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Sample records for shaw avenue pittsburgh

  1. Shaw on Hamlet

    Dukore, Bernard F.

    1971-01-01

    Shaw's preoccupation with Hamlet resonates in his creative writing. Article documents this statement not only by examining his novels and plays but by searching through prefaces, postscripts, reviews, letters, speeches, etc. that span Shaw's lifetime. (Author/RB)

  2. Pittsburgh Fish Fry Locations

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Lenten Fish Fry records for the Greater Pittsburgh region. Data is collected before and during the Lenten fish fry season each year by Code for Pittsburgh. Data is...

  3. Pittsburgh Police Arrest Data

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Arrest data contains information on people taken into custody by City of Pittsburgh police officers. More serious crimes such as felony offenses are more likely to...

  4. Pittsburgh City Facilities

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Pittsburgh City FacilitiesIncludes: City Administrative Buildings, Police Stations, Fire Stations, EMS Stations, DPW Sites, Senior Centers, Recreation Centers, Pool...

  5. City of Pittsburgh Trees

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Trees cared for and managed by the City of Pittsburgh Department of Public Works Forestry Division. Tree Benefits are calculated using the National Tree Benefit...

  6. Jenny Avenue

    Cyrille Weine

    2012-05-01

    Full Text Available

    There still are, at the periphery of urban centers, timeless and fragile places. Beside the growth, life has arranged places of rest. Ageless buildings, alongside roses, hedges protecting privacy, tables that knew the absinthe ... There are also vehicle ponds, rubbish and weeds. The city grows, preceded by letters of expropriation and its attendant hassles, dramas and uprootings. The framework of lifetimes is promised to total and brutal destruction.

    A site full of life and desire. Men there are free, but they also face danger. Soon, developers will chase them. A space of choice, of freewill, exchange and sharing, respect and civility. An area rare and fragile, which reality will reduce to a memory. Children can do nothing. One day soon, they will go, all turning a page in their lives.

    The Jenny Avenue in Nanterre seals the border between the suburbian cities of Nanterre and Courbevoie, near la Defence. A property development project in Courbevoie, site of the residence Villapollonia, disrupts the landscape and uses the nanterrian suburban neighborhood.

    A striking contrast between urban forms and cultures.

  7. Pittsburgh PLI Violations Report

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Report containing Department of Permits, Licenses, and Inspections violation notices that have been issued by the City after October 15, 2015

  8. Immunology in Pittsburgh.

    Finn, Olivera J; Salter, Russell D

    2006-01-01

    The University of Pittsburgh School of Medicine has a long tradition of excellence in immunology research and training. Faculty, students, and postdoctoral fellows walk through hallways that are pictorial reminders of the days when Dr. Jonas Salk worked here to develop the polio vaccine, or when Dr. Niels Jerne chaired the Microbiology Department and worked on perfecting the Jerne Plaque Assay for antibody-producing cells. Colleagues and postdoctoral fellows of Professor Salk are still on the faculty of the University of Pittsburgh Medical School as are graduate students of Professor Jerne. A modern research building, the 17 story high Biomedical Science Tower, is a vivid reminder of the day when Dr. Thomas Starzl arrived in Pittsburgh and started building the most prominent solid-organ-transplant program in the world. The immunology research that developed around the problem of graft rejection and tolerance induction trained numerous outstanding students and fellows. Almost 20 yr ago, the University of Pittsburgh founded the University of Pittsburgh Cancer Institute (UPCI) with the renowned immunologist Dr. Ronald Herberman at its helm. This started a number of new research initiatives in cancer immunology and immunotherapy. A large number of outstanding young investigators, as well as several well-established tumor immunologists, were recruited to Pittsburgh at that time.

  9. Our Pittsburgh Constellation

    Turnshek, Diane

    2015-08-01

    Riding on the Pittsburgh mayor’s keen interest in astronomy and the ongoing change of 40,000 city lights from mercury and sodium vapor to shielded LEDs, we organized a series of city-wide celestial art projects to bring attention to the skies over Pittsburgh. Light pollution public talks were held at the University of Pittsburgh’s Allegheny Observatory and other colleges. Earth Hour celebrations kicked off an intensive year of astronomy outreach in the city. Lights went out on March 28, 2015 from 8:30 to 9:30 pm in over fifty buildings downtown and in Oakland (the “Eds and Meds” center, where many Pittsburgh universities and hospitals are located). Our art contest was announced at the De-Light Pittsburgh celebration at the Carnegie Science Center during Astronomy Weekend. “Our Pittsburgh Constellation” is an interactive Google map of all things astronomical in the city. Different colored stars mark locations of planetariums, star parties, classes, observatories, lecture series, museums, telescope manufacturers and participating art galleries. Contest entrants submitted artwork depicting their vision of the constellation figure that incorporates and connects all the “stars” in our custom city map. Throughout the year, over a dozen artists ran workshops on painting star clusters, galaxies, nebulae, comets, planets and aurorae with discussions of light pollution solutions and scientific explanations of what the patrons were painting, including demonstrations with emission tubes and diffraction grating glasses. We will display the celestial art created in this International Year of Light at an art gallery as part of the City’s Department of Innovation & Performance March 2016 Earth Hour gala. We are thankful for the Astronomical Footprint grant from the Heinz Endowments, which allowed us to bring the worlds of science and art together to enact social change.

  10. Shaw's Comedy, Language Arts: 5113.90.

    Dade County Public Schools, Miami, FL.

    This guide provides the teacher with strategies to aid students in examining five representative plays by Bernard Shaw and in comparing his comedy with the comic art of Oscar Wilde, Richard Sheridan, Ben Jonson, and William Shakespeare. Performance objectives include isolating elements which pertain to the life and times of Shaw, delineating…

  11. Pittsburgh rainwater analysis by PIXE

    Chan, K C; Cohen, B L; Frohliger, J O; Shabason, L

    1976-01-01

    Concentrations of thirteen elements in rainwater from the Pittsburgh, Pa., area were analysed by Charged Particle Induced X-ray Emission (PIXE). They were compared to rainwater in a rural area and air particulates in Pittsburgh. Local and non-local contributions are discussed. Washout ratios were calculated and found to be larger for smaller size particles, contrary to general belief. The work demonstrates the convenience of using PIXE.

  12. A Community Profile of Pittsburgh Neighborhoods, 1974

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — These data include four historical datasets that were transcribed from the Community Profiles of Pittsburgh reports, which were published in 1974. The Community...

  13. Pittsburgh International Airport - Scheduled Passenger Traffic

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Here you can find Pittsburgh International Airport’s Monthly Scheduled Traffic Reports. Each of these reports contain a year-over-year (YOY) analysis of scheduled...

  14. Structure health assessment and warning system (SHAWS)

    Bock, Daniel M.; Kim, Keehoon; Mapar, Jalal

    2008-03-01

    We are developing a Structure Health Assessment and Warning System (SHAWS) based on building displacement measurements and wireless communication. SHAWS will measure and predict the stability/instability of a building, determine whether it is safe for emergency responders to enter during an emergency, and provide individual warnings on the condition of the structure. SHAWS incorporates remote sensing nodes (RSNs) installed on the exterior frame of a building. Each RSN includes a temperature sensor, a three-axis accelerometer making static-acceleration measurements, and a ZigBee wireless system (IEEE 802.15.4). The RSNs will be deployed remotely using an air cannon delivery system, with each RSN having an innovative adhesive structure for fast (<10 min) and strong installation under emergency conditions. Once the building has moved past a threshold (~0.25 in./building story), a warning will be issued to emergency responders. In addition to the RSNs, SHAWS will include a base station located on an emergency responder's primary vehicle, a PDA for mobile data display to guide responders, and individual warning modules that can be worn by each responder. The individual warning modules will include visual and audio indicators with a ZigBee receiver to provide the proper degree of warning to each responder.

  15. Environmental Survey preliminary report, Pittsburgh Energy Technology Center, Pittsburgh, Pennsylvania

    1988-09-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the US Department of Energy (DOE) Pittsburgh Energy Technology Center (PETC) conducted December 7--11, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team specialists are outside experts being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with PETC. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at PETC, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain environmental problems identified during its on-site Survey activities at PETC. The S A Plan will be executed by the Oak Ridge National Laboratory (ORNL). When completed, the Plan's results will be incorporated into the PETC Survey findings for inclusion into the Environmental Survey Summary Report. 64 refs., 23 figs., 29 tabs.

  16. Shaw Air Force Base Capital Improvement Program Environmental Assessment

    2010-05-01

    A FB Capital Im provem ent Program Environm ental A ssessm ent 3-21 Figure 3.6-1. W ater R esources at Shaw A FB under the Proposed A ction...Figure 3.6-2. W ater R esources at Shaw A FB under A lternative 1 0 Key c::::J Shaw!IFB C’l1 Proposed Project ~ Number -- Creek/Stream c:::::J w

  17. Pittsburgh Internet Service Providers By Block: June 2016

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Displays information about internet coverage in the City of Pittsburgh, as published by the Federal Communications Commission.

  18. Pittsburgh American Community Survey 2015, School Enrollment

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — School enrollment data are used to assess the socioeconomic condition of school-age children. Government agencies also require these data for funding allocations...

  19. Mass spectrometry at the Pittsburgh conference

    Borman, S.

    1987-01-01

    Each year analytical chemists flock to the Pittsburgh Conference to learn about the latest trends in analytical instrumentation. In this Focus, a number of prominent mass spectroscopists who attended this year's meeting in Atlantic City, NJ, discuss their perceptions of current developments in the field of mass spectrometry (MS). In the June 1 issue of Analytical Chemistry, the authors coverage of the Pittsburgh Conferences continues with a follow-up article on specific developments in hyphenated mass spectrometry - primarily liquid chromatography - MS (LC/MS) and gas chromatography - infrared spectrometry MS (GC/IR/MS)

  20. Pittsburgh, Pennsylvania: Solar in Action (Brochure)

    2011-10-01

    This brochure provides an overview of the challenges and successes of Pittsburgh, PA, a 2007 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

  1. Autonomous Vehicle Survey of Bicyclists and Pedestrians in Pittsburgh, 2017

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — In Pittsburgh, Autonomous Vehicle (AV) companies have been testing autonomous vehicles since September 2016. However, the tech is new, and there have been some...

  2. Pittsburgh International Airport - March 2018 Scheduled Passenger Traffic

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Attached is Pittsburgh International Airport’s Monthly Scheduled Traffic Report. This report contains a year-over-year (YOY) analysis of scheduled flights and...

  3. Pittsburgh International Airport - April 2018 Scheduled Passenger Traffic

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Attached is Pittsburgh International Airport’s Monthly Scheduled Traffic Report. This report contains a year-over-year (YOY) analysis of scheduled flights and...

  4. Pittsburgh International Airport - January 2018 Scheduled Passenger Traffic

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Attached is Pittsburgh International Airport’s Monthly Scheduled Traffic Report. This report contains a year-over-year (YOY) analysis of scheduled flights and...

  5. Pittsburgh International Airport - February 2018 Scheduled Passenger Traffic

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Attached is Pittsburgh International Airport’s Monthly Scheduled Traffic Report. This report contains a year-over-year (YOY) analysis of scheduled flights and...

  6. Electrokinetic Fingering In Hele-Shaw Cells

    Mirzadeh, Mohammad; Bazant, Martin

    2016-11-01

    Large scale flow problems in porous media, such as those encountered in underground oil reservoirs, are typically described by the Darcy's law. However, it is well known that many underground rock formations contain surface groups and minerals that dissociate in the presence of water. Convection of these charges by the pressure driven flow can then set up streaming current and streaming potential that affects the flow. Furthermore, electric fields that are often used to enhance oil recovery, e.g. by reducing the oil's viscosity through electro-thermal heating, drive electro-osmotic flows that could set up very large pressure in small pores. The full description of fluid flow thus requires a solution to the fully coupled electrokinetic problem. In their seminal work, Saffman and Taylor showed that the moving interface between two immiscible fluids in a porous medium becomes unstable if pushed by the low-viscosity fluid. Here we report on the role of electrokinetic phenomena on stability of these viscous fronts in Hele-Shaw cells by using analytic as well as numerical approaches. Interestingly, we find that the instability could be suppressed if the right physical conditions are met or otherwise enhanced, leading to greater mixing of two fluids.

  7. 75 FR 56866 - Special Local Regulation; Monongahela River, Pittsburgh, PA

    2010-09-17

    ... participants of the Pittsburgh Dragon Boat Festival from the hazards imposed by marine traffic. Entry into the... Pittsburgh Dragon Boat Festival from the hazards imposed by marine traffic, and re-scheduling the event is... the Pittsburgh Dragon Boat Festival from the hazards imposed by marine traffic. Discussion of Rule...

  8. The Wall On Gladstone Avenue

    Pina MARCHESE

    2012-12-01

    Full Text Available "Since the house is on fire, Let us warm ourselves..." (Calabrian Proverb It all began in the village. We would wake up with the sun, we would rest our laboured bodies underneath the moon. Gli vecchi (old folks often told us: "In the end, all that will remain is our story. Nothing else really matters." This article "The Wall On Gladstone Avenue" will take you into a life of duality and how immigrants "press-on" to acquire knowledge and manifest meaning in a new land Canada.

  9. MHD Hele-Shaw flow of Rivlin-Ericksen fluid

    Ghosh, B.C.; Sengupta, P.R.

    1995-01-01

    In this paper, an attempt has been made to study the MHD Hele-Shaw flow of Rivlin-Ericksen visco-elastic fluid assuming the pressure gradient to be proportional to exp (-nt). The velocity components are obtained and the effect of visco-elasticity is discussed on velocity components. (author). 8 refs

  10. George Bernard Shaw's "Androcles and the Lion": A Postmodernist Study

    Hooti, Noorbakhsh; Jeihouni, Mojtaba

    2012-01-01

    This study makes an attempt to analyze the manifold aspects of Shaw's "Androcles and the Lion" on a postmodernist standpoint, meanwhile, demonstrates the dominion of modernism, which is portrayed through the vehicle of comedy with a bitter ironic language through the play. Regardless of the historical period in which the play occurs, the…

  11. Pittsburgh 2013 Energy Baseline: Consumption, Trends & Opportunities

    Tarka, Thomas J. [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United States); James III, Robert E. [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United States); Withum, Jeffrey A. [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United States); Plowman, Brian [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United States); Shih, Chung Yan [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United States)

    2017-03-01

    The United States (U.S.) Department of Energy (DOE) and the National Energy Technology Laboratory (NETL) are working in conjunction with the City of Pittsburgh (City) to transform how energy is produced, transported, and consumed in the City. This transformation will rely on 21st Century Energy Infrastructure designs, which leverage advanced technology and design techniques to modernize energy infrastructure, create new business models and markets, and expand technology research and development opportunities. Achieving this vision will require developing solutions that are unique to the City: its climate, topography, energy needs, resources, and existing infrastructure.a In this way, the City will demonstrate what the American “City of the Future” looks like, with all its attendant environmental, economic, and job-creation benefits. It will also serve as a template for other cities seeking to reinvent their energy systems.

  12. Water resources of the Pittsburgh area, Pennsylvania

    Noecker, Max; Greenman, D.W.; Beamer, N.H.

    1954-01-01

    The per capita use of water in the Pittsburgh area in 1951 was 2, 000 gallons per day fgpd) or twice the per capita use in Pennsylvania as a whole. An average of about 3, 040 million gallons of water was withdrawn from the streams and from the ground each day. Of this amount, nearly 190 million gallons per day (mgd), or 6 percent, was for domestic public water supply. Industry, including public utilities generating steam for electric energy, used approximately 2, 900 mgd, of which about 42 mgd was purchased from public supply sources. In spite of this tremendous demand for water, a sufficient quantity was available to satisfy the needs of the area without serious difficulty. Acid mine drainage presents the greatest single pollution problem in the Pittsburgh area at the present time (1953) because no practical means has been found for its control. The waters of several of the rivers are strongly acid for this reason. Of the three major rivers in the area, Monongahela River waters have the greatest acid concentration and Allegheny River waters the least. Untreated domestic and industrial wastes are additional sources of stream pollution in the area. Much of the water is hard and corrosive, and occasionally has objectionable color, odor, and taste. The treatment used by public water-supply systems using river water is adequate at all times for removal of water-borne causes of disease. Attention is being concentrated on improving the quality of present supplies rather than developing new supplies from upstream tributaries. Present supplies are being improved by providing treatment facilities for disposal of wastes,, by reduction of acid mine drainage discharged into the streams, and by providing storage to augment low flows. The underground water resources are vitally important to the area. The use of ground water in the Pittsburgh area has doubled in the past two decades and in 1951 more ground water was used in Allegheny County than in any other county in

  13. Multiple bubbles in a Hele-Shaw cell

    Vasconcelos, G.L.

    1994-01-01

    A new class of exact solutions is reported for an infinite stream of identical groups of bubbles moving with a constant velocity U in a Hele-Shaw cell when surface tension is neglected. It is suggested that the existence of these solutions might explain some of the complex behavior observed in recent experiments on rising bubbles in a Hele-Shaw cell. Solutions for a finite number of bubbles in a channel are also obtained. In this case, it is shown that solutions with an arbitrary bubble velocity U>V, where V is the fluid velocity at infinity, can in general be obtained from a simple transformation of the solutions for U=2V

  14. Hyperbolic prisms and foams in Hele-Shaw cells

    Tufaile, A., E-mail: tufaile@usp.br [Soft Matter Laboratory, Escola de Artes, Ciencias e Humanidades, Universidade de Sao Paulo, 03828-000, Sao Paulo (Brazil); Tufaile, A.P.B. [Soft Matter Laboratory, Escola de Artes, Ciencias e Humanidades, Universidade de Sao Paulo, 03828-000, Sao Paulo (Brazil)

    2011-10-03

    The propagation of light in foams creates patterns which are generated due to the reflection and refraction of light. One of these patterns is observed by the formation of multiple mirror images inside liquid bridges in a layer of bubbles in a Hele-Shaw cell. We are presenting the existence of these patterns in foams and their relation with hyperbolic geometry and Sierpinski gaskets using the Poincare disk model. The images obtained from the experiment in foams are compared to the case of hyperbolic optical elements. -- Highlights: → The chaotic scattering of light in foams generating deltoid patterns is based on hyperbolic geometry. → The deltoid patterns are obtained through the Plateau borders in a Hele-Shaw cell. → The Plateau borders act like hyperbolic prism. → Some effects of the refraction and reflection of the light rays were studied using a hyperbolic prism.

  15. BikePGH's Pittsburgh Bike Map Geographic Data

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Files include data for bike lanes, protected bike lanes, trails, bike routes, shared lane markings, cautionary bike routes, and bridge data from the BikePGH...

  16. Pittsburgh American Community Survey Data 2015 - Household Types

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The data on relationship to householder were derived from answers to Question 2 in the 2015 American Community Survey (ACS), which was asked of all people in...

  17. EnviroAtlas - Pittsburgh, PA - Ecosystem Services by Block Group

    U.S. Environmental Protection Agency — This EnviroAtlas dataset presents environmental benefits of the urban forest in 1,089 block groups in Pittsburgh, Pennsylvania. Carbon attributes, temperature...

  18. Pittsburgh American Community Survey Census Data 2014 - Sex by Occupation

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Occupation describes the kind of work a person does on the job. Occupation data were derived from answers to questions 45 and 46 in the 2015 American Community...

  19. Stonehenge's avenue and ‘Bluestonehenge’

    Allen, M; Chan, B; Cleal, R; French, C; Marshall, P; Pollard, J; Pullen, R; Richards, C; Ruggles, C; Robinson, DW; Rylatt, J; Thomas, J; welham, K; Parker Peason, Mike

    2016-01-01

    Stonehenge is a site that continues to yield surprises. Excavation in 2009 added a new and unexpected feature: a smaller, dismantled stone circle on the banks of the River Avon, connected to Stonehenge itself by the Avenue. This new structure has been labelled 'Bluestonehenge' from the evidence that it once held a circle of bluestones that were later removed to Stonehenge. Investigation of the Avenue closer to Stonehenge revealed deep periglacial fissures within it. Their alignment on Stonehe...

  20. Sloshing in a Hele-Shaw cell: experiments and theory

    Viola , Francesco; Gallaire , Francois; Dollet , Benjamin

    2017-01-01

    International audience; The response of the free liquid surface in a Hele-Shaw cell subjected to a horizontal oscillation is investigated. We study the low-oscillation-amplitude regime and we show, by varying the fluid viscosity, ν, and the forcing frequency, ω, that the ratio between the Stokes viscous length, 2ν/ω, and the cell thickness greatly affects the amplitude and phase lag of the gravity waves. In particular, the sloshing system undergoes an under-damped/overdamped transition for su...

  1. Mixing foams and grains in Hele-Shaw cells

    Tufaile, A P B; Tufaile, A; Haddad, T A S, E-mail: tufaile@usp.b [Escola de Artes, Ciencias e Humanidades da Universidade de Sao Paulo, R. Arlindo Bettio, 1000, 03828-000, Sao Paulo (Brazil)

    2010-09-01

    We have observed some features of the coexistence of foams and granular materials in Hele-Shaw cells. The most part of the liquid and granular material stays at the bottom of the cell, with only a small quantity of the mixture resting on the froth. The fractal dimensions of the final states of the foams are close to the values obtained from the Random Apollonian Packing model. The disperse structure of the granular material affects the probability distribution of number of sides of the foam bubbles. The nearest neighbor distances between the peaks of the sand piles at the bottom of the cell are close to a lognormal distribution.

  2. POLLUTION PREVENTION OPPORTUNITY ASSESSMENT UNITED STATES ARMY CORPS OF ENGINEERS PITTSBURGH ENGINEER WAREHOUSE AND REPAIR STATION AND EMSWORTH LOCKS AND DAMS PITTSBURGH, PENNSYLVANIA

    This report summarizes work conducted at the United States Army Corps of Engineers (USACE) Pittsburgh Engineering Warehouse and Repair Station (PEWARS) and Emsworth Locks and Dams in Pittsburgh, Pennsylvania under the U.S. Environmental Protection Agency's (EPA's) Waste Reduction...

  3. Life support and euthanasia, a perspective on Shaw's new perspective.

    Busch, Jacob; Rodogno, Raffaele

    2011-02-01

    It has recently been suggested by Shaw (2007) that the distinction between voluntary active euthanasia, such as giving a patient a lethal overdose with the intention of ending that patient's life, and voluntary passive euthanasia, such as removing a patient from a ventilator, is much less obvious than is commonly acknowledged in the literature. This is argued by suggesting a new perspective that more accurately reflects the moral features of end-of-life situations. The argument is simply that if we consider the body of a mentally competent patient who wants to die, a kind of 'unwarranted' life support, then the distinction collapses. We argue that all Shaw has provided is a perspective that makes the conclusion that there is little distinction between voluntary active euthanasia and voluntary passive euthanasia only seemingly more palatable. In doing so he has yet to convince us that this perspective is superior to other perspectives and thus more accurately reflects the moral features of the situations pertaining to this issue.

  4. A Heat Vulnerability Index and Adaptation Solutions for Pittsburgh, Pennsylvania.

    Bradford, Kathryn; Abrahams, Leslie; Hegglin, Miriam; Klima, Kelly

    2015-10-06

    With increasing evidence of global warming, many cities have focused attention on response plans to address their populations' vulnerabilities. Despite expected increased frequency and intensity of heat waves, the health impacts of such events in urban areas can be minimized with careful policy and economic investments. We focus on Pittsburgh, Pennsylvania and ask two questions. First, what are the top factors contributing to heat vulnerability and how do these characteristics manifest geospatially throughout Pittsburgh? Second, assuming the City wishes to deploy additional cooling centers, what placement will optimally address the vulnerability of the at risk populations? We use national census data, ArcGIS geospatial modeling, and statistical analysis to determine a range of heat vulnerability indices and optimal cooling center placement. We find that while different studies use different data and statistical calculations, all methods tested locate additional cooling centers at the confluence of the three rivers (Downtown), the northeast side of Pittsburgh (Shadyside/Highland Park), and the southeast side of Pittsburgh (Squirrel Hill). This suggests that for Pittsburgh, a researcher could apply the same factor analysis procedure to compare data sets for different locations and times; factor analyses for heat vulnerability are more robust than previously thought.

  5. Microscopy Opening Up New Cancer Discovery Avenues

    Today’s high-powered microscopes are allowing researchers to study the fine details of individual cells and to peer into cells, opening up new avenues of discovery about the inner workings of cells, including the events that can cause healthy cells to tra

  6. Preparing for Local Adaptation: Understanding Flood Risk Perceptions in Pittsburgh

    Klima, K.; Wong-Parodi, G.

    2015-12-01

    The City of Pittsburgh experiences numerous floods every year. Aging and insufficient infrastructure contribute to flash floods and to over 20 billion gallons of combined sewer overflows annually, contaminating Pittsburgh's streets, basements, and waterways. Climate change is expected to further exacerbate this problem by causing more intense and more frequent extreme precipitation events in Western Pennsylvania. For a stormwater adaptation plan to be implemented effectively, the City will need informed public support. One way to achieve public understanding and support is through effective communication of the risks, benefits, and uncertainties of local flooding hazards and adaptation methods. In order to develop these communications effectively, the city and its partners will need to know what knowledge and attitudes the residents of Pittsburgh already hold about flood risks. Here we seek to (1) identify Pittsburgh residents' knowledge level, risk perception and attitudes towards flooding and storm water management, and (2) pre-test communications meant to inform and empower Pittsburghers about flood risks and adaptation strategies. We conduct a city-wide survey of 10,000 Pittsburgh renters and homeowners from four life situations: high risk, above poverty; high-risk, below poverty; low risk, above poverty; and low-risk, below poverty. Mixed media recruitment strategies (online and paper-based solicitations guided/organized by community organizations) assist in reaching all subpopulations. Preliminary results suggest participants know what stormwater runoff is, but have a weak understanding of how stormwater interacts with natural and built systems. Furthermore, although participants have a good understanding of the difference between green and gray infrastructure, this does not translate into a change in their willingness to pay for green infrastructure adaptation. This suggests additional communications about flood risks and adaptation strategies.

  7. Universality Results for Multi-phase Hele-Shaw Flows

    Daripa, Prabir

    2013-03-01

    Saffman-Taylor instability is a well known viscosity driven instability of an interface separating two immiscible fluids. We study linear stability of displacement processes in a Hele-Shaw cell involving an arbitrary number of immiscible fluid phases. This is a problem involving many interfaces. Universal stability results have been obtained for this multi-phase immiscible flow in the sense that the results hold for arbitrary number of interfaces. These stability results have been applied to design displacement processes that are considerably less unstable than the pure Saffman-Taylor case. In particular, we derive universal formula which gives specific values of the viscosities of the fluid layers corresponding to smallest unstable band. Other similar universal results will also be presented. The talk is based on the following paper. This work was supported by the Qatar National Research Fund (a member of The Qatar Foundation).

  8. Three dimensional vortices and interfaces in Hele-Shaw cells

    Pumir, A.

    1987-06-01

    A model of nonviscous flow, based on the Biot-Savart equations is used to examine the existence of singularities in three dimensional, incompressible, hydrodynamic equations. The results suggest a fairly simple physical mechanism, which could lead to the formation of singularities in the nonviscous case: two vortex tubes with opposite circulations pair up and stretch each other, until the radii of the vortex cores become extremely small, causing a divergence of the vorticity. The cases of a perfect and a slightly viscous fluid are considered. The results are unclear as to whether the vorticity of a slightly viscous fluid can become infinite or not, and whether singularities exist. The dynamics of hydrodynamic interfaces are also investigated. The propagation of bubbles in a slightly viscous fluid, in a Hele-Shaw cell are described [fr

  9. Faraday waves in a Hele-Shaw cell

    Li, Jing; Li, Xiaochen; Chen, Kaijie; Xie, Bin; Liao, Shijun

    2018-04-01

    We investigate Faraday waves in a Hele-Shaw cell via experimental, numerical, and theoretical studies. Inspired by the Kelvin-Helmholtz-Darcy theory, we develop the gap-averaged Navier-Stokes equations and end up with the stable standing waves with half frequency of the external forced vibration. To overcome the dependency of a numerical model on the experimental parameter of wave length, we take two-phase flow into consideration and a novel dispersion relation is derived. The numerical results compare well with our experimental data, which effectively validates our proposed mathematical model. Therefore, this model can produce robust solutions of Faraday wave patterns and resolve related physical phenomena, which demonstrates the practical importance of the present study.

  10. 75 FR 9867 - University of Pittsburgh, et al

    2010-03-04

    ... DEPARTMENT OF COMMERCE International Trade Administration University of Pittsburgh, et al.; Notice of Consolidated Decision on Applications for Duty-Free Entry of Electron Microscopes This is a decision consolidated pursuant to Section 6(c) of the Educational, Scientific, and Cultural Materials...

  11. Martin Luther King, Jr. East Busway in Pittsburgh, PA

    1987-10-01

    The Port Authority of Allegheny County (PAT), the primary public transit operator in Pittsburgh, PA, built an exclusive roadway for buses which opened for service in February 1983. The two-lane, 6.8-mile facility serves the eastern suburbs via a righ...

  12. Perspectives on Art Therapy: The Proceedings of the Pittsburgh Conference on Art Therapy (2nd, Pittsburgh, Pennsylvania, May 20, 1977).

    Roth, Ellen A., Ed.; Rubin, Judith A., Ed.

    The proceedings of the 2nd annual Pittsburgh Conference on Art Therapy (with handicapped persons) consists of 44 items including full length papers, summaries of previously published papers, descriptions of workshops, and a limited number of abstracts (submitted by those who chose not to present a paper or workshop description). The papers are…

  13. Avenues of Rethinking CSR in development

    Azizi, Sameer Ahmad

    2015-01-01

    ’. The developmental implication is based on the governance structures triggering CSR in each context. We need to differentiate between strong and weak states and understand the ways that (lack of) states can influence CSR in developing countries. "Responsible business practices" are explored as useful among......The chapter addresses flaws of the CSR literature and seeks to rethink the concept in relation to developing countries. Two avenues for rethinking CSR in developing countries are outlined; a) a governance approach, and b) an application of the term ‘responsible business practices...

  14. Bettis Atomic Power Laboratory. Bettis-Pittsburgh Site environmental summary report

    None

    2000-01-01

    This summary report provides a description of the nature and environmental aspects of work and facilities at the Bettis-Pittsburgh site, an historical perspective of Bettis-Pittsburgh operations that is not provided by the annual reports, and background information pertinent to understanding the environmental aspects of Bettis-Pittsburgh operations

  15. 77 FR 34297 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Pittsburgh-Beaver...

    2012-06-11

    ... Promulgation of Air Quality Implementation Plans; Pennsylvania; Pittsburgh-Beaver Valley Nonattainment Area... Pittsburgh-Beaver Valley fine particulate matter (PM 2.5 ) nonattainment area (hereafter referred to as ``the... designations process. The Pittsburgh Area is comprised of the counties of Beaver, Butler, Washington, and...

  16. The upper pennsylvanian pittsburgh coal bed: Resources and mine models

    Watson, W.D.; Ruppert, L.F.; Tewalt, S.J.; Bragg, L.J.

    2001-01-01

    The U.S. Geological Survey recently completed a digital coal resource assessment model of the Upper Pennsylvanian Pittsburgh coal bed, which indicates that after subtracting minedout coal, 16 billion short tons (14 billion tonnes) remain of the original 34 billion short tons (31 billion tonnes) of coal. When technical, environmental, and social restrictions are applied to the remaining Pittsburgh coal model, only 12 billion short tons (11 billion tonnes) are available for mining. Our assessment models estimate that up to 0.61 billion short tons (0.55 billion tonnes), 2.7 billion short tons (2.4 billion tonnes), and 8.5 billion short tons (7.7 billion tonnes) could be available for surface mining, continuous mining, and longwall mining, respectively. This analysis is an example of a second-generation regional coal availability study designed to model recoverability characteristics for all the major coal beds in the United States. ?? 2001 International Association for Mathematical Geology.

  17. Elastic fingering in rotating Hele-Shaw flows

    Carvalho, Gabriel D.

    2014-05-21

    The centrifugally driven viscous fingering problem arises when two immiscible fluids of different densities flow in a rotating Hele-Shaw cell. In this conventional setting an interplay between capillary and centrifugal forces makes the fluid-fluid interface unstable, leading to the formation of fingered structures that compete dynamically and reach different lengths. In this context, it is known that finger competition is very sensitive to changes in the viscosity contrast between the fluids. We study a variant of such a rotating flow problem where the fluids react and produce a gellike phase at their separating boundary. This interface is assumed to be elastic, presenting a curvature-dependent bending rigidity. A perturbative weakly nonlinear approach is used to investigate how the elastic nature of the interface affects finger competition events. Our results unveil a very different dynamic scenario, in which finger length variability is not regulated by the viscosity contrast, but rather determined by two controlling quantities: a characteristic radius and a rigidity fraction parameter. By properly tuning these quantities one can describe a whole range of finger competition behaviors even if the viscosity contrast is kept unchanged. © 2014 American Physical Society.

  18. Droplet formation in Hele-Shaw T-junction.

    Ricouvier, Joshua; Yazhgur, Pavel; Leshansky, Alexander; Tabeling, Patrick; Microflusa Team

    The development of digital microfluidics has attracted considerable interest towards generation of highly monodisperse microdroplets. T-junction has become an essential element of most of microfluidic chips. Despite its importance, theoretical analysis of droplet formation at T-junction is still incomplete due to complexity of physics involved. We focused on droplet generation at the Hele-Shaw T-junction. The effect of various experimental parameters, such as channel geometry, flow rates, surface tension and fluid viscosities, was thoroughly investigated. Our results show that the experimental system exhibits three distinct regimes (squeezing, dripping and jetting regimes) and point out the effect of confinement on the transitions. We demonstrate that the size of the ''plug'' droplet depends not only on the flow rate ratio (as described in the literature), but also on the capillary number and the channel cross-section aspect ratio. Quasi-2D flow equations allow us to perform numerical simulations and to compare them with experimental results. The Microflusa project receives funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. 664823.

  19. Elastic fingering in rotating Hele-Shaw flows

    Carvalho, Gabriel D.; Gadê lha, Hermes; Miranda, José A.

    2014-01-01

    The centrifugally driven viscous fingering problem arises when two immiscible fluids of different densities flow in a rotating Hele-Shaw cell. In this conventional setting an interplay between capillary and centrifugal forces makes the fluid-fluid interface unstable, leading to the formation of fingered structures that compete dynamically and reach different lengths. In this context, it is known that finger competition is very sensitive to changes in the viscosity contrast between the fluids. We study a variant of such a rotating flow problem where the fluids react and produce a gellike phase at their separating boundary. This interface is assumed to be elastic, presenting a curvature-dependent bending rigidity. A perturbative weakly nonlinear approach is used to investigate how the elastic nature of the interface affects finger competition events. Our results unveil a very different dynamic scenario, in which finger length variability is not regulated by the viscosity contrast, but rather determined by two controlling quantities: a characteristic radius and a rigidity fraction parameter. By properly tuning these quantities one can describe a whole range of finger competition behaviors even if the viscosity contrast is kept unchanged. © 2014 American Physical Society.

  20. Preparing for local adaptation: Understanding flood risk perceptions in Pittsburgh

    Wong-Parodi, G.; Klima, K.

    2016-12-01

    In cities such as Pittsburgh, aging and insufficient infrastructure contributes to flashfloods and numerous combined sewer overflows annually, contaminating streets, basements and waterways. Climate change is expected to further exacerbate this problem by causing more intense and more frequent extreme events in Western Pennsylvania. For a storm water adaptation plan to be implemented successfully, the City of Pittsburgh will need informed public support. One way to achieve public understanding and support is through effective communication of the risks, benefits, and uncertainties of local flooding hazards and adaptation methods. In order to develop risk communications effectively, the City and its partners will need to know what knowledge and attitudes the residents of Pittsburgh already hold about flood risks. To that end we surveyed 1,376 Pittsburgh residents on a variety of flood risk topics through an online or paper survey in Fall 2015. On balance, residents were relatively knowledgeable about storm water and see the City's current infrastructure as being inadequate to meet future risk. Moreover, they see the risk of runoff events as increasing and especially among those who live in hazardous flood areas. Residents expressed interest in having a dedicated fund to deal with runoff events. Among those queried about their willingness-to-pay, those asked to pay $15 were most interested in a dedicated fund and for green infrastructure (as opposed to gray infrastructure) in particular. Finally, while most residents favored green infrastructure in terms of its attractiveness and perceived affects on mitigating climate change many did not see it as effective at addressing flooding as gray infrastructure. We found people understand the risk and are open to doing something about it. However, more guidance and information on appropriate ways to adapt locally in terms that make sense to residents could enhance informed support for adaptation measures.

  1. Bubble propagation in Hele-Shaw channels with centred constrictions

    Franco-Gómez, Andrés; Thompson, Alice B.; Hazel, Andrew L.; Juel, Anne

    2018-04-01

    We study the propagation of finite bubbles in a Hele-Shaw channel, where a centred occlusion (termed a rail) is introduced to provide a small axially uniform depth constriction. For bubbles wide enough to span the channel, the system’s behaviour is similar to that of semi-infinite fingers and a symmetric static solution is stable. Here, we focus on smaller bubbles, in which case the symmetric static solution is unstable and the static bubble is displaced towards one of the deeper regions of the channel on either side of the rail. Using a combination of experiments and numerical simulations of a depth-averaged model, we show that a bubble propagating axially due to a small imposed flow rate can be stabilised in a steady symmetric mode centred on the rail through a subtle interaction between stabilising viscous forces and destabilising surface tension forces. However, for sufficiently large capillary numbers Ca, the ratio of viscous to surface tension forces, viscous forces in turn become destabilising thus returning the bubble to an off-centred propagation regime. With decreasing bubble size, the range of Ca for which steady centred propagation is stable decreases, and eventually vanishes through the coalescence of two supercritical pitchfork bifurcations. The depth-averaged model is found to accurately predict all the steady modes of propagation observed experimentally, and provides a comprehensive picture of the underlying steady bifurcation structure. However, for sufficiently large imposed flow rates, we find that initially centred bubbles do not converge onto a steady mode of propagation. Instead they transiently explore weakly unstable steady modes, an evolution which results in their break-up and eventual settling into a steady propagating state of changed topology.

  2. Avenues for crowd science in Hydrology.

    Koch, Julian; Stisen, Simon

    2016-04-01

    Crowd science describes research that is conducted with the participation of the general public (the crowd) and gives the opportunity to involve the crowd in research design, data collection and analysis. In various fields, scientists have already drawn on underused human resources to advance research at low cost, with high transparency and large acceptance of the public due to the bottom up structure and the participatory process. Within the hydrological sciences, crowd research has quite recently become more established in the form of crowd observatories to generate hydrological data on water quality, precipitation or river flow. These innovative observatories complement more traditional ways of monitoring hydrological data and strengthen a community-based environmental decision making. However, the full potential of crowd science lies in internet based participation of the crowd and it is not yet fully exploited in the field of Hydrology. New avenues that are not primarily based on the outsourcing of labor, but instead capitalize the full potential of human capabilities have to emerge. In multiple realms of solving complex problems, like image detection, optimization tasks, narrowing of possible solutions, humans still remain more effective than computer algorithms. The most successful online crowd science projects Foldit and Galaxy Zoo have proven that the collective of tens of thousands users could clearly outperform traditional computer based science approaches. Our study takes advantage of the well trained human perception to conduct a spatial sensitivity analysis of land-surface variables of a distributed hydrological model to identify the most sensitive spatial inputs. True spatial performance metrics, that quantitatively compare patterns, are not trivial to choose and their applicability is often not universal. On the other hand humans can quickly integrate spatial information at various scales and are therefore a trusted competence. We selected

  3. Rotating Hele-Shaw cell with a time-dependent angular velocity

    Anjos, Pedro H. A.; Alvarez, Victor M. M.; Dias, Eduardo O.; Miranda, José A.

    2017-12-01

    Despite the large number of existing studies of viscous flows in rotating Hele-Shaw cells, most investigations analyze rotational motion with a constant angular velocity, under vanishing Reynolds number conditions in which inertial effects can be neglected. In this work, we examine the linear and weakly nonlinear dynamics of the interface between two immiscible fluids in a rotating Hele-Shaw cell, considering the action of a time-dependent angular velocity, and taking into account the contribution of inertia. By using a generalized Darcy's law, we derive a second-order mode-coupling equation which describes the time evolution of the interfacial perturbation amplitudes. For arbitrary values of viscosity and density ratios, and for a range of values of a rotational Reynolds number, we investigate how the time-dependent angular velocity and inertia affect the important finger competition events that traditionally arise in rotating Hele-Shaw flows.

  4. 77 FR 5781 - Record of Decision for the Air Space Training Initiative Shaw Air Force Base, South Carolina...

    2012-02-06

    ... DEPARTMENT OF DEFENSE Department of the Air Force Record of Decision for the Air Space Training Initiative Shaw Air Force Base, South Carolina Final Environmental Impact Statement ACTION: Notice of... signed the ROD for the Airspace Training Initiative Shaw Air Force Base, South Carolina Final...

  5. Self-Expression or Teacher Influence: The Shaw System of Finger-Painting.

    Stankiewicz, Mary Ann

    1984-01-01

    Finger painting is often regarded as the epitome of free expression for children. However, a careful review of the history of Ruth Shaw's finger-painting system reveals that it was dominated by specific techniques and stylistic conventions taught without a critical understanding of art history or appreciation. (IS)

  6. Computer simulation of viscous fingering in a lifting Hele-Shaw cell

    We simulate viscous fingering generated by separating two plates with a constant force, in a lifting Hele-Shaw cell. Variation in the patterns for different fluid viscosity and lifting force is studied. Viscous fingering is strongly affected by anisotropy. We report a computer simulation study of fingering patterns, where circular or ...

  7. Hele-Shaw beach creation by breaking waves: a mathematics-inspired experiment

    Thornton, Anthony Richard; van der Horn, Avraham/Bram; van der Horn, Avraham J.; Gagarina, Elena; Zweers, Wout; van der Meer, Roger M.; Bokhove, Onno

    2014-01-01

    Fundamentals of nonlinear wave-particle interactions are studied experimentally in a Hele-Shaw configuration with wave breaking and a dynamic bed. To design this configuration, we determine, mathematically, the gap width which allows inertial flows to survive the viscous damping due to the side

  8. Experimental particle physics at the University of Pittsburgh

    Engels, E. Jr.; Shepard, P.F.; Thompson, J.A.

    1994-05-01

    Task A involves the study of kaon decays. The overall physics focus of the current work is rare and semi-rare decays of the φ and the short-lived kaon, with an emphasis on those aspects needed in preparation for the proposed Φ-factory measurements of CPT violation. Another aspect of the rare kaon decay work is E865 at BNL, a search for K + yields π + μ + e - , a lepton number violating process. Pittsburgh's E865 responsibilities are the design and construction of the Cerenkov counters. The major goals of task B are as follows: (1) the analysis of the E706 (direct photon production) data taken during the 1987--1988 and 1990--1991 target runs at Fermilab and (2) the continuation of work within SVXII group of the CDF collaboration. The CDF program involves a dedicated effort towards the design of the silicon vertex detector upgrade, SVXII

  9. Blood-brain transfer of Pittsburgh compound B in humans

    Gjedde, Albert; Aanerud, Joel; Braendgaard, Hans

    2013-01-01

    -brain barrier is held to be high but the permeability-surface area product and extraction fractions in patients or healthy volunteers are not known. We used PET to determine the clearance associated with the unidrectional blood-brain transfer of [(11)C]PiB and the corresponding cerebral blood flow rates...... with the observation that numerically, but insignificantly, unidirectional blood-brain clearances are lower and extraction fractions higher in the patients. The evidence of unchanged permeability-surface area products in the patients implies that blood flow changes can be deduced from the unidirectional blood......In the labeled form, the Pittsburgh compound B (2-(4'-{N-methyl-[(11)C]}methyl-aminophenyl)-6-hydroxy-benzothiazole, [(11)C]PiB), is used as a biomarker for positron emission tomography (PET) of brain β-amyloid deposition in Alzheimer's disease (AD). The permeability of [(11)C]PiB in the blood...

  10. Pneumonia caused by Pittsburgh pneumonia agent: radiologic manifestations

    Muder, R.R.; Reddy, S.C.; Yu, V.L.; Kroboth, F.J.

    1984-01-01

    Using an objective scoring system, chest radiographs were reviewed in 23 cases of pneumonia due to the Pittsburgh pneumonia agent (PPA, Tatlockia micdadei, Legionella micdadei), including six cases of pneumonia with simultaneous isolation of PPA and L pneumophila (Legionnaires' disease). Infiltrates were typically segmental to lobar; nodular infiltrates were noted in three cases. Spread to additional lobes after presentation occurred in four of 17 PPA infections. Pneumonia caused by both PPA and L pneumophila was unusually severe, with involvement of all lobes occurring in four of six cases, compared with one of 17 cases of PPA infection (p>0.02). Radiographic severity did not correlate with underlying disease, immune status, or outcome. The majority of patients receiving erythromycin demonstrated objective radiologic improvement. In a patients, population that included nonimmunosuppressed patient, nodule formation and rapid radiologic progression were not found to be characteristic of PPA pneumonia

  11. 77 FR 62147 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Pittsburgh-Beaver...

    2012-10-12

    ... Promulgation of Air Quality Implementation Plans; Pennsylvania; Pittsburgh-Beaver Valley Nonattainment Area... (EPA). ACTION: Final rule. SUMMARY: EPA is making two determinations regarding the Pittsburgh- Beaver... 12.7 Collocated Armstrong 42-005-0001 Kittaning......... 11.0 13.2 12.1 12.1 Incomplete \\2\\ Beaver 42...

  12. Prediction of Instability for Miscible Displacements in a Hele-Shaw Cell Prévision de l'instabilité pour des déplacements miscibles dans une cellule Hele-Shaw

    Coskuner G.

    2006-11-01

    Full Text Available A universal dimensionless scaling group and its critical value at the onset of instability for a miscible displacement in a Hele-Shaw cell is derived. The derivation is based on a variational technique and it is capable of considering, for the first time, the effect of the length of a Hele-Shaw cell on the criterion for the onset of instability. The theory is verified by comparing it with forty-four Hele-Shaw cell experiments. On calcule un groupe universel sans dimension de mise à l'échelle et sa valeur critique au départ de l'instabilité dans un déplacement miscible dans une cellule Hele-Shaw. Ce calcul est basé sur une technique variationnelle et permet, pour la première fois, de prendre en compte l'effet de la longueur d'une cellule Hele-Shaw sur le critère d'apparition d'instabilité. La théorie est vérifiée en la comparant avec des expériences réalisées avec quarante-quatre cellules Hele-Shaw.

  13. On a Hele-Shaw flow with a time-dependent gap in the presence of surface tension

    Savina, T V; Nepomnyashchy, A A

    2015-01-01

    The introduction of surface tension into a Hele-Shaw problem makes it more realistic from the physical viewpoint, but more difficult from the mathematical viewpoint. In this paper we discuss a Hele-Shaw flow with a time-dependent gap taking into account the surface tension of the free boundary. We use the Schwarz function method to find asymptotic solutions for the interior problem in the case when the initial shape of the droplet is a weakly distorted circle. (paper)

  14. Determining the number of fingers in the lifting Hele-Shaw problem

    Miranda, Jose; Dias, Eduardo

    2013-11-01

    The lifting Hele-Shaw cell flow is a variation of the celebrated radial viscous fingering problem for which the upper cell plate is lifted uniformly at a specified rate. This procedure causes the formation of intricate interfacial patterns. Most theoretical studies determine the total number of emerging fingers by maximizing the linear growth rate, but this generates discrepancies between theory and experiments. In this work, we tackle the number of fingers selection problem in the lifting Hele-Shaw cell by employing the recently proposed maximum-amplitude criterion. Our linear stability analysis accounts for the action of capillary, viscous normal stresses, and wetting effects, as well as the cell confinement. The comparison of our results with very precise laboratory measurements for the total number of fingers shows a significantly improved agreement between theoretical predictions and experimental data. We thank CNPq (Brazilian Sponsor) for financial support.

  15. Genealogy of John and Charles Bell: their relationship with the children of Charles Shaw of Ayr.

    Kaufman, M

    2005-11-01

    The Reverend William Bell had six children who survived infancy. Two of his sons entered the legal profession and two other sons became distinguished anatomists and surgeons--John Bell, said for 20 years to have been the leading operating surgeon in Britain and throughout the world--and Sir Charles Bell, possibly the most distinguished anatomist and physiologist of his day. Information is not known about the fifth son or their sister. Charles Shaw, a lawyer of Ayr, had four sons and two daughters who survived infancy. Two of his sons, John and Alexander, became anatomists and later surgeons at the Middlesex Hospital, and both worked closely with Charles Bell at the Great Windmill Street School of Anatomy. His third son entered the law and his fourth son became a distinguished soldier. The two daughters of Charles Shaw married into the Bell family: Barbara married George Joseph Bell and Marion married Mr (later Sir) Charles Bell.

  16. Environmental Assessment for Wing Infrastructure Development Outlook (WINDO) Plan Shaw Air Force Base, South Carolina

    2004-10-01

    officially established on August 30, 1941 and was named after 1st Lt. Ervin D. Shaw, a Sumter County resident who was killed in action during World War I...Examples of the animal species likely to occur within this community include the cottontail, mockingbird , American robin, and crow. At the Poinsett...include the white-tailed deer, red fox, raccoon, opossum, striped skunk, cottontail, meadowlark, mockingbird , American kestrel, fence lizard, and

  17. A Special Class of Univalent Functions in Hele-Shaw Flow Problems

    Paula Curt

    2011-01-01

    Full Text Available We study the time evolution of the free boundary of a viscous fluid for planar flows in Hele-Shaw cells under injection. Applying methods from the theory of univalent functions, we prove the invariance in time of Φ-likeness property (a geometric property which includes starlikeness and spiral-likeness for two basic cases: the inner problem and the outer problem. We study both zero and nonzero surface tension models. Certain particular cases are also presented.

  18. Henri Bergson y George Bernard Shaw: hábito, vida, muerte

    Álvaro Cortina Urdampilleta

    2015-01-01

    Full Text Available Este artículo indaga en algunos aspectos de la antropología filosófica expuesta en la obra del francés Henri Bergson. Para ello, nos serviremos de la confrontación de su doctrina original con la de un bergsoniano sui generis, el intelectual y dramaturgo irlandés George Bernard Shaw. El Prefacio. A medio siglo infiel, de Shaw, incluido en su obra más ambiciosa, Vuelta a Matusalén. Un Pentateuco Metabiológico, de 1921, será el texto base con el que haremos dialogar a Bergson con este periférico bergsonismo. Tomaremos como hilo conductor la teoría sobre el hábito, en el contexto de la metafísica de la evolución de los seres orgánicos, y lo llevaremos hasta el concepto límite, que parece conciliar ambas posturas: la idea de muerte superable. Ni en Bergson ni en Shaw los hábitos (la Cultura forman parte integral de la esencia del hombre, y la muerte (cuestión en la que Bergson es mucho más elusivo juega en ellos un rol anfibio, entre Cultura y Naturaleza.

  19. EnviroAtlas - Pittsburgh, PA - Meter-Scale Urban Land Cover (MULC) Data (2010)

    U.S. Environmental Protection Agency — The EnviroAtlas Pittsburgh, PA Meter-Scale Urban Land Cover (MULC) data was generated from United States Department of Agriculture (USDA) National Agricultural...

  20. EnviroAtlas - Pittsburgh, PA - BenMAP Results by Block Group

    U.S. Environmental Protection Agency — This EnviroAtlas dataset demonstrates the effect of changes in pollution concentration on local populations in 1,089 block groups in Pittsburgh, PA. The US EPA's...

  1. Experimental particle physics at the University of Pittsburgh: Progress report, April 1, 1988--March 31, 1989

    Cleland, W.E.; Coon, D.D.; Engels, E. Jr.; Shepard, P.F.; Thompson, J.A.

    1988-12-01

    This report discusses the experimental work in particle physics at the University of Pittsburgh. Topics discussed are: lepton production at the CERN SPS; direct photon production at the Tevatron; and search for fractional charge particles in semiconductors

  2. Smoky ol' town: the significance of Pittsburgh in U.S. air pollution history

    James Longhurst [Muskingum College, New Concord, OH (United States)

    2007-06-15

    Pittsburgh came to be - and came to be dirtybecause of location, location, and location. Two navigable rivers met in the middle of a forest, and combined to form a third river. This was an irresistible meeting point for settlement, trade, and industry. It was an added bonus that this meeting point was at the center of the 'Pittsburgh seam' of coal. While the natural advantages of geography and geology initiated development, Pittsburgh's growth soon attracted man-made transportation networks to import resources from its hinterland and spread finished materials through the Midwest. As the city boomed into an industrial metropolis - the Iron City, the Steel City - through the late 19th and early 20th centuries, the smoke only became worse, and Pittsburgh became known, nationally and even internationally, for its dirt, grime, and filth. For many of the city's workers and businessmen, smoke was a sign of progress and economic success. From small-scale iron production, to the process of refining coal into 'coke,' to the Bessemer steel process, to J.P. Morgan and Andrew Carnegie's creation of the vertically-integrated U.S. Steel corporation, to the pioneering use of 'byproduct' coke ovens, Pittsburgh was home to successive technologies for transforming raw materials into finished or refined goods. Pittsburgh is both singular and representative; its story is at the forefront of pollution history, but the forces, trends, and events the city witnessed were the same in many cities across the nation. So while it is true that A&WMA's headquarters are in Pittsburgh for a reason, it is also true that its membership is spread across the nation and the world. That membership will most likely find something in these four themes from Pittsburgh's history that is representative of their own study. 7 refs., 3 photos.

  3. Tiger Team Assessment of the Pittsburgh Energy Technology Center, [August 19--September 13, 1991

    1991-09-01

    This report documents the results of the Department of Energy (DOE) Tiger Team Assessment conducted at Pittsburgh Energy Technology Center (PETC) near Pittsburgh, Pennsylvania, between August 19 and September 13, 1991. A team comprised of professionals from the Department, its contractors, and consultants conducted the assessment. The purpose of the assessment was to provide the Secretary of Energy the status of environment, safety, and health (ES ampersand H) programs at PETC. A management assessment was performed

  4. Structural validity of the Pittsburgh Sleep Quality Index in Chinese undergraduate students: A confirmatory factor analysis

    Suran Guo; chang liu; wenmei sun; siwei wu

    2016-01-01

    The purpose of this study was to examine the structural validity of the Pittsburgh Sleep Quality Index (PSQI) in Chinese undergraduate students. A cross-sectional questionnaire survey with 631 Chinese undergraduate students was conducted, and the questionnaire package included a measure of demographic characteristics, Pittsburgh Sleep Quality Index (PSQI), Chinese editions of Center for Epidemiologic Studies-Depression, State- Trait Anxiety Inventory, Rumination Response Scale, and Perceived ...

  5. Robert R. Shaw, MD: thoracic surgical hero, Afghanistan medical pioneer, champion for the patient, never a surgical society president.

    Urschel, Harold C; Urschel, Betsey Bradley

    2012-06-01

    Dr Robert R. Shaw arrived in Dallas to practice Thoracic Surgery in 1937, as John Alexander's 7th Thoracic Surgical Resident from Michigan University Medical Center. Dr Shaw's modus operandi was, "You can accomplish almost anything, if you don't care who gets the credit." He was a remarkable individual who cared the most about the patient and very little about getting credit for himself. From 1937 to 1970, Dr Shaw established one of the largest lung cancer surgical centers in the world in Dallas, Texas. It was larger than M.D. Anderson and Memorial Sloan-Kettering Hospitals put together regarding the surgical treatment of lung cancer patients. To accomplish this, he had the help of Dr Donald L. Paulson, who trained at the Mayo Clinic and served as Chief of Thoracic Surgery at Brook Army Hospital during the Second World War. Following the War, because of his love for Texas, he ended up as a partner of Dr Shaw in Dallas. Together, they pursued the development of this very large surgical lung cancer center. Dr Shaw and his wife Ruth went to Afghanistan with Medico multiple times to teach men modern cardiac and thoracic surgery. They also served as consultants on Medico's Ship of Hope in Africa. Dr Shaw initiated multiple new operations including: 1) resection of Pancoast's cancer of the lung after preoperative irradiation; 2) upper lobe of the lung bronchoplasty, reattaching (and saving) the lower lobe to prevent the "disabling" pneumonectomy; and 3) resections of pulmonary mucoid impaction of the lung in asthmatics. Because of his humility and giving "the credit to others," Dr Shaw was never President of a major medical or surgical association. Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  6. An assembly of steadily translating bubbles in a Hele–Shaw channel

    Crowdy, Darren

    2009-01-01

    This paper presents new solutions for any finite number of bubbles steadily translating along a Hele–Shaw channel. This constitutes a nonlinear free boundary problem. The solutions can be written down explicitly in terms of a special transcendental function called the Schottky–Klein prime function. This work generalizes the exact solutions for a single bubble in a channel found by Tanveer (1987 Phys. Fluids 30 651–8) as well as the solutions for streams of bubbles aligned along the channel centreline due to Vasconcelos (1994 Phys. Rev. E 50 R3306–9)

  7. Non-Newtonian Hele-Shaw Flow and the Saffman-Taylor Instability

    Kondic, L.; Shelley, M.J.; Palffy-Muhoray, P.

    1998-01-01

    We explore the Saffman-Taylor instability of a gas bubble expanding into a shear thinning liquid in a radial Hele-Shaw cell. Using Darcy close-quote s law generalized for non-Newtonian fluids, we perform simulations of the full dynamical problem. The simulations show that shear thinning significantly influences the developing interfacial patterns. Shear thinning can suppress tip splitting, and produce fingers which oscillate during growth and shed side branches. Emergent length scales show reasonable agreement with a general linear stability analysis. copyright 1998 The American Physical Society

  8. New archeointensity results from the reconstructed ancient kiln by the Tsunakawa-Shaw method

    Yamamoto, Y.; Hatakeyama, T.; Kitahara, Y.; Saito, T.

    2017-12-01

    Yamamoto et al. (2015) reported that baked clay samples from the floor of a reconstructed ancient kiln provided a reliable Tsunakawa-Shaw (LTD-DHT Shaw) archeointensity (AI) estimate of 47.3 +/- 2.2 microT which is fairly consistent with the in situ geomagnetic field of 46.4 microT at the time of the reconstruction. The reconstruction was conducted to reproduce an excavated kiln of the seventh century in Japan and Sue-type potteries of contemporary style were also fired (Nakajima et al., 1974). Two of the potteries with reddish color were recently subjected to the Tsunakawa-Shaw archeointensity determinations, resulting in reliable AI estimates of 45.4 +/- 2.3 (N=6) and 48.2 +/- 2.7 microT (N=15) when specimens were heated in air in laboratory (Yamamoto et al., 2017 JpGU-AGU Joint Meeting). We have had another opportunity to take samples from a new reconstructed ancient kiln in Japan which was fired in autumn 2016. The samples were two Sue-type potteries with grayish color (bowl-type and plate-type) and some blocks collected from inner wall of the kiln body. They were cut into mini specimens and then subjected to the Tsunakawa-Shaw experiment. Heating in laboratory was done either in air or vacuum.For the bowl-type pottery, AIs of 46.9 +/- 2.8 (N=6, air) and 45.3 +/- 2.3 microT (N=6, vacuum) are obtained. They are indistinguishable each other and consistent with the IGRF field of 47.4 microT at the reconstructed location in 2016. For the plate-type pottery, AIs result in 41.8 +/- 1.3 (N=4, air) and 43.9 +/- 3.9 microT (N=4, vacuum). They are also indistinguishable each other but the former AI is slightly lower than the IGRF field.For the inner wall, AIs of 45.0 (N=1, air) and 46.8 microT (N=1, vacuum) are obtained from a right-side wall, and those of 45.5 +/- 2.5 (N=2, air) and 47.7 +/- 3.0 microT (N=2, vacuum) are observed from a left-side wall. They are all indistinguishable and consistent with the IGRF field.

  9. Premixed combustion of coconut oil in a hele-shaw cell

    Hadi Saroso

    2014-12-01

    Full Text Available Coconut oil combustion characteristic is observed experimentally by evaporating oil in the boiler then mix it with air before being burned at various equivalence ratios in the Hele-shaw cell. The result shows that, coconut oil tends to break into glycerol and fatty acid due to hydrolysis reaction producing the flame propagation, where the fatty acid flame propagates first then glycerol flame. Micro-explosion occurs when moisture from fatty acid combustion is absorbed by glycerol and higher heating due to higher flame speed produces more micro-explosion.

  10. Analisis Isi Lambung Ikan Senangin (Eleutheronema tetradactylum Shaw di Perairan Dumai

    Titrawani Titrawani

    2016-03-01

    Full Text Available The research about stomach content analysis of thraedfin fish (Eleutheronema tetradactylum Shaw “senangin fish” in Dumai aquatic was taken out on July until Maret 2011. The research aimed to know the kind of senangin fish’s food include main food, supplement food and additional food. The used analysis based on Natarjan and Jingran in Effendi (1979, by analysis index of preponderance (Higher Part Index. Based on them main food of senangin fish are  Crustacea,  Engraulidae and animal debric.

  11. Bubble extinction in Hele-Shaw flow with surface tension and kinetic undercooling regularization

    Dallaston, Michael C; McCue, Scott W

    2013-01-01

    We perform an analytic and numerical study of an inviscid contracting bubble in a two-dimensional Hele-Shaw cell, where the effects of both surface tension and kinetic undercooling on the moving bubble boundary are not neglected. In contrast to expanding bubbles, in which both boundary effects regularize the ill-posedness arising from the viscous (Saffman–Taylor) instability, we show that in contracting bubbles the two boundary effects are in competition, with surface tension stabilizing the boundary, and kinetic undercooling destabilizing it. This competition leads to interesting bifurcation behaviour in the asymptotic shape of the bubble in the limit it approaches extinction. In this limit, the boundary may tend to become either circular, or approach a line or ‘slit’ of zero thickness, depending on the initial condition and the value of a nondimensional surface tension parameter. We show that over a critical range of surface tension values, both these asymptotic shapes are stable. In this regime there exists a third, unstable branch of limiting self-similar bubble shapes, with an asymptotic aspect ratio (dependent on the surface tension) between zero and one. We support our asymptotic analysis with a numerical scheme that utilizes the applicability of complex variable theory to Hele-Shaw flow. (paper)

  12. Contracting bubbles in Hele-Shaw cells with a power-law fluid

    McCue, Scott W; King, John R

    2011-01-01

    The problem of bubble contraction in a Hele-Shaw cell is studied for the case in which the surrounding fluid is of power-law type. A small perturbation of the radially symmetric problem is first considered, focussing on the behaviour just before the bubble vanishes, it being found that for shear-thinning fluids the radially symmetric solution is stable, while for shear-thickening fluids the aspect ratio of the bubble boundary increases. The borderline (Newtonian) case considered previously is neutrally stable, the bubble boundary becoming elliptic in shape with the eccentricity of the ellipse depending on the initial data. Further light is shed on the bubble contraction problem by considering a long thin Hele-Shaw cell: for early times the leading-order behaviour is one-dimensional in this limit; however, as the bubble contracts its evolution is ultimately determined by the solution of a Wiener–Hopf problem, the transition between the long thin limit and the extinction limit in which the bubble vanishes being described by what is in effect a similarity solution of the second kind. This same solution describes the generic (slit-like) extinction behaviour for shear-thickening fluids, the interface profiles that generalize the ellipses that characterize the Newtonian case being constructed by the Wiener–Hopf calculation

  13. Gas driven displacement in a Hele-Shaw cell with chemical reaction

    White, Andrew; Ward, Thomas

    2011-11-01

    Injecting a less viscous fluid into a more viscous fluid produces instabilities in the form of fingering which grow radially from the less viscous injection point (Saffman & Taylor, Proc. R. Soc. Lon. A, 1958). For two non-reacting fluids in a radial Hele-Shaw cell the ability of the gas phase to penetrate the liquid phase is largely dependent on the gap height, liquid viscosity and gas pressure. In contrast combining two reactive fluids such as aqueous calcium hydroxide and carbon dioxide, which form a precipitate, presents a more complex but technically relevant system. As the two species react calcium carbonate precipitates and increases the aqueous phase visocosity. This change in viscosity may have a significant impact on how the gas phase penetrates the liquid phase. Experimental are performed in a radial Hele-Shaw cell with gap heights O(10-100) microns by loading a single drop of aqueous calcium hydroxide and injecting carbon dioxide into the drop. The calcium hydroxide concentration, carbon dioxide pressure and gap height are varied and images of the gas penetration are analyzed to determine residual film thickness and bursting times.

  14. Narsisisme dan Kompleks Oedipus yang Tergambar dalam Pygmalion, Karya George Bernard Shaw

    Essy Syam

    2017-06-01

    Full Text Available Abstract This writing analyzes narcisism and oedipuis complex as refelcted in a literary work entitles “pygmalion” written by George Bernard Shaw. Thus, the objective of this analysis is to show and to analyze how narcisism and Oedipus complex are suffered from the protagonist of this work. To reach that objective, this analysis applies psychoanalitical analysis  to demonstrate the mental condition of the main character. Related to that idea, this analysis applies adescriptive analysis method in which the result of the analysis will be described clearly. From teh presented description, it will show how the main character of this work lives his life and in his interaction with other characters will describe his mental condition.   Keywords: Pygmalion, psychoanalisis, Narcisism, Oedipus Complex.    Abstrak Tulisan ini menganalisis kasus Narsisme dan Kompleks Oedipus yang tergambar pada sebuah karya sastra berjudul Pygmalion yang ditulis oleh George  Bernard Shaw.  Maka tujuan penelitian ini adalah untuk memperlihatkan dan menganalisis bagaimana kasus narsisme dan kompleks oedipus yang dialami oleh tokoh utama karya ini. Untuk mencapai tujuan itu, kajian ini menerapkan kajian psikoanalisis  untuk memperlihatkan kondisi kejiwaan tokoh utama yang mengalami gangguan jiwa yang dimanakan Narsisime dan Kompleks Oedipus.  Kajian ini menerapkan metode deskriptif analisis dimana hasil analisis akan dideskripsikan dengan jelas. Dari deskripsi yang dijabarkan akan memperlihatkan bagaimana tokoh utama karya ini dalam kehidupannya dan interaksinya dengan tokoh yang lain memperlihatkan kondisi jiwanya.   Kata Kunci: Pygmalion, Psikoanalisis. Narsisime, Kompleks Oedipus

  15. Shared Learning and the Drive to Improve Patient Safety: Lessons Learned from the Pittsburgh Regional Healthcare Initiative

    Sirio, Carl A; Keyser, Donna J; Norman, Heidi; Weber, Robert J; Muto, Carlene A

    2005-01-01

    Based on lessons learned through implementation of the Pittsburgh Regional Healthcare Initiative's region-wide shared learning model, we have identified the environmental, cultural, and infrastructure...

  16. High Energy Ion Bombardment Simulation Facility at the University of Pittsburgh

    McGruer, J.N.; Choyke, W.J.; Doyle, N.J.; Spitznagel, J.A.

    1975-01-01

    The High Energy Ion Bombardment Simulation (HEIBS) Facility located at the University of Pittsburgh is now operational. The E-22 tandem accelerator of the Nuclear Physics Laboratory, fitted with a UNIS source, provides the heavy high energy ions. An auxiliary Van de Graaff accelerator is used for the simultaneous production of He ions. Special features of the simulation laboratory are reported

  17. 77 FR 77016 - Foreign-Trade Zone 33 - Pittsburgh, Pennsylvania Notification of Proposed Export Production...

    2012-12-31

    ... Confectionery Bars) Pittsburgh, PA Tsudis Chocolate Company (Tsudis), an operator of FTZ 33, submitted a... the facility would involve the production of chocolate confectionery bars for export (no shipments for... markets, FTZ procedures could exempt Tsudis from customs duty payments on the foreign status material used...

  18. 78 FR 22285 - Notice of Inventory Completion: Carnegie Museum of Natural History, Pittsburgh, PA

    2013-04-15

    ....R50000] Notice of Inventory Completion: Carnegie Museum of Natural History, Pittsburgh, PA AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Carnegie Museum of Natural History has... associated funerary objects should submit a written request to the Carnegie Museum of Natural History. If no...

  19. Past, Present, and Future Research Avenues for Metformin

    Sparkes, Steven T.; Patel, Dhiren K.

    2014-01-01

    Objective: To review why metformin is considered first-line therapy for type 2 diabetes mellitus (T2DM) and review newer avenues of research currently being evaluated. Data Sources: The Cochrane Library and Medline (to January 2014) were searched for case–control and cohort studies, clinical trials, and systematic reviews and meta-analyses involving metformin for any indication. Study Selection and Data Extraction: The literature search found 5 major avenues of research for metformin: reduction in mortality, delayed-onset or prevention of T2DM in the presence of prediabetes, nonalcoholic fatty liver disease (NAFLD), polycystic ovarian syndrome (PCOS), and decreased cancer risk. When available, multi-center, double-blind, controlled clinical trials or meta-analyses thereof were selected for review. If these types of studies did not exist, other types of studies were chosen for review. Data Synthesis: Metformin significantly decreases all-cause and diabetes-related mortality in overweight and obese patients with T2DM. It may also decrease risk of progression to T2DM in patients with prediabetes. Metformin has been studied for the treatment of NAFLD though data are limited. Metformin alone or combined with clomiphene may increase pregnancy and ovulation rates but has not yet been shown to increase live-birth rates in patients with PCOS. Metformin may decrease risk of colorectal cancer but not all-cancer risk. Conclusions: Metformin’s clinical role in T2DM and prediabetes is well established. Other avenues of research being evaluated at this time are NAFLD, PCOS, and reduced risk of cancer; more data are needed before it has a clinical role in these indications.

  20. Wavelength selection in injection-driven Hele-Shaw flows: A maximum amplitude criterion

    Dias, Eduardo; Miranda, Jose

    2013-11-01

    As in most interfacial flow problems, the standard theoretical procedure to establish wavelength selection in the viscous fingering instability is to maximize the linear growth rate. However, there are important discrepancies between previous theoretical predictions and existing experimental data. In this work we perform a linear stability analysis of the radial Hele-Shaw flow system that takes into account the combined action of viscous normal stresses and wetting effects. Most importantly, we introduce an alternative selection criterion for which the selected wavelength is determined by the maximum of the interfacial perturbation amplitude. The effectiveness of such a criterion is substantiated by the significantly improved agreement between theory and experiments. We thank CNPq (Brazilian Sponsor) for financial support.

  1. Billy Shaw Dam and Reservoir: Environmental assessment and finding of no significant impacts

    1997-03-01

    This notice announces BPA's decision to fund the construction, operation, and maintenance of the Billy Shaw Dam and Reservoir on the Duck Valley Reservation. This project is part of a continuing effort to address system-wide fish and wildlife losses caused by the development of the hydropower system in the Columbia River Basin. BPA has prepared an Environmental Assessment (EA) evaluating the potential environmental impacts of the proposed project. Based on the analysis in the EA, BPA has determined that the Proposed Action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement (EIS) is not required and BPA is issuing this FONSI

  2. Universality Results for Multi-Layer Hele-Shaw and Porous Media Flows

    Daripa, Prabir

    2012-11-01

    Saffman-Taylor instability is a well known viscosity driven instability of an interface. Motivated by a need to understand the effect of various injection policies currently in practice for chemical enhanced oil recovery, we study linear stability of displacement processes in a Hele-Shaw cell involving injection of an arbitrary number of immiscible fluid phases in succession. This is a problem involving many interfaces. Universal stability results have been obtained for this multi-layer (multi-region) flow in the sense that the results hold with arbitrary number of interfaces. These stability results have been applied to design injection policies that are considerably less unstable than the pure Saffman-Taylor case. In particular, we determine specific values of the viscosity of the fluid layers corresponding to smallest unstable band. Moreover, we discuss universal selection principle of optimal viscous profiles. The talk is based on following papers. Qatar National Fund (a member of the Qatar Foundation).

  3. Universality Results for Multi-layer Radial Hele-Shaw Flows

    Daripa, Prabir; Gin, Craig; Daripa Research Team

    2014-03-01

    Saffman-Taylor instability is a well known viscosity driven instability of an interface separating two immiscible fluids. We study linear stability of this displacement process in multi-layer radial Hele-Shaw geometry involving an arbitrary number of immiscible fluid phases. Universal stability results have been obtained and applied to design displacement processes that are considerably less unstable than the pure Saffman-Taylor case. In particular, we derive universal formula which gives specific values of the viscosities of the fluid layers corresponding to smallest unstable band. Other similar universal results will also be presented. The talk is based on ongoing work. Supported by an NPRP Grant # 08-777-1-141 from the Qatar National Research Fund (a member of the Qatar Foundation). The statements made herein are solely the responsibility of the authors.

  4. Shocks and finite-time singularities in Hele-Shaw flow

    Teodorescu, Razvan [Los Alamos National Laboratory; Wiegmann, P [UNIV OF MONTREAL; Lee, S-y [UNIV OF CHICAGO

    2008-01-01

    Hele-Shaw flow at vanishing surface tension is ill-defined. In finite time, the flow develops cusplike singularities. We show that the ill-defined problem admits a weak dispersive solution when singularities give rise to a graph of shock waves propagating in the viscous fluid. The graph of shocks grows and branches. Velocity and pressure jump across the shock. We formulate a few simple physical principles which single out the dispersive solution and interpret shocks as lines of decompressed fluid. We also formulate the dispersive solution in algebro-geometrical terms as an evolution of Krichever-Boutroux complex curve. We study in details the most generic (2,3) cusp singularity which gives rise to an elementary branching event. This solution is self-similar and expressed in terms of elliptic functions.

  5. Billy Shaw Dam and Reservoir : Environmental Assessment and Finding of No Significant Impacts.

    United States. Bonneville Power Administration; Shoshone-Paiute Tribes of the Duck Valley Reservation, Nevada.

    1997-03-01

    This notice announces BPA`s decision to fund the construction, operation, and maintenance of the Billy Shaw Dam and Reservoir on the Duck Valley Reservation. This project is part of a continuing effort to address system-wide fish and wildlife losses caused by the development of the hydropower system in the Columbia River Basin. BPA has prepared an Environmental Assessment (EA) evaluating the potential environmental impacts of the proposed project. Based on the analysis in the EA, BPA has determined that the Proposed Action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement (EIS) is not required and BPA is issuing this FONSI.

  6. A study of gas bubbles in liquid mercury in a vertical Hele-Shaw cell

    Klaasen, B.; Blanpain, B. [KU Leuven, Research Group for High Temperature Processes and Industrial Ecology, Department of Metallurgy and Materials Engineering, Leuven (Belgium); Verhaeghe, F. [KU Leuven, Research Group for High Temperature Processes and Industrial Ecology, Department of Metallurgy and Materials Engineering, Leuven (Belgium); Umicore Group Research and Development, Olen (Belgium); Fransaer, J. [KU Leuven, Research Group for Materials with Novel Functionality, Department of Metallurgy and Materials Engineering, Leuven (Belgium)

    2014-01-15

    High-quality observations of mesoscopic gas bubbles in liquid metal are vital for a further development of pyrometallurgical gas injection reactors. However, the opacity of metals enforces the use of indirect imaging techniques with limited temporal or spatial resolution. In addition, accurate interface tracking requires tomography which further complicates the design of a high-temperature experimental setup. In this paper, an alternative approach is suggested that circumvents these two main restrictions. By injecting gas in a thin layer of liquid metal entrapped between two flat and closely spaced plates, bubbles in a Hele-Shaw flow regime are generated. The resulting quasi-2D multiphase flow phenomena can be fully captured from a single point of view and, when using a non-wetted transparent plate material, the bubbles can be observed directly. The feasibility of this approach is demonstrated by observations on buoyancy-driven nitrogen bubbles in liquid mercury in a vertical Hele-Shaw cell. By using a moving high-speed camera to make continuous close up recordings of individual bubbles, the position and geometry of these bubbles are quantified with a high resolution along their entire path. After a thorough evaluation of the experimental accuracy, this information is used for a detailed analysis of the bubble expansion along the path. While the observed bubble growth is mainly caused by the hydrostatic pressure gradient, a careful assessment of the volume variations for smaller bubbles shows that an accurate bubble description should account for significant dynamic pressure variations that seem to be largely regime dependent. (orig.)

  7. Tsunakawa-Shaw method - an absolute paleointensity technique using alternating field demagnetization

    Yamamoto, Y.; Mochizuki, N.; Shibuya, H.; Tsunakawa, H.

    2015-12-01

    Among geologic materials volcanic rocks have been typically used to deduce an absolute paleointensity. In the last decade, however, there seems a becoming consensus that volcanic rocks are not so ideal materials due to such as magnetic grains other than non-interacting single domain particles. One approach to obtain a good paleointensity estimate from the rocks is to reduce and correct the non-ideality, suppress alterations in laboratory and screen out suspicious results. We have been working on a development and an application of the Tsunakawa-Shaw method, which has been previously called the LTD-DHT Shaw method. This method is an AF(alternating field)-based technique and thus a paleointensity is estimated using coercivity spectra. To reduce the non-ideality, all remanences undergo low-temperature demagnetization (LTD) before any AF demagnetizations to remove multi-domain like component. To correct the non-ideality, anhysteretic remanent magnetizations (ARMs) are imparted with their directions parallel to natural remanent magnetizations and laboratory-imparted thermoremanent magnetizations (TRMs) and measured before and after laboratory heating. These ARMs are used to correct remanence anisotropies, possible interaction effects originated from the non-ideal grains and TRM changes caused by laboratory alterations. TRMs are imparted by heating specimens above their Curie temperatures and then cooling to room temperature at once to simulate nature conditions. These cycles are done in vacuum to suppress alterations in laboratory. Obtained results are judged by selection criteria, including a check for validity of the ARM corrections.It has been demonstrated that successful paleointensities are obtained from historical lavas in Japan and Hawaii, and from baked clay samples from a reconstructed ancient kiln, with the flow-mean precision of 5-10%. In case of old volcanic rocks, however, the method does not necessarily seem to be perfect. We will summarize these points in

  8. Customer perceived value—Conceptualization and avenues for future research

    Alexander Zauner

    2015-12-01

    Full Text Available Given the present dynamic consumption environment due to technological innovations as well as interlinked economic developments on the macro-, micro-, and societal-level, researchers and managers have been increasingly showing interest in the concept of customer perceived value. However, especially given its vast empirical application, surprisingly little effort has been paid to synthesize various perspectives on the dimensionality, abstraction, and model taxonomy of customer perceived value. Therefore, based on a comprehensive literature review, this article identifies the predominant conceptualization of customer perceived value, thus also providing a sound basis for future empirical assessments of this concept, and discusses avenues for future research. In addition to contributing to research, this study also contributes to practice by comprehensively positioning customer perceived value as a key source of competitive advantage in the context of relationship marketing, management, and business models.

  9. Concentration of metals adjacent to Tiete river border avenues

    Silva, Natalia C. e; Figueiredo, Ana M.G.; Ribeiro, Andreza P.; Nammoura Neto, Georges M.; Camargo, Sonia P.; Ticianelli, Regina B.

    2009-01-01

    This work analysed different 5 cm depth fragments soils, with distinct characteristic s, collected at 8 points of the Tiete river marginal avenue at the Sao Paulo metropolitan region. The technique used for the analysis was the instrumental neutron activation analysis (INAA). Together with samples, metal concentration were measured in three reference materials BEN (IWG-GIT), GS-N (IWG-GIT) and Soil-7 (IAEA) for quality control of the results. These metals were analysed: arsenic (As), barium (Ba), chromium (Cr), cobalt (Co), antimony (Sb) e zinc (Zn); the obtained concentrations were compared with intervention limit values stipulated by the Companhia de Tecnologia de Saneamento Ambiental (CETESB). Those values indicate the soil quality for different use

  10. 76 FR 51029 - Proposed CERCLA Administrative Cost Recovery Settlement; Carpenter Avenue Mercury Site, Iron...

    2011-08-17

    ... Settlement; Carpenter Avenue Mercury Site, Iron Mountain, Dickenson County, MI AGENCY: Environmental... of past response costs concerning the Carpenter Avenue Mercury site in Iron Mountain, Dickenson...., mail code: C-14J, Chicago, Illinois 60604. Comments should reference the Carpenter Avenue Mercury site...

  11. Structural validity of the Pittsburgh Sleep Quality Index in Chinese undergraduate students: A confirmatory factor analysis

    Suran Guo

    2016-08-01

    Full Text Available The purpose of this study was to examine the structural validity of the Pittsburgh Sleep Quality Index (PSQI in Chinese undergraduate students. A cross-sectional questionnaire survey with 631 Chinese undergraduate students was conducted, and the questionnaire package included a measure of demographic characteristics, Pittsburgh Sleep Quality Index (PSQI, Chinese editions of Center for Epidemiologic Studies-Depression, State- Trait Anxiety Inventory, Rumination Response Scale, and Perceived Social Support Scale. Results showed that the item use of sleep medicine was not suitable for use with this population, that a two-factor model provided the best fit to the data as assessed through confirmatory factor analysis, and that other indices were consistently correlated with the sleep quality but not the sleep efficiency factor.

  12. Cation ordering in orthopyroxenes and cooling rates of meteorites: Low temperature cooling rates of Estherville, Bondoc and Shaw

    Ganguly, J.; Yang, H.; Ghose, S.

    1993-01-01

    The cooling rates of meteorites provide important constraints on the size of their parent bodies, and their accretionary and evolutionary histories. However, the cooling rates obtained so far from the commonly used metallographic, radiometric and fission-track methods have been sometimes quite controversial, such as in the case of the mesosiderites and the meteorite Shaw. We have undertaken a systematic study of the cooling rates of meteorites using a different approach, which involves single crystal x-ray determination of Fe(2+)-Mg ordering in orthopyroxenes (OP(x)) in meteorites, subject to bulk compositional constraints, and numerical simulation of the evolution of the ordering state as a function of cooling rate, within the framework of the thermodynamic and kinetic principles governing cation ordering. We report the results obtained for OP(x) crystals from Shaw and two mesosiderites, Estherville and Bondoc.

  13. Pittsburgh Regional Healthcare Initiative puts new spin on improving healthcare quality.

    2002-11-01

    For nearly 4 years, the Pittsburgh Regional Healthcare Initiative (PRHI) has been working to improve the way healthcare is delivered in southwestern Pennsylvania by combining the voices and resources of hospitals, providers, the business community, insurers, health plans, and federal agencies. As one example of borrowing from business, the PRHI has created a new learning and management system, called Perfecting Patient Care, which is based on the Toyota Production System model and is now being used successfully in hospitals.

  14. Structural Validity of the Pittsburgh Sleep Quality Index in Chinese Undergraduate Students

    Guo, Suran; Sun, Wenmei; Liu, Chang; Wu, Siwei

    2016-01-01

    The purpose of this study was to examine the structural validity of the Pittsburgh Sleep Quality Index (PSQI) in Chinese undergraduate students. A cross-sectional questionnaire survey with 631 Chinese undergraduate students was conducted, and the questionnaire package included a measure of demographic characteristics, PSQI, Chinese editions of Center for Epidemiologic Studies-Depression, State- Trait Anxiety Inventory, Rumination Response Scale, and Perceived Social Support Scale. Results sho...

  15. The ethics of killing human/great-ape chimeras for their organs: a reply to Shaw et al.

    Palacios-González, César

    2016-06-01

    The aim of this paper is to critically examine David Shaw, Wybo Dondorp, and Guido de Wert's arguments in favour of the procurement of human organs from human/nonhuman-primate chimeras, specifically from great-ape/human chimeras. My main claim is that their arguments fail and are in need of substantial revision. To prove this I first introduce the topic, and then reconstruct Shaw et al.'s position and arguments. Next, I show that Shaw et al.: (1) failed to properly apply the subsidiarity and proportionality principles; (2) neglected species overlapping cases in their ethical assessment; (3) ignored the ethics literature on borderline persons; and (4) misunderstood McMahan's two-tiered moral theory. These mistakes render an important part of their conclusions either false or problematic to the point that they would no longer endorse them. Finally I will briefly mention a possible multipolar solution to the human organ shortage problem that would reduce the need for chimeras' organs.

  16. Prosperity in Pittsburgh. Special Librarians Gather to Reaffirm the Ties that Bind this Varied and Growing Association

    Library Journal, 1973

    1973-01-01

    Everything, for the second year in a row, seemed to be looking up for the Special Libraries Association as it gathered in Pittsburgh in June. This article is a brief report on the conference. (Author/SJ)

  17. Propagation of a finite bubble in a Hele-Shaw channel of variable depth

    Juel, Anne; Franco-Gomez, Andres; Thompson, Alice; Hazel, Andrew

    2017-11-01

    We study the propagation of finite bubbles in a Hele-Shaw channel, where a centred rail is introduced to provide a small axially-uniform depth constriction. We demonstrate experimentally that this channel geometry can be used as a passive sorting device. Single air bubbles carried within silicone oil are generally transported on one side of the rail. However, for flow rates marginally larger than a critical value, a narrow band of bubble sizes on the order of the rail width can propagate over the rail, while bubbles of other sizes segregate to the side of the rail. The width of this band of bubble sizes increases with flow rate and the size of the most stable bubble can be tuned by varying the rail width. We present a depth-averaged theory which reveals that the mechanism relies on a non-trivial interaction between capillary and viscous forces that is fully dynamic, rather than being a simple modification of capillary static solutions. In contrast, for larger bubbles and sufficiently large imposed flow rates, we find that initially centred bubbles do not converge onto a steady mode of propagation. Instead they transiently explore weakly unstable steady modes, an evolution which results in their break-up and eventual settling into a steady state of changed topology. The financial support of CONICYT and the Leverhulme Trust are gratefully acknowledged.

  18. Instability of displacement of Oldroyd-B fluid by air in a Hele-Shaw cell

    Daripa, Prabir

    2014-03-01

    We study the displacement of an Oldroyd-B fluid in a Hele-Shaw cell when driven by air. In particular, we explicitly obtain an analytical expression for the growth rate of instability which depends on the relaxation and retardation (time) constants, denoted by λ, and λ1 respectively, appearing in the Oldroyd-B constitutive relations. When these two constants are zero, we recover the classical Saffman-Taylor result for a Newtonian liquid displaced by air. Our results show that this displacement process is more unstable than the case when a Newtonian fluid is displaced by air. The analytical results are plotted and compared with numerical results on this unstable displacement process available in the literature. The agreement is found to be excellent. In particular, results show that the non-Newtonian case (i.e., Oldroyd-B) is more unstable than the Newtonian case. Supported by an NPRP Grant # 08-777-1-141 from the Qatar National Research Fund (a member of the Qatar Foundation). The statements made herein are solely the responsibility of the author.

  19. Interfacial elastic fingering in Hele-Shaw cells: A weakly nonlinear study

    Carvalho, Gabriel D.

    2013-11-11

    We study a variant of the classic viscous fingering instability in Hele-Shaw cells where the interface separating the fluids is elastic, and presents a curvature-dependent bending rigidity. By employing a second-order mode-coupling approach we investigate how the elastic nature of the interface influences the morphology of emerging interfacial patterns. This is done by focusing our attention on a conventionally stable situation in which the fluids involved have the same viscosity. In this framework, we show that the inclusion of nonlinear effects plays a crucial role in inducing sizable interfacial instabilities, as well as in determining the ultimate shape of the pattern-forming structures. Particularly, we have found that the emergence of either narrow or wide fingers can be regulated by tuning a rigidity fraction parameter. Our weakly nonlinear findings reinforce the importance of the so-called curvature weakening effect, which favors the development of fingers in regions of lower rigidity. © 2013 American Physical Society.

  20. Interfacial elastic fingering in Hele-Shaw cells: A weakly nonlinear study

    Carvalho, Gabriel D.; Miranda, José A.; Gadê lha, Hermes

    2013-01-01

    We study a variant of the classic viscous fingering instability in Hele-Shaw cells where the interface separating the fluids is elastic, and presents a curvature-dependent bending rigidity. By employing a second-order mode-coupling approach we investigate how the elastic nature of the interface influences the morphology of emerging interfacial patterns. This is done by focusing our attention on a conventionally stable situation in which the fluids involved have the same viscosity. In this framework, we show that the inclusion of nonlinear effects plays a crucial role in inducing sizable interfacial instabilities, as well as in determining the ultimate shape of the pattern-forming structures. Particularly, we have found that the emergence of either narrow or wide fingers can be regulated by tuning a rigidity fraction parameter. Our weakly nonlinear findings reinforce the importance of the so-called curvature weakening effect, which favors the development of fingers in regions of lower rigidity. © 2013 American Physical Society.

  1. Rayleigh-Benard convection in a Hele-Shaw cell - a numerical study

    Guenther, C.; Mueller, U.

    1987-05-01

    Free convection in narrow vertical gaps heated from below gives rise to several different flow patterns as has been demonstrated by previous experimental investigations. A numerical study is presented aimed at simulating the observed flow phenomena in Hele-Shaw cells of small lateral extend. The numerical study is based on the assumption that the flow is essentially two-dimensional. This allows an approach using a one-term Galerkin approximation with respect to the direction perpendicular to the gap and a finite difference scheme with regard to the coordinates in the plane of the gap. The calculations result in realistic values of the critical Rayleigh numbers for the onset of steady and oscillatory convection. Most of the observed unsteady flow patterns can be simulated numerically. It is shown that five different stable flow patterns can occur at one particular Rayleigh number. The different stable flow patterns are coupled by a variety of complex transitions. Moreover the calculations show that a realistic description of the observed flow phenomena can not be obtained by a simplified model using the Darcy law in the momentum equation and implying slip flow at the small confining boundaries. (orig.) [de

  2. Structure of thallium and lead calculated from Shaw local pseudopotential and molecular dynamics

    Gasser J. G.

    2011-05-01

    Full Text Available Recently, we (Es Sbihi Phil. Mag 2010 have successfully calculated, by molecular dynamics, the static structure factor of liquid bismuth at different temperatures. Our results were in very good agreement with the Waseda experimental data. Our assumption was to consider the true density of states which presents a gap as measured by Indlekofer (J. Non-Cryst. Solids 1989 and calculated by Hafner-Jank (Phys. Rev. B 1990 for liquid bismuth. The number of electrons at the Fermi energy has been calculated with three conduction electrons for bismuth (number of p electrons. With this assumption, the structures were determined with an effective ion-ion potential constructed from the Shaw local Optimised Model Potential (OMP and the Ichimaru-Utsumi dielectric function. In the present paper, we generalize our assumptions to liquid thallium and lead which also present such a gap. Their calculated structures are also very close to the experimental ones. This confirms that the number of conduction electrons on the Fermi sphere is consistent with the number of p electrons as has been even shown for our electronic transport properties of liquid lead (A. Ben Abdellah, Phys. Rev. B 2003.

  3. Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study

    Leuzy, Antoine; Chiotis, Konstantinos; Hasselbalch, Steen G

    2016-01-01

    subjects with normal cognition and patients with mild cognitive impairment, Alzheimer's disease dementia, frontotemporal dementia, and vascular dementia. All had Pittsburgh compound B positron emission tomography data, cerebrospinal fluid INNOTEST amyloid-β42 values, and cerebrospinal fluid samples...... uptake value ratio results were scaled using the Centiloid method. Concordance between Meso Scale Discovery/mass spectrometry reference measurement procedure findings and Pittsburgh compound B was high in subjects with mild cognitive impairment and Alzheimer's disease, while more variable results were...

  4. Therapeutic avenues for hereditary forms of retinal blindness.

    Kannabiran, Chitra; Mariappan, Indumathi

    2018-03-01

    Hereditary retinal diseases, known as retinal degenerations or dystrophies, are a large group of inherited eye disorders resulting in irreversible visual loss and blindness. They develop due to mutations in one or more genes that lead to the death of the retinal photoreceptor cells. Till date, mutations in over 200 genes are known to be associated with all different forms of retinal disorders. The enormous genetic heterogeneity of this group of diseases has posedmany challenges in understanding the mechanisms of disease and in developing suitable therapies. Therapeutic avenues that are being investigated for these disorders include gene therapy to replace the defective gene, treatment with neurotrophic factors to stimulate the growth of photoreceptors, cell replacement therapy, and prosthetic devices that can capture light and transmit electrical signals through retinal neurons to the brain. Several of these are in process of human trials in patients, and have shown safety and efficacy of the treatment. A combination of approaches that involve both gene replacement and cell replacement may be required for optimum benefit.

  5. Chronological development avenues in biotechnology across the world

    Prashant Y Mali

    2011-01-01

    Full Text Available Biotechnology is expected to be a great technological revolution followed by information technology. It is an application of scientific and engineering principles to the processing of material by biological agents to provide better goods and services to mankind. Commercially its techniques are applied long back in 6 th century in the art of brewing, wine making and baking. It has progressed there after crossing different land marks. Modern biotechnology has developed significantly in the late 19 th century with groundbreaking discoveries applicable in medicine, food, agriculture, chemistry, environmental protection and many more industries. It is widely used in the development of high-yielding, disease-resistant, better quality varieties by applying tissue culture and recombinant DNA techniques. It has wide application in animal breeding using techniques such as artificial insemination, in vitro fertilization and embryo transfer. Specific enzymes used in laundry, fuel and leather industries for better quality, economically feasible and environmental friendly production. Biotechnology in healthcare system uses body′s own tools and weapons to fight against diseases, manufacturing of targeted therapeutic proteins, gene therapy and so on. Novel approaches such as proteomics and structural biology are contributing to understanding the chemistry of life and diseases. Malfunctioning gene replaced with correctly functioning gene by using gene therapy. Tissue engineering has opened up the use of in vitro developed tissue or organ in repairing wounded tissue and system biology which is a computer-based approach to understand cell functions. Although every new discovery related to biology and its implications is significant and has taken the technology ahead. This includes applications, commercialization, controversies, media exposure and so on. Hence, we have enlisted some of the chronological development avenues in biotechnology across the world.

  6. Building America Case Study: Evaluating Through-Wall Air Transfer Fans, Pittsburgh, Pennsylvania (Fact Sheet)

    2014-10-01

    In this project, Building America team IBACOS performed field testing in a new construction unoccupied test house in Pittsburgh, Pennsylvania to evaluate heating, ventilating, and air conditioning (HVAC) distribution systems during heating, cooling, and midseason conditions. Four air-based HVAC distribution systems were assessed:-a typical airflow ducted system to the bedrooms, a low airflow ducted system to the bedrooms, a system with transfer fans to the bedrooms, and a system with no ductwork to the bedrooms. The relative ability of each system was considered with respect to relevant Air Conditioning Contractors of America and ASHRAE standards for house temperature uniformity and stability, respectively.

  7. Elements related to attrition of women faculty at the University of Pittsburgh, School of Medicine: A case study

    Gandhi, Pooja

    Recent studies have shown that the number of women faculty in academic medicine is much lesser than the number of women that are graduating from medical schools. Many academic institutes face the challenge of retaining talented faculty and this attrition from academic medicine prevents career advancement of women faculty. This case study attempts to identify some of the reasons for dissatisfaction that may be related to the attrition of women medical faculty at the University of Pittsburgh, School of Medicine. Data was collected using a job satisfaction survey, which consisted of various constructs that are part of a faculty's job and proxy measures to gather the faculty's intent to leave their current position at the University of Pittsburgh or academic medicine in general. The survey results showed that although women faculty were satisfied with their job at the University of Pittsburgh, there are some important factors that influenced their decision of potentially dropping out. The main reasons cited by the women faculty were related to funding pressures, work-life balance, mentoring of junior faculty and the amount of time spent on clinical responsibilities. The analysis of proxy measures showed that if women faculty decided to leave University of Pittsburgh, it would most probably be due to better opportunity elsewhere followed by pressure to get funding. The results of this study aim to provide the School of Medicine at the University of Pittsburgh with information related to attrition of its women faculty and provide suggestions for implications for policy to retain their women faculty.

  8. Results of the radiological survey at the former Heppenstall Company site, 4620 Hatfield Street, Pittsburgh, Pennsylvania

    Cottrell, W.D.; Crutcher, J.W.; Quillen, J.L.

    1991-01-01

    As part of the Formerly Utilized Sites Remedial Action Program, the US Department of Energy (DOE) is implementing a program to determine the radiological conditions at sites that were used to process radioactive materials under contract with the department's predecessor agencies. During 1955 the former Heppenstall Company site in Pittsburgh, Pennsylvania, was used by an Atomic Energy Commission contractor to process approximately 100,000 lbs of normal uranium metal. Because of insufficient records to document cleanup procedures and to verify the radiological condition of this site, DOE requested a survey. The radiological survey discussed in this report for the site of the former Heppenstall Company, Pittsburgh, Pennsylvania, was conducted by members of the Measurement Applications and Development Group of Oak Ridge National Laboratory in July of 1989. The survey included a surface gamma scan of the warehouse, collection of indoor soil and dust samples and one outdoor sample, and measurement of direct and transferable alpha and beta-gamma activity. Results of this radiological assessment indicate no detection of radiation levels or radionuclide concentrations above DOE guidelines. 7 refs., 5 figs., 3 tabs

  9. The esophagus anatomic-histology of bull frog ("Rana catesbeiana" Shaw, 1802 Anatomo-histologia do esôfago da rã touro ("Rana catesbeiana" Shaw, 1802

    Carlos Eduardo Lino Pinto

    2008-04-01

    Full Text Available Aiming to describe the esophage functional morpho – histology of bull frog (Rana catebeiana Shaw, 1802, twenty bull frog, mean body weight of 85.00 ± 2.03 g, were used. The esophageal mucosa architecture is defined by thick longitudinal folds, showing an esophageal ciliated pseudostratified epithelium with mucous cells and pluricellular glands; the esophageal muscular coat is composed by inner circular muscular lamina, and by outer longitudinal muscular lamina.Com o objetivo de descrever a anatomo histologia funcional do esôfago da rã touro (Rana catesbeiana Shaw, 1802, foram utilizados 20 (vinte exemplares de rã touro com peso médio de 85,00 ± 2,03 g. Verificou-se que a arquitetura da mucosa esofágica é definida por pregas espessas e longitudinais, com epitélio esofágico do tipo pseudo estratificado ciliado com células mucosas e glândulas pluricelulares; a túnica muscular esofágica é constituida pela túnica muscular circular, mais interna, e pela túnica muscular longitudinal, mais externa.

  10. Waves on a Hele-Shaw Cell: Simulations of Acoustic Emissions During Aerofracture

    Turkaya, Semih; Toussaint, Renaud; Kvalheim Eriksen, Fredrik; Daniel, Guillaume; Grude Flekkøy, Eirik; Jørgen Måløy, Knut

    2016-04-01

    In this work, we develop a numerical model to explain the lab scale experimental setup [1] modeling the aerofractures in a porous medium. The mentioned experimental setup consists in a rectangular Hele-Shaw cell with three closed boundaries and one semi-permeable boundary which enables the flow of the fluid but not the solid particles. During the experiments, the fluid (pressurized air) is injected into the system with a constant injection pressure from the point opposite to the semi-permeable boundary. At the large enough injection pressures, the fluid also displaces grains (80 μm grain size) and creates channels and fractures towards the semi-permeable boundary. This analogue model is developed in a linear geometry, with confinement and at a lower porosity to study the instabilities developing during the fast motion of a fluid in dense porous materials: fracturing, fingering, and channeling. Different sources of the signal (air vibration in the carved area, changes in the effective stress due to fluid-solid interactions [2]) are separately analyzed and are investigated further using a far field approximation of Lamb waves presented by Goyder & White [3]. In the analysis phase, power spectrum of different timewindows (5 ms) obtained from the recorded signal are computed. Then, the evolution of this power spectrum is compared with the experimental findings. In the power spectrum, it is possible to see some characteristic structure like peaks in specific frequency ranges. These "peaks" are strongly influenced by the size and branching of the channels, compaction of the medium, vibration of air in the pores and the fundamental frequency of the plate. We found that, in the synthetic dataset, the peaks in the low frequency range (f Daniel G, Flekkøy EG, Måløy KJ. "Bridging aero-fracture evolution with the characteristics of the acoustic emissions in a porous medium." Front. Phys., 3 (2015): 70. doi: 10.3389/fphy.2015.00070 2. Niebling MJ, Toussaint R, Flekkøy EG

  11. The angle of repose of spherical grains in granular Hele–Shaw cells: a molecular dynamics study

    Maleki, Hamed; Ebrahimi, Fatemeh; Oskoee, Ehsan Nedaaee

    2008-01-01

    We report the results of three-dimensional molecular dynamic simulations on the angle of repose of a sandpile formed by pouring mono-sized cohesionless spherical grains into a granular Hele–Shaw cell. In particular, we are interested in investigating the effects of those variables which may have a significant impact on the pattern formation of granular mixtures in Hele–Shaw cells. The results indicate that the frictional forces influence the formation of piles on the grain level remarkably. Furthermore, we see that increasing grain insertion rate decreases the angle of repose slightly. We also find that the cell thickness is a significant factor and the angle of repose decays when the size of the gap between the lateral walls increases. In addition to agreeing with the experimental exponential decay law, our results are in accordance with a recently proposed model which takes into account the arching effects. Using grains with different sizes reveals that the behaviour of the angle of repose when both size and cell thickness are varied is controlled by a scaled function of the ratio of these two variables

  12. Centrifugal fingering in a curved Hele-Shaw cell: A generalized Euler's elastica shape for the two-fluid interface

    Miranda, Jose; Brandao, Rodolfo

    2017-11-01

    We study a family of generalized elastica-like equilibrium shapes that arise at the interface separating two fluids in a curved rotating Hele-Shaw cell. This family of stationary interface solutions consists of shapes that balance the competing capillary and centrifugal forces in such a curved flow environment. We investigate how the emerging interfacial patterns are impacted by changes in the geometric properties of the curved Hele-Shaw cell. A vortex-sheet formalism is used to calculate the two-fluid interface curvature, and a gallery of possible shapes is provided to highlight a number of peculiar morphological features. A linear perturbation theory is employed to show that the most prominent aspects of these complex stationary patterns can be fairly well reproduced by the interplay of just two interfacial modes. The connection of these dominant modes to the geometry of the curved cell, as well as to the fluid dynamic properties of the flow, is discussed. We thank CNPq (Brazilian Research Council) for financial support under Grant No. 304821/2015-2.

  13. Scaling crossover in thin-film drag dynamics of fluid drops in the Hele-Shaw cell

    Okumura, Ko; Yahashi, Misato; Kimoto, Natsuki

    2016-11-01

    We study both experimentally and theoretically the descending motion due to gravity of a fluid drop surrounded by another immiscible fluid in a confined space between two parallel plates, i.e., in the Hele-Shaw cell. As a result, we show a new scaling regime of a nonlinear drag friction in viscous liquid that replaces the well-known Stokes' drag friction through a clear collapse of experimental data thanks to the scaling law. In the novel regime, the dissipation in the liquid thin film formed between the drop and cell walls governs the dynamics. The crossover of this scaling regime to another scaling regime in which the dissipation inside the droplet is dominant is clearly demonstrated and a phase diagram separating these scaling regimes is presented. To be published as, Y. Yahashi, N. Kimoto and K. Okumura, Scaling crossover in thin-film drag dynamics of fluid drops in the Hele-Shaw cell, Sci. Rep.(CC BY 4.0). This research was partly supported by ImPACT Program of Council for Science, Technology and Innovation (Cabinet Office, Government of Japan).

  14. Equity in Microscale Urban Design and Walkability: A Photographic Survey of Six Pittsburgh Streetscapes

    Bradley Bereitschaft

    2017-07-01

    Full Text Available This paper explores inequity in neighborhood walkability at the micro-scale level by qualitatively examining six streetscapes in Pittsburgh, Pennsylvania. A photographic survey is used to highlight differences in the quality and design of the built environment among pairs of streetscapes with high or low social vulnerability but approximately equal quantitative Walk Scores®. The survey revealed discernable differences in the quality and maintenance of the built environment among those in more and less disadvantaged neighborhoods. This was true of several characteristics expected to affect walkability, including enclosure, transparency, complexity, and tidiness. Streetscapes in neighborhoods with high social vulnerability exhibited less contiguous street walls, fewer windows and less transparent storefronts, less well maintained infrastructure, fewer street cafés, and overall less complexity than those in neighborhoods with low social vulnerability. Implications for planning and policy are discussed.

  15. Industrial Restructuring and Urban Change in the Pittsburgh Region: Developmental, Ecological, and Socioeconomic Trade-offs

    William Haller

    2005-06-01

    Full Text Available This article traces the steel industry's restructuring during the 1980s and its consequences for older industrial regions tied historically to steel production. These regions contained large working-class communities that declined because of deindustrialization and restructuring. This article first examines the transition of the steel industry from its roots in extractive and primary manufacturing to a scrap-recycling industry that minimizes labor and raw material inputs. This transition parallels the structural changes in other industries addressed by political economic perspectives, such as the new international division of labor and globalization of production. The article then focuses on the socioeconomic and structural changes, using the Pittsburgh region as an example, including the employment and land-use consequences of deindustrialization and the relationship between losses in manufacturing employment and increases in persistent joblessness and poverty associated with growth of the urban underclass.

  16. Radon concentrations inside public and commercial buildings in the Pittsburgh area

    Cohen, B L; Kulwicki, D R; Warner, Jr, K R; Grassi, C L

    1984-09-01

    Radon concentrations in ambient air from numerous schools, stores and other public and commercial buildings in the Pittsburgh, PA, area were measured by grab sampling. This is more appropriate than using long-term integrating monitors because of the correlation between times of occupancy and Rn levels. Results indicate that Rn concentrations in these buildings are nearly an order of magnitude less than in homes, and not much higher than outdoors. Variations among sites is also much less than for homes, probably because there is less variability in ventilation and building maintenance practices. Colleges and universities have somewhat higher Rn levels and a larger degree of variability than commercial buildings or hospitals. There was no indication of higher Rn levels in cold weather than in warm weather, or of correlations with the age of the building.

  17. 1993 Effluent and environmental monitoring report for the Bettis Atomic Power Laboratory, Pittsburgh Site

    1993-01-01

    The results of the radiological and non-radiological environmental monitoring programs for 1993 at the Bettis-Pittsburgh Site are presented. The results obtained from the monitoring programs demonstrate that the existing procedures ensured that environmental releases during 1993 were in accordance with applicable Federal and State regulations. Evaluation of the environmental data indicates that the current operations at the Site continue to have no adverse effect on the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Site operations demonstrated that the dose received by any member of the public was well below the most restrictive dose limits established by the US Environmental Protection Agency and the US Department of Energy

  18. 1999 environmental monitoring report for the Bettis Atomic Power Laboratory, Pittsburgh Site

    2000-01-01

    The 1999 results for the Bettis-Pittsburgh radiological and nonradiological environmental monitoring programs are presented. The results demonstrate that the existing procedures ensured that releases to the environment during 1999 were in accordance with applicable Federal, State, County, and local regulations. Evaluation of the environmental data indicates that current operations at the Site continue to have no adverse effect on human health and the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Site operations demonstrates that the dose received by any member of the public was well below the most restrictive dose limits established by the Environmental Protection Agency, the Nuclear Regulatory Commission, and the US Department of Energy. A risk assessment of potentially exposed populations to chemical residues in the environment at the Site demonstrates that these residues do not pose any significant risk to human health or the environment

  19. 2003 Environmental Monitoring Report for the Bettis Atomic Power Laboratory Pittsburgh Site

    2003-01-01

    The 2003 results for the Bettis-Pittsburgh radiological and nonradiological environmental monitoring programs are presented. The results demonstrate that the existing procedures ensured that releases to the environment during 2003 were in accordance with applicable Federal, State, County, and local regulations. Evaluation of the environmental data indicates that current operations at the Site continue to have no adverse effect on human health and the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Site operations demonstrates that the dose received by any member of the public was well below the most restrictive dose limits established by the Environmental Protection Agency, the Nuclear Regulatory Commission, and the U.S. Department of Energy. A risk assessment of potentially exposed populations to chemical residues in the environment at the Site demonstrates that any potential risk posed by these residues in much less than the risks encountered in normal everyday life

  20. 1992 Effluent and environmental monitoring report for the Bettis Atomic Power Laboratory Pittsburgh Site

    1992-01-01

    The results of the radiological and non-radiological environmental monitoring programs for 1992 at the Bettis-Pittsburgh Site are presented. The results obtained from the monitoring programs demonstrate that the existing procedures ensured that environmental releases during 1992 were in accordance with applicable Federal and State regulations. Evaluation of the environmental data indicates that operation of the Laboratory continues to have no adverse effect on the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Laboratory operations demonstrated that the dose received by any member of the public was well below the most restrictive dose limits established by the Environmental Protection Agency and the Department of Energy

  1. 1997 environmental monitoring report for the Bettis Atomic Power Laboratory, Pittsburgh Site

    1997-01-01

    The 1997 results for the Bettis-Pittsburgh radiological and nonradiological environmental monitoring programs are presented. The results demonstrate that the existing procedures ensured that releases to the environment during 1997 were in accordance with applicable Federal, State, County, and local regulations. Evaluation of the environmental data indicates tat current operations at the Site continue to have no adverse effect on human health and the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Site operations demonstrates that the dose received by any member of the public was well below the most restrictive dose limits established by the Environmental Protection Agency, the Nuclear Regulatory Commission, and the US Department of Energy. A risk assessment of potentially exposed populations to chemical residues in the environment at the Site demonstrates that these residues do not pose any significant risk to human health or the environment

  2. 1993 Effluent and environmental monitoring report for the Bettis Atomic Power Laboratory, Pittsburgh Site

    1993-12-31

    The results of the radiological and non-radiological environmental monitoring programs for 1993 at the Bettis-Pittsburgh Site are presented. The results obtained from the monitoring programs demonstrate that the existing procedures ensured that environmental releases during 1993 were in accordance with applicable Federal and State regulations. Evaluation of the environmental data indicates that the current operations at the Site continue to have no adverse effect on the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Site operations demonstrated that the dose received by any member of the public was well below the most restrictive dose limits established by the US Environmental Protection Agency and the US Department of Energy.

  3. 1992 Effluent and environmental monitoring report for the Bettis Atomic Power Laboratory Pittsburgh Site

    1992-12-31

    The results of the radiological and non-radiological environmental monitoring programs for 1992 at the Bettis-Pittsburgh Site are presented. The results obtained from the monitoring programs demonstrate that the existing procedures ensured that environmental releases during 1992 were in accordance with applicable Federal and State regulations. Evaluation of the environmental data indicates that operation of the Laboratory continues to have no adverse effect on the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Laboratory operations demonstrated that the dose received by any member of the public was well below the most restrictive dose limits established by the Environmental Protection Agency and the Department of Energy.

  4. Radon concentrations inside public and commercial buildings in the Pittsburgh area.

    Cohen, B L; Kulwicki, D R; Warner, K R; Grassi, C L

    1984-09-01

    Radon concentrations in ambient air from numerous schools, stores and other public and commercial buildings in the Pittsburgh, PA, area were measured by grab sampling. This is more appropriate than using long-term integrating monitors because of the correlation between times of occupancy and Rn levels. Results indicate that Rn concentrations in these buildings are nearly an order of magnitude less than in homes, and not much higher than outdoors. Variations among sites is also much less than for homes, probably because there is less variability in ventilation and building maintenance practices. Colleges and universities have somewhat higher Rn levels and a larger degree of variability than commercial buildings or hospitals. There was no indication of higher Rn levels in cold weather than in warm weather, or of correlations with the age of the building.

  5. Prevalence of Clostridium difficile in uncooked ground meat products from Pittsburgh, Pennsylvania.

    Curry, Scott R; Marsh, Jane W; Schlackman, Jessica L; Harrison, Lee H

    2012-06-01

    The prevalence of Clostridium difficile in retail meat samples has varied widely. The food supply may be a source for C. difficile infections. A total of 102 ground meat and sausage samples from 3 grocers in Pittsburgh, PA, were cultured for C. difficile. Brand A pork sausages were resampled between May 2011 and January 2012. Two out of 102 (2.0%) meat products initially sampled were positive for C. difficile; both were pork sausage from brand A from the same processing facility (facility A). On subsequent sampling of brand A products, 10/19 samples from processing facility A and 1/10 samples from 3 other facilities were positive for C. difficile. The isolates recovered were inferred ribotype 078, comprising 6 genotypes. The prevalence of C. difficile in retail meat may not be as high as previously reported in North America. When contamination occurs, it may be related to events at processing facilities.

  6. Creating an infrastructure for training in the responsible conduct of research: the University of Pittsburgh's experience.

    Barnes, Barbara E; Friedman, Charles P; Rosenberg, Jerome L; Russell, Joanne; Beedle, Ari; Levine, Arthur S

    2006-02-01

    In response to public concerns about the consequences of research misconduct, academic institutions have become increasingly cognizant of the need to implement comprehensive, effective training in the responsible conduct of research (RCR) for faculty, staff, students, and external collaborators. The ability to meet this imperative is challenging as universities confront declining financial resources and increasing complexity of the research enterprise. The authors describe the University of Pittsburgh's design, implementation, and evaluation of a Web-based, institution-wide RCR training program called Research and Practice Fundamentals (RPF). This project, established in 2000, was embedded in the philosophy, organizational structure, and technology developed through the Integrated Advanced Information Management Systems grant from the National Library of Medicine. Utilizing a centralized, comprehensive approach, the RPF system provides an efficient mechanism for deploying content to a large, diverse cohort of learners and supports the needs of research administrators by providing access to information about who has successfully completed the training. During its first 3 years of operation, the RPF served over 17,000 users and issued more than 38,000 training certificates. The 18 modules that are currently available address issues required by regulatory mandates and other content areas important to the research community. RPF users report high levels of satisfaction with content and ease of using the system. Future efforts must explore methods to integrate non-RCR education and training into a centralized, cohesive structure. The University of Pittsburgh's experience with the RPF demonstrates the importance of developing an infrastructure for training that is comprehensive, scalable, reliable, centralized, affordable, and sustainable.

  7. Using a Merit-Based Scholarship Program to Increase Rates of College Enrollment in an Urban School District: The Case of the Pittsburgh Promise

    Bozick, Robert; Gonzalez, Gabriella; Engberg, John

    2015-01-01

    The Pittsburgh Promise is a scholarship program that provides $5,000 per year toward college tuition for public high school graduates in Pittsburgh, Pennsylvania who earned a 2.5 GPA and a 90% attendance record. This study used a difference-in-difference design to assess whether the introduction of the Promise scholarship program directly…

  8. Henry Selby Hele-Shaw LLD, DSc, EngD, FRS, WhSch (1854-1941: Engineer, inventor and educationist

    Jane Carruthers

    2010-03-01

    Full Text Available H.S. Hele-Shaw (1854–1941 was one of the most outstanding engineering scientists of his generation and an eminent figure in engineering education during the late-19th and early-20th centuries. His work in hydrodynamics (the Hele-Shaw cell and Hele-Shaw pump and his important contribution to the successful development of high-speed aircraft (his variable pitch airscrew, continues to be relevant today. In 1922, as President of the Institution of Mechanical Engineers, he introduced the National Certificate scheme in Britain. It is not well known that Hele-Shaw spent two years in South Africa (1904–1905 attached to the Transvaal Technical Institute, a forerunner of the University of the Witwatersrand. One of only three Fellows of the Royal Society of London in southern Africa in 1905, he was a founder Council member of the Royal Society of South Africa and one of the hosts of the 1905 visit to southern Africa by the British Association for the Advancement of Science. The purpose of this paper is to highlight the time he spent in South Africa and to contextualise it within the larger perspective of his engineering career.

  9. Experimental elementary particle physics at the University of Pittsburgh: Progress report, April 1, 1987-March 31, 1988

    Cleland, W.E.; Coon, D.D.; Engels, E. Jr.; Shepard, P.F.; Thompson, J.A.

    1987-12-01

    This paper discusses research activity at the University of Pittsburgh in experimental elementary particle physics. The three main tasks included are: Study of lepton production at the SPS and study of large P/sub T/ direct photon production at the ISR; Direct photon production at the Fermi Tevatron; and Search for fractional charge particles in semiconductors

  10. [Proceedings of the] International Conference on Educational Data Mining (EDM) (3rd, Pittsburgh, PA, July 11-13, 2010)

    Baker, Ryan S. J. d., Ed.; Merceron, Agathe, Ed.; Pavlik, Philip I., Jr., Ed.

    2010-01-01

    The Third International Conference on Data Mining (EDM 2010) was held in Pittsburgh, PA, USA. It follows the second conference at the University of Cordoba, Spain, on July 1-3, 2009 and the first edition of the conference held in Montreal in 2008, and a series of workshops within the AAAI, AIED, EC-TEL, ICALT, ITS, and UM conferences. EDM 2011…

  11. 78 FR 69878 - AT&T Corporation, a Subsidiary of AT&T Inc., Business Billing Customer Care, Pittsburgh...

    2013-11-21

    ... Subsidiary of AT&T Inc., Business Billing Customer Care, Pittsburgh, Pennsylvania; Notice of Affirmative... workers and former workers of AT&T Corporation, a subsidiary of AT&T Inc., Business Billing Customer Care... supplied by Business Billing Customer Care to other locations within the United States. With respect to...

  12. Numerical simulation of particle jet formation induced by shock wave acceleration in a Hele-Shaw cell

    Osnes, A. N.; Vartdal, M.; Pettersson Reif, B. A.

    2018-05-01

    The formation of jets from a shock-accelerated cylindrical shell of particles, confined in a Hele-Shaw cell, is studied by means of numerical simulation. A number of simulations have been performed, systematically varying the coupling between the gas and solid phases in an effort to identify the primary mechanism(s) responsible for jet formation. We find that coupling through drag is sufficient for the formation of jets. Including the effect of particle volume fraction and particle collisions did not alter the general behaviour, but had some influence on the length, spacing and number of jets. Furthermore, we find that the jet selection process starts early in the dispersal process, during the initial expansion of the particle layer.

  13. Of mice and men: evolution and the socialist utopia. William Morris, H.G. Wells, and George Bernard Shaw.

    Hale, Piers J

    2010-01-01

    During the British socialist revival of the 1880s competing theories of evolution were central to disagreements about strategy for social change. In News from Nowhere (1891), William Morris had portrayed socialism as the result of Lamarckian processes, and imagined a non-Malthusian future. H.G. Wells, an enthusiastic admirer of Morris in the early days of the movement, became disillusioned as a result of the Malthusianism he learnt from Huxley and his subsequent rejection of Lamarckism in light of Weismann's experiments on mice. This brought him into conflict with his fellow Fabian, George Bernard Shaw, who rejected neo-Darwinism in favour of a Lamarckian conception of change he called "creative evolution."

  14. Economic impact and policy implications from urban shared transportation: The case of Pittsburgh's shared bike system.

    Pelechrinis, Konstantinos; Zacharias, Christos; Kokkodis, Marios; Lappas, Theodoros

    2017-01-01

    During the last years the number of cities that have installed and started operating shared bike systems has significantly increased. These systems provide an alternative and sustainable mean of transportation to the city dwellers. Apart from the energy sustainability benefits, shared bike systems can have a positive effect on residents' health, air quality and the overall condition of the currently crumbling road network infrastructure. Anecdotal stories and survey studies have also identified that bike lanes have a positive impact on local businesses. In this study, driven by the rapid adoption of shared bike systems by city governments and their potential positive effects on a number of urban life facets we opt to study and quantify the value of these systems. We focus on a specific aspect of this value and use evidence from the real estate market in the city of Pittsburgh to analyze the effect on dwellers' properties of the shared bike system installed in the city in June 2015. We use quasi-experimental techniques and find that the shared bike system led to an increase in the housing prices (both sales and rental prices) in the zip codes where shared bike stations were installed. We further bring into the light potential negative consequences of this impact (i.e., gentrification) and discuss/propose two public policies that can exploit the impact of the system for the benefit of both the local government as well as the city dwellers.

  15. Economic impact and policy implications from urban shared transportation: The case of Pittsburgh's shared bike system.

    Konstantinos Pelechrinis

    Full Text Available During the last years the number of cities that have installed and started operating shared bike systems has significantly increased. These systems provide an alternative and sustainable mean of transportation to the city dwellers. Apart from the energy sustainability benefits, shared bike systems can have a positive effect on residents' health, air quality and the overall condition of the currently crumbling road network infrastructure. Anecdotal stories and survey studies have also identified that bike lanes have a positive impact on local businesses. In this study, driven by the rapid adoption of shared bike systems by city governments and their potential positive effects on a number of urban life facets we opt to study and quantify the value of these systems. We focus on a specific aspect of this value and use evidence from the real estate market in the city of Pittsburgh to analyze the effect on dwellers' properties of the shared bike system installed in the city in June 2015. We use quasi-experimental techniques and find that the shared bike system led to an increase in the housing prices (both sales and rental prices in the zip codes where shared bike stations were installed. We further bring into the light potential negative consequences of this impact (i.e., gentrification and discuss/propose two public policies that can exploit the impact of the system for the benefit of both the local government as well as the city dwellers.

  16. 1996 environmental monitoring report for the Bettis Atomic Power Laboratory, Pittsburgh Site

    1996-01-01

    The 1996 results for the Bettis-Pittsburgh radiological and non-radiological environmental monitoring programs are presented. The primary mission of the Bettis Laboratory has been directed toward the design, development, testing, and operation of nuclear reactor propulsion plants for naval surface and submarine vessels. The results obtained from the monitoring programs demonstrate that the existing procedures ensured that releases to the environment during 1996 were in accordance with applicable federal, state, county, and local regulations. Evaluation of the environmental data indicated that the current operations at the Site continue to have no adverse effect on the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Site operations demonstrated that the dose received by any member of the public was well below the most restrictive dose limits established by the Environmental Protection Agency, the Nuclear Regulatory Commission and the US Department of Energy. A risk assessment of potentially exposed populations to chemical residues in the environment at the Site demonstrated that these residues do not pose any significant health risk

  17. 1996 environmental monitoring report for the Bettis Atomic Power Laboratory, Pittsburgh Site

    NONE

    1996-12-31

    The 1996 results for the Bettis-Pittsburgh radiological and non-radiological environmental monitoring programs are presented. The primary mission of the Bettis Laboratory has been directed toward the design, development, testing, and operation of nuclear reactor propulsion plants for naval surface and submarine vessels. The results obtained from the monitoring programs demonstrate that the existing procedures ensured that releases to the environment during 1996 were in accordance with applicable federal, state, county, and local regulations. Evaluation of the environmental data indicated that the current operations at the Site continue to have no adverse effect on the quality of the environment. A conservative assessment of radiation exposure to the general public as a result of Site operations demonstrated that the dose received by any member of the public was well below the most restrictive dose limits established by the Environmental Protection Agency, the Nuclear Regulatory Commission and the US Department of Energy. A risk assessment of potentially exposed populations to chemical residues in the environment at the Site demonstrated that these residues do not pose any significant health risk.

  18. Vulnerability studies and integrated assessments for hazard risk reduction in Pittsburgh, PA (Invited)

    Klima, K.

    2013-12-01

    Today's environmental problems stretch beyond the bounds of most academic disciplines, and thus solutions require an interdisciplinary approach. For instance, the scientific consensus is changes in the frequency and severity of many types of extreme weather events are increasing (IPCC 2012). Yet despite our efforts to reduce greenhouse gases, we continue to experience severe weather events such as Superstorm Sandy, record heat and blizzards, and droughts. These natural hazards, combined with increased vulnerability and exposure, result in longer-lasting disruptions to critical infrastructure and business continuity throughout the world. In order to protect both our lives and the economy, we must think beyond the bounds of any one discipline to include an integrated assessment of relevant work. In the wake of recent events, New York City, Washington, DC, Chicago, and a myriad of other cities have turned to their academic powerhouses for assistance in better understanding their vulnerabilities. This talk will share a case study of the state of integrated assessments and vulnerability studies of energy, transportation, water, real estate, and other main sectors in Pittsburgh, PA. Then the talk will use integrated assessment models and other vulnerability studies to create coordinated sets of climate projections for use by the many public agencies and private-sector organizations in the region.

  19. Investment Avenues

    Jain, Priyanka

    2012-11-01

    Investors are a heterogeneous group, they may be large or small, rich or poor, expert or lay man and not all investors need equal degree of protection (Mayya, 1996). An investor has three objectives while investing his money, namely safety of invested money, liquidity position of invested money and return on investment. The return on investment may further be divided into capital gain and the rate of return on investment as interest or dividend. Among all investment options available, securities are considered the most challenging as well as rewarding. Securities include shares, debentures, derivatives, units of mutual funds, Government securities etc. An investor may be an individual or corporate legal entity investing funds with a view to derive maximum economic advantage from investment such as rate of return, capital appreciation, marketability, tax advantage and convenience of investment.The Capital market facilitates mobilization of savings of individuals and pools them into reservoir of capital which can be used for the economic development of a country. An efficient capital market is essential for raising capital by the corporate sector of the economy and for the protection of the interest of investors in corporate securities. There arises a need to strike a balance between raising of capital for economic development on one side and protection of investors on the other. Unless the interests of investors are protected, raising of capital, by corporates is not possible. Like, the primary objective of a senior citizenís asset allocation is the generation of regular income.

  20. Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting.

    Pansieri, Jonathan; Plissonneau, Marie; Stransky-Heilkron, Nathalie; Dumoulin, Mireille; Heinrich-Balard, Laurence; Rivory, Pascaline; Morfin, Jean-François; Toth, Eva; Saraiva, Maria Joao; Allémann, Eric; Tillement, Olivier; Forge, Vincent; Lux, François; Marquette, Christel

    2017-07-01

    Gadolinium-based nanoparticles were functionalized with either the Pittsburgh compound B or a nanobody (B10AP) in order to create multimodal tools for an early diagnosis of amyloidoses. The ability of the functionalized nanoparticles to target amyloid fibrils made of β-amyloid peptide, amylin or Val30Met-mutated transthyretin formed in vitro or from pathological tissues was investigated by a range of spectroscopic and biophysics techniques including fluorescence microscopy. Nanoparticles functionalized by both probes efficiently interacted with the three types of amyloid fibrils, with K D values in 10 micromolar and 10 nanomolar range for, respectively, Pittsburgh compound B and B10AP nanoparticles. Moreover, they allowed the detection of amyloid deposits on pathological tissues. Such functionalized nanoparticles could represent promising flexible and multimodal imaging tools for the early diagnostic of amyloid diseases, in other words, Alzheimer's disease, Type 2 diabetes mellitus and the familial amyloidotic polyneuropathy.

  1. Male mental health problems, psychopathy, and personality traits: key findings from the first 14 years of the Pittsburgh Youth Study.

    Loeber, R; Farrington, D P; Stouthamer-Loeber, M; Moffitt, T E; Caspi, A; Lynam, D

    2001-12-01

    This paper reviews key findings on juvenile mental health problems in boys, psychopathy, and personality traits, obtained in the first 14 years of studies using data from the Pittsburgh Youth Study. This is a study of 3 samples, each of about 500 boys initially randomly drawn from boys in the 1st, 4th, and 7th grades of public schools in Pittsburgh. The boys have been followed regularly, initially each half year, and later at yearly intervals. Currently, the oldest boys are about 25 years old, whereas the youngest boys are about 19. Findings are presented on the prevalence and interrelation of disruptive behaviors, ADHD, and depressed mood. Results concerning risk factors for these outcomes are reviewed. Psychological factors such as psychopathy, impulsivity, and personality are described. The paper closes with findings on service delivery of boys with mental health problems.

  2. Innovation in hydroelectric power plant design in early twentieth century. Casto Fernández-Shaw's Engineering Architecture in La Jándula dam

    A. B. Berrocal Menárguez

    2017-09-01

    Full Text Available The power plant location in the first hydroelectrial dams was a relevant issue at the end of XIX century and early XX. Different solutions were tried, some of them with very interesting aesthetics results and hydraulic and structural implications. Such is the case of La Jándula dam, inaugurated in 1930, that includes the power station inside the dam. This article examines the possible national and international inspirations of this singular solution, corroborating the hypothesis of its unprecedented nature. The collaboration of the architect Casto Fernández-Shaw in the design and integration of the engine room was decisive, because it achieved a result of an aesthetic quality and formal expressiveness unprecedented in a work of hydraulic engineering, as well as the birth of a style Shaw himself defined as architectural engineering.

  3. Building America Case Study: High-Velocity Small-Diameter Duct System, Pittsburgh, Pennsylvania

    2017-04-01

    This study tests the performance of a variable airflow small-diameter duct heating, ventilation, and air conditioning (HVAC) system in a new construction unoccupied low-load test house in Pittsburgh, Pennsylvania. The duct system was installed entirely in conditioned space and was operated from the winter through summer seasons. Measurements were collected on the in-room temperatures and energy consumed by the air handler and heat pump unit. Operation modes with three different volumes of airflow were compared to determine the ideal airflow scenario that maximizes room-to-room thermal uniformity while minimizing fan energy consumption. Black felt infrared imagery was used as a measure of diffuser throw and in-room air mixing. Measured results indicate the small-diameter, high velocity airflow system can provide comfort under some conditions. Solar heat gains resulted in southern rooms drifting beyond acceptable temperature limits. Insufficient airflow to some bedrooms also resulted in periods of potential discomfort. Homebuilders or HVAC contractors can use these results to assess whether this space conditioning strategy is an attractive alternative to a traditional duct system. The team performed a cost analysis of two duct system configurations: (1) a conventional diameter and velocity duct system, and (2) the small-diameter duct system. This work applies to both new and retrofit homes that have achieved a low heating and cooling density either by energy conservation or by operation in a mild climate with few heating or cooling degree days. Guidance is provided on cost trade-offs between the conventional duct system and the small-diameter duct system.

  4. Description of interview data regarding Pittsburgh and confluence toxic chemical accidents

    Rogers, G.O.; Shumpert, B.L.; Sorensen, J.H.

    1990-11-01

    Evacuation is the protective action most often recommended in response to chemical releases in the United States. The appropriateness of a decision to evacuate depends on whether the affected areas can be cleared of residents before it is contaminated by the chemical release. In determining whether an evacuation can be completed in time, emergency officials must consider both technical and behavioral aspects. The technical components can be readily conceived and quantified. In contrast, the behavioral components are much more abstract and more difficult to estimate. This report summarizes the univariate analysis of responses to surveys conducted in two communities where evacuation was recommended following train derailments involving hazardous chemicals. The surveys were designed to identify the actions taken by residents upon receiving the emergency warning; determine when people received the warning, decided to take action, and implemented the action; and ascertain factors that might explain the nature and timing of their actions. The surveys were conducted in the Bloomfield section of Pittsburgh, Pennsylvania, and in the town of Confluence, Pennsylvania. The study confirms that compliance with an emergency warning to evacuate varies and that potentially dangerous delays can be expected. Significant differences were noted, however, in the rate and speed of compliance in the two communities. The surveys provide information on several factors that may be useful in determining the reasons for differences in the responses from the two communities as well as differences among individual respondents. Such factors include the time of day when the accident occurred, where the respondent was at the time, whether the family was together, previous disaster experience, pet ownership, the content of the warning message, and demographic characteristics. 4 refs., 4 figs., 18 tabs.

  5. Reduced binding of Pittsburgh Compound-B in areas of white matter hyperintensities

    A.E. Goodheart

    2015-01-01

    Full Text Available The amyloid imaging agent, Pittsburgh Compound-B, binds with high affinity to β-amyloid (Aβ in the brain, and it is well established that PiB also shows non-specific retention in white matter (WM. However, little is known about retention of PiB in areas of white matter hyperintensities (WMH, abnormalities commonly seen in older adults. Further, it is hypothesized that WMH are related to both cognitive dysfunction and Aβ deposition. The goal of the present study was to explore PiB retention in both normal-appearing WM (NAWM and WMH in a group of elderly, cognitively normal individuals. In a group of cognitively normal elderly (n = 64; 86.5 ± 2.6 years two analyses were applied: (1 ROIs were placed over periventricular areas in which WMH caps are commonly seen on all subjects, regardless of WMH burden or size. (2 Subject-specific maps of NAWM and WMH were co-registered with the PiB-PET images and mean SUVR values were calculated in these NAWM and WMH maps. PiB retention was significantly reduced in the ROIs of subjects with high WMH compared to subjects with low WMH. Additionally, in subjects with high WMH, there was significantly lower PiB retention in subject-specific maps of WMH compared to NAWM, which was not observed in subjects with low WMH, likely because of the small size of WMH maps in this group. These data suggest that WM in areas of WMH binds PiB less effectively than does normal WM. Further exploration of this phenomenon may lead to insights about the molecular basis of the non-specific retention of amyloid tracers in white matter.

  6. Pittsburgh compound-B PET white matter imaging and cognitive function in late multiple sclerosis.

    Zeydan, Burcu; Lowe, Val J; Schwarz, Christopher G; Przybelski, Scott A; Tosakulwong, Nirubol; Zuk, Samantha M; Senjem, Matthew L; Gunter, Jeffrey L; Roberts, Rosebud O; Mielke, Michelle M; Benarroch, Eduardo E; Rodriguez, Moses; Machulda, Mary M; Lesnick, Timothy G; Knopman, David S; Petersen, Ronald C; Jack, Clifford R; Kantarci, Kejal; Kantarci, Orhun H

    2018-05-01

    There is growing interest in white matter (WM) imaging with positron emission tomography (PET). We studied the association of cognitive function in late multiple sclerosis (MS) with cortical and WM Pittsburgh compound-B PET (PiB-PET) binding. In the population-based Mayo Clinic Study of Aging, 24 of 4869 participants had MS (12 underwent PiB-PET). Controls were age and sex matched (5:1). We used automated or semi-automated processing for quantitative image analyses and conditional logistic regression for group differences. MS patients had lower memory ( p = 0.03) and language ( p = 0.02) performance; smaller thalamic volumes ( p = 0.003); and thinner temporal ( p = 0.001) and frontal ( p = 0.045) cortices on magnetic resonance imaging (MRI) than controls. There was no difference in global cortical PiB standardized uptake value ratios between MS and controls ( p = 0.35). PiB uptake was lower in areas of WM hyperintensities compared to normal-appearing white matter (NAWM) in MS ( p = 0.0002). Reduced PiB uptake in both the areas of WM hyperintensities ( r = 0.65; p = 0.02) and NAWM ( r = 0.69; p = 0.01) was associated with decreased visuospatial performance in MS. PiB uptake in the cortex in late MS is not different from normal age-matched controls. PiB uptake in the WM in late MS may be a marker of the large network structures' integrity such as those involved in visuospatial performance.

  7. Pittsburgh compound B (PiB) PET imaging of meningioma and other intracranial tumors.

    Johnson, Derek R; Hunt, Christopher H; Nathan, Mark A; Parisi, Joseph E; Boeve, Bradley F; Murray, Melissa E; Knopman, David S; Jack, Clifford R; Petersen, Ronald C; Lowe, Val J; Johnson, Geoffrey B

    2018-01-01

    Meningiomas are the most common intracranial tumors. Diagnosis by MRI is generally straightforward, but lack of imaging specificity can present a diagnostic dilemma, particularly in patients with cancer. We report our experience with meningioma identification on Pittsburgh compound B (PiB) PET/CT. Patients who underwent PiB PET/CT from 2006 to 2015 were reviewed to identify those with intracranial tumors. Tumor types were classified by MR appearance, or by pathology when available. Maximum standardized uptake value (SUVmax) measurements of tumor PiB activity were compared across tumor types. 2472 patients underwent PiB PET/CT in the period of interest; 45 patients (1.8%) had probable or definite intracranial tumor. Tumor types were meningioma (29/45, 64%), vestibular schwannoma (7/45, 16%), pituitary macroadenoma (4/45, 9%), metastatic disease (2/45, 4%), and others (3/45, 7%). In patients with meningioma, the mean lesion SUVmax was 2.05 (SD 1.37), versus 1.00 (SD 0.42) in patients with non-meningioma tumors (p < 0.01). A receiver operating curve was created for lesion:cerebellum SUVmax ratio, with an area under the curve of 0.91 for a value of 1.68. At or above this ratio, specificity for meningioma was 100% (95% CI 79-100%) and sensitivity was 76% (95% CI 57-90%). PiB PET activity within an intracranial tumor is a highly specific and reasonably sensitive marker of meningioma. Further prospective evaluation is warranted to validate this result as well as to assess the performance of commercially available beta-amyloid radiotracers in meningioma identification.

  8. Investigation and visualization of liquid–liquid flow in a vertically mounted Hele-Shaw cell: flow regimes, velocity and shape of droplets

    Shad, S; Gates, I D; Maini, B B

    2009-01-01

    The motion and shape of a liquid drop flowing within a continuous, conveying liquid phase in a vertical Hele-Shaw cell were investigated experimentally. The continuous phase was more viscous and wetted the bounding walls of the Hele-Shaw cell. The gap between the Hele-Shaw plates was set equal to 0.0226 cm. Four different flow regimes were observed: (a) small-droplet flow, (b) elongated-droplet flow, (c) churn flow and (d) channel flow. At low capillary number, that is, when capillary forces are larger than viscous forces, the droplet shape was irregular and changed with time and distance, and it moved with lower velocity than that of the conveying phase. At higher capillary number, several different shapes of stabilized elongated and flattened drops were observed. In contrast to gas–liquid systems, the velocities of droplets are higher than that of conveying liquid. New correlations derived from dimensionless analysis and fitted to the experimental data were generated to predict the elongated-drop velocity and aspect ratio

  9. Investigation and visualization of liquid-liquid flow in a vertically mounted Hele-Shaw cell: flow regimes, velocity and shape of droplets

    Shad, S.; Gates, I. D.; Maini, B. B.

    2009-11-01

    The motion and shape of a liquid drop flowing within a continuous, conveying liquid phase in a vertical Hele-Shaw cell were investigated experimentally. The continuous phase was more viscous and wetted the bounding walls of the Hele-Shaw cell. The gap between the Hele-Shaw plates was set equal to 0.0226 cm. Four different flow regimes were observed: (a) small-droplet flow, (b) elongated-droplet flow, (c) churn flow and (d) channel flow. At low capillary number, that is, when capillary forces are larger than viscous forces, the droplet shape was irregular and changed with time and distance, and it moved with lower velocity than that of the conveying phase. At higher capillary number, several different shapes of stabilized elongated and flattened drops were observed. In contrast to gas-liquid systems, the velocities of droplets are higher than that of conveying liquid. New correlations derived from dimensionless analysis and fitted to the experimental data were generated to predict the elongated-drop velocity and aspect ratio.

  10. An avenue of eddies: Quantifying the biophysical properties of mesoscale eddies in the Tasman Sea

    Everett, J. D.; Baird, M. E.; Oke, P. R.; Suthers, I. M.

    2012-08-01

    The Tasman Sea is unique - characterised by a strong seasonal western boundary current that breaks down into a complicated field of mesoscale eddies almost immediately after separating from the coast. Through a 16-year analysis of Tasman Sea eddies, we identify a region along the southeast Australian coast which we name ‘Eddy Avenue’ where eddies have higher sea level anomalies, faster rotation and greater sea surface temperature and chlorophyll a anomalies. The density of cyclonic and anticyclonic eddies within Eddy Avenue is 23% and 16% higher respectively than the broader Tasman Sea. We find that Eddy Avenue cyclonic and anticyclonic eddies have more strongly differentiated biological properties than those of the broader Tasman Sea, as a result of larger anticyclonic eddies formed from Coral Sea water depressing chl. a concentrations, and for coastal cyclonic eddies due to the entrainment of nutrient-rich shelf waters. Cyclonic eddies within Eddy Avenue have almost double the chlorophyll a (0.35 mg m-3) of anticyclonic eddies (0.18 mg m-3). The average chlorophyll a concentration for cyclonic eddies is 16% higher in Eddy Avenue and 28% lower for anticyclonic eddies when compared to the Tasman Sea. With a strengthening East Australian Current, the propagation of these eddies will have significant implications for heat transport and the entrainment and connectivity of plankton and larval fish populations.

  11. Metals in soils adjacent to avenues of highly dense traffic of Sao Paulo city, Brazil

    Ticianelli, Regina B.; Ribeiro, Andreza P.; Figueiredo, Ana M.G.; Nammoura-Neto, Georges M.; Silva, Nathalia C.

    2009-01-01

    Sao Paulo is the largest city in Brazil with about 19 millions of inhabitants in the metropolitan area, more than 8 million motor vehicles and strong industrial activity at the metropolitan region, which are responsible for increasing pollution in the region. Nevertheless, there is little information on metal contents in the metropolitan region soils, which would be very useful as a fingerprint of the environmental pollution. The present study aimed to determine As, Ba, Co, Cr, Sb and Zn concentrations in soils adjacent to avenues of highly dense traffic downtown Sao Paulo city: Consolacao/Reboucas Avenues; 23 de Maio Avenue and Tiradentes Avenue, to assess their possible sources and potential environmental impact. The analytical technique employed was Instrumental Neutron Activation Analysis (INAA). The results show metal concentration levels higher than the values reference values for soils of Sao Paulo, according to the Environmental Protection Agency of the State Sao Paulo (CETESB) guidelines. As, Ba and Zn showed concentration levels above the Intervention Values in some points, indicating direct or indirect potential risks to human health. The traffic related element Ba, Sb and Zn presented concentrations above the Prevention Values in points with high density traffic and may be associated to vehicular emissions. (author)

  12. New avenues for treating emotional memory disorders : Towards a reconsolidation intervention for posttraumatic stress disorder

    Kindt, M.; van Emmerik, A.

    The discovery that fear memories may change upon retrieval, a process referred to as memory reconsolidation, opened avenues to develop a revolutionary new treatment for emotional memory disorders. Reconsolidation is a two-phase process in which retrieval of a memory initiates a transient period of

  13. 78 FR 11142 - Connor Hayden Kraegel, 19917 Spurrier Avenue, Poolesville, MD 20837; Order Denying Export Privileges

    2013-02-15

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Connor Hayden Kraegel, 19917 Spurrier... Court, District of Maryland, Connor Hayden Kraegel (``Kraegel'') was convicted of violating Section 38... Hayden Kraegel, with a last known address at: 19917 Spurrier Avenue, Poolesville, MD 20837, and when...

  14. Improving Critical Thinking Skills Using Learning Model Logan Avenue Problem Solving (LAPS)-Heuristic

    Anggrianto, Desi; Churiyah, Madziatul; Arief, Mohammad

    2016-01-01

    This research was conducted in order to know the effect of Logan Avenue Problem Solving (LAPS)-Heuristic learning model towards critical thinking skills of students of class X Office Administration (APK) in SMK Negeri 1 Ngawi, East Java, Indonesia on material curve and equilibrium of demand and supply, subject Introduction to Economics and…

  15. The urban land debate in the global South : New avenues for research

    Steel, Griet|info:eu-repo/dai/nl/304349828; van Noorloos, Femke|info:eu-repo/dai/nl/342952706; Klaufus, Christien

    2017-01-01

    The global ‘land grab’ debate is going urban and needs a specific conceptual framework to analyze the diverse modalities through which land commodification and speculation are transforming cities across the globe. This article identifies new avenues for research on urban land issues by drawing on an

  16. The urban land debate in the global South : New avenues for research

    Steel, G.; van Noorloos, F.; Klaufus, C.

    The global ‘land grab’ debate is going urban and needs a specific conceptual framework to analyze the diverse modalities through which land commodification and speculation are transforming cities across the globe. This article identifies new avenues for research on urban land issues by drawing on an

  17. A well-posed numerical method to track isolated conformal map singularities in Hele-Shaw flow

    Baker, G.; Siegel, M.; Tanveer, S.

    1995-01-01

    We present a new numerical method for calculating an evolving 2D Hele-Shaw interface when surface tension effects are neglected. In the case where the flow is directed from the less viscous fluid into the more viscous fluid, the motion of the interface is ill-posed; small deviations in the initial condition will produce significant changes in the ensuing motion. The situation is disastrous for numerical computation, as small roundoff errors can quickly lead to large inaccuracies in the computed solution. Our method of computation is most easily formulated using a conformal map from the fluid domain into a unit disk. The method relies on analytically continuing the initial data and equations of motion into the region exterior to the disk, where the evolution problem becomes well-posed. The equations are then numerically solved in the extended domain. The presence of singularities in the conformal map outside of the disk introduces specific structures along the fluid interface. Our method can explicitly track the location of isolated pole and branch point singularities, allowing us to draw connections between the development of interfacial patterns and the motion of singularities as they approach the unit disk. In particular, we are able to relate physical features such as finger shape, side-branch formation, and competition between fingers to the nature and location of the singularities. The usefulness of this method in studying the formation of topological singularities (self-intersections of the interface) is also pointed out. 47 refs., 10 figs., 1 tab

  18. Effects of testosterone on contractile properties of sexually dimorphic forelimb muscles in male bullfrogs (Rana catesbeiana, Shaw 1802

    Aaron R. Kampe

    2013-07-01

    This study examined the effects of testosterone (T on the contractile properties of two sexually dimorphic forelimb muscles and one non-dimorphic muscle in male bullfrogs (Rana catesbeiana, Shaw 1802. The dimorphic muscles in castrated males with testosterone replacement (T+ achieved higher forces and lower fatigability than did castrated males without replaced testosterone (T0 males, but the magnitude of the differences was low and many of the pair-wise comparisons of each muscle property were not statistically significant. However, when taken as a whole, the means of seven contractile properties varied in the directions expected of masculine values in T+ animals in the sexually dimorphic muscles. Moreover, these data, compared with previous data on male and female bullfrogs, show that values for T+ males are similar to normal males and are significantly different from females. The T0 males tended to be intermediate in character between T+ males and females, generally retaining masculine values. This suggests that the exposure of young males to T in their first breeding season produces a masculinizing effect on the sexually dimorphic muscles that is not reversed between breeding seasons when T levels are low. The relatively minor differences in contractile properties between T+ and T0 males may indicate that as circulating T levels rise during breeding season in normal males, contractile properties can be enhanced rapidly to maximal functional levels for breeding success.

  19. Growth-direction dependence of steady-state Saffman-Taylor flow in an anisotropic Hele-Shaw cell

    McCloud, K.V.; Maher, J.V.

    1996-01-01

    Selection of steady-state fingers has been measured in a Hele-Shaw cell perturbed by having a square lattice etched onto one of the plates. Flows at different orientations θ between the direction of flow and the lattice axes have been studied, in a wide range of observable tip velocities where the perturbation was made microscopic in the sense that the capillary length of the flow was much greater than the etched lattice cell size. The full range of dynamically interesting angles for the square lattice was examined, and above a threshold, the microscopic perturbation always results in wider fingers than are selected in the unperturbed case. There is some dependence of the width of the fingers on the orientation of the flow, with fingers at θ=0 degree being the widest with respect to the unperturbed fingers, and fingers at 45 degree being the least wide, although still wider than the unperturbed fingers. All observed solutions are symmetric, centered in the channel, and have the relation between tip-curvature and finger width expected of members of the Saffman-Taylor family of solutions. Selected solutions narrow again at tip velocities where the perturbation can no longer be considered microscopic. copyright 1996 The American Physical Society

  20. Growth of fingers at an unstable diffusing interface in a porous medium or hele-shaw cell

    Wooding, R A

    1969-11-27

    Waves at an unstable horizontal interface, between 2 fluids moving vertically through a saturated porous medium, are observed to grow rapidly to become fingers (i.e., the amplitude greatly exceeds the wavelength). For a diffusing interface, in experiments using a Hele-Shaw cell, the mean amplitude taken over many fingers grows approx. as (time)U2D, followed by a transition to a growth proportional to time. Correspondingly, the mean wave number decreases approx. as (time)U-1/2D. Because of the rapid increase in amplitude, longitudinal dispersion ultimately becomes negligible relative to wave growth. To represent the observed quantities at large time, the transport equation is suitably weighted and averaged over the horizontal plane. Hyperbolic equations result, and the ascending and descending zones containing the fronts of the fingers are replaced by discontinuities. These averaged equations form an open set, but closure is achieved by assuming a law for the mean wave number based on similarity. (22 refs.)

  1. Paleomagnetic intensity of Aso pyroclastic flows: Additional results with LTD-DHT Shaw method, Thellier method with pTRM-tail check

    Maruuchi, T.; Shibuya, H.

    2009-12-01

    For the sake to calibrate the absolute value of the ’relative paleointensity variation curve’ drawn from sediment cores, Takai et al. (2002) proposed to use pyroclastic flows co-bearing with wide spread tephras. The pyroclastic flows prepare volcanic rocks with TRM, which let us determine absolute paleointensity, and the tephras prepare the correlation with sediment stratigraphy. While 4 out of 6 pyroclastic flows are consistent with Sint-800 paleointensity variation curve, two flows, Aso-2 and Aso-4, show weaker and stronger than Sint-800 beyond the error, respectively. We revisited the paleointensity study of Aso pyroclastic flows, adding LTD- DHT Shaw method, the pTRM-tail check in Thellier experiment, and LTD-DHT Shaw method by using volcanic glasses. We prepared 11 specimens from 3 sites of Aso-1 welded tuff for LTD-DHT Shaw method experiments, and obtained 6 paleointensities satisfied a set of strict criteria. They yield an average paleointensity of 21.3±5.8uT, which is smaller than 31.0±3.4uT provided by Takai et al. (2002). For Aso-2 welded tuff, 11 samples from 3 sites were submitted to Thellier experiments, and 6 passed a set of pretty stringent criteria including pTRM-tail check, which is not performed by Takai et al. (2002). They give an average paleointensity of 20.2±1.5uT, which is virtually identical to 20.2±1.0uT (27 samples) given by Takai et al. (2002). Although the success rate was not good in LTD-DHT Shaw method, 2 out of 12 specimens passed the criteria, and gave 25.8±3.4uT, which is consistent with Takai et al. (2002). In addition, we obtained a reliable paleointensity from a volcanic glass in LTD-DHT Shaw method, it gives a paleointensity of 23.6 uT. It is also consitent with Takai et al. (2002). For Aso-3 welded tuff, we performed only LTD-DHT Shaw method for one specimen from one site yet. It gives a paleointensity of 43.0uT, which is higher than 31.8±3.6uT given by Takai et al. (2002). Eight sites were set for Aso-4 welded tuff

  2. Sino-U.S. partnerships in research, education, and patient care: The experience of the University of Pittsburgh and UPMC.

    Levine, Arthur S; McDonald, Margaret C; Bogosta, Charles E

    2017-10-01

    In 2011, the University of Pittsburgh School of Medicine (UPSOM) and Tsinghua University formed a partnership to further the education of Tsinghua medical students. These students come to UPSOM as visiting research scholars for two years of their eight-year MD curriculum. During this time, the students, who have completed four years at Tsinghua, work full-time in medical school laboratories and research programs of their choice, essentially functioning as graduate students. In their first two months in Pittsburgh, the scholars have a one-week orientation to biomedical research, followed by two-week rotations in four labs selected on the basis of the scholars' scientific interests, after which they choose one of these labs for the remainder of the two years. Selected labs may be in basic science departments, basic science divisions of clinical departments, or specialized centers that focus on approaches like simulation and modeling. The Tsinghua students also have a brief exposure to clinical medicine. UPSOM has also formed a similar partnership with Central South University Xiangya School of Medicine in Changsha, Hunan Province. The Xiangya students come to UPSOM for two years of research training after their sixth year and, thus, unlike the Tsinghua students, have already completed their clinical rotations. UPSOM faculty members have also paved the way for UPMC (University of Pittsburgh Medical Center), UPSOM's clinical partner, to engage with clinical centers in China. Major relationships involving advisory, training, managerial, and/or equity roles exist with Xiangya International Medical Center, KingMED Diagnostics, First Chengmei Medical Industry Group, and Macare Women's Hospital. Both UPSOM and UPMC are actively exploring other clinical and academic opportunities in China.

  3. Simplified Space Conditioning in Low-Load Homes: Results from Pittsburgh, Pennsylvania, New Construction Unoccupied Test House

    Poerschke, A.; Stecher, D.

    2014-06-01

    Field testing was performed in a new construction unoccupied test house in Pittsburgh, Pennsylvania. Four air-based heating, ventilation, and air conditioning distribution systems--a typical airflow ducted system to the bedrooms, a low airflow ducted system to the bedrooms, a system with transfer fans to the bedrooms, and a system with no ductwork to the bedrooms--were evaluated during heating, cooling, and midseason conditions. The relative ability of each system was assessed with respect to relevant Air Conditioning Contractors of America and ASHRAE standards for house temperature uniformity and stability, respectively.

  4. Simplified Space Conditioning in Low-Load Homes: Results from Pittsburgh, Pennsylvania, New Construction Unoccupied Test House

    Poerschke, Andrew [IBACOS, Inc., Pittsburgh, PA (United States); Stecher, Dave [IBACOS, Inc., Pittsburgh, PA (United States)

    2014-06-01

    Field testing was performed in a new construction unoccupied test house in Pittsburgh, PA. Four air-based heating, ventilation, and air conditioning distribution systems—a typical airflow ducted system to the bedrooms, a low airflow ducted system to the bedrooms, a system with transfer fans to the bedrooms, and a system with no ductwork to the bedrooms—were evaluated during heating, cooling, and midseason conditions. The relative ability of each system was assessed with respect to relevant Air Conditioning Contractors of America and ASHRAE standards for house temperature uniformity and stability, respectively.

  5. New Avenues for History in Mathematics Education: Mathematical Competencies and Anchoring

    Jankvist, U. T.; Kjeldsen, T. H.

    2011-01-01

    . The first scenario occurs when history is used as a ‘tool’ for the learning and teaching of mathematics, the second when history of mathematics as a ‘goal’ is pursued as an integral part of mathematics education. We introduce a multiple-perspective approach to history, and suggest that research on history......The paper addresses the apparent lack of impact of ‘history in mathematics education’ in mathematics education research in general, and proposes new avenues for research. We identify two general scenarios of integrating history in mathematics education that each gives rise to different problems...... in mathematics education follows one of two different avenues in dealing with these scenarios. The first is to focus on students’ development of mathematical competencies when history is used a tool for the learning of curriculum-dictated mathematical in-issues. A framework for this is described. Secondly, when...

  6. Phytochemical screening, total phenolics and antioxidant activities of bark and leaf extracts of Goniothalamus velutinus (Airy Shaw from Brunei Darussalam

    Erum Iqbal

    2015-07-01

    Full Text Available Goniothalamus velutinus Airy Shaw belongs to the family Annonaceae which is known to have anticancer, antitumor and many other bioactivities. Natives of Sabah and Sarawak use root decoction of G. velutinus for the treatment of headache and food poisoning while the bark was used as a mosquito repellent. Bark and leaf extracts of this plant, obtained from Brunei Darussalam, were tested for phytochemical and antioxidant activities. Phytochemical screening of plant extracts revealed the presence of alkaloids, steroids, terpenoids and cardiac glycosides. Quantitative determination of total phenolics, total flavonoids, and various in vitro antioxidant activities (DPPH, ABTS and FRAP of methanolic extract was carried out using colorimetric methods. The total phenolic content, expressed as mg of gallic acid equivalent (GAE per gram of extract, was found to be 68 mg GAE/g and 78 mg GAE/g for bark and leaves respectively. The radical scavenging activity measurement, expressed in terms of EC50 (effective concentration of extract in μg/mL that reduces DPPH absorbance to 50% as compared to negative control, for leaf and bark extracts was found to be 155 μg/mL and 204 μg/mL respectively. Standards trolox and ascorbic acid show EC50 value of 5 μg/mL and 4 μg/mL respectively. Trolox equivalent antioxidant capacity (TEAC was measured using the ABTS and FRAP method. Result for bark and leaf extracts was 79 mg and 106 mg trolox equivalent (TE/g respectively for the ABTS method. For FRAP assay, results for bark and leaf extracts were 80 and 89 mg TE/g respectively.

  7. Reconversion(s territoriale(s sur l’avenue de Kurtuluş

    Cilia Martin

    2011-07-01

    Full Text Available Le quartier de Kurtuluş à Istanbul, héritier de l’ancien village de Tatavla, se forme et se développe jusqu’au milieu du XXe siècle. A partir des années 1950, le départ des minoritaires rum, jusque là quasi majoritaires, et l’arrivée des migrants anatoliens provoquent des ruptures démographiques considérables. Ces mobilités suscitent une diversité de modes territoriaux et produisent de nouvelles centralités, observables aussi par le bais du commerce et récemment à travers les stratégies mémorielles qui réédifient le passé rum du quartier. Enfin, ces territorialités participent à la recomposition du quartier et seront analysées à l’échelle d’une avenue phare, l’avenue de Kurtuluş.The neighborhood of Kurtuluş, heritage of the ancient village of Tatavla, was formed and developed till the mid of the 20th century. From 1950, along with the departure of the Rum minorities, which were considered till that time as quasi majorities, and with the arrival of Anatolian migrants, considerable demographical ruptures were provoked. Thoses mobilities create a diversity of territorial modes and give birth to new centralities, seen also throughout the commerce and recently from within the memorial strategies which rebuild the rum past of the neighborhood. Finally, those territorialities participate to the recomposition of the neigborhood and will be analysed through the scale of a headlight avenue, the avenue of Kurtuluş.

  8. The Revival of Memory: Gardens and Avenues of Remembrance. Early Results of a Research in Abruzzo

    Aldo Giorgio Pezzi

    2014-06-01

    Full Text Available The forthcoming centenary of the Great War (1914-1918 can be considered an important occasion to focus attention on the subject of memorials for the fallen in the War. Immediately after the War, this topic was considered so relevant that in each municipality of Italy, Gardens and Avenues of Remembrance were realized and soon became places of memory, characterized by strong values of identity, history and landscape. In these places, usually correspondent to the number of fallen in that neighbourhood and located in urban or peripheral areas, nature and anthropic elements coexisted. For their importance, from 1926 these places have been included among the National Monuments. After the Second World War, avenues and gardens, as well as toponyms, were gradually forgotten and, in many cases, radically transformed. Due to a form of damnatio memoriae, which locations considered symbols of past governments have had to pay, these places have been changed, radically transforming also their authentic significance. A century on, it is important to start a programme for protection and enhancement of this historic heritage (classification at a regional and national scale, measurements, archival research, definition of guide lines for conservation. The essay also describes the early results of the classification of Gardens and Avenues of Remembrance in Abruzzo.

  9. 33 CFR 110.84 - Black Rock Channel opposite foot of Porter Avenue, Buffalo, N.Y.

    2010-07-01

    ... of Porter Avenue, Buffalo, N.Y. 110.84 Section 110.84 Navigation and Navigable Waters COAST GUARD... Channel opposite foot of Porter Avenue, Buffalo, N.Y. An area extending northwesterly between Black Rock... Triangulation Marker “N-5” on Bird Island Pier; thence southeasterly along the pier a distance of approximately...

  10. Creating a Methodology for Coordinating High-resolution Air Quality Improvement Map and Greenhouse Gas Mitigation Strategies in Pittsburgh City

    Shi, J.; Donahue, N. M.; Klima, K.; Blackhurst, M.

    2016-12-01

    In order to tradeoff global impacts of greenhouse gases with highly local impacts of conventional air pollution, researchers require a method to compare global and regional impacts. Unfortunately, we are not aware of a method that allows these to be compared, "apples-to-apples". In this research we propose a three-step model to compare possible city-wide actions to reduce greenhouse gases and conventional air pollutants. We focus on Pittsburgh, PA, a city with consistently poor air quality that is interested in reducing both greenhouse gases and conventional air pollutants. First, we use the 2013 Pittsburgh Greenhouse Gas Inventory to update the Blackhurst et al. model and conduct a greenhouse gas abatement potentials and implementation costs of proposed greenhouse gas reduction efforts. Second, we use field tests for PM2.5, NOx, SOx, organic carbon (OC) and elemental carbon (EC) data to inform a Land-use Regression Model for local air pollution at a 100m x 100m spatial level, which combined with a social cost of air pollution model (EASIUR) allows us to calculate economic social damages. Third, we combine these two models into a three-dimensional greenhouse gas cost abatement curve to understand the implementation costs and social benefits in terms of air quality improvement and greenhouse gas abatement for each potential intervention. We anticipated such results could provide policy-maker insights in green city development.

  11. Experimental particle physics at the University of Pittsburgh. Progress report, 1 November 1993--31 October 1994

    Engels, E. Jr.; Shepard, P.F.; Thompson, J.A.

    1994-05-01

    Task A involves the study of kaon decays. The overall physics focus of the current work is rare and semi-rare decays of the {phi} and the short-lived kaon, with an emphasis on those aspects needed in preparation for the proposed {Phi}-factory measurements of CPT violation. Another aspect of the rare kaon decay work is E865 at BNL, a search for K{sup +} yields {pi}{sup +}{mu}{sup +}e{sup {minus}}, a lepton number violating process. Pittsburgh`s E865 responsibilities are the design and construction of the Cerenkov counters. The major goals of task B are as follows: (1) the analysis of the E706 (direct photon production) data taken during the 1987--1988 and 1990--1991 target runs at Fermilab and (2) the continuation of work within SVXII group of the CDF collaboration. The CDF program involves a dedicated effort towards the design of the silicon vertex detector upgrade, SVXII.

  12. The effect of a crosslinking chemical reaction on pattern formation in viscous fingering of miscible fluids in a Hele-Shaw cell

    Bunton, Patrick H.; Tullier, Michael P.; Meiburg, Eckart; Pojman, John A.

    2017-10-01

    Viscous fingering can occur in fluid motion whenever a high mobility fluid displaces a low mobility fluid in a Darcy type flow. When the mobility difference is primarily attributable to viscosity (e.g., flow between the two horizontal plates of a Hele-Shaw cell), viscous fingering (VF) occurs, which is sometimes termed the Saffman-Taylor instability. Alternatively, in the presence of differences in density in a gravity field, buoyancy-driven convection can occur. These instabilities have been studied for decades, in part because of their many applications in pollutant dispersal, ocean currents, enhanced petroleum recovery, and so on. More recent interest has emerged regarding the effects of chemical reactions on fingering instabilities. As chemical reactions change the key flow parameters (densities, viscosities, and concentrations), they may have either a destabilizing or stabilizing effect on the flow. Hence, new flow patterns can emerge; moreover, one can then hope to gain some control over flow instabilities through reaction rates, flow rates, and reaction products. We report effects of chemical reactions on VF in a Hele-Shaw cell for a reactive step-growth cross-linking polymerization system. The cross-linked reaction product results in a non-monotonic viscosity profile at the interface, which affects flow stability. Furthermore, three-dimensional internal flows influence the long-term pattern that results.

  13. Teachers’ Working Conditions Amid Swedish School Choice Reform: Avenues for Further Research

    Karolina Åsa Parding

    2016-04-01

    Full Text Available Since the 1990s, governance changes, including customer choice agendas, have permeated the public sector and, consequently, welfare sector professionals’ work. One example is the education sector. The aim of this paper is to identify and discuss avenues for further research when it comes to teachers’ working conditions in the light of current choice agendas. This is accomplished by presenting an overview of previous studies on implications of the reforms for teachers’ working conditions. How are these conditions described in relation to the current school choice agenda in Sweden? What directions should be applied to increase knowledge of these conditions? We conclude by identifying some avenues for further research: the issues of organization of work, temporal and spatial dimensions of working conditions, and finally comparative studies of various forms, are suggested as warranting further investigation to highlight the diversified labor market in which teachers find themselves today.Keywords: Competition, governance change, privatization, professional work, school choice, Sweden, teaching profession, working conditions

  14. Spatial distribution of trace elements in topsoils adjacent to main avenues of Sao Paulo city, Brazil

    Ribeiro, Andreza P.; Figueiredo, Ana Maria G.; Nammoura-Neto, Georges M.; Silva, Natalia C.; Ticianelli, Regina B.; Camargo, Sonia P.; Enzweiler, Jacinta

    2009-01-01

    In the present study, the concentration and distribution of Ba, Cu, Mo, Pb, S, Zn and Zr in soils collected along two main avenues (Pinheiros River Highway and Tiete River Highway) with high traffic density in the metropolitan region of Sao Paulo, Brazil, are presented, and their possible sources are discussed. These elements are strongly considered as contaminants originated from vehicular emissions. The analytical technique employed was XRF. The data set was evaluated by a t test for independent samples (group: avenues) at a 0.05 significance level. According to t test, the average contents obtained from Pinheiros River Highways are significantly different than the Tiete River, except for Mo. Multivariate statistic approaches (Pearson Correlation, Cluster and Factorial Analysis - FA) were adopted for data treatment. FA identified two main factors which accounted for about 86% of the total variance. The behavior of Ba, Cu, Pb, S and Zn were explained by the Factor 1. This indicates that the elements may have similar sources, probably related to gas emissions escaping from the vehicle fuel system. Factor 2 included Mo and Zr, suggesting their origin in the sample soils may be associated with the deterioration process of some device in the vehicular engine system or may be associated with the chemical composition of the urban soil analyzed. (author)

  15. Why and How Political Science Can Contribute to Public Health? Proposals for Collaborative Research Avenues.

    Gagnon, France; Bergeron, Pierre; Clavier, Carole; Fafard, Patrick; Martin, Elisabeth; Blouin, Chantal

    2017-04-05

    Written by a group of political science researchers, this commentary focuses on the contributions of political science to public health and proposes research avenues to increase those contributions. Despite progress, the links between researchers from these two fields develop only slowly. Divergences between the approach of political science to public policy and the expectations that public health can have about the role of political science, are often seen as an obstacle to collaboration between experts in these two areas. Thus, promising and practical research avenues are proposed along with strategies to strengthen and develop them. Considering the interdisciplinary and intersectoral nature of population health, it is important to create a critical mass of researchers interested in the health of populations and in healthy public policy that can thrive working at the junction of political science and public health. © 2017 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  16. Constitutional Law--State Action--Hiring and Promotion Practices of Private University Receiving Public Funds Held State Action--Braden v. University of Pittsburgh.

    New York University Law Review, 1977

    1977-01-01

    In Braden vs University of Pittsburgh, a female professor filed suit against the University alleging sex discrimination in employment practices. The professor alleged that the school, which received state funds, was, in effect, a state actor and subject to constitutional restraints. This case and two relevant state action cases are discussed. (JMD)

  17. Development of a Coronary Heart Disease Risk Prediction Model for Type 1 Diabetes: The Pittsburgh CHD in Type 1 Diabetes Risk Mode

    Zgibor, J.C.; Ruppert, K.; Orchard, T.J.; Soedamah-Muthu, S.S.; Fuller, J.H.; Chaturvedi, N.; Roberts, M.S.

    2010-01-01

    Aim - To create a coronary heart disease (CHD) risk prediction model specific to type 1 diabetes. Methods - Development of the model used data from the Pittsburgh Epidemiology of Diabetes Complications Study (EDC). EDC subjects had type 1 diabetes diagnosed between 1950 and 1980, received their

  18. Pollutant Concentrations in Street Canyons of Different Aspect Ratio with Avenues of Trees for Various Wind Directions

    Gromke, Christof; Ruck, Bodo

    2012-07-01

    This study summarizes the effects of avenues of trees in urban street canyons on traffic pollutant dispersion. We describe various wind-tunnel experiments with different tree-avenue models in combination with variations in street-canyon aspect ratio W/ H (with W the street-canyon width and H the building height) and approaching wind direction. Compared to tree-free street canyons, in general, higher pollutant concentrations are found. Avenues of trees do not suppress canyon vortices, although the air ventilation in canyons is hindered significantly. For a perpendicular wind direction, increases in wall-average and wall-maximum concentrations at the leeward canyon wall and decreases in wall-average concentrations at the windward wall are found. For oblique and perpendicular wind directions, increases at both canyon walls are obtained. The strongest effects of avenues of trees on traffic pollutant dispersion are observed for oblique wind directions for which also the largest concentrations at the canyon walls are found. Thus, the prevailing assumption that attributes the most harmful dispersion conditions to a perpendicular wind direction does not hold for street canyons with avenues of trees. Furthermore, following dimensional analysis, an estimate of the normalized wall-maximum traffic pollutant concentration in street canyons with avenues of trees is derived.

  19. Results of the radiological survey at 1047 Central Avenue, Albany, New York (AL209)

    Hall, S.C.; Marley, J.L.

    1987-11-01

    A number of properties in the Albany/Colonie area have been identified as being potentially contaminated with uranium originating from the former National Lead Company's uranium forming plant in Colonie, New York. The property at 1047 Central Avenue in Albany, New York was the subject of a radiological investigation initiated August 26, 1986. The commercial property consists of a two-story frame building located on an irregular lot. An asphalt drive connects the property to the street. A diagram of the property showing the approximate boundaries and the 6-m grid network established for measurements outside the building is shown. The lot included in the radiological survey was /approximately/18 m wide by 60 m deep. Front and rear views of the property are shown. 13 refs., 5 figs., 5 tabs

  20. Results of the radiological survey at 7 Maplewood Avenue, Colonie, New York

    Marley, J.L.

    1987-12-01

    A number of properties in the Albany/Colonie area have been identified as being potentially contaminated with uranium originating from the former National Lead Company's uranium forming plant in Colonie, New York. The property at 7 Maplewood Avenue in Colonie, New York, was the subject of a radiological investigation initiated May 8, 1986. The residential property consisted of a house and a garage located on a rectangular lot. An asphalt-paved driveway connected the garage with the street. A diagram of the property showing the approximate boundaries and the 4-m grid network established for measurements outside the house is shown. The lot included in the radiological survey was /approximately/12 m wide by 35.5 m deep. Front and rear views of the property are shown. 13 refs., 5 figs., 5 tabs

  1. Results of the radiological survey at 23 Yardboro Avenue, Albany, New York (AL138)

    Marley, J.L.

    1987-12-01

    A number of properties in the Albany/Colonie area have been identified as being potentially contaminated with uranium originating from the former National Lead Company's uranium forming plant in Colonie, New York. The property at 23 Yardboro Avenue in Albany, New York (AL138) was the subject of a radiological investigation initiated May 7, 1986. The property was a residence with a one and one-half-story frame house located on a rectangular lot. An asphalt driveway or parking area is located at the east side of the house. An area of /approximately/10 m /times/ 14 m at the rear was inaccessible. A diagram of the property showing the approximate boundaries and the 3-m grid network established for measurements outside the house is shown. The lot included in the radiological survey was /approximately/14 m wide by 36 m deep. Front and rear views of the property are shown. 13 refs., 5 figs., 5 tabs

  2. Results of the radiological survey at 1054 Central Avenue, Albany, New York (AL211)

    Hall, S.C.; Marley, J.L.

    1987-11-01

    A number of properties in the Albany/Colonie area have been identified as being potentially contaminated with uranium originating from the former National Lead Company's uranium forming plant in Colonie, New York. The property at 1054 Central Avenue in Albany, New York was the subject of a radiological investigation initiated August 27, 1986. The commercial property consists of a two-story frame and block building located on a rectangular lot. An asphalt drive connects the working areas to the street. A diagram of the property showing the approximate boundaries and the 5-m grid network established for measurements outside the building is shown. The lot included in the radiological survey was /approximately/13 m wide by 43 m deep. Front and side views of the property are shown. 13 refs., 5 figs., 5 tabs

  3. Results of the radiological survey at 136 West Central Avenue (MJ030), Maywood, New Jersey

    Foley, R.D.; Crutcher, J.W.; Carrier, R.F.; Floyd, L.M.

    1989-02-01

    As a result of the Energy and Water Appropriations Act of Fiscal Year 1984, the property discussed in this report and properties in its vicinity contaminated with residues from the former Maywood Chemical Works (MCW) were included as a decontamination research and development project under the DOE Formerly Utilized Sites Remedial Action Program. As part of this project, DOE is conducting radiological surveys in the vicinity of the site to identify properties contaminated with residues derived from the MCW. The principal radionuclide of concern is thorium-232. The radiological survey discussed in this report is part of that effort and was conducted, at the request of DOE by members of the Measurement Applications and Development Group of Oak Ridge National Laboratory. A radiological survey of the private, residential property at 136 West Central Avenue, Maywood, New Jersey, was conducted during 1987. The survey and sampling of the ground surface and subsurface were carried out on April 29, 1987

  4. Results of the radiological survey at West Hunter Avenue Firehall, Maywood, New Jersey (MJ027)

    Foley, R.D.; Floyd, L.M.

    1990-03-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, West Hunter Avenue Firehall, Maywood, New Jersey (MJ027), was conducted during 1987. 4 refs., 3 tabs

  5. Capturing the Material Invisible: OGS Crawford, Ghosts, and the Stonehenge Avenue

    Martyn Barber

    2016-11-01

    Full Text Available Why do archaeologists excavate? What should we expect from archaeological archives? OGS Crawford’s discovery and excavation of the course of the Stonehenge Avenue in the summer of 1923 – perhaps the first time that a cropmark was identified on an aerial photograph and the first such site to be excavated, and moreover a discovery that had considerable impact on the understanding of Stonehenge’s construction and its relationship with the wider landscape – has left virtually no material trace within the relevant archives. This paper aims to offer an explanation for that absence, and to shed some light on Crawford’s belief that his excavations were unlikely to yield ‘tangible results’.

  6. Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues

    Kutty Selva Nandakumar

    2018-02-01

    Full Text Available Rheumatoid arthritis (RA is a polygenic and multifactorial syndrome. Many complex immunological and genetic interactions are involved in the final outcome of the clinical disease. Autoantibodies (rheumatoid factors, anti-citrullinated peptide/protein antibodies are present in RA patients’ sera for a long time before the onset of clinical disease. Prior to arthritis onset, in the autoantibody response, epitope spreading, avidity maturation, and changes towards a pro-inflammatory Fc glycosylation phenotype occurs. Genetic association of epitope specific autoantibody responses and the induction of inflammation dependent and independent changes in the cartilage by pathogenic autoantibodies emphasize the crucial contribution of antibody-initiated inflammation in RA development. Targeting IgG by glyco-engineering, bacterial enzymes to specifically cleave IgG/alter N-linked Fc-glycans at Asn 297 or blocking the downstream effector pathways offers new avenues to develop novel therapeutics for arthritis treatment.

  7. Finding ways to say 'yes': report of the Laurier Avenue geothermal project

    NONE

    2010-09-30

    RESCo Energy Inc. (RESCo), Booz Engineering and R. Mancini And Associates were requested by Laurier Avenue residents and the Don Vale Cabbagetown Residents Association Inc. to work together to provide an engineering study on the feasibility of using geo-exchange heating and cooling for the heritage homes in the Laurier Avenue neighbourhood. The main purpose of the analysis was to examine the potential application of geothermal heating and other energy efficiency technologies in a heritage neighbourhood in Toronto. The study was also designed to evaluate the options to preserve ground-water run-off using permeable pavement solutions during road reconstruction. Aside from the comparison between existing technologies, this project also integrates political, bureaucratic, legal and financing aspects. Baseline conditions of the homes were identified and eco-energy audits were performed on some of them. Energy efficiencies are generally low in these homes and heating systems are not appropriate. Nevertheless, utility costs are generally moderate thanks to the small size and the proximity of the houses. Although they are effective, geo-exchange systems are expensive and still difficult to implement in an urban environment. The challenges they have to face involve using city property for borefields, heritage concerns, archaeological preservation and financial aspects. The scope of the study includes other efficiency technologies such as air source heat pumps, home air sealing and insulation upgrades and high efficiency hot water systems. The potential for electricity generation using renewable energy is limited by the site conditions. Considering Toronto's ambitions regarding energy-efficiency and GHG reductions, it will be necessary to identify solutions to reduce bureaucratic barriers to citizen initiatives like the one described here.

  8. GIS-Based Planning and Modeling for Renewable Energy: Challenges and Future Research Avenues

    Bernd Resch

    2014-05-01

    Full Text Available In the face of the broad political call for an “energy turnaround”, we are currently witnessing three essential trends with regard to energy infrastructure planning, energy generation and storage: from planned production towards fluctuating production on the basis of renewable energy sources, from centralized generation towards decentralized generation and from expensive energy carriers towards cost-free energy carriers. These changes necessitate considerable modifications of the energy infrastructure. Even though most of these modifications are inherently motivated by geospatial questions and challenges, the integration of energy system models and Geographic Information Systems (GIS is still in its infancy. This paper analyzes the shortcomings of previous approaches in using GIS in renewable energy-related projects, extracts distinct challenges from these previous efforts and, finally, defines a set of core future research avenues for GIS-based energy infrastructure planning with a focus on the use of renewable energy. These future research avenues comprise the availability base data and their “geospatial awareness”, the development of a generic and unified data model, the usage of volunteered geographic information (VGI and crowdsourced data in analysis processes, the integration of 3D building models and 3D data analysis, the incorporation of network topologies into GIS, the harmonization of the heterogeneous views on aggregation issues in the fields of energy and GIS, fine-grained energy demand estimation from freely-available data sources, decentralized storage facility planning, the investigation of GIS-based public participation mechanisms, the transition from purely structural to operational planning, data privacy aspects and, finally, the development of a new dynamic power market design.

  9. Results of the radiological survey at 146 W. Central Avenue, Maywood, New Jersey (MJ034)

    Foley, R.D.; Carrier, R.F.

    1989-11-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and reining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from OaK Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. These surveys typically include direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, a private property at 146 West Central Avenue, Maywood, New Jersey (MJ034), was conducted during 1987 and 1988. While some measurements at this property were greater than background levels typically encountered in the New jersey area, no radiation levels nor radionuclide concentrations exceeded the guidelines established by the DOE for the Maywood, New Jersey, area remedial action plan. However, because of the proximity of the railroad property, which will be remediated, and the DOE's ALARA (As Low As Reasonably Achievable) policy, concurrent removal of the slightly elevated soil layers at 146 W. Central Avenue may be justified. 6 refs., 6 figs., 3 tabs

  10. Finding ways to say 'yes': report of the Laurier Avenue geothermal project

    2010-01-01

    RESCo Energy Inc. (RESCo), Booz Engineering and R. Mancini And Associates were requested by Laurier Avenue residents and the Don Vale Cabbagetown Residents Association Inc. to work together to provide an engineering study on the feasibility of using geo-exchange heating and cooling for the heritage homes in the Laurier Avenue neighbourhood. The main purpose of the analysis was to examine the potential application of geothermal heating and other energy efficiency technologies in a heritage neighbourhood in Toronto. The study was also designed to evaluate the options to preserve ground-water run-off using permeable pavement solutions during road reconstruction. Aside from the comparison between existing technologies, this project also integrates political, bureaucratic, legal and financing aspects. Baseline conditions of the homes were identified and eco-energy audits were performed on some of them. Energy efficiencies are generally low in these homes and heating systems are not appropriate. Nevertheless, utility costs are generally moderate thanks to the small size and the proximity of the houses. Although they are effective, geo-exchange systems are expensive and still difficult to implement in an urban environment. The challenges they have to face involve using city property for borefields, heritage concerns, archaeological preservation and financial aspects. The scope of the study includes other efficiency technologies such as air source heat pumps, home air sealing and insulation upgrades and high efficiency hot water systems. The potential for electricity generation using renewable energy is limited by the site conditions. Considering Toronto's ambitions regarding energy-efficiency and GHG reductions, it will be necessary to identify solutions to reduce bureaucratic barriers to citizen initiatives like the one described here.

  11. Autonomy, Affinity, and the Assessment of Damages: Acb v Thomson Medical Pte Ltd [2017] SGCA 20 and Shaw v Kovak [2017] EWCA Civ 1028.

    Purshouse, Craig

    2017-11-17

    In ACB v Thomson Medical Pte Ltd [2017] SGCA 20 and Shaw v Kovak [2017] EWCA Civ 1028, the idea that 'lost autonomy' should be recognised as a new form of actionable damage in the tort of negligence was rejected in Singapore and England, respectively. This, it will be argued, was the correct outcome. Protecting an interest in autonomy via the tort of negligence would undermine the coherence of that tort. In ACB, however, a new, different, form of damage was recognised: loss of 'genetic affinity'. This commentary will discuss some problems that protecting an interest in 'genetic affinity' raises before critiquing the approach to assessing damages in ACB. © The Author 2017. Published by Oxford University Press; all rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. Psychometric properties of the Brazilian version of the Pittsburgh Sleep Quality Index Addendum for PTSD (PSQI-A

    Jair B. Barbosa Neto

    2014-12-01

    Full Text Available Objective: Sleep disturbances play a fundamental role in the pathophysiology posttraumatic stress disorder (PTSD, and are not only a secondary feature. The aim of this study was to validate and assess the psychometric properties of the Brazilian version of the Pittsburgh Sleep Quality Index Addendum for PTSD (PSQI-A-BR, a self-report instrument designed to assess the frequency of seven disruptive nocturnal behaviors, in a sample of participants with and without PTSD. Methods: PSQI-A was translated into Brazilian Portuguese and applied to a convenience sample of 190 volunteers, with and without PTSD, who had sought treatment for the consequences of a traumatic event. Results: The PSQI-A-BR displayed satisfactory internal consistency (Cronbach's coefficient of 0.83 between all items and convergent validity with the Clinician Administered PTSD Scale (CAPS, even when excluding sleep-related items (r = 0.52. Test-retest yielded high agreement in the global PSQI-A-BR, with good stability over time (r = 0.88. A global PSQI-A-BR cutoff score of 7 yielded a sensitivity of 79%, specificity of 64%, and a global score of 7 yielded a positive predictive value of 93% for discriminating participants with PTSD from those without PTSD. Conclusion: The PSQI-A-BR is a valid instrument for PTSD assessment, applicable to both clinical and research settings.

  13. Melatonin effects on Plasmodium life cycle: new avenues for therapeutic approach.

    Srinivasan, Venkataramanujam; Ahmad, Asma H; Mohamed, Mahaneem; Zakaria, Rahimah

    2012-05-01

    Malaria remains a global health problem affecting more than 515 million people all over the world including Malaysia. It is on the rise, even within unknown regions that previous to this were free of malaria. Although malaria eradication programs carried out by vector control programs are still effective, anti-malarial drugs are also used extensively for curtailing this disease. But resistance to the use of anti-malarial drugs is also increasing on a daily basis. With an increased understanding of mechanisms that cause growth, differentiation and development of malarial parasites in rodents and humans, new avenues of therapeutic approaches for controlling the growth, synchronization and development of malarial parasites are essential. Within this context, the recent discoveries related to IP3 interconnected signalling pathways, the release of Ca2+ from intracellular stores of Plasmodium, ubiquitin protease systems as a signalling pathway, and melatonin influencing the growth and differentiation of malarial parasites by its effects on these signalling pathways have opened new therapeutic avenues for arresting the growth and differentiation of malarial parasites. Indeed, the use of melatonin antagonist, luzindole, has inhibited the melatonin's effect on these signalling pathways and thereby has effectively reduced the growth and differentiation of malarial parasites. As Plasmodium has effective sensors which detect the nocturnal plasma melatonin concentrations, suppression of plasma melatonin levels with the use of bright light during the night or by anti-melatonergic drugs and by using anti-kinase drugs will help in eradicating malaria on a global level. A number of patients have been admitted with regards to the control and management of malarial growth. Patents related to the discovery of serpentine receptors on Plasmodium, essential for modulating intra parasitic melatonin levels, procedures for effective delivery of bright light to suppress plasma melatonin

  14. Billboard advertising: an avenue for communicating healthcare information and opportunities to disadvantaged populations.

    Elrod, James K; Fortenberry, John L

    2017-12-13

    Healthcare communications directed toward the disadvantaged have the potential to elevate the health status of these underprivileged and highly-challenged individuals. From conveying advice which encourages healthy lifestyles to communicating the location and availability of various medical resources, healthier lives and communities can be realized. Success on this front first requires establishing an effective communications link, something that is made more difficult as communications options available to the disadvantaged are more limited than those available to advantaged populations. One avenue which shows exceptional promise for successfully engaging the disadvantaged is that of billboard advertising. Willis-Knighton Health System's experiences and insights indicate that the characteristics and qualities of billboards, paired with the environmental circumstances typically faced by the less fortunate, create unique combinations which amplify consumption of billboard advertising content. Further, research suggests that the less privileged place greater reliance on the medium than do their more privileged counterparts, escalating the value and impact potential of billboard advertising directed toward the disadvantaged. Given the value afforded by health and wellness information successfully reaching the disadvantaged, opportunities to better distribute content to targeted audiences could very well improve community health. Billboard advertising appears to be well suited to engage the less fortunate, providing a productive pathway for the conveyance of helpful, supportive details, yielding healthier populations, enhanced opportunities, and better communities.

  15. Purification and Phytotoxic Analysis of Botrytis cinerea Virulence Factors: New Avenues for Crop Protection

    Maria R. Davis

    2012-07-01

    Full Text Available Botrytis cinerea is a necrotrophic fungus infecting over 230 plant species worldwide. This highly adaptable pathogen can afflict agricultural products from seed to storage, causing significant economic losses and instability in the food supply. Small protein virulence factors secreted by B. cinerea during infection play an important role in initiation and spread of disease. BcSnod1 was found to be abundantly expressed upon exposure to media containing strawberry extract. From sequence similarity, BcSnod2 was also identified and both were recognized as members of the Ceratoplatanin family of small phytotoxic proteins. Recombinant BcSnod1 was shown to have a phytotoxic effect and play an important role in pathogenicity while the role of BcSnod2 remains less clear. Both bacterial and yeast production systems are reported, though the bacterial protein is less toxic and mostly unfolded relative to that made in yeast. Compared to BcSnod1, recombinant bacterial BcSnod2 shows similar, but delayed phytotoxicity on tomato leaves. Further studies of these critical virulence factors and their inhibition promise to provide new avenues for crop protection.

  16. Paradoxical thinking as a new avenue of intervention to promote peace.

    Hameiri, Boaz; Porat, Roni; Bar-Tal, Daniel; Bieler, Atara; Halperin, Eran

    2014-07-29

    In societies involved in an intractable conflict, there are strong socio-psychological barriers that contribute to the continuation and intractability of the conflict. Based on a unique field study conducted in the context of the Israeli-Palestinian conflict, we offer a new avenue to overcome these barriers by exposing participants to a long-term paradoxical intervention campaign expressing extreme ideas that are congruent with the shared ethos of conflict. Results show that the intervention, although counterintuitive, led participants to express more conciliatory attitudes regarding the conflict, particularly among participants with center and right political orientation. Most importantly, the intervention even influenced participants' actual voting patterns in the 2013 Israeli general elections: Participants who were exposed to the paradoxical intervention, which took place in proximity to the general elections, reported that they tended to vote more for dovish parties, which advocate a peaceful resolution to the conflict. These effects were long lasting, as the participants in the intervention condition expressed more conciliatory attitudes when they were reassessed 1 y after the intervention. Based on these results, we propose a new layer to the general theory of persuasion based on the concept of paradoxical thinking.

  17. Results of the radiological survey at 110 E Hunter Avenue, Maywood, New Jersey (MJ022)

    Foley, R.D.; Carrier, R.F.; Floyd, L.M.; Crutcher, J.W.

    1989-09-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 110 E. Hunter Avenue, Maywood, New Jersey (MJ022), was conducted during 1987. Following the removal of a small chunk of material showing elevated gamma exposure rates, all radionuclide concentrations and measurements conformed to DOE remedial action criteria. The slightly elevated radionuclide concentrations found in other soil samples were the result of naturally enhances radioactivity characteristic of some environmental materials such as coal ash and were unrelated to operations at the MCW site. The survey data demonstrate that the property requires no further action on the part of DOE. 4 refs., 2 figs., 3 tabs

  18. Micropropagation of Crataeva adansonii D.C. Prodr: an ornamental avenue tree.

    Tyagi, Purnima; Sharma, P K; Kothari, S L

    2010-01-01

    In this chapter, we describe multiplication of the superior and elite tree of Crataeva adansonii using plant tissue culture techniques. An ornamental and avenue tree, it is not available in abundance because of poor seed germination and seedling establishment. It reproduces in nature by root suckers, but that restricts its distribution to very limited areas. Efficient procedures are outlined for plant regeneration through direct shoot bud formation, indirect organogenesis, and somatic embryogenesis through callus formation. Different explants were utilized for separate pathways of regeneration. Murashige and Skoog's (MS) medium containing 3 mg/L BA and 0.05-0.1 mg/L NAA is most effective in direct induction of axillary buds from nodal explants and shoot tips. Adventitious shoots developed from leaves on MS medium containing 3 mg/L BA and 0.1 mg/L NAA. De novo shoots were obtained from the anthers on MS medium supplemented with 3 mg/L BA. Somatic embryos developed on half strength MS medium containing 0.1 mg/L 2, 4-D. Roots were induced at the cut ends of shoots on MS basal medium devoid of growth regulators. The plantlets were then transferred to pots.

  19. Results of the radiological survey at 88 East Central Avenue, Maywood, New Jersey (MJ037)

    Foley, R.D.; Crutcher, J.W.

    1989-06-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 88 East Central Avenue Maywood, New Jersey (MJ037), was conducted during 1988. Results of the survey indicated radioactivity in the range of normal background for the northern New Jersey area. Radiological assessments of soil samples from the site demonstrate no radionuclide concentrations in excess of DOE Formerly Utilized Sites Remedial Action Program criteria. 4 refs., 2 figs., 3 tabs

  20. Results of the radiological survey at 99 Garibaldi Avenue, Lodi, New Jersey (LJ064)

    Foley, R.D.; Floyd, L.M.; Crutcher, J.W.

    1989-07-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 99 Garibaldi Avenue, Lodi, New Jersey (LJ064), was conducted during 1987. Results of the survey demonstrated radionuclide concentrations in excess of the DOE Formerly Utilized Sites Remedial Action Program criteria. The radionuclide distributions are typical of the type of material originating from the MCW site. 4 refs., 8 figs., 3 tabs

  1. Results of the radiological survey at 112 Avenue E, Lodi, New Jersey (LJ082)

    Foley, R.D.; Floyd, L.M.

    1989-06-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residue, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 112 Avenue E, Lodi, New Jersey (LJ082), was conducted during 1988. Results of the survey demonstrated radionuclide concentrations in excess of the DOE Formerly Utilized Sites Remedial Action Program criteria. The radionuclide distributions are typical of the type of material originating from the MCW site. 2 figs., 3 tabs

  2. Results of the radiological survey at 108 Avenue E, Lodi, New Jersey (LJ084)

    Foley, R.D.; Floyd, L.M.

    1989-06-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 108 Avenue E, Lodi, New Jersey (LJ084), was conducted during 1988. Results of the survey demonstrated radionuclide concentrations in excess of the DOE Formerly Utilized Sites Remedial Action Program criteria. The radionuclide distributions are typical of the type of material originating from the MCW site. 5 refs., 2 figs., 2 tabs

  3. Results of the radiological survey at 137 Maywood Avenue, Maywood, New Jersey (MJ026)

    Foley, R.D.; Carrier, R.F.

    1989-12-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 137 Maywood Avenue, Maywood, New Jersey (MJ026), was conducted during 1987. 6 refs., 2 figs., 3 tabs

  4. Results of the radiological survey at 79 Avenue B, Lodi, New Jersey (LJ091)

    Foley, R.D.; Floyd, L.M.

    1989-06-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 79 Avenue B, Lodi, New Jersey (LJ091), was conducted during 1988. Results of the survey demonstrated radionuclide concentrations in excess of the DOE Formerly Utilized Sites Remedial Action Program criteria. The radionuclide distributions are typical of the type of material originating from the MCW site. 5 refs., 2 figs., 2 tabs

  5. Results of the radiological survey at 130 West Central Avenue, Maywood, New Jersey (MJ029)

    Foley, R.D.; Floyd, L.M.; Carrier, R.F.

    1989-10-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclides analyses. The survey of this site, 130 West Central Avenue, Maywood, New Jersey (MJ029), was conducted during 1987 and 1988. Some radionuclide measurements were greater than typical background levels in the northern New Jersey area. However, results of the survey demonstrated no radionuclide concentrations in excess of the DOE Formerly Utilized Sites Remedial Action program criteria. 4 refs., 7 figs., 3 tabs

  6. Results of the radiological survey at 21 West Central Avenue, Maywood, New Jersey (MJ046)

    Foley, R.D.; Floyd, L.M.

    1989-11-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 21 West Central Avenue, Maywood, New Jersey (MJ046), was conducted during 1988. 5 refs., 2 figs., 3 tabs

  7. Results of the radiological survey at 133 Maywood Avenue, Maywood, New Jersey (MJ025)

    Foley, R.D.; Carrier, R.F.; Floyd, L.M.; Crutcher, J.W.

    1989-10-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 133 Maywood Avenue, Maywood, New Jersey (MJ025), was conducted during 1987. The survey results demonstrate that all radionuclide concentrations and measurements conform to DOE remedial action criteria. All values are at or below typical background values found in northern New Jersey. 5 refs., 2 figs., 3 tabs

  8. Results of the radiological survey at 113 Avenue E, Lodi, New Jersey (LJ081)

    Foley, R.D.; Floyd, L.M.

    1989-06-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 113 Avenue E, Lodi, New Jersey (LJ081), was conducted during 1988. Results of the survey demonstrated radionuclide concentrations in excess of the DOE Formerly Utilized Sites Remedial Action Program criteria. The radionuclide distributions are typical of the type of material originating from the MCW site. 5 refs, 2 figs., 3 tabs

  9. Results of the radiological survey at 266 East Spring Valley Avenue (MJ024), Hackensack, New Jersey

    Foley, R.D.; Crutcher, J.W.; Carrier, R.F.; Floyd, L.M.

    1989-02-01

    As a result of the Energy and Water Appropriations Act of Fiscal Year 1984, the property discussed in this report and properties in its vicinity contaminated with residues from the former Maywood Chemical Works (MCW) were included as a decontamination research and development project under the DOE Formerly Utilized Sites Remedial Action Program. As part of this project, DOE is conducting radiological surveys in the vicinity of the site to identify properties contaminated with residues derived from the MCW. The principal radionuclide of concern is thorium-232. The radiological survey discussed in this report is part of that effort and was conducted, at the request of DOE, by members of the Measurement Applications and Development Group of Oak Ridge National Laboratory. A radiological survey of the private, residential property at 266 East Spring Valley Avenue, Hackensack, New Jersey, was conducted during 1987. The survey and sampling of the ground surface and subsurface were carried out on April 23, 1987. 4 refs., 2 figs., 3 tabs

  10. Repopulating Decellularized Kidney Scaffolds: An Avenue for Ex Vivo Organ Generation

    Robert A. McKee

    2016-03-01

    Full Text Available Recent research has shown that fully developed organs can be decellularized, resulting in a complex scaffold and extracellular matrix (ECM network capable of being populated with other cells. This work has resulted in a growing field in bioengineering focused on the isolation, characterization, and modification of organ derived acellular scaffolds and their potential to sustain and interact with new cell populations, a process termed reseeding. In this review, we cover contemporary advancements in the bioengineering of kidney scaffolds including novel work showing that reseeded donor scaffolds can be transplanted and can function in recipients using animal models. Several major areas of the field are taken into consideration, including the decellularization process, characterization of acellular and reseeded scaffolds, culture conditions, and cell sources. Finally, we discuss future avenues based on the advent of 3D bioprinting and recent developments in kidney organoid cultures as well as animal models of renal genesis. The ongoing mergers and collaborations between these fields hold the potential to produce functional kidneys that can be generated ex vivo and utilized for kidney transplantations in patients suffering with renal disease.

  11. Invited commentary: Personality phenotype and mortality--new avenues in genetic, social, and clinical epidemiology.

    Chapman, Benjamin P

    2013-09-01

    In this issue of the Journal, Jokela et al. (Am J Epidemiol. 2013;178(5):667-675) scrutinize the association between personality phenotype and all-cause mortality in remarkable detail by using an "individual-participant meta-analysis" design. Across 7 large cohorts varying in demographics and methods of personality measurement, they find varying prospective associations for 4 dimensions of the five-factor (or "Big Five") model of personality, but robust and consistent prospective associations for Big Five dimension of "conscientiousness." Jokela et al. place an important exclamation point on a long era of study of this topic and hint directly and indirectly at new avenues for this line of research. I consider the following 3 areas particularly rife for further inquiry: the role of genetics in personality and health studies; the role of personality in social inequalities in health; and the health policy and clinical implications of work like that of Jokela et al., including the potential role of personality phenotype in the evolution of personalized medicine.

  12. Results of the radiological survey at 90 C Avenue, Lodi, New Jersey (LJ079)

    Foley, R.D.; Floyd, L.M.

    1989-06-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducted an investigative radiological survey during 1988 at 90 C Avenue, Lodi, New Jersey (LJ079), one of the properties in the vicinity of the MCW site. The survey included a gamma radiation scan of the surface and at one meter above the surface, as well as radionuclide sampling of surface and subsurface soil. The survey objective was to determine whether this site was contaminated with radioactive residues derived from MCW, principally 232 Th. Results of the survey demonstrated radionuclide concentrations in excess of DOE remedial action criteria, primarily from the 232 Th decay chain, with some contamination from 226 Ra. The radionuclide distributions are typical of the type of material originating from the MCW site. 5 refs., 3 figs., 3 tabs

  13. Lost in translation. New unexplored avenues for neuropsychopharmacology: epigenetics and microRNAs.

    Tardito, Daniela; Mallei, Alessandra; Popoli, Maurizio

    2013-02-01

    Mood and anxiety disorders are among the major causes of disability worldwide. Despite clear need for better therapies, efforts to develop novel drugs have been relatively unsuccessful. One major reason is lack of translation into neuropsychopharmacology of the impressive recent array of knowledge accrued by clinical and preclinical researches on the brain. Here focus is on epigenetics mechanisms, including microRNAs, which seem particularly promising for the identification of new targets for alternative pharmacological approaches. First, the current knowledge about epigenetic mechanisms, including DNA methylation, posttranslational modification of histone proteins, focusing on histone methylation and acetylation, and posttranscriptional modulation of gene expression by microRNAs is described. Then evidence showing involvement of epigenetics and microRNAs in the pathophysiology of mood and anxiety disorders as well as evidence showing that some of the currently employed antidepressants and mood stabilizers also affect epigenetic and microRNA mechanisms are reviewed. Finally current evidence and novel approaches in favor of drugs regulating epigenetic and microRNA mechanisms as potential therapeutics for these disorders are discussed. Although still in its infancy, research investigating the effects of pharmacological modulation of epigenetic and microRNA mechanisms in neuropsychiatric disorders continues to provide encouraging findings, suggesting new avenues for treatment of mood and anxiety disorders.

  14. A systematic review of satisfaction and pediatric obesity treatment: new avenues for addressing attrition.

    Skelton, Joseph A; Irby, Megan Bennett; Geiger, Ann M

    2014-01-01

    Pediatric obesity treatment programs report high attrition rates, but it is unknown if family experience and satisfaction contributes. This review surveys the literature regarding satisfaction in pediatric obesity and questions used in measurement. A systematic review of the literature was conducted using Medline, PsychINFO, and CINAHL. Studies of satisfaction in pediatric weight management were reviewed, and related studies of obesity were included. Satisfaction survey questions were obtained from the articles or from the authors. Eighteen studies were included; 14 quantitative and 4 qualitative. Only one study linked satisfaction to attrition, and none investigated the association of satisfaction and weight outcomes. Most investigations included satisfaction as a secondary aim or used single-item questions of overall satisfaction; only one assessed satisfaction in noncompleters. Overall, participants expressed high levels of satisfaction with obesity treatment or prevention programs. Surveys focused predominantly on overall satisfaction or specific components of the program. Few in-depth studies of satisfaction with pediatric obesity treatment have been conducted. Increased focus on family satisfaction with obesity treatment may provide an avenue to lower attrition rates and improve outcomes. Enhancing measurement of satisfaction to yield actionable responses could positively influence outcomes, and a framework, via patient-centered care principles, is provided. © 2013 National Association for Healthcare Quality.

  15. Results of the radiological survey at 142 West Central Avenue, Maywood, New Jersey (MJ041)

    Foley, R.D.; Crutcher, J.W.

    1989-06-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 142 West Central Avenue, Maywood, New Jersey (MJ041), was conducted during 1988. Results of the survey indicated scattered radiation or ''shine'' from a storage pile, located off the property, containing residual radioactive material. Lead-shielded measurements showed radioactivity in the range of normal background for the northern New Jersey area. Radiological assessments of soil samples from the site demonstrate no radionuclide concentrations in excess of DOE Formerly Utilized Sites Remedial Action Program criteria. 4 refs., 8 figs., 3 tabs

  16. Results of the radiological survey at 83 Belle Avenue, Maywood, New Jersey (MJ047)

    Foley, R.D.; Floyd, L.M.

    1989-11-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 83 Belle Avenue, Maywood, New Jersey (MJ047), was conducted during 1988. 5 refs., 2 figs., 3 tabs

  17. Results of the radiological survey at 105 Garibaldi Avenue, Lodi, New Jersey (LJ065)

    Foley, R.D.; Floyd, L.M.; Carrier, R.F.

    1989-11-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 105 Garibaldi Avenue, Lodi, New Jersey (LJ065), was conducted during 1987. 4 refs., 4 figs., 3 tabs

  18. Results of the radiological survey at 104 Avenue E, Lodi, New Jersey (LJ086)

    Foley, R.D.; Floyd, L.M.

    1989-12-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, 104 Avenue E, Lodi, New Jersey (LJ086), was conducted during 1988. 5 refs., 2 figs., 3 tabs

  19. Staff Development as an Imperative Avenue in Ensuring Quality: The Experience of Adama University

    Yilfashewa Seyoum

    2012-01-01

    Full Text Available All endeavors were devoted to investigate the views and feelings of stakeholders on the implementation of teachers’ professional development and its contribution to sustain academic programs quality at Adama University. A case study that constitutes qualitative and quantitative method was employed. In an attempt to achieve the objectives of the study, evidences were collected from students, staff members, professional development program coordinators, and management bodies. The data-collecting instruments for obtaining relevant information were questionnaires, interview, observation, and document analysis. The finding in relation to this study uncovers the fact that though continuous professional development has been perceived as the most useful avenue of teachers continuous and lifelong learning, for the most part, it is relegated to adhoc committees or interested group or institutional units in the system of university education/training. Moreover, the absence of PDP in the university organizational structure, clear mission and vision, defined and well-articulated policy, strategic plan, representatives in university senate meetings, adequate resources, well-identified and -preserved training facilities, and unit library were circumstances that in one way or another negatively affected the provision of effective professional development programs/trainings that may have adverse effect in the deliberation of quality education/training in Adama University.

  20. Substance use by Egyptian youth: current patterns and potential avenues for prevention.

    Loffredo, Christopher A; Boulos, Dina N K; Saleh, Doa'a A; Jillson, Irene A; Garas, Magdy; Loza, Nasser; Samuel, Philip; Shaker, Yousri Edward; Ostrowski, Mar-Jan; Amr, Sania

    2015-04-01

    Substance abuse in Egypt is a serious public health threat. Recent studies have demonstrated increases in the prevalence of the use of tobacco, illegal drugs, and over-the-counter drugs, particularly among youth. We conducted focus groups with a total of 40 male and female youth participants, ages 12-14 and 15-18, recruited from two different areas (Cairo and Alexandria) in 2012. We investigated their knowledge and perceptions regarding current substance use, its sources, and promoting and protecting factors, broadly addressing the use of tobacco products, illicit and prescription drugs, inhaled substances such as glue and solvents, and alcohol. Our findings suggest that: (1) youth in Egypt had access to and were actively using substances encountered in similar research worldwide, including tobacco, alcohol, illicit drugs, glue sniffing, and pharmaceutical agents; (2) smoking cigarettes and using hashish were the most common practices, and Tramadol was the most commonly used pharmaceutical drug; (3) peer pressure from friends stood out as the most common reason to start and continue using substances, followed by adverse life events and having a parent or family member who used substances; (4) strict parenting, religiosity, and having non-user friends were among the factors perceived by youth to prevent substance use or help them quit using substances; (5) most youths were aware of the adverse health effects of substance use. These findings will inform the design of quantitative surveys aimed at estimating the prevalence of specific behaviors related to substance use among youth and potential avenues for prevention.

  1. Update on novel targets and potential treatment avenues in pulmonary hypertension

    Huetsch, John C.; Suresh, Karthik; Bernier, Meghan

    2016-01-01

    Pulmonary hypertension (PH) is a condition marked by a combination of constriction and remodeling within the pulmonary vasculature. It remains a disease without a cure, as current treatments were developed with a focus on vasodilatory properties but do not reverse the remodeling component. Numerous recent advances have been made in the understanding of cellular processes that drive pathologic remodeling in each layer of the vessel wall as well as the accompanying maladaptive changes in the right ventricle. In particular, the past few years have yielded much improved insight into the pathways that contribute to altered metabolism, mitochondrial function, and reactive oxygen species signaling and how these pathways promote the proproliferative, promigratory, and antiapoptotic phenotype of the vasculature during PH. Additionally, there have been significant advances in numerous other pathways linked to PH pathogenesis, such as sex hormones and perivascular inflammation. Novel insights into cellular pathology have suggested new avenues for the development of both biomarkers and therapies that will hopefully bring us closer to the elusive goal: a therapy leading to reversal of disease. PMID:27591245

  2. [In vitro early detection of amyloid plaques in Alzheimer's disease by Pittsburgh compound B-modified magnetic nanoparticles].

    Zeng, J Q; Wu, J Q; Li, M H; Wang, P J

    2017-11-07

    Objective: To construct magnetic nanoparticles targeting β-amyloid (Aβ) plaques, the pathological biomarker of Alzheimer's disease (AD) and to study their binding capability in vitro . Methods: Superparamagnetic nanoparticles Mn(0.6)Zn(0.4)Fe(2)O(4) (MZF) were coated with amphiphilic star-block copolymeric micelles and modified with Aβ-specific probe Pittsburgh compound B (PiB) to construct a novel magnetic nanoparticle MZF-PiB, which specifically targeted amyloid plaques. Transmission electron microscope was used to study the morphological features of MZF-PiB. Superparamagnetism of MZF-PiB was assessed by its r(2) relaxation rate by using 3.0 T MRI scanner. Cytotoxic test was applied to determine biosafety of MZF-PiB nanoparticles in differentiated human neuroblastoma cells (SH-SY5Y) and Madin-Darby canine kidney (MDCK). In vitro binding tests were conducted via immunohistochemistry on 6-month old AD mice brain sections. Differences of cell viability between groups were compared with one-way analysis of variance. Results: MZF-PiB nanoparticles were successfully constructed. Transmission electron microscope images showed that the nanoparticles were about 100 nm in size. The r(2) relaxation rate was 163.11 mMS(-1). No differences were found in cell viability of SH-SY5Y and MDCK incubated with MZF-PiB suspension for 24 h or 48 h when compared with those of untreated cells ( F =2.336, 2.539, 0.293, 1.493, all P >0.05). In vitro binding tests indicated that the MZF-PiB were specifically bound to amyloid plaques. The smallest size of detected plaques was 27 μm. Conclusion: PiB-modified nanoparticles targeting Aβ are biologically safe and highly superparamagnetic, possessing the capability to detect amyloid plaques early in vitro and the potential for early diagnosis of AD.

  3. Amyloid imaging in cognitively normal older adults: comparison between 18F-flutemetamol and 11C-Pittsburgh compound B

    Adamczuk, Katarzyna; Schaeverbeke, Jolien; Neyens, Veerle; Dupont, Patrick; Nelissen, Natalie; Vandenbulcke, Mathieu; Goffin, Karolien; Lilja, Johan; Hilven, Kelly; Laere, Koen van; Vandenberghe, Rik

    2016-01-01

    Preclinical, or asymptomatic, Alzheimer's disease (AD) refers to the presence of positive AD biomarkers in the absence of cognitive deficits. This research concept is being applied to define target populations for clinical drug development. In a prospective community-recruited cohort of cognitively intact older adults, we compared two amyloid imaging markers within subjects: 18 F-flutemetamol and 11 C-Pittsburgh compound B (PIB). In 32 community-recruited cognitively intact older adults aged between 65 and 80 years, we determined the concordance between binary classification based on 18 F-flutemetamol versus 11 C-PIB according to semiquantitative assessment (standardized uptake value ratio in composite cortical volume, SUVR comp ) and, alternatively, according to visual reads. We also determined the correlation between 18 F-flutemetamol and 11 C-PIB SUVR and evaluated how this was affected by the reference region chosen (cerebellar grey matter versus pons) and the use of partial volume correction (PVC) in this population. Binary classification based on semiquantitative assessment was concordant between 18 F-flutemetamol and 11 C-PIB in 94 % of cases. Concordance of blinded binary visual reads between tracers was 84 %. The Spearman correlation between 18 F-flutemetamol and 11 C-PIB SUVR comp with cerebellar grey matter as reference region was 0.84, with a slope of 0.98. Correlations in neocortical regions were significantly lower with the pons as reference region. PVC improved the correlation in striatum and medial temporal cortex. For the definition of preclinical AD based on 18 F-flutemetamol, concordance with 11 C-PIB was highest using semiquantitative assessment with cerebellar grey matter as reference region. (orig.)

  4. Pittsburgh Compound B and AV-1451 positron emission tomography assessment of molecular pathologies of Alzheimer's disease in progressive supranuclear palsy.

    Whitwell, Jennifer L; Ahlskog, J Eric; Tosakulwong, Nirubol; Senjem, Matthew L; Spychalla, Anthony J; Petersen, Ronald C; Jack, Clifford R; Lowe, Val J; Josephs, Keith A

    2018-03-01

    Little is known about Alzheimer's disease molecular proteins, beta-amyloid and paired helical filament (PHF) tau, in progressive supranuclear palsy (PSP). Recent techniques have been developed to allow for investigations of these proteins in PSP. We determined the frequency of beta-amyloid deposition in PSP, and whether beta-amyloid deposition in PSP is associated with PHF-tau deposition pattern, or clinical features. Thirty probable PSP participants underwent MRI, [ 18 F]AV-1451 PET and Pittsburgh compound B (PiB) PET. Apolipoprotein (APOE) genotyping was also performed. A global PiB standard-uptake value ratio (SUVR) was calculated. AV-1451 SUVRs were calculated for a set of Alzheimer's disease (AD)-related regions and a set of PSP-related regions. Voxel-level analyses were conducted to assess for differences in AV-1451 uptake patterns and MRI atrophy between PiB(+) and PiB(-) cases compared to 60 normal PiB(-) controls. Statistical testing for correlations and associations between variables of interest were also performed. Twelve subjects (40%) showed beta-amyloid deposition. Higher PiB SUVR correlated with older age but not with AV-1451 SUVR in the AD- or PSP-related regions. Higher AV-1451 SUVR in AD-related regions was associated with higher AV-1451 SUVR in PSP-related regions. We found little evidence for beta-amyloid related differences in clinical metrics, proportion of APOE e4 carriers, pattern of AV-1451 uptake, or pattern of atrophy. Beta-amyloid deposition occurs in a relatively high proportion of PSP subjects. Unlike in Alzheimer's disease, however, there is little evidence that beta-amyloid, and PHF-tau, play a significant role in neurodegeneration in PSP. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. miRNAs in Tuberculosis: New Avenues for Diagnosis and Host-Directed Therapy

    Naveed Sabir

    2018-03-01

    Full Text Available Tuberculosis (TB is one of the most fatal infectious diseases and a leading cause of mortality, with 95% of these deaths occurring in developing countries. The causative agent, Mycobacterium tuberculosis (Mtb, has a well-established ability to circumvent the host’s immune system for its intracellular survival. microRNAs (miRNAs are small, non-coding RNAs having an important function at the post-transcriptional level and are involved in shaping immunity by regulating the repertoire of genes expressed in immune cells. It has been established in recent studies that the innate immune response against TB is significantly regulated by miRNAs. Moreover, differential expression of miRNA in Mtb infection can reflect the disease progression and may help distinguish between active and latent TB infection (LTBI. These findings encouraged the application of miRNAs as potential biomarkers. Similarly, active participation of miRNAs in modulation of autophagy and apoptosis responses against Mtb opens an exciting avenue for the exploitation of miRNAs as host directed therapy (HDT against TB. Nanoparticles mediated delivery of miRNAs to treat various diseases has been reported and this technology has a great potential to be used in TB. In reality, this exploitation of miRNAs as biomarkers and in HDT is still in its infancy stage, and more studies using animal models mimicking human TB are advocated to assess the role of miRNAs as biomarkers and therapeutic targets. In this review, we attempt to summarize the recent advancements in the role of miRNAs in TB as immune modulator, miRNAs’ capability to distinguish between active and latent TB and, finally, usage of miRNAs as therapeutic targets against TB.

  6. Allosteric modulation of endogenous metabolites as an avenue for drug discovery.

    Wootten, Denise; Savage, Emilia E; Valant, Celine; May, Lauren T; Sloop, Kyle W; Ficorilli, James; Showalter, Aaron D; Willard, Francis S; Christopoulos, Arthur; Sexton, Patrick M

    2012-08-01

    G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors and a key drug target class. Recently, allosteric drugs that can co-bind with and modulate the activity of the endogenous ligand(s) for the receptor have become a major focus of the pharmaceutical and biotechnology industry for the development of novel GPCR therapeutic agents. This class of drugs has distinct properties compared with drugs targeting the endogenous (orthosteric) ligand-binding site that include the ability to sculpt cellular signaling and to respond differently in the presence of discrete orthosteric ligands, a behavior termed "probe dependence." Here, using cell signaling assays combined with ex vivo and in vivo studies of insulin secretion, we demonstrate that allosteric ligands can cause marked potentiation of previously "inert" metabolic products of neurotransmitters and peptide hormones, a novel consequence of the phenomenon of probe dependence. Indeed, at the muscarinic M(2) receptor and glucagon-like peptide 1 (GLP-1) receptor, allosteric potentiation of the metabolites, choline and GLP-1(9-36)NH(2), respectively, was ~100-fold and up to 200-fold greater than that seen with the physiological signaling molecules acetylcholine and GLP-1(7-36)NH(2). Modulation of GLP-1(9-36)NH(2) was also demonstrated in ex vivo and in vivo assays of insulin secretion. This work opens up new avenues for allosteric drug discovery by directly targeting modulation of metabolites, but it also identifies a behavior that could contribute to unexpected clinical outcomes if interaction of allosteric drugs with metabolites is not part of their preclinical assessment.

  7. Brightside Academy: Pittsburgh, Pennsylvania

    Horn, Sarah

    2009-01-01

    Since its inception in 1992, Brightside Academy has been providing quality care to children six weeks to 12 years old. Operating 49 locations in Pennsylvania, Ohio, and New York, the company is committed to strengthening learners and respecting families. Currently, the organization provides early education for 6,700 children on a daily basis. 90%…

  8. Heat transfer: Pittsburgh 1987

    Lyczkowski, R.W.

    1987-01-01

    This book contains papers divided among the following sections: Process Heat Transfer; Thermal Hydraulics and Phase Change Phenomena; Analysis of Multicomponent Multiphase Flow and Heat Transfer; Heat Transfer in Advanced Reactors; General Heat Transfer in Solar Energy; Numerical Simulation of Multiphase Flow and Heat Transfer; High Temperature Heat Transfer; Heat Transfer Aspects of Severe Reactor Accidents; Hazardous Waste On-Site Disposal; and General Papers

  9. Cancer screening literature in the period 2000-2002: pointers to future research avenues.

    Moore, Malcolm A; Kunimoto, Takehiko; Tsuda, Hiroyuki

    2003-01-01

    attention, not least being the need for more comprehensive reviews across organs to allow the general reader a better understanding of the overall picture, and which avenues might best reward exploration in the future.

  10. Assisted suicide and the killing of people? Maybe. Physician-assisted suicide and the killing of patients? No: the rejection of Shaw's new perspective on euthanasia.

    McLachlan, Hugh V

    2010-05-01

    David Shaw presents a new argument to support the old claim that there is not a significant moral difference between killing and letting die and, by implication, between active and passive euthanasia. He concludes that doctors should not make a distinction between them. However, whether or not killing and letting die are morally equivalent is not as important a question as he suggests. One can justify legal distinctions on non-moral grounds. One might oppose physician-assisted suicide and active euthanasia when performed by doctors on patients whether or not one is in favour of the legalisation of assisted suicide and active euthanasia. Furthermore, one can consider particular actions to be contrary to appropriate professional conduct even in the absence of legal and ethical objections to them. Someone who wants to die might want only a doctor to kill him or to help him to kill himself. However, we are not entitled to everything that we want in life or death. A doctor cannot always fittingly provide all that a patient wants or needs. It is appropriate that doctors provide their expert advice with regard to the performance of active euthanasia but they can and should do so while, qua doctors, they remain hors de combat.

  11. Palaeointensity Results from 1951 and 1995 Lava Flows, Fogo, Cape Verde: A Comparison between Thellier and LTD-DHT Shaw Methods

    Brown, M. C.; Cropsey, J.; Bowles, J. A.; Feinberg, J. M.

    2009-12-01

    As part of an ongoing effort to link the success rate of palaeointensity experiments to specific rock magnetic properties, we present new palaeointensity results from basaltic lavas erupted in 1951 and 1995 on the island of Fogo, Cape Verde. Both Thellier and LTD-DHT Shaw palaeointensity experiments were used to estimate the historical field strength. The intensity of the field during these eruptions is constrained by data from the Mbour geomagnetic observatory (Senegal) and IGRF10. In 1951, the magnetic field intensity at Fogo was approximately 33.8 µT during the eruption of three distinct surface flows, covering approximately 14 km2. The field intensity was approximately 32.5 µT during a 1995 eruption of one large flow that extends 4 km2 across the caldera floor. Different volcanic textures were sampled from multiple sites within both the 1951 and 1995 lava flows, including glass-rich pahoehoe and aa flows, highly vesicular flows, and massive non-vesicular lava. Detailed rock magnetic measurements demonstrate that each site and texture displays distinctively different rock magnetic properties. We assess possible links between the outcome of the Thellier and LTD-DHT palaeointensity experiments and the distribution of magnetic domain states, average oxidation state, and laboratory induced alteration.

  12. Results of the radiological survey at Allied Bendix Aerospace Corporation, Industrial and Williams Avenues, Teterboro, New Jersey (TJ002)

    Foley, R.D.; Floyd, L.M.

    1989-02-01

    A radiological survey of the commercial property at Industrial and Williams Avenues, Teterboro, New Jersey, was conducted on November 17--18, 1986. Samples of the soil surface were taken for further analyses during this time. Prior to 1976, Bendix was licensed by the Nuclear Regulatory Commission to use thorium in an on-site Navy/Bendix process. 4 refs., 3 figs., 4 tabs

  13. Noninvasive k3 estimation method for slow dissociation PET ligands: application to [11C]Pittsburgh compound B.

    Sato, Koichi; Fukushi, Kiyoshi; Shinotoh, Hitoshi; Shimada, Hitoshi; Hirano, Shigeki; Tanaka, Noriko; Suhara, Tetsuya; Irie, Toshiaki; Ito, Hiroshi

    2013-11-16

    Recently, we reported an information density theory and an analysis of three-parameter plus shorter scan than conventional method (3P+) for the amyloid-binding ligand [11C]Pittsburgh compound B (PIB) as an example of a non-highly reversible positron emission tomography (PET) ligand. This article describes an extension of 3P + analysis to noninvasive '3P++' analysis (3P + plus use of a reference tissue for input function). In 3P++ analysis for [11C]PIB, the cerebellum was used as a reference tissue (negligible specific binding). Fifteen healthy subjects (NC) and fifteen Alzheimer's disease (AD) patients participated. The k3 (index of receptor density) values were estimated with 40-min PET data and three-parameter reference tissue model and were compared with that in 40-min 3P + analysis as well as standard 90-min four-parameter (4P) analysis with arterial input function. Simulation studies were performed to explain k3 biases observed in 3P++ analysis. Good model fits of 40-min PET data were observed in both reference and target regions-of-interest (ROIs). High linear intra-subject (inter-15 ROI) correlations of k3 between 3P++ (Y-axis) and 3P + (X-axis) analyses were shown in one NC (r2 = 0.972 and slope = 0.845) and in one AD (r2 = 0.982, slope = 0.655), whereas inter-subject k3 correlations in a target region (left lateral temporal cortex) from 30 subjects (15 NC + 15 AD) were somewhat lower (r2 = 0.739 and slope = 0.461). Similar results were shown between 3P++ and 4P analyses: r2 = 0.953 for intra-subject k3 in NC, r2 = 0.907 for that in AD and r2 = 0.711 for inter-30 subject k3. Simulation studies showed that such lower inter-subject k3 correlations and significant negative k3 biases were not due to unstableness of 3P++ analysis but rather to inter-subject variation of both k2 (index of brain-to-blood transport) and k3 (not completely negligible) in the reference region. In [11C]PIB, the applicability of 3

  14. Archeointensity study on baked clay samples taken from the reconstructed ancient kiln: implication for validity of the Tsunakawa-Shaw paleointensity method

    Yamamoto, Yuhji; Torii, Masayuki; Natsuhara, Nobuyoshi

    2015-05-01

    In 1972, a reconstruction experiment of a kiln had been done to reproduce an excavated kiln of the seventh century in Japan. Baked clay samples were taken from the floor surface and -20 cm level, and they have been stored after determinations of the paleomagnetic directions by partial alternating field demagnetizations. We recently applied the Tsunakawa-Shaw method to the samples to assess how reliable archeointensity results are obtained from the samples. A suite of the rock magnetic experiments and the scanning electron microscope observations elucidate that dominant magnetic carriers of the floor surface samples are Ti-poor titanomagnetite grains in approximately 10 nm size with single-domain and/or super-paramagnetic states, whereas contributions of multi-domain grains seem to be relatively large for the -20-cm level samples. From the floor surface samples, six out of the eight successful results were obtained and they give an average of 47.3 μT with a standard deviation of 2.2 μT. This is fairly consistent with the in situ geomagnetic field of 46.4 μT at the time of the reconstruction. They are obtained with a built-in anisotropy correction using anhysteretic remanent magnetization and without any cooling rate corrections. In contrast, only one out of four was successful from the -20-cm level samples. It yields an archeointensity of 31.6 μT, which is inconsistent with the in situ geomagnetic field. Considering from the in situ temperature record during the firing of the kiln and the unblocking temperature spectra of the samples, the floor surface samples acquired full thermoremanent magnetizations (TRMs) as their natural remanent magnetizations whereas the -20-cm level samples only acquired partial TRMs, and these differences probably cause the difference in the archeointensity results between the two sample groups. For archeointensity researches, baked clay samples from a kiln floor are considered to be ideal materials.

  15. Lutzomyia wellcomei Fraiha, Shaw & Lainson (Diptera, Psychodidae, Phlebotominae em Fragmento de Mata Atlântica do Rio Grande do Norte, Nordeste do Brasil

    Marcos Paulo Gomes Pinheiro

    2013-12-01

    Resumo. As leishmanioses podem afetar seres humanos e animais nas formas visceral e tegumentar. A forma tegumentar tem sido associada, entre outras espécies, a Lutzomyia wellcomei Fraiha, Shaw & Lainson, inicialmente encontrado na região amazônica. O estudo se baseou em coletas mensais de janeiro a dezembro em um fragmento de Mata Atlântica e em um ambiente peridomiciliar, com armadilhas luminosas CDC. Esse é o primeiro estudo sistematizado sobre essa espécie no Rio Grande do Norte. Os insetos foram identificados e analisados em relação às chuvas no local. Alguns espécimes de L. wellcomei foram metalizados sob fita de carbono, visualizados e fotografados em microscópio eletrônico de varredura. A espécie mais abundante na área de mata foi Lutzomyia walkeri Newstead seguida por L. wellcomei. Do total capturado no ambiente de mata e no peridomicílio, cerca de 8% corresponde a L. wellcomei, sendo esta a espécie predominante no ambiente de mata no período chuvoso. Flebotomíneos L. wellcomei não foram capturados em ambiente peridomiciliar. Na mata essa espécie foi encontrada juntamente às espécies Lutzomyia whitmani Antunes & Coutinho e Lutzomyia intermedia Lutz & Neiva. Machos e fêmeas Lutzomyia longipalpis Lutz & Neiva foram predominantes no ambiente peridomiciliar. A análise microscópica da morfologia externa de L. wellcomei revela detalhes da cabeça de machos e fêmeas.

  16. Review of the mechanisms and therapeutic avenues for retinal and choroidal vascular dysfunctions in retinopathy of prematurity.

    Rivera, José Carlos; Madaan, Ankush; Zhou, Tianwei Ellen; Chemtob, Sylvain

    2016-12-01

    Retinopathy of prematurity (ROP) is a multifactorial disease and the main cause of visual impairment and blindness in premature neonates. The inner retina has been considered the primary region affected in ROP, but choroidal vascular degeneration and progressive outer retinal dysfunctions have also been observed. This review focuses on observations regarding neurovascular dysfunctions in both the inner and outer immature retina, the mechanisms and the neuronal-derived factors implicated in the development of ROP, as well potential therapeutic avenues for this disorder. Alterations in the neurovascular integrity of the inner and outer retina contribute to the development of ROP. ©2016 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  17. Geostatistical modeling of the gas emission zone and its in-place gas content for Pittsburgh-seam mines using sequential Gaussian simulation

    Karacan, C.O.; Olea, R.A.; Goodman, G.

    2012-01-01

    Determination of the size of the gas emission zone, the locations of gas sources within, and especially the amount of gas retained in those zones is one of the most important steps for designing a successful methane control strategy and an efficient ventilation system in longwall coal mining. The formation of the gas emission zone and the potential amount of gas-in-place (GIP) that might be available for migration into a mine are factors of local geology and rock properties that usually show spatial variability in continuity and may also show geometric anisotropy. Geostatistical methods are used here for modeling and prediction of gas amounts and for assessing their associated uncertainty in gas emission zones of longwall mines for methane control.This study used core data obtained from 276 vertical exploration boreholes drilled from the surface to the bottom of the Pittsburgh coal seam in a mining district in the Northern Appalachian basin. After identifying important coal and non-coal layers for the gas emission zone, univariate statistical and semivariogram analyses were conducted for data from different formations to define the distribution and continuity of various attributes. Sequential simulations performed stochastic assessment of these attributes, such as gas content, strata thickness, and strata displacement. These analyses were followed by calculations of gas-in-place and their uncertainties in the Pittsburgh seam caved zone and fractured zone of longwall mines in this mining district. Grid blanking was used to isolate the volume over the actual panels from the entire modeled district and to calculate gas amounts that were directly related to the emissions in longwall mines.Results indicated that gas-in-place in the Pittsburgh seam, in the caved zone and in the fractured zone, as well as displacements in major rock units, showed spatial correlations that could be modeled and estimated using geostatistical methods. This study showed that GIP volumes may

  18. Natural convection heat transfer in an anisotropic porous cavity heated from the side. 2nd Report. experiment by hele-shaw cell; Tosuiritsu ni ihosei wo yusuru howa takoshitsu sonai no sokuho kanetsu ni yoru shizen tairyu netsu dentatsu. 2. Hele shaw cell ni yoru jikken

    Kimura, S; Okajima, A; Kiwata, T [Kanazawa University, Ishikawa (Japan). Faculty of Engineering

    2000-11-25

    Natural convection heat transfer and flow structure in an anisotropic porous medium of square cavity saturated with Boussinesq fluid has been studied experimentally using a Hele-Shaw cell. The permeability ratio defined by K=K{sub y}/K{sub x} was put to three different values; 0.4, 1 and 2.5. The convection patterns at three different permeability ratios are visualized for several different Rayleigh numbers by the pH indicator method. When K is 0.25, the visualized flow is mainly in the vertical direction. On the contrary for K=4 the convecting flow is in the horizontal direction. The average heat transfer coefficients are also measured, and the corresponding Nusselt number are plotted as a function of K. It is found that the corresponding Nusselt numbers are scaled with (KRa){sup 1/2}. The experimental results of flow pattern and heat transfer are accord with those obtained by our previous theory. (author)

  19. Results of the radiological survey at Sumitomo Machinery Corporation of America, 7 Malcolm Avenue, Teterboro, New Jersey (TJ001)

    Foley, R.D.; Floyd, L.M.

    1989-02-01

    A radiological survey of the commercial property at 7 Malcolm Avenue, Teterboro, New Jersey, was conducted on November 12--20, 1986. Samples of the soil surface were taken for further analyses during this time. Conversations with property owners revealed that originally this site was part of a single property of approximately 107 acres owned entirely by the Bendix Aerospace Corporation. During this period of total property ownership, Bendix was licensed by the Nuclear Regulatory Commission to use thorium in on-site Navy/Bendix process. Around 1976, the property was subdivided into three parcels, and one parcel of about 7 acres was purchased by Sumitomo Corporation. 5 refs., 3 figs., 5 tabs

  20. Results of the radiological survey at the Niagara-Mohawk property, Railroad Avenue, Colonie, New York (AL218)

    Marley, J.L.; Carrier, R.F.

    1987-12-01

    A number of properties in the Albany/Colonie area have been identified as being potentially contaminated with uranium originating from the former National Lead Company's uranium forming plant in Colonie, New York. The Niagara-Mohawk property on Railroad Avenue in Colonie, New York, was the subject of a radiological investigation initiated June 11, 1987. This commercial property is an irregularly shaped lot partially occupied by an electric power substation and associated transmission lines. Portions of the property that were swampy and heavily vegetated were inaccessible to the survey team. There are no buildings on the property. A diagram showing the approximate boundaries and the 15-m grid network established for measurements on the property is shown. The lot included in the radiological survey was /approximately/45 m wide by 246 m deep. Two views of the property are shown. 13 refs., 6 figs., 4 tabs

  1. Superfund Record of Decision (EPA Region 9): Nineteenth Avenue Landfill, Phoenix, AZ. (First remedial action), September 1989. Final report

    1989-01-01

    The 213-acre Nineteenth Avenue Landfill is in an industrial area of Maricopa County, Phoenix, Arizona. State permitted landfill operations were conducted from 1957 to 1979 during which time approximately nine million cubic yards of municipal refuse, solid and liquid industrial wastes, and some medical wastes and materials containing low levels of radioactivity were deposited in the landfill. The State ordered the landfill closed in 1979 due to the periodic inundation of the landfill by flood waters from the Salt River Channel. Subsequently, the city covered the site with fill, stockpiled soil for final capping, installed ground water monitoring wells, built berms around the landfill, and installed a methane gas collection system. The remedial action is designed to mitigate threats resulting from flooding of the landfill, which has occurred intermittently since 1965. The primary contaminants of concern in the soil/refuse include VOCs such as toluene and xylenes

  2. Results of the radiological survey at Route 17(S) and Becker Avenue, Rochelle Park, New Jersey (RJ001)

    Foley, R.D.; Carrier, R.F.

    1989-11-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The surveys typically include direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this commercial property at Route 17(S) and Becker Avenue, Rochelle Park, New Jersey (RJ001), was conducted in 1986. Measurements taken at the commercial property located at Route 17(S) and Becker Avenue indicate slightly elevated gamma exposure rates in three areas of the parking lot. Although results of analysis of the asphalt disclosed radionuclide concentrations in excess of the applicable criterion, their presence is due to naturally radioactive substances in asphalt patching materials and is not associated with material from the MCW site. Therefore, it is recommended that this site be eliminated from consideration for inclusion in the DOE remedial action program. 5 refs., 2 figs., 3 tabs

  3. Meal from tilapia filleting industrial waste in the feed of the bullfrog tadpoles (Rana Catesbeiana Shaw, 1802/ Inclusão de farinha de resíduos da indústria de filetagem de tilápias na alimentação de girinos de rã-touro (Rana Catesbeiana Shaw,1802

    Cleiton Manske

    2007-08-01

    Full Text Available The objective of this experiment was to evaluate the inclusion of meal of tilapia industrial waster in bullfrog tadpoles’ diets (Rana Catesbeina Shaw, 1802. Two hundred fifty tadpoles with initial weight and length of 0,18 ± 0,05g and 2,50 ± 0,18 centimeters were used, respectively, they were used and distributed in 25 aquariums of 30 liter each in a complete randomized design with five treatments and five repetitions. The tadpoles were fed four times a day with diets containing 0, 5, 10 and 15% of inclusion of tilapia filleting and another diet with 0% of supplemented tilapia filleting with synthetic methionine, being supplied four times a day at ease. The experiment period was 30 days. The diets with tilapia filleting inclusion and methionine supplementation did not have influence in the final weight and length averages, feed survival and conversion of bullfrog tadpoles. It cam be used until 15% of tilapia filleting inclusion in the bullfrog tadpoles food. The synthetic methionine supplementation in diets for bullfrog tadpoles is not necessary in diets with levels over 0,47% of the total methionine.Este experimento objetivou avaliar a inclusão da farinha de resíduos de filetagem de tilápias (FT em rações para girinos de rã-touro (Rana Catesbeina Shaw,1802. Foram utilizados 250 girinos com peso e comprimento inicial de 0,18 ± 0,05g e 2,50 ± 0,18 cm, respectivamente, distribuídos em 25 aquários de 30 L cada, em um delineamento inteiramente casualizado com cinco tratamentos e cinco repetições. Os girinos foram alimentados quatro vezes ao dia, com rações contendo 0, 5, 10, 15% de inclusão de FT e outra ração com 0% de FT suplementada com metionina sintética, sendo fornecidas quatro vezes ao dia a vontade. O período do experimento foi de 30 dias. As rações com inclusão de FT e suplementação de metionina não influenciaram nas médias de peso final, comprimento final, sobrevivência e conversão alimentar dos girinos de r

  4. Johnston Avenue Solar Project

    Schrayer, David [Isles, Inc., Trenton, NJ (United States)

    2017-08-22

    DOE awarded funds to support a demonstration project to illustrate how access to solar power and green roof systems could improve building performance and long-term outcomes for the building owner and multiple nonprofit tenants housed in the building. Since being placed in service the solar PV system has saved approximately $1,000 per month in energy costs. The green roof has added to this benefit by naturally cooling the building and has helped reduce local road flooding by retaining storm water. These elements have improved the quality of life in the low-income community in which the building is located by allowing social service organizations to focus more of their resources on programs and job creation.

  5. Effect of Using an Indoor Air Quality Sensor on Perceptions of and Behaviors Toward Air Pollution (Pittsburgh Empowerment Library Study): Online Survey and Interviews.

    Wong-Parodi, Gabrielle; Dias, M Beatrice; Taylor, Michael

    2018-03-08

    Air quality affects us all and is a rapidly growing concern in the 21st century. We spend the majority of our lives indoors and can be exposed to a number of pollutants smaller than 2.5 microns (particulate matter, PM 2.5 ) resulting in detrimental health effects. Indoor air quality sensors have the potential to provide people with the information they need to understand their risk and take steps to reduce their exposure. One such sensor is the Speck sensor developed at the Community Robotics, Education and Technology Empowerment Lab at Carnegie Mellon University. This sensor provides users with continuous real-time and historical PM 2.5 information, a Web-based platform where people can track their PM 2.5 levels over time and learn about ways to reduce their exposure, and a venue (blog post) for the user community to exchange information. Little is known about how the use of such monitors affects people's knowledge, attitudes, and behaviors with respect to indoor air pollution. The aim of this study was to assess whether using the sensor changes what people know and do about indoor air pollution. We conducted 2 studies. In the first study, we recruited 276 Pittsburgh residents online and through local branches of the Carnegie Library of Pittsburgh, where the Speck sensor was made available by the researchers in the library catalog. Participants completed a 10- to 15-min survey on air pollution knowledge (its health impact, sources, and mitigation options), perceptions of indoor air quality, confidence in mitigation, current behaviors toward air quality, and personal empowerment and creativity in the spring and summer of 2016. In our second study, we surveyed 26 Pittsburgh residents in summer 2016 who checked out the Speck sensor for 3 weeks on the same measures assessed in the first study, with additional questions about the perception and use of the sensor. Follow-up interviews were conducted with a subset of those who used the Speck sensor. A series of paired t

  6. Influence of avenue-trees on air quality at the urban neighborhood scale. Part II: traffic pollutant concentrations at pedestrian level.

    Gromke, Christof; Blocken, Bert

    2015-01-01

    Flow and dispersion of traffic-emitted pollutants were studied in a generic urban neighborhood for various avenue-tree layouts by employing 3D steady RANS simulations with the realizable k-ε turbulence model. In comparison to the tree-free situation quantitative and qualitative changes with flow reversal in the wind field were observed. Low to moderate increases (pollutant concentration were found at pedestrian level. An approximately 1% increase in the neighborhood-averaged concentration was obtained with each percent of the street canyon volumes being occupied by vegetation for occupation fractions between 4 and 14%. The overall pattern of concentration changes relative to the tree-free situation was similar for all avenue-tree layouts. However, pronounced locally restricted decreases or increases in concentration (-87 to +1378%) occurred. The results indicate the necessity to account for existing or planned avenue-trees in neighborhood scaled is dispersion studies. Their consideration is prerequisite for reliable urban air quality assessment.

  7. Results of the radiological verification survey of the partial remediation at 90 Avenue C, Lodi, New Jersey (LJ079V)

    Foley, R.D.; Johnson, C.A.

    1994-02-01

    The property at 90 Avenue C, Lodi, New Jersey is one of the vicinity properties of the former Maywood Chemical Works, Maywood, New Jersey designated for remedial action by the US Department of Energy (DOE). In July 1991, Bechtel National, Inc. performed a partial remedial action on this property. At the request of DOE, a team from Oak Ridge National Laboratory conducted an independent radiological verification survey in July, 1991 at this site. The purpose of the verification survey was to ensure the effectiveness of remedial actions performed within FUSRAP and to confirm the site's compliance with DOE guidelines. The radiological survey included surface gamma scans indoors and outdoors, ground-level beta-gamma measurements, and systematic and biased soil and material sampling. Results of the verification survey demonstrated that all radiological measurements on the portions of the property that had been remediated were within DOE guidelines. However, there still remains a portion of the property to be remediated that is not covered by this verification survey

  8. The design and construction of large diameter pre-filter packed recovery wells at the Ninth Avenue Superfund Site

    Lombardo, S.L.; Maley, T.J.; Bono, B.A.

    1992-01-01

    Large diameter groundwater/oil recovery wells were installed in an unconfined sand aquifer at the Ninth Avenue Superfund Site in Gary, Indiana. To assure adequate filter packs, prefilter packed groundwater/oil recovery wells were selected to minimize silting by using appropriate screen slot size and filter pack. A properly sized filter pack was necessary to prevent the formation material from entering the well. During field drilling operations, open-quotes having sandsclose quotes and silting of existing wells were encountered. By using sieve analyses of the native aquifer soil, described by Driscoll (1989), the filter pack and screen slot size were selected. Prefilter packed well screens were selected for this site to assure the presence of a uniform filter pack, thus minimizing siltation in the wells. A prefilter packed well screen consists of a double screen with the interstitial space filled with granular filter pack material designed specifically for site conditions. These wells provide the adequate filter pack without the need to add additional filter pack material outside the well screen. Wells were installed using 12 1/4 inch ID hollow stem augers. This methodology is EPA-approved, expeditious, and inexpensive. Level B personal protective equipment was required during installation. Therefore, the advantages of hollow stem drilling include short drilling time and no circulation fluids. The 14 recovery wells were successfully installed in 14 days using the hollow stem auger drilling technique. Observations during well development revealed little or no silt present in purged groundwater

  9. Radiological assessment and remedial action report for the ''Son of Lansdowne'' property, 186 North Lansdowne Avenue, Lansdowne, Pennsylvania

    Smith, W.H.; Wynveen, R.A.

    1987-08-01

    This document reports the results of a radiological assessment and remedial action program conducted by Argonne National Laboratory personnel at a radioactively contaminated private residence in Lansdowne, Pennsylvania. The program was conducted on the residence at 186 Lansdowne Avenue. The survey conducted by the ANL personnel indicated that several dozen areas or spots of contamination were present on all floors and the basement of the three-story house. Contamination was found on furniture, carpeting, walls, floors, woodwork, and ceilings. Remedial action undertaken to remove the contamination ranged from scrubbing, to scraping, to shaving of wood, to removal and disposal of items and material that could not be adequately decontaminated. Outdoors, contaminated soil was removed from the backyard, and the driveway was dug up so the contaminated subsurface material could be removed. The remedial action generated quantities of radioactive waste, including four 55-gallon drums and one M-III bin (120 ft 3 ) containing floor tile, concrete, personal items, furniture, floor scrapings, vermiculite absorbed scrub water, and other items. In addition, there were 24 M-III bins containing approximately 112 tons of contaminated soil and rock from the two contaminated areas in the backyard and from the contaminated subsurface of the driveway. 2 refs., 39 figs., 12 tabs

  10. Using New Mode Choice Model Nesting Structures to Address Emerging Policy Questions: A Case Study of the Pittsburgh Central Business District

    Zulqarnain H. Khattak

    2017-11-01

    Full Text Available As transportation activities affect a region’s environmental quality, knowing why individuals prefer certain modes can help a region make judicious transportation investments. Using a nested logit model, this paper studies the behavior of commuters to downtown Pittsburgh who use auto, bus, light rail, walking, and biking. Although statistical measures influence the selection of a nesting structure, another criterion for model selection is the policy questions such models inform. Hence this paper demonstrates how an alternative model structure allows planners to consider new policy questions. For example, how might a change in parking fee affect greenhouse gas emission (GHGs? The proposed model showed that a 5%, 10% and 15% increase in parking cost reduces GHGs by 7.3%, 9% and 13.2%, respectively, through increasing carpoolers’ mode share. Because the proposed model forecasts mode choices of certain groups of travelers with higher accuracy (compared to an older model that did not consider the model selection criteria presented here, the proposed model strengthens policymakers’ ability to consider environmental impacts of interest to the region (in this case, GHGs. The paper does not suggest that one nesting structure is always preferable; rather the nesting structure must be chosen with the policy considerations in mind.

  11. Concussion is Treatable: Statements of Agreement from the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting held in Pittsburgh, October 15–16, 2015

    Collins, Michael W.; Kontos, Anthony P.; Okonkwo, David O.; Almquist, Jon; Bailes, Julian; Barisa, Mark; Bazarian, Jeffrey; Bloom, O. Josh; Brody, David; Cantu, Robert; Cardenas, Javier; Clugston, Jay; Cohen, Randall; Echemendia, Ruben; Elbin, R.J.; Ellenbogen, Richard; Fonseca, Janna; Gioia, Gerard; Guskiewicz, Kevin; Heyer, Robert; Hotz, Gillian; Iverson, Grant L.; Jordan, Barry; Manley, Geoffrey; Maroon, Joseph; McAllister, Thomas; McCrea, Michael; Mucha, Anne; Pieroth, Elizabeth; Podell, Kenneth; Pombo, Matthew; Shetty, Teena; Sills, Allen; Solomon, Gary; Thomas, Danny G.; Valovich McLeod, Tamara C.; Yates, Tony; Zafonte, Ross

    2016-01-01

    Background Conventional management for concussion involves prescribed rest and progressive return to activity. Recent evidence challenges this notion and suggests that active approaches may be effective for some patients. Previous concussion consensus statements provide limited guidance regarding active treatment. Objective To describe the current landscape of treatment for concussion and provide summary agreements related to treatment in order to assist clinicians in the treatment of concussion. Methods On October 14–16, 2015, the Targeted Evaluation & Active Management (TEAM) Approaches To Treating Concussion meeting was convened in Pittsburgh, Pennsylvania, USA. 37 concussion experts from neuropsychology, neurology, neurosurgery, sports medicine, physical medicine and rehabilitation, physical therapy, athletic training, and research, and 12 individuals representing sport, military, and public health organizations attended the meeting. The 37 experts indicated their agreement on a series of statements using an audience response system clicker device. Results A total of 16 statements of agreement were supported covering: 1) Summary of the Current Approach to Treating Concussion, 2) Heterogeneity and Evolving Clinical Profiles of Concussion, 3) Targeted Evaluation and Active Management Approach to Concussion Treatment: Specific Strategies, and 4) Future Directions: A Call to Research. Support (ie, response of agree or somewhat agree) for the statements ranged from to 97–100%. Conclusion Concussions are characterized by diverse symptoms and impairments and evolving clinical profiles; recovery varies based on modifying factors, injury severity, and treatments. Active and targeted treatments may enhance recovery following concussion. Research is needed on concussion clinical profiles, biomarkers, and the effectiveness and timing of treatments. PMID:27741219

  12. 77 FR 27082 - StarTek USA, Inc., 244 Dundee Avenue, Greeley, CO; StarTek USA, Inc., 1250 H Street, Greeley, CO...

    2012-05-08

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,850; TA-W-74,850A] StarTek USA, Inc., 244 Dundee Avenue, Greeley, CO; StarTek USA, Inc., 1250 H Street, Greeley, CO; Amended... workers and former workers of StarTek USA, Inc., Greeley, Colorado. The Department's notice of...

  13. Evaluation of numerical flow and dispersion simulations for street canyons with avenue-like tree planting by comparison with wind tunnel data

    Gromke, C.B.; Buccolieri, R.; Sabatino, Di S.; Ruck, B.

    2008-01-01

    Flow and traffic-originated pollutant dispersion in an urban street canyon with avenue-like tree planting have been studied by means of wind tunnel and CFD investigations. The study comprises tree planting of different crown porosity, planted in two rows within a canyon of street width to building

  14. Amyloid imaging in cognitively normal older adults: comparison between {sup 18}F-flutemetamol and {sup 11}C-Pittsburgh compound B

    Adamczuk, Katarzyna; Schaeverbeke, Jolien; Neyens, Veerle; Dupont, Patrick [KU Leuven, Laboratory for Cognitive Neurology, Leuven (Belgium); Leuven Institute of Neuroscience and Disease, Alzheimer Research Centre KU Leuven, Leuven (Belgium); Nelissen, Natalie [KU Leuven, Laboratory for Cognitive Neurology, Leuven (Belgium); Oxford University, Department of Psychiatry, Oxford (United Kingdom); Vandenbulcke, Mathieu [University Hospitals Leuven, Old Age Psychiatry Department, Leuven (Belgium); Goffin, Karolien [KU Leuven and University Hospitals Leuven, Nuclear Medicine and Molecular Imaging Department, Leuven (Belgium); Lilja, Johan [GE Healthcare, Uppsala (Sweden); Department of Surgical Sciences, Radiology, Uppsala University Hospital, Uppsala University, Uppsala (Sweden); Hilven, Kelly [KU Leuven, Laboratory for Neuroimmunology, Leuven (Belgium); Laere, Koen van [Leuven Institute of Neuroscience and Disease, Alzheimer Research Centre KU Leuven, Leuven (Belgium); KU Leuven and University Hospitals Leuven, Nuclear Medicine and Molecular Imaging Department, Leuven (Belgium); Vandenberghe, Rik [KU Leuven, Laboratory for Cognitive Neurology, Leuven (Belgium); Leuven Institute of Neuroscience and Disease, Alzheimer Research Centre KU Leuven, Leuven (Belgium); University Hospitals Leuven, Neurology Department, Leuven (Belgium)

    2016-01-15

    Preclinical, or asymptomatic, Alzheimer's disease (AD) refers to the presence of positive AD biomarkers in the absence of cognitive deficits. This research concept is being applied to define target populations for clinical drug development. In a prospective community-recruited cohort of cognitively intact older adults, we compared two amyloid imaging markers within subjects: {sup 18}F-flutemetamol and {sup 11}C-Pittsburgh compound B (PIB). In 32 community-recruited cognitively intact older adults aged between 65 and 80 years, we determined the concordance between binary classification based on {sup 18}F-flutemetamol versus {sup 11}C-PIB according to semiquantitative assessment (standardized uptake value ratio in composite cortical volume, SUVR{sub comp}) and, alternatively, according to visual reads. We also determined the correlation between {sup 18}F-flutemetamol and {sup 11}C-PIB SUVR and evaluated how this was affected by the reference region chosen (cerebellar grey matter versus pons) and the use of partial volume correction (PVC) in this population. Binary classification based on semiquantitative assessment was concordant between {sup 18}F-flutemetamol and {sup 11}C-PIB in 94 % of cases. Concordance of blinded binary visual reads between tracers was 84 %. The Spearman correlation between {sup 18}F-flutemetamol and {sup 11}C-PIB SUVR{sub comp} with cerebellar grey matter as reference region was 0.84, with a slope of 0.98. Correlations in neocortical regions were significantly lower with the pons as reference region. PVC improved the correlation in striatum and medial temporal cortex. For the definition of preclinical AD based on {sup 18}F-flutemetamol, concordance with {sup 11}C-PIB was highest using semiquantitative assessment with cerebellar grey matter as reference region. (orig.)

  15. Design and Feasibility Assessment of a Retrospective Epidemiological Study of Coal-Fired Power Plant Emissions in the Pittsburgh Pennsylvania Region

    Richard A. Bilonick; Daniel Connell; Evelyn Talbott; Jeanne Zborowski; Myoung Kim

    2006-12-20

    Eighty-nine (89) percent of the electricity supplied in the 35-county Pittsburgh region (comprising parts of the states of Pennsylvania, Ohio, West Virginia, and Maryland) is generated by coal-fired power plants making this an ideal region in which to study the effects of the fine airborne particulates designated as PM{sub 2.5} emitted by the combustion of coal. This report demonstrates that during the period from 1999-2006 (1) sufficient and extensive exposure data, in particular samples of speciated PM{sub 2.5} components from 1999 to 2003, and including gaseous co-pollutants and weather have been collected, (2) sufficient and extensive mortality, morbidity, and related health outcomes data are readily available, and (3) the relationship between health effects and fine particulates can most likely be satisfactorily characterized using a combination of sophisticated statistical methodologies including latent variable modeling (LVM) and generalized linear autoregressive moving average (GLARMA) time series analysis. This report provides detailed information on the available exposure data and the available health outcomes data for the construction of a comprehensive database suitable for analysis, illustrates the application of various statistical methods to characterize the relationship between health effects and exposure, and provides a road map for conducting the proposed study. In addition, a detailed work plan for conducting the study is provided and includes a list of tasks and an estimated budget. A substantial portion of the total study cost is attributed to the cost of analyzing a large number of archived PM{sub 2.5} filters. Analysis of a representative sample of the filters supports the reliability of this invaluable but as-yet untapped resource. These filters hold the key to having sufficient data on the components of PM{sub 2.5} but have a limited shelf life. If the archived filters are not analyzed promptly the important and costly information they

  16. Evaluation of numerical flow and dispersion simulations for street canyons with avenue-like tree planting by comparison with wind tunnel data

    Gromke, CB Christof; Buccolieri, R; Sabatino, S Di; Ruck, B

    2008-01-01

    Abstract: Flow and traffic-originated pollutant dispersion in an urban street canyon with avenue-like tree planting have been studied by means of wind tunnel and CFD investigations. The study comprises tree planting of different crown porosity, planted in two rows within a canyon of street width to building height ratio W/H = 2 and street length to building height ratio L/H = 10 exposed to a perpendicular approaching boundary layer flow. Numerical simulations have been performed with...

  17. International telepathology consultation: Three years of experience between the University of Pittsburgh Medical Center and KingMed Diagnostics in China

    Chengquan Zhao

    2015-01-01

    Full Text Available Background: Telepathology is increasingly being employed to support diagnostic consultation services. Prior publications have addressed technology aspects for telepathology, whereas this paper will address the clinical telepathology experience of KingMed Diagnostics, the largest independent pathology medical laboratory in China. Beginning in 2012 the University of Pittsburgh Medical Center (UPMC and KingMed Diagnostics partnered to establish an international telepathology consultation service. Materials and Methods: This is a retrospective study that summarizes the telepathology experience and diagnostic consultation results between UPMC and KingMed over a period of 3 years from January 2012 to December 2014. Results: A total of 1561 cases were submitted for telepathology consultation including 144 cases in 2012, 614 cases in 2013, and 803 in 2014. Most of the cases (61.4% submitted were referred by pathologists, 36.9% by clinicians, and 1.7% by patients in China. Hematopathology received the most cases (23.7%, followed by bone/soft tissue (21.0% and gynecologic/breast (20.2% subspecialties. Average turnaround time (TAT per case was 5.4 days, which decreased from 6.8 days in 2012 to 5.0 days in 2014. Immunostains were required for most of the cases. For some difficult cases, more than one round of immunostains was needed, which extended the TAT. Among 855 cases (54.7% where a primary diagnosis or impression was provided by the referring local hospitals in China, the final diagnoses rendered by UPMC pathologists were identical in 25.6% of cases and significantly modified (treatment plan altered in 50.8% of cases. Conclusion: These results indicate that international telepathology consultation can significantly improve patient care by facilitating access to pathology expertise. The success of this international digital consultation service was dependent on strong commitment and support from leadership, information technology expertise, and

  18. ÍNDICE DA QUALIDADE DO SONO DE PITTSBURGH PARA USO NA REABILITAÇÃO CARDIOPULMONAR E METABÓLICA

    Pablo Antonio Bertasso de Araujo

    2015-12-01

    Full Text Available Introdução A qualidade do sono constitui-se em parâmetro relevante na avaliação da saúde em geral, sendo um fator relevante na determinação do risco das doenças cardiovasculares. Objetivo Validar a versão adaptada do questionário de avaliação do Índice de Qualidade do Sono de Pittsburgh (PSQI para uso em programas de reabilitação cardiopulmonar e metabólica (RCPM. Métodos Estudo descritivo transversal realizado com 101 pacientes de ambos os sexos, com média de idade de 66,05 (± 13,9 anos. Para a análise estatística foi considerado intervalo de confiança de 95% e valor de significância p <0,05; para a análise de consistência interna foi utilizado o coeficiente de alfa de Cronbach e para a análise da relação entre componentes e itens com o escore total do questionário foi utilizado o coeficiente de correlação de Spearman. Resultados Todos os componentes do questionário apresentaram boa consistência interna com valor de 0,72. Os componentes que mais se relacionaram com o escore total foram "duração do sono" e "qualidade subjetiva do sono", sendo que o componente que menos se relacionou foi "alterações do sono". Dentre os itens a variação foi de 0,584 no item "durante a última semana, em geral, como você classificaria a qualidade do seu sono?", até -0,611 no item "durante a última semana, quantas horas você conseguia dormir durante a noite?". Foi possível observar que os itens "tossir ou roncar muito alto" e "frequência para dificuldades do sono por outras razões" não apresentaram correlação com o escore total do questionário. Conclusão A versão adaptada do PSQI mostrou-se válida para ser utilizada na avaliação do sono em programas de RCPM.

  19. Description of Eimeria motelo sp. n. (Apicomplexa: Eimeriidae from the yellow footed tortoise, Geochelone denticulata (Chelonia: Testudinidae, and replacement of Eimeria carinii Lainson, Costa & Shaw, 1990 by Eimeria lainsoni nom. nov.

    Lada Hurková

    2000-12-01

    Full Text Available Eimeria motelo sp. n. is described from faeces of the yellow-footed tortoise, Geochelone denticulata (L.. Oocysts are irregularly ellipsoidal or cylindrical, with slightly expressed lobed protrusions and irregularities at the poles, possibly caused by wrinkling of the oocyst wall, 17 (15-19 × 9.4 (8.5-11 µm, shape index (length/width being 1.81 (1.45-2. The oocyst wall is smooth, single-layered, 0.5 µm thick with no micropyle. There are no polar bodies. Sporocysts are ellipsoidal, 8.9 (7.5-10 × 4.4 (4-5 µm, shape index 2.03 (1.7-2.5. A sporocyst residuum is present, composed of many granules of irregular size. The sporozoites are elongate, lying lengthwise in the sporocysts. Comparison with other species of the genus Eimeria parasitising members of family Testudinidae indicates that the presently described coccidium represents a new species. The name of Eimeria carinii Lainson, Costa & Shaw, 1990 is found to be preoccupied by a homonym, Eimeria carinii Pinto 1928 given to a coccidium from Rattus norvegicus. Therefore, it is replaced by Eimeria lainsoni nom. nov.

  20. Use of the X-Ray diffraction technique in the assessment of air quality at Presidente Antônio Carlos Avenue, Belo Horizonte

    Cesar, Raisa Helena Sant’Ana; Barreto, Alberto Avelar; Cruz, Ananda Borjaille; Barbosa, João Batista Santos, E-mail: raisa.cesar@cdtn.br, E-mail: aab@cdtn.br, E-mail: abc@cdtn.br, E-mail: jbsb@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte/MG (Brazil); Silva, Igor Felipe Moura, E-mail: igorfelipedx@ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Energia Nuclear

    2017-07-01

    Belo Horizonte is the sixth most populous city in Brazil, has the third largest fleet of vehicles and it is close to large mineralogical reserves, such the Quadrilátero Ferrífero. These factors, coupled with the industrial growth and civil construction, raise questions about society regarding ambient air quality. A historically problematic contaminant is the particulate matter (PM), a mixture of solid and liquid particles in suspension that generate environmental damage and human health. These particles can cause from a simple infection to death, being their dimension a fundamental factor to evaluate the impact caused. In this context, this research investigated the air quality due to PM10 (particles less than 10 microns) in a high traffic flow of Minas Gerais capital, Presidente Antônio Carlos Avenue. This avenue is one of the main accesses to the region of Pampulha, an area of great tourist and sporting relevance of the city and has undergone works of duplication and implementation of exclusive lanes for public transport buses due to the realization of the 2014 World Cup. Involved monitoring in the avenue in the year 2014 in order to collect the PM10 present in the ambient air. The characterization of PM10 occurred with the use of the X-ray diffraction technique, one of the main tools of mineralogical characterization, due to its simplicity, speed and reliability of the obtained results. The minerals detected by the analysis were evaluated for their possible origin, generating information for the evaluation of PM10 emitting sources that are fundamental for the management of air quality in the city. (author)

  1. Use of the X-Ray diffraction technique in the assessment of air quality at Presidente Antônio Carlos Avenue, Belo Horizonte

    Cesar, Raisa Helena Sant’Ana; Barreto, Alberto Avelar; Cruz, Ananda Borjaille; Barbosa, João Batista Santos; Silva, Igor Felipe Moura

    2017-01-01

    Belo Horizonte is the sixth most populous city in Brazil, has the third largest fleet of vehicles and it is close to large mineralogical reserves, such the Quadrilátero Ferrífero. These factors, coupled with the industrial growth and civil construction, raise questions about society regarding ambient air quality. A historically problematic contaminant is the particulate matter (PM), a mixture of solid and liquid particles in suspension that generate environmental damage and human health. These particles can cause from a simple infection to death, being their dimension a fundamental factor to evaluate the impact caused. In this context, this research investigated the air quality due to PM10 (particles less than 10 microns) in a high traffic flow of Minas Gerais capital, Presidente Antônio Carlos Avenue. This avenue is one of the main accesses to the region of Pampulha, an area of great tourist and sporting relevance of the city and has undergone works of duplication and implementation of exclusive lanes for public transport buses due to the realization of the 2014 World Cup. Involved monitoring in the avenue in the year 2014 in order to collect the PM10 present in the ambient air. The characterization of PM10 occurred with the use of the X-ray diffraction technique, one of the main tools of mineralogical characterization, due to its simplicity, speed and reliability of the obtained results. The minerals detected by the analysis were evaluated for their possible origin, generating information for the evaluation of PM10 emitting sources that are fundamental for the management of air quality in the city. (author)

  2. Concentration of metals adjacent to Tiete river border avenues; Concentracao de metais em solos adjacentes a Avenida Marginal do Rio Tiete, Sao Paulo

    Silva, Natalia C. e; Figueiredo, Ana M.G.; Ribeiro, Andreza P.; Nammoura Neto, Georges M.; Camargo, Sonia P.; Ticianelli, Regina B., E-mail: anamaria@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2009-07-01

    This work analysed different 5 cm depth fragments soils, with distinct characteristic s, collected at 8 points of the Tiete river marginal avenue at the Sao Paulo metropolitan region. The technique used for the analysis was the instrumental neutron activation analysis (INAA). Together with samples, metal concentration were measured in three reference materials BEN (IWG-GIT), GS-N (IWG-GIT) and Soil-7 (IAEA) for quality control of the results. These metals were analysed: arsenic (As), barium (Ba), chromium (Cr), cobalt (Co), antimony (Sb) e zinc (Zn); the obtained concentrations were compared with intervention limit values stipulated by the Companhia de Tecnologia de Saneamento Ambiental (CETESB). Those values indicate the soil quality for different use

  3. New avenues for framing research

    de Vreese, C.H.

    2012-01-01

    In this article, the author reviews the studies in this special issue of the American Behavioral Scientist. It is a strong collection of articles reporting findings from an integrated project that looks at frame building, frames, and effects of frames. The project is part of an exciting large-scale

  4. Results of the radiological survey at the Firemen's Memorial Park and Fire Hall No. 2, Garibaldi Avenue and Kennedy Drive, Lodi, New Jersey (LJ066)

    Foley, R.D.; Floyd, L.M.; Crutcher, J.W.

    1989-08-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally 232 Th, derived from the MCW site. The survey typically includes direct measurement of the gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, the Firemen's Memorial Park and Fire Hall number sign 2, Garibaldi Avenue and Kennedy Drive, Lodi, New Jersey (LJ066) was conducted during 1987. Results of the survey demonstrated radionuclide concentrations in excess of the DOE Formerly Utilized Sites Remedial Action Program criteria. The radionuclide distributions are typical of the type of material originating from the MCW site. 4 refs., 10 figs., 3 tabs

  5. Are the Insomnia Severity Index and Pittsburgh Sleep Quality Index valid outcome measures for Cognitive Behavioral Therapy for Insomnia? Inquiry from the perspective of response shifts and longitudinal measurement invariance in their Chinese versions.

    Chen, Po-Yi; Jan, Ya-Wen; Yang, Chien-Ming

    2017-07-01

    The purpose of this study was to examine whether the Insomnia Severity Index (ISI) and Pittsburgh Sleep Quality Index (PSQI) are valid outcome measures for Cognitive Behavioral Therapy for Insomnia (CBT-I). Specifically, we tested whether the factorial parameters of the ISI and the PSQI could remain invariant against CBT-I, which is a prerequisite to using their change scores as an unbiased measure of the treatment outcome of CBT-I. A clinical data set including scores on the Chinese versions of the ISI and the PSQI obtained from 114 insomnia patients prior to and after a 6-week CBT-I program in Taiwan was analyzed. A series of measurement invariance (MI) tests were conducted to compare the factorial parameters of the ISI and the PSQI before and after the CBT-I treatment program. Most factorial parameters of the ISI remained invariant after CBT-I. However, the factorial model of the PSQI changed after CBT-I treatment. An extra loading with three residual correlations was added into the factorial model after treatment. The partial strong invariance of the ISI supports that it is a valid outcome measure for CBT-I. In contrast, various changes in the factor model of the PSQI indicate that it may not be an appropriate outcome measure for CBT-I. Some possible causes for the changes of the constructs of the PSQI following CBT-I are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Materials Research Center, University of Pittsburgh

    1994-04-29

    enhanced extraction of phenobarbital. In the standard procedure for this often prescribed drug , an extraction with an organic solvent is used during...amount of drug with a volume of organic solvent that is one l 284 3 quarter of the volume of serum. The significance of this is in the minimization of...bonding subunit (acylaminopyridine/carboxylic acid pair) that will self-assemble into I alternating cocrystals in which the packing in the solid is

  7. Pittsburgh-Tuskegee Prostate Training Program

    2015-07-01

    University Fourth Joint Annual Research Symposium (JARS), February 27-28, 2014, Kellogg Hotel & Conference Center, Tuskegee, AL (**1st Place Poster...University Fourth Joint Annual Research Symposium (JARS), March 14-15, 2013, Kellogg Hotel & Conference Center, Tuskegee, AL Datiri, Yeipyeng...15, 2013, Kellogg Hotel & Conference Center, Tuskegee, AL Davis, Myles (2013) Cell Cycle G2/M Arrest by Inhibition of Protein Kinase D

  8. Trace element studies at University of Pittsburgh

    Cohen, B.L.; Chan, K.C.; Shabason, L.; Wedberg, G.; Rudolph, H.

    1974-01-01

    Seven areas of research are discussed. A method was developed for analyzing samples for their major constituent elements by irradiating with protons and detecting prompt gamma rays, mostly produced in (p,p'γ) reactions. Among other applications, the method was used to analyze air particulates for C, N, O, Al, Si, S, Co, and Fe. Trace element analysis by proton or alpha particle induced x-ray fluorescence was used on thin samples in a study of the variations of Pb, Br, Fe, and Zn in air particulates as a function of time. Among other applications this method was also used in studying trace elements in rainwater. An x-ray fluorescence method that is effective in the analysis of thick samples was developed. A method based on measuring energies of elastically scattered protons was developed for the analysis of light elements. The use of proton and neutron activation analyses, as well as methods for studying depth profiles for hydrogen and helium in materials are discussed

  9. Defending the Pittsburgh Waterways Against Catastrophic Disruption

    2012-06-01

    by the Hannibal L/D. Along the Allegheny River our AOI is bounded by the Allegheny L/D 5. Along the Monongahela River our AOI is bounded by the...22  Figure 9.  Dams segment the river into pools, which are numbered. Locks enable transit between pools. The Hannibal L/D and the Pike Island...AOI, listed in the table to the right. Along the Ohio River our AOI is bounded by the Hannibal L/D. Along the Allegheny River our AOI is bounded by

  10. Ninth annual international Pittsburgh coal conference - proceedings

    Anon.

    1992-01-01

    Over 200 papers are presented under the following headings: coal preparation; Clean Coal Technology Program status; pre- and post-utilization processing; advanced conversion technologies; integrated gasification combined cycle; indirect liquefaction; advanced liquefaction process development; conversion processes; coal - from a user's perspective; issues associated with coal use in heat engines; fundamentals of combustion; advanced combustion systems; low quality fuel applications/fluidised beds; combustion systems; ash and sludge disposal/utilization; developing SO 2 /NO x control technologies; technical overview of air toxics; scientific, economic and policy perspectives on global climate change; Clean Air Act compliance strategies; environmental policy/technology; spontaneous combustion; and special topics

  11. Three-dimensional visualization maps of suspended-sediment concentrations during placement of dredged material in 21st Avenue West Channel Embayment, Duluth-Superior Harbor, Duluth, Minnesota, 2015

    Groten, Joel T.; Ellison, Christopher A.; Mahoney, Mollie H.

    2016-06-30

    Excess sediment in rivers and estuaries poses serious environmental and economic challenges. The U.S. Army Corps of Engineers (USACE) routinely dredges sediment in Federal navigation channels to maintain commercial shipping operations. The USACE initiated a 3-year pilot project in 2013 to use navigation channel dredged material to aid in restoration of shoreline habitat in the 21st Avenue West Channel Embayment of the Duluth-Superior Harbor. Placing dredged material in the 21st Avenue West Channel Embayment supports the restoration of shallow bay aquatic habitat aiding in the delisting of the St. Louis River Estuary Area of Concern.The U.S. Geological Survey, in cooperation with the USACE, collected turbidity and suspended-sediment concentrations (SSCs) in 2014 and 2015 to measure the horizontal and vertical distribution of SSCs during placement operations of dredged materials. These data were collected to help the USACE evaluate the use of several best management practices, including various dredge material placement techniques and a silt curtain, to mitigate the dispersion of suspended sediment.Three-dimensional visualization maps are a valuable tool for assessing the spatial displacement of SSCs. Data collection was designed to coincide with four dredged placement configurations that included periods with and without a silt curtain as well as before and after placement of dredged materials. Approximately 230 SSC samples and corresponding turbidity values collected in 2014 and 2015 were used to develop a simple linear regression model between SSC and turbidity. Using the simple linear regression model, SSCs were estimated for approximately 3,000 turbidity values at approximately 100 sampling sites in the 21st Avenue West Channel Embayment of the Duluth-Superior Harbor. The estimated SSCs served as input for development of 12 three-dimensional visualization maps.

  12. Cedar Avenue driver assist system evaluation report.

    2011-12-01

    This paper summarizes an evaluation of the Driver Assist System (DAS) used by the Minnesota Valley Transit Authority (MTVA) for bus shoulder operations. The DAS is a GPS-based technology suite that provides lane-position feedback to the driver via a ...

  13. Buncrana Community Hospital, Maginn Avenue, Buncrana, Donegal.

    Owens, Lisa A

    2010-03-01

    OBJECTIVE A prospective study of the impact of obesity on pregnancy outcome in glucose-tolerant women. RESEARCH DESIGN AND METHODS The Irish Atlantic Diabetes in Pregnancy network advocates universal screening for gestational diabetes. Women with normoglycemia and a recorded booking BMI were included. Maternal and infant outcomes correlated with booking BMI are reported. RESULTS A total of 2,329 women fulfilled the criteria. Caesarean deliveries increased in overweight (OW) (odds ratio 1.57 [95% CI 1.24-1.98]) and obese (OB) (2.65 [2.03-3.46]) women. Hypertensive disorders increased in OW (2.30 [1.55-3.40]) and OB (3.29 [2.14-5.05]) women. Reported miscarriages increased in OB (1.4 [1.11-1.77]) women. Mean birth weight was 3.46 kg in normal BMI (NBMI), 3.54 kg in OW, and 3.62 kg in OB (P < 0.01) mothers. Macrosomia occurred in 15.5, 21.4, and 27.8% of babies of NBMI, OW, and OB mothers, respectively (P < 0.01). Shoulder dystocia occur in 4% (>4 kg) compared with 0.2% (<4 kg) babies (P < 0.01). Congenital malformation risk increased for OB (2.47 [1.09-5.60]) women. CONCLUSIONS OW and OB glucose-tolerant women have greater adverse pregnancy outcomes.

  14. Alphabet Avenue: Wordplay in the Fast Lane.

    Morice, Dave

    This collection of palindromes, pangrams, acrostics, word squares and word ladders, visual and numerical puzzles, silly names, and much more is designed to delight, surprise, and challenge both the novice and the expert player of word games. It uses the metaphor of a busy, cosmopolitan city to showcase three facets of words: forms of letters,…

  15. Avenues of Influence: Cross-Cultural Implications

    2014-04-01

    focused on comparisons between individualistic and collectivistic cultures . Furthermore, given the differential emphasis toward group factors in...either individualistic or collectivistic cultures , social influence tactics involving group social elements may be a good starting point for exploring...in Two Cultures : The Differential Influence of Social Proof and Commitment/Consistency on collectivists and Individualists . Personality and Social

  16. National Constitutional Avenues for Further EU Integration

    Besselink, L.F.M.; Claes, M.; Imamovic, Š.; Reestman, J.H.

    2014-01-01

    This study investigates national constitutional limits to further EU integration and explores ways to overcome them. It includes an in-depth examination of the constitutional systems of 12 Member States (Croatia, the Czech Republic, Estonia, Finland, France, Germany, Hungary, Ireland, Italy, the

  17. New Avenues for Nanoparticle-Related Therapies

    Zhao, Michael; Liu, Mingyao

    2018-05-01

    Development of nanoparticle-based drug delivery systems has been attempted for the treatment of cancer over the past decade. The enhanced permeability and retention (EPR) effect is the major mechanism to passively deliver nanodrugs to tumor tissue. However, a recent systematic review demonstrated limited success of these studies, with the clearance of nanoparticles by the mononuclear phagocytic system (MPS) being a major hurdle. Herein, we propose that nanotechnologists should reconsider their research focuses, aiming for therapeutic targets other than cancer. Treatments for diseases that do not (or less) rely on EPR should be considered, such as active targeting or MPS evasion systems. For example, systemic delivery of drugs through intravenous injection can be used to treat sepsis, multi-organ failure, metabolic disorders, blood diseases, immune and autoimmune diseases, etc. Local delivery of nanodrugs to organs such as the lung, rectum, or bladder may enhance the local drug concentration with less clearance via MPS. In transplant settings, ex vivo organ perfusion provides a new route to repair injury of isolated organs in the absence of MPS. Based on a similar concept, chemotherapy with in vivo lung perfusion techniques and other isolated organ perfusion provides opportunities for cancer therapy.

  18. New avenues in hypoxic cell sensitization

    Huilgol, N.G.; Chatterjee, N.A.; Singh, B.B.

    1995-01-01

    Hypoxic cells in tumors represent a population of cells that are resistant to radiotherapy. Bio-reductive agents like RSU 1069, RBU 6145 and EOg and vasoactive drugs in conjunction with hypoxic cell sensitizers are being evaluated as hypoxic cell cytotoxins. Chlorpromazine a membrane active drug and AK-2123- a nitrotriazole with a potential to deplete intracellular thiols induced vasoconstriction and sensitize hypoxic cells have stretched the boundaries of innovation. A preliminary experience with these drugs is discussed. 8 refs., 2 tabs., 2 figs

  19. MEDICAL TOURISM IN INDIA: A NEW AVENUE

    Badwe, Anand N.; Giri, Purushottam A; Latti, Ramchandra G.

    2012-01-01

    Medical tourism is attracting attention of travelers from all over the globe. It combines a travel at ease and availing medical health care facility at low cost as per traveler’s own choice. World class medical health care is available in some of the Asian countries, such as India, Philippines and Singapore etc. Medical tourism has become one of the major industries in recent times. Medical Tourism India (Health Tourism India) is a developing concept whereby people from world over visit Ind...

  20. Modularization as an avenue to economic competitiveness

    Cottrell, J H [Avondale Industries, Inc., Rumson, NJ (United States)

    1990-07-01

    There are many features of the emerging next generation of nuclear power which impact the competitiveness of the facilities. We will focus on the equipment fabrication and erection phase of the work. Utility plants, like other complex facilities, require comprehensive program management skills. While any project is sensitive to cost, schedule and quality control, nuclear plants have strict and regulated requirements associated with quality control, and its associated materials source and record keeping. The industry has developed an increasing interest in the adaptation of prefabrication, or modularization, to the design, engineering and construction of power plants. Avondale Industries has been actively involved for the past several years with the DOE/EPRI sponsored Westinghouse design for an advanced passive 600 MWe PWR nuclear power plant (the AP-600). The Westinghouse team is currently working on the detailed design and NRC licensing/design certification phase. This program is a part of the current industry advanced light water (ALWR) efforts aimed at re-establishing the nuclear power option to meet U.S. electric generation needs in the 1990s and beyond. The Westinghouse program has the objective of developing the conceptual design of a greatly simplified 600 MWe pressurized water reactor plant with major improvements in safety, licensing certainty, life cycle cost, and construction schedule. One of the major tasks of the program is the development of an optimized plant arrangement and construction approach using modular construction to assist in achieving a short construction schedule and cost-effective plant configuration. Although the finite effect of modularization has yet to be tested in the dynamics of the erection of a commercial nuclear power plant, we feel that there is sufficient evidence from experience in other major manufacturing areas to warrant its application to future construction programs. In order to focus on the potential for modular construction, we will first review its evolution from marine construction into the industrial arena. Shipyards are ideally suited for diversification into modular construction of industrial, commercial and utility facilities. Our large inventory of heavy materials handling equipment contributes significantly to the efficiency of the fabrication operation. This coupled with automated materials preparation facilities, allow major projects to be constructed in a manufacturing environment. Major shipyards have the sophisticated infrastructure, and the flexibility of its application, needed to support the manufacture of single modules or large complex systems with comparable efficiency. We will give you a brief history on the evolution of modular construction as applied to major construction projects. While many of the illustrations will naturally be associated with the activities of Avondale Industries, they are also representative of other major manufacturing organizations. Prefabrication, or modularization, has been practiced for many decades by the marine construction industry. The WWII Liberty Ships are a prime example. Non-marine modules also have a long history. The latter were primarily prompted by remote sites, with attended shortage of skilled labor or hostile environmental conditions, and historically associated with the oil or petrochemical industry. Avondale Industries employs a comprehensive system of modular construction to build its projects. In general terms, this means that large projects are subdivided into efficiently managed sizes. These subdivisions, or modules, are designed, fabricated and managed as 'zones.' Our approach is not merely the structural design and construction of discrete modules. It is a comprehensive construction management system that begins in the planning, design and engineering phases and carries through into material procurement, zone outfitting, site erection, start-up, operation and maintenance. A key element of the planning and design functions is the emphasis on constructability. We employ production lanes, or areas, whe re the various fabrication activities are performed on the zones. Unlike traditional field construction, we take the work to the workers, not the workers to the work. A typical ship might have 150-200 zones. The application of the marine building procedures to non-ship projects was a logical evolution. For example, a major ship requires upwards of 300,000 individual items of material and equipment t be in the right place, at the right time and of the right specification and design in order to expeditiously complete a project. A modem container ship will require about 10,000 pipe spools, 350,000 feet of electrical cable, and 2200 drawings. The fundamental steps in the fabrication process are essentially the same for marine vessels and industrial facilities. Instead of transporting the outfitted zones several hundred yards, or up to a few miles, for incorporation into a ship, the zones may be shipped thousands of miles to the permanent pant or facility site. The size and dimension of the transportable zones is a function of the plant site location. Sites accessible by navigable water systems can incorporate large outfitted zones. The following are a series of slides which illustrate some of the studies and projects utilizing modular construction. (author)

  1. Modularization as an avenue to economic competitiveness

    Cottrell, J.H.

    1990-01-01

    There are many features of the emerging next generation of nuclear power which impact the competitiveness of the facilities. We will focus on the equipment fabrication and erection phase of the work. Utility plants, like other complex facilities, require comprehensive program management skills. While any project is sensitive to cost, schedule and quality control, nuclear plants have strict and regulated requirements associated with quality control, and its associated materials source and record keeping. The industry has developed an increasing interest in the adaptation of prefabrication, or modularization, to the design, engineering and construction of power plants. Avondale Industries has been actively involved for the past several years with the DOE/EPRI sponsored Westinghouse design for an advanced passive 600 MWe PWR nuclear power plant (the AP-600). The Westinghouse team is currently working on the detailed design and NRC licensing/design certification phase. This program is a part of the current industry advanced light water (ALWR) efforts aimed at re-establishing the nuclear power option to meet U.S. electric generation needs in the 1990s and beyond. The Westinghouse program has the objective of developing the conceptual design of a greatly simplified 600 MWe pressurized water reactor plant with major improvements in safety, licensing certainty, life cycle cost, and construction schedule. One of the major tasks of the program is the development of an optimized plant arrangement and construction approach using modular construction to assist in achieving a short construction schedule and cost-effective plant configuration. Although the finite effect of modularization has yet to be tested in the dynamics of the erection of a commercial nuclear power plant, we feel that there is sufficient evidence from experience in other major manufacturing areas to warrant its application to future construction programs. In order to focus on the potential for modular construction, we will first review its evolution from marine construction into the industrial arena. Shipyards are ideally suited for diversification into modular construction of industrial, commercial and utility facilities. Our large inventory of heavy materials handling equipment contributes significantly to the efficiency of the fabrication operation. This coupled with automated materials preparation facilities, allow major projects to be constructed in a manufacturing environment. Major shipyards have the sophisticated infrastructure, and the flexibility of its application, needed to support the manufacture of single modules or large complex systems with comparable efficiency. We will give you a brief history on the evolution of modular construction as applied to major construction projects. While many of the illustrations will naturally be associated with the activities of Avondale Industries, they are also representative of other major manufacturing organizations. Prefabrication, or modularization, has been practiced for many decades by the marine construction industry. The WWII Liberty Ships are a prime example. Non-marine modules also have a long history. The latter were primarily prompted by remote sites, with attended shortage of skilled labor or hostile environmental conditions, and historically associated with the oil or petrochemical industry. Avondale Industries employs a comprehensive system of modular construction to build its projects. In general terms, this means that large projects are subdivided into efficiently managed sizes. These subdivisions, or modules, are designed, fabricated and managed as 'zones.' Our approach is not merely the structural design and construction of discrete modules. It is a comprehensive construction management system that begins in the planning, design and engineering phases and carries through into material procurement, zone outfitting, site erection, start-up, operation and maintenance. A key element of the planning and design functions is the emphasis on constructability. We employ production lanes, or areas, whe re the various fabrication activities are performed on the zones. Unlike traditional field construction, we take the work to the workers, not the workers to the work. A typical ship might have 150-200 zones. The application of the marine building procedures to non-ship projects was a logical evolution. For example, a major ship requires upwards of 300,000 individual items of material and equipment t be in the right place, at the right time and of the right specification and design in order to expeditiously complete a project. A modem container ship will require about 10,000 pipe spools, 350,000 feet of electrical cable, and 2200 drawings. The fundamental steps in the fabrication process are essentially the same for marine vessels and industrial facilities. Instead of transporting the outfitted zones several hundred yards, or up to a few miles, for incorporation into a ship, the zones may be shipped thousands of miles to the permanent pant or facility site. The size and dimension of the transportable zones is a function of the plant site location. Sites accessible by navigable water systems can incorporate large outfitted zones. The following are a series of slides which illustrate some of the studies and projects utilizing modular construction. (author)

  2. China's "Great Leap" toward Madison Avenue.

    Anderson, Michael H.

    1981-01-01

    Examines the expanding use of advertising in China. Discusses the impact of transnational corporations in communication and other areas on the development of China, and the implications that the introduction of advertising has for China's role as one of the models for developing countries. (JMF)

  3. Erythropoietin in cardiovascular diseases : exploring new avenues

    Van der Meer, Peter; Veldhuisen, Dirk J. N.; Januzzi, James L.

    Cardiovascular disease is an important burden in the Western world, with a prevalence that is increasing exponentially. Indeed, the lifetime risk of coronary artery disease at 40 years of age is I in 2 for men and I in 3 for women, and it is estimated that one-third of the population worldwide will

  4. Pharmaceutical technology management--profitable business avenue.

    Puthli, Shivanand P

    2010-01-01

    Growing research expenditure, regulatory framework and generic erosion have forced pharmaceutical companies globally to resort to pharmaceutical technology management (PTM). Indeed, the pharmaceutical industry has witnessed the impact of innovative drug delivery and device technologies and their influence on business. PTM has given a new business insight with greater profits and enhancement of product franchise. Promising breakthrough technologies have not been able to reach a commercial platform largely owing to lack of capital at the preliminary stages of the product development program. Intellectual property plays a considerable role in protecting innovative technologies. Joint ventures and strategic alliances also become important for commercializing a new technology. The synergy of PTM with options of in-licensing is expected to infuse newer opportunities to the pharmaceutical business.

  5. Solar transit stops on Central Avenue.

    2011-02-01

    This initiative sought to demonstrate existing commercially available transportation technologies for transit customer amenities that could significantly enhance transit experience and attract more riders therefore making the Capital District Tra...

  6. Jim Shaw's The Hidden World as a Book of Poetry

    Sørensen, Bent

    documents, ’found’ in pulp publications, in thrift stores, on billboards, and on the Internet. These documents are mostly word-image hybrids, and their original functions may have been as commercials or advertisements, religious propaganda, doomsday prophecies, or other forms of naïve “didactic art...... of pulp art (often cited as his source of inspiration for his ‘real’ art), but by utilizing the book medium for its presentation, and further visually imitating the format of holy scripture, he has also opened up for his work to be read as one would a collection of sacred texts, say, a Bible – or even...

  7. Exercise rehabilitation in pulmonary patients: a review | Shaw ...

    Although aerobic exercise (specifically lower-body) continues to be the most popular mode of exercise for pulmonary rehabilitation, many lung patients report disabling symptoms for daily activities involving the upper extremities. The principal difference between aerobic training and resistance training (RT) modes of ...

  8. Shaw Air Force Base Infrastructure Project Environmental Assessment

    2008-09-01

    are the applied to the following factors depending on the corresponding years. Year 2009: VOCE = .016 * Trips NOXE = .015 * Trips PM10E...0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOXE = .013 * Trips PM10E = .0022 * Trips COE = .262 * Trips To...convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 Nox (tons/yr) = NOxE * DPYII/2000 PM10(tons/yr) = PM10E

  9. About some trematodes parasites of Haemulon sciurus (Shaw, 1803

    A. Kohn

    1982-06-01

    Full Text Available From September, 1980 to August, 1981 forty specimens of Haemulon sciurus from "Praia da Ribeira, Ilha do Governador", Rio de Janeiro State, were examined for parasites. In this paper, parcial results concerning only the collected trematodes are reported: Diplomonorchis leiostomi Hopkins, 1941 (first record in Brazil and in a new host; Lasiotocus beauforti (Hopkins, 1941 Thomas, 1959 (new host record; Genolopa ampullacea Linton, 1910; Parahemiurus merus (Linton, 1910 Yamaguti, 1938 (new host record: Aponurus pyriformis (Linton, 1910 Overstreet, 1973 and Diplangus paxillus Linton, 1910. Figures, measurements and comments of each species are given.De setembro, 1980 a agosto, 1981 foram examinados 40 exemplares de Haemulon sciurus, provenientes da Praia da Ribeira, Ilha do Governador, Estado do Rio de Janeiro. Neste trabalho são apresentados os resultados parciais, correspondentes aos trematodeos, grupo que apresentou maior ocorrência de parasitismo. As especies estudadas foram: Diplomonorchis leiostomi Hopkins, 1941 (primeira ocorrencia no Brasil e em novo hospedeiro; Lasiotocus beauforti (Hopkins, 1941 Thomas, 1959 (em novo hospedeiro; Genolopa ampullacea Linton, 1910; Parahemiurus merus (Linton, 1910 Yamaguti, 1938 (em um novo hospedeiro; Aponurus pyriformis (Linton, 1910 Overstreet, 1973 e Diplangus paxillus Linton, 1910. São apresentadas figuras, medidas e comentários.

  10. An Experimental System for Research on Dynamic Skills Training.

    1981-09-01

    Bogey to be intercepted. The student enters B1 . The system then displays a recommended intercept heading, say 270 degrees. The student must now send this...DRIVE LRDC OTTAWA, CANADA K1A 0K2 UNIVERSITY OF PITTSBURGH 3939 O’HARA STREET ERIC Facility-Acquisitions PITTSBURGH, PA 15213 4833 Rugby Avenue Bethesda

  11. Clinical impact of (11)C-Pittsburgh compound-B positron emission tomography carried out in addition to magnetic resonance imaging and single-photon emission computed tomography on the diagnosis of Alzheimer's disease in patients with dementia and mild cognitive impairment.

    Omachi, Yoshie; Ito, Kimiteru; Arima, Kunimasa; Matsuda, Hiroshi; Nakata, Yasuhiro; Sakata, Masuhiro; Sato, Noriko; Nakagome, Kazuyuki; Motohashi, Nobutaka

    2015-12-01

    The purpose of this study was to evaluate the clinical impact of addition of [(11)C]Pittsburgh compound-B positron emission tomography ((11)C-PiB PET) on routine clinical diagnosis of Alzheimer's disease (AD) dementia and mild cognitive impairment (MCI), and to assess diagnostic agreement between clinical criteria and research criteria of the National Institute on Aging-Alzheimer's Association. The diagnosis in 85 patients was made according to clinical criteria. Imaging examinations, including both magnetic resonance imaging and single-photon emission computed tomography/computed tomography to identify neuronal injury (NI), and (11)C-PiB PET to identify amyloid were performed, and all subjects were re-categorized according to the research criteria. Among 40 patients with probable AD dementia (ProAD), 37 were NI-positive, 29 were (11)C-PiB-positive, and 27 who were both NI- and (11C-PiB-positive were categorized as having 'ProAD dementia with a high level of evidence of the AD pathophysiological process'. Among 20 patients with possible AD dementia (PosAD), 17 were NI-positive, and six who were both NI- and (11)C-PiB-positive were categorized as having 'PosAD with evidence of the AD pathophysiological process'. Among 25 patients with MCI, 18 were NI-positive, 13 were (11)C-PiB-positive, and 10 who were both NI- and (11)C-PiB-positive were categorized as having 'MCI due to AD-high likelihood'. Diagnostic concordance between clinical criteria and research criteria may not be high in this study. (11)C-PiB PET may be of value in making the diagnosis of dementia and MCI in cases with high diagnostic uncertainty. © 2015 The Authors. Psychiatry and Clinical Neurosciences © 2015 Japanese Society of Psychiatry and Neurology.

  12. Planning Guide for Fish Passage at Pittsburgh District Dams

    2013-08-01

    attracted to a downstream flow at the entrance gate of the lift. 2) Immigrants pass around a moveable crowder that, when engaged, forces fish into the...might influence fish passage over a large number of sites. REFERENCES Bailey, M. M., J. J. Isely, and W. C. Bridges , Jr. 2004. Movement and

  13. Experimental particle physics at the University of Pittsburgh

    Cleland, W.E.; Engels, E. Jr.; Humanic, T.J.; Perera, U.; Shepard, P.F.; Thompson, J.A.

    1993-04-01

    During the past year on Task A, the HELIOS work drew to a close with first results from the electron-muon pair studies (no anomalous sources are seen, and the final results and uncertainties are being set). First data from CMD2 will allow improvement of some phi branching ratios, including some improved limits on forbidden decays. The engineering run for E865 is scheduled for June and July of 1993. The principal efforts of Task B, the Fermilab program, have been the completion of the analysis of the 1987--88 data with resulting publications, completion of the 1990--91 data run, and the beginning of the analysis of the 1990--91 data. In addition, the Task B group is taking a leadership role in developing a proposal to Fermilab for the upgrade of the CDF silicon vertex detector in preparation for the 1995 data run. Task C has recently submitted results of its fractionally charged particle searches, placing new upper limits on the abundance of naturally-occurring fractionally-charged particles in various materials. This group has recently been approved by the Brookhaven management for an exposure of their p-i-n diodes in a high intensity proton beam. This measurement, along with its subsequent analysis, will complete the program. Task D concerned itself with silicon drift chamber studies for the SSC. Task E was devoted to studies of electronics for the GEM Level 1 liquid Ar calorimeter trigger

  14. AFIRM-Wake Forest/University of Pittsburgh Consortium

    2012-07-01

    agner WR. Synthesis , ch aracterization, and cytocompatibility of elas tomeric, biodegradable poly(ester-urethane) ureas based on poly(caprolactone) and...construct in vitro for enhanced functional recovery followi ng implantation in vivo in a m urine model of volumetric muscle loss (VML) injury. Ti ssue...were harv ested at 12, 18, and 24 hours and RNA extraction was perform ed, followed by P CR microarray analysis. cDNA synthesis was performed with

  15. EnviroAtlas - Pittsburgh, PA - Impervious Proximity Gradient

    U.S. Environmental Protection Agency — In any given 1-square meter point in this EnviroAtlas dataset, the value shown gives the percentage of impervious surface within 1 square kilometer centered over the...

  16. EnviroAtlas - Pittsburgh, PA - Greenspace Proximity Gradient

    U.S. Environmental Protection Agency — In any given 1-square meter point in this EnviroAtlas dataset, the value shown gives the percentage of square meters of greenspace within 1/4 square kilometer...

  17. Experimental particle physics at the University of Pittsburgh

    Cleland, W.E.; Coon, D.D.; Engels, E. Jr.; Shepard, P.; Thompson, J.A.

    1989-12-01

    This report discusses the following topics: HELIOS/1 and HELIOS/2; direct photon production at the Tevatron; search for fractional charge particles in semiconductors; and SSC ionization calorimetry studies

  18. Experimental particle physics at the University of Pittsburgh

    Engels, E. Jr.; Perera, U.; Shepard, P.; Thompson, J.A.

    1991-06-01

    This report discusses research on the following topics: helios; K-decay and CP violation at INP; rare K-decays at BNL; direct photon production at the Tevatron; CDF; and fractional charge particles in semiconductors

  19. Pittsburgh Student Veterans' Experience with Social Media in Higher Education

    Marsilio, Kenneth

    2016-01-01

    This study sought to understand how student veteran's experienced using social media in the context of higher education. It also explored how they used it for peer bonding and how student veterans perceived the benefits of using social media. This was a qualitative research study that used a phenomenological approach to data collection and…

  20. Mine flooding and barrier pillar hydrology in the Pittsburgh basin

    Leavitt, B.R.

    1999-01-01

    Pennsylvania began requiring barrier pillars between mines as early as 1930. The Ashley formula, resulting from a early commission on the problem, requires 20 feet of coal plus a thickness of coal equal to four times the seam height plus an additional thickness of coal equal to one tenth of the overburden thickness, or the maximum potential hydraulic head. For a 6-foot thick coal seam under 400 feet of cover, the barrier would be 20+24+40=84 feet. The Ashley formula is intended to protect coal miners from a catastrophic failure of a barrier pillar which has a high head of water impounded behind it. The paper gives several examples of flooded and unflooded mines and the performance of their barrier pillars with respect to acid mine drainage. It is concluded that for all practical purposes, barrier pillars designed with the Ashley formula are able to hydrologically isolate mines from one another. This hydrologic isolation promotes the inundation of closed mines. Inundation effectively stops acid formation, thus, fully inundated mines do not represent a perpetual source of acid mine drainage. Infiltrating ground water improves the mine water chemistry resulting in a net alkaline discharge which has greatly lowered iron concentrations. The best locations for acid mine drainage treatment plants is at the lowest surface elevation above the mine with mine flooded to near that elevation

  1. EnviroAtlas - Pittsburgh, PA - Land Cover by Block Group

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of each block group that is classified as impervious, forest, and green space. Forest is combination of trees and...

  2. Alternative Fuels Data Center: Pittsburgh Livery Company Transports

    hybrid, propane, and natural gas vehicles to transport customers. For information about this project Biodiesel Aug. 26, 2017 Photo of a car Idaho Surges Ahead with Electric Vehicle Charging Aug. 4, 2017 Photo a transit bus America's Largest Home Runs on Biodiesel in North Carolina June 9, 2017 Photo of a bus

  3. EnviroAtlas - Pittsburgh, PA - Near Road Block Group Summary

    U.S. Environmental Protection Agency — This EnviroAtlas dataset addresses the tree buffer along heavily traveled roads. The roads are interstates, arterials, and collectors within the EnviroAtlas...

  4. EnviroAtlas - Pittsburgh, PA - Near Road Tree Buffer

    U.S. Environmental Protection Agency — This EnviroAtlas dataset addresses the tree buffer along heavily traveled roads. The roads are interstates, arterials, and collectors within the EnviroAtlas...

  5. 76 FR 31612 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    2011-06-01

    ... Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C... bank holding company. The factors that are considered in acting on the notices are set forth in...) 90 Hennepin Avenue, Minneapolis, Minnesota 55480-0291: 1. Marci Johnson Shaw, Fairfield, Montana; to...

  6. 441 Assessment of Revenue Generation Avenues in Ecotourism ...

    Nekky Umera

    University of Port Harcourt, P.M.B.5323 Port Harcourt, Nigeria. E-mail: henryijeomah@yahoo.com. Ayodele, I.A. - Department of Wildlife and Fisheries Management,. University ... adjourning tourist centres complain of aculturization of contra culture and ..... Development in selected conservation areas in Nigeria, Ph.D. Thesis.

  7. JIEM's third year: Present status and future avenues

    Mihaela Enache

    2011-07-01

    Full Text Available This editorial builds upon the guidelines developed by the Journal of Industrial Engineering and Management (JIEM since its inception (Sallan et al., 2010; Simo et al., 2009; Fernandez et al., 2008 and reflects some relevant information about the evolution of JIEM during 2010, together with novel features that have been implemented so far or which are planned to be realized.

  8. Electronic Networking as an Avenue of Enhanced Professional Interchange.

    Ratcliff, James L.

    Electronic networking is communication between two or more people that involves one or more telecommunications media. There is electronic networking software available for most computers, including IBM, Apple, and Radio Shack personal computers. Depending upon the sophistication of the hardware and software used, individuals and groups can…

  9. industrial hand injuries as seen at avenue hospital, nairobi

    The first 4 hours of the shift accounted for 39 (52%) of the injuries. ... the body in traumatic occupational injuries (1). Work-. Related Hand Injuries (WRHI) result in functional impairment .... textile industries accounting for 16.8%. Crushing was ...

  10. CLIC/ILC Researchers Explore New Avenues for Collaboration

    Katarina Anthony

    2010-01-01

    Researchers from CLIC and ILC met for their first common International Workshop on Linear Colliders, which was held in Geneva from 18 to 22 October. Although the talks were mostly scientific and technical, the political message behind them was a breakthrough, as the workshop showed the progress made in unifying the two communities.   The International Workshop on Linear Colliders (IWLC), which was organised by the European Committee for Future Accelerators, hosted by CERN, and held at CERN and the International Conference Centre in Geneva, attracted a large audience of about 500 experts. Although there have been other joint conferences between the CLIC and ILC communities before, they have all been focused on specific technical and/or managerial issues. The IWLC was part of an ongoing effort by CLIC and ILC to provide an environment in which researchers can exchange ideas, inform their peers about their most recent achievements and work together on common issues. Given the possible technical ov...

  11. Student Organizations as Avenues for Leader Learning and Development.

    Sessa, Valerie I; Alonso, Nicole; Farago, Pamela; Schettino, Gaynell; Tacchi, Kelcie; Bragger, Jennifer D

    2017-09-01

    This chapter describes theory and research demonstrating that the experiences students have within student organizations, and the people with whom they interact within those organizations, are powerful triggers for leader learning and development. © 2017 Wiley Periodicals, Inc., A Wiley Company.

  12. Avenue T: Using Film as "Entree" in Teaching about Transgender

    Walters, Andrew S.; Rehma, Kae

    2013-01-01

    Educators from a variety of disciplines include the concept of transgender and multiple gender identities in course curricula. The "T" (denoting the specific inclusion of transgender) in the popular acronym LGBT (lesbian, gay, bisexual, transgender) often is given less pedagogical attention than is sexual orientation, and the transgender…

  13. Avenues of Influence Cross-Cultural Implications (Briefing Charts)

    2012-11-01

    cultural , Social Influence, Communication modality, Emotional contagion, Individualistic , Collectivistic , Group orientation, Behavioral influences 16...appeals to take additional training – Culture groups: Individualistic and Collectivistic – Six persuasive appeals will be used in the stimuli: rational...between media type and emotional contagion Does culture influence the impact of social proof? H4: Collectivistic cultures will engage in

  14. Therapeutic avenues for hereditary forms of retinal blindness

    CHITRA KANNABIRAN

    for Ocular Regeneration, and 3Prof Brien Holden Eye Research Centre, L. V. Prasad Eye Institute, Kallam Anji Reddy .... in the mid-peripheral field as measured by the Humphrey ..... clinical translation of this technology in the near future.

  15. AVENUES FOR THE DEVELOPMENT OF MUSICAL ABILITIES IN ...

    Mitch

    in Nigeria when he traced it to 1843 with the establishment of schools by Christian missions like ... Adegbite (2001) observes that in most private elementary and primary schools, music instructions ... ROMs, internet facilities and other electronic media. ... The Social Psychology of Music; USA: IOWA State University. Press.

  16. Response to 'Modularization as an avenue to economic competitiveness'

    Keene, W.P.

    1990-01-01

    Full text: Mr. Cottrell has done an excellent job in showing us how shipyards can play a vital role in the modular construction of large scale electromechanical processing plants. Land based nuclear power plants fit well into United States shipyard capabilities. Some American shipyards have always been innovative leaders in construction techniques and imaginative products. Avondale's recent association with the AP-600 project is no exception and I am grateful to have been asked to respond to this idea of shipyard participation in construction of advanced nuclear land based power plants. The American shipbuilding industry has witnessed a generally declining market over the past forty years; but in the face of that decline, a few very large and healthy shipyards have emerged. My company, Litton Industries' Ingalls Shipbuilding Division is among them. Indeed, the construction of nuclear reactors and their associated marine propulsion plants has continued unabated for thirty-five years in our private shipyards. More than 180 such plants have been built. Our own yard has built twelve and, in addition, overhauled and refueled an equal number. This nuclear experience, combined with the modular experience covered by Mr. Cottrell, would be a cornerstone in the use of shipyards to accelerate nuclear power plant development. As Mr. Cottrell has ably shown, the ability of shipyards to plan, construct and trans-ship very large modules to remote sites has been repeatedly demonstrated. Ingalls recently completed just such a project - a complete naval gas turbine propulsion and electric plant for crew training was built in Mississippi and shipped in modular form up the Atlantic and down the St. Lawrence Seaway into the Great Lakes training center. It is clear that today's large private shipyards have capacity, capability and experiences far in excess of what is needed for today's ship construction and repair requirements. Today, quantities such as: 140,000 tons of steel 450 miles of pipe 2800 miles of electrical cable 125 tons of ventilation duct are annual throughputs of our four largest shipyards. These quantities represent approximately 70% of capacity of the four major shipyards. This capacity is available in private shipyards because of continuing capital investments. More than four billion dollars of such investment resides in today's major shipyard facilities. The AP-600 power plant and possibly other passively safe type designs have reduced bulk quantities significantly. If we assume that as much as 75% of this design can be constructed as shipyard modules, then clearly two or three units per year fall within any one shipyard's annual capacity. Even with new ship construction levels equal to those of the past several years, modularized units for land based nuclear power plants of the AP-600 size could be produced at an annual rate of perhaps ten per year. skills already in place. Nearly all shipbuilding contracts are large scale, multiple unit, multiyear endeavors requiring technical design, world wide materiel purchasing, detail planning and scheduling, quality and cost control skills and techniques. Moreover, as previously mentioned, the shipbuilding community taken in a generic sense has been exposed to nuclear construction and the inherent quality control record keeping required by the U.S. Navy, the NRC and other regulatory agencies. Safety of handling equipment, community acceptance of constructing nuclear products and shipyard worker attitude would not bring any cultural shock into the industry. Of course, as with most issues, we must focus on costs. As Mr. Cottrell's work on the AP-600 project has revealed, costs would be reduced in choosing a shipyard for selected modules. Modular production has reduced ship costs by millions of manhours and modern, complex naval ships are in many respects more complex than power generating plants. Standard designs should not only enhance modularization but speed up the licensing process. Parallel construction paths are available to a prime plant contractor using one or more shipya rds. Learning curves of 85% and better are standard in the shipyards of the United States on multiple units. For those not familiar with learning curve calculations, this means that unit ten produced in a modem shipyard would cost about 85% of unit one. Although Ingalls has not sought out this market in the recent past, it will bear watching as the future unfolds a world where the gross consumption of fossil fuels (at least to produce electrical energy) must soon be curtailed. Indeed, it is becoming shameful that the United States with our demonstrated technological capabilities has not been the world leader in nuclear power generation. A national energy policy would be welcome to all Americans, and the shipbuilding industry has the ability and strength to contribute. Finally, I would like to congratulate Professor Michael Golay for arranging this First International Conference on this subject and look forward to participating. Perhaps in the future our shipyards may be called upon to examine solar and geothermal modular plants as well. (author)

  17. Vulnerability and Gambling Addiction: Psychosocial Benchmarks and Avenues for Intervention

    Suissa, Amnon Jacob

    2011-01-01

    Defined by researchers as "a silent epidemic" the gambling phenomenon is a social problem that has a negative impact on individuals, families and communities. Among these effects, there is exasperating evidence of comprised community networks, a deterioration of family and social ties, psychiatric co-morbidity, suicides and more recently,…

  18. Avenue for integrating geoethics into the working world.

    Boon, Jan

    2017-04-01

    GeoEthics is a young field and is taking shape through events such as the International Declaration on GeoEthics (2011) and conference sessions held since 2013 (http://www.geoethics.org/events). Many of these focused on the geoscience community and had an academic or educational focus. While interest in the subject is growing, the number of participants is still low as compared to that of other geoscience disciplines. The author has found it difficult to generate interest in the formal inclusion of geoethics and the related fields of social and environmental responsibility into university geoscience curricula. This paper proposes to link geoethics to the huge effort that has been under way over the past decade and a half in the extractive industries to develop industry-wide codes that facilitate and structure the introduction of social and environmental responsibility into company operations. All of these codes contain specific references to ethics. The paper builds on two well-developed codes: "e3 Plus - A Framework or Responsible Exploration" (Prospectors and Developers Association of Canada) and "Towards Sustainable Mining" (Mining Association of Canada) to propose an overall practical reference frame for geoethics that may facilitate the transfer of geoethicists' work into daily practice in the extractive industries.

  19. Elmhurst Nursing Home, Hampstead Avenue, Glasnevin, Dublin 9.

    Murphy, Melissa L

    2011-09-01

    Fractional anisotropy anomalies occurring in the white matter tracts in the brains of depressed patients may reflect microstructural changes underlying the pathophysiology of this disorder. We conducted a meta-analysis of fractional anisotropy abnormalities occurring in major depressive disorder using voxel-based diffusion tensor imaging studies. Using the Embase, PubMed and Google Scholar databases, 89 relevant data sets were identified, of which 7 (including 188 patients with major depressive disorder and 221 healthy controls) met our inclusion criteria. Authors were contacted to retrieve any additional data required. Coordinates were extracted from clusters of significant white matter fractional anisotropy differences between patients and controls. Relevant demographic, clinical and methodological variables were extracted from each study or obtained directly from authors. The meta-analysis was carried out using Signed Differential Mapping. Patients with depression showed decreased white matter fractional anisotropy values in the superior longitudinal fasciculus and increased fractional anisotropy values in the fronto-occipital fasciculus compared to controls. Using quartile and jackknife sensitivity analysis, we found that reduced fractional anisotropy in the left superior longitudinal fasciculus was very stable, with increases in the right fronto-occipital fasciculus driven by just one study. In conclusion, our meta-analysis revealed a significant reduction in fractional anisotropy values in the left superior longitudinal fasciculus, which may ultimately play an important role in the pathology of depression.

  20. REVIEW ARTICLE Therapeutic avenues for hereditary forms of ...

    chitra

    degenerations and dystrophies [Retinal Information Network, RetNet. .... out, and nutrients to diffuse in, while preventing the host immune system from attacking the ... amacrine cells, as well as the retinal nerve fiber layer, that are relatively ...

  1. DOE ZERH Case Study: Sunroc Builders, Bates Avenue, Lakeland, FL

    none,

    2015-09-01

    Case study of a DOE 2015 Housing Innovation Award winning affordable home in the hot-humid climate that got HERS 57 without PV, with 6.5” SIP walls and 8.25” SIP roof; uninsulated slab foundation; fresh air intake; SEER 16 ducted air source heat pump.

  2. Contingent Conversion Convertible Bond: New avenue to raise bank capital

    DI GIROLAMO FRANCESCA; CAMPOLONGO FRANCESCA; DE SPIEGELEER JAN; SCHOUTENS WIM

    2016-01-01

    This paper provides an in-depth analysis of the structuring and the pricing of an innovative financial market product. This instrument is called a contingent conversion convertible bond or "CoCoCo". This hybrid bond is itself a combination of two other hybrid instruments: a contingent convertible ("CoCo") and a convertible bond. This combination introduces more complexity in the structure but it also allows investors to profit from strong share price performances. This upside potential is add...

  3. Intracranial Pressure Monitoring—Review and Avenues for Development

    Maya Harary

    2018-02-01

    Full Text Available Intracranial pressure (ICP monitoring is a staple of neurocritical care. The most commonly used current methods of monitoring in the acute setting include fluid-based systems, implantable transducers and Doppler ultrasonography. It is well established that management of elevated ICP is critical for clinical outcomes. However, numerous studies show that current methods of ICP monitoring cannot reliably define the limit of the brain’s intrinsic compensatory capacity to manage increases in pressure, which would allow for proactive ICP management. Current work in the field hopes to address this gap by harnessing live-streaming ICP pressure-wave data and a multimodal integration with other physiologic measures. Additionally, there is continued development of non-invasive ICP monitoring methods for use in specific clinical scenarios.

  4. Identifying Avenues for Curriculum Development in Undergraduate Mathematics.

    Frid, Sandra; And Others

    The study reported in this paper represents the first stage of a five-year project aimed at improving the quality of teaching and learning in undergraduate mathematics courses for science and engineering students. Students were surveyed about their confidence in their mathematics background, their confidence with current mathematics topics, and…

  5. EFFECTIVE AVENUE OF ONLINE AND OFFLINE MARKETING IN CUSTOMER BEHAVIOR

    K. Umayal Parvathi; Dr. K. G. Selvan

    2018-01-01

    Over the past decade, businesses have either integrated or replaced their traditional marketing with digital marketing. For some, however, the question remains: Should offline marketing be abandoned, or does it still hold value in the age of the Internet? The divide between offline and online marketing has even led to companies hiring wholly separate teams to handle print, Web and social media projects. This leads to campaigns that are disconnected and may even directly compete with one anoth...

  6. Innovation avenues for coal derived power essential for the future

    Berkley, Mark; Cruz, Elizabet; Vatanakul, Maytinee; Hynes, Rory; Stickler, Alexander

    2010-09-15

    Current political climates are culminating in the conflict between economic development and environmental regulation -- Climate Change. Developed nations are driven by and dependent upon the cheap, abundant power of coal. Today, developing nations wish to duplicate this historical pathway, yet are subject to global scrutiny. The politico-economic conflict between nations may be alleviated by innovative technologies delivering power and improved environmental considerations. The long-term economic trend has been upward and thus targeting expanding and converting existing economies to utilize innovative technologies is fundamental to addressing the balance between socio-economic and environmental interests.

  7. New avenues in cobalt-60 production at Ontario Hydro

    Mylvaganam, C.K.; Ronchka, R.A.

    1990-01-01

    Ontario Hydro produces cobalt-60 in the control rods of twelve power reactors. These reactors have a typical flux of 2 x 10 14 neutrons/cm 2 /s, making them efficient producers of cobalt-60. Current annual production is 45 million curies. Since the primary function of these reactors is the production of electricity, their flexibility to meet the needs of commercial cobalt production by the control rod route is limited. Ontario Hydro is therefore developing innovative production techniques, making use of the CANDU reactor's unique ability to be fuelled on-power. These techniques will enable production to better respond to the market's requirements for quantity and specific activity. As it is supplementary to control rod production, annual supply could potentially reach 165 million curies. (author)

  8. Gorgias on Madison Avenue: Sophistry and the Rhetoric of Advertising.

    Matcuk, Matt

    Using sophistic theory and focusing on intersections in the practice and reception of sophistry and advertising, a study analyzed a contemporary advertising campaign. A number of extrinsic similarities between sophistic and advertising rhetoric exist: their commercial basis, their popular reception as dishonest speech, and the reception of both as…

  9. Ion-paired Drug Delivery: An Avenue for Bioavailability Improvement ...

    EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/sljbr.v3i2.71806 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

  10. JIEM's fourth year - Present status and future avenues

    Vicenc Fernandez

    2012-06-01

    Full Text Available This editorial reflects some relevant information about the evolution of JIEM during 2011, together with novel features that have been implemented so far or which are planned to be realized.

  11. Nonsteroidal anti-inflammatory drug gastropathy: new avenues for safety

    Roth SH

    2011-05-01

    Full Text Available Sanford H RothArizona Research and Education, Arthritis Laboratory, Arizona State University, Phoenix, AZ, USAAbstract: Chronic oral or systemic nonselective nonsteroidal anti-inflammatory drug (NSAID therapy, ubiquitously used by physicians to treat osteoarthritis-associated pain, is associated with a wide range of symptomatic adverse events, the most frequent and serious of which is gastropathy. Although cardiovascular and renal problems are a very real concern, they are significantly less frequent. These complications can be life-threatening in at-risk populations such as older adults, who are common users of long-term oral systemic NSAID therapy. Topical NSAID formulations deliver effective doses of analgesics directly to the affected joints, thereby limiting systemic exposure and potentially the risk of systemic adverse events, such as gastropathy and serious cardiovascular events. There are currently two topical NSAIDs approved by the US Food and Drug Administration for osteoarthritis-associated pain, as well as for the signs and symptoms of osteoarthritis. This review discusses the relative safety, and the gastrointestinal, cardiovascular, and renal risks of chronic oral or systemic NSAID therapy and topical NSAID formulations in patients with osteoarthritis.Keywords: NSAIDs, osteoarthritis, topical administration, synovial fluid, peptic ulcer, Helicobacter pylori

  12. Nonsteroidal anti-inflammatory drug gastropathy: new avenues for safety.

    Roth, Sanford H

    2011-01-01

    Chronic oral or systemic nonselective nonsteroidal anti-inflammatory drug (NSAID) therapy, ubiquitously used by physicians to treat osteoarthritis-associated pain, is associated with a wide range of symptomatic adverse events, the most frequent and serious of which is gastropathy. Although cardiovascular and renal problems are a very real concern, they are significantly less frequent. These complications can be life-threatening in at-risk populations such as older adults, who are common users of long-term oral systemic NSAID therapy. Topical NSAID formulations deliver effective doses of analgesics directly to the affected joints, thereby limiting systemic exposure and potentially the risk of systemic adverse events, such as gastropathy and serious cardiovascular events. There are currently two topical NSAIDs approved by the US Food and Drug Administration for osteoarthritis-associated pain, as well as for the signs and symptoms of osteoarthritis. This review discusses the relative safety, and the gastrointestinal, cardiovascular, and renal risks of chronic oral or systemic NSAID therapy and topical NSAID formulations in patients with osteoarthritis.

  13. Nonsteroidal anti-inflammatory drug gastropathy: new avenues for safety

    Roth, Sandford

    2011-01-01

    Sanford H RothArizona Research and Education, Arthritis Laboratory, Arizona State University, Phoenix, AZ, USAAbstract: Chronic oral or systemic nonselective nonsteroidal anti-inflammatory drug (NSAID) therapy, ubiquitously used by physicians to treat osteoarthritis-associated pain, is associated with a wide range of symptomatic adverse events, the most frequent and serious of which is gastropathy. Although cardiovascular and renal problems are a very real concern, they are significantly less...

  14. Big Data in Management Research : Exploring New Avenues

    C.I.S.G. Lee (Colin)

    2016-01-01

    markdownabstractDigital computers entered our homes, landed on our desktops, slipped into our pockets, and have seemingly become ubiquitous. At an ever faster pace, these devices have become highly interconnected and interoperable. Consequently, our archives, our work, our actions, and our

  15. Live-cell imaging: new avenues to investigate retinal regeneration

    Manuela Lahne

    2017-01-01

    Full Text Available Sensing and responding to our environment requires functional neurons that act in concert. Neuronal cell loss resulting from degenerative diseases cannot be replaced in humans, causing a functional impairment to integrate and/or respond to sensory cues. In contrast, zebrafish (Danio rerio possess an endogenous capacity to regenerate lost neurons. Here, we will focus on the processes that lead to neuronal regeneration in the zebrafish retina. Dying retinal neurons release a damage signal, tumor necrosis factor α, which induces the resident radial glia, the Müller glia, to reprogram and re-enter the cell cycle. The Müller glia divide asymmetrically to produce a Müller glia that exits the cell cycle and a neuronal progenitor cell. The arising neuronal progenitor cells undergo several rounds of cell divisions before they migrate to the site of damage to differentiate into the neuronal cell types that were lost. Molecular and immunohistochemical studies have predominantly provided insight into the mechanisms that regulate retinal regeneration. However, many processes during retinal regeneration are dynamic and require live-cell imaging to fully discern the underlying mechanisms. Recently, a multiphoton imaging approach of adult zebrafish retinal cultures was developed. We will discuss the use of live-cell imaging, the currently available tools and those that need to be developed to advance our knowledge on major open questions in the field of retinal regeneration.

  16. TOPOGRAPHY AND VISCERAL MORPHOLOGY OF THE Melopsittacus undulatus, SHAW 1805 TOPOGRAFIA E MORFOLOGIA DAS VÍSCERAS DO PERIQUITO-AUSTRALIANO (Melopsittacus undulatus, SHAW 1805

    Fabiana S. Matsumoto

    2009-12-01

    Full Text Available

    The aim of this research was to study the topography and morphology of Australian parakeet (Melopsittacus undulatus viscera. Ten Australian parakeet were used (5 males and 5 females. The animals were fixed in 10% formaldehyde solution, through perfusion in the musculature and visceral cavity. Macroscopically, the Australian parakeet viscera did not show expressive differences when compared to other domestic birds’ species. Microscopically, the main difference was the presence of mechanoreceptors (Corpuscles of Pacini in the tongue, found for the first time in this psittaciform  species.

    KEY WORDS: Melopsittacus undulatus, morphology, topography, viscera.

    Em virtude da escassez de dados referentes à morfologia e topografia das aves em geral, o presente estudo teve como objetivo descrever a topografia e morfologia das vísceras do periquito-australiano (Melopsittacus undulatus, para assim proporcionar um conhecimento mais amplo sobre características específicas dessa espécie. Para a descrição da morfologia e topografia das vísceras foram utilizados dez periquitos, sendo cinco machos e cinco fêmeas. Os animais foram fixados com solução de formaldeído 10%, através de perfusão na musculatura e cavidade visceral. Macroscopicamente, as vísceras do periquito não apresentaram muitas diferenças comparadas a outras espécies de aves domésticas. Microscopicamente, a principal diferença estava na presença de mecanorreceptores (corpúsculos de Pacini na língua, encontrados pela primeira vez nesta espécie de psitaciforme. 

    PALAVRAS-CHAVES: Melopsittacus undulatus, morfologia, topografia, vísceras.

  17. Low Response Rate and Other Factors Render Academic Health Science Library System Study Ungeneralizable. A Review of: Folb, B. L., Wessel, C. B., & Czechowski, L. J. (2011. Clinical and academic use of electronic and print books: The Health Sciences Library System e-book study at the University of Pittsburgh. Journal of the Medical Library Association, 99(3, 218-228. doi:10.3163/1536-5050.99.3.009

    Maria Melssen

    2012-06-01

    Full Text Available Objective – To determine the factors, barriersand facilitators, preference, and intended useof e-book compared to print book usage by allpatrons in a health science library system,which serves a university with health sciencedegree programs and a hospital system.Design – Two online surveys.Setting – University of Pittsburgh HealthSciences Library System, which includes theUniversity of Pittsburgh’s six schools of healthsciences (medicine, dental medicine, nursing,pharmacy, public health, and rehabilitationand the University of Pittsburgh MedicalCenter hospitals and programs.Subjects – All health sciences library systemusrers, including faculty, researchers, clinicians,residents, fellows, employees, and students.Methods – Two versions of the survey weredeployed in 2009 using Opinio. There were 46questions for the University of PittsburghMedical Center (UPMC survey and 47questions for the University of Pittsburgh (Pittsurvey. The surveys were pilot tested byHealth Sciences Library System (HSLSlibrarians and graduate students in a surveymethods class. The survey was edited based onthe feedback provided and receivedinstitutional review board approval as anexempt study.A total of 5,292 email addresses wererandomly selected by SPSS from a pool of 9,472 UPMC and Pitt patrons registered with a HSLS remote access password; 2,684 patrons from UPMC and 2,608 patrons from Pitt were selected. HSLS librarians were excluded from the survey. Participants were emailed a link to the survey in March of 2009. Three email reminders were sent at five day intervals. Data was collected for 22 days and exported from Opinio to SPSS statistics software. Survey results were analyzed using basic descriptive statistics and cross-tabulations.Main Results – Of the 5,292 emails sent, 979 surveys were submitted and 871 were completed fully. The 108 partially completed the surveys were analyzed using pair wise deletion. All HSLS user groups were represented and all

  18. Nightmare on Shaw Street: Getting Lost in Shorty’s Private Collection

    Emily Bullock

    2012-01-01

    This article discusses the semiotic and affective affordances of a regional museum on the west coast of Australia’s only island state, Tasmania. Shorty’s Private Collection is a small museum displaying items collected from around the region, with a focus on resuscitated mining materials. The owner also creates figures derived from popular culture from these items. The article uses the methodology of creative non-fiction in order to situate the museum within the marginal community ...

  19. Woman power in Corporate India In conversation with Kiran Mazumdar Shaw, Chairperson & MD, Biocon ltd

    Anitha Kurup

    2011-12-01

    Empirical evidence suggests that though women directors on Indian corporate boards show an increase both in numbers and in percentage terms, they are very much behind men. Women are also less well represented on Indian corporate boards as compared to other countries. Family ties, public sector employment and private sector banks are major sources of directorships for women. There are very few first generation women entrepreneurs in India. Though initial thresholds are higher for women to achieve success, the problems they face afterwards are similar to problems faced by successful men. India has a long way to go before women can catch up with men in the corporate world.

  20. Mitochondrial control region haplotypes of the South American sea lion Otaria flavescens (Shaw, 1800).

    Artico, L O; Bianchini, A; Grubel, K S; Monteiro, D S; Estima, S C; Oliveira, L R de; Bonatto, S L; Marins, L F

    2010-09-01

    The South American sea lion, Otaria flavescens, is widely distributed along the Pacific and Atlantic coasts of South America. However, along the Brazilian coast, there are only two nonbreeding sites for the species (Refúgio de Vida Silvestre da Ilha dos Lobos and Refúgio de Vida Silvestre do Molhe Leste da Barra do Rio Grande), both in Southern Brazil. In this region, the species is continuously under the effect of anthropic activities, mainly those related to environmental contamination with organic and inorganic chemicals and fishery interactions. This paper reports, for the first time, the genetic diversity of O. flavescens found along the Southern Brazilian coast. A 287-bp fragment of the mitochondrial DNA control region (D-loop) was analyzed. Seven novel haplotypes were found in 56 individuals (OFA1-OFA7), with OFA1 being the most frequent (47.54%). Nucleotide diversity was moderate (π = 0.62%) and haplotype diversity was relatively low (67%). Furthermore, the median joining network analysis indicated that Brazilian haplotypes formed a reciprocal monophyletic clade when compared to the haplotypes from the Peruvian population on the Pacific coast. These two populations do not share haplotypes and may have become isolated some time back. Further genetic studies covering the entire species distribution are necessary to better understand the biological implications of the results reported here for the management and conservation of South American sea lions.

  1. Mitochondrial control region haplotypes of the South American sea lion Otaria flavescens (Shaw, 1800

    L.O. Artico

    2010-09-01

    Full Text Available The South American sea lion, Otaria flavescens, is widely distributed along the Pacific and Atlantic coasts of South America. However, along the Brazilian coast, there are only two nonbreeding sites for the species (Refúgio de Vida Silvestre da Ilha dos Lobos and Refúgio de Vida Silvestre do Molhe Leste da Barra do Rio Grande, both in Southern Brazil. In this region, the species is continuously under the effect of anthropic activities, mainly those related to environmental contamination with organic and inorganic chemicals and fishery interactions. This paper reports, for the first time, the genetic diversity of O. flavescens found along the Southern Brazilian coast. A 287-bp fragment of the mitochondrial DNA control region (D-loop was analyzed. Seven novel haplotypes were found in 56 individuals (OFA1-OFA7, with OFA1 being the most frequent (47.54%. Nucleotide diversity was moderate (π = 0.62% and haplotype diversity was relatively low (67%. Furthermore, the median joining network analysis indicated that Brazilian haplotypes formed a reciprocal monophyletic clade when compared to the haplotypes from the Peruvian population on the Pacific coast. These two populations do not share haplotypes and may have become isolated some time back. Further genetic studies covering the entire species distribution are necessary to better understand the biological implications of the results reported here for the management and conservation of South American sea lions.

  2. Aplikasi Berbagai Bahan ZPT Alami untuk Meningkatkan Pertumbuhan Bibit Kemiri Sunan (Reutealis trisperma (Blanco Airy Shaw

    Fitri Kurniati

    2017-07-01

    Full Text Available Kemiri Sunan  merupakan tanaman alternatif penyediaan bahan bakar nabati dan bahan baku berbagai produk industri. Kulit benih kemiri yang keras menjadi penghalang dalam perkecambahan. Kondisi ini dapat diperbaiki dengan pemberian zat pengatur tumbuh (ZPT eksogen alami seperti umbi bawang merah sumber auksin, rebung bambu sumber giberelin, bonggol pisang dan air kelapa sebagai sumber sitokinin. Tujuan penelitian adalah mengetahui kemampuan berbagai bahan ZPT alami atau kombinasinya untuk menstimulasi perkecambahan dan pertumbuhan bibit kemiri sunan asal biji. Penelitian dilakukan pada bulan Juni sampai Oktober 2016, rancangan percobaan yaitu Rancangan Acak Kelompok yang diulang tiga kali, dengan perlakuan: a0 : kontrol (tanpa ZPT; a1 : ekstrak umbi bawang merah (BM; a2 : ekstrak rebung bambu (RB; a3: ekstrak bonggol pisang (BP;   a4 : air kelapa (AK; a5: BM + RB; a6 : BM + BP;  a7 : BM + AK; a8 : RB+ BP; a9 : RB+ AK;  a10  : BP+ AK; a11  : BM + RB + BP + AK. Hasil penelitian menunjukkan pengaruh yang berbeda terhadap daya kecambah, tinggi bibit umur 30 hari setelah tanam (HST, 37 HST, 44 HST, dan 51 HST, juga jumlah daun pada 51 HST. Aplikasi zpt BP + AK menghasilkan daya kecambah paling baik (97,78 %, namun tidak berbeda dengan aplikasi RB + BP; BM+ RB+ BP+ AK; BM + AK. Aplikasi zpt asal BP + AK menghasilkan tinggi bibit tertinggi (13,57 cm. Jumlah daun terbanyak dihasilkan pada aplikasi BP + AK (1,45 helai. Secara umum zpt bonggol pisang + air kelapa memberikan hasil paling baik, namun umbi bawang merah maupun rebung bambu mempunyai harapan untuk dikembangkan. Candlenut cv. Sunan is alternative biofuels plant also as raw of many industrial products. Its hard pulp seed becomes barrier of germination. This condition can be overcome by  giving natural plant growth regulators (PGRs, i,e shallot as auxin source, bamboo shoot as gibberellin source, banana bulb and coconut water as sources of cytokinin. The research aim was knowing effect of various PGRs and their combinations to promote germination and growth of seedling candlenut cv Sunan. The research was done from June to October 2016, in experimental design of Randomized Block Design (RBD, consisted of : a0 : control (without PGRs; a1 : shallot (BM; a2 : bamboo shoot (RB; a3: banana bulb (BP;  a4 : coconut water (AK; a5 : BM+ RB; a6 : BM + BP; a7 : BM + AK; a8 : RB+ BP;  a9 : RB + AK;  a10  : BP + AK;  a11 : BM + RB + BP + AK, all repeated three times. The result showed that application of natural PGRs had significant effect on germination percentage, plant height on 30 days after planting (dap, 37 dap, 44 dap, and 51 dap,  number of leaves 51 dap. Application of BP + AK gave the best effect on germination (97.78%, but no significant different with RB + BP; BM + RB + BP + AK. Application of BP + AK generated highest plant (13.57 cm. The best of the number of leaves was RB + AK (1.45 leaves. Overall application of natural PGRs from banana bulb + coconut water gave the best effect, besides bamboo shoot and shallot have opportunity to be developed.

  3. Environmental Impact Statement (EIS) for the Airspace Training Initiative Shaw Air Force Base, South Carolina

    2011-12-09

    wildlife; and (3) special-status species. Because of their societal and economic importance, domestic animals (e.g., cattle, sheep, hogs, poultry , and... Thomas Jefferson, High and Industrial School Sandersville Bulldog A and B MOA Georgia Washington Holt Brothers Banking Company Building...MOA Georgia Washington Madden, Charles, House Tennille Bulldog A and B MOA Georgia Washington Smith, Thomas W., House Tennille Bulldog A and B MOA

  4. Hydatid disease of the liver | Shaw | South African Journal of Surgery

    ERCP) are reserved for complicated cases. The differential diagnosis includes any cystic lesion of the liver. Liver hydatid cysts can be treated by medical or minimally invasive (laparoscopic and percutaneous) means or by conventional open ...

  5. Environmental Assessment: Construct New AAFES Shopping Center Shaw Air Force Base, South Carolina

    2008-10-01

    water supply after conventional treatment, fishing and the survival and propagation of a balanced indigenous aquatic community of flora and fauna. No...arrow-head West Indian meadow-beauty Wild petunia Amphibians Northern cricket frog Reptiles Eastern coral snake Mammals Rafinesque’s big-eared

  6. Environmental Assessment for a Fighter Detachment Facility, Shaw Air Force Base, South Carolina

    2005-04-01

    provides for the protection and propagation of fish, shellfish, wildlife, and recreation in and on the water. The US Army Corps of Engineers (USACE) is...scirpoides Long-beaked baldrush - SC Floating mats in ponds; pond margins. Ruellia caroliniensis A petunia - SC Woods and wood margins. Sagittaria...supply after conventional treatment, fishing, and the survival and propagation of a balanced indigenous aquatic Final EA for a Fighter Detachment

  7. Hydrodynamic Capture and Release of Passively Driven Particles by Active Particles Under Hele-Shaw Flows

    Mishler, Grant; Tsang, Alan Cheng Hou; Pak, On Shun

    2018-03-01

    The transport of active and passive particles plays central roles in diverse biological phenomena and engineering applications. In this paper, we present a theoretical investigation of a system consisting of an active particle and a passive particle in a confined micro-fluidic flow. The introduction of an external flow is found to induce the capture of the passive particle by the active particle via long-range hydrodynamic interactions among the particles. This hydrodynamic capture mechanism relies on an attracting stable equilibrium configuration formed by the particles, which occurs when the external flow intensity exceeds a certain threshold. We evaluate this threshold by studying the stability of the equilibrium configurations analytically and numerically. Furthermore, we study the dynamics of typical capture and non-capture events and characterize the basins of attraction of the equilibrium configurations. Our findings reveal a critical dependence of the hydrodynamic capture mechanism on the external flow intensity. Through adjusting the external flow intensity across the stability threshold, we demonstrate that the active particle can capture and release the passive particle in a controllable manner. Such a capture-and-release mechanism is desirable for biomedical applications such as the capture and release of therapeutic payloads by synthetic micro-swimmers in targeted drug delivery.

  8. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 492 (Shaw Environmental, Inc.)

    Overbay, Larry; Robitaille, George

    2005-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  9. The Inveterate Tinkerer 13. Experiments With Hele–Shaw Cells In ...

    to a linear dimension of the plates, having a fluid confined within the gap. Fluid flow in this setup ... Darcy's law [4] states that the velocity of a Newtonian fluid .... opening facing the gap, and the other end of the tube attached to a plastic microtip ...

  10. Microscopic morphology and testis morphometry of captivity-bred Adult bullfrogs (Lithobates catesbeianus Shaw, 1802

    Jaqueline Carlos

    2009-12-01

    Full Text Available The aim of this work was to study the testicular morphometry of captivity-bred adult bullfrogs. Fifteen young adult male were studied, in the rainy season and a lengthy photoperiod. The GSI was established at 0.15%. The nuclear diameter of germinative and Leydig cells, the nucleolus diameter of Sertoli cells and the area of cysts and tubules were determined and the mean number of ISPC, IISPC and SPT per cyst and the mean number of cysts per tubule was estimated. The nucleoplasmatic proportion of the nucleus of the Leydig cell was 76.22%, indicating less cytoplasmic activity. Eight generations of spermatogonia were found. The spermatogenesis efficiency in meiosis and in mitosis was 63 and 49%, respectively. The spermatogenesis of bullfrog fited in the pattern of other captivity Anurans, with differences as the morphology of Sertoli and Leydig cells nuclei.A morfometria é uma importante ferramenta para a biologia estrutural, permitindo estudos estereológicos e análises quantitativas. Existem muitos pontos a serem esclarecidos sobre a morfometria testicular desta espécie, que objetivamos desvendar neste trabalho. Quinze machos adultos foram estudados, em período chuvoso e de fotoperíodo longo (dezembro, 2000. O IGS encontrado foi de 0.15%. O diâmetro nuclear das células germinativas e da célula de Leydig, o diâmetro nucleolar das células de Sertoli e a área dos cistos e túbulos foram determinados. O número médio de ISPC, IISPC e SPT por cisto e o número médio de cisto por túbulo foi estimado. A proporção nucleoplasmática do núcleo da célula de Leydig foi de 76.22%, indicando pouca atividade citoplasmática. Oito gerações de espermatogônia foram estimadas. A eficiência da espermatogênese na meiose e mitose foi de 63% e49%, respectivamente. A espermatogênese de rãtouro segue os padrões dos demais Anuros de cativeiro, apresentando diferenças nos núcleos das c��lulas de Sertoli e Leydig.

  11. Upaya Konservasi Cendrawasih Kecil (Paradisaea minor Shaw, 1809 YANG DILAKUKAN OLEH TAMAN BURUNG TMII DAN MBOF

    Ken Dara Cita

    2016-11-01

    Full Text Available Ex situ conservation is one of the ways to save wildlife animal include lesser bird of paradise. Taman Mini Indonesia Indah (TMII Bird Park and Mega Bird And Orchid Farm (MBOF were two institutions that support ex-situ conservation program with different purposes. TMII Bird Park has non-commercial purpose breeding, while MBOF has commercial purpose in captivity breeding. The objectives of this research were to describe the management of captive breeding of lesser bird of paradise with the influencing factor for captive breeding success and the daily behavior of lesser bird of paradise in the cage. This research was conducted from March until April 2015. Focal animal sampling and one zero sampling methods were employed to observe daily behavior. The results showed that in both locations there were two kind of cages for lesser bird of paradise display cage and quarantine cage. The temperature in the TMII Bird Park display cage was 25,51⁰C, meanwhile the temperature in the MBOF display cage was 22,68⁰C. There were not differences in management between the two locations, included management of cage, feed, care and health. Two institutions did not success for captive breeding lesser bird of paradise. The behavior had been identified were: resting, ingestive, and maintenance behavior.Keywords: daily behavior, lesser bird of paradise, management of captivity

  12. Hyperbolic kaleidoscopes and Chaos in foams and Hele-Shaw cell

    Tufaile, A P B; Tufaile, A; Liger-Belair, G

    2011-01-01

    Liquid foams have fascinating optical properties, which are caused by the large number of light refractions and reflections by liquid films and Plateau borders. Due to refraction and reflection at the interfaces, the direction of the rays leaving a Plateau border can vary greatly for the same incident angle and a small positional offset. A close look in some configurations of the Plateau borders or liquid bridges reveals the existence of some triangular patterns surrounded by a complex structure, and these patterns bear a resemblance to those observed in some systems involving chaotic scattering and multiple light reflections between spheres. Provided the optical properties of the sphere surfaces are chosen appropriately, fractals are natural consequences of multiple scattering of light rays in these cavities. The cavity acts as a hyperbolic kaleidoscope multiplying the scattering of light rays generating patterns related to Poincare disks and Sierpinski gaskets in comparison to linear kaleidoscopes. We present some experimental results and simulations of these patterns explained by the light of the chaotic scattering.

  13. O efeito pigmaleão: Bernard Shaw e as releituras de os simpsons

    Sílvia Maria Guerra Anastácio

    2014-07-01

    Full Text Available http://dx.doi.org/10.5007/2175-7968.2014v1n33p287 Este artigo surgiu do interesse de estudar o efeito Pigmaleão e o modo como esse tema tem se modificado ao longo do tempo. Busca-se investigar como o mito do Pigmaleão teria dado origem a uma variedade de hipertextos que ressignificam esse objeto de análise, especialmente na mídia contemporânea, em que os episódios das séries da animação Os Simpsons dialogam

  14. Hyperbolic kaleidoscopes and Chaos in foams and Hele-Shaw cell

    Tufaile, A P B; Tufaile, A [Escola de Artes, Ciencias e Humanidades da Universidade de Sao Paulo, R. Arlindo Bettio, 1000, 03828-000, Sao Paulo (Brazil); Liger-Belair, G, E-mail: atufaile@usp.br [Laboratoire d' OEnologie et Chimie Appliquee, UPRES EA 2069, URVVC, Faculte de Sciences de Reims, Moulin de la Housse, B. P. 1039, 51687 Reims, Cedex 2 (France)

    2011-03-01

    Liquid foams have fascinating optical properties, which are caused by the large number of light refractions and reflections by liquid films and Plateau borders. Due to refraction and reflection at the interfaces, the direction of the rays leaving a Plateau border can vary greatly for the same incident angle and a small positional offset. A close look in some configurations of the Plateau borders or liquid bridges reveals the existence of some triangular patterns surrounded by a complex structure, and these patterns bear a resemblance to those observed in some systems involving chaotic scattering and multiple light reflections between spheres. Provided the optical properties of the sphere surfaces are chosen appropriately, fractals are natural consequences of multiple scattering of light rays in these cavities. The cavity acts as a hyperbolic kaleidoscope multiplying the scattering of light rays generating patterns related to Poincare disks and Sierpinski gaskets in comparison to linear kaleidoscopes. We present some experimental results and simulations of these patterns explained by the light of the chaotic scattering.

  15. Pathways to institutional equilibrium after a campus disaster / Mahauganee D. Shaw

    Shaw, Mahauganee D.

    2017-01-01

    Institutsionaalse tasakaalu sõltuvus välisteguritest ja selle võime taastuda kui asutus on veel taastumisrežiimis. Antud uuringu tulemused aitavad kaasa organisatsioonilise arengu ja kriisiohje teoreetilistele alustele, samuti kriisijuhtimise praktikale kõrghariduses

  16. AADL and Model-based Engineering

    2014-10-20

    pictures – MDE and MDA with UML – Automatically generated documents We need language for architecture modeling • Strongly typed • Well-defined...Mail Software Engineering Institute Customer Relations 4500 Fifth Avenue Pittsburgh, PA 15213-2612 USA Web Wiki.sei.cmu.edu/aadl www.aadl.info

  17. An Incremental Life-cycle Assurance Strategy for Critical System Certification

    2014-11-04

    Current practice: software modeling close to source code – Remember software through pictures – MDE and MDA with UML – Automatically generated documents...U.S. Mail Software Engineering Institute Customer Relations 4500 Fifth Avenue Pittsburgh, PA 15213-2612 USA Web Wiki.sei.cmu.edu/aadl

  18. Toward Intelligence Systems for Testing.

    1987-03-01

    corresponding to [3]. The question posed to the student will end up being, 𔄁s the current at Meter A higher, lower, or the same as the current at Meter B1 " The...List [Pittsburgh/Lesgold] NR 4422539 Dr. Diane Damos ERIC Facility-Acquisitions Arizona State University 4833 Rugby Avenue Department of Psychology

  19. Suresh, Prof. Subra

    Date of birth: 30 May 1956. Address: President, Carnegie-Mellon University, 5000, Forbes Avenue, Pittsburgh, PA 15213, U.S.A.. Contact: Office: (_1-412) 268 2200. Email: president@cmu.edu. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th ...

  20. Pittsburgh Science Technology Society Project: Instruction Modules. Interrelationships Science--Technology--Society.

    O'Brien, George, Ed.

    This collection of instruction modules studies the interactions of science, technology, and society (STS) using five activity sets. The introduction module includes activities which show students the STS relationships in their world, develop good organizational skills, develop an understanding of who and what a scientist is, develop graphing…

  1. 1967 radiation accident near Pittsburgh, Pennsylvania, and a follow-up report

    Gilberti, M.V.

    1980-01-01

    On 4 October 1967, three technicians were simultaneously accidentally exposed to whole-body radiation from a Van de Graaff linear accelerator. The accelerator generated electrons down a tube at a target of gold, where a steady stream of x-rays was produced. The clinical course, treatment of the acute and chronic changes, and the current health status of the three patients serve as the basis of this report

  2. EnviroAtlas - Pittsburgh, PA - Historic Places by Census Block Group

    U.S. Environmental Protection Agency — This EnviroAtlas dataset portrays the total number of historic places located within each Census Block Group (CBG). The historic places data were compiled from the...

  3. Evaluation of 450-MWe BGL GCC power plants fueled with Pittsburgh No. 8 coal

    Pechtl, P.A.; Chen, T.P.; Thompson, B.H.; Greil, C.F.; Niermann, S.E.; Jandrisevits, M.

    1992-11-01

    In this study, a conceptual design and cost estimate were developed for a nominal 450 MW integrated gasification combined cycle plant using the British Gas/Lurgi slagging gasification process. The present study is a design update of a previous study (EPRI Report AP-6011). The major design improvements incorporated include use of the latest GE 7F gas turbine rating, integrating the air separation plant with gas turbine, use of fuel gas saturation for NO x control, use of treated gasifier waste water as makeup water for the fuel gas saturation, and several process changes in the acid gas removal and sulfur recovery areas. Alternate design options for feeding the excess coal fines to the gasifier, treating the gasifier waste water, and the use of conventional air separation without integration with gas turbine were evaluated. The design improvements incorporated were found to increase significantly the overall plant efficiency and reduce the cost reported in the previous study. The various design options evaluated were found to have significant impacts on the plant efficiency but negligible impacts on the cost of electricity

  4. Image Understanding. Proceedings of a Workshop Held in Pittsburgh, Pennsylvania on 11-13 September, 1990

    1990-09-01

    sification of the corresponding feature vectors); or 456 permits the successful employment of a "universal" The architectural and colnputational...one To represent betweenness constraints, we need inequa - second order polynomial equation: tions. Inequations can be handled similar to equations (v-f

  5. EnviroAtlas - Pittsburgh, PA - Estimated Percent Green Space Along Walkable Roads

    U.S. Environmental Protection Agency — This EnviroAtlas dataset estimates green space along walkable roads. Green space within 25 meters of the road centerline is included and the percentage is based on...

  6. EnviroAtlas - Pittsburgh, PA - Estimated Percent Tree Cover Along Walkable Roads

    U.S. Environmental Protection Agency — This EnviroAtlas dataset estimates tree cover along walkable roads. The road width is estimated for each road and percent tree cover is calculated in a 8.5 meter...

  7. THE PITTSBURGH SLOAN DIGITAL SKY SURVEY Mg II QUASAR ABSORPTION-LINE SURVEY CATALOG

    Quider, Anna M.; Nestor, Daniel B.; Turnshek, David A.; Rao, Sandhya M.; Weyant, Anja N.; Monier, Eric M.; Busche, Joseph R.

    2011-01-01

    We present a catalog of intervening Mg II quasar absorption-line systems in the redshift interval 0.36 ≤ z ≤ 2.28. The catalog was built from Sloan Digital Sky Survey Data Release Four (SDSS DR4) quasar spectra. Currently, the catalog contains ∼17, 000 measured Mg II doublets. We also present data on the ∼44, 600 quasar spectra which were searched to construct the catalog, including redshift and magnitude information, continuum-normalized spectra, and corresponding arrays of redshift-dependent minimum rest equivalent widths detectable at our confidence threshold. The catalog is available online. A careful second search of 500 random spectra indicated that, for every 100 spectra searched, approximately one significant Mg II system was accidentally rejected. Current plans to expand the catalog beyond DR4 quasars are discussed. Many Mg II absorbers are known to be associated with galaxies. Therefore, the combination of large size and well understood statistics makes this catalog ideal for precision studies of the low-ionization and neutral gas regions associated with galaxies at low to moderate redshift. An analysis of the statistics of Mg II absorbers using this catalog will be presented in a subsequent paper.

  8. EnviroAtlas - Pittsburgh, PA - Potential Window Views of Water by Block Group

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the block group population and the percentage of the block group population that has potential views of water bodies. A potential...

  9. The Headwaters District: A History of the Pittsburgh District, U.S. Army Corps of Engineers

    1978-01-01

    four days removing a single monster pecan . By 1869, Roberts had concluded the Ohio River snagging project needed a Shreve "tooth puller ." Coal tows...Corps, for building a concrete cutoff wall upstream of the earthfill dam section. The ICOS (Impresa di Constuzioni Opere Specializate, Milano, Italy

  10. Pittsburgh Public School District / Carnegie Mellon University Robotics Team Participation in the US First Competition

    Stroupe, Ashley

    2002-01-01

    FIRST, For Inspiration and Recognition of Science and Technology, is an international program designed to encourage junior and senior high school students to participate in science and technology related activities. FIRST attempts to increase enthusiasm for technology by providing a competitive environment in which to demonstrate robotics technology designed for a particular set of tasks. Carnegie Mellon University provided student members of the project the opportunity to complete the design, construction, testing, and operation of a robot. Electrical, mechanical, and programming skills were stressed, with both adult and senior students acting as mentors for more junior members. Teamwork and integration was also stressed in order to provide students with a realistic feel for project-based work. Finally, an emphasis was placed on recruiting students with greater difficulty in entering technological fields: girls and ethnic minorities and students leaning toward humanities (especially art). Carnegie Mellon built a relationship with Taylor Allderdice High School that lasted four years. For four years, the success of the project increased each year. Each term, the students successfully designed and built a working robot that could fully participate in the competition. The enthusiasm of the students has been the cornerstone of the recruit of new students, keeping the project growing and vital. Carnegie Mellon's participation with Allderdice has been an overall great success.

  11. Requirements Engineering and Analysis Workshop Proceedings Held in Pittsburgh, Pennsylvania on 12-14 March 1991

    1991-12-01

    urally. 6.5 Summary of Current or Potential Approaches Many approaches to context analysis were discussed by the group, including: * Causal Trees * SWOT ... Apple Computer, 1988 1 Aseltine, J., Beam, W.R., Palmer, J.D., Sage, A.P., 1989, Introduction To Computer Systems: Analysis, Design and Application

  12. EnviroAtlas - Pittsburgh, PA - 51m Riparian Buffer Forest Cover

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the riparian buffer is less forested. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  13. EnviroAtlas - Pittsburgh, PA - 51m Riparian Buffer Vegetated Cover

    This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the riparian buffer is less vegetated. The displayed line represents the center of the analyzed riparian buffer. The water bodies analyzed include hydrologically connected streams, rivers, connectors, reservoirs, lakes/ponds, ice masses, washes, locks, and rapids within the Atlas Area. This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).

  14. EnviroAtlas - Pittsburgh, PA - Estimated Intersection Density of Walkable Roads

    U.S. Environmental Protection Agency — This EnviroAtlas dataset estimates the intersection density of walkable roads within a 750 meter radius of any given 10 meter pixel in the community. Intersections...

  15. Experimental particle physics at the University of Pittsburgh. Progress report, November 1, 1995--October 31, 1996

    Boudreau, J.F.; Engels, E. Jr.; Shepard, P.F.; Thompson, J.A.

    1996-05-01

    This report covers the progress on two different tasks, Task A and Task B. Task A focuses on rare and semi-rare decays of {phi} and of the short-lived kaon with emphasis on those aspects needed in preparation for the proposed {Phi}-Factory measurements of CPT violation and {epsilon}{prime}/{epsilon} from the CP-violating decays of the K{sub L}K{sub S} final state. The second aspect of the kaon decay work is participation in the so-called rare kaon decay experiments, E865, at BNL. The major goals of Task B, Fermilab program, are as follows: (1) participation in the analysis of the E706 data taken during the 1990--1991 fixed target run at Fermilab and (2) the continuation of the work with the CDF collaboration particularly the SVX II upgrade. The E706 part of the program involves the completion of publications reporting the results of the 1990--91 data run. The analysis of these data is now mature and physics results are emerging. The CDF program involves a dedicated effort to the design of a silicon vertex detector upgrade, SVX II, to be accomplished by the time Fermilab run II collider run (1999). In addition they are participating in the 1993--1995 collide run Ib and actively analyzing the data from both runs Ia and Ib.

  16. EnviroAtlas - Pittsburgh, PA - Greenspace Around Schools by Block Group

    U.S. Environmental Protection Agency — This EnviroAtlas data set shows the number of schools in each block group in the EnviroAtlas community boundary as well as the number of schools where less than 25%...

  17. Patrones reproductivos del lobo marino común, Otaria flavescens (Shaw 1800, en el centro-sur de Chile Breeding patterns in southern sea lions, Otaria flavescens (Shaw 1800, in south-central Chile

    HÉCTOR J PAVÉS

    2005-12-01

    Full Text Available El desfase latitudinal de los eventos reproductivos en Otaria flavescens sugiere la existencia de una adaptación fisiológica y conductual a condiciones ambientales locales. La identificación de cambios en los patrones conductuales intraespecíficos frente a modificaciones ambientales sugieren una relación entre estos. Se pretende revisar los patrones reproductivos del O. flavescens, determinando la existencia de una sincronización y estabilidad en ellos durante las temporadas 1996-1997 y 1997-1998 en la colonia de Punta Lobería, Chile. Se realizaron observaciones directas de las agrupaciones y conductas reproductivas empleando binoculares, y apoyadas por el uso de material fílmico y fotográfico. Los resultados evidenciaron modificaciones en, (a el número de harenes (de 28 disminuye a 19, (b la distribución espacial de los harenes (70 % de los harenes durante 1997-1998 se establecieron en el lado norte de la playa reproductiva, durante la temporada anterior estos se distribuyeron a lo largo de toda la playa, (c proporción etaria (un macho: 12 hembras: un juvenil: siete cachorros, desciende a un macho: nueve hembras: dos juveniles: seis cachorros, (d índice de poliginia (de 12,4 a 7,8 HPMT y de 11 a 9 HP, y (e la población organizada en harenes (disminución del 10,3 %. Estas variaciones estarían relacionadas con la reducción del espacio óptimo para el establecimiento de harenes debido a la incorporación de suelo/roca posterior a un derrumbe invernal. Los patrones conductuales reproductivos que se mantuvieron invariables durante las temporadas fueron, (a la estacionalidad de los harenes (constitución durante la cuarta semana de diciembre y disolución en la cuarta semana de febrero, (b el período de partos (inicio durante la segunda semana de enero, finalización durante la cuarta semana de enero, y (c el período de cópulas (inicio durante la tercera semana de enero, finalización durante la segunda semana de febrero. Por lo tanto, O. flavescens presentaría conductas modificables y permanentes que se despliegan según las condiciones ambientales. Donde las conductas reproductivas modificadas potencialmente mitigarían pérdidas en aspectos reproductivos, y las conductas reproductivas permanentes, estarían relacionadas con procesos fisiológicos y conductuales seleccionados bajo las condiciones ambientales. Estos patrones reproductivos al ser comparados con las de otras localidades son congruente con un efecto latitudinal, debido a la variación registrada tanto en la estacionalidad de ellos como en la duración de los mismos (e.g., período de partos y cópulas.The latitudinal effect of reproductive patterns for Otaria flavescens suggests the existence of behavioral and physiological adaptation to local environmental conditions. The identification of intraspecific behavioral pattern changes due to these environmental conditions suggest a relation among them. We pretend here to determine reproductive synchronization and reproductive stability of O. flavescens in the Punta Lobería colony during two breeding seasons 1996-1997 and 1997-1998. Direct observations of groups and breeding behavior were watched with binoculars backed by video and photography. Results evidenced modification in (a the number of harems (decreased from 28 to 19 during first to the second seasons, (b the spatial distribution of harems (70 % of these were located in northern part of the reproductive beach during the 1997-1998 season whereas they occupied the whole beach rather uniformly during the previous season, (c age structure (one male: 12 females: one juvenile and seven pups decreased to one male: nine females: two juveniles and six pups, (d the polygyny index (decreased from 12.4 to 7.8 HPMT and from 11 to 9 HP, and (e the reproductive population organized in harems (decreased of up to 10.3 %. These variations would be related to optimum space reduction for harem establishment after an earth/rock slide over the area. Behavioral reproductive patterns remaining stable during both seasons were (a seasonality of harems (harem formation during the fourth week in December, dissolution during the fourth week of February, (b birth period (beginning during the second week of January and ending during the fourth week of January, and (c mating period (beginning during the third week of January, ending during the second week in February. Otaria flavescens exhibited modifiable and stable behavioral patterns according to environmental conditions. Modified breeding behavior potentially would mitigate loss of reproductive output, and stable breeding behavior would be related to physiological and behavioral processes according to environmental conditions. Thus, reproductive patterns when compared to other known reproductive localities in Chile are consistent with a latitudinal effect due to variations registered by their seasonality, as well as its duration (e.g., mating and birth periods

  18. Effects of the organophosphorus pesticide Folisuper 600 (methyl parathion on the heart function of bullfrog tadpoles, Lithobates catesbeianus (Shaw, 1802

    M. J. Costa

    Full Text Available Abstract The aim of this work was to evaluate whether the heart function of bullfrog tadpoles (25 Gosner stage is affected by their acute exposure (48 h to a sub-lethal concentration (10 µg.L–1 of the active principle of the organophosphorus pesticide Folisuper 600R (methyl parathion - MP. Our results demonstrated that MP causes not only a reduction in tadpoles’ cardiac ventricular mass, resulting in a marked reduction in their cardiac twitch force, but also impairs their swimming performance, irrespective of increasing their heart rate. Together, these findings indicate that low and realistic concentration of MP have a negative impact on tadpoles’ performance, jeopardizing their survival.

  19. Final Environmental Assessment to Implement the Defense Base Closure and Realignment Commission Recommendations for Shaw Air Force Base, South Carolina

    2007-07-01

    corresponding years. Year 2005 through 2009: VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE ... VOCE * DPYII/2000 Nox (tons/yr) = NOxE * DPYII/2000 PM10(tons/yr) = PM10E * DPYII/2000 CO (tons/yr) = COE * DPYII/2000 Where: Commercial

  20. Use of feces to attract insects by a Glittering-bellied Emerald, Chlorostilbon lucidus (Shaw, 1812 (Apodiformes: Trochilidae

    Fábio André Facco Jacomassa

    2014-09-01

    Full Text Available This study describes the occurrence of a female Glittering-bellied Emerald, Chlorostilbon lucidus, using feces to attract insects to the nesting site for predation. This is the first report of a hummingbird using feces to attract insects.

  1. Critique of An Analysis of the Blast Overpressure Study Data Comparing Three Exposure Criteria, by Murphy, Khan, and Shaw

    2010-08-01

    actual determination of a risk threshold and (2) the article has laid the groundwork for such a determination. These statements misrepresent what...applied as a limit. This is a small point, but one that pervades the article and leads the authors to miss their main finding— namely, that an LAEQ8 of...WESTERN MICHIGAN UNIVERSITY G A FLAMME ASSOCIATE PROFESSOR DEPARTMENT OF SPEECH PATHOLOGY AND AUDIOLOGY 1903 W MICHIGAN AVE

  2. DOE ZERH Case Study: BrightLeaf Homes, McCormick Avenue, Brookfield, IL

    none,

    2015-09-01

    Case study of a DOE 2015 Housing Innovation Award winning production home in the cold climate that got a HERS 38 without PV, with staggered 2x4 studs every 8”on a 2x6 plate with dense-packed R-25 cellulose, basement with 3” XPS exterior and 2: XPS under slab; a vented attic with spray foam top plates and R-60 blown cellulose; 96% AFUE furnace, 14 SEER AC, plus fresh air intake.

  3. Brownfields Green Avenue Sites: Technical Memorandum - Conceptual Design for Sustainable Redevelopment

    This technical memorandum briefly describes the site and proposed conceptual site plan, indicates conceptual design considerations, specifies recommended green and sustainable features, and offers other recommendations

  4. A prediction method for job runtimes on shared processors: Survey, statistical analysis and new avenues

    Dobber, A.M.; van der Mei, R.D.; Koole, G.M.

    2007-01-01

    Grid computing is an emerging technology by which huge numbers of processors over the world create a global source of processing power. Their collaboration makes it possible to perform computations that are too extensive to perform on a single processor. On a grid, processors may connect and

  5. Neurofeedback of visual food cue reactivity: a potential avenue to alter incentive sensitization and craving.

    Ihssen, Niklas; Sokunbi, Moses O; Lawrence, Andrew D; Lawrence, Natalia S; Linden, David E J

    2017-06-01

    FMRI-based neurofeedback transforms functional brain activation in real-time into sensory stimuli that participants can use to self-regulate brain responses, which can aid the modification of mental states and behavior. Emerging evidence supports the clinical utility of neurofeedback-guided up-regulation of hypoactive networks. In contrast, down-regulation of hyperactive neural circuits appears more difficult to achieve. There are conditions though, in which down-regulation would be clinically useful, including dysfunctional motivational states elicited by salient reward cues, such as food or drug craving. In this proof-of-concept study, 10 healthy females (mean age = 21.40 years, mean BMI = 23.53) who had fasted for 4 h underwent a novel 'motivational neurofeedback' training in which they learned to down-regulate brain activation during exposure to appetitive food pictures. FMRI feedback was given from individually determined target areas and through decreases/increases in food picture size, thus providing salient motivational consequences in terms of cue approach/avoidance. Our preliminary findings suggest that motivational neurofeedback is associated with functionally specific activation decreases in diverse cortical/subcortical regions, including key motivational areas. There was also preliminary evidence for a reduction of hunger after neurofeedback and an association between down-regulation success and the degree of hunger reduction. Decreasing neural cue responses by motivational neurofeedback may provide a useful extension of existing behavioral methods that aim to modulate cue reactivity. Our pilot findings indicate that reduction of neural cue reactivity is not achieved by top-down regulation but arises in a bottom-up manner, possibly through implicit operant shaping of target area activity.

  6. Touch and Gesture-Based Language Learning: Some Possible Avenues for Research and Classroom Practice

    Reinders, Hayo

    2014-01-01

    Our interaction with digital resources is becoming increasingly based on touch, gestures, and now also eye movement. Many everyday consumer electronics products already include touch-based interfaces, from e-book readers to tablets, and from the last personal computers to the GPS system in your car. What implications do these new forms of…

  7. Metabolic disruption in context: Clinical avenues for synergistic perturbations in energy homeostasis by endocrine disrupting chemicals.

    Sargis, Robert M

    2015-01-01

    The global epidemic of metabolic disease is a clear and present danger to both individual and societal health. Understanding the myriad factors contributing to obesity and diabetes is essential for curbing their decades-long expansion. Emerging data implicate environmental endocrine disrupting chemicals (EDCs) in the pathogenesis of metabolic diseases such as obesity and diabetes. The phenylsulfamide fungicide and anti-fouling agent tolylfluanid (TF) was recently added to the list of EDCs promoting metabolic dysfunction. Dietary exposure to this novel metabolic disruptor promoted weight gain, increased adiposity, and glucose intolerance as well as systemic and cellular insulin resistance. Interestingly, the increase in body weight and adipose mass was not a consequence of increased food consumption; rather, it may have resulted from disruptions in diurnal patterns of energy intake, raising the possibility that EDCs may promote metabolic dysfunction through alterations in circadian rhythms. While these studies provide further evidence that EDCs may promote the development of obesity and diabetes, many questions remain regarding the clinical factors that modulate patient-specific consequences of EDC exposure, including the impact of genetics, diet, lifestyle, underlying disease, pharmacological treatments, and clinical states of fat redistribution. Currently, little is known regarding the impact of these factors on an individual's susceptibility to environmentally-mediated metabolic disruption. Advances in these areas will be critical for translating EDC science into the clinic to enable physicians to stratify an individual's risk of developing EDC-induced metabolic disease and to provide direction for treating exposed patients.

  8. Historical uses of saffron: Identifying potential new avenues for modern research

    Seyedeh Zeinab Mousavi

    2011-09-01

    Full Text Available Objective: During the ancient times, saffron (Crocus sativus L. had many uses around the world; however, some of these uses were forgotten throughout the history. But a newly formed interest in natural active compounds brought back the attention toward historical uses of saffron. Understanding different uses of saffron in the past can help us finding the best uses at present. In this study, we reviewed different uses of saffron throughout the history among different nations.Methods: ISI web of Science and Medline, along with references of traditional Iranian medicine were searched for historical uses of saffron.Results: Saffron has been known since more than 3000 years ago by many nations. It was valued not only as a culinary condiment, but also as a dye, perfume and as a medicinal herb. Its medicinal uses ranged from treating eye problems to genitourinary and many other diseases in various cultures. It was also used as a tonic agent and antidepressant drug among many nations. Conclusion(s: Saffron has had many different uses such as a food additive and a palliative agent for many human diseases. Thus, as an important medicinal herb, it is a good candidate with many promising potentials to be considered for new drug design.

  9. 1 Annexure 1 Indian Academy of Sciences C V Raman Avenue ...

    CHITRA

    Indian Academy of Sciences. C V Raman ... Please justify your suitability for the position applied, in not more than 150 words : 10. Give below the names of three references (they must not be related to you) who are in a position to testify from ...

  10. Profiting from empowerment? Investigating dissemination avenues for educational technology content within an emerging market solutions project

    P.A. Arora (Payal)

    2005-01-01

    textabstractABSTRACT: The Stills in Sync (SIS) project is a joint initiative of the nonprofit organization PlanetRead and the global information and communication technology (ICT) company Hewlett Packard (HP). The SIS project entails creating a multimedia product designed to enhance literacy in

  11. Gediminas Avenue and Apranga clothing set real-estate, retail records

    2004-01-01

    Londoni kinnisvarakontserni Cushman & Wakefield Healey & Baker koostatud maailma peatänavate uuringust selgus, et Baltimaade kalleim ostutänav on Gediminase avenüü Vilniuses. Maailma pingereas on Gediminase avenüü 37. kohal, Viru tänav 44. ja Krasta tänav Riias on 45. kohal

  12. Image of Women in Advertisements: A Preliminary Study of Avenues for Change.

    Butler-Paisley, Matilda, Ed.; And Others

    The Center for Research on Women (CROW) at Stanford University along with the Communication Department, the Psychology Department, and the School of Education conducted a study on the image of women in advertising and suggested ways to improve women's image in the advertising media. With the objective of sponsoring some alternatives to expedite…

  13. A tale of Persian cupping therapy: 1001 potential applications and avenues for research.

    Bamfarahnak, Hossein; Azizi, Amir; Noorafshan, Ali; Mohagheghzadeh, Abdolali

    2014-01-01

    Cupping therapy (CT) is one of the oldest medical techniques available, and is still used in several cultures instead of or as an adjunct or complement to 'western academic' medicine. Moreover, CT (wet or dry) is claimed to have therapeutic effects in many types of disorders which do not fully respond to conventional medicine or for which no effective treatment is available. However, no recent reviews of the clinical practice of cupping are available to the best of our knowledge. We describe the applications of CT as used in Traditional Iranian Medicine (TIM). Several databases were searched for relevant literature. In addition, we studied the main traditional treatises on TIM regarding the history and practice of CT. Information about current practices was obtained from a systematic survey among practitioners. Our results suggest that CT is currently prescribed for up to 120 diseases and disorders that are difficult to treat, including cutaneous (21.7%), musculoskeletal (15%), and central nervous system (13.3%) disorders. Moreover, TIM treatises note 25 specific sites on the body surface which correspond to certain diseases, and on which wet-cupping therapy has therapeutic effects. Additional clinical studies of CT may lead to findings on new therapeutic methods and may shed light on mechanisms of disease and illness that are not fully understood in conventional medicine. © 2014 S. Karger GmbH, Freiburg.

  14. Gene expression profiling in MDS and AML: potential and future avenues

    Theilgaard-Mönch, K; Boultwood, J; Ferrari, S

    2011-01-01

    Today, the classification systems for myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) already incorporate cytogenetic and molecular genetic aberrations in an attempt to better reflect disease biology. However, in many MDS/AML patients no genetic aberrations have been identified yet...... with regard to diagnosis, prediction of clinical outcome, discovery of novel subclasses and identification of novel therapeutic targets and novel drugs. As many challenges remain ahead, we discuss the pitfalls of this technology and its potential including future integrative studies with other genomics...

  15. Aggression, Violence and Injury in Minor League Ice Hockey: Avenues for Prevention of Injury.

    Michael D Cusimano

    Full Text Available In North America, more than 800,000 youth are registered in organized ice hockey leagues. Despite the many benefits of involvement, young players are at significant risk for injury. Body-checking and aggressive play are associated with high frequency of game-related injury including concussion. We conducted a qualitative study to understand why youth ice hockey players engage in aggressive, injury-prone behaviours on the ice.Semi-structured interviews were conducted with 61 minor ice hockey participants, including male and female players, parents, coaches, trainers, managers and a game official. Players were aged 13-15 playing on competitive body checking teams or on non-body checking teams. Interviews were manually transcribed, coded and analyzed for themes relating to aggressive play in minor ice hockey.Parents, coaches, teammates and the media exert a large influence on player behavior. Aggressive behavior is often reinforced by the player's social environment and justified by players to demonstrate loyalty to teammates and especially injured teammates by seeking revenge particularly in competitive, body-checking leagues. Among female and male players in non-body checking organizations, aggressive play is not reinforced by the social environment. These findings are discussed within the framework of social identity theory and social learning theory, in order to understand players' need to seek revenge and how the social environment reinforces aggressive behaviors.This study provides a better understanding of the players' motivations and environmental influences around aggressive and violent play which may be conducive to injury. The findings can be used to help design interventions aimed at reducing aggression and related injuries sustained during ice hockey and sports with similar cultures and rules.

  16. Brief Communication : Future avenues for permafrost science from the perspective of early career researchers

    Fritz, M.; Deshpande, B. N.; Bouchard, F.; Högström, E.; Malenfant-Lepage, J.; Morgenstern, A.; Nieuwendam, A.; Oliva, M.; Paquette, M.; Rudy, A. C A; Siewert, M. B.; Sjöberg, Y.; Weege, S.

    2015-01-01

    Accelerating climate change and increased economic and environmental interests in permafrost-affected regions have resulted in an acute need for more directed permafrost research. In June 2014, 88 early career researchers convened to identify future priorities for permafrost research. This

  17. Grassland-cropping rotations: An avenue for agricultural diversification to reconcile high production with environmental quality

    A need to increase agricultural production across the world to ensure continued food security appears to be at odds with the urgency to reduce the negative environmental impacts of intensive agriculture. Around the world, intensification has been associated with massive simplification and uniformity...

  18. Grassland-Cropping Rotations: An Avenue for Agricultural Diversification to Reconcile High Production with Environmental Quality.

    Lemaire, Gilles; Gastal, François; Franzluebbers, Alan; Chabbi, Abad

    2015-11-01

    A need to increase agricultural production across the world to ensure continued food security appears to be at odds with the urgency to reduce the negative environmental impacts of intensive agriculture. Around the world, intensification has been associated with massive simplification and uniformity at all levels of organization, i.e., field, farm, landscape, and region. Therefore, we postulate that negative environmental impacts of modern agriculture are due more to production simplification than to inherent characteristics of agricultural productivity. Thus by enhancing diversity within agricultural systems, it should be possible to reconcile high quantity and quality of food production with environmental quality. Intensification of livestock and cropping systems separately within different specialized regions inevitably leads to unacceptable environmental impacts because of the overly uniform land use system in intensive cereal areas and excessive N-P loads in intensive animal areas. The capacity of grassland ecosystems to couple C and N cycles through microbial-soil-plant interactions as a way for mitigating the environmental impacts of intensive arable cropping system was analyzed in different management options: grazing, cutting, and ley duration, in order to minimize trade-offs between production and the environment. We suggest that integrated crop-livestock systems are an appropriate strategy to enhance diversity. Sod-based rotations can temporally and spatially capture the benefits of leys for minimizing environmental impacts, while still maintaining periods and areas of intensive cropping. Long-term experimental results illustrate the potential of such systems to sequester C in soil and to reduce and control N emissions to the atmosphere and hydrosphere.

  19. Food Commensals as a Potential Major Avenue in Transmitting Antibiotic Resistance Genes

    Lehman, Mark W; Wang, Hua H; Manuzon, Michele; Wan, Kai; Luo, Hongliang; Wittum, Tom; Yousef, Ahmed; Bakaletz, Lauren O

    2005-01-01

    ...(to the seventh power) CFU per gram of product. The presence of large populations of ART bacteria in these foods, particularly in many ready-to-eat "health" food items, indicates that the ART bacteria are abundant...

  20. Retinitis pigmentosa-associated cystoid macular oedema: pathogenesis and avenues of intervention

    Strong, S; Liew, G; Michaelides, M

    2017-01-01

    Hereditary retinal diseases are now the leading cause of blindness certification in the working age population (age 16–64 years) in England and Wales, of which retinitis pigmentosa (RP) is the most common disorder. RP may be complicated by cystoid macular oedema (CMO), causing a reduction of central vision. The underlying pathogenesis of RP-associated CMO (RP-CMO) remains uncertain, however, several mechanisms have been proposed, including: (1) breakdown of the blood-retinal barrier, (2) failure (or dysfunction) of the pumping mechanism in the retinal pigment epithelial, (3) Müller cell oedema and dysfunction, (4) antiretinal antibodies and (5) vitreous traction. There are limited data on efficacy of treatments for RP-CMO. Treatments attempted to date include oral and topical carbonic anhydrase inhibitors, oral, topical, intravitreal and periocular steroids, topical non-steroidal anti-inflammatory medications, photocoagulation, vitrectomy with internal limiting membrane peel, oral lutein and intravitreal antivascular endothelial growth factor injections. This review summarises the evidence supporting these treatment modalities. Successful management of RP-CMO should aim to improve both quality and quantity of vision in the short term and may also slow central vision loss over time. PMID:27913439

  1. A new avenue for classification and prediction of olive cultivars using supervised and unsupervised algorithms.

    Amir H Beiki

    Full Text Available Various methods have been used to identify cultivares of olive trees; herein we used different bioinformatics algorithms to propose new tools to classify 10 cultivares of olive based on RAPD and ISSR genetic markers datasets generated from PCR reactions. Five RAPD markers (OPA0a21, OPD16a, OP01a1, OPD16a1 and OPA0a8 and five ISSR markers (UBC841a4, UBC868a7, UBC841a14, U12BC807a and UBC810a13 selected as the most important markers by all attribute weighting models. K-Medoids unsupervised clustering run on SVM dataset was fully able to cluster each olive cultivar to the right classes. All trees (176 induced by decision tree models generated meaningful trees and UBC841a4 attribute clearly distinguished between foreign and domestic olive cultivars with 100% accuracy. Predictive machine learning algorithms (SVM and Naïve Bayes were also able to predict the right class of olive cultivares with 100% accuracy. For the first time, our results showed data mining techniques can be effectively used to distinguish between plant cultivares and proposed machine learning based systems in this study can predict new olive cultivars with the best possible accuracy.

  2. La titrisation de la dette interieure de l'etat : une avenue prometteuse ...

    Une recension des écrits, non exhaustive mais assez suffisante a permis de relever, à travers cet article, que la titrisation est bien une stratégie de financement, qu'elle peut corriger les crises de liquidité et régler la dette nette. Elle a donc une utilité certaine pour les entreprises et les Etats en période de tension de trésorerie ...

  3. Avenues to improve success in SME business transfers: reflections on theories, research and policies

    Lex van Teeffelen

    2012-01-01

    Every year I talk to many entrepreneurs about business transfers and acquisitions. Only rarely do they tell me that it was a cinch. Buying or selling a business is complex. For a start, a business should be shipshape from an organizational and administrative perspective, while several legal

  4. Formal education as an avenue for community action on climate change

    Cordero, E.

    2017-12-01

    Green Ninja started at San Jose State University as an educational initiative to inspire youth action on climate change. We created educational videos, games and lesson plans that promoted climate science literacy and pro-environmental behavior. Although some teachers found our content valuable, we came to learn that the overriding decisions about course curriculum come from the school district level. Should we want to scale in a manner that might really provide an environmental benefit, we needed to learn about school district needs and to develop a product that solves their problems. This presentation will discuss our journey from value propositions to empathy for our clients, and how we came to realize that the best approach for achieving our common goals was through the commercial marketplace. We will share data from some of our early adopters that suggests that formal education can both achieve district goals while also delivering environmental benefits. We will also describe the value of partnerships and how leveraging support from communities with aligning interests are improving our chances of success.

  5. Human reliability and human factors in complex organizations: epistemological and critical analysis - practical avenues to action

    Llory, A.

    1991-08-01

    This article starts out with comment on the existence of persistent problems inherent to probabilistic safety assessments (PSA). It first surveys existing American documents on the subject which make a certain number of criticisms on human reliability analyses, e.g. limitations due to the scant quantities of data available, lack of a basic theoretical model, non-reproducibility of analyses, etc. The article therefore examines and criticizes the epistemological bases of these analyses. One of the fundamental points stressed is that human reliability analyses do not take account of all the special features of the work situation which result in human error (so as to draw up statistical data from a sufficiently representative number of cases), and consequently lose all notion of the 'relationships' between human errors and the different aspects of the working environment. The other key points of criticism concern the collective nature of work which is not taken into account, and the frequent confusion between what operatives actually do and their formally prescribed job-tasks. The article proposes aspects to be given thought in order to overcome these difficulties, e.g. quantitative assessment of the social environment within a company, non-linear model for assessment of the accident rate, analysis of stress levels in staff on off-shore platforms. The method approaches used in these three studies are of the same type, and could be transposed to human-reliability problems. The article then goes into greater depth on thinking aimed at developing a 'positive' view of the human factor (and not just a 'negative' one, i.e. centred on human errors and organizational malfunctions), applying investigation methods developed in the occupational human sciences (occupational psychodynamics, ergonomics, occupational sociology). The importance of operatives working as actors of a team is stressed

  6. An Avenue for Challenging Sexism: Examining the High School Sociology Classroom

    Kaylene Mae Stevens

    2016-03-01

    Full Text Available In this interpretative qualitative study, the researchers investigated the beliefs and practices of six high school sociology teachers in relation to the teaching of gender. Using a feminist lens, this study employed mixed methods, analyzing teacher interviews, observations, and classroom artifacts. The results showed that the teachers viewed sociology as different from other social studies courses, because it serves as a more intentional way to reduce sexism and gender stratification. As such, the teachers saw the sociology classroom as a place for students to grapple with issues of gender stratification and inequity.  Teachers’ beliefs related to gender and sexism strongly influenced what they saw as the purpose of sociology class, and it influenced the instructional practices that they used.  Recommendations are made related to professional development around issues of gender equity.

  7. Potential avenues for exercise to activate episodic memory-related pathways: a narrative review.

    Loprinzi, Paul D; Edwards, Meghan K; Frith, Emily

    2017-09-01

    Memory function plays an important role in activities of daily living, and consequently, quality and quantity of life. In this narrative review, we discuss the anatomical components of episodic memory, including the structure of the hippocampus and the routes of communication to and from this structure. We also highlight cellular traces of memory, such as the engram cell and pathway. To provide etiological insight, the biological mechanisms of episodic memory are discussed, including factors subserving memory encoding (e.g., cognitive attention, neuroelectrical indices), consolidation (i.e., synaptic and brain systems level), and retrieval (e.g., availability of cues, context-dependent, state-dependent, and cognitive processing). Central to this manuscript, we highlight how exercise may influence each of these aforementioned parameters (e.g., exercise-induced hippocampal growth, synaptic plasticity, and cue retrieval) and then discuss the implications of these findings to enhance and preserve memory function. Collectively, this narrative review briefly summarizes potential mechanisms of episodic memory, and how exercise may activate these mechanistic pathways. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  8. An Alternative Avenue to Teacher Certification: A Cost Analysis of the Pathways to Teaching Careers Program.

    Rice, Jennifer King; Brent, Brian O.

    2002-01-01

    Analyzes cost effectiveness of the Pathways to Teaching Careers, a program that supports an alternative route to university-based teacher certification primarily for noncertified teachers, paraprofessionals, and Peace Corps volunteers. (PKP)

  9. A facile avenue to conductive polymer brushes via cyclopentadiene-maleimide Diels-Alder ligation

    Yameen, B.; Rodriguez-Emmenegger, C.; Preuss, C. M.; Pop-Georgievski, Ognen; Verveniotis, Elisseos; Trouillet, V.; Rezek, Bohuslav; Barner-Kowollik, C.

    2013-01-01

    Roč. 49, č. 77 (2013), s. 8623-8625 ISSN 1359-7345 R&D Projects: GA ČR GBP205/12/G118; GA ČR GAP108/11/1857; GA ČR(CZ) GBP108/12/G108 Institutional support: RVO:61389013 ; RVO:68378271 Keywords : conductive poly(3-hexylthiophen) brushes * Diels-Alder ligation * Kelvin Probe Force Microscopy (KFM) Subject RIV: CD - Macromolecular Chemistry Impact factor: 6.718, year: 2013

  10. Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease.

    Chitramuthu, Babykumari P; Bennett, Hugh P J; Bateman, Andrew

    2017-12-01

    Progranulin, a secreted glycoprotein, is encoded in humans by the single GRN gene. Progranulin consists of seven and a half, tandemly repeated, non-identical copies of the 12 cysteine granulin motif. Many cellular processes and diseases are associated with this unique pleiotropic factor that include, but are not limited to, embryogenesis, tumorigenesis, inflammation, wound repair, neurodegeneration and lysosome function. Haploinsufficiency caused by autosomal dominant mutations within the GRN gene leads to frontotemporal lobar degeneration, a progressive neuronal atrophy that presents in patients as frontotemporal dementia. Frontotemporal dementia is an early onset form of dementia, distinct from Alzheimer's disease. The GRN-related form of frontotemporal lobar dementia is a proteinopathy characterized by the appearance of neuronal inclusions containing ubiquitinated and fragmented TDP-43 (encoded by TARDBP). The neurotrophic and neuro-immunomodulatory properties of progranulin have recently been reported but are still not well understood. Gene delivery of GRN in experimental models of Alzheimer's- and Parkinson's-like diseases inhibits phenotype progression. Here we review what is currently known concerning the molecular function and mechanism of action of progranulin in normal physiological and pathophysiological conditions in both in vitro and in vivo models. The potential therapeutic applications of progranulin in treating neurodegenerative diseases are highlighted. © The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. Teamwork in skull base surgery: An avenue for improvement in patient care.

    McLaughlin, Nancy; Carrau, Ricardo L; Kelly, Daniel F; Prevedello, Daniel M; Kassam, Amin B

    2013-01-01

    During the past several decades, numerous centers have acquired significant expertise in the treatment of skull base pathologies. Favorable outcomes are not only due to meticulous surgical planning and execution, but they are also related to the collaborative efforts of multiple disciplines. We review the impact of teamwork on patient care, elaborate on the key processes for successful teamwork, and discuss its challenges. Pubmed and Medline databases were searched for publications from 1970 to 2012 using the following keywords: "teamwork", "multidisciplinary", "interdisciplinary", "surgery", "skull base", "neurosurgery", "tumor", and "outcome". Current literature testifies to the complexity of establishing and maintaining teamwork. To date, few reports on the impact of teamwork in the management of skull base pathologies have been published. This lack of literature is somewhat surprising given that most patients with skull base pathology receive care from multiple specialists. Common factors for success include a cohesive and well-integrated team structure with well-defined procedural organization. Although a multidisciplinary work force has clear advantages for improving today's quality of care and propelling research efforts for tomorrow's cure, teamwork is not intuitive and requires training, guidance, and executive support. Teamwork is recommended to improve quality over the full cycle of care and consequently patient outcomes. Increased recognition of the value of an integrated team approach for skull base pathologies will hopefully encourage centers, physicians, allied health caregivers, and scientists devoted to treating these patients and advancing the field of knowledge to invest the time, effort, and resources to optimize and organize their collective expertise.

  12. Reaching adolescent girls through social networking: a new avenue for smoking prevention messages.

    Struik, Laura Louise; Bottorff, Joan L; Jung, Mary; Budgen, Claire

    2012-09-01

    Because adolescent girls are being targeted on social networking sites by the tobacco industry, new online tobacco control (TC) initiatives are needed. The purpose of this interpretive descriptive study was to explore adolescent girls' perspectives on the use of social networking sites to deliver TC messages targeting young women. Focus groups were conducted with 17 girls aged 16 to 19. Seven TC messages were provided for evaluation and as context for discussion about the delivery of TC messages on social networking sites. Data were analyzed for themes, which included concerns about the effectiveness of current TC messages and the stereotypical representations of gender, factors perceived to influence the effectiveness of TC messages on social networking sites, and suggestions for enhancing the effectiveness of TC messages placed on social networking sites. Endorsement of TC messaging on social networking sites suggests that this medium is an untapped resource for smoking prevention.

  13. Monitoring Fatigue Status with HRV Measures in Elite Athletes: An Avenue Beyond RMSSD?

    Schmitt, Laurent; Regnard, Jacques; Millet, Grégoire P.

    2015-01-01

    Among the tools proposed to assess the athlete's “fatigue,” the analysis of heart rate variability (HRV) provides an indirect evaluation of the settings of autonomic control of heart activity. HRV analysis is performed through assessment of time-domain indices, the square root of the mean of the sum of the squares of differences between adjacent normal R-R intervals (RMSSD) measured during short (5 min) recordings in supine position upon awakening in the morning and particularly the logarithm of RMSSD (LnRMSSD) has been proposed as the most useful resting HRV indicator. However, if RMSSD can help the practitioner to identify a global “fatigue” level, it does not allow discriminating different types of fatigue. Recent results using spectral HRV analysis highlighted firstly that HRV profiles assessed in supine and standing positions are independent and complementary; and secondly that using these postural profiles allows the clustering of distinct sub-categories of “fatigue.” Since, cardiovascular control settings are different in standing and lying posture, using the HRV figures of both postures to cluster fatigue state embeds information on the dynamics of control responses. Such, HRV spectral analysis appears more sensitive and enlightening than time-domain HRV indices. The wealthier information provided by this spectral analysis should improve the monitoring of the adaptive training-recovery process in athletes. PMID:26635629

  14. New avenues for regulation of lipid metabolism by thyroid hormones and analogs.

    Senese, Rosalba; Lasala, Pasquale; Leanza, Cristina; de Lange, Pieter

    2014-01-01

    Weight loss due to negative energy balance is a goal in counteracting obesity and type 2 diabetes mellitus. The thyroid is known to be an important regulator of energy metabolism through the action of thyroid hormones (THs). The classic, active TH, 3,5,3'-triiodo-L-thyronine (T3) acts predominantly by binding to nuclear receptors termed TH receptors (TRs), that recognize TH response elements (TREs) on the DNA, and so regulate transcription. T3 also acts through "non-genomic" pathways that do not necessarily involve TRs. Lipid-lowering therapies have been suggested to have potential benefits, however, the establishment of comprehensive therapeutic strategies is still awaited. One drawback of using T3 in counteracting obesity has been the occurrence of heart rhythm disturbances. These are mediated through one TR, termed TRα. The end of the previous century saw the exploration of TH mimetics that specifically bind to TR beta in order to prevent cardiac disturbances, and TH derivatives such as 3,5-diiodo-L-thyronine (T2), that possess interesting biological activities. Several TH derivatives and functional analogs have low affinity for the TRs, and are suggested to act predominantly through non-genomic pathways. All this has opened new perspectives in thyroid physiology and TH derivative usage as anti-obesity therapies. This review addresses the pros and cons of these compounds, in light of their effects on energy balance regulation and on lipid/cholesterol metabolism.

  15. New Avenues for Regulation of Lipid Metabolism by Thyroid Hormones and Analogs

    Rosalba eSenese

    2014-12-01

    Full Text Available Weight loss due to negative energy balance is a goal in counteracting obesity and type 2 diabetes mellitus. The thyroid is known to be an important regulator of energy metabolism through the action of thyroid hormones (THs. The classic, active TH, 3,5,3’-triiodo-L-thyronine (T3 acts predominantly by binding to nuclear receptors termed TH receptors (TRs, that recognize TH response elements (TREs on the DNA, and so regulate transcription. T3 also acts through non-genomic pathways that do not necessarily involve TRs. Lipid-lowering therapies have been suggested to have potential benefits, however, the establishment of comprehensive therapeutic strategies is still awaited. One drawback of using T3 in counteracting obesity has been the occurrence of heart rhythm disturbances. These are mediated through one TR, termed TR alpha. The end of the previous century saw the exploration of TH mimetics that specifically bind to TR beta in order to prevent cardiac disturbances, and TH derivatives such as 3,5-diiodo-L-thyronine (T2, that possess interesting biological activities. Several TH derivatives and functional analogs have low affinity for the TRs, and are suggested to act predominantly through non-genomic pathways. All this has opened new perspectives in thyroid physiology and TH derivative usage as anti-obesity therapies. This review addresses the pros and cons of these compounds, in light of their effects on energy balance regulation and on lipid/cholesterol metabolism.

  16. Mount Tabor Care Centre, Newgrove Avenue, Sandymount Green, Sandymount, Dublin 4.

    E M O’Connor, E M

    2017-11-01

    Traditionally, surgery and certain surgical sub-specialities in particular have been predominantly male orientated. In recent years, there has been an increased proportion of female medical graduates which will ultimately have an effect on speciality choices. The aim of this study was to assess the gender diversity among urologists in the UK and Ireland. The total number and gender breakdown of consultant urologists and trainees in the UK and Ireland was obtained from the British Association of Urological Surgeons (BAUS) and the Irish Society of Urology (ISU) membership offices. The total number and gender breakdown of medical school entrants and graduates in 2015 was obtained from the six medical schools in the Republic of Ireland. There are a total of 1,012 consultant urologists in the UK and Ireland. In the UK, 141 (14.6%) are female compared to four (8.2%) in Ireland, p= 0.531. There was a significant increase in the number of females between consultant urologists and trainees in both the UK (p=0.0001) and Ireland (p=0.015). In recent years, there has been a significant change in the percentage of female trainees in the UK and Ireland (22.8% (n=75) in 2011 vs 31.7% (n=93) in 2014, p=0.019. Between the six medical schools in Ireland, there were significantly more female entrants (n=726, 56.5%) than female graduates (n=521, 51.2%) in 2015, p=0.013.There has been a significant shift in gender diversity in urology in the UK and Ireland. Efforts to increase diversity should be pursued to attract further trainees to urology.

  17. Technology: Student Animation Projects: An Avenue to Promote Creativity and Learning

    Siegle, Del

    2014-01-01

    Using readily available technology, students of all ages can easily create impressive animated products. Animation allows educators to capitalize on the natural desire that students of all ages hold to tell stories and share their understanding of the world. In the course of planning their animations, students conduct research on topics, organize…

  18. Radiological re-survey results at 130 West Central Avenue, Maywood, New Jersey (MJ029)

    Murray, M.E.; Johnson, C.A.

    1994-01-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from 1916 to 1959. During the early years of operation, MCW stored wastes and residues in low-lying areas west of the processing facilities and consequently some of the residuals containing radioactive materials migrated offsite to the surrounding area. Subsequently, the U.S. Department of Energy (DOE), designated for remedial action the old MCW property and several vicinity properties. Additionally, in 1984, the property at 130 West Central Ave., Maywood, New Jersey and properties in its vicinity were included as a decontamination research and development project under the DOE Formerly Utilized Sites Remedial Action Program. In 1987 and 1988, at the request of DOE, ORNL conducted a radiological survey on this property. A second radiological survey by ORNL was conducted on this property in May, 1993 at the request of DOE after an ad hoc radiological survey, requested by a new property owner and conducted by Bechtel National, Inc. (BNI), identified some contamination not previously found by ORNL. The purpose of the survey was to determine if residuals from the old MCW were present on the property, and if so, if any radiological elements present were above guidelines. A certified civil survey was requisitioned by ORNL to determine actual property boundaries before beginning the radiological survey. The radiological re-survey included a surface gamma scan and the collection of a large number of soil samples for radionuclide analyses

  19. Art as an Avenue to Science Literacy: Teaching Nanotechnology through Stained Glass

    Duncan, Kimberly A.; Johnson, Chris; McElhinny, Kyle; Ng, Steve; Cadwell, Katie D.; Zenner Petersen, Greta M.; Johnson, Angela; Horoszewski, Dana; Gentry, Ken; Lisensky, George; Crone, Wendy C.

    2010-01-01

    Nanoscale science and engineering (NSE) and nanotechnology are emerging fields that have captured the attention of scientists and engineers, as well as mainstream media. However, the general public is relatively unaware of NSE, and schools (both K-12 and undergraduate institutions) rarely include nanotechnology as part of their curriculum. To help…

  20. Effect of plant extracts on Alzheimer′s disease: An insight into therapeutic avenues

    M Obulesu

    2011-01-01

    Full Text Available Alzheimer′s disease (AD is a devastative neurodegenerative disorder which needs adequate studies on effective treatment options. The extracts of plants and their effect on the amelioration of AD symptoms have been extensively studied. This paper summarizes the mechanisms like acetylcholinesterase (AChE inhibition, modification of monoamines, antiamyloid aggregation effect, and antioxidant activity which are actively entailed in the process of amelioration of AD symptoms. These effects are induced by extracts of a few plants of different origin like Yizhi Jiannao, Moringa oleifera (Drumstick tree, Ginkgo Biloba (Ginkgo/Maidenhair tree, Cassia obtisufolia (Sicklepod, Desmodium gangeticum (Sal Leaved Desmodium, Melissa officinalis (Lemon Balm, and Salvia officinalis (Garden sage, common sage.

  1. Intraosseouss degenerative cyst of the axis approached via transcervical extrapharyngeal avenue

    Gustavo Rassier Isolan

    2012-01-01

    Full Text Available Intraosseous degenerative cysts (IDC of the cervical spine are rare. IDC within C2 have been reported in three articles only. We report a patient with neck pain due to a IDC within C2. We discuss the differential diagnosis of these lesions and the surgical approaches to reach this complex anatomical region.

  2. Nuclear Avenue: “Cyclonic Development”, Abandonment, and Relations in Uranium City, Canada

    Robert Boschman

    2018-01-01

    Full Text Available The rise and abandonment of Uranium City constitutes an environmental history yet to be fully evaluated by humanities scholars. 1982 marks the withdrawal of the Eldorado Corporation from the town and the shuttering of its uranium mines. The population declined to approximately 50 from its pre-1982 population of about 4000. This article is inspired by findings from the authors’ initial field visit. As Uranium City is accessible only by air or by winter roads across Lake Athabasca, the goal of the visit in May 2017 was to gather information and questions through photographic assessment and through communication and interviews with residents. This paper in part argues that the cyclonic development metaphor used to describe single-commodity communities naturalizes environmental damage and obscures a more complicated history involving human agency. Apart from the former mines that garner remedial funding and action, the town site of Uranium City is also of environmental concern. Its derelict suburbs and landfill, we also argue, could benefit from assessment, funding, and remediation. Canada’s 2015 Truth and Reconciliation Commission Report provides a way forward in healing this region, in part by listening to the voices of those most affected by environmental impacts caused not by a metaphorical cyclone but by other humans’ decisions. As descendants of European immigrants to Turtle Island (the Indigenous term referring to North America, the authors are also subjects of the very terms—cyclonic development, abandonment, remediation—used to describe the history of the land itself: in this case, a mining town in the far northern boreal forests and Precambrian Shield.

  3. Palladium(0) NHC complexes : a new avenue to highly efficient phosphorescence

    Henwood, Adam Francis; Lesieur, Mathieu; Bansal, Ashu Kumar; Lemaur, Vincent; Beljonne, David; Thompson, David G.; Graham, Duncan; Slawin, Alexandra Martha Zoya; Samuel, Ifor David William; Cazin, Catherine S.J.; Zysman-Colman, Eli

    2015-01-01

    The authors are grateful to the Royal Society (University Research Fellowship to CSJC and Wolfson Research Merit Award for IDWS) and to EPSRC (grant: EP1J01771X) for financial support. EZ-C thanks the University of St Andrews for funding. We report the first examples of highly luminescent di-coordinated Pd(0) complexes. Five complexes of the form [Pd(L)(L’)] were synthesized, where L = IPr, SIPr or IPr* NHC ligands and L’ = PCy3, or IPr and SIPr NHC ligands. The photophysical properties of...

  4. Palladium(0) NHC complexes: a new avenue to highly efficient phosphorescence.

    Henwood, Adam F; Lesieur, Mathieu; Bansal, Ashu K; Lemaur, Vincent; Beljonne, David; Thompson, David G; Graham, Duncan; Slawin, Alexandra M Z; Samuel, Ifor D W; Cazin, Catherine S J; Zysman-Colman, Eli

    2015-05-01

    We report the first examples of highly luminescent di-coordinated Pd(0) complexes. Five complexes of the form [Pd(L)(L')] were synthesized, where L = IPr, SIPr or IPr* NHC ligands and L' = PCy 3 , or IPr and SIPr NHC ligands. The photophysical properties of these complexes were determined in degassed toluene solution and in the solid state and contrasted to the poorly luminescent reference complex [Pd(IPr)(PPh 3 )]. Organic light-emitting diodes were successfully fabricated but attained external quantum efficiencies of between 0.3 and 0.7%.

  5. Pathogenic aspects and therapeutic avenues of intestinal fibrosis in Crohn's disease.

    Zorzi, Francesca; Calabrese, Emma; Monteleone, Giovanni

    2015-12-01

    In Crohn's disease, one of the two major forms of inflammatory bowel diseases in human beings, persistent and chronic inflammation promotes fibrotic processes thereby facilitating formation of strictures, the most common indication for surgical intervention in this disorder. The pathogenesis of Crohn's disease-associated fibrosis is not fully understood, but variants of genes involved in the recognition of microbial components/products [e.g. CARD15 (caspase-activating recruitment domain 15) and ATG16L1 (autophagy-related 16-like 1)] are associated with this phenotype, and experimental evidence suggests that intestinal fibrosis results from an altered balance between deposition of ECM (extracellular matrix) and degradation of ECM by proteases. Studies have also contributed to identify the main phenotypic and functional alterations of cells involved in the fibrogenic process, as well as molecules that stimulate such cells to produce elevated amounts of collagen and other ECM-related proteins. In the present review, we assess the current knowledge about cellular and molecular mediators of intestinal fibrosis and describe results of recent studies aimed at testing the preventive/therapeutic effect of compounds in experimental models of intestinal fibrosis. © 2015 Authors; published by Portland Press Limited.

  6. Clinical correlates of faecal incontinence in systemic sclerosis: identifying therapeutic avenues.

    Richard, Nicolas; Hudson, Marie; Gyger, Geneviève; Baron, Murray; Sutton, Evelyn; Khalidi, Nader; Pope, Janet E; Carrier, Nathalie; Larché, Maggie; Albert, Alexandra; Fortin, Paul R; Thorne, Carter; Masetto, Ariel

    2017-04-01

    The aim was to establish the prevalence and severity of faecal incontinence (FI) in SSc, its association with other intestinal manifestations and potential predictors of FI, and its impact on quality of life. A multicentre, cross-sectional study of 298 SSc subjects followed in the Canadian Scleroderma Research Group cohort was performed using validated questionnaires: Jorge-Wexner score (an FI severity scale), Bristol stool scale (a visual scale of stool consistency) and FI Quality-of-Life scale. Constipation was defined by the Rome III criteria. Associations between the Jorge-Wexner score and other clinical variables were determined using multivariate regression analyses. Eighty-one (27.2%) subjects had FI, which was mild in 37 (12.4%) and moderate to severe in 44 (14.8%). Most patients had well-formed stools, 111 (38.8%) reported constipation and 38 (13.4%) had been previously treated for small intestinal bacterial overgrowth (SIBO). Variables independently associated with FI were: loose vs well-formed stools [odds ratio (OR) = 7.01, 95% CI: 2.09, 23.51)], constipation (OR = 3.64, 95% CI: 1.61, 8.27, P = 0.002), history of SIBO (OR = 2.97, 95% CI: 1.06, 8.27) and urinary incontinence (OR = 2.45, 95% CI: 1.14, 5.27). Quality of life measured with the FI Quality-of-Life scale was inversely correlated with FI severity (correlation coefficients between -0.602 and -0.702, P < 0.001). FI was common and often severe in SSc. Loose stools, SIBO, constipation and urinary incontinence were strongly associated with FI. Other than targeting anorectal dysfunction, concomitant treatment of clinical correlates could lead to improvement in FI and quality of life in SSc. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  7. Integrating movement ecology with biodiversity research-exploring new avenues to address spatiotemporal biodiversity dynamics

    Jeltsch, F.; Bonte, D.; Pe'er, G.; Reineking, B.; Leimgruber, P.; Balkenhol, N.; Schröder, B.; Buchmann, C.M.; Mueller, T.; Blaum, N.; Zurell, D.; Böhning-Gaese, K.; Wiegand, T.; Eccard, J.A.; Hofer, H.; Reeg, J.; Eggers, U.; Bauer, S.

    2013-01-01

    Movement of organisms is one of the key mechanisms shaping biodiversity, e.g. the distribution of genes, individuals and species in space and time. Recent technological and conceptual advances have improved our ability to assess the causes and consequences of individual movement, and led to the

  8. MaxSynBio - Avenues towards creating cells from the bottom up.

    Schwille, Petra; Spatz, Joachim; Landfester, Katharina; Bodenschatz, Eberhard; Herminghaus, Stephan; Sourjik, Victor; Erb, Tobias; Bastiaens, Philippe; Lipowsky, Reinhard; Hyman, Anthony; Dabrock, Peter; Baret, Jean-Christophe; Vidakovic-Koch, Tanja; Bieling, Peter; Dimova, Rumiana; Mutschler, Hannes; Robinson, Tom; Tang, Dora; Wegner, Seraphine; Sundmacher, Kai

    2018-05-11

    A large Max Planck-based German research consortium ('MaxSynBio') was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom-up approach to Synthetic Biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life, via their modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non-living components. The fundamental insights gained from the activities in MaxSynBio can eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace natural cells currently used in conventional biotechnology. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. An Avenue for Challenging Sexism: Examining the High School Sociology Classroom

    Stevens, Kaylene Mae; Martell, Christopher C.

    2016-01-01

    In this interpretative qualitative study, the researchers investigated the beliefs and practices of six high school sociology teachers in relation to the teaching of gender. Using a feminist lens, this study employed mixed methods, analyzing teacher interviews, observations, and classroom artifacts. The results showed that the teachers viewed…

  10. [Media coverage of suicide: From the epidemiological observations to prevention avenues].

    Notredame, Charles-Édouard; Pauwels, Nathalie; Walter, Michel; Danel, Thierry; Vaiva, Guillaume

    2015-12-01

    Media coverage of suicide can result in increased morbi-mortality suicidal rates, due to an imitation process in those who are particularly vulnerable. This phenomenon is known as "Werther effect". Werther effect's magnitude depends on several qualitative and quantitative characteristics of the media coverage, in a dose-effect relationship. An extensive (in terms of audience and history repetition) and salient coverage (glorification of suicide, description of the suicidal method, etc.) increases the risk of contagion. Celebrities' suicide is particularly at risk of Werther effect. Media may also have a preventive role with respect to suicide. Indeed, according to "Papageno effect", journalists could, under certain conditions, help preventing suicide when reporting suicide stories. Two main theories in the field of social psychology have been proposed to account for Werther and Papageno effects: social learning theory and differential identification. Identification of Werther and Papageno effects uncovers new responsibilities and potentialities for the journalists in terms of public health. Their description provides a basis for promising targeted prevention actions. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  11. Aggression, Violence and Injury in Minor League Ice Hockey: Avenues for Prevention of Injury.

    Cusimano, Michael D; Ilie, Gabriela; Mullen, Sarah J; Pauley, Christopher R; Stulberg, Jennifer R; Topolovec-Vranic, Jane; Zhang, Stanley

    2016-01-01

    In North America, more than 800,000 youth are registered in organized ice hockey leagues. Despite the many benefits of involvement, young players are at significant risk for injury. Body-checking and aggressive play are associated with high frequency of game-related injury including concussion. We conducted a qualitative study to understand why youth ice hockey players engage in aggressive, injury-prone behaviours on the ice. Semi-structured interviews were conducted with 61 minor ice hockey participants, including male and female players, parents, coaches, trainers, managers and a game official. Players were aged 13-15 playing on competitive body checking teams or on non-body checking teams. Interviews were manually transcribed, coded and analyzed for themes relating to aggressive play in minor ice hockey. Parents, coaches, teammates and the media exert a large influence on player behavior. Aggressive behavior is often reinforced by the player's social environment and justified by players to demonstrate loyalty to teammates and especially injured teammates by seeking revenge particularly in competitive, body-checking leagues. Among female and male players in non-body checking organizations, aggressive play is not reinforced by the social environment. These findings are discussed within the framework of social identity theory and social learning theory, in order to understand players' need to seek revenge and how the social environment reinforces aggressive behaviors. This study provides a better understanding of the players' motivations and environmental influences around aggressive and violent play which may be conducive to injury. The findings can be used to help design interventions aimed at reducing aggression and related injuries sustained during ice hockey and sports with similar cultures and rules.

  12. Potential Avenues for Significant Biofuels Penetration in the U.S. Aviation Market

    Newes, Emily [National Renewable Energy Lab. (NREL), Golden, CO (United States); Han, Jeongwoo [Argonne National Lab. (ANL), Argonne, IL (United States); Peterson, Steve [Lexidyne LLC, Colorado Springs, CO (United States)

    2017-04-01

    Industry associations have set goals to reduce greenhouse gas (GHG) emissions and increase fuel efficiency. One focal area for reducing GHG emissions is in the use of aviation biofuel. This study examines assumptions under which the United States could see large production in aviation biofuel. Our results suggest that a high penetration (6 billion gallons) of aviation biofuels by 2030 could be possible, but factors around policy design (in the absence of high oil prices) contribute to the timing and magnitude of aviation biofuels production: 1) Incentives targeted towards jet fuel production such as financial incentives (e.g., producer tax credit, carbon tax) can be sufficient; 2) Investment in pre-commercial cellulosic technologies is needed to reduce the cost of production through learning-by-doing; 3) Reduction of investment risk through loan guarantees may allow production to ramp up more quickly through accelerating industry learning. In cases with high levels of incentives and investment in aviation biofuels, there could be a 25 percent reduction in overall GHG emissions from the aviation sector.

  13. We Turned to Madison Avenue for Tips on Selling Our $64 Million Bond Issue.

    Conyers, John G.; Francl, Terry

    1989-01-01

    An Illinois school system won a bond issue election with a 30-day marketing campaign. Helpful marketing practices include identification of the target audience and finding the best medium to reach the audience. (MLF)

  14. The Future of Bronchopulmonary Dysplasia: Emerging Pathophysiological Concepts and Potential New Avenues of Treatment

    Jennifer J. P. Collins

    2017-05-01

    Full Text Available Yearly more than 15 million babies are born premature (<37 weeks gestational age, accounting for more than 1 in 10 births worldwide. Lung injury caused by maternal chorioamnionitis or preeclampsia, postnatal ventilation, hyperoxia, or inflammation can lead to the development of bronchopulmonary dysplasia (BPD, one of the most common adverse outcomes in these preterm neonates. BPD patients have an arrest in alveolar and microvascular development and more frequently develop asthma and early-onset emphysema as they age. Understanding how the alveoli develop, and repair, and regenerate after injury is critical for the development of therapies, as unfortunately there is still no cure for BPD. In this review, we aim to provide an overview of emerging new concepts in the understanding of perinatal lung development and injury from a molecular and cellular point of view and how this is paving the way for new therapeutic options to prevent or treat BPD, as well as a reflection on current treatment procedures.

  15. Radiological re-survey results at 146 West Central Avenue, Maywood, New Jersey (MJ034)

    Murray, M.E.; Johnson, C.A.

    1994-05-01

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from 1916 to 1959. During the early years of operation, MCW stored wastes and residues in low-lying areas west of the processing facilities and consequently some of the residuals containing radioactive materials migrated offsite to the surrounding area. Subsequently, the U.S. Department of Energy (DOE) designated for remedial action the old MCW property and several vicinity properties. Additionally, in 1984, the property at 146 West Central Ave., Maywood, New Jersey and properties in its vicinity were included as a decontamination research and development project under the DOE Formerly Utilized Sites Remedial Action Program. In 1987 and 1988, at the request of DOE, Oak Ridge National Laboratory (ORNL) conducted a radiological survey on this property. A report describing this survey was published in 1989. A second radiological survey by ORNL was conducted on this property in May 1993 at the request of DOE after an ad hoc radiological survey, requested by the property owner and conducted by Bechtel National, Inc. (BNI), identified some contamination not previously found by ORNL. The purpose of the second ORNL survey was to determine whether radioactive materials from the old MCW were present on the property, and if so, if radioactive materials present were above guidelines. A certified civil survey was requisitioned by ORNL to determine actual property boundaries before beginning the radiological re-survey. The re-survey included a surface gamma scan and the collection of a large number of soil samples for radionuclide analyses. Results of this survey demonstrated that although elevated residual thorium-232 contamination was present in a few isolated spots on the southern end of the backyard, it did not exceed DOE guidelines

  16. Holidays in the Public School Kindergarten: An Avenue for Emerging Religious and Spiritual Literacy.

    Myers, Michal Elaine; Myers, Barbara Kimes

    2002-01-01

    Addresses holidays in the curriculum and concerns raised for educators about how to be inclusive and recognize students' different cultures. Presents a sample approach to exploring holidays in the classroom, including techniques for brainstorming, celebration activities, children's individual experiences, expanding experiences, engaging families,…

  17. American Indian internet cigarette sales: another avenue for selling tobacco products.

    Hodge, Felicia S; Geishirt Cantrell, Betty A; Struthers, Roxanne; Casken, John

    2004-02-01

    A study conducted by the University of Minnesota found that cigarettes can be purchased on American Indian-owned Internet sites for about one fifth of the price at grocery stores, making this a more convenient, lower-priced, and appealing method of purchasing cigarettes. Researchers and educators are challenged to address this new marketing ploy and to discover ways to curb rising smoking rates in American Indian communities.

  18. Suggested avenues to reduce the stigma of mental illness in the Middle East.

    Sewilam, Ahmed M; Watson, Annie M M; Kassem, Ahmed M; Clifton, Sue; McDonald, Margaret C; Lipski, Rebecca; Deshpande, Smita; Mansour, Hader; Nimgaonkar, Vishwajit L

    2015-03-01

    Stigma toward mentally ill individuals acts as a barrier to accessing care and receiving treatment. To review current evidence pertaining to stigma toward mental illness in the Middle East in order to inform effective and sustainable interventions in this region. We conducted a systematic literature search using the PubMed database and evaluated all identified studies according to specific inclusion criteria. Stigma toward individuals with mental illness does exist in the Middle East. Stigmatizing attitudes are particularly high toward culturally proscribed mental illnesses like alcohol abuse and lower for other disorders such as depression and psychosis. We propose the following initiatives to reduce stigma toward mental illness in the Middle East: (a) educate families to enable them to support their affected relatives, (b) increase cooperation between psychiatrists and faith healers and (c) educate young people in schools to increase their awareness and understanding of mental illnesses and to combat negative stereotypes. © The Author(s) 2014.

  19. Historical uses of saffron: Identifying potential new avenues for modern research

    Seyedeh Zeinab Mousavi

    2011-09-01

    Full Text Available Objective: During the ancient times, saffron (Crocus sativus L. had many uses around the world; however, some of these uses were forgotten throughout the history. But a newly formed interest in natural active compounds brought back the attention toward historical uses of saffron. Understanding different uses of saffron in the past can help us finding the best uses at present.In this study, wereviewed different uses of saffron throughout the history among different nations. Methods: ISI web of Science and Medline, along with references of traditional Iranian medicine were searched for historical uses of saffron. Results: Saffron has been known since more than 3000 years ago by many nations. It was valued not only as a culinary condiment, but also as a dye, perfume and as a medicinal herb. Its medicinal uses ranged from treating eye problems to genitourinary and many other diseases in various cultures. It was also used as a tonic agent and antidepressant drug among many nations. Conclusion(s: Saffron has had many different uses such as a food additive and a palliative agent for many human diseases. Thus, as an important medicinal herb, it is a good candidate with many promising potentials to be considered for new drug design.

  20. Targeting S1P in Inflammatory bowel disease: new avenues for modulating intestinal leukocyte migration.

    Danese, Silvio; Furfaro, Federica; Vetrano, Stefania

    2017-07-28

    Sphingosine 1 phosphate (S1P) is a bioactive lipid mediator involved in the regulation of several cellular processes though the activation of a G protein-coupled receptor family known as the S1P receptors (S1PRs). Advances in the understanding of the biological activities mediated by S1PRs have sparked great interest in the S1P/S1PRs axes as new therapeutic targets for the modulation of several cellular processes. In particular, S1P/ S1PR1 axis has been identified as key regulator for the lymphocyte migration from lymph nodes. The blockade of this axis is emerging as a new therapeutic approach to control the aberrant leukocytes migration into the mucosa in inflammatory bowel disease (IBD). This review briefly summarizes the current evidence coming from clinical studies and discusses the future prospects of S1P inhibitors for treatment of inflammatory bowel disease. Copyright © 2017 European Crohn’s and Colitis Organisation (ECCO). Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  1. Mobile shopper marketing: Key issues, current insights, and future research avenues

    Shankar, V.; Kleijnen, M.H.P.; Ramanathan, S.; Rizley, R.; Holland, S.; Morrissey, S.

    2016-01-01

    The intersection of mobile marketing and shopper marketing, known as mobile shopper marketing, is a rapidly evolving area. We formally define mobile shopper marketing as the planning and execution of all mobile-based marketing activities that influence a shopper along and beyond the

  2. Indian Academy of Sciences C V Raman Avenue, Bengaluru 560 080

    ias

    Technology, Government of India proposes to fill up the following permanent positions : ... Computer knowledge and familiarity of using E-mail programmes, ... Candidates already in government service should forward their application through ...

  3. Review article: the gut microbiome in inflammatory bowel disease-avenues for microbial management.

    McIlroy, J; Ianiro, G; Mukhopadhya, I; Hansen, R; Hold, G L

    2018-01-01

    The concept of an altered collective gut microbiota rather than identification of a single culprit is possibly the most significant development in inflammatory bowel disease research. We have entered the "omics" era, which now allows us to undertake large-scale/high-throughput microbiota analysis which may well define how we approach diagnosis and treatment of inflammatory bowel disease (IBD) in the future, with a strong steer towards personalised therapeutics. To assess current epidemiological, experimental and clinical evidence of the current status of knowledge relating to the gut microbiome, and its role in IBD, with emphasis on reviewing the evidence relating to microbial therapeutics and future microbiome modulating therapeutics. A Medline search including items 'intestinal microbiota/microbiome', 'inflammatory bowel disease', 'ulcerative colitis', 'Crohn's disease', 'faecal microbial transplantation', 'dietary manipulation' was performed. Disease remission and relapse are associated with microbial changes in both mucosal and luminal samples. In particular, a loss of species richness in Crohn's disease has been widely observed. Existing therapeutic approaches broadly fall into 3 categories, namely: accession, reduction or indirect modulation of the microbiome. In terms of microbial therapeutics, faecal microbial transplantation appears to hold the most promise; however, differences in study design/methodology mean it is currently challenging to elegantly translate results into clinical practice. Existing approaches to modulate the gut microbiome are relatively unrefined. Looking forward, the future of microbiome-modulating therapeutics looks bright with several novel strategies/technologies on the horizon. Taken collectively, it is clear that ignoring the microbiome in IBD is not an option. © 2017 John Wiley & Sons Ltd.

  4. Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson’s Disease

    Sudhakar R. Subramaniam

    2017-06-01

    Full Text Available Parkinson’s disease (PD is a chronic and progressive disorder characterized neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular proteinaceous inclusions, reduction of dopaminergic terminals in the striatum, and increased neuroinflammatory cells. The consequent reduction of dopamine in the basal ganglia results in the classical parkinsonian motor phenotype. A growing body of evidence suggest that neuroinflammation mediated by microglia, the resident macrophage-like immune cells in the brain, play a contributory role in PD pathogenesis. Microglia participate in both physiological and pathological conditions. In the former, microglia restore the integrity of the central nervous system and, in the latter, they promote disease progression. Microglia acquire different activation states to modulate these cellular functions. Upon activation to the M1 phenotype, microglia elaborate pro-inflammatory cytokines and neurotoxic molecules promoting inflammation and cytotoxic responses. In contrast, when adopting the M2 phenotype microglia secrete anti-inflammatory gene products and trophic factors that promote repair, regeneration, and restore homeostasis. Relatively little is known about the different microglial activation states in PD and a better understanding is essential for developing putative neuroprotective agents. Targeting microglial activation states by suppressing their deleterious pro-inflammatory neurotoxicity and/or simultaneously enhancing their beneficial anti-inflammatory protective functions appear as a valid therapeutic approach for PD treatment. In this review, we summarize microglial functions and, their dual neurotoxic and neuroprotective role in PD. We also review molecules that modulate microglial activation states as a therapeutic option for PD treatment.

  5. DOE ZERH Case Study: Heirloom Design Build, Euclid Avenue, Atlanta, GA

    none,

    2015-09-01

    Case study of a DOE 2015 Housing Innovation Award winning custom home in the mixed-humid climate that got a HERS 50 without PV, with 2x6 16” on center walls with R-19 ocsf; basement with R-28 ccsf, R-5 rigid foam under slab; sealed attic with R-28 ocsf under roof deck; 22.8 SEER; 12.5 HSPF heat pump.

  6. SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK: NEW AVENUES OF TREATMENT?

    T. Braunschweig

    2013-01-01

    Full Text Available Squamous cell carcinoma of the head and neck counts for 3 % of all cancers in men and half of this number less in women with a 5-year survival of 61 %. While the number of laryngeal carcinoma is decreasing, carcinoma of the oral cavity related to an infection by the human papilloma virus (HPV, high-risk subtypes is increasing, especially in younger patients. HPV related squamous cell carcinomas show better survival data, especially in regard to recurrence free rates or secondary carcinoma of adjacent locations. Squamous cell carcinomas related to the presence of HPV DNA material is almost exclusively found in carcinoma of the oral cavity and oropharyngeal mucosa. Much less frequently HPV is present in hypopharyngeal carcinomas and even less number of cases of squamous cell carcinoma with proof for HPV in the nasopharynx and larynx. In case of evidence for HPV DNA; most cases are positively tested for subtype 16, followed by subtype 18. As a surrogate immunhistochemical marker, p16 INK4A is stained positive, cytoplasmic and nuclear. In a small study by ourselves, we found a positive correlation in 100 % of p16 INK4A positivity and positive HPV testing. Oral squamous cell carcinoma is more frequently related to HPV in patients below 50 years of age with a prevalence of ca. 20 %. Whilst HPV high-risk positive carcinomas show very few mutations in single signalling molecules of the downstream receptor tyrosin kinase pathways, HPV negative carcinomas show in many cases a chaotic DNA mutation type with typical mutations in tumor suppressor genes, as p53 and CDKN2A. This pattern is often seen in carcinoma types develop from a summation of accidental mutations often caused by toxins (e.g. inhaled cigarette smoke. However, it is discussed and under investigation whether a subset of head and neck squamous cell carcinomasdevelop from so called driver mutations, as are called mutations in critical members of signalling pathways and receptor tyrosin kinases, e. g. FGF receptors, PTEN, PIK3CA. In a similar group of squamous cell carcinomas, those of the lower airways, trachea, bronchi and lung parenchyma, also massively caused by inhaled toxins, a subset of 20 % show these driver mutations. Tumors with driver mutations, especially related to tyrosin kinases and depending pathways are eligible for small molecule therapeutics, inhibitors of tyrosin kinases and signalling kinases, e. g. Erlotinib in EGF receptor or Vemurafininb for B-RAF. There is much need for further stratification of head and neck squamous cell carcinoma to introduce the wide field of inhibitors at least to a subset of these patients.

  7. Can the American High School become an Avenue of Advancement for All?

    Balfanz, Robert

    2009-01-01

    As the twenty-first century opens, says Robert Balfanz, the United States is developing a deep social consensus that American high schools should ensure that all adolescents graduate from high school prepared for postsecondary schooling and training. Balfanz asks how well high schools are succeeding in this mission and whether they can ultimately…

  8. Avenues for Scientist Involvement in Planetary Science Education and Public Outreach

    Shipp, S. S.; Buxner, S.; Cobabe-Ammann, E. A.; Dalton, H.; Bleacher, L.; Scalice, D.

    2012-12-01

    The Planetary Science Education and Public Outreach (E/PO) Forum is charged by NASA's Science Mission Directorate (SMD) with engaging, extending, and supporting the community of E/PO professionals and scientists involved in planetary science education activities in order to help them more effectively and efficiently share NASA science with all learners. A number of resources and opportunities for involvement are available for planetary scientists involved in - or interested in being involved in - E/PO. The Forum provides opportunities for community members to stay informed, communicate, collaborate, leverage existing programs and partnerships, and become more skilled education practitioners. Interested planetary scientists can receive newsletters, participate in monthly calls, interact through an online community workspace, and attend annual E/PO community meetings and meetings of opportunity at science and education conferences. The Forum also provides professional development opportunities on a myriad of topics, from common pre-conceptions in planetary science to program evaluation, to delivering effective workshops. Thematic approaches, such as the Year of the Solar System (http://solarsystem.nasa.gov/yss), are coordinated by the Forum; through these efforts resources are presented topically, in a manner that can be easily ported into diverse learning environments. Information about the needs of audiences with which scientists interact - higher education, K-12 education, informal education, and public - currently is being researched by SMD's Audience-Based Working Groups. Their findings and recommendations will be made available to inform the activities and products of E/PO providers so they are able to better serve these audiences. Also in production is a "one-stop-shop" of SMD E/PO products and resources that can be used in conjunction with E/PO activities. Further supporting higher-education efforts, the Forum coordinates a network of planetary science faculty, bringing them together at science conferences to share resources and experiences and to discuss pertinent education research. An online higher education clearinghouse, (EarthSpace - http://www.lpi.usra.edu/earthspace), has been developed to provide faculty with news and funding information, the latest education research and resources for teaching undergraduates, and undergraduate course materials, including lectures, labs, and homework. The presentation will explore the Planetary Science E/PO Forum pathways and tools available to support scientists involved in - or interested in being involved in - E/PO.

  9. Avenues for Scientist Involvement in Earth and Space Science Education and Public Outreach (Invited)

    Peticolas, L. M.; Gross, N. A.; Hsu, B. C.; Shipp, S. S.; Buxner, S.; Schwerin, T. G.; Smith, D.; Meinke, B. K.

    2013-12-01

    NASA's Science Mission Directorate (SMD) Science Education and Public Outreach (E/PO) Forums are charged with engaging, extending, supporting, and coordinating the community of E/PO professionals and scientists involved in Earth and space science education activities. This work is undertaken to maximize the effectiveness and efficiency of the overall national NASA science education and outreach effort made up of individual efforts run by these education professionals. This includes facilitating scientist engagement in education and outreach. A number of resources and opportunities for involvement are available for scientists involved in - or interested in being involved in - education or outreach. The Forums provide opportunities for earth and space scientists to stay informed, communicate, collaborate, leverage existing programs and partnerships, and become more skilled education practitioners. Interested scientists can receive newsletters, participate in monthly calls, interact through an online community workspace, and attend E/PO strategic meetings. The Forums also provide professional development opportunities on a myriad of topics, from common pre-conceptions in science, to program evaluation, to delivering effective workshops. Thematic approaches, such as Earth Science Week (http://www.earthsciweek.org), and the Year of the Solar System (http://solarsystem.nasa.gov/yss) are coordinated by the Forums; through these efforts resources are presented topically, in a manner that can be easily ported into diverse learning environments. Information about the needs of audiences with which scientists interact - higher education, K-12 education, informal education, and public - are provided by SMD's Audience-Based Working Groups. Their findings and recommendations are made available to inform the activities and products of E/PO providers so they are able to better serve these audiences. Also available is a 'one-stop shop' of SMD E/PO products and resources that can be used in conjunction with E/PO activities, NASA Wavelength (http://nasawavelength.org). Further supporting higher-education efforts, the Forums coordinate a network of science faculty, bringing them together at science conferences to share resources and experiences and to discuss pertinent education research. An online higher education clearinghouse, EarthSpace (http://www.lpi.usra.edu/earthspace), has been developed to provide faculty with news and funding information, the latest education research and resources for teaching undergraduates, and undergraduate course materials, including lectures, labs, and homework. This presentation will explore the Science E/PO Forums' pathways and tools available to support scientists involved in - or interested in being involved in - E/PO.

  10. New Cloud and Precipitation Research Avenues Enabled by low-cost Phased-array Radar Technology

    Kollias, P.; Oue, M.; Fridlind, A. M.; Matsui, T.; McLaughlin, D. J.

    2017-12-01

    For over half a century, radars operating in a wide range of frequencies have been the primary source of observational insights of clouds and precipitation microphysics and dynamics and contributed to numerous significant advancements in the field of cloud and precipitation physics. The development of multi-wavelength and polarization diversity techniques has further strengthened the quality of microphysical and dynamical retrievals from radars and has assisted in overcoming some of the limitations imposed by the physics of scattering. Atmospheric radars have historically employed a mechanically-scanning dish antenna and their ability to point to, survey, and revisit specific points or regions in the atmosphere is limited by mechanical inertia. Electronically scanned, or phased-array, radars capable of high-speed, inertialess beam steering, have been available for several decades, but the cost of this technology has limited its use to military applications. During the last 10 years, lower power and lower-cost versions of electronically scanning radars have been developed, and this presents an attractive and affordable new tool for the atmospheric sciences. The operational and research communities are currently exploring phased array advantages in signal processing (i.e. beam multiplexing, improved clutter rejection, cross beam wind estimation, adaptive sensing) and science applications (i.e. tornadic storm morphology studies). Here, we will present some areas of atmospheric research where inertia-less radars with ability to provide rapid volume imaging offers the potential to advance cloud and precipitation research. We will discuss the added value of single phased-array radars as well as networks of these radars for several problems including: multi-Doppler wind retrieval techniques, cloud lifetime studies and aerosol-convection interactions. The performance of current (dish) and future (e-scan) radar systems for these atmospheric studies will be evaluated using numerical model output and a sophisticated radar simulator package.

  11. Double pharmacological challenge on repolarization opens new avenues for drug safety research

    Thomsen, Morten Bækgaard

    2007-01-01

    pointes (TdP) arrhythmia. Both the pharmaceutical industry and the regulatory bodies are neglecting the available proarrhythmia models. In vitro studies have suggested that combined pharmacological hits on repolarization will produce a superior substrate for in vivo proarrhythmia, compared to the single......-drug assessment. By using consecutive pharmacological challenges, a simple model is proposed, in which combinatorial pharmacology is employed to provoke TdP in the conscious dog. The pharmaceutical industry interested in evaluating the proarrhythmic potential of their present and future drugs now has a simple...

  12. Enlisting Madison Avenue: The Marketing Approach to Earning Popular Support in Theaters of Operation

    2007-01-01

    likely vary considerably from their rural counterparts in terms of media consumption habits. Resource availability and reli- ance on traditional PSYOP TTP...asked its executives to write customized letters to a list of social nodes from media outlets who cover ecommerce -related industries. The social

  13. The principle(s) of co-existence in Europe: Social, economic and legal avenues

    Purnhagen, K.; Wesseler, J.H.H.

    2015-01-01

    The European policy of coexistence follows a number of well-established social, economic and legal principles. Applying these principles in practice has resulted in a complex “rag rug” of coexistence policies in Europe. This rag rug makes enforcement of these principles difficult, at times even

  14. Hazelwood Interim Storage Site environmental report for calendar year 1992, 9200 Latty Avenue, Hazelwood, Missouri

    1993-05-01

    This report describes the environmental surveillance program at the Hazelwood Interim storage Site (HISS) and surrounding area, provides the results for 1992, and discusses applicable environmental standards and requirements with which the results were compared. HISS is located in eastern Missouri in the City of Hazelwood (St. Louis County) and occupies approximately 2.2 ha (5.5 acres). Environmental monitoring of HISS began in 1984 when the site was assigned to the US Department of Energy (DOE) as part of the decontamination research and development project authorized by Congress under the 1984 Energy and Water Development Appropriations Act. DOE placed responsibility for HISS under the Formerly Utilized Sites Remedial Action Program (FUSRAP), which was established to identify and decontaminate or otherwise control sites where residual radioactive materials remain from the early years of the nation`s atomic energy program or from commercial operations causing conditions that Congress has authorized DOE to remedy. In 1992 there were no environmental occurrences or unplanned contaminant releases as defined in DOE requirements and in the Superfund Amendment and Reauthorization Act (SARA) Title III of CERCLA.

  15. E-selling: A new avenue of research for service design and online engagement

    Parvinen, P.; Oinas-Kukkonen, H.; Kaptein, M.C.

    2015-01-01

    E-selling is an activity that is distinct from e-commerce, e-marketing and e-retailing. E-selling is conceptualized to be computer–human dialog characterized by the digital spatio-temporal locus, the psychology of online persuasion, and complex perceptions of value. This definition warrants that

  16. E-selling : A new avenue of research for service design and online engagement

    Parvinen, Petri; Oinas-Kukkonen, Harri; Kaptein, M.C.

    2015-01-01

    E-selling is an activity that is distinct from e-commerce, e-marketing and e-retailing. E-selling is conceptualized to be computer–human dialog characterized by the digital spatio-temporal locus, the psychology of online persuasion, and complex perceptions of value. This definition warrants that

  17. Middlesex Sampling Plant environmental report for calendar year 1992, 239 Mountain Avenue, Middlesex, New Jersey

    1993-05-01

    This report describes the environmental surveillance program at the Middlesex Sampling Plant (MSP) and provides the results for 1992. The site, in the Borough of Middlesex, New Jersey, is a fenced area and includes four buildings and two storage piles that contain 50,800 m 3 of radioactive and mixed hazardous waste. More than 70 percent of the MSP site is paved with asphalt. The MSP facility was established in 1943 by the Manhattan Engineer District (MED) to sample, store, and/or ship uranium, thorium, and beryllium ores. In 1955 the Atomic Energy Commission (AEC), successor to MED, terminated the operation and later used the site for storage and limited sampling of thorium residues. In 1967 AEC activities ceased, onsite structures were decontaminated, and the site was certified for unrestricted use under criteria applicable at that time. In 1980 the US Department of Energy (DOE) initiated a multiphase remedial action project to clean up several vicinity properties onto which contamination from the plant had migrated. Material from these properties was consolidated into the storage piles onsite. Environmental surveillance of MSP began in 1980 when Congress added the site to DOE's Formerly Utilized Sites Remedial Action Program. The environmental surveillance program at MSP includes sampling networks for radon and thoron in air; external gamma radiation exposure; and radium-226, radium-228, thorium-230, thorium-232, and total uranium in surface water, sediment, and groundwater. Additionally, chemical analyses are performed to detect metals and organic compounds in surface water and groundwater and metals in sediments. This program assists in fulfilling th DOE policy of measuring and monitoring effluents from DOE activities and calculating hypothetical doses

  18. Colonie Interim Storage Site environmental report for calendar year 1992, 1130 Central Avenue, Colonie, New York

    1993-05-01

    This report describes the environmental surveillance program at the Colonie Interim Storage Site (CISS) and provides the results for 1992. The site is located in eastern New York State, approximately 6.4 km (4.0 mi) northwest of downtown Albany. From 1958 to 1984, National Lead (NL) Industries used the facility to manufacture various components from depleted and enriched uranium natural thorium. Environmental monitoring of CISS began in 1984 when Congress added, the site to the US Department of Energy's (DOE) Formerly Utilized Sites Remedial Action Program (FUSRAP). FUSRAP is a program established to identify and decontaminate or otherwise control sites where residual radioactive materials remain from the early years of the nation's atomic energy program or from commercial operations causing conditions that Congress has authorized DOE to remedy. The environmental surveillance program at CISS includes sampling networks for external gamma radiation exposure and for thorium-232 and total uranium concentrations in surface water, sediment, and groundwater. Several chemical parameters are also measured in groundwater, including total metals, volatile organics, and water quality parameters. This surveillance program assists in fulfilling the DOE policy of measuring and monitoring effluents from DOE activities and calculating hypothetical doses. Results are compared with applicable Environmental Protection Agency (EPA) and New York State Department of Environmental Conservation (NYSDEC) standards, DOE derived concentration guides (DCGs), dose limits, and other DOE requirements

  19. Hazelwood Interim Storage Site environmental report for calendar year 1992, 9200 Latty Avenue, Hazelwood, Missouri

    1993-05-01

    This report describes the environmental surveillance program at the Hazelwood Interim storage Site (HISS) and surrounding area, provides the results for 1992, and discusses applicable environmental standards and requirements with which the results were compared. HISS is located in eastern Missouri in the City of Hazelwood (St. Louis County) and occupies approximately 2.2 ha (5.5 acres). Environmental monitoring of HISS began in 1984 when the site was assigned to the US Department of Energy (DOE) as part of the decontamination research and development project authorized by Congress under the 1984 Energy and Water Development Appropriations Act. DOE placed responsibility for HISS under the Formerly Utilized Sites Remedial Action Program (FUSRAP), which was established to identify and decontaminate or otherwise control sites where residual radioactive materials remain from the early years of the nation's atomic energy program or from commercial operations causing conditions that Congress has authorized DOE to remedy. In 1992 there were no environmental occurrences or unplanned contaminant releases as defined in DOE requirements and in the Superfund Amendment and Reauthorization Act (SARA) Title III of CERCLA

  20. Anopheline Reproductive Biology: Impacts on Vectorial Capacity and Potential Avenues for Malaria Control.

    Mitchell, Sara N; Catteruccia, Flaminia

    2017-12-01

    Vectorial capacity is a mathematical approximation of the efficiency of vector-borne disease transmission, measured as the number of new infections disseminated per case per day by an insect vector. Multiple elements of mosquito biology govern their vectorial capacity, including survival, population densities, feeding preferences, and vector competence. Intriguingly, biological pathways essential to mosquito reproductive fitness directly or indirectly influence a number of these elements. Here, we explore this complex interaction, focusing on how the interplay between mating and blood feeding in female Anopheles not only shapes their reproductive success but also influences their ability to sustain Plasmodium parasite development. Central to malaria transmission, mosquito reproductive biology has recently become the focus of research strategies aimed at malaria control, and we discuss promising new methods based on the manipulation of key reproductive steps. In light of widespread resistance to all public health-approved insecticides targeting mosquito reproduction may prove crucial to the success of malaria-eradication campaigns. Copyright © 2017 Cold Spring Harbor Laboratory Press; all rights reserved.

  1. Integrating movement ecology with biodiversity research - exploring new avenues to address spatiotemporal biodiversity dynamics.

    Jeltsch, Florian; Bonte, Dries; Pe'er, Guy; Reineking, Björn; Leimgruber, Peter; Balkenhol, Niko; Schröder, Boris; Buchmann, Carsten M; Mueller, Thomas; Blaum, Niels; Zurell, Damaris; Böhning-Gaese, Katrin; Wiegand, Thorsten; Eccard, Jana A; Hofer, Heribert; Reeg, Jette; Eggers, Ute; Bauer, Silke

    2013-01-01

    Movement of organisms is one of the key mechanisms shaping biodiversity, e.g. the distribution of genes, individuals and species in space and time. Recent technological and conceptual advances have improved our ability to assess the causes and consequences of individual movement, and led to the emergence of the new field of 'movement ecology'. Here, we outline how movement ecology can contribute to the broad field of biodiversity research, i.e. the study of processes and patterns of life among and across different scales, from genes to ecosystems, and we propose a conceptual framework linking these hitherto largely separated fields of research. Our framework builds on the concept of movement ecology for individuals, and demonstrates its importance for linking individual organismal movement with biodiversity. First, organismal movements can provide 'mobile links' between habitats or ecosystems, thereby connecting resources, genes, and processes among otherwise separate locations. Understanding these mobile links and their impact on biodiversity will be facilitated by movement ecology, because mobile links can be created by different modes of movement (i.e., foraging, dispersal, migration) that relate to different spatiotemporal scales and have differential effects on biodiversity. Second, organismal movements can also mediate coexistence in communities, through 'equalizing' and 'stabilizing' mechanisms. This novel integrated framework provides a conceptual starting point for a better understanding of biodiversity dynamics in light of individual movement and space-use behavior across spatiotemporal scales. By illustrating this framework with examples, we argue that the integration of movement ecology and biodiversity research will also enhance our ability to conserve diversity at the genetic, species, and ecosystem levels.

  2. Contextual Influences on Evaluative Style and its Effectiveness: Three Avenues for Future Research

    J. Noeverman (Jan); B.A.S. Koene (Bas)

    2010-01-01

    textabstractMany accounting studies have investigated the effects of differences in evaluative style on subordinate managers’ attitudes and performance. These studies have usually based the distinction of different evaluative styles on the extent to which a superior uses and relies on accounting

  3. Non-Verbal Communication Training: An Avenue for University Professionalizing Programs?

    Gazaille, Mariane

    2011-01-01

    In accordance with today's workplace expectations, many university programs identify the ability to communicate as a crucial asset for future professionals. Yet, if the teaching of verbal communication is clearly identifiable in most university programs, the same cannot be said of non-verbal communication (NVC). Knowing the importance of the…

  4. Organic and Low-Input Dairy Farming: Avenues to Enhance Sustainability and Competitiveness in the EU

    Scollan, Nigel; Padel, Susanne; Halberg, Niels; Hermansen, J.E.; Nicholas, Pip; Rinne, Marketta; Zanoli, Raffaele; Zollitsch, Werner; Lauwers, Ludwig

    2017-01-01

    Whether farming strategies built on continuing input intensification or relying on integrated natural resource management are more sustainable and competitive is at the core of the agricultural development debate. The five-year (2011–16) Sustainable Organic and Low Input Dairying (SOLID) project, funded by the European Commission, involved 25 partners across 10 European countries and was designed to support innovation in European organic and low-input dairy farming. Results show that such sys...

  5. Structural Assessment of Knowledge and Skill

    1992-08-01

    Street San Diego, CA 92152-6800 Chicago, IL 60616 Dr. Menucha Birenbaum Educational Testing Serv. Library, Code 231 Dr. Lorraine 0. Eyde Princeton, NJ...University Dr. Norman Frederiksen Educational Testing Service Rosedale Road Department of Psychology Educational Testing Service Princeton, NJ 08541... Psychology Educational Testing Service Arlington, VA 22207 Carnegie-Mellon University Princeton, NJ 08541 5000 Forbes Avenue Dr. Delwyn Harnisch Pittsburgh

  6. Building America Case Study: Simplified Air Distribution, Desuperheaters, and Sub-Slab Geothermal Heat Exchangers, Pittsburgh, Pennsylvania

    N. Mittereder, A. Poerschke

    2017-05-01

    This report presents a cold-climate project that examines an alternative approach to ground source heat pump (GSHP) ground loop design. The innovative ground loop design is an attempt to reduce the installed cost of the ground loop heat exchange portion of the system by containing the entire ground loop within the excavated location beneath the basement slab.

  7. Building America Case Study: Simplified Air Distribution, Desuperheaters, and Sub-Slab Geothermal Heat Exchangers, Pittsburgh, Pennsylvania

    2017-06-08

    This report presents a cold-climate project that examines an alternative approach to ground source heat pump (GSHP) ground loop design. The innovative ground loop design is an attempt to reduce the installed cost of the ground loop heat exchange portion of the system by containing the entire ground loop within the excavated location beneath the basement slab.

  8. Environmental Assessment/Baseline Survey to Establish New Drop Zone (DZ) in Cadiz, Ohio, Pittsburgh Air Reserve Station, Coraopolis, Pennsylvania

    2009-03-01

    International Airport LATN Low Altitude Tactical Navigation MACA Military Airspace Collision Avoidance µg/m3 microgram per cubic meter MSL mean sea...Drop Zone in Cadiz, OH The 911 AW has a Military Airspace Collision Avoidance ( MACA ) plan that includes procedures for clearing local airspace prior...existing MACA plan to include activities at the new drop zone. The MACA includes placing a radio call into the local airport to clear local traffic

  9. EnviroAtlas - Pittsburgh, PA - Domestic Water Use per Day by U.S. Census Block Group

    U.S. Environmental Protection Agency — As included in this EnviroAtlas dataset, the community level domestic water use was calculated using locally available water use data per capita in gallons of water...

  10. 78 FR 73584 - CSX Transportation, Inc.-Corporate Family Merger Exemption-Buffalo, Rochester and Pittsburgh Company

    2013-12-06

    ... overhead costs, and that the transaction will reduce corporate overhead and duplication by eliminating one... jointly filed a verified notice of exemption under 49 CFR 1180.2(d)(3) for a corporate family transaction... Unclaimed Property. Under the proposed transaction, BR&P will be merged with and into CSXT. Applicants state...

  11. MRI-Guided High–Dose-Rate Intracavitary Brachytherapy for Treatment of Cervical Cancer: The University of Pittsburgh Experience

    Gill, Beant S.; Kim, Hayeon; Houser, Christopher J. [Department of Radiation Oncology, Magee-Womens Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (United States); Kelley, Joseph L.; Sukumvanich, Paniti; Edwards, Robert P.; Comerci, John T.; Olawaiye, Alexander B.; Huang, Marilyn; Courtney-Brooks, Madeleine [Department of Gynecologic Oncology, Magee-Womens Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (United States); Beriwal, Sushil, E-mail: beriwals@upmc.edu [Department of Radiation Oncology, Magee-Womens Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (United States)

    2015-03-01

    Purpose: Image-based brachytherapy is increasingly used for gynecologic malignancies. We report early outcomes of magnetic resonance imaging (MRI)-guided brachytherapy. Methods and Materials: Consecutive patient cases with FIGO stage IB1 to IVA cervical cancer treated at a single institution were retrospectively reviewed. All patients received concurrent cisplatin with external beam radiation therapy along with interdigitated high–dose-rate intracavitary brachytherapy. Computed tomography or MRI was completed after each application, the latter acquired for at least 1 fraction. High-risk clinical target volume (HRCTV) and organs at risk were identified by Groupe Européen de Curiethérapie and European SocieTy for Radiotherapy and Oncology guidelines. Doses were converted to equivalent 2-Gy doses (EQD{sub 2}) with planned HRCTV doses of 75 to 85 Gy. Results: From 2007 to 2013, 128 patients, median 52 years of age, were treated. Predominant characteristics included stage IIB disease (58.6%) with a median tumor size of 5 cm, squamous histology (82.8%), and no radiographic nodal involvement (53.1%). Most patients (67.2%) received intensity modulated radiation therapy (IMRT) at a median dose of 45 Gy, followed by a median brachytherapy dose of 27.5 Gy (range, 25-30 Gy) in 5 fractions. At a median follow up of 24.4 months (range, 2.1-77.2 months), estimated 2-year local control, disease-free survival, and cancer-specific survival rates were 91.6%, 81.8%, and 87.6%, respectively. Predictors of local failure included adenocarcinoma histology (P<.01) and clinical response at 3 months (P<.01). Among the adenocarcinoma subset, receiving HRCTV D{sub 90} EQD{sub 2} ≥84 Gy was associated with improved local control (2-year local control rate 100% vs 54.5%, P=.03). Grade 3 or greater gastrointestinal or genitourinary late toxicity occurred at a 2-year actuarial rate of 0.9%. Conclusions: This study constitutes one of the largest reported series of MRI-guided brachytherapy in North America, demonstrating excellent local control with acceptable morbidity. Dose escalation may be warranted when feasible for adenocarcinomas to offset the risk of local failure.

  12. Particle Physics at the University of Pittsburgh Summary Report for Proposal Period FY'09-11

    Boudreau, Joe [Univ. of Pittsburgh, PA (United States); Dytman, Steven [Univ. of Pittsburgh, PA (United States); Mueller, James [Univ. of Pittsburgh, PA (United States); Naples, Donna [Univ. of Pittsburgh, PA (United States); Paolone, Vittorio [Univ. of Pittsburgh, PA (United States); Savinov, Vladimir [Univ. of Pittsburgh, PA (United States)

    2012-10-01

    Presented is the final summary report for grant DOE-FG02-91ER40646. The HEP group at the University consists of three tasks: B,D and L. Task B supports Pitt's CDF group at the energy frontier which includes Joe Boudreau and Paul Shepard. Work of the group includes Hao Song's thesis on the measurement of the B_c lifetime using exclusive J/psi+pion decays, and an update of the previous B_c semi-leptonic analyses under the supervision of Paul Shepard. Task D supports Pitt's neutrino group at the intensity frontier which includes PIs Dytman, Naples and Paolone. The group also includes postdoctoral research associate Danko, and thesis students Isvan (MINOS), Eberly (Minerva ), Ren (Minerva )and Hansen (T2K). This report summarizes their progress on ongoing experiments which are designed to make significant contributions to a detailed understanding of the neutrino mixing matrix. Task L supports Pitt's ATLAS group at the energy frontier and includes investigators Vladimir Savinov, James Mueller and Joe Boudreau. This group contributed both to hardware (calorimeter electronics, Savinov) and to software (Simulation, Detector Description, and Visualization: Boudreau and Mueller; MC generators: Savinov) and a summary of their progress is presented.

  13. A Survey of the Freshwater Mussels of the Ohio River from Greenup Locks and Dam to Pittsburgh, Pennsylvania,

    1980-02-06

    1823) X x Lampsilis ovata* (Say, 1817) x x Lampsilis fasciola Raf., 1820 x Epioblasma triguetra (Raf., 1820) x __ TOTALS . . . . 38 29 35 41 Summation of...Lampsilis ovata* (Say, 1817) Lainpsilis fasciola * Raf., 1820 Epioblasma triguetra* (Raf., 1820) 42 Summary of River Faunal Changes Three species and

  14. Online Job Tutorials @ the Public Library: Best Practices from Carnegie Library of Pittsburgh's Job & Career Education Center

    Rhea M. Hebert

    2013-09-01

    Full Text Available This article describes the Job & Career Education Center (JCEC tutorial project completed in September of 2012. The article also addresses the website redesign implemented to highlight the tutorials and improve user engagement with JCEC online resources. Grant monies made it possible for a Digital Outreach Librarian to create a series of tutorials with the purpose of providing job-related assistance beyond the JCEC in the Carnegie Library of Pittsburgh—Main location. Benchmarking, planning, implementation, and assessment are addressed. A set of best practices for all libraries (public, academic, school, special are presented. Best practices are applicable to tutorials created with software other than Camtasia, the software used by the JCEC project.

  15. 75 FR 6635 - Foreign-Trade Zone 33-Pittsburgh, Pennsylvania, Expansion of Manufacturing Authority, Subzone 33E...

    2010-02-10

    ...-81u), and the regulations of the Board (15 CFR part 400). It was formally filed on February 4, 2010. Subzone 33E (123 employees, 360 million square meters coating capacity) currently has authority for the... the production of monochrome TTR printer rolls (some 336 million square meters capacity), using...

  16. Annual Conference on Magnetism and Magnetic Materials, 29th, Pittsburgh, PA, November 8-11, 1983, Proceedings

    Hasegawa, R.; Koon, N.C.; Cooper, B.R.

    1984-01-01

    Various topics on magnetism and magnetic materials are addressed. The subjects considered include: spin glasses, amorphous magnetism, actinide and rare earth intermetallics, magnetic excitation, itinerant magnetism and magnetic structure, valence instabilities, Kondo effect, transport and Hall effects, mixed valence and Kondo compounds, superconductivity and magnetism, d and f electron magnetism and superconductivity, Fe-based microcrystalline and permanent magnetic alloys, hard and soft magnetic materials, and magnetooptics. Also discussed are: numerical methods for magnetic field computation, recording theory and experiments, recording heads and media, magnetic studies via hyperfine interactions, magnetic semiconductors, magnet insulators, transition metal systems, random fields, critical phenomena and magnetoelastic effects and resonance, surfaces and interfaces, magnetostatic waves and resonance, bubble materials and implantation, bubble devices and physics, magnetic separation, ferrofluids, magnetochemistry, new techniques and materials, and new applications

  17. Unity and disunity in evolutionary sciences: process-based analogies open common research avenues for biology and linguistics.

    List, Johann-Mattis; Pathmanathan, Jananan Sylvestre; Lopez, Philippe; Bapteste, Eric

    2016-08-20

    For a long time biologists and linguists have been noticing surprising similarities between the evolution of life forms and languages. Most of the proposed analogies have been rejected. Some, however, have persisted, and some even turned out to be fruitful, inspiring the transfer of methods and models between biology and linguistics up to today. Most proposed analogies were based on a comparison of the research objects rather than the processes that shaped their evolution. Focusing on process-based analogies, however, has the advantage of minimizing the risk of overstating similarities, while at the same time reflecting the common strategy to use processes to explain the evolution of complexity in both fields. We compared important evolutionary processes in biology and linguistics and identified processes specific to only one of the two disciplines as well as processes which seem to be analogous, potentially reflecting core evolutionary processes. These new process-based analogies support novel methodological transfer, expanding the application range of biological methods to the field of historical linguistics. We illustrate this by showing (i) how methods dealing with incomplete lineage sorting offer an introgression-free framework to analyze highly mosaic word distributions across languages; (ii) how sequence similarity networks can be used to identify composite and borrowed words across different languages; (iii) how research on partial homology can inspire new methods and models in both fields; and (iv) how constructive neutral evolution provides an original framework for analyzing convergent evolution in languages resulting from common descent (Sapir's drift). Apart from new analogies between evolutionary processes, we also identified processes which are specific to either biology or linguistics. This shows that general evolution cannot be studied from within one discipline alone. In order to get a full picture of evolution, biologists and linguists need to complement their studies, trying to identify cross-disciplinary and discipline-specific evolutionary processes. The fact that we found many process-based analogies favoring transfer from biology to linguistics further shows that certain biological methods and models have a broader scope than previously recognized. This opens fruitful paths for collaboration between the two disciplines. This article was reviewed by W. Ford Doolittle and Eugene V. Koonin.

  18. Exploring avenues for best use of cytotechnologists in non-gynaecological cytology: Double screening or independent sign-out.

    Fischer, G; Haddad, M; Cormier, K

    2018-02-01

    Cytotechnologist (CT) screening workload has been decreasing due to the falling number of Papanicolaou tests. This continuing trend has prompted exploration of ways to best employ the CT skillset. One potential way of more effective use is by having two CTs double screen non-gynaecological (NGC) cases to assess whether this improves screening quality and concordance with pathologists. Another is evaluating the CT's performance on low-complexity negative NGC cases for a potential independent CT sign-out without pathologist review. In total, 1119 NGC cases were reviewed; 577 screened by two CTs and 542 screened by one CT. All cases were signed out by a pathologist and all CT interpretations were compared to the pathologist final diagnoses. The disagreements were classified based on degree of discrepancy. The extra workload by adding the second screener was assessed. The agreement rate between the CT's screening interpretation and pathologist's interpretation did not improve by adding a second CT compared to a single screener (91.5% vs 92.9%, respectively). CT to pathologist concordance was very high on low complexity NGC cases (voided urine, fluid, sputum) whether screened and interpreted as negative by one CT (97.3%) or two CTs (99.3%). Double screening of NGC cases by two cytotechnologists prior to pathologist sign-out does not improve screening quality and is not cost-effective. The high concordance between the CTs and pathologists in this limited group of low complexity negative cases suggests that such cases could be signed out independently by cytotechnologists. © 2017 John Wiley & Sons Ltd.

  19. The common marmoset monkey: avenues for exploring the prenatal, placental, and postnatal mechanisms in developmental programming of pediatric obesity.

    Riesche, Laren; Tardif, Suzette D; Ross, Corinna N; deMartelly, Victoria A; Ziegler, Toni; Rutherford, Julienne N

    2018-05-01

    Animal models have been critical in building evidence that the prenatal experience and intrauterine environment are capable of exerting profound and permanent effects on metabolic health through developmental programming of obesity. However, despite physiological and evolutionary similarities, nonhuman primate models are relatively rare. The common marmoset monkey ( Callithrix jacchus) is a New World monkey that has been used as a biomedical model for well more than 50 years and has recently been framed as an appropriate model for exploring early-life impacts on later health and disease. The spontaneous, multifactorial, and early-life development of obesity in the common marmoset make it a valuable research model for advancing our knowledge about the role of the prenatal and placental mechanisms involved in developmental programming of obesity. This paper provides a brief overview of obesity in the common marmoset, followed by a discussion of marmoset reproduction and placental characteristics. We then discuss the occurrence and utility of variable intrauterine environments in developmental programming in marmosets. Evidence of developmental programming of obesity will be given, and finally, we put forward future directions and innovations for including the placenta in developmental programming of obesity in the common marmoset.

  20. Radiological assessment report for the University of Rochester Annex, 400 Elmwood Avenue, Rochester, New York, April-May 1984

    Wynveen, R.A.; Smith, W.H.; Sholeen, C.M.; Flynn, K.F.

    1984-12-01

    In light of the results of the comprehensive radiological assessment of the annex and auxiliary facilities, the following conclusions can be made: There is no immediate hazard from the elevated levels of radioactivity detected; however, some of these levels are above criteria. The radon, thoron, actinon, long-lived particulates, and tritium in the air are all below criteria for unrestricted use. Some ductwork has been identified as being contaminated. All ductwork must, therefore, be considered potentially contaminated. Since several floor drains were found to exhibit elevated readings, and the samples had elevated concentrations of radionuclides, it must be concluded that the drain and sewer systems of the Annex are contaminated with radioactive material. Since the samples collected from the storm and sewer systems outside the building also had elevated concentrations of radionuclides, these systems are also considered contaminated with radioactive material. The grounds around the Annex have exhibited background concentrations of radionuclides. Two rooms, B-330 and B-332, were inaccessible for survey due to the presence of stored furniture and equipment. Therefore, no comment about their radiological status can be made. At the common baseboard for Room C-12 and C-16 and on the floor below the tile in Room C-40, contamination appeared to be masked by construction modifications. Other areas of the Annex must also be considered potentially contaminated where modifications may have masked the contamination