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Sample records for short turnaround times

  1. Perceived and Real Histopathology Turnaround Time: A Teaching ...

    African Journals Online (AJOL)

    2018-03-05

    Mar 5, 2018 ... Background: This study aims to audit analytic turnaround time (TAT) in a histopathology ... facility where not only pathology services are rendered, but residency ..... pathology as a tool for quality assurance. Niger J Med. 2008 ...

  2. Improving Reports Turnaround Time: An Essential Healthcare Quality Dimension.

    Science.gov (United States)

    Khan, Mustafa; Khalid, Parwaiz; Al-Said, Youssef; Cupler, Edward; Almorsy, Lamia; Khalifa, Mohamed

    2016-01-01

    Turnaround time is one of the most important healthcare performance indicators. King Faisal Specialist Hospital and Research Center in Jeddah, Saudi Arabia worked on reducing the reports turnaround time of the neurophysiology lab from more than two weeks to only five working days for 90% of cases. The main quality improvement methodology used was the FOCUS PDCA. Using root cause analysis, Pareto analysis and qualitative survey methods, the main factors contributing to the delay of turnaround time and the suggested improvement strategies were identified and implemented, through restructuring transcriptionists daily tasks, rescheduling physicians time and alerting for new reports, engaging consultants, consistent coordination and prioritizing critical reports. After implementation; 92% of reports are verified within 5 days compared to only 6% before implementation. 7% of reports were verified in 5 days to 2 weeks and only 1% of reports needed more than 2 weeks compared to 76% before implementation.

  3. Predicting turnaround time reductions of the diagnostic track in the histopathology laboratory using mathematical modelling

    NARCIS (Netherlands)

    Leeftink, A G; Boucherie, R J; Hans, E W; Verdaasdonk, M A M; Vliegen, I M H; van Diest, P J

    BACKGROUND: Pathology departments face a growing volume of more and more complex testing in an era where healthcare costs tend to explode and short turnaround times (TATs) are expected. In contrast, the histopathology workforce tends to shrink, so histopathology employees experience high workload

  4. Predicting turnaround time reductions of the diagnostic track in the histopathology laboratory using mathematical modelling

    NARCIS (Netherlands)

    Leeftink, Anne Greetje; Boucherie, Richardus J.; Hans, Elias W.; Verdaasdonk, M.A.M.; Vliegen, Ingrid; Van Diest, P.J

    Background Pathology departments face a growing volume of more and more complex testing in an era where healthcare costs tend to explode and short turnaround times (TATs) are expected. In contrast, the histopathology workforce tends to shrink, so histopathology employees experience high workload

  5. Perceived and Real Histopathology Turnaround Time: A Teaching ...

    African Journals Online (AJOL)

    2018-03-05

    Mar 5, 2018 ... Background: This study aims to audit analytic turnaround time (TAT) in a histopathology ... TAT was 3.6 ± 2 days, with 86.7% of reports being ready within 5 working days. ... The size of the institution, extent of automation, and number of ... advocates at least 10% rescreening of cytology slides for audit ...

  6. Turnaround Time and Market Capacity in Contract Cheating

    Science.gov (United States)

    Wallace, Melisa J.; Newton, Philip M.

    2014-01-01

    Contract cheating is the process whereby students auction off the opportunity for others to complete assignments for them. It is an apparently widespread yet under-researched problem. One suggested strategy to prevent contract cheating is to shorten the turnaround time between the release of assignment details and the submission date, thus making…

  7. Decreasing medication turnaround time with digital scanning technology in a canadian health region.

    Science.gov (United States)

    Neville, Heather; Nodwell, Lisa; Alsharif, Sahar

    2014-11-01

    Reducing medication turnaround time can improve efficiency, patient safety, and quality of care in the hospital setting. Digital scanning technology (DST) can be used to electronically transmit scanned prescriber orders to a pharmacy computer queue for verification and processing, which may help to improve medication turnaround time. To evaluate medication turnaround time before and after implementation of DST for all medications and for antibiotics only. Medication turnaround times were evaluated retrospectively for periods before (June 6-10, 2011) and after (September 26-30, 2011) implementation of DST at 2 hospital sites in 1 health region. Medication turnaround time was defined as the time from composition of a medication order by the prescriber to its verification by the pharmacy (phase 1) and the time from prescriber composition to administration to the patient by a nurse (total). Median turnaround times were analyzed with SPSS software using the Mann-Whitney U test. In total, 304 and 244 medication orders were audited before and after DST implementation, respectively. Median phase 1 turnaround time for all medications declined significantly, from 2 h 23 min before DST implementation to 1 h 33 min after DST implementation (p < 0.001). Antibiotics were also processed significantly faster (1 h 51 min versus 1 h 9 min, p = 0.015). However, total turnaround time for all medications did not differ significantly (5 h 15 min versus 5 h 0 min, p = 0.42). Implementation of DST was associated with a 50-min decrease in medication turnaround time for the period from when an order was prescribed to the time it was processed by the pharmacy. Regular evaluation of medication turnaround times is recommended to compare with benchmarks, to ensure that hospital standards are being met, and to measure the effects of policy changes and implementation of new technology on medication-use processes.

  8. Using lean principles to improve outpatient adult infusion clinic chemotherapy preparation turnaround times.

    Science.gov (United States)

    Lamm, Matthew H; Eckel, Stephen; Daniels, Rowell; Amerine, Lindsey B

    2015-07-01

    The workflow and chemotherapy preparation turnaround times at an adult infusion clinic were evaluated to identify opportunities to optimize workflow and efficiency. A three-phase study using Lean Six Sigma methodology was conducted. In phase 1, chemotherapy turnaround times in the adult infusion clinic were examined one year after the interim goal of a 45-minute turnaround time was established. Phase 2 implemented various experiments including a five-day Kaizen event, using lean principles in an effort to decrease chemotherapy preparation turnaround times in a controlled setting. Phase 3 included the implementation of process-improvement strategies identified during the Kaizen event, coupled with a final refinement of operational processes. In phase 1, the mean turnaround time for all chemotherapy preparations decreased from 60 to 44 minutes, and a mean of 52 orders for adult outpatient chemotherapy infusions was received each day. After installing new processes, the mean turnaround time had improved to 37 minutes for each chemotherapy preparation in phase 2. In phase 3, the mean turnaround time decreased from 37 to 26 minutes. The overall mean turnaround time was reduced by 26 minutes, representing a 57% decrease in turnaround times in 19 months through the elimination of waste and the implementation of lean principles. This reduction was accomplished through increased efficiencies in the workplace, with no addition of human resources. Implementation of Lean Six Sigma principles improved workflow and efficiency at an adult infusion clinic and reduced the overall chemotherapy turnaround times from 60 to 26 minutes. Copyright © 2015 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  9. Improving Autopsy Report Turnaround Times by Implementing Lean Management Principles.

    Science.gov (United States)

    Cromwell, Susan; Chiasson, David A; Cassidy, Debra; Somers, Gino R

    2018-01-01

    The autopsy is an integral part of the service of a large academic pathology department. Timely reporting is central to providing good service and is beneficial for many stakeholders, including the families, the clinical team, the hospital, and the wider community. The current study aimed to improve hospital-consented autopsy reporting times (turnaround time, TAT) by using lean principles modified for a healthcare setting, with an aim of signing out 90% of autopsies in 90 days. An audit of current and historical TATs was performed, and a working group incorporating administrative, technical, and professional staff constructed a value stream map documenting the steps involved in constructing an autopsy report. Two areas of delay were noted: examination of the microscopy and time taken to sign-out the report after the weekly autopsy conference. Several measures were implemented to address these delays, including visual tracking using a whiteboard and individualized tracking sheets, weekly whiteboard huddles, and timelier scheduling of clinicopathologic conference rounds. All measures resulted in an improvement of TATs. In the 30 months prior to the institution of lean, 37% of autopsies (53/144) were signed out in 90 days, with a wide variation in reporting times. In the 30 months following the institution of lean, this improved to 74% (136/185) ( P lean; 63 days post-lean). The application of lean principles to autopsy sign-out workflow can significantly improve TATs and reduce variability, without changing staffing levels or significantly altering scheduling structure.

  10. Discrepancies Between Planned and Actual Operating Room Turnaround Times at a Large Rural Hospital in Germany

    Directory of Open Access Journals (Sweden)

    Regula Morgenegg

    2018-01-01

    retrospective study examined the OR turnaround data of 875 elective surgery cases scheduled at the Marienhospital, Vechta, Germany, between July and October 2014. The frequency distributions of planned and actual OR turnaround times were compared and correlations between turnaround times and various factors were established, including the time of day of the procedure, patient age and the planned duration of the surgery. Results: There was a significant difference between mean planned and actual OR turnaround times (0.32 versus 0.64 hours; P <0.001. In addition, significant correlations were noted between actual OR turnaround times and the time of day of the surgery, patient age, actual duration of the procedure and staffing changes affecting the surgeon or the medical specialty of the surgery (P <0.001 each. The quotient of actual/planned OR turnaround times ranged from 1.733–3.000. Conclusion: Significant discrepancies between planned and actual OR turnaround times were noted during the study period. Such findings may be potentially used in future studies to establish a tool to improve OR planning, measure OR management performance and enable benchmarking.

  11. Factors that impact turnaround time of surgical pathology specimens in an academic institution.

    Science.gov (United States)

    Patel, Samip; Smith, Jennifer B; Kurbatova, Ekaterina; Guarner, Jeannette

    2012-09-01

    Turnaround time of laboratory results is important for customer satisfaction. The College of American Pathologists' checklist requires an analytic turnaround time of 2 days or less for most routine cases and lets every hospital define what a routine specimen is. The objective of this study was to analyze which factors impact turnaround time of nonbiopsy surgical pathology specimens. We calculated the turnaround time from receipt to verification of results (adjusted for weekends and holidays) for all nonbiopsy surgical specimens during a 2-week period. Factors studied included tissue type, number of slides per case, decalcification, immunohistochemistry, consultations with other pathologists, and diagnosis. Univariate and multivariate analyses were performed. A total of 713 specimens were analyzed, 551 (77%) were verified within 2 days and 162 (23%) in 3 days or more. Lung, gastrointestinal, breast, and genitourinary specimens showed the highest percentage of cases being signed out in over 3 days. Diagnosis of malignancy (including staging of the neoplasia), consultation with other pathologists, having had a frozen section, and use of immunohistochemical stains were significantly associated with increased turnaround time in univariate analysis. Decalcification was not associated with increased turnaround time. In multivariate analysis, consultation with other pathologists, use of immunohistochemistry, diagnosis of malignancy, and the number of slides studied continued to be significantly associated with prolonged turnaround time. Our findings suggest that diagnosis of malignancy is central to significantly prolonging the turnaround time for surgical pathology specimens, thus institutions that serve cancer centers will have longer turnaround time than those that do not. Copyright © 2012 Elsevier Inc. All rights reserved.

  12. Improvement of laboratory turnaround time using lean methodology.

    Science.gov (United States)

    Gupta, Shradha; Kapil, Sahil; Sharma, Monica

    2018-05-14

    Purpose The purpose of this paper is to discuss the implementation of lean methodology to reduce the turnaround time (TAT) of a clinical laboratory in a super speciality hospital. Delays in report delivery lead to delayed diagnosis increased waiting time and decreased customer satisfaction. The reduction in TAT will lead to increased patient satisfaction, quality of care, employee satisfaction and ultimately the hospital's revenue. Design/methodology/approach The generic causes resulting in increasing TAT of clinical laboratories were identified using lean tools and techniques such as value stream mapping (VSM), Gemba, Pareto Analysis and Root Cause Analysis. VSM was used as a tool to analyze the current state of the process and further VSM was used to design the future state with suggestions for process improvements. Findings This study identified 12 major non-value added factors for the hematology laboratory and 5 major non-value added factors for the biochemistry lab which were acting as bottlenecks resulting in limiting throughput. A four-month research study by the authors together with hospital quality department and laboratory staff members led to reduction of the average TAT from 180 to 95minutes in the hematology lab and from 268 to 208 minutes in the biochemistry lab. Practical implications Very few improvement initiatives in Indian healthcare are based on industrial engineering tools and techniques, which might be due to a lack of interaction between healthcare and engineering. The study provides a positive outcome in terms of improving the efficiency of services in hospitals and identifies a scope for lean in the Indian healthcare sector. Social implications Applying lean in the Indian healthcare sector gives its own potential solution to the problem caused, due to a wide gap between lean accessibility and lean implementation. Lean helped in changing the mindset of an organization toward providing the highest quality of services with faster delivery at

  13. Computer-aided detection system for chest radiography: reducing report turnaround times of examinations with abnormalities.

    Science.gov (United States)

    Kao, E-Fong; Liu, Gin-Chung; Lee, Lo-Yeh; Tsai, Huei-Yi; Jaw, Twei-Shiun

    2015-06-01

    The ability to give high priority to examinations with pathological findings could be very useful to radiologists with large work lists who wish to first evaluate the most critical studies. A computer-aided detection (CAD) system for identifying chest examinations with abnormalities has therefore been developed. To evaluate the effectiveness of a CAD system on report turnaround times of chest examinations with abnormalities. The CAD system was designed to automatically mark chest examinations with possible abnormalities in the work list of radiologists interpreting chest examinations. The system evaluation was performed in two phases: two radiologists interpreted the chest examinations without CAD in phase 1 and with CAD in phase 2. The time information recorded by the radiology information system was then used to calculate the turnaround times. All chest examinations were reviewed by two other radiologists and were divided into normal and abnormal groups. The turnaround times for the examinations with pathological findings with and without the CAD system assistance were compared. The sensitivity and specificity of the CAD for chest abnormalities were 0.790 and 0.697, respectively, and use of the CAD system decreased the turnaround time for chest examinations with abnormalities by 44%. The turnaround times required for radiologists to identify chest examinations with abnormalities could be reduced by using the CAD system. This system could be useful for radiologists with large work lists who wish to first evaluate the most critical studies. © The Foundation Acta Radiologica 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  14. A strategy for reducing turnaround time in design optimization using a distributed computer system

    Science.gov (United States)

    Young, Katherine C.; Padula, Sharon L.; Rogers, James L.

    1988-01-01

    There is a need to explore methods for reducing lengthly computer turnaround or clock time associated with engineering design problems. Different strategies can be employed to reduce this turnaround time. One strategy is to run validated analysis software on a network of existing smaller computers so that portions of the computation can be done in parallel. This paper focuses on the implementation of this method using two types of problems. The first type is a traditional structural design optimization problem, which is characterized by a simple data flow and a complicated analysis. The second type of problem uses an existing computer program designed to study multilevel optimization techniques. This problem is characterized by complicated data flow and a simple analysis. The paper shows that distributed computing can be a viable means for reducing computational turnaround time for engineering design problems that lend themselves to decomposition. Parallel computing can be accomplished with a minimal cost in terms of hardware and software.

  15. Benchmarking, benchmarks, or best practices? Applying quality improvement principles to decrease surgical turnaround time.

    Science.gov (United States)

    Mitchell, L

    1996-01-01

    The processes of benchmarking, benchmark data comparative analysis, and study of best practices are distinctly different. The study of best practices is explained with an example based on the Arthur Andersen & Co. 1992 "Study of Best Practices in Ambulatory Surgery". The results of a national best practices study in ambulatory surgery were used to provide our quality improvement team with the goal of improving the turnaround time between surgical cases. The team used a seven-step quality improvement problem-solving process to improve the surgical turnaround time. The national benchmark for turnaround times between surgical cases in 1992 was 13.5 minutes. The initial turnaround time at St. Joseph's Medical Center was 19.9 minutes. After the team implemented solutions, the time was reduced to an average of 16.3 minutes, an 18% improvement. Cost-benefit analysis showed a potential enhanced revenue of approximately $300,000, or a potential savings of $10,119. Applying quality improvement principles to benchmarking, benchmarks, or best practices can improve process performance. Understanding which form of benchmarking the institution wishes to embark on will help focus a team and use appropriate resources. Communicating with professional organizations that have experience in benchmarking will save time and money and help achieve the desired results.

  16. [Regional pilot study to evaluate the laboratory turnaround time according to the client source].

    Science.gov (United States)

    Salinas, M; López-Garrigós, M; Yago, M; Ortuño, M; Díaz, J; Marcaida, G; Chinchilla, V; Carratala, A; Aguado, C; Rodríguez-Borja, E; Laíz, B; Guaita, M; Esteban, A; Lorente, M A; Uris, J

    2011-01-01

    To show turnaround time to client source in eight laboratories covering eight Health Areas (2,014,475 inhabitants) of the Valencian Community (Spain). Internal Laboratory Information System (LIS) registers (test register and verification date and time), and daily LIS registers were used to design the indicators, These indicators showed the percentage of key tests requested (full blood count and serum glucose and thyrotropin) that were validated on the same day the blood was taken (inpatients and Primary Care and/or at 12 a.m. (inpatients). Urgent (stat) tests were also registered as key tests (serum troponin and potassium) and were recorded in minutes. Registers were collected and indicators calculated automatically through a Data Warehouse application and OLAP cube software. Long turnaround time differences were observed at 12 a.m. in inpatients, and in the day of sample extraction in primary care patients. The variability in turnaround of stat tests is related to hospital size, activity and validation by the laboratory physician. The study results show the large turnaround time disparity in eight Health Care Areas of Valencian Community. The various requesting sources covered by the laboratories create the need for continuous mapping processes redesign and benchmarking studies to achieve customer satisfaction. Copyright © 2010 SECA. Published by Elsevier Espana. All rights reserved.

  17. A blood-result turn-around time survey to improve congenital ...

    African Journals Online (AJOL)

    The results of a turn-around time study of blood specimens for syphilis serology in antenatal clinic attenders between 19 rural clinics and their base hospital, including a follow-up survey to assess the impact of interventions, are described. The objective of the study was to detennine how long blood samples took to get.

  18. Decreasing laboratory turnaround time and patient wait time by implementing process improvement methodologies in an outpatient oncology infusion unit.

    Science.gov (United States)

    Gjolaj, Lauren N; Gari, Gloria A; Olier-Pino, Angela I; Garcia, Juan D; Fernandez, Gustavo L

    2014-11-01

    Prolonged patient wait times in the outpatient oncology infusion unit indicated a need to streamline phlebotomy processes by using existing resources to decrease laboratory turnaround time and improve patient wait time. Using the DMAIC (define, measure, analyze, improve, control) method, a project to streamline phlebotomy processes within the outpatient oncology infusion unit in an academic Comprehensive Cancer Center known as the Comprehensive Treatment Unit (CTU) was completed. Laboratory turnaround time for patients who needed same-day lab and CTU services and wait time for all CTU patients was tracked for 9 weeks. During the pilot, the wait time from arrival to CTU to sitting in treatment area decreased by 17% for all patients treated in the CTU during the pilot. A total of 528 patients were seen at the CTU phlebotomy location, representing 16% of the total patients who received treatment in the CTU, with a mean turnaround time of 24 minutes compared with a baseline turnaround time of 51 minutes. Streamlining workflows and placing a phlebotomy station inside of the CTU decreased laboratory turnaround times by 53% for patients requiring same day lab and CTU services. The success of the pilot project prompted the team to make the station a permanent fixture. Copyright © 2014 by American Society of Clinical Oncology.

  19. Real time application of whole genome sequencing for outbreak investigation - What is an achievable turnaround time?

    Science.gov (United States)

    McGann, Patrick; Bunin, Jessica L; Snesrud, Erik; Singh, Seema; Maybank, Rosslyn; Ong, Ana C; Kwak, Yoon I; Seronello, Scott; Clifford, Robert J; Hinkle, Mary; Yamada, Stephen; Barnhill, Jason; Lesho, Emil

    2016-07-01

    Whole genome sequencing (WGS) is increasingly employed in clinical settings, though few assessments of turnaround times (TAT) have been performed in real-time. In this study, WGS was used to investigate an unfolding outbreak of vancomycin resistant Enterococcus faecium (VRE) among 3 patients in the ICU of a tertiary care hospital. Including overnight culturing, a TAT of just 48.5 h for a comprehensive report was achievable using an Illumina Miseq benchtop sequencer. WGS revealed that isolates from patient 2 and 3 differed from that of patient 1 by a single nucleotide polymorphism (SNP), indicating nosocomial transmission. However, the unparalleled resolution provided by WGS suggested that nosocomial transmission involved two separate events from patient 1 to patient 2 and 3, and not a linear transmission suspected by the time line. Rapid TAT's are achievable using WGS in the clinical setting and can provide an unprecedented level of resolution for outbreak investigations. Published by Elsevier Inc.

  20. Analysis of high-level radioactive slurries as a method to reduce DWPF turnaround times

    International Nuclear Information System (INIS)

    Coleman, C.J.; Bibler, N.E.; Ferrara, D.M.; Hay, M.S.

    1996-01-01

    Analysis of Defense Waste Processing Facility (DWPF) samples as slurries rather than as dried or vitrified samples is an effective way to reduce sample turnaround times. Slurries can be dissolved with a mixture of concentrated acids to yield solutions for elemental analysis by inductively coupled plasma-atomic emission spectroscopy (ICP-AES). Slurry analyses can be performed in eight hours, whereas analyses of vitrified samples require up to 40 hours to complete. Analyses of melter feed samples consisting of the DWPF borosilicate frit and either simulated or actual DWPF radioactive sludge were typically within a range of 3--5% of the predicted value based on the relative amounts of sludge and frit added to the slurry. The results indicate that the slurry analysis approach yields analytical accuracy and precision competitive with those obtained from analyses of vitrified samples. Slurry analyses offer a viable alternative to analyses of solid samples as a simple way to reduce analytical turnaround times

  1. Timeliness “at a glance”: assessing the turnaround time through the six sigma metrics.

    Science.gov (United States)

    Ialongo, Cristiano; Bernardini, Sergio

    2016-01-01

    Almost thirty years of systematic analysis have proven the turnaround time to be a fundamental dimension for the clinical laboratory. Several indicators are to date available to assess and report quality with respect to timeliness, but they sometimes lack the communicative immediacy and accuracy. The six sigma is a paradigm developed within the industrial domain for assessing quality and addressing goal and issues. The sigma level computed through the Z-score method is a simple and straightforward tool which delivers quality by a universal dimensionless scale and allows to handle non-normal data. Herein we report our preliminary experience in using the sigma level to assess the change in urgent (STAT) test turnaround time due to the implementation of total automation. We found that the Z-score method is a valuable and easy to use method for assessing and communicating the quality level of laboratory timeliness, providing a good correspondence with the actual change in efficiency which was retrospectively observed.

  2. Lean six sigma methodologies improve clinical laboratory efficiency and reduce turnaround times.

    Science.gov (United States)

    Inal, Tamer C; Goruroglu Ozturk, Ozlem; Kibar, Filiz; Cetiner, Salih; Matyar, Selcuk; Daglioglu, Gulcin; Yaman, Akgun

    2018-01-01

    Organizing work flow is a major task of laboratory management. Recently, clinical laboratories have started to adopt methodologies such as Lean Six Sigma and some successful implementations have been reported. This study used Lean Six Sigma to simplify the laboratory work process and decrease the turnaround time by eliminating non-value-adding steps. The five-stage Six Sigma system known as define, measure, analyze, improve, and control (DMAIC) is used to identify and solve problems. The laboratory turnaround time for individual tests, total delay time in the sample reception area, and percentage of steps involving risks of medical errors and biological hazards in the overall process are measured. The pre-analytical process in the reception area was improved by eliminating 3 h and 22.5 min of non-value-adding work. Turnaround time also improved for stat samples from 68 to 59 min after applying Lean. Steps prone to medical errors and posing potential biological hazards to receptionists were reduced from 30% to 3%. Successful implementation of Lean Six Sigma significantly improved all of the selected performance metrics. This quality-improvement methodology has the potential to significantly improve clinical laboratories. © 2017 Wiley Periodicals, Inc.

  3. Corporate Turnarounds in the High-tech Industry in UK

    OpenAIRE

    Xiao, Haixia

    2009-01-01

    Prior research on corporate turnaround relates to those organizations that have managed to move from poor performance to high performance within a relatively short time period by a case-study approach. The study also explores the role of leadership as a key factor in making turnaround successful as characterized by the change in CEO and in the board of directors. Finally, it explores the incentive systems of those firms during the turnaround. This study analyzed six public companies whic...

  4. Enquiry time as part of turnaround time: when do our clinicians really consult our results?

    Science.gov (United States)

    Rodríguez-Borja, Enrique; Villalba-Martínez, C; Carratalá-Calvo, A

    2014-07-01

    Traditionally, laboratories' turnaround times (TAT) have been calculated by only considering analytical or intralaboratory steps. The measure of the postanalytical impact in TAT has barely been studied and, more specifically, the running time from when finalised results are available to when clinicians make their first enquiry with an electronic medical record. During May-June of 2013, two 'Times' were collected from our laboratory information system for all the priority requests coming from our day hospitals: 'Validation time' (TV), as the request report time with full verified results and 'Enquiry time' (TQ), as the time when the first consult was made via electronic medical record. We classified requests in groups depending on time results, and TQ-TV (percentiles) were calculated for each group. 654 (69%) requests were consulted by clinicians before 15 : 00 on the same day with available results. 191 (20%) were consulted after 15 : 00 and had complete results as well (p50 (TQ-TV): 5 days) while 61 (7%) were never consulted (up to 31/12/2013). 39 (4%) requests were finally consulted before 15 : 00 h with no available results, but the average time difference between validation and enquiry was 31 min. The results obtained lead us to reconsider the TAT established with our day hospitals in order to know if priority has to be reviewed or if there are failures in follow-up results. 'Enquiry time' appears to be a powerful tool in detecting these issues and shows that TATs are no longer just a 'laboratory problem'. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  5. Building a new predictor for multiple linear regression technique-based corrective maintenance turnaround time.

    Science.gov (United States)

    Cruz, Antonio M; Barr, Cameron; Puñales-Pozo, Elsa

    2008-01-01

    This research's main goals were to build a predictor for a turnaround time (TAT) indicator for estimating its values and use a numerical clustering technique for finding possible causes of undesirable TAT values. The following stages were used: domain understanding, data characterisation and sample reduction and insight characterisation. Building the TAT indicator multiple linear regression predictor and clustering techniques were used for improving corrective maintenance task efficiency in a clinical engineering department (CED). The indicator being studied was turnaround time (TAT). Multiple linear regression was used for building a predictive TAT value model. The variables contributing to such model were clinical engineering department response time (CE(rt), 0.415 positive coefficient), stock service response time (Stock(rt), 0.734 positive coefficient), priority level (0.21 positive coefficient) and service time (0.06 positive coefficient). The regression process showed heavy reliance on Stock(rt), CE(rt) and priority, in that order. Clustering techniques revealed the main causes of high TAT values. This examination has provided a means for analysing current technical service quality and effectiveness. In doing so, it has demonstrated a process for identifying areas and methods of improvement and a model against which to analyse these methods' effectiveness.

  6. A point-of-care chemistry test for reduction of turnaround and clinical decision time.

    Science.gov (United States)

    Lee, Eui Jung; Shin, Sang Do; Song, Kyoung Jun; Kim, Seong Chun; Cho, Jin Seong; Lee, Seung Chul; Park, Ju Ok; Cha, Won Chul

    2011-06-01

    Our study compared clinical decision time between patients managed with a point-of-care chemistry test (POCT) and patients managed with the traditional central laboratory test (CLT). This was a randomized controlled multicenter trial in the emergency departments (EDs) of 5 academic teaching hospitals. We randomly assigned patients to POCT or CLT stratified by the Emergency Severity Index. A POCT chemistry analyzer (Piccolo; Abaxis, Inc, Union City, Calif), which is able to test liver panel, renal panel, pancreas enzymes, lipid panel, electrolytes, and blood gases, was set up in each ED. Primary and secondary end point was turnaround time and door-to-clinical-decision time. The total 2323 patients were randomly assigned to the POCT group (n = 1167) or to the CLT group (n = 1156). All of the basic characteristics were similar in the 2 groups. The turnaround time (median, interquartile range [IQR]) of the POCT group was shorter than that of the CLT group (14, 12-19 versus 55, 45-69 minutes; P CLT group (46, 33-61 versus 86, 68-107 minutes; P CLT group (P CLT. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. Decreasing Histology Turnaround Time Through Stepwise Innovation and Capacity Building in Rwanda

    Directory of Open Access Journals (Sweden)

    Gaspard Muvugabigwi

    2017-11-01

    Full Text Available Purpose: Minimal turnaround time for pathology results is crucial for highest-quality patient care in all settings, especially in low- and middle-income countries, where rural populations may have limited access to health care. Methods: We retrospectively determined the turnaround times (TATs for anatomic pathology specimens, comparing three different modes of operation that occurred throughout the development and implementation of our pathology laboratory at the Butaro Cancer Center of Excellence in Rwanda. Before opening this laboratory, TAT was measured in months because of inconsistent laboratory operations and a paucity of in-country pathologists. Results: We analyzed 2,514 individual patient samples across the three modes of study. Diagnostic mode 1 (samples sent out of the country for analysis had the highest median TAT, with an overall time of 30 days (interquartile range [IQR], 22 to 43 days. For diagnostic mode 2 (static image telepathology, the median TAT was 14 days (IQR, 7 to 27 days, and for diagnostic mode 3 (onsite expert diagnosis, it was 5 days (IQR, 2 to 9 days. Conclusion: Our results demonstrate that telepathology is a significant improvement over external expert review and can greatly assist sites in improving their TATs until pathologists are on site.

  8. Efficiency of performing pulmonary procedures in a shared endoscopy unit: procedure time, turnaround time, delays, and procedure waiting time.

    Science.gov (United States)

    Verma, Akash; Lee, Mui Yok; Wang, Chunhong; Hussein, Nurmalah B M; Selvi, Kalai; Tee, Augustine

    2014-04-01

    The purpose of this study was to assess the efficiency of performing pulmonary procedures in the endoscopy unit in a large teaching hospital. A prospective study from May 20 to July 19, 2013, was designed. The main outcome measures were procedure delays and their reasons, duration of procedural steps starting from patient's arrival to endoscopy unit, turnaround time, total case durations, and procedure wait time. A total of 65 procedures were observed. The most common procedure was BAL (61%) followed by TBLB (31%). Overall procedures for 35 (53.8%) of 65 patients were delayed by ≥ 30 minutes, 21/35 (60%) because of "spillover" of the gastrointestinal and surgical cases into the time block of pulmonary procedure. Time elapsed between end of pulmonary procedure and start of the next procedure was ≥ 30 minutes in 8/51 (16%) of cases. In 18/51 (35%) patients there was no next case in the room after completion of the pulmonary procedure. The average idle time of the room after the end of pulmonary procedure and start of next case or end of shift at 5:00 PM if no next case was 58 ± 53 minutes. In 17/51 (33%) patients the room's idle time was >60 minutes. A total of 52.3% of patients had the wait time >2 days and 11% had it ≥ 6 days, reason in 15/21 (71%) being unavailability of the slot. Most pulmonary procedures were delayed due to spillover of the gastrointestinal and surgical cases into the block time allocated to pulmonary procedures. The most common reason for difficulty encountered in scheduling the pulmonary procedure was slot unavailability. This caused increased procedure waiting time. The strategies to reduce procedure delays and turnaround times, along with improved scheduling methods, may have a favorable impact on the volume of procedures performed in the unit thereby optimizing the existing resources.

  9. National turnaround time survey: professional consensus standards for optimal performance and thresholds considered to compromise efficient and effective clinical management.

    Science.gov (United States)

    McKillop, Derek J; Auld, Peter

    2017-01-01

    Background Turnaround time can be defined as the time from receipt of a sample by the laboratory to the validation of the result. The Royal College of Pathologists recommends that a number of performance indicators for turnaround time should be agreed with stakeholders. The difficulty is in arriving at a goal which has some evidence base to support it other than what may simply be currently achievable technically. This survey sought to establish a professional consensus on the goals and meaning of targets for laboratory turnaround time. Methods A questionnaire was circulated by the National Audit Committee to 173 lead consultants for biochemistry in the UK. The survey asked each participant to state their current target turnaround time for core investigations in a broad group of clinical settings. Each participant was also asked to provide a professional opinion on what turnaround time would pose an unacceptable risk to patient safety for each departmental category. A super majority (2/3) was selected as the threshold for consensus. Results The overall response rate was 58% ( n = 100) with a range of 49-72% across the individual Association for Clinical Biochemistry and Laboratory Medicine regions. The consensus optimal turnaround time for the emergency department was 2 h considered unacceptable. The times for general practice and outpatient department were 48 h and for Wards 12 h, respectively. Conclusions We consider that the figures provide a useful benchmark of current opinion, but clearly more empirical standards will have to develop alongside other aspects of healthcare delivery.

  10. Identifying causes of laboratory turnaround time delay in the emergency department.

    Science.gov (United States)

    Jalili, Mohammad; Shalileh, Keivan; Mojtahed, Ali; Mojtahed, Mohammad; Moradi-Lakeh, Maziar

    2012-12-01

    Laboratory turnaround time (TAT) is an important determinant of patient stay and quality of care. Our objective is to evaluate laboratory TAT in our emergency department (ED) and to generate a simple model for identifying the primary causes for delay. We measured TATs of hemoglobin, potassium, and prothrombin time tests requested in the ED of a tertiary-care, metropolitan hospital during a consecutive one-week period. The time of different steps (physician order, nurse registration, blood-draw, specimen dispatch from the ED, specimen arrival at the laboratory, and result availability) in the test turnaround process were recorded and the intervals between these steps (order processing, specimen collection, ED waiting, transit, and within-laboratory time) and total TAT were calculated. Median TATs for hemoglobin and potassium were compared with those of the 1990 Q-Probes Study (25 min for hemoglobin and 36 min for potassium) and its recommended goals (45 min for 90% of tests). Intervals were compared according to the proportion of TAT they comprised. Median TATs (170 min for 132 hemoglobin tests, 225 min for 172 potassium tests, and 195.5 min for 128 prothrombin tests) were drastically longer than Q-Probes reported and recommended TATs. The longest intervals were ED waiting time and order processing.  Laboratory TAT varies among institutions, and data are sparse in developing countries. In our ED, actions to reduce ED waiting time and order processing are top priorities. We recommend utilization of this model by other institutions in settings with limited resources to identify their own priorities for reducing laboratory TAT.

  11. Reduction in laboratory turnaround time decreases emergency room length of stay

    Directory of Open Access Journals (Sweden)

    Kaushik N

    2018-04-01

    Full Text Available Nitin Kaushik,1 Victor S Khangulov,2 Matthew O’Hara,2 Ramy Arnaout3,4 1Becton, Dickinson and Company, Franklin Lakes, NJ, USA; 2Department of Health Economics and Outcomes Research, Boston Strategic Partners, Inc., Boston, MA, USA; 3Department of Pathology, 4Division of Biomedical Informatics, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA USA Objective: Laboratory tests are an important contributor to treatment decisions in the emergency department (ED. Rapid turnaround of laboratory tests can optimize ED throughout by reducing the length of stay (LOS and improving patient outcomes. Despite evidence supporting the effect of shorter turnaround time (TAT on LOS and outcomes, there is still a lack of large retrospective studies examining these associations. Here, we evaluated the effect of a reduction in laboratory TAT on ED LOS using retrospective analysis of Electronic Health Records (EHR. Materials and methods: Retrospective analysis of ED encounters from a large, US-based, de-identified EHR database and a separate analysis of ED encounters from the EHR of an ED at a top-tier tertiary care center were performed. Additionally, an efficiency model calculating the cumulative potential LOS time savings and resulting financial opportunity due to laboratory TAT reduction was created, assuming other factors affecting LOS are constant. Results: Multivariate regression analysis of patients from the multisite study showed that a 1-minute decrease in laboratory TAT was associated with 0.50 minutes of decrease in LOS. The single-site analysis confirmed our findings from the multisite analysis that a positive correlation between laboratory TAT and ED LOS exists in the ED population as a whole, as well as across different patient acuity levels. In addition, based on the calculations from the efficiency model, for a 5-, 10- and 15-minute TAT reduction, the single-site ED can potentially admit a total of 127, 256 and 386 additional

  12. A "Neurological Emergency Trolley" reduces turnaround time for high-risk medications in a general intensive care unit.

    Science.gov (United States)

    Ajzenberg, Henry; Newman, Paula; Harris, Gail-Anne; Cranston, Marnie; Boyd, J Gordon

    2018-02-01

    To reduce medication turnaround times during neurological emergencies, a multidisciplinary team developed a neurological emergency crash trolley in our intensive care unit. This trolley includes phenytoin, hypertonic saline and mannitol, as well as other equipment. The aim of this study was to assess whether the cart reduced turnaround times for these medications. In this retrospective cohort study, medication delivery times for two year epochs before and after its implementation were compared. Eligible patients were identified from our intensive care unit screening log. Adults who required emergent use of phenytoin, hypertonic saline or mannitol while in the intensive care unit were included. Groups were compared with nonparametric analyses. 33-bed general medical-surgical intensive care unit in an academic teaching hospital. Time to medication administration. In the pre-intervention group, there were 43 patients with 66 events. In the post-intervention group, there were 45 patients with 80 events. The median medication turnaround time was significantly reduced after implementation of the neurological emergency trolley (25 vs. 10minutes, p=0.003). There was no statistically significant difference in intensive care or 30-day survival between the two cohorts. The implementation of a novel neurological emergency crash trolley in our intensive care unit reduced medication turnaround times. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Turn-around improvements

    International Nuclear Information System (INIS)

    Redaelli, S.; Venturini Delsolaro, W.

    2012-01-01

    An efficient turn-around will be an important parameter for the integrated luminosity performance at LHC in 2012, when an operation with steady beam parameters and machine configuration will be achieved at the beginning of the run. Improvements of the operational cycle were already put successfully in place after the 2010 experience but additional ways to reduce the time required to setup collisions are possible. In this paper, the 2011 turn-around performance is reviewed and the benefits of the improvements from 2010 are presented. Phases of the operational cycle when further amelioration is possible are discussed and some proposal for a faster turn-around in 2012 are outlined. (authors)

  14. Customising turnaround time indicators to requesting clinician: a 10-year study through balanced scorecard indicators.

    Science.gov (United States)

    Salinas, Maria; López-Garrigós, Maite; Santo-Quiles, Ana; Gutierrez, Mercedes; Lugo, Javier; Lillo, Rosa; Leiva-Salinas, Carlos

    2014-09-01

    The purpose of this study is, first to present a 10-year monitoring of postanalytical turnaround time (TAT) adapted to different clinicians and patient situations, second to evaluate and analyse the indicators results during that period of time, and finally to show a synthetic appropriate indicator to be included in the balanced scorecard management system. TAT indicator for routine samples was devised as the percentage of certain key tests that were verified before a specific time on the phlebotomy day. A weighted mean synthetic indicator was also designed. They were calculated for inpatients at 15:00 and 12:00 and for primary care patients only at 15:00. The troponin TAT of emergency department patients, calculated as the difference between the troponin verification and registration time, was selected as the stat laboratory TAT indicator. The routine and stat TAT improved along the 10-year study period. The synthetic indicator showed the same trend. The implementation of systematic and continuous monitoring over years, promoted a continuous improvement in TAT which will probably benefit patient outcome and safety.

  15. Laboratory sample turnaround times: do they cause delays in the ED?

    Science.gov (United States)

    Gill, Dipender; Galvin, Sean; Ponsford, Mark; Bruce, David; Reicher, John; Preston, Laura; Bernard, Stephani; Lafferty, Jessica; Robertson, Andrew; Rose-Morris, Anna; Stoneham, Simon; Rieu, Romelie; Pooley, Sophie; Weetch, Alison; McCann, Lloyd

    2012-02-01

    Blood tests are requested for approximately 50% of patients attending the emergency department (ED). The time taken to obtain the results is perceived as a common reason for delay. The objective of this study was therefore to investigate the turnaround time (TAT) for blood results and whether this affects patient length of stay (LOS) and to identify potential areas for improvement. A time-in-motion study was performed at the ED of the John Radcliffe Hospital (JRH), Oxford, UK. The duration of each of the stages leading up to receipt of 101 biochemistry and haematology results was recorded, along with the corresponding patient's LOS. The findings reveal that the mean time for haematology results to become available was 1 hour 6 minutes (95% CI: 29 minutes to 2 hours 13 minutes), while biochemistry samples took 1 hour 42 minutes (95% CI: 1 hour 1 minute to 4 hours 21 minutes), with some positive correlation noted with the patient LOS, but no significant variation between different days or shifts. With the fastest 10% of samples being reported within 35 minutes (haematology) and 1 hour 5 minutes (biochemistry) of request, our study showed that delays can be attributable to laboratory TAT. Given the limited ability to further improve laboratory processes, the solutions to improving TAT need to come from a collaborative and integrated approach that includes strategies before samples reach the laboratory and downstream review of results. © 2010 Blackwell Publishing Ltd.

  16. Factors associated with long turnaround time for early infant diagnosis of HIV in Myanmar.

    Science.gov (United States)

    Thiha, Soe; Shewade, Hemant Deepak; Philip, Sairu; Aung, Thet Ko; Kyaw, Nang Thu Thu; Oo, Myo Minn; Kyaw, Khine Wut Yee; Wint War, May; Oo, Htun Nyunt

    2017-01-01

    A previous review of early infant diagnosis (EID) using polymerase chain reaction technology (PCR) under integrated HIV care (IHC) program in Myanmar revealed a low uptake of timely (within 6 to 8 weeks of babies' age) EID and a long turnaround time (TAT) of receiving results. This study aimed to determine the proportion and factors associated with the composite outcome of a long TAT (≥7 weeks; from sample collection to receipt of result by mother) or nonreceipt of result among HIV-exposed babies whose blood samples were collected for PCR at mother's CD4 count of 100-350 cells/mm 3 at enrollment [adjusted RR (0.95 confidence intervals, CI): 0.8 (0.7, 0.9)] had a 20% lower risk of long TAT or nonreceipt of results when compared with ≥350 cells/mm 3 . Distance between ART center and PCR facility ≥105 km [adjusted RR (0.95 CI): 1.2 (1.1, 1.4)], when compared with mother was high. Point-of-care testing for EID may reduce TAT/nonreceipt of results by the mother. Health system, laboratory, and logistic factors such as sample transportation, laboratory procedures, and result dispatching associated with long TAT should be further explored.

  17. Minimizing manual image segmentation turn-around time for neuronal reconstruction by embracing uncertainty.

    Directory of Open Access Journals (Sweden)

    Stephen M Plaza

    Full Text Available The ability to automatically segment an image into distinct regions is a critical aspect in many visual processing applications. Because inaccuracies often exist in automatic segmentation, manual segmentation is necessary in some application domains to correct mistakes, such as required in the reconstruction of neuronal processes from microscopic images. The goal of the automated segmentation tool is traditionally to produce the highest-quality segmentation, where quality is measured by the similarity to actual ground truth, so as to minimize the volume of manual correction necessary. Manual correction is generally orders-of-magnitude more time consuming than automated segmentation, often making handling large images intractable. Therefore, we propose a more relevant goal: minimizing the turn-around time of automated/manual segmentation while attaining a level of similarity with ground truth. It is not always necessary to inspect every aspect of an image to generate a useful segmentation. As such, we propose a strategy to guide manual segmentation to the most uncertain parts of segmentation. Our contributions include 1 a probabilistic measure that evaluates segmentation without ground truth and 2 a methodology that leverages these probabilistic measures to significantly reduce manual correction while maintaining segmentation quality.

  18. Efficiency of an automated reception and turnaround time management system for the phlebotomy room.

    Science.gov (United States)

    Yun, Soon Gyu; Shin, Jeong Won; Park, Eun Su; Bang, Hae In; Kang, Jung Gu

    2016-01-01

    Recent advances in laboratory information systems have largely been focused on automation. However, the phlebotomy services have not been completely automated. To address this issue, we introduced an automated reception and turnaround time (TAT) management system, for the first time in Korea, whereby the patient's information is transmitted directly to the actual phlebotomy site and the TAT for each phlebotomy step can be monitored at a glance. The GNT5 system (Energium Co., Ltd., Korea) was installed in June 2013. The automated reception and TAT management system has been in operation since February 2014. Integration of the automated reception machine with the GNT5 allowed for direct transmission of laboratory order information to the GNT5 without involving any manual reception step. We used the mean TAT from reception to actual phlebotomy as the parameter for evaluating the efficiency of our system. Mean TAT decreased from 5:45 min to 2:42 min after operationalization of the system. The mean number of patients in queue decreased from 2.9 to 1.0. Further, the number of cases taking more than five minutes from reception to phlebotomy, defined as the defect rate, decreased from 20.1% to 9.7%. The use of automated reception and TAT management system was associated with a decrease of overall TAT and an improved workflow at the phlebotomy room.

  19. Precise turnaround time measurement of laboratory processes using radiofrequency identification technology.

    Science.gov (United States)

    Mayer, Horst; Brümmer, Jens; Brinkmann, Thomas

    2011-01-01

    To implement Lean Six Sigma in our central laboratory we conducted a project to measure single pre-analytical steps influencing turnaround time (TAT) of emergency department (ED) serum samples. The traditional approach of extracting data from the Laboratory Information System (LIS) for a retrospective calculation of a mean TAT is not suitable. Therefore, we used radiofrequency identification (RFID) chips for real time tracking of individual samples at any pre-analytical step. 1,200 serum tubes were labelled with RFID chips and were provided to the emergency department. 3 RFID receivers were installed in the laboratory: at the outlet of the pneumatic tube system, at the centrifuge, and in the analyser area. In addition, time stamps of sample entry at the automated sample distributor and communication of results from the analyser were collected from LIS. 1,023 labelled serum tubes arrived at our laboratory. 899 RFID tags were used for TAT calculation. The following transfer times were determined (median 95th percentile in min:sec): pneumatic tube system --> centrifuge (01:25/04:48), centrifuge --> sample distributor (14:06/5:33), sample distributor --> analysis system zone (02:39/15:07), analysis system zone --> result communication (12:42/22:21). Total TAT was calculated at 33:19/57:40 min:sec. Manual processes around centrifugation were identified as a major part of TAT with 44%/60% (median/95th percentile). RFID is a robust, easy to use, and error-free technology and not susceptible to interferences in the laboratory environment. With this study design we were able to measure significant variations in a single manual sample transfer process. We showed that TAT is mainly influenced by manual steps around the centrifugation process and we concluded that centrifugation should be integrated in solutions for total laboratory automation.

  20. National survey on turnaround time of clinical biochemistry tests in 738 laboratories in China.

    Science.gov (United States)

    Zhang, Xiaoyan; Fei, Yang; Wang, Wei; Zhao, Haijian; Wang, Minqi; Chen, Bingquan; Zhou, Jie; Wang, Zhiguo

    2018-02-01

    This survey was initiated to estimate the current status of turnaround time (TAT) monitoring of clinical biochemistry in China, provide baseline data for establishment of quality specifications and analyze the impact factors of TAT. 738 laboratories were included. Questionnaires involved general information and data of related indicators of TAT during 1 week were provided to participating laboratories. Nine quality indicators were covered, which were medians, 90th and outlier rates of pre-examination, examination, and post-examination TAT. The 25th percentile, median, and 75th percentile of TATs were calculated as optimum, desirable, and minimum quality specifications. Percentages and sigma values were used to describe the outlier rates. Mann-Whitney and Kruskal-Wallis tests were used to identify the potential impacts of TAT. Response rate of this survey was 46.44%. More than 50% of the laboratories indicated they had set up target TATs in three time intervals and monitored TATs generally. The post-examination TAT of most laboratories was 0min, while the pre-examination and examination TAT varied. Sigma values of outlier rates for 45%~60% of laboratories were above 4, while 15%~20% of labs whose sigma values were below 3. Group comparisons suggested nurse or mechanical pipeline transportation, link laboratory information system with hospital information system, and using computer reporting instead of printing report were related to shorter TATs. Despite of the remarkable progresses of TATs in China, there was also room to improve. Laboratories should strengthen the construction of information systems, identify reasons for TAT delay to improve the service quality continuously. © 2017 Wiley Periodicals, Inc.

  1. Decreasing troponin turnaround time in the emergency department using the central laboratory: A process improvement study.

    Science.gov (United States)

    Boelstler, Arlene M; Rowland, Ralph; Theoret, Jennifer; Takla, Robert B; Szpunar, Susan; Patel, Shraddha P; Lowry, Andrew M; Pena, Margarita E

    2015-03-01

    To implement collaborative process improvement measures to reduce emergency department (ED) troponin turnaround time (TAT) to less than 60min using central laboratory. This was an observational, retrospective data study. A multidisciplinary team from the ED and laboratory identified opportunities and developed a new workflow model. Process changes were implemented in ED patient triage, staffing, lab collection and processing. Data collected included TAT of door-to-order, order-to-collect, collect-to-received, received-to-result, door-to-result, ED length of stay, and hemolysis rate before (January-August, 2011) and after (September 2011-June 2013) process improvement. After process improvement and implementation of the new workflow model, decreased median TAT (in min) was seen in door-to-order (54 [IQR43] vs. 11 [IQR20]), order-to-collect (15 [IQR 23] vs. 10 [IQR12]), collect-to-received (6 [IQR8] vs. 5 [IQR5]), received-to-result (30 [IQR12] vs. 24 [IQR11]), and overall door-to-result (117 [IQR60] vs. 60 [IQR40]). A troponin TAT of <60min was realized beginning in May 2012 (59 [IQR39]). Hemolysis rates decreased (14.63±0.74 vs. 3.36±1.99, p<0.0001), as did ED length of stay (5.87±2.73h vs. 5.15±2.34h, p<0.0001). Conclusion Troponin TAT of <60min using a central laboratory was achieved with collaboration between the ED and the laboratory; additional findings include a decreased ED length of stay. Copyright © 2014 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  2. Preparing printed circuit boards for rapid turn-around time on a protomat plotter

    International Nuclear Information System (INIS)

    Hawtree, J.

    1998-01-01

    This document describes the use of the LPKF ProtoMat mill/drill unit circuit board Plotter, with the associated CAD/CAM software BoardMaster and CircuitCAM. At present its primarily use here at Fermilab's Particle Physics Department is for rapid-turnover of prototype PCBs double-sided and single-sided copper clad printed circuit boards (PCBs). (The plotter is also capable of producing gravure films and engraving aluminum or plastic although we have not used it for this.) It has the capability of making traces 0.004 inch wide with 0.004 inch spacings which is appropriate for high density surface mount circuits as well as other through-mounted discrete and integrated components. One of the primary benefits of the plotter is the capability to produce double-sided drilled boards from CAD files in a few hours. However to achieve this rapid turn-around time, some care must be taken in preparing the files. This document describes how to optimize the process of PCB fabrication. With proper preparation, researchers can often have a completed circuit board in a day's time instead of a week or two wait with usual procedures. It is assumed that the software and hardware are properly installed and that the machinist is acquainted with the Win95 operating system and the basics of the associated software. This paper does not describe its use with pen plotters, lasers or rubouts. The process of creating a PCB (printed circuit board) begins with the CAD (computer-aided design) software, usually PCAD or VeriBest. These files are then moved to CAM (computer-aided machining) where they are edited and converted to put them into the proper format for running on the ProtoMat plotter. The plotter then performs the actual machining of the board. This document concentrates on the LPKF programs CircuitCam BASIS and BoardMaster for the CAM software. These programs run on a Windows 95 platform to run an LPKF ProtoMat 93s plotter

  3. Laboratory Tests Turnaround Time in Outpatient and Emergency Patients in Nigeria: Results of A Physician Survey on Point of Care Testing

    Directory of Open Access Journals (Sweden)

    Bolodeoku J

    2017-05-01

    Full Text Available Laboratory analytical turnaround time is a well-recognised indicator of how well a laboratory is performing and is sometimes regarded as the benchmark for laboratory performance. Methods: Total 104 doctors in public and private health institutions in Nigeria, spread across all six geo-political zones participated in survey requesting information on their experience with laboratory turnaround times in emergency situations (emergency room, special care baby unit, intensive care unit, dialysis unit and outpatient situations (general medicine and diabetes. Results: The average turnaround time in hours was 5.12, 8.35, 7.32 and 8.33 for the emergency room, special care baby unit, intensive care unit and dialysis unit, respectively. For the outpatient situations, the average turnaround time in hours was 10.74 and 15.70 hours for the diabetes and general medical outpatients. The median range (hours and modal range (hours for: the emergency room was 2-4 and <2; the special care baby unit was 4-8 and 4-8; the intensive care unit was 2-4 and 2-4; the dialysis unit was 4-8 and 4-8. The median range (hours and modal range (hours for: the general outpatient clinic was 12-24 and 12-24; the diabetic clinic was 4-8 and 12-24 hours. Conclusion: These turnaround time results are quite consistent with published data from other countries. However, there is some measure of improvement that is required in some areas to reduce the laboratory turnaround in the emergency situations. This could be overcome with the introduction of more point of care testing devices into emergency units.

  4. Ditching the Disc: The Effects of Cloud-Based Image Sharing on Department Efficiency and Report Turnaround Times in Mammography.

    Science.gov (United States)

    Morgan, Matthew B; Young, Elizabeth; Harada, Scott; Winkler, Nicole; Riegert, Joanna; Jones, Tony; Hu, Nan; Stein, Matthew

    2017-12-01

    In screening mammography, accessing prior examination images is crucial for accurate diagnosis and avoiding false-positives. When women visit multiple institutions for their screens, these "outside" examinations must be retrieved for comparison. Traditionally, prior images are obtained by faxing requests to other institutions and waiting for standard mail (film or CD-ROM), which can greatly delay report turnaround times. Recently, advancements in cloud-based image transfer technology have opened up more efficient options for examination transfer between institutions. The objective of this study was to evaluate the effect of cloud-based image transfer on mammography department workflow, time required to obtain prior images, and report turnaround times. Sixty screening examinations requiring prior images were placed into two groups (30 each). The control group used the standard institutional protocol for requesting prior images: faxing requests and waiting for mailed examinations. The experimental group used a cloud-based transfer for both requesting and receiving examinations. The mean number of days between examination request and examination receipt was measured for both groups and compared. The mean number of days from examination request to receipt was 6.08 days (SD 3.50) in the control group compared with 3.16 days (SD 3.95) in the experimental group. Using a cloud-based image transfer to obtain prior mammograms resulted in an average reduction of 2.92 days (P = .0361; 95% confidence interval 0.20-5.65) between examination request and receipt. This improvement in system efficiency is relevant for interpreting radiologists working to improve reporting times and for patients anxious to receive their mammography results. Copyright © 2017 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  5. The Impact of a Health IT Changeover on Medical Imaging Department Work Processes and Turnaround Times: A mixed method study.

    Science.gov (United States)

    Georgiou, A; Prgomet, M; Lymer, S; Hordern, A; Ridley, L; Westbrook, J

    2015-01-01

    To assess the impact of introducing a new Picture Archiving and Communication System (PACS) and Radiology Information System (RIS) on: (i) Medical Imaging work processes; and (ii) turnaround times (TATs) for x-ray and CT scan orders initiated in the Emergency Department (ED). We employed a mixed method study design comprising: (i) semi-structured interviews with Medical Imaging Department staff; and (ii) retrospectively extracted ED data before (March/April 2010) and after (March/April 2011 and 2012) the introduction of a new PACS/RIS. TATs were calculated as: processing TAT (median time from image ordering to examination) and reporting TAT (median time from examination to final report). Reporting TAT for x-rays decreased significantly after introduction of the new PACS/RIS; from a median of 76 hours to 38 hours per order (pMedical Imaging staff reported that the changeover to the new PACS/RIS led to gains in efficiency, particularly regarding the accessibility of images and patient-related information. Nevertheless, assimilation of the new PACS/RIS with existing Departmental work processes was considered inadequate and in some instances unsafe. Issues highlighted related to the synchronization of work tasks (e.g., porter arrangements) and the material set up of the work place (e.g., the number and location of computers). The introduction of new health IT can be a "double-edged sword" providing improved efficiency but at the same time introducing potential hazards affecting the effectiveness of the Medical Imaging Department.

  6. Analytic turnaround time study for integrated reporting of pathology results on electronic medical records using the Illuminate system

    Directory of Open Access Journals (Sweden)

    Tawfik O

    2016-09-01

    Full Text Available Timely pathology results are critical for appropriate diagnosis and management of patients. Yet workflows in laboratories remain ad hoc and involve accessing multiple systems with no direct linkage between patient history and prior or pending pathology records for the case being analyzed. A major hindrance in timely reporting of pathology results is the need to incorporate/interface with multiple electronic health records (EHRs. We evaluated the Illuminate PatientView software (Illuminate integration into pathologist's workflow. Illuminate is a search engine architecture that has a repository of textual information from many hospital systems. Our goal was to develop a comprehensive, user friendly patient summary display to integrate the current fractionated subspecialty specific systems. An analytical time study noting changes in turnaround time (TAT before and after Illuminate implementation was recorded for reviewers, including pathologists, residents and fellows. Reviewers' TAT for 359 cases was recorded (200 cases before and 159 after implementation. The impact of implementing Illuminate on transcriptionists’ workflow was also studied. Average TAT to retrieve EHRs prior to Illuminate was 5:32 min (range 1:35-10:50. That time was significantly reduced to 35 seconds (range 10 sec-1:10 min using Illuminate. Reviewers were very pleased with the ease in accessing information and in eliminating the draft paper documents of the pathology reports, eliminating up to 65 min/day (25-65 min by transcriptionists matching requisition with paperwork. Utilizing Illuminate improved workflow, decreased TAT and minimized cost. Patient care can be improved through a comprehensive patient management system that facilitates communications between isolated information systems.

  7. Prepopulated radiology report templates: a prospective analysis of error rate and turnaround time.

    Science.gov (United States)

    Hawkins, C M; Hall, S; Hardin, J; Salisbury, S; Towbin, A J

    2012-08-01

    Current speech recognition software allows exam-specific standard reports to be prepopulated into the dictation field based on the radiology information system procedure code. While it is thought that prepopulating reports can decrease the time required to dictate a study and the overall number of errors in the final report, this hypothesis has not been studied in a clinical setting. A prospective study was performed. During the first week, radiologists dictated all studies using prepopulated standard reports. During the second week, all studies were dictated after prepopulated reports had been disabled. Final radiology reports were evaluated for 11 different types of errors. Each error within a report was classified individually. The median time required to dictate an exam was compared between the 2 weeks. There were 12,387 reports dictated during the study, of which, 1,173 randomly distributed reports were analyzed for errors. There was no difference in the number of errors per report between the 2 weeks; however, radiologists overwhelmingly preferred using a standard report both weeks. Grammatical errors were by far the most common error type, followed by missense errors and errors of omission. There was no significant difference in the median dictation time when comparing studies performed each week. The use of prepopulated reports does not alone affect the error rate or dictation time of radiology reports. While it is a useful feature for radiologists, it must be coupled with other strategies in order to decrease errors.

  8. Real-time polymerase chain reaction with melting analysis of positive blood culture specimens in bloodstream infections: diagnostic value and turnaround time.

    Science.gov (United States)

    Angeletti, Silvia; Gherardi, Giovanni; De Florio, Lucia; Avola, Alessandra; Crea, Francesca; Riva, Elisabetta; Vitali, Massimiliano Andrea; Galluzzo, Sara; Dicuonzo, Giordano

    2013-01-01

    A Real-time polymerase chain reaction (PCR) with melting analysis was devised to target bacterial and fungal genes together with the most prevalent antimicrobial resistance genes in 250 positive blood culture broths. This method allowed the blood culture cultivated pathogens to be classified into clinically relevant groups such as Enterobacteriaceae, oxidase-positive bacilli, oxidase-positive coccobacilli, S. aureus and yeast. Enterococci and streptococci could be distinguished from CoNS only by the Gram stain. Gram-positive bacilli were discriminated from Gram-positive cocci by Gram stain. Furthermore, the most important antimicrobial resistant genes such as mecA, vanA, bla TEM , bla SHV and bla CTX-M could be identified. All results were obtained with a turnaround time of three hours from the moment of blood culture positivity compared to 24-72 hours for phenotypic methods. In conclusion, the proposed approach can allow the clinician to implement proper early management of sepsis patients.

  9. External Quality Assessment of stat test intralaboratory turnaround times. Pilot study from the Members of the Working Group for the Standardization and Promotion of Turnaround Time Control under the Auspices of the Comitato Italiano per la Standardizzazione dei Metodi Ematologici e di Laboratorio.

    Science.gov (United States)

    Negri, M; Carraro, P; Caenaro, G; Cappelletti, P; Giavarina, D; Mezzena, G; Prandini, B; Rampoldi, E; Siviero, F

    1998-11-01

    We describe procedures, results and prospects of a pilot program in External Quality Assessment (EQA) of the stat test intralaboratory turnaround times. Our goals are to promote quality by systematic monitoring and comparison of performances by laboratories, continuous investigation into the state of the art of the processes from receipt of sample to transmission of results and creation of a data base for standardization of measures and definition of consensus values for turnaround time. Of 30 laboratories invited to participate, 25 took part, agreeing to record times of arrival and transmission for all determinations of three analytes (blood hemoglobin, serum/plasma potassium and plasma prothrombin time) for seven consecutive days and to continue for one or more further periods of seven days as necessary if there were less than 300 determinations for each analyte. Within a preset time limit, data were sent by e-mail on an Excel file and we sent back two reports per analyte, showing: i) the graph for time vs. percentage of tests completed and several measures of turnaround time; ii) results of all laboratories in graph form, allowing each laboratory to identify only its own data. The high proportion of participating laboratories among those invited (83%) encourages us to implement the EQA program systematically, on a half-yearly basis, extending it to all laboratories wishing to participate in Italy or elsewhere in Europe.

  10. Short recovery time NMR probe

    International Nuclear Information System (INIS)

    Ramia, M.E.; Martin, C.A.; Jeandrevin, S.

    2011-01-01

    A NMR probe for low frequency and short recovery time is presented in this work. The probe contains the tuning circuit, diode expanders and quarter wavelength networks to protect the receiver from both the amplifier noise and the coil ringing following the transmitter power pulse. It also possesses a coil damper which is activated by of non active components. The probe performance shows a recovery time of about of 15μs a sensitive Q factor reduction and an increase of the signal to noise ratio of about 68% during the reception at a work frequency of 2 MHz. (author)

  11. Use of mobile phones and text messaging to decrease the turnaround time for early infant HIV diagnosis and notification in rural Zambia: an observational study.

    Science.gov (United States)

    Sutcliffe, Catherine G; Thuma, Philip E; van Dijk, Janneke H; Sinywimaanzi, Kathy; Mweetwa, Sydney; Hamahuwa, Mutinta; Moss, William J

    2017-03-08

    Early infant diagnosis of HIV infection is challenging in rural sub-Saharan Africa as blood samples are sent to central laboratories for HIV DNA testing, leading to delays in diagnosis and treatment initiation. Simple technologies to rapidly deliver results to clinics and notify mothers of test results would decrease many of these delays. The feasibility of using mobile phones to contact mothers was evaluated. In addition, the first two years of implementation of a national short message service (SMS) reporting system to deliver test results from the laboratory to the clinic were evaluated. The study was conducted in Macha, Zambia from 2013 to 2015 among mothers of HIV-exposed infants. Mothers were interviewed about mobile phone use and willingness to be contacted directly or through their rural health center. Mothers were contacted according to their preferred method of communication when test results were available. Mothers of positive infants were asked to return to the clinic as soon as possible. Dates of sample collection, delivery of test results to the clinic and notification of mothers were documented in addition to test results. Four hundred nineteen mothers and infants were enrolled. Only 30% of mothers had ever used a mobile phone. 96% of mobile phone owners were reached by study staff and 98% of mothers without mobile phones were contacted through their rural health center. Turnaround times for mothers of positive infants were approximately 2 weeks shorter than for mothers of negative infants. Delivery of test results by the national SMS system improved from 2013 to 2014, with increases in the availability of texted results (38 vs. 91%) and arrival of the texted result prior to the hardcopy report (27 vs. 83%). Texted results arriving at the clinic before the hardcopy were received a median of 19 days earlier. Four discrepancies between texted and hardcopy results were identified out of 340 tests. Mobile phone and text messaging technology has the

  12. Identification of Blood Culture Isolates Directly from Positive Blood Cultures by Use of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry and a Commercial Extraction System: Analysis of Performance, Cost, and Turnaround Time

    OpenAIRE

    Lagacé-Wiens, Philippe R. S.; Adam, Heather J.; Karlowsky, James A.; Nichol, Kimberly A.; Pang, Paulette F.; Guenther, Jodi; Webb, Amanda A.; Miller, Crystal; Alfa, Michelle J.

    2012-01-01

    Matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) mass spectrometry represents a revolution in the rapid identification of bacterial and fungal pathogens in the clinical microbiology laboratory. Recently, MALDI-TOF has been applied directly to positive blood culture bottles for the rapid identification of pathogens, leading to reductions in turnaround time and potentially beneficial patient impacts. The development of a commercially available extraction kit (Bruker Sepsit...

  13. Phase II of a Six sigma Initiative to Study DWPF SME Analytical Turnaround Times: SRNL's Evaluation of Carbonate-Based Dissolution Methods

    International Nuclear Information System (INIS)

    Edwards, Thomas

    2005-01-01

    The Analytical Development Section (ADS) and the Statistical Consulting Section (SCS) of the Savannah River National Laboratory (SRNL) are participating in a Six Sigma initiative to improve the Defense Waste Processing Facility (DWPF) Laboratory. The Six Sigma initiative has focused on reducing the analytical turnaround time of samples from the Slurry Mix Evaporator (SME) by developing streamlined sampling and analytical methods [1]. The objective of Phase I was to evaluate the sub-sampling of a larger sample bottle and the performance of a cesium carbonate (Cs 2 CO 3 ) digestion method. Successful implementation of the Cs 2 CO 3 fusion method in the DWPF would have important time savings and convenience benefits because this single digestion would replace the dual digestion scheme now used. A single digestion scheme would result in more efficient operations in both the DWPF shielded cells and the inductively coupled plasma--atomic emission spectroscopy (ICP-AES) laboratory. By taking a small aliquot of SME slurry from a large sample bottle and dissolving the vitrified SME sample with carbonate fusion methods, an analytical turnaround time reduction from 27 hours to 9 hours could be realized in the DWPF. This analytical scheme has the potential for not only dramatically reducing turnaround times, but also streamlining operations to minimize wear and tear on critical shielded cell components that are prone to fail, including the Hydragard(trademark) sampling valves and manipulators. Favorable results from the Phase I tests [2] led to the recommendation for a Phase II effort as outlined in the DWPF Technical Task Request (TTR) [3]. There were three major tasks outlined in the TTR, and SRNL issued a Task Technical and QA Plan [4] with a corresponding set of three major task activities: (1) Compare weight percent (wt%) total solids measurements of large volume samples versus peanut vial samples. (2) Evaluate Cs 2 CO 3 and K 2 CO 3 fusion methods using DWPF simulated

  14. Comparison of turnaround time and total cost of HIV testing before and after implementation of the 2014 CDC/APHL Laboratory Testing Algorithm for diagnosis of HIV infection.

    Science.gov (United States)

    Chen, Derrick J; Yao, Joseph D

    2017-06-01

    Updated recommendations for HIV diagnostic laboratory testing published by the Centers for Disease Control and Prevention and the Association of Public Health Laboratories incorporate 4th generation HIV immunoassays, which are capable of identifying HIV infection prior to seroconversion. The purpose of this study was to compare turnaround time and cost between 3rd and 4th generation HIV immunoassay-based testing algorithms for initially reactive results. The clinical microbiology laboratory database at Mayo Clinic, Rochester, MN was queried for 3rd generation (from November 2012 to May 2014) and 4th generation (from May 2014 to November 2015) HIV immunoassay results. All results from downstream supplemental testing were recorded. Turnaround time (defined as the time of initial sample receipt in the laboratory to the time the final supplemental test in the algorithm was resulted) and cost (based on 2016 Medicare reimbursement rates) were assessed. A total of 76,454 and 78,998 initial tests were performed during the study period using the 3rd generation and 4th generation HIV immunoassays, respectively. There were 516 (0.7%) and 581 (0.7%) total initially reactive results, respectively. Of these, 304 (58.9%) and 457 (78.7%) were positive by supplemental testing. There were 10 (0.01%) cases of acute HIV infection identified with the 4th generation algorithm. The most frequent tests performed to confirm an HIV-positive case using the 3rd generation algorithm, which were reactive initial immunoassay and positive HIV-1 Western blot, took a median time of 1.1 days to complete at a cost of $45.00. In contrast, the most frequent tests performed to confirm an HIV-positive case using the 4th generation algorithm, which included a reactive initial immunoassay and positive HIV-1/-2 antibody differentiation immunoassay for HIV-1, took a median time of 0.4 days and cost $63.25. Overall median turnaround time was 2.2 and 1.5 days, and overall median cost was $63.90 and $72.50 for

  15. Identification of blood culture isolates directly from positive blood cultures by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and a commercial extraction system: analysis of performance, cost, and turnaround time.

    Science.gov (United States)

    Lagacé-Wiens, Philippe R S; Adam, Heather J; Karlowsky, James A; Nichol, Kimberly A; Pang, Paulette F; Guenther, Jodi; Webb, Amanda A; Miller, Crystal; Alfa, Michelle J

    2012-10-01

    Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry represents a revolution in the rapid identification of bacterial and fungal pathogens in the clinical microbiology laboratory. Recently, MALDI-TOF has been applied directly to positive blood culture bottles for the rapid identification of pathogens, leading to reductions in turnaround time and potentially beneficial patient impacts. The development of a commercially available extraction kit (Bruker Sepsityper) for use with the Bruker MALDI BioTyper has facilitated the processing required for identification of pathogens directly from positive from blood cultures. We report the results of an evaluation of the accuracy, cost, and turnaround time of this method for 61 positive monomicrobial and 2 polymicrobial cultures representing 26 species. The Bruker MALDI BioTyper with the Sepsityper gave a valid (score, >1.7) identification for 85.2% of positive blood cultures with no misidentifications. The mean reduction in turnaround time to identification was 34.3 h (P MALDI-TOF was used for all blood cultures and 26.5 h in a more practical setting where conventional identification or identification from subcultures was required for isolates that could not be directly identified by MALDI-TOF. Implementation of a MALDI-TOF-based identification system for direct identification of pathogens from blood cultures is expected to be associated with a marginal increase in operating costs for most laboratories. However, the use of MALDI-TOF for direct identification is accurate and should result in reduced turnaround time to identification.

  16. Hospital turnaround strategies.

    Science.gov (United States)

    Langabeer, James

    2008-01-01

    Despite reports of higher profitability in recent years, hospitals are failing at a faster rate than ever before. Although many hospitals leave decisions regarding revenues and costs to chief financial officers and their staff, this is a recipe for disaster. From research conducted over the last 4 years on hospital bankruptcies and turnarounds, the author found that a common series of actions will help organizations evade collapse. The author explored these turnaround strategies through research and analysis of a variety of hospitals and health systems that had a high probability of immediate financial crisis or collapse. His continued observation and analysis of these hospitals in subsequent years showed that most hospitals never emerge from their bleak financial conditions. However, a few hospital administrations have successfully turned around their organizations.

  17. Testing ΛCDM cosmology at turnaround: where to look for violations of the bound?

    International Nuclear Information System (INIS)

    Tanoglidis, D.; Pavlidou, V.; Tomaras, T.N.

    2015-01-01

    In ΛCDM cosmology, structure formation is halted shortly after dark energy dominates the mass/energy budget of the Universe. A manifestation of this effect is that in such a cosmology the turnaround radius—the non-expanding mass shell furthest away from the center of a structure— has an upper bound. Recently, a new, local, test for the existence of dark energy in the form of a cosmological constant was proposed based on this turnaround bound. Before designing an experiment that, through high-precision determination of masses and —independently— turnaround radii, will challenge ΛCDM cosmology, we have to answer two important questions: first, when turnaround-scale structures are predicted to be close enough to their maximum size, so that a possible violation of the bound may be observable. Second, which is the best mass scale to target for possible violations of the bound. These are the questions we address in the present work. Using the Press-Schechter formalism, we find that turnaround structures have in practice already stopped forming, and consequently, the turnaround radius of structures must be very close to the maximum value today. We also find that the mass scale of ∼ 10 13  M ⊙ characterizes the turnaround structures that start to form in a statistically important number density today —and even at an infinite time in the future, since structure formation has almost stopped. This mass scale also separates turnaround structures with qualitatively different cosmological evolution: smaller structures are no longer readjusting their mass distribution inside the turnaround scale, they asymptotically approach their ultimate abundance from higher values, and they are common enough to have, at some epoch, experienced major mergers with structures of comparable mass; larger structures exhibit the opposite behavior. We call this mass scale the transitional mass scale and we argue that it is the optimal for the purpose outlined above. As a corollary

  18. Measuring trade-offs that matter: assessing the impact of a new electronic cross-match policy on the turnaround time and the cross-match workload efficiency.

    Science.gov (United States)

    Lin, David M; Goldfinger, Dennis; Lu, Qun; Wallace, Bridget; Kosaka-Nguyen, Dawn; Wood, Alisa; Porter, Bethany; Bumerts, Pamela; Jeffery, Rebecca; Fang, Amy; Stalcup, Irene; Penaflorida, Tracy; Ziman, Alyssa

    2014-12-01

    Our traditional cross-match (XM) policy generated a significant number of XM units that were never issued. To minimize the unnecessary XM workload, we proposed a new policy where orders eligible for the electronic XM (EXM) are pended until orders to issue red blood cells (RBCs) are received. To address concerns that this new policy might unduly delay blood availability, we conducted a study to assess whether the new policy was noninferior to the traditional policy with regard to the turnaround time (TAT). We monitored the TAT and XM workload efficiency (XM-to-issue [C : I] ratio) for a total of 8 weeks split between the two policies' periods. The primary outcome was the proportion of RBC issue requests that was turned around in less than 12 minutes. Fifty percent (1133 of 2265) of issue requests were turned around in 12 minutes or less under the traditional policy compared to 43.9% (975 of 2223) under the new policy (absolute difference of 6.1%; 95% confidence interval [CI], 3.2%-9.1%; p trade-off between delays in the TAT and efficiency gains in the XM workload remained acceptable for patient care. © 2014 AABB.

  19. Laboratory-based clinical audit as a tool for continual improvement: an example from CSF chemistry turnaround time audit in a South-African teaching hospital.

    Science.gov (United States)

    Imoh, Lucius C; Mutale, Mubanga; Parker, Christopher T; Erasmus, Rajiv T; Zemlin, Annalise E

    2016-01-01

    Timeliness of laboratory results is crucial to patient care and outcome. Monitoring turnaround times (TAT), especially for emergency tests, is important to measure the effectiveness and efficiency of laboratory services. Laboratory-based clinical audits reveal opportunities for improving quality. Our aim was to identify the most critical steps causing a high TAT for cerebrospinal fluid (CSF) chemistry analysis in our laboratory. A 6-month retrospective audit was performed. The duration of each operational phase across the laboratory work flow was examined. A process-mapping audit trail of 60 randomly selected requests with a high TAT was conducted and reasons for high TAT were tested for significance. A total of 1505 CSF chemistry requests were analysed. Transport of samples to the laboratory was primarily responsible for the high average TAT (median TAT = 170 minutes). Labelling accounted for most delays within the laboratory (median TAT = 71 minutes) with most delays occurring after regular work hours (P audit identified sample transportation, work shift periods and use of inappropriate CSF sample tubes as drivers of high TAT for CSF chemistry in our laboratory. The results of this audit will be used to change pre-analytical practices in our laboratory with the aim of improving TAT and customer satisfaction.

  20. National survey on intra-laboratory turnaround time for some most common routine and stat laboratory analyses in 479 laboratories in China.

    Science.gov (United States)

    Fei, Yang; Zeng, Rong; Wang, Wei; He, Falin; Zhong, Kun; Wang, Zhiguo

    2015-01-01

    To investigate the state of the art of intra-laboratory turnaround time (intra-TAT), provide suggestions and find out whether laboratories accredited by International Organization for Standardization (ISO) 15189 or College of American Pathologists (CAP) will show better performance on intra-TAT than non-accredited ones. 479 Chinese clinical laboratories participating in the external quality assessment programs of chemistry, blood gas, and haematology tests organized by the National Centre for Clinical Laboratories in China were included in our study. General information and the median of intra-TAT of routine and stat tests in last one week were asked in the questionnaires. The response rate of clinical biochemistry, blood gas, and haematology testing were 36% (479/1307), 38% (228/598), and 36% (449/1250), respectively. More than 50% of laboratories indicated that they had set up intra-TAT median goals and almost 60% of laboratories declared they had monitored intra-TAT generally for every analyte they performed. Among all analytes we investigated, the intra-TAT of haematology analytes was shorter than biochemistry while the intra-TAT of blood gas analytes was the shortest. There were significant differences between median intra-TAT on different days of the week for routine tests. However, there were no significant differences in median intra-TAT reported by accredited laboratories and non-accredited laboratories. Many laboratories in China are aware of intra-TAT control and are making effort to reach the target. There is still space for improvement. Accredited laboratories have better status on intra-TAT monitoring and target setting than the non-accredited, but there are no significant differences in median intra-TAT reported by them.

  1. Implementation of a new 'community' laboratory CD4 service in a rural health district in South Africa extends laboratory services and substantially improves local reporting turnaround time.

    Science.gov (United States)

    Coetzee, L M; Cassim, N; Glencross, D K

    2015-12-16

    The CD4 integrated service delivery model (ITSDM) provides for reasonable access to pathology services across South Africa (SA) by offering three new service tiers that extend services into remote, under-serviced areas. ITSDM identified Pixley ka Seme as such an under-serviced district. To address the poor service delivery in this area, a new ITSDM community (tier 3) laboratory was established in De Aar, SA. Laboratory performance and turnaround time (TAT) were monitored post implementation to assess the impact on local service delivery. Using the National Health Laboratory Service Corporate Data Warehouse, CD4 data were extracted for the period April 2012-July 2013 (n=11,964). Total mean TAT (in hours) was calculated and pre-analytical and analytical components assessed. Ongoing testing volumes, as well as external quality assessment performance across ten trials, were used to indicate post-implementation success. Data were analysed using Stata 12. Prior to the implementation of CD4 testing at De Aar, the total mean TAT was 20.5 hours. This fell to 8.2 hours post implementation, predominantly as a result of a lower pre-analytical mean TAT reducing from a mean of 18.9 to 1.8 hours. The analytical testing TAT remained unchanged after implementation and monthly test volumes increased by up to 20%. External quality assessment indicated adequate performance. Although subjective, questionnaires sent to facilities reported improved service delivery. Establishing CD4 testing in a remote community laboratory substantially reduces overall TAT. Additional community CD4 laboratories should be established in under-serviced areas, especially where laboratory infrastructure is already in place.

  2. Improved sensitivity, safety and laboratory turnaround time in the diagnosis of pulmonary tuberculosis by use of bleach sedimentation

    Directory of Open Access Journals (Sweden)

    Ameh James

    2015-11-01

    Full Text Available Background: Inadequate diagnostic processes and human resources in laboratories contribute to a high burden of tuberculosis (TB in low- and middle-income countries. Direct smear microscopy is relied on for TB diagnosis; however, sensitivity rates vary. To improve sensitivity of direct microscopy, the researchers employed several approaches, including sputum digestion and concentration of acid-fast bacilli (AFB, a technique which uses commercial bleach. Objectives: This study compared methods used to diagnose active Mycobacterium tuberculosis infections. Methods: Three sputum specimens were collected from each of 340 participants in Abuja, Nigeria, over two consecutive days. Direct microscopy was performed on all specimens; following microscopy, one specimen from each patient was selected randomly for bleach sedimentation and one for Lowenstein-Jensen culture. Results: Direct microscopy produced 28.8% AFB-positive results, whilst bleach sedimentation resulted in 30.3%. When compared with the cultures, 26.5% were AFB true positive using direct microscopy and 27.1% using bleach sedimentation. Whilst the specificity rate between these two methods was not statistically significant (P = 0.548, the sensitivity rate was significant (P = 0.004. Conclusion: Based on these results, bleach increases the sensitivity of microscopy compared with direct smear and has similar specificity. When diagnosing new cases of pulmonary TB, one bleach-digested smear is as sensitive as three direct smears, reducing waiting times for patients and ensuring the safety of laboratory technicians.

  3. FCC-hh turn-around cycle

    CERN Document Server

    Alemany Fernandez, Reyes; Bartmann, Wolfgang; Buffat, Xavier; Niemi, Arto; Schulte, Daniel; Solfaroli Camillocci, Matteo; Stoel, Linda

    2016-01-01

    The turn-around cycle time of a collider is defined as the time spent between the end of stable beams and the start of the next stable beams period, and its calculation is of fundamental importance. On one side it is a crucial ingredient for the computation of the optimal time spent in luminosity production, which defines the integrated luminosity per fill or store. On the other side, combined with the availability and reliability of the machine, it allows to perform a detailed breakdown of the operational performance of the collider over an operational season, i.e. percentage of time in stable beams and beam in the machine with respect to down time. This paper presents a preliminary operational cycle definition for the hadron-hadron Future Circular Collider, as a base line for estimating the corresponding turn-around time. The cycle definition is based on the Large Hadron Collider (LHC) operational cycle. Two turn-around times are presented, the theoretical one and a more realistic one based on the LHC exper...

  4. TURNAROUND COORDINATOR. YES OR NOT?

    Directory of Open Access Journals (Sweden)

    Martin HROMÁDKA

    2013-12-01

    Full Text Available Both low cost carriers ‘fresh wind’ and liberalisation of ground handling market makes airlines to be cost-wise in every single field. Thus, ground handling contract are cutting down in terms of their costs. Handling companies struggle with pressure being put from the market environment, they rush 25 minutes turnaround with couple of people. This can be potentially dangerous from the safety point of view. One of possible solutions seems to be introducing turnaround coordinator, person who would supervise the ramp handling procedures. This paper discusses the role of turnaround coordinator within the aircraft turnaround process. Duties and responsibilities of this person are described. However, not every airport is staffing this position. The survey shows that smaller airports pay much more attention to this issue than the big ones.

  5. Reducing turnaround time for laboratory test results does not improve retention of stable HIV-infected adults on POV program: experience from Uganda.

    Science.gov (United States)

    Maselle, Edna; Muhanguzi, Asaph; Muhumuza, Simon; Nansubuga, Jeniffer; Nawavvu, Cecilia; Namusobya, Jeniffer; Kamya, Moses R; Semitala, Fred C

    2014-01-01

    HIV/ AIDS clinics in resource limited settings (RLS) face increasing numbers of patients and workforce shortage [1, 2]. To address these challenges, efficient models of care like pharmacy only visits (POV) and nurse only visits (NOV) are recommended [3]. The Makerere University Joint AIDS Program (MJAP), a PEPFAR funded program providing care to over 42,000 HIV infected adults has implemented the POV model since 2009. In this model, stable patients on antiretroviral therapy (ART) with adherence to ART >95% and Karnofsky score >90% are reviewed by a doctor every four months but visit pharmacy for ART re-fills every two months. A study conducted in August 2011 showed low retention on the POV program with symptomatic diseases, pending CD4 count, complete blood count results, and poor adherence to ART as the major reasons for the non-retention in the POV program. To improve retention on POV, the TAT (Turnaround Time) for laboratory results (the main reason for non-retention in the previous study) was reduced from one month to one week. In August 2012, the study was repeated to assess the effect of reducing TAT on improving retention one year after patients were placed on POV. A cohort analysis of data from patients in August 2011 and in August 2012 on POV was done. We compared retention of POV before and after reducing the TAT for laboratory results. Retention on POV was 12.0% (95% CI 9.50-14.7) among 619 patients in 2011, (70% Females), mean age was 33 years, Standard Deviation (SD) 8.5 compared to 11.1% (95% CI 9.15-13.4) among 888 patients (70% Females), mean age 38.3 years, SD 8.9 in 2012 (p=0.59). The main reasons for non-retention on the POV program in 2012 were poor adherence to ART (23%) and missed clinic appointments (14%). Reducing TAT for laboratory test results did not improve retention of stable HIV-infected adults on POV in our clinic. Strategies for improving adherence to ART and keeping clinic appointments need to be employed to balance workload and

  6. Transient nanobubbles in short-time electrolysis

    NARCIS (Netherlands)

    Svetovoy, Vitaly; Sanders, Remco G.P.; Elwenspoek, Michael Curt

    2013-01-01

    Water electrolysis in a microsystem is observed and analyzed on a short-time scale of ∼10 μs. The very unusual properties of the process are stressed. An extremely high current density is observed because the process is not limited by the diffusion of electroactive species. The high current is

  7. High mortality in HIV-infected children diagnosed in hospital underscores need for faster diagnostic turnaround time in prevention of mother-to-child transmission of HIV (PMTCT) programs.

    Science.gov (United States)

    Wagner, Anjuli; Slyker, Jennifer; Langat, Agnes; Inwani, Irene; Adhiambo, Judith; Benki-Nugent, Sarah; Tapia, Ken; Njuguna, Irene; Wamalwa, Dalton; John-Stewart, Grace

    2015-02-15

    Despite expanded programs for prevention of mother-to-child HIV transmission (PMTCT), HIV-infected infants may not be diagnosed until they are ill. Comparing HIV prevalence and outcomes in infants diagnosed in PMTCT programs to those in hospital settings may improve pediatric HIV diagnosis strategies. HIV-exposed infants turnaround time for tests were compared between PMTCT programs and hospital sites. Among the enrolled cohort, baseline characteristics, survival, and timing of antiretroviral therapy (ART) initiation were compared between infants diagnosed in PMTCT programs versus hospital. Among 1,923 HIV-exposed infants, HIV prevalence was higher among infants tested in hospital than PMTCT early infant diagnosis (EID) sites (41% vs. 11%, p 3 times as likely to die (HR = 3.1, 95% CI = 1.3-7.6). Among HIV-exposed infants, hospital-based testing was more likely to detect an HIV-infected infant than PMTCT testing. Because young symptomatic infants diagnosed with HIV during hospitalization have very high mortality, every effort should be made to diagnose HIV infections before symptom onset. Systems to expedite turnaround time at PMTCT EID sites and to routinize inpatient pediatric HIV testing are necessary to improve pediatric HIV outcomes.

  8. Making Sense of School Turnarounds

    Science.gov (United States)

    Hess, Frederick M.

    2012-01-01

    Today, in a sector flooded with $3.5 billion in School Improvement Grant funds and the resulting improvement plans, there's great faith that "turnaround" strategies are a promising way to tackle stubborn problems with persistently low-performing schools. Unlike traditional reform efforts, with their emphasis on incremental improvement, turnarounds…

  9. Maximizing value for planned maintenance and turnarounds

    Energy Technology Data Exchange (ETDEWEB)

    Crager, John [Asset Performance Canada, ULC (Canada)

    2011-07-01

    In this presentation, Asset Performance Canada elaborates on turnaround management, and provides insight into managing strategies and risks associated with turnaround processes. Value is created fast as turnarounds progress from the strategy and scope definition phases towards the planning and execution phases. Turnarounds employ best practice solutions through common processes proven effective by data, research, and experience, ensuring consistent value creation, performance tracking, and shared lesson-learning. Adherence to the turnaround work process by carefully selected planning team members with clearly defined responsibilities and expectations, as well as an effective process for scope collection and management, are crucial to turnaround success. Further to this, a formal risk management process, employing automated risk tracking software and a safety management plan for assessing risks and their severity is also invaluable in avoiding any additional costs and schedule delays. Finally, assessment of team readiness and alignment through use of the turnaround readiness index, and rapid management of discovery work, can aid in contingency management.

  10. Short time ahead wind power production forecast

    International Nuclear Information System (INIS)

    Sapronova, Alla; Meissner, Catherine; Mana, Matteo

    2016-01-01

    An accurate prediction of wind power output is crucial for efficient coordination of cooperative energy production from different sources. Long-time ahead prediction (from 6 to 24 hours) of wind power for onshore parks can be achieved by using a coupled model that would bridge the mesoscale weather prediction data and computational fluid dynamics. When a forecast for shorter time horizon (less than one hour ahead) is anticipated, an accuracy of a predictive model that utilizes hourly weather data is decreasing. That is because the higher frequency fluctuations of the wind speed are lost when data is averaged over an hour. Since the wind speed can vary up to 50% in magnitude over a period of 5 minutes, the higher frequency variations of wind speed and direction have to be taken into account for an accurate short-term ahead energy production forecast. In this work a new model for wind power production forecast 5- to 30-minutes ahead is presented. The model is based on machine learning techniques and categorization approach and using the historical park production time series and hourly numerical weather forecast. (paper)

  11. Short time ahead wind power production forecast

    Science.gov (United States)

    Sapronova, Alla; Meissner, Catherine; Mana, Matteo

    2016-09-01

    An accurate prediction of wind power output is crucial for efficient coordination of cooperative energy production from different sources. Long-time ahead prediction (from 6 to 24 hours) of wind power for onshore parks can be achieved by using a coupled model that would bridge the mesoscale weather prediction data and computational fluid dynamics. When a forecast for shorter time horizon (less than one hour ahead) is anticipated, an accuracy of a predictive model that utilizes hourly weather data is decreasing. That is because the higher frequency fluctuations of the wind speed are lost when data is averaged over an hour. Since the wind speed can vary up to 50% in magnitude over a period of 5 minutes, the higher frequency variations of wind speed and direction have to be taken into account for an accurate short-term ahead energy production forecast. In this work a new model for wind power production forecast 5- to 30-minutes ahead is presented. The model is based on machine learning techniques and categorization approach and using the historical park production time series and hourly numerical weather forecast.

  12. Nuclear graphite ageing and turnaround

    International Nuclear Information System (INIS)

    Marsden, B.J.; Hall, G.N.; Smart, J.

    2001-01-01

    Graphite moderated reactors are being operated in many countries including, the UK, Russia, Lithuania, Ukraine and Japan. Many of these reactors will operate well into the next century. New designs of High Temperature Graphite Moderated Reactors (HTRS) are being built in China and Japan. The design life of these graphite-moderated reactors is governed by the ageing of the graphite core due to fast neutron damage, and also, in the case of carbon dioxide cooled reactors by the rate of oxidation of the graphite. Nuclear graphites are polycrystalline in nature and it is the irradiation-induced damage to the individual graphite crystals that determines the material property changes with age. The life of a graphite component in a nuclear reactor can be related to the graphite irradiation induced dimensional changes. Graphites typically shrink with age, until a point is reached where the shrinkage stops and the graphite starts to swell. This change from shrinkage to swelling is known as ''turnaround''. It is well known that pre-oxidising graphite specimens caused ''turnaround'' to be delayed, thus extending the life of the graphite, and hence the life of the reactor. However, there was no satisfactory explanation of this behaviour. This paper presents a numerical crystal based model of dimensional change in graphite, which explains the delay in ''turnaround'' in the pre-oxidised specimens irradiated in a fast neutron flux, in terms of crystal accommodation and orientation and change in compliance due to radiolytic oxidation. (author)

  13. Are anomalously short tunnelling times measurable?

    International Nuclear Information System (INIS)

    Delgado, V.; Muga, J.G.

    1996-01-01

    Low and Mende have analyzed the conditions that would make possible an actual measurement of an anomalously short traversal time through a potential barrier concluding that such a measurement cannot be made because it is not possible to describe the tunnelling of a wave packet initially close to the barrier by the open-quote open-quote usual wave packet space time analysis close-quote close-quote. We complement this work in several ways: It is argued that the described failure of the usual formalism occurs under a set of too restrictive conditions, some of them not physically motivated, so it does not necessarily imply the impossibility of such a measurement. However, by retaining only conditions well motivated on physical grounds we have performed a systematic numerical check which shows that the conclusion by Low and Mende is indeed generally valid. It is shown that, as speculated by Low and Mende, the process is dominated by over the barrier transmission. Copyright copyright 1996 Academic Press, Inc

  14. Combining Quick-Turnaround and Batch Workloads at Scale

    Science.gov (United States)

    Matthews, Gregory A.

    2012-01-01

    NAS uses PBS Professional to schedule and manage the workload on Pleiades, an 11,000+ node 1B cluster. At this scale the user experience for quick-turnaround jobs can degrade, which led NAS initially to set up two separate PBS servers, each dedicated to a particular workload. Recently we have employed PBS hooks and scheduler modifications to merge these workloads together under one PBS server, delivering sub-1-minute start times for the quick-turnaround workload, and enabling dynamic management of the resources set aside for that workload.

  15. Challenge energy policy turnaround; Herausforderung Energiewende

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Michael; Brandt-Schwabedissen, Annette; Graaff, Rudolf; Queitsch, Peter; Thomas, Roland [Staedte- und Gemeindebund Nordrhein-Westfalen e.V., Duesseldorf (Germany); Becker, Sven [Trianel GmbH, Aachen (Germany); Portz, Norbert; Schmitz, Johannes [Deutscher Staedte- und Gemeindebund, Berlin (Germany)

    2011-07-01

    The documentation under consideration makes suggestions to cities and communities in light of the energy policy turnaround. The documentation contains the following contributions: (1) Power generation by means of renewable energy resources (Johannes Schmitz); (2) The energy policy turnaround needs acceptance - communication as the key to success (Sven Becker); (3) Climate-conscious communal construction planning (Michael Becker); (4) Establishment of climate concepts (Peter Queitsch); (5) Energetic measures at buildings (Annette Brandt-Schwabedissen); (6) Energy political turnaround and awarding (Norbert Portz); (7) Electromobility (Roland Thomas); (8) Position paper of DStB for the energy policy turnaround.

  16. From turnaround to continuous innovation

    DEFF Research Database (Denmark)

    Bjarnø, Ole-Christian

    2002-01-01

    In this article a five year longitudinal study performed at a medium-sized producer of electronics is reported during which we studied the company's change process. The paper deals with the concept of strategic sourcing as a component in turnaround change management. Based on theories of strategic...... sourcing, explorative case research and continuous innovation a series of findings is identified, and from these findings a management model is proposed. This model is intended to fill in an identified gap in the toolbox for maintenance and further development of the business partners network established...

  17. Peru turnaround tied to privatization

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    Petroleos del Peru predicts a 10% increase in Peru's oil production this year and a further increase in 1994. Petroperu also forecasts a sharp increase in drilling in Peru this year. After several years of declining oil production, a gradual turnaround in the cash strapped country's petroleum industry is largely tied to its progress in privatization. The government last year began a campaign to privatize all state owned companies by the end of July 1995. The paper discusses forecasts by Petroperu; the contract of Occidental del Amazonas Inc.; the Petromar privatization; Great Western's contract; development of the Aguaytia gas field; and refinery contracts

  18. Summary inside IBM's historic turnaround

    CERN Document Server

    2014-01-01

    This work offers a summary of the book "WHO SAYS ELEPHANTS CAN'T DANCE? Inside IBM's Historic Turnaround" by Louis Gerstner.In nine years as the chairman and CEO of International Business Machine Corporation (IBM), Louis Gerstner brought about a dramatic change in the company's fortunes. When he took charge, IBM was on the verge of extinction as the victim of rapid changes in the computer industry. However, instead of breaking up IBM as most analysts were suggesting, Gerstner and his management team turned the company around and restored it to a position of power and influence within the indu

  19. Series Overview. Sustaining School Turnaround at Scale. Brief 1

    Science.gov (United States)

    Education Resource Strategies, 2012

    2012-01-01

    Members of the non-profit organization Education Resource Strategies (ERS) have worked for over a decade with leaders of urban school systems to help them organize talent, time and technology to support great schools at scale. One year into the Federal program they are noticing significant differences in district turnaround approaches, engagement…

  20. Progress Report 2013. Turnaround Arts Initiative

    Science.gov (United States)

    Stoelinga, Sara Ray; Joyce, Katie; Silk, Yael

    2013-01-01

    This interim progress report provides a look at Turnaround Arts schools in their first year, including: (1) a summary of the evaluation design and research questions; (2) a preliminary description of strategies used to introduce the arts in Turnaround Arts schools; and (3) a summary of school reform indicators and student achievement data at…

  1. Design spectra development considering short time histories

    International Nuclear Information System (INIS)

    Weiner, E.O.

    1983-01-01

    Two separate programs, MODQKE and MDOF, were written to provide a capability of obtaining equipment spectra from design spectra. MODQKE generates or modifies acceleration histories to conform with design spectra pertaining to, say, a foundation. MDOF is a simple linear modal superposition program that solves for equipment support histories using the design spectra conforming histories as input. Equipment spectra, then, are obtained from the support histories using MODQKE. MODQKE was written to modify or provide new histories with special attention paid to short seismic records. A technique from the open literature was borrowed to generate an initial history that approximates a given response spectrum. Further refinement is done with smoothing cycles in which several correction signals are added to the history in a way that produces a least squares fit between actual and prescribed spectra. Provision is made for history shaping, a baseline correction, and final scaling. MODQKE performance has been demonstrated with seven examples having zero to ten percent damping ratios, and 2.5 seconds to 20 seconds durations and a variety of target spectra. The examples show the program is inexpensive to use. MDOF is a simple modal superposition program. It has no eigensolver, and the user supplies mode shapes, frequencies, and participation factors as input. Floor spectra can be generated from design spectra by using a history from MODQKE that conforms to the design spectrum as input to MDOF. Floor motions from MDOF can be fed back to MODQKE without modification to obtain the floor spectra. A simple example is given to show how equipment mass effects can be incorporated into the MDOF solution. Any transient solution capability can be used to replace MDOF. For example, a direct transient approach may be desirable if both the equipment and floor structures are to be included in the model with different damping fractions. (orig./HP)

  2. Kālacakra: Shortlies Considerations on Time

    Directory of Open Access Journals (Sweden)

    Adrián Muñoz

    2013-05-01

    Full Text Available This paper calls for a comparative reading of both the Buddhist conception of time and a branch of Western phenomenology. With special emphasis on the Madhyamaka Buddhist school, it discusses the way in which fugacity and impermanence are similarly discussed by French philosopher Gaston Bachelard in his L’intuition de l’instant. In both cases, the stress lies on the fact that duration is but a mental construct lacking true, absolute reality, while at the same time the human being is subjected to hopes of transcendence which, in turn, engender disillusion and delusion.

  3. Inferring interdependencies from short time series

    Indian Academy of Sciences (India)

    Abstract. Complex networks provide an invaluable framework for the study of interlinked dynamical systems. In many cases, such networks are constructed from observed time series by first estimating the ...... does not quantify causal relations (unlike IOTA, or .... Africa_map_regions.svg, which is under public domain.

  4. Phonemes as short time cognitive components

    DEFF Research Database (Denmark)

    Feng, Ling; Hansen, Lars Kai

    2006-01-01

    are the smallest contrastive unit in the sound system of a language. Generalizable components were found deriving from phonemes based on homomorphic filtering features with basic time scale (20 msec). We sparsified the features based on energy as a preprocessing means to eliminate the intrinsic noise. Independent...

  5. Potential barrier classification by short-time measurement

    International Nuclear Information System (INIS)

    Granot, Er'el; Marchewka, Avi

    2006-01-01

    We investigate the short-time dynamics of a delta-function potential barrier on an initially confined wave packet. There are mainly two conclusions: (A) At short times the probability density of the first particles that passed through the barrier is unaffected by it. (B) When the barrier is absorptive (i.e., its potential is imaginary) it affects the transmitted wave function at shorter times than a real potential barrier. Therefore, it is possible to distinguish between an imaginary and a real potential barrier by measuring its effect at short times only on the transmitting wave function

  6. Potential barrier classification by short-time measurement

    Science.gov (United States)

    Granot, Er'El; Marchewka, Avi

    2006-03-01

    We investigate the short-time dynamics of a delta-function potential barrier on an initially confined wave packet. There are mainly two conclusions: (A) At short times the probability density of the first particles that passed through the barrier is unaffected by it. (B) When the barrier is absorptive (i.e., its potential is imaginary) it affects the transmitted wave function at shorter times than a real potential barrier. Therefore, it is possible to distinguish between an imaginary and a real potential barrier by measuring its effect at short times only on the transmitting wave function.

  7. Decreasing Turnaround Time and Increasing Patient Satisfaction in a Safety Net Hospital-Based Pediatrics Clinic Using Lean Six Sigma Methodologies.

    Science.gov (United States)

    Jayasinha, Yasangi

    2016-01-01

    Increasingly, health care quality indicators are focusing on patient-centeredness as an indicator of performance. The National Quality Forum lists assessment of patient experience, often conducted using patient surveys, as a top priority. We developed a patient-reported time stamp data collection tool that was used to collect cycle times in a safety net hospital-based outpatient pediatrics clinic. Data were collected using patient-reported survey to obtain cycle times in Pediatric clinic, as well as qualitative and quantitative patient satisfaction data. Several rapid-cycle improvements were performed using Lean Six Sigma methodologies to reduce cycle time by eliminating waste and revise unnecessary processes to improve operational effectiveness and patient and staff satisfaction. A total of 94 surveys were collected and revealed average cycle time of 113 minutes. Our measured patient satisfaction rating was 87%. Discharge and check-in processes were identified as the least efficient and were targeted for intervention. Following implementation, the overall cycle time was decreased from 113 to 90 minutes. Patient satisfaction ratings increased from 87% to 95%. We demonstrate that using Lean Six Sigma tools can be invaluable to clinical restructuring and redesign and results in measurable, improved outcomes in care delivery.

  8. Evaluation of a centrifuge with rapid turnaround time for the preparation of plasma samples for measurement of common STAT markers on the ACS: 180 system.

    Science.gov (United States)

    Foster, K; Datta, P; Orswell, M; Tasaico, K; Alpert, A; Bluestein, B

    2000-01-01

    Reported is the evaluation of a new centrifugation method, Statspin, that addresses both time and sample separation integrity. The method can successfully separate the plasma fraction from the cellular material in 2 minutes as compared to 20 minutes for the conventional centrifuge method. The Statspin, combined with the ACS:180 system, can generate test results in less than 30 minutes, exclusive of transport to the laboratory. This study demonstrated that the combined technologies offer timing-saving improvements for clinical laboratories offering STAT immunoassays for cardiac markers, endocrine molecules, and therapeutic drugs.

  9. Improving Music Genre Classification by Short-Time Feature Integration

    DEFF Research Database (Denmark)

    Meng, Anders; Ahrendt, Peter; Larsen, Jan

    2005-01-01

    Many different short-time features, using time windows in the size of 10-30 ms, have been proposed for music segmentation, retrieval and genre classification. However, often the available time frame of the music to make the actual decision or comparison (the decision time horizon) is in the range...... of seconds instead of milliseconds. The problem of making new features on the larger time scale from the short-time features (feature integration) has only received little attention. This paper investigates different methods for feature integration and late information fusion for music genre classification...

  10. Short-time quantum propagator and Bohmian trajectories

    Science.gov (United States)

    de Gosson, Maurice; Hiley, Basil

    2013-12-01

    We begin by giving correct expressions for the short-time action following the work Makri-Miller. We use these estimates to derive an accurate expression modulo Δt2 for the quantum propagator and we show that the quantum potential is negligible modulo Δt2 for a point source, thus justifying an unfortunately largely ignored observation of Holland made twenty years ago. We finally prove that this implies that the quantum motion is classical for very short times.

  11. Short-time quantum propagator and Bohmian trajectories

    International Nuclear Information System (INIS)

    Gosson, Maurice de; Hiley, Basil

    2013-01-01

    We begin by giving correct expressions for the short-time action following the work Makri–Miller. We use these estimates to derive an accurate expression modulo Δt 2 for the quantum propagator and we show that the quantum potential is negligible modulo Δt 2 for a point source, thus justifying an unfortunately largely ignored observation of Holland made twenty years ago. We finally prove that this implies that the quantum motion is classical for very short times.

  12. Journal peer review: a bar or bridge? An analysis of a paper's revision history and turnaround time, and the effect on citation.

    Science.gov (United States)

    Rigby, J; Cox, D; Julian, K

    2018-01-01

    Journal peer review lies at the heart of academic quality control. This article explores the journal peer review process and seeks to examine how the reviewing process might itself contribute to papers, leading them to be more highly cited and to achieve greater recognition. Our work builds on previous observations and views expressed in the literature about (a) the role of actors involved in the research and publication process that suggest that peer review is inherent in the research process and (b) on the contribution reviewers themselves might make to the content and increased citation of papers. Using data from the journal peer review process of a single journal in the Social Sciences field (Business, Management and Accounting), we examine the effects of peer review on papers submitted to that journal including the effect upon citation, a novel step in the study of the outcome of peer review. Our detailed analysis suggests, contrary to initial assumptions, that it is not the time taken to revise papers but the actual number of revisions that leads to greater recognition for papers in terms of citation impact. Our study provides evidence, albeit limited to the case of a single journal, that the peer review process may constitute a form of knowledge production and is not the simple correction of errors contained in submitted papers.

  13. Short-time quantum dynamics of sharp boundaries potentials

    Energy Technology Data Exchange (ETDEWEB)

    Granot, Er' el, E-mail: erel@ariel.ac.il; Marchewka, Avi

    2015-02-15

    Despite the high prevalence of singular potential in general, and rectangular potentials in particular, in applied scattering models, to date little is known about their short time effects. The reason is that singular potentials cause a mixture of complicated local as well as non-local effects. The object of this work is to derive a generic method to calculate analytically the short-time impact of any singular potential. In this paper it is shown that the scattering of a smooth wavefunction on a singular potential is totally equivalent, in the short-time regime, to the free propagation of a singular wavefunction. However, the latter problem was totally addressed analytically in Ref. [7]. Therefore, this equivalency can be utilized in solving analytically the short time dynamics of any smooth wavefunction at the presence of a singular potentials. In particular, with this method the short-time dynamics of any problem where a sharp boundaries potential (e.g., a rectangular barrier) is turned on instantaneously can easily be solved analytically.

  14. Short-time quantum dynamics of sharp boundaries potentials

    Science.gov (United States)

    Granot, Er'el; Marchewka, Avi

    2015-02-01

    Despite the high prevalence of singular potential in general, and rectangular potentials in particular, in applied scattering models, to date little is known about their short time effects. The reason is that singular potentials cause a mixture of complicated local as well as non-local effects. The object of this work is to derive a generic method to calculate analytically the short-time impact of any singular potential. In this paper it is shown that the scattering of a smooth wavefunction on a singular potential is totally equivalent, in the short-time regime, to the free propagation of a singular wavefunction. However, the latter problem was totally addressed analytically in Ref. [7]. Therefore, this equivalency can be utilized in solving analytically the short time dynamics of any smooth wavefunction at the presence of a singular potentials. In particular, with this method the short-time dynamics of any problem where a sharp boundaries potential (e.g., a rectangular barrier) is turned on instantaneously can easily be solved analytically.

  15. Short-time quantum dynamics of sharp boundaries potentials

    International Nuclear Information System (INIS)

    Granot, Er'el; Marchewka, Avi

    2015-01-01

    Despite the high prevalence of singular potential in general, and rectangular potentials in particular, in applied scattering models, to date little is known about their short time effects. The reason is that singular potentials cause a mixture of complicated local as well as non-local effects. The object of this work is to derive a generic method to calculate analytically the short-time impact of any singular potential. In this paper it is shown that the scattering of a smooth wavefunction on a singular potential is totally equivalent, in the short-time regime, to the free propagation of a singular wavefunction. However, the latter problem was totally addressed analytically in Ref. [7]. Therefore, this equivalency can be utilized in solving analytically the short time dynamics of any smooth wavefunction at the presence of a singular potentials. In particular, with this method the short-time dynamics of any problem where a sharp boundaries potential (e.g., a rectangular barrier) is turned on instantaneously can easily be solved analytically

  16. Quality of Standard Reference Materials for Short Time Activation Analysis

    International Nuclear Information System (INIS)

    Ismail, S.S.; Oberleitner, W.

    2003-01-01

    Some environmental reference materials (CFA-1633 b, IAEA-SL-1, SARM-1,BCR-176, Coal-1635, IAEA-SL-3, BCR-146, and SRAM-5) were analysed by short-time activation analysis. The results show that these materials can be classified in three groups, according to their activities after irradiation. The obtained results were compared in order to create a quality index for determination of short-lived nuclides at high count rates. It was found that Cfta is not a suitable standard for determining very short-lived nuclides (half-lives<1 min) because the activity it produces is 15-fold higher than that SL-3. Biological reference materials, such as SRM-1571, SRM-1573, SRM-1575, SRM-1577, IAEA-392, and IAEA-393, were also investigated by a higher counting efficiency system. The quality of this system and its well-type detector for investigating short-lived nuclides was discussed

  17. Short-time quantum propagator and Bohmian trajectories

    Energy Technology Data Exchange (ETDEWEB)

    Gosson, Maurice de, E-mail: maurice.degosson@gmail.com [Universität Wien, Fakultät für Mathematik, NuHAG, Wien 1090 (Austria); Hiley, Basil [University of London, Birkbeck College, Theoretical Physics Unit, London WC1E 7HX (United Kingdom)

    2013-12-06

    We begin by giving correct expressions for the short-time action following the work Makri–Miller. We use these estimates to derive an accurate expression modulo Δt{sup 2} for the quantum propagator and we show that the quantum potential is negligible modulo Δt{sup 2} for a point source, thus justifying an unfortunately largely ignored observation of Holland made twenty years ago. We finally prove that this implies that the quantum motion is classical for very short times.

  18. A short history of fractal-Cantorian space-time

    International Nuclear Information System (INIS)

    Marek-Crnjac, L.

    2009-01-01

    The article attempts to give a short historical overview of the discovery of fractal-Cantorian space-time starting from the 17th century up to the present. In the last 25 years a great number of scientists worked on fractal space-time notably Garnet Ord in Canada, Laurent Nottale in France and Mohamed El Naschie in England who gave an exact mathematical procedure for the derivation of the dimensionality and curvature of fractal space-time fuzzy manifold.

  19. Turnarounds to Transfer: Design beyond the Modes

    Science.gov (United States)

    Eddy, Jennifer

    2014-01-01

    In "Turnarounds to Transfer," teachers design a collection of tasks toward the summative performance goal but go beyond the Communicative mode criteria: they must assess for transfer. Transfer design criteria must include a complexity or variation that make learners engage critical thinking skills and call upon a repertoire of knowledge…

  20. Pre-K as School Turnaround Strategy

    Science.gov (United States)

    Buenafe, Anthony Q.

    2011-01-01

    Both state and local school systems, recognizing the strong and growing evidence of pre-kindergarten's effectiveness in closing achievement gaps, are implementing early learning programs as part of their education reform efforts. In low-performing districts, pre-k has emerged as a promising turnaround strategy, reaching children before they become…

  1. Metas' turnaround case: a study about the turnaround strategies and the related decision streams shaping them

    OpenAIRE

    Tüzüner, Tolga

    1995-01-01

    Ankara : The Department of Business Administration of Bilkent Univ., 1995. Thesis (Master's) -- Bilkent University, 1995. Includes bibliographical references. Meta§ which is the first private steel factory with arc furnace technology, begins to implement the “turnaround” strategy during the 90’s. This case aims to determine the reasons that cause the turnaround strategy and the strategic decision streams through the turnaround. Meta$ could not succeed financially in the e...

  2. Optimum short-time polynomial regression for signal analysis

    Indian Academy of Sciences (India)

    A Sreenivasa Murthy

    the Proceedings of European Signal Processing Conference. (EUSIPCO) 2008. ... In a seminal paper, Savitzky and Golay [4] showed that short-time polynomial modeling is ...... We next consider a linearly frequency-modulated chirp with an exponentially .... 1 http://www.physionet.org/physiotools/matlab/ECGwaveGen/.

  3. X-ray testing for short-time dynamic applications

    International Nuclear Information System (INIS)

    Kurfiss, Malte; Moser, Stefan; Popko, Gregor; Nau, Siegfried

    2017-01-01

    For nondestructive testing purposes new challenges are short-time dynamic processes. The application of x-ray flash tubes and modern high-speed cameras allows the observation of the opening of air-bags or the energy absorption of compressed tubes as occurring during a vehicle crash. Special algorithms designed for computerized tomography analyses allow the 3D reconstruction at individual time points of the dynamic process. Possibilities and limitations of the actual techniques are discussed.

  4. The case of escape probability as linear in short time

    Science.gov (United States)

    Marchewka, A.; Schuss, Z.

    2018-02-01

    We derive rigorously the short-time escape probability of a quantum particle from its compactly supported initial state, which has a discontinuous derivative at the boundary of the support. We show that this probability is linear in time, which seems to be a new result. The novelty of our calculation is the inclusion of the boundary layer of the propagated wave function formed outside the initial support. This result has applications to the decay law of the particle, to the Zeno behaviour, quantum absorption, time of arrival, quantum measurements, and more.

  5. Short Sleep Times Predict Obesity in Internal Medicine Clinic Patients

    Science.gov (United States)

    Buscemi, Dolores; Kumar, Ashwani; Nugent, Rebecca; Nugent, Kenneth

    2007-01-01

    Study Objectives: Epidemiological studies have demonstrated an association between short sleep times and obesity as defined by body mass index (BMI). We wanted to determine whether this association occurs in patients with chronic medical diagnoses since the number of confounding factors is likely higher in patients than the general population. Methods: Two hundred patients attending internal medicine clinics completed a survey regarding sleep habits, lifestyle characteristics, and medical diagnoses. An independent surveyor collected the information on the questionnaires and reviewed the medical records. Height and weight were measured by clinic personnel. Data were analyzed with multivariate logistic regression. Results: Subjects with short sleep times (< 7 hours) had an increased likelihood of obesity as defined by a BMI ≥ 30 kg/m2 when compared to the reference group of (8, 9] hours (odds ratio 2.93; 95% confidence interval, 1.06–8.09). There was a U-shaped relationship between obesity and sleep time in women but not in men. Young age (18 to 49 years), not smoking, drinking alcohol, hypertension, diabetes, and sleep apnea were also associated with obesity in the overall model. Conclusions: This study demonstrates an association between short sleep times and obesity in undifferentiated patients attending an internal medicine clinic using models adjusting for age, lifestyle characteristics, and some medical diagnoses. The U-shaped relationship in women suggests that sleep patterns may have gender specific associations. These observations provide the background for therapeutic trials in weight loss in patients with established medical problems. Citation: Buscemi D; Kumar A; Nugent R; Nugent K. Short sleep times predict obesity in internal medicine clinic patients. J Clin Sleep Med 2007;3(7):681–688. PMID:18198800

  6. Short echo time, fast gradient-echo imaging

    International Nuclear Information System (INIS)

    Haacke, E.M.; Lenz, G.W.

    1987-01-01

    Present fast-gradient-echoes schemes can acquire volume data rapidly and are flexible in T1 or T1/T2 contrast behavior. However, sequences used to date employ echo time (TE) values of about 15 ms +- 5 and, because of in vivo field inhomogeneities (short T2), they suffer badly from signal loss near sinuses and tissue boundaries. The authors implemented sequences with TE = 4-6 ms and found significant improvement in image quality, especially at high fields. Examples with long TEs vs. short TEs are given in the knee, spine, head, and orbits. Further advantages include (1) faster repetition times (15 ms), (2) higher-quality spin-density or T1-weighted images, and (3) reduction of blood motion artifacts

  7. Inducement and responsibility in the energy turnaround

    International Nuclear Information System (INIS)

    Loewer, Wolfgang

    2013-01-01

    The book includes several contributions concerning the Bonn discussion on energy legislation (volume 7): inducement and responsibility -in terms of constitutional law; between Europe and re-regulation - what is the regulation framework? Continuity requirement as legislative action directive; the future of the nuclear fuel tax after the nuclear phaseout - problems of the constitutional finance and the European tax legislation, strategy and energy markets; regulatory challenges in the realization of the energy turnaround policy.

  8. The short time Fourier transform and local signals

    Science.gov (United States)

    Okumura, Shuhei

    In this thesis, I examine the theoretical properties of the short time discrete Fourier transform (STFT). The STFT is obtained by applying the Fourier transform by a fixed-sized, moving window to input series. We move the window by one time point at a time, so we have overlapping windows. I present several theoretical properties of the STFT, applied to various types of complex-valued, univariate time series inputs, and their outputs in closed forms. In particular, just like the discrete Fourier transform, the STFT's modulus time series takes large positive values when the input is a periodic signal. One main point is that a white noise time series input results in the STFT output being a complex-valued stationary time series and we can derive the time and time-frequency dependency structure such as the cross-covariance functions. Our primary focus is the detection of local periodic signals. I present a method to detect local signals by computing the probability that the squared modulus STFT time series has consecutive large values exceeding some threshold after one exceeding observation following one observation less than the threshold. We discuss a method to reduce the computation of such probabilities by the Box-Cox transformation and the delta method, and show that it works well in comparison to the Monte Carlo simulation method.

  9. Evaluation of scaling invariance embedded in short time series.

    Directory of Open Access Journals (Sweden)

    Xue Pan

    Full Text Available Scaling invariance of time series has been making great contributions in diverse research fields. But how to evaluate scaling exponent from a real-world series is still an open problem. Finite length of time series may induce unacceptable fluctuation and bias to statistical quantities and consequent invalidation of currently used standard methods. In this paper a new concept called correlation-dependent balanced estimation of diffusion entropy is developed to evaluate scale-invariance in very short time series with length ~10(2. Calculations with specified Hurst exponent values of 0.2,0.3,...,0.9 show that by using the standard central moving average de-trending procedure this method can evaluate the scaling exponents for short time series with ignorable bias (≤0.03 and sharp confidential interval (standard deviation ≤0.05. Considering the stride series from ten volunteers along an approximate oval path of a specified length, we observe that though the averages and deviations of scaling exponents are close, their evolutionary behaviors display rich patterns. It has potential use in analyzing physiological signals, detecting early warning signals, and so on. As an emphasis, the our core contribution is that by means of the proposed method one can estimate precisely shannon entropy from limited records.

  10. Evaluation of scaling invariance embedded in short time series.

    Science.gov (United States)

    Pan, Xue; Hou, Lei; Stephen, Mutua; Yang, Huijie; Zhu, Chenping

    2014-01-01

    Scaling invariance of time series has been making great contributions in diverse research fields. But how to evaluate scaling exponent from a real-world series is still an open problem. Finite length of time series may induce unacceptable fluctuation and bias to statistical quantities and consequent invalidation of currently used standard methods. In this paper a new concept called correlation-dependent balanced estimation of diffusion entropy is developed to evaluate scale-invariance in very short time series with length ~10(2). Calculations with specified Hurst exponent values of 0.2,0.3,...,0.9 show that by using the standard central moving average de-trending procedure this method can evaluate the scaling exponents for short time series with ignorable bias (≤0.03) and sharp confidential interval (standard deviation ≤0.05). Considering the stride series from ten volunteers along an approximate oval path of a specified length, we observe that though the averages and deviations of scaling exponents are close, their evolutionary behaviors display rich patterns. It has potential use in analyzing physiological signals, detecting early warning signals, and so on. As an emphasis, the our core contribution is that by means of the proposed method one can estimate precisely shannon entropy from limited records.

  11. Application of short-time activation analysis in the sciences

    International Nuclear Information System (INIS)

    Grass, F.

    1991-01-01

    Short-time activation analysis has proved to be a valuable tool in nearly all fields of science. To take full advantage of this technique, it is favorable to use a fast transfer system and a high resolution high rate gamma-spectroscopy system for short lived gamma-emitters and a Cherenkov detector for the determination of hard beta-emitters. It is then possible to utilize sub-minute nuclides Li-8 (740 ms), B-12 (20 ms), F-20 (11.1 s), Y-89m (16 s), and Pb-207m (800 ms) for the determination of these elements. Besides these sub-minute nuclides which constitute the only possibility for neutron activation analysis of these elements there are a number of other elements which form longer lived nuclides on short irradiation. The analysis of the halogenides F, Cl, Br, I in waste water of a sewage incineration plant can be achieved with a single 20 s irradiation and two consecutive measurement of 20 and 600 s using Cl-38m, F-20, Br-79m as well as the longer lived Cl-38, Br-80, I-128

  12. Short-time perturbation theory and nonrelativistic duality

    International Nuclear Information System (INIS)

    Whitenton, J.B.; Durand, B.; Durand, L.

    1983-01-01

    We give a simple proof of the nonrelativistic duality relation 2 sigma/sub bound/>roughly-equal 2 sigma/sub free/> for appropriate energy averages of the cross sections for e + e - →(qq-bar bound states) and e + e - →(free qq-bar pair), and calculate the corrections to the relation by relating W 2 sigma to the Fourier transform of the Feynman propagation function and developing a short-time perturbation series for that function. We illustrate our results in detail for simple power-law potentials and potentials which involve combinations of powers

  13. Directional short-time Fourier transform of distributions

    Directory of Open Access Journals (Sweden)

    Katerina Hadzi-Velkova Saneva

    2016-04-01

    Full Text Available Abstract In this paper we consider the directional short-time Fourier transform (DSTFT that was introduced and investigated in (Giv in J. Math. Anal. Appl. 399:100-107, 2013. We analyze the DSTFT and its transpose on test function spaces S ( R n $\\mathcal {S}(\\mathbb {R}^{n}$ and S ( Y 2 n $\\mathcal {S}(\\mathbb {Y}^{2n}$ , respectively, and prove the continuity theorems on these spaces. Then the obtained results are used to extend the DSTFT to spaces of distributions.

  14. Leading a supply chain turnaround.

    Science.gov (United States)

    Slone, Reuben E

    2004-10-01

    Just five years ago, salespeople at Whirlpool were in the habit of referring to their supply chain organization as the "sales disablers." Now the company excels at getting products to the right place at the right time--while managing to keep inventories low. How did that happen? In this first-person account, Reuben Slone, Whirlpool's vice president of Global Supply Chain, describes how he and his colleagues devised the right supply chain strategy, sold it internally, and implemented it. Slone insisted that the right focal point for the strategy was the satisfaction of consumers at the end of the supply chain. Most supply chain initiatives do the opposite: They start with the realities of a company's manufacturing base and proceed from there. Through a series of interviews with trade customers large and small, his team identified 27 different capabilities that drove industry perceptions of Whirlpool's performance. Knowing it was infeasible to aim for world-class performance across all of them, Slone weighed the costs of excelling at each and found the combination of initiatives that would provide overall competitive advantage. A highly disciplined project management office and broad training in project management were key to keeping work on budget and on benefit. Slone set an intense pace--three "releases" of new capabilities every month--that the group maintains to this day. Lest this seem like a technology story, however, Slone insists it is just as much a "talent renaissance." People are proud today to be part of Whirlpool's supply chain organization, and its new generation of talent will give the company a competitive advantage for years to come.

  15. IEC ready for turnaround in nuclear industry

    International Nuclear Information System (INIS)

    Schomberg, R.; Corte, E.; Thompson, I.

    2005-01-01

    The activity of IEC Technical Committee (TC) 45 (Nuclear Instrumentation) in conditions of turnaround in nuclear industry is considered. TC 45's main task is to lay down a comprehensive strategy for itself and its two subcommittees as well as to improve the relevance of the nuclear safety standards. Subcommittee 45A develops standards that apply to the electronic and electrical functions and associated systems and equipment used in the instrumentation and control systems of nuclear energy generation facilities. Subcommittee 45B develops and issues standards covering all aspects of instrumentation associated with radiation protection including radiation detectors, radiation monitoring, dosimetry and radiology [ru

  16. EVOLVING TO TYPE Ia SUPERNOVAE WITH SHORT DELAY TIMES

    International Nuclear Information System (INIS)

    Wang Bo; Chen Xuefei; Han Zhanwen; Meng Xiangcun

    2009-01-01

    The single-degenerate model is currently a favorable progenitor model for Type Ia supernovae (SNe Ia). Recent investigations on the white dwarf (WD) + He star channel of the single-degenerate model imply that this channel is noteworthy for producing SNe Ia. In this paper, we studied SN Ia birthrates and delay times of this channel via a detailed binary population synthesis approach. We found that the Galactic SN Ia birthrate from the WD + He star channel is ∼0.3 x 10 -3 yr -1 according to our standard model, and that this channel can explain SNe Ia with short delay times (∼4.5 x 10 7 -1.4 x 10 8 yr). Meanwhile, these WD + He star systems may be related to the young supersoft X-ray sources prior to SN Ia explosions.

  17. Ozone impact minimization through coordinated scheduling of turnaround operations from multiple olefin plants in an ozone nonattainment area

    Science.gov (United States)

    Ge, Sijie; Wang, Sujing; Xu, Qiang; Ho, Thomas

    2018-03-01

    Turnaround operations (start-up and shutdown) are critical operations in olefin plants, which emit large quantities of VOCs, NOx and CO. The emission has great potentials to impact the ozone level in ozone nonattainment areas. This study demonstrates a novel practice to minimize the ozone impact through coordinated scheduling of turnaround operations from multiple olefin plants located in Houston, Texas, an ozone nonattainment area. The study considered two olefin plants scheduled to conduct turnaround operations: one start-up and one shutdown, simultaneously on the same day within a five-hour window. Through dynamic simulations of the turnaround operations using ASPEN Plus Dynamics and air quality simulations using CAMx, the study predicts the ozone impact from the combined effect of the two turnaround operations under different starting-time scenarios. The simulations predict that the ozone impact from planned turnaround operations ranges from a maximum of 11.4 ppb to a minimum of 1.4 ppb. Hence, a reduction of up to 10.0 ppb can be achieved on a single day based on the selected two simulation days. This study demonstrates a cost-effective and environmentally benign ozone control practice for relevant stakeholders, including environmental agencies, regional plant operators, and local communities.

  18. Decision time horizon for music genre classification using short time features

    DEFF Research Database (Denmark)

    Ahrendt, Peter; Meng, Anders; Larsen, Jan

    2004-01-01

    In this paper music genre classification has been explored with special emphasis on the decision time horizon and ranking of tapped-delay-line short-time features. Late information fusion as e.g. majority voting is compared with techniques of early information fusion such as dynamic PCA (DPCA......). The most frequently suggested features in the literature were employed including mel-frequency cepstral coefficients (MFCC), linear prediction coefficients (LPC), zero-crossing rate (ZCR), and MPEG-7 features. To rank the importance of the short time features consensus sensitivity analysis is applied...

  19. Short-time action electric generators to power physical devices

    International Nuclear Information System (INIS)

    Glebov, I.A.; Kasharskij, Eh.G.; Rutberg, F.G.; Khutoretskij, G.M.

    1982-01-01

    Requirements to be met by power-supply sources of the native electrophysical facilities have been analyzed and trends in designing foreign electric machine units of short-time action have been considered. Specifications of a generator, manufactured in the form of synchronous bipolar turbogenerator with an all-forged rotor with indirect air cooling of the rotor and stator windings are presented. Front parts of the stator winding are additionally fixed using glass-textolite rings, brackets and gaskets. A flywheel, manufactured in the form of all-forged steel cylinder is joined directly with the generator rotor by means of a half-coupling. An acceleration asynchronous engine with a phase rotor of 4 MW nominal capacity is located on the opposite side of the flywheel. The generator peak power is 242 MVxA; power factor = 0.9; energy transferred to the load 5per 1 pulse =00 MJ; the flywheel weight 81 t

  20. The Effect of Locus of Control on School Turnaround

    Science.gov (United States)

    Walston, Bradford

    2012-01-01

    This research focused on the school turnaround process in six turnaround elementary schools located in urban and rural areas of the state of North Carolina. The purpose of the study was to learn about the challenges facing the six schools, the process of improving student achievement, and, more specifically, the degree to which adaptive leadership…

  1. "Turnaround" as Shock Therapy: Race, Neoliberalism, and School Reform

    Science.gov (United States)

    Johnson, Amanda Walker

    2013-01-01

    "Turnaround" strategies of educational reform promise that school closure, reconstitution, privatizing, and reopening them will bring miraculous results. Questioning the implications, this article situates "turnaround" strategies locally, following the closure of a predominantly minority high school in 2008, in Austin, Texas.…

  2. Forecast model of landslides in a short time

    International Nuclear Information System (INIS)

    Sanchez Lopez, Reinaldo

    2006-01-01

    The IDEAM in development of their functions as member of the national technical committee for the prevention and disasters attention (SNPAD) accomplishes the follow-up, monitoring and forecast in real time of the environmental dynamics that in extreme situations constitute threats and natural risks. One of the frequent dynamics and of greater impact is related to landslides, those that affect persistently the life of the persons, the infrastructure, the socioeconomic activities and the balance of the environment. The landslide in Colombia and in the world are caused mainly by effects of the rain, due to that, IDEAM has come developing forecast model, as an instrument for risk management in a short time. This article presents aspects related to their structure, operation, temporary space resolution, products, results, achievements and projections of the model. Conceptually, the model is support by the principle of the dynamic temporary - space, of the processes that consolidate natural hazards, particularly in areas where the man has come building the risk. Structurally, the model is composed by two sub-models; the general susceptibility of the earthly model and the critical rain model as a denotative factor, that consolidate the hazard process. In real time, the model, works as a GIS, permitting the automatic zoning of the landslides hazard for issue public advisory warming to help makers decisions on the risk that cause frequently these events, in the country

  3. Nonequilibrium Physics at Short Time Scales: Formation of Correlations

    International Nuclear Information System (INIS)

    Peliti, L

    2005-01-01

    It is a happy situation when similar concepts and theoretical techniques can be applied to widely different physical systems because of a deep similarity in the situations being studied. The book illustrates this well; it focuses on the description of correlations in quantum systems out of equilibrium at very short time scales, prompted by experiments with short laser pulses in semiconductors, and in complex reactions in heavy nuclei. In both cases the experiments are characterized by nonlinear dynamics and by strong correlations out of equilibrium. In some systems there are also important finite-size effects. The book comprises several independent contributions of moderate length, and I sometimes felt that a more intensive effort in cross-coordination of the different contributions could have been of help. It is divided almost equally between theory and experiment. In the theoretical part, there is a thorough discussion both of the kinematic aspects (description of correlations) and the dynamical ones (evaluation of correlations). The experimental part is naturally divided according to the nature of the system: the interaction of pulsed lasers with matter on the one hand, and the correlations in finite-size systems (nanoparticles and nuclei) on the other. There is also a discussion on the dynamics of superconductors, a subject currently of great interest. Although an effort has been made to keep each contribution self-contained, I must admit that reading level is uneven. However, there are a number of thorough and stimulating contributions that make this book a useful introduction to the topic at the level of graduate students or researchers acquainted with quantum statistical mechanics. (book review)

  4. The effect of short-time active listening training.

    Science.gov (United States)

    Tatsumi, Asami; Sumiyoshi, Kenichi; Kawaguchi, Hitomi; Sano, Yukiko

    2010-01-01

    We conducted mental health training incorporating active listening for managers at a site of a general chemical company with 1,400 employees. Our purpose was to clarify the effect of active listening training of 2.5h. All subjects were managers. The mental health training was given to 229 managers, 21 times from May 2007 until March 2008. Surveys were conducted from May 2007 to September 2008. The training sessions were conducted in a company meeting room, starting at 2:00 p.m. The importance and significance of listening as a mental health measure and methods of active listening were explained in the training. Afterward, role-playing and follow-up discussions were done twice each. In summaries, participants wrote down what they noticed about listening and gave group presentations. The instructor commented on the presentations, and ended the session by passing out and explaining a paper summarizing what is important in listening. The training was evaluated with a questionnaire distributed at the completion of training, and questionnaires on implementation of what was learned were distributed 1, 3, and 6 mo later. The Active Listening Attitude Scale (ALAS; composed of two scales for method of listening and listening attitude) developed by Mishima et al. was also used before and 1, 3, and 6 mo after the training. In questionnaires distributed on the same day after training, 60% of the 212 respondents said the training time was just right, and 30.1% felt it was too short. The difficulty level of the training was considered appropriate by 77.8%, and 79.7% intended to implement what they had learned. Overall satisfaction was high at 85.9%. In the questionnaire 6 mo after training, 81.4% of the 145 respondents remembered the content of the training and 49.7% said they were practicing what they had learned. They responded that their conversations with subordinates about non-work topics had increased, and communication and support at work had become smoother. ALAS was

  5. Innovation: study of 'ultra-short' time reactions

    International Nuclear Information System (INIS)

    Anon.

    2001-01-01

    This short article presents the new Elyse facility of Orsay-Paris 11 university for the study of ultra-short chemical and biochemical phenomena. Elyse uses the 'pump-probe' technique which consists in two perfectly synchronized electron and photon pulses. It comprises a 3 to 9 MeV electron accelerator with a HF gun photo-triggered with a laser. Elyse can initiate reactions using ultra-short electron pulses (radiolysis) or ultra-short photon pulses (photolysis). (J.S.)

  6. Job quality of short-time workers and perception and support from their managers

    OpenAIRE

    坂爪, 洋美

    2017-01-01

    The purpose of this study was to clarify the relationship between the characteristics of job quality that short-time workers occupied and the managers’ perception and support whose member has used short-time working hour system. A total of 559 first-line managers who has a member using short-time working hour system completed a web-based survey assessing job quality of short-time workers , the risk of using short-timeworking hour system, career perspective of short-time workers, and the suppo...

  7. Mechanistic models for cancer development after short time radiation exposure

    International Nuclear Information System (INIS)

    Kottbauer, M. M.

    1997-12-01

    In this work two biological based models were developed. First the single-hit model for solid tumors (SHM-S) and second the single-hit model for leukemia (SHM-L). These models are a further development of the Armitage-Doll model for the special case of a short time radiation exposure. The basis of the models is the multistage process of carcinogeneses. The single-hit models provide simultaneously the age-dependent cancer-rate of spontaneous and radiation induced tumors as well as the dose-effect relationships at any age after exposure. The SHM-S leads to a biological based dose-effect relationship, which is similar to the relative risk model suggested by the ICRP 60. The SHM-S describes the increased mortality rate of the bomb survivors more accurate than the relative risk model. The SHM-L results in an additive dose-effect relationship. It is shown that only small differences in the derivation of the two models lead to the two dose-effect relationships. Beside the radiation exposure the new models consider the decrease of the cancer mortality rate at higher ages (age>75) which can be traced back mainly to three causes: competitive causes of death, reduction of cell proliferation and reduction of risk groups. The single-hit models also consider children cancer, the different rates of incidence and mortality, influence of the immune system and the cell-killing effect. (author)

  8. Short-time home coming project in evacuation zone

    International Nuclear Information System (INIS)

    Tatsuzaki, Hideo

    2011-01-01

    Accident at Fukushima Daiichi Nuclear Power Plants (NPPs) forced neighboring residents to evacuate, and evacuation zone (20 km radius from NPPs) was defined as highly contaminated and designated as no-entry zones. Residents had been obliged to live a refugee life for a longer period than expected. Short-time home coming project was initiated according to their requests. They came to the meeting place called transfer place (20 - 30 km radius from NPPs), wore protective clothing and personal dosimeter with having drinking water and came home in evacuation zone with staffs by bus. Their healthcare management professionals were fully prepared for emergency. After collecting necessary articles at home within two hours, they returned to the meeting place by bus for screening and dressing, and went back to refuge house. If screening data were greater than 13 kcpm using GM counters, partial body decontamination had been conducted by wiping and if greater than 100 kcpm, whole body decontamination was requested but not conducted. Dose rate of residents and staffs was controlled less than 1 mSv, which was alarm level of personal dosimeter. Stable iodine was prepared but actually not used. (T. Tanaka)

  9. Probabilistic eruption forecasting at short and long time scales

    Science.gov (United States)

    Marzocchi, Warner; Bebbington, Mark S.

    2012-10-01

    Any effective volcanic risk mitigation strategy requires a scientific assessment of the future evolution of a volcanic system and its eruptive behavior. Some consider the onus should be on volcanologists to provide simple but emphatic deterministic forecasts. This traditional way of thinking, however, does not deal with the implications of inherent uncertainties, both aleatoric and epistemic, that are inevitably present in observations, monitoring data, and interpretation of any natural system. In contrast to deterministic predictions, probabilistic eruption forecasting attempts to quantify these inherent uncertainties utilizing all available information to the extent that it can be relied upon and is informative. As with many other natural hazards, probabilistic eruption forecasting is becoming established as the primary scientific basis for planning rational risk mitigation actions: at short-term (hours to weeks or months), it allows decision-makers to prioritize actions in a crisis; and at long-term (years to decades), it is the basic component for land use and emergency planning. Probabilistic eruption forecasting consists of estimating the probability of an eruption event and where it sits in a complex multidimensional time-space-magnitude framework. In this review, we discuss the key developments and features of models that have been used to address the problem.

  10. Characteristics of Occupational Exposure to Benzene during Turnaround in the Petrochemical Industries.

    Science.gov (United States)

    Chung, Eun-Kyo; Shin, Jung-Ah; Lee, Byung-Kyu; Kwon, Jiwoon; Lee, Naroo; Chung, Kwang-Jae; Lee, Jong-Han; Lee, In-Seop; Kang, Seong-Kyu; Jang, Jae-Kil

    2010-09-01

    The level of benzene exposure in the petrochemical industry during regular operation has been well established, but not in turnaround (TA), where high exposure may occur. In this study, the characteristics of occupational exposure to benzene during TA in the petrochemical companies were investigated in order to determine the best management strategies and improve the working environment. This was accomplished by evaluating the exposure level for the workers working in environments where benzene was being produced or used as an ingredient during the unit process. From 2003 to 2008, a total of 705 workers in three petrochemical companies in Korea were studied. Long- and short-term (< 1 hr) samples were taken during TAs. TA was classified into three stages: shut-down, maintenance and start-up. All works were classified into 12 occupation categories. The long-term geometric mean (GM) benzene exposure level was 0.025 (5.82) ppm (0.005-42.120 ppm) and the short-term exposure concentration during TA was 0.020 (17.42) ppm (0.005-61.855 ppm). The proportions of TA samples exceeding the time-weighted average, occupational exposure level (TWA-OEL in Korea, 1 ppm) and the short-term exposure limit (STEL-OEL, 5 ppm) were 4.1% (20 samples of 488) and 6.0% (13 samples of 217), respectively. The results for the benzene exposure levels and the rates of exceeding the OEL were both statistically significant (p < 0.05). Among the 12 job categories of petrochemical workers, mechanical engineers, plumbers, welders, fieldman and scaffolding workers exhibited long-term samples that exceeded the OEL of benzene, and the rate of exceeding the OEL was statistically significant for the first two occupations (p < 0.05). These findings suggest that the periodic work environment must be assessed during non-routine works such as TA.

  11. Turnaround operations analysis for OTV. Volume 2: Detailed technical report

    Science.gov (United States)

    1988-01-01

    The objectives and accomplishments were to adapt and apply the newly created database of Shuttle/Centaur ground operations. Previously defined turnaround operations analyses were to be updated for ground-based OTVs (GBOTVs) and space-based OTVs (SBOTVs), design requirements identified for both OTV and Space Station accommodations hardware, turnaround operations costs estimated, and a technology development plan generated to develop the required capabilities. Technical and programmatic data were provided for NASA pertinent to OTV round and space operations requirements, turnaround operations, task descriptions, timelines and manpower requirements, OTV modular design and booster and Space Station interface requirements. SBOTV accommodations development schedule, cost and turnaround operations requirements, and a technology development plan for ground and space operations and space-based accommodations facilities and support equipment. Significant conclusion are discussed.

  12. On the Option Effects of Short-Time Work Arrangements

    NARCIS (Netherlands)

    Huisman, Kuno; Thijssen, J.J.J.

    2018-01-01

    We analyse the short term work (STW) regulations that several OECD countries introduced after the 2007 financial crisis. We view these measures as a collection of real options and study the dynamic effect of STW on the endogenous liquidation decision of the firm. While STW delays a firm’s

  13. Short (

    NARCIS (Netherlands)

    Telleman, Gerdien; den Hartog, Laurens

    2013-01-01

    Aim: This systematic review assessed the implant survival rate of short (<10 mm) dental implants installed in partially edentulous patients. A case report of a short implant in the posterior region have been added. Materials and methods: A search was conducted in the electronic databases of MEDLINE

  14. A time-to-amplitude converter with constant fraction timing discriminators for short time interval measurements

    International Nuclear Information System (INIS)

    Kostamovaara, J.; Myllylae, R.

    1985-01-01

    The construction and the performance of a time-to-amplitude converter equipped with constant fraction discriminators is described. The TAC consists of digital and analog parts which are constructed on two printed circuit boards, both of which are located in a single width NIM module. The dead time of the TAC for a start pulse which is not followed by a stop pulse within the time range of the device (proportional100 ns) is only proportional100 ns, which enables one to avoid counting rate saturation even with a high random input signal rate. The differential and integral nonlinearities of the TAC are better than +-1.5% and 0.05%, respectively. The resolution for input timing pulses of constant shape is 20 ps (fwhm), and less than 10 ps (fwhm) with a modification in the digital part. The walk error of the constant fraction timing discriminators is presented and various parameters affecting it are discussed. The effect of the various disturbances in linearity caused by the fast ECL logic and their minimization are also discussed. The time-to-amplitude converter has been used in positron lifetime studies and for laser range finding. (orig.)

  15. Improving the turnaround maintenance of the Escravos gas plant / Ishekwene, I.V.

    OpenAIRE

    Ishekwene, Isaac Victor

    2011-01-01

    According to Oliver (2002) the success of turnaround maintenances is measured in terms of the cost of completion, time, safety performance and the performance of the plant afterwards. The Escravos gas plant (EGP) is a gas processing plant that converts associated gas from Chevron owned crude oil wells to liquefied petroleum gas, natural gas and gas condensate (Chevron intranet. Website assessed on September 14, 2007). According to the EGP plant operations coordinator (See inter...

  16. SHORT COMMUNICATION: Time measurement device with four femtosecond stability

    Science.gov (United States)

    Panek, Petr; Prochazka, Ivan; Kodet, Jan

    2010-10-01

    We present the experimental results of extremely precise timing in the sense of time-of-arrival measurements in a local time scale. The timing device designed and constructed in our laboratory is based on a new concept using a surface acoustic wave filter as a time interpolator. Construction of the device is briefly described. The experiments described were focused on evaluating the timing precision and stability. Low-jitter test pulses with a repetition frequency of 763 Hz were generated synchronously to the local time base and their times of arrival were measured. The resulting precision of a single measurement was typically 900 fs RMS, and a timing stability TDEV of 4 fs was achieved for time intervals in the range from 300 s to 2 h. To our knowledge this is the best value reported to date for the stability of a timing device. The experimental results are discussed and possible improvements are proposed.

  17. Energy turnaround and expansion of the power grids as seen by the population; Energiewende und Stromnetzausbau aus Sicht der Bevoelkerung

    Energy Technology Data Exchange (ETDEWEB)

    Schumann, Diana; Fischer, Wolfgang; Hake, Juergen-Friedrich [Forschungszentrum Juelich GmbH (Germany). Inst. fuer Energie- und Klimaforschung, Systemforschung und Technologische Entwicklung (IEK-STE)

    2013-07-15

    The expansion of the power grids is a central component of the energy turnaround. However, time and again transmission line construction projects meet with opposition from parts of the population. For the purposes of implementing the energy turnaround it is therefore of interest to ask what factors could be significant for the degree of public acceptance of power transmission lines. Answers to this question are available from the results of a recent representative panel survey on the acceptance in the population of the transformation of the energy supply system.

  18. Real-time energy resources scheduling considering short-term and very short-term wind forecast

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Marco; Sousa, Tiago; Morais, Hugo; Vale, Zita [Polytechnic of Porto (Portugal). GECAD - Knowledge Engineering and Decision Support Research Center

    2012-07-01

    This paper proposes an energy resources management methodology based on three distinct time horizons: day-ahead scheduling, hour-ahead scheduling, and real-time scheduling. In each scheduling process the update of generation and consumption operation and of the storage and electric vehicles storage status are used. Besides the new operation conditions, the most accurate forecast values of wind generation and of consumption using results of short-term and very short-term methods are used. A case study considering a distribution network with intensive use of distributed generation and electric vehicles is presented. (orig.)

  19. An Integrated Gate Turnaround Management Concept Leveraging Big Data/Analytics for NAS Performance Improvements

    Science.gov (United States)

    Chung, William; Chachad, Girish; Hochstetler, Ronald

    2016-01-01

    The Integrated Gate Turnaround Management (IGTM) concept was developed to improve the gate turnaround performance at the airport by leveraging relevant historical data to support optimization of airport gate operations, which include: taxi to the gate, gate services, push back, taxi to the runway, and takeoff, based on available resources, constraints, and uncertainties. By analyzing events of gate operations, primary performance dependent attributes of these events were identified for the historical data analysis such that performance models can be developed based on uncertainties to support descriptive, predictive, and prescriptive functions. A system architecture was developed to examine system requirements in support of such a concept. An IGTM prototype was developed to demonstrate the concept using a distributed network and collaborative decision tools for stakeholders to meet on time pushback performance under uncertainties.

  20. Successful integration of fast track projects into turnarounds

    Energy Technology Data Exchange (ETDEWEB)

    Williams, J. Patrick; Loureiro, Ramon C. [KBC Advanced Technologies, Surrey (United Kingdom)

    2012-07-01

    Fast track projects can provide quick wins and competitive advantage. However, in most cases the implementation of these projects requires a shutdown for installing the necessary tie-ins or integration into an upcoming turnaround (TA). Depending on the nature of the project and complexity of the TA, the integration can be seamless or result in cost or duration overruns and safety incidents. The risk of such overruns and safety incidents increases with the amount of project work to be integrated into the operations, maintenance and inspection schedules to be executed during the TA. The risk further increases with TA size and other factors. If not planned and scheduled properly and in a timely fashion, capital projects, in particular fast track projects trying to take advantage of an upcoming TA, can severely impact both TA performance, and the safety and reliability of the facility until the next opportunity for eliminating the defects introduced during the TA. Successful TAs are those delivered in a safe, on time, on budget manner, and with the quality standards needed for a leak-free start-up and a safe and reliable operation over the next run cycle. This paper discusses the key elements that are required to minimize the TA risks derived from the inclusion of fast track projects and how to establish the cut off criteria to either cancel or defer the project, or delay the TA in order to balance TA scope freeze and the case for compelling economics.(author)

  1. The history of time a very short introduction

    CERN Document Server

    Holford-Strevens, Leofranc

    2005-01-01

    Leofranc Holford-Strevens explores time measurement and the organisation of time into hours, days, months and years using a range of fascinating examples from Ancient Rome and Julius Caesar's Leap Year, to the 1920s' project for a fixed Easter. - ;Why do we measure time in the way that we do? Why is a week seven days long? At what point did minutes and seconds come into being? Why are some calendars lunar and some solar? The organisation of time into hours, days, months and years seems immutable and universal, but is actually far more artificial than most people realise. The French Revolution

  2. Short Vigilance Tasks are Hard Work Even If Time Flies

    Science.gov (United States)

    2016-10-21

    maintaining the data needed , and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other...actual time. Upon completion of the task, participants filled out questionnaires related to the hedonic and temporal evaluation of the task. Participants...time. Upon completion of the task, participants filled out questionnaires related to the hedonic and temporal evaluation of the task. Participants

  3. Defining Business decline, failure and turnaround: A content analysis

    Directory of Open Access Journals (Sweden)

    Marius Pretorius

    2009-12-01

    Full Text Available In the past, researchers have often defined failure to suit their data. This has led to a lack of comparability in research outputs. The overriding objective of this paper is to propose a universal definition for the failure phenomenon. Clear definitions are a prerequisite for exploring major constructs, their relationship to failure and the context and processes involved. The study reports on the core definitions of the failure phenomenon and identifies core criteria for distinguishing between them. It places decline, failure and turnaround in perspective and highlights level of distress and turnaround as key moderating elements. It distinguishes the failure phenomenon from controversial synonyms such as closure, accidental bankruptcy and closure for alternative motives. Key words and phrases: business decline, failure, turnaround, level of distress

  4. Perception of short time scale intervals in a hypnotic virtuoso

    NARCIS (Netherlands)

    Noreika, Valdas; Falter, Christine M.; Arstila, Valtteri; Wearden, John H.; Kallio, Sakari

    2012-01-01

    Previous studies showed that hypnotized individuals underestimate temporal intervals in the range of several seconds to tens of minutes. However, no previous work has investigated whether duration perception is equally disorderly when shorter time intervals are probed. In this study, duration

  5. Dollars and Deadlines: Rule Reforms in Short Time Frames

    Science.gov (United States)

    ABSTRACT: In "At Last! Aye, and there's the Rub" (i.e., the target article for this commentary), Capron describes challenges related to the timing for development, adoption, and revision of the Common Rule. Specifically, what the National Commission thought would be a...

  6. Tests for nonlinearity in short stationary time series

    International Nuclear Information System (INIS)

    Chang, T.; Sauer, T.; Schiff, S.J.

    1995-01-01

    To compare direct tests for detecting determinism in chaotic time series, data from Henon, Lorenz, and Mackey--Glass equations were contaminated with various levels of additive colored noise. These data were analyzed with a variety of recently developed tests for determinism, and the results compared

  7. PASTEURISASI HIGH TEMPERATURE SHORT TIME (HTST) SUSU TERHADAP Listeria monocytogenes PADA PENYIMPANAN REFRIGERATOR

    OpenAIRE

    SABIL, SYAHRIANA

    2015-01-01

    2015 SYAHRIANA SABIL (I 111 11 273). Pasteurisasi High Temperature Short Time (HTST) Susu terhadap Listeria monocytogenes pada Penyimpanan Refrigerator. Dibimbing oleh RATMAWATI MALAKA dan FARIDA NUR YULIATI. Pasteurisasi High Temperature Short Time (HTST) merupakan proses pemanasan susu di bawah titik didih yang diharapkan dapat membunuh Listeria monocytogenes (L. monocytogenes) karena bersifat patogen dan mengakibatkan listeriosis yang merupakan penyakit zoonosis. Tu...

  8. Research for the energy turnaround. Phase transitions actively shape. Contributions

    International Nuclear Information System (INIS)

    Szczepanski, Petra; Wunschick, Franziska; Martin, Niklas

    2015-01-01

    The Annual Conference 2014 of the Renewable Energy Research Association was held in Berlin on 6 and 7 November 2014. This book documents the contributions of the conference on research for the energy turnaround, phase transitions actively shape. After an introduction and two contributions to the political framework, the contributions to the economic phases of the energy transition, the phase of the current turn, the phases of social energy revolution, the stages of heat turnaround (Waermewende), and the stages of the mobility turn deal with the stages of development of the energy system. Finally, the Research Association Renewable Energy is briefly presented. [de

  9. Time manages interference in visual short-term memory.

    Science.gov (United States)

    Smith, Amy V; McKeown, Denis; Bunce, David

    2017-09-01

    Emerging evidence suggests that age-related declines in memory may reflect a failure in pattern separation, a process that is believed to reduce the encoding overlap between similar stimulus representations during memory encoding. Indeed, behavioural pattern separation may be indexed by a visual continuous recognition task in which items are presented in sequence and observers report for each whether it is novel, previously viewed (old), or whether it shares features with a previously viewed item (similar). In comparison to young adults, older adults show a decreased pattern separation when the number of items between "old" and "similar" items is increased. Yet the mechanisms of forgetting underpinning this type of recognition task are yet to be explored in a cognitively homogenous group, with careful control over the parameters of the task, including elapsing time (a critical variable in models of forgetting). By extending the inter-item intervals, number of intervening items and overall decay interval, we observed in a young adult sample (N = 35, M age  = 19.56 years) that the critical factor governing performance was inter-item interval. We argue that tasks using behavioural continuous recognition to index pattern separation in immediate memory will benefit from generous inter-item spacing, offering protection from inter-item interference.

  10. Policy Perspective: School Turnaround in England. Utilizing the Private Sector

    Science.gov (United States)

    Corbett, Julie

    2014-01-01

    This paper, written by strategic partner of the Center on School Turnaround (CST), Julie Corbett, provides research and examples on England's approach to turning around its lowest performing schools. The English education system utilizes private vendors to support chronically low-performing schools and districts. The introduction is followed by…

  11. Mixing Metaphors: Building Infrastructure for Large Scale School Turnaround

    Science.gov (United States)

    Peurach, Donald J.; Neumerski, Christine M.

    2015-01-01

    The purpose of this analysis is to increase understanding of the possibilities and challenges of building educational infrastructure--the basic, foundational structures, systems, and resources--to support large-scale school turnaround. Building educational infrastructure often exceeds the capacity of schools, districts, and state education…

  12. Transforming Turnaround Schools in China: Strategies, Achievements, and Challenges

    Science.gov (United States)

    Liu, Peng

    2016-01-01

    The existence of turnaround schools has been a problem in the Chinese education system. There are diverse causes including the education system itself, the financial system, and other issues. However, there has been a lack of research to help us fully understand this phenomenon. This article provides a holistic perspective on the strategies the…

  13. Short-term adaptations as a response to travel time: results of a stated adaptation experimentincreases

    NARCIS (Netherlands)

    Psarra, I.; Arentze, T.A.; Timmermans, H.J.P.

    2016-01-01

    This study focused on short-term dynamics of activity-travel behavior as a response to travel time increases. It is assumed that short-term changes are triggered by stress, which is defined as the deviation between an individual’s aspirations and his or her daily experiences. When stress exceeds a

  14. Determination of rail wear and short-time wear measurements of rails applying radioisotopes

    International Nuclear Information System (INIS)

    Grohmann, H.D.

    1981-01-01

    An energetic model has been developed for calculating rail wear. Short-time wear tests on rails after surface activation and following activity measurements showed a good agreement with the calculated values

  15. Determination of Permissible Short-Time Emergency Overloading of Turbo-Generators and Synchronous Compensators

    Directory of Open Access Journals (Sweden)

    V. A. Anischenko

    2011-01-01

    Full Text Available The paper shows that failure to take into account variable ratio of short-time emergency overloading of turbo-generators (synchronous compensators that can lead to underestimation of overloading capacity or impermissible insulation over-heating.A method has been developed for determination of permissible duration of short-time emergency over-loading that takes into account changes of over-loading ratio in case of a failure.

  16. Time-dependent Bragg diffraction and short-pulse reflection by one-dimensional photonic crystals

    International Nuclear Information System (INIS)

    André, Jean-Michel; Jonnard, Philippe

    2015-01-01

    The time-dependence of the Bragg diffraction by one-dimensional photonic crystals and its influence on the short pulse reflection are studied in the framework of the coupled-wave theory. The indicial response of the photonic crystal is calculated and it appears that it presents a time-delay effect with a transient time conditioned by the extinction length. A numerical simulation is presented for a Bragg mirror in the x-ray domain and a pulse envelope modelled by a sine-squared shape. The potential consequences of the time-delay effect in time-dependent optics of short-pulses are emphasized. (paper)

  17. Temporal Prediction Errors Affect Short-Term Memory Scanning Response Time.

    Science.gov (United States)

    Limongi, Roberto; Silva, Angélica M

    2016-11-01

    The Sternberg short-term memory scanning task has been used to unveil cognitive operations involved in time perception. Participants produce time intervals during the task, and the researcher explores how task performance affects interval production - where time estimation error is the dependent variable of interest. The perspective of predictive behavior regards time estimation error as a temporal prediction error (PE), an independent variable that controls cognition, behavior, and learning. Based on this perspective, we investigated whether temporal PEs affect short-term memory scanning. Participants performed temporal predictions while they maintained information in memory. Model inference revealed that PEs affected memory scanning response time independently of the memory-set size effect. We discuss the results within the context of formal and mechanistic models of short-term memory scanning and predictive coding, a Bayes-based theory of brain function. We state the hypothesis that our finding could be associated with weak frontostriatal connections and weak striatal activity.

  18. The energy turnaround in Switzerland; Die Energiewende der Schweiz

    Energy Technology Data Exchange (ETDEWEB)

    Vollrath, Klaus [Redaktionsbuero Klaus Vollrath, Aarwangen (Switzerland)

    2012-12-15

    Not only Germany, Switzerland, too, has opted for an energy turnaround to resolve the question as to its future electricity supply. The decision envisages the decommissioning without replacement of all five existing nuclear power plants. In the debate over possible alternative concepts we are seeing a violent clash between different energy policy positions within the population, the political realm and in the media. If one thing is sure, it is that it will not be cheap.

  19. Rapid-cycle testing cuts bed turnaround by 85%.

    Science.gov (United States)

    2004-11-01

    You can use rapid-cycle testing to try out new approaches to overcrowding much more frequently than with more traditional process improvement strategies. Improving bed turnaround notification can yield dramatic improvements. Telling staff they have to try a new process only for three days makes it easier to gain buy-in. Look for old policies that are no longer needed, yet continue to keep your staff bogged down.

  20. Psychometric properties of the Hebrew short version of the Zimbardo Time Perspective Inventory.

    Science.gov (United States)

    Orkibi, Hod

    2015-06-01

    The purpose of this study was to develop a short Hebrew version of the Zimbardo Time Perspective Inventory that can be easily administered by health professionals in research, therapy, and counseling. First, the empirical links of time perspective (TP) to subjective well-being and health protective and health risk behaviors are reviewed. Then, a brief account of the instrument's previous modifications is provided. Results of confirmatory factor analysis (N = 572) verified the five-factor structure of the short version and yielded acceptable internal consistency reliability for each factor. The correlation coefficients between the five subscales of the short (20 items) and the original (56 items) instruments were all above .79, indicating the suitability of the short version for assessing the five TP factors. Support for the discriminant and concurrent validity was also achieved, largely in agreement with previous findings. Finally, limitations and future directions are addressed, and potential applications in therapy and counseling are offered. © The Author(s) 2014.

  1. Real-time mobile customer short message system design and implementation

    Science.gov (United States)

    Han, Qirui; Sun, Fang

    To expand the current mobile phone short message service, and to make the contact between schools, teachers, parents and feedback of the modern school office system more timely and conveniently, designed and developed the Short Message System based on the Linux platform. The state-of-the-art principles and designed proposals in the Short Message System based on the Linux platform are introduced. Finally we propose an optimized secure access authentication method. At present, many schools,vbusinesses and research institutions ratify the promotion and application the messaging system gradually, which has shown benign market prospects.

  2. Active mode-locking of mid-infrared quantum cascade lasers with short gain recovery time.

    Science.gov (United States)

    Wang, Yongrui; Belyanin, Alexey

    2015-02-23

    We investigate the dynamics of actively modulated mid-infrared quantum cascade lasers (QCLs) using space- and time-domain simulations of coupled density matrix and Maxwell equations with resonant tunneling current taken into account. We show that it is possible to achieve active mode locking and stable generation of picosecond pulses in high performance QCLs with a vertical laser transition and a short gain recovery time by bias modulation of a short section of a monolithic Fabry-Perot cavity. In fact, active mode locking in QCLs with a short gain recovery time turns out to be more robust to the variation of parameters as compared to previously studied lasers with a long gain recovery time. We investigate the effects of spatial hole burning and phase locking on the laser output.

  3. A short-time fading study of Al2O3:C

    International Nuclear Information System (INIS)

    Nascimento, L.F.; Vanhavere, F.; Silva, E.H.; Deene, Y. De

    2015-01-01

    This paper studies the short-time fading from Al 2 O 3 :C by measuring optically stimulated luminescence (OSL) signals (Total OSL: T OSL , and Peak OSL: P OSL ) from droplets and Luxel™ pellets. The influence of various bleaching regimes (blue, green and white) and light power is compared. The fading effect is the decay of the OSL signal in the dark at room temperature. Al 2 O 3 :C detectors were submitted to various bleaching regimes, irradiated with a reference dose and read out after different time spans. Investigations were carried out using 2 mm size droplet detectors, made of thin Al 2 O 3 :C powder mixed with a photocured polymer. Tests were compared to Luxel™-type detectors (Landauer Inc.). Short-time post-irradiation fading is present in OSL results (T OSL and P OSL ) droplets for time spans up to 200 s. The effect of short-time fading can be lowered/removed when treating the detectors with high-power and/or long time bleaching regimes; this result was observed in both T OSL and P OSL from droplets and Luxel™. - Highlights: • Droplet composed of thin powder of Al 2 O 3 :C was prepared using a photo-curable polymer. • Powder grain sizes ranged from 5 μm to 35 μm. • Short-time fading was measured for irradiated samples. • Various bleaching regimes and light power was tested. • Droplets were compared to a commercially dosimeter, Luxel™

  4. Ultra-short time sciences. From the atto-second to the peta-watts

    International Nuclear Information System (INIS)

    2000-01-01

    This book presents the recent advances in the scientific and technical domains linked with ultra-short time physics. It deals first with the conceptual and technological aspects of ultra-intense and ultra-brief lasers. Then, it describes the different domains of research (atoms, molecules and aggregates; gaseous phase dynamics using the pump-probe technique; femto-chemistry in dense phase; condensed matter; plasma physics; consistent control; aerosols; functional femto-biology) and the different domains of application (medical diagnosis; ophthalmology; telecommunications; technological and industrial developments). A last part is devoted to the teaching of ultra-short time sciences. (J.S.)

  5. Short-time, high-dosage penicillin infusion therapy of syphilis

    DEFF Research Database (Denmark)

    Lomholt, Hans; Poulsen, Asmus; Brandrup, Flemming

    2003-01-01

    The optimal dosage and duration of penicillin treatment for the various stages of syphilis are not known. We present data on 20 patients with syphilis (primary, secondary or latent) treated with high-dose, short-time penicillin infusion therapy. Patients were given 10 MIU of penicillin G intraven......The optimal dosage and duration of penicillin treatment for the various stages of syphilis are not known. We present data on 20 patients with syphilis (primary, secondary or latent) treated with high-dose, short-time penicillin infusion therapy. Patients were given 10 MIU of penicillin G...

  6. An Integrated Gate Turnaround Management Concept Leveraging Big Data Analytics for NAS Performance Improvements

    Science.gov (United States)

    Chung, William W.; Ingram, Carla D.; Ahlquist, Douglas Kurt; Chachad, Girish H.

    2016-01-01

    "Gate Turnaround" plays a key role in the National Air Space (NAS) gate-to-gate performance by receiving aircraft when they reach their destination airport, and delivering aircraft into the NAS upon departing from the gate and subsequent takeoff. The time spent at the gate in meeting the planned departure time is influenced by many factors and often with considerable uncertainties. Uncertainties such as weather, early or late arrivals, disembarking and boarding passengers, unloading/reloading cargo, aircraft logistics/maintenance services and ground handling, traffic in ramp and movement areas for taxi-in and taxi-out, and departure queue management for takeoff are likely encountered on the daily basis. The Integrated Gate Turnaround Management (IGTM) concept is leveraging relevant historical data to support optimization of the gate operations, which include arrival, at the gate, departure based on constraints (e.g., available gates at the arrival, ground crew and equipment for the gate turnaround, and over capacity demand upon departure), and collaborative decision-making. The IGTM concept provides effective information services and decision tools to the stakeholders, such as airline dispatchers, gate agents, airport operators, ramp controllers, and air traffic control (ATC) traffic managers and ground controllers to mitigate uncertainties arising from both nominal and off-nominal airport gate operations. IGTM will provide NAS stakeholders customized decision making tools through a User Interface (UI) by leveraging historical data (Big Data), net-enabled Air Traffic Management (ATM) live data, and analytics according to dependencies among NAS parameters for the stakeholders to manage and optimize the NAS performance in the gate turnaround domain. The application will give stakeholders predictable results based on the past and current NAS performance according to selected decision trees through the UI. The predictable results are generated based on analysis of the

  7. The role of short-time intensity and envelope power for speech intelligibility and psychoacoustic masking.

    Science.gov (United States)

    Biberger, Thomas; Ewert, Stephan D

    2017-08-01

    The generalized power spectrum model [GPSM; Biberger and Ewert (2016). J. Acoust. Soc. Am. 140, 1023-1038], combining the "classical" concept of the power-spectrum model (PSM) and the envelope power spectrum-model (EPSM), was demonstrated to account for several psychoacoustic and speech intelligibility (SI) experiments. The PSM path of the model uses long-time power signal-to-noise ratios (SNRs), while the EPSM path uses short-time envelope power SNRs. A systematic comparison of existing SI models for several spectro-temporal manipulations of speech maskers and gender combinations of target and masker speakers [Schubotz et al. (2016). J. Acoust. Soc. Am. 140, 524-540] showed the importance of short-time power features. Conversely, Jørgensen et al. [(2013). J. Acoust. Soc. Am. 134, 436-446] demonstrated a higher predictive power of short-time envelope power SNRs than power SNRs using reverberation and spectral subtraction. Here the GPSM was extended to utilize short-time power SNRs and was shown to account for all psychoacoustic and SI data of the three mentioned studies. The best processing strategy was to exclusively use either power or envelope-power SNRs, depending on the experimental task. By analyzing both domains, the suggested model might provide a useful tool for clarifying the contribution of amplitude modulation masking and energetic masking.

  8. Computation of the Short-Time Linear Canonical Transform with Dual Window

    Directory of Open Access Journals (Sweden)

    Lei Huang

    2017-01-01

    Full Text Available The short-time linear canonical transform (STLCT, which maps the time domain signal into the joint time and frequency domain, has recently attracted some attention in the area of signal processing. However, its applications are still limited due to the fact that selection of coefficients of the short-time linear canonical series (STLCS is not unique, because time and frequency elementary functions (together known as basis function of STLCS do not constitute an orthogonal basis. To solve this problem, this paper investigates a dual window solution. First, the nonorthogonal problem that suffered from original window is fulfilled by orthogonal condition with dual window. Then based on the obtained condition, a dual window computation approach of the GT is extended to the STLCS. In addition, simulations verify the validity of the proposed condition and solutions. Furthermore, some possible applied directions are discussed.

  9. Viruses as groundwater tracers: using ecohydrology to characterize short travel times in aquifers

    Science.gov (United States)

    Hunt, Randall J.; Borchardt, Mark A.; Bradbury, Kenneth R.

    2014-01-01

    Viruses are attractive tracers of short (population over time; therefore, the virus snapshot shed in the fecal wastes of an infected population at a specific point in time can serve as a marker for tracking virus and groundwater movement. The virus tracing approach and an example application are described to illustrate their ability to characterize travel times in high-groundwater velocity settings, and provide insight unavailable from standard hydrogeologic approaches. Although characterization of preferential flowpaths does not usually characterize the majority of other travel times occurring in the groundwater system (e.g., center of plume mass; tail of the breakthrough curve), virus approaches can trace very short times of transport, and thus can fill an important gap in our current hydrogeology toolbox.

  10. Energy turnaround and nuclear phaseout. Chance or meander; Energiewende und Atomausstieg. Chance oder Irrweg

    Energy Technology Data Exchange (ETDEWEB)

    Marth, Willy

    2015-07-01

    The booklet on the energy turnaround covers the following topics: ascent of the German electricity companies, early scenarios of the nuclear phase-out, the moderate energy turnaround, the controversial climatic change, Fukushima, the abrupt nuclear phase-out in Germany (2011), energy-economical problems of the abrupt energy turnaround, boom and crash of then renewable energy companies, the come-down of the German electricity companies, summary and evaluation.

  11. Turnaround and Sustainability in Economic Crisis: The Case of NEXT PLC

    OpenAIRE

    Zhang, Biyan

    2013-01-01

    Purpose- against a background of continued weak economic conditions and with many firms experiencing declining financial performance, this paper presents a synthesis of the business turnaround literature and combines with analysis case –NEXT plc. It purposes to discus the turnaround strategies can keep the declining firm sustainability recovery, during the economic cycle. \\ud \\ud Design/methodology/approach- the turnaround strategy for sustainability recovery are examined by a case study of N...

  12. Turnaround strategies: Prípadová štúdia spoločnosti Yahoo!

    OpenAIRE

    Kartalová, Petra

    2013-01-01

    This bachelor thesis focuses on Marissa Mayer's turnaround strategy in Yahoo. The thesis consists of three parts. The first part deals with the theoretical concept of a turnaround. In the second part, the whole Internet Industry Provider Industry is being analysed, as well as the main reasons that led Yahoo to fall behind the competition and lose its user base. The last part of the thesis deals with the particular turnaround strategy and its four main components -- people, products, traffic a...

  13. A Software Engineering Paradigm for Quick-turnaround Earth Science Data Projects

    Science.gov (United States)

    Moore, K.

    2016-12-01

    As is generally the case with applied sciences professional and educational programs, the participants of such programs can come from a variety of technical backgrounds. In the NASA DEVELOP National Program, the participants constitute an interdisciplinary set of backgrounds, with varying levels of experience with computer programming. DEVELOP makes use of geographically explicit data sets, and it is necessary to use geographic information systems and geospatial image processing environments. As data sets cover longer time spans and include more complex sets of parameters, automation is becoming an increasingly prevalent feature. Though platforms such as ArcGIS, ERDAS Imagine, and ENVI facilitate the batch-processing of geospatial imagery, these environments are naturally constricting to the user in that they limit him or her to the tools that are available. Users must then turn to "homemade" scripting in more traditional programming languages such as Python, JavaScript, or R, to automate workflows. However, in the context of quick-turnaround projects like those in DEVELOP, the programming learning curve may be prohibitively steep. In this work, we consider how to best design a software development paradigm that addresses two major constants: an arbitrarily experienced programmer and quick-turnaround project timelines.

  14. Corrections for the combined effects of decay and dead time in live-timed counting of short-lived radionuclides

    International Nuclear Information System (INIS)

    Fitzgerald, R.

    2016-01-01

    Studies and calibrations of short-lived radionuclides, for example "1"5O, are of particular interest in nuclear medicine. Yet counting experiments on such species are vulnerable to an error due to the combined effect of decay and dead time. Separate decay corrections and dead-time corrections do not account for this issue. Usually counting data are decay-corrected to the start time of the count period, or else instead of correcting the count rate, the mid-time of the measurement is used as the reference time. Correction factors are derived for both those methods, considering both extending and non-extending dead time. Series approximations are derived here and the accuracy of those approximations are discussed. - Highlights: • Derived combined effects of decay and dead time. • Derived for counting systems with extending or non-extending dead times. • Derived series expansions for both midpoint and decay-to-start-time methods. • Useful for counting experiments with short-lived radionuclides. • Examples given for "1"5O, used in PET scanning.

  15. NMR transmit-receive system with short recovery time and effective isolation

    Science.gov (United States)

    Jurga, K.; Reynhardt, E. C.; Jurga, S.

    A transmit-receive system with a short recovery time and excellent isolation has been developed. The system operates in conjunction with an ENI Model 3200L broadband amplifier and a spin-lock NMR pulse spectrometer. The system has been tested in the frequency range 5.5 to 52 MHz and seems not to generate any background noise.

  16. A Unified Framework for Estimating Minimum Detectable Effects for Comparative Short Interrupted Time Series Designs

    Science.gov (United States)

    Price, Cristofer; Unlu, Fatih

    2014-01-01

    The Comparative Short Interrupted Time Series (C-SITS) design is a frequently employed quasi-experimental method, in which the pre- and post-intervention changes observed in the outcome levels of a treatment group is compared with those of a comparison group where the difference between the former and the latter is attributed to the treatment. The…

  17. Eulerian short-time statistics of turbulent flow at large Reynolds number

    NARCIS (Netherlands)

    Brouwers, J.J.H.

    2004-01-01

    An asymptotic analysis is presented of the short-time behavior of second-order temporal velocity structure functions and Eulerian acceleration correlations in a frame that moves with the local mean velocity of the turbulent flow field. Expressions in closed-form are derived which cover the viscous

  18. Modular High Voltage Pulse Converter for Short Rise and Decay Times

    NARCIS (Netherlands)

    Mao, S.

    2018-01-01

    This thesis explores a modular HV pulse converter technology with short rise and decay times. A systematic methodology to derive and classify HV architectures based on a modularization level of power building blocks of the HV pulse converter is developed to summarize existing architectures and

  19. Extracting biologically significant patterns from short time series gene expression data

    Directory of Open Access Journals (Sweden)

    McGinnis Thomas

    2009-08-01

    Full Text Available Abstract Background Time series gene expression data analysis is used widely to study the dynamics of various cell processes. Most of the time series data available today consist of few time points only, thus making the application of standard clustering techniques difficult. Results We developed two new algorithms that are capable of extracting biological patterns from short time point series gene expression data. The two algorithms, ASTRO and MiMeSR, are inspired by the rank order preserving framework and the minimum mean squared residue approach, respectively. However, ASTRO and MiMeSR differ from previous approaches in that they take advantage of the relatively few number of time points in order to reduce the problem from NP-hard to linear. Tested on well-defined short time expression data, we found that our approaches are robust to noise, as well as to random patterns, and that they can correctly detect the temporal expression profile of relevant functional categories. Evaluation of our methods was performed using Gene Ontology (GO annotations and chromatin immunoprecipitation (ChIP-chip data. Conclusion Our approaches generally outperform both standard clustering algorithms and algorithms designed specifically for clustering of short time series gene expression data. Both algorithms are available at http://www.benoslab.pitt.edu/astro/.

  20. X-ray testing for short-time dynamic applications; Roentgenuntersuchungen fuer kurzzeitdynamische Anwendungen

    Energy Technology Data Exchange (ETDEWEB)

    Kurfiss, Malte; Moser, Stefan; Popko, Gregor; Nau, Siegfried [Fraunhofer-Institut fuer Kurzzeitdynamik, Efringen-Kirchen (Germany). Ernst-Mach-Inst. (EMI)

    2017-08-01

    For nondestructive testing purposes new challenges are short-time dynamic processes. The application of x-ray flash tubes and modern high-speed cameras allows the observation of the opening of air-bags or the energy absorption of compressed tubes as occurring during a vehicle crash. Special algorithms designed for computerized tomography analyses allow the 3D reconstruction at individual time points of the dynamic process. Possibilities and limitations of the actual techniques are discussed.

  1. Rotor-System Log-Decrement Identification Using Short-Time Fourier-Transform Filter

    OpenAIRE

    Li, Qihang; Wang, Weimin; Chen, Lifang; Sun, Dan

    2015-01-01

    With the increase of the centrifugal compressor capability, such as large scale LNG and CO2 reinjection, the stability margin evaluation is crucial to assure the compressor work in the designed operating conditions in field. Improving the precision of parameter identification of stability is essential and necessary as well. Based on the time-varying characteristics of response vibration during the sine-swept process, a short-time Fourier transform (STFT) filter was introduced to increase the ...

  2. Spectrogram analysis of selected tremor signals using short-time Fourier transform and continuous wavelet transform

    Energy Technology Data Exchange (ETDEWEB)

    Bartosch, T. [Erlanger-Nuernberg Univ., Erlanger (Germany). Lehrstul fuer Nachrichtentechnik I; Seidl, D. [Seismologisches Zentralobservatorium Graefenberg, Erlanegen (Greece). Bundesanstalt fuer Geiwissenschaften und Rohstoffe

    1999-06-01

    Among a variety of spectrogram methods short-time Fourier transform (STFT) and continuous wavelet transform (CWT) were selected to analyse transients in non-stationary signals. Depending on the properties of the tremor signals from the volcanos Mt. Stromboli, Mt. Semeru and Mt. Pinatubo were analyzed using both methods. The CWT can also be used to extend the definition of coherency into a time-varying coherency spectrogram. An example is given using array data from the volcano Mt. Stromboli (Italy).

  3. Into the black. 1993 Hospital Turnaround Contest winners.

    Science.gov (United States)

    Cerne, F; Bergman, R

    1993-07-20

    Turning a hospital around takes a lot more than adjusting the financials, as the winners and finalists in the Great Comebacks 1993: The Hospital Turnaround Contest demonstrate. In every case we report on, the hospital being recognized has worked intensively with its community to reassess the services needed by its patients, build support for major management and delivery changes, and articulate the reasons for the strategies being used. Each of the eight hospital organizations we profile, which are spread across the country from Texas to Wisconsin to Maine to North Carolina--has put together its own version of success--in other words, eight lessons in innovation and progress.

  4. Meeting the challenge of a group practice turnaround.

    Science.gov (United States)

    Porn, L M

    2001-03-01

    Many healthcare organizations that acquired group practices to enhance their market share have found that the practices have not met their financial goals. Turning around a financially troubled, hospital-owned group practice is challenging but not impossible for healthcare organizations that take certain basic actions. Direction, data, desire, dedication, and drive must be present to effect the financial turnaround of a group practice. The healthcare organization needs to evaluate the practice's strategy and operations and identify the issues that are hindering the practice's ability to optimize revenues. Efforts to achieve profitable operations have to be ongoing.

  5. The effect of long and short time oil shocks on economic growth in Iran

    OpenAIRE

    Sayyed Abdolmajid Jalae; Sanaz Mohammadi

    2012-01-01

    Oil is one of the strategic good so that price fluctuations and shocks of it have major effects on economic growth and recession in depended countries to revenues of it. In this study, it is tried that the effect of oil price shocks investigated in two types (short and long time) on Economic growth in Iran. Its Period is from 1974 to 2006. According it, oil price uncertainty is quantized by GARCH model and is determined the effects of oil price shocks on economic growth in Iran during a short...

  6. Investing for Sustainable Turnaround. Sustaining School Turnaround at Scale. Brief 2

    Science.gov (United States)

    Education Resource Strategies, 2012

    2012-01-01

    The Federal government has brought the issue of low-performing schools to the forefront of public conversation by committing $3.5 billion over three years to turn around these schools. As of March 2011, over 1200 schools across the country had been awarded School Improvement Grants (SIG). Given the magnitude of this short-term investment and the…

  7. The time of onset of abnormal calcification in spondylometaepiphyseal dysplasia, short limb-abnormal calcification type

    Energy Technology Data Exchange (ETDEWEB)

    Tueysuez, Beyhan [Istanbul University, Department of Pediatric Genetics, Cerrahpasa Medical School, Istanbul (Turkey); Gazioglu, Nurperi [Istanbul University, Department of Neurosurgery, Cerrahpasa Medical School, Istanbul (Turkey); Uenguer, Savas [Istanbul University, Department of Pediatric Radiology, Cerrahpasa Medical School, Istanbul (Turkey); Aji, Dolly Yafet [Istanbul University, Department of Pediatrics, Cerrahpasa Medical School, Istanbul (Turkey); Tuerkmen, Seval [Istanbul University, Department of Pediatric Genetics, Cerrahpasa Medical School, Istanbul (Turkey); Universitatsklinikum Berlin, Charite Virchow-Klinik, Berlin (Germany)

    2009-01-15

    A 1-month-old boy with shortness of extremities on prenatal US was referred to our department with a provisional diagnosis of achondroplasia. His height was normal but he had short extremities and platyspondyly, premature carpal epiphyses on both hands, and short tubular bones with irregular metaphyses on radiographs. Re-evaluation of the patient at the age of 1 year revealed very short height and premature calcification of the costal cartilages and epiphyses. Spondylometaepiphyseal dysplasia (SMED), short limb-abnormal calcification type was diagnosed. This condition is a very rare autosomal recessively inherited disorder, and most of the patients die in early childhood due to neurological involvement. At the age of 2 years and 5 months, a CT scan showed narrowing of the cervical spinal canal. One month later he died suddenly because of spinal cord injury. In conclusion early diagnosis is very important because the recurrence risk is high and patients may die due to early neurological complications. The time of onset of abnormal calcifications, a diagnostic finding of the disease, is at the age of around 1 year in most patients. When abnormal calcifications are not yet present, but radiological changes associated with SMED are present, this rare disease must be considered. (orig.)

  8. The time of onset of abnormal calcification in spondylometaepiphyseal dysplasia, short limb-abnormal calcification type

    International Nuclear Information System (INIS)

    Tueysuez, Beyhan; Gazioglu, Nurperi; Uenguer, Savas; Aji, Dolly Yafet; Tuerkmen, Seval

    2009-01-01

    A 1-month-old boy with shortness of extremities on prenatal US was referred to our department with a provisional diagnosis of achondroplasia. His height was normal but he had short extremities and platyspondyly, premature carpal epiphyses on both hands, and short tubular bones with irregular metaphyses on radiographs. Re-evaluation of the patient at the age of 1 year revealed very short height and premature calcification of the costal cartilages and epiphyses. Spondylometaepiphyseal dysplasia (SMED), short limb-abnormal calcification type was diagnosed. This condition is a very rare autosomal recessively inherited disorder, and most of the patients die in early childhood due to neurological involvement. At the age of 2 years and 5 months, a CT scan showed narrowing of the cervical spinal canal. One month later he died suddenly because of spinal cord injury. In conclusion early diagnosis is very important because the recurrence risk is high and patients may die due to early neurological complications. The time of onset of abnormal calcifications, a diagnostic finding of the disease, is at the age of around 1 year in most patients. When abnormal calcifications are not yet present, but radiological changes associated with SMED are present, this rare disease must be considered. (orig.)

  9. Short time propagation of a singular wave function: Some surprising results

    Science.gov (United States)

    Marchewka, A.; Granot, E.; Schuss, Z.

    2007-08-01

    The Schrödinger evolution of an initially singular wave function was investigated. First it was shown that a wide range of physical problems can be described by initially singular wave function. Then it was demonstrated that outside the support of the initial wave function the time evolution is governed to leading order by the values of the wave function and its derivatives at the singular points. Short-time universality appears where it depends only on a single parameter—the value at the singular point (not even on its derivatives). It was also demonstrated that the short-time evolution in the presence of an absorptive potential is different than in the presence of a nonabsorptive one. Therefore, this dynamics can be harnessed to the determination whether a potential is absorptive or not simply by measuring only the transmitted particles density.

  10. Flow characteristics of a pilot-scale high temperature, short time pasteurizer.

    Science.gov (United States)

    Tomasula, P M; Kozempel, M F

    2004-09-01

    In this study, we present a method for determining the fastest moving particle (FMP) and residence time distribution (RTD) in a pilot-scale high temperature, short time (HTST) pasteurizer to ensure that laboratory or pilot-scale HTST apparatus meets the Pasteurized Milk Ordinance standards for pasteurization of milk and can be used for obtaining thermal inactivation data. The overall dimensions of the plate in the pasteurizer were 75 x 115 mm, with a thickness of 0.5 mm and effective diameter of 3.0 mm. The pasteurizer was equipped with nominal 21.5- and 52.2-s hold tubes, and flow capacity was variable from 0 to 20 L/h. Tracer studies were used to determine FMP times and RTD data to establish flow characteristics. Using brine milk as tracer, the FMP time for the short holding section was 18.6 s and for the long holding section was 36 s at 72 degrees C, compared with the nominal times of 21.5 and 52.2 s, respectively. The RTD study indicates that the short hold section was 45% back mixed and 55% plug flow for whole milk at 72 degrees C. The long hold section was 91% plug and 9% back mixed for whole milk at 72 degrees C. This study demonstrates that continuous laboratory and pilot-scale pasteurizers may be used to study inactivation of microorganisms only if the flow conditions in the holding tube are established for comparison with commercial HTST systems.

  11. Difference-based clustering of short time-course microarray data with replicates

    Directory of Open Access Journals (Sweden)

    Kim Jihoon

    2007-07-01

    Full Text Available Abstract Background There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain knowledge and do not incorporate information from replicates. Moreover, the results are not always easy to interpret biologically. Results We propose a novel algorithm for identifying a subset of genes sharing a significant temporal expression pattern when replicates are used. Our algorithm requires no prior knowledge, instead relying on an observed statistic which is based on the first and second order differences between adjacent time-points. Here, a pattern is predefined as the sequence of symbols indicating direction and the rate of change between time-points, and each gene is assigned to a cluster whose members share a similar pattern. We evaluated the performance of our algorithm to those of K-means, Self-Organizing Map and the Short Time-series Expression Miner methods. Conclusions Assessments using simulated and real data show that our method outperformed aforementioned algorithms. Our approach is an appropriate solution for clustering short time-course microarray data with replicates.

  12. Dimension reduction of frequency-based direct Granger causality measures on short time series.

    Science.gov (United States)

    Siggiridou, Elsa; Kimiskidis, Vasilios K; Kugiumtzis, Dimitris

    2017-09-01

    The mainstream in the estimation of effective brain connectivity relies on Granger causality measures in the frequency domain. If the measure is meant to capture direct causal effects accounting for the presence of other observed variables, as in multi-channel electroencephalograms (EEG), typically the fit of a vector autoregressive (VAR) model on the multivariate time series is required. For short time series of many variables, the estimation of VAR may not be stable requiring dimension reduction resulting in restricted or sparse VAR models. The restricted VAR obtained by the modified backward-in-time selection method (mBTS) is adapted to the generalized partial directed coherence (GPDC), termed restricted GPDC (RGPDC). Dimension reduction on other frequency based measures, such the direct directed transfer function (dDTF), is straightforward. First, a simulation study using linear stochastic multivariate systems is conducted and RGPDC is favorably compared to GPDC on short time series in terms of sensitivity and specificity. Then the two measures are tested for their ability to detect changes in brain connectivity during an epileptiform discharge (ED) from multi-channel scalp EEG. It is shown that RGPDC identifies better than GPDC the connectivity structure of the simulated systems, as well as changes in the brain connectivity, and is less dependent on the free parameter of VAR order. The proposed dimension reduction in frequency measures based on VAR constitutes an appropriate strategy to estimate reliably brain networks within short-time windows. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Fast Aircraft Turnaround Enabled by Reliable Passenger Boarding

    Directory of Open Access Journals (Sweden)

    Michael Schultz

    2018-01-01

    Full Text Available Future 4D aircraft trajectories demand comprehensive consideration of environmental, economic, and operational constraints, as well as reliable prediction of all aircraft-related processes. Mutual interdependencies between airports result in system-wide, far-reaching effects in the air traffic network (reactionary delays. To comply with airline/airport challenges over the day of operations, a change to an air-to-air perspective is necessary, with a specific focus on the aircraft ground operations as major driver for airline punctuality. Aircraft ground trajectories primarily consists of handling processes at the stand (deboarding, catering, fueling, cleaning, boarding, unloading, loading, which are defined as the aircraft turnaround. Turnaround processes are mainly controlled by ground handling, airport, or airline staff, except the aircraft boarding, which is driven by passengers’ experience and willingness/ability to follow the proposed boarding procedures. This paper provides an overview of the research done in the field of aircraft boarding and introduces a reliable, calibrated, and stochastic aircraft boarding model. The stochastic boarding model is implemented in a simulation environment to evaluate specific boarding scenarios using different boarding strategies and innovative technologies. Furthermore, the potential of a connected aircraft cabin as sensor network is emphasized, which could provide information on the current and future status of the boarding process.

  14. Short irradiation time characteristics of the inverter type X-ray generator

    International Nuclear Information System (INIS)

    Miyazaki, Shigeru; Hara, Takamitu; Matutani, Kazuo; Saito, Kazuhiko.

    1994-01-01

    The linearity of the X-ray output is an important factor in radiography. It is a composite of the linearities of the X-ray tube voltage, the X-ray tube current, and the exposure time. This paper focuses on the linearity of exposure time. Non-linearity of the X-ray output for short-time exposure became a problem when the three-phase X-ray generator was introduced. This paper describes the inverter-type X-ray generator, which is expected to become predominant in the future. Previously, we investigated X-ray output linearity during short-time exposure using the technique of dynamic study. In this paper, we describe the application of a digital memory and a personal computer to further investigation. The non-linearity of the X-ray output was caused by irregular waveforms of the X-ray tube voltage found at the rise time and the fall time. When the rise time was about 0.6 ms, the non-linearity was about 2%, which is negligibly small. The non-linearity due to the fall time of the X-ray tube varied greatly according to the X-ray tube current. For the minimum irradiation time of 1 ms, 4% to 27% of the non-linearity was attributable to the fall time. The main cause was the stray capacitance of the X-ray high-voltage cables. When the X-ray tube current exceeded 400 mA, the rise time was almost equal to the fall time, and the problem did not occur. Consequently, the ideal generator should have a fall time which is equal to the rise time of the X-ray tube voltage. Strictly speaking, such a generator should have rectangular waveforms. (author)

  15. Short-time existence of solutions for mean-field games with congestion

    KAUST Repository

    Gomes, Diogo A.

    2015-11-20

    We consider time-dependent mean-field games with congestion that are given by a Hamilton–Jacobi equation coupled with a Fokker–Planck equation. These models are motivated by crowd dynamics in which agents have difficulty moving in high-density areas. The congestion effects make the Hamilton–Jacobi equation singular. The uniqueness of solutions for this problem is well understood; however, the existence of classical solutions was only known in very special cases, stationary problems with quadratic Hamiltonians and some time-dependent explicit examples. Here, we demonstrate the short-time existence of C∞ solutions for sub-quadratic Hamiltonians.

  16. Spectral phase encoding of ultra-short optical pulse in time domain for OCDMA application.

    Science.gov (United States)

    Wang, Xu; Wada, Naoya

    2007-06-11

    We propose a novel reconfigurable time domain spectral phase encoding (SPE) scheme for coherent optical code-division-multiple-access application. In the proposed scheme, the ultra-short optical pulse is stretched by dispersive device and the SPE is done in time domain using high speed phase modulator. The time domain SPE scheme is robust to wavelength drift of the light source and is very flexible and compatible with the fiber optical system. Proof-of-principle experiments of encoding with 16-chip, 20 GHz/chip binary-phase-shift-keying codes and 1.25 Gbps data transmission have been successfully demonstrated together with an arrayed-wave-guide decoder.

  17. Short-time maximum entropy method analysis of molecular dynamics simulation: Unimolecular decomposition of formic acid

    Science.gov (United States)

    Takahashi, Osamu; Nomura, Tetsuo; Tabayashi, Kiyohiko; Yamasaki, Katsuyoshi

    2008-07-01

    We performed spectral analysis by using the maximum entropy method instead of the traditional Fourier transform technique to investigate the short-time behavior in molecular systems, such as the energy transfer between vibrational modes and chemical reactions. This procedure was applied to direct ab initio molecular dynamics calculations for the decomposition of formic acid. More reactive trajectories of dehydrolation than those of decarboxylation were obtained for Z-formic acid, which was consistent with the prediction of previous theoretical and experimental studies. Short-time maximum entropy method analyses were performed for typical reactive and non-reactive trajectories. Spectrograms of a reactive trajectory were obtained; these clearly showed the reactant, transient, and product regions, especially for the dehydrolation path.

  18. New serial time codes for seismic short period and long period data acquisition systems

    International Nuclear Information System (INIS)

    Kolvankar, V.G.; Rao, D.S.

    1988-01-01

    This paper discusses a new time code for time indexing multichannel short period (1 to 25 hz) seismic event data recorded on a single track of magnetic tape in digital format and discusses its usefulness in contrast to Vela time code used in continuous analog multichannel data recording system on multitrack instrumentation tape deck. This paper also discusses another time code, used for time indexing of seismic long period (DC to 2.5 seconds) multichannel data recorded on a single track of magnetic tape in digital format. The time code decoding and display system developed to provide quick access to any desired portion of the tape in both data recording and repro duce system is also discussed. (author). 7 figs

  19. Optimization of irradiation decay and counting times in nuclear activation analysis using short-lived nuclides

    International Nuclear Information System (INIS)

    Bjoernstad, T.

    This work describes a method and outlines a procedure for optim- ization of an activation analysis with respect to the experimental times, irradiation time, t(subi), decay time and counting time. The method is based on the 'minimum relative standard deviation criterion', and specially designed for the use on short-lived nuclides. A computer program, COMB1, is written in the BASIC language in order to make the calculations easier and faster. It is intended to be understandable, and easily applicable on a computer of modest size. Time and cost are important factors, especially for routine analysis on a service basis. In such cases one can often allow a controlled reduction in the analysis quality (through a higher relative standard deviation). The procedure outlined can therefore help find acceptable conditions by calculation of the 'best practical' (or reasonable) experimental time values, and the minimum number of accumulation cycles necessary to fulfil the requirements given. (Auth.)

  20. Short-Term Memory Loss Over Time Without Retroactive Stimulus Interference

    OpenAIRE

    Cowan, Nelson; AuBuchon, Angela M.

    2008-01-01

    A key question in cognitive psychology is whether information in short-term memory is lost as a function of time. Lewandowsky, Duncan, and Brown (2004) argued against that memory loss because forgetting in serial recall occurred to the same extent across serial positions regardless of the rate of recall. However, we believe Lewandowsky et al. only prevented one of two types of rehearsal; they did not prevent non-articulatory rehearsal via attention. To prevent articulatory and non-articulator...

  1. Thermonuclear Bursts with Short Recurrence Times from Neutron Stars Explained by Opacity-driven Convection

    Energy Technology Data Exchange (ETDEWEB)

    Keek, L. [X-ray Astrophysics Laboratory, Astrophysics Science Division, NASA/GSFC, Greenbelt, MD 20771 (United States); Heger, A., E-mail: laurens.keek@nasa.gov [Monash Center for Astrophysics, School of Physics and Astronomy, Monash University, Victoria, 3800 (Australia)

    2017-06-20

    Thermonuclear flashes of hydrogen and helium accreted onto neutron stars produce the frequently observed Type I X-ray bursts. It is the current paradigm that almost all material burns in a burst, after which it takes hours to accumulate fresh fuel for the next burst. In rare cases, however, bursts are observed with recurrence times as short as minutes. We present the first one-dimensional multi-zone simulations that reproduce this phenomenon. Bursts that ignite in a relatively hot neutron star envelope leave a substantial fraction of the fuel unburned at shallow depths. In the wake of the burst, convective mixing events driven by opacity bring this fuel down to the ignition depth on the observed timescale of minutes. There, unburned hydrogen mixes with the metal-rich ashes, igniting to produce a subsequent burst. We find burst pairs and triplets, similar to the observed instances. Our simulations reproduce the observed fraction of bursts with short waiting times of ∼30%, and demonstrate that short recurrence time bursts are typically less bright and of shorter duration.

  2. A qualitative investigation on the successful turnaround strategy from top leader perspectives: examples from Indonesia

    Directory of Open Access Journals (Sweden)

    Yulihasri

    2018-06-01

    Full Text Available Turnaround process involved many approaches of strategic and tactical attempts. However, such knowledge are difficult to identified since many previous studies only focused on what constitute successful turnaround, and limited to the use of financial data. As turnaround is a transformational process comprehend every element of organization, ploy on implementing and orchestrating such strategic action should be determined by company’s top leaders. The purpose of this study was to explore the way in which leaders manage the company’s turnaround process and their leadership style through a qualitative study in Indonesian business. Drawing from several top managers in various industry in Indonesia, the result showed that there are many attempt should consider on implementing turnaround process. Financial restructuration, employee’s transformation initiative, and business reengineering process are imperative approaches. Furthermore, leaders need to consider top-down approach on decision making, attention to detail, and open communication to gain employees commitment.

  3. TRACnet Internet and Short Message Service Technology Improves Time to Antiretroviral Therapy Initiation Among HIV-infected Infants in Rwanda.

    Science.gov (United States)

    Kayumba, Kizito; Nsanzimana, Sabin; Binagwaho, Agnes; Mugwaneza, Placidie; Rusine, John; Remera, Eric; Koama, Jean Baptiste; Ndahindwa, Vedaste; Johnson, Pamela; Riedel, David J; Condo, Jeanine

    2016-07-01

    Delays in testing HIV-exposed infants and obtaining results in resource-limited settings contribute to delays for initiating antiretroviral therapy (ART) in infants. To overcome this challenge, Rwanda expanded its national mobile and Internet-based HIV/AIDS informatics system, called TRACnet, to include HIV polymerase chain reaction (PCR) results in 2010. This study was performed to evaluate the impact of TRACnet technology on the time to delivery of test results and the subsequent initiation of ART in HIV-infected infants. A retrospective cohort study was conducted on 380 infants who initiated ART in 190 health facilities in Rwanda from March 2010 to June 2013. Program data collected by the TRACnet system were extracted and analyzed. Since the introduction of TRACnet for processing PCR results, the time to receive results has significantly decreased from a median of 144 days [interquartile range (IQR): 121-197 days] to 23 days (IQR: 17-43 days). The number of days between PCR sampling and health facility receipt of results decreased substantially from a median of 90 days (IQR: 83-158 days) to 5 days (IQR: 2-8 days). After receiving PCR results at a health facility, it takes a median of 44 days (IQR: 32-77 days) before ART initiation. Result turnaround time was significantly associated with time to initiating ART (P technology for communication of HIV PCR results, coupled with well-trained and skilled personnel, can reduce delays in communicating results to providers. Such reductions may improve timely ART initiation in resource-limited settings.

  4. Quantifying complexity of financial short-term time series by composite multiscale entropy measure

    Science.gov (United States)

    Niu, Hongli; Wang, Jun

    2015-05-01

    It is significant to study the complexity of financial time series since the financial market is a complex evolved dynamic system. Multiscale entropy is a prevailing method used to quantify the complexity of a time series. Due to its less reliability of entropy estimation for short-term time series at large time scales, a modification method, the composite multiscale entropy, is applied to the financial market. To qualify its effectiveness, its applications in the synthetic white noise and 1 / f noise with different data lengths are reproduced first in the present paper. Then it is introduced for the first time to make a reliability test with two Chinese stock indices. After conducting on short-time return series, the CMSE method shows the advantages in reducing deviations of entropy estimation and demonstrates more stable and reliable results when compared with the conventional MSE algorithm. Finally, the composite multiscale entropy of six important stock indices from the world financial markets is investigated, and some useful and interesting empirical results are obtained.

  5. Time-frequency analysis of fusion plasma signals beyond the short-time Fourier transform paradigm: An overview

    International Nuclear Information System (INIS)

    Bizarro, Joao P.S.; Figueiredo, Antonio C.A.

    2008-01-01

    Performing a time-frequency (t-f) analysis on actual magnetic pick-up coil data from the JET tokamak, a comparison is presented between the spectrogram and the Wigner and Choi-Williams distributions. Whereas the former, which stems from the short-time Fourier transform and has been the work-horse for t-f signal processing, implies an unavoidable trade-off between time and frequency resolutions, the latter two belong to a later generation of distributions that yield better, if not optimal joint t-f localization. Topics addressed include signal representation in the t-f plane, frequency identification and evolution, instantaneous-frequency estimation, and amplitude tracking

  6. Short-Term Change Detection in Wetlands Using Sentinel-1 Time Series

    DEFF Research Database (Denmark)

    Muro, Javier; Canty, Morton; Conradsen, Knut

    2016-01-01

    Automated monitoring systems that can capture wetlands’ high spatial and temporal variability are essential for their management. SAR-based change detection approaches offer a great opportunity to enhance our understanding of complex and dynamic ecosystems. We test a recently-developed time serie...... certain landscape changes are detected only by either the Landsat-based or the S1-omnibus method. The S1-omnibus method shows a great potential for an automated monitoring of short time changes and accurate delineation of areas of high variability and of slow and gradual changes....

  7. Identification of the structure parameters using short-time non-stationary stochastic excitation

    Science.gov (United States)

    Jarczewska, Kamila; Koszela, Piotr; Śniady, PaweŁ; Korzec, Aleksandra

    2011-07-01

    In this paper, we propose an approach to the flexural stiffness or eigenvalue frequency identification of a linear structure using a non-stationary stochastic excitation process. The idea of the proposed approach lies within time domain input-output methods. The proposed method is based on transforming the dynamical problem into a static one by integrating the input and the output signals. The output signal is the structure reaction, i.e. structure displacements due to the short-time, irregular load of random type. The systems with single and multiple degrees of freedom, as well as continuous systems are considered.

  8. Performance evaluation of the short-time objective intelligibility measure with different band importance functions

    DEFF Research Database (Denmark)

    Heidemann Andersen, Asger; de Haan, Jan Mark; Tan, Zheng-Hua

    performance measures: root-mean-squared-error, Pearson correlation, and Kendall rank correlation. The results show substantially improved performance when fitting and evaluating on the same dataset. However, this advantage does not necessarily subsist when fitting and evaluating on different datasets. When...... with a filter bank, 2) envelopes are extracted from each band, 3) the temporal correlation between clean and degraded envelopes is computed in short time segments, and 4) the correlation is averaged across time and frequency bands to obtain the final output. An unusual choice in the design of the STOI measure...

  9. Spectrogram analysis of selected tremor signals using short-time Fourier transform and continuous wavelet transform

    Directory of Open Access Journals (Sweden)

    D. Seidl

    1999-06-01

    Full Text Available Among a variety of spectrogram methods Short-Time Fourier Transform (STFT and Continuous Wavelet Transform (CWT were selected to analyse transients in non-stationary tremor signals. Depending on the properties of the tremor signal a more suitable representation of the signal is gained by CWT. Three selected broadband tremor signals from the volcanos Mt. Stromboli, Mt. Semeru and Mt. Pinatubo were analyzed using both methods. The CWT can also be used to extend the definition of coherency into a time-varying coherency spectrogram. An example is given using array data from the volcano Mt. Stromboli.

  10. Automated Detection of Short Optical Transients of Astrophysical Origin in Real Time

    Directory of Open Access Journals (Sweden)

    Marcin Sokołowski

    2010-01-01

    Full Text Available The detection of short optical transients of astrophysical origin in real time is an important task for existing robotic telescopes. The faster a new optical transient is detected, the earlier follow-up observations can be started. The sooner the object is identified, the more data can be collected before the source fades away, particularly in the most interesting early period of the transient. In this the real-time pipeline designed for identification of optical flashes with the “Pi of the Sky” project will be presented in detail together with solutions used by other experiments.

  11. A characterization of persistence at short times in the WFC3/IR detector

    Science.gov (United States)

    Gennaro, M.; Bajaj, V.; Long, K.

    2018-05-01

    Persistence in the WFC3/IR detector appears to decay as a power law as a function of time elapsed since the end of a stimulus. In this report we study departures from the power law at times shorter than a few hundreds seconds after the stimulus. In order to have better short-time cadence, we use the Multiaccum (.ima) files, which trace the accumulated charge in the pixels as function of time, rather than the final pipeline products (.flt files), which instead report the electron rate estimated via a linear fit to the accumulated charge vs. time relation. We note that at short times after the stimulus, the absolute change in persistence is the strongest, thus a linear fit to the accumulated signal (the .flt values) can be a poor representation of the strongly varying persistence signal. The already observed power-law decay of the persistence signal, still holds at shorter times, with typical values of the power law index, gamma in [-0.8,-1] for stimuli that saturate the WFC3 pixels. To a good degree of approximation, a single power law is a good fit to the persistence signal decay from 100 to 5000 seconds. We also detect a tapering-off in the power-law decay at increasingly shorter times. This change in behavior is of the order of Delta Gamma 0.02 - 0.05 when comparing power-law fits performed to the persistence signal from 0 up to 250 seconds and from 0 up to 4000 seconds after the stimulus, indicating that persistence decays slightly more rapidly as time progresses. Our results may suggest that for even shorter times, not probed by our study, the WFC3 persistence signal might deviate from a single power-law model.

  12. Turnaround strategies for companies in crisis: Watch out the causes of decline before firing people

    Directory of Open Access Journals (Sweden)

    Monica Santana

    2017-07-01

    Full Text Available When a company goes into crisis, the first and most typical response is the dismissal of people, even before considering the sources of the decline. Although the reduction of costs may seem a quick and reasonable measure in this context, downsizing is not the only possibility, nor the most advisable response when facing decline. In turn, by identifying and understanding the sources of decline in time, a company may want to decide on human resource (HR alternatives to layoffs. This research shows how the HR responses of declining companies should be in line with the sources of the decline. Adopting a configurational perspective, we propose a model of analysis that links sources of decline, turnaround strategy, and HR strategy (HRS and practices. This model identifies four basic HRS for organizations in decline, according to its sources: flexibility-oriented, efficiency-oriented, niche-oriented, and maintenance-oriented HRS.

  13. Adaptive synchrosqueezing based on a quilted short-time Fourier transform

    Science.gov (United States)

    Berrian, Alexander; Saito, Naoki

    2017-08-01

    In recent years, the synchrosqueezing transform (SST) has gained popularity as a method for the analysis of signals that can be broken down into multiple components determined by instantaneous amplitudes and phases. One such version of SST, based on the short-time Fourier transform (STFT), enables the sharpening of instantaneous frequency (IF) information derived from the STFT, as well as the separation of amplitude-phase components corresponding to distinct IF curves. However, this SST is limited by the time-frequency resolution of the underlying window function, and may not resolve signals exhibiting diverse time-frequency behaviors with sufficient accuracy. In this work, we develop a framework for an SST based on a "quilted" short-time Fourier transform (SST-QSTFT), which allows adaptation to signal behavior in separate time-frequency regions through the use of multiple windows. This motivates us to introduce a discrete reassignment frequency formula based on a finite difference of the phase spectrum, ensuring computational accuracy for a wider variety of windows. We develop a theoretical framework for the SST-QSTFT in both the continuous and the discrete settings, and describe an algorithm for the automatic selection of optimal windows depending on the region of interest. Using synthetic data, we demonstrate the superior numerical performance of SST-QSTFT relative to other SST methods in a noisy context. Finally, we apply SST-QSTFT to audio recordings of animal calls to demonstrate the potential of our method for the analysis of real bioacoustic signals.

  14. The loss of short-term visual representations over time: decay or temporal distinctiveness?

    Science.gov (United States)

    Mercer, Tom

    2014-12-01

    There has been much recent interest in the loss of visual short-term memories over the passage of time. According to decay theory, visual representations are gradually forgotten as time passes, reflecting a slow and steady distortion of the memory trace. However, this is controversial and decay effects can be explained in other ways. The present experiment aimed to reexamine the maintenance and loss of visual information over the short term. Decay and temporal distinctiveness models were tested using a delayed discrimination task, in which participants compared complex and novel objects over unfilled retention intervals of variable length. Experiment 1 found no significant change in the accuracy of visual memory from 2 to 6 s, but the gap separating trials reliably influenced task performance. Experiment 2 found evidence for information loss at a 10-s retention interval, but temporally separating trials restored the fidelity of visual memory, possibly because temporally isolated representations are distinct from older memory traces. In conclusion, visual representations lose accuracy at some point after 6 s, but only within temporally crowded contexts. These findings highlight the importance of temporal distinctiveness within visual short-term memory. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  15. [Clinical characteristics of short tear film breakup time (BUT) -type dry eye].

    Science.gov (United States)

    Yamamoto, Yuji; Yokoi, Norihiko; Higashihara, Hisayo; Inagaki, Kayoko; Sonomura, Yukiko; Komuro, Aoi; Kinoshita, Shigeru

    2012-12-01

    To evaluate the clinical characteristics and management of short tear film breakup time (BUT) -type dry eye. Clinical background and post-treatment changes of symptoms in 77 patients with short BUT -type dry eye were investigated. Treatment consisted of artificial-tear eye-drop instillation and, if necessary, the addition of a low-density-level steroid, hyaluronic acid, a low-density-level cyclopentolate prepared by ourselves and punctal plugs inserted into the upper and lower lacrimal puncta. There were three times more women than men among the patients, and the peak age of occurrence was in the twenties in the men and in the sixties in the women. Our findings show that visual display terminal (VDT) work, contact lens (CL) wear, and changes in the sex hormones may initiate subjective symptoms. Some patients had simultaneous conjunctivochalasis, allergic conjunctivitis, and meibomian gland dysfunction. Nineteen patients (24.7%) were effectively treated with eye-drop instillation alone. Thirty-seven patients (48.1%) required punctal-plug insertion, which was completely effective in only 8 of them (21.6%). Mainly young men and menopausal women contract short BUT -type dry eye. Changes in sex hormones, VDT work and CL wear may be causal, and the disease cannot be controlled by eyedrop and punctal-plug treatment alone.

  16. Research on resistance characteristics of YBCO tape under short-time DC large current impact

    Science.gov (United States)

    Zhang, Zhifeng; Yang, Jiabin; Qiu, Qingquan; Zhang, Guomin; Lin, Liangzhen

    2017-06-01

    Research of the resistance characteristics of YBCO tape under short-time DC large current impact is the foundation of the developing DC superconducting fault current limiter (SFCL) for voltage source converter-based high voltage direct current system (VSC-HVDC), which is one of the valid approaches to solve the problems of renewable energy integration. SFCL can limit DC short-circuit and enhance the interrupting capabilities of DC circuit breakers. In this paper, under short-time DC large current impacts, the resistance features of naked tape of YBCO tape are studied to find the resistance - temperature change rule and the maximum impact current. The influence of insulation for the resistance - temperature characteristics of YBCO tape is studied by comparison tests with naked tape and insulating tape in 77 K. The influence of operating temperature on the tape is also studied under subcooled liquid nitrogen condition. For the current impact security of YBCO tape, the critical current degradation and top temperature are analyzed and worked as judgment standards. The testing results is helpful for in developing SFCL in VSC-HVDC.

  17. Equivalence between short-time biphasic and incompressible elastic material responses.

    Science.gov (United States)

    Ateshian, Gerard A; Ellis, Benjamin J; Weiss, Jeffrey A

    2007-06-01

    Porous-permeable tissues have often been modeled using porous media theories such as the biphasic theory. This study examines the equivalence of the short-time biphasic and incompressible elastic responses for arbitrary deformations and constitutive relations from first principles. This equivalence is illustrated in problems of unconfined compression of a disk, and of articular contact under finite deformation, using two different constitutive relations for the solid matrix of cartilage, one of which accounts for the large disparity observed between the tensile and compressive moduli in this tissue. Demonstrating this equivalence under general conditions provides a rationale for using available finite element codes for incompressible elastic materials as a practical substitute for biphasic analyses, so long as only the short-time biphasic response is sought. In practice, an incompressible elastic analysis is representative of a biphasic analysis over the short-term response deltatelasticity tensor, and K is the hydraulic permeability tensor of the solid matrix. Certain notes of caution are provided with regard to implementation issues, particularly when finite element formulations of incompressible elasticity employ an uncoupled strain energy function consisting of additive deviatoric and volumetric components.

  18. Evaluation of skeletal muscle during exercise on short repetition time MR imaging

    International Nuclear Information System (INIS)

    Yoshioka, Hiroshi; Niitsu, Mamoru; Anno, Izumi; Takahashi, Hideyuki; Kuno, Shinya; Matsumoto, Kunihiko; Itai, Yuji

    1992-01-01

    There have been many reports on the effects of exercise on skeletal muscle signal intensities based on magnetic resonance (MR) imaging. These images were obtained using T 2 -weighted MR images. The purpose of this study was to observe muscles during exercise while shortening the repetition time (TR) on spin echo images. In addition, inactive and active muscles were differentiated in the same manner. T 2 values of the tibialis anterior m. were calculated from TR=400 ms to TR=3000 ms. These values were mostly constant and didn't depend upon TR. Increases in signal intensities of the exercise muscles could be observed on the short TR (600 ms) MR images since the changes of the signal intensities mainly depend upon T 2 values. Thus, the T 2 value is useful as a quantitative index to assess the exercise muscle even on the short TR MR images. (author)

  19. Nonlinear response of vessel walls due to short-time thermomechanical loading

    International Nuclear Information System (INIS)

    Pfeiffer, P.A.; Kulak, R.F.

    1994-01-01

    Maintaining structural integrity of the reactor pressure vessel (RPV) during a postulated core melt accident is an important safety consideration in the design of the vessel. This study addresses the failure predictions of the vessel due to thermal and pressure loadings fro the molten core debris depositing on the lower head of the vessel. Different loading combinations were considered based on the dead load, yield stress assumptions, material response and internal pressurization. The analyses considered only short term failure (quasi static) modes, long term failure modes were not considered. Short term failure modes include plastic instabilities of the structure and failure due to exceeding the failure strain. Long term failure odes would be caused by creep rupture that leads to plastic instability of the structure. Due to the sort time durations analyzed, creep was not considered in the analyses presented

  20. Short-term memory loss over time without retroactive stimulus interference.

    Science.gov (United States)

    Cowan, Nelson; AuBuchon, Angela M

    2008-02-01

    A key question in cognitive psychology is whether information in short-term memory is lost as a function of time. Lewandowsky, Duncan, and Brown (2004) argued against that memory loss because forgetting in serial recall occurred to the same extent across serial positions regardless of the rate of recall. However, we believe Lewandowsky et al. (2004) only prevented one of two types of rehearsal; they did not prevent nonarticulatory rehearsal via attention. To prevent articulatory and nonarticulatory rehearsal without introducing interference, we presented unevenly timed stimuli for serial recall and, on some trials, required that the timing of stimuli be reproduced in the response. In those trials only, evidence of memory loss over time emerged. Further research is needed to identify whether this memory loss is decay or lost distinctiveness.

  1. Micro-Doppler Ambiguity Resolution Based on Short-Time Compressed Sensing

    Directory of Open Access Journals (Sweden)

    Jing-bo Zhuang

    2015-01-01

    Full Text Available When using a long range radar (LRR to track a target with micromotion, the micro-Doppler embodied in the radar echoes may suffer from ambiguity problem. In this paper, we propose a novel method based on compressed sensing (CS to solve micro-Doppler ambiguity. According to the RIP requirement, a sparse probing pulse train with its transmitting time random is designed. After matched filtering, the slow-time echo signals of the micromotion target can be viewed as randomly sparse sampling of Doppler spectrum. Select several successive pulses to form a short-time window and the CS sensing matrix can be built according to the time stamps of these pulses. Then performing Orthogonal Matching Pursuit (OMP, the unambiguous micro-Doppler spectrum can be obtained. The proposed algorithm is verified using the echo signals generated according to the theoretical model and the signals with micro-Doppler signature produced using the commercial electromagnetic simulation software FEKO.

  2. Analysis of Seasonal Signal in GPS Short-Baseline Time Series

    Science.gov (United States)

    Wang, Kaihua; Jiang, Weiping; Chen, Hua; An, Xiangdong; Zhou, Xiaohui; Yuan, Peng; Chen, Qusen

    2018-04-01

    Proper modeling of seasonal signals and their quantitative analysis are of interest in geoscience applications, which are based on position time series of permanent GPS stations. Seasonal signals in GPS short-baseline (paper, to better understand the seasonal signal in GPS short-baseline time series, we adopted and processed six different short-baselines with data span that varies from 2 to 14 years and baseline length that varies from 6 to 1100 m. To avoid seasonal signals that are overwhelmed by noise, each of the station pairs is chosen with significant differences in their height (> 5 m) or type of the monument. For comparison, we also processed an approximately zero baseline with a distance of pass-filtered (BP) noise is valid for approximately 40% of the baseline components, and another 20% of the components can be best modeled by a combination of the first-order Gauss-Markov (FOGM) process plus white noise (WN). The TEM displacements are then modeled by considering the monument height of the building structure beneath the GPS antenna. The median contributions of TEM to the annual amplitude in the vertical direction are 84% and 46% with and without additional parts of the monument, respectively. Obvious annual signals with amplitude > 0.4 mm in the horizontal direction are observed in five short-baselines, and the amplitudes exceed 1 mm in four of them. These horizontal seasonal signals are likely related to the propagation of daily/sub-daily TEM displacement or other signals related to the site environment. Mismodeling of the tropospheric delay may also introduce spurious seasonal signals with annual amplitudes of 5 and 2 mm, respectively, for two short-baselines with elevation differences greater than 100 m. The results suggest that the monument height of the additional part of a typical GPS station should be considered when estimating the TEM displacement and that the tropospheric delay should be modeled cautiously, especially with station pairs with

  3. Short-term wind power forecasting: probabilistic and space-time aspects

    DEFF Research Database (Denmark)

    Tastu, Julija

    work deals with the proposal and evaluation of new mathematical models and forecasting methods for short-term wind power forecasting, accounting for space-time dynamics based on geographically distributed information. Different forms of power predictions are considered, starting from traditional point...... into the corresponding models are analysed. As a final step, emphasis is placed on generating space-time trajectories: this calls for the prediction of joint multivariate predictive densities describing wind power generation at a number of distributed locations and for a number of successive lead times. In addition......Optimal integration of wind energy into power systems calls for high quality wind power predictions. State-of-the-art forecasting systems typically provide forecasts for every location individually, without taking into account information coming from the neighbouring territories. It is however...

  4. Short-time beta grain growth kinetics for a conventional titanium alloy

    International Nuclear Information System (INIS)

    Semiatin, S.L.; Sukonnik, I.M.

    1996-01-01

    The kinetics of beta grain growth during short-time, supertransus heat treatment of Ti-5Al-4V were determined using a salt-pot technique. The finite-time, subtransus temperature transient during salt-pot heating was quantified through measurements of the heat transfer coefficient characterizing conduction across the salt-titanium interface and a simple heat conduction analysis which incorporated this heat transfer coefficient. Grain size versus time data adjusted to account for the subtransus temperature transient were successfully fit to the parabolic grain growth law d n - d 0 n = kt exp(-Q/RT) using an exponent n equal to 2.0. Comparison of the present results to rapid, continuous heat treatment data in the literature for a similar titanium alloy revealed a number of semi-quantitative similarities

  5. Response probability and response time: a straight line, the Tagging/Retagging interpretation of short term memory, an operational definition of meaningfulness and short term memory time decay and search time.

    Science.gov (United States)

    Tarnow, Eugen

    2008-12-01

    The functional relationship between correct response probability and response time is investigated in data sets from Rubin, Hinton and Wenzel, J Exp Psychol Learn Mem Cogn 25:1161-1176, 1999 and Anderson, J Exp Psychol [Hum Learn] 7:326-343, 1981. The two measures are linearly related through stimulus presentation lags from 0 to 594 s in the former experiment and for repeated learning of words in the latter. The Tagging/Retagging interpretation of short term memory is introduced to explain this linear relationship. At stimulus presentation the words are tagged. This tagging level drops slowly with time. When a probe word is reintroduced the tagging level has to increase for the word to be properly identified leading to a delay in response time. The tagging time is related to the meaningfulness of the words used-the more meaningful the word the longer the tagging time. After stimulus presentation the tagging level drops in a logarithmic fashion to 50% after 10 s and to 20% after 240 s. The incorrect recall and recognition times saturate in the Rubin et al. data set (they are not linear for large time lags), suggesting a limited time to search the short term memory structure: the search time for recall of unusual words is 1.7 s. For recognition of nonsense words the corresponding time is about 0.4 s, similar to the 0.243 s found in Cavanagh (1972).

  6. Short- and long-run time-of-use price elasticities in Swiss residential electricity demand

    International Nuclear Information System (INIS)

    Filippini, Massimo

    2011-01-01

    This paper presents an empirical analysis on the residential demand for electricity by time-of-day. This analysis has been performed using aggregate data at the city level for 22 Swiss cities for the period 2000-2006. For this purpose, we estimated two log-log demand equations for peak and off-peak electricity consumption using static and dynamic partial adjustment approaches. These demand functions were estimated using several econometric approaches for panel data, for example LSDV and RE for static models, and LSDV and corrected LSDV estimators for dynamic models. The attempt of this empirical analysis has been to highlight some of the characteristics of the Swiss residential electricity demand. The estimated short-run own price elasticities are lower than 1, whereas in the long-run these values are higher than 1. The estimated short-run and long-run cross-price elasticities are positive. This result shows that peak and off-peak electricity are substitutes. In this context, time differentiated prices should provide an economic incentive to customers so that they can modify consumption patterns by reducing peak demand and shifting electricity consumption from peak to off-peak periods. - Highlights: → Empirical analysis on the residential demand for electricity by time-of-day. → Estimators for dynamic panel data. → Peak and off-peak residential electricity are substitutes.

  7. Study of surfaces and surface layers on high temperature materials after short-time thermal loads

    International Nuclear Information System (INIS)

    Bolt, H.; Hoven, H.; Koizlik, K.; Linke, J.; Nickel, H.; Wallura, E.

    1985-11-01

    Being part of the plasma-wall interaction during TOKAMAK operation, erosion- and redeposition processes of First Wall materials substantially influence plasma parameters as well as the properties of the First Wall. An important redeposition process of eroded material is the formation of thin films by atomic condensation. Examinations of First Wall components after TOKAMAK operation lead to the assumption that these thin metallic films tend to agglomerate to small particles under subsequent heat load. In laboratory experiments it is shown that thin metallic films on various substrates can agglomerate under short time high heat fluxes and also under longer lasting lower thermal loads, thus verifying the ''agglomeration hypothesis''. (orig.) [de

  8. A Statistical and Spectral Model for Representing Noisy Sounds with Short-Time Sinusoids

    Directory of Open Access Journals (Sweden)

    Myriam Desainte-Catherine

    2005-07-01

    Full Text Available We propose an original model for noise analysis, transformation, and synthesis: the CNSS model. Noisy sounds are represented with short-time sinusoids whose frequencies and phases are random variables. This spectral and statistical model represents information about the spectral density of frequencies. This perceptually relevant property is modeled by three mathematical parameters that define the distribution of the frequencies. This model also represents the spectral envelope. The mathematical parameters are defined and the analysis algorithms to extract these parameters from sounds are introduced. Then algorithms for generating sounds from the parameters of the model are presented. Applications of this model include tools for composers, psychoacoustic experiments, and pedagogy.

  9. Quantum Dynamics with Short-Time Trajectories and Minimal Adaptive Basis Sets.

    Science.gov (United States)

    Saller, Maximilian A C; Habershon, Scott

    2017-07-11

    Methods for solving the time-dependent Schrödinger equation via basis set expansion of the wave function can generally be categorized as having either static (time-independent) or dynamic (time-dependent) basis functions. We have recently introduced an alternative simulation approach which represents a middle road between these two extremes, employing dynamic (classical-like) trajectories to create a static basis set of Gaussian wavepackets in regions of phase-space relevant to future propagation of the wave function [J. Chem. Theory Comput., 11, 8 (2015)]. Here, we propose and test a modification of our methodology which aims to reduce the size of basis sets generated in our original scheme. In particular, we employ short-time classical trajectories to continuously generate new basis functions for short-time quantum propagation of the wave function; to avoid the continued growth of the basis set describing the time-dependent wave function, we employ Matching Pursuit to periodically minimize the number of basis functions required to accurately describe the wave function. Overall, this approach generates a basis set which is adapted to evolution of the wave function while also being as small as possible. In applications to challenging benchmark problems, namely a 4-dimensional model of photoexcited pyrazine and three different double-well tunnelling problems, we find that our new scheme enables accurate wave function propagation with basis sets which are around an order-of-magnitude smaller than our original trajectory-guided basis set methodology, highlighting the benefits of adaptive strategies for wave function propagation.

  10. Road Short-Term Travel Time Prediction Method Based on Flow Spatial Distribution and the Relations

    Directory of Open Access Journals (Sweden)

    Mingjun Deng

    2016-01-01

    Full Text Available There are many short-term road travel time forecasting studies based on time series, but indeed, road travel time not only relies on the historical travel time series, but also depends on the road and its adjacent sections history flow. However, few studies have considered that. This paper is based on the correlation of flow spatial distribution and the road travel time series, applying nearest neighbor and nonparametric regression method to build a forecasting model. In aspect of spatial nearest neighbor search, three different space distances are defined. In addition, two forecasting functions are introduced: one combines the forecasting value by mean weight and the other uses the reciprocal of nearest neighbors distance as combined weight. Three different distances are applied in nearest neighbor search, which apply to the two forecasting functions. For travel time series, the nearest neighbor and nonparametric regression are applied too. Then minimizing forecast error variance is utilized as an objective to establish the combination model. The empirical results show that the combination model can improve the forecast performance obviously. Besides, the experimental results of the evaluation for the computational complexity show that the proposed method can satisfy the real-time requirement.

  11. Mining biological information from 3D short time-series gene expression data: the OPTricluster algorithm.

    Science.gov (United States)

    Tchagang, Alain B; Phan, Sieu; Famili, Fazel; Shearer, Heather; Fobert, Pierre; Huang, Yi; Zou, Jitao; Huang, Daiqing; Cutler, Adrian; Liu, Ziying; Pan, Youlian

    2012-04-04

    Nowadays, it is possible to collect expression levels of a set of genes from a set of biological samples during a series of time points. Such data have three dimensions: gene-sample-time (GST). Thus they are called 3D microarray gene expression data. To take advantage of the 3D data collected, and to fully understand the biological knowledge hidden in the GST data, novel subspace clustering algorithms have to be developed to effectively address the biological problem in the corresponding space. We developed a subspace clustering algorithm called Order Preserving Triclustering (OPTricluster), for 3D short time-series data mining. OPTricluster is able to identify 3D clusters with coherent evolution from a given 3D dataset using a combinatorial approach on the sample dimension, and the order preserving (OP) concept on the time dimension. The fusion of the two methodologies allows one to study similarities and differences between samples in terms of their temporal expression profile. OPTricluster has been successfully applied to four case studies: immune response in mice infected by malaria (Plasmodium chabaudi), systemic acquired resistance in Arabidopsis thaliana, similarities and differences between inner and outer cotyledon in Brassica napus during seed development, and to Brassica napus whole seed development. These studies showed that OPTricluster is robust to noise and is able to detect the similarities and differences between biological samples. Our analysis showed that OPTricluster generally outperforms other well known clustering algorithms such as the TRICLUSTER, gTRICLUSTER and K-means; it is robust to noise and can effectively mine the biological knowledge hidden in the 3D short time-series gene expression data.

  12. Measurement of radon-222 concentration in environment sampled within short time using charcoal detector

    International Nuclear Information System (INIS)

    Yamasaki, Tadashi; Sekiyama, Shigenobu; Tokin, Mina; Nakayasu, Yumiko; Watanabe, Tamaki.

    1994-01-01

    The concentration of 222 Rn in air sampled within a very short period of time was measured using activated charcoal as the adsorber. The detector is the plastic canister containing mixture of the activated charcoal and the silica gel. The radon gas was adsorbed in the charcoal in the radon chamber at the temperature of 25degC. A little amount of liquid scintillation cocktail was added into the vial of liquid scintillation counter with the canister. The radon in the charcoal was extracted in the liquid scintillation cocktail. Alpha particles emitted from radon and its daughter nuclei in the cocktail were detected using the liquid scintillation counter. Present method has advantages of not only short sampling time of air but also adsorption of radon in charcoal under a constant temperature. The concentration of radon in air down to 2 Bq/m 3 could be detected. A kinetic model for adsorption of radon in the charcoal is also presented. The ratio of radon concentration in the charcoal to that in air under the equilibrium state of adsorption was estimated to be from 6.1 to 6.8 m 3 /kg at the temperature of 25degC. (author)

  13. Effective description of the short-time dynamics in open quantum systems

    Science.gov (United States)

    Rossi, Matteo A. C.; Foti, Caterina; Cuccoli, Alessandro; Trapani, Jacopo; Verrucchi, Paola; Paris, Matteo G. A.

    2017-09-01

    We address the dynamics of a bosonic system coupled to either a bosonic or a magnetic environment and derive a set of sufficient conditions that allow one to describe the dynamics in terms of the effective interaction with a classical fluctuating field. We find that for short interaction times the dynamics of the open system is described by a Gaussian noise map for several different interaction models and independently on the temperature of the environment. In order to go beyond a qualitative understanding of the origin and physical meaning of the above short-time constraint, we take a general viewpoint and, based on an algebraic approach, suggest that any quantum environment can be described by classical fields whenever global symmetries lead to the definition of environmental operators that remain well defined when increasing the size, i.e., the number of dynamical variables, of the environment. In the case of the bosonic environment this statement is exactly demonstrated via a constructive procedure that explicitly shows why a large number of environmental dynamical variables and, necessarily, global symmetries, entail the set of conditions derived in the first part of the work.

  14. FREQUENCY COMPONENT EXTRACTION OF HEARTBEAT CUES WITH SHORT TIME FOURIER TRANSFORM (STFT

    Directory of Open Access Journals (Sweden)

    Sumarna Sumarna

    2017-01-01

      Electro-acoustic human heartbeat detector have been made with the main parts : (a stetoscope (piece chest, (b mic condenser, (c transistor amplifier, and (d cues analysis program with MATLAB. The frequency components that contained in heartbeat. cues have also been extracted with Short Time Fourier Transform (STFT from 9 volunteers. The results of the analysis showed that heart rate appeared in every cue frequency spectrum with their harmony. The steps of the research were including detector instrument design, test and instrument repair, cues heartbeat recording with Sound Forge 10 program and stored in wav file ; cues breaking at the start and the end, and extraction/cues analysis using MATLAB. The MATLAB program included filter (bandpass filter with bandwidth between 0.01 – 110 Hz, cues breaking with hamming window and every part was calculated using Fourier Transform (STFT mechanism and the result were shown in frequency spectrum graph.   Keywords: frequency components extraction, heartbeat cues, Short Time Fourier Transform

  15. Usage of OpenStack Virtual Machine and MATLAB HPC Add-on leads to faster turnaround

    KAUST Repository

    Van Waveren, Matthijs

    2017-03-16

    We need to run hundreds of MATLAB® simulations while changing the parameters between each simulation. These simulations need to be run sequentially, and the parameters are defined manually from one simulation to the next. This makes this type of workload unsuitable for a shared cluster. For this reason we are using a cluster running in an OpenStack® Virtual Machine and are using the MATLAB HPC Add-on for submitting jobs to the cluster. As a result we are now able to have a turnaround time for the simulations of the order of a few hours, instead of the 24 hours needed on a local workstation.

  16. New solutions for the short-time analysis of geothermal vertical boreholes

    Energy Technology Data Exchange (ETDEWEB)

    Lamarche, Louis; Beauchamp, Benoit [Ecole de Technologie Supereure, 1100 Notre-Dame Ouest, Montreal (Canada)

    2007-04-15

    Many models, either numerical or analytical, have been proposed to analyse the thermal response of vertical heat exchangers that are used in ground coupled heat pump systems (GCHP). In both approaches, most of the models are valid after few hours of operation since they neglect the heat capacity of the borehole. This is valid for design purposes, where the time of interest is in the order of months and years. Recently, the short time response of vertical boreholes became a subject of interest. In this paper, we present a new analytical approach to treat this problem. It solves the exact solution for concentric cylinders and is a good approximation for the familiar U-tube configuration. (author)

  17. Spatial filtering velocimetry revisited: exact short-time detecting schemes from arbitrarily small-size reticles

    International Nuclear Information System (INIS)

    Ando, S; Nara, T; Kurihara, T

    2014-01-01

    Spatial filtering velocimetry was proposed in 1963 by Ator as a velocity-sensing technique for aerial camera-control systems. The total intensity of a moving surface is observed through a set of parallel-slit reticles, resulting in a narrow-band temporal signal whose frequency is directly proportional to the image velocity. However, even despite its historical importance and inherent technical advantages, the mathematical formulation of this technique is only valid when infinite-length observation in both space and time is possible, which causes significant errors in most applications where a small receptive window and high resolution in both axes are desired. In this study, we apply a novel mathematical technique, the weighted integral method, to solve this problem, and obtain exact sensing schemes and algorithms for finite (arbitrarily small but non-zero) size reticles and short-time estimation. Practical considerations for utilizing these schemes are also explored both theoretically and experimentally. (paper)

  18. Verification of short lead time forecast models: applied to Kp and Dst forecasting

    Science.gov (United States)

    Wintoft, Peter; Wik, Magnus

    2016-04-01

    In the ongoing EU/H2020 project PROGRESS models that predicts Kp, Dst, and AE from L1 solar wind data will be used as inputs to radiation belt models. The possible lead times from L1 measurements are shorter (10s of minutes to hours) than the typical duration of the physical phenomena that should be forecast. Under these circumstances several metrics fail to single out trivial cases, such as persistence. In this work we explore metrics and approaches for short lead time forecasts. We apply these to current Kp and Dst forecast models. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 637302.

  19. Critical dynamics of the Potts model: short-time Monte Carlo simulations

    International Nuclear Information System (INIS)

    Silva, Roberto da; Drugowich de Felicio, J.R.

    2004-01-01

    We calculate the new dynamic exponent θ of the 4-state Potts model, using short-time simulations. Our estimates θ1=-0.0471(33) and θ2=-0.0429(11) obtained by following the behavior of the magnetization or measuring the evolution of the time correlation function of the magnetization corroborate the conjecture by Okano et al. [Nucl. Phys. B 485 (1997) 727]. In addition, these values agree with previous estimate of the same dynamic exponent for the two-dimensional Ising model with three-spin interactions in one direction, that is known to belong to the same universality class as the 4-state Potts model. The anomalous dimension of initial magnetization x0=zθ+β/ν is calculated by an alternative way that mixes two different initial conditions. We have also estimated the values of the static exponents β and ν. They are in complete agreement with the pertinent results of the literature

  20. Burn-up measurements of LEU fuel for short cooling times

    International Nuclear Information System (INIS)

    Pereda B, C.; Henriquez A, C.; Klein D, J.; Medel R, J.

    2005-01-01

    The measurements presented in this work were made essentially at in-pool gamma-spectrometric facility, installed inside of the secondary pool of the RECH-1 research reactor, where the measured fuel elements are under 2 meters of water. The main reason for using the in-pool facility was because of its capability to measure the burning of fuel elements without having to wait so long, that is with only 5 cooling days, which are the usual times between reactor operations. Regarding these short cooling times, this work confirms again the possibility of using the 95 Zr as a promising burnup monitor, in spite of the rough approximations used to do it. These results are statistically reasonable within the range calculated using codes. The work corroborates previous results, presented in Santiago de Chile, and it suggests future improvements in that way. (author)

  1. Optimal filtering of dynamics in short-time features for music organization

    DEFF Research Database (Denmark)

    Arenas-García, Jerónimo; Larsen, Jan; Hansen, Lars Kai

    2006-01-01

    There is an increasing interest in customizable methods for organizing music collections. Relevant music characterization can be obtained from short-time features, but it is not obvious how to combine them to get useful information. In this work, a novel method, denoted as the Positive Constrained...... Orthonormalized Partial Least Squares (POPLS), is proposed. Working on the periodograms of MFCCs time series, this supervised method finds optimal filters which pick up the most discriminative temporal information for any music organization task. Two examples are presented in the paper, the first being a simple...... proof-of-concept, where an altosax with and without vibrato is modelled. A more complex \\$11\\$ music genre classification setup is also investigated to illustrate the robustness and validity of the proposed method on larger datasets. Both experiments showed the good properties of our method, as well...

  2. Measurement and deconvolution of detector response time for short HPM pulses: Part 1, Microwave diodes

    International Nuclear Information System (INIS)

    Bolton, P.R.

    1987-06-01

    A technique is described for measuring and deconvolving response times of microwave diode detection systems in order to generate corrected input signals typical of an infinite detection rate. The method has been applied to cases of 2.86 GHz ultra-short HPM pulse detection where pulse rise time is comparable to that of the detector; whereas, the duration of a few nanoseconds is significantly longer. Results are specified in terms of the enhancement of equivalent deconvolved input voltages for given observed voltages. The convolution integral imposes the constraint of linear detector response to input power levels. This is physically equivalent to the conservation of integrated pulse energy in the deconvolution process. The applicable dynamic range of a microwave diode is therefore limited to a smaller signal region as determined by its calibration

  3. Short version of the Zimbardo Time Perspective Inventory (ZTPI-short) with and without the Future-Negative scale, verified on nationally representative samples

    Czech Academy of Sciences Publication Activity Database

    Košťál, Jaroslav; Klicperová-Baker, Martina; Lukavská, K.; Lukavský, Jiří

    2016-01-01

    Roč. 25, č. 2 (2016), s. 169-192 ISSN 0961-463X Institutional support: RVO:68081740 Keywords : ZTPI * ZTPI-short * time perspective * temporal orientation * representative sample Subject RIV: AN - Psychology Impact factor: 1.206, year: 2016

  4. EXPLORING THE POTENTIAL OF SHORT-TIME FOURIER TRANSFORMS FOR ANALYZING SKIN CONDUCTANCE AND PUPILLOMETRY IN REAL-TIME APPLICATIONS

    International Nuclear Information System (INIS)

    Roger Lew; Brian P. Dyre; Steffen Werner; Jeffrey C. Joe; Brian Wotring; Tuan Tran

    2008-01-01

    The development of real-time predictors of mental workload is critical for the practical application of augmented cognition to human-machine systems. This paper explores a novel method based on a short-time Fourier transform (STFT) for analyzing galvanic skin conductance (SC) and pupillometry time-series data to extract estimates of mental workload with temporal bandwidth high-enough to be useful for augmented cognition applications. We tested the method in the context of a process control task based on the DURESS simulation developed by Vincente and Pawlak (1994; ported to Java by Cosentino, and Ross, 1999). SC, pupil dilation, blink rate, and visual scanning patterns were measured for four participants actively engaged in controlling the simulation. Fault events were introduced that required participants to diagnose errors and make control adjustments to keep the simulator operating within a target range. We were interested in whether the STFT of these measures would produce visible effects of the increase in mental workload and stress associated with these events. Graphical exploratory data analysis of the STFT showed visible increases in the power spectrum across a range of frequencies directly following fault events. We believe this approach shows potential as a relatively unobtrusive, low-cost, high bandwidth measure of mental workload that could be particularly useful for the application of augmented cognition to human-machine systems

  5. EXPLORING THE POTENTIAL OF SHORT-TIME FOURIER TRANSFORMS FOR ANALYZING SKIN CONDUCTANCE AND PUPILLOMETRY IN REAL-TIME APPLICATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Roger Lew; Brian P. Dyre; Steffen Werner; Jeffrey C. Joe; Brian Wotring; Tuan Tran

    2008-09-01

    The development of real-time predictors of mental workload is critical for the practical application of augmented cognition to human-machine systems. This paper explores a novel method based on a short-time Fourier transform (STFT) for analyzing galvanic skin conductance (SC) and pupillometry time-series data to extract estimates of mental workload with temporal bandwidth high-enough to be useful for augmented cognition applications. We tested the method in the context of a process control task based on the DURESS simulation developed by Vincente and Pawlak (1994; ported to Java by Cosentino,& Ross, 1999). SC, pupil dilation, blink rate, and visual scanning patterns were measured for four participants actively engaged in controlling the simulation. Fault events were introduced that required participants to diagnose errors and make control adjustments to keep the simulator operating within a target range. We were interested in whether the STFT of these measures would produce visible effects of the increase in mental workload and stress associated with these events. Graphical exploratory data analysis of the STFT showed visible increases in the power spectrum across a range of frequencies directly following fault events. We believe this approach shows potential as a relatively unobtrusive, low-cost, high bandwidth measure of mental workload that could be particularly useful for the application of augmented cognition to human-machine systems.

  6. Is "Turnaround" a useful model for low-performing schools?

    Directory of Open Access Journals (Sweden)

    Sandra Stotsky

    2015-04-01

    Full Text Available Since passage of the No Child Left Behind act in 2001, all states have been under federal pressure to identify “failing schools.” The US Department of Education has strongly encouraged “turnaround” as an option for schools to use in order to improve student achievement. The study reported here reviewed the research literature on school “turnaround,” with a particular focus on the results in Arkansas of the use of the same “turnaround” partner (America’s Choice for over five years for many of the state’s “failing” elementary, middle, and high schools. There was little evidence to support either this partner or this policy option. The lack of evidence raises a basic question about the usefulness and cost of the federal government’s intervention in local education policy. Nor is it clear how a new program titled Excellence for All now offered by the developers of America’s Choice will differ. It is described as follows: “Excellence for All provides a clear, practical strategy for every student to graduate from high school prepared to succeed in college or in a program of career and technical education that will lead to a successful career.” We are also told: “Excellence for All is aligned with the Common Core State Standards, enabling participating high schools to not just lay the foundation for the Common Core but to get a head start on implementation.” According to a draft of a yet-to-be-voted-on re-authorization of the Elementary and Secondary Education Act (ESEA/NCLB, state departments of education are to submit “college-ready” standards for approval by the USDE if they want Title I funds. However, state legislators, local school board members, parents, and a state’s own higher education academic experts are excluded from approving the standards their state department of education submits, perhaps to ensure that only the “right” standards are submitted. If the language in the current re

  7. End of the nuclear energy era? From Fukushima to the energy policy turnaround; Ende des Atomzeitalters? Von Fukushima in die Energiewende

    Energy Technology Data Exchange (ETDEWEB)

    Piepenbrink, Johannes (comp.)

    2012-07-01

    Due to a violent earthquake and the resulting tsunami, a core melt down resulted at the nuclear power plant Fukushima Daiichi in Japan. Thus, at 30th June, 2011, the Federal Government decided to complete the utilization of the nuclear power in Germany. Is this the end of the atomic age? Under this aspect, the booklet under consideration consists of the following nine contributions: (1) Why is the ''energy policy turnaround'' a social question? (Harald Welzer); (2) Tsunami in the living room: Catastrophes facilitated by the media (Joerg R. Bergmann); (3) Learning from the catastrophe (Manfred Buerger); (4) Perspectives of the nuclear power in Europe and globally (Lutz Mez); (5) Outsider or leader? The 'model Germany' and the European energy policy (Severin Fischer); (6) 'Energy policy turnaround': Quo vadis? (Hardo Bruhns); (7) Energy policy turnarounds in Germany: Motifs and impacts for the European electricity market (Hans-Jochen Luhmann); (8) A short story of the German anti-nuclear movement (Joachim Radkau); (9) Popularity of the apocalypse: Reflections on the cultural history of the fear against nuclear accidents since 1945 (Philipp Gassert).

  8. Airport Gate Activity Monitoring Tool Suite for Improved Turnaround Prediction, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of this research is to create a suite of tools for monitoring airport gate activities with the objective of improving aircraft turnaround. Airport ramp...

  9. Photoluminescence decay dynamics in γ-Ga2O3 nanocrystals: The role of exclusion distance at short time scales

    Science.gov (United States)

    Fernandes, Brian; Hegde, Manu; Stanish, Paul C.; Mišković, Zoran L.; Radovanovic, Pavle V.

    2017-09-01

    We developed a comprehensive theoretical model describing the photoluminescence decay dynamics at short and long time scales based on the donor-acceptor defect interactions in γ-Ga2O3 nanocrystals, and quantitatively determined the importance of exclusion distance and spatial distribution of defects. We allowed for donors and acceptors to be adjacent to each other or separated by different exclusion distances. The optimal exclusion distance was found to be comparable to the donor Bohr radius and have a strong effect on the photoluminescence decay curve at short times. The importance of the exclusion distance at short time scales was confirmed by Monte Carlo simulations.

  10. Investigation of the motion of diesel injection jets using high-speed cinematography and short time holography

    International Nuclear Information System (INIS)

    Eisfeld, F.

    1987-01-01

    The knowledge about the penetration of diesel injection jets, particularly about the flow within the short behind the nozzle, and the arising of droplets from an injection jet is very limited. Experimental investigations are required to describe the process of penetration and spreading of the jet. The research method requires high speed cinematography and short time holography. Problems in the investigation method are described

  11. Chirped or time modulated excitation compared to short pulses for photoacoustic imaging in acoustic attenuating media

    Science.gov (United States)

    Burgholzer, P.; Motz, C.; Lang, O.; Berer, T.; Huemer, M.

    2018-02-01

    In photoacoustic imaging, optically generated acoustic waves transport the information about embedded structures to the sample surface. Usually, short laser pulses are used for the acoustic excitation. Acoustic attenuation increases for higher frequencies, which reduces the bandwidth and limits the spatial resolution. One could think of more efficient waveforms than single short pulses, such as pseudo noise codes, chirped, or harmonic excitation, which could enable a higher information-transfer from the samples interior to its surface by acoustic waves. We used a linear state space model to discretize the wave equation, such as the Stoke's equation, but this method could be used for any other linear wave equation. Linear estimators and a non-linear function inversion were applied to the measured surface data, for onedimensional image reconstruction. The proposed estimation method allows optimizing the temporal modulation of the excitation laser such that the accuracy and spatial resolution of the reconstructed image is maximized. We have restricted ourselves to one-dimensional models, as for higher dimensions the one-dimensional reconstruction, which corresponds to the acoustic wave without attenuation, can be used as input for any ultrasound imaging method, such as back-projection or time-reversal method.

  12. Gene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times

    Directory of Open Access Journals (Sweden)

    Rao Nagesha AS

    2009-09-01

    Full Text Available Abstract Background Gene expression profiling of spontaneous tumors in the dog offers a unique translational opportunity to identify prognostic biomarkers and signaling pathways that are common to both canine and human. Osteosarcoma (OS accounts for approximately 80% of all malignant bone tumors in the dog. Canine OS are highly comparable with their human counterpart with respect to histology, high metastatic rate and poor long-term survival. This study investigates the prognostic gene profile among thirty-two primary canine OS using canine specific cDNA microarrays representing 20,313 genes to identify genes and cellular signaling pathways associated with survival. This, the first report of its kind in dogs with OS, also demonstrates the advantages of cross-species comparison with human OS. Results The 32 tumors were classified into two prognostic groups based on survival time (ST. They were defined as short survivors (dogs with poor prognosis: surviving fewer than 6 months and long survivors (dogs with better prognosis: surviving 6 months or longer. Fifty-one transcripts were found to be differentially expressed, with common upregulation of these genes in the short survivors. The overexpressed genes in short survivors are associated with possible roles in proliferation, drug resistance or metastasis. Several deregulated pathways identified in the present study, including Wnt signaling, Integrin signaling and Chemokine/cytokine signaling are comparable to the pathway analysis conducted on human OS gene profiles, emphasizing the value of the dog as an excellent model for humans. Conclusion A molecular-based method for discrimination of outcome for short and long survivors is useful for future prognostic stratification at initial diagnosis, where genes and pathways associated with cell cycle/proliferation, drug resistance and metastasis could be potential targets for diagnosis and therapy. The similarities between human and canine OS makes the

  13. Teacher Pay-for-Performance in School Turnaround: How Bonuses and Differentiated Pay Scales Can Help Support School Turnaround. Meeting the Turnaround Challenge: Strategies, Resources & Tools to Transform a Framework into Practice

    Science.gov (United States)

    Mass Insight Education (NJ1), 2009

    2009-01-01

    Given the importance of good teaching and leadership for school success, turnaround schools should think carefully about how to structure professional environments that reward and motivate excellence. A system of "Pay-for-Contribution" that includes tools such as hard-to-staff and skill shortage pay, performance pay, and/or retention…

  14. Robust and Adaptive Online Time Series Prediction with Long Short-Term Memory

    Directory of Open Access Journals (Sweden)

    Haimin Yang

    2017-01-01

    Full Text Available Online time series prediction is the mainstream method in a wide range of fields, ranging from speech analysis and noise cancelation to stock market analysis. However, the data often contains many outliers with the increasing length of time series in real world. These outliers can mislead the learned model if treated as normal points in the process of prediction. To address this issue, in this paper, we propose a robust and adaptive online gradient learning method, RoAdam (Robust Adam, for long short-term memory (LSTM to predict time series with outliers. This method tunes the learning rate of the stochastic gradient algorithm adaptively in the process of prediction, which reduces the adverse effect of outliers. It tracks the relative prediction error of the loss function with a weighted average through modifying Adam, a popular stochastic gradient method algorithm for training deep neural networks. In our algorithm, the large value of the relative prediction error corresponds to a small learning rate, and vice versa. The experiments on both synthetic data and real time series show that our method achieves better performance compared to the existing methods based on LSTM.

  15. Robust and Adaptive Online Time Series Prediction with Long Short-Term Memory.

    Science.gov (United States)

    Yang, Haimin; Pan, Zhisong; Tao, Qing

    2017-01-01

    Online time series prediction is the mainstream method in a wide range of fields, ranging from speech analysis and noise cancelation to stock market analysis. However, the data often contains many outliers with the increasing length of time series in real world. These outliers can mislead the learned model if treated as normal points in the process of prediction. To address this issue, in this paper, we propose a robust and adaptive online gradient learning method, RoAdam (Robust Adam), for long short-term memory (LSTM) to predict time series with outliers. This method tunes the learning rate of the stochastic gradient algorithm adaptively in the process of prediction, which reduces the adverse effect of outliers. It tracks the relative prediction error of the loss function with a weighted average through modifying Adam, a popular stochastic gradient method algorithm for training deep neural networks. In our algorithm, the large value of the relative prediction error corresponds to a small learning rate, and vice versa. The experiments on both synthetic data and real time series show that our method achieves better performance compared to the existing methods based on LSTM.

  16. Decentralized energy policy turnaround. Opportunities and challenges; Dezentrale Energiewende. Chancen und Herausforderungen

    Energy Technology Data Exchange (ETDEWEB)

    Eiselt, Juergen

    2012-07-01

    This book supplies a comprehensive inventory of an already beginning decentralized energy policy turnaround. The potentials of an effective energy policy turnaround are described by means of present structures, technologies and scientifically proven results. The book presents new technologies and effective concepts in order to replace the centralised energy supply by decentralized structures. The reduction of expenses and energy-autonomous systems up to the zero-tariff heating are the main impulses for the utilization of decentralized forms of energy.

  17. A combination of HARMONIE short time direct normal irradiance forecasts and machine learning: The #hashtdim procedure

    Science.gov (United States)

    Gastón, Martín; Fernández-Peruchena, Carlos; Körnich, Heiner; Landelius, Tomas

    2017-06-01

    The present work describes the first approach of a new procedure to forecast Direct Normal Irradiance (DNI): the #hashtdim that treats to combine ground information and Numerical Weather Predictions. The system is centered in generate predictions for the very short time. It combines the outputs from the Numerical Weather Prediction Model HARMONIE with an adaptive methodology based on Machine Learning. The DNI predictions are generated with 15-minute and hourly temporal resolutions and presents 3-hourly updates. Each update offers forecasts to the next 12 hours, the first nine hours are generated with 15-minute temporal resolution meanwhile the last three hours present hourly temporal resolution. The system is proved over a Spanish emplacement with BSRN operative station in south of Spain (PSA station). The #hashtdim has been implemented in the framework of the Direct Normal Irradiance Nowcasting methods for optimized operation of concentrating solar technologies (DNICast) project, under the European Union's Seventh Programme for research, technological development and demonstration framework.

  18. Short-range correlations in an extended time-dependent mean-field theory

    International Nuclear Information System (INIS)

    Madler, P.

    1982-01-01

    A generalization is performed of the time-dependent mean-field theory by an explicit inclusion of strong short-range correlations on a level of microscopic reversibility relating them to realistic nucleon-nucleon forces. Invoking a least action principle for correlated trial wave functions, equations of motion for the correlation functions and the single-particle model wave function are derived in lowest order of the FAHT cluster expansion. Higher order effects as well as long-range correlations are consider only to the extent to which they contribute to the mean field via a readjusted phenomenological effective two-body interaction. The corresponding correlated stationary problem is investigated and appropriate initial conditions to describe a heavy ion reaction are proposed. The singleparticle density matrix is evaluated

  19. The use of Matlab for colour fuzzy representation of multichannel EEG short time spectra.

    Science.gov (United States)

    Bigan, C; Strungaru, R

    1998-01-01

    During the last years, a lot of EEG research efforts was directed to intelligent methods for automatic analysis of data from multichannel EEG recordings. However, all the applications reported were focused on specific single tasks like detection of one specific "event" in the EEG signal: spikes, sleep spindles, epileptic seizures, K complexes, alpha or other rhythms or even artefacts. The aim of this paper is to present a complex system being able to perform a representation of the dynamic changes in frequency components of each EEG channel. This representation uses colours as a powerful means to show the only one frequency range chosen from the shortest epoch of signal able to be processed with the conventional "Short Time Fast Fourier Transform" (S.T.F.F.T.) method.

  20. Generic short-time propagation of sharp-boundaries wave packets

    Science.gov (United States)

    Granot, E.; Marchewka, A.

    2005-11-01

    A general solution to the "shutter" problem is presented. The propagation of an arbitrary initially bounded wave function is investigated, and the general solution for any such function is formulated. It is shown that the exact solution can be written as an expression that depends only on the values of the function (and its derivatives) at the boundaries. In particular, it is shown that at short times (t << 2mx2/hbar, where x is the distance to the boundaries) the wave function propagation depends only on the wave function's values (or its derivatives) at the boundaries of the region. Finally, we generalize these findings to a non-singular wave function (i.e., for wave packets with finite-width boundaries) and suggest an experimental verification.

  1. The Short-Time Behaviour of VIX Implied Volatilities in a Multifactor Stochastic Volatility Framework

    DEFF Research Database (Denmark)

    Barletta, Andrea; Nicolato, Elisa; Pagliarani, Stefano

    error bounds for VIX futures, options and implied volatilities. In particular, we derive exact asymptotic results for VIX implied volatilities, and their sensitivities, in the joint limit of short time-to-maturity and small log-moneyness. The obtained expansions are explicit, based on elementary...... approximations of equity (SPX) options. However, the generalizations needed to cover the case of VIX options are by no means straightforward as the dynamics of the underlying VIX futures are not explicitly known. To illustrate the accuracy of our technique, we provide numerical implementations for a selection...... functions and they neatly uncover how the VIX skew depends on the specific choice of the volatility and the vol-of-vol processes. Our results are based on perturbation techniques applied to the infinitesimal generator of the underlying process. This methodology has been previously adopted to derive...

  2. Germany's energy turnaround. A joint venture for the future

    International Nuclear Information System (INIS)

    2011-01-01

    The Ethics Committee is sure that nuclear phaseout will be possible within a decade with the energy turnaround measures presented here. Nuclear phaseout is considered necessary and is recommended with the intention to prevent the risk of nuclear power in Germany and to use less risky technologies. The competitive standing of the German industry should not be affected. Science and research, new technologies and the readiness of German industrial organizations to develop new business models for a sustainable economy provides Germany with alternatives, i.e. wind power, solar, hydroelectric, geothermal, biomass, efficient energy use and higher energy efficiency, as well as fossil fuels used with low emissions of climate-relevant gases. Further, a changed human lifestyle with more respect of nature will help to save energy. In the first stage of nuclear phaseout, nuclear power plants will be shut down and decommissioned. Of course, the Ethics Committee is aware that after this stage, there will be long years of intensive work of shielding, saveguarding and finally dismantling.

  3. German energy turnaround and Poland's start in nuclear power? A survey

    International Nuclear Information System (INIS)

    Knopp, Lothar; Gorski, Marek

    2015-01-01

    The book includes contributions from two meetings: 1. Meeting in Berlin, October 8,2014: Energy transition in Poland - historical background, development and actual situation; legal boundary conditions of the entry into nuclear power in Poland; ecologic and economic causes motivation for the atomic energy entry in Poland; promotion systems for renewable energy in Poland, current status and political background; construction of a nuclear power plant in Northern Poland site specific impacts and social assessment. Meeting in Stettin on November 5, 2014: Energy turnaround in Germany -German nuclear phaseout under consideration of EU legislation; ecologic and economic motivation for the energy turnaround in Germany; energy turnaround in Germany - new legal boundary conditions, especially the amendment to tue renewable energy law; contribution of the industry to the energy turnaround - taking the example waste management and waste incineration plants; fracking as a factor of the energy turnaround? - legal boundary conditions and ecologic risks; ecological, ethical and sociopolitical aspects of the energy turnaround in Germany and Poland.

  4. Short time administration of antirheumatic drugs - Methotrexate as a strong inhibitor of osteoblast's proliferation in vitro

    Directory of Open Access Journals (Sweden)

    Annussek Tobias

    2012-09-01

    Full Text Available Abstract Introduction Due to increasing use of disease modifying antirheumatic drugs (DMARDs as first line therapy in rheumatic diseases, dental and maxillofacial practitioner should be aware of drug related adverse events. Especially effects on bone-metabolism and its cells are discussed controversially. Therefore we investigate the in vitro effect of short time administration of low dose methotrexate (MTX on osteoblasts as essential part of bone remodelling cells. Methods Primary bovine osteoblasts (OBs were incubated with various concentrations of MTX, related to tissue concentrations, over a period of fourteen days by using a previously established standard protocol. The effect on cell proliferation as well as mitochondrial activity was assessed by using 3-(4, 5-dimethylthiazol-2-yl 2, 5-diphenyltetrazolium bromide (MTT assay, imaging and counting of living cells. Additionally, immunostaining of extracellular matrix proteins was used to survey osteogenic differentiation. Results All methods indicate a strong inhibition of osteoblast`s proliferation by short time administration of low dose MTX within therapeutically relevant concentrations of 1 to 1000nM, without affecting cell differentiation of middle-stage differentiated OBs in general. More over a significant decrease of cell numbers and mitochondrial activity was found at these MTX concentrations. The most sensitive method seems to be the MTT-assay. MTX-concentration of 0,01nM and concentrations below had no inhibitory effects anymore. Conclusion Even low dose methotrexate acts as a potent inhibitor of osteoblast’s proliferation and mitochondrial metabolism in vitro, without affecting main differentiation of pre-differentiated osteoblasts. These results suggest possible negative effects of DMARDs concerning bone healing and for example osseointegration of dental implants. Especially the specifics of the jaw bone with its high vascularisation and physiological high tissue metabolism

  5. Retention time generates short-term phytoplankton blooms in a shallow microtidal subtropical estuary

    Science.gov (United States)

    Odebrecht, Clarisse; Abreu, Paulo C.; Carstensen, Jacob

    2015-09-01

    In this study it was hypothesised that increasing water retention time promotes phytoplankton blooms in the shallow microtidal Patos Lagoon estuary (PLE). This hypothesis was tested using salinity variation as a proxy of water retention time and chlorophyll a for phytoplankton biomass. Submersible sensors fixed at 5 m depth near the mouth of PLE continuously measured water temperature, salinity and pigments fluorescence (calibrated to chlorophyll a) between March 2010 and 12th of December 2011, with some gaps. Salinity variations were used to separate alternating patterns of outflow of lagoon water (salinity 24; 35% of the time). The two transition phases represented a rapid change from lagoon water outflow to marine water inflow and a more gradually declining salinity between the dominating inflow and outflow conditions. During the latter of these, a significant chlorophyll a increase relative to that expected from a linear mixing relationship was observed at intermediate salinities (10-20). The increase in chlorophyll a was positively related to the duration of the prior coastal water inflow in the PLE. Moreover, chlorophyll a increase was significantly higher during austral spring-summer than autumn-winter, probably due to higher light and nutrient availability in the former. Moreover, the retention time process operating on time scales of days influences the long-term phytoplankton variability in this ecosystem. Comparing these results with monthly data from a nearby long-term water quality monitoring station (1993-2011) support the hypothesis that chlorophyll a accumulations occur after marine inflow events, whereas phytoplankton does not accumulate during high water outflow, when the water residence time is short. These results suggest that changing hydrological pattern is the most important mechanism underlying phytoplankton blooms in the PLE.

  6. Motor Fault Diagnosis Based on Short-time Fourier Transform and Convolutional Neural Network

    Science.gov (United States)

    Wang, Li-Hua; Zhao, Xiao-Ping; Wu, Jia-Xin; Xie, Yang-Yang; Zhang, Yong-Hong

    2017-11-01

    With the rapid development of mechanical equipment, the mechanical health monitoring field has entered the era of big data. However, the method of manual feature extraction has the disadvantages of low efficiency and poor accuracy, when handling big data. In this study, the research object was the asynchronous motor in the drivetrain diagnostics simulator system. The vibration signals of different fault motors were collected. The raw signal was pretreated using short time Fourier transform (STFT) to obtain the corresponding time-frequency map. Then, the feature of the time-frequency map was adaptively extracted by using a convolutional neural network (CNN). The effects of the pretreatment method, and the hyper parameters of network diagnostic accuracy, were investigated experimentally. The experimental results showed that the influence of the preprocessing method is small, and that the batch-size is the main factor affecting accuracy and training efficiency. By investigating feature visualization, it was shown that, in the case of big data, the extracted CNN features can represent complex mapping relationships between signal and health status, and can also overcome the prior knowledge and engineering experience requirement for feature extraction, which is used by traditional diagnosis methods. This paper proposes a new method, based on STFT and CNN, which can complete motor fault diagnosis tasks more intelligently and accurately.

  7. Multi-time-scale heat transfer modeling of turbid tissues exposed to short-pulsed irradiations.

    Science.gov (United States)

    Kim, Kyunghan; Guo, Zhixiong

    2007-05-01

    A combined hyperbolic radiation and conduction heat transfer model is developed to simulate multi-time-scale heat transfer in turbid tissues exposed to short-pulsed irradiations. An initial temperature response of a tissue to an ultrashort pulse irradiation is analyzed by the volume-average method in combination with the transient discrete ordinates method for modeling the ultrafast radiation heat transfer. This response is found to reach pseudo steady state within 1 ns for the considered tissues. The single pulse result is then utilized to obtain the temperature response to pulse train irradiation at the microsecond/millisecond time scales. After that, the temperature field is predicted by the hyperbolic heat conduction model which is solved by the MacCormack's scheme with error terms correction. Finally, the hyperbolic conduction is compared with the traditional parabolic heat diffusion model. It is found that the maximum local temperatures are larger in the hyperbolic prediction than the parabolic prediction. In the modeled dermis tissue, a 7% non-dimensional temperature increase is found. After about 10 thermal relaxation times, thermal waves fade away and the predictions between the hyperbolic and parabolic models are consistent.

  8. Short locking time and low jitter phase-locked loop based on slope charge pump control

    International Nuclear Information System (INIS)

    Guo Zhongjie; Liu Youbao; Wu Longsheng; Wang Xihu; Tang Wei

    2010-01-01

    A novel structure of a phase-locked loop (PLL) characterized by a short locking time and low jitter is presented, which is realized by generating a linear slope charge pump current dependent on monitoring the output of the phase frequency detector (PFD) to implement adaptive bandwidth control. This improved PLL is created by utilizing a fast start-up circuit and a slope current control on a conventional charge pump PLL. First, the fast start-up circuit is enabled to achieve fast pre-charging to the loop filter. Then, when the output pulse of the PFD is larger than a minimum value, the charge pump current is increased linearly by the slope current control to ensure a shorter locking time and a lower jitter. Additionally, temperature variation is attenuated with the temperature compensation in the charge pump current design. The proposed PLL has been fabricated in a kind of DSP chip based on a 0.35 μm CMOS process. Comparing the characteristics with the classical PLL, the proposed PLL shows that it can reduce the locking time by 60% with a low peak-to-peak jitter of 0.3% at a wide operation temperature range. (semiconductor integrated circuits)

  9. SHORT DISSIPATION TIMES OF PROTO-PLANETARY DISKS: AN ARTIFACT OF SELECTION EFFECTS?

    International Nuclear Information System (INIS)

    Pfalzner, Susanne; Steinhausen, Manuel; Menten, Karl

    2014-01-01

    The frequency of disks around young stars, a key parameter for understanding planet formation, is most readily determined in young stellar clusters where many relatively coeval stars are located in close proximity. Observational studies seem to show that the disk frequency decreases rapidly with cluster age with <10% of cluster stars retaining their disks for longer than 2-6 Myr. Given that at least half of all stars in the field seem to harbor one or more planets, this would imply extremely fast disk dispersal and rapid planet growth. Here we question the validity of this constraint by demonstrating that the short disk dissipation times inferred to date might have been heavily underestimated by selection effects. Critically, for ages >3 Myr only stars that originally populated the densest areas of very populous clusters, which are prone to disk erosion, are actually considered. This tiny sample may not be representative of the majority of stars. In fact, the higher disk fractions in co-moving groups indicate that it is likely that over 30% of all field stars retain their disks well beyond 10 Myr, leaving ample time for planet growth. Equally, our solar system, with a likely formation time >10 Myr, need no longer be an exception but in fact typical of planetary systems

  10. Development of High Temperature Short Time Vertebrate-Blood Pasteurization Equipment for Tsetse Fly Diets

    Energy Technology Data Exchange (ETDEWEB)

    Moravek, I; Lach, J [Department of Manufacturing Systems, Slovak Technical University Namestie Slobody 17 812 31 Bratislava (Slovakia); Takac, P [Institute of Zoology, SAV, Bratislava (Slovakia)

    2012-07-15

    Tsetse flies feed only on vertebrate blood, but the collection and processing of blood is expensive, it must be stored at -20{sup o}C requiring costly storage rooms and reliable electricity, and it must be irradiated to reduce bacterial contamination. This is tolerable for small colonies, but as colony size increases to service large- scale programmes, the supply and processing of blood becomes critical. Blood is normally collected from cattle at slaughter. This process is necessarily not aseptic, and large-scale collection is only possible where the animals are suspended for bleeding. One alternative to blood decontamination is using the High Temperature Short time Pasteurization (HTST) method. The food processing industry uses pasteurization to reduce bacterial load in a wide range of products. Our previous results indicated that for the control of the blood pasteurization process, to reach satisfactory bacteriological purity and at the same time to prevent the blood from coagulating, it is important to study temperature and time and also some other parameters that could predict blood coagulation. Crucial for blood coagulation is to study blood viscosity. Classical heat exchangers are not suitable for blood pasteurization. In such equipment the blood coagulation depends on temperature and time. Besides the relatively low temperatures, blood is coagulating with cumulative time until total shutdown of blood flow. After a series of experiments we found a solution using microwave systems. To verify the microwave heating concept, we built an experimental workstation. First we verified the accuracy of the applicator design from the aspect of output adaptation to the power source. Also we installed measuring equipment. This system complies with the requirements of quick heating with sufficiently high heat accumulation. By utilizing standard components for the base of the microwave generator, it is possible to markedly reduce the final price of the equipment. (author)

  11. Time domain numerical calculations of the short electron bunch wakefields in resistive structures

    Energy Technology Data Exchange (ETDEWEB)

    Tsakanian, Andranik

    2010-10-15

    The acceleration of electron bunches with very small longitudinal and transverse phase space volume is one of the most actual challenges for the future International Linear Collider and high brightness X-Ray Free Electron Lasers. The exact knowledge on the wake fields generated by the ultra-short electron bunches during its interaction with surrounding structures is a very important issue to prevent the beam quality degradation and to optimize the facility performance. The high accuracy time domain numerical calculations play the decisive role in correct evaluation of the wake fields in advanced accelerators. The thesis is devoted to the development of a new longitudinally dispersion-free 3D hybrid numerical scheme in time domain for wake field calculation of ultra short bunches in structures with walls of finite conductivity. The basic approaches used in the thesis to solve the problem are the following. For materials with high but finite conductivity the model of the plane wave reflection from a conducting half-space is used. It is shown that in the conductive half-space the field components perpendicular to the interface can be neglected. The electric tangential component on the surface contributes to the tangential magnetic field in the lossless area just before the boundary layer. For high conducting media, the task is reduced to 1D electromagnetic problem in metal and the so-called 1D conducting line model can be applied instead of a full 3D space description. Further, a TE/TM (''transverse electric - transverse magnetic'') splitting implicit numerical scheme along with 1D conducting line model is applied to develop a new longitudinally dispersion-free hybrid numerical scheme in the time domain. The stability of the new hybrid numerical scheme in vacuum, conductor and bound cell is studied. The convergence of the new scheme is analyzed by comparison with the well-known analytical solutions. The wakefield calculations for a number of

  12. Short time series analysis of Didymosphenia geminata blooming in the Oreti River, New Zealand

    Science.gov (United States)

    Garcia, T.; Kilroy, C.; Larned, S.; Packman, A. I.; Kumar, P.

    2010-12-01

    The mat-forming diatom Didymosphenia geminata was introduced to New Zealand in 2004, and subsequently spread to many rivers on the south island. D geminata mats are exceptionally dense and thick. Extensive blooms of this introduced organism have substantially modified the benthic environment in many New Zealand rivers, but the factors that contribute to D. geminata blooming are not well understood. We synthesized a sequence of observations of D. geminata areal coverage and thickness to examine physical and chemical controls on the growth and persistence of D germinata. We analyzed the best available time series on the distribution of this organism in New Zealand, observations in the Oreti River every 15 days spanning April 2006 to May 2007. During this period, mean D. geminata coverage of the river bed was ~52% and the mean mat thickness was ~6 mm. Relationships between time-series observations of D. geminata and 13 different physical and chemical variables were analyzed using linear and nonlinear methods. Areal cover and thickness of D geminata mats were found to be influenced by both slow and fast dynamic processes. The spread of the organism, in terms of % cover, was highly correlated with conductivity, ammonium, nitrate, dissolved oxygen, and total nitrogen with short time lags (fast dynamics). Moreover, water clarity, cloud cover, and flow were highly correlated with % cover with long time lags, indicating that these conditions exert long-term control on D. geminata growth. Areal coverage and thickness were found to be highly correlated, but the variables associated with slow and fast dynamics of these two measures were not identical. The variables found to be highly correlated with D. germinata thickness and represented fast dynamics were temperature, dissolved oxygen, conductivity, nitrate, and total nitrogen. Additionally, the variables influencing the slow dynamics of D. germinata thickness were flow, water clarity, turbidity and total phosphorous.

  13. Short Term Prediction of PM10 Concentrations Using Seasonal Time Series Analysis

    Directory of Open Access Journals (Sweden)

    Hamid Hazrul Abdul

    2016-01-01

    Full Text Available Air pollution modelling is one of an important tool that usually used to make short term and long term prediction. Since air pollution gives a big impact especially to human health, prediction of air pollutants concentration is needed to help the local authorities to give an early warning to people who are in risk of acute and chronic health effects from air pollution. Finding the best time series model would allow prediction to be made accurately. This research was carried out to find the best time series model to predict the PM10 concentrations in Nilai, Negeri Sembilan, Malaysia. By considering two seasons which is wet season (north east monsoon and dry season (south west monsoon, seasonal autoregressive integrated moving average model were used to find the most suitable model to predict the PM10 concentrations in Nilai, Negeri Sembilan by using three error measures. Based on AIC statistics, results show that ARIMA (1, 1, 1 × (1, 0, 012 is the most suitable model to predict PM10 concentrations in Nilai, Negeri Sembilan.

  14. Short-time regularity assessment of fibrillatory waves from the surface ECG in atrial fibrillation

    International Nuclear Information System (INIS)

    Alcaraz, Raúl; Martínez, Arturo; Hornero, Fernando; Rieta, José J

    2012-01-01

    This paper proposes the first non-invasive method for direct and short-time regularity quantification of atrial fibrillatory (f) waves from the surface ECG in atrial fibrillation (AF). Regularity is estimated by computing individual morphological variations among f waves, which are delineated and extracted from the atrial activity (AA) signal, making use of an adaptive signed correlation index. The algorithm was tested on real AF surface recordings in order to discriminate atrial signals with different organization degrees, providing a notably higher global accuracy (90.3%) than the two non-invasive AF organization estimates defined to date: the dominant atrial frequency (70.5%) and sample entropy (76.1%). Furthermore, due to its ability to assess AA regularity wave to wave, the proposed method is also able to pursue AF organization time course more precisely than the aforementioned indices. As a consequence, this work opens a new perspective in the non-invasive analysis of AF, such as the individualized study of each f wave, that could improve the understanding of AF mechanisms and become useful for its clinical treatment. (paper)

  15. Polynomial Phase Estimation Based on Adaptive Short-Time Fourier Transform.

    Science.gov (United States)

    Jing, Fulong; Zhang, Chunjie; Si, Weijian; Wang, Yu; Jiao, Shuhong

    2018-02-13

    Polynomial phase signals (PPSs) have numerous applications in many fields including radar, sonar, geophysics, and radio communication systems. Therefore, estimation of PPS coefficients is very important. In this paper, a novel approach for PPS parameters estimation based on adaptive short-time Fourier transform (ASTFT), called the PPS-ASTFT estimator, is proposed. Using the PPS-ASTFT estimator, both one-dimensional and multi-dimensional searches and error propagation problems, which widely exist in PPSs field, are avoided. In the proposed algorithm, the instantaneous frequency (IF) is estimated by S-transform (ST), which can preserve information on signal phase and provide a variable resolution similar to the wavelet transform (WT). The width of the ASTFT analysis window is equal to the local stationary length, which is measured by the instantaneous frequency gradient (IFG). The IFG is calculated by the principal component analysis (PCA), which is robust to the noise. Moreover, to improve estimation accuracy, a refinement strategy is presented to estimate signal parameters. Since the PPS-ASTFT avoids parameter search, the proposed algorithm can be computed in a reasonable amount of time. The estimation performance, computational cost, and implementation of the PPS-ASTFT are also analyzed. The conducted numerical simulations support our theoretical results and demonstrate an excellent statistical performance of the proposed algorithm.

  16. Multifractals embedded in short time series: An unbiased estimation of probability moment

    Science.gov (United States)

    Qiu, Lu; Yang, Tianguang; Yin, Yanhua; Gu, Changgui; Yang, Huijie

    2016-12-01

    An exact estimation of probability moments is the base for several essential concepts, such as the multifractals, the Tsallis entropy, and the transfer entropy. By means of approximation theory we propose a new method called factorial-moment-based estimation of probability moments. Theoretical prediction and computational results show that it can provide us an unbiased estimation of the probability moments of continuous order. Calculations on probability redistribution model verify that it can extract exactly multifractal behaviors from several hundred recordings. Its powerfulness in monitoring evolution of scaling behaviors is exemplified by two empirical cases, i.e., the gait time series for fast, normal, and slow trials of a healthy volunteer, and the closing price series for Shanghai stock market. By using short time series with several hundred lengths, a comparison with the well-established tools displays significant advantages of its performance over the other methods. The factorial-moment-based estimation can evaluate correctly the scaling behaviors in a scale range about three generations wider than the multifractal detrended fluctuation analysis and the basic estimation. The estimation of partition function given by the wavelet transform modulus maxima has unacceptable fluctuations. Besides the scaling invariance focused in the present paper, the proposed factorial moment of continuous order can find its various uses, such as finding nonextensive behaviors of a complex system and reconstructing the causality relationship network between elements of a complex system.

  17. Two Machine Learning Approaches for Short-Term Wind Speed Time-Series Prediction.

    Science.gov (United States)

    Ak, Ronay; Fink, Olga; Zio, Enrico

    2016-08-01

    The increasing liberalization of European electricity markets, the growing proportion of intermittent renewable energy being fed into the energy grids, and also new challenges in the patterns of energy consumption (such as electric mobility) require flexible and intelligent power grids capable of providing efficient, reliable, economical, and sustainable energy production and distribution. From the supplier side, particularly, the integration of renewable energy sources (e.g., wind and solar) into the grid imposes an engineering and economic challenge because of the limited ability to control and dispatch these energy sources due to their intermittent characteristics. Time-series prediction of wind speed for wind power production is a particularly important and challenging task, wherein prediction intervals (PIs) are preferable results of the prediction, rather than point estimates, because they provide information on the confidence in the prediction. In this paper, two different machine learning approaches to assess PIs of time-series predictions are considered and compared: 1) multilayer perceptron neural networks trained with a multiobjective genetic algorithm and 2) extreme learning machines combined with the nearest neighbors approach. The proposed approaches are applied for short-term wind speed prediction from a real data set of hourly wind speed measurements for the region of Regina in Saskatchewan, Canada. Both approaches demonstrate good prediction precision and provide complementary advantages with respect to different evaluation criteria.

  18. Long Short-Term Memory Neural Networks for Online Disturbance Detection in Satellite Image Time Series

    Directory of Open Access Journals (Sweden)

    Yun-Long Kong

    2018-03-01

    Full Text Available A satellite image time series (SITS contains a significant amount of temporal information. By analysing this type of data, the pattern of the changes in the object of concern can be explored. The natural change in the Earth’s surface is relatively slow and exhibits a pronounced pattern. Some natural events (for example, fires, floods, plant diseases, and insect pests and human activities (for example, deforestation and urbanisation will disturb this pattern and cause a relatively profound change on the Earth’s surface. These events are usually referred to as disturbances. However, disturbances in ecosystems are not easy to detect from SITS data, because SITS contain combined information on disturbances, phenological variations and noise in remote sensing data. In this paper, a novel framework is proposed for online disturbance detection from SITS. The framework is based on long short-term memory (LSTM networks. First, LSTM networks are trained by historical SITS. The trained LSTM networks are then used to predict new time series data. Last, the predicted data are compared with real data, and the noticeable deviations reveal disturbances. Experimental results using 16-day compositions of the moderate resolution imaging spectroradiometer (MOD13Q1 illustrate the effectiveness and stability of the proposed approach for online disturbance detection.

  19. Rotor-System Log-Decrement Identification Using Short-Time Fourier-Transform Filter

    Directory of Open Access Journals (Sweden)

    Qihang Li

    2015-01-01

    Full Text Available With the increase of the centrifugal compressor capability, such as large scale LNG and CO2 reinjection, the stability margin evaluation is crucial to assure the compressor work in the designed operating conditions in field. Improving the precision of parameter identification of stability is essential and necessary as well. Based on the time-varying characteristics of response vibration during the sine-swept process, a short-time Fourier transform (STFT filter was introduced to increase the signal-noise ratio and improve the accuracy of the estimated stability parameters. A finite element model was established to simulate the sine-swept process, and the simulated vibration signals were used to study the filtering effect and demonstrate the feasibility to identify the stability parameters by using Multiple-Input and Multiple-Output system identification method that combines the prediction error method and instrumental variable method. Simulation results show that the identification method with STFT filter improves the estimated accuracy much well and makes the curves of frequency response function clearer. Experiment was carried out on a test rig as well, which indicates the identification method is feasible in stability identification, and the results of experiment indicate that STFT filter works very well.

  20. Timing of introduction of complementary food: short- and long-term health consequences.

    Science.gov (United States)

    Przyrembel, Hildegard

    2012-01-01

    Complementary food is needed when breast milk (or infant formula) alone is no longer sufficient for both nutritional and developmental reasons. The timing of its introduction, therefore, is an individual decision, although 6 months of exclusive breastfeeding can be recommended for most healthy term infants. The new foods are intended to 'complement' ongoing breastfeeding with those dietary items whose intake has become marginal or insufficient. Both breastfeeding and complementary feeding can have direct or later consequences on health. The evaluation of consequences of both early and late introduction of complementary food can neither disregard the effect of breastfeeding compared to formula feeding nor the composition or quality of the complementary food. Possible short-term health effects concern growth velocity and infections, and possible long-term effects may relate to atopic diseases, type 1 and 2 diabetes, obesity and neuromuscular development. On the basis of the currently available evidence, it is impossible to exactly determine the age when risks related to the start of complementary feeding are lowest or highest for most of these effects, with the possible exception of infections and early growth velocity. The present knowledge on undesirable health effects, however, is mainly based on observational studies, and although some mechanisms have been proposed, further prospective studies have to clarify these unsolved issues. Even less evidence on the consequences of the timing of complementary food introduction is available for formula-fed infants. Copyright © 2012 S. Karger AG, Basel.

  1. Influence of Short-time Oxidation on Corrosion Properties of Directionally Solidified Superalloys with Different Orientations

    Directory of Open Access Journals (Sweden)

    MA Luo-ning

    2016-07-01

    Full Text Available In order to investigate the corrosion performance on intersecting and longitudinal surfaces of unoxidized and oxidized directionally solidified superalloys, Ni-base directionally solidified superalloy DZ125 and Co-base directionally solidified superalloy DZ40M were selected. Oxidation behavior on both alloys with different orientations was investigated at 1050℃ at different times, simulating the oxidation process of vanes or blades in service; subsequent electrochemical performance in 3.5%NaCl aqueous solution was studied on two orientations of unoxidized and oxidized alloys, simulating the corrosion process of superalloy during downtime. The results show that grain boundaries and sub-boundaries of directionally solidified superalloys are susceptible to corrosion and thus longitudinal surface with lower area fraction of grain boundaries has higher corrosion resistance. Compared to intersecting surface of alloys, the structure of grain boundaries of longitudinal surface is less conducive to diffusion and thus the oxidation rate on longitudinal surface is lower. Formation of oxide layers on alloys after short-time oxidation provides protective effect and enhances the corrosion resistance.

  2. Incorporating geostrophic wind information for improved space–time short-term wind speed forecasting

    KAUST Repository

    Zhu, Xinxin

    2014-09-01

    Accurate short-term wind speed forecasting is needed for the rapid development and efficient operation of wind energy resources. This is, however, a very challenging problem. Although on the large scale, the wind speed is related to atmospheric pressure, temperature, and other meteorological variables, no improvement in forecasting accuracy was found by incorporating air pressure and temperature directly into an advanced space-time statistical forecasting model, the trigonometric direction diurnal (TDD) model. This paper proposes to incorporate the geostrophic wind as a new predictor in the TDD model. The geostrophic wind captures the physical relationship between wind and pressure through the observed approximate balance between the pressure gradient force and the Coriolis acceleration due to the Earth’s rotation. Based on our numerical experiments with data from West Texas, our new method produces more accurate forecasts than does the TDD model using air pressure and temperature for 1to 6-hour-ahead forecasts based on three different evaluation criteria. Furthermore, forecasting errors can be further reduced by using moving average hourly wind speeds to fit the diurnal pattern. For example, our new method obtains between 13.9% and 22.4% overall mean absolute error reduction relative to persistence in 2-hour-ahead forecasts, and between 5.3% and 8.2% reduction relative to the best previous space-time methods in this setting.

  3. Severe symptoms of short tear break-up time dry eye are associated with accommodative microfluctuations

    Directory of Open Access Journals (Sweden)

    Kaido M

    2017-05-01

    Full Text Available Minako Kaido,1,2 Motoko Kawashima,1 Reiko Ishida,1,3 Kazuo Tsubota1 1Department of Ophthalmology, Keio University School of Medicine, Tokyo, 2Wada Eye Clinic, Chiba, 3Ishida Eye Clinic, Shizuoka, Japan Aim: Validating the hypothesis that accommodative microfluctuations (AMFs may be associated with severe symptoms in short tear break-up time (BUT dry eye (DE. Methods: This study included 12 subjects with short BUT DE (age: 49.6±18.3 years. Diagnoses were performed based on the presence of DE symptoms, BUT ≤5 s, Schirmer score >5 mm, and negative keratoconjunctival epithelial damage. Tear evaluation, AMF, and functional visual acuity (VA examinations were conducted before and after DE treatment. The AMF parameters evaluated were: total high-frequency component (HFC, HFC with low accommodation for the task of staring into the distance (HFC1, HFC with high accommodation for deskwork (HFC2. A subjective questionnaire of DE symptoms was also performed. Results: Mean BUT increased from 1.9±2.0 to 6.4±2.5 s after treatment (P<0.05. The mean logarithm of the minimum angle of resolution functional VA significantly improved (from 0.19±0.19 to 0.12±0.17; P<0.05. Mean power spectrum values for total HFC and HFC1 decreased (from 61.3±5.7 to 53.8±6.6 dB and from 62.9±10.5 to 52.4±6.2 dB, respectively; P<0.05, while the mean HFC2 power spectrum values did not differ before and after treatment (P>0.05. Subjective DE symptoms were reduced in nine patients. Conclusion: Along with the improvement of BUT after treatment, DE symptoms diminished and HFC1 and functional VA improved, suggesting that tear film instability is associated with deterioration of functional VA, AMF, and DE symptoms. Keywords: accommodative microfluctuation, ciliary muscle spasm, dry eye, ocular fatigue, tear break-up time, functional visual acuity 

  4. Time Course Changes in Selected Biochemical Stress Indices in Broilers Exposed to Short-term Noise

    Directory of Open Access Journals (Sweden)

    Iveta Bedáňová

    2010-01-01

    Full Text Available Time course changes in selected biochemical stress indices (corticosterone, triglycerides, glucose, cholesterol following short-term noise exposure at 100 dB for 28 min were studied in broilers aged 42 days. Corticosterone concentrations were found to increase during the first 10 min of noise exposure and to differ significantly from the control (background sound – 50 dB at Time 10 min and 14 min, then decreased continually and at 28 min returned to the initial prestress value. Triglyceride concentrations increased in broilers exposed to 100 dB noise during the first 12 min with a significant difference from the control at 12 min and 14 min. Glucose concentrations were higher due to 100 dB noise exposure for almost the entire period monitored, with significant differences between 100 dB and control broilers at 6 min and from 10 min to 14 min. Similarly as for the corticosterone concentration, a drop in triglycerides and glucose concentrations was seen approximately from Time 14 min and a return to the pre-stress value at 28 min. The cholesterol concentrations showed various temporal patterns with no significant difference between 100 dB and control broilers in this experiment. The pattern of response found in the study indicates that 100 dB noise represents a stress factor in broilers, however, there is the ability of broilers to adapt to an increased level of noise at this intensity after the first 14 min of exposure. The findings obtained in the study may contribute to expanding detailed knowledge of physiological stress responses to this specific noise stimulus in poultry, and could thereby be used to improve the welfare of broilers in intensive housing systems.

  5. Short communication. Harvest time in hedgerow Arbequina olive orchards in areas with early frosts

    Energy Technology Data Exchange (ETDEWEB)

    Gracia, P.; Sanchez-Gimeno, A. C.; Benito, M.; Oria, R.; Lasa, J. M.

    2012-11-01

    The shortening of harvest time attained in hedgerow olive (Olea europaea L.) orchards represents an advantage for the adoption of this cropping system in areas that are prone to suffer frost during the harvest period. To establish an optimal harvesting window, we carried out a study of the fruit ripening process on a hedgerow orchard of Arbequina olive trees, located in Zaragoza (Spain). From 2007 to 2009, oil accumulation on the fruit (% of dry weight) and oil yield (grams of oil per 100 fruits) were monitored, from early September to late November. Over the three years both variables peaked around November 15th, indicating that Arbequina reached full ripening earlier than has been reported previously for this variety. In two of the three seasons the orchard suffered several frosts during November. Long term climatic data from this area indicated that the risk of early frosts (< -2 degree centigrade) increases as November progresses with a high risk after November 20{sup t}h. In conclusion, the optimal harvesting period for Arbequina in this area should not extend beyond November 20{sup t}h. A rapid harvesting before this date is advisable to avoid the risk of damage caused by early frost in Zaragoza. Hedgerow planting provides an additional advantage in frost-prone areas, because mechanization of operations permits a short harvest period, easier to fit into the optimal harvesting window. (Author) 20 refs.

  6. Short-term visual memory for location in depth: A U-shaped function of time.

    Science.gov (United States)

    Reeves, Adam; Lei, Quan

    2017-10-01

    Short-term visual memory was studied by displaying arrays of four or five numerals, each numeral in its own depth plane, followed after various delays by an arrow cue shown in one of the depth planes. Subjects reported the numeral at the depth cued by the arrow. Accuracy fell with increasing cue delay for the first 500 ms or so, and then recovered almost fully. This dipping pattern contrasts with the usual iconic decay observed for memory traces. The dip occurred with or without a verbal or color-shape retention load on working memory. In contrast, accuracy did not change with delay when a tonal cue replaced the arrow cue. We hypothesized that information concerning the depths of the numerals decays over time in sensory memory, but that cued recall is aided later on by transfer to a visual memory specialized for depth. This transfer is sufficiently rapid with a tonal cue to compensate for the sensory decay, but it is slowed by the need to tag the arrow cue's depth relative to the depths of the numerals, exposing a dip when sensation has decayed and transfer is not yet complete. A model with a fixed rate of sensory decay and varied transfer rates across individuals captures the dip as well as the cue modality effect.

  7. Thermal sterilization of heat-sensitive products using high-temperature short-time sterilization.

    Science.gov (United States)

    Mann, A; Kiefer, M; Leuenberger, H

    2001-03-01

    High-temperature short-time (HTST) sterilization with a continuous-flow sterilizer, developed for this study, was evaluated. The evaluation was performed with respect to (a) the chemical degradation of two heat-sensitive drugs in HTST range (140-160 degrees C) and (b) the microbiological effect of HTST sterilization. Degradation kinetics of two heat-sensitive drugs showed that a high peak temperature sterilization process resulted in less chemical degradation for the same microbiological effect than a low peak temperature process. Both drugs investigated could be sterilized with acceptable degradation at HTST conditions. For the evaluation of the microbiological effect, Bacillus stearothermophilus ATCC 7953 spores were used as indicator bacteria. Indicator spore kinetics (D(T), z value, k, and E(a)), were determined in the HTST range. A comparison between the Bigelow model (z value concept) and the Arrhenius model, used to describe the temperature coefficient of the microbial inactivation, demonstrated that the Bigelow model is more accurate in prediction of D(T) values in the HTST range. The temperature coefficient decreased with increasing temperature. The influence of Ca(2+) ions and pH value on the heat resistance of the indicator spores, which is known under typical sterilization conditions, did not change under HTST conditions.

  8. Effectiveness of mouse minute virus inactivation by high temperature short time treatment technology: a statistical assessment.

    Science.gov (United States)

    Murphy, Marie; Quesada, Guillermo Miro; Chen, Dayue

    2011-11-01

    Viral contamination of mammalian cell cultures in GMP manufacturing facility represents a serious safety threat to biopharmaceutical industry. Such adverse events usually require facility shutdown for cleaning/decontamination, and thus result in significant loss of production and/or delay of product development. High temperature short time (HTST) treatment of culture media has been considered as an effective method to protect GMP facilities from viral contaminations. Log reduction factor (LRF) has been commonly used to measure the effectiveness of HTST treatment for viral inactivation. However, in order to prevent viral contaminations, HTST treatment must inactivate all infectious viruses (100%) in the medium batch since a single virus is sufficient to cause contamination. Therefore, LRF may not be the most appropriate indicator for measuring the effectiveness of HTST in preventing viral contaminations. We report here the use of the probability to achieve complete (100%) virus inactivation to assess the effectiveness of HTST treatment. By using mouse minute virus (MMV) as a model virus, we have demonstrated that the effectiveness of HTST treatment highly depends upon the level of viral contaminants in addition to treatment temperature and duration. We believe that the statistical method described in this report can provide more accurate information about the power and potential limitation of technologies such as HTST in our shared quest to mitigate the risk of viral contamination in manufacturing facilities. Copyright © 2011 The International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

  9. Mechanical Properties, Short Time Creep, and Fatigue of an Austenitic Steel

    Directory of Open Access Journals (Sweden)

    Josip Brnic

    2016-04-01

    Full Text Available The correct choice of a material in the process of structural design is the most important task. This study deals with determining and analyzing the mechanical properties of the material, and the material resistance to short-time creep and fatigue. The material under consideration in this investigation is austenitic stainless steel X6CrNiTi18-10. The results presenting ultimate tensile strength and 0.2 offset yield strength at room and elevated temperatures are displayed in the form of engineering stress-strain diagrams. Besides, the creep behavior of the steel is presented in the form of creep curves. The material is consequently considered to be creep resistant at temperatures of 400 °C and 500 °C when subjected to a stress which is less than 0.9 of the yield strength at the mentioned temperatures. Even when the applied stress at a temperature of 600 °C is less than 0.5 of the yield strength, the steel may be considered as resistant to creep. Cyclic tensile fatigue tests were carried out at stress ratio R = 0.25 using a servo-pulser machine and the results were recorded. The analysis shows that the stress level of 434.33 MPa can be adopted as a fatigue limit. The impact energy was also determined and the fracture toughness assessed.

  10. Cerebral blood flow measurement using stable xenon CT with very short inhalation times

    Energy Technology Data Exchange (ETDEWEB)

    Touho, Hajime; Karasawa, Jun; Shishido, Hisashi; Yamada, Keisuke; Shibamoto, Keiji [Osaka Neurological Inst., Toyonaka (Japan)

    1991-02-01

    A noninvasive, simplified method using inhalation of stable xenon (Xe{sup s}) and computed tomographic (CT) scanning to estimate regional cerebral blood flow (rCBF) and regional partition coefficient (r{lambda}) is described. Twenty-four patients with cerebrovascular occlusive disease and six volunteer controls inhaled 30% Xe{sup s} and 70% oxygen for 180 seconds and exhaled for 144 seconds during serial CT scanning without denitrogenation. The end-tidal Xe{sup s} concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) for arteries with the curve fitting method. The time-CT number (Hounsfield unit) curve for cerebral tissue during the Xe{sup s} washin and washout phases was used to calculate r{lambda} and rCBF using least squares curve fitting analysis. The resultant r{lambda} and rCBF map demonstrated a reliable distribution between the gray and white matter, and infarcted areas. rCBF was high in gray matter, low in white matter, and much lower in infarcted areas than in white matter. r{lambda} was high in white matter, low in gray matter, and much lower in infarcted areas. Xe{sup s} CT-CBF studies with very short inhalation of 180 seconds is a clinically useful method for evaluation of rCBF in patients with cerebrovascular diseases. (author).

  11. Forecast of electric power market to short-term: a time series approcah

    International Nuclear Information System (INIS)

    Costa, Roberio Neves Pelinca da.

    1994-01-01

    Three different time series approaches are analysed by this dissertation in the Brazilian electricity markert context. The aim is to compare the predictive performance of these approaches from a simulated exercise using the main series of the Brazilian consumption of electricity: Total Consumption, Industrial Consumption, Residencial Consumption and Commercial Consumption. One concludes that these appraches offer an enormous potentiality to the short-term planning system of the Electric Sector. Among the univariate models, the results for the analysed period point out that the forecast produced by Holt-Winter's models are more accurate than those produced by ARIMA and structural models. When explanatory variables are introduced in the last models, one can notice, in general, an improvement in the predictive performance of the models, although there is no sufficient evidence to consider that they are superior to Holt-Winter's models. The models with explanatory variables can be particularly useful, however, when one intends either to build scenarios or to study the effects of some variables on the consumption of electricity. (author). 73 refs., 19 figs., 13 tabs

  12. Application of MOSFET detectors for dosimetry in small animal radiography using short exposure times.

    Science.gov (United States)

    De Lin, Ming; Toncheva, Greta; Nguyen, Giao; Kim, Sangroh; Anderson-Evans, Colin; Johnson, G Allan; Yoshizumi, Terry T

    2008-08-01

    Digital subtraction angiography (DSA) X-ray imaging for small animals can be used for functional phenotyping given its ability to capture rapid physiological changes at high spatial and temporal resolution. The higher temporal and spatial requirements for small-animal imaging drive the need for short, high-flux X-ray pulses. However, high doses of ionizing radiation can affect the physiology. The purpose of this study was to verify and apply metal oxide semiconductor field effect transistor (MOSFET) technology to dosimetry for small-animal diagnostic imaging. A tungsten anode X-ray source was used to expose a tissue-equivalent mouse phantom. Dose measurements were made on the phantom surface and interior. The MOSFETs were verified with thermoluminescence dosimeters (TLDs). Bland-Altman analysis showed that the MOSFET results agreed with the TLD results (bias, 0.0625). Using typical small animal DSA scan parameters, the dose ranged from 0.7 to 2.2 cGy. Application of the MOSFETs in the small animal environment provided two main benefits: (1) the availability of results in near real-time instead of the hours needed for TLD processes and (2) the ability to support multiple exposures with different X-ray techniques (various of kVp, mA and ms) using the same MOSFET. This MOSFET technology has proven to be a fast, reliable small animal dosimetry method for DSA imaging and is a good system for dose monitoring for serial and gene expression studies.

  13. Fecal short-chain fatty acids at different time points after ceftriaxone administration in rats

    Directory of Open Access Journals (Sweden)

    Yu. V. Holota

    2017-02-01

    Full Text Available Short-chain fatty acids (SCFAs are major products of the microbial fermentation of dietary fiber in the colon. Recent studies suggest that these products of microbial metabolism in the gut act as signaling molecules, influence host energy homeostasis and play major immunological roles. In the present study, defined the long-term effects of ceftriaxone administration on the fecal SCFAs concentration in Wistar rats. Ceftriaxone (300 mg/kg, i.m. was administered daily for 14 days. Rats were euthanized in 1, 15 and 56 days after ceftriaxone withdrawal. Caecal weight and fecal concentration of SCFAs by gas chromatography were measured. Ceftriaxone administration induced time-dependent rats’ caecal enlargement through accumulation of undigestable substances. In 1 day after ceftriaxone withdrawal, the concentrations of acetic, propionic, butyric acids and total SCFAs were decreased 2.9-, 13.8-, 8.5-, 4.8-fold (P < 0.05, respectively. Concentration of valeric, isovaleric and caproic acids was below the detectable level. That was accompanied by decreased 4.3-fold anaerobic index and increased the relative amount of acetic acid (P < 0.05. In 56 days, concentration of SCFAs was still below control value but higher than in 1 day (except propionic acid. Anaerobic index was lower 1.3-fold (P < 0.05 vs. control. Conclusion: antibiotic therapy induced long-term disturbance in colonic microbiota metabolic activity.

  14. Improvement of the Original Isolation Procedure for Hormone Studies in Short-Time Culture

    Directory of Open Access Journals (Sweden)

    Mukadder Atmaca

    2005-01-01

    Full Text Available Earlier studies indicated that hormone responsiveness of cells and metabolic activity was lost during various of experimental procedure. In the light of this observation, I aimed to investigate to obtain optimal conditions for short time cultured hepatocytes and also to determine the type of test can be used to evaluate suitablity of hepatocytes for hormones studies. During the isolation period 50 IU/ml and 100 IU/ml collagenase were used. Adrenaline (10-6M was used to measure sensitivity of hepatocytes to hormones and glycogenolsis was measured at the end of 2hr incubation period. Adrenaline significantly increased gylcogenolysis (Control: 0.16±0.01 mg/2hr; Adrenaline: 0.30±0.01 mg/2hr only when the 50 IU/ml collagenase was used and the viability of the cells were over 95%. Viability tests were applied to hepatocytes that obtained by using 50 IU collagenase. Cellular glutathione, methylthiazoltetrazolium reduction, lactatedehdrogenase leakage, ATP level measured to determine viability following the attachment and incubation period. No differences were observed at the end of each period.Altogether, the present study indicated that membrane integrity and metabolic function of the hepatocytes can be improved by modifying slightly the original procedure of Reese and Byard.

  15. Mechanical Properties, Short Time Creep, and Fatigue of an Austenitic Steel.

    Science.gov (United States)

    Brnic, Josip; Turkalj, Goran; Canadija, Marko; Lanc, Domagoj; Krscanski, Sanjin; Brcic, Marino; Li, Qiang; Niu, Jitai

    2016-04-20

    The correct choice of a material in the process of structural design is the most important task. This study deals with determining and analyzing the mechanical properties of the material, and the material resistance to short-time creep and fatigue. The material under consideration in this investigation is austenitic stainless steel X6CrNiTi18-10. The results presenting ultimate tensile strength and 0.2 offset yield strength at room and elevated temperatures are displayed in the form of engineering stress-strain diagrams. Besides, the creep behavior of the steel is presented in the form of creep curves. The material is consequently considered to be creep resistant at temperatures of 400 °C and 500 °C when subjected to a stress which is less than 0.9 of the yield strength at the mentioned temperatures. Even when the applied stress at a temperature of 600 °C is less than 0.5 of the yield strength, the steel may be considered as resistant to creep. Cyclic tensile fatigue tests were carried out at stress ratio R = 0.25 using a servo-pulser machine and the results were recorded. The analysis shows that the stress level of 434.33 MPa can be adopted as a fatigue limit. The impact energy was also determined and the fracture toughness assessed.

  16. Measurement of short transverse relaxation times by pseudo-echo nutation experiments

    Science.gov (United States)

    Ferrari, Maude; Moyne, Christian; Canet, Daniel

    2018-07-01

    Very short NMR transverse relaxation times may be difficult to measure by conventional methods. Nutation experiments constitute an alternative approach. Nutation is, in the rotating frame, the equivalent of precession in the laboratory frame. It consists in monitoring the rotation of magnetization around the radio-frequency (rf) field when on-resonance conditions are fulfilled. Depending on the amplitude of the rf field, nutation may be sensitive to the two relaxation rates R1 and R2. A full theoretical development has been worked out for demonstrating how these two relaxation rates could be deduced from a simple nutation experiment, noticing however that inhomogeneity of the rf field may lead to erroneous results. This has led us to devise new experiments which are the equivalent of echo techniques in the rotating frame (pseudo spin-echo nutation experiment and pseudo gradient-echo experiment). Full equations of motion have been derived. Although complicated, they indicate that the sum of the two relaxation rates can be obtained very accurately and not altered by rf field inhomogeneity. This implies however an appropriate data processing accounting for the oscillations which are superposed to the echo decays and, anyway, theoretically predicted. A series of experiments has been carried out for different values of the rf field amplitude on samples of water doped with a paramagnetic compound at different concentrations. Pragmatically, as R1 can be easily measured by conventional methods, its value is entered in the data processing algorithm which then returns exclusively the value of the transverse relaxation time. Very consistent results are obtained that way.

  17. INFLUENCE OF RAMADAN FASTING ON ANAEROBIC PERFORMANCE AND RECOVERY FOLLOWING SHORT TIME HIGH INTENSITY EXERCISE

    Directory of Open Access Journals (Sweden)

    Umid Karli

    2007-12-01

    Full Text Available The aim of this study was to investigate the effects of Ramadan fasting on anaerobic power and capacity and the removal rate of lactate after short time high intensity exercise in power athletes. Ten male elite power athletes (2 wrestlers, 7 sprinters and 1 thrower, aged 20-24 yr, mean age 22.30 ± 1.25 yr participated in this study. The subjects were tested three times [3 days before the beginning of Ramadan (Pre-RF, the last 3 days of Ramadan (End-RF and the last 3 days of the 4th week after the end of Ramadan (After-RF]. Anaerobic power and capacity were measured by using the Wingate Anaerobic Test (WAnT at Pre-RF, End-RF and After- RF. Capillary blood samples for lactate analyses and heart rate recordings were taken at rest, immediately after WAnT and throughout the recovery period. Repeated measures of ANOVA indicated that there were no significant changes in body weight, body mass index, fat free mass, percentage of body fat, daily sleeping time and daily caloric intake associated with Ramadan fasting. No significant changes were found in total body water either, but urinary density measured at End-RF was significantly higher than After-RF. Similarity among peak HR and peak LA values at Pre-RF, End- RF and After-RF demonstrated that cardiovascular and metabolic stress caused by WAnT was not affected by Ramadan fasting. In addition, no influence of Ramadan fasting on anaerobic power and capacity and removal rate of LA from blood following high intensity exercise was observed. The results of this study revealed that if strength-power training is performed regularly and daily food intake, body fluid balance and daily sleeping time are maintained as before Ramadan, Ramadan fasting will not have adverse effects on body composition, anaerobic power and capacity, and LA metabolism during and after high intensity exercise in power athletes

  18. Time-Based Loss in Visual Short-Term Memory Is from Trace Decay, Not Temporal Distinctiveness

    Science.gov (United States)

    Ricker, Timothy J.; Spiegel, Lauren R.; Cowan, Nelson

    2014-01-01

    There is no consensus as to why forgetting occurs in short-term memory tasks. In past work, we have shown that forgetting occurs with the passage of time, but there are 2 classes of theories that can explain this effect. In the present work, we investigate the reason for time-based forgetting by contrasting the predictions of temporal…

  19. [Possibilities in the differential diagnosis of brain neoplasms using the long and short time sequences of proton magnetic resonance spectroscopy

    NARCIS (Netherlands)

    Gajewicz, W.; Goraj, B.M.

    2004-01-01

    Currently to perform proton magnetic resonance spectroscopy (1H MRS) with single voxel spectroscopy (SVS) technique long and/or short echo time sequences are used in order to provide complementary information. PURPOSE: The aim of the study was to compare the usefulness of STEAM (time echo, TE, 20

  20. The big fix : fresh thinking on turnarounds could reduce downtime and costs

    International Nuclear Information System (INIS)

    Stastny, P.

    2007-01-01

    Major overhauls at oilsands processing plants were discussed. The harsh chemicals and abrasive substances used to process and refine bitumens are responsible for most of the major maintenance turnarounds required at oilsands plants. Catastrophic failures can often result in the decision to shut a plant down entirely and proceed with overhauls scheduled in the future. Control equipment is often replaced during turnarounds to further optimize processing capabilities, and many oilsands operators are now including turnarounds in their labour forecasts in order to more effectively manage their maintenance workforce. Unexpected maintenance requirements can often make planning for turnarounds problematic. Complex decision-making is often needed to balance both maintenance budgets and schedules. While many major operators are still directly managing managing turnarounds, other operators are now contracting service companies to plan and oversee major maintenance overhauls. It was concluded that contracted maintenance work can allow service companies to invest in training and maintenance technologies that may help to ensure the smooth operation of oil sands processing plants. 4 figs

  1. Short-Time Structural Stability of Compressible Vortex Sheets with Surface Tension

    Science.gov (United States)

    Stevens, Ben

    2016-11-01

    Assume we start with an initial vortex-sheet configuration which consists of two inviscid fluids with density bounded below flowing smoothly past each other, where a strictly positive fixed coefficient of surface tension produces a surface tension force across the common interface, balanced by the pressure jump. We model the fluids by the compressible Euler equations in three space dimensions with a very general equation of state relating the pressure, entropy and density such that the sound speed is positive. We prove that, for a short time, there exists a unique solution of the equations with the same structure. The mathematical approach consists of introducing a carefully chosen artificial viscosity-type regularisation which allows one to linearise the system so as to obtain a collection of transport equations for the entropy, pressure and curl together with a parabolic-type equation for the velocity which becomes fairly standard after rotating the velocity according to the interface normal. We prove a high order energy estimate for the non-linear equations that is independent of the artificial viscosity parameter which allows us to send it to zero. This approach loosely follows that introduced by Shkoller et al. in the setting of a compressible liquid-vacuum interface. Although already considered by Coutand et al. [10] and Lindblad [17], we also make some brief comments on the case of a compressible liquid-vacuum interface, which is obtained from the vortex sheets problem by replacing one of the fluids by vacuum, where it is possible to obtain a structural stability result even without surface tension.

  2. Classification of brain tumours using short echo time 1H MR spectra

    Science.gov (United States)

    Devos, A.; Lukas, L.; Suykens, J. A. K.; Vanhamme, L.; Tate, A. R.; Howe, F. A.; Majós, C.; Moreno-Torres, A.; van der Graaf, M.; Arús, C.; Van Huffel, S.

    2004-09-01

    The purpose was to objectively compare the application of several techniques and the use of several input features for brain tumour classification using Magnetic Resonance Spectroscopy (MRS). Short echo time 1H MRS signals from patients with glioblastomas ( n = 87), meningiomas ( n = 57), metastases ( n = 39), and astrocytomas grade II ( n = 22) were provided by six centres in the European Union funded INTERPRET project. Linear discriminant analysis, least squares support vector machines (LS-SVM) with a linear kernel and LS-SVM with radial basis function kernel were applied and evaluated over 100 stratified random splittings of the dataset into training and test sets. The area under the receiver operating characteristic curve (AUC) was used to measure the performance of binary classifiers, while the percentage of correct classifications was used to evaluate the multiclass classifiers. The influence of several factors on the classification performance has been tested: L2- vs. water normalization, magnitude vs. real spectra and baseline correction. The effect of input feature reduction was also investigated by using only the selected frequency regions containing the most discriminatory information, and peak integrated values. Using L2-normalized complete spectra the automated binary classifiers reached a mean test AUC of more than 0.95, except for glioblastomas vs. metastases. Similar results were obtained for all classification techniques and input features except for water normalized spectra, where classification performance was lower. This indicates that data acquisition and processing can be simplified for classification purposes, excluding the need for separate water signal acquisition, baseline correction or phasing.

  3. Process configuration of Liquid-nitrogen Energy Storage System (LESS) for maximum turnaround efficiency

    Science.gov (United States)

    Dutta, Rohan; Ghosh, Parthasarathi; Chowdhury, Kanchan

    2017-12-01

    Diverse power generation sector requires energy storage due to penetration of variable renewable energy sources and use of CO2 capture plants with fossil fuel based power plants. Cryogenic energy storage being large-scale, decoupled system with capability of producing large power in the range of MWs is one of the options. The drawback of these systems is low turnaround efficiencies due to liquefaction processes being highly energy intensive. In this paper, the scopes of improving the turnaround efficiency of such a plant based on liquid Nitrogen were identified and some of them were addressed. A method using multiple stages of reheat and expansion was proposed for improved turnaround efficiency from 22% to 47% using four such stages in the cycle. The novelty here is the application of reheating in a cryogenic system and utilization of waste heat for that purpose. Based on the study, process conditions for a laboratory-scale setup were determined and presented here.

  4. Estimating return periods of extreme values from relatively short time series of winds

    Science.gov (United States)

    Jonasson, Kristjan; Agustsson, Halfdan; Rognvaldsson, Olafur; Arfeuille, Gilles

    2013-04-01

    An important factor for determining the prospect of individual wind farm sites is the frequency of extreme winds at hub height. Here, extreme winds are defined as the value of the highest 10 minutes averaged wind speed with a 50 year return period, i.e. annual exceeding probability of 2% (Rodrigo, 2010). A frequently applied method to estimate winds in the lowest few hundred meters above ground is to extrapolate observed 10-meter winds logarithmically to higher altitudes. Recent study by Drechsel et al. (2012) showed however that this methodology is not as accurate as interpolating simulated results from the global ECMWF numerical weather prediction (NWP) model to the desired height. Observations of persistent low level jets near Colima in SW-Mexico also show that the logarithmic approach can give highly inaccurate results for some regions (Arfeuille et al., 2012). To address these shortcomings of limited, and/or poorly representative, observations and extrapolations of winds one can use NWP models to dynamically scale down relatively coarse resolution atmospheric analysis. In the case of limited computing resources one has typically to make a compromise between spatial resolution and the duration of the simulated period, both of which can limit the quality of the wind farm siting. A common method to estimate maximum winds is to fit an extreme value distribution (e.g. Gumbel, gev or Pareto) to the maximum values of each year of available data, or the tail of these values. If data are only available for a short period, e.g. 10 or 15 years, then this will give a rather inaccurate estimate. It is possible to deal with this problem by utilizing monthly or weekly maxima, but this introduces new problems: seasonal variation, autocorrelation of neighboring values, and increased discrepancy between data and fitted distribution. We introduce a new method to estimate return periods of extreme values of winds at hub height from relatively short time series of winds, simulated

  5. Can the universe fragment into many independent causal patches at turnaround in cyclic cosmology?

    International Nuclear Information System (INIS)

    Zhang, Xin

    2009-01-01

    Infinitely cyclic cosmology is often frustrated by the second law of thermodynamics which dictates that the entropy increases from cycle to cycle so that extrapolation into the past will lead back to an initial singularity. It has been argued in the literature that the entropy problem can be resolved in a particular cyclic universe model through a deflation mechanism (i.e., the universe fragments into an astronomically large number of disconnected causal patches at the turnaround). We point out that in this cyclic model the Hubble distance will become infinity at the turnaround; thus the deflation scenario does not seem to be valid. (orig.)

  6. Construction of a flash-photolysis apparatus having a short discharge time

    International Nuclear Information System (INIS)

    Devillers, C.

    1964-01-01

    Flash photolysis aims at reaching directly the primary mechanisms resulting from the action of light on an absorbent matter. This makes it necessary to produce a flash as short and as bright as possible. Our main effort was directed towards reducing the duration of the flash by decreasing the self-inductance of the discharge circuit. A description of this circuit and study of the characteristics of the apparatus are followed by a short description of the two analytical methods: flash spectrography and absorption spectrophotometry at a given wave-length. (author) [fr

  7. Differences in the Policies, Programs, and Practices (PPPs) and Combination of PPPs across Turnaround, Moderately Improving, and Not Improving Schools

    Science.gov (United States)

    Herman, Rebecca; Huberman, Mette

    2012-01-01

    The TALPS study aims to build on the existing research base to develop promising methodologies to identify chronically low-performing and turnaround schools, as well as to identify promising strategies for turning around chronically low-performing schools. By looking specifically at schools identified as turnaround, in comparison to nonturnaround…

  8. "I've Never Seen People Work So Hard!" Teachers' Working Conditions in the Early Stages of School Turnaround

    Science.gov (United States)

    Cucchiara, Maia Bloomfield; Rooney, Erin; Robertson-Kraft, Claire

    2015-01-01

    School turnaround--a reform strategy that strives for quick and dramatic transformation of low-performing schools--has gained prominence in recent years. This study uses interviews and focus groups conducted with 86 teachers in 13 schools during the early stages of school turnaround in a large urban district to examine teachers' perceptions of the…

  9. Variational data assimilation for the optimized ozone initial state and the short-time forecasting

    Directory of Open Access Journals (Sweden)

    S.-Y. Park

    2016-03-01

    Full Text Available In this study, we apply the four-dimensional variational (4D-Var data assimilation to optimize initial ozone state and to improve the predictability of air quality. The numerical modeling systems used for simulations of atmospheric condition and chemical formation are the Weather Research and Forecasting (WRF model and the Community Multiscale Air Quality (CMAQ model. The study area covers the capital region of South Korea, where the surface measurement sites are relatively evenly distributed. The 4D-Var code previously developed for the CMAQ model is modified to consider background error in matrix form, and various numerical tests are conducted. The results are evaluated with an idealized covariance function for the appropriateness of the modified codes. The background error is then constructed using the NMC method with long-term modeling results, and the characteristics of the spatial correlation scale related to local circulation are analyzed. The background error is applied in the 4D-Var research, and a surface observational assimilation is conducted to optimize the initial concentration of ozone. The statistical results for the 12 h assimilation periods and the 120 observatory sites show a 49.4 % decrease in the root mean squared error (RMSE, and a 59.9 % increase in the index of agreement (IOA. The temporal variation of spatial distribution of the analysis increments indicates that the optimized initial state of ozone concentration is transported to inland areas by the clockwise-rotating local circulation during the assimilation windows. To investigate the predictability of ozone concentration after the assimilation window, a short-time forecasting is carried out. The ratios of the RMSE (root mean squared error with assimilation versus that without assimilation are 8 and 13 % for the +24 and +12 h, respectively. Such a significant improvement in the forecast accuracy is obtained solely by using the optimized initial state. The potential

  10. Technical Note: Deep learning based MRAC using rapid ultra-short echo time imaging.

    Science.gov (United States)

    Jang, Hyungseok; Liu, Fang; Zhao, Gengyan; Bradshaw, Tyler; McMillan, Alan B

    2018-05-15

    In this study, we explore the feasibility of a novel framework for MR-based attenuation correction for PET/MR imaging based on deep learning via convolutional neural networks, which enables fully automated and robust estimation of a pseudo CT image based on ultrashort echo time (UTE), fat, and water images obtained by a rapid MR acquisition. MR images for MRAC are acquired using dual echo ramped hybrid encoding (dRHE), where both UTE and out-of-phase echo images are obtained within a short single acquisition (35 sec). Tissue labeling of air, soft tissue, and bone in the UTE image is accomplished via a deep learning network that was pre-trained with T1-weighted MR images. UTE images are used as input to the network, which was trained using labels derived from co-registered CT images. The tissue labels estimated by deep learning are refined by a conditional random field based correction. The soft tissue labels are further separated into fat and water components using the two-point Dixon method. The estimated bone, air, fat, and water images are then assigned appropriate Hounsfield units, resulting in a pseudo CT image for PET attenuation correction. To evaluate the proposed MRAC method, PET/MR imaging of the head was performed on 8 human subjects, where Dice similarity coefficients of the estimated tissue labels and relative PET errors were evaluated through comparison to a registered CT image. Dice coefficients for air (within the head), soft tissue, and bone labels were 0.76±0.03, 0.96±0.006, and 0.88±0.01. In PET quantification, the proposed MRAC method produced relative PET errors less than 1% within most brain regions. The proposed MRAC method utilizing deep learning with transfer learning and an efficient dRHE acquisition enables reliable PET quantification with accurate and rapid pseudo CT generation. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  11. Application of Grey Model GM(1, 1) to Ultra Short-Term Predictions of Universal Time

    Science.gov (United States)

    Lei, Yu; Guo, Min; Zhao, Danning; Cai, Hongbing; Hu, Dandan

    2016-03-01

    A mathematical model known as one-order one-variable grey differential equation model GM(1, 1) has been herein employed successfully for the ultra short-term (advantage is that the developed method is easy to use. All these reveal a great potential of the GM(1, 1) model for UT1-UTC predictions.

  12. Cognitive Abilities Explaining Age-Related Changes in Time Perception of Short and Long Durations

    Science.gov (United States)

    Zelanti, Pierre S.; Droit-Volet, Sylvie

    2011-01-01

    The current study investigated how the development of cognitive abilities explains the age-related changes in temporal judgment over short and long duration ranges from 0.5 to 30 s. Children (5- and 9-year-olds) as well as adults were given a temporal bisection task with four different duration ranges: a duration range shorter than 1 s, two…

  13. Time Perspective and Identity Formation: Short-Term Longitudinal Dynamics in College Students

    Science.gov (United States)

    Luyckx, Koen; Lens, Willy; Smits, Ilse; Goossens, Luc

    2010-01-01

    Planning for the future and developing a personalized identity are conceived of as important developmental tasks that adolescents and emerging adults are confronted with on the pathway to adulthood. The present study set out to examine whether both tasks develop in tandem by using a short-term longitudinal dataset consisting of 371 college…

  14. Development of Speech Fluency over a Short Period of Time: Effects of Pedagogic Intervention

    Science.gov (United States)

    Tavakoli, Parvaneh; Campbell, Colin; McCormack, Joan

    2016-01-01

    This study investigates the effects of a short-term pedagogic intervention on development of second language (L2) fluency among learners studying English for academic purposes at a UK university. It also examines the interaction between development of fluency and complexity and accuracy. Through a pretest and posttest design, data were collected…

  15. The study of the possibility to use CAMEX chips in collider experiments with short bunch crossing time

    International Nuclear Information System (INIS)

    Aulchenko, V.M.; Chilingarov, A.G.; Serbo, V.V.; Titov, V.M.

    1993-01-01

    The study of the possibility to use CAMEX chips in several systems of the detector KEDR at the e + e - collider VEPP-4M was performed. The relatively short bunch crossing time at VEPP-4M 60 ns leads to some problems with the use of CAMEX in the standard mode. The different ways to overcome these difficulties are investigated and compared. (orig.)

  16. 25 CFR 26.30 - Does the Job Training Program provide part-time training or short-term training?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Does the Job Training Program provide part-time training or short-term training? 26.30 Section 26.30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES JOB PLACEMENT AND TRAINING PROGRAM Training Services § 26.30 Does the Job Training...

  17. Short echo time proton spectroscopy of the brain in healthy volunteers using an insert gradient head coil

    DEFF Research Database (Denmark)

    Gideon, P; Danielsen, E R; Schneider, M

    1995-01-01

    An insert gradient head coil with built-in X, Y, and Z gradients was used for localized proton spectroscopy in the brain of healthy volunteers, using short echo time stimulated echo acquisition mode (STEAM) sequences. Volume of interest size was 3.4 ml, repetition time was 6.0 s, and echo times...... were 10 and 20 ms, respectively. Good quality proton spectra with practically no eddy current artefacts were acquired allowing observation of strongly coupled compounds, and compounds with short T2 relaxation times. The gradient head coil thus permits further studies of compounds such as glutamine....../glutamate and myo-inositols. These compounds were more prominent within grey matter than within white matter. Rough estimations of metabolite concentrations using water as an internal standard were in good agreement with previous reports....

  18. Short-course versus long-course chemoradiation in rectal cancer--time to change strategies?

    Science.gov (United States)

    Palta, Manisha; Willett, Christopher G; Czito, Brian G

    2014-09-01

    There is significant debate regarding the optimal neoadjuvant regimen for resectable rectal cancer patients. Short-course radiotherapy, a standard approach throughout most of northern Europe, is generally defined as 25 Gy in 5 fractions over the course of 1 week without the concurrent administration of chemotherapy. Long-course radiotherapy is typically defined as 45 to 50.4 Gy in 25-28 fractions with the administration of concurrent 5-fluoropyrimidine-based chemotherapy and is the standard approach in other parts of Europe and the United States. At present, two randomized trials have compared outcomes for short course radiotherapy with long-course chemoradiation showing no difference in respective study endpoints. Late toxicity data are lacking given limited follow-up. Although the ideal neoadjuvant regimen is controversial, our current bias is long-course chemoradiation to treat patients with locally advanced, resectable rectal cancer.

  19. Age and admission times as predictive factors for failure of admissions to discharge-stream short-stay units.

    Science.gov (United States)

    Shetty, Amith L; Shankar Raju, Savitha Banagar; Hermiz, Arsalan; Vaghasiya, Milan; Vukasovic, Matthew

    2015-02-01

    Discharge-stream emergency short-stay units (ESSU) improve ED and hospital efficiency. Age of patients and time of hospital presentations have been shown to correlate with increasing complexity of care. We aim to determine whether an age and time cut-off could be derived to subsequently improve short-stay unit success rates. We conducted a retrospective audit on 6703 (5522 inclusions) patients admitted to our discharge-stream short-stay unit. Patients were classified as appropriate or inappropriate admissions, and deemed successful if discharged out of the unit within 24 h; and failures if they needed inpatient admission into the hospital. We calculated short-stay unit length of stay for patients in each of these groups. A 15% failure rate was deemed as acceptable key performance indicator (KPI) for our unit. There were 197 out of 4621 (4.3%, 95% CI 3.7-4.9%) patients up to the age of 70 who failed admission to ESSU compared with 67 out of 901 (7.4%, 95% CI 5.9-9.3%, P 70 years of age have higher rates of failure after admission to discharge-stream ESSU. Although in appropriately selected discharge-stream patients, no age group or time-band of presentation was associated with increased failure rate beyond the stipulated KPI. © 2014 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  20. Turnaround radius in an accelerated universe with quasi-local mass

    Energy Technology Data Exchange (ETDEWEB)

    Faraoni, Valerio; Lapierre-Léonard, Marianne; Prain, Angus, E-mail: vfaraoni@ubishops.ca, E-mail: mlapierre12@ubishops.ca, E-mail: angusprain@gmail.com [Physics Department, Bishop' s University, 2600 College Street, Sherbrooke, Québec, J1M 1Z7 Canada (Canada)

    2015-10-01

    We apply the Hawking-Hayward quasi-local energy construct to obtain in a rigorous way the turnaround radius of cosmic structures in General Relativity. A splitting of this quasi-local mass into local and cosmological parts describes the interplay between local attraction and cosmological expansion.

  1. Turnaround radius in an accelerated universe with quasi-local mass

    International Nuclear Information System (INIS)

    Faraoni, Valerio; Lapierre-Léonard, Marianne; Prain, Angus

    2015-01-01

    We apply the Hawking-Hayward quasi-local energy construct to obtain in a rigorous way the turnaround radius of cosmic structures in General Relativity. A splitting of this quasi-local mass into local and cosmological parts describes the interplay between local attraction and cosmological expansion

  2. CAD/CAM, Creativity, and Discipline Lead to Turnaround School Success

    Science.gov (United States)

    Gorman, Lynn

    2012-01-01

    Miami Central High School technology teacher Frank Houghtaling thinks the connection between theory and application is one reason his students perform better on the Florida Comprehensive Assessment Test (FCAT). The impressive turnaround school drew local and national attention last spring when one of Houghtaling's students, Dagoberto Cruz, won…

  3. Participatory Democracy and Struggling Schools: Making Space for Youth in School Turnarounds

    Science.gov (United States)

    Kirshner, Ben; Jefferson, Anton

    2015-01-01

    Background/Context:Federal policy, as codified in Race to the Top (RTT) funding guidelines, outlines four types of intervention: turnaround, restart, closure, and transformation. RTT has embraced a technocratic paradigm for school reform that frames choice less as the opportunity for the public to deliberate about what it wants from its schools…

  4. Chronically Low-Performing Schools and Turnaround: Evidence from Three States

    Science.gov (United States)

    Hansen, Michael; Choi, Kilchan

    2012-01-01

    The criteria for determining the student outcomes that define a school as having "turned around" are not well defined, and the definition of turnaround performance varies across studies. Although current policy initiatives offer guidelines for identifying CLP schools, there is no standard definition or methodology in common usage. This…

  5. Turnaround High School Principals: Recruit, Prepare and Empower Leaders of Change.

    Science.gov (United States)

    Schmidt-Davis, Jon; Bottoms, Gene

    2012-01-01

    Recent studies make one reality clear: While multiple factors can cause a low-performing high school to be in a turnaround situation, every high school that makes dramatic academic improvement has strong, effective school leadership. Turning a school around is no work for novices. It takes a skilled, visionary and proactive principal to pull apart…

  6. How to Know when Dramatic Change Is on Track: Leading Indicators of School Turnarounds

    Science.gov (United States)

    Kowal, Julie; Ableidinger, Joe

    2011-01-01

    In recent years, national policymakers have placed new emphasis on "school turnarounds" as a strategy for rapid, dramatic improvement in chronically failing schools, calling on education leaders to turn around performance in the 5,000 lowest-achieving schools nationwide. This goal may seem daunting, given the dismal success rates of…

  7. The Effects of School Turnaround in Tennessee's Achievement School District and Innovation Zones

    Science.gov (United States)

    Zimmer, Ron; Henry, Gary T.; Kho, Adam

    2017-01-01

    In recent years, the federal government has invested billions of dollars to reform chronically low-performing schools. To fulfill their federal Race to the Top grant agreement, Tennessee implemented three turnaround strategies that adhered to the federal restart and transformation models: (a) placed schools under the auspices of the Achievement…

  8. A Case Study of Change Strategies Implemented in a Turnaround Elementary School

    Science.gov (United States)

    Colson, Jo Ann

    2012-01-01

    This case study examined the change strategies in a turnaround school at the elementary level to understand and describe how change occurred and was sustained at this campus. This study examined the factors which contributed to the change in academic success of students, examined beliefs about change that led to the change process, identified the…

  9. Turnaround, Transformational, or Transactional Leadership: An Ethical Dilemma in School Reform

    Science.gov (United States)

    Mette, Ian M.; Scribner, Jay P.

    2014-01-01

    This case was written for school leaders, specifically building-level principals and central office administrators attempting to implement school turnaround reform efforts. Often, leaders who embark on this type of organizational change work in intense environments that produce high levels of pressure to demonstrate improvement in student…

  10. Tinkering and Turnarounds: Understanding the Contemporary Campaign to Improve Low-Performing Schools

    Science.gov (United States)

    Duke, Daniel L.

    2012-01-01

    An unprecedented amount of attention in recent years has been focused on turning around low-performing schools. Drawing on insights from Tyack and Cuban's (1995) "Tinkering Toward Utopia," the article analyzes the forces behind the school turnaround phenomenon and how they have evolved since passage of the No Child Left Behind Act. The…

  11. Investigating the Role of Human Resources in School Turnaround: Evidence from Two States

    Science.gov (United States)

    Hansen, Michael

    2012-01-01

    Teachers are generally recognized as the schooling factor accounting for the highest proportion of student learning outcomes (Aaronson et al., 2007; Hanushek, 1986). This implies the quick and dramatic improvement in school performance observed in turnaround (TA) schools was associated with a major change in the performance of its teachers. This…

  12. A general dead-time correction method based on live-time stamping. Application to the measurement of short-lived radionuclides.

    Science.gov (United States)

    Chauvenet, B; Bobin, C; Bouchard, J

    2017-12-01

    Dead-time correction formulae are established in the general case of superimposed non-homogeneous Poisson processes. Based on the same principles as conventional live-timed counting, this method exploits the additional information made available using digital signal processing systems, and especially the possibility to store the time stamps of live-time intervals. No approximation needs to be made to obtain those formulae. Estimates of the variances of corrected rates are also presented. This method is applied to the activity measurement of short-lived radionuclides. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Role of short-time acoustic temporal fine structure cues in sentence recognition for normal-hearing listeners.

    Science.gov (United States)

    Hou, Limin; Xu, Li

    2018-02-01

    Short-time processing was employed to manipulate the amplitude, bandwidth, and temporal fine structure (TFS) in sentences. Fifty-two native-English-speaking, normal-hearing listeners participated in four sentence-recognition experiments. Results showed that recovered envelope (E) played an important role in speech recognition when the bandwidth was > 1 equivalent rectangular bandwidth. Removing TFS drastically reduced sentence recognition. Preserving TFS greatly improved sentence recognition when amplitude information was available at a rate ≥ 10 Hz (i.e., time segment ≤ 100 ms). Therefore, the short-time TFS facilitates speech perception together with the recovered E and works with the coarse amplitude cues to provide useful information for speech recognition.

  14. Successful School Turnarounds: Seven Steps for District Leaders. Issue Brief

    Science.gov (United States)

    Kowal, Julie; Hassel, Emily Ayscue; Hassel, Bryan C.

    2009-01-01

    President Obama and Secretary Duncan have called upon states, districts, and education leaders to change the lives of millions of children by dramatically improving the nation's 5,000 lowest performing schools. These chronically failing schools will require intensive intervention to turn around performance that has fallen short of expectations for…

  15. A comparative analysis of short-range travel time prediction methods

    NARCIS (Netherlands)

    Huisken, Giovanni; van Berkum, Eric C.

    2003-01-01

    Increasing car mobility has lead to an increasing demand for traffic information. This contribution deals with information about travel times. When car drivers are provided with this type of information, the travel times should ideally be the times that they will encounter. As a result travel times

  16. Time-resolved neuroimaging of visual short term memory consolidation by post-perceptual attention shifts.

    Science.gov (United States)

    Hecht, Marcus; Thiemann, Ulf; Freitag, Christine M; Bender, Stephan

    2016-01-15

    Post-perceptual cues can enhance visual short term memory encoding even after the offset of the visual stimulus. However, both the mechanisms by which the sensory stimulus characteristics are buffered as well as the mechanisms by which post-perceptual selective attention enhances short term memory encoding remain unclear. We analyzed late post-perceptual event-related potentials (ERPs) in visual change detection tasks (100ms stimulus duration) by high-resolution ERP analysis to elucidate these mechanisms. The effects of early and late auditory post-cues (300ms or 850ms after visual stimulus onset) as well as the effects of a visual interference stimulus were examined in 27 healthy right-handed adults. Focusing attention with post-perceptual cues at both latencies significantly improved memory performance, i.e. sensory stimulus characteristics were available for up to 850ms after stimulus presentation. Passive watching of the visual stimuli without auditory cue presentation evoked a slow negative wave (N700) over occipito-temporal visual areas. N700 was strongly reduced by a visual interference stimulus which impeded memory maintenance. In contrast, contralateral delay activity (CDA) still developed in this condition after the application of auditory post-cues and was thereby dissociated from N700. CDA and N700 seem to represent two different processes involved in short term memory encoding. While N700 could reflect visual post processing by automatic attention attraction, CDA may reflect the top-down process of searching selectively for the required information through post-perceptual attention. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Clinical observation of one time short-pulse pattern scan laser pan-retinal photocoagulation for proliferative diabetic retinopathy

    Directory of Open Access Journals (Sweden)

    Xin Liu

    2016-04-01

    Full Text Available AIM: To investigate the clinical efficacy and benefit of short-pulse pattern scan laser(PASCALphotocoagulation for proliferative diabetic retinopathy(PDR.METHODS:Twenty-eight PDR patients(42 eyesunderwent short-pulse PASCAL pan-retinal photocoagulation(PRPwere analyzed.The best corrected visual acuity was ≥0.1 in 36 eyes, RESULTS: All the cases had no pain during the short-pulse PASCAL treatment.One year after treatments,the final visual acuity was improved in 6 eyes,kept stable in 28 eyes and decreased in 8 eyes; neovascularization were regressed in 18 eyes(43%, stable in 12 eyes(29%, uncontrolled in 12 eyes(29%. Five eyes(12%received vitrectomy due to vitreous hemorrhage.Compared with before operation, retina thickness in central fovea of macula and visual field had no obvious change after one-time PASCAL PRP(P>0.05. CONCLUSION:The one-time short-pulse PASCAL PRP could stabilize the progress of PDR safely, effectively and simply.

  18. Increasing Short-Stay Unplanned Hospital Admissions among Children in England; Time Trends Analysis ’97–‘06

    Science.gov (United States)

    Saxena, Sonia; Bottle, Alex; Gilbert, Ruth; Sharland, Mike

    2009-01-01

    Background Timely care by general practitioners in the community keeps children out of hospital and provides better continuity of care. Yet in the UK, access to primary care has diminished since 2004 when changes in general practitioners' contracts enabled them to ‘opt out’ of providing out-of-hours care and since then unplanned pediatric hospital admission rates have escalated, particularly through emergency departments. We hypothesised that any increase in isolated short stay admissions for childhood illness might reflect failure to manage these cases in the community over a 10 year period spanning these changes. Methods and Findings We conducted a population based time trends study of major causes of hospital admission in children 2 days. By 2006, 67.3% of all unplanned admissions were isolated short stays <2 days. The increases in admission rates were greater for common non-infectious than infectious causes of admissions. Conclusions Short stay unplanned hospital admission rates in young children in England have increased substantially in recent years and are not accounted for by reductions in length of in-hospital stay. The majority are isolated short stay admissions for minor illness episodes that could be better managed by primary care in the community and may be evidence of a failure of primary care services. PMID:19829695

  19. Time-dependent screening of a positive charge distribution in metals: Excitons on an ultra-short time scale

    OpenAIRE

    Schöne, Wolf-Dieter; Ekardt, Walter

    2000-01-01

    Experiments determining the lifetime of excited electrons in crystalline copper reveal states which cannot be interpreted as Bloch states [S. Ogawa {\\it et al.}, Phys. Rev. B {\\bf 55}, 10869 (1997)]. In this article we propose a model which explains these states as transient excitonic states in metals. The physical background of transient excitons is the finite time a system needs to react to an external perturbation, in other words, the time which is needed to build up a polarization cloud. ...

  20. Efficient Computation of Multiscale Entropy over Short Biomedical Time Series Based on Linear State-Space Models

    Directory of Open Access Journals (Sweden)

    Luca Faes

    2017-01-01

    Full Text Available The most common approach to assess the dynamical complexity of a time series across multiple temporal scales makes use of the multiscale entropy (MSE and refined MSE (RMSE measures. In spite of their popularity, MSE and RMSE lack an analytical framework allowing their calculation for known dynamic processes and cannot be reliably computed over short time series. To overcome these limitations, we propose a method to assess RMSE for autoregressive (AR stochastic processes. The method makes use of linear state-space (SS models to provide the multiscale parametric representation of an AR process observed at different time scales and exploits the SS parameters to quantify analytically the complexity of the process. The resulting linear MSE (LMSE measure is first tested in simulations, both theoretically to relate the multiscale complexity of AR processes to their dynamical properties and over short process realizations to assess its computational reliability in comparison with RMSE. Then, it is applied to the time series of heart period, arterial pressure, and respiration measured for healthy subjects monitored in resting conditions and during physiological stress. This application to short-term cardiovascular variability documents that LMSE can describe better than RMSE the activity of physiological mechanisms producing biological oscillations at different temporal scales.

  1. Short-time dynamics of lysozyme solutions with competing short-range attraction and long-range repulsion: Experiment and theory

    Science.gov (United States)

    Riest, Jonas; Nägele, Gerhard; Liu, Yun; Wagner, Norman J.; Godfrin, P. Douglas

    2018-02-01

    Recently, atypical static features of microstructural ordering in low-salinity lysozyme protein solutions have been extensively explored experimentally and explained theoretically based on a short-range attractive plus long-range repulsive (SALR) interaction potential. However, the protein dynamics and the relationship to the atypical SALR structure remain to be demonstrated. Here, the applicability of semi-analytic theoretical methods predicting diffusion properties and viscosity in isotropic particle suspensions to low-salinity lysozyme protein solutions is tested. Using the interaction potential parameters previously obtained from static structure factor measurements, our results of Monte Carlo simulations representing seven experimental lysoyzme samples indicate that they exist either in dispersed fluid or random percolated states. The self-consistent Zerah-Hansen scheme is used to describe the static structure factor, S(q), which is the input to our calculation schemes for the short-time hydrodynamic function, H(q), and the zero-frequency viscosity η. The schemes account for hydrodynamic interactions included on an approximate level. Theoretical predictions for H(q) as a function of the wavenumber q quantitatively agree with experimental results at small protein concentrations obtained using neutron spin echo measurements. At higher concentrations, qualitative agreement is preserved although the calculated hydrodynamic functions are overestimated. We attribute the differences for higher concentrations and lower temperatures to translational-rotational diffusion coupling induced by the shape and interaction anisotropy of particles and clusters, patchiness of the lysozyme particle surfaces, and the intra-cluster dynamics, features not included in our simple globular particle model. The theoretical results for the solution viscosity, η, are in qualitative agreement with our experimental data even at higher concentrations. We demonstrate that semi

  2. Influence of characteristics of time series on short-term forecasting error parameter changes in real time

    Science.gov (United States)

    Klevtsov, S. I.

    2018-05-01

    The impact of physical factors, such as temperature and others, leads to a change in the parameters of the technical object. Monitoring the change of parameters is necessary to prevent a dangerous situation. The control is carried out in real time. To predict the change in the parameter, a time series is used in this paper. Forecasting allows one to determine the possibility of a dangerous change in a parameter before the moment when this change occurs. The control system in this case has more time to prevent a dangerous situation. A simple time series was chosen. In this case, the algorithm is simple. The algorithm is executed in the microprocessor module in the background. The efficiency of using the time series is affected by its characteristics, which must be adjusted. In the work, the influence of these characteristics on the error of prediction of the controlled parameter was studied. This takes into account the behavior of the parameter. The values of the forecast lag are determined. The results of the research, in the case of their use, will improve the efficiency of monitoring the technical object during its operation.

  3. Time-resolved measurement of the quantum states of photons using two-photon interference with short-time reference pulses

    International Nuclear Information System (INIS)

    Ren Changliang; Hofmann, Holger F.

    2011-01-01

    To fully utilize the energy-time degree of freedom of photons for optical quantum-information processes, it is necessary to control and characterize the temporal quantum states of the photons at extremely short time scales. For measurements of the temporal coherence of the quantum states beyond the time resolution of available detectors, two-photon interference with a photon in a short-time reference pulse may be a viable alternative. In this paper, we derive the temporal measurement operators for the bunching statistics of a single-photon input state with a photon from a weak coherent reference pulse. It is shown that the effects of the pulse shape of the reference pulse can be expressed in terms of a spectral filter selecting the bandwidth within which the measurement can be treated as an ideal projection on eigenstates of time. For full quantum tomography, temporal coherence can be determined by using superpositions of reference pulses at two different times. Moreover, energy-time entanglement can be evaluated based on the two-by-two entanglement observed in the coherences between pairs of detection times.

  4. Characterization of new eye drops with choline salicylate and assessment of their irritancy by in vitro short time exposure tests.

    Science.gov (United States)

    Wroblewska, Katarzyna; Kucinska, Małgorzata; Murias, Marek; Lulek, Janina

    2015-09-01

    The aim of our study was to examine the irritation potential of new eye drops containing 2% choline salicylate (CS) as an active pharmaceutical ingredient (API) and various polymers increasing eye drop viscosity (hydroxyethylcellulose, hydroxypropyl methylcellulose, methylcellulose, polyvinyl alcohol, polyvinylpyrrolidone). The standard method for assessing the potential of irritating substances has been the Draize rabbit eye test. However the European Centre for Validation of Alternative Methods and the Coordinating Committee for Validation of Alternative Methods recommend, short time exposure (STE) in vitro tests as an alternative method for assessing eye irritation. The eye irritation potential was determined using cytotoxicity test methods for rabbit corneal cell line (SIRC) after 5 min exposure. The viability of cells was determined using two cytotoxicity assays: MTT and Neutral Red Uptake. According to the irritation rankings for the short time exposure test, all tested eye drops are classified as non-irritating (cell viability >70%).

  5. High-Temperature Short-Time Pasteurization System for Donor Milk in a Human Milk Bank Setting

    OpenAIRE

    Diana Escuder-Vieco; Irene Espinosa-Martos; Juan M. Rodríguez; Nieves Corzo; Antonia Montilla; Pablo Siegfried; Carmen R. Pallás-Alonso; Carmen R. Pallás-Alonso; Leónides Fernández

    2018-01-01

    Donor milk is the best alternative for the feeding of preterm newborns when mother's own milk is unavailable. For safety reasons, it is usually pasteurized by the Holder method (62.5°C for 30 min). Holder pasteurization results in a microbiological safe product but impairs the activity of many biologically active compounds such as immunoglobulins, enzymes, cytokines, growth factors, hormones or oxidative stress markers. High-temperature short-time (HTST) pasteurization has been proposed as an...

  6. Testing of Commercial Milk Production Technology Using A Combination of High Temperature Short Time and Pulsed Electric Field

    OpenAIRE

    Hadi A; Widjanarko SB; Kusnadi J

    2016-01-01

    The development of milk processing technology has grown excessively, and it contains advantage and disadvantage. This study used mixed between PEF (Pulsed Electric Field) and High Temperature Short Time (HTST) to produce milk processed product which is effective and efficient in killing milk microorganism without changing its color, scent, and nutrient content of processed product, therefore producing commercial sterile milk product in accord with milk Indonesian National Standard (SNI). The ...

  7. Experience from the transportation of irradiated WWER-440 fuel assemblies at the Kozloduy NPP site after a short cooling time

    International Nuclear Information System (INIS)

    Stoyanova, I.; Kamenov, A.; Byrzev, L.; Christoskov, I.

    2003-01-01

    Results from the analysis and experimental verification of the radiation and shielding characteristics of non-standard loading patterns of the VSPOT transport cask used for transportation of irradiated fuel assemblies after a short cooling time (120 180 days) on the site of the Kozloduy NPP are presented. An additional safety criterion related to the introduced modifications to the standard procedure of using the transport cask is formulated and discussed (Authors)

  8. On the applicability of short time measurements to the determination of annual average of radon concentration in dwelling

    International Nuclear Information System (INIS)

    Loskiewicz, J.; Olko, P.; Swakon, J.; Bogacz, J.; Janik, M.; Mazur, D.; Mazur, J.

    1998-01-01

    The variation of radon concentration in some houses in the Krakow region was investigated in order to compare results obtained using various measuring techniques. It is concluded that short-term measurements should last at least 4 days to avoid errors exceeding 30%; that weather parameters and human activity during the measurement should be recorded; that measurements should be repeated several times under various weather conditions; that seasonal variation in the region should be taken into account. (A.K.)

  9. Use of cadmium sulphide to measure integrated dose in short-time irradiation

    International Nuclear Information System (INIS)

    Nimnual, S.

    1975-01-01

    An experiment was made to measure the dose from a short burst of X-rays in the order of 1 second or less by means of the cadmium sulphide photoconductive cell. If protected from light, the CdS cell has a very high resistance such that it does not discharge a capacitor appreciably. But during irradiation, the resistance decreases temporarily and an amount of charge will leak from the capacitor through the Ca S cell. The result to this experiment shows that the principle works very well but it is necessary to add another fixed high resistance of about 10 7 ohms into the circuit in order to get results independent of the dose-rate. The equipment used in this experiment can measure a dose as low as 6 m R

  10. High-Temperature-Short-Time Annealing Process for High-Performance Large-Area Perovskite Solar Cells.

    Science.gov (United States)

    Kim, Minjin; Kim, Gi-Hwan; Oh, Kyoung Suk; Jo, Yimhyun; Yoon, Hyun; Kim, Ka-Hyun; Lee, Heon; Kim, Jin Young; Kim, Dong Suk

    2017-06-27

    Organic-inorganic hybrid metal halide perovskite solar cells (PSCs) are attracting tremendous research interest due to their high solar-to-electric power conversion efficiency with a high possibility of cost-effective fabrication and certified power conversion efficiency now exceeding 22%. Although many effective methods for their application have been developed over the past decade, their practical transition to large-size devices has been restricted by difficulties in achieving high performance. Here we report on the development of a simple and cost-effective production method with high-temperature and short-time annealing processing to obtain uniform, smooth, and large-size grain domains of perovskite films over large areas. With high-temperature short-time annealing at 400 °C for 4 s, the perovskite film with an average domain size of 1 μm was obtained, which resulted in fast solvent evaporation. Solar cells fabricated using this processing technique had a maximum power conversion efficiency exceeding 20% over a 0.1 cm 2 active area and 18% over a 1 cm 2 active area. We believe our approach will enable the realization of highly efficient large-area PCSs for practical development with a very simple and short-time procedure. This simple method should lead the field toward the fabrication of uniform large-scale perovskite films, which are necessary for the production of high-efficiency solar cells that may also be applicable to several other material systems for more widespread practical deployment.

  11. Nonlinear detection of disordered voice productions from short time series based on a Volterra-Wiener-Korenberg model

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Yu, E-mail: yuzhang@xmu.edu.cn [Key Laboratory of Underwater Acoustic Communication and Marine Information Technology of the Ministry of Education, Xiamen University, Xiamen Fujian 361005 (China); Sprecher, Alicia J. [Department of Surgery, Division of Otolaryngology - Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-7375 (United States); Zhao Zongxi [Key Laboratory of Underwater Acoustic Communication and Marine Information Technology of the Ministry of Education, Xiamen University, Xiamen Fujian 361005 (China); Jiang, Jack J. [Department of Surgery, Division of Otolaryngology - Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-7375 (United States)

    2011-09-15

    Highlights: > The VWK method effectively detects the nonlinearity of a discrete map. > The method describes the chaotic time series of a biomechanical vocal fold model. > Nonlinearity in laryngeal pathology is detected from short and noisy time series. - Abstract: In this paper, we apply the Volterra-Wiener-Korenberg (VWK) model method to detect nonlinearity in disordered voice productions. The VWK method effectively describes the nonlinearity of a third-order nonlinear map. It allows for the analysis of short and noisy data sets. The extracted VWK model parameters show an agreement with the original nonlinear map parameters. Furthermore, the VWK mode method is applied to successfully assess the nonlinearity of a biomechanical voice production model simulating irregular vibratory dynamics of vocal folds with a unilateral vocal polyp. Finally, we show the clinical applicability of this nonlinear detection method to analyze the electroglottographic data generated by 14 patients with vocal nodules or polyps. The VWK model method shows potential in describing the nonlinearity inherent in disordered voice productions from short and noisy time series that are common in the clinical setting.

  12. Nonlinear detection of disordered voice productions from short time series based on a Volterra-Wiener-Korenberg model

    International Nuclear Information System (INIS)

    Zhang Yu; Sprecher, Alicia J.; Zhao Zongxi; Jiang, Jack J.

    2011-01-01

    Highlights: → The VWK method effectively detects the nonlinearity of a discrete map. → The method describes the chaotic time series of a biomechanical vocal fold model. → Nonlinearity in laryngeal pathology is detected from short and noisy time series. - Abstract: In this paper, we apply the Volterra-Wiener-Korenberg (VWK) model method to detect nonlinearity in disordered voice productions. The VWK method effectively describes the nonlinearity of a third-order nonlinear map. It allows for the analysis of short and noisy data sets. The extracted VWK model parameters show an agreement with the original nonlinear map parameters. Furthermore, the VWK mode method is applied to successfully assess the nonlinearity of a biomechanical voice production model simulating irregular vibratory dynamics of vocal folds with a unilateral vocal polyp. Finally, we show the clinical applicability of this nonlinear detection method to analyze the electroglottographic data generated by 14 patients with vocal nodules or polyps. The VWK model method shows potential in describing the nonlinearity inherent in disordered voice productions from short and noisy time series that are common in the clinical setting.

  13. Effects of light guide and magnetic field on the characteristics of the short time measuring system

    International Nuclear Information System (INIS)

    Yamada, Yoshihiro; Ohira, Kyozo

    1977-01-01

    In order to construct the nuclear life-time measurement apparatus with good energy and time resolution, consisting of DuMond type beta-ray spectrometer and plastic scintillator, experimental studies are carried out for the effects of light guide and magnetic field on the time resolution, and for the effects of μ-metal shielding on the energy resolution. It has been found that all these effects could be practically diminished. (auth.)

  14. Short-Term Bus Passenger Demand Prediction Based on Time Series Model and Interactive Multiple Model Approach

    Directory of Open Access Journals (Sweden)

    Rui Xue

    2015-01-01

    Full Text Available Although bus passenger demand prediction has attracted increased attention during recent years, limited research has been conducted in the context of short-term passenger demand forecasting. This paper proposes an interactive multiple model (IMM filter algorithm-based model to predict short-term passenger demand. After aggregated in 15 min interval, passenger demand data collected from a busy bus route over four months were used to generate time series. Considering that passenger demand exhibits various characteristics in different time scales, three time series were developed, named weekly, daily, and 15 min time series. After the correlation, periodicity, and stationarity analyses, time series models were constructed. Particularly, the heteroscedasticity of time series was explored to achieve better prediction performance. Finally, IMM filter algorithm was applied to combine individual forecasting models with dynamically predicted passenger demand for next interval. Different error indices were adopted for the analyses of individual and hybrid models. The performance comparison indicates that hybrid model forecasts are superior to individual ones in accuracy. Findings of this study are of theoretical and practical significance in bus scheduling.

  15. Time does not cause forgetting in short-term serial recall.

    Science.gov (United States)

    Lewandowsky, Stephan; Duncan, Matthew; Brown, Gordon D A

    2004-10-01

    Time-based theories expect memory performance to decline as the delay between study and recall of an item increases. The assumption of time-based forgetting, central to many models of serial recall, underpins their key behaviors. Here we compare the predictions of time-based and event-based models by simulation and test them in two experiments using a novel manipulation of the delay between study and retrieval. Participants were trained, via corrective feedback, to recall at different speeds, thus varying total recall time from 6 to 10 sec. In the first experiment, participants used the keyboard to enter their responses but had to repeat a word (called the suppressor) aloud during recall to prevent rehearsal. In the second experiment, articulation was again required, but recall was verbal and was paced by the number of repetitions of the suppressor in between retrieval of items. In both experiments, serial position curves for all retrieval speeds overlapped, and output time had little or no effect. Comparative evaluation of a time-based and an event-based model confirmed that these results present a particular challenge to time-based approaches. We conclude that output interference, rather than output time, is critical in serial recall.

  16. Estimation of train dwell time at short stops based on track occupation event data

    NARCIS (Netherlands)

    Li, D.; Daamen, W.; Goverde, R.M.P.

    2015-01-01

    Train dwell time is one of the most unpredictable components of railway operations mainly due to the varying volumes of alighting and boarding passengers. For reliable estimations of train running times and route conflicts on main lines it is however necessary to obtain accurate estimations of dwell

  17. FALSE DETERMINATIONS OF CHAOS IN SHORT NOISY TIME SERIES. (R828745)

    Science.gov (United States)

    A method (NEMG) proposed in 1992 for diagnosing chaos in noisy time series with 50 or fewer observations entails fitting the time series with an empirical function which predicts an observation in the series from previous observations, and then estimating the rate of divergenc...

  18. Development of a New Class of Scintillating Fibres with Very Short Decay Time and High Light Yield

    International Nuclear Information System (INIS)

    Borshchev, O.; Ponomarenko, S.; Surin, N.; Cavalcante, A.B.R.; Gavardi, L.; Gruber, L.; Joram, C.; Shinji, O.

    2017-01-01

    We present first studies of a new class of scintillating fibres which are characterised by very short decay times and high light yield. The fibres are based on a novel type of luminophores admixed to a polystyrene core matrix. These so-called Nanostructured Organosilicon Luminophores (NOL) have high photoluminescense quantum yield and decay times just above 1 ns. A blue and a green emitting prototype fibre with 250 μm diameter were produced and characterised in terms of attenuation length, ionisation light yield, decay time and tolerance to x-ray irradiation. The well-established Kuraray SCSF-78 and SCSF-3HF fibres were taken as references. Even though the two prototype fibres mark just an intermediate step in an ongoing development, their performance is already on a competitive level. In particular, their decay time constants are about a factor of two shorter than the fastest known fibres, which makes them promising candidates for time critical applications.

  19. VCSELs in short-pulse operation for time-of-flight applications

    Science.gov (United States)

    Moench, Holger; Gronenborn, Stephan; Gu, Xi; Gudde, Ralph; Herper, Markus; Kolb, Johanna; Miller, Michael; Smeets, Michael; Weigl, Alexander

    2018-02-01

    VCSEL arrays are the ideal light source for 3D imaging applications. The narrow emission spectrum and the ability for short pulses make them superior to LEDs. Combined with fast photodiodes or special camera chips spatial information can be obtained which is needed in diverse applications like camera autofocus, indoor navigation, 3D-object recognition, augmented reality or autonomously driving vehicles. Pulse operation at the ns scale and at low duty cycle can work with significantly higher current than traditionally used for VCSELs in continuous wave operation. With reduced thermal limitations at low average heat dissipation very high currents become feasible and tens of Watts output power have been realized with small VCSEL chips. The optical emission pattern of VCSELs can be tailored to the desired field of view using beam shaping elements. Such optical elements also enable laser safe class 1 products. A detailed analysis of the complete system and the operation mode is required to calculate the maximum permitted power for a safe system. The good VCSEL properties like robustness, stability over temperature and the potential for integrated solutions open a huge potential for VCSELs in new mass applications in the consumer and automotive markets.

  20. Short- and long-term effects of real-time medication monitoring with short message service (SMS) reminders for missed doses on the refill adherence of people with Type 2 diabetes: evidence from a randomised controlled trial.

    NARCIS (Netherlands)

    Vervloet, M.; Dijk, L. van; Bakker, D.H. de; Souverein, P.C.; Santen-Reestman, J.; Vlijmen, B. van; Aarle, M.C.W. van; Hoek, L.S. van der; Bouvy, M.L.

    2014-01-01

    Aims: To investigate short- and long-term effects of real-time monitoring medication use combined with short message service (SMS) reminders for missed doses on refill adherence to oral anti-diabetic medication. Methods: A randomized controlled trial with two intervention groups and one control

  1. Incorporating geostrophic wind information for improved space–time short-term wind speed forecasting

    KAUST Repository

    Zhu, Xinxin; Bowman, Kenneth P.; Genton, Marc G.

    2014-01-01

    pressure, temperature, and other meteorological variables, no improvement in forecasting accuracy was found by incorporating air pressure and temperature directly into an advanced space-time statistical forecasting model, the trigonometric direction diurnal

  2. The impact of short prehospital times on trauma center performance benchmarking: An ecologic study.

    Science.gov (United States)

    Byrne, James P; Mann, N Clay; Hoeft, Christopher J; Buick, Jason; Karanicolas, Paul; Rizoli, Sandro; Hunt, John P; Nathens, Avery B

    2016-04-01

    Emergency medical service (EMS) prehospital times vary between regions, yet the impact of local prehospital times on trauma center (TC) performance is unknown. To inform external benchmarking efforts, we explored the impact of EMS prehospital times on the risk-adjusted rate of emergency department (ED) death and overall hospital mortality at urban TCs across the United States. We used a novel ecologic study design, linking EMS data from the National EMS Information System to TCs participating in the American College of Surgeons' Trauma Quality Improvement Program (TQIP) by destination zip code. This approach provided EMS times for populations of injured patients transported to TQIP centers. We defined the exposure of interest as the 90th percentile total prehospital time (PHT) for each TC. TCs were then stratified by PHT quartile. Analyses were limited to adult patients with severe blunt or penetrating trauma, transported directly by land to urban TQIP centers. Random-intercept multilevel modeling was used to evaluate the risk-adjusted relationship between PHT quartile and the outcomes of ED death and overall hospital mortality. During the study period, 119,740 patients met inclusion criteria at 113 TCs. ED death occurred in 1% of patients, and overall mortality was 7.2%. Across all centers, the median PHT was 61 minutes (interquartile range, 53-71 minutes). After risk adjustment, TCs in regions with the shortest quartile of PHTs (<53 minutes) had significantly greater odds of ED death compared with those with the longest PHTs (odds ratio, 2.00; 95% confidence interval, 1.43-2.78). However, there was no association between PHT and overall TC mortality. At urban TCs, local EMS prehospital times are a significant predictor of ED death. However, no relationship exists between prehospital time and overall TC risk-adjusted mortality. Therefore, there is no evidence for the inclusion of EMS prehospital time in external benchmarking analyses.

  3. Short-Term Wave Forecasting for Real-Time Control of Wave Energy Converters

    OpenAIRE

    Fusco, Francesco; Ringwood, John

    2010-01-01

    Real-time control of wave energy converters requires knowledge of future incident wave elevation in order to approach optimal efficiency of wave energy extraction. We present an approach where the wave elevation is treated as a time series and it is predicted only from its past history. A comparison of a range of forecasting methodologies on real wave observations from two different locations shows how the relatively simple linear autoregressive model, which implicitly models the cyclical beh...

  4. RubiShort: Reducing scan time in 82Rb heart scans to minimize movements artifacts

    DEFF Research Database (Denmark)

    Madsen, Jeppe; Vraa, Kaspar J.; Harms, Hans

    .013x, R2=0.98; %Reversible: y=1.008x, R2=0.95; TPD: y=1.000x, R2=0.99). Conclusion:, Scan time of myocardial perfusion scans using 82Rb can be reduced from 7 min. to 5 min. without loss of quantitative accuracy. Since patient motion is frequent in the last minutes of the scans, scan time reduction...

  5. Dead-time corrections on long-interval measurements of short-lived activities

    International Nuclear Information System (INIS)

    Irfan, M.

    1977-01-01

    A method has been proposed to make correction for counting losses due to dead time where the counting interval is comparable to or larger than the half-life of the activity under investigation. Counts due to background and any long-lived activity present in the source have been taken into consideration. The method is, under certain circumstances, capable of providing a valuable check on the accuracy of the dead time of the counting system. (Auth.)

  6. Association between prehospital time interval and short-term outcome in acute heart failure patients.

    Science.gov (United States)

    Takahashi, Masashi; Kohsaka, Shun; Miyata, Hiroaki; Yoshikawa, Tsutomu; Takagi, Atsutoshi; Harada, Kazumasa; Miyamoto, Takamichi; Sakai, Tetsuo; Nagao, Ken; Sato, Naoki; Takayama, Morimasa

    2011-09-01

    Acute heart failure (AHF) is one of the most frequently encountered cardiovascular conditions that can seriously affect the patient's prognosis. However, the importance of early triage and treatment initiation in the setting of AHF has not been recognized. The Tokyo Cardiac Care Unit Network Database prospectively collected information of emergency admissions to acute cardiac care facilities in 2005-2007 from 67 participating hospitals in the Tokyo metropolitan area. We analyzed records of 1,218 AHF patients transported to medical centers via emergency medical services (EMS). AHF was defined as rapid onset or change in the signs and symptoms of heart failure, resulting in the need for urgent therapy. Patients with acute coronary syndrome were excluded from this analysis. Logistic regression analysis was performed to calculate the risk-adjusted in-hospital mortality. A majority of the patients were elderly (76.1 ± 11.5 years old) and male (54.1%). The overall in-hospital mortality rate was 6.0%. The median time interval between symptom onset and EMS arrival (response time) was 64 minutes (interquartile range [IQR] 26-205 minutes), and that between EMS arrival and ER arrival (transportation time) was 27 minutes (IQR 9-78 minutes). The risk-adjusted mortality increased with transportation time, but did not correlate with the response time. Those who took >45 minutes to arrive at the medical centers were at a higher risk for in-hospital mortality (odds ratio 2.24, 95% confidence interval 1.17-4.31; P = .015). Transportation time correlated with risk-adjusted mortality, and steps should be taken to reduce the EMS transfer time to improve the outcome in AHF patients. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. Geometric patterns of time-delay plots from different cardiac rhythms and arrhythmias using short-term EKG signals.

    Science.gov (United States)

    Borracci, Raúl A; Montoya Pulvet, José D; Ingino, Carlos A; Fitz Maurice, Mario; Hirschon Prado, Alfredo; Dominé, Enrique

    2017-12-27

    To date, no systematic work has been intended to describe spatio-temporal patterns of cardiac rhythms using only short series of RR intervals, to facilitate visual or computerized-aided identification of EKG motifs for use in clinical practice. The aim of this study was to detect and classify eye-catching geometric patterns of Poincaré time-delay plots from different types of cardiac rhythms and arrhythmias using short-term EKG signals. Approximately 150-300 representative, consecutive beats were retrieved from 24-h Holter registers of 100 patients with different heart rhythms. Two-dimensional Poincaré charts were created, and the resulting geometric patterns were transformed into representative familiar eye-catching drawings to interpret different arrhythmias. Poincaré plot representation of RR interval data revealed a wide variety of visual patterns: (i) comet-shaped for sinus rhythm; (ii) torpedo-shaped for sinus bradycardia; (iii) cigarette-shaped for sinus tachycardia; (iv) butterfly-shaped for sinus tachycardia and isolated atrial premature complexes; (v) arrow-shaped for isolated premature complexes and inappropriate sinus tachycardia; (vi) inverted fan-shaped for sinus rhythm with frequent atrial premature complexes; (vii) tornado-shaped for atrial flutter and atrial tachycardia; and (viii) fan-shaped for atrial fibrillation. Modified Poincaré plots with smoothed lines connecting successive points could accurately classify different types of arrhythmias based on short RR interval sequence variability. Characteristic emergent patterns can be visually identified and eventually could be distinguished by an automatic classification system able to discern between arrhythmias. This work provides an alternative method to interpret time-delay plots obtained from short-term EKG signal recordings. © 2017 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  8. Femtosecond timing-jitter between photo-cathode laser and ultra-short electron bunches by means of hybrid compression

    CERN Document Server

    Pompili, Riccardo; Bellaveglia, M; Biagioni, A; Castorina, G; Chiadroni, E; Cianchi, A; Croia, M; Di Giovenale, D; Ferrario, M; Filippi, F; Gallo, A; Gatti, G; Giorgianni, F; Giribono, A; Li, W; Lupi, S; Mostacci, A; Petrarca, M; Piersanti, L; Di Pirro, G; Romeo, S; Scifo, J; Shpakov, V; Vaccarezza, C; Villa, F

    2017-01-01

    The generation of ultra-short electron bunches with ultra-low timing-jitter relative to the photo-cathode (PC) laser has been experimentally proved for the first time at the SPARC_LAB test-facility (INFN-LNF, Frascati) exploiting a two-stage hybrid compression scheme. The first stage employs RF-based compression (velocity-bunching), which shortens the bunch and imprints an energy chirp on it. The second stage is performed in a non-isochronous dogleg line, where the compression is completed resulting in a final bunch duration below 90 fs (rms). At the same time, the beam arrival timing-jitter with respect to the PC laser has been measured to be lower than 20 fs (rms). The reported results have been validated with numerical simulations.

  9. Femtosecond timing-jitter between photo-cathode laser and ultra-short electron bunches by means of hybrid compression

    International Nuclear Information System (INIS)

    Pompili, R; Anania, M P; Bellaveglia, M; Biagioni, A; Castorina, G; Chiadroni, E; Croia, M; Giovenale, D Di; Ferrario, M; Gallo, A; Gatti, G; Cianchi, A; Filippi, F; Giorgianni, F; Giribono, A; Lupi, S; Mostacci, A; Petrarca, M; Piersanti, L; Li, W

    2016-01-01

    The generation of ultra-short electron bunches with ultra-low timing-jitter relative to the photo-cathode (PC) laser has been experimentally proved for the first time at the SPARC-LAB test-facility (INFN-LNF, Frascati) exploiting a two-stage hybrid compression scheme. The first stage employs RF-based compression (velocity-bunching), which shortens the bunch and imprints an energy chirp on it. The second stage is performed in a non-isochronous dogleg line, where the compression is completed resulting in a final bunch duration below 90 fs (rms). At the same time, the beam arrival timing-jitter with respect to the PC laser has been measured to be lower than 20 fs (rms). The reported results have been validated with numerical simulations. (paper)

  10. Markov Chain Modelling for Short-Term NDVI Time Series Forecasting

    Directory of Open Access Journals (Sweden)

    Stepčenko Artūrs

    2016-12-01

    Full Text Available In this paper, the NDVI time series forecasting model has been developed based on the use of discrete time, continuous state Markov chain of suitable order. The normalised difference vegetation index (NDVI is an indicator that describes the amount of chlorophyll (the green mass and shows the relative density and health of vegetation; therefore, it is an important variable for vegetation forecasting. A Markov chain is a stochastic process that consists of a state space. This stochastic process undergoes transitions from one state to another in the state space with some probabilities. A Markov chain forecast model is flexible in accommodating various forecast assumptions and structures. The present paper discusses the considerations and techniques in building a Markov chain forecast model at each step. Continuous state Markov chain model is analytically described. Finally, the application of the proposed Markov chain model is illustrated with reference to a set of NDVI time series data.

  11. Efficacy and cytotoxicity of a bleaching gel after short application times on dental enamel.

    Science.gov (United States)

    Soares, Diana Gabriela; Ribeiro, Ana Paula Dias; da Silveira Vargas, Fernanda; Hebling, Josimeri; de Souza Costa, Carlos Alberto

    2013-11-01

    This study aimed to evaluate and correlate the efficacy and cytotoxicity of a 35 % hydrogen peroxide (HP) bleaching gel after different application times on dental enamel. Enamel/dentin disks in artificial pulp chambers were placed in wells containing culture medium. The following groups were formed: G1, control (no bleaching); G2 and G3, three or one 15-min bleaching applications, respectively; and G4 and G5, three or one 5-min bleaching applications, respectively. Extracts (culture medium with bleaching gel components) were applied for 60 min on cultured odontoblast-like MDPC-23 cells. Cell metabolism (methyl tetrazolium assay) (Kruskal-Wallis/Mann-Whitney; α = 5 %) and cell morphology (scanning electron microscopy) were analyzed immediately after the bleaching procedures and the trans-enamel and trans-dentinal HP diffusion quantified (one-way analysis of variance/Tukey's test; α = 5 %). The alkaline phosphatase (ALP) activity was evaluated 24 h after the contact time of the extracts with the cells (Kruskal-Wallis/Mann-Whitney; α = 5 %). Tooth color was analyzed before and 24 h after bleaching using a spectrophotometer according to the Commission Internationale de l'Eclairage L*a*b* system (Kruskal-Wallis/Mann-Whitney; α = 0.05). Significant difference (p 0.05). The lowest amount of HP diffusion was observed in G5 (p 0.05). HP diffusion through dental tissues and its cytotoxic effects were proportional to the contact time of the bleaching gel with enamel. However, shorter bleaching times reduced bleaching efficacy. Shortening the in-office tooth bleaching time could be an alternative to minimize the cytotoxic effects of this clinical procedure to pulp tissue. However, the reduced time of bleaching agent application on enamel may not provide adequate esthetic outcome.

  12. An evaluation of the optimum timing for planting short rotation coppice

    Energy Technology Data Exchange (ETDEWEB)

    Turnbull, D.J.; Jefferies, R.; Parfitt, R.

    2004-07-01

    This report summarises the results of a project to determine the optimum timing for planting, evaluate problems due to late planting in the spring, and to study the planting of willows at different times during the autumn. Details are given of the site installation, previous research on the effect of planting date and storage, and assessment of the establishment and biomass productivity and the viability of cuttings in long-term storage. Charts illustrating biomass productivity are presented, and long-term storage of willow cuttings for autumn planting is discussed.

  13. Economic incentives of short out-of-reactor time for fast breeder reactor fuel

    International Nuclear Information System (INIS)

    Bentley, B.W.; Haffner, D.R.

    1975-01-01

    Economic benefits (primarily reduced uranium ore and enrichment expenditures) can be realized by reducing the LMFBR out-of-reactor fuel cycle time only if process cost penalties and R and D costs can be minimized. The results of the evaluation presented show the potential gross benefits of reducing the out-of-reactor time and the effects of various associated cost penalties on these benefits. The gross benefit results estimate the potential savings in electrical power generation in the next 50 years using constant 1975 dollars and discounting the costs at 7 1 / 2 percent per year

  14. Energy policy turnaround and agriculture. Proceedings; Energiewende und Landwirtschaft. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Wendl, Georg (ed.)

    2012-11-15

    Within the land-technical annual meeting at 22nd November, 2012 in the training centre of the Banz monastery (Bad Staffelstein, Federal Republic of Germany), the following lectures were held: (1) Opportunities and potentials of renewable energies in Bavaria (Rupert Schaefer); (2) Consumption of electricity and energy efficiency in agricultural operation (Stefan Neser); (3) Short-rotation plantations - Processes, efficiency and ecologic balance (Frank Burger); (4) Bavarian pilot plants for the production of biogas - Results from five years of monitoring (Mathias Effenberger); (5) Farm biomass conversion plants up to 75 kW - Opportunities and limits (Andreas Weber); (6) Photovoltaic power plants and wind power plants in the Bavarian agriculture - Where is it all going? (Johannes Graf); (7) Wind energy - Regional value creation by an area model and citizen's participation using an example in Creussen (district Bayreuth) (Harald Mild); (8) Regional power connecting using Hollfeld as an example (Markus Pirkelmann).

  15. Time-resolved plasma spectroscopy of thin foils heated by a relativistic-intensity short-pulse laser

    International Nuclear Information System (INIS)

    Audebert, P.; Gauthier, J.-C.; Shepherd, R.; Fournier, K.B.; Price, D.; Lee, R.W.; Springer, P.; Peyrusse, O.; Klein, L.

    2002-01-01

    Time-resolved K-shell x-ray spectra are recorded from sub-100 nm aluminum foils irradiated by 150-fs laser pulses at relativistic intensities of Iλ 2 =2x10 18 W μm 2 /cm 2 . The thermal penetration depth is greater than the foil thickness in these targets so that uniform heating takes place at constant density before hydrodynamic motion occurs. The high-contrast, high-intensity laser pulse, broad spectral band, and short time resolution utilized in this experiment permit a simplified interpretation of the dynamical evolution of the radiating matter. The observed spectrum displays two distinct phases. At early time, ≤500 fs after detecting target emission, a broad quasicontinuous spectral feature with strong satellite emission from multiply excited levels is seen. At a later time, the He-like resonance line emission is dominant. The time-integrated data is in accord with previous studies with time resolution greater than 1 ps. The early time satellite emission is shown to be a signature of an initial large area, high density, low-temperature plasma created in the foil by fast electrons accelerated by the intense radiation field in the laser spot. We conclude that, because of this early time phenomenon and contrary to previous predictions, a short, high-intensity laser pulse incident on a thin foil does not create a uniform hot and dense plasma. The heating mechanism has been studied as a function of foil thickness, laser pulse length, and intensity. In addition, the spectra are found to be in broad agreement with a hydrodynamic expansion code postprocessed by a collisional-radiative model based on superconfiguration average rates and on the unresolved transition array formalism

  16. The German 2020 Energy Turnaround Index featuring a special focus on economic efficiency; Energiewende-Index Deutschland 2020. Fokusthema Wirtschaftlichkeit

    Energy Technology Data Exchange (ETDEWEB)

    Vahlenkamp, Thomas [McKinsey and Company, Duesseldorf (Germany); Gohl, Matthias [McKinsey and Company, Berlin (Germany)

    2012-12-15

    The decision to raise the levy imposed by the Renewable Energies Law has kindled the discussion as to how the energy turnaround can best be implemented and made affordable in the first place. The search for solutions should be founded on as full a picture of the situation as possible as well as a fact base shared by all. The aspiration and purpose of the German 2020 Energy Turnaround Index created by McKinsey and Company is to create precisely such a fact base. Every 3 months the index gives an update on the status of the energy turnaround based on 15 indicators. The present update additionally takes a closer look at the aspect of economic efficiency, which together with climate and environment protection and security of supply forms the triad of imperatives driving the energy turnaround.

  17. Highly efficient indoor air purification using adsorption-enhanced-photocatalysis-based microporous TiO2 at short residence time.

    Science.gov (United States)

    Lv, Jinze; Zhu, Lizhong

    2013-01-01

    A short residence time is a key design parameter for the removal of organic pollutants in catalyst-based indoor air purification systems. In this study, we synthesized a series of TiO2 with different micropore volumes and studied their removal efficiency of indoor carbonyl pollutants at a short residence time. Our results indicated that the superior adsorption capability of TiO2 with micropores improved its performance in the photocatalytic degradation of cyclohexanone, while the photocatalytic removal of the pollutant successfully kept porous TiO2 from becoming saturated. When treated with 1 mg m(-3) cyclohexanone at a relatively humidity of 18%, the adsorption amount on microporous TiO2 was 5.4-7.9 times higher than that on P25. Removal efficiency via photocatalysis followed'the same order as the adsorption amount: TiO2-5 > TiO2-20 > TiO2-60 > TiO2-180 > P25. The advantage of microporous TiO2 over P25 became more pronounced when the residence time declined from 0.072 to 0.036 s. Moreover, as the concentration of cyclohexanone deceased from 1000 ppb to 500 ppb, removal efficiency by microporous TiO2 increased more rapidly than P25.

  18. Turnaround in an aged persons' mental health service in crisis: a case study of organisational renewal.

    Science.gov (United States)

    Stafrace, Simon; Lilly, Alan

    2008-08-01

    This case study demonstrates how leadership was harnessed to turn around a decline in the performance of an aged persons' mental health service - the Namarra Nursing Home at Caulfield General Medical Centre in Melbourne, Australia. In 2000 the nursing home faced a crisis of public confidence due to failings in the management of quality, clinical risk and human resources within the service. These problems reflected structural and operational shortcomings in the clinical directorate and wider organisation. In this article, we detail the process of turnaround from the perspective of senior executive managers with professional and operational responsibility for the service. This turnaround required attention to local clinical accountability and transformation of the mental health program from a collocated but operationally isolated service to one integrated within the governance structures of the auspicing organisation.

  19. ECJ judges read the morning papers. Explaining the turnaround of European citizenship jurisprudence

    DEFF Research Database (Denmark)

    Blauberger, Michael; Heindlmaier, Anita; Kramer, Dion

    2018-01-01

    . While the ECJ extended EU citizens’ rights even against strong opposition by member state governments, its recent shift reflects changes in the broader political context, i.e. the politicisation of free movement in the European Union (EU). The article theorizes Court responsiveness to politicisation......Recent jurisprudence of the European Court of Justice (ECJ) marks a striking shift towards a more restrictive interpretation of EU citizens’ rights. The Court’s turnaround is not only highly relevant for practical debates about ‘Social Europe’ or ‘welfare migration’, but also enlightening from...... a more general, theoretical viewpoint. Several recent studies on the ECJ have argued that the Court is largely constrained by member state governments’ threats of legislative override and non-compliance. We show that an additional mechanism is necessary to explain the Court’s turnaround on citizenship...

  20. Is the travel time of private roads too short, too long, or just right?

    NARCIS (Netherlands)

    van den Berg, V.A.C.; Verhoef, E.T.

    2012-01-01

    We consider price and service-quality setting in oligopolistic markets for congestible services, applied to the case of private roads. Previous studies show that parallel competitors set a volume/capacity ratio (and thereby a travel time or service quality) that is socially optimal if they take the

  1. Short time window for transmissibility of African swine fever virus from a contaminated environment

    DEFF Research Database (Denmark)

    Olesen, A S; Lohse, L; Boklund, A.

    2018-01-01

    pens after 3, 5 or 7 days did not develop any signs of ASFV infection and no viral DNA was detected in blood samples obtained from these pigs within the following 3 weeks. Thus, it was shown that exposure of pigs to an environment contaminated with ASFV can result in infection. However, the time window...

  2. The Estimation of Short Time Intervals as a Function of Age and Metronome Pacing.

    Science.gov (United States)

    Kline, Donald W.; And Others

    1980-01-01

    The time judgments of the older participants were significantly and systematically determined by a metronome rate. Results are consistent with the notion of increased field-dependence among older persons and suggest that their greater social conformity and their inability to ignore irrelevant stimuli might also be explicable. (Author)

  3. Short-time existence of solutions for mean-field games with congestion

    KAUST Repository

    Gomes, Diogo A.; Voskanyan, Vardan K.

    2015-01-01

    We consider time-dependent mean-field games with congestion that are given by a Hamilton–Jacobi equation coupled with a Fokker–Planck equation. These models are motivated by crowd dynamics in which agents have difficulty moving in high-density areas

  4. Comparison Groups in Short Interrupted Time-Series: An Illustration Evaluating No Child Left Behind

    Science.gov (United States)

    Wong, Manyee; Cook, Thomas D.; Steiner, Peter M.

    2009-01-01

    Interrupted time-series (ITS) are often used to assess the causal effect of a planned or even unplanned shock introduced into an on-going process. The pre-intervention slope is supposed to index the causal counterfactual, and deviations from it in mean, slope or variance are used to indicate an effect. However, a secure causal inference is only…

  5. Short-time effect of heavy metals upon microbial community activity

    International Nuclear Information System (INIS)

    Wang Fei; Yao Jun; Si Yang; Chen Huilun; Russel, Mohammad; Chen Ke; Qian Yiguang; Zaray, Gyula; Bramanti, Emilia

    2010-01-01

    Microcalorimetry was applied to assess and compare the toxic effect of heavy metals, such as As, Cu, Cd, Cr, Co, Pb and Zn, on the soil microbial activities and community. About 1.0 g soil spiked 5.0 mg glucose and 5.0 mg ammonium sulfate, the microbial activities were recorded as power-time curves, and their indices, microbial growth rate constant k, total heat evolution Q T , metabolic enthalpy ΔH met and mass specific heat rate J Q/S , were calculated. Comparing these thermodynamic parameters associated with growth yield, a general order of toxicity to the soil was found to be Cr > Pb > As > Co > Zn > Cd > Cu. When soil was exposed to heavy metals, the amount of bacteria and fungi decreased with the incubation time, and the bacterial number diminished sharply. It illustrates that fungi are more tolerant, and bacteria-fungi ratio would be altered under metal stress. To determine the status of the glucose consumed, a glucose biosensor with eggshell membrane was used to measure the remaining glucose in soil sample. Results showed that the time at which glucose was consumed completely was agreed with the microcalorimetric time to a large extent, and depended on the toxicity of heavy metals as well.

  6. Short-time effect of heavy metals upon microbial community activity.

    Science.gov (United States)

    Wang, Fei; Yao, Jun; Si, Yang; Chen, Huilun; Russel, Mohammad; Chen, Ke; Qian, Yiguang; Zaray, Gyula; Bramanti, Emilia

    2010-01-15

    Microcalorimetry was applied to assess and compare the toxic effect of heavy metals, such as As, Cu, Cd, Cr, Co, Pb and Zn, on the soil microbial activities and community. About 1.0 g soil spiked 5.0mg glucose and 5.0mg ammonium sulfate, the microbial activities were recorded as power-time curves, and their indices, microbial growth rate constant k, total heat evolution Q(T), metabolic enthalpy Delta H(met) and mass specific heat rate J(Q/S), were calculated. Comparing these thermodynamic parameters associated with growth yield, a general order of toxicity to the soil was found to be Cr>Pb>As>Co>Zn>Cd>Cu. When soil was exposed to heavy metals, the amount of bacteria and fungi decreased with the incubation time, and the bacterial number diminished sharply. It illustrates that fungi are more tolerant, and bacteria-fungi ratio would be altered under metal stress. To determine the status of the glucose consumed, a glucose biosensor with eggshell membrane was used to measure the remaining glucose in soil sample. Results showed that the time at which glucose was consumed completely was agreed with the microcalorimetric time to a large extent, and depended on the toxicity of heavy metals as well.

  7. Short-time effect of heavy metals upon microbial community activity

    Energy Technology Data Exchange (ETDEWEB)

    Wang Fei [Key Laboratory of Biogeology and Environmental Geology of Chinese Ministry of Education and Sino-Hungarian Joint Laboratory of Environmental Science and Health and School of Environmental Sciences, China University of Geosciences, 430074 Wuhan (China); Yao Jun, E-mail: yaojun@cug.edu.cn [Key Laboratory of Biogeology and Environmental Geology of Chinese Ministry of Education and Sino-Hungarian Joint Laboratory of Environmental Science and Health and School of Environmental Sciences, China University of Geosciences, 430074 Wuhan (China); Si Yang; Chen Huilun; Russel, Mohammad; Chen Ke; Qian Yiguang [Key Laboratory of Biogeology and Environmental Geology of Chinese Ministry of Education and Sino-Hungarian Joint Laboratory of Environmental Science and Health and School of Environmental Sciences, China University of Geosciences, 430074 Wuhan (China); Zaray, Gyula [Department of Chemical Technology and Environmental Chemistry, Eoetvoes University, H-1518 Budapest, P.O. Box 32 (Hungary); Bramanti, Emilia [Laboratory of Instrumental Analytical Chemistry, Institute for Chemical and Physical Processes, Area di Ricerca, Via G. Moruzzi 1, 56124 Pisa (Italy)

    2010-01-15

    Microcalorimetry was applied to assess and compare the toxic effect of heavy metals, such as As, Cu, Cd, Cr, Co, Pb and Zn, on the soil microbial activities and community. About 1.0 g soil spiked 5.0 mg glucose and 5.0 mg ammonium sulfate, the microbial activities were recorded as power-time curves, and their indices, microbial growth rate constant k, total heat evolution Q{sub T}, metabolic enthalpy {Delta}H{sub met} and mass specific heat rate J{sub Q/S}, were calculated. Comparing these thermodynamic parameters associated with growth yield, a general order of toxicity to the soil was found to be Cr > Pb > As > Co > Zn > Cd > Cu. When soil was exposed to heavy metals, the amount of bacteria and fungi decreased with the incubation time, and the bacterial number diminished sharply. It illustrates that fungi are more tolerant, and bacteria-fungi ratio would be altered under metal stress. To determine the status of the glucose consumed, a glucose biosensor with eggshell membrane was used to measure the remaining glucose in soil sample. Results showed that the time at which glucose was consumed completely was agreed with the microcalorimetric time to a large extent, and depended on the toxicity of heavy metals as well.

  8. Physiological Correlations with Short, Medium, and Long Cycling Time-Trial Performance

    Science.gov (United States)

    Borszcz, Fernando K.; Tramontin, Artur F.; de Souza, Kristopher M.; Carminatti, Lorival J.; Costa, Vitor P.

    2018-01-01

    Purpose: Several studies have demonstrated that physiological variables predict cycling endurance performance. However, it is still unclear whether the predictors will change over different performance durations. The aim of this study was to assess the correlations between physiological variables and cycling time trials with different durations.…

  9. D1.4 -- Short Report on Models That Incorporate Non-stationary Time Variant Effects

    DEFF Research Database (Denmark)

    Lostanlen, Yves; Pedersen, Troels; Steinboeck, Gerhard

    -to-indoor environments are presented. Furthermore, the impact of human activity on the time variation of the radio channel is investigated and first simulation results are presented. Movement models, which include realistic interaction between nodes, are part of current research activities....

  10. Like a hotel, but boring: users' experience with short-time community-based residential aftercare.

    Science.gov (United States)

    Roos, Eirik; Bjerkeset, Ottar; Svavarsdóttir, Margrét Hrönn; Steinsbekk, Aslak

    2017-12-16

    The discharge process from hospital to home for patients with severe mental illness (SMI) is often complex, and most are in need of tailored and coordinated community services at home. One solution is to discharge patients to inpatient short-stay community residential aftercare (CRA). The aim of this study was to explore how patients with SMI experience a stay in CRA established in a City in Central Norway. A descriptive qualitative study with individual interviews and a group interview with 13 persons. The CRA aims to improve the discharge process from hospital to independent supported living by facilitating the establishment of health and social services and preparing the patients. The philosophy is to help patients use community resources by e.g. not offering any organized in-house activities. The main question in the interviews was "How have you experienced the stay at the CRA?" The interviews were analyzed with a thematic approach using systematic text condensation. The participants experienced the stay at the CRA "Like a hotel" but also boring, due to the lack of organized in-house activities. The patients generally said they were not informed about the philosophy of the CRA before the stay. The participants had to come up with activities outside the CRA and said they got active help from the staff to do so; some experienced this as positive, whereas others wanted more organized in-house activities like they were used to from mental health hospital stays. Participants described the staff in the CRA to be helpful and forthcoming, but they did not notice the staff being active in organizing the aftercare. The stay at the CRA was experienced as different from other services, with more freedom and focus on self-care, and lack of in-house activities. This led to increased self-activity among the patients, but some wanted more in-house activities. To prepare the patients better for the stay at the CRA, more information about the philosophy is needed in the pre

  11. Inducement and responsibility in the energy turnaround; Veranlassung und Verantwortung bei der Energiewende

    Energy Technology Data Exchange (ETDEWEB)

    Loewer, Wolfgang (ed.)

    2013-07-01

    The book includes several contributions concerning the Bonn discussion on energy legislation (volume 7): inducement and responsibility -in terms of constitutional law; between Europe and re-regulation - what is the regulation framework? Continuity requirement as legislative action directive; the future of the nuclear fuel tax after the nuclear phaseout - problems of the constitutional finance and the European tax legislation, strategy and energy markets; regulatory challenges in the realization of the energy turnaround policy.

  12. Three-factor models versus time series models: quantifying time-dependencies of interactions between stimuli in cell biology and psychobiology for short longitudinal data.

    Science.gov (United States)

    Frank, Till D; Kiyatkin, Anatoly; Cheong, Alex; Kholodenko, Boris N

    2017-06-01

    Signal integration determines cell fate on the cellular level, affects cognitive processes and affective responses on the behavioural level, and is likely to be involved in psychoneurobiological processes underlying mood disorders. Interactions between stimuli may subjected to time effects. Time-dependencies of interactions between stimuli typically lead to complex cell responses and complex responses on the behavioural level. We show that both three-factor models and time series models can be used to uncover such time-dependencies. However, we argue that for short longitudinal data the three factor modelling approach is more suitable. In order to illustrate both approaches, we re-analysed previously published short longitudinal data sets. We found that in human embryonic kidney 293 cells cells the interaction effect in the regulation of extracellular signal-regulated kinase (ERK) 1 signalling activation by insulin and epidermal growth factor is subjected to a time effect and dramatically decays at peak values of ERK activation. In contrast, we found that the interaction effect induced by hypoxia and tumour necrosis factor-alpha for the transcriptional activity of the human cyclo-oxygenase-2 promoter in HEK293 cells is time invariant at least in the first 12-h time window after stimulation. Furthermore, we applied the three-factor model to previously reported animal studies. In these studies, memory storage was found to be subjected to an interaction effect of the beta-adrenoceptor agonist clenbuterol and certain antagonists acting on the alpha-1-adrenoceptor / glucocorticoid-receptor system. Our model-based analysis suggests that only if the antagonist drug is administer in a critical time window, then the interaction effect is relevant. © The authors 2016. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

  13. Radionuclide inventories for short run-time space nuclear reactor systems

    International Nuclear Information System (INIS)

    Coats, R.L.

    1993-01-01

    Space Nuclear Reactor Systems, especially those used for propulsion, often have expected operation run times much shorter than those for land-based nuclear power plants. This produces substantially different radionuclide inventories to be considered in the safety analyses of space nuclear systems. This presentation describes an analysis utilizing ORIGEN2 and DKPOWER to provide comparisons among representative land-based and space systems. These comparisons enable early, conceptual considerations of safety issues and features in the preliminary design phases of operational systems, test facilities, and operations by identifying differences between the requirements for space systems and the established practice for land-based power systems. Early indications are that separation distance is much more effective as a safety measure for space nuclear systems than for power reactors because greater decay of the radionuclide activity occurs during the time to transport the inventory a given distance. In addition, the inventories of long-lived actinides are very low for space reactor systems

  14. Decreasing Postanesthesia Care Unit to Floor Transfer Times to Facilitate Short Stay Total Joint Replacements.

    Science.gov (United States)

    Sibia, Udai S; Grover, Jennifer; Turcotte, Justin J; Seanger, Michelle L; England, Kimberly A; King, Jennifer L; King, Paul J

    2018-04-01

    We describe a process for studying and improving baseline postanesthesia care unit (PACU)-to-floor transfer times after total joint replacements. Quality improvement project using lean methodology. Phase I of the investigational process involved collection of baseline data. Phase II involved developing targeted solutions to improve throughput. Phase III involved measured project sustainability. Phase I investigations revealed that patients spent an additional 62 minutes waiting in the PACU after being designated ready for transfer. Five to 16 telephone calls were needed between the PACU and the unit to facilitate each patient transfer. The most common reason for delay was unavailability of the unit nurse who was attending to another patient (58%). Phase II interventions resulted in transfer times decreasing to 13 minutes (79% reduction, P care at other institutions. Copyright © 2016 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

  15. A short note on the mean exit time of the Brownian motion

    Science.gov (United States)

    Cadeddu, Lucio; Farina, Maria Antonietta

    We investigate the functional Ω↦ℰ(Ω) where Ω runs through the set of compact domains of fixed volume v in any Riemannian manifold (M,g) and where ℰ(Ω) is the mean exit time from Ω of the Brownian motion. We give an alternative analytical proof of a well-known fact on its critical points proved by McDonald: the critical points of ℰ(Ω) are harmonic domains.

  16. Antipersistent dynamics in short time scale variability of self-potential signals

    OpenAIRE

    Cuomo, V.; Lanfredi, M.; Lapenna, V.; Macchiato, M.; Ragosta, M.; Telesca, L.

    2000-01-01

    Time scale properties of self-potential signals are investigated through the analysis of the second order structure function (variogram), a powerful tool to investigate the spatial and temporal variability of observational data. In this work we analyse two sequences of self-potential values measured by means of a geophysical monitoring array located in a seismically active area of Southern Italy. The range of scales investigated goes from a few minutes to several days. It is shown that signal...

  17. Rapid growth, early maturation and short generation time in African annual fishes

    Czech Academy of Sciences Publication Activity Database

    Blažek, Radim; Polačik, Matej; Reichard, Martin

    2013-01-01

    Roč. 4, č. 24 (2013), s. 24 ISSN 2041-9139 R&D Projects: GA ČR(CZ) GAP506/11/0112 Institutional support: RVO:68081766 Keywords : extreme life history * annual fish * explosive growth * rapid maturation * generation time * killifish * diapause * vertebrate * reaction norm * Savanna Subject RIV: EG - Zoology Impact factor: 3.104, year: 2013 http://www.evodevojournal.com/content/4/1/24

  18. Time-Series Prediction: Application to the Short-Term Electric Energy Demand

    OpenAIRE

    Troncoso Lora, Alicia; Riquelme Santos, Jesús Manuel; Riquelme Santos, José Cristóbal; Gómez Expósito, Antonio; Martínez Ramos, José Luis

    2003-01-01

    This paper describes a time-series prediction method based on the kNN technique. The proposed methodology is applied to the 24-hour load forecasting problem. Also, based on recorded data, an alternative model is developed by means of a conventional dynamic regression technique, where the parameters are estimated by solving a least squares problem. Finally, results obtained from the application of both techniques to the Spanish transmission system are compared in terms of maximum, average and ...

  19. A Short Proof of the Large Time Energy Growth for the Boussinesq System

    Science.gov (United States)

    Brandolese, Lorenzo; Mouzouni, Charafeddine

    2017-10-01

    We give a direct proof of the fact that the L^p-norms of global solutions of the Boussinesq system in R^3 grow large as t→ ∞ for 1R+× R3. In particular, the kinetic energy blows up as \\Vert u(t)\\Vert _2^2˜ ct^{1/2} for large time. This contrasts with the case of the Navier-Stokes equations.

  20. Stress and Fatigue Management Using Balneotherapy in a Short-Time Randomized Controlled Trial

    OpenAIRE

    Rapolienė, Lolita; Razbadauskas, Artūras; Sąlyga, Jonas; Martinkėnas, Arvydas

    2016-01-01

    Objective. To investigate the influence of high-salinity geothermal mineral water on stress and fatigue. Method. 180 seamen were randomized into three groups: geothermal (65), music (50), and control (65). The geothermal group was administered 108?g/L salinity geothermal water bath for 2 weeks five times a week. Primary outcome was effect on stress and fatigue. Secondary outcomes were the effect on cognitive function, mood, and pain. Results. The improvements after balneotherapy were a reduct...

  1. Antipersistent dynamics in short time scale variability of self-potential signals

    Directory of Open Access Journals (Sweden)

    M. Ragosta

    2000-06-01

    Full Text Available Time scale properties of self-potential signals are investigated through the analysis of the second order structure function (variogram, a powerful tool to investigate the spatial and temporal variability of observational data. In this work we analyse two sequences of self-potential values measured by means of a geophysical monitoring array located in a seismically active area of Southern Italy. The range of scales investigated goes from a few minutes to several days. It is shown that signal fluctuations are characterised by two time scale ranges in which self-potential variability appears to follow slightly different dynamical behaviours. Results point to the presence of fractal, non stationary features expressing a long term correlation with scaling coefficients which are the clue of stabilising mechanisms. In the scale ranges in which the series show scale invariant behaviour, self-potentials evolve like fractional Brownian motions with anticorrelated increments typical of processes regulated by negative feedback mechanisms (antipersistence. On scales below about 6 h the strength of such an antipersistence appears to be slightly greater than that observed on larger time scales where the fluctuations are less efficiently stabilised.

  2. Effect of parameter calculation in direct estimation of the Lyapunov exponent in short time series

    Directory of Open Access Journals (Sweden)

    A. M. López Jiménez

    2002-01-01

    Full Text Available The literature about non-linear dynamics offers a few recommendations, which sometimes are divergent, about the criteria to be used in order to select the optimal calculus parameters in the estimation of Lyapunov exponents by direct methods. These few recommendations are circumscribed to the analysis of chaotic systems. We have found no recommendation for the estimation of λ starting from the time series of classic systems. The reason for this is the interest in distinguishing variability due to a chaotic behavior of determinist dynamic systems of variability caused by white noise or linear stochastic processes, and less in the identification of non-linear terms from the analysis of time series. In this study we have centered in the dependence of the Lyapunov exponent, obtained by means of direct estimation, of the initial distance and the time evolution. We have used generated series of chaotic systems and generated series of classic systems with varying complexity. To generate the series we have used the logistic map.

  3. Short-term dispersal response of an endangered Australian lizard varies with time of year.

    Directory of Open Access Journals (Sweden)

    Mehregan Ebrahimi

    Full Text Available Dispersal is an important component in the demography of animal populations. Many animals show seasonal changes in their tendency to disperse, reflecting changes in resource availability, mating opportunities, or in population age structure at the time when new offspring enter the population. Understanding when and why dispersal occurs can be important for the management of endangered species. The pygmy bluetongue lizard is an endangered Australian species that occupies and defends single burrow refuges for extended periods of time, rarely moving far from the burrow entrance. However, previous pitfall trapping data have suggested movement of adult males in spring and of juveniles in autumn of each year. In the current study we compared behaviours of adult lizards each month, over the spring-summer activity period over two consecutive field seasons, to provide deeper understanding of the seasonal dispersal pattern. We released adult pygmy bluetongue lizards into a central area, provided with artificial burrows, within large enclosures, and monitored the behaviour and movements of the released lizards over a four day period. There was a consistent decline in time spent basking, amount of movement around burrow entrances, and rates of dispersal from the central release area from early spring to late summer. Results could be relevant to understanding and managing natural populations and for any translocation attempts of this endangered lizard species.

  4. Short-time dynamics of phenylene-rings in bisphenol based engineering thermoplastics

    International Nuclear Information System (INIS)

    Arrese-Igor, S.; Arbe, A.; Alegria, A.; Colmenero, J.; Frick, B.

    2003-01-01

    We have recently performed one of the first approaches by means of quasielastic neutron scattering (QENS) to the problem of identifying the molecular motions giving rise to the secondary relaxations of engineering thermoplastics. Preliminary results point to phenylene ring π-flips as the main motion causing the observed quasielastic broadening in the ∼10 -10 -10 -9 s time scale below the glass transition temperature T g . Continuing our study of sub-T g dynamics in these systems by QENS, measurements on polycarbonate (PC) and polysulfone (PSF) with deuterated methyl groups (d6) in the ∼10 -13 -10 -11 s time scale have been performed. The intermediate scattering function shows a smooth second decay in addition to that of vibrations and 'fast dynamics' at T > or approx. 200 K. The extrapolation of phenylene π-flip motion to faster times does not explain the decay observed. However, a non-negligible contribution of π-flips at T≥350 K in PCd6 is noticeable, whereas for PSFd6 some effect can be inferred above ∼450 K. In the temperature region where the π-flips do not contribute to the spectra we have characterised the signal by assuming a temperature dependent distribution of small angle oscillations of phenylene rings leading to an activation energy of 0.18 eV

  5. Short communication: Pharmacokinetics of intramammary hetacillin in dairy cattle milked 3 times per day.

    Science.gov (United States)

    Lindquist, Danielle A; Baynes, Ronald E; Smith, Geof W

    2015-03-01

    Mastitis remains a critical disease in the dairy industry and the use of intramammary antibiotics plays a critical role in mastitis treatment. Hetacillin is currently approved as an intramammary antibiotic that is used to treat mastitis in dairy cows. It is approved for once a day administration and can be used for a total of 3 d. An increasing number of dairy farms are milking 3 times per day (instead of the traditional 2 times per day) and very little pharmacokinetic data exists on the use of intramammary drugs in a 3×system. The primary purpose of this study was to determine if once a day intramammary infusion of hetacillin is sufficient to maintain therapeutic drug concentrations in cattle milked 3 times per day. Eight Holstein cattle milked 3 times per day were used in this study. After collecting a baseline milk sample, each cow received intramammary infusions of hetacillin in the left front and right rear quarters once a day for 3 d. Milk samples from each of the treated quarters were collected at each milking and frozen until analysis. Milk samples were analyzed for ampicillin concentrations using an ultra-performance liquid chromatography method. All treated quarters had antibiotic concentrations well above the minimum inhibitory concentration (MIC) for gram-positive mastitis pathogens at 8 and 16 h postinfusion. Milk concentrations had fallen well below the MIC by the 24-h period (before the next infusion). All 8 cows in this study consistently had individual quarter milk ampicillin concentrations below the FDA tolerance of 0.01 μg/mL (10 ppb) within 48 h of the last infusion. Based on this study, milk ampicillin concentrations exceed the minimum inhibitory concentration required to inhibit the growth of 90% of organisms (MIC90) for at least 65% of the dosing interval, which is sufficient for once-daily dosing with most cases of gram-positive mastitis. Therefore, intramammary hetacillin should be an effective treatment for the vast majority of gram

  6. Citizen investments in the energy policy turnaround; Buergerinvestitionen in die Energiewende

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    The recently recognisable economical and political developments are characterized by an enormous diversity of simultaneously acting processes. These processes challenge the design and balancing attendance of a complex and intense restructuring. Under this aspect, the brochure under consideration presents the following contributions: (1) Energy policy turnaround, investments by citizens and regional development (Peter Jakubowski); (2) Importance of decentralized participation processes for the acceptance of the development of renewable energies. An environmental psychological consideration (Jan Hildebrand); (3) Advantages of cooperative solutions in the energy policy turnaround (Wolfgang George); (4) Significance and potential of energy cooperatives in Germany. An empiric analysis (Richard Volz); (5) Sustainable investment in the energy policy turnaround with the participation of banks and saving banks (Uwe Greff); (6) Financial participation by citizens. Examples of good practice for investment products such as climate savings certificates, subordinated loans or silent participations (Katrin Gehles); (7) The Jurenergie eG: A citizen energy association on a successful course (Vera Ptacek); (8) Regional value creation effects of different organisational forms in respect of the power generation from biomass (Reinhold Kosfeld).

  7. Where the world stands still: turnaround as a strong test of ΛCDM cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Pavlidou, V.; Tomaras, T.N., E-mail: pavlidou@physics.uoc.gr, E-mail: tomaras@physics.uoc.gr [Department of Physics and ITCP, University of Crete, 71003 Heraklion (Greece)

    2014-09-01

    Our intuitive understanding of cosmic structure formation works best in scales small enough so that isolated, bound, relaxed gravitating systems are no longer adjusting their radius; and large enough so that space and matter follow the average expansion of the Universe. Yet one of the most robust predictions of ΛCDM cosmology concerns the scale that separates these limits: the turnaround radius, which is the non-expanding shell furthest away from the center of a bound structure. We show that the maximum possible value of the turnaround radius within the framework of the ΛCDM model is, for a given mass M, equal to (3GM/Λ c{sup 2}){sup 1/3}, with G Newton's constant and c the speed of light, independently of cosmic epoch, exact nature of dark matter, or baryonic effects. We discuss the possible use of this prediction as an observational test for ΛCDM cosmology. Current data appear to favor ΛCDM over alternatives with local inhomogeneities and no Λ. However there exist several local-universe structures that have, within errors, reached their limiting size. With improved determinations of their turnaround radii and the enclosed mass, these objects may challenge the limit and ΛCDM cosmology.

  8. Where the world stands still: turnaround as a strong test of ΛCDM cosmology

    Science.gov (United States)

    Pavlidou, V.; Tomaras, T. N.

    2014-09-01

    Our intuitive understanding of cosmic structure formation works best in scales small enough so that isolated, bound, relaxed gravitating systems are no longer adjusting their radius; and large enough so that space and matter follow the average expansion of the Universe. Yet one of the most robust predictions of ΛCDM cosmology concerns the scale that separates these limits: the turnaround radius, which is the non-expanding shell furthest away from the center of a bound structure. We show that the maximum possible value of the turnaround radius within the framework of the ΛCDM model is, for a given mass M, equal to (3GM/Λ c2)1/3, with G Newton's constant and c the speed of light, independently of cosmic epoch, exact nature of dark matter, or baryonic effects. We discuss the possible use of this prediction as an observational test for ΛCDM cosmology. Current data appear to favor ΛCDM over alternatives with local inhomogeneities and no Λ. However there exist several local-universe structures that have, within errors, reached their limiting size. With improved determinations of their turnaround radii and the enclosed mass, these objects may challenge the limit and ΛCDM cosmology.

  9. Pricing decision model for new and remanufactured short-life cycle products with time-dependent demand

    Directory of Open Access Journals (Sweden)

    Shu San Gan

    2015-12-01

    Full Text Available In this study we develop a model that optimizes the price for new and remanufactured short life-cycle products where demands are time-dependent and price sensitive. While there has been very few published works that attempt to model remanufacturing decisions for products with short life cycle, we believe that there are many situations where remanufacturing short life cycle products is rewarding economically as well as environmentally. The system that we model consists of a retailer, a manufacturer, and a collector of used product from the end customers. Two different scenarios are evaluated for the system. The first is the independent situation where each party attempts to maximize his/her own total profit and the second is the joint profit model where we optimize the combined total profit for all three members of the supply chain. Manufacturer acts as the Stackelberg leader in the independently optimized scenario, while in the other the intermediate prices are determined by coordinated pricing policy. The results suggest that (i reducing the price of new products during the decline phase does not give better profit for the whole system, (ii the total profit obtained from optimizing each player is lower than the total profit of the integrated model, and (iii speed of change in demand influences the robustness of the prices as well as the total profit gained.

  10. No Clear Association between Impaired Short-Term or Working Memory Storage and Time Reproduction Capacity in Adult ADHD Patients.

    Science.gov (United States)

    Mette, Christian; Grabemann, Marco; Zimmermann, Marco; Strunz, Laura; Scherbaum, Norbert; Wiltfang, Jens; Kis, Bernhard

    2015-01-01

    Altered time reproduction is exhibited by patients with adult attention deficit hyperactivity disorder (ADHD). It remains unclear whether memory capacity influences the ability of adults with ADHD to reproduce time intervals. We conducted a behavioral study on 30 ADHD patients who were medicated with methylphenidate, 29 unmedicated adult ADHD patients and 32 healthy controls (HCs). We assessed time reproduction using six time intervals (1 s, 4 s, 6 s, 10 s, 24 s and 60 s) and assessed memory performance using the Wechsler memory scale. The patients with ADHD exhibited lower memory performance scores than the HCs. No significant differences in the raw scores for any of the time intervals (p > .05), with the exception of the variability at the short time intervals (1 s, 4 s and 6 s) (p memory performance (p > .05). We detected no findings indicating that working memory might influence time reproduction in adult patients with ADHD. Therefore, further studies concerning time reproduction and memory capacity among adult patients with ADHD must be performed to verify and replicate the present findings.

  11. No Clear Association between Impaired Short-Term or Working Memory Storage and Time Reproduction Capacity in Adult ADHD Patients.

    Directory of Open Access Journals (Sweden)

    Christian Mette

    Full Text Available Altered time reproduction is exhibited by patients with adult attention deficit hyperactivity disorder (ADHD. It remains unclear whether memory capacity influences the ability of adults with ADHD to reproduce time intervals.We conducted a behavioral study on 30 ADHD patients who were medicated with methylphenidate, 29 unmedicated adult ADHD patients and 32 healthy controls (HCs. We assessed time reproduction using six time intervals (1 s, 4 s, 6 s, 10 s, 24 s and 60 s and assessed memory performance using the Wechsler memory scale.The patients with ADHD exhibited lower memory performance scores than the HCs. No significant differences in the raw scores for any of the time intervals (p > .05, with the exception of the variability at the short time intervals (1 s, 4 s and 6 s (p .05.We detected no findings indicating that working memory might influence time reproduction in adult patients with ADHD. Therefore, further studies concerning time reproduction and memory capacity among adult patients with ADHD must be performed to verify and replicate the present findings.

  12. Microbial inactivation of paprika by a high-temperature short-X time treatment. Influence on color properties.

    Science.gov (United States)

    Almela, Luis; Nieto-Sandoval, José M; Fernández López, José A

    2002-03-13

    High-temperature short-time (HTST) treatments have been used to destroy the bioburden of paprika. With this in mind, we have designed a device to treat samples of paprika with a gas whose temperature, pressure, and composition can be selected. Temperatures and treatment times ranged from 130 to 170 degrees C and 4 to 6 s, respectively. The survival of the most commonly found microorganisms in paprika and any alteration in extractable and superficial color were examined. Data showed that the optimum HTST conditions were 145 degrees C, 1.5 kg/cm2 of overpressure, 6 s operation time, and a thermal fluid of saturated steam. No microbial growth was detected during storage after thermal treatment. To minimize the color losses, treated (HTST) paprika samples should be kept under refrigeration.

  13. Performance Analysis of the Enhanced DSR Routing Protocol for the Short Time Disconnected MANET to the OPNET Modeler

    Directory of Open Access Journals (Sweden)

    PAPAJ Ján

    2013-05-01

    Full Text Available Disconnected mobile ad-hoc networks (MANET are very important areas of the research. In this article, the performance analysis of the enhanced dynamic source routing protocol (OPP_DSR is introduced. This modification enables the routing process in the case when there are no connections to other mobile nodes. It also will enable the routing mechanisms when the routes, selected by routing mechanisms, are disconnected for some time. Disconnection can be for a short time and standard routing protocol DSR cannot reflect on this situation.The main idea is based on opportunistic forwarding where the nodes not only forward data but it's stored in the cache during long time. The network parameters throughput, routing load and are analysed.

  14. [Effect of short-time drought process on denitrifying bacteria abundance and N2O emission in paddy soil].

    Science.gov (United States)

    Lu, Jing; Liu, Jin-Bo; Sheng, Rong; Liu, Yi; Chen, An-Lei; Wei, Wen-Xue

    2014-10-01

    In order to investigate the impact of drying process on greenhouse gas emissions and denitrifying microorganisms in paddy soil, wetting-drying process was simulated in laboratory conditions. N2O flux, redox potential (Eh) were monitored and narG- and nosZ-containing denitrifiers abundances were determined by real-time PCR. N2O emission was significantly increased only 4 h after drying process began, and it was more than 6 times of continuous flooding (CF) at 24 h. In addition, narG and nosZ gene abundances were increased rapidly with the drying process, and N2O emission flux was significantly correlated with narG gene abundance (P driving microorganisms which caused the N2O emission in the short-time drought process in paddy soil.

  15. Analysis of short time-space range seismicity patterns in Italy

    Directory of Open Access Journals (Sweden)

    M. Imotof

    1997-06-01

    Full Text Available In our paper we analyze the data base obtained from the observations of the Italian Seismological Network from 1975 to 1994 by using a simple algotithm to determine the rate of occurrence of seismic events condi- tioned by the occurrence of previous events after a period of quiescence. The number of observed pairs of earthquakes depends on several parameters: the magnitude threshold of the two events, the spatial and tempo- ral ranges of the quiescence period preceding the first (non aftershock event, the time elapsed between the first and the second events and the spatial dimension of the alarm area. The Akaike information criterion was adopted to assess the optimal set of space-time parameters used in the definition of non-aftershock (events not related to a stronger previous one. In Central Italy, the rate of M ³3.8 earthquakes preceded by at least one M ~ 3.3 foreshock within 14.1 km and 2 days is 30%, while the rate of M ~ 3.3 earthquakes followed by a M ~ 3.8 mainshock in the same space time range is 7%. We observed that the probability that an earthquake of magnitude MI will be followed by an earthquake of magnitude M2 (success rate fits the law log À = a+b (Mi -M2 with b approximately equal to l. By computing the success rate for given values of magnitude threshold of the first and the second events over a dense grid of spatial coordinates, we obtained maps of this feature over the investigated area. The results of this process document variations larger than a factor of five in the success rate over the Italian territory.

  16. Five-Kilometers Time Trial: Preliminary Validation of a Short Test for Cycling Performance Evaluation.

    Science.gov (United States)

    Dantas, Jose Luiz; Pereira, Gleber; Nakamura, Fabio Yuzo

    2015-09-01

    The five-kilometer time trial (TT5km) has been used to assess aerobic endurance performance without further investigation of its validity. This study aimed to perform a preliminary validation of the TT5km to rank well-trained cyclists based on aerobic endurance fitness and assess changes of the aerobic endurance performance. After the incremental test, 20 cyclists (age = 31.3 ± 7.9 years; body mass index = 22.7 ± 1.5 kg/m(2); maximal aerobic power = 360.5 ± 49.5 W) performed the TT5km twice, collecting performance (time to complete, absolute and relative power output, average speed) and physiological responses (heart rate and electromyography activity). The validation criteria were pacing strategy, absolute and relative reliability, validity, and sensitivity. Sensitivity index was obtained from the ratio between the smallest worthwhile change and typical error. The TT5km showed high absolute (coefficient of variation 0.95) reliability of performance variables, whereas it presented low reliability of physiological responses. The TT5km performance variables were highly correlated with the aerobic endurance indices obtained from incremental test (r > 0.70). These variables showed adequate sensitivity index (> 1). TT5km is a valid test to rank the aerobic endurance fitness of well-trained cyclists and to differentiate changes on aerobic endurance performance. Coaches can detect performance changes through either absolute (± 17.7 W) or relative power output (± 0.3 W.kg(-1)), the time to complete the test (± 13.4 s) and the average speed (± 1.0 km.h(-1)). Furthermore, TT5km performance can also be used to rank the athletes according to their aerobic endurance fitness.

  17. Vision-based online vibration estimation of the in-vessel inspection flexible robot with short-time Fourier transformation

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Hesheng [Key Laboratory of System Control and Information Processing, Ministry of Education of China (China); Department of Automation, Shanghai Jiao Tong University, Shanghai 200240 (China); Chen, Weidong, E-mail: wdchen@sjtu.edu.cn [Key Laboratory of System Control and Information Processing, Ministry of Education of China (China); Department of Automation, Shanghai Jiao Tong University, Shanghai 200240 (China); Xu, Lifei; He, Tao [Key Laboratory of System Control and Information Processing, Ministry of Education of China (China); Department of Automation, Shanghai Jiao Tong University, Shanghai 200240 (China)

    2015-10-15

    Highlights: • Vision-based online vibration estimation method for a flexible arm is proposed. • The vibration signal is obtained by image processing in unknown environments. • Vibration parameters are estimated by short-time Fourier transformation. - Abstract: The vibration should be suppressed if it happens during the motion of a flexible robot or under the influence of external disturbance caused by its structural features and material properties, because the vibration may affect the positioning accuracy and image quality. In Tokamak environment, we need to get the real-time vibration information on vibration suppression of robotic arm, however, some sensors are not allowed in the extreme Tokamak environment. This paper proposed a vision-based method for online vibration estimation of a flexible manipulator, which is achieved by utilizing the environment image information from the end-effector camera to estimate its vibration. Short-time Fourier Transformation with adaptive window length method is used to estimate vibration parameters of non-stationary vibration signals. Experiments with one-link flexible manipulator equipped with camera are carried out to validate the feasibility of this method in this paper.

  18. Gamma spectrometric characterization of short cooling time nuclear spent fuels using hemispheric CdZnTe detectors

    CERN Document Server

    Lebrun, A; Szabó, J L; Arenas-Carrasco, J; Arlt, R; Dubreuil, A; Esmailpur-Kazerouni, K

    2000-01-01

    After years of cooling, nuclear spent fuel gamma emissions are mainly due to caesium isotopes which are emitters at 605, 662 and 796-801 keV. Extensive work has been done on such fuels using various CdTe or CdZnTe probes. When fuels have to be measured after short cooling time (during NPP outage) the spectrum is much more complex due to the important contributions of niobium and zirconium in the 700 keV range. For the first time in a nuclear power plant, four spent fuels of the Kozloduy VVER reactor no 4 were measured during outage, 37 days after shutdown of the reactor. In such conditions, good resolution is of particular interest, so a 20 mm sup 3 hemispheric crystal was used with a resolution better than 7 keV at 662 keV. This paper presents the experimental device and analyzes the results which show that CdZnTe commercially available detectors enabled us to perform a semi-quantitative determination of the burn-up after a short cooling time. In addition, it is discussed how a burn-up evolution code (CESAR)...

  19. Vision-based online vibration estimation of the in-vessel inspection flexible robot with short-time Fourier transformation

    International Nuclear Information System (INIS)

    Wang, Hesheng; Chen, Weidong; Xu, Lifei; He, Tao

    2015-01-01

    Highlights: • Vision-based online vibration estimation method for a flexible arm is proposed. • The vibration signal is obtained by image processing in unknown environments. • Vibration parameters are estimated by short-time Fourier transformation. - Abstract: The vibration should be suppressed if it happens during the motion of a flexible robot or under the influence of external disturbance caused by its structural features and material properties, because the vibration may affect the positioning accuracy and image quality. In Tokamak environment, we need to get the real-time vibration information on vibration suppression of robotic arm, however, some sensors are not allowed in the extreme Tokamak environment. This paper proposed a vision-based method for online vibration estimation of a flexible manipulator, which is achieved by utilizing the environment image information from the end-effector camera to estimate its vibration. Short-time Fourier Transformation with adaptive window length method is used to estimate vibration parameters of non-stationary vibration signals. Experiments with one-link flexible manipulator equipped with camera are carried out to validate the feasibility of this method in this paper.

  20. Devolatilization kinetics of woody biomass at short residence times and high heating rates and peak temperatures

    DEFF Research Database (Denmark)

    Johansen, Joakim M.; Gadsbøll, Rasmus; Thomsen, Jesper

    2016-01-01

    This work combines experimental and computational fluid dynamics (CFD) results to derive global kinetics for biomass (pine wood) devolatilization during heating rates on the order of 105Ks-1, bulk flow peak temperatures between 1405 and 1667K, and particle residence times below 0.1s. Experiments......Jmol-1. The accuracy of the derived global kinetics was supported by comparing predictions to experimental results from a 15kW furnace. The work emphasizes the importance of characterizing the temperature history of the biomass particles when deriving pyrolysis kinetics. The present results indicate...

  1. Antimicrobial and antiviral effect of high-temperature short-time (HTST) pasteurization applied to human milk.

    Science.gov (United States)

    Terpstra, Fokke G; Rechtman, David J; Lee, Martin L; Hoeij, Klaske Van; Berg, Hijlkeline; Van Engelenberg, Frank A C; Van't Wout, Angelica B

    2007-03-01

    In the United States, concerns over the transmission of infectious diseases have led to donor human milk generally being subjected to pasteurization prior to distribution and use. The standard method used by North American milk banks is Holder pasteurization (63 degrees C for 30 minutes). The authors undertook an experiment to validate the effects of a high-temperature short-time (HTST) pasteurization process (72 degrees C for 16 seconds) on the bioburden of human milk. It was concluded that HTST is effective in the elimination of bacteria as well as of certain important pathogenic viruses.

  2. Fetal short time variation during labor: a non-invasive alternative to fetal scalp pH measurements?

    OpenAIRE

    Schiermeier, Sven; Reinhard, Joscha; Hatzmann, Hendrike; Zimmermann, Ralf C.; Westhof, Gregor

    2009-01-01

    Objective: To determine whether short time variation (STV) of fetal heart beat correlates with scalp pH measurements during labor. Patients and methods: From 1279 deliveries, 197 women had at least one fetal scalp pH measurement. Using the CTG-Player®, STVs were calculated from the electronically saved cardiotocography (CTG) traces and related to the fetal scalp pH measurements. Results: There was no correlation between STV and fetal scalp pH measurements (r=−0.0592). Conclusions: Fetal ST...

  3. Short-time dynamics of random-bond Potts ferromagnet with continuous self-dual quenched disorders

    OpenAIRE

    Pan, Z. Q.; Ying, H. P.; Gu, D. W.

    2001-01-01

    We present Monte Carlo simulation results of random-bond Potts ferromagnet with the Olson-Young self-dual distribution of quenched disorders in two-dimensions. By exploring the short-time scaling dynamics, we find universal power-law critical behavior of the magnetization and Binder cumulant at the critical point, and thus obtain estimates of the dynamic exponent $z$ and magnetic exponent $\\eta$, as well as the exponent $\\theta$. Our special attention is paid to the dynamic process for the $q...

  4. Application of rat mast cell incubates as a possible short-time test for sensitizing occupational chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Diel, F.; Neidhart, B.; Opree, W.

    1981-08-01

    The direct action of sensitizing occupational chemicals (formaldehyde, phenol, phenylhydrazine, p-aminophenol) on rat mast cells was investigated by determination of histamine using HPLC separation and fluorimetric detection. It turned out that dispersed mast cells from immunized and non-immunized Wistar-rats are more sensitive than small-cut lung tissue slices. Passive cutaneous anaphylaxis was negative after a fortnight sensitizing experiment with the here described occupational chemicals. Short-time tests with rat mast cells reflect anaphylactoid response and are suitable for the screening of sensitizing chemicals.

  5. A short essay on quantum black holes and underlying noncommutative quantized space-time

    International Nuclear Information System (INIS)

    Tanaka, Sho

    2017-01-01

    We emphasize the importance of noncommutative geometry or Lorenz-covariant quantized space-time towards the ultimate theory of quantum gravity and Planck scale physics. We focus our attention on the statistical and substantial understanding of the Bekenstein–Hawking area-entropy law of black holes in terms of the kinematical holographic relation (KHR). KHR manifestly holds in Yang’s quantized space-time as the result of kinematical reduction of spatial degrees of freedom caused by its own nature of noncommutative geometry, and plays an important role in our approach without any recourse to the familiar hypothesis, so-called holographic principle. In the present paper, we find a unified form of KHR applicable to the whole region ranging from macroscopic to microscopic scales in spatial dimension d   =  3. We notice a possibility of nontrivial modification of area-entropy law of black holes which becomes most remarkable in the extremely microscopic system close to Planck scale. (paper)

  6. Control of insects and mites in grain using a high temperature/short time (HTST) technique.

    Science.gov (United States)

    Mourier; Poulsen

    2000-07-01

    Wheat infested with grain mites (Acari) and Sitophilus granarius, and maize infested with Prostephanus truncatus, were exposed to hot air in a CIMBRIA HTST Microline toaster((R)). Inlet temperatures of the hot air were in the range of 150-750 degrees C decreasing to outlet temperatures in the range of 100-300 degrees C during the exposure period. A rotating drum, connected to a natural-gas burner was fed with grain which was in constant movement along the drum and thereby mixed thoroughly during the process. The capacity of the toaster was 1000 kg per hour.Complete control of grain mites and adult S. granarius in wheat was obtained with an inlet temperature of 300-350 degrees C and an average residence time in the drum of 6 s. More than 99% mortality was obtained for all stages of S. granarius with an inlet temperature of 300-350 degrees C and an average exposure period of 40 s. For control of P. truncatus in maize, an inlet temperature of 700 degrees C resulted in a complete disinfestation when the exposure time was 19 s.The reduction in grain moisture content was 0.5-1% at treatments giving 100% control. Germination tests indicate that it is possible to choose a combination of inlet temperatures and exposure periods which effectively kills mites and insects in small grains, without harming the functional properties of the grain.Economy of the method was considered to be competitive with fumigation using phosphine.

  7. Scenario-Based Case Study Analysis of Asteroid Mitigation in the Short Response Time Regime

    Science.gov (United States)

    Seery, B.; Greenaugh, K. C.

    2017-12-01

    Asteroid impact on Earth is a rare but inevitable occurrence, with potentially cataclysmic consequences. If a pending impact is discovered, mitigation options include civil-defense preparations as well as missions to deflect the asteroid and/or robustly disrupt and disperse it to an extent that only a negligible fraction remains on a threatening path (National Research Council's "Defending the Planet," 2010). If discovered with sufficient warning time, a kinetic impactor can deflect smaller objects, but response delays can rule out the option. If a body is too large to deflect by kinetic impactor, or the time for response is insufficient, deflection or disruption can be achieved with a nuclear device. The use of nuclear ablation is considered within the context of current capabilities, requiring no need for nuclear testing. Existing, well-understood devices are sufficient for the largest known Potentially Hazardous Objects (PHOs). The National Aeronautics and Space Administration/Goddard Space Flight Center and the Department of Energy/National Nuclear Security Administration are collaborating to determine the critical characterization issues that define the boundaries for the asteroid-deflection options. Drawing from such work, we examine the timeline for a deflection mission, and how to provide the best opportunity for an impactor to suffice by minimizing the response time. This integrated problem considers the physical process of the deflection method (impact or ablation), along with the spacecraft, launch capability, risk analysis, and the available intercept flight trajectories. Our joint DOE/NASA team has conducted case study analysis of three distinctly different PHOs, on a hypothetical earth impacting trajectory. The size of the design reference bodies ranges from 100 - 500 meters in diameter, with varying physical parameters such as composition, spin state, and metallicity, to name a few. We assemble the design reference of the small body in question using

  8. Short-time, high temperature mechanical testing of electrically conductive materials

    International Nuclear Information System (INIS)

    Marion, R.H.; Karnes, C.H.

    1975-10-01

    Design and performance details are given for a facility which was developed to obtain the mechanical properties of materials under high heating rate or transient temperature conditions and medium strain rates. The system is shown to be applicable to materials possessing electrical resistivities ranging from that of aluminum to that of graphite without taxing the heating capability. Heating rates as high as 2000 0 K/s in graphite are attained under controlled conditions. Methods of measuring temperature and the effects of expected temperature distributions are discussed. A method for measuring strain valid for transient temperature conditions to 3000 0 K is described. Results are presented for the stress-strain behavior of 316 stainless steel and ATJ(S) graphite obtained for heating times of a few seconds. (auth)

  9. Online Identification of a Mechanical System in the Frequency Domain with Short-Time DFT

    Directory of Open Access Journals (Sweden)

    Niko Nevaranta

    2015-07-01

    Full Text Available A proper system identification method is of great importance in the process of acquiring an analytical model that adequately represents the characteristics of the monitored system. While the use of different time-domain online identification techniques has been widely recognized as a powerful approach for system diagnostics, the frequency domain identification techniques have primarily been considered for offline commissioning purposes. This paper addresses issues in the online frequency domain identification of a flexible two-mass mechanical system with varying dynamics, and a particular attention is paid to detect the changes in the system dynamics. An online identification method is presented that is based on a recursive Kalman filter configured to perform like a discrete Fourier transform (DFT at a selected set of frequencies. The experimental online identification results are compared with the corresponding values obtained from the offline-identified frequency responses. The results show an acceptable agreement and demonstrate the feasibility of the proposed identification method.

  10. A short-time scale colloidal system reveals early bacterial adhesion dynamics.

    Directory of Open Access Journals (Sweden)

    Christophe Beloin

    2008-07-01

    Full Text Available The development of bacteria on abiotic surfaces has important public health and sanitary consequences. However, despite several decades of study of bacterial adhesion to inert surfaces, the biophysical mechanisms governing this process remain poorly understood, due, in particular, to the lack of methodologies covering the appropriate time scale. Using micrometric colloidal surface particles and flow cytometry analysis, we developed a rapid multiparametric approach to studying early events in adhesion of the bacterium Escherichia coli. This approach simultaneously describes the kinetics and amplitude of early steps in adhesion, changes in physicochemical surface properties within the first few seconds of adhesion, and the self-association state of attached and free-floating cells. Examination of the role of three well-characterized E. coli surface adhesion factors upon attachment to colloidal surfaces--curli fimbriae, F-conjugative pilus, and Ag43 adhesin--showed clear-cut differences in the very initial phases of surface colonization for cell-bearing surface structures, all known to promote biofilm development. Our multiparametric analysis revealed a correlation in the adhesion phase with cell-to-cell aggregation properties and demonstrated that this phenomenon amplified surface colonization once initial cell-surface attachment was achieved. Monitoring of real-time physico-chemical particle surface properties showed that surface-active molecules of bacterial origin quickly modified surface properties, providing new insight into the intricate relations connecting abiotic surface physicochemical properties and bacterial adhesion. Hence, the biophysical analytical method described here provides a new and relevant approach to quantitatively and kinetically investigating bacterial adhesion and biofilm development.

  11. Short-term forecasting of meteorological time series using Nonparametric Functional Data Analysis (NPFDA)

    Science.gov (United States)

    Curceac, S.; Ternynck, C.; Ouarda, T.

    2015-12-01

    Over the past decades, a substantial amount of research has been conducted to model and forecast climatic variables. In this study, Nonparametric Functional Data Analysis (NPFDA) methods are applied to forecast air temperature and wind speed time series in Abu Dhabi, UAE. The dataset consists of hourly measurements recorded for a period of 29 years, 1982-2010. The novelty of the Functional Data Analysis approach is in expressing the data as curves. In the present work, the focus is on daily forecasting and the functional observations (curves) express the daily measurements of the above mentioned variables. We apply a non-linear regression model with a functional non-parametric kernel estimator. The computation of the estimator is performed using an asymmetrical quadratic kernel function for local weighting based on the bandwidth obtained by a cross validation procedure. The proximities between functional objects are calculated by families of semi-metrics based on derivatives and Functional Principal Component Analysis (FPCA). Additionally, functional conditional mode and functional conditional median estimators are applied and the advantages of combining their results are analysed. A different approach employs a SARIMA model selected according to the minimum Akaike (AIC) and Bayessian (BIC) Information Criteria and based on the residuals of the model. The performance of the models is assessed by calculating error indices such as the root mean square error (RMSE), relative RMSE, BIAS and relative BIAS. The results indicate that the NPFDA models provide more accurate forecasts than the SARIMA models. Key words: Nonparametric functional data analysis, SARIMA, time series forecast, air temperature, wind speed

  12. Time perspective in hereditary cancer: psychometric properties of a short form of the Zimbardo Time Perspective Inventory in a community and clinical sample.

    Science.gov (United States)

    Wakefield, Claire E; Homewood, Judi; Taylor, Alan; Mahmut, Mehmet; Meiser, Bettina

    2010-10-01

    We aimed to assess the psychometric properties of a 25-item short form of the Zimbardo Time Perspective Inventory in a community sample (N = 276) and in individuals with a strong family history of cancer, considering genetic testing for cancer risk (N = 338). In the community sample, individuals with high past-negative or present-fatalistic scores had higher levels of distress, as measured by depression, anxiety, and aggression. Similarly, in the patient sample, past-negative time perspective was positively correlated with distress, uncertainty, and postdecision regret when making a decision about genetic testing. Past-negative-oriented individuals were also more likely to be undecided about, or against, genetic testing. Hedonism was associated with being less likely to read the educational materials they received at their clinic, and fatalism was associated with having lower knowledge levels about genetic testing. The assessment of time perspective in individuals at increased risk of cancer can provide valuable clinical insights. However, further investigation of the psychometric properties of the short form of this scale is warranted, as it did not meet the currently accepted criteria for psychometric validation studies.

  13. Metabolic changes in the normal ageing brain: Consistent findings from short and long echo time proton spectroscopy

    International Nuclear Information System (INIS)

    Gruber, S.; Pinker, K.; Riederer, F.; Chmelik, M.; Stadlbauer, A.; Bittsansky, M.; Mlynarik, V.; Frey, R.; Serles, W.; Bodamer, O.; Moser, E.

    2008-01-01

    Objectives: Sixty three healthy subjects were measured to assess dependence of brain metabolites on age using short- and long echo time spectroscopy in different brain regions. Material and methods: Younger and elderly humans were measured with long echo time (TE = 135 ms) 3D-MR-spectroscopic imaging (MRSI) (10 subjects) and with ultra-short echo (TE = 11 ms) time 2D-MRSI (7 subjects). In addition, results from single voxel 1 H-spectroscopy (TE = 20 ms) of two cohorts of 46 healthy subjects were retrospectively correlated with age. Results: 3D-MR SI revealed reduced NAA/Cr in the older group in the frontal lobe (-22%; p < 0.01), parietal lobe (-28%; p < 0.01) and semiovale (-9%; p < 0.01) compared to the younger group. Cho/Cr was elevated in the semiovale (+35%; p < 0.01) and in the n. lentiformis (+42%; p < 0.01) in the older group. NAA/Cho was reduced in all regions measured, except the thalamus, in the older group compared to the younger group (from -21 to -49%; p < 0.01). 2D-MRSI revealed decreased total NAA (-3.1% per decade; p < 0.01) and NAA/Cr (-3.8% per decade; p < 0.01), increased total Cho (+3.6% per decade; p < 0.01) and Cho/Cr (+4.6% per decade; p < 0.01) and increased total myo-Inositol (mI, +4.7% per decade; p < 0.01) and mI/Cr (+5.4% per decade; p < 0.01) and decreased NAA/Cho (-8% per decade; p < 0.01) in semiovale WM. Results from single voxel spectroscopy revealed a significantly negative correlation of NAA/Cho in frontal (-13% per decade; p < 0.01) and in temporal lobe (-7.4% per decade; p < 0.01) as well as increased total Cr (10% per decade; p < 0.01) in frontal lobe. Other results from single voxel measurements were not significant, but trends were comparable to that from multivoxel spectroscopy. Conclusion: Age-related changes measured with long echo time and short echo time 1H-MRS were comparable and cannot, therefore, be caused by different T2 relaxation times in young and old subjects, as suggested previously

  14. Stress and Fatigue Management Using Balneotherapy in a Short-Time Randomized Controlled Trial

    Science.gov (United States)

    Razbadauskas, Artūras; Sąlyga, Jonas; Martinkėnas, Arvydas

    2016-01-01

    Objective. To investigate the influence of high-salinity geothermal mineral water on stress and fatigue. Method. 180 seamen were randomized into three groups: geothermal (65), music (50), and control (65). The geothermal group was administered 108 g/L salinity geothermal water bath for 2 weeks five times a week. Primary outcome was effect on stress and fatigue. Secondary outcomes were the effect on cognitive function, mood, and pain. Results. The improvements after balneotherapy were a reduction in the number and intensity of stress-related symptoms, a reduction in pain and general, physical, and mental fatigue, and an improvement in stress-related symptoms management, mood, activation, motivation, and cognitive functions with effect size from 0.8 to 2.3. In the music therapy group, there were significant positive changes in the number of stress symptoms, intensity, mood, pain, and activity with the effect size of 0.4 to 1.1. The researchers did not observe any significant positive changes in the control group. The comparison between the groups showed that balneotherapy was superior to music therapy and no treatment group. Conclusions. Balneotherapy is beneficial for stress and fatigue reduction in comparison with music or no therapy group. Geothermal water baths have a potential as an efficient approach to diminish stress caused by working or living conditions. PMID:27051455

  15. Stress and Fatigue Management Using Balneotherapy in a Short-Time Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Lolita Rapolienė

    2016-01-01

    Full Text Available Objective. To investigate the influence of high-salinity geothermal mineral water on stress and fatigue. Method. 180 seamen were randomized into three groups: geothermal (65, music (50, and control (65. The geothermal group was administered 108 g/L salinity geothermal water bath for 2 weeks five times a week. Primary outcome was effect on stress and fatigue. Secondary outcomes were the effect on cognitive function, mood, and pain. Results. The improvements after balneotherapy were a reduction in the number and intensity of stress-related symptoms, a reduction in pain and general, physical, and mental fatigue, and an improvement in stress-related symptoms management, mood, activation, motivation, and cognitive functions with effect size from 0.8 to 2.3. In the music therapy group, there were significant positive changes in the number of stress symptoms, intensity, mood, pain, and activity with the effect size of 0.4 to 1.1. The researchers did not observe any significant positive changes in the control group. The comparison between the groups showed that balneotherapy was superior to music therapy and no treatment group. Conclusions. Balneotherapy is beneficial for stress and fatigue reduction in comparison with music or no therapy group. Geothermal water baths have a potential as an efficient approach to diminish stress caused by working or living conditions.

  16. Indications of energetic consequences of decoherence at short times for scattering from open quantum systems

    Directory of Open Access Journals (Sweden)

    C. A. Chatzidimitriou-Dreismann

    2011-06-01

    Full Text Available Decoherence of quantum entangled particles is observed in most systems, and is usually caused by system-environment interactions. Disentangling two subsystems A and B of a quantum system AB is tantamount to erasure of quantum phase relations between A and B. It is widely believed that this erasure is an innocuous process, which e.g. does not affect the energies of A and B. Surprisingly, recent theoretical investigations by different groups showed that disentangling two systems, i.e. their decoherence, can cause an increase of their energies. Applying this result to the context of neutron Compton scattering from H2 molecules, we provide for the first time experimental evidence which supports this prediction. The results reveal that the neutron-proton collision leading to the cleavage of the H-H bond in the sub-femtosecond timescale is accompanied by larger energy transfer (by about 3% than conventional theory predicts. It is proposed to interpreted the results by considering the neutron-proton collisional system as an entangled open quantum system being subject to decoherence owing to the interactions with the “environment” (i.e., two electrons plus second proton of H2.

  17. The time course of short-term hypertrophy in the absence of eccentric muscle damage.

    Science.gov (United States)

    Stock, Matt S; Mota, Jacob A; DeFranco, Ryan N; Grue, Katherine A; Jacobo, A Unique; Chung, Eunhee; Moon, Jordan R; DeFreitas, Jason M; Beck, Travis W

    2017-05-01

    It has been proposed that the increase in skeletal muscle mass observed during the initial weeks of initiating a resistance training program is concomitant with eccentric muscle damage and edema. We examined the time course of muscle hypertrophy during 4 weeks of concentric-only resistance training. Thirteen untrained men performed unilateral concentric-only dumbbell curls and shoulder presses twice per week for 4 weeks. Sets of 8-12 repetitions were performed to failure, and training loads were increased during each session. Subjects consumed 500 ml of whole milk during training. Assessments of soreness, lean mass, echo intensity, muscle thickness, relaxed and flexed arm circumference, and isokinetic strength were performed every 72 or 96 h. Soreness, echo intensity, relaxed circumference, and peak torque data did not significantly change. Significant increases in lean mass, muscle thickness, and flexed circumference were observed within seven training sessions. Lean mass was elevated at tests #7 (+109.3 g, p = .002) and #8 (+116.1 g, p = .035), with eight different subjects showing changes above the minimal difference of 139.1 g. Muscle thickness was elevated at tests #6 (+0.23 cm, p = .004), #7 (+0.31 cm, p hypertrophy may occur in the absence of eccentric muscle damage within seven training sessions.

  18. Norwegian reference values for the Short-Form Health Survey 36: development over time.

    Science.gov (United States)

    Jacobsen, Ellisiv L; Bye, Asta; Aass, Nina; Fosså, Sophie D; Grotmol, Kjersti S; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn; Hjermstad, Marianne J

    2018-05-01

    Reference values for patient-reported outcome measures are useful for interpretation of results from clinical trials. The study aims were to collect Norwegian SF-36 reference values and compare with data from 1996 to 2002. In 2015, SF-36 was sent by mail to a representative sample of the population (N = 6165). Time trends and associations between background variables and SF-36 scale scores were compared by linear regression models. The 2015 response rate was 36% (N = 2118) versus 67% (N = 2323) in 1996 and 56% (N = 5241) in 2002. Only 5% of the youngest (18-29 years) and 27% of the oldest (>70 years) responded in 2015. Age and educational level were significantly higher in 2015 relative to 1996/2002 (p 36 scores were relatively stable across surveys, controlled for background variables. In general, the most pronounced changes in 2015 were better scores on the role limitations emotional scale (7.4 points, p 70 years. Despite societal changes in Norway the past two decades, HRQoL has remained relatively stable.

  19. Energy turnaround for air pollution abatement; Energiewende dank dreckiger Luft

    Energy Technology Data Exchange (ETDEWEB)

    Ahrens, Ralph; Blume, Jutta

    2011-04-01

    In the Czech town of Lidomerice, geothermal heat and hydropower will provide clean air and stable energy rates from 2014. At the same time, the Czech government is using the National Action Plan for Renewable Energy Sources to discourage private initiatives.

  20. Inflammatory mediators in a short-time mouse model of doxorubicin-induced cardiotoxicity

    Energy Technology Data Exchange (ETDEWEB)

    Pecoraro, Michela; Del Pizzo, Mariagiovanna; Marzocco, Stefania; Sorrentino, Rosalinda [Department of Pharmacy, University of Salerno, Fisciano, SA (Italy); Ciccarelli, Michele; Iaccarino, Guido [Department of Medicine and Surgery, University of Salerno, Baronissi, SA (Italy); Pinto, Aldo [Department of Pharmacy, University of Salerno, Fisciano, SA (Italy); Popolo, Ada, E-mail: apopolo@unisa.it [Department of Pharmacy, University of Salerno, Fisciano, SA (Italy)

    2016-02-15

    Doxorubicin (DOXO) is commonly used to treat a wide range of malignant tumors, but its clinical use is limited by acute and chronic cardiotoxicity. The precise mechanism underlying DOXO-induced cardiotoxicity is still not completely elucidated, but cardiac inflammation seems to be involved. Effects of DOXO on proinflammatory cytokines, inflammatory cell infiltration, and necrosis have been proven only when a functional impairment has already occurred, so this study aimed to investigate the acute effect of DOXO administration in mouse heart. The results of our study demonstrated alterations in cardiac function parameters assessed by ultrasound within 24 h after a single injection of DOXO, with a cumulative effect along the increase of the dose and the number of DOXO administrations. At the same time, DOXO causes a significant production of proinflammatory cytokines (such as TNF-α and IL-6) with a concomitant reduction of IL-10, a well-known antiinflammatory cytokine. Furthermore, overexpression of inducible nitric oxide synthase (iNOS) in heart tissue and increased levels of serum nitrite in DOXO-treated mice were detected. Notably, DOXO administration significantly increased nitrotyrosine expression in mouse heart. Our data support the hypothesis that these early events, could be responsible for the later onset of more severe deleterious remodeling leading to DOXO induced cardiomyopathy. - Highlights: • Doxorubicin induces echocardiographic alterations of the main cardiac functional parameters. • Doxorubicin induces increase of TNF-α and IL-6 production and iNOS expression. • Doxorubicin causes a significant reduction of the antiinflammatory cytokine IL-10. • The doses are lower than that used in human. • Doxorubicin administration significantly increased nitrotyrosine expression.

  1. Short-time scale coupling between thermohaline and meteorological forcing in the Ría de Pontevedra

    Directory of Open Access Journals (Sweden)

    Paula C. Pardo

    2001-07-01

    Full Text Available Two cruises were performed in May-June and October-November 1997 in the Ría de Pontevedra under strong downwelling conditions. Temperature and salinity data were recorded in short sampling periods to describe the changes in thermohaline property distribution in a short time scale. In order to obtain the residual fluxes in the Ría, a bi-dimensional non-stationary salt and thermal-energy weight averaged box-model was applied. Outputs from this kinematic model were compared with Upwelling Index, river flow and density gradient, resulting in a good multiple correlation, which proves the strong coupling between thermohaline properties and meteorological variability. Ekman forcing affects the whole area but mainly controls the dynamics of outer zones. The intensity of its effect on the circulation pattern within the Ría depends on the grade of stratification of the water bodies. River flow is more relevant in inner parts. According to estimated spatially averaged velocities, water residence time is lower than two weeks in outer parts of the Ría, and decreases toward the inner zones.

  2. Effectiveness of Combined Tear Film Therapy in Patients with Evaporative Dry Eye with Short Tear Film Breakup Time.

    Science.gov (United States)

    Kim, Yung Hui; Kang, Yeon Soo; Lee, Hyo Seok; Choi, Won; You, In Cheon; Yoon, Kyung Chul

    2017-10-01

    The aim of this study was to evaluate the effectiveness of combined tear film therapy targeted to aqueous, mucin, and lipid layers in patients with refractory evaporative dry eye (EDE) with short tear film breakup time (TBUT). The patients who had EDE with short TBUT and severe symptoms refractory to artificial tears were treated with hyaluronic acid (HA) 0.15% and diquafosol tetrasodium (DQS) 3% (Group 1), HA and carbomer-based lipid-containing eyedrops (Liposic EDO Gel, LPO) (Group 2), or HA, DQS, and LPO (Group 3). Ocular Surface Disease Index (OSDI) score, visual analog scale (VAS) symptom score, TBUT, Schirmer score, and corneal and conjunctival staining scores were evaluated, and noninvasive tear film breakup time (NIBUT) and tear meniscus height were measured using Keratograph ® 5 M before and 1 and 3 months after treatment. OSDI scores, VAS scores, TBUT, and NIBUT were improved at 1 and 3 months after treatment in all groups (all P film layers was most effective in improving ocular symptoms and tear film quality.

  3. The use of short-echo-time 1H MRS for childhood cerebellar tumours prior to histopathological diagnosis

    International Nuclear Information System (INIS)

    Harris, Lisa M.; Peet, Andrew C.; Davies, Nigel; Natarajan, Kal; MacPherson, Lesley; Foster, Katharine; Lateef, Shaheen; Sgouros, Spyridon; Brundler, Marie-Anne; Arvanitis, Theodoros N.; Grundy, Richard G.

    2007-01-01

    Proton magnetic resonance spectroscopy (MRS) measures concentrations of metabolites in vivo and provides a powerful method for identifying tumours. MRS has not entered routine clinical use partly due to the difficulty of analysing the spectra. To create a straightforward method for interpreting short-echo-time MRS of childhood cerebellar tumours. Single-voxel MRS (1.5-T Siemens Symphony NUM4, TR/TE 1,500/30 ms) was performed at presentation in 30 children with cerebellar tumours. The MRS results were analysed for comparison with histological diagnosis. Peak heights for N-acetyl aspartate (NAA), creatine (Cr), choline (Cho) and myo-inositol (mIns) were determined and receiver operator characteristic curves used to select ratios that best discriminated between the tumour types. The method was implemented by a group of clinicians and scientists, blinded to the results. A total of 27 MRS studies met the quality control criteria. NAA/Cr >4.0 distinguished all but one of the astrocytomas from the other tumours. A combination of Cr/Cho <0.75 and mIns/NAA <2.1 separated all the medulloblastomas from the ependymomas. Peak height ratios from short-echo-time MRS can accurately predict the histopathology of childhood cerebellar tumours. (orig.)

  4. The impact of short night-time naps on performance, sleepiness and mood during a simulated night shift.

    Science.gov (United States)

    Centofanti, Stephanie A; Hilditch, Cassie J; Dorrian, Jillian; Banks, Siobhan

    2016-01-01

    Short naps on night shift are recommended in some industries. There is a paucity of evidence to verify the sustained recovery benefits of short naps in the last few hours of the night shift. Therefore, the current study aimed to investigate the sustained recovery benefits of 30 and 10-min nap opportunities during a simulated night shift. Thirty-one healthy participants (18F, 21-35 y) completed a 3-day, between-groups laboratory study with one baseline night (22:00-07:00 h time in bed), followed by one night awake (time awake from 07:00 h on day two through 10:00 h day three) with random allocation to: a 10-min nap opportunity ending at 04:00 h, a 30-min nap opportunity ending at 04:00 h or no nap (control). A neurobehavioral test bout was administered approximately every 2 h during wake periods. There were no significant differences between nap conditions for post-nap psychomotor vigilance performance after controlling for pre-nap scores (p > 0.05). The 30-min nap significantly improved subjective sleepiness compared to the 10-min nap and no-nap control (p effect.

  5. Does Occupational Exposure of Shahid Dastghieb International Airport Workers to Radiofrequency Radiation Affect Their Short Term Memory and Reaction Time?

    Directory of Open Access Journals (Sweden)

    Jarideh S.

    2015-05-01

    Full Text Available Background: Airport workers are continuously exposed to different levels of radiofrequency microwave (RF/MW radiation emitted by radar equipments. Radars are extensively used in military and aviation industries. Over the past several years, our lab has focused on the health effects of exposure to different sources of electromagnetic fields such as cellular phones, mobile base stations, mobile phone jammers, laptop computers, radars, dentistry cavitrons and MRI. The main goal of this study was to investigate if occupational exposure of Shahid Dastghieb international airport workers to radiofrequency radiation affects their short term memory and reaction time. Methods: Thirty two airport workers involved in duties at control and approach tower (21 males and 11 females, with the age range of 27-67 years old (mean age of 37.38, participated voluntary in this study. On the other hand, 29 workers (13 males, and 16 females whose offices were in the city with no exposure history to radar systems were also participated in this study as the control group. The employees’ reaction time and short term memory were analyzed using a standard visual reaction time (VRT test software and the modified Wechsler memory scale test, respectively. Results: The mean± SD values for the reaction times of the airport employees (N=32 and the control group (N=29 were 0.45±0.12 sec and 0.46±0.17 sec, respectively. Moreover, in the four subset tests; i.e. paired words, forward digit span, backward digit span and word recognition, the following points were obtained for the airport employees and the control group, respectively: (i pair words test: 28.00±13.13 and 32.07±11.65, (ii forward digit span: 8.38±1.40 and 9.03±1.32, (iii backward digit span: 5.54±1.87 and 6.31±1.46, and (iv word recognition: 5.73±2.36 and 6.50±1.93. These differences were not statistically significant. Conclusion: The occupational exposure of the employees to the RF radiation in Shahid

  6. A deep learning framework for financial time series using stacked autoencoders and long-short term memory.

    Science.gov (United States)

    Bao, Wei; Yue, Jun; Rao, Yulei

    2017-01-01

    The application of deep learning approaches to finance has received a great deal of attention from both investors and researchers. This study presents a novel deep learning framework where wavelet transforms (WT), stacked autoencoders (SAEs) and long-short term memory (LSTM) are combined for stock price forecasting. The SAEs for hierarchically extracted deep features is introduced into stock price forecasting for the first time. The deep learning framework comprises three stages. First, the stock price time series is decomposed by WT to eliminate noise. Second, SAEs is applied to generate deep high-level features for predicting the stock price. Third, high-level denoising features are fed into LSTM to forecast the next day's closing price. Six market indices and their corresponding index futures are chosen to examine the performance of the proposed model. Results show that the proposed model outperforms other similar models in both predictive accuracy and profitability performance.

  7. Shorting time of magnetically insulated reflex-ion diodes from the neutral-atom charge-exchange mechanism

    International Nuclear Information System (INIS)

    Strobel, G.

    1981-10-01

    In a magnetically insulated diode, collision-free electrons return to the cathode and no electron current is present at the anode. Electron transport to the anode is studied in this paper. Steady-state space-charge-limited flow is assumed initially. Breakdown of ion flow occurs when static neutral atoms at the anode undergo charge exchange, which results in neutral atoms drifting across the diode. These are subsequently ionized by reflexing ions producing electrons trapped in Larmor orbits throughout the diode. These electrons drift to the anode via ionization and inelastic collisions with other neutral atoms. Model calculations compare the effects of foil and mesh cathodes. Steady-state space-charge-limited ion current densities are calculated. The neutral atom density at the cathode is determined as a function of time. The shorting time of the diode is scaled versus the electrode separation d, the diode potential V 0 , the magnetic field, and the initial concentration of static neutron atoms

  8. A deep learning framework for financial time series using stacked autoencoders and long-short term memory

    Science.gov (United States)

    Bao, Wei; Rao, Yulei

    2017-01-01

    The application of deep learning approaches to finance has received a great deal of attention from both investors and researchers. This study presents a novel deep learning framework where wavelet transforms (WT), stacked autoencoders (SAEs) and long-short term memory (LSTM) are combined for stock price forecasting. The SAEs for hierarchically extracted deep features is introduced into stock price forecasting for the first time. The deep learning framework comprises three stages. First, the stock price time series is decomposed by WT to eliminate noise. Second, SAEs is applied to generate deep high-level features for predicting the stock price. Third, high-level denoising features are fed into LSTM to forecast the next day’s closing price. Six market indices and their corresponding index futures are chosen to examine the performance of the proposed model. Results show that the proposed model outperforms other similar models in both predictive accuracy and profitability performance. PMID:28708865

  9. Prediction of long time creep rupture properties of welded joints using the results of short duration creep crack incubation tests

    Energy Technology Data Exchange (ETDEWEB)

    Hosseini, E.

    2013-07-01

    This dissertation submitted to the Swiss Federal Institute of Technology ETH in Zurich examines the applicability of the LICON methodology for the prediction of long-time creep rupture strength of a dissimilar metal weld. The LICON methodology is an approach for predicting the lifetime of materials under creep loading conditions. It predicts long-time uniaxial creep strength using the results from several short duration creep crack incubation tests in conjunction with the outcome of a mechanical analysis on the test-piece. This study has re-examined the previous application of the LICON methodology for 9%Cr and 1CrMoV steels. It has shown that application of the original Lion method (based on reference stress solutions) for certain materials is not appropriate. This study therefore proposes a new development for the Lion approach which uses finite-element analysis to account for the generated multiaxial stress states within welded uniaxial test-pieces.

  10. Short-Term Forecasting of Urban Storm Water Runoff in Real-Time using Extrapolated Radar Rainfall Data

    DEFF Research Database (Denmark)

    Thorndahl, Søren Liedtke; Rasmussen, Michael R.

    2013-01-01

    Model based short-term forecasting of urban storm water runoff can be applied in realtime control of drainage systems in order to optimize system capacity during rain and minimize combined sewer overflows, improve wastewater treatment or activate alarms if local flooding is impending. A novel onl....... The radar rainfall extrapolation (nowcast) limits the lead time of the system to two hours. In this paper, the model set-up is tested on a small urban catchment for a period of 1.5 years. The 50 largest events are presented....... online system, which forecasts flows and water levels in real-time with inputs from extrapolated radar rainfall data, has been developed. The fully distributed urban drainage model includes auto-calibration using online in-sewer measurements which is seen to improve forecast skills significantly...

  11. Prediction of long time creep rupture properties of welded joints using the results of short duration creep crack incubation tests

    International Nuclear Information System (INIS)

    Hosseini, E.

    2013-01-01

    This dissertation submitted to the Swiss Federal Institute of Technology ETH in Zurich examines the applicability of the LICON methodology for the prediction of long-time creep rupture strength of a dissimilar metal weld. The LICON methodology is an approach for predicting the lifetime of materials under creep loading conditions. It predicts long-time uniaxial creep strength using the results from several short duration creep crack incubation tests in conjunction with the outcome of a mechanical analysis on the test-piece. This study has re-examined the previous application of the LICON methodology for 9%Cr and 1CrMoV steels. It has shown that application of the original Lion method (based on reference stress solutions) for certain materials is not appropriate. This study therefore proposes a new development for the Lion approach which uses finite-element analysis to account for the generated multiaxial stress states within welded uniaxial test-pieces

  12. Time-separated oscillatory fields for high-precision mass measurements on short-lived Al and Ca nuclides

    CERN Document Server

    George, Simon; Blank, B.; Blaum, K.; Breitenfeldt, M.; Hager, U.; Herfurth, F.; Herlert, A.; Kellerbauer, A.; Kluge, H.J.; Kretzschmar, M.; Lunney, D.; Savreux, R.; Schwarz, Andreas S.; Schweikhard, L.; Yazidjian, C.

    2008-01-01

    High-precision Penning trap mass measurements on the stable nuclide $^{27}$Al as well as on the short-lived radionuclides $^{26}$Al and $^{38,39}$Ca have been performed by use of radio-frequency excitation with time-separated oscillatory fields, i.e. Ramsey's method, as recently introduced for the excitation of the ion motion in a Penning trap, was applied. A comparison with the conventional method of a single continuous excitation demonstrates its advantage of up to ten times shorter measurements. The new mass values of $^{26,27}$Al clarify conflicting data in this specific mass region. In addition, the resulting mass values of the superallowed $\\beta$-emitter $^{38}$Ca as well as of the groundstate of the $\\beta$-emitter $^{26}$Al$^{m}$ confirm previous measurements and corresponding theoretical corrections of the ft-values.

  13. A deep learning framework for financial time series using stacked autoencoders and long-short term memory.

    Directory of Open Access Journals (Sweden)

    Wei Bao

    Full Text Available The application of deep learning approaches to finance has received a great deal of attention from both investors and researchers. This study presents a novel deep learning framework where wavelet transforms (WT, stacked autoencoders (SAEs and long-short term memory (LSTM are combined for stock price forecasting. The SAEs for hierarchically extracted deep features is introduced into stock price forecasting for the first time. The deep learning framework comprises three stages. First, the stock price time series is decomposed by WT to eliminate noise. Second, SAEs is applied to generate deep high-level features for predicting the stock price. Third, high-level denoising features are fed into LSTM to forecast the next day's closing price. Six market indices and their corresponding index futures are chosen to examine the performance of the proposed model. Results show that the proposed model outperforms other similar models in both predictive accuracy and profitability performance.

  14. First Isochronous Time-of-Flight Mass Measurements of Short-Lived Projectile Fragments in the ESR

    International Nuclear Information System (INIS)

    Stadlmann, J.; Geissel, H.; Hausmann, M.; Nolden, F.; Radon, T.; Schatz, H.; Scheidenberger, C.; Attallah, F.; Beckert, K.; Bosch, F.; Falch, M.; Franczak, B.; Franzke, B.; Kerscher, Th.; Klepper, O.; Kluge, H.J.; Kozhuharov, C.; Loebner, K.E.G.; Muenzenberg, G.; Novikov, Yu.N.; Steck, M.; Sun, Z.; Suemmerer, K.; Weick, H.; Wollnik, H.

    2000-01-01

    A new method for precise mass measurements of short-lived hot nuclei is presented. These nuclei were produced via projectile fragmentation, separated with the FRS and injected into the storage ring ESR being operated in the isochronous mode. The revolution time of the ions is measured with a time-of-flight detector sensitive to single particles. This new method allows access to exotic nuclei with half-lives in the microsecond region. First results from this novel method obtained with measurements on neutron-deficient fragments of a chromium primary beam with half-lives down to 50 ms are reported. A precision of deltam/m ≤ 5 · 10 -6 has been achieved

  15. Using corporate finance to engineer an organizational turnaround.

    Science.gov (United States)

    Sussman, Jason H; Dziesinski, Ray R

    2002-11-01

    Georgia's Southern Regional Medical Center used a proven corporate finance approach to dramatically improve its financial position and integrate its strategic and financial planning. Managers throughout the organization were educated about principles of corporate finance. Reliable cash-flow projections were used to create a multiyear glide path to financial stability. Initiatives were tied to specific time frames and quantifiable financial goals and underwent a standardized review process.

  16. Time-dependent H-like and He-like Al lines produced by ultra-short pulse laser

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Takako; Kato, Masatoshi [National Inst. for Fusion Science, Nagoya (Japan); Shepherd, R; Young, B; More, R; Osterheld, Al

    1998-03-01

    We have performed numerical modeling of time-resolved x-ray spectra from thin foil targets heated by the LLNL Ultra-short pulse (USP) laser. The targets were aluminum foils of thickness ranging from 250 A to 1250 A, heated with 120 fsec pulses of 400 nm light from the USP laser. The laser energy was approximately 0.2 Joules, focused to a 3 micron spot size for a peak intensity near 2 x 10{sup 19} W/cm{sup 2}. Ly{alpha} and He{alpha} lines were recorded using a 900 fsec x-ray streak camera. We calculate the effective ionization, recombination and emission rate coefficients including density effects for H-like and He-like aluminum ions using a collisional radiative model. We calculate time-dependent ion abundances using these effective ionization and recombination rate coefficients. The time-dependent electron temperature and density used in the calculation are based on an analytical model for the hydrodynamic expansion of the target foils. During the laser pulse the target is ionized. After the laser heating stops, the plasma begins to recombine. Using the calculated time dependent ion abundances and the effective emission rate coefficients, we calculate the time dependent Ly{alpha} and He{alpha} lines. The calculations reproduce the main qualitative features of the experimental spectra. (author)

  17. Short communication

    African Journals Online (AJOL)

    abp

    2017-09-04

    Sep 4, 2017 ... Face-to-face interviews were conducted using a standardized ... Short communication. Open Access ... clinic during the time of the study and were invited to participate in the study. .... consume them. This is another ...

  18. Non-linear dynamical classification of short time series of the rössler system in high noise regimes.

    Science.gov (United States)

    Lainscsek, Claudia; Weyhenmeyer, Jonathan; Hernandez, Manuel E; Poizner, Howard; Sejnowski, Terrence J

    2013-01-01

    Time series analysis with delay differential equations (DDEs) reveals non-linear properties of the underlying dynamical system and can serve as a non-linear time-domain classification tool. Here global DDE models were used to analyze short segments of simulated time series from a known dynamical system, the Rössler system, in high noise regimes. In a companion paper, we apply the DDE model developed here to classify short segments of encephalographic (EEG) data recorded from patients with Parkinson's disease and healthy subjects. Nine simulated subjects in each of two distinct classes were generated by varying the bifurcation parameter b and keeping the other two parameters (a and c) of the Rössler system fixed. All choices of b were in the chaotic parameter range. We diluted the simulated data using white noise ranging from 10 to -30 dB signal-to-noise ratios (SNR). Structure selection was supervised by selecting the number of terms, delays, and order of non-linearity of the model DDE model that best linearly separated the two classes of data. The distances d from the linear dividing hyperplane was then used to assess the classification performance by computing the area A' under the ROC curve. The selected model was tested on untrained data using repeated random sub-sampling validation. DDEs were able to accurately distinguish the two dynamical conditions, and moreover, to quantify the changes in the dynamics. There was a significant correlation between the dynamical bifurcation parameter b of the simulated data and the classification parameter d from our analysis. This correlation still held for new simulated subjects with new dynamical parameters selected from each of the two dynamical regimes. Furthermore, the correlation was robust to added noise, being significant even when the noise was greater than the signal. We conclude that DDE models may be used as a generalizable and reliable classification tool for even small segments of noisy data.

  19. Sistem kontrol inventori pemasokan barang Secara Real Time Menggunakan Vendor-Managed Inventory (VMI dan Short Message Service (SMS

    Directory of Open Access Journals (Sweden)

    Rinaldo Turang

    2016-01-01

    Full Text Available This research underlines the urgency of real-time stock replenishment control system for distributors using vendor-managed inventory. It is valuable in improving corporate performance in lowering inventory cost as well as making better customer service due to the cut made in ordering cycle. The system produces real-time information on stock available at the retailing stores. Stock replenishment can then be done by the distributor at the right time. Using Short Message Service (SMS as a one-way information channel from retailers to their distributor, the data of every transaction of the supervised item are processed by a rule-based forward-chaining inference system to determine the item’s availability in stores. Folowing steps in Rapid Application Development (RAD, the construction of this system takes place through business modeling, data modeling, process modeling of VMI system, then the application is generated and tested as a prototype. The results are: the stock replenishment control system are able to make transactional data at the stores transparent to the distributor, facilitating the continuation in stock delivery. System architecture reduces the time needed to access information about sales on supervised item by using SMS shortcut. This control system developed in stores can be operationally independent from the retailing systems. Rule-based forward-chaining inference technique processes facts on stock variations, resulting in stock replenishment notification such as normal, reserve, and depleted warning. Keywords: VMI, inventory; Stock replenishment; Rule-based reasoning; Forward-chaining system, RAD

  20. Field demonstration of rapid turnaround, multilevel groundwater screening

    International Nuclear Information System (INIS)

    Tingle, A.R.; Baker, L.; Long, D.D.

    1994-01-01

    A combined technology approach to rapidly characterizing source area and downgradient groundwater associated with a past fuel spill has been field tested. The purpose of this investigation was to determine the presence and extent of fuel-related compounds or indications of their biodegradation in groundwater. The distance from the source area to be investigated was established by calculating the potential extent of a plume based only on groundwater flow velocities. To accomplish this objective, commercially available technologies were combined and used to rapidly assess the source area and downgradient groundwater associated with the fuel discharge. The source of contamination that was investigated overlies glacial sand and gravel outwash deposits. Historical data suggest that from 1955 to 1970 as many as 1 to 6 million pi of aviation gasoline (AVGAS) were god at the study area. Although the remedial investigation (RI) for this study area indicated fuel-related groundwater contamination at the source area, fuel-related contamination was not detected in downgradient monitoring wells. Rapid horizontal groundwater velocities and the 24-year time span from the last reported spill farther suggest that a plume of contaminated groundwater could extend several thousand feet downgradient. The lack of contamination downgradient from the source suggests two possibilities: (1) monitoring wells installed during the RI did not intersect the plume or (2) fuel-related compounds had naturally degraded

  1. Process Improvement Tools, Commitment to Change Lead to Serious Turnaround.

    Science.gov (United States)

    Birznieks, Derek; Zane, Richard

    2017-05-01

    The ED at the University of Colorado Hospital (UCH) has undergone a dramatic transformation in recent years, doubling in size while also using process improvement methods to dramatically reduce wait times, eliminate ambulance diversion, and boost patient satisfaction. Throughout this period, volume has continued to increase while the cost per patient and avoidable hospital admissions have experienced steady declines. Guiding the effort has been a series of core principles, with a particular focus on making sure that all processes are patient-centered. . To begin the improvement effort, ED leaders established a leadership team, and hired a process improvement chief with no previous experience in healthcare to provide fresh, outside perspective on processes. . In addition to mandating that all processes be patient-centered, the other guiding principles included a commitment to use and track data, to speak with one voice, to value everyone's perspective, to deliver high-quality care to all patients, and to set a standard for other academic medical centers. . To get points on the board early and win approval from staff, one of the first changes administrators implemented was to hire scribes for every physician so they wouldn't be bogged down with data input. The approach has essentially paid for itself. . Among the biggest changes was the elimination of triage, a process that improvement teams found no longer added value or quality to the patient experience. . Leadership also has moved to equilibrate the size and staff of the various zones in the ED so that they are more generic and less specialized. The move has facilitated patient flow, enabling patients in zones with resuscitation bays to connect with providers quickly.

  2. Effect of high-temperature, short-time (HTST) pasteurization on milk containing low numbers of Mycobacterium paratuberculosis.

    Science.gov (United States)

    Grant, I R; Ball, H J; Rowe, M T

    1998-02-01

    The efficacy of high-temperature, short-time (HTST) pasteurization (72 degrees C/15 s) when low numbers (HTST pasteurization using laboratory pasteurizing units. Ten bovine strains of Myco. paratuberculosis were tested in triplicate. Culture in BACTEC Middlebrook 12B radiometric medium detected acid-fast survivors in 14.8% and 10% of HTST-pasteurized milk samples at the 10(3) and 10(2) cfu ml-1 inoculum levels, respectively, whereas conventional culture on Herrold's egg yolk medium containing mycobactin J detected acid-fast survivors in only 3.7% and 6.7% of the same milk samples. IS900-based PCR confirmed that these acid-fast survivors were Myco. paratuberculosis. No viable Myco. paratuberculosis were isolated from HTST-pasteurized milk initially containing either 10 cfu ml-1 or 10 cfu 50 ml-1.

  3. Short-time fourth-order squeezing effects in spontaneous and stimulated four- and six-wave mixing processes

    International Nuclear Information System (INIS)

    Giri, Dilip Kumar; Gupta, P S

    2003-01-01

    The concept of fourth-order squeezing of the electromagnetic field is investigated in the fundamental mode in spontaneous and stimulated four- and six-wave mixing processes under the short-time approximation based on a fully quantum mechanical approach. The coupled Heisenberg equations of motion involving real and imaginary parts of the quadrature operators are established. The possibility of obtaining fourth-order squeezing is studied. The dependence of fourth-order squeezing on the number of photons is also investigated. It is shown that fourth-order squeezing, which is a higher-order squeezing, allows a much larger fractional noise reduction than lower-order squeezing. It is shown that squeezing is greater in a stimulated process than the corresponding squeezing in spontaneous interaction. The conditions for obtaining maximum and minimum squeezing are obtained. We have also established the non-classical nature of squeezed radiation using the Glauber-Sudarshan representation

  4. Analyses of kinetic glass transition in short-range attractive colloids based on time-convolutionless mode-coupling theory.

    Science.gov (United States)

    Narumi, Takayuki; Tokuyama, Michio

    2017-03-01

    For short-range attractive colloids, the phase diagram of the kinetic glass transition is studied by time-convolutionless mode-coupling theory (TMCT). Using numerical calculations, TMCT is shown to recover all the remarkable features predicted by the mode-coupling theory for attractive colloids: the glass-liquid-glass reentrant, the glass-glass transition, and the higher-order singularities. It is also demonstrated through the comparisons with the results of molecular dynamics for the binary attractive colloids that TMCT improves the critical values of the volume fraction. In addition, a schematic model of three control parameters is investigated analytically. It is thus confirmed that TMCT can describe the glass-glass transition and higher-order singularities even in such a schematic model.

  5. A voxel-based investigation for MRI-only radiotherapy of the brain using ultra short echo times

    DEFF Research Database (Denmark)

    Edmund, Jens Morgenthaler; Kjer, Hans Martin; Van Leemput, Koen

    2014-01-01

    including or excluding additional spatial information. Approach 3 used a statistical regression correlating MRI voxels with their corresponding CT voxels. A similar photon and proton treatment plan was generated for a target positioned between the nasal cavity and the brainstem for all patients. The CT...... receiving cranial irradiation, each containing a co-registered MRI and CT scan, were included. An ultra short echo time MRI sequence for bone visualization was used. Six methods were investigated for three popular types of voxel-based approaches; (1) threshold-based segmentation, (2) Bayesian segmentation...... significantly better than the threshold and Bayesian segmentation methods (excluding spatial information). All methods agreed significantly better with CT than a reference water MRI comparison. The mean dosimetric deviation for photons and protons compared to the CT was about 2% and highest in the gradient dose...

  6. Implementing high-temperature short-time media treatment in commercial-scale cell culture manufacturing processes.

    Science.gov (United States)

    Pohlscheidt, Michael; Charaniya, Salim; Kulenovic, Fikret; Corrales, Mahalia; Shiratori, Masaru; Bourret, Justin; Meier, Steven; Fallon, Eric; Kiss, Robert

    2014-04-01

    The production of therapeutic proteins by mammalian cell culture is complex and sets high requirements for process, facility, and equipment design, as well as rigorous regulatory and quality standards. One particular point of concern and significant risk to supply chain is the susceptibility to contamination such as bacteria, fungi, mycoplasma, and viruses. Several technologies have been developed to create barriers for these agents to enter the process, e.g. filtration, UV inactivation, and temperature inactivation. However, if not implemented during development of the manufacturing process, these types of process changes can have significant impact on process performance if not managed appropriately. This article describes the implementation of the high-temperature short-time (HTST) treatment of cell culture media as an additional safety barrier against adventitious agents during the transfer of a large-scale commercial cell culture manufacturing process. The necessary steps and experiments, as well as subsequent results during qualification runs and routine manufacturing, are shown.

  7. Improving Thin Bed Identification in Sarawak Basin Field using Short Time Fourier Transform Half Cepstrum (STFTHC) method

    Science.gov (United States)

    Nizarul, O.; Hermana, M.; Bashir, Y.; Ghosh, D. P.

    2016-02-01

    In delineating complex subsurface geological feature, broad band of frequencies are needed to unveil the often hidden features of hydrocarbon basin such as thin bedding. The ability to resolve thin geological horizon on seismic data is recognized to be a fundamental importance for hydrocarbon exploration, seismic interpretation and reserve prediction. For thin bedding, high frequency content is needed to enable tuning, which can be done by applying the band width extension technique. This paper shows an application of Short Time Fourier Transform Half Cepstrum (STFTHC) method, a frequency bandwidth expansion technique for non-stationary seismic signal in increasing the temporal resolution to uncover thin beds and improve characterization of the basin. A wedge model and synthetic seismic data is used to quantify the algorithm as well as real data from Sarawak basin were used to show the effectiveness of this method in enhancing the resolution.

  8. Fetal short time variation during labor: a non-invasive alternative to fetal scalp pH measurements?

    Science.gov (United States)

    Schiermeier, Sven; Reinhard, Joscha; Hatzmann, Hendrike; Zimmermann, Ralf C; Westhof, Gregor

    2009-01-01

    To determine whether short time variation (STV) of fetal heart beat correlates with scalp pH measurements during labor. From 1279 deliveries, 197 women had at least one fetal scalp pH measurement. Using the CTG-Player, STVs were calculated from the electronically saved cardiotocography (CTG) traces and related to the fetal scalp pH measurements. There was no correlation between STV and fetal scalp pH measurements (r=-0.0592). Fetal STV is an important parameter with high sensitivity for antenatal fetal acidosis. This study shows that STV calculations do not correlate with fetal scalp pH measurements during labor, hence are not helpful in identifying fetal acidosis.

  9. Experience from transportation of irradiated WWER-440 fuel assemblies at Kozloduy NPP site after a short cooling time

    International Nuclear Information System (INIS)

    Stoyanova, I.; Kamenov, A.; Byrzev, L.; Christoskov, I.

    2003-01-01

    The presented results from the computation and analysis of the radiation characteristics of the irradiated fuel assemblies by the date of their transportation according to the selected loading patterns of the VSPOT cask and following the modified technology of transportation, i.e. without replacement of the pool solution by pure condensate, as well as the corresponding experimental results, confirm the applicability of the newly introduced safety criterion for the selection of a loading pattern of the cask with irradiated fuel assemblies after a short cooling time. The comparison between measured and computed surface dose rates shows that during the procedure of transfer of irradiated fuel assemblies from the pools of Units 1 and 2 to the pools of Kozloduy NPP Units 3 and 4 all safety limits, incl. the radiation protection requirements, were met

  10. A Distributed Web-based Solution for Ionospheric Model Real-time Management, Monitoring, and Short-term Prediction

    Science.gov (United States)

    Kulchitsky, A.; Maurits, S.; Watkins, B.

    2006-12-01

    provide inputs for the next ionospheic model time step and then stored in a MySQL database as the first part of the time-specific record. The RMM then performs synchronization of the input times with the current model time, prepares a decision on initialization for the next model time step, and monitors its execution. Then, as soon as the model completes computations for the next time step, RMM visualizes the current model output into various short-term (about 1-2 hours) forecasting products and compares prior results with available ionospheric measurements. The RMM places prepared images into the MySQL database, which can be located on a different computer node, and then proceeds to the next time interval continuing the time-loop. The upper-level interface of this real-time system is the a PHP-based Web site (http://www.arsc.edu/SpaceWeather/new). This site provides general information about the Earth polar and adjacent mid-latitude ionosphere, allows for monitoring of the current developments and short-term forecasts, and facilitates access to the comparisons archive stored in the database.

  11. 26 CFR 1.6074-2 - Time for filing declarations by corporations in case of a short taxable year.

    Science.gov (United States)

    2010-04-01

    ...(a) are met before the 1st day of the 9th month of the short taxable year, the declaration shall be filed on or before the 15th day of the 9th month of such short year. In the case of a short taxable year...) Example. The application of the provisions of this paragraph may be illustrated by the following example...

  12. Positive Pacing Strategies Are Utilized by Elite Male and Female Para-cyclists in Short Time Trials in the Velodrome.

    Science.gov (United States)

    Wright, Rachel L

    2015-01-01

    In para-cycling, competitors are classed based on functional impairment resulting in cyclists with neurological and locomotor impairments competing against each other. In Paralympic competition, classes are combined by using a factoring adjustment to race times to produce the overall medallists. Pacing in short-duration track cycling events is proposed to utilize an "all-out" strategy in able-bodied competition. However, pacing in para-cycling may vary depending on the level of impairment. Analysis of the pacing strategies employed by different classification groups may offer scope for optimal performance; therefore, this study investigated the pacing strategy adopted during the 1-km time trial (TT) and 500-m TT in elite C1 to C3 para-cyclists and able-bodied cyclists. Total times and intermediate split times (125-m intervals; measured to 0.001 s) were obtained from the C1-C3 men's 1-km TT (n = 28) and women's 500-m TT (n = 9) from the 2012 Paralympic Games and the men's 1-km TT (n = 19) and women's 500-m TT (n = 12) from the 2013 UCI World Track Championships from publically available video. Split times were expressed as actual time, factored time (for the para-cyclists) and as a percentage of total time. A two-way analysis of variance was used to investigate differences in split times between the different classifications and the able-bodied cyclists in the men's 1-km TT and between the para-cyclists and able-bodied cyclists in the women's 500-m TT. The importance of position at the first split was investigated with Kendall's Tau-b correlation. The first 125-m split time was the slowest for all cyclists, representing the acceleration phase from a standing start. C2 cyclists were slowest at this 125-m split, probably due to a combination of remaining seated in this acceleration phase and a high proportion of cyclists in this group being trans-femoral amputees. Not all cyclists used aero-bars, preferring to use drop, flat or bullhorn handlebars. Split times

  13. Positive pacing strategies are utilised by elite male and female para-cyclists in short time trials in the velodrome

    Directory of Open Access Journals (Sweden)

    Rachel Lindsey Wright

    2016-01-01

    Full Text Available In para-cycling, competitors are classed based on functional impairment resulting in cyclists with neurological and locomotor impairments competing against each other. In Paralympic competition, classes are combined by using a factoring adjustment to race times to produce the overall medallists. Pacing in short-duration track cycling events is proposed to utilise an all-out strategy in able-bodied competition. However, pacing in para-cycling may vary depending on the level of impairment. Analysis of the pacing strategies employed by different classification groups may offer scope for optimal performance; therefore, this study investigated the pacing strategy adopted during the 1-km time trial (TT and 500-m TT in elite C1 to C3 para-cyclists and able-bodied cyclists. Total times and intermediate split times (125-m intervals; measured to 0.001s were obtained from the C1-C3 men’s 1-km TT (n=28 and women’s 500-m TT (n=9 from the 2012 Paralympic Games and the men’s 1-km TT (n=19 and women’s 500-m TT (n=12 from the 2013 UCI World Track Championships from publically available video. Split times were expressed as actual time, factored time (for the para-cyclists and as a percentage of total time. A two-way analysis of variance was used to investigate differences in split times between the different classifications and the able-bodied cyclists in the men’s 1-km TT and between the para-cyclists and able-bodied cyclists in the women’s 500-m TT. The importance of position at the first split was investigated with Kendall’s Tau-b correlation. The first 125-m split time was the slowest for all cyclists, representing the acceleration phase from a standing start. C2 cyclists were slowest at this 125-m split, probably due to a combination of remaining seated in this acceleration phase and a high proportion of cyclists in this group being trans-femoral amputees. Not all cyclists used aero-bars, preferring to use drop, flat or bullhorn handlebars

  14. Short time-scale optical variability properties of the largest AGN sample observed with Kepler/K2

    Science.gov (United States)

    Aranzana, E.; Körding, E.; Uttley, P.; Scaringi, S.; Bloemen, S.

    2018-05-01

    We present the first short time-scale (˜hours to days) optical variability study of a large sample of active galactic nuclei (AGNs) observed with the Kepler/K2 mission. The sample contains 252 AGN observed over four campaigns with ˜30 min cadence selected from the Million Quasar Catalogue with R magnitude <19. We performed time series analysis to determine their variability properties by means of the power spectral densities (PSDs) and applied Monte Carlo techniques to find the best model parameters that fit the observed power spectra. A power-law model is sufficient to describe all the PSDs of our sample. A variety of power-law slopes were found indicating that there is not a universal slope for all AGNs. We find that the rest-frame amplitude variability in the frequency range of 6 × 10-6-10-4 Hz varies from 1to10 per cent with an average of 1.7 per cent. We explore correlations between the variability amplitude and key parameters of the AGN, finding a significant correlation of rest-frame short-term variability amplitude with redshift. We attribute this effect to the known `bluer when brighter' variability of quasars combined with the fixed bandpass of Kepler data. This study also enables us to distinguish between Seyferts and blazars and confirm AGN candidates. For our study, we have compared results obtained from light curves extracted using different aperture sizes and with and without detrending. We find that limited detrending of the optimal photometric precision light curve is the best approach, although some systematic effects still remain present.

  15. The short-term effects of air pollutants on respiratory disease mortality in Wuhan, China: comparison of time-series and case-crossover analyses

    OpenAIRE

    Meng Ren; Na Li; Zhan Wang; Yisi Liu; Xi Chen; Yuanyuan Chu; Xiangyu Li; Zhongmin Zhu; Liqiao Tian; Hao Xiang

    2017-01-01

    Few studies have compared different methods when exploring the short-term effects of air pollutants on respiratory disease mortality in Wuhan, China. This study assesses the association between air pollutants and respiratory disease mortality with both time-series and time-stratified?case-crossover designs. The generalized additive model (GAM) and the conditional logistic regression model were used to assess the short-term effects of air pollutants on respiratory disease mortality. Stratified...

  16. Short-Term Interferential Transabdominal Electrical Stimulation Did Not Change Oral-Rectal Transit Time in Piglets.

    Science.gov (United States)

    Tan, Andre Y F; Sourial, Magdy; Hutson, John M; Southwell, Bridget R

    2018-03-02

    Transcutaneous electrical stimulation (TES) using interferential current (IFC) is a new therapeutic treatment for constipation. Clinical studies show that TES-IFC for 3-6 months improves colonic transit, but it is not clear if short-term stimulation affects transit or the effect requires longer to develop. The aim of this study was to determine if TES-IFC for only four days affects oral-rectal transit time in healthy pigs. Twenty-two 4-5-week old large white female piglets had transit studies during week 4 and week 5 by placing a capsule containing 18 radiopaque plastic markers in the esophagus under anesthetic followed by x-rays at 6, 30, 54, and 78 hours. Animals were randomly assigned to active or control groups. The active group received TES for 30 min daily for four days. Interferential current was applied through four electrodes (4 × 4 cm), with two para-spinal just below the last rib and two on the belly at the same level. Stimulation was at 4000 Hz and 4080-4160 Hz with currents crossing through the abdominal cavity. Whole bowel transit times ranged from 7.7 to 72.2 hours, stomach transit from transit time from 5 to 53 hours. Transit times were the same for the control (median 28.4 hours) and TES-IFC (23.0 hours) groups in the prestimulation and stimulation weeks (control 23.0, TES-IFC 19.8 hours) with no change within or between groups. Four days of half-hour TES-IFC daily in healthy 5-week-old piglets did not change oral-rectal transit time. © 2018 International Neuromodulation Society.

  17. Double peak-induced distance error in short-time-Fourier-transform-Brillouin optical time domain reflectometers event detection and the recovery method.

    Science.gov (United States)

    Yu, Yifei; Luo, Linqing; Li, Bo; Guo, Linfeng; Yan, Jize; Soga, Kenichi

    2015-10-01

    The measured distance error caused by double peaks in the BOTDRs (Brillouin optical time domain reflectometers) system is a kind of Brillouin scattering spectrum (BSS) deformation, discussed and simulated for the first time in the paper, to the best of the authors' knowledge. Double peak, as a kind of Brillouin spectrum deformation, is important in the enhancement of spatial resolution, measurement accuracy, and crack detection. Due to the variances of the peak powers of the BSS along the fiber, the measured starting point of a step-shape frequency transition region is shifted and results in distance errors. Zero-padded short-time-Fourier-transform (STFT) can restore the transition-induced double peaks in the asymmetric and deformed BSS, thus offering more accurate and quicker measurements than the conventional Lorentz-fitting method. The recovering method based on the double-peak detection and corresponding BSS deformation can be applied to calculate the real starting point, which can improve the distance accuracy of the STFT-based BOTDR system.

  18. Worldwide CO2 emissions 2014. Shimmer of hope to turnaround reinforce - but no all-clear signal

    International Nuclear Information System (INIS)

    Ziesing, Hans-Joachim

    2015-01-01

    In 2014, global CO 2 emissions increase according to initial calculations by 0.5%. Apart from the two crisis years 2008/2009 was the weakest increase since the beginning of the century. As a result, CO 2 emissions reached about 32.6 billion tonnes a new climax. A turnaround this is not yet, but the CO 2 emissions in many countries, particularly in industrialized countries declined. Thus, the CO 2 emissions have declined in the Annex I countries overall by 1.8%. For this particular contributed the development in the EU, in almost without exception, all Member States have experienced an emission reduction. Of the major countries, this also applies to the Ukraine, Japan, Russia and Australia. In contrast, there was an increase in the US, although this turned out very moderate with an increase of just under 1%. If the global CO 2 emissions have increased despite the decline in the group of Annex I countries again, this is primarily a result of the increase in developing countries. Here, CO 2 emissions were by around the year 2014 415 million tons or 2.4% higher than 2013. Since 2008, China occupied top position ahead of the US in 2014 was not expanded because for many years here was the increase for the first time below 1%. By contrast, CO 2 emissions increased significantly in India by approx. 8% and in Brazil as in the Middle East by about 4%. [de

  19. Evaluating Operating Room Turnaround Times and Cancellations at Dwight D. Eisenhower Army Medical Center

    National Research Council Canada - National Science Library

    Amsink, William L

    2005-01-01

    .... This study describes the inefficient use of the current operating room management software system, and identifies strategies to improve operating room efficiency by analyzing the most common causes...

  20. Evaluation of short repetition time, partial flip angle, gradient recalled echo pulse sequences in cervical spine imaging

    International Nuclear Information System (INIS)

    Enzmann, D.; Rubin, J.B.

    1987-01-01

    A short repetition time (TR), partial flip angle, gradient recalled echo pulse sequence (GRASS) was prospectively studied to optimize it for the diagnosis of cervical disk and cord disease in 98 patients. Changes in signal-to-noise ratio (SNR) and contrast were measured as the following parameters were varied: flip angle (3 0 to 18 0 ), TR (22-60 msec), and echo time (TE) (12.5-25 msec). Flip angle was the single most important parameter. For disk disease, cerebrospinal fluid (CSF) SNR peaked at an 8 0 flip angle in the axial view but at a 4 0 flip angle in the sagittal view. In the sagittal view, disk-CSF contrast decreased progressively from a flip angle of 3 0 , while in the axial view it peaked at 10 0 . For cord lesions the findings were similar except that lesion-cord contrast could be increased by lengthening both TR and TE. No one combination of parameters proved greatly superior for either disk disease or cord disease. The selection of parameters required balancing of several factors that often had opposing effects

  1. A probabilistic method for the estimation of ocean surface currents from short time series of HF radar data

    Science.gov (United States)

    Guérin, Charles-Antoine; Grilli, Stéphan T.

    2018-01-01

    We present a new method for inverting ocean surface currents from beam-forming HF radar data. In contrast with the classical method, which inverts radial currents based on shifts of the main Bragg line in the radar Doppler spectrum, the method works in the temporal domain and inverts currents from the amplitude modulation of the I and Q radar time series. Based on this principle, we propose a Maximum Likelihood approach, which can be combined with a Bayesian inference method assuming a prior current distribution, to infer values of the radial surface currents. We assess the method performance by using synthetic radar signal as well as field data, and systematically comparing results with those of the Doppler method. The new method is found advantageous for its robustness to noise at long range, its ability to accommodate shorter time series, and the possibility to use a priori information to improve the estimates. Limitations are related to current sign errors at far-ranges and biased estimates for small current values and very short samples. We apply the new technique to a data set from a typical 13.5 MHz WERA radar, acquired off of Vancouver Island, BC, and show that it can potentially improve standard synoptic current mapping.

  2. A Bayesian method for characterizing distributed micro-releases: II. inference under model uncertainty with short time-series data.

    Energy Technology Data Exchange (ETDEWEB)

    Marzouk, Youssef; Fast P. (Lawrence Livermore National Laboratory, Livermore, CA); Kraus, M. (Peterson AFB, CO); Ray, J. P.

    2006-01-01

    Terrorist attacks using an aerosolized pathogen preparation have gained credibility as a national security concern after the anthrax attacks of 2001. The ability to characterize such attacks, i.e., to estimate the number of people infected, the time of infection, and the average dose received, is important when planning a medical response. We address this question of characterization by formulating a Bayesian inverse problem predicated on a short time-series of diagnosed patients exhibiting symptoms. To be of relevance to response planning, we limit ourselves to 3-5 days of data. In tests performed with anthrax as the pathogen, we find that these data are usually sufficient, especially if the model of the outbreak used in the inverse problem is an accurate one. In some cases the scarcity of data may initially support outbreak characterizations at odds with the true one, but with sufficient data the correct inferences are recovered; in other words, the inverse problem posed and its solution methodology are consistent. We also explore the effect of model error-situations for which the model used in the inverse problem is only a partially accurate representation of the outbreak; here, the model predictions and the observations differ by more than a random noise. We find that while there is a consistent discrepancy between the inferred and the true characterizations, they are also close enough to be of relevance when planning a response.

  3. Nucleoside uptake in macrophages from various murine strains: a short-time and a two-step stimulation model

    International Nuclear Information System (INIS)

    Busolo, F.; Conventi, L.; Grigolon, M.; Palu, G.

    1991-01-01

    Kinetics of [3H]-uridine uptake by murine peritoneal macrophages (pM phi) is early altered after exposure to a variety of stimuli. Alterations caused by Candida albicans, lipopolysaccharide (LPS) and recombinant interferon-gamma (rIFN-gamma) were similar in SAVO, C57BL/6, C3H/HeN and C3H/HeJ mice, and were not correlated with an activation process as shown by the amount of tumor necrosis factor-alpha (TNF-alpha) being released. Short-time exposure to all stimuli resulted in an increased nucleoside uptake by SAVO pM phi, suggesting that the tumoricidal function of this cell either depends from the type of stimulus or the time when the specific interaction with the cell receptor is taking place. Experiments with priming and triggering signals confirmed the above findings, indicating that the increase or the decrease of nucleoside uptake into the cell depends essentially on the chemical nature of the priming stimulus. The triggering stimulus, on the other hand, is only able to amplify the primary response

  4. Analysis of lightning fault detection, location and protection on short and long transmission lines using Real Time Digital Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Andre Luiz Pereira de [Siemens Ltda., Sao Paulo, SP (Brazil)], E-mail: andreluiz.oliveira@siemens.com

    2007-07-01

    The purpose of this paper is to present an analysis of lightning fault detection, location and protection using numeric distance relays applied in high voltage transmission lines, more specifically in the 500 kV transmission lines of CEMIG (Brazilian Energy Utility) between the Vespasiano 2 - Neves 1 (short line - 23.9 km) and Vespasiano 2 - Mesquita (long line - 148.6 km) substations. The analysis was based on the simulations results of numeric distance protective relays on power transmission lines, realized in September 02 to 06, 2002, at Siemens AG's facilities (Erlangen - Germany), using Real Time Digital Simulator (RTDS{sup TM}). Several lightning faults simulations were accomplished, in several conditions of the electrical power system where the protective relays would be installed. The results are presented not only with the times of lightning faults elimination, but also all the functionality of a protection system, including the correct detection, location and other advantages that these modern protection devices make possible to the power system. (author)

  5. Anatomy of a public health agency turnaround: the case of the general health district in Mahoning County.

    Science.gov (United States)

    Honoré, Peggy A; Stefanak, Matthew; Dessens, Scott

    2012-01-01

    A turnaround describes an organization's ability to recover from successive periods of decline. Current and projected declines in US economic conditions continue to place local public health departments at risk of fiscal exigency. This examination focused on turnaround methodologies used by a local public health department to reverse successive periods of operational and financial declines. Illustrations are provided on the value added by implementing financial ratio and trend analysis in addition to using evidence-based private sector turnaround strategies of retrenchment, repositioning, and reorganization. Evidence has shown how the financial analysis and strategies aided in identifying operational weakness and set in motion corrective measures. The Public Health Uniform Data System is introduced along with a list of standards offered for mainstreaming these and other routine stewardship practices to diagnose, predict, and prevent agency declines.

  6. Modelling the short term interest with stochastic differential equation in continuous time: linear versus non-linear mode

    OpenAIRE

    2014-01-01

    M.Com. (Financial Economics) Recently, there has been a growth in the bond market. This growth has brought with it an ever-increasing volume and range of interest rate depended derivative products known as interest rate derivatives. Amongst the variables used in pricing these derivative products is the short-term interest rate. A numbers of short-term interest rate models that are used to fit the short-term interest rate exist. Therefore, understanding the features characterised by various...

  7. Finite-size effects in the short-time height distribution of the Kardar-Parisi-Zhang equation

    Science.gov (United States)

    Smith, Naftali R.; Meerson, Baruch; Sasorov, Pavel

    2018-02-01

    We use the optimal fluctuation method to evaluate the short-time probability distribution P(H, L, t) of height at a single point, H=h(x=0, t) , of the evolving Kardar-Parisi-Zhang (KPZ) interface h(x, t) on a ring of length 2L. The process starts from a flat interface. At short times typical (small) height fluctuations are unaffected by the KPZ nonlinearity and belong to the Edwards-Wilkinson universality class. The nonlinearity, however, strongly affects the (asymmetric) tails of P(H) . At large L/\\sqrt{t} the faster-decaying tail has a double structure: it is L-independent, -\\lnP˜≤ft\\vert H\\right\\vert 5/2/t1/2 , at intermediately large \\vert H\\vert , and L-dependent, -\\lnP˜ ≤ft\\vert H\\right\\vert 2L/t , at very large \\vert H\\vert . The transition between these two regimes is sharp and, in the large L/\\sqrt{t} limit, behaves as a fractional-order phase transition. The transition point H=Hc+ depends on L/\\sqrt{t} . At small L/\\sqrt{t} , the double structure of the faster tail disappears, and only the very large-H tail, -\\lnP˜ ≤ft\\vert H\\right\\vert 2L/t , is observed. The slower-decaying tail does not show any L-dependence at large L/\\sqrt{t} , where it coincides with the slower tail of the GOE Tracy-Widom distribution. At small L/\\sqrt{t} this tail also has a double structure. The transition between the two regimes occurs at a value of height H=Hc- which depends on L/\\sqrt{t} . At L/\\sqrt{t} \\to 0 the transition behaves as a mean-field-like second-order phase transition. At \\vert H\\vert c-\\vert the slower tail behaves as -\\lnP˜ ≤ft\\vert H\\right\\vert 2L/t , whereas at \\vert H\\vert >\\vert H_c-\\vert it coincides with the slower tail of the GOE Tracy-Widom distribution.

  8. Thermal inactivation of foot-and-mouth disease virus in milk using high-temperature, short-time pasteurization.

    Science.gov (United States)

    Tomasula, P M; Kozempel, M F; Konstance, R P; Gregg, D; Boettcher, S; Baxt, B; Rodriguez, L L

    2007-07-01

    Previous studies of laboratory simulation of high temperature, short time pasteurization (HTST) to eliminate foot-and-mouth disease virus (FMDV) in milk have shown that the virus is not completely inactivated at the legal pasteurization minimum (71.7 degrees C/15 s) but is inactivated in a flow apparatus at 148 degrees C with holding times of 2 to 3 s. It was the intent of this study to determine whether HTST pasteurization conducted in a continuous-flow pasteurizer that simulates commercial operation would enhance FMDV inactivation in milk. Cows were inoculated in the mammary gland with the field strain of FMDV (01/UK). Infected raw whole milk and 2% milk were then pasteurized using an Arm-field pilot-scale, continuous-flow HTST pasteurizer equipped with a plate-and-frame heat exchanger and a holding tube. The milk samples, containing FMDV at levels of up to 10(4) plaque-forming units/mL, were pasteurized at temperatures ranging from 72 to 95 degrees C at holding times of either 18.6 or 36 s. Pasteurization decreased virus infectivity by 4 log10 to undetectable levels in tissue culture. However, residual infectivity was still detectable for selected pasteurized milk samples, as shown by intramuscular and intradermal inoculation of milk into naïve steers. Although HTST pasteurization did not completely inactivate viral infectivity in whole and 2% milk, possibly because a fraction of the virus was protected by the milk fat and the casein proteins, it greatly reduced the risk of natural transmission of FMDV by milk.

  9. Interactions of Grazing History, Cattle Removal and Time since Rain Drive Divergent Short-Term Responses by Desert Biota

    Science.gov (United States)

    Frank, Anke S. K.; Dickman, Chris R.; Wardle, Glenda M.; Greenville, Aaron C.

    2013-01-01

    Arid grasslands are used worldwide for grazing by domestic livestock, generating debate about how this pastoral enterprise may influence native desert biota. One approach to resolving this question is to experimentally reduce livestock numbers and measure the effects. However, a key challenge in doing this is that historical grazing impacts are likely to be cumulative and may therefore confound comparisons of the short-term responses of desert biota to changes in stocking levels. Arid areas are also subject to infrequent flooding rainfalls that drive productivity and dramatically alter abundances of flora and fauna. We took advantage of an opportunity to study the recent effects of a property-scale cattle removal on two properties with similarly varied grazing histories in central Australia. Following the removal of cattle in 2006 and before and after a significant rainfall event at the beginning of 2007, we sampled vegetation and small vertebrates on eight occasions until October 2008. Our results revealed significant interactions of time of survey with both grazing history and grazing removal for vascular plants, small mammals and reptiles. The mammals exhibited a three-way interaction of time, grazing history and grazing removal, thus highlighting the importance of careful sampling designs and timing for future monitoring. The strongest response to the cessation of grazing after two years was depressed reproductive output of plants in areas where cattle continued to graze. Our results confirm that neither vegetation nor small vertebrates necessarily respond immediately to the removal of livestock, but that rainfall events and cumulative grazing history are key determinants of floral and faunal performance in grassland landscapes with low and variable rainfall. We suggest that improved assessments could be made of the health of arid grazing environments if long-term monitoring were implemented to track the complex interactions that influence how native biota

  10. The First 90 Days of the New Middle School Principal in a Turnaround School: In-Depth Case Study of the Transition Period (First 90 Days)

    Science.gov (United States)

    Baeza, Marco A.

    2010-01-01

    This study analyzed skills, strategies, and theories that new middle school principals used to be successful during their transition period (the first 90 days) in turnaround schools. Based on research on transitions, three research questions guided the study: 1. Do middle school principals in a turnaround school situation find the transition…

  11. Speech Timing and Verbal Short-Term Memory: Evidence for Contrasting Deficits in Down Syndrome and Williams Syndrome

    Science.gov (United States)

    Jarrold, Christopher; Cowan, Nelson; Hewes, Alexa K.; Riby, Deborah M.

    2004-01-01

    This study explored the degree of verbal short-term memory deficit among individuals with Down syndrome and Williams syndrome, and the extent to which any such impairment could be accounted for by a relative slowing of rehearsal and output processes. Measures of serial recall and detailed assessments of speeded articulation for short and long…

  12. Enhancement mechanisms of short-time aerobic digestion for waste activated sludge in the presence of cocoamidopropyl betaine.

    Science.gov (United States)

    Xia, Siqing; Zhou, Yun; Eustance, Everett; Zhang, Zhiqiang

    2017-10-18

    Cocoamidopropyl betaine (CAPB), which is a biodegradable ampholytic surfactant, has recently been found to dramatically enhance the aerobic digestion of waste activated sludge (WAS) in short-time aerobic digestion (STAD) systems. Therefore, it is important to understand the mechanisms in which CAPB enhances WAS aerobic digestion performance. Results showed that CAPB could dramatically enhance the solubilization of soluble proteins (PN), polysaccharides (PS), nucleic acids (NA) and humic-like substances (HS) in the STAD system within the initial 2 h. Then PN, PS and NA gradually decreased, while HS showed only minor decease. In addition, CAPB increased the proportion of low MW fractions (biodegradable. Specific oxygen uptake rates and dehydrogenase enzyme activity results indicated that CAPB markedly improved the aerobic microorganism activities. Microbial community analyses and principle coordinate analyses (PCoA) revealed that CAPB increased the proportion of some functional microorganisms, including Proteobacteria, Planctomycetales, Acinetobacter, Pseudomonas and Aeromonas. The changes driven by CAPB could explain the enhanced performance of the STAD system for WAS aerobic treatment.

  13. Comparison of high pressure and high temperature short time processing on quality of carambola juice during cold storage.

    Science.gov (United States)

    Huang, Hsiao-Wen; Chen, Bang-Yuan; Wang, Chung-Yi

    2018-05-01

    This study validated high hydrostatic pressure processing (HPP) for achieving greater than 5-log reductions of Escherichia coli O157:H7 in carambola juice and determined shelf life of processed juice stored at 4 °C. Carambola juice processed at 600 MPa for 150 s was identified capable of achieving greater than 5.15-log reductions of E. coli O157:H7, and the quality was compared with that of high temperature short time (HTST)-pasteurized juice at 110 °C for 8.6 s. Aerobic, psychrotrophic, E. coli /coliform, and yeasts and moulds in the juice were reduced by HPP or HTST to levels below the minimum detection limit (HTST juices. However, HTST treatment significantly changed the color of juice, while no significant difference was observed between the control and HPP samples. HPP and HTST treatments reduced the total soluble solids in the juice, but maintained higher sucrose, glucose, fructose, and total sugar contents than untreated juice. The total phenolic and ascorbic acid contents were higher in juice treated with HPP than untreated and HTST juice, but there was no significant difference in the flavonoid content. Aroma score analysis showed that HPP had no effect on aroma, maintaining the highest score during cold storage. The results of this study suggest that appropriate HPP conditions can achieve the same microbial safety as HTST, while maintaining the quality and extending the shelf life of carambola juice.

  14. Crispy banana obtained by the combination of a high temperature and short time drying stage and a drying process

    Directory of Open Access Journals (Sweden)

    K. Hofsetz

    2005-06-01

    Full Text Available The effect of the high temperature and short time (HTST drying stage was combined with an air drying process to produce crispness in bananas. The fruit was dehydrated in an air drier for five minutes at 70°C and then immediately set at a HTST stage (130, 140, 150°C and 9, 12, 15 minutes and then at 70°C until water activity (a w was around 0.300. Crispness was evaluated as a function of water activity, using sensory and texture analyses. Drying kinetics was evaluated using the empirical Lewis model. Crispy banana was obtained at 140°C-12min and 150°C-15min in the HTST stage, with a w = 0.345 and a w = 0.363, respectively. Analysis of the k parameter (Lewis model suggests that the initial moisture content of the samples effects this parameter, overcoming the HTST effect. Results showed a relationship between sensory crispness, instrumental texture and the HTST stage.

  15. Treatment of Fungal Bioaerosols by a High-Temperature, Short-Time Process in a Continuous-Flow System▿

    Science.gov (United States)

    Jung, Jae Hee; Lee, Jung Eun; Lee, Chang Ho; Kim, Sang Soo; Lee, Byung Uk

    2009-01-01

    Airborne fungi, termed fungal bioaerosols, have received attention due to the association with public health problems and the effects on living organisms in nature. There are growing concerns that fungal bioaerosols are relevant to the occurrence of allergies, opportunistic diseases in hospitals, and outbreaks of plant diseases. The search for ways of preventing and curing the harmful effects of fungal bioaerosols has created a high demand for the study and development of an efficient method of controlling bioaerosols. However, almost all modern microbiological studies and theories have focused on microorganisms in liquid and solid phases. We investigated the thermal heating effects on fungal bioaerosols in a continuous-flow environment. Although the thermal heating process has long been a traditional method of controlling microorganisms, the effect of a continuous high-temperature, short-time (HTST) process on airborne microorganisms has not been quantitatively investigated in terms of various aerosol properties. Our experimental results show that the geometric mean diameter of the tested fungal bioaerosols decreased when they were exposed to increases in the surrounding temperature. The HTST process produced a significant decline in the (1→3)-β-d-glucan concentration of fungal bioaerosols. More than 99% of the Aspergillus versicolor and Cladosporium cladosporioides bioaerosols lost their culturability in about 0.2 s when the surrounding temperature exceeded 350°C and 400°C, respectively. The instantaneous exposure to high temperature significantly changed the surface morphology of the fungal bioaerosols. PMID:19201954

  16. High-temperature short-time pasteurisation of human breastmilk is efficient in retaining protein and reducing the bacterial count.

    Science.gov (United States)

    Klotz, Daniel; Joellenbeck, Mirjam; Winkler, Karl; Kunze, Mirjam; Huzly, Daniela; Hentschel, Roland

    2017-05-01

    Milk banks are advised to use Holder pasteurisation to inactivate the cytomegalovirus, but the process adversely affects the bioactive properties of human breastmilk. This study explored the antibacterial efficacy of an alternative high-temperature short-time (HTST) treatment of human breastmilk and its effect on marker proteins, compared with the Holder method. Breastmilk samples were obtained from 27 mothers with infants in a German neonatal intensive care unit. The samples were either heated to 62°C for five seconds using HTST or processed using Holder pasteurisation, at 63 ± 0.5°C for 30 minutes. Immunoglobulin A, lactoferrin, lysozyme, alkaline phosphatase and bile salt-stimulated lipase concentrations and bacterial colony-forming units/mL were measured before and after heating. HTST-treated samples retained higher rates of immunoglobulin A (95% versus 83%), alkaline phosphatase (6% versus 0%) and bile salt-stimulated lipase (0.8% versus 0.4%) than Holder pasteurisation samples (all p HTST treatment protocol retained some of the bioactive properties of human breastmilk and appeared to have similar antibacterial efficacy to Holder pasteurisation. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  17. Treatment of fungal bioaerosols by a high-temperature, short-time process in a continuous-flow system.

    Science.gov (United States)

    Jung, Jae Hee; Lee, Jung Eun; Lee, Chang Ho; Kim, Sang Soo; Lee, Byung Uk

    2009-05-01

    Airborne fungi, termed fungal bioaerosols, have received attention due to the association with public health problems and the effects on living organisms in nature. There are growing concerns that fungal bioaerosols are relevant to the occurrence of allergies, opportunistic diseases in hospitals, and outbreaks of plant diseases. The search for ways of preventing and curing the harmful effects of fungal bioaerosols has created a high demand for the study and development of an efficient method of controlling bioaerosols. However, almost all modern microbiological studies and theories have focused on microorganisms in liquid and solid phases. We investigated the thermal heating effects on fungal bioaerosols in a continuous-flow environment. Although the thermal heating process has long been a traditional method of controlling microorganisms, the effect of a continuous high-temperature, short-time (HTST) process on airborne microorganisms has not been quantitatively investigated in terms of various aerosol properties. Our experimental results show that the geometric mean diameter of the tested fungal bioaerosols decreased when they were exposed to increases in the surrounding temperature. The HTST process produced a significant decline in the (1-->3)-beta-d-glucan concentration of fungal bioaerosols. More than 99% of the Aspergillus versicolor and Cladosporium cladosporioides bioaerosols lost their culturability in about 0.2 s when the surrounding temperature exceeded 350 degrees C and 400 degrees C, respectively. The instantaneous exposure to high temperature significantly changed the surface morphology of the fungal bioaerosols.

  18. Evaluation of short-term physical weathering of a heavy fuel oil by use of time warping and PCA

    International Nuclear Information System (INIS)

    Malmquist, L.M.V.; Olsen, R.R.; Christensen, J.H.; Andersen, O.

    2005-01-01

    An estimated 1,140 billion tons of oil was accidentally spilled to the environment during the 1990s. These spills present an ecotoxicologic risk due to the presence of toxic and mutagenic compounds in the oil. Oil is affected by short term and long term weathering processes such as evaporation, dissolution, dispersion, emulsification, photodegradation and biodegradation. Physical weathering processes change the composition of the oil but they do not alter the oil components. Gas chromatography and mass spectrometry can characterize the compositional changes resulting from evaporation. However, the process depends on subjective analysis because it is based on manual interpretation of results and visual inspection. This paper presents a rapid and objective method to compare oil sample compositions. The method is based on automated data preprocessing involving baseline removal, alignment of chromatograms using correlation optimized warping (COW) and normalization. Preprocessed data is analyzed by principal component analysis (PCA) based on the total chromatograms. The method has successfully resolved the effects of evaporation and dissolution processes and showed clear dependence of time, but it did not completely resolve the effect of weathering from the analytical variability because better quality data is required. 21 refs., 3 figs

  19. Relationship of Corneal Pain Sensitivity With Dry Eye Symptoms in Dry Eye With Short Tear Break-Up Time.

    Science.gov (United States)

    Kaido, Minako; Kawashima, Motoko; Ishida, Reiko; Tsubota, Kazuo

    2016-03-01

    The purpose of this prospective comparative study was to investigate corneal sensitivity in subjects with unstable tear film, with and without dry eye (DE) symptoms. Forty-one eyes of 41 volunteers (mean age: 45.1 ± 9.4 years; age range, 23-57 years), with normal tear function and ocular surface except for tear stability, were studied. The eyes were divided into two groups depending on the presence or absence of DE symptoms: 21 eyes with DE symptoms (symptomatic group); and 20 eyes without DE symptoms (asymptomatic group). Three types of corneal sensitivity values were measured using a Cochet-Bonnet esthesiometer: the sensitivity for perception of touch (S-touch), the sensitivity for blinking (S-blink), and the sensitivity for pain (S-pain). Mean S-blink and S-pain were significantly higher in the symptomatic group than in the asymptomatic group (P 0.05). Corneal sensitivity for blinking and pain evoked by increased stimuli was higher in the symptomatic group (subjects with short break-up time DE) compared with subjects who have no DE symptoms despite decreased tear stability. The presence of both tear instability and hyperesthesia, rather than tear instability alone, may contribute to DE pathogenesis.

  20. Evidence of increased endometrial vascular permeability at the time of implantation in the short-nosed fruit bat, Cyanopterus sphinx.

    Science.gov (United States)

    Pakrasi, Pranab Lal; Tiwari, Anjana

    2007-09-01

    Early embryonic development and implantation were studied in tropical short-nosed fruit bat Cyanopterus sphinx. We report preimplantation development and embryo implantation. Different stages of cleavage were observed in embryo by direct microscopic examination of fresh embryos after retrieving them either from the oviduct or the uterus at different days, up to the day of implantation. Generally, the embryos enter the uterus at the 8-cell stage. Embryonic development continued without any delay and blastocyst were formed showing attachment to the uterine epithelium at the mesometrial side of the uterus. A distinct blue band was formed in the uterus. The site of blastocyst attachment was visualized as a blue band following intravenous injection of pontamine blue. Implantation occurred 9+/-0.7 days after mating. This study reports that bat embryonic development can be studied like other laboratory animals and that this bat shows blue dye reaction, indicating the site and exact time of implantation. This blue dye reaction can be used to accurately find post-implantational delay. We prove conclusively that this species of tropical bat does not have any type of embryonic diapause.