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Sample records for shih yu hua

  1. Surface-enhanced Raman scattering study of the healing of radial fractures treated with or without Huo-Xue-Hua-Yu decoction therapy

    Science.gov (United States)

    Chen, Weiwei; Huang, Hao; Chen, Rong; Feng, Shangyuan; Yu, Yun; Lin, Duo; Lin, Jia

    2014-11-01

    This study aimed to assess, through surface-enhanced Raman scattering (SERS) spectroscopy, the incorporation of calcium hydroxyapatite (CHA ~960 cm-1) and other biochemical substances in the repair of complete radial fractures in rabbits treated with or without Huo-Xue-Hua-Yu decoction (HXHYD) therapy. A total of 18 rabbits with complete radial fractures were randomly divided into two groups; one group was treated with HXHYD therapy and the other without therapy acted as a control. The animals were sacrificed at 15, 30 and 45 d after surgery. Specimens were routinely prepared for SERS measurement and high quality SERS spectra from a mixture of bone tissues and silver nanoparticles were obtained. The mineral-to-matrix ratios from the control and treated groups were calculated. Results showed that both deposition content of CHA measured by SERS spectroscopy and the mineral-to-matrix ratio in the treated group were always greater than those of the control group during the experiment, demonstrating that HXHYD therapy is effective in improving fracture healing and that SERS spectroscopy might be a novel tool to assess fracture healing.

  2. Sheng-ji Hua-yu formula promotes diabetic wound healing of re-epithelization via Activin/Follistatin regulation.

    Science.gov (United States)

    Kuai, Le; Zhang, Jing-Ting; Deng, Yu; Xu, Shun; Xu, Xun-Zhe; Wu, Min-Feng; Guo, Dong-Jie; Chen, Yu; Wu, Ren-Jie; Zhao, Xing-Qiang; Nian, Hua; Li, Bin; Li, Fu-Lun

    2018-01-29

    Sheng-ji Hua-yu(SJHY) formula is one of the most useful Traditional Chinese medicine (TCM) in the treatment of the delayed diabetic wound. However, elucidating the related molecular biological mechanism of how the SJHY Formula affects excessive inflammation in the process of re-epithelialization of diabetic wound healing is a task urgently needed to be fulfilled. The objectives of this study is to evaluate the effect of antagonisic expression of pro-/anti-inflammatory factors on transforming growth factor-β(TGF-β) superfamily (activin and follistatin) in the process of re-epithelialization of diabetic wound healing in vivo, and to characterize the involvement of the activin/follistatin protein expression regulation, phospho-Smad (pSmad2), and Nuclear factor kappa B p50 (NF-kB) p50 in the diabetic wound healing effects of SJHY formula. SJHY Formula was prepared by pharmaceutical preparation room of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine. Diabetic wound healing activity was evaluated by circular excision wound models. Wound healing activity was examined by macroscopic evaluation. Activin/follistatin expression regulation, protein expression of pSmad2 and NF-kB p50 in skin tissue of wounds were analyzed by Real Time PCR, Western blot, immunohistochemistry and hematoxylin and eosin (H&E) staining. Macroscopic evaluation analysis showed that wound healing of diabetic mice was delayed, and SJHY Formula accelerated wound healing time of diabetic mice. Real Time PCR analysis showed higher mRNA expression of activin/follistatin in diabetic delayed wound versus the wound in normal mice. Western Blot immunoassay analysis showed reduction of activin/follistatin proteins levels by SJHY Formula treatment 15 days after injury. Immunohistochemistry investigated the reduction of pSmad2 and NF-kB p50 nuclear staining in the epidermis of diabetic SJHY versus diabetic control mice on day 15 after wounding. H&E staining revealed that SJHY Formula

  3. Use of Shih in Chinese Operational Art

    Science.gov (United States)

    2016-05-26

    These include leaders seeking to manipulate context, build troop morale through context, use an indirect approach, and exploit propensity within a...characteristics help determine whether or not shih was a factor in a given conflict. These include leaders seeking to manipulate context, build troop morale ...U.S. Army War College, 2011), ix-x; William H. Mott and Jae Chang Kim, The Philosophy of Chinese Military Culture: Shih vs. Li (New York, NY: Palgrave

  4. [Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu] / Ago Künnap

    Index Scriptorium Estoniae

    Künnap, Ago, 1941-

    2010-01-01

    Arvustus: Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu = Chinese language and languages of northern Europe. Beijing : Zhongguo she hui ke xue chu ban she, 2008

  5. [Herbological study of the botanical origin of Chinese crude drugs "Du-hua" and "Qiang-hua" in ancient China].

    Science.gov (United States)

    Mikage, Masayuki; Ochimori, Akane

    2007-01-01

    The Chinese crude drug Qiang-hua was listed as an alias of Du-hua in Shen-nong-ben-cao-jing, an herbal journal written during the Han Dynasty, China. Du-hua and Qiang-hua are recognized as different herbs in China these days; the main botanical origin of Du-hua is Angelica spp. and that of Qiang-hua is Notopterygium spp., of the family Umbelliferae. To make clear the botanical origins of Du-hua and Qiang-hua in ancient China, the authors made a herbological study. The findings were as follows: the name of Qiang-hua was given to the genuine Du-hua, which is produced in Qiang Province, an ancient province located in northwest China; the botanical origin of Qiang-hua is presumed to be Notopterygium incisum Ting ex H.T. Chang and N. forbesii Boissieu based on both the morphology and habitat written in ancient herbal journals. Both species are prescribed as having the plant origin of Qiang-hua in the present Chinese Pharmacopoeia. Therefore, we concluded that Du-hua and Qiang-hua were essentially the same drug, and were originally derived from the Notopterygium species in ancient China.

  6. A case of gastrinoma in a Shih-Tzu dog.

    Science.gov (United States)

    Fukushima, Ushio; Sato, Miyuki; Okano, Shozo; Aramaki, Yoshitaka; Ito, Hiroshi; Yoshioka, Kazuki; Oyamada, Toshifumi; Uechi, Masami

    2004-03-01

    A five-year-old male Shih-Tzu dog presented with severe vomiting and weight loss. The clinical signs were successfully improved by an eight-day treatment with an H(2)-receptor antagonist, gastrointestinal protectant and antibiotics. Ten days later, however, recurrence of vomiting was seen despite continuous medical treatment. Based on clinical signs and the results of various diagnostic tests including CBC, biochemical analysis, contrast radiography, and endoscopy, a duodenal or pancreatic neoplasm was suspected and exploratory laparotomy was conducted. Some swollen pancreatic regions were found, and biopsy of the pancreas indicated the diagnosis of a gastrin-secreting tumor. Consequently, based on a high serum gastrin level as well as clinical signs and immunohistological findings, we diagnosed the disease as canine gastrinoma, a rare tumor of the pancreas.

  7. Technology Education and Technology Teacher Education in Taiwan, R.O.C. = Zhong Hua Min Guo Ke Ji Jiao Yu Ji qi shi zi Jiao Yu.

    Science.gov (United States)

    Lee, Lung-Sheng Steven; Wang, Cheng-Pin Peter; Wang, Yen-chao; Shih, Neng-Mu; Yeh, Chung-ching

    Technology education in Taiwan begins with craft work at the elementary school level, and the most important point is the practical application. All junior high school students are required to take the Living Technology course. Content includes technology and life, information and communication, construction and manufacturing, and energy and…

  8. Approximate solutions of the Wei Hua oscillator using the Pekeris ...

    Indian Academy of Sciences (India)

    The approximate analytical bound-state solutions of the Schrödinger equation for the. Wei Hua oscillator are carried out in N-dimensional space by taking Pekeris approximation scheme to the orbital centrifugal term. Solutions of the corresponding hyper-radial equation are obtained using the conventional Nikiforov–Uvarov ...

  9. Eigensolutions, Shannon entropy and information energy for modified Tietz-Hua potential

    Science.gov (United States)

    Onate, C. A.; Onyeaju, M. C.; Ituen, E. E.; Ikot, A. N.; Ebomwonyi, O.; Okoro, J. O.; Dopamu, K. O.

    2018-04-01

    The Tietz-Hua potential is modified by the inclusion of De ( {{Ch - 1}/{1 - C_{h e^{{ - bh ( {r - re } )}} }}} )be^{{ - bh ( {r - re } )}} term to the Tietz-Hua potential model since a potential of such type is very good in the description and vibrational energy levels for diatomic molecules. The energy eigenvalues and the corresponding eigenfunctions are explicitly obtained using the methodology of parametric Nikiforov-Uvarov. By putting the potential parameter b = 0, in the modified Tietz-Hua potential quickly reduces to the Tietz-Hua potential. To show more applications of our work, we have computed the Shannon entropy and Information energy under the modified Tietz-Hua potential. However, the computation of the Shannon entropy and Information energy is an extension of the work of Falaye et al., who computed only the Fisher information under Tietz-Hua potential.

  10. Operational and research activities of Tsing Hua open pool reactor

    International Nuclear Information System (INIS)

    Wang, T.-K.; Tseng, D.-L.; Chou, H.-P.; Onyang Minsun

    1988-01-01

    Tsing Hua Open Pool Reaction (THOR) is the first nuclear reactor to become operational in Taiwan. It reached its first critical on April 13, 1961. Until now, THOR has been operated successfully for 27 years. The major missions of THOR include radioisotope production, neutron activation analysis, nuclear science and engineering researches, education, and personnel training. The THOR was originally loaded with HEU MTR-type fuels. A gradual fuel replacing program using LEU TRIGA fuel to replace MTR started in 1977. By 1987, THOR was loaded with all TRIGA fuels. This paper gives a brief history of THOR, its current status, the core conversion work, some selected research topics, and its improvement plan. (author)

  11. Calming effect of orally administered γ-aminobutyric acid in Shih Tzu dogs.

    Science.gov (United States)

    Uetake, Katsuji; Okumoto, Ayano; Tani, Noriko; Goto, Akihiro; Tanaka, Toshio

    2012-12-01

    The calming effects of γ-aminobutyric acid (GABA) by oral administration were investigated in four adult Shih Tzu dogs. Three dosage levels (1, 2 and 4 mg/kg body weight) and non-administration were tested by an increase and decrease method. Changes in activity (for 1.5 h) and urinary cortisol levels (pre-administration, 3 and 7 h later) of dogs were monitored after administration. Without reference to dosage level, the mean times spent standing (P = 0.06), sitting (P level was observed at 7 h after administration (P GABA exerts calming effects on dogs as well as humans. © 2012 The Authors. Animal Science Journal © 2012 Japanese Society of Animal Science.

  12. Double Intussusception in a Shih-Tzu Puppy: The Triple-Circle Sign

    Directory of Open Access Journals (Sweden)

    J. M. Kim, S. S. Kang1, G. Kim and S. H. Choi*

    2012-05-01

    Full Text Available Intussusception is a common surgical disorder in puppies. Double intussusception (DI however, is an extremely rare form of this pathology. The authors report a case of a 3-month-old, Shih-Tzu puppy referred to Veterinary Medical Center of Chungbuk National University, Korea with symptoms of abdominal discomfort, intermittent vomiting and bloody diarrhea for 5 days. Ultrasonographic examination of the left mid-abdominal region revealed a mass with a ‘triple case’ sign completely different from the classic ‘target sign’. The surgical intervention confirmed it to be an ileocecal DI in ascending colon. The case emphasizes the rare ‘triple case’ sign as a descriptive finding on ultrasonography in DI presentations.

  13. Hua Loo-Keng's Popularization of Mathematics and the Cultural Revolution.

    Science.gov (United States)

    Hudeček, Jiří

    2017-09-01

    Before 1966, Chinese mathematician Hua Loo-Keng had singled out "Two Methods" as a way to truly applied and useful mathematics. The Overall Planning Method, based on the Critical Path Method widely used in USA, mostly appealed to middle and upper management. This limited its spread during the Cultural Revolution. The Optimum Selection Method, also of US origin, was more mass-oriented and ready for popularization. Nevertheless, Hua met resistance from leftist radicals, whose ideological objections sprang from an underlying power struggle. Hua built popularization teams, mostly from talented younger people whose careers were disrupted by the Cultural Revolution, and thus opened a path for many of them to important roles in China's scientific infrastructure after 1976. Hua Loo-Keng's efforts, while interrupted during the Cultural Revolution and the subsequent political campaigns, were also helped by the populist ethos of the movement, and by the lack of other non-political endeavors at that time. In this sense, the Cultural Revolution gave Hua Loo-Keng's popularization its importance and long-term impact. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Optical properties of the Tietz-Hua quantum well under the applied external fields

    Science.gov (United States)

    Kasapoglu, E.; Sakiroglu, S.; Ungan, F.; Yesilgul, U.; Duque, C. A.; Sökmen, I.

    2017-12-01

    In this study, the effects of the electric and magnetic fields as well as structure parameter- γ on the total absorption coefficient, including linear and third order nonlinear absorption coefficients for the optical transitions between any two subband in the Tietz-Hua quantum well have been investigated. The optical transitions were investigated by using the density matrix formalism and the perturbation expansion method. The Tietz-Hua quantum well becomes narrower (wider) when the γ - structure parameter increases (decreases) and so the energies of the bound states will be functions of this parameter. Therefore, we can provide the red or blue shift in the peak position of the absorption coefficient by changing the strength of the electric and magnetic fields as well as the structure parameters and these results can be used to adjust and control the optical properties of the Tietz-Hua quantum well.

  15. A Case Study of Synchronous Distance Learning Between Shih Chien University and Beijing Foreign Studies University

    Directory of Open Access Journals (Sweden)

    Yen-Fen Lo

    2016-08-01

    Full Text Available Shih Chien University and Beijing Foreign Studies University collaboratively launched a project to offer synchronous distance learning courses on "Case Studies of Taiwanese Entrepreneurs" since February 2012. The three objectives of this study are: (1 to explore the Cross-Strait students' motives for selecting the course; (2 to examine the students' accommodation condition before and after completing the course; (3 to discuss the student's level of satisfaction of the course. This study uses qualitative data from case study interviews conducted in the second year of the project based on the research focus of the Cross-Strait students' motivation and satisfaction of the course. The research analysis tools are content analysis and theory triangulation. The findings are: (1 Cross-Strait students are motivated by their curiosity about the course, interest in the contents, and willingness to experience the novelty of distance learning to select the course; (2 the results of Cross-Strait students' accommodation condition are correlated to their interactions with the professor, the familiarity with the materials, the quality of the communication equipment, and the clarity of the images; (3 Cross-Strait students all accept the method of synchronous distance learning; (4 the quality of communication equipment has the lowest level of satisfaction.

  16. Factors Associated with Fear of Falling among Community-Dwelling Older Adults in the Shih-Pai Study in Taiwan

    OpenAIRE

    Chang, Hsiao-Ting; Chen, Hsi-Chung; Chou, Pesus

    2016-01-01

    Background Fear of falling is an important risk indicator for adverse health related outcomes in older adults. However, factors associated with fear of falling among community-dwelling older adults are not well-explored. Objectives To explore the quality of life and associated factors in fear of falling among older people in the Shih-Pai area in Taiwan. Methods This community-based survey recruited three thousand eight hundred and twenty-four older adults aged ? 65 years. The measurements inc...

  17. Anatomical contributions to plant taxonomy II. The affinities of Hua Pierre and Afrostyrax Perkins et Gilg

    NARCIS (Netherlands)

    Baas, P.

    1972-01-01

    Vegetative anatomy, fruit and seed structure, and pollen morphology of Hua and Afrostyrax (tropical West and Central Africa) are described in detail. The two genera have many anatomical characters in common (see anatomical family diagnosis on p. 182) but are sufficiently different from other

  18. Association between perilipin gene polymorphisms and body weight traits in Jinmao Hua chickens

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    T. Li

    2017-09-01

    Full Text Available The perilipin gene (PLIN plays a crucial role in lipid metabolism and fat deposition. In order to reveal the genetic effects of PLIN polymorphisms on body weight (BW traits in chickens, PLIN gene polymorphisms in 322 Jinmao Hua chickens were detected by PCR-SSCP and DNA sequencing methods. For PLIN primer pair 1, five genotypes (AA, AB, BB, JJ and JL were detected in the Jinmao Hua chicken population and three mutations (g.1889C > T, g.1904T > C and g.1922C > T were revealed by gene sequencing. For PLIN primer pair 2, three genotypes (CC, CD and DD were detected in the same population and two mutations (g.2014A > G and g.2020C > T were revealed by gene sequencing. Least squares analysis showed that individuals with the JJ and CD genotypes performed better than the other Jinmao Hua chicken genotypes. Based on the five SNPs, the frequency distributions of the eight haplotypes were estimated with PHASE2.1 software. C-T-C-G-T was the major haplotype with a frequency of 58.6957 %, while the frequency of C-C-C-A-C was less than 1 %. Fourteen diplotypes were obtained from the eight haplotypes. H1H1 was the dominant diplotype with a frequency of 47.205 %. Least squares analysis indicated that BW with the H3H3 diplotype was the lowest, while the H2H2 diplotype was the highest, suggesting that selecting for the H3H3 diplotype improved the BW traits of Jinmao Hua chickens. The findings of this study should be useful to expand the theoretical basis of the role the PLIN in poultry molecular breeding of poultry.

  19. Jing Tong Yu Shu , a traditional Chinese medicine, suppresses IL ...

    African Journals Online (AJOL)

    Purpose: To evaluate the effect of a traditional Chinese medicine, Jing Tong Yu Shu (JTYS) on endometriosis in a rat surgical model. Methods: Endometriosis was induced in 40 female rats. The rats were randomly divided into 4 groups: three JTYS groups given different doses of the drug, and a saline group. After four ...

  20. Information from Yüan Shih on the Military Cooperation between the Golden Horde and the Yüan Dynasty.

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    Zhu-Cheng Zhao.

    2016-12-01

    Full Text Available Research objective: to reveal relations in military affairs between the Golden Horde and the Yüan Dynasty on the basis of the data of the Chinese dynastic history Yüan shih. Research materials: because of the large distance between these medieval Chinggisid powers, internecine strife between the houses of the Jochids and Toluids, armed conflicts between Arik-Boke and Kublai and due to the fact that the rulers of the Jochid ulus supported Arik-Boke, their state became independent from the Great Mongol Empire. Later on, long-term military conflicts and political turmoil interrupted communication between Sarai and Khanbalik. The Jochid ulus and the Yuan dynasty conducted their own foreign policies. However, communication between them was not interrupted and some information from the Golden Horde still fall in Chinese chronicles. One of the important and fundamental sources relating to the Mongol history is Yüan shih (History of the Yüan Dynasty. This written source contains some materials (although in fragments revealing the nature of the relations between the Yuan Dynasty and the Golden Horde. Research results and novelty: the author has provided information that the military units composed of the peoples of the Golden Horde (primarily of the Ases and Kipchaks, as well as of the Russians were among the troops in the Yüan Empire. At the same time, their proportion was significant both in the composition of commanding staff, as well as among ordinary soldiers. However, the source does not contain any information about the conditions under which these warriors arrived in China as well as about the routes they were moving. It is indisputable fact that they were sent to the Far East from the Jochid ulus during the highest power of this state in the reign of khan Uzbek. Perhaps it was an indication that the Yüan emperor displayed his authority over Sarai Khan in the political sense as well.

  1. [Autobiography of modern acupuncturist Yu Shu-zhuang].

    Science.gov (United States)

    Li, Jia-jian' i; Guo, Jing; Yu, Zhen-zhong; Wang, Lin-peng

    2014-11-01

    Professor YU Shu-zhuang is a distinguished acupuncturist in China. He has practiced the TCM acupuncture-moxibustion clinical, educational and scientific research for 60 years in his life. In clinic, he summarized the experiences "five-ming first"; in treatment, he insisted "dredging" and "regulating", protecting the function of spleen and stomach, and needles should be less but specific. In the meanwhile, he made a deep study on the function and clinical effects of specific acupoints, and used the research results of propagated sensation along channel to guide clinical treatment, forming his special academic points. Professor YU has educated a great number of acupuncture-moxibustion talents in China and foreign countries, making great contribution to the popularization of acupuncture-moxibustion in the worldwide.

  2. CA-Markov Analysis of Constrained Coastal Urban Growth Modeling: Hua Hin Seaside City, Thailand

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    Rajendra Shrestha

    2013-04-01

    Full Text Available Thailand, a developing country in Southeast Asia, is experiencing rapid development, particularly urban growth as a response to the expansion of the tourism industry. Hua Hin city provides an excellent example of an area where urbanization has flourished due to tourism. This study focuses on how the dynamic urban horizontal expansion of the seaside city of Hua Hin is constrained by the coast, thus making sustainability for this popular tourist destination—managing and planning for its local inhabitants, its visitors, and its sites—an issue. The study examines the association of land use type and land use change by integrating Geo-Information technology, a statistic model, and CA-Markov analysis for sustainable land use planning. The study identifies that the land use types and land use changes from the year 1999 to 2008 have changed as a result of increased mobility; this trend, in turn, has everything to do with urban horizontal expansion. The changing sequences of land use type have developed from forest area to agriculture, from agriculture to grassland, then to bare land and built-up areas. Coastal urban growth has, for a decade, been expanding horizontally from a downtown center along the beach to the western area around the golf course, the southern area along the beach, the southwest grassland area, and then the northern area near the airport.

  3. The optimal version of Hua's fundamental theorem of geometry of rectangular matrices

    CERN Document Server

    Semrl, Peter

    2014-01-01

    Hua's fundamental theorem of geometry of matrices describes the general form of bijective maps on the space of all m\\times n matrices over a division ring \\mathbb{D} which preserve adjacency in both directions. Motivated by several applications the author studies a long standing open problem of possible improvements. There are three natural questions. Can we replace the assumption of preserving adjacency in both directions by the weaker assumption of preserving adjacency in one direction only and still get the same conclusion? Can we relax the bijectivity assumption? Can we obtain an analogous result for maps acting between the spaces of rectangular matrices of different sizes? A division ring is said to be EAS if it is not isomorphic to any proper subring. For matrices over EAS division rings the author solves all three problems simultaneously, thus obtaining the optimal version of Hua's theorem. In the case of general division rings he gets such an optimal result only for square matrices and gives examples ...

  4. Excited collective states of nuclei within Bohr Hamiltonian with Tietz-Hua potential

    Energy Technology Data Exchange (ETDEWEB)

    Chabab, M.; El Batoul, A.; Lahbas, A.; Oulne, M. [Cadi Ayyad University, High Energy Physics and Astrophysics Laboratory, Faculty of Sciences Semlalia, Marrakesh (Morocco); Hamzavi, M. [University of Zanjan, Department of Physics, Zanjan (Iran, Islamic Republic of)

    2017-07-15

    In this paper, we present new analytical solutions of the Bohr Hamiltonian problem that we derived with the Tietz-Hua potential, here used for describing the β-part of the nuclear collective potential plus that of the harmonic oscillator for the γ-part. Also, we proceed to a systematic comparison of the numerical results obtained with this kind of β-potential with others which are widely used in such a framework as well as with the experiment. The calculations are carried out for energy spectra and electromagnetic transition probabilities for γ-unstable and axially symmetric deformed nuclei. In the same frame, we show the effect of the shape flatness of the β-potential beyond its minimum on transition rates calculations. (orig.)

  5. Dynamics analysis of fractional order Yu-Wang system

    Science.gov (United States)

    Bhalekar, Sachin

    2013-10-01

    Fractional order version of a dynamical system introduced by Yu and Wang (Engineering, Technology & Applied Science Research, 2, (2012) 209-215) is discussed in this article. The basic dynamical properties of the system are studied. Minimum effective dimension 0.942329 for the existence of chaos in the proposed system is obtained using the analytical result. For chaos detection, we have calculated maximum Lyapunov exponents for various values of fractional order. Feedback control method is then used to control chaos in the system. Further, the system is synchronized with itself and with fractional order financial system using active control technique. Modified Adams-Bashforth-Moulton algorithm is used for numerical simulations.

  6. Treatment of Goiter with Traditional Chinese Medicine Regimen Xing Qi Hua Ying Tang: A Clinical Study on 72 Patients with Multinodular and Diffuse Goiter.

    Science.gov (United States)

    Yang, Ming-Li; Lu, Bo

    2018-04-01

    The present work aimed to further explore the therapeutic potential of Xing Qi Hua Ying Tang (XQHYT) by conducting a systemic clinical study in patients with goiter. Seventy-two patients with either multinodular or diffuse goiter were enrolled and randomly assigned into treatment group receiving XQHYT (n = 36) and control group receiving Hai Zao Yu Hu Tang (n = 36). Traditional Chinese Medicine Hospital of Shanxi. Patients were diagnosed multinodular goiter or diffuse goiter resulting from Qi stagnation. All patients took the extract twice a day (100 mL each time) for two courses of treatment, of which a single course lasted for 3 months. Before the treatment was commenced and after the completion of the treatment, general body checks, thyroid function test, and goiter size examination were performed. Scoring of the clinical symptoms using Chinese medicine symptomatology was also done. The symptom score of the treatment group was significantly lower than that of the control group (treatment group, 8.26 ± 2.62; control group, 10.02 ± 2.62; p < 0.05). Substantial reduction in goiter size was seen in 82.3% of XQHYT-treated patients, whereas in the control group only 67.7% of patients exhibited constricted goiter. When assessed by both the Chinese medicine criteria and goiter size, the overall effective rate of the treatment group was 91.2%, whereas that of the control group was only 67.7%. The difference was statistically significant (p < 0.05). XQHYT did not affect the normal functions of liver, kidney, and heart. For both groups of patients, their levels of thyroid-stimulating hormone, free T4 and free T3 were normal before the treatment, and were not affected by the treatment. XQHYT was shown to be a promising therapeutic regimen for the treatment of goiter. The herbal regimen ameliorated clinical symptoms of patients that were accompanied with reduction in the size of goiter.

  7. Factors Associated with Fear of Falling among Community-Dwelling Older Adults in the Shih-Pai Study in Taiwan.

    Directory of Open Access Journals (Sweden)

    Hsiao-Ting Chang

    Full Text Available Fear of falling is an important risk indicator for adverse health related outcomes in older adults. However, factors associated with fear of falling among community-dwelling older adults are not well-explored.To explore the quality of life and associated factors in fear of falling among older people in the Shih-Pai area in Taiwan.This community-based survey recruited three thousand eight hundred and twenty-four older adults aged ≥ 65 years. The measurements included a structured questionnaire, including quality of life by using Short-Form 36, and information of fear of falling, fall history, demographics, medical conditions, insomnia, sleep quality, depression and subjective health through face-to-face interviews.A total of 53.4% of participants reported a fear of falling. The rate of fear of falling was higher in female subjects. Subjects with fear of falling had lower Short Form-36 scores both for men and women. Falls in the previous year, older age, insomnia, depression and worse subjective health were correlates of fear of falling for both sexes. Male-specific associations with fear of falling were the accessibility of medical help in an emergency, diabetes mellitus and stroke. In parallel, cardiovascular diseases were a female-specific correlate for fear of falling.Fear of falling is prevalent among community-dwelling older adults. It is seems that there are gender differences in fear of falling with respect to the prevalence and associated factors in older adults. Gender differences should be considered when planning prevention and intervention strategies for fear of falling among older people.

  8. Yu.S. Osipov's work in mathematical control theory

    International Nuclear Information System (INIS)

    Kryazhimskiy, Arkady A

    2006-01-01

    This paper gives an overview of Yu.S. Osipov's work in mathematical control theory, including development of the theory of positional differential games for control systems with time delay; analysis of the phenomenon of infinite dimensionality of the state space of a dynamical system in the context of differential games; development of the theory of dynamical inversion (dynamical regularization) for finite- and infinite-dimensional control systems; applications of methods of the theory of positional differential games beyond the scope of the theory itself; work on new differential-game methods and on methods of control under incomplete information. The author of this overview is the first student of Osipov, and also his longstanding colleague.

  9. Dr. Yu Wang, Director, Natural Science Division, National Science Council, Taiwan

    CERN Document Server

    Patrice Loïez

    2001-01-01

    Photo 01: L. to r.: Dr. Philippe Bloch, CERN CMS ECAL Deputy Project Manager, Dr. Yu Wang, Dr. Etiennette Auffray, CERN, responsible of the CERN ECAL Regional Centre. Photo 02: L. to r.: Dr. Yu Wang, Dr. Philippe Bloch, Dr. Apollo GO, National Central University, Taiwan, Dr. Etiennette Auffray.

  10. Comments on Yu N Parkhomenko's paper 'Role of aberration effects in dispersive cavities'

    International Nuclear Information System (INIS)

    Anokhov, S P

    1999-01-01

    The legitimacy of the approach, proposed by Yu N Parkhomenko for dealing with the operation of solid-state lasers with dispersive cavities, is discussed. Additional information is provided on the neodymium glass laser, used in the present author's experiment. Comment on A Yu N Parkhomenko 1998 Quantum Electron. 28 1102. (discussion)

  11. A novel approach to the pharmacodynamic modelling of 131I-HUA33 antibody in patients with colorectal carcinoma

    International Nuclear Information System (INIS)

    Papenfuss, A.T.; Chong, G.; Schleyer, P.; O'Keefe, G.J.; Scott, A.M.

    2003-01-01

    Full text: The humanised monoclonal antibody, huA33, has been the subject of intense investigation as a candidate for targeted radiotherapy. HuA33 exhibits strong uptake by colorectal cancers for up to 6 weeks post-infusion, and also by normal colonic epithelium, however colon clearance occurs within a 1-2 week period. This is reflected in the lack of gastro-intestinal toxicity in previous trials of 131 I-murine A33. Models of huA33 normal tissue uptake and excretion, which are useful tools for determining time activity curves and organ residence times, are complicated by the fact that colonic epithelial cells are shed when they reach the age of 6-7 days. This can, in principle, be approximated by an exponential loss term from a colon compartment. The problem with such a simple model is in accurately estimating the loss rate. A novel approach is introduced here in which the colonic epithelium is not represented by a single well-mixed compartment, but instead by an average over many sub-compartments. Each sub-compartment represents colon epithelial cells of a single age. When the age a sub-compartment reaches the average lifetime of a colonic epithelial cell, the sub-compartment is emptied. Numerical results based on autoradiography and planar imaging of a colon, surgically resected one week after infusion of labelled antibody are shown. Copyright (2003) The Australian and New Zealand Society of Nuclear Medicine Inc

  12. Tuning Features of Chinese Folk Song Singing: A Case Study of Hua'er Music.

    Science.gov (United States)

    Yang, Yang; Welch, Graham; Sundberg, Johan; Himonides, Evangelos

    2015-07-01

    The learning and teaching of different singing styles, such as operatic and Chinese folk singing, was often found to be very challenging in professional music education because of the complexity of varied musical properties and vocalizations. By studying the acoustical and musical parameters of the singing voice, this study identified distinctive tuning characteristics of a particular folk music in China-Hua'er music-to inform the ineffective folk singing practices, which were hampered by the neglect of inherent tuning issues in music. Thirteen unaccompanied folk song examples from four folk singers were digitally audio recorded in a sound studio. Using an analyzing toolkit consisting of Praat, PeakFit, and MS Excel, the fundamental frequencies (F0) of these song examples were extracted into sets of "anchor pitches" mostly used, which were further divided into 253 F0 clusters. The interval structures of anchor pitches within each song were analyzed and then compared across 13 examples providing parameters that indicate the tuning preference of this particular singing style. The data analyses demonstrated that all singers used a tuning pattern consisting of five major anchor pitches suggesting a nonequal-tempered bias in singing. This partly verified the pentatonic scale proposed in previous empirical research but also argued a potential misunderstanding of the studied folk music scale that failed to take intrinsic tuning issues into consideration. This study suggests that, in professional music training, any tuning strategy should be considered in terms of the reference pitch and likely tuning systems. Any accompanying instruments would need to be tuned to match the underlying tuning bias. Copyright © 2015 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  13. The emergence of the ecological mind in Hua-Yen/Kegon Buddhism and Jungian psychology.

    Science.gov (United States)

    Cambray, Joe

    2017-02-01

    The complexity associated with deep interconnectedness in nature is beginning to be articulated and elaborated in the field of ecological studies. While some parallels to the psyche have been made and the field of Eco-psychology has been developing, Jung's explicit contribution by way of the image of rhizomes has not been considered in detail. Philosopher Gilles Deleuze acknowledges borrowing the term from Jung, though he disagreed with Jung's Empedoclean use of the term. The paper presents some fundamental properties of rhizomes along with contemporary scientific research on mycorrhizal (fungal) networks. Comparisons are made, first with classical symbolic forms, demonstrating some overlap but also some differences. Then comparison of rhizomal networks is made to those found both in mammalian brains and in recent images of the 'cosmic web'. While no hard conclusions can be drawn from these images, their remarkable similarities are suggestive of a need to reconsider what is meant by 'intelligence'. The cosmic web is one of the largest structures in the known universe (clusters of galaxies which form into filaments and walls) with empty spaces in between. Exploration of the structure of this web leads to a discussion of dark matter and dark energy, current hot topics in science, probing into the mysteries of our 'Big-Bang' cosmology. An additional comparison of the emerging image of the universe as a whole with the ancient Chinese Buddhist cosmological vision from the Hua-Yen School (Kegon in Japan) again reveals profound parallels. The potential convergence of aspects of subjective, or meditative, explorations with objective scientific constructions is striking and offers links between East and West, as well as potential confirmation of the objective aspects of empathy. © 2017, The Society of Analytical Psychology.

  14. Orbital Picture of Yu-Shiba-Rusinov Multiplets

    Science.gov (United States)

    Heinrich, Benjamin W.; Ruby, Michael; Franke, Katharina J.; Peng, Yang; von Oppen, Felix

    Magnetic impurities on an s-wave superconductor induce Yu-Shiba-Rusinov (YSR) bound states within the excitation gap of the superconductor. Here, we investigate single manganese (Mn) atoms adsorbed on different surface orientations of superconducting lead (Pb) and the nature of their YSR states. Depending on the adsorption site and surface, we detect a distinct number and characteristic patterns of YSR states around the Mn atoms. We show that the YSR states inherit their properties from the Mn d levels, which are split by the surrounding crystal field. The periodicity of the long-range YSR oscillations allows us to identify a dominant coupling of the d states to the outer Fermi sheet of the two-band superconductor Pb. The long-range and directional nature of the states are promising for the design of coupled adatom structures, which could bear topological phases. We acknowledge funding by the Deutsche Forschungsgemeinschaft through Grant No. FR2726/4 and through collaborative research Grants No. Sfb 658, No. CRC 183, and No. SPP 1666, as well as by the European Research Council through Consolidator Grant NanoSpin.

  15. Iodine-131-labelled CDR grafted monoclonal antibody huA33 metastatic colorectal carcinoma: A case study

    International Nuclear Information System (INIS)

    Thomas, D.L.; Lee, F.T.; Scott, A.M.

    1997-01-01

    Full text: A 58-year-old woman was diagnosed with metastatic colorectal carcinoma two years after initial surgery for sigmoid carcinoma. As part of the staging work-up she was initially referred for a 18 F-FDG PET scan at the PET Centre. FDG PET scans of the abdomen and pelvis demonstrated multiple hepatic lesions, but there was no evidence of disease outside the liver. On the basis of extensive hepatic disease, the patient was scheduled for a laparotomy for insertion of an hepatic artery catheter for chemotherapy. In view of her clinical presentation, the patient was eligible for a Phase 1 trial with 131 l-labelled huA33, and agreed to participate. HuA33 is a humanised CDR-grafted recombinant monoclonal antibody directed against an antigen found on >95 per cent of all colorectal carcinomas, and on small bowel and colonic mucosa. The phase 1 trial is a protein dose escalation study designed to examine the biodistribution, pharmacokinetics, dosimetry and safety profile of huA33, and sequential gamma camera images of the whole body were obtained daily until seven days post infusion. SPECT images were obtained on day 6. Excellent localisation of 131 l-huA33 was seen in hepatic lesions. Calculation of whole body retention and tumour uptake was performed, and pharmacokinetic analysis also undertaken. Biopsies of tumour obtained at surgery were used to quantitate tumour uptake and cellular trafficking of 131 l-huA33. On the basis of this phase 1 study, future therapeutic trials of 131 I-huA33 are planned

  16. A Novel Pharmacological Method to Study the Chinese Medicinal Formula Hua-Zheng-Hui-Sheng-Dan

    Directory of Open Access Journals (Sweden)

    Rui Cao

    2015-01-01

    Full Text Available Objectives. Hua-Zheng-Hui-Sheng-Dan (HZHSD was used as an experimental model to explore research methods of large formulae in traditional Chinese medicine (TCM using current molecular biology approaches. Materials and Methods. The trypan blue exclusion assay was used to determine cell viability and cell numbers. Flow cytometry was used to assess cell cycle distribution and apoptosis. The concentration of cyclin D1 was analyzed by enzyme-linked immunosorbent assay. The median effect principle was used in drug combination studies. An orthogonal experimental design was used to estimate the effects of each herb at different concentrations. The HeLa xenograft mouse model was used to compare the antitumor activity of drugs in vivo. Results. Among the 35 herbs that comprise HZHSD, Radix Rehmanniae Preparata (RRP, Caesalpinia sappan (CS, Evodia rutaecarpa (ER, Folium Artemisiae Argyi (FAA, Leonurus japonicus Houtt (LJH, Tumeric (Tu, Radix Paeoniae Alba (RPA, and Trogopterus Dung (TD effectively inhibited the proliferation of HeLa and SKOV3 cells. Only RRR had an effect on HeLa and SKOV3 cell viability. According to the median effect principle, Angelica sinensis (Oliv. (AS, Tabanus (Ta, and Pollen Typhae (PT, which were proven to have a significant synergistic inhibitory effect on the proliferation of HeLa cells, were added to the original eight positive herbs. The combination of RPA and AS had a synergistic effect on inducing cell cycle S phase arrest and decreasing intracellular cyclin D1 in HeLa cells. By orthogonal experimental design, LJH and Tu were considered unnecessary herbs. The small formula (SHZHSD consisted of RPA, AS, RRR, Ta., TD, PT, ER, CS, and FAA and was able to inhibit cell proliferation and induce cell apoptosis. The antitumor effects of HZHSD and SHZHSD were also compared in vivo. Conclusions. Through molecular biology approaches both in vitro and in vivo, research into single drugs, and analysis using the median effect principle

  17. Development and Characterization of a Humanized Anti-HER2 Antibody HuA21 with Potent Anti-Tumor Properties in Breast Cancer Cells

    Directory of Open Access Journals (Sweden)

    Ruilin Li

    2016-04-01

    Full Text Available Human epidermal growth factor receptor 2 (HER2 is one of the most studied tumor-associated antigens for cancer immunotherapy. An engineered anti-HER-2 chimeric A21 antibody (chA21 is a chimeric antibody targeted to subdomain I of the HER2 extracellular domain. Here, we report the anti-tumor activity of the novel engineered monoclonal antibody humanized chA21 (HuA21 that targets HER2 on the basis of chA21, and we describe the underlying mechanisms. Our results reveal that HuA21 markedly inhibits the proliferation and migration of HER2-overexpressing breast cancer cells and causes enhanced antibody-dependent cell-mediated cytotoxicity potency against HER2-overexpressing tumor cells. In particular, HuA21, but not trastuzumab (Tra, markedly suppresses growth and enhances the internalization of the antibody in Tra-resistant BT-474 breast cancer cells. These characteristics are highly associated with the intrinsic ability of HuA21 to down-regulate HER2 activation and inhibit the extracellular signal-regulated kinase 1/2 (ERK1/2 and protein kinase B (Akt signaling pathways. Furthermore, the combination of HuA21 with Tra synergistically enhances the anti-tumor effects in vitro and in vivo and inhibits HER2 activation and the ERK1/2 and Akt signaling pathways. Altogether, our results suggest that HuA21 may represent a unique anti-HER2 antibody with potential as a therapeutic candidate alone or in combination with other anti-HER2 reagents in cancer therapy.

  18. Innovate the Teaching of Taiwaness History: An Application of Multimedia Distance Learning—A Web-site Construction Sample of Shih Hsin University

    Directory of Open Access Journals (Sweden)

    Shaw-Fong Lee

    2004-03-01

    Full Text Available Traditionally, the teaching of history course mostly utilizes face to face instruction and oral presentation. Along with the development of educational technology, the teaching methods could be more various such as using internet and multimedia. Literature reviews also indicate that using internet and multimedia may improve the effect of learning and teaching. This paper explores the development of a web-based instructional system for the course of Taiwanese History at Shih Hsin University.The result and the product of this development project is the web site, http://distance.shu.edu.tw/taiwan/list.htm. The content of the web-site includes instructional materials such as animations, videos, pictures, texts, historical maps, and so on. The developmental methods used in this project use curriculum design, survey, interview, review of literatures and focus group discussion.[Article content in Chinese

  19. Yu Kilchun’s Concept of Reform of the Tax System in the Korean Empire

    Directory of Open Access Journals (Sweden)

    Jinah Yang

    2016-08-01

    Full Text Available Yu Kilchun in “Semubu (Tax Department” criticizes the trend of the tax system, in which the authority to impose and collect taxes had been taken away from the local magistrates and the isŏ class (composed of hyangni, local functionaries, and sŏri, petty clerks during the Kabo Reform was once again returned to them. Yu Kilchun devised a concept of tax system reform on the premise of the reorganization of the administrative districts into the chu-kun-hyang-ri (state-county-district-village system. Yu’s idea was to make myŏn (hyang, district a governing administrative unit, placed under direct government control. To fund the operation of local governments, Yu proposed to create local taxes, chu taxes and hyang. Tax amounts were to be determined by local assemblies, chuhoe and hyanghoe, which were given the authority to deliberate on budget. The authority to review tax sources, levy and collect taxes was given to hyang, a small unit of administrative division. By imbuing this authority to hyang, Yu Kilchun planned to exclude local magistrates and the isŏ class in the tax collection process. Since “Semubu” discusses the reorganization of administrative divisions and local tax administration, as well as local tax system reform, the discovery of this text is significant, as it expands the range of the reform ideas proposed by Yu Kilchun, and furthermore the Enlightenment Party.

  20. YU Ren-cun(郁仁存)——A Famous Oncologist in Integrative Medicine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ YU Ren-cun was born on August 1,1934.After graduating from Jiangxi Medical College in 1955,he took part in the very first Western Doctors' Class for Learning Traditional Chinese Medicine (TCM) held in Beijing from March 1959 to December 1961.Prof.YU systematically learned TCM while taking this class.Since 1962,he has been working in the Beijing Hospital of Traditional Chinese Medicine,eventually being promoted to a Chief Physician by the Beijing Municipal Government in May of 1981.In 1997,Prof.YU was selected as a well-known veteran for the National TCM Doctor Inheritance Work by the State Administration of Traditional Chinese Medicine (SATCM).The State Council of China has awarded him a special subsidy every month for his excellent work.

  1. The life-extension and upgrade program of the Tsing Hua Open-pool Reactor (THOR) and its research prospectives

    International Nuclear Information System (INIS)

    Kai, J.-J.

    1992-01-01

    The Tsing Hua Open-Pool Reactor (THOR) has been operated for thirty years. It is the regulations of the ROCAEC that any reactor shall be decommissioned after forty-year operation since the first fuel loading. Therefore, for extending the lifetime of THOR, it is necessary to have a life-extension program to be approved by the ROCAEC and also completed by the year of 1997. At the same time, for proceeding new research purposes, it is planed to upgrade the thermal power of THOR from 1 Wth up to 3 Wth and hopefully to reach the maximum thermal neutron flux of 5x10 13 n/cm 2 .s and the fast flux close to that order. New research directions involve (a) boron-captured neutron cancer therapy (BNCT) (b) small-angle neutron scattering (SANS). (author)

  2. Spin and pseudospin symmetric Dirac particles in the field of Tietz—Hua potential including Coulomb tensor interaction

    International Nuclear Information System (INIS)

    Ikhdair, Sameer M.; Hamzavi, Majid

    2013-01-01

    Approximate analytical solutions of the Dirac equation for Tietz—Hua (TH) potential including Coulomb-like tensor (CLT) potential with arbitrary spin—orbit quantum number κ are obtained within the Pekeris approximation scheme to deal with the spin—orbit coupling terms κ(κ ± 1)r −2 . Under the exact spin and pseudospin symmetric limitation, bound state energy eigenvalues and associated unnormalized two-component wave functions of the Dirac particle in the field of both attractive and repulsive TH potential with tensor potential are found using the parametric Nikiforov—Uvarov (NU) method. The cases of the Morse oscillator with tensor potential, the generalized Morse oscillator with tensor potential, and the non-relativistic limits have been investigated. (general)

  3. 專論/部落格使用者的資訊行為特徵研究/高世樺;林頌堅 | A Study of Features of Blog Users' Information Behaviors / Shih-Hua Kao; Sung-Chien Lin

    Directory of Open Access Journals (Sweden)

    高世樺、林頌堅

    2008-04-01

    Full Text Available

    部落格已經成為諸多新科技中最具有影響力的媒體之一,並對於使用者的資訊尋求行為造成影響。本研究整理部落格的相關概念及功能,並以二十位部落格使 用者的訪談結果對部落格上的資訊尋求行為特徵進行描述。研究結果顯示,使用者在部落格的開始動機、連結方式、辨別標準、監看與提取方式等等都展現了十分豐 富的行為特徵,研究並發現;(1情感聯繫是受訪者經常提及的使用目標,並且這種動機也影響了各種行為特徵;(2使用者會依照自我的需求以及所處的情境 發展出合適的使用方式,這些新使用方式可能不同於發明者與推廣者所設想的最便於使用的功能;(3部落格上的個人經驗是使用者進行資訊尋求的主要原因之 一;(4豐富而精緻的圖像經常能夠吸引使用者進入部落格。

    Blog has already become one of the most influential media among new technologies, and has impacted on users’ information seeking behaviors. This research  utilized an interview survey to explore related concepts and unique functions of blog media. Interviews with 20 blog users were completed and analyzed to depict characteristics of information seeking behaviors founded in the use of blogs. The result shows that the users had performed a variety of behavioral features in motivations of using blogs, ways of linking from one blog to another, criteria of identification among blogs, methods of blog monitoring and extracting and so forth. Some major observations were also found during the interviews conducted: (1 emotion connection is frequently mentioned by users as one of their main purposes of using blogs, which can be found in each characteristic of information seeking behaviors; (2 when users use new functions of blog, based on their respective needs and situations they can develop their own strategies and methods, which can be very different from those provided or assumed by inventors and promoters; (3 personal experience shared by bloggers is one of the primary reasons why users employ blogs to find information needed; (4 abundant and delicate images embedded in blogs can always attract users’ attention.

    頁次:62-77

  4. Orbital Mechanics near a Rotating Asteroid Yu Jiang1,2,∗ & Hexi ...

    Indian Academy of Sciences (India)

    The Hamilton function can then be written as (Yu & Baoyin 2012a). H = 1. 2 .... The symplectic structure is a differential exterior 2-form defined on a ..... The disadvantage of Poisson-bracket, Poisson and cohomology forms is unavailable for ...

  5. Jing Tong Yu Shu, a traditional Chinese medicine, suppresses IL-1β ...

    African Journals Online (AJOL)

    Zhang et al. 2953. Tropical ... Purpose: To evaluate the effect of a traditional Chinese medicine, Jing Tong Yu Shu (JTYS) on endometriosis in a ..... Flower A, Liu JP, Chen S, Lewith G, Little P. Chinese ... Mol Hum Reprod 2000; 6: 269-275. 18.

  6. Gender Difference in the Interaction Effects of Diabetes and Hypertension on Stroke among the Elderly in the Shih-Pai Study, Taiwan.

    Directory of Open Access Journals (Sweden)

    Yun-Ju Lai

    Full Text Available To investigate the interaction effects of diabetes and hypertension on stroke, and also investigate the independent and interaction effects of parental history and environmental factors on diabetes and hypertension in a cross-sectional elderly population.The Shih-Pai Community Medical Service Program was a community-based, fixed cohort study conducted between June 1999 and November 2002. Socio-demographic and clinical data of subjects aged 65 years and older were collected by well-trained interviewers during home visits. Interaction effects were analyzed using Rothman's synergy index (SI.In total, 4,124 subjects were included in the study, with 2,284 males and 1,840 females. The synergistic interaction of diabetes and hypertension on stroke was statistically significant in women (SI = 3.16, 95% CI: 1.35-7.39. The synergistic interaction of parental diabetes and being overweight on diabetes was only statistically significant in men, and not in women (SI = 3.30, 95% CI: 1.00-10.83 in men, and SI = 1.15, 95% CI: 0.30-4.39 in women.A synergistic interaction was found for diabetes and hypertension in both sexes when parental history and being overweight were combined. Furthermore, combining diabetes and hypertension in elderly women was significant in terms of the risk of stroke. Strategies to control risk factors in individuals at additional high risk are urgently needed.

  7. Fine structures of the ejaculatory sac and sperm pump of the scorpionfly Panorpa liui Hua (Mecoptera: Panorpidae).

    Science.gov (United States)

    Shen, Jian; Hua, Baozhen

    2013-08-01

    Male adults of Panorpidae possess a special sperm pump, through which the males transfer liquid sperm to the females. However, the structures of the sperm pump and the transfer mechanism have not been satisfactorily elucidated hitherto. In this paper the structures of the ejaculatory sac and sperm pump of the scorpionfly Panorpa liui Hua were investigated using light microscopy and scanning electron microscopy. The ejaculatory sac is located between the basal end of the paired vasa deferentia and the aedeagus, comprising a small anterior part and a large posterior part. The anterior part is simple and functions only as a channel for sperm transfer. The epithelial cells of the large posterior part likely have secretory functions. The sperm pump is formed by the posterior region of the ejaculatory sac and derivates of the genital field, which enclose the pumping chamber, a piston and the associated muscles. The orifice of the ejaculatory duct lies ventrad of the piston. The piston of the sperm pump is heavily sclerotized and controlled by two antagonistic muscle pairs. A pair of simple tubular accessory glands opens to the pumping chamber. Two well-developed sex pheromone glands are located on the ventral side of the ejaculatory sac, and are composed of two fan-shaped lamellae. The epithelium of the sex pheromone glands is single-layered, and forms densely filamentous processes. The ejaculation mechanism is briefly discussed based on the morphology of ejaculatory sac and sperm pump. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Comprehensive geological report on Yu Hsien mining area, Yu Hsien coalfield, Hopeh Province in the People's Republic of China

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    This is a detailed geological survey report on Yu Hsien coalfield for the period beginning in 1987 and ending in March, 2001. The survey elucidated the structures, beds, coal seams, coal property, hydro-geological features, and other mining technological conditions in Beiyang Zhuang mining area. In addition, as a result of coal reserves calculation, the total of A, B and C class coal reserves was 328.34 million tons, of which No.1 and No.5 coal seams were 259.79 million tons, taking 79.1% of the entire reserves. The average coal seam thickness of the No.1 and No.5 coal seams, which are the principal minable coal seams, are each 3.10 m and 2.66 m, with the existing depth usually 300-711 m; the coal properties are classified into low-medium ash, low sulfur, low phosphorus, and medium heating value. The coal category is long flame coal, with the use applicable to cement, electric power, gasification, etc. As the infrastructure, Beiyang Zhuang mining area is one of the three mines for which development has been decided in Yu Hsien coalfield. with the planned coal output scheduled for 1.8 million tons, and with a road or a dedicated railroad for coal maintained leading to large and medium cities such as Changkiakow, Suanhwa and Beijing. Further, railway construction is in progress, so that transportation conditions are extremely favorable. Preliminary investigation of industries and construction of coal pits should be considered. (NEDO)

  9. Comparative analysis of the main bioactive components of Xin-Sheng-Hua granule and its single herbs by ultrahigh performance liquid chromatography with tandem mass spectrometry.

    Science.gov (United States)

    Pang, Hanqing; Wang, Jun; Tang, Yuping; Xu, Huiqin; Wu, Liang; Jin, Yi; Zhu, Zhenhua; Guo, Sheng; Shi, Xuqin; Huang, Shengliang; Sun, Dazheng; Duan, Jin-Ao

    2016-11-01

    Xin-Sheng-Hua granule, a representative formula for postpartum hemorrhage, has been used clinically to treat postpartum diseases. Its main bioactive components comprise aromatic acids, phthalides, alkaloids, flavonoids, and gingerols among others. To investigate the changes in main bioactive constituents in its seven single herbs before and after compatibility, a rapid, simple, and sensitive method was developed for comparative analysis of 27 main bioactive components by using ultrahigh-performance liquid chromatography with triple quadrupole electrospray tandem mass spectrometry for the first time. The sufficient separation of 27 target constituents was achieved on a Thermo Scientific Hypersil GOLD column (100 mm × 3 mm, 1.9 μm) within 20 min under the optimized chromatographic conditions. Compared with the theoretical content, the observed content of each analyte showed remarkable differences in Xin-Sheng-Hua granule except thymine, p-coumaric acid, senkyunolide I, senkyunolide H, and ligustilide; the total contents of 27 components increased significantly, and the content variation degrees for the different components were gingerols > flavonoids > aromatic acids > alkaloids > phthalides. The results could provide a good reference for the quality control of Xin-Sheng-Hua granule and might be helpful to interpret the drug interactions based on variation of bioactive components in formulae. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Development of the SONIX software for the YuMO instrument at the IBR-2 reactor

    International Nuclear Information System (INIS)

    Kirilov, A.S.; Litvinenko, E.I.; Astakhova, N.V.; Murashevich, S.M.; Petukhova, T.B.; Yudin, V.E.; Gordelij, V.I.; Islamov, A.Kh.; Kuklin, A.I.

    2003-01-01

    The main results of the modernization of the software complex of the YuMO spectrometer are described. The comparison of the previous MS-DOS based software and new OS-9 based one is carried out. The advantages and disadvantages of each program are described. The main features of the new software complex and the results of its long-term operation are presented. It is shown that the software upgrade essentially improved the spectrometer control. (author)

  11. Qing-Hua Granule induces GLP-1 secretion via bitter taste receptor in db/db mice.

    Science.gov (United States)

    Li, Junyan; Xu, Jie; Hou, Ruifang; Jin, Xin; Wang, Jingyi; Yang, Na; Yang, Li; Liu, Li; Tao, Feng; Lu, Hao

    2017-05-01

    Qing-Hua Granule (QHG), the modified formulation of a classical Chinese prescription named Gegen Qinlian Decoction, was clinically employed to treat type 2 diabetes mellitus (T2DM) through regulation of glucagon-like peptide-1 (GLP-1). However, the potential mechanism is unknown. We investigate whether QHG induces GLP-1 secretion via activation of bitter taste receptor (TAS2R) pathway in the gastrointestinal tract of db/db mice. The db/db mice were intragastrically (i.g.) administered QHG (low/medium/high dose) once daily for 8 weeks. GLP-1 secretion was evaluated. The bitter receptor signaling pathway, which regulates GLP-1 secretion, including TAS2R5 (a subtype of TAS2R), α-gustducin (Gαgust), 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-2 (PLCβ2), transient receptor potential cation channel subfamily M member 5 (TRPM5), was assessed by quantitative real-time polymerase chain reaction (qRT-PCR), Western blot and immunohistochemistry (IHC). The biochemical observations of ileum and pancreas tissue were detected histopathologically. Acquity Ultra Performance LCTM - Micromass ZQ 2000 (UPLC-MS) was used for the phytochemical analysis. QHG exhibited significant and dose-dependent effect on GLP-1 secretion in db/db mice, along with significant up-regulation of TAS2R5 mRNA level and activation of TAS2R pathway (p<0.05). In addition, QHG improved the histopathological structure of ileum and pancreatic tissue. Seventeen compounds were identified in QHG. In conclusion, QHG induces GLP-1 secretion in db/db mice, most likely through the bitter taste receptor pathway. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  12. The Near-Earth Encounter of Asteroid 308635 (2005 YU55): Thermal IR Observations

    Science.gov (United States)

    Lim, Lucy F.; Emery, J. P.; Moskovitz, N. A.; Busch, M. W.; Yang, B.; Granvik, M.

    2012-10-01

    The near-Earth approach (0.00217 AU, or 0.845 lunar distances) of the C-type asteroid 308635 (2005 YU55) in November 2011 presented a rare opportunity for detailed observations of a low-albedo NEA in this size range. As part of a multi-telescope campaign to measure visible and infrared spectra and photometry, we obtained mid-infrared ( 8 to 22 micron) photometry and spectroscopy of 2005 YU55 using Michelle [1] on the Gemini North telescope on UT November 9 and 10, 2011. An extensive radar campaign [2] together with optical lightcurves [3,4] established the rotation state of YU55. In addition, the radar imaging resulted in a shape model for the asteroid, detection of numerous boulders on its surface, and a preliminary estimate of its equatorial diameter at 380 +/- 20 m. In a preliminary analysis, applying the radar and lightcurve-derived parameters to a rough-surface thermophysical model fit to the Gemini/Michelle thermal emission photometry results in a thermal inertia range of approximately 500 to 1500 J m-2 s-1/2 K-1, with the low-thermal-inertia solution corresponding to the small end of the radar size range and vice versa. Updates to these results will be presented and modeling of the thermal contribution to the measured near-infrared spectra from Palomar/Triplespec and IRTF/SpeX will also be discussed. The authors gratefully acknowledge the assistance of observatory staff and the support of the NASA NEOO program (LFL and JPE), the Carnegie fellowship (NAM), and NASA AES, NSF, and the NRAO Jansky Fellowship (MWB). [1] De Buizer, J. and R. Fisher, Proc. Hris (2005), pp. 84-87. [2] Busch, M.W. et al., ACM (2012), abstract #6179. [3] Warner, B., MPBull 39 (2), 84 [4] Pravec, P.

  13. S.Yu. Witte's Customs Policy and Regulation of State Import of Industrial Equipment

    Directory of Open Access Journals (Sweden)

    Антон Юрьевич Петров

    2013-12-01

    Full Text Available The article considers state import of industrial equipment in the context of the customs regulation of Russia’s foreign trade under S.Yu. Witte as the Minister of Finance (1892–1903. The analysis of archival data reveals the motives which drove various ministries of the Russian empire when they gave preference to foreign producers rather than domestic ones. In the 1890s the Ministry of Finance, on the one hand, and other ministries, on the other hand, were debating the necessity of orders for foreign industrial equipment made by the Russian governmental bodies. The article studies the course and results of this interdepartmental struggle.

  14. Antimicrobial and toxicological evaluation of the leaves of Baissea axillaries Hua used in the management of HIV/AIDS patients

    Directory of Open Access Journals (Sweden)

    Agoreyo Freddy O

    2006-06-01

    Full Text Available Abstract Background Persistent diarrhea is a common endemic disease with high incidence among the Africans including Nigerians. It also represents a frequent opportunistic disease in people living with HIV. Diarrhea represents one of the most distressful and persistent symptoms of HIV/AIDS, which may or may not be accompanied by an infection. The leaves decoction of Baissea axillaries Hua (Apocynaceae is used by traditional herbalists in Edo state, Nigeria for the management of people living with HIV/AIDS. Determination of its antimicrobial activity and toxicological profile will provide supportive scientific evidence in favour of its continuous usage. Method Chemical and chromatographic tests were employed in phytochemical investigations. Inhibitory activities of aqueous and ethanolic extracts against clinical strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus faecalis were compared with Togamycin (Spectinomycin. Our report includes minimum inhibitory concentration (MIC against the test organisms. Toxicological evaluation was determined by administering 250 mg/kg and 500 mg/kg of extracts on male Wister rats for 14 days with normal saline as control. The kidneys, liver, heart and testis tissues were examined. Results Phytochemical studies revealed the presence of alkaloids, tannins, and cyanogenetic glycosides. The extracts inhibited the growth of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus to varying extents, but only the ethanolic extract inhibited growth in Streptococcus faecalis. The LD50 of the extract in mice was above 5000 mg/kg body weight when administered intraperitoneally. Toxicological evaluation showed mere ballooning degeneration of the liver at 250 mg/kg while at 500 mg/kg there was tissue necrosis. The low and high doses showed ill-defined leydig cells in the testis and no remarkable changes in the heart and kidneys. Conclusion Extracts of Baissea axillaries have

  15. Correlates of self-report chronic insomnia disorders with 1-6 month and 6-month durations in home-dwelling urban older adults - the Shih-Pai Sleep Study in Taiwan: a cross-sectional community study.

    Science.gov (United States)

    Chiou, Jing-Hui; Chen, Hsi-Chung; Chen, Kuang-Hung; Chou, Pesus

    2016-06-03

    To examine the correlates of insomnia disorder with different durations in home-dwelling older adults. A cross-sectional survey in the Shih-Pai area of Taipei City, Taiwan (The Shih-Pai Sleep Study). A total 4047 subjects over the age of 65 years completed the study (2259 men and 1788 women). The Pittsburgh Sleep Quality Index and the duration of insomnia symptoms were used to identify DSM-IV 1-6 month and 6-month insomnia disorders. The prevalence of DSM-IV defined insomnia disorder was 5.8 %; two-thirds of these case lasted for ≥6 months. The shared correlates for both 1-6 and 6-month insomnia disorders were gender (women), depression and moderate pain. Pulmonary diseases were exclusively associated with 1-6 month insomnia disorder (OR: 2.57, 95 % CI: 1.46-4.52). In contrast, heart disease (OR: 1.73, 95 % CI: 1.21-2.49) and severe pain (OR: 2.34, 95 % CI: 1.14-4.40) were associated with 6-month insomnia disorder. The prevalence of persistent insomnia disorder is higher than short-term insomnia disorder. Correlates for less persistent and more persistent insomnia disorder appears to be partially different. Duration quantifiers may be important in the identification of the etiology of insomnia and further studies with follow-ups are needed to examine the order of developing insomnia disorder and associated conditions.

  16. [Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

    Science.gov (United States)

    Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

    2014-05-01

    Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way.

  17. Comparison of congener profiles of polychlorinated biphenyls between Yu-cheng children and a potential food source

    Energy Technology Data Exchange (ETDEWEB)

    Lung Shih-Chun Candice [Research Center for Environmental Changes, Academia Sinica, Taipei (Taiwan); Guo Yu-Liang Leon; Chang Ho-Yuan [Dept. of Environmental and Occupational Health, Coll. of Medicine, National Cheng Kung Univ., Tainan (Taiwan)

    2004-09-15

    In 1979, about two thousand people in central Taiwan were intoxicated by consumption of the rice oil that was contaminated with polychlorinated biphenyls (PCBs). This ''Yu-cheng'' incident was one of the two human tragedies which people ingested substantial amounts of PCBs within a short period of time. Some of the follow-up epidemiological studies focused on the children born to the exposed mothers, the Yu-cheng children, since they could be exposed to PCBs via breast-feeding or transplacental transfer. This report presents the results of the serum PCB levels of the 21 Yu-cheng children with a congener-specific analysis. On the other hand, fish consumption is thought to be the single most important exposure route to PCBs to the general public; thus, it is crucial to understand PCB exposure from fish consumption. In a separated study to assess PCB contamination in fish, PCB congener concentrations in tilapia (Oreochromis hybrids), the most popular fish in Taiwan, were evaluated. The consumption quantity of tilapia is the highest throughout the Island. It is mostly farmed in fresh water but can also be bred in saltwater. This report presents the concentrations and profiles in the serums of the Yu-cheng children. The congener profile is compared with PCB profile in the serum of Yu-cheng women reported previously and that in one of the potentially significant exposure source, tilapia, conducted in a separated work. Remarkable similarity between the profile of Yu-cheng children and that of the tilapia is revealed and discussed.

  18. La fuerza expresiva del deseo en Lan Yu de Stanley Kwan .

    Directory of Open Access Journals (Sweden)

    David L. Eng

    2007-12-01

    Full Text Available Stanley Kwan's Lan Yu configures the emergence of homosexuality in contemporary China far beyond its validation in recognizably Western identitarian terms: the affirmation of an existing but misrecognized minority population; the defense of sexual "perversion"; the positing of sexual freedom, legal recognition, and political rights; the justification of a bourgeois consumer lifestyle, or even the expression of a universalizing and bindingtove bringing togethertwo abstract individuáis. Instead, in Kwan's film, homosexuality and its expressive desire mark the emergence of a new humanism in (postsocialist China under the shadows of global capitalism and neoliberal development. Gays and lesbians, that is, are harbingers of a new modernity, helping to situate China in its proper place within a cosmopolitan globalized world. From this perspective, homosexuality functions as a critical tool for organizing and evaluating the historical continuities and ruptures among China's (semicolonial past, its revolutionary aspirations for a socialist modernity, and its present investments in a neoliberal capitalist world order.

  19. Formation of the oil composition of the Yu0 Bazhenov formation, Salym oil field

    Directory of Open Access Journals (Sweden)

    E.V. Soboleva

    2017-05-01

    Full Text Available The Bazhenov horizon of Western Siberia has been studied in considerable detail from different perspectives and different methods, a large number of studies have been devoted to a wide range of issues related to the lithological composition of rocks, their reservoir properties, the study of organic matter, properties and composition of oil at various analytical levels, and many others. This work is devoted to restoring conditions for the formation of oil properties and composition of the Yu0 Salym oil field, based mainly on the geochemical aspects of the study of oil changes both in area and in the section within the productive layer of Salym structure, using some geological data, such as structural plan for the reflecting horizon B (the roof of the Bazhenov formation, having a complex configuration, reservoir temperatures and pressure, well flow rates, and others. There is no single reservoir at the Salym field in the Yu0 formation. For the conclusions of the geological-geochemical interpretation, a sampling of 61 samples of oil from exploration, appraisal and production wells of the initial stages of production was used, since in the future when oil is extracted, the ecology in the deposits changes, and 21 samples of oil from other fields in the West Siberian oil and gas basin. Conventionally, three types of oils are distinguished, differing in their physicochemical parameters, group hydrocarbon and molecular composition. It was suggested that in addition to the own organic matter of the Bazhenov formation, hydrocarbon fluids of the Vasyugan, Tyumen formations and possibly Paleozoic rocks were involved in the formation of the oil composition. The flow of light liquid hydrocarbons and gases occurred along the zones of faults of different genesis and duration of existence.

  20. PREFACE: SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor: Devoted to the 75th anniversary of Yu M Ostanevich's birth

    Science.gov (United States)

    Gordely, Valentin; Kuklin, Alexander; Balasoiu, Maria

    2012-03-01

    The Second International Workshop 'SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor', devoted to the 75th anniversary of the birth of Professor Yu M Ostanevich (1936-1992), an outstanding neutron physicist and the founder of small-angle neutron scattering (field, group, and instrument) at JINR FLNPh, was held on 27-30 May at the Frank Laboratory of Neutron Physics. The first Workshop was held in October 2006. Research groups from different neutron centers, universities and research institutes across Europe presented more than 35 oral and poster presentations describing scientific and methodological results. Most of them were obtained with the help of the YuMO instrument before the IBR-2 shutdown in 2006. For the last four years the IBR-2 reactor has been shut down for refurbishment. At the end of 2010 the physical launch of the IBR-2M reactor was finally realized. Nowadays the small-angle neutron scattering (SANS) technique is applied to a wide range of scientific problems in condensed matter, soft condensed matter, biology and nanotechnology, and despite the fact that there are currently over 30 SANS instruments in operation worldwide at both reactor and spallation sources, the demand for beam-time is considerably higher than the time available. It must be remembered, however, that as the first SANS machine on a steady-state reactor was constructed at the Institute Laue Langevin, Grenoble, the first SANS instrument on a 'white' neutron pulsed beam was accomplished at the Joint Institute for Nuclear Research at the IBR-30 reactor, beamline N5. During the meeting Yu M Ostanevich's determinative and crucial contribution to the construction of spectrometers at the IBR-2 high-pulsed reactor was presented, as well as his contribution to the development of the time-of-flight (TOF) small-angle scattering technique, and a selection of other scientific areas. His leadership and outstanding scientific achievements in applications of the

  1. Teachers' Use of a Pedagogical Framework for Improvement in Mathematics Teaching: Case Studies from YuMi Deadly Maths

    Science.gov (United States)

    Carter, Merilyn; Cooper, Tom; Anderson, Robyn

    2016-01-01

    This paper describes the pedagogical framework used by YuMi Deadly Maths, a school change process used to improve mathematics teaching and thus enhance employment and life chances for socially disadvantaged students. The framework, called the RAMR cycle, is capable of being used by mathematics teachers for planning and delivering lessons and units…

  2. Serum concentrations and profiles of polychlorinated biphenyls in Taiwan Yu-cheng victims twenty years after the incident

    Energy Technology Data Exchange (ETDEWEB)

    Lung, S.-C. Candice [Research Center for Environmental Changes, Academia Sinica, Nankang, Taipei, Taiwan 115 (China); Guo, Y.-L.L. [Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Rd., Tainan, Taiwan 70428 (China); Chang, H.-Y.[Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Rd., Tainan, Taiwan 70428 (China)]. E-mail: h7154@mail.ncku.edu.tw

    2005-07-15

    In 1979, about 2000 people in central Taiwan were intoxicated via rice oil consumption that was contaminated with polychlorinated biphenyls (PCBs). This 'Yu-cheng' incident was one of the two known major human PCB intoxication episodes. Twenty years after the intoxication, serum samples of 435 Yu-cheng victims, 414 adults and 21 children, were collected. Sixteen PCB congeners were analyzed with a gas chromatograph-electron capture detector. We found the median concentration of total PCBs in the adult serum was 1500 ng/g lipid, still substantially higher than that of the general population in Taiwan (3.7-fold) and most seafood consumers in the world. Most of analyzed PCB congeners in children were below or around the detection limits. Congener no. 138, however, had the highest concentrations, approximately accounting for 55% and 29% in the child and adult groups, respectively. Given that PCBs are persistent organic pollutants and endocrine disruptors, the concentrations and congener-specific profiles regarding the Yu-cheng victims provide valuable information for the investigation of such chemicals in humans. - Total serum PCBs in the Yu-cheng adult victims twenty years after the incident were still higher than that of the general population in Taiwan.

  3. Binding energy of donor impurity states and optical absorption in the Tietz-Hua quantum well under an applied electric field

    Science.gov (United States)

    Al, E. B.; Kasapoglu, E.; Sakiroglu, S.; Duque, C. A.; Sökmen, I.

    2018-04-01

    For a quantum well which has the Tietz-Hua potential, the ground and some excited donor impurity binding energies and the total absorption coefficients, including linear and third order nonlinear terms for the transitions between the related impurity states with respect to the structure parameters and the impurity position as well as the electric field strength are investigated. The binding energies were obtained using the effective-mass approximation within a variational scheme and the optical transitions between any two impurity states were calculated by using the density matrix formalism and the perturbation expansion method. Our results show that the effects of the electric field and the structure parameters on the optical transitions are more pronounced. So we can adjust the red or blue shift in the peak position of the absorption coefficient by changing the strength of the electric field as well as the structure parameters.

  4. Fractionated BNCT for locally recurrent head and neck cancer: Experience from a phase I/II clinical trial at Tsing Hua Open-Pool Reactor

    International Nuclear Information System (INIS)

    Wang, Ling-Wei; Chen, Yi-Wei; Ho, Ching-Yin; Hsueh Liu, Yen-Wan; Chou, Fong-In; Liu, Yuan-Hao; Liu, Hong-Ming; Peir, Jinn-Jer; Jiang, Shiang-Huei; Chang, Chi-Wei; Liu, Ching-Sheng; Wang, Shyh-Jen; Chu, Pen-Yuan; Yen, Sang-Hue

    2014-01-01

    To introduce our experience of treating locally and regionally recurrent head and neck cancer patients with BNCT at Tsing Hua Open-Pool Reactor in Taiwan, 12 patients (M/F=10/2, median age 55.5 Y/O) were enrolled and 11 received two fractions of treatment. Fractionated BNCT at 30-day interval with adaptive planning according to changed T/N ratios was feasible, effective and safe for selected recurrent head and neck cancer in this trial. - Highlights: • We treated 12 patients with recurrent Head and Neck (H and N) cancer after radical surgery and radiotherapy since 2010. • Four complete response (CR) and 3 partial response (PR) were found. Total response rate was 58%. • Two patients had local control longer than one year. • No grade 4 or higher toxicity was noted for both acute and chronic effects

  5. The genome and structural proteome of YuA, a new Pseudomonas aeruginosa phage resembling M6.

    Science.gov (United States)

    Ceyssens, Pieter-Jan; Mesyanzhinov, Vadim; Sykilinda, Nina; Briers, Yves; Roucourt, Bart; Lavigne, Rob; Robben, Johan; Domashin, Artem; Miroshnikov, Konstantin; Volckaert, Guido; Hertveldt, Kirsten

    2008-02-01

    Pseudomonas aeruginosa phage YuA (Siphoviridae) was isolated from a pond near Moscow, Russia. It has an elongated head, encapsulating a circularly permuted genome of 58,663 bp, and a flexible, noncontractile tail, which is terminally and subterminally decorated with short fibers. The YuA genome is neither Mu- nor lambda-like and encodes 78 gene products that cluster in three major regions involved in (i) DNA metabolism and replication, (ii) host interaction, and (iii) phage particle formation and host lysis. At the protein level, YuA displays significant homology with phages M6, phiJL001, 73, B3, DMS3, and D3112. Eighteen YuA proteins were identified as part of the phage particle by mass spectrometry analysis. Five different bacterial promoters were experimentally identified using a promoter trap assay, three of which have a sigma54-specific binding site and regulate transcription in the genome region involved in phage particle formation and host lysis. The dependency of these promoters on the host sigma54 factor was confirmed by analysis of an rpoN mutant strain of P. aeruginosa PAO1. At the DNA level, YuA is 91% identical to the recently (July 2007) annotated phage M6 of the Lindberg typing set. Despite this level of DNA homology throughout the genome, both phages combined have 15 unique genes that do not occur in the other phage. The genome organization of both phages differs substantially from those of the other known Pseudomonas-infecting Siphoviridae, delineating them as a distinct genus within this family.

  6. Maps of Relocation and Poems of Tang Dynasty Poets: Li Bai, Du Fu, and Han Yu

    Directory of Open Access Journals (Sweden)

    羅鳳珠、白璧玲、廖泫銘、范毅軍 、鄭錦全 Feng-Ju Lo,Pi-Ling Pai,Hsiung-Ming Liao,I-Chun Fan,Chin-Chuan Cheng

    2014-04-01

    Full Text Available Geographic environments affect literary contents and genre and thus, since ancient times, geographical area has been used to classify Chinese literature. In 1936 Liang Qichao was keenly aware of the relationship between literature and geography and brought up the idea of “literarygeography”. In 1979 Professor Chen Zhengxiang produced maps of birthplaces of Tang and Song poets to show the shift of Chinese cultural center from north to south. Furthermore, in the pastdecade, the attention to research in literary geography and geographical distribution of writersgradually increased. However, most studies focused on geographical distribution of birthplaces of writers and very few focused on the relationship between poets’ journey and the contents of their writings and their geographic environment. Meanwhile, geographic information system and aerialphotography have developed quickly and have become useful tools for the study of literary geography.Since then, the academic circles in Taiwan have built a solid foundation in this area. While Li Baiand Du Fu were called poetic immortal and poetic sage of the middle and end periods of the heydayof Tang Dynasty, respectively, Han Yu advocated the classical Chinese movement and becameone of the eight great authors of Tang and Song dynasties. Han Yu was also the best representative of Middle Tang poets. While the styles of these three poets differed from each other, they held key positions in the development and evolution of Tang poetry. Their footprints spread all over the countryand greatly affected later developments and contemporary of poetry. This project makes use of the digital Tang Dynasty maps by Tan Qixiang, Tang Dynasty transportation route maps by Yan Gengwang,aerial maps, the All Tang Poems, and chronicles of the poets to build the three poets’ relocation maps and study their poetic literature, language, geography, and interactions with others, in hopesof opening a new research direction

  7. Fabrication of welded pipes of the KhN45Yu alloy

    International Nuclear Information System (INIS)

    Lyapunov, A.I.; Krichevskij, E.M.; L'vov, V.N.; Kozlov, N.N.; Kireeva, T.S.

    1977-01-01

    A highly heat-resistant KhN45Yu (EP 747) alloy has been developed; the alloy is designed to withstand prolonged service in the temperature range of 1000-1300 deg C, or short-term service at 1300-1400 deg C. The satisfactory ductility and good weldability of the alloy have made it possible to obtain sheets and pipes (32 x 2.0 mm) by argon arc welding. The ductility of pipes from EP 747 alloy exceeds that of pipes from KhN78T (EI 435) alloy by 5.10%, the strength being approximately equal. In regard to strength the welded joint differs little from the base metal. The ductility characteristics up to 900 deg C are also equal, since failure occurs in the base metal. At higher temperatures the welded joint fails in the metal of the weld, and its ductility drops sharply. The grain size of the base metal corresponds to No. 3-4. The welded joint has a cast structure with a grain size larger than No. 1, but its ductility characteristics are satisfactory. This structure ensures an increased long-term strength of the material at 1000-1200 deg C

  8. Kondo Effect of U Impurities in Dilute (YU)2Zn17

    Science.gov (United States)

    Takagi, Shigeru; Suzuki, Hiroyuki; Anzai, Kousuke

    2001-10-01

    Extending previous work on single-site properties of U ions in (LaU)2Zn17, we have investigated, from ρ(T), χ(T) and Cp(T) on single crystals, (Y1-xUx)2Zn17 with x=0.025 and 0.050, which has almost the same unit-cell volume as an antiferromagnetic heavy-electron compound U2Zn17. Remarkable features in the dilute-impurity limit have been clarified, which include Kondo behavior of ρ(T), large and almost isotropic χimp(T), and strongly enhanced Cimp(T)/T with gigantic γimp=2.02 2.05 J/K2·mole-U as T→0 due to a low characteristic energy-scale of the system. It is shown that gross features of the data are explained in terms of the conventional Kondo effect in the presence of the crystal field with the U3+ \\varGamma6 doublet ground state. It is also shown that the variation of γ with the unit-cell volume in related systems is not explained as a volume effect on TK and that even the behavior of fictitious “paramagnetic” U2Zn17 is not described as a collection of U impurities in dilute (YU)2Zn17.

  9. FY 1999 Report on overseas geological structure surveys. Joint Japan-China Yu Xian exploitation project; 1999 nendo kaigai chishitsu kozo nado chosa hokokusho. Nippon Chugoku sekitan kyodo tansa Yu Xian project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This project is based on the (agreement of the joint exploitation project for Yu Xian block in Yu Xian coal mine, Province of Hepei by Japan's NEDO and China's Coal Geological Bureau), signed on October 4, 1996. The joint project mainly comprises seismic exploitation and test drilling, Japan being mainly responsible for the former and China for the latter. The final report will be drawn jointly for the geological survey results necessary for designing coal mines. The Yu Xian block contains the Jurassic coal seams, which are covered by the Quaternary bed and not exposed to the surface. The Quaternary bed base is 50 to 400 m deep from the surface, and coal seams are 300 to 700 m deep also from the surface. A total of 11 coal seams are located in the Xiahuayuan strata as the coal-bearing strata. The first and fifth seams are most promising ones. In particular, the fifth seam is thick (0.2 to 6.91 m thick) and distributed throughout the block. It is estimated that 8 coal seams have a total coal quantity of approximately 346 million tons. (NEDO)

  10. Language Personality of the Publicist: Rhetorical and Stylistic Canon (Yu. Senkevich “To “Ra” Across the Atlantic”

    Directory of Open Access Journals (Sweden)

    Olga V. Shatalova

    2017-10-01

    Full Text Available In article the communicative and linguistic parameters of the speech of the publicist of the XX century Yu. Senkevich which are declared as a sample for formation of the language personality in the conditions of development of the modern information and communicative environment are designated. On the example of the analysis of the book «On “Ra” through Atlantic» locates the fact of that Yu.N. Senkevich’s creativity corresponds to the main criteria of popular scientific journalism: high degree of reliability, authoritativeness of the publicist; dynamism, dramatic nature, intelligence of a statement. The unostentatious enlightenment based on updating of scientific knowledge for the addressee and a dialogization of a publicistic discourse, the high level of psychological and philosophical generality, the declaration of humanistic values form specific rhetoric which is supported by the formal and grammatical organization of the speech of the publicist. Priority of syntactic designs of a certain type, stylistic ladders and figures – dynamism of a statement and scale of representation of material define. The humour and easy self-irony as significant characteristics of the language personality define a basis of the rhetorical and stylistic canon realized in publicistic works Yu.N. Senkevich – «the human view of people and society» that in the modern information and communicative environment becomes a necessary reference point.

  11. M.Yu. Lermontov’s linguistic/literary personality through perspective of linguistic personality perception by philologist V.V. Vinogrado

    Directory of Open Access Journals (Sweden)

    Larisa N. Kuznetsova

    2011-04-01

    Full Text Available The article considers M.Yu. Lermontov’s linguistic / literary personality through perspective of linguistic personality perception by Great Russian scientist-philologist and linguist, Academician V.V. Vinogradov.

  12. INCUBATORS WITHIN UNIVERSITY AND CLUSTERED CONTEXTS: CASES OF NATIONAL CHIAO TUNG UNIVERSITY (NCTU AND NATIONAL TSING HUA UNIVERSITY (NTHU INCUBATORS IN HSINCHU, TAIWAN

    Directory of Open Access Journals (Sweden)

    Khairul Akmaliah Adham

    2008-01-01

    Full Text Available Research literature on business incubators has highlighted the significance of clustered locational contexts and networking as key to an incubator's success. Using the case study approach, this study aimed to test the validity of this framework for explaining the level of success of the National Chiao Tung University (NCTU and National Tsing Hua University (NTHU Incubators in Hsinchu, Taiwan – both of which are highly-networked, cluster-centric and university-based. In-depth interviews were conducted with the managers of both incubators, and these were followed by information gathering on university patents and knowledge transfers from the research and development (R&D office at each university. Analysis found that the incubators' locational contexts determined the degree and manner of their networking, but their profitability and growth potential were influenced by many other factors working in combination. Satisfying their sponsors' requirements and serving their core functions through sound management and strategic planning appeared to be the key to achieving profitability and sustainability, with benefits for all stakeholders. These constructs provide directions for more research on the performance of incubators and other business entities that are located within university and clustered contexts.

  13. Explicit and exact nontraveling wave solutions of the (3+1)-dimensional potential Yu-Toda-Sasa-Fukuyama equation

    Science.gov (United States)

    Yuan, Na

    2018-04-01

    With the aid of the symbolic computation, we present an improved ( G ‧ / G ) -expansion method, which can be applied to seek more types of exact solutions for certain nonlinear evolution equations. In illustration, we choose the (3 + 1)-dimensional potential Yu-Toda-Sasa-Fukuyama equation to demonstrate the validity and advantages of the method. As a result, abundant explicit and exact nontraveling wave solutions are obtained including two solitary waves solutions, nontraveling wave solutions and dromion soliton solutions. Some particular localized excitations and the interactions between two solitary waves are researched. The method can be also applied to other nonlinear partial differential equations.

  14. Supercavitation Advances and Perspectives A collection dedicated to the 70th jubilee of YuN Savchenko

    CERN Document Server

    2012-01-01

    This collection is dedicated to the 70th jubilee of Yu. N. Savchenko, and presents experimental, theoretical, and numerical investigations written by an international group of well-known authors. The contributions solve very important problems of the high-speed hydrodynamics, such as supersonic motion in water, drag diminishing, dynamics and stability of supercavitating vehicles, water entry and hydrodynamic performances of hydrofoils, ventilated cavities after a disc and under the ship bottom. The  book is written for researches, scientists, engineers, and students interested in problems of hydromechanics.

  15. FY 2000 report on the survey of the overseas geological structure. Japan-China joint coal exploration - Yu Xian project; 2000 nendo kaigai chishitsu kozo nado chosa hokokusho. Nippon Chugoku sekitan kyodo tansa Yu Xian project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The geological survey was carried out which is needed for coal mine design in the Yu Xian coal mine area, Yu Xian coal field, Hebei province, China. The term of survey was 5 years from 1996 to 2000. Activities are mainly for seismic survey and boring survey. Japan was in charge of the seismic survey, and China in charge of the boring survey. Both attained the goal. The results of the activities were summed up in the following 7 items: 1) outline of the survey; 2) general investigation; 3) state of the exploration related materials/machinery; 4) field survey; 5) items of survey; 6) results of the survey; 7) conclusion. In 6), the geological analysis, coal quality survey and coal amount survey were conducted. In the geological analysis, analyzed were the succession of strata, geological structure, and the situation of existence of coal seams. In 7), the following were made clear: geological structure of the survey area, coal seam, coal quality, hydrological geology, other conditions of drilling technology, and coal amount. The coal amount was 328.34 million tons in a total of A/B/C class coals. The total coal amount of Nos. 1 and 5 coal seams was 259.79 million tons, which was 79.1% of the total coal amount in all area. The average thickness of Nos. 1 and 5 coal seams, which are the main minable coal seams, was 3.10m and 2.66m, respectively. (NEDO)

  16. Yuánmíng Yuán en el siglo XVIII: Arte entre la diplomacia y la filosofía; entre Europa y Pekín

    Directory of Open Access Journals (Sweden)

    Pedro Luengo

    2016-01-01

    Full Text Available Este estudio pretende probar que el Yuánmíng Yuán fue diseñado como una representación del macrocosmos imperial a partir de la filosofía de la China de Qianlong. Para ello se valorará la función simbólica de los palacios de estilo europeo a partir de las descripciones de embajadas orientales y occidentales. Esta información se pondrá en relación con las diferentes representaciones pictóricas del jardín, conservadas tanto en grabados o acuarelas como en pinturas murales. A partir de toda esta información se pretende valorar su utilización en las visitas de diferentes legados diplomáticos extranjeros. En concreto, se intenta comprobar que los palacios europeos se utilizaron eminentemente para impresionar a las misiones orientales, y no tanto a las occidentales.

  17. Comparatively evaluating the pharmacokinetic of fifteen constituents in normal and blood deficiency rats after oral administration of Xin-Sheng-Hua Granule by UPLC-MS/MS.

    Science.gov (United States)

    Pang, Han-Qing; Tang, Yu-Ping; Cao, Yu-Jie; Tan, Ya-Jie; Jin, Yi; Shi, Xu-Qin; Huang, Sheng-Liang; Sun, Da-Zheng; Sun, Jin; Tang, Zhi-Shu; Duan, Jin-Ao

    2017-09-01

    Xin-Sheng-Hua Granule (XSHG), a famous traditional Chinese medicine prescription, are clinically applied for the treatment of postpartum disease through nourishing blood and promoting blood circulation. In this investigation, a multi-constituents (trigonelline, stachydrine hydrochloride, hydroxysafflor yellow A, chlorogenic acid, amygdalin, leonurine, liquiritin, ferulic acid, senkyunolide I, senkyunolide H, glycyrrhizic acid, senkyunolide A, ligustilide, butylidenephthalide and glycyrrhetinic acid) pharmacokinetic study of XSHG was conducted for the first time. These fifteen constituents in both normal and blood deficiency rat plasma were monitored by using the established and validated ultra-high-performance liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry (UPLC-TQ-MS/MS) method. The samples were prepared through removing protein from plasma with three volumes of methanol. Sufficient separation of target constituents and internal standards (chloramphenicol and clarithromycin) was obtained on a Thermo Scientific Hypersil GOLD column (100mm×3mm, 1.9μm) within a 20min gradient elution (0.1% formic acid aqueous - acetonitrile). Multiple reaction monitoring (MRM) mode was applied to monitor target analytes in both positive and negative electrospray ionization. For the fifteen selected target analytes, this method was fully validated with excellent linearity (r≥0.9925), satisfactory intra- and inter-day precisions (RSD≤11.87%), as well as good accuracies (RE, between -12.84 and 11.69). And the stabilities, matrix effects and extraction recoveries of the rat plasma samples were also within acceptable limits (RSD<15%). Compared to normal group, the pharmacokinetics of major active constituents (except liquiritin and glycyrrhetinic acid) had significant differences (P<0.05) in the model rats, indicated that several metabolite enzymes activities could be altered at disease condition. Copyright © 2017 Elsevier B.V. All

  18. Review on the Book: Pochekaev R.Yu. The Golden Horde Law (Kazan, 2009. 260 p. » 231

    Directory of Open Access Journals (Sweden)

    E.G. Sayfetdinova

    2015-06-01

    Full Text Available This paper contains a review of the R.Yu. Pochekaev’s book “The Golden Horde Law”. The reviewer points out that the Pochekaev’s book is a significant academic research in both the study of the Golden Horde history and the law system of the Eurasian Turkic-Mongol peoples. This book is published by the Center for Research on the Golden Horde Civilization at the Sh.Marjani Institute of History of the Academy of Sciences of the Republic of Tatarstan. For several years, the author of this book, R.Yu. Pochekaev, has been concerned with the the history of the Golden Horde State and its law system. He has published a number of works on this topic, the main conclusions of which are reflected in this generalizing work. The study is based on a wide range of sources (annals and chronicles, memoirs of contemporaries, bureaucratic and numismatic materials and numerous studies including the works of foreign specialists in the original language. In his book, the author organically combines the latest achievements of research on both the Golden Horde history and theory and history of law. The book will be of interest to experts of the Golden Horde history and Orientalists, who are often faced with the legal aspects of the material under study.

  19. Study on a Dynamic Vegetation Model for Simulating Land Surface Flux Exchanges at Lien-Hua-Chih Flux Observation Site in Taiwan

    Science.gov (United States)

    Yeh, T. Y.; Li, M. H.; Chen, Y. Y.; Ryder, J.; McGrath, M.; Otto, J.; Naudts, K.; Luyssaert, S.; MacBean, N.; Bastrikov, V.

    2016-12-01

    Dynamic vegetation model ORCHIDEE (Organizing Carbon and Hydrology In Dynamic EcosystEms) is a state of art land surface component of the IPSL (Institute Pierre Simon Laplace) Earth System Model. It has been used world-wide to investigate variations of water, carbon, and energy exchanges between the land surface and the atmosphere. In this study we assessed the applicability of using ORCHIDEE-CAN, a new feature with 3-D CANopy structure (Naudts et al., 2015; Ryder et al., 2016), to simulate surface fluxes measured at tower-based eddy covariance fluxes at the Lien-Hua-Chih experimental watershed in Taiwan. The atmospheric forcing including radiation, air temperature, wind speed, and the dynamics of vertical canopy structure for driving the model were obtained from the observations site. Suitable combinations of default plant function types were examined to meet in-situ observations of soil moisture and leaf area index from 2009 to 2013. The simulated top layer soil moisture was ranging from 0.1 to 0.4 and total leaf area was ranging from 2.2 to 4.4, respectively. A sensitivity analysis was performed to investigate the sensitive of model parameters and model skills of ORCHIDEE-CAN on capturing seasonal variations of surface fluxes. The most sensitive parameters were suggested and calibrated by an automatic data assimilation tool ORCHDAS (ORCHIDEE Data Assimilation Systems; http://orchidas.lsce.ipsl.fr/). Latent heat, sensible heat, and carbon fluxes simulated by the model were compared with long-term observations at the site. ORCHIDEE-CAN by making use of calibrated surface parameters was used to study variations of land-atmosphere interactions on a variety of temporal scale in associations with changes in both land and atmospheric conditions. Ref: Naudts, K., et al.,: A vertically discretised canopy description for ORCHIDEE (SVN r2290) and the modifications to the energy, water and carbon fluxes, Geoscientific Model Development, 8, 2035-2065, doi:10.5194/gmd-8

  20. Promoting increased Chlorella sorokiniana Shih. et Krauss ...

    African Journals Online (AJOL)

    Prof. Nweze

    2014-12-31

    Dec 31, 2014 ... Also, the extract obtained from the leaves of Moringa in 80% ethanol contains growth enhancing principles for higher plants. (Makkar and Becker, 1996). In view of the fact that. Chlorella biomass is much sought after for use as health food supplement and for biofuels among other uses, enhanced production ...

  1. Transcriptomic Profiling Reveals Complex Molecular Regulation in Cotton Genic Male Sterile Mutant Yu98-8A.

    Directory of Open Access Journals (Sweden)

    Weiping Fang

    Full Text Available Although cotton genic male sterility (GMS plays an important role in the utilization of hybrid vigor, its precise molecular mechanism remains unclear. To characterize the molecular events of pollen abortion, transcriptome analysis, combined with histological observations, was conducted in the cotton GMS line, Yu98-8A. A total of 2,412 genes were identified as significant differentially expressed genes (DEGs before and during the critical pollen abortion stages. Bioinformatics and biochemical analysis showed that the DEGs mainly associated with sugars and starch metabolism, oxidative phosphorylation, and plant endogenous hormones play a critical and complicated role in pollen abortion. These findings extend a better understanding of the molecular events involved in the regulation of pollen abortion in genic male sterile cotton, which may provide a foundation for further research studies on cotton heterosis breeding.

  2. III International Conference on Small Angle Neutron Scattering dedicated to the 80 anniversary of Yu.M. Ostanevich

    International Nuclear Information System (INIS)

    2017-01-01

    Preface “Among the many well-known fundamental and applied consequences of neutron discovery, one of the first was the emergence of structural neutron diffraction - one of the methods for studying the spatial structure of condensed matter at the atomic level. Investigating the dynamics of biological macromolecules by neutron diffraction methods is an area that is almost untouched. We believe that also in this direction one should expect rapid progress.” Yu.M.Ostanevich and I.N.Serdyuk Uspekhi Fizicheskih Nauk (1982) More than 30 years after Ostanevich and Serdyuk reviewed the then 50 years from the neutron discovery, we are happy to support their statement and prediction by reporting on the further progress in the field of neutron scattering research. Frank Laboratory of Neutron Physics has organized the III International Conference on Small Angle Neutron Scattering (YuMO2016) that was – not coincidently – dedicated to the 80th anniversary of Ostanevich. Yuriy Mechislavovich Ostanevich (1936–1992) has had a determinative and crucial contribution to the construction of spectrometers at the pulsed reactor IBR in Dubna, Russia. He contributed in particular to the development of time-of-flight small-angle neutron scattering (SANS) technique, and the selection of advanced scientific areas for its application. The SANS instrument at the IBR-2 reactor is called YuMO in his honour. The Ostanevich’s leadership and outstanding scientific achievements in SANS studies of polyelectrolytes, small molecules, fractals, metallic glasses, macromolecules, polymers, etc., were recognized also by a number of awards including the State Prize of the Russian Federation in 2000. To this end of course, we should not forget mentioning the contribution of close collaborators of Ostanevich: Laszlo Cser, Josef Plestil as well as Alexander Kunchenko, Vadim Bezzabotnov and Nikolay Gorski. The YuMO2016 conference focused on providing opportunities to discuss various possibilities of

  3. FY 2000 survey of the geological structure overseas, etc. Japan-China joint coal exploration - Yu Xian project; 2000 nendo kaigai chishitsu kozo nado chosa - futai shiryoshu. Nippon Chugoku sekitan kyodo tansa Yu Xian project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    This data book summarized the proceedings and the technical report of the management committee on the Japan-China geological structure survey based on the consultation concluded between NEDO and China's bureau of coal field geology and a report meeting on the Yu Xian project. In the exploration, conducted were the boring survey of 10 boreholes, seismic survey of 2D (71 traverse lines, 180.105km) and 3D (1.5km{sup 2}), VSP (6 holes (345 shots)) and the low velocity band survey (2,072 shots). The geological structure of the area presented the syncline structure with a gentle line associated with foldings and a number of faults and was classified into the medium class or the class of a little complication in the Chinese standard. The number of the faults confirmed in this exploration totaled 57. Coal reserves by coal seam were 157.22 million tons at No. 5 seam and 102.57 million tons at No. 1 seam. The total amount of the two seams was 79.1% of the total coal amount in all area. The coal quality of Nos. 1 and 5 was brown coal - flame coal in the Chinese classification, and subbituminous coal B - subbituminous coal C in the ASTM classification. The coal, however, cannot be used for process raw coal. There is a technical potentiality of the fixed bed pressurized gasification. (NEDO)

  4. Real space mapping of Yu-Shiba-Rusinov states of an extended magnetic scatterer on a conventional superconductor

    Energy Technology Data Exchange (ETDEWEB)

    Etzkorn, Markus; Eltschka, Matthias; Jaeck, Berthold; Topp, Andreas; Ast, Christian R. [Max-Planck-Institute for Solid State Research, 70569 Stuttgart (Germany); Kern, Klaus [Max-Planck-Institute for Solid State Research, 70569 Stuttgart (Germany); Ecole Polytechnique Federale de Lausanne, 1015 Lausanne (Switzerland)

    2016-07-01

    The interaction of a local magnetic impurity with a superconductor causes the formation of Yu-Shiba-Rusinov (YSR)states in the vicinity of the impurity. These have recently received increasing attention in the context of Majorana Fermions and other exotic states that might be created from the mutual interplay. YSR states have been extensively studied by scanning tunneling microscopy and so far have been discussed mainly in the limit of point scattering impurities. Here we present our investigations of the local properties of single magnetic Copper-Phthalocynane molecules on the (5x1) reconstructed, superconducting V(100) surface measured at 15 mK temperature. We find very intense YSR states with energies that depend on the precise absorbtion geometry of the molecule. At the same time we find no indication of a local suppression of the superconducting gap around the impurity. We follow the state evolution in real space for about 3 nm corresponding to about three orders of magnitude in spectral intensity. The spectra display rich structure with local variations in the electron-hole asymmetries. The observed intensity changes in the spectra can not be described on the basis of a single point like scattering potential.

  5. BOOKPLATES, OWNERS’ RECORDINGS AND DEDICATORY INSCRIPTIONS ON THE BOOKS FROM THE BOOK COLLECTION OF THE MATHEMATICIAN I. YU. TIMTCHENKO

    Directory of Open Access Journals (Sweden)

    О. В. Полевщикова

    2015-09-01

    Full Text Available The professor of Novorossiysky (Odessa University I. Yu. Timchenko (1863-1939 managed to collect a remarkable library on the history of Mathematics which contained primarily antiquarian books including incunabula and 16th century editions. Various aspects of this valuabe book collection have been studied lately. Books from this dispersed collection have been revealed and examined de visu. Their cataloguing incudes the description of individual book copies in view of their provenance. The purpose of the article is to provide the information on a complex of owners’ recordings and dedicatory inscriptions as well as bookplates left on the books making an attempt to trace the fate of the copies incorporated in the library of the Odessa mathematician. The information collected is considered in the context of the history of Mathematics. Many may characterise both direct and indirect expressions of the readers’ interests in books and reading. The study of provenance records demonstrate that the copies acquired by professor Timchenko used to be in the libraries of a number of men of science – mathematicians, physicists, philologists, etc. The findings of this article enable to enlarge the database of provenance making the practical value and results of the research.

  6. Book review of “Imaging in Cellular and Tissue Engineering” edited by Y Hanry Yu and Nur Aida Abdul Rahim

    OpenAIRE

    Brey, Eric Michael

    2014-01-01

    This article is a review of the book “Imaging in Cellular and Tissue Engineering” (ISBN-13: 978-1439848036, $149.95, 298 Pages, 114 Illustrations) edited by Y Hanry Yu and Nur Aida Abdul Rahim published by the CRC Press (Taylor&Francis) in 2013. The contents of the book and its relevance to tissue engineering and regenerative medicine are discussed in this invited review.

  7. Acknowledgements [3. international conference on small angle neutron scattering dedicated to the 80 anniversary of Yu.M. Ostanevich, Dubna (Russian Federation), 6-9 June 2016

    International Nuclear Information System (INIS)

    2017-01-01

    The Organizers of the III International Conference on Small Angle Neutron Scattering dedicated to the 80-th anniversary of Yu. M. Ostanevich, acknowledge the financial support from the Grants of the Governmental Plenipotentiary Representatives of Romania, Slovakia, Czech Republic, scientific projects of the Cooperation Programmes JINR-Romania. Special gratitude to the JINR and FLNP administration and staff is expressed. The conference is also dedicated to the 60th Anniversary of the Joint Institute for Nuclear Research, Dubna. (paper)

  8. Identifying the candidate genes involved in the calyx abscission process of 'Kuerlexiangli' (Pyrus sinkiangensis Yu) by digital transcript abundance measurements.

    Science.gov (United States)

    Qi, Xiaoxiao; Wu, Jun; Wang, Lifen; Li, Leiting; Cao, Yufen; Tian, Luming; Dong, Xingguang; Zhang, Shaoling

    2013-10-23

    'Kuerlexiangli' (Pyrus sinkiangensis Yu), a native pear of Xinjiang, China, is an important agricultural fruit and primary export to the international market. However, fruit with persistent calyxes affect fruit shape and quality. Although several studies have looked into the physiological aspects of the calyx abscission process, the underlying molecular mechanisms remain unknown. In order to better understand the molecular basis of the process of calyx abscission, materials at three critical stages of regulation, with 6000 × Flusilazole plus 300 × PBO treatment (calyx abscising treatment) and 50 mg.L-1GA3 treatment (calyx persisting treatment), were collected and cDNA fragments were sequenced using digital transcript abundance measurements to identify candidate genes. Digital transcript abundance measurements was performed using high-throughput Illumina GAII sequencing on seven samples that were collected at three important stages of the calyx abscission process with chemical agent treatments promoting calyx abscission and persistence. Altogether more than 251,123,845 high quality reads were obtained with approximately 8.0 M raw data for each library. The values of 69.85%-71.90% of clean data in the digital transcript abundance measurements could be mapped to the pear genome database. There were 12,054 differentially expressed genes having Gene Ontology (GO) terms and associating with 251 Kyoto Encyclopedia of Genes and Genomes (KEGG) defined pathways. The differentially expressed genes correlated with calyx abscission were mainly involved in photosynthesis, plant hormone signal transduction, cell wall modification, transcriptional regulation, and carbohydrate metabolism. Furthermore, candidate calyx abscission-specific genes, e.g. Inflorescence deficient in abscission gene, were identified. Quantitative real-time PCR was used to confirm the digital transcript abundance measurements results. We identified candidate genes that showed highly dynamic changes in

  9. Towards the identification of alkaline phosphatase binding ligands in Li-Dan-Hua-Shi pills: A Box-Behnken design optimized affinity selection approach tandem with UHPLC-Q-TOF/MS analysis.

    Science.gov (United States)

    Tao, Yi; Huang, Surun; Gu, Xianghui; Li, Weidong; Cai, Baochang

    2018-05-30

    Alkaline phosphatase conjugated magnetic microspheres were synthesized via amide reaction, and employed as an effective adsorbent in affinity selection of binding ligands followed by UHPLC-Q-TOF/MS analysis. The analytical validity of the developed approach was evaluated under optimized conditions and the following figures of merit were obtained: linearity, 0.01-0.5 g L -1 with good determination coefficients (R 2  = 0.9992); limits of detection (LODs), 0.003 g L -1 ; and limits of quantitation (LOQ), 0.01 g L -1 . The precision (RSD%) of the proposed affinity selection approach was studied based on intra-day (0.8%) and inter-day (1.3%) precisions. Finally, the adsorbent was successfully applied to identification of binding ligands in Li-Dan-Hua-Shi pills and good recoveries were obtained in the range from 96.9 to 99.4% (RSDs 1.6-3.0%). Copyright © 2018 Elsevier B.V. All rights reserved.

  10. Tropical Journal of Pharmaceutical Research - Vol 15, No 3 (2016)

    African Journals Online (AJOL)

    Wan Wu, Wei Chen, Qiong Jin, 447-451 ... Chung-Shih Chen, Mei-Lin Wang, Rosa Huang Liu, Shih-Pin Chen, Tsong-Ming Lu, Wei-Yu Tsai, Chien-Fu Huang, ... Yan-Qiong Li, Rui Hu, Li-Hui Zhong, Qian Sun, You-Ping Yan, 527-533.

  11. Influence of Magnetic Ordering between Cr Adatoms on the Yu-Shiba-Rusinov States of the β -Bi2Pd Superconductor

    Science.gov (United States)

    Choi, Deung-Jang; Fernández, Carlos García; Herrera, Edwin; Rubio-Verdú, Carmen; Ugeda, Miguel M.; Guillamón, Isabel; Suderow, Hermann; Pascual, José Ignacio; Lorente, Nicolás

    2018-04-01

    We show that the magnetic ordering of coupled atomic dimers on a superconductor is revealed by their intragap spectral features. Chromium atoms on the superconductor β -Bi2Pd surface display Yu-Shiba-Rusinov bound states, detected as pairs of intragap excitations in tunneling spectra. By means of atomic manipulation with a scanning tunneling microscope's tip, we form Cr dimers with different arrangements and find that their intragap features appear either shifted or split with respect to single atoms. These spectral variations are associated with the magnetic coupling, ferromagnetic or antiferromagnetic, of the dimer, as confirmed by density functional theory simulations. The striking qualitative differences between the observed tunneling spectra prove that intragap Shiba states are extremely sensitive to the magnetic ordering on the atomic scale.

  12. Influence of Partial Dam Removal on Change of Channel Morphology and Physical Habitats: A Case Study of Yu-Sheng River

    Science.gov (United States)

    Hao Weng, Chung; Yeh, Chao Hsien

    2017-04-01

    The rivers in Taiwan have the characteristic of large slope gradient and fast flow velocity caused by rugged terrain. And Taiwan often aces many typhoons which will bring large rainfall in the summer. In early Taiwan, river management was more focus on flood control, flood protection and disaster reduction. In recent years, the rise of ecological conservation awareness for the precious fish species brings spotlight on the Taiwan salmon (Oncorhynchus masou formosanus) which lives in the river section of this study. In order to make sure ecological corridor continuing, dam removal is the frequently discussed measure in recent years and its impact on environmental is also highly concerned. Since the dam removal may causes severe changes to the river channel, the action of dam removal needs careful evaluation. As one of the endangered species, Taiwan salmon is considered a national treasure of Taiwan and it was originally an offshore migration of the Pacific salmon. After the ice age and geographical isolation, it becomes as an unique subspecies of Taiwan and evolved into landlocked salmon. Now the Taiwan salmon habitats only exists in few upstream creeks and the total number of wild Taiwan salmon in 2015 was about 4,300. In order to expand the connectivity of the fish habitats in Chi-Jia-Wan creek basin, several dam removal projects had completed with good results. Therefore, this paper focuses on the dam removal of Yu-Sheng creek dam. In this paper, a digital elevation model (DEM) of about 1 kilometer channel of the Yu-Sheng creek dam is obtained by unmanned aerial vehicle (UAV). Using CCHE2D model, the simulation of dam removal will reveal the impact on channel morphology. After model parameter identification and verification, this study simulated the scenarios of three historical typhoon events with recurrence interval of two years, fifteen years, and three decades under four different patterns of dam removal to identify the the head erosion, flow pattern, and

  13. Identification and Functional Analysis of microRNAs Involved in the Anther Development in Cotton Genic Male Sterile Line Yu98-8A

    Directory of Open Access Journals (Sweden)

    Xiaojie Yang

    2016-10-01

    Full Text Available Hybrid vigor contributes in a large way to the yield and quality of cotton (Gossypium hirsutum fiber. Although microRNAs play essential regulatory roles in flower induction and development, it is still unclear if microRNAs are involved in male sterility, as the regulatory molecular mechanisms of male sterility in cotton need to be better defined. In this study, two independent small RNA libraries were constructed and sequenced from the young buds collected from the sporogenous cell formation to the meiosis stage of the male sterile line Yu98-8A and the near-isogenic line. Sequencing revealed 1588 and 1536 known microRNAs and 347 and 351 novel miRNAs from male sterile and male fertile libraries, respectively. MicroRNA expression profiles revealed that 49 conserved and 51 novel miRNAs were differentially expressed. Bioinformatic and degradome analysis indicated the regulatory complexity of microRNAs during flower induction and development. Further RT-qPCR and physiological analysis indicated that, among the different Kyoto Encyclopedia Gene and Genomes pathways, indole-3-acetic acid and gibberellic acid signaling transduction pathways may play pivotal regulatory functions in male sterility.

  14. Surface-enhanced Raman scattering study of the healing of radial fractures treated with or without Huo–Xue–Hua–Yu decoction therapy

    International Nuclear Information System (INIS)

    Chen, Weiwei; Huang, Hao; Yu, Yun; Lin, Duo; Chen, Rong; Feng, Shangyuan; Lin, Jia

    2014-01-01

    This study aimed to assess, through surface-enhanced Raman scattering (SERS) spectroscopy, the incorporation of calcium hydroxyapatite (CHA ∼960 cm −1 ) and other biochemical substances in the repair of complete radial fractures in rabbits treated with or without Huo–Xue–Hua–Yu decoction (HXHYD) therapy. A total of 18 rabbits with complete radial fractures were randomly divided into two groups; one group was treated with HXHYD therapy and the other without therapy acted as a control. The animals were sacrificed at 15, 30 and 45 d after surgery. Specimens were routinely prepared for SERS measurement and high quality SERS spectra from a mixture of bone tissues and silver nanoparticles were obtained. The mineral-to-matrix ratios from the control and treated groups were calculated. Results showed that both deposition content of CHA measured by SERS spectroscopy and the mineral-to-matrix ratio in the treated group were always greater than those of the control group during the experiment, demonstrating that HXHYD therapy is effective in improving fracture healing and that SERS spectroscopy might be a novel tool to assess fracture healing. (letter)

  15. A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array", BMC Bioinformatics 2007, 8: 145.

    Science.gov (United States)

    Rueda, Oscar M; Diaz-Uriarte, Ramon

    2007-10-16

    Yu et al. (BMC Bioinformatics 2007,8: 145+) have recently compared the performance of several methods for the detection of genomic amplification and deletion breakpoints using data from high-density single nucleotide polymorphism arrays. One of the methods compared is our non-homogenous Hidden Markov Model approach. Our approach uses Markov Chain Monte Carlo for inference, but Yu et al. ran the sampler for a severely insufficient number of iterations for a Markov Chain Monte Carlo-based method. Moreover, they did not use the appropriate reference level for the non-altered state. We rerun the analysis in Yu et al. using appropriate settings for both the Markov Chain Monte Carlo iterations and the reference level. Additionally, to show how easy it is to obtain answers to additional specific questions, we have added a new analysis targeted specifically to the detection of breakpoints. The reanalysis shows that the performance of our method is comparable to that of the other methods analyzed. In addition, we can provide probabilities of a given spot being a breakpoint, something unique among the methods examined. Markov Chain Monte Carlo methods require using a sufficient number of iterations before they can be assumed to yield samples from the distribution of interest. Running our method with too small a number of iterations cannot be representative of its performance. Moreover, our analysis shows how our original approach can be easily adapted to answer specific additional questions (e.g., identify edges).

  16. Qing-Xin-Jie-Yu Granules in addition to conventional treatment for patients with stable coronary artery disease (QUEST Trial): study protocol for a randomized controlled trial.

    Science.gov (United States)

    Li, Shengyao; Guo, Ming; Mao, Huimin; Gao, Zhuye; Xu, Hao; Shi, Dazhuo

    2016-09-15

    Recurrent cardiovascular event remains high in stable coronary artery disease (SCAD), especially in patients with multiple risk factors, despite a high rate of use conventional treatment. Traditional Chinese Medicine (TCM) is a promising complementary and alternative medicine for treating SCAD, while evidence for its effect on long-term survival is limited. This study was designed to test if Chinese herbal medicine in addition to conventional treatment is more effective than conventional treatment alone in reducing major adverse cardiac event (MACE) for SCAD patients with multiple risk factors during a 1-year follow-up. This is a multicenter, placebo-controlled, double-blinded, randomized controlled clinical trial. A total of 1500 patients are randomized in a 1:1 ratio to receive the Qing-Xin-Jie-Yu Granules (QXJYG) or the placebo granules, twice daily for 6 months. The primary outcome is the combined outcomes including cardiac death, nonfatal myocardial infarction and revascularization. The secondary outcome is the combined outcomes including all-cause mortality, re-admission for acute coronary syndrome (ACS), heart failure, malignant supraventricular and ventricular arrhythmia influencing hemodynamics, ischemic stroke, and other thromboembolic events during 1-year follow-up. The assessment is performed at baseline (before randomization), 1, 3, 6, 9, and 12 months after randomization. This is the first multicenter trial sponsored by the national funding of China to evaluate TCM in combination with conventional treatment on 1-year survival in high-risk SCAD patients. If successful, it will provide an evidence-based complementary therapeutic approach for reducing MACE from SCAD. The trial was registered in the Chinese Clinical Trial Registry on December 28, 2013. The registration number is ChiCTR-TRC-13004370 .

  17. Xue-fu-Zhu-Yu decoction protects rats against retinal ischemia by downregulation of HIF-1α and VEGF via inhibition of RBP2 and PKM2.

    Science.gov (United States)

    Tan, Shu-Qiu; Geng, Xue; Liu, Jorn-Hon; Pan, Wynn Hwai-Tzong; Wang, Li-Xiang; Liu, Hui-Kang; Hu, Lei; Chao, Hsiao-Ming

    2017-07-14

    Retinal ischemia-related eye diseases result in visual dysfunction. This study investigates the protective effects and mechanisms of Xue-Fu-Zhu-Yu decoction (XFZYD) with respect to retinal ischemia. Retinal ischemia (I) was induced in Wistar rats by a high intraocular pressure (HIOP) of 120 mmHg for 1 h, which was followed by reperfusion of the ischemic eye; the fellow untreated eye acted as a control. Electroretinogram (ERG), biochemistry and histopathology investigations were performed. Significant ischemic changes occurred after ischemia including decreased ERG b-wave ratios, less numerous retinal ganglion cells (RGCs), reduced inner retinal thickness, fewer choline acetyltransferase (ChAT) labeled amacrine cell bodies, increased glial fibrillary acidic protein (GFAP) immunoreactivity and increased vimentin Müller immunolabeling. These were accompanied by significant increases in the mRNA/protein concentrations of vascular endothelium growth factor, hypoxia-inducible factor-1α, pyruvate kinase M2 and retinoblastoma-binding protein 2. The ischemic changes were concentration-dependently and significantly altered when XFZYD was given for seven consecutive days before or after retina ischemia, compared to vehicle. These alterations included enhanced ERG b-wave amplitudes, more numerous RGCs, enhanced inner retinal thickness, a greater number of ChAT immunolabeled amacrine cell bodies and decreased GFAP/vimentin immunoreactivity. Furthermore, decreased mRNA levels of VEGF, HIF-1α, PKM2, and RBP2 were also found. Reduced protein concentrations of VEGF, HIF-1α, PKM2, and RBP2 were also demonstrated. Furthermore, there was an inhibition of the ischemia-associated increased ratios (target protein/β-actin) in the protein levels of VEGF, HIF-1α, PKM2, and RBP2, which were induced by Shikonin, JIB-04 or Avastin. XFZYD would seem to protect against well-known retinal ischemic changes via a synergistic inhibition of RBP2 and PKM2, as well as down-regulation of HIF-1

  18. Review of the Monograph: Seleznev Yu.V. Russkie knyaz’ya pri dvore khanov Zolotoy Ordy (Russian Princes at the Court of the Golden Horde Khans

    Directory of Open Access Journals (Sweden)

    Nesin M.A.

    2017-12-01

    Full Text Available This article contains a review of the monograph by Yu.V. Seleznev published in early 2017 and dedicated to the relations of Russian princes with the Golden Horde’s khans and their status among the Golden Horde’s nobility. This work is the first comprehensive study in the historiography of this issue for all two and a half centuries of the Tartar domination. The monograph was published for the first time in 2013 and served as the basis for a doctoral dissertation, which Seleznev defended in 2015. The book was reprinted with certain changes in 2017. The book commendably contains an abundance of factual material through the use of diverse sources and strands of historiography. Seleznev examines the social terminology of Golden Horde-Russian relations, the structure of the Golden Horde’s nobility and the trips of princes to the Horde, drawing attention not only to the status of the great Vladimir and Moscow princes, but also that of other great and appanage princes. He makes a significant contribution to the resolving the debate regarding the nature of the Golden Horde’s domination in Rus’ by examining in detail the relationship of the Russian princes with the Golden Horde’s authorities in different years. The book’s author proposed to divide the Golden Horde’s “yoke” into seven periods characterized by “changes in the degree of sovereignty and jurisdiction of the khan in relation to Russian principalities”. The author of this review agrees with the main conclusions of the book under review, but at the same time he notes some reservations and criticisms, which do not, however, reduce the academic caliber of the monograph.

  19. Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4+CD25+ regulatory T cells

    Directory of Open Access Journals (Sweden)

    Li JY

    2016-04-01

    Full Text Available Jingya Li,1,* Ruizhen Zhao,1,* Xiaoli Li,1 Wenjun Sun,1 Miao Qu,1 Qisheng Tang,1 Xinke Yang,1 Shujing Zhang2 1Third Affiliated Hospital, 2School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing, People’s Republic of China *These authors contributed equally to this work Background: Shen-Qi-Jie-Yu-Fang (SJF is composed of eight Chinese medicinal herbs. It is widely used in traditional Chinese medicine for treating postpartum depression (PPD. Previous studies have shown that SJF treats PPD through the neuroendocrine mechanism. Aim: To further investigate the effect of SJF on the immune system, including the inflammatory response system and CD4+CD25+ regulatory T (Treg cells. Materials and methods: Sprague Dawley rats were used to create an animal model of PPD by inducing hormone-simulated pregnancy followed by hormone withdrawal. After hormone withdrawal, the PPD rats were treated with SJF or fluoxetine for 1, 2, and 4 weeks. Levels of Treg cells in peripheral blood were measured by flow cytometry analysis. Serum interleukin (IL-1β and IL-6 were evaluated by enzyme-linked immunosorbent assay, and gene and protein expressions of IL-1RI, IL-6Rα, and gp130 in the hippocampus were observed by reverse-transcription polymerase chain reaction and Western blot. Results: Serum IL-1β in PPD rats increased at 2 weeks and declined from then on, while serum IL-6 increased at 1, 2, and 4 weeks. Both IL-1β and IL-6 were downregulated by SJF and fluoxetine. Changes in gene and protein expressions of IL-1RI and gp130 in PPD rats were consistent with changes in serum IL-1β, and were able to be regulated by SJF and fluoxetine. The levels of Treg cells were negatively correlated with serum IL-1β and IL-6, and were decreased in PPD rats. The levels of Treg cells were increased by SJF and fluoxetine. Conclusion: Dysfunction of proinflammatory cytokines and Tregs in different stages of PPD was attenuated by SJF and fluoxetine through

  20. Therapeutic effects of Qian-Yu decoction and its three extracts on carrageenan-induced chronic prostatitis/chronic pelvic pain syndrome in rats.

    Science.gov (United States)

    Zhang, Keda; Zeng, Xiaobin; Chen, Yonggang; Zhao, Rong; Wang, Hui; Wu, Jinhu

    2017-01-25

    Qian-Yu decoction (QYD) is a traditional Chinese medicinal recipe composed of Radix astragali (Astragalus membranaceus (Fisch.) Bunge var. mongholicus (Bunge) P.K. Hsiao, Fabaceae ), Herba epimedii (Epimedium brevicornum Maxim., Berberidaceae), Herba leonuri (Leonurus japonicus Houtt., Lamiaceae), Cortex phellodendri (Phellodendron chinense Schneid., Rutaceae) and Radix achyranthis bidentatae (Achyranthes bidentata Bl., Amaranthaceae). This study aimed to evaluate the therapeutic activity of QYD against carrageenan-induced chronic prostatic/chronic pelvic pain syndrome (CP/CPPS) in rats and further elucidate its effective components. Three types of components, total polysaccharides, total flavonoids and total saponins were separately extracted from QYD. Carrageenan-induced CP/CPPS rats were intragastrically administered with lyophilized product of QYD, individual extracts and all the combined forms of extracts for three weeks. Prostatic index (PI) was determined and histopathological analysis was performed. The levels of tumor necrosis factor alpha (TNF-α), interleukin-1 beta (IL-1β), cyclooxygenase-2 (COX-2) and prostaglandin E2 (PEG2) in rat prostate tissues were measured using ELISA. The production of inducible nitric oxide synthase (iNOS) was evaluated by an enzymatic activity assay, and the release of nitric oxide (NO) was determined by a nitrate/nitrite assay. Treatment with QYD significantly ameliorated the histological changes of CP/CPPS rats and reduced the PI by 44.3%, with a marked downregulation of TNF-α (42.8% reduction), IL-1β (45.3%), COX-2 (36.6%), PGE2 (44.2%), iNOS (54.1%) and NO (46.0%). Each of three extracts attenuated the symptom of CP/CPPS, but much more weakly than QYD. The combined administration of three extracts showed efficacy comparable to that of QYD while better than that of any combination of two extracts. A principal component analysis of the six inflammatory mediators as variables indicated that the effects of TS on CP

  1. Potential effectiveness of Chinese herbal medicine Yu ping feng san for adult allergic rhinitis: a systematic review and meta-analysis of randomized controlled trials.

    Science.gov (United States)

    Luo, Qiulan; Zhang, Claire Shuiqing; Yang, Lihong; Zhang, Anthony Lin; Guo, Xinfeng; Xue, Charlie Changli; Lu, Chuanjian

    2017-11-06

    Chinese herbal medicine formula Yu ping feng san (YPFS) is commonly used for allergic rhinitis (AR). Previous review had summarized the effectiveness and safety of YPFS, however without any subgroup analysis performed to provide detailed evidence for guiding clinical practice. YPFS was recommended for the management of AR by Chinese medicine clinical practice guideline, but the treatment duration of YPFS was also not specified. The aim of this study is to evaluate the effectiveness and safety of YPFS in treating adult AR with the most recent evidence, and attempt to specify the duration of utilisation through subgroup meta-analyses. Seven databases were searched from their inceptions to September 2017. Randomized controlled trials (RCTs) evaluating YPFS for adult AR were included. Methodological quality of studies was assessed using the Cochrane risk of bias tool. Meta-analysis and subgroup meta-analyses were conducted for evaluating the effectiveness of YPFS. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used for rating the quality of evidence. Twenty-two RCTs involving 23 comparisons were included in this review. YPFS was compared to placebo, pharmacotherapy, and used as an add-on treatment compared to pharmacotherapy. Meta-analyses were feasible for the outcomes of four individual nasal symptom scores and "effective rate". Four individual nasal symptom scores decreased after YPFS' combination treatment: itchy nose (MD-0.46, 95% CI[-0.50, -0.42]), sneezing (MD-0.41, 95% CI[-0.47, -0.35]), blocked nose (MD-0.46, 95% CI[-0.54, -0.39]) and runny nose (MD-0.42, 95% CI[-0.58, -0.26]). Based on "effective rate", meta-analysis showed that YPFS did not achieve better effect than pharmacotherapy (RR1.07, 95%CI [0.94, 1.22), but its combination with pharmacotherapy seemed more effective than pharmacotherapy alone (RR1.27, 95%CI [1.19, 1.34]) (low quality). Subgroup analysis suggested that YPFS was not superior to the second

  2. Validation of the YuWell YE690A upper-arm blood pressure monitor, for clinic use and self-measurement, according to the European Society of Hypertension International Protocol revision 2010.

    Science.gov (United States)

    Chen, Qi; Lei, Lei; Li, Yan; Wang, Ji-Guang

    2017-10-01

    The present study aimed to evaluate the accuracy of the automated oscillometric upper-arm blood pressure monitor YuWell YE690A for blood pressure measurement according to the International Protocol of the European Society of Hypertension revision 2010. Systolic and diastolic blood pressures were measured sequentially in 33 adult Chinese (12 women, 44.2 years of mean age) using a mercury sphygmomanometer (two observers) and the YE690A device (one supervisor). A total of 99 pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. All the blood pressure requirements were fulfilled. The YuWell YE690A device achieved the targets in part 1 of the validation study. The number of absolute differences between device and observers within 5, 10, and 15 mmHg was 79/99, 96/99, and 97/99, respectively, for systolic blood pressure and 72/99, 95/99, and 98/99, respectively, for diastolic blood pressure. The device also fulfilled the criteria in part 2 of the validation study. Thirty-one and 25 participants for systolic and diastolic blood pressure, respectively, had at least two of the three device-observer differences within 5 mmHg (required ≥24). No participant for systolic and two participants for diastolic blood pressure had all the three device-observer comparisons greater than 5 mmHg. The YuWell blood pressure monitor YE690A has passed the requirements of the International Protocol revision 2010 and hence can be recommended for blood pressure measurement in adults.

  3. 文化漫游与精神家园——当代中国文化散文的公共语境 (Cultural Tours and the Spiritual Home: On Yu Qiuyu and Contemporary Chinese Cultural Essays

    Directory of Open Access Journals (Sweden)

    Yi Zheng

    2007-01-01

    Full Text Available The essay explores the public social dimension of the “great cultural essays” as a popular post-socialist genre. It looks into the genre’s emergence and popularity as part of the making of a middleclass taste in contemporary China and its claim to a re-imagined cultural national inheritance. In particular, the discussion focuses on the example of essayist Yu Qiuyu and examines the implications of his successful transformation of an obsolete historical “Culture” into a desirable commodity that offers spiritual home to the aspiring and successful of a “Greater China”.

  4. A New Book on the Law System of the Golden Horde: Pochekaev R.Yu. Legal Culture of the Golden Horde (Historical and Legal Essays) (Moscow: Yurlitinform, 2015. 312 p.)

    OpenAIRE

    D.V. Nefedov

    2016-01-01

    This book is a study at the intersection of such academic disciplines as general history, history of state and law and source study. The subcect of R.Yu. Pochevalev’s book appears very relevant since the interest of the scientific community and readership toward the Golden Horde and its role in the history of the Russian state remains traditionally high for several centuries. However, the author is trying to take a fresh look at this state and refute the stereotype of the Golden Horde as a...

  5. Exotic aspects of black holes: an astronaut near the horizon (on the methodological note by A A Grib and Yu V Pavlov 'Is it possible to see the infinite future of the Universe when falling into a black hole?')

    International Nuclear Information System (INIS)

    Cherepashchuk, Anatolii M

    2009-01-01

    We comment on the methodological note by A A Grib and Yu V Pavlov [Phys. Usp. 52 257 (2009)] to show that its authors are incorrect in understanding a passage that they quote from A M Cherepashchuk's book Black Holes in the Universe (Fryazino: Vek-2, 2005, p.7) and which supposes an astronaut to be at rest in the vicinity of the horizon (not to fall freely into a black hole!). With this error corrected, Grib and Pavlov's note is quite useful methodologically. (letters to the editors)

  6. Analysis of neutron spectra and fluxes obtained with cold and thermal moderators at IBR-2 reactor: experimental and computer modeling studies at small-angle scattering YuMO setup

    International Nuclear Information System (INIS)

    Kuklin, A.I.; Rogov, A.D.; Gorshkova, Yu.E.; Kovalev, Yu.S.; Kutuzov, S.A.; Utrobin, P.K.; Rogachev, A.V.; Ivan'kov, O.I.; Solov'ev, D.V.; Gordelij, V.I.

    2011-01-01

    Results of experimental and computer modeling investigations of neutron spectra and fluxes obtained with cold and thermal moderators at the IBR-2 reactor (JINR, Dubna) are presented. The studies are done for small-angle neutron scattering (SANS) spectrometer YuMO (beamline number 4 of the IBR-2). The measurements of neutron spectra for two methane cold moderators are done for the standard configuration of the SANS instrument. The data from both moderators under different conditions of their operation are compared. The ratio of experimentally determined neutron fluxes of cold and thermal moderators at different wavelength is shown. Monte Carlo simulations are done to determine spectra for cold methane and thermal moderators. The results of the calculations of the ratio of neutron fluxes of cold and thermal moderators at different wavelength are demonstrated. In addition, the absorption of neutrons in the air gaps on the way from the moderator to the investigated sample is presented. SANS with the protein apoferritin was done in the case of cold methane as well as a thermal moderator and the data were compared. The perspectives for the use of the cold moderator for a SANS spectrometer at the IBR-2 are discussed. The advantages of the YuMO spectrometer with the thermal moderator with respect to the tested cold moderator are shown

  7. Molecular diversity analysis of Tetradium ruticarpum (WuZhuYu) in China based on inter-primer binding site (iPBS) markers and inter-simple sequence repeat (ISSR) markers.

    Science.gov (United States)

    Xu, Jing-Yuan; Zhu, Yan; Yi, Ze; Wu, Gang; Xie, Guo-Yong; Qin, Min-Jian

    2018-01-01

    "Wu zhu yu", which is obtained from the dried unripe fruits of Tetradium ruticarpum (A. Jussieu) T. G. Hartley, has been used as a traditional Chinese medicine for treatment of headaches, abdominal colic, and hypertension for thousands of years. The present study was designed to assess the molecular genetic diversity among 25 collected accessions of T. ruticarpum (Wu zhu yu in Chinese) from different areas of China, based on inter-primer binding site (iPBS) markers and inter-simple sequence repeat (ISSR) markers. Thirteen ISSR primers generated 151 amplification bands, of which 130 were polymorphic. Out of 165 bands that were amplified using 10 iPBS primers, 152 were polymorphic. The iPBS markers displayed a higher proportion of polymorphic loci (PPL = 92.5%) than the ISSR markers (PPL = 84.9%). The results showed that T. ruticarpum possessed high loci polymorphism and genetic differentiation occurred in this plant. The combined data of iPBS and ISSR markers scored on 25 accessions produced five clusters that approximately matched the geographic distribution of the species. The results indicated that both iPBS and ISSR markers were reliable and effective tools for analyzing the genetic diversity in T. ruticarpum. Copyright © 2018 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

  8. A New Book on the Law System of the Golden Horde: Pochekaev R.Yu. Legal Culture of the Golden Horde (Historical and Legal Essays (Moscow: Yurlitinform, 2015. 312 p.

    Directory of Open Access Journals (Sweden)

    D.V. Nefedov

    2016-12-01

    Full Text Available This book is a study at the intersection of such academic disciplines as general history, history of state and law and source study. The subcect of R.Yu. Pochevalev’s book appears very relevant since the interest of the scientific community and readership toward the Golden Horde and its role in the history of the Russian state remains traditionally high for several centuries. However, the author is trying to take a fresh look at this state and refute the stereotype of the Golden Horde as a some kind of bunch of nomads who lived only by plundering neighboring sedentary peoples. He succeeds in this by studying such an important part of the Golden Horde history as its law and legal culture. The book examines a number of questions on the history of state and law of the Golden Horde, which have not previously been the subject of a special study (for example, possessions of the Golden Horde in other uluses, dualism of power in different states, relations between authorities and traders, etc.. On some other issues that have already been studied by experts, he proposes new interpretations in the framework of historical and legal approach (for example, the causes of intestine strife in the Golden Horde in the mid-14th century, yarliks of the Golden Horde khans granted to the Russian Chruch, relations of the Golden Horde rulers and Italian colonies in the Northern Black Sea region. The author examines to a great extent the themes of state and legal regulation of economic relations: status of merchants in the Golden Horde and post-Golden Horde states, role of economic sanctions in the resolution of political conflicts. In other essays contained in the book, the author also emphasizes the role of the economic component of the political and legal relations. For example, R.Yu. Pochekaev convincingly shows that relations of the Golden Horde with other states of the Mongol Empire was based on the principle of mutual provision of possessions to the rulers of

  9. Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway.

    Science.gov (United States)

    Ding, Kang; Wang, Yan; Jiang, Weimin; Zhang, Yu; Yin, Hongping; Fang, Zhuyuan

    2015-03-25

    Qian Yang Yu Yin Granule (QYYYG), a traditional Chinese herbal medicine, has been indicated for renal damage in hypertension for decades in China, but little remains known regarding its underlying molecular mechanism. Therefore, we performed the current study in order to investigate the underlying molecular mechanism of QYYYG in the treatment of hypertensive renal damage. We hypothesize that QYYYG relieves hypertensive renal injury through an angiotensin II (Ang II)-nicotinamide adenine dinucleotide phosphate (NAPDH)-oxidase (NOX)-reactive oxygen species (ROS) pathway. In this study, we investigated the effects of QYYYG-containing serum (QYGS) in human mesangial cells (HMCs) against Ang II-induced cell proliferation, ROS production, and inflammation through the seropharmacological method. We found that QYGS could inhibit cell proliferation in Ang II-treated HMCs. In addition, QYGS considerably suppressed production of ROS, decreased mRNA and protein expression of NAPDH-oxidase 4 (NOX4), p22 (phox) , and activated Ras-related C3 botulinum toxin substrate 1 (GTP-Rac1); as well as counteracted the up-regulation of inflammatory markers including tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB) p65, and interleukin 6 (IL-6). These effects were further confirmed in HMCs transfected with specific small interfering RNA (siRNA) targeting NOX4. Taken together, these results suggest that a NOX4-dependent pathway plays an important role in regulating the inhibitory effect of QYGS. Our findings provide new insights into the molecular mechanisms of QYYYG and their role in the treatment of hypertensive nephropathy.

  10. Magnetic Field Strength Evaluation Yu. S. Yefimov

    Indian Academy of Sciences (India)

    physical task is to evaluate the strength and topology of magnetic field in blazars and related ... polarization, spectral index of radiation, ratio of apparent velocity of the motion of matter along .... A detailed analysis of the evaluation of physical.

  11. Laule : [luuletused] / Li Yu ; tlk. Jaan Kaplinski

    Index Scriptorium Estoniae

    Yu, Li

    2002-01-01

    Sisu : "Vahused lained kui kuhjaksid kokku lund..."; "Õhtuks mingitud näo ja ihu valendus..."; "Kirkad lilled, hämus kuu, udu hõljuv loor..."; "Pool kevadet lahkumisest..."; "Sõnatult astun läänekambrisse..."; "metsapuilt on pudenenud kevadevärvid..."; "Vihmasabin kardina taga..."; "Möödunut võib ainult leinata..."; "Öö oli rajune-vihmane...";"Kevadlilled, sügisekuu - kaua veel..."

  12. Chuangzaoli xinlixue yu jiechu rencai peiyang

    DEFF Research Database (Denmark)

    Shi, Jiannong; Chen, N.; Du, Xiangyun

    2012-01-01

    as individual’s personal characteristics rather as the results of active interaction of creative individual and the environment. Creativity is a process of accumulation from quantitative changes to qualitative changes during a period of time. Meanwhile the authors discuss issues about individual’s creativity......The authors emphasize the importance of systemic perspectives for understanding human creativity after briefly introducing and commenting different theories or perspectives on creativity. It is emphasized that the manifestation of creativity or excellent achievement should not be treated...

  13. Selected papers of Yu. I. Manin

    CERN Document Server

    Manin, Yu I

    1996-01-01

    The book is a collection of research and review articles in several areas of modern mathematics and mathematical physics published in the span of three decades. The ICM Kyoto talk "Mathematics as Metaphor" summarises the author's view on mathematics as an outgrowth of natural language.

  14. Effect of Yi-nao-jie-yu decoction on γ-aminobutyric acid type A receptor in the hippocampus and serum inflammatory factors in a rat model of poststroke anxiety

    Directory of Open Access Journals (Sweden)

    Zhang W

    2016-11-01

    Full Text Available Wen Zhang,1 Ruizhen Zhao,1 Xiaoli Li,1 Xia Cui,1 Zijun Zhao,1 Yingqiu Mao,2 Fengzhi Wu,3 Qisheng Tang1 1Department of Encephalopathy, The Third Affiliated Hospital, 2Center of Scientific Research, 3Center of Journals, Beijing University of Chinese Medicine, Chaoyang District, Beijing, People’s Republic of China Background: The Yi-nao-jie-yu decoction (YNJYD is a herbal preparation widely used in the clinics of traditional Chinese medicine and has been recently used as an important new therapeutic agent in poststroke anxiety (PSA. The neuroendocrine–immune system plays an important role in PSA mechanisms, although the modulating effects of YNJYD remain unknown. This study investigated the potential effects of YNJYD on the neuroendocrine–immune system in a rat model of PSA.Materials and methods: The PSA model was induced by injecting collagenase (type VII into the right globus pallidus, accompanied by empty water bottle stimulation for 2 weeks. The sham group and the PSA model group were gavaged with saline, while the treatment groups received buspirone (BuSpar or YNJYD. Behavior was evaluated with the open field test and elevated plus maze once a week. Pathological changes were observed by hematoxylin and eosin staining. Serum levels of tumor necrosis factor, interleukin (IL-6, adrenocorticotropic hormone, thyroid stimulating hormone, free triiodothyronine, free thyroxine, IL-1α, and cortisol were detected by radioimmunoassay. Expression of the γ-aminobutyric acid type A receptor (GABAAR α2 subunit was examined by Western blot and real-time polymerase chain reaction.Results: YNJYD-treated rats exhibited significantly better recovery than BuSpar-treated rats at 21 days and 28 days in the open field test and elevated plus maze. Hematoxylin and eosin staining revealed neural repair in the hippocampus in the treatment groups. Serum levels of IL-1α in the YNJYD group were significantly less than those in the model group and the Bu

  15. Multichannel time-analyser with an electrostatic memory tube; Analyseur en temps a plusieurs canaux, avec memoire a potentioscopes; Mnogokanal'nye vremennye analizatory s pamyat'yu na potentsialoskopakh; Analizador multicanal de tiempo con tubo de memoria electrostatico

    Energy Technology Data Exchange (ETDEWEB)

    Ignat' ev, K G; Kirpichnikov, I V; Sukhoruchkin, S I

    1962-04-15

    forma de graficos y de datos numericos en fichas perforadas. (author) [Russian] V ITEHF AN SSSR byli so z d a ny dva mnogokanal'nykh vremennykh analizatora impul'sov s ''pamyat'yu'' na potentsialoskopakh JIH-4. V nastoyashchee vremya oni ISPOL'ZUYUTSYA V razlichnykh izmereniyakh i imeyut sleduyushchie kharakteristiki: chislo kanalov - 1024 i 2048; vremennaya shirina kanalov ot 0,2 mksek. i bol'she; emkost' kanalov - 4096 imp i 1024 imp; chastota zapuska analizatoroa do 1000 raz v sek; velichina zagruzki do 1000 imp/sek. Rezul'taty izmerenij vydayutsya analizatorami v vide grafikov i chislovykh dannykh na perfokartakh. (author)

  16. Effect of XingPiJieYu decoction on spatial learning and memory and cAMP-PKA-CREB-BDNF pathway in rat model of depression through chronic unpredictable stress.

    Science.gov (United States)

    Wang, Chunye; Guo, Jianyou; Guo, Rongjuan

    2017-01-24

    Depression is a mental disorder characterized by a pervasive low mood and loss of pleasure or interest in usual activities, and often results in cognitive dysfunction. The disturbance of cognitive processes associated with depression, especially the impairment of learning and memory, exacerbates illness and increases recurrence of depression. XingPiJieYu (XPJY) is one of the most widely clinical formulas of traditional Chinese medicine (TCM) and can improve the symptoms of depression, including learning and memory. However, its regulatory effects haven't been comprehensively studied so far. Recently, some animal tests have indicated that the cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA)-cAMP response element-binding protein (CREB)-brain derived neurotrophic factor (BDNF) signaling pathway in hippocampus is closely related to depression and the pathogenesis of cognitive function impairments. The present study was performed to investigate the effect and mechanism of XPJY on depression and learning and memory in animal model. The rat model of depression was established by chronic unpredictable stress (CUS) for 21 days. The rats were randomly divided into six groups: control group, CUS group, CUS + XPJY (1.4 g/kg, 0.7 g/kg and 0.35 g/kg) groups, and CUS + sertraline (10 mg/kg) group. The sucrose preference, open field exploration and Morris water maze (MWM) were tested. The expression of cAMP, CREB, PKA and BDNF protein in hippocampus was examined with Elisa and Western Blot. The mRNA level of CREB and BDNF in hippocampus was measured with PCR. The results demonstrated that rats subjected to CUS exhibited decreases in sucrose preference, total ambulation, percentage of central ambulation, rearing in the open field test and spatial performance in the MWM. CUS reduced the expression of cAMP, PKA, CREB and BDNF in hippocampus of model rats. These effects could be reversed by XPJY. The results indicated that XPJY can improve depression and

  17. LETTERS TO THE EDITORS: Exotic aspects of black holes: an astronaut near the horizon(on the methodological note by A A Grib and Yu V Pavlov "Is it possible to see the infinite future of the Universe when falling into a black hole?")

    Science.gov (United States)

    Cherepashchuk, Anatolii M.

    2009-08-01

    We comment on the methodological note by A A Grib and Yu V Pavlov [Phys. Usp. 52 257 (2009)] to show that its authors are incorrect in understanding a passage that they quote from A M Cherepashchuk's book Black Holes in the Universe (Fryazino: Vek-2, 2005, p.7) and which supposes an astronaut to be at rest in the vicinity of the horizon (not to fall freely into a black hole!). With this error corrected, Grib and Pavlov's note is quite useful methodologically.

  18. Zhu Qing Wang

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Zhu Qing Wang. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 543-548. Highly sensitive optical chemosensor for the detection of Cu using a rhodamine B spirolatam · Gen Hua Wu Dong Xiang Wang Da Yu Wu Yuan Gao Zhu Qing Wang.

  19. Photodetachment cross-section of in a three-dimensional cubical ...

    Indian Academy of Sciences (India)

    DE-HUA WANG

    2017-10-19

    Oct 19, 2017 ... DE-HUA WANG. ∗. , PANG-ZHI .... on the surfaces along x, y, z directions, respectively. Then the ..... [20] Y Han, L F Wang, S Y Ran and G C Yang, Physica B. 405, 3082 ... [36] D H Wang, Y J Yu and S L Lin, Chin. Opt. Lett.

  20. People’s Republic of China Scientific Abstracts, Number 185

    Science.gov (United States)

    1978-02-14

    CONTENTS PAGE HANG-K’UNG CHIH-SHIH [AERONAUTICAL KNOWLEDGE] No 10, October 1977 .... 1 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 3, September 1977 8...launch units; 3) Chairman Hua visiting an earthquake damaged region; 4) a group of female pilots of a minority race. 3012 CSO: 4009 ACTA BOTANICA ...CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICä] in Chinese Vol 19 No 3, Sep 77 pp 167-171 TEXT OF ENGLISH ABSTRACT: 1. The process of microsporogenesis

  1. The production of radioisotopes with a betatron using an internal bombarding technique; Production de radioisotopes par bombardement interne dans un betatron; Proizvodstvo radioizotopov s pomoshch'yu betatrona s ispol'zovaniem metoda vnutrennej bombardirovki; Obtencion de radioisotopos por bombardeo interno en el betatron

    Energy Technology Data Exchange (ETDEWEB)

    Morinaga, H [Department of Physics, Tohoku University, Sendai (Japan)

    1962-01-15

    pueden servir para la obtencion de isotopos. Con frecuencia es conveniente emplear isotopos de periodo corto debido a su rapida desintegracion, al hecho de que emitan radiaciones de alta energia y a la facilidad con que pueden obtenerse incluso sin necesidad de poseer conocimientos especiales. (author) [Russian] Razrabotan i uspeshno ispol'zuetsya novyj metod proizvodstva radioizotopov s vysokoj udel'noj aktivnost'yu s pomoshch'yu betatrona. Podvergaemye aktivatsii materialy pomeshchayutsya vnutr' vakuumnoj kamery betatrona v kontse slepogo tsilindra, ustanovlennogo izvne; takim obrazom, proby podvergayutsya bombardirovke pri odnoj atmosfere neposredstvenno za mishen'yu tormoznogo izlucheniya, gde intensivnost' radiatsii chrezvychajno vysoka. Aktivnost' pri nasyshchenii Cu{sup 62}, vyzvannaya v nebol'shoj chastitse medi, prevyshala 1 millikyuri, i poluchaemaya naivysshaya udel'naya aktivnost' priblizitel'no v 500 raz prevyshala aktivnost', vyzvannuyu v obychnom ustrojstve. Do sikh por ehtot metod vnutrennej misheni ispol'zuetsya tol'ko dlya rabot v oblasti yadernoj spektroskopii; bylo ustanovleno vosem' novykh vidov radioaktivnykh izotopov (Co{sup 63}, Ga{sup 75}, As{sup 81}, In{sup 121}, In{sup 123}, Tm{sup 173}, Tm{sup 175} i Ac{sup 231}). Gibkost' takogo metoda bombardirovki otkryvaet novye vozmozhnosti, t.k. meditsinskij, promyshlennyj, a takzhe issledovatel'skij betatrony mogut ispol'zovat'sya dlya proizvodstva izotopov. Korotkozhivushchie izotopy, kotorye chasto yavlyayutsya bolee udobnymi pri razlichnykh vidakh primeneniya vsledstvie ikh bystrogo raspada i obychno vysokoj ehnergii radiatsii, mogut byt' bystro polucheny bez kakogo-libo dopolnitel'nogo umeniya. (author)

  2. China Debates the Future Security Environment

    Science.gov (United States)

    2000-01-01

    Bike, Zhot~uo da qushi (China megatrends )( Belling: Hualing chubanshe, 1996). For warnings on the need to conceal increasing national power, see Ma...became Japan’s prime minister in 1957. Troop 731, which had engaged in biological warfare experiments, was exempted from trial. In March 1950, all...gongye chubanshe, 1998. Lu Hui. He hua sheng wuqi de h’shi yu weilai CFhe history and future of nuclear, chemical, and biological weapons). Beijing

  3. Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor

    OpenAIRE

    Wang,Guang-Yu; Li,Ling; Liu,Bo; Han,Xiao; Wang,Chunhua; Wang,Jiwen

    2018-01-01

    Guang-Yu Wang,1,* Ling Li,2,* Bo Liu,1 Xiao Han,1 Chun-Hua Wang,1 Ji-Wen Wang3 1Department of Neurosurgery, 2Department of Pediatrics, Qilu Children’s Hospital of Shandong University, Jinan, Shandong, 3Department of Neurology, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Pudong New District, Shanghai, People’s Republic of China *These authors contributed equally to this work Purpose: This study aimed to explore ...

  4. People’s Republic of China Scientific Abstracts No. 178

    Science.gov (United States)

    1977-10-27

    of hepatic colls were observed by eleotron microscopy after carbon tetrachloride intoxication in mice . The hepatic cellular injuries were protected...administration in [continuation of SHENG-WU HUA-HSUEH YU SHENG-WU WU-LI-HSUEH-PAO Vol 8, No A, Dec 76 pp 333-340] mice . It is transformed from lipid...preparations for monopolizing the technique by capi- talist and revisionist countries. In a socialist country, the author claims, the purpose of developing

  5. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 85-91 Research Article. Cloning and study of adult-tissue-specific expression of Sox9 in Cyprinus carpio · Du Qi-Yan Wang Feng-Yu Hua Hui-Ying Chang Zhong-Jie · More Details Abstract Fulltext PDF. The Sox9 gene is one of the important transcription factors in the development of many tissues and organs, particularly ...

  6. You Are Whom You Eat: Cannibalism in Contemporary Chinese Fiction and Film

    OpenAIRE

    Tsai, Yun-Chu

    2016-01-01

    My project, You Are Whom You Eat: Cannibalism in Contemporary Chinese Fiction and Film, studies cannibalism in the works of Yu Hua, Mo Yan, and Lillian Lee. In contrast to other scholars who have interpreted cannibalism in modern and contemporary Chinese literature as merely allegorical, I find that cannibalism is better understood as both allegorical and literal. The trope of cannibalism uncovers the potential incorporation of Chinese gourmandism (Chinese culture of eating food and delicacie...

  7. Ertong Zaoqi Jingxi Dongzuo Jineng yu Renzhi Fazhan de Guanxi

    DEFF Research Database (Denmark)

    Geng, Da; Zhang, Xingli; Shi, Jiannong

    2015-01-01

    Fine motor skills refer to any movement where an individual uses the small muscles or muscle areas of the hands and fingers; these movements serve to development of muscle while also improving the cognitive recognition of the object. Automatic fine motor skills can save limited attention resources...... for advanced cognition tasks as required by an individual; in the development of fine motor skills and cognition, the two abilities interact, some motor skills are the prerequisite for some cognition and the practice of cognition. Fine motor skills also can predict the academic performance of young students....... The two abilities are inter-related because they share common areas of the brain: the prefrontal lobe and the cerebellum. As a result, some cognition disorders could be treated through fine motor skill training and exercises....

  8. Meet Paris in Yu Xi's Documentaries

    Institute of Scientific and Technical Information of China (English)

    SuSan

    2004-01-01

    "This is a documenfary porlrayal of cultural celebrities.All the 60 interviewees have devoted themselves to the greal cause of China-France cultural exchange.Today,it is highly important to stress the preservation and promotion of cultural diversity and make

  9. Pseudo-istorija/arheologija i globalizacija: primer ex Yu prostora

    Directory of Open Access Journals (Sweden)

    Vesna Manojlović Nikolić

    2017-01-01

    Full Text Available U radu se diskutuje povezanost procesa globalizacije i pseudonaučnih tumačenja prošlosti. Istaknuta je dvostruka veza između efekata procesa globalizacije i pseudoistorijskog/pseudoarheološkog izmišljanja prošlosti. Prva je tendencija da se nezadovoljstvo kulturnom globalizacijom kompenzuje verovanjem u drugačiju i lepšu prošlost, dok se druga odnosi na upotrebu savremenih sredstava komunikacije u prenošenju pseudonaučnih tumačenja prošlosti širokoj javnosti. Pomoću primera sa područja bivše SFR Jugoslavije ukazano je da proces tranzicije ka globalnom društvu, koji se desio posle perioda eskalacije nacionalizama, doprinosi osećaju krize nacionalnih, regionalnih i lokalnih identiteta i prouzrokuje težnju ka stvaranju izmišljenih prošlosti. Takođe, skrenuta je pažnja da pseudoistoričari i pseudoarheolozi obilato koriste globalna sredstva masovne komunikacije, pre svega internet, čime njihova tumačenja postaju dostupna velikom broju ljudi i prete da postanu jedan od glavnih (iako zabludnih izvora za oblikovanje stavova o prošlosti i sadašnjosti.

  10. Transient Fanconi syndrome with severe polyuria and polydipsia in a 4-year old Shih Tzu fed chicken jerky treats.

    Science.gov (United States)

    Major, A; Schweighauser, A; Hinden, S E; Francey, T

    2014-12-01

    Acquired Fanconi syndrome is characterized by inappropriate urinary loss of amino acids, bicarbonate, electrolytes, and water. It has recently been described in dogs fed chicken jerky treats from China, a new differential diagnosis to the classical inciting infectious diseases (e.g. leptospirosis, pyelonephritis) and toxins. A dog fed exclusively chicken jerky treats purchased in Switzerland was presented to our clinic with severe polyuria, polydipsia and profound electrolyte and acid base disturbances. Other inciting causes of Fanconi syndrome were ruled out. The requirement of a very intensive supportive treatment in this dog stands in contrast to treatment of chronic forms of Fanconi syndrome as described in the Basenji. This intensive therapy and the associated monitoring can be a real challenge and a limiting factor for the prognosis of acquired Fanconi syndrome. Veterinarians should be aware of the risk of excessive feeding of chicken jerky treats.

  11. Chinese strategic culture, Shih and Li: a comparison of the Kuomintang and Chinese Communist Party from 1923-1927

    Science.gov (United States)

    2016-05-26

    contended that a time comes when “society can no longer live under this bourgeoisie , in other words, its existence is no longer compatible with society...said, “The first stage of revolution is the restriction of absolutism, which satisfies the bourgeoisie ; the second is the attainment of the republic...which satisfies the “people,” the peasantry and the petty bourgeoisie at large; the third is the socialist revolution, which alone can satisfy the

  12. Manufacture of Wood-Plastic Combinations by Use of Gamma Radiation; Fabrication de combinaisons bois-matiere plastique a l'aide des rayons gamma; Proizvodstvo drevesno-plastmassovykh sostavov s pomoshch'yu gamma-izlucheniya; Impregnacion de maderas con materiales plasticos en presencia de radiaciones gamma

    Energy Technology Data Exchange (ETDEWEB)

    Kent, J. A.; Winston, A.; Boyle, W.; Updyke, L. [Engineering Experiment Station, West Virginia University, Morgantown, West Virginia (United States)

    1963-11-15

    maderas de pino albar, encina blanca, encina roja, alamo, abedul, haya, abeto y arce sacarino. Se indica el efecto de la intensidad de dosis sobre las velocidades de polimerizacion en esas combinaciones, algunas de las cuales son incompatibles. Por ejemplo, la secoya no permite la polimerizacion del acetato de vinilo o del metacrilato de metilo, en tanto que el pino albar imposibilita la polimerizacion del acetato de vinilo. Los autores estudiaron diversos agentes de reticulacion con miras a determinar su eficacia para acelerar la polimerizacion y, con ello, conseguir ciclos mas breves, y exponen los resultados obtenidos para el acrilato de alilo, el dimetacrilato de etilenglicol, el dimetacrilato de polietilenglicol, el titanato de tetra-isopropilo, el metacrilato de alilo y (en el caso del estireno) el divinilbenceno. Los ensayos mecanicos realizados con maderas impregnadas ponen de manifiesto una mejora de propiedades tales como la dureza, el limite de elasticidad en la compresion y la estabilidad dimensional. Por lo general, se registra un aurpento de la fragilidad respecto de la madera natural. En la memoria se incluyen datos sobre la dureza, el limite de elasticidad en la compresion, la estabilidad en la compresion, la estabilidad dimensional, asi como la resistencia a la flexion y al cizallamiento. (author) [Russian] Opisan promyshlennyj metod polucheniya drevesno-plastmassovykh ''splavov'' s pomoshch'yu gamma-izlucheniya. Protsess sostoit iz dvukh chastej: propitki otobrannoj drevesiny neobkhodimym monomerom i polimerizatsii monomera v meste nakhozhdeniya .s pomoshch'yu gamma-luchej. Izucheno vliyanie razlichnykh faktorov na proniknovenie monomera v drevesinu. Provedennye ispytaniya pokazali, chto na praktike osushchestvimo khoroshee raspredelenie polimera v konechnom produkte. Odnu chast' obraztsov tolshchinoj 10 cm i dlinoj 150 cm podvergli propitke i issledovali na pronikanie monomera, v to vremya kak druguyu chast' obraztsov takoj zhe tolshchiny uspeshno

  13. The Radiation Induced Graft Copolymerization of Methacrylic Acid to Nylon; Copolymerisation par greffe de l'acide methacrylique sur le nylon, provoquee par irradiation; Obluchenie vyzyvaet graft-kopolimerizats yu metakrilovoj kisloty v nejlone; Injerto del acido metacrilico en el nylon por copolimerizacion radioinducida

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, R; Thomas, J K

    1960-07-15

    metakrilovoj kisloty v nejlon putem podgotovki k oblucheniyu. Skorost' prosachivaniya otnositel'no bol'she, chem skorost' komopolimerizatsii. Ne sushchestvuet prostoj svyazi mezhdu skorost'yu reaktsii i vsej dozoj. Temperaturnaya zavisimost' skorosti prosachivaniya v volokno, podgotovlennoe k oblucheniyu v vozdukhe, ukazyvaet, chto nachalo prosachivaniya, po-vidimomu, proiskhodit putem razlozheniya peroksidnykh grupp, obrazovannykh posle oblucheniya. Izmereniya ehlektricheskogo soprotivleniya na obluchennom volokne ukazyvayut, chto razlozhenie umen'shaetsya na koehffitsient 10. (author)

  14. Ultra-high performance liquid chromatography coupled with photo-diode array and quadrupole/time-of-flight mass spectrometry based chemical profiling approach to evaluate the influence of preparation methods on the holistic quality of Qiong-Yu-Gao, a traditional complex herbal medicine.

    Science.gov (United States)

    Xu, Jin-Di; Mao, Qian; Shen, Hong; Zhu, Ling-Ying; Li, Song-Lin; Yan, Ru

    2013-08-23

    Qiong-Yu-Gao (QYG), consisting of Rehmanniae Radix (RR), Poriae (PO) and Ginseng Radix (GR), is a commonly used tonic traditional complex herbal medicine (CHM). So far, three different methods have been documented for preparation of QYG, i.e. method 1 (M1): mixing powders of GR and PO with decoction of RR; method 2 (M2): combining the decoction of RR and PO with the decoction of GR; method 3 (M3): decocting the mixture of RR, GR and PO. In present study, an ultra-high performance liquid chromatography coupled with photo-diode array and quadrupole/time-of-flight mass spectrometry (UHPLC-PDA-QTOF-MS/MS) based chemical profiling approach was developed to investigate the influence of the three preparation methods on the holistic quality of QYG. All detected peaks were unambiguously identified by comparing UV spectra, accurate mass data/characteristic mass fragments and retention times with those of reference compounds, and/or tentatively assigned by matching empirical molecular formula with that of known compounds, and/or elucidating quasi-molecular ions and fragment ions referring to information available in literature. A total of 103 components, mainly belonging to ginsenosides, phenethylalcohol glycosides, iridoid glycosides and triterpenoid acids, were identified, of which 5 degraded ginsenosides were putatively determined to be newly generated during preparation procedures of QYG samples. Triterpenoid acids and malonyl-ginsenosides were detected only in M1 samples, while degraded ginsenosides were merely detectable in M2/M3 samples. The possible reasons for the difference among chemical profiles of QYG samples prepared with three methods were also discussed. It could be concluded that preparation method do significantly affect the holistic quality of QYG. The influence of the altered chemical profiles on the bioactivity of QYG needs further investigation. The present study demonstrated that UHPLC-PDA-QTOF-MS/MS based chemical profiling approach is efficient and

  15. San luo xuan mo xing ji qi liang hua fen zhi fang fa yan tao

    NARCIS (Netherlands)

    Ye, Y.; Leydesdorff, L.; Wu, Y.

    2014-01-01

    A discussed study on the Triple Helix with its quantitative analysis method. With brief introduction to background and progress of Triple-Helix(TH) researches, it is clarified that TH quantitative methodology focuses on the indicator of synergy (T) as reduction of uncertainty that can be shaped

  16. Tracer Experiments on Food Exchange in Ants and Termites; Emploi des radioindicateurs dans l'etude de la trophallaxis chez les fourmis et les termites; Izuchenie s pomoshch'yu indikatorov obmena pishchej u murav'ev i termitov; Empleo de indicadores radiactivos para estudiar la trofalaxia en las hormigas y los termites

    Energy Technology Data Exchange (ETDEWEB)

    Gosswald, K.; Kloft, W. [Institute of Applied Zoology, University of Wurzburg, Federal Republic of Germany (Germany)

    1963-09-15

    murav'i, medonosnye pchely i termity yavlyaetsya ikh stremlenie k trofollakticheskomu obmenu pishchej, kotoryj mokhet byt' khorosho izuchen s pomoshch'yu mechennoj radioaktivnymi veshchestvami pishchi. Pri sravnitel'nom izuchenii samaya vysokaya skorost' obmena byla obnaruzhena u medonosnykh pchel, v to vremya kak u razlichnykh podsemejstv murav'ev ona byla chrezvychajno raznoobraznoj, chto dolkhvo byt' uchteno pri provedenii polevykh ehksperimentov s primeneniem indikatorov. Samoe sil'noe stremlenie k trofollakticheskomu obmenu my obnaruzhili u podsemejstva Camponotlnae. Usilenno izuchalis' murav'i Genus Formica.osobenno Formica polyctena (Forst.), i rodstvennye poligennye i polycalous vidy, kotorye igrayut vakhnuyu rol' v predupreditel'noj biologicheskoj bor'be s nasekomymi-vreditelyami lesa. Ustanovleno, chto skorost' obmena pishchej v odnom muravejnike obuslovlena temperaturoj, vremenem, kolichestvom osobej i nasyshcheniem. Drugoj problemoj yavlyaetsya vopros o tom, sushchestvuet li obmen pishchej mekhdu razlichnymi muravejnikami kolonii murav'ev odnogo vida. Pometiv otdel'nye muravejniki s pomoshch'yu vneseniya radioaktivnoj pishchi, my smogli obnaruzhit' intensivnyj obmen pishchej mekhdu razlichnymi muravejnikami kolonii, otstoyashchimi drug ot druga na rasstoyanie do 200 m. Analogichnye rezul'taty my poluchili dlya trekh razlichnykh kolonij v razlichnye gody. Sushchestvovanie takogo dal'nego obmena pishchej yavlyaetsya ochen' vakhnym dlya otsenki reguliruptsego dejstviya poleznykh vidov murav'ev v otnoshenii nasekomykhvreditelej. Lelo v tom, chto obmen prepyatstvuet bystromu nasyshcheniyu populyatsii lyubogo muravejnika vsledstvie mestnoj massovoj invazii nasekomykh v ikh predydushchem gnezde. Kak pokazali ehksperimenty s primeneniem indikatorov, sobrannaya pishcha popadaet v bol'shinstvo okruzhayushchikh muravejnikov kolonii murav'ev. Poehtomu kolonii ehtikh poleznykh lesnykh murav'ev dejstvuyut kak slokhnaya sistema s vysokoj ehkologicheskoj ehffektivnost'yu. S

  17. Pulsed Neutron Studies of BeO-Natural Uranium Lattices; Etudes de Reseaux Uranium Naturel-Glucine, par la Methode des Neutrons Pulses; Issledovanie reshetok BeO-prirodnyj uran s pomoshch'yu impul'snykh nejtronov; Estudio de Reticulados de Beo-Uranio Natural con Ayuda de Neutrones Pulsados

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, B. V.; Nargundkar, V. R.; Subbarao, K. [Atomic Energy Establishment Trombay, Bombay (India)

    1965-10-15

    proporcional'nye schetchiki iz oboga- shhennogo trehftoristogo bora. Prostranstvennye i vremennye garmoniki byli ustraneny s pomoshh'ju metoda, opisannogo Dzhoshi i drugimi v 1965 godu. Postojannaja raspada osnov- nogo sostojanija opredelena dlja neskol'kih laplasianov pri sostojanii, dalekom ot kriti- cheskogo. V jetih vychislenijah prinimali v raschet jeffekt diffuzionnogo ohlazhdenija i ani- zotropii. Vse postojannye diffuzii i razmnozhenija opredeljali metodom approksimacii naimen'shih kvadratov tremja razlichnymi podhodami. Mgnovennyj kriticheskij laplasian opredelen putem razlozhenija uravnenija postojannoj raspada dlja {lambda} = 0 . Okonchatel'nymi re- zul'tatami javljajutsja: Diffuzionnaja dlina L = 15,2 sm. Postojannaja absorbcii {lambda}{sub 0} = 762,5 sek{sup -1} . Diffuzionnyj kojefficient D = 1,761 * 10{sup 5} sm{sup 2} sek{sup 1} . Postojannaja diffuzionnogo ohlazhdenija C = -8,766 * 10{sup 5} sm{sup 4} sek{sup -1}. Vozrast {tau} = 150,7 sm{sup 2}. Kojefficient neogranichennogo razmnozhenija k{sub {infinity}} = 1,126. Mgnovennyj kriticheskij laplasian V{sup 2} = 3,00 - 10{sup -4} sm{sup -2}. (author)

  18. Compounds Labelled with Low-Energy Gamma-Ray Emitters for Medical Isotope Scanning; Gammagraphie au Moyen de Composes Marques avec des Emetteurs Gamma de Faible Energie; Soedineniya, ispol'zuemye pri meditsinskom izotopnom skennirovanii, mechennye s pomoshch'yu gamma-izluchatelej nizkoj ehnergii; Compuestos Marcados con Emisores Gamma de Baja Energia para la Exploracion Medica Mediante Isotopos

    Energy Technology Data Exchange (ETDEWEB)

    Scheer, K. E.; Zum Winkel, K.; Georgi, M. [Czerny-Krankenhaus der Universitat Heidelberg, Federal Republic of Germany (Germany)

    1964-10-15

    por los tejidos del cuerpo limita la profundidad a que las lesiones pueden ser visualizadas. En organos de grandes dimensiones, como el higado, se evita la superposicion de las radiaciones procedentes de la parte posterior del organo, lo que permite detectar mejor las lesiones superficiales. El. emisor,gamma de baja energia mas importante es el {sup 125}I. Para la exploracion de la tiroides se utiliza en forma de yoduro. El Rosa Bengala marcada con {sup 125}I es un compuesto adecuado para la exploracion del higado. Tambien puede utilizarse albumina desnaturalizada por el calor, marcada con {sup 125}I. Para la exploracion del rinon se ha comprobado que el hipuran marcado con {sup 125}I da buenos resultados cuando se inyecta por via intramuscular con hialuronidasa a fin de lograr un nivel uniforme de radiactividad en este organo. Otro emisor gamma de baja energia muy util para la exploracion medica es el {sup 197}Hg que puede utilizarse en forma de cloruro para la exploracion de los rinones y el bazo. Deben tomarse precauciones especiales para evitar la superposicion del rinon y el bazo. La exploracion da mejores resultados si se utiliza {sup 197}Hg marcado con neohidrina. Este compuesto puede emplearse tambien para la localizacion de tumores del cerebro. Los autores presentan centelleogramas tipicos de tumores de la tiroides, del higado, del bazo, del rinon y del cerebro obtenidos con emisores gamma de baja energia y con nuclidos y compuestos tradicionales, y examinan las ventajas que ofrecen los primeros. (author) [Russian] Gammaizluchateli nizkoj jenergii imejut osobye preimushhestva pri ispol'zovanii ih dlja medicine - skogo scintilljacionnogo skennirovanija po dvum prichinam: 1. Svincovaja zashhita kollimatorov znachitel'no jeffektivnee. Pojetomu mozhno primenjat' tonkostennye kollimatory s mnogokratnoj fokusirovkoj, dobivajas' pri jetom naibol'shego geometricheskogo razreshenija, i v svjazi s jetim- vozmozhnosti obnaruzhenija nebol'shih porazhenij. 2. Pogloshhenie

  19. 原住民完全中學的實施現況與挑戰:以蘭嶼高級中學為例 The Implementation and the Challenges Involved in Indigenous Integrated Secondary Schools in Taiwan: A Case Study of Lan-Yu High School

    Directory of Open Access Journals (Sweden)

    張如慧Ju-Hui Chang

    2012-09-01

    Full Text Available 建立以原住民為主體,符合原住民需求的教育體系,是原住民社區本位教育的重要理念,而此理念亦納入我國的《原住民族教育法》中。本研究以全國第一所原住民完全中學―蘭嶼高級中學為例,進行個案研究,希望由原住民社區本位教育的理論觀點出發,瞭解在地師生及居民的經驗和想法,重新解讀該校在完全中學原訂目標上的實施現況,及其面臨的挑戰。研究時間為2007年8月至2008 年7月,蒐集資料的方法以師生和社區人士的訪談為主,並輔以部分時間的田野觀察。研究結果發現,蘭嶼成立完全中學的成效包括:提供最弱勢學生的升學和學習機會;透過完全中學經費的溢注,提高城鄉高中教育均衡發展的可能性;以及透過文化融入課程與相關活動,促進學校社區化等。然而因為社區和在地參與 仍有限,所以官方的政策或經費運用,無法完全符合當地真正的需求,更遑論激發社區對教育的主體性和能動性。 Indigenous community-based education argues that indigenous peoples are the subject of educational systems and institutions whose needs should be fulfilled. This concept is also reflected in Indigenous Education Law in Taiwan. This case study is based on the theory of indigenous community-based education and focuses on the first indigenous integrated secondary school in Taiwan, Lan-Yu High School, trying to understand the implementation of the school and the challenges it faced. The research was conducted from August 2007 to July 2008. Its data was collected through interviews with teachers, students, and community members, as well as by participant observation. The findings showed that the integrated secondary school improved educational equality for the most disadvantaged students, that the financial subsidies helped to promote balanced development of secondary education, and that

  20. Quality Selection of Zircaloy-2 Canning Tubes by Ultrasonic Testing on Small Defects; Controle de la Qualite des Gaines en Zircaloy-2: Detection de Petits Defauts par les Ultrasons; Achestvennyjotb ortrub chatykh obolochek iz tsirkalloya-2 putem vyyavleniya nebol'shikh defektov s pomoshch'yu ul'trazvuka; Control de Calidad de los Revestimientos de Zircaloy-2 por Localizacion Ultrasonica de Pequenos Defectos

    Energy Technology Data Exchange (ETDEWEB)

    Van Der Linde, A. [Reactor Centrum Nederland, Petten (Netherlands); Deraad, J. A. [Roentgen Technische Dienst N.V., Rotterdam (Netherlands)

    1965-09-15

    , de los 93 tubos ensayados, 21 presentaban defectos transversales de 10 a 50 {mu}m de profundidad. Por consiguiente, puede afirmarse que el procedimiento indicado permite clasificar los tubos con arreglo a su calidad. (author) [Russian] Trubchatye obolochki iz cirkalloja-2 s vnutrennim diametrom 10,20 mm, tolshhinoj stenok 0,90 mm i dlinoj 1500 mm, prednaznachennye dlja proverki v kachestve pokrytija toplivnyh sterzhnej pri temperature 330 Degree-Sign S v reaktornoj petle s vodoj pod davleniem ispytyvalis' s pomoshh'ju ul'trazvuka s cel'ju obnaruzhenija defektov. Ispytyvaemye trubchatye obolochki byli postavleny izgotoviteljami v SShA, soedinennom Korolevstve i v Skandinavii. Nashe trebovanie, chtoby vse postavlennye trubki byli svobodny ot treshhin i drugih defektov razmerom svyshe 500 - 1000 mikron po dline i svyshe 25 - 50 mikron po glubine, ne bylo prinjato polnost'ju izgotoviteljami. Oni mogli garantirovat' tol'ko otsutstvie treshhin velichinoj svyshe 1000 mikron po dline i svyshe 50 mikron po glubine. V svjazi s tem, chto iz 93 ispytannyh trub tol'ko u dvuh byli obnaruzheny treshhiny velichinoj svyshe 50 mikron po glubine, reshili provodit' bolee stroguju proverku, v rezul'tate kotoroj mozhno bylo by obnaruzhivat' defekty velichinoj porjadka 10 - 50 mikron po glubine. Dlja obnaruzhenija i registracii takih nebol'shih defektov primenjalos' poluavtomaticheskoe ul'trazvukovoe impul'snoe oborudovanie, dejstvujushhee kak v prodol'nom, tak i v poperechnom napravlenijah, v kombinacii s sistemami propuskanija i mnogokanal'nym registratorom. Sistema razvertki byla otregulirovana takim obrazom, chto vnutrennie i naruzhnye defekty odnogo i togo zhe porjadka i razmera ukazyvalis' s odinakovymi amplitudami. Kalibrovanie oborudovanija proizvodili na iskusstvennyh defektah. Defekty, obrazovavshiesja v prodol'nom napravlenii, obnaruzhivalis' s pomoshh'ju razdel'noj sistemy datchik-priemnik s primeneniem fokusirovannogo puchka. Defekty, obrazovavshiesja v poperechnom napravlenii

  1. Analysis of Scan Records with a Recording Densitometer - The ''Re-Scanner''; Etude d'un Grand Collimateur a Focalisation et Fort Pouvoir de Resolution: Resultats; Analiz skenogramm s pomoshch'yu registriruyushchego densitometra - ''re-skenner''; Diseno y Funcionamiento de un Gran Colimador Enfocado de Alto Poder de Resolucion

    Energy Technology Data Exchange (ETDEWEB)

    Harris, C. C.; Bell, P. R.; Satterfield, M. M.; Ross, D. A.; Jordan, J. C. [Oak Ridge National Laboratory, TN (United States)

    1964-10-15

    kontrastnosti. Porogovyj kontrol' d a et ljuboj ''sokrashhennyj uroven'' vybora. Rabota provoditsja bystro, i diagramma mozhet byt' reskennirovana v techenie nebol'shogo promezhutka vremeni, neobhodim ogo dlja poluchenija pervonachal'nogo izobrazhenija. Issledovanija v oblasti klinicheskogo skennirovanija pochti ljubogo organa ili rajona., predstavljajushhego interes, pokazyvajut, chto rerazvertyvatel' daet informaciju, ne vidimuju snachala na di agram mah pri pervonachal'nom skennirovanii. Jeto bylo osobenno poleznym pri opredelenii st atisticheskogo znachenija nebol'shih izmenenij v kojefficiente scheta pri skennirujushhem izobrazhenii. . Pri diagrammah, poluchennyh metodom skennirovanija, bol'shogo dinamicheskogo diapazo n a , gle nikakoj otdel'nyj sokrashhennyj urov en' udovletv orit el'no ne pokazy vaet vse rajony, predstavljajushhie interes, vnov' byli neobhodimy rerazvertyvateli na nekotoryh sokrashhennyh urovnjah. V popytke preodolet' je t u trudnost' ispol'zovalsja dvuhdiapazonnyj chuvstvitel'nyj jel em en t , kotoryj ohvatyvaet rajon registracii vokrug o bl a sti nabljudenija glavnogo chuvstvitel'nogo jel em en t a . Po krajnej m er e , vozmozhny tri vida jek s pluatacii pribora s dvuhdiapazonnym chuvstvitel'nym jelemen tom: 1) ''normal'naja'' je k s pluatacija; 2) ignorirovanie obshhej plotnosti izobrazhenija i reakcija tol'ko na nebol'shie izmenenija, ustanavlivaja takim obrazom svoj sobstvennyj sokrashhennyj uroven'; 3) soobshhenie tol'ko o vnezapnyh izmenenijah v plotnosti registracii. Po-vidimomu, vozmozhny takzhe drugie vidy. Jeto sravnitel'no prostoj i nedorogostojashhij pribor obespechivaet okazanie cennoj pomoshhi v interpretacii diagramm, proizvedennyh metodom skennirovanija. (author)

  2. Ultrasonic Water-Gap Measurements in MTR Fuel Elements; Mesure par Ultrasons des Espaces Intercalaires dans les Elements Combustibles des Reacteurs d'Essai de Materiaux; Izmereniya vodyanogo zazora v teplovydelyayushchikh ehlementakh dlya materialovedcheskogo reaktora s pomoshch'yu ul'trazvuka; Medicion Ultrasonica de la Capa de Agua en Elementos Combustibles para Reactores de Ensayo de Materiales

    Energy Technology Data Exchange (ETDEWEB)

    Deknock, R. [Metallurgy Department, S.C.K./C.E.N., Mol (Belgium)

    1965-10-15

    en un convertidor tiempo-tension con circuitos logicos transistorizados. El instrumento permite un ajuste continuo del cero para cualquier espesor-arbitrario de la capa de agua entre 2 y 4 mm, con lo cual posibilita un registro con el cero en el centro de la escala. Ademas, cualquier intervalo deseado de 100 {mu}m puede dar una tension estable de 1 V a la salida para accionar un registrador. Se puede medir facilmente cualquier variacion en el espesor del agua con una precision de 5 {mu}m. Se han medido con este metodo varios elementos combustibles, y los resultados y la reproducibilidad fueron muy satisfactorios. (author) [Russian] Sil'nye potoki teplo- vyh nejtronov, kotorye obychno voznikajut v novejshih reaktorah dlja ispytanija materialov, javljajutsja podhodjashhim s r e d s t v om ravnomernoj teploperedachi i nadezhnogo otvoda tepla, s pomoshh'ju kotorogo mozhno izbezhat' obrazovanija para v bol'shih ob{sup e}mah. Krome togo, v celjah kontrolja nad obshhim raspuhaniem i povedeniem reaktornogo topli- va izmerjajut vodjanoj zazor pri jeksperimentah posle obluchenija s otrabotannymi teplovy- deljajushhimi jelementami. S jetoj cel'ju byl razrabotan zond dlja izmerenija 3 - m m vodjanogo zazora teplovydeljaju- shhego jelementa ispytatel'nogo reaktora BR-2 dlinoj bolee 1 m , v osnovu kotorogo polozhen princip ul'trazvuka. Pri jeksperimentah posle obluchenija izmeritel'nyj zond dolzhen dej- stvovat' v teplovydeljajushhem jelemente, pogruzhennom v bassejn na glubinu ne menee 6 m . Zond mozhet vyderzhat' pogruzhenie v vodu prodolzhitel'nyj period vremeni, i on ne podver- gaetsja vozdejstviju obychnyh doz gamma-obluchenija. Hotja sistema dejstvuet na osnove obychnogo metoda otrazhenija impul'sov, ona pozvo- ljaet razdeljat' ispuskaemye i otrazhennye impul'sy s pomoshh'ju 10 Mgc ferrojelektriches- kogo kristalla, kotoromu svojstvenno bol'shoe rassejanie jenergii. Mozhno ispol'zovat' zapis' pokazanij oscilloskopa, v kotorom vremja registriruetsja na gorizontal'noj osi

  3. The Determination of Components of Radioactive Decay Mixtures by Computer Analysis of Count-Rate Data; Determination des Composants de Melanges Radioactifs en Decroissance par Analyse a l'Ordinateur des Resultats du Comptage; Opredelenie komponentov smesej radioaktivnogo raspada posredstvom analiza dannykh skorostej scheta s pomoshch'yu schetno-reshayushchego ustrojstva; Determinacion de los Componentes de Mezclas Radiactivas por Analisis de los Datos de Recuento Mediante Calculadoras

    Energy Technology Data Exchange (ETDEWEB)

    Airman, W. D.F.; Tyler, S. A.; Dipertand, M. H.; Sedlet, J. [Argonne National Laboratory, Argonne, IL (United States)

    1965-10-15

    izmenjaetsja znachitel'nym obrazom za period vremeni nabljudenija, libo v rezul'tate neposredstvennogo raspada, libo vsledstvie narastanija produktov raspada. Dlja kazhdoj novoj smesi predstavljaetsja vozmozhnym predskazat' sostav vozmozhnyh komponentov na osnovanii takih soobrazhenij, kak proishozhdenie i posledujushhaja jevoljucija smesi, harakter himii otdelenija i metod ili metody scheta. Esli takogo roda soobrazhenija primenjajutsja nadlezhashhim obrazom, to sostav vozmozhnyh komponentov vkljuchit vse dejstvitel'nye komponenty smesi. V takom sluchae mozhno sostavit' nadlezhashhie uravnenija narastanija i raspada i reshit' ih odnovremenno dlja poluchenija kazhdogo komponenta, ili zhe smes' mozhet byt' razlozhena na sostavnye chasti graficheski putem jekstrapoljacii linejnyh otrezkov krivoj obshhego raspada i narastanija. Odnako v sluchae bol'shogo chisla komponentov, esli rech' idet o kompleksnyh shemah raspada, jeti dva metoda libo okazyvajutsja nepriemlemymi, libo ne predstavljaetsja vozmozhnym opredelit' velichiny pogreshnostej, svjazannyh s vychislenijami. Otbor komponentov raspada po metodu naimen'shih kvadratov daet luchshuju ocenku, chem samo po sebe odnovremennoe reshenie uravnenij. Pojetomu na osnovanii metoda naimen'shih kvadratov byla vyrabotana programma po fortranu dlja schetno-reshajushhego ustrojstva (oboznachennaja po kodu {sup K}ORD{sup )}, kotoraja razreshaet sledujushhuju obshhuju problemu: zadajutsja momenty vremeni i otschety za edinicu vremeni dlja proby, vozmozhnye ishodnye radioizo- ' topy i shemy ih raspada, a takzhe vse sootvetstvujushhie konstanty raspada i jeffektivnosti obnaruzhenija; trebuetsja podschitat' kolichestvo kazhdogo ishodnogo izotopa, dejstvitel'no prisutstvujushhego v zaranee opredelennoe nulevoe vremja. V dopolnenie k jetomu programma daet kolichestvo ishodnyh i dochernih produktov v ljuboj moment registracii dannyh. Ispol'zovannaja pervonachal'no dlja bioanalizov i dlja analiza vzjatyh iz okruzhajushhej sredy prob, jeta programma

  4. Excitation of Neutron Waves by Modulated And Pulsed Sources; Excitation d'Ondes Neutroniques au Moyen de Sources Modulees et Pulsees; Vozbuzhdenie nejtronnykh voln s pomoshch'yu modulirovannykh i impul'snykh istochnikov; Excitacion de Ondas Neutronicas Mediante Fuentes Moduladas y Pulsadas

    Energy Technology Data Exchange (ETDEWEB)

    Perez, R. B.; Booth, R. S. [University of Florida, Gainesville, FL (United States)

    1965-10-15

    jadernyh svojstvah, predstavljajushhih interes. Pri provedenii jeksperimentov v kachestve zamedlitelja ispol'zovali grafit. Ispol'zovali dva razlichnyh istochnika teplovyh nejtronov. V odnom sluchae nejtrony s jenergiej 14 Mjev, poluchennye s pomoshh'ju uskoritelja Kokrofta-Uoltona, byli termalizovany v bake, soderzhashhem neskol'ko sloev zheleza, svinca i grafita, pogruzhennyh v vodu. Pozdnee s po* moshh'ju imejushhegosja vo Floridskom universitete uskoritelja Van de Graafa moshhnost'ju 4 Mjev byli polucheny nejtrony s jenergiej 29 kjev iz reakcii ( Li -r) , kotorye byli termalizovany v neskol'kih djujmah parafina. V oboih sluchajah ionnye puchki mogli byt' sinusoidal'no modulirovannymi ili pul'sirujushhimi. Rezul'taty analiza Fur'e, provedennogo s medlennymi impul'sami, prekrasno soglasujutsja s rezul'tatami, poluchennymi pri sinusoidal'nom vozbuzhdenii voln. Issleduemye chastoty byli v diapazone ot nulja do 1200 gc. V rezul'tate aproksimacii jeksperimental'nyh dannyh sposobom naimen'shih kvadratov s primeneniem uravnenij (4) i (5) byli polucheny sledujushhie rezul'taty: B{sup (0)} = B{sup 2}{sub Up-Tack} + a{sub 1}/L{sub 0} = (6.6 {+-} 0.1) 10{sup -3} (cm{sup -2}) (4) B{sup (1)} = a{sub 2}/D{sub 0} = (4.38 {+-} 0.2) 10{sup -6} (cm{sup -2}) (5) B{sup (2)} = {Sigma}{sub {gamma}} H{sub 0{gamma}}/ Empty-Set {sub {gamma}{gamma}} = (2.5 {+-} 0.2) 10{sup -10} ({gamma} = 0, 1, 2, .....10) (6) B{sup 2}{sub Up-Tack} = poperechnyj laplasian (cm{sup -2}) = 5.96 x 10{sup -3} cm{sup -2} otnosjatsja k matrichnym jelementam diffuzionnyh i termalizacionnyh operatorov. S pomoshh'ju uravnenija (5) opredeleno, chto znachenie D{sub 0} = (2.2 {+-} 0.1) x 10{sup 5} cm{sup 2}/sek-l soglasuetsja s obychnymi izmerenijami impul'snyh nejtronov (5). Teoreticheskie raschety s ispol'zovaniem razlichnyh modelej jadra takzhe soglasujutsja s jeksperimental'nymi rezul'tatami. (author)

  5. Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor

    OpenAIRE

    Wang G; Li L; Liu B; Han X; Wang CH; Wang JW

    2018-01-01

    Guang-Yu Wang,1,* Ling Li,2,* Bo Liu,1 Xiao Han,1 Chun-Hua Wang,1 Ji-Wen Wang3 1Department of Neurosurgery, 2Department of Pediatrics, Qilu Children’s Hospital of Shandong University, Jinan, Shandong, 3Department of Neurology, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Pudong New District, Shanghai, People’s Republic of China *These authors contributed equally to this work Purpose: This study aimed to explore significant gene...

  6. Enhanced immunization via dissolving microneedle array-based delivery system incorporating subunit vaccine and saponin adjuvant

    OpenAIRE

    Zhao,JiHui; Zhang,Qi-Bo; Liu,Bao; Piao,Xiang-Hua; Yan,Yu-Lu; Hu,Xiao-Ge; Zhou,Kuan; Zhang,Yong-Tai; Feng,Nian-Ping

    2017-01-01

    Ji-Hui Zhao,1,* Qi-Bo Zhang,1,* Bao Liu,2 Xiang-Hua Piao,1 Yu-Lu Yan,1 Xiao-Ge Hu,1 Kuan Zhou,1 Yong-Tai Zhang,1 Nian-Ping Feng1 1School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Anethesiology Department, Augusta University, Augusta, GA, USA *These authors contributed equally to this work Purpose: To enhance the immunogenicity of the model subunit vaccine, ovalbumin (OVA) was combined with platycodin (PD), a ...

  7. Pedagogical Challenges in Folk Music Teaching in Higher Education: A Case Study of Hua'er Music in China

    Science.gov (United States)

    Yang, Yang; Welch, Graham

    2016-01-01

    Recent literature suggests that traditional approaches in folk music education are not necessarily compatible with the pedagogical conventions of formal music education. Whilst several recent studies have tended to define these non-classical-music learning contexts as "informal", the practice of folk music that was recently introduced…

  8. Indigenous Communities and Cross­Strait Rapprochement: A Case Study of Chun­-ri and Shih-­wen

    Directory of Open Access Journals (Sweden)

    Andi Kao

    2015-08-01

    Full Text Available Absent from most public debates on Taiwan’s embrace of neoliberal capitalism are the potential consequences of economic liberalization for Taiwan’s indigenous peoples. Deregulating markets and unfettering capital and resources are tied inextricably with cross-Strait politics. With a deep-seated apprehension of China still felt in many corners of the Taiwanese society, these issues are often framed with particular emphasis on the “China Factor”, overshadowing other relevant economic and societal considerations and thereby narrowing the scope of debate over government policies. Nevertheless, the potential influx of foreign capital investment, long- and short-term migrant labor and international visitors may have profound effects on Taiwan’s most vulnerable citizens, including the indigenous peoples. This paper will report the results of field research conducted among the Paiwan ethnic group, assessing actual and potential future changes affecting their individual families and communities. Preliminary assessment indicates that official policies liberalizing visitation and trade between China and Taiwan have already affected the Paiwan communities. Whether these changes become handicaps or opportunities depends on realistic evaluation, strategic planning, education, implementation, and periodic re-evaluation. This paper will contribute to the larger discussion of possible responses to the effects of inter-regional migration and transformations on minority societies by providing an assessment of current and potential conditions among the Paiwan of Taiwan.

  9. The use of 113mIn-MAA infusion lung imaging in treatment of C. O. P. D with 'invigorating the circulation of blood and reducing stasis' method for observing therapeutic effectiveness

    International Nuclear Information System (INIS)

    Zhang Qinghua; Guo Yiqin; Li Zhuanfu

    1990-01-01

    In this study 100 cases of C. O. P. D were classified according to dialectical method of traditional Chinese Medicine. By infusion lung imaging it was shown that 76 cases were abnormal in blood supply in which the category of 'fei xin qi xu' ('weak in heart and lung breath') got the first place and followed by the category of II order 'fei qi xu' ('weak in lung breath'). It was considered that the change in lung infusion imagings were the evidence of 'fei xu zheng' ('weak-lunged symptom') 'xin xue yu zu' ('stasis of heart blood') and might be used to guide the treatment and to observe the efficiency of 'huo xue hua yu' ('invigorating blood circulation and eliminating stasis') therapy

  10. Chuancheng yu gengxin: Liu Mei sheng yu Minguo shiqi de shixue%传承与更新:留美生与民国时期的史学

    Institute of Scientific and Technical Information of China (English)

    李春雷

    2008-01-01

    @@ As it has long been acknowledged that historians do not simply write objectivehistories, but are themselves products of Specific times and places, there is littlequestion that histories of historiography can provide important insights. ProfessorLi Chunlei, of Tianjin Polytechnic University, contributes to our understandingof the origins of the modem discipline of history in China by focusing on theimportant role of returned students from the U.S. in fostering its developmentand shaping its direction.

  11. Feng xian tai du yu jiao yu he zhi ye xuan ze xing wei: yi ge shi yan fang fa de yan jiu an li

    NARCIS (Netherlands)

    Ding, X.; Sun, Y.; Hartog, J.

    2009-01-01

    An experimental study on risk attitude and choice behavior of education and career This paper introduces a research on risk attitude and choice behavior of education and career. Using the experimental methods, this study focuses on testing the reliability and validity of risk attitude measurement.

  12. VizieR Online Data Catalog: Chemical properties of red MSX sources (RMSs) (Yu+, 2016)

    Science.gov (United States)

    Yu, N.; Xu, J.

    2017-05-01

    Our molecular line data come from the Millimetre Astronomy Legacy Team Survey at 90GHz (MALT90) (e.g., Foster+ 2011, J/ApJS/197/25; Jackson+ 2013PASA...30...57J). This project is performed with Mopra, a 22m single-dish radio telescope located near Coonabarabran in New South Wales, Australia. The angular resolution of Mopra is 38", with a beam efficiency between 0.49 at 86GHz and 0.42 at 115GHz. The pointing accuracy of the main MALT90 maps is about 8", and the absolute flux uncertainty is in the range of 10%-17% depending on the transition in question. The target clumps of this survey are selected from the 870um Atacama Pathfinder Experiment (APEX) Telescope Large Area Survey of the Galaxy (ATLASGAL; Schuller+ 2009A&A...504..415S; Contreras+ 2013, J/A+A/549/A45; superseded by J/A+A/568/A41). Using Australia Telescope Compact Array (ATCA), Urquhart+ (2007, J/A+A/461/11) observed radio emissions of 826 Red Midcourse Space Experiment (MSX) Sources (RMSs) in the southern sky. We also have checked our sources with the data taken from the Sydney University Molonglo Sky Survey (SUMSS) carried out at 843MHz with the Molonglo Observatory Synthesis Telescope (MOST; Mauch+ 2003, VIII/81). See section 2 for further explanations. (5 data files).

  13. Yu-Shiba-Rusinov states in phase-biased superconductor-quantum dot-superconductor junctions

    DEFF Research Database (Denmark)

    Kirsanskas, Gediminas; Goldstein, Moshe; Flensberg, Karsten

    2015-01-01

    supercurrent, and the differential conductance as measured by a normal-metal tunnel probe. In absence of a phase difference only one linear combination of the superconductor lead electrons couples to the spin, which gives a single YSR state. With finite phase difference, however, it is effectively a two...

  14. A New Book: Minnegulov Kh.Yu. Kazan-Tatar Turkological School

    Directory of Open Access Journals (Sweden)

    A.V. Aksanov

    2016-12-01

    Full Text Available This book describes the history and current state of the Kazan-Tatar Turkological school. Its author analyzes the development of global and domestic Turkology, points out interrelations between various academic centers and specifies the convention of their separation. According to him, the Tatars played a significant role in the development of the Russian Oriental studies, since already from the 18th century, they collaborated with leading Russian Orientalists. The establishment of the University of Kazan in 1804 was a milestone in the development of Kazan School of Turkic Studies. The 1820–50s were a time of the highest development of Oriental studies in the University of Kazan. In addition to personnel training, the University created textbooks, dictionaries, scholarly works, collected manuscripts and established extensive international contacts. Soviet and modern periods were mainly related to the development of the historical and philological direction within the walls of educational institutions and the University of Kazan. In 2011, their Tatar faculties were united into the Institute of Philology and Arts of Kazan Federal University. Formation and development of the history of Tatar literature as an independent branch of literary science became one of the most important achievements of this stage. Great work on the collection, publication and study of Tatar folklore done in the last century was another important achievement.

  15. *Corresponding author. E-mail: m_ghaedi@mail.yu.ac.ir

    African Journals Online (AJOL)

    a

    content in real samples such as tap water, wastewater and a synthetic water sample ... KEY WORDS: Copper(II), Solid phase extraction, Activated carbon, Flame atomic ... ability to adsorb organic compounds and organic metal complexes as ...

  16. Complete genome sequence of Calditerrivibrio nitroreducens type strain (Yu37-1T)

    Energy Technology Data Exchange (ETDEWEB)

    Pitluck, Sam [Joint Genome Institute, Walnut Creek, California; Sikorski, Johannes [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Zeytun, Ahmet [Los Alamos National Laboratory (LANL); Lapidus, Alla L. [Joint Genome Institute, Walnut Creek, California; Nolan, Matt [Joint Genome Institute, Walnut Creek, California; Lucas, Susan [Joint Genome Institute, Walnut Creek, California; Hammon, Nancy [Joint Genome Institute, Walnut Creek, California; Deshpande, Shweta [Joint Genome Institute, Walnut Creek, California; Cheng, Jan-Fang [Joint Genome Institute, Walnut Creek, California; Tapia, Roxanne [Los Alamos National Laboratory (LANL); Han, Cliff [Los Alamos National Laboratory (LANL); Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Liolios, Konstantinos [Joint Genome Institute, Walnut Creek, California; Pagani, Ioanna [Joint Genome Institute, Walnut Creek, California; Ivanova, N [U.S. Department of Energy, Joint Genome Institute; Mavromatis, K [U.S. Department of Energy, Joint Genome Institute; Pati, Amrita [U.S. Department of Energy, Joint Genome Institute; Chen, Amy [Joint Genome Institute, Walnut Creek, California; Palaniappan, Krishna [Joint Genome Institute, Walnut Creek, California; Hauser, Loren John [ORNL; Chang, Yun-Juan [ORNL; Jeffries, Cynthia [Oak Ridge National Laboratory (ORNL); Detter, J. Chris [Joint Genome Institute, Walnut Creek, California; Brambilla, Evelyne-Marie [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Ngatchou, Olivier Duplex [HZI - Helmholtz Centre for Infection Research, Braunschweig, Germany; Rohde, Manfred [HZI - Helmholtz Centre for Infection Research, Braunschweig, Germany; Spring, Stefan [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Goker, Markus [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Woyke, Tanja [Joint Genome Institute, Walnut Creek, California; Bristow, James [Joint Genome Institute, Walnut Creek, California; Eisen, Jonathan [Joint Genome Institute, Walnut Creek, California; Markowitz, Victor [Joint Genome Institute, Walnut Creek, California; Hugenholtz, Philip [U.S. Department of Energy, Joint Genome Institute; Kyrpides, Nikos C [Joint Genome Institute, Walnut Creek, California; Klenk, Hans-Peter [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Land, Miriam L [ORNL

    2011-01-01

    Calditerrivibrio nitroreducens Iino et al. 2008 is the type species of the genus Calditerrivibrio. The species is of interest because of its important role in the nitrate cycle as nitrate reducer and for its isolated phylogenetic position in the Tree of Life. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the third complete genome sequence of a member of the family Deferribacteraceae. The 2,216,552 bp long genome with its 2,128 protein-coding and 50 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

  17. Yu šien yuan cha dzu czha t šia lie kutí

    Czech Academy of Sciences Publication Activity Database

    Chen, W.; Křížek, Michal

    2009-01-01

    Roč. 39, č. 15 (2009), s. 159-194 ISSN 1000-0984 R&D Projects: GA AV ČR(CZ) IAA100190803 Institutional research plan: CEZ:AV0Z10190503 Keywords : uniform partition * superconvergence * Céa's lemma Subject RIV: BA - General Mathematics

  18. Tong and Yu et al., Afr J Tradit Complement Altern Med. (2016) 13(1 ...

    African Journals Online (AJOL)

    PROF ADEWUNMI

    Serial dilution was undertaken using sterile distilled water and the inoculated normal saline. ... A multiple disc containing the antibiotics was placed on the surface of the agar. The multi ... sanitary risk there may be by hand contact with patients.

  19. Xinjiang Keji Rencai dui Chuangxin Huanjin de Neiyin Pingjia Moxing Goujian yu Shizheng Yanjiu

    DEFF Research Database (Denmark)

    Tan, Chunping; Tang, ChaoYing; Jiannong, Shi

    2015-01-01

    Innovation environment is the key factor to give full play to the dynamic role of the scientific talents. The article has investigated and analyzed the environmental factors and the degree of satisfaction of Xinjiang scientific talents in innovation activities by implicit theory, and structured...

  20. Analysis of Psychological Growth of the Main Character in Chenlun by Yu Dafu

    Directory of Open Access Journals (Sweden)

    Xuc Lin

    2008-05-01

    Full Text Available Article discusses the psychological aspect of the main character in the novel “Chen Lun”. The feelings of inferiority and loneliness are his initial mental states. The latter is caused by two factors: the social and personality factors while the former is caused by the political condition in China at that time and the fact that the Japanese underestimate the Chinese people. The writer uses Freud’s theory on the structure of personality and conflict, anxiety, and the defense mechanism to analyze the process of the psychological development of the main character. In the end of the story, the main character commits suicide since “he” cannot only solve the problem of his loneliness and inferiority but also he feels guilty of his wrongdoing which crushes his-ideal-self. The guilty feeling haunts him in such a way that he even denies himself.

  1. Ozhirenie sredi bol'nykh, obrativshikhsya za meditsinskoy pomoshch'yu (dannye krupnogo otechestvennogo epidemiologicheskogo issledovaniya

    Directory of Open Access Journals (Sweden)

    2009-06-01

    Full Text Available Research objective: to study obesity among 10541 patients in therapeutic, neurologik and cardiologikal practices in 29 cities of the Russian Federation from St.-Petersburg to Vladivostok (COMPASS program. All patients are divided on two groups: with obesity (average BMI=33,7+4,1 kg/m2, and without this disease (average BMI=24,4+3,0 kg/m2. Groups were compared under demographic characteristics; features of a medical route; somatic and mental state. 20% from all patients in mentioned practices in various cities of Russia have obesity. Patients with obesity are predominantly women (middle age 54,0+12,0 year. For these patients low social and economic status (with low educational level, absence of employment, loneliness etc. are characteristic. Patients with obesity are more often observe in cardiological practice. They suffer from cardiovascular diseases and type 2 diabetes. The hypothesis about obesity formation within mental disorders (depression, food addiction - dependence on food is presented. Possibility of treatment of patients with the help of sibutramine is discussed.

  2. Yu et al., Afr J Tradit Complement Altern Med., (2017) 14 (6): 1-9

    African Journals Online (AJOL)

    MC SYSTEM

    10.21010/ajtcam.v14i6.1. 1 .... Sigma-Aldrich Chemical Co. (St. Louis, MO, USA). Bornyl acetate ... For the precision of the developed method, the prepared samples were analyzed for six replicates within one day, and calculated relative standard ...

  3. Yu et al., Afr J Tradit Complement Altern Med. (2013) 10(6):551-554 ...

    African Journals Online (AJOL)

    cadewumi

    the cell survival rate was calculated according to the following formula: Cell survival rate = (OD value of the experimental group - OD value of the blank control group) / (OD value of the control group - OD value of the blank control group) x 100%. Four replicate wells were set up for each concentration at each time point, the ...

  4. Multi-channel recording of a pulse spectrum on the screen of a Williams tube used with a ferrite memory analyser; Enregistrement du spectre d'impulsion sur l'ecran d'un tube de Williams au moyen d'un analyseur multicanal a memoire en ferrite; Zapis' spektra impul'sov na ehkrane ehlektronno-luchevoj trubki mnogokanal'nogo analizatora s ferritovoj pamyat'yu; Registro multicanal del espectro de los impulsos en la pantalla del tubo electronico, en un analizador con memoria de ferrita

    Energy Technology Data Exchange (ETDEWEB)

    Rumler, Shtirad [Institut Yadernogo Issledovannya Chekhoslovatskoj Akldemii Nauk, Rzhezh Chekhoslovatskaya Sotsialisticheskaya Respublika (Czech Republic)

    1962-04-15

    promedio de impulsos es reducido. La causa reside en el dispositivo descifrador de la informacion leida en el canal directamente a partir de los circuitos sumadores y de los circuitos direccionales con registro inmediato en la pantalla. La ineptitud del registro inmediato es debida al bajo promedio y al tiempo estadistico de distribucion de los impulsos. El dispositivo propuesto resulta mas eficaz en este caso porque la calidad del registro no depende de la forma del espectro ni de la velocidad del recuento de los impulsos. Se utiliza este dispositivo en un analizador de 256 canales con una memoria de ferrita cuyo tiempo muerto es igual a 15 {mu}s. Los ciclos de la representacion oscilografica alternan periodicamente, con una frecuencia de repeticion de 50 Hz, con el ciclo de analisis del espectro medido. El tiempo de inscripcion del oscilografo es aproximadamente igual a 4 ms, es decir, un 20 por ciento de la duracion ordinaria del ciclo de trabajo del analizador. En analizadores cuyo numero de canales es menor y el tiempo muerto de memoria es mas corto, el tiempo del registro oscilografico representa apenas un pequeno porcentaje de la duracion del ciclo de. trabajo del analizador. (author) [Russian] V doklade budet opisana blok-skhema programmnykh tsepej, pozvolyayushchikh osushchestvlyat' mnogokanal'nuyu zapis' vozrastayushchego spektra anali- ziruemykh IMPUL'SOV na ehkrane ehlektronno-luchevoj trubki, v kombinatsii so staticheskoj ferritovoj pamyat'yu. Obshcheprinyatye sposoby neposredstvennoj zapisi na ehlektronno-luchevoj trubke yavlyayutsya v nekotorykh sluchayakh nesovershennymi v analizatorakh ukazannogo tipa. Zapis' okazyvaetsya nedostatochno chetkoj osobenno pri analize vremennykh ''kaskadov'' impul'sov s nizkoj chastotoj povtoreniya i s nizkim srednim chislom impul'sov. Prichinoj yavlyaetsya deshifrovka otchityvaemoj informatsii v kanale pryamo iz summiruyushchikh tsepej i iz adresnykh tsepej s neposredstvennoj zapis'yu na ehkrane. Neprigodnost

  5. Contemporary Challenges in Learning and Teaching Folk Music in a Higher Education Context: A Case Study of Hua'er Music

    Science.gov (United States)

    Yang, Yang; Welch, Graham

    2014-01-01

    Literature reviews suggest that traditional approaches in folk music education are not necessarily compatible with the conventions of formal music education. Whilst many recent studies have tended to define these non-classical music learning contexts as "informal", the practice of folk transmission music appears to be much more complex…

  6. Re ‘Luminescence dating of K-feldspar from sediments: a protocol without anomalous fading correction’ by Bo Li and Sheng-Hua Li

    DEFF Research Database (Denmark)

    Thomsen, Kristina Jørkov; Murray, Andrew; Jain, Mayank

    2012-01-01

    Have recently proposed a new measurement procedure (MET-pIRIR) for luminescence dating using feldspar; they argue that this procedure reduces anomalous fading to negligible levels, and that it is a significant improvement over existing protocols (pIRIR290). Here we compare the measured equivalent...

  7. Gene therapy for cartilage and bone tissue engineering

    CERN Document Server

    Hu, Yu-Chen

    2014-01-01

    "Gene Therapy for Cartilage and Bone Tissue Engineering" outlines the tissue engineering and possible applications of gene therapy in the field of biomedical engineering as well as basic principles of gene therapy, vectors and gene delivery, specifically for cartilage and bone engineering. It is intended for tissue engineers, cell therapists, regenerative medicine scientists and engineers, gene therapist and virologists. Dr. Yu-Chen Hu is a Distinguished Professor at the Department of Chemical Engineering, National Tsing Hua University and has received the Outstanding Research Award (National Science Council), Asia Research Award (Society of Chemical Engineers, Japan) and Professor Tsai-Teh Lai Award (Taiwan Institute of Chemical Engineers). He is also a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and a member of the Tissue Engineering International & Regenerative Medicine Society (TERMIS)-Asia Pacific Council.

  8. FY 1999 Report on overseas geological structure surveys. Joint Japan-China Yu Xian exploitation project (Attachments); 1999 nendo kaigai chishitsu kozo nado chosa futai shiryo. Nippon Chugoku sekitan kyodo tansa Yu Xian project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This reports provides the attachments for the report JN0041264. The contents include (1) minutes of the fourth steering committee, (2) technical reports presented to the fourth steering committee (I: report on FY 1998 joint exploitation works, and II: report on FY 1999 joint exploitation works), (3) minutes of the fifth steering committee, and (4) technical reports presented to the fifth steering committee (I: report on FY 1999 joint exploitation works, and II: report on planned FY 2000 joint exploitation works). The item (1) includes approval of the reports on FY 1998 and 1999 joint exploitation works. The item (2)-I report includes seismic exploitation test works, observation work results and quality evaluation thereof; drilling exploitation work results, quality evaluation thereof, exploitation results and evaluation thereof; exploitation results and evaluation thereof; and proposals. The item (2)-II report includes seismic exploitation, drilling exploitation, and man-hours of the workers from the both countries. The item (3) includes approval of the reports on FY 1999 joint exploitation works and planned FY 2000 joint exploitation works. The (4)-I report includes seismic exploitation work results and evaluation thereof, seismic exploitation test works, drilling exploitation work results, quality evaluation thereof, exploitation results and evaluation thereof, and proposals for the future works. The (4)-II report includes seismic and drilling exploitation plans, and numbers and periods of the workers from the both countries. (NEDO)

  9. About the article by M.A. Goncharov, Yu.N. Raznitsin, Yu.V. Barkin «SPECIFIC FEATURES OF DEFORMATION OF THE CONTINENTAL AND OCEANIC LITHOSPHERE AS A RESULT OF THE EARTH CORE NORTHERN DRIFT»

    Directory of Open Access Journals (Sweden)

    Yuri G. Leonov

    2012-01-01

    Full Text Available The review summary states that studies of the hierarchical subordination of geodynamic systems is top in the scientific agenda, and researches of orientation of the Earth’s surface deformation structures in relation to the elements of the stress field are important. It is noted that the proposed classification of geological objects by ranks is ambiguous, and there is a need for a geodynamic model to provide a basis for studying relationships between the fields of forces, stresses and strains on the surface and processes which take place deep in the core and mantle of the Earth.

  10. Response to Dr Yu's paper: A survey of radon properties in underground railway stations in Hong Kong

    International Nuclear Information System (INIS)

    Frommer, G.

    1996-01-01

    This letter criticizes the results of a radon survey performed in underground railway stations in Hong Kong. The authors of the survey concluded that the radon dose received by the night time maintenance worker is not insignificant. However, it is the opinion of the Mass Transit Railway Corporation that this radon dose value is at best a crude estimate based on a limited number of non-representative short-term radon measurements. (UK)

  11. «The Light Thaw» at times of P.Yu. Shelest: myth or reality?

    Directory of Open Access Journals (Sweden)

    V. V. Ivanenko

    2016-06-01

    The central point of the issue is the phenomenon of «ukrainofilstvo» (the utmost love to Ukraine, which this outstanding but controversial official kept to. We specifically study the essence, components and consequences of the historical process known as «the light thaw» of P. Shelest. This process was particularly obvious in very concrete though discrepant steps done by the official towards Ukrainian national interests and rights protection. Among the priorities were the basics of the Ukrainian identity, such as the language, education and culture. As a devoted communist, a supporter of the Soviet Union’s «brotherhood» and a determined bearer of the communist ideas and ideals (especially in the struggle against dissidence, the Ukrainian leader, at the same time, opposed as he could the Kremlin dictatorship in particular segments of humanitarian and economical policy. It partly prevented extensive implementation of the Russian language, which had a tendency to substitute Ukrainian (the process of Russification, as well as resisted to total destruction of the Ukrainian national landscape uniqueness for the sake of Moscow’s political and ideological pressure. Simultaneously we stress, that existing myths about «autonomy», «national communism» or the program of the so called «second Ukrainisation» of P. Shelest are not proved by documents, which means these facts do not correspond to the real state of events at the mentioned historical period.

  12. VizieR Online Data Catalog: UY UMa and EF Boo compiled time of minima (Yu+, 2017)

    Science.gov (United States)

    Yu, Y.-X.; Zhang, X.-D.; Hu, K.; Xiang, F.-Y.

    2017-11-01

    In order to construct the (O-C) diagram to analyze the period change of UY UMa, we have performed a careful search for all available times of light minima. A total of 76 times of light minima were collected and listed in Table 2. >From the literatures and two well-known databases (i.e., the O-C gateway (http://var.astro.cz/ocgate) and the Lichtenknecker database of the BAV (http://www.bav-astro.de/LkDB/index.php)), we have collected a total of 75 available times of light minima for EF Boo, which are summarized in Table 3. (3 data files).

  13. The Pulkovo Observatory in the last 50 years through the eyes of its Learned Secretary Yu. I. Vitinsky.

    Science.gov (United States)

    Zhukov, V. Yu.; Soboleva, T. V.

    A solar physicist, a Pulkovo astronomer, Yury Ivanovich Vitinsky (1926-2003) was the author of 210 scientific papers known in both Russia and abroad. He worked in the Observatory for about half a century (1953-2002) and held the office of the Learned Secretary of the Russian Academy of Sciences Main Astronomical Observatory for 35 years (1965-2000). In the last years of his life, Vitinsky brought his recollections that he titled "My Pulkovo" to the Main Astronomical Observatory Archive. His memoirs narrate about problems of the astronomical science, staff members and deeds of Pulkovo, things he thought of an events he was through. This is the half-a-century history of the Pulkovo Observatory in biographies of persons. The writer of the Recollections mentions the names of fifty persons most of whom are the Main Astronomical Observatory staff members that he worked with side by side. The memoirs provide accurate descriptions that are brief yet rather capacious of the author's Pulkovo colleagues, as well as other astronomers. The language of Vitinsky's recollection is good and clear. His memoirs contain moderate balanced views of people and events and provide objective and trustworthy data. "My Pulkovo" is an indispensable biographical source for the historian of the astronomical science, the Pulkovo Observatory and its scholarly staff members of the most recent decades. It is also just an interesting human document. In 2006, Yury Ivanovich would have been eighty.

  14. Crude oil pricing in Asia and future problems; Asia no gen`yu pricing to kongo no kadai

    Energy Technology Data Exchange (ETDEWEB)

    Kato, T. [The Institute of Energy Economics, Tokyo (Japan)

    1997-01-30

    This paper describes pricing factors of crude oil for Asia and future problems. Price of the Middle East crude oil for Asia is determined by linking the spot price of Dubayy crude oil using as a marker. Factors affecting the pricing of marker crude oil include the information dispatching functions for prices of spot market and paper market of marker crude oil, the presence of competitive crude oil, and the correlation between market of oil products and price of crude oil. The paper market of Dubayy crude oil with a small scale of trading provides poor impact and transparency. In Asia, there is no strong competitive crude oil except the Middle East crude oil. There is only a weak price linking between crude oil and products. These are the background that the price of Middle East crude oil stays at the high level and the price adjusting functions are hard to work. The marker crude oil should be changed to another except Dubayy crude oil, and information should be dispatched from purchasers based on the stable standard crude oil. The real paper market should be created, and the force of speaking to oil producing countries should be enhanced by concentrating forces of major oil consuming countries in Asia. It is necessary to find out competitive crude oils. 5 figs., 6 tabs.

  15. Development of fuel economy 5W-20 gasoline engine oil; Teinenpi 5W-20 gasoline engine yu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Akiyama, K; Ueda, F; Kurono, K; Kawai, H; Sugiyama, S [Toyota Motor Corp., Aichi (Japan)

    1997-10-01

    A 5W-20 gasoline engine oil which improves vehicle fuel efficiency by more than 1.5% relative to a conventional 5W-30 gasoline engine oil was newly developed. Its high fuel economy performance lasts 10,000 km. The viscosity was optimized to satisfy both fuel economy and antiwear performances. Thiadiazole was used to retain the initial fuel economy performance provided by MoDTC. 5 refs., 7 figs., 2 tabs.

  16. Liposome-based polymer complex as a novel adjuvant: enhancement of specific antibody production and isotype switch

    Directory of Open Access Journals (Sweden)

    Chen CH

    2012-02-01

    Full Text Available Chia-Hung Chen1,*, Yu-Ling Lin1,*, Yen-Ku Liu1, Pei-Juin He2, Ching-Min Lin1, Yi-Han Chiu2, Chang-Jer Wu3, Tian-Lu Cheng4, Shih-Jen Liu5,6,**, Kuang-Wen Liao1,2,**1Institute of Molecular Medicine and Bioengineering, 2Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, 3Department of Food Science, National Taiwan Ocean University, Keelung, 4Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, 5National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, 6Graduate Institute of Immunology, China Medical University, Taichung, Taiwan, , *Chia-Hung Chen and Yu-Ling Lin contributed equally to this work**Kuang-Wen Liao and Shih-Jen Liu contributed equally to this workAbstract: The aim of vaccination is to induce appropriate immunity against pathogens. Antibody-mediated immunity is critical for protection against many virus diseases, although it is becoming more evident that coordinated, multifunctional immune responses lead to the most effective defense. Specific antibody (Ab isotypes are more efficient at protecting against pathogen invasion in different locations in the body. For example, compared to other Ab isotypes, immunoglobulin (Ig A provides more protection at mucosal areas. In this study, we developed a cationic lipopolymer (liposome-polyethylene glycol-polyethyleneimine complex [LPPC] adjuvant that strongly adsorbs antigens or immunomodulators onto its surface to enhance or switch immune responses. The results demonstrate that LPPC enhances uptake ability, surface marker expression, proinflammatory cytokine release, and antigen presentation in mouse phagocytes. In contrast to Freund's adjuvant, LPPC preferentially activates Th1-immunity against antigens in vivo. With lipopolysaccharides or CpG oligodeoxynucleotides, LPPC dramatically enhances the IgA or IgG2A proportion of total Ig, even in hosts that have developed

  17. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. SHIH-HENG TUNG. Articles written in Sadhana. Volume 33 Issue 6 December 2008 pp 767-779. Development of digital image correlation method to analyse crack variations of masonry wall · Shih-Heng Tung Ming-Hsiang Shih Wen-Pei Sung · More Details Abstract Fulltext PDF. The detection of ...

  18. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. MING-HSIANG SHIH. Articles written in Sadhana. Volume 33 Issue 6 December 2008 pp 767-779. Development of digital image correlation method to analyse crack variations of masonry wall · Shih-Heng Tung Ming-Hsiang Shih Wen-Pei Sung · More Details Abstract Fulltext PDF. The detection ...

  19. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Ming-Hsiang Shih. Articles written in Sadhana. Volume 33 Issue 6 December 2008 pp 767-779. Development of digital image correlation method to analyse crack variations of masonry wall · Shih-Heng Tung Ming-Hsiang Shih Wen-Pei Sung · More Details Abstract Fulltext PDF. The detection of ...

  20. Traditional Chinese medicine for stable angina pectoris via TCM pattern differentiation and TCM mechanism: study protocol of a randomized controlled trial.

    Science.gov (United States)

    Zhang, Zhe; Zhang, Fan; Wang, Yang; Du, Yi; Zhang, Huiyong; Kong, Dezhao; Liu, Yue; Yang, Guanlin

    2014-10-30

    Stable angina pectoris is experienced as trans-sternal or retro-sternal pressure or pain that may radiate to the left arm, neck or back. Although available evidence relating to its effectiveness and mechanism are weak, traditional Chinese medicine is used as an alternative therapy for stable angina pectoris. We report a protocol of a randomized controlled trial using traditional Chinese medicine to investigate the effectiveness, mechanism and safety for patients with stable angina pectoris. This is a north-east Chinese, multi-center, multi-blinded, placebo-controlled and superiority randomized trail. A total of 240 patients with stable angina pectoris will be randomly assigned to three groups: two treatment groups and a control group. The treatment groups will receive Chinese herbal medicine consisting of Yi-Qi-Jian-Pi and Qu-Tan-Hua-Zhuo granule and Yi-Qi-Jian-Pi and Qu-Tan-Hua-Yu granule, respectively, and conventional medicine. The control group will receive placebo medicine in addition to conventional medicine. All 3 groups will undergo a 12-week treatment and 2-week follow-up. Four visits in sum will be scheduled for each subject: 1 visit each in week 0, week 4, week 12 and week 14. The primary outcomes include: the frequency of angina pectoris attack; the dosage of nitroglycerin; body limited dimension of Seattle Angina Questionnaire. The secondary outcomes include: except for the body limited dimension of SAQ, traditional Chinese medicine pattern questionnaire and so on. Therapeutic mechanism outcomes, safety outcomes and endpoint outcomes will be also assessed. The primary aim of this trial is to develop a standard protocol to utilize high-quality EBM evidence for assessing the effectiveness and safety of SAP via TCM pattern differentiation as well as exploring the efficacy mechanism and regulation with the molecular biology and systems biology. ChiCTR-TRC-13003608, registered 18 June 2013.

  1. New Paleomagnetic Data from Upper Permian and Lower Triassic Volcanic Sequences from Hua Binh, Quynh Nhai, and Thuan Chau Localities, Northwest Veitnam and Their Bearing on the Accretion History of Southeast Asia

    Science.gov (United States)

    Geissman, J. W.; Chi, C. T.

    2015-12-01

    New paleomagnetic data from Upper Permian to Lower Triassic volcanic rocks sampled in NW Vietnam provide more quantitative constraints on the paleogeographic setting of crustal elements that comprise the Song Da Terrane, east of the Song Ma suture, between the South China block (SCB) and north Indochina. These include results from 12 sites (125 samples) from basalts of the Vien Nam Formation, exposed at Hoa Binh Dam; eight sites (74 samples) from basalts of the Cam Thuy Formation near Thuan Chau; and 19 sites (198 samples) from andesites and basalts of the Vien Nam Formation near Quynh Nhai. The collection is limited by the quality of exposures and quantity of independent flows. Most sites yield interpretable magnetizations in progressive demagnetization, and the response implies that characteristic remanent magnetization (ChRM) components are carried by low-titanium magnetite or hematite, or a combination of both; these are isolated from secondary components. Rock magnetic data and petrography support the retention of an early-acquired thermoremanent magnetization in most sites. The Vien Nam Formation mafic volcanic rocks yield a grand mean, in geographic coordinates, of D=33.8o, I=-28.4o ( a95 = 9.5o, k =30.3, N=9 accepted sites), and a pole position at Lat=41.1N, Long=239.8E and a paleolatitude at ~15o S during the Late Permian to Early Triassic. Permian basalts of the Cam Thuy Formation provide a grand mean, corrected for structural tilt, of D=216.1o, I=+10.5o, a95=8.9o, k=107.8, and N= 4, with a pole position at Lat=45.6N, Long=226.8E. Volcanic rocks at the Quynh Nhai locality likely yield the most robust paleofield determination, as the data set is of dual polarity and passes a reversal test. The tilt corrected grand mean (normal polarity) is D=48.3o, I=-10.0o, a95=8.0o, k=27.7, N = 13, and this in turn yields an inferred paleomagnetic pole at Lat=35.7N, Long=217.4E, and a paleolatitude of 5.1oS for the late Permian. Compared with the Late Permian-Early Triassic SCB apparent polar wander path, the data show that volcanic crustal elements of northwest Vietnam, east of the Song Ma suture zone, have been close to, but not unequivocally a coherent part of the SCB, since the Late Permian. Development of the parallel NW-SE striking Song Ma and Song Chay orogenic belts did not involve the closure of wide (> 500 km) ocean basins.

  2. Cetuximab-conjugated iron oxide nanoparticles for cancer imaging and therapy

    Directory of Open Access Journals (Sweden)

    Tseng SH

    2015-05-01

    Full Text Available Shih-Heng Tseng,1,2 Min-Yuan Chou,2 I-Ming Chu1 1Department of Chemical Engineering, National Tsing Hua University, 2Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan Abstract: We have developed a theranostic nanoparticle, ie, cet-PEG-dexSPIONs, by conjugation of the anti-epidermal growth factor receptor (EGFR monoclonal antibody, cetuximab, to dextran-coated superparamagnetic iron oxide nanoparticles (SPIONs via periodate oxidation. Approximately 31 antibody molecules were conjugated to each nanoparticle. Cet-PEG-dexSPIONs specifically bind to EGFR-expressing tumor cells and enhance image contrast on magnetic resonance imaging. Cet-PEG-dexSPION-treated A431 cells showed significant inhibition of epidermal growth factor-induced EGFR phosphorylation and enhancement of EGFR internalization and degradation. In addition, a significant increase in apoptosis was detected in EGFR-overexpressing cell lines, A431 and 32D/EGFR, after 24 hours of incubation at 37°C with cet-PEG-dexSPIONs compared with cetuximab alone. The antibody-dependent cell-mediated cytotoxicity of cetuximab was observed in cet-PEG-dexSPIONs. The results demonstrated that cet-PEG-dexSPIONs retained the therapeutic effect of cetuximab in addition to having the ability to target and image EGFR-expressing tumors. Cet-PEG-dexSPIONs represent a promising targeted magnetic probe for early detection and treatment of EGFR-expressing tumor cells. Keywords: epidermal growth factor receptor, cetuximab, superparamagnetic iron oxide nanoparticle, magnetic resonance imaging, sodium periodate, polyethylene glycol

  3. FITTER. The package for fitting experimental data of the YuMO spectrometer by theoretical form factors. Version 1.0. Long write-up and user's guide

    International Nuclear Information System (INIS)

    Solov'ev, A.G.; Stadnik, A.V.; Islamov, A.Kh.; Kuklin, A.I.

    2003-01-01

    FITTER is a C++ code aimed to fit a chosen theoretical multi-parameter function through a set of data points. The method of fitting is chi-square minimization. Moreover, the robust fitting method can be applied. FITTER was designed for a small-angle neutron scattering data analysis, using respective theoretical models. Commonly used models (Gaussian and polynomials) are also implemented for wider applicability

  4. Can yu rid guat ay rot? A Developmental Investigation of Cross-Linguistic Spelling Errors among Spanish-English Bilingual Students

    Science.gov (United States)

    Howard, Elizabeth R.; Green, Jennifer D.; Arteagoitia, Igone

    2012-01-01

    This study contributes to the literature on cross-linguistic literacy relationships for English language learners, and in particular, the Spanish-influenced spelling patterns of Spanish-English bilinguals. English spelling, reading, and vocabulary assessments were administered to 220 students in four TWI programs over a three-year period, from…

  5. TattooYU: Tattooed Souvenirs from the Yugoslav People’s Army and Regimes of Memory of the Body Inscribed with Socialism

    Directory of Open Access Journals (Sweden)

    Sandi Abram

    2015-08-01

    Full Text Available The paper focuses on the first mass imprints on the body in the entire region of the former Yugoslavia, which eternally marked members of its armed forces. Through bodies permanently imprinted with socialist history and narrations of tattooed solders from the Yugoslav People’s Army (YPA, I install tattoos from YPA in-between the subversion of power and the incorporation of the dominant ideology, in the antithesis between uniformity and subjectivity. Above all, tattoos from YPA function as a mnemotechnical practice of recollection of the cultural memory, which awakens narrations and the regimes of memory as well as the regimes of memorization of the YPA, socialism and the period of (post transition. Whereas the collected ethnographical material will sustain the claims made above, the situations in which the ethnography was impossible will be discussed further. Rejection, reflex silence or refusals of collaboration are all peculiar modes through which the paper emphasises the importance of the “ethnography of absent” (Telban. In this vein, they represent a fertile springboard to discuss notions of productive oblivion (Kuljić, forgetting (Ricoeur and the “eloquent reticence”. The recollection of negative sentiments (as a way of activating the past did not only materialize in tattooees’ non-responses. Tattoos from YPA also triggered practices of extreme permanent tattoo concealment (e.g. cicatrisation, cauterization that do not fit into the classical anthropological milieu as practices of embellishment, rites of passage, strengthening the pain-tolerance threshold, etc. Instead, I see these practices as a preliminary phase of oblivion and as ways of “deideologization”. Furthermore, the paper supplements Connerton's “habitual memory” preserved in the body and conserving the past in the memory, with its material constitutional side on the body – the tattoo.

  6. The Analysis of Differences and Similarities of Eastern and Western Women’s Images in Liang Sanbo Yu Zhu Yingtai and Romeo and Juliet Novel

    Directory of Open Access Journals (Sweden)

    Yenny Yenny

    2010-11-01

    Full Text Available Sanpek Engtay and Romeo Juliet are the two famous classic love novels from Eastern and Western countries. They are liked by many generation of eastern and western readers. Both novels describe the image of women at each decade. Engtay represents the image of women at feudalism era while Juliet represents it Renainsance era. In this article, the writer did research at education, marriage, love, women's personality, and women's position at each decade. Library research was done in this study with the purpose of letting people know the differences and similarities of women's images between those two decades It can be concluded that in both writings, they have some similarities when describing love, mindset, and women's personality. The differences are about education, marriage, and women's position at feudalism and Renainsance decades.

  7. Problems concerning abolishment of the ban on exportation of Alaskan crudeoil. Alaska gen'yu no yushutsu kaikin mondai no yukue

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    The ban on exhortation of Alaska North Slope (ANS) crude oil is being vigorously discussed on its maintenance or abolishment. The Department of Energy of the U.S. published the report which emphasized merits by abolishing the ban on ANS crude-oil exporting. The American Crew Union asserts that the Union will agree to the abolishment if ANS crude oil is transported by the Johns Act ships, which mean tankers built in the U.S., having the U.S. nationality, and plied by operation of the U.S. crews. The federal government of the U.S. declares that the government will not support the abolishment unless the items to restrict the transportation within Johns Act ships are deleted. It is said that British Petroleum, the largest producer of ANS crude oil, is sounding for the method in which use of the U.S. ships and employment of the U.S. crews for the transportation are guaranteed by direct contracts with the tanker owners and crews of the U.S. In any case, employment of U.S. crews is considered to the point to realize the abolishment of the bat on exportation of ANS crude oil.

  8. Radiation defect production in quartz crystals with various structure perfectness degree; Radiatsionnoe defektoobrazovanie v kristallakh kvartsa s razlichnoj stepen`yu sovershenstva struktury

    Energy Technology Data Exchange (ETDEWEB)

    Khushvakov, O B

    1992-01-01

    Radiation defects production processes in pure and doped quartz crystals with various structure defectness, caused by preliminary irradiation with neutrons, protons, deuterons and {alpha}-particles, during various electron excitation densities were investigated. The distribution of colour centres along the thickness of irradiated quartz crystals was measured. It was supposed that colour centres are produced on account of inelastic energy losses as the result of collective decay of two or more interacting excitons. It was shown that in quartz crystals under the actions of protons with overthreshold energy 18 MeV and electrons with subthreshold energy 100 keV the same structure defects are formed. It was established that radiation defect production process has two stages. The first stage reveals radiation defects produced by preliminary irradiation. The second one reveals additional intrinsic defects formed under the action of gamma-rays and electrons. The probability dependence of defect production on neutron fluence and masses of incident particles was studied. It was supposed that the creation of additional defects in preliminary irradiated crystals is due to non-radiative decay of electron excitations near radiation-induced defects. It was shown that increase of impurity concentration leads to rate growth of accumulation of radiation induced defects. (A.A.D.) 15 refs. 4 figs.

  9. Radiation Disinfestation of Grain and Seeds; Radiodesinsection des Cereales et des Semences; Obezzarazhivanie zerna i semyan s pomoshch'yu oblucheniya; Desinfestacion de Granos y Semillas por Irradiacion

    Energy Technology Data Exchange (ETDEWEB)

    Golumbic, C.; Davis, D. F. [Market Quality Research Division, Agricultural Research Service, United States Department of Agriculture, Hyattsville, MD (United States)

    1966-11-15

    Current interest in radiation treatment of grain and seeds mainly revolves about its efficacy for control of insect infestations in these products. The recent literature on this subject is reviewed and gaps still existing in the fundamental and practical knowledge of radiation disinfestation.are pointed out. Research programmes in the United States Department of Agriculture that are under way, or planned for the immediate future, are discussed in detail. Current studies are being directed toward establishing minimum effective doses for sexual sterilization and mortality, influence of environmental factors on dose requirements, and potential for the development of biological resistance. In May 1966 the scope of the work expanded as a new grain products irradiator became operative and applied studies were initiated. An integral part of this, research is a study of the effect of irradiation on the quality of food and feed grains and on cereal products, at the doses for both insect control and fungal disinfection. This paper examines critically the results of research in this area and estimates future research, needs. (author) [French] A'.l'heure actuelle, l'interet que suscite le traitement par les rayonnements des cereales et des semences est du avant tout a son efficacite pour la desinsection. Les auteurs analysent les recentes publications dans ce domaine et. signalent les lacunes, qui subsistent encore dans les connaissances fondamentales ou pratiques relatives a la radiodesinsection, ' Ils examinent en detail les programmes de recherches du Departement de l'agriculture des Etats-Unis qui sont actuellement mis.en oeuvre ou projetes pour l'avenir immediat. Les etudes actuelles concernent la determination de la dose minimale necessaire pour la sterilisation sexuelle et de la dose mortelle, l'influence des facteurs ambiants sur les doses requises, et les possibilites de developpement de la resistance biologique. En mai 1966, les travaux se sont elargis a la suite de la mise en service d'une nouvelle installation d'irradiation des.cereales qui permet d'entreprendre des etudes appliquees. Ce programme comprend l'etude des effets de l'irradiation aux doses insecticides et fongicides sur la qualite des cereales destinees a la consommation humaine et animale et sur celle des produits derives. Le memoire procede a un examen critique des resultats des recherches entreprises et evalue les besoins, futurs a cet egard. (author) [Spanish] El interes que suscita el tratamiento de granos y semillas por irradiacion radica principalmente en su eficacia en la lucha contra la infestacion de esos productos por insectos. Los autores examinan las publicaciones mas recientes sobre esta cuestion y senalan las lagunas que todavia existen en los conocimientos basicos y practicos de la radiodesinfestacion. Exponen detenidamente los programas de investigacion del Departamento de Agricultura de los Estados Unidos que se estan ejecutando o que se proyecta ejecutar en un futuro inmediato. Los estudios actuales estan orientados hacia el establecimiento de valores minimos de dosis eficaces para la esterilizacion sexual y para provocar la muerte de los insectos, la influencia de los factores ambientales sobre las dosis necesarias y las posibilidades de desarrollo de una resistencia biologica. En mayo de 1966 se amplio el alcance de estos trabajos con la entrada en servicio de una nueva instalacion de cereales y derivados y se iniciaron estudios de aplicacion. Como parte integrante de esas investigaciones se lleva a cabo un estudio de los efectos de la irradiacion sobre la calidad del grano destinado a la alimentacion humana o utilizado como pienso, y sobre los productos derivados de los cereales. Esa irradiacion se efectua con las dosis que se precisan en la lucha contra los insectos y con las empleadas para la eliminacion de hongos. Los autores hacen un estudio critico de los resultados de las investigaciones que se realizan en este sector y evaluan las futuras necesidades en materia de investigacion. (author) [Russian] V nastojashhee vremja obrabotka zerna i semjan s pomoshh'ju obluchenija predstavljaet interes glavnym obrazom s tochki zrenija opredelenija ee jeffektivnosti v dele obespechenija kontrolja za zarazheniem jetih produktov parazitami. Rassmatrivaetsja sovremennaja literatura po jetomu voprosu i ukazyvajutsja vse eshhe sushhestvujushhie problemy v oblasti fundamental'nyh i prakticheskih znanij o sposobah obezzarazhivanija s pomoshh'ju obluchenija. Podrobno rassmatrivajutsja nauchno-issledovatel'skie programmy ministerstva sel'skogo'hozjajstva SShA, kotorye nahodjatsja v stadii vypolnenija ili planirujutsja na blizhajshee budushhee. Provodimye v nastojashhee vremja issledovanija napravleny na ustanovlenie minimal'nyh jeffektivnyh doz dlja polovoj sterilizacii i smertnosti, vlijanija okruzhajushhih faktorov na dozovye potrebnosti i vozmozhnosti dlja razvitija biologicheskoj soprotivljaemosti. V mae 1966 goda ob{sup e}m rabot budet rasshiren, tak kak budet vvedena v jekspluataciju novaja ustanovka po oblucheniju zernovyh produktov i nachnutsja prikladnye issledovanija. Sostavnoj chast'ju jetih nauchno-issledovatel'skih rabot javljaetsja izuchenie vlijanija obluchenija na kachestvo pishhi i furazha, a takzhe produktov iz hlebnyh zlakov pri dozah, obespechivajushhih kontrol' za parazitami i unichtozhenie gribkov. V dannom doklade kriticheski rassmatrivajutsja rezul'taty nauchno-issledovatel'skoj raboty v jetoj oblasti i opredeljajutsja potrebnosti v nauchnyh issledovanijah v budushhem. (author)

  10. The radiation age of meteorites; L'age des meteorites; Opredelenie vozrasta meteoritov s pomoshch'yu radiatsii; Edad de los meteoritos

    Energy Technology Data Exchange (ETDEWEB)

    Goebel, K; Schmidlin, P [European Organisation for Nuclear Research, Geneva (Switzerland)

    1962-01-15

    Radioisotopes produced by cosmic radiation in meteorites while travelling through space can be used to trace the history of these meteorites. The radioisotopes and the accumulated daughter-elements in the meteorite must be determined in order to evaluate how long the meteorite was exposed to cosmic radiation. (It must be assumed for this calculation that the flux of the cosmic radiation is constant with time.) Most often gaseous isotopes have been used for these measurements as they can be easily separated from the meteoric substance. In the reported work tritium and argon have been mainly used. From the ratio H{sup 3}/He{sup 3}, radiation ages from a few millions to several hundred millions of years have been found. The recent measurements made at the European Organisation for Nuclear Research (CERN) agree in principle with results from other sources. The probable errors from diffusion-losses of gas and the influence of shielding in the pre-atmospheric meteorite are discussed in the paper. By taking into consideration the measured cross-section for tritium production in the elements which form the meteorite, the values of the cosmic-ray flux in outer space can be determined. (author) [French] Les radioisotopes produits par les rayonnements cosmiques dans les meteorites circulant dans l'espace peuvent servir a reconstituer l'histoire de ces corps. Il faut mesurer les radioisotopes et les produits de filiation accumules dans la meteorite pour evaluer le temps pendant lequel la meteorite a ete exposee aux rayonnements cosmiques. (On considere alors que le flux des rayonnements cosmiques ne varie pas dans le temps.) Pour ces mesures, on se fonde le plus souvent sur les isotopes gazeux parce qu'il est facile de les separer de la substance meteorique. Dans les recherches qui font l'objet du present memoire, il s'agissait surtout du tritium et de l'argon. En partant du rapport {sup 3}H/{sup 3}He, on a pu evaluer des ages allant de quelques millions a plusieurs centaines de millions d'armees. Les mesures recemment effectuees au C E R N concordent en principe avec les resultats auxquels ont abouti d'autres auteurs. Le memoire traite des erreurs probables qui peuvent resulter des pertes de gaz par diffusion, et de la protection dont la meteorite beneficie dans la preatmosphere. E n tenant compte de la section efficace pour la production de tritium dans les elements qui constituent la meteorite, on peut determiner les valeurs du flux des rayons cosmiques dans l'espace extra-atmospherique. (author) [Spanish] Los radioisotopos formados por la accion de los rayos cosmicos sobre los meteoritos durante el recorrido de estos a traves del espacio pueden utilizarse para reconstruir el historial de estos cuerpos. Para evaluar el tiempo durante el cual el meteorito estuvo expuesto a los rayos cosmicos, es preciso determinar cuantitativamente los radioisotopos y los elementos descendientes que se han acumulado en el mismo. (A fin de poder efectuar el calculo, hay que suponer que el flujo de rayos cosmicos ha permanecido constante en el tiempo.) Estas mediciones se basan con frecuencia en los isotopos gaseosos, y a que estos pueden separase con facilidad del resto de la materia meteoritica. E n los trabajos objeto de este informe, se han empleado principalmente el tritio y el argon. A partir de la razon {sup 3}H/{sup 3}He se han podido calcular edades que abarcan de algunos millones a varios cientos do millones de anos. Las mediciones recientemente efectuadas en el CERN concuerdan esencialmente con los resultados obtenidos por otros investigadores. Los autores discutiran los errores probables debidos a las perdidas de gases por difusion, asi como el efecto de blindaje del meteorito en su recorrido preatmosferico. Si se tienen en cuenta los valores medidos de la seccion eficaz para la produccion de tritio a partir de los elementos de que se compone el meteorito, es posible determinar el flujo de rayos cosmicos en el espacio sideral. (author) [Russian] Radioizotopy, voznikayushchie v rezul'tate kosmicheskoj radiatsii v meteoritakh vo vremya ikh dvizheniya v kosmose, mogut byt' ispol'zovany dlya togo, chtoby prosledit' istoriyu ehtikh tel. Radioizotopy i akkumulirovannye dochernie ehlementy v meteorite dolzhny byt' opredeleny dlya vyrazheniya vremeni, v techenie kotorogo meteorit podvergalsya kosmicheskoj radiatsii. (Dlya vychisleniya neobkhodimo dopustit', chto potok radiatsii yavlyaetsya postoyannym v techenie vsego vremeni). Dlya izmereniya obyknovenno ispol'zuyutsya izotopy gazov, poskol'ku oni mogut byt' legko otdeleny ot samogo meteorita. V dannom issledovanii ispol'zovany, glavnym obrazom, tritij i argon. Po koehffitsientu radiatsii H3{sup /}He{sup 3} opredelyalsya vozrast meteorita ot neskol'kikh millionov let do neskol'kikh soten let. Poslednie izmereniya v TSERNe v printsipe soglasuyutsya s rezul'tatami drugikh issledovanij. V rabote obsuzhdayutsya voprosy vozmozhnykh otklonenij vvidu diffuzionnykh poter' gaza i vliyaniya ehkranirovki v atmosfernom meteorite. Velichina potoka kosmicheskikh luchej vo vneshnem prostranstve mozhet byt' opredelena, esli prinyat' vo vnimanie zamerennoe poperechnoe sechenie produktov tritiya v ehlementakh, kotorye obrazuyut meteorit. (author)

  11. Noel Maurer and Carlos Yu.  The Big Ditch:  How America Took, Built, Ran, and Ultimately Gave Away the Panama Canal

    Directory of Open Access Journals (Sweden)

    Joseph Michael Gratale

    2011-03-01

    Full Text Available In 1959, William Appleman Williams published The Tragedy of American Diplomacy.  It was a book that boldly set out to trace the contours of America’s imperial trajectory from the late nineteenth century to the middle of the twentieth century.  Williams’ approach to U.S. foreign policy put him in the vanguard of what would become New Left historical revisionism during the 1960s.  His reassessment of American history which in part involved his deployment of such concepts as imperialism and empi...

  12. Correction: Yu, Q., et al. Narrowband Bio-Indicator Monitoring of Temperate Forest Carbon Fluxes in Northeastern China. Remote Sens. 2014, 6, 8986-9013

    Directory of Open Access Journals (Sweden)

    Remote Sensing Editorial Office

    2015-01-01

    Full Text Available Due to a technical error at the Editorial Office, Figure 8 of manuscript [1] is missing in the published paper. The correct version of the figure is reproduced below. We apologize for any inconvenience caused to authors or readers of Remote Sensing.[...

  13. CHARACTERISTICS OF MEI-YU PRECIPITATION AND SVD ANALYSIS OF PRECIPITATION OVER THE YANGTZE-HUAIHE RIVERS VALLEYS AND THE SEA SURFACE TEMPERATURE IN THE NORTHERN PACIFIC OCEAN

    Institute of Scientific and Technical Information of China (English)

    MAO Wen-shu; WANG Qian-qian; PENG Jun; LI Yong-hua

    2008-01-01

    Based on the precipitation data of Meiyu at 37 stations in the valleys of Yangtze and Huaihe Rivers from 1954 to 2001, the temporal-spatial characteristics of Meiyu precipitation and their relationships with the sea surface temperature in northern Pacific are investigated using such methods as harmonic analysis, empirical orthogonal function (EOF), composite analysis and singular value decomposition (SVD). The results show that the temporal evolution and spatial distribution of Meiyu precipitation are not homogeneous in the Yangtze-Huaihe Rivers basins but with prominent inter-annual and inter-decadal variabilities. The key region between the anomalies of Meiyu precipitation and the monthly sea surface temperature anomalies (SSTA) lies in the west wind drift of North Pacific, which influences the precipitation anomaly of Meiyu precipitation over a key period of time from January to March in the same year. When the SST in the North Pacific west wind drift is warmer (colder) than average during these months, Meiyu precipitation anomalously increases (decreases) in the concurrent year. Results of SVD are consistent with those of composite analysis which pass the significance test of Monte-Carlo at 0.05.

  14. 平生足悲吒----論韓愈詩的憂憤悲懷/The Sadness of Life-Han Yu's Poetry of Grief and Sorrow

    Directory of Open Access Journals (Sweden)

    Ming-chang LIN

    2012-09-01

    This paper is a study of the element of melancholy apprehension in Han Yu’s poetry. Han’s apprehension of melancholy, which up to now has received very little attention, is discussed in three aspects: (1 the fear of old age and sickness, (2 the fear of hunger and cold, and (3 the fear of death. Against the background of Han Yu’s unstable and uncertain life and career, the new reading and analysis show that melancholy lies at the very heart of his personality and writing.

  15. PRIVERZhENNOST' PROFILAKTIKE OSTEOPOROZA I VLIYaYuShchIE NA NEE FAKTORY U ZhITEL'NITs MOSKOVSKOY OBLASTI

    Directory of Open Access Journals (Sweden)

    L A MARChENKOVA

    2014-12-01

    Full Text Available Despite high prevalence and severity of complications, osteoporosis (OP in Russia is still not recognized as a socially significant disease and there are no common standards for prevention of OP and associated fractures. The aim of the study was to investigate the adherence of healthy females to prevention measures of OP and the affecting it factors to develop the principles governing the preventive strategy of OP. Methods. The study is performed in Moscow Region (MR in a form of a questionnaire survey in the population of adult healthy women aged >20 years. The data are obtained using "Questionnaires on osteoporosis prevention" and "The test of knowledge in the field of osteoporosis" developed in Clinical Research Institution of Moscow Region named after M.F. Vladimirsky. Study comprised 1712 female aged from 20 till 87 years (median 55,0 years [45,0; 44,0] living in 16 districts and 11 cities of MR. Taking into account the quality of the filling of questionnaires, data provided by 1631 women were included in the statistical analysis. Results. It is established that 31% of female inhabitants of MR are engaged in OP prevention, using for this purpose mainly calcium-containing drugs (64,3% and increased consumption of calcium in food (59,8%. 93% of these women get preventive therapy at their own expense, spending on them on the average 200 rub a month, and preventive medication has appeared more saving than non-pharmacological preventive measures. Socially active working women at the age of 50-69 years are motivated on prevention of OP better than others. Level of the OP awareness and undertaking densitometry screening also directly influence adherence to OP prevention.

  16. Battling coal and rock dust in mines. Bor'ba s ugol'noi i porodnoi pyl'yu v shakhtakh

    Energy Technology Data Exchange (ETDEWEB)

    Petrukhin, P.M.; Grodel, G.S.; Korenev, A.P.; Krivokhizha, B.M.; Kul' bachnyi, A.N.; Lyubimova, A.I.; Medvedev, E.N.; Yaremachenko, P.P.; Zhilyaev, N.I.

    1981-01-01

    The problems of comprehensive removal of dust from the atmosphere in mines are discussed. Physical and pnysicochemical properties of mine dust are described, which are important for estimating the processes of its formation, spread, and suppression. Presented are the results of theoretical and natural studies of dust aerodynamics of mines. Modern methods for battling coal and rock dust in mines, as well as means of monitoring the dust level of the air are outlined. Technical descriptions are given for new instruments for changing the dust level of the air. Brief reports are given on the preliminary wetting of coal in the massif, and theoretical and practical problems are discussed concerning hydrological methods of dust removal, dust suppression by foam, and dust trapping during the operation of mining equipment, and also on removal of dust from the air at the surface complex of a mine.

  17. Control of coal-dust in mines. Second edition. Bor'ba s ugol'noi i porodnoi pyl'yu v shakhtakh

    Energy Technology Data Exchange (ETDEWEB)

    Pemrukhin, P.M.; Grodel, G.S.; Zhilyaev, N.I.; Korenev, A.P.; Krivokhizha, B.M.; Kul' bachnyi, A.N.; Lyubimoba, A.I.; Medvedev, E.N.; Yaremachenko, P.P.

    1981-01-01

    An examination is made of problems concerned with over-all removal of dust from the air in mines. A description is given of physical and physico-chemical properties of ore mine dust that are of importance to evaluating processes in the formation, propagation and suppression of dust. Results are given for theoretical and on-site studies of dust aerodynamics in mines. A presentation is made of contemporary measures for controlling coal and rock dust in mines as well as means and methods of controlling air dust-level. Technical characteristics are given for new instruments for measuring air dust level. Brief data are given on preliminary wetting of coal in a massif, and a discussion is made of theoretical and practical problems related to hydro-dedusting, dust suppression, and dust removal during the operation of mining machinery as well as instruments for dedusting air on the surface complex of a mine. The book is intended for engineering-technical personnel in coal mines, design-planning and scientific-research institutes. 52 references, 61 tables.

  18. Opyt primeneniya ingibitora angiotenzinprevrashchayushchego fermenta spiraprila u bol'nykh gipertonicheskoy bolezn'yu v sochetanii s sakharnym diabetom 2 tipa

    Directory of Open Access Journals (Sweden)

    A F Tushova

    2008-06-01

    Full Text Available Цель. Оценка влияния иАПФ спираприла на плазменно-тромбоцитарный гемостаз, углеводный обмен и липидный профиль у больных ГБ, ассоциированной с СД 2. Материалы и методы. Под динамическим наблюдением находилось 33 больных СД 2 и ГБ (1-я ст. ? 2 (6,06%, 2-я ст. ? 9 (27,27%, 3-я ст. ? 22 (66,67% больных. Контрольную группу составили 35 больных гипертонической болезнью (1-я ст. ? 4 (11,43 %, 2-я ст. ? 14 (40 %, 3-я ст. ? 17 (48,57% без СД. Антропометрическое исследование включало измерение массы тела, объема талии (ОТ и бедер (ОБ, расчет ОТ/ОБ, индекса массы тела (ИМТ. Содержание глюкозы в крови определялось глюкозооксидазным методом в капиллярной крови натощак, через 1 и 2 часа в ходе стандартного перорального глюкозотолерантного теста с 75 г глюкозы. Исследовались липидный спект, экскреция альбумина, коагуляцинное звено гемостаза, тромбоцитарное звено гемостаза. Результаты. МАУ (экскреция альбумина >20 мг/л исходно диагностирована у 28 больных (84,85%. Через 4 недели лечения спираприлом у 93,94% больных отмечалось уменьшение уровня экскреции альбумина с мочой. У обследованных больных СД 2 с ГБ отмечены нарушения во всех звеньях гемостаза, но, в отличие от контрольной группы, были менее выражены нарушения спонтанной агрегации тромбоцитов. У больных СД с ГБ гиперкоагуляция наблюдалась преимущественно по внешнему пути свертывания крови. Заключение. У больных СД и ГБ повышен тромбогенный потенциал крови. В результате лечения спираприлом отмечена положительная динамика ? активация фибринолитической системы, снижение спонтанной агрегации тромбоцитов и нормализация в коагуляционном звене гемостаза. На фоне терапии спираприлом наблюдается улучшение показателей углеводного и липидного обмена. Спираприл обладает нефропротективным эффектом, что проявилось снижением уровня МАУ. Лечение спираприлом не влияло на динамику массы тела, ИМТ, отношения ОТ/ОБ.

  19. Study of effects of engine oil additives on the properties of fluorelastomers; Fusso gomu ni oyobosu engine yu tenkazai no eikyo chosa

    Energy Technology Data Exchange (ETDEWEB)

    Kurono, K; Owaki, M; Suzuki, Y; Akiyama, K; Shionoya, M [Toyota Motor Corp., Aichi (Japan)

    1997-10-01

    Fluoroelastmers are well known for their resistance to heat and fluids and have become major material for crankcase oil sealers. On the other hand new additive formulations are developed for engine lubricants used for fuel economic gasoline engines. In this paper the effects of those additives on properties of fluoroelastmers are investigated. The results of the immersion tests of both test plaques and oil sealer products indicates that dithiocarbamates friction modifier have hardening effects on fluoroelastomers. The fluoroelastmer deterioration mechanism is presumed by analysis of elastmer samples after immersion in oil. 6 refs., 9 figs., 3 tabs.

  20. 真實性與主體性的追求:本土主義和多元文化主義影響下的臺灣原住民儀式展演 (Zhenshixing yu zhutixing de zhuiqiu: bentu zhuyi yu duoyuan wenhua zhuyi yingxiang xia de Taiwan yuanzhumin yishi zhanyan)

    DEFF Research Database (Denmark)

    Rudolph, Michael

    2017-01-01

    展演理論的擁護者強調展演對於社會組織和權威的模式存在建設性和變革性的潛在影響。對於他們來說,「儀式不僅意味深長,且具有實際用途,尤其在建構與題寫權力關系方面」(Bell 1997)。本篇論文側重於儀式展演在台灣後殖民意識形成中的角色, 以及在政治權力和社會權威認證(authentication)中的主要作用。自從20世紀90年代中期,原住民的展演開始在島內盛行,政府為了試圖宣揚台灣的本土和多元化文化取向,紛紛慷慨資助,原住民菁英們不僅公開崇拜先祖神靈,在所謂 「復振」的公共儀式中還使用動物祭祀,並在這種場合,向過去的漢族殖民者彰顯原住民的原生力。然而,在許多情況下,這些被復振的儀式與原住...

  1. Selective Neoplasm Localization with Mercury-197 Neohydrin; Localisation Selective de Neoplasmes a l'aide de la Neohydrine Marquee avec {sup 197}hg; Obnaruzhenie opukholej s pomoshch'yu neogidrina, mechennogo rtut'yu-197; Localizacion Selectiva de Neoplasmas con Neohidrina - {sup 197}hg

    Energy Technology Data Exchange (ETDEWEB)

    Sodee, D. B. [Doctors Hospital and Renner Clinic Foundation, Cleveland Heights, OH (United States)

    1964-10-15

    Hg{sup 197} a low-energy X- and gamma- ray emitter (2.7-d half-life, 69-keV conversion X-rays, 77-keV gamma-rays) was tested as a scanning agent in a large series of patients. Five hundred patients suspected of neuro-surgical disease were scanned with Hg{sup 197}-Neohydrin. Utilizing photoscanning techniques that brought out vascular lesions as well as tumours, this procedure had a 96% correlation with the final diagnostic evaluation. This screening procedure was done before all other diagnostic tests. As an outgrowth of this brain-scanning procedure, we have found localization of Hg{sup 197}-Neohydrin in lymphomas as well as in carcinomas. There seems to be selective deposition of the radioactive substance intercellularly. Areas of increased uptake of radioactivity can easily be delineated with standard commercial scanners. Hg{sup 197}-Neohydrin was also found to be useful as a screening agent in thc differentiation of eye tumours in a series of 88 patients and recently this low-energy radiopharmaceutical was found to concentrate in naso- pharangeal tumours which could then be delineated by photoscanning. The diagnostic dose of Hg{sup 197}-Neohydrin for brain scanning delivers a radiation dose of 3 rad to the kidneys as compared to the 70 rad delivered to the kidneys by that of Hg{sup 203}-Neohydrin. The high counting efficiency and ease of collimation of Hg{sup 197} make this isotope far better for scanning purposes than all other standard diagnostic scanning agents. (author) [French] Le mercure-197, emetteur de rayons X et de rayons gamma de faible energie (periode de 65 h, rayons X de 69 keV, rayons gamma de 77 keV), a ete essaye comme agent d'exploration scintigraphique sur un grand nombre de patients. On a utilise la neohydrine marquee avec {sup 197}Hg pour la scintigraphie de 500 cas de neurochirurgie. Par des procedes de photoscintigraphie qui permettaient la visualisation des lesions vasculaires aussi bien que celle de tumeurs, on a obtenu des resultats confirmes dans 96% des cas par le diagnostic final. La scintigraphie etait toujours faite avant tous les autres tests. L'application de cette methode de scintigraphie du cerveau a permis, en outre, de constater que la neohydrine marquee avec {sup 197}Hg etait localisee aussi bien dans les lymphomes que dans les carcinomes. Il semble y avoir depot selectif de la substance radioactive au niveau intercellulaire. Les zones de fixation accrue de la radioactivite peuvent etre aisement delimitees avec des agents scintigraphiques courants. Des essais sur 88 patients on montre que la neohydrine marquee avec {sup 197}Hg etait egalement utile comme agent de detection pour differencier les tumeurs des yeux; enfin, on a constate tout recemment qu'elle se concentrait dans les tumeurs rhino-pharyngiennes, que l'on pouvait alors delimiter par photoscintigraphie. La quantite de neohydrine marquee avec {sup 197}Hg necessaire a une scintigraphie du cerveau delivre au reins une dose de 3 rad, contre 70 rad pour la neohydrine marquee avec {sup 203}Hg, Du fait de la grande efficacite de comptage et de la facilite de collimation, {sup 197}Hg convient mieux que tous les autres agents classiques de diagnostic par scintigraphie. (author) [Spanish] El autor ensayo como agente de exploracion el {sup 197}Hg, emisor de rayosX y gamma de baja energia (periodo: 2,7 d; rayos X de conversion: 69keV; rayos gamma: 77keV). Quinientos pacientes, que presentaban sintomas de afecciones neuroquirurgicas, fueron examinados mediante neohidrina-{sup 197}Hg. Aplicando tecnicas de fotoexploracion que revelan tanto las lesiones vasculares como los tumores, se comprobo que entre los resultados asi obtenidos y el diagnostico definitivo habla una correlacion del 96%. Ese procedimiento de examen se aplico antes de proceder a las demas pruebas diagnosticas Como resultado de la aplicacion de ese procedimiento de exploracion del cerebro, el autor descubrio localizaciones de neohidrina-{sup 197}Hg en linfomas y carcinomas. Al parecer, la sustancia radiactiva tiende a depositarse selectivamente en regiones intercelulares. Con los aparatos de exploracion de. tipo comercial se pueden delinear facilmente las zonas de mayor absorcion de radiactividad. Tambien se comprobo la utilidad de la neohidrina-{sup 197}Hg para la diferenciacion de tumores oculares en una serie de 88 pacientes - recientemente se ha observado que este compuesto radiofarmaceutico de baja energia se concentra en los tumores nasofaringeos que luego pueden delinearse por fotoexploracion. La dosis diagnostica de neohidrina-{sup 197}Hg administrada para la exploracion del cerebro entrafla la absorcion de 3 rad por el riflon; la de neohidrina-{sup 203}Hg entrafla la absorcion de 70 rad por este ultimo organo. El elevado rendimiento de recuento del {sup 197}Hg y la facilidad con que se coliman las radiaciones que emite, hacen que este isotopo resulte mucho mas util para la exploracion gammagra-fica que cualquier otro de los agentes habitualmente empleados. (author) [Russian] RtuT'-197-izluchatel' rentgenovskih i gamma-luchej maloj jenergii (period poluraspada 2,7 dnja, konversionnoe rentgenovskoe izluchenie moshhnost'ju 69 kjev, gamma-izluchenie 77 kjev) byl oprobovan v kachestve skennirujushego sredstva v bol'shogo kolichestva bol'nyh. U 500 bol'nyh s predpolagaemymi nervohirurgicheskimi zabolevanijami proizvedeno skennirovanie po izlucheniju neogidrina, mechennogo Hg{sup 197}. S pomoshh'ju metoda fotOskennirovanija udalos' vyjavit' porazhenie sosudov i opuholi, prichem jeta metodika v 96% obespechivala korreljaciju s okonchatel'nym diagnozom. Jeta metodika rentgenologicheskogo issledovanija predshestvovala vsem drugim vidam diagnosticheskogo obsledovanija. S pomoshh'ju metoda skennirovanija golovnogo mozga avtory obnaruzhili lokalizaciju Neogidrina-Hg{sup 197} kak v limfomah, tak i v karcinomah. Po-vidimomu, imeet mesto mezhkletochnoe selektivnoe otlozhenie radioaktivnogo veshhestva. Uchastki usilennogo pogloshhenija radioaktivnosti mozhno legko opredelit' s pomoshh'ju standartnyh imejushhihsja v prodazhe skennirujushhih ustrojstv. Neogidrin, mechennyj Hg{sup 197}, okazalsja prigodnym sredstvom dlja radiologicheskogo issledovanija pri ustanovlenii differencial'nogo diagnoza glaznyh opuholej u 88 bol'nyh. Nedavno bylo obnaruzheno, chto jetot radiofarmacevticheskij preparat s mjagkim izlucheniem koncentriruetsja v opuholjah nosoglotki, kontur kotoryh mozhno zatem opredelit' s pomoshh'ju fotoskennirovanija. Diagnosticheskaja doza neogidrina - Hg{sup 197} dlja skennirovanija golovnogo mozga sozdaet dozu obluchenija pochek, ravnuju 3 rad, v to vremja kak diagnosticheskaja doza neogidrina -Hg{sup 203} sozdaet dozu obluchenija v 70 rad. Blagodarja vysokoj jeffektivnosti scheta i legkosti kollimacii Hg{sup 197}, jetot izotop v gorazdo bol'shej stepeni otvechaet celjam skennirovanija, chem vse drugie standartnye sredstva diagnosticheskogo skennirovanija. (author)

  2. Renal Scintiscanning with Hg{sup 209}-Neohydrin in Urologic Diseases; Scintigraphy du Rein dans les Maladies des Voies Urin Aires au Moyen de Neohydrine Marquee avec {sup 203}Hg; Stsintillyatsionnoe skennirovanie pochek s pomoshch'yu neogidrina,mechennogo Rtut'yu-203, pri urologicheskikh zabolevaniyakh; Exploracion Centelleografica del Rinon con Neohydrina - {sup 203}hg en las Afecciones Urologicas

    Energy Technology Data Exchange (ETDEWEB)

    Bollini, V.; Tori, G. [Radiology Institute of the University of Bologna (Italy)

    1964-10-15

    Renal scintiscanning has been carried out using Hg{sup 203} - labelled Neohydrin. The equipment used is the Nuclear Chicago Isotope Scanner Type 1700 with 2 x 2 - i n crystal and a 7 - cm focal-length honeycomb collimator. Usually the scintigrams are registered both on paper and on photographic film. Hg{sup 203} - labelled Neohydrin is usually employed in doses of 120 - 160 {mu}c (about 2 {mu}c/kg). The scanning examination starts about 2 h after the injection and lasts about 40-50 min. The selective storage of labelled Neohydrin at the level of the renal cortex makes it possible to obtain a graphic representation of the two kidneys and to identify their position, orientation and shape, and the homogeneity of the actively functioning parenchyma. In some cases, autoradiographic investigations have been carried out on diseased kidneys after surgical removal. By this method anomalies in position and orientation, both congenital and acquired, can be ascertained. As regards shape, the limits of the renal patterns are the mote clearly defined as the renal function is better. Technical aspects such as the width of the crystal, type of collimator (whose focal plane should pass through the transverse medial plane of the kidneys), and dose - which should be not too high not too low - are essential conditions for a correct graphic reproduction of the renal patterns. Failure in tabular activity in the parenchyma is shown by a lack in the uptake of radioactivity. The position, extent and shape of such defects in uptake vary according to the entity of the renal structures and their derangement due to various pathological processes: tumours, cysts, hydronephrosis, tuberculosis etc. In normal subjects a homogeneous scintigram is usual, although a clearer hilar region is not a rare occurrence. Any circumscribed decrease of scintigraphic density outside the hilum is the expression of a less actively functioning zone. Among kidney patterns larger than normal, the homogeneous ones which point to a compensatory hypertrophy should be distinguished from the dishomogeneous and irregular ones. These last pictures suggest the presence of large hydronephroses, tumours or multiple cysts. In renal vascular disease, the character of the uptake in the two kidneys can be of significant value in assessing the reduced function and in differentiating unilateral from bilateral diseases. Renal scintiscanning thus shows promise of proving a useful clinical technique, particularly if combined with radiological examination of the kidneys by traditional means (urography, ascending pyelography, retropneumoperitoneum, tomography, aortography, etc.). (author) [French] Les auteurs ont procede a des scintigraphies du rein au moyen de neohydrine marquee avec {sup 203}Hg. Ils ont utilise le dispositif de scintigraphie 'NuclearChicago', type 1700, a cristal de 5 x 5 cm et collimateur alveolaire de 7 cm de distance focale. En general, les scintigrammes sont enregistres a la fois sur papier et sur film photographique; la neohydrine marquee avec {sup 203}Hg est administree en doses de 120 a 160 {mu}c (environ 2 {mu}c/kg). L'examen scintigraphique commence deux heures environ apres l'injection et dure de 40 a 50 min. Le fait que la neohydrine marquee se fixe selectivement au niveau du cortex renal permet d'obtenir une representation graphique des deux reins et de determiner leur position, leur orientation et leur forme, ainsi que le degre d'homogeneite du parenchyme normal. Dans certains cas, des examens autobiographiques ont ete effectues sur des reins malades, apres ablation. Cette methode permet de determiner les anomalies, congenitales ou acquises, dans la position et l'orientation des reins. En ce qui concerne la forme de l'organe, les contours de l'image du rein sont d'autant plus nets que la fonction renale est meilleure. Des caracteristiques techniques telles que la largeur du cristal, le type.de collimateur (dont le plan focal doit couper le plan median transversal des reins) et la dose (qui ne doit etre ni trop elevee ni trop faible) representent les conditions determinantes d'une reproduction graphique correcte de la structure renale. Une mauvaise fixation de la radioactivite denote une insuffisance de l'activite tubulaire dans le parenchyme. La position, l'etendue.et la forme des zones de mauvaise fixation varient suivant le degre d'integrite des structures renales et leur alteration sous l'effet de divers processus pathologiques: tumeurs, kystes, hydro- nephrose, tuberculose, etc. Chez des sujets normaux, le scintigramme est generalement homogene, bien qu'il ne soit pas rare d'observer une plus faible densite dans la region du hile. Toute tache plus claire en dehors du hile indique une zone ou la fonction renale n'est pas normale. Parmi les images du rein plus grandes que la normale, il convient d'etablir une distinction entre les images homogenes, qui denotent une hypertrophie compensatoire, et les images non homogenes et irregulieres. Ces dernieres semblent indiquer une forte uronephrose ou la presence de tumeurs ou de kystes multiples. Dans les affections reno-vasculaires, le caractere de la fixation de la radioactivite dans les deux reins peut beaucoup aider a evaluer la diminution de la fonction renale et a etablir si un seul rein ou les deux sont atteints. On peut donc s'attendre que la scintigraphie du rein constituera une methode interessante d'exploration clinique, surtout en association avec l'examen radiologique des reins par les methodes classiques (urographie, pyeiographie ascendante, retropneumoperitoine, tomo- graphie, aortographie, etc.). (author) [Spanish] Los autores han efectuado exploraciones centelleograficas del rinón empleando neohidrina marcada con {sup 203}Hg. Para ello, utilizaron el Nuclear Chicago Isotope Scanner, tipo 1100, con un cristal de 2 x 2 pulg y un colimador alveolar de 7 cm de distancia focal. Los centelleogramas se registran generalmente simultaneamente en papel y pelicula fotografica. La neohidrina marcada con {sup 203}Hg suele administrarse en dosis de 120 a 160 {mu}c (aproximadamente 2 {mu}/kg). La exploracion se empieza unas dos horas despues de la inyeccion y dura de 40 a 50 min. La concentracion selectiva de la neohidrina marcada en la corteza renal permite obtener una representacion grafica de ambos rinones, comprobar su posicion, orientacion y forma, y verificar la homogeneidad del parenquima en actividad. En algunos casos se han efectuado investigaciones autorradiograficas en rifiones despues de extirparlos quirurgicamente. Gracias a ese metodo se pueden determinar anomalias, congenitas o adquiridas, en la posicion y la orientacion. Por lo que respecta a la forma, los limites del diagrama quedan mas claramente definidos cuanto mejor es la funcion renal. Ciertas condiciones tecnicas tales como la anchura del cristal, el tipo de colimador (cuyo plano focal debe cortar el plano transversal mediano de los rinones) y la dosis (que no debe ser ni excesiva ni demasiado baja) son esenciales para obtener un centelleograma correcto. Las deficiencias en la actividad tubular del parenquima dificultan la captacion de radioactividad. La situacion, la extension y la forma de esos defectos de la captacion varian en funcion de las estructuras renales y segun los procesos patologicos que los determinan: tumores, quistes, hidronefrosis, tuberculosis, etc. Para las personas sanas se obtienen centelleogramas homogeneos, aunque no es raro que la region hilar aparezca mas clara. Cualquier disminucion circunscrita de la densidad centelleografica fuera del hilio indica una zcna de actividad atenuada. Cuando los rinones aparecen dilatados hay que distinguir entre los homogeneos, que indican una hipertrofia compensatoria, y los no homogeneos e irregulares. Estos ultimos sugieren la presencia de hidronefrosis extensas, de tumores o de quistes multiples. Cuando se trata de enfermedades vasculares, el caracter de la captacion en ambos rinones puede contribuir considerablemente a determinar una disminucion de la funcion renal y a diferenciar los casos unilaterales de los bilaterales. Asi, la centelleografia del rinon constituye al parecer una tecnica clinica de gran utilidad, especialmente si se combina con el examen radiologico por medios tradicionales (urogtafia, pielografia ascendente, retroneumoperitoneo, tomografia, aorto- grafia, etc.). (author) [Russian] Dlja scintilljacionnogo skenirovanija pochek ispol'zovalsja neogidrin, mechennyj rtut'ju-203. Byl primenen jaderncj Chikagskij izotopnyj skenner tipa 1700 s kristallom 5 h 5 sm i kollimator ''Hanikoum'' s fokusnym rasstojaniem 7 sm. Obychno scintigrammy registrirujutsja odnovremenno na bumage i na fotoplenke. Neogidrin, mechennyj rtut'ju-203, primenjaetsja obychno v dozah 120 - 160 mkkjuri (okolo 2 mkkjuri/kg). Skennirovanie nachinajut spustja 2 chasa posle in{sup e}kcii i prodolzhajut 40 - 50 minut. Selektivnoe skoplenie mechenogo neogidrina v korkovom sloe pochek daet vozmozhnost' poluchit' graficheskoe izobrazhenie obeih pochek i opredelit' ih polozhenie, orientaciju i formu, a takzhe gomogennost' aktivno funkcionirujushhej parenhimy. V nekotoryh sluchajah byli provedeny avtoradiograficheskie issledovanija porazhennyh pochek posle hirurgicheskogo udalenija. S pomoshh'ju takogo metoda mozhno diagnoscirovat' kak vrozhdennye, tak i priobretennye anomalii polozhenija i orientacii. Chto kasaetsja formy, to granicy pochek mozhno opredelit' tem tochnee, chem luchshe funkcioniruet pochka. Takie tehnicheskie aspekty, kak shirina kristalla, tip kollimatora (fokal'naja ploskost' kotorogo dolzhna prohodit' cherez srednjuju poperechnuju ploskost' pochek) i doza, kotoraja ne dolzhna byt' slishkom vysokoj ili slishkom maloj, sostavljajut sushhestvennoe uslovie dlja pravil'nogo graficheskogo vosproizvedenija ochertanij pochek. Narushenie dejatel'nosti kanal'cev v parenhime opredeljaetsja blagodarja narusheniju pogloshhenija radioaktivnosti. Polozhenie, razmery i forma takih defektov pogloshhenija kolebljutsja v sootvetstvii s harakterom pochechnoj struktury i ee narushenij vsledstvie razlichnyh patologicheskih processov: opuholej, kist, gidronefroza, tuberkuleza i t.d. U zdorovyh ljudej obychno poluchajut odnorodnye scintigrammy, hotja poluchenie bolee chetkoj oblasti vorot organa ne javljaetsja redkim sluchaem. Kakoe-libo ogranichennoe umen'shenie scintigraficheskoj plotnosti vne vorot predstavljaet soboj funkcionirujushhuju menee aktivno zonu. Pri bolee krupnyh razmerah pochek, po sravneniju s normal'nymi, sleduet otlichat' odnorodnye skennogrammy, kotorye ukazyvajut na kompensatornuju gipertrofiju, neodnorodnyh i imejushhih nepravil'nuju formu. Izobrazhenija jetih poslednih ukazyvajut na nalichie krupnyh uchastkov gidronefroza, opuholej ili mnozhestvennyh kist. Pri pochechnyh sosudistyh zabolevanijah opredelenie haraktera pogloshhenija v obeih pochkah predstavljaet bol'shuju cennost' dlja ocenki snizhenija ih funkcii i dlja razgranichenija odnostoronnih i dvustoronnih porazhenij. Takim obrazom, scintilljacionnoe skennirovanie pochek obeshhaet dat' poleznye klinicheskie metody, osobenno v sochetanii s radiologicheskim issledovaniem pochek tradicionnymi sredstvami (urografija, voshodjashhaja pijelografija, retropnevmoperitoneum, tomografija, aorto- grafija it.d,),. (author)

  3. Enhancement of tendon–bone healing via the combination of biodegradable collagen-loaded nanofibrous membranes and a three-dimensional printed bone-anchoring bolt

    Directory of Open Access Journals (Sweden)

    Chou YC

    2016-08-01

    Full Text Available Ying-Chao Chou,1,2 Wen-Lin Yeh,2 Chien-Lin Chao,1 Yung-Heng Hsu,1,2 Yi-Hsun Yu,1,2 Jan-Kan Chen,3 Shih-Jung Liu1,2 1Department of Mechanical Engineering, Chang Gung University, 2Department of Orthopedic Surgery, Chang Gung Memorial Hospital, 3Department of Physiology and Pharmacology, Chang Gung University, Taoyuan, Taiwan Abstract: A composite biodegradable polymeric model was developed to enhance tendon graft healing. This model included a biodegradable polylactide (PLA bolt as the bone anchor and a poly(D,L-lactide-co-glycolide (PLGA nanofibrous membrane embedded with collagen as a biomimic patch to promote tendon–bone interface integration. Degradation rate and compressive strength of the PLA bolt were measured after immersion in a buffer solution for 3 months. In vitro biochemical characteristics and the nanofibrous matrix were assessed using a water contact angle analyzer, pH meter, and tetrazolium reduction assay. In vivo efficacies of PLGA/collagen nanofibers and PLA bolts for tendon–bone healing were investigated on a rabbit bone tunnel model with histological and tendon pullout tests. The PLGA/collagen-blended nanofibrous membrane was a hydrophilic, stable, and biocompatible scaffold. The PLA bolt was durable for tendon–bone anchoring. Histology showed adequate biocompatibility of the PLA bolt on a medial cortex with progressive bone ingrowth and without tissue overreaction. PLGA nanofibers within the bone tunnel also decreased the tunnel enlargement phenomenon and enhanced tendon–bone integration. Composite polymers of the PLA bolt and PLGA/collagen nanofibrous membrane can effectively promote outcomes of tendon reconstruction in a rabbit model. The composite biodegradable polymeric system may be useful in humans for tendon reconstruction. Keywords: polylactide–polyglycolide nanofibers, PLGA, collagen, 3D printing, polylactide, PLA, bone-anchoring bolts, tendon healing

  4. Compound antimalarial ethosomal cataplasm: preparation, evaluation, and mechanism of penetration enhancement

    Directory of Open Access Journals (Sweden)

    Shen S

    2015-06-01

    Full Text Available Shuo Shen, Shu-Zhi Liu, Yu-Shi Zhang, Mao-Bo Du, Ai-Hua Liang, Li-Hua Song, Zu-Guang Ye Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China Abstract: Malaria is still a serious public health problem in some parts of the world. The problems of recurrence and drug resistance are increasingly more serious. Thus, it is necessary to develop a novel antimalarial agent. The objectives of this study were to construct a novel compound antimalarial transdermal nanosystem–ethosomal cataplasm, to investigate its characteristics and efficiency, and to systematically explore the penetration-enhancing mechanisms of ethosomal cataplasm. Artesunate-loaded ethosomes and febrifugine-loaded ethosomes were prepared, and their characteristics were evaluated. Drug-loaded ethosomes were incorporated in the matrix of cataplasm to form the compound antimalarial ethosomal cataplasm. With the help of ethosomal technology, the accumulated permeation quantity of artesunate significantly increased at 8 hours after administration, which was 1.57 times as much as that of conventional cataplasm. Soon after administration, the ethosomal cataplasm could make a large quantity of antimalarial drug quickly penetrate through skin, then the remaining drug in the ethosomal cataplasm could be steadily released. These characteristics of ethosomal cataplasm are favorable for antimalarial drugs to kill Plasmodium spp. quickly and prevent the resurgence of Plasmodium spp. As expected, the ethosomal cataplasm showed good antimalarial efficiency in this experiment. The negative conversion rates were 100% and the recurrence rates were 0% at all dosages. The mechanism of penetration enhancement of the ethosomal cataplasm was systematically explored using an optics microscope, polarization microscope, and transmission electron microscopy. The microstructure, ultrastructure, and birefringent structure in skin were observed. Data

  5. Dynamic Optically Multiplexed Imaging

    Science.gov (United States)

    2015-07-29

    Dynamic Optically Multiplexed Imaging Yaron Rachlin, Vinay Shah, R. Hamilton Shepard, and Tina Shih Lincoln Laboratory, Massachusetts Institute of...V. Shah, and T. Shih “Design Architectures for Optically Multiplexed Imaging,” in submission 9 R. Gupta , P. Indyk, E. Price, and Y. Rachlin

  6. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. M-H Shih. Articles written in Sadhana. Volume 34 Issue 3 June 2009 pp 421-437. A model for signal processing and predictive control of semi-active structural control system · M-H Shih W-P Sung Ching-Jong Wang · More Details Abstract Fulltext PDF. The theory for structural control has been ...

  7. Activation of the sonic hedgehog signaling pathway occurs in the CD133 positive cells of mouse liver cancer Hepa 1–6 cells

    Directory of Open Access Journals (Sweden)

    Jeng KS

    2013-08-01

    Full Text Available Kuo-Shyang Jeng,1 I-Shyan Sheen,2 Wen-Juei Jeng,2 Ming-Che Yu,3 Hsin-I Hsiau,3 Fang-Yu Chang,3 Hsin-Hua Tsai31Department of Surgery, Far Eastern Memorial Hospital, Taipei, 2Department of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University, 3Department of Medical Research, Far Eastern Memorial Hospital, Taipei, Taiwan, Republic of ChinaBackground: The important role of cancer stem cells in carcinogenesis has been emphasized in research. CD133+ cells have been mentioned as liver cancer stem cells in hepatocellular carcinoma (HCC. Some researchers have proposed that the sonic hedgehog (Shh pathway contributes to hepatocarcinogenesis and that the pathway activation occurs mainly in cancer stem cells. We investigated whether the activation of the Shh pathway occurs in CD133+ cells from liver cancer.Materials and methods: We used magnetic sorting to isolate CD133+ cells from mouse cancer Hepa 1–6 cells. To examine the clonogenicity, cell culture and soft agar colony formation assay were performed between CD133+ and CD133- cells. To study the activation of the Shh pathway, we examined the mRNA expressions of Shh, patched homolog 1 (Ptch-1, glioma-associated oncogene homolog 1 (Gli-1, and smoothened homolog (Smoh by real-time polymerase chain reaction of both CD133+ and CD133- cells.Results: The number (mean ± standard deviation of colonies of CD133+ cells and CD133- cells was 1,031.0 ± 104.7 and 119.7 ± 17.6 respectively. This difference was statistically significant (P < 0.001. Their clonogenicity was 13.7% ± 1.4% and 1.6% ± 0.2% respectively with a statistically significant difference found (P < 0.001. CD133+ cells and CD133– cells were found to have statistically significant differences in Shh mRNA and Smoh mRNA (P = 0.005 and P = 0.043 respectively.Conclusion: CD133+ Hepa 1–6 cells have a significantly higher colony proliferation and clonogenicity. The Shh pathway is activated in these

  8. Estimating Typhoon Rainfall over Sea from SSM/I Satellite Data Using an Improved Genetic Programming

    Science.gov (United States)

    Yeh, K.; Wei, H.; Chen, L.; Liu, G.

    2010-12-01

    Estimating Typhoon Rainfall over Sea from SSM/I Satellite Data Using an Improved Genetic Programming Keh-Chia Yeha, Hsiao-Ping Weia,d, Li Chenb, and Gin-Rong Liuc a Department of Civil Engineering, National Chiao Tung University, Hsinchu, Taiwan, 300, R.O.C. b Department of Civil Engineering and Engineering Informatics, Chung Hua University, Hsinchu, Taiwan, 300, R.O.C. c Center for Space and Remote Sensing Research, National Central University, Tao-Yuan, Taiwan, 320, R.O.C. d National Science and Technology Center for Disaster Reduction, Taipei County, Taiwan, 231, R.O.C. Abstract This paper proposes an improved multi-run genetic programming (GP) and applies it to predict the rainfall using meteorological satellite data. GP is a well-known evolutionary programming and data mining method, used to automatically discover the complex relationships among nonlinear systems. The main advantage of GP is to optimize appropriate types of function and their associated coefficients simultaneously. This study makes an improvement to enhance escape ability from local optimums during the optimization procedure. The GP continuously runs several times by replacing the terminal nodes at the next run with the best solution at the current run. The current novel model improves GP, obtaining a highly nonlinear mathematical equation to estimate the rainfall. In the case study, this improved GP described above combining with SSM/I satellite data is employed to establish a suitable method for estimating rainfall at sea surface during typhoon periods. These estimated rainfalls are then verified with the data from four rainfall stations located at Peng-Jia-Yu, Don-Gji-Dao, Lan-Yu, and Green Island, which are four small islands around Taiwan. From the results, the improved GP can generate sophisticated and accurate nonlinear mathematical equation through two-run learning procedures which outperforms the traditional multiple linear regression, empirical equations and back-propagated network

  9. A novel nanobody specific for respiratory surfactant protein A has potential for lung targeting

    Directory of Open Access Journals (Sweden)

    Wang SM

    2015-04-01

    Full Text Available Shan-Mei Wang,1,* Xian He,2,* Nan Li,1,* Feng Yu,3 Yang Hu,1 Liu-Sheng Wang,1 Peng Zhang,4 Yu-Kui Du,1 Shan-Shan Du,1 Zhao-Fang Yin,1 Ya-Ru Wei,1 Xavier Mulet,5 Greg Coia,6 Dong Weng,1 Jian-Hua He,3 Min Wu,7 Hui-Ping Li1 1Department of Respiratory Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 2School of Medicine, Suzhou University, SuZhou, 3Shanghai Institute of Applied Physics, Chinese Academy of Sciences, 4Department of Chest Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China; 5CSIRO (Commonwealth Scientific and Industrial Research Materials Science and Engineering, Clayton, 6CSIRO Materials Science and Engineering, Parkville, Melbourne, VIC, Australia; 7Department of Basic Sciences, University of North Dakota, Grand Forks, ND, USA *These authors contributed equally to this work Abstract: Lung-targeting drugs are thought to be potential therapies of refractory lung diseases by maximizing local drug concentrations in the lung to avoid systemic circulation. However, a major limitation in developing lung-targeted drugs is the acquirement of lung-specific ligands. Pulmonary surfactant protein A (SPA is predominantly synthesized by type II alveolar epithelial cells, and may serve as a potential lung-targeting ligand. Here, we generated recombinant rat pulmonary SPA (rSPA as an antigen and immunized an alpaca to produce two nanobodies (the smallest naturally occurring antibodies specific for rSPA, designated Nb6 and Nb17. To assess these nanobodies’ potential for lung targeting, we evaluated their specificity to lung tissue and toxicity in mice. Using immunohistochemistry, we demonstrated that these anti-rSPA nanobodies selectively bound to rat lungs with high affinity. Furthermore, we intravenously injected fluorescein isothiocyanate-Nb17 in nude mice and observed its preferential accumulation in the lung to other tissues, suggesting high

  10. Quality of life and cosmetic result of single-port access endoscopic thyroidectomy via axillary approach in patients with papillary thyroid carcinoma

    Directory of Open Access Journals (Sweden)

    Huang JK

    2016-07-01

    Full Text Available Jian-kang Huang,1 Ling Ma,2 Wen-hua Song,1 Bang-yu Lu,3 Yu-bin Huang,3 Hui-ming Dong1 1Department of Surgical Oncology, 2Department of Gynecologic Tumor, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, 3Department of Minimally Invasive Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China Background: Endoscopic thyroidectomy for minimally invasive thyroid surgery has been widely applied in the past decade. The present study aimed to evaluate the effects of single-port access transaxillary totally endoscopic thyroidectomy on the postoperative outcomes and functional parameters, including quality of life and cosmetic result in patients with papillary thyroid carcinoma (PTC.Patients and methods: Seventy-five patients with PTC who underwent endoscopic thyroidectomy via a single-port access transaxillary approach were included (experimental group. A total of 123 patients with PTC who were subjected to conventional open total thyroidectomy served as the control group. The health-related quality of life and cosmetic and satisfaction outcomes were assessed postoperatively.Results: The mean operation time was significantly increased in the experimental group. The physiological functions and social functions in the two groups were remarkably augmented after 6 months of surgery. However, there was no significant difference in the scores of speech and taste between the two groups at the indicated time of 1 month and 6 months. In addition, the scores for appearance, satisfaction with appearance, role-physical, bodily pain, and general health in the experimental group were better than those in the control group at 1 month and 6 months after surgery.Conclusion: The single-port access transaxillary totally endoscopic thyroidectomy is safe and feasible for the treatment of patients with PTC. The subjects who underwent this technique have a good perception of their general

  11. Computer-aided classification of lung nodules on computed tomography images via deep learning technique

    Directory of Open Access Journals (Sweden)

    Hua KL

    2015-08-01

    Full Text Available Kai-Lung Hua,1 Che-Hao Hsu,1 Shintami Chusnul Hidayati,1 Wen-Huang Cheng,2 Yu-Jen Chen3 1Department of Computer Science and Information Engineering, National Taiwan University of Science and Technology, 2Research Center for Information Technology Innovation, Academia Sinica, 3Department of Radiation Oncology, MacKay Memorial Hospital, Taipei, Taiwan Abstract: Lung cancer has a poor prognosis when not diagnosed early and unresectable lesions are present. The management of small lung nodules noted on computed tomography scan is controversial due to uncertain tumor characteristics. A conventional computer-aided diagnosis (CAD scheme requires several image processing and pattern recognition steps to accomplish a quantitative tumor differentiation result. In such an ad hoc image analysis pipeline, every step depends heavily on the performance of the previous step. Accordingly, tuning of classification performance in a conventional CAD scheme is very complicated and arduous. Deep learning techniques, on the other hand, have the intrinsic advantage of an automatic exploitation feature and tuning of performance in a seamless fashion. In this study, we attempted to simplify the image analysis pipeline of conventional CAD with deep learning techniques. Specifically, we introduced models of a deep belief network and a convolutional neural network in the context of nodule classification in computed tomography images. Two baseline methods with feature computing steps were implemented for comparison. The experimental results suggest that deep learning methods could achieve better discriminative results and hold promise in the CAD application domain. Keywords: nodule classification, deep learning, deep belief network, convolutional neural network

  12. Andrographolide suppresses thymic stromal lymphopoietin in phorbol myristate acetate/calcium ionophore A23187-activated mast cells and 2,4-dinitrofluorobenzene-induced atopic dermatitis-like mice model

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    Li CX

    2016-02-01

    Full Text Available Chun-xiao Li,* Hua-guo Li,* Hui Zhang,* Ru-hong Cheng, Ming Li, Jian-ying Liang, Yan Gu, Bo Ling, Zhi-rong Yao, Hong Yu Department of Dermatology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China *These authors contributed equally to this work Background: Atopic dermatitis (AD is one of the most common inflammatory cutaneous diseases. Thymic stromal lymphopoietin (TSLP has been demonstrated to be an important immunologic factor in the pathogenesis of AD. The production of TSLP can be induced by a high level of intracellular calcium concentration and activation of the receptor-interacting protein 2/caspase-1/NF-κB pathway. Andrographolide (ANDRO, a natural bicyclic diterpenoid lactone, has been found to exert anti-inflammatory effects in gastrointestinal inflammatory disorders through suppressing the NF-κB pathway. Objective: To explore the effect of ANDRO on the production of TSLP in human mast cells and AD mice model. Methods: We utilized enzyme-linked immunosorbent assay, real-time reverse transcription polymerase chain reaction analysis, Western blot analysis, and immunofluorescence staining assay to investigate the effects of ANDRO on AD. Results: ANDRO ameliorated the increase in the intracellular calcium, protein, and messenger RNA levels of TSLP induced by phorbol myristate acetate/calcium ionophore A23187, through the blocking of the receptor-interacting protein 2/caspase-1/NF-κB pathway in human mast cell line 1 cells. ANDRO, via oral or local administration, also attenuated clinical symptoms in 2,4-dinitrofluorobenzene-induced AD mice model and suppressed the levels of TSLP in lesional skin. Conclusion: Taken together, ANDRO may be a potential therapeutic agent for AD through suppressing the expression of TSLP. Keywords: atopic dermatitis, thymic stromal lymphopoietin, andrographolide, human mast cell

  13. A novel small peptide as an epidermal growth factor receptor targeting ligand for nanodelivery in vitro

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    Han CY

    2013-04-01

    Full Text Available Cui-yan Han,1,2 Li-ling Yue,2 Ling-yu Tai,1 Li Zhou,2 Xue-yan Li,2 Gui-hua Xing,2 Xing-gang Yang,1 Ming-shuang Sun,1 Wei-san Pan1 1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China; 2Qiqihar Medical University, Qiqihar, People’s Republic of China Abstract: The epidermal growth factor receptor (EGFR serves an important function in the proliferation of tumors in humans and is an effective target for the treatment of cancer. In this paper, we studied the targeting characteristics of small peptides (AEYLR, EYINQ, and PDYQQD that were derived from three major autophosphorylation sites of the EGFR C-terminus domain in vitro. These small peptides were labeled with fluorescein isothiocyanate (FITC and used the peptide LARLLT as a positive control, which bound to putative EGFR selected from a virtual peptide library by computer-aided design, and the independent peptide RALEL as a negative control. Analyses with flow cytometry and an internalization assay using NCI-H1299 and K562 with high EGFR and no EGFR expression, respectively, indicated that FITC-AEYLR had high EGFR targeting activity. Biotin-AEYLR that was specifically bound to human EGFR proteins demonstrated a high affinity for human non-small-cell lung tumors. We found that AEYLR peptide-conjugated, nanostructured lipid carriers enhanced specific cellular uptake in vitro during a process that was apparently mediated by tumor cells with high-expression EGFR. Analysis of the MTT assay indicated that the AEYLR peptide did not significantly stimulate or inhibit the growth activity of the cells. These findings suggest that, when mediated by EGFR, AEYLR may be a potentially safe and efficient delivery ligand for targeted chemotherapy, radiotherapy, and gene therapy. Keywords: EGFR, small peptide, tumor targeting, lung cancer, NLC

  14. PDGF-metronidazole-encapsulated nanofibrous functional layers on collagen membrane promote alveolar ridge regeneration

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    Ho MH

    2017-08-01

    Full Text Available Ming-Hua Ho,1 Hao-Chieh Chang,2,3 Yu-Chia Chang,3 Jeiannete Claudia,1 Tzu-Chiao Lin,2 Po-Chun Chang2,3 1Department of Chemical Engineering, College of Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; 2Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan; 3Department of Dentistry, National Taiwan University Hospital, Taipei, Taiwan Abstract: This study aimed to develop a functionally graded membrane (FGM to prevent infection and promote tissue regeneration. Poly(L-lactide-co-D,L-lactide encapsulating platelet-derived growth factor (PDLLA-PDGF or metronidazole (PDLLA-MTZ was electrospun to form a nanofibrous layer on the inner or outer surface of a clinically available collagen membrane, respectively. The membrane was characterized for the morphology, molecule release profile, in vitro and in vivo biocompatibility, and preclinical efficiency for alveolar ridge regeneration. The PDLLA-MTZ and PDLLA-PDGF nanofibers were 800–900 nm in diameter, and the thicknesses of the functional layers were 20–30 µm, with sustained molecule release over 28 days. All of the membranes tested were compatible with cell survival in vitro and showed good tissue integration with minimal fibrous capsule formation or inflammation. Cell proliferation was especially prominent on the PDLLA-PDGF layer in vivo. On the alveolar ridge, all FGMs reduced wound dehiscence compared with the control collagen membrane, and the FGM with PDLLA-PDGF promoted osteogenesis significantly. In conclusion, the FGMs with PDLLA-PDGF and PDLLA-MTZ showed high biocompatibility and facilitated wound healing compared with conventional membrane, and the FGM with PDLLA-PDGF enhanced alveolar ridge regeneration in vivo. The design represents a beneficial modification, which may be easily adapted for future clinical use. Keywords: tissue engineering, platelet-derived growth factor, metronidazole, alveolar process

  15. 1,3-Bis(2-chloroethyl-1-nitrosourea-loaded bovine serum albumin nanoparticles with dual magnetic resonance–fluorescence imaging for tracking of chemotherapeutic agents

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    Wei KC

    2016-08-01

    Full Text Available Kuo-Chen Wei,1 Feng-Wei Lin,2 Chiung-Yin Huang,1 Chen-Chi M Ma,3 Ju-Yu Chen,1 Li-Ying Feng,1 Hung-Wei Yang2 1Department of Neurosurgery, Chang Gung Memorial Hospital, School of Medicine, Chang Gung University, Taoyuan, 2Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, 3Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan, Republic of China Abstract: To date, knowing how to identify the location of chemotherapeutic agents in the human body after injection is still a challenge. Therefore, it is urgent to develop a drug delivery system with molecular imaging tracking ability to accurately understand the distribution, location, and concentration of a drug in living organisms. In this study, we developed bovine serum albumin (BSA-based nanoparticles (NPs with dual magnetic resonance (MR and fluorescence imaging modalities (fluorescein isothiocyanate [FITC]-BSA-Gd/1,3-bis(2-chloroethyl-1-nitrosourea [BCNU] NPs to deliver BCNU for inhibition of brain tumor cells (MBR 261-2. These BSA-based NPs are water dispersible, stable, and biocompatible as confirmed by XTT cell viability assay. In vitro phantoms and in vivo MR and fluorescence imaging experiments show that the developed FITC-BSA-Gd/BCNU NPs enable dual MR and fluorescence imaging for monitoring cellular uptake and distribution in tumors. The T1 relaxivity (R1 of FITC-BSA-Gd/BCNU NPs was 3.25 mM-1 s-1, which was similar to that of the commercial T1 contrast agent (R1 =3.36 mM-1 s-1. The results indicate that this multifunctional drug delivery system has potential bioimaging tracking of chemotherapeutic agents ability in vitro and in vivo for cancer therapy. Keywords: drug tracking, fluorescence imaging, MR imaging, BSA nanoparticles, cancer therapy

  16. The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation

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    Chen N

    2017-12-01

    Full Text Available Ning Chen,1 Xiao-yan Yang,1,2 Chang-e Guo,1 Xin-ning Bi,1 Jian-hua Chen,1 Hong-ying Chen,1 Hong-pin Li,1 Hong-ying Lin,1 Yu-jie Zhang1 1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 2Nanjing Sanhome Pharmaceutical Co., Ltd., Nanjing, China Abstract: Epiberberine (EPI is a novel and potentially effective therapeutic and preventive agent for diabetes and cardiovascular disease. To evaluate its potential value for drug development, a specific, sensitive and robust high-performance liquid chromatography-tandem mass spectrometry assay for the determination of EPI in rat biological samples was established. This assay was used to study the pharmacokinetics, bioavailability and excretion of EPI in rats after oral administration. In addition, a cocktail method was used to compare the inhibition characteristics of EPI on cytochrome P450 (CYP450 isoforms in human liver microsomes (HLMs and rat liver microsomes (RLMs. The results demonstrated that EPI was rapidly absorbed and metabolized after oral administration (10, 54 or 81 mg/kg in rats, with Tmax of 0.37–0.42 h and T1/2 of 0.49–2.73 h. The Cmax and area under the curve values for EPI increased proportionally with the dose, and the oral absolute bioavailability was 14.46%. EPI was excreted mainly in bile and feces, and after its oral administration to rats, EPI was eliminated predominantly by the kidneys. A comparison of the current half-maximal inhibitory concentration and Ki values revealed that EPI demonstrated an obvious inhibitory effect on CYP2C9 and CYP2D6. Furthermore, its effect was stronger in HLM than in RLM, more likely to be a result of noncompetitive inhibition. Keywords: epiberberine, bioavailability, excretion kinetics, CYP inhibition type

  17. Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles

    Directory of Open Access Journals (Sweden)

    Chen YC

    2015-12-01

    Full Text Available Ying-Chen Chen,* Chia-Yu Su,* Hua-Jun Jhan, Hsiu-O Ho, Ming-Thau Sheu School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan *These authors contributed equally to this work Abstract: To alleviate the inherent problems of amphotericin B (AmB, such as poor water solubility and nephrotoxicity, a novel self-assembling mixed polymeric micelle delivery system based on lecithin and combined with amphiphilic polymers, Pluronic®, Kolliphor®, d-alpha tocopheryl polyethylene glycol succinate, and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(poly(ethylene glycol-2000 (DSPE-PEG2K was developed. An optimal formulation (Ambicelles composed of AmB:lecithin:DSPE-PEG2K in a 1:1:10 weight ratio was obtained. The particle size, polydispersion index, drug encapsulation efficiency, and drug loading were 187.20±10.55 nm, 0.51±0.017, 90.14%, and 7.51%, respectively, and the solubility was increased from 0.001 to 5 mg/mL. Compared with that of Fungizone®, the bioavailability of Ambicelles administered intravenously and orally increased 2.18- and 1.50-fold, respectively. Regarding the in vitro cytotoxicity, Ambicelles had a higher cell viability than free AmB solution or Fungizone® did. With pretreatment of 50 µg/mL ethanolic extract of Taiwanofungus camphoratus followed by AmB to HT29 colon cancer cells, the 50% inhibitory concentration of AmB solution was 12 µg/mL, whereas that of Ambicelles was 1 µg/mL, indicating that Ambicelles exerted a greater synergistic anticancer effect. Keywords: amphotericin B, micelle, amphiphilic polymer, lecithin, DSPE-PEG

  18. Different-ligand boron complexes with gluconate-ions and pentaerythritol and gluconatoborates with B-O-B bridge bond. Raznoligandnye kompleksy bora s glyukonat-ionami i pentaehritritom i glyukonatoboraty s mostikovoj V-O-V svyaz'yu

    Energy Technology Data Exchange (ETDEWEB)

    Tel' zhenskaya, P N; Shvarts, E M; Vitola, I M [AN Latvijskoj SSR, Riga (USSR). Inst. Neorganicheskoj Khimii

    1990-01-01

    Borogluconates differing in structure of the complex dimeric borogluconate ion from the described earlier have been synthesized. The results of physicochemical measurements (chemical and thermal analysis, IR-spectroscopy, titration according to Fisher, conductometry) allowed to propose formulas for the studied compounds.

  19. 胡阿祥:《东晋南朝侨州郡县与侨流人口研究》%Axiang Hu, Dongjin Nanchao Qiao zhoujunxian yu qiaoliu renkou yanjiu

    Institute of Scientific and Technical Information of China (English)

    孔祥军

    2010-01-01

    @@ The epoch of the Wei, Jin and Southern and Northern dynasties was perhaps the most chaotic and complicated era in Chinese history, in terms of regime instability. Except for a short period of unification under the Western Jin, this era was marked by continuous division and confrontation. Accordingly, professional historians and amateur history lovers alike prefer to examine the unified and the powerful Han and Tang dynasties and are often unwilling to deal with this discordant and tumultuous time.However,the furious conflicts of this era actually promoted ethnic amalgamations,territorial exploits,cultural transmission and intellectual communication,therefore,an in-depth study of this period is not only worthwhile,but necessary.

  20. Potential denitrification rates of subsurface soil under paddy fields receiving ground water with high nitrate concentration; Konodo shosantai chisso gan`yu chikasui no ryunyusuru suiden kasodo ni okeru dacchitsu kassei

    Energy Technology Data Exchange (ETDEWEB)

    Toda, H [Shizuoka Agricultural Experiment Station, Shizuoka (Japan); Hidaka, S [Saitama Agricultural Experiment Station, Saitama (Japan)

    1996-02-10

    It is well known that the concentration of nitrate nitrogen in the surface water decreases as it flows downward in rice paddies irrigated with water high in nitrate nitrogen concentration. The decrease is attributed to absorption by rice plants and algae adherent thereto and denitrification in the reduction layer well developed in the rice paddy surface soil. In paddy fields downstream of the Kushibiki plateau in the northwestern part of Saitama Prefecture, it is occasionally observed that nitrate nitrogen concentration in the ground water decreases as it flows down (farther from the plateau) not only in the flooded period but also in the non-flooded period. This suggests that in the said paddy field denitrification takes place not only in the rice paddy surface layer soil but also in the lower layer soil. Under the circumstances, the denitrification rate in the rice paddy lower layer soil was measured using the acetylene inhibition method under anaerobic and added nitrate conditions. A denitrification rate of 0.4-46ngN/g{sup -1} wet soil/h{sup -1} was obtained from a 40-150cm deep layer soil, smaller by the order of 1-2 than that in the surface layer soil. This suggests that the lower layer soil contributes to denitrification. 17 refs., 3 figs., 1 tab.

  1. Pancreas Scanning with Se{sup 75}-Selenomethionine; Scintigraphie du Pancreas avec de la Selenomethionine Marquee au Selenium-75; Skennirovanie podzheludochnoj zhelezy s pomoshch'yu selenometionina, mechennogo Selenom-75; Exploracion del Pancreas con Selenometionina-{sup 75}Se

    Energy Technology Data Exchange (ETDEWEB)

    Blau, M. [Department of Nuclear Medicine, Roswell Park Memorial Institute, Buffalo, NY (United States)

    1964-10-15

    Amino-acids show a high degree of localization in the pancreas during the first few hours after administration. This specificity is related to the rapid synthesis and turnover of the digestive enzymes. Since none of the elements in the structure of amino-acids (C,H, N,0 and S) have suitable gamma-emitting isotopes, they cannot be used for scanning. Several I{sup 131} derivatives of amino-acids were prepared and tested, but the pancreas-localizing property of the original amino-acid was lost in every case. The chemical similarity of selenium and sulphur suggested that the selenium analogue of methionine might resemble methionine closely enough to take its place in protein synthesis. Se{sup 75} (halflife, 128 d; principal gamma-ray, 0.27 MeV) is suitable for scanning. Selenium-75-selenomethionine was prepared by yeast biosynthesis. The yeast was grown on a low sulphur medium containing high specific activity Se{sup 75} as selenite. After extraction with ether and hot trichloracetic acid, the protein residue was hydrolysed with hydrochloric acid The resulting amino-acid mixture was separated by column chromatography. Selenium-75-selenomethionine prepared in this manner showed biological properties of a natural aminoacid. The uptake in pancreas was about 7% of the administered dose and the concentration in a gramme of pancreas was seven times that in a gramme of liver. Blood and other organs had even lower uptakes. The clinical usefulness of pancreas scanning is now being evaluated. Tumours of the pancreas have been found as areas of decreased uptake. There is no concentration of selenomethionine in cases of acute pancreatitis. It is too early to give a statistical estimate of our ability to find tumours of the pancreas by this technique. The estimated total body dose from this procedure is less than 1 rad. The selenium dose is only a. few microgrammes and represents no toxicity hazard. (author) [Spanish] Los aminoacidos tienden a localizarse en el pancreas durante las primeras horas que siguen a su administracion. Esta especificidad esta relacionada con la rapidez de la sintesis y de la renovacion de las enzimas digestivas. Como ninguno de los elementos que componen los aminoacidos (C, H, N, O y S) tiene isotopos emisores de rayos gamma apropiados, no es posible recurrir a ellos para la exploracion centelleografica. Los autores prepararon y ensayaron varios derivados de aminoacidos marcados con 131I, pero en todos los casos comprobaron la desaparicion de la propiedad de localizarse en el pancreas caracteristica del aminoacido original. La semejanza qufmica entre el selenio y el azufre sugirio a los autores la posibilidad de que el analogo seleniado de la metionina se pareciese a esta lo suficiente para poder sustituirla en la sintesis proteica. El selenio-75 (periodo: 128 d; rayos gamma principales: 0,27 MeV) es adecuado para la exploracion. La selenometionina-75Se fue preparada biosinteticamente mediante levaduras. Estas levaduras se cultivaron en un medio con poco azufre que contenia de alta actividad especifica, en forma de selenito. El residuo protefnico extraido con eter y acido tricloracetico en caliente, se hidrolizo con acido clorhidrico. La mezcla de aminoacidos obtenida se separo por cromatografia en columna. La selenometionina-{sup 75} asi preparada tiene las propiedades biologicas de un aminoacido natural. El pancreas absorbio el 7%, aproximadamente, de la dosis administrada y la concentracion por gramo de tejido fue siete veces mayor en el pancreas que en el higado. Menor aun que en este fue la concentracion en la sangre y en otros Organos. Los autores estan ahora evaluando la utilidad clinica de la exploracion del pancreas. Han comprobado que los tumores del pancreas constituyen zonas de absorcion disminuida. En los casos de pancreatitis aguda no se produce concentracion de selenometionina. Seria prematuro estimar estadisticamente la posibilidad de aplicar esta tecnica para descubrir tumores del pancreas. Se estima que la dosis corporal total imputable a la aplicacion de este procedimiento es inferior a 1 rad. La dosis de selenio es de algunos microgramos solamente y no entrana ningun riesgo de toxicidad. (author) [Russian] Obnaruzhena vysokaja stepen' koncentracii aminokislot v podzheludochnoj zheleze v techenie pervyh neskol'kih chasov posle vvedenija. Jeta osobennost' svjazana s bystrym sintezom i krugooborotom pishhevaritel'nyh fermentov. Poskol'ku ni odin iz jelementov v strukture aminokislot (C,H,N i S) ne imeet sootvetstvujushhih gamma- izluchajushhih izotopov, ih nel'zja ispol'zovat' dlja skennirovanija. Byli podgotovleny i ispytany neskol'ko proizvodnyh aminokislot -jod-131, no v kazhdom sluchae terjalos' svojstvo ishodnoj aminokisloty sosredotochivat'sja v podzheludochnoj zheleze. Himicheskoe shodstvo selena i sery daet osnovanie schitat', chto selenovyj analog meteonina blizok k metioninu po stroeniju v dostatochnoj stepeni, chtoby zanjat' ego mesto pri sinteze belka. Selen-75 (period poluraspada 128 dnej, osnovnye dannye: gamma-luchi, 0,27 Mjev) prigoden dlja skennirovanija. Prigotavlivalsja selenometionin - selen-75 s pomoshh'ju biosinteza drozhzhej. Drozhzhi vyrashhivali na srede s nizkim soderzhaniem sery i vysokoj udel'noj aktivnost'ju selena-75 v vide selenita. Posle jekstragirovanija jefirom i gorjachej trihloruksusnoj kislotoj belkovyj ostatok podvergali gidrolizu s pomoshh'ju soljanoj kisloty. Rezul'tirujushhuju smes' aminokislot razdeljali metodom hromatografii na kolonke. Selenometionin -selen-75, podgotovlennyj takim obrazom, imel biologicheskie svojstva prirodnyh aminokislot. Pogloshhenie v podzheludochnoj zheleze sostavljalo okolo 7%vvedennoj dozy, a koncentracija na gramm podzheludochnoj zhelezy byla v 7 raz bol'she chem na gramm pecheni. Pogloshhenie v krovi i drugih organah bylo eshhe nizhe, pecheni. Pogloshhenie v krovi i drugih organah bylo eshhe nizhe. V nastojashhee vremja proizvoditsja klinicheskaja ocenka metodov skennirovanija podzheludochnoj zhelezy. Opuholi podzheludochnoj zhelezy predstavljali uchastki s men'shim pogloshheniem. Ne nabljudalos' koncentracii selenometionina v sluchajah ostrogo pankreatita. Eshhe slishkom rano davat' statisticheskuju ocenku jetogo metoda obnaruzhenija opuholej podzheludochnoj zhelezy. Predpolagaemaja obshhaja doza, poluchaemaja organizmom v rezul'tate jetoj procedury, sostavljaet menee 1 rada. Doza selena sostavljaet neskol'ko mikrogramm i ne predstavljaet opasnosti v otnoshenii toksichnosti. (author)

  2. Changed of the working capacity of CMOS integrated circuits under ionizing radiations effect of low and high dose rate; Izmeneniya rabotosposobnosti KMOP integral`nykh mikroskhem pri vozdejstvii ioniziruyushchikh izluchenij s nizkoj i vysokoj intensivnost`yu

    Energy Technology Data Exchange (ETDEWEB)

    Bogatyrev, Yu V; Korshunov, F P

    1994-12-31

    Results of experimental investigations into the working capacity of different types of integrated CMOS circuits under effect of electron and gamma radiation are presented. Methods for evaluating IC CMOS under low irradiation intensity using the microcircuit testing under hugh intensity or at increased temperature with regard to the processes of parameter reconstruction after irradiation are proposed.

  3. Pochekaev R.Yu. Chinggis Khan’s Great Yasa in the Mongol Empire and Chinggisid States of the 13th–14th centuries: Legal Code or Ideal “Law and Order”?

    Directory of Open Access Journals (Sweden)

    R.Yu. Pochekaev

    2016-12-01

    Full Text Available Research objective of the article is clarifying of the nature of the Greta Yasa of Chinggis Khan: was it legal code or set of specific edicts, regulations and principles? Research materials include Arabian and Persian historical sources which already were used by another researchers of the Great Yasa (D. Ayalon, D.O. Morgan, as well as new sources on the history of the Mongol Empire, the Golden Horde, Yuan Empire, Chaghataid state recently introduced into scholarly circulation. Research results of the article consist in getting of arguments that the Great Yasa, in fact, was a set of specific principles and rules established by Chinggis Khan, and their observance provided a harmony in the Mongol Empire and the states of Chinggisids, i.e. the Great Yasa was a kind of “law and order” but not a legal code. Research novelty of the article is represented by analysis of the level of the legal development of the Mongols of the 13th–14th cc. when they didn’t need a special codification to regulate their legal relations, that’s why no one authentic source mentioned the Great Yasa as code of laws and it is characterized in this way only by representatives of the “written legal culture” (European, Caucasus, Arabian, etc..

  4. Relationship between surface structure of silicon containing steel and adhesion of hot dip galvanized coating; Si gan'yu koban no hyomen kozo to yoyu aen mekki micchakuseino kankei

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchiya, Y.; Hashimoto, S.; Ishibashi, Y. [Kokan Keisoku K.K., Kawasaki (Japan); Inagaki, J. [NKK Corp., Tokyo (Japan); Fukuda, Y. [Shuibuoka University, Shizuoka (Japan)

    2000-06-01

    The surface of the annealed steel and the exfoliated interface of the coating for the hot dip galvanized Si containing steel sheets was characterized by using SEM (Scanning Electron Microscope), AES (Auger Electron Spectroscopy) and TEM (Transmission Electron Microscopy). The adhesion of the coatings have depended on the Si content of the steel. It have been found that MnSiO{sub 3} particles are formed at the surface of the annealed steels having high Si content and that two types of grain having different distribution of the oxide exist in the steels. Large oxide particles have been formed in one type of grain and small particles are formed in the other type of grain. The different type of Fe-Zn alloy are formed on two types of grains. It have been observed that the oxide particles exist at the interface of exfoliated coatings after the adhesion test for the steels with high Si content. The distribution of the oxide particles observed at the bottom of the exfoliated coating is quite similar to that of the surface oxide of the annealed steel. From these results, the exfoliation of the coating has initiated at the oxide particles of the steel surface that has been not reduced during the hot dip galvanizing. (author)

  5. Fitter. The package for fitting a chosen theoretical multi-parameter function through a set of data points. Application to experimental data of the YuMO spectrometer. Version 2.1.0. Long write-up and user's guide

    International Nuclear Information System (INIS)

    Solov'ev, A.G.; Stadnik, A.V.; Islamov, A.N.; Kuklin, A.I.

    2008-01-01

    Fitter is a C++ program aimed to fit a chosen theoretical multi-parameter function through a set of data points. The method of fitting is chi-square minimization. Moreover, the robust fitting method can be applied to Fitter. Fitter was designed to be used for a small-angle neutron scattering data analysis. Respective theoretical models are implemented in it. Some commonly used models (Gaussian and polynomials) are also implemented for wider applicability

  6. Problems of the agriculture radiology and radiobiology at the environment contamination by the young mixture of the nuclear fission products; Problemy sel'skokhozyajstvennoj radioehkologii i radiobiologii pri zagryaznenii okruzhayushchej sredy molodoj smes'yu produktov yadernogo deleniya

    Energy Technology Data Exchange (ETDEWEB)

    Prister, B S

    2008-07-01

    The basic problem on population radiation safety and the farm production at the environment contamination by the young mixture of the nuclear fission products are considered. In the field experiments, the conformities of the out of root plant contamination, kinetics of the irradiation absorbed doses and the biological effect of the NFP on the plants during the different ontogenesis phases are investigated. The kinetics of the nuclear fission product accumulation and drawing out from the cattle organisms of the most movable radionuclides in the biological systems; the distribution and kinetics of the absorbed irradiation doses formation and the nuclear fission products biological effect on the cattle organism is studied. The comparative quantitative assessment of the meaning of the basic formation factors of the radiation situation is produced.

  7. Synthesis of Graft Copolymers by Small Doses of Irradiation; Synthese des copolymeres greffes au moyen de petites doses de rayonnements; Sintez privitykh sopolimerov s pomoshch'yu malykh doz oblucheniya; Sintesis de copolimeros de injerto mediante pequenas dosis de radiacion

    Energy Technology Data Exchange (ETDEWEB)

    Dobo, J; Somogyi, M; Kiss, L

    1960-07-15

    In addition to grafting, there is often an undesirable alteration in the properties of the original polymer when polymer monomer mixtures are irradiated. As a result of irradiation, grafting occurs not only on the original polymeric backbone, but also on the already grafted side-chains. The result is an acceleration of grafting. The effect is especially pronounced in the case of preformed polymers, if irradiation is carried out intermittently. The grafting of styrene can be accelerated by the addition of some solvents which suppress the protective effect of the styrene on the polymer. Grafting can be accelerated by other additives. The swelling properties of the irradiated films were investigated. (author) [French] Lorsque des melanges de polymeres et de monomeres sont soumis a des rayonnements, il se produit souvent, en meme temps que la greffe, une alteration facheuse des proprietes du polymere original. L'irradiation provoque une reaction de greffage, non seulement sur le polymere original, mais aussi sur les chaines laterales deja greffees. Il en resulte une acceleration du processus de greffage. L'effet est particulierement marque dans le cas des polymeres preformes, lorsque l'irradiation est effectuee par intermittence. On peut accelerer le processus de greffage du styrolene en ajoutant certains solvants qui suppriment l'action protectrice du styrolene sur le polymere. On peut aussi accelerer le processus a l'aide d'autres additifs. Les auteurs ont etudie les proprietes de gonflement des pellicules irradiees. (author) [Spanish] Simultaneamente con el injerto, bajo la accion de las radiaciones se produce frecuentemente una alteracion de las propiedades del polimero original, efecto que convendria evitar. Por lo tanto, quiza ofrezcan interes los elevados grados de injerto obtenidos en nuestros laboratorios con pequenas dosis de radiacion. La irradiacion no solo provoca una reaccion de injerto en la estructura polimerica original, sino tambien en las cadenas laterales injertadas. Ello se traduce en una aceleracion, del proceso de injerto. Este efecto es especialmente pronunciado en el caso de los polimeros preformados, cuando la irradiacion es intermitente. El injerto de las moleculas de estireno puede acelerarse anadiendo algunos solventes que suprimen la accion protectora ejercida por el estireno sobre el polimero. Asimismo, el proceso puede acelerarse agregando otras sustancias. Al injertar moleculas de metacrilato de metilo en el polietileno, hemos conseguido un injerto de 6 400 por ciento con una dosis de 31 400 roentgens. Hemos examinado la estructura de los copolimeros asi obtenidos. (author) [Russian] Grafting (privivanie ) chasto soprovozhdaetsya nezhelatel'nym izmeneniem svojstv pervonachal'nogo polimera pri obluchenii monomernykh smesej polimera. Pod vozdejstviem oblucheniya grafting proiskhodit ne tol'ko v pervonachal'noj polimernoj osnove, no takzhe v bokovoj tsepi, uzhe podvergnuvshejsya graftingu. Grafting v rezul'tate ehtogo uskoryaetsya. EHtot ehffekt osobenno yarko vyrazhen v tverdykh polimerakh, esli obluchenie proizvoditsya periodicheski. Grafting stirola mozhet byt' uskoren dobavleniem nekotorykh rastvoritelej, kotorye blokiruyut zashchitnoe vozdejstvie stirola na dannyj polimer. Grafting mozhet byt' uskoren i drugimi additivami. Issleduyutsya kachestva nabukhaniya obluchennoj plenki. (author)

  8. Disinfestation of Dried Figs by Gamma Radiation; Desinsectation des figues seches par les rayons gamma; Dezinfestatsiya sushenogo inzhira s pomoshch'yu gamma-izlucheniya'; Desinfestacion de higos secos mediante rayos gamma

    Energy Technology Data Exchange (ETDEWEB)

    Papadopoulou, C. P. [Department of Biology, Democritus Nuclear Research Centre, Aghia Paraskevi, Attica (Greece)

    1963-09-15

    Research has been carried on for many years on the disinfestation of stored agricultural products. Recently gamma radiation has been successfully applied in such investigations. Dried figs are among the main export products of Greece. Serious damage is caused by insect attack each year. The research work aimed at: (1) Determining the doses of radiation required to destroy certain species of insects attacking dried figs at their various stages of development, or to destroy their eggs and thus prevent reproduction; and (2) Determining the physical and chemical changes of the texture of dried figs caused by radiation. Studies have been made on the following species: Plodia interpunctella, Ephestia cautella, Carpophilus hemipterous, Oryzaephilus surinamensis and Lasioderma serricorne. The optimum doses required are discussed. At these doses, irradiation damage does not become apparent in the texture of the figs. (author) [French] Des recherches sur la desinsectation des produits agricoles en magasin sont en cours depuis de nombreuses annees. On a recemment utilise avec succes les rayons gamma dans ces etudes. Les insectes font chaque annee de grands ravages dans les figues seches, qui sont l'un des principaux produits d'exportation de la Grece. L'objet des recherches etait le suivant: 1. Determiner les doses de rayonnements necessaires pour detruire certaines especes d'insectes qui, a differents stades de leur developpement, attaquent les figues, ou detruire leurs oeufs et les empecher ainsi de se reproduire; 2. Determiner les modifications physiques et chimiques que les rayonnements produisent dans la texture de la figue seche. Les travaux ont porte sur les especes suivantes: Plodia interpunctella, Ephestia cautella, Carpophilus hemipterous, Oryzaephilus surinamensis et Lasioderma serricorne. Le memoire etudie les dises optimum d'irradiation, qui ne provoquent aucun dommage visible dans la texture de la figue. (author) [Spanish] Des hace muchos anos se estan efectuando investigaciones sobre la desinfestacion de los productos agricolas almacenados. En esas investigaciones se han utilizado recientemente con exito los rayos gamma. Los higos secos constituyen uno de los principales productos de exportacion de Grecia y los insectos ocasionan perdidas importantes. Las investigaciones tenian las siguientes finalidades: a) determinar las dosis de radiacion necesarias para destruir ciertas especies de insectos que atacan los higos en diversas fases de su desarrollo, o destruir sus huevos impidiendo asi que se reproduzcan; b) determinar las modificaciones fisicas y quimicas que las radiaciones producen en la contextura de los higos secos. Se han estudiado las especies siguientes: Plodia interpunctella, Ephestia cautella, Carpophilushemipterous, Oryzaephilus surinamensis y Lasioderma serricorne. En la memoria se estudian las dosis optimas de radiacion que no producen dafios aparentes en la contextura de los higos. (author) [Russian] V techenie mnogikh let provodyatsya issledovaniya to voprosam dezinfestatsii sel'skokhozyajstvennykh produktov v khranilishchakh. Nedavno gamma-izluchechie bylo uspeshno primeneno pri provedenii takikh issledovanij. Sushenyj inzhir sostavlyaet odin iz osnovnykh produktov ehksporta Gretsii. Ezhegodno nasekomye nanosyat ser'eznyj ushcherb ehtomu produktu. Tsel' issledovaniya: 1) opredelenie doz izlucheniya, neobkhodimykh dlya unichtozheniya nekotorykh vidov nasekomykh, porazhayushchikh sushenyj inzhir, na razlichnykh stadiyakh ikh razvitiya, i dlya unichtozheniya ikh yaits i predotvrashcheniya takim obrazom ikh razmnozheniya; i 2) opredelenie fiziko-khimicheskikh izmenenij tekstury sushenogo inzhira pod dejstviem izlucheniya. Issledovaniya provodilis' so sleduyushchimi vidami: Plodia Interpunctella, Ephestia coutella, Carpophilus hemipterous, Gryzaephllus surinamensis i Lasioderma serricorne. Obsuzhdayutsya neobkhodimye optimal'nye dozy. Pri ehtikh dozakh ne nablyudaetsya vidimogo narusheniya tekstury inzhira pod dejstviem oblucheniya. (author)

  9. Achievement report for fiscal 2000 on development of technology related to new recycled products. Research and development of simultaneous recovery of chlorine contained in waste plastics and alkali contained in waste glass bottles; 2000 nendo shinki recycle seihin nado kanren gijutsu kaihatsu seika hokokusho. Hai plastic gan'yu enso to hai glass bin gan'yu alkali no doji kaishu ni kakawaru kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Researches have been made on a technology to have alkali contained in waste glass bottles reacted with chlorine contained in waste plastics to separate and remove salt, and reuse the residues as a resource for cement raw material. This paper summarizes the achievements in fiscal 2000. In the research, glass powder pulverized to 5 to 10 {mu} m, calcium carbonate, iron oxide, and alumina were used to prepare raw material for the ordinary Portland cement. Vinyl chloride pulverized to 3 mm was added into this cement raw material so that chlorine-alkali equivalent ration will be 1.0, and the material was sintered in a rotary kiln at 800 to 1,400 degrees C. As a result, it was discovered that salt is produced from the alkali in glass and the chlorine in vinyl chloride, whereas the produced salt volatilizes when heated to 1,200 degrees C or higher, and clinker containing low chlorine and alkali can be produced. The test result reveals that the control range of the chlorine and alkali ratio is from 1.0 to 1.1. The remaining problems are measures against carbon monoxide and dioxin contained in the exhaust gas, and treatment of dust containing salt. (NEDO)

  10. Nuclear Materials Management and its Relationship to Nuclear Safety and Criticality Control; La Gestion des Matieres Nucleaires et ses Rapports avec la Securite Nucleaire et le Controle de la Criticite; Obrashchenie s yadernymi materialami i ego svyaz' s yadernoj bezopasnost'yu i kontrolem nad kritichnost'yu; La Administracion de Materiales Nucleares y sus Relaciones con la Seguridad Nuclear y el Control de la Criticidad

    Energy Technology Data Exchange (ETDEWEB)

    Tingey, F. H. [Phillips Petroleum Company, Idaho Falls, ID (United States)

    1966-02-15

    The preclusion of those conditions which would result in an inadvertent collection of fissionable material in quantity, geometry and environment to produce a neutron chain reaction is of fundamental importance to all those actively engaged in the nuclear industry. It is of particular concern to those individuals who are. responsible for the handling, transfer and storage of the fissionable materials in the performance of their various tasks. These same people are part of the nuclear materials management (NMM) system. They are the individuals who are primarily responsible for generating and receiving the SS accountability data channelled through the NMM office and as such must depend upon that office for valid and timely information in discharging their responsibility. Basically the responsibility for preventing inadvertent criticality in any area of plant operation lies with line supervision. In devising preventative measures at least three different types of problems need be considered. These are: (a) The scientific or technical problems connected with evaluating the hazard presented by a proposed quality of fissile material in a given geometry and environment; (b) The engineering problems presented by the restrictions dictated from the scientific or technical considerations; (c) The purely administrative problems presented in implementing the restrictions and requirements imposed from the technical and engineering considerations. To assist the supervisor in the successful discharge of this responsibility, some organizations provide certain groups or committees specialized in particular areas. Usually the technical problems are submitted to criticality specialists, commonly called a Nuclear Safety Committee, who are familiar with the experimental data of critical systems and can by theoretical calculation extend this experience to the problems at hand. Support in the engineering problems is given by plant engineering groups made cognizant of the requirements dictated by the technical considerations and familiar with the operational limitations. The administrative problems are solved through procedural restrictions placed by the supervisor. The NMM office can be most valuable in further support to the supervisor in these activities. The primary responsibility of this office is to alert responsible supervision to potentially hazardous situations as indicated either from information made available through the routine processing of accountability data or from material balance calculations. Any information pertaining to criticality studies as requested from the NMM office must be accurate and precise. A vigorous inventory management policy must be pursued to lessen the problems presented by accumulation of fissile materials. Internal audit by the NMM staff of inventory holdings can also serve to verify adherence to safeguard procedures. A vigorous orientation programme can be implemented by the NMM staff in its dealing with those individuals handling nuclear materials to make them more aware of the hazards involved. The integration of the NMM group into the general criticality safeguard problems at the NRT and has provided an effective system for assisting the line supervision in discharging this very important responsibility. (author) [French] Il est essentiel pour tous ceux qui travaillent dans l'industrie nucleaire de savoir comment eviter que des matieres nucleaires ne se trouvent rassemblees en quantites, selon une geometrie ou dans un milieu tels qu'elles puissent donner lieu a une reaction neutronique en chaine. Ceci interesse tout particulierement ceux qui, dans l'exercice de leurs fonctions, sont responsables de la manipulation, du transfert et de l'entreposage des matieres fissiles. Ces memes personnes participent au systeme de gestion des matieres nucleaires. Elles ont au premier chef la responsabilite de fournir et de recevoir les donnees comptables par l'intermediaire du service de gestion des matieres nucleaires; elles dependent donc de ce service pour les renseignements precis dont elles ont besoin pour assumer leurs responsabilites. C'est en premier lieu a la personne chargee de la surveillance generale du circuit qu'il incombe de veiller a ce qu'en aucun point les matieres nucleaires ne puissent, par inadvertance, atteindre l'etat critique. Pour mettre au point des mesures preventives, il faut tenir compte d'au moins trois categories de problemes, a savoir: a) Les problemes scientifiques et techniques lies a l'evaluation des risques que presente une certaine quantite de matieres fissiles disposee selon une certaine geometrie dans un certain endroit; b) Les problemes materiels souleves par les restrictions qu'imposent les considerations scientifiques ou techniques; c) Les problemes purement administratifs a resoudre pour respecter les restrictions et les conditions particulieres imposees par les considerations techniques et materielles. Pour aider le responsable de la surveillance a s'acquitter de sa tache, certaines organisations prevoient des groupes ou des comites specialises dans des domaines particuliers. Les problemes techniques sont le plus souvent soumis a des specialistes de la criticite, generalement constitues en comites de securite nucleaire, qui connaissent bien les donnees experimentales des systemes critiques et peuvent, par le calcul, exploiter cette experience pour resoudre les problemes qui se posent. En ce qui concerne les problemes materiels, ils sont soumis a des groupes de techniciens que l'on met au courant des conditions particulieres qu'imposent les facteurs techniques et qui connaissent bien les limites de fonctionnement de l'installation. Quant aux problemes administratifs, le responsable de la surveillance se charge de les resoudre' en reglementant les activites en consequence. Le service de gestion des matieres nucleaires peut apporter une aide precieuse au responsable de la surveillance. C'est tout d'abord a ce service qu'il incombe d'alerter le service de surveillance en lui signalant les conditions presentant un danger potentiel qu'il a pu deceler par l'etude des donnees comptables ou par le bilan matieres. Tous les renseignements demandes au service de gestion des matieres nucleaires au sujet de la criticite doivent etre exacts et precis. Un systeme efficace de controle de l'inventaire doit etre applique pour limiter les problemes que pose l'accumulation de matieres fissiles. En faisant proceder par le personnel du service de gestion des matieres nucleaires a une verification interne des matieres consignees dans l'inventaire, on peut egalement s'assurer que les mesures de securite sont bien appliquees. Le service de gestion des matieres nucleaires peut aussi assurer la formation du personnel charge de la manipulation des matieres nucleaires afin de lui faire prendre devantage conscience des risques encourus. En associant le service de gestion des matieres nucleaires aux specialistes de la prevention des etats critiques, la National Reactor Testing Station (NRTS) dispose d'un systeme efficace pour faciliter la tache du responsable de la surveillance du circuit matieres. (author) [Spanish] Para las personas que desempenan funciones importantes en la industria nuclear es de suma importancia evitar las acumulaciones accidentales de material fisionable en cantidades, medios y disposiciones que puedan ocasionar una reaccion neutronica en cadena. Esto concierne especialmente a los encargados de la manipulacion, la transferencia y el almacenamiento de dichos materiales. Estas personas forman parte del sistema de administracion de materiales nucleares y son fundamentalmente responsables de facilitar y recibir, por conducto de los servicios de administracion, datos contables relativos a los materiales basicos y a los materiales fisionables especiales; para que puedan desempenar satisfactoriamente sus funciones, es preciso que los servicios dispongan de informacion valida en el momento oportuno. Basicamente, la prevencion de los accidentes de criticidad en cualquier etapa del funcionamiento de una planta es una de las funciones inherentes a la inspeccion de las operaciones. Al proyectar las medidas preventivas hay que considerar, por lo menos, tres grupos distintos de problemas: a) Los problemas cientificos y tecnicos relativos a la evaluacion de los riesgos que presenta la acumulacion de materiales fisionables en cantidades, disposiciones y medios determinados; b) Los problemas de ingenieria que plantean las restricciones basadas en consideraciones de caracter cientifico o tecnico; c) Los problemas puramente administrative' que suscitan las limitaciones impuestas por cuestiones tecnicas y de ingenieria. Para facilitar el desempeno de las funciones de los inspectores algunas organizaciones han constituido comites especializados en determinados aspectos de la cuestion. Por lo general, los problemas tecnicos se someten a especialistas en criticidad, comunmente agrupados en un comite de seguridad nuclear, quienes conocen los datos experimentales de los sistemas criticos y pueden por calculo teorico extender ese conocimiento a los problemas especificos de la planta. Para los problemas de ingenieria se cuenta con la cooperacion de los grupos de ingenieros, a los cuales se mantiene informados de las necesidades impuestas por consideraciones tecnicas y de las limitaciones operativas. Los problemas administrativos se resuelven mediante restricciones de procedimiento dictadas por el inspector. Los servicios de administracion de materiales nucleares pueden facilitar en gran medida las tareas de inspeccion. En primer lugar, estos servicios tienen el deber de alertar a los inspectores cuando la informacion de que disponen gracias a la sistematizacion de los datos contables o a calculos basados en el balance de materiales revela la existencia de una situacion que puede resultar peligrosa. Toda la informacion referente a cuestiones de criticidad facilitada por los servicios de administracion de materiales nucleares debe ser exacta y precisa. Es necesario seguir una politica rigida de administracion de existencias a fin de limitar los problemas que suscita la acumulacion de materiales fisionables. La comprobacion interna de las existencias por el personal de los servicios de administracion puede servir tambien para verificar si se aplican los procedimientos de salvaguardia. Este personal puede llevar a cabo una importante labor de orientacion informando a los encargados de manipular los materiales fisionables sobre los peligros que sus actividades implican. La orientacion de los servicios de administracion de materiales nucleares hacia los problemas relativos a la prevencion de la criticidad aumenta considerablemente la eficacia de las inspecciones. (author) [Russian] Dlja vseh, aktivno rabotajushhih v oblasti jadernoj promyshlennosti, chrezvychajno vazhno ne dopuskat' sozdanija takih uslovij, kotorye mogli by privesti k nepredusmotrennomu skopleniju rasshhepljajushhih materialov v takih kolichestvah, geometrii i okruzhenii, kotorye mogut vyzvat' cepnuju reakciju nejtronov. Jeto osobenno vazhno dlja teh, na kom lezhit otvetstvennost' za pogruzochno-razgruzochnye raboty, peremeshhenie i hranenie rasshhepljajushhihsja materialov v hode vypolnenija razlichnyh zadanij. Jeti-zhe lica vhodjat v sistemu administrativno-hozjajstvennogo ucheta jadernyh materialov. Na objazannosti jetih lic lezhit v pervuju ochered' otvetstvennost' za sostavlenie i poluchenie dannyh statisticheskoj otchetnosti, napravljaemyh cherez Upravlenie po administrativnohozjajstvennomu uchetu jadernyh materialov, i v kachestve takovyh pri vypolnenii svoih objazannostej oni dolzhny obrashhat'sja v ukazannoe Upravlenie za predostavleniem im pravil'noj i svoevremennoj informacii. V osnovnom otvetstvennost' za nedopushhenie nepredusmotrennoj kritichnosti v ljuboj zone jekspluatacii ustanovki lezhit na rukovoditele rabot. Pri vyrabotke predupreditel'nyh meroprijatij sleduet uchityvat' po men'shej mere tri razlichnyh vida problem, a imenno: a) problemy nauchnogo ili tehnicheskogo haraktera, svjazannye s opredeleniem stepeni opasnosti, voznikajushhej v rezul'tate sosredotochenija v opredelennoj geometrii i okruzhenii namechaemyh kolichestv rasshhepljajushhihsja materialov; b) tehnologicheskie problemy, vytekajushhie iz diktuemyh nauchnymi i tehnicheskimi soobrazhenijami ogranichenij; v) chisto administrativjaye problemy, voznikajushhie pri osushhestvlenii ogranichenij i trebovanij, nalagaemyh po tehnicheskim i tehnologicheskim soobrazhenijam. Dlja okazanija sodejstvija rukovoditelju v celjah uspeshnogo vypolnenija im jetih funkcij nekotorye organizacii sozdajut opredelennye gruppy ili komitety, specializirovannye v opredelennyh oblastjah. Obychno tehnicheskie problemy predstavljajutsja na rassmotrenie specialistov po kritichnosti, ob{sup e}dinjaemyh v tak nazyvaemye Komitety po jadernoj bezopasnosti, kotorye horosho oznakomleny s jeksperimental'nymi dannymi kriticheskih sistem i v sostojanii raschetnym putem primenit' svoj opyt k dannoj konkretnoj probleme. Pomoshh' v tehnicheskih voprosah predostavljaetsja tehnicheskim personalom predprijatija, oznakomlennym s trebovanijami, diktuemymi tehnicheskimi soobrazhenijami, i horosho osvedomlennym otnositel'no jekspluatacionnyh ogranichenij. Administrativnye problemy razreshajutsja putem nalagaemyh rukovoditelem procedurnyh ogranichenij. Upravlenie po administrativno-hozjajstvennomu uchetu jadernyh materialov mozhet okazyvat' rukovoditelju dal'nejshuju podderzhku v ego rabote v jetoj oblasti. Prezhde vsego i glavnym obrazom na jetom Upravlenii lezhit objazannost' svoevremenno preduprezhdat' rukovodjashhie organy o vozmozhnosti sozdanija opasnyh polozhenij, kotorye mogut vyjasnit'sja libo na osnovanii svedenij, postupajushhih v rezul'tate povsednevnoj obrabotki dannyh otchetnosti, libo na osnovanii material'nyh raschetnyh balansov. Ljubye zaprashivaemye ot Upravlenija po administrativno-hozjajstvennomu uchetu jadernyh materialov svedenija, kasajushhiesja izuchenija kritichnosti, dolzhny byt' pravil'nymi i tochnymi. Dlja oblegchenija polozhenija, voznikajushhego v rezul'tate nakoplenija rashhepljajushhihsja materialov, sleduet strogo osushhestvljat' raspolozhenie material'nymi zapasami. Dlja proverki sobljudenija pravil bezopasnosti mozhet sluzhit' vnutrennjaja revizija inventarnyh zapisej personalom Upravlenija po administrativno-hozjajstvennomu uchetu jadernyh materialov. Dlja lic, imejushhih delo s jadernymi materialami, personal jetogo upravlenija mozhet provodit' intensivnuju programmu obluchenija dlja luchshego ponimanija imi svjazannoj s kritichnost'ju opasnosti. Na nacional'noj reaktornoj ispytatel'noj stancii vkljuchenie personala jetogo Upravlenija v razreshenie obshhih problem kritichnosti privelo k sozdaniju jeffektivnoj organizacii po okazaniju pomoshhi rukovodstvu v vypolnenii otvetstvennoj raboty. (author)

  11. 从“辽燕旧界”到“华夷大界”——朝鲜人笔下的山海关意象%From "the Boundary Beween Liao and Yan" to "the Boundary Beween Hua and Yi" : Shanhaiguan as Described by Koreans in the Ming and Qing Dynasties

    Institute of Scientific and Technical Information of China (English)

    黄普基

    2012-01-01

    明朝时期,朝鲜人并无以山海关为界、关内外华夷不同的“分界”概念。但明清易代,政治局面的巨变促使朝鲜人大大地强化了华夷分界的意识,以致最终认定山海关为明晰的“界线”。具体而言,清时期朝鲜人对关内的种种自然、人文景观往往表现出令人惊叹的宽容和肯定;相反,对关外却持着过于苛刻的否定态度。然而,有趣的是,清时期朝鲜人对关内外分界意识逐渐强化之时,两地的文化差距实际上却在日益缩小。而且,关内永平府与关外辽西之间,其相似性甚至大于差异性。%The concept that Shanhaiguan was the boundary between Chinese and foreigners did not exist at all among Koreans in the Ming Dynasty, but the concept was greatly strengthened but great political changes during the Ming-Qing transition. Koreans was surprisingly tolerant and positive towards the natural and humane landscape inside the Pass, but was overly severe and negative towards the landscape outside the Pass in the Qing Dynasty. Interestingly, the cultural distinction between inside the Pass and outside the Pass was reduced day by day while the boundary conception was gradually being strengthened in the Qing Dynasty, even though the resemblance was more than the distinction between inside the Pass and outside the Pass.

  12. 研究/電子資源使用統計標準與規範之探討/陳雪華;許嘉珍;朱雅琦 | Study of the Electronic Resources Usage Statistics Standards and Guidelines/ Hsueh-Hua Chen;Chia-Chen Hsu;Ya-Chi Chu

    Directory of Open Access Journals (Sweden)

    陳雪華、許嘉珍、朱雅琦

    2007-04-01

    Full Text Available

    近年來,由於資訊科技的進步,圖書館中的電子資源數量快速增加,所佔預算金額比例也大幅增長。圖書館希望能夠透過評鑑電子資源的使用,以便能夠在電 子資源館藏發展等方面做出正確的決策。由於體認到電子資源使用統計之重要性,圖書館界與相關組織紛紛發展或修訂圖書館統計標準,增列電子資源使用統計的項 目以充分反映圖書館電子資源使用之狀況。本文主要採用文獻分析法以及內容分析法,收集探討並比較近軍來國內外電子資源使用統計之相關規範及標準,包含 ISO 2789、 ICOLC Guidelines、州ANSI/NISO Z39.7、CNS13151、ARL E-Metrlcs、E-Measures Project、以及Project COUNTER等。

    Recently, due to the advances of information technology, electronic resources are gradually replacing print resources as the largest consumer of library acquisition budgets. Logically, libraries want to evaluate the usage of electronic resources and incorporate the results into their decision making regarding electronic resource acquisition. Over these years, there is a general awareness among libraries to develop statistics standards and guidelines for library electronic resources usage. In this paper, literature review and content analysis methods are used to compare several library statistics standards, including: ISO 2789 、ICOLC Guidelines、ANSI/NISO Z39.7、CNS13151、ARL E-Metrics、E-Measures Project、and Project COUNTER etc.

    頁次:89-102

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. HUA WANG. Articles written in Bulletin of Materials Science. Volume 36 Issue 3 June 2013 pp 389-393. Effects of Bi doping on dielectric and ferroelectric properties of PLBZT ferroelectric thin films synthesized by sol–gel processing · Hua Wang Li Liu Ji-Wen Xu Chang-Lai Yuan ...

  14. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Hua-Hsien Chiu1 Yi-Ting Tseng2 Hui-Pin Hsiao3 Hui-Hua Hsiao3. Department of Biotechnology, Fooyin University, Kaohsiung 831, Taiwan; School of Medical and Health Science, Fooyin University, Kaohsiung 831, Taiwan; Faculty of Medicine, College of Medicine, and Kaohsiung Medical University Hospital, Kaohsiung ...

  15. Additive theory of prime numbers

    CERN Document Server

    Hua, L K

    2009-01-01

    Loo-Keng Hua was a master mathematician, best known for his work using analytic methods in number theory. In particular, Hua is remembered for his contributions to Waring's Problem and his estimates of trigonometric sums. Additive Theory of Prime Numbers is an exposition of the classic methods as well as Hua's own techniques, many of which have now also become classic. An essential starting point is Vinogradov's mean-value theorem for trigonometric sums, which Hua usefully rephrases and improves. Hua states a generalized version of the Waring-Goldbach problem and gives asymptotic formulas for the number of solutions in Waring's Problem when the monomial x^k is replaced by an arbitrary polynomial of degree k. The book is an excellent entry point for readers interested in additive number theory. It will also be of value to those interested in the development of the now classic methods of the subject.

  16. Real-world treatment patterns and opioid use in chronic low back pain patients initiating duloxetine versus standard of care

    Directory of Open Access Journals (Sweden)

    Andrews JS

    2013-11-01

    Full Text Available Jeffrey Scott Andrews,1 Ning Wu,2 Shih-Yin Chen,2 Xia Yu,2 Xiaomei Peng,1 Diego Novick1 1Global Health Outcomes, Eli Lilly and Company, Indianapolis, IN, USA; 2Evidera, Lexington, MA, USA Abstract: To describe the use of pain medications in patients with chronic low back pain (CLBP after initiating duloxetine or standard of care (SOC [muscle relaxants, gabapentin, pregabalin, venlafaxine, and tricyclic antidepressants] for pain management, pharmacy and medical claims from Surveillance Data, Inc (SDI Health were analyzed. Adult patients with CLBP who initiated duloxetine or SOC between November 2010 and April 2011 were identified. Treatment initiation was defined as no pill coverage for duloxetine or SOC in the previous 90 days. Included patients had no opioid use in the 90 days before initiation. Propensity score matching was used to select patients with similar baseline demographic and clinical characteristics for duloxetine and SOC cohorts. Compliance with index medication was assessed via medication possession ratio (MPR and proportion of days covered (PDC for 6 months after initiation. The proportion of patients receiving opioids and days on opioids after index date were assessed, and regression models were estimated to compare opioid use between cohorts. A total of 766 patients initiated duloxetine and 6,206 patients initiated SOC. After matching, 743 patients were selected for the duloxetine (mean age 57 years; female 74% and SOC (mean age 57 years; female 75% cohorts, respectively. Of the duloxetine cohort, 92% started on or below recommended daily dose (≤60 mg. The duloxetine cohort had significantly higher MPR (0.78 versus [vs] 0.60 and PDC (0.50 vs 0.31, were less likely to use opioids (45% vs 61%, and had fewer days on opioids (median 0 vs 7 days than the SOC cohort (all P < 0.001. After adjusting for demographic and clinical characteristics, the duloxetine cohort initiated opioids later than the SOC cohort (hazard ratio 0.77, 95

  17. Artificial Intelligence Learning Semantics via External Resources for Classifying Diagnosis Codes in Discharge Notes.

    Science.gov (United States)

    Lin, Chin; Hsu, Chia-Jung; Lou, Yu-Sheng; Yeh, Shih-Jen; Lee, Chia-Cheng; Su, Sui-Lung; Chen, Hsiang-Cheng

    2017-11-06

    extracted enough concepts to predict the diagnosis codes. Word embedding combined with a CNN showed outstanding performance compared with traditional methods, needing very little data preprocessing. This shows that future studies will not be limited by incomplete dictionaries. A large amount of unstructured information from free-text medical writing will be extracted by automated approaches in the future, and we believe that the health care field is about to enter the age of big data. ©Chin Lin, Chia-Jung Hsu, Yu-Sheng Lou, Shih-Jen Yeh, Chia-Cheng Lee, Sui-Lung Su, Hsiang-Cheng Chen. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 06.11.2017.

  18. Relationship between resistant hypertension and arterial stiffness assessed by brachial-ankle pulse wave velocity in the older patient

    Directory of Open Access Journals (Sweden)

    Chung CM

    2014-09-01

    Full Text Available Chang-Min Chung,1,2 Hui-Wen Cheng,2 Jung-Jung Chang,2 Yu-Sheng Lin,2 Ju-Feng Hsiao,2 Shih-Tai Chang,1 Jen-Te Hsu2,31School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, 2Division of Cardiology, Chang Gung Memorial Hospital, Chiayi, 3Department of Medicine, College of Medicine, Chang Gung University, Taoyuan County, TaiwanBackground: Resistant hypertension (RH is a common clinical condition associated with increased cardiovascular mortality and morbidity in older patients. Several factors and conditions interfering with blood pressure (BP control, such as excess sodium intake, obesity, diabetes, older age, kidney disease, and certain identifiable causes of hypertension are common in patients resistant to antihypertensive treatment. Arterial stiffness, measured by brachial-ankle pulse wave velocity (baPWV, is increasingly recognized as an important prognostic index and potential therapeutic target in hypertensive patients. The aim of this study was to determine whether there is an association between RH and arterial stiffness. Methods: This study included 1,620 patients aged ≥65 years who were referred or self-referred to the outpatient hypertension unit located at a single cardiovascular center. They were separated into normotensive, controlled BP, and resistant hypertension groups. Home BP, blood laboratory parameters, echocardiographic studies and baPWV all were measured. Results: The likelihood of diabetes mellitus was significantly greater in the RH group than in the group with controlled BP (odds ratio 2.114, 95% confidence interval [CI] 1.194–3.744, P=0.010. Systolic BP was correlated in the RH group significantly more than in the group with controlled BP (odds ratio 1.032, 95% CI 1.012–1.053, P=0.001. baPWV (odds ratio 1.084, 95% CI 1.016–1.156, P=0.015 was significantly correlated with the presence of RH. The other factors were negatively correlated with the existence of RH.Conclusion: In

  19. Periostin overexpression is associated with worse prognosis in nasopharyngeal carcinoma from endemic area: a cohort study

    Directory of Open Access Journals (Sweden)

    Wei YC

    2018-05-01

    Full Text Available Yu-Ching Wei,1,2 Sheau-Fang Yang,2,3 Shih-Lun Chang,4,5 Tzu-Ju Chen,5,6 Sung-Wei Lee,7 Hung-Sung Chen,1 Li-Ching Lin,8 Chien-Feng Li6,9,10 1Department of Pathology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan; 2Department of Pathology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; 3Department of Pathology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; 4Department of Otolaryngology, Chi Mei Medical Center, Tainan, Taiwan; 5Department of Optometry, Chung Hwa University of Medical Technology, Tainan, Taiwan; 6Department of Pathology, Chi Mei Medical Center, Tainan, Taiwan; 7Department of Radiation Oncology, Chi Mei Medical Center, Liouying, Tainan, Taiwan; 8Department of Radiation Oncology, Chi Mei Medical Center, Tainan, Taiwan; 9National Institute of Cancer Research, National Health Research Institute, Tainan, Taiwan; 10Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan Purpose: Nasopharyngeal carcinoma (NPC is a heterogeneous disease. We searched for genes that function in cell adhesion in GSE12452, a published transcriptomic database. We found that POSTN, which encodes periostin (POSTN, was significantly upregulated in NPC tumorigenesis. Herein, we sought to analyze the expression of POSTN and its prognostic significances in patients with NPC. Materials and methods: In this single-institution retrospective study, we determined and analyzed POSTN expression by immunohistochemistry and H-score method, respectively, in 124 patients with NPC. The results indicated that POSTN expression was correlated with the clinicopathologic features, disease-specific survival (DSS, distant metastasis-free survival (DMFS, and local recurrence-free survival (LRFS of NPC. We performed univariate and multivariate analyses to determinate the statistical significance. Results: High POSTN expression was significantly associated with lymph node metastasis

  20. Local sustained delivery of acetylsalicylic acid via hybrid stent with biodegradable nanofibers reduces adhesion of blood cells and promotes reendothelialization of the denuded artery

    Directory of Open Access Journals (Sweden)

    Lee CH

    2014-01-01

    Full Text Available Cheng-Hung Lee,1,2 Yu-Huang Lin,3 Shang-Hung Chang,1 Chun-Der Tai,3 Shih-Jung Liu,2 Yen Chu,4 Chao-Jan Wang,5 Ming-Yi Hsu,5 Hung Chang,6 Gwo-Jyh Chang,7 Kuo-Chun Hung,1 Ming-Jer Hsieh,1 Fen-Chiung Lin,1 I-Chang Hsieh,1 Ming-Shien Wen,1 Yenlin Huang81Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Linkou, 2Department of Mechanical Engineering, 3Graduate Institute of Medical Mechatronics, Chang Gung University, 4Laboratory of Cardiovascular Physiology, Division of Thoracic and Cardiovascular Surgery, 5Department of Medical Imaging and Intervention, 6Hematology-Oncology Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, 7Graduate Institute of Clinical Medicinal Sciences, Chang Gung University College of Medicine, Linkou, 8Department of Anatomical Pathology, Chang Gung Memorial Hospital, Linkou, Tao-Yuan, TaiwanAbstract: Incomplete endothelialization, blood cell adhesion to vascular stents, and inflammation of arteries can result in acute stent thromboses. The systemic administration of acetylsalicylic acid decreases endothelial dysfunction, potentially reducing thrombus, enhancing vasodilatation, and inhibiting the progression of atherosclerosis; but, this is weakened by upper gastrointestinal bleeding. This study proposes a hybrid stent with biodegradable nanofibers, for the local, sustained delivery of acetylsalicylic acid to injured artery walls. Biodegradable nanofibers are prepared by first dissolving poly(D,L-lactide-co-glycolide and acetylsalicylic acid in 1,1,1,3,3,3-hexafluoro-2-propanol. The solution is then electrospun into nanofibrous tubes, which are then mounted onto commercially available bare-metal stents. In vitro release rates of pharmaceuticals from nanofibers are characterized using an elution method, and a high-performance liquid chromatography assay. The experimental results suggest that biodegradable nanofibers

  1. Rheological and fractal characteristics of unconditioned and conditioned water treatment residuals.

    Science.gov (United States)

    Dong, Y J; Wang, Y L; Feng, J

    2011-07-01

    The rheological and fractal characteristics of raw (unconditioned) and conditioned water treatment residuals (WTRs) were investigated in this study. Variations in morphology, size, and image fractal dimensions of the flocs/aggregates in these WTR systems with increasing polymer doses were analyzed. The results showed that when the raw WTRs were conditioned with the polymer CZ8688, the optimum polymer dosage was observed at 24 kg/ton dry sludge. The average diameter of irregularly shaped flocs/aggregates in the WTR suspensions increased from 42.54 μm to several hundred micrometers with increasing polymer doses. Furthermore, the aggregates in the conditioned WTR system displayed boundary/surface and mass fractals. At the optimum polymer dosage, the aggregates formed had a volumetric average diameter of about 820.7 μm, with a one-dimensional fractal dimension of 1.01 and a mass fractal dimension of 2.74 on the basis of the image analysis. Rheological tests indicated that the conditioned WTRs at the optimum polymer dosage showed higher levels of shear-thinning behavior than the raw WTRs. Variations in the limiting viscosity (η(∞)) of conditioned WTRs with sludge content could be described by a linear equation, which were different from the often-observed empirical exponential relationship for most municipal sludge. With increasing temperature, the η(∞) of the raw WTRs decreased more rapidly than that of the raw WTRs. Good fitting results for the relationships between lgη(∞)∼T using the Arrhenius equation indicate that the WTRs had a much higher activation energy for viscosity of about 17.86-26.91 J/mol compared with that of anaerobic granular sludge (2.51 J/mol) (Mu and Yu, 2006). In addition, the Bingham plastic model adequately described the rheological behavior of the conditioned WTRs, whereas the rheology of the raw WTRs fit the Herschel-Bulkley model well at only certain sludge contents. Considering the good power-law relationships between the

  2. December 2016

    African Journals Online (AJOL)

    FOBUR

    subsequently received a single dose of intravenous tenectaplase and was .... Oral vitamin K antagonists such as warfarin have remained the .... embolism in a cancer patient with ... Shih WJ, Robinson MC, Huber C, Pulmano. C. Tc-99m MAA ...

  3. Unedited Version

    Indian Academy of Sciences (India)

    5

    Patient with Familial Norrie Disease: Bilateral Blindness and Leucocoria ..... Lin RC, Shih JC (2013) Monoamine oxidase A and A/B knockout mice display autistic-like ... spectrum in familial exudative vitreoretinopathy and Norrie disease with ...

  4. High Uric Acid Activates the ROS-AMPK Pathway, Impairs CD68 Expression and Inhibits OxLDL-Induced Foam-Cell Formation in a Human Monocytic Cell Line, THP-1

    Directory of Open Access Journals (Sweden)

    Chaohuan Luo

    2016-11-01

    Full Text Available Background/Aims: Hyperuricemia is part of the metabolic-syndrome cluster of abdominal obesity, impaired glucose tolerance, insulin resistance, dyslipidemia, and hypertension. Monocytes/macrophages are critical in the development of metabolic syndrome, including gout, obesity and atherosclerosis. However, how high uric acid (HUA exposure affects monocyte/macrophage function remains unclear. In this study, we investigated the molecular mechanism of HUA exposure in monocytes/macrophages and its impact on oxidized low-density lipoprotein (oxLDL-induced foam-cell formation in a human monocytic cell line, THP-1. Methods: We primed THP-1 cells with phorbol-12-myristate-13-acetate (PMA for differentiation, then exposed cells to HUA and detected the production of reactive oxygen species (ROS and analyzed the level of phospho-AMPKα. THP-1 cells were pre-incubated with Compound C, an AMPK inhibitor, or N-acetyl-L-cysteine (NAC, a ROS scavenger, or HUA before PMA, to assess CD68 expression and phospho-AMPKα level. PMA-primed THP-1 cells were pre-treated with oxLDL before Compound C and HUA treatment. Western blot analysis was used to examine the levels of phospho-AMPKα, CD68, ABCG1, ABCA1, cyclooxygenase-2 (COX-2 and NF-κB (p65. Flow cytometry was used to assess ROS production and CD68 expression in live cells. Oil-red O staining was used to observe oxLDL uptake in cells. Results: HUA treatment increased ROS production in PMA-primed THP-1 cells; NAC blocked HUA-induced oxidative stress. HUA treatment time-dependently increased phospho-AMPKα level in PMA-primed THP-1 cells. The HUA-induced oxidative stress increased phospho-AMPKα levels, which was blocked by NAC. HUA treatment impaired CD68 expression during cell differentiation by activating the AMPK pathway, which was reversed by Compound C treatment. Finally, HUA treatment inhibited oxLDL uptake in the formation of foam cells in THP-1 cells, which was blocked by Compound C treatment. HUA treatment

  5. Supramolecular micellar nanoaggregates based on a novel chitosan/vitamin E succinate copolymer for paclitaxel selective delivery

    Directory of Open Access Journals (Sweden)

    Lian H

    2011-12-01

    Full Text Available He Lian1, Jin Sun1, Yan Ping Yu1, Yan Hua Liu2, Wen Cao1, Yong Jun Wang1, Ying Hua Sun1, Si Ling Wang1, Zhong Gui He11School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 2Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, Ningxia, People's Republic of ChinaBackground: Nowadays, many cytotoxic anticancer drugs exhibit low solubility and poor tumor selectivity, which means that the drug formulation is very important. For example, in the case of paclitaxel (PTX, Cremophor EL® (BASF, Ludwigshafen, Germany needs to be used as a solubilizer in its clinical formulation (Taxol®, Bristol-Myers Squibb, New York, NY, although it can cause serious side effects. Nanomicellar systems are promising carriers to resolve the above problems, and the polymer chosen is the key element.Methods: In this study, a novel amphiphilic chitosan/vitamin E succinate (CS-VES copolymer was successfully synthesized for self-assembling polymeric micelles. Proton nuclear magnetic resonance spectroscopy and infrared were used to characterize the molecular structure of the copolymer. The PTX-loaded CS-VES polymeric micelles (PTX-micelles were characterized by dynamic light scattering, transmission electron microscopy, X-ray diffraction, and differential scanning calorimetry.Results: The critical micelle concentration of CS-VES was about 12.6 µg/mL, with the degree of amino group substitution being 20.4%. PTX-micelles were prepared by a nanoprecipitation/dispersion technique without any surfactant being involved. PTX-micelles exhibited a drug loading as high as 21.37% and an encapsulation efficiency of 81.12%, with a particle size ranging from 326.3 to 380.8 nm and a zeta potential of +20 mV. In vitro release study showed a near zero-order sustained release, with 51.06%, 50.88%, and 44.35% of the PTX in the micelles being released up to 168 hours at three drug loadings of 7.52%, 14.09%, and 21.37%, respectively. The cellular uptake

  6. High Uric Acid Induces Insulin Resistance in Cardiomyocytes In Vitro and In Vivo.

    Directory of Open Access Journals (Sweden)

    Li Zhi

    Full Text Available Clinical studies have shown hyperuricemia strongly associated with insulin resistance as well as cardiovascular disease. Direct evidence of how high uric acid (HUA affects insulin resistance in cardiomyocytes, but the pathological mechanism of HUA associated with cardiovascular disease remains to be clarified. We aimed to examine the effect of HUA on insulin sensitivity in cardiomyocytes and on insulin resistance in hyperuricemic mouse model. We exposed primary cardiomyocytes and a rat cardiomyocyte cell line, H9c2 cardiomyocytes, to HUA, then quantified glucose uptake with a fluorescent glucose analog, 2-NBDG, after insulin challenge and detected reactive oxygen species (ROS production. Western blot analysis was used to examine the levels of insulin receptor (IR, phosphorylated insulin receptor substrate 1 (IRS1, Ser307 and phospho-Akt (Ser473. We monitored the impact of HUA on insulin resistance, insulin signaling and IR, phospho-IRS1 (Ser307 and phospho-Akt levels in myocardial tissue of an acute hyperuricemia mouse model established by potassium oxonate treatment. HUA inhibited insulin-induced glucose uptake in H9c2 and primary cardiomyocytes. It increased ROS production; pretreatment with N-acetyl-L-cysteine (NAC, a ROS scavenger, reversed HUA-inhibited glucose uptake induced by insulin. HUA exposure directly increased the phospho-IRS1 (Ser307 response to insulin and inhibited that of phospho-Akt in H9C2 cardiomyocytes, which was blocked by NAC. Furthermore, the acute hyperuricemic mice model showed impaired glucose tolerance and insulin tolerance accompanied by increased phospho-IRS1 (Ser307 and inhibited phospho-Akt response to insulin in myocardial tissues. HUA inhibited insulin signaling and induced insulin resistance in cardiomyocytes in vitro and in vivo, which is a novel potential mechanism of hyperuricemic-related cardiovascular disease.

  7. Study of acupuncture for low back pain in recent 20 years: a bibliometric analysis via CiteSpace

    Directory of Open Access Journals (Sweden)

    Liang YD

    2017-04-01

    Full Text Available Yu-Dan Liang,1,* Ying Li,1,* Jian Zhao,2 Xiao-Yin Wang,3 Hui-Zheng Zhu,1 Xiu-Hua Chen1 1The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, 2Longgang District People’s Hospital of Shenzhen, Shenzhen, 3Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, People’s Republic of China *These authors contributed equally to this work Background: Acupuncture has been applied to relieve low back pain (LBP in many countries. However, a bibliometric analysis of the global use of acupuncture for LBP is rare.Objective: The aim of this study was to demonstrate the state of the art and trends concerning the global use of acupuncture for LBP in recent 20 years.Methods: Literature relating to acupuncture for LBP from 1997 to 2016 was retrieved from Web of Science. CiteSpace was used to analyze country/institution, cited journals, authors/cited authors, cited references, and keywords. An analysis of counts and centrality was used to reveal publication outputs, countries/institutions, core journals, active authors, foundation references, hot topics, and frontiers.Results: A total of 958 references were obtained, and the total number of publications continually increased over the investigated period. Journal articles (662 were the most frequently occurring document type. The most productive country and institution in this field was the USA (342 and Harvard University (47, respectively. The J Altern Complem Med (69 was the most productive journal, and Pain (636 was the most cocited journal, which reflected the nature of the research. The Haake’s (2007 article (cocitation counts: 130 and the Cherkin’s (2001 article (centrality: 0.59 were the most representative and symbolic references, with the highest cocitation number and centrality, respectively. Cherkin was the most influential author, with the highest number of publications of 25 and a cocitation number of 226. The four hot topics in acupuncture for

  8. Hyaluronic acid–nimesulide conjugates as anticancer drugs against CD44-overexpressing HT-29 colorectal cancer in vitro and in vivo

    Directory of Open Access Journals (Sweden)

    Jian YS

    2017-03-01

    Full Text Available You-Sin Jian,1 Ching-Wen Chen,1 Chih-An Lin,2 Hsiu-Ping Yu,1 Hua-Yang Lin,3 Ming-Yuan Liao,1 Shu-Huan Wu,1 Yan-Fu Lin,1 Ping-Shan Lai1,2,4,5 1Department of Chemistry, 2PhD Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, 3Preclinical Development Research Department, Holy Stone Healthcare Co., Ltd., Taipei, 4Research Center for Sustainable Energy and Nanotechnology, 5Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan Abstract: Carrier-mediated drug delivery systems are promising therapeutics for targeted delivery and improved efficacy and safety of potent cytotoxic drugs. Nimesulide is a multifactorial cyclooxygenase 2 nonsteroidal anti-inflammatory drug with analgesic, antipyretic and potent anticancer properties; however, the low solubility of nimesulide limits its applications. Drugs conjugated with hyaluronic acid (HA are innovative carrier-mediated drug delivery systems characterized by CD44-mediated endocytosis of HA and intracellular drug release. In this study, hydrophobic nimesulide was conjugated to HA of two different molecular weights (360 kDa as HA with high molecular weight [HAH] and 43kDa as HA with low molecular weight [HAL] to improve its tumor-targeting ability and hydrophilicity. Our results showed that hydrogenated nimesulide (N-[4-amino-2-phenoxyphenyl]methanesulfonamide was successfully conjugated with both HA types by carbodiimide coupling and the degree of substitution of nimesulide was 1%, which was characterized by 1H nuclear magnetic resonance 400 MHz and total correlation spectroscopy. Both Alexa Fluor® 647 labeled HAH and HAL could selectively accumulate in CD44-overexpressing HT-29 colorectal tumor area in vivo, as observed by in vivo imaging system. In the in vitro cytotoxic test, HA–nimesulide conjugate displayed >46% cell killing ability at a nimesulide concentration of 400 µM in HT-29 cells, whereas

  9. A systemic administration of liposomal curcumin inhibits radiation pneumonitis and sensitizes lung carcinoma to radiation

    Directory of Open Access Journals (Sweden)

    Shi HS

    2012-05-01

    Full Text Available Hua-shan Shi1,* Xiang Gao,1,3,* Dan Li,1,* Qiong-wen Zhang,1 Yong-sheng Wang,2 Yu Zheng,1 Lu-Lu Cai,1 Ren-ming Zhong,2 Ao Rui,1 Zhi-yong Li,1 Hao Zheng,1 Xian-cheng Chen,1 Li-juan Chen,11State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medicine School, Sichuan University, Chengdu, Sichuan, People's Republic of China; 2State Key Laboratory of Biotherapy and Department of Thoracic Oncology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China; 3Deparment of Pathophysiology, College of Preclinical and Forensic Medical Sciences, Sichuan University, Chengdu, People's Republic of China*These authors contributed equally to this workAbstract: Radiation pneumonitis (RP is an important dose-limiting toxicity during thoracic radiotherapy. Previous investigations have shown that curcumin is used for the treatment of inflammatory conditions and cancer, suggesting that curcumin may prevent RP and sensitize cancer cells to irradiation. However, the clinical advancement of curcumin is limited by its poor water solubility and low bioavailability after oral administration. Here, a water-soluble liposomal curcumin system was developed to investigate its prevention and sensitizing effects by an intravenous administration manner in mice models. The results showed that liposomal curcumin inhibited nuclear factor-κB pathway and downregulated inflammatory factors including tumor necrosis factor-α, interleukin (IL-6, IL-8, and transforming growth factor-β induced by thoracic irradiation. Furthermore, the combined treatment with liposomal curcumin and radiotherapy increased intratumoral apoptosis and microvessel responses to irradiation in vivo. The significantly enhanced inhibition of tumor growth also was observed in a murine lung carcinoma (LL/2 model. There were no obvious toxicities observed in mice. The current results indicate that liposomal curcumin can effectively

  10. Reevaluation of the post-marketing safety of Shuxuening injection based on real-world and evidence-based evaluations

    Directory of Open Access Journals (Sweden)

    Wang C

    2018-04-01

    Full Text Available Can Wang,1,2 Qing-ping Shi,1,2 Feng Ding,2 Xiao-dong Jiang,1,2 Wei Tang,3 Mei-Ling Yu,1,2 Jian-Hua Zhu2 1Department of Pharmacy, The First Affiliated Hospital of Bengbu Medical College, Bengbu, People’s Republic of China; 2Faculty of Pharmacy, Bengbu Medical College, Bengbu, People’s Republic of China; 3Department of Pharmacy, Huaiyuan County Hospital of TCM in Anhui, Bengbu, People’s Republic of China Aim: To evaluate the factors influencing suspected hypersensitivity and adverse systemic reactions after Shuxuening injection and to provide innovative ideas and methods for the reevaluation of post-marketing safety of Shuxuening.Methods: This study used a prospective, nested case–control study design, combined with a prescription sequence analysis design method. It classified patients who exhibited trigger signals after administration of Shuxuening injection as suspected allergic patients and made comparisons with patients who did not report adverse effects to calculate the correlation between relevant risk factors and suspected allergic reactions. Randomized controlled studies and cohort studies of the adverse drug reaction (ADR of Shuxuening were performed using a computer database. Data retrieval was carried out by the foundation governing the individual database. Meta-analysis was performed by using R3.2.3 software to evaluate the ADRs of Shuxuening.Results: The results of real-world study showed that administration of Shuxuening in combination with potassium aspartate and magnesium, atorvastatin calcium, Shengmai injection, pantoprazole sodium, or high-dose medication was a risk factor for suspected allergic reactions. Meta-analysis showed that the incidence of adverse events was 5.84% (95% CI 0.0499; 0.0674, and serious adverse reaction rate was 4.36% (95% CI 0.0188; 0.0760 when Shuxuening was used in combination with these drugs. The incidence of allergic reaction was also influenced by the vehicle, duration of treatment, single

  11. Topical ocular delivery to laser-induced choroidal neovascularization by dual internalizing RGD and TAT peptide-modified nanoparticles

    Directory of Open Access Journals (Sweden)

    Chu YC

    2017-02-01

    Full Text Available Yongchao Chu,1,* Ning Chen,2,* Huajun Yu,2,* Hongjie Mu,1 Bin He,1 Hongchen Hua,1 Aiping Wang,1 Kaoxiang Sun1 1School of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Yantai University, Yantai, Shandong, People’s Republic of China; 2Department of Ophthalmology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, People’s Republic of China *These authors contributed equally to this work Abstract: A nanoparticle (NP was developed to target choroidal neovascularization (CNV via topical ocular administration. The NPs were prepared through conjugation of internalizing arginine-glycine-aspartic acid RGD (iRGD; Ac-CCRGDKGPDC and transactivated transcription (TAT (RKKRRQRRRC peptide to polymerized ethylene glycol and lactic-co-glycolic acid. The iRGD sequence can specifically bind with integrin αvβ3, while TAT facilitates penetration through the ocular barrier. 1H nuclear magnetic resonance and high-performance liquid chromatography demonstrated that up to 80% of iRGD and TAT were conjugated to poly(ethylene glycol–poly(lactic-co-glycolic acid. The resulting particle size was 67.0±1.7 nm, and the zeta potential of the particles was −6.63±0.43 mV. The corneal permeation of iRGD and TAT NPs increased by 5.50- and 4.56-fold compared to that of bare and iRGD-modified NPs, respectively. Cellular uptake showed that the red fluorescence intensity of iRGD and TAT NPs was highest among primary NPs and iRGD- or TAT-modified NPs. CNV was fully formed 14 days after photocoagulation in Brown Norway (BN rats as shown by optical coherence tomography and fundus fluorescein angiography analyses. Choroidal flat mounts in BN rats showed that the red fluorescence intensity of NPs followed the order of iRGD and TAT NPs > TAT-modified NPs > iRGD-modified NPs

  12. Developing a Curriculum for Information and Communications Technology Use in Global Health Research and Training: A Qualitative Study Among Chinese Health Sciences Graduate Students.

    Science.gov (United States)

    Ma, Zhenyu; Yang, Li; Yang, Lan; Huang, Kaiyong; Yu, Hongping; He, Huimin; Wang, Jiaji; Cai, Le; Wang, Jie; Fu, Hua; Quintiliani, Lisa; Friedman, Robert H; Xiao, Jian; Abdullah, Abu S

    2017-06-12

    for a specialized curriculum related to ICT use in health research for health sciences graduate students in China. The results have important implications for the design and implementation of ICT-related educational program in China or other developing countries. ©Zhenyu Ma, Li Yang, Lan Yang, Kaiyong Huang, Hongping Yu, Huimin He, Jiaji Wang, Le Cai, Jie Wang, Hua Fu, Lisa Quintiliani, Robert H Friedman, Jian Xiao, Abu S Abdullah. Originally published in JMIR Medical Education (http://mededu.jmir.org), 12.06.2017.

  13. Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide

    Directory of Open Access Journals (Sweden)

    Lu YJ

    2012-03-01

    Full Text Available Yu-Jen Lu1,2,#, Hung-Wei Yang1,#, Sheng-Che Hung3, Chiung-Yin Huang2, Shin-Ming Li4, Chen-Chi M Ma4, Pin-Yuan Chen2, Hong-Chieh Tsai2, Kuo-Chen Wei2, Jyh-Ping Chen1 1Department of Chemical and Materials Engineering, Chang Gung University, Kwei-San, Taoyuan, Taiwan; 2Department of Neurosurgery, Chang Gung Memorial Hospital, Kwei-San, Taoyuan, Taiwan; 3Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan; 4Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan#These authors contributed equally to this workBackground: 1,3-bis(2-chloroethyl-1-nitrosourea (BCNU, a commercial chemotherapeutic drug for treating malignant brain tumors, has poor thermal stability and a short half-life. Immobilization of BCNU on a nanocarrier might increase the thermal stability of BCNU and extend its half-life.Methods: Nanosized graphene oxide (GO could be modified by polyacrylic acid (PAA to improve the aqueous solubility and increase the cell penetration efficacy of the nanocarrier. PAA–GO intended as a drug carrier for BCNU was prepared and characterized in this study. The size and thickness of PAA–GO was investigated by transmission electron microscopy and atomic force microscopy, and the presence of PAA functional groups was confirmed by electron spectroscopy for chemical analysis and thermogravimetric analysis. BCNU was conjugated to PAA–GO by covalent binding for specific killing of cancer cells, which could also enhance the thermal stability of the drug.Results: Single layer PAA–GO (about 1.9 nm with a lateral width as small as 36 nm was successfully prepared. The optimum drug immobilization condition was by reacting 0.5 mg PAA–GO with 0.4 mg BCNU, and the drug-loading capacity and residual drug activity were 198 µg BCNU/mg PAA–GO and 70%, respectively. This nanocarrier significantly prolonged the half-life of bound BCNU from 19 to 43 hours compared with free drug and showed efficient intracellular

  14. In vivo study of doxorubicin-loaded cell-penetrating peptide-modified pH-sensitive liposomes: biocompatibility, bio-distribution, and pharmacodynamics in BALB/c nude mice bearing human breast tumors

    Directory of Open Access Journals (Sweden)

    Ding Y

    2017-10-01

    Full Text Available Yuan Ding,1,* Wei Cui,2,* Dan Sun,1 Gui-Ling Wang,1 Yu Hei,1 Shuai Meng,1 Jian-Hua Chen,3 Ying Xie,1 Zhi-Qiang Wang4 1Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, 2School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, Beijing, 3School of Medicine, Jianghan University, Wuhan, People’s Republic of China; 4Department of Chemistry and Biochemistry, Kent State University Geauga, Burton, OH, USA *These authors contributed equally to this work Abstract: In vivo evaluation of drug delivery vectors is essential for clinical translation. In BALB/c nude mice bearing human breast cancer tumors, we investigated the biocompatibility, pharmacokinetics, and pharmacodynamics of doxorubicin (DOX-loaded novel cell-penetrating peptide (CPP-modified pH-sensitive liposomes (CPPL (referred to as CPPL(DOX with an optimal CPP density of 4%. In CPPL, a polyethylene glycol (PEG derivative formed by conjugating PEG with stearate via acid-degradable hydrazone bond (PEG2000-Hz-stearate was inserted into the surface of liposomes, and CPP was directly attached to liposome surfaces via coupling with stearate to simultaneously achieve long circulation time in blood and improve the selectivity and efficacy of CPP for tumor targeting. Compared to PEGylated liposomes, CPPL enhanced DOX accumulation in tumors up to 1.9-fold (p<0.01 and resulted in more cell apoptosis as a result of DNA disruption as well as a relatively lower tumor growth ratio (T/C%. Histological examination did not show any signs of necrosis or inflammation in normal tissues, but large cell dissolving areas were found in tumors following the treatment of animals with CPPL(DOX. Our findings provide important and detailed information regarding the distribution of CPPL(DOX in vivo and reveal their abilities of tumor penetration and potential for the treatment of

  15. NSLS 2003 ACTIVITY REPORT (NATIONAL SYNCHROTRON LIGHT SOURCE ACTIVITY REPORT 2003)

    International Nuclear Information System (INIS)

    MILLER, L.

    2004-01-01

    The scientific productivity of the NSLS continues to be outstanding and the research conducted here has high impact. 2003 was no exception and some of the many highlights from this year's research activity are included in this Activity Report. We are especially pleased that one of our users, Professor Roderick MacKinnon (Rockefeller University), was the co-recipient of the 2003 Nobel Prize in Chemistry for work, much of which was done at the NSLS, explaining how proteins known as ion channels help to generate nerve impulses. It is also a particular pleasure to note that NSLS accelerator physicist Li Hua Yu was awarded the 2003 International Free Electron Laser Prize in recognition of his outstanding achievements, especially demonstrating High Gain Harmonic Generation (HGHG) at the DUV-FEL. Our vision for the NSLS in the next five to 10 years is for it to continue to serve as a vital resource for the nation and especially for the strong Northeast research community. To accomplish this, we are working to preserve and enhance its outstanding scientific productivity by providing increased user support and upgrading beamline and endstation instrumentation. For example, this past year we collaborated with scientists from the Albert Einstein College of Medicine and the BNL Biology Department to develop a new undulator beamline, X29, to meet the needs of macromolecular crystallography for high brightness x-rays. A new endstation on the undulator beamline X13B is being equipped with optics and instrumentation for microdiffraction and microprobe experiments. The wiggler beamline, X21, is being upgraded to provide high intensity and increased capacity for small angle x-ray scattering experiments on nanotemplated soft matter, biomaterials, and other systems. We are collaborating with the BNL Center for Functional Nanomaterials to develop a beamline for LEEM/PEEM studies, which will add important new capabilities for nanoscience and catalysis research. A new high-speed, high

  16. Disturbed spontaneous brain activity pattern in patients with primary angle-closure glaucoma using amplitude of low-frequency fluctuation: a fMRI study

    Directory of Open Access Journals (Sweden)

    Huang X

    2015-07-01

    Full Text Available Xin Huang,1,* Yu-Lin Zhong,1,* Xian-Jun Zeng,2 Fuqing Zhou,2 Xin-Hua Liu,1 Pei-Hong Hu,1 Chong-Gang Pei,1 Yi Shao,1 Xi-Jian Dai21Department of Ophthalmology, 2Department of Radiology, The First Affiliated Hospital of Nanchang University, Nangchang, Jiangxi, People’s Republic of China*These authors contributed equally to this workObjective: The aim of this study is to use amplitude of low-frequency fluctuation (ALFF as a method to explore the local features of spontaneous brain activity in patients with primary angle -closure glaucoma (PACG and ALFFs relationship with the behavioral performances.Methods: A total of twenty one patients with PACG (eight males and 13 females, and twenty one healthy subjects (nine males and twelve females closely matched in age, sex, and education, each underwent a resting-state functional magnetic resonance imaging scan. The ALFF method was used to assess the local features of spontaneous brain activity. The correlation analysis was used to explore the relationships between the observed mean ALFF signal values of the different areas in PACG patients and the thickness of the retinal nerve fiber layer (RNFL. Results: Compared with the healthy subjects, patients with PACG had significant lower ALFF areas in the left precentral gyrus, bilateral middle frontal gyrus, bilateral superior frontal gyrus, right precuneus, and right angular gyrus, and higher areas in the right precentral gyrus. In the PACG group, there were significant negative correlations between the mean ALFF signal value of the right middle frontal gyrus and the left mean RNFL thickness (r=-0.487, P=0.033, and between the mean ALFF signal value of the left middle frontal gyrus and the right mean RNFL thickness (r=-0.504, P=0.020. Conclusion: PACG mainly involved in the dysfunction in the frontal lobe, which may reflect the underlying pathologic mechanism of PACG.Keywords: angle-closure glaucoma, amplitude of low-frequency fluctuation, functional

  17. Codelivery of curcumin and doxorubicin by MPEG-PCL results in improved efficacy of systemically administered chemotherapy in mice with lung cancer

    Directory of Open Access Journals (Sweden)

    Wang BL

    2013-09-01

    Full Text Available Bi-Lan Wang,1,* Yong-mei Shen,1,3,* Qiong-wen Zhang,1,* Yu-li Li,1 Min Luo,1 Ze Liu,1,2 Yan Li,1 Zhi-yong Qian,1 Xiang Gao,1 Hua-shan Shi1,2 1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medicine School, Sichuan University, Chengdu, Sichuan, 2State Key Laboratory of Biotherapy and Department of Head and Neck Oncology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, 3Sichuang Haoyisheng Pharmacy, Chengdu, People’s Republic of China *These authors contributed equally to this work Abstract: Systemic administration of chemotherapy for cancer often has toxic side effects, limiting the doses that can be used in its treatment. In this study, we developed methoxy poly(ethylene glycol-poly(caprolactone (MPEG-PCL micelles loaded with curcumin and doxorubicin (Cur-Dox/MPEG-PCL that were tolerated by recipient mice and had enhanced antitumor effects and fewer side effects. It was shown that these Cur-Dox/MPEG-PCL micelles could release curcumin and doxorubicin slowly in vitro. The long circulation time of MPEG-PCL micelles and the slow rate of release of curcumin and doxorubicin in vivo may help to maintain plasma concentrations of active drug. We also demonstrated that Cur-Dox/MPEG-PCL had improved antitumor effects both in vivo and in vitro. The mechanism by which Cur-Dox/MPEG-PCL micelles inhibit lung cancer might involve increased apoptosis of tumor cells and inhibition of tumor angiogenesis. We found advantages using Cur-Dox/MPEG-PCL micelles in the treatment of cancer, with Cur-Dox/MPEG-PCL achieving better inhibition of LL/2 lung cancer growth in vivo and in vitro. Our study indicates that Cur-Dox/MPEG-PCL micelles may be an effective treatment strategy for cancer in the future. Keywords: methoxy poly(ethylene glycol, poly(caprolactone, curcumin, doxorubicin, micelles, cancer, treatment

  18. A functional SNP upstream of the ADRB2 gene is associated with COPD

    Directory of Open Access Journals (Sweden)

    Li JX

    2018-03-01

    Full Text Available Jin-Xiu Li,1,2,* Wei-Ping Fu,3,* Jing Zhang,4 Xiao-Hua Zhang,1,2 Chang Sun,1,5 Lu-Ming Dai,3 Li Zhong,1,5,6 Li Yu,1,2 Ya-Ping Zhang1,7 1State Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan, 2Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, School of Life Sciences, Yunnan University, 3Department of Respiratory Critical Care Medicine, 4Department of Thoracic Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, 5College of Life Sciences, 6Provincial Demonstration Center for Experimental Biology Education, Shaanxi Normal University, Xi’an, 7State Key Laboratory of Genetic Resources and Evolution, and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China *These authors contributed equally to this work Background: Previous studies have suggested that β2-adrenergic receptor (ADRB2 is associated with COPD. However, the role of genetic polymorphisms in ADRB2 on COPD has not been evaluated yet. Methods: In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-time polymerase chain reaction were adopted to investigate the association between ADRB2 genetic polymorphisms and COPD, comprehensively. Results: One single nucleotide polymorphism (rs12654778, located upstream of ADRB2, showed a significant association with COPD by the logistic regression analysis after adjusting for age, sex and smoking history (p=0.04 in 200 COPD patients and 222 controls from southwest Chinese population. Furthermore, the luciferase assay indicated that rs12654778-A allele reduced the relative promoter activity by ~26% compared with rs12654778-G allele (p=0.0034. The chromatin immunoprecipitation analysis demonstrated that rs12654778 modulated the binding affinity of transcription factor neurofibromin 1. In addition, a significantly reduced expression of ADRB

  19. Overexpression of ETV4 protein in triple-negative breast cancer is associated with a higher risk of distant metastasis

    Directory of Open Access Journals (Sweden)

    Yuan ZY

    2014-09-01

    Full Text Available Zhong-Yu Yuan,1–3,* Ting Dai,1,2,* Shu-Sen Wang,1–3 Rou-Jun Peng,1–3 Xing-Hua Li,1,2 Tao Qin,1–3 Li-Bing Song,1,2 Xi Wang1,2,41State Key Laboratory of Oncology in South China, Guangzhou, People's Republic of China; 2Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China; 3Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China; 4Department of Breast Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China  *These authors contributed equally to this work Background: Patients with triple-negative breast cancer (TNBC present a higher probability of distant metastasis and lack of effective targeted therapy. ETS translocation variant 4 (ETV4 is an ETS (E-26 transcription factor and has been associated with tumor metastasis. However, the clinical and functional significance of ETV4 in TNBC still remains unclear. Methods: A human tumor metastasis polymerase chain reaction array was used to profile differential expression of tumor metastasis-related genes in TNBC tissue. Real-time reverse transcription and Western blot analyses were performed to verify ETV4 expression in TNBC cells and tissue. Immunohistochemistry was used to detect expression of ETV4 protein in 135 TNBC tissue samples for association between ETV4 protein expression and clinical outcomes. Results: A total total of eight upregulated (CCL7, KISS1, MET, MMP7, NR4A3, ETV4, TIMP3, and TSHR and three downregulated (ITGA7, SSTR, and MMP2 genes were identified between TNBC tissue and the luminal subtype of breast cancer tissue. ETV4 messenger ribonucleic acid was more than five-fold upregulated in TNBC tissue compared with the control tissue. ETV4 overexpression was found in 57.0% of 135 TNBC cases. Overexpression of ETV4 protein was associated with an advanced stage and a higher proportion of positive lymph node and lymphovascular invasion. Patients with an ETV4

  20. Using the geometric mean fluorescence intensity index method to measure ZAP-70 expression in patients with chronic lymphocytic leukemia

    Directory of Open Access Journals (Sweden)

    Wu YJ

    2016-02-01

    Full Text Available Yu-Jie Wu, Hui Wang, Jian-Hua Liang, Yi Miao, Lu Liu, Hai-Rong Qiu, Chun Qiao, Rong Wang, Jian-Yong Li Department of Hematology, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, People’s Republic of China Abstract: Expression of ζ-chain-associated protein kinase 70 kDa (ZAP-70 in chronic lymphocytic leukemia (CLL is associated with more aggressive disease and can help differentiate CLL from cases expressing mutated or unmutated immunoglobulin heavy chain variable region (IgHV genes. However, standardizing ZAP-70 expression by flow cytometric analysis has proved unsatisfactory. The key point is that ZAP-70 is weakly expressed with a continuous expression pattern rather than a clear discrimination between positive and negative CLL cells, which means that the resulting judgment is subjective. Thus, in this study, we aimed at assessing the reliability and repeatability of ZAP-70 expression using the geometric mean fluorescence intensity (geo MFI index method based on flow cytometry with 256-channel resolution in a series of 402 CLL patients and to compare ZAP-70 with other biological and clinical prognosticators. According to IgHV mutational status, we were able to confirm that the optimal cut-off point for the geo MFI index was 3.5 in the test set. In multivariate analyses that included the major clinical and biological prognostic markers for CLL, the prognostic impact of ZAP-70 expression appeared to have stronger discriminatory power when the geo MFI index method was applied. In addition, we found that ZAP-70-positive patients according to the geo MFI index method had shorter time to first treatment or overall survival (P=0.0002, P=0.0491. This is the first report showing that ZAP-70 expression can be evaluated by a new approach, the geo MFI index, which could be a useful prognostic method as it is more reliable, less subjective, and therefore better associated with improvement of CLL prognostication

  1. Biosynthesis of gold nanoparticles by the extreme bacterium Deinococcus radiodurans and an evaluation of their antibacterial properties

    Directory of Open Access Journals (Sweden)

    Li J

    2016-11-01

    Full Text Available Jiulong Li,1,* Qinghao Li,1,* Xiaoqiong Ma,2,* Bing Tian,1 Tao Li,1 Jiangliu Yu,1 Shang Dai,1 Yulan Weng,1 Yuejin Hua1 1Key Laboratory for Nuclear-Agricultural Sciences of Chinese Ministry of Agriculture and Zhejiang Province, Institute of Nuclear-Agricultural Sciences, Zhejiang University, 2Central Laboratory, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China *These authors contributed equally to this work Abstract: Deinococcus radiodurans is an extreme bacterium known for its high resistance to stresses including radiation and oxidants. The ability of D. radiodurans to reduce Au(III and biosynthesize gold nanoparticles (AuNPs was investigated in aqueous solution by ultraviolet and visible (UV/Vis absorption spectroscopy, electron microscopy, X-ray diffraction (XRD, dynamic light scattering (DLS, Fourier transform infrared spectroscopy (FTIR and X-ray photoelectron spectroscopy (XPS. D. radiodurans efficiently synthesized AuNPs from 1 mM Au(III solution in 8 h. The AuNPs were of spherical, triangular and irregular shapes with an average size of 43.75 nm and a polydispersity index of 0.23 as measured by DLS. AuNPs were distributed in the cell envelope, across the cytosol and in the extracellular space. XRD analysis confirmed the crystallite nature of the AuNPs from the cell supernatant. Data from the FTIR and XPS showed that upon binding to proteins or compounds through interactions with carboxyl, amine, phospho and hydroxyl groups, Au(III may be reduced to Au(I, and further reduced to Au(0 with the capping groups to stabilize the AuNPs. Biosynthesis of AuNPs was optimized with respect to the initial concentration of gold salt, bacterial growth period, solution pH and temperature. The purified AuNPs exhibited significant antibacterial activity against both Gram-negative (Escherichia coli and Gram-positive (Staphylococcus aureus bacteria by damaging their cytoplasmic membrane. Therefore, the extreme

  2. Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor

    Directory of Open Access Journals (Sweden)

    Wang G

    2018-04-01

    Full Text Available Guang-Yu Wang,1,* Ling Li,2,* Bo Liu,1 Xiao Han,1 Chun-Hua Wang,1 Ji-Wen Wang3 1Department of Neurosurgery, 2Department of Pediatrics, Qilu Children’s Hospital of Shandong University, Jinan, Shandong, 3Department of Neurology, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Pudong New District, Shanghai, People’s Republic of China *These authors contributed equally to this work Purpose: This study aimed to explore significant genes and pathways involved in the pathogenesis of supratentorial primitive neuroectodermal tumor (sPNET. Materials and methods: Gene expression profile of GSE14295 was downloaded from publicly available Gene Expression Omnibus (GEO database. Differentially expressed genes (DEGs were screened out in primary sPNET samples compared with normal fetal and adult brain reference samples (sPNET vs fetal brain and sPNET vs adult brain. Pathway enrichment analysis of these DEGs was conducted, followed by protein–protein interaction (PPI network construction and significant module selection. Additionally, transcription factors (TFs regulating the common DEGs in the two comparison groups were identified, and the regulatory network was constructed. Results: In total, 526 DEGs (99 up- and 427 downregulated in sPNET vs fetal brain and 815 DEGs (200 up- and 615 downregulated in sPNET vs adult brain were identified. DEGs in sPNET vs fetal brain and sPNET vs adult brain were associated with calcium signaling pathway, cell cycle, and p53 signaling pathway. CDK1, CDC20, BUB1B, and BUB1 were hub nodes in the PPI networks of DEGs in sPNET vs fetal brain and sPNET vs adult brain. Significant modules were extracted from the PPI networks. In addition, 64 upregulated and 200 downregulated overlapping DEGs were identified in both sPNET vs fetal brain and sPNET vs adult brain. The genes involved in the regulatory network upon overlapping DEGs and the TFs were correlated with calcium signaling pathway

  3. Enhanced immunization via dissolving microneedle array-based delivery system incorporating subunit vaccine and saponin adjuvant

    Directory of Open Access Journals (Sweden)

    Zhao JH

    2017-07-01

    Full Text Available Ji-Hui Zhao,1,* Qi-Bo Zhang,1,* Bao Liu,2 Xiang-Hua Piao,1 Yu-Lu Yan,1 Xiao-Ge Hu,1 Kuan Zhou,1 Yong-Tai Zhang,1 Nian-Ping Feng1 1School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Anethesiology Department, Augusta University, Augusta, GA, USA *These authors contributed equally to this work Purpose: To enhance the immunogenicity of the model subunit vaccine, ovalbumin (OVA was combined with platycodin (PD, a saponin adjuvant. To reduce the toxicity of PD, OVA, and adjuvant were loaded together into liposomes before being incorporated into a dissolving microneedle array.Methods: OVA- and PD-loaded liposomes (OVA-PD-Lipos were prepared using the film dispersion method. Their uptake behavior, toxicity to mouse bone marrow dendritic cells (BMDCs, and hemolytic activity to rabbit red blood cells (RBCs were evaluated. The OVA-PD-Lipos were incorporated into a dissolving microneedle array. The chemical stability of OVA and the physical stability of OVA-PD-Lipos in microneedle arrays were investigated. The immune response of Institute of Cancer Research mice and potential skin irritation reaction of rabbits to OVA-PD-Lipos-MNs were evaluated.Results: The uptake of OVA by mouse BMDCs was greatly enhanced when OVA was prepared as OVA-PD-Lipos, and in this form, the toxicity of PD was dramatically reduced. OVA was chemically stable as OVA-PD-Lipos, when OVA-PD-Lipos was incorporated into a dissolving microneedle array. Institute of Cancer Research mice treated with OVA-PD-Lipos-MNs showed a significantly enhanced immune response. PD combined with OVA elicited a balanced Th1 and Th2 humoral immune response in mice, with minimal irritation in rabbit skin.Conclusion: The dissolving microneedle array-based system is a promising delivery vehicle for subunit vaccine and its adjuvant. Keywords: subunit vaccine, saponin adjuvant, liposomes, dissolving microneedle array, intradermal vaccination

  4. Enrichment of CD44 in basal-type breast cancer correlates with EMT, cancer stem cell gene profile, and prognosis

    Directory of Open Access Journals (Sweden)

    Xu HX

    2016-01-01

    Full Text Available Hanxiao Xu,1 Yijun Tian,1 Xun Yuan,1 Yu Liu,2 Hua Wu,1 Qian Liu,1 Gen Sheng Wu,3,4 Kongming Wu1 1Department of Oncology, 2Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 3Department of Oncology, 4Department of Pathology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA Abstract: Cluster of differentiation 44 (CD44 is a transmembrane glycoprotein that serves as the receptor for the extracellular matrix component hyaluronic acid. CD44 has been reported to play key roles in cell proliferation, motility, and survival, but its role in breast cancer remains controversial. In this study, we conducted a meta-analysis. A total of 23 published Gene Expression Omnibus databases were included to evaluate the association between CD44 mRNA expression and clinicopathological characteristics or prognosis of the patients with breast cancer. Our analysis revealed that CD44 expression was associated with clinicopathological features, including the histological grade, estrogen receptor status, progesterone receptor status, and human epidermal growth factor receptor-2 status. Higher levels of CD44 expression were observed in the basal subtype of breast cancer both at the mRNA and protein levels (odds ratio [OR] =2.08, 95% confidence interval [CI]: 1.72–2.52; OR =2.11, 95% CI: 1.67–2.68. Patients with CD44 overexpression exhibited significantly worse overall survival (hazard ratio =1.27; 95% CI: 1.04–1.55. Whole gene profile analysis revealed that CD44 expression was enriched in basal-type breast cancer and correlated with epithelial–mesenchymal transition and cancer stem cell gene profiles. In summary, our analyses indicated that CD44 potentially might be a prognostic marker for breast cancer and thus can serve as a therapeutic target for basal-type breast cancer. Keywords: breast cancer, CD44, survival prediction, meta

  5. Intracellular disposition of chitosan nanoparticles in macrophages: intracellular uptake, exocytosis, and intercellular transport

    Directory of Open Access Journals (Sweden)

    Jiang LQ

    2017-08-01

    Full Text Available Li Qun Jiang,1 Ting Yu Wang,1 Thomas J Webster,2 Hua-Jian Duan,1 Jing Ying Qiu,1 Zi Ming Zhao,1 Xiao Xing Yin,1,* Chun Li Zheng3,* 1Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, People’s Republic of China; 2Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 3School of Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China *These authors contributed equally to this work Abstract: Biodegradable nanomaterials have been widely used in numerous medical fields. To further improve such efforts, this study focused on the intracellular disposition of chitosan nanoparticles (CsNPs in macrophages, a primary cell of the mononuclear phagocyte system (MPS. Such interactions with the MPS determine the nanoparticle retention time in the body and consequently play a significant role in their own clinical safety. In this study, various dye-labeled CsNPs (about 250 nm were prepared, and a murine macrophage cell line (RAW 264.7 was selected as a model macrophage. The results showed two mechanisms of macrophage incorporation of CsNPs, ie, a clathrin-mediated endocytosis pathway (the primary and phagocytosis. Following internalization, the particles partly dissociated in the cells, indicating cellular digestion of the nanoparticles. It was proved that, after intracellular uptake, a large proportion of CsNPs were exocytosed within 24 h; this excretion induced a decrease in fluorescence intensity in cells by 69%, with the remaining particles possessing difficulty being cleared. Exocytosis could be inhibited by both wortmannin and vacuolin-1, indicating that CsNP uptake was mediated by lysosomal and multivesicular body pathways, and after exocytosis, the reuptake of CsNPs by neighboring cells was verified by further experiments. This study, thus, elucidated the fate of CsNPs in macrophages as well as identified cellular disposition

  6. Catalytic Oxidation by Transition Metal Ions in Zeolites.

    Science.gov (United States)

    1984-09-28

    exotic schemes were developed. It was previously demonstrated that MoCI5 may be reacted with a HYu (here Yu denotes a steam-stabilized or...34ultrastable" zeolite) to form a MoYu zeolite and HC1 which is removed from the system.1 In this study, MoYu zeolites have been prepared by reacting HYu with Mo

  7. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Properties of ternary NiFeW alloy coating by jet electrodeposition · J K YU J ZHAO M Q YU ... Article ID 43. Effects of static electricity and fabrication parameters on PVDF film properties ..... PING YANG JUN HU YOUCHUN YU BIN WANG ... Studies of thermally assisted interactions of polysulphide polymer with ionic liquids.

  8. What to Build for Middle-Agers to Come? Attractive and Necessary Functions of Exercise-Promotion Mobile Phone Apps: A Cross-Sectional Study.

    Science.gov (United States)

    Liao, Gen-Yih; Chien, Yu-Tai; Chen, Yu-Jen; Hsiung, Hsiao-Fang; Chen, Hsiao-Jung; Hsieh, Meng-Hua; Wu, Wen-Jie

    2017-05-25

    with 14 design features, medium level with 6 features, whereas low-level participants are recommended with 1 feature. The analysis suggests that the implementation of demanded features could be low, as the average prevalence of demanded design features is 20% (4.3/21). Surprisingly, social comparison and social support, most implemented features in current apps, were categorized into the indifferent category. The magnitude of effect is larger for MPSE because it effects quality perception of more design features than PA. Delving into the 52 regression models revealed that high MPSE more likely induces attractive or one- dimensional categorization, suggesting the importance of technological self-efficacy on eHealth care promotion. This study is the first to propose middle-agers' needs in relation to mobile phone exercise-promotion. In addition to the tailor-made recommendations, suggestions are offered to app designers to enhance the performance of persuasive features. An interesting finding on change of quality perception attributed to MPSE is proposed as future research. ©Gen-Yih Liao, Yu-Tai Chien, Yu-Jen Chen, Hsiao-Fang Hsiung, Hsiao-Jung Chen, Meng-Hua Hsieh, Wen-Jie Wu. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 25.05.2017.

  9. Increased matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio in smokers with airway hyperresponsiveness and accelerated lung function decline

    Directory of Open Access Journals (Sweden)

    Lo CY

    2018-04-01

    Full Text Available Chun-Yu Lo,1 Hung-Yu Huang,1 Jung-Ru He,1 Tzu-Ting Huang,1 Chih-Chen Heh,1 Te-Fang Sheng,1 Kian Fan Chung,2 Han-Pin Kuo,1 Chun-Hua Wang1 1Department of Thoracic Medicine, Chang Gung Medical Foundation, College of Medicine, Chang Gung University, Taipei, Taiwan; 2Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK Background: Airway hyperresponsiveness (AHR is associated with airway inflammation and a rapid decline in lung function and is a predictor of future risk of COPD among smokers. Alveolar macrophages (AMs from patients with COPD release a greater amount of matrix metalloproteinase (MMP-9. We hypothesized that the imbalance between MMP-9 and tissue inhibitor of metalloproteinase-1 (TIMP-1 is related to AHR in smokers.Patients and methods: Healthy smokers with AHR (AHR + S or smokers without AHR (AHR - S; divided according to a methacholine challenge test and nonsmokers without AHR (AHR - NS were enrolled. Spirometry was performed during enrollment and repeated after 5 years. Initially, AMs recovered from bronchoalveolar lavage (BAL fluid were cultured in the presence of p38 mitogen-activated protein kinase (MAPK inhibitor (SB203580, MAPK kinase (MEK 1/2 (the MEK of extracellular signal-regulated kinase [ERK] inhibitor, PD98059, or medium alone for 24 h. The release of MMP-9 and TIMP-1 in culture supernatants was measured by enzyme-linked immunosorbent assay.Results: A greater reduction in forced expiratory volume in 1 s (FEV1/forced vital capacity (FVC, FEV1 (as a percentage of the predicted value [%pred], and maximal mid-expiratory flow (MMEF was observed among AHR + S in the 5-year period. There was a higher proportion of neutrophils and a lower proportion of AMs in BAL fluid recovered from AHR + S. Compared to AMs from AHR - NS and AHR - S, AMs from nonsmokers with AHR (AHR + NS released more MMP-9 and less TIMP-1, with an increase in MMP-9/TIMP-1 ratios. The MMP-9/TIMP-1 ratio in smokers

  10. Comparison of the clinical features and outcomes in two age-groups of elderly patients with atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Shao XH

    2014-08-01

    Full Text Available Xing-Hui Shao,1 Yan-Min Yang,1 Jun Zhu,1 Han Zhang,1 Yao Liu,1 Xin Gao,1 Li-Tian Yu,1 Li-Sheng Liu,1 Li Zhao,2 Peng-Fei Yu,3 Hua Zhang,4 Qing He,5 Xiao-Dan Gu6 1Emergency and Intensive Care Center, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 2Department of Emergency, Fu Xing Hospital, Capital Medical University, Beijing, 3Department of Cardiology, Pingdu People’s Hospital, Pingdu, 4Department of Emergency, Qingdao Municipal Hospital, Qingdao, 5Department of Emergency, West China Hospital, Sichuan University, Chengdu, 6Department of Emergency, Sixth People’s Hospital of Chengdu, Chengdu, People’s Republic of China Background: Atrial fibrillation (AF disproportionately affects older adults. However, direct comparison of clinical features, medical therapy, and outcomes in AF patients aged 65–74 and ≥75 years is rare. The objective of the present study was to evaluate the differences in clinical characteristics and prognosis in these two age-groups of geriatric patients with AF.Materials and methods: A total of 1,336 individuals aged ≥65 years from a Chinese AF registry were assessed in the present study: 570 were in the 65- to 74-year group, and 766 were in the ≥75-year group. Multivariable Cox hazards regression was performed to analyze the major adverse cardiac events (MACEs between groups.Results: In our population, the older group were more likely to have coronary artery disease, hypertension, previous stroke, cognitive disorder, or chronic obstructive pulmonary disease, and the 65- to 74-year group were more likely to have valvular heart disease, left ventricular systolic dysfunction, or sleep apnea. The older patients had 1.2-fold higher mean CHADS2 (congestive heart failure, hypertension, age ≥75 years, diabetes, stroke scores, but less ­probability of being prescribed drugs. Compared with those aged 65–74 years, the older group had a higher risk of death (hazard ratio 2

  11. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Li Wei1 2 Cheng Pengfei2 Bei Jinzhong2 Wen Hanjiang2 Wang Hua1 2. School of Geodesy and Geomatics, Wuhan University, Wuhan 430 079, China. Chinese Academic of Surveying and Mapping, Beijing 100 830, China.

  12. Diamond lemma for the group graded quasi-algebras

    Indian Academy of Sciences (India)

    Author Affiliations. MAMTA BALODI1 HUA-LIN HUANG2 SHIV DATT KUMAR1. Department of Mathematics, Motilal Nehru National Institute of Technology, Allahabad 211 004, India; School of Mathematics, Shandong University, Jinan 250100, China ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2007-06-28

    Jun 28, 2007 ... Author Affiliations. Jon D Wright1 Carmay Lim1 2. Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan, ROC; Department of Chemistry, National Tsing Hua University, Hsinchu 300, Taiwan, ROC ...

  14. Watershed Boundaries - WATERSHEDS_HUC06_USGS_IN: 6-Digit Accounting Units, Hydrologic Units, in Indiana, (Derived from US Geological Survey, 1:24,000 Polygon Shapefile)

    Data.gov (United States)

    NSGIC State | GIS Inventory — WATERSHEDS_HUC06_USGS_IN is a polygon shapefile showing the boundaries of accounting units (HUA) in Indiana. Accounting units are noted by a 6-digit hydrologic unit....

  15. Genomewide survey and characterization of metacaspase gene ...

    Indian Academy of Sciences (India)

    Oryza sativa). Likai Wang and Hua .... IND. Bangladesh. Ta Hung Ku. 1107_TEJ. TEJ. China. Darmali. 27630_TEJ. TEJ. Nepal. Phudugey. 32399_TEJ. TEJ. Bhutan. Haginomae Mochi. 2540_TEJ. TEJ. Japan. Norin 20. 418_TEJ. TEJ. Japan.

  16. Interleukin-6 but not soluble adhesion molecules has short-term ...

    African Journals Online (AJOL)

    Interleukin-6 but not soluble adhesion molecules has short-term prognostic value on mortality in patients with acute ST-segment elevation myocardial infarction. ZX Fan, Q Hua, J Tan, J Gao, RK Liu, Z Yang ...

  17. Dynamic QTL and epistasis analysis on seedling root traits in upland ...

    Indian Academy of Sciences (India)

    2014-04-21

    Apr 21, 2014 ... phenotypic values at the time t conditional on the pheno- typic values ...... root, which directly determines drought tolerance and yield potential of ..... Talents of the Ministry of Education (NCET-06-0106) to J. Hua. References.

  18. PREFACE: 14th International Conference on Metrology and Properties of Engineering Surfaces (Met & Props 2013)

    Science.gov (United States)

    Fu, Wei-En

    2014-03-01

    of Japan, Japan) Dr Heui-Jae Pahk (SNU Precision Co. Ltd., Korea) Professor Jiu-Bin Tan (Harbin Institute of Technology, China) Ms. Siew-Leng Tan (National Metrology Centre (NMC/A*STAR), Singapore) Mr. A. Tonmueanwai (National Institute of Metrology, Thailand (NIMT), Thailand) Professor Kazuhisa Yanagi (Nagaoka University, Japan) Local Organizing Committee Dr Victor Tzeng-Yow Lin (Center for Measurement Standards, ITRI, Taiwan) Professor Kuang-Chao Fan (National Taiwan University, Taiwan) Professor Jen-Fin Lin (ASME Fellow, National Cheng Kung University, Taiwan) Professor Chao-Chang Chen(National Taiwan University of Science and Technology, Taiwan) Professor Shih-Chieh Lin (National Tsing Hua University, Taiwan) Professor Liang-Chia Chen (National Taiwan University, Taiwan) Professor Fang-Jung Shiou (National Taiwan University of Science and Technology, Taiwan) Professor Chun-Hui Chung (National Taiwan University of Science and Technology, Taiwan) Professor Pin-Chuan Chen (National Taiwan University of Science and Technology, Taiwan) Dr Wen-En Fu (Center for Measurement Standards, ITRI, Taiwan)

  19. Optimizing Growth Conditions for Digoxin Production in Digitalis lanata Ehrh

    Directory of Open Access Journals (Sweden)

    Herman A. van Wietmarschen

    2016-08-01

    Full Text Available Objective: Digoxin is a therapeutic cardenolide widely used to treat various heart conditions such as atrial flutter, atrial fibrillation and heart failure in both Western as well as Chinese medicine. Digoxin is extracted from cultivated Digitalis lanata Ehrh. plants, known as Mao Hua Yang Di Huang in Chinese medicine. This manuscript presents two studies that were conducted to optimize the cultivation conditions for digoxin production in the TCM Mao Hua Yan Di Huang in a greenhouse under GAP conditions.

  20. Compilation of Abstracts of Dissertations, Theses, and Research Papers Submitted by Candidates for Degrees.

    Science.gov (United States)

    1979-09-30

    used by the subjects to rate the jobs: traditional masculine /feminine occupations, and the degree to which a job was or was not physically demanding...translations of Hua’s speeches and writ- ings. Findings: 1. Hua views the international system as conflictual and protracted. Superpower hegemony is the...from Lenin to Brezhnev, has consistently followed a pattern of developing a regional strategy to achieve hegemony in a given region, the latest example

  1. Clinical Application of Nape Acupuncture

    Institute of Scientific and Technical Information of China (English)

    HUA Xiao-yin; CUI Yi-jun

    2003-01-01

    @@ Nape Acupuncture refers to an acupuncture method at nuchal region. It was initiated and applied in clinic by Dr. HUA Yan-ling from Shanghai Research Institute of Acupuncture and Meridian and it can be used for treating diseases of nervous, circulatory and motor systems. Especially, it is more effective for brain-origin diseases. The author ever studied this acupuncture method from Dr. Hua and found it was effective according to clinical application. Now several typical cases are reported as follows.

  2. JPRS Report, Near East & South Asia

    Science.gov (United States)

    1988-01-20

    tracts with the private sector to take charge of their management. That is what actually happened in the sector of hotels and some tourist ... competition from these new countries in view of the similarity of their products. It also spoke about the negotiations which are underway now between the...Minister Indira Gandhi met Premier Hua Guofeng in Belgrade and during the Cancun con- ference in Mexico. Foreign Minister Huang Hua visited New

  3. Relationship between blood uric and acute cerebral infarction

    International Nuclear Information System (INIS)

    Yin Zhanxia; Zhao Danyang

    2011-01-01

    Objective: To study the relationship between blood uric acid and acute cerebral infarction. Methods: The level of blood uric acid and prevalence of hyperuricemia (HUA) were compared in 360 patients with acute cerebral infarction and 300 patients without it. According to the level of blood uric acid, 360 acute cerebral infarction patients were divided into HUA and normouricemia (NUA) groups. Age, sex, body mass index (BMI), blood glucose and total cholesterol were compared between the HUA and NUA group. The degree of neurological functional defection was compared between the two groups when patients were attacked by acute cerebral infarction. After a recovery treatment, the neurological functional defection of the two groups was compared a second time. Results: (1)The average blood uric acid level and prevalence of HUA were higher in patients with acute cerebral infarction. (2) The BMI, blood glucose and total cholesterol were higher in HUA group than in NUA group. (3) The neurological functional defection was more serious in HUA group when patients were attacked by acute cerebral infarction and after a recovery treatment. Conclusion: Hyperuricemia is related to acute cerebral infarction. (authors)

  4. Report on the survey of the project on the environmentally friendly type energy community field test. Investigative project for development and commercialization of recycle technology of waste edible oil; 2001 nendo kankyo chowa gata energy community field test jigyo chosa hokokusho. Hai shokuryo yu no recycle gijutsu kaihatsu to jitsuyoka no tameno chosa jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-06-01

    An investigative study was made of the use of waste edible oil as fuel and recycle use of residual food in the food service business. As to the existence/recovery of edible oil, it was found out that waste edible oil of 15.9g/meal per capita was discharged at multiple wide-area distributed shops and that the total amount reached 1,861kl/y in the country. Concerning the technology for using it as biodiesel fuel, Ronford Co., which has the most actual results of the technology, recovers waste edible oil in Kyoto City, refines it and uses it as fuel for the City's garbage truck. About the use of waste edible oil as boiler use fuel, there are examples in Sapporo Grand Hotel, which has been contributing to energy conservation for more than five years. In the assessment of the profitability as project, for the direct combustion for boiler fuel use, the same/large heat supply system is a prerequisite, and for the hot stove loaded type direct combustion, there is an element of the technology development. Therefore, the use as bio-diesel fuel is most expected, though there is a taxation problem. (NEDO)

  5. Ultrasonic Inspection following Heat Treatment of Uranium Alloys; Controle des Traitements Thermiques d'Alliage d'Uranium par Ultrasons; Kontrol' termicheskoj obrabotki uranovykh splavov s pomoshch'yu ul'trazvuka; Control Ultrasonico de los Tratamientos Termicos de Aleaciones de Uranio

    Energy Technology Data Exchange (ETDEWEB)

    Destribats, Marie-Therese; Cherpentier, C.; Papezik, F.; Pigeon, M. [Centre d' Etudes Nucleaires Desaclay (France)

    1965-10-15

    To improve the behaviour of low uranium alloys in reactors it is often necessary to reduce grain size by heat treatment. It has proved essential to provide for inspection of the whole element and the entire output in order to discover the exact quality of the fuel used. This inspection cannot be made by micrography because of the time required and the fact that the data obtained are incomplete. The inspection system adopted is based on the principle of absorption of ultrasonic waves by materials. This absorption depends on the structure of the medium. If {lambda} is small in relation to grain size G, absorption is low; whereas if G is of the order of {lambda}/2, absorption is very high. The tests were made first in air, using the multiple-echo system, then by measuring the height of the first echo, and finally by transmission in water, the height of the transmitted echo being compared with that of the initial signal. In industrial use, the amplitude of the echo transmitted by the material is compared with the echo obtained from a standard of the same characteristics and shape. Inspection takes place in a special machine in which the materials are rotated by rollers and adjustable transducers move over the element. The helicoidal scanning is carried out with a pitch of less than 5 mm. The ultrasonic generator includes a control system ensuring a constant reference echo. The paper quotes a series of records showing the results obtained with various alloys and in particular the faults observed in elements treated by induction upon linear displacement. The arrangement can detect faulty treatment zones of less than 1 cm{sup 2}. The system is at present used to inspect all low alloy uranium fuels of the G2, EL3, EDF1, EDF2 and INCA reactors, i.e. rods and tubes with diameters between 20 and 95 mm. (author) [French] Afin d'obtenir une meilleure tenue des alliages d'uranium faiblement allies dans les reacteurs, un affinage du grain par traitements thermiques est souvent necessaire. Il s'est avere indispensable de pouvoir effectuer un controle sur l'ensemble de l'element et la totalite d'une production afin de connaitre exactement la qualite du combustible utilise. Ce controle ne pouvait etre envisage par micrographie en raison de la duree trop longue des operations et de leurs resultats partiels. Le controle auquel les auteurs ont procede est base sur le principe de l'absorption des ultrasons par les materiaux. L'absorption est fonction de la structure du milieu. Si {lambda} est petit par rapport a la taille du grain G, elle est faible; si G est de l'ordre de {lambda}/2, elle est tres grande. Les tout premiers essais ont ete faits dans l'air, par echos multiples, puis en mesurant la hauteur du premier echo, ensuite par transmission dans l'eau, en comparant la hauteur de l'echo transmis a celle de l'echo initial. Dans le controle industriel, on compare l'amplitude de l'echo transmis par le materiau a l'echo obtenu avec un etalon bien traite de meme nuance et de meme forme geometrique. L'examen se fait dans une machine speciale; les materiaux sont entraines en rotation par des galets et les traducteurs orientables se deplacent le long de l'element. L'exploration helicoiedale s'effectue avec un pas inferieur a 5 mm. Le generateur d'ultrasons comporte un systeme de regulation qui maintient l'echo de reference constant. On montrera, une serie d'enregistrements obtenus sur divers alliages, en particulier des defauts observes sur les elements traites par induction au defile. Des zones mal traitees inferieures a 1 cm{sup 2} sont detectees. Actuellement, on controle ainsi tous les combustibles en uranium faiblement allies des divers reacteurs G2, EL3, EDF1, EDF2 et INCA, c'est-a-dire des barres et tubes de diametre compris entre 20 et 95 mm. (author) [Spanish] Con el fin de aumentar en los reactores la estabilidad de las aleaciones con bajo contenido de uranio resulta a menudo necessario afinar el grano mediente tratamientos termicos. Para conocer ia calidad del combustible utilizado se considera indispensable controlar el conjunto del elemento y la totalidad de la produccion. Este control no puede realizarse por micrograffa debido al tiempo prolongado que esta requiere y a sus resultados de caracter parcial. El metodo de control adoptado se basa en el principio de la absorcion de ondas ultrasonicas por los distintos materiales. Dicha absorcion es funcion de la estructura del medio. Si {lambda} es pequena en comparacion col el tamano del grano G, la absorcion resultara debil mientras que si G es del orden de {lambda}/2, la absorcion sera muy considerable. Los primeros ensayos se efectuaron en aire, utilizando ecos multiples y midiendo la altura del primer eco; los siguientes se realizaron por transmision en agua, comparando la altura del eco transmitido con la del inicial. En el control industrial, se compara la amplitud del eco transmitido por el material con la del obtenido usando una probeta patron sometida al tratamiento correcto, de la misma composicion y de igual forma geometrica. La inspeccion se realiza en una maquina especial; los materiales se hacen girar mediante roldanas y los transductores orientables se desplazan a lo largo del elemento. La exploracion helicoidal se lleva a cabo con un paso inferior a 5 mm. El generador de ondas ultrasonicas comprende un sistema de regulacion que mantiene constante la intensidad del eco de referencia. Se presenta una serie de registros obtenidos con diversas aleaciones y, en particular, defectos observados en elementos tratados por induccion durante el avance lineal. Se detectan zonas de tratamiento deficiente, de area inferior a 1 cm{sup 2}. En la actualidad se controlan de esta manera todos los combustibles aleados de bajo contenido de uranio destinados a los reactors G2, EL3, EDF1, EDF2 e INCA, es decir, barras y tubos con diametros comprendidos entre 20 y 95 mm. (author) [Russian] Chtoby dobit'sja luchshego rezhima raboty reaktorov, v kotoryh ispol'zujutsja slegka legirovannye splavy urana, chasto voznikaet neobhodimost' izmel'chat' zerna termicheskoj obrabotkoj. Pri jetom okazalos' neobhodimym osushhestvljat' kontrol' za vsemi jelementami i za vsem proizvodstvom, chtoby tochno znat' kachestvo ispol'zovannogo topliva. Jetot kontrol' nevozmozhno osushhestvljat' cherez mikrografiju, tak kak on zanimaet mnogo vremeni i ne daet polnyh rezul'tatov. Kontrol prinjatyj v jadernom centre, osnovan na principe pogloshhenija ul'trazvukov materialami. Dannoe pogloshhenie svjazano so strukturoj sredy. Esli znachenie Xmalo po sravneniju s velichinoj zerna {lambda}, to pogloshhenie slaboe, a esli G sostavljaet porjadka {lambda}/2, to pogloshhenie ochen' sil'noe. Vse pervye opyty provodili v vozduhe na osnove analiza mnogokratnyh jeho i zatem izmerjali vysoty pervogo jeha. Dalee izmerenie provodili v vode. Pri jetom sravnivali vysoty propushhennogo i pervonachal'nogo jeha. Pri promyshlennom kontrole sravnivaetsja amplituda jeha, propushhennogo cherez material, s jehom, poluchennym na horosho obrabotannom jetalone togo zhe tipa i toj zhe geometricheskoj formy. Ispytanie provodili v special'noj ustanovke, kogda materialy zapuskali v rotaciju s pomoshh'ju rolikov, a napravljaemye preobrazovateli peremeshhali vdol' jelementa. Vintovoe skennirovanie osushhestvljali pri shage menee 5 mm. V ul'trazvukovom generatore imeetsja sistema regulirovanija,kotoraja podderzhivaet kontrol'noe jeho. Privoditsja serija zapisej po razlichnym splavam, i v chastnosti govoritsja o defektah, nabljudaemyh u jelementov, kotorye byli obrabotany indukciej vo vremja prohozhdenija. Obnaruzhivajutsja ploho obrabotannye uchastki razmerom menee 1 sm{sup 2} . V nastojashhee vremja podobnym obrazom osushhestvljaetsja kontrol' za vsemi tipami topliva v vide slegka legirovannyh uranovyh splavov, primenjaemyh v reaktorah G2 EL3,EF1 EdF2 i INCA, inymi slovami, kontrolirujutsja vse sterzhni i trubki s diametrom mezhdu 20 i 95 mm. (author)

  6. Diffusion Parameters of BeO by the Pulsed Neutron Method; Calcul des Parametres de Diffusion de BeO par la Methode des Neutrons Pulses; Opredelenie diffuzionnykh parametrov BeO s pomoshch'yu metoda impul'snykh nejtronov; Determinacion de los Parametros de Difusion en el BeO por el Metodo de los Neutrones Pulsados

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, B. V.; Nargundkar, V. R.; Subbarao, K. [Atomic Energy Establishment Trombay, Bombay (India)

    1965-08-15

    The use of the pulsed neutron method for the precise determination of the diffusion parameters of moderators is described. The diffusion parameters of BeO have been obtained by this method. The neutron bursts were produced from a cascade accelerator by pulsing the ion source and using the Be (d, n) reaction. The detector was an enriched boron trifluoride proportional counter. It is shown that by a proper choice of the counter position arid length, and the source position, most of the space harmonics can be eliminated. Any constant background can be accounted for in the calculation of the decay constant. Very large bucklings were not used to avoid time harmonics. Any remaining harmonic content was rendered ineffective by the use of adequate time delay. The decay constant of the fundamental mode of the thermal neutron population was determined for several bucklings. Conditions to be satisfied for an accurate determination of the diffusion cooling constant C are discussed. The following values are obtained for BeO: {lambda}{sub 0} = absorption constant = 156.02 {+-} 4.37 s{sup -1} D = diffusion coefficient = (1.3334 {+-} 0.0128) x 10{sup 5} cm{sup 2}/s C = diffusion cooling constant = (-4.8758 {+-} 0.5846) x 10{sup 5} cm{sup 4}/s. The effect of neglecting the contribution of the B{sup 6} term on the determination of the diffusion parameters was estimated and is shown to be considerable. The reason for the longstanding discrepancy between the values of C obtained for the same moderator by different workers is attributed to this. (author) [French] Les auteurs decrivent l'emploi de la methode des neutrons puises pour la determination precise des parametres de diffusion des ralentisseurs. Ils ont calculi ceux de la glucine par cette methode. Des deuterons puises au moyen d'un accelerateur a cascade produisaient les bouffees de neutrons par la reaction Be (d, n). Le detecteur etait constitue par un compteur proportionnel au BF{sub 3} enrichi. En choisissant convenablement la position et la longueur du compteur d'une part, la position de la source d'autre part, il est possible d'eliminer la plupart des harmoniques spatiaux. Il est egalement possible de tenir compte de n'importe quel bruit de fond constant pour le calcul de la constante de decroissance. Il faut eviter les laplaciens tres eleves afin de ne pas avoir d {sup h}armoniques du temps. Tous les harmoniques qui restent sont rendus inoperants par un retard en temps adequat. Les auteurs ont determine la constante de decroissance du mode fondamental de la population de neutrons thermiques pour plusieurs laplaciens. Ils discutent les conditions a remplir pour une determination exacte de la constante du refroidissement par diffusion C. Pour la glucine, ils ont obtenu les constantes suivantes: {lambda}{sub 0} (constante d'absorption) = 156, 02 {+-} 4, 37 s{sup -1}. D (coefficient dediffusion) = (1,3334 {+-} 0,0128) * 10{sup 5} cm{sup 2}/s, C (constante du refroidissement de diffusion) = (-4,8758 {+-} 0,5846) * 10{sup 5} cm{sup 4}/s. Les auteurs ont etudie le role que peut jouer, dans la determination des parametres de diffusion, le fait que la contribution du terme en B{sup 6} est neglige; ils montrent qu'il est considerable. Ce serait la probablement la cause des ecarts entre les valeurs de C obtenues pour un meme ralentisseur par differents chercheurs. (author) [Spanish] Los autores describen el empleo del metodo de los neutrones pulsados para determinar con precision los parametros de difusion en moderadores. Con ayuda de este metodo, han obtenido los parametros de difusion en el BeO. Las rafagas de neutrones se generaron mediante un acelerador en cascada pulsando la fuente ionica y empleando la reaccion Be (d, n). Como detector se utilizo un contador proporcional de BF{sub 3} enriquecido. Los autores demuestran que por seleccion adecuada de la posicion y longitud del contador y de la ubicacion de la fuente, pueden eliminarse la mayoria de los armonicos espaciales. En el calculo de la constante de decrecimiento, fue posible tener en cuenta toda actividad de fondo constante. Para evitar armonicos temporales se prescindio de los laplacianos de valor muy elevado. Se elimino el efecto de todo contenido armonico remanente mediante el empleo de un retardo adecuado. Se determino, para varios laplacianos, la constante de decrecimiento del modo fundamental de la poblacion de neutrones termicos. Los autores examinan las condiciones que han de satisfacerse para determinar con precision la constante C de enfriamiento por difusion. Los valores obtenidos para el BeO fueron los siguientes: {lambda}{sub 0} = constante de absorcion = 156, 02 {+-} 4,37 s{sup -1}, D = coeficiente de difusion = (1,3334 {+-} 0,0128) * 10{sup 5} cm{sup 2}/s, C = constante de enfriamiento por difusion = (-4,8758 {+-} 0,5846) * 10{sup 5} cm{sup 4}/s. Los autores calcularon el efecto de despreciar la influencia del termino B{sup 6} sobre la determinacion de los parametros de difusion, demostrando que es considerable. Atribuyen a ese efecto la persistente discrepancia entre los valores de C obtenido para el mismo moderador por distintos investigadores. (author) [Russian] Opisyvaetsja primenenie metoda impul'snyh nejtronov dlja toch- nogo opredelenija diffuzionnyh parametrov zamedlitelej. S pomoshh'ju jetogo metoda byli polucheny diffuzionnye parametry VeO. Impul'sy nejtronov poluchalis' s pomoshh'ju kas- kadnogo uskoritelja v rezul'tate pul'sirovanija istochnika ionov i ispol'zovanija reakcii Be (d, n). Detektorom sluzhil proporcional'nyj schetchik iz obogashhennogo grehftoristogo bora. Pokazano, chto pri pravil'nom vybore polozhenija i dliny schetchika, a takzhe polozhenija istochnika, mozhno ustranit' bol'shuju chast' prostranstvennyh garmonik. Ljuboj postojannyj fon mozhet byt' uchten pri raschete postojannoj raspada. Chtoby izbezhat' vremennyh garmo- nik, ochen' bol'shie laplasiany ne ispol'zovalis'. Vse ostavshiesja garmoniki byli svedeny na net blagodarja ispol'zovaniju pravil'nogo vremeni zapazdyvanija. Postojannaja raspada osnovnogo sostojanija plotnosti teplovyh nejtronov Oyla opredelena dlja neskol'kih lapla- sianov. Rassmatrivajutsja te uslovija, kotorye dolzhny byt' sobljudeny dlja tochnogo opre- delenija konstanty diffuzionnogo ohlazhdenija (S). Dlja VeO polucheny sledujushhie velichiny: {lambda}{sub 0} = postojannaja pogloshhenija = 156,02 {+-} 4,37 sek{sup -1}, D = kojefficient diffuzii = (1,3334 {+-} 0,0128) {+-} 10{sup 5} sm2/sek, S = postojannaja diffuzionnogo ohlazhdenija = (-4,8758 {+-} 0,5846) * 10{sup 5} sm{sup 4}/sek. Vyjavleny posledstvija prenebrezhenija V{sup 6} pri opredelenii diffuzionnyh parametrov, pokazano, chto jeti posledstvija javljajutsja znachitel'nymi i ob{sup j}asnjajut sushhestvovavshee v teche- nie dlitel'nogo vremeni rashozhdenie mezhdu znachenijami S, poluchennymi dlja odnogo i togo zhe zamedlitelja razlichnymi issledovateljami. (author)

  7. Diagnosis of Massive Pulmonary Embolism in Man by Radioisotope Scanning; Diagnostic par Scintigraphy de l'Embolie Pulmonaire Massive chez l'Homme; Diagnostika massivnoj legochnoj ehmbolii u cheloveka s pomoshch'yu radioizotopnogo skennirovaniya; Diagnostico de la Embolia Pulmonar Masiva en el Hombre por Exploracion Radioisotopica

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Jr., H. N.; Sabiston, Jr., D. C.; Iio, M.; Langan, J. K. [Departments of Medicine, Surgery and Radiology, Johns Hopkins University School of Medicine, Baltimore, MD (United States)

    1964-10-15

    Macroaggregated human-serum albumin particles labelled with either I{sup 131} or chromium-51 have been utilized to determine regional blood flow to the lungs in dogs and man. Following intravenous injection, the particles accumulated in the lung, permitting clear delineation of the lung fields by scintillation scanning. In patients with lung abscess, pneumonia, atelectasis, tumours and thromboembolic disease of the lung, there was a decreased accumulation of the radioactivity in the regions of the lungs involved. The technique was found to be clinically useful in the diagnosis of massive pulmonary emboli in man and in the demonstration of vascular occlusion in certain patients with cor pulmonale. Studies in dogs made possible the determination of the rate at which revascularization occurred following experimental pulmonary emboli. Scintillation scanning was carried out at various times after the removal of the experimental emboli. The circulation was restored through the lungs within a period of several weeks after the removal of chronic pulmonary emboli in dogs. Although aggregated human-serum albumin retained its antigenicity in rabbits, guinea pigs and dogs, extensive studies failed to reveal any antigenicity of the particles to man. Because of the rapid metabolism of the macroaggregated albumin particles, the radiation to the patient was well within permissible levels. The use of albumin of high specific activity permitted injections of small chemical quantities; consequently no cardiovascular effects, such as increases in pulmonary artery pressure, changes in electrocardiogram or respiratory rate, were noted. (author) [French] Pour determiner chez le chien et chez l'homme le flux sanguin vers les poumons, on a utilise des macroparticules d'albumine de serum humain marquee avec {sup 131}I ou {sup 51}Cr. A la suite d'une injection intraveineuse, les particules s'accumulaient dans les poumons, permettant ainsi de delimiter nettement les regions pulmonaires par scintigraphie. Chez les sujets atteints d'abces pulmonaires, de pneumonie, d'atelectasie, de tumeurs ou dethrombo- embolie des poumons, on observait une accumulation moins intense de la radioactivite dans les regions pulmonaires affectees. Du point de vue clinique, cette methode s'est revelee utile pour le diagnostic des embolies pulmonaires massives chez l'homme et pour la mise en evidence d'une occlusion vasculaire chez certains sujets atteints de coeur pulmonaire. Les etudes sur des chiens ont permis de determiner le rythme auquel une vascularisation nouvelle se produisait a la suite d'embolies pulmonaires induites. On a fait des scintigraphies a diverses reprises apres embolectomie. Chez les chiens, la circulation dans les poumons etait retablie dans les quelques semaines qui suivaient l'embolectomie. Si les macroparticules d'albumine de serum humain gardaient leur caractere antigene chez les lapins, les cobayes et les chiens, des etudes tres poussees n'ont pu deceler un tel caractere chez l'homme. Par suite du metabolisme rapide des macroparticules d'albumine, la dose de radioactivite recue par les sujets restait bien en deca des niveaux admissibles. L'emploi d'albumine a forte activite specifique permettait de faire des injections de petites quantites de produit chimique; de ce fait, on n'a pas releve d'effets cardio-vasculaires, tels que des augmentations de la tension dans l'artere pulmonaire, des modifications de l'electro-cardiogramme ou du rythme respiratoire, etc. (author) [Spanish] Los autores utilizaron macroagregados de particulas de seroalbumina humana marcada con {sup 131}I o con {sup 51}Cr para determinar el caudal sanguineo regional que afluye a los pulmones en el perro y en el hombre. Inyectadas por via intravenosa, las particulas se acumulan en el pulmon y permiten delinear claramente los campos pulmonares por exploracion centelleografica. En pacientes con absceso del pulmon, neumonia, atelectasia, tumores y tromboembolias pulmonares, se observo una acumulacion disminuida de radiactividad en las regiones afectadas. Se comprobo la utilidad clinica de esta tecnica para diagnosticar embolias pulmonares masivas en el hombre y para descubrir oclusiones vasculares en ciertos pacientes afectados de cor pulmonale. Los estudios en perros permitieron determinar la rapidez con que progresa la revascularizacion despues de una embolia pulmonar experimental. Se efectuaron varias exploraciones centelleograficas una vez retirados los embolos experimentales. La circulacion se restablecio en todo el pulmon algunas semanas despues de haber eliminado los embolos pulmonares cronicos en los perros. Los agregados de seroalbumina humana han conservado su poder antigenico en los conejos, los cobayos y los perros, pero los estudios realizados no han permitido comprobar que las particulas tengan poder antigenico alguno en el hombre. Gracias al rapido metabolismo de los macroagregados, la dosis de radiacion recibida por el paciente se mantiene bastante inferior a los valores admisibles. El empleo de albuminas de elevada actividad especifica permite limitar considerablemente las cantidades inyectadas; no se observan, por lo tanto, efectos cardiovasculares tales como aumentos de presion en la arteria pulmonar, ni alteraciones del electrocardiograma o del ritmo respiratorio. (author) [Russian] Krupnye chasticy al'bumina syvorotki cheloveka, mechennye jodom-131 ili hromom-51, ispol'zovalis' dlja opredelenija regional'nogo toka krovi v legkih u sobak i cheloveka. Posle vnutrivennogo vvedenija chasticy, nakaplivajushhiesja v legkih, dajut chetkoe izobrazhenie konturov legkih pri scintilljacionnom skenniro- vanii. U pacientov s legochnymi abscessami, pnevmoniej, atelektazom, rakom legkih i trombojembolicheskoj bolezn'ju legkih nabljudalos' ponizhenie nakoplenija radioaktivnosti v porazhennyh uchastkah. Byl najden metod, kotoryj budet prigoden v klinike dlja diagnostiki massivnoj legochnoj jembolii u cheloveka i demonstracii zakuporki sosudov u nekotoryh pacientov s ''cor pulmonale''. Issledovanija na sobakah sdelali vozmozhnym opredelenie skorosti revaskuljarizacii posle jeksperimental'noj legochnoj jembolii. Scintilljacionnoe skennirovanie provodilos' v razlichnye periody vremeni posle udalenija jeksperimental'nogo jembola. Cirkuljacija krovi v legkih u sobak vosstanavlivalas' v techenie neskol'kih nedel' posle udalenija hronicheskogo legochnogo jembola. Hotja krupnye chasticy al'bumina syvorotki cheloveka sohranjali svoi antigennye svojstva dlja krolikov, morskih svinok i sobak, shirokie issledovanija ne priveli k obnaruzheniju kakih-libo antigennyh svojstv jetih chastic dlja cheloveka. Vvidu bystrogo metabolizma krupnyh chastic al'bumina doza obluchenija pacienta nahodilas' v predelah dopustimyh doz. Ispol'zovanie al'bumina s vysokoj udel'noj aktivnost'ju pozvoljalo vvodit' nebol'shie himicheskie kolichestva; vposledstvii ne otmecheno kakih-libo izmenenij so storony serdechno-sosudistoj sistemy, kak povyshenija davlenija v legochnoj arterii, izmenenija jelektrokardiogrammy ili chastoty dyhanija.

  8. 面对文字的历史:仪式之"乐"与身体记忆%Another Kind of Memory: In Search of Alternative History Through the Meaning of Yue (Music) in Ritual ( miandui wenzi de iishi: yishi zhi "yue" yu shenti jiyi)

    Institute of Scientific and Technical Information of China (English)

    萧梅

    2006-01-01

    本文立足于民族音乐学实地考察之经验,以及相关领域的理论梳理,着重于任何仪式活动都不可或缺之"乐",探索其中存在的以人的身体的直接感受为媒介的记忆方式和"时间性"体现的可能,及其对于音乐学学科发展的意义.

  9. FY 1998 annual report on the research on the possibility of introducing a usable chemical substance manufacturing system by utilizing natural gas containing CO2; CO{sub 2} gan'yu tennen gas den katsuyo ni yoru yuyo kagaku busshitsu seizo system donyu kanosei ni kansuru chosa kenkyu 1998 nendo chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The trends of effective use of gas containing CO2 from natural gas fields are surveyed, and usable chemical substance manufacturing systems which utilize natural energy are investigated, evaluated and analyzed, to extract promising systems for effective use of CO2-containing natural gas and thereby to promote its effective use. Chapter 1 outlines possibility of integrated use of gas containing CO2 from natural gas fields and natural gas energy. Chapter 2 describes the research trends in the CO2 conversion reactions for using unexploited CO2 as the carbon source. Chapter 3 describes natural energy utilization technology applicable to gas containing CO2 from natural gas fields. Chapter 4 describes performance of chemical manufacturing systems utilizing natural gas containing CO2. The energy balances and CO2 emission coefficients are estimated, based on the above. The evaluation is implemented in the order of (1) conventional steam reforming, (2) steam reforming in which heat is supplied by a solar furnace, (3) examination of the exhaust gases from a methanol synthesis process, and (4) examination of CO2-mixed reforming. Chapter 5 describes summary and proposals. (NEDO)

  10. Achievement report for fiscal 1999. Joint verification research on use for power generation of Omani superhigh-viscosity crude oil remaining unexploited; 1999 nendo Oman koku ni okeru miriyo chokonensei gen'yu no denryoku riyo ni kansuru kyodo jissho kenkyu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A Mukhaizna oil field remains to be exploited in Oman, with an estimated reserve of 2.4-billion barrels of very heavy oil with an API (American Petroleum Institute) specific gravity of 15.3. The viscosity of the oil is so high as to be over 100-thousand cP (at 15 degrees C). The extremely high viscosity causes its exploitable rate to be so low as 3%, and makes shipment by pipeline quite difficult. In this survey, a method using water emulsion is proposed for viscosity reduction, which aims to reduce the Mukhaizna crude oil viscosity to 200mm2/s or less. In an experiment using the water emulsion method, oil is mixed with water at a rate of 72 to 28 in a shearing mixer for the production of a water emulsion of crude oil. It is found that a certain degree of stability is acquired using a surface active agent available on the market. Using this emulsion method, the crude oil is converted into a power generator fuel with a heating value of 6,775kcal/kg. The crude oil-turned product is a fine fuel superior to Orimulsion which is a fuel of the same type in terms of viscosity, amount of ash, and vanadium concentration. (NEDO)

  11. Optimization of Gamma-Ray Counting and Spectrometry in Biomedical Tracer Studies; Optimisation du Comptage et de la Spectrometrie des Rayons Gamma dans des Etudes Biomedicales Faites a l'Aide de Traceurs; Optimizatsiya gamma-scheta i spektrometrii gamma-luchej v biomeditsinskikh issledovaniyakh s pomoshch'yu indikatorov; Optimizacion del Recuento y de la Espectrometry Gamma en los Estudios Biomedicos con Indicadores

    Energy Technology Data Exchange (ETDEWEB)

    Guinn, V. P. [General Dynamics Corporation, San Diego, CA (United States)

    1965-10-15

    In biomedical tracer studies, especially in man and even more so in children and pregnant women, it is important to operate at the lowest possible level of administered radioisotope that is commensurate with the required precision and accuracy of the subsequent radioassay measurements. Similarly, with administered stable elements (as specified compounds) or enriched stable isotopes (again, in compound form), followed by radioactivation analysis of resulting samples, it is important from the toxicological standpoint to minimize the amounts of administered element. The problem of optimization of counting of one, two and three gamma-emitting radioisotopes, by Nal(Tl) scintillation counting, single-channel spectrometry and multichannel spectrometry, has been considered in some detail in these laboratories, with particular attention to single-, double-, or triple-tagging tracer studies with radioisotopes frequently used in biomedical studies: {sup 51}Cr, {sup 198}Au, {sup 75}Se, {sup 197}Hg, {sup 64}Cu, {sup 76}As, {sup 82}Br, {sup 59}Fe, {sup 60}Co, {sup 42}K, and {sup 24}Na. The same considerations apply to the widely-used thermal-neutron activation analysis determinations of the corresponding elements or enriched stable isotopes, so the results of these counting optimization calculations have a double usefulness. The calculations are based on a few reasonable assumptions made on practical biomedical considerations, namely: (1) small samples ({<=} 10 ml), (2) moderate counting periods (s 20 minutes), (3) modest allowable decay periods ({<=} 3 days) and (4) use of commercially available counting equipment and shielding. On this basis, the most sensitive methods of counting each of the aforementioned radioisotopes, and a number of pairs and trios of them, have been ascertained. The counting variables included in the considerations are: (1) type of Nal(Tl) crystal, i.e., solid or well-type, (2) size of Nal(Tl) crystal, up to a 5 in x 5 in size, (3) type of measuring equipment: simple scalar, single-channel pulse-height analyser, or multichannel pulse-height analyser. The minimum detectable sample specific activity has been computed for each optimum counting situation, as well as the levels needed for statistical accuracies (expressed as standard deviations) of {+-} 20%, {+-} 10%, {+-} 5%, and {+-} 2%. In a number of illustrative cases, the calculated limits have been compared with experimentally determined values. Special attention has been devoted to the best conditions for minimization of contributions from lead X-rays, backscattered gamma-rays, escape peaks, sample beta-particles, and Bremsstrahlung. (author) [French] Lorsqu'on fait des etudes biomedicales a l'aide de radioindi- cateurs, notamment chez l'homme et plus particulierement chez les enfants et les femmes enceintes, il importe de limiter autant que possible la quantite de radioisotopes administres au minimum necessaire pour assurer la precision et Texactitude des mesures ulterieures de la radioactivite des specimens biologiques. De meme, il importe, du point de vue toxicologique, de reduire au minimum la quantite d'elements stables (sous forme de composes specifies) ou de radioisotopes stables enrichis (egalement sous forme de composes) administres en vue de faire l'analyse par radioactivation des echantillons ulterieurement preleves. Les auteurs ont etudie de maniere assez approfondie, en laboratoire, le probleme de l'optimisation du comptage des radioisotopes emettant un, deux et trois rayons gamma, au moyen de scintillateurs a Nal(Tl), de spectrometres a un canal et de spectrometres multicanaux, et on s'est attache plus particulierement aux etudes avec marquage au moyen de un, deux ou trois traceurs en utilisant les radioisotopes d'usage frequent dans les etudes biomedicales: {sup 51}Cr, {sup 198}Au, {sup 75}Se, {sup 197}Hg, {sup 64}Cu, {sup 76}As, {sup 82}Br, {sup 59}Fe, {sup 60}Co, {sup 42}K, et {sup 24}Na. Les memes considerations valent pour la methode bien connue d'analyse par activation avec neutrons thermiques des elements ou des radioisotopes stables enrichis correspondants, de sorte que les resultats de ces calculs d'optimisation du comptage presentent une double utilite. Les calculs sont faits sur la base de quelques hypotheses raisonnables elles-memes fondees sur des constatations biomedicales pratiques: 1. emploi d'echantillons de dimensions reduites ( Less-Than-Or-Equal-To 10 ml), 2. duree moyenne des temps de comptage ( Less-Than-Or-Equal-To 20 min), 3. emploi de radioisotopes dont la periode de desintegration est assez breve ( Less-Than-Or-Equal-To 3) et 4. utilisation d'ensembles de comptage et de blindage en vente dans le commerce. Sur ces bases, on a determine les methodes de comptage les plus sensibles pour chacun des radioisotopes ci-dessus et pour des groupes de deux ou trois d'entre eux. Pour le comptage,. les variables sont les suivantes: 1. type du cristal de Nal(Tl), c'est-a-dire cristal normal ou cristal a puits, 2. dimensions du cristal de Nal(Tl), qui peuvent atteindre 13 x 13 cm, 3. type des appareils de mesure: echelle de comptage simple, analyseur d'amplitude a un seul canal ou a plusieurs canaux. On a calcule l'activife specifique minimale decelable des echantillons pour chaque situation optimale ainsi que les quantites necessaires pour atteindre le degre d'exactitude qu'exigent les statistiques: ecarts types de {+-} 20%, {+-} 10%, {+-} 5% et {+-} 2%. L'auteur compare dans plusieurs exemples les valeurs limites theoriques aux valeurs determinees experimentalement. Une attention particuliere a ete accordee aux meilleures conditions permettant de reduire au minimum la radioactivite des rayons X emis par le plomb, des rayons gamma retrodiffuses, des pics de fuite, des particules beta emises par les echantillons et du rayonnement de freinage. (author) [Spanish] En los estudios biomedicos con indicadores, especialmente cuando se efectuan en el hombre y, sobre todo, en el nino y en la mujer embarazada, es importante administrar la menor cantidad de radioisotopos compatible con una medicion suficientemente precisa de la radiactividad. Lo mismo sucede, por razones toxicologicas, cuando se administran elementos estables (en torma de compuestos) o isotopos estables enriquecidos (tambien en forma de compuestos) y se analizan por radiactivacion las muestras correspondientes. El autor ha estudiado con cierto detalle el problema de la optimizacion del recuento de uno, dos y tres radioisotopos emisores gamma por centelleo con Nal(Tl) y espectrometria mono y multicanal, prestando especial atencion a los estudios efectuados por marcacion simple, doble o triple con los radioisotopos mas frecuentemente usados en los estudios biomedicos: {sup 51}Cr, {sup 198}Au, {sup 75}Se, {sup 197}Hg, {sup 64}Cu, {sup 76}As, {sup 82}Br, {sup 59}Fe, {sup 60}Co, {sup 42}K, y {sup 24}Na. Como las mismas consideraciones son aplicables al analisis corriente por activacion con neutrones termicos de los elementos correspondientes o de los isatopos estables enriquecidos, los resultados de los calculos de la optimizacion del recuento tienen una utilidad doble. Esos calculos parten de unas pocas suposiciones razonables basadas en consideraciones biomedicas practicas: a) muestras pequenas ( Less-Than-Or-Equal-To 10 cm{sup 3}) ; b) tiempos de recuento de mediana duracion ( Less-Than-Or-Equal-To 10 minutos) ; c) cortos perfodos de espera antes de la medicion ( Less-Than-Or-Equal-To 3 dias) y d) empleo de equipo de recuento y blindaje de tipo comercial. Partiendo de esta base se ha determinado cuales son los metodos mas sensibles de recuento para los mencionados radioisotopos y para algunas combinaciones de dos o tres de ellos. El recuento se ha estudiado en funcion de las siguientes variables: a) tipo del cristal de Nal(Tl), macizo o de cavidad; b) tamafio del cristal de Nal(Tl), hasta 5 x 5 pulg; c) equipo de medicion: escalfmetro simple, analizador de amplitudes de impulso monocanal o multicanal. Para cada circunstancia Sptima de recuento se ha calculado la actividad especifica minima detectable de la muestra, asi como los niveles requeridos para las precisiones estadfsticas (expresadas como desviaciones tipo) de {+-} 20%, {+-} 10%, {+-} 5% y {+-}2% En varios casos se han comparado los limites calculados con valores experimentales. Se ha prestado especial atencion a las mejores condiciones para reducir al mfnimo las contribuciones de los rayos X generados en el plomo, de los rayos gamma retrodispersos, de los maximos de escape, de las particulas beta de las muestras y de las radiaciones de frenado. (author) [Russian] V biomedicinskih issledovanijah s pomoshh'ju indikatorov, osobenno ljudej i, tem bolee, detej i beremennyh zhenshhin, vazhno rabotat' pri naimenee nizkom urovne vvodimyh radioizotopov, naskol'ko jeto sovmestimo s trebuemoj tochnost'ju i pravil'nost'ju posledujushhih izmerenij radioaktivnosti. Analo- gichnym obrazom, v sluchae vvedenija v organizm stabil'nyh jelementov (v vide opredelennyh soedinenij) ili obogashhennyh stabil'nyh izotopov (opjat'-taki v vide soedinenij) dlja dal'- nejshego radioaktivacionnogo analiza poluchennyh prob, s tochki zrenija toksikologii vazhno sokrashhat' do minimuma kolichestvo vvodimogo jelementa. V laboratorijah byla tshhatel'no izuchena problema optimizacii otschityvanija odnogo, dvuh n treh gamma-izluchajushhih radioizotopov pri pomoshhi scintilljacionnyh schetchikov s kristallom NaJ(Tl), odnokanal'noj i mnogokanal'noj spektrometrii, prichem osoboe vni- manie udeljalos' issledovanijam pri pomoshhi mechenija odnim, dvumja ili tremja indikatorami, naibolee chasto ispol'zuemymi v bnomedicinskih issledovanijah, a imenno: hrom-51, zoloto-198, selen-75, rtut'-197, med'-64, mysh'jak-76, brom-82, zhelezo-59, kobal't-60, kal'cij-42 i natrij-24. Odinakovye soobrazhenija otnosjatsja k opredeleniju pri pomoshhi shiroko ispol'zuemogo aktivacionnogo analiza teplovymi nejtronami sootvetstvujushhih jelementov ili obogashhennyh stabil'nyh izotopov, tak chto rezul'taty jetih raschetov opti- mizacii otschityvanija imejut dvojnuju pol'zu. V osnovu raschetov byli polozheny prostye gipotezy, osnovannye prakticheskih bio- medicinskih soobrazhenijah: 1) malyj razmer prob (ne bolee 10 ml); 2) ogranichennoe vremja' otschityvanija (ne bolee 20 min); 3) nebol'shie dopustimye periody raspada (ne bolee treh sutok) i 4) ispol'zovanie imejushhegosja v prodazhe oborudovanija dlja otscheta i zashhity. Na jetoj osnove byli opredeleny naibolee chuvstvitel'nye metody otscheta dlja kazhdogo iz vysheupomjanutyh radioizotopov, a takzhe dlja ih par i troek. Uchityvalis' sledujushhie peremennye velichiny otscheta: 1) tip kristalla NaJ (T1), a imenno cel'nyj ili s kanalom, 2) razmer kristalla NaJ (T1)-do5h 5 djujmov i 3) tip izmeritel'nyh priborov: prostaja pereschetnaja shema, odnokanal'nyj i mnogokanal'nyj analizator amplitudy impul'sov. Dlja kazhdogo optimal'nogo uslovija otscheta podschitany minimal'naja ulovimaja udel'naja aktivnost' proby, a takzhe urovni ee, neobhodimye dlja sobljudenija statisticheskoj pra- vil'nosti (vyrazhennoj v vide standartnyh otklonenij) v predelah {+-}20, {+-}10, {+-}5 i {+-}2% . Dlja celogo rjada pokazatel'nyh sluchaev raschetnye predely byli sopostavleny s jeksperi- mental'nymi. Osoboe vnimanie udeljalos' nailuchshim uslovijam ponizhenija do minimuma doli izluchaemyh svincom rentgenovskih luchej, obratnogo rassejanija gamma-luchej, pikov utechki, chisla beta-chastic v probe i tormoznogo izluchenija. (author)

  12. Achievement report for fiscal 1999. Joint verification research on use for power generation of Omani superhigh-viscosity crude oil remaining unexploited; 1999 nendo Oman koku ni okeru miriyo chokonensei gen'yu no denryoku riyo ni kansuru kyodo jissho kenkyu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A Mukhaizna oil field remains to be exploited in Oman, with an estimated reserve of 2.4-billion barrels of very heavy oil with an API (American Petroleum Institute) specific gravity of 15.3. The viscosity of the oil is so high as to be over 100-thousand cP (at 15 degrees C). The extremely high viscosity causes its exploitable rate to be so low as 3%, and makes shipment by pipeline quite difficult. In this survey, a method using water emulsion is proposed for viscosity reduction, which aims to reduce the Mukhaizna crude oil viscosity to 200mm2/s or less. In an experiment using the water emulsion method, oil is mixed with water at a rate of 72 to 28 in a shearing mixer for the production of a water emulsion of crude oil. It is found that a certain degree of stability is acquired using a surface active agent available on the market. Using this emulsion method, the crude oil is converted into a power generator fuel with a heating value of 6,775kcal/kg. The crude oil-turned product is a fine fuel superior to Orimulsion which is a fuel of the same type in terms of viscosity, amount of ash, and vanadium concentration. (NEDO)

  13. Actual situation investigation utilizing a crude oil tanker for the air pollution in the Persion Gulf due to Kuwaiti oil field fire. Gen'yu tanker wo riyoshita Kuwait yusei kasai ni yoru Perushawan no taiki osen no jittai chosa

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, S. (Keio University, Tokyo (Japan). Faculty of Science and Technology)

    1992-01-10

    Very serious air pollution was brought about by the fire in oil fields at the end of February, 1991 after the Middle East Gulf War had come to an end. The present report explained the investigation result of actual air pollution situation obtained through measurement by implements mounted on board of the Japan Violet, crude oil tanker which made navigation in the Persian Gulf from 17 to 29 August, 1991. Non-marine salinity sulfate and nitrate in the dust particulates which are representative substances for the air pollution were 10.5 and 3.7[mu]g/m[sup 3], respectively in mean atmospheric content. Such a content level was nearly equal to that in the air-polluted land area and very high for the offshore air. It is judged to be resultant from the particulate formation of non-marine salinity salt from SO2 and NOx which were abundantly emitted, dispersed in the Persian Gulf and oxidized. However as a result of the neutralization by Ca contained in high content sanddust in the atmosphere of the Persian Golf, the acidity of sanddust was not so high. 7 refs., 8 figs., 1 tab.

  14. Stabilization by Shear and Negative V''; Stabilisation au Moyen du Croisement de Lignes de Champ et de l'Emploi d'un V'' Negatif; Stabilizatsiya spomoshch'yu shira i otritsatel'nogo V{sup ;} Estabilizacion por Cizallamiento y Empleo de V'' Negativa

    Energy Technology Data Exchange (ETDEWEB)

    Furth, H. P.; Killeen, J. [Lawrence Radiation Laboratory, Livermore, CA (United States); Rosenbluth, M. N. [General Atomic Division, General Dynamics Corporation and University of California (San Diego), La Jolla, CA (United States); Coppi, B. [University of California (San Diego), La Jolla, CA (United States)

    1966-04-15

    A criterion is derived for the stability against gravitational interchange of toroidal systems by using the hydrodynamic equation with finite resistivity. The stability depends on an expression that reduces to the sign of the second derivative of the volume per unit flux (V'') in the case that the plasma does not surround any ''floating'' conductors. If this condition is violated, then a ''rapid'' resistive instability results. If the condition is satisfied, then both the resistive growth rate and the critical {beta} against ''ballooning'' modes depend on a figure of merit rR{sub c}/L{sup 2} where r is plasma radius, L is length along field lines between ''good'' and ''bad'' regions, Re the mean radius of curvature and {gamma} is a shape factor depending on the design. A similar consideration applies to ''kinking'' modes. Using the results of numerical calculations, we will discuss the structure, stability properties and figure of merit of several ''stagnation-point'' solutions having the negative-V'' property. The principle here is to create directions of favorable {Delta}B, then cause the rotational transform to be weakened in the favorable regions (reaching a null at the stagnation point). The negative contributions to V'' are then weighted heavily, becoming infinite at the stagnation point. We consider three types of solution: (1) Linear periodic-multipole arrays, by using helical Script-Small-L = 2 and 4, or Script-Small-L = 3 ''shaping fields'' with natural stagnation points; and by superimposing Script-Small-L = 0 and 2, Script-Small-L = 1 and 3, or Script-Small-L = 0 and 3 ''corrugating fields'', to create favorable {Delta}B regions. (2) Helical equilibria, by using gross helical curvature to create the favorable VB regions and stagnating the rotational transform by means of a current on an axial conductor, around which the helical equilibrium flux-tube is wound. (3) Toroidal equilibria, by using the gross toroidal curvature to create the favorable {Delta}B regions. The rotational transform is generated by a helical Script-Small-L = 2 winding and stagnated by an auxiliary poloidal field. (author) [French] Les auteurs etablissent un critere de stabilite a l'egard de l'interchange gravitationnel dans les dispositifs torriidaux a l'aide de l'equation hydrodynamique dans laquelle on tient compte d'une reistivite finie. La stabilite depended'une expression qui se reduit au signe de la derivee seconde du volume par unite de flux (V'') lorsque le plasma n'entoure pas de conducteurs . Si cette condition n'est pas remplie, il se produit une instabilite resistive 'rapide'. Si elle l'est, le taux de croissance de l'instabilite resistive ainsi que la valeur critique de {beta} au-dela de laquelle se produit le mode de 'ballonnement' dependent d'un nombre caracteristique a (rR{sub c}/L{sup 2}) y ou r est le rayon de plasma, L la distance separant les 'bonnes' et les 'mauvaises' regions mesuree le long des lignes de forces, R{sub c} le rayon moyen de courbure et {gamma} un facteur de forme qui depend des details de la configuration. Des considerations semblables s'appliquent a des 'modes en serpentements ' . En se fondant sur les resultats de calculs numeriques, les auteurs etudient la structure, les proprietes de stabilite, ainsi que le nombre caracteristique de plusieurs solutions a 'points de stagnation ' pour lesquelles V'' est negatif. La methode consiste, dans ce cas, a creer des directions ou {Delta}B est favorable et a provoquer ensuite l'affaiblissement de la transformee rotationnelle dans les regions favorables (pour atteindre la valeur zero au point de stagnation). Les facteurs contribuant a rendre V'' negatif sont alors fortement ponderes et deviennent infinis au point de stagnation. Les auteurs examinent trois types de solutions: 1. Des dispositifs lineaires a multipoles periodiques, au moyen de 'champs modelants' helicoiedaux (du type Script-Small-L = 2 et 4 ou Script-Small-L = 3) presentant des points de stagnation naturels auxquels on superpose des 'champs de gaufrants' (du type Script-Small-L = 0 et 2, Script-Small-L = 1 et 3 ou Script-Small-L = 0 et 3), pour creer les regions a {Delta}B favorable. 2. Des equilibres helicoiedaux au moyen de la courbure heli'cbidale globale pour creer des regions a {Delta}B favorable, la stagnation de la transformee rotationnelle etant obtenue a l'aide d'un courant circulant sur un conducteur axial, autour duquel s'enroule le tube de flux en equilibre dont la forme est helicoiedale. 3. Des equilibres toroiedaux, au moyen de la courbure toroiedale globale, pour creer les regions a {Delta}B favorable. La transformee rotationnelle est engendree par un enroulement helicoiedal du type Script-Small-L = 2. Sa stagnation est obtenue par un champ poloiedal auxiliaire. (author) [Spanish] Se establece en la presente memoria un criterio de estabilidad respecto del intercambio gravitatorio en los sistemas toroidales, usando la ecuacion hidrodinamica en la cual se tiene en cuenta una resistividad finita. La estabilidad depende de una expresion que se reduce al signo de la derivada segunda del volumen por unidad de flujo (V'') en el caso de que el plasma no rodee a ningun conductor 'flotante'. Si esta condicionlno se cumple aparece una inestabilidad resistiva rapida mientras que, en caso contrario, tanto el indice de aumento de la inestabilidad resistiva como el valor critico de {beta} mas alla del cual se manifiesta el modo de 'inflacion' depende de un valor caracteristico Tilde-Operator rRc {gamma}/L{sup 2}, donde r es el radio del plasma, L la distancia que separa las zonas 'buenas' {gamma} 'malas', medida a lo largo de las lineas de fuerza, R{sub c} el radio de curvatura medio, y {gamma} un factor de forma que depende de detalles de la configuracion. Analogas consideraciones se aplican a los modos 'serpenteados'. Sobre la base de los resultados de los calculos numericos, los autores analizan la estructura, las propiedades de estabilidad y el valor caracteristico de varias soluciones de 'punto de estancamiento' para las cuales V'' es negativa. El metodo consiste en crear direcciones en que {Delta}B es favorable y debilitar luego la transformada rotacional en las regiones favorables (para alcanzar el valor cero en el punto de estancamiento). Los factores que contribuyen al valor negativo de V'' se ponderan entonces marcadamente, llegando a ser infinito en el punto de estancamiento. Los autores consideran tres tipos de solucion: 1) Disposiciones lineales de multipolos periodicos, mediante campos 'modeladores' helicoidales (del tipo Script-Small-L = 2 y 4 o Script-Small-L = 3) que presentan puntos de estancamiento naturales a los que se superponen 'campos de acanaladura' (del tipo Script-Small-L = 0 y 2, Script-Small-L s 1 y 3, o bien Script-Small-L = 0 y 3) pata crear regiones de {Delta}B favorable. 2) Equilibrios helicoidales, empleando la curvatura helicoidal de caracter global para crear las regiones de {Delta}B favorable y estancando la transformada rotacional mediante una corriente que circula por un conductor axial, alrededor del cual se arrolla el tubo de flujo en equilibrio, de forma helicoidal. 3) Equilibrios toroidales empleando la curvatura toroidal de caracter global para crear las regiones de {Delta}B favorable. La transformada rotacional se genera mediante un devanado helicoidal del tipo Script-Small-L = 2 y se logra el estancamiento mediante un campo poloidal auxiliar. (author) [Russian] Dlja ustojchivosti otnositel'no gravitacionnoj zhelobkovoj neustojchivosti toroidal'nyh sistem vyvoditsja kriterij putem ispol'zovanija gidrodinamicheskogo priblizhenija s konechnym udel'nym soprotivleniem. Ustojchivost' zavisit ot vyrazhenija, kotoroe svoditsja k znaku vtoroj proizvodnoj velichiny ob''ema na edinicu potoka (V''); v tom sluchae, kogda plazma ne okruzhena kakimi-libo ''plavajushhimi'' provodnikami. Esli jeto uslovie narushaetsja, to voznikaet ''bystraja'' rezistivnaja neustojchivost'. Esli jeto uslovie vypolnjaetsja, to kak dissipativnyj inkrement, tak i kriticheskoe {beta} dlja ''balonnyh'' mod zavisjat ot velichiny Tilde-Operator rRc {gamma}/L{sup 2} , gde g - radius plazmy, L - dlina vdol' linij polja mezhdu ''horoshimi'' i ''plohimi'' oblastjami, R{sub c} srednij radius krivizny i, nakonec, {gamma} formfaktor, zavisjashhij ot detal'noj konstrukcii. Podobnye soobrazhenija rasprostranjajutsja i na vintovye mody. Ispol'zuja rezul'taty chislennyh raschetov, my obsudim strukturu, ustojchivost' i preimushhestva neskol'kih reshenij so ''stacionarnoj tochkoj'', imejushhih otricatel'noe V''. Princip sostoit v tom, chtoby sozdat' napravlenija blagoprijatnogo VB, a zatem sozdat' vrashhatel'noe preobrazovanie, oslabljaemoe v blagoprijatnyh oblastjah (dostigaja 0 v stacionarnoj tochke). Otricatel'nye vklady v velichinu V'' priobretajut bol'shoj ves, stanovjas' beskonechnymi v stacionarnoj tochke. Rassmatrivajutsja tri tipa reshenija: 1) Linejnye periodicheski-mul'tipol'nye rjady S ispol'zovanija vintovyh 1 = 2 i 4, ili 1=3 ''formirujushhih polej'' s estestvennymi stacionarnymi tochkami; i putem nalozhenija 1 = 0 i 2, 1 = 1 i 3, ili 1 = 0 i 3 ''gofrirujushhih polej'', dlja togo, chtoby sozdat' blagoprijatnye oblasti {Delta}B. 2) Vintovoe ravnovesie putem ispol'zovanija bol'shoj vintovoj krivizny s cel'ju sozdanija blagoprijatnyh oblastej {Delta}B i ostanovki vrashhatel'nogo preobrazovanija s pomoshh'ju toka na osevom provodnike, vokrug kotorogo navita vintovaja trubka dlja ravnovesnogo potoka. 3) Toroidal'noe ravnovesie s ispol'zovaniem bol'shoj toroidal'noj krivizny dlja sozdanija blagoprijatnyh oblastej {Delta}B. Vrashhatel'noe preobrazovanie sozdaetsja s pomoshh'ju spiral'nyh vitkov 1 =2 i stacionarnaja tochka obrazuetsja blagodarja vspomogatel'nomu poloidal'nomu-polju. (author)

  15. Report on the survey of the project on the environmentally friendly type energy community field test. Separate volume - reference data. Investigative project for development and commercialization of recycle technology of waste edible oil; 2001 nendo kankyo chowa gata energy community field test jigyo chosa hokokusho. Hai shokuryo yu no recycle gijutsu kaihatsu to jitsuyoka no tameno chosa jigyo (Bessatsu - Sanko shiryo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-06-01

    For the purpose of promoting the effective utilization of biomass resource, an investigative study was made on the development of recycle technology of waste edible oil. In the survey, the following were carried out and the results were summarized: promotion measures for biodiesel oil by the EU, promotion measures for biodiesel oil by other countries including Canada, promotion measures for biodiesel oil by the US's Department of Energy (DOC), actual results of the use of biodiesel oil in Kyoto City, reference data on biodiesel oil in Japan, and tackling toward the promotion of BDF in the Ministry of Agriculture, Forestry and Fisheries. As to the transportation use fuel in the EU in the coming 20 years, biofuel, natural gas and hydrogen seem to be selected. If measures are positively taken, biofuel is expected to be 2%, 6%, 7% and 8% in FY 2005, FY 2010, FY 2015 and FY 2020, respectively. Also, natural gas is expected to be 2% in FY 2010, 5% in FY 2015 and 10% in FY 2020, and hydrogen is expected to be 2% in FY 2015 and 5% in FY 2020. (NEDO)

  16. Study of pentane and cyclopentane radiolysis with the aid of radioactive iodine; Etude de la radiolyse du pentane et du cyclopentane a l'aide d'iode radioactif; Issledovanie radioliza pentana i tsiklopentana s pomoshch'yu radioaktivnogo joda; Estudio de la radiolisis del pentano y del ciclopentano con ayuda de yodo radiactivo

    Energy Technology Data Exchange (ETDEWEB)

    Dauphin, J [Laboratoire de Chimie-Physique, Faculte des Sciences de Paris (France)

    1962-03-15

    Irradiation of hydrocarbons by ionizing radiation such as Co{sup 60} gamma-rays produces, inter alia, free radicals. Analysis of these radicals may lead to at least a partial explanation of the phenomena occurring. For analysis, the ''isotopic dilution'' method is used: the iodine used for taking up the radicals is labelled with iodine-131, resulting in a whole series of labelled iodides when the reaction is completed. Separation is affected by means of distillation on a microcolumn after inactive carriers have been added and the mineral iodine has been extracted. The activity of each fraction is measured directly it leaves the column. A control is used to obtain absolute G values from the counting. Precautions are taken to prevent isotopic exchange during separation. This method has been applied to cyclopentane and n-pentane and has yielded a detailed radiolysis spectrum. (author) [French] Les hydrocarbures irradies par des rayonnements ionisants tels que les {gamma} du cobalt-60 produisent entre autres entites des radicaux libres, dont l'analyse peut amener a decouvrir une explication au moins partielle des phenomenes. Pour effectuer cette analyse, on utilise la technique de la : l'iode servant de capteur est marque par de l'iode-131, ce qui a pour resultat de donner toute une serie d'iodures marques en fin de reaction. La separation se fait par distillation sur une microcolonne, apres addition d'entraineurs inactifs et extraction de l'iode mineral. L'activite de chaque fraction est mesuree directement a la sortie de la colonne. Un temoin permet l'obtention de valeurs absolues de G a partir des comptages. Des precautions sont prises pour eviter l'echange isotopique en cours de separation. Appliquee au cyclopentane et au n-pentane, cette methode a permis d'obtenir un spectre detaille de radiolyse. (author) [Spanish] La exposicion de los hidrocarburos a la accion de radiaciones ionizantes tales como los rayos gamma del {sup 60}Co da lugar a la formacion de radicales libres. Es posible que el analisis de estos radicales permite explicar, por lo menos parcialmente, los fenomenos observados. El autor efectua el analisis por : el yodo empleado como receptor se marca con yodo-131, por lo que al final de la reaccion se obtiene toda una serie de yoduros marcados. Lleva a cabo la separacion por destilacion en una microcolumna despues de haber anadido portadores inactivos y extraido el yodo inorganico. La actividad de cada fraccion se mide directamente a la salida de la columna. Los valores absolutos del coeficiente G se determinan por recuento de la actividad de una muestra testigo. El autor adopta las precauciones necesarias para evitar el intercambio isotopico durante la separacion. El metodo se aplico al ciclopentano y al n-pentano, habiendose obtenido un espectro de radiolisis detallado. (author) [Russian] Uglevodorody, obluchennye ioniziruyushchimi luchami, takimi, kak gamma-luchi kobal'ta-60, sredi drugikh veshchestv dayut svobodnye radikaly. Analiz ehtikh radikalov mozhet privesti k chastichnomu ob{sup y}asneniyu yavlenij. CHtoby osushchestvit' ehtot analiz, primenyayut metod ''izotopnogo razbavleniya'': jod, sluzhashchij ulovitelem, metyat jodom-131, chto privodit k tomu, chto v kontse reaktsii poluchaetsya tselaya seriya mechenykh jodidov. Razdelenie osushchestvlyaetsya peregonkoj na mikrokolonnom apparate posle dobavleniya neaktivnykh nositelej i izvlecheniya svobodnogo joda. Aktivnost' kazhdoj fraktsii izmeryaetsya pryamo posle vykhoda iz kolonki. Znak daet vozmozhnost' poluchit' absolyutnye znacheniya G ot nachala scheta. Byli prinyaty mery predostorozhnosti, chtoby izbezhat' izotopnogo obmena vo vremya razdeleniya. EHtot metod primenyalsya k tsiklopentanu i k p-pentanu i pozvolil poluchit' podrobnyj spektr radioliza. (author)

  17. The Possibility of Making a Quantitative Study of the Precipitin Reaction by Gamma-Radioactive Tracers; Possibilite d'une Etude Quantitative de la Reaction de Precipitation par Marquage a l'Aide d'Emetteurs Gamma; Vozmozhnost' kolichestvennogo opredeleniya reaktsii osazhdeniya s pomoshch'yu gamma-radioaktivnykh indikatorov; Estudio Cuantitativo de la Reaccion de Precipitacion con Ayuda de Indicadores Gamma

    Energy Technology Data Exchange (ETDEWEB)

    Bonev, L.; Todorov, S.; Robev, S. [Nauchno-Issledovatel' skij Institut Radiologii i Radiacionnoj Bezopasnosti, Sofija (Bulgaria)

    1965-10-15

    The paper presents the first results of the quantitative determination of the precipitin reaction (formation of an antigen-antibody complex) by labelling the precipitating components with gamma-radioactive tracers which do not chemically interact with albuminous molecules. As tracers it is possible to use chrome-manganese and nickel-copper compounds, whose tendency to hydrolyze permits the fixation of the radioactive tracer on the antigen and antibody respectively. The radioactivity of the components is determined by a multichannel pulse-height analyser. The results obtained show that the precipitation curve, plotted on the basis of radiometric data, closely corresponds to the curve plotted by the well-known quantitative methods used to determine albumin. The paper discusses the possibilities of using the method described. (author) [French] Les auteurs communiquent les premiers resultats d'une etude quantitative qu'ils ont faite de la reaction de precipitation (formation du complexe antigene-anticorps) en marquant les composants du precipites avec des emetteurs gamma qui ne reagissent pas chimiquement avec les molecules d'albumine. Pour le marquage, on peut utiliser des composes de chrome/manganese ou de fer qui subissent facilement l'hydrolyse et assurent de ce fait la fixation de la substance radioactive sur l'antigene et, partant, sur l'anticorps. La radioactivite des composants est determinee a l'aide d'un selecteur d'amplitudes a plusieurs canaux. Les resultats montrent que la courbe de precipitation obtenue avec les donnees radiometriques concorde parfaitement avec celle que l'on obtient par les methodes quantitatives connues servant au dosage de l'albumine. Les auteurs discutent les possibilites d'application de la methode etudiee. (author) [Spanish] Los autores presentan los primeros resultados de un estudio cuantitativo de la reaccion de precipitacion (formacion del complejo antigeno-anticuerpo) que efectuaron marcando los componentes de precipitacion con indicadores gamma que no reaccionan quimicamente con las moleculas de albumina. Como indicadores pueden utilizarse ciertos compuestos de cromo, manganeso y hierro que, por su teridencia a hidrolizarse, permiten fijar el indicador radiactivo en el antigeno y en el anticuerpo, respectivamente. La radiactividad de los componentes se determino con ayuda de un analizador multicanal de amplitud de impulsos. Los resultados obtenidos demuestran que la curva de precipitacion, trazada sobre la base de los datos radiometricos, concuerda con la que se obtiene por los metodos cuantitativos corrientemente empleados en la valoracion de la albumiRa. Los autores examinan las posibilidades de aplicacion del metodo descrito. (author) [Russian] Soobshhajutsja pervye rezul'taty kolichestvennogo opredelenija reakcii osazhdenija (obrazovanija kompleksa antigen-antitelo) posredstvom mechenija precipitacionnyh komponentov gamma-radioaktivnymi indikatorami, ne vstupajushhimi v himicheskoe vzaimodejstvie s belkovymi molekulami. V kachestve indikatorov mogut byt' ispol'zovany hromomargancevye soedinenija i soedinenija zheleza, sklonnost' kotoryh k gidrolizu obespechivaet fiksaciju radioaktivnogo indikatora na antigene sootvetstvenno i na antitelo. Opredelenie radioaktivnosti komponentov proizvoditsja posredstvom mnogokanal'nogo amplitudnogo analizatora. Poluchennye rezul'taty pokazyvajut, chto precipitacionnaja krivaja, postroennaja na osnovanii radiometrichnyh dannyh, nahoditsja v blizkom sootvetstvii s krivoj, postroennoj izvestnymi kolichestvennymi metodami, sluzhashhimi dlja opredelenija belka. Rassmatrivajutsja vozmozhnosti primenenija jetogo metoda na praktike. (author)

  18. ASSOTsIATsIYa GENETIChESKOGO POLIMORFIZMA GENOV RETsEPTORA VITAMINA D (VDR, KOLLAGENA AI TsEPI KOLLAGENA A I TIPA (COL1A1, I FAKTORA NEKROZA OPUKhOLE-A (TNFA I SOSTOYaNIYa MINERALIZATsII SKELETA U DETEY S BOLEZN'Yu KRONA

    Directory of Open Access Journals (Sweden)

    TV GABRUSSKAYa

    2016-08-01

    Full Text Available Болезнь Крона (БК - тяжелое аутоиммунное заболевание желудочно-кишечного тракта, влияющее на качество жизни, развитие ребенка и характеризующееся высоким риском инвалидизации. Изменения состояния костной ткани у пациентов с БК являются нередкими и проявляются задержкой линейного роста, снижением показателей минерализации скелета, изменениями костного метаболизма, повышенным риском низкоэнергетических переломов. Изменения костной ткани обусловлены сочетанием факторов болезни (мальабсорбция, терапия кортикостероидами, дефицит витамина D, низкая двигательная активность, дефицит инсоляции, задержка полового развития и генетических факторов, регулирующими костный метаболизм. Цель: проанализировать наличие ассоциации между показателями костного метаболизма и носительством полиморфных генетических маркеров генов VDR, COL1A1, TNFa. Материал и методы. В исследование включено 44 ребенка с БК (25 мальчиков и 19 девочек в возрасте от 3 до 17 лет. Исследование минерализации скелета осуществлялось методом двуэнергетической рентгеновской абсорбциоме-трии поясничного отдела позвоночника L1-L4 (денситометр Hologic QDR 4500C, оснащенный педиатрической референтной базой. Молекулярно-генетические исследования: определение 1546G/T полиморфизма гена al цепи коллагена I типа (COL1A1, TaqI полиморфизма гена рецептора витамина D (VDR, -308G/A полиморфизм гена фактора некроза опухолей-a (TNF-a осуществлялось методом полимеразной цепной реакции с последующим рестрикционным анализом. Оценивались показатели минеральной плотности кости (МПК, оцениваемые при помощи Z критерия (МПК-Zscore, дефицит МПК в процентах, частота низкой МПК (НМПК, которая определялась как МПК-Zscore < - 2 SD. Результаты. При изучении частот распределения полиморфных генотипов изученных генов у детей с НМПК и без, не было выявлено достоверных различий в общей группе, а также среди мальчиков и девочек. В показателях МПК-Zscore среди носителей TaqI полиморфных генотипов гена VDR в общей группе (р=0,51, группе мальчиков (р=0,7 и девочек (р=0,68. Среди носителей полиморфных 1546G/T генотипов гена (COL1A1 также не было выявлено различий в показателях МПК-Zscore в общей группе (р=0,79, группе мальчиков (р=0,42 и девочек (р=0,95. При изучении ассоциации -308 G/A полиморфизма гена TNF-a выявлено, что, пациенты, носители гетерозиготного генотипа m/n по сравнению с носителями гомозиготного генотипа n/n имели более низкие показатели МПК: МПК-Zscore = -2,35 SD (-3,4; -1,35 и -1,4 SD (-2,3; -0,5, p=(0,1, соответственно и дефицит МПК: -28,0% (-43,0; -15,5 и -11,5% (-22,5; -6,0, (р=0,034, соответственно Выводы. Выявлена ассоциация гетерозиготного полиморфного генотипа m/n гена -308 G/A TNF-a с более выраженными нарушениями МПК у детей с БК. Требуется продолжение исследований для уточнения роли полиморфных маркеров генов в реализации нарушений МПК у детей с БК.

  19. Pulsed Source Measurements on a Uranium-Water Subcritical Assembly; Mesures Faites sur un Assemblage Sous- Critique Uranium-Eau Ordinaire a l'Aide d'une Source Pulsee; Izmereniya s pomoshch'yu istochnikov impul'snykh nejtronov na urano-vodnoi podkriticheskoi sborke; Mediciones con Fuentes Pulsantes en un Conjunto Subcritico Uranio-Agua

    Energy Technology Data Exchange (ETDEWEB)

    Gibson, I. H.; Walker, J. [Department of Physics, University of Birmingham, Birmingham (United Kingdom)

    1964-02-15

    An unreflected assembly of natural uranium and light water has been used in conjunction with a pulsed source of neutrons for decay-time measurements at different bucklings. Four different lattice pitches over the range 3.94 cm to 5.08 cm were obtained by using different pairs of accurately machined lattice plates and in each case the uranium was in the form of bars 109.8 cm long and 3.0 cm diameter. The fuel- was mounted horizontally and loadings up to approximately 6 t were involved. Spatial harmonics were eliminated or selected by appropriate placing of a small scintillation detector. Experimental results showing the dependence of decay constant on buckling are presented and compared with theoretical values. (author) [French] On a utilise conjointement un assemblage sans reflecteur uranium naturel-eau ordinaire et une source puisee en vue de mesurer le temps de decroissance pour differents laplaciens. - Plusieurs paires de plaques de reseau usinees avec precision ont permis d'adopter quatre differents pas de reseau allant de 3,94cm a 5,08 cm; dans chaque cas, l'uranium etait sous forme de barres de 109,8 cm de long et de 3,0 cm de diametre. Le combustible etait monte horizontalement et le chargement a atteint parfois jusqu'a pres de 6 t. Grace a un petit detecteur a scintillations convenablement place, on a pu eliminer les harmoniques spatiaux ou les selectionner. Les auteurs presentent des resultats d'experiences qui montrent les variations de la constante de desintegration en fonction du laplacien, et les comparent avec les valeurs theoriques. (author) [Spanish] Los autores utilizaron un conjunto de uranio natural y agua ligera, sin reflector, juntamente con una fuente neutronica pulsante, para efectuar determinaciones del tiempo de desintegracion en correspondencia con diferentes valores del laplaciano. En este conjunto se pueden establecer cuatro diferentes espaciamientos del reticulado, desde 3,94 cm hasta 5,08 cm. utilizando diferentes pares de placas de reticulado rectificadas con precision; en todos los casos el uranio adopta la forma de barras de 109,8 cm de largo por 3,0 cm de diametro. El combustible se monta horizontalmente, alcanzando el peso de las cargas hasta unas 6 t. Se eliminan, o eligen a voluntad, los armonicos espaciales ubicando convenientemente un pequeno detector de centelleo. Los autores presentan resultados experimentales que indican la relacion de dependencia existente entre la constante de desintegracion y el laplaciano y los comparan con los valores hallados teoricamente. (author) [Russian] Sborka na prirodnom urane i legkoj vode bez otrazhatelja ispol'zuetsja sovmestno s istochnikom impul'snyh nejtronov dlja izmerenija vremeni raspada pri razlichnyh znachenijah laplasiana. Chetyre razlichnyh shaga reshetki na otrezke 3,94 - 5,8 sm byli polucheny putem ispol'zovanija razlichnyh par horosho obrabotannyh plastinok reshetki, v kazhdom sluchae uran byl v vide sterzhnej dlinoj 109,8 i diametrom 3,0 sm. Sterzhni ustanavlivalis' gorizontal'no, ves zagruzok sostavljal priblizitel'no 6 t. Prostranstvennye kolebanija ustranjalis' ili vydeljalis' putem sootvetstvujushhego ustanovlenija nebol'shogo scintilljacionnogo detektora. Budut predstavleny i sravneny s teoreticheskimi dannymi rezul'taty opytov, pokazyvajushhie zavisimost' postojannoj raspada ot laplasiana. (author)

  20. Industrial Ultrasonic Inspection of Stainless-Steel Claddings for the EL4 Reactor; Controle Industriel par Ultrasons des Gaines en Acier Inoxydable du Reacteur EL4; Promyshlennyj kontrol' obolochechnykh trub iz nerzhaveyushchej stali reaktora dlya EL4 s pomoshch'yu ul'trazvukovogo metoda; Metodos Ultrasonicos para Control Industrial de las Vainas de Acero Inoxidable del Reactor EL4

    Energy Technology Data Exchange (ETDEWEB)

    Prot, A. C.; Foulquoer, H. E.; Peyrot, J. P. [Centre d' Etudes Nucleaires de Saclay (France)

    1965-09-15

    Improved reactor performance requires the use of accurately fabricated and carefully inspected components. One inspection relates to the quality of the cladding tubes, whose mechanical reliability is essential for economic reactor operation. The choice and development of a method is a difficult matter and the authors explain the main factors involved. Once the choice has been made and the method has been developed in the laboratory, two new problems arise: Adaptation to meet industrial requirements; and The need to reconcile the quality standards attainable with the manufacturing process at any given stage and the somewhat arbitrarily defined specifications for the finished product. In practice, this involves a statistical study of batches of tubes from various sources and their classification in relation to more or less strict thresholds. The number of tubes which have to be inspected is much larger than originally expected. This has led to the design of an automatic inspection device geared both to the output rates involved and to the requirements of the type of inspection adopted; the latter are generally mechanical and impose particularly careful product fabrication. These various characteristics are now embodied in a device whose capacity can already easily meet the requirements of a fuel-element production line. The potentialities of the device are closely dependent on the characteristics of the inspection equipment used, especially the performances of the electronic part of ultrasonic inspection instruments and of the transducers. This study shows that standard equipment is not very suitable and that immediate thought should be given to special instruments for this type of inspection. (author) [French] L'accroissement des performances des reacteurs necessite l'utilisation de materiaux finement elabores et soigneusement controles. L'un des aspects de ce controle est celui de la qualite des tubes de gainage utilises, dont la tenue mecanique est un facteur essentiel de rentabilite du reacteur. Il s'avere que le choix de la methode a utiliser et a mettre au point est delicat; le memoire en donne les elements essentiels. Ce choix etant fait, apres mise au point en laboratoire, deux nouveaux problemes se posent: - la transposition dans le domaine industriel; - la necessite de tenir compte de la qualite permise, a un instant determine, par les procedes de fabrication, en relation avec les normes de reception definies de maniere plus ou moins arbitraire. Ceci se traduit en fait par la necessite d'une etude statistique sur des lots de tubes de diverses provenances, et leur classement par rapport a des seuils plus ou moins severes. On verra que le nombre de tubes a controler est tres superieur a celui prevu initialement. Cela conduit a l'etude d'une machine de controle automatique, capable de satisfaire a la fois les exigences de cadence et celles propres au type de controle choisi: ces dernieres sont generalement d'ordre mecanique et necessitent une construction particulierement soignee. L'ensemble de ces considerations a conduit a concevoir une machine dont la cadence peut des maintenant couvrir sans difficulte les besoins d'une chaihe de fabrication d'elements combustibles. Les possibilites de cette machine sont etroitement liees aux caracteristiques du materiel de controle choisi, en particulier aux performances de l'electronique des appareils de controle par ultrasons et a celles des traducteurs utilises. Il resulte d'ailleurs de cette etude que le materiel standard ne repond que tres imparfaitement au probleme et que l'on doit envisager des maintenant un appareillage particulier pour ce type de controle. (author) [Spanish] Las mayores exigencias a que se someten los reactores obligan a utilizar materiales elaborados y controlados con sumo cuidado. Un aspecto de tal control se refiere a la calidad de las vainas empleadas, cuyas propiedades mecanicas ejercen una influencia decisiva sobre la rentabilidad del reactor. La eleccion del metodo a utilizar representa un proceso delicado, cuyas consideraciones fundamentales se exponen en el presente trabajo. Una vez elegido el metodo y puesto a punto en el laboratorio, surgen dos nuevos problemas: Transposicion a escala industrial. Necesidad de tener siempre presente la calidad que puede alcanzarse en la industria, en relacion con normas de aceptacion definidas de manera mas o menos arbitraria. En la practica, ello obliga a realizar un estudio estadistico sobre partidas de tubos de diversos origenes y clasificarlos teniendo en cuenta umbrales de aceptacion de distintos grados de severidad. Como se ve en el trabajo, el numero de tubos a controlar es muy superior al previsto inicialmente. Este hecho indujo a estudiar una maquina de control automatico, capaz de satisfacer al mismo tiempo las exigencias de la cantidad y las propias del tipo de control seleccionado; estas ultimas son por lo general de orden mecanico y requieren una construccion especialmente esmerada. El conjunto de estas consideraciones llevo a concebir una maquina capaz de satisfacer sin dificultad las necesidades de una cadena de fabricacion'de elementos combustibles. Las posibilidades de esta maquina estan estrechamente ligadas a las caracteristicas del material descontrol escogido, sobre todo al rendimiento de los circuitos electronicos correspondientes a los aparatos de control por metodos ultrasonicos y al de los transductores utilizados. Se deduce del presente estudio, por otra parte, que el material corriente no responde al problema sino de manera muy imperfecta, y que se debe encarar desde ya el proyecto de un aparato especial para este tipo de control. (author) [Russian] Uluchshenie rabochih harakteristik reaktorov trebuet primenenija tshhatel'no razrabotannyh i strogo kontroliruemyh materialov. Odnim iz aspektov jetogo kontrolja javljaetsja kachestvo ispol'zuemyh pokrytij dlja trub, mehanicheskoe sostojanie kotoryh predstavljaet soboj sushhestvennyj faktor rentabel'nosti reaktorov. Podtverzhdaetsja, chto vybor metoda, kotoryj sleduet primenjat' i razrabatyvat', javljaetsja trudnym. Privodjatsja osnovnye momenty. Posle togo, kak v rezul'tate laboratornyh rabot sdelan vybor, voznikajut dve novye problemy: D) vnedrenie v promyshlennost' neobhodimost' ucheta dopustimogo kachestva v opredelennyj moment metodami izgotovlenija v svjazi s ustanovlennymi bolee ili menee proizvol'nym obrazom normami dlja priema. Jeto, v dejstvitel'nosti, obuslavlivaetsja neobhodimost'ju v statisticheskom issledovanii komplektov trub razlichnogo izgotovlenija i ih klassifikacii po otnosheniju k bolee ili menee strogim normam. Vidno, chto kolichestvo podlezhashhih kontrolju trub znachitel'no prevyshaet pervonachal'no namechennoe. Jeto vedet k izucheniju avtomaticheskogo kontrol'nogo mehanizma, sposobnogo udovletvorit' odnovremenno i trebovanijam tempa, i trebovanijam, vytekajushhim iz vybrannogo tipa kontrolja: poslednie obychno svodjatsja k mehanicheskomu kontrolju i nuzhdajutsja v osobenno tshhatel'no razrabotannoj konstrukcii. Sovokupnost' jetih soobrazhenij privela k razrabotke ustrojstva, temp raboty kotorogo uzhe sejchas mozhet bez truda pokryt' potrebnosti vsego cikla proizvodstva toplivnyh jelementov. Vozmozhnosti jetogo ustrojstva tesno svjazany s harakteristikami podobrannogo oborudovanija navedenija i kontrolja, v osobennosti so svojstvami jelektroniki priborov kontrolja po ul'trazvuku i so svojstvami ispol'zuemyh preobrazovatelej. K tomu zhe iz jetogo issledovanija javstvuet, chto standartnoe oborudovanie daleko ne sootvetstvuet probleme i chto uzhe sejchas sleduet predusmotret' osoboe ustrojstvo dlja dannogo tipa kontrolja. (author)

  1. The Design and Performance of a Large High resolution Focusing Collimator; Etude d'un Grand Collimateur a Focalisation et Fort Pouvoir de Resolution: Resultats; Konstruktsiya i kharakteristika krupnogo fokusiruyushchego kollimatora s vysokoj stepen'yu razresheniya; Diseno y Funcionamiento de un Gran Colimador Enfocado de Alto Poder de Resolucion

    Energy Technology Data Exchange (ETDEWEB)

    Harris, C. C.; Bell, P. R.; Satterfield, M. M.; Ross, D. A.; Jordan, J. C. [Oak Ridge National Laboratory, TN (United States)

    1964-10-15

    The primary reason for use of a ''focusing collimator'' is to permit the use of a large detector giving increased counting rate without loss of spatial resolving power. Since many apertures aimed at a common point are used, a sort of ''focusing'' effect is achieved. Because the septa between the apertures are necessarily thin, penetration of these walls by gamma rays causes a loss of spatial resolution. Tungsten and gold have been used (for 3-in-diam. detectors) to reduce this penetration as compared with lead. Reducing penetration by using a longer lead collimator damages the main design objective, that of increased counting rate, unless a larger detector is also used. We have designed and constructed a 91-hole lead collimator for use with a 5.25-in (13. 5 cm) by 3-in (7.5 cm) NaI(Tl) detector. The focal point is 9.5 in (24 cm) from the detector, and the solid angle of ac ceptance is the same as focusing collimators in common use with 3 -in detectors. The maximum length is 6.5 in (16.5 cm); normal design length is 5.5 in (14 cm). At these lengths, the optical ''circles of resolution'' are 0.476 in (1.2 cm) and 0. 304 in (0.77 cm) respectively. The designs achieved the following: (1) A longer focal distance with an increase of counting efficiency due to the larger phosphor; (2) a lead collimator with a resolving power comparable with shorter gold c o llimators (a scan of a point source of Cs-Ba{sup 137} appears only 7 mm in diam.); (3) a high-resolution collimator for human and small animal scanning; (4) a basic assembly design for use with larger-solid-angle collimators for increased counting efficiency. Total-body scans have been made with Au{sup 198} and I{sup 131}. The scans indicate the increased efficiency and resolution of the 5.5-in collimator. A scan (Au198) of a dog with the 6.5 - in collimator showed well a concentration of activity apparently less than 1/4 in (6 mm) in diam.; the activity was only five times ''body background'' but was clearly separated by 1/4 in from a |- in diam. source about 50 times more intense. (author) [French] Le collimateur a focalisation a pour principal avantage de permettre l'emploi d'un grand detecteur pour augmenter le taux de comptage sans diminuer la resolution dans l 'espace. Un grand nombre d 'orifices etant orientes vers un point unique, on obtient une sorte d'effet ' d e focalisation ' Etant donne que les parois entre les orifices sont obligatoirement minces, la penetration de ces parois par les rayons gamma provoque une diminution de la resolution dans l'espace. Afin d'attenuer cette penetration, on a utilise, au lieu de plomb, le tungstene et l 'or pour les detecteurs de 7,5 cm de diametre. A moins d'utiliser aussi un plus grand detecteur, le fait d'utiliser un collimateur en plomb plus long pour reduire la penetration compromet l 'objectif essentiel de l 'etude de l 'appareil; qui est d'augmenter le taux de comptage. Les auteurs ont etudie et construit un collimateur en plomb, a 91 orifices, destine a etre utilise avec un detecteur a NaI(Tl) de 13,5 cm sur 7,5 cm. Le foyer est a 24 cm detecteur, et l'angle solide d'acceptation est le meme que pour les collimateurs a focalisation utilises couramment avec des detecteurs de 7,5 cm. La longueur maximum est de 16,5 cm; la longueur normale de l 'appareil etudie est de 14 cm. A ces longueurs, les 'cercles de resolution'optiques sont de 1,2 cm et 0,77 cm, respectivement. Les resultats de l 'etude sont les suivants: a) distance focale plus longue et augmentation de l 'efficacite de comptage, grace a l'emploi d'un scintillateur de plus grandes dimensions; b) collimateur en plomb, avec resolution comparable a c elle de collimateurs en or, plus courts (sur le scintigramme, l'image d'une source ponctuelle de Cs-{sup 137}Ba ne mesure que 7 mm de diametre); c) collimateur a fort pouvoir de resolution, pour la scintigraphie de l'homme et des petits animaux; d) ensemble standard destine a etre utilise avec des collimateurs a plus grand angle solide, en vue d'augmenter l'efficacite de comptage. Des scintigrammes de l'organisme entier ont ete obtenus au moyen de '{sup 198}Au et de {sup 131}I. Ces scintigrammes montrent que le collimateur de 14 cm a une plus grande efficacite et une plus grande resolution. Sur un scintigramme ({sup 198}Au) de chien obtenu au moyen du collimateur de 16,5 cm, on a discerne nettement une zone active d'un diametre apparent inferieur a 6 mm; l'activite n'etait que cinq fois superieure au bruit de fond du aux tissus, mais la zone active etait nettement separee par un espace d 0,6 cm d'une source environ cinquante fois plus intense ayant un diametre de 1,8 cm. (author) [Spanish] Los 'colimadores enfocados' permiten utilizar detectores de grandes dimensiones que dan un indice de recuento mayor sin perdida del poder de resolucion espacial. Como estos colimadores tienen muchos canales dirigidos hacia un mismo punto se obtiene con ellos una especie de efecto 'de enfoque'. Los tabiques de esc' canales son necesariamente delgados y, por consiguiente, le' rayos gamma los atraviesan en detrimento de la resolucion espacial. A fin de reducir esa penetracion se han empleado, para detectores de 3 pulg de diametro, colimadores de wolframio y oro, de preferencia a los de plomo. Si se reduce la penetracion empleando un colimador de plomo mas largo se malogra la finalidad perseguida ya que el indice de recuento disminuye, a no ser que se emplee tambien un detector de mayores dimensiones. Los autores han disenado y construido un colimador de plomo de 91 canales para emplearlo con un detector de Nal(Tl) de 5,25 pulg (13,5 cm) por 3 pulg (7,5 cm). El foco esta situado a 9,5 pulg (24 cm) del detector, y el angulo solido de admision es igual al de los colimadores enfocados que se emplean corrientemente con detectores de 3 pulg. La longitud maxima es de 6,5 pulg (16 ,5 cm); la normal es de 5,5 pulg (14 cm). Para estas longitudes, los 'circulos de resolucion' opticos son, respectivamente, de 0.476 pulg (1,2 cm) y 0,304 pulg (0,77 cm). Se han logrado las siguientes mejoras: a) un incremento de la distancia focal con un aumento de la eficacia de recuento debida al empleo de un cristal de mayores dimensiones; b) un colimador de plomo con un poder de resolucion comparable al de los colimadores de oro mas cortos (la imagen de una fuente puntiforme de Cs-137 Ba tiene solo 7 mm de diametro) ; c) un colimador de alto poder de resolucion para la exploracion en seres humanos y animales pequenos; d) una estructura basica disenada de modo que permite emplear co limadores de angulo solido mayor para incrementar la eficacia de recuento. Se han efectuado exploraciones del organismo entero con oro-198 y yodo-131. Las imagenes indican una mejora de la eficacia y del poder de resolucion del colimador de 5 ,5 pulg. La imagen de un perro obtenida con el colimador de 6,5 pulg en una exploracion efectuada con oro-198 mostro muy bien una concentracion de actividad de un diametro aparentemente de menos de 0,25 pulg (6 mm); la actividad era solo cinco veces mayor que el 'fondo corporal', pero quedaba claramente separada por 0,25 pulg de una fuente de 0,75 pulg de diametro unas 50 veces mas intensa. (author) [Russian] Osnovnaja prichina ispol'zovanija ''fokusirujushhego kollimatora'' svoditsja k t om u , chtoby pozvolit' ispol'zovat' krupnyj d et ek t or , dajushhij povyshennuju skorost' scheta b e z poteri prostranstvennoj razreshajushhej sp o so bn o s ti . Poskol'ku ispol'zuetsja neskol'ko apertur, napravlennyh na odnu obshhuju tochku, dosti ga et sja horoshij ''okusirujushhij'' jeffekt. Vvidu neobhodimosti imet' tonkuju peregorodku mezhdu aperturami, proniknovenie skvoz' jeti stenki gamma-luchej vyzyvaet poterju prostranstvennogo razreshenija. Byli ispol'zovany vol'fram i zoloto (dlja detektorov diametrom 7,5 sm) dlja togo, chtoby umen'shit' jeto , chto dalo vozmozhnost' provesti proniknovenie po sravneniju s t em , kogda primenjaetsja svinec. Umen'shenie proniknovenija za schet primenenija udlinennogo svincovogo kollimatora nanosit ushherb osnovnym konstrukcionnym celjam iz - z a uvelichenija skorosti sch et a , esli ne ispol'zuetsja takzhe krupnyj det ek tor. Avtory sproektirovali i sozdali svincovyj kollimator s 91 otverstiem dlja ispol'zovanija s d et ektorom NaJ (T 1 ) r a zm er om 13,5 h 7,5 s m . Fokus nahoditsja na rasstojanii 24 sm ot d et ek tora , a prostranstvennyj ugol vosprijatija analogichen uglam fokusirujushhih kollimatorov pri odnovremennom ispol'zovanii ih s detektorami na 7,5 sm . Maksimal'naja dlina sostavlja et 16,5 sm ; obychnaja dlina konstrukcii sost avlja et 14 sm . Pri dannyh velichinah dliny opticheskie ''okruzhnosti razreshenija'' sostavljajut sootvetstvenno 1,2 i 0,77 sm . Jeti konstrukcii dajut sledujushhee: 1 . Bol e e dlinnoe fokusnoe r a s stojan i e s odn o vremennym uvelicheniem jeffektivnosti scheta blagodarja b ol e e krupnomu ljuminoforu. 2 . Svincovyj kollimator s razreshajushhej sposobnost'ju, kotoruju mozhno sravnit' s bolee korotkimi kollimatorami iz zolot a (skennogramma t ochechnogo istochnika C s-V a 137 imeet di ametr v sego 7 m m ) . 3. Kollimator s vysokoj stepen'ju razreshenija dlja skennirovanija chelovecheskogo organizma i melkih zhivotnyh. 4. Osnovnaja konstrukcija sborki dlja ispol'zovanija kollimatorov s bolee krupnym prostranstvennym uglom dlja uvelichenija jeffektivnosti scheta. Polucheny skennogrammy v sego organizma s primeneniem zolota -198 i jod a -131. Obnaruzhena vozrosshaja jeffektivnost' i razreshenie 14-sm kollimatora. Na skennogramme sobaki s 16,5 sm kollimatorom horosho vidna koncentracija aktivnosti, imejushhaja, ochevidno, v Diametre menee 6m m; aktivnost',lish' v 5 raz prevyshajushhaja ''fon organizma'', vse zhe byla chetko otdelena rasstojaniem 6 mm ot istochnika diametrom 1,8 sm s bolee vysokim (v 50 raz) urovnem aktivnosti. (author)

  2. Report on the survey of the project on the environmentally friendly type energy community field test. Separate volume - reference data. Investigative project for development and commercialization of recycle technology of waste edible oil; 2001 nendo kankyo chowa gata energy community field test jigyo chosa hokokusho. Hai shokuryo yu no recycle gijutsu kaihatsu to jitsuyoka no tameno chosa jigyo (Bessatsu - Sanko shiryo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-06-01

    For the purpose of promoting the effective utilization of biomass resource, an investigative study was made on the development of recycle technology of waste edible oil. In the survey, the following were carried out and the results were summarized: promotion measures for biodiesel oil by the EU, promotion measures for biodiesel oil by other countries including Canada, promotion measures for biodiesel oil by the US's Department of Energy (DOC), actual results of the use of biodiesel oil in Kyoto City, reference data on biodiesel oil in Japan, and tackling toward the promotion of BDF in the Ministry of Agriculture, Forestry and Fisheries. As to the transportation use fuel in the EU in the coming 20 years, biofuel, natural gas and hydrogen seem to be selected. If measures are positively taken, biofuel is expected to be 2%, 6%, 7% and 8% in FY 2005, FY 2010, FY 2015 and FY 2020, respectively. Also, natural gas is expected to be 2% in FY 2010, 5% in FY 2015 and 10% in FY 2020, and hydrogen is expected to be 2% in FY 2015 and 5% in FY 2020. (NEDO)

  3. 16-channel analyser with high time-resolution for multiple coincidence experiments; Selecteur a 16 canaux a temps de resolution eleve pour experiences de coincidences multiples; Ispol'zovanie shestiadtsatikanal'nogo analizatora s bol'shoj razreshayushchej sposobnost'yu po vremeni dlya opytov s mnogokratnymi sovpadeniyami; Analizador de 16 canales de elevado poder temporal de resolucion para experimentos de coincidencias multiples

    Energy Technology Data Exchange (ETDEWEB)

    Brandt, B; Cappeller, U [University of Marburg, Marburg, Federal Republic of Germany (Germany)

    1962-04-15

    In usual slow-fast-coincidence experiments such events are counted which are selected in pulse-height by means of single-channel analysers. It is desirable to extend these techniques to a simultaneous energy-analysis of the pulses, selecting pulse-heights by means of multi-channel analysers. Multi-channel analysers used to perform such multiple coincidence experiments should give information about the amplitudes of arriving pulses at a well defined time-interval after the rising of the analysed pulse. A 16-channel pulse-height analyser is described which permits the generation of a pulse-height signal 2.5 x 10{sup -6} s after pulse-rising with an uncertainty of less than {+-} 2 x 10{sup -8} s. The resolving-time is less than 5 x 10{sup -6} s, controlled by an inspector-circuit to avoid distortions arising from the pile-up of pulses. The channel width is controlled by a window-amplifier, adjustable from 1 V to 7 V. The channel-height may be selected from 7 V to 103 V in steps of 0.5 V. (author) [French] En general, dans les experiences de coincidences lentes-rapides, on compte des evenements traduits sous forme d'impulsions dont l'amplitude est selectionnee a l'aide de selecteurs a un seul canal. Il est souhaitable d'etendre cette technique a l'analyse simultanee de l'energie des impulsions, en selectionnant les amplitudes au moyen de selecteurs a canaux multiples. Les selecteurs multi-canaux utilises pour ces experiences de coincidences multiples devraient fournir une indication sur les amplitudes des impulsions d'entree a un intervalle de temps bien defini, apres la montee de l'impulsion analysee. Les auteurs decrivent un selecteur d'amplitude a 16 canaux, qui delivre un signal 2,5 {center_dot} 10{sup -6} s apres l'etablissement de l'impulsion avec une erreur inferieure a {+-} 2 {center_dot} 10{sup -8} s. Le temps de resolution, inferieur a 5 {center_dot} 10{sup -6} s, est commande par un circuit special pour eviter les derangements qui resulteraient de l'empilement des impulsions. La largeur du canal est commandee par un amplificateur a fenetre, ajustable entre 1 V et 7 V. La hauteur du canal peut etre reglee entre 7 V et 103 V, de 0,5 V en 0,5 V. (author) [Spanish] En los experimentos de coincidencia lenta-rapida se cuentan generalmente sucesos cuya amplitud de impulso ha sido seleccionada por medio de analizadores de un solo canal. Resulta conveniente lograr que estas tecnicas permitan analizar simultaneamente las energias de varios impulsos, seleccionando sus amplitudes por medio de analizadores de canales multiples. Los analizadores que se emplean en los experimentos de coincidencia multiple deben informar sobre las amplitudes de los impulsos incidentes (ordenandolos en canales de amplitud) tras un intervalo de tiempo bien definido despues de establecido el impulso que se analiza. Se describe un analizador de amplitudes de impulso de 16 canales que permite generar una senal de amplitud de impulso 2,5 x 10{sup -6} s despues de establecido este, con un error inferior a 2 x 10{sup -8} s. El tiempo de resolucion es menor de 5 x 10{sup -6} s y esta controlado por un circuito inspector para evitar distorsiones debidas a la acumulacion de impulsos. La anchura del canal, controlada por un amplificador de ventana, es ajustable entre 1 y 7 V. La posicion del canal puede variarse entre 7 y 103 V a intervalos de 0,5 V. (author) [Russian] Pri obychnykh opytakh s medlennymi i bystrymi sovpadeniyami proizvoditsya otschet velichin, kotorye vybirayutsya po amplitude impul'sov pri pomoshchi odnokanal'nykh analizatorov. Predstavlyaetsya zhelatel'nym rasprostranit' ehti metody na odnovremennyj analiz ehnergii impul'sov, putem otbora impul'sov po amplitude pri pomoshchi mnogokanal'nykh analizatorov. Mnogokanal'nye analizatory, primenyaemye dlya proizvodstva takogo roda opytov s mnogokratnymi sovpadeniyami, dolzhny davat' svedeniya otnositel'no amplitudy postupayushchikh impul'sov (raspredelyaya ikh po amplitudnym kanalam) v tochno opredelennye promezhutki vremeni posle narastaniya issleduemogo impul'sa. Opisyvaetsya shestikanal'nyj amplitudnyj analizator impul'sov, pozvolyayushchij proizvodit' signaly amplitudy impul'sa cherez 2,5 x 10{sup -6} sekundy posle narastaniya impul'sa s predelom pogreshnosti menee, chem {+-} 2 x 10{sup -8} sekundy. Vremya razresheniya ne prevyshaet 5 x 10{sup -6} sekund; vo izbezhanie iskazheniya v rezul'tate nakopleniya impul'sov ehto vremya reguliruetsya kontrol'nym konturom. SHirina kanala reguliruetsya usilitelem s oknom, kotoryj mozhet regulirovat'sya v intervale ot 1 v do 7 v. Vysota kanala mozhet vybirat'sya cherez kazhdye 0,5 v v intervale ot 7 v do 103 v. (author)

  4. Report on the survey of the project on the environmentally friendly type energy community field test. Investigative project for development and commercialization of recycle technology of waste edible oil; 2001 nendo kankyo chowa gata energy community field test jigyo chosa hokokusho. Hai shokuryo yu no recycle gijutsu kaihatsu to jitsuyoka no tameno chosa jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-06-01

    An investigative study was made of the use of waste edible oil as fuel and recycle use of residual food in the food service business. As to the existence/recovery of edible oil, it was found out that waste edible oil of 15.9g/meal per capita was discharged at multiple wide-area distributed shops and that the total amount reached 1,861kl/y in the country. Concerning the technology for using it as biodiesel fuel, Ronford Co., which has the most actual results of the technology, recovers waste edible oil in Kyoto City, refines it and uses it as fuel for the City's garbage truck. About the use of waste edible oil as boiler use fuel, there are examples in Sapporo Grand Hotel, which has been contributing to energy conservation for more than five years. In the assessment of the profitability as project, for the direct combustion for boiler fuel use, the same/large heat supply system is a prerequisite, and for the hot stove loaded type direct combustion, there is an element of the technology development. Therefore, the use as bio-diesel fuel is most expected, though there is a taxation problem. (NEDO)

  5. Study on Restriction Contract in Huizhou during Qing Dynasty-48 Pieces of Restriction Contract in Huizhou of Yu Jiang's Collection%论清代徽州禁约合同--以俞藏48件徽州禁约文书为中心

    Institute of Scientific and Technical Information of China (English)

    陈云朝; 童旭

    2014-01-01

    Restriction contract is a kind of contract documents in which the clansmen and fellow villagers covenant and negotiate penalty provisions to prohibit stealing and chopping trees,protecting Lailong, Shuikou and other affairs.It has a broad application scope and diverse types;meanwhile the main contrac-ting body is generally a clan,an association or a union of people with different surnames.The contents trend to embody compulsory regulations on prohibition and punishment.The validity of restriction contract is guaranteed by self protection or “submitting to the government for treatment.”As the necessary comple-ment and extension of the national law,it plays an important role in the construction of the basic social or-ders.%禁约合同是同族、同村人等为禁止盗窃、砍伐树木、保护来龙与水口等事务,共同立约承诺并议定罚则的合同文书。其适用领域广泛,类型多样,订立主体多为宗族、会社以及数姓的联合;内容上更多地体现为禁止、惩罚等强制性规范。对违禁行为进行私力救济或“呈官究治”,保证了禁约合同效力的实施。作为国家法的必要补充和延伸,禁约合同在基层社会秩序的构建中扮演了十分重要的角色。

  6. Compilation of the ``Atlas of Gamma-rays from the Inelastic Scattering of Reactor Fast Neutrons'' (1978DE41) by A.M. Demidov, L.I. Govor, Yu. K. Cherepantsev, M.R. Ahmed, S. Al-Najjar, M.A. Al-Amili, N. Al-Assafi, and N. Rammo

    Energy Technology Data Exchange (ETDEWEB)

    Hurst, Aaron M. [Univ. of California, Berkeley, CA (United States); Bernstein, Lee A. [Univ. of California, Berkeley, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Chong, Su-Ann [Univ. of California, Berkeley, CA (United States)

    2017-07-26

    A Structured Query Language (SQL) relational database has been developed based on the original (n,n'gamma) work carried out by A.M. Demidov et al., at the Nuclear Research Institute in Baghdad, Iraq [``Atlas of Gamma-Ray Spectra from the Inelastic Scattering of Reactor Fast Neutrons'', Nuclear Research Institute, Baghdad, Iraq (Moscow, Atomizdat 1978)] for 105 independent measurements comprising 76 elemental samples of natural composition and 29 isotopically-enriched samples. The information from this ATLAS includes: gamma-ray energies and intensities; nuclide and level data corresponding to where the gamma-ray originated from; target (sample) experimental-measurement data. Taken together, this information allows for the extraction of the flux-weighted (n,n'gamma) cross sections for a given transition relative to a defined value. Currently, we are using the fast-neutron flux-weighted partial gamma-ray cross section from ENDF/B-VII.1 for the production of the 847-keV transition from the first excited 2+ state to the 0+ ground state in 56Fe, 468 mb. This value also takes into account contributions to the 847-keV transition following beta(-) decay of 56Mn formed in the 56Fe(n,p) reaction. However, this value can easily be adjusted to accommodate the user preference. The (n,n'gamma) data has been compiled into a series of ASCII comma separated value tables and a suite of Python scripts and C modules are provided to build the database. Upon building, the database can then be interacted with directly via the SQLite engine or accessed via the Jupyter Notebook Python-browser interface. Several examples exploiting these utilities are also provided with the complete software package.

  7. Scanning Study of 700 Livers Evaluation of Existing Diagnostic Procedures; Etude Scintigraphique de 700 Foies (Evaluation des Procedures Actuelles de Diagnostic); Issledovanie pecheni 700 bol'nykh s pomoshch'yu skennirovaniya; Exploracion Hepatica de 700 Pacientes (Evaluacion de los Metodos Actuales De Diagnostico); Exploracion Hepatica de 700 Pacientes (Evaluacion de los Metodos Actuales de Diagnostico)

    Energy Technology Data Exchange (ETDEWEB)

    Czerniak, P. [Radium and Isotope Institute, Government Hospital, Tel-Hashomer (Israel)

    1964-10-15

    The livers of 700 patients have been examined. Clinical studies, laboratory tests, roentgenographic examinations and liver-scanning studies were performed. The patients were followed up and finally an objective diagnostic confirmation was obtained in most cases. In this way an evaluation of the performed tests was established. The liver scanning was done using Au{sup 198}, I{sup 131}-Rose Bengal and I{sup 131} PVP. Apart from the classical AP technique, special techniques were utilized, such as tri- or bi-plane stereoscanning and combined isotope studies with Au{sup 198} and I{sup 131}-Rose Bengal leading to a determination of the RLC (radioisotope liver coefficients). The patients were divided into eight clinical groups and the diagnostic data were accordingly compiled and evaluated. A summary of the results of this study is presented. Each clinical group was separately analysed. For example, a space-occupying lesion was detected in 95% of the 65 cases of Echinococcus disease. X-ray examination detected calcifications in only 35% of these cases, but also in 14% of other liver diseases. Weinberg and Casoni reactions were positive in 64% of the cases of Echinococcus, but also in 22% of other diseases. In hepatic malignancy, a space-occupying lesion was detected in 44% of cases, a foggy scan in 30% and morphological changes in 29%. In two of the 158 tumour cases the scan falsely appeared to be normal, but in 40% of the same cases the laboratory results were negative. By using the bi- and tri-plane stereoscanning technique, new and supplementary information on the state of the liver was obtained in 45% of cases. Liver scanning was also used in the follow-up study. It was found that: (1) After Echinococcotomy, a definite scar persists as a space-occupying lesion; (2) Three months after a treated amoebic abscess, complete regeneration occurs; (3) After a porto-caval shunt, the liver scan becomes smaller and the spleen larger - even when the general condition is satisfactory; (4) Cytostatic agents may be temporarily effective in some diffuse hepatic lesions; (5) A rescanned suspected lesion may reappear as a space-occupying lesion or disappear. Thus the time of scanning may affect the diagnosis. Conclusions: (1) Liver scanning can be considered as a very useful method for clinical, morphological and topographical diagnosis in hepatopathology; and (2) The results may be improved by (a) advanced instrumentation and the use of stereoscanning techniques and (b) good collaboration between the internists and surgeons. (author) [French] On a examine les foies de 700 malades (etude clinique, analyses en laboratoire, examens radiographiques, explorations scintigraphiques). Onacontinuea les malades apres ces examens; on a pu avoir la confirmation objective du diagnostic dans la plupart des cas et evaluer les resultats de la campagne. Pour la scintigraphie du foie, on a utilise l'or-198, le rose bengale marque avec {sup 131}I et le polyvinylpyrrolidone egalement marque avec {sup 131}I. On a applique, non seulement la methode classique, mais aussi des methodes particulieres comme l'exploration stereographique dans deux plans ou trois plans et l'emploi combine de l'or-198 et du rose bengale marque a l'iode-131 pour determiner les coefficients relatifs de fixation de ces radioisotopes dans le foie. Les sujets avaient ete repartis en huit groupes cliniques aux fins de compilation et devaluation des resultats du diagnostic, qui sont presentes succinctement dans le memoire. Chaque groupe clinique a ete analyse separement. Par exemple, on a detecte une lesion en volume dans 95% des 65 cas d'echinococcose. La radiographie a permis de constater des calcifications dans 35% seulement de ces cas, mais aussi dans 14% des autres cas de maladies hepatiques. Les reactions de Weinberg et Casoni ont ete positives dans 64% des cas d'echinococcose, mais aussi dans 22% des autres cas. En ce qui concerne le cancer du foie, on a detecte une lesion en volume dans 44% des cas, on a obtenu un scintigramme voile dans 30% des cas et on a constate des modifications morphologiques de l'organe dans 29% de cas. Dans deux des 158 cas de tumeurs malignes, le scintigramme semblait faussement normal, mais dans 40% de ces memes cas les resultats obtenus au laboratoire etaient negatifs. Par la technique d'exploration stereographique dans deux ou trois plans, on a obtenu dans 45% des cas des renseignements nouveaux ou complementaires sur l'etat de l'organe. On a egalement utilise la scintigraphie pour le controle ulterieur des resultats. On a fait les constations suivantes: 1. Apres extirpation du kyste hydatique, une cicatrice caracterisee persiste sous forme de lesion en volume; 2. Trois mois apres le traitement d'un abces amibien, une regeneration complete intervient; 3. Apres une derivation porto-cavale, le scintigramme du foie devient plus petit et celui de la rate plus grand - meme lorsque l'etat general est satisfaisant; 4. Les agents cytostatiques peuvent etre momentanement efficaces pour certaines lesions hepatiques diffuses; 5. Il arrive qu'une lesion dont on n'avait pu affirmer la presence avec certitude devienne macroscopique ou qu'elle cesse totalement d'etre visible; par consequent, le moment de l'exploration peut affecter le diagnostic. L'auteur tire les conclusions suivantes: 1. On peut considerer la scintigraphie comme une methode tres utile pour le diagnostic clinique, morphologique et topographique en hepatopathologie. 2. On peut ameliorer les resultats: a) en utilisant des appareils perfectionnes ou en ayant recours aux techniques d'exploration stereographiques; b) par une bonne collaboration entre le clinicien et le chirurgien. (author) [Spanish] El autor ha examinado el higado de 700 pacientes (estudios clinicos, analisis de laboratorio, examenes roentgenograficos y exploraciones centelleograficas), ha seguido la evolucion clinica de los pacientes y ha podido obtener en la mayoria de los casos una confirmacion objetiva del diagnostico. Esto ha permitido evaluar los ensayos realizados. Para la exploracion del higado se utilizo 198Au, Rosa Bengala marcado con {sup 131}I y polivinilpirrolidona marcada tambien con {sup 131}I. Ademas de la exploracion anteroposterior, se recurrio a tecnicas especiales como la exploracion estereoscopica en dos o tres planos y al empleo combinado del {sup 198}Au y el Rosa Bengala marcado con {sup 131}I para determinar los coeficientes relativos de fijacion de estos radioisotopos en el hfgado. Los pacientes habfan sido distribuidos en ocho grupos clinicos con miras a la compilacion y evaluacion de los resultados del diagnostico. En la memoria se presenta un resumen de estos resultados. Cada grupo clfnico se analizo por separado. Por ejemplo, se detecto una lesion macroscopica en el 95% de los 65 casos de equinococosis. La radiografia solo permitio descubrir calcificaciones en el 35% de estos casos, pero tambien en el 14% de los otros casos de afecciones hepaticas. Las reacciones de Weinberg y Casoni fueron positivas en el 64% de los casos de equinococosis, pero tambien en el 22 por ciento de las otras enfermedades. En loque respecta al cancer del hfgado, se detecto una lesion macroscopica en el 44% de los casos, se obtuvo un centelleograma velado en el 30% y se observaron modificaciones morfologicas en el 29%. En dos de los 158 casos de tumores malignos, el centelleograma parecia falsamente normal, pero en el 40% de estos mismos casos los resultados obtenidos en el laboratorio fueron negativos. Con la tecnica de exploracion estereoscopica en dos o tres planos se obtuvieron datos nuevos o complementarios sobre el estado del higado en el 45% de los casos. La centelleografia se utilizo tambien para el control ulterior de los resultados. Se han hecho las siguientes observaciones: 1. Despues de una equinococotomia persiste una cicatriz caracteristica en forma de lesion macroscopica. 2. Tres meses despues del tratamiento de un absceso amebico, se produce una regeneracion completa. 3. Despues de una derivacion porta-cava, la imagen del higado es mas pequena y la del bazo mas grande, incluso cuando el estado general es satisfactorio. 4. Los agentes citostaticos pueden ser momentaneamente eficaces para ciertas lesiones hepaticas difusas. 5. Ha ocurrido a veces que al explorar de nuevo una lesion dudosa esta ha aparecido como una lesion macroscopica o ha desaparecido totalmente. Por tanto, la epoca en que se efectua la exploracion puede afectar al diagnostico, . Conclusiones: 1. La exploracion hepatica puede considerarse como metodo muy util para el diagnostico clfnico, morfologico y topografico en hepatopatologia. 2. Los resultados pueden mejorarse: a) utilizando aparatos perfeccionados o tecnicas de exploracion estereoscopica, y b) estableciendo una eficaz colaboracion entre el clinico y el cirujano. (author) [Russian] Provodilis' klinicheskie issledovanija, laboratornye analizy, rentgenograficheskoe obsledovanie i skennirovanie pecheni 700 bol'nyh. Za bol'nymi bylo ustanovleno nabljudenie, i v bol'shinstve sluchaev v konechnom itoge diagnoz podtverdilsja. Takim obrazom byla dana ocenka provedennym issledovanijam. Skennirovanie pecheni proizvodilos' s pomoshh'ju bengal'skoj rozy i polivinilpirolidona, mechennyh zolotom-198 i jodom-131 . Pomimo klassicheskogo AR-metoda dlja opredelenija ra- dioizotopnyh kojefficientov pecheni primenjalis' special'nye metody, takie kak treh ili dvuhploskostnoe stereoskennirovanie i kombinirovannoe izotopnoe issledovanie s pomoshh'ju mechennoj zolotom-198 i jodom-131 bengal'skoj rozy. Bol'nye byli razdeleny na vosem' klinicheskih grupp, i sootvetstvenno proizvodilsja sbor i ocenka diagnosticheskih dannyh. Daetsja kratkoe izlozhenie rezul'tatov jetogo issledovanija. V kazhdoj klinicheskoj gruppe analizy provodilis' otdel'no. Naprimer, v 95%iz 65 sluchaev jehinokokkovoj bolezni byl obnaruzhen ogranichennyj uchastok porazhenija. Rentgenovskoe obsledovanie vyjavilo obizvestvlenie tol'ko v 35%jetih sluchaev, a takzhe v 14% sluchaev drugih zabolevanij pecheni. Reakcii Vajnberga i Kasoni byli polozhitel'ny v 64% sluchaev jehinokokkovoj bolezni, a takzhe v 22%sluchaev drugih zabolevanij. Pri zlokachestvennyh zabolevanijah pecheni ogranichennyj uchastok porazhenija byl obnaruzhen v 44% sluchaev, nejasnaja skennogramma v 30%, morfologicheskie izmenenija -v*29%. V dvuh iz 158 sluchaev skennogramma oshibochno okazalas' normal'noj, odnako v 40% jetih zhe sluchaev laboratornye rezul'taty byli otricatel'nymi. Blagodarja primeneniju metoda dvuh i trehploskostnogo stereoskennirovanija v 45% sluchaev byli polucheny novye i dopolnitel'nye dannye o sostojanii pecheni. Skennirovanie pecheni primenjalos' takzhe pri posledujushhih issledovanijah. Bylo obnaruzheno, chto: 1) posle jehinokokkotomii ostaetsja otchetlivyj rubec kak ogranichennyj uchastok porazhenija; 2) cherez tri mesjaca posle izlechenija amebnogo abscessa proishodit polnaja regeneracija; 3) posle sozdanija porto-kaval'nogo anastomoza razmer skennogrammy pecheni umen'shaetsja , a selezenki -uvelichivaetsja, dazhe pri udovletvoritel'nom obshhem sostojanii; 4) pri nekotoryh diffuznyh porazhenijah pecheni citostaticheskie agenty mogut byt' vremenno jeffektivny; 5) pri povtornom skennirovanii predpolagaemoe zabolevanie mozhet okazat'sja ogranichennym uchastkom porazhenija ili ischeznut'. Takim obrazom diagnoz zavisit ot vremeni skennirovanija. Vyvody: 1. Skennirovanie pecheni mozhet schitat'sja ochen' poleznym metodom klinicheskogo, morfologicheskogo i topograficheskogo diagnoza pri patologicheskih izmenenijah pecheni. 2. Rezul'taty mogut byt' uluchsheny putem: a) uluchshenija apparatury i primenenija metodov stereoskennirovanija, b) luchshego sotrudnichestva mezhdu terapevtami i hirurgami. (author)

  8. Autofluorography with an X-Ray Image Amplifier; Autofluorographie a l'Aide d'un Amplificateur d'Images a Rayons X; Avtofl u orografiya s pomoshch'yu usilitelya rentgenovskogo izobrazheniya; Autofluorografia con un Amplificador de Imagen de Rayos X

    Energy Technology Data Exchange (ETDEWEB)

    Ter-Pogossian, M. M.; Eichling, J. O. [Washington University School of Medicine, St. Louis, MO (United States)

    1964-10-15

    The visualization of organs containing radioactive isotopes emitting X- or gamma-ray photons with energies between 20 and about 100 keV can be achieved by converting the radiation emerging from the organ into light by means of an X-ray image amplifier of conventional design. The apparatus designed for this purpose consists of the following elements: (1) A collimator, the specifications of which are determined by the resolution and by the operating distance desired. (2) An electrostatic focusing X-ray image amplifier, which converts the collimated X- or gamma-ray photons into an optical image of high brightness. (3) A large aperture lens system which projects the image into: (4) A ''Polaroid'' camera loaded with fast (10 000 ASA), high-contrast film. The performance of this apparatus for low-energy photons is superior to that of conventional scintiscanners. The usefulness of this apparatus for the visualization of brain tumours and kidneys and the thyroid gland is discussed. (author) [French] Pour permettre la visualisation d'organes contenant des radioisotopes emetteurs de rayons X ou gamma ayant une energie de 20 a 100 keV, on peut convertir en lumiere le rayonnement provenant de l'organe examine au moyen d'un amplificateur d'images a rayons X du type classique. Le dispositif concu a cet effet comprend les elements suivants: 1. Un collimateur dont les caracteristiques sont determinees par la resolution et la distance source-detecteur souhaitables; 2. Un amplificateur d'images a rayons X, electrostatique et focalisant, qui transforme les rayons X ou gamma collimates en une image optique de forte luminosite; 3. Un ensemble de lentilles a grand angle d'ouverture, qui projette l'image dans l'appareil photographique ci-dessous; 4. Un appareil photographique 'Polaroid' charge d'un film rapide (10 000 ASA) a fort contraste. Les performances de ce dispositif en presence de photons de faible energie sont superieures a celles des scintigraphes classiques. Les auteurs traitent de l'utilite de ce dispositif pour la visualisation des tumeurs du cerveau, des reins et de la thyroide. (author) [Spanish] La visualizacion de organos que contienen isotopos radiactivos emisores de fotones (rayos X o gamma) de energia comprendida entre 20 y 100 keV aproximadamente, puede lograrse convirtiendo en luz, mediante un amplificador de imagen de rayos X de tipo corriente, la radiacion emitida por el organo. El aparato construido con esta finalidad esta constituido por los siguientes elementos: 1. Un colimador, cuyas caracteristicas vienen determinadas por el poder de resolucion y la distancia a que debe operar. 2. Un amplificador de imagen de rayos X de enfoque electrostatico, que convierte los rayos X o gamma colimados en una imagen optica muy brillante. 3. Un sistema de lentes de gran apertura que proyecta la imagen en la camara mencionada a continuacion. 4. Una camara 'Polaroid' cargada con pelicula rapida (10 000 ASA) de gran contraste. El rendimiento de este aparato para fotones de baja energia es superior al de los exploradores centelleograficos de tipo tradicional. Los autores examinan su utilidad para visualizar tumores cerebrales, renales y tiroideos. (author) [Russian] Vizual'noe nabljudenie organov, soderzhashhih radioaktivnye izotopy, kotorye i z luchajut rentgenovskie kvanty ili gamma-kvanty s jenergijami v predelah ot 20 do 100 kjev, do stiga et sja za schet prevrashhenija radiacii organa v svechenie s pomoshh'ju usilitelja rentgenovskogo izobrazhenija obychnogo tipa. Skonstruirovannyj dlja jetoj celi apparat sostoit iz sledujushhih jelementov: 1 . Kollimatora, harakteristiki kotorogo opredeljajutsja razreshajushhej sposobnost'ju i zh e laemym rabochim rasstojaniem. 2 . Jelektrostaticheskogo fokusirujushhego usilitelja r ent genov skogo izobrazhenija, kotoryj prevrashhaet kollimirovannye rentgenovskie kvanty ili gamma-kvanty v opticheskoe izobrazhenie, imejushhee bol'shuju jarkost'. 3 . Ob{sup e}ktiva s bol'shoj diafragmoj, kotoryj proeciruet izobrazhenie na kameru. 4 . Kamera ''Polaroid'', zarjazhennaja vysokochuvstvitel'noj (10.000 ASA) plenkoj s vysokoj kontrastnost'ju. Po kachestvam raboty s fotonami maloj jenergii jetot apparat luchshe, chem obychnye scinti- skennery. i Obsuzhdaetsja prigodnost' jet ogo apparata dlja vizual'nogo nabljudenija opuholej mozga pochek i shhitovidnoj zhelezy . (author)

  9. Contrast Enhancement by Multicolour Print-Out of Thyroid, Kidney, Liver and Brain Scans; Accentuation des Contrastes dans les Scintigrammes Polychromes du Cerveau, du Foie, du Rein et de la Thyroide; Kontrastnoe usilenie s pomoshch'yu mnogotsvetnogo otpechatka skennogramm shchitovidnoj zhelezy, pochek, pecheni i golovnogo mozga; Aumento del Contraste en los Centelleogramas Policromos de la Tiroides, el Rinon, el Higado y el Cerebro

    Energy Technology Data Exchange (ETDEWEB)

    Hine, G. J.; Patten, D. H.; Burrows, B. A. [Radioisotope Service, Veterans Administration Hospital Boston University School of Medicine Boston, MA (United States)

    1964-10-15

    Quantitative information can be obtained from a scan if the colour of the print-out changes with the count-rate. The printing pattern shows then the radioisotope distribution and the printing colour serves as a code for a digital evaluation of the scan. This can delineate areas with small differences in count-rate more clearly than other read-out methods. A stylus hits one of several coloured typewriter ribbons mounted on a common carriage. Its movement is controlled by a count-rate meter with a time constant of 0.3 s. The first ribbon covering the lowest countrate interval is uninked. This suppresses coloured prints at count-rates of less than 12.5% of the 100% maximum adjusted for each scan when eight coloured ribbons are used. However, all counts are preserved in black on carbon copies. The clinical advantage of the colour scan is to recognize immediately differences in count-rate which outline areas of varying radioisotope concentration. The colour cut-off at low count-rates yields an improved visualization of areas such as brain lesions, which are difficult to localize due to high tissue background. The colour scan outlines the contours corresponding to the thickness of functioning liver tissue which are not easily seen otherwise. Compared with normal liver scans, areas of fibrosis and tumour infiltration are more readily recognized. The same is true for kidney scans where a change in colour may indicate ischemic, cystic or tumour areas. For thyroid scans, the colour print-out provides semi-quantitative comparison of radioiodine uptake in different areas. (author) [French] Un scintigramme peut fournir des renseignements quantitatifs si la couleur de l'epreuve photographique varie suivant le taux de comptage. Le dessin de l'epreuve indique alors comment se repartit le radioisotope, et sa coloration est utilisee comme code pour l'evaluation numerique du scintigramme. Cette technique permet de determiner, plus clairement que d'autres methodes de lecture, le contour de zones ou les differences de taux de comptage sont faibles. Des rubans de machines a ecrire de diverses couleurs sont montes sur un chariot unique; un stylet, dont le mouvement est commande par un debitmetre, avec une constante de temps de 0 ,3 s, frappe l'un des rubans. Le premier ruban, qui correspond a la gamme des taux de comptage la plus basse, n'est pas encre; ainsi, il n'y a pas de marques colorees pour les taux de comptage inferieurs a 12, 5% du maximum, qui est ajuste pour chaque scintigramme lorsque les huit rubans colores sont utilises en meme temps. Toutefois, tous les coups sont enregistres en noir sur des copies carbone. Du point de vue clinique, le scintigramme polychrome a l'avantage de faire apparaitre immediatement les differences de taux de comptage qui delimitent des zones oue la concentration du radioisotope n'est pas la meme. La suppression de la couleur, pour les taux de comptage peu eleves, permet de mieux distinguer certaines zones difficiles a localiser par suite de l'intensite du bruit de fond du aux tissus, par exemple les lesions cerebrales. Le scintigramme polychrome fait apparaitre les contours correspondant a l'epaisseur du tissu hepatique qui participe aux fonctions du foie et qu'il est difficile de voir autrement. Il permet d'identifier plus aisement les zones de fibrose et d'infiltration neoplasique, en le comparant avec des scintigrammes de foies normaux. Il en est de meme pour des scintigrammes de reins, oiei une modification de la couleur peut indiquer la presence de zones ischemiques, cystiques ou tumorales. Le scintigramme polvchrome de la thyroiede permet de proceder a des comparaisons semi-quantitatives de la fixation du radioiode entre les differentes zones. (author) [Spanish] Un centelleograma puede proporcionar datos cuantitativos si el color de la impresion varia segun el indice de recuento. La estructura de la impresion indica entonces la reparticion de los radioisotopos; su color sirve de clave para la evaluacion numerica del centelleograma. Esta tecnica permite delimitar mas claramente que otros metodos de lectura las zonas en que las diferencias del indice de recuento son muy reducidas. En un mismo carro se montan cintas de maquina de escribir de diferentes colores; un punzon, cuyo movimiento esta regido por un integrador, con una constante de tiempo de 0,3 s, golpea una de las cintas. La primera, que corresponde al intervalo mas bajo del indice de recuento, no tiene tinta; asi, no hay senales en color para los indices de recuento inferiores al 12,5 por ciento del valor maximo, que se ajusta para cada centelleograma cuando se utilizan las ocho cintas de color. Sin embargo, todos los impulsos quedan registrados en copias sacadas con papel carbon. Desde el punto de vista clinico, el centelleograma policromo tiene la ventaja de que hace aparecer inmediatamente las variaciones del indice de recuento que delimitan zonas con concentraciones de radioisotopos distintas. La supresion del color para los indices de recuento poco elevados permite distinguir mejor ciertas zonas que son dificiles de visualizar a consecuencia de la intensidad de la actividad de fondo debida a los tejidos, por ejemplo, las correspondientes a lesiones cerebrales. Los centelleogramas policromos hacen aparecer los contornos correspondientes al espesor del tejido hepatico que participa en las funciones del higado y que dificilmente pueden observarse de otra manera. Permiten identificar mejor las zonas de fibrosis y de infiltracion tumoral comparandolos con centelleogramas de tipo corriente. Lo mismo puede decirse de los centelleogramas del rinon en los que un cambio de color puede indicar la presencia de zonas isquemicas, cisticas o tumorales. Los centelleogramas policromos de la tiroides permiten proceder a una comparacion semicuantitativa de la concentracion del yodo radiactivo en las diferentes zonas. (author) [Russian] S pomoshh'ju skennogrammy mozhno poluchit' kolichestvennuju informaciju, esli cvet snimka i zm e njaetsja vmeste s intensivnost'ju scheta. Obrazcy snimkov pokazyvajut raspredelenie radioizotopov, a cvetnye otpechatki sluzhat v kachestve koda dlja cifrovoj ocenki skennogrammy. Jeto da et vozmozhnost' ustanovit' ochertanija uchastkov s nebol'shimi rashozhdenijami v sk o rosti scheta gor a zd o luchshe, chem pri drugih metodah snjatija pokazanij. Pero ostavljaet sled na odnoj iz neskol'kih cvetnyh lent pishushhej mashinki, smontirovannyh na obshhej k ar etk e. Ego dvizhenija kontrolirujutsja izmeriteljami skorosti scheta s postojannoj vremeni v 0,3 sekundy. Na pervuju lentu, sootvetstvujushhuju samoj nizkoj skorosti scheta , chernila ne n anosjatsja. Jeto iskljuchaet cvetnoj otpechatok pri skorosti scheta men'shej 12,5%ot maksimuma v 100%dlja kazhdoj skennogrammy, so otvetstv ujushh e go ispol'zovaniju 8 cvetnyh l en t . Odnako, v sevychislenija sohranjajutsja na kopijah v chernom c vete. Klinicheskoe preimushhestvo cvetnoj skennogrammy zakljuch aetsja v nep osr edstven n om opredelenii razlichij v skorosti sch et a , kotorye opredeljajut rajony razlichnoj koncentracii radioizotopov. Vypadenie cveta pri nizkoj skorosti scheta uluchshaet vozmozhnost' nabljudenija v takih rajonah, kak uchastki porazhennogo golovnogo mozga, kotorye trudno lokalizovat' vrezul't at e vysokogo fona tkanej. Cvetnaja skennogramma opredelja et kontury v sootvetstvii s tolshhinoj funkcionirujushhej tkani pecheni, kotoruju inache trudno uvidet'. Pri sravnenii normal'nyh skennogramm pecheni uchastki fibroza opuholevoj infil'tracii ra s poznajutsja gor azdolegche. Jeto spravedlivo i dlja skennogramm pochek, g d e izmenenija cveta mogut ukazat' na ishemicheskie, kistoznye ili opuholevye uchastk i . Chto ka sa et sja skennogramm shhitovidnoj zhelezy, to cvetnye otpechatki dajut vozmozhnost' provesti polukolichest-vennoe sravnenie pogloshhenija radiojoda v razlichnyh uchastkah. (author)

  10. Measurements with a Pulsed and Modulated Source in a Reactor; Mesures au Moyen d'une Source Pulsee et Modulee dans un Reacteur; Izmereniya v reaktore s pomoshch'yu impul'snogo i moduliruemogo is tochnika; Mediciones Efectuadas en Reactor con una Fuente Pulsada y Modulada

    Energy Technology Data Exchange (ETDEWEB)

    Rotter, W. [Centre d' Etude de l' Energie Nucleaire, Mol (Belgium)

    1965-10-15

    A generator with a neutron level variable in terms of any time factor has been developed by Philips Research Laboratories. Its practical use. in reactor physics has been demonstrated through a series of measurements carried out in the BRO2 reactor when subcritical. The stability of this generator, and the possibility of introducing sharp variations in the neutron intensity and of pulsing the flux or modulating it sinusoidally, makes it a very versatile instrument. It enables reactivity ({rho} = {Delta}k/{beta}) and neutron lifetime ( Script-Small-L /{beta}) to be determined by different independent methods. An exact comparison can be made of these methods since they can be employed without changing the conditions under which measurements are carried out. The following were determined: (1) {rho} based on delayed neutrons, by a sudden reduction of neutron level, (2) {rho} based on prompt neutrons by neutron pulses, (3) ( Script-Small-L /{beta}) by a combination of (1) and (2) for 0.5$ < {rho} < 2$; and (4) Script-Small-L /{beta} based on the transfer function of the reactor for a modulated source. The transfer functions for a reactivity oscillator and for a sinusoidally modulated source are discussed. It is shown that the measurement of Script-Small-L /{beta} is possible for 0.1 $ < {rho} < 10 $ by using a modulated source. The same method also gives the reactivity on the basis of the ratio of prompt neutrons to delayed neutrons for an optimal frequency, practically independently of the data for delayed neutrons and of the value of Script-Small-L /{beta}. By accumulating a large number of cycles in the multi-channel analyser, better statistics for each method can be obtained. Since the neutron level from the generator is in fact sinusoidal, the response of the reactor may be integrated over each quarter of a period, as the measurement sequence is controlled by the generator; measurement time is then minimal. Observations recorded on a perforated tape are analysed by a digital computer [French] Un generateur dont le debit neutronique est variable selon une fonction du temps quelconque a ete mis au point par les Laboratoires de recherches Philips. Son utilite pratique dans le domaine de la physique des reacteurs a ete demontree par une serie de mesures effectuees dans le reacteur BRO2 a fotat sous-critique. Sa bonne stabilite, la possibilite de faire varier brusquement l'intensite neutronique, de puiser le debit ou de le moduler sinusoldalement, rend ce generateur tres souple. Il permet de determiner la reactivite ({rho} = {Delta}k/{beta}) et le temps de vie des neutrons ( Script-Small-L /{beta}) d'apres differentes methodes independantes. Une comparaison exacte de ces methodes est possible puisqu'elles peuvent etre employees sans modifier les conditions de mesure. On a determine: a) {rho} sur la base des neutrons retardes, par une reduction instantanee du debit de neutrons; b) {rho} sur la base des neutrons instantanes par des bouffees de neutrons; c) Script-Small-L /{beta} par combinaison de a) et b) pour 0,5 $ < {rho} <2 $; d) Script-Small-L /{beta} sur la base de la fonction de transfert du reacteur pour une source modulee. Les fonctions de transfert pour un oscillateur de reactivite et pour une source modulee sinusoldalement sont discutees. Il est montre que la mesure de Script-Small-L /{beta} est possible pour 0,1 $ < {rho} < 10 $ en utilisant une source modulee. La meme methode fournit aussi la reactivite a l'aide du rapport des neutrons instantanes aux neutrons retardes pour une frequence optimale, pratiquement independamment des donnees relatives aux neutrons retardes et de la valeur de f Script-Small-L /{beta}. Par accumulation d'un grand nombre de cycles dans l'analyseur multicanal, la statistique peut etre amelioree pour chaque methode. Le debit du generateur etant bien sinusoiedal, la reponse du reacteur peut etre integree sur chaque quart d'une periode, etant donne que la chafhe de mesure est pilotee par le generateur: le temps de mesure est donc minimum. Les observations enregistrees sur bande perforee sont depouillees par une calculatrice numerique. (author) [Spanish] Los laboratorios de investigacion Philips han construido un generador neutronico de flujo variable en funcion del tiempo. Con una serie de mediciones efectuadas en el reactor BRO2 en estado subcrftico, se ha demostrado su utililidad practica en la esfera de la fisica de los reactores. El funcionamiento del generador es muy flexible debido a su alta estabilidad, a la posibilidad de variar bruscamente la intensidad neutronica, y de pulsar el flujo o modularlo de manera sinusoidal. El generador permite determinar la reactividad ({rho} = {Delta}k/{beta}) y la vida media de los neutrones ( Script-Small-L /{beta}) segun varios metodos independientes. Es posible proceder a una comparacion exacta de esos metodos, dado que pueden aplicarse sin modificar las condiciones de medicion. El autor ha calculado los siguientes valores: a) p, sobre la base de los neutrones retardados, por reduccion instantanea del flujo neutronico; b) p, sobre la base de los neutrones inmediatos, por impulsos neutronicos; c) Script-Small-L /{beta}, combinando 1) y 2), cuando 0, 5 dolares < {rho} < 2 dolares, y d) Script-Small-L /{beta}, sobre la base de la funcion de transferencia del reactor para una fuente modulada. En la memoria se examinan las funciones de transferencia correspondientes a un oscilador de reactividad y a una fuente de modulacion sinusoidal. Se demuestra que es posible medir Script-Small-L /{beta}, cuando 0,1 dolar < {rho} < 10 dolares utilizando una fuente modulada. Por el mismo metodo se obtiene tambien la reactividad partiendo de la razon neutrones inmediatos/neutrones retardados para una frecuencia optima que es practicamente independiente de los datos relativos a los neutrones retardados y del cociente Script-Small-L /{beta}. La precision estadistica de cada metodo puede aumentarse acumulando un gran numero de ciclos en el analizador multicanal. Como el flujo del generador es perfectamente sinusoidal, la respuesta del reactor puede integrarse en cada cuarto de perfodo, puesto que el circuito de medicion esta gobernado por el generador; por consiguiente, el tiempo de medicion es minimo. Los datos registrados sobre cinta perforada se analizan con ayuda de una calculadora numerica. (author) [Russian] Generator, vyhod nejtronov kotorogo izmenjaetsja v zavisimosti ot funkcii kakogo-to vremeni, byl razrabotan v issledovatel'skih laboratorijah Filipsa. Ego prakticheskaja pol'za v oblasti fiziki reaktorov byla prodemonstrirovana na serii izmerenij, provedennyh v reaktore BR-O 2 v podkriticheskom sostojanii. Horoshaja ustojchivost', vozmozhnost' proizvodit' rezkie izmenenija intensivnosti nejtronnogo potoka, impul'sirovat' vyhod ili modulirovat' ego sinusoidal'no, - vse jeto delaet takoj generator ochen' gibkim. On pozvoljaet ustanavlivat' reaktivnost' ({rho} = {Delta}k/{beta}) i vremja zhizni nejtronov ( Script-Small-L /{beta}) po razlichnym nezavisimym metodam. Tochnoe sravnenie jetih metodov vozmozhno, poskol'ku poslednie mogut byt' ispol'zovany bez izmenenija uslovij izmerenija. Ustanovleno: 1) {rho} na osnove zapazdyvajushhih nejtronov putem mgnovennogo umen'shenija vyhoda nejtronov; 2) {rho} na osnove mgnovennyh nejtronov putem ispol'zovanija impul'sov nejtronov; 3) Script-Small-L /{beta} putem soedinenija 1) i 2) dlja 0,5 $ < {rho} < 2 $ ; 4) Script-Small-L /{beta} na osnove peredatochnoj funkcii reaktora dlja moduliruemogo istochnika. Obsuzhdajutsja peredatochnye funkcii dlja oscilljatora reaktivnosti i dlja sinusoidal'no moduliruemogo istochnika. Pokazano, chto izmerenie Script-Small-L /{beta} vozmozhno dlja 0,1 $< {rho} < $ s uchetom primenenija moduliruemogo istochnika. Tot zhe metod takzhe daet reaktivnost' s pomoshh'ju otnoshenija mgnovennyh nejtronov k zapazdyvajushhim nejtronam dlja optimal'noj chastoty, prichem na praktike jeto proishodit nezavisimo ot dannyh, otnosjashhihsja k zapazdyvajushhim nejtronam, i ot znachenija Script-Small-L /{beta}. Statistika mozhet byt' uluchshena dlja kazhdogo metoda v rezul'tate nakoplenija bol'shogo kolichestva ciklov v mnogokanal'nom analizatore. Esli vyhod s generatora dostatochno sinusoidalen, to chuvstvitel'nost' reaktora mozhet byt' integrirovana dlja kazhdoj chetverti perioda pri uslovii, chto cep' izmerenij upravljaetsja generatorom; pojetomu vremja izmerenija minimal'no. Zaregistrirovannye na perforirovannoj lente nabljudenija rasshifrovyvajutsja na cifrovom vychislitel'nom ustrojstve. (author)

  11. Study of inclusions and segregation in metals by autoradiography; Etude autoradiographic des inclusions et de la segregation dans les metaux; Izuchenie primesej i usadki metalla s pomoshch'yu avtoradiografii; Estudio autoradiografico de las inclusiones y de la segregacion en los metales

    Energy Technology Data Exchange (ETDEWEB)

    Makin, S M [Wantage Research Laboratory, Wantage, Berks (United Kingdom)

    1962-01-15

    Three applications of radioisotope techniques to metallurgy are described. During the course of this work, new autoradiographic techniques are developed. These include the irradiation and autoradiography of extraction replicas, similar to those used in electron microscopy, and a two-colour dye-transfer process in which colour prints of autoradiographs are shown with the corresponding micrographs superposed. These methods are applied to the study of inclusions in steel and uranium and to an investigation of the segregation of sulphur and phosphorus in welds in stainless steel. (author) [French] Le memoire decrit trois applications des radioisotopes en metallurgie. Au cours de ces travaux, l'auteur a mis au point de nouvelles techniques d'autoradiographie. Celles-ci comportent l'irradiation d'empreintes pour autoradiographie et d'empreintes d'extraction, semblables a celles qui sont employees dans la microscopie electronique, et font appel a un procede de transfert en deux couleurs dans lequel on superpose des autoradiographies en couleur et les microphotographies correspondantes. Ces methodes sont appliquees a l'etude des inclusions dans l'acier et l'uranium ainsi qu'aux recherches sur la segregation du soufre et du phosphore dans les pieces soudees en acier inoxydable. (author) [Spanish] Se describen tres aplicaciones de las tecnicas de los radioisotopes en la metalurgia. En el curso de los experimentos se han perfeccionado nuevas tecnicas autorradiograficas, que comprenden la irradiacion de replicas de autorradiografia y extraccion, analogas a las utilizadas en la microscopia electronica y un procedimiento de impresion a dos colores que permite obtener autorradiografias superpuestas a las correspondientes micrografias. Estos metodos se aplican al estudio de inclusiones en el acero y el uranio y a una investigacion de la segregacion del azufre y del fosforo en soldaduras hechas en acero inoxidable. (author) [Russian] Daetsya opisanie trekh sposobov primeneniya radioizotopov v metallurgii. V khode ehtoj raboty byli sozdany novye avtoradiograficheskie metody. Oni vklyuchayut obluchenie i avtoradiografiyu ehkstraktsionnykh modelej, podobno ispol'zuemym v ehlektronnoj mikroskopii, i protsess dvukhtsvetnogo perekhoda, pri kotorom tsvetnye kopii chertezhej avtoradiografa pokazyvayutsya s sootvetstvuyushchimi nalozhennymi dannymi mikrografov. EHti metody ispol'zuyutsya pri izuchenii primesej v stali i urane i pri issledovanii segregatsii sery i fosfora pri svarke v nerzhaveyushchej stali. (author)

  12. Taiwan zhanhou chuqi wenxue changyu chongjian : Shuwei renwen gangfa de yunyong yu shilie fenxi 台灣戰後初期文學場域重建:數位人文方法的運用與實例分析

    Czech Academy of Sciences Publication Activity Database

    Dluhošová, Táňa; Chen, A.Ch.-H.

    -, č. 27 (2015), s. 113-152 ISSN 1608-1692 Grant - others:AV ČR(CZ) MOST/2014/0004 Program:Bilaterální spolupráce Institutional support: RVO:68378009 Keywords : Early Post-war Literature * Digital Humanities * Literary Field * Multivariate analysis * Literary Autonomy Subject RIV: AJ - Letters, Mass-media, Audiovision

  13. FY 1998 annual report on the research on the possibility of introducing a usable chemical substance manufacturing system by utilizing natural gas containing CO2; CO{sub 2} gan'yu tennen gas den katsuyo ni yoru yuyo kagaku busshitsu seizo system donyu kanosei ni kansuru chosa kenkyu 1998 nendo chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The trends of effective use of gas containing CO2 from natural gas fields are surveyed, and usable chemical substance manufacturing systems which utilize natural energy are investigated, evaluated and analyzed, to extract promising systems for effective use of CO2-containing natural gas and thereby to promote its effective use. Chapter 1 outlines possibility of integrated use of gas containing CO2 from natural gas fields and natural gas energy. Chapter 2 describes the research trends in the CO2 conversion reactions for using unexploited CO2 as the carbon source. Chapter 3 describes natural energy utilization technology applicable to gas containing CO2 from natural gas fields. Chapter 4 describes performance of chemical manufacturing systems utilizing natural gas containing CO2. The energy balances and CO2 emission coefficients are estimated, based on the above. The evaluation is implemented in the order of (1) conventional steam reforming, (2) steam reforming in which heat is supplied by a solar furnace, (3) examination of the exhaust gases from a methanol synthesis process, and (4) examination of CO2-mixed reforming. Chapter 5 describes summary and proposals. (NEDO)

  14. Control Rods in high-Flux Swimming-Pool Reactors; Les Barres de Controle dans les Piles Piscines a Haut Flux; Reguliruyushchie sterzhni dlya reaktorov bassejnovogo tipa s vysokoj plotnost'yu nejtronnogo potoka; Las Barras de Control en los Reactores Tipo Piscina de Flujo Elevado

    Energy Technology Data Exchange (ETDEWEB)

    Ageroni, P.; Blum, P.; Denielou, G.; Denis, P.; Meunier, C. [Centre d' Etudes Nucleaires de Grenoble (France)

    1964-06-15

    Control-rod problems in open swimming-pool high-flux and high specific power research reactors are examined in the light of the calibrations and experiments made during the construction of the SILOE reactor. Control-rod operating experience for this reactor at 13 MW is also described. 2. The following are considered in turn: (a) Reactivity balances and reactivity values for the different types of rod tested (cadmium, B4C , rare earths and combinations of these different elements). (b) Flux peaks set up in the core by the presence of the control rods, their incidence on the specific power, the fast fluxes that can be obtained and means of increasing them. (c ) The technological problems involved in constructing the rods. (d) In-pile cooling, vibration, deformation and scram-time problems. 3. In conclusion, current studies on control rods in open swimming-pool reactors operating in the 10 - 30 1W range are briefly summarized. (author) [French] 1. Les problemes poses par les barres de controle dans les reacteurs de recherche de type piscine ouverte a haute puissance specifique et haut flux sont examines a la lumiere des calculs et des experiences effectues pendant la construction du reacteur SILOE. Les resultats de l'experience de fonctionnement a 13 MW de ce reacteur sont egalement presentes en ce qui concerne les barres de controle. 2. On examine successivement: a) les bilans de reactivite et les valeurs en reactivite des differents types de barres qui ont ete essayes (Cadmium, B 4C , terres rares et combinaisons de ces differents elements). b) Les pics de flux crees dans le coeur par la presence de barres de controle, leur incidence sur la puissance specifique, et les flux rapides que l'on peut obtenir ainsi que les moyens correspondants d'accroitre ces flux. c) Les problemes technologiques poses par la construction des barres. d) Les problemes de refrigeration, de vibration, de deformation, de temps de chute en pile. 3. En conclusion on decrit sommairement les etudes en cours sur les barres de controle des piles piscine a coeur ouvert fonctionnant dans la bande de 10 a 30 MW. (author) [Spanish] La memoria examina los problemas planteados por las barras de control en los reactores de investigacion de tipo piscina abierta, de alta potencia especifica y elevado flujo, basandose en calculos y experimentos efectuados durante la construccion del reactor SILOE. Expone asimismo la experiencia adquirida con las barras de control mientras el reactor funcionaba a 13 MW. Examina sucesivamente: a) Los balances de reactividad y los valores de esta para los diversos tipos de barras de control que se han ensayado (cadmio, B4C, tierras raras, y combinaciones de estas sustancias); b) los picos de flujo que la presencia de barras de control crea en el cuerpo del reactor, su influencia sobre la potencia especifica, los flujos rapidos que se pueden obtener y los medios para incrementarlos; c) los problemas tecnologicos planteados por la construccion de las barras; d) los problemas de refrigeracion, vibracion, deformacion y tiempo necesario para introducirlos en el reactor. Para terminar, describe someramente loe estudios que se estan realizando con las barras de control de reactores de tipo piscina de cuerpo abierto cuando funcionan en el intervalo de potencias comprendido entre 10 y 30 MW. (author) [Russian] 1. V svete raschetov i jeksperimentov, provedennyh pri postrojke reaktora STLOE , rassmatrivajutsja problemy, voznikajushhie v svjazi s regulirujushhimi sterzhnjami dlja issledovatel'skih reaktorov otkrytogo bassejnovogo tipa s bol'shoj udel'noj moshhnost'ju i s vysokoj plotnost'ju nejtronnogo potoka. Privodjatsja takzhe rezul'taty ispytanija jetogo reaktora pri .moshhnosti 13 mgvt v svjazi s razlichnymi regulirujushhimi sterzhnjami. 2. Posledov atel'no rassmatrivajutsja sledujushhie problemy: a) balans reaktivnosti i reaktivnaja sposobnost' podvergnutyh ispytanijam regulirujushhih sterzhnej razlichnyh tipov (kadmij, B{sub 4}C , redkie zemli i kombinacii jetih razlichnyh jelementov); b) piki potokov, sozdavaemyh v aktivnoj zone prisutstviem regulirujushhih sterzhnej, iz vlijanie na udel'nuju moshhnost', potoki bystryh nejtronov, kotorye mogut byt' polucheny takim obrazom, a takzhe sposoby usilenija jetih potokov; v) tehnologicheskie problemy, voznikajushhie v svjazi s izgotovleniem regulirujushhih sterzhnej; g) problemy ohlazhdenija, vibracii, deformacii i vremeni bystrogo zakrytija na dejstvujushhem reaktore. 3. V zakljuchenie daetsja kratkij obzor provodimogo v nastojashhee vremja izuchenija regulirujushhih sterzhnej dlja reaktorov bassejnovogo tipa s otkrytoj aktivnoj zonoj, rabotajushhih v diapazone moshhnostej 10 - 30 mgvt. (author)

  15. Identification and estimation ot carbohydrates using radioisotopic methods; Identification et dosage des hydrates de carbone a l'aide des radioisotopes; Identifikatsiya i opredelenie karbogidratov s pomoshch'yu radioizotopnykh metodov; Identificacion u valoracion de hidratos de carbono con ayuda de radioisotopos

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, G O; Criddle, W J [Department of Chemistry, University College, Cardiff (United Kingdom)

    1962-01-15

    Isotope-dilution methods have been developed to identify and estimate the small amount of products formed when carbohydrates are irradiated in aqueous solution with Co{sup 60} gamma-radiation. Conventional analytical methods proved inadequate. After irradiation of C{sup 14}-sugar solutions, the autoradiographs prepared after paper chromatography indicated extensive degradation. Using a reverse isotope-dilution procedure involving the addition of known carriers, and conversion of the fragments into crystalline derivatives, various constituents were quantitatively determined. It is possible to distinguish between d- and Z-isomers, and estimate each isomer independently. The method is applicable to other analytical problems in carbohydrate chemistry. A new method for scanning and recording the radioactivity along paper-chromatogram strips, which involves an inexpensive modification to conventional counting equipment, is described. (author) [French] On a mis au point des methodes de dilution isotopique destinees a identifier et a doser les menues quantites de produits qui se forment lorsque des hydrates de carbone en solution aqueuse sont irradies par les rayons gamma du cobalt-60. A cet egard, les methodes d'analyse classiques se sont revelees inadequates. Apres irradiation de solutions de sucre marque au carbone-14, les autoradiogrammes etablis a la suite d'une chromatographic sur papier indiquaient une forte degradation. En recourant a une methode de dilution isotopique inverse, avec adjonction d'entraineurs connus, et en operant une conversion des fragments en derives cristallins, on a pu determiner quantitativement plusieurs elements constitutifs. Il est possible de distinguer les isomeres dextrogyres des isomeres levogyres et de doser chaque isomere independamment. La methode peut etre appliquee a d'autres problemes d'analyse dans la chimie des hydrates de carbone. Le memoire decrit une nouvelle methode permettant d'explorer et d'enregistrer la radioactivite de chromatogrammes sur bandes de papier; elle n'exige qu'une modification peu couteuse du materiel de comptage traditionnel. (author) [Spanish] Dado que los metodos analiticos clasicos no permiten obtener resultados satisfactorios, los autores han perfeccionado unos metodos de dilucion isotopica para identificar y valorar los productos que se forman en pequenas cantidades al exponer hidratos de carbono en solucion acuosa a las radiaciones gamma del {sup 60}Co. Las autorradiografias de cromatogramas sobre papel, obtenidos despues de irradiar soluciones de azucares marcados con {sup 14}C, revelan una considerable degradacion molecular. Gracias a un metodo de dilucion isotopica inverso basado en la adicion de portadores conocidos, y en la obtencion de derivados cristalizados de los fragmentos, los autores han podido determinar cuantitativamente los siguientes constituyentes. El metodo descrito por los autores permite distinguir entre estereoisomeros y valorar cada lino de ellos por separado. Asimismo puede utilizarse para resolver otros problemas de orden analitico que plantea la quimica de los hidratos de carbono. Los autores describen un nuevo metodo de exploracion y registro de la radiactividad a lo largo de las tiras de papel en las que se ha desarrollado el cromatograma. Este metodo solo requiere una modificacion poco onerosa del equipo de recuento corriente. (author) [Russian] Dlya identifikatsii i otsenki nebol'shikh kolichestv obrazovavshikhsya produktov pri obluchenii karbogidratov v vodnom rastvore gamma-aktivnym kobal'tom-60 byli razrabotany metody razbavleniya izotopov. Obychnye zhe analiticheskie metody okazalis' nedostatochnymi. Po obluchenii rastvorov S14-sakhar podgotovlennye avtoradiografii posle khromatografii na bumage ukazyvayut na znachitel'noe snizhenie. Ispol'zovanie protsedury obratnogo izotopnogo rastvora, svyazannoj s dobavkoj izvestnykh nositelej i preobrazovaniem oskolkov v derivaty kristallov, byli opredeleny kolichestvennye razmery sleduyushchikh sostavnykh chastej : Mozhno razlichit' d- i i-izomery i proizvesti individual'nuyu otsenku kazhdogo iz nikh. EHtot metod primenyaetsya pri reshenii drugikh analiticheskikh problem v khimii karbogidratov. V doklade daetsya opisanie novogo metoda graficheskogo izobrazheniya i zapisi radio- aktivnosti po liniyam khromogrammy na bumage, chto vozmozhno osushchestvit' pri neznachitel'nykh zatratakh na modifikatsiyu obychnogo schetnogo oborudovaniya. (author)

  16. FY 1999 report on the results of a feasibility study on a system for producing useful chemical substances by utilizing CO2-containing natural gas fields. II; 1999 nendo CO{sub 2} gan'yu tennen gas den katsuyo ni yoru yuyo kagaku busshitsu seizo system donyu kanosei ni kansuru chosa kenkyu. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The paper studied the solar energy use methanol synthesis using CO2 as raw material in the natural gas field with which a large quantity of CO2 is associated. This is a report on the FY 1999 survey. It was found that comparatively many natural gas fields containing CO2 exist also in Asia/Oceania regions. It was also found that when considering the climate and the transportation to Japan, Australia has more advantages in terms of the effective desert area, etc. and is the best site for solar system construction. Various solar concentrating/collecting methods now under development are roughly viewed to extract characteristics and developmental conditions. As to the reforming reaction furnace, it is necessary not only to absorb the world technology, but to develop Japan's original one. The conceptual design and assessment of the system were conducted. About the associated CO2, a limit of the concentration for use was estimated at 25%. In the study of elements of system structure, examined was the thermally combined simulation of heat flow and chemical reaction in the solar heat reaction furnace, and simple models were calculated and subjects were extracted. In a comparison with the conventional methanol synthesis method, this system was found to be excellent in conservation of fossil fuel resources and reduction in CO2 emissions. (NEDO)

  17. Propuesta de metodología para la estimación de la resistencia del hormigón en un punto de una estructura a través de ensayos de información, en éste y/u otros puntos

    Directory of Open Access Journals (Sweden)

    Buxade Ribot, Carlos

    1976-02-01

    Full Text Available The destructive character of the extraction of test specimens, which at present is the only test that provides trustworthy data with regard to strength, makes it necessary to assign a strength to areas in the structure that are at a greater or lesser distance from the extraction points. The variables of the problem are the number of extractions and their emplacement. At one end we would have the case in which samples are taken from all the structural parts at the risk of weakening the structure, above all during the sampling process itself, as well as the negative financial and time factors, that this procedure would imply. At the other far end we would place the case of evaluating the strength in a great structural area on the basis of the results from breaking a small quantity of test pieces, by way of an extrapolation without the required guarantees. Naturally, the number of test and their emplacement situates the problem in between the two above mentioned extremes. The necessary extrapolation of some results that by nature are not exhaustive, is then carried out with greater or lesser guarantee with regard to advance knowledge of the execution of the work: the greater this knowledge is, the easier it is to establish the strength relation between the specimens and the pieces, which without being represented directly by samples, can adapt themselves to their characteristics, either by proximity or known execution rhythm. The most important problem arises when there is not enough knowledge on how the work was carried out, so that it is impossible to relate the strength of the test specimens with the actual strength of the rest of the structure under investigation. In this case it does not seem possible to establish the relation between two points in the structure other than on the basis of the actual physical distances and the results obtained through the test specimens. This report dealts with the application of the Information theory to quantify these relations and to group the points at which the concrete strength is estimated.El carácter destructivo de la extracción de probetas testigo, actualmente el único ensayo de información que facilita datos de partida fidedignos desde el punto de vista resistente, obliga a asignar una resistencia a zonas de la estructura más o menos lejanas de los puntos de extracción. Las variables del problema son el número de extracciones y su localización. En un extremo tendríamos el caso de la obtención de testigos en todas las piezas estructurales, con el consiguiente riesgo de debilitación de la estructura, sobre todo durante las operaciones necesarias para ello, y el gravoso factor económico y de tiempo que este planteamiento lleva aparejado. En el otro extremo se situaría el caso de la evaluación de la resistencia de una gran zona de estructura en base a los resultados de la rotura de un mínimo número de probetas, a través de una extrapolación sin las necesarias garantías. Naturalmente, el número de ensayos de Información y su localización sitúa el problema en una región intermedia entre los dos extremos expuestos. La necesaria extrapolación de unos resultados, forzosamente no exhaustivos, se realiza, entonces, con una mayor o menor garantía en función del conocimiento previo de la ejecución de la obra: cuanto mayor es este conocimiento más fácilmente se podrá establecer la relación de resistencias entre los testigos y las piezas que, sin tener probetas que los representen directamente, puedan, por proximidad o ritmo de ejecución conocido, asimilarse a las características de dichos testigos. El problema más grave se plantea cuando el desconocimiento de la ejecución de la obra no permite establecer nexos de conocimiento entre los resultados obtenidos en determinados testigos y el resto de la zona de estructura cuya capacidad resistente se trata de evaluar. En este caso no parece posible el establecimiento de relaciones entre dos puntos de la estructura más que basándose en las distancias físicas y los resultados obtenidos en los testigos ensayados. Este trabajo trata de la aplicación de la teoría de la información para cuantificar estas relaciones y agrupar los puntos en los cuales el hormigón es objeto de estimación resistente.

  18. Scintillation Scanning of the Spleen with Red Cells Labelled with Cr{sup 51}; Scintigraphie de la Rate au Moyen d'Hematies Marquees au Chrome-51; Stsintillyatsionnoe skennirovanie selezenki s pomoshch'yu ehritrotsitov mechennykh Khromom-51; Exploracion Centelleografica del Bazo Mediante Eritrocitos Marcados con Cromo-51

    Energy Technology Data Exchange (ETDEWEB)

    Spinelli-Ressi, F. [Istituto di Radiologia e Medicina Nucleare, Ospedale Maggiore, Milan (Italy)

    1964-10-15

    Satisfactory scintiscans of the spleen have been obtained using chromium-51-labelled red cells, modified by two methods. Initially red cells were sensitized in vitro by coating with incomplete anti-D antibody. In this method the concentration of sensitized red cells in the spleen is proportional to the volume of anti- D serum employed in the sensitization procedure. Satisfactory scintiscans were obtained using 0.50 ml of a 1:128 dilution of anti-D serum, having an original titre of 1: 512/ml of red cells. In spite of good results, the sensitization method, utilizable only in Rh positive patients, has been replaced by the method using red cells modified by heating, which is technically easier and may be used also in Rh negative patients. The image of the spleen is clearly delineated in all the cases, without interference from hepatic radioactivity. The spleen: liver ratio ranges between 5:1 and 10:1. To date scintillation scans of the spleen have been performed in about 60 patients. No immediate or delayed clinical reactions have been observed in the patients after the injection of sensitized or heated red cells. Since the radiation dose delivered to the patient is lower than the dose delivered in many radiological and clinical examinations with radioactive isotopes, the scanning procedure has been widely used in the differential diagnosis of the masses of the left abdomen. Among the cases studied, it is worth while mentioning two cases of splenomegaly associated with a tumour of the left kidney, one case of Banti's disease in a patient, in which a neoplasm of descending colon was suspected and a case of neuroblastoma in a patient two years old, in which the scintiscan of the spleen and that of the kidneys were of great help in making the right diagnosis. Further, the scintiscan has been of unique utility to rule out an accessory spleen and to demonstrate the spleen in congenital malformations, like situs inversus viscerum. In patients affected by chronic leukaemia the scanning procedure has been used in objectively demonstrating modifications in spleen size after roentgen- ray therapy. (author) [French] L'auteur a obtenu des scintigrammes satisfaisants de la rate au moyen d'hematies marquees au chrome-51, alterees suivant deux methodes differentes. La methode utilisee en premier lieu consistait a sensibiliser les hematies in vitro en les revetant d'anticorps anti-D incomplet. Avec cette methode, la concentration dans la rate des hematies sensibilisees est proportionnelle au volume de serum anti-D utilise pour la sensibilisation. L'auteur a obtenu des scintigrammes satisfaisants en utilisant, par ml d'hematies, 0,50 ml de serum anti-D dilue a 1:128, dont le titre initial etait de 1:512. Bien qu*elle ait donne de bons resultats, la methode de sensibilisation, qui ne peut etre utilisee que chez des patients a Rh positif, a ete remplacee par une autre methode dans laquelle les hematies sont alterees thermiquement; cette seconde methode est techniquement plus facile et peut egalement etre appliquee chez des patients a Rh negatif. L'image de la rate est nettement delimitee dans tous les cas, sans interference due a la radioactivite hepatique. Le rapport rate:foie varie entre 5 et 10. A ce jour, l'auteur a etabli des scintigrammes de la rate pour une soixantaine de patients. Aucune reaction clinique, immediate ou differee, n*a ete observee a la suite de l'injection d'hematies sensibilisees ou alterees thermiquement. La dose de rayonnement delivree au patient etant inferieure a la dose administree dans de nombreux examens radiologiques et cliniques au moyen des radioisotopes, cette methode scintigraphique est largement utilisee a l'hopital de l'auteur pour le diagnostic differentiel des masses de la partie gauche de l'abdomen. Parmi les cas etudies, il convient de citer deux cas de splenomegalie associee a une tumeur du rein gauche, un cas de maladie de Banti chez un sujet presentant les symptomes d'un neoplasme du colon descendant et un cas de neuroblastome chez un enfant de deux ans, que la scintigraphie de la rate et des reins a beaucoup aide a diagnostiquer correctement. En outre, la scintigraphie peut seule permettre d'ecarter l'hypothese d'une rate accessoire et de visualiser la rate dans les malformations congenitales telles que l'inversion viscerale. Chez les sujets atteints de leucemie chronique, la scintigraphie a permis d'obtenir une preuve objective des modifications de la taille de la rate apres roentgentherapie. (author) [Spanish] El autor ha obtenido centelleogramas satisfactorios del bazo empleando eritrocitos marcados con cromo-51, modificados por dos procedimientos. Al principio, sensibilizaba los eritrocitos in vitro recubriendolos con un anticuerpo incompleto anti-D. Con este procedimiento la concentracion en el bazo de eritrocitos sensibilizados resulta proporcional al volumen del suero anti-D empleado para su sensibilizacion. Con 0,50 mi de una solucion de suero anti-D, diluida al 1:128 a partir de un titulo inicial de 1: 512, por milimetro de eritrocitos, se han conseguido centelleogramas satisfactorios. Pese a sus buenos resultados, este procedimiento de sensibilizacion, que solo puede aplicarse a pacientes con Rh po: itivo, fue sustituido por un metodo basado en el empleo de eritrocitos modificados por la accion del calor, metodo que es mas facil de utilizar y que puede aplicarse tambien a pacientes con Rh negativo. En todos los casos la imagen del bazo aparece claramente delineada, sin ninguna interferencia de la radiactividad hepatica. La razon bazo/higado varia entre 5:1 y 10:1. Hasta ahora el autor ha procedido a la exploracion centelleografica del bazo de unos 60 pacientes. No ha observe do en estos ultimos ninguna reaccion clinica inmediata ni retardada despues de la inyeccion de los eritrocitos sensibilizados o calentados. Como la dosis de radiacion recibida por el paciente es inferior a la que se administra en muchos examenes radiologicos y clinicos efectuados mediante isotopos radiactivos, este procedimiento de exploracion ha sido muy utilizado para el diagnostico diferencial de las masas de la mitad izquierda del abdomen. Entre los casos estudiados, cabe mencionar dos de esplenomegalia acompanada de tumor del rinon izquierdo, uno de enfermedad de Banti en el que se sospechaba la presencia de un neoplasma del colon descendente, y otro de neuroblastoma en un nino de dos anos, cuyo diagnostico fue facilitado por el centelleograma del bazo y de los rinones. La exploracion centelleografica ha sido, ademas, de suma utilidad para descartar la existencia de un bazo suplementario y senalar malformaciones congenitas del bazo, tales como un situs inversus viscerum. En pacientes afectados por leucemia cronica este procedimiento de exploracion ha servido para demostrar objetivamente la existencia de modificaciones del tamano del bazo causadas por una aplicacion terapeutica de rayos X. (author) [Russian] Udovletvoritel'nye scintigrammy selezenki byli polucheny pri ispol'zovanii jeritrocitov, mechennyh hromom-51, chto osushhestvljalos' dvumja sposobami. Pervonachal'no jeritrocity sensibilizirovali in vitro putem vozdejstvija nepolnogo anti-D antitela. Pri takom metode koncentracija sensibilizirovannyh jeritrocitov v selezenke proporcional'na ob{sup e}mu primenjaemoj v processe sensibilizacii syvorotki anti-D . Udovletvoritel'nye scintigrammy byli polucheny pri ispol'zovanii 0,50 ml syvorotki anti-D v razbavlenii 1: 128, pri pervonachal'nom titre 1:512, na 1 ml jeritrocitov. Nesmotrja na horoshie rezul'taty, metod sensibilizacii, primenimyj lish' u rezus-polozhitel'nyh bol'nyh, byl zamenen metodom s ispol'zovaniem jeritrocitov, vidoizmenennyh posredstvom nagrevanija, kotoryj v tehnicheskom otnoshenii gorazdo proshhe i mozhet ispol'zovat'sja i u re- zus-otricatel'nyh bol'nyh. Izobrazhenie selezejki imelo chetkuju konfiguraciju vo vseh sluchajah bez kakih libo pomeh za schet radioaktivnosti pecheni. Sootnoshenie selezenka-pechen' kolebletsja v predelah mezhdu 5: 1 i 10: 1 . K nastojashhemu momentu scintigrammy pecheni polucheny pochti u 60 bol'nyh. U bol'nyh posle in{sup e}kcii sensibilizirovannyh ili podogretyh jeritrocitov ne nabljudalos' neposredstvennyh ili otdalennyh klinicheskih reakcij. Poskol'ku doza radiacii, poluchennaja bol'nym, men'she dozy, poluchaemoj pri mnogih radiologicheskih i klinicheskih issledovanijah za schet radioaktivnyh izotopov, to procedura skennirovanija shiroko ispol'zovalas' dlja differencial'noj diagnostiki obrazovanij v levoj polovine brjushnoj polosti. Sredi izuchavshihsja sluchaev zasluzhivajut upominanija dva sluchaja splenomegalii, sochetavshiesja s opuhol'ju levoj pochki, odin sluchaj bolezni Banti u bol'nogo, gde predpolagalos' nalichie novoobrazovanija v nishodjashhej petle tolstoj kishki, a takzhe sluchaj nenroblastomy u dvuhletnego rebenka, pri kotoroj scintigramma selezenki i pochek okazyvajut bol'shuju pomoshh' dlja postanovki pravil'nogo diagnoza. Krome togo, scintigramma javilas' unikal'nym metodom dlja iskljuchenija dobavochnoj selezenki i dlja demonstracii selezenki pri vrozhdennyh anomalijah, podobnyh obratnomu raspolozheniju vnutrennostej. U bol'nyh hronicheskoj lejkemiej skennirovanie ispol'zovalos' dlja ob{sup e}ktivnoj demonstracii izmenenija razmerov selezenki posle rentgenoterapii. (author)

  19. Analysis of Popper's Experiment and Its Realization

    Science.gov (United States)

    Qureshi, T.

    2012-04-01

    An experiment proposed by Karl Popper to test the standard interpretation of quantum mechanics was realized by Kim and Shih. We use a quantum mechanical calculation to analyze Popper's proposal, and find a surprising result for the location of the virtual slit. We also analyze Kim and Shih's experiment, and demonstrate that although it ingeniously overcomes the problem of temporal spreading of the wave-packet, it is inconclusive about Popper's test. We point out that another experiment which (unknowingly) implements Popper's test in a conclusive way, has actually been carried out. Its results are in contradiction with Popper's prediction, and agree with our analysis.

  20. Predictive factors warrant screening for obstructive sleep apnea in COPD: a Taiwan National Survey

    Directory of Open Access Journals (Sweden)

    Hang LW

    2016-03-01

    Full Text Available Liang-Wen Hang,1,2 Jeng-Yuan Hsu,3 Chee-Jen Chang,4 Hao-Chien Wang,5,6 Shih-Lung Cheng,7,8 Ching-Hsiung Lin,9 Ming-Cheng Chan,3 Chin-Chou Wang,10 Diahn-Warng Perng,11 Chong-Jen Yu5,6 On behalf of the Taiwan COPD Consortium 1Department of Respiratory Therapy, College of Health Care, China Medical University, 2Sleep Medicine Center, Department of Pulmonary and Critical Care Medicine, China Medical University Hospital, 3Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, 4Biostatistical Center for Clinical Research, Chang Gung Memorial Hospital, Linkou Branch, Guishan Township, Taoyuan County, 5Department of Internal Medicine, National Taiwan University Hospital, 6Department of Internal Medicine, National Taiwan University, College of Medicine, Taipei, 7Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, 8Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li City, Taoyuan County, 9Division of Chest Medicine, Changhua Christian Hospital, Changhua City, Changhua County, 10Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 11Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China Background and objectives: COPD and obstructive sleep apnea (OSA share similar pathological processes and cardiovascular sequelae. Coexisting OSA in COPD – “overlap syndrome” – has worse prognosis than either condition alone, and appropriate treatment improves survival. Our objectives were to ascertain the frequency at which COPD coexists with the risk of OSA in Taiwan and to compare the risk factors, COPD symptoms, and life quality metrics between COPD subgroups with versus without risk of OSA. Methods: We conducted a random cross-sectional national telephone survey of adults >40 years old in Taiwan. Participants fulfilling an epidemiological case definition of COPD completed a

  1. Real-world evaluation of compliance and preference in Alzheimer’s disease treatment: an observational study in Taiwan 

    Directory of Open Access Journals (Sweden)

    Lai TH

    2016-03-01

    Full Text Available Tzu-Hsien Lai,1,2,* Wen-Fu Wang,3,* Bak-Sau Yip,4 Yu-Wan Yang,5 Giia-Sheun Peng,6 Shih-Jei Tsai,7,8 Yi-Chu Liao,9 Ming-Chyi Pai10,111Section of Neurology, Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei, 2Department of Neurology, National Yang-Ming University School of Medicine, Taipei, 3Department of Neurology, Changhua Christian Hospital, Changhua, 4Department of Neurology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, 5Department of Neurology, China Medical University Hospital, Taichung, 6Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, 7Department of Neurology, Chung Shan Medical University Hospital, Taichung, 8School of Medicine, Chung Shan Medical University, Taichung, 9Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 10Division of Behavioral Neurology, Department of Neurology, 11Alzheimer’s Disease Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan City, Taiwan *These authors contributed equally to this workPurpose: Among the medications approved for Alzheimer’s disease (AD, rivastigmine is the only one available as transdermal patch. The aim of this study was to evaluate compliance and caregivers’ preference with oral and transdermal (rivastigmine monotherapy in patients with mild-to-moderate AD from Taiwan.Methods: Real-world Evaluation of Compliance And Preference in Alzheimer’s disease treatment (RECAP in Taiwan was a prospective, noninterventional, observational study with a 24-week (±8 weeks observational period for each participant. Eligible patients were grouped into one of the two treatment cohorts based on the baseline AD therapy: oral (donepezil, galantamine, rivastigmine, or memantine or transdermal (rivastigmine patch. The primary end points were caregiver preference and caregiver assessment of patients’ compliance to

  2. The prevalence and correlates of the positive Androgen Deficiency in the Aging Male (ADAM questionnaire among psychiatric outpatients: a cross-sectional survey of 176 men in a general hospital in Taiwan

    Directory of Open Access Journals (Sweden)

    Lee CP

    2015-01-01

    Full Text Available Chin-Pang Lee,1,2 Yu Chen,2–4 Kun-Hao Jiang,2,4,5 Chun-Lin Chu,1,2,4 Shih-Chieh Hsu,1,2,4 Jiun-Liang Chen,2,4,5 Ching-Yen Chen1,2,41Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan; 2Men’s Health Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 3Department of Urology, Chang Gung Memorial Hospital, Linkou, Taiwan; 4School of Medicine, Chang Gung University, Taoyuan; 5Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Linkou, TaiwanIntroduction: The Androgen Deficiency in the Aging Male (ADAM questionnaire is widely used to screen for late-onset hypogonadism. The positive response to the ADAM questionnaire (positive ADAM has been associated with depression and poorer quality of life in a number of studies. It is unclear whether there is any value of the ADAM questionnaire in psychiatric populations. In this study, we aimed to determine the utility of the ADAM questionnaire in a convenient sample of male psychiatric outpatients.Methods: One hundred and seventy-six men (mean age: 54.3 years; standard deviation: 10.7 years; range: 40–80 years completed the ADAM questionnaire, the Hospital Anxiety and Depression Scale (HADS, and the Aging Males’ Symptoms (AMS scale. Anxiety was defined as a HADS anxiety subscore ≥8; depression as a HADS depression subscore ≥8; and moderate/severe impairment of health-related quality of life (HQoL as AMS ≥37. ADAM, anxiety, and depression was used to model the moderate/severe impairment of HQoL.Results: One hundred and sixty-four (93% men had positive ADAM. Positive ADAM was associated with a lower body mass index (P<0.05 and moderate/severe impairment of HQoL (P<0.001, but was not associated with anxiety or depression (P>0.05. Positive ADAM was associated with five symptoms of the AMS scale: “decline of one’s feeling of general well-being”, “depressive mood”, and three sexual symptoms. In regression analysis, positive ADAM was associated with

  3. COPD in Taiwan: a National Epidemiology Survey

    Directory of Open Access Journals (Sweden)

    Cheng SL

    2015-11-01

    Full Text Available Shih-Lung Cheng,1,2 Ming-Cheng Chan,3 Chin-Chou Wang,4 Ching-Hsiung Lin,5 Hao-Chien Wang,6 Jeng-Yuan Hsu,3 Liang-Wen Hang,7,8 Chee-Jen Chang,9 Diahn-Warng Perng,10,* Chong-Jen Yu6,* On behalf of the Taiwan COPD Consortium 1Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, 2Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li City, Taoyuan County, 3Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, 4Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 5Division of Chest Medicine, Changhua Christian Hospital, Changhua City, Changhua County, 6Department of Internal Medicine, National Taiwan University Hospital, Taipei, 7Department of Pulmonary and Critical Care Medicine, Sleep Medicine Center, China Medical University Hospital, 8Department of Respiratory Therapy, College of Health Care, China Medical University, Taichung, 9Biostatistical Center for Clinical Research, Chang Gung Memorial Hospital, Linkou Branch, Guishan Township, Taoyuan County, 10Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China *These authors contributed equally to this work Objectives: To determine the prevalence of COPD in Taiwan and to document the disease characteristics and associated risk factors.Methods: We conducted a random cross-sectional national survey of adults older than 40 years in Taiwan. Respiratory health screening questions identified subjects with diagnosed COPD or whose reported symptoms also fulfilled an epidemiological case definition; these were eligible to complete the survey, which also included indices of symptom severity and disability and questions on comorbidities, medical treatments, smoking habits, and occupations potentially harmful to respiratory health. Subjects with diagnosed COPD were subdivided by smoking status. Subjects who fulfilled the case definition

  4. Impact of harmful use of alcohol on the sedation of critical patients on mechanical ventilation: A multicentre prospective, observational study in 8 Spanish intensive care units.

    Science.gov (United States)

    Sandiumenge, A; Torrado, H; Muñoz, T; Alonso, M Á; Jiménez, M J; Alonso, J; Pardo, C; Chamorro, C

    2016-05-01

    To evaluate the impact of a history of harmful use of alcohol (HUA) on sedoanalgesia practices and outcomes in patients on mechanical ventilation (MV). A prospective, observational multicentre study was made of all adults consecutively admitted during 30 days to 8 Spanish ICUs. Patients on MV >24h were followed-up on until discharge from the ICU or death. Data on HUA, smoking, the use of illegal (IP) and medically prescribed psychotropics (MPP), sedoanalgesia practices and their related complications (sedative failure [SF] and sedative withdrawal [SW]), as well as outcome, were prospectively recorded. A total of 23.4% (119/509) of the admitted patients received MV >24h; 68.9% were males; age 57.0 (17.9) years; APACHE II score 18.8 (7.2); with a medical cause of admission in 53.9%. Half of them consumed at least one psychotropic agent (smoking 27.7%, HUA 25.2%; MPP 9.2%; and IP 7.6%). HUA patients more frequently required PS (86.7% vs. 64%; p2 sedatives (56.7% vs. 28.1%; p<0.02). HUA was associated to an eightfold (p<0.001) and fourfold (p<0.02) increase in SF and SW, respectively. In turn, the duration of MV and the stay in the ICU was increased by 151h (p<0.02) and 4.4 days (p<0.02), respectively, when compared with the non-HUA group. No differences were found in terms of mortality. HUA may be associated to a higher risk of SF and WS, and can prolong MV and the duration of stay in the ICU in critical patients. Early identification could allow the implementation of specific sedation strategies aimed at preventing these complications. Copyright © 2015 Elsevier España, S.L.U. and SEMICYUC. All rights reserved.

  5. Bibliography of Soviet Laser Developments, Number 86, November - December 1986.

    Science.gov (United States)

    1987-12-01

    Rudnitskaya, A.A.; Librovich, N.B.; Fialkov , Yu.Ya. (IKhF). Ion-molecular interactions in H(sub2)SO(sub4) - diethyl ether and H(sub2)SO(sub4... FIALKOV YU YA 94 GIPPIUS N A 104 DOLGOV-SAVEL’YEV G G 24 FILIMONOV D A 100 GIRDAUSKAS V V 64 DONRACHEV S 1 50 FILIPPOV 0 K 80 GIRENKO YU N 21

  6. 78 FR 44806 - Amendments to Regulation D, Form D and Rule 156

    Science.gov (United States)

    2013-07-24

    ... FURTHER INFORMATION CONTACT: Charles Kwon, Special Counsel or Ted Yu, Senior Special Counsel, Office of... Efficiency, Competition and Capital Formation X. Small Business Regulatory Enforcement Fairness Act XI...

  7. Summaries of Research, 1 July - 31 December 1965

    National Research Council Canada - National Science Library

    Watten, R

    1965-01-01

    ...: Intestinal parasites of aborigines (Yami) of Lan Yu (Orchid Island), NOTES ON SOME MALLOPHAGA FROM FORMOSAN MAMMALS, OBSERVATIONS ON THE BIONOMICS OF THE BITING MIDGE CULICOIDES ARAKAWAE (ARKAKAWA...

  8. Atherogenic Index of Plasma Predicts Hyperuricemia in Rural Population: A Cross-Sectional Study from Northeast China.

    Science.gov (United States)

    Chang, Ye; Li, Yuan; Guo, Xiaofan; Guo, Liang; Sun, Yingxian

    2016-09-02

    We aimed to determine the association of atherogenic index of plasma (AIP) with hyperuricemia (HUA) in the rural population of northeast China. This cross-sectional study was conducted in the rural areas of northeast China from January 2012 to August 2013, and the final analysis included data obtained form 5253 men and 6092 women. 1104 participants (9.7%) suffered from HUA. Spearman rank test showed that AIP was positively correlated with uric acid in both sexes (r = 0.310 for men and r = 0.347 for women, both p 0.21) risk. The prevalence of HUA increased with AIP. Multivariate logistic regression analysis showed that, compared to the low AIP group, participants in increased AIP group had a 2.536-fold risk for HUA (2.164-fold in male and 2.960-fold in female) after adjustment for covariates. Results of receiver operating characteristic curves showed that the area under the curve (95% confidence intervals) was 0.686 (0.665-0.707) for male and 0.730 (0.706-0.755) for female. We indicated that increased AIP was associated with higher serum uric acid levels and could be identified as an independent risk factor of HUA in the rural population of northeast China.

  9. Atherogenic Index of Plasma Predicts Hyperuricemia in Rural Population: A Cross-Sectional Study from Northeast China

    Directory of Open Access Journals (Sweden)

    Ye Chang

    2016-09-01

    Full Text Available We aimed to determine the association of atherogenic index of plasma (AIP with hyperuricemia (HUA in the rural population of northeast China. This cross-sectional study was conducted in the rural areas of northeast China from January 2012 to August 2013, and the final analysis included data obtained form 5253 men and 6092 women. 1104 participants (9.7% suffered from HUA. Spearman rank test showed that AIP was positively correlated with uric acid in both sexes (r = 0.310 for men and r = 0.347 for women, both p < 0.001. AIP was classified into three groups: the low (<0.11, the intermediate (0.11–0.21 and the increased (>0.21 risk. The prevalence of HUA increased with AIP. Multivariate logistic regression analysis showed that, compared to the low AIP group, participants in increased AIP group had a 2.536-fold risk for HUA (2.164-fold in male and 2.960-fold in female after adjustment for covariates. Results of receiver operating characteristic curves showed that the area under the curve (95% confidence intervals was 0.686 (0.665–0.707 for male and 0.730 (0.706–0.755 for female. We indicated that increased AIP was associated with higher serum uric acid levels and could be identified as an independent risk factor of HUA in the rural population of northeast China.

  10. Effects of urbanization on gaseous and particulate polycyclic aromatic hydrocarbons and polychlorinated biphenyls in a coastal city, China: levels, sources, and health risks.

    Science.gov (United States)

    Hong, Youwei; Chen, Jinsheng; Zhang, Fuwang; Zhang, Han; Xu, Lingling; Yin, Liqian; Chen, Yanting

    2015-10-01

    Gas/particle distributions of polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) were measured in Xiamen from May 2009 to March 2010 to evaluate the impacts of urbanization on the fate of persistent organic pollutants (POPs) in the atmospheric environment. In a newly developing area (NDA), the concentrations of 16 PAHs (gas + particle) were significantly higher than that a historically urbanized area (HUA) (p value <0.05), while the trend of 28 PCBs was reversed. Diagnostic ratios and principle component analysis (PCA) implied that atmospheric PAHs in the NDA were mainly derived from petrogenic combustion, including mixed sources of vehicle emissions, biomass burning and oil combustion, while pyrogenic combustion (e.g., traffic and coal combustion) was considered the major source of PAHs in the HUA. Atmospheric PCBs in both HUA and NDA were dominated by TriCBs and PeCBs related to the use of commercial mixtures (Aroclors 1242 and 1254). Based on the toxicological equivalent factor (TEF) approach, total benzo[a]pyrene equivalent values in the HUA and NDA were 1.12 and 2.02 ng m(-3), respectively, exceeding the standard threshold values (1.0 ng m(-3)) of China and WHO. Average daily intake of dioxin-like compounds was 0.2 pg kg(-1) day(-1) in the HUA, which are below the WHO tolerable daily intake level. The results showed that the contribution to the toxic equivalency (TEQ) was dominated by PCB169, PCB105, and PCB81.

  11. Localization and Specification of Copper Ions in Biofilms on Corroding Copper Surfaces.

    Science.gov (United States)

    1994-01-01

    Sao Paulo, Brazil: Aquatec Quimica : 1985). 256/3 5. H. Shih, F. Mansfeld, ASTM STP 1154, 174, Philadelphia, PA, 1992. 6. B. Little, P. Wagner, R...Pope, "A Study of Microbiologically Influenced Corrosion in Nuclear Power Plants and a Practical Guide for Countermeasures," Electric Power Research

  12. Surgical and medical treatment of ocular disease in a dog with Ehlers-Danlos syndrome.

    Science.gov (United States)

    Rasch, Søren N

    2017-06-01

    Correctional surgery was performed on a 3-year-old intact male shih tzu presenting with Ehlers-Danlos syndrome, ocular disease, and skin fold dermatitis. A one-year follow-up showed that no further clinical corrections were needed. Therefore, surgery could be considered in some canine patients with Ehlers-Danlos syndrome.

  13. (Chlorophyta) biomass production using Moringa oleifera Lam. leaf ...

    African Journals Online (AJOL)

    Chlorella sorokiniana Shih. et Krauss, a unicellular green alga was assayed to assess its to promotion potentials response of aqueous and ethanolic leaf extracts of Moringa oleifera Lam. C. sorokiniana grown in 200 ml aliquots of modified basal medium for two weeks: was treated with the aqueous and ethanolic extracts at ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Chi-Fang Chin1 Arthur Chun-Chieh Shih2 Kuo-Chin Fan1 3. Department of Computer Science and Information Engineering, National Central University, Chung-Li, Taiwan; Institute of Information Science, Academia Sinica, Taipei, Taiwan; Department of Informatics, Fo Guang Univeristy, Ilan, Taiwan ...

  15. Anti-inflammatory Effects of Magnolia sieboldii Extract in ...

    African Journals Online (AJOL)

    Hao Li4 and Kang-Duk Choi1*. 1Genomic ... Methods: The whole plant of M. sieboldii was extracted with methanol at room temperature. The in vitro ... action of M. sieboldii in inflammation. Magnolia ..... Shih HC, Hwang TL, Chen HC, Kuo PC, Lee EJ, Lee. KH, Wu TS. ... Fu JY, Masferrer JL, Seibert K, Raz A, Needleman P.

  16. The SDF-1-CXCR4 Axis Functions Through p38-MAPK Signaling to Drive Breast Cancer Progression and Metastasis

    Science.gov (United States)

    2009-09-01

    2002). Rubin JB, Kung AL, Klein RS, Chan JA, Sun Y, Schmidt K, Kieran MW, Luster AD, Segal RA.A small-molecule antagonist of CXCR4 inhibits... Melanie H. Howell, Michelle Lacey, Betty Y. Shih, Carol Carter-Wientjes, Thomas E. Cleveland, John A. McLachlan, Thomas E. Wiese, Barbara S. Beckman

  17. A case of non-regenerative immune-mediated anemia treated by ...

    African Journals Online (AJOL)

    A 12-year-old female Shih Tzu dog was referred with diarrhea. Hematological examination indicated severe nonregenerative anemia. Bone marrow aspiration smears and core biopsy specimens revealed normal bone marrow. Based on those results, non-regenerative immune mediated anemia was diagnosed. The dog ...

  18. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. W-P Sung. Articles written in Sadhana. Volume 34 Issue 3 June 2009 pp 421-437. A model for signal processing and predictive control of semi-active structural control system · M-H Shih W-P Sung Ching-Jong Wang · More Details Abstract Fulltext PDF. The theory for structural control has been ...

  19. Shigellosis

    Science.gov (United States)

    ... by Shigella (pronounced: shih-GEL-uh) bacteria. The bacteria produce toxins that can attack the lining of the ... fluids and may prescribe antibiotics to treat shigellosis. Antibiotics can help you recover faster and prevent the bacteria from spreading to other people. Most doctors suggest ...

  20. Metastable Supersymmetry Breaking in a Cooling Universe

    International Nuclear Information System (INIS)

    Kaplunovsky, Vadim S.

    2007-01-01

    I put metastable supersymmetry breaking in a cosmological context. I argue that under reasonable assumptions, the cooling down early Universe favors metastable SUSY-breaking vacua over the stable supersymmetric vacua. To illustrate the general argument, I analyze the early-Universe history of the Intriligator-Seiberg-Shih model

  1. Life or death? A Physiogenomic Approach to Understand Individual Variation in Responses to Hemorrhagic Shock

    Science.gov (United States)

    2011-01-01

    2009, 234, 1503-1510. [34] Fang, J. F.; Shih, L. Y.; Yuan, K. C.; Fang, K. Y.; Hwang, T. L.; Hsieh, S. Y. Proteomic analysis of post-hemorrhagic...resistant and susceptible barley lines during interaction with the powdery mildew fungus . Plant Mol. Biol., 2001, 47, 739-748. [96] Harris, N. S

  2. The Effect of Spray Initial Conditions on Heat Release and Emissions in LDI CFD Calculations (Preprint)

    Science.gov (United States)

    2008-06-01

    Shih, T.-H., Povinelli , L. A., Liu, N.-S and Chen, K.-H., (2000), “Generalized Wall Function for...J. Marek, T. D. Smith, N.-S. Liu, and L. A. Povinelli (NASA, Glenn Research Center, Cleveland, OH, “A Study of Hydrogen/Air Combustor Using NCC

  3. Further genetic localization of the transforming sequences of the p21 v-ras gene of Harvey murine sarcoma virus

    DEFF Research Database (Denmark)

    Willumsen, B M; Ellis, R W; Scolnick, E M

    1984-01-01

    , DNA sequence analysis has found a single open reading frame large enough to encode the viral p21 (R. Dhar, R. W. Ellis, T. Y. Shih, S. Oroszlan, B. Shapiro, J. Maizel, D. Lowy, and E. M. Scolnick, Science 217:934-937, 1982). There are three potential in-frame ATG initiation codons at the 5' end...

  4. East Asia: Southeast Asia

    Science.gov (United States)

    1990-09-05

    supporting role in the founding of Malaysia. Some people describe their role as having a position but having no authority. During the cogon grass campaign...Pian Hon Yun Shih-chin’s luck was much greater than Kuo Wei- chieh’s. Although both are deputy ministers, their grass - roots power is weak. Kuo

  5. Effect of aging on copper nanoparticles synthesized by pulsed laser ...

    Indian Academy of Sciences (India)

    Administrator

    2009-06-23

    Jun 23, 2009 ... Hsieh C T, Chen J M, Lin H H and Shih H C 2003 Appl. Phys. Lett. 83 3383. Hsieh J H, Kuo P W, Peng K C, Liu S J, Hsueh J D and Chang. S C 2008 Thin ... Jung J H, Kim T W, Song M S, Kim Y H and Yoo K H 2007. J. Appl.

  6. Genetics Home Reference: monoamine oxidase A deficiency

    Science.gov (United States)

    ... Cases O, Seif I, Grimsby J, Gaspar P, Chen K, Pournin S, Müller U, Aguet M, Babinet C, Shih JC, et al. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. Science. 1995 Jun 23;268(5218):1763-6. Citation on ...

  7. Determinants of Computer and Internet Adoption and Use in ...

    African Journals Online (AJOL)

    centres and promote the training of youths and social networks. Keywords: ICT ... factors are underscored in studies in developing countries(Shih and. Venkatesh ... mentions several obstacles to ICT development in cities and the role of these ... Cameroon as the towns of the eight other regions including the Centre that.

  8. The Attention Cascade Model and Attentional Blink

    Science.gov (United States)

    Shih, Shui-I

    2008-01-01

    An attention cascade model is proposed to account for attentional blinks in rapid serial visual presentation (RSVP) of stimuli. Data were collected using single characters in a single RSVP stream at 10 Hz [Shih, S., & Reeves, A. (2007). "Attentional capture in rapid serial visual presentation." "Spatial Vision", 20(4), 301-315], and single words,…

  9. Frequency Conversion of Single Photons: Physics, Devices, and Applications

    Science.gov (United States)

    2012-07-01

    Anton Zeilinger , Alexan- der V. Sergienko, and Yanhua Shih. New high-intensity source of polarization- entangled photon pairs. Physical Review Letters...interface. Nature, 437(7055):116–120, 2005. [36] S. Ramelow, A. Fedrizzi, A. Poppe, N. K. Langford, and A. Zeilinger . Polarization-entanglement-conserving

  10. Browse Title Index

    African Journals Online (AJOL)

    Items 8801 - 8850 of 11090 ... A Mansseri-Lamrioui, A Louerguioui, J Bonaly, ... Vol 13, No 53 (2014), Promoting increased Chlorella sorokiniana Shih. et Krauss (Chlorophyta) biomass ... Vol 16, No 3 (2017), Protection of Lactobacillus acidophilus under in vitro ... Araújo Campos, Pedro Martins Ribeiro Júnior, Fabrício Rabelo ...

  11. Preparation of arginine–glycine–aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization

    Directory of Open Access Journals (Sweden)

    Chang CY

    2016-12-01

    Full Text Available Che-Yi Chang,1,2,* Ming-Chen Wang,2,* Takuya Miyagawa,1 Zhi-Yu Chen,1 Feng-Huei Lin,3,4 Ko-Hua Chen,5,6 Guei-Sheung Liu,7 Ching-Li Tseng1 1Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 2Department of Biomedical Engineering, Chung Yuan Christian University, Taoyuan, 3Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Zhunan, 4Institute of Biomedical Engineering, National Taiwan University, 5Department of Ophthalmology, Taipei Veterans General Hospital, 6Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 7Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC, Australia *These authors contributed equally to this work Abstract: Neovascularization (NV of the cornea can disrupt visual function, causing ocular diseases, including blindness. Therefore, treatment of corneal NV has a high public health impact. Epigalloccatechin-3-gallate (EGCG, presenting antiangiogenesis effects, was chosen as an inhibitor to treat human vascular endothelial cells for corneal NV treatment. An arginine–glycine–aspartic acid (RGD peptide–hyaluronic acid (HA-conjugated complex coating on the gelatin/EGCG self-assembly nanoparticles (GEH-RGD NPs was synthesized for targeting the αvβ3 integrin on human umbilical vein endothelial cells (HUVECs in this study, and a corneal NV mouse model was used to evaluate the therapeutic effect of this nanomedicine used as eyedrops. HA-RGD conjugation via COOH and amine groups was confirmed by 1H-nuclear magnetic resonance and Fourier-transform infrared spectroscopy. The average diameter of GEH-RGD NPs was 168.87±22.5 nm with positive charge (19.7±2 mV, with an EGCG-loading efficiency up to 95%. Images of GEH-RGD NPs acquired from transmission electron microscopy showed a

  12. Importance-Performance Analysis of Personal Health Records in Taiwan: A Web-Based Survey.

    Science.gov (United States)

    Rau, Hsiao-Hsien; Wu, Yi-Syuan; Chu, Chi-Ming; Wang, Fu-Chung; Hsu, Min-Huei; Chang, Chi-Wen; Chen, Kang-Hua; Lee, Yen-Liang; Kao, Senyeong; Chiu, Yu-Lung; Wen, Hsyien-Chia; Fuad, Anis; Hsu, Chien-Yeh; Chiu, Hung-Wen

    2017-04-27

    participants, 56.6%), with a monthly income of less than NT $30,000 (230 of 350 participants, 65.7%), and living in the North Taiwan (236 of 350 participants, 67.4%), with a good self-identified health status (171 of 350 participants, 48.9%). After performing the importance-performance analysis, we found the following: (1) instead of complex functions, people just want to have a platform that can let them integrate and manage their medical visit, health examination, and life behavior records; (2) they do not care whether their PHR is shared with others; and (3) most of the participants think the system security design is not important, but they also do not feel satisfied with the current security design. Overall, the issues receiving the most user attention were the system functions, circulation, integrity, ease of use, and continuity of the PHRs, data security, and privacy protection. ©Hsiao-Hsien Rau, Yi-Syuan Wu, Chi-Ming Chu, Fu-Chung Wang, Min-Huei Hsu, Chi-Wen Chang, Kang-Hua Chen, Yen-Liang Lee, Senyeong Kao, Yu-Lung Chiu, Hsyien-Chia Wen, Anis Fuad, Chien-Yeh Hsu, Hung-Wen Chiu. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 27.04.2017.

  13. The 2nd International Conference on Agricultural and Biological Sciences (ABS 2016

    Directory of Open Access Journals (Sweden)

    Lei Pei

    2016-10-01

    Salvia of Labiatae in China Xiaojuan Li, Ning Xu, Guofu Zhou, Ming Wan, Qi Lin, Fanyun Meng, Jianxiu Li 15 Three pulling resistance models of pioneer plant in landslide area Yichang Chen, Koayung Yu, Chunpin Chang 16 The comparison of physiological and biochemical mechanisms of Reaumuria soongorica and Salsola passerine in different growth pattern Zijuan Zhou, Peixi Su, Rui Shi, Tingting Xie 17 Resources use efficiency of the cosmopolitan plant Potentilla anserina L. in different alpine habitats in China Rui Shi, Peixi Su, Zijuan Zhou 18 Cloning of PPDK gene from Red Amaranand transformation of Alfalfa Xuelan Liu, Yan Zhang, Xiangfa Wei 19 Variation and cluster analysis of morphological characters and nutrient content of Chucrasia tabularis seed Chong Wu, Yanlei Yin, Lijuan Feng, Xuemei Yang, Fei Wang 20 Effect of the planting density of the areca nut on the growth of intercropped Vanilla Hua Wang, Huifa Zhuang, Zihui Zhu, Hui Wang

  14. Role of estrogen in lung cancer based on the estrogen receptor-epithelial mesenchymal transduction signaling pathways

    Directory of Open Access Journals (Sweden)

    Zhao XZ

    2015-10-01

    Full Text Available Xiao-zhen Zhao,1,* Yu Liu,1,* Li-juan Zhou,1,* Zhong-qi Wang,1 Zhong-hua Wu,2 Xiao-yuan Yang31Department of Tumor, Longhua Hospital, 2Center of Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 3Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA*These authors contributed equally to this workBackground/aim: Estrogen is reported to promote the occurrence and development of several human cancers. Increasing evidence shows that most human lung tumors exert estrogen receptor expression. In the present study, we investigated the underlying mechanism of estrogen effect in lung cancer through estrogen receptor-epithelial–mesechymal-transition signaling pathways for the first time.Materials and methods: A total of 36 inbred C57BL/6 mice (18 male and 18 female were injected subcutaneously with human lung adenocarcinoma cell line, Lewis. After the lung tumor model was established, mice with lung adenocarcinoma were randomly divided into three groups for each sex (n=6, such as vehicle group, estrogen group, and estrogen plus tamoxifen group. The six groups of mice were sacrificed after 21 days of drug treatment. Tumor tissue was stripped and weighed, and tumor inhibition rate was calculated based on average tumor weight. Protein and messenger RNA (mRNA expressions of estrogen receptor α (ERα, estrogen receptor β (ERβ, phosphatidylinositol 3'-kinase (PI3K, AKT, E-cadherin, and vimentin were detected in both tumor tissue and lung tissue by using immunohistochemistry and real-time reverse transcription-polymerase chain reaction.Results: 1 For male mice: in the estrogen group, estrogen treatment significantly increased ERα protein and mRNA expressions in tumor tissue and protein expression of PI3K, AKT, and vimentin in both tumor tissue and lung tissue compared with the vehicle-treated group. Besides, m

  15. Nuclear Structure in China 2010

    Science.gov (United States)

    Bai, Hong-Bo; Meng, Jie; Zhao, En-Guang; Zhou, Shan-Gui

    2011-08-01

    fragmentation at the intermediate energy / C. W. Ma ... [et al.].Systematic study of spin assignment and dynamic moment of inertia of high-j intruder band in [symbol]In / K. Y. Ma ... [et al.] -- Signals of diproton emission from the three-body breakup channel of [symbol]Al and [symbol]Mg / Ma Yu-Gang ... [et al.] -- Uncertainties of Th/Eu and Th/Hf chronometers from nucleus masses / Z. M. Niu ... [et al.] -- The chiral doublet bands with [symbol] configuration in A[symbol]100 mass region / B. Qi ... [et al.] -- [symbol] formation probabilities in nuclei and pairing collectivity / Chong Qi -- A theoretical prospective on triggered gamma emission from [symbol]Hf[symbol] isomer / ShuiFa Shen ... [et al.] -- Study of nuclear giant resonances using a Fermi-liquid method / Bao-Xi Sun -- Rotational bands in doubly odd [symbol]Sb / D. P. Sun ... [et al.] -- The study of the neutron N=90 nuclei / W. X. Teng ... [et al.] -- Dynamical modes and mechanisms in ternary reaction of [symbol]Au+[symbol]Au / Jun-Long Tian ... [et al.] -- Dynamical study of X(3872) as a D[symbol] molecular state / B. Wang ... [et al.] -- Super-heavy stability island with a semi-empirical nuclear mass formula / N. Wang ... [et al.] -- Pseudospin partner bands in [symbol]Sb / S. Y. Wang ... [et al.] -- Study of elastic resonance scattering at CIAE / Y. B. Wang ... [et al.] -- Systematic study of survival probability of excited superheavy nuclei / C. J. Xia ... [et al.] -- Angular momentum projection of the Nilsson mean-field plus nearest-orbit pairing interaction model / Ming-Xia Xie ... [et al.] -- Possible shape coexistence for [symbol]Sm in a reflection-asymmetric relativistic mean-field approach / W. Zhang ... [et al.] -- Nuclear pairing reduction due to rotation and blocking / Zhen-Hua Zhang -- Nucleon pair approximation of the shell model: a review and perspective / Y. M. Zhao ... [et al.] -- Band structures in doubly odd [symbol]I / Y. Zheng ... [et al.] -- Lifetimes of high spin states in [symbol]Ag / Y

  16. Phase I study of anticolon cancer humanized antibody A33.

    Science.gov (United States)

    Welt, Sydney; Ritter, Gerd; Williams, Clarence; Cohen, Leonard S; John, Mary; Jungbluth, Achim; Richards, Elizabeth A; Old, Lloyd J; Kemeny, Nancy E

    2003-04-01

    Humanized A33 (huA33; IgG1) monoclonal antibody detects a determinant expressed by 95% of colorectal cancers and can activate immune cytolytic mechanisms. The present study was designed to (a) define the toxicities and maximum tolerated dose of huA33 and (b) determine huA33 immunogenicity. Patients (n = 11) with advanced chemotherapy-resistant colorectal cancer received 4-week cycles of huA33 at 10, 25, or 50 mg/m(2)/week. Serum samples were analyzed using biosensor technology for evidence of human antihuman antibody (HAHA) response. Eight of 11 patients developed a HAHA response. Significant toxicity was limited to four patients who developed high HAHA titers. In two of these cases, infusion-related reactions such as fevers, rigors, facial flushing, and changes in blood pressure were observed, whereas in the other two cases, toxicity consisted of skin rash, fever, or myalgia. Of three patients who remained HAHA negative, one achieved a radiographic partial response, with reduction of serum carcinoembryonic antigen from 80 to 3 ng/ml. Four patients had radiographic evidence of stable disease (2, 4, 6, and 12 months), with significant reductions (>25%) in serum carcinoembryonic antigen levels in two cases. The complementarity-determining region-grafted huA33 antibody is immunogenic in the majority of colon cancer patients (73%). HAHA activity can be measured reproducibly and quantitatively by BIACORE analysis. Whereas the huA33 construct tested here may be too immunogenic for further clinical development, the antitumor effects observed in the absence of antibody-mediated toxicity and in this heavily pretreated patient population warrant clinical testing of other IgG1 humanized versions of A33 antibody.

  17. ALK and TGF-Beta Resistance in Breast Cancer

    Science.gov (United States)

    2017-10-01

    Award Number: W81XWH‐15‐1‐0650 TITLE: ALK and TGF-Beta Resistance in Breast Cancer PRINCIPAL INVESTIGATOR: Xin-Hua Feng CONTRACTING...and TGF-Beta Resistance in Breast Cancer 5b. GRANT NUMBER W81XWH‐15‐1‐0650 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Xin-Hua Feng...response is a hallmark in human cancer . However, the mechanisms underlying TGF- resistance in breast cancer have not been elucidated. Anaplastic

  18. X-ray attenuation coefficients and photoelectric cross sections of Cu, Fe and Sn for the energy range 3-29 KeV

    International Nuclear Information System (INIS)

    Wang Dachun; Yang Hua; Luo Pingan; Ding Xunliang; Wang Xinfu; Zhou Hongyu; Shen Xinyin; Zhu Guanghua

    1991-08-01

    The document contains the following two papers: X-ray attenuation coefficient and photoelectric cross sections of Sn for the Energy Range 3.3 KeV to 29.1 KeV - by Wang Dachun, Yang Hua and Luo Pingan. X-ray attenuation coefficients and photoelectric cross sections of Cu and Fe for the range 3 KeV to 29 KeV - by Wang Dachun, Ding Xunliang, Wang Xinfu, Yang Hua, Zhou Hongyu, Shen Xinyin and Zhu Guanghua. A separate abstract was prepared for each of these papers. Refs, figs and tabs

  19. Finnish Play Becomes Chinese Local Opera

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    IN the fall of 1992 an unusualpremiere took place in Xi′an:Totisesti totisesti,adapted from aFinnish stage play,was performed asan opera in Chinese by the HuaOpera Troupe,a part of the ShaanxiOpera Research Institute.Ms.InkeriKilpinen,the playwright,and Ms.Leena Laulajainen,vice-chairman ofFinland Writers′Association,cameto see the performance.Hua opera,also known as“Wanwan Opera,”is one of the localforms of opera in Shaanxi Province.It was originally performed in theform of shadow play,and was for-

  20. Technical and Economic Considerations in the Preservation of Meats and Poultry by Ionizing Radiation; Considerations d'Ordre Technique et Economique sur la Conservation des Viandes et de la Volaille par les Rayonnements Ionisants; Tekhnicheskie i ehkonomicheskie soobrazheniya otnositel'no'konservatsii myasa i ptitsy s pomoshch'yu ioniziruyushchikh izluchenij; Consideraciones Tecnicas y Economicas Acerca de la Conservacion de Carnes y Volateria por Irradiacion

    Energy Technology Data Exchange (ETDEWEB)

    Urbain, W. M. [Department of Food Science, Michigan State University, East Lansing, MI (United States)

    1966-11-15

    Radiation-sterilized meats and poultry can be of a quality better than that obtained with thermal processing. Where the normal method of preservation of meat and poultry during distribution is refrigeration, radiation at sterilizing levels is not likely to replace it. A principal reason for this is cost. In such a civilian market, radiation-sterilized meats will serve primarily as convenience foods. Radiation-pasteurization could provide a significant product life extension for fresh meats and poultry by delaying microbial spoilage, especially in the centralized preparation of retail cuts. Other factors of meat spoilage of a chemical or physical nature, however, are not controlled by radiation; and until they are, there is no real marketing value in the use of radiation. For fresh or frozen poultry there is the possibility of Salmonella control, should this be needed. Costs for sterilization and pasteurization are estimated and are presented in a form to permit selection of specific conditions within a range for certain important variables. From a commercial viewpoint, it is important to determine the consumer acceptance of radiation- sterilized meats and poultry. The usual approach to such a determination is to market the products in question in a limited manner and to measure the acceptance under such market conditions. To accomplish this with radiation-sterilized foods, the next step appears to be to obtain a production capability to supply the products for test marketing. (author) [French] Les viandes et la volaille sterilisees par les rayonnements peuvent etre de meilleure qualite que celle obtenue par un traitement thermique; Lorsqu'on utilise la refrigeration comme methode normale de conservation de la viande et de la volaille en cours de distribution, il est peu probable qu'on lui substitue l'irradiation a des doses sterilisantes. La principale raison eri est le cout eleve de l'irradiation. Dans un marche destine a repondre aux besoins civils, les viandes radiosterilisees seront utilisees comme appoint. La radiopasteurisation pourrait prolonger sensiblement la duree de conservation des viandes et volailles fraiches en retardant la deterioration par les bacteries, notamment dans les grandes installations de debitage pour la vente au detail. Par contre, les rayonnements n'influent pas sur certains autres facteurs chimiques ou physiques de la corruption des viandes; tant que cela ne sera pas le cas, l'emploi des rayonnements ne presentera pas d'interet commercial reel. Dans le cas de la volaille fraiche ou congelee, on pourrait, le cas echeant, appliquer un traitement contre la Salmonella. Des estimations des prix de revient de la radiosterilisation et de la pasteurisation sont presentees de maniere a permettre le choix de conditions particulieres et une certaine latitude pour tenir compte de variations importantes. Du point de vue commercial, il importe de savoir dans quelle mesure le.consommateur accepte les viandes et la volaille radiosterilisees. La methode habituelle a cette fin consiste a ne mettre sur le marche qu'une quantite limitee des produits en question et a ' mesurer' l'acceptation dans de telles conditions du marche. S'il s'agit de denrees alimentaires radiosterilisees, il faut encore assurer une capacite de production suffisante pour l'essai de commercialisation. (author) [Spanish] La calidad de las carnes y la volateria radioesterilizadas puede ser. superior a la que se obtiene sometiendolas a tratamiento termico. Cuando la refrigeracion es el metodo normalmente empleado para conservar la carne y la volateria durante su distribucion, hay pocas probabilidades de que sea sustituida por la radioesterilizacion. La razon principal estriba en los costos. En estas condiciones, las carnes radioesterilizadas se utilizaran en el mercado sobre todo como recurso excepcional. La radiopasteurizacion podria prolongar considerablemente el periodo de conservacion de las carnes y la volateria frescas, puesto que retarda la accion destructiva de los microbios, sobre todo en la preparacion centralizada de piezas para detallistas. Pero las radiaciones no eliminan otros agentes de naturaleza fisica o quimica tambien nocivos para la carne; mientras dure tal situacion, la irradiacion carece de autentico valor comercial. En lo que se refiere a la volateria fresca o congelada, las radiaciones, si es necesario, permiten eliminar la Salmonella. Se calculan los costos de la esterilizacion y de la pasterizacion, y se presentan de forma que permite seleccionar condiciones especificas en un intervalo de valores de ciertas variables importantes. Desde el punto de vista comercial, es importante conocer la aceptacion que tendran las carnes y la volateria radioesterilizadas. Para ello el procedimiento habitualmente seguido consiste en poner en venta una cantidad limitada de productos y observar su acogida en el mercado. Es por consiguiente necesario lograr una capacidad de produccion adecuada a las necesidades de ese estudio. (author) [Russian] Mjaso i ptica, sterilizovannye s pomoshh'ju izluchenij, mogut byt' luchshego kachestva po sravneniju s tem, kotoroe dostigaetsja termicheskoj obrabotkoj. Tam, gde obychnym metodom konservirovanija mjasa i pticy vo vremja raspredelenija javljaetsja zamorazhivanie, obluchenie, dostigajushhee urovnej sterilizacii, vrjad li zamenit jetot metod. Glavnaja prichina jetogo zakljuchaetsja v stoimosti. Na takom rynke sterilizovannoe s pomoshh'ju obluchenija mjaso budet sluzhit' glavnym obrazom v kachestve polufabrikata . Pasterizacija s pomoshh'ju obluchenija mogla by znachitel'no uvelichit' srok sohrannosti svezhego mjasa i pticy putem predohranenija ih ot porchi mikrobami, osobenno pri centralizovannoj razdelke dlja prodazhi v roznicu. Tem ne menee obluchenie ne ustranjaet drugie prichiny porchi mjasa, kotorye imejut himicheskij ili fizicheskij harakter; do teh por, poka jeti prichiny sushhestvujut, primenenie obluchenija ne budet davat' zhelaemyh jeffektov pri realizacii. V sluchae neobhodimosti dlja svezhej ili morozhenoj pticy mozhno primenit' kontrol' v otnoshenii salmonelly. Orientirovochno opredeleny rashody, svjazannye so sterilizaciej i pasterizaciej, kotorye predstavleny v takoj forme, kotoraja pozvoljaet vybrat' konkretnye uslovija v ramkah opredelennyh osnovnyh peremennyh. S kommercheskoj tochki zrenija mozhno opredelit' priemlemost' dlja potrebitelja sterili zovannyh s pomoshh'ju obluchenija mjasa i pticy. Obychnym sposobom reshenija takogo voprosa javljaetsja razmeshhenie na rynke opredelennyh produktov v ogranichennyh kolichestvah i oprede lenie intensivnosti sprosa na nih v takih uslovijah rynka. Sledujushhim shagom na puti realizacii sterilizovannyh s pomoshh'ju obluchenija produktov javitsja, po-vidimomu, dostizhenie proizvodstvennyh vozmozhnostej dlja postavok produktov dlja kontrol'noj realizacii. (author)

  1. Determination of D{sub 2}O-2% Enriched Uranium Lattice Parameters by Means of a Critical System; Determination des Parametres d'un Reseau Uranium Enrichi a 2%-Eau Lourde au Moyen d'un Ensemble Critique; Opredelenie s pomoshch'yu kriticheskoj sistemy parametrov reshetki s 2%-nym obog ashcheniem Urana i s zamedlitelem D{sub 2}O; Determinacion, Mediante un Conjunto Critico, de los Parametros de un Reticulado de D{sub 2}O y Uranio Enriquecido al 2%

    Energy Technology Data Exchange (ETDEWEB)

    Raisic, N.; Takac, S.; Markovic, H.; Bosevski, T. [Boris Kidric Institute of Nuclear Sciences, Belgrade, Yugoslavia (Serbia)

    1964-02-15

    The paper describes a series of experiments performed to determine the basic parameters of a D{sub 2}O-2% enriched-uranium lattice. The fuel elements were hollow cylinders, canned in aluminium and wetted by heavy water both on the inside and outside. The experiments were performed on the RB critical assembly of the Boris Kidric Institute of Nuclear Sciences in Belgrade. The clean geometry of this system enables a rather simple theoretical interpretation of experimental results, and straightforward comparison with two-group diffusion-theory calculations. Measurements performed for ten different lattice configurations included determination of buckling, water-level reactivity coefficient and disadvantage factors for thermal-and epithermal-neutron flux inside a reactor cell. Techniques for these measurements are described. The experimental data are then used to derive the lattice parameters defined by the four-factor formula and two-group diffusion-theory treatment of the reactor core. The results are compared with the standard calculations of the same parameters for measured lattice configurations. Deviations are found in the value of n and resonance integral for U{sup 238}. In conclusion, an analysis is made of the usefulness and accuracy of information obtained from critical experiments for design and exploitation of a research reactor, composed of D{sub 2}O and enriched uranium. (author) [French] Les auteurs decrivent une serie d'experiences qu'ils ont faites pour determiner les parametres fondamentaux d'un reseau uranium enrichi a 2%-eau lourde. Les elements combustiblesetaient des cylindres creux, gaines d'aluminium et baignant'dans l'eau lourde, a l'interieur comme a l'exterieur. Ils se sont servis de l'assemblage critique RB de l'Institut Boris Kidric des sciences nucleaires a Belgrade. La geometrie de cet assemblage non empoisonne a permis d'interpreter le resultat experimental a l'aide d'une theorie assez simple et de le comparer directement aux calculs faits par la theorie de la diffusion a deux groupes. Les mesures, pour dix configurations de reseau differentes, comportaient la determination du laplacien, du coefficient du niveau d'eau et des facteurs de desavantage pour le flux de neutrons thermiques et epither- miques a l'interieur d'une cellule. Le memoire decrit les methodes de mesure. Les auteurs utilisent ensuite les donnees experimentales pour en deduire les parametres de reseau determines par le calcul du coeur du reacteur au moyen de la formule des quatre facteurs et dans une theorie de diffusion a deux groupes. Ils comparent ces resultats avec les calculs classiques des memes parametres pour des configurations de reseau ayant fait l'objet de mesures. Ils ont constate des ecarts dans la valeur de n et de l'integrale de resonance pour {sup 238}U. En conclusion, les auteurs analysent l'utilite et l'exactitude des informations recueillies a l'aide des montages critiques en vue de l'etude et de l'exploitation d'un reacteur de recherche a uranium enrichi et eau lourde. (author) [Spanish] En la memoria se describe una serie de experimentos efectuados con objeto de determinar los parametros basicos de un reticulado de D{sub 2}O y uranio enriquecido al 2% Los elementos combustibles consistian en cilindros huecos, revestidos de aluminio, con agua pesada en el interior y en el exterior. Los experimentos se realizaron en el conjunto critico RB del Instituto de Ciencias Nucleares 'Boris Kidric' (Belgrado). La geometria sencilla de este conjunto facilita la interpretacion teorica de los resultados experimentales, asi como la comparacion directa con calculos efectuados segun la teoria de difusion de dos grupos. Entre las mediciones efectuadas para diez configuraciones diferentes de reticulado, figuraban la determinacion del laplaciano, del coeficiente de reactividad del nivel de agua y de los factores de desventaja para un flujo de neutrones termico y epitermico dentro de una celda del reactor. En la memoria se describen las tecnicas utilizadas en las mediciones. Los datos experimentales sirvieron a continuacion para deducir los parametros del reticulado, dennidos por la formula de cuatro factores y el estudio matematico del cuerpo del reactor con arreglo a la teoria de difusion de dos grupos. Los resultados obtenidos se comparan con los valores corrientemente asignados a los mismos parametros para configuraciones de reticulados medidos. Se presentan las desviaciones halladas en el valor de n y en la integral de resonancia para el {sup 238}U. En conclusion, se analiza la utilidad y precision de los datos obtenidos con los experimentos criticos para la construccion y explotacion de un reactor de investigacion de D{sub 2}O y uranio enriquecido. (author) [Russian] Daetsja opisanie serii opytov, vypolnennyh s cel'ju opredelenija osnovnyh parametrov reshetki s 2%-nym obogashheniem urana i s zamedlitelem v vide D{sub 2}O. Toplivnye jelementy predstavljali soboj polye cilindry, pokrytye aljuminiem i smochennye kak snaruzhi, tak i iznutri vodoj. Opyty provodilis' na kriticheskoj sborke RB Instituta jadernyh nauk im. Boris Kidric v Belgrade. Udobooptekaemaja geometricheskaja forma jetoj sistemy daet vozmozhnost' sravnitel'no prosto teoreticheski ob'jasnit' rezul'taty opytov i provesti neposredstvennoe gotovoe sravnenie s raschetami dvuhgruppovoj teorii diffuzii. Izmerenija, vypolnennye dlja desjati razlichnyh konfiguracij reshetki, vkljuchali opredelenie laplasiana, kojefficienta reaktivnosti urovnja vody i blok-jeffekta dlja potoka teplovyh i nadteplovyh nejtronov vnutri kamery reaktora. Opisyvaetsja metodika ctih izmerenij. Dannye opytov ispol'zujutsja dlja vyvedenija parametrov reshetki, opredeljaemyh po formule chetyreh somnozhitelej i pri primenenii k aktivnoj zone reaktora dvuhgruppovoj teorii diffuzii. Rezul'taty sravnivajutsja so standartnymi raschetami teh zhe parametrov dlja izmerjaemyh konfiguracij reshetki. Otmechajutsja otklonenija v velichine p i rezonansnogo integrala U-238. V zakljuchenie provoditsja analiz poleznosti i tochnosti poluchennoj v re zul'tate provedenija kriticheskih jeksperimentov informacii dlja proektirovanija i jekspluatacii issledovatel'skogo reaktora ja obogashhennom urane s tjazhelovodnym zamedlitelem. (author)

  2. A Procedure for the Determination of Alpha-Emitting Plutonium in Urine Using a Solid-State Counter; Methode de Determination du Plutonium Emetteur Alpha Present dans l'Urine, au Moyen d'un Compteur a Semi-Conducteurs; Metod opredeleniya al'fa-izlucheniya plutoniya v moche s pomoshch'yu poluprovodnikovogo schetchika; Procedimiento para Determinar la Actividad Alfa del Plutonio en la Orina con Ayuda de un Contador de Estado Solido

    Energy Technology Data Exchange (ETDEWEB)

    Sandalls, F. J.; Morgan, A. [Health Physics and Medical Division, Atomic Energy Research Establishment, Harwell (United Kingdom)

    1964-10-15

    A method for the routine determination of alpha-emitting plutonium in urine is described. In evolving this procedure various techniques for concentrating, purifying and electro depositing plutonium were compared, and these investigations are summarized. In the procedure finally adopted, urine is wet-ashed and the residue dissolved in hydrochloric acid. Plutonium (IV) is co-precipitated with iron cupferride from this solution and extracted into chloroform. After evaporation of the chloroform, the residue is oxidized, dissolved in hydrochloric acid and the iron extracted into di-isopropyl ether. The aqueous phase containing the plutonium is evaporated and dissolved in an acid ammonium sulphate solution from which the plutonium is electrodeposited onto stainless steel. Quantitative recoveries are obtained over the electrodeposition stage and on overall recovery of 84 {+-} 7%. The electrodeposited plutonium is counted with a solid-state (silicon junction diode) detector in a counter developed for this purpose. The low inherent background of this type of counter is effectively reduced still further by counting only those alpha particles with energy in the 4.2 - 5.4 MeV range. The good resolution which can be obtained with thin electrodeposited sources of plutonium enables this narrow channel to be used with only small losses in counting efficiency. By counting over this restricted energy range, the blank activity arising from reagents and incomplete removal of alpha-emitting contaminants in urine is also reduced by a factor of two, to just over 0.01 pc/24-h sample. The limit of detection with this method is about 0.025 pc of Pu{sup 239}. (author) [French] Les auteurs exposent une methode pour la determination courante du plutonium emetteur alpha present dans l'urine. Pour mettre au point cette methode, ils ont compare diverse procedes de concentration, de purification et de depot electrolytique du plutonium; les resultats de ces recherches sont resumes dans le memoire. La methpde qu'ils ont finalement adoptee consiste a incinerer l'urine et a dissoudre le residu dans de l'acide chlorhydrique. A partir de cette solution,' le plutonium (IV) est coprecipite avec du cupferrate de fer et extrait au moyen de chloroforme. Apres evaporation de celui-ci, le residu est oxyde et dissous dans l'acide chlorhydrique, puis le fer est extrait au moyen d'ether di-isopropy- lique. La phase aqueuse contenant le plutonium est evaporee et dissoute dans une solution de sulfate acide d'ammonium, d'ou le plutonium est depose par electrolyse sur de l'acier inoxydable. Au stade du depot . electrolytique, on recueille dans l'ensemble 84 {+-} 7% du plutonium contenu. Le plutonium depose par electrolyse est mesure au moyen d'un detecteur a semi-conducteur (diode a jonction au silicium) dans un compteur concu a cette fin. Le faible mouvement propre de ce type de compteur est encore efficacement reduit si l'on ne compte que les particules alpha ayant des energies comprises entre 4,2 et 5,4 MeV. La bonne resolution que l'on peut obtenir avec de minces couches de plutonium deposees par electrolyse permet d'utiliser ce canal etroit en ne faisant que de faibles pertes de rendement de comptage. En ne comptant que dans cette gamma d'energies peu etendue, l'activite due a la presence de reactifs et d'autres agents de contamination emetteurs alpha residuels dans l'urine, qui n'est pas entierement decontaminee, se trouve egalement reduite de moitie et atteint un peu plus de 0,01 pc par echantillon preleve sur les urines recueillies pendant 24 h. La limite de detection a l'aide de cette methode est d'environ 0, 025 pc de {sup 239}Pu. (author) [Spanish] La memoria describe un metodo para determinaciones corrientes de plutonio en la orina. Tambien resume las investigaciones que llevaron a establecer este procedimiento y en las que se compararon diversas tecnicas de concentracion, purificacion y deposito electrolitico del plutonio. Con arreglo al procedimiento adoptado en definitiva, la orina se calcina en humedo y el residuo se disuelve con acido clorhidrico. El plutonio (IV) presente en la solucion asi obtenida se coprecipita con cupferrato de hierro y se extrae con cloroformo. Una vez evaporado este,, se oxida el residuo, se disuelve en acido clorhidrico y el hierro se extrae con eter diisopropflico. Seguidamente se evapora a sequedad la fase acuosa que contiene, al plutonio y se disuelve en una solucion acida de sulfato amonico desde la cual se separa el plutonio por deposito electrolitico sobre acero inoxidable. El rendimiento de esta ultima etapa es cuantitativo, siendo de 84 {+-} 7% para el proceso en conjunto. . El plutonio electrodepositado se recuenta con un detector de estado solido (diode de union de silicio) en un contador especialmente construido para este fin. La baja actividad de fondo inherente de este tipo de contadores puede disminuirse aun mas contando solamente las particulas alfa de energia comprendida entre 4.2 y 5,4 MeV. El buen poder de resolucion que se obtiene con capas delgadas de plutonio electrodepositado permite emplear un canal tan estrecho sin que la eficacia de recuento disminuya apreciablemente. Al efectuar el recuento en este intervalo restringido, la actividad de fondo debida a los reactivos y a la eliminacion incompleta de las impurezas de emisores alfa de la orina queda reducida tambien a la mitad, esto es, a un valor del orden de 0,01 pcuries por muestra de 24 horas. El limite de deteccion mediante este metodo es aproximadamente de 0,025 pc de {sup 239}Pu. (author) [Russian] Opisan metod prakticheskogo'opredelenija al'fa-izluchenija plutonija v moche. Pri razrabotke jetogo metoda sravnivalis' razlichnye metody koncentrirovanija, ochistki i jelektroliticheskogo osazhdenija plutonija ; podvoditsja itog jetih issledovanij. Soglasno prinjatomu v konechnom itoge metodu mochu podvergajut vlazhnomu ozoleniju, osadok rastvorjajut v soljanoj kislote. Plutonij (IV) podvergajut sovmestnomu osazhdeniju s kupferronatom zheleza iz jetogo rastvora i jekstragirujut hloroformom. Posle vyparivanija hloroformom osadok okisljajut, rastvorjajut v soljanoj kislote i jekstragirujut zhelezo di- izopropilovym jefirom. Vodnuju fazu, soderzhashhuju plutonij, vyparivajut i rastvorjajut v kislom sul'fate ammonija, iz kotorogo plutonij osazhdajut jelektroliticheski na nerzhavejushhej stali. Kolichestvennye vosstanovlenija na stadii jelektroliticheskogo osazhdenija dali 84 {+-} 7% Osazhdennyj plutonij podschityvali s pomoshh'ju diodnogo (tverdogo s kremnevym soedineniem) schetchika,sozdannogo dlja jetoj celi. Nizkij estestvennyj fon schetchika jetogo tipa byl jeffektivno snizhen putem podscheta lish' teh al'fa-chastic, kotor''ge imejut jenergiju 4.2 - 5,4 Mjev. Horoshee razreshenie, poluchaemoe s pomoshh'ju tonkogo jelektroosazhdennogo istochnika plutonija3obespechivaet vozmozhnost' ochen' malyh poter' jeffektivnosti scheta v jetom uzkom kanale. Pri schete vne'jetoj ogranichennoj oblasti jenergii kontrol'naja aktivnost', sozdavaemaja reaktivami i nepolnoj ochistkoj ot drugih al'fa-izluchatelej v moche, takzhe snizhaetsja na faktor porjadka 2, nemnogo vyshe 0,01 mkmkkjuri v-techenie 24 chasov. Predel obnaruzhenija s pomoshh'ju jetogo metoda sostavljaet okolo 0,025 mkmkkjuri plutonija-239. (author)

  3. A Low-Background Liquid-Scintlllation Counter for the Assay of Low-Specific Activity Tritiated Water; Compteur a scintillations a liquides, a faible mouvement propre, pour le dosage d'eau tritiee en faible activite specifique; ZHidkostnyj stsintillyatsionnyi schetchik s nizkim fonom dlya analiza nasyshchennoj tritiem vody s nizkoj udel'noj aktivnost'yu; Contador de centelleador liquido de reducida actividad de fondo para el analisis de agua pritiada de baja actividad especifica

    Energy Technology Data Exchange (ETDEWEB)

    Boyce, I S; Cameron, J F [Wantage Research Laboratory, Wantage (United Kingdom)

    1962-01-15

    In liquid-scintillation counting of tritiated water single photomultiplier counters and coincidence systems offer comparable sensitivities. To investigate low level counting a coincidence system was selected to avoid Uncertainties in the background due to single photon events arising from phosphorescence and chemiluminescenc e in the solution. With this system the background was found to be due largely to light originating in the photomultiplier photocathode. Using two photomultipliers with ''Pyrex'' photocathodes in contact in an 8 in thick iron shield experiments were conducted to determine the relative importance of the following possible courses of background : (a) Ionization and excitation of residual gas and of the semi-conductor dynode surfaces, particularly in regions where the current density is greatest. (b) Sparking, electroluminescence and field emission. (c) Positive ion feedback to the photocathode causing secondary electron emission. (d) Operation of the photocathode window itself as a phosphor for cosmic radiation, K{sup 40} beta particles or radiation from uranium daughter products. In particular it was found that contribution (c) was significantly lower than was previously supposed. Methods of minimizing these effects, including the use of quartz photocathodes, and special photomultipliers were investigated. In the finished design of counter the minimum detectable specific activity with a counting time of 30 min. is 6x10{sup 7} {mu}c/ml. (author) [French] Dans le dosage de l'eau tritiee au moyen d'un compteur a scintillations a liquides, les compteurs a photomultiplicateur unique et les ensembles a coincidences presentent une sensibilite du meme ordre. Pour faire des recherches sur la mesure des faibles activites, les auteurs ont choisi un dispositif monte en coincidence, afin d'eviter les incertitudes dans le mouvement propre causees par l'apparation de photons isoles, dus a la phosphorescence et a la chimioluminescenc e de la solution. Dans ce dispositif, on a constate que le mouvement propre provient surtout de la lumiere qui emane de la photocathode du photomultiplicateur. En utilisant deux photomultiplicateurs a photocathode en pyrex, en contact dans une protection en fer de 20 cm, on a procede a des experiences pour determiner l'importance relative des phenomenes ci-apres pouvant constituer le mouvement propre: a) Ionisation et excitation des gaz residuels et des surfaces des dynodes a semi-conducteurs, notamment aux endroits ou la densite du courant est la plus elevee; b) Production d'etincelles, electroluminescence et emission du champ; c) Retroaction positive des ions vers la photocathode, provoquant une emission d'electrons secondaire; d) Fenetre de la photocathode jouant elle-meme le role de scintillateur pour les rayons cosmiques, les particules beta du {sup 40}K et les rayonnements emis par les produits de filiation de l'uranium. Les auteurs ont notamment etabli que le facteur c) avait sensiblement moins d'importance qu'on ne l'avait suppose precedemment. Ils ont fait des recherches sur les methodes permettant de reduire ces effets au minimum, notamment en utilisant des photocathodes en quartz et des photomultiplicateurs speciaux. Avec l'ensemble de comptage concu par les auteurs, l'activite specifique minimum decelable est de 6x10{sup 7} {mu}c/ml, le temps de comptage etant de 30 minutes. (author) [Spanish] Cuando se trata de efectuar el recuento de agua tritiada dor centelleo de liquidos, los contadores de fotomultiplicador unico y los dispositivos de coincidencias presentan sensibilidades comparables. Con el fin de efectuar estudios sobre la medicion fe bajas actividades, los autores eligieron un sistema de coincidencias para evitar la incertidumbre en lo que respecta a la actividad de fondo debida a fotones aislados emitidos en virtud de la fosforescencia y quimioluminiscenci a de la solucion. Los autores comprobaron que, en este sistema, la actividad de fondo proviene principalmente de la luz que emana del fotocatodo del fotomultiplicador. Utilizando dos fotomultiplicadores con fotocatodos de pyrex en contacto, encerrados en un blindaje de hierro de 20 cm de espesor, hicieron experimentos para determinar la importancia relativa de las siguientes posibles causas de la actividad de fondo: a) Ionizacion y excitacion del gas residual y de las superficies del dinodo semiconductor, especialmente en las regiones en que la densidad de corriente es maxima; b) Formacion de chispas, electroluminiscencia y emision de campo; c) Realimentacion de iones positivos al fotocatodo, que provoca una emision de electrones, secundarios ; d) Funcionamiento de la propia ventana fotocatodica en caracter de ''fosforo'' para la radiacion cosmica, las particulas del {sup 40}K o las radiaciones de los productos de filiacion del uranio. Los autores comprobaron que, en particular, el factor c) interviene en una proporcion mucho menor que lo que se habia supuesto. Estudiaron metodos para reducir a un minimo estos efectos, incluyendo el uso de fotocatodos de cuarzo y fotomultiplicadores especiales. Con el dispositivo disenado por los autores, la minima actividad especifica detectable, con un tiempo de recuento de 30 min, asciende a 6 x 10{sup 7}{mu}c/ml. (author) [Russian] Pri schege zhidkostnykh stsintillyatsij nasytsennoj tritiem vody schetchiki s odnim fotoumnozhitelem i sistemy sovpadenij dayut pokazaniya sravnitel'noj chuvstvitel'nosti. Dlya issledovaniya scheta izlucheniya maloj intensivnosti byla primenena sistema sovpadenij dlya togo, chtoby izbezhat' neopredelennosti v fone, vyzyvaemom izmeneniemi odnogo fotona v rezul'tate fosforestsentsii i khimicheskoj lyuminestsentsii v rastvore. Bylo obnaruzheno, chto vozniknovenie fona v ehtoj sisteme ob{sup y}asnyaetsya glavnym obrazom dejstviem sveta, iskhodyashchego iz fotokatoda fotoumnozhitelya. Byli provedeny ksperimenty s primeneniem dvukh fotoumnozhitelej s fotokatodami Pireks v kontakte s zheleznym ehkranom tolshchinoj v 8 dyujmov dlv opredeleniya otnositel'noj vazhnosti sleduyushchikh vozmozhnykh faktorov fona: a) Ionizatsiya i vozbuzhdenie ostatochnogo gaza i poverkhnostej poluprovodnikovogo dinoda, osobenno v tekh zonakh, gde imeetsya samaya bol'shaya plotnost' potoka; b) Iskroobrazovanie , ehlektrolyuminestsentsiya i avtozlektronnaya ehmissiya; c) Obratnaya svyaz' polozhitel'nykh ionov s fotokatodom, chto vyzyvaet vtorichnuyu ehlektronnuyu emissiyu; d) Samostoyatel'noe dejstvie fotokatodnogo okna podobno lyuminoforu kosmicheskoj radiatsii, beta-chastitsam K{sup 40} ili radiatsii dochernikh produktov urana. V chastnosti, bylo obnaruzheno znachitel'no men'shee vozdejstvie faktora, chem ranee predpolagalos'. Byli issledovany metody umen'sheniya ehtikh vozdejstvij, vklyuchaya ispol'zovanie kvartsevykh fotokatodov i spetsial'nykh fotoumnozhitelej. V okonchatel'noj konstruktsii schetchika miiimal'nayaobiaruzhim aya udel'naya aktivnost' so vremenem scheta v 30 minut sostavlyaet 6 x 10{sup 7} mikrokyuri na milillitr. (author)

  4. Carbon-14 and Hydrogen-3 Measurement by Means of a Liquid Scintillation Spectrometer: Colour Quenching; Mesure du Carbone-14 et du Tritium a l'Aide d'un Spectrometre a Scintillateurliquide: Extinction Chromatique; Izmerenie soderzhaniya Ugleroda-14 i Vodoroda-3 s pomoshch'yu zhidkostnogo stsintillyatsionnogo spektrometra. oslablenie tsveta; Influencia de la Extincion Cromatica en la Medicion del Carbono-14 y del Hidrogeno-3 por Espectrometria del Centelleo Liquido

    Energy Technology Data Exchange (ETDEWEB)

    Iwakura, T.; Kasida, Y. [National Institute of Radiological Sciences, Chiba (Japan)

    1965-10-15

    An attempt was made to correlate colour quenching and wavelength of the absorption maximum in liquid scintillators. Attempts were also made to find a difference in discriminator ratio versus counting efficiency curves between chemical and colour quenching. Fourteen photosensitive cyanine dyes were used as colouring agents in alcohol solution. The concentration of the dye in the counting samples ranged from 0.5 to 10 x 10{sup -6} M to give the desired absorbance in the liquid scintillator medium. Toluene-1-{sup 14}C and toluene-{sup 3}H were used as the internal standards. Counting was carried out with a Packard TRI-CARB Model 314 EX2 liquid scintillation spectrometer. Discriminator settings were 100-1000 divisions for the red channel and 186-1000 divisions fox the green channel. The high voltage applied to the photomultiplier was selected to give balance point operation in the red channel in an unquenched sample. Concentration of dyes against extent of quenching was examined. Because of the characteristic wavelengths of light emitted by the scintillator systems and the response of the photomultipliers (S-11 response), it was expected that red and yellow solutions which have maximum absorption at 400-500 nm would show the greatest quenching effect. To evaluate the total colour quenching, the following relationship was used to define the total absorption coefficient: A = ({Sigma}A{sub i}W{sub i})/({Sigma}W{sub i}) where W{sub i} is the relative photomultiplier sensitivity for light within the spectral range i nm, and A{sub i} is the absorbance of light within the spectral range i nm used. Total absorbance was calculated for each 40 nm range. 360-400, 400-440 etc., to 520-560 nm. The reciprocal absorbance 1/A versus the counting efficiency shows a linear relationship over a wide range of counting efficiencies. The curves of the discriminator ratio versus counting efficiency show that when colour quenching becomes strong, the colour quenching curve separates from the chemical quenching curve in {sup 14}Ccounting. On the other hand, similar measurements made in counting {sup 3}H do not show a separation of the two quenching curves. (author). (author) [French] On s'est efforce de trouver une correlation entre l'extinction chromatique et la longueur d'onde d'absorption maximale des scintillateurs liquides. On a egalement cherche a trouver une difference entre les courbes exprimant l'efficacite du comptage en fonction du rapport du discriminateur, selon qu'il s'agit d'extinction chimique ou d'extinction chromatique. On a utilise comme colorants 14 cyanines photosensibles en solution alcoolique. On a fait varier la concentration de teinture dans les echantillons de comptage de 0,5 a 10x10{sup -6} M, de maniere a obtenir le pouvoir absorbant voulu dans le scintillateur liquide. Du toluene-1- 14C et du toluene-3 H ont servi d'etalons internes. On a procede au comptage avec un spectrometre a scintillateur liquide Packard TRI-CARB, modele 314 EX2. Les reglages du discriminateur etaient les suivants: 100 a 1000 divisions pour le canal rouge et 186 a 1000 divisions pour le canal vert. La haute tension appliquee au photomultiplicateur a ete choisie de maniere a obtenir le point d'equilibre dans le canal rouge pour un echantillon non eteint. On a etudie les concentrations des teintures en fcuction du degre d'extinction. En raison des longueurs d'onde caracteristiques de la lumiere emise par le scintillateur et de la reponse des photomultiplicateurs (reponse S-ll), on s'attendait que les solutions rou,geb et jaunes qui accusent une absorption maximale a 400-500 nm donnent l'effet d'extinction le plus prononce. En vue de calculer l'extinction chromatique totale, on a utilise la formule suivante pour determiner le coefficient d'absorption totale: A = ({Sigma}A{sub i}W{sub i})/({Sigma}W{sub i}), dans laquelle W{sub i} est la sensibilite relative du photomultiplicateur pour une lumiere emise sur une longueur d'onde de i nm et A{sub i} est le coefficient d'absorption de la lumiere emise sur la longueur dlonde de i nm dans la bande spectrale utilisee. On a calcule le coefficient d'absorption totale pour chaque bande de 40 nm soit 360-400, 400-440, etc. jusqu'a 520-560 nm. Le graphique de l'inverse du coefficient d'absorption 1/A en fonction de l'efficacite du comptage revele une relation lineaire pour un large intervalle d'efficacite de comptage. Les courbes donnant le rapport du discriminateur en fonction de l'efficacite de comptage montrent que, lorsque l'extinction chromatique devient forte, la courbe qui la represente se separe de la courbe d'extinction chimique dans le comptage de {sup 14}C. Au contraire, des mesures analogues faites avec {sup 3}H ne font pas apparaitre cette separation entre les courbes d'extinction. (author) [Spanish] Los autores procuraron establecer una relacion entre la extincion cromatica y la longitud de onda en el maximo de. absorcion de centelleadores liquidos. Asimismo intentaron hallar una diferencia en la razon de discriminacion en funcion de las curvas del rendimiento de recuento entre la extincion qufmica y la cromatica. Utilizaron 14 colorantes fotosensibles a base de cianina en solucion alcoholica. La concentracion del colorante en las muestras que se querfan analizar estaba comprendida entre 0,5 y 10 x 10{sup -6} M fin-de obtener la absorcion deseada en el centelleador liquido. Como patrones internos emplearon tolueno-1- {sup 14}C y tolueno-{sup 3}H. El recuento se efectuo con un espectrometro de centelleo liquido Packard TRI-CARB, modelo 314 EX2. El discriminador se graduo en 100 a 1000 divisiones para el canal rojo y en 186 a 1000 divisiones para el canal verde. El valor de la alta tension aplicada al fotomultiplicador se eligio con miras a conseguir un funcionamiento en el punto de equilibrio del canal rojo para una muestra sin extintor. Los autores estudiaron la concentracion de colorantes en funcion del grado de extincion. Debido a la longitud de onda caracteristica de la luz emitida por los centelleadores y la respuesta del fotomultiplicador (S-ll), se supuso que la solucion roja y amarilla, que tiene un poder maximo de absorcion a 400-500 nm, ejerceria el efecto de extincion mas acusado. Para evaluar la extincion cromatica total el coeficiente de absorcion total se definio mediante la expresion A = ({Sigma}A{sub i}W{sub i})/({Sigma}W{sub i}), donde W{sub i} es la sensibilidad relativa del fotomultiplicador a luz de una longitud de onda i nm y A{sub i} es la absorbencia de luz de longitud de onda i nm en el intervalo espectral empleado. La absorbencia total se calculo para una serie de intervalos de 40 nm (360 a 400 , 400 a 440, etc., hasta 520 a 560 nm). La inversa de la absorbencia (1/A) es proporcional al rendimiento de recuento de un amplio intervalo de valores de este. En el recuento del {sup 14}C, las curvas de la razon de discriminacion en funcion del rendimiento de recuento ponen de manifiesto que a medida que se intensifica la extincion cromatica, la curva correspondiente se separa de la curva de extincion qufmica. Por otra parte, mediciones similares efectuadas durante el recuento de {sup 3}H no revelan separacion de las dos curvas de extincion. (author) [Russian] Byla sdelana popytka ustanovit' sootnoshenie mezhdu oslableniem cveta i dlinoj volny maksimuma pogloshhenija v zhidkostnyh scintilljatorah. Byla takzhe sdelana popytka opredelit' razlichija krivyh zavisimosti kojefficienta diskriminatora ot jeffektivnosti scheta dlja himicheskogo oslablenija i oslablenija cveta. Chetyrnadcat' fotochuvstvitel'nyh cianinovyh krasok bylo ispol'zovano v kachestve krasjashhih agentov v rastvore spirta. Koncentracija kraski v izmerjaemyh obrazcah menjalas' ot 0,5 do 10-10{sup 6} molja, chtoby poluchit' trebujushheesja pogloshhenie v zhidkoj scintilljacionnoj srede. V kachestve vnutrennih standartov ispol'zovalis' toluol-1-uglerod-14 i toluol- vodorod-3. Schet proizvodili s pomoshh'ju zhidkostnogo scintilljacionnogo spektrometra Pakard TRI-CARB, model' 314 EH2. Nastrojka diskriminatora sostavljala 100-1000 delenij dlja krasnogo kanala i 186-1000 delenij dlja zelenogo. Vysokoe naprjazhenie, primenjaemoe dlja fotoumnozhitelja, vybrali dlja togo, chtoby obespechit' uravnoveshennuju tochechnuju rabotu v krasnom kanale pri neoslablennom obrazce. Koncentracija krasok byla izuchena po stepeni oslablenija. Vsledstvie harakternosti dliny voln sveta, ishodjashhego iz scintilljatornyh sistem i reakcii fotoumnozhitelej (reakcija S-I), predpolagalos', chto krasno-zheltyj rastvor, kotoryj imeet maksimum pogloshhenija pri 400 - 500 mmk budet imet' samyj bol'shoj jeffekt oslablenija. Chtoby ocenit' obshhee oslablenie cveta dlja opredelenija kojefficienta obshhego pogloshhenija ispol'zovalos' sledujushhee otnoshenie: A = ({Sigma}A{sub i}W{sub i})/({Sigma}W{sub i}), gde W{sub i} - otnositel'naja chuvstvitel'nost' fotoumnozhitelja k svetu s dlinoj volny i mmk; a A{sub i} - pogloshhenie sveta s dlinoj volny i mmk v predelah ispol'zuemogo spektra. Obshhee pogloshhenie bylo rasschitano dlja kazhdogo intervala v 40 mmk, naprimer dlja 360 - 400, 400 - 440 i t.d. do 520 - 560 mmk. Jekvivalentnoe pogloshhenie 1/A v zavisimosti ot jeffektivnosti scheta pokazyvaet linejnuju zavisimost' v shirokom diapazone jeffektivnosti scheta. Krivye zavisimosti kojefficienta diskriminatora ot jeffektivnosti scheta pokazyvajut, chto, kogda oslablenie cveta stanovitsja sil'nym, krivaja oslablenija cveta otdeljaetsja ot krivoj himicheskogo oslablenija pri schete ugleroda-14. S drugoj storony, proizvedennye pri schete vodoroda-3 analogichnye izmerenija ne pokazyvajut razdelenija dvuh krivyh oslablenija. (author)

  5. FY 2000 report on the basic survey to promote Joint Implementation, etc. Feasibility study of the effective utilization of by-product high-sulfur concentration petroleum coke at Fujian Petrochemical Co. Ltd., Fujian Province, China; 2000 nendo kyodo jisshi nado suishin kiso chosa hokokusho. Chugoku sekiyu kako shudan koji fukusei ren'yu kako yugen koji Fujian koio nodo sekiyu cokes no yuko riyo ni kansuru F/S chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of conserving energy and reducing greenhouse effect gas emission, an investigational study was conducted for the project on the effective utilization of high-sulfur petroleum coke at Fujian Petrochemical Co., Fujian Province, China. In the project, IGCC (integrated gasification combined cycle) power generation facilities are introduced to the refinery of Fujian Petrochemical Co. By gasifying the residues produced from the refinery as raw material, the gas clean the same as natural gas is produced and is used as power generation use fuel. As a result of the study, the energy conservation amount was 94,300 toe/y, and was 1,414,500 toe in cumulative amount during 15 years. Further, the amount of greenhouse effect gas reduction was 291,600 t-CO2/y, and was 4,374,000 t-CO2 in cumulative amount during 15 years. The construction cost of the project is approximately 29.7 billion yen. The annual profit to be obtained from the project is approximately 8.66 billion yen, which is indicated by difference between before and after the implementation of the project. The calculated years required for return of investment were 3.4. (NEDO)

  6. Fiscal 2000 project of inviting proposals for international joint research - invitation for international proposal (Power generation No.14). Achievement report on joint research for utilizing Russia's now-unused high-viscosity crude oil as fuel for power generation; 2000 nendo kokusai kyodo kenkyu teian kobo jigyo - kokusai teian kobo (hatsuden No.14). Russia miriyo konensei gen'yu no denryoku nenryo riyo kyodo kenkyu chosa seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The Russkoye high-viscosity oil field is located in the western part of Siberia, Russia. Joint research is under way to develop a technology for reducing the viscosity for the collection of crude oil through the utilization of a gas condensate discharged by a neighboring gas field. This report comprises eight chapters, namely, (1) the background, purpose, and contents of the research, (2) Russia's oil resources and oil industry, (3) high-viscosity oil fields in Russia, (4) analysis of Russkoye crude oil and gas condensates yielded in Russia, (5) methods for viscosity reduction, (6) evaluation of combustibility, (7) scenario for developing the Russkoye oil field, and (8) research results as summarized and future tasks. Studied in chapter (5) are approaches to viscosity reduction, methods for emulsification, and a method for viscosity reduction by use of a gas condensate. These are tested and the results after analysis clearly show that the Russkoye crude oil, when blended with a gas condensate, will turn transportable and will provide a fuel equivalent to fuel oil C. (NEDO)

  7. Fiscal 2000 project of inviting proposals for international joint research - invitation for international proposal (Power generation No.2). Achievement report on development of high-efficiency low-temperature power generation device using SOFC containing yttria-doped ceria layer; 2000 nendo kokusai kyodo kenkyu teian kobo jigyo - kokusai teian kobo (hatsuden No.2). Yttria gan'yu ceria so wo yusuru SOFC kokoritsu teion sadogata hatsuden sochi no kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Efforts continue to develop a solid oxide fuel cell (SOFC) capable of consuming methane, propane, and the like, as fuel directly and of operation at 650 degrees C or lower. The efforts in concrete terms involve the development of an anode material, an electrolyte, and a cathode material not to suffer carbon precipitation and the evaluation of power generation performance of a hydrocarbon fueled single cell. Activities are conducted in the five domains of (1) the fabrication of an SOFC single cell and a preliminary study, (2) evaluation of solid electrolyte thermal stability using X-ray diffraction, (3) anodic carbon precipitation test and single cell performance test, (4) survey of technical trends overseas, and (5) the goal and self-management. In domain (1), technologies are developed to form thin film anodes of Ni-GDC (gadolinium-doped ceria), Cu-GDC, Ni-YSZ (yttria-stabilized zirconia), and the like, for which the ultrasonic spray method and slurry coat method are used. In the study of cell manufacturing, the anode support method and cathode support method are investigated. The anode support method is used to fabricate a thin film, a thin YSZ film is successfully fabricated for typical Ni-YSZ. (NEDO)

  8. A Quick Method of Measuring and Analyzing {beta} Emitters in Solution of Very Low-Level Specific Activity; Remarques sur une technique rapide de mesure et d'analyse d'emetteurs {beta} en solution de tres faible activite specifique; Zamechaniya o bystroj tekhnike izmereniya i analize izluchatelej {beta}-chastits v rastvore s ochen' slaboj spetsificheskoj aktivnost'yu; Observaciones sobre un metodo rapido de medicion y analisis de emisores {beta} en soluciones de muy baja actividad especifica

    Energy Technology Data Exchange (ETDEWEB)

    Le Gallic, Y; Grinberg, B; Thenard, M [Centre d' Etudes Nucleaires de Saclay (France)

    1960-06-15

    1. Description of a measuring instrument with a low-level background, for measuring radioactive materials in liquid form. Essentially the instrument consists of two flat counters, each with one hole, and one flat counter with two holes, mounted parallel to each other and enclosed in a casing of counters mounted in anti-coincidence with the inner counter. 2. Possible applications of the method: a) To measure much lower-level specific activities than with liquid counters, and particularly soft {beta} emitters; b) To detect radioactive impurities within a radionuclide (e. g. 2/10,000 of P{sup 32} in S{sup 35}); c) For most radionuclides, to measure, without previous concentration, specific activities corresponding to the tolerance limits permitted at present. (author) [French] 1. Description d'un dispositif de mesure a faible mouvement propre, destine a la mesure de produits radioactifs sous forme liquide, et qui comprend essentiellement 2 compteurs plats a une fenetre, et un compteur plat a deux fenetres, disposes parallelement et enfermes a l'interieur d'une gaine de comp- teurs montes en anticoincidence avec les premiers. 2. Possibilites et domaines d'utilisation de la methode: a) permet de mesurer des activites specifiques beaucoup plus faibles qu'avec les compteurs a liquides, particulieremen t avec les emetteurs {beta} mous; b) permet de deceler des impuretes radioactives au sein d'un radioelement (ex. 2/10.000 de P{sup 32} dans S{sup 35}); c) permet, pour la plupart des radioelements, de mesurer, sans concentration prealable, des activites specifiques egales respectivement aux limites de tolerance aujourd'hui admises. (author) [Spanish] 1. Los autores describen un dispositivo de medicion poco sensible a la actividad de fondo, destinado a medir la radiactividad de sustancias liquidas. El dispositivo consta fundamentalment e de dos contadores planos provistos de una ventana y de un contador plano con dos ventanas, disquestos paralelamente en el interior de una vaina de contadores conectados en anticoincidencia con los primeros. 2. Ademas enumeran las posibilidades y campos de utilizacion del metodo que: a) especialmente en el caso de los emisores {beta} blandos, permite medir actividades especificas mucho mas bajas que cuando se utilizan contadores para liquidos; b) permite descubrir las sustancias radiactivas presentes como impurezas en determinados radioelementos (por ejemplo, 2/10 000 de P{sup 32} en S{sup 35}); c) para la mayor parte de los radioelementos permite medir, sin necesidad de proceder a una concentracion previa, actividades especificas de igual orden de magnitud que los limites de tolerancia actualmente admitidos. (author) [Russian] 1. Opisanie mekhanizma izmereniya so slabym fonom prednaznachennog o dlya izmereniya radioaktivnykh produktov v zhidkom sostoyanii, kotoryj sostoit v osnovnom iz dvukh ploskikh schetchikov s odnim oknom i odnogo ploskogo schetchika s dvumya oknami, raspolozhenny kh parallel'no drug k DRUGU i izolirovanny kh vnutri zashchitnoj obolochkoj schetchikov, vstavlen- nykh takim obrazom, chtoby oni ne sovpadali s pervymi. 2. Vozmozhnosti i oblasti ispol'zovaniya metoda: a) ehtot metod pozvolyaet izmerit' gorazdo bolee slabuyu spetsificheskuyu aktivnost', chem ehto vozmozhno s zhidkotnymi schetchikami, v chastnosti s izluchatelyami ne zhestkikh {beta}-chastits; b) ehtot metod pozvolyaet obnaruzhivat' radioaktivnye primesi vnutri radioehlementa (napr. 2/10 OOO R{sup 32} v S{sup 35}); s) ehtot metod pozvolyaet dlya bol'shinstva radioehlemento v izmeryat' bez predvaritel'no j kontsentratsii spetsificheskuyu aktivnost' sootvetstvenno ravnuyu prinyatym v nastoyashchee v nastoyashchee vremya predel'nym dopuskam. (author)

  9. FY 1999 Report on results of development of high-efficiency energy system technologies for transportation and domestic use. R and D of polymer electrolyte fuel cells, power system technologies, and several kW class domestic power systems operating at normal pressure; 1999 nendo un'yu minseiyo kokoritsu energy system gijutsu kaihatsu, kotai kobunshigata nenryo denchi no kenkyu kaihatsu, hatsuden system gijutsu kaihatsu, joatsu sadogata su kW kyu kateiyo dengen system no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Described herein are the FY 1999 results of the research and development project aimed at development of fuel cell systems for power source systems suitable for domestic use. The programs for development of fuel cell body include improvement of the anode forming method for increasing its CO tolerance, enhancing cell performance at 0.5mg-metal/cm{sup 2} as the catalyst quantity to a level almost comparable to that obtainable at 0.9mg-metal/cm{sup 2}. The programs for development of the fuel supply system include studies on endurance of the elements, e.g., starting-up/shutting-down of the Ru/Al{sub 2}O{sub 3} catalyst, using a microreactor, confirming that it is serviceable for at least 1,000 hours. The natural gas reformer is developed and operated, on a trial basis, achieving stable supply of steam and fuel, and thermal efficiency of 82.7%. The operation researches include development and operation of a 1kW class module, achieving the performance surpassing the FY 1999 targets (average cell voltage: 0.70V, output: 1.27kW) with a simulated reformate gas at an air utilization rate of 20% and current density of 0.3A/cm{sup 2}. (NEDO)

  10. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yu-Song Guo Zhong-Duo Wang Cheng-Zhong Yan Yu-Lan Zhang Jin-Nan Zheng Yuan-Min Xu Tao Du Chu-Wu Liu · More Details Fulltext PDF ... Aifu Yang Dapeng Sun Shikai Liu Ying Dong Zhong Chen Zunchun Zhou · More Details Fulltext ...

  11. Characterization and photocatalytic activity of boron-doped TiO2 thin ...

    Indian Academy of Sciences (India)

    Wintec

    Chen Daimai, Wang Dong Yang and Jiang Zhongyi 2006 Ind. Eng. Chem. 45 4110. Cheng Jen-hao 2003 A study on photocatalytic oxidation of aque- ous chlorobenzene solution by nanostructured film of TiO2,. Master Thesis, National Sun Yat-Sen University, Taiwan. Deki S, Henin Yu Yu Ko, Fujita T, Akamatsu K, Mizuhata ...

  12. Fluorescence of Er3+:AlN Polycrystalline Ceramic

    Science.gov (United States)

    2012-01-01

    Refractive Index of Air,” Metrologia 2(2), 71–80 (1966). 31. V. Yu. Davydov, Yu. E. Kitaev, I. N. Goncharuk, A. N. Smirnov, J. Graul, O. Semchinova, D...sieve and stored in a vacuum desiccator. The size distribution of the powders was measured using a Horiba LA -910 Light Scattering Particle Size

  13. Download this PDF file

    African Journals Online (AJOL)

    pc

    2017-11-10

    Nov 10, 2017 ... ts of alkyl chain length on particles morphology were primarily studied ..... [3] Li Z, Yu L, Zheng L, Li N, Han S, Li G. Characterization studies on the ionic ... [4] Chiang YD, Lian HY, Leo SY, Wang SG, Yamauchi Y, Wu KC. ... [20] Yu YJ, Xing JL, Pang JL, Jiang SH, Lam KF, Yang TQ, Xue QS, Zhang K, Wu P.

  14. DNA pattern recognition using canonical correlation algorithm

    Indian Academy of Sciences (India)

    2015-09-28

    Sep 28, 2015 ... were considered as the two views, and statistically significant relationships were established between these two ... Canonical correlation analysis is to find two sets of basis ..... Jing XY, Li S, Lan C, Zhang D, Yang JY and Liu Q 2011 Color ... Yu S, Yu K, Tresp V and Kriegel HP 2006 Multi-output regularized.

  15. Brain-Based Devices for Neuromorphic Computer Systems

    Science.gov (United States)

    2013-07-01

    Science. 233(4771):1416-9. Goldman-Rakic, P.S. (1995). Cellular basis of working memory. Neuron. 14(3):477-85. Haider, B., Krause, M.R., Duque , A., Yu...Haider, B., Krause, M. R., Duque , A., Yu, Y., Touryan, J., Mazer, J. A., and McCormick, D. A. (2010). Synaptic and network mechanisms of sparse and

  16. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. YU-HUI HOU. Articles written in Journal of Chemical Sciences. Volume 130 Issue 1 January 2018 pp 6. Efficient click reaction towards novel sulfonamide hybrids by molecular hybridization strategy as antiproliferative agents · DONG-JUN FU YU-HUI HOU SAI-YANG ZHANG ...

  17. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Journals; Journal of Genetics; Volume 95; Issue 1. Novel NPHS1 gene mutations in a Chinese family with congenital nephrotic syndrome. Fengjie Yang Yaxian Chen Yu Zhang Liru Qiu Yu Chen Jianhua Zhou. Research Note Volume 95 Issue 1 March 2016 pp 161- ...

  18. Exact solitary ion acoustic waves in a magnetoplasma

    International Nuclear Information System (INIS)

    Ray, D.

    1979-01-01

    Solitary ion acoustic waves in a magnetoplasma have been studied by Shukla and Yu [J. Math. Phys. 19, 2506 (1978)]. A more rigorous study confirms the conditions that Shukla and Yu said would be necessary for humps. However, it is shown that a density cavity is also possible in the limiting case

  19. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. R G Veliyev1 Mir Hasan Yu Seyidov1 2 E M Kerimova1 R Z Sadykhov1 Yu G Asadov1 F M Seyidov1 N Z Gasanov1. Institute of Physics, Azerbaijan National Academy of Sciences, Az 1143, Baku, Azerbaijan; Department of Physics, Gebze Institute of Technology, Gebze 41400, Kocaeli, Turkey ...

  20. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 122; Issue 6. Theoretical study of nucleophilic halogenalkylation of propylene oxide with halogenmethane and dihalogenmethane anion. Tao Liu Xiang-Chen Yin Guo-Dong Liu Zhang-Yu Yu. Full Papers Volume 122 Issue 6 November 2010 pp 901-909 ...

  1. Projects of Earth Sciences Supported by National Natural Science Foundation of China

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    -shou 40001019\tGenetic Algorithm Approach to Automation and Intelligence of Map Name Placement\tFAN Hong 40001020\tEnvironmental Magnetic Study of Sedimentary Iron Cycling during Early Diagnoses\tZHANG Wei-guo 40001021\tModeling of Nitrogen and Water Input-yield-leaching Loss Response and the Nitrogen Transformation and Transportation\tZHANG Guo-liang 40001022\tThe Study on the Regional Differentiation of Lake Environment Response to Southwest Monsoon Climate\tPENG Jin-lan 40001023\tCritical Loads of Acid Deposition for Ecosystems and Their Exceedance in Regions Suffered from Acid Deposition in China\tTAO Fu-lu 40031010\tRegional Environmental Processes of Typical Trace Organic Pollutants\tTAO Shu 40061001\tAnalysis on the Structure of Karst Watershed and the Characteristics of Low Flow\tLIANG Hong 40061002\tThe Development Feature, Dynamic Mechanism and Coordination Research of Urban Concentric Region in West of Yunnan Province and Its Demonstration to Undeveloped, Minority Concentric Region of China\tWU Qi-yan 40061003\tThe REE Background Value and Its Influence on Soil Fertility in Laterite in the Hainan Island\tBI Hua 40061004\tStudies on the Mechanism of Soil Fertility Degradation and Techniques of Fertilization Under Arable Soils Condition in the "One-Jiang River and Two-He River" Region in Tibet\tCAI Xiao-bu 40061005\tA Study on Major Factors, Countermeasures and Mechanism of Bahia Grass Later-stage Degeneration at Rare-earth Tailings\tDONG Wen-da 40061006\tStudy on Soil Erosion and Land Use Security Pattern in Jinsha River Basin of Yunnan\tYANG Zi-sheng 40061007\tA Study on Environment Dynamic Chart of Southern Mountain Area of Ningxia under Eco-Restoration and Wide Development in West China\tSUI Yu-zhu 40061008\tThe Site Study of Environment Carrying Capacity for Tourism in Bita Reserve, Northwestern Yunnan\tYANG Gui-hua 40071001\tResearch on Sedimentary Processes and Varve Records of Lake Environment for Meromictic Lake on the Qinghai-Xizang (Tibet) Plateau\tLI Shi

  2. Evaluation of effectiveness in a novel wound healing ointment ...

    African Journals Online (AJOL)

    Evaluation of effectiveness in a novel wound healing ointment-crocodile oil burn ointment. Hua-Liang Li, Yi-Tao Deng, Zi-Ran Zhang, Qi-Rui Fu, Ya-Hui Zheng, Xing-Mei Cao, Jing Nie, Li-Wen Fu, Li-Ping Chen, You-Xiong Xiong, Dong-Yan Shen, Qing-Xi Chen ...

  3. QING LIN

    Indian Academy of Sciences (India)

    QING LIN. Articles written in Journal of Genetics. Volume 96 Issue 4 September 2017 pp 535-544 RESEARCH ARTICLE. Effects of genetic variants of the bovine WNT8A gene on nine important growth traits in beef cattle · YONG-ZHEN HUANG YONG ZOU QING LIN HUA HE LI ZHENG ZI-JING ZHANG YONG-LONG DANG ...

  4. Synthesis and structures of two new Cu(I) frameworks bearing1,3 ...

    Indian Academy of Sciences (India)

    DOI 10.1007/s12039-016-1100-6. Synthesis and structures of two new Cu(I) frameworks bearing1,3-bis(4-pyridyl)propane and inorganic linkers. ZHAOBO HUa, BO LIb,∗, WENQIANG JUa, YUNING LIANGa and ZILU CHENa,∗. aState Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources,.

  5. (BIO) promotes the proliferation of mouse male germline s

    African Journals Online (AJOL)

    AJB2

    2012-01-18

    Jan 18, 2012 ... and Jinlian Hua1*. 1College of Veterinary Medicine, Shaanxi Centre of Stem Cells Engineering and Technology, Key Lab for Animal ... regulator of many signaling pathways with the capacity to maintain the pluripotency of human and ..... is an integral component of the core regulatory circuitry of embryonic.

  6. mitigating mitigating free riding in peer-to-peer networks

    African Journals Online (AJOL)

    eobe

    The performance of peer-to-peer systems is based on the quality and quantity of resource contributions from peer systems ... riding [3]. There are several measurement studies ...... J. S. Hua, D. C. Huang, S M Yen, and C. W. Chena, “A dynamic.

  7. mamta balodi

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences. MAMTA BALODI. Articles written in Proceedings – Mathematical Sciences. Volume 126 Issue 3 August 2016 pp 341-352 Research Article. Diamond lemma for the group graded quasi-algebras · MAMTA BALODI HUA-LIN HUANG SHIV DATT KUMAR · More Details ...

  8. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... point property and the Jacobian of Y satisfies the diagonal property. We compute some cohomologies of Picard bundles on the compactified Jacobian and its desingularization. pp 341-352 Research Article. Diamond lemma for the group graded quasi-algebras · MAMTA BALODI HUA-LIN HUANG SHIV DATT KUMAR.

  9. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. PING-YING TANG1 GUO-HUA HUANG1 QING-LIAN XIE1 JIAN-YING LI1. Key Laboratory of New Electric Functional Materials of Guangxi Colleges and Universities, Guangxi Teachers Education University, Nanning 530023, China ...

  10. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    The approximate analytical bound-state solutions of the Schrödinger equation for the Wei Hua oscillator are carried out in N-dimensional space by taking Pekeris approximation scheme to the orbital centrifugal term. Solutions of the corresponding hyper-radial equation are obtained using the conventional Nikiforov–Uvarov ...

  11. Electron paramagnetic resonance parameters and local structure for ...

    Indian Academy of Sciences (India)

    HUA-MING ZHANG. 1. , GUANG-DUO LU. 1 ... the above ZFSs, the local structure information for the impurity Gd. 3+ is obtained, i.e., .... parameters, extended X-ray absorption fine-structure (EXAFS) measurements and crystal-field spectrum ...

  12. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Genetic variants of retinol-binding protein 4 in adolescents are associated with liver function and inflammatory markers but not with obesity and insulin resistance. Chin-Jung Lin Nain-Feng Chu Yi-Jen Hung Dee Pei Chien-Hsing Lee Fone-Ching Hsiao Chieh-Hua Lu Chang-Hsun Hsieh. Research Note Volume 94 Issue 3 ...

  13. Fulltext PDF

    Indian Academy of Sciences (India)

    YIMING LU1,3, PING HE2,∗, SHU-HUA MA3, GUO-ZHI LI4 and. SALEH MOBAYBEN1. 1Laboratory of Train Network, Department of Train Control Tech., Research Center of Product. & Tech., CRRC TANGSHAN CO., LTD, No. 3, Changqian Rd, Fengrun DIST, Tangshan,. Hebei, 063035, People's Republic of China. 2School ...

  14. Identification and Classification of Player Types in Massive Multiplayer Online Games Using Avatar Behavior

    Science.gov (United States)

    2011-08-01

    Kuan-Ta, Jhih-Wei Jiang, Polly Huang, Hao-Hua Chu, Chin-Laung Lei, and Wen-Chin Chen, “Identifying MMORPG Bots: A Traffic Analysis Approach”, EURASIP...in MMORPGs ”, Proceedings of DiGRA 2005 Conference: Changing Views – Worlds in Play Loeffelholz, Bernard, Earl Bednar, Kenneth W. Bauer, “Predicting

  15. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    CHEN AI-HUA1 MENG SU-CI2 ZHOU KAI1 WANG CONG-CONG1 ZHAO WEI2 WANG AI-JIAN2 QIAN JUN2. School of Chemistry & Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, People's Republic of China; School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang ...

  16. Acupuncture for serum uric acid in patients with asymptomatic hyperuricemia: A randomized, double-blind, placebo-controlled trial.

    Science.gov (United States)

    Huang, Yingjuan; Meng, Jun; Sun, Baoguo; Xiang, Ting; Zhou, Xin; Xu, Biyu; Wu, Yingzi; Chen, Zexiong; Zhang, Shijun

    2017-04-01

    Hyperuricemia (HUA) is the most common disease associated with cardiovascular disease, metabolic syndrome, hypertension, and kidney disease. The objective of the current study was to evaluate the preliminary efficacy, mechanism, and safety of acupuncture on serum uric acid in patients with asymptomatic HUA. A randomized, placebo-controlled trial among 123 patients with asymptomatic HUA was conducted. The acupoints used in the acupuncture group were bilateral Five Shu in Spleen Meridian. Each participant received the intervention once daily for 10 consecutive days. The sham group received the same treatment duration on the same acupoints by the Park Sham Device. All patients underwent measurements of serum or urine creatinine, uric acid, serum lipid profiles, fasting plasma glucose, HbA1c, xanthine oxidase (XOD) and urate-anion exchanger (URAT-1). At the end of the intervention, the individuals in the acupuncture group were found to have significantly less levels of serum uric acid than those in the sham group [(453±65 vs. 528±81) μmol/L, puric acid level, urine pH value and 24-hour urine volume than the sham treatment (puric acid in a Chinese HUA patient population. The mechanism might be associated with the decrease level of enzyme URAT-1. ChiCTR-TRC-13004122. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Guangdong Aluminum to Raise RMB 3 billion for New Production Base in Guizhou

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    <正>On July 7, a loan signing ceremony was held between the Guangdong Aluminum Group, China Construction Bank, Hua Xia Bank and Guangzhou Bank Consortium. It is reported that these banks will provide Guangdong Aluminum Group with RMB 30 billion for an alu-minum oxide and supporting bauxite mining project in Guizhou.

  18. 77 FR 66084 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2012-11-01

    ... BOUCHARD RAYMOND JOSEPH BOULLE II JEAN-RAYMOND BROMLEY MARGARET ANNE BROWNE CARLA EVELYN BRUCE JAMES TODD... CAMINOS MICHELE CLARE CAMPBELL JESSICA ANNE CHANG WAYNE WEN TIEN CHAN-PALAY VICTORIA LYE-HUA CHEN HOPE MI... RICHARD JOSEPH ARTHUR FUKUDA MEGUMI GAEHWILER YANNIK PETER GEIGER DANIEL CHRISTIAN GEIGER MICHAEL MATTHIAS...

  19. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. ZI-JING ZHANG. Articles written in Journal of Genetics. Volume 96 Issue 4 September 2017 pp 535-544 RESEARCH ARTICLE. Effects of genetic variants of the bovine WNT8A gene on nine important growth traits in beef cattle · YONG-ZHEN HUANG YONG ZOU QING LIN HUA HE LI ...

  20. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Li-Long Liu, Kai Xu, Lu-Mei Kang, Shu-Ping Jiang, Qing-Hua Wang, Lei Zhang, Shao-Gui Wan, Hong-Ping Chen, 113-121 ... Cytological effects of pulsed electromagnetic fields and static magnetic fields induced by a therapeutic device on in vivo exposed rats · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  1. Towards a Theory of Vernacularisation: Insights from Written Chinese Vernaculars

    Science.gov (United States)

    Snow, Don

    2013-01-01

    This paper examines the history of four Chinese vernaculars which have developed written forms, and argues that five of the patterns Hanan identifies in the early development of Bai Hua can also be found in the early development of written Wu, Cantonese, and Minnan. In each of the cases studied, there is a clear pattern of early use of the…

  2. Total phenol content of guava fruit and development of an in vitro regeneration protocol amenable to genetic improvement

    Science.gov (United States)

    Total soluble phenolics in two white (‘Allahabad Safeda’ and ‘Lucknow-49’), two pink (‘Beaumont’ and ‘Gushiken Sweet’), and three red fleshed (‘Ka Hua Kola’, ‘Ruby Supreme’ and ‘Red Fleshed’) guava (Psidium guajava. L.) fruits were assessed using the Folin-Ciocalteu procedure. ‘Allahabad Safeda’ and...

  3. Total Arterial Off‑pump Coronary Revascularization with a Bilateral ...

    African Journals Online (AJOL)

    Total Arterial Off‑pump Coronary Revascularization with a Bilateral Internal Mammary Artery Y Graft (208 cases). Jun-Feng Yang, Hong-Chao Zhang1, Cheng-Xiong Gu, Hua Wei. INTRODUCTION. AY graft is a graft formed by the left internal mammary artery (LIMA) connected to the left anterior descending (LAD) artery and ...

  4. Lnc-ing inflammation to disease

    CSIR Research Space (South Africa)

    Magagula, L

    2017-08-01

    Full Text Available by RNAi more than by antisense oligonucleotides. Nucleic Acids Res. 44, 863–877 doi:10.1093/nar/gkv1206 75 Zhen, S., Hua, L., Liu, Y.-H., Sun, X.-M., Jiang, M.-M., Chen, W. et al. (2017) Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated...

  5. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 93; Issue 1. Genomewide survey and characterization of metacaspase gene family in rice (Oryza sativa). Likai Wang Hua Zhang. Research Article Volume 93 Issue 1 April ... Keywords. metacaspases; OsMC gene family; expression profiles; domestication; rice; Oryza sativa.

  6. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. XIAOWEN ZHANG. Articles written in Bulletin of Materials Science. Volume 37 Issue 4 June 2014 pp 895-902. Structural evolution, electrical and optical properties of AZO films deposited by sputtering ultra-high density target · Jiwen Xu Zupei Yang Hua Wang Xiaowen Zhang.

  7. Study of Cu-doping effects on magnetic properties of Fe-doped ZnO ...

    Indian Academy of Sciences (India)

    Administrator

    To take into account the random distribution of ... and spin–orbit interaction were taken into account. .... Lee H J, Jeong S-Y, Ryong Cho C and Hong Park C 2002 Appl. Phys. Lett. ... Zhang Hua-Wei, Wei Zhi-Ren, Li Zhi-Qiang and Dong Guo-Yi.

  8. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Jianchang Du1 Xingna Wang1 2 Mingsheng Zhang1 Dacheng Tian1 Yong-Hua Yang1. State Key Laboratory of Pharmaceutical Biotechnology, Department of Biology, Nanjing University, Nanjing 210093, China; Center for Drug Discovery and Design, State Key Laboratory of Drug Research, Shanghai Institute of Materia ...

  9. Browse Title Index

    African Journals Online (AJOL)

    Items 201 - 250 of 2037 ... Vol 14, No 11 (2015), Antibacterial Activity and Mode of Action of Mentha arvensis Ethanol Extract against Multidrug-Resistant Acinetobacter baumannii, Abstract PDF. Ling Zhang, Shu-gen Xu, Wei Liang, Jun Mei, Yue-ying Di, Hui-hua Lan, Yan Yang, Wei-wei Wang, Yuan-yuan Luo, Hou-zhao Wang.

  10. Tropical Journal of Pharmaceutical Research - Vol 14, No 11 (2015)

    African Journals Online (AJOL)

    Antibacterial Activity and Mode of Action of Mentha arvensis Ethanol Extract against Multidrug-Resistant Acinetobacter baumannii · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Ling Zhang, Shu-gen Xu, Wei Liang, Jun Mei, Yue-ying Di, Hui-hua Lan, Yan Yang, ...

  11. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yan-Qin Xu Guo-Yan Wei Yin Zhou Fei Ge Guang-Ming Luo · More Details Fulltext PDF. pp e25-e28. Abundance and characteristics of microsatellite markers in Gansu zokor (Eospalax cansus), a fossorial rodent endemic to the Loess plateau, China · Junhu Su Limin Hua Jing Wang Dianne M. Gleeson Yanming Wei Robyn ...

  12. 'Zusanli' (ST.36) on the radiopharmaceutical biodistribution in Wistar ...

    Indian Academy of Sciences (India)

    ... Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, 20551-030, Rio de Janeiro, RJ, Brazil; Department of Electrical Engineering, National Tsing Hua University, Hsinchu 30013 Taiwan, Republic of China; Faculty of Medicine and Health Sciences, University of Tunku Abdul Rahman (UTAR), Kuala Lumpur, Malaysia ...

  13. A Business Sits on Relationship:A Reflective Analysis of Previous Working Experience

    Institute of Scientific and Technical Information of China (English)

    Wang Lin

    2015-01-01

    This article is a case of study of the marketing strategy of Hua Sheng Da Zipper Manufacturing Company. This company is an example of small private enterprise trying to survive through the fierce competition all over China. By analyzing its market, this paper tries to demonstrate the mechanism of relationship in Chinese business context.

  14. Stimulation of artemisinin biosynthesis in Artemisia annua hairy ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-06-07

    Jun 7, 2010 ... Ben Zhang1, Ting Zou1, Yan Hua Lu2 and Jian Wen Wang1, 2*. 1School of ... application of large-scale cultures of A. annua hairy root is still be ... high performance liquid chromatography; FTIR, fourier ... the ratio between the direct reducing sugar and total reducing sugar ... dissolved in 2 ml ethanol.

  15. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 257-266 Full Papers ... complexes of rhodium - Synthesis, structure and, spectral and electrochemical properties ... pp 267-273 Full Papers ... pp 275-281 Full Papers ... Yuliang Che Hua Yang Hongxiao Jin Chunxin Lu Ziyang Liu ... Excited state dynamics of 9,9'-bianthryl in room temperature ionic liquids as revealed by ...

  16. 15 CFR Supplement No. 7 to Part 748 - Authorization Validated End-User (VEU): List of Validated End-Users, Respective Items Eligible...

    Science.gov (United States)

    2010-01-01

    ... (West Area), Chengdu, China 611731. Shanghai Hua Hong NEC Electronics Company, Ltd 1C350.c.3; 1C350.d.7; 2B230; 2B350.d.2 2B350.g.3 2B350.i.4; 3B001.c.2; 3C002; 3C004 Headquarters and Fab. 1 of HHNEC, No. 1188...

  17. Jahan et al., Afr J Tradit Complement Altern Med. (2015) 12(4):134 ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    Nusrat Jahan 1, Md. Asiful Islam 2, Fahmida Alam 2, Siew Hua Gan 2* and Md. Ibrahim Khalil 1, 2*. 1 Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh,. 2 Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, ...

  18. African Journal of Biotechnology - Vol 11, No 55 (2012)

    African Journals Online (AJOL)

    Folic acid supplementation is not the sole factor in determining neural tube defects: The possible role of autoantibodies · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Keat Wei Loo, Siew Hua Gan, 11767-11771 ...

  19. Folic acid supplementation is not the sole factor in determining ...

    African Journals Online (AJOL)

    Folic acid supplementation is not the sole factor in determining neural tube defects: The possible role of autoantibodies. Keat Wei Loo, Siew Hua Gan. Abstract. Neural tube defects (NTDs) are severe but common congenital malformations. Neonates who suffer from NTDs may experience long-term complications throughout ...

  20. People’s Republic of China Scientific Abstracts, Number 173.

    Science.gov (United States)

    1977-08-03

    method, and the PCA reaction suppressing action of disodium chromoglycate and the sapo - ninum of Shao-nien-hung (Ardisia alyxiacfolia Tsiang.) The...element is its sapo - ninum, which is highly toxic, but the toxicity of its acetylated and hydrolytic product is much less. AUTHOR: CH’EN Ti-hua [7II5

  1. 75 FR 12748 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-03-17

    ... Shipping & Logistics, LLC, 10651 SW. 108 Avenue, 3A, Miami, FL 33176, Officers: Lorenzo A. Macias... Castleton Street, 263, City of Industry, CA 91748, Officers: Hua Yang, Vice President, (Qualifying Individual), Zhenfen Wu, Chairman. Qingfeng Wang dba Global Intertrans Logistics, 200 East Norwood Place, San...

  2. Cheng et al., Afr J Tradit Complement Altern Med. (2015) 12(4):72 ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    At the advanced stage of hepatic carcinoma, most ... The treatment combination of Chinese medical formula is more in line with the principle for cancer therapy, and studies have shown ... Ciji Hua'ai Baosheng Formula (CHBF) is composed of Dangshen (Radix Codonopsis) 12g (product lot No.130914), Pingbeimu (Bulbus.

  3. Note on the chemotaxonomy of Huaceae

    NARCIS (Netherlands)

    Beijersbergen, A.

    1972-01-01

    A comparative study of acetone, ethanol, and hydrolysis extracts of Hua gahonii Pierre ( Bos 6677, leaves) and Afrostyrax lepidophyllus Mildbr. (Brookman Amissah s.n., bark) has been carried out. The presence of the following compounds could not be demonstrated: gallic acid, ellagic acid,

  4. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. Jain Fang Gui. Articles written in Journal of Genetics. Volume 89 Issue 2 August 2010 pp 163-171 Research Article. Chromosomal localization of rDNA genes and genomic organization of 5S rDNA in Oreochromis mossambicus, O. urolepis hornorum and their hybrid · Hua Ping Zhu Mai ...

  5. State-of-the-art technologies of forest inventory and monitoring in Taiwan

    Science.gov (United States)

    Fong-Long Feng

    2000-01-01

    Ground surveys, remote sensing (RS), global positioning systems (GPS), geographic information systems (GIS), and permanent sampling plots (PSP) were used to inventory and monitor forests in the development of an ecosystem management plan for the island of Taiwan. While the entire island has been surveyed, this study concentrates on the Hui-Sun and Hsin-Hua Experimental...

  6. 78 FR 7455 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Heterogeneous...

    Science.gov (United States)

    2013-02-01

    ... DEPARTMENT OF JUSTICE Antitrust Division Notice Pursuant to the National Cooperative Research and... Tsing Hua University, Hsinchu, Taiwan, PEOPLE'S REPUBLIC OF CHINA; Ceva Inc., Mountain View, CA... the Act. The Department of Justice published a notice in the Federal Register pursuant to Section 6(b...

  7. Jiwen Xu

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. JIWEN XU. Articles written in Bulletin of Materials Science. Volume 37 Issue 4 June 2014 pp 895-902. Structural evolution, electrical and optical properties of AZO films deposited by sputtering ultra-high density target · Jiwen Xu Zupei Yang Hua Wang Xiaowen Zhang.

  8. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Cheng-Li Yao. Articles written in Journal of Chemical Sciences. Volume 121 Issue 1 January 2009 pp 89-93 Full Papers. Sucrose/bovine serum albumin mediated biomimetic crystallization of calcium carbonate · Cheng-Li Yao Wang-Hua Xu Ai-Min Ding Jin-Mao Zhu.

  9. Untitled

    Indian Academy of Sciences (India)

    are in conformity with the fact that, because of anharmonocity, the vibrational spacings and other properties of diatomic molecules 2,7,8} are explained mainly by the outer limb of the potential curve. 4. Conclusion. FP potential function of Wei Hua can be used to predict dissociation energy of the electronic states of diatomic ...

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. LING YANG. Articles written in Bulletin of Materials Science. Volume 36 Issue 3 June 2013 pp 389-393. Effects of Bi doping on dielectric and ferroelectric properties of PLBZT ferroelectric thin films synthesized by sol–gel processing · Hua Wang Li Liu Ji-Wen Xu Chang-Lai Yuan ...

  11. Evaluation of essential oil composition and DNA diversity of mint ...

    African Journals Online (AJOL)

    use

    2011-11-23

    Nov 23, 2011 ... Full Length Research Paper. Evaluation of essential oil composition and DNA diversity of mint resources from China. Chen Xiao Hua, G. R. Wang and Yao Lei*. Aromatic Plant R&D Centre, School of Agriculture and Biology, Shanghai Jiao Tong University Shanghai 200240, China. Accepted 19 September ...

  12. A double inequality for bounding Toader mean by the centroidal mean

    Indian Academy of Sciences (India)

    Annual Meetings · Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Proceedings – Mathematical Sciences; Volume 124; Issue 4. A double inequality for bounding Toader mean by the centroidal mean. Yun Hua Feng Qi.

  13. A double inequality for bounding Toader mean by the centroidal mean

    Indian Academy of Sciences (India)

    A double inequality for bounding Toader mean by the centroidal mean. YUN HUA1,∗ and FENG QI2. 1Department of Information Engineering, Weihai Vocational College, Weihai City,. Shandong Province 264210, China. 2College of Mathematics, Inner Mongolia University for Nationalities, Tongliao City,. Inner Mongolia ...

  14. Perisoreus infaustus

    Indian Academy of Sciences (India)

    avian genome evolution from cross-species amplification tests. MENG-HUA LI* ..... We tested for Hardy-. Weinberg equilibrium and linkage disequilibrium (LD) using ... 12 loci, two loci (Ase50 and Phtr3) were assigned to the Z- chromosome by ...

  15. Canine urolithiasis: A look at over 16 000 urolith submissions to the Canadian Veterinary Urolith Centre from February 1998 to April 2003

    Science.gov (United States)

    2004-01-01

    Abstract The purpose of this study was to report on the age, sex, breed, and mineral composition of 16 647 canine bladder uroliths submitted to the Canadian Veterinary Urolith Centre between February 1998 and April 2003. Each urolith submission was accompanied by a questionnaire. Of the submissions, approximately 43.8% were struvite and 41.5% oxalate. Struvite uroliths were most common in female dogs. Mixed breed dogs predominated, followed by the shih tzu, bichon frise, miniature schnauzer, Lhasa apso, and Yorkshire terrier. Oxalate uroliths were most common in males and in the miniature schnauzer, bichon frise, Lhasa apso, shih tzu, and Yorkshire terrier. Urate uroliths were most common in male Dalmations. Other urolith types, including cystine, xanthine, silica, and calcium phosphate, were less commonly reported. A review of risk factors for the various uroliths is presented, along with some recommendations for treatment and prevention. PMID:15072194

  16. Role of relative humidity in controlling rate of aflatoxin contamination in certain medicinal herbs under prolonged storage

    International Nuclear Information System (INIS)

    Elbazza, Z.E.; Mahmoud, M.I.; Roushdy, H.M.; Farrag, H.A.; Tablawy, S.Y.E.I.

    1995-01-01

    The effect of water activity on growth of aspergillus flavus test strain and aflatoxin production was studied in sabouraoud's yeast broth regulated with glycerol. Aflatoxin production increased with increasing the a w . The minimal a w was 0.92 for fungal growth and aflatoxins production. Growth of A.flavus test strain and aflatoxin production at 26+- I o and two relative humidities of 85% and 92.9% along four months incubation period on caraway, khlla, shih balady and wild chamomile samples were investigated. At 92.9% Rh, growth of A.flavus on caraway and khella samples was noticed after 20 days of incubation and increased with time incubation and increased with time. Aflatoxin production was detected after 30 days and decreased with prolonged incubation. Fungal growth and aflatoxin production were not observed on shih balady and wild chamomile samples at 92.9% Rh, and on the for studied herbs at 85%, Rh. 3 tabs

  17. Lipid Membrane Encapsulation of a 3D DNA Nano Octahedron.

    Science.gov (United States)

    Perrault, Steven D; Shih, William M

    2017-01-01

    Structural DNA nanotechnology methods such as DNA origami allow for the synthesis of highly precise nanometer-scale materials (Rothemund, Nature 440:297-302, 2006; Douglas et al., Nature 459:414-418, 2009). These offer compelling advantages for biomedical applications. Such materials can suffer from structural instability in biological environments due to denaturation and nuclease digestion (Hahn et al., ACS Nano 2014; Perrault and Shih, ACS Nano 8:5132-5140, 2014). Encapsulation of DNA nanostructures in a lipid membrane compartmentalizes them from their environment and prevents denaturation and nuclease digestion (Perrault and Shih, ACS Nano 8:5132-5140, 2014). Here, we describe the encapsulation of a 50 nm DNA nanostructure having the geometry of a wireframe octahedron in a phospholipid membrane containing poly-(ethylene glycol), resulting in biocompatible DNA nanostructures.

  18. Supersymmetry Breaking, Gauge Mediation, and the LHC

    International Nuclear Information System (INIS)

    Shih, David

    2015-01-01

    Gauge mediated SUSY breaking (GMSB) is a promising class of supersymmetric models that automatically satisfies the precision constraints. Prior work of Meade, Seiberg and Shih in 2008 established the full, model-independent parameter space of GMSB, which they called 'General Gauge Mediation' (GGM). During the first half of 2010-2015, Shih and his collaborators thoroughly explored the parameter space of GGM and established many well-motivated benchmark models for use by the experimentalists at the LHC. Through their work, the current constraints on GGM from LEP, the Tevatron and the LHC were fully elucidated, together with the possible collider signatures of GMSB at the LHC. This ensured that the full discovery potential for GGM could be completely realized at the LHC.

  19. Neutral endopeptidase up-regulation in isolated human umbilical artery: involvement in desensitization of bradykinin-induced vasoconstrictor effects.

    Science.gov (United States)

    Pelorosso, Facundo Germán; Halperin, Ana Verónica; Palma, Alejandro Martín; Nowak, Wanda; Errasti, Andrea Emilse; Rothlin, Rodolfo Pedro

    2007-02-01

    Previous reports show that bradykinin B(2) receptors mediate contractile responses induced by bradykinin (BK) in human umbilical artery (HUA). However, although it has been reported that BK-induced responses can desensitize in several inflammatory models, the effects of prolonged in vitro incubation on BK-induced vasoconstriction in HUA have not been studied. In isolated HUA rings, BK-induced responses after a 5-h in vitro incubation showed a marked desensitization compared with responses at 2 h. Inhibition of either angiotensin-converting enzyme (ACE) or neutral endopeptidase (NEP), both BK-inactivating enzymes, failed to modify responses to BK at 2 h. After 5 h, ACE inhibition produced only a slight potentiation of BK-induced responses. In contrast, BK-induced vasoconstriction at 5 h was markedly potentiated by NEP inhibition. Moreover, NEP activity, measured by hydrolysis of its synthetic substrate (Z-Ala-Ala-Leu-p-nitroanilide), showed a 2.4-fold increase in 5-h incubated versus 2-h incubated tissues, which was completely reversed by cycloheximide (CHX) treatment. Furthermore, CHX significantly potentiated BK-induced responses, suggesting that NEP-mediated kininase activity increase at 5 h depends on de novo protein synthesis. In addition, under NEP inhibition, CHX treatment failed to produce an additional potentiation of BK-induced vasoconstriction. Still, NEP up-regulation was confirmed by Western blot, showing a 2.1-fold increase in immunoreactive NEP in 5-h incubated versus 2-h incubated HUA. In summary, the present study provides strong pharmacological evidence that NEP is up-regulated and plays a key role in desensitization of BK-induced vasoconstriction after prolonged in vitro incubation in HUA. Our results provide new insights into the possible mechanisms involved in BK-induced response desensitization during sustained inflammatory conditions.

  20. A Network Analysis of the Teachers and Graduate Students’ Research Topics in the Field of Mass Communication

    OpenAIRE

    Ming-Shu Yuan; Yung-Nan Yu

    2013-01-01

    The completion of a master’s thesis requires the advisor’s guidance on topic selection, data collection, analysis, interpretation and writing. The advisory committee’s input also contributes to the work. This study conducted content analysis and network analysis on a sample of 547 master’s theses from eight departments of the College of Journalism and Communications of Shih Hsin University to examine the relationships between the advisors and committee members as well as the connections of re...

  1. Prevention of Ovarian High Grade Serous Carcinoma by Elucidating Its Early Changes

    Science.gov (United States)

    2016-10-01

    Cancer Res, in press. PMID: 27590741 31. Ayhan A, Kuhn E, Wu RC, Ogawa H, Talbott AB, Mao TL, Sugimura H, Shih IM, Wang TL. CCNE1 copy number gain...most significant focal DNA somatic copy number alterations were shared between cases with and without STIC lesions. Class comparison of the RNA...significant effort has been placed on determining the menstrual status of samples collected – this included reviewing the endometrium of corresponding

  2. High Seas Buffer: The Taiwan Patrol Force, 1950-1979

    Science.gov (United States)

    2012-04-01

    It is prohibited to use NWC’s logo on any republication of this book without the express, written permission of the Editor, Naval War College Press, or...watches and developed an English–Chinese signal book to be used in communications between American and Nationalist ships. With the help of foreign... secondhand from Belgium, Canada, Denmark, Germany, and Japan. One of their primary missions was to patrol the strait. On 13 January 1967, Maj. Shih-Lin Hu

  3. Monoamine Oxidase A: A Novel Target for Progression and Metastasis of Prostate Cancer

    Science.gov (United States)

    2015-12-01

    dye* Corresponding author. Uro -Oncology Research Pr Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, E-mail address: Leland.Chung@cshs.org (L.W.K...INVESTIGATOR: Jean C. Shih, Ph.D. CONTRACTING ORGANIZATION: University of Southern California Los Angeles, CA 90089-0001 REPORT DATE: December 2015...SOUTHERN CALIFORNIA 3720 S. FLOWER STREET LOS ANGELES, CA 90089-0001 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S

  4. Researcher might have found answer to 'birth of the universe'

    CERN Multimedia

    2003-01-01

    A National Taiwan University (NTU) research team has discovered a new physical phenomenon that could challenge the well-accepted theory about the birth of the universe. However,Lee Shih-chang, a researcher at Academia Sinica's Institute of Physics, said the new scientific research results will be accepted only after an academic paper detailing the research process and conclusions is released and the research results are verified by experts in the field.

  5. Contribution of Fuzzy Minimal Cost Flow Problem by Possibility Programming

    OpenAIRE

    S. Fanati Rashidi; A. A. Noora

    2010-01-01

    Using the concept of possibility proposed by zadeh, luhandjula ([4,8]) and buckley ([1]) have proposed the possibility programming. The formulation of buckley results in nonlinear programming problems. Negi [6]re-formulated the approach of Buckley by the use of trapezoidal fuzzy numbers and reduced the problem into fuzzy linear programming problem. Shih and Lee ([7]) used the Negi approach to solve a minimum cost flow problem, whit fuzzy costs and the upper and lower bound. ...

  6. Bio-Inspired Nanomaterials: Protein Cage Nano-Architectures

    Science.gov (United States)

    2008-04-01

    Shevchenko, A. Weizsacker, F. (2004). Hepatitis B virus nucleocapsids (2003). Fast-response proteomics by accelerated in-gel formed by carboxy-terminally...Newman, M. & Shih, C. sin. Proteomics , 5, 2319-2321. (2005). Exposure of RNA templates and encapsidation 60. Prudova, A., Bauman, Z., Braun, A...isolated from the fungus Dactylium dendroides [I]. It is H334, Y329, G513, and T580) and water molecules. composed of three distinct domains, organized

  7. A Quantum Network with Atoms and Photons

    Science.gov (United States)

    2016-09-01

    98, 111115. 5. Karmakar, S, Shih, Y. Two- color ghost imaging with enhanced angular resolving power. Physical Review A. 2010; 81, 033845. 6. Karmakar...information. We constructed the rubidium (⁸⁷Rb) atomic memory magneto optical trap (MOT) cell and laser controls, and developed protocols, hardware, and...software to control the secure teleportation of information between quantum memories at ARL and JQI. Notably, we performed successful in-laboratory

  8. Sustained release of vancomycin from novel biodegradable nanofiber-loaded vascular prosthetic grafts: in vitro and in vivo study

    OpenAIRE

    Liu, Kuo-Sheng; Lee, Cheng-Hung; Wang, Yi-Chuan; Liu, Shih-Jung

    2015-01-01

    Kuo-Sheng Liu,1 Cheng-Hung Lee,2 Yi-Chuan Wang,3 Shih-Jung Liu3 1Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan; 2Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan; 3Department of Mechanical Engineering, Chang Gung University, Tao-Yuan, Taiwan Abstract: This study describes novel biodegradable, drug-eluting nanofiber-loaded vascular prosthetic grafts that provide local and sustained...

  9. Two-stage estimation in copula models used in family studies

    DEFF Research Database (Denmark)

    Andersen, Elisabeth Anne Wreford

    2005-01-01

    by Shih and Louis (Biometrics vol. 51, pp. 1384-1399, 1995b) and Glidden (Lifetime Data Analysis vol. 6, pp. 141-156, 2000). Because register based family studies often involve very large cohorts a method for analysing a sampled cohort is also derived together with the asymptotic properties...... of the estimators. The proposed methods are studied in simulations and the estimators are found to be highly efficient. Finally, the methods are applied to a study of mortality in twins....

  10. JPRS Report East Asia Southeast Asia

    Science.gov (United States)

    1987-06-05

    31 Mar 87) 20 Palm Oil Industry Promotion Moves Proposed (Lim Hock Chye ; BUSINESS TIMES, 1 May 87) .. 22 Paper Comments on 5th Malaysia Plan...1 [Article by Lim Hock Chye ] [Text] A GOVERNMENT-INDUSTRY committee has recommended the Implementation of several measures to strengthen the...stopped due to lack of funds for providing subsidies. According to Deputy Education Minister (Yun Shih- Chin ), Chinese-language classes in several

  11. Radiology examination as a diagnostic aid in presentations with ...

    African Journals Online (AJOL)

    Radiology examination as a diagnostic aid in presentations with wide differential diagnoses: Case report of new Hodgkin's lymphoma on a background of poorly controlled HIV. Rachel Hubbard, Jalpa Kotecha, Thomas Nash, Yu Jin Lee, Nasir Khan, Farhat Kazmi ...

  12. How should we buy books today? A librarian’s view of collection development

    OpenAIRE

    Yu, Haixian

    2013-01-01

    Mr. YU Haixian, East China Normal University Library, presented at the International Forum "Developments in Publishing and their Implications for Library Resource Building" (Session 2), Chinese Library Annual Conference, November 7, 2013.

  13. Scymnus camptodromus (Coleoptera: Coccinellidae) larval development and predation of hemlock woolly adelgid (Hemiptera: Adelgidae)

    Science.gov (United States)

    Samita Limbu; Melody A. Keena; David Long; Nancy Ostiguy; Kelli. Hoover

    2015-01-01

    Development time and prey consumption of Scymnus (Neopullus) camptodromus Yu and Liu (Coleoptera: Coccinellidae) larvae by instar, strain, and temperature were evaluated. S. camptodromus, a specialist predator of hemlock woolly adelgid Adelges tsugae (Annand) (Hemiptera:...

  14. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Jing-Ping Wang1 Hong-Yu Niu1 Jing-Yang Niu1. Institute of Molecular and Crystal Engineering, School of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475001, PR China ...

  15. Probability to produce animal vaccines in insect baculovirus ...

    African Journals Online (AJOL)

    Administrator

    2011-09-07

    Sep 7, 2011 ... The insect baculovirus expression system is a valuable tool for the production of vaccine. .... vaccine expression/delivery vehicle (Yu-Chen et al., ... baculoviruses are applied in cell-based assays for drug ... Intramuscular.

  16. Graph-based unsupervised feature selection and multiview ...

    Indian Academy of Sciences (India)

    2015-09-28

    Sep 28, 2015 ... is presented by Yu et al. (2010) to retrieve biomedical ... dimensional microarray data, still require further research to be done in this topic .... relatively aggressive and require therapy soon after diagnosis or else patient dies ...

  17. 1,6-Diaminoperylene bisimide with a highly twisted perylene core

    Indian Academy of Sciences (India)

    ... KEW-YU CHEN. ∗. Department of Chemical Engineering, Feng Chia University, 40724 Taichung, Taiwan, Republic of China ... chromic materials,6 and organic field-effect transis- ..... Wasielewski M R 2012 Competition between singlet fis-.

  18. Effects of the Consortium of Pseudomonas, Bacillus and ...

    African Journals Online (AJOL)

    BSN

    Microbiology Department, Anambra State University, Uli. Abstract. The effect ... physical parameters of crude oil (Atlas, 1981). It is known that ..... Ecology, ASTM, Philcidelphia, PA.pp. 196-204. ... Wang, X., X. Yu, and Bartha, R. (1990). Effect of.

  19. Stress in Humanitarian Workers

    African Journals Online (AJOL)

    user

    recognized as one of the most serious occupational health hazards reducing workers' satisfaction and productivity,. 1-3 ... Using a self- ... Kan D, Yu X. Occupational Stress, Work-Family. Conflict and Depressive Symptoms among Chinese.

  20. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Jizheng Huang1 Yu Liu2. College of Sciences, North China University of Technology, Beijing 100144, People's Republic of China; School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, China ...

  1. Christianity and Community development in Igboland, 1960-2000

    African Journals Online (AJOL)

    FEN

    developed countries with inadequate impact assessment locally and the lack of appropriate entry ... corporations at the cost of poor society.Fundamentally, least ...... Crime and Delinquency, volume 41, number 2, pp.180-213. Yu, P. (2010).

  2. 75 FR 69158 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2010-11-10

    ... Lenore Louit Nicolas Paul Low Elizabeth Lowrie Marcia Lu Chun Ching Luntz Reagan Mather Lusser Christoph... Chi Tan Yenny Jacques G. Yenny Monique Y. Yokokawa Jun Yu Pearl Zang Wenyi Zedan Mohamed F. Zeinalzade...

  3. Significant improvement of electrochemical performance of Cu ...

    Indian Academy of Sciences (India)

    LiVPO4F cathode material for lithium-ion batteries. YU ZHANGa,∗, XIAOLAN BAIb ... and energy dispersive spectroscopy (EDS). ... Analysis of electrochemical impedance spectra (EIS) ... studied with a SEM (JSM-7500F, Japan) equipped with.

  4. 86 Optimisation du dimensionnement des systèmes photovoltaïques ...

    African Journals Online (AJOL)

    REMI

    This paper is treated a comparison of the energy received by solar panels using two ..... [20] - TAO YU and GUO WENCHENG, Study on tracking strategy of automatic ... on CPV Generation, 2010 International Conference on Intelligent System ...

  5. Hiina naiskunstnike näitus / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2001-01-01

    Hongkongis avatud näitus "Hiina kunstilaval" keskendub hiina naiskunstnike Yu Cheni, Wang Jingi, Yuen Nimchi ja Hao Li loomingule ning on esimene samm võitluses hiina naiskunstnike soolise diskrimineerimise vastu.

  6. Multiple oncogenic roles of nuclear ß-catenin

    Indian Academy of Sciences (India)

    Raju Kumar

    2017-10-26

    Oct 26, 2017 ... mote tumour growth in prostate cancer (Pearson et al. 2009;. Yu et al. ... scriptional induction of specific genes involved in both melanocyte and ..... infiltration response against tumour antigens in mouse model of melanoma ...

  7. Enhancement of Diosgenin Production in Plantlet and Cell Cultures ...

    African Journals Online (AJOL)

    Enhancement of Diosgenin Production in Plantlet and Cell Cultures of Dioscorea zingiberensis by Palmarumycin C13 from the Endophytic fungus, Berkleasmium sp. Dzf12. Y Mou, K Zhou, D Xu, R Yu, J Li, C Yin, L Zhou ...

  8. 英文摘要

    Institute of Scientific and Technical Information of China (English)

    2017-01-01

    Monetary Policy, Excessive Investment and Financial Distress Ran Yu Li Bingcheng (Accounting School, Guizhou University of Finance and Economics; School of Accounting, Zhongnan University of Economics and Law)

  9. Antibacterial and antifungal effect of high pH and paraffin wax ...

    African Journals Online (AJOL)

    GREGO

    2007-03-19

    Mar 19, 2007 ... Determination of antibacterial and antifungal activity of the combined treatments was achieved by ... or control the growth and activities of spoilage microor- .... Kawo AH, Bassey SE, Aliyu YU (2005): Bacteriological Quality of.

  10. On the Lp affine isoperimetric inequalities

    Indian Academy of Sciences (India)

    surface area measure on convex bodies. We also establish the reverse version of -Petty projection inequality and an affine isoperimetric inequality of − p K . Author Affiliations. Wuyang Yu1 Gangsong Leng2. Institute of Management Decision ...

  11. Genes involved in sex determination process and the influence of ...

    African Journals Online (AJOL)

    DR. & MRS. TONY A. NLEWADIM

    2015-02-04

    Feb 4, 2015 ... Key words: Next-generation sequencing, simple sequence repeats, Rhamdia sp. .... individual genotypes were defined according to the standards of the bands. ..... Wang J, Yu X, Zhao K, Zhang Y, Tong J, Peng Z (2012).

  12. Depression among Congestive Heart Failure Patients: Results of a Survey from Central China

    Directory of Open Access Journals (Sweden)

    JPMS

    2011-10-01

    Full Text Available Tabish Hussain, Li Yu Shu, Xiang Cheng, Tumenjavkhlan Sosorburam, A.Seid Adji, Sara Tajammul, Aamra Sartaj (Union Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan, China (pages 38-42

  13. A study of formation of iron nanoparticles in aluminium matrix with helium pores

    Czech Academy of Sciences Publication Activity Database

    Kichanov, S.E.; Kozlenko, D. P.; Belushkin, A.V.; Reutov, V.F.; Samoilenko, S.O.; Jirák, Zdeněk; Savenko, B. N.; Bulavin, L. A.; Zubavichus, Y.V.

    2012-01-01

    Roč. 351, č. 1 (2012), "012013-1"-"012013-5" ISSN 1742-6588. [International Workshop on SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor - Devoted to the 75th anniversary of Yu M Ostanevich's Birth /2./. Dubna, 27.05.2011-30.05.2011] Institutional research plan: CEZ:AV0Z10100521 Keywords : iron nanoparticles * aluminium matrix * helium pores Subject RIV: BM - Solid Matter Physics ; Magnetism

  14. Right Sizing the People’s Liberation Army: Exploring the Contours of China’s Military

    Science.gov (United States)

    2007-09-01

    Diyuan yu Zhongguo Haijun Jianshe” (“Stratgeic Geography and the Development of China’s Navy”), Shijie Jingji yu Zhengzhi (World Economics and...on conventional [missile forces] (hechang jianbei, yi chang wei zhu ); • Bring out focal points, put priority on quality (tuchu zhongdian, zhiliang...Juece” [“2nd Artillery Command & Control Decision- Making During a Joint Campaign”], Junshi Xueshu, July 2004, p. 65. 30. Shang Yi, “ Zhu Chenghu

  15. Right-Sizing the People’s Liberation Army: Exploring the Contours of China’s Military

    Science.gov (United States)

    2007-09-01

    yu Zhongguo Haijun Jianshe" ("Stratgeic Geography and the Development of China’s Navy"), Shijie Jingji yu Zhengzhi (World Economics and Politics...They are: "* Maintain conventional and nuclear [missile forces], but put priority on conventional [missile forces] (hechang jianbei, yi chang wei zhu ...Zuozhan Zhihui Juece" [Ŗnd Artillery Command & Control Decision- Making During a Joint Campaign"], Junshi Xueshu, July 2004, p. 65. 30. Shang Yi, " Zhu

  16. The promise of cyborg intelligence.

    Science.gov (United States)

    Brown, Michael F; Brown, Alexander A

    2017-03-01

    Yu et al. (2016) demonstrated that algorithms designed to find efficient routes in standard mazes can be integrated with the natural processes controlling rat navigation and spatial choices, and they pointed out the promise of such "cyborg intelligence" for biorobotic applications. Here, we briefly describe Yu et al.'s work, explore its relevance to the study of comparative cognition, and indicate how work involving cyborg intelligence would benefit from interdisciplinary collaboration between behavioral scientists and engineers.

  17. Prompt Global Strike: China and the Spear

    Science.gov (United States)

    2014-04-01

    Network Centric Warfare), Feihang Daodan (Winged Missiles Journal), Issue 11, November 2006, pp. 18-21; Ou Nancheng, Feng Shuxing, and Cao Yuhua are...affiliated with China’s Liberation Army Equipment Institute. Ou Nancheng, Feng Shuxing, and Cao Yuhua , “Kuaisu quanqiu daji xitong yu kongtian xinxi...Shuxing, and Cao Yunhua are affiliated with the PLA Armaments Institute. Ou Nancheng, Feng Shuxing, and Cao Yuhua , “Kuaisu quanqiu daji xit