault, which leads to the interesting situation of a segmented, strike-slip plate boundary being actively shortened in a margin parallel direction. This may be the result of postulated extrusion of the Okhotsk plate due to North America/Eurasia convergence. Such a situation would have important consequences for the interpretation of GPS data in a plate tectonic context.

Effect of kinetically altering a repetition via the use of chain resistance on velocity during the bench press.

Science.gov (United States)

Baker, Daniel G; Newton, Robert U

2009-10-01

It is theorized that the force and velocity profile of a repetition performed during a standard barbell exercise may be altered by substituting suspended chains for some portion of the total resistance. The purpose of this study was to document the alterations in lifting velocity that occur when the bench press exercise is performed as standard (BP) or with the substitution of resistance via chains draped over the barbell (BP+CH). Thirteen professional rugby league players participated in this study as part of their usual training program. Each subject performed 2 sets of 3 repetitions under the following conditions: The BP+CH condition, where the barbell resistance of 60% 1RM (repetition maximum) was supplemented by 17.5-kg in chains draped over the barbell (total resistance was about 75% 1RM), and the BP condition, where the total resistance was the same but was constituted in the form of standard barbell weights. The BP+CH condition resulted in increases in mean and peak concentric lifting velocities of around 10% in both sets as compared to both BP sets. Eccentric peak velocities were more varied in response, but generally the addition of chain resistance could be said to allow for increased velocities. The result may be partially explained by the eccentric unloading that occurs as the chain links furl upon the floor in the latter stages of the eccentric range. This eccentric unloading precipitates a more rapid stretch-shorten cycle (SSC) transition and possibly a within-repetition postactivation potentiation (PAP) that allows the subject to utilize faster lifting velocities in the initial concentric portion, which flow through to the remainder of the concentric phase. Therefore the use of chains appears warranted when athletes need to lift heavy resistances explosively.

3’UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells

Science.gov (United States)

Hoffman, Yonit; Bublik, Debora Rosa; P. Ugalde, Alejandro; Elkon, Ran; Biniashvili, Tammy; Agami, Reuven; Oren, Moshe; Pilpel, Yitzhak

2016-01-01

Most mammalian genes often feature alternative polyadenylation (APA) sites and hence diverse 3’UTR lengths. Proliferating cells were reported to favor APA sites that result in shorter 3’UTRs. One consequence of such shortening is escape of mRNAs from targeting by microRNAs (miRNAs) whose binding sites are eliminated. Such a mechanism might provide proliferation-related genes with an expression gain during normal or cancerous proliferation. Notably, miRNA sites tend to be more active when located near both ends of the 3’UTR compared to those located more centrally. Accordingly, miRNA sites located near the center of the full 3’UTR might become more active upon 3'UTR shortening. To address this conjecture we performed 3' sequencing to determine the 3' ends of all human UTRs in several cell lines. Remarkably, we found that conserved miRNA binding sites are preferentially enriched immediately upstream to APA sites, and this enrichment is more prominent in pro-differentiation/anti-proliferative genes. Binding sites of the miR17-92 cluster, upregulated in rapidly proliferating cells, are particularly enriched just upstream to APA sites, presumably conferring stronger inhibitory activity upon shortening. Thus 3’UTR shortening appears not only to enable escape from inhibition of growth promoting genes but also to potentiate repression of anti-proliferative genes. PMID:26908102

Auditory velocity discrimination in the horizontal plane at very high velocities.

Science.gov (United States)

Frissen, Ilja; Féron, François-Xavier; Guastavino, Catherine

2014-10-01

We determined velocity discrimination thresholds and Weber fractions for sounds revolving around the listener at very high velocities. Sounds used were a broadband white noise and two harmonic sounds with fundamental frequencies of 330 Hz and 1760 Hz. Experiment 1 used velocities ranging between 288°/s and 720°/s in an acoustically treated room and Experiment 2 used velocities between 288°/s and 576°/s in a highly reverberant hall. A third experiment addressed potential confounds in the first two experiments. The results show that people can reliably discriminate velocity at very high velocities and that both thresholds and Weber fractions decrease as velocity increases. These results violate Weber's law but are consistent with the empirical trend observed in the literature. While thresholds for the noise and 330 Hz harmonic stimulus were similar, those for the 1760 Hz harmonic stimulus were substantially higher. There were no reliable differences in velocity discrimination between the two acoustical environments, suggesting that auditory motion perception at high velocities is robust against the effects of reverberation. Copyright © 2014 Elsevier B.V. All rights reserved.

Shortened carbon nanotubes and their influence on the electrical properties of polymer nanocomposites

NARCIS (Netherlands)

Inam, F.; Reece, M.J.; Peijs, A.A.J.M.

2012-01-01

Multi-wall carbon nanotubes of medium length (mCNTs) were aggressively tip-ultrasonicated to produce shortened and damaged carbon nanotubes (xCNTs). High-resolution electron microscopic analysis was performed to measure the dimensions of carbon nanotubes (CNTs). Thermo-gravimetric analysis and Raman

A shortened protocol for assessing cognitive bias in rats.

Science.gov (United States)

Brydges, Nichola M; Hall, Lynsey

2017-07-15

Reliable measurement of affective state in animals is a significant goal of animal welfare. Such measurements would also improve the validity of pre-clinical mental health research which relies on animal models. However, at present, affective states in animals are inaccessible to direct measurement. In humans, changes in cognitive processing can give reliable indications of emotional state. Therefore, similar techniques are increasingly being used to gain proxy measures of affective states in animals. In particular, the 'cognitive bias' assay has gained popularity in recent years. Major disadvantages of this technique include length of time taken for animals to acquire the task (typically several weeks), negative experiences associated with task training, and issues of motivation. Here we present a shortened cognitive bias protocol using only positive reinforcers which must actively be responded to. The protocol took an average of 4days to complete, and produced similar results to previous, longer methods (minimum 30days). Specifically, rats housed in standard laboratory conditions demonstrated negative cognitive biases when presented with ambiguous stimuli, and took longer to make a decision when faced with an ambiguous stimulus. Compared to previous methods, this protocol is significantly shorter (average 4days vs. minimum 30days), utilises only positive reinforcers to avoid inducing negative affective states, and requires active responses to all cues, avoiding potential confounds of motivational state. We have successfully developed a shortened cognitive bias protocol, suitable for use with laboratory rats. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

Comparison of hydrogenated vegetable shortening and nutritionally complete high fat diet on limited access-binge behavior in rats

OpenAIRE

Davis, Jon F.; Melhorn, Susan J.; Heiman, Justin U.; Tschöp, Matthias H.; Clegg, Deborah J.; Benoit, Stephen C.

2007-01-01

Previous studies have suggested that intermittent exposure to hydrogenated vegetable shortening yields a binge/compensate pattern of feeding in rats. The present study was designed to assess whether rats would exhibit similar patterns of intake when given intermittent access to a nutritionally complete high-fat diet. Four groups of rats received varying exposure to either hydrogenated vegetable shortening or high-fat diet for 8 consecutive weeks. Animals were given daily and intermittent acce...

Cost and cost-effectiveness of tuberculosis treatment shortening: a model-based analysis.

Science.gov (United States)

Gomez, G B; Dowdy, D W; Bastos, M L; Zwerling, A; Sweeney, S; Foster, N; Trajman, A; Islam, M A; Kapiga, S; Sinanovic, E; Knight, G M; White, R G; Wells, W A; Cobelens, F G; Vassall, A

2016-12-01

Despite improvements in treatment success rates for tuberculosis (TB), current six-month regimen duration remains a challenge for many National TB Programmes, health systems, and patients. There is increasing investment in the development of shortened regimens with a number of candidates in phase 3 trials. We developed an individual-based decision analytic model to assess the cost-effectiveness of a hypothetical four-month regimen for first-line treatment of TB, assuming non-inferiority to current regimens of six-month duration. The model was populated using extensive, empirically-collected data to estimate the economic impact on both health systems and patients of regimen shortening for first-line TB treatment in South Africa, Brazil, Bangladesh, and Tanzania. We explicitly considered 'real world' constraints such as sub-optimal guideline adherence. From a societal perspective, a shortened regimen, priced at USD1 per day, could be a cost-saving option in South Africa, Brazil, and Tanzania, but would not be cost-effective in Bangladesh when compared to one gross domestic product (GDP) per capita. Incorporating 'real world' constraints reduces cost-effectiveness. Patient-incurred costs could be reduced in all settings. From a health service perspective, increased drug costs need to be balanced against decreased delivery costs. The new regimen would remain a cost-effective option, when compared to each countries' GDP per capita, even if new drugs cost up to USD7.5 and USD53.8 per day in South Africa and Brazil; this threshold was above USD1 in Tanzania and under USD1 in Bangladesh. Reducing the duration of first-line TB treatment has the potential for substantial economic gains from a patient perspective. The potential economic gains for health services may also be important, but will be context-specific and dependent on the appropriate pricing of any new regimen.

Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level.

Science.gov (United States)

Humphreys, Kathryn L; Esteves, Kyle; Zeanah, Charles H; Fox, Nathan A; Nelson, Charles A; Drury, Stacy S

2016-12-30

Studies examining the association between early adversity and longitudinal changes in telomere length within the same individual are rare, yet are likely to provide novel insight into the subsequent lasting effects of negative early experiences. We sought to examine the association between institutional care history and telomere shortening longitudinally across middle childhood and into adolescence. Buccal DNA was collected 2-4 times, between the ages of 6 and 15 years, in 79 children enrolled in the Bucharest Early Intervention Project (BEIP), a longitudinal study exploring the impact of early institutional rearing on child health and development. Children with a history of early institutional care (n=50) demonstrated significantly greater telomere shortening across middle childhood and adolescence compared to never institutionalized children (n=29). Among children with a history of institutional care, randomization to high quality foster care was not associated with differential telomere attrition across development. Cross-sectional analysis of children randomized to the care as usual group indicated shorter telomere length was associated with greater percent of the child's life spent in institutional care up to age 8. These results suggest that early adverse care from severe psychosocial deprivation may be embedded at the molecular genetic level through accelerated telomere shortening. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Superconducting RF for Low-Velocity and Intermediate-Velocity Beams

CERN Document Server

Grimm, Terry L

2005-01-01

Existing superconducting radio frequency (SRF) linacs are used to accelerate ions (protons through uranium) with velocities less than about 15% the speed of light, or electrons with velocities approximately equal to the speed of light. In the last ten years, prototype SRF cavities have completely covered the remaining range of velocities. They have demonstrated that SRF linacs will be capable of accelerating electrons from rest up to the speed of light, and ions from less than 1% up to the speed of light. When the Spallation Neutron Source is operational, SRF ion linacs will have covered the full range of velocities except for v/c ~ 0.15 to v/c ~ 0.5. A number of proposed projects (RIA, EURISOL) would span the latter range of velocities. Future SRF developments will have to address the trade-offs associated with a number of issues, including high gradient operation, longitudinal and transverse acceptance, microphonics, Lorentz detuning, operating temperature, cryogenic load, number of gaps or cells per cavity...

Critical velocities in He II for independently varied superfluid and normal fluid velocities

International Nuclear Information System (INIS)

Baehr, M.L.

1984-01-01

Experiments were performed to measure the critical velocity in pure superflow and compare to the theoretical prediction; to measure the first critical velocity for independently varied superfluid and normal fluid velocities; and to investigate the propagation of the second critical velocity from the thermal counterflow line through the V/sub n/,-V/sub s/ quadrant. The experimental apparatus employed a thermal counterflow heater to adjust the normal fluid velocity, a fountain pump to vary the superfluid velocity, and a level sensing capacitor to measure the superfluid velocity. The results of the pure superfluid critical velocity measurements indicate that this velocity is temperature independent contrary to Schwarz's theory. It was found that the first critical velocity for independently varied V/sub n/ and V/sub s/ could be described by a linear function of V/sub n/ and was otherwise temperature independent. It was found that the second critical velocity could only be distinguished near the thermal counterflow line

Charcot arthropathy of the lumbar spine treated using one-staged posterior three-column shortening and fusion.

Science.gov (United States)

David, Kenny Samuel; Agarwala, Amit Omprakash; Rampersaud, Yoga Raja

2010-06-15

Case report. We present a case of lumbar Charcot arthropathy successfully treated surgically using posterior 3-column resection, spinal shortening, and fusion. The operative treatment of Charcot arthropathy of the spine has conventionally been a combination of anterior and posterior surgery. The morbidity associated with these surgical procedures can be considerable. A posterior-only approach to the problem would avoid the additional morbidity associated with an anterior approach. We present a case of lumbar Charcot arthropathy with deformity treated successfully using such a procedure. Discussion of the patient's clinical and radiologic history, the technical merits of the operative intervention and a review of the relevant background literature are presented. A multilevel, single-stage, posterior 3-column resection with primary shortening and instrumented fusion augmented with rhBMP2 in a multiply operated patient with deformity provided a optimal biologic and mechanical environment for healing of the Charcot arthropathy and improved the sagittal and coronal profile of the spine. A single-stage, multilevel, posterior 3-column resection and primary shortening can be a useful surgical strategy in symptomatic patients with Charcot arthropathy of the spine.

Mean Velocity vs. Mean Propulsive Velocity vs. Peak Velocity: Which Variable Determines Bench Press Relative Load With Higher Reliability?

Science.gov (United States)

García-Ramos, Amador; Pestaña-Melero, Francisco L; Pérez-Castilla, Alejandro; Rojas, Francisco J; Gregory Haff, G

2018-05-01

García-Ramos, A, Pestaña-Melero, FL, Pérez-Castilla, A, Rojas, FJ, and Haff, GG. Mean velocity vs. mean propulsive velocity vs. peak velocity: which variable determines bench press relative load with higher reliability? J Strength Cond Res 32(5): 1273-1279, 2018-This study aimed to compare between 3 velocity variables (mean velocity [MV], mean propulsive velocity [MPV], and peak velocity [PV]): (a) the linearity of the load-velocity relationship, (b) the accuracy of general regression equations to predict relative load (%1RM), and (c) the between-session reliability of the velocity attained at each percentage of the 1-repetition maximum (%1RM). The full load-velocity relationship of 30 men was evaluated by means of linear regression models in the concentric-only and eccentric-concentric bench press throw (BPT) variants performed with a Smith machine. The 2 sessions of each BPT variant were performed within the same week separated by 48-72 hours. The main findings were as follows: (a) the MV showed the strongest linearity of the load-velocity relationship (median r = 0.989 for concentric-only BPT and 0.993 for eccentric-concentric BPT), followed by MPV (median r = 0.983 for concentric-only BPT and 0.980 for eccentric-concentric BPT), and finally PV (median r = 0.974 for concentric-only BPT and 0.969 for eccentric-concentric BPT); (b) the accuracy of the general regression equations to predict relative load (%1RM) from movement velocity was higher for MV (SEE = 3.80-4.76%1RM) than for MPV (SEE = 4.91-5.56%1RM) and PV (SEE = 5.36-5.77%1RM); and (c) the PV showed the lowest within-subjects coefficient of variation (3.50%-3.87%), followed by MV (4.05%-4.93%), and finally MPV (5.11%-6.03%). Taken together, these results suggest that the MV could be the most appropriate variable for monitoring the relative load (%1RM) in the BPT exercise performed in a Smith machine.

A chopper system for shortening the duration of pulsed supersonic beams seeded with NO or Br2 down to 13 μs.

Science.gov (United States)

Lam, Jessica; Rennick, Christopher J; Softley, Timothy P

2015-05-01

A chopper wheel construct is used to shorten the duration of a molecular beam to 13 μs. Molecular beams seeded with NO or with Br2 and an initial pulse width of ≥200 μs were passed through a spinning chopper wheel, which was driven by a brushless DC in vacuo motor at a range of speeds, from 3000 rpm to 80,000 rpm. The resulting duration of the molecular-beam pulses measured at the laser detection volume ranged from 80 μs to 13 μs and was the same for both NO and Br2. The duration is consistent with a simple analytical model, and the minimum pulse width measured is limited by the spreading of the beam between the chopper and the detection point as a consequence of the longitudinal velocity distribution of the beam. The setup adopted here effectively eliminates buildup of background gas without the use of a differential pumping stage, and a clean narrow pulse is obtained with low rotational temperature.

Vastus lateralis surface and single motor unit EMG following submaximal shortening and lengthening contractions

NARCIS (Netherlands)

Altenburg, T.M.; de Ruiter, C.J.; Verdijk, P.W.L.; van Mechelen, W.; de Haan, A.

2008-01-01

A single shortening contraction reduces the force capacity of muscle fibers, whereas force capacity is enhanced following lengthening. However, how motor unit recruitment and discharge rate (muscle activation) are adapted to such changes in force capacity during submaximal contractions remains

Effect of Pre-gelatinized Wheat Starch on Physical and Rheological Properties of Shortened Cake Batter and Cake Texture

Directory of Open Access Journals (Sweden)

F. Ebrahimi

2016-10-01

Full Text Available The focus of this study was the effect of 1.5%, 3% and 4.5% pre-gelatinized wheat starch (based on the total weight of cake batter on improving the qualitative properties of shortened cake batter. Specific volume and viscosity of the shortened cake batter were measured for controls, 1.5%, 3% and 4.5% gelatinized starch; some important properties such as texture and sensory evaluation were examined. By increasing pre-gelatinized wheat starch used in the batter, a significant difference was observed in the rheological properties of the batter. Cake batter properties were found improved compared to the control samples. The sample with 3% pre-gelatinized starch had a lower viscosity than other treatments. The treatment with 4.5% pre-gelatinized starch had the lowest specific volume compared to other treatments. The overall results showed that the shortened cake with 3% pre-gelatinized starch was the best treatment in terms of texture and sensory evaluation factors.

Diffraction imaging and velocity analysis using oriented velocity continuation

KAUST Repository

Decker, Luke

2014-08-05

We perform seismic diffraction imaging and velocity analysis by separating diffractions from specular reflections and decomposing them into slope components. We image slope components using extrapolation in migration velocity in time-space-slope coordinates. The extrapolation is described by a convection-type partial differential equation and implemented efficiently in the Fourier domain. Synthetic and field data experiments show that the proposed algorithm is able to detect accurate time-migration velocities by automatically measuring the flatness of events in dip-angle gathers.

Trans Fatty Acid content in Danish margarines and shortenings

DEFF Research Database (Denmark)

Leth, Torben; Bysted, Anette; Hansen, Kirsten

2003-01-01

with similar investigations in 1992 and 1995. A gradual decline of TFA in Danish margarines was observed. From 1992 to 1995, a reduction of TFA from 10.4 to 3.6% took place in margarines with 20-40% linoleic acid. In 1999, TFA was practically absent in all the margarines, but it remained unchanged...... in shortenings, averaging about 6-7%. Long-chain TFA from hydrogenated,fish oil, although present in 13 brands in 1995, were not found at all in the 1999 samples. Trans-linoleic acids or CLA were not found. The reduction in TFA content in margarines has not resulted in a systematic change over the years...

On the shortening of Indian summer monsoon season in a warming scenario

Science.gov (United States)

Sabeerali, C. T.; Ajayamohan, R. S.

2018-03-01

Assessing the future projections of the length of rainy season (LRS) has paramount societal impact considering its potential to alter the seasonal mean rainfall over the Indian subcontinent. Here, we explored the projections of LRS using both historical and Representative Concentration Pathways 8.5 (RCP8.5) simulations of the Coupled Model Intercomparison Project Phase5 (CMIP5). RCP8.5 simulations project shortening of the LRS of Indian summer monsoon by altering the timing of onset and withdrawal dates. Most CMIP5 RCP8.5 model simulations indicate a faster warming rate over the western tropical Indian Ocean compared to other regions of the Indian Ocean. It is found that the pronounced western Indian Ocean warming and associated increase in convection results in warmer upper troposphere over the Indian Ocean compared to the Indian subcontinent, reducing the meridional gradient in upper tropospheric temperature (UTT) over the Asian summer monsoon (ASM) domain. The weakening of the meridional gradient in UTT induces weakening of easterly vertical wind shear over the ASM domain during first and last phase of monsoon, facilitate delayed (advanced) monsoon onset (withdrawal) dates, ensues the shortening of LRS of the Indian summer monsoon in a warming scenario.

Lactose tolerance test shortened to 30 minutes: an exploratory study of its feasibility and impact

Directory of Open Access Journals (Sweden)

José Luis Domínguez-Jiménez

2014-06-01

Full Text Available Introduction: Lactose malabsorption (LM is a very common condition with a high prevalence in our setting. Lactose tolerance test (LTT is a basic, affordable test for diagnosis that requires no complex technology. It has been recently shown that this test can be shortened to 3 measurements (baseline, 30 min, 60 min with no impact on final results. The purpose of our study was to assess the feasibility and benefits of LTT simplification and shortening to 30 min, as well as the financial impact entailed. Material and methods: A multicenter, observational study of consecutive patients undergoing LTT for LM suspicion. Patients received 50 g of lactose following a fasting period of 12 h, and had blood collected from a vein at all 3 time points for the measurement of blood glucose (mg/dl. Differences between the shortened and complete test forms were analyzed using McNemar's test. A comparison of blood glucose levels between patients with normal and abnormal results was performed using Student's T-test for independent mean values. Consistency was assessed using the kappa index. A p < 0.05 was considered to be statistically significant. Results: A total of 270 patients (69.6% females were included, with a mean age of 39.9 ± 16 years. LTT was abnormal for 151 patients (55.9%. We observed no statistically significant differences in baseline blood glucose levels between patients with normal and abnormal LTT results (p = 0.13; however, as was to be expected, such differences were obvious for the remaining time points (p < 0.01. Deleting blood glucose measurements at 60 minutes only led to overdiagnose LM (false positive results in 6 patients (2.22 %, with a kappa index of 0.95 (95% CI: 0.92-0.99 (p < 0.001 versus the complete test. Suppressing measurements at 60 min would have saved at least € 7,726. Conclusion: The shortening of LTT to only 2 measurements (baseline and 30-min hardly leads to any differences in final results, and would entail savings in

Dose-effect relationships for fife shortening, tumorigenesis, and systemic injuries in mice irradiated with fission neutron or 60Co gamma radiation

International Nuclear Information System (INIS)

Ainsworth, E.J.; Fry, R.J.M.; Williamson, F.S.; Brennan, P.C.; Stearner, S.P.; Yang, V.V.; Crouse, D.A.; Rust, J.H.; Borak, T.B.

1977-01-01

The objective of this research is to provide additional data on life shortening, neoplastic and non-neoplastic diseases, and other systematic injuries necessary for the determination of dose-response relationships. The data are used to test existing predictive models and formulate new models which may assist with radiation risk assessment. Late somatic effects of fission neutrons from the JANUS reactor or from cobalt-60 gamma radiation are evaluated in young adult B6CF 1 mice that receive either a range of single doses or protracted doses at low dose rates; the protracted irradiation is administered over a 6-month period. After single doses of gamma radiation the relationship between radiation dose and percent life shortening appears linear whereas after single doses of fission spectrum neutrons a non-linear dose response is observed. These results suggest that estimates of radiation risk for fission spectrum neutrons should take into account the following: the curvilinearity of the neutron dose-response curve for life shortening, and the increased life shortening produced by neutron dose fractionation

Referencing geostrophic velocities using ADCP data Referencing geostrophic velocities using ADCP data

Directory of Open Access Journals (Sweden)

Isis Comas-Rodríguez

2010-06-01

Full Text Available Acoustic Doppler Current Profilers (ADCPs have proven to be a useful oceanographic tool in the study of ocean dynamics. Data from D279, a transatlantic hydrographic cruise carried out in spring 2004 along 24.5°N, were processed, and lowered ADCP (LADCP bottom track data were used to assess the choice of reference velocity for geostrophic calculations. The reference velocities from different combinations of ADCP data were compared to one another and a reference velocity was chosen based on the LADCP data. The barotropic tidal component was subtracted to provide a final reference velocity estimated by LADCP data. The results of the velocity fields are also shown. Further studies involving inverse solutions will include the reference velocity calculated here.

Free-surface velocity measurements using an optically recording velocity interferometer

International Nuclear Information System (INIS)

Lu Jianxin; Wang Zhao; Liang Jing; Shan Yusheng; Zhou Chuangzhi; Xiang Yihuai; Lu Ze; Tang Xiuzhang

2006-01-01

An optically recording velocity interferometer system (ORVIS) was developed for the free-surface velocity measurements in the equation of state experiments. The time history of free-surface velocity could be recorded by the electronic streak camera. In the experiments, ORVIS got a 179 ps time resolution, and a higher time resolution could be got by minimizing the delay time. The equation of state experiments were carried out on the high power excimer laser system called 'Heaven I' with laser wavelength of 248.4 nm, pulse duration of 25 ns and maximum energy 158 J. Free-surface velocity of 20 μm thick iron got 3.86 km/s with laser intensity of 6.24 x 10 11 W·cm -2 , and free-surface velocity of 100 μm thick aluminum with 100 μm CH foil at the front got 2.87 km/s with laser intensity 7.28 x 10 11 W·cm -2 . (authors)

On linear relationship between shock velocity and particle velocity

International Nuclear Information System (INIS)

Dandache, H.

1986-11-01

We attempt to derive the linear relationship between shock velocity U s and particle velocity U p from thermodynamic considerations, taking into account an ideal gas equation of state and a Mie-Grueneisen equation of state for solids. 23 refs

The Spiritual Well-Being Scale : Psychometric Evaluation of the Shortened Version in Czech Adolescents

NARCIS (Netherlands)

Malinakova, Klara; Kopcakova, Jaroslava; Kolarcik, Peter; Geckova, Andrea Madarasova; Polackova Solcova, Iva; Husek, Vit; Kracmarova, Lucie Kluzova; Dubovska, Eva; Kalman, Michal; Puzova, Zuzana; van Dijk, Jitse P.; Tavel, Peter

The aim of this study was to psychometrically evaluate the shortened version of the Spiritual Well-Being Scale (SWBS) in Czech adolescents. A nationally representative sample of 4217 adolescents participated in the 2014 Health Behaviour in School-aged Children survey. The internal consistency of the

Attitudes toward Seeking Professional Psychological Help: A Shortened Form and Considerations for Research.

Science.gov (United States)

Fischer, Edward H.; Farina, Amerigo

1995-01-01

Tested a new, shortened scale for measuring willingness to seek help from mental health professionals. Scores correlated with the 29-item scale developed by Fischer and Turner (1970); the new scale's brevity (10 items) should make it easier and less obtrusive for use in research. Discusses the need for further studies on attitudes toward…

Determination of the filtration velocities and mean velocity in ground waters using radiotracers

International Nuclear Information System (INIS)

Duran P, Oscar; Diaz V, Francisco; Heresi M, Nelida

1994-01-01

An experimental method to determine filtration, or, Darcy velocity and mean velocity in underground waters using radiotracers, is described. After selecting the most appropriate tracers, from 6 chemical compounds, to measure water velocity, a method to measure filtration velocity was developed. By fully labelling the water column with 2 radioisotopes, Br and tritium, almost identical values were obtained for the aquifer filtration velocity in the sounding S1. This value was 0.04 m/d. Field porosity was calculated at 11% and mean velocity at 0.37 m.d. With the filtration velocity value and knowing the hydraulic variation between the soundings S1 and S2 placed at 10 meters, field permeability was estimated at 2.4 x 10 m/s. (author)

Study of imaging time shortening in Whole Heart MRCA. Evaluation of slice thickness

International Nuclear Information System (INIS)

Iwai, Mitsuhiro; Tateishi, Toshiki; Takeda, Soji; Hayashi, Ryuji

2005-01-01

A series of examinations in cardiac MR imaging, such as cine, perfusion, MR coronary angiography (MRCA) and viability, is generally known as One Stop Cardiac Examination. It takes about 40 to 60 minutes to perform One Stop Cardiac Examination, and Whole Heart MRCA accounts for most of the examination time. Therefore, we aimed to shorten imaging time of Whole Heart MRCA, especially in a large imaging area such as that in the case of the postoperative evaluation of a bypass graft, by investigating the depiction of a diameter of mimic blood vessels as changing the slice thickness of Whole Heart MRCA. The results showed that the maximum slice thickness of about 1 mm was excellent considering the diameters of actual coronary arteries are about 3 mm. In this study, we could grasp the relationships among slice thickness of Whole Heart MRCA, the diameter of a blood vessel, and shortened examination time. We suggested that it was useful for selecting the suitable sequence depending on a patient's conditions. (author)

Two-stage revision of infected hip arthroplasty using a shortened post-operative course of antibiotics.

LENUS (Irish Health Repository)

McKenna, Paul B

2009-04-01

We present a series of 30 consecutive patients with 31 infected total hip arthroplasties treated by a single surgeon over a 4-year period in whom a shortened post-operative course of antimicrobial chemotherapy was used.

Radial velocity asymmetries from jets with variable velocity profiles

International Nuclear Information System (INIS)

Cerqueira, A. H.; Vasconcelos, M. J.; Velazquez, P. F.; Raga, A. C.; De Colle, F.

2006-01-01

We have computed a set of 3-D numerical simulations of radiatively cooling jets including variabilities in both the ejection direction (precession) and the jet velocity (intermittence), using the Yguazu-a code. In order to investigate the effects of jet rotation on the shape of the line profiles, we also introduce an initial toroidal rotation velocity profile. Since the Yguazu-a code includes an atomic/ionic network, we are able to compute the emission coefficients for several emission lines, and we generate line profiles for the Hα, [O I]λ6300, [S II]λ6716 and [N II]λ6548 lines. Using initial parameters that are suitable for the DG Tau microjet, we show that the computed radial velocity shift for the medium-velocity component of the line profile as a function of distance from the jet axis is strikingly similar for rotating and non-rotating jet models

Magnitude of crustal shortening and structural framework of the easternmost Himalayan orogen, northern Indo-Burma Ranges of northeastern India

Science.gov (United States)

Haproff, P. J.; Yin, A.

2016-12-01

Along-strike variation in crustal shortening throughout the Himalayan orogen has been attributed to (1) diachronous, eastward-increasing convergence, or (2) localized controls including pre-collisional stratigraphic configuration and climate. In this study, we present new geologic maps and balanced cross-sections across the easternmost segment of the Himalayan orogen, the N-S-trending N. Indo-Burma Ranges of northeastern India. First order structures are NE-dipping, km-wide ductile thrust shear zones with mylonitic fabrics indicating top-to-the SW motion. Major structures include the Mayodia klippe and Hunli window, generated during folding of the SW-directed Tidding thrust and duplexing of Lesser Himalayan rocks (LHS) at depth. Reconstruction of two balanced cross-sections yields minimum shortening estimates of 70% (48 km) and 71% (133 km), respectively. The widths of the orogen for each transect are 21 km and 54 km, respectively. Our percent strain values are comparable to that of western Arunachal Himalaya, reflecting eastward-increasing strain due to counterclockwise rotation of India during convergence or along-strike variation in India's subduction angle. However, shortening magnitudes much less than that of the Sikkim (641 km), Bhutan (414-615 km), and western Arunachal Himalaya (515-775 km) could signal eastward increasing shortening of a unique Himalayan stratigraphic framework, evidenced by few GHC rocks, absence of Tethyan strata, and an extensive subduction mélange and forearc complex.

The addition of lidocaine to bupivacaine does not shorten the duration of spinal anesthesia

DEFF Research Database (Denmark)

Jacobsen, Jon; Husum, Bent; Staffeldt, Henrik

2011-01-01

The duration of spinal anesthesia with bupivacaine is often too long for day surgery. A recent study of patients presenting for transurethral surgery suggested that the addition of a small amount of lidocaine to intrathecal hyperbaric bupivacaine could shorten the duration of the sensory and motor...

The Spiritual Well-Being Scale: Psychometric Evaluation of the Shortened Version in Czech Adolescents

Czech Academy of Sciences Publication Activity Database

Maliňáková, K.; Kopčáková, J.; Kolarčik, P.; Madarasová Gecková, A.; Poláčková Šolcová, Iva; Hušek, V.; Klůzová Kračmárová, L.; Dubovská, E.; Kalman, M.; Půžová, Z.; van Dijk, J.P.; Tavel, P.

2017-01-01

Roč. 56, č. 2 (2017), s. 697-705 ISSN 0022-4197 Institutional support: RVO:68081740 Keywords : Shortened SWBS * Adolescents * Spirituality * Religiosity * Psychometric evaluation Subject RIV: DN - Health Impact of the Environment Quality OBOR OECD: Psychology (including human - machine relations) Impact factor: 0.873, year: 2016

Construction of Rate-Compatible LDPC Codes Utilizing Information Shortening and Parity Puncturing

Directory of Open Access Journals (Sweden)

Jones Christopher R

2005-01-01

Full Text Available This paper proposes a method for constructing rate-compatible low-density parity-check (LDPC codes. The construction considers the problem of optimizing a family of rate-compatible degree distributions as well as the placement of bipartite graph edges. A hybrid approach that combines information shortening and parity puncturing is proposed. Local graph conditioning techniques for the suppression of error floors are also included in the construction methodology.

Propagation of the Semidiurnal Internal Tide: Phase Velocity Versus Group Velocity

Science.gov (United States)

Zhao, Zhongxiang

2017-12-01

The superposition of two waves of slightly different wavelengths has long been used to illustrate the distinction between phase velocity and group velocity. The first-mode M2 and S2 internal tides exemplify such a two-wave model in the natural ocean. The M2 and S2 tidal frequencies are 1.932 and 2 cycles per day, respectively, and their superposition forms a spring-neap cycle in the semidiurnal band. The spring-neap cycle acts like a wave, with its frequency, wave number, and phase being the differences of the M2 and S2 internal tides. The spring-neap cycle and energy of the semidiurnal internal tide propagate at the group velocity. Long-range propagation of M2 and S2 internal tides in the North Pacific is observed by satellite altimetry. Along a 3,400 km beam spanning 24°-54°N, the M2 and S2 travel times are 10.9 and 11.2 days, respectively. For comparison, it takes the spring-neap cycle 21.1 days to travel over this distance. Spatial maps of the M2 phase velocity, the S2 phase velocity, and the group velocity are determined from phase gradients of the corresponding satellite observed internal tide fields. The observed phase and group velocities agree with theoretical values estimated using the World Ocean Atlas 2013 annual-mean ocean stratification.

Determination of velocity correction factors for real-time air velocity monitoring in underground mines.

Science.gov (United States)

Zhou, Lihong; Yuan, Liming; Thomas, Rick; Iannacchione, Anthony

2017-12-01

When there are installations of air velocity sensors in the mining industry for real-time airflow monitoring, a problem exists with how the monitored air velocity at a fixed location corresponds to the average air velocity, which is used to determine the volume flow rate of air in an entry with the cross-sectional area. Correction factors have been practically employed to convert a measured centerline air velocity to the average air velocity. However, studies on the recommended correction factors of the sensor-measured air velocity to the average air velocity at cross sections are still lacking. A comprehensive airflow measurement was made at the Safety Research Coal Mine, Bruceton, PA, using three measuring methods including single-point reading, moving traverse, and fixed-point traverse. The air velocity distribution at each measuring station was analyzed using an air velocity contour map generated with Surfer ® . The correction factors at each measuring station for both the centerline and the sensor location were calculated and are discussed.

CO2 laser pulse shortening by laser ablation of a metal target

International Nuclear Information System (INIS)

Donnelly, T.; Mazoyer, M.; Lynch, A.; O'Sullivan, G.; O'Reilly, F.; Dunne, P.; Cummins, T.

2012-01-01

A repeatable and flexible technique for pulse shortening of laser pulses has been applied to transversely excited atmospheric (TEA) CO 2 laser pulses. The technique involves focusing the laser output onto a highly reflective metal target so that plasma is formed, which then operates as a shutter due to strong laser absorption and scattering. Precise control of the focused laser intensity allows for timing of the shutter so that different temporal portions of the pulse can be reflected from the target surface before plasma formation occurs. This type of shutter enables one to reduce the pulse duration down to ∼2 ns and to remove the low power, long duration tails that are present in TEA CO 2 pulses. The transmitted energy is reduced as the pulse duration is decreased but the reflected power is ∼10 MW for all pulse durations. A simple laser heating model verifies that the pulse shortening depends directly on the plasma formation time, which in turn is dependent on the applied laser intensity. It is envisaged that this plasma shutter will be used as a tool for pulse shaping in the search for laser pulse conditions to optimize conversion efficiency from laser energy to useable extreme ultraviolet (EUV) radiation for EUV source development.

Shortened first-line TB treatment in Brazil: potential cost savings for patients and health services

NARCIS (Netherlands)

Trajman, Anete; Bastos, Mayara Lisboa; Belo, Marcia; Calaça, Janaína; Gaspar, Júlia; Dos Santos, Alexandre Martins; Dos Santos, Camila Martins; Brito, Raquel Trindade; Wells, William A.; Cobelens, Frank G.; Vassall, Anna; Gomez, Gabriela B.

2016-01-01

Shortened treatment regimens for tuberculosis are under development to improve treatment outcomes and reduce costs. We estimated potential savings from a societal perspective in Brazil following the introduction of a hypothetical four-month regimen for tuberculosis treatment. Data were gathered in

Uncertainty assessment of 3D instantaneous velocity model from stack velocities

Science.gov (United States)

Emanuele Maesano, Francesco; D'Ambrogi, Chiara

2015-04-01

3D modelling is a powerful tool that is experiencing increasing applications in data analysis and dissemination. At the same time the need of quantitative uncertainty evaluation is strongly requested in many aspects of the geological sciences and by the stakeholders. In many cases the starting point for 3D model building is the interpretation of seismic profiles that provide indirect information about the geology of the subsurface in the domain of time. The most problematic step in the 3D modelling construction is the conversion of the horizons and faults interpreted in time domain to the depth domain. In this step the dominant variable that could lead to significantly different results is the velocity. The knowledge of the subsurface velocities is related mainly to punctual data (sonic logs) that are often sparsely distributed in the areas covered by the seismic interpretation. The extrapolation of velocity information to wide extended horizons is thus a critical step to obtain a 3D model in depth that can be used for predictive purpose. In the EU-funded GeoMol Project, the availability of a dense network of seismic lines (confidentially provided by ENI S.p.A.) in the Central Po Plain, is paired with the presence of 136 well logs, but few of them have sonic logs and in some portion of the area the wells are very widely spaced. The depth conversion of the 3D model in time domain has been performed testing different strategies for the use and the interpolation of velocity data. The final model has been obtained using a 4 layer cake 3D instantaneous velocity model that considers both the initial velocity (v0) in every reference horizon and the gradient of velocity variation with depth (k). Using this method it is possible to consider the geological constraint given by the geometries of the horizons and the geo-statistical approach to the interpolation of velocities and gradient. Here we present an experiment based on the use of set of pseudo-wells obtained from the

Velocity Feedback Experiments

Directory of Open Access Journals (Sweden)

Chiu Choi

2017-02-01

Full Text Available Transient response such as ringing in a control system can be reduced or removed by velocity feedback. It is a useful control technique that should be covered in the relevant engineering laboratory courses. We developed velocity feedback experiments using two different low cost technologies, viz., operational amplifiers and microcontrollers. These experiments can be easily integrated into laboratory courses on feedback control systems or microcontroller applications. The intent of developing these experiments was to illustrate the ringing problem and to offer effective, low cost solutions for removing such problem. In this paper the pedagogical approach for these velocity feedback experiments was described. The advantages and disadvantages of the two different implementation of velocity feedback were discussed also.

The velocity of sound

International Nuclear Information System (INIS)

Beyer, R.T.

1985-01-01

The paper reviews the work carried out on the velocity of sound in liquid alkali metals. The experimental methods to determine the velocity measurements are described. Tables are presented of reported data on the velocity of sound in lithium, sodium, potassium, rubidium and caesium. A formula is given for alkali metals, in which the sound velocity is a function of shear viscosity, atomic mass and atomic volume. (U.K.)

Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions.

Science.gov (United States)

Chene, Gautier; Tchirkov, Andrei; Pierre-Eymard, Eleonore; Dauplat, Jacques; Raoelfils, Ines; Cayre, Anne; Watkin, Emmanuel; Vago, Philippe; Penault-Llorca, Frederique

2013-06-01

Genetic instability plays an important role in ovarian carcinogenesis. We investigated the level of telomere shortening and genomic instability in early and preinvasive stages of ovarian cancer, serous tubal intraepithelial carcinoma (STIC), and tubo-ovarian dysplasia (TOD). Fifty-one TOD from prophylactic salpingo-oophorectomies with BRCA1 or 2 mutation, 12 STICs, 53 tubo-ovarian high-grade serous carcinoma, and 36 noncancerous controls were laser capture microdissected from formalin-fixed, paraffin-embedded sections, analyzed by comparative genomic hybridization (array CGH) and for telomere length (using quantitative real-time PCR based on the Cawthon's method). TOD and STICs were defined by morphologic scores and immunohistochemical expressions of p53, Ki67, and γH2AX. TOD showed marked telomere shortening compared with noncancerous controls (P STICs had even shorter telomeres than TOD (P = 0.0008). Ovarian carcinoma had shorter telomeres than controls but longer than STICs and dysplasia. In TOD, telomeres were significantly shorter in those with BRCA1 mutation than in those with BRCA2 mutation (P = 0.005). In addition, γH2AX expression in TOD and STIC groups with short telomeres was significantly increased (P STICs. The total number of genetic alterations was the highest in ovarian cancers. These findings suggest that genetic instability occurs in early stages of ovarian tumorigenesis. STICs and noninvasive dysplasia are likely an important step in early serous ovarian neoplasia. ©2013 AACR

Synergistic shortening of the bleeding time by desmopressin and ethamsylate in patients with various constitutional bleeding disorders.

Science.gov (United States)

Kobrinsky, N L; Israels, E D; Bickis, M G

1991-01-01

Desmopressin and ethamsylate were evaluated for possible synergistic effects on the bleeding time. The drugs were administered individually and together to 12 patients with markedly prolonged bleeding times known to be relatively or absolutely unresponsive to desmopressin alone. The bleeding disorders studied included Glanzmann's thrombasthenia (one), other disorders of platelet function (four), pseudo-von Willebrand disease (one), and von Willebrand disease type I (three), type II (two), and type III (one). Desmopressin alone shortened the bleeding time from 23.9 +/- 1.5 to 19.5 +/- 2.3 min (p = 0.03). Ethamsylate alone was without effect. Desmopressin and ethamsylate together shortened the bleeding time to 11.2 +/- 1.4 min (p less than 0.01 compared to baseline, p = 0.02 compared to desmopressin alone). The combination was ineffective in three patients, with Glanzmann's thrombasthenia (one), and von Willebrand disease type I (one) and type III (one). Toxic effects of the drugs were not observed. Five patients received desmopressin and ethamsylate prior to dental work with mandibular block (one), heart surgery requiring cardiopulmonary bypass (two), and adenotonsillectomy surgery (two). Normal hemostasis was achieved in each case. A synergistic shortening of the bleeding time was observed with the combination of desmopressin and ethamsylate in a wide range of bleeding disorders.

Overexpression of the Large-Conductance, Ca2+-Activated K+ (BK) Channel Shortens Action Potential Duration in HL-1 Cardiomyocytes.

Science.gov (United States)

Stimers, Joseph R; Song, Li; Rusch, Nancy J; Rhee, Sung W

2015-01-01

Long QT syndrome is characterized by a prolongation of the interval between the Q wave and the T wave on the electrocardiogram. This abnormality reflects a prolongation of the ventricular action potential caused by a number of genetic mutations or a variety of drugs. Since effective treatments are unavailable, we explored the possibility of using cardiac expression of the large-conductance, Ca2+-activated K+ (BK) channel to shorten action potential duration (APD). We hypothesized that expression of the pore-forming α subunit of human BK channels (hBKα) in HL-1 cells would shorten action potential duration in this mouse atrial cell line. Expression of hBKα had minimal effects on expression levels of other ion channels with the exception of a small but significant reduction in Kv11.1. Patch-clamped hBKα expressing HL-1 cells exhibited an outward voltage- and Ca2+-sensitive K+ current, which was inhibited by the BK channel blocker iberiotoxin (100 nM). This BK current phenotype was not detected in untransfected HL-1 cells or in HL-1 null cells sham-transfected with an empty vector. Importantly, APD in hBKα-expressing HL-1 cells averaged 14.3 ± 2.8 ms (n = 10), which represented a 53% reduction in APD compared to HL-1 null cells lacking BKα expression. APD in the latter cells averaged 31.0 ± 5.1 ms (n = 13). The shortened APD in hBKα-expressing cells was restored to normal duration by 100 nM iberiotoxin, suggesting that a repolarizing K+ current attributed to BK channels accounted for action potential shortening. These findings provide initial proof-of-concept that the introduction of hBKα channels into a cardiac cell line can shorten APD, and raise the possibility that gene-based interventions to increase hBKα channels in cardiac cells may hold promise as a therapeutic strategy for long QT syndrome.

Nerve conduction velocity

Science.gov (United States)

... this page: //medlineplus.gov/ency/article/003927.htm Nerve conduction velocity To use the sharing features on this page, please enable JavaScript. Nerve conduction velocity (NCV) is a test to see ...

Matters which shorten the ozone layer; Substances qui appauvrissent la couche d'ozone

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-12-01

This document, proposed by the ministry of the national development and the environment, gives the list of the main texts relative to the matters which shorten the ozone layer and the evolution of the community regulations in this domain. The concerned matters are the Cfc and the HCFC production and use. (A.L.B.)

Determination of velocity correction factors for real-time air velocity monitoring in underground mines

OpenAIRE

Zhou, Lihong; Yuan, Liming; Thomas, Rick; Iannacchione, Anthony

2017-01-01

When there are installations of air velocity sensors in the mining industry for real-time airflow monitoring, a problem exists with how the monitored air velocity at a fixed location corresponds to the average air velocity, which is used to determine the volume flow rate of air in an entry with the cross-sectional area. Correction factors have been practically employed to convert a measured centerline air velocity to the average air velocity. However, studies on the recommended correction fac...

Visual Metaphors in Communication: Intertextual Semiosis and Déjà Vu in Print Advertising

Directory of Open Access Journals (Sweden)

Evripides Zantides

2017-01-01

Full Text Available Metaphor, as a concept in which a signified is applied to a signifier that is not literally applicable, does not only refer to speech or verbal language, but also to a wide use of practical applications in visual communication, particularly in advertising design and communication. The metaphorical rhetoric in advertisements is a common practice often used to attract the viewers’ attention, as well as enhance the persuasiveness of messages. From a cognitive perspective, semiosis in the process of visual metaphors in communication, is a complex subject with often a variety of subjective interpretations on behalf of the viewers. Intertextuality, as another form of metaphoric communication that depends on pre-existing texts (verbal or non-verbal, produces meanings that often deal with parody, sarcasm or irony. Additionally, they are also frequently characterised as anarchistic and provocative, because of the anti-advertising or anti-consumerism/social statements they make. The current study aims to present a literature review on how visual metaphors are defined in printa dvertising, and build on this to examine the notion of intertextuality as a form of déjà vu-metaphor that is popular in advertising and graphic communication. Semiotic analysis as a methodology is used on a purposive sample of print advertisements—including examples of logotypes as well—in order to categorize thematically the major typological references, in respect of intertextual advertising, as well as extract ideological conclusions. The results show that intertextuality in advertising draws its sources of meaning mainly from the Film industry, Art, Monuments and places, Literary texts and Graphic and Advertising itself, whilst, as far as logos is concerned, the source of meaning is purely linguistic. The study also shows that Intertextual visual metaphor semiosis has a variety of popular verbal or non-verbal references and depends on the socio-political context of the

[Effect of removable partial dentures restoration on oral health-related quality of life of patients with shortened dental arch].

Science.gov (United States)

Fu, Zhen-nan; Lin, Xue-feng

2013-11-01

To assess the effect of removable partial dentures (PRD) restoration on oral health-related quality of life (OHRQOL) of subjects with shortened dental arches (SDA) using the Chinese version of the Oral Health Impact Profile (OHIP-14). Consecutive patients with shortened dental arches were recruited from the Department of Prosthodontics, Foshan Chancheng Hospital of Stomatology. The Chinese version of OHIP-14 was administered to each subject before treatment and after treatment. The subjective outcomes of removable partial dentures therapy on SDA were collected and the pre- and post-treatment scores of the Chinese version of OHIP-14 were compared. After treatment, significant decrease in patients' total score of OHRQOL [before: 9 (6, 12) ; after: 4 (2.25, 6)] was detected, as well as physical pain subscale, physical disability subscale and handicap subscale; and the score of OHRQOL in function limitation subscale increased [before: 0(0,0); after: 2(1, 2)]. The main impacts of shortened dental arch with intact anterior region affecting patients' OHRQOL are physical disability.From a quality-of-life perspective, patients with SDA can perceive benefits from RPD.

Virtual unenhanced second generation dual-source CT of the liver: Is it time to discard the conventional unenhanced phase?

International Nuclear Information System (INIS)

Barrett, T.; Bowden, D.J.; Shaida, N.; Godfrey, E.M.; Taylor, A.; Lomas, D.J.; Shaw, A.S.

2012-01-01

Introduction: Dual-energy dual source CT can almost simultaneously image patients using two different tube potentials, allowing material decomposition and creation of ‘virtual unenhanced’ (VU) images from post-contrast series. Methods: 75 patients undergoing triple-phase liver CT examinations were imaged using a second generation dual-source CT machine with tube potentials 140/100 kVp. Post-processing VU series were derived from arterial and portal phases. Regions-of-interest from liver parenchyma and within fat (‘noise’ assessment) were drawn to compare VU series to conventional unenhanced (CU) series. Subjective analysis assessed image quality and the suitability of VU to replace CU series. Results: Mean Hounsfield unit (HU) values of liver were higher in the VU series: portal 51.9 (SD = 10.29), arterial 51.1 (SD = 10.05), compared to the CU series 49.2 (SD = 9.11); P < 0.001. However, Pearson's correlation of the VU and CU series remained excellent: 0.838 (portal), 0.831 (arterial). Bland–Altman plots also showed good agreement between both VU and the CU datasets. Noise measurements were significantly lower in both VU series (P < 0.001). For subjective analysis, image quality was rated as very good/excellent in 100% of CU images, 93.3% of portal VU and 88.7% of arterial VU series. Overall, portal VU and arterial VU images were acceptable replacements for the CU series in 97.4% and 96.1%, respectively. Post-processing was noted to create a number of artefacts in VU images – knowledge of these is essential for interpretation. Conclusions: Portal and arterial-derived VU images objectively correlate to CU images and demonstrate good image quality and acceptability. VU image sets could replace the conventional unenhanced images in the vast majority of cases, significantly reducing radiation dose.

Agresīvu datorspēļu spēlēšana saistībā ar pusaudžu un jauniešu agresiju

OpenAIRE

Vītols, Krists

2012-01-01

Bakalaura darba mērķis bija noskaidrot, vai pastāv nozīmīgas saistības starp agresīvu datorspēļu spēlēšanu, datorspēļu spēlēšanas biežumu un agresijas izpausmju līmeni pusaudžu un jauniešu vidū. Pētījumā tika aptaujāti 50 Latvijas skolu skolēni, vecumā no 12-16 gadiem. Pētījuma izlases tika viedotas pēc brīvprātības principa, pētījuma aptaujas tika izdalītas skolēnu klasēs. Pētījuma metodē tika izmantotas divas aptaujas: 1. “Datorspēļu aptauja” (Video Game Questionnaire, Anderson & ...

Telomere shortening is associated to TRF1 and PARP1 overexpression in Duchenne muscular dystrophy.

Science.gov (United States)

Aguennouz, M'Hammed; Vita, Gian Luca; Messina, Sonia; Cama, Annamaria; Lanzano, Natalia; Ciranni, Annamaria; Rodolico, Carmelo; Di Giorgio, Rosa Maria; Vita, Giuseppe

2011-12-01

Telomere shortening is thought to contribute to premature senescence of satellite cells in Duchenne muscular dystrophy (DMD) muscle. Telomeric repeat binding factor-1 (TRF1) and poly (ADP-ribose) polymerase-1 (PARP1) are proteins known to modulate telomerase reverse transcriptase (TERT) activity, which controls telomere elongation. Here we show that an age-dependent telomere shortening occurs in DMD muscles and is associated to overexpression of mRNA and protein levels of TRF1 and PARP1. TERT expression and activity are detectable in normal control muscles and they slightly increase in DMD. This is the first demonstration of TRF1 and PARP1 overexpression in DMD muscles. They can be directly involved in replicative senescence of satellite cells and/or in the pathogenetic cascade through a cross-talk with oxidative stress and inflammatory response. Modulation of these events by TRF1 or PARP1 inhibition might represent a novel strategy for treatment of DMD and other muscular dystrophies. Copyright © 2010 Elsevier Inc. All rights reserved.

Combined top-down and bottom-up climate change impact assessment for the hydrological system in the Vu Gia- Thu Bon River Basin.

Science.gov (United States)

Tra, Tran Van; Thinh, Nguyen Xuan; Greiving, Stefan

2018-07-15

Vu Gia- Thu Bon (VGTB) River Basin, located in the Central Coastal zone of Viet Nam currently faces water shortage. Climate change is expected to exacerbate the challenge. Therefore, there is a need to study the impacts of climate change on water shortage in the river basin. The study adopts a combined top-down and bottom-up climate change impact assessment to address the impacts of climate change on water shortage in the VGTB River Basin. A MIKE BASIN water balance model for the river basin was established to simulate the response of the hydrological system. Simulations were performed through parametrically varying temperature and precipitation to determine the vulnerability space of water shortage. General Circulation Models (GCMs) were then utilized to provide climate projections for the river basin. The output from GCMs was then mapped onto the vulnerability space determined earlier. In total, 9 out of 55 water demand nodes in the simulation are expected to face problematic conditions as future climate changes. Copyright © 2018 Elsevier B.V. All rights reserved.

Collective cell migration without proliferation: density determines cell velocity and wave velocity

Science.gov (United States)

Tlili, Sham; Gauquelin, Estelle; Li, Brigitte; Cardoso, Olivier; Ladoux, Benoît; Delanoë-Ayari, Hélène; Graner, François

2018-05-01

Collective cell migration contributes to embryogenesis, wound healing and tumour metastasis. Cell monolayer migration experiments help in understanding what determines the movement of cells far from the leading edge. Inhibiting cell proliferation limits cell density increase and prevents jamming; we observe long-duration migration and quantify space-time characteristics of the velocity profile over large length scales and time scales. Velocity waves propagate backwards and their frequency depends only on cell density at the moving front. Both cell average velocity and wave velocity increase linearly with the cell effective radius regardless of the distance to the front. Inhibiting lamellipodia decreases cell velocity while waves either disappear or have a lower frequency. Our model combines conservation laws, monolayer mechanical properties and a phenomenological coupling between strain and polarity: advancing cells pull on their followers, which then become polarized. With reasonable values of parameters, this model agrees with several of our experimental observations. Together, our experiments and model disantangle the respective contributions of active velocity and of proliferation in monolayer migration, explain how cells maintain their polarity far from the moving front, and highlight the importance of strain-polarity coupling and density in long-range information propagation.

Anesthetic Sevoflurane Causes Rho-Dependent Filopodial Shortening in Mouse Neurons.

Directory of Open Access Journals (Sweden)

Jeffrey H Zimering

Full Text Available Early postnatal anesthesia causes long-lasting learning and memory impairment in rodents, however, evidence for a specific neurotoxic effect on early synaptogenesis has not been demonstrated. Drebrin A is an actin binding protein whose localization in dendritic protrusions serves an important role in dendritic spine morphogenesis, and is a marker for early synaptogenesis. We therefore set out to investigate whether clinically-relevant concentrations of anesthetic sevoflurane, widely- used in infants and children, alters dendritic morphology in cultured fetal day 16 mouse hippocampal neurons. After 7 days in vitro, mouse hippocampal neurons were exposed to four hours of 3% sevoflurane in 95% air/5% CO2 or control condition (95% air/5% CO2. Neurons were fixed in 4% paraformaldehyde and stained with Alexa Fluor555-Phalloidin, and/or rabbit anti-mouse drebrin A/E antibodies which permitted subcellular localization of filamentous (F-actin and/or drebrin immunoreactivity, respectively. Sevoflurane caused acute significant length-shortening in filopodia and thin dendritic spines in days-in-vitro 7 neurons, an effect which was completely rescued by co-incubating neurons with ten micromolar concentrations of the selective Rho kinase inhibitor Y27632. Filopodia and thin spine recovered in length two days after sevoflurane exposure. Yet cluster-type filopodia (a precursor to synaptic filopodia were persistently significantly decreased in number on day-in-vitro 9, in part owing to preferential localization of drebrin immunoreactivity to dendritic shafts versus filopodial stalks. These data suggest that sevoflurane induces F-actin depolymerization leading to acute, reversible length-shortening in dendritic protrusions through a mechanism involving (in part activation of RhoA/Rho kinase signaling and impairs localization of drebrin A to filopodia required for early excitatory synapse formation.

Left ventricular systolic and diastolic function in hyperthyroidism

International Nuclear Information System (INIS)

Friedman, M.J.; Okada, R.D.; Ewy, G.A.; Hellman, D.J.

1982-01-01

In order to assess the effect of hyperthyroidism on systolic and diastolic function of the left ventricle, M-mode echocardiograms and systolic time intervals were obtained in 13 patients while they were clinically hyperthyroid and again when they were euthyroid following radioactive iodine therapy. Echocardiographic tracings of the septum and left ventricular posterior wall were digitized and analyzed to provide the maximum velocity of shortening and maximum velocity of lengthening. These velocities were normalized for left ventricular diastolic dimension. The left ventricular minor axis fractional shortening and the normalized maximum velocity of shortening were both increased during the hyperthyroid state. The normalized maximum velocity of lengthening, a measure of diastolic left ventricular function, was also increased during the hyperthyroid state when compared to the euthyroid state. The preejection period index and the preejection period/left ventricular ejection time ratio were lower when the patients were hyperthyroid than when they were euthyroid. These data confirm the increased inotropic state and demonstrated increased diastolic relaxation velocities of the hyperthyroid left ventricle

Consideration of some difficulties in migration velocity analysis; Migration velocity analysis no shomondai ni kansuru kento

Energy Technology Data Exchange (ETDEWEB)

Akama, K [Japan National Oil Corp., Tokyo (Japan). Technology Research Center; Matsuoka, T [Japan Petroleum Exploration Corp., Tokyo (Japan)

1997-10-22

Concerning migration velocity analysis in the seismic exploration method, two typical techniques, out of velocity analysis techniques using residual moveout in the CIP gather, are verified. Deregowski`s method uses pre-stacking deep-level migration records for velocity analysis to obtain velocities free of spatial inconsistency and not dependent on the velocity structure. This method is very like the conventional DMO velocity analysis method and is easy to understand intuitively. In this method, however, error is apt to be aggravated in the process of obtaining the depth-sector velocity from the time-RMS velocity. Al-Yahya`s method formulates the moveout residual in the CIP gather. This assumes horizontal stratification and a small residual velocity, however, and fails to guarantee convergence in the case of a steep structure or a grave model error. In the updating of the velocity model, in addition, it has to maintain required accuracy and, at the same time, incorporate smoothing to ensure not to deteriorate high convergence. 2 refs., 5 figs.

National Economic Development Procedures Manual. Recreation. Volume 3. A Case Study Application of the Contingent Valuation Method for Estimating Urban Recreation Use and Benefits

Science.gov (United States)

1990-11-01

rivers or lakes? YES NO YES NO Went fishing? YES NO YES NO Went skateboarding ? YES NO YES NO Visited outdoor scenic places? YES NO YES NO Used undeveloped...VN SN N SU VU Playground equipment VN SN N SU VU Concessions VN SN N SU VU Bicycle trails VN SN N SU VU Skateboard paths VN SN N SU VU Exercise/fitness

Psychometric evaluation of the shortened resilience scale among Alzheimer's caregivers.

Science.gov (United States)

Wilks, Scott E

2008-01-01

The purpose of this study was to evaluate psychometric properties of the shortened Resilience Scale (15-item version RS15) among a sample of Alzheimer's caregivers. Self-reported data were collected from 229 participants at 2 Alzheimer's caregiver conferences. RS15 principal axis factoring indicated a single-dimensional solution with all items loaded. Reliability was strong. Convergent validity for the RS15 was suggested through its correlations with stress, family support, and friend support. Odds ratios showed significant likelihoods of high resilience given low stress and high social support. The results confirmed the RS15 to be a psychometrically sound measure that can be used to appraise the efficacy of adaptability among Alzheimer's caregivers.

Velocity Segregation and Systematic Biases In Velocity Dispersion Estimates with the SPT-GMOS Spectroscopic Survey

Science.gov (United States)

Bayliss, Matthew. B.; Zengo, Kyle; Ruel, Jonathan; Benson, Bradford A.; Bleem, Lindsey E.; Bocquet, Sebastian; Bulbul, Esra; Brodwin, Mark; Capasso, Raffaella; Chiu, I.-non; McDonald, Michael; Rapetti, David; Saro, Alex; Stalder, Brian; Stark, Antony A.; Strazzullo, Veronica; Stubbs, Christopher W.; Zenteno, Alfredo

2017-03-01

The velocity distribution of galaxies in clusters is not universal; rather, galaxies are segregated according to their spectral type and relative luminosity. We examine the velocity distributions of different populations of galaxies within 89 Sunyaev Zel’dovich (SZ) selected galaxy clusters spanning 0.28GMOS spectroscopic survey, supplemented by additional published spectroscopy, resulting in a final spectroscopic sample of 4148 galaxy spectra—2868 cluster members. The velocity dispersion of star-forming cluster galaxies is 17 ± 4% greater than that of passive cluster galaxies, and the velocity dispersion of bright (m< {m}* -0.5) cluster galaxies is 11 ± 4% lower than the velocity dispersion of our total member population. We find good agreement with simulations regarding the shape of the relationship between the measured velocity dispersion and the fraction of passive versus star-forming galaxies used to measure it, but we find a small offset between this relationship as measured in data and simulations, which suggests that our dispersions are systematically low by as much as 3% relative to simulations. We argue that this offset could be interpreted as a measurement of the effective velocity bias that describes the ratio of our observed velocity dispersions and the intrinsic velocity dispersion of dark matter particles in a published simulation result. Measuring velocity bias in this way suggests that large spectroscopic surveys can improve dispersion-based mass-observable scaling relations for cosmology even in the face of velocity biases, by quantifying and ultimately calibrating them out.

Sodium Velocity Maps on Mercury

Science.gov (United States)

Potter, A. E.; Killen, R. M.

2011-01-01

The objective of the current work was to measure two-dimensional maps of sodium velocities on the Mercury surface and examine the maps for evidence of sources or sinks of sodium on the surface. The McMath-Pierce Solar Telescope and the Stellar Spectrograph were used to measure Mercury spectra that were sampled at 7 milliAngstrom intervals. Observations were made each day during the period October 5-9, 2010. The dawn terminator was in view during that time. The velocity shift of the centroid of the Mercury emission line was measured relative to the solar sodium Fraunhofer line corrected for radial velocity of the Earth. The difference between the observed and calculated velocity shift was taken to be the velocity vector of the sodium relative to Earth. For each position of the spectrograph slit, a line of velocities across the planet was measured. Then, the spectrograph slit was stepped over the surface of Mercury at 1 arc second intervals. The position of Mercury was stabilized by an adaptive optics system. The collection of lines were assembled into an images of surface reflection, sodium emission intensities, and Earthward velocities over the surface of Mercury. The velocity map shows patches of higher velocity in the southern hemisphere, suggesting the existence of sodium sources there. The peak earthward velocity occurs in the equatorial region, and extends to the terminator. Since this was a dawn terminator, this might be an indication of dawn evaporation of sodium. Leblanc et al. (2008) have published a velocity map that is similar.

Micro-Sugar-Snap and -Wire-Cut Cookie Baking with Trans- and Zero-Trans-Fat Shortenings

Science.gov (United States)

The effect of trans- and zero-trans-fat shortenings on cookie-baking performance was evaluated, using the two AACC micro-cookie-baking methods. Regardless of fat type, sugar-snap cookies made with a given flour were larger in diameter, smaller in height, and greater in weight loss during baking tha...

Water velocity meter

Science.gov (United States)

Roberts, C. W.; Smith, D. L.

1970-01-01

Simple, inexpensive drag sphere velocity meter with a zero to 6 ft/sec range measures steady-state flow. When combined with appropriate data acquisition system, it is suited to applications where large numbers of simultaneous measurements are needed for current mapping or velocity profile determination.

Deposition, clearance, and shortening of Kevlar para-aramid fibrils in acute, subchronic, and chronic inhalation studies in rats.

Science.gov (United States)

Kelly, D P; Merriman, E A; Kennedy, G L; Lee, K P

1993-10-01

The deposition and clearance of lung-deposited Kevlar para-aramid fibrils (subfibers) have been investigated as part of a subchronic and chronic inhalation toxicity testing program. Fibrils recovered from lung tissue in para-aramid-exposed Sprague-Dawley rats were microscopically counted and measured after exposures to airborne fibrils which were about 12 microns median length (ML) and < 0.3 micron median diameter. In each of three studies lung-recovered fibrils were progressively shorter with increasing residence time in the lungs. Twenty-eight days after a single 6-hr exposure at 400 respirable fibrils per cubic centimeter (f/cm3) the ML of recovered fibrils decreased to about 5 microns. Twenty-four months after a 3-week exposure to 25 or 400 f/cm3, fibrils reached about 2 microns ML. After 2 years of continuous exposure at 2.5, 25, or 100 f/cm3 or 1 year exposure plus 1 year recovery at 400 f/cm3, fibril ML approached 4 microns. In the 2-year study, the lung-fiber accumulation rate/exposure concentration was similar for the three highest concentrations and was about 3 x greater than that seen at 2.5 f/cm3, indicating that concentrations of about 25 f/cm3 or more may overwhelm clearance mechanisms. Time required for fibrils to be reduced to < 5 microns in the lung was markedly less at lower exposure concentration and shorter exposure time. The primary shortening mechanism is proposed to be long fibril cutting by enzymatic attack at fibril defects. However, length-selective fibril deposition and clearance may contribute to shortening in the first few days after exposure. The enzymatic cutting hypothesis is supported by measured increases in numbers of short fibers following cessation of exposures, continued shortening of the fibril length distribution up to 2 years following exposure, and in vitro fibril shortening after 3 months in a proteolytic enzyme preparation. The conclusion is that para-aramid fibrils are less durable in the lungs of rats than expected from

Evaluating the superiority of honey over silver sulphadiazine dressing in shortening healing duration of burn injury: an evidence-based case report

Directory of Open Access Journals (Sweden)

Sandy S. Sopandi

2013-12-01

Full Text Available Background: Burn injury is a global health problem associated with major morbidity and mortality. Honey has long been used in wound management due to its ability to accelerate healing rates and prevent infection. This study is conducted to evaluate the efficacy of honey dressing in shortening healing duration of burn injury compared to silver sulphadiazine (SSD.Methods: A PubMed and Proquest database search was conducted to identify relevant studies. The studies were then appraised and ranked based on their validity, importance, and level of evidence.Results: The two studies appraised in this paper supported the supremacy of honey against SSD in shortening healing duration. However, the individual quality of studies involved was low.Conclusion: Honey is an alternative treatment in shortening burn wound healing duration. Further studies are needed to support clinical application of this conclusion. (Med J Indones. 2013;22:243-7. doi: 10.13181/mji.v22i4.608 Keywords: Burn injury, healing duration, honey, silver sulfadiazine

Eocene to Miocene Out-of-Sequence Deformation in the Eastern Tibetan Plateau: Insights From Shortening Structures in the Sichuan Basin

Science.gov (United States)

Tian, Yuntao; Kohn, Barry P.; Qiu, Nansheng; Yuan, Yusong; Hu, Shengbiao; Gleadow, Andrew J. W.; Zhang, Peizhen

2018-02-01

A distinctive NNE trending belt of shortening structures dominates the topography and deformation of the eastern Sichuan Basin, 300 km east of the Tibetan Plateau. Debate continues as to whether the structures resulted from Cenozoic eastward growth of the Tibetan Plateau. A low-temperature thermochronology (AFT and AHe) data set from four deep boreholes and adjacent outcrops intersecting a branch of the shortening structures indicates distinctive differential cooling at 35-28 Ma across the structure, where stratigraphy has been offset vertically by 0.8-1.3 km. This result forms the first quantitative evidence for the existence of a late Eocene-Oligocene phase of shortening in the eastern Sichuan Basin, synchronous with the early phase of eastward growth and extrusion of the Tibetan Plateau. Further, a compilation of regional Cenozoic structures reveals a Miocene retreat of deformation from the foreland basin to the hinterland areas. Such a tectonic reorganization indicates that Eocene to Miocene deformation in the eastern Tibetan Plateau is out-of-sequence and was probably triggered by enhanced erosion in the eastern Tibetan Plateau.

Influence of lateral slab edge distance on plate velocity, trench velocity, and subduction partitioning

NARCIS (Netherlands)

Schellart, W. P.; Stegman, D. R.; Farrington, R. J.; Moresi, L.

2011-01-01

Subduction of oceanic lithosphere occurs through both trenchward subducting plate motion and trench retreat. We investigate how subducting plate velocity, trench velocity and the partitioning of these two velocity components vary for individual subduction zone segments as a function of proximity to

The addition of lidocaine to bupivacaine does not shorten the duration of spinal anesthesia

DEFF Research Database (Denmark)

Jacobsen, Jon; Husum, Bent; Staffeldt, Henrik

2011-01-01

The duration of spinal anesthesia with bupivacaine is often too long for day surgery. A recent study of patients presenting for transurethral surgery suggested that the addition of a small amount of lidocaine to intrathecal hyperbaric bupivacaine could shorten the duration of the sensory and moto...... blocks. In this prospective, randomized double-blind study we investigated these findings in patients undergoing unilateral knee arthroscopy....

Diabetes mellitus as a cause of life span shortening in locally exposed rats

International Nuclear Information System (INIS)

Vershinina, S.F.; Markochev, A.B.

1992-01-01

A study was made of the development of remote radiation pathology of pancreas in male rats after local irradiation of abdomen with doses of 5, 10 (two fractions of 5 Gy at a 30-day interval) and 15 Gy (three fractions of 5 Gy at a 30-day interval). The clinical and morphological estimates show the dose-dependent development of diabetes mellitus and 1.8-fold shortening of the life span, as compared to biological control

Gelatinized wheat starch influences crystallization behaviour and structure of roll-in shortenings in laminated bakery products.

Science.gov (United States)

Mattice, Kristin D; Marangoni, Alejandro G

2018-03-15

One hydrogenated and one non-hydrogenated shortening were baked with isolated components of a croissant matrix, including crystalline wheat starch, gelatinized wheat starch, gluten, and formed gluten network. The impact of the matrix components on fat crystallization was analyzed for polymorphism using powder X-ray diffraction, solid fat content by pulsed nuclear magnetic resonance and thermal behaviour by differential scanning calorimetry. When compared to results obtained from croissants prepared with the respective shortenings, samples containing gelatinized wheat starch displayed notably similar results: polymorphic conversion, from the β' to β form over storage, and visually broader peaks in the melting endotherms indicating a greater temperature was required to completely melt all of the fat. All other component mixtures behaved similar to the respective fats in bulk. The measured rate of crystallization was greater in samples containing gelatinized wheat starch, indicating that the gelatinized starch could act as a nucleation site to speed crystallization. Copyright © 2017 Elsevier Ltd. All rights reserved.

Kinetic therapy reduces complications and shortens hospital stay in patients with cardiogenic shock - a retrospective analysis.

Science.gov (United States)

Simonis, Gregor; Flemming, Kerstin; Ziegs, Enrico; Haacke, Katrin; Rauwolf, Thomas; Strasser, Ruth H

2007-03-01

Kinetic therapy (KT) has been shown to reduce complications and to shorten hospital stay in trauma patients. Data in non-surgical patients are inconclusive, and kinetic therapy has not been tested in patients with cardiogenic shock. The present analysis compares KT with standard care in patients with cardiogenic shock. A retrospective analysis of 133 patients with cardiogenic shock admitted to 1 academic heart center was performed. Patients with standard care (SC, turning every 2 h by the staff) were compared with kinetic therapy (KT, using oscillating air-flotation beds). 68 patients with KT were compared with 65 patients with SC. Length of ventilator therapy was 11 days in KT and 18 days in SC (p=0.048). The mortality was comparable in both groups. Pneumonia occurred in 14 patients in KT and 39 patients in SC (ppatients treated with kinetic therapy. The use of KT shortens hospital stay and reduces rates of pneumonia and pressure ulcers as compared to SC.

Limiting values for the RBE of fission neutrons at low doses for life shortening in mice

International Nuclear Information System (INIS)

Storer, J.B.; Mitchell, T.J.

1984-01-01

The authors have analyzed recently published data on the effects of low doses of fission neutrons on the mean survival times of mice. The analysis for single-dose exposures was confined to doses of 20 rad or less, while for fractionated exposures only total doses of 80 rad or less were considered. They fitted the data to the frequently used power function model: life shortening = βD/sup γ/, where D is the radiation dose. They show that, at low doses per fraction, either the effects are not additive or the dose-effect curve for single exposures cannot show a greater negative curvature than about the 0.9 power of dose. Analysis of the data for γ rays showed that an exponent of 1.0 gave an acceptable fit. They conclude that at neutron doses of 20 rad or less the RBE for life shortening is constant and ranges from 13 to 22 depending on mouse strain and sex

[The concentration of growth factors in patients with inherent and acquired shortenings of limbs bones].

Science.gov (United States)

Strogov, M V; Luneva, S N; Novikov, K I

2013-04-01

The article deals with the results of study of level of growth factors in blood serum of patients with inherent and post-traumatic shortenings of limbs' bones. The detection in blood serum the level of epidermal growth factor insulin-like growth factor I and angiopoetins is proposed to monitor in given patients the reparative bone formation.

Crustal thickness and velocity structure across the Moroccan Atlas from long offset wide-angle reflection seismic data: The SIMA experiment

Science.gov (United States)

Ayarza, P.; Carbonell, R.; Teixell, A.; Palomeras, I.; Martí, D.; Kchikach, A.; Harnafi, M.; Levander, A.; Gallart, J.; Arboleya, M. L.; Alcalde, J.; Fernández, M.; Charroud, M.; Amrhar, M.

2014-05-01

The crustal structure and topography of the Moho boundary beneath the Atlas Mountains of Morocco has been constrained by a controlled source, wide-angle seismic reflection transect: the SIMA experiment. This paper presents the first results of this project, consisting of an almost 700 km long, high-resolution seismic profile acquired from the Sahara craton across the High and the Middle Atlas and the Rif Mountains. The interpretation of this seismic data set is based on forward modeling by raytracing, and has resulted in a detailed crustal structure and velocity model for the Atlas Mountains. Results indicate that the High Atlas features a moderate crustal thickness, with the Moho located at a minimum depth of 35 km to the S and at around 31 km to the N, in the Middle Atlas. Upper crustal shortening is resolved at depth through a crustal root where the Saharan crust underthrusts the northern Moroccan crust. This feature defines a lower crust imbrication that, locally, places the Moho boundary at ˜40-41 km depth in the northern part of the High Atlas. The P-wave velocity model is characterized by relatively low velocities, mostly in the lower crust and upper mantle, when compared to other active orogens and continental regions. These low deep crustal velocities together with other geophysical observables such as conductivity estimates derived from MT measurements, moderate Bouguer gravity anomaly, high heat flow, and surface exposures of recent alkaline volcanism lead to a model where partial melts are currently emplaced at deep crustal levels and in the upper mantle. The resulting model supports the existence of a mantle upwelling as mechanism that would contribute significantly to sustain the High Atlas topography. However, the detailed Moho geometry deduced in this work should lead to a revision of the exact geometry and position of this mantle feature and will require new modeling efforts.

Computed Tomography Based Three-dimensional Measurements of Spine Shortening Distance After Posterior Three-column Osteotomies for the Treatment of Severe and Stiff Scoliosis.

Science.gov (United States)

Li, Xue-Shi; Huang, Zi-Fang; Deng, Yao-Long; Fan, Heng-Wei; Sui, Wen-Yuan; Wang, Chong-Wen; Yang, Jun-Lin

2017-07-15

Retrospective study. This study is to measure and analyze the changes of three-dimensional (3D) distances of spinal column and spinal canal at the three-column osteotomy sites and address their clinical and neurologic significance. Three-column osteotomies were developed to treat severe and stiff spine deformities with insufficient understanding on the safe limit of spine shortening and the relationship between the shortening distance of the spinal column and that of the spinal canal. Records of 52 continuous patients with severe and stiff scoliosis treated with three-column spine osteotomies at our institution from July 2013 to June 2015 were reviewed. The preoperative spinal cord function classification were type A in 31 cases, type B in 10 cases, and type C in 11 cases. The types of osteotomies carried out were extended pedicle subtraction osteotomy in nine patients and posterior vertebral column resection in 43 patients. Multimodality neuromonitoring strategies were adopted intraoperatively. 3D pre- and postoperative spine models were reconstructed from the computed tomography (CT) scans. The distances of convex and concave spinal column and the spinal canal shortening were measured and analyzed. The spinal column shortening distance (SCSD) measured on the 3D models (27.8 mm) were statistically shorter than those measured intraoperatively (32.8 mm) (P column strut graft than in those with bone-on-bone fusion (P column cannot represent that of the central spinal canal in patients with severe scoliosis. The spinal column shortening procedure in appropriately selected patient groups with bone-on-bone fusion is a viable option with the CCSD being significantly shorter than the convex SCSD. 4.

The critical ionization velocity

International Nuclear Information System (INIS)

Raadu, M.A.

1980-06-01

The critical ionization velocity effect was first proposed in the context of space plasmas. This effect occurs for a neutral gas moving through a magnetized plasma and leads to rapid ionization and braking of the relative motion when a marginal velocity, 'the critical velocity', is exceeded. Laboratory experiments have clearly established the significance of the critical velocity and have provided evidence for an underlying mechanism which relies on the combined action of electron impact ionization and a collective plasma interaction heating electrons. There is experimental support for such a mechanism based on the heating of electrons by the modified two-stream instability as part of a feedback process. Several applications to space plasmas have been proposed and the possibility of space experiments has been discussed. (author)

Compatibility of selected plant-based shortening as lard substitute: microstructure, polymorphic forms and textural properties; Compatibilidad de grasas vegetales formuladas como sustitutas de la manteca: microestructura, formas polimórficas y propiedades texturales.

Energy Technology Data Exchange (ETDEWEB)

Yanty, N.A.M.; Marikkar, J.M.N.; Miskandar, M.S.; Bockstaele, F. Van; Dewettinck, K.; Nusantoro, B.P.

2017-07-01

A study was carried out to determine the compatibility of three plant-based shortening mixtures to lard shortening (LD) in terms of microstructure, polymorphic forms, and textural properties. The shortenings of binary, ternary, and quaternary fat mixtures were prepared according to a standard procedure by blending mee fat (MF) with palm stearin (PS) in a 99:1 (w/w) ratio; avocado fat (Avo) with PS and cocoa butter (CB) in a 84:7:9 (w/w) ratio; palm oil (PO) with PS, soybean oil (SBO) and CB in a 38:5:52:5 (w/w) ratio, respectively. The triacylglycerol composition, polymorphic forms, crystal morphology, and textural properties of the shortening were evaluated. This study found that all three plant-based shortenings and LD shortening were similar with respect to their consistency, hardness and compression and adhesiveness values. However, all plant-based shortening was found to be dissimilar to LD shortening with respect to microstructure. [Spanish] Se realizó un estudio para determinar la compatibilidad de tres shortenings vegetales con manteca (LD) en términos de microestructura, formas polimórficas y propiedades texturales. Los shortenings de las mezclas de grasas binarias, ternarias y cuaternarias se prepararon de acuerdo con un procedimiento estándar mezclando la grasa de mee (MF) con estearina de palma (PS) en una relación de 99:1 (p/p); grasa de aguacate (Avo) con PS y manteca de cacao (CB) en la relación 84:7:9 (p/p); aceite de palma (PO) con PS, aceite de soja (SBO) y CB en la relación 38:5:52:5 (p/p), respectivamente. Se evaluó la composición de triacilgliceridos, las formas polimórficas, la morfología cristalina y las propiedades texturales de las grasas. Este estudio encontró que los tres shortenings a base de plantas y LD fueron similares con respecto a su consistencia, dureza y valores de compresión y adhesividad. Sin embargo, se encontró que todas las grasas a base de plantas eran distintas al shortening de LD con respecto a la

Superimposed extension and shortening in the southern Salinas Basin and La Panza Range, California: A guide to Neogene deformation in the Salinian block of the central California Coast Ranges

Science.gov (United States)

Colgan, Joseph P.; McPhee, Darcy K.; McDougall, Kristin; Hourigan, Jeremy K.

2013-01-01

We synthesized data from geologic maps, wells, seismic-reflection profiles, potential-field interpretations, and low-temperature thermochronology to refine our understanding of late Cenozoic extension and shortening in the Salinian block of the central California Coast Ranges. Data from the La Panza Range and southern Salinas Basin document early to middle Miocene extension, followed by Pliocene and younger shortening after a period of little deformation in the late Miocene. Extension took place on high-angle normal faults that accommodated ∼2% strain at the scale of the ∼50-km-wide Salinian block (oriented perpendicular to the San Andreas fault). Shortening was accommodated by new reverse faults, reactivation of older normal faults, and strike-slip faulting that resulted in a map-view change in the width of the Salinian block. The overall magnitude of shortening was ∼10% strain, roughly 4–5 times greater than the amount of extension. The timing and magnitude of deformation in our study area are comparable to that documented in other Salinian block basins, and we suggest that the entire block deformed in a similar manner over a similar time span. The timing and relative magnitude of extension and shortening may be understood in the context of central Coast Range tectonic boundary conditions linked to rotation of the western Transverse Ranges at the south end of the Salinian block. Older models for Coast Range shortening based on balanced fault-bend fold-style cross sections are a poor approximation of Salinian block deformation, and may lead to mechanically improbable fault geometries that overestimate the amount of shortening.

Examples of Vector Velocity Imaging

DEFF Research Database (Denmark)

Hansen, Peter M.; Pedersen, Mads M.; Hansen, Kristoffer L.

2011-01-01

To measure blood flow velocity in vessels with conventional ultrasound, the velocity is estimated along the direction of the emitted ultrasound wave. It is therefore impossible to obtain accurate information on blood flow velocity and direction, when the angle between blood flow and ultrasound wa...

The SCEC Unified Community Velocity Model (UCVM) Software Framework for Distributing and Querying Seismic Velocity Models

Science.gov (United States)

Maechling, P. J.; Taborda, R.; Callaghan, S.; Shaw, J. H.; Plesch, A.; Olsen, K. B.; Jordan, T. H.; Goulet, C. A.

2017-12-01

Crustal seismic velocity models and datasets play a key role in regional three-dimensional numerical earthquake ground-motion simulation, full waveform tomography, modern physics-based probabilistic earthquake hazard analysis, as well as in other related fields including geophysics, seismology, and earthquake engineering. The standard material properties provided by a seismic velocity model are P- and S-wave velocities and density for any arbitrary point within the geographic volume for which the model is defined. Many seismic velocity models and datasets are constructed by synthesizing information from multiple sources and the resulting models are delivered to users in multiple file formats, such as text files, binary files, HDF-5 files, structured and unstructured grids, and through computer applications that allow for interactive querying of material properties. The Southern California Earthquake Center (SCEC) has developed the Unified Community Velocity Model (UCVM) software framework to facilitate the registration and distribution of existing and future seismic velocity models to the SCEC community. The UCVM software framework is designed to provide a standard query interface to multiple, alternative velocity models, even if the underlying velocity models are defined in different formats or use different geographic projections. The UCVM framework provides a comprehensive set of open-source tools for querying seismic velocity model properties, combining regional 3D models and 1D background models, visualizing 3D models, and generating computational models in the form of regular grids or unstructured meshes that can be used as inputs for ground-motion simulations. The UCVM framework helps researchers compare seismic velocity models and build equivalent simulation meshes from alternative velocity models. These capabilities enable researchers to evaluate the impact of alternative velocity models in ground-motion simulations and seismic hazard analysis applications

Mastication in subjects with extremely shortened dental arches rehabilitated with removable partial dentures.

Science.gov (United States)

Arce-Tumbay, Jackelyn; Sanchez-Ayala, Alfonso; Sotto-Maior, Bruno Salles; Senna, Plinio Mendes; Campanha, Nara Hellen

2011-01-01

Mastication was evaluated in subjects presenting extremely shortened dental arches (ESDAs) rehabilitated with mandibular free-end removable partial dentures (RPDs). Subjects were divided into four groups (n = 10): those with a complete dentition, those with ESDAs, and those with ESDAs who were rehabilitated with an RPD, who were evaluated both with and without their prostheses. Mastication was measured through masticatory performance, time, and ability. RPD wearers showed higher masticatory performance (P mastication in ESDA subjects but without achieving normal mastication levels.

Spinal column shortening for tethered cord syndrome associated with myelomeningocele, lumbosacral lipoma, and lipomyelomeningocele in children and young adults.

Science.gov (United States)

Aldave, Guillermo; Hansen, Daniel; Hwang, Steven W; Moreno, Amee; Briceño, Valentina; Jea, Andrew

2017-06-01

OBJECTIVE Tethered cord syndrome is the clinical manifestation of an abnormal stretch on the spinal cord, presumably causing mechanical injury, a compromised blood supply, and altered spinal cord metabolism. Tethered cord release is the standard treatment for tethered cord syndrome. However, direct untethering of the spinal cord carries potential risks, such as new neurological deficits from spinal cord injury, a CSF leak from opening the dura, and retethering of the spinal cord from normal scar formation after surgery. To avoid these risks, the authors applied spinal column shortening to children and transitional adults with primary and secondary tethered cord syndrome and report treatment outcomes. The authors' aim with this study was to determine the safety and efficacy of spinal column shortening for tethered cord syndrome by analyzing their experience with this surgical technique. METHODS The authors retrospectively reviewed the demographic and procedural data of children and young adults who had undergone spinal column shortening for primary or secondary tethered cord syndrome. RESULTS Seven patients with tethered cord syndrome caused by myelomeningocele, lipomyelomeningocele, and transitional spinal lipoma were treated with spinal column shortening. One patient with less than 24 months of follow-up was excluded from further analysis. There were 3 males and 4 females; the average age at the time was surgery was 16 years (range 8-30 years). Clinical presentations for our patients included pain (in 5 patients), weakness (in 4 patients), and bowel/bladder dysfunction (in 4 patients). Spinal column osteotomy was most commonly performed at the L-1 level, with fusion between T-12 and L-2 using a pedicle screw-rod construct. Pedicle subtraction osteotomy was performed in 6 patients, and vertebral column resection was performed in 1 patient. The average follow-up period was 31 months (range 26-37 months). Computed tomography-based radiographic outcomes showed solid

Relationship between throwing velocity, muscle power, and bar velocity during bench press in elite handball players.

Science.gov (United States)

Marques, Mario C; van den Tilaar, Roland; Vescovi, Jason D; Gonzalez-Badillo, Juan Jose

2007-12-01

The purpose of this study was to examine the relationship between ball-throwing velocity during a 3-step running throw and dynamic strength, power, and bar velocity during a concentric-only bench-press exercise in team-handball players. Fourteen elite senior male team-handball players volunteered to participate. Each volunteer had power and bar velocity measured during a concentric-only bench-press test with 26, 36, and 46 kg, as well as having 1-repetition-maximum (1-RMBP) strength determined. Ball-throwing velocity was evaluated with a standard 3-step running throw using a radar gun. Ball-throwing velocity was related to the absolute load lifted during the 1-RMBP (r = .637, P = .014), peak power using 36 kg (r = .586, P = .028) and 46 kg (r = .582, P = .029), and peak bar velocity using 26 kg (r = .563, P = .036) and 36 kg (r = .625, P = .017). The results indicate that throwing velocity of elite team-handball players is related to maximal dynamic strength, peak power, and peak bar velocity. Thus, a training regimen designed to improve ball-throwing velocity in elite male team-handball players should include exercises that are aimed at increasing both strength and power in the upper body.

Rapid bioassay-guided screening of toxic substances in vegetable oils that shorten the life of SHRSP rats

Directory of Open Access Journals (Sweden)

Lewandowski Paul

2010-02-01

Full Text Available Abstract It has been consistently reported that vegetable oils including canola oil have a life shortening effect in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP and this toxic effect is not due to the fatty acid composition of the oil. Although it is possible that the phytosterol content or type of phytosterol present in vegetable oils may play some role in the life shortening effect observed in SHRSP rats this is still not completely resolved. Furthermore supercritical CO2 fractionation of canola oil with subsequent testing in SHRSP rats identified safe and toxic fractions however, the compounds responsible for life shortening effect were not characterised. The conventional approach to screen toxic substances in oils using rats takes more than six months and involves large number of animals. In this article we describe how rapid bioassay-guided screening could be used to identify toxic substances derived from vegetable oils and/or processed foods fortified with vegetable oils. The technique incorporates sequential fractionation of oils/processed foods and subsequent treatment of human cell lines that can be used in place of animal studies to determine cytotoxicity of the fractions with structural elucidation of compounds of interest determined via HPLC-MS and GC-MS. The rapid bioassay-guided screening proposed would require two weeks to test multiple fractions from oils, compared with six months if animal experiments were used to screen toxic effects. Fractionation of oil before bio-assay enhances the effectiveness of the detection of active compounds as fractionation increases the relative concentration of minor components.

Estimating the Wet-Rock P-Wave Velocity from the Dry-Rock P-Wave Velocity for Pyroclastic Rocks

Science.gov (United States)

Kahraman, Sair; Fener, Mustafa; Kilic, Cumhur Ozcan

2017-07-01

Seismic methods are widely used for the geotechnical investigations in volcanic areas or for the determination of the engineering properties of pyroclastic rocks in laboratory. Therefore, developing a relation between the wet- and dry-rock P-wave velocities will be helpful for engineers when evaluating the formation characteristics of pyroclastic rocks. To investigate the predictability of the wet-rock P-wave velocity from the dry-rock P-wave velocity for pyroclastic rocks P-wave velocity measurements were conducted on 27 different pyroclastic rocks. In addition, dry-rock S-wave velocity measurements were conducted. The test results were modeled using Gassmann's and Wood's theories and it was seen that estimates for saturated P-wave velocity from the theories fit well measured data. For samples having values of less and greater than 20%, practical equations were derived for reliably estimating wet-rock P-wave velocity as function of dry-rock P-wave velocity.

Shortened version of the work ability index to identify workers at risk of long-term sickness absence

NARCIS (Netherlands)

Schouten, Lianne S.; Bultmann, Ute; Heymans, Martijn W.; Joling, Catelijne I.; Twisk, Jos W. R.; Roelen, Corne A. M.

2016-01-01

Background: The Work Ability Index (WAI) identifies non-sicklisted workers at risk of future long-term sickness absence (LTSA). The WAI is a complicated instrument and inconvenient for use in large-scale surveys. We investigated whether shortened versions of the WAI identify non-sicklisted workers

Field Testing of an In-well Point Velocity Probe for the Rapid Characterization of Groundwater Velocity

Science.gov (United States)

Osorno, T.; Devlin, J. F.

2017-12-01

Reliable estimates of groundwater velocity is essential in order to best implement in-situ monitoring and remediation technologies. The In-well Point Velocity Probe (IWPVP) is an inexpensive, reusable tool developed for rapid measurement of groundwater velocity at the centimeter-scale in monitoring wells. IWPVP measurements of groundwater speed are based on a small-scale tracer test conducted as ambient groundwater passes through the well screen and the body of the probe. Horizontal flow direction can be determined from the difference in tracer mass passing detectors placed in four funnel-and-channel pathways through the probe, arranged in a cross pattern. The design viability of the IWPVP was confirmed using a two-dimensional numerical model in Comsol Multiphysics, followed by a series of laboratory tank experiments in which IWPVP measurements were calibrated to quantify seepage velocities in both fine and medium sand. Lab results showed that the IWPVP was capable of measuring the seepage velocity in less than 20 minutes per test, when the seepage velocity was in the range of 0.5 to 4.0 m/d. Further, the IWPVP estimated the groundwater speed with a precision of ± 7%, and an accuracy of ± 14%, on average. The horizontal flow direction was determined with an accuracy of ± 15°, on average. Recently, a pilot field test of the IWPVP was conducted in the Borden aquifer, C.F.B. Borden, Ontario, Canada. A total of approximately 44 IWPVP tests were conducted within two 2-inch groundwater monitoring wells comprising a 5 ft. section of #8 commercial well screen. Again, all tests were completed in under 20 minutes. The velocities estimated from IWPVP data were compared to 21 Point Velocity Probe (PVP) tests, as well as Darcy-based estimates of groundwater velocity. Preliminary data analysis shows strong agreement between the IWPVP and PVP estimates of groundwater velocity. Further, both the IWPVP and PVP estimates of groundwater velocity appear to be reasonable when

Knowledge, perceptions and clinical application of the shortened dental arch concept among Malaysian government dentists.

Science.gov (United States)

Kasim, Siti Kamilah Mohd; Razak, Ishak Abdul; Yusof, Zamros Yuzadi Mohd

2018-02-01

To assess the knowledge and perceptions of Malaysian government dentists regarding the shortened dental arch (SDA) concept and its application in clinical practice. The SDA concept refers to a specific type of dentition with intact anterior teeth and a reduction in posterior occlusal pairs. Dentists' knowledge and perceptions of the SDA concept can influence its application in clinical practice. A self-administered questionnaire on the SDA concept was distributed to 326 government dentists in the states of Selangor and Kuala Lumpur, Malaysia. The data were analysed using SPSS version 22 software. The response rate was 84.0%. The majority of respondents had good knowledge on five of six knowledge items and good attitudes towards 10 of 17 perception items. However, only one-fifth (20.4%) reported having applied the SDA concept in the clinic. A larger number of participants who graduated locally than who graduated abroad perceived that patients 5 years of work experience perceived that the SDA concept enables simpler treatment planning (P concept, it is not widely applied in the clinic. Concerted efforts in SDA training of dentists are needed to help to shorten denture waiting lists and reduce costs. © 2017 FDI World Dental Federation.

Incorporated fish oil fatty acids prevent action potential shortening induced by circulating fish oil fatty acids

Directory of Open Access Journals (Sweden)

Hester M Den Ruijter

2010-11-01

Full Text Available Increased consumption of fatty fish, rich in omega-3 polyunsaturated fatty acids (3-PUFAs reduces the severity and number of arrhythmias. Long term 3-PUFA-intake modulates the activity of several cardiac ion channels leading to cardiac action potential shortening. Circulating 3-PUFAs in the bloodstream and incorporated 3-PUFAs in the cardiac membrane have a different mechanism to shorten the action potential. It is, however, unknown whether circulating 3-PUFAs in the bloodstream enhance or diminish the effects of incorporated 3-PUFAs. In the present study, we address this issue. Rabbits were fed a diet rich in fish oil (3 or sunflower oil (9, as control for 3 weeks. Ventricular myocytes were isolated by enzymatic dissociation and action potentials were measured using the perforated patch clamp technique in the absence and presence of acutely administered 3-PUFAs. Plasma of 3 fed rabbits contained more free eicosapentaenoic acid (EPA and isolated myocytes of 3 fed rabbits contained higher amounts of both EPA and docosahexaenoic acid (DHA in their sarcolemma compared to control. In the absence of acutely administered fatty acids, 3 myocytes had a shorter action potential with a more negative plateau than 9 myocytes. In the 9 myocytes, but not in the 3 myocytes, acute administration of a mixture of EPA+DHA shortened the action potential significantly. From these data we conclude that incorporated 3-PUFAs into the sarcolemma and acutely administered 3 fatty acids do not have a cumulative effect on action potential duration and morphology. As a consequence, patients with a high cardiac 3-PUFA status will probably not benefit from short term 3 supplementation as an antiarrhythmic therapy.

Velocity Dispersions Across Bulge Types

International Nuclear Information System (INIS)

Fabricius, Maximilian; Bender, Ralf; Hopp, Ulrich; Saglia, Roberto; Drory, Niv; Fisher, David

2010-01-01

We present first results from a long-slit spectroscopic survey of bulge kinematics in local spiral galaxies. Our optical spectra were obtained at the Hobby-Eberly Telescope with the LRS spectrograph and have a velocity resolution of 45 km/s (σ*), which allows us to resolve the velocity dispersions in the bulge regions of most objects in our sample. We find that the velocity dispersion profiles in morphological classical bulge galaxies are always centrally peaked while the velocity dispersion of morphologically disk-like bulges stays relatively flat towards the center--once strongly barred galaxies are discarded.

Rotational foot placement specifies the lever arm of the ground reaction force during the push-off phase of walking initiation.

Science.gov (United States)

Erdemir, Ahmet; Piazza, Stephen J

2002-06-01

The lever arm of the ground reaction force (GRF) about the talocrural joint axis is a functionally important indicator of the nature of foot loading. Walking initiation experiments (ten subjects; age, 23-29 years) were completed to demonstrate that rotational foot placement is a possible strategy to specify the lever arm. Externally-rotated foot placement resulted in larger lever arms during push-off. A computer simulation of push-off revealed that a decreased lever arm reduces the plantarflexion moment necessary to maintain a constant forward velocity, while increasing the required plantarflexion velocity. Shortening of the foot thus diminishes the muscular force demand but also requires high muscle fiber shortening velocities that may limit the force generating capacity of plantar flexors. Decreased plantar flexion moment and slow walking previously noted in partial-foot amputees may result from shortened lever arms in this manner.

Estimation of vector velocity

DEFF Research Database (Denmark)

2000-01-01

Using a pulsed ultrasound field, the two-dimensional velocity vector can be determined with the invention. The method uses a transversally modulated ultrasound field for probing the moving medium under investigation. A modified autocorrelation approach is used in the velocity estimation. The new...

Analysis of photosynthate translocation velocity and measurement of weighted average velocity in transporting pathway of crops

International Nuclear Information System (INIS)

Ge Cailin; Luo Shishi; Gong Jian; Zhang Hao; Ma Fei

1996-08-01

The translocation profile pattern of 14 C-photosynthate along the transporting pathway in crops were monitored by pulse-labelling a mature leaf with 14 CO 2 . The progressive spreading of translocation profile pattern along the sheath or stem indicates that the translocation of photosynthate along the sheath or stem proceed with a range of velocities rather than with just a single velocity. The method for measuring the weighted average velocity of photosynthate translocation along the sheath or stem was established in living crops. The weighted average velocity and the maximum velocity of photosynthate translocation along the sheath in rice and maize were measured actually. (4 figs., 3 tabs.)

Action Potential Shortening and Impairment of Cardiac Function by Ablation of Slc26a6.

Science.gov (United States)

Sirish, Padmini; Ledford, Hannah A; Timofeyev, Valeriy; Thai, Phung N; Ren, Lu; Kim, Hyo Jeong; Park, Seojin; Lee, Jeong Han; Dai, Gu; Moshref, Maryam; Sihn, Choong-Ryoul; Chen, Wei Chun; Timofeyeva, Maria Valeryevna; Jian, Zhong; Shimkunas, Rafael; Izu, Leighton T; Chiamvimonvat, Nipavan; Chen-Izu, Ye; Yamoah, Ebenezer N; Zhang, Xiao-Dong

2017-10-01

Intracellular pH (pH i ) is critical to cardiac excitation and contraction; uncompensated changes in pH i impair cardiac function and trigger arrhythmia. Several ion transporters participate in cardiac pH i regulation. Our previous studies identified several isoforms of a solute carrier Slc26a6 to be highly expressed in cardiomyocytes. We show that Slc26a6 mediates electrogenic Cl - /HCO 3 - exchange activities in cardiomyocytes, suggesting the potential role of Slc26a6 in regulation of not only pH i , but also cardiac excitability. To test the mechanistic role of Slc26a6 in the heart, we took advantage of Slc26a6 knockout ( Slc26a6 -/ - ) mice using both in vivo and in vitro analyses. Consistent with our prediction of its electrogenic activities, ablation of Slc26a6 results in action potential shortening. There are reduced Ca 2+ transient and sarcoplasmic reticulum Ca 2+ load, together with decreased sarcomere shortening in Slc26a6 -/ - cardiomyocytes. These abnormalities translate into reduced fractional shortening and cardiac contractility at the in vivo level. Additionally, pH i is elevated in Slc26a6 -/ - cardiomyocytes with slower recovery kinetics from intracellular alkalization, consistent with the Cl - /HCO 3 - exchange activities of Slc26a6. Moreover, Slc26a6 -/ - mice show evidence of sinus bradycardia and fragmented QRS complex, supporting the critical role of Slc26a6 in cardiac conduction system. Our study provides mechanistic insights into Slc26a6, a unique cardiac electrogenic Cl - /HCO 3 - transporter in ventricular myocytes, linking the critical roles of Slc26a6 in regulation of pH i , excitability, and contractility. pH i is a critical regulator of other membrane and contractile proteins. Future studies are needed to investigate possible changes in these proteins in Slc26a6 -/ - mice. © 2017 American Heart Association, Inc.

Correlation of right atrial appendage velocity with left atrial appendage velocity and brain natriuretic Peptide.

Science.gov (United States)

Kim, Bu-Kyung; Heo, Jung-Ho; Lee, Jae-Woo; Kim, Hyun-Soo; Choi, Byung-Joo; Cha, Tae-Joon

2012-03-01

Left atrial appendage (LAA) anatomy and function have been well characterized both in healthy and diseased people, whereas relatively little attention has been focused on the right atrial appendage (RAA). We sought to evaluate RAA flow velocity and to compare these parameters with LAA indices and with a study of biomarkers, such as brain natriuretic peptide, among patients with sinus rhythm (SR) and atrial fibrillation (AF). In a series of 79 consecutive patients referred for transesophageal echocardiography, 43 patients (23 with AF and 20 controls) were evaluated. AF was associated with a decrease in flow velocity for both LAA and RAA [LAA velocity-SR vs. AF: 61 ± 22 vs. 29 ± 18 m/sec (p vs. AF: 46 ± 20 vs. 19 ± 8 m/sec (p brain natriuretic peptide (BNP). AF was associated with decreased RAA and LAA flow velocities. RAA velocity was found to be positively correlated with LAA velocity and negatively correlated with BNP. The plasma BNP concentration may serve as a determinant of LAA and RAA functions.

Increased Risk Proneness or Social Withdrawal? The Effects of Shortened Life Expectancy on the Expression of Rescue Behavior in Workers of the ant Formica cinerea (Hymenoptera: Formicidae).

Science.gov (United States)

Miler, Krzysztof; Symonowicz, Beata; Godzińska, Ewa J

2017-01-01

In social insects behavioral consequences of shortened life expectancy include, among others, increased risk proneness and social withdrawal. We investigated the impact of experimental shortening of life expectancy of foragers of the ant Formica cinerea achieved by their exposure to carbon dioxide on the expression of rescue behavior, risky pro-social behavior, tested by means of two bioassays during which a single worker (rescuer) was confronted with a nestmate (victim) attacked by a predator (antlion larva capture bioassay) or immobilized by an artificial snare (entrapment bioassay). Efficacy of carbon dioxide poisoning in shortening life expectancy was confirmed by the analysis of ant mortality. Rescue behavior observed during behavioral tests involved digging around the victim, transport of the sand covering the victim, pulling the limbs/antennae/mandibles of the victim, direct attack on the antlion (in antlion larva capture tests), and snare biting (in entrapment tests). The rate of occurrence of rescue behavior was lower in ants with shortened life expectancy, but that effect was significant only in the case of the entrapment bioassay. Similarly, only in the case of the entrapment bioassay ants with shortened life expectancy displayed rescue behavior after a longer latency and devoted less time to that behavior than ants from the control groups. Our results demonstrated that in ant workers shortened life expectancy may lead to reduced propensity for rescue behavior, most probably as an element of the social withdrawal syndrome that had already been described in several studies on behavior of moribund ants and honeybees.

Experimental investigation of impulse response shortening for low-complexity MLSE of a 112-Gbit/s PAM-4 transceiver

NARCIS (Netherlands)

van der Heide, S.; Eiselt, N.; Griesser, H.; Olmos, J. J.V.; Tafur Monroy, I.; Okonkwo, C.

2016-01-01

An optimized channel shortening method for reduced complexity MLSE detection enables the compensation of severe inter-symbol interference. Experimental investigations demonstrate the benefit on the performance for a severely bandwidth limited 112-Gbit/s PAM-4 transmission system with residual

Experimental investigation of impulse response shortening for low-complexity MLSE of a 112-Gbit/s PAM-4 transceiver

DEFF Research Database (Denmark)

Van Der Heide, Sjoerd; Eiselt, Nicklas; Griesser, Helmut

2016-01-01

An optimized channel shortening method for reduced complexity MLSE detection enables the compensation of severe inter-symbol interference. Experimental investigations demonstrate the benefit on the performance for a severely bandwidth limited 112-Gbit/s PAM-4 transmission system with residual chr...

Enhanced Corticospinal Excitability and Volitional Drive in Response to Shortening and Lengthening Strength Training and Changes Following Detraining

NARCIS (Netherlands)

Tallent, Jamie; Goodall, Stuart; Gibbon, Karl C.; Hortobagyi, Tibor; Howatson, Glyn

2017-01-01

There is a limited understanding of the neurological adaptations responsible for changes in strength following shortening and lengthening resistance training and subsequent detraining. The aim of the study was to investigate differences in corticospinal and spinal responses to resistance training of

Radiation-induced life shortening in neonatally thymectomized germ-free mice

International Nuclear Information System (INIS)

Anderson, R.E.; Howarth, J.L.; Troup, G.M.

1980-01-01

Radiation in sufficient amounts is carcinogenic, immunosuppressive, and results in a reduced life span. Similar consequences follow neonatal thymectomy (nTx) in some strains of rodents. The tumorigenic effects of irradiation appear to be partly mediated via suppression of the thymus-dependent portion of the immune response. Our purpose was to determine whether a similar relationship exists for radiation-induced accelerated aging. Female germ-free Charles River mice had neonatal or sham thymectomies within 24 hours of birth. Half of each group was exposed to 700 rads at 6 weeks of age. When mice with histologically malignant tumors were excluded, the combined life-shortening effects of nTx and irradiation were less pronounced than the sum of the individual effects. This suggests that some of the decreased longevity associated with irradiation may be mediated by T-cell injury

The application of shortened upper leaf mutant in barley breeding

International Nuclear Information System (INIS)

Jin Hua

2004-01-01

The shortened upper leaf mutant was induced from Fuji Nigo by γ-ray irradiation. Fuji Nigo, the mutant, cross-cut F 1 , F 2 and back-cross F 1 , F 2 were used to analyze mutant heredity by comparative study. The yield, chlorophyll content, light intensity, dry matter of mutant were investigated. The results showed that (1) the mutant character was controlled by a couple of nuclear genes which were partial dominance; (2) the transmittance of the mutant colony was better than that of Fuji Nigo and bottom dry matter was much more than that of Fuji Nigo; (3) under the condition of high fertilizer and high plant population , the yield of mutant was higher than that of Fuji Nigo; (4) the content of chlorophyll a in the mutant was higher than that in Fuji Nigo

Development of advanced concept for shortening construction period of ABWR plant (part 2)

International Nuclear Information System (INIS)

Fujita, Tomohiro; Satoh, Takashi

2003-01-01

The construction of the first building fully applying SC structure, which is indispensable for shortening construction period of ABWR plants (21.5 months from the first concrete work to fuel loading), has been started since August 2002 in Japan. Before the construction start, a pre-construction test with some actual size SC panels was carried out to confirm the SC modular construction method. The outline of the design and the construction of the first full-SC building and the results of the pre-construction test are reported. (author)

A comparison of effects of lard and hydrogenated vegetable shortening on the development of high-fat diet-induced obesity in rats.

Science.gov (United States)

Kubant, R; Poon, A N; Sánchez-Hernández, D; Domenichiello, A F; Huot, P S P; Pannia, E; Cho, C E; Hunschede, S; Bazinet, R P; Anderson, G H

2015-12-14

Obesity is associated with increased consumption and preference for dietary fat. Experimental models of fat-induced obesity use either lard or vegetable shortening. Yet, there are no direct comparisons of these commonly used fat sources, or the influence of their fatty acid composition, on the development of diet-induced obesity. To compare the effects of lard and hydrogenated vegetable-shortening diets, which differ in their fatty acid composition, on weight gain and the development of obesity and insulin resistance in rats. Male Wistar rats were fed ad libitum for 14 weeks high-fat diets containing either (1) high vegetable fat (HVF, 60 kcal% from vegetable shortening) or (2) high lard fat (HLF, 60 kcal% from lard). Rats fed normal-fat (NF, 16 kcal% from vegetable shortening) diet served as control. Body weight, food intake, adipose tissue mass, serum 25[OH]D3, glucose, insulin and fatty acid composition of diets were measured. Rats fed either of the two high-fat diets had higher energy intake, weight gain and fat accretion than rats fed normal-fat diet. However, rats fed the HLF diet consumed more calories and gained more weight and body fat with greater increases of 32% in total (158.5±8.2 vs 120.2±6.6 g, P<0.05), 30% in visceral (104.4±5.2 vs 80.3±4.2 g, P<0.05) and 36% in subcutaneous fat mass (54.1±3.6 vs 39.9±3.1 g, P<0.05), compared with rats fed the HVF diet. Higher visceral adiposity was positively correlated with serum insulin (r=0.376, P<0.05) and homeostatic model assessment insulin resistance (r=0.391, P<0.05). We conclude that lard-based high-fat diets accentuate the increase in weight gain and the development of obesity and insulin resistance more than hydrogenated vegetable-shortening diets. These results further point to the importance of standardizing fatty acid composition and type of fat used in determining outcomes of consuming high-fat diets.

A Comparison of Ulnar Shortening Osteotomy Alone Versus Combined Arthroscopic Triangular Fibrocartilage Complex Debridement and Ulnar Shortening Osteotomy for Ulnar Impaction Syndrome

Science.gov (United States)

Song, Hyun Seok

2011-01-01

Background This study compared the results of patients treated for ulnar impaction syndrome using an ulnar shortening osteotomy (USO) alone with those treated with combined arthroscopic debridement and USO. Methods The results of 27 wrists were reviewed retrospectively. They were divided into three groups: group A (USO alone, 10 cases), group B (combined arthroscopic debridement and USO, 9 cases), and group C (arthroscopic triangular fibrocartilage complex [TFCC] debridement alone, 8 cases). The wrist function was evaluated using the modified Mayo wrist score, disabilities of the arm, shoulder and hand (DASH) score and Chun and Palmer grading system. Results The modified Mayo wrist score in groups A, B, and C was 74.5 ± 8.9, 73.9 ± 11.6, and 61.3 ± 10.2, respectively (p 0.05). Conclusions Both USO alone and combined arthroscopic TFCC debridement with USO improved the wrist function and reduced the level of pain in the patients treated for ulnar impaction syndrome. USO alone may be the preferred method of treatment in patients if the torn flap of TFCC is not unstable. PMID:21909465

Online Wavelet Complementary velocity Estimator.

Science.gov (United States)

Righettini, Paolo; Strada, Roberto; KhademOlama, Ehsan; Valilou, Shirin

2018-02-01

In this paper, we have proposed a new online Wavelet Complementary velocity Estimator (WCE) over position and acceleration data gathered from an electro hydraulic servo shaking table. This is a batch estimator type that is based on the wavelet filter banks which extract the high and low resolution of data. The proposed complementary estimator combines these two resolutions of velocities which acquired from numerical differentiation and integration of the position and acceleration sensors by considering a fixed moving horizon window as input to wavelet filter. Because of using wavelet filters, it can be implemented in a parallel procedure. By this method the numerical velocity is estimated without having high noise of differentiators, integration drifting bias and with less delay which is suitable for active vibration control in high precision Mechatronics systems by Direct Velocity Feedback (DVF) methods. This method allows us to make velocity sensors with less mechanically moving parts which makes it suitable for fast miniature structures. We have compared this method with Kalman and Butterworth filters over stability, delay and benchmarked them by their long time velocity integration for getting back the initial position data. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

On whistler-mode group velocity

International Nuclear Information System (INIS)

Sazhin, S.S.

1986-01-01

An analytical of the group velocity of whistler-mode waves propagating parallel to the magnetic field in a hot anisotropic plasma is presented. Some simple approximate formulae, which can be used for the magnetospheric applications, are derived. These formulae can predict some properties of this group velocity which were not previously recognized or were obtained by numerical methods. In particular, it is pointed out that the anisotropy tends to compensate for the influence of the electron temperature on the value of the group velocity when the wave frequency is well below the electron gyrofrequency. It is predicted, that under conditions at frequencies near the electron gyrofrequency, this velocity tends towards zero

Fatty acid composition and contents of trans monounsaturated fatty acids in frying fats, and in margarines and shortenings marketed in Denmark

DEFF Research Database (Denmark)

Ovesen, L.; Leth, Torben; Hansen, K.

1998-01-01

This study examined trans monounsaturated fatty acid contents in all margarines and shortenings marketed in Denmark, and in frying fats used by the fast-food restaurants Burger King and McDonald's. Trans C-18:1 content was 4.1 +/- 3.8% (g per 100 g fatty acids) in hard margarines, significantly...... of trans long-chain fatty acids. Both fast-food frying fats contained large amounts of trans C-18:1, 21.9 +/- 2.9% in Burger King and 16.6 +/- 0.4% in McDonald's. In Denmark the per capita supply of trans C-18:1 from margarines and shortenings and frying fats has decreased steadily during recent years...

Agonist muscle adaptation accompanied by antagonist muscle atrophy in the hindlimb of mice following stretch-shortening contraction training.

Science.gov (United States)

Rader, Erik P; Naimo, Marshall A; Ensey, James; Baker, Brent A

2017-02-02

The vast majority of dynamometer-based animal models for investigation of the response to chronic muscle contraction exposure has been limited to analysis of isometric, lengthening, or shortening contractions in isolation. An exception to this has been the utilization of a rat model to study stretch-shortening contractions (SSCs), a sequence of consecutive isometric, lengthening, and shortening contractions common during daily activity and resistance-type exercise. However, the availability of diverse genetic strains of rats is limited. Therefore, the purpose of the present study was to develop a dynamometer-based SSC training protocol to induce increased muscle mass and performance in plantarflexor muscles of mice. Young (3 months old) C57BL/6 mice were subjected to 1 month of plantarflexion SSC training. Hindlimb muscles were analyzed for muscle mass, quantitative morphology, myogenesis/myopathy relevant gene expression, and fiber type distribution. The main aim of the research was achieved when training induced a 2-fold increase in plantarflexion peak torque output and a 19% increase in muscle mass for the agonist plantaris (PLT) muscle. In establishing this model, several outcomes emerged which raised the value of the model past that of being a mere recapitulation of the rat model. An increase in the number of muscle fibers per transverse muscle section accounted for the PLT muscle mass gain while the antagonist tibialis anterior (TA) muscle atrophied by 30% with preferential atrophy of type IIb and IIx fibers. These alterations were accompanied by distinct gene expression profiles. The findings confirm the development of a stretch-shortening contraction training model for the PLT muscle of mice and demonstrate that increased cross-sectional fiber number can occur following high-intensity SSC training. Furthermore, the TA muscle atrophy provides direct evidence for the concept of muscle imbalance in phasic non-weight bearing muscles, a concept largely

Leucocyte Telomere Shortening in relation to Newly Diagnosed Type 2 Diabetic Patients with Depression

Directory of Open Access Journals (Sweden)

Zhelong Liu

2014-01-01

Full Text Available The goal of this study is to investigate the association between oxidative stress and telomere length shortening in the comorbid depression and diabetes. Therefore, 71 patients with newly diagnosed type 2 diabetes (T2D and 52 subjects with normal glycemic level (control, Ctrl were enrolled. Depressive status was identified with the Depression Subscale of Hospital Anxiety and Depression Scale (HADS-D. Leukocyte telomere length ratio (T/S ratio was determined with quantitative PCR. Oxidative stress status was evaluated with 8-hydroxy-desoxyguanosine (8-OHdG assay kit. Some other biochemical blood testing was also performed. The data showed that T2D patients had higher proportion of depression evaluated by the HADS-D (x2=4.196, P=0.041. T/S ratio was significantly negatively correlated with 8-OHdG, HADS-D, age, HbA1c, FPG, and HOMA-IR. In addition, HADS-D was significantly positively correlated with HbA1c, FPG, HOMA-IR, and 8-OHdG. Both HADS-D and 8-OHdG were the major independent predictors for T/S ratio. This study indicates that oxidative stress contributes to both telomere length shortening and depression development in newly diagnosed type 2 diabetic patients, while in depression status, some other mechanisms besides oxidative stress may also affect the telomere length.

Characteristic wave velocities in spherical electromagnetic cloaks

International Nuclear Information System (INIS)

Yaghjian, A D; Maci, S; Martini, E

2009-01-01

We investigate the characteristic wave velocities in spherical electromagnetic cloaks, namely, phase, ray, group and energy-transport velocities. After deriving explicit expressions for the phase and ray velocities (the latter defined as the phase velocity along the direction of the Poynting vector), special attention is given to the determination of group and energy-transport velocities, because a cursory application of conventional formulae for local group and energy-transport velocities can lead to a discrepancy between these velocities if the permittivity and permeability dyadics are not equal over a frequency range about the center frequency. In contrast, a general theorem can be proven from Maxwell's equations that the local group and energy-transport velocities are equal in linear, lossless, frequency dispersive, source-free bianisotropic material. This apparent paradox is explained by showing that the local fields of the spherical cloak uncouple into an E wave and an H wave, each with its own group and energy-transport velocities, and that the group and energy-transport velocities of either the E wave or the H wave are equal and thus satisfy the general theorem.

Stuck in gear: age-related loss of variable gearing in skeletal muscle.

Science.gov (United States)

Holt, Natalie C; Danos, Nicole; Roberts, Thomas J; Azizi, Emanuel

2016-04-01

Skeletal muscles power a broad diversity of animal movements, despite only being able to produce high forces over a limited range of velocities. Pennate muscles use a range of gear ratios, the ratio of muscle shortening velocity to fiber shortening velocity, to partially circumvent these force-velocity constraints. Muscles operate with a high gear ratio at low forces; fibers rotate to greater angles of pennation, enhancing velocity but compromising force. At higher forces, muscles operate with a lower gear ratio; fibers rotate little so limiting muscle shortening velocity, but helping to preserve force. This ability to shift gears is thought to be due to the interplay of contractile force and connective tissue constraints. In order to test this hypothesis, gear ratios were determined in the medial gastrocnemius muscles of both healthy young rats, and old rats where the interaction between contractile and connective tissue properties was assumed to be disrupted. Muscle fiber and aponeurosis stiffness increased with age (PGear ratio decreased with increasing force in young (Pgearing is lost in old muscle. These findings support the hypothesis that variable gearing results from the interaction between contractile and connective tissues and suggest novel explanations for the decline in muscle performance with age. © 2016. Published by The Company of Biologists Ltd.

Optimal shortening of uniform covering arrays.

Directory of Open Access Journals (Sweden)

Jose Torres-Jimenez

Full Text Available Software test suites based on the concept of interaction testing are very useful for testing software components in an economical way. Test suites of this kind may be created using mathematical objects called covering arrays. A covering array, denoted by CA(N; t, k, v, is an N × k array over [Formula: see text] with the property that every N × t sub-array covers all t-tuples of [Formula: see text] at least once. Covering arrays can be used to test systems in which failures occur as a result of interactions among components or subsystems. They are often used in areas such as hardware Trojan detection, software testing, and network design. Because system testing is expensive, it is critical to reduce the amount of testing required. This paper addresses the Optimal Shortening of Covering ARrays (OSCAR problem, an optimization problem whose objective is to construct, from an existing covering array matrix of uniform level, an array with dimensions of (N - δ × (k - Δ such that the number of missing t-tuples is minimized. Two applications of the OSCAR problem are (a to produce smaller covering arrays from larger ones and (b to obtain quasi-covering arrays (covering arrays in which the number of missing t-tuples is small to be used as input to a meta-heuristic algorithm that produces covering arrays. In addition, it is proven that the OSCAR problem is NP-complete, and twelve different algorithms are proposed to solve it. An experiment was performed on 62 problem instances, and the results demonstrate the effectiveness of solving the OSCAR problem to facilitate the construction of new covering arrays.

Southern high-velocity stars

International Nuclear Information System (INIS)

Augensen, H.J.; Buscombe, W.

1978-01-01

Using the model of the Galaxy presented by Eggen, Lynden-Bell and Sandage (1962), plane galactic orbits have been calculated for 800 southern high-velocity stars which possess parallax, proper motion, and radial velocity data. The stars with trigonometric parallaxes were selected from Buscombe and Morris (1958), supplemented by more recent spectroscopic data. Photometric parallaxes from infrared color indices were used for bright red giants studied by Eggen (1970), and for red dwarfs for which Rodgers and Eggen (1974) determined radial velocities. A color-color diagram based on published values of (U-B) and (B-V) for most of these stars is shown. (Auth.)

Modified Feynman ratchet with velocity-dependent fluctuations

Directory of Open Access Journals (Sweden)

Jack Denur

2004-03-01

Full Text Available Abstract: The randomness of Brownian motion at thermodynamic equilibrium can be spontaneously broken by velocity-dependence of fluctuations, i.e., by dependence of values or probability distributions of fluctuating properties on Brownian-motional velocity. Such randomness-breaking can spontaneously obtain via interaction between Brownian-motional Doppler effects --- which manifest the required velocity-dependence --- and system geometrical asymmetry. A non random walk is thereby spontaneously superposed on Brownian motion, resulting in a systematic net drift velocity despite thermodynamic equilibrium. The time evolution of this systematic net drift velocity --- and of velocity probability density, force, and power output --- is derived for a velocity-dependent modification of Feynman's ratchet. We show that said spontaneous randomness-breaking, and consequent systematic net drift velocity, imply: bias from the Maxwellian of the system's velocity probability density, the force that tends to accelerate it, and its power output. Maximization, especially of power output, is discussed. Uncompensated decreases in total entropy, challenging the second law of thermodynamics, are thereby implied.

Velocity distribution of fragments of catastrophic impacts

Science.gov (United States)

Takagi, Yasuhiko; Kato, Manabu; Mizutani, Hitoshi

1992-01-01

Three dimensional velocities of fragments produced by laboratory impact experiments were measured for basalts and pyrophyllites. The velocity distribution of fragments obtained shows that the velocity range of the major fragments is rather narrow, at most within a factor of 3 and that no clear dependence of velocity on the fragment mass is observed. The NonDimensional Impact Stress (NDIS) defined by Mizutani et al. (1990) is found to be an appropriate scaling parameter to describe the overall fragment velocity as well as the antipodal velocity.

Effect of Shortened Heat Treatment on the Hardness and Microstructure of 320.0 Aluminium Alloy

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Pezda J.

2014-06-01

Full Text Available Improvement of Al-Si alloys properties in scope of classic method is connected with change of Si precipitations morphology through: using modification of the alloy, maintaining suitable temperature of overheating and pouring process, as well as perfection of heat treatment methods. Growing requirements of the market make it necessary to search after such procedures, which would quickly deliver positive results with simultaneous consideration of economic aspects. Presented in the paper shortened heat treatment with soaking of the alloy at temperature near temperature of solidus could be assumed as the method in the above mentioned understanding of the problem. Such treatment consists in soaking of the alloy to temperature of solutioning, keeping in such temperature, and next, quick quenching in water (20 °C followed by artificial ageing. Temperature ranges of solutioning and ageing treatments implemented in the adopted testing plan were based on analysis of recorded curves from the ATD method. Obtained results relate to dependencies and spatial diagrams describing effect of parameters of the solutioning and ageing treatments on HB hardness of the investigated alloy and change of its microstructure. Performed shortened heat treatment results in precipitation hardening of the investigated 320.0 alloy, what according to expectations produces increased hardness of the material.

Improvement of visual debugging tool. Shortening the elapsed time for getting data and adding new functions to compare/combine a set of visualized data

International Nuclear Information System (INIS)

Matsuda, Katsuyuki; Takemiya, Hiroshi

2001-03-01

The visual debugging tool 'vdebug' has been improved, which was designed for the debugging of programs for scientific computing. Improved were the following two points; (1) shortening the elapsed time required for getting appropriate data to visualize; (2) adding new functions which enable to compare and/or combine a set of visualized data originated from two or more different programs. As for shortening elapsed time for getting data, with the improved version of 'vdebug', we could achieve the following results; over hundred times shortening the elapsed time with dbx, pdbx of SX-4 and over ten times with ndb of SR2201. As for the new functions to compare/combine visualized data, it was confirmed that we could easily checked the consistency between the computational results obtained in each calculational steps on two different computers: SP and ONYX. In this report, we illustrate how the tool 'vdebug' has been improved with an example. (author)

Velocity spectrum for the Iranian plateau

Science.gov (United States)

Bastami, Morteza; Soghrat, M. R.

2018-01-01

Peak ground acceleration (PGA) and spectral acceleration values have been proposed in most building codes/guidelines, unlike spectral velocity (SV) and peak ground velocity (PGV). Recent studies have demonstrated the importance of spectral velocity and peak ground velocity in the design of long period structures (e.g., pipelines, tunnels, tanks, and high-rise buildings) and evaluation of seismic vulnerability in underground structures. The current study was undertaken to develop a velocity spectrum and for estimation of PGV. In order to determine these parameters, 398 three-component accelerograms recorded by the Building and Housing Research Center (BHRC) were used. The moment magnitude (Mw) in the selected database was 4.1 to 7.3, and the events occurred after 1977. In the database, the average shear-wave velocity at 0 to 30 m in depth (Vs30) was available for only 217 records; thus, the site class for the remaining was estimated using empirical methods. Because of the importance of the velocity spectrum at low frequencies, the signal-to-noise ratio of 2 was chosen for determination of the low and high frequency to include a wider range of frequency content. This value can produce conservative results. After estimation of the shape of the velocity design spectrum, the PGV was also estimated for the region under study by finding the correlation between PGV and spectral acceleration at the period of 1 s.

Shortened version of the work ability index to identify workers at risk of long-term sickness absence.

Science.gov (United States)

Schouten, Lianne S; Bültmann, Ute; Heymans, Martijn W; Joling, Catelijne I; Twisk, Jos W R; Roelen, Corné A M

2016-04-01

The Work Ability Index (WAI) identifies non-sicklisted workers at risk of future long-term sickness absence (LTSA). The WAI is a complicated instrument and inconvenient for use in large-scale surveys. We investigated whether shortened versions of the WAI identify non-sicklisted workers at risk of LTSA. Prospective study including two samples of non-sicklisted workers participating in occupational health checks between 2010 and 2012. A heterogeneous development sample (N= 2899) was used to estimate logistic regression coefficients for the complete WAI, a shortened WAI version without the list of diseases, and single-item Work Ability Score (WAS). These three instruments were calibrated for predictions of different (≥2, ≥4 and ≥6 weeks) LTSA durations in a validation sample of non-sicklisted workers (N= 3049) employed at a steel mill, differentiating between manual (N= 1710) and non-manual (N= 1339) workers. The discriminative ability was investigated by receiver operating characteristic analysis. All three instruments under-predicted the LTSA risks in both manual and non-manual workers. The complete WAI discriminated between individuals at high and low risk of LTSA ≥2, ≥4 and ≥6 weeks in manual and non-manual workers. Risk predictions and discrimination by the shortened WAI without the list of diseases were as good as the complete WAI. The WAS showed poorer discrimination in manual and non-manual workers. The WAI without the list of diseases is a good alternative to the complete WAI to identify non-sicklisted workers at risk of future LTSA durations ≥2, ≥4 and ≥6 weeks. © The Author 2015. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Telomere shortening impairs regeneration of the olfactory epithelium in response to injury but not under homeostatic conditions.

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Masami Watabe-Rudolph

Full Text Available Atrophy of the olfactory epithelium (OE associated with impaired olfaction and dry nose represents one of the most common phenotypes of human aging. Impairment in regeneration of a functional olfactory epithelium can also occur in response to injury due to infection or nasal surgery. These complications occur more frequently in aged patients. Although age is the most unifying risk factor for atrophic changes and functional decline of the olfactory epithelium, little is known about molecular mechanisms that could influence maintenance and repair of the olfactory epithelium. Here, we analyzed the influence of telomere shortening (a basic mechanism of cellular aging on homeostasis and regenerative reserve in response to chemical induced injury of the OE in late generation telomere knockout mice (G3 mTerc(-/- with short telomeres compared to wild type mice (mTerc(+/+ with long telomeres. The study revealed no significant influence of telomere shortening on homeostatic maintenance of the OE during mouse aging. In contrast, the regenerative response to chemical induced injury of the OE was significantly impaired in G3 mTerc(-/- mice compared to mTerc(+/+ mice. Seven days after chemical induced damage, G3 mTerc(-/- mice exhibited significantly enlarged areas of persisting atrophy compared to mTerc(+/+ mice (p = 0.031. Telomere dysfunction was associated with impairments in cell proliferation in the regenerating epithelium. Deletion of the cell cycle inhibitor, Cdkn1a (p21 rescued defects in OE regeneration in telomere dysfunctional mice. Together, these data indicate that telomere shortening impairs the regenerative capacity of the OE by impairing cell cycle progression in a p21-dependent manner. These findings could be relevant for the impairment in OE function in elderly people.

Dynamic Contractility and Efficiency Impairments in Stretch-Shortening Cycle Are Stretch-Load-Dependent After Training-Induced Muscle Damage

NARCIS (Netherlands)

Vaczi, Mark; Racz, Levente; Hortobagyi, Tibor; Tihanyi, Jozsef

Vaczi, M, Racz, L, Hortobagyi, T, and Tihanyi, J. Dynamic contractility and efficiency impairments in stretch-shortening cycle are stretch-load-dependent after training-induced muscle damage. J Strength Cond Res 27(8): 2171-2179, 2013To determine the acute task and stretch-load dependency of

Intramedullary stabilization and over-nail lengthening as two-stage treatment of femoral nonunion with shortening. Case study.

Science.gov (United States)

Kącki, Wojciech; Jasiewicz, Barbara; Radło, Paweł

2014-01-01

Nonunion is one of the most serious complications of long bone fractures. It may be accompanied by a shortening of the segment. The authors describe the case of a 21-year-old woman with a post-traumatic nonunion with shortening of the femur. Treatment was divided into two stages: first, a previously placed nail was removed and new intramedullary stabilization was carried out while bone defects were filled with a bone graft substitute and platelet rich plasma was administered. After the nonunion had healed, the femur was lengthened over an external fixator and an intramedullary nail, resulting in equality of limb length. After eight years of follow-up, the lower limbs remain equal with a properly aligned long axis of the lower limb operated on and a full range of motion in the joints. The treatment strategy described in our article may be an alternative to one-stage surgery if the patient does not consent to it or in the presence of contraindications, but it is associated with a longer treatment time and necessity of additional surgeries.

Maximal intended velocity training induces greater gains in bench press performance than deliberately slower half-velocity training.

Science.gov (United States)

González-Badillo, Juan José; Rodríguez-Rosell, David; Sánchez-Medina, Luis; Gorostiaga, Esteban M; Pareja-Blanco, Fernando

2014-01-01

The purpose of this study was to compare the effect on strength gains of two isoinertial resistance training (RT) programmes that only differed in actual concentric velocity: maximal (MaxV) vs. half-maximal (HalfV) velocity. Twenty participants were assigned to a MaxV (n = 9) or HalfV (n = 11) group and trained 3 times per week during 6 weeks using the bench press (BP). Repetition velocity was controlled using a linear velocity transducer. A complementary study (n = 10) aimed to analyse whether the acute metabolic (blood lactate and ammonia) and mechanical response (velocity loss) was different between the MaxV and HalfV protocols used. Both groups improved strength performance from pre- to post-training, but MaxV resulted in significantly greater gains than HalfV in all variables analysed: one-repetition maximum (1RM) strength (18.2 vs. 9.7%), velocity developed against all (20.8 vs. 10.0%), light (11.5 vs. 4.5%) and heavy (36.2 vs. 17.3%) loads common to pre- and post-tests. Light and heavy loads were identified with those moved faster or slower than 0.80 m · s(-1) (∼ 60% 1RM in BP). Lactate tended to be significantly higher for MaxV vs. HalfV, with no differences observed for ammonia which was within resting values. Both groups obtained the greatest improvements at the training velocities (≤ 0.80 m · s(-1)). Movement velocity can be considered a fundamental component of RT intensity, since, for a given %1RM, the velocity at which loads are lifted largely determines the resulting training effect. BP strength gains can be maximised when repetitions are performed at maximal intended velocity.

Accelerated radial Fourier-velocity encoding using compressed sensing

Energy Technology Data Exchange (ETDEWEB)

Hilbert, Fabian; Han, Dietbert [Wuerzburg Univ. (Germany). Inst. of Radiology; Wech, Tobias; Koestler, Herbert [Wuerzburg Univ. (Germany). Inst. of Radiology; Wuerzburg Univ. (Germany). Comprehensive Heart Failure Center (CHFC)

2014-10-01

Purpose:Phase Contrast Magnetic Resonance Imaging (MRI) is a tool for non-invasive determination of flow velocities inside blood vessels. Because Phase Contrast MRI only measures a single mean velocity per voxel, it is only applicable to vessels significantly larger than the voxel size. In contrast, Fourier Velocity Encoding measures the entire velocity distribution inside a voxel, but requires a much longer acquisition time. For accurate diagnosis of stenosis in vessels on the scale of spatial resolution, it is important to know the velocity distribution of a voxel. Our aim was to determine velocity distributions with accelerated Fourier Velocity Encoding in an acquisition time required for a conventional Phase Contrast image. Materials and Methods:We imaged the femoral artery of healthy volunteers with ECG - triggered, radial CINE acquisition. Data acquisition was accelerated by undersampling, while missing data were reconstructed by Compressed Sensing. Velocity spectra of the vessel were evaluated by high resolution Phase Contrast images and compared to spectra from fully sampled and undersampled Fourier Velocity Encoding. By means of undersampling, it was possible to reduce the scan time for Fourier Velocity Encoding to the duration required for a conventional Phase Contrast image. Results:Acquisition time for a fully sampled data set with 12 different Velocity Encodings was 40 min. By applying a 12.6 - fold retrospective undersampling, a data set was generated equal to 3:10 min acquisition time, which is similar to a conventional Phase Contrast measurement. Velocity spectra from fully sampled and undersampled Fourier Velocity Encoded images are in good agreement and show the same maximum velocities as compared to velocity maps from Phase Contrast measurements. Conclusion: Compressed Sensing proved to reliably reconstruct Fourier Velocity Encoded data. Our results indicate that Fourier Velocity Encoding allows an accurate determination of the velocity

Accelerated radial Fourier-velocity encoding using compressed sensing

International Nuclear Information System (INIS)

Hilbert, Fabian; Han, Dietbert

2014-01-01

Purpose:Phase Contrast Magnetic Resonance Imaging (MRI) is a tool for non-invasive determination of flow velocities inside blood vessels. Because Phase Contrast MRI only measures a single mean velocity per voxel, it is only applicable to vessels significantly larger than the voxel size. In contrast, Fourier Velocity Encoding measures the entire velocity distribution inside a voxel, but requires a much longer acquisition time. For accurate diagnosis of stenosis in vessels on the scale of spatial resolution, it is important to know the velocity distribution of a voxel. Our aim was to determine velocity distributions with accelerated Fourier Velocity Encoding in an acquisition time required for a conventional Phase Contrast image. Materials and Methods:We imaged the femoral artery of healthy volunteers with ECG - triggered, radial CINE acquisition. Data acquisition was accelerated by undersampling, while missing data were reconstructed by Compressed Sensing. Velocity spectra of the vessel were evaluated by high resolution Phase Contrast images and compared to spectra from fully sampled and undersampled Fourier Velocity Encoding. By means of undersampling, it was possible to reduce the scan time for Fourier Velocity Encoding to the duration required for a conventional Phase Contrast image. Results:Acquisition time for a fully sampled data set with 12 different Velocity Encodings was 40 min. By applying a 12.6 - fold retrospective undersampling, a data set was generated equal to 3:10 min acquisition time, which is similar to a conventional Phase Contrast measurement. Velocity spectra from fully sampled and undersampled Fourier Velocity Encoded images are in good agreement and show the same maximum velocities as compared to velocity maps from Phase Contrast measurements. Conclusion: Compressed Sensing proved to reliably reconstruct Fourier Velocity Encoded data. Our results indicate that Fourier Velocity Encoding allows an accurate determination of the velocity

Accelerated radial Fourier-velocity encoding using compressed sensing.

Science.gov (United States)

Hilbert, Fabian; Wech, Tobias; Hahn, Dietbert; Köstler, Herbert

2014-09-01

Phase Contrast Magnetic Resonance Imaging (MRI) is a tool for non-invasive determination of flow velocities inside blood vessels. Because Phase Contrast MRI only measures a single mean velocity per voxel, it is only applicable to vessels significantly larger than the voxel size. In contrast, Fourier Velocity Encoding measures the entire velocity distribution inside a voxel, but requires a much longer acquisition time. For accurate diagnosis of stenosis in vessels on the scale of spatial resolution, it is important to know the velocity distribution of a voxel. Our aim was to determine velocity distributions with accelerated Fourier Velocity Encoding in an acquisition time required for a conventional Phase Contrast image. We imaged the femoral artery of healthy volunteers with ECG-triggered, radial CINE acquisition. Data acquisition was accelerated by undersampling, while missing data were reconstructed by Compressed Sensing. Velocity spectra of the vessel were evaluated by high resolution Phase Contrast images and compared to spectra from fully sampled and undersampled Fourier Velocity Encoding. By means of undersampling, it was possible to reduce the scan time for Fourier Velocity Encoding to the duration required for a conventional Phase Contrast image. Acquisition time for a fully sampled data set with 12 different Velocity Encodings was 40 min. By applying a 12.6-fold retrospective undersampling, a data set was generated equal to 3:10 min acquisition time, which is similar to a conventional Phase Contrast measurement. Velocity spectra from fully sampled and undersampled Fourier Velocity Encoded images are in good agreement and show the same maximum velocities as compared to velocity maps from Phase Contrast measurements. Compressed Sensing proved to reliably reconstruct Fourier Velocity Encoded data. Our results indicate that Fourier Velocity Encoding allows an accurate determination of the velocity distribution in vessels in the order of the voxel size. Thus

Shortening a Patient Experiences Survey for Medical Homes

Directory of Open Access Journals (Sweden)

Judy H. Ng

2015-12-01

Full Text Available The Consumer Assessment of Healthcare Providers and Systems—Patient-Centered Medical Home (CAHPS PCMH Survey assesses patient experiences reflecting domains of care related to general patient experience (access to care, communication with providers, office staff interaction, provider rating and PCMH-specific aspects of patient care (comprehensiveness of care, self-management support, shared decision making. The current work compares psychometric properties of the current survey and a proposed shortened version of the survey (from 52 to 26 adult survey items, from 66 to 31 child survey items. The revisions were based on initial psychometric analysis and stakeholder input regarding survey length concerns. A total of 268 practices voluntarily submitted adult surveys and 58 submitted child survey data to the National Committee for Quality Assurance in 2013. Mean unadjusted scores, practice-level item and composite reliability, and item-to-scale correlations were calculated. Results show that the shorter adult survey has lower reliability, but still it still meets general definitions of a sound survey for the adult version, and resulted in few changes to mean scores. The impact was more problematic for the pediatric version. Further testing is needed to investigate approaches to improving survey response and the relevance of survey items in informing quality improvement.

Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin

Directory of Open Access Journals (Sweden)

Seok-Hyung Kim

2011-03-01

Tuberous sclerosis complex (TSC is an autosomal dominant disease caused by mutations in either the TSC1 (encodes hamartin or TSC2 (encodes tuberin genes. Patients with TSC have hamartomas in various organs throughout the whole body, most notably in the brain, skin, eye, heart, kidney and lung. To study the development of hamartomas, we generated a zebrafish model of TSC featuring a nonsense mutation (vu242 in the tsc2 gene. This tsc2vu242 allele encodes a truncated Tuberin protein lacking the GAP domain, which is required for inhibition of Rheb and of the TOR kinase within TORC1. We show that tsc2vu242 is a recessive larval-lethal mutation that causes increased cell size in the brain and liver. Greatly elevated TORC1 signaling is observed in tsc2vu242/vu242 homozygous zebrafish, and is moderately increased in tsc2vu242/+ heterozygotes. Forebrain neurons are poorly organized in tsc2vu242/vu242 homozygous mutants, which have extensive gray and white matter disorganization and ectopically positioned cells. Genetic mosaic analyses demonstrate that tsc2 limits TORC1 signaling in a cell-autonomous manner. However, in chimeric animals, tsc2vu242/vu242 mutant cells also mislocalize wild-type host cells in the forebrain in a non-cell-autonomous manner. These results demonstrate a highly conserved role of tsc2 in zebrafish and establish a new animal model for studies of TSC. The finding of a non-cell-autonomous function of mutant cells might help explain the formation of brain hamartomas and cortical malformations in human TSC.

Questions Students Ask: About Terminal Velocity.

Science.gov (United States)

Meyer, Earl R.; Nelson, Jim

1984-01-01

If a ball were given an initial velocity in excess of its terminal velocity, would the upward force of air resistance (a function of velocity) be greater than the downward force of gravity and thus push the ball back upwards? An answer to this question is provided. (JN)

The radial velocity, velocity dispersion, and mass-to-light ratio of the Sculptor dwarf galaxy

Science.gov (United States)

Armandroff, T. E.; Da Costa, G. S.

1986-01-01

The radial velocity, velocity dispersion, and mass-to-light ratio for 16 K giants in the Sculptor dwarf galaxy are calculated. Spectra at the Ca II triplet are analyzed using cross-correlation techniques in order to obtain the mean velocity of + 107.4 + or - 2.0 km/s. The dimensional velocity dispersion estimated as 6.3 (+1.1, -1.3) km/s is combined with the calculated core radius and observed central surface brightness to produce a mass-to-light ratio of 6.0 in solar units. It is noted that the data indicate that the Sculptor contains a large amount of mass not found in globular clusters, and the mass is either in the form of remnant stars or low-mass dwarfs.

Magellanic penguin telomeres do not shorten with age with increased reproductive effort, investment, and basal corticosterone.

Science.gov (United States)

Cerchiara, Jack A; Risques, Rosa Ana; Prunkard, Donna; Smith, Jeffrey R; Kane, Olivia J; Boersma, P Dee

2017-08-01

All species should invest in systems that enhance longevity; however, a fundamental adult life-history trade-off exists between the metabolic resources allocated to maintenance and those allocated to reproduction. Long-lived species will invest more in reproduction than in somatic maintenance as they age. We investigated this trade-off by analyzing correlations among telomere length, reproductive effort and output, and basal corticosterone in Magellanic penguins ( Spheniscus magellanicus ). Telomeres shorten with age in most species studied to date, and may affect adult survival. High basal corticosterone is indicative of stressful conditions. Corticosterone, and stress, has been linked to telomere shortening in other species. Magellanic penguins are a particularly good model organism for this question as they are an unusually long-lived species, exceeding their mass-adjusted predicted lifespan by 26%. Contrary to our hypothesis, we found adults aged 5 years to over 24 years of age had similar telomere lengths. Telomeres of adults did not shorten over a 3-year period, regardless of the age of the individual. Neither telomere length, nor the rate at which the telomeres changed over these 3 years, correlated with breeding frequency or investment. Older females also produced larger volume clutches until approximately 15 years old and larger eggs produced heavier fledglings. Furthermore, reproductive success ( chicks fledged/eggs laid ) is maintained as females aged. Basal corticosterone, however, was not correlated with telomere length in adults and suggests that low basal corticosterone may play a role in the telomere maintenance we observed. Basal corticosterone also declined during the breeding season and was positively correlated with the age of adult penguins. This higher basal corticosterone in older individuals, and consistent reproductive success, supports the prediction that Magellanic penguins invest more in reproduction as they age. Our results

The development of the EORTC QLQ-C15-PAL: a shortened questionnaire for cancer patients in palliative care

NARCIS (Netherlands)

Groenvold, Mogens; Petersen, Morten Aa; Aaronson, Neil K.; Arraras, Juan I.; Blazeby, Jane M.; Bottomley, Andrew; Fayers, Peter M.; de Graeff, Alexander; Hammerlid, Eva; Kaasa, Stein; Sprangers, Mirjam A. G.; Bjorner, Jakob B.

2006-01-01

This study aimed at developing a shortened version of the EORTC QLQ-C30, one of the most widely used health-related quality of life questionnaires in oncology, for palliative care research. The study included interviews with 41 patients and 66 health care professionals in palliative care to

Application of Vectors to Relative Velocity

Science.gov (United States)

Tin-Lam, Toh

2004-01-01

The topic 'relative velocity' has recently been introduced into the Cambridge Ordinary Level Additional Mathematics syllabus under the application of Vectors. In this note, the results of relative velocity and the 'reduction to rest' technique of teaching relative velocity are derived mathematically from vector algebra, in the hope of providing…

Computing discharge using the index velocity method

Science.gov (United States)

Levesque, Victor A.; Oberg, Kevin A.

2012-01-01

Application of the index velocity method for computing continuous records of discharge has become increasingly common, especially since the introduction of low-cost acoustic Doppler velocity meters (ADVMs) in 1997. Presently (2011), the index velocity method is being used to compute discharge records for approximately 470 gaging stations operated and maintained by the U.S. Geological Survey. The purpose of this report is to document and describe techniques for computing discharge records using the index velocity method. Computing discharge using the index velocity method differs from the traditional stage-discharge method by separating velocity and area into two ratings—the index velocity rating and the stage-area rating. The outputs from each of these ratings, mean channel velocity (V) and cross-sectional area (A), are then multiplied together to compute a discharge. For the index velocity method, V is a function of such parameters as streamwise velocity, stage, cross-stream velocity, and velocity head, and A is a function of stage and cross-section shape. The index velocity method can be used at locations where stage-discharge methods are used, but it is especially appropriate when more than one specific discharge can be measured for a specific stage. After the ADVM is selected, installed, and configured, the stage-area rating and the index velocity rating must be developed. A standard cross section is identified and surveyed in order to develop the stage-area rating. The standard cross section should be surveyed every year for the first 3 years of operation and thereafter at a lesser frequency, depending on the susceptibility of the cross section to change. Periodic measurements of discharge are used to calibrate and validate the index rating for the range of conditions experienced at the gaging station. Data from discharge measurements, ADVMs, and stage sensors are compiled for index-rating analysis. Index ratings are developed by means of regression

Shortening of an existing generic online health-related quality of life instrument for dogs.

Science.gov (United States)

Reid, J; Wiseman-Orr, L; Scott, M

2017-10-11

Development, initial validation and reliability testing of a shortened version of a web-based questionnaire instrument to measure generic health-related quality of life in companion dogs, to facilitate smartphone and online use. The original 46 items were reduced using expert judgment and factor analysis. Items were removed on the basis of item loadings and communalities on factors identified through factor analysis of responses from owners of healthy and unwell dogs, intrafactor item correlations, readability of items in the UK, USA and Australia and ability of individual items to discriminate between healthy and unwell dogs. Validity was assessed through factor analysis and a field trial using a "known groups" approach. Test-retest reliability was assessed using intraclass correlation coefficients. The new instrument comprises 22 items, each of which was rated by dog owners using a 7-point Likert scale. Factor analysis revealed a structure with four health-related quality of life domains (energetic/enthusiastic, happy/content, active/comfortable, and calm/relaxed) accounting for 72% of the variability in the data compared with 64% for the original instrument. The field test involving 153 healthy and unwell dogs demonstrated good discriminative properties and high intraclass correlation coefficients. The 22-item shortened form is superior to the original instrument and can be accessed via a mobile phone app. This is likely to increase the acceptability to dog owners as a routine wellness measure in health care packages and as a therapeutic monitoring tool. © 2017 British Small Animal Veterinary Association.

Adding Stiffness to the Foot Modulates Soleus Force-Velocity Behaviour during Human Walking

Science.gov (United States)

Takahashi, Kota Z.; Gross, Michael T.; van Werkhoven, Herman; Piazza, Stephen J.; Sawicki, Gregory S.

2016-07-01

Previous studies of human locomotion indicate that foot and ankle structures can interact in complex ways. The structure of the foot defines the input and output lever arms that influences the force-generating capacity of the ankle plantar flexors during push-off. At the same time, deformation of the foot may dissipate some of the mechanical energy generated by the plantar flexors during push-off. We investigated this foot-ankle interplay during walking by adding stiffness to the foot through shoes and insoles, and characterized the resulting changes in in vivo soleus muscle-tendon mechanics using ultrasonography. Added stiffness decreased energy dissipation at the foot (p < 0.001) and increased the gear ratio (i.e., ratio of ground reaction force and plantar flexor muscle lever arms) (p < 0.001). Added foot stiffness also altered soleus muscle behaviour, leading to greater peak force (p < 0.001) and reduced fascicle shortening speed (p < 0.001). Despite this shift in force-velocity behaviour, the whole-body metabolic cost during walking increased with added foot stiffness (p < 0.001). This increased metabolic cost is likely due to the added force demand on the plantar flexors, as walking on a more rigid foot/shoe surface compromises the plantar flexors’ mechanical advantage.

Demonstration of a Vector Velocity Technique

DEFF Research Database (Denmark)

Hansen, Peter Møller; Pedersen, Mads M.; Hansen, Kristoffer L.

2011-01-01

With conventional Doppler ultrasound it is not possible to estimate direction and velocity of blood flow, when the angle of insonation exceeds 60–70°. Transverse oscillation is an angle independent vector velocity technique which is now implemented on a conventional ultrasound scanner. In this pa......With conventional Doppler ultrasound it is not possible to estimate direction and velocity of blood flow, when the angle of insonation exceeds 60–70°. Transverse oscillation is an angle independent vector velocity technique which is now implemented on a conventional ultrasound scanner...

Vector blood velocity estimation in medical ultrasound

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt; Gran, Fredrik; Udesen, Jesper

2006-01-01

Two methods for making vector velocity estimation in medical ultrasound are presented. All of the techniques can find both the axial and transverse velocity in the image and can be used for displaying both the correct velocity magnitude and direction. The first method uses a transverse oscillation...... in the ultrasound field to find the transverse velocity. In-vivo examples from the carotid artery are shown, where complex turbulent flow is found in certain parts of the cardiac cycle. The second approach uses directional beam forming along the flow direction to estimate the velocity magnitude. Using a correlation...... search can also yield the direction, and the full velocity vector is thereby found. An examples from a flow rig is shown....

Femoral neck shortening in adult patients under the age of 55 years is associated with worse functional outcomes: Analysis of the prospective multi-center study of hip fracture outcomes in China (SHOC).

Science.gov (United States)

Slobogean, Gerard P; Stockton, David J; Zeng, Bing-Fang; Wang, Dong; Ma, Baotong; Pollak, Andrew N

2017-08-01

Young femoral neck fracture patients require surgical fixation to preserve the native hip joint and accommodate increased functional demands. Recent reports have identified a high incidence of fracture shortening and this may have negative functional consequences. We sought to determine if fracture shortening is associated with poor functional outcome in young femoral neck fracture patients. One hundred and forty-two patients with femoral neck fractures age 18-55 were recruited in this prospective cohort study across three Level 1 trauma hospitals in Mainland China. Patient-reported and objective functional outcomes were measured with the Harris Hip Score (HHS), Timed Up and Go (TUG), and SF-36 Physical Component Summary (SF-36 PCS) at 12 months. Radiographic fracture shortening was measured along the long axis of the femoral neck and corrected for magnification. Severe shortening was defined as ≥10mm. The primary analysis measured associations between severe radiographic shortening and HHS at one-year post-fixation. One hundred and two patients had complete radiographic and functional outcomes available for analysis at one year. The mean age of participants was 43.7±10.8years and 53% were male. Fifty-five percent of fractures were displaced and 37% were vertically orientated (Pauwels Type 3). The mean functional outcome scores were: HHS 90.0±10.8, TUG 12.0±5.1s, and PCS 48.5±8.6. Severe shortening occurred in 13% of patients and was associated with worse functional outcome scores: HHS mean difference 9.9 (p=0.025), TUG mean difference 3.2s (p=0.082), and PCS mean difference 5.4 (p=0.055). Severe shortening is associated with clinically important decreases in functional outcome as measured by HHS following fixation of young femoral neck fractures, occurring in 13% of patients in this population. The principle of fracture site compression utilized by modern constructs may promote healing; however, excessive shortening is associated with worse patient

High-velocity frictional properties of gabbro

Science.gov (United States)

Tsutsumi, Akito; Shimamoto, Toshihiko

High-velocity friction experiments have been performed on a pair of hollow-cylindrical specimens of gabbro initially at room temperature, at slip rates from 7.5 mm/s to 1.8 m/s, with total circumferential displacements of 125 to 174 m, and at normal stresses to 5 MPa, using a rotary-shear high-speed friction testing machine. Steady-state friction increases slightly with increasing slip rate at slip rates to about 100 mm/s (velocity strengthening) and it decreases markedly with increasing slip rate at higher velocities (velocity weakening). Steady-state friction in the velocity weakening regime is lower for the non-melting case than the frictional melting case, due perhaps to severe thermal fracturing. A very large peak friction is always recognized upon the initiation of visible frictional melting, presumably owing to the welding of fault surfaces upon the solidification of melt patches. Frictional properties thus change dramatically with increasing displacement at high velocities, and such a non-linear effect must be incorporated into the analysis of earthquake initiation processes.

Velocity distribution in snow avalanches

Science.gov (United States)

Nishimura, K.; Ito, Y.

1997-12-01

In order to investigate the detailed structure of snow avalanches, we have made snow flow experiments at the Miyanomori ski jump in Sapporo and systematic observations in the Shiai-dani, Kurobe Canyon. In the winter of 1995-1996, a new device to measure static pressures was used to estimate velocities in the snow cloud that develops above the flowing layer of avalanches. Measurements during a large avalanche in the Shiai-dani which damaged and destroyed some instruments indicate velocities increased rapidly to more than 50 m/s soon after the front. Velocities decreased gradually in the following 10 s. Velocities of the lower flowing layer were also calculated by differencing measurement of impact pressure. Both recordings in the snow cloud and in the flowing layer changed with a similar trend and suggest a close interaction between the two layers. In addition, the velocity showed a periodic change. Power spectrum analysis of the impact pressure and the static pressure depression showed a strong peak at a frequency between 4 and 6 Hz, which might imply the existence of either ordered structure or a series of surges in the flow.

Sound Velocity in Soap Foams

International Nuclear Information System (INIS)

Wu Gong-Tao; Lü Yong-Jun; Liu Peng-Fei; Li Yi-Ning; Shi Qing-Fan

2012-01-01

The velocity of sound in soap foams at high gas volume fractions is experimentally studied by using the time difference method. It is found that the sound velocities increase with increasing bubble diameter, and asymptotically approach to the value in air when the diameter is larger than 12.5 mm. We propose a simple theoretical model for the sound propagation in a disordered foam. In this model, the attenuation of a sound wave due to the scattering of the bubble wall is equivalently described as the effect of an additional length. This simplicity reasonably reproduces the sound velocity in foams and the predicted results are in good agreement with the experiments. Further measurements indicate that the increase of frequency markedly slows down the sound velocity, whereas the latter does not display a strong dependence on the solution concentration

Diagnostic accuracy of the original 30-item and shortened versions of the Geriatric Depression Scale in nursing home patients

NARCIS (Netherlands)

Jongenelis, K; Eisses, AMH; Gerritsen, DL; Beekman, ATF; Kluiter, H; Ribbe, MW

2005-01-01

Objective To determine the diagnostic accuracy of the 30-item and shortened versions of the Geriatric Depression Scale (GDS) in diagnosing depression in older nursing home patients. Method Three hundred and thirty-three older nursing home patients participated in a prospective cross-sectional study

Diagnostic accuracy of the original 30-item and shortened versions of the Geriatric Depression Scale in nursing home patients

NARCIS (Netherlands)

Jongenelis, K; Eisses, AMH; Gerritsen, DL; Beekman, ATF; Kluiter, H; Ribbe, MW

Objective To determine the diagnostic accuracy of the 30-item and shortened versions of the Geriatric Depression Scale (GDS) in diagnosing depression in older nursing home patients. Method Three hundred and thirty-three older nursing home patients participated in a prospective cross-sectional study

Semi-automated detection of fractional shortening in zebrafish embryo heart videos

Directory of Open Access Journals (Sweden)

Nasrat Sara

2016-09-01

Full Text Available Quantifying cardiac functions in model organisms like embryonic zebrafish is of high importance in small molecule screens for new therapeutic compounds. One relevant cardiac parameter is the fractional shortening (FS. A method for semi-automatic quantification of FS in video recordings of zebrafish embryo hearts is presented. The software provides automated visual information about the end-systolic and end-diastolic stages of the heart by displaying corresponding colored lines into a Motion-mode display. After manually marking the ventricle diameters in frames of end-systolic and end-diastolic stages, the FS is calculated. The software was evaluated by comparing the results of the determination of FS with results obtained from another established method. Correlations of 0.96 < r < 0.99 between the two methods were found indicating that the new software provides comparable results for the determination of the FS.

Use of TCSR with Split Windings for Shortening the Spar Cycle Time in 500 kV Lines

Energy Technology Data Exchange (ETDEWEB)

Matinyan, A. M., E-mail: al-drm@mail.ru; Peshkov, M. V.; Karpov, V. N.; Alekseev, N. A. [JSC “R& D Center at Federal Grid Company of Unified Power System,” (Russian Federation)

2017-01-15

The arc-fault recharge phenomenon in single-phase automatic reclosure (SPAR) of a line is examined. Abrief description is given of the design of a 500 kV thyristor controlled shunt reactor (TCSR) with split valve-side windings. This type of TCSR is shown to effectively quench a single-phase arc fault in a power transmission line and shortens the SPAR cycle time.

MÉTODO SIMPLES PARA ESTIMAR ENCURTAMENTO PELO FRIO EM CARNE BOVINA A SIMPLE METHOD TO ESTIMATE COLD SHORTENING IN BEEF

Directory of Open Access Journals (Sweden)

Riana Jordão Barrozo Heinemann

2002-04-01

Full Text Available É bem conhecido o fato de que o encurtamento pelo frio pode influenciar negativamente a textura da carne. Por isso, a determinação do grau de contração do tecido muscular é um recurso analítico de grande importância quando se estuda a otimização dos procedimentos industriais. Neste trabalho, foram avaliadas comparativamente duas metodologias de microscopia. Para isso, os músculos Biceps femoris, Longissimus dorsi e Semimembranosus obtidos de nove carcaças bovinas com três diferentes graus de acabamento foram analisados de forma pareada por ambos os métodos. O músculo Longissimus dorsi apresentou menor comprimento de sarcômero e o m. Semimembranosus o maior (p0,05, revelando a possibilidade de emprego do método mais simples.The negative influence of cold shortening on meat texture is well known. Because of that, the determination of the muscle contraction extent represents an important analytical tool for the optimization of the industrial procedures. In this work, two methodologies to evaluate cold shortening were compared. Biceps femoris, Longissimus dorsi and Semimembranosus muscles from 9 cattle carcasses with three different fat thickness grades were paired analyzed by both methodologies. Longissimus dorsi muscle showed the shortest sarcomere length while Semimembranosus m. showed the longest one (p0.05, which suggests the possibility of using the simpler method for cold shortening evaluation.

Long-term follow-up indicates unimpaired oral health-related quality of life for people having shortened dental arches

NARCIS (Netherlands)

Gerritsen, A.E.; Witter, D.J.; Creugers, N.H.J.

2017-01-01

OBJECTIVES: To assess and analyse OHRQoL of people with shortened dental arches (SDA) in a long-term cohort study. METHODS: All participants of a long-term cohort study on SDA who were still attending the university dental clinic and still had an SDA (SDA group) with 3-5 posterior occluding pairs

A design for a V and V and UQ discovery process

International Nuclear Information System (INIS)

Knupp, Patrick Michael; Urbina, Angel

2011-01-01

There is currently sparse literature on how to implement systematic and comprehensive processes for modern V and V/UQ (VU) within large computational simulation projects. Important design requirements have been identified in order to construct a viable 'system' of processes. Significant processes that are needed include discovery, accumulation, and assessment. A preliminary design is presented for a VU Discovery process that accounts for an important subset of the requirements. The design uses a hierarchical approach to set context and a series of place-holders that identify the evidence and artifacts that need to be created in order to tell the VU story and to perform assessments. The hierarchy incorporates VU elements from a Predictive Capability Maturity Model and uses questionnaires to define critical issues in VU. The place-holders organize VU data within a central repository that serves as the official VU record of the project. A review process ensures that those who will contribute to the record have agreed to provide the evidence identified by the Discovery process. VU expertise is an essential part of this process and ensures that the roadmap provided by the Discovery process is adequate. Both the requirements and the design were developed to support the Nuclear Energy Advanced Modeling and Simulation Waste project, which is developing a set of advanced codes for simulating the performance of nuclear waste storage sites. The Waste project served as an example to keep the design of the VU Discovery process grounded in practicalities. However, the system is represented abstractly so that it can be applied to other M and S projects.

Distinguishing zero-group-velocity modes in photonic crystals

International Nuclear Information System (INIS)

Ghebrebrhan, M.; Ibanescu, M.; Johnson, Steven G.; Soljacic, M.; Joannopoulos, J. D.

2007-01-01

We examine differences between various zero-group-velocity modes in photonic crystals, including those that arise from Bragg diffraction, anticrossings, and band repulsion. Zero-group velocity occurs at points where the group velocity changes sign, and therefore is conceptually related to 'left-handed' media, in which the group velocity is opposite to the phase velocity. We consider this relationship more quantitatively in terms of the Fourier decomposition of the modes, by defining a measure of how much the ''average'' phase velocity is parallel to the group velocity--an anomalous region is one in which they are mostly antiparallel. We find that this quantity can be used to qualitatively distinguish different zero-group-velocity points. In one dimension, such anomalous regions are found never to occur. In higher dimensions, they are exhibited around certain zero-group-velocity points, and lead to unusual enhanced confinement behavior in microcavities

Settling velocities in batch sedimentation

International Nuclear Information System (INIS)

Fricke, A.M.; Thompson, B.E.

1982-10-01

The sedimentation of mixtures containing one and two sizes of spherical particles (44 and 62 μm in diameter) was studied. Radioactive tracing with 57 Co was used to measure the settling velocities. The ratio of the settling velocity U of uniformly sized particles to the velocity predicted to Stokes' law U 0 was correlated to an expression of the form U/U 0 = epsilon/sup α/, where epsilon is the liquid volume fraction and α is an empirical constant, determined experimentally to be 4.85. No effect of viscosity on the ratio U/U 0 was observed as the viscosity of the liquid medium was varied from 1x10 -3 to 5x10 -3 Pa.s. The settling velocities of particles in a bimodal mixture were fit by the same correlation; the ratio U/U 0 was independent of the concentrations of different-sized particles

Imunidade antitruste às Ações Governamentais no contexto da desregulação do setor de telecomunicações: uma análise a partir do julgamento do caso VU-M pelo CADE

Directory of Open Access Journals (Sweden)

Deborah Batista Caixeta

2014-05-01

Full Text Available Propósito – O objetivo deste ensaio é examinar a postura adotada pelo CADE com relação às medidas regulatórias adotadas pela ANATEL na fixação do valor de interconexão de rede (VU-M, sob a perspectiva da State Action Doctrine no contexto da desregulação do setor de telecomunicações. Metodologia/abordagem/design – O texto propõe uma abordagem relativa às teorias de desregulação do setor de telecomunicações e o impacto que as decisões da autoridade antitruste de isenção concorrencial possuem neste movimento, a partir da análise do caso VU-M recentemente julgado pelo CADE. Resultados – A concessão de isenções antitruste pelo CADE ainda parece seguir a tradicional aplicação da State Action Doctrine centrada na teoria regulatória do interesse público e, consequentemente, a extrema confiança na atuação da agência acaba dificultando o processo de desregulação, principalmente no setor de telecomunicações, notadamente marcado pela antiga estrutura regulatória oligopolista. Implicações práticas – Busca-se, por meio desta análise crítica, oferecer uma abordagem introdutória que possa ser aplicada posteriormente para rediscutir os limites de aplicação da lei de defesa da concorrência a situações acobertadas por medidas regulatórias setoriais. Originalidade/relevância do texto – O ensaio identifica os elementos que se aplicam na dinâmica de interação entre regulação concorrencial e a regulação setorial, a ponto de permitir que a tradicional estrutura de aplicação das normas de concorrência a estes setores possa ser redesenhada para incorporar os objetivos perseguidos pelo movimento de desregulação, no caso, do setor de telecomunicações.

Superhilac real-time velocity measurements

International Nuclear Information System (INIS)

Feinberg, B.; Meaney, D.; Thatcher, R.; Timossi, C.

1987-03-01

Phase probes have been placed in several external beam lines at the LBL heavy ion linear accelerator (SuperHILAC) to provide non-destructive velocity measurements independent of the ion being accelerated. The existing system has been improved to provide the following features: a display refresh rate better than twice per second, a sensitive pseudo-correlation technique to pick out the signal from the noise, simultaneous measurements of up to four ion velocities when more than one beam is being accelerated, and a touch-screen operator interface. These improvements allow the system to be used as a routine tuning aid and beam velocity monitor

Fractals control in particle's velocity

International Nuclear Information System (INIS)

Zhang Yongping; Liu Shutang; Shen Shulan

2009-01-01

Julia set, a fractal set of the literature of nonlinear physics, has significance for the engineering applications. For example, the fractal structure characteristics of the generalized M-J set could visually reflect the change rule of particle's velocity. According to the real world requirement, the system need show various particle's velocity in some cases. Thus, the control of the nonlinear behavior, i.e., Julia set, has attracted broad attention. In this work, an auxiliary feedback control is introduced to effectively control the Julia set that visually reflects the change rule of particle's velocity. It satisfies the performance requirement of the real world problems.

Effects of Estrogen Fluctuation during the Menstrual Cycle on the Response to Stretch-Shortening Exercise in Females

Directory of Open Access Journals (Sweden)

Saulė Sipavičienė

2013-01-01

Full Text Available The aim of this study was to investigate whether variation in estrogen levels during the menstrual cycle influences susceptibility to exercise-induced muscle damage after stretch-shortening cycle exercise. Physically active women (n=18; age = 20.2 ± 1.7 yr participated in this research. The subjects performed one session of 100 maximal drop jumps on day 1 or 2 of the follicular phase and another identical session on day 1 or 2 of the ovulatory phase; the order of the sessions was randomized. Quadriceps femoris muscle peak torque evoked by electrical stimulation and maximal voluntary contraction, muscle pain, and CK activity were measured before and at various times up to 72 h after exercise. It was found that the high estrogen level during the ovulatory phase might be related to an earlier return to baseline muscle strength after strenuous stretch-shortening cycle exercise in that phase compared with the follicular phase. The estrogen effect appears to be highly specific to the damaged site because the differences in most EIMD markers (CK, soreness, and low-frequency fatigue between the two menstrual cycle phases were small.

Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty.

Science.gov (United States)

Tanner, J M; Whitehouse, R H

1976-01-01

New charts for height, weight, height velocity, and weight velocity are presented for clinical (as opposed to population survey) use. They are based on longitudinal-type growth curves, using the same data as in the British 1965 growth standards. In the velocity standards centiles are given for children who are early- and late-maturing as well as for those who mature at the average age (thus extending the use of the previous charts). Limits of normality for the age of occurrence of the adolescent growth spurt are given and also for the successive stages of penis, testes, and pubic hair development in boys, and for stages of breast and pubic hair development in girls. PMID:952550

Low-velocity superconducting accelerating structures

International Nuclear Information System (INIS)

Delayen, J.R.

1990-01-01

The present paper reviews the status of RF superconductivity as applied to low-velocity accelerating properties. Heavy-ion accelerators must accelerate efficiently particles which travel at a velocity much smaller than that of light particles, whose velocity changes along accelerator, and also different particles which have different velocity profiles. Heavy-ion superconducting accelerators operate at frequencies which are lower than high-energy superconducting accelerators. The present paper first discusses the basic features of heavy-ion superconducting structures and linacs. Design choices are then addressed focusing on structure geometry, materials, frequency, phase control, and focusing. The report also gives an outline of the status of superconducting booster projects currently under way at the Argonne National Laboratory, SUNY Stony Brook, Weizmann Institute, University of Washington, Florida State, Saclay, Kansas State, Daresbury, Japanese Atomic Energy Research Institute, Legnaro, Bombay, Sao Paulo, ANU (Canberra), and Munich. Recent developments and future prospects are also described. (N.K.) 68 refs

Velocity Estimate Following Air Data System Failure

National Research Council Canada - National Science Library

McLaren, Scott A

2008-01-01

.... A velocity estimator (VEST) algorithm was developed to combine the inertial and wind velocities to provide an estimate of the aircraft's current true velocity to be used for command path gain scheduling and for display in the cockpit...

Spatially-resolved velocities of thermally-produced spray droplets using a velocity-divided Abel inversion of photographed streaks

Science.gov (United States)

Kawaguchi, Y.; Kobayashi, N.; Yamagata, Y.; Miyazaki, F.; Yamasaki, M.; Muraoka, K.

2017-10-01

Droplet velocities of thermal spray are known to have profound effects on important coating qualities, such as adhesive strength, porosity, and hardness, for various applications. For obtaining the droplet velocities, therefore, the TOF (time-of-flight) technique has been widely used, which relies on observations of emitted radiation from the droplets, where all droplets along the line-of-sight contribute to signals. Because droplets at and near the flow axis mostly contribute coating layers, it has been hoped to get spatially resolved velocities. For this purpose, a velocity-divided Abel inversion was devised from CMOS photographic data. From this result, it has turned out that the central velocity is about 25% higher than that obtained from the TOF technique for the case studied (at the position 150 mm downstream of the plasma spray gun, where substrates for spray coatings are usually placed). Further implications of the obtained results are discussed.

Algorithms for estimating blood velocities using ultrasound

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt

2000-01-01

Ultrasound has been used intensively for the last 15 years for studying the hemodynamics of the human body. Systems for determining both the velocity distribution at one point of interest (spectral systems) and for displaying a map of velocity in real time have been constructed. A number of schemes...... have been developed for performing the estimation, and the various approaches are described. The current systems only display the velocity along the ultrasound beam direction and a velocity transverse to the beam is not detected. This is a major problem in these systems, since most blood vessels...... are parallel to the skin surface. Angling the transducer will often disturb the flow, and new techniques for finding transverse velocities are needed. The various approaches for determining transverse velocities will be explained. This includes techniques using two-dimensional correlation (speckle tracking...

Bulk velocity extraction for nano-scale Newtonian flows

Energy Technology Data Exchange (ETDEWEB)

Zhang, Wenfei, E-mail: zwenfei@gmail.com [Key Laboratory of Mechanical Reliability for Heavy Equipments and Large Structures of Hebei Province, Yanshan University, Qinhuangdao 066004 (China); Sun, Hongyu [Key Laboratory of Mechanical Reliability for Heavy Equipments and Large Structures of Hebei Province, Yanshan University, Qinhuangdao 066004 (China)

2012-04-16

The conventional velocity extraction algorithm in MDS method has difficulty to determine the small flow velocity. This study proposes a new method to calculate the bulk velocity in nano-flows. Based on the Newton's law of viscosity, according to the calculated viscosities and shear stresses, the flow velocity can be obtained by numerical integration. This new method can overcome the difficulty existed in the conventional MDS method and improve the stability of the computational process. Numerical results show that this method is effective for the extraction of bulk velocity, no matter the bulk velocity is large or small. -- Highlights: ► Proposed a new method to calculate the bulk velocity in nano-flows. ► It is effective for the extraction of small bulk velocity. ► The accuracy, convergence and stability of the new method is good.

Bulk velocity extraction for nano-scale Newtonian flows

International Nuclear Information System (INIS)

Zhang, Wenfei; Sun, Hongyu

2012-01-01

The conventional velocity extraction algorithm in MDS method has difficulty to determine the small flow velocity. This study proposes a new method to calculate the bulk velocity in nano-flows. Based on the Newton's law of viscosity, according to the calculated viscosities and shear stresses, the flow velocity can be obtained by numerical integration. This new method can overcome the difficulty existed in the conventional MDS method and improve the stability of the computational process. Numerical results show that this method is effective for the extraction of bulk velocity, no matter the bulk velocity is large or small. -- Highlights: ► Proposed a new method to calculate the bulk velocity in nano-flows. ► It is effective for the extraction of small bulk velocity. ► The accuracy, convergence and stability of the new method is good.

Shallow Geological Structures Triggered During the Mw6.4 Meinong Earthquake and Their Significance in Accommodating Long-term Shortening Across the Foothills of Southwestern Taiwan

Science.gov (United States)

Le Beon, M.; Suppe, J.; Huang, M. H.; Huang, S. T.; Ulum, H. H. M.; Ching, K. E.; Hsieh, Y. H.

2017-12-01

The 2016 Mw6.4 Meinong earthquake generated up to 10 cm surface displacement located 10-35 km W of the epicenter and monitored by InSAR and GPS. In addition to coseismic deformation related to the deep earthquake source, InSAR revealed three sharp surface displacement gradients that suggest slip triggering on shallow structures. To characterize these shallow structures, we build two EW regional balanced cross-sections, based on surface geology, subsurface data, and coseismic and interseismic geodetic data. From the Coastal Plain to the eastern edge of the coseismic deformation area, we propose a series of three active W-dipping back-thrusts: the Houchiali fault, the Napalin-Pitou back-thrust, and the Lungchuan back-thrust. They all root on the 3.5-4.0 km deep Tainan detachment located near the base of the 3-km-thick Plio-Pleistocene Gutingkeng mudstone. Further east, the detachment would ramp down to a 7-km-deep detachment, allowing the E-dipping Lungchuan thrust and Pingxi thrust to bring Miocene formations to the surface. Another ramp from 7 to 11-km depth, is expected further east to bring the slate belt to the surface. Coseismic surface deformation measurements suggest that, in addition to the deeper (15-20 km) main rupture plane, mostly the 4-7-km deep ramp, the Lungchuan back-thrust, and the Tainan detachment slipped aseismically during or right after the earthquake. Preliminary restorations show that the E-dipping Lungchuan thrust and Pingxi thrust consumed >10 km shortening each, while evidence for present-day tectonic activity remains to be found. By contrast, structures located west of the 4-7-km deep ramp accommodated all together <10 km shortening since 450 ka ago or less based on published nannostratigraphy, and they show numerous evidence of Late Quaternary and present-day activity. The restorations also allow connecting the 11-km-depth detachment to a main detachment level evidenced from a velocity inversion in the local tomography. By contrast, the

The Limit Deposit Velocity model, a new approach

Directory of Open Access Journals (Sweden)

Miedema Sape A.

2015-12-01

Full Text Available In slurry transport of settling slurries in Newtonian fluids, it is often stated that one should apply a line speed above a critical velocity, because blow this critical velocity there is the danger of plugging the line. There are many definitions and names for this critical velocity. It is referred to as the velocity where a bed starts sliding or the velocity above which there is no stationary bed or sliding bed. Others use the velocity where the hydraulic gradient is at a minimum, because of the minimum energy consumption. Most models from literature are one term one equation models, based on the idea that the critical velocity can be explained that way.

Higher education delays and shortens cognitive impairment: a multistate life table analysis of the US Health and Retirement Study

NARCIS (Netherlands)

Reuser, M.; Willekens, F.J.C.; Bonneux, L.G.A.

2011-01-01

Improved health may extend or shorten the duration of cognitive impairment by postponing incidence or death. We assess the duration of cognitive impairment in the US Health and Retirement Study (1992–2004) by self reported BMI, smoking and levels of education in men and women and three ethnic

Higher education delays and shortens cognitive impairment : A multistate life table analysis of the US Health and Retirement Study

NARCIS (Netherlands)

Reuser, Mieke; Willekens, Frans J.; Bonneux, Luc

Improved health may extend or shorten the duration of cognitive impairment by postponing incidence or death. We assess the duration of cognitive impairment in the US Health and Retirement Study (1992-2004) by self reported BMI, smoking and levels of education in men and women and three ethnic

Rayleigh wave group velocity and shear wave velocity structure in the San Francisco Bay region from ambient noise tomography

Science.gov (United States)

Li, Peng; Thurber, Clifford

2018-06-01

We derive new Rayleigh wave group velocity models and a 3-D shear wave velocity model of the upper crust in the San Francisco Bay region using an adaptive grid ambient noise tomography algorithm and 6 months of continuous seismic data from 174 seismic stations from multiple networks. The resolution of the group velocity models is 0.1°-0.2° for short periods (˜3 s) and 0.3°-0.4° for long periods (˜10 s). The new shear wave velocity model of the upper crust reveals a number of important structures. We find distinct velocity contrasts at the Golden Gate segment of the San Andreas Fault, the West Napa Fault, central part of the Hayward Fault and southern part of the Calaveras Fault. Low shear wave velocities are mainly located in Tertiary and Quaternary basins, for instance, La Honda Basin, Livermore Valley and the western and eastern edges of Santa Clara Valley. Low shear wave velocities are also observed at the Sonoma volcanic field. Areas of high shear wave velocity include the Santa Lucia Range, the Gabilan Range and Ben Lomond Plutons, and the Diablo Range, where Franciscan Complex or Silinian rocks are exposed.

A Simple Piece of Apparatus to Aid the Understanding of the Relationship between Angular Velocity and Linear Velocity

Science.gov (United States)

Unsal, Yasin

2011-01-01

One of the subjects that is confusing and difficult for students to fully comprehend is the concept of angular velocity and linear velocity. It is the relationship between linear and angular velocity that students find difficult; most students understand linear motion in isolation. In this article, we detail the design, construction and…

Peculiar velocity measurement in a clumpy universe

Science.gov (United States)

Habibi, Farhang; Baghram, Shant; Tavasoli, Saeed

Aims: In this work, we address the issue of peculiar velocity measurement in a perturbed Friedmann universe using the deviations from measured luminosity distances of standard candles from background FRW universe. We want to show and quantify the statement that in intermediate redshifts (0.5 deviations from the background FRW model are not uniquely governed by peculiar velocities. Luminosity distances are modified by gravitational lensing. We also want to indicate the importance of relativistic calculations for peculiar velocity measurement at all redshifts. Methods: For this task, we discuss the relativistic correction on luminosity distance and redshift measurement and show the contribution of each of the corrections as lensing term, peculiar velocity of the source and Sachs-Wolfe effect. Then, we use the SNe Ia sample of Union 2, to investigate the relativistic effects, we consider. Results: We show that, using the conventional peculiar velocity method, that ignores the lensing effect, will result in an overestimate of the measured peculiar velocities at intermediate redshifts. Here, we quantify this effect. We show that at low redshifts the lensing effect is negligible compare to the effect of peculiar velocity. From the observational point of view, we show that the uncertainties on luminosity of the present SNe Ia data prevent us from precise measuring the peculiar velocities even at low redshifts (z < 0.2).

Introduction to vector velocity imaging

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt; Udesen, Jesper; Hansen, Kristoffer Lindskov

Current ultrasound scanners can only estimate the velocity along the ultrasound beam and this gives rise to the cos() factor on all velocity estimates. This is a major limitation as most vessels are close to perpendicular to the beam. Also the angle varies as a function of space and time making ...

Mechanical versus kinematical shortening reconstructions of the Zagros High Folded Zone (Kurdistan region of Iraq)

Science.gov (United States)

Frehner, Marcel; Reif, Daniel; Grasemann, Bernhard

2012-06-01

This paper compares kinematical and mechanical techniques for the palinspastic reconstruction of folded cross sections in collision orogens. The studied area and the reconstructed NE-SW trending, 55.5 km long cross section is located in the High Folded Zone of the Zagros fold-and-thrust belt in the Kurdistan region of Iraq. The present-day geometry of the cross section has been constructed from field as well as remote sensing data. In a first step, the structures and the stratigraphy are simplified and summarized in eight units trying to identify the main geometric and mechanical parameters. In a second step, the shortening is kinematically estimated using the dip domain method to 11%-15%. Then the same cross section is used in a numerical finite element model to perform dynamical unfolding simulations taking various rheological parameters into account. The main factor allowing for an efficient dynamic unfolding is the presence of interfacial slip conditions between the mechanically strong units. Other factors, such as Newtonian versus power law viscous rheology or the presence of a basement, affect the numerical simulations much less strongly. If interfacial slip is accounted for, fold amplitudes are reduced efficiently during the dynamical unfolding simulations, while welded layer interfaces lead to unrealistic shortening estimates. It is suggested that interfacial slip and decoupling of the deformation along detachment horizons is an important mechanical parameter that controlled the folding processes in the Zagros High Folded Zone.

Influence of Velocity on Variability in Gait Kinematics

DEFF Research Database (Denmark)

Yang, Sylvia X M; Larsen, Peter K; Alkjær, Tine

2014-01-01

the concurrence of joint angles throughout a gait cycle at three different velocities (3.0, 4.5, 6.0 km/h). Six datasets at each velocity were collected from 16 men. A variability range VR throughout the gait cycle at each velocity for each joint angle for each person was calculated. The joint angles at each...... velocity were compared pairwise, and whenever this showed values within the VR of this velocity, the case was positive. By adding the positives throughout the gait cycle, phases with high and low concurrences were located; peak concurrence was observed at mid-stance phase. Striving for the same velocity...

Modified circular velocity law

Science.gov (United States)

Djeghloul, Nazim

2018-05-01

A modified circular velocity law is presented for a test body orbiting around a spherically symmetric mass. This law exhibits a distance scale parameter and allows to recover both usual Newtonian behaviour for lower distances and a constant velocity limit at large scale. Application to the Galaxy predicts the known behaviour and also leads to a galactic mass in accordance with the measured visible stellar mass so that additional dark matter inside the Galaxy can be avoided. It is also shown that this circular velocity law can be embedded in a geometrical description of spacetime within the standard general relativity framework upon relaxing the usual asymptotic flatness condition. This formulation allows to redefine the introduced Newtonian scale limit in term of the central mass exclusively. Moreover, a satisfactory answer to the galactic escape speed problem can be provided indicating the possibility that one can also get rid of dark matter halo outside the Galaxy.

Onset of decreased heart work is correlated with increased heart rate and shortened QT interval in high-carbohydrate fed overweight rats.

Science.gov (United States)

Durak, Aysegul; Olgar, Yusuf; Tuncay, Erkan; Karaomerlioglu, Irem; Kayki Mutlu, Gizem; Arioglu Inan, Ebru; Altan, Vecdi Melih; Turan, Belma

2017-11-01

Mechanical activity of the heart is adversely affected in metabolic syndrome (MetS) characterized by increased body mass and marked insulin resistance. Herein, we examined the effects of high carbohydrate intake on cardiac function abnormalities by evaluating in situ heart work, heart rate, and electrocardiograms (ECGs) in rats. MetS was induced in male Wistar rats by adding 32% sucrose to drinking water for 22-24 weeks and was confirmed by insulin resistance, increased body weight, increased blood glucose and serum insulin, and increased systolic and diastolic blood pressures in addition to significant loss of left ventricular integrity and increased connective tissue around myofibrils. Analysis of in situ ECG recordings showed a markedly shortened QT interval and decreased QRS amplitude with increased heart rate. We also observed increased oxidative stress and decreased antioxidant defense characterized by decreases in serum total thiol level and attenuated paraoxonase and arylesterase activities. Our data indicate that increased heart rate and a shortened QT interval concomitant with higher left ventricular developed pressure in response to β-adrenoreceptor stimulation as a result of less cyclic AMP release could be regarded as a natural compensation mechanism in overweight rats with MetS. In addition to the persistent insulin resistance and obesity associated with MetS, one should consider the decreased heart work, increased heart rate, and shortened QT interval associated with high carbohydrate intake, which may have more deleterious effects on the mammalian heart.

14 CFR 29.87 - Height-velocity envelope.

Science.gov (United States)

2010-01-01

... Category A engine isolation requirements, the height-velocity envelope for complete power failure must be... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Height-velocity envelope. 29.87 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Performance § 29.87 Height-velocity envelope. (a...

Déjà Experiences in Temporal Lobe Epilepsy

OpenAIRE

Illman, Nathan A.; Butler, Chris R.; Souchay, Celine; Moulin, Chris J. A.

2012-01-01

Historically, déjà vu has been linked to seizure activity in temporal lobe epilepsy, and clinical reports suggest that many patients experience the phenomenon as a manifestation of simple partial seizures. We review studies on déjà vu in epilepsy with reference to recent advances in the understanding of déjà vu from a cognitive and neuropsychological standpoint. We propose a decoupled familiarity hypothesis, whereby déjà vu is produced by an erroneous feeling of familiarity which is not in ...

Detonation velocity in poorly mixed gas mixtures

Science.gov (United States)

Prokhorov, E. S.

2017-10-01

The technique for computation of the average velocity of plane detonation wave front in poorly mixed mixture of gaseous hydrocarbon fuel and oxygen is proposed. Here it is assumed that along the direction of detonation propagation the chemical composition of the mixture has periodic fluctuations caused, for example, by layered stratification of gas charge. The technique is based on the analysis of functional dependence of ideal (Chapman-Jouget) detonation velocity on mole fraction (with respect to molar concentration) of the fuel. It is shown that the average velocity of detonation can be significantly (by more than 10%) less than the velocity of ideal detonation. The dependence that permits to estimate the degree of mixing of gas mixture basing on the measurements of average detonation velocity is established.

Velocity navigator for motion compensated thermometry.

Science.gov (United States)

Maier, Florian; Krafft, Axel J; Yung, Joshua P; Stafford, R Jason; Elliott, Andrew; Dillmann, Rüdiger; Semmler, Wolfhard; Bock, Michael

2012-02-01

Proton resonance frequency shift thermometry is sensitive to breathing motion that leads to incorrect phase differences. In this work, a novel velocity-sensitive navigator technique for triggering MR thermometry image acquisition is presented. A segmented echo planar imaging pulse sequence was modified for velocity-triggered temperature mapping. Trigger events were generated when the estimated velocity value was less than 0.2 cm/s during the slowdown phase in parallel to the velocity-encoding direction. To remove remaining high-frequency spikes from pulsation in real time, a Kalman filter was applied to the velocity navigator data. A phantom experiment with heating and an initial volunteer experiment without heating were performed to show the applicability of this technique. Additionally, a breath-hold experiment was conducted for comparison. A temperature rise of ΔT = +37.3°C was seen in the phantom experiment, and a root mean square error (RMSE) outside the heated region of 2.3°C could be obtained for periodic motion. In the volunteer experiment, a RMSE of 2.7°C/2.9°C (triggered vs. breath hold) was measured. A novel velocity navigator with Kalman filter postprocessing in real time significantly improves the temperature accuracy over non-triggered acquisitions and suggests being comparable to a breath-held acquisition. The proposed technique might be clinically applied for monitoring of thermal ablations in abdominal organs.

Effect of a 17 day spaceflight on contractile properties of human soleus muscle fibres

Science.gov (United States)

Widrick, J. J.; Knuth, S. T.; Norenberg, K. M.; Romatowski, J. G.; Bain, J. L.; Riley, D. A.; Karhanek, M.; Trappe, S. W.; Trappe, T. A.; Costill, D. L.;

ROTATIONAL VELOCITIES FOR M DWARFS

International Nuclear Information System (INIS)

Jenkins, J. S.; Ramsey, L. W.; Jones, H. R. A.; Pavlenko, Y.; Barnes, J. R.; Pinfield, D. J.; Gallardo, J.

2009-01-01

We present spectroscopic rotation velocities (v sin i) for 56 M dwarf stars using high-resolution Hobby-Eberly Telescope High Resolution Spectrograph red spectroscopy. In addition, we have also determined photometric effective temperatures, masses, and metallicities ([Fe/H]) for some stars observed here and in the literature where we could acquire accurate parallax measurements and relevant photometry. We have increased the number of known v sin i values for mid M stars by around 80% and can confirm a weakly increasing rotation velocity with decreasing effective temperature. Our sample of v sin is peak at low velocities (∼3 km s -1 ). We find a change in the rotational velocity distribution between early M and late M stars, which is likely due to the changing field topology between partially and fully convective stars. There is also a possible further change in the rotational distribution toward the late M dwarfs where dust begins to play a role in the stellar atmospheres. We also link v sin i to age and show how it can be used to provide mid-M star age limits. When all literature velocities for M dwarfs are added to our sample, there are 198 with v sin i ≤ 10 km s -1 and 124 in the mid-to-late M star regime (M3.0-M9.5) where measuring precision optical radial velocities is difficult. In addition, we also search the spectra for any significant Hα emission or absorption. Forty three percent were found to exhibit such emission and could represent young, active objects with high levels of radial-velocity noise. We acquired two epochs of spectra for the star GJ1253 spread by almost one month and the Hα profile changed from showing no clear signs of emission, to exhibiting a clear emission peak. Four stars in our sample appear to be low-mass binaries (GJ1080, GJ3129, Gl802, and LHS3080), with both GJ3129 and Gl802 exhibiting double Hα emission features. The tables presented here will aid any future M star planet search target selection to extract stars with low v

Propagation Velocity of Solid Earth Tides

Science.gov (United States)

Pathak, S.

2017-12-01

One of the significant considerations in most of the geodetic investigations is to take into account the outcome of Solid Earth tides on the location and its consequent impact on the time series of coordinates. In this research work, the propagation velocity resulting from the Solid Earth tides between the Indian stations is computed. Mean daily coordinates for the stations have been computed by applying static precise point positioning technique for a day. The computed coordinates are used as an input for computing the tidal displacements at the stations by Gravity method along three directions at 1-minute interval for 24 hours. Further the baseline distances are computed between four Indian stations. Computation of the propagation velocity for Solid Earth tides can be done by the virtue of study of the concurrent effect of it in-between the stations of identified baseline distance along with the time consumed by the tides for reaching from one station to another. The propagation velocity helps in distinguishing the impact at any station if the consequence at a known station for a specific time-period is known. Thus, with the knowledge of propagation velocity, the spatial and temporal effects of solid earth tides can be estimated with respect to a known station. As theoretically explained, the tides generated are due to the position of celestial bodies rotating about Earth. So the need of study is to observe the correlation of propagation velocity with the rotation speed of the Earth. The propagation velocity of Solid Earth tides comes out to be in the range of 440-470 m/s. This velocity comes out to be in a good agreement with the Earth's rotation speed.

Metabolic and molecular analyses of white mutant Vaccinium berries show down-regulation of MYBPA1-type R2R3 MYB regulatory factor.

Science.gov (United States)

Primetta, Anja K; Karppinen, Katja; Riihinen, Kaisu R; Jaakola, Laura

2015-09-01

MYBPA1-type R2R3 MYB transcription factor shows down-regulation in white mutant berries of Vaccinium uliginosum deficient in anthocyanins but not proanthocyanidins suggesting a role in the regulation of anthocyanin biosynthesis. Berries of the genus Vaccinium are among the best natural sources of flavonoids. In this study, the expression of structural and regulatory flavonoid biosynthetic genes and the accumulation of flavonoids in white mutant and blue-colored wild-type bog bilberry (V. uliginosum) fruits were measured at different stages of berry development. In contrast to high contents of anthocyanins in ripe blue-colored berries, only traces were detected by HPLC-ESI-MS in ripe white mutant berries. However, similar profile and high levels of flavonol glycosides and proanthocyanidins were quantified in both ripe white and ripe wild-type berries. Analysis with qRT-PCR showed strong down-regulation of structural genes chalcone synthase (VuCHS), dihydroflavonol 4-reductase (VuDFR) and anthocyanidin synthase (VuANS) as well as MYBPA1-type transcription factor VuMYBPA1 in white berries during ripening compared to wild-type berries. The profiles of transcript accumulation of chalcone isomerase (VuCHI), anthocyanidin reductase (VuANR), leucoanthocyanidin reductase (VuLAR) and flavonoid 3'5' hydroxylase (VuF3'5'H) were more similar between the white and the wild-type berries during fruit development, while expression of UDP-glucose: flavonoid 3-O-glucosyltransferase (VuUFGT) showed similar trend but fourfold lower level in white mutant. VuMYBPA1, the R2R3 MYB family member, is a homologue of VmMYB2 of V. myrtillus and VcMYBPA1 of V. corymbosum and belongs to MYBPA1-type MYB family which members are shown in some species to be related with proanthocyanidin biosynthesis in fruits. Our results combined with earlier data of the role of VmMYB2 in white mutant berries of V. myrtillus suggest that the regulation of anthocyanin biosynthesis in Vaccinium species could differ

The species velocity of trees in Alaska

Science.gov (United States)

Morrison, B. D.; Napier, J.; de Lafontaine, G.; Heath, K.; Li, B.; Hu, F.; Greenberg, J. A.

2017-12-01

Anthropogenic climate change has motivated interest in the paleo record to enhance our knowledge about past vegetation responses to climate change and help understand potential responses in the future. Additionally, polar regions currently experience the most rapid rates of climate change globally, prompting concern over changes in the ecological composition of high latitude ecosystems. Recent analyses have attempted to construct methods to estimate a species' ability to track climate change by computing climate velocity; a measure of the rate of climate displacement across a landscape which may indicate the speed an organism must migrate to keep pace with climate change. However, a challenge to using climate velocity in understanding range shifts is a lack of species-specificity in the velocity calculations: climate velocity does not actually use any species data in its analysis. To solve the shortcomings of climate velocity in estimating species displacement rates, we computed the "species velocity" of white spruce, green and grey alder populations across the state of Alaska from the Last Glacial Maximum (LGM) to today. Species velocity represents the rate and direction a species is required to migrate to keep pace with a changing climate following the LGM. We used a species distribution model to determine past and present white spruce and alder distributions using statistically downscaled climate data at 60m. Species velocity was then derived from the change in species distribution per year by the change in distribution over Alaska (km/yr). High velocities indicate locations where the species environmental envelope is changing drastically and must disperse rapidly to survive climate change. As a result, high velocity regions are more vulnerable to distribution shifts and higher risk of local extinction. Conversely, low species velocities indicate locations where the local climate envelope is shifting relatively slowly, reducing the stress to disperse quickly

Middle cerebral artery blood velocity during running

DEFF Research Database (Denmark)

Lyngeraa, Tobias; Pedersen, Lars Møller; Mantoni, T

2013-01-01

for eight subjects, respectively, were excluded from analysis because of insufficient signal quality. Running increased mean arterial pressure and mean MCA velocity and induced rhythmic oscillations in BP and in MCA velocity corresponding to the difference between step rate and heart rate (HR) frequencies....... During running, rhythmic oscillations in arterial BP induced by interference between HR and step frequency impact on cerebral blood velocity. For the exercise as a whole, average MCA velocity becomes elevated. These results suggest that running not only induces an increase in regional cerebral blood flow...

Predicting vertical jump height from bar velocity.

Science.gov (United States)

García-Ramos, Amador; Štirn, Igor; Padial, Paulino; Argüelles-Cienfuegos, Javier; De la Fuente, Blanca; Strojnik, Vojko; Feriche, Belén

2015-06-01

The objective of the study was to assess the use of maximum (Vmax) and final propulsive phase (FPV) bar velocity to predict jump height in the weighted jump squat. FPV was defined as the velocity reached just before bar acceleration was lower than gravity (-9.81 m·s(-2)). Vertical jump height was calculated from the take-off velocity (Vtake-off) provided by a force platform. Thirty swimmers belonging to the National Slovenian swimming team performed a jump squat incremental loading test, lifting 25%, 50%, 75% and 100% of body weight in a Smith machine. Jump performance was simultaneously monitored using an AMTI portable force platform and a linear velocity transducer attached to the barbell. Simple linear regression was used to estimate jump height from the Vmax and FPV recorded by the linear velocity transducer. Vmax (y = 16.577x - 16.384) was able to explain 93% of jump height variance with a standard error of the estimate of 1.47 cm. FPV (y = 12.828x - 6.504) was able to explain 91% of jump height variance with a standard error of the estimate of 1.66 cm. Despite that both variables resulted to be good predictors, heteroscedasticity in the differences between FPV and Vtake-off was observed (r(2) = 0.307), while the differences between Vmax and Vtake-off were homogenously distributed (r(2) = 0.071). These results suggest that Vmax is a valid tool for estimating vertical jump height in a loaded jump squat test performed in a Smith machine. Key pointsVertical jump height in the loaded jump squat can be estimated with acceptable precision from the maximum bar velocity recorded by a linear velocity transducer.The relationship between the point at which bar acceleration is less than -9.81 m·s(-2) and the real take-off is affected by the velocity of movement.Mean propulsive velocity recorded by a linear velocity transducer does not appear to be optimal to monitor ballistic exercise performance.

Options for shortening nuclear power plant refueling outages

International Nuclear Information System (INIS)

Kastl, H.

2001-01-01

Deregulation of the European electricity market on 01.01.1999 forced a large number of electric utilities- especially nuclear power plant operators - to find ways of drastically cutting down their costs in order to be able to compete successfully within the new market environment. Nuclear power plants currently in operation mainly have three potential ways of reducing their power generating costs: by increasing plant availability, reducing fuel costs and cutting down operating costs. The optimization of plant refueling outages offers considerable potential for enhancing plant availability, but also helps bring down operating costs by reducing expenditure on maintenance. In order to optimize an outage in terms of its duration and costs, a variety of approaches are possible - all of which, however, involve certain key factors such as good organization, planning, logistics and control, improvement of equipment and tools, as well as motivation of personnel. Another aspect is the introduction of innovative technologies. In the last few years, such technologies have frequently enabled maintenance effort to be reduced, thus saving considerable time, and have also resulted in a need for fewer personnel to carry out the work, thus reducing radiation exposure. In many instances they have also improved the quality of work and outage performance as a whole. The paper uses recent examples to show how innovative technologies can contribute to-wards reducing nuclear plant maintenance costs and shorten the duration of refueling out-ages. (author)

Chemical Sharpening, Shortening, and Unzipping of Boron Nitride Nanotubes

Science.gov (United States)

Liao, Yunlong; Chen, Zhongfang; Connell, John W.; Fay, Catharine C.; Park, Cheol; Kim, Jae-Woo; Lin, Yi

2014-01-01

Boron nitride nanotubes (BNNTs), the one-dimensional member of the boron nitride nanostructure family, are generally accepted to be highly inert to oxidative treatments and can only be covalently modifi ed by highly reactive species. Conversely, it is discovered that the BNNTs can be chemically dispersed and their morphology modifi ed by a relatively mild method: simply sonicating the nanotubes in aqueous ammonia solution. The dispersed nanotubes are significantly corroded, with end-caps removed, tips sharpened, and walls thinned. The sonication treatment in aqueous ammonia solution also removes amorphous BN impurities and shortened BNNTs, resembling various oxidative treatments of carbon nanotubes. Importantly, the majority of BNNTs are at least partially longitudinally cut, or "unzipped". Entangled and freestanding BN nanoribbons (BNNRs), resulting from the unzipping, are found to be approximately 5-20 nm in width and up to a few hundred nanometers in length. This is the fi rst chemical method to obtain BNNRs from BNNT unzipping. This method is not derived from known carbon nanotube unzipping strategies, but is unique to BNNTs because the use of aqueous ammonia solutions specifi cally targets the B-N bond network. This study may pave the way for convenient processing of BNNTs, previously thought to be highly inert, toward controlling their dispersion, purity, lengths, and electronic properties.

The Mini-OAKHQOL for knee and hip osteoarthritis quality of life was obtained following recent shortening guidelines.

Science.gov (United States)

Guillemin, Francis; Rat, Anne-Christine; Goetz, Christophe; Spitz, Elisabeth; Pouchot, Jacques; Coste, Joël

2016-01-01

To develop a short form of the knee and hip osteoarthritis quality of life questionnaire, the Mini-OAKHQOL, preserving the conceptual model and, as far as possible, the content and the psychometric properties of the original instrument. A two-step shortening procedure was used: (1) a consensus Delphi method, with a panel of patients and another of professionals independently asked to select items and (2) a nominal group, where patients, professionals, and methodologists reached consensus on the final selection of items, using information from the panels and from modern measurement and classical test theory analyses. The psychometric properties of the Mini-OAKHQOL were assessed in an independent population-based sample of 581 subjects with knee or hip osteoarthritis. The two-step shortening procedure resulted in a 20-item questionnaire. Confirmatory factor analysis showed preservation of the original five-dimensional structure. Rasch analyses showed the unidimensionality and invariance by sex, age, and joint of the main dimensions. Convergent validity, reproducibility, and internal consistency were similar to or better than those of the original OAKHQOL. The 20-item Mini-OAKHQOL has good psychometric properties and can be used for the measurement of quality of life in subjects with osteoarthritis of the lower limbs. Copyright © 2016 Elsevier Inc. All rights reserved.

Radiation and chemotherapy bystander effects induce early genomic instability events: telomere shortening and bridge formation coupled with mitochondrial dysfunction.

LENUS (Irish Health Repository)

Gorman, Sheeona

2012-02-01

The bridge breakage fusion cycle is a chromosomal instability mechanism responsible for genomic changes. Radiation bystander effects induce genomic instability; however, the mechanism driving this instability is unknown. We examined if radiation and chemotherapy bystander effects induce early genomic instability events such as telomere shortening and bridge formation using a human colon cancer explant model. We assessed telomere lengths, bridge formations, mitochondrial membrane potential and levels of reactive oxygen species in bystander cells exposed to medium from irradiated and chemotherapy-treated explant tissues. Bystander cells exposed to media from 2Gy, 5Gy, FOLFOX treated tumor and matching normal tissue showed a significant reduction in telomere lengths (all p values <0.018) and an increase in bridge formations (all p values <0.017) compared to bystander cells treated with media from unirradiated tissue (0Gy) at 24h. There was no significant difference between 2Gy and 5Gy treatments, or between effects elicited by tumor versus matched normal tissue. Bystander cells exposed to media from 2Gy irradiated tumor tissue showed significant depolarisation of the mitochondrial membrane potential (p=0.012) and an increase in reactive oxygen species levels. We also used bystander cells overexpressing a mitochondrial antioxidant manganese superoxide dismutase (MnSOD) to examine if this antioxidant could rescue the mitochondrial changes and subsequently influence nuclear instability events. In MnSOD cells, ROS levels were reduced (p=0.02) and mitochondrial membrane potential increased (p=0.04). These events were coupled with a decrease in percentage of cells with anaphase bridges and a decrease in the number of cells undergoing telomere length shortening (p values 0.01 and 0.028 respectively). We demonstrate that radiation and chemotherapy bystander responses induce early genomic instability coupled with defects in mitochondrial function. Restoring mitochondrial

The effect of fog on radionuclide deposition velocities

International Nuclear Information System (INIS)

Gibb, R.; Carson, P.; Thompson, W.

1997-01-01

Current nuclear power station release models do not evaluate deposition under foggy atmospheric conditions. Deposition velocities and scavenging coefficients of radioactive particles entrained in fog are presented for the Point Lepreau area of the Bay of Fundy coast. It is recommended to calculate deposition based on fog deposition velocities. The deposition velocities can be calculated from common meteorological data. The range of deposition velocities is approximately 1 - 100 cm/s. Fog deposition is surface roughness dependent with forests having larger deposition and deposition velocities than soil or grasses. (author)

Life shortening, tumor induction, and tissue dose for fission-neutron and gamma-ray irradiations

International Nuclear Information System (INIS)

Grahn, D.; Duggal, K.; Lombard, L.S.

1985-01-01

The primary focus of this program is to obtain information on the late effects of whole body exposure to low doses of a high linear-energy-transfer (LET) and a low-LET ionizing radiation in experimental animals to provide guidance for the prediction of radiation hazards to man. The information obtained takes the form of dose-response curves for life shortening and for the induction of numerous specific types of tumors. The animals are irradiated with fission neutrons from the Janus reactor and with 60 Co gamma rays, delivered as single, weekly, or duration-of-life exposures covering the range of doses and dose rates. 6 refs

Characterization of the seismically imaged Tuscarora fold system and implications for layer parallel shortening in the Pennsylvania salient

Science.gov (United States)

Mount, Van S.; Wilkins, Scott; Comiskey, Cody S.

2017-12-01

The Tuscarora fold system (TFS) is located in the Pennsylvania salient in the foreland of the Valley and Ridge province. The TFS is imaged in high quality 3D seismic data and comprises a system of small-scale folds within relatively flat-lying Lower Silurian Tuscarora Formation strata. We characterize the TFS structures and infer layer parallel shortening (LPS) directions and magnitudes associated with deformation during the Alleghany Orogeny. Previously reported LPS data in our study area are from shallow Devonian and Carboniferous strata (based on outcrop and core analyses) above the shallowest of three major detachments recognized in the region. Seismic data allows us to characterize LPS at depth in strata beneath the shallow detachment. Our LPS data (orientations and inferred magnitudes) are consistent with the shallow data leading us to surmise that LPS during Alleghanian deformation fanned around the salient and was distributed throughout the stratigraphic section - and not isolated to strata above the shallow detachment. We propose that a NW-SE oriented Alleghanian maximum principal stress was perturbed by deep structure associated with the non-linear margin of Laurentia resulting in fanning of shortening directions within the salient.

Balance velocities of the Greenland ice sheet

DEFF Research Database (Denmark)

Joughin, I.; Fahnestock, M.; Ekholm, Simon

1997-01-01

We present a map of balance velocities for the Greenland ice sheet. The resolution of the underlying DEM, which was derived primarily from radar altimetery data, yields far greater detail than earlier balance velocity estimates for Greenland. The velocity contours reveal in striking detail......, the balance map is useful for ice-sheet modelling, mass balance studies, and field planning....

Optimal velocity difference model for a car-following theory

International Nuclear Information System (INIS)

Peng, G.H.; Cai, X.H.; Liu, C.Q.; Cao, B.F.; Tuo, M.X.

2011-01-01

In this Letter, we present a new optimal velocity difference model for a car-following theory based on the full velocity difference model. The linear stability condition of the new model is obtained by using the linear stability theory. The unrealistically high deceleration does not appear in OVDM. Numerical simulation of traffic dynamics shows that the new model can avoid the disadvantage of negative velocity occurred at small sensitivity coefficient λ in full velocity difference model by adjusting the coefficient of the optimal velocity difference, which shows that collision can disappear in the improved model. -- Highlights: → A new optimal velocity difference car-following model is proposed. → The effects of the optimal velocity difference on the stability of traffic flow have been explored. → The starting and braking process were carried out through simulation. → The effects of the optimal velocity difference can avoid the disadvantage of negative velocity.

Velocity measurement of conductor using electromagnetic induction

International Nuclear Information System (INIS)

Kim, Gu Hwa; Kim, Ho Young; Park, Joon Po; Jeong, Hee Tae; Lee, Eui Wan

2002-01-01

A basic technology was investigated to measure the speed of conductor by non-contact electromagnetic method. The principle of the velocity sensor was electromagnetic induction. To design electromagnet for velocity sensor, 2D electromagnetic analysis was performed using FEM software. The sensor output was analyzed according to the parameters of velocity sensor, such as the type of magnetizing currents and the lift-off. Output of magnetic sensor was linearly depended on the conductor speed and magnetizing current. To compensate the lift-off changes during measurement of velocity, the other magnetic sensor was put at the pole of electromagnet.

Normal Patterns of Deja Experience in a Healthy, Blind Male: Challenging Optical Pathway Delay Theory

Science.gov (United States)

O'Connor, Akira R.; Moulin, Christopher J. A.

2006-01-01

We report the case of a 25-year-old healthy, blind male, MT, who experiences normal patterns of deja vu. The optical pathway delay theory of deja vu formation assumes that neuronal input from the optical pathways is necessary for the formation of the experience. Surprisingly, although the sensation of deja vu is known to be experienced by blind…

Neogene shortening and exhumation of the Zagros fold-thrust belt and foreland basin in the Kurdistan region of northern Iraq

Science.gov (United States)

Koshnaw, Renas I.; Horton, Brian K.; Stockli, Daniel F.; Barber, Douglas E.; Tamar-Agha, Mazin Y.; Kendall, Jerome J.

2017-01-01

The Zagros fold-thrust belt in the Kurdistan region of Iraq encroached southward toward a rapidly subsiding Neogene foreland basin and was later partitioned by out-of-sequence shortening focused along the Mountain Front Flexure (MFF), as defined by new low-temperature thermochronologic, stratigraphic, and provenance results. Apatite (U-Th)/He ages document rapid deformation advance from the Main Zagros Fault to southern frontal structures (Kirkuk, Shakal, and Qamar thrusts) at 10-8 Ma, followed by potential basement-involved out-of-sequence development of the MFF (Qaradagh anticline) by 5 Ma. Distinct shifts in detrital zircon U-Pb provenance signatures for Neogene foreland basin fill provide evidence for drainage reorganization during fold-thrust belt advance. U-Pb age spectra and petrologic data from the Injana (Upper Fars) Formation indicate derivation from a variety of Eurasian, Pan-African, ophiolitic and Mesozoic-Cenozoic volcanic terranes, whereas the Mukdadiya (Lower Bakhtiari) and Bai-Hasan (Upper Bakhtiari) Formations show nearly exclusive derivation from the Paleogene Walash-Naopurdan volcanic complex near the Iraq-Iran border. Such a sharp cutoff in Eurasian, Pan-African, and ophiolitic sources is likely associated with drainage reorganization and tectonic development of the geomorphic barrier formed by the MFF. As a result of Zagros crustal shortening, thickening and loading, the Neogene foreland basin developed and accommodated an abrupt influx of fluvial clastic sediment that contains growth stratal evidence of synkinematic accumulation. The apparent out-of-sequence pattern of upper crustal shortening in the hinterland to foreland zone of Iraqi Kurdistan suggests that structural inheritance and the effects of synorogenic erosion and accumulation are important factors influencing the irregular and episodic nature of orogenic growth in the Zagros.

Cognitive regulation of saccadic velocity by reward prospect.

Science.gov (United States)

Chen, Lewis L; Hung, Leroy Y; Quinet, Julie; Kosek, Kevin

2013-08-01

It is known that expectation of reward speeds up saccades. Past studies have also shown the presence of a saccadic velocity bias in the orbit, resulting from a biomechanical regulation over varying eccentricities. Nevertheless, whether and how reward expectation interacts with the biomechanical regulation of saccadic velocities over varying eccentricities remains unknown. We addressed this question by conducting a visually guided double-step saccade task. The role of reward expectation was tested in monkeys performing two consecutive horizontal saccades, one associated with reward prospect and the other not. To adequately assess saccadic velocity and avoid adaptation, we systematically varied initial eye positions, saccadic directions and amplitudes. Our results confirmed the existence of a velocity bias in the orbit, i.e., saccadic peak velocity decreased linearly as the initial eye position deviated in the direction of the saccade. The slope of this bias increased as saccadic amplitudes increased. Nevertheless, reward prospect facilitated velocity to a greater extent for saccades away from than for saccades toward the orbital centre, rendering an overall reduction in the velocity bias. The rate (slope) and magnitude (intercept) of reward modulation over this velocity bias were linearly correlated with amplitudes, similar to the amplitude-modulated velocity bias without reward prospect, which presumably resulted from a biomechanical regulation. Small-amplitude (≤ 5°) saccades received little modulation. These findings together suggest that reward expectation modulated saccadic velocity not as an additive signal but as a facilitating mechanism that interacted with the biomechanical regulation. © 2013 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Global Plate Velocities from the Global Positioning System

Science.gov (United States)

Larson, Kristine M.; Freymueller, Jeffrey T.; Philipsen, Steven

1997-01-01

We have analyzed 204 days of Global Positioning System (GPS) data from the global GPS network spanning January 1991 through March 1996. On the basis of these GPS coordinate solutions, we have estimated velocities for 38 sites, mostly located on the interiors of the Africa, Antarctica, Australia, Eurasia, Nazca, North America, Pacific, and South America plates. The uncertainties of the horizontal velocity components range from 1.2 to 5.0 mm/yr. With the exception of sites on the Pacific and Nazca plates, the GPS velocities agree with absolute plate model predictions within 95% confidence. For most of the sites in North America, Antarctica, and Eurasia, the agreement is better than 2 mm/yr. We find no persuasive evidence for significant vertical motions (less than 3 standard deviations), except at four sites. Three of these four were sites constrained to geodetic reference frame velocities. The GPS velocities were then used to estimate angular velocities for eight tectonic plates. Absolute angular velocities derived from the GPS data agree with the no net rotation (NNR) NUVEL-1A model within 95% confidence except for the Pacific plate. Our pole of rotation for the Pacific plate lies 11.5 deg west of the NNR NUVEL-1A pole, with an angular speed 10% faster. Our relative angular velocities agree with NUVEL-1A except for some involving the Pacific plate. While our Pacific-North America angular velocity differs significantly from NUVEL-1A, our model and NUVEL-1A predict very small differences in relative motion along the Pacific-North America plate boundary itself. Our Pacific-Australia and Pacific- Eurasia angular velocities are significantly faster than NUVEL-1A, predicting more rapid convergence at these two plate boundaries. Along the East Pacific Pise, our Pacific-Nazca angular velocity agrees in both rate and azimuth with NUVFL-1A.

Three dimensional reflection velocity analysis based on velocity model scan; Model scan ni yoru sanjigen hanshaha sokudo kaiseki

Energy Technology Data Exchange (ETDEWEB)

Minegishi, M; Tsuru, T [Japan National Oil Corp., Tokyo (Japan); Matsuoka, T [Japan Petroleum Exploration Corp., Tokyo (Japan)

1996-05-01

Introduced herein is a reflection wave velocity analysis method using model scanning as a method for velocity estimation across a section, the estimation being useful in the construction of a velocity structure model in seismic exploration. In this method, a stripping type analysis is carried out, wherein optimum structure parameters are determined for reflection waves one after the other beginning with those from shallower parts. During this process, the velocity structures previously determined for the shallower parts are fixed and only the lowest of the layers undergoing analysis at the time is subjected to model scanning. To consider the bending of ray paths at each velocity boundaries involving shallower parts, the ray path tracing method is utilized for the calculation of the reflection travel time curve for the reflection surface being analyzed. Out of the reflection wave travel time curves calculated using various velocity structure models, one that suits best the actual reflection travel time is detected. The degree of matching between the calculated result and actual result is measured by use of data semblance in a time window provided centering about the calculated reflective wave travel time. The structure parameter is estimated on the basis of conditions for the maximum semblance. 1 ref., 4 figs.

Cosmic string induced peculiar velocities

International Nuclear Information System (INIS)

van Dalen, A.; Schramm, D.N.

1987-02-01

We calculate analytically the probability distribution for peculiar velocities on scales from 10h -1 to 60h -1 Mpc with cosmic string loops as the dominant source of primordial gravitational perturbations. We consider a range of parameters βGμ appropriate for both hot (HDM) and cold (CDM) dark matter scenarios. An Ω = 1 CDM Universe is assumed with the loops randomly placed on a smooth background. It is shown how the effects can be estimated of loops breaking up and being born with a spectrum of sizes. It is found that to obtain large scale streaming velocities of at least 400 km/s it is necessary that either a large value for βGμ or the effect of loop fissioning and production details be considerable. Specifically, for optimal CDM string parameters Gμ = 10 -6 , β = 9, h = .5, and scales of 60h -1 Mpc, the parent size spectrum must be 36 times larger than the evolved daughter spectrum to achieve peculiar velocities of at least 400 km/s with a probability of 63%. With this scenario the microwave background dipole will be less than 800 km/s with only a 10% probability. The string induced velocity spectrum is relatively flat out to scales of about 2t/sub eq//a/sub eq/ and then drops off rather quickly. The flatness is a signature of string models of galaxy formation. With HDM a larger value of βGμ is necessary for galaxy formation since accretion on small scales starts later. Hence, with HDM, the peculiar velocity spectrum will be larger on large scales and the flat region will extend to larger scales. If large scale peculiar velocities greater than 400 km/s are real then it is concluded that strings plus CDM have difficulties. The advantages of strings plus HDM in this regard will be explored in greater detail in a later paper. 27 refs., 4 figs., 1 tab

Calcite Twinning in the Ordovician Martinsburg Formation, Delaware Water Gap, New Jersey, USA: Implications for Cleavage Formation and Tectonic Shortening in the Appalachian Piedmont Province

Directory of Open Access Journals (Sweden)

John P. Craddock

2016-02-01

Full Text Available A traverse across the Stone Church syncline in the Ordovician Martinsburg turbidites reveals an axial planar cleavage (N40°E, SE dips in regional thrust-related folds (N40°E, shallow plunges and five phases of sparry calcite. Calcite fillings are bedding-parallel, cleavage-parallel, and one vein set cross-cuts both earlier phases; the youngest calcite filling is a bedding-parallel fault gouge that crosscuts the cleavage and preserves top-down-to-the-southeast normal fault kinematics. Calcite veins unique to disharmonically-folded calcareous siltstones (Maxwell, 1962 were also analyzed. Stable isotopic analysis (O, C of all of the calcite phases indicates a uniform fluid source (δ13C −2.0, δ18O −13.3 VPDB and, potentially, a similar precipitation and mechanical twinning age. The twinning strains (n = 1341; average Δσ = −32 MPa; average ε1 = −2.9% in the calcite suite are consistent with SE-NW thrust shortening, and sub-horizontal shortening perpendicular to evolving axial planar cleavage planes in the Stone Church syncline. Calcareous siltstone layers within the Martinsburg Fm. turbidites share concordant bedding planes and are unique, chemically (XRF, but folded and cleaved differently than the surrounding clay-rich Martinsburg turbidites. Neither sediment type yielded detrital zircons. Electron backscatter X-ray diffraction (EBSD and calcite twinning results in a folded calcareous siltstone layer preserving a layer-normal SE-NW shortening strain and Lattice Preferred Orientation (LPO. Shortening axes for the five-phase calcite suite trends ~N40°W, consistent with tectonic transport associated with crystalline nappe emplacement of the Reading Prong within the Piedmont province.

Radial velocities of RR Lyrae stars

International Nuclear Information System (INIS)

Hawley, S.L.; Barnes, T.G. III

1985-01-01

283 spectra of 57 RR Lyrae stars have been obtained using the 2.1-m telescope at McDonald Observatory. Radial velocities were determined using a software cross-correlation technique. New mean radial velocities were determined for 46 of the stars. 11 references

The Reliability of Individualized Load-Velocity Profiles.

Science.gov (United States)

Banyard, Harry G; Nosaka, K; Vernon, Alex D; Haff, G Gregory

2017-11-15

This study examined the reliability of peak velocity (PV), mean propulsive velocity (MPV), and mean velocity (MV) in the development of load-velocity profiles (LVP) in the full depth free-weight back squat performed with maximal concentric effort. Eighteen resistance-trained men performed a baseline one-repetition maximum (1RM) back squat trial and three subsequent 1RM trials used for reliability analyses, with 48-hours interval between trials. 1RM trials comprised lifts from six relative loads including 20, 40, 60, 80, 90, and 100% 1RM. Individualized LVPs for PV, MPV, or MV were derived from loads that were highly reliable based on the following criteria: intra-class correlation coefficient (ICC) >0.70, coefficient of variation (CV) ≤10%, and Cohen's d effect size (ES) 0.05) between trials, movement velocities, or between linear regression versus second order polynomial fits. PV 20-100% , MPV 20-90% , and MV 20-90% are reliable and can be utilized to develop LVPs using linear regression. Conceptually, LVPs can be used to monitor changes in movement velocity and employed as a method for adjusting sessional training loads according to daily readiness.

Effects of shortening the dry period of dairy cows on milk production, energy balance, health, and fertility: A systemtic review

NARCIS (Netherlands)

Knegsel, van A.T.M.; Drift, van der S.G.A.; Cermáková, J.; Kemp, B.

2013-01-01

A dry period of 6–8 weeks for dairy cows is generally thought to maximise milk production in the next lactation. However, the value of such a long dry period is increasingly questioned. In particular, shortening the dry period shifts milk production from the critical period after calving to the

Global catalog of earthquake rupture velocities shows anticorrelation between stress drop and rupture velocity

Science.gov (United States)

Chounet, Agnès; Vallée, Martin; Causse, Mathieu; Courboulex, Françoise

2018-05-01

Application of the SCARDEC method provides the apparent source time functions together with seismic moment, depth, and focal mechanism, for most of the recent earthquakes with magnitude larger than 5.6-6. Using this large dataset, we have developed a method to systematically invert for the rupture direction and average rupture velocity Vr, when unilateral rupture propagation dominates. The approach is applied to all the shallow (z earthquakes of the catalog over the 1992-2015 time period. After a careful validation process, rupture properties for a catalog of 96 earthquakes are obtained. The subsequent analysis of this catalog provides several insights about the seismic rupture process. We first report that up-dip ruptures are more abundant than down-dip ruptures for shallow subduction interface earthquakes, which can be understood as a consequence of the material contrast between the slab and the overriding crust. Rupture velocities, which are searched without any a-priori up to the maximal P wave velocity (6000-8000 m/s), are found between 1200 m/s and 4500 m/s. This observation indicates that no earthquakes propagate over long distances with rupture velocity approaching the P wave velocity. Among the 23 ruptures faster than 3100 m/s, we observe both documented supershear ruptures (e.g. the 2001 Kunlun earthquake), and undocumented ruptures that very likely include a supershear phase. We also find that the correlation of Vr with the source duration scaled to the seismic moment (Ts) is very weak. This directly implies that both Ts and Vr are anticorrelated with the stress drop Δσ. This result has implications for the assessment of the peak ground acceleration (PGA) variability. As shown by Causse and Song (2015), an anticorrelation between Δσ and Vr significantly reduces the predicted PGA variability, and brings it closer to the observed variability.

Cerenkov detector for heavy-ion velocity measurements

International Nuclear Information System (INIS)

Olson, D.L.; Baumgartner, M.; Dufour, J.P.; Girard, J.G.; Greiner, D.E.; Lindstrom, P.J.; Symons, T.J.M.; Crawford, H.J.

1984-08-01

We have developed a highly sensitive velocity measuring detector using total-internal-reflection Cerenkov counters of a type mentioned by Jelly in 1958. If the velocity of the particle is above the threshold for total-internal-reflection these counters have a charge resolution of sigma = 0.18e for a 3mm thick glass radiator. For the velocity measurement we use a fused silica radiator so that the velocity of the particles are near the threshold for total-internal reflection. For momentum-analyzed projectile fragments of 1.6 GeV/nucleon 40 Ar, we have measured a mass resolution of sigma = 0.1u for isotope identification

Conduction velocity of antigravity muscle action potentials.

Science.gov (United States)

Christova, L; Kosarov, D; Christova, P

1992-01-01

The conduction velocity of the impulses along the muscle fibers is one of the parameters of the extraterritorial potentials of the motor units allowing for the evaluation of the functional state of the muscles. There are no data about the conduction velocities of antigravity muscleaction potentials. In this paper we offer a method for measuring conduction velocity of potentials of single MUs and the averaged potentials of the interference electromiogram (IEMG) lead-off by surface electrodes from mm. sternocleidomastoideus, trapezius, deltoideus (caput laterale) and vastus medialis. The measured mean values of the conduction velocity of antigravity muscles potentials can be used for testing the functional state of the muscles.

Double path-integral migration velocity analysis: a real data example

International Nuclear Information System (INIS)

Costa, Jessé C; Schleicher, Jörg

2011-01-01

Path-integral imaging forms an image with no knowledge of the velocity model by summing over the migrated images obtained for a set of migration velocity models. Double path-integral imaging migration extracts the stationary velocities, i.e. those velocities at which common-image gathers align horizontally, as a byproduct. An application of the technique to a real data set demonstrates that quantitative information about the time migration velocity model can be determined by double path-integral migration velocity analysis. Migrated images using interpolations with different regularizations of the extracted velocities prove the high quality of the resulting time-migration velocity information. The so-obtained velocity model can then be used as a starting model for subsequent velocity analysis tools like migration tomography or other tomographic methods

Migration velocity analysis using pre-stack wave fields

KAUST Repository

Alkhalifah, Tariq Ali; Wu, Zedong

2016-01-01

Using both image and data domains to perform velocity inversion can help us resolve the long and short wavelength components of the velocity model, usually in that order. This translates to integrating migration velocity analysis into full waveform

Phase velocity enhancement of linear explosive shock tubes

Science.gov (United States)

Loiseau, Jason; Serge, Matthew; Szirti, Daniel; Higgins, Andrew; Tanguay, Vincent

2011-06-01

Strong, high density shocks can be generated by sequentially detonating a hollow cylinder of explosives surrounding a thin-walled, pressurized tube. Implosion of the tube results in a pinch that travels at the detonation velocity of the explosive and acts like a piston to drive a shock into the gas ahead of it. In order to increase the maximum shock velocities that can be obtained, a phase velocity generator can be used to drag an oblique detonation wave along the gas tube at a velocity much higher than the base detonation velocity of the explosive. Since yielding and failure of the gas tube is the primary limitation of these devices, it is desirable to retain the dynamic confinement effects of a heavy-walled tamper without interfering with operation of the phase velocity generator. This was accomplished by cutting a slit into the tamper and introducing a phased detonation wave such that it asymmetrically wraps around the gas tube. This type of configuration has been previously experimentally verified to produce very strong shocks but the post-shock pressure and shock velocity limits have not been investigated. This study measured the shock trajectory for various fill pressures and phase velocities to ascertain the limiting effects of tube yield, detonation obliquity and pinch aspect ratio.

Critical Landau Velocity in Helium Nanodroplets

NARCIS (Netherlands)

Brauer, N.B.; Smolarek, S.; Loginov, E.; Mateo, D.; Hernando, A.; Pi, M.; Barranco, M.; Buma, W.J.; Drabbels, M.

2013-01-01

The best-known property of superfluid helium is the vanishing viscosity that objects experience while moving through the liquid with speeds below the so-called critical Landau velocity. This critical velocity is generally considered a macroscopic property as it is related to the collective

A new method for measurement of granular velocities

International Nuclear Information System (INIS)

Nyborg Andersen, B.

1984-01-01

A new, supplementary method to measure granular velocities is presented. The method utilizes the Doppler shift caused by the line of sight component of the solar rotation to cause a wavelength shift through spectral lines as function of heliocentric angle. By measuring the center-to-limb variation of the granular intensity fluctations at different wavelength positions in the lines, the velocities are found. To do this, assumptions regarding the geometrical structure of the velocity and intensity fields have to be made. Preliminary application of the method results in a steep velocity gradient suggesting zero velocity at a hight of 200 km above tau 500 = 1. Possible causes are discussed

Performance of a vector velocity estimator

DEFF Research Database (Denmark)

Munk, Peter; Jensen, Jørgen Arendt

1998-01-01

tracking can be found in the literature, but no method with a satisfactory performance has been found that can be used in a commercial implementation. A method for estimation of the velocity vector is presented. Here an oscillation transverse to the ultrasound beam is generated, so that a transverse motion...... in an autocorrelation approach that yields both the axial and the lateral velocity, and thus the velocity vector. The method has the advantage that a standard array transducer and a modified digital beamformer, like those used in modern ultrasound scanners, is sufficient to obtain the information needed. The signal...

Placental telomere shortening in stillbirth: a sign of premature senescence?

Science.gov (United States)

Ferrari, Francesca; Facchinetti, Fabio; Saade, George; Menon, Ramkumar

2016-01-01

The objective of this study is to investigate placental telomere shortening in unexplained stillbirths (SBs) as an indication of premature senescence. Placentas were collected from 42 unexplained SB (>22 weeks), 43 term and 15 preterm live births, at the Policlinico Hospital of Modena (Italy). DNA extracted from placentae was studied for telomere length by real time PCR. Standard curves were generated for telomere lengths from single copy gene amplifications using a reference DNA. The telomere length for each sample was derived based on the ratio of telomere length between the sample and single copy gene standard (T/S ratio). The mean ratio of placental telomere in term live births was 5.181 ± 3.841. A twofold decrease in telomere length was seen in SBs (over all 2.455 ± 1.239; p PTBs) (6.382 ± 5.525; p < 0.01), whereas SBs telomere length were similar to those of preterm premature rupture of membranes (pPROM) (3.296 ± 3.599; p = ns). Substantial reduction in telomere length in SBs is indicative of placental senescence. These data provide mechanistic insights that premature aging may lead to placental dysfunction as an initiator of fetal demise in unexplained SBs.

Burning velocity measurements of nitrogen-containing compounds.

Science.gov (United States)

Takizawa, Kenji; Takahashi, Akifumi; Tokuhashi, Kazuaki; Kondo, Shigeo; Sekiya, Akira

2008-06-30

Burning velocity measurements of nitrogen-containing compounds, i.e., ammonia (NH3), methylamine (CH3NH2), ethylamine (C2H5NH2), and propylamine (C3H7NH2), were carried out to assess the flammability of potential natural refrigerants. The spherical-vessel (SV) method was used to measure the burning velocity over a wide range of sample and air concentrations. In addition, flame propagation was directly observed by the schlieren photography method, which showed that the spherical flame model was applicable to flames with a burning velocity higher than approximately 5 cm s(-1). For CH3NH2, the nozzle burner method was also used to confirm the validity of the results obtained by closed vessel methods. We obtained maximum burning velocities (Su0,max) of 7.2, 24.7, 26.9, and 28.3 cm s(-1) for NH3, CH3NH2, C2H5NH2, and C3H7NH2, respectively. It was noted that the burning velocities of NH3 and CH3NH2 were as high as those of the typical hydrofluorocarbon refrigerants difluoromethane (HFC-32, Su0,max=6.7 cm s(-1)) and 1,1-difluoroethane (HFC-152a, Su0,max=23.6 cm s(-1)), respectively. The burning velocities were compared with those of the parent alkanes, and it was found that introducing an NH2 group into hydrocarbon molecules decreases their burning velocity.

Error detecting capabilities of the shortened Hamming codes adopted for error detection in IEEE Standard 802.3

Science.gov (United States)

Fujiwara, Toru; Kasami, Tadao; Lin, Shu

1989-09-01

The error-detecting capabilities of the shortened Hamming codes adopted for error detection in IEEE Standard 802.3 are investigated. These codes are also used for error detection in the data link layer of the Ethernet, a local area network. The weight distributions for various code lengths are calculated to obtain the probability of undetectable error and that of detectable error for a binary symmetric channel with bit-error rate between 0.00001 and 1/2.

Multiple joint muscle function with ageing: the force-velocity and power-velocity relationships in young and older men.

Science.gov (United States)

Allison, Sarah J; Brooke-Wavell, Katherine; Folland, Jonathan P

2013-05-01

Whilst extensive research has detailed the loss of muscle strength with ageing for isolated single joint actions, there has been little attention to power production during more functionally relevant multiple joint movements. The extent to which force or velocity are responsible for the loss in power with ageing is also equivocal. The aim of this study was to evaluate the contribution of force and velocity to the differences in power with age by comparing the force-velocity and power-velocity relationships in young and older men during a multiple joint leg press movement. Twenty-one older men (66 ± 3 years) and twenty-three young men (24 ± 2 years) completed a series of isometric (maximum and explosive) and dynamic contractions on a leg press dynamometer instrumented to record force and displacement. The force-velocity relationship was lower for the older men as reflected by their 19 % lower maximum isometric strength (p decrement in force was greater and therefore the major explanation for the attenuation of power during a functionally relevant multiple joint movement.

Variable gearing in a biologically inspired pneumatic actuator array

International Nuclear Information System (INIS)

Azizi, Emanuel; Roberts, Thomas J

2013-01-01

A fundamental feature of pennate muscles is that muscle fibers are oriented at an angle to the line of action and rotate as they shorten, becoming more oblique throughout a contraction. This change in fiber orientation (pennation angle) can amplify the shortening velocity of a fiber and increase output velocity of the muscle. The velocity advantage resulting from dynamic changes in pennation angle can be characterized as a gear ratio (muscle velocity/fiber velocity). A recent study has shown that a pennate muscle's gear ratio varies automatically depending on the load such that a muscle operates with a high gear during rapid contractions and low gear during forceful contractions. We examined whether this variable gearing behavior can be replicated in a pennate array of artificial muscles. We used McKibben type pneumatic actuators, which shorten in tension when filled with compressed gas. Similar to muscle fibers, the actuators expand radially during shortening, a feature thought to be a critical part of the variable gearing mechanism in pennate muscles. We arranged McKibben actuators in an array oriented to mimic a pennate muscle, and quantified the system's gear ratio during contraction against a range of loads. Video was used to measure the gear ratio during each contraction. We find that similar to pennate muscles, the gear ratio decreases significantly with increasing load and that variable gearing results from load-dependent variation in the amount of actuator rotation. These results support the idea that variable gearing in pennate muscles is mediated by difference is fiber rotation and the direction of muscle bulging. The behavior of our artificial muscle array also highlights the potential benefits of bio-inspired architectures in artificial muscle arrays, including the ability to vary force and speed automatically in response to variable loading conditions. (paper)

Variable gearing in a biologically inspired pneumatic actuator array.

Science.gov (United States)

Azizi, Emanuel; Roberts, Thomas J

2013-06-01

A fundamental feature of pennate muscles is that muscle fibers are oriented at an angle to the line of action and rotate as they shorten, becoming more oblique throughout a contraction. This change in fiber orientation (pennation angle) can amplify the shortening velocity of a fiber and increase output velocity of the muscle. The velocity advantage resulting from dynamic changes in pennation angle can be characterized as a gear ratio (muscle velocity/fiber velocity). A recent study has shown that a pennate muscle's gear ratio varies automatically depending on the load such that a muscle operates with a high gear during rapid contractions and low gear during forceful contractions. We examined whether this variable gearing behavior can be replicated in a pennate array of artificial muscles. We used McKibben type pneumatic actuators, which shorten in tension when filled with compressed gas. Similar to muscle fibers, the actuators expand radially during shortening, a feature thought to be a critical part of the variable gearing mechanism in pennate muscles. We arranged McKibben actuators in an array oriented to mimic a pennate muscle, and quantified the system's gear ratio during contraction against a range of loads. Video was used to measure the gear ratio during each contraction. We find that similar to pennate muscles, the gear ratio decreases significantly with increasing load and that variable gearing results from load-dependent variation in the amount of actuator rotation. These results support the idea that variable gearing in pennate muscles is mediated by difference is fiber rotation and the direction of muscle bulging. The behavior of our artificial muscle array also highlights the potential benefits of bio-inspired architectures in artificial muscle arrays, including the ability to vary force and speed automatically in response to variable loading conditions.

VARIABLE GEARING IN A BIOLOGICALLY-INSPIRED PNEUMATIC ACTUATOR ARRAY

Science.gov (United States)

Azizi, Emanuel; Roberts, Thomas J.

2013-01-01

A fundamental feature of pennate muscles is that muscle fibers are oriented at an angle to the line of action and rotate as they shorten, becoming more oblique throughout a contraction. This change in fiber orientation (pennation angle) can amplify the shortening velocity of a fiber and increase output velocity of the muscle. The velocity advantage resulting from dynamic changes in pennation angle can be characterized as a gear ratio (muscle velocity/fiber velocity). A recent study has shown that a pennate muscle’s gear ratio varies automatically depending on the load such that a muscle operates with a high gear during rapid contractions and low gear during forceful contractions. We examined whether this variable gearing behavior can be replicated in a pennate array of artificial muscles. We used McKibben type pneumatic actuators, which shorten in tension when filled with compressed gas. Similar to muscle fibers, the actuators expand radially during shortening, a feature thought to be a critical part of the variable gearing mechanism in pennate muscles. We arranged McKibben actuators in an array oriented to mimic a pennate muscle, and quantified the system’s gear ratio during contraction against a range of loads. Video was used to measure the gear ratio during each contraction. We find that similar to pennate muscles, the gear ratio decreases significantly with increasing load and that variable gearing results from load-dependent variation in the amount of actuator rotation. These results support the idea that variable gearing in pennate muscles is mediated by difference is fiber rotation and the direction of muscle bulging. The behavior of our artificial muscle array also highlights the potential benefits of bio-inspired architectures in artificial muscle arrays, including the ability to vary force and speed automatically in response to variable loading conditions. PMID:23462288

3D T2-weighted imaging to shorten multiparametric prostate MRI protocols.

Science.gov (United States)

Polanec, Stephan H; Lazar, Mathias; Wengert, Georg J; Bickel, Hubert; Spick, Claudio; Susani, Martin; Shariat, Shahrokh; Clauser, Paola; Baltzer, Pascal A T

2018-04-01

To determine whether 3D acquisitions provide equivalent image quality, lesion delineation quality and PI-RADS v2 performance compared to 2D acquisitions in T2-weighted imaging of the prostate at 3 T. This IRB-approved, prospective study included 150 consecutive patients (mean age 63.7 years, 35-84 years; mean PSA 7.2 ng/ml, 0.4-31.1 ng/ml). Two uroradiologists (R1, R2) independently rated image quality and lesion delineation quality using a five-point ordinal scale and assigned a PI-RADS score for 2D and 3D T2-weighted image data sets. Data were compared using visual grading characteristics (VGC) and receiver operating characteristics (ROC)/area under the curve (AUC) analysis. Image quality was similarly good to excellent for 2D T2w (mean score R1, 4.3 ± 0.81; R2, 4.7 ± 0.83) and 3D T2w (mean score R1, 4.3 ± 0.82; R2, 4.7 ± 0.69), p = 0.269. Lesion delineation was rated good to excellent for 2D (mean score R1, 4.16 ± 0.81; R2, 4.19 ± 0.92) and 3D T2w (R1, 4.19 ± 0.94; R2, 4.27 ± 0.94) without significant differences (p = 0.785). ROC analysis showed an equivalent performance for 2D (AUC 0.580-0.623) and 3D (AUC 0.576-0.629) T2w (p > 0.05, respectively). Three-dimensional acquisitions demonstrated equivalent image and lesion delineation quality, and PI-RADS v2 performance, compared to 2D in T2-weighted imaging of the prostate. Three-dimensional T2-weighted imaging could be used to considerably shorten prostate MRI protocols in clinical practice. • 3D shows equivalent image quality and lesion delineation compared to 2D T2w. • 3D T2w and 2D T2w image acquisition demonstrated comparable diagnostic performance. • Using a single 3D T2w acquisition may shorten the protocol by 40%. • Combined with short DCE, multiparametric protocols of 10 min are feasible.

Comparison of high group velocity accelerating structures

International Nuclear Information System (INIS)

Farkas, Z.D.; Wilson, P.B.

1987-02-01

It is well known that waveguides with no perturbations have phase velocities greater than the velocity of light c. If the waveguide dimensions are chosen so that the phase velocity is only moderately greater than c, only small perturbations are required to reduce the phase velocity to be synchronous with a high energy particle bunch. Such a lightly loaded accelerator structure will have smaller longitudinal and transverse wake potentials and hence will lead to lower emittance growth in an accelerated beam. Since these structures are lightly loaded, their group velocities are only slightly less than c and not in the order of 0.01c, as is the case for the standard disk-loaded structures. To ascertain that the peak and average power requirements for these structures are not prohibitive, we examine the elastance and the Q for several traveling wave structures: phase slip structures, bellows-like structures, and lightly loaded disk-loaded structures

A glance at velocity structure of Izmir

Energy Technology Data Exchange (ETDEWEB)

Özer, Çağlar, E-mail: caglar.ozer@deu.edu.tr [Dokuz Eylul University, Faculty of Engineering, Geophysical Engineering Department, Izmir (Turkey); Dokuz Eylul University, The Graduate School of Natural and Applied Sciences, Department of Geophysical Engineering, Izmir (Turkey); Polat, Orhan, E-mail: orhan.polat@deu.edu.tr [Dokuz Eylul University, Faculty of Engineering, Geophysical Engineering Department, Izmir (Turkey)

2016-04-18

In this study; we investigated velocity structure of Izmir and surroundings. We used local earthquake data which was recorded by different type of instruments and obtained high resolution 3D sections. We selected more than 400 earthquakes which were occurred between 2010 and 2013. Examined tomographic sections especially in Izmir along coastal areas (Mavisehir-Inciraltı); revealed the low speed zone. Along this low-speed zone; it is consistent with the results obtained from the stratigraphic section and surface geology. While; low velocity zones are associated with faults and water content; high velocity is related to magmatic rocks or compact rocks. Along Karsıyaka, Seferihisar, Orhanlı, Izmir fault zones; low P velocity was observed. When examined higher elevations of the topography; which are composed of soured magmatic material is dominated by high P velocity. In all horizontal sections; resolution decreasing with increasing depth. The reason for this; the reduction of earthquakes causes ray tracing problems.

Coding of Velocity Storage in the Vestibular Nuclei

Directory of Open Access Journals (Sweden)

Sergei B. Yakushin

2017-08-01

Full Text Available Semicircular canal afferents sense angular acceleration and output angular velocity with a short time constant of ≈4.5 s. This output is prolonged by a central integrative network, velocity storage that lengthens the time constants of eye velocity. This mechanism utilizes canal, otolith, and visual (optokinetic information to align the axis of eye velocity toward the spatial vertical when head orientation is off-vertical axis. Previous studies indicated that vestibular-only (VO and vestibular-pause-saccade (VPS neurons located in the medial and superior vestibular nucleus could code all aspects of velocity storage. A recently developed technique enabled prolonged recording while animals were rotated and received optokinetic stimulation about a spatial vertical axis while upright, side-down, prone, and supine. Firing rates of 33 VO and 8 VPS neurons were studied in alert cynomolgus monkeys. Majority VO neurons were closely correlated with the horizontal component of velocity storage in head coordinates, regardless of head orientation in space. Approximately, half of all tested neurons (46% code horizontal component of velocity in head coordinates, while the other half (54% changed their firing rates as the head was oriented relative to the spatial vertical, coding the horizontal component of eye velocity in spatial coordinates. Some VO neurons only coded the cross-coupled pitch or roll components that move the axis of eye rotation toward the spatial vertical. Sixty-five percent of these VO and VPS neurons were more sensitive to rotation in one direction (predominantly contralateral, providing directional orientation for the subset of VO neurons on either side of the brainstem. This indicates that the three-dimensional velocity storage integrator is composed of directional subsets of neurons that are likely to be the bases for the spatial characteristics of velocity storage. Most VPS neurons ceased firing during drowsiness, but the firing

Superluminal Velocities in the Synchronized Space-Time

Directory of Open Access Journals (Sweden)

Medvedev S. Yu.

2014-07-01

Full Text Available Within the framework of the non-gravitational generalization of the special relativity, a problem of possible superluminal motion of particles and signals is considered. It has been proven that for the particles with non-zero mass the existence of anisotropic light barrier with the shape dependent on the reference frame velocity results from the Tangherlini transformations. The maximal possible excess of neutrino velocity over the absolute velocity of light related to the Earth (using th e clock with instantaneous synchronization has been estimated. The illusoriness of t he acausality problem has been illustrated and conclusion is made on the lack of the upper limit of velocities of signals of informational nature.

Imaging chemical reactions - 3D velocity mapping

Science.gov (United States)

Chichinin, A. I.; Gericke, K.-H.; Kauczok, S.; Maul, C.

Visualising a collision between an atom or a molecule or a photodissociation (half-collision) of a molecule on a single particle and single quantum level is like watching the collision of billiard balls on a pool table: Molecular beams or monoenergetic photodissociation products provide the colliding reactants at controlled velocity before the reaction products velocity is imaged directly with an elaborate camera system, where one should keep in mind that velocity is, in general, a three-dimensional (3D) vectorial property which combines scattering angles and speed. If the processes under study have no cylindrical symmetry, then only this 3D product velocity vector contains the full information of the elementary process under study.

The Spiritual Well-Being Scale: Psychometric Evaluation of the Shortened Version in Czech Adolescents.

Science.gov (United States)

Malinakova, Klara; Kopcakova, Jaroslava; Kolarcik, Peter; Geckova, Andrea Madarasova; Solcova, Iva Polackova; Husek, Vit; Kracmarova, Lucie Kluzova; Dubovska, Eva; Kalman, Michal; Puzova, Zuzana; van Dijk, Jitse P; Tavel, Peter

2017-04-01

The aim of this study was to psychometrically evaluate the shortened version of the Spiritual Well-Being Scale (SWBS) in Czech adolescents. A nationally representative sample of 4217 adolescents participated in the 2014 Health Behaviour in School-aged Children survey. The internal consistency of the SWBS was assessed using Cronbach's alpha (α) and Mean Inter-Item Correlation (MIIC) values. The factor structure was evaluated using principal component analyses. After adjustment, our new seven-item version of the scale supports a two-factorial model of the SWBS with satisfactory internal consistency (α = 0.814, MIIC = 0.379). This version of the SWBS is suitable for measuring spiritual well-being in a secularising environment.

Is the shortened dental arch still a satisfactory option?

Science.gov (United States)

Manola, M; Hussain, F; Millar, B J

2017-07-21

Aims Dental practitioners may hold the view that missing posterior teeth should be replaced to ensure a healthy masticatory system and satisfactory oral function. However, the shortened dental arch (SDA) concept is still in use, but after 35 years is it acceptable? This review searches the literature for the evidence and opinions regarding the suitability of the SDA as a current treatment modality.Methods Medline and PubMed databases were searched for relevant terms, all the abstracts were assessed and articles selected according to the pre-set exclusion and inclusion criteria.Results The search yielded 1,895 articles and after the assessment of the abstracts and application of the exclusion and inclusion criteria, 44 articles were selected for this review. These included 11 cohort studies, two longitudinal studies, two animal studies, three cross sectional studies, eight clinical studies and 18 case control studies. There appears to be a trend over the past three decades for more papers to be opposed to the SDA concept.Conclusion Evidence that the SDA causes pathology is lacking. Clinicians, healthcare authorities and patients have shown favourable attitudes towards the SDA and this continues, although there is an increase in studies opposing the concept and some are dissatisfied with this option. The concept remains viable particularly for the medically compromised patient or where restorations are considered unsuitable but further more specific studies are warranted.

Estimation of blood velocities using ultrasound

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt

imaging, and, finally, some of the more recent experimental techniques. The authors shows that the Doppler shift, usually considered the way velocity is detected, actually, plays a minor role in pulsed systems. Rather, it is the shift of position of signals between pulses that is used in velocity...

Temperature and center-limb variations of transition region velocities

International Nuclear Information System (INIS)

Athay, R.G.; Dere, K.P.

1989-01-01

HRTS data from the Spacelab 2 mission are used to derive the center-limb and temperature variations of the mean velocity and the velocity variance in the solar chromosphere and transition zone. The mean velocity is found to vary much more rapidly from center to limb and with temperature than does the velocity variance. Also, the mean velocity shows a characteristic signature at some magnetic neutral lines in accordance with the findings of Klimchuk (1987) from Solar Maximum Mission (SMM) data. The velocity variance does not show a characteristic signature at the neutral lines but shows an inverse correlation with intensity. The latter is interpreted as reduced velocity variance in strong field regions. The results are discussed in terms of downflow along lines of force in magnetic arcades. 23 refs

Rapid Geodetic Shortening Across the Eastern Cordillera of NW Argentina Observed by the Puna-Andes GPS Array

Science.gov (United States)

McFarland, Phillip K.; Bennett, Richard A.; Alvarado, Patricia; DeCelles, Peter G.

2017-10-01

We present crustal velocities for 29 continuously recording GPS stations from the southern central Andes across the Puna, Eastern Cordillera, and Santa Barbara system for the period between the 27 February 2010 Maule and 1 April 2014 Iquique earthquakes in a South American frame. The velocity field exhibits a systematic decrease in magnitude from 35 mm/yr near the trench to convergence accommodated at the subduction interface. Velocity residuals calculated for each model demonstrate that locking on the NZ-SA interface is insufficient to reproduce the observed velocities. We model deformation associated with a back-arc décollement using an edge dislocation, estimating model parameters from the velocity residuals for each forward model of the subduction interface ensemble using a Bayesian approach. We realize our best fit to the thrust-perpendicular velocity field with 70 ± 5% of NZ-SA convergence accommodated at the subduction interface and a slip rate of 9.1 ± 0.9 mm/yr on the fold-thrust belt décollement. We also estimate a locking depth of 14 ± 9 km, which places the downdip extent of the locked zone 135 ± 20 km from the thrust front. The thrust-parallel component of velocity is fit by a constant shear strain rate of -19 × 10-9 yr-1, equivalent to clockwise rigid block rotation of the back arc at a rate of 1.1°/Myr.

The Velocity Distribution of Isolated Radio Pulsars

Science.gov (United States)

Arzoumanian, Z.; Chernoff, D. F.; Cordes, J. M.; White, Nicholas E. (Technical Monitor)

2002-01-01

We infer the velocity distribution of radio pulsars based on large-scale 0.4 GHz pulsar surveys. We do so by modelling evolution of the locations, velocities, spins, and radio luminosities of pulsars; calculating pulsed flux according to a beaming model and random orientation angles of spin and beam; applying selection effects of pulsar surveys; and comparing model distributions of measurable pulsar properties with survey data using a likelihood function. The surveys analyzed have well-defined characteristics and cover approx. 95% of the sky. We maximize the likelihood in a 6-dimensional space of observables P, dot-P, DM, absolute value of b, mu, F (period, period derivative, dispersion measure, Galactic latitude, proper motion, and flux density). The models we test are described by 12 parameters that characterize a population's birth rate, luminosity, shutoff of radio emission, birth locations, and birth velocities. We infer that the radio beam luminosity (i) is comparable to the energy flux of relativistic particles in models for spin-driven magnetospheres, signifying that radio emission losses reach nearly 100% for the oldest pulsars; and (ii) scales approximately as E(exp 1/2) which, in magnetosphere models, is proportional to the voltage drop available for acceleration of particles. We find that a two-component velocity distribution with characteristic velocities of 90 km/ s and 500 km/ s is greatly preferred to any one-component distribution; this preference is largely immune to variations in other population parameters, such as the luminosity or distance scale, or the assumed spin-down law. We explore some consequences of the preferred birth velocity distribution: (1) roughly 50% of pulsars in the solar neighborhood will escape the Galaxy, while approx. 15% have velocities greater than 1000 km/ s (2) observational bias against high velocity pulsars is relatively unimportant for surveys that reach high Galactic absolute value of z distances, but is severe for

Mechanisms of breast cancer risk in shift workers: association of telomere shortening with the duration and intensity of night work.

Science.gov (United States)

Samulin Erdem, Johanna; Notø, Heidi Ødegaard; Skare, Øivind; Lie, Jenny-Anne S; Petersen-Øverleir, Marte; Reszka, Edyta; Pepłońska, Beata; Zienolddiny, Shanbeh

2017-08-01

Occupational factors such as shiftwork and especially night work that involves disruption of the circadian rhythm may contribute to increased breast cancer risk. Circadian disruption may also affect telomere length (TL). While short TL generally is associated with increased cancer risk, its association with breast cancer risk is inconclusive. We suggest that working schedules might be an important factor in assessment of effects of TL on breast cancer risk. Moreover, telomere shortening might be a potential mechanism for night work-related breast cancer. In this study, effects of shift work on TL and its association with breast cancer risk were investigated in a nested breast cancer case-control study of Norwegian nurses. TL was assessed by qPCR in DNA from 563 breast cancer patients and 619 controls. Here, we demonstrate that TL is affected by intensive night work schedules, as work with six consecutive night for a period of more than 5 years was associated with decreased telomere lengths (-3.18, 95% CI: -6.46 to -0.58, P = 0.016). Furthermore, telomere shortening is associated with increased breast cancer risk in workers with long periods of consecutive night shifts. Thus, nurses with longer telomere lengths had a lower risk for breast cancer if they had worked more than four (OR: 0.37, 95% CI: 0.16-0.79, P = 0.014) or five (OR: 0.31, 95% CI: 0.10-0.83, P = 0.029) consecutive night shifts for a period of 5 years or more. These data suggest that telomere shortening is associated with the duration and intensity of night work and may be a contributing factor for breast cancer risk among female shift workers. © 2017 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

Neutron stars velocities and magnetic fields

Science.gov (United States)

Paret, Daryel Manreza; Martinez, A. Perez; Ayala, Alejandro.; Piccinelli, G.; Sanchez, A.

2018-01-01

We study a model that explain neutron stars velocities due to the anisotropic emission of neutrinos. Strong magnetic fields present in neutron stars are the source of the anisotropy in the system. To compute the velocity of the neutron star we model its core as composed by strange quark matter and analice the properties of a magnetized quark gas at finite temperature and density. Specifically we have obtained the electron polarization and the specific heat of magnetized fermions as a functions of the temperature, chemical potential and magnetic field which allow us to study the velocity of the neutron star as a function of these parameters.

Examples of in-vivo blood vector velocity estimation

DEFF Research Database (Denmark)

Udesen, Jesper; Nielsen, Michael Bachmann; Nielsen, Kristian R.

2007-01-01

In this paper examples of in-vivo blood vector velocity images of the carotid artery are presented. The transverse oscillation (TO) method for blood vector velocity estimation has been used to estimate the vector velocities and the method is first evaluated in a circulating flowrig where...

Evaluation of force-velocity and power-velocity relationship of arm muscles.

Science.gov (United States)

Sreckovic, Sreten; Cuk, Ivan; Djuric, Sasa; Nedeljkovic, Aleksandar; Mirkov, Dragan; Jaric, Slobodan

2015-08-01

A number of recent studies have revealed an approximately linear force-velocity (F-V) and, consequently, a parabolic power-velocity (P-V) relationship of multi-joint tasks. However, the measurement characteristics of their parameters have been neglected, particularly those regarding arm muscles, which could be a problem for using the linear F-V model in both research and routine testing. Therefore, the aims of the present study were to evaluate the strength, shape, reliability, and concurrent validity of the F-V relationship of arm muscles. Twelve healthy participants performed maximum bench press throws against loads ranging from 20 to 70 % of their maximum strength, and linear regression model was applied on the obtained range of F and V data. One-repetition maximum bench press and medicine ball throw tests were also conducted. The observed individual F-V relationships were exceptionally strong (r = 0.96-0.99; all P stronger relationships. The reliability of parameters obtained from the linear F-V regressions proved to be mainly high (ICC > 0.80), while their concurrent validity regarding directly measured F, P, and V ranged from high (for maximum F) to medium-to-low (for maximum P and V). The findings add to the evidence that the linear F-V and, consequently, parabolic P-V models could be used to study the mechanical properties of muscular systems, as well as to design a relatively simple, reliable, and ecologically valid routine test of the muscle ability of force, power, and velocity production.

The solidification velocity of nickel and titanium alloys

Science.gov (United States)

Altgilbers, Alex Sho

2002-09-01

The solidification velocity of several Ni-Ti, Ni-Sn, Ni-Si, Ti-Al and Ti-Ni alloys were measured as a function of undercooling. From these results, a model for alloy solidification was developed that can be used to predict the solidification velocity as a function of undercooling more accurately. During this investigation a phenomenon was observed in the solidification velocity that is a direct result of the addition of the various alloying elements to nickel and titanium. The additions of the alloying elements resulted in an additional solidification velocity plateau at intermediate undercoolings. Past work has shown a solidification velocity plateau at high undercoolings can be attributed to residual oxygen. It is shown that a logistic growth model is a more accurate model for predicting the solidification of alloys. Additionally, a numerical model is developed from simple description of the effect of solute on the solidification velocity, which utilizes a Boltzmann logistic function to predict the plateaus that occur at intermediate undercoolings.

A new car-following model considering velocity anticipation

International Nuclear Information System (INIS)

Jun-Fang, Tian; Bin, Jia; Xin-Gang, Li; Zi-You, Gao

2010-01-01

The full velocity difference model proposed by Jiang et al. [2001 Phys. Rev. E 64 017101] has been improved by introducing velocity anticipation. Velocity anticipation means the follower estimates the future velocity of the leader. The stability condition of the new model is obtained by using the linear stability theory. Theoretical results show that the stability region increases when we increase the anticipation time interval. The mKdV equation is derived to describe the kink–antikink soliton wave and obtain the coexisting stability line. The delay time of car motion and kinematic wave speed at jam density are obtained in this model. Numerical simulations exhibit that when we increase the anticipation time interval enough, the new model could avoid accidents under urgent braking cases. Also, the traffic jam could be suppressed by considering the anticipation velocity. All results demonstrate that this model is an improvement on the full velocity difference model. (general)

On the origin of high-velocity runaway stars

Science.gov (United States)

Gvaramadze, Vasilii V.; Gualandris, Alessia; Portegies Zwart, Simon

2009-06-01

We explore the hypothesis that some high-velocity runaway stars attain their peculiar velocities in the course of exchange encounters between hard massive binaries and a very massive star (either an ordinary 50-100Msolar star or a more massive one, formed through runaway mergers of ordinary stars in the core of a young massive star cluster). In this process, one of the binary components becomes gravitationally bound to the very massive star, while the second one is ejected, sometimes with a high speed. We performed three-body scattering experiments and found that early B-type stars (the progenitors of the majority of neutron stars) can be ejected with velocities of >~200-400kms-1 (typical of pulsars), while 3-4Msolar stars can attain velocities of >~300-400kms-1 (typical of the bound population of halo late B-type stars). We also found that the ejected stars can occasionally attain velocities exceeding the Milky Ways's escape velocity.

A model of optimal voluntary muscular control.

Science.gov (United States)

FitzHugh, R

1977-07-19

In the absence of detailed knowledge of how the CNS controls a muscle through its motor fibers, a reasonable hypothesis is that of optimal control. This hypothesis is studied using a simplified mathematical model of a single muscle, based on A.V. Hill's equations, with series elastic element omitted, and with the motor signal represented by a single input variable. Two cost functions were used. The first was total energy expended by the muscle (work plus heat). If the load is a constant force, with no inertia, Hill's optimal velocity of shortening results. If the load includes a mass, analysis by optimal control theory shows that the motor signal to the muscle consists of three phases: (1) maximal stimulation to accelerate the mass to the optimal velocity as quickly as possible, (2) an intermediate level of stimulation to hold the velocity at its optimal value, once reached, and (3) zero stimulation, to permit the mass to slow down, as quickly as possible, to zero velocity at the specified distance shortened. If the latter distance is too small, or the mass too large, the optimal velocity is not reached, and phase (2) is absent. For lengthening, there is no optimal velocity; there are only two phases, zero stimulation followed by maximal stimulation. The second cost function was total time. The optimal control for shortening consists of only phases (1) and (3) above, and is identical to the minimal energy control whenever phase (2) is absent from the latter. Generalization of this model to include viscous loads and a series elastic element are discussed.

Effect of splitting a mixed-model line on shortening the line length under open- and closed-boundary working area settings

Science.gov (United States)

Zhang, Donghao; Matsuura, Haruki; Asada, Akiko

2017-04-01

Some automobile factories have segmented mixed-model production lines into shorter sub-lines according to part group, such as engine, trim, and powertrain. The effects of splitting a line into sub-lines have been reported from the standpoints of worker motivation, productivity improvement, and autonomy based on risk spreading. There has been no mention of the possibility of shortening the line length by altering the product sequence using sub-lines. The purpose of the present paper is to determine the conditions under which sub-lines reduce the line length and the degree to which the line length may be shortened. The line lengths for a non-split line and a line that has been split into sub-lines are compared using three methods for determining the working area, the standard closed boundary, the optimized open boundary, and real-life constant-length stations. The results are discussed by analyzing the upper and lower bounds of the line length. Based on these results, a procedure for deciding whether or not to split a production line is proposed.

Study on velocity field in a wire wrapped fuel pin bundle of sodium cooled reactor. Detailed velocity distribution in a subchannel

International Nuclear Information System (INIS)

Sato, Hiroyuki; Kobayashi, Jun; Miyakoshi, Hiroyuki; Kamide, Hideki

2009-01-01

A sodium cooled fast reactor is designed to attain a high burn-up core in a feasibility study on commercialized fast reactor cycle systems. In high burn-up fuel subassemblies, deformation of fuel pin due to the swelling and thermal bowing may decrease local flow velocity via change of flow area in the subassembly and influence the heat removal capability. Therefore, it is of importance to obtain the flow velocity distribution in a wire wrapped pin bundle. A 2.5 times enlarged 7-pin bundle water model was applied to investigate the detailed velocity distribution in an inner subchannel surrounded by 3 pins with wrapping wire. The test section consisted of a hexagonal acrylic duct tube and fluorinated resin pins which had nearly the same refractive index with that of water and a high light transmission rate. The velocity distribution in an inner subchannel with the wrapping wire was measured by PIV (Particle Image Velocimetry) through the front and lateral sides of the duct tube. In the vertical velocity distribution in a narrow space between the pins, the wrapping wire decreased the velocity downstream of the wire and asymmetric flow distribution was formed between the pin and wire. In the horizontal velocity distribution, swirl flow around the wrapping wire was obviously observed. The measured velocity data are useful for code validation of pin bundle thermalhydraulics. (author)

Time-resolved x-ray diffraction from frog skeletal muscle during shortening against an inertial load and a quick release

International Nuclear Information System (INIS)

Amemiya, Yoshiyuki; Hashizume, Hiroo; Tameyasu, Tsukasa; Tanaka, Hidehiro; Sugi, Haruo.

1980-01-01

A group of Japanese researchers conducted, for the first time in this field, experiments on time-resolved x-ray diffraction of frog (bullfrog, Rana catesbeiana) skeletal muscle in conditions where both the force and the muscle length change with time. During an isotonic twitch under a load of about 0.3 P 0 , the intensity ratio started falling on stimulation and reached a minimum value of 0.5 - 0.6 at the early shortening phase, which was maintained until the beginning of relaxation. Except that the minimum value was not retained until the start of relaxation, the same was observed during a twitch against an inertial load whereby the peak force exerted by the muscle was about 0.4 P 0 . The results may be taken to indicate that the change in the intensity ratio reflects not the time course of shortening but that of force generation. When a quick release (3 - 4% of muscle length) was applied during the rising phase of an isometric twitch, the intensity ratio showed no distinct change. Judging from tentative calculation results, however, the foregoing result is subject to further experiments with a much improved time resolution of the measurements. (Kitajima, A.)

Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis.

Directory of Open Access Journals (Sweden)

George L Drusano

Full Text Available Tuberculosis remains a worldwide problem, particularly with the advent of multi-drug resistance. Shortening therapy duration for Mycobacterium tuberculosis is a major goal, requiring generation of optimal kill rate and resistance-suppression. Combination therapy is required to attain the goal of shorter therapy.Our objective was to identify a method for identifying optimal combination chemotherapy. We developed a mathematical model for attaining this end. This is accomplished by identifying drug effect interaction (synergy, additivity, antagonism for susceptible organisms and subpopulations resistant to each drug in the combination.We studied the combination of linezolid plus rifampin in our hollow fiber infection model. We generated a fully parametric drug effect interaction mathematical model. The results were subjected to Monte Carlo simulation to extend the findings to a population of patients by accounting for between-patient variability in drug pharmacokinetics.All monotherapy allowed emergence of resistance over the first two weeks of the experiment. In combination, the interaction was additive for each population (susceptible and resistant. For a 600 mg/600 mg daily regimen of linezolid plus rifampin, we demonstrated that >50% of simulated subjects had eradicated the susceptible population by day 27 with the remaining organisms resistant to one or the other drug. Only 4% of patients had complete organism eradication by experiment end.These data strongly suggest that in order to achieve the goal of shortening therapy, the original regimen may need to be changed at one month to a regimen of two completely new agents with resistance mechanisms independent of the initial regimen. This hypothesis which arose from the analysis is immediately testable in a clinical trial.

Reliability of force-velocity relationships during deadlift high pull.

Science.gov (United States)

Lu, Wei; Boyas, Sébastien; Jubeau, Marc; Rahmani, Abderrahmane

2017-11-13

This study aimed to evaluate the within- and between-session reliability of force, velocity and power performances and to assess the force-velocity relationship during the deadlift high pull (DHP). Nine participants performed two identical sessions of DHP with loads ranging from 30 to 70% of body mass. The force was measured by a force plate under the participants' feet. The velocity of the 'body + lifted mass' system was calculated by integrating the acceleration and the power was calculated as the product of force and velocity. The force-velocity relationships were obtained from linear regression of both mean and peak values of force and velocity. The within- and between-session reliability was evaluated by using coefficients of variation (CV) and intraclass correlation coefficients (ICC). Results showed that DHP force-velocity relationships were significantly linear (R² > 0.90, p  0.94), mean and peak velocities showed a good agreement (CV reliable and can therefore be utilised as a tool to characterise individuals' muscular profiles.

High-velocity runaway stars from three-body encounters

Science.gov (United States)

Gvaramadze, V. V.; Gualandris, A.; Portegies Zwart, S.

2010-01-01

We performed numerical simulations of dynamical encounters between hard, massive binaries and a very massive star (VMS; formed through runaway mergers of ordinary stars in the dense core of a young massive star cluster) to explore the hypothesis that this dynamical process could be responsible for the origin of high-velocity (≥ 200 - 400 km s-1) early or late B-type stars. We estimated the typical velocities produced in encounters between very tight massive binaries and VMSs (of mass of ≥ 200 M⊙) and found that about 3 - 4% of all encounters produce velocities ≥ 400 km s-1, while in about 2% of encounters the escapers attain velocities exceeding the Milky Ways's escape velocity. We therefore argue that the origin of high-velocity (≥ 200 - 400 km s-1) runaway stars and at least some so-called hypervelocity stars could be associated with dynamical encounters between the tightest massive binaries and VMSs formed in the cores of star clusters. We also simulated dynamical encounters between tight massive binaries and single ordinary 50 - 100 M⊙ stars. We found that from 1 to ≃ 4% of these encounters can produce runaway stars with velocities of ≥ 300 - 400 km s-1 (typical of the bound population of high-velocity halo B-type stars) and occasionally (in less than 1% of encounters) produce hypervelocity (≥ 700 km s-1) late B-type escapers.

Determination of viscosity through terminal velocity: use of the drag force with a quadratic term in velocity

DEFF Research Database (Denmark)

Vertchenko, Lev; Vertchenko, Larissa

2017-01-01

A correction to the term with quadratic dependency of the velocity in the Oseen´s drag force by a dimensionless factor is proposed in order to determine the viscosity of glycerin through the measurement of the terminal velocity of spheres falling inside the fluid. This factor incorporates the eff...

Paintball velocity as a function of distance traveled

Directory of Open Access Journals (Sweden)

Pat Chiarawongse

2008-06-01

Full Text Available The relationship between the distance a paintball travels through air and its velocity is investigated by firing a paintball into a ballistic pendulum from a range of distances. The motion of the pendulum was filmed and analyzed by using video analysis software. The velocity of the paintball on impact was calculated from the maximum horizontal displacement of the pendulum. It is shown that the velocity of a paintball decreases exponentially with distance traveled, as expected. The average muzzle velocity of the paint balls is found with an estimate of the drag coefficient.

Paintball velocity as a function of distance traveled

Directory of Open Access Journals (Sweden)

Pat Chiarawongse

2008-06-01

Full Text Available The relationship between the distance a paintball travels through air and its velocity is investigated by firing a paintball into a ballistic pendulum from a range of distances. The motion of the pendulum was filmed and analyzed by using video analysis software. The velocity of the paintball on impact was calculated from the maximum horizontal displacement of the pendulum. It is shown that the velocity of a paintball decreases exponentially with distance traveled, as expected. The average muzzle velocity of the paint balls is found with an estimate of the drag coefficient

Streaming Velocities and the Baryon Acoustic Oscillation Scale.

Science.gov (United States)

Blazek, Jonathan A; McEwen, Joseph E; Hirata, Christopher M

2016-03-25

At the epoch of decoupling, cosmic baryons had supersonic velocities relative to the dark matter that were coherent on large scales. These velocities subsequently slow the growth of small-scale structure and, via feedback processes, can influence the formation of larger galaxies. We examine the effect of streaming velocities on the galaxy correlation function, including all leading-order contributions for the first time. We find that the impact on the baryon acoustic oscillation (BAO) peak is dramatically enhanced (by a factor of ∼5) over the results of previous investigations, with the primary new effect due to advection: if a galaxy retains memory of the primordial streaming velocity, it does so at its Lagrangian, rather than Eulerian, position. Since correlations in the streaming velocity change rapidly at the BAO scale, this advection term can cause a significant shift in the observed BAO position. If streaming velocities impact tracer density at the 1% level, compared to the linear bias, the recovered BAO scale is shifted by approximately 0.5%. This new effect, which is required to preserve Galilean invariance, greatly increases the importance of including streaming velocities in the analysis of upcoming BAO measurements and opens a new window to the astrophysics of galaxy formation.

A new estimator for vector velocity estimation [medical ultrasonics

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt

2001-01-01

A new estimator for determining the two-dimensional velocity vector using a pulsed ultrasound field is derived. The estimator uses a transversely modulated ultrasound field for probing the moving medium under investigation. A modified autocorrelation approach is used in the velocity estimation...... be introduced, and the velocity estimation is done at a fixed depth in tissue to reduce the influence of a spatial velocity spread. Examples for different velocity vectors and field conditions are shown using both simple and more complex field simulations. A relative accuracy of 10.1% is obtained...

GALAXIES IN ΛCDM WITH HALO ABUNDANCE MATCHING: LUMINOSITY-VELOCITY RELATION, BARYONIC MASS-VELOCITY RELATION, VELOCITY FUNCTION, AND CLUSTERING

International Nuclear Information System (INIS)

Trujillo-Gomez, Sebastian; Klypin, Anatoly; Primack, Joel; Romanowsky, Aaron J.

2011-01-01

It has long been regarded as difficult if not impossible for a cosmological model to account simultaneously for the galaxy luminosity, mass, and velocity distributions. We revisit this issue using a modern compilation of observational data along with the best available large-scale cosmological simulation of dark matter (DM). We find that the standard cosmological model, used in conjunction with halo abundance matching (HAM) and simple dynamical corrections, fits—at least on average—all basic statistics of galaxies with circular velocities V circ > 80 km s –1 calculated at a radius of ∼10 kpc. Our primary observational constraint is the luminosity-velocity (LV) relation—which generalizes the Tully-Fisher and Faber-Jackson relations in allowing all types of galaxies to be included, and provides a fundamental benchmark to be reproduced by any theory of galaxy formation. We have compiled data for a variety of galaxies ranging from dwarf irregulars to giant ellipticals. The data present a clear monotonic LV relation from ∼50 km s –1 to ∼500 km s –1 , with a bend below ∼80 km s –1 and a systematic offset between late- and early-type galaxies. For comparison to theory, we employ our new ΛCDM 'Bolshoi' simulation of DM, which has unprecedented mass and force resolution over a large cosmological volume, while using an up-to-date set of cosmological parameters. We use HAM to assign rank-ordered galaxy luminosities to the DM halos, a procedure that automatically fits the empirical luminosity function and provides a predicted LV relation that can be checked against observations. The adiabatic contraction of DM halos in response to the infall of the baryons is included as an optional model ingredient. The resulting predictions for the LV relation are in excellent agreement with the available data on both early-type and late-type galaxies for the luminosity range from M r = –14 to M r = –22. We also compare our predictions for the 'cold' baryon mass (i

Doppler Lidar Vertical Velocity Statistics Value-Added Product

Energy Technology Data Exchange (ETDEWEB)

Newsom, R. K. [DOE ARM Climate Research Facility, Washington, DC (United States); Sivaraman, C. [DOE ARM Climate Research Facility, Washington, DC (United States); Shippert, T. R. [DOE ARM Climate Research Facility, Washington, DC (United States); Riihimaki, L. D. [DOE ARM Climate Research Facility, Washington, DC (United States)

2015-07-01

Accurate height-resolved measurements of higher-order statistical moments of vertical velocity fluctuations are crucial for improved understanding of turbulent mixing and diffusion, convective initiation, and cloud life cycles. The Atmospheric Radiation Measurement (ARM) Climate Research Facility operates coherent Doppler lidar systems at several sites around the globe. These instruments provide measurements of clear-air vertical velocity profiles in the lower troposphere with a nominal temporal resolution of 1 sec and height resolution of 30 m. The purpose of the Doppler lidar vertical velocity statistics (DLWSTATS) value-added product (VAP) is to produce height- and time-resolved estimates of vertical velocity variance, skewness, and kurtosis from these raw measurements. The VAP also produces estimates of cloud properties, including cloud-base height (CBH), cloud frequency, cloud-base vertical velocity, and cloud-base updraft fraction.

Evolution of velocity dispersion along cold collisionless flows

International Nuclear Information System (INIS)

Banik, Nilanjan; Sikivie, Pierre

2016-01-01

We found that the infall of cold dark matter onto a galaxy produces cold collisionless flows and caustics in its halo. If a signal is found in the cavity detector of dark matter axions, the flows will be readily apparent as peaks in the energy spectrum of photons from axion conversion, allowing the densities, velocity vectors and velocity dispersions of the flows to be determined. We also discuss the evolution of velocity dispersion along cold collisionless flows in one and two dimensions. A technique is presented for obtaining the leading behaviour of the velocity dispersion near caustics. The results are used to derive an upper limit on the energy dispersion of the Big Flow from the sharpness of its nearby caustic, and a prediction for the dispersions in its velocity components

Ultrasonic velocity measurements in expanded liquid mercury

International Nuclear Information System (INIS)

Suzuki, K.; Inutake, M.; Fujiwaka, S.

1977-10-01

In this paper we present the first results of the sound velocity measurements in expanded liquid mercury. The measurements were made at temperatures up to 1600 0 C and pressures up to 1700 kg/cm 2 by means of an ultrasonic pulse transmission/echo technique which was newly developed for such high temperature/pressure condition. When the density is larger than 9 g/cm 3 , the observed sound velocity decreases linearly with decreasing density. At densities smaller than 9 g/cm 3 , the linear dependence on the density is no longer observed. The observed sound velocity approaches a minimum near the liquid-gas critical point (rho sub(cr) asymptotically equals 5.5 g/cm 3 ). The existing theories for sound velocity in liquid metals fail to explain the observed results. (auth.)

Results of verification and investigation of wind velocity field forecast. Verification of wind velocity field forecast model

International Nuclear Information System (INIS)

Ogawa, Takeshi; Kayano, Mitsunaga; Kikuchi, Hideo; Abe, Takeo; Saga, Kyoji

1995-01-01

In Environmental Radioactivity Research Institute, the verification and investigation of the wind velocity field forecast model 'EXPRESS-1' have been carried out since 1991. In fiscal year 1994, as the general analysis, the validity of weather observation data, the local features of wind field, and the validity of the positions of monitoring stations were investigated. The EXPRESS which adopted 500 m mesh so far was improved to 250 m mesh, and the heightening of forecast accuracy was examined, and the comparison with another wind velocity field forecast model 'SPEEDI' was carried out. As the results, there are the places where the correlation with other points of measurement is high and low, and it was found that for the forecast of wind velocity field, by excluding the data of the points with low correlation or installing simplified observation stations to take their data in, the forecast accuracy is improved. The outline of the investigation, the general analysis of weather observation data and the improvements of wind velocity field forecast model and forecast accuracy are reported. (K.I.)

Measurement of vortex velocities over a wide range of vortex age, downstream distance and free stream velocity

Science.gov (United States)

Rorke, J. B.; Moffett, R. C.

1977-01-01

A wind tunnel test was conducted to obtain vortex velocity signatures over a wide parameter range encompassing the data conditions of several previous researchers while maintaining a common instrumentation and test facility. The generating wing panel was configured with both a revolved airfoil tip shape and a square tip shape and had a semispan aspect of 4.05/1.0 with a 121.9 cm span. Free stream velocity was varied from 6.1 m/sec to 76.2 m/sec and the vortex core velocities were measured at locations 3, 6, 12, 24 and 48 chordlengths downstream of the wing trailing edge, yielding vortex ages up to 2.0 seconds. Wing pitch angles of 6, 8, 9 and 12 deg were investigated. Detailed surface pressure distributions and wing force measurements were obtained for each wing tip configuration. Correlation with vortex velocity data taken in previous experiments is good. During the rollup process, vortex core parameters appear to be dependent primarily on vortex age. Trending in the plateau and decay regions is more complex and the machanisms appear to be more unstable.

Effects of muscarinic M1 and M4 acetylcholine receptor stimulation on extinction and reinstatement of cocaine seeking in male mice, independent of extinction learning.

Science.gov (United States)

Stoll, Kevin; Hart, Rachel; Lindsley, Craig W; Thomsen, Morgane

2018-03-01

Stimulating muscarinic M 1 /M 4 receptors can blunt reinforcing and other effects of cocaine. A hallmark of addiction is continued drug seeking/craving after abstinence and relapse. We tested whether stimulating M 1 and/or M 4 receptors could facilitate extinction of cocaine seeking, and whether this was mediated via memory consolidation. Experimentally naïve C57BL/6J mice were allowed to acquire self-administration of intravenous cocaine (1 mg/kg/infusion) under a fixed-ratio 1 schedule of reinforcement. Then, saline was substituted for cocaine until responding extinguished to ≤30% of cocaine-reinforced responding. Immediately after each extinction session, mice received saline, the M 1 /M 4 receptor-preferring agonist xanomeline, the M 1 receptor-selective allosteric agonist VU0357017, the M 4 receptor-selective positive allosteric modulator VU0152100, or VU0357017 + VU0152100. In additional experiments, xanomeline was administered delayed after the session or in the home cage before extinction training began. In the latter group, reinstatement of responding by a 10-mg/kg cocaine injection was also tested. Stimulating M 1  + M 4 receptors significantly expedited extinction from 17.2 sessions to 8.3 using xanomeline or 7.8 using VU0357017 + VU0152100. VU0357017 alone and VU0152100 alone did not significantly modify rates of extinction (12.6 and 14.6 sessions). The effect of xanomeline was fully preserved when administered delayed after or unpaired from extinction sessions (7.5 and 6.4 sessions). Xanomeline-treated mice showed no cocaine-induced reinstatement. These findings show that M 1 /M 4 receptor stimulation can decrease cocaine seeking in mice. The effect lasted beyond treatment duration and was not dependent upon extinction learning. This suggests that M 1 /M 4 receptor stimulation modulated or reversed some neurochemical effects of cocaine exposure.

Continuous measurements of in-bore projectile velocity

International Nuclear Information System (INIS)

Asay, J.R.; Konrad, C.H.; Hall, C.A.; Shahinpoor, M.

1989-01-01

The application of velocity interferometry to the continuous measurement of in-bore projectile velocity in a small-bore three-stage railgun is described. These measurements are useful for determining projectile acceleration and for evaluating gun performance. The launcher employed in these studies consists of a two-stage light gas gun used to inject projectiles into a railgun for additional acceleration. Results obtained for projectile velocities to 7.4 km/s with the two-stage injector are reported and potential improvements for railgun applications are discussed

Spontaneous delayed migration/shortening of the pipeline embolization device: report of 5 cases.

Science.gov (United States)

Chalouhi, N; Tjoumakaris, S I; Gonzalez, L F; Hasan, D; Pema, P J; Gould, G; Rosenwasser, R H; Jabbour, P M

2013-12-01

Five patients were found to have spontaneous delayed migration/shortening of their Pipeline Embolization Devices on follow-up angiography. The device migrated proximally in 4 patients and distally in 1 patient. One patient had a subarachnoid hemorrhage and died as a result of migration of the Pipeline Embolization Device, and another patient presented with complete MCA occlusion and was left severely disabled. Mismatch in arterial diameter between inflow and outflow vessels was a constant finding. Migration of the Pipeline Embolization Device was managed conservatively, with additional placement of the device, or with parent vessel occlusion. Obtaining complete expansion of the embolization device by using a longer device, increasing vessel coverage, using adjunctive aneurysm coiling, and avoiding dragging and stretching of the device are important preventive measures. Neurointerventionalists should be aware of this potentially fatal complication and take all necessary preventive measures.

Angle independent velocity spectrum determination

DEFF Research Database (Denmark)

2014-01-01

An ultrasound imaging system (100) includes a transducer array (102) that emits an ultrasound beam and produces at least one transverse pulse-echo field that oscillates in a direction transverse to the emitted ultrasound beam and that receive echoes produced in response thereto and a spectral vel...... velocity estimator (110) that determines a velocity spectrum for flowing structure, which flows at an angle of 90 degrees and flows at angles less than 90 degrees with respect to the emitted ultrasound beam, based on the received echoes....

Pulsar velocity observations: Correlations, interpretations, and discussion

International Nuclear Information System (INIS)

Helfand, D.J.; Tademaru, E.

1977-01-01

From an examination of the current sample of 12 pulsars with measured proper motions and the z-distribution of the much larger group of over 80 sources with measured period derivatives, we develop a self-consistent picture of pulsar evolution. The apparent tendency of pulsars to move parallel to the galactic plane is explained as the result of various selection effects. A method for calculating the unmeasurable radial velocity of a pulsar is presented; it is shown that the total space velocities thus obtained are consistent with the assumption of an extreme Population I origin for pulsars which subsequently move away from the plane with a large range of velocities. The time scale for pulsar magnetic field decay is derived from dynamical considerations. A strong correlation of the original pulsar field strength with the magnitude of pulsar velocity is discussed. This results in the division of pulsars into two classes: Class A sources characterized by low space velocities, a small scale height, and low values of P 0 P 0 ; and Class B sources with a large range of velocities (up to 1000 km s -1 ), a much greater scale height, and larger values of initial field strength. It is postulated that Class A sources originate in tight binaries where their impulse acceleration at birth is insufficient to remove them from the system, while the Class B sources arise from single stars or loosely bound binaries and are accelerated to high velocities by their asymmetric radiation force. The evolutionary picture which is developed is shown to be consistent with a number of constraints imposed by supernova rates, the relative frequency of massive binaries and Class A sources, theoretical field-decay times, and the overall pulsar galactic distribution

Microseismic Velocity Imaging of the Fracturing Zone

Science.gov (United States)

Zhang, H.; Chen, Y.

2015-12-01

Hydraulic fracturing of low permeability reservoirs can induce microseismic events during fracture development. For this reason, microseismic monitoring using sensors on surface or in borehole have been widely used to delineate fracture spatial distribution and to understand fracturing mechanisms. It is often the case that the stimulated reservoir volume (SRV) is determined solely based on microseismic locations. However, it is known that for some fracture development stage, long period long duration events, instead of microseismic events may be associated. In addition, because microseismic events are essentially weak and there exist different sources of noise during monitoring, some microseismic events could not be detected and thus located. Therefore the estimation of the SRV is biased if it is solely determined by microseismic locations. With the existence of fluids and fractures, the seismic velocity of reservoir layers will be decreased. Based on this fact, we have developed a near real time seismic velocity tomography method to characterize velocity changes associated with fracturing process. The method is based on double-difference seismic tomography algorithm to image the fracturing zone where microseismic events occur by using differential arrival times from microseismic event pairs. To take into account varying data distribution for different fracking stages, the method solves the velocity model in the wavelet domain so that different scales of model features can be obtained according to different data distribution. We have applied this real time tomography method to both acoustic emission data from lab experiment and microseismic data from a downhole microseismic monitoring project for shale gas hydraulic fracturing treatment. The tomography results from lab data clearly show the velocity changes associated with different rock fracturing stages. For the field data application, it shows that microseismic events are located in low velocity anomalies. By

Surface Wave Velocity-Stress Relationship in Uniaxially Loaded Concrete

DEFF Research Database (Denmark)

Shokouhi, Parisa; Zoëga, Andreas; Wiggenhauser, Herbert

2012-01-01

The sonic surface wave (or Rayleigh wave) velocity measured on prismatic concrete specimens under uniaxial compression was found to be highly stress-dependent. At low stress levels, the acoustoelastic effect and the closure of existing microcracks results in a gradual increase in surface wave...... velocities. At higher stress levels, concrete suffers irrecoverable damage: the existing microcracks widen and coalesce and new microcracks form. This progressive damage process leads first to the flattening and eventually the drop in the velocity-stress curves. Measurements on specimens undergoing several...... loading cycles revealed that the velocities show a stress-memory effect in good agreement with the Kaiser effect. Comparing the velocities measured during loading and unloading, the effects of stress and damage on the measured velocities could be differentiated. Moreover, the stress dependency of surface...

VELOCITY VARIATIONS IN THE PHOENIX–HERMUS STAR STREAM

Energy Technology Data Exchange (ETDEWEB)

Carlberg, R. G. [Department of Astronomy and Astrophysics, University of Toronto, Toronto, ON M5S 3H4 (Canada); Grillmair, C. J., E-mail: carlberg@astro.utoronto.ca, E-mail: carl@ipac.caltech.edu [Spitzer Science Center, 1200 E. California Blvd., Pasadena, CA 91125 (United States)

2016-10-20

Measurements of velocity and density perturbations along stellar streams in the Milky Way provide a time-integrated measure of dark matter substructure at larger galactic radius than the complementary instantaneous inner-halo strong lensing detection of dark matter sub-halos in distant galaxies. An interesting case to consider is the proposed Phoenix–Hermus star stream, which is long, thin, and on a nearly circular orbit, making it a particular good target to study for velocity variations along its length. In the presence of dark matter sub-halos, the stream velocities are significantly perturbed in a manner that is readily understood with the impulse approximation. A set of simulations shows that only sub-halos above a few 10{sup 7} M {sub ⊙} lead to reasonably long-lived observationally detectable velocity variations of amplitude of order 1 km s{sup −1}, with an average of about one visible hit per (two-armed) stream over a 3 Gyr interval. An implication is that globular clusters themselves will not have a visible impact on the stream. Radial velocities have the benefit of being completely insensitive to distance errors. Distance errors scatter individual star velocities perpendicular and tangential to the mean orbit, but their mean values remain unbiased. Calculations like these help build the quantitative case to acquire large, fairly deep, precision velocity samples of stream stars.

EVOLUTION OF ROTATIONAL VELOCITIES OF A-TYPE STARS

International Nuclear Information System (INIS)

Yang Wuming; Bi Shaolan; Tian Zhijia; Meng Xiangcun

2013-01-01

The equatorial velocity of A-type stars undergoes an acceleration in the first third of the main sequence (MS) stage, but the velocity decreases as if the stars were not undergoing any redistribution of angular momentum in the external layers in the last stage of the MS phase. Our calculations show that the acceleration and the decrease of the equatorial velocity can be reproduced by the evolution of the differential rotation zero-age MS model with the angular momentum transport caused by hydrodynamic instabilities during the MS stage. The acceleration results from the fact that the angular momentum stored in the interiors of the stars is transported outward. In the last stage, the core and the radiative envelope are uncoupling, and the rotation of the envelope is a quasi-solid rotation; the uncoupling and the expansion of the envelope indicate that the decrease of the equatorial velocity approximately follows the slope for the change in the equatorial velocity of the model without any redistribution of angular momentum. When the fractional age 0.3 ∼ MS ∼< 0.5, the equatorial velocity remains almost constant for stars whose central density increases with age in the early stage of the MS phase, while the velocity decreases with age for stars whose central density decreases with age in the early stage of the MS phase.

Analysis of the swimming velocity of cadmium-stressed Daphnia magna

International Nuclear Information System (INIS)

Baillieul, M.; Blust, R.

1999-01-01

The swimming velocity of the waterflea Daphnia magna is dependent on its body size. Therefore, environmental factors like toxic stress that influence growth also influence swimming velocity. An experiment was set up to test whether exposure to cadmium would reduce only growth, with a concomitant decrease in velocity, or whether it would reduce velocity below the swimming velocity of similarly-sized control animals. Daphnids were exposed for 10 days to free cadmium ion concentrations ranging from 1x10 -8 to 1x10 -7 M Cd 2+ , and body size and swimming velocity were measured every 2 days. The results showed that cadmium decreased both growth and velocity, i.e. exposed daphnids swam slower than similarly-sized control daphnids. Swimming velocity provided no indication of successful acclimation in any cadmium treatment. Food consumption and assimilation were reduced by exposure to cadmium. This reduced food intake may have, at least partially, caused the decreased growth rates. However, since reduced food intake does not affect swimming velocity, the reduced swimming velocity must be attributed to toxic effects of cadmium, other than those on food intake. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

Variable exhumation rates and variable displacement rates: Documenting recent slowing of Himalayan shortening in western Bhutan

Science.gov (United States)

McQuarrie, Nadine; Tobgay, Tobgay; Long, Sean P.; Reiners, Peter W.; Cosca, Michael A.

2014-01-01

We link exhumational variability in space and time to the evolving geometry of the Himalayan fold–thrust belt in western Bhutan. By combining new and published geochronologic and thermochronologic data we document the burial age, peak temperatures and complete cooling history from 20 Ma to the present over an across-strike distance of ∼125 km. These integrated cooling curves highlight windows of fast exhumation that vary spatially and temporally. We propose that pulses of fast exhumation are a result of structures that facilitate the vertical motion of material, illustrated in sequentially-restored cross sections. Due to a range of permissible geometries at depth, we explore and evaluate the impact of geometry on kinematics and rates of deformation. The linked cooling history and cross sections provide estimates of both magnitude and timing of thrust sheet displacement and highlight temporal variability in potential shortening rates. Structural and chronologic data illustrate a general north to south progression of Himalayan deformation, with emplacement of the Main Central thrust (MCT), Paro thrust and Shumar thrust by 12 to no later than 9 Ma. Two different geometries and kinematic scenarios for the Lesser Himalayan duplex are proposed. A north to south propagating duplex system requires that the southern portion of that system, south of the MCT, deformed and cooled by 9 Ma, leaving only the southernmost thrust sheets, including the Main Boundary and Main Frontal thrusts, to deform between 9 and 0 Ma. This limited post 9 Ma shortening would necessitate a marked slowdown in convergence accommodated on the Main Himalayan thrust. A two-tiered duplex system, which allows for the Paro window duplex and the southern Baxa duplex to form simultaneously, permits duplex formation and accompanying exhumation until 6 Ma. Limited cooling from ∼200 °C to the surface post 6 Ma suggests either a decrease in shortening rates from 6 to 0 Ma or that duplex formation and

Sound velocity in potassium hydroxide aqueous solution

International Nuclear Information System (INIS)

Tsapuryan, Kh.D.; Aleksandrov, A.A.; Kochetkov, A.I.

1992-01-01

Measurements of ultrasonic velocities in potassium hydroxide aqueous solutions are carried out within the frames of studies on improvement of water chemistry in NPP cooling systems. Method of echo pulses superposition with acoustic path length of 41.447 mm is used for measurements. The measurements are performed at 2.6 MHz frequency. Complex temperature dependence of ultrasonic velocity is determined. Ultrasonic velocity dependence on pressure is close to linear one. The formula for calculation of thermodynamic properties of the studied solutions on the basis of experimental data obtained is proposed

Shuttlecock Velocity of a Badminton Drop Shot

Directory of Open Access Journals (Sweden)

Ampharin Ongvises

2013-01-01

Full Text Available In a badminton ‘drop shot’, the shuttlecock is struck by a non-rotating racquet at low speed. In this investigation, a shuttlecock was hit by a badminton racquet in a linear collision, simulating a drop shot. The collision was recorded with high-speed video and the velocities of the racquet and shuttlecock determined. The relationship between the impact velocity of the racquet and the velocity of the shuttlecock as it leaves the badminton racquet after collision was found to be proportional over the range tested.

Shuttlecock Velocity of a Badminton Drop Shot

Directory of Open Access Journals (Sweden)

Ampharin Ongvises

2013-12-01

Full Text Available In a badminton ‘drop shot’, the shuttlecock is struck by a non-rotating racquet at low speed. In this investigation, a shuttlecock was hit by a badminton racquet in a linear collision, simulating a drop shot. The collision was recorded with high-speed video and the velocities of the racquet and shuttlecock determined. The relationship between the impact velocity of the racquet and the velocity of the shuttlecock as it leaves the badminton racquet after collision was found to be proportional over the range tested.

Muscle Force-Velocity Relationships Observed in Four Different Functional Tests.

Science.gov (United States)

Zivkovic, Milena Z; Djuric, Sasa; Cuk, Ivan; Suzovic, Dejan; Jaric, Slobodan

2017-02-01

The aims of the present study were to investigate the shape and strength of the force-velocity relationships observed in different functional movement tests and explore the parameters depicting force, velocity and power producing capacities of the tested muscles. Twelve subjects were tested on maximum performance in vertical jumps, cycling, bench press throws, and bench pulls performed against different loads. Thereafter, both the averaged and maximum force and velocity variables recorded from individual trials were used for force-velocity relationship modeling. The observed individual force-velocity relationships were exceptionally strong (median correlation coefficients ranged from r = 0.930 to r = 0.995) and approximately linear independently of the test and variable type. Most of the relationship parameters observed from the averaged and maximum force and velocity variable types were strongly related in all tests (r = 0.789-0.991), except for those in vertical jumps (r = 0.485-0.930). However, the generalizability of the force-velocity relationship parameters depicting maximum force, velocity and power of the tested muscles across different tests was inconsistent and on average moderate. We concluded that the linear force-velocity relationship model based on either maximum or averaged force-velocity data could provide the outcomes depicting force, velocity and power generating capacity of the tested muscles, although such outcomes can only be partially generalized across different muscles.

Experimental study of the spatial distribution of the velocity field of sedimenting particles: mean velocity, pseudo-turbulent fluctuations, intrinsic convection

International Nuclear Information System (INIS)

Bernard-Michel, G.

2001-01-01

This work follows previous experiments from Nicolai et al. (95), Peysson and Guazzelli (98) and Segre et al. (97), which consisted in measures of the velocity of particles sedimenting in a liquid at low particular Reynolds numbers. Our goal, introduced in the first part with a bibliographic study, is to determinate the particles velocity fluctuations properties. The fluctuations are indeed of the same order as the mean velocity. We are proceeding with PIV Eulerian measures. The method is described in the second part. Its originality comes from measures obtained in a thin laser light sheet, from one side to the other of the cells, with a square section: the measures are therefore spatially localised. Four sets of cells and three sets of particles were used, giving access to ratios 'cell width over particle radius' ranging from about 50 up to 800. In the third part, we present the results concerning the velocity fluctuations structure and their spatial distribution. The intrinsic convection between to parallel vertical walls is also studied. The velocity fluctuations are organised in eddy structures. Their size (measured with correlation length) is independent of the volume fraction, contradicting the results of Segre et al. (97). The results concerning the velocity fluctuations spatial profiles - from one side to the other of the cell - confirm those published by Peysson and Guazzelli (98) in the case of stronger dilution. The evolution of the spatial mean velocity fluctuations confirms the results obtained by Segre et al. (97). The intrinsic convection is also observed in the case of strong dilutions. (author)

Cosmological streaming velocities and large-scale density maxima

International Nuclear Information System (INIS)

Peacock, J.A.; Lumsden, S.L.; Heavens, A.F.

1987-01-01

The statistical testing of models for galaxy formation against the observed peculiar velocities on 10-100 Mpc scales is considered. If it is assumed that observers are likely to be sited near maxima in the primordial field of density perturbations, then the observed filtered velocity field will be biased to low values by comparison with a point selected at random. This helps to explain how the peculiar velocities (relative to the microwave background) of the local supercluster and the Rubin-Ford shell can be so similar in magnitude. Using this assumption to predict peculiar velocities on two scales, we test models with large-scale damping (i.e. adiabatic perturbations). Allowed models have a damping length close to the Rubin-Ford scale and are mildly non-linear. Both purely baryonic universes and universes dominated by massive neutrinos can account for the observed velocities, provided 0.1 ≤ Ω ≤ 1. (author)

Different velocities in wave trains: early definitions and interpretations

International Nuclear Information System (INIS)

Lombardi, Anna M

2002-01-01

Recent experiments force us to re-examine the physical significance of the different velocities which one can introduce to describe the propagation of a wave train. In this paper we collect together the early definitions of these velocities, and their physical interpretations, dating back to the end of the 19th and to the first decades of the 20th century. Our purpose is to examine the scientific contexts in which some relevant definitions of velocities emerged, with particular attention paid to the early definitions of the group velocity. We recall some debates in which the group velocity had a dominant role, in order to follow the evolution of the physical meanings that have been ascribed to it. Finally, we focus our attention on the connection between the introduction of the group velocity and the problem of white light

Analyses of Current And Wave Forces on Velocity Caps

DEFF Research Database (Denmark)

Christensen, Erik Damgaard; Buhrkall, Jeppe; Eskesen, Mark C. D.

2015-01-01

Velocity caps are often used in connection with for instance offshore intake sea water for the use of for cooling water for power plants or as a source for desalinization plants. The intakes can also be used for river intakes. The velocity cap is placed on top of a vertical pipe. The vertical pipe......) this paper investigates the current and wave forces on the velocity cap and the vertical cylinder. The Morison’s force model was used in the analyses of the extracted force time series in from the CFD model. Further the distribution of the inlet velocities around the velocity cap was also analyzed in detail...

STARE velocities: 2. Evening westward electron flow

Directory of Open Access Journals (Sweden)

M. Uspensky

2004-04-01

Full Text Available Four evening events and one morning event of joint EISCAT/STARE observations during ~22h are considered and the differences between observed STARE line-of-sight (l-o-s velocities and EISCAT electron drift velocities projected onto the STARE beams are studied. We demonstrate that the double-pulse technique, which is currently in use in the STARE routine data handling, typically underestimates the true phase velocity as inferred from the multi-pulse STARE data. We show that the STARE velocities are persistently smaller (1.5–2 times than the EISCAT velocities, even for the multi-pulse data. The effect seems to be more pronounced in the evening sector when the Finland radar observes at large flow angles. We evaluate the performance of the ion-acoustic approach (IAA, Nielsen and Schlegel, 1985 and the off-orthogonal fluid approach (OOFA, Uspensky et al., 2003 techniques to predict the true electron drift velocity for the base event of 12 February 1999. The IAA technique predicts the convection reasonably well for enhanced flows of >~1000m/s, but not so well for slower ones. By considering the EISCAT N(h profiles, we derive the effective aspect angle and effective altitude of backscatter, and use this information for application of the OOFA technique. We demonstrate that the OOFA predictions for the base event are superior over the IAA predictions and thus, we confirm that OOFA predicts the electron velocities reasonably well in the evening sector, in addition to the morning sector, as concluded by Uspensky et al. (2003. To check how "robust" the OOFA model is and how successful it is for convection estimates without the EISCAT support, we analysed three additional evening events and one additional morning event for which information on N(h profiles was intentionally ignored. By accepting the mean STARE/EISCAT velocity ratio of 0.55 and the mean azimuth rotation of 9° (derived for the basic event, we show that the OOFA performs

Temperature dependence of sound velocity in yttrium ferrite

International Nuclear Information System (INIS)

L'vov, V.A.

1979-01-01

The effect of the phonon-magnon and phonon-phonon interoctions on the temperature dependence of the longitudinal sound velocity in yttrium ferrite is considered. It has been shown that at low temperatures four-particle phonon-magnon processes produce the basic contribution to renormalization of the sound velocity. At higher temperatures the temperature dependence of the sound velocity is mainly defined by phonon-phonon processes

Spectral Velocity Estimation in the Transverse Direction

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt

2013-01-01

A method for estimating the velocity spectrum for a fully transverse flow at a beam-to-flow angle of 90is described. The approach is based on the transverse oscillation (TO) method, where an oscillation across the ultrasound beam is made during receive processing. A fourth-order estimator based...... on the correlation of the received signal is derived. A Fourier transform of the correlation signal yields the velocity spectrum. Performing the estimation for short data segments gives the velocity spectrum as a function of time as for ordinary spectrograms, and it also works for a beam-to-flow angle of 90...... estimation scheme can reliably find the spectrum at 90, where a traditional estimator yields zero velocity. Measurements have been conducted with the SARUS experimental scanner and a BK 8820e convex array transducer (BK Medical, Herlev, Denmark). A CompuFlow 1000 (Shelley Automation, Inc, Toronto, Canada...

Flocking and invariance of velocity angles.

Science.gov (United States)

Liu, Le; Huang, Lihong; Wu, Jianhong

2016-04-01

Motsch and Tadmor considered an extended Cucker-Smale model to investigate the flocking behavior of self-organized systems of interacting species. In this extended model, a cone of the vision was introduced so that outside the cone the influence of one agent on the other is lost and hence the corresponding influence function takes the value zero. This creates a problem to apply the Motsch-Tadmor and Cucker-Smale method to prove the flocking property of the system. Here, we examine the variation of the velocity angles between two arbitrary agents, and obtain a monotonicity property for the maximum cone of velocity angles. This monotonicity permits us to utilize existing arguments to show the flocking property of the system under consideration, when the initial velocity angles satisfy some minor technical constraints.

Direct Investigation of Velocity Overshoot in the Femtosecond Regime

Science.gov (United States)

1990-01-25

by block nuinber) The experiental study ofsubpicsecond transport in GaAs and other semionductors is of fundmental inPortanoe for the understanding of...velocities, hence in principle this measurement can yield information about velocity 5 overshoot phenomenon. An electric field will modify photon absorption in...3.1.2 are the best fit of the theory assuming a constant electron velocity. The constant-velocity model cannot account for the data at 14 and 22kV/cm

Analyses of hydraulic performance of velocity caps

DEFF Research Database (Denmark)

Christensen, Erik Damgaard; Degn Eskesen, Mark Chr.; Buhrkall, Jeppe

2014-01-01

The hydraulic performance of a velocity cap has been investigated. Velocity caps are often used in connection with offshore intakes. CFD (computational fluid dynamics) examined the flow through the cap openings and further down into the intake pipes. This was combined with dimension analyses...

Velocity-space sensitivity of neutron spectrometry measurements

DEFF Research Database (Denmark)

Jacobsen, Asger Schou; Salewski, Mirko; Eriksson, J.

2015-01-01

Neutron emission spectrometry (NES) measures the energies of neutrons produced in fusion reactions. Here we present velocity-space weight functions for NES and neutron yield measurements. Weight functions show the sensitivity as well as the accessible regions in velocity space for a given range...

A comparative study of calculated and measured particle velocities

International Nuclear Information System (INIS)

Tariq, S.M.

2005-01-01

After an explosive is detonated in a blast hole, seismic waves are generated in the ground surrounding the blast hole. These waves cause the particles of rock to oscillate about its position. As the wave attenuate, the particles come back to their original position. The rapidity with which the particles move is called the particle velocity. The peak or maximum velocity is the value which is of prime concern. This value of peak particle velocity can be estimated by the equations determined by the United States Bureau of Mines and by the DUPONT. A research program was conducted by the author at the 'Beck Materials Quarry' situated near Rolla, Missouri, USA. The purpose was to draw a comparison between the predicted and measured particle velocities. It was generally found that the predicted peak particle velocities were quite high as compared to the velocities measured by the Seismographs. (author)

Superconducting spoke cavities for high-velocity applications

Energy Technology Data Exchange (ETDEWEB)

Hopper, Christopher S. [Old Dominion U.; Delayen, Jean R. [Old Dominion U., JLAB

2013-10-01

To date, superconducting spoke cavities have been designed, developed, and tested for particle velocities up to {beta}{sub 0}~0.6, but there is a growing interest in possible applications of multispoke cavities for high-velocity applications. We have explored the design parameter space for low-frequency, high-velocity, double-spoke superconducting cavities in order to determine how each design parameter affects the electromagnetic properties, in particular the surface electromagnetic fields and the shunt impedance. We present detailed design for cavities operating at 325 and 352 MHz and optimized for {beta}{sub 0}~=0.82 and 1.

Chalk porosity and sonic velocity versus burial depth

DEFF Research Database (Denmark)

Fabricius, Ida Lykke; Gommesen, Lars; Krogsbøll, Anette Susanne

2008-01-01

Seventy chalk samples from four formations in the overpressured Danish central North Sea have been analyzed to investigate how correlations of porosity and sonic velocity with burial depth are affected by varying mineralogy, fluid pressure, and early introduction of petroleum. The results show th...... for fluid pressure because the cementing ions originate from stylolites, which are mechanically similar to fractures. We find that cementation occurs over a relatively short depth interval.......Seventy chalk samples from four formations in the overpressured Danish central North Sea have been analyzed to investigate how correlations of porosity and sonic velocity with burial depth are affected by varying mineralogy, fluid pressure, and early introduction of petroleum. The results show...... that porosity and sonic velocity follow the most consistent depth trends when fluid pressure and pore-volume compressibility are considered. Quartz content up to 10% has no marked effect, but more than 5% clay causes lower porosity and velocity. The mineralogical effect differs between P-wave and shear velocity...

Optic-microwave mixing velocimeter for superhigh velocity measurement

International Nuclear Information System (INIS)

Weng Jidong; Wang Xiang; Tao Tianjiong; Liu Cangli; Tan Hua

2011-01-01

The phenomenon that a light beam reflected off a moving object experiences a Doppler shift in its frequency underlies practical interferometric techniques for remote velocity measurements, such as velocity interferometer system for any reflector (VISAR), displacement interferometer system for any reflector (DISAR), and photonic Doppler velocimetry (PDV). While VISAR velocimeters are often bewildered by the fringe loss upon high-acceleration dynamic process diagnosis, the optic-fiber velocimeters such as DISAR and PDV, on the other hand, are puzzled by high velocity measurement over 10 km/s, due to the demand for the high bandwidth digitizer. Here, we describe a new optic-microwave mixing velocimeter (OMV) for super-high velocity measurements. By using currently available commercial microwave products, we have constructed a simple, compact, and reliable OMV device, and have successfully obtained, with a digitizer of bandwidth 6 GH only, the precise velocity history of an aluminum flyer plate being accelerated up to 11.2 km/s in a three stage gas-gun experiment.

An improved estimation and focusing scheme for vector velocity estimation

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt; Munk, Peter

1999-01-01

to reduce spatial velocity dispersion. Examples of different velocity vector conditions are shown using the Field II simulation program. A relative accuracy of 10.1 % is obtained for the lateral velocity estimates for a parabolic velocity profile for a flow perpendicular to the ultrasound beam and a signal...

Surface wave velocity tracking by bisection method

International Nuclear Information System (INIS)

Maeda, T.

2005-01-01

Calculation of surface wave velocity is a classic problem dating back to the well-known Haskell's transfer matrix method, which contributes to solutions of elastic wave propagation, global subsurface structure evaluation by simulating observed earthquake group velocities, and on-site evaluation of subsurface structure by simulating phase velocity dispersion curves and/or H/V spectra obtained by micro-tremor observation. Recently inversion analysis on micro-tremor observation requires efficient method of generating many model candidates and also stable, accurate, and fast computation of dispersion curves and Raleigh wave trajectory. The original Haskell's transfer matrix method has been improved in terms of its divergence tendency mainly by the generalized transmission and reflection matrix method with formulation available for surface wave velocity; however, root finding algorithm has not been fully discussed except for the one by setting threshold to the absolute value of complex characteristic functions. Since surface wave number (reciprocal to the surface wave velocity multiplied by frequency) is a root of complex valued characteristic function, it is intractable to use general root finding algorithm. We will examine characteristic function in phase plane to construct two dimensional bisection algorithm with consideration on a layer to be evaluated and algorithm for tracking roots down along frequency axis. (author)

Indentation of aluminium foam at low velocity

Directory of Open Access Journals (Sweden)

Shi Xiaopeng

2015-01-01

Full Text Available The indentation behaviour of aluminium foams at low velocity (10 m/s ∼ 30 m/s was investigated both in experiments and numerical simulation in this paper. A flat-ended indenter was used and the force-displacement history was recorded. The Split Hopkinson Pressure bar was used to obtain the indentation velocity and forces in the dynamic experiments. Because of the low strength of the aluminium foam, PMMA bar was used, and the experimental data were corrected using Bacon's method. The energy absorption characteristics varying with impact velocity were then obtained. It was found that the energy absorption ability of aluminium foam gradually increases in the quasi-static regime and shows a significant increase at ∼10 m/s velocity. Numerical simulation was also conducted to investigate this process. A 3D Voronoi model was used and models with different relative densities were investigated as well as those with different failure strain. The indentation energy increases with both the relative density and failure strain. The analysis of the FE model implies that the significant change in energy absorption ability of aluminium foam in indentation at ∼10 m/s velocity may be caused by plastic wave effect.

Jovian cloud structure and velocity fields

International Nuclear Information System (INIS)

Mitchell, J.L.; Terrile, R.J.; Collins, S.A.; Smith, B.A.; Muller, J.P.; Ingersoll, A.P.; Hunt, G.E.; Beebe, R.F.

1979-01-01

A regional comparison of the cloud structures and velocity fields (meridional as well as zonal velocities) in the jovian atmosphere (scales > 200 km) as observed by the Voyager 1 imaging system is given. It is shown that although both hemispheres of Jupiter show similar patterns of diminishing and alternating eastward and westward jets as one progresses polewards, there is a pronounced asymmetry in the structural appearance of the two hemispheres. (UK)

Thick-skinned tectonics in a Late Cretaceous-Neogene intracontinental belt (High Atlas Mountains, Morocco): The flat-ramp fault control on basement shortening and cover folding

Science.gov (United States)

Fekkak, A.; Ouanaimi, H.; Michard, A.; Soulaimani, A.; Ettachfini, E. M.; Berrada, I.; El Arabi, H.; Lagnaoui, A.; Saddiqi, O.

2018-04-01

Most of the structural studies of the intracontinental High Atlas belt of Morocco have dealt with the central part of the belt, whose basement does not crop out. Here we study the Alpine deformation of the North Subatlas Zone, which is the part of the Western High Atlas (WHA) Paleozoic Massif that involves both Paleozoic basement units and remnants of their Mesozoic-Cenozoic cover formations. Our aim is to better constrain the geometry and kinematics of the basement faults during the Alpine shortening. Based on detail mapping, satellite imagery and field observations, we describe an array of sub-equatorial, transverse and oblique faults between the WHA Axial Zone and the Haouz Neogene basin. They define a mosaic of basement blocks pushed upon one another and upon the Haouz basement along the North Atlas Fault (NAF). The Axial Zone makes up the hanging-wall of the Adassil-Medinet Fault (AMF) south of this mosaic. The faults generally presents flat-ramp-flat geometry linked to the activation of multiple décollement levels, either within the basement where its foliation is subhorizontal or within favourable cover formations (Jurassic evaporites, Lower Cretaceous silty red beds, Upper Cretaceous evaporitic marls, Neogene basal argillites). The occurrence of the North Atlas detachment (NAD) allowed folded pop-up units to develop in front of the propagating NAF. Shortening began as early as the Campanian-Maastrichtian along the AMF. The direction of the maximum horizontal stress rotated from NNE-SSW to NNW-SSE from the Maastrichtian-Paleocene to the Neogene. The amount of shortening reaches 20% in the Azegour transect. This compares with the shortening amount published for the central-eastern High Atlas, suggesting that similar structures characterize the Paleozoic basement all along the belt. The WHA thick-skinned tectonics evokes that of the frontal Sevier belt and of the external Western Alps, although with a much minor pre-inversion burial.

Liquid velocity in upward and downward air-water flows

International Nuclear Information System (INIS)

Sun Xiaodong; Paranjape, Sidharth; Kim, Seungjin; Ozar, Basar; Ishii, Mamoru

2004-01-01

Local characteristics of the liquid phase in upward and downward air-water two-phase flows were experimentally investigated in a 50.8-mm inner-diameter round pipe. An integral laser Doppler anemometry (LDA) system was used to measure the axial liquid velocity and its fluctuations. No effect of the flow direction on the liquid velocity radial profile was observed in single-phase liquid benchmark experiments. Local multi-sensor conductivity probes were used to measure the radial profiles of the bubble velocity and the void fraction. The measurement results in the upward and downward two-phase flows are compared and discussed. The results in the downward flow demonstrated that the presence of the bubbles tended to flatten the liquid velocity radial profile, and the maximum liquid velocity could occur off the pipe centerline, in particular at relatively low flow rates. However, the maximum liquid velocity always occurred at the pipe center in the upward flow. Also, noticeable turbulence enhancement due to the bubbles in the two-phase flows was observed in the current experimental flow conditions. Furthermore, the distribution parameter and the void-weighted area-averaged drift velocity were obtained based on the definitions