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Sample records for seven-year panel study

  1. THE EVALUATION OF FREQUENCY AND SEASONAL VARIATIONS OF ACID PEPTIC DISEASE: A SEVEN YEARS STUDY

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    Syed Iftikhar Haider

    2016-06-01

    Full Text Available Acid peptic disease (APD is a worldwide health problem. It includes a variety of inflammatory and ulcerative lesions involving esophagus, stomach and duodenum. The disease condition may persist with multiple symptoms, one of them being dyspepsia. The object of the present study was to determine the frequency and seasonal variations of APD in patients presenting with dyspeptic symptoms. This observational study was carried out at the endoscopy unit in Baqai Medical University from December 2003 to December 2010, over a period of seven years. The evolution of APD frequency remained equivocal throughout the study period. However, a decline was noted in the frequency of peptic ulcer disease (PUD especially for gastric and duodenal ulcer cases but a rise during autumn and winter seasons was also noted in duodenal ulcer cases.

  2. Work, diabetes and obesity: a seven year follow-up study among Danish health care workers.

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    Poulsen, Kjeld; Cleal, Bryan; Clausen, Thomas; Andersen, Lars L

    2014-01-01

    The rise in prevalence of diabetes is alarming and research ascribes most of the increase to lifestyle. However, little knowledge exists about the influence of occupational factors on the risk for developing diabetes. This study estimates the importance of work and lifestyle as risk factors for developing diabetes mellitus among healthcare workers and explores the association of work factors and obesity, which is a risk factor for diabetes. Questionnaire-based prospective cohort study among 7,305 health care workers followed for seven years in the Danish National Diabetes Register. We used bivariate comparisons to give an unadjusted estimate of associations, followed by adjusted survival analysis and logistic regression models to estimate the influences of potential risk factors related to job, health and lifestyle on diabetes and obesity. During seven years of follow up, 3.5% of participants developed diabetes, associated with obesity (HR  =  6.53; 95% CI 4.68-9.10), overweight (HR  =  2.89; CI 2.11-3.96) age 50-69 y (HR  =  2.27; 95% CI 1.57-3.43) and high quality of leadership (HR  =  1.60; CI 1.19-2.16). Obesity at baseline was most common among the youngest employees, and was mainly associated with developing diabetes (OR  =  3.84; CI 2.85-5.17), impaired physical capacity and physical inactivity. In the occupational setting, obesity was associated with shift work, severe musculoskeletal pain, low influence, but also by good management, fewer role conflicts and a positive work-life balance. Looking only at non-smokers, removed the influence of age and pain. However, non-smokers also had higher depression scores and more role conflicts. Confirming obesity as the strongest risk factor for developing diabetes, the present study identified few occupational risk factors. However, obesity, the key risk factor for diabetes, had a more variable relation with work than did diabetes.

  3. Work, diabetes and obesity: a seven year follow-up study among Danish health care workers.

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    Kjeld Poulsen

    Full Text Available The rise in prevalence of diabetes is alarming and research ascribes most of the increase to lifestyle. However, little knowledge exists about the influence of occupational factors on the risk for developing diabetes. This study estimates the importance of work and lifestyle as risk factors for developing diabetes mellitus among healthcare workers and explores the association of work factors and obesity, which is a risk factor for diabetes.Questionnaire-based prospective cohort study among 7,305 health care workers followed for seven years in the Danish National Diabetes Register. We used bivariate comparisons to give an unadjusted estimate of associations, followed by adjusted survival analysis and logistic regression models to estimate the influences of potential risk factors related to job, health and lifestyle on diabetes and obesity.During seven years of follow up, 3.5% of participants developed diabetes, associated with obesity (HR  =  6.53; 95% CI 4.68-9.10, overweight (HR  =  2.89; CI 2.11-3.96 age 50-69 y (HR  =  2.27; 95% CI 1.57-3.43 and high quality of leadership (HR  =  1.60; CI 1.19-2.16. Obesity at baseline was most common among the youngest employees, and was mainly associated with developing diabetes (OR  =  3.84; CI 2.85-5.17, impaired physical capacity and physical inactivity. In the occupational setting, obesity was associated with shift work, severe musculoskeletal pain, low influence, but also by good management, fewer role conflicts and a positive work-life balance. Looking only at non-smokers, removed the influence of age and pain. However, non-smokers also had higher depression scores and more role conflicts.Confirming obesity as the strongest risk factor for developing diabetes, the present study identified few occupational risk factors. However, obesity, the key risk factor for diabetes, had a more variable relation with work than did diabetes.

  4. Health-related quality of life after vertebral or hip fracture: a seven-year follow-up study

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    Toss Göran

    2009-11-01

    Full Text Available Abstract Background The negative impact of vertebral and hip low-energy fractures on health-related quality-of-life (HRQOL has been demonstrated previously, but few prospective long-term follow-up studies have been conducted. This study aims to (i investigate the changes and long-term impact of vertebral or hip fracture and between fracture groups on HRQOL in postmenopausal women prospectively between two and seven years after the inclusion fracture, (ii compare HRQOL results between fracture and reference groups and (iii study the relationship between HRQOL and physical performance, spinal deformity index and bone mineral density at seven-year follow-up. Methods Ninety-one women examined two years after a low-energy vertebral or hip fracture were invited to a new examination seven years after the diagnosis. HRQOL was examined using the SF-36 questionnaire and was compared with an age and sex-matched reference group. Physical function was assessed using tests and questionnaires. Bone mineral density was measured. Radiographs of the spine were evaluated using the visual semiquantitative technique. A longitudinal and cross-sectional design was used in this study. Statistical analyses included descriptive statistics, Student's t-tests, ANCOVA, and partial correlation. Results Sixty-seven women participated. In the 42 women (mean age 75.8, SD 4.7 with vertebral fracture as inclusion fracture, bodily pain had deteriorated between two and seven years and might be explained by new fracture. Remaining pronounced reduction of HRQOL was seen in all domains except general health and mental health at seven-year follow-up in women with vertebral fractures compared to the reference group (p Conclusion The long-term reduction of HRQOL in women with vertebral fracture emerged clearly in this study. The relationships between HRQOL and physical performance in women with vertebral and hip fracture raise questions for more research.

  5. Seven-year retrospective clinical study evaluating efficacy of stainless steel mesh in mandibular fractures.

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    Chakraborty, Sudip; Ghosh, Samiran; Burman, Richi; Ray, Amit

    2011-10-01

    The use of titanium mesh in communited mandibular fractures has been substantially documented. However, the use of stainless steel mesh for routine fixation in mandibular fractures has not been widely reported. The aim of the present study was to evaluate the efficacy of stainless steel mesh for routine osteosynthesis of mandibular fractures. A total of 252 patients who had been diagnosed with 287 single or multiple mandibular fractures at Guru Nanak Institute of Dental Science and Research from 2002 to 2009 were selected for the present study. Those with condylar fractures and other maxillofacial injuries were excluded from the study. The patients were evaluated preoperatively, intraoperatively, and postoperatively at 1 day, 6 weeks, and 3 and 6 months. The local complications, occlusion (for static function), and chewing (for dynamic function) were evaluated postoperatively. The intraoperative time taken for implant fixation (from site exposure to fixation of the last screw) was 32 minutes. Of the 252 patients, 40 (15.8%) had local complications and 24 patients required implant removal. Of the 252 patients, 82% had bilaterally satisfactory occlusion according to the surgeon at 6 months postoperatively. Discomfort in chewing unilaterally or bilaterally was reported by 17% of the patients. The results of our study have shown that stainless steel mesh has acceptable complication rates and the ability to maintain occlusion and chewing postoperatively compared with the present standards of care of mandibular fractures using miniplates. The lower cost and versatile placement of screws were the principal advantages. However, placement near the mental foramen with an extraoral approach for certain sites is the primary disadvantage. Copyright © 2011 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  6. Increase of mild disability in Japanese elders: A seven year follow-up cohort study

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    Okochi Jiro

    2005-05-01

    Full Text Available Abstract Background Japan has the highest life expectancy in the world. In a 2002 census government report, 18.5% of Japanese were 65 years old and over and 7.9% were over 75 years old. In this ageing population, the increase in the number of dependent older persons, especially those with mild levels of disability, has had a significant impact on the insurance budget. This study examines the increase of mild disability and its related factors. Methods All community-dwelling residents aged 65 and over and without functional decline (n = 1560, of Omishima town, Japan, were assessed in 1996 using a simple illustrative measure, "the Typology of the Aged with Illustrations" to establish a baseline level of function and were followed annually until 2002. The prevalence and incidence of low to severe disability, and their association with chronic conditions present at the commencement of the study, was analyzed. A polychotomous logistic regression model was constructed to estimate the association of each chronic condition with two levels of disability. Results An increase in mild functional decline was more prevalent than severe functional decline. The accumulation of mild disability was more prominent in women. The major chronic conditions associated with mild disability were chronic arthritis and diabetes in women, and cerebrovascular accident and malignancy in men. Conclusion This study showed a tendency for mild disability prevalence to increase in Japanese elders, and some risk factors were identified. As mild disability increasingly prevalent, these findings will help determine priorities for its prevention in Japanese elders.

  7. [Conduct disorders in seven-year-old children--results of ELSPAC study. 2. Risk factors].

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    Kukla, L; Hrubá, D; Tyrlík, M; Matejová, H

    2008-01-01

    Conduct disorders related to hyperactivity and significant attention deficit are caused by several types of risk factors-genetic, biological, environmental and psychosocial. A cohort of children was followed longitudinally in a prospective study during the pregnancy and childhood (ELSPAC). In the age of 7 years, marked behavioural divergences were described in 4,4% of children by their attending physicians. These children were also more often afflicted by other pathological symptoms (hyperactivity, sleep and psychomotor disorders). From the data collected from parents and physicians in the previous phases of investigation we selected possible risk factors which affect the prenatal and postnatal periods: prenatal exposure of children to smoking, alcohol, chemical substances, prenatal development complications, the level of education of parents, family dysfunction, alcoholism of both parents, conflicts with the police, mother's disturbed mental health. In the sample of 3752 children from the city of Brno, no behavioural divergence was found in 96.5% of cases. The presence of one or two of the four observed divergences occurred in 3.2% and 3 to 4 conduct disorder symptoms occurred in 0.3% children, significantly more often in boys. The children with conduct disorders compared to the children with no symptoms had significantly lower average birthweight, lower head circumference, their mothers had more often lower education, smoked and had psychological problems in childhood and as adults and the fathers had more often conflicts with the law. The ELSPAC study did not have the methodological possibility of studying the genetic-environmental interactions; nevertheless it contributes to the evidence supporting that some factors can negatively effect the foetal development and the unfavourable family environment can participate in the development of conduct disorders which can progress during lifetime.

  8. Mandibular Overdentures Retained by Two Mini-Implants: A Seven-Year Retention and Satisfaction Study.

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    Catalán, Alfonso; Martínez, Alejandra; Marchesani, Francisco; González, Urcesino

    2016-07-01

    Patients with atrophic edentulous ridges generally have problems with retention, therapeutic satisfaction, and comfort with their complete dentures. An alternative treatment to assist in improving retention and stability involves the use of mini-implants. The aim of this study was to evaluate the retention of mandibular overdentures connected to two mini-implants and overall patient satisfaction with them. Seven patients with atrophic mandibular ridges (Type 4D Misch classification), aged 62 to 74 years old were rehabilitated with complete dentures. In each patient, two mini-implants measuring 15 or 13 mm in length and 1.8 mm in diameter were placed. After 15 days, overdentures were connected to the mini-implants with O-ring attachments. In each patient, retention of the overdentures was measured, and a survey of therapeutic satisfaction before and after connection to the mini-implants was administered. Prosthesis retention was measured with a digital dynamometer at 1 month, 6 months, and 2, 3, 5, and 7 years after mini-implant placement. Patient satisfaction was assessed with a survey. Data were analyzed with Student's t-test (satisfaction survey) and the Friedman test (retention measurements and satisfaction survey). The initial retention values (0.34 to 0.63 N without mini-implants) varied significantly (p ≤ 0.050). These values were less than the subsequent measurements of 3.92 to 9.64 N, taken after placement of the mini-implants and connecting them to the dentures. Satisfaction was good to very good over the 7-year observation period. Mucosa and peri-implant bone showed no pathological changes. In this limited sample size clinical study the results indicated that after connecting mandibular overdentures to two mini-implants, patient satisfaction significantly increased and retention significantly improved during the 7-year observation period. © 2015 by the American College of Prosthodontists.

  9. Seven years of teenage pregnancy in an inner London genitourinary medicine service - a retrospective cohort study.

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    Hegazi, Aseel; Daley, Natalie; Williams, Elizabeth; McLeod, Felicity; Rafiezadeh, Saba; Prime, Katia

    2014-12-01

    Young people attending genitourinary medicine services are at high risk of unplanned pregnancy. We performed a retrospective cohort study to identify characteristics of pregnant teenagers accessing an inner London genitourinary medicine service. There were 481 pregnancies in 458 teenagers with 54 previous pregnancies and 46 previous terminations of pregnancy. The under-18 and under-16 teenage pregnancy rates were 92.1 and 85.8 per 1000 age-matched clinic attendees, respectively. Median age was 17.1 years. 'Black Other' teenagers ('Black British', 'Mixed White-Black Caribbean' and 'Mixed White-Black African') were over-represented, compared to our clinic population, while those of White ethnicity were under-represented. Few pregnancies (1.5%) were planned with the majority (64%) intending terminations of pregnancy. Most teenagers did not use consistent contraception. Two-thirds of patients had attended genitourinary medicine services in the past and sexually transmitted infection prevalence at presentation was high. Effectively targeting the sexual and reproductive health needs of teenage genitourinary medicine clinic attendees may have a significant impact on reducing sexually transmitted infections, unplanned pregnancy and terminations of pregnancy in this group. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  10. [Conduct disorders in seven-year-old children--results of ELSPAC study 1. Co-morbidity].

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    Kukla, L; Hrubá, D; Tyrlík, M; Matejová, H

    2008-01-01

    The interest of experts in conduct disorders (CD) research is growing during the last two decades. The research areas include the diagnostics, ethiopathogenesis and treatment and also the comorbidity, especially with the hyperkinetic syndrome incidence (Attention Deficit Hyperactivity Disorder--ADHD). This paper intends to describe the conduct disorder occurrence and its other manifestations of divergence found during the investigation of children followed in the prospective longitudinal study ELSPAC in seven, respectively eight years of their age. Data of 6100 seven-year-old children characterizing their behaviour was collected from mothers and attending physicians. In the school year during which this investigation phase took place 2518 of the children reached eight years of age and their behaviour, temperament and school results were also evaluated by their teachers. The children were divided into three groups according to the presence or absence of the symptoms, which characterize conduct disorders (found by physicians): "stubborn negativistic behaviour", "inability to pay attention", "aggressiveness" and "inadequacy of reactions". The presence of two of these symptoms was found in 3%, presence of all four symptoms in additional 1.4% of children. Parents and teachers more often indicated various symptoms of hyperactivity in children with conduct disorders. In almost 5% of the ELSPAC cohort children in seven years of their age those symptoms were diagnosed, which match the Conduct Disorder criteria and Attention Deficit Hyperactivity Disorder (ADHD) criteria. In agreement with similar studies these frequent comorbidities were found: sleep disorders, psychomotor development disorders and laterality changes. The cognitive abilities evaluated by mothers and also teachers based on schoolwork results were more often worsened in children with conduct disorders. Various data indicating their worse social adaptability (which significantly disturbed the class) occurred

  11. Trends in condom use and risk behaviours after sexual exposure to HIV: a seven-year observational study.

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    Enrique Casalino

    Full Text Available OBJECTIVE: We aimed to determine the trends in numbers and percentages of sexually exposed persons to HIV (SE consulting an ED for post-exposure prophylaxis (PEP, as well as predictors of condom use. STUDY DESIGN: We conducted a prospective-observational study. METHODS: We included all SE attendances in our Emergency Department (ED during a seven-year study-period (2006-2012. Trends were analyzed using time-series analysis. Logistic Regression was used to define indicators of condom use. RESULTS: We enrolled 1851 SE: 45.7% reported intercourse without condom-use and 12.2% with an HIV-infected partner. Significant (p0.05, in MSM +228% (p<0.001 and +49% (p<0.001, in Heterosexuals +68% (p<0.001 and +10% (p = 0.08. Among MSM, significant rising trends were found in those reporting high-risk behaviours: anal receptive (+450% and +76% and anal insertive (+l33% and +70% intercourses. In a multivariate logistic regression analysis, heterosexuals, vaginal intercourse, visit during the night-shift and short time delay between SE and ED visit, were significantly associated with condom-use. CONCLUSION: We report an increasing trend in the number of SE, mainly among MSM, and rising trends in high-risk behaviours and unprotected sexual intercourses among MSM. Our results indicate that SE should be considered as a high-risk population for HIV and sexually transmitted diseases.

  12. Health locus of control in patients undergoing coronary artery surgery - changes and associated outcomes: a seven-year cohort study.

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    Rideout, Andrew; Tolmie, Elizabeth; Lindsay, Grace

    2017-01-01

    Health locus of control is a measure of an individual's beliefs in factors that are thought to determine health experiences. Scores are generated and form a graduated linear scale from external to internal control, with respect to their views on health causality. Health locus of control has been considered to be a relatively stable entity. However, it is not clear if this status changes in the advent of serious health challenges, such as coronary artery bypass graft surgery. The aim of this study is to explore the variability of health locus of control and its association with postoperative health in this context. In a longitudinal cohort study of patients undergoing coronary artery bypass graft surgery, a purposive sample ( n=215) were recruited from the waiting list and followed up postoperatively, at approximately one year and seven years later. Patients undergoing coronary artery bypass graft surgery demonstrated marked fluctuations in health locus of control in their peri-operative and rehabilitative phases. Mean health locus of control became more external (often associated with poorer outcomes) peri-operatively, and more internal (generally associated with better health outcomes) in the rehabilitative period. Health locus of control scores were shown to be changeable during a major health care intervention, with possible consequences for patient outcomes and care needs. The significant health belief upheaval demonstrated in this cohort should be considered in assessing patients preoperatively, and managed as part of the patients' clinical journey by both acute and rehabilitation staff. It is likely to have particular importance in individualised assessment and management of future prevention advice for patients.

  13. An outcome study of chronic patellofemoral pain syndrome. Seven-year follow-up of patients in a randomized, controlled trial.

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    Kannus, P; Natri, A; Paakkala, T; Järvinen, M

    1999-03-01

    We determined prospectively the long-term outcomes of nonoperative treatment of chronic patellofemoral pain syndrome. Of forty-nine patients in a prospective, randomized, double-blind study of unilateral chronic patellofemoral pain syndrome in the knee, forty-five were reexamined seven years after the initial trial of treatment. In the earlier trial, the short-term (six-month) effects of intra-articular injections of glycosaminoglycan polysulfate combined with intensive quadriceps-muscle exercises were compared with those of injections of a placebo combined with exercises and with those of exercises alone. At seven years, the follow-up consisted of standardized subjective, functional, and clinical assessments and muscle-strength measurements as well as magnetic resonance imaging, radiography, and bone-densitometry measurements of the knee. At six months, complete subjective, functional, and clinical recovery had occurred in almost three-fourths of the patients and, with the numbers available for study, neither significant nor clinically important differences among the three initial treatment groups were detected. The subjective and functional parameters showed few changes between six months and seven years; almost three-fourths of the patients still had full subjective and functional recovery at the time of the latest follow-up. However, according to the physician's clinical evaluation, the number of patients who had no symptoms on the patellar compression and apprehension tests decreased over time, from forty-two (93 percent) and forty (89 percent) of forty-five patients at six months to thirty (67 percent) and thirty-one (69 percent) at seven years; these changes were significant (p = 0.002 and p = 0.023, respectively). The number of patients who had crepitation on the patellar compression test increased over time, from twenty-six (58 percent) at six months to thirty-six (80 percent) at seven years (p = 0.021). The physician's overall assessment showed a similar

  14. The Acquisition of the English Progressive: A Case Study of a Seven-Year-Old Hebrew Speaker. Working Papers on Bilingualism, No. 18.

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    Olshtain, Elite

    The present paper reports on a case study investigating the acquisition of form and function of the English progressive by a seven-year-old Hebrew speaker, learning English as a second language. The paper describes the different elicitation techniques used, and discusses the suitability of such techniques for the investigation of form and…

  15. A long-term evaluation of alternative treatments to replacement of resin-based composite restorations: results of a seven-year study.

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    Gordan, Valeria V; Garvan, Cynthia W; Blaser, Paul K; Mondragon, Eduardo; Mjör, Ivar A

    2009-12-01

    In a seven-year prospective cohort study, the authors assessed the longevity of defective resin-based composite (RBC) restorations that were not treated or were treated by means of repair, sealing, refinishing or total replacement. They also aimed to identify and quantify the main reasons clinicians diagnosed restorations as defective. Thirty-seven patients--19 women and 18 men--who were aged 27 through 78 years (mean = 57 years, standard deviation [SD] = 13 years) and had a total of 88 defective restorations participated in the study. Two of the authors assigned each restoration to one of five treatment groups, depending on the patient's treatment need: repair (n = 25), sealing of defective margins (n = 12), refinishing (n = 19), replacement (n = 16) and no treatment (n = 16). The authors conducted a survival analysis (according to modified U.S. Public Health Service criteria) at baseline and again at six months, one year, two years and seven years after treatment. The authors determined that the main reasons clinicians diagnosed the 88 restorations as being defective were marginal discoloration (n = 53, 60.2 percent), marginal degradation (n = 18, 20.5 percent) and color mismatch (n = 17, 19.3 percent). The authors examined 69 (78 percent) restorations at six months, 68 (77 percent) after one year, 62 (70 percent) after two years and 53 after seven years (60 percent). The percentages of failed restorations for each treatment after seven years were 0 percent for repair, 0 percent for sealing of defective margins, 18 percent for refinishing, 21 percent for replacement and 23 percent for no treatment. The P value for the log-rank test of equality for these groups was .36. Restorations degraded to varying degrees in all criteria, and the survival of restorations differed among treatment approaches. Longitudinal data collected across seven years support the viability of all nonreplacement restoration treatment strategies.

  16. A seven-year study on head injury in infants, Iran —— the changing pattern

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    Fakharian Esmaeil

    2014-06-01

    Full Text Available Objective: Head injury (HI is the leading cause of mortality and life-long disability in infants. Infants have different anatomical and pathophysiological brain structures from other age groups. The aim of this study was to survey infant HI patients admitted to Shahid Behest Hospital in Kashan, Iran from 2004 to 2010, and to identify the causes of HIs in this age group. Methods: In this retrospective study, all HI patients under the age of two who were hospitalized for more than 24 hours between January 2004 and January 2010 were enrolled in the study. Demographic, etiologic, and injury data were collected and a descriptive analysis was performed. Results: Infants comprised 20.8% of all children (under 15 years old with HIs and 65.1% of the injuries occurred in the home. Falls were the most common cause of injury (63.4%. In hospital mortality was 6.6 per 100 000 infants. A decreasing trend was seen in home events, but HIs caused by traffic accidents were increasing during the study period. The amount of HI infants resulting from car accidents has tripled from the years 2004 to 2010. Conclusion: Although home events and falling are the main causes of infant HIs and need attention, our study showed an increase of HIs caused by road traffic accidents, especially by car accidents, thus legislation for the implementation of protective equipment such as child safety seats and programs is urgently needed. Key words: Infant; Brain injuries; Epidemiology

  17. Stereotactic Body Radiotherapy as Treatment for Organ Confined Low and Intermediate Risk Prostate Carcinoma, a Seven Year Study

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    Alan Jay Katz

    2014-09-01

    Full Text Available Objectives: Stereotactic body radiation therapy (SBRT takes advantage of the prostate’s low α/β ratio to deliver a large radiation dose in few fractions. Initial studies on small groups of low-risk patients support SBRT’s potential for clinical efficacy while limiting treatment-related morbidity and maintained quality of life (QOL. This prospective study expands upon prior studies to further evaluate SBRT efficacy for a large patient population with organ confined, low- and intermediate-risk prostate cancer patients. Methods: 477 patients with prostate cancer received CyberKnife SBRT. The median age was 68.6 years and the median PSA was 5.3 ng/ml. 324 patients were low-risk (PSA 10, or Gleason 3+4 with PSA <10; n=106 had a significantly higher bDFS than patients with high intermediate-risk (Gleason 3+4 with PSA 10-20 or Gleason 4+3; n=47, with bDFS of 93.5% versus 79.3%, respectively. For the low and low intermediate-risk groups, there was no difference in median PSA nadir or biochemical disease control between doses of 35 and 36.25 Gy. Conclusions: CyberKnife SBRT produces excellent biochemical control rates. Median PSA levels compare f

  18. Do burnout and work engagement predict depressive symptoms and life satisfaction? A three-wave seven-year prospective study.

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    Hakanen, Jari J; Schaufeli, Wilmar B

    2012-12-10

    Burnout and work engagement have been viewed as opposite, yet distinct states of employee well-being. We investigated whether work-related indicators of well-being (i.e. burnout and work engagement) spill-over and generalize to context-free well-being (i.e. depressive symptoms and life satisfaction). More specifically, we examined the causal direction: does burnout/work engagement lead to depressive symptoms/life satisfaction, or the other way around? Three surveys were conducted. In 2003, 71% of all Finnish dentists were surveyed (n=3255), and the response rate of the 3-year follow-up was 84% (n=2555). The second follow-up was conducted four years later with a response rate of 86% (n=1964). Structural equation modeling was used to investigate the cross-lagged associations between the study variables across time. Burnout predicted depressive symptoms and life dissatisfaction from T1 to T2 and from T2 to T3. Conversely, work engagement had a negative effect on depressive symptoms and a positive effect on life satisfaction, both from T1 to T2 and from T2 to T3, even after adjusting for the impact of burnout at every occasion. The study was conducted among one occupational group, which limits its generalizability. Work-related well-being predicts general wellbeing in the long-term. For example, burnout predicts depressive symptoms and not vice versa. In addition, burnout and work engagement are not direct opposites. Instead, both have unique, incremental impacts on life satisfaction and depressive symptoms. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. Quality of Life and Toxicity after SBRT for Organ-Confined Prostate Cancer, a Seven Year Study

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    Alan Jay Katz

    2014-10-01

    Full Text Available Objectives: Stereotactic body radiation therapy (SBRT yields excellent disease control for lowandintermediate-risk prostate cancer by delivering high doses of radiation in a small number offractions. Our report presents a 7-year update on treatment toxicity and quality of life (QOLfrom 515 patients treated with prostate SBRT.Methods: From 2006 to 2009, 515 patients with clinically localized, low-, intermediate- andhigh-risk prostate cancer were treated with SBRT using Cyberknife technology. Treatmentconsisted of 35 to 36.25 Gy in 5 fractions. Seventy-two patients received hormone therapy.Toxicity was assessed at each follow up visit using the Expanded Prostate Cancer IndexComposite (EPIC questionnaire and the Radiation Therapy Oncology Group (RTOG urinaryand rectal toxicity scale.Results: Median follow up was 72 months. The actuarial 7-year freedom from biochemicalfailure was 95.8%, 89.3% and 68.5% for low-, intermediate- and high-risk groups, respectively(p < 0.001. No patients experienced acute Grade III or IV acute complications. Fewer than 5%of patients had any acute Grade II urinary or rectal toxicity. Late toxicity was low, with Grade IIrectal and urinary toxicity of 4% and 9.1%, respectively, and Grade III urinary toxicity of 1.7%.Mean EPIC urinary and bowel QOL declined at 1 month post-treatment, returned to baseline by2 years and remained stable thereafter. EPIC sexual QOL declined by 23% at 6-12 months andremained stable afterwards. Of patients potent at baseline evaluation, 67% remained potent atlast follow-up.Conclusions: This study suggests that SBRT, when administered to doses of 35 to 36.25 Gy, isefficacious and safe. With long-term follow up in our large patient cohort, we continue to findlow rates of late toxicity and excellent rates of biochemical control.

  20. Description of a seven-year prospective study of human papillomavirus infection and cervical neoplasia among 10000 women in Guanacaste, Costa Rica,.

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    Bratti, M Concepción; Rodríguez, Ana C; Schiffman, Mark; Hildesheim, Allan; Morales, Jorge; Alfaro, Mario; Guillén, Diego; Hutchinson, Martha; Sherman, Mark E; Eklund, Claire; Schussler, John; Buckland, Julie; Morera, Lidia A; Cárdenas, Fernando; Barrantes, Manuel; Pérez, Elmer; Cox, Thomas J; Burk, Robert D; Herrero, Rolando

    2004-02-01

    The Guanacaste study ("Guanacaste Project," or GP), was designed to investigate the role of human papillomavirus (HPV) infection and its cofactors in the development of cervical neoplasia and to evaluate new cervical cancer screening technologies. The follow-up phase of the GP was designed to study why a small proportion of women infected with HPV develop cervical intraepithelial neoplasia grade 2 (CIN 2), CIN 3, or cancer (these three together are globally referred to as > or = CIN 2, that is, CIN 2 or worse). The purpose of this article is to describe this prospective study in detail and to present the preliminary findings regarding the incidence of cervical neoplasia. A cohort of 10 049 randomly selected women from 18 to 97 years old from Guanacaste, a province in northwestern Costa Rica, was intensively screened in 1993-1994 and then followed up for seven years after being enrolled. A questionnaire for demographic and risk factors was administered, and a pelvic examination was performed on sexually active women at each follow-up visit in order to obtain samples for screening tests and for research purposes. The final diagnosis given at the end of the enrollment phase categorized women into several groups according to the perceived risk of their developing either high-grade precursors of cancer or cancer. These groups were followed up at different intervals according to the risk of developing > or = CIN 2. The most active follow-up (every 6-12 months) was concentrated on the women most likely to develop >or = CIN 2, based on cytology (n = 492). The remainder of the cohort was followed either annually (n = 2 574) or after five to seven years of passive follow-up (n = 3 926). All women with possibly severe lesions detected by any technique were referred to colposcopy for further evaluation and treatment, and they were also censored from the study. Lesions >or = CIN 2 served as both the censoring outcome and our surrogate for cancer risk. Participation during

  1. Major depressive disorder seven years after the conflict in northern Uganda: burden, risk factors and impact on outcomes (The Wayo-Nero Study).

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    Mugisha, James; Muyinda, Herbert; Malamba, Samuel; Kinyanda, Eugene

    2015-03-14

    Major depressive disorder (MDD) is a major public health burden in conflict areas. However, it is not known for how long and by how much the observed high rates of MDD seen in conflict settings persist into the post-conflict period. A cross sectional survey was employed seven years after the conflict in northern Uganda had ended in the three districts of Amuru, Gulu and Nwoya. The prevalence of major depressive disorder (MDD) was 24.7% (95% CI: 22.9%-26.4%). The distribution by gender was females 29.2% (95% CI: 14.6%-19.5%) and males 17.0% (95% CI: 26.9%-31.5%). The risk factors for MDD fell under the broad domains of socio-demographic factors (female gender, increasing age, being widowed and being separated/divorced); distal psychosocial vulnerability factors ( being HIV positive, low social support, increasing war trauma events previously experienced, war trauma stress scores previously experienced, past psychiatric history, family history of mental illness, negative coping style, increasing childhood trauma scores, life-time attempted suicide, PTSD, generalized anxiety disorder and alcohol dependency disorder) and the psychosocial stressors (food insufficiency, increasing negative life event scores, increasing stress scores). 'Not receiving anti-retroviral therapy' for those who were HIV positive was the only negative clinical and behavioral outcome associated with MDD. These findings indicate that post-conflict northern Uganda still has high rates for MDD. The risk factors are quite many (including psychiatric, psychological and social factors) hence the need for effective multi-sectoral programs to address the high rates of MDD in the region. These programs should be long term in order to address the long term effects of war. Longitudinal studies are recommended to continuously assess the trends of MDD in the region and remedial action taken.

  2. Association of Waist Circumference Gain and Incident Prediabetes Defined by Fasting Glucose: A Seven-Year Longitudinal Study in Beijing, China

    Directory of Open Access Journals (Sweden)

    Li-Xin Tao

    2017-10-01

    Full Text Available The risk of incident prediabetes with gain in waist circumference (WC has not been addressed among Chinese adults. A total of 7951 participants who underwent health check-ups at the Beijing Physical Examination Center and Beijing Xiaotangshan hospital were recruited in 2009 and followed up in 2016. Participants were classified into four groups according to categories of percent WC gain: ≤−2.5%, −2.5–2.5%, 2.5–5%, and >5%. The effect of WC gain on prediabetes was evaluated using modified Poisson regression models. Over seven years of follow-up, we identified 1034 prediabetes cases (413 women. Compared with a WC gain of ≤−2.5%, participants with a WC gain of >5% have a higher risk of prediabetes, be they male (non-abdominal obesity at baseline group: RR = 1.57, 95% CI: 1.10–2.24, abdominal obesity at baseline group: RR = 1.66, 95% CI: 1.20–2.30 or female (non-abdominal obesity at baseline group: RR = 1.74, 95% CI: 1.14–2.64, abdominal obesity at baseline group: RR = 2.47, 95% CI: 1.43–4.28. In conclusion, the risk of prediabetes increased significantly with increasing WC for both genders in the Chinese population. Lifestyle interventions aiming at preventing abdominal obesity are urgently needed to reduce the increasing burden of prediabetes, diabetes, and its complications.

  3. Breastfeeding, weight gain in infancy, and overweight at seven years of age - The prevention and incidence of asthma and mite allergy birth cohort study

    NARCIS (Netherlands)

    Scholtens, Salome; Gehring, Ulrike; Brunekreef, Bert; Smit, Henriette A.; de Jongste, Johan C.; Kerkhof, Marjan; Gerritsen, Jorrit; Wijga, Alet H.

    2007-01-01

    Compared with nonbreastfed children, breastfed children tend to have a lower body mass index (BMI) at about 1 year of age. How the BMI of breastfed children develops after the first year when this difference in BMI at 1 year of age is considered is not clear. The authors studied the association

  4. MasterOnline Periodontology and Implant Therapy-revisited after seven years: A case study of the structures and outcomes in a blended learning CPD.

    Science.gov (United States)

    Ratka-Krüger, P; Wölber, J P; Blank, J; Holst, K; Hörmeyer, I; Vögele, E

    2018-02-01

    There is a great need for postgraduate training and continuing professional development (CPD), specifically in the field of periodontology. Despite the plenty of periodontal CPDs, there is a lack of information about the performance of CPDs in a blended learning setting. This study is a case study of the structures and outcomes in a blended learning CPD programme in periodontology, the MasterOnline Periodontology and Implant Therapy hosted by the University of Freiburg's Dental School. The structures of the blended learning CPD were analysed with the aims to (i) make explicit how various innovative educational methods and ICT tools can be successfully applied to a Web-supported postgraduate periodontology training programme, (ii) identify the programme's impact on learning transfer in students' dental practices and (iii) identify other outcomes, synergies and any changes required during the existence. Using qualitative interviewing, the various types of learning transfer and elements of the study programme that foster transfer could be exemplified. A period of 7 years was analysed. In this duration, 50 students successfully graduated to a master of science. Qualitative interviews were performed with six students and four teachers affirming the learning transfer in a blended learning setting. This case study shows that blended learning can be a successful approach for CPD in dentistry. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Infrequent word classes in the speech of two- to seven-year-old children with cochlear implants and their normally hearing peers: a longitudinal study of adjective use.

    Science.gov (United States)

    Tribushinina, Elena; Gillis, Steven; De Maeyer, Sven

    2013-03-01

    Studies investigating language skills of children after cochlear implantation usually use global language proficiency scores and rarely tackle the acquisition of specific language phenomena (word classes, grammatical constructions, etc.). Furthermore, research is largely restricted to frequent word classes (nouns, verbs). The present study targets the acquisition of adjectives (e.g. big, intelligent) by children implanted before their second birthday. Adjectives constitute a relatively infrequent, but functionally important word class and were shown to be good indicators of language delays and impairments. Nine cochlear-implanted (CI) children and 60 age-matched normally hearing (NH) controls participated in the study. The CI children were followed longitudinally from ages 2 to 7; control data were collected in a cross-sectional manner (10 children per age group). Samples of children's spontaneous interactions with their caregivers were transcribed and analyzed for adjective use (frequency, lexical diversity, complexity of syntactic constructions, and morphological correctness). The performance of the CI subjects was not significantly different from that of NH peers on adjective frequency and lexical diversity. On these measures, both groups reached adult levels by age 3. However, the CI group had a significant delay in the acquisition of complex syntactic constructions. The NH subjects produced adjectives in adult-like grammatical constructions from age 3 onwards, whereas their CI peers lagged behind until age 5. The speech of the CI participants also featured morphological errors that are not characteristic of typical development (inflection of predicative adjectives). However, the overall error rate was low. The findings suggest that CI children have particular difficulty with grammatical items (bound morphemes, copulas) that are less salient in the flow of speech than content words. Nevertheless, children implanted before their second birthday are able to catch

  6. Twenty-Seven-Year Follow-Up of Vietnam Air War USAF POWs and Matched Controls Not Captured: A Qualitative Study.

    Science.gov (United States)

    Sledge, William; Rozanova, Julia; Dorset, Julianne

    2018-03-13

    To provide a follow up of a 1976 study of the impact of captivity on U.S. Air Force (USAF) POWs and USAF Controls matched for time in Southeast Asia, military rank and aircraft crew position. Qualitative study of replies to open ended questions of positive and negative changes due to their captivity/combat experiences made by participants (POWs and Controls) who replied in both 1976 and in 2003. Both groups acknowledged positive and negative effects of the experiences in 1976. In 1976 and 2003 the POWs mainly reported negative effects on career and family domains but positive effects of individual development and growth. Controls reported mild negative effects on family in 1976, and benefits to their careers and sense of self in both 1976 and 2003. Captivity during the Vietnam War for USAF included two types of extreme duress which were the incarceration itself; and the repatriation experience which entailed re-assimilation despite loss of occupation and disrupted families. Despite these obstacles, POWs exhibited substantial resilience in achieving self-growth and how they regarded themselves psychologically in comparison to their matched control fellow aviators who while also suffering a lesser separation from family, tended to prosper in their careers and were proud of their accomplishments. Long term separation from work, family and friends and the inability to return to their families and careers with the effectiveness demanded by their ambition were a more devastating ongoing consequence of their captivity than the immediate suffering of their imprisonment.

  7. The prevalence of depressive symptoms among fathers and associated risk factors during the first seven years of their child’s life: findings from the Millennium Cohort Study

    Directory of Open Access Journals (Sweden)

    Selina Nath

    2016-06-01

    Full Text Available Abstract Background Increasing evidence suggests that postnatal paternal depression is associated with adverse emotional, behavioural and cognitive outcomes in children. Despite this, few studies have determined the prevalence of fathers’ depressive symptoms during the first few years of their children’s lives and explored what factors are related to these symptoms. We estimated the prevalence and examined associated risk factors of paternal depressive symptoms in a nationally representative sample of fathers with children aged between 9 months and 7 years old from the Millennium cohort study. The risk factors examined were maternal depressive symptoms, marital conflict, child temperament, child gender, paternal education, fathers’ ethnic background, fathers’ employment status, family housing, family income and paternal age. Methods Secondary data analysis was conducted using the UK Millennium cohort study, which consisted of data from England, Scotland, Wales and Northern Ireland of families with infants born in the year 2000/2001. Data from four sweeps were used from when children in the cohort were aged 9 months, 3, 5 and 7 years old (n = 5155–12,396. Results The prevalence of paternal depressive symptoms over time was 3.6 % at 9 months, 1.2 % at 3 years old, 1.8 % at 5 years and 2.0 % at 7 years (using Kessler cut-off points to categorise high depressive symptoms vs low depressive symptoms. Linear regression trends (using continuous measures of depressive symptoms indicated that both paternal and maternal depressive symptoms decreased over time, suggesting similar patterns of parents’ depressive symptoms after the birth of a child, but the decrease was more evident for mothers. Paternal depressive symptoms were consistently associated with fathers’ unemployment, maternal depressive symptoms and marital conflict. Socioeconomic factors such as rented housing when child was 9 months and low family income when

  8. The prevalence of depressive symptoms among fathers and associated risk factors during the first seven years of their child's life: findings from the Millennium Cohort Study.

    Science.gov (United States)

    Nath, Selina; Psychogiou, Lamprini; Kuyken, Willem; Ford, Tamsin; Ryan, Elizabeth; Russell, Ginny

    2016-06-13

    Increasing evidence suggests that postnatal paternal depression is associated with adverse emotional, behavioural and cognitive outcomes in children. Despite this, few studies have determined the prevalence of fathers' depressive symptoms during the first few years of their children's lives and explored what factors are related to these symptoms. We estimated the prevalence and examined associated risk factors of paternal depressive symptoms in a nationally representative sample of fathers with children aged between 9 months and 7 years old from the Millennium cohort study. The risk factors examined were maternal depressive symptoms, marital conflict, child temperament, child gender, paternal education, fathers' ethnic background, fathers' employment status, family housing, family income and paternal age. Secondary data analysis was conducted using the UK Millennium cohort study, which consisted of data from England, Scotland, Wales and Northern Ireland of families with infants born in the year 2000/2001. Data from four sweeps were used from when children in the cohort were aged 9 months, 3, 5 and 7 years old (n = 5155-12,396). The prevalence of paternal depressive symptoms over time was 3.6 % at 9 months, 1.2 % at 3 years old, 1.8 % at 5 years and 2.0 % at 7 years (using Kessler cut-off points to categorise high depressive symptoms vs low depressive symptoms). Linear regression trends (using continuous measures of depressive symptoms) indicated that both paternal and maternal depressive symptoms decreased over time, suggesting similar patterns of parents' depressive symptoms after the birth of a child, but the decrease was more evident for mothers. Paternal depressive symptoms were consistently associated with fathers' unemployment, maternal depressive symptoms and marital conflict. Socioeconomic factors such as rented housing when child was 9 months and low family income when child was 5 and 7 years were also associated with higher paternal

  9. A Seven-Year Major and Trace Element Study of Rain Water in the Barcés River Watershed, A Coruña, NW Spain

    Science.gov (United States)

    Delgado, Jordi; Cereijo-Arango, José Luis; Juncosa-Rivera, Ricardo

    2016-04-01

    Precipitation constitutes an important source of soluble materials to surface waters and, in areas where they are diluted precipitation (either dry or wet) it can be the most relevant solute source. Certain trace elements may have a limited natural availability in soils and rocks although they can be important with respect the operation of different biogeochemical cycles, for the computation of local/regional atmospheric pollutant loads or from the global mass budget. In the present study we report the results obtained in a long-lasting (December 2008-December 2015) monitoring survey of the chemical composition of bulk precipitation as monthly-integrated samples taken at the headwaters of the Barcés river watershed (A Coruña, Spain). This location was selected based on the necessity of quantification of the chemical composition and elemental loads associated with the different water types (stream water, ground water and precipitation) contributing to the flooding of the Meirama lake. Available data includes information on meteorological parameters (air temperature, relative humidity, atmospheric pressure, wind speed and direction, total and PAR radiation and precipitation) as well as a wide bundle of physico-chemical (pH, redox, electrical conductivity, alkalinity, Li, Na, K, Mg, Ca, Sr, Mn, Fe, NH4, Cs, Rb, Ba, Zn, Cu, Sb, Ni, Co, Cr, V, Cd, Ag, Pb, Se, Hg, Ti, Sn, U, Mo, F, Cl, Br, SO4, NO3, NO2, Al, As, PO4, SIO2, B, O2, DIC, DOC) and isotopic (18Ov-smow and 2Hv-smow) constituents. The average pH of local precipitation is 5.6 (n=65) which is consistent with the expected value for natural, unpolluted rain water. Most of the studied elements (eg. Na, Ca, K, Mg, SiO2, etc.) shows significant increases in their concentration in the dry period of the year. That points towards a more significant contribution of dry deposition in these periods compared with the wet ones. The average electrical conductivity is about 67 S/cm while the average chloride

  10. Seven-year follow-up study of symptoms in asylum seekers and refugees with PTSD treated with trauma-focused groups.

    Science.gov (United States)

    Drožđek, Boris; Kamperman, Astrid M; Tol, Wietse A; Knipscheer, Jeroen W; Kleber, Rolf J

    2014-04-01

    To examine sustainability of symptom outcomes of a 1-year phase-based trauma-focused, multimodal, and multicomponent group therapy in a day treatment program for posttraumatic stress disorder (PTSD) over an average period of 7 years. Iranian and Afghan patients (N = 69) were assessed with self-rated symptom checklists for PTSD, anxiety, and depression symptoms before (T1), after (T2), and up to 11 years upon completion of the treatment (T3). A series of mixed model regression analyses was applied to determine the course of the measured symptoms over time. At T2, all symptoms were reduced, but PTSD symptoms showed the strongest reduction. The trend of symptom reduction continued up to 5 years posttreatment and was similar for all the examined symptoms. After 5 years, all symptoms started to worsen, but remained under baseline levels at T3. The applied treatment appears to improve mental health of the studied sample on both the short and longer term. © 2013 Wiley Periodicals, Inc.

  11. Low volumetric BMD is linked to upper-limb fracture in pubertal girls and persists into adulthood: a seven-year cohort study.

    Science.gov (United States)

    Cheng, Sulin; Xu, Leiting; Nicholson, Patrick H F; Tylavsky, Frances; Lyytikäinen, Arja; Wang, Qingju; Suominen, Harri; Kujala, Urho M; Kröger, Heikki; Alen, Markku

    2009-09-01

    The aetiology of increased incidence of fracture during puberty is unclear. This study aimed to determine whether low volumetric bone mineral density (vBMD) in the distal radius is associated with upper-limb fractures in growing girls, and whether any such vBMD deficit persists into adulthood. Fracture history from birth to 20 years was obtained and verified by medical records in 1034 Finnish girls aged 10-13 years. Bone density and geometry at distal radius, biomarkers and lifestyle/behavioural factors were assessed in a subset of 396 girls with a 7.5-year follow-up. We found that fracture incidence peaked during puberty (relative risk 3.1 at age of 8-14 years compared to outside this age window), and 38% of fractures were in the upper-limb. Compared to the non-fracture cohort, girls who sustained upper-limb fracture at ages 8-14 years had lower distal radial vBMD at baseline (258.9+/-37.5 vs. 287.5+/-34.1 mg/cm(3), p=0.001), 1-year (252.0+/-29.3 vs. 282.6+/-33.5 mg/cm(3), p=0.001), 2-year (258.9+/-32.2 vs. 289.9+/-40.1 mg/cm(3), p=0.003), and 7-year follow-ups (early adulthood, 307.6+/-35.9 vs. 343.6+/-40.9 mg/cm(3), p=0.002). There was a consistent trend towards larger bone cross-sectional area in the fracture cohort compared to non-fracture. In a logistic regression model, lower vBMD (p=0.001) was the only significant predictor of upper-limb fracture during the period of 8-14 years. Our results indicate that low BMD is an important factor underlying elevated upper-limb fracture risk during puberty, and that low BMD in pubertal girls with fracture persists into adulthood. Hence low vBMD during childhood is not a transient deficit. Methods to monitor vBMD and to maximise bone mineral accrual and reduce risks of falling in childhood should be developed.

  12. Physical health-related quality of life predicts disability pension due to musculoskeletal disorders: seven years follow-up of the Hordaland Health Study Cohort.

    Science.gov (United States)

    Haukenes, Inger; Farbu, Erlend H; Riise, Trond; Tell, Grethe S

    2014-02-14

    Musculoskeletal diseases are characterized by a high degree of comorbidity with common mental disorders and are a major cause of health-related exclusion from working life. Using a prospective design we aimed to examine the relative importance of physical and mental health-related quality of life as predictors of disability pension due to musculoskeletal diseases. A subsample (N = 18,581) born 1953-1957, participated in the The Hordaland Health Study (HUSK) during 1997-1999, and was followed through December 31st 2004. Baseline measures of health-related quality of life were estimated using the Physical (PCS) and Mental Component Summary (MCS) of the Short Form-12 (SF-12). Further information on education, occupation, smoking, physical activity, number of musculoskeletal pain sites and BMI were provided by questionnaires and health examination. The association between self-perceived physical and mental health and subsequent disability pension, obtained from the national database of health and social benefits was estimated using Cox regression analyses. Participants reporting poor physical health (quartile 1) had a marked increased risk for disability pension due to musculoskeletal diseases (age and gender-adjusted hazard ratio = 22.1, 95% CI = 12.5-39.0) compared with those reporting good/somewhat good physical health (quartiles 4 and 3 combined). Adjustment for socioeconomic status and lifestyle factors slightly attenuated the association (hazard ratio = 16.7), and adding number of reported pain sites weakened the association even more (hazard ratio = 7.1, 95% CI = 3.8-12.8). Also, participants reporting poor mental health had a higher risk for disability pension due to musculoskeletal diseases (age and gender adjusted hazard ratio = 1.8, 95% CI = 1.3-2.6); however, in the final model the risk was not statistically significant. The physical component in health-related quality of life (SF-12) was a strong predictor of disability

  13. CEBAF celebrates seven years of physics

    International Nuclear Information System (INIS)

    Higinbotham, Douglas

    2003-01-01

    Jefferson Lab in Newport News, Virginia, recently celebrated the first seven years of physics with the Continuous Electron Beam Accelerator Facility, CEBAF. The unique design of this electron accelerator allows three experimental halls to be operated simultaneously, with a total beam current of 200 (micro)A and a beam polarization of up to 80%. With this facility, a user community of more than 1000 scientists from 187 institutions in 20 countries has completed 81 nuclear-physics experiments, with substantial data taken on 23 more. From the data obtained in these experiments, more than 250 refereed journal articles have been published and 146 doctoral degrees have been awarded. In the near future more than 60 experiments are planned, and there are currently 128 PhD theses in progress. To celebrate and review these accomplishments, while also looking toward the future, the Jefferson Lab user group board of directors organized a symposium, which was held on 11-13 June and dedicated to the memory of Nathan Isgur, Jefferson Lab's first chief scientist. The meeting was divided into eight physics topics: nucleon form factors, few-body physics, reactions involving nuclei, strangeness production, structure functions, parity violation, deep exclusive reactions and hadron spectroscopy. Each topic was presented by one experimentalist and one theorist

  14. Short sleep duration, shift work, and actual days taken off work are predictive life-style risk factors for new-onset metabolic syndrome: a seven-year cohort study of 40,000 male workers.

    Science.gov (United States)

    Itani, Osamu; Kaneita, Yoshitaka; Tokiya, Mikiko; Jike, Maki; Murata, Atsushi; Nakagome, Sachi; Otsuka, Yuichiro; Ohida, Takashi

    2017-11-01

    This longitudinal study investigated the effects of various lifestyle-related factors - including sleep duration, shift work, and actual days taken off work - on new-onset metabolic syndrome (MetS). A total of 39,182 male employees (mean age 42.4 ± 9.8 years) of a local government organization in Japan were followed up for a maximum of seven years, between 1999 and 2006. Multivariate analysis (Cox proportional hazard method) identified seven high-risk lifestyle factors that were significantly associated with new-onset MetS or a range of metabolic factors (obesity, hypertension, hyperglycemia, dyslipidemia): (1) short sleep duration (work, (3) insufficient number of days off work, (4) always eating until satiety, (5) not trying to take every opportunity to walk, (6) alcohol intake ≥60 g/day, and (7) smoking. In addition, a higher number of these high-risk lifestyle factors significantly promoted the onset of MetS. The hazard ratio for MetS associated with 0-1 high-risk lifestyle parameters per subject at the baseline was set at 1.00. Hazard ratios associated with the following numbers of high-risk lifestyle parameters were: 1.22 (95% CI 1.15-1.29) for 2-3 of these parameters; and 1.43 (1.33-1.54) for 4-7. An increase in the number of high-risk lifestyle factors - such as short sleep duration, shift work, and an insufficient number of days off work - increased the risk of MetS onset. Comprehensive strategies to improve a range of lifestyle factors for workers, such as sleep duration and days off work, could reduce the risk of MetS onset. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Response problems in a vacation panel study

    Science.gov (United States)

    Christine A. Vogt; Susan I. Stewart

    2001-01-01

    This paper investigates response problems encountered in a panel study of travel behavior. Though the overall response rate to the three-wave panel study was acceptable (over 60%), three types of response problems were encountered: refusal, non-response, and attrition. In a follow-up phone survey, a sample of individuals from each problem response group was questioned...

  16. Practice Makes Perfect? Skills Gained in Seven Years of Questionnaires.

    Science.gov (United States)

    Jackson, Elaine E.; Schuyler, Nancy B.

    Based on seven years of surveying students, parents, and educators, the following conclusions were reached: (1) preliminary telephoning of graduates to verify addresses did not produce higher returns from those contacted; (2) cover letters printed on more expensive colored-letterhead stationary did not produce a higher return rate than the same…

  17. Soft drink intake at age six and nine and the association with BMI three and seven years later - A follow-up study based on the Copenhagen School Child Intervention Study (CoSCIS)

    DEFF Research Database (Denmark)

    Jensen, Britt Wang; Nielsen, Birgit Marie; Husby, Ida

    Introduction: The consumption of sugar-sweetened beverages is one of the few dietary components that have been associated with the development of obesity. However, most previous studies have been based on children or adolescents aged 8 years or more. Method: The study was based on the Copenhagen......-days pre-printed food record. Analyses were conducted using the mixed model approach for repeated measurements and were adjusted for gender, puberty, parental BMI, municipality, school, baseline BMI, SES and physical activity. Results: 154 children, 68 boys and 86 girls were included in the analyses....... Mean intake of soft drinks was 0.14 l/d at age 6 and 0.12 l/d at age 9 (difference p=0.08). No associations were found between intake of soft drink at age 6 and BMI at age 13 (b:-0.8; p=0.91), or intake at age 9 and BMI at age 13 (b:-0.3; p= 0.80). Neither was the change in intake of soft drinks from...

  18. General health status and changes in chewing ability in older Canadians over seven years.

    Science.gov (United States)

    Locker, David; Matear, David; Lawrence, Herenia

    2002-01-01

    The purpose of this study was to describe the onset of and recovery from chewing problems in an older adult population over a seven-year period and to describe factors associated with these changes. Of particular interest was the relationship between general health and changes in oral functioning. The data came from a longitudinal study of community-dwelling individuals who were aged 50 years and older when first recruited. Data were collected at baseline (n = 907) and at three (n = 611) and seven-year (n = 425) follow-ups. Oral function was assessed by means of a six-item index of chewing ability. Data were weighted to account for loss to follow-up using weights derived from the seven-year response proportions for dentate and edentulous subjects. Logistic regression analysis using backward stepwise selection was used to identify predictors of onset and recovery. At baseline, 25 percent of subjects reported a problem chewing. This rose to 26 percent at three years and 34 percent at seven years. The seven-year incidence of chewing dysfunction was 19 percent. Of those with a chewing problem at baseline, 21 percent did not have a problem at seven years. A logistic regression model predicting the seven-year incidence of chewing problems indicated that subjects aged 65 years or older, the edentulous, those rating their oral health as poor, those without dental insurance and those without a regular source of dental care were more likely to be an incident case. In addition, a variable denoting the number of chronic medical conditions at baseline also entered the model. A logistic regression model predicting recovery indicated that older subjects, the edentulous, those from low-income households, and those with limitations in activities of daily living were less likely to recover over the observation period. The results of this study indicate a marked increase in the prevalence of chewing problems in this older adult population over the seven-year observation period

  19. Exercise-Induced Ventricular Fibrillation: Seven Years Follow-Up

    Directory of Open Access Journals (Sweden)

    Gökmen Gemici

    2011-11-01

    Full Text Available We present a 7-year follow-up of a 55-year-old male who experienced ventricular fibrillation during the recovery period of exercise testing and refused implantation of an ICD. Normal left ventricular systolic function was found on echocardiographic examination, and coronary angiography revealed only a side branch disease with a vessel diameter of less than 2 millimeters. The patient was discharged on metoprolol and ASA in addition to his previous treatment with lisinopril and simvastatin. Outpatient cardiac evaluation by repeated 24-hour ECG monitorizations (Holter revealed normal findings. On follow up visits every six months for the past seven years, the patient was found to be asymptomatic.

  20. A craniopharyngioma in a seven-year-old dog

    International Nuclear Information System (INIS)

    Eckersley, G.N.; Kriek, N.P.J.; Geel, J.K.

    1991-01-01

    A seven-year-old male Border Collie was presented with a history of lethargy, episodic circling, incoordination and polydypsia. Physical examination revealed depression, obesity and bradycardia. A neurological examination indicated the possible presence of a space-occupying lesion in the brain. Results of the clinical investigation revealed hyposthenuria, sinus bradycardia and increased concentration of protein in the cerobrospinal fluid. A computerised axial tomography scan revealed a mass in the region of the hypophysis. The dog was euthanased and a post mortem examination confirmed the presence of a craniopharyngioma. 17 refs., 3 figs

  1. Efficient panel designs for longitudinal recurrent event studies recording panel counts.

    Science.gov (United States)

    Juarez-Colunga, Elizabeth; Dean, C B; Balshaw, Robert

    2014-04-01

    Many clinical trials are designed to study outcome measures recorded as the number of events occurring during specific intervals, called panel data. In such data, the intervals are specified by a planned set of follow-up times. As the collection of panel data results in a partial loss of information relative to a record of the actual event times, it is important to gain a thorough understanding of the impact of panel study designs on the efficiency of the estimates of treatment effects and covariates. This understanding can then be used as a base from which to formulate appropriate designs by layering in other concerns, e.g. clinical constraints, or other practical considerations. We compare the efficiency of the analysis of panel data with respect to the analysis of data recorded precisely as times of recurrences, and articulate conditions for efficient panel designs where the focus is on estimation of a treatment effect when adjusting for other covariates. We build from the efficiency comparisons to optimize the design of panel follow-up times. We model the recurrent intensity through the common proportional intensity framework, with the treatment effect modeled flexibly as piecewise constant over panels, or groups of panels. We provide some important considerations for the design of efficient panel studies, and illustrate the methods through analysis of designs of studies of adenomas.

  2. Long-term safety and efficacy of a cholesterol-lowering diet in children with elevated low-density lipoprotein cholesterol : Seven-year results of the Dietary Intervention Study in Children (DISC)

    NARCIS (Netherlands)

    Obarzanek, E; Kimm, SYS; Barton, BA; Van Horn, L; Kwiterovich, PO; Simons-Morton, DG; Hunsberger, SA; Lasser, NL; Robson, AM; Franklin, FA; Lauer, RM; Stevens, VJ; Friedman, LA; Dorgan, JF; Greenlick, MR

    Objective. Diets reduced in fat and cholesterol are recommended for children over 2 years of age, yet long-term safety and efficacy are unknown. This study tests the long-term efficacy and safety of a cholesterol-lowering dietary intervention in children. Methods. Six hundred sixty-three children 8

  3. The solar house of CRESESB: seven years of success

    Energy Technology Data Exchange (ETDEWEB)

    Galdino, Marco Antonio; Souza, Hamilton Moss de, E-mail: marcoag@cepel.br

    2005-07-01

    The solar house is located in the facilities of CEPEL - Centro de Pesquisas de Energia Eletrica (Electric Power Research Centre) at Fundao Island, Rio de Janeiro, Brazil. It is powered by a stand-alone PV system and is operated by CRESESB - Centro de Referencia para Energia Solar e Eolica Sergio de Salvo Brito (Reference Centre for Solar and Wind Energy Sergio de Salvo Brito) as a demonstration centre. The solar house was built in 1997, and during seven years of operation it received about 9.000 visitors (up to middle 2004). The present paper shares some aspects of the experience gained with the solar house, including technical details of the systems installed, the experience in operation and maintenance, and the divulgation and training of personnel so far obtained. (author)

  4. Satisfaction with primary care and mental health care among individuals with severe mental illness in a rural area: a seven-year follow-up study of a clinical cohort.

    Science.gov (United States)

    Ruud, Torleif; Aarre, Trond F; Boeskov, Berit; le Husevåg, Per Stå; Klepp, Rigmor; Kristiansen, Synnøve Alet; Sandvik, Jorunn

    2016-01-01

    Most studies of services for people with severe mental illness have been performed in cities. Our 7-year follow-up study aimed to investigate clinical course and satisfaction with services among individuals with severe mental illness who received community mental health services in a rural area. The services were provided by primary care and a community mental health center (CMHC), which worked in close collaboration and emphasized individually tailored case management, relationship-building and continuity of care. All 57 patients with severe mental illness who were seen by the CMHC in 1992-1993 and were still alive in 1999 were asked to participate. Retrospective ratings were performed for the first month of contact in 1992-1993 based on patient records and detailed notes. A semi-structured interview was conducted in 1999-2000 with the 40 patients (70.2 %) who gave written consent to participate in the study. DSM-IV diagnoses were made using OPCRIT. The retrospective baseline ratings and the follow-up interview included assessments of symptoms and functioning using the following instruments: the Brief Psychiatric Rating Scale Expanded version 4 (BPRS-E), the Health of the Nation Outcome Scales (HoNOS), the Global Assessment of Functioning Scale (split version), and the Practical and Social Functioning Scale (PSF). The ratings revealed improvements in psychiatric problems and functioning. Patients with schizophrenia spectrum disorders improved primarily in psychotic symptoms, while patients with severe affective disorders improved primarily in affective symptoms. Large variations in the use of primary care and mental health services were observed, with more intensive specialized mental health services for individuals with schizophrenia spectrum disorders than severe affective disorders. Overall, the patients were satisfied with the provided services. They were most satisfied with GPs and more satisfied with local outpatient and inpatient services than with

  5. Community-associated methicillin-resistant Staphylococcus aureus infections in Aboriginal children attending hospital emergency departments in a regional area of New South Wales, Australia: a seven-year descriptive study

    Directory of Open Access Journals (Sweden)

    Susan Thomas

    2017-12-01

    Full Text Available Objective: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA can cause bacterial skin infections that are common problems for Aboriginal children in New South Wales (NSW. MRSA is not notifiable in NSW and surveillance data describing incidence and prevalence are not routinely collected. The study aims to describe the epidemiology of CA-MRSA in Aboriginal children in the Hunter New England Local Health District (HNELHD. Methods: We linked data from Pathology North Laboratory Management System (AUSLAB and the HNELHD patient administration system from 33 hospital emergency departments. Data from 2008–2014 for CA-MRSA isolates were extracted. Demographic characteristics included age, gender, Aboriginality, rurality and seasonality. Results: Of the 1222 individuals in this study, 408 (33.4% were Aboriginal people. Aboriginal people were younger with 45.8% aged less than 10 years compared to 25.9% of non-Aboriginal people. Most isolates came from Aboriginal people who attended the regional Tamworth Hospital (193/511 isolates from 149 people. A larger proportion of Aboriginal people, compared to non-Aboriginal people, resided in outer regional (64.9% vs 37.2% or remote/very remote areas (2.5% vs 0.5%. Most infections occurred in summer and early autumn. For Aboriginal patients, there was a downward trend through autumn, continuing through winter and spring. Discussion: Aboriginal people at HNELHD emergency departments appear to represent a greater proportion of people with skin infections with CA-MRSA than non-Aboriginal people. CA-MRSA is not notifiable in NSW; however, pathology and hospital data are available and can provide valuable indicative data to health districts for planning and policy development.

  6. First line treatment of pemphigus vulgaris with a novel protocol in patients with contraindications to systemic corticosteroids and immunosuppressive agents: Preliminary retrospective study with a seven year follow-up.

    Science.gov (United States)

    Ahmed, A Razzaque; Nguyen, Tegan; Kaveri, Srini; Spigelman, Zachary S

    2016-05-01

    Conventional therapy for pemphigus vulgaris (PV) consists of high-dose systemic corticosteroids (CS) and immunosuppressive agents (ISA). This combination may be ineffective, cause serious adverse events or relapses in some patients. To determine if the combination of intravenous immunoglobulin (IVIg) therapy and rituximab (RTX) can be used as first-line therapy in PV patients in whom systemic CS and ISA are contraindicated and evaluate its ability to produce long-term sustained remissions. This a retrospective study of five male and five female patients (mean age 47.87 years). RTX was administered once weekly for eight consecutive weeks, followed by once monthly for four months (dose 375 mg/m(2)). Since CD20(+) B cells were undetectable, IVIg was infused until they reached normal levels (dose 2 g/kg/cycle). IVIg was then continued according to published protocol. Initial clinical response and complete disease resolution occurred in a mean of 3.2 weeks and 7.4 weeks, respectively. Mean duration of rituximab therapy was 6.09 months and 33.7 months for IVIg therapy. Mean duration of follow-up after the last dose of rituximab was 86.08 months, during which all patients remained in complete remission. Mean length of total follow-up was 103.99 months. No relapses, infections, or hospitalizations were reported. When systemic CS and ISA are contraindicated in PV patients, combination RTX and IVIg therapy can produce a prolonged, sustained remission without additional systemic therapy. This positive clinical outcome could be the consequence of pathogenic B cell depletion and restoration of immune regulation. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Case Study - Monitoring the Photovoltaic Panels

    OpenAIRE

    PACURAR Ana Talida; TOADER Dumitru; PACURAR Cristian

    2014-01-01

    The photovoltaic cell represents one of the most dynamic and attractive way to converts renewable energy sources in electricity production. That means to convert solar energy into electricity. In this paper is presented a analogy between two types of photovoltaic panels installed, with educational role for students. Also the objective of this paper is to estimate the performance of photovoltaic panels and to provide the best solution for industry. These two types of photovoltaic panels wer...

  8. CSF shunt infections in pediatrics. A seven-year experience.

    Science.gov (United States)

    Odio, C; McCracken, G H; Nelson, J D

    1984-12-01

    The medical records of children who had had CSF shunt procedures were reviewed for the seven-year period from 1975 through 1981. There were 516 procedures performed in 297 patients. Only three were ventriculoatrial shunts; the remainder were ventriculoperitoneal shunts. Fifty-nine infectious episodes (11%) occurred in 50 patients (17%); there were three relapses and six reinfections. The infecting pathogen was staphylococci in 75% of the infections and gram-negative bacilli in 19%, and there were two or more pathogens in 15% of the infections. The onset of the infection was within 15 days of surgery in 53% of the cases. The main symptoms were fever, irritability, and shunt malfunction. Gram's stain of the CSF was positive in 46% of the episodes and blood cultures were positive in 29%. Nineteen percent of patients had wound infection and 7% had peritonitis; in most of these cases there were no neurologic signs or symptoms. Thirteen episodes were managed with antibiotic therapy alone; among these, there were three relapses and two reinfections. Thirty-seven episodes were treated with antibiotics and immediate removal of the shunt; there were no relapses and three reinfections. Nine episodes were managed with antibiotics and delayed removal of the shunt; there was one reinfection. The median duration of antibiotic treatment was 15 days, and the time to defervescence was 24 hours in those with immediate removal of the shunt and six days in those in whom the shunt was not removed.

  9. Delamination tolerance studies in laminated composite panels

    Indian Academy of Sciences (India)

    Determination of levels of tolerance in delaminated composite panels is an important issue in composite structures technology. The primary intention is to analyse delaminated composite panels and estimate Strain Energy Release Rate (SERR) parameters at the delamination front to feed into acceptability criteria.

  10. Result of the arc of movement of lower cervical spine after seven years of arthroplasty

    Directory of Open Access Journals (Sweden)

    Luis Claudio de Velleca e Lima

    2014-09-01

    Full Text Available OBJECTIVE: To quantify the mobility of the lower cervical spine after seven years of total cervical disc replacement at two levels. METHOD: This clinical study was designed randomly and prospectively at the spine surgery center at the Hospital Nossa Senhora das Graças, in Canoas, RS-Brazil and at the Hospital Don João Becker, in Gravataí, RS-Brazil. Seventeen patients were included in the study that was designed to compare the data obtained from annual and sequential manner until the end of seven years. A comparison was made with the prior range of motion (ROM of each patient. All patients were diagnosed with not tractable symptomatic cervical degenerative disc disease with two adjacent levels between C-3 and C-7. RESULTS: A total of patients underwent TDR in two levels and at the end of seven years, only one patient was lost to follow-up. The pre and postoperative ROM was the same in the first three years however after the fourth year there was a gradual decline with a loss of 12% of preoperative ROM in flexion, 21% in extension and 23% in the right and left lateral bending at the end of seven years. CONCLUSIONS: The clinical outcome of this study is evidence level IV in evaluating the ROM for Moby-C(r for TDR in two adjacent levels at the lower cervical spine. These results show that the ROM is maintained during the first three years, gradually declining after that.

  11. Seven years experience with a computerized diabetes clinic database.

    Science.gov (United States)

    Flack, J R

    1995-01-01

    With the emergence of information technology applications in medicine, a computerized medical record system that could be used to : (1) maintain patients' clinical records over time, (2) communicate with referring practitioners, and (3) form the basis of a potential research database of information, was sought. In 1987, we developed such a clinical database to register patients attending our busy Diabetes Clinic, now seeing in excess of 300 new referrals and, on average, 3,000 clinic visits per year. Baseline demographic data, clinical history, and examination and investigation results are recorded. We also record diabetes therapy and other medication dosage and changes, monitor follow-up, assess health outcome information (such as stroke or amputation), and generate results, summaries, and reports to referring practitioners and other health professionals. We now have almost seven years of experience using the system. Initially established on a single PC with paper-based data collection and subsequent data entry (running as a DOS application), it is now established on a PC Local Area Network [LAN] with terminals in the clinic consultation rooms enabling direct data entry and allowing patients to view their results in graphic form on screen. From its inception, the Diabetes Clinic Database System has maintained patient demographic and clinical data (which facilitates efficient clinic management) with patient clinic lists and adhesive address labels generated from appropriate menus. Batch mode processing produces daily work sheets which facilitate the running of clinics as well as ad hoc, daily, and weekly reports for all patients (as required). This expedites correspondence with referring doctors. A quality assurance report to the clinic doctor highlights missing clinical information which must be obtained in order to ensure data completeness. The initial system was relatively inefficient in that it required data entry following patient consultation and provided no

  12. Case Study - Monitoring the Photovoltaic Panels

    Directory of Open Access Journals (Sweden)

    PACURAR Ana Talida

    2014-05-01

    Full Text Available The photovoltaic cell represents one of the most dynamic and attractive way to converts renewable energy sources in electricity production. That means to convert solar energy into electricity. In this paper is presented a analogy between two types of photovoltaic panels installed, with educational role for students. Also the objective of this paper is to estimate the performance of photovoltaic panels and to provide the best solution for industry. These two types of photovoltaic panels were monitored at the same time and taking into account the same weather conditions. In introduction of this paper is a short description regarding the silicon, because it is considered to be the most frequently used material for photovoltaic cell production at industrial level. In this context are mentioned below photovoltaic cells: mono-crystalline, polycrystalline, ribbon silicon and amorphous silicon (thin film cells. It is also presented for all these types of cells the structure, the function, the advantages and the disadvantages.

  13. Tympanogram findings in patients with cleft palates aged six months to seven years

    Science.gov (United States)

    Yanti, A.; Widiarni, D.; Alviandi, W.; Tamin, S.; Mansyur, M.

    2017-08-01

    Cleft palate is one of the most common congenital craniofacial deformities. Otitis media with effusion (OME) is a middle ear disease having a prevalence of almost 90% in patients with cleft palates. Tympanometry is a fast, safe, non-invasive, and easy tool for diagnosing middle ear disease qualitatively and quantitatively. Studies have been conducted using tympanometry to detect middle ear conditions in patients with cleft palates, but no research has studied tympanogram findings in patients with cleft palates in Indonesia. The aim of this study is to determine the tympanogram findings in Indonesian children aged six months to seven years with cleft palates. This is a cross-sectional study of 30 patients (17 males and 13 females) with Veau classification of palatal clefts aged six months to seven years (median 26.5 months) who underwent tympanometry examinations using a 226 Hztympanometer. Tympanograms were classified using the Jerger/Liden classification. Examinations of 58 ears found that type B tympanograms occurred most frequently (70.7%). The quantitative values of tympanometry analyzed included SAA (0.1-0.2 cm3), TPP value (-197.2-(-146.8 daPa)), Vec value (0.5-0.6 cm3), and gradient value (0.03-0.07 cm3). Using the Fisher test, a significant relationship was found between age and type of tympanogram (p = 0.0039) with the risk of type B and C tympanograms in infants (6-60 months) as high as 4.8 times that of children without cleft palates. The type B tympanogram was most frequently seen in patients with cleft palates aged six months to seven years old with the quantitative values of tympanometry lower than the normal values. Therefore, there was a significant difference in the type of tympanogram seen with age.

  14. Experimental study on behavior of GFRP stiffened panels under compression

    Science.gov (United States)

    Kankeri, Pradeep; Ganesh Mahidhar, P. K.; Prakash, S. Suriya; Ramji, M.

    2015-03-01

    Glass Fiber Reinforced Polymer (GFRP) materials are extensively used in the aerospace and marine industries because of their high strength and stiffness to weight ratio and excellent corrosion resistance. Stiffened panels are commonly used in aircraft wing and fuselage parts. The present study focuses on the behavior of composite stiffened panels under compressive loading. With the introduction of stiffeners to unstiffened composite plates, the structural stiffness of the panel increases resulting in higher strength and stiffness. Studies in the past have shown that the critical structural failure mode under compressive loading of a stiffened composite panel is by local buckling. The present study attempts to evaluate the mechanical behavior of composite stiffened panels under compression using blade stiffener configuration and in particular on the behavior of the skin- stiffener interface through experimental testing. A novel test fixture is developed for experimental testing of GFRP stiffened panels. A non-contact whole field strain analysis technique called digital image correlation (DIC) is used for capturing the strain and damage mechanisms. Blade stiffeners increased the strength, stiffness and reduced the out-of plane displacement at failure. The failure of both the unstiffened and stiffened panels was through local buckling rather than through material failure. DIC was able to capture the strain localization and buckling failure modes.

  15. Long-term outcome of patients with active ankylosing spondylitis with etanercept-sustained efficacy and safety after seven years

    Science.gov (United States)

    2013-01-01

    Introduction Data from clinical studies on the long-term efficacy and safety of anti-tumor necrosis factor (TNF)-α therapy in patients with ankylosing spondylitis (AS) are scarce. This is the first report on continuous treatment with the TNFα fusion protein etanercept over seven years (y). Methods Overall, 26 patients with active AS were initially treated with etanercept 2 × 25 mg s.c./week with no concomitant disease modifying anti-rheumatic drugs (DMARDs) or steroids. The clinical response was assessed by standardized parameters. The primary outcome was the proportion of patients in the Spondyloarthritis International Society (ASAS) partial remission at seven years. AS disease activity scores (ASDAS) for status and improvement were compared to conventional outcome measures. Results Overall, 21/26 patients (81%) completed two years of treatment and 16/26 patients (62%) completed seven years. In the completer analysis, 31% patients were in ASAS partial remission at seven years, while 44% patients showed an ASDAS inactive disease status. Mean Bath AS activity index (BASDAI) scores, which were elevated at baseline (6.3 ± 0.9), showed constant improvement and remained low: 3.1 ± 2.5 at two years and 2.5 ± 2.2 at seven years, while ASDAS also improved (3.9 ± 0.7 at baseline, 1.8 ± 0.9 at two years, 1.6 ± 0.8 at seven years), all P treatment due to adverse events. Patients who completed the study had lower baseline Bath AS function index (BASFI) scores vs. patients who discontinued. No other clinical parameter at baseline could predict any long-term outcome. Conclusions This study confirms the clinical efficacy and safety of etanercept in patients with active AS over seven years of continuous treatment. After seven years, more than half of the initially treated patients remained on anti-TNF therapy, and one-third were in partial remission. Trial Registration ClinicalTrials.gov: NCT01289743 PMID:23786760

  16. The impact of lifetime PTSD on the seven-year course and clinical characteristics of OCD.

    Science.gov (United States)

    Ojserkis, Rachel; Boisseau, Christina L; Reddy, Madhavi K; Mancebo, Maria C; Eisen, Jane L; Rasmussen, Steven A

    2017-12-01

    Research has suggested that the co-occurrence of PTSD in individuals with OCD is associated with more severe symptoms and less responsivity to empirically supported treatment as compared to individuals with OCD and no history of PTSD. However, much of this work has been limited by non-empirical case report design, cross-sectional and retrospective analyses, or small sample sizes. The current study extended this research by comparing the clinical characteristics of individuals with OCD with and without a lifetime PTSD diagnosis in a large, naturalistic, longitudinal sample over the course of seven years. At baseline, individuals with comorbid lifetime PTSD reported significantly more severe symptoms of OCD (including symptom levels and insight), lower quality of life, and higher rates of comorbid lifetime mood and substance use disorders than participants without lifetime PTSD. Further, individuals with comorbid OCD and lifetime PTSD reported significantly more severe OCD symptoms over the course of seven years than those without lifetime PTSD. These results are largely consistent with the existing literature and support the need to consider PTSD symptoms in the assessment and treatment of OCD. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Forest herbicide influences on floristic diversity seven years after broadcast pine release treatments in central Georgia, USA

    Science.gov (United States)

    Robert S. Boyd; John D. Freeman; James H. Miller; M. Boyd. Edwards

    1995-01-01

    Abstract. Maintenance of biodiversity is becoming a goal of forest management. This study determined effects of broadcast pine release herbicide treatments on plant species richness, diversity, and structural proportions seven years after treatment. Three study blocks were established in central Georgia. Plots 0.6-0.8 ha in size were planted to...

  18. Integrated thermal treatment systems study. Internal review panel report

    Energy Technology Data Exchange (ETDEWEB)

    Cudahy, J.; Escarda, T.; Gimpel, R. [and others

    1995-04-01

    The U.S. Department of Energy (DOE) Office of Technology Development (OTD) commissioned two studies to evaluate nineteen thermal treatment technologies for treatment of DOE mixed low-level waste. These studies were called the Integrated Thermal Treatment System (ITTS) Phase I and Phase II. With the help of the DOE Office of Environmental Management (EM) Mixed Waste Focus Group, OTD formed an ITTS Internal Review Panel to review and comment on the ITTS studies. This Panel was composed of scientists and engineers from throughout the DOE complex, the U.S. Environmental Protection Agency, the California EPA, and private experts. The Panel met from November 15-18, 1994 to review the ITTS studies and to make recommendations on the most promising thermal treatment systems for DOE mixed low-level wastes and on research and development necessary to prove the performance of the technologies. This report describes the findings and presents the recommendations of the Panel.

  19. Integrated thermal treatment systems study. Internal review panel report

    International Nuclear Information System (INIS)

    Cudahy, J.; Escarda, T.; Gimpel, R.

    1995-04-01

    The U.S. Department of Energy (DOE) Office of Technology Development (OTD) commissioned two studies to evaluate nineteen thermal treatment technologies for treatment of DOE mixed low-level waste. These studies were called the Integrated Thermal Treatment System (ITTS) Phase I and Phase II. With the help of the DOE Office of Environmental Management (EM) Mixed Waste Focus Group, OTD formed an ITTS Internal Review Panel to review and comment on the ITTS studies. This Panel was composed of scientists and engineers from throughout the DOE complex, the U.S. Environmental Protection Agency, the California EPA, and private experts. The Panel met from November 15-18, 1994 to review the ITTS studies and to make recommendations on the most promising thermal treatment systems for DOE mixed low-level wastes and on research and development necessary to prove the performance of the technologies. This report describes the findings and presents the recommendations of the Panel

  20. Personality Predicts Cognitive Function Over Seven Years in Older Persons

    Science.gov (United States)

    Chapman, Benjamin; Duberstein, Paul; Tindle, Hilary A; Sink, Kaycee M; Robbins, John; Tancredi, Daniel J.; Franks, Peter

    2011-01-01

    Objectives To determine whether Neuroticism, as well as the less-studied dimensions the Five Factor Model of personality (Extraversion, Openness to Experience, Agreeableness, and Conscientiousness) were associated with 7-year trajectories of cognitive functioning in older persons. Design Primary analysis of existing clinical trial data. Participants 602 persons of average age 79 at baseline. Measurements The NEO-Five Factor Inventory of personality, completed at baseline, and the modified Mini Mental Status Exam (3MSE) measured every 6 months for 7 years. Results Controlling for demographics, baseline morbidities including depression, health behaviors, Apolipoprotein E4 genotype, and self-rated health, higher Neuroticism was associated with worse average cognitive functioning and a steeper rate of decline over follow-up. Higher Extraversion and lower Openness were both associated with worse average cognitive functioning prospectively, while persons higher in Conscientiousness showed a slower rate of cognitive decline. Conclusions In addition to Neuroticism, other dispositional tendencies appear prognostically relevant for cognitive functioning in older persons. More work is needed to understand the mechanisms by which traits operate, as well as whether mitigation of certain dispositional tendencies can facilitate a better course of cognitive function. PMID:22735597

  1. The prevalence and causes of visual impairment in seven-year-old children.

    Science.gov (United States)

    Ghaderi, Soraya; Hashemi, Hassan; Jafarzadehpur, Ebrahim; Yekta, Abbasali; Ostadimoghaddam, Hadi; Mirzajani, Ali; Khabazkhoob, Mehdi

    2017-11-22

    To report the prevalence and causes of visual impairment in seven-year-old children in Iran and its relationship with socio-economic conditions. In a cross-sectional population-based study, first-grade students in the primary schools of eight cities in the country were randomly selected from different geographic locations using multistage cluster sampling. The examinations included visual acuity measurement, ocular motility evaluation, and cycloplegic and non-cycloplegic refraction. Using the definitions of the World Health Organization (presenting visual acuity less than or equal to 6/18 in the better eye) to estimate the prevalence of vision impairment, the present study reported presenting visual impairment in seven-year-old children. Of 4,614 selected students, 4,106 students participated in the study (response rate 89 per cent), of whom 2,127 (51.8 per cent) were male. The prevalence of visual impairment according to a visual acuity of 6/18 was 0.341 per cent (95 per cent confidence interval 0.187-0.571); 1.34 per cent (95 per cent confidence interval 1.011-1.74) of children had visual impairment according to a visual acuity of 6/18 in at least one eye. Sixty-six (1.6 per cent) and 23 (0.24 per cent) children had visual impairment according to a visual acuity of 6/12 in the worse and better eye, respectively. The most common causes of visual impairment were refractive errors (81.8 per cent) and amblyopia (14.5 per cent). Among different types of refractive errors, astigmatism was the main refractive error leading to visual impairment. According to the concentration index, the distribution of visual impairment in children from low-income families was higher. This study revealed a high prevalence of visual impairment in a representative sample of seven-year-old Iranian children. Astigmatism and amblyopia were the most common causes of visual impairment. The distribution of visual impairment was higher in children from low-income families. Cost

  2. Understanding the Attainment of Stable Housing: A Seven-Year Longitudinal Analysis of Homeless Adolescents.

    Science.gov (United States)

    Braciszewski, Jordan M; Toro, Paul A; Stout, Robert L

    2016-04-01

    Stable housing provides a solid foundation for youth development, making it an essential topic of study among young homeless people. Although gains have been made in research with adolescents and young adults experiencing homelessness, few longitudinal studies of this population exist, clouding the long-term housing outcome picture. The current study examined the course and risk factors for homelessness in a sample of 243 homeless adolescents followed over a seven-year period. The vast majority of youth returned to stable housing quickly; however, early experiences of homelessness, even at this young age, were observed to have a substantial negative impact on future housing. Participants from poorer neighborhoods and those identifying as ethnic minorities also took longer to achieve stable housing. The data suggest that family reunification interventions may serve this population well. Preparing youth for returning home may prevent subsequent homeless episodes, while also improving their overall functioning.

  3. Study of the plywood panels properties using geostatistic

    Directory of Open Access Journals (Sweden)

    Cleverson Pinheiro

    2016-12-01

    Full Text Available Plywood panels have multiple applications in construction, in the furniture industry and packaging. There is a need to improve techniques for assessing quality of these products. This paper proposed the use of geostatistics to evaluate the behavior of the of the plywood panel. The physical properties were analyzed (moisture content, density and water absorption in the full extent of the plywood panel of Eucalyptus sp., bonded with adhesive single-component polyurethane. For analysis, three panels of five layers, with dimensions of 350 x 350 x 15.5 mm each, were employed. The tests were based on the standards EN 323-2000, EN 322-2000 and ABNT NBR 9486- 2011. Statistical modeling was performed using the R software, using the methodology of geostatistics. The average results were compared with values reported in the literature. The average water absorption was 7% higher in comparison with other studies, which used urea formaldehyde. So, the product can be applied only to interior and their use is not advisable for floors; the average moisture content and density were within the average values found in the literature. The behavior of the properties analyzed using the geostatistical model was not homogeneous, with large variations. Geostatistics was considered an appropriate tool for the study of the variability of the plywood panel properties, and can be applied for better quality control of them.

  4. A panel study of nuclear energy consumption and economic growth

    International Nuclear Information System (INIS)

    Apergis, Nicholas; Payne, James E.

    2010-01-01

    This study examines the relationship between nuclear energy consumption and economic growth for sixteen countries within a multivariate panel framework over the period 1980-2005. Pedroni's (1999, 2004) heterogeneous panel cointegration test reveals there is a long-run equilibrium relationship between real GDP, nuclear energy consumption, real gross fixed capital formation, and the labor force with the respective coefficients positive and statistically significant. The results of the panel vector error correction model finds bidirectional causality between nuclear energy consumption and economic growth in the short-run while unidirectional causality from nuclear energy consumption to economic growth in the long-run. Thus, the results provide support for the feedback hypothesis associated with the relationship between nuclear energy consumption and economic growth.

  5. The impact of gender and parenthood on physicians' careers--professional and personal situation seven years after graduation

    OpenAIRE

    Buddeberg-Fischer, B; Stamm, M; Buddeberg, C; Bauer, G; Hämmig, O; Knecht, Michaela; Klaghofer, R

    2010-01-01

    Abstract Background The profile of the medical profession is changing in regard to feminization, attitudes towards the profession, and the lifestyle aspirations of young physicians. The issues addressed in this study are the careers of female and male physicians seven years after graduation and the impact of parenthood on career development. Methods Data reported originates from the fifth assessment (T5) of the prospective SwissMedCareer Study, beginning in 2001 (T1). At T5 in 2009, 579 resid...

  6. Vascular flora in dry-shrub and wet grassland Cerrado seven years after a fire, Federal District, Brasil

    OpenAIRE

    Amaral, Aryanne Gonçalves; Munhoz, Cássia Beatriz Rodrigues; Eugênio, Chesterton Ulysses Orlando; Felfili, Jeanine Maria

    2013-01-01

    ABSTRACT Studies of temporal dynamics for grassland sites report that fire suppression plays a crucial role in floristic changes. The objective of this study was to verify whrther after seven years without fire, communities showed variations in terms of composition, life forms pollination and dispersal syndromes. The first survey (T0) was conducted from September 1999 to October 2000, while the second (T1) took place from August 2006 to August 2007. The floristic results in T1 were compare...

  7. Technical feasibility study on polycarbonate solar panels

    NARCIS (Netherlands)

    Hackmann, M.M.; Meuwissen, M.H.H.; Bots, T.L.; Buijs, J.A.H.M.; Broek, K.M.; Kinderman, R.; Tanck, O.B.F.; Schuurmans, F.M.

    2004-01-01

    This paper describes a technical feasibility study on the application of polycarbonate (PC) plates in a superstrate photovoltaic module design. The lamination process was performed in a conventional laminator apparatus using low temperature curing (100°C) ethylene-vinyl-acetate (EVA) as the potting

  8. Molar incisor hypomineralization and dental caries in six- to seven-year-old Thai children.

    Science.gov (United States)

    Pitiphat, Waranuch; Savisit, Ratchanekorn; Chansamak, Nusara; Subarnbhesaj, Ajiravudh

    2014-01-01

    This study aimed to determine the prevalence of molar incisor hypomineralization (MIH) in Thai children and evaluate the association between MIH and dental caries in the permanent dentition. A cross-sectional study was conducted among six- to seven-year-old participants of a birth cohort study in Khon Kaen, Thailand. MIH was examined by one calibrated dentist using European Academy of Pediatric Dentistry criteria. The association between MIH and caries was determined by logistic regression at subject level, and generalized estimating equations at tooth level. Of 484 children who had at least one erupted permanent first molar, the prevalence of MIH was 20 percent, with no difference between genders. Children with MIH had increased odds of having caries in the permanent dentition compared to those without MIH (odds ratio [OR] equals 4.6; 95 percent confidence interval [CI] equals 2.7 to 7.9). MIH molars had approximately 10 times higher odds of developing caries than non-MIH counterparts (OR equals 9.9; 95 percent CI equals 5.7 to 16.9). Caries risk was higher in the upper molars than in the lower molars. Molar incisor hypomineralization is common and associated with increased risk for dental caries among this group of Thai children.

  9. Cognitive outcomes in prenatal methamphetamine exposed children aged six to seven years.

    Science.gov (United States)

    Kwiatkowski, Maja A; Donald, Kirsten A; Stein, Dan J; Ipser, Jonathan; Thomas, Kevin G F; Roos, Annerine

    2018-01-01

    Methamphetamine use among pregnant women has become a significant problem. Research delineating the cognitive outcomes of prenatal methamphetamine exposure (PME) in early childhood is limited, however. The aim of this study was to examine effects of PME on cognition in six-to-seven-year-old children. PME children (n=23) and unexposed controls (n=22) completed a battery of neurocognitive tests, which included the Kaufman Assessment Battery for Children, Boston Naming Test, Beery Developmental Test of Visual-Motor Integration, and Grooved Pegboard Test. Independent samples t-tests revealed that PME children scored significantly worse than controls on the measures of IQ, learning and memory, confrontation naming, visual-motor integration, and fine motor coordination. Hierarchical regression analyses that included potential confounding sociodemographic, co-exposure and anthropometric variables confirmed that PME impacts negatively on cognitive performance. The study confirms that PME has deleterious effects on cognition in several broad cognitive domains, likely by altering underlying brain circuitry in development. These effects may be particularly pronounced at the time when children enter formal schooling. Extended follow-ups into late childhood might help elucidate the developmental trajectory of cognitive dysfunction in PME, and subsequent effects on everyday functioning. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Marriage duration and divorce: the seven-year itch or a lifelong itch?

    Science.gov (United States)

    Kulu, Hill

    2014-06-01

    Previous studies have shown that the risk of divorce is low during the first months of marriage; it then increases, reaches a maximum, and thereafter begins to decline. Some researchers consider this pattern consistent with the notion of a "seven-year itch," while others argue that the rising-falling pattern of divorce risk is a consequence of misspecification of longitudinal models because of omitted covariates or unobserved heterogeneity. The aim of this study is to investigate the causes of the rising-falling pattern of divorce risk. Using register data from Finland and applying multilevel hazard models, the analysis supports the rising-falling pattern of divorce by marriage duration: the risk of marital dissolution increases, reaches its peak, and then gradually declines. This pattern persists when I control for the sociodemographic characteristics of women and their partners. The inclusion of unobserved heterogeneity in the model leads to some changes in the shape of the baseline risk; however, the rising-falling pattern of the divorce risk persists.

  11. Botulinum toxin type A and cervical dystonia: a seven-year follow-up

    Directory of Open Access Journals (Sweden)

    Carlos Henrique F. Camargo

    2011-10-01

    Full Text Available Most cases of cervical dystonia (CD are idiopathic, and focal injections of botulinum toxin A (BoNT/A are the treatment of choice. The objective of our study was to document the effects of long-term BoNT/A treatment in idiopathic CD patients. Fifty-eight patients with idiopathic CD were recruited from March 2001 to May 2002. Twenty-eight of the subjects were available for reassessment after seven years. During this period, all had received regular treatment with BoNT/A injections. Clinical information about patients and the severity of CD (TWSTRS and VAPS at baseline assessment (2001-2002 and follow-up (2008-2009 was compared. Significant motor improvement was detected based on TWSTRS scale scores, which were used to analyze clinical severity (19.6±6.6 and 17.7±4.8; p<0.05. There was no improvement in the severity of cervical pain (p=0.43. In conclusion, BoNT/A was a safe and effective long-term therapy for CD.

  12. Simulation of natural corrosion by vapor hydration test: seven-year results

    International Nuclear Information System (INIS)

    Luo, J.S.; Ebert, W.L.; Mazer, J.J.; Bates, J.K.

    1996-01-01

    We have investigated the alteration behavior of synthetic basalt and SRL 165 borosilicate waste glasses that had been reacted in water vapor at 70 degrees C for time periods up to seven years. The nature and extent of corrosion of glasses have been determined by characterizing the reacted glass surface with optical microscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy dispersive x-ray spectroscopy (EDS). Alteration in 70 degrees C laboratory tests was compared to that which occurs at 150-200 degrees C and also with Hawaiian basaltic glasses of 480 to 750 year old subaerially altered in nature. Synthetic basalt and waste glasses, both containing about 50 percent wt SiO 2 were found to react with water vapor to form an amorphous hydrated gel that contained small amounts of clay, nearly identical to palagonite layers formed on naturally altered basaltic glass. This result implies that the corrosion reaction in nature can be simulated with a vapor hydration test. These tests also provide a means for measuring the corrosion kinetics, which are difficult to determine by studying natural samples because alteration layers have often spelled off the samples and we have only limited knowledge of the conditions under which alteration occurred

  13. Revisiting SNR Puppis A with Seven Years of Fermi Large Area Telescope Observations

    Energy Technology Data Exchange (ETDEWEB)

    Xin, Yu-Liang; Guo, Xiao-Lei; Liao, Neng-Hui; Yuan, Qiang; Liu, Si-Ming; Wei, Da-Ming, E-mail: yuanq@pmo.ac.cn, E-mail: liusm@pmo.ac.cn, E-mail: dmwei@pmo.ac.cn [Key laboratory of Dark Matter and Space Astronomy, Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China)

    2017-07-10

    Puppis A is a very famous and extensively studied supernova remnant that shows strong evidence of shock-cloud interaction. We reanalyze its GeV γ -ray emission using seven years of Pass 8 data recorded by the Fermi Large Area Telescope. The morphology of the γ -ray emission is more compatible with that of the thermal X-ray and IR emissions than the radio image, which suggests a possible correlation between the gamma-ray-emitting region and dense clouds. The γ -ray spectrum in the energy range of 1–500 GeV shows a break at 7.92 ± 1.91 GeV, with photon indices of 1.81 ± 0.08 below the break and 2.53 ± 0.12 above the break, which can naturally explain the lack of TeV γ -ray emission from Puppis A. The multi-wavelength observations favor a hadronic origin for the γ -ray emission.

  14. THE BASIC AXIAL VARIATION OF SEVEN YEAR OLD Acacia mangium WILLD WOOD

    Directory of Open Access Journals (Sweden)

    Ailton Teixeira do Vale

    2009-09-01

    Full Text Available From a seven year old population of acacia mangium, discs were taken from the trunks of 126 trees in order to study the species’ basic density.  The basic average density (DBM found was between 0.524 + 0.076 g/cm3.  The axial variation for the basic density (Db, explained according to a quadratic model (R2 = 0.83, revealed a reduction tendency of up to half of the trunk’s height, increasing from this point up to the top without reaching the Db’s value for the base.  The linear model was what best explained the relation between the DBM and the Db, obtained at various positions along the trunk.  In fact, this relation  was even more accentuated (R2 = 0.81 at 25% of the trunk’s height.  Thus, in the determining of the species’ DBM through destructive methods, samples taken at 25% of the trunk’s height can be used.  Nevertheless, for non-destructive samples, the height of 25%, may be too much, and so, withdrawing a sample, using an Pressler’s cork bore, for example, may not be feasible.  In this case, withdrawing from the DAP is suggested because the relation at this height is also high (0.78.

  15. SEVEN YEARS (2004-2010 PRECIPITATION DISTRIBUTION IN TRANSYLVANIA (ROMANIA FROM DAILY DATA

    Directory of Open Access Journals (Sweden)

    OTTILIA RUSZ

    2012-11-01

    Full Text Available Seven years (2004-2010 precipitation distribution in Transylvania (Romania from daily data. Daily precipitation amount data from 21 meteorological stations were studied. These stations are located in the following counties: Alba, Brasov, Cluj, Covasna, Harghita, Mures and Sibiu. Factor analysis was applied in order to delimit areas with same precipitation distribution patterns in Transylvania in the period 2004-2010. It was found 3 dominant factors which can explain 67.19 % of variance. All factors are related to local conditions, namely to geographic position, but they are independent from topography. Using factor loadings, 3 maps are presented, which reveals the spatial influence of these 3 factors. For each meteorological station was made a precipitation distribution figure. These figures and the 3 maps were made with Arcmap software using spline with barriers interpolation method. Distribution figures of stations defined by the same factor pattern are similar. The first factor, responsible for less precipitation affects especially the south eastern part of area. The third factor provides the highest amount of rainfall and influence mainly the northern part of region. The south western part of Transylvania is dominated by the second factor which insures the most balanced precipitation pattern.

  16. Description of a seven-year prospective study of human papillomavirus infection and cervical neoplasia among 10 000 women in Guanacaste, Costa Rica Descripción de un estudio prospectivo de siete años sobre la infección por el virus del papiloma humano y el cáncer cervicouterino en 10 000 mujeres de Guanacaste, Costa Rica

    Directory of Open Access Journals (Sweden)

    M. Concepción Bratti

    2004-02-01

    Full Text Available OBJECTIVE:The Guanacaste study ("Guanacaste Project," or GP, was designed to investigate the role of human papillomavirus (HPV infection and its cofactors in the development of cervical neoplasia and to evaluate new cervical cancer screening technologies. The follow-up phase of the GP was designed to study why a small proportion of women infected with HPV develop cervical intraepithelial neoplasia grade 2 (CIN 2, CIN 3, or cancer (these three together are globally referred to as > CIN 2, that is, CIN 2 or worse. The purpose of this article is to describe this prospective study in detail and to present the preliminary findings regarding the incidence of cervical neoplasia. METHODS: A cohort of 10 049 randomly selected women from 18 to 97 years old from Guanacaste, a province in northwestern Costa Rica, was intensively screened in 1993-1994 and then followed up for seven years after being enrolled. A questionnaire for demographic and risk factors was administered, and a pelvic examination was performed on sexually active women at each follow-up visit in order to obtain samples for screening tests and for research purposes. The final diagnosis given at the end of the enrollment phase categorized women into several groups according to the perceived risk of their developing either high-grade precursors of cancer or cancer. These groups were followed up at different intervals according to the risk of developing > CIN 2. The most active follow-up (every 6-12 months was concentrated on the women most likely to develop > CIN 2, based on cytology (n= 492. The remainder of the cohort was followed either annually (n= 2 574 or after five to seven years of passive follow-up (n= 3 926. All women with possibly severe lesions detected by any technique were referred to colposcopy for further evaluation and treatment, and they were also censored from the study. Lesions >CIN 2 served as both the censoring outcome and our surrogate for cancer risk. RESULTS

  17. Sistem Panel Kinerja Untuk Program Studi Sarjana Berbasis BAN PT

    Directory of Open Access Journals (Sweden)

    Agus Prasetyo Utomo

    2016-01-01

    Full Text Available Study program need to do monitoring and continuously measurements of performance to ensure achievement the goals set of its. The process of performance requires monitoring data and information was taken from all parts of the organization. The purpose of this research is to build a panel system performance (performance dashboard that can be used to help measure the performance of undergraduate degree courses based on BAN PT in order of quality assurance in higher education. The results of performance monitoring will be delivered to the parties concerned, efficiently and effectively. Panel System (Dashboard is a tool to present information at a glance. Dashboard inform using Key Performance Indicators (KPI an effective presentation media. KPIs are used in the construction panel system performance of these courses entirely using the instruments of the National Accreditation of Higher Education. The methodology can be applied either on a case study of the development of dashboards to support the efforts of quality assurance courses at the Stikubank University Semarang. This study emphasizes how the application is to provide easy information to Head of study program, Dean of faculty, Rector and Vice Rector of university to the achievement of the quality of undergraduate study program.   Keywords: Performance Dashboard; Key Performance Indicators; Accreditation.

  18. [Using consumer panels in public health observational studies].

    Science.gov (United States)

    Matilla-Santander, Nuria; Fu, Marcela; Ballbè, Montse; Lidón-Moyano, Cristina; Martín-Sánchez, Juan Carlos; Fernández, Esteve; Martínez-Sánchez, José M

    Consumer panels are a market research method useful for gathering information about low-frequency or difficult-access customers. The objective of this field-note is to explain our experience using this method in a cross-sectional public health study on the use of electronic cigarettes. After taking into account other non-probabilistic sampling techniques to obtain a huge sample of electronic-cigarette users (n=600), in the end we decided to use consumer panels (recruiters) because of the relative short duration of the field work and the high representativeness of the sample. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. Low Primary Cesarean Delivery Rates of a Secondary Health Center in a Seven Year-Period

    Directory of Open Access Journals (Sweden)

    Alev Ozer

    2016-04-01

    Full Text Available Aim: To present the indications and primary caesarean section (CS rates of a secondary level hospital. Material and Method: This is a retrospective review of the births recorded at a secondary health center between March 2009 and December 2015. The number of patients with primary CS and repeat CS, total number of births, caesarean indications, and complications were assessed. Results: A total of 6535 live births were recorded during a seven-year-long study period. The mean age of the patients was determined as 26.7 ± 6.0 years (range of age: 15-47 years. Delivery by CS was performed in 20.5% of the total births. Of the caesarean births, 27.8% were primary CS and 72.2% were repeat CS. The mean primary and repeat CS rates during the study period were calculated as 5.7% and 14.8% respectively. The primary CS rate was 8.8% in 2009 and this number decreased to 4.3% in 2015. The most frequently encountered primary CS indications were malpresentation (33.9% followed by fetal distress (23.3% and failure of labour induction (14.8% respectively. No intestinal injury was determined in any patient who underwent caesarean delivery. In the repeat CS group, only one patient had a bladder injury that was successfully repaired. Discussion: The rates of primary caesarean section determined in this study are very low. These low rates can be attributed to several factors such as informing and encouraging patients about vaginal birth, avoiding CS on maternal request, and applying amniotic membrane stripping at term pregnancies.

  20. Panel 3 Studies in Childhood, Chuldren's Culture and Play Culture

    DEFF Research Database (Denmark)

    Toft, Herdis

    A presentation of the collected Works of Flemming Mouritsen as published in "Mouritsen's Metode'. Herdis Toft as Panel Chair introduces the publication and also the panel of 6 researchers discussing his influence in the field....

  1. Ageing tests study on wood-based sandwich panels

    Directory of Open Access Journals (Sweden)

    Mateo, Raquel

    2011-12-01

    Full Text Available Composite lightweight wood panels are being increasingly used in construction in Spain. Their growing use should be accompanied by necessary guarantees based on studies of their properties. As it is prescriptive and in addition to others tests, in the present work is examinated the durability of these panels when exposed to the climatic conditions, a characteristic of great importance for wood products, according to Guide ETAG 016, the current standard defining the ageing tests to be used. However, due to the use class of this material, there are indications that the testing outlined in this Guide is inappropriate for assessing the ageing of wood-based sandwich panels. Alternative tests are here proposed that recreate rather better the real conditions under which these products are used. Covering the samples in a waterproof sheeting permeable to the outward movement of water vapour, which is in fact used in the installation, provided the best procedure for testing these panels.

    Los paneles sándwich de madera son un producto de creciente aplicación en la edificación de nuestro país. Este ascendente uso del material debe estar acompañado de las garantías necesarias avaladas por un estudio previo de sus prestaciones. Como es preceptivo y entre otros, se evalúa su durabilidad frente a las condiciones climatológicas, clave en los productos derivados de la madera, acorde a la normativa actual definida con tal fin, la Guía ETAG 016. Sin embargo, debido a la clase de uso del material, se ha detectado que dicha normativa tal y como está concebida no es capaz de valorar su envejecimiento adecuadamente. En este trabajo se proponen ensayos alternativos al establecido tras exhaustivos análisis que recrean las condiciones reales de uso y más acordes a los productos de madera. Se concluye que la incorporación de una lámina impermeable pero permeable al vapor de agua hacia el exterior, como las utilizadas en el montaje, aportan el mejor

  2. Comparative study on diagonal equivalent methods of masonry infill panel

    Science.gov (United States)

    Amalia, Aniendhita Rizki; Iranata, Data

    2017-06-01

    Infrastructure construction in earthquake prone area needs good design process, including modeling a structure in a correct way to reduce damages caused by an earthquake. Earthquakes cause many damages e.g. collapsed buildings that are dangerous. An incorrect modeling in design process certainly affects the structure's ability in responding to load, i.e. an earthquake load, and it needs to be paid attention to in order to reduce damages and fatalities. A correct modeling considers every aspect that affects the strength of a building, including stiffness of resisting lateral loads caused by an earthquake. Most of structural analyses still use open frame method that does not consider the effect of stiffness of masonry panel to the stiffness and strength of the whole structure. Effect of masonry panel is usually not included in design process, but the presence of this panel greatly affects behavior of the building in responding to an earthquake. In worst case scenario, it can even cause the building to collapse as what has been reported after great earthquakes worldwide. Modeling a structure with masonry panel as consideration can be performed by designing the panel as compression brace or shell element. In designing masonry panel as a compression brace, there are fourteen methods popular to be used by structure designers formulated by Saneinejad-Hobbs, Holmes, Stafford-Smith, Mainstones, Mainstones-Weeks, Bazan-Meli, Liauw Kwan, Paulay and Priestley, FEMA 356, Durani Luo, Hendry, Al-Chaar, Papia and Chen-Iranata. Every method has its own equation and parameters to use, therefore the model of every method was compared to results of experimental test to see which one gives closer values. Moreover, those methods also need to be compared to the open frame to see if they can result values within limits. Experimental test that was used in comparing all methods was taken from Mehrabi's research (Fig. 1), which was a prototype of a frame in a structure with 0.5 scale and the

  3. Speech, language, and hearing function in twins with Alport syndrome: A seven-year retrospective case report

    Directory of Open Access Journals (Sweden)

    Ramesh Kaipa

    2017-06-01

    Full Text Available Alport syndrome is an X-linked syndrome that results in nephritis, renal failure, sensorineural hearing loss, and eye deficits. As a result of sensorineural hearing loss, these individuals are likely to experience difficulties in the area of speech and language. While studies in the past have examined the speech and language characteristics of children with syndromic sensorineural hearing loss, to our knowledge there are no previous studies to have documented the speech and language characteristics of these children on a long-term basis. The current study addresses this limitation by reporting speech, language, hearing, and function of twin brothers with X-linked Alport syndrome across a seven-year period. Information was collected by examining the medical records of the participants as well as through a verbal interview with the participants' guardian. Results revealed that the participants' hearing abilities gradually deteriorated over the seven-year period which affected their speech and language development as well. The kidney function tests revealed significant presence of hematuria (blood in the urine as well as proteinuria (protein in the urine suggesting chronic kidney dysfunction. This longitudinal study demonstrates the functional relationship between the kidneys and the cochlea, although they appear to be independent of one another. As individuals with Alport syndrome exhibit systemic complications, interdisciplinary collaboration is essential among health care providers including audiologists, speech-language pathologists, nephrologists, and ophthalmologist to promote evidence-based practice.

  4. Panel Analysis

    DEFF Research Database (Denmark)

    Brænder, Morten; Andersen, Lotte Bøgh

    2014-01-01

    where panel attrition, the practical and ethical challenges of contacting the same respondents at different points of time may affect response rates negatively. In the article, we present some key distinctions regarding panel data and analyses, and in the subsequent exercises we invite readers to apply...... these concepts on a number of recently published panel studies....

  5. Severe postpartum haemorrhage after vaginal delivery: a statistical process control chart to report seven years of continuous quality improvement.

    Science.gov (United States)

    Dupont, Corinne; Occelli, Pauline; Deneux-Tharaux, Catherine; Touzet, Sandrine; Duclos, Antoine; Bouvier-Colle, Marie-Hélène; Rudigoz, René-Charles; Huissoud, Cyril

    2014-07-01

    Severe postpartum haemorrhage after vaginal delivery: a statistical process control chart to report seven years of continuous quality improvement To use statistical process control charts to describe trends in the prevalence of severe postpartum haemorrhage after vaginal delivery. This assessment was performed 7 years after we initiated a continuous quality improvement programme that began with regular criteria-based audits Observational descriptive study, in a French maternity unit in the Rhône-Alpes region. Quarterly clinical audit meetings to analyse all cases of severe postpartum haemorrhage after vaginal delivery and provide feedback on quality of care with statistical process control tools. The primary outcomes were the prevalence of severe PPH after vaginal delivery and its quarterly monitoring with a control chart. The secondary outcomes included the global quality of care for women with severe postpartum haemorrhage, including the performance rate of each recommended procedure. Differences in these variables between 2005 and 2012 were tested. From 2005 to 2012, the prevalence of severe postpartum haemorrhage declined significantly, from 1.2% to 0.6% of vaginal deliveries (pcontinuous quality improvement efforts began seven years ago and used, among other tools, statistical process control charts. During this period, the prevalence of severe postpartum haemorrhage after vaginal delivery has been reduced by 50%. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  6. Diabetes-related lower-extremity amputation incidence and risk factors: a prospective seven-year study in Costa Rica Incidencia y factores de riesgo de la amputación de extremidades inferiores relacionada con la diabetes: estudio prospectivo de siete años en Costa Rica

    Directory of Open Access Journals (Sweden)

    Adriana Laclé

    2012-09-01

    Full Text Available OBJECTIVE: To analyze the incidence and determinants of lower-extremity amputation (LEA in people with diabetes in a low-income community in Costa Rica. METHODS: Data on LEA incidence were collected during a seven-year follow-up (2001-2007 in a diabetes patient cohort (n = 572. Risk factors were analyzed using the Cox proportional hazards regression model and baseline variables from the year 2000 (socio- demographic characteristics, comorbidity, metabolic control, treatment, and chronic microvascular complications. RESULTS: LEA incidence was 6.02 per 1 000 person-years (8.65 in men and 4.50 in women. Known risk factors (sex, years of diabetes, elevated glycated hemoglobin [HbA1c], retinopathy, insulin therapy, and prior amputation were highly significant. CONCLUSIONS: Those most likely to undergo LEA among Costa Rican diabetic patients were men with 10 or more years of diabetes and average HbA1c > 8% who used insulin and had diabetic retinopathy. Patients on insulin therapy were at greatest risk, especially those with a previous amputation. Diabetic patients with the above-mentioned profile should be considered to be at very high risk of LEA and followed closely by the health care system.OBJETIVO: Analizar la incidencia y los determinantes de la amputación de extremidades inferiores (AEI en personas diabéticas de una comunidad con bajos ingresos de Costa Rica. MÉTODOS: Se recopilaron datos sobre la incidencia de la AEI durante un período de seguimiento de siete años (del 2001 al 2007 en una cohorte de pacientes diabéticos (n = 572. Se analizaron los factores de riesgo usando el modelo de regresión de Cox de riesgos proporcionales y los valores de referencia del año 2000 de las variables (características sociodemográficas, comorbilidad, control metabólico, tratamiento y complicaciones microvasculares crónicas. RESULTADOS: La incidencia de la AEI fue de 6,02 por 1 000 personas-año (8,65 en varones y 4,50 en mujeres. Los factores de

  7. SEVEN-YEAR WILKINSON MICROWAVE ANISOTROPY PROBE (WMAP ) OBSERVATIONS: POWER SPECTRA AND WMAP-DERIVED PARAMETERS

    International Nuclear Information System (INIS)

    Larson, D.; Bennett, C. L.; Gold, B.; Dunkley, J.; Hinshaw, G.; Kogut, A.; Wollack, E.; Komatsu, E.; Nolta, M. R.; Halpern, M.; Hill, R. S.; Odegard, N.; Weiland, J. L.; Jarosik, N.; Page, L.; Limon, M.; Meyer, S. S.; Smith, K. M.; Spergel, D. N.; Tucker, G. S.

    2011-01-01

    The WMAP mission has produced sky maps from seven years of observations at L2. We present the angular power spectra derived from the seven-year maps and discuss the cosmological conclusions that can be inferred from WMAP data alone. With the seven-year data, the temperature (TT) spectrum measurement has a signal-to-noise ratio per multipole that exceeds unity for l m h 2 = 0.1334 +0.0056 -0.0055 , and on the epoch of matter-radiation equality, z eq = 3196 +134 -133 . The temperature-polarization (TE) spectrum is detected in the seven-year data with a significance of 20σ, compared to 13σ with the five-year data. We now detect the second dip in the TE spectrum near l ∼ 450 with high confidence. The TB and EB spectra remain consistent with zero, thus demonstrating low systematic errors and foreground residuals in the data. The low-l EE spectrum, a measure of the optical depth due to reionization, is detected at 5.5σ significance when averaged over l = 2-7: l(l + 1)C EE l /(2π) = 0.074 +0.034 -0.025 μK 2 (68% CL). We now detect the high-l, 24 ≤ l ≤ 800, EE spectrum at over 8σ. The BB spectrum, an important probe of gravitational waves from inflation, remains consistent with zero; when averaged over l = 2-7, l(l + 1)C BB l /(2π) 2 (95% CL). The upper limit on tensor modes from polarization data alone is a factor of two lower with the seven-year data than it was using the five-year data. The data remain consistent with the simple ΛCDM model: the best-fit TT spectrum has an effective χ 2 of 1227 for 1170 degrees of freedom, with a probability to exceed of 9.6%. The allowable volume in the six-dimensional space of ΛCDM parameters has been reduced by a factor of 1.5 relative to the five-year volume, while the ΛCDM model that allows for tensor modes and a running scalar spectral index has a factor of three lower volume when fit to the seven-year data. We test the parameter recovery process for bias and find that the scalar spectral index, n s , is biased

  8. Health Blogging and Social Support: A 3-Year Panel Study.

    Science.gov (United States)

    Keating, David M; Rains, Stephen A

    2015-01-01

    The reported study explored the implications of informal computer-mediated social support for the well-being of individuals coping with illness over the course of 3 years. A panel study was conducted in which respondents--bloggers writing about their experiences living with a health condition--reported on their perceptions of social support and well-being during 2010 and again during 2013. Among respondents who completed both questionnaires (n = 49), increases in support availability from family and friends were related to improvements in bloggers' health self-efficacy as well as improvements in bloggers' loneliness, particularly among those who also experienced increased support availability from blog readers. Increased blog reader support availability was associated with improvements in bloggers' health-related uncertainty. Among respondents who completed the initial questionnaire (N = 121), a survival analysis showed that neither support available from family and friends nor support from blog readers predicted continued health blogging over the 3-year period.

  9. Mnemonic multiples: the case of the columbia panel studies.

    Science.gov (United States)

    Pooley, Jefferson D

    2015-01-01

    This article uses the Bureau of Applied Social Research's mid-century book-length panel studies-The People's Choice (1944), Voting (1954), and Personal Influence (1955)-to identify and illustrate a neglected phenomenon in the remembered history of social science: mnemonic multiples. The article describes the way that the Bureau books, originally published into a post-World War II interdisciplinary social science milieu, have since come to be remembered along distinct disciplinary tracks by sociologists, political scientists, and communication researchers. A contextual analysis of references to the Bureau studies in the flagship journals of the three disciplines, from 1960 through 2011, provides tentative support for the mnemonic multiples concept. © 2014 Wiley Periodicals, Inc.

  10. Results and Implications of Seven Years of the University of Arizona Astronomy Club

    Science.gov (United States)

    Walker-LaFollette, Amanda; Towner, A. P.; Hardegree-Ullman, K.; Brissenden, G.

    2014-01-01

    Participation in an undergraduate astronomy club or organization, be it social, academic, outreach-, or research-oriented, can be extremely beneficial to astronomy students. In this talk, we present the numerical results of the past seven years of University of Arizona Astronomy Club activities, particularly those relating to published papers, poster presentations, attendance at AAS meetings, and retention within the major. We also discuss less-quantifiable results, such as social, academic, and emotional support for club members. Finally, we highlight the efforts being performed by undergraduates at institutions all around the country, as presented in this Session.

  11. Experimental studies on multicellular GFRP bridge deck panels ...

    Indian Academy of Sciences (India)

    M P MUTHURAJ

    2017-11-20

    Nov 20, 2017 ... cellular glass fibre reinforced polymer (GFRP) composite bridge deck panels under static and fatigue loading. Various ... deck panels of size 1250 mm 9 333 mm 9 150 mm (l 9 b 9 d) were fabricated by hand lay-up process and tested for static .... Carbon dioxide emission is one of the important aspects to.

  12. Experimental study of hydronic panels system and its environment

    Energy Technology Data Exchange (ETDEWEB)

    Diaz, Nestor Fonseca [University of Liege Belgium, Thermodynamics Laboratory, Campus du Sart Tilman, Bat: B49 - P33, B-4000 Liege (Belgium); Universidad Tecnologica de Pereira, Facultad de Ingenieria Mecanica (Colombia)

    2011-01-15

    An experimental analysis of hydronic cooling or heating ceiling panels coupled to the building is present in this investigation as a part of the commissioning study of this system. Two test chambers are adapted in a way to reproduce the interaction of the system to the building (windows, internal thermal loads distribution, building structure and ventilation). A series of experimental tests were performed in which the main objective is to observe the influence of parameters such as the water mass flow rate, supply water temperature, thermal load distribution, window and ventilation system effects on the hydronic ceiling capacity and comfort conditions. Test results show that the influence of asymmetric surfaces temperatures inside the room, especially the window effect is not negligible. Then, it is clear that the cooling hydronic ceiling must be evaluated coupled to the building systems and structure. (author)

  13. Experimental study of hydronic panels system and its environment

    Energy Technology Data Exchange (ETDEWEB)

    Fonseca Diaz, Nestor, E-mail: nestorfonseca5@hotmail.co [University of Liege Belgium, Thermodynamics Laboratory, Campus du Sart Tilman, Bat: B49 - P33, B-4000 Liege (Belgium); Universidad Tecnologica de Pereira, Facultad de Ingenieria Mecanica (Colombia)

    2011-01-15

    An experimental analysis of hydronic cooling or heating ceiling panels coupled to the building is present in this investigation as a part of the commissioning study of this system. Two test chambers are adapted in a way to reproduce the interaction of the system to the building (windows, internal thermal loads distribution, building structure and ventilation). A series of experimental tests were performed in which the main objective is to observe the influence of parameters such as the water mass flow rate, supply water temperature, thermal load distribution, window and ventilation system effects on the hydronic ceiling capacity and comfort conditions. Test results show that the influence of asymmetric surfaces temperatures inside the room, especially the window effect is not negligible. Then, it is clear that the cooling hydronic ceiling must be evaluated coupled to the building systems and structure.

  14. Experimental study of efficiency of solar panel by phase change material cooling

    Science.gov (United States)

    Wei, Nicholas Tan Jian; Nan, Wong Jian; Guiping, Cheng

    2017-07-01

    The dependence of efficiency of photovoltaic panels on their temperature during operation is a major concern for developers and users. In this paper, a phase change material (PCM) cooling system was designed for a 60W mono-crystalline solar panel. Tealights candle was selected as the cooling medium. The solar irradiance was recorded using Kipp & Zonen CMP3 pyranometer and Meteon data logger. Temperature distribution on the surface of solar panel, output voltage and output current of solar panel were measured. The average irradiance throughout data collection was found to be 705W/m2 and highest irradiance was 1100 W/m2. The average solar panel temperature was 43.6°C and a maximum temperature of 53°C was at the center of solar panel. Results showed that average power output and efficiency of the solar panel were 44.4W and 15%, respectively. It was found that the higher the solar irradiance, the lower the efficiency of solar panel and the higher the temperature and power output of solar panel. This is due to the fact that high irradiance results in high power input and high solar panel temperature. But high PV panel temperature reduces its power output. Therefore, the increase of power input outweighs that of power output, which leads to the decrease of efficiency of solar panel with the increase of solar irradiance. Compared with solar panel without cooling, the power output and efficiency of solar panel did not increase with PCM cooling. It indicates that Tealights candle as PCM cooling is not efficient in improving the efficiency of solar panel in this study.

  15. Ballistic study of Tensylon®–based panels

    Directory of Open Access Journals (Sweden)

    L-C. Alil

    2018-06-01

    Full Text Available Ballistic protection is a matter of interest requested by civilian as well as military needs. The last decade has witnessed an increase in the use of light weight and efficient armour systems. These panels may be used for body protection as well as light vehicle protection against small calibres or to enhance the protection level of heavier vehicles with decreasing or maintaining their weight penalty. Ultra high molecular weight polyethylene is a material of interest for light weight armour applications. The authors designed panels made of hot–pressed Tensylon® in different configurations with thin steel sheets as a backing and shield protection. Comparison of their ballistic performance to the theory predictions reveals the improved ballistic response of the panels. In addition, a non–pressed Tensylon® panel has been tested in order to facilitate the observations of the failure mechanisms inside the panels. Even if not suitable for practical use, such non–pressed panels clearly reveal the dynamic processes at micro–scale that occur during the impact. The failure mechanisms of the material under bullet penetration are discussed based on photography, optical microscopy and scanning electron microscopy. The supposed effects of the panel pressing are discussed based on the observed difference between pressed and non–pressed structures ballistic response.

  16. Influence of gap and overlap paradigms on saccade latencies and vergence eye movements in seven-year-old children.

    Science.gov (United States)

    Bucci, Maria Pia; Pouvreau, Nathalie; Yang, Qing; Kapoula, Zoï

    2005-07-01

    The latency of eye movements is influenced by the fixation task; when the fixation stimulus is switched off before the target presentation (gap paradigm) the latency becomes short and express movements occur. In contrast, when the fixation stimulus remains on when the target appears (overlap paradigm), eye movement latency is longer. Several previous studies have shown increased rates of express saccades in children; however the presence of an express type of latency for vergence and combined movements in children has never been explored. The present study examines the effects of the gap and the overlap paradigms on horizontal saccades at far (150 cm) and at close (20 cm) viewing distances, on vergence along the median plane, and on saccades combined with convergence or divergence in 15 normal seven-year-old children. The results show that the gap paradigm produced shorter latency for all eye movements than the overlap paradigm, but the difference was only significant for saccades at close viewing distances, for divergence (pure and combined), and for saccades combined with vergence. The gap paradigm produced significantly higher rates of express latencies for saccades at close viewing distances, for divergence, and for saccades combined with divergence; in contrast, the frequencies of express latencies for saccades at far viewing distances and for convergence (pure or combined) were similar in the gap and the overlap paradigms. Interestingly, the rate of anticipatory latencies (gap paradigm. Our collective findings suggest that the initiation of saccades at close viewing distances and of divergence is more reflexive, particularly in the gap paradigm. The finding of frequent anticipatory divergence that occurs at similar rates for seven-year-old children (this study) and for adults (Coubard et al., 2004, Exp Brain Res 154:368-381) indicates that predictive initiation of divergence is dominant.

  17. SEVEN-YEAR WILKINSON MICROWAVE ANISOTROPY PROBE (WMAP ) OBSERVATIONS: COSMOLOGICAL INTERPRETATION

    International Nuclear Information System (INIS)

    Komatsu, E.; Smith, K. M.; Spergel, D. N.; Dunkley, J.; Bennett, C. L.; Gold, B.; Larson, D.; Hinshaw, G.; Kogut, A.; Wollack, E.; Jarosik, N.; Page, L.; Nolta, M. R.; Halpern, M.; Hill, R. S.; Odegard, N.; Weiland, J. L.; Limon, M.; Meyer, S. S.; Tucker, G. S.

    2011-01-01

    The combination of seven-year data from WMAP and improved astrophysical data rigorously tests the standard cosmological model and places new constraints on its basic parameters and extensions. By combining the WMAP data with the latest distance measurements from the baryon acoustic oscillations (BAO) in the distribution of galaxies and the Hubble constant (H 0 ) measurement, we determine the parameters of the simplest six-parameter ΛCDM model. The power-law index of the primordial power spectrum is n s = 0.968 ± 0.012 (68% CL) for this data combination, a measurement that excludes the Harrison-Zel'dovich-Peebles spectrum by 99.5% CL. The other parameters, including those beyond the minimal set, are also consistent with, and improved from, the five-year results. We find no convincing deviations from the minimal model. The seven-year temperature power spectrum gives a better determination of the third acoustic peak, which results in a better determination of the redshift of the matter-radiation equality epoch. Notable examples of improved parameters are the total mass of neutrinos, ΣM ν eff = 4.34 +0.86 -0.88 (68% CL), which benefit from better determinations of the third peak and H 0 . The limit on a constant dark energy equation of state parameter from WMAP+BAO+H 0 , without high-redshift Type Ia supernovae, is w = -1.10 ± 0.14 (68% CL). We detect the effect of primordial helium on the temperature power spectrum and provide a new test of big bang nucleosynthesis by measuring Y p = 0.326 ± 0.075 (68% CL). We detect, and show on the map for the first time, the tangential and radial polarization patterns around hot and cold spots of temperature fluctuations, an important test of physical processes at z = 1090 and the dominance of adiabatic scalar fluctuations. The seven-year polarization data have significantly improved: we now detect the temperature-E-mode polarization cross power spectrum at 21σ, compared with 13σ from the five-year data. With the seven-year

  18. Utility/manufacturers robot user group: a status overview during its first seven years

    International Nuclear Information System (INIS)

    Meieran, H.B.; Roman, H.T.

    1993-01-01

    In the 14 years since the Three Mile Island Accident, many utility organizations have become active in the evaluation testing demonstration of robotic devices. Although these devices have been used primarily in nuclear power plants, they have also found application in fossil-fuelled and hydro-electric power plants and in tasks involving the transmission and distribution of electrical energy, water, and gas. This increasing interest in robotics has promoted the formation of the Utility/Manufacturers Robots Users Group (U/M RUG) in 1986, an organization that fosters the application of cost-effective application of robotic devices within the various utility organizations. Although U/M RUG has been operating for the past seven years, information presented in this paper will concentrate upon the history, efforts, and activities of this organization generated during the last 4 years since U/M RUG was first introduced in 1988. (author)

  19. Seven years of recording from monkey cortex with a chronically implanted multiple microelectrode

    Directory of Open Access Journals (Sweden)

    Jürgen Krüger

    2010-05-01

    Full Text Available A brush of 64 microwires was chronically implanted in the ventral premotor cortex of a macaque monkey. Contrary to common approaches, the wires were inserted from the white matter side. This approach, by avoiding mechanical pressure on the dura and pia mater during penetration, disturbed only minimally the cortical recording site. With this approach isolated potentials and multiunit activity were recorded for more than seven years in about one third of electrodes. The indirect insertion method also provided an excellent stability within each recording session, and in some cases even allowed recording from the same neurons for several years. Histological examination of the implanted brain region shows only a very marginal damage the recording area. Advantages and problems related to long-term recording are discussed.

  20. Peritoneal mesothelioma in a woman who has survived for seven years: a case report

    Directory of Open Access Journals (Sweden)

    Pourgholami Mohammad H

    2011-01-01

    Full Text Available Abstract Introduction Malignant peritoneal mesothelioma is a rare cancer with poor patient survival. Female gender has been identified as a positive prognostic factor. Recently, it has been suggested that the expression of estrogen receptor β in malignant mesothelioma leads to tumor suppression and a better prognosis. Case presentation We report the case of a 48-year-old Caucasian woman who is alive and disease-free seven years after the initial diagnosis and treatment of malignant peritoneal mesothelioma. Conclusion This patient's long survival may be attributable to a combination of factors, including minimal disease, complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy plus the estrogen receptor β positivity of the tumor.

  1. NGC seven year statement for the years 1996/7 to 2002/03

    International Nuclear Information System (INIS)

    1996-04-01

    This Seven Year Statement by the National Grid Company (NGC) in the United Kingdom is intended to assist existing or prospective customers to assess the opportunities in the electricity market for making new or additional use of the power transmission system. The wide range of information provided is derived largely from data provided by customers. It combines user expectation for future generation and demand with NGC's forecasts of the development of the transmission system. NGC is not able to report on prospective developments which have not yet reached the formal commitment stage, but the impact of various alternative scenarios is considered. Recent developments in the electricity market which could affect the future position are discussed. (UK)

  2. Study of the cracking of sandwich panels of plasterboard and rockwool

    OpenAIRE

    Alonso, J. A.; Reyes, E.; Gálvez, J. C.

    2013-01-01

    This paper presents the study of plasterboard and rockwool sandwich panels cracking under flexural loading. These panels are usually used to perform interior partition walls and they frequently show cracking pathology due to excessive deflexion of the slabs. There are currently no reliable simulation models and experimental data for the study of this problem. This paper presents the results of an experimental campaign aimed to characterize the fracture behaviour of sandwich panels and their i...

  3. Numerical analysis and parametric studies of the buckling of composite orthotropic compression and shear panels

    Science.gov (United States)

    Housner, J. M.; Stein, M.

    1975-01-01

    A computer program is presented which was developed for the combined compression and shear of stiffened variable thickness orthotropic composite panels on discrete springs: boundary conditions are general and include elastic boundary restraints. Buckling solutions are obtained by using a newly developed trigonometric finite difference procedure which improves the solution convergence rate over conventional finite difference methods. The classical general shear buckling results which exist only for simply supported panels over a limited range of orthotropic properties, were extended to the complete range of these properties for simply supported panels and, in addition, to the complete range of orthotropic properties for clamped panels. The program was also applied to parametric studies which examine the effect of filament orientation upon the buckling of graphite-epoxy panels. These studies included an examination of the filament orientations which yield maximum shear or compressive buckling strength for panels having all four edges simply supported or clamped over a wide range of aspect ratios. Panels with such orientations had higher buckling loads than comparable, equal weight, thin skinned aluminum panels. Also included among the parameter studies were examinations of combined axial compression and shear buckling and examinations of panels with rotational elastic edge restraints.

  4. First-Year Maternal Employment and Child Development in the First Seven Years.

    Science.gov (United States)

    Brooks-Gunn, Jeanne; Han, Wen-Jui; Waldfogel, Jane

    2010-08-01

    Using data from the first 2 phases of the NICHD Study of Early Child Care, we examine the links between maternal employment in the first 12 months of life and cognitive, social, and emotional outcomes for children at age 3, age 4½, and first grade. Drawing on theory and prior research from developmental psychology as well as economics and sociology, we address three main questions. First, what associations exist between first-year maternal employment and cognitive, social, and emotional outcomes for children over the first seven years of life? Second, to what extent do any such associations vary by the child's gender and temperament, or the mother's occupation? Third, to what extent do mother's earnings, the home environment (maternal depressive symptoms, sensitivity, and HOME scores), and the type and quality of child care mediate or offset any associations between first-year employment and child outcomes, and what is the net effect of first-year maternal employment once these factors are taken into account? We compare families in which mothers worked full time (55%), part time (23%), or did not work (22%) in the first year for non-Hispanic white children (N=900) and for African-American children (N=113). Comparisons are also made taking into account the timing of mothers' employment within the first year. A rich set of control variables are included. OLS and SEM analyses are constructed. With regard to cognitive outcomes, first, we find that full-time maternal employment in the first 12 months of life (but not part-time employment) is associated with significantly lower scores on some, but not all, measures of cognitive development at age 3, 4 ½, and first grade for non-Hispanic white children, but with no significant associations for the small sample of African-American children Part-time employment in the first year is associated with higher scores than full-time employment for some measures. Employment in the second and third year of life is not associated

  5. Seven-Year Multi-Colour Optical Monitoring of BL Lacertae Object ...

    Indian Academy of Sciences (India)

    (JD 2,455,626). 3.2 Colour behaviours. The colour behaviours of S5 0716 +714 were investigated on both long and short timescales. Figure 3 gives overall colour-magnitude diagram (CMD) for the data before and after 2006 December. Although the data points are quite scattered, there are clear BWB trends on both panels.

  6. Experimental studies on multicellular GFRP bridge deck panels ...

    Indian Academy of Sciences (India)

    This paper presents the experimental investigations carried out on hand lay-up prototype multicellular glass fibre reinforced polymer (GFRP) composite bridge deck panels under static and fatigue loading. Various sustainability aspects with regard to GFRP structural members were discussed. The aspects include(i) social ...

  7. Experimental studies on multicellular GFRP bridge deck panels ...

    Indian Academy of Sciences (India)

    M P MUTHURAJ

    2017-11-20

    Nov 20, 2017 ... design of a new bridge deck panel made of GFRP. Zhu and. Lopez [9] ... than that for a concrete deck, as demonstrated by Daniel. [18] and Resins et al ... waste prevention or reduction;. • re-use;. • material recycling;. • energy recovery;. • landfill/disposal. FRP decks are generally prefabricated by various effi-.

  8. A Power Case Study for Monocrystalline and Polycrystalline Solar Panels in Bursa City, Turkey

    Directory of Open Access Journals (Sweden)

    Ayşegül Taşçıoğlu

    2016-01-01

    Full Text Available It was intended to reveal the time dependent power generation under different loads for two different solar panels under the conditions of Bursa province in between August 19 and 25, 2014. The testing sets include solar panels, inverter, multimeter, accumulator, regulator, pyranometer, pyrheliometer, temperature sensor, and datalogger. The efficiency of monocrystalline and polycrystalline solar panels was calculated depending on the climatic data’s measurements. As the result of the study, the average performances of monocrystalline and polycrystalline panels are 42.06 and 39.80 Wh, respectively. It was seen that 87.14 W instantaneous power could be obtained from monocrystalline solar panel and that 80.17 W instantaneous power could be obtained from polycrystalline solar panel under maximum total radiation (1001.13 W/m2. Within this frame, it was determined that monocrystalline solar panel is able to operate more efficiently under the conditions of Bursa compared to polycrystalline solar panel. When the multivariate correlations coefficients were examined statistically, a significant relationship in positive direction was detected between total and direct radiation and ambient temperature on energy generation from monocrystalline and polycrystalline panel.

  9. Surgical complications of radical retropubic prostatectomy: A single institutional experience of seven years

    Directory of Open Access Journals (Sweden)

    Neeraj K Goyal

    2007-01-01

    Full Text Available Aim: To determine the surgical complications of open retropubic radical prostatectomy. Materials and Methods: Fifty-nine cases of localized prostate cancer underwent retropubic radical prostatectomy in our department in the last seven years. Standard technique of open retropubic radical prostatectomy as described by Walsh was used. During follow-up cancer control and quality of life indices (potency and urinary continence were noted. Result: Postoperative recovery of all patients except one was excellent. This patient required cardio-respiratory support and nine units of blood transfusion. Forty-nine out of 52 patients were continent, two had stress incontinence and one was totally incontinent at one year. Bladder neck contracture was present in eight out of 52 patients at one year. Forty-five patients were impotent at one year with or without oral tablet sildenafil. Cancer control was present in 45 out of 52 cases. Seven cases had biochemical failure at one year. Conclusion: Though retropubic radical prostatectomy is the standard treatment for early prostate cancer it is not without complications. It has a steep learning curve. More number of cases and refinement in technique is required to achieve world-class results.

  10. Constraints on Galactic Neutrino Emission with Seven Years of IceCube Data

    Science.gov (United States)

    Aartsen, M. G.; Ackermann, M.; Adams, J.; Aguilar, J. A.; Ahlers, M.; Ahrens, M.; Samarai, I. Al; Altmann, D.; Andeen, K.; Anderson, T.; Ansseau, I.; Anton, G.; Argüelles, C.; Auffenberg, J.; Axani, S.; Bagherpour, H.; Bai, X.; Barron, J. P.; Barwick, S. W.; Baum, V.; Bay, R.; Beatty, J. J.; Becker Tjus, J.; Becker, K.-H.; BenZvi, S.; Berley, D.; Bernardini, E.; Besson, D. Z.; Binder, G.; Bindig, D.; Blaufuss, E.; Blot, S.; Bohm, C.; Börner, M.; Bos, F.; Bose, D.; Böser, S.; Botner, O.; Bourbeau, J.; Bradascio, F.; Braun, J.; Brayeur, L.; Brenzke, M.; Bretz, H.-P.; Bron, S.; Burgman, A.; Carver, T.; Casey, J.; Casier, M.; Cheung, E.; Chirkin, D.; Christov, A.; Clark, K.; Classen, L.; Coenders, S.; Collin, G. H.; Conrad, J. M.; Cowen, D. F.; Cross, R.; Day, M.; de André, J. P. A. M.; De Clercq, C.; DeLaunay, J. J.; Dembinski, H.; De Ridder, S.; Desiati, P.; de Vries, K. D.; de Wasseige, G.; de With, M.; DeYoung, T.; Díaz-Vélez, J. C.; di Lorenzo, V.; Dujmovic, H.; Dumm, J. P.; Dunkman, M.; Eberhardt, B.; Ehrhardt, T.; Eichmann, B.; Eller, P.; Evenson, P. A.; Fahey, S.; Fazely, A. R.; Felde, J.; Filimonov, K.; Finley, C.; Flis, S.; Franckowiak, A.; Friedman, E.; Fuchs, T.; Gaisser, T. K.; Gallagher, J.; Gerhardt, L.; Ghorbani, K.; Giang, W.; Glauch, T.; Glüsenkamp, T.; Goldschmidt, A.; Gonzalez, J. G.; Grant, D.; Griffith, Z.; Haack, C.; Hallgren, A.; Halzen, F.; Hanson, K.; Hebecker, D.; Heereman, D.; Helbing, K.; Hellauer, R.; Hickford, S.; Hignight, J.; Hill, G. C.; Hoffman, K. D.; Hoffmann, R.; Hokanson-Fasig, B.; Hoshina, K.; Huang, F.; Huber, M.; Hultqvist, K.; In, S.; Ishihara, A.; Jacobi, E.; Japaridze, G. S.; Jeong, M.; Jero, K.; Jones, B. J. P.; Kalacynski, P.; Kang, W.; Kappes, A.; Karg, T.; Karle, A.; Katz, U.; Kauer, M.; Keivani, A.; Kelley, J. L.; Kheirandish, A.; Kim, J.; Kim, M.; Kintscher, T.; Kiryluk, J.; Kittler, T.; Klein, S. R.; Kohnen, G.; Koirala, R.; Kolanoski, H.; Köpke, L.; Kopper, C.; Kopper, S.; Koschinsky, J. P.; Koskinen, D. J.; Kowalski, M.; Krings, K.; Kroll, M.; Krückl, G.; Kunnen, J.; Kunwar, S.; Kurahashi, N.; Kuwabara, T.; Kyriacou, A.; Labare, M.; Lanfranchi, J. L.; Larson, M. J.; Lauber, F.; Lennarz, D.; Lesiak-Bzdak, M.; Leuermann, M.; Liu, Q. R.; Lu, L.; Lünemann, J.; Luszczak, W.; Madsen, J.; Maggi, G.; Mahn, K. B. M.; Mancina, S.; Maruyama, R.; Mase, K.; Maunu, R.; McNally, F.; Meagher, K.; Medici, M.; Meier, M.; Menne, T.; Merino, G.; Meures, T.; Miarecki, S.; Micallef, J.; Momenté, G.; Montaruli, T.; Moore, R. W.; Moulai, M.; Nahnhauer, R.; Nakarmi, P.; Naumann, U.; Neer, G.; Niederhausen, H.; Nowicki, S. C.; Nygren, D. R.; Obertacke Pollmann, A.; Olivas, A.; O'Murchadha, A.; Palczewski, T.; Pandya, H.; Pankova, D. V.; Peiffer, P.; Pepper, J. A.; Pérez de los Heros, C.; Pieloth, D.; Pinat, E.; Plum, M.; Price, P. B.; Przybylski, G. T.; Raab, C.; Rädel, L.; Rameez, M.; Rawlins, K.; Reimann, R.; Relethford, B.; Relich, M.; Resconi, E.; Rhode, W.; Richman, M.; Robertson, S.; Rongen, M.; Rott, C.; Ruhe, T.; Ryckbosch, D.; Rysewyk, D.; Sälzer, T.; Sanchez Herrera, S. E.; Sandrock, A.; Sandroos, J.; Sarkar, S.; Sarkar, S.; Satalecka, K.; Schlunder, P.; Schmidt, T.; Schneider, A.; Schoenen, S.; Schöneberg, S.; Schumacher, L.; Seckel, D.; Seunarine, S.; Soldin, D.; Song, M.; Spiczak, G. M.; Spiering, C.; Stachurska, J.; Stanev, T.; Stasik, A.; Stettner, J.; Steuer, A.; Stezelberger, T.; Stokstad, R. G.; Stößl, A.; Strotjohann, N. L.; Sullivan, G. W.; Sutherland, M.; Taboada, I.; Tatar, J.; Tenholt, F.; Ter-Antonyan, S.; Terliuk, A.; Tešić, G.; Tilav, S.; Toale, P. A.; Tobin, M. N.; Toscano, S.; Tosi, D.; Tselengidou, M.; Tung, C. F.; Turcati, A.; Turley, C. F.; Ty, B.; Unger, E.; Usner, M.; Vandenbroucke, J.; Van Driessche, W.; van Eijndhoven, N.; Vanheule, S.; van Santen, J.; Vehring, M.; Vogel, E.; Vraeghe, M.; Walck, C.; Wallace, A.; Wallraff, M.; Wandler, F. D.; Wandkowsky, N.; Waza, A.; Weaver, C.; Weiss, M. J.; Wendt, C.; Westerhoff, S.; Whelan, B. J.; Wickmann, S.; Wiebe, K.; Wiebusch, C. H.; Wille, L.; Williams, D. R.; Wills, L.; Wolf, M.; Wood, J.; Wood, T. R.; Woolsey, E.; Woschnagg, K.; Xu, D. L.; Xu, X. W.; Xu, Y.; Yanez, J. P.; Yodh, G.; Yoshida, S.; Yuan, T.; Zoll, M.; IceCube Collaboration

    2017-11-01

    The origins of high-energy astrophysical neutrinos remain a mystery despite extensive searches for their sources. We present constraints from seven years of IceCube Neutrino Observatory muon data on the neutrino flux coming from the Galactic plane. This flux is expected from cosmic-ray interactions with the interstellar medium or near localized sources. Two methods were developed to test for a spatially extended flux from the entire plane, both of which are maximum likelihood fits but with different signal and background modeling techniques. We consider three templates for Galactic neutrino emission based primarily on gamma-ray observations and models that cover a wide range of possibilities. Based on these templates and in the benchmark case of an unbroken {E}-2.5 power-law energy spectrum, we set 90% confidence level upper limits, constraining the possible Galactic contribution to the diffuse neutrino flux to be relatively small, less than 14% of the flux reported in Aartsen et al. above 1 TeV. A stacking method is also used to test catalogs of known high-energy Galactic gamma-ray sources.

  11. Woman in Intercollegiate Sport: A Longitudinal, National Study. Thirty-Seven Year Update, 1977-2014

    Science.gov (United States)

    Acosta, R. Vivian; Carpenter, Linda Jean

    2014-01-01

    In 1970, prior to the 1972 enactment of Title IX, there were only 2.5 women's teams per school and a total of only about 16,000 female intercollegiate athletes. In 1977/1978, the academic year preceding the mandatory compliance date for Title IX, the number of varsity sports for women had grown to 5.61 per school. A decade later, in 1988, the…

  12. Seven-year prospective clinical study on zirconia-based single crowns and fixed dental prostheses.

    Science.gov (United States)

    Tartaglia, Gianluca M; Sidoti, Ernesto; Sforza, Chiarella

    2015-06-01

    Zirconia-based prostheses are used for esthetic crown and fixed restorations, but follow-ups are still limited. The authors evaluated the 7-year clinical results of 303 zirconia core restorations, performed in a general dental private practice. Clinical events (fracture and loss of retention, gingivitis, tenderness, excess cement, and temporary pain) were recorded in 303 zirconia core restorations positioned in 88 patients. Kaplan-Meier survival probability estimates were computed for failures (needed the replacement or removal of the prosthesis) and complications (resolved without replacing the prosthesis). One hundred and fifty single crowns (130 tooth-supported, 20 implant-supported) and 153 multiple units up to 6 elements (49 tooth-supported, 104 implant-supported) were followed-up for 7 years in 88 patients (40 men, 48 women), aged 35-89 years (mean 57). During the follow-up period, there were no complications for 287 (95 %) of the restorations. Sixteen restorations/abutment teeth (5 %) had some complication: extraction of abutment tooth (7, 2 %); caries (2, 1 %), porcelain veneer fracture (3, 1 %), loss of retention (4, 1 %). Nine (3 %) restorations were recorded as failures. The overall 7-year survival probability estimate for failures was 0.966 (95 % confidence limits, 0.932 and 0.983), for complications was 0.976 (95 % confidence limits 0.947 and 0.989), with a cumulative survival rate of 94.7 %. Within the analyzed follow-up, zirconia core restorations appear a good clinical solution, with favorable functional properties. All ceramic restorations can be successfully used for both single-and multiple-unit prostheses, either teeth or implants supported.

  13. Does Scale Really Matter? Ultra-Large-Scale Systems Seven Years after the Study

    Science.gov (United States)

    2013-05-24

    Holger Giese, Paola Inverardi, Jeff Magee, Jesper Andersson , Basil Becker et al. Software Engineering for Self-adaptive Systems: A Research Roadmap...IEEE, pp. 1-7. IEEE, 2008. Zhang, Charles . "FlexSync: An Aspect-oriented Approach to Java Synchronization." In Proceedings of the 31st International

  14. Seven-year follow-up of patients diagnosed with atypical odontalgia: a prospective study.

    Science.gov (United States)

    Pigg, Maria; Svensson, Peter; Drangsholt, Mark; List, Thomas

    2013-01-01

    To examine the long-term prognosis of 46 previously examined atypical odontalgia (AO) patients. In 2002 and 2009, AO patients completed validated instruments measuring pain characteristics (pain frequency and intensity), physical functioning (Graded Chronic Pain Severity, GCPS) and emotional functioning (Symptoms Checklist, SCL-90R). The main outcome was global improvement. Baseline data on quantitative somatosensory testing and responsiveness to lidocaine injection were available for a subgroup of patients. Paired tests compared baseline and follow-up data, and logistic regression explored the possible prognostic value of baseline data. Data from 37 patients (80%) were obtained. Thirteen patients (35%; 95% confidence intervals [CI] 20.2%-52.5%) rated their overall pain status as significantly improved, 22 (60%; 95% CI 42.1%-75.3%) as a little improved or unchanged, and two patients (5%; 95% CI 0.7%-18.2%) as worse. Five patients (14%; 95% CI 4.5%-28.8%) were pain-free, indicated by a characteristic pain intensity score of 0. Average pain intensity decreased (from 5.7 ± 2.0 to 3.5 ± 2.4; P < .001). Pain frequency (P < .001) and GCPS (P < .001) also decreased, whereas SCL-90R scores remained unchanged and 26 of the 37 patients reported ongoing treatment. Low baseline pain intensity was the only factor predictive of favorable outcome. A third of the AO patients improved considerably over time, but for many of the patients, AO was a persistent and treatment-resistant condition.

  15. A post hoc study on gene panel analysis for the diagnosis of dystonia.

    Science.gov (United States)

    van Egmond, Martje E; Lugtenberg, Coen H A; Brouwer, Oebele F; Contarino, Maria Fiorella; Fung, Victor S C; Heiner-Fokkema, M Rebecca; van Hilten, Jacobus J; van der Hout, Annemarie H; Peall, Kathryn J; Sinke, Richard J; Roze, Emmanuel; Verschuuren-Bemelmans, Corien C; Willemsen, Michel A; Wolf, Nicole I; Tijssen, Marina A; de Koning, Tom J

    2017-04-01

    Genetic disorders causing dystonia show great heterogeneity. Recent studies have suggested that next-generation sequencing techniques such as gene panel analysis can be effective in diagnosing heterogeneous conditions. The objective of this study was to investigate whether dystonia patients with a suspected genetic cause could benefit from the use of gene panel analysis. In this post hoc study, we describe gene panel analysis results of 61 dystonia patients (mean age, 31 years; 72% young onset) in our tertiary referral center. The panel covered 94 dystonia-associated genes. As comparison with a historic cohort was not possible because of the rapidly growing list of dystonia genes, we compared the diagnostic workup with and without gene panel analysis in the same patients. The workup without gene panel analysis (control group) included theoretical diagnostic strategies formulated by independent experts in the field, based on detailed case descriptions. The primary outcome measure was diagnostic yield; secondary measures were cost and duration of diagnostic workup. Workup with gene panel analysis led to a confirmed molecular diagnosis in 14.8%, versus 7.4% in the control group (P = 0.096). In the control group, on average 3 genes/case were requested. The mean costs were lower in the gene panel analysis group (€1822/case) than in the controls (€2660/case). The duration of the workup was considerably shorter with gene panel analysis (28 vs 102 days). Gene panel analysis facilitates molecular diagnosis in complex cases of dystonia, with a good diagnostic yield (14.8%), a quicker diagnostic workup, and lower costs, representing a major improvement for patients and their families. © 2016 International Parkinson and Movement Disorder Society. © 2017 International Parkinson and Movement Disorder Society.

  16. Study of the cracking of sandwich panels of plasterboard and rockwool

    Directory of Open Access Journals (Sweden)

    Alonso, J. A.

    2013-09-01

    Full Text Available This paper presents the study of plasterboard and rockwool sandwich panels cracking under flexural loading. These panels are usually used to perform interior partition walls and they frequently show cracking pathology due to excessive deflexion of the slabs. There are currently no reliable simulation models and experimental data for the study of this problem. This paper presents the results of an experimental campaign aimed to characterize the fracture behaviour of sandwich panels and their individual components. In addition, the paper presents a cohesive model with embedded crack to simulate the fracture behaviour of the panel. Finally we present the results of tests for mixed mode fracture (tensile / shear commercial panels and their behaviour is reproduced with the cohesive model proposed, yielding a good fit.Este artículo presenta el estudio de la rotura de paneles sándwich de yeso laminado y lana de roca bajo solicitaciones de flexo-tracción dentro de su plano. Estos paneles se emplean para conformar tabiques interiores de edificación y con frecuencia se fisuran por flechas excesivas en los forjados. Actualmente no hay modelos de cálculo fiables ni datos experimentales que permitan estudiar este problema. Este trabajo presenta los resultados de una campaña experimental encaminada a caracterizar el comportamiento en rotura de los paneles sándwich y de sus componentes individuales. Además, se presenta un modelo cohesivo con fisura embebida que permite simular el comportamiento en rotura del panel sándwich conjunto. Por último se presentan los resultados de los ensayos de fractura en modo mixto (tracción/cortante de paneles comerciales y se reproduce su comportamiento con el modelo cohesivo propuesto, obteniéndose un buen ajuste.

  17. The optimization design and parametric study of thermoelectric radiant cooling and heating panel

    International Nuclear Information System (INIS)

    Shen, Limei; Tu, Zhilong; Hu, Qiang; Tao, Cheng; Chen, Huanxin

    2017-01-01

    Highlights: • Design procedure of TE radiant panel is proposed. • Thermal physical model combined thermoelectric effect and radiation law is developed. • An optimization design configuration of TE radiant panel is presented and validated. • The temperature distribution uniformity of TE radiant panel is studied. • We discuss the thermal characterization representation approach of TE radiant. - Abstract: Thermoelectric radiant air-conditioning (TE-RAC) system is a promising approach to implement thermoelectric technology in large-scale refrigeration system applications in future. However, no standard exists for the in situ design and the performance evaluation of thermoelectric radiant heating/cooling panel. Thus, this study aims to not only clarify the design procedure but also to share our thermal physical model and design configurations of the thermoelectric radiant panel to serve as a reference for other similar design cases. In addition, a simplified representation approach for the thermal characterization of thermoelectric panels is also discussed. The main design variables are the number of thermoelectric modules and the size of radiant panels. The inner surface transient temperature distribution of thermoelectric radiant panels is discussed, and the approaches for improving the uniformity of the inner surface temperature are proposed. The influence of cooling/heating load on the uniformity of the inner surface temperature is a slight larger than the size of the panel, so the matching design is very important. The results show that the optimal thickness of thermoelectric radiant panels is 4 mm, and the number of thermoelectric modules (TEM) is 16 per square meter, which also could solve the issues about dew formation and uniformity of inner surface temperature.

  18. Reading touch screen storybooks with mothers negatively affects seven-year-old readers’ comprehension but enriches emotional engagement

    Directory of Open Access Journals (Sweden)

    Kirsty Mhairi Ross

    2016-11-01

    Full Text Available Touch screen storybooks turn reading into an interactive multimedia experience, with hotspot-activated animations, sound effects, and games. Positive and negative effects of reading multimedia stories have been reported, but the underlying mechanisms which explain how children’s learning is affected remain uncertain. The present study examined the effect of storybook format (touch screen and print on story comprehension, and considered how level of touch screen interactivity (high and low and shared reading behaviors (cognitive and emotional scaffolding, emotional engagement might contribute to comprehension. Seven-year-olds (n = 22 were observed reading one touch screen storybook and one print storybook with their mothers. Story comprehension was inferior for the touch screen storybooks compared to the print versions. Touch screen interactivity had no significant effect on comprehension but did affect shared reading behaviors. The mother-child dyads spent less time talking about the story in the highly interactive touch screen condition, despite longer shared reading sessions because of touch screen interactions. Positive emotional engagement was greater for children and mothers in the highly interactive touch screen condition, due to additional positive emotions expressed during touch screen interactions. Negative emotional engagement was greater for children when reading and talking about the story in the highly interactive condition, and some mothers demonstrated negative emotional engagement with the touch screen activities. The less interactive touch screen storybook had little effect on shared reading behaviors, but mothers controlling behaviors were more frequent. Storybook format had no effect on the frequency of mothers’ cognitive scaffolding behaviors (comprehension questions, word help. Relationships between comprehension and shared reading behaviors were examined for each storybook, and length of the shared reading session and

  19. 2010 ICA Panel on Methodologies for Studying Virtual Worlds

    DEFF Research Database (Denmark)

    Hansbøl, Mikala; Reinhard, CarrieLynn D.; Ho, Caroline

    2010-01-01

    strategies qualitatively from 00:12:00-00:19:30 •CarrieLynn D. Reinhard speaks about merging quantitative and qualitative methods from 00:19:30-00:29:30 •Mikala Hansbøl speaks about qualitative analysis of a serious educational game from 00:29:30-00:40:00 •The question and answer period is from 00:51:15-01:08:00......This video was produced from a panel discussion at the 2010 International Communication Association conference in Singapore. The panelists are Dmitri Williams (University of Southern California), Mikala Hansbøl (Danish School of Education), Caroline Ho (National Institute of Education, Singapore...

  20. Intervention on early-onset conduct problems as indicated prevention for substance use: A seven-year follow up.

    Science.gov (United States)

    Romero, Estrella; Rodríguez, Concepción; Villar, Paula; Gómez-Fraguela, X Antón

    2017-06-28

    The aim of this study is to evaluate the long-term effects of a manualised program which intervenes on children with early-onset conduct problems, their families and teachers. The program evaluation involved 14 primary schools which were randomly assigned to the intervention (45 participating families) and control (30 families) conditions during 2007-2008. After a screening process which identified children with significant conduct problems both at home with their family and at school, the program was implemented in eight schools. Seven years later, 58 families (37 from the intervention group and 21 from the control group), with characteristics equivalent to those of the study's entire initial group, were contacted again. With measures administered to the children and their parents, comparisons through multivariate analyses of variance between intervention and control groups supported the program's efficacy in reducing both conduct problems and relations with antisocial peers. Furthermore, the program fostered social and communication skills. As regards drug use, the intervention group showed less favourable attitudes towards drugs, lower intention of drug use, lower frequency of tobacco use and lower intensity of alcohol use. These results support the usefulness of multicomponent programs for conduct problems as a way to prevent, in the long term, unfavourable developmental trajectories, where drug use is a key element.

  1. IceCube results from point-like source searches using seven years of through-going muon data

    Energy Technology Data Exchange (ETDEWEB)

    Coenders, Stefan; Resconi, Elisa [Technische Universitaet Muenchen, Boltzmannstr. 2, 85748 Garching (Germany); Collaboration: IceCube-Collaboration

    2016-07-01

    The IceCube Neutrino Observatory located at the geographic South Pole was designed to study and discover high-energy neutrinos coming from both galactic and extragalactic sources. Track-like events induced by charged-current muon-neutrino interactions close to the IceCube detector give an angular resolution better than 1 degree above TeV energies. Within seven years of detector lifetime, IceCube selects more than 700,000 events over the full sky, plus an additional component of almost 1000 events that are identified to be starting in the detector in the southern sky. Using this event sample, IceCube is sensitive to a steady neutrino flux substantially below E{sup 2} ∂ φ/∂ E = 10{sup -12} TeV cm{sup -2} s{sup -1} in the northern sky for neutrino energies above 10 TeV. We report about the results in this search for steady point-like neutrino sources.

  2. Erosion of mountain hiking trail over a seven-year period in Daisetsuzan National Park, central Hokkaido, Japan

    Science.gov (United States)

    Akemi Yoda; Teiji Watanabe

    2000-01-01

    Erosion of mountain hiking trails was investigated in Daisetsuzan National Park over a seven-year period. The amount and rate of erosion were different in the two typical landscape components. Cross-section diagrams revealed that trail depth became deeper in snowy vegetated areas than in wind-beaten bare ground areas. The existence and timing of runoff from snowmelt...

  3. From the Editors: Seven years on the editorial team of the Journal of Airline and Airport Management (JAIRM

    Directory of Open Access Journals (Sweden)

    Pep Simo

    2018-01-01

    Full Text Available The goal of this editorial is to provide a short review of the seven years in which I have formed part of the editorial team of the JAIRM as editor-in-chief, and to suggest the challenges that, from my point of view, are key to the development of the magazine and this area of research.

  4. Psychotic symptoms in older people without dementia from a Brazilian community-based sample: A seven years' follow-up.

    Directory of Open Access Journals (Sweden)

    Walter Barbalho Soares

    Full Text Available Studies of the incidence of psychotic symptoms in elderly people at risk of dementia are scarce. This is a seven year follow up study aiming to determine the incidence of psychotic symptoms and their correlation with other clinical aspects, in particular the rate of development of cognitive impairment.Cohort study of a community-based sample of elderly subjects. At study entry in 2004, the sample was composed of 1,125 individuals aged 60 years and older. Of this total, 547 subjects were re-evaluated in 2011 and submitted to the original study protocol. Of these, 199 showed no psychotic symptoms at phase I, while 64 already had psychotic symptoms in 2004.The incidence of at least one psychotic symptom in the 7 year period was 8.0% (Visual/tactile hallucinations: 4.5%; Persecutory delusions: 3.0%; Auditory hallucinations: 2.5%. Development of psychotic symptoms was associated with epilepsy (OR: 7.75 and 15.83, lower MMSE (OR: 0.72 and reported depression (OR: 6.48. A total of 57.8% of individuals with psychotic symptoms developed cognitive impairment after 7 years. Visual/tactile hallucinations were the only psychotic symptom predictive of this impairment, which was related to lower MMSE and greater functional impairment.The incidence of psychotic symptoms and the conversion rate to cognitive impairment was in the upper range when compared with previous reports. Visual/tactile hallucinations were the most frequent symptoms and were predictive of cognitive impairment over the 7 year period. A significant relationship was found between the incidence of psychotic symptoms and low MMSE scores, as well as clinical comorbities such as epilepsy, reported depression, diabetes and syphilis.

  5. Psychotic symptoms in older people without dementia from a Brazilian community-based sample: A seven years' follow-up.

    Science.gov (United States)

    Soares, Walter Barbalho; Dos Santos, Eriton Barros; Bottino, Cássio Machado de Campos; Elkis, Helio

    2017-01-01

    Studies of the incidence of psychotic symptoms in elderly people at risk of dementia are scarce. This is a seven year follow up study aiming to determine the incidence of psychotic symptoms and their correlation with other clinical aspects, in particular the rate of development of cognitive impairment. Cohort study of a community-based sample of elderly subjects. At study entry in 2004, the sample was composed of 1,125 individuals aged 60 years and older. Of this total, 547 subjects were re-evaluated in 2011 and submitted to the original study protocol. Of these, 199 showed no psychotic symptoms at phase I, while 64 already had psychotic symptoms in 2004. The incidence of at least one psychotic symptom in the 7 year period was 8.0% (Visual/tactile hallucinations: 4.5%; Persecutory delusions: 3.0%; Auditory hallucinations: 2.5%). Development of psychotic symptoms was associated with epilepsy (OR: 7.75 and 15.83), lower MMSE (OR: 0.72) and reported depression (OR: 6.48). A total of 57.8% of individuals with psychotic symptoms developed cognitive impairment after 7 years. Visual/tactile hallucinations were the only psychotic symptom predictive of this impairment, which was related to lower MMSE and greater functional impairment. The incidence of psychotic symptoms and the conversion rate to cognitive impairment was in the upper range when compared with previous reports. Visual/tactile hallucinations were the most frequent symptoms and were predictive of cognitive impairment over the 7 year period. A significant relationship was found between the incidence of psychotic symptoms and low MMSE scores, as well as clinical comorbities such as epilepsy, reported depression, diabetes and syphilis.

  6. Qualitative study of college tutoring through the expert panel method

    Directory of Open Access Journals (Sweden)

    Inmaculada López Martín

    2014-03-01

    Full Text Available The implementation of a quality Tutorial Action Plan (TAP, in which the integral formation of students is the main objective, is a topical issue in the Spanish university environment . This paper aims to identify the actions contemplated in the TAPs of different Spanish universities and catalog the different types of activities performed by the teachers-tutors in the context of tutorial action. To achieve this, the authors conducted a qualitative analysis based on expert panels. As a result, three main vectors were extracted: Standard elements in a college TAP, critical aspects from tutors and managers of tutorial actions, and tutorial actions with a seal of quality. From the analysis it was concluded that quality tutorial action is the basis for academic excellence. Its achievement requires to clarify and recognize the role of the tutor, adjust appropriately the ratio of students allocated per tutor, and promote the development of transversal skills in students. For this, the authors propose a cross-coordination among teachers, as well as counseling and support; tutor training and professionalism; and the application of working methods that allow proper guidance and monitoring of students. ----------------------------- Estudio Cualitativo sobre Tutoría Universitaria a Través del Método de Panel de Expertos Resumen La implantación de un plan de acción tutorial (PAT de calidad, en el cual la formación integral del alumnado sea lo principal, es un tema de actualidad en el entorno universitario español. El presente trabajo persigue identificar las acciones contempladas en los PAT de diferentes universidades españolas, así como catalogar los diferentes tipos de actividades realizadas por los profesores-tutores en el contexto de la acción tutorial. Para ello se realizó un análisis cualitativo basado en paneles de expertos. Como resultado, se extrajeron tres vectores principales: Elementos habituales en un PAT universitario; Aspectos cr

  7. Seven years of growth hormone (GH) replacement improves quality of life in hypopituitary patients with adult-onset GH deficiency.

    Science.gov (United States)

    Elbornsson, Mariam; Horvath, Alexandra; Götherström, Galina; Bengtsson, Bengt-Åke; Johannsson, Gudmundur; Svensson, Johan

    2017-02-01

    Few studies have determined the effects of long-term growth hormone (GH) replacement on quality of life (QoL). This study investigated the effects of 7 years of GH replacement on QoL. A prospective, single-center, open-label study of 95 adults (mean age 52.8 years; 46 men) with adult-onset GH deficiency (GHD). QoL was measured using Quality of Life-Assessment for Growth Hormone Deficiency in Adults (QoL-AGHDA) and Psychological General Well-Being (PGWB) scores. The GH dose was gradually increased from 0.13 mg/day to 0.42 mg/day. IGF-I SD score increased from -1.49 at baseline to 0.35 at study end. The GH replacement induced sustained improvements in total QoL-AGHDA and PGWB scores. GHD women had a more marked improvement in total QoL-AGHDA score than GHD men after 5 and 7 years. Most of the improvement in QoL was seen during the first year, but there was a small further improvement also after one year as measured using QoL-AGHDA. All QoL-AGHDA dimensions improved, but the improvement in memory and concentration as well as tenseness occurred later than that of other dimensions. Correlation analysis demonstrated that the patients with the lowest baseline QoL had the greatest improvement in QoL. Seven years of GH replacement improved QoL with the most marked improvements in GHD women and in patients with low baseline QoL. Most, but not all, of the improvement in QoL was seen during the first year. Some QoL-AGHDA dimensions (memory and concentration, tenseness) responded at a slower rate than other dimensions. © 2017 European Society of Endocrinology.

  8. Simulation Study of Discharging PCM Ceiling Panels through Night - time Radiative Cooling

    DEFF Research Database (Denmark)

    Bourdakis, Eleftherios; Kazanci, Ongun Berk; Grossule, F.

    2016-01-01

    demand. In the present simulation study, the coupling of nighttime radiative cooling with PCM for cooling an office room was investigated. For cooling water through nighttime radiative cooling two types of solar panels were utilized, an unglazed solar collector and photovoltaic/thermal (PV/T) panels...... provided by the PV/T panels was 43 W/m2 for Copenhagen, while for Milan and Athens it was 36 W/m2 and 34 W/m2, respectively. The cooling power of the unglazed solar collector was negligible. Finally, the total electricity produced in Copenhagen for the simulated period was 371 kWh, while for Milan...... and increase use of renewable energy sources. The aim is that by 2020 all new buildings should be nearly zero-energy buildings. A solution that could contribute to this is the combination of photovoltaic panels for the production of electricity and phase change material (PCM) for the reduction of peak cooling...

  9. Ozone exposure and pulmonary effects in panel and human clinical studies: Considerations for design and interpretation.

    Science.gov (United States)

    Rohr, Annette C

    2018-04-01

    A wealth of literature exists regarding the pulmonary effects of ozone, a photochemical pollutant produced by the reaction of nitrogen oxide and volatile organic precursors in the presence of sunlight. This paper focuses on epidemiological panel studies and human clinical studies of ozone exposure, and discusses issues specific to this pollutant that may influence study design and interpretation as well as other, broader considerations relevant to ozone-health research. The issues are discussed using examples drawn from the wider literature. The recent panel and clinical literature is also reviewed. Health outcomes considered include lung function, symptoms, and pulmonary inflammation. Issues discussed include adversity, reversibility, adaptation, variability in ozone exposure metric used and health outcomes evaluated, co-pollutants in panel studies, influence of temperature in panel studies, and multiple comparisons. Improvements in and standardization of panel study approaches are recommended to facilitate comparisons between studies as well as meta-analyses. Additional clinical studies at or near the current National Ambient Air Quality Standard (NAAQS) of 70 ppb are recommended, as are clinical studies in sensitive subpopulations such as asthmatics. The pulmonary health impacts of ozone exposure have been well documented using both epidemiological and chamber study designs. However, there are a number of specific methodological and related issues that should be considered when interpreting the results of these studies and planning additional research, including the standardization of exposure and health metrics to facilitate comparisons among studies.

  10. Using archetypes to create user panels for usability studies: Streamlining focus groups and user studies.

    Science.gov (United States)

    Stavrakos, S-K; Ahmed-Kristensen, S; Goldman, T

    2016-09-01

    Designers at the conceptual phase of products such as headphones, stress the importance of comfort, e.g. executing comfort studies and the need for a reliable user panel. This paper proposes a methodology to issue a reliable user panel to represent large populations and validates the proposed framework to predict comfort factors, such as physical fit. Data of 200 heads was analyzed by forming clusters, 9 archetypal people were identified out of a 200 people's ear database. The archetypes were validated by comparing the archetypes' responses on physical fit against those of 20 participants interacting with 6 headsets. This paper suggests a new method of selecting representative user samples for prototype testing compared to costly and time consuming methods which relied on the analysis of human geometry of large populations. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Spectroscopic study of an icon painted on wooden panel

    Directory of Open Access Journals (Sweden)

    Stojanović Sofija R.

    2015-01-01

    Full Text Available Russian icon painted on wooden panel analyzed in this work is interesting for art historians because there is no precise information in which workshops it was made or who the author was. Similar icons are often found in churches and monasteries in our region. In order to obtain information about materials used for creation of investigated icon two micro-analytical techniques were used: Energy-Dispersive X-Ray Fluorescence spectroscopy (EDXRF and micro-Raman spectroscopy. Obtained results confirmed presence of following materials: lead-white, vermilion, minium, ultramarine, brown and green earth pigments and silver in combination with yellow organic varnish, which served to an iconographer for gilding. Ground layer was made of calcite. Blue pigment ultramarine was probably used for blue colour as well as for obtaining particulars hues in several parts of the paint layer. This can be important information for further research concerning particular workshop in which the icon was made. Identified materials are typical for Russian iconography of the 19th century. [Projekat Ministarstva nauke Republike Srbije, br. OI 177021 i OI 177012

  12. Characterization of Forty Seven Years of Particulate Chemical Composition in the Finnish Arctic

    Science.gov (United States)

    Laing, James

    Forty seven years of weekly total suspended particle filters collected at Kevo, Finland from October 1964 through 2010 by the Finnish Meteorological Institute were analyzed for near-total trace elements, soluble trace elements, black carbon (BC), and major ions and methane sulfonic acid (MSA). Kevo is located in Northern Finland, 350 km north of the Arctic Circle. The samples from 1964-1978 were collected with Whatman 42 cellulous filters and the samples from 1979-2010 collected on Whatman GF/A glass-fiber filters. A portion of the filters was microwave acid-digested (ad) and analyzed for near-total trace elements were determined by inductively coupled plasma mass spectrometry (ICP-MS). Another portion was water extracted (we) and analyzed for soluble trace elements by ICP-MS and ionic species by ion chromatography (IC). Black carbon (BC) was determined using optical and thermal optical techniques at SUNY Albany. A clear seasonal trend with winter/spring maxima and summer minima is observed for most species attributed to enhanced transport of pollutants from anthropogenic mid-latitude sources to the Arctic in the winter and early spring. Compared to more remote Arctic sampling sites, species of anthropogenic origin (V, Co, Cu, Ni, As, Cd, Pb, SO4) have significantly higher concentrations and a less pronounced seasonality. High concentrations of Cu (14.1 ng/m3), Ni (0.97 ng/m3), and Co (0.04 ng/m3) indicate the influence of non-ferrous metal smelters on the Kola Peninsula, although Cu unexpectedly did not correlate with Ni or Co. Ni and Co were highly correlated. Significant long-term decreasing trends were detected for most species. All constituents except Sn-ad, Re-ad, Sn-we, Mo-we, V-we, have significant (p sea salt SO4 concentrations were found to have a very similar trend to European and Former Soviet Union SO2 emissions. SO4 concentrations declined dramatically in the early 1990s a result of the collapse of the Soviet Union. Potential source contribution

  13. A seven-year disease-free survivor of malignant pleural mesothelioma treated with hyperthermia and chemotherapy: a case report

    Directory of Open Access Journals (Sweden)

    Okonogi Noriyuki

    2012-12-01

    Full Text Available Abstract Introduction Malignant pleural mesothelioma was once a rare finding but its incidence is increasing worldwide, most likely because of widespread exposure to asbestos. Although complete surgical resection is considered the only curative treatment, the results of surgery have shown a median survival time of only one year. In inoperable cases, chemotherapy, radiotherapy, and a combination of both have been considered as palliative therapy. Therefore, outcomes for inoperable cases have been poor. Here, we report the case of a long-term survivor treated with hyperthermia and chemotherapy. Case presentation A 61-year-old Japanese man with a performance status of 1 due to chest pain was referred to our hospital. He had a history of asbestos exposure for approximately five years. A computed tomography scan showed diffuse extensive right pleural thickening with small nodular lesions, and video-assisted thoracoscopy revealed tumor invasion of the ipsilateral chest wall muscles. The histopathologic findings were consistent with a diagnosis of malignant pleural mesothelioma (sarcomatoid type. The tumor was diagnosed as being stage cT3N0M0. Our patient refused any invasive therapies including surgery and radiotherapy, and was therefore treated with hyperthermia and systemic chemotherapy with agents such as cisplatin and irinotecan. He underwent three hyperthermia sessions and a single course of chemotherapy without any severe complications. One month after treatment, a follow-up computed tomography scan showed no definitive abnormality in the thoracic space. Our patient has subsequently survived without any evident disease for more than seven years. Conclusions The combination of hyperthermia and chemotherapy may be a novel and safe therapeutic option for malignant pleural mesothelioma, and can be considered for patients ineligible for radical treatment. Further clinical studies of the combination of hyperthermia and chemotherapy are needed to

  14. Performance study on the east-west oriented single-axis tracked panel

    International Nuclear Information System (INIS)

    Chang, Tian Pau

    2009-01-01

    A theoretical study on the performance of an east-west oriented single-axis tracked panel was originally proposed in this paper. Mathematic expressions applicable for calculating the angle that the tracked panel should rotate by to follow the Sun are derived. The incident angle of sunlight upon the panel as well as the instantaneous increments of solar energy captured by the panel relative to a fixed horizontal surface are then demonstrated graphically. To simulate different operation environments, three kinds of radiation sources will be considered, i.e. the extraterrestrial radiation, global radiation predicted by empirical models under clear sky situation and global radiation observed in Taiwan. Simulation results show that the yearly gains correlate positively with the radiation level, i.e. 21.2%, 13.5% and 7.4% for the extraterrestrial, predicted and observed radiations, respectively, which are far less than those obtained from a north-south oriented single-axis tracked panel. The irradiation increases with the maximum rotation angle of the panel, the benefit of increasing the rotation in overcast environment is not as good as in clear sky, for annual energy collection 45 o is recommended. The irradiation received decreases with latitude, but it has a greater gain in higher latitude zone.

  15. Dynamic heat transfer modeling and parametric study of thermoelectric radiant cooling and heating panel system

    International Nuclear Information System (INIS)

    Luo, Yongqiang; Zhang, Ling; Liu, Zhongbing; Wang, Yingzi; Wu, Jing; Wang, Xiliang

    2016-01-01

    Highlights: • Dynamic model of thermoelectric radiant panel system is established. • The internal parameters of thermoelectric module are dynamically calculated in simulation. • Both artificial neural networks model and system model are verified through experiment data. • Optimized system structure is obtained through parametric study. - Abstract: Radiant panel system can optimize indoor thermal comfort with lower energy consumption. The thermoelectric radiant panel (TERP) system is a new and effective prototype of radiant system using thermoelectric module (TEM) instead of conventional water pipes, as heat source. The TERP can realize more stable and easier system control as well as lower initial and operative cost. In this study, an improved system dynamic model was established by combining analytical system model and artificial neural networks (ANN) as well as the dynamic calculation functions of internal parameters of TEM. The double integral was used for the calculation of surface average temperature of TERP. The ANN model and system model were in good agreement with experiment data in both cooling and heating mode. In order to optimize the system design structure, parametric study was conducted in terms of the thickness of aluminum panel and insulation, as well as the arrangement of TEMs on the surface of radiant panel. It was found through simulation results that the optimum thickness of aluminum panel and insulation are respectively around 1–2 mm and 40–50 mm. In addition, TEMs should be uniformly installed on the surface of radiant panel and each TEM should stand at the central position of a square-shaped typical region with length around 0.387–0.548 m.

  16. Demographic and psychological predictors of panel attrition: evidence from the New Zealand attitudes and values study.

    Directory of Open Access Journals (Sweden)

    Nicole Satherley

    Full Text Available This study examines attrition rates over the first four years of the New Zealand Attitudes and Values Study, a longitudinal national panel sample of New Zealand adults. We report the base rate and covariates for the following four distinct classes of respondents: explicit withdrawals, lost respondents, intermittent respondents and constant respondents. A multinomial logistic regression examined an extensive range of demographic and socio-psychological covariates (among them the Big-Six personality traits associated with membership in these classes (N = 5,814. Results indicated that men, Māori and Asian peoples were less likely to be constant respondents. Conscientiousness and Honesty-Humility were also positively associated with membership in the constant respondent class. Notably, the effect sizes for the socio-psychological covariates of panel attrition tended to match or exceed those of standard demographic covariates. This investigation broadens the focus of research on panel attrition beyond demographics by including a comprehensive set of socio-psychological covariates. Our findings show that core psychological covariates convey important information about panel attrition, and are practically important to the management of longitudinal panel samples like the New Zealand Attitudes and Values Study.

  17. An experimental hut evaluation of Olyset® nets against anopheline mosquitoes after seven years use in Tanzanian villages

    Directory of Open Access Journals (Sweden)

    Mosha Frank W

    2008-02-01

    Full Text Available Abstract Background Long-lasting insecticidal nets (LLINs are advocated by WHO for protection against malaria. Of the three brands of LLINs currently approved by WHO, Olyset® is the only one currently granted full recommendation. With this type of LLIN, the insecticide (permethrin is incorporated into the polyethylene fibre during manufacture and diffuses from the core to the surface, thereby maintaining surface concentrations. It has not been determined for how long Olyset nets remain protective against mosquitoes in household use. Methods Examples of Olyset nets, which had been in use in Tanzanian villages for seven years, were tested in experimental huts against naturally entering Anopheles gambiae and Anopheles funestus mosquitoes. Performance was compared with new Olyset nets, conventionally treated ITNs (either newly treated with alphacypermethrin or taken from local villages after 1.5 years of use and untreated nets. All nets were artificially holed except for the seven-year Olyset nets, which had developed holes during prolonged domestic use. Results Anopheles funestus and An. gambiae in NE Tanzania are susceptible to pyrethroids. The new Olyset nets caused high mortality against An. funestus (73.9% and An. gambiae (62.7% in experimental huts. The seven-year Olyset nets caused 58.9% mortality against An. funestus and 40.0% mortality against An. gambiae. The freshly treated alphacypermethrin nets also caused high mortality against An. funestus (70.6% and An. gambiae (72.0%; this decreased to 58.4% and 69.6% respectively after 1.5 years of use. The new Olyset nets inhibited blood-feeding by 40–50%. The 7 year Olyset nets showed no feeding inhibition over that shown by the untreated nets. The alphacypermethrin treated nets failed to inhibit blood-feeding after 1.5 years of use. However iHhhdn laboratory tunnel tests samples of all types of treated net including the 7 year Olyset inhibited blood-feeding by more than 95%. Conclusion After

  18. The impact of gender and parenthood on physicians' careers - professional and personal situation seven years after graduation

    Directory of Open Access Journals (Sweden)

    Knecht Michaela

    2010-02-01

    Full Text Available Abstract Background The profile of the medical profession is changing in regard to feminization, attitudes towards the profession, and the lifestyle aspirations of young physicians. The issues addressed in this study are the careers of female and male physicians seven years after graduation and the impact of parenthood on career development. Methods Data reported originates from the fifth assessment (T5 of the prospective SwissMedCareer Study, beginning in 2001 (T1. At T5 in 2009, 579 residents (81.4% of the initial sample at T1 participated in the questionnaire survey. They were asked about occupational factors, career-related factors including specialty choice and workplace, work-life balance and life satisfaction. The impact of gender and parenthood on the continuous variables was investigated by means of multivariate and univariate analyses of variance; categorical variables were analyzed using Chi-square tests. Results Female physicians, especially those with children, have lower rates of employment and show lower values in terms of career success and career support experiences than male physicians. In addition, parenthood has a negative impact on these career factors. In terms of work-life balance aspired to, female doctors are less career-oriented and are more inclined to consider part-time work or to continue their professional career following a break to bring up a family. Parenthood means less career-orientation and more part-time orientation. As regards life satisfaction, females show higher levels of satisfaction overall, especially where friends, leisure activities, and income are concerned. Compared to their male colleagues, female physicians are less advanced in their specialty qualification, are less prone to choosing prestigious surgical fields, have a mentor less often, more often work at small hospitals or in private practice, aspire less often to senior hospital or academic positions and consider part-time work more often

  19. The impact of gender and parenthood on physicians' careers--professional and personal situation seven years after graduation.

    Science.gov (United States)

    Buddeberg-Fischer, Barbara; Stamm, Martina; Buddeberg, Claus; Bauer, Georg; Häemmig, Oliver; Knecht, Michaela; Klaghofer, Richard

    2010-02-18

    The profile of the medical profession is changing in regard to feminization, attitudes towards the profession, and the lifestyle aspirations of young physicians. The issues addressed in this study are the careers of female and male physicians seven years after graduation and the impact of parenthood on career development. Data reported originates from the fifth assessment (T5) of the prospective SwissMedCareer Study, beginning in 2001 (T1). At T5 in 2009, 579 residents (81.4% of the initial sample at T1) participated in the questionnaire survey. They were asked about occupational factors, career-related factors including specialty choice and workplace, work-life balance and life satisfaction. The impact of gender and parenthood on the continuous variables was investigated by means of multivariate and univariate analyses of variance; categorical variables were analyzed using Chi-square tests. Female physicians, especially those with children, have lower rates of employment and show lower values in terms of career success and career support experiences than male physicians. In addition, parenthood has a negative impact on these career factors. In terms of work-life balance aspired to, female doctors are less career-oriented and are more inclined to consider part-time work or to continue their professional career following a break to bring up a family. Parenthood means less career-orientation and more part-time orientation. As regards life satisfaction, females show higher levels of satisfaction overall, especially where friends, leisure activities, and income are concerned. Compared to their male colleagues, female physicians are less advanced in their specialty qualification, are less prone to choosing prestigious surgical fields, have a mentor less often, more often work at small hospitals or in private practice, aspire less often to senior hospital or academic positions and consider part-time work more often. Any negative impact on career path and advancement is

  20. Treatment for neovascular age-related macular degeneration in Sweden: outcomes at seven years in the Swedish Macula Register.

    Science.gov (United States)

    Westborg, Inger; Granstam, Elisabet; Rosso, Aldana; Albrecht, Susanne; Karlsson, Niklas; Lövestam-Adrian, Monica

    2017-12-01

    To present Swedish Macula Register (SMR) data regarding treatment of neovascular age-related macular degeneration (AMD) in clinical practice since 2008. A retrospective register-based study was conducted. Evaluation of baseline demographics, visual outcome and number of injections during this period is presented. Mean age at diagnosis was 79 ± (SD) 8 years; 65% were female. The proportion of patients with <2 months' duration of symptoms increased from 26% in 2008 to 41% in 2014 (p = 0.001). Mean visual acuity (VA) at baseline increased from 54.3 ± 15.0 early treatment diabetic retinopathy study (ETDRS) letters in 2008 to 57.8 ± 15.6 letters in 2014 (CI 95 2.6; 4.3; p < 0.001). Mean VA after 1 year of treatment increased from 57.8 ± 17.7 ETDRS letters for patients who started the treatment in 2008 to 62.8 ± 16.4 ETDRS letters in patients starting treatment in 2014 (CI 95 2.67; 4.64; p < 0.001). During all study years, the proportion of patients with an improvement in VA of between 5 and 15 letters was around 30%, while 14% had VA improvement of more than 15 letters. The mean number of injections during the first treatment year increased from 4.3 ± 1.9 in 2008 to 5.9 ± 2.9 in 2014 (CI 95 1.40; 1.67; p < 0.001). Seven-year follow-up of 322 eyes showed a mean change of -1 letters from baseline, with a mean of 21 injections for the entire period. The duration of symptoms before treatment decreased, while VA at baseline and after 1 year of treatment increased over the years and so did the number of injections. Long-term follow-up demonstrated stable VA. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  1. Comparative study on the mechanical performance of beech and ash laminated panels

    Directory of Open Access Journals (Sweden)

    Andreea HEGYI

    2014-07-01

    Full Text Available This paper presents a comparative study on the mechanical performance of beech and ash wood laminated panels. Within the experimental study the bending strength, bending modulus of elasticity and the bonding characteristics to gluing (bonding quality were analyzed. The experimental results emphasized the influence of the type of wood, the panel thickness, the effect on the bending strength, respectively on the gluing quality of the direction of the wood lamellas in relation with the mechanical load (direction of cutting specimens. It can be said that the use of hardwood meets the needs and demands of the construction area, but it’s necessary a careful analysis of the requests that occur mainly at the site, thus an optimal direction of the wooden glued lamellas can be chosen. Laminated wood panels are a product with real physical and mechanical qualities, which can be successfully used to obtain construction elements that are bringing benefits to environmental quality of living areas.

  2. Authoritative parenting and religious transmission in the Netherlands: a panel study

    NARCIS (Netherlands)

    Vermeer, P.A.D.M.; Janssen, J.A.P.J.; Scheepers, P.L.H.

    2011-01-01

    This study was designed to explore the effect of authoritative parenting, over and above the effect of explicitly religious parenting practices, on the juvenile and adult church attendance of offspring. Data were collected as part of a panel study in which 474 Dutch respondents were questioned in

  3. Air pollution and respiratory health of children: the PEACE panel study in Umea., Sweden.

    NARCIS (Netherlands)

    Forsberg, B.; Segerstedt, B.; Stjernberg, N.; Roemer, W.

    1998-01-01

    The Pollution Effects on Asthmatic Children in Europe (PEACE) study examined the acute effects of short-term changes in air pollution on symptomatic children. We were one of 14 research centres in Europe that used a common study protocol. Seventy five children in an urban panel and 72 children in a

  4. Air pollution and respiratory health of children: the PEACE panel study in Katowice, Poland.

    NARCIS (Netherlands)

    Niepsuj, G.; Niepsuj, K.; Nieroda-Muller, A.; Rauer, R.; Krzywiecki, Z.; Borowska, M.; Hlawiczka, Z.; Brunekreef, B.

    1998-01-01

    This study was carried out within the framework of the multicentre Pollution Effects on Asthmatic Children in Europe (PEACE) project. Two panels of mildly asthmatic children were studied. Seventy two children living in the Upper Silesia (the largest Polish industrial agglomeration) and 73 children

  5. Air pollution and respiratory health of children: the PEACE panel study in Krakow., Poland.

    NARCIS (Netherlands)

    Haluszka, J.; Pisiewics, K.; Miczynski, J.; Roemer, W.; Tomalak, W.

    1998-01-01

    The Krakow panel study was performed as part of the Pollution Effects on Asthmatic Children in Europe (PEACE) project. The aim of the study was to examine the acute effects of short-term changes in air pollution on symptomatic children. Krakow served as the urban area and Rabka, a small health

  6. Sound absorption study on acoustic panel from kapok fiber and egg tray

    Science.gov (United States)

    Kaamin, Masiri; Mahir, Nurul Syazwani Mohd; Kadir, Aslila Abd; Hamid, Nor Baizura; Mokhtar, Mardiha; Ngadiman, Norhayati

    2017-12-01

    Noise also known as a sound, especially one that is loud or unpleasant or that causes disruption. The level of noise can be reduced by using sound absorption panel. Currently, the market produces sound absorption panel, which use synthetic fibers that can cause harmful effects to the health of consumers. An awareness of using natural fibers from natural materials gets attention of some parties to use it as a sound absorbing material. Therefore, this study was conducted to investigate the potential of sound absorption panel using egg trays and kapok fibers. The test involved in this study was impedance tube test which aims to get sound absorption coefficient (SAC). The results showed that there was good sound absorption at low frequency from 0 Hz up to 900 Hz where the maximum absorption coefficient was 0.950 while the maximum absorption at high frequencies was 0.799. Through the noise reduction coefficient (NRC), the material produced NRC of 0.57 indicates that the materials are very absorbing. In addition, the reverberation room test was carried out to get the value of reverberation time (RT) in unit seconds. Overall this panel showed good results at low frequencies between 0 Hz up to 1500 Hz. In that range of frequency, the maximum reverberation time for the panel was 3.784 seconds compared to the maximum reverberation time for an empty room was 5.798 seconds. This study indicated that kapok fiber and egg tray as the material of absorption panel has a potential as environmental and cheap products in absorbing sound at low frequency.

  7. [Correlations between features of social network and outcomes in those suffering from schizophrenia seven years from the first hospitalisation].

    Science.gov (United States)

    Cechnicki, Andrzej; Wojciechowska, Anna

    2007-01-01

    A research had been conducted upon the correlations between selected parameters of social networks of 64 patients ill with schizophrenia who were diagnosed according to DSM-III, and the aims of treatment such as: motivation to receive treatment, insight, compliance in taking medication, satisfaction with treatment, and treatment outcomes in the area of clinical and social functioning as well as family functioning seven years after the first admission. The indices of social networks were studied with Bizon's questionnaire. It serves storing of data on persons who have supportive functions as well as allows to work out characteristic properties of the support system such as: range of the network, size of the extra-familial network, level and localisation of the support, network and support system age. A compound system of social support and large social network, with a high level of support, correlate in a beneficial way with higher subjective satisfaction with treatment. Whereas a large extra-familial network with high level of support, correlates with better insight into illness. The larger the social network was (its range to be precise), including extra-familial network and the high level of incoming support, the fewer positive and negative symptoms the patients had and much more remissions appeared then. The larger network's range correlates with smaller number of relapses and global time of being hospitalised. People with a larger network, with high level of support located in family and outside the family, have been rarely hospitalised. The connection between network's parameters and number of daily hospitalisations had been rated. People with a larger network, including extra-familial network, with high level of social support function better in the society didn't become regressive in their professional lives and they have smaller burden in their family life. The high level of social support correlates with better family function. In families of people ill

  8. Effects of microelements on soil nematode assemblages seven years after contaminating an agricultural field

    NARCIS (Netherlands)

    Nagy, P.; Bakonyi, G.; Bongers, A.M.T.; Kádár, I.; Fábián, M.; Kiss, I.

    2004-01-01

    Long-term effects of Cd, Cr, Cu, Se and Zn were studied 7 years after artificially contaminating plots of an agricultural field on a calcareous chernozem soil. Effects of three to four different contamination levels (originally 10, 30, 90 and 270 mg kg(-1)) were studied. Nematode density was

  9. Can unexplained infertility be evaluated by a new immunological four-biomarkers panel? A pilot study.

    Science.gov (United States)

    Maxia, Nicoletta; Uccella, Stefano; Ersettigh, Gabriele; Fantuzzi, Mario; Manganini, Massimiliano; Scozzesi, Alessandro; Colognato, Renato

    2018-04-01

    Inflammation and oxidative stress are known to be triggering factors for a decrease of the pregnancy rate like maternal immunosuppression. Under these circumstances our study was performed to verify four immunological biomarkers (IMMUNOX Panel) in terms of incidence in a sine-causa infertile population and the overall pregnancy rate when the Panel was showing some non-physiologic values. Sera of 86 women affected by unexplained infertility were screened for the IMMUNOX panel of biomarkers composed by: tumor necrosis factor alpha (TNF-α,) glycodelin (GLY), total oxidative status (TOS), and complement activity toxic factor (CATF). When at least one of the biomarkers tested was showing values outside the physiologic range, the woman was considered IMMUNOX-Positive. The first data was indented to verify the incidence of the women with an IMMUNOX-positive panel. Results show that 19.8%, 18.6%, 25.6%, and 47.7% were IMMUNOX-positive for GLY, TNF-α, TOS and CATF respectively. The overall incidence of IMMUNOX-positive patients, with at least one biomarker positive was 70,9%. Subsequently we have analysed the correlation between IMMUNOX Panel positivity and the pregnancy rate. The pregnancy rate in a subgroup (N.=55) of the entire population tested (N.=86) was 2.9% and 36.6% for the IMMUNOX-positive and IMMUNOX-negative patients respectively. Further validation studies are needed to prove that there is a correlation between unexplained infertility and immunological disorders screened by the IMMUNOX Panel, nevertheless our data shows that this diagnostic approach may be helpful to predict and to identify women at higher risk of IVF cycles failure.

  10. Spasmodic dysphonia: a seven-year audit of dose titration and demographics in the Indian population.

    Science.gov (United States)

    Nerurkar, N K; Banu, T P

    2014-07-01

    This study aimed to evaluate the demographics of spasmodic dysphonia in the Indian population and to analyse the optimum dose titration of botulinum toxin type A in this group. A comparative analysis with international studies was also performed. The study involved a retrospective analysis and audit of botulinum toxin type A dose titration in spasmodic dysphonia patients who visited our voice clinic between January 2005 and January 2012. The average total therapeutic dose required for patients with adductor spasmodic dysphonia was 4.2 U per patient per vocal fold (total 8.4 U per patient), and for patients with abductor spasmodic dysphonia, it was 4.6 U per patient. Our audit revealed that 80 per cent of the spasmodic dysphonia patients were male, which contrasts dramatically with international studies, wherein around 80 per cent of spasmodic dysphonia patients were female. Our study also revealed a higher dose titration of botulinum toxin for the Indian spasmodic dysphonia population in both adductor and abductor spasmodic dysphonia cases.

  11. Limited Edge Effects Along a Burned-Unburned Bornean Forest Boundary Seven Years after Disturbance

    NARCIS (Netherlands)

    Slik, J.W.F.; Beek, van M.; Bernard, C.; Bongers, F.; Breman, F.C.; Cannon, C.H.; Sidiyasa, K.

    2011-01-01

    Large parts of the everwet tropics have been burned, leaving many unburned–burned forest edges. Here we studied a Bornean forest edge to determine: (1) how unburned and burned forest differ in vegetation structure, diversity, composition and plant functional traits 7 yr after fire, and (2) if these

  12. Seven-Year-Olds Allocate Attention Like Adults Unless Working Memory Is Overloaded

    Science.gov (United States)

    Cowan, Nelson; Morey, Candice C.; AuBuchon, Angela M.; Zwilling, Christopher E.; Gilchrist, Amanda L.

    2010-01-01

    Previous studies have indicated that visual working memory performance increases with age in childhood, but it is not clear why. One main hypothesis has been that younger children are less efficient in their attention; specifically, they are less able to exclude irrelevant items from working memory to make room for relevant items. We examined this…

  13. A Seven-Year Review of Accidental Kerosene Poisoning in Children ...

    African Journals Online (AJOL)

    Background: Accidental ingestion of kerosene is a potential source of morbidity and mortality in children. The objectives of the study are to determine to magnitude of the problem and proffer feasible solutions to reduce the frequency of occurrence. Methodology: The medical records of all cases of kerosene poisoning ...

  14. Seven-year clinical evaluation of painful cracked teeth restored with a direct composite restoration.

    NARCIS (Netherlands)

    Opdam, N.J.M.; Roeters, F.J.M.; Loomans, B.A.C.; Bronkhorst, E.M.

    2008-01-01

    The purpose of this study was to investigate long-term clinical effectiveness of treating painful cracked teeth with a direct bonded composite resin restoration. The hypothesis tested was that cracked teeth treated with or without cuspal coverage showed the same performance. Forty-one patients

  15. Late Career Decision-Making: A Qualitative Panel Study

    NARCIS (Netherlands)

    Wilmar Schaufeli; Annet de Lange; Juhani Ilmarinen; Per Erik Solem; Trude Furunes; Reidar Mykletun; Astri Syse

    2015-01-01

    The aim of this longitudinal qualitative interview study (3 waves of interviews) was to examine the nature of older workers’ late career decision-making processes, including the main drivers and obstacles for prolonging working life or retiring. Late career decision-making is regarded as a process

  16. Preliminary study on flakeboard panels made from aspen slash wood

    Science.gov (United States)

    Yan Yu; Alan Rudie; Zhiyong Cai

    2010-01-01

    The disposal of forest-thinning residue is one of the major problems for sustainable forest management. The purpose of this study was to investigate the technical possibility of utilizing aspen logging slash wood with a diameter ranging from 50 to 76 mm for flakeboard production. Influences of weight ratio between slash wood and commercial flakes on the selected...

  17. Seven Years Cognitive Functioning and Early Assessment in Extremely Low Birth Weight Children.

    Science.gov (United States)

    Squarza, Chiara; Picciolini, Odoardo; Gardon, Laura; Ravasi, Maura; Giannì, Maria L; Porro, Matteo; Bonzini, Matteo; Gangi, Silvana; Mosca, Fabio

    2017-01-01

    Infants born preterm are at high risk for the onset of cognitive dysfunctions at school age. The aim of this study was to investigate the association between early neurodevelopmental assessment and the risk of adverse cognitive outcome in extremely low birth weight children. We enrolled all newborns (January 2002 - April 2007) consecutively admitted to our Institution, with a birthweight age using the Griffiths Mental Development Scales Revised. The same children were re-assessed at school age through the Wechsler Intelligence Scale for Children. Children with impaired Griffiths General Quotient (i.e., age showed a significantly lower Full Scale Intelligence Quotient at 7 years of chronological age when compared to children who scored in the normal range at 1 year ( p Eye and Hand Coordination Sub-quotients were specifically associated with poorer Performance or Verbal Intelligence Quotients, respectively ( p age. Larger confirmation studies are needed.

  18. A Balint-inspired reflective forum in oncology for medical residents: main themes during seven years.

    Science.gov (United States)

    Salander, Pär; Sandström, Maria

    2014-10-01

    Reflection groups for clinicians, often called Balint groups, are a way of refining professional competence in health care. This study presents a model for reflective practice in a group setting and describes the kinds of troublesome cases that medical residents are concerned about. From 2005 to 2012 a Balint-inspired reflective forum has been a part of the academic seminar program for physicians in training in a Department of Oncology at a Swedish university. The present study is focused on all 63 cases presented in the forum. The cases were categorized into three kinds of challenges: Communication challenges in the patient-physician relationship, Communication challenges in organizational matters, and Communication challenges with close relatives of the patient. The study tells us something about the vulnerability of being a medical resident and the identified challenges have bearings on medical education curricula as well as on how the training of junior physicians is organized. The cases are contextual and multifaceted, and a forum of this kind might therefore be regarded as a potential way to develop professional competence and to refine communication in clinical practice. A structured evaluation of the forum would be valuable. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. A panel study on the relationship between corruption and government size

    OpenAIRE

    Go, Kotera; Okada, Keisuke; Samreth, Sovannroeun

    2010-01-01

    Using panel data from 1996 to 2005, this paper shows that the effect of government size on corruption is positive at a low level of democracy, but it is negative at a high level. This finding could fill the gaps in previous studies whose findings on the relationship between corruption and government size are controversial.

  20. Air pollution and respiratory health of children: the PEACE panel study in Berlin., Germany.

    NARCIS (Netherlands)

    Englert, N.; Babisch, W.; Hoek, G.

    1998-01-01

    As part of a multicentre European investigation on effects of short-term changes in urban air pollution on the respiratory health of children with chronic respiratory symptoms (the Pollution Effects on Asthmatic Children in Europe (PEACE) project),a panel study was carried out in two locations in

  1. Finite Element Studies on Free Vibration of Laminated Composite Cylindrical Skew Panels

    Directory of Open Access Journals (Sweden)

    Srinivasa Chikkol Venkateshappa

    2014-01-01

    Full Text Available This paper presents the finite element studies made on free vibration of isotropic and laminated composite cylindrical skew panels. A finite element analysis is performed using CQUAD4 and CQUAD8 elements of MSC/NASTRAN software. The effects of the panel angle, skew angle, aspect ratio, and length-to-thickness-ratio on fundamental natural frequency of vibration of isotropic cylindrical skew panels are studied. The effects of additional parameters such as fiber orientation angle, numbers of layers (keeping total thickness constant, and laminate stacking sequence on the fundamental frequency of vibration of antisymmetric composite laminates have also been studied. During validation and convergence study, it is found that the CQUAD8 element yields more accurate results than the CQUAD4 element. Hence the CQUAD8 element has been employed for the remaining part of the investigation. The fundamental frequency is found to increase with the panel angle and skew angle. The variation of the fundamental frequency with the number of layers is not appreciable when the number of layers is greater than about 6. It is also seen that the boundary conditions have significant influence on the fundamental frequency.

  2. Effects of attitude dissimilarity and time on social integration : A longitudinal panel study

    NARCIS (Netherlands)

    Van der Vegt, G.S.

    2002-01-01

    A longitudinal panel study in 25 work groups of elementary school teachers examined the effect of attitudinal dissimilarity and time on social integration across a 9-month period. In line with the prediction based on both the similarity-attraction approach and social identity theory, cross-lagged

  3. Sixty-Seven Years of Land-Use Change in Southern Costa Rica

    Science.gov (United States)

    Zahawi, Rakan A.; Duran, Guillermo; Kormann, Urs

    2015-01-01

    Habitat loss and fragmentation of forests are among the biggest threats to biodiversity and associated ecosystem services in tropical landscapes. We use the vicinity of the Las Cruces Biological Station in southern Costa Rica as a regional case study to document seven decades of land-use change in one of the most intensively studied sites in the Neotropics. Though the premontane wet forest was largely intact in 1947, a wave of immigration in 1952 initiated rapid changes over a short period. Overall forest cover was reduced during each time interval analyzed (1947–1960, 1960–1980, 1980–1997, 1997–2014), although the vast majority of forest loss (>90%) occurred during the first two time intervals (1947–1960, 1960–1980) with an annual deforestation rate of 2.14% and 3.86%, respectively. The rate dropped to 100 km of linear strips of vegetation within a 3 km radius of the station, which may facilitate landscape-level movement for some species. Despite the extent of forest loss, a substantial number of regional landscape-level studies over the past two decades have demonstrated the persistence of many groups of organisms such as birds and mammals. Nonetheless, the continued decline in the quantity and quality of remaining habitat (~30% of remaining forest is secondary), as well as the threat of an extinction debt (or time lag in species loss), may result in the extirpation of additional species if more proactive conservation measures are not taken to reverse current trends–a pattern that reflects many other tropical regions the world over. PMID:26599325

  4. Diverse Effects of a Seven-Year Experimental Grassland Fragmentation on Major Invertebrate Groups.

    Science.gov (United States)

    Braschler, Brigitte; Baur, Bruno

    2016-01-01

    Habitat fragmentation is a major driver of biodiversity loss, but observed effects vary and may depend on the group examined. Time since fragmentation may explain some differences between taxonomical groups, as some species and thus species composition respond with a delay to changes in their environment. Impacts of drivers of global change may thus be underestimated in short-term studies. In our study we experimentally fragmented nutrient-poor dry calcareous grasslands and studied the response of species richness, individual density and species composition of various groups of invertebrates (gastropods, ants, ground beetles, rove beetles, orthoptera, spiders, woodlice) in 12 small (1.5 m * 1.5 m) and 12 large (4.5 m * 4.5 m) fragments and their corresponding control plots after 7 years. We further examined responses to fragmentation in relation to body size and habitat preferences. Responses to fragmentation varied between taxonomical groups. While spider species richness and individual density were lower in fragments, the opposite was true for an orthopteran species and woodlice. Species composition and β-diversity differed between fragments and control plots for some groups. However, the interaction treatment*plot size was rarely significant. Species with high occupancy rates in undisturbed control plots responded more negatively to the fragmentation, while species with large body size were relatively more abundant in fragments in some groups. No effect of the fragmentation was found for ants, which may have the longest lag times because of long-lived colonies. However, relationships between abundance and the species' preferences for environmental factors affected by edge effects indicate that ant diversity too may be affected in the longer-term. Our results show the importance of considering different groups in conservation management in times of widespread fragmentation of landscapes. While species richness may respond slowly, changes in abundance related to

  5. Diverse Effects of a Seven-Year Experimental Grassland Fragmentation on Major Invertebrate Groups.

    Directory of Open Access Journals (Sweden)

    Brigitte Braschler

    Full Text Available Habitat fragmentation is a major driver of biodiversity loss, but observed effects vary and may depend on the group examined. Time since fragmentation may explain some differences between taxonomical groups, as some species and thus species composition respond with a delay to changes in their environment. Impacts of drivers of global change may thus be underestimated in short-term studies. In our study we experimentally fragmented nutrient-poor dry calcareous grasslands and studied the response of species richness, individual density and species composition of various groups of invertebrates (gastropods, ants, ground beetles, rove beetles, orthoptera, spiders, woodlice in 12 small (1.5 m * 1.5 m and 12 large (4.5 m * 4.5 m fragments and their corresponding control plots after 7 years. We further examined responses to fragmentation in relation to body size and habitat preferences. Responses to fragmentation varied between taxonomical groups. While spider species richness and individual density were lower in fragments, the opposite was true for an orthopteran species and woodlice. Species composition and β-diversity differed between fragments and control plots for some groups. However, the interaction treatment*plot size was rarely significant. Species with high occupancy rates in undisturbed control plots responded more negatively to the fragmentation, while species with large body size were relatively more abundant in fragments in some groups. No effect of the fragmentation was found for ants, which may have the longest lag times because of long-lived colonies. However, relationships between abundance and the species' preferences for environmental factors affected by edge effects indicate that ant diversity too may be affected in the longer-term. Our results show the importance of considering different groups in conservation management in times of widespread fragmentation of landscapes. While species richness may respond slowly, changes in

  6. Sixty-Seven Years of Land-Use Change in Southern Costa Rica.

    Directory of Open Access Journals (Sweden)

    Rakan A Zahawi

    Full Text Available Habitat loss and fragmentation of forests are among the biggest threats to biodiversity and associated ecosystem services in tropical landscapes. We use the vicinity of the Las Cruces Biological Station in southern Costa Rica as a regional case study to document seven decades of land-use change in one of the most intensively studied sites in the Neotropics. Though the premontane wet forest was largely intact in 1947, a wave of immigration in 1952 initiated rapid changes over a short period. Overall forest cover was reduced during each time interval analyzed (1947-1960, 1960-1980, 1980-1997, 1997-2014, although the vast majority of forest loss (>90% occurred during the first two time intervals (1947-1960, 1960-1980 with an annual deforestation rate of 2.14% and 3.86%, respectively. The rate dropped to 100 km of linear strips of vegetation within a 3 km radius of the station, which may facilitate landscape-level movement for some species. Despite the extent of forest loss, a substantial number of regional landscape-level studies over the past two decades have demonstrated the persistence of many groups of organisms such as birds and mammals. Nonetheless, the continued decline in the quantity and quality of remaining habitat (~30% of remaining forest is secondary, as well as the threat of an extinction debt (or time lag in species loss, may result in the extirpation of additional species if more proactive conservation measures are not taken to reverse current trends-a pattern that reflects many other tropical regions the world over.

  7. Clinical profile and impact on quality of life: Seven years experience with patients of alopecia areata

    Directory of Open Access Journals (Sweden)

    Nawaf Al-Mutairi

    2011-01-01

    Full Text Available Background: Alopecia areata (AA is the most common cause of localized, non-scarring alopecia. Stress and other psychological factors have been implicated in the causation of the disease, and it is also found to alter the course of the disease process. Unfortunately no one has studied the impact of AA on the quality of life, which includes the social life of the patients. Aim: To study the clinical profile and impact of alopecia areata on the quality of life, including the social life of adult patients with severe forms of the disease. Methods: The present study determined the clinical pattern of AA and its impact on the quality of life (QOL in all the patients with severe forms of alopecia areata attending the Dermatology Outpatient Department. Results: The male : female ratio was 1.86 : 1. Most (58.03% of the patients were between 21 and 40 years of age. Almost 40% of the patients had associated systemic disease or other dermatological disorders. A family history of AA was found in 593 (20.02% of the patients. Nail changes were observed in 297 (10% of the patients. There were significant differences between the mean Dermatology Life Quality Index (DLQI score in cases with severe forms of AA and controls ( p0 < 0.001. Conclusions: Severe forms of alopecia areata had a major impact on the psychosocial well-being of the patients. These individuals had to be treated early, and they required more than just prescription drugs. Educational and psychological support in addition to medical therapy for AA could improve their long-term physical outcomes.

  8. Seven years' experience with Cryptosporidium parvum in Guinea-Bissau, West Africa

    DEFF Research Database (Denmark)

    Perch, M; Sodemann, Morten; Jakobsen, M S

    2001-01-01

    In community-based studies conducted from 1991 to 1997 in Guinea-Bissau, West Africa, stool specimens from children aged less than 5 years with diarrhoea were routinely examined for enteric parasites. Cryptosporidium parvum, found in 7.7% of 4,922 samples, was the second most common parasite, exc...... consistently at the beginning of or just before the rainy seasons, May through July. By contrast, no seasonality was found for the enteric parasites Giardia lamblia or Entamoeba histolytica. We conclude that Cryptosporidium parvum is an important pathogen in children with diarrhoea....

  9. Single-port laparoscopy in gynecologic oncology: seven years of experience at a single institution.

    Science.gov (United States)

    Moulton, Laura; Jernigan, Amelia M; Carr, Caitlin; Freeman, Lindsey; Escobar, Pedro F; Michener, Chad M

    2017-11-01

    Single-port laparoscopy has gained popularity within minimally invasive gynecologic surgery for its feasibility, cosmetic outcomes, and safety. However, within gynecologic oncology, there are limited data regarding short-term adverse outcomes and long-term hernia risk in patients undergoing single-port laparoscopic surgery. The objective of the study was to describe short-term outcomes and hernia rates in patients after single-port laparoscopy in a gynecologic oncology practice. A retrospective, single-institution study was performed for patients who underwent single-port laparoscopy from 2009 to 2015. A univariate analysis was performed with χ 2 tests and Student t tests; Kaplan-Meier and Cox proportional hazards determined time to hernia development. A total of 898 patients underwent 908 surgeries with a median follow-up of 37.2 months. The mean age and body mass index were 55.7 years and 29.6 kg/m 2 , respectively. The majority were white (87.9%) and American Society of Anesthesiologists class II/III (95.5%). The majority of patients underwent surgery for adnexal masses (36.9%) and endometrial hyperplasia/cancer (37.3%). Most women underwent hysterectomy (62.7%) and removal of 1 or both fallopian tubes and/or ovaries (86%). Rate of adverse outcomes within 30 days, including reoperation (0.1%), intraoperative injury (1.4%), intensive care unit admission (0.4%), venous thromboembolism (0.3%), and blood transfusion, were low (0.8%). The rate of urinary tract infection was 2.8%; higher body mass index (P = .02), longer operative time (P = .02), smoking (P = .01), hysterectomy (P = .01), and cystoscopy (P = .02) increased the risk. The rate of incisional cellulitis was 3.5%. Increased estimated blood loss (P = .03) and endometrial cancer (P = .02) were independent predictors of incisional cellulitis. The rate for surgical readmissions was 3.4%; higher estimated blood loss (P = .03), longer operative time (P = .02), chemotherapy alone (P = .03), and

  10. Seven years of gamma-ray spectrometry interlaboratory comparisons in Switzerland

    International Nuclear Information System (INIS)

    Bailat, Claude; Buchillier, Thierry; Caffari, Yvan; Nedjadi, Youcef; Spring, Philippe; Estier, Sybille; Bochud, Francois

    2010-01-01

    Since the 1990s, regular comparisons of gamma-ray spectrometry in Switzerland were organized to improve laboratory abilities to measure the radioactivity in the environment and food stuffs at typical routine levels. The activity concentration of the test samples and the evaluation of the associated uncertainties remained each year the main required test result. Over the years, the comparisons used certified reference solutions as well as environmental samples. The aim of this study is to research the effect of the comparisons on measurement quality. An analysis of the seven last interlaboratory comparisons revealed that the Swiss measurement capability is up to date. In addition, the results showed that the participants now have an improved evaluation of the uncertainties associated with their measurement.

  11. Seven years with the Swift Supergiant Fast X-ray Transients project

    Science.gov (United States)

    Romano, P.

    2015-09-01

    Supergiant Fast X-ray Transients (SFXTs) are HMXBs with OB supergiant companions. I review the results of the Swift SFXT project, which since 2007 has been exploiting Swift's capabilities in a systematic study of SFXTs and supergiant X-ray binaries (SGXBs) by combining follow-ups of outbursts, when detailed broad-band spectroscopy is possible, with long-term monitoring campaigns, when the out-of-outburst fainter states can be observed. This strategy has led us to measure their duty cycles as a function of luminosity, to extract their differential luminosity distributions in the soft X-ray domain, and to compare, with unprecedented detail, the X-ray variability in these different classes of sources. I also discuss the ;seventh year crisis;, the challenges that the recent Swift observations are making to the prevailing models attempting to explain the SFXT behavior.

  12. Seven years' experience with Cryptosporidium parvum in Guinea-Bissau, West Africa

    DEFF Research Database (Denmark)

    Perch, M; Sodemann, Morten; Jakobsen, M S

    2001-01-01

    In community-based studies conducted from 1991 to 1997 in Guinea-Bissau, West Africa, stool specimens from children aged less than 5 years with diarrhoea were routinely examined for enteric parasites. Cryptosporidium parvum, found in 7.7% of 4,922 samples, was the second most common parasite......, exceeded only by Giardia lamblia which was found in 14.8% of the samples. The highest prevalence of cryptosporidium was found in children aged 6-11 months, whereas the prevalence of other enteric parasites increased with age. Cryptosporidiosis showed a marked seasonal variation, with peak prevalences found...... consistently at the beginning of or just before the rainy seasons, May through July. By contrast, no seasonality was found for the enteric parasites Giardia lamblia or Entamoeba histolytica. We conclude that Cryptosporidium parvum is an important pathogen in children with diarrhoea....

  13. Seven-year clinical evaluation of painful cracked teeth restored with a direct composite restoration.

    Science.gov (United States)

    Opdam, Niek J M; Roeters, Joost J M; Loomans, Bas A C; Bronkhorst, Ewald M

    2008-07-01

    The purpose of this study was to investigate long-term clinical effectiveness of treating painful cracked teeth with a direct bonded composite resin restoration. The hypothesis tested was that cracked teeth treated with or without cuspal coverage showed the same performance. Forty-one patients attended a dental practice with a painful cracked tooth that was restored with a direct composite resin restoration. Twenty teeth were restored without and 21 with cuspal coverage. After 7 years, 40 teeth could be evaluated. Three teeth without cuspal coverage needed an endodontic treatment, of which 2 failed as a result of fracture. No significant differences were found for tooth or pulp survival. Three more repairable restoration failures were recorded. Mean annual failure rate of restorations without cuspal coverage was 6%; no failures in restorations with cuspal coverage occurred (P = .009). A direct bonded composite resin restoration can be a successful treatment for a cracked tooth.

  14. Seven Years Cognitive Functioning and Early Assessment in Extremely Low Birth Weight Children

    Directory of Open Access Journals (Sweden)

    Chiara Squarza

    2017-07-01

    Full Text Available Infants born preterm are at high risk for the onset of cognitive dysfunctions at school age. The aim of this study was to investigate the association between early neurodevelopmental assessment and the risk of adverse cognitive outcome in extremely low birth weight children. We enrolled all newborns (January 2002 – April 2007 consecutively admitted to our Institution, with a birthweight < 1000 g. Exclusion criteria were genetic abnormalities, severe neurofunctional impairment, and/or neurosensory disabilities. Ninety-nine children were assessed at 1 year of corrected age using the Griffiths Mental Development Scales Revised. The same children were re-assessed at school age through the Wechsler Intelligence Scale for Children. Children with impaired Griffiths General Quotient (i.e., <1 SD at 1 year of corrected age showed a significantly lower Full Scale Intelligence Quotient at 7 years of chronological age when compared to children who scored in the normal range at 1 year (p < 0.01. Considering the Griffiths Sub-quotients separately, a poor score in the Performance or in the Personal-Social Sub-quotients at 1 year was associated with significantly worse cognitive outcomes both in the Verbal and in the Performance Intelligence Quotients at 7 years (p < 0.01 and p < 0.05, respectively. A score <1 SD in the Locomotor or in the Eye and Hand Coordination Sub-quotients were specifically associated with poorer Performance or Verbal Intelligence Quotients, respectively (p < 0.05. Our findings suggest that a poor score on the Griffiths Scales at 1 year is associated with a higher risk of cognitive impairment at school age. Larger confirmation studies are needed.

  15. Climate impact on airborne particulate matter concentrations in California using seven year analysis periods

    Science.gov (United States)

    Mahmud, A.; Hixson, M.; Hu, J.; Zhao, Z.; Chen, S.-H.; Kleeman, M. J.

    2010-11-01

    The effect of global climate change on the annual average concentration of fine particulate matter (PM2.5) in California was studied using a climate-air quality modeling system composed of global through regional models. Output from the NCAR/DOE Parallel Climate Model (PCM) generated under the "business as usual" global emissions scenario was downscaled using the Weather Research and Forecasting (WRF) model followed by air quality simulations using the UCD/CIT airshed model. The system represents major atmospheric processes acting on gas and particle phase species including meteorological effects on emissions, advection, dispersion, chemical reaction rates, gas-particle conversion, and dry/wet deposition. The air quality simulations were carried out for the entire state of California with a resolution of 8-km for the years 2000-2006 (present climate with present emissions) and 2047-2053 (future climate with present emissions). Each of these 7-year analysis periods was analyzed using a total of 1008 simulated days to span a climatologically relevant time period with a practical computational burden. The 7-year windows were chosen to properly account for annual variability with the added benefit that the air quality predictions under the present climate could be compared to actual measurements. The climate-air quality modeling system successfully predicted the spatial pattern of present climate PM2.5 concentrations in California but the absolute magnitude of the annual average PM2.5 concentrations were under-predicted by ~4-39% in the major air basins. The majority of this under-prediction was caused by excess ventilation predicted by PCM-WRF that should be present to the same degree in the current and future time periods so that the net bias introduced into the comparison is minimized. Surface temperature, relative humidity (RH), rain rate, and wind speed were predicted to increase in the future climate while the ultra violet (UV) radiation was predicted to decrease

  16. Climate impact on airborne particulate matter concentrations in California using seven year analysis periods

    Directory of Open Access Journals (Sweden)

    A. Mahmud

    2010-11-01

    Full Text Available The effect of global climate change on the annual average concentration of fine particulate matter (PM2.5 in California was studied using a climate-air quality modeling system composed of global through regional models. Output from the NCAR/DOE Parallel Climate Model (PCM generated under the "business as usual" global emissions scenario was downscaled using the Weather Research and Forecasting (WRF model followed by air quality simulations using the UCD/CIT airshed model. The system represents major atmospheric processes acting on gas and particle phase species including meteorological effects on emissions, advection, dispersion, chemical reaction rates, gas-particle conversion, and dry/wet deposition. The air quality simulations were carried out for the entire state of California with a resolution of 8-km for the years 2000–2006 (present climate with present emissions and 2047–2053 (future climate with present emissions. Each of these 7-year analysis periods was analyzed using a total of 1008 simulated days to span a climatologically relevant time period with a practical computational burden. The 7-year windows were chosen to properly account for annual variability with the added benefit that the air quality predictions under the present climate could be compared to actual measurements. The climate-air quality modeling system successfully predicted the spatial pattern of present climate PM2.5 concentrations in California but the absolute magnitude of the annual average PM2.5 concentrations were under-predicted by ~4–39% in the major air basins. The majority of this under-prediction was caused by excess ventilation predicted by PCM-WRF that should be present to the same degree in the current and future time periods so that the net bias introduced into the comparison is minimized.

    Surface temperature, relative humidity (RH, rain rate, and wind speed were predicted to increase in the future climate

  17. Seven year overview (2007—2013 of ethical transgressions by registered healthcare professionals in South Africa

    Directory of Open Access Journals (Sweden)

    Nico Nortje

    2016-10-01

    Full Text Available A move has taken place internationally in the delivery and “consumption” of health care where if clients and patients (health care consumers hold the opinion that the health care professionals/providers' behaviour has had a negative effect, impact or outcome on them, they may lodge a complaint with the relevant health professional regulatory body. Ethical transgressions of health care providers can generally be clustered into the following three categories: a Competence and conduct with clients (e.g. abandonment, sexual intimacies, dishonesty, disclosure of information; b Business practices (e.g. billing, reports, documentation; and c Professional practice (e.g. referral upon termination, obtaining appropriate potential employment opportunities, nonprofessional relationships.The primary objective of this study was to analyse the ethical transgressions of registered members of the twelve professional boards in the Health Professions Council of South Africa (HPCSA in the period 2007 to 2013. A mixed methods approach was followed in this study which specifically focused on a historical research approach. The results indicate that the boards with the highest number of transgressions per the registered practitioners were firstly the Medical and Dental practitioners, closely followed by the Optometry and Dispensing Opticians Board. The predominantly complaint made against members of both these boards was for fraudulent conduct (collectively totalling to 85% of all fraudulent cases during the period and included actions such as charging for non-rendered services, issuing false statements and submitting fraudulent medical aid claims. Cognisance needs to be taken that the South African public will increasingly demand better services and that since they are being better informed via the media of their rights and have access to a broader database of knowledge (rightly or wrongly so the internet practitioners' opinions will not necessarily be accepted

  18. Echocardiographic and Hemodynamic Predictors of Survival in Precapillary Pulmonary Hypertension: Seven-Year Follow-Up.

    Science.gov (United States)

    Grapsa, Julia; Pereira Nunes, Maria Carmo; Tan, Timothy C; Cabrita, Ines Zimbarra; Coulter, Taryn; Smith, Benjamin C F; Dawson, David; Gibbs, J Simon R; Nihoyannopoulos, Petros

    2015-06-01

    In this study, we looked at the prognostic value of echocardiographic and hemodynamic measures in a large cohort of patients with precapillary pulmonary hypertension before and after initiation of treatment. Data were collected prospectively in a cohort of consecutive patients with precapillary pulmonary hypertension referred between 2002 and 2011. A range of clinical and echocardiographic variables were collected and stored on a database to assess predictors of survival. Invasive hemodynamic data including pulmonary artery pressure, pulmonary vascular resistance, capillary wedge pressure, and cardiac index were also obtained at baseline in all patients. Outcome was defined as mortality because of cardiovascular-related death. The study cohort comprised 777 patients (514 women) with precapillary pulmonary hypertension. A total of 195 (25%) died. In multivariable analysis, moderate or severe tricuspid regurgitation (hazard ratio [HR], 26.537; 95% confidence interval, 11.536-61.044; P<0.001), right ventricular myocardial performance index (HR, 3.421; 95% confidence interval, 1.777-6.584; P<0.001), and the presence of pericardial effusion (HR, 1.38; 95% confidence interval, 1.023-1.862; P=0.035) were independent predictors of mortality. High pulmonary vascular resistance and right atrial pressure by invasive hemodynamic measurements were independent predictors of mortality (HR, 1.084; 95% confidence interval, 1.041-1.130, and 1.079, respectively; 95% confidence interval, 1.049-1.111; P<0.001 for both), whereas patients with a higher cardiac index had better survival overall (HR, 0.384; 95% confidence interval, 0.307-0.481; P<0.001). Right ventricular dysfunction, moderate-severe tricuspid regurgitation, low cardiac index, and raised right atrial pressure were associated with poor survival for both pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertensive disease patients. The severity of tricuspid regurgitation, myocardial performance index

  19. Nonfunctioning Renal Allograft Embolization as an Alternative to Graft Nephrectomy: Report on Seven Years' Experience

    International Nuclear Information System (INIS)

    Atar, Eli; Belenky, Alexander; Neuman-Levin, Margalit; Yussim, A.; Bar-Nathan, Nathan; Bachar, Gil N.

    2003-01-01

    Purpose: Graft nephrectomy is the treatment of choice in patients with graft intolerance syndrome, but it is associated with high morbidity and mortality rates. Renal vascular embolization has been suggested as a possible alternative. The aim of this study was to evaluate the efficacy and safety of arterial embolization of these nonfunctioning transplanted kidneys. Methods: Twenty-six transplanted kidneys in 25 patients with irreversible renal graft rejection and graft intolerance who underwent arterial embolization at our center from August 1994 to April 2001 we reanalyzed for procedural success and long-term outcome. Embolization was performed with absolute alcohol or with polyvinyl alcohol (Ivalon) and coils. Results: Twenty-four of the 26 (92%) procedures were technically successful, but in one patient only partial occlusion of one of two renal arteries was achieved, and in another the renal artery was already completely occluded. There were two major complications: emphysematous pyelonephritis necessitating nephrectomy and groin abscess that was drained. Follow-up ranged from 8 to 84 months. Clinical success was achieved in 24 of the 26 procedures(92%), and only in one patient did embolization fail to relieve the symptoms, and nephrectomy was performed 3 months later. Conclusion: Renal vascular embolization is a simple, safe and effective technique for the treatment of nonfunctioning renal allografts associated with graft intolerance syndrome. We suggest that it be considered the treatment of choice

  20. A prospective evaluation of zirconia anterior partial fixed dental prostheses: Clinical results after seven years.

    Science.gov (United States)

    Solá-Ruíz, Maria Fernanda; Agustin-Panadero, Rubén; Fons-Font, Antonio; Labaig-Rueda, Carlos

    2015-06-01

    Because of the high mechanical strength of zirconium dioxide, the metal in fixed partial prostheses can now be replaced. However, the material is susceptible to aging or hydrothermal degradation and to chipping of the feldspathic veneer. The purpose of this prospective study was to evaluate the survival (without failure) and success (survival without any complication or failure) rate and clinical efficacy of anterior zirconia partial fixed dental prostheses. Twenty-seven anterior partial fixed dental prostheses of 3 to 6 units were fabricated. All participants were examined after 1 month and 6 months, then annually for 7 years. Three partial fixed dental prostheses failed and had to be removed: 2 because of secondary caries, which increased failure significantly (P=.001) and 1 because of severe chipping. Six partial fixed dental prostheses had complications: 2 debonded, 3 had chipping, and 1 had periapical pathology. All veneer porcelain fractures occurred in 6-unit fixed partial prostheses (P=.002). The clinical success rate was 88.8% after the 7-year follow-up. The clinical behavior of partial fixed dental prostheses with a zirconium dioxide core in the anterior region provides an adequate medium-term survival rate. The main cause of failure was secondary caries. The most frequent complication was chipping, which was directly related to the number of units of the prosthesis. Copyright © 2015 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  1. Detecting one-hundred-year environmental changes in Western China using seven-year repeat photography.

    Directory of Open Access Journals (Sweden)

    Huai Chen

    Full Text Available Due to its diverse, wondrous plants and unique topography, Western China has drawn great attention from explorers and naturalists from the Western World. Among them, Ernest Henry Wilson (1876 -1930, known as 'Chinese' Wilson, travelled to Western China five times from 1899 to 1918. He took more than 1,000 photos during his travels. These valuable photos illustrated the natural and social environment of Western China a century ago. Since 1997, we had collected E.H. Wilson's old pictures, and then since 2004, along the expedition route of E.H. Wilson, we took 7 years to repeat photographing 250 of these old pictures. Comparing Wilson's photos with ours, we found an obvious warming trend over the 100 years, not only in specific areas but throughout the entire Western China. Such warming trend manifested in phenology changes, community shifts and melting snow in alpine mountains. In this study, we also noted remarkable vegetation changes. Out of 62 picture pairs were related to vegetation change, 39 indicated vegetation has changed to the better condition, 17 for degraded vegetation and six for no obvious change. Also in these photos at a century interval, we found not only rapid urbanization in Western China, but also the disappearance of traditional cultures. Through such comparisons, we should not only be amazed about the significant environmental changes through time in Western China, but also consider its implications for protecting environment while meeting the economic development beyond such changes.

  2. Summary of the results from the lunar orbiter laser altimeter after seven years in lunar orbit

    Science.gov (United States)

    Smith, David E.; Zuber, Maria T.; Neumann, Gregory A.; Mazarico, Erwan; Lemoine, Frank G.; Head, James W., III; Lucey, Paul G.; Aharonson, Oded; Robinson, Mark S.; Sun, Xiaoli; Torrence, Mark H.; Barker, Michael K.; Oberst, Juergen; Duxbury, Thomas C.; Mao, Dandan; Barnouin, Olivier S.; Jha, Kopal; Rowlands, David D.; Goossens, Sander; Baker, David; Bauer, Sven; Gläser, Philipp; Lemelin, Myriam; Rosenburg, Margaret; Sori, Michael M.; Whitten, Jennifer; Mcclanahan, Timothy

    2017-02-01

    In June 2009 the Lunar Reconnaissance Orbiter (LRO) spacecraft was launched to the Moon. The payload consists of 7 science instruments selected to characterize sites for future robotic and human missions. Among them, the Lunar Orbiter Laser Altimeter (LOLA) was designed to obtain altimetry, surface roughness, and reflectance measurements. The primary phase of lunar exploration lasted one year, following a 3-month commissioning phase. On completion of its exploration objectives, the LRO mission transitioned to a science mission. After 7 years in lunar orbit, the LOLA instrument continues to map the lunar surface. The LOLA dataset is one of the foundational datasets acquired by the various LRO instruments. LOLA provided a high-accuracy global geodetic reference frame to which past, present and future lunar observations can be referenced. It also obtained high-resolution and accurate global topography that were used to determine regions in permanent shadow at the lunar poles. LOLA further contributed to the study of polar volatiles through its unique measurement of surface brightness at zero phase, which revealed anomalies in several polar craters that may indicate the presence of water ice. In this paper, we describe the many LOLA accomplishments to date and its contribution to lunar and planetary science.

  3. Macrophyte distribution and ecological status of the Turiec River (Slovakia: Changes after seven years

    Directory of Open Access Journals (Sweden)

    Hrivnák R.

    2009-01-01

    Full Text Available Characteristics of diversity, abundance, distribution, and ecological status of aquatic macrophytes were observed in 2000 and 2007 on a circa 4.5 km long section of the Turiec River using Kohler's method. In comparison to 2000, the total number of macrophytes in 2007 increased markedly (from 25 to 35, although only the numbers of amphi­phytes and helophytes were changed substantially. The number of hydrophytes increased from 11 to 12; an invasive, Elodea canadenis, was the only new species. The relative plant mass of hydrophytes represents the bulk of all recorded species (95 and 80% in 2000 and 2007, respectively, and it was changed for most hydrophytes. The most significant changes were detected for Myriophyllum spicatum (decrease, filamentous algae (decrease, and Potamogeton crispus (increase. In 2007, the mean mass total (MMT sum of hydrophytes decreased from 16.46 to 14.5. On the other hand, the MMTsum of amphiphytes and helophytes doubled in value (7.4 and 14.1 in 2000 and 2007, respectively. Within hydrophytes, Batrachium species (including B. aquatile and B. trichophyllum, Myriophyllum spicatum, and Potamogeton crispus were ubiquitous (distribution ratio d > 0.5 in 2000, whereas in 2007 only Batrachium species and Potamogeton crispus were ubiquitous. At all times, Batrachium species were the most frequent species in the study area, and their abundance was relatively high (MMT> 2.5. A poor ecological status (MMP = 0.378 and MMP = 0.333 in 2000 and 2007, respectively of the surveyed river section was found in both years, but a slight decline of quality as determined on the basis of aquatic plants was observed after 7 years.

  4. Acute glomerulonephritis in children: A seven-year experience in a tertiary health center

    Directory of Open Access Journals (Sweden)

    Ali Güneş

    2012-09-01

    Full Text Available Objectives: The aim of this study was to examine clinicaland laboratory characteristics of children with AGN in atertiary university hospital.Materials and methods: Hospital records of childrenwhich hospitalized with AGN diagnosis in Pediatric NephrologyUnit, between 2004 and 2011, were retrospectivelyreviewed. Patients were divided into threesubgroups as age 10 years.Characteristics at hospital admission including, bloodpressure, diuresis state, serum urea, creatinine and electrolytelevels, complement factors C3 and C4, completeblood count and urine analysis results were recorded.Data about primary infection, treatments, disease courseand outcome were recorded and analyzed.Results: Totally 220 children (157 male, 71.2%; 63 female,28.8% were included. Probable etiological infectionswere tonsillopharyngitis in 133 (60.5%, pyodermain 12 (5.5%, other infections in 27 (12.2% children. In48 (21.8 children with AGN, no primary infection weredetected. Edema was found in 81.4% of patients, hypertensionin 73.6%, and pulmonary stasis in 22.6%. Low C3levels were found in 89.1%, azotemia in 45.9%, hematuriain 95.4%, nephritic proteinuria in 80.5%, and leukocyturiain 37.6% of patients. Diuresis was enabled withinone week in 82%. Additional vasodilators were given to45 (20.5% patients, and hemodialysis was performedto three. Except for frequency of low C3 (p=0.018 andanemia (p=0.006, no significant differences were foundin clinical and laboratory findings between age groups(p>0.05.Conclusions: No difference was found in clinical andlaboratory features of AGN based on age groups, excludinglow C3 and anemia frequency. J Clin Exp Invest 2012;3 (3: 357-362Key words: Acute glomerulonephritis, childhood, clinicalfindings, laboratory findings, age grops

  5. Technical and Clinical Outcomes Following Colonic Stenting: A Seven-Year Analysis of 268 Procedures.

    Science.gov (United States)

    Little, M W; Oakley, T; Briggs, J H; Sutcliffe, J A; Allouni, A K; Makris, G; Bratby, M J; Tapping, C R; Patel, R; Wigham, A; Anthony, S; Phillips-Hughes, J; Uberoi, R

    2016-10-01

    To assess the factors contributing to the technical and clinical success of colorectal stenting for large bowel obstruction. 268 cases of colonic stenting for large bowel obstruction were performed in 249 patients of mean age of 72 years (28-98) between 2006 and 2013. The majority of strictures were due to malignant disease, 244/268 (91 %). Diverticular strictures accounted for 24/268 (9 %). Overall technical success rate was 81 % (217/268), with a clinical success rate of 65 % (174/268). Duration of symptoms ranged from 0 to 180 days (mean 8 days). Technical success rate was seen to decrease with increasing symptom duration. For symptom duration of less than 1 week, technical success was 85.4 % (181/212) versus 69.6 % (39/56) for those with symptoms of greater than a week (p < 0.05). Clinical success rates fell from 71.3 % (107/150) to 59.3 % (70/118) (p < 0.05) when attempting to stent lesions of greater than 5 cm. There was also a significant reduction in clinical success when stenting lesions on a bend rather than a straight segment of colon 75.7 % (109/144) versus 59.7 % (74/124) (p < 0.05). A total of 20 (7.46 %) perforations were identified during the study. Stent migration occurred in 6.6 % of cases. In-stent stenosis occurred in 3.3 %. The overall 30-day all cause mortality rate was 9 %. Lesion size, location and duration of obstructive symptoms are statistically significant determinants of patient outcome. These factors could be used to advise patient selection for colonic stenting or direct progression to surgical intervention.

  6. Technical and Clinical Outcomes Following Colonic Stenting: A Seven-Year Analysis of 268 Procedures

    International Nuclear Information System (INIS)

    Little, M. W.; Oakley, T.; Briggs, J. H.; Sutcliffe, J. A.; Allouni, A. K.; Makris, G.; Bratby, M. J.; Tapping, C. R.; Patel, R.; Wigham, A.; Anthony, S.; Phillips-Hughes, J.; Uberoi, R.

    2016-01-01

    AimsTo assess the factors contributing to the technical and clinical success of colorectal stenting for large bowel obstruction.Methodology268 cases of colonic stenting for large bowel obstruction were performed in 249 patients of mean age of 72 years (28–98) between 2006 and 2013. The majority of strictures were due to malignant disease, 244/268 (91 %). Diverticular strictures accounted for 24/268 (9 %).ResultsOverall technical success rate was 81 % (217/268), with a clinical success rate of 65 % (174/268). Duration of symptoms ranged from 0 to 180 days (mean 8 days). Technical success rate was seen to decrease with increasing symptom duration. For symptom duration of less than 1 week, technical success was 85.4 % (181/212) versus 69.6 % (39/56) for those with symptoms of greater than a week (p < 0.05). Clinical success rates fell from 71.3 % (107/150) to 59.3 % (70/118) (p < 0.05) when attempting to stent lesions of greater than 5 cm. There was also a significant reduction in clinical success when stenting lesions on a bend rather than a straight segment of colon 75.7 % (109/144) versus 59.7 % (74/124) (p < 0.05). A total of 20 (7.46 %) perforations were identified during the study. Stent migration occurred in 6.6 % of cases. In-stent stenosis occurred in 3.3 %. The overall 30-day all cause mortality rate was 9 %.ConclusionLesion size, location and duration of obstructive symptoms are statistically significant determinants of patient outcome. These factors could be used to advise patient selection for colonic stenting or direct progression to surgical intervention.

  7. Technical and Clinical Outcomes Following Colonic Stenting: A Seven-Year Analysis of 268 Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Little, M. W.; Oakley, T.; Briggs, J. H.; Sutcliffe, J. A.; Allouni, A. K.; Makris, G.; Bratby, M. J.; Tapping, C. R.; Patel, R.; Wigham, A.; Anthony, S.; Phillips-Hughes, J.; Uberoi, R., E-mail: Raman.uberoi@ouh.nhs.uk [Oxford University Hospitals NHS Foundation Trust, Department of Interventional Radiology, John Radcliffe Hospital (United Kingdom)

    2016-10-15

    AimsTo assess the factors contributing to the technical and clinical success of colorectal stenting for large bowel obstruction.Methodology268 cases of colonic stenting for large bowel obstruction were performed in 249 patients of mean age of 72 years (28–98) between 2006 and 2013. The majority of strictures were due to malignant disease, 244/268 (91 %). Diverticular strictures accounted for 24/268 (9 %).ResultsOverall technical success rate was 81 % (217/268), with a clinical success rate of 65 % (174/268). Duration of symptoms ranged from 0 to 180 days (mean 8 days). Technical success rate was seen to decrease with increasing symptom duration. For symptom duration of less than 1 week, technical success was 85.4 % (181/212) versus 69.6 % (39/56) for those with symptoms of greater than a week (p < 0.05). Clinical success rates fell from 71.3 % (107/150) to 59.3 % (70/118) (p < 0.05) when attempting to stent lesions of greater than 5 cm. There was also a significant reduction in clinical success when stenting lesions on a bend rather than a straight segment of colon 75.7 % (109/144) versus 59.7 % (74/124) (p < 0.05). A total of 20 (7.46 %) perforations were identified during the study. Stent migration occurred in 6.6 % of cases. In-stent stenosis occurred in 3.3 %. The overall 30-day all cause mortality rate was 9 %.ConclusionLesion size, location and duration of obstructive symptoms are statistically significant determinants of patient outcome. These factors could be used to advise patient selection for colonic stenting or direct progression to surgical intervention.

  8. Uterine rupture: A seven year review at a tertiary care hospital in New Delhi, India

    Directory of Open Access Journals (Sweden)

    Maruti Sinha

    2016-01-01

    Full Text Available Objective: To identify the obstetric risk factors, incidence, and causes of uterine rupture, management modalities, and the associated maternal and perinatal morbidity and mortality in one of the largest tertiary level women care hospital in Delhi. Materials and Methods: A 7-year retrospective analysis of 47 cases of uterine rupture was done. The charts of these patients were analyzed and the data regarding demographic characteristics, clinical presentation, risk factors, management, operative findings, maternal and fetal outcomes, and postoperative complications was studied. Results: The incidence of rupture was one in 1,633 deliveries (0.061%. The vast majority of patients had prior low transverse cesarean section (84.8%. The clinical presentation of the patients with rupture of the unscarred uterus was more dramatic with extensive tears compared to rupture with scarred uterus. The estimated blood loss ranged from 1,200 to 1,500 cc. Hemoperitoneum was identified in 95.7% of the patient and 83% of the patient underwent repair of rent with or without simultaneous tubal ligation. Subtotal hysterectomy was performed in five cases. There were no maternal deaths in our series. However, there were 32 cases of intrauterine fetal demise and five cases of stillbirths. Conclusions: Uterine rupture is a major contributor to maternal morbidity and neonatal mortality. Four major easily identifiable risk factors including history of prior cesarean section, grand multiparity, obstructed labor, and fetal malpresentations constitute 90% of cases of uterine rupture. Identification of these high risk women, prompt diagnosis, immediate transfer, and optimal management needs to be overemphasized to avoid adverse fetomaternal complications.

  9. Drinking and driving among Italian adolescents: Trends over seven years (2007-2013).

    Science.gov (United States)

    Siciliano, Valeria; Mezzasalma, Lorena; Scalese, Marco; Doveri, Cristina; Molinaro, Sabrina

    2016-03-01

    In recent years, increasing attention has been paid to the issue of driving under the influence of alcohol (DUI), especially among young people. The aims of the present study were (1) to analyse the trends of DUI, riding with a driver under influence of alcohol (RWDUI) and alcohol-related road crashes (A-rC) in a nationally representative sample of students in the period 2007-2013, (2) to assess how different drinking patterns were associated with DUI and RWDUI, (3) to evaluate other influential factors (such as gender, older siblings' and friends' behaviour with alcohol) on DUI and RWDUI. Data were drawn from the cross-sectional European School Survey Project on Alcohol and Other Drugs (ESPAD) carried out annually in Italy. The sample size ranged from 25,555 to 40,390 students (15-19 years old). Results were stratified for students trend for alcohol consumption was observed only in the younger group, a significant decrease in DUI [APC (annual percent change) -9.7 in the younger and -6.4 in the older group] and in RWDUI (APC -6.7 in the younger and -4.8 in the older group) was detected. A significant decreasing trend of A-rC was observed only in the older group (APC -3.4). Three specific drinking patterns were identified: "Drinking to Excess" (DE), "Drinking with Intoxication" (DI) and "Drinking but Not to Excess" (DNE). In both age groups, the DE pattern significantly increased the likelihood of DUI, whereas the DI pattern was negatively associated, and the DNE pattern was not associated. Different results were found for RWDUI: the DE and DI patterns where significantly associated with RWDUI, whereas the DNE pattern was negatively associated. Overall, illegal substance use, parental monitoring, peers' and siblings' influence were associated with DUI and RWDUI. The change in behaviour towards DUI and RWDUI suggests a cumulative effectiveness of current alcohol policies, although further actions (greater attention to social context, law enforcement, and promotion of

  10. Evaluation results after seven years of operation for the permanent Hellenic Seismological Network of Crete (HSNC).

    Science.gov (United States)

    Vallianatos, F.; Hloupis, G.; Papadopoulos, I.

    2012-04-01

    infrastructure that can provide data for aftershock studies can be initiated after a few hours. c) Real time algorithms for Early Warning Purposes. These include the rapid estimation of magnitude and epicentre after 5secs from the initial P-wave arrival. Acknowledgements. This work was supported in part by the ARCHIMEDES III Program of the Ministry of Education of Greece and the European Union in the framework of the project entitled "Intredisciplinary Multi-Scale Research of Earthquake Physics and Seismotectonics at the front of the Hellenic Arc (IMPACT ARC)"

  11. Metabolic Panel

    Science.gov (United States)

    A metabolic panel is a group of tests that measures different chemicals in the blood. These tests are usually done on ... and liver. There are two types: basic metabolic panel (BMP) and comprehensive metabolic panel (CMP). The BMP ...

  12. Energy efficiency and indoor thermal perception. A comparative study between radiant panel and portable convective heaters

    Energy Technology Data Exchange (ETDEWEB)

    Ali, Ahmed Hamza H.; Morsy, Mahmoud Gaber [Department of Mechanical Engineering, Faculty of Engineering, Assiut University, Assiut, 71516 (Egypt)

    2010-11-15

    This study investigates experimentally the thermal perception of indoor environment for evaluating the ability of radiant panel heaters to produce thermal comfort for space occupants as well as the energy consumption in comparison with conventional portable natural convective heaters. The thermal perception results show that, compared with conventional convection heater, a radiantly heated office room maintains a lower ambient air temperature while providing equal levels of thermal perception on the thermal dummy head as the convective heater and saves up to 39.1% of the energy consumption per day. However, for human subjects' vote experiments, the results show that for an environmentally controlled test room at outdoor environment temperatures of 0C and 5C, using two radiant panel heaters with a total capacity of 580 W leads to a better comfort sensation than the conventional portable natural convective heater with a 670 W capacity, with an energy saving of about 13.4%. In addition, for an outdoor environment temperature of 10C, using one radiant panel heater with a capacity of 290 W leads to a better comfort sensation than the conventional convection heater with a 670 W capacity, with an energy saving of about 56.7%. From the analytical results, it is found that distributing the radiant panel heater inside the office room, one on the wall facing the window and the other on the wall close to the window, provides the best operative temperature distribution within the room.

  13. An efficient model of an equipment loaded panel for active control design studies.

    Science.gov (United States)

    Aglietti, G S; Langley, R S; Rogers, E; Gabriel, S B

    2000-10-01

    An effective investigation of alternative control strategies for the reduction of vibration levels in satellite structures requires realistic, yet efficient, structural models to simulate the dynamics of the system. These models should include the effects of the sources, receivers, supporting structure, sensors, and actuators. In this paper, a modeling technique which meets these requirements is developed and some active control strategies are briefly investigated. The particular subject of investigation is an equipment-loaded panel and the equations of motion are derived using the Lagrange-Rayleigh-Ritz (LRR) approach. The various pieces of equipment on the panel are mounted on active or passive suspensions, and resonators are used to represent the internal dynamics of the mounted equipment. Control of the panel, which transmits vibrations from sources to receivers, is by means of piezoelectric patches and the excitation consists of dynamic loads acting on the equipment enclosures and/or directly on the panel. The control objective is to minimize the displacement at an arbitrary output location. The LRR model developed is verified against one produced by using the finite-element method. Finally, some initial controller design studies are undertaken to investigate and compare the effectiveness of different control strategies (e.g., minimization at the source, along the vibration path, or at the receiver).

  14. Study of thermosiphon and radiant panel passive heating systems for metal buildings

    Energy Technology Data Exchange (ETDEWEB)

    Biehl, F.A.; Schnurr, N.M.; Wray, W.O.

    1983-01-01

    A study of passive-heating systems appropriate for use on metal buildings is being conducted at Los Alamos National Laboratory for the Naval Civil Engineering Laboratory, Port Hueneme, California. The systems selected for study were chosen on the basis of their appropriateness for retrofit applications, although they are also suitable for new construction: simple radiant panels that communicate directly with the building interior and a backflow thermosiphon that provides heat indirectly.

  15. Integrated Thermal Treatment Systems study: US Department of Energy Internal Review Panel report

    Energy Technology Data Exchange (ETDEWEB)

    Cudahy, J.; Escarda, T.; Gimpel, R. [and others

    1995-04-01

    The U.S. Department of Energy`s (DOE) Office of Technology Development (OTD) commissioned two studies to uniformly evaluate nineteen thermal treatment technologies. These studies were called the Integrated Thermal Treatment System (ITTS) Phase I and Phase II. With the advice and guidance of the DOE Office of Environmental Management`s (EM`s) Mixed Waste Focus Group, OTD formed an ITTS Internal Review Panel, composed of scientists and engineers from throughout the DOE complex, the U.S. Environmental Protection Agency (EPA), the California EPA, and private experts. The Panel met from November 15-18, 1994, to review and comment on the ITTS studies, to make recommendations on the most promising thermal treatment systems for DOE mixed low level wastes (MLLW), and to make recommendations on research and development necessary to prove the performance of the technologies on MLLW.

  16. Integrated Thermal Treatment Systems study: US Department of Energy Internal Review Panel report

    International Nuclear Information System (INIS)

    Cudahy, J.; Escarda, T.; Gimpel, R.

    1995-04-01

    The U.S. Department of Energy's (DOE) Office of Technology Development (OTD) commissioned two studies to uniformly evaluate nineteen thermal treatment technologies. These studies were called the Integrated Thermal Treatment System (ITTS) Phase I and Phase II. With the advice and guidance of the DOE Office of Environmental Management's (EM's) Mixed Waste Focus Group, OTD formed an ITTS Internal Review Panel, composed of scientists and engineers from throughout the DOE complex, the U.S. Environmental Protection Agency (EPA), the California EPA, and private experts. The Panel met from November 15-18, 1994, to review and comment on the ITTS studies, to make recommendations on the most promising thermal treatment systems for DOE mixed low level wastes (MLLW), and to make recommendations on research and development necessary to prove the performance of the technologies on MLLW

  17. Assessment of effective doses due to 137 Cs and 90 Sr dietary intake seven years after Chernobyl accident

    International Nuclear Information System (INIS)

    Toader, Maria; Vasilache, R. A.

    1996-01-01

    During the first seven years elapsing from the Chernobyl accident, 137 Cs and 90 Sr concentrations in dietary intake and urinary excretion were determined for a group of 15 adult men. The mathematical functions for intake and excretion were deduced. The results were used to assess the the effective dose committed by Bucharest population and to obtain rough evaluation of the exceeding cancer risk due to internally deposited caesium and strontium. The effective dose committed due to caesium intake in all these years was 1077 μSv, while the dose committed due to strontium intake was 16 μSv to bone surface and 21 μSv to red marrow. Exceeding cancer risk derived from these doses was found to be negligible. There is no risk for exceeding bone sarcomas and leukaemias due to internally deposited strontium and the number of exceeding cancers due to caesium remains in the limits of statistical variations of naturally occurring cancers. (authors)

  18. Support for National Health Insurance Seven Years Into Massachusetts Healthcare Reform: Views of Populations Targeted by the Reform.

    Science.gov (United States)

    Saluja, Sonali; Zallman, Leah; Nardin, Rachel; Bor, David; Woolhandler, Steffie; Himmelstein, David U; McCormick, Danny

    2016-01-01

    Before the Affordable Care Act (ACA), many surveys showed majority support for national health insurance (NHI), also known as single payer; however, little is currently known about views of the ACA's targeted population. Massachusetts residents have had seven years of experience with state health care reform that became the model for the ACA. We surveyed 1,151 adults visiting safety-net emergency departments in Massachusetts in late 2013 on their preference for NHI or the Massachusetts reform and on their experiences with insurance. Most of the patients surveyed were low-income and non-white. The majority of patients (72.0%) preferred NHI to the Massachusetts reform. Support for NHI among those with public insurance, commercial insurance, and no insurance was 68.9%, 70.3%, and 86.3%, respectively (p reform, a reappraisal of the ACA's ability to meet the needs of underserved patients is warranted. © The Author(s) 2015.

  19. Late simultaneous metastasis of renal cell carcinoma to the submandibular and thyroid glands seven years after radical nephrectomy.

    Science.gov (United States)

    Miah, Mohammed S; White, Sharon J; Oommen, George; Birney, Esther; Majumdar, Samit

    2010-01-01

    Background. Renal cell carcinoma (RCC) metastasis to the salivary glands is extremely rare. Most cases reported previously have involved the parotid gland and only six cases involving the submandibular gland exist in the current literature. Metastasis of RCC to thyroid gland is also rare but appears to be more common than to salivary glands. Methods and Results. We present the first case of simultaneous metastasis to the submandibular and thyroid glands from clear cell RCC in a 61-year-old woman who presented seven years after the primary treatment. The submandibular and thyroid glands were excised completely with preservation of the marginal mandibular and recurrent laryngeal nerves, respectively. Conclusion. Metastatic disease should always be considered in the differential diagnosis for patients who present with painless salivary or thyroid gland swelling with a previous history of RCC. If metastatic disease is confined only to these glands, prompt surgical excision can be curative.

  20. Rathke cleft cyst in seven-year-old girl presenting with central diabetes insipidus and review of literature.

    Science.gov (United States)

    Evliyaoglu, Olcay; Evliyaoglu, Cetin; Ayva, Sebnem

    2010-05-01

    Rathke cleft cysts (RCC) are benign cysts derived from remnants of Rathke cleft, and are rarely symptomatic in children. Symptoms due to RCC are associated with mass effect and pituitary hormone deficiencies. Slow growth rate of the cyst makes its incidence increase with aging. Here we report on a seven-year-old girl who presented with central diabetes insipidus (CDI). Her sella MRI revealed a lesion in the sellar region which grew rapidly in follow-up. She underwent microneurosurgical operation and the lesion was totally excised. Pathologic examination revealed RCC with degenerative changes. In her follow-up, growth hormone deficiency developed in addition to arginine vasopressin deficiency. Rapid growth of the cyst is not the usual course of RCC's. Mechanisms regarding the cyst growth are unclear as they are in this case. This is the youngest child to date presenting with central diabetes insipidus due to RCC. Rapid growth of RCC can cause CDI in young children.

  1. Application of Prefabricated Panels for the Energy Retrofit of Portuguese Residential Buildings Facades: A Case Study

    Directory of Open Access Journals (Sweden)

    Sousa J.

    2013-09-01

    Full Text Available This article aims to evaluate the potential application of prefabricated panels in energy retrofit of facades in the Portuguese building stock. The fundamentals of this study were part of Annex 50, which was an international ECBCS IEA project, with the purpose of developing an innovative concept of building renovation for the most representative buildings based on prefabricated systems. To analyze the potential application of energy retrofit using prefabricated panels, was important to know the reality of the existing building stock and its morphology. To know the reality of the building stock, an analysis was done based on the existing statistical data and to find the most representative residential buildings, target of the study, three criteria were defined: buildings built before 1990, with 2 to 6 floors and with renovation needs in the exterior envelope.

  2. Two case studies: QuietRock QR-530 drywall panels in new and remediated multifamily construction

    Science.gov (United States)

    Tinianov, Brian D.

    2005-09-01

    Reliable acoustical isolation continues to be a high risk element of contemporary multifamily construction. Traditional construction techniques, offering potentially high acoustical performance, exist but may be compromised during typical construction or occupation. This paper presents two case studies using a new class of construction material-drywall panels employing constrained layer damping. QuietRock QR-530 damped gypsum board panels are used in a new construction project and as part of a remediation treatment. In a first study, QR-530 panels were used as a drywall alternative in a 2×6, semistaggered, framed wall separating luxury condominiums. Field evaluation per ASTM E36 revealed a normalized noise isolation class of 56. In a second case study, a single layer of QuietRock was applied directly to an existing single stud assembly in a resort hotel. Before and after testing yielded a change of 14 points, raising the noise isolation class from 36 to 50. This paper reviews the details of the test cases and the underlying physical principals of the subject materials.

  3. A numerical study of latent thermal energy storage in a phase change material/carbon panel

    Energy Technology Data Exchange (ETDEWEB)

    Mekaddem, Najoua, E-mail: mekaddem.najoua@gmail.com; Ali, Samia Ben, E-mail: samia.benali@enig.rnu.tn; Hannachi, Ahmed, E-mail: ahmed.hannachi@enig.rnu.tn [Research Laboratory of Process Engineering and Industrial Systems, National Engineering School of Gabes (Tunisia); Mazioud, Atef, E-mail: mazioud@u-pec.fr [IUT Senart, Department of Industrial Engineering and Maintenance, University Paris-Est (France)

    2016-07-25

    To reduce the energetic dependence of building, it has become necessary to explore and develop new materials promoting energy conservation. Because of their high storage capacity, phase change materials (PCMs) are efficient to store thermal energy. In this paper, a 3D model was studied for simulation of energy storing cycles to predict the performances of PCM loaded panels. Carbon was used as supporting material for the PCM. The simulation was based on the enthalpy method using Ansys Fluent software. The panel was exposed to a daily heat flow including the effects of convection and radiation. The results show that the temperature decreased of approximately 2.5°C with a time shift about 2 hours. The steady state was reached after four cycles. Thus, after four cycles the PCM showed its effects on the temperature conditioning.

  4. A numerical study of latent thermal energy storage in a phase change material/carbon panel

    Science.gov (United States)

    Mekaddem, Najoua; Ali, Samia Ben; Mazioud, Atef; Hannachi, Ahmed

    2016-07-01

    To reduce the energetic dependence of building, it has become necessary to explore and develop new materials promoting energy conservation. Because of their high storage capacity, phase change materials (PCMs) are efficient to store thermal energy. In this paper, a 3D model was studied for simulation of energy storing cycles to predict the performances of PCM loaded panels. Carbon was used as supporting material for the PCM. The simulation was based on the enthalpy method using Ansys Fluent software. The panel was exposed to a daily heat flow including the effects of convection and radiation. The results show that the temperature decreased of approximately 2.5°C with a time shift about 2 hours. The steady state was reached after four cycles. Thus, after four cycles the PCM showed its effects on the temperature conditioning.

  5. NANO-BATTERY TECHNOLOGY FOR EV-HEV PANEL: A PIONEERING STUDY

    Directory of Open Access Journals (Sweden)

    Ataur Rahman

    2015-11-01

    Full Text Available Global trends toward CO2 reduction and resource efficiency have significantly increased the importance of lightweight materials for automobile original equipment manufacturers (OEM. CO2 reduction is a fundamental driver for a more lightweight automobile. The introduction of Electrical Vehicles (EVs is one initiative towards this end. However EVs are currently facing several weaknesses: limited driving range, battery pack heaviness, lack of safety and thermal control, high cost, and overall limited efficiency. This study presents a panel-style nano-battery technology built into an EV with CuO filler solid polymer electrolyte (SPE sandwiched by carbon fiber (CF and lithium (Li plate. In addition to this, an aluminum laminated polypropylene film is used as the electromagnetic compatibility (EMC shield. The proposed battery body panel of the EV would reduce the car weight by about 20%, with a charge and discharge capacity of 1.5 kWh (10% of car total power requirement, and provide the heat insulation for the car which would save about 10% power consumption of the air conditioning system. Therefore, the EV would be benefited by 30% in terms of energy reduction by using the proposed body. Furthermore, the proposed body is considered environmental-friendly since it is recyclable for use in a new product. However, the main limiting factors of the SPE are its thermal behavior and moderate ionic conductivity at low temperatures. The SPE temperature is maintained by controlling the battery panel charging/discharge rate. It is expected that the proposed panel-style nano-battery use in an EV would save up to 6.00 kWh in battery energy, equivalent to 2.81 liters of petrol and prevent 3.081 kg of CO2 emission for a travel distance of 100 km. KEYWORDS: epoxy resin; carbon fiber; lithium thin plate; energy generation; solid electrolyte battery

  6. The Tsimane' Amazonian Panel Study (TAPS): Nine years (2002-2010) of annual data available to the public.

    Science.gov (United States)

    Leonard, William R; Reyes-García, Victoria; Tanner, Susan; Rosinger, Asher; Schultz, Alan; Vadez, Vincent; Zhang, Rebecca; Godoy, Ricardo

    2015-12-01

    This brief communication contains a description of the 2002-2010 annual panel collected by the Tsimane' Amazonian Panel Study team. The study took place among the Tsimane', a native Amazonian society of forager-horticulturalists. The team tracked a wide range of socio-economic and anthropometric variables from all residents (633 adults ≥16 years; 820 children) in 13 villages along the Maniqui River, Department of Beni. The panel is ideally suited to examine how market exposure and modernization affect the well-being of a highly autarkic population and to examine human growth in a non-Western rural setting. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Search for Gamma-Ray Emission from AE Aquarii with Seven Years of Fermi-LAT Observations

    Science.gov (United States)

    Li, Jian; Torres, Diego F.; Rea, Nanda; de Oña Wilhelmi, Emma; Papitto, Alessandro; Hou, Xian; Mauche, Christopher W.

    2016-11-01

    AE Aquarii (AE Aqr) is a cataclysmic binary hosting one of the fastest rotating ({P}{spin} = 33.08 s) white dwarfs (WDs) known. Based on seven years of Fermi Large Area Telescope (LAT) Pass 8 data, we report on a deep search for gamma-ray emission from AE Aqr. Using X-ray observations from ASCA, XMM-Newton, Chandra, Swift, Suzaku, and NuSTAR, spanning 20 years, we substantially extend and improve the spin ephemeris of AE Aqr. Using this ephemeris, we searched for gamma-ray pulsations at the spin period of the WD. No gamma-ray pulsations were detected above 3σ significance. Neither phase-averaged gamma-ray emission nor gamma-ray variability of AE Aqr is detected by Fermi LAT. We impose the most restrictive upper limit to the gamma-ray flux from AE Aqr to date: 1.3× {10}-12 erg cm-2 s-1 in the 100 MeV-300 GeV energy range, providing constraints on models.

  8. Failure of uniformly compression loaded debond damaged sandwich panels — An experimental and numerical study

    DEFF Research Database (Denmark)

    Moslemian, Ramin; Quispitupa, Amilcar; Berggreen, Christian

    2012-01-01

    This paper deals with the failure of compression-loaded sandwich panels with an implanted circular face/core debond. Uniform compression tests were conducted on intact sandwich panels with three different types of core material (H130, H250 and PMI) and on similar panels with circular face...

  9. The interaction between environmental norms and behaviour: A panel study of organic food consumption

    DEFF Research Database (Denmark)

    Thøgersen, John; Ølander, Carl Folke

    This paper is based on the conviction that one can get a deeper understanding of the atti-tude-norm-behavior relationship in the environmental field by analyzing the dynamic in-teraction over time between relevant attitudinal variables and specific behaviors of interest. In this paper we present ...... the results of such an analysis, based on a panel survey with a random sample of about 2400 Danes interviewed up to three times in the period 1998 to 2000. The subject matter of the study is the purchase of organic food products....

  10. A panel study of migration, self-selection and household real income.

    Science.gov (United States)

    Axelsson, R; Westerlund, O

    1998-02-01

    "The impact of migration on income for Swedish multi-adult households is examined using panel data pertaining to a sample of stable household constellations during the period 1980-1990. In contrast to previous studies, data on household disposable income is employed in estimating the income function. The empirical results indicate no significant effect on real disposable income from migration. In addition, the hypothesis of no self-selection, or zero correlation between the errors in the decision function and the income function, cannot be rejected." excerpt

  11. Relations between anthropometric and motor variables of seven-year-old girls with the differentiated level of nutritional status

    Directory of Open Access Journals (Sweden)

    Ivanović Miroljub

    2017-01-01

    Full Text Available The objective of this paper is to examine the frequency of nutritional status and the relations between anthropometric characteristics and motor skills of the first-grade elementary schools girls from Valjevo. A battery of 16 anthropometric measurements and 9 motor tests was conducted on the pertinent sample (N = 332 of seven-year-old girls. Data were analyzed using common measures of central tendency, measures of variability and canonical correlation analysis. Based on the measured body mass index, 75% of participants have normal body mass, 21% has increased body mass, and 4% is overweight. The results showed that in the group of participants with normal body mass there is no significant connection between two systems of variables (morphological characteristics and motor skills. Data from the group of overweight participants show that the two statistically relevant correlations were extracted in the morpho-motoric space and were interpreted as canonical functions: (1 circular dimensionality of the skeleton and body mass, and explosive strength and (2 subcutaneous fatty tissue and segmented run and running speed. Canonical factors indicate that the greater the size of chest, thigh, shin and body mass, the lower are the results of the composite motor tests (plyometric jump, forward lean-backward lean-throw, long jump and standing jump, that is the girls who had higher values of back skinfold, stomach skinfold, thigh skinfold and shin skinfold, had worse result realization of motor tasks (hand-tapping, foot-tapping and running 5 x 10 m. Empirical data of the research on the isolated canonical structure are relevant from the theoretical point of view, but they also have relevant implications for identifying increased level of nutritional status and the advancement of physical education in elementary school education.

  12. Studying Impact Damage on Carbon-Fiber Reinforced Aircraft Composite Panels with Sonicir

    Science.gov (United States)

    Han, Xiaoyan; Zhao, Xinyue; Zhang, Ding; He, Qi; Song, Yuyang; Lubowicki, Anthony; Newaz, Golam.; Favro, Lawrence D.; Thomas, Robert L.

    2011-06-01

    Composites are becoming more important materials in commercial aircraft structures such as the fuselage and wings with the new B787 Dreamliner from Boeing which has the target to utilize 50% by weight of composite materials. Carbon-fiber reinforced composites are the material of choice in aircraft structures. This is due to their light weight and high strength (high strength-to-weight ratio), high specific stiffness, tailorability of properties, design flexibility etc. Especially, by reducing the aircraft's body weight by using such lighter structures, the cost of fuel can be greatly reduced with the high jet fuel price for commercial airlines. However, these composites are prone to impact damage and the damage may occur without any observable sign on the surface, yet resulting in delaminations and disbonds that may occur well within the layers. We are studying the impact problem with carbon-fiber reinforced composite panels and developing SonicIR for this application as a fast and wide-area NDE technology. In this paper, we present our results in studying composite structures including carbon-fiber reinforced composite materials, and preliminary quantitative studies on delamination type defect depth identification in the panels.

  13. Studying impact damage on carbon-fiber reinforced aircraft composite panels with sonicir

    International Nuclear Information System (INIS)

    Han Xiaoyan; Zhang Ding; He Qi; Song Yuyang; Lubowicki, Anthony; Zhao Xinyue; Newaz, Golam.; Favro, Lawrence D.; Thomas, Robert L.

    2011-01-01

    Composites are becoming more important materials in commercial aircraft structures such as the fuselage and wings with the new B787 Dreamliner from Boeing which has the target to utilize 50% by weight of composite materials. Carbon-fiber reinforced composites are the material of choice in aircraft structures. This is due to their light weight and high strength (high strength-to-weight ratio), high specific stiffness, tailorability of properties, design flexibility etc. Especially, by reducing the aircraft's body weight by using such lighter structures, the cost of fuel can be greatly reduced with the high jet fuel price for commercial airlines. However, these composites are prone to impact damage and the damage may occur without any observable sign on the surface, yet resulting in delaminations and disbonds that may occur well within the layers. We are studying the impact problem with carbon-fiber reinforced composite panels and developing SonicIR for this application as a fast and wide-area NDE technology. In this paper, we present our results in studying composite structures including carbon-fiber reinforced composite materials, and preliminary quantitative studies on delamination type defect depth identification in the panels.

  14. Evaluation of the analytical performance of a fuel cell breath alcohol testing instrument: a seven-year comprehensive study.

    Science.gov (United States)

    Leonard, Robert J

    2012-11-01

    Between 2003 and 2009, 54,255 breath test sequences were performed on 129 AlcoSensor IV-XL evidential instruments in Orange County, CA. The overall mean breath alcohol concentration and standard deviation from these tests was 0.141 ± 0.051 g/210 L. Of these test sequences, 38,580 successfully resulted in two valid breath alcohol results, with 97.5% of these results agreeing within ±0.020 g/210 L of each other and 86.3% within ±0.010 g/210 L. The mean absolute difference between duplicate tests was 0.006 g/210 L with a median of 0.004 g/210 L. Of the 2.5% of duplicate test results that did not agree within ±0.020 g/210 L, 95% of these had a breath alcohol concentration of 0.10 g/210 L or greater and 77% had an alcohol concentration of 0.15 g/210 L or greater. The data indicate that the AlcoSensor IV-XL can measure a breath sample for alcohol concentration with adequate precision even amid the effects of biological variations. © 2012 American Academy of Forensic Sciences.

  15. Computational and experimental studies of microvascular void features for passive-adaptation of structural panel dynamic properties

    Science.gov (United States)

    Sears, Nicholas C.; Harne, Ryan L.

    2018-01-01

    The performance, integrity, and safety of built-up structural systems are critical to their effective employment in diverse engineering applications. In conflict with these goals, harmonic or random excitations of structural panels may promote large amplitude oscillations that are particularly harmful when excitation energies are concentrated around natural frequencies. This contributes to fatigue concerns, performance degradation, and failure. While studies have considered active or passive damping treatments that adapt material characteristics and configurations for structural control, it remains to be understood how vibration properties of structural panels may be tailored via internal material transitions. Motivated to fill this knowledge gap, this research explores an idea of adapting the static and dynamic material distribution of panels through embedded microvascular channels and strategically placed voids that permit the internal movement of fluids within the panels for structural dynamic control. Finite element model and experimental investigations probe how redistributing material in the form of microscale voids influences the global vibration modes and natural frequencies of structural panels. Through parameter studies, the relationships among void shape, number, size, and location are quantified towards their contribution to the changing structural dynamics. For the panel composition and boundary conditions considered in this report, the findings reveal that transferring material between strategically placed voids may result in eigenfrequency changes as great as 10.0, 5.0, and 7.4% for the first, second, and third modes, respectively.

  16. GAMMA-RAY EMISSION FROM PSR J0007+7303 USING SEVEN YEARS OF FERMI LARGE AREA TELESCOPE OBSERVATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Li, Jian; Torres, Diego F.; De Oña Wilhelmi, Emma; Rea, Nanda; Martin, Jonatan [Institute of Space Sciences (CSIC–IEEC), Campus UAB, Carrer de Magrans s/n, E-08193 Barcelona (Spain)

    2016-11-01

    Based on more than seven years of Fermi Large Area Telescope Pass 8 data, we report on a detailed analysis of the bright gamma-ray pulsar (PSR) J0007+7303. We confirm that PSR J0007+7303 is significantly detected as a point source also during the off-peak phases with a test statistic value of 262 (∼16 σ ). In the description of the off-peak spectrum of PSR J0007+7303, a power law with an exponential cutoff at 2.7 ± 1.2 ± 1.3 GeV (the first/second uncertainties correspond to statistical/systematic errors) is preferred over a single power law at a level of 3.5 σ . The possible existence of a cutoff hints at a magnetospheric origin of the emission. In addition, no extended gamma-ray emission is detected that is compatible with either the supernova remnant (CTA 1) or the very high-energy (>100 GeV) pulsar wind nebula. A flux upper limit of 6.5 × 10{sup −12} erg cm{sup −2} s{sup −1} in the energy range 10–300 GeV is reported, for an extended source assuming the morphology of the VERITAS detection. During on-peak phases, a sub-exponential cutoff is significantly preferred (∼11 σ ) for representing the spectral energy distribution, in both the phase-averaged and phase-resolved spectra. Three glitches are detected during the observation period and we found no flux variability at the time of the glitches or in the long-term behavior. We also report the discovery of a previously unknown gamma-ray source in the vicinity of PSR J0007+7303, Fermi J0020+7328, which we associate with the z = 1.781 quasar S5 0016+73. A concurrent analysis of this source is needed to correctly characterize the behavior of CTA 1 and it is also presented in the paper.

  17. An Empirical Study Of Productivity Growth In EU28 - Spatial Panel Analysis

    Directory of Open Access Journals (Sweden)

    Olejnik Alicja

    2014-12-01

    Full Text Available This paper investigates the spatial process of productivity growth in the European Union on the foundations of the theory of New Economic Geography. The proposed model is based on the study of NUTS 2 regions and takes into consideration a spatial weights matrix in order to better describe the structure of spatial dependence between EU regions. Furthermore, our paper attempts to investigate the applicability of some new approaches to spatial modelling including parameterization of the spatial weights matrix. Our study presents an application of the spatial panel model with fixed effects to Fingleton’s theoretical framework. We suggest that the applied approach constitutes an innovation to spatial econometric studies providing additional information hence, a deeper analysis of the investigated problem.

  18. Reporting studies on time to diagnosis: proposal of a guideline by an international panel (REST).

    Science.gov (United States)

    Launay, Elise; Cohen, Jérémie F; Bossuyt, Patrick M; Buekens, Pierre; Deeks, Jonathan; Dye, Timothy; Feltbower, Richard; Ferrari, Andrea; Kramer, Michael; Leeflang, Mariska; Moher, David; Moons, Karel G; von Elm, Erik; Ravaud, Philippe; Chalumeau, Martin

    2016-09-27

    Studies on time to diagnosis are an increasing field of clinical research that may help to plan corrective actions and identify inequities in access to healthcare. Specific features of time to diagnosis studies, such as how participants were selected and how time to diagnosis was defined and measured, are poorly reported. The present study aims to derive a reporting guideline for studies on time to diagnosis. Each item of a list previously used to evaluate the completeness of reporting of studies on time to diagnosis was independently evaluated by a core panel of international experts (n = 11) for relevance and readability before an open electronic discussion allowed consensus to be reached on a refined list. The list was then submitted with an explanatory document to first, last and/or corresponding authors (n = 98) of published systematic reviews on time to diagnosis (n = 45) for relevance and readability, and finally approved by the core expert panel. The refined reporting guideline consists of a 19-item checklist: six items are about the process of participant selection (with a suggested flowchart), six about the definition and measurement of time to diagnosis, and three about optional analyses of associations between time to diagnosis and participant characteristics and health outcomes. Of 24 responding authors of systematic reviews, more than 21 (≥88 %) rated the items as relevant, and more than 17 (≥70 %) as readable; 19 of 22 (86 %) authors stated that they would potentially use the reporting guideline in the future. We propose a reporting guideline (REST) that could help authors, reviewers, and editors of time to diagnosis study reports to improve the completeness and the accuracy of their reporting.

  19. Particulate matter over a seven year period in urban and rural areas within, proximal and far from mining and power station operations in Greece.

    Science.gov (United States)

    Triantafyllou, A G; Zoras, S; Evagelopoulos, V

    2006-11-01

    Lignite mining operations and lignite-fired power stations result in major particulate pollution (fly ash and fugitive dust) problems in the areas surrounding these activities. The problem is more complicated, especially, for urban areas located not far from these activities, due to additional contribution from the urban pollution sources. Knowledge of the distribution of airborne particulate matter into size fraction has become an increasing area of focus when examining the effects of particulate pollution. On the other hand, airborne particle concentration measurements are useful in order to assess the air pollution levels based on national and international air quality standards. These measurements are also necessary for developing air pollutants control strategies or for evaluating the effectiveness of these strategies, especially, for long periods. In this study an attempt is made in order to investigate the particle size distribution of fly ash and fugitive dust in a heavy industrialized (mining and power stations operations) area with complex terrain in the northwestern part of Greece. Parallel total suspended particulates (TSP) and particulate matter with an aerodynamic diameter less than 10 microm (PM10) concentrations are analyzed. These measurements gathered from thirteen monitoring stations located in the greater area of interest. Spatial, temporal variation and trend are analyzed over the last seven years. Furthermore, the geographical variation of PM10 - TSP correlation and PM10/TSP ratio are investigated and compared to those in the literature. The analysis has indicated that a complex system of sources and meteorological conditions modulate the particulate pollution of the examined area.

  20. Paradoxically high adiponectin in obese 16-year-old girls protects against appearance of the metabolic syndrome and its components seven years later.

    Science.gov (United States)

    Morrison, John A; Glueck, Charles J; Daniels, Stephen; Wang, Ping; Stroop, Davis

    2011-02-01

    To evaluate the relationships of adiponectin levels at age 16 years in obese schoolgirls to metabolic syndrome and its components at age 23 years. Seven-year prospective study of 381 females. In 144 white and 129 black non-obese 16-year old girls (body mass index specific median adiponectin levels (white 12 mg/L, black 11) was used to identify paradoxically high adiponectin levels in obese girls. Of 34 white and 74 black obese girls, 12 (35%) and 19 (26%) had paradoxically high adiponectin levels. In these 108 obese girls, adiponectin levels at age 16 years independently predicted high-density lipoprotein cholesterol (positive) and waist (negative), insulin (negative), and glucose (negative) at age 23 years; paradoxically high adiponectin levels at age 16 years was a negative independent predictor for waist, homeostatic model assessment-insulin resistance, and for the number of abnormal components of the metabolic syndrome at age 23 years. In 31 pairs of obese girls with and without paradoxically high adiponectin levels, matched by race and age 16 body mass index, adiponectin levels at age 16 years was a negative predictor for the number of abnormal metabolic syndrome components at age 23 years. Paradoxically high adiponectin levels in obese 16 year old girls protects against metabolic syndrome and its components at age 23 years. Copyright © 2011 Mosby, Inc. All rights reserved.

  1. Using the Panel Study of Income Dynamics To Analyze Housing Decisions, Dynamics, and Effects.

    Science.gov (United States)

    McGonagle, Katherine; Sastry, Narayan

    The Panel Study of Income Dynamics (PSID) is the world's longest running household panel survey. It started in 1968 and has followed the same families-and their descendants-for nearly 50 years. PSID was conducted annually from 1968 through 1997 and has been conducted biennially since 1997. As of 2015, 39 waves of data have been collected. In 2015, interviews were completed with more than 9,000 households and information was collected on about 25,000 household members. PSID has achieved high wave-to-wave response rates throughout most of its history. Since the beginning of the study, detailed information has been collected on family composition, income, assets and debt, public program participation, and housing. At the beginning of the recent housing crisis, PSID began collecting information about mortgage distress and foreclosure activity. PSID currently includes several major supplemental studies. The Child Development Supplement and the Transition into Adulthood Supplement collect detailed information about behavior and outcomes among children and young adults in PSID families, such as educational achievement, health, time use, family formation, and housing-related decisions among young adults. PSID data are publicly available free of charge to researchers; some data available only under contract to qualified researchers allow linkage with various administrative databases and include information such as census tract and block of residence that can be used to describe neighborhood characteristics. PSID data have been widely used to study topics of major interest to Cityscape readers, including housing decisionmaking, housing expenditures and financing, residential mobility and migration, and the effects of neighborhood characteristics on a variety of measures of child and family well-being. This article provides an overview of PSID and its housing- and neighborhood-related measures. We briefly describe studies using PSID on housing-related topics. Finally, we

  2. Creep Behavior of Structural Insulated Panels (SIPS): Results from a Pilot Study

    Science.gov (United States)

    Dwight McDonald; Marshall Begel; C. Adam Senalik; Robert Ross; Thomas D. Skaggs; Borjen Yeh; Thomas Williamson

    2014-01-01

    Structural insulated panels (SIPs) have been recognized as construction materials in the International Residential Code (IRC) since 2009. Although most SIPs are used in wall applications, they can also be used as roof or floor panels that are subjected to long-term transverse loading, for which SIP creep performance may be critical in design. However, limited...

  3. Panel Conditioning in a Longitudinal Study of Adolescents' Substance Use: Evidence from an Experiment

    Science.gov (United States)

    Torche, Florencia; Warren, John Robert; Halpern-Manners, Andrew; Valenzuela, Eduardo

    2012-01-01

    Panel surveys are widely used in sociology to examine life-course trajectories and to assess causal effects. However, when using panel data researchers usually assume that the act of measuring respondents' attitudes and behaviors has no effect on the attributes being measured or on the accuracy of reports about those attributes. Evidence from…

  4. Financial Development and Output Growth: A Panel Study for Asian Countries

    Directory of Open Access Journals (Sweden)

    Sangjoon Jun

    2012-03-01

    Full Text Available This paper investigates the relationship between financial markets and output growth for a panel of 27 Asian countries over 1960-2009. It utilizes the recently-developed panel cointegration techniques to test and estimate the long-run equilibrium relationship between real GDP and financial development proxies. Real GDP and financial development variables are found to have unit roots and to be cointegrated, based on various panel unit root tests and panel cointegration tests. We find that there is a statistically significant positive bi-directional cointegrating relationship between financial development and output growth by three distinct methods of panel cointegration estimation. Empirical findings suggest that financial market development promotes output growth and in turn output growth stimulates further financial development.

  5. Third-grade retention and reading achievement in Texas: a nine year panel study.

    Science.gov (United States)

    Lorence, Jon

    2014-11-01

    The academic performance of over 38,000 Texas students who failed the state's 1994 reading test was examined through their sophomore year in high school. Propensity score matching resulted in strata with retained and promoted students of comparable observed characteristics. Reading scores were analyzed using a two-level hierarchical linear model. Same grade comparisons show that third graders failing the state-mandated reading test who repeated the grade consistently outperformed in later grades the socially promoted children who also failed the third grade test. Additional analyses indicate that alternative explanations for the findings such as omitted variables, regression to the mean, differential panel attrition and cohort effects are not supported. The results are consistent with findings from other recent studies which suggest that grade retention in third grade may help increase student achievement. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. [Experimental studies of reliability of symbolic information perception from the aviation LCD panel].

    Science.gov (United States)

    Ivanov, A I; Lapa, V V; Davydov, V V; Riabinin, V A; Golosov, S Iu

    2014-01-01

    Results of tachistiscopic experiments on reliability of symbol recognition on LCD panel as a function of screen definition (640 x 480, 800 x 600 and 1024 x 768 pixels), angular size of a picture element (10, 15, 20 and 30 angular min) and luminance contrast (LC) with the background (0.2 to 1.4 standard units) are presented. The obtained quantitative relations indicate significance of the above parameters for recognition reliability. Symbols with the size of 30 angular min and LC of 0.5 were recognizable irrespective of screen definition in the study. Recognition of symbols 20 and 15 angular min of size was much dependent on screen definition and LC of symbols. For symbols of size 10 angular min and LC ≥ 1.0 the recognition probability did not exceed 0.59-0.7.

  7. FAKTOR DETERMINAN MARJIN BUNGA BERSIH BANK PEMBANGUNAN DAERAH DI INDONESIA: SUATU STUDI DATA PANEL

    Directory of Open Access Journals (Sweden)

    Pamuji Gesang Raharjo

    2017-03-01

    Full Text Available This paper analyzed the determinants of net interest margins of the regional development banks (BPD inIndonesia. The empirical specification was focused on the reported net interest rate margin that was assumed tobe a function of two sets variables namely bank internal variable and macro economic factor as the externalvariable. The sample used in this study consisted of eight regional developments banks during the first threemonths of 2008 until the fourth three months of 2012. The results of panel data analysis with fixed effect modelshowed that bank internal factors such as Return on Asset (ROA and asset growth (LNSIZE had a contributionto the hight of net interest margin of the regional development banks (BPD in Indonesia. Furthermore, themarket interest rate as a macroeconomic variable had a positive relationship with the net interest margin of theregional development banks.

  8. Optimization of tilt angle for solar panel: Case study for Madinah, Saudi Arabia

    International Nuclear Information System (INIS)

    Benghanem, M.

    2011-01-01

    This article analyzes the optimal choice of the tilt angle for the solar panel in order to collect the maximum solar irradiation. In this paper, the collector surface is assumed to be facing toward equator. The study is based upon the measured values of daily global and diffuse solar radiation on a horizontal surface. It is shown that the optimal angle of tilt (β opt ) for each month, allows us to collected the maximum solar energy for Madinah site. Annual optimum tilt angle is found to be approximately equal to latitude of the location. It is found that the loss in the amount of collected energy when using the yearly average fixed angle is around 8% compared with the monthly optimum tilt β opt .

  9. A study of feasible smart tariff alternatives for smart grid integrated solar panels in India

    International Nuclear Information System (INIS)

    Thakur, Jagruti; Chakraborty, Basab

    2015-01-01

    With the advent of grid connected solar panels in India, the requirement of a separate mechanism for metering and billing is foreseen. The policy framework for addressing this need is under process in various states of India. In the smart grid pilot project at Puducherry, India, a simple net metering mechanism has been incorporated to evaluate and understand the performance of green energy generation through solar panels. The present paper draws a comparison between net metering and gross metering mechanisms, through the analysis of net meter data collected for three different types of consumers from the pilot project at Puducherry. Different scenarios have been evaluated to infer the impacts of specialized billing mechanisms as well as the payback periods on investment made for solar energy systems and the savings that is reflected in the monthly bills. Feed in tariff renders full credit to the renewable energy customers on their electricity bills for the amount of green power, which is sent back to the main grid. This simple mechanism of a credit system would prove to be the most important energy policy for a nation to encourage sustainable energy generation. Due to wide variations in tariffs, requirements and efficiency of utilities across the different states in India, a policy which can accommodate mechanisms of community net metering and aggregate net metering had become a necessity. The paper signifies the crucial and immediate necessity for a feasible and acceptable energy policy so as to realize the benefits of power from the sun. - Highlights: • Study of net metering data in smart grid pilot project in India. • Scenario analysis for savings in electricity under different cases. • Comparison of net metering and gross metering mechanisms. • Net metering is found to be more beneficial than gross metering. • Suggestions for alternative net metering techniques for developing countries.

  10. Fundamental Movement Skills Development under the Influence of a Gymnastics Program and Everyday Physical Activity in Seven-Year-Old Children.

    Science.gov (United States)

    Culjak, Zoran; Miletic, Durdica; Kalinski, Suncica Delas; Kezic, Ana; Zuvela, Frane

    2014-04-01

    The objectives of this study were: a) to examine the influence of an 18-week basic artistic gymnastics program on fundamental movement skills (FMS) development in seven-year-old children; b) to determine correlations between children's daily activities and successful performance of FMS and basic artistic gymnastics skills. Seventy five first grade primary school children took part in this study. A physical education teacher specialized in artistic gymnastics conducted a gymnastics program for 18 weeks, three times a week. The level of gymnastics skills and FMS were identified at the beginning and at the end of the program. The level of gymnastics skills was evaluated by performance of eight artistic gymnastics skills, while FMS were evaluated by the use of FMS-polygon. Physical activity and inactivity was evaluated by using a proxy-questionnaire "Netherlands Physical Activity Questionnaire˝ (NPAQ). According to the dependent samples t test, significant differences were found in the FMS-polygon and all gymnastics skills before and after the 18-week gymnastics program. Increasing correlations were established over time between gymnastics skills and the FMS-polygon. Unorganized daily activity of children significantly correlated with their mastering of gymnastics skills and FMS. The presented findings confirm: (1) the thesis that basic artistic gymnastics skills and FMS could be developed simultaneously, (2) the theory of positive transfer of similar skills between FMS and artistic gymnastic skills. Mastering basic artistic gymnastics skills will provoke improvement of FMS and finally become a prerequisite for successful introduction of learning more complex gymnastics skills. The obtained results imply that an increase of children's unorganized daily activities can improve the mastering of basic gymnastics skills and simultaneously the development of FMS.

  11. Microbial community diversities and taxa abundances in soils along a seven-year gradient of potato monoculture using high throughput pyrosequencing approach.

    Directory of Open Access Journals (Sweden)

    Xing Liu

    Full Text Available BACKGROUND: Previous studies have focused on linking soil community structure, diversity, or specific taxa to disturbances. Relatively little attention has been directed to crop monoculture soils, particularly potato monoculture. Information about microbial community changes over time between monoculture and non-monoculture treatments is lacking. Furthermore, few studies have examined microbial communities in potato monoculture soils using a high throughput pyrosequencing approach. METHODOLOGY/PRINCIPAL FINDINGS: Soils along a seven-year gradient of potato monoculture were collected and microbial communities were characterized using high throughput pyrosequencing approach. Principal findings are as follows. First, diversity (H(Shannon and richness (S(Chao1 indices of bacterial community, but not of fungal community, were linearly decreased over time and corresponded to a decline of soil sustainability represented by yield decline and disease incidence increase. Second, Fusarium, the only soilborne pathogen-associated fungal genus substantially detected, was linearly increased over time in abundance and was closely associated with yield decline. Third, Fusarium abundance was negatively correlated with soil organic matter (OM and total nitrogen (TN but positively with electrical conductivity (EC. Fourth, Fusarium was correlated in abundances with 6 bacterial taxa over time. CONCLUSIONS: Soil bacterial and fungal communities exhibited differential responses to the potato monoculture. The overall soil bacterial communities were shaped by potato monoculture. Fusarium was the only soilborne pathogen-associated genus associated with disease incidence increase and yield decline. The changes of soil OM, TN and EC were responsible for Fusarium enrichment, in addition to selections by the monoculture crop. Acidobacteria and Nitrospirae were linearly decreased over time in abundance, corresponding to the decrease of OM, suggesting their similar

  12. Malaria in Dielmo, a Senegal village: Is its elimination possible after seven years of implementation of long-lasting insecticide-treated nets?

    Science.gov (United States)

    Wotodjo, Amélé Nyedzie; Doucoure, Souleymane; Gaudart, Jean; Diagne, Nafissatou; Diene Sarr, Fatoumata; Faye, Ngor; Tall, Adama; Raoult, Didier; Sokhna, Cheikh

    2017-01-01

    The malaria burden has decreased significantly in recent years in Africa through the widespread use of artemisinin-based combination therapy (ACT) and long-lasting insecticide-treated nets (LLINs). However, the occurrence of malaria resurgences, the loss of immunity of exposed populations constitute among other factors, serious concerns about the future of malaria elimination efforts. This study investigated the evolution of malaria morbidity in Dielmo (Senegal) before and after the implementation of LLINs. A longitudinal study was carried out in Dielmo over eight years, from July 2007 to July 2015. In July 2008, LLINs were offered to all villagers, and in July 2011 and August 2014 the LLINs were renewed. A survey on LLINs use was done each quarter of the year. Thick smears stained with Giemsa, a rapid diagnostic test (RDT) and quantitative polymerase chain reaction (PCR) methods were performed for all cases of fever to assess malaria clinical attacks. Malaria cases were treated with ACT since June 2006. Malaria morbidity has decreased significantly since the implementation of LLINs in Dielmo, together with ACT. However, malaria resurgences have occurred twice during the seven years of LLINs use. These resurgences occurred the first time during the third year after the introduction of LLINs (aIRR (adjusted incidence-rate ratio) [95%CI] = 5.90 [3.53; 9.88] pmalaria cases by the use of ACT as first-line treatment against malaria in addition to the use of LLINs has significantly reduced malaria in Dielmo and allowed to reach the phase of pre-elimination of the disease. However, the occurrence of malaria resurgences raised serious concerns about malaria elimination, which would require additional tools in this village.

  13. Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis

    Directory of Open Access Journals (Sweden)

    Binwu Sheng

    2017-02-01

    Full Text Available Background: The link between body weight status and spinal diseases has been suggested by a number of cross-sectional and cohort studies with a limited range of patient populations. No population-representative samples have been used to examine the link between obesity and spinal diseases. The present study is based on a nationally representative sample drawn from the Medical Expenditure Panel Survey. Methods: Using the cross-sectional sample of the 2014 Medical Expenditure Panel Study, we built four weighted logistic regression analyses of the associations between body weight status and the following four spinal diseases: low back pain, spondylosis, other cervical disorders and intervertebral disc disorder (IDD. Each respondent’s body weight status was used as the key independent variable with three categories: normal/underweight, overweight, and obese. We controlled for marital status, gender, age, smoking status, household income, health insurance coverage, educational attainment and the use of health services for other major categories of diseases. Results: A total sample of 23,048 respondents was used in our analysis. Overweight and obese respondents, as compared to normal/underweight respondents, were more likely to develop lower back problems (Overweight: logged odds = 0.218, p < 0.01; Obese: logged odds = 0.395, p < 0.001 and IDD (Overweight: logged odds = 0.441, p < 0.05; Obese: logged odds = 0.528, p < 0.001. The associations between bodyweight status and spondylitis were statistically insignificant (Overweight: logged odds = 0.281, p = 0.442; Obese: logged odds = 0.680, p = 0.104. The associations between body weight status and other cervical disorders (Overweight: logged odds = −0.116, p = 0.304; Obese: logged odds = −0.160, p = 0.865 were statistically insignificant. Conclusions: As the first study using a national sample to study bodyweight and spinal diseases, our paper supports the hypothesis that obesity adds to the burden

  14. Does Studying Political Science Affect Civic Attitudes?: A Panel Comparison of Students of Politics, Law, and Mass Communication

    Science.gov (United States)

    Esaiasson, Peter; Persson, Mikael

    2014-01-01

    The article evaluates the civic implications of studying political science. Previous research has argued that learning rational choice models of political behavior could be detrimental to civic outcomes. However, results from our two panel surveys of students at Swedish universities show the opposite: studying political science has positive…

  15. A study on development of virtual panel and virtual collaboration system

    International Nuclear Information System (INIS)

    Yoo, H. J.; Park, S. Y.; Lee, M. S.; Hong, J. H.

    2001-01-01

    The Nuclear I and C group of KEPRI has been peforming research and development on the VRCATS, Virtual Reality based Computer Assisted Training System. For the past two years, we have developed the first VRCATS for Youngkwang 1 nuclear power plant. Currently, we are developing an advanced VRCATS for Uljin 3 nuclear power plant. In this paepr, we will describe virtual panel system and VR based collaborate training system (VRCATS) of the Uljin VRCATS. Since Virtual Panel provides the same environment as the real MCR, trainees can expect the same training effect with Virtual Panel as they do with full scope simulator. i.e., trainees can check key variables and operate the plants and get responses with Virtual Panel. VRCTS provides another realistic training environment for trainees. In VRCATS, for example, operators in a group can work together t handle LOCA (Loss of Coolant Accident) according to emergency operation procedures

  16. The Army Training and Leader Development Panel Officer Study Report to the Army

    National Research Council Canada - National Science Library

    2003-01-01

    .... The Panel contacted approximately l3,5OO soldiers in 61 locations worldwide from all cohorts, components, and major commands using surveys, focus group interviews, personal interviews, and independent research...

  17. Cranberry SSR multiplexing panels for DNA horticultural fingerprinting and genetic studies

    Science.gov (United States)

    Cranberry (Vaccinium macrocarpon) is in need of inexpensive high-throughput DNA fingerprinting methods for genetic research and germplasm purity testing for agricultural purposes. Therefore, we designed and validated 16-multiplexing panels containing 61 evenly distributed simple sequence (SSR) marke...

  18. Tailored Panel Management: A Theory-Based Approach to Building and Maintaining Participant Commitment to a Longitudinal Study

    Science.gov (United States)

    Estrada, Mica; Woodcock, Anna; Schultz, P. Wesley

    2014-01-01

    Many psychological processes unfold over time, necessitating longitudinal research designs. Longitudinal research poses a host of methodological challenges, foremost of which is participant attrition. Building on Dillman’s work, we provide a review of how social influence and relationship research informs retention strategies in longitudinal studies. Objective: We introduce the tailored panel management (TPM) approach, which is designed to establish communal norms that increase commitment to a longitudinal study, and this commitment, in turn, increases response rates and buffers against attrition. Specifically, we discuss practices regarding compensation, communication, consistency, and credibility that increase longer term commitment to panel participation. Research design: Throughout the article, we describe how TPM is being used in a national longitudinal study of undergraduate minority science students. TheScienceStudy is a continuing panel, which has 12 waves of data collected across 6 academic years, with response rates ranging from 70% to 92%. Although more than 90% of participants have either left or graduated from their undergraduate degree program, this highly mobile group of people remains engaged in the study. TheScienceStudy has usable longitudinal data from 96% of the original panel. Conclusion: This article combines social psychological theory, current best practice, and a detailed case study to illustrate the TPM approach to longitudinal data collection. The approach provides guidance for other longitudinal researchers, and advocates for empirical research into longitudinal research methodologies. PMID:24590918

  19. Tailored Panel Management: A Theory-Based Approach to Building and Maintaining Participant Commitment to a Longitudinal Study.

    Science.gov (United States)

    Estrada, Mica; Woodcock, Anna; Schultz, P Wesley

    2014-02-01

    Many psychological processes unfold over time, necessitating longitudinal research designs. Longitudinal research poses a host of methodological challenges, foremost of which is participant attrition. Building on Dillman's work, we provide a review of how social influence and relationship research informs retention strategies in longitudinal studies. Objective: We introduce the tailored panel management (TPM) approach, which is designed to establish communal norms that increase commitment to a longitudinal study, and this commitment, in turn, increases response rates and buffers against attrition. Specifically, we discuss practices regarding compensation, communication, consistency, and credibility that increase longer term commitment to panel participation. Research design: Throughout the article, we describe how TPM is being used in a national longitudinal study of undergraduate minority science students. TheScienceStudy is a continuing panel, which has 12 waves of data collected across 6 academic years, with response rates ranging from 70% to 92%. Although more than 90% of participants have either left or graduated from their undergraduate degree program, this highly mobile group of people remains engaged in the study. TheScienceStudy has usable longitudinal data from 96% of the original panel. Conclusion: This article combines social psychological theory, current best practice, and a detailed case study to illustrate the TPM approach to longitudinal data collection. The approach provides guidance for other longitudinal researchers, and advocates for empirical research into longitudinal research methodologies. © The Author(s) 2014.

  20. Preventable trauma deaths: from panel review to population based-studies

    Directory of Open Access Journals (Sweden)

    Vesconi Sergio

    2006-04-01

    Full Text Available Abstract Preventable trauma deaths are defined as deaths which could be avoided if optimal care has been delivered. Studies on preventable trauma deaths have been accomplished initially with panel reviews of pre-hospital and hospital charts. However, several investigators questioned the reliability and validity of this method because of low reproducibility of implicit judgments when they are made by different experts. Nevertheless, number of studies were published all around the world and ultimately gained some credibility, particularly in regions where comparisons were made before and after trauma system implementation with a resultant fall in mortality. During the last decade of century the method of comparing observed survival with probability of survival calculated from large trauma registries has obtained popularity. Preventable trauma deaths were identified as deaths occurred notwithstanding a high calculated probability of survival. In recent years, preventable trauma deaths studies have been replaced by population-based studies, which use databases representative of overall population, therefore with high epidemiologic value. These databases contain readily available information which carry out the advantage of objectivity and large numbers. Nowadays, population-based researches provide the strongest evidence regarding the effectiveness of trauma systems and trauma centers on patient outcomes.

  1. Experimental and numerical study of heat transfer across insulation wall of a refrigerated integral panel van

    International Nuclear Information System (INIS)

    Glouannec, Patrick; Michel, Benoit; Delamarre, Guillaume; Grohens, Yves

    2014-01-01

    This paper presents an experimental and numerical design study of an insulation wall for refrigerated vans. The thermophysical properties of the insulating multilayer panel, the external environment impact (solar irradiation, temperature, etc.) and durability are taken into account. Different tools are used to characterize the thermal performances of the insulation walls and the thermal properties of the insulation materials are measured. In addition, an experiment at the wall scale is carried out and a 2D FEM model of heat and mass transfer within the wall is formulated. Three configurations are studied with this design approach. Multilayer insulation walls containing reflective multi-foil insulation, aerogel and phase change materials (PCM) are tested. Promising results are obtained with these materials, especially the reduction of peak heat transfer and energy consumption during the daytime period. Furthermore, the major influence of solar irradiation is highlighted as it can increase the peak heat transfer crossing the insulation wall by up to 43%. Nevertheless, we showed that the use of reflective multi-foil insulation and aerogel layers allowed decreasing this impact by 27%. - Highlights: • A design study of an insulation wall for a refrigerated van is carried out. • Experimental and numerical studies of multilayer insulation walls are performed. • The major influence of solar irradiation is highlighted. • New insulation materials (reflective multi-foil, aerogel and PCM) are tested

  2. Impact of a new mandatory reporting law on reporting and identification of child sexual abuse: A seven year time trend analysis.

    Science.gov (United States)

    Mathews, Ben; Lee, Xing Ju; Norman, Rosana E

    2016-06-01

    Child sexual abuse is widespread and difficult to detect. To enhance case identification, many societies have enacted mandatory reporting laws requiring designated professionals, most often police, teachers, doctors and nurses, to report suspected cases to government child welfare agencies. Little research has explored the effects of introducing a reporting law on the number of reports made, and the outcomes of those reports. This study explored the impact of a new legislative mandatory reporting duty for child sexual abuse in the State of Western Australia over seven years. We analyzed data about numbers and outcomes of reports by mandated reporters, for periods before the law (2006-2008) and after the law (2009-2012). Results indicate that the number of reports by mandated reporters of suspected child sexual abuse increased by a factor of 3.7, from an annual mean of 662 in the three year pre-law period to 2448 in the four year post-law period. The increase in the first two post-law years was contextually and statistically significant. Report numbers stabilized in 2010-2012, at one report per 210 children. The number of investigated reports increased threefold, from an annual mean of 451 in the pre-law period to 1363 in the post-law period. Significant decline in the proportion of mandated reports that were investigated in the first two post-law years suggested the new level of reporting and investigative need exceeded what was anticipated. However, a subsequent significant increase restored the pre-law proportion, suggesting systemic adaptive capacity. The number of substantiated investigations doubled, from an annual mean of 160 in the pre-law period to 327 in the post-law period, indicating twice as many sexually abused children were being identified. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. X-Ray Radiographic Study of some Panel Painting Icons from the Beginning of the XX Century

    Directory of Open Access Journals (Sweden)

    Ioan EMANDI

    2011-09-01

    Full Text Available Nondestructive investigation methods with penetrating radiations, such as digital radiography and computed tomography proved to be very useful not only in assessing the cultural heritage, but also but also in any restoration and conservation activity by supplying a multitude of micro-structural details regarding a great diversity of works of art. Consequently, present paper presents two case studies regarding the use of digital radiography in investigating panel icons from the Popa Tatu Church, Bucharest. In both cases it was possible to evidence not only the actual state of conservation of wooden panels but also fragments of the oil picture, allowing a better planning of the future conservation work.

  4. Assessing type I error and power of multistate Markov models for panel data-A simulation study.

    Science.gov (United States)

    Cassarly, Christy; Martin, Renee' H; Chimowitz, Marc; Peña, Edsel A; Ramakrishnan, Viswanathan; Palesch, Yuko Y

    2017-01-01

    Ordinal outcomes collected at multiple follow-up visits are common in clinical trials. Sometimes, one visit is chosen for the primary analysis and the scale is dichotomized amounting to loss of information. Multistate Markov models describe how a process moves between states over time. Here, simulation studies are performed to investigate the type I error and power characteristics of multistate Markov models for panel data with limited non-adjacent state transitions. The results suggest that the multistate Markov models preserve the type I error and adequate power is achieved with modest sample sizes for panel data with limited non-adjacent state transitions.

  5. Air pollution and lung function among susceptible adult subjects: a panel study

    Directory of Open Access Journals (Sweden)

    Marconi Achille

    2006-05-01

    Full Text Available Abstract Background Adverse health effects at relatively low levels of ambient air pollution have consistently been reported in the last years. We conducted a time-series panel study of subjects with chronic obstructive pulmonary disease (COPD, asthma, and ischemic heart disease (IHD to evaluate whether daily levels of air pollutants have a measurable impact on the lung function of adult subjects with pre-existing lung or heart diseases. Methods Twenty-nine patients with COPD, asthma, or IHD underwent repeated lung function tests by supervised spirometry in two one-month surveys. Daily samples of coarse (PM10–2.5 and fine (PM2.5 particulate matter were collected by means of dichotomous samplers, and the dust was gravimetrically analyzed. The particulate content of selected metals (cadmium, chrome, iron, nickel, lead, platinum, vanadium, and zinc was determined by atomic absorption spectrometry. Ambient concentrations of nitrogen dioxide (NO2, carbon monoxide (CO, ozone (O3, and sulphur dioxide (SO2 were obtained from the regional air-quality monitoring network. The relationships between concentrations of air pollutants and lung function parameters were analyzed by generalized estimating equations (GEE for panel data. Results Decrements in lung function indices (FVC and/or FEV1 associated with increasing concentrations of PM2.5, NO2 and some metals (especially zinc and iron were observed in COPD cases. Among the asthmatics, NO2 was associated with a decrease in FEV1. No association between average ambient concentrations of any air pollutant and lung function was observed among IHD cases. Conclusion This study suggests that the short-term negative impact of exposure to air pollutants on respiratory volume and flow is limited to individuals with already impaired respiratory function. The fine fraction of ambient PM seems responsible for the observed effects among COPD cases, with zinc and iron having a potential role via oxidative stress. The

  6. Panel 3

    OpenAIRE

    Lin, Jizhen; Hafren, Lena; Kerschner, Joseph; Li, Jian-Dong; Brown, Steve; Zheng, Qing Y.; Preciado, Diego; Nakamura, Yoshihisa; Huang, Qiuhong; Zhang, Yan

    2017-01-01

    Objective. The objective is to perform a comprehensive review of the literature up to 2015 on the genetics and precision medicine relevant to otitis media. Data Sources. PubMed database of the National Library of Medicine. Review Methods. Two subpanels were formed comprising experts in the genetics and precision medicine of otitis media. Each of the panels reviewed the literature in their respective fields and wrote draft reviews. The reviews were shared with all panel members, and a merged d...

  7. Panel Session

    DEFF Research Database (Denmark)

    Bertelsen, Olav Wedege

    2004-01-01

    In this panel session, four researchers will discuss the role of a theoretical foundation, in particular AT, in the design of information technology based artefacts. The general discussion will take of from a specific examination of the ActAD approach.......In this panel session, four researchers will discuss the role of a theoretical foundation, in particular AT, in the design of information technology based artefacts. The general discussion will take of from a specific examination of the ActAD approach....

  8. Interdisciplinary study of the panel painting depicting the "Pentecostes", attributed to Fernão Gomes

    Directory of Open Access Journals (Sweden)

    Diana Conde

    2010-01-01

    Full Text Available This paper presents a study on the technique and materials used in the panel painting entitled Pentecostes, attributed to the artist Fernão Gomes (XVIIth century, housed in the Museu Nacional de Arte Antiga, in Lisbon. The study also includes the diagnosis of the conservation state of the painting and the description of the cleaning intervention. For identification of the materials and determination of the conservation state, several analytical techniques were used: micro-FTIR and GC-MS, for identification of the binder and varnish; micro-Raman and micro-FTIR, for identification of fillers and pigments; micro-XRF and SEM-EDX, for elemental analysis; optical microscopy, with visible and fluorescent radiation, and infrared photography, for morphological observation and study of pictorial technique. The analytical approach led to the identification of materials common at the time: gypsum with animal glue, lead white, yellow and red ochres, black earths (based on Mn, Bi, Fe, azurite, possible green earth, lead red, oil and oily varnish with residues of cholesterol. After various cleaning tests, a gel suggested by the literature was chosen (recipe no. 105.4 developed by R. Wolbers and proved to be effective in the removal of the aged and polymerized varnish.

  9. Envisioning emerging nanotechnologies: a three-year panel study of South Carolina citizens.

    Science.gov (United States)

    Priest, Susanna; Lane, Thomas; Greenhalgh, Ted; Hand, Lindsey Jo; Kramer, Victoria

    2011-11-01

    This article reports results from a three-year panel study of a nonrandom sample of 76 South Carolina citizens, recruited from a variety of walks of life, and their impressions of emerging nanotechnology. This discussion focuses on material from depth interviews conducted alongside a baseline opinion and awareness inventory at the beginning of the study, the most intensive data-gathering phase. These results are placed in the context of data from three additional surveys conducted at about equal intervals over the three years, plus exit interviews from 21 of the 34 individuals who completed the entire study. The results give insight into popular thinking about technology but little indication of strong emerging concerns, a trajectory of amplification of those concerns, or opinion polarization over time, despite some awareness of risks and potential ethical dimensions. Nanotechnology may stand out more as an example of risk attenuation than of risk amplification, consistent with most results from national surveys. © 2011 Society for Risk Analysis.

  10. Environmental profile analysis of MDF panels production: study in a brazilian technological condition

    Directory of Open Access Journals (Sweden)

    Cassiano Moro Piekarski

    2014-09-01

    Full Text Available The main goal of this study was to analyze the environmental profile of MDF panel manufacturing in the Brazilian industry in terms of energy, emissions and dependence on renewable sources. The study was conducted by using the methodology of Life Cycle Assessment (LCA, specifically through the development of the first Life Cycle Inventory (LCI of MDF in a Brazilian industry. The life cycle inventory and the production processes analysis were constructed using Umberto® v.5.6 software and following the ISO 14040 series. The study covers the life cycle of MDF production from gate-to-gate perspective, involving the on-site manufacturing system. The functional unit was defined in 1 m3 of MDF. About 76% of energy required to produce MDF is thermal (52.8% of thermal energy is required for the drying process of wood fiber. CO2 is a major emission during the MDF production, where natural gas contributes to 96.7% of total CO2 fossils. It was observed a low dependence of non-renewable source (19.2% compared with the literature.

  11. Long-term Evaluation of Cervical Disc Arthroplasty with the Mobi-C© Cervical Disc: A Randomized, Prospective, Multicenter Clinical Trial with Seven-Year Follow-up.

    Science.gov (United States)

    Radcliff, Kris; Davis, Reginald J; Hisey, Michael S; Nunley, Pierce D; Hoffman, Gregory A; Jackson, Robert J; Bae, Hyun W; Albert, Todd; Coric, Dom

    2017-01-01

    Cervical total disc replacement (TDR) is an increasingly accepted procedure for the treatment of symptomatic cervical degenerative disc disease. Multiple Level I evidence clinical trials have established cervical TDR to be a safe and effective procedure in the short-term. The objective of this study is to provide a long-term assessment of TDR versus anterior discectomy and fusion for the treatment of one- and two-level disc disease. This study was a continuation of a prospective, multicenter, randomized, US FDA IDE clinical trial comparing cervical TDR with the Mobi-C © Cervical Disc versus ACDF through 7 years follow-up. Inclusion criteria included a diagnosis of symptomatic cervical degenerative disc disease at one or two cervical levels. TDR patients were treated using a Mobi-C © artificial disc (Zimmer Biomet, Austin TX, USA). ACDF with allograft and anterior plate was used as a control treatment. Outcome measures were collected preoperatively and postoperatively at 6 weeks, at 3, 6, 12, 18 months, annually through 60 months, and at 84 months. Measured outcomes included Overall success, Neck Disability Index (NDI), VAS neck and arm pain, segmental range of motion (ROM), patient satisfaction, SF-12 MCS/PCS, major complications, and subsequent surgery rate. The primary endpoint was an FDA composite definition of success comprising clinical improvement and an absence of major complications and secondary surgery events. A total of 599 patients were enrolled and treated, with 164 treated with one-level TDR, 225 treated with two-level TDR, 81 treated with one-level ACDF, and 105 treated with two-level ACDF. At seven years, follow-up rates ranged from 73.5% to 84.4% (overall 80.2%).The overall success rates of two level TDR and ACDF patients were 60.8% and 34.2%, respectively (p0.05). Both the single and two level TDR and ACDF groups showed significant improvement from baseline NDI scores, VAS neck and arm pain scores, and SF-12 MCS/PCS scores (p<0.0001). In the

  12. Comprehensive embryo testing. Experts' opinions regarding future directions: an expert panel study on comprehensive embryo testing.

    Science.gov (United States)

    Hens, Kristien; Dondorp, Wybo J; Geraedts, Joep P M; de Wert, Guido M

    2013-05-01

    What do scientists in the field of preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS) consider to be the future direction of comprehensive embryo testing? Although there are many biological and technical limitations, as well as uncertainties regarding the meaning of genetic variation, comprehensive embryo testing will impact the IVF/PGD practice and a timely ethical reflection is needed. Comprehensive testing using microarrays is currently being introduced in the context of PGD and PGS, and it is to be expected that whole-genome sequencing will also follow. Current ethical and empirical sociological research on embryo testing focuses on PGD as it is practiced now. However, empirical research and systematic reflection regarding the impact of comprehensive techniques for embryo testing is missing. In order to understand the potential of this technology and to be able to adequately foresee its implications, we held an expert panel with seven pioneers in PGD. We conducted an expert panel in October 2011 with seven PGD pioneers from Belgium, The Netherlands, Germany and the UK. Participants expected the use of comprehensive techniques in the context of PGD. However, the introduction of these techniques in embryo testing requires timely ethical reflection as it involves a shift from choosing an embryo without a particular genetic disease (i.e. PGD) or most likely to result in a successful pregnancy (i.e. PGS) to choosing the best embryo based on a much wider set of criteria. Such ethical reflection should take account of current technical and biological limitations and also of current uncertainties with regard to the meaning of genetic variance. However, ethicists should also not be afraid to look into the future. There was a general agreement that embryo testing will be increasingly preceded by comprehensive preconception screening, thus enabling smart combinations of genetic testing. The group was composed of seven participants from

  13. Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas.

    Directory of Open Access Journals (Sweden)

    Joshua Mark Galanter

    Full Text Available Most individuals throughout the Americas are admixed descendants of Native American, European, and African ancestors. Complex historical factors have resulted in varying proportions of ancestral contributions between individuals within and among ethnic groups. We developed a panel of 446 ancestry informative markers (AIMs optimized to estimate ancestral proportions in individuals and populations throughout Latin America. We used genome-wide data from 953 individuals from diverse African, European, and Native American populations to select AIMs optimized for each of the three main continental populations that form the basis of modern Latin American populations. We selected markers on the basis of locus-specific branch length to be informative, well distributed throughout the genome, capable of being genotyped on widely available commercial platforms, and applicable throughout the Americas by minimizing within-continent heterogeneity. We then validated the panel in samples from four admixed populations by comparing ancestry estimates based on the AIMs panel to estimates based on genome-wide association study (GWAS data. The panel provided balanced discriminatory power among the three ancestral populations and accurate estimates of individual ancestry proportions (R² > 0.9 for ancestral components with significant between-subject variance. Finally, we genotyped samples from 18 populations from Latin America using the AIMs panel and estimated variability in ancestry within and between these populations. This panel and its reference genotype information will be useful resources to explore population history of admixture in Latin America and to correct for the potential effects of population stratification in admixed samples in the region.

  14. Classification of Acute Decompensated Heart Failure (ADHF): An Automated Algorithm Compared to a Physician Reviewer Panel: The ARIC Study

    Science.gov (United States)

    Loehr, Laura R.; Agarwal, Sunil K.; Baggett, Chris; Wruck, Lisa M.; Chang, Patricia P.; Solomon, Scott D.; Shahar, Eyal; Ni, Hanyu; Rosamond, Wayne D.; Heiss, Gerardo

    2013-01-01

    Background An algorithm to classify heart failure (HF) endpoints inclusive of contemporary measures of biomarkers and echocardiography was recently proposed by an international expert panel. Our objective was to assess agreement of HF classification by this contemporaneous algorithm with that by a standardized physician reviewer panel, when applied to data abstracted from community-based hospital records. Methods and Results During 2005-2007, all hospitalizations were identified from four U.S. communities under surveillance as part of the Atherosclerosis Risk in Communities (ARIC) study. Potential HF hospitalizations were sampled by ICD discharge codes and demographics from men and women aged 55 years and older. The HF classification algorithm was automated and applied to 2,729 (N=13,854 weighted hospitalizations) hospitalizations in which either BNP measures or ejection fraction were documented (mean age 75 years). There were 1,403 (54%, N=7,534 weighted) events classified as acute, decompensated HF (ADHF) by the automated algorithm, and 1,748 (68%, N=9,276 weighted) such events by the ARIC reviewer panel. The chance-corrected agreement between ADHF by physician reviewer panel and the automated algorithm was moderate (Kappa=0.39). Sensitivity and specificity of the automated algorithm with ARIC reviewer panel as the referent standard was 0.68 (95% CI, 0.67 - 0.69), and 0.75 (95% CI, 0.74 - 0.76), respectively. Conclusions Although the automated classification improved efficiency and decreased costs, its accuracy in classifying HF hospitalizations was modest compared to a standardized physician reviewer panel. PMID:23650310

  15. When Volunteering Breeds Trust – and When it Does Not A Panel Study of the Volunteering – Trust Relationship

    NARCIS (Netherlands)

    Bekkers, René

    2006-01-01

    It is a common belief that participation in voluntary associations makes citizens more trusting of others. This paper reports longitudinal analyses of volunteering and trust on the Giving in the Netherlands Panel Study (2002-2004; n=1246) refuting this belief. I find that volunteering has little

  16. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

    NARCIS (Netherlands)

    de Vries, Paul S; Sabater-Lleal, Maria; Chasman, Daniel I; Trompet, Stella; Ahluwalia, Tarunveer S; Teumer, Alexander; Kleber, Marcus E; Chen, Ming-Huei; Wang, Jie Jin; Attia, John R; Marioni, Riccardo E; Steri, Maristella; Weng, Lu-Chen; Pool, Rene; Grossmann, Vera; Brody, Jennifer A; Venturini, Cristina; Tanaka, Toshiko; Rose, Lynda M; Oldmeadow, Christopher; Mazur, Johanna; Basu, Saonli; Frånberg, Mattias; Yang, Qiong; Ligthart, Symen; Hottenga, Jouke J; Rumley, Ann; Mulas, Antonella; De Craen, Anton J M; Grotevendt, Anne; Taylor, Kent D; Delgado, Graciela E; Kifley, Annette; Lopez, Lorna M; Berentzen, Tina L; Mangino, Massimo; Bandinelli, Stefania; Morrison, Alanna C; Hamsten, Anders; Tofler, Geoffrey; de Maat, Moniek P M; Draisma, Harmen H M; Lowe, Gordon D; Zoledziewska, Magdalena; Sattar, Naveed; Lackner, Karl J; Völker, Uwe; McKnight, Barbara; Huang, Jie; Holliday, Elizabeth G; McEvoy, Mark A; Starr, John M; Hysi, Pirro G; Hernandez, Dena G; Guan, Weihua; Rivadeneira, Fernando; McArdle, Wendy L; Slagboom, P. Eline; Zeller, Tanja; Psaty, Bruce M; Uitterlinden, André G; de Geus, Eco J C; Stott, David J; Binder, Harald; Hofman, Albert; Franco, Oscar H; Rotter, Jerome I; Ferrucci, Luigi; Spector, Tim D; Deary, Ian J; März, Winfried; Greinacher, Andreas; Wild, Philipp S; Cucca, Francesco; Boomsma, Dorret I; Watkins, Hugh; Tang, Weihong; Ridker, Paul M; Jukema, Jan W; Scott, Rodney J; Mitchell, Paul; Hansen, Torben; O'Donnell, Christopher J; Smith, Nicholas L; Strachan, David P; Dehghan, Abbas

    2017-01-01

    An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associated loci when compared to HapMap imputation. In

  17. The Effects of Respondents' Consent to Be Recorded on Interview Length and Data Quality in a National Panel Study

    Science.gov (United States)

    McGonagle, Katherine A.; Brown, Charles; Schoeni, Robert F.

    2015-01-01

    Recording interviews is a key feature of quality control protocols for most survey organizations. We examine the effects on interview length and data quality of a new protocol adopted by a national panel study. The protocol recorded a randomly chosen one-third of all interviews digitally, although all respondents were asked for permission to…

  18. Modulation of the acute respiratory effects of winter air pollution by serum and dietary antioxidants : a panel study

    NARCIS (Netherlands)

    Grievink, L; Hoek, G; Boezen, HM; van't Veer, P; Brunekreef, B

    This study investigated whether a high dietary intake or serum concentration of antioxidant (pro-) vitamins could attenuate the acute respiratory effects of air pollution in panels of adults (n=227) aged 50-70 yrs with chronic respiratory symptoms in two winters starting in 1993/1994. Subjects

  19. STUDY OF SOME ARCHAEOMETRIC CHARACTERISTICS USED IN PANEL PAINTING ICONS AUTHENTICATION

    Directory of Open Access Journals (Sweden)

    Raluca Anamaria Cristache

    2014-12-01

    Full Text Available The authentication of cultural heritage assets is a complex process of scientific investigation which regards obtaining information about: author (painter, the period when it was made, the owners and other data related to the main contexts of their evolution in time (routes travelled. In fact, the identification of specific archaeometric features is aimed, in determining the materials composition and the patina, then the study of artistic techniques and technology used in the making process of a work of art. Latest serves to define the patrimonial elements and the role of the artifact in time. The expertise of old panel painting icons requires an interdisciplinary approach, correlating the artistic style with technique and materials used. In this regard, the specific techniques of microscopy and spectroscopy are very useful tools for determining the composition of structural elements and their deterioration / degradation state. This work presents a comparative study of the paper used in the preparation layer of three icons painted in Russian style. As an analysis techniques were used the micro and macro photography assisted by Optical Microscopy (OM, SEM-EDX and micro-FTIR. Based on the experimental data obtained, it was found that the icons belong to the first half of the 19th century.

  20. Building Energy Storage Panel Based on Paraffin/Expanded Perlite: Preparation and Thermal Performance Study

    Directory of Open Access Journals (Sweden)

    Xiangfei Kong

    2016-01-01

    Full Text Available This study is focused on the preparation and performance of a building energy storage panel (BESP. The BESP was fabricated through a mold pressing method based on phase change material particle (PCMP, which was prepared in two steps: vacuum absorption and surface film coating. Firstly, phase change material (PCM was incorporated into expanded perlite (EP through a vacuum absorption method to obtain composite PCM; secondly, the composite PCM was immersed into the mixture of colloidal silica and organic acrylate, and then it was taken out and dried naturally. A series of experiments, including differential scanning calorimeter (DSC, scanning electron microscope (SEM, best matching test, and durability test, have been conducted to characterize and analyze the thermophysical property and reliability of PCMP. Additionally, the thermal performance of BESP was studied through a dynamic thermal property test. The results have showed that: (1 the surface film coating procedure can effectively solve the leakage problem of composite phase change material prepared by vacuum impregnation; (2 the optimum adsorption ratio for paraffin and EP was 52.5:47.5 in mass fraction, and the PCMP has good thermal properties, stability, and durability; and (3 in the process of dynamic thermal performance test, BESP have low temperature variation, significant temperature lagging, and large heat storage ability, which indicated the potential of BESP in the application of building energy efficiency.

  1. Building Energy Storage Panel Based on Paraffin/Expanded Perlite: Preparation and Thermal Performance Study.

    Science.gov (United States)

    Kong, Xiangfei; Zhong, Yuliang; Rong, Xian; Min, Chunhua; Qi, Chengying

    2016-01-25

    This study is focused on the preparation and performance of a building energy storage panel (BESP). The BESP was fabricated through a mold pressing method based on phase change material particle (PCMP), which was prepared in two steps: vacuum absorption and surface film coating. Firstly, phase change material (PCM) was incorporated into expanded perlite (EP) through a vacuum absorption method to obtain composite PCM; secondly, the composite PCM was immersed into the mixture of colloidal silica and organic acrylate, and then it was taken out and dried naturally. A series of experiments, including differential scanning calorimeter (DSC), scanning electron microscope (SEM), best matching test, and durability test, have been conducted to characterize and analyze the thermophysical property and reliability of PCMP. Additionally, the thermal performance of BESP was studied through a dynamic thermal property test. The results have showed that: (1) the surface film coating procedure can effectively solve the leakage problem of composite phase change material prepared by vacuum impregnation; (2) the optimum adsorption ratio for paraffin and EP was 52.5:47.5 in mass fraction, and the PCMP has good thermal properties, stability, and durability; and (3) in the process of dynamic thermal performance test, BESP have low temperature variation, significant temperature lagging, and large heat storage ability, which indicated the potential of BESP in the application of building energy efficiency.

  2. Numerical modeling for longwall pillar design: a case study from a typical longwall panel in China

    Science.gov (United States)

    Zhang, Guangchao; Liang, Saijiang; Tan, Yunliang; Xie, Fuxing; Chen, Shaojie; Jia, Hongguo

    2018-02-01

    This paper presents a new numerical modeling procedure and design principle for longwall pillar design with the assistance of numerical simulation of FLAC3D. A coal mine located in Yanzhou city, Shandong Province, China, was selected for this case study. A meticulously validated numerical model was developed to investigate the stress changes across the longwall pillar with various sizes. In order to improve the reliability of the numerical modeling, a calibration procedure is undertaken to match the Salamon and Munro pillar strength formula for the coal pillar, while a similar calibration procedure is used to estimate the stress-strain response of a gob. The model results demonstrated that when the coal pillar width was 7-8 m, most of the vertical load was carried by the panel rib, whilst the gateroad was overall in a relatively low stress environment and could keep its stability with proper supports. Thus, the rational longwall pillar width was set as 8 m and the field monitoring results confirmed the feasibility of this pillar size. The proposed numerical simulation procedure and design principle presented in this study could be a viable alternative approach for longwall pillar design for other similar projects.

  3. Unemployment, immigration, and NAFTA: a panel study of ten major U.S. industries.

    Science.gov (United States)

    Amuedo Dorantes, C; Huang W-c

    1997-01-01

    The potential employment effects of the North American Free Trade Agreement (NAFTA) was the central concern of debate before the treaty was eventually passed. Panel data on unemployment rates in 10 major industries in the US during 1983-1994 were analyzed to assess the sensitivity of unemployment rates with respect to industry characteristics, macroeconomic variables, and Canadian and Mexican immigration to the US in the aftermath of the advent of NAFTA. The industries studied are mining; construction, durable goods, nondurable goods, transportation and public utilities; wholesale and retail trade; finance, insurance, and real estate; services; agriculture; and government. Analysis of the data determined that the output produced by the industry, unemployment insurance coverage, and interest rates are significant determinants of industry unemployment rates, but union presence does not affect industry unemployment. Both Canadian and Mexican immigrants seem to complement the US labor force, with Canadian immigrants being highly complementary to US labor. The Chow test found no evidence that NAFTA has changed the structure of unemployment determination in the industries studied.

  4. Clinical investigation of flat panel CT following middle ear reconstruction: a study of 107 patients

    Energy Technology Data Exchange (ETDEWEB)

    Zaoui, K. [University Hospital Heidelberg, Ruprecht Karls University, Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg (Germany); Kromeier, J. [St. Josefs Hospital, RkK, Department of Radiology, Freiburg (Germany); Neudert, M.; Beleites, T.; Zahnert, T. [University Hospital Dresden, Technical University, Department of Otorhinolaryngology, Head and Neck Surgery, Dresden (Germany); Laszig, R.; Offergeld, C. [University Hospital Freiburg, Albert Ludwigs University, Department of Otorhinolaryngology, Head and Neck Surgery, Freiburg (Germany)

    2014-03-15

    After middle ear reconstruction using partial or total ossicular replacement prostheses (PORP/TORP), an air-bone gap (ABG) may persist because of prosthesis displacement or malposition. So far, CT of the temporal bone has played the main role in the diagnosis of reasons for postoperative insufficient ABG improvement. Recent experimental and clinical studies have evaluated flat panel CT (fpCT) as an alternative imaging technique that provides images with high isovolumetric resolution, fewer metal-induced artefacts and lower irradiation doses. One hundred and seven consecutive patients with chronic otitis media with or without cholesteatoma underwent reconstruction by PORP (n = 52) or TORP (n = 55). All subjects underwent preoperative and postoperative audiometric testing and postoperative fpCT. Statistical evaluation of all 107 patients as well as the sole sub-assembly groups (PORP or TORP) showed a highly significant correlation between hearing improvement and fpCT-determined prosthesis position. FpCT enables detailed postoperative information on patients with middle ear reconstruction. FpCT is a new imaging technique that provides immediate feedback on surgical results after reconstructive middle ear surgery. Specific parameters evaluated by fpCT may serve as a predictive tool for estimated postoperative hearing improvement. Therefore this imaging technique is suitable for postoperative quality control in reconstructive middle ear surgery. (orig.)

  5. Study on steel plate reinforced concrete panels subjected to cyclic in-plane shear

    International Nuclear Information System (INIS)

    Ozaki, Masahiko; Akita, Shodo; Osuga, Hiroshi; Nakayama, Tatsuo; Adachi, Naoyuki

    2004-01-01

    This paper describes the derivation of the equation for evaluating the strength of steel plate reinforced concrete structure (SC) and the experimental results of SC panels subjected to in-plane shear. Two experimental research programs were carried out. One was the experimental study in which the influence of the axial force and the partitioning web were investigated, another was that in which the influence of the opening was investigated. In the former program, nine specimens were loaded in cyclic in-plane shear. The test parameters were the thickness of the surface steel plate, the effects of the partitioning web and the axial force. The experimental results were compared with the calculated results, and good agreement between the calculated results and the experimental results was shown. In the later programs, six specimens having an opening were loaded in cyclic in-plane shear, and were compared with the results of the specimen without opening. FEM analysis was used to supplement experimental data. Finally, we proposed the equation to calculate the reduction ratio from the opening for design

  6. Clinical investigation of flat panel CT following middle ear reconstruction: a study of 107 patients

    International Nuclear Information System (INIS)

    Zaoui, K.; Kromeier, J.; Neudert, M.; Beleites, T.; Zahnert, T.; Laszig, R.; Offergeld, C.

    2014-01-01

    After middle ear reconstruction using partial or total ossicular replacement prostheses (PORP/TORP), an air-bone gap (ABG) may persist because of prosthesis displacement or malposition. So far, CT of the temporal bone has played the main role in the diagnosis of reasons for postoperative insufficient ABG improvement. Recent experimental and clinical studies have evaluated flat panel CT (fpCT) as an alternative imaging technique that provides images with high isovolumetric resolution, fewer metal-induced artefacts and lower irradiation doses. One hundred and seven consecutive patients with chronic otitis media with or without cholesteatoma underwent reconstruction by PORP (n = 52) or TORP (n = 55). All subjects underwent preoperative and postoperative audiometric testing and postoperative fpCT. Statistical evaluation of all 107 patients as well as the sole sub-assembly groups (PORP or TORP) showed a highly significant correlation between hearing improvement and fpCT-determined prosthesis position. FpCT enables detailed postoperative information on patients with middle ear reconstruction. FpCT is a new imaging technique that provides immediate feedback on surgical results after reconstructive middle ear surgery. Specific parameters evaluated by fpCT may serve as a predictive tool for estimated postoperative hearing improvement. Therefore this imaging technique is suitable for postoperative quality control in reconstructive middle ear surgery. (orig.)

  7. Experimental Study of the Compression Response of Fluted-Core Composite Panels with Joints

    Science.gov (United States)

    Schultz, Marc R.; Rose, Cheryl A.; Guzman, J. Carlos; McCarville, Douglas; Hilburger, Mark W.

    2012-01-01

    Fluted-core sandwich composites consist of integral angled web members spaced between laminate face sheets, and may have the potential to provide benefits over traditional sandwich composites for certain aerospace applications. However, fabrication of large autoclave-cured fluted-core cylindrical shells with existing autoclaves will require that the shells be fabricated in segments, and joined longitudinally to form a complete barrel. Two different longitudinal fluted-core joint designs were considered experimentally in this study. In particular, jointed fluted-core-composite panels were tested in longitudinal compression because longitudinal compression is the primary loading condition in dry launch-vehicle barrel sections. One of the joint designs performed well in comparison with unjointed test articles, and the other joint design failed at loads approximately 14% lower than unjointed test articles. The compression-after-impact (CAI) performance of jointed fluted-core composites was also investigated by testing test articles that had been subjected to 6 ft-lb impacts. It was found that such impacts reduced the load-carrying capability by 9% to 40%. This reduction is dependent on the joint concept, component flute size, and facesheet thickness.

  8. Experimental Study for Structural Behaviour of Precast Lightweight Panel (PLP) Under Flexural Load

    Science.gov (United States)

    Goh, W. I.; Mohamad, N.; Tay, Y. L.; Rahim, N. H. A.; Jhatial, A. A.; Samad, A. A. A.; Abdullah, R.

    2017-06-01

    Precast lightweight concrete slab is first fabricated in workshop or industrial before construction and then transported to site and installed by skilled labour. It can reduce construction time by minimizing user delay and time for cast-in-situ to increase workability and efficiency. is environmental friendly and helps in resource reduction. Although the foamed concrete has low compressive strength compared to normal weight concrete but it has excellent thermal insulation and sound absorption. It is environmental friendly and helps in resource reduction. To determine the material properties of foamed concrete, nine cubes and six cylindrical specimens were fabricated and the results were recorded. In this study, structural behaviour of precast lightweight panel (PLP) with dry density of 1800 kg/m3 was tested under flexural load. The results were recorded and analysed in terms of ultimate load, crack pattern, load-deflection profiles and strain distribution. Linear Voltage Displacement Transducers (LVDT) and strain gauges were used to determine the deflection and strain distribution of PLP. The theoretical and experimental ultimate load of PLP was analysed and recorded to be 70 and 62 kN respectively, having a difference of 12.9%. Based on the results, it can be observed that PLP can resist the adequate loading. Thus, it can be used in precast industry for construction purposes.

  9. Does financial development reduce environmental degradation? Evidence from a panel study of 129 countries.

    Science.gov (United States)

    Al-Mulali, Usama; Tang, Chor Foon; Ozturk, Ilhan

    2015-10-01

    The purpose of this study is to explore the effect of financial development on CO2 emission in 129 countries classified by the income level. A panel CO2 emission model using urbanisation, GDP growth, trade openness, petroleum consumption and financial development variables that are major determinants of CO2 emission was constructed for the 1980-2011 period. The results revealed that the variables are cointegrated based on the Pedroni cointegration test. The dynamic ordinary least squares (OLS) and the Granger causality test results also show that financial development can improve environmental quality in the short run and long run due to its negative effect on CO2 emission. The rest of the determinants, especially petroleum consumption, are determined to be the major source of environmental damage in most of the income group countries. Based on the results obtained, the investigated countries should provide banking loans to projects and investments that can promote energy savings, energy efficiency and renewable energy to help these countries reduce environmental damage in both the short and long run.

  10. Public policy influence on renewable energy investments—A panel data study across OECD countries

    International Nuclear Information System (INIS)

    Polzin, Friedemann; Migendt, Michael; Täube, Florian A.; Flotow, Paschen von

    2015-01-01

    This paper examines the impact of public policy measures on renewable energy (RE) investments in electricity-generating capacity made by institutional investors. Using a novel combination of datasets and a longitudinal research design, we investigate the influence of different policy measures in a sample of OECD countries to suggest an effective policy mix which could tackle failures in the market for clean energy. The results call for technology-specific policies which take into account actual market conditions and technology maturity. To improve the conditions for institutional investments, advisable policy instruments include economic and fiscal incentives such as feed-in tariffs (FIT), especially for less mature technologies. Additionally, market-based instruments such as greenhouse gas (GHG) emission trading systems for mature technologies should be included. These policy measures directly impact the risk and return structure of RE projects. Supplementing these with regulatory measures such as codes and standards (e.g. RPS) and long-term strategic planning could further strengthen the context for RE investments. - Highlights: • Panel data study on the effectiveness of policies to induce RE investments. • Novel combination of datasets (BNEF/IEA) in solar, wind and biomass sectors. • FIT proves to be more effective than subsidies for less mature technologies. • RPS and tradable permit systems seem more effective for mature technologies. • A long-term strategic planning framework is useful to attract institutional investors

  11. Panel studies of air pollution on children's lung function and respiratory symptoms: a literature review.

    Science.gov (United States)

    Li, Shanshan; Williams, Gail; Jalaludin, Bin; Baker, Peter

    2012-11-01

    This article reviews panel studies of air pollution on children's respiratory health and proposes future research directions. The PubMed electronic database was used to search published original epidemiological studies in peer-reviewed journals from 2000 to November 2011. Children's age was limited to ≤18 years old. A total of 33 relevant articles were obtained, with 20 articles relating to lung function, 21 articles relating to respiratory symptoms, and 8 articles examining both. Most studies suggested the adverse effects of air pollution on children's lung function and respiratory symptoms. Particles and NO(2) showed more significant results, whereas effects of SO(2) were not consistent. A few studies indicated that O(3) interacted with temperature and sometimes seemed to be a protective factor for children's respiratory health. Negative associations between air pollutants and pulmonary health were more serious in asthmatic children than in healthy subjects. However, many outcomes depended on the number of lag days. Peak expiratory flow (PEF) was the most usual measurement for children's lung function, followed by forced expiratory volume in 1 second (FEV(1)). There are significant adverse effects of air pollution on children's pulmonary health, especially for asthmatics. Future studies need to examine the lag effects of air pollution on children's lung function and respiratory symptoms. Ambient temperature is predicted to change worldwide due to climate change, which will threaten population health. Further research is needed to examine the effects of ambient temperature and the interactive effects between air pollution and ambient temperature on children's lung function and respiratory symptoms.

  12. Panel Unit Root Tests by Combining Dependent Values: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Xuguang Sheng

    2011-01-01

    Full Text Available We conduct a systematic comparison of the performance of four commonly used value combination methods applied to panel unit root tests: the original Fisher test, the modified inverse normal method, Simes test, and the modified truncated product method (TPM. Our simulation results show that under cross-section dependence the original Fisher test is severely oversized, but the other three tests exhibit good size properties. Simes test is powerful when the total evidence against the joint null hypothesis is concentrated in one or very few of the tests being combined, but the modified inverse normal method and the modified TPM have good performance when evidence against the joint null is spread among more than a small fraction of the panel units. These differences are further illustrated through one empirical example on testing purchasing power parity using a panel of OECD quarterly real exchange rates.

  13. Study on the optimum tilted angle of solar panels in Hainan tropical photovoltaic facility agricultural system

    Science.gov (United States)

    Wang, Jingxuan; Ge, Zhiwu; Yang, Xiaoyan; Ye, Chunhua; Lin, Yanxia

    2017-04-01

    Photovoltaic facility agriculture system can effectively alleviate the contradiction between limited land and Photovoltaic power generation. It’s flexible to create suitable environment for crop growth, and generate electricity over the same land at the same time. It’s necessary to set appropriate solar panel angle to get more solar energy. Through detailed analysis and comparison, we chose the Hay’s model as solar radiation model. Based on the official meteorological data got from Haikou Meteorological Bureau, and by comparing the amount of radiation obtained at different tilted angles per month, the optimal placement angle of PV panels at different seasons in Haikou was obtained through calculation, and the optimal placement angle from April to October was also obtained. Through optimized angle and arrangement of solar photovoltaic panels, we can get greater power efficiency.

  14. Vacuum Insulation Panels - Study on VIP-components and panels for service life prediction of VIP in building applications (Subtask A)

    Energy Technology Data Exchange (ETDEWEB)

    Simmler, H.; Brunner, S. [Swiss Federal Laboratories for Materials Testing and Research (EMPA), Duebendorf (Switzerland); Heinemann, U.; Schwab, H. [Bavarian Centre for Applied Energy Research (ZAE Bayern), Garching (Germany); Kumaran, K.; Mukhopadhyaya, P. [National Research Council, Institute for Research in Construction (NRC-IRC), Ottawa (Canada); Quenard, D.; Sallee, H. [Scientific and Technical Centre for Construction (CSTB), Marne la Vallee (France); Noller, K.; Kuecuekpinar-Niarchos, E.; Stramm, C. [Fraunhofer Institute for Process Engineering and Packaging (IVV), Freising (Germany); Tenpierik, M.; Cauberg, H. [Technical University of Delft, Delft (Netherlands); Erb, M. [Dr. Eicher und Pauli AG (Switzerland)

    2005-09-15

    This comprehensive paper takes a look at the properties of vacuum insulation panels (VIP) and was presented as a contribution to the IEA's ECBCS (Energy Conservation in Buildings and Community Systems) Annex 39. The various institutions in Switzerland, Germany, Canada, France, Sweden and the Netherlands participating in the task and their activities are listed. The paper describes the concept of vacuum insulation for buildings and examines the physics involved and core materials that can be used. The physical, mechanical and thermal properties of the core materials are examined and the requirements placed on the envelope of the panels are looked at. Tests made on materials as well as on the complete vacuum insulation panels are described in detail. The results obtained are presented and reviewed. Service-life and quality assurance aspects are also discussed. A comprehensive appendix completes the report.

  15. Measurement of inflammation and oxidative stress following drastic changes in air pollution during the Beijing Olympics: a panel study approach

    Science.gov (United States)

    Kipen, Howard; Rich, David; Huang, Wei; Zhu, Tong; Wang, Guangfa; Hu, Min; Lu, Shou-en; Ohman-Strickland, Pamela; Zhu, Ping; Wang, Yuedan; Zhang, Jim (Junfeng)

    2014-01-01

    Ambient air pollution has been linked to cardiovascular and respiratory morbidity and mortality in epidemiology studies. Frequently, oxidative and nitrosative stress are hypothesized to mediate these pollution effects, however precise mechanisms remain unclear. This paper describes the methodology for a major panel study to examine air pollution effects on these and other mechanistic pathways. The study took place during the drastic air pollution changes accompanying the 2008 Olympics in Beijing, China. After a general description of air pollution health effects, we provide a discussion of panel studies and describe the unique features of this study that make it likely to provide compelling results. This study should lead to a clearer and more precise definition of the role of oxidative and nitrosative stress, as well as other mechanisms, in determining acute morbidity and mortality from air pollution exposure. PMID:20716299

  16. Determinants of personal exposure to ozone in school children. Results from a panel study in Greece.

    Science.gov (United States)

    Dimakopoulou, Konstantina; Grivas, Georgios; Samoli, Evangelia; Rodopoulou, Sophia; Spyratos, Dionisis; Papakosta, Despoina; Karakatsani, Anna; Chaloulakou, Archontoula; Katsouyanni, Klea

    2017-04-01

    In the wider framework of the RESPOZE (ReSPiratory effects of OZone Exposure in Greek children) panel study, we investigated possible determinants of O 3 exposure of school children, measured with personal passive samplers, in Athens and Thessaloniki, Greece. Personal exposure to O 3 was measured for five weeks spread along the academic year 2013-14, in 186 school children in Athens and Thessaloniki, Greece. At the same time, at-school outdoor measurements were performed and ambient levels of 8-h daily maximum O 3 from fixed sites were collected. We also collected information on lifestyle and housing characteristics through an extended general questionnaire (GQ) and each participant completed daily time activity diaries (TADs) during the study period. Mean outdoor concentrations were higher during the warmer months, in the suburbs of the cities and in Athens. Personal exposure concentrations were significantly lower compared to outdoor. Daily levels of at-school outdoor and ambient levels of O 3 from fixed sites were significant determinants of personal exposure to O 3 . For a 10μg/m 3 increase in at-school outdoor O 3 concentrations and PM 10 measurements a 20.9% (95% CI: 13%, 28%) increase in personal exposure to O 3 was found. For a half an hour more spent in transportation an average increase of 7% (95% CI: 0.3%, 14.6%) in personal exposure to O 3 was observed. Among other possible determinants, time spent in transportation (TAD variable) and duration of open windows were the ones associated with personal O 3 exposure levels. Our results support the use of outdoor and ambient measurements from fixed sites in epidemiological studies as a proxy of personal exposure to O 3 , but this has to be calibrated taking into account personal measurements and time-activity patterns. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Effectiveness and Cost-Effectiveness of a Cluster-Randomized Prenatal Lifestyle Counseling Trial: A Seven-Year Follow-Up.

    Directory of Open Access Journals (Sweden)

    Päivi Kolu

    Full Text Available There is a link between the pregnancy and its long-term influence on health and susceptibility to future chronic disease both in mother and offspring. The objective was to determine whether individual counseling on physical activity and diet and weight gain at five antenatal visits can prevent type 2 diabetes mellitus (T2DM and overweight or improve glycemic parameters, among all at-risk-mothers and their children. Another objective was to evaluate whether gestational lifestyle intervention was cost-effective as measured with mother's sickness absence and quality-adjusted life years (QALY. This study was a seven-year follow-up study for women, who were enrolled to the antenatal cluster-randomized controlled trial (RCT. Analysis of the outcome included all women whose outcome was available, in addition with subgroup analysis including women adherent to all lifestyle aims. A total of 173 women with their children participated to the study, representing 43% (173/399 of the women who finished the original RCT. Main outcome measures were: T2DM based on medication use or fasting blood glucose or oral glucose tolerance test (OGTT, body mass index (BMI, glycosylated hemoglobin (HbA1c. None of the women were diagnosed to have T2DM. HbA1c or fasting blood glucose differences were not found among mothers or children. Differences in BMI were non-significant among mothers (Intervention 27.3, Usual care 28.1 kg/m2, p = 0.33 and children (I 21.3 vs U 22.5 kg/m2, p = 0.07. Children's BMI was significantly lower among adherent group (I 20.5 vs U 22.5, p = 0.04. The mean total cost per person was 30.6% lower in the intervention group than in the usual care group (I €2,944 vs. U €4,243; p = 0.74. Intervention was cost-effective in terms of sickness absence but not in QALY gained i.e. if society is willing to pay additional €100 per one avoided sickness absence day; there is a 90% probability of the intervention arm to be cost-effective. Long

  18. A pilot study to evaluate the application of a generic protein standard panel for quality control of biomarker detection technologies

    Directory of Open Access Journals (Sweden)

    Valdivia Hernan J

    2011-08-01

    Full Text Available Abstract Background Protein biomarker studies are currently hampered by a lack of measurement standards to demonstrate quality, reliability and comparability across multiple assay platforms. This is especially pertinent for immunoassays where multiple formats for detecting target analytes are commonly used. Findings In this pilot study a generic panel of six non-human protein standards (50 - 10^7 pg/mL of varying abundance was prepared as a quality control (QC material. Simulated "normal" and "diseased" panels of proteins were prepared in pooled human plasma and incorporated into immunoassays using the Meso Scale Discovery® (MSD® platform to illustrate reliable detection of the component proteins. The protein panel was also evaluated as a spike-in material for a model immunoassay involving detection of ovarian cancer biomarkers within individual human plasma samples. Our selected platform could discriminate between two panels of the proteins exhibiting small differences in abundance. Across distinct experiments, all component proteins exhibited reproducible signal outputs in pooled human plasma. When individual donor samples were used, half the proteins produced signals independent of matrix effects. These proteins may serve as a generic indicator of platform reliability. Each of the remaining proteins exhibit differential signals across the distinct samples, indicative of sample matrix effects, with the three proteins following the same trend. This subset of proteins may be useful for characterising the degree of matrix effects associated with the sample which may impact on the reliability of quantifying target diagnostic biomarkers. Conclusions We have demonstrated the potential utility of this panel of standards to act as a generic QC tool for evaluating the reproducibility of the platform for protein biomarker detection independent of serum matrix effects.

  19. Effects of Asian dust on daily cough occurrence in patients with chronic cough: A panel study

    Science.gov (United States)

    Higashi, Tomomi; Kambayashi, Yasuhiro; Ohkura, Noriyuki; Fujimura, Masaki; Nakai, Satoshi; Honda, Yasushi; Saijoh, Kiyofumi; Hayakawa, Kazuichi; Kobayashi, Fumihisa; Michigami, Yoshimasa; Olando, Anyenda Enoch; Hitomi, Yoshiaki; Nakamura, Hiroyuki

    2014-08-01

    Asian dust, known as kosa in Japanese, is a major public health concern. In this panel study, we evaluated the effects of exposure to kosa on daily cough occurrence. The study subjects were 86 patients being treated for asthma, cough variant asthma, or atopic cough in Kanazawa University Hospital from January 2011 to June 2011. Daily mean concentrations of kosa and spherical particles were obtained from light detection and ranging (LIDAR) measurements, and were categorized from Grade 1 (0 μg/m3) to 5 (over 100 μg/m3). The association between kosa and cough was analyzed by logistic regression with a generalized estimating equation. Kosa effects on cough were seen for all Grades with potential time lag effect. Particularly at Lag 0 (the day of exposure), a dose-response relationship was observed: the odds ratios for Grades 2, 3, 4, and 5 above the referent (Grade 1) were 1.111 (95% confidence interval (CI): 0.995-1.239), 1.171 (95% CI: 1.006-1.363), 1.357 (95% CI: 1.029-1.788), and 1.414 (95% CI: 0.983-2.036), respectively. Among the patients without asthma, the association was higher: the odds ratios for Grades 2, 3, 4 and 5 were 1.223 (95% CI: 0.999-1.497), 1.309 (95% CI: 0.987-1.737), 1.738 (95% CI: 1.029-2.935) and 2.403 (95% CI: 1.158-4.985), respectively. These associations remained after adjusting for the concentration of spherical particles or particulate matter with an aerodynamic diameter of less than 2.5 μm (PM2.5). Our findings demonstrate that kosa is an environmental factor which induces cough in a dose-response relationship.

  20. Evaluation of a seven-year air quality simulation using the Weather Research and Forecasting (WRF)/Community Multiscale Air Quality (CMAQ) models in the eastern United States.

    Science.gov (United States)

    Zhang, Hongliang; Chen, Gang; Hu, Jianlin; Chen, Shu-Hua; Wiedinmyer, Christine; Kleeman, Michael; Ying, Qi

    2014-03-01

    The performance of the Weather Research and Forecasting (WRF)/Community Multi-scale Air Quality (CMAQ) system in the eastern United States is analyzed based on results from a seven-year modeling study with a 4-km spatial resolution. For 2-m temperature, the monthly averaged mean bias (MB) and gross error (GE) values are generally within the recommended performance criteria, although temperature is over-predicted with MB values up to 2K. Water vapor at 2-m is well-predicted but significant biases (>2 g kg(-1)) were observed in wintertime. Predictions for wind speed are satisfactory but biased towards over-prediction with 0study to better understand this

  1. Malaria in Dielmo, a Senegal village: Is its elimination possible after seven years of implementation of long-lasting insecticide-treated nets?

    Directory of Open Access Journals (Sweden)

    Amélé Nyedzie Wotodjo

    Full Text Available The malaria burden has decreased significantly in recent years in Africa through the widespread use of artemisinin-based combination therapy (ACT and long-lasting insecticide-treated nets (LLINs. However, the occurrence of malaria resurgences, the loss of immunity of exposed populations constitute among other factors, serious concerns about the future of malaria elimination efforts. This study investigated the evolution of malaria morbidity in Dielmo (Senegal before and after the implementation of LLINs.A longitudinal study was carried out in Dielmo over eight years, from July 2007 to July 2015. In July 2008, LLINs were offered to all villagers, and in July 2011 and August 2014 the LLINs were renewed. A survey on LLINs use was done each quarter of the year. Thick smears stained with Giemsa, a rapid diagnostic test (RDT and quantitative polymerase chain reaction (PCR methods were performed for all cases of fever to assess malaria clinical attacks. Malaria cases were treated with ACT since June 2006.Malaria morbidity has decreased significantly since the implementation of LLINs in Dielmo, together with ACT. However, malaria resurgences have occurred twice during the seven years of LLINs use. These resurgences occurred the first time during the third year after the introduction of LLINs (aIRR (adjusted incidence-rate ratio [95%CI] = 5.90 [3.53; 9.88] p< 0.001 and a second time during the third year after the renewal of LLINs (aIRR [95%CI] = 5.60 [3.34; 9.39] p< 0.001. Sixty-nine percent (69% of the nets tested for their long-lasting insecticidal activity remained effective after 3 years of use.Good management of malaria cases by the use of ACT as first-line treatment against malaria in addition to the use of LLINs has significantly reduced malaria in Dielmo and allowed to reach the phase of pre-elimination of the disease. However, the occurrence of malaria resurgences raised serious concerns about malaria elimination, which would require additional

  2. What is case management in palliative care? An expert panel study

    NARCIS (Netherlands)

    van der Plas, A.G.M.; Onwuteaka-Philipsen, B.D.; van de Watering, M.; Jansen, W.J.J.; Vissers, K.C.; Deliens, L.

    2012-01-01

    Background: Case management is a heterogeneous concept of care that consists of assessment, planning, implementing, coordinating, monitoring, and evaluating the options and services required to meet the client's health and service needs. This paper describes the result of an expert panel procedure

  3. Religious socialization and non-religious volunteering: A Dutch panel study

    NARCIS (Netherlands)

    Vermeer, P.A.D.M.; Scheepers, P.L.H.

    2012-01-01

    Despite the fact that churches are still important sources of social capital in the Netherlands, the ongoing secularization of Dutch society has as yet not resulted in a drop of non-religious volunteering. In order to account for this apparent paradox, panel data are used to test the hypothesis that

  4. Simulation study of air and water cooled photovoltaic panel using ANSYS

    Science.gov (United States)

    Syafiqah, Z.; Amin, N. A. M.; Irwan, Y. M.; Majid, M. S. A.; Aziz, N. A.

    2017-10-01

    Demand for alternative energy is growing due to decrease of fossil fuels sources. One of the promising and popular renewable energy technology is a photovoltaic (PV) technology. During the actual operation of PV cells, only around 15% of solar irradiance is converted to electricity, while the rest is converted into heat. The electrical efficiency decreases with the increment in PV panel’s temperature. This electrical energy is referring to the open-circuit voltage (Voc), short-circuit current (Isc) and output power generate. This paper examines and discusses the PV panel with water and air cooling system. The air cooling system was installed at the back of PV panel while water cooling system at front surface. The analyses of both cooling systems were done by using ANSYS CFX and PSPICE software. The highest temperature of PV panel without cooling system is 66.3 °C. There is a decrement of 19.2% and 53.2% in temperature with the air and water cooling system applied to PV panel.

  5. Religious Socialization and Non-Religious Volunteering: A Dutch Panel Study

    NARCIS (Netherlands)

    Vermeer, P.; Scheepers, P.

    2011-01-01

    Abstract Despite the fact that churches are still important sources of social capital in the Netherlands, the ongoing secularization of Dutch society has as yet not resulted in a drop of non-religious volunteering. In order to account for this apparent paradox, panel data are used to test the

  6. Panel Conditioning in Longitudinal Studies: Evidence from Labor Force Items in the Current Population Survey

    Science.gov (United States)

    Halpern-Manners, Andrew; Warren, John Robert

    2013-01-01

    Does participating in a longitudinal survey affect respondents’ answers to subsequent questions about their labor force characteristics? In this article, we investigate the magnitude of “panel conditioning” or “time in survey” biases for key labor force questions in the monthly Current Population Survey (CPS). Using linked CPS records for household heads first interviewed between January 2007 and June 2010, our analyses are based on strategic within-person comparisons across survey months and between-person comparisons across CPS rotation groups. We find considerable evidence for panel conditioning effects in the CPS. Panel conditioning downwardly biases the CPS-based unemployment rate, mainly by leading people to remove themselves from its denominator. Across surveys, CPS respondents (claim to) leave the labor force in greater numbers than otherwise equivalent respondents who are participating in the CPS for the first time. The results cannot be attributed to panel attrition or mode effects. We discuss implications for CPS-based research and policy as well as for survey methodology more broadly. PMID:22893185

  7. Understanding repetitive travel mode choices in a stable context: A panel study approach

    DEFF Research Database (Denmark)

    Thøgersen, John

    2006-01-01

    It is argued that most travel mode choices are repetitive and made in a stable context. As an example, the everyday use of public transport is analyzed based on a panel survey with a random sample of about 1300 Danish residents interviewed up to three times in the period 1998-2000. The use...

  8. Vote recall: a panel study on the mechanisms that explain vote recall inconsistency

    NARCIS (Netherlands)

    van Elsas, E.J.; Lubbe, R.; van der Meer, T.W.G.; van der Brug, W.

    2014-01-01

    Voters’ recall of past behavior is known to be inaccurate. Yet, owing to data limitations, the precise mechanisms behind recall inconsistency have not yet been pulled apart empirically. We analyze the Dutch 1VOP panel data set (29,955 respondents, 53 waves) to simultaneously test four explanations

  9. A pilot study of serum microRNAs panel as potential biomarkers for diagnosis of nonalcoholic fatty liver disease.

    Directory of Open Access Journals (Sweden)

    Youwen Tan

    Full Text Available The invasive nature of liver biopsy makes the histopathological diagnosis of non-alcoholic fatty liver disease (NAFLD difficult and its diagnostic performance unsatisfactory. The present study aimed to identify a serum microRNA (miRNA expression profile that could serve as a novel diagnostic biomarker for NAFLD.Serum miRNA expression was investigated using three cohorts comprising 465 participants (healthy controls and NAFLD patients recruited between August 2010 and June 2013. miRNA expression was initially screened by Illumina sequencing using serum samples pooled from 20 patients and 20 controls. Quantitative reverse transcriptase polymerase chain reaction assay was then used to evaluate the expression of selected miRNAs. A logistic regression model was constructed using a training cohort (n = 242 and validated using another cohort (n = 183. The area under the receiver operating characteristic curve (AUC was used to evaluate diagnostic accuracy.We identified an miRNA panel (hsa-miR-122-5p, hsa-miR-1290, hsa-miR-27b-3p, and hsa-miR-192-5p with a high diagnostic accuracy for NAFLD. The satisfactory diagnostic performance of the miRNA panel remained regardless of the NAFLD activity score (NAS status. There was significant difference between the AUC values of the miRNA panel and those of ALT (AUC = 0.786, 95% CI = 0.717-0.855; P = 0.142 and FIB-4 (AUC = 0.795, 95% CI = 0.730-0.860; sensitivity = 69.9%, specificity = 83.7%.We identified a serum microRNA panel with considerable clinical value in NAFLD diagnosis. The results indicate that the miRNA panel is a more sensitive and specific biomarker for NAFLD than ALT and FIB-4.

  10. Secondary Education and Health Outcomes in Young People from the Cape Area Panel Study (CAPS)

    Science.gov (United States)

    2016-01-01

    Aim Education is one of the strongest social determinants of health, yet previous literature has focused on primary education. We examined whether there are additional benefits to completing upper secondary compared to lower secondary education in a middle-income country. Methods We performed a longitudinal analysis of the Cape Area Panel Study, a survey of adolescents living in South Africa. We undertook causal modeling using structural marginal models to examine the association between level of education and various health outcomes, using inverse probability weighting to control for sex, age, ethnicity, home language, income, whether employed in past year, region of birth, maternal educational status, marital status, whether currently pregnant and cognitive ability. Educational attainment was defined as primary (grades 1–7), lower secondary (grades 8–9) or upper secondary (grades 10–12). Results Of 3,432 participants, 165 (4.8%) had completed primary education, 646 (18.8%) lower secondary and 2,621 (76.3%) upper secondary. Compared to those completing lower secondary, males completing upper secondary education were less likely to have a health problem (OR 0.49; 95%CI 0.27–0.88; p = 0.02); describe their health as poor (0.52; 0.29–0.95; p = 0.03) or report that health interferes with daily life (0.54; 0.29–0.99; p = 0.047). Females were less likely to have been pregnant (0.45; 0.33–0.61; peducation and alcohol use, psychological distress, obesity, increased waist circumference or hypertension. Conclusion Completing upper secondary education was associated with improved health outcomes compared with lower secondary education. Expanding upper secondary education offers middle-income countries an effective way of improving adolescent health. PMID:27280408

  11. Secondary Education and Health Outcomes in Young People from the Cape Area Panel Study (CAPS).

    Science.gov (United States)

    Ward, Joseph L; Viner, Russell M

    2016-01-01

    Education is one of the strongest social determinants of health, yet previous literature has focused on primary education. We examined whether there are additional benefits to completing upper secondary compared to lower secondary education in a middle-income country. We performed a longitudinal analysis of the Cape Area Panel Study, a survey of adolescents living in South Africa. We undertook causal modeling using structural marginal models to examine the association between level of education and various health outcomes, using inverse probability weighting to control for sex, age, ethnicity, home language, income, whether employed in past year, region of birth, maternal educational status, marital status, whether currently pregnant and cognitive ability. Educational attainment was defined as primary (grades 1-7), lower secondary (grades 8-9) or upper secondary (grades 10-12). Of 3,432 participants, 165 (4.8%) had completed primary education, 646 (18.8%) lower secondary and 2,621 (76.3%) upper secondary. Compared to those completing lower secondary, males completing upper secondary education were less likely to have a health problem (OR 0.49; 95%CI 0.27-0.88; p = 0.02); describe their health as poor (0.52; 0.29-0.95; p = 0.03) or report that health interferes with daily life (0.54; 0.29-0.99; p = 0.047). Females were less likely to have been pregnant (0.45; 0.33-0.61; psex under 16 was also less likely (males 0.63; 0.44-0.91; p = 0.01; females 0.39; 0.26-0.58; peducation and alcohol use, psychological distress, obesity, increased waist circumference or hypertension. Completing upper secondary education was associated with improved health outcomes compared with lower secondary education. Expanding upper secondary education offers middle-income countries an effective way of improving adolescent health.

  12. Hepatitis Panel

    Science.gov (United States)

    ... others, the virus can cause long-term, chronic liver disease . Hepatitis C is most often spread by contact with infected ... contact with an infected person. Many people with hepatitis C develop chronic liver disease and cirrhosis . A hepatitis panel includes tests for ...

  13. Perinatal exposure to dioxins and dioxin-like compounds and infant growth and body mass index at seven years

    DEFF Research Database (Denmark)

    Iszatt, N.; Stigum, H; Govarts, Eva

    2016-01-01

    Background Dioxins and dioxin-like compounds are endocrine disrupting chemicals (EDCs). Experimental studies suggest perinatal exposure to EDCs results in later obesity. However, the few epidemiological investigations on dioxins are inconclusive. We investigated perinatal exposure to dioxins...

  14. An Investigation of Determinants Global Entrepreneurship: Multi-Country Panel Studies

    Directory of Open Access Journals (Sweden)

    Riznaldi Akbar

    2016-06-01

    Full Text Available This study examines the validity of governmental supports and policies; and financing for entrepreneurs in the context of global entrepreneurial activities. Our studies are based on the rich datasets of the Global Entrepreneurship Monitor (GEM database covering 108 countries from 2001 to 2014. In this study, we examine whether countries with more favorable policies and supports towards entrepreneurship and availability of financing for entrepreneurs would result in the higher country’s entrepreneurial activities. We use total early-stage entrepreneurial activity (TEA, a percentage of 18 - 64 year old population who are either a nascent entrepreneur or an owner manager of a new business, as our dependent variable to represent country’s entrepreneurial activities. There are two main explanatory variables used in the study: governmental supports and financing for entrepreneurs. The governmental supports represents the extent to which public policies support entrepreneurship as a relevant economic issue, while financing for entrepreneurs indicates the availability of financial resources for small and medium enterprises (SMEs including grants and subsidies. We also include three control variables of basic school entrepreneurial education and training; physical and services infrastructure; and cultural and social norms to test the significance of these factors to the country’s entrepreneurial activities. This study adopts panel regression model augmented with control variables. We favor Random Effect model as opposed to Fixed Effect or Pooled OLS model as Hausman and Breusch–Pagan test suggest. Our results suggest that there is no evident that government supports have significant contribution to country’s entrepreneurial activities.  In other words, entrepreneurial activities are more flourished in a country that has not set entrepreneurship as relevant economic issues as it might be the case for many emerging countries. The availability of

  15. Immediate and long-term efficacy and safety of photodynamic therapy with Photolon (Fotolon): a seven-year clinical experience

    Science.gov (United States)

    Istomin, Yuri P.; Kaplan, Michael A.; Shliakhtsin, Siarhei V.; Lapzevich, Tatsiana P.; Cerkovsky, Dmitriy A.; Marchanka, Ludmila N.; Fedulov, Alexander S.; Trukhachova, Tatsiana V.

    2009-06-01

    The purpose of the present study was to summarize data on the long-term efficacy of photodynamic therapy (PDT) with Photolon in patients with malignant tumors of various types and localizations. The data obtained show that PDT with Photolon is a highly effective therapeutic modality for the treatment of skin tumors, cervical intraepithelial neoplasias, lung cancers, disseminated forms of melanoma, primary and metastatic brain tumors, several ophthalmologic diseases. This paper provides a review of most illustrative studies of the application of PDT with Photolon for the treatment of different oncological and non-oncological diseases performed in leading clinical centers of the Republic of Belarus and Russia.

  16. Structure and biomass production of one- to seven-year-old intensively cultured jack pine plantation in Wisconsin.

    Science.gov (United States)

    J. Zavitkovski; David H. Dawson

    1978-01-01

    Spacing and rotation length effects were studied for 7 years in intensively cultured jack pine stands. Production culminated at age 5 in the densest planting and progressively later in more open spacing. Biomass production was two to several times higher than in jack pine plantations grown under traditional silvicultural systems.

  17. Factors associated with attrition in a longitudinal online study: results from the HaBIDS panel.

    Science.gov (United States)

    Rübsamen, Nicole; Akmatov, Manas K; Castell, Stefanie; Karch, André; Mikolajczyk, Rafael T

    2017-08-31

    Knowing about predictors of attrition in a panel is important to initiate early measures against loss of participants. We investigated attrition in both early and late phase of an online panel with special focus on preferences regarding mode of participation. We used data from the HaBIDS panel that was designed to investigate knowledge, attitudes, and practice regarding infections in the German general population. HaBIDS was divided into two phases: an initial phase when some participants could choose their preferred mode of participation (paper-and-pencil or online) and an extended phase when participants were asked to become members of an online panel that was not limited regarding its duration (i.e. participants initially preferring paper questionnaires switched to online participation). Using competing risks regression, we investigated two types of attrition (formal withdrawal and discontinuation without withdrawal) among online participants, separately for both phases. As potential predictors of attrition, we considered sociodemographic characteristics, physical and mental health as well as auxiliary information describing the survey process, and, in the extended phase, initial mode preference. In the initial phase, higher age and less frequent Internet usage predicted withdrawal, while younger age, higher stress levels, delay in returning the consent form, and need for receiving reminder emails predicted discontinuation. In the extended phase, only need for receiving reminder emails predicted discontinuation. Numbers of withdrawal in the extended phase were too small for analysis. Initial mode preference did not predict attrition in the extended phase. Besides age, there was no evidence of differential attrition by sociodemographic factors in any phase. Predictors of attrition were similar in both phases of the panel, but they differed by type of attrition (withdrawal vs. discontinuation). Sociodemographic characteristics only played a minor role for both

  18. Changes in the fish community and water quality during seven years of stocking piscivorous fish in a shallow lake

    DEFF Research Database (Denmark)

    Skov, Christian; Perrow, M.R.; Berg, Søren

    2002-01-01

    1. Piscivores (annual stocking of 1000 individuals ha(-1) of 0+ pike and a single stocking of 30 kg ha(-1) of large 20-30 cm perch) were stocked in seven consecutive years in a shallow eutrophic lake in Denmark. The stocking programme aimed at changing food-web structure by reducing......) declined distinctly during the study period. This effect was attributed to predation by large (>50 cm) pike. Based on scale readings, we cautiously suggest that the stocking of 0+ pike boosted the adult pike population to produce an unexpected impact in later years. Conversely, no direct impact of stocked...... community, although the relationships were not straightforward. 6. This 7-year study indicates that piscivorous fish may be a significant structuring force in shallow eutrophic lakes, suggesting that stocking piscivores can increase predation pressure on cyprinids. However, the general lack of impact of 0...

  19. Changes in the fish community and water quality during seven years of stocking piscivorous fish in a shallow lake

    DEFF Research Database (Denmark)

    Skov, Christian; Perrow, M.R.; Berg, Søren

    2002-01-01

    community, although the relationships were not straightforward. 6. This 7-year study indicates that piscivorous fish may be a significant structuring force in shallow eutrophic lakes, suggesting that stocking piscivores can increase predation pressure on cyprinids. However, the general lack of impact of 0......1. Piscivores (annual stocking of 1000 individuals ha(-1) of 0+ pike and a single stocking of 30 kg ha(-1) of large 20-30 cm perch) were stocked in seven consecutive years in a shallow eutrophic lake in Denmark. The stocking programme aimed at changing food-web structure by reducing......) declined distinctly during the study period. This effect was attributed to predation by large (>50 cm) pike. Based on scale readings, we cautiously suggest that the stocking of 0+ pike boosted the adult pike population to produce an unexpected impact in later years. Conversely, no direct impact of stocked...

  20. Seven-Year Evaluation of Insecticide Tools for Emerald Ash Borer in Fraxinus pennsylvanica (Lamiales: Oleaceae) Trees.

    Science.gov (United States)

    Bick, Emily N; Forbes, Nora J; Haugen, Christopher; Jones, Grant; Bernick, Shawn; Miller, Fredric

    2018-04-02

    Emerald ash borer (EAB), Agrilus planipennis (Fairmaire; Coleoptera: Buprestidae), is decimating ash trees (Fraxinus spp.) in North America. Combatting EAB includes the use of insecticides; however, reported insecticide efficacy varies among published studies. This study assessed the effects of season of application, insecticide active ingredient, and insecticide application rate on green ash (Fraxinus pennsylvanica Marsh.) (Lamiales: Oleaceae) canopy decline caused by EAB over a 5- to 7-yr interval. Data suggested that spring treatments were generally more effective in reducing canopy decline than fall treatments, but this difference was not statistically significant. Lowest rates of decline (<5% over 5 yr) were observed in trees treated with imidacloprid injected annually in the soil during spring (at the higher of two tested application rates; 1.12 g/cm diameter at 1.3 m height) and emamectin benzoate injected biennially into the stem. All tested insecticides (dinotefuran, emamectin benzoate, and imidacloprid) under all tested conditions significantly reduced the rate of increase of dieback.

  1. Four-year to seven-year outcomes of advanced surface ablation with excimer laser for high myopia

    DEFF Research Database (Denmark)

    Hansen, Rasmus Søgaard; Lyhne, Niels; Grauslund, Jakob

    2015-01-01

    Purpose: To evaluate and compare long-term outcomes ofafter photorefractive keratectomy with cooling (cPRK) and laser-assisted subepithelial keratectomy (LASEK) for high myopia. Methods: Retrospective single-masked follow-up study of patients treated for myopia between 2007 and 2009 with c......PRK or LASEK, using a high-frequency flying-spot excimer laser with eye-tracker (MEL80; Carl Zeiss, Jena, Germany). One eye of each patient was randomly chosen for analysis. Re-treated eyes were excluded. Results: Forty-six cPRK patients and 35 LASEK patients were included. Spherical equivalent averaged -7...

  2. Seven years of cyanide ingestions in the USA: critically ill patients are common, but antidote use is not.

    Science.gov (United States)

    Bebarta, Vikhyat S; Pitotti, Rebecca L; Borys, Doug J; Morgan, David L

    2011-02-01

    Cyanide is a common toxin in structural fires and a salt that is ingested for suicide. However, most studies have focused on the effects of inhaled cyanide. The objective of this study was to describe the incidence of cyanide ingestions, symptoms, cardiac arrest and antidotal therapy used as reported to all US poison centres over 7 years. A retrospective review of cases over 7 years as reported to 61 poison centres in the USA was performed. Sole ingestions of cyanide were identified. A trained reviewer used a standard data collection sheet within a secured electronic database. Age, intent, clinical effects, treatments, antidotes and outcomes were recorded. One investigator audited a random sample of charts. Out of 1741 exposures, 435 ingestions were identified. Most were male (68%) and the mean age was 34 years (range 1 month-83 years). 45% of cases were intentional, most commonly as a suicide attempt. 8.3% of cases died and 9% (38/435) of patients had cardiac arrest or hypotension. 13% of all cases and 26% of cases arriving at a healthcare facility received an antidote. In 35% of cases of cardiac arrest or hypotension, and in 74% of intentional ingestions, antidotes were not given. Suicide attempt was the most common reason for cyanide ingestion. Most of these patients died. Cardiac arrest or hypotension was common, but antidote use was not, particularly in critically ill patients. Research is needed to improve outcomes of cyanide-induced hypotension and cardiac arrest and to reduce barriers to antidote use.

  3. Assessing type I error and power of multistate Markov models for panel data-A simulation study

    OpenAIRE

    Cassarly, Christy; Martin, Renee’ H.; Chimowitz, Marc; Peña, Edsel A.; Ramakrishnan, Viswanathan; Palesch, Yuko Y.

    2016-01-01

    Ordinal outcomes collected at multiple follow-up visits are common in clinical trials. Sometimes, one visit is chosen for the primary analysis and the scale is dichotomized amounting to loss of information. Multistate Markov models describe how a process moves between states over time. Here, simulation studies are performed to investigate the type I error and power characteristics of multistate Markov models for panel data with limited non-adjacent state transitions. The results suggest that ...

  4. The dynamic interaction of personal norms and environment-friendly buying behavior: A panel study

    DEFF Research Database (Denmark)

    Thøgersen, John; Ølander, Folke

    2006-01-01

    A deeper understanding of the attitude-norm-behavior relationship in the environmental field can be obtained by analyzing the dynamic interaction over time between relevant attitudinal variables and specific behaviors of interest. This article is based on a panel survey with a random sample...... of about 1,500 Danes interviewed up to 3 times in 1998 to 2000, regarding their purchase of organic food products. The panel analysis reveals that the stronger are consumers' personal norms about buying organic food products and the less they perceive organic products as expensive, the greater...... the likelihood that they change their purchase patterns in favor of organic products. Furthermore, one can observe significant cross-lagged paths from past behavior to belief and norm variables....

  5. Experimental study of discharging PCM ceiling panels through nocturnal radiative cooling

    DEFF Research Database (Denmark)

    Bourdakis, Eleftherios; Péan, Thibault Q.; Gennari, Luca

    2016-01-01

    PhotoVoltaic/Thermal (PV/T) panels were used for cooling water through the principle of nocturnal radiative cooling. This water was utilised for discharging Phase Change Material (PCM) which was embedded in ceiling panels in a climate chamber. Three different sets of flow rates were examined...... for the solar and the PCM loops, for five days each. The highest examined water flow rate (210 l/h) in the PCM loop provided the best thermal environment in the climate chamber, namely 92% of the occupancy time was within the range of Category III of Standard EN 15251. Although the lowest examined water flow...... rate (96 l/h) in the solar loop provided the highest average cooling power, due to the significant variations in the weather conditions during the three experimental cases, made it impossible to determine to which extent the difference in the cooling power is due to the different water flow rate...

  6. Seven-Year Course of Borderline Personality Disorder Features: Borderline Pathology Is as Unstable as Depression during Adolescence.

    Science.gov (United States)

    Conway, Christopher C; Hipwell, Alison E; Stepp, Stephanie D

    2017-07-01

    Borderline personality disorder (PD) historically is construed as an unremitting condition with poor prognosis. The present study takes a new approach to examining stability and change in borderline PD by explaining symptom expression in terms of an unchanging foundation-termed borderline proneness-on one hand, and transitory influences on the other. We monitored borderline PD symptoms annually in a large sample of high-risk adolescent girls ( N = 2,450) from ages 14 to 20. Trait-state-occasion modeling revealed that just over half (52-57%) of borderline PD symptom variation was attributable to fixed borderline proneness, whereas the remainder was subject to change across yearly measurement occasions. This degree of stability was no larger than the corresponding estimate for depression, a condition known for its variable course. Our results indicate that, contrary to its reputation, borderline pathology is not set in stone, and it fluctuates in response to situational influences.

  7. Corneal Cross-linking to Halt the Progression of Keratoconus and Corneal Ectasia: Seven-Year Follow-up.

    Science.gov (United States)

    O'Brart, David P S; Patel, Parul; Lascaratos, Gerassimos; Wagh, Vijay K; Tam, Connan; Lee, Jennifer; O'Brart, Naomi A

    2015-12-01

    To determine long-term efficacy and safety of riboflavin/ultraviolet A corneal cross-linking (CXL). Prospective cohort study. Thirty-six patients (36 eyes) who underwent epithelium-off CXL at a University Hospital (Guy's and St Thomas' National Health Service Foundation Trust) 6-8 years previously were examined. The main outcome measures were refractive error, visual acuity, corneal topographic keratometry, ultrasonic pachymetry, and topography-derived corneal wavefront. At 7 years compared to preoperative values, mean spherical equivalent refractive error (SEQ) increased by +0.78 diopter (D) (P corneal cross-linking, improvements in topographic and wavefront parameters evident at 1 year were seen to continue to improve at 5 years and were maintained at 7 years. No treated eyes progressed over the 7-year follow-up period. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Temporal-Spatial Evolution of Groundwater Nitrogen Pollution Over Seven Years in a Highly Urbanized City in the Southern China.

    Science.gov (United States)

    He, Xiaorui; Qian, Jiazhong; Liu, Zufa; Lu, Yuehan; Ma, Lei; Zhao, Weidong; Kang, Bo

    2017-12-01

    Understanding the temporospatial variation in nitrogen pollution in groundwater and the associated controlling factors is important to establish management practices that ensure sustainable use of groundwater. In this study, we analyzed inorganic nitrogen content (nitrate, nitrite, and ammonium) in 1164 groundwater samples from shallow, middle-deep, and deep aquifers in Zhanjiang, a highly urbanized city in the southern China. Our data span a range of 7 years from 2005 to 2011. Results show that shallow aquifers had been heavily contaminated by nitrate and ammonium. Temporal patterns show that N contamination levels remained high and relatively stable over time in urban areas. This stability and high concentration is hypothesized as a result of uncontrolled, illicit sewer discharges from nearby business facilities. Groundwater in urban land and farmland displays systematic differences in geochemical characteristics. Collectively, our findings demonstrate the importance of continuously monitoring groundwater quality and strictly regulating sewage discharges in Zhanjiang.

  9. Multiple perpetrator rape among girls evaluated at a hospital-based child advocacy center: seven years of reviewed cases.

    Science.gov (United States)

    Edinburgh, Laurel; Pape-Blabolil, Julie; Harpin, Scott B; Saewyc, Elizabeth

    2014-09-01

    The aim of this study was to describe contextual events, abuse experiences, and disclosure processes of adolescents who presented to a hospital-based Child Advocacy Center for medical evaluation and evidentiary collection as indicated after experiencing multiple perpetrator rape during a single event (n=32) and to compare these findings to a group of single perpetrator sexual assaults (n=534). This study used a retrospective mixed-methods design with in-depth, forensic interviews and complete physical examinations of gang-raped adolescents. Patients ranged from 12 to 17 years (M=14 years). Girls who experienced multiple perpetrator rape during a single event were more likely to have run away, to have drunk alcohol in the past month, and to have participated in binge drinking in the past 2 weeks. Acute presentation of these victims were rare but 30% had hymenal transections and 38% had sexually transmitted infections (STIs). Forensic interviews revealed alcohol was a common weapon used by offenders, and its use resulted in victims experiencing difficulty in remembering and reporting details for police investigation or physical and mental health care. Most victims were raped at parties they attended with people they thought they could trust, and they felt let down by witnesses who could have helped but did not intervene. Although relatively rare, multiple perpetrator rape during a single event is a type of severe sexual assault experience and has significant risks for deleterious health outcomes. These victims require health care by trained providers to diagnose physical findings, treat STIs, screen for trauma, and support victims. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  10. A Parametric Study of Thermal Performance of an Exterior Wall Insulated with Vacuum Insulation Panels

    OpenAIRE

    Ciobanu, Adrian-Alexandru; Iacob, Adrian

    2013-01-01

    The requirements regarding thermal insulation of the new buildings and thermal rehabilitation of the existing buildings tend to reach a threshold of insulation which allows to fulfill the necessary requirements for a low-energy building. To achieve this level of thermal insulation involves using either thick layers of conventional insulation (polystyrene, mineral wool, etc.) or high thermal performance materials. Vacuum insulation panels are high performance thermal insulation characteri...

  11. A Comparative Study on a Built Sun Tracker and Fixed Converter Panels

    OpenAIRE

    Farzin Shama; Gholam Hossein Roshani; Sobhan Roshani; Arash Ahmadi; Saber Karami

    2012-01-01

    Producing non-polluting renewable energy in large scale is essential for sustainability of future developments in industry and human society. Among renewable energy resources, solar energy takes a special place because of its free accessibility and affordability. However, the optimization of its production and consumption processes poses important concerns, essentially in the affordability issue. This paper investigates several optimization and performance issues regarding solar panel convert...

  12. The Effect of Minimum Wages on Youth Employment in Canada: A Panel Study.

    Science.gov (United States)

    Yuen, Terence

    2003-01-01

    Canadian panel data 1988-90 were used to compare estimates of minimum-wage effects based on a low-wage/high-worker sample and a low-wage-only sample. Minimum-wage effect for the latter is nearly zero. Different results for low-wage subgroups suggest a significant effect for those with longer low-wage histories. (Contains 26 references.) (SK)

  13. Seven-year surveillance of emm types of pediatric Group A streptococcal pharyngitis isolates in Western Greece.

    Directory of Open Access Journals (Sweden)

    George A Syrogiannopoulos

    Full Text Available BACKGROUND: An experimental 26-valent M protein Group A streptococcal (GAS vaccine has entered clinical studies. Pharyngeal GAS emm type surveillances in different areas and time-periods enhance the understanding of the epidemiology of GAS pharyngitis. Moreover, these surveillances, combined with the data on GAS invasive disease, can play a significant role in the formulation of multivalent type-specific vaccines. METHODS: During a 7-year period (1999-2005, 2408 GAS isolates were recovered from consecutive children with pharyngitis in Western Greece. The overall macrolide resistance rate was 22.8%. Along the study period we noted a tendency towards significantly decreased rates of resistance, with the lowest rates occurring in 2002 (15.3%, 2003 (15% and 2004 (16.7%. A random sample of isolates from each year, 338 (61.7% of the 548 macrolide-resistant and 205 (11% of the macrolide-susceptible, underwent molecular analysis, including emm typing. RESULTS: The 543 typed isolates had 28 different emm types. A statistically significant association was found between macrolide resistance and emm4, emm22 and emm77, whereas emm1, emm3, emm6, emm12, emm87 and emm89 were associated with macrolide susceptibility. A significant yearly fluctuation was observed in emm4, emm28 and emm77. The most common macrolide-resistant GAS were emm77 isolates harboring erm(A, either alone or in combination with mef(A, emm4 carrying mef(A, emm28 possessing erm(B, emm75 carrying mef(A, emm12 harboring mef(A and emm22 carrying erm(A. We estimated that 82.8% of the isolates belonged to emm types included in the novel 26-valent M protein vaccine. The vaccine coverage rate was determined mainly by the increased frequency of nonvaccine emm4 isolates. CONCLUSIONS: A limited number of emm types dominated among macrolide-susceptible and macrolide-resistant GAS isolates. We observed seasonal fluctuations, which were significant for emm4, emm28 and emm77. This type of data can serve as

  14. Conditional models accounting for regression to the mean in observational multi-wave panel studies on alcohol consumption.

    Science.gov (United States)

    Ripatti, Samuli; Mäkelä, Pia

    2008-01-01

    To develop statistical methodology needed for studying whether effects of an acute-onset intervention differ by consumption group that accounts correctly for the effect of regression to the mean (RTM) in observational panel studies with three or more measurement waves. A general statistical modelling framework, based on conditional models, is presented for analysing alcohol panel data with three or more measurements, that models the dependence between initial drinking level and change in consumption controlling for RTM. The method is illustrated by panel data from Finland, southern Sweden and Denmark, where the effects of large changes in alcohol taxes and travellers' allowances were studied. The suggested model allows for drawing statistical inference of the parameters of interest and also the identification of non-linear effects of an intervention by initial consumption using standard statistical software modelling tools. There was no evidence in any of the countries of the changes being larger among heavy drinkers, but in southern Sweden there was evidence that light drinkers raised their level of consumption. Conditional models are a versatile modelling framework that offers a flexible tool for modelling and testing changes due to intervention in consumption by initial consumption while controlling simultaneously for RTM.

  15. Seven years of aerosol scattering hygroscopic growth measurements from SGP: Factors influencing water uptake: Aerosol Scattering Hygroscopic Growth

    Energy Technology Data Exchange (ETDEWEB)

    Jefferson, A. [Cooperative Institute of Research in the Environmental Sciences, University of Colorado Boulder, Boulder Colorado USA; Earth Systems Research Laboratory, National Oceanic and Atmospheric Administration, Boulder Colorado USA; Hageman, D. [Cooperative Institute of Research in the Environmental Sciences, University of Colorado Boulder, Boulder Colorado USA; Earth Systems Research Laboratory, National Oceanic and Atmospheric Administration, Boulder Colorado USA; Morrow, H. [Earth Systems Research Laboratory, National Oceanic and Atmospheric Administration, Boulder Colorado USA; Science and Technology Corporation, Boulder Colorado USA; Mei, F. [Pacific Northwest National Laboratory, Richland Washington USA; Watson, T. [Brookhaven National Laboratory, Upton New York USA

    2017-09-11

    Long-term measurements of changes in the aerosol scattering coefficient hygroscopic growth at the U.S. Department of Energy Southern Great Plains site provide information on the seasonal as well as size and chemical dependence of aerosol hygroscopic growth. Annual average sub 10 um fRH values (the ratio of aerosol scattering at 85%/40% RH) were 1.75 and 1.87 for the gamma and kappa fit algorithms, respectively. The study found higher growth rates in the winter and spring seasons that correlated with high aerosol nitrate mass fraction. FRH, exhibited strong, but differing correlations with the scattering Ångström exponent and backscatter fraction, two optical size-dependent parameters. The aerosol organic fraction had a strong influence, with fRH decreasing with increases in the organic mass fraction and absorption Ångström exponent and increasing with the aerosol single scatter albedo. Uncertainty analysis if the fit algorithms revealed high uncertainty at low scattering coefficients and slight increases in uncertainty at high RH and fit parameters values.

  16. Improving compliance with Intersocietal Accreditation Commission (IAC) reporting standards: A serial comparison of 523 labs over seven years.

    Science.gov (United States)

    Maddux, P Timothy; Farrell, Mary Beth; Ewing, Joseph A; Tilkemeier, Peter L

    2017-05-04

    The aim of this study was to evaluate reporting compliance of laboratories applying for serial accreditation by the Intersocietal Accreditation Commission (IAC) and compare compliance based on laboratory characteristics. All laboratories applying for IAC accreditation for the first time in 2008 and then twice more (2011-2014) were evaluated for compliance with 18 reporting elements. The elements were ranked into three severity groups (high/moderate/low). Reports from 523 laboratories were evaluated. The percentage of laboratories with reporting issues by cycle was 66.2% for cycle 1, 36.7% for cycle 2, and 43.8% for cycle 3 (p < .001). For most of the 18 elements, there was a significant decrease in the percentage of labs with issues. Less moderate and high severity errors were seen over time. Also, the mean non-compliant elements per laboratory decreased from 5.78 ± 2.72 at cycle 1, down to 1.25 ± 1.77 at cycle 3. In facilities applying for 3 consecutive IAC accreditation cycles, reporting compliance with IAC Standards improved between cycles 1-2 and 1-3. No significant improvement occurred between cycles 2-3. Although the quality of reports improved overall, problems remain in quantifying myocardial perfusion defects, documenting report approval date, and integrating stress and imaging reports.

  17. A seven-year investigation of marital expectations and marriage among urban, low-income, African American adolescent mothers.

    Science.gov (United States)

    Oberlander, Sarah E; Agostini, Wendy R Miller; Houston, Avril Melissa; Black, Maureen M

    2010-02-01

    Welfare reform has targeted marriage promotion among low-income women. This study explores patterns of marital expectations and marriage among 181 urban, low-income, African American adolescent mothers and their mothers. Using PROC TRAJ to analyze developmental trajectories of adolescent mother-grandmother relationship quality over 24 months, we categorized relationships as either high or low support. We examined the effects of intergenerational marriage models and adolescent mother-grandmother relationship quality on marital expectations and marriage over the first 7 years postpartum. At 24 months, half (52%) of adolescent mothers expected to marry, but marital expectations did not predict marriage. Marital expectations were associated with concurrent involvement in a romantic relationship, not intergenerational marriage models or a supportive adolescent mother-grandmother relationship. After 7 years, 14% of adolescent mothers were married. Married mothers lived in families characterized by the joint effects of intergenerational marriage models and supportive adolescent mother-grandmother relationships. They were older and had more children than did single mothers, suggesting that they were in a family formation phase of life. Policies that promote the education and employment opportunities necessary to support a family are needed.

  18. Changes in the net carbon balance following a shelterwood harvest at Howland Forest in central Maine seven years after harvest

    Science.gov (United States)

    Scott, N. A.; Hollinger, D.; Davidson, E. A.; Rodrigues, C.; Hughes, H.; Lee, J. T.; Richardson, A. D.; Dail, B.

    2009-12-01

    As CO2 emissions continue to increase, policy-makers are considering various ways to help slow the rise in atmospheric CO2 concentrations. Forests exchange significant quantities of carbon with the atmosphere, so any measures that increase carbon storage in forests could help mitigate rising CO2 emissions. Some proposed C trading markets include payments for enhanced C storage due to changes in forest management, but others exclude management of existing forests due to large uncertainties in sequestration rates, validation, and leakage. Ideally, forest management practices could be designed to provide multiple benefits to society, including provision of wood and paper products, creating economic returns from natural resources, and sequestering C from the atmosphere. To evaluate the impact of a forest management practice on C storage, it is important to quantify both on-site and off-site C fluxes. We began studying changes in C sequestration following a shelterwood harvest at the Howland Forest in central Maine in 2000. Shelterwood harvesting removed about 30% of live aboveground biomass from the forest (15 Mg C ha-1), reduced leaf area by about 40%, and created detrital carbon pools of about 10.5 Mg C ha-1. Net ecosystem carbon storage (NEE), measured using eddy covariance, went from about 1.9 Mg C ha-1y-1 to almost zero in both 2003 and 2004. Live trees, however, stored about 1.5 Mg C ha-1y-1 in 2003 - this was only slightly lower than C storage in live vegetation in the control (unharvested) stand. In 2005, NEE increased to about 1.5 Mg C ha-1y-1 and tree growth increased to about 2.2 Mg C ha-1y-1 in spite of the fact that leaf-area index (LAI) remained about 25% lower in the harvested stand. Soil respiration was significantly lower in the harvested stand, but only in areas impacted heavily by harvest. This is likely due to decreased root respiration as a result of tree removal. When accounting for both on- and off-site carbon pools, this forest returned to being

  19. Comprehensive Management of Type 1 Diabetes in a Marginalized Population in Northern India: a Seven Year Retrospective Review

    Directory of Open Access Journals (Sweden)

    S Gupta

    2016-01-01

    Full Text Available Indian children with type 1 diabetes (T1D from resource-poor families often have poor prognoses due to unavailability or unaffordability of care. We utilized a team-based approach to treat marginalized T1D children with multiple daily insulin injection (MDI basal bolus regimen. In this study, a chart review of all 48 patients treated from 2006-2014 were included. A team-based approach comprising a physician, a diabetes educator and a community health worker were used. All patients were administered MDI of glargine and short-acting human insulin. Extensive diabetes self-management education tailored to culture, language, and literacy level was provided. Carbohydrate counting of local foods was introduced with patients utilizing home blood glucose monitoring. The structured program included home visits, telephone and internet support and group meetings. Age (Mean ± SD at enrolment was 13.9 ± 4.7 years (n=48, with 26 males (54%. For 25 patients followed for ≥ 3 years, HbA1c at baseline and years 1, 2 and 3 was (Mean ± SD 13.0 ± 1.0%, (119 ± 11 mmol/mol 9.0 ± 2.0% (75 ± 22 mmol/mol 8.2 ± 1.5% (66 ± 17 mmol/mol and 8.3 ± 1.4% (67 ± 15 mmol/mol, respectively and BMI improved from (Mean ± SD 15.4 ± 2.4 to 19.0 ± 2.9 kg/m2. The most recent median HbA1c for all patients was 8.6% (70 mmol/mol. There were no hospital readmissions with ketoacidosis or severe hypoglycemia, and one death from unknown causes. Integral to the program′s success was provision of essential diabetes supplies and intensive locally-relevant diabetes education, including innovative approaches such as an internet-based support group. Our findings suggest that it is feasible to achieve successful and sustainable T1D management in an indigent population in rural India.

  20. Joint preservation after hip arthroscopy in patients with FAI. Prospective analysis with a minimum follow-up of seven years

    Science.gov (United States)

    Comba, Fernando; Yacuzzi, Carlos; Ali, Pablo J.; Zanotti, Gerardo; Buttaro, Martin; Piccaluga, Francisco

    2016-01-01

    Summary Background The purpose of this study is to evaluate the clinical outcomes, radiological degenerative progression and the joint preservation rate in a series of patients with Femoroacetabular Impingement (FAI) treated with hip arthroscopy at a minimum follow-up of 7 years. The predictive factors for total hip arthroplasty (THA) requirement were analyzed. Materials and methods Between February 2008 and February 2009, 42 consecutive patients treated with hip arthroscopy due to FAI syndrome were included. There were 15 women and 27 men with an average age of 38 years (range 23 to 56 years). The surgery involved joint damage stabilization (labral tears and/or chondrolabral injuries) and correction of associated bony deformities (cam and/or pincer lesions). A prospective clinical follow-up was made with no patient lost. We specifically addressed the need for THA. Predictive factors for THA were also analyzed. Results At final follow up, joint preservation rate was 83.33% (CI 95% 68,64%–93,03%). Probability of evolving to a THA in patients with radiographic preoperative Tonnis grades 0 and I was of 0% (CI 95%: 0–12.77). Probability of evolving to a THA in patients with preoperative Tonnis grades II and III was 46,67% (CI 95%21.27%–73,41%). A statistically significant difference was present between both groups (p= 0.002). Patients older than 45 years at the time of hip arthroscopy were at significant risk of evolving to a THA (p=0.0012). Excluding those patients who undergone a THA: modified HHS was 88.25 points (80–96) and radiographic analysis addressed a 14,29% (IC95% 4,81%–30,26%) of progressive degenerative changes without affecting clinical results. Conclusions Hip arthroscopy for the treatment of patients with FAI syndrome showed favorable results regarding joint preservation. Patients with preoperative radiographic evidence of advanced-stage osteoarthritis and those older than 45 years at the time of surgery have higher risk of requiring THA

  1. Panel 5: Microbiology and immunology panel.

    Science.gov (United States)

    Murphy, Timothy F; Chonmaitree, Tasnee; Barenkamp, Stephen; Kyd, Jennelle; Nokso-Koivisto, Johanna; Patel, Janak A; Heikkinen, Terho; Yamanaka, Noboru; Ogra, Pearay; Swords, W Edward; Sih, Tania; Pettigrew, Melinda M

    2013-04-01

    The objective is to perform a comprehensive review of the literature from January 2007 through June 2011 on the virology, bacteriology, and immunology related to otitis media. PubMed database of the National Library of Medicine. Three subpanels with co-chairs comprising experts in the virology, bacteriology, and immunology of otitis media were formed. Each of the panels reviewed the literature in their respective fields and wrote draft reviews. The reviews were shared with all panel members, and a second draft was created. The entire panel met at the 10th International Symposium on Recent Advances in Otitis Media in June 2011 and discussed the review and refined the content further. A final draft was created, circulated, and approved by the panel. Excellent progress has been made in the past 4 years in advancing an understanding of the microbiology and immunology of otitis media. Advances include laboratory-based basic studies, cell-based assays, work in animal models, and clinical studies. The advances of the past 4 years formed the basis of a series of short-term and long-term research goals in an effort to guide the field. Accomplishing these goals will provide opportunities for the development of novel interventions, including new ways to better treat and prevent otitis media.

  2. Panel 5: Microbiology and Immunology Panel

    Science.gov (United States)

    Murphy, Timothy F.; Chonmaitree, Tasnee; Barenkamp, Stephen; Kyd, Jennelle; Nokso-Koivisto, Johanna; Patel, Janak A.; Heikkinen, Terho; Yamanaka, Noboru; Ogra, Pearay; Swords, W. Edward; Sih, Tania; Pettigrew, Melinda M.

    2014-01-01

    Objective The objective is to perform a comprehensive review of the literature from January 2007 through June 2011 on the virology, bacteriology, and immunology related to otitis media. Data Sources PubMed database of the National Library of Medicine. Review Methods Three subpanels with co-chairs comprising experts in the virology, bacteriology, and immunology of otitis media were formed. Each of the panels reviewed the literature in their respective fields and wrote draft reviews. The reviews were shared with all panel members, and a second draft was created. The entire panel met at the 10th International Symposium on Recent Advances in Otitis Media in June 2011 and discussed the review and refined the content further. A final draft was created, circulated, and approved by the panel. Conclusion Excellent progress has been made in the past 4 years in advancing an understanding of the microbiology and immunology of otitis media. Advances include laboratory-based basic studies, cell-based assays, work in animal models, and clinical studies. Implications for Practice The advances of the past 4 years formed the basis of a series of short-term and long-term research goals in an effort to guide the field. Accomplishing these goals will provide opportunities for the development of novel interventions, including new ways to better treat and prevent otitis media. PMID:23536533

  3. Seven years of geomorphic change in the head of Monterey Canyon, CA: Steady state equilibrium or monotonic change?

    Science.gov (United States)

    Smith, D. P.; Kvitek, R. G.; Ross, E.; Iampietro, P.; Paull, C. K.; Sandersfeld, M.

    2010-12-01

    The head of Monterey submarine canyon has been surveyed with high-precision multibeam sonar at least once each year since September 2002. This poster provides a summary of changes between September 2002 and September 2008. Data were collected with a variety of Reson mulitbeam sonar heads, and logged with an ISIS data acquisition system. Vessel attitude was corrected using an Applanix POS MV equipped with an auxillary C-Nav 2050 GPS receiver. Data were processed and filtered and cleaned in Caris HIPS. Depth changes for various time spans were determined through raster subtraction of pairs of 3-m resolution bathymetric grids in ArcMap. The depth change analyses focused on the canyon floor, except where a landslide occurred on a wall, and where obvious gullying near the headwall had occurred during the time of our study. Canyon walls were generally excluded from analysis. The analysis area was 1,414,240 sq meters. The gross changes between 2002 and 2008 include net erosion of 2,300,000 m^3 +/- 800,000 m^3 of material from the canyon. The annualized rate of net sediment loss from this time frame agrees within an order of magnitude with our previously published estimates from earlier (shorter) time frames, so the erosion events seem to be moderate magnitude and frequent, rather than infrequent and catastrophic. The greatest sediment loss appears to be from lateral erosion of channel-bounding terraces rather than deepening or scouring of the existing channel axis. A single landslide event that occurred in summer 2003 had an initial slide scar (void) volume of 71,000 m^3. The scar was observed to increase annually, and had grown to approximately 96,000 m^3 by 2008. The initial slide was too small to be tsunamigenic. In contrast to the monotonic canyon axis widening, the shoreward terminus of the canyon (canyon lip) appears to be in steady state equilibrium with sediment supply entering the canyon from the littoral zone. The lip position, indicated by the clearly defined

  4. Secondary Education and Health Outcomes in Young People from the Cape Area Panel Study (CAPS.

    Directory of Open Access Journals (Sweden)

    Joseph L Ward

    Full Text Available Education is one of the strongest social determinants of health, yet previous literature has focused on primary education. We examined whether there are additional benefits to completing upper secondary compared to lower secondary education in a middle-income country.We performed a longitudinal analysis of the Cape Area Panel Study, a survey of adolescents living in South Africa. We undertook causal modeling using structural marginal models to examine the association between level of education and various health outcomes, using inverse probability weighting to control for sex, age, ethnicity, home language, income, whether employed in past year, region of birth, maternal educational status, marital status, whether currently pregnant and cognitive ability. Educational attainment was defined as primary (grades 1-7, lower secondary (grades 8-9 or upper secondary (grades 10-12.Of 3,432 participants, 165 (4.8% had completed primary education, 646 (18.8% lower secondary and 2,621 (76.3% upper secondary. Compared to those completing lower secondary, males completing upper secondary education were less likely to have a health problem (OR 0.49; 95%CI 0.27-0.88; p = 0.02; describe their health as poor (0.52; 0.29-0.95; p = 0.03 or report that health interferes with daily life (0.54; 0.29-0.99; p = 0.047. Females were less likely to have been pregnant (0.45; 0.33-0.61; p<0.001 or pregnant under 18 (0.32; 0.22-0.46; p<0.001; and having had sex under 16 was also less likely (males 0.63; 0.44-0.91; p = 0.01; females 0.39; 0.26-0.58; p<0.001. Cigarette smoking was less likely (males 0.52; 0.38-0.70; p = <0.001; females 0.56; 0.41-0.76; p<0.001, as was taking illicit drugs in males (0.6; 0.38-0.96; p = 0.03. No associations were found between education and alcohol use, psychological distress, obesity, increased waist circumference or hypertension.Completing upper secondary education was associated with improved health outcomes compared with lower secondary

  5. Lecture Attendance, Study Time, and Academic Performance: A Panel Data Study

    Science.gov (United States)

    Andrietti, Vincenzo; Velasco, Carlos

    2015-01-01

    The authors analyze matched administrative survey data on economics students enrolled in two econometrics courses offered in consecutive terms at a major public university in Spain to assess the impact of lecture attendance and study time on academic performance. Using proxy variables in a cross-sectional regression setting, they find a positive…

  6. A Numerical Study on the Effect of Facesheet-Core Disbonds on the Buckling Load of Curved Honeycomb Sandwich Panels

    Science.gov (United States)

    Pineda, Evan J.; Myers, David E.; Bednarcyk, Brett A.; Krivanek, Thomas M.

    2015-01-01

    A numerical study on the effect of facesheet-core disbonds on the post-buckling response of curved honeycomb sandwich panels is presented herein. This work was conducted as part of the development of a damage tolerance approach for the next-generation Space Launch System heavy lift vehicle payload fairing. As such, the study utilized full-scale fairing barrel segments as the structure of interest. The panels were composed of carbon fiber reinforced polymer facesheets and aluminum honeycomb core. The panels were analyzed numerically using the finite element method. Facesheet and core nodes in a predetermined circular region were detached to simulate a disbond induced via low-speed impact between the outer mold line facesheet and honeycomb core. Surface-to-surface contact in the disbonded region was invoked to prevent interpenetration of the facesheet and core elements. The diameter of this disbonded region was varied and the effect of the size of the disbond on the post-buckling response was observed. A significant change in the slope of the edge load-deflection response was used to determine the onset of global buckling and corresponding buckling load.

  7. Building America Case Study: Trade-Friendly Retrofit Insulated Panels for Existing Buildings, Albany, New York

    Energy Technology Data Exchange (ETDEWEB)

    2016-03-01

    This project evaluated the effectiveness and affordability of integrating retrofit insulated panels into a re-siding project. The Partnership for Home Innovation (PHI) teamed with New York State Energy Research and Development Authority (NYSERDA), the Albany Housing Authority (AHA), and the New York State Weatherization Assistance Program (WAP) administered by Albany Community Action Partnership to demonstrate an energy retrofit and siding upgrade on a two-story, seven unit, multifamily building in Albany New York (CZ 5). The project focused on accomplishing three goals - doubling the existing wall thermal resistance (from approximately R-13 to a weighted average of R-27), reduction of building air leakage, and completion of the retrofit within a budget where the additional cost for upgrading wall's thermal resistance is equal to the cost of the standard re-siding effort (i.e., the total cost of the energy efficient re-siding scope of work is not more than double the cost of the standard re-siding effort). Lessons learned from the project strongly indicate that the retrofit panel technology can be installed using common installation practices and with minimal training. Other lessons learned include limitation on the use of standard air sealing materials during cold weather installations and the need to develop better installation guidance for trades working with the level of tolerances that may be present in the existing structure. This technology demonstration showed that exterior retrofit panels provide a viable and reasonable option for the siding trades to increase market opportunities and achieve synergistic benefits for aesthetic upgrades to a building's exterior.

  8. Physical activity levels and determinants of change in young adults: a longitudinal panel study

    Directory of Open Access Journals (Sweden)

    Zimmermann Erwin

    2010-01-01

    Full Text Available Abstract Background There is growing concern about physical inactivity in adolescents and young adults. Identifying determinants that are associated with low levels of physical activity and with changes in physical activity levels will help to develop specific prevention strategies. The present study describes the prevalence and potential determinants of physical activity behavior and behavior changes of young adults. The study is based on the Swiss Household Panel (SHP, a longitudinal study assessing social changes in a representative sample of Swiss households since 1999. Methods Data is collected yearly using computer-assisted telephone interviews. Information is obtained from each household member over 14 years of age. Participants between 14 and 24 years entering the SHP between 1999 and 2006 were included (N = 3,068. "Inactive" was defined as less than 1 day/week of at least 30 minutes of moderate physical activity, "no sport" as exercising less than once a week. Age, gender, nationality, linguistic region, household income, education, membership in a sport club, reading, and Internet use were included as potential determinants of physical activity behavior and behavior change. Results In both young men and young women, the prevalence of inactivity, "no sport", and non-membership in a sport club was increasing with age. Women were less active than men of the same age. From one wave to the following, 11.1% of young men and 12.1% of young women became active, and 11.9% of men and 13.7% of women became inactive, respectively (pooled data over all eight waves. Non-membership in a sport club was the strongest predictor for "no sport" (ORmen 6.7 [4.9-8.9]; ORwomen 8.1 [5.7-11.4], but also for being inactive (OR 4.6 [3.5-6.0]; 4.6 [3.3-6.4]. Leaving a sport club (OR 7.8 [4.4-14.0]; 11.9 [5.9-24.1] and remaining non-member (OR 7.8 [4.7-12.9]; 12.4 [6.4-24.1] were the strongest predictors of becoming "no sport". Effects for becoming inactive were

  9. APLIKASI REGRESI DATA PANEL DENGAN PENDEKATAN FIXED EFFECT MODEL (STUDI KASUS: PT PLN GIANYAR

    Directory of Open Access Journals (Sweden)

    NI PUTU ANIK MAS RATNASARI

    2014-01-01

    Full Text Available Panel data regression has three approaches. One of these approaches is Fixed Effect Model (FEM. FEM is common estimated using Least Square Dummy Variable. The use of dummy variable in FEM is based on assumption that slope coefficients are constant but intercept varies over individuals. One of application of FEM is to find out motivation of employees at PT PLN Gianyar for non-outsourcing and outsourcing employees based on existence, relatedness, and growth. This research yields the following two models: with 67% motivation non-outsourcing employees represented by existenceand73% motivation non-outsourcing employees represented by existence and growth.

  10. Technology Solutions for Existing Homes Case Study: Trade-Friendly Retrofit Insulated Panels for Existing Buildings

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-03-01

    For this project with the U.S. Department of Energy Building America team Home Innovation Research Labs, the retrofit insulated panels relied on an enhanced expanded polystyrene (EPS) for thermal resistance of R-4.5/inch, which is an improvement of 10% over conventional (white-colored) EPS. EPS, measured by its life cycle, is an alternative to commonly used extruded polystyrene and spray polyurethane foam. It is a closed-cell product made up of 90% air, and it requires about 85% fewer petroleum products for processing than other rigid foams.

  11. The genetic and environmental foundations of political, psychological, social, and economic behaviors: a panel study of twins and families.

    Science.gov (United States)

    Hatemi, Peter K; Smith, Kevin; Alford, John R; Martin, Nicholas G; Hibbing, John R

    2015-06-01

    Here we introduce the Genetic and Environmental Foundations of Political and Economic Behaviors: A Panel Study of Twins and Families (PIs Alford, Hatemi, Hibbing, Martin, and Smith). This study was designed to explore the genetic and environmental influences on social, economic, and political behaviors and attitudes. It involves identifying the psychological mechanisms that operate on these traits, the heritability of complex economic and political traits under varying conditions, and specific genetic correlates of attitudes and behaviors. In addition to describing the study, we conduct novel analyses on the data, estimating the heritability of two traits so far unexplored in the extant literature: Machiavellianism and Baron-Cohen's Empathizing Quotient.

  12. Proposed minimal panel of antibodies for cost-effectiveness and accuracy in acute leukemias immunophenotyping: Prospective study at a tertiary care center.

    Science.gov (United States)

    Singh, Neha; Pati, Hara Prasad P; Tyagi, Seema; Deka, Roopam; Sharma, Rahul; Saxena, Renu

    2016-07-01

    Flowcytometry has an essential role in the diagnosis and classification of acute leukemias. However, there exists a great degree of inter-laboratory variability on issues like panel selection, antibody combinations, gating strategies, fluorochromes, and clonal selection. The primary aim of this study was to derive a minimal panel of antibodies and evaluate its diagnostic usefulness in acute leukemias by flowcytometry by using the detailed immune-phenotype of different lineage-specific or non-specific markers. This prospective observational study involved 400 newly diagnosed cases of acute leukemias. Bone marrow aspirate samples were subjected to morphological evaluation, cytogenetics and flow cytometric immunophenotyping. A minimal panel of eight antibodies comprising of CD45/CD34/CD19/MPO/cytoCD3/CD64/CD117/CD79a was derived by applying different permutations and combinations with a diagnostic yield of 97.5%. The minimal panel was further validated by testing in an independent cohort of patients with similar demographic characteristics, where it showed a high diagnostic yield of 98% in comparison with the screening panels proposed by other recently published studies. It may be concluded that the diagnostic performance of the eight antibody panel is better than most other panels used across the different laboratories in terms of yield, number of antibodies used and the scientific approach used to derive and validate the results and so henceforth may be applied in any setting with limited resources for better diagnostic accuracy.

  13. What is case management in palliative care? An expert panel study

    Directory of Open Access Journals (Sweden)

    van der Plas Annicka G M

    2012-06-01

    Full Text Available Abstract Background Case management is a heterogeneous concept of care that consists of assessment, planning, implementing, coordinating, monitoring, and evaluating the options and services required to meet the client's health and service needs. This paper describes the result of an expert panel procedure to gain insight into the aims and characteristics of case management in palliative care in the Netherlands. Methods A modified version of the RAND®/University of California at Los Angeles (UCLA appropriateness method was used to formulate and rate a list of aims and characteristics of case management in palliative care. A total of 76 health care professionals, researchers and policy makers were invited to join the expert panel, of which 61% participated in at least one round. Results Nine out of ten aims of case management were met with agreement. The most important areas of disagreement with regard to characteristics of case management were hands-on nursing care by the case manager, target group of case management, performance of other tasks besides case management and accessibility of the case manager. Conclusions Although aims are agreed upon, case management in palliative care shows a high level of variability in implementation choices. Case management should aim at maintaining continuity of care to ensure that patients and those close to them experience care as personalised, coherent and consistent.

  14. MO-E-BRB-00: PANEL DISCUSSION: SBRT/SRS Case Studies - Lung

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-06-15

    In this interactive session, lung SBRT patient cases will be presented to highlight real-world considerations for ensuring safe and accurate treatment delivery. An expert panel of speakers will discuss challenges specific to lung SBRT including patient selection, patient immobilization techniques, 4D CT simulation and respiratory motion management, target delineation for treatment planning, online treatment alignment, and established prescription regimens and OAR dose limits. Practical examples of cases, including the patient flow thought the clinical process are presented and audience participation will be encouraged. This panel session is designed to provide case demonstration and review for lung SBRT in terms of (1) clinical appropriateness in patient selection, (2) strategies for simulation, including 4D and respiratory motion management, and (3) applying multi imaging modality (4D CT imaging, MRI, PET) for tumor volume delineation and motion extent, and (4) image guidance in treatment delivery. Learning Objectives: Understand the established requirements for patient selection in lung SBRT Become familiar with the various immobilization strategies for lung SBRT, including technology for respiratory motion management Understand the benefits and pitfalls of applying multi imaging modality (4D CT imaging, MRI, PET) for tumor volume delineation and motion extent determination for lung SBRT Understand established prescription regimes and OAR dose limits.

  15. Transportation and socioeconomic impacts of bypasses on communities : an integrated synthesis of panel data, multilevel, and spatial econometric models with case studies.

    Science.gov (United States)

    2011-09-21

    Title: Transportation and Socioeconomic Impacts of Bypasses on Communities: An Integrated Synthesis of Panel Data, Multilevel, and Spatial Econometric Models with Case Studies. The title used at the start of this project was Transportation and Soc...

  16. A Multidisciplinary Approach to a Seven Year-Old Patient with Incontinentia Pigmenti: A Case Report and Five-Year Follow Up

    Directory of Open Access Journals (Sweden)

    Rezvan Rafatjou

    2016-11-01

    Full Text Available Incontinentia pigmenti is a rare inherited disorder involving abnormalities of the skin, hair, eyes, musculoskeletal system, central nervous system, and the teeth. Dental abnormalities are the most common manifestations of this disorder. The purpose of this case report was to present the clinical and radiological findings of a seven-year-old girl as well as the results of her five-year follow up. The patient showed faded linear pigmented macular lesions on the trunk and on upper and lower limbs. Dental examination was notable for conical and peg-shaped anterior teeth as well as delayed eruption of primary and permanent teeth. In addition to conservative treatments, prosthetic treatments such as interim removable partial dentures were indicated for the patient.Keywords: Incontinentia Pigmenti; Dental Prosthesis; Genetic Diseases, Inborn 

  17. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

    Directory of Open Access Journals (Sweden)

    Paul S de Vries

    Full Text Available An increasing number of genome-wide association (GWA studies are now using the higher resolution 1000 Genomes Project reference panel (1000G for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associated loci when compared to HapMap imputation. In order to assess the improvement of 1000G over HapMap imputation in identifying associated loci, we compared the results of GWA studies of circulating fibrinogen based on the two reference panels. Using both HapMap and 1000G imputation we performed a meta-analysis of 22 studies comprising the same 91,953 individuals. We identified six additional signals using 1000G imputation, while 29 loci were associated using both HapMap and 1000G imputation. One locus identified using HapMap imputation was not significant using 1000G imputation. The genome-wide significance threshold of 5×10-8 is based on the number of independent statistical tests using HapMap imputation, and 1000G imputation may lead to further independent tests that should be corrected for. When using a stricter Bonferroni correction for the 1000G GWA study (P-value < 2.5×10-8, the number of loci significant only using HapMap imputation increased to 4 while the number of loci significant only using 1000G decreased to 5. In conclusion, 1000G imputation enabled the identification of 20% more loci than HapMap imputation, although the advantage of 1000G imputation became less clear when a stricter Bonferroni correction was used. More generally, our results provide insights that are applicable to the implementation of other dense reference panels that are under development.

  18. Modifiable health risks and illness absence from work: evidence from the panel study of income dynamics.

    Science.gov (United States)

    Gifford, Brian

    2013-03-01

    Modifiable health risks such as smoking, exercise, and body weight have been linked to illness absence from work. This suggests that employers could improve their productivity if their workers adopted healthier lifestyles, but methodological concerns regarding selection bias and omitted variables remain. We use a first-difference model of changes in health behaviors and illness- and family-related absence from work among a nationally representative, longitudinal panel of employed individuals. Workers who lost weight or increased their frequency of light exercise also saw their illness absences decrease over a 2-year period. Some, but not all, of the relationship is mediated by the change in health status. No such decrease was observed for family-related absences. The findings are consistent with the proposition that both employers and employees could benefit from efforts to support better health habits.

  19. Determinants of Multilateral Official Development Assistance: Evidence from a Panel Study of Countries in Sub-Saharan Africa

    OpenAIRE

    Hlavac, Marek

    2007-01-01

    Countries in sub-Saharan Africa are some of the poorest and least developed in the world, with deplorable health and education levels. One way intended to promote better living standards in this region has been through development aid. This study examines the determinants of multilateral aid inflows to sub-Saharan Africa to determine whether it is directed to the least developed countries. I use panel data about 22 countries in sub-Saharan Africa from the 1995-2004 period to estimate a regres...

  20. Panel discussion

    Energy Technology Data Exchange (ETDEWEB)

    No Author Given

    1975-01-01

    Panel discussion: summation and future projections. Introductory remarks by panelists followed by questions and comments from the floor. Panelists: Dr. Joseph Barnea (former director of Resources and Transport for the United Nations; energy consultant to the United Nations Institute for Training and Research (UNITAR)); the Honorable Clyde F. Bel, Jr. (member of the Louisiana House of Representatives representing District 90 and New Orleans); Dr. David Lombard (acting chief of the Advanced Systems Branch of the Division of Geothermal Energy Research and Technology, Energy Research and Development Administration (ERDA)); Fred C. Repper (vice-president of Central Power and Light Company in Corpus Christi, Texas); Dr. Hans Suter (environmental consultant in Corpus Christi, Texas; environmental columnist for the Corpus Christi Caller Times). Session chairman: Herbert Woodson.

  1. Clinical management and associated costs for moderate and severe Alzheimer's disease in urban China: a Delphi panel study.

    Science.gov (United States)

    Yu, Xin; Chen, Shengdi; Chen, Xiaochun; Jia, Jianjun; Li, Chunhou; Liu, Cong; Toumi, Mondher; Milea, Dominique

    2015-01-01

    Healthcare resource utilisation for Alzheimer's disease (AD) in China is not well understood. This Delphi panel study aimed to describe the clinical management pathways for moderate and severe AD patients in urban China and to define the amount and cost of healthcare resources used. A panel of 11 experts was recruited from urban China to participate in two rounds of preparatory interviews. In the first round, 9 physicians specialised in dementia gave a qualitative description of the clinical management of AD patients. In the second round, 2 hospital administrators were asked about the cost of AD management and care. Results from the interviews were discussed by the experts in a Delphi panel meeting, where consensus was reached on quantitative aspects of AD management, including the rate of healthcare resource utilisation, the respective unit costs and caregiving time. Interviewees reported that mild AD is under-recognised in China; most patients are diagnosed with moderate to severe AD. Loss of independence and agitation/aggression are the main drivers for healthcare resource utilisation and contribute to a heavier caregiver burden. It was estimated that 70 % moderate AD patients are independent/non-aggressive at the time of diagnosis, 15 % are independent/aggressive, 10 % are dependent/non-aggressive, and 5 % are dependent/aggressive. Dependent/aggressive AD patients are more likely to be hospitalised (70-90 %) than accepted in a nursing home (0-20 %), while the opposite is true for dependent/non-aggressive patients (5-35 % for hospitalisation vs. 80 % for nursing home). Independent AD patients require 1-3 hours/day of caregiver time, while dependent patients can require up to 12-15 hours/day. Experts agreed that AD complicates the management of age-related comorbidities, found in 70-80 % of all AD patients, increasing the frequency and cost of hospitalisation. The Delphi panel approach was an efficient method of gathering data about the amount of

  2. Panel 4: Report of the Microbiology Panel.

    Science.gov (United States)

    Barenkamp, Stephen J; Chonmaitree, Tasnee; Hakansson, Anders P; Heikkinen, Terho; King, Samantha; Nokso-Koivisto, Johanna; Novotny, Laura A; Patel, Janak A; Pettigrew, Melinda; Swords, W Edward

    2017-04-01

    Objective To perform a comprehensive review of the literature from July 2011 until June 2015 on the virology and bacteriology of otitis media in children. Data Sources PubMed database of the National Library of Medicine. Review Methods Two subpanels comprising experts in the virology and bacteriology of otitis media were created. Each panel reviewed the relevant literature in the fields of virology and bacteriology and generated draft reviews. These initial reviews were distributed to all panel members prior to meeting together at the Post-symposium Research Conference of the 18th International Symposium on Recent Advances in Otitis Media, National Harbor, Maryland, in June 2015. A final draft was created, circulated, and approved by all panel members. Conclusions Excellent progress has been made in the past 4 years in advancing our understanding of the microbiology of otitis media. Numerous advances were made in basic laboratory studies, in animal models of otitis media, in better understanding the epidemiology of disease, and in clinical practice. Implications for Practice (1) Many viruses cause acute otitis media without bacterial coinfection, and such cases do not require antibiotic treatment. (2) When respiratory syncytial virus, metapneumovirus, and influenza virus peak in the community, practitioners can expect to see an increase in clinical otitis media cases. (3) Biomarkers that predict which children with upper respiratory tract infections will develop otitis media may be available in the future. (4) Compounds that target newly identified bacterial virulence determinants may be available as future treatment options for children with otitis media.

  3. Heat exchanger panel

    Science.gov (United States)

    Warburton, Robert E. (Inventor); Cuva, William J. (Inventor)

    2005-01-01

    The present invention relates to a heat exchanger panel which has broad utility in high temperature environments. The heat exchanger panel has a first panel, a second panel, and at least one fluid containment device positioned intermediate the first and second panels. At least one of the first panel and the second panel have at least one feature on an interior surface to accommodate the at least one fluid containment device. In a preferred embodiment, each of the first and second panels is formed from a high conductivity, high temperature composite material. Also, in a preferred embodiment, the first and second panels are joined together by one or more composite fasteners.

  4. Longitudinal patterns of problematic computer game use among adolescents and adults--a 2-year panel study.

    Science.gov (United States)

    Scharkow, Michael; Festl, Ruth; Quandt, Thorsten

    2014-11-01

    To investigate the longitudinal patterns (stability and change) of problematic computer game use and its interdependencies with psychosocial wellbeing in different age groups. Three-wave, annual panel study using computer-assisted telephone surveys. Germany. A total of 112 adolescents aged between 14 and 18 years, 363 younger adults between 19-39 years and 427 adults aged 40 years and older (overall n = 902). Problematic game use was measured with the Gaming Addiction Short Scale (GAS), which covers seven criteria including salience, withdrawal and conflict. Additionally, gaming behaviour and psychosocial wellbeing (social capital and support, life satisfaction and success) were measured in all three panel waves. The generally low GAS scores were very stable in yearly intervals [average autocorrelation across waves and age groups: r = 0.74, confidence interval (CI) = 0.71, 0.77]. Only nine respondents (1%, CI = 0.5, 1.9) consistently exhibited symptoms of problematic game use across all waves, while no respondent could be classified consistently as being addicted according to the GAS criteria. Changes in problematic gaming were not related consistently to changes in psychosocial wellbeing, although some cross-lagged effects were statistically significant in younger and older adult groups. Within a 2-year time-frame, problematic use of computer games appears to be a less stable behaviour than reported previously and not related systematically to negative changes in the gamers' lives. © 2014 Society for the Study of Addiction.

  5. Advanced solar panel designs

    Science.gov (United States)

    Ralph, E. L.; Linder, E.

    1995-01-01

    This paper describes solar cell panel designs that utilize new hgih efficiency solar cells along with lightweight rigid panel technology. The resulting designs push the W/kg and W/sq m parameters to new high levels. These new designs are well suited to meet the demand for higher performance small satellites. This paper reports on progress made on two SBIR Phase 1 contracts. One panel design involved the use of large area (5.5 cm x 6.5 cm) GaAs/Ge solar cells of 19% efficiency combined with a lightweight rigid graphite fiber epoxy isogrid substrate configuration. A coupon (38 cm x 38 cm) was fabricated and tested which demonstrated an array specific power level of 60 W/kg with a potential of reaching 80 W/kg. The second panel design involved the use of newly developed high efficiency (22%) dual junction GaInP2/GaAs/Ge solar cells combined with an advanced lightweight rigid substrate using aluminum honeycomb core with high strength graphite fiber mesh facesheets. A coupon (38 cm x 38 cm) was fabricated and tested which demonstrated an array specific power of 105 W/kg and 230 W/sq m. This paper will address the construction details of the panels and an a analysis of the component weights. A strawman array design suitable for a typical small-sat mission is described for each of the two panel design technologies being studied. Benefits in respect to weight reduction, area reduction, and system cost reduction are analyzed and compared to conventional arrays.

  6. Flat panel CT following stapes prosthesis insertion: an experimental and clinical study

    Energy Technology Data Exchange (ETDEWEB)

    Zaoui, K. [University-Hospital Heidelberg, Ludwig-Karls-University Heidelberg, Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg (Germany); Kromeier, J. [St.-Josefs-Hospital, RkK, Department of Radiology, Freiburg (Germany); Neudert, M.; Zahnert, T. [University-Hospital Dresden, Technical-University Dresden, Department of Otorhinolaryngology, Head and Neck Surgery, Dresden (Germany); Boedeker, C.C.; Laszig, R.; Offergeld, C. [University-Hospital Freiburg, Albert-Ludwigs-University Freiburg, Department of Otorhinolaryngology, Head and Neck Surgery, Freiburg (Germany)

    2012-04-15

    Anatomical information of the middle and inner ear is becoming increasingly important in post-operative evaluation especially after stapesplasty with unsuccessful improvement of the air-bone gap (ABG). So far computed tomography (CT) has been the first choice for detection of reasons for recurrent hearing loss. CT has the disadvantage of metal-induced artefacts after insertion of middle ear implants and of a relatively high irradiation dose. Flat panel CT (fpCT) was performed in three temporal bone specimen after experimental insertion of different stapes prostheses, aiming to validate the accuracy of fpCT of the middle and inner ear. Additionally, 28 consecutive patients, supplied with different stapes prostheses underwent post-operative fpCT to compare the pre- and post-operative hearing results with the determined prosthesis position in the middle and inner ear. In all cases, fpCT showed a statistically significant correlation between hearing improvement and prosthesis position. This technique provided detailed post-operative information of the implant position in patients and temporal bone specimen. The new imaging technique of fpCT allows the immediate and almost artefact-free evaluation of surgical results following stapesplasty. Further benefits are a lower irradiation dose and higher isovolumetric resolution compared with standard CT. (orig.)

  7. TU-A-BRB-00: PANEL DISCUSSION: SBRT/SRS Case Studies - Brain and Spine

    International Nuclear Information System (INIS)

    2016-01-01

    Brain stereotactic radiosurgery (SRS) and spine stereotactic body radiation therapy (SBRT) are commonly treated by a multidisciplinary team of neurosurgeons, radiation oncologists, and medical physicists. However the treatment objectives, constraints, and technical considerations involved can be quite different between the two techniques. In this interactive session an expert panel of speakers will present clinical brain SRS and spine SBRT cases in order to demonstrate real-world considerations for ensuring safe and accurate treatment delivery and to highlight the significant differences in approach for each treatment site. The session will include discussion of topic such as clinical indications, immobilization, target definition, normal tissue tolerance limits, and beam arrangements. Learning Objectives: Understand the differences in indications and dose/fractionation strategies for intracranial SRS and spine SBRT. Describe the different treatment modalities which can be used to deliver intracranial SRS and spine SBRT. Cite the major differences in treatment setup and delivery principles between intracranial and spine treatments. Identify key critical structures and clinical dosimetric tolerance levels for spine SBRT and intracranial SRS. Understand areas of ongoing work to standardize intracranial SRS and spine SBRT procedures. Schlesinger: Research support: Elekta Instruments, AB; D. Schlesinger, Elekta Instruments, AB - research support; B. Winey, No relevant external funding for this subject.

  8. Selection of population controls for a Salmonella case-control study in the UK using a market research panel and web-survey provides time and resource savings.

    Science.gov (United States)

    Mook, P; Kanagarajah, S; Maguire, H; Adak, G K; Dabrera, G; Waldram, A; Freeman, R; Charlett, A; Oliver, I

    2016-04-01

    Timely recruitment of population controls in infectious disease outbreak investigations is challenging. We evaluated the timeliness and cost of using a market research panel as a sampling frame for recruiting controls in a case-control study during an outbreak of Salmonella Mikawasima in the UK in 2013. We deployed a web-survey by email to targeted members of a market research panel (panel controls) in parallel to the outbreak control team interviewing randomly selected public health staff by telephone and completing paper-based questionnaires (staff controls). Recruitment and completion of exposure history web-surveys for panel controls (n = 123) took 14 h compared to 15 days for staff controls (n = 82). The average staff-time cost per questionnaire for staff controls was £13·13 compared to an invoiced cost of £3·60 per panel control. Differences in the distribution of some exposures existed between these control groups but case-control studies using each group found that illness was associated with consumption of chicken outside of the home and chicken from local butchers. Recruiting market research panel controls offers time and resource savings. More rapid investigations would enable more prompt implementation of control measures. We recommend that this method of recruiting controls is considered in future investigations and assessed further to better understand strengths and limitations.

  9. Dose-Response Relation Between Work Hours and Cardiovascular Disease Risk: Findings From the Panel Study of Income Dynamics.

    Science.gov (United States)

    Conway, Sadie H; Pompeii, Lisa A; Roberts, Robert E; Follis, Jack L; Gimeno, David

    2016-03-01

    The aim of this study was to examine the presence of a dose-response relationship between work hours and incident cardiovascular disease (CVD) in a representative sample of U.S. workers. A retrospective cohort study of 1926 individuals from the Panel Study of Income Dynamics (1986 to 2011) employed for at least 10 years. Restricted cubic spline regression was used to estimate the dose-response relationship of work hours with CVD. A dose-response relationship was observed in which an average workweek of 46 hours or more for at least 10 years was associated with an increased risk of CVD. Compared with working 45 hours per week, working an additional 10 hours per week or more for at least 10 years increased CVD risk by at least 16%. Working more than 45 work hours per week for at least 10 years may be an independent risk factor for CVD.

  10. Economic situation and occupational accidents in Poland: 2002-2014 panel data regional study.

    Science.gov (United States)

    Łyszczarz, Błażej; Nojszewska, Ewelina

    2018-01-07

    Occupational accidents constitute a substantial health and economic burden for societies around the world and a variety of factors determine the frequency of accidents at work. The aim of this paper is to investigate the relationship between the economic situation and the rate of occupational accidents in Poland. The analysis comprised data for 66 Polish sub-regions taken from the Central Statistical Office's Local Data Bank. The regression analysis with panel data for period 2002-2014 was applied to identify the relationships involved. Four measures of accidents were used: the rates of total occupational accidents, accidents among men and women separately as well as days of incapacity to work due to accidents at work per employee. Four alternative measures assessed the economic situation: gross domestic product (GDP) per capita, average remuneration, the unemployment rate and number of dwelling permits. The confounding variables included were: employment in hazardous conditions and the size of enterprises. The results of the regression estimates show that the number of occupational accidents in Poland exhibits procyclical behavior, which means that more accidents are observed during the times of economic expansion. Stronger relationships were observed in the equations explaining men's accident rates as well as total rates. A weaker and not always statistically significant impact of economic situation was identified for women's accident rates and days of incapacity to work. The results have important implications for occupational health and safety actions. In the periods of higher work intensity employers should focus on appropriate training and supervision of inexperienced workers as well as on ensuring enough time for already experienced employees to recuperate. In terms of public health actions, policy makers should focus on scrutinizing working conditions, educating employers and counteracting possible discrimination of injured employees. Int J Occup Med

  11. Socioeconomic inequalities in health in the context of multimorbidity: A Korean panel study.

    Directory of Open Access Journals (Sweden)

    Myung Ki

    Full Text Available Socioeconomic inequalities in health are commonly known to decrease at late age. Yet, it remains unclear whether socioeconomic inequalities in health at late age appear in relation to multimorbidity, particularly in Korea where social support remains unsatisfactory for older people. Using three waves of Korea Health Panel, data of 19,942 observations with repeated measure were constructed to ensure a temporal sequence between three socioeconomic measures (i.e., poverty, employment status, and education and multimorbidity with a t to t+1 year transition. A multilevel multinomial model was applied to quantify the socioeconomic impact across different age, diseases and disease groups, both separately and in combination. There were associations between socioeconomic position (SEP and multimorbidity, and increasing trends of socioeconomic inequalities not only with greater number of morbidity but also with age. The latter result was only observed with employment status through mid-to-early old age; i.e., between the 40s (odds ratio (OR = 2.45, 95% confidence interval (CI:1.08-5.57 and 70s (OR = 3.48, 95%CI: 1.24-9.74. The patterns of socioeconomic inequalities in multimorbidity varied for particular pairs of diseases and were stronger in the disease pairs co-occurring with mental and cardiovascular diseases but weaker in the disease pairs co-occurring with cancer. Accumulation of adversity tended to intensify with increase in number of diseases and older age, though this finding was not consistently supported. The labour market should be encouraged to actively participate in actions to promote healthy aging needs to be complemented by the provision of more generous and universal income support to the elderly in Korea.

  12. Classification of acute decompensated heart failure: an automated algorithm compared with a physician reviewer panel: the Atherosclerosis Risk in Communities study.

    Science.gov (United States)

    Loehr, Laura R; Agarwal, Sunil K; Baggett, Chris; Wruck, Lisa M; Chang, Patricia P; Solomon, Scott D; Shahar, Eyal; Ni, Hanyu; Rosamond, Wayne D; Heiss, Gerardo

    2013-07-01

    An algorithm to classify heart failure (HF) end points inclusive of contemporary measures of biomarkers and echocardiography was recently proposed by an international expert panel. Our objective was to assess agreement of HF classification by this contemporaneous algorithm with that by a standardized physician reviewer panel, when applied to data abstracted from community-based hospital records. During 2005-2007, all hospitalizations were identified from 4 US communities under surveillance as part of the Atherosclerosis Risk in Communities (ARIC) study. Potential HF hospitalizations were sampled by International Classification of Diseases discharge codes and demographics from men and women aged ≥ 55 years. The HF classification algorithm was automated and applied to 2729 (n=13854 weighted hospitalizations) hospitalizations in which either brain natriuretic peptide measures or ejection fraction were documented (mean age, 75 years). There were 1403 (54%; n=7534 weighted) events classified as acute decompensated HF by the automated algorithm, and 1748 (68%; n=9276 weighted) such events by the ARIC reviewer panel. The chance-corrected agreement between acute decompensated HF by physician reviewer panel and the automated algorithm was moderate (κ=0.39). Sensitivity and specificity of the automated algorithm with ARIC reviewer panel as the referent standard were 0.68 (95% confidence interval, 0.67-0.69) and 0.75 (95% confidence interval, 0.74-0.76), respectively. Although the automated classification improved efficiency and decreased costs, its accuracy in classifying HF hospitalizations was modest compared with a standardized physician reviewer panel.

  13. Seven-year time trends in energy balance-related behaviours according to educational level and ethnic background among 14-year-old adolescents.

    Science.gov (United States)

    Meijerink, Frederika J; van Vuuren, C Leontine; Wijnhoven, Hanneke A H; van Eijsden, Manon

    2016-04-01

    To assess seven-year time trends in energy balance-related behaviours in 14-year-old adolescents living in an urban area and to examine the influence of educational level and ethnicity on these time trends. Second grade students (mean age 13·6 years) filled in questionnaires about the energy balance-related behaviours of breakfast consumption, fruit and vegetable consumption, physical activity and screen-time behaviour from school years 2006-2007 to 2012-2013. Energy balance-related behaviours were dichotomized and logistic regression analyses were used to examine time trends in healthy energy balance-related behaviours, including interaction terms for educational level and ethnicity. Secondary schools in Amsterdam, the Netherlands. Per school year, 2185-3331 children participated. The total sample included 19 244 students of Dutch, Surinamese, Turkish and Moroccan ethnic background. A significant linear increase was found for positive screen-time behaviour (Time trends in screen time were significantly different across educational levels (P-interaction=0·002) and ethnic backgrounds (Ptime trends in daily fruit consumption (P=0·017 and P=0·018, respectively) and, for ethnicity, trends in daily vegetable consumption (Ptime behaviour is a positive finding. However, discouraging screen time and promoting other healthy behaviours, more specifically daily fruit and vegetable consumption, remain important particularly among adolescents enrolled in pre-vocational education and of non-Dutch ethnic background.

  14. Granulomatous slack skin - seven years follow-up of a case with features of "parapsoriasis en plaques", muscle involvement, granulomatous vasculitis, and necrobiotic changes.

    Science.gov (United States)

    ChiriŢă, Aurel Doru; Mărgăritescu, Irina

    2016-01-01

    Granulomatous slack skin (GSS) represents an extremely rare variant of mycosis fungoides with only 70 cases reported in the literature to date. It is characterized clinically by the occurrence of bulky, pendulous skinfolds, usually located in flexural areas and histologically by an infiltrate composed of small neoplastic T-lymphocytes joined by granulomatous inflammation with scattered multinucleated giant cells containing nuclei arranged in a wreath-like fashion. Since its first description, very rare cases of GSS with muscle involvement, large vessels involvement, or necrobiotic changes have been reported. We present an extraordinary case of GSS with all these unusual features developing in the lesions of the same patient. The long follow-up of seven years allowed us to document the evolution of each lesion. Some lesions appeared and evolved in a manner very reminiscent of those of "parapsoriasis en plaques", others were classical GSS lesions, and still others developed large ulcerated lesions. These ulcerated lesions consistently failed to respond to conventional wound therapy, skin directed therapy [retinoids + psoralen combined with ultraviolet A (PUVA)-therapy], and interferon-alpha therapy. Remarkably, the ulcers completely healed when systemic corticosteroids were added. We hence postulate that the ulcers appeared because of large vessel vasculitis rather than tumoral direct destruction.

  15. Volcano-like intermittent bleeding activity for seven years from an arterio-enteric fistula on a kidney graft site after pancreas-kidney transplantation: a case report

    Directory of Open Access Journals (Sweden)

    Schölmerich Jürgen

    2010-11-01

    Full Text Available Abstract Introduction We report the first case of a patient who underwent simultaneous kidney and pancreas transplantation and who then suffered from repeated episodes of severe gastrointestinal bleeding over a period of seven years. Locating the site of gastrointestinal bleeding is a challenging task. This case illustrates that detection of an arterio-enteric fistula can be very difficult, especially in technically-challenging situations such as cases of severe intra-abdominal adhesions. It is important to consider the possibility of arterio-enteric fistulas in cases of intermittent bleeding episodes, especially in transplant patients. Case presentation A 40-year-old Caucasian man received a combined pancreas-kidney transplantation as a result of complications from diabetes mellitus type I. Thereafter, he suffered from intermittent clinically-relevant episodes of gastrointestinal bleeding. Repeat endoscopic, surgical, scintigraphic, and angiographic investigations during his episodes of acute bleeding could not locate the bleeding site. He finally died in hemorrhagic shock due to arterio-enteric bleeding at the kidney graft site, which was diagnosed post-mortem. Conclusions In accordance with the literature, we suggest considering the removal of any rejected transplant organs in situations where arterio-enteric fistulas seem likely but cannot be excluded by repeat conventional or computed tomography-angiographic methods. Arterio-enteric fistulas may intermittently bleed over many years.

  16. Uses of Activation Analysis in Studies of Mineral Element Metabolism in Man. Papers Given at a Panel Meeting

    International Nuclear Information System (INIS)

    1970-01-01

    In June, 1968, the International Atomic Energy Agency held a panel meeting in Teheran, Iran, to discuss some of the uses of activation analysis in studies of mineral element metabolism in man. The aims of the meeting were to identify and draw attention to specific medical problems to which activation analysis could be fruitfully applied, to review the capabilities of the technique itself, and to recommend specific action which the Agency might take to support further work in this field. The scientific papers presented at the meeting have been gathered together in this report, and it is hoped that their publication will be of interest to all concerned with mineral element metabolism in man, whether studied by activation analysis or by other methods

  17. Examining the Relationship Between Productivity Loss Trajectories and Work Disability Outcomes Using the Panel Study of Income Dynamics.

    Science.gov (United States)

    Besen, Elyssa; Pransky, Glenn

    2015-08-01

    To identify trajectories of productivity loss and examine the relationship between the trajectories and work disability outcomes. Latent class growth analysis of productivity loss was estimated for the ages of 25 to 44 years in the Panel Study of Income Dynamics (N = 4960). Differences among the trajectories for work disability outcomes for the ages of 25 to 64 years were estimated using logistic regression and analysis of variance. A five-group trajectory model was identified with a no-risk, low-risk, high-risk, early-onset increasing risk, and late-onset increasing risk group. The likelihood of ever experiencing permanent disability or receiving Social Security Disability Insurance between the ages of 25 and 64 years differed across the trajectories with the early-onset and high-risk groups having the greatest likelihood and the no-risk trajectory having the lowest likelihood of work disability. Productivity loss trajectories are highly related to work disability outcomes.

  18. Only when the societal impact potential is high? A panel study of the relationship between public service motivation and performance

    DEFF Research Database (Denmark)

    Loon, Nina van; Kjeldsen, Anne Mette; Andersen, Lotte Bøgh

    Does the performance of public organizations benefit from high public service motivation (PSM) under all circumstances? This article studies whether the societal impact potential (SIP) – the degree to which the job provides opportunities to contribute to society of the job –moderates...... the relationship between PSM and self-perceived performance, first on the individual level, and second on an organizational level. By shifting to the organizational level we are able to provide a test over time. Using organizational panel data from 2010 and 2012 on approximately 13.000 public employees, we...... (organizational level) or even no relationship (individual level) when SIP is low. This is an important insight for organizations that aim to enhance their performance through PSM as it shows that individual motives only contribute to performance when they are accounted for in the design of the work....

  19. A panel study on patients with dominant cerebellar ataxia highlights the frequency of channelopathies.

    Science.gov (United States)

    Coutelier, Marie; Coarelli, Giulia; Monin, Marie-Lorraine; Konop, Juliette; Davoine, Claire-Sophie; Tesson, Christelle; Valter, Rémi; Anheim, Mathieu; Behin, Anthony; Castelnovo, Giovanni; Charles, Perrine; David, Albert; Ewenczyk, Claire; Fradin, Mélanie; Goizet, Cyril; Hannequin, Didier; Labauge, Pierre; Riant, Florence; Sarda, Pierre; Sznajer, Yves; Tison, François; Ullmann, Urielle; Van Maldergem, Lionel; Mochel, Fanny; Brice, Alexis; Stevanin, Giovanni; Durr, Alexandra

    2017-06-01

    Autosomal dominant cerebellar ataxias have a marked heterogeneous genetic background, with mutations in 34 genes identified so far. This large amount of implicated genes accounts for heterogeneous clinical presentations, making genotype-phenotype correlations a major challenge in the field. While polyglutamine ataxias, linked to CAG repeat expansions in genes such as ATXN1, ATXN2, ATXN3, ATXN7, CACNA1A and TBP, have been extensively characterized in large cohorts, there is a need for comprehensive assessment of frequency and phenotype of more 'conventional' ataxias. After exclusion of CAG/polyglutamine expansions in spinocerebellar ataxia genes in 412 index cases with dominantly inherited cerebellar ataxias, we aimed to establish the relative frequencies of mutations in other genes, with an approach combining panel sequencing and TaqMan® polymerase chain reaction assay. We found relevant genetic variants in 59 patients (14.3%). The most frequently mutated were channel genes [CACNA1A (n = 16), KCND3 (n = 4), KCNC3 (n = 2) and KCNA1 (n = 2)]. Deletions in ITPR1 (n = 11) were followed by biallelic variants in SPG7 (n = 9). Variants in AFG3L2 (n = 7) came next in frequency, and variants were rarely found in STBN2 (n = 2), ELOVL5, FGF14, STUB1 and TTBK2 (n = 1 each). Interestingly, possible risk factor variants were detected in SPG7 and POLG. Clinical comparisons showed that ataxias due to channelopathies had a significantly earlier age at onset with an average of 24.6 years, versus 40.9 years for polyglutamine expansion spinocerebellar ataxias and 37.8 years for SPG7-related forms (P = 0.001). In contrast, disease duration was significantly longer in the former (20.5 years versus 9.3 and 13.7, P=0.001), though for similar functional stages, indicating slower progression of the disease. Of interest, intellectual deficiency was more frequent in channel spinocerebellar ataxias, while cognitive impairment in adulthood was similar among the three groups. Similar

  20. Drama to promote social and personal well-being in six- and seven-year-olds with communication difficulties: the Speech Bubbles project.

    Science.gov (United States)

    Barnes, Jonathan

    2014-03-01

    This paper focuses on an innovative intersection between education, health and arts. Taking a broad definition of health it examines some social and psychological well-being impacts of extended collaborations between a theatre company and children with communication difficulties. It seeks to test aspects of Fredrickson's(1) broaden-and-build theory of positive emotions in a primary school curriculum context. The researcher participated in a project called Speech Bubbles. The programme was devised by theatre practitioners and aimed at six- and seven-year-olds with difficulties in speech, language and communication. Sessions were observed, videoed and analysed for levels of child well-being using an established scale. In addition, responses regarding perceived improvements in speech, language and communication were gathered from school records and teachers, teaching assistants, practitioners and parents. Data were captured using still images and videos, children's recorded commentaries, conversations, written feedback and observation. Using grounded research methods, themes and categories arose directly from the collected data. Fluency, vocabulary, inventiveness and concentration were enhanced in the large majority of referred children. The research also found significant positive developments in motivation and confidence. Teachers and their assistants credited the drama intervention with notable improvements in attitude, behaviour and relationships over the year. Aspects of many children's psychological well-being also showed marked signs of progress when measured against original reasons for referral and normal expectations over a year. An unexpected outcome was evidence of heightened well-being of the teaching assistants involved. Findings compared well with expectations based upon Fredrickson's theory and also the theatre company's view that theatre-making promotes emotional awareness and empathy. Improvements in both children's well-being and communication were

  1. Seven Years of Permanent Running of MELFI-1 on Board the ISS and Utilisation of the Three MELFI Units Refrigeration Pool

    Science.gov (United States)

    Chegancas, Jean; Stephan, Hubertus; Jimenez, Jesus; Campana, Sharon; Hutchison, Susan

    2013-01-01

    The pool of three Minus Eighty Laboratory freezer for ISS (MELFI) units continues providing the scientific community with robust and permanent freezer and refrigeration capabilities for life science experiments on the International Space Station (ISS). Launched in 2006, the first unit will complete, by summer 2013, seven years of continuous operations without intervention on the internal Nitrogen gas cycle, while all necessary hardware and operations were initially planned for preventive maintenance every two years. This unit has demonstrated outstanding performance on orbit and proved the technical decisions made during the development program. Current utilization of MELFI units in the ISS is taking full benefit of the initial specifications, which allows for wide adaptations to cope with the mission scenario imposed by the life extension in orbit. The two other MELFI units, launched respectively in 2008 and 2009, are supporting the first unit providing additional conditioned volume necessary for the science on board, and also for preparing thermal mass used to protect the samples on their way down to earth. The MELFI pool is outfitted with all supporting hardware to allow for extended operation on orbit including preventive and corrective maintenance. The internal components were designed to allow for easy on board maintenance. Spare equipment was installed in the MELFI rack on ISS and specific maintenance means were developed which required crew training before the cold gas cycle could be accessed. The paper will present first how the design choices made for the initial missions are identifying features necessary for extended duration missions, and will then give highlights on the utilization of the MELFI refrigeration pool during the recent years in ISS.

  2. Multimodal lung cancer screening using the ITALUNG biomarker panel and low dose computed tomography. Results of the ITALUNG biomarker study.

    Science.gov (United States)

    Carozzi, Francesca Maria; Bisanzi, Simonetta; Carrozzi, Laura; Falaschi, Fabio; Lopes Pegna, Andrea; Mascalchi, Mario; Picozzi, Giulia; Peluso, Marco; Sani, Cristina; Greco, Luana; Ocello, Cristina; Paci, Eugenio

    2017-07-01

    Asymptomatic high-risk subjects, randomized in the intervention arm of the ITALUNG trial (1,406 screened for lung cancer), were enrolled for the ITALUNG biomarker study (n = 1,356), in which samples of blood and sputum were analyzed for plasma DNA quantification (cut off 5 ng/ml), loss of heterozygosity and microsatellite instability. The ITALUNG biomarker panel (IBP) was considered positive if at least one of the two biomarkers included in the panel was positive. Subjects with and without lung cancer diagnosis at the end of the screening cycle with LDCT (n = 517) were evaluated. Out of 18 baseline screen detected lung cancer cases, 17 were IBP positive (94%). Repeat screen-detected lung cancer cases were 18 and 12 of them positive at baseline IBP test (66%). Interval cancer cases (2-years) and biomarker tests after a suspect Non Calcific Nodule follow-up were investigated. The single test versus multimodal screening measures of accuracy were compared in a simulation within the screened ITALUNG intervention arm, considering screen-detected and interval cancer cases. Sensitivity was 90% at baseline screening. Specificity was 71 and 61% for LDCT and IBP as baseline single test, and improved at 89% with multimodal, combined screening. The positive predictive value was 4.3% for LDCT at baseline and 10.6% for multimodal screening. Multimodal screening could improve the screening efficiency at baseline and strategies for future implementation are discussed. If IBP was used as primary screening test, the LDCT burden might decrease of about 60%. © 2017 UICC.

  3. Feasibility study on the FAO chicken microsatellite panel to assess genetic variability in the turkey (Meleagris gallopavo

    Directory of Open Access Journals (Sweden)

    Elena Colombo

    2014-12-01

    Full Text Available The aim of this work was to study the feasibility of the Food and Agriculture Organization (FAO microsatellite panel developed for chickens to assess genetic variability in turkeys. Genomic DNA was extracted from a total of 37 blood samples collected from turkey of different breeds [15 Brianzolo (BR; 12 Colli Euganei (EU; 10 Nero d’Italia (NI], and all 31 chicken microsatellite markers recommended by the FAO were tested. The results show that 22 chicken markers out of 31 suggested by FAO guidelines can be applied to turkey populations. In particular, the multiplex groups confirmed in the turkey were the Multiplex Master Mix 1 (ADL0268, ADL0278, LEI0094, MCW0216, MCW0248 and the Master Mix 2 (MCW0034, MCW0069, MCW0081, MCW0222, MCW0295, whereas 13 microsatellites were amplified only under single polymerase chain reaction (PCR conditions. No PCR products were obtained for 9 markers (LEI0166, MCW0020, MCW0078, MCW0080, MCW0104, MCW0123, MCW0248, MCW0284 and MCW0330, which is 29% of the total markers used. A panel of 22 markers was used to assess genetic diversity in three turkey breeds and a total number of 63 alleles were found. Observed (Ho and expected (He heterozygosity and polymorphism information content (PIC values for each microsatellite and the relative mean values were also calculated. The mean values were 0.210, 0.250, 0.203 for Ho; 0.301, 0.348, 0.228 for He; and 0.265, 0.313, 0.199 for PIC in NI, BR and EU, respectively.

  4. Experimental study on the effects of trailing edge geometry on the propulsive performance and wake structure of bio-inspired pitching panels

    Science.gov (United States)

    King, Justin; Green, Melissa

    2017-11-01

    Force measurements and stereoscopic particle image velocimetry (SPIV) were used to characterize the propulsive performance and three-dimensional wake structure of rigid, acrylic pitching panels with various trailing edge geometries. Experiments were carried out on multiple panels with bio-inspired planforms that were pitched about their leading edge. A trapezoidal panel geometry with a straight trailing edge was chosen as a baseline case, and deviations from a trapezoid were studied using panels with either a concave or convex trailing edge Previous work by van Buren et al. (Physical Review Fluids, 2017) has established that parameters such as coefficient of thrust and propulsive efficiency can be affected by changes in the trailing edge shape of pitching panels. In the current work, SPIV data were collected across the spanwise extent of the wake, and it is demonstrated that spanwise vortices are organized to form a reverse von Karman vortex street across much of the spanwise extent of the wake. The spanwise vortices are oriented in accordance with the trailing edge shape, i.e. a concave trailing edge sheds spanwise vortices that are bent inwards while a convex trailing edge sheds spanwise vortices that are bent outwards. The SPIV results also provide further insight into the three-dimensional wake behavior and structure as it relates to propulsive performance. This work was supported by the Office of Naval Research under ONR Award No. N00014-14-1-0418.

  5. Thermal Analysis of Solar Panels

    Science.gov (United States)

    Barth, Nicolas; de Correia, João Pedro Magalhães; Ahzi, Saïd; Khaleel, Mohammad Ahmed

    In this work, we propose to analyze the thermal behavior of PV panels using finite element simulations (FEM). We applied this analysis to compute the temperature distribution in a PV panel BP 350 subjected to different atmospheric conditions. This analysis takes into account existing formulations in the literature and, based on NOCT conditions, meteorological data was used to validate our approach for different wind speed and solar irradiance. The electrical performance of the PV panel was also studied. The proposed 2D FEM analysis is applied to different region's climates and was also used to consider the role of thermal inertia on the optimization of the PV device efficiency.

  6. Modeling Longitudinal Relationships Between Habit and Physical Activity: Two Cross-Lagged Panel Design Studies in Older Adults.

    Science.gov (United States)

    van Bree, Rob J H; Bolman, Catherine; Mudde, Aart N; van Stralen, Maartje M; Peels, Denise A; de Vries, Hein; Lechner, Lilian

    2017-07-01

    These longitudinal studies in older adults targeted mediated relationships between habit and physical activity (PA). In The Netherlands two independent studies were conducted among 1976 (Study 1: Mage = 63.63, SD = 8.66, 30% functional limitations) and 2140 (Study 2: Mage = 62.75, SD = 8.57, 45% functional limitations) adults aged 50 years or older. Cross-lagged panel designs were applied to examine whether habit mediates the relationship between prior and later PA and whether PA simultaneously mediates the relationship between prior and later habit. Data on habit and PA were collected by means of questionnaires at baseline (t0) and at 6 (t1) and 12 (t2) months after baseline measurement. Results of structural equation modeling analyses were not unambiguous. Indications for the existence of both hypothesized mediation effects were found, but no clear, unequivocal pattern appeared. Somewhat more support was found for the PA-habit-PA path than for the habit-PA-habit path. More research is needed to draw more definitive conclusions.

  7. Reporting studies on time to diagnosis: proposal of a guideline by an international panel (REST)

    NARCIS (Netherlands)

    Launay, Elise; Cohen, Jérémie F.; Bossuyt, Patrick M.; Buekens, Pierre; Deeks, Jonathan; Dye, Timothy; Feltbower, Richard; Ferrari, Andrea; Kramer, Michael; Leeflang, Mariska; Moher, David; Moons, Karel G.; von Elm, Erik; Ravaud, Philippe; Chalumeau, Martin

    2016-01-01

    Studies on time to diagnosis are an increasing field of clinical research that may help to plan corrective actions and identify inequities in access to healthcare. Specific features of time to diagnosis studies, such as how participants were selected and how time to diagnosis was defined and

  8. Reporting studies on time to diagnosis: proposal of a guideline by an international panel (REST)

    NARCIS (Netherlands)

    Launay, Elise; Cohen, Jeremie F.; Bossuyt, Patrick M.; Buekens, Pierre; Deeks, Jonathan; Dye, Timothy; Feltbower, Richard; Ferrari, Andrea; Kramer, Michael; Leeflang, Mariska; Moher, David; Moons, Karel G.; von Elm, Erik; Ravaud, Philippe; Chalumeau, Martin

    2016-01-01

    Background: Studies on time to diagnosis are an increasing field of clinical research that may help to plan corrective actions and identify inequities in access to healthcare. Specific features of time to diagnosis studies, such as how participants were selected and how time to diagnosis was defined

  9. Income Inequality and Gambling: A panel study in the United States (1980-1997)

    NARCIS (Netherlands)

    Bol, T.; Lancee, B.; Steijn, S.

    2014-01-01

    While there are many studies that examine the consequences of increasing income inequality, its effects on gambling behavior have not yet been studied. In this article, we argue that income inequality increases the average expenditure on gambling. Using longitudinal state-level data for the United

  10. Air pollution and respiratory health of children: the PEACE panel study in Teplice, Czech Republic.

    NARCIS (Netherlands)

    Kotesovec, F.; Vitnerova, N.; Leixner, M.; Benes, I.; Skoorkovsky, J.; Roemer, W.

    1998-01-01

    As part of a multicentre study (the Pollution Effects on Asthmatic Children in Europe (PEACE) project) the acute effects of air pollution on the health of susceptible children was investigated. Eighty nine children in the urban and 77 children in the rural area were followed during the study period

  11. Cost-efficient selection of a marker panel in genetic studies

    Science.gov (United States)

    Jamie S. Sanderlin; Nicole Lazar; Michael J. Conroy; Jaxk Reeves

    2012-01-01

    Genetic techniques are frequently used to sample and monitor wildlife populations. The goal of these studies is to maximize the ability to distinguish individuals for various genetic inference applications, a process which is often complicated by genotyping error. However, wildlife studies usually have fixed budgets, which limit the number of geneticmarkers available...

  12. How do retirement dynamics influence mental well-being in later life? A 10-year panel study.

    Science.gov (United States)

    Dingemans, Ellen; Henkens, Kène

    2015-01-01

    Empirical studies have consistently shown the negative impact of involuntary retirement on mental well-being. However, few studies have thus far investigated the degree to which post-retirement work affects late-life outcomes. The present study improves our understanding of the impact of retirement on the self-efficacy and life satisfaction among older adults by focusing on the combined impact of retirement voluntariness and participation in post-retirement work. By using panel data on retirement behavior in the Netherlands, we estimate fixed effects and multilevel models to explain (intra-)individual changes in self-efficacy and life satisfaction over a 10-year period in which most participants made the transition to retirement. The results indicate that involuntary retirement is associated with decreases in both self-efficacy and life satisfaction in later life. Whereas involuntary retirees who participate in bridge jobs show no changes in life satisfaction, those involuntary retirees without bridge jobs experience a decline in life satisfaction. In addition, we found enhanced levels of life satisfaction for voluntary retirees in bridge employment. The association with self-efficacy was less pronounced. These results suggest that the characteristics of the retirement process influence changes in mental well-being in later life. Specifically, bridge employment alleviates the negative consequences of involuntary retirement and even seems to enhance post-retirement well-being for voluntary retirees.

  13. VARIABILITY STUDIES ON STRENGTH AND FIBRE PROPERTIES OF Bambusa vulgaris Schrad. FOR PANEL PRODUCTS

    Directory of Open Access Journals (Sweden)

    Kehinde Sesan AINA

    2012-03-01

    Full Text Available A variability study on strength and fibre properties of bamboo (Bambusa vulgaris was investigated in this study. Bamboo bole length of two geographical locations (Ibadan and Ilorin at percentage of (10, 30, 50, 70 and 90 were used to determine the fibre properties such as fibre length, fibre diameter, lumen width, cell wall thickness, runkel ratio, flexibility coefficient and relative fibre length. The strength properties of bamboolaminated boards were also investigated in this study with the effect of different variable factors, such as the adhesive type (Top bond and Urea formaldehyderide, bole portion (top, middle and base and bole thickness size (5mm x 20mm and 10mm x 20mm. Mechanical properties, such as the modulus of rupture, impact bending strength, compression strength, shear strength in both parallel and perpendicular direction were determined. The results show that there is potential for using bamboo for the production of paper and as building and structural material.

  14. Seven-Year Follow-Up Study of Symptoms in Asylum Seekers and Refugees With PTSD Treated With Trauma-Focused Groups.

    NARCIS (Netherlands)

    Drožđek, B; Kamperman, A.M.; Tol, W.A.; Knipscheer, Jeroen; Kleber, Rolf

    OBJECTIVE: To examine sustainability of symptom outcomes of a 1-year phase-based trauma-focused, multimodal, and multicomponent group therapy in a day treatment program for posttraumatic stress disorder (PTSD) over an average period of 7 years. METHOD: Iranian and Afghan patients (N = 69) were

  15. Does Formal Education in Leadership Improve Public Managers’ Leadership Behavior? A Panel Study

    DEFF Research Database (Denmark)

    Sørensen, Peter

    2018-01-01

    Participation in formal leadership education is assumed to have an impact on public managers’ leadership behavior. However, there is a gap in the literature exploring whether this assumption can be supported. This study aims to contribute in filling this gap. Using descriptive statistics and a pa...

  16. Panel discussion: cCinical pet neurotransmitter metabolism and receptor binding studies of brain

    International Nuclear Information System (INIS)

    Frey, K.A.

    1991-01-01

    Following presentations on applications and results of PET imaging in Parkinson's disease (PD), Alzheimer's disease (AD), and refractory temporal lobe epilepsy, additional aspects of PET use in evaluating neurologic disease were discussed. Several questions addressed imaging of the dopamine (DA) synapse in PD. Discussion centered around reasons for focal hypometabolism of the association cortex in AD but not of the striatum in PD as well as potential applications of metabolic and presynaptic DA measurements in the diagnostic evaluation of Parkinsonian syndromes. The specificity of fluoroDOPA (FD) uptake following PD treatment by adrenal or substantia nigra transplantation was addressed. Blood-brain-barrier disruption and the metabolic instability of FD were discussed as underlying causes of increased tracer accumulation reported in the literature. The session then turned to dementia and the problem of establishing a definite diagnosis.The roles of PET and SPECT imaging in these areas is relatively new but is very promising. The session concluded with discussion of the possibility of activation studies with neurotransmitter ligands. The design and interpretation of such studies are quite complex. Physiologic stimulation studies frequently result in altered local cerebral perfusion; it will be necessary to distinguish differences in ligand distribution arising form blood flow changes from possible alterations in receptor availability. These interactions may also confound radioligand studies following pharmacologic interventions with unlabeled drugs

  17. Air pollution and respiratory health of children: the PEACE panel study in Prague, Czech Republic.

    NARCIS (Netherlands)

    Vondra, V.; Branis, M.; Reisova, M.; Maly, M.; Hoek, G.

    1998-01-01

    A multicentre study (Pollution Effects on Asthmatic Children in Europe (PEACE)) project investigated the relationship between the air pollution and daily variation of respiratory health in children with chronic respiratory symptoms. Data were collected on 66 children in Prague and 68 children in

  18. U.S. adults' pornography viewing and support for abortion: a three-wave panel study.

    Science.gov (United States)

    Tokunaga, Robert S; Wright, Paul J; McKinley, Christopher J

    2015-01-01

    Pornography consumption may affect judgments on a wide range of sexual and reproductive topics. The present study hypothesized that the consistent images projected in pornography affect sexual scripts related to abortion judgments. National, three-wave longitudinal data gathered from U.S. adults were employed to examine associations between earlier pornography consumption and subsequent support for abortion. The findings suggested that prior pornography consumption may lead to later support for abortion. This study provides additional evidence of pornography's socializing impact, particularly for the older White segment of the population, and adds to knowledge about what environmental factors influence judgments about abortion. Mechanisms that may explain how pornography viewing shapes support for abortion are discussed.

  19. Panel of polymorphic heterologous microsatellite loci to genotype critically endangered Bengal tiger: a pilot study

    OpenAIRE

    Mishra, Sudhanshu; Singh, Sujeet Kumar; Munjal, Ashok Kumar; Aspi, Jouni; Goyal, Surendra Prakash

    2014-01-01

    In India, six landscapes and source populations that are important for long-term conservation of Bengal tigers (Panthera tigris tigris) have been identified. Except for a few studies, nothing is known regarding the genetic structure and extent of gene flow among most of the tiger populations across India as the majority of them are small, fragmented and isolated. Thus, individual-based relationships are required to understand the species ecology and biology for planning effective conservation...

  20. On the consistency of personality types across adulthood: latent profile analyses in two large-scale panel studies.

    Science.gov (United States)

    Specht, Jule; Luhmann, Maike; Geiser, Christian

    2014-09-01

    Consistency and change in personality were analyzed by examining personality types across adulthood and old age using data from 2 nationally representative panel studies from Germany (N = 14,718; 16-82 years) and Australia (N = 8,315; 15-79 years). In both samples, the Big Five personality traits were measured twice across a period of 4 years. Latent profile analyses and latent profile transition analyses revealed 4 main findings: First, solutions with 3 (in the German sample) or 4 (in the Australian sample) personality types were found to be most interpretable. Second, measurement invariance tests revealed that these personality types were consistent across all age groups but differed slightly between men and women. Third, age was related to the number of individuals classified within each personality type. Namely, there were more resilients and fewer undercontrollers in older compared with younger age groups. Fourth, there was strong consistency of personality type membership across a period of 4 years in both genders and most age cohorts. Comparatively less consistency across time was found for undercontrollers and individuals in old age. Taken together, these findings show that in the 2 nations studied here, personality types were highly consistent across gender, age, and time. 2014 APA, all rights reserved

  1. A panel study of airborne particulate matter concentration and impaired cardiopulmonary function in young adults by two different exposure measurement

    Science.gov (United States)

    Hu, Li-Wen; Qian, Zhengmin (Min); Bloom, Michael S.; Nelson, Erik J.; Liu, Echu; Han, Bin; Zhang, Nan; Liu, Yimin; Ma, Huimin; Chen, Duo-Hong; Yang, Bo-Yi; Zeng, Xiao-Wen; Chen, Wen; Komppula, Mika; Leskinen, Ari; Hirvonen, Maija-Riitta; Roponen, Marjut; Jalava, Pasi; Bai, Zhipeng; Dong, Guang-Hui

    2018-05-01

    This study sought to clarify the correlation of individual exposure measurements and PM2.5 measurements collected at regulatory monitoring sites in short-term panel study settings. To achieve this goal, 30 young, healthy adult participants were assigned to three groups with 4 samplers in each group to collect individual exposures during four weekends in March 2016. Participants also completed cardiopulmonary function tests during the same periods. For comparison, ambient air pollution data were obtained from the Air Pollution Surveillance Network in Guangzhou, China. The 8-h ambient pollutant averages and group sampler concentrations were used as separate indicators of air pollution exposure. Results showed that the 8-h mean concentration of personal PM2.5 exposure was 65.09 ± 22.18 μg/m3, which was 24.34 μg/m3 statistically higher than the ambient concentrations over the same period (p urban areas may experience reduced lung function (lower MMEF), even after just 8 h of exposure to PM2.5 and PM10.

  2. Panel of polymorphic heterologous microsatellite loci to genotype critically endangered Bengal tiger: a pilot study.

    Science.gov (United States)

    Mishra, Sudhanshu; Singh, Sujeet Kumar; Munjal, Ashok Kumar; Aspi, Jouni; Goyal, Surendra Prakash

    2014-01-03

    In India, six landscapes and source populations that are important for long-term conservation of Bengal tigers (Panthera tigris tigris) have been identified. Except for a few studies, nothing is known regarding the genetic structure and extent of gene flow among most of the tiger populations across India as the majority of them are small, fragmented and isolated. Thus, individual-based relationships are required to understand the species ecology and biology for planning effective conservation and genetics-based individual identification has been widely used. But this needs screening and describing characteristics of microsatellite loci from DNA from good-quality sources so that the required number of loci can be selected and the genotyping error rate minimized. In the studies so far conducted on the Bengal tiger, a very small number of loci (n = 35) have been tested with high-quality source of DNA, and information on locus-specific characteristics is lacking. The use of such characteristics has been strongly recommended in the literature to minimize the error rate and by the International Society for Forensic Genetics (ISFG) for forensic purposes. Therefore, we describe for the first time locus-specific genetic and genotyping profile characteristics, crucial for population genetic studies, using high-quality source of DNA of the Bengal tiger. We screened 39 heterologous microsatellite loci (Sumatran tiger, domestic cat, Asiatic lion and snow leopard) in captive individuals (n = 8), of which 21 loci are being reported for the first time in the Bengal tiger, providing an additional choice for selection. The mean relatedness coefficient (R = -0.143) indicates that the selected tigers were unrelated. Thirty-four loci were polymorphic, with the number of alleles ranging from 2 to 7 per locus, and the remaining five loci were monomorphic. Based on the PIC values (> 0.500), and other characteristics, we suggest that 16 loci (3 to 7 alleles) be used for genetic

  3. Final report of the Multiprogram Laboratory Panel Energy Research Advisory Board. Volume II. Support studies

    International Nuclear Information System (INIS)

    Spiewak, I.; Guthrie, M.P.; Nichols, J.P.; Preston, E.L.; West, C.D.; Wilbanks, T.J.; Wilkes, B.Y.; Zerby, A.C.

    1982-09-01

    Volume II - support studies for nine national laboratories include: report of statistical data on the multiprogram laboratories; examples of national laboratory use in foreign countries; domestic models for national laboratory utilization; relationships of laboratories with industry and universities; uses of laboratories for training industrial R and D personnel; legal mandates and constraints on the national laboratories; with appendices on facts about Harwell, CEN-Saclay, TNO, Studsvik, and JAERI-Tokai; the Requirements Boards of the United Kingdom Department of Industry; impact of President's FY 1983 budget; and the PNL experiment

  4. Prevalence of metabolic syndrome according to Adult Treatment Panel III and International Diabetes Federation criteria: a population-based study.

    Science.gov (United States)

    Bener, Abdulbari; Zirie, Mahmoud; Musallam, Manal; Khader, Yousef S; Al-Hamaq, Abdulla O A A

    2009-06-01

    The objective of the study was to examine the prevalence of metabolic syndrome among adult Qatari population according to the revised criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and the International Diabetes Federation (IDF), assess which component contributed to the increased risk of the metabolic syndrome, and identify the characteristics of the subjects with metabolic syndrome. This was a cross-sectional study. The survey was carried out in urban and semiurban primary health-care centers. The survey was conducted from January, 2007, to July, 2008, among Qatari nationals above 20 years of age. Of the 1496 subjects who were approached to participate in the study, 1204 (80.5%) gave their consent. Face-to-face interviews were conducted using a structured questionnaire followed by laboratory tests. Metabolic syndrome was defined using the NCEP ATP III as well as IDF criteria. The overall prevalence of metabolic syndrome in studied subjects was 26.5% and 33.7% according to ATP III and IDF criteria (P education and physical activity. Also, the prevalence of metabolic syndrome was more common in women. Among the components of metabolic syndrome, central obesity was significantly higher in the studied subjects. The IDF definition of metabolic syndrome gave a higher prevalence in all age groups. The overall prevalence of metabolic syndrome and its components according to IDF criteria was higher in the studied subjects than the estimates given by the ATP III. Multivariate logistics regression analysis (ATP III and IDF) showed that age and BMI were significant contributors for metabolic syndrome. Both definitions strongly supported age and obesity as associated factors for metabolic syndrome. The current study found a high prevalence of metabolic syndrome among Qataris. There was a steady increase in the prevalence of metabolic syndrome through the decades, independent of the definition. Age and BMI were important

  5. Modeling individual exposures to ambient PM2.5 in the diabetes and the environment panel study (DEPS).

    Science.gov (United States)

    Breen, Michael; Xu, Yadong; Schneider, Alexandra; Williams, Ronald; Devlin, Robert

    2018-06-01

    Air pollution epidemiology studies of ambient fine particulate matter (PM 2.5 ) often use outdoor concentrations as exposure surrogates, which can induce exposure error. The goal of this study was to improve ambient PM 2.5 exposure assessments for a repeated measurements study with 22 diabetic individuals in central North Carolina called the Diabetes and Environment Panel Study (DEPS) by applying the Exposure Model for Individuals (EMI), which predicts five tiers of individual-level exposure metrics for ambient PM 2.5 using outdoor concentrations, questionnaires, weather, and time-location information. Using EMI, we linked a mechanistic air exchange rate (AER) model to a mass-balance PM 2.5 infiltration model to predict residential AER (Tier 1), infiltration factors (F inf_home , Tier 2), indoor concentrations (C in , Tier 3), personal exposure factors (F pex , Tier 4), and personal exposures (E, Tier 5) for ambient PM 2.5 . We applied EMI to predict daily PM 2.5 exposure metrics (Tiers 1-5) for 174 participant-days across the 13 months of DEPS. Individual model predictions were compared to a subset of daily measurements of F pex and E (Tiers 4-5) from the DEPS participants. Model-predicted F pex and E corresponded well to daily measurements with a median difference of 14% and 23%; respectively. Daily model predictions for all 174 days showed considerable temporal and house-to-house variability of AER, F inf_home , and C in (Tiers 1-3), and person-to-person variability of F pex and E (Tiers 4-5). Our study demonstrates the capability of predicting individual-level ambient PM 2.5 exposure metrics for an epidemiological study, in support of improving risk estimation. Copyright © 2018. Published by Elsevier B.V.

  6. Experimental and theoretical studies into the stress-strain state of the purlin supported by sandwich panels

    Directory of Open Access Journals (Sweden)

    Danilov Aleksandr Ivanovich

    2014-12-01

    Full Text Available In the article, the co-authors analyze the findings of the experimental and theoretical studies into the real behaviour of a thin-walled cold-formed purlin as part of the roof structure made of sandwich panels. The roof structure fragment was tested; displacements and stresses, that the purlin was exposed to, were identified in respect of each loading increment. NASTRAN software was employed to perform the numerical analysis of the roof structure, pre-exposed to experimental tests, in the geometrically and physically non-linear setting. The finite element model, generated as a result (the numerical analysis pattern, is sufficiently well-set, given the proposed grid of elements, and it ensures reasonably trustworthy results. The diagrams describing the stress/displacement to the load ratio and obtained numerically are consistent with those generated experimentally. The gap between the critical loading values reaches 4%. Analytical and experimental findings demonstrate their close conformity, and this fact may justify the application of the numerical model, generated within the framework of this research project, in the course of any further research actions. The co-authors have identified that the exhaustion of the bearing capacity occurs due to the loss of the buckling resistance as a result of the lateral torsional buckling.

  7. Cross Talk Study to the Single Photon Response of a Flat Panel PMT for the RICH Upgrade at LHCb

    CERN Multimedia

    Arnaboldi, C; Calvi, M; Fanchini, E; Gotti, C; Maino, M; Matteuzzi, C; Perego, D L; Pessina, G; Wang, J C

    2009-01-01

    The Ring Imaging CHerenkov, RICH, detector at LHCb is now readout by Hybrid Photon Detectors. In view of its upgrade a possible option is the adoption of the flat panel Photon Multipliers Tubes, PMT. An important issue for the good determination of the rings produced in the sensitive media is a negligible level of cross talk. We have experimentally studied the cross talk from the 64x64 pixels of the H9500 PMT from Hamamatsu. Results have shown that at the single photon signal level, as expected at LHCb, the statistics applied to the small number of electrons generated at the first dynode of the PMT chain leads to a cross talk mechanism that must be interpreted in term of the percentage of the number of induced signals rather than on the amplitude of the induced signals. The threshold to suppress cross talk must be increased to a significant fraction of the single photon signal for the worst case. The number of electrons generated at the first dynode is proportional to the biasing voltage. Measurements have sh...

  8. Study on the performance of infrared thermal imaging light source for detection of impact defects in CFRP composite sandwich panels

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hee Sang [R and D, Korea Research Institute of Smart Material and Structures System Association, Daejeon (Korea, Republic of); Choi, Man Yong; Kwon, Koo Ahn; Park, Jeong Hak; Choi, Won Jae [Safety measurement center, Korea research Institute of Standards and Science, Daejeon (Korea, Republic of); Jung, Hyun Chul [Dept. of Mechanical Engineering Chosun University, Gwangju (Korea, Republic of)

    2017-04-15

    Recently, composite materials have been mainly used in the main wings, ailerons, and fuselages of aircraft and rotor blades of helicopters. Composite materials used in rapid moving structures are subject to impact by hail, lightning, and bird strike. Such an impact can destroy fiber tissues in the composite materials as well as deform the composite materials, resulting in various problems such as weakened rigidity of the composite structure and penetration of water into tiny cracks. In this study, experiments were conducted using a 2 kW halogen lamp which is most frequently used as a light source, a 2 kW near-infrared lamp, which is used for heating to a high temperature, and a 6 kW xenon flash lamp which emits a large amount of energy for a moment. CFRP composite sandwich panels using Nomex honeycomb core were used as the specimens. Experiments were carried out under impact damages of 1, 4 and 8 J. It was found that the detection of defects was fast when the xenon flash lamp was used. The detection of damaged regions was excellent when the halogen lamp was used. Furthermore, the near-infrared lamp is an effective technology for showing the surface of a test object.

  9. A comparative study of scintillator combining methods for flat-panel X-ray image sensors

    Science.gov (United States)

    Kim, M. S.; Lim, K. T.; Kim, G.; Cho, G.

    2018-02-01

    An X-ray transmission imaging based on scintillation detection method is the most widely used radiation technique particularly in the medical and industrial areas. As the name suggests, scintillation detection uses a scintillator as an intermediate material to convert incoming radiation into visible-light particles. Among different types of scintillators, CsI(Tl) in a columnar configuration is the most popular type used for applications that require an energy less than 150 keV due to its capability in obtaining a high spatial resolution with a reduced light spreading effect. In this study, different methods in combining a scintillator with a light-receiving unit are investigated and their relationships are given in terms of the image quality. Three different methods of combining a scintillator with a light-receiving unit are selected to investigate their performance in X-ray imaging: upward or downward oriented needles structure of CsI(Tl), coating layer deposition around CsI(Tl), and insertion of FOP. A charge-coupled device was chosen to serve as the light-receiving unit for the proposed system. From the result, the difference of needle directions in CsI(Tl) had no significant effects in the X-ray image. In contrast, deposition of the coating material around CsI(Tl) showed 17.3% reduction in the DQE. Insertion of the FOP increased the spatial resolution by 38%, however, it decreased the light yield in the acquired image by 56%. In order to have the maximum scintillation performance in X-ray imaging, not only the reflection material but also the bonding method must be considered when combining the scintillator with the light-receiving unit. In addition, the use of FOP should be carefully decided based on the purpose of X-ray imaging, e.g., image sharpness or SNR.

  10. Family effects on the rurality of GP's work location: a longitudinal panel study.

    Science.gov (United States)

    McGrail, Matthew R; Russell, Deborah J; O'Sullivan, Belinda G

    2017-10-19

    Reduced opportunities for children's schooling and spouse's/partner's employment are identified internationally as key barriers to general practitioners (GPs) working rurally. This paper aims to measure longitudinal associations between the rurality of GP work location and having (i) school-aged children and (ii) a spouse/partner in the workforce. Participants included 4377 GPs responding to at least two consecutive annual surveys of the Medicine in Australia: Balancing Employment and Life (MABEL) national longitudinal study between 2008 and 2014. The main outcome, GP work location, was categorised by remoteness and population size. Five sequential binary school-age groupings were defined according to whether a GP had no children, only preschool children (aged 0-4 years), at least one primary-school child (aged 5-11 years), at least one child in secondary school (aged 12-18 years), and all children older than secondary school (aged ≥ 19). Partner in the workforce was defined by whether a GP had a partner who was either currently working or looking for work, or not. Separate generalised estimating equation models, which aggregated consecutive annual observations per GP, tested associations between work location and (i) educational stages and (ii) partner employment, after adjusting for key covariates. Male GPs with children in secondary school were significantly less likely to work rurally (inclusive of > 50 000 regional centres through to the smallest rural towns of locations were not significantly associated with the educational stage of their children. Having a partner in the workforce was not associated with work location for male GPs, whereas female GPs with a partner in the workforce were significantly less likely to work in smaller rural/remote communities (location is related to key family needs which differ according to GP gender and educational stages of children. Such non-professional factors are likely to be dynamic across the GP's lifespan and

  11. The suitability of caffeinated drinks for children: a systematic review of randomised controlled trials, observational studies and expert panel guidelines.

    Science.gov (United States)

    Ruxton, C H S

    2014-08-01

    The increased availability of caffeinated drinks raises questions about the level of caffeine that is appropriate for children, as well as the benefits and risks associated with their consumption. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, this systematic review evaluates evidence from randomised controlled trials investigating the effects of caffeine on cognition, behaviour, mood and exercise performance in children. Observational studies and expert panel guidelines are also discussed. One hundred and nine studies were found, with 11 randomised controlled trials and 13 observational studies meeting the criteria. High caffeine intakes (e.g. >5 mg kg(-1) body weight day(-1)) were associated with an increased risk of anxiety and withdrawal symptoms. However, smaller amounts were not linked with such effects and may benefit cognitive function and sports performance based on adult studies. The evidence suggests that children and adolescents should limit daily caffeine consumption to 2.5 mg kg(-1) body weight day(-1), equating to one or two cups of tea or one small cup of coffee. Lower contributors of caffeine, such as tea, may be more appropriate for children because they contribute to daily fluid intakes and provide flavonoids. By contrast, caffeinated soft drinks may be less suitable options for children as a result of their acidity, higher caffeine content, presence of added sugar (in some cases) and absence of bioactive compounds. More studies are needed to determine the intakes that represent a risk and whether there may be benefits for alertness and sports performance with moderate intakes of caffeine. © 2013 The British Dietetic Association Ltd.

  12. Hepatitis virus panel

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003558.htm Hepatitis virus panel To use the sharing features on this page, please enable JavaScript. The hepatitis virus panel is a series of blood tests used ...

  13. A Parameter Study of Coupling Properties in Finite Element Models of Single-Stud Double-Plate Panels

    DEFF Research Database (Denmark)

    Dickow, Kristoffer Ahrens; Domadiya, Parthkumar Gandalal; Andersen, Lars Vabbersgaard

    2011-01-01

    Lightweight building techniques are currently progressing fast and using such structures for multi-storey multi-family dwellings is becoming part of the industry standard. Partitions in lightweight buildings are often constructed as plates on frame structures made of either wood or steel. In any...... case the low frequency sound transmission is often an issue that needs attention. The present paper utilizes a finite element model of a single-stud double-plate panel structure to investigate how different couplings between the plates and the frame structure affect the direct sound transmission. Four...... and the load acts as a diffuse field on one side of the panel. The obtained results indicate that in order to accurately model sound transmission through a double-plate panel structure, the choice of coupling is an important factor....

  14. Comprehensive metabolic panel

    Science.gov (United States)

    Metabolic panel - comprehensive; Chem-20; SMA20; Sequential multi-channel analysis with computer-20; SMAC20; Metabolic panel 20 ... Normal values for the panel tests are: Albumin : 3.4 to 5.4 g/dL (34 to 54 g/L) Alkaline phosphatase : 44 to 147 ...

  15. Centers for Disease Control review panel's recommendations on health effects and epidemiological studies of operations at the Savannah River Plant, Aiken, South Carolina. Public comment and meeting report

    International Nuclear Information System (INIS)

    1985-05-01

    Based on the request of the US Department of Energy, the Centers for Disease Control of the US Department of Health and Human Services organized a panel to review the feasibility and usefulness of conducting further epidemiologic studies of delayed health effects around the Department of Energy's Savannah River Plant. The review and recommendations of the panel were documented in a report entitled Epidemiologic Projects Considered Possible to Undertake in Populations Around the Savannah River Plant. On November 30, 1984, the Department of Energy announced in the Federal Register (49 FR 47095) the conduct of a public meeting and a 30-day public comment period between December 1 and December 30, 1984, on the recommendations of the review panel. Based on the requests of individuals and representatives of organizations attending the December 18, 1984, public meetings, the Department of Energy subsequently announced in the Federal Register on December 31, 1984 (49 FR 50767) an extension of the public comment period to January 31, 1985. This report documents the public meeting and comment process, and provides responses to the public comments that were submitted during this process. In addition, this report contains the Department of Energy's position based on the recommendations of the Centers for Disease Control review panel and the public comments. 23 refs., 16 tabs

  16. A Study on Large Display Panel Design for the Countermeasures against Team Errors within the Main Control Room of APR-1400

    International Nuclear Information System (INIS)

    Kim, Sa Kil; Lee, Yong Hee

    2015-01-01

    The personal aspect of human errors has been mainly overcome by virtue of the education and training. However, in the system aspect, the education and training system needs to be reconsidered for more effective reduction of human errors affected from various systems hazards. Traditionally the education and training systems are mainly not focused on team skills such as communication, situational awareness, and coordination, etc. but individual knowledge, skill, and attitude. However, the team factor is one of the crucial issues to reduce the human errors in most industries. In this study, we identify the emerging types of team errors, especially, in digitalized control room of nuclear power plants such as the APR-1400 main control room. Most works in nuclear industry are to be performed by a team of more than two persons. Even though the individual errors can be detected and recovered by the qualified others and/or the well trained team, it is rather seldom that the errors by team could be easily detected and properly recovered by the team itself. Note that the team is defined as two or more people who are appropriately interacting with each other, and the team is a dependent aggregate, which accomplishes a valuable goal. Team error is one of the typical organizational errors that may occur during performing operations in nuclear power plants. The large display panel is a representative feature of digitalized control room. As a group-view display, the large display panel provides plant overview to the operators. However, in terms of team performance and team errors, the large display panel is on a discussion board still because the large display panel was designed just a concept of passive display. In this study, we will propose revised large display panel which is integrated with several alternative interfaces against feasible team errors

  17. The relationship between academic achievement and nonmarital teenage childbearing: evidence from the panel study of income dynamics.

    Science.gov (United States)

    Lou, Cary; Thomas, Adam

    2015-06-01

    Females who do well in school are less likely than those who do poorly to experience a nonmarital teenage birth. However, little is known about which dimensions of academic achievement are the most strongly related to teenage childbearing, or about whether the relationship between achievement and childbearing varies according to the presence of other behavioral problems. Individual-level and family-level data from the Panel Study of Income Dynamics, combined with information on contextual state-level economic and policy measures, were used to study nonmarital childbearing between the ages of 16 and 19 among 701 females who turned 16 between 2000 and 2007. Multivariate logistic regression analyses examined the relationship between the probability of nonmarital teenage childbearing and age-standardized scores on academic assessments of letter-word identification, passage comprehension and applied problem-solving ability. Scores on the passage comprehension and applied problem-solving subtests were strongly associated with the probability of experiencing a nonmarital teenage birth among respondents who had relatively few behavioral problems. For this group, an increase of one standard deviation in the score on either assessment was associated with a reduction of about 50% in the risk of experiencing a nonmarital teenage birth. However, no evidence was found of an equivalent relationship among respondents with more pronounced behavioral problems or for the letter-word identification assessment. Future research should continue to explore the possibility that improvements in academic achievement may help to reduce the rate of nonmarital teenage childbearing. Copyright © 2015 by the Guttmacher Institute.

  18. Reprint of: Effects of Asian dust on daily cough occurrence in patients with chronic cough: A panel study

    Science.gov (United States)

    Higashi, Tomomi; Kambayashi, Yasuhiro; Ohkura, Noriyuki; Fujimura, Masaki; Nakai, Satoshi; Honda, Yasushi; Saijoh, Kiyofumi; Hayakawa, Kazuichi; Kobayashi, Fumihisa; Michigami, Yoshimasa; Olando, Anyenda Enoch; Hitomi, Yoshiaki; Nakamura, Hiroyuki

    2014-11-01

    Asian dust, known as kosa in Japanese, is a major public health concern. In this panel study, we evaluated the effects of exposure to kosa on daily cough occurrence. The study subjects were 86 patients being treated for asthma, cough variant asthma, or atopic cough in Kanazawa University Hospital from January 2011 to June 2011. Daily mean concentrations of kosa and spherical particles were obtained from light detection and ranging (LIDAR) measurements, and were categorized from Grade 1 (0 μg/m3) to 5 (over 100 μg/m3). The association between kosa and cough was analyzed by logistic regression with a generalized estimating equation. Kosa effects on cough were seen for all Grades with potential time lag effect. Particularly at Lag 0 (the day of exposure), a dose-response relationship was observed: the odds ratios for Grades 2, 3, 4, and 5 above the referent (Grade 1) were 1.111 (95% confidence interval (CI): 0.995-1.239), 1.171 (95% CI: 1.006-1.363), 1.357 (95% CI: 1.029-1.788), and 1.414 (95% CI: 0.983-2.036), respectively. Among the patients without asthma, the association was higher: the odds ratios for Grades 2, 3, 4 and 5 were 1.223 (95% CI: 0.999-1.497), 1.309 (95% CI: 0.987-1.737), 1.738 (95% CI: 1.029-2.935) and 2.403 (95% CI: 1.158-4.985), respectively. These associations remained after adjusting for the concentration of spherical particles or particulate matter with an aerodynamic diameter of less than 2.5 μm (PM2.5). Our findings demonstrate that kosa is an environmental factor which induces cough in a dose-response relationship.

  19. Pathways to Reciprocated Friendships: A Cross-Lagged Panel Study on Young Adolescents' Anger Regulation towards Friends.

    Science.gov (United States)

    von Salisch, Maria; Zeman, Janice L

    2018-03-01

    Adolescents' close friendships are an important and unique learning context in which adolescents can practice and hone their emotion regulation skills within an egalitarian, supportive relationship structure that provides important feedback on the effectiveness of the regulation strategies. This longitudinal study examined whether adolescents' involvement in supportive reciprocal friendships influenced the way in which they regulated angry feelings arising in these friendships. A sample of 299 German adolescents began a 30-month, 3-wave longitudinal study in grade 7 (151 boys, M age = 12.6 years; 100% White). They completed a social network inventory (LueNIC), a peer-nomination measure, and the questionnaire on Strategies of Anger Regulation for Adolescents (SAR-A) in every wave. Cross-lagged-panel modeling indicated a pattern of socialization effects even when controlling for previous friendship involvement, previous anger regulation, peer acceptance, gender, classroom membership, and possible friendship selection influences. Adolescents with more reciprocal friends at Time 1 (T1) reported using aggressive strategies of anger regulation (i.e., verbal and relational aggression, fantasies of revenge) and ignoring the friend less often at Time 2 (T2). Similar results were obtained between T2 and Time 3 (T3). There was a marginally significant effect for one of three non-aggressive strategies such that a higher involvement in friendships at T2 explained more reappraisal of the anger-eliciting event at T3 but significant effects did not emerge for the strategies of redirection of attention and explanation and reconciliation. The results are discussed within a socialization of emotion framework with implications for social skills training modules.

  20. A parametric study on supersonic/hypersonic flutter behavior of aero-thermo-elastic geometrically imperfect curved skin panel

    NARCIS (Netherlands)

    Abbas, L.K.; Rui, X.; Marzocca, P.; Abdalla, M.; De Breuker, R.

    2011-01-01

    In this paper, the effect of the system parameters on the flutter of a curved skin panel forced by a supersonic/hypersonic unsteady flow is numerically investigated. The aeroelastic model investigated includes the third-order piston theory aerodynamics for modeling the flow-induced forces and the

  1. Study of the effect of a By-catch Reduction Panel in a twin-trawl on reducing plaice discards

    NARCIS (Netherlands)

    Marlen, van B.; Helmond, van A.T.M.; Pasterkamp, T.L.; Bol, R.A.

    2008-01-01

    Comparative fishing trials were conducted in November 2008 on the euro-cutter MFV TH-7 “Adriana Maria” on fishing grounds in the North Sea to investigate the effect of By-catch Reduction Panels inserted in a twin-trawl. In a total of 17 experimental hauls two nets were fished simultaneously, a

  2. Media Exposure, Current and Future Body Ideals, and Disordered Eating among Preadolescent Girls: A Longitudinal Panel Study

    Science.gov (United States)

    Harrison, Kristen; Hefner, Veronica

    2006-01-01

    Internalization of the thin body ideal is considered by many to account for the relationship between media exposure and disordered eating among girls and young women, but almost all supporting research has employed adolescent and adult samples. Using longitudinal panel survey data collected from 257 preadolescent girls at 2 points in time 1 year…

  3. The Impact of Energy taxes on Competitiveness and Output: A Panel Regression Study of 56 European Industry Sectors

    DEFF Research Database (Denmark)

    Enevoldsen, Martin K.; Andersen, Mikael Skou

    2008-01-01

    The focus of this paper is the extent to which energy taxes - via the resulting increase in real energy prices, or in their own right - reduce or enhance industrial competitiveness. From a panel data set covering 56 industry sectors throughout Europe over the period 1990-2003, we estimate how cha...

  4. Influence of PM1 and PM2.5 on lung function parameters in healthy schoolchildren-a panel study.

    Science.gov (United States)

    Zwozdziak, A; Sówka, I; Willak-Janc, E; Zwozdziak, J; Kwiecińska, K; Balińska-Miśkiewicz, W

    2016-12-01

    To evaluate lung function responses to short-term indoor PM 1 and PM 2.5 concentrations, we conducted a panel study of healthy schoolchildren aged 13-14 years. The following lung function parameters FVC, FEV 1 , PEF, and mid expiratory flows MEF 25 , MEF 50 , and MEF 75 were measured in 141 schoolchildren of the secondary school in Wroclaw, Poland in years 2009-2010. On days when spirometry tests were conducted, simultaneously, PM 1 and PM 2.5 samples were collected inside the school premises. Information about differentiating factors for children including smoking parents, sex, living close to busy streets, dust, mold, and pollen allergies were collected by means of questionnaires. To account for repeated measurements, the method of generalized estimating equations (GEE) was used. The GEE models for the entire group of children revealed the adverse effects (p < 0.05) of PM 1 and PM 2.5 . Small differences in effects estimates per interquartile range (IQR) of PM 1 and PM 2.5 on MEF 25 (5.1 and 4.8 %), MEF 50 (3.7 and 3.9 %), MEF 75 (3.5 and 3.6 %) and FEV 1 (1.3 and 1.0 %) imply that PM 1 was likely the component of PM 2.5 that might have a principal health effect on these lung function parameters. However, the reduction of FVC and PEF per IQR for PM 2.5 (2.1 and 5.2 %, respectively) was higher than for PM 1 (1.0 and 4.4 %, respectively). Adjustment for potential confounders did not change the unadjusted analysis.

  5. The impact of a novel transendometrial approach for caesarean myomectomy on obstetric outcomes of subsequent pregnancy: a longitudinal panel study.

    Science.gov (United States)

    Huang, S Y; Shaw, S W; Su, S Y; Li, W F; Peng, H H; Cheng, P J

    2018-03-01

    To evaluate the obstetric and surgical outcomes of a novel transendometrial approach for myomectomy during caesarean section in subsequent pregnancies. Longitudinal panel study. Chang Gung Memorial Hospital, Taiwan, with approximately 5000 births per annum. Pregnant women complicated with uterine myoma. Sixty-three pregnant women who received transendometrial myomectomy during the first caesarean delivery reported a subsequent live pregnancy and planned an elective repeat caesarean delivery. Obstetric outcomes consisted of gestational age at birth, newborn weight, Apgar score, birthweight adequacy, uterine rupture, placental abruption, placenta praevia, placenta accreta, spontaneous preterm birth and preterm premature rupture of membranes. Surgical outcomes consisted of surgical time, blood loss, blood transfusion, postoperative fever, length of hospital stay and mean adhesion score. The mean gestational age at birth and newborn weight at the subsequent caesarean section were superior to those at the first caesarean delivery. Spontaneous preterm birth, small-for-gestational-age infants and preterm premature rupture of membranes occurred more often in the first pregnancy than in the subsequent pregnancy. The mean surgical time was shorter for the subsequent caesarean delivery than for the first caesarean delivery combined with myomectomy. The other surgical composite outcomes of blood loss, blood transfusion, postoperative fever, length of hospital stay and mean adhesion score were similar across the two stages of caesarean deliveries. The novel transendometrial approach for caesarean myomectomy may improve the obstetric outcomes of subsequent pregnancy without causing any additional immediate and long-term adverse surgical outcomes. Transendometrial caesarean myomectomy may improve future obstetric outcomes. © 2017 Royal College of Obstetricians and Gynaecologists.

  6. Ultrafine particles and platelet activation in patients with coronary heart disease – results from a prospective panel study

    Directory of Open Access Journals (Sweden)

    Wichmann H Erich

    2007-01-01

    Full Text Available Abstract Background Epidemiological studies on health effects of air pollution have consistently shown adverse cardiovascular effects. Toxicological studies have provided evidence for thrombogenic effects of particles. A prospective panel study in a susceptible population was conducted in Erfurt, Germany, to study the effects of daily changes in ambient particles on various blood cells and soluble CD40ligand (sCD40L, also known as CD154, a marker for platelet activation that can cause increased coagulation and inflammation. Blood cells and plasma sCD40L levels were repeatedly measured in 57 male patients with coronary heart disease (CHD during winter 2000/2001. Fixed effects linear regression models were applied, adjusting for trend, weekday and meteorological parameters. Hourly data on ultrafine particles (UFP, number concentration of particles from 0.01 to 0.1 μm, mass concentration of particles less than 10 and 2.5 μm in diameter (PM10, PM2.5, accumulation mode particle counts (AP, 0.1–1.0 μm, elemental and organic carbon, gaseous pollutants and meteorological data were collected at central monitoring sites. Results An immediate increase in plasma sCD40L was found in association with UFP and AP (% change from geometric mean: 7.1; CI: [0.1, 14.5] and 6.9; CI: [0.5, 13.8], respectively. Platelet counts decreased in association with UFP showing an immediate, a three days delayed (lag 3 and a 5-day average response (% change from the mean: -1.8; CI: [-3.4,-0.2]; -2.4; CI: [-4.5,-0.3] and -2.2; CI: [-4.0,-0.3] respectively. Conclusion The increased plasma sCD40L levels support the hypothesis that higher levels of ambient air pollution lead to an inflammatory response in patients with CHD thus providing a possible explanation for the observed association between air pollution and cardiovascular morbidity and mortality in susceptible parts of the population.

  7. Paneling architectural freeform surfaces

    KAUST Repository

    Eigensatz, Michael

    2010-07-26

    The emergence of large-scale freeform shapes in architecture poses big challenges to the fabrication of such structures. A key problem is the approximation of the design surface by a union of patches, socalled panels, that can be manufactured with a selected technology at reasonable cost, while meeting the design intent and achieving the desired aesthetic quality of panel layout and surface smoothness. The production of curved panels is mostly based on molds. Since the cost of mold fabrication often dominates the panel cost, there is strong incentive to use the same mold for multiple panels. We cast the major practical requirements for architectural surface paneling, including mold reuse, into a global optimization framework that interleaves discrete and continuous optimization steps to minimize production cost while meeting user-specified quality constraints. The search space for optimization is mainly generated through controlled deviation from the design surface and tolerances on positional and normal continuity between neighboring panels. A novel 6-dimensional metric space allows us to quickly compute approximate inter-panel distances, which dramatically improves the performance of the optimization and enables the handling of complex arrangements with thousands of panels. The practical relevance of our system is demonstrated by paneling solutions for real, cutting-edge architectural freeform design projects. © 2010 ACM.

  8. Paneling architectural freeform surfaces

    KAUST Repository

    Eigensatz, Michael

    2010-07-25

    The emergence of large-scale freeform shapes in architecture poses big challenges to the fabrication of such structures. A key problem is the approximation of the design surface by a union of patches, so-called panels, that can be manufactured with a selected technology at reasonable cost, while meeting the design intent and achieving the desired aesthetic quality of panel layout and surface smoothness. The production of curved panels is mostly based on molds. Since the cost of mold fabrication often dominates the panel cost, there is strong incentive to use the same mold for multiple panels. We cast the major practical requirements for architectural surface paneling, including mold reuse, into a global optimization framework that interleaves discrete and continuous optimization steps to minimize production cost while meeting user-specified quality constraints. The search space for optimization is mainly generated through controlled deviation from the design surface and tolerances on positional and normal continuity between neighboring panels. A novel 6-dimensional metric space allows us to quickly compute approximate inter-panel distances, which dramatically improves the performance of the optimization and enables the handling of complex arrangements with thousands of panels. The practical relevance of our system is demonstrated by paneling solutions for real, cutting-edge architectural freeform design projects.

  9. Tsimane' Amazonian Panel Study (TAPS): the first 5 years (2002-2006) of socioeconomic, demographic, and anthropometric data available to the public.

    Science.gov (United States)

    Leonard, William R; Godoy, Ricardo

    2008-07-01

    The Tsimane' Amazonian Panel Study (TAPS) is making available the first five years (2002-2006, inclusive) of annual socioeconomic, demographic, and anthropometric data available to the public. The information comes from a foraging-farming society of native Amazonians in Bolivia and includes 13 villages, 332 households, and 1985 people who have been tracked annually since 2002. The article provides a brief overview of the data covered and the steps needed to access the data.

  10. A preliminary study of head-up display assessment techniques. 2: HUD symbology and panel information search time

    Science.gov (United States)

    Guercio, J. G.; Haines, R. F.

    1978-01-01

    Twelve commercial pilots were shown 50 high-fidelity slides of a standard aircraft instrument panel with the airspeed, altitude, ADI, VSI, and RMI needles in various realistic orientations. Fifty slides showing an integrated head-up display (HUD) symbology containing an equivalent number of flight parameters as above (with flight path replacing VSI) were also shown. Each subject was told what flight parameter to search for just before each slide was exposed and was given as long as needed (12 sec maximum) to respond by verbalizing the parameter's displayed value. The results for the 100-percent correct data indicated that: there was no significant difference in mean reaction time (averaged across all five flight parameters) between the instrument panel and HUD slides; and a statistically significant difference in mean reaction time was found in responding to different flight parameters.

  11. The Quality of Financial Information and Stock Market Development: A Panel Data Study for the European Economies

    OpenAIRE

    Lazarov, Darko; Lakovic, Tanja; Miteva-Kacarski, Emilija

    2017-01-01

    The main aim of the paper is to investigate whether the quality of financial information facilitates and promotes the stock market development. We test this hypothesis by using a sample of 36 European economies in the period 2006–2012 based on dynamic panel regression (system GMM) approach. The strength of auditing and reporting standards (SARS) is used as a measure of financial information quality, while the stock market capitalization relative to GDP measures the stock market development. T...

  12. The impact of government subsidies and enterprises’ R&D investment: A panel data study from renewable energy in China

    International Nuclear Information System (INIS)

    Yu, Feifei; Guo, Yue; Le-Nguyen, Khuong; Barnes, Stuart J.; Zhang, Weiting

    2016-01-01

    In this research, we aim to understand the influence of government subsidies on enterprises’ research and development (R&D) investment behavior, particularly in China’s renewable energy sector. We are also interested in examining how the attributes of enterprise ownership act as a moderating variable for the relationship between government subsidies and R&D investment behavior. Three classical panel data analysis models including the pooled ordinary least squares (OLS) model, the fixed effect model and the random effect model are employed. We find that government subsidies have a significant crowding out influence on enterprises’ R&D investment behavior and that the influence is further moderated by the attributes of enterprise ownership. Moreover, a panel threshold regression model is used to demonstrate how the influence of government subsidies on enterprises’ R&D investment behavior will change when government subsidies increase. Two thresholds, 0.6% and 10.1%, are identified. We recommend that relevant government departments should motivate enterprise R&D investment behavioral intention by increasing subsidies within a certain range. Different attributes of enterprise ownership should also be considered as part of policy reform and re-structuring relating to government subsidies. - Highlights: • Government subsidies have a significant crowding-out effect on enterprises’ R&D. • The moderating role of the attributes of company ownership is examined. • A panel threshold regression model is used to explore the influence of subsidy. • First examining the effect of subsidy in the renewable industry in China.

  13. Titanium Honeycomb Panel Testing

    Science.gov (United States)

    Richards, W. Lance; Thompson, Randolph C.

    1996-01-01

    Thermal-mechanical tests were performed on a titanium honeycomb sandwich panel to experimentally validate the hypersonic wing panel concept and compare test data with analysis. Details of the test article, test fixture development, instrumentation, and test results are presented. After extensive testing to 900 deg. F, non-destructive evaluation of the panel has not detected any significant structural degradation caused by the applied thermal-mechanical loads.

  14. Changes in Social Capital and Cigarette Smoking Behavior Over Time: A Population-Based Panel Study of Temporal Relationships.

    Science.gov (United States)

    Lindström, Martin; Giordano, Giuseppe N

    2016-11-01

    Identifying factors that influence individuals' smoking behavior remains a huge public health concern. This study aimed to investigate changes in individuals' cigarette smoking while considering well-known smoking determinants, including social capital, its presence being postulated to reduce smoking. From British Household Panel Survey data, two baseline smoking cohorts were created ("smoking" and "not smoking"). The same individuals from this nationally representative sample (N T = 8114, aged 16-91 years) were interviewed on four occasions between years 2000 and 2007 to investigate changes in cigarette smoking behavior. Logistic regression models with random effects compensated for within-individual behavior over time. Temporal pathways were investigated by lagging independent variables (t - 1) in relation to our cigarette-use outcome at time (t). Active social participation at (t - 1) was positively associated with smoking cessation at (t) (odds ratio [OR] = 1.39; 95% confidence interval [CI] [1.07-1.82]). Separating from one's spouse at (t - 1) increased risk for smoking relapse/initiation at (t) (OR = 6.63; 95% CI [1.70-28.89]). Conversely, being married protected against smoking cigarettes (OR = 1.87; 95% CI [1.15-3.04]). These associations held in our robustness checks. Initial marital breakdown predicted a high risk of smoking relapse/initiation. The timing of this life event provides a critical window where adverse smoking behavior might occur. Conversely, the positive effects of active social participation on cigarette cessation remained consistent, its absence further predicting smoking relapse/initiation. Robustness of results confirms the important role that active participation has on cigarette smoking behavior. Group smoking cessation interventions could harness participatory elements to better achieve their goals. By investigating temporal relationships between well-known smoking determinants and cigarette smoking outcomes, we identified that being

  15. PM2.5 metal exposures and nocturnal heart rate variability: a panel study of boilermaker construction workers

    Directory of Open Access Journals (Sweden)

    Herrick Robert F

    2008-07-01

    Full Text Available Abstract Background To better understand the mechanism(s of particulate matter (PM associated cardiovascular effects, research priorities include identifying the responsible PM characteristics. Evidence suggests that metals play a role in the cardiotoxicity of fine PM (PM2.5 and in exposure-related decreases in heart rate variability (HRV. We examined the association between daytime exposure to the metal content of PM2.5 and night HRV in a panel study of boilermaker construction workers exposed to metal-rich welding fumes. Methods Twenty-six male workers were monitored by ambulatory electrocardiogram (ECG on a workday while exposed to welding fume and a non-workday (baseline. From the ECG, rMSSD (square root of the mean squared differences of successive intervals was summarized over the night (0:00–7:00. Workday, gravimetric PM2.5 samples were analyzed by x-ray fluorescence to determine metal content. We used linear mixed effects models to assess the associations between night rMSSD and PM2.5 metal exposures both with and without adjustment for total PM2.5. Matched ECG measurements from the non-workday were used to control for individual cardiac risk factors and models were also adjusted for smoking status. To address collinearity between PM2.5 and metal content, we used a two-step approach that treated the residuals from linear regression models of each metal on PM2.5 as surrogates for the differential effects of metal exposures in models for night rMSSD. Results The median PM2.5 exposure was 650 μg/m3; median metal exposures for iron, manganese, aluminum, copper, zinc, chromium, lead, and nickel ranged from 226 μg/m3 to non-detectable. We found inverse linear associations in exposure-response models with increased metal exposures associated with decreased night rMSSD. A statistically significant association for manganese was observed, with a decline of 0.130 msec (95% CI: -0.162, -0.098 in night rMSSD for every 1 μg/m3 increase in

  16. Panel summary report

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    Previous Advisory Group Meetings have led to IAEA Technical Reports No.15=5 (1974) on thermal discharge, 118 (1970) and 169 (1975) on sampling, storage and analysis methods for marine radioactivity studies, 167 (1975) on design of marine biological studies permitting comparative evaluation, and 172 (1976) on the effects of ionizing radiation on aquative organisms and eco-systems. The aim of the present report was a bringing into perspective not only problems designing radioecological experiments but to describe reliable experimental methodology suitable for a successful evaluation of radioactivity cycling, and of the effects of such radioactive additions to aquatic environments, as a result of nuclear activities. Specific examples are described. Individual studies presented to the Panel have been treated in detail, and constitute 19 separate INIS entries

  17. Solar reflection panels

    Science.gov (United States)

    Diver, Jr., Richard B.; Grossman, James W [Albuquerque, NM; Reshetnik, Michael [Boulder, CO

    2006-07-18

    A solar collector comprising a glass mirror, and a composite panel, wherein the back of the mirror is affixed to a front surface of the composite panel. The composite panel comprises a front sheet affixed to a surface of a core material, preferably a core material comprising a honeycomb structure, and a back sheet affixed to an opposite surface of the core material. The invention may further comprise a sealing strip, preferably comprising EPDM, positioned between the glass mirror and the front surface of the composite panel. The invention also is of methods of making such solar collectors.

  18. Natural Disasters, Economic Growth and Sustainable Development in China―An Empirical Study Using Provincial Panel Data

    Directory of Open Access Journals (Sweden)

    Ji Guo

    2015-12-01

    Full Text Available Using a newly developed integrated indicator system with entropy weighting, we analyzed the panel data of 577 recorded disasters in 30 provinces of China from 1985–2011 to identify their links with the subsequent economic growth. Meteorological disasters promote economic growth through human capital instead of physical capital. Geological disasters did not trigger local economic growth from 1999–2011. Generally, natural disasters overall had no significant impact on economic growth from 1985–1998. Thus, human capital reinvestment should be the aim in managing recoveries, and it should be used to regenerate the local economy based on long-term sustainable development.

  19. Puncture panel optimization

    International Nuclear Information System (INIS)

    Glass, R.E.; Longenbaugh, R.S.

    1986-01-01

    Sandia National Laboratories developed the TRansUranic PACkage Transporter (TRUPACT) to transport defense contact-handled transuranic wastes. The package has been designed to meet the normal and hypothetical accident conditions in 10CFR71 which includes the demonstrated ability to survive a 1-meter drop onto a mild steel pin. The puncture protection is provided by puncture resistant panels. In conjunction with the development of TRUPACT, a series of experiments has been conducted to reduce the weight of the puncture resistant panels. The initial scoping tests resulted in a preliminary design incorporating 30 layers of Kevlar. This design has been shown to meet the regulatory puncture test. To reduce the weight of this panel, subscale tests were conducted on panels utilizing Kevlar yarns with varying mass per unit length (denier) as well as different resins. This paper reviews the testing undertaken in the original panel development and discusses the results obtained from the recent subscale and full-scale optimization tests

  20. Solar panel cleaning robot

    Science.gov (United States)

    Nalladhimmu, Pavan Kumar Reddy; Priyadarshini, S.

    2018-04-01

    As the demand of electricity is increasing, there is need to using the renewable sources to produce the energy at present of power shortage, the use of solar energy could be beneficial to great extent and easy to get the maximum efficiency. There is an urgent in improving the efficiency of solar power generation. Current solar panels setups take a major power loss when unwanted obstructions cover the surface of the panels. To make solar energy more efficiency of solar array systems must be maximized efficiency evaluation of PV panels, that has been discussed with particular attention to the presence of dust on the efficiency of the PV panels have been highlighted. This paper gives the how the solar panel cleaning system works and designing of the cleaning system.

  1. Performance Study of an aSi Flat Panel Detector for Fast Neutron Imaging of Nuclear Waste

    Energy Technology Data Exchange (ETDEWEB)

    Schumann, M.; Mauerhofer, E. [Institute of Energy and Climate Research - Nuclear Waste Management and Reactor Safety, Forschungszentrum Juelich GmbH, 52425 Juelich (Germany); Engels, R.; Kemmerling, G. [Central Institute for Engineering, Electronics and Analytics - Electronic Systems, Forschungszentrum Juelich GmbH, 52425 Juelich (Germany); Frank, M. [MATHCCES - Department of Mathematics, RWTH Aachen University, 52062 Aachen (Germany); Havenith, A.; Kettler, J.; Klapdor-Kleingrothaus, T. [Institute of Nuclear Engineering and Technology Transfer, RWTH Aachen University, 52062 Aachen (Germany); Schitthelm, O. [Corporate Technology, Siemens AG, 91058 Erlangen (Germany)

    2015-07-01

    Radioactive waste must be characterized to check its conformance for intermediate storage and final disposal according to national regulations. For the determination of radio-toxic and chemo-toxic contents of radioactive waste packages non-destructive analytical techniques are preferentially used. Fast neutron imaging is a promising technique to assay large and dense items providing, in complementarity to photon imaging, additional information on the presence of structures in radioactive waste packages. Therefore the feasibility of a compact Neutron Imaging System for Radioactive waste Analysis (NISRA) using 14 MeV neutrons is studied in a cooperation framework of Forschungszentrum Juelich GmbH, RWTH Aachen University and Siemens AG. However due to the low neutron emission of neutron generators in comparison to research reactors the challenging task resides in the development of an imaging detector with a high efficiency, a low sensitivity to gamma radiation and a resolution sufficient for the purpose. The setup is composed of a commercial D-T neutron generator (Genie16GT, Sodern) with a surrounding shielding made of polyethylene, which acts as a collimator and an amorphous silicon flat panel detector (aSi, 40 x 40 cm{sup 2}, XRD-1642, Perkin Elmer). Neutron detection is achieved using a general propose plastic scintillator (EJ-260, Eljen Technology) linked to the detector. The thermal noise of the photodiodes is reduced by employing an entrance window made of aluminium. Optimal gain and integration time for data acquisition are set by measuring the response of the detector to the radiation of a 500 MBq {sup 241}Am-source. Detector performance was studied by recording neutron radiography images of materials with various, but well known, chemical compositions, densities and dimensions (Al, C, Fe, Pb, W, concrete, polyethylene, 5 x 8 x 10 cm{sup 3}). To simulate gamma-ray emitting waste radiographs in presence of a gamma-ray sources ({sup 60}Co, {sup 137}Cs, {sup 241

  2. ASIST 2003: Part II: Panels.

    Science.gov (United States)

    Proceedings of the ASIST Annual Meeting, 2003

    2003-01-01

    Forty-six panels address topics including women in information science; users and usability; information studies; reference services; information policies; standards; interface design; information retrieval; information networks; metadata; shared access; e-commerce in libraries; knowledge organization; information science theories; digitization;…

  3. Adjective semantics, world knowledge and visual context: Comprehension of size terms by two- to seven-year-old Dutch-speaking children

    NARCIS (Netherlands)

    Tribushinina, E.

    2013-01-01

    The interpretation of size terms involves constructing contextually-relevant reference points by combining visual cues with knowledge of typical object sizes. This study aims to establish at what age children learn to integrate these two sources of information in the interpretation process and tests

  4. Integrated evaluation of the performance of a more than seven year old permeable reactive barrier at a site contaminated with chlorinated aliphatic hydrocarbons (CAHs)

    DEFF Research Database (Denmark)

    Muchitsch, Nanna; Nooten, Thomas Van; Bastiaens, Leen

    2011-01-01

    role in the long-term performance. An integrated study was performed on the Vapokon permeable reactive barrier (PRB) in Denmark by groundwater and iron core sample characterization. The detailed field groundwater sampling carried out from more than 75 well screens up and downstream the barrier showed...

  5. Make Your Own Solar Panel.

    Science.gov (United States)

    Suzuki, David

    1992-01-01

    Presents an activity in which students make a simulated solar panel to learn about the principles behind energy production using solar panels. Provides information about how solar panels function to produce energy. (MCO)

  6. C1-C2 transarticular screw fixation for atlantoaxial instability due to rheumatoid arthritis: a seven-year analysis of outcome.

    LENUS (Irish Health Repository)

    Nagaria, Jabir

    2009-12-15

    STUDY DESIGN.: Observational study. Retrospective analysis of prospectively collected data. OBJECTIVE.: The purpose of this article was to report long-term (minimum 7 years) clinical and radiologic outcome of our series of patients with Rheumatoid Arthritis who underwent transarticular screw fixation to treat atlantoaxial subluxation. SUMMARY OF BACKGROUND DATA.: The indications for intervention in patients with atlantoaxial instability are pain, myelopathy, and progressive neurologic deficit. The various treatment options available for these patients are isolated C1-C2 fusion, occipitocervical fusion with or without transoral surgery. Review of current literature suggests that C1-C2 transarticular screw fixation has significant functional benefits, although there is discrepancy in this literature regarding improvement in function following surgery. METHODS.: Myelopathy was assessed using Ranawat myelopathy score and Myelopathy Disability Index. Pain scores were assessed using Visual Analogue Scale. The radiologic imaging was assessed and the following data were extracted; atlanto-dens interval, space available for cord, presence of signal change on T2 weighted image, and fusion rates. RESULTS.: Thirty-seven patients, median age 56, were included in the study. Average duration of neck symptoms was 15.8 months. Average duration of rheumatoid arthritis before surgery was 20.6 years. Preoperative symptoms: suboccipital pain in 26 patients; neck pain, 32; myelopathy, 22; and 5 were asymptomatic. After surgery: suboccipital pain, 2; neck pain, 3; and myelopathy, 10. Ninety percent patients with neck and suboccipital pain improved after surgery in their Visual Analogue pain scores, with all of them having >50% improvement in VAS scores (6.94-2.12 [P < 0.05]).Preoperative Ranawat grade was as follows: grade 1 in 15 patients, grade 2 in 7, and grade 3a in 14, grade 3b in 1.After surgery: grade 1 in 27 patients, grade 2 in 7, grade 3a in 1, and grade 3b in 2. The mean

  7. Long-term immunogenicity of two pediatric doses of combined hepatitis A and B or monovalent hepatitis B vaccine in 8 to 10-year-old children and the effect of a challenge dose given seven years later.

    Science.gov (United States)

    Gilca, Vladimir; Dionne, Marc; Boulianne, Nicole; Murphy, Donald; De Serres, Gaston

    2009-10-01

    A total of 465 children aged 8 to 10 years were vaccinated with 2 doses of Recombivax-HB 2.5 microg (RB) or Twinrix-Junior 10 microg/360 EL.U (TX), according to a 0 and 6 months schedule. Seven years postsecond dose, a challenge dose of vaccine was given. All vaccinees in the TX and 98% in the RB group showed an anamnestic response. Vaccination at the age of 8 to 10 years with two-pediatric doses of TX or RB given with a 6 months interval induces a long-lasting immunity in most vaccinees.

  8. The effects of HIV/AIDS on economic growth and human capitals: a panel study evidence from Asian countries.

    Science.gov (United States)

    Roy, Shongkour

    2014-01-01

    Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) affects economic growths by reducing the human capitals are among the most poorly understood aspect of the AIDS epidemic. This article analyzes the effects of the prevalence of HIV and full-blown AIDS on a country's human capitals and economic growths. Using a fixed effect model for panel data 1990-2010 from the Asia, I explored the dynamic relationships among HIV/AIDS, economic growths, and human capitals within countries over time. The econometric effects concerned that HIV/AIDS plays an important role in the field of economic growths and it is measured as a change in real gross domestic product (GDP) per capita and human capitals. The modeling results for the Asian countries indicates HIV/AIDS prevalence that has a hurtful effect on GDP per capita by reducing human capitals within countries over time.

  9. OPERATION POLLINATOR: A NEW WAY FOR THE PROTECTION AND IMPLEMENTATION OF INSECT POLLINATORS IN DIFFERENT AGROECOSYSTEM - RESULTS OF SEVEN YEARS OF EXPERIMENT IN ITALY

    Directory of Open Access Journals (Sweden)

    Tiziano GARDI

    2015-10-01

    Full Text Available Pollination by native honeybees and other pollinating insects is very important for the economy of farmer and the ecosystems. For these reasons, in Italy, a project between the Faculty of Agriculture of the University of Perugia (currently DSA3 and Syngenta Crop Protection S.p.a. (currently Syngenta Italia S.p.a. started in order to verify if the presence of autochtonous vegetation could be not only attractive for the pollinating insects but also fit for safeguarding the useful insects and increasing their populations. This study indicates that it is practical for growers to create valuable habitats suitable for natural pollinators. Moreover, it is possible to significantly reduce soil erosion and protect the water resources from pollution through a careful planning and management. Based on 5-years results in Italy and others European Countries, actually “Operation Pollinator” is applied in 13 European Countries besides Swizerland, UK and USA with the aim to safeguard native pollinating insects and honeybees. Our study, connected to the “Operation Pollinator”, can be considered as forerunner of the Greening Measures within the new EU Common Agricultural Policy (2014-2020.

  10. Online market research panel members as controls in case-control studies to investigate gastrointestinal disease outbreaks: early experiences and lessons learnt from the UK.

    Science.gov (United States)

    Mook, P; McCormick, J; Kanagarajah, S; Adak, G K; Cleary, P; Elson, R; Gobin, M; Hawker, J; Inns, T; Sinclair, C; Trienekens, S C M; Vivancos, R; McCarthy, N D

    2018-03-01

    Established methods of recruiting population controls for case-control studies to investigate gastrointestinal disease outbreaks can be time consuming, resulting in delays in identifying the source or vehicle of infection. After an initial evaluation of using online market research panel members as controls in a case-control study to investigate a Salmonella outbreak in 2013, this method was applied in four further studies in the UK between 2014 and 2016. We used data from all five studies and interviews with members of each outbreak control team and market research panel provider to review operational issues, evaluate risk of bias in this approach and consider methods to reduce confounding and bias. The investigators of each outbreak reported likely time and cost savings from using market research controls. There were systematic differences between case and control groups in some studies but no evidence that conclusions on the likely source or vehicle of infection were incorrect. Potential selection biases introduced by using this sampling frame and the low response rate are unclear. Methods that might reduce confounding and some bias should be balanced with concerns for overmatching. Further evaluation of this approach using comparisons with traditional methods and population-based exposure survey data is recommended.

  11. Seven year satellite observations of the mean structures and variabilities in the regional aerosol distribution over the oceanic areas around the Indian subcontinent

    Directory of Open Access Journals (Sweden)

    S. K. Nair

    2005-09-01

    Full Text Available Aerosol distribution over the oceanic regions around the Indian subcontinent and its seasonal and interannual variabilities are studied using the aerosol optical depth (AOD derived from NOAA-14 and NOAA-16 AVHRR data for the period of November 1995–December 2003. The air-mass types over this region during the Asian summer monsoon season (June–September are significantly different from those during the Asian dry season (November–April. Hence, the aerosol loading and its properties over these oceanic regions are also distinctly different in these two periods. During the Asian dry season, the Arabian Sea and Bay of Bengal are dominated by the transport of aerosols from Northern Hemispheric landmasses, mainly the Indian subcontinent, Southeast Asia and Arabia. This aerosol transport is rather weak in the early part of the dry season (November–January compared to that in the later period (February–April. Large-scale transport of mineral dust from Arabia and the production of sea-salt aerosols, due to high surface wind speeds, contribute to the high aerosol loading over the Arabian Sea region during the summer monsoon season. As a result, the monthly mean AOD over the Arabian Sea shows a clear annual cycle with the highest values occurring in July. The AOD over the Bay of Bengal and the Southern Hemisphere Indian Ocean also displays an annual cycle with maxima during March and October, respectively. The amplitude of the annual variation is the largest in coastal Arabia and the least in the Southern Hemisphere Indian Ocean. The interannual variability in AOD is the largest over the Southeast Arabian Sea (seasonal mean AOD varies from 0.19 to 0.42 and the northern Bay of Bengal (seasonal mean AOD varies from 0.24 to 0.39 during the February–April period and is the least over the Southern Hemisphere Indian Ocean. This study also investigates the altitude regions and pathways of dominant aerosol transport by combining the AOD distribution with

  12. NAS Panel faults export controls

    Science.gov (United States)

    Katzoff, Judith A.

    A study prepared by a top-level panel says that current export controls on militarily sensitive U.S. technology may be “overcorrecting” previous weaknesses in that system, resulting in “a complex and confusing control system” that makes it more difficult for U.S. businesses to compete in international markets. Moreover, this control system has “an increasingly corrosive effect” on U.S. relations with allies. The panel recommended that the United States concentrate more effort on bringing about uniformity in the export control policies of countries belonging to the Coordinating Committee on Multilateral Export Controls (CoCom), i.e., most of the member nations in NATO (the North Atlantic Treaty Organization) and Japan.The 21-member panel was appointed by the Committee on Science, Engineering, and Public Policy (COSEPUP), a joint unit of the National Academy of Sciences (NAS), the National Academy of Engineering (NAE), and the Institute of Medicine (IOM). The panel, composed of administrators, researchers, and former government officials, was chaired by AGU member Lew Allen, Jr., director of the Jet Propulsion Laboratory (Pasadena, Calif.) and former chief of staff of the U.S. Air Force. Their report was supported by NAS funds, by a number of private organizations (including AGU), by the U.S. Departments of Commerce, Defense, Energy, and State, by the National Science Foundation, and by the National Aeronautics and Space Administration.

  13. Seven-year review of dental foundation year 2/senior house officer training at the Oral and Maxillofacial Surgery Unit in Oxford.

    Science.gov (United States)

    Garg, M; Wong, L; Dhariwal, D

    2017-10-01

    The dental senior house officer (SHO)/dental foundation year 2 (DF2) posts in Oxford have provided hospital-based training for dentists, but in 2013 the Oral and Maxillofacial Surgery (OMFS) Unit withdrew from DF2 training because persistent negative feedback from the dental deanery varied from that obtained internally. We sent questionnaires to a consecutive group of 62 dentists who had worked at the John Radcliffe Hospital, Oxford, between 2006 and 2013 to find out about their experience of the posts. Forty responded (65% response rate). We analysed their expectations, the support provided, their experience of teaching and training, the opportunities available, and free-text feedback about the post and their current posts. They had all found the job helpful, and had gained generic, dental, medical, and surgical skills. The overall mean (SD) score for the post was 8 (2) on a Likert scale of 1-10 (with 10 being excellent). When they completed the questionnaire between December 2013 and July 2014, 18 respondents were working as general dental practitioners and four were training for a career in OMFS. The study showed that work as a dental SHO or DF2 has multiple benefits. We hope that our findings will help to improve OMFS training posts for dental core trainees in Oxford. Copyright © 2017 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  14. Latino children’s autonomic nervous system reactivity moderates the relations between cumulative socioeconomic adversity in the first five years and externalizing behavior problems at seven years

    Directory of Open Access Journals (Sweden)

    Abbey Alkon

    2016-05-01

    Full Text Available Background: Thirty-seven percent of Hispanic and Latino children under 5 years of age are living in poverty in the United States. Children growing up under conditions of cumulative adversity are at much greater risk for compromised psychosocial adjustment with long-lasting ramifications for mental and physical health. This study assessed whether the relations between adversity early in life and later externalizing behaviors was moderated by children’s autonomic nervous system (ANS reactivity for immigrant, poor, MexicanAmerican children. Methods: A cumulative socioeconomic adversity index of children’s exposure to poverty, father’s absence, household crowding, mothers speaking Spanish, and poor housing condition at 6 months and 1, 3.5, and 5 years of age was calculated. At 5 years, ANS profiles during resting and social- and emotion-evoking challenges were calculated as combined parasympathetic and sympathetic difference scores. At 7 years, parents assessed children’s externalizing behavior problems. Results: Multiple regression models (n=220 showed that the relations between cumulative socioeconomic adversity and externalizing behaviors were moderated by children’s ANS profiles of coactivation during a social, not emotion-evoking, challenge, controlling for relevant covariates. Conclusions: Children living in adverse conditions early in life with specific psychobiologic responses to social challenges may be at risk for developing externalizing behavior problems later in life.

  15. The hypothalomo-pituitary-adrenal system in liquidators of the Chernobyl accident consequences: summing up the seven-year follow-up

    International Nuclear Information System (INIS)

    Mitryaeva, N.A.

    1996-01-01

    The function of the hypothalamo-pituitary-adrenal system was studied over time (1986-1993) in 500 liquidators of the Chernobyl accident consequences with external exposure dose of 250 mSv. The concentrations of hydrocortisone, ACTH, and β-endorphine in the peripheral blood were radioimmunoassayed at rest and during functional loading. Glucocorticoids were measured in the urine by thin-layer chromatography. The number of glucocorticoid receptors in peripheral blood lymphocytes was assessed by the radioreceptor method. Stable hypercorticalism in the presence of reduced β-endorphine and increased ACTH levels was observed in the majority of examinees during the first years after the accident. Six years after the accident the above parameters were normal at rest, although during functional loading disorders in the reserve potential of the hypothalamo-pituitary-adrenal system were observed, which deteriorated its adaptation to changes int he environment. It is advisable to single out high risk groups of subjects with disadaptation disorders for regular check-ups among the liquidators. 10 refs.; 3 figs.; 4 tabs

  16. Seven years of postseismic deformation following the 2003 Mw = 6.8 Zemmouri earthquake (Algeria) from InSAR time series

    KAUST Repository

    Cetin, Esra

    2012-05-28

    We study the postseismic surface deformation of the Mw 6.8, 2003 Zemmouri earthquake (northern Algeria) using the Multi-Temporal Small Baseline InSAR technique. InSAR time series obtained from 31 Envisat ASAR images from 2003 to 2010 reveal sub-cm coastline ground movements between Cap Matifou and Dellys. Two regions display subsidence at a maximum rate of 2 mm/yr in Cap Djenet and 3.5 mm/yr in Boumerdes. These regions correlate well with areas of maximum coseismic uplifts, and their association with two rupture segments. Inverse modeling suggest that subsidence in the areas of high coseismic uplift can be explained by afterslip on shallow sections (<5 km) of the fault above the areas of coseismic slip, in agreement with previous GPS observations. The earthquake impact on soft sediments and the ground water table southwest of the earthquake area, characterizes ground deformation of non-tectonic origin. The cumulative postseismic moment due to 7 years afterslip is equivalent to an Mw 6.3 earthquake. Therefore, the postseismic deformation and stress buildup has significant implications on the earthquake cycle models and recurrence intervals of large earthquakes in the Algiers area.

  17. Infliximab Versus Conventional Combination Treatment and Seven-Year Work Loss in Early Rheumatoid Arthritis: Results of a Randomized Swedish Trial.

    Science.gov (United States)

    Eriksson, Jonas K; Wallman, Johan K; Miller, Heather; Petersson, Ingemar F; Ernestam, Sofia; Vivar, Nancy; van Vollenhoven, Ronald F; Neovius, Martin

    2016-12-01

    To compare long-term work loss in methotrexate-refractory early rheumatoid arthritis (RA) patients randomized to the addition of infliximab or conventional combination treatment. This study was a multicenter, 2-arm, parallel, randomized, active-controlled, open-label trial. RA patients with infliximab or conventional combination treatment with sulfasalazine plus hydroxychloroquine. Yearly sick leave and disability pension days >7 years after randomization were retrieved from nationwide registers kept by the Swedish Social Insurance Agency. Of 210 working-age patients, 109 were randomized to infliximab (mean age 48.4 years, 73% women) and 101 to conventional treatment (mean age 48.7 years, 77% women). The year before randomization, the mean number of annual work days lost was 127 in the infliximab arm and 118 in the conventional treatment group (mean difference 9 [95% confidence interval (95% CI) -23, 39]). Compared to the year before randomization, the mean changes at 7 years were -25 days in the infliximab and -26 days in the conventional treatment group (adjusted mean difference 10 [95% CI -25, 46]). The cumulative mean for work-loss days was 846 in the infliximab group and 701 in the conventional treatment group (adjusted mean difference 104 [95% CI -56, 284]). Long-term work loss improved significantly in early RA patients randomized to infliximab plus methotrexate or conventional combination therapy. No difference was detected between strategies, and the level of work-loss days remained twice that observed in the general population. © 2016, American College of Rheumatology.

  18. Seven years follow-up for total lumbar facet joint replacement (TOPS) in the management of lumbar spinal stenosis and degenerative spondylolisthesis.

    Science.gov (United States)

    Anekstein, Yoram; Floman, Yizhar; Smorgick, Yossi; Rand, Nahshon; Millgram, Michael; Mirovsky, Yigal

    2015-10-01

    To evaluate the feasibility and clinical improvement of a total posterior arthroplasty system in the surgical management of lumbar degenerative spondylolisthesis and or spinal stenosis. During a 1-year period (June 2006 to July 2007), ten patients were enrolled in a non-randomized prospective clinical study. The primary indication was neurogenic claudication due to spinal stenosis with single-level degenerative spondylolisthesis. Patients were evaluated with X-rays and MRI scans, visual analog scale (VAS) for back and leg pain, the Oswestry disability questionnaire, and the SF-36 health survey preoperatively, at 6 weeks, 3 months and 6 months and at 1, 2, 3 and 7 years postoperatively. The VAS score for back pain dropped from 56.2 preoperatively to 12.5 at 6 weeks and 19 at 7 years follow-up. The VAS score for worse leg pain dropped from 83.5 before surgery to 13 at 6 weeks and 8.8 at 7 years follow-up. The ODI dropped from 49.1 preoperatively to 13.5 at 6 weeks and 7.8 at 7 years follow-up. MRI examination at 7 years after surgery did not demonstrate stenosis adjacent to the stabilized segment. Spondylolisthesis did not progress in any of the cases. One patient had a symptomatic L3-L4 far lateral disc herniation 5 years after surgery whose symptoms resolved with non-operative treatment. In one patient, conversion to posterolateral fusion was performed due to an early device malfunction. In patients with spinal stenosis and degenerative spondylolisthesis, decompression and posterior arthroplasty with the TOPS System can maintain clinical improvement and radiologic stability over time.

  19. Decline of Neurologic Varicella Complications in Children During the First Seven Years After Introduction of Universal Varicella Vaccination in Germany, 2005-2011.

    Science.gov (United States)

    Streng, Andrea; Grote, Veit; Rack-Hoch, Anita; Liese, Johannes G

    2017-01-01

    Universal varicella vaccination for 1-year-old children was introduced in Germany in 2004. We investigated changes in the incidence and type of varicella-associated neurologic complications in children during the first 7 years after universal vaccination recommendation. A surveillance study was conducted based on patients linear trend across years was assessed by Poisson regression models. Of a total of 1263 varicella-associated pediatric hospitalizations, 228 children (18.1%) had neurologic complications (median age 4 years, interquartile range 2-7; 56% male). The most frequent neurologic complications were febrile convulsion (32.0% of 228 children, median age 3.0 years), varicella encephalitis or meningitis (28.9%; median age 4.5 years), syncope (13.2%; median age 7.0 years) and cerebral convulsion (11.0%; median age 4.0 years). Other complications included ataxia (3.1%), facial nerve palsy (2.6%) and cerebral vasculitis/infarction (1.8%). Neurologic complications showed a continuous decrease between 2005 and 2011, from an incidence of 2.8 (95% confidence interval: 2.1-3.6) per 100,000 children <17 years of age to 1.2 (95% confidence interval: 0.7-2.1; P < 0.001). In particular, a marked decline was observed among children up to 7 years of age, mainly because of a decrease in the number of febrile convulsions and encephalitis or meningitis. The incidence of varicella-associated neurologic complications in children decreased approximately by 60% during the first 7 years following the recommendation for universal vaccination.

  20. Can pre-operative axial CT imaging predict syndesmosis instability in patients sustaining ankle fractures? Seven years' experience in a tertiary trauma center

    Energy Technology Data Exchange (ETDEWEB)

    Yeung, Tsz Wai; Chan, Chung Yan Grace; Chan, Wun Cheung Samuel; Yuen, Ming Keung [Tuen Mun Hospital, Department of Radiology, Tuen Mun (China); Yeung, Yuk Nam [Tune Mun Hospital, Department of Orthopaedics and Traumatology, Tuen Mun (China)

    2015-06-01

    The purpose of this study is to explore the diagnostic accuracy of CT measurements in predicting syndesmosis instability of injured ankle, with correlation to operative findings. From July 2006 to June 2013, 123 patients presented to a single tertiary hospital who received pre-operative CT for ankle fractures were retrospectively reviewed. All patients underwent open reduction and internal fixation for fractures and intra-operative syndesmosis integrity tests. The morphology of incisura fibularis was categorized as deep or shallow. The tibiofibular distance (TFD) between the medial border of the fibula and the nearest point of the lateral border of tibia were measured at anterior (aTFD), middle (mTFD), posterior (pTFD), and maximal (maxTFD) portions across the syndesmosis on axial CT images at 10 mm proximal to the tibial plafond. Statistical analysis was performed with independent samples t test and ROC curve analysis. Intraobserver reproducibility and inter-observers agreement were also evaluated. Of the 123 patients, 39 (31.7 %) were operatively diagnosed with syndesmosis instability. No significant difference of incisura fibularis morphology (deep or shallow) and TFDs was demonstrated respective to genders. The axial CT measurements were significantly higher in ankles diagnosed with syndesmosis instability than the group without (maxTFD means 7.2 ± 2.96 mm vs. 4.6 ± 1.4 mm, aTFD mean 4.9 ± 3.7 mm vs. 1.8 ± 1.4 mm, mTFD mean 5.3 ± 2.4 mm vs. 3.2 ± 1.6 mm, pTFD mean 5.3 ± 1.8 mm vs. 4.1 ± 1.3 mm, p < 0.05). Their respective cutoff values with best sensitivity and specificity were calculated; the aTFD (AUC 0.798) and maxTFD (AUC 0.794) achieved the highest diagnostic accuracy. The optimal cutoff levels were aTFD = 4 mm (sensitivity, 56.4 %; specificity, 91.7 %) and maxTFD = 5.65 mm (sensitivity, 74.4 %; specificity, 79.8 %). The inter-observer agreement was good for all aTFD, mTFD, pTFD, and maxTFD measurements (ICC 0.959, 0.799, 0.783, and 0.865). The ICC

  1. Blue Ribbon Panel Report

    Science.gov (United States)

    An NCI Cancer Currents blog by the NCI acting director thanking the cancer community for contributing to the Cancer Moonshot Blue Ribbon Panel report, which was presented to the National Cancer Advisory Board on September 7.

  2. Autoimmune liver disease panel

    Science.gov (United States)

    Liver disease test panel - autoimmune ... Autoimmune disorders are a possible cause of liver disease. The most common of these diseases are autoimmune hepatitis and primary biliary cholangitis (formerly called primary biliary cirrhosis). This group of tests ...

  3. Basic metabolic panel

    Science.gov (United States)

    ... Alternative Names SMAC7; Sequential multi-channel analysis with computer-7; SMA7; Metabolic panel 7; CHEM-7 References ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  4. REINFORCED COMPOSITE PANEL

    DEFF Research Database (Denmark)

    2003-01-01

    A composite panel having front and back faces, the panel comprising facing reinforcement, backing reinforcement and matrix material binding to the facing and backing reinforcements, the facing and backing reinforcements each independently comprising one or more reinforcing sheets, the facing...... reinforcement being located on or embedded in matrix material adjacent to the front face of the panel, the backing reinforcement being located in a plane or planes substantially parallel to the plane or planes of the facing reinforcement, and being substantially coextensive therewith, and spaced therefrom...... by matrix material, the facing and backing reinforcements being interconnected to resist out-of-plane relative movement. The reinforced composite panel is useful as a barrier element for shielding structures, equipment and personnel from blast and/or ballistic impact damage....

  5. Hexagon solar power panel

    Science.gov (United States)

    Rubin, I. (Inventor)

    1978-01-01

    A solar energy panel support is described upon which silicon cells are arrayed. The cells are wafer thin and of two geometrical types, both of the same area and electrical rating, namely hexagon cells and hourglass cells. The hourglass cells are composites of half hexagons. A near perfect nesting relationship of the cells achieves a high density packing whereby optimum energy production per panel area is achieved.

  6. Pop-Art Panels

    Science.gov (United States)

    Alford, Joanna

    2012-01-01

    James Rosenquist's giant Pop-art panels included realistic renderings of well-known contemporary foods and objects, juxtaposed with famous people in the news--largely from the 1960s, '70s and '80s--and really serve as visual time capsules. In this article, eighth-graders focus on the style of James Rosenquist to create their own Pop-art panel that…

  7. Equal Opportunities Advisory Panel

    CERN Multimedia

    HR Department

    2006-01-01

    At its meeting on 7 December 2006, the Standing Concertation Committee took note of the appointment of four new members of the Panel: Wisla Carena, Pierre Charrue, Sue Foffano and Markus Nordberg. The present composition of the Panel (appointed ad personam) is as follows: Tiziano Camporesi (Chairperson), Wisla Carena, Pierre Charrue, Sue Foffano, Josi Schinzel (Equal Opportunities Officer), Markus Nordberg, Christine Petit-Jean-Genaz et Elena Wildner. Human Resources Department Tel. 74480

  8. Hexagon solar power panel

    Science.gov (United States)

    Rubin, Irwin

    1978-01-01

    A solar energy panel comprises a support upon which silicon cells are arrayed. The cells are wafer thin and of two geometrical types, both of the same area and electrical rating, namely hexagon cells and hourglass cells. The hourglass cells are composites of half hexagons. A near perfect nesting relationship of the cells achieves a high density packing whereby optimum energy production per panel area is achieved.

  9. Solar energy heating panel

    Energy Technology Data Exchange (ETDEWEB)

    McMurtrie, T.

    1984-08-14

    A solar energy collecting and radiating panel for heating a fluid such as air circulating in an enclosure disposed behind the panel. The panel is in the form of a pan made of sheet metal, such as thin aluminum, darkened on its irradiated surface, the blackened or darkened surface being protected by a pane of glass. The panel has a plurality of dome-shaped dimples embossed on and projecting from its irradiated surface such as to present a large surface area to exposure to sun rays and to capture solar energy independently of the sun height or position relative to the horizon. The heat absorbed by the panel is conveyed by its back surface to air circulating by convection or by forced circulation in a thermally insulated enclosure, for heating a building or for any other utilization. A plurality of panels may be disposed side by side to form a solar energy collecting array preferably mounted on an outside wall of a building, in a southerly orientation.

  10. A nationwide multicentre study in Turkey for establishing reference intervals of haematological parameters with novel use of a panel of whole blood

    Science.gov (United States)

    Ozarda, Yesim; Ichihara, Kiyoshi; Bakan, Ebubekir; Polat, Harun; Ozturk, Nurinnisa; Baygutalp, Nurcan K.; Taneli, Fatma; Guvenc, Yesim; Ormen, Murat; Erbayraktar, Zubeyde; Aksoy, Nurten; Sezen, Hatice; Demir, Meltem; Eskandari, Gulcin; Polat, Gurbuz; Mete, Nuriye; Yuksel, Hatice; Vatansev, Husamettin; Gun, Fatma; Akin, Okhan; Ceylan, Ozlem; Noyan, Tevfik; Gozlukaya, Ozgul; Aliyazicioglu, Yuksel; Kahraman, Sevim; Dirican, Melahat; Tuncer, Gul Ozlem; Kimura, Shogo; Eker, Pinar

    2017-01-01

    Introduction A nationwide multicentre study was conducted to establish well-defined reference intervals (RIs) of haematological parameters for the Turkish population in consideration of sources of variation in reference values (RVs). Materials and methods K2-EDTA whole blood samples (total of 3363) were collected from 12 laboratories. Sera were also collected for measurements of iron, UIBC, TIBC, and ferritin for use in the latent abnormal values exclusion (LAVE) method. The blood samples were analysed within 2 hours in each laboratory using Cell Dyn and Ruby (Abbott), LH780 (Beckman Coulter), or XT-2000i (Sysmex). A panel of freshly prepared blood from 40 healthy volunteers was measured in common to assess any analyser-dependent bias in the measurements. The SD ratio (SDR) based on ANOVA was used to judge the need for partitioning RVs. RIs were computed by the parametric method with/without applying the LAVE method. Results Analyser-dependent bias was found for basophils (Bas), MCHC, RDW and MPV from the panel test results and thus those RIs were derived for each manufacturer. RIs were determined from all volunteers’ results for WBC, neutrophils, lymphocytes, monocytes, eosinophils, MCV, MCH and platelets. Gender-specific RIs were required for RBC, haemoglobin, haematocrit, iron, UIBC and ferritin. Region-specific RIs were required for RBC, haemoglobin, haematocrit, UIBC, and TIBC. Conclusions With the novel use of a freshly prepared blood panel, manufacturer-specific RIs’ were derived for Bas, Bas%, MCHC, RDW and MPV. Regional differences in RIs were observed among the 7 regions of Turkey, which may be attributed to nutritional or environmental factors, including altitude. PMID:28694726

  11. Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study

    Directory of Open Access Journals (Sweden)

    Yolanda Vidal Insua

    2017-06-01

    Full Text Available Colorectal cancer (CRC is one of the major causes of cancer-related deaths. Early detection of tumor relapse is crucial for determining the most appropriate therapeutic management. In clinical practice, computed tomography (CT is routinely used, but small tumor changes are difficult to visualize, and reliable blood-based prognostic and monitoring biomarkers are urgently needed. The aim of this study was to prospectively validate a gene expression panel (composed of GAPDH, VIL1, CLU, TIMP1, TLN1, LOXL3 and ZEB2 for detecting circulating tumor cells (CTCs as prognostic and predictive tool in blood samples from 94 metastatic CRC (mCRC patients. Patients with higher gene panel expression before treatment had a reduced progression-free survival (PFS and overall-survival (OS rates compared with patients with low expression (p = 0.003 and p ≤ 0.001, respectively. Patients with increased expression of CTCs markers during treatment presented PFS and OS times of 8.95 and 11.74 months, respectively, compared with 14.41 and 24.7 for patients presenting decreased expression (PFS; p = 0.020; OS; p ≤ 0.001. Patients classified as non-responders by CTCs with treatment, but classified as responders by CT scan, showed significantly shorter survival times (PFS: 8.53 vs. 11.70; OS: 10.37 vs. 24.13; months. In conclusion, our CTCs detection panel demonstrated efficacy for early treatment response assessment in mCRC patients, and with increased reliability compared to CT scan.

  12. [Social Determinants of Subjective Health, Life Satisfaction and Absence From School due to Illness Among Adolescents: First results of the German National Educational Panel Study (NEPS)].

    Science.gov (United States)

    Heilmann, Kristina; Bräsen, Janina; Herke, Max; Richter, Matthias; Rathmann, Katharina

    2017-02-16

    The aim of this study is to examine the impact of social determinants on subjective health, life satisfaction and absence from school due to illness among adolescents in secondary schools, by using data from the German National Educational Panel Study (NEPS). Data was obtained from the National Educational Panel Study (NEPS). The sample included (n=5 790) 6 th grade pupils in regular schools in 2011 (Starting Cohort 3, Wave 2). The socioeconomic background of adolescents was measured by pupils' school type as well as household income and parental education level. Family structure and gender were considered as additional social determinants in the analyses. Bivariate and multiple logistic regression techniques were applied. The results show that type of school and low household income were related to poor subjective health among students. Life satisfaction varied by family structure and school type. For absence from school due to illness, we found a weak association with students in low track schools. The results indicate that especially the school type had the most important impact on subjective health, life satisfaction and absence from school due to illness. Health promotion and preventive strategies should particularly focus on pupils in low track schools and in relation to socially unequal distribution of educational opportunities also on young people from households with low socioeconomic status. © Georg Thieme Verlag KG Stuttgart · New York.

  13. Panel and planar experimental shear behavior of wood panels ...

    African Journals Online (AJOL)

    Panel and planar experimental shear behavior of wood panels laminated softwood oriented OSB conditioned at different environments. ... to that measured in the case of panel shear for different environments. Keywords : oriented strand board – panel shear strength- planar shear strength - environment – moisture content ...

  14. Panel cutting method: new approach to generate panels on a hull in Rankine source potential approximation

    Directory of Open Access Journals (Sweden)

    Hee-Jong Choi

    2011-12-01

    Full Text Available In the present study, a new hull panel generation algorithm, namely panel cutting method, was developed to predict flow phenomena around a ship using the Rankine source potential based panel method, where the iterative method was used to satisfy the nonlinear free surface condition and the trim and sinkage of the ship was taken into account. Numerical computations were performed to investigate the validity of the proposed hull panel generation algorithm for Series 60 (CB=0.60 hull and KRISO container ship (KCS, a container ship designed by Maritime and Ocean Engineering Research Institute (MOERI. The computational results were validated by comparing with the existing experimental data.

  15. Experimental Study of Stress-Strain Behaviour of Open-Cell Aluminium Foam Sandwich Panel for Automotive Structural Part

    Directory of Open Access Journals (Sweden)

    Nur Asmawiyah Ibrahim

    2017-07-01

    Full Text Available Because of high stiffness and strength to weight ratio, aluminium foam sandwich (AFS has huge advantage in automotive industries in order to reduce the vehicle’s weight which consequently will reduce the fuel consumption. While reducing the weight, AFS must also maintain high strength and durability compared to other competitive materials used which perform same functionalities. AFS had been proved its suitability for industrial application by previous researchers such as in aerospace, automotive and architecture. However, there is still a gap need to be filled in order to expand the use of the AFS in another application. In this paper, the tensile strength of AFS panel made of from aluminium skin sheets and open-cell aluminium foam core with various thickness is investigated. Design of experiment was developed according to JUMP (JMP statistical software and experimental work was done using universal testing machine. The stress-strain behavior was analysed. The result shows that the effect of skin to core ratio is significant on the stress-strain behavior.

  16. The role of appearance schematicity in the internalization of media appearance ideals: A panel study of preadolescents.

    Science.gov (United States)

    Rousseau, Ann; Gamble, Hilary; Eggermont, Steven

    2017-10-01

    Individuals who are more strongly invested in their appearance, appearance schematics, have a tendency to engage in appearance-related comparison. Appearance schematicity consists of two components. The self-evaluative component concerns the degree to which appearance is central to self-worth, referred to as dysfunctional appearance beliefs. Motivational salience refers to the engagement in behaviors designed to enhance appearance, such as body surveillance. Based on a three-wave panel survey of 973 Flemish preadolescents (M age  = 11.15, SD = 1.13) we found that the motivational and self-evaluative components had a different impact on media internalization. For preadolescents who engaged in more body surveillance, watching television resulted in more media internalization. For preadolescents who had fewer dysfunctional appearance beliefs, watching television resulted in more media internalization. These findings suggest that appearance schematicity is an important susceptibility variable in the relationship between TV-exposure and media internalization, and emphasize the importance of investigating individual dispositions beyond gender differences. Copyright © 2017 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  17. Streamlining CubeSat Solar Panel Fabrication Processes

    OpenAIRE

    Sandberg, Ariel; Smith, Timothy

    2016-01-01

    A critical facet of CubeSat fabrication is solar panel characterization and assembly. Though capable of producing flight quality solar subsystems, traditional methods of solar panel fabrication contain intrinsic inefficiencies and inconsistencies that compromise the subsystem’s overall reliability. Taking Michigan Exploration Laboratory’s (MXL) heritage solar panel procedures as a case study, this investigation sought to streamline the solar panel fabrication process to increase its yield, co...

  18. Low velocity impact behaviour of ultra high strength concrete panels

    Indian Academy of Sciences (India)

    oped to simulate the impact behaviour of UHSC panel. The Brittle cracking model is used to simulate the behaviour of UHSC panel under impact loading and to perform parametric studies by varying the volume fraction of steel fibres. Keywords. Ultra high strength concrete; panel; drop weight test; impact analysis;. ABAQUS.

  19. Efficiency of geometric designs of flexible solar panels: mathematical simulation

    Science.gov (United States)

    Marciniak, Malgorzata; Hassebo, Yasser; Enriquez-Torres, Delfino; Serey-Roman, Maria Ignacia

    2017-09-01

    The purpose of this study is to analyze various surfaces of flexible solar panels and compare them to the traditional at panels mathematically. We evaluated the efficiency based on the integral formulas that involve flux. We performed calculations for flat panels with different positions, a cylindrical panel, conical panels with various opening angles and segments of a spherical panel. Our results indicate that the best efficiency per unit area belongs to particular segments of spherically-shaped panels. In addition, we calculated the optimal opening angle of a cone-shaped panel that maximizes the annual accumulation of the sun radiation per unit area. The considered shapes are presented below with a suggestion for connections of the cells.

  20. The method of neutron imaging as a tool for the study of the dynamics of water movement in wet aramid-based ballistic body armour panels

    Science.gov (United States)

    Reifler, Felix A.; Lehmann, Eberhard H.; Frei, Gabriel; May, Hans; Rossi, René

    2006-07-01

    A new non-destructive method based on neutron imaging (neutron radiography) to determine the exact water content in aramid-based soft body armour panels is presented. While investigating the ballistic resistance of aramid-based body armour panels under a wet condition, it is important to precisely determine their water content and its chronological development. Using the presented method, the influence of water amount and location on impact testing as well as its time dependence was shown. In the ballistic panels used, spreading of water strongly depended on the kind of quilting. Very fast water migration could be observed when the panels were held vertically. Some first results regarding the water distribution in wet panels immediately after the impact are presented. On the basis of the presented results, requirements for a standard for testing the performance of ballistic panels in the wet state are deduced.

  1. Fatigue as a manifestation of psychosocial distress in a low-income country: a population-based panel study.

    Science.gov (United States)

    Smartt, Caroline; Medhin, Girmay; Alem, Atalay; Patel, Vikram; Dewey, Michael; Prince, Martin; Hanlon, Charlotte

    2016-03-01

    Fatigue is a common complaint worldwide and associated with disability and high health service use costs. We tested the hypothesis that maternal fatigue would be associated independently with maternal common mental disorder ('maternal CMD') in a rural, low-income country setting. The analysis was conducted using data from a population-based cohort located in the Butajira demographic surveillance site, Ethiopia. A total of 1065 women were recruited in pregnancy and followed up to 2.5 (n = 1009; 94.7%) and 3.5 years post-partum (n = 989; 92.9%). Maternal CMD symptoms were measured using a locally validated version of the Self-Reporting Questionnaire and fatigue was measured using a dichotomised item from the Patient Health Questionnaire-15. Physical health indicators included haemoglobin level, body mass index and illness episodes. Generalised estimating equations were used to conduct hypothesis-driven and exploratory multivariable analyses in the panel at 2.5 and 3.5 years. The prevalence of maternal fatigue was 8.3% at 2.5 years and 5.5% at 3.5 years post-partum. Psychological symptoms of maternal CMD were associated independently with complaints of fatigue after adjusting for anaemia, body mass index, physical ill health, poverty and other confounding variables: adjusted odds ratio (aOR), 1.46; 95% confidence interval (CI), 1.28-1.66 for each one point increase in SRQ score. In the multivariable model, only psychosocial factors (CMD and stressful life events) and self-reported physical ill health were associated significantly with complaints of fatigue. Complaints of fatigue are associated strongly with maternal CMD and other psychosocial risk factors in this rural, low-income country setting with a high burden of undernutrition and infectious disease. Fatigue should be understood as a potential indicator of CMD in primary care to improve detection and treatment. © 2015 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd.

  2. Detecting moisture in composite honeycomb panels

    Science.gov (United States)

    Culp, J. D.; Sapp, J. W., Jr.

    1979-01-01

    Radiographic inspection technique detects liquids trapped in cells of honeycomb composite panels constructed with porous fiber-reinforced plastic skins. Procedure is of use in industries such as aerospace or automotive engineering where honeycomb composites are being used or studied.

  3. Codominant scoring of AFLP in association panels

    NARCIS (Netherlands)

    Gort, G.; Eeuwijk, van F.A.

    2010-01-01

    A study on the codominant scoring of AFLP markers in association panels without prior knowledge on genotype probabilities is described. Bands are scored codominantly by fitting normal mixture models to band intensities, illustrating and optimizing existing methodology, which employs the

  4. Predicting panel scores by linguistic analysis

    Energy Technology Data Exchange (ETDEWEB)

    Van den Besselaar, P.; Stout, L.; Gou, X

    2016-07-01

    In this paper we explore the use of text analysis for deriving quality indicators of project proposals. We do full text analysis of 3030 review reports. After term extraction, we aggregate the term occurrences to linguistic categories. Using thse linguistic categories as independent variables, we study how well these predict the grading by the review panels. Together, the different linguistic categories explain about 50% of the variance in the grading of the applications. The relative importance of the different linguistic categories inform us about the way the panels work. This can be used to develop altmetrics for the quality of the peer and panel review processes. (Author)

  5. Structural Analysis of Sandwich Foam Panels

    Energy Technology Data Exchange (ETDEWEB)

    Kosny, Jan [ORNL; Huo, X. Sharon [Tennessee Technological University

    2010-04-01

    The Sandwich Panel Technologies including Structural Insulated Panels (SIPs) can be used to replace the conventional wooden-frame construction method. The main purpose of this Cooperative Research and Development Agreement (CRADA) between UT-Battelle, LLC and SGI Venture, Inc. was to design a novel high R-value type of metal sandwich panelized technology. This CRADA project report presents design concept discussion and numerical analysis results from thermal performance study of this new building envelope system. The main objective of this work was to develop a basic concept of a new generation of wall panel technologies which will have R-value over R-20 will use thermal mass to improve energy performance in cooling dominated climates and will be 100% termite resistant. The main advantages of using sandwich panels are as follows: (1) better energy saving structural panels with high and uniform overall wall R-value across the elevation that could not be achieved in traditional walls; and (2) reducing the use of raw materials or need for virgin lumber. For better utilization of these Sandwich panels, engineers need to have a thorough understanding of the actual performance of the panels and system. Detailed analysis and study on the capacities and deformation of individual panels and its assembly have to be performed to achieve that goal. The major project activity was to conduct structural analysis of the stresses, strains, load capacities, and deformations of individual sandwich components under various load cases. The analysis simulated the actual loading conditions of the regular residential building and used actual material properties of the steel facings and foam.

  6. Panel 3 - characterization

    Energy Technology Data Exchange (ETDEWEB)

    Erck, R.A.; Erdemir, A.; Janghsing Hsieh; Lee, R.H.; Xian Zheng Pan; Deming Shu [Argonne National Lab., IL (United States); Feldman, A. [National Inst. of Standards and Technology, Gaithersburg, MD (United States); Glass, J.T. [North Carolina State Univ., Raleigh (United States); Kleimer, R. [Coors Ceramics Co., Golden, CO (United States); Lawton, E.A. [JPL/Caltech, Pasadena, CA (United States); McHargue, C.J. [Univ. of Tennessee, Knoxville (United States)

    1993-01-01

    The task of this panel was to identify and prioritize needs in the area of characterization of diamond and diamond-like-carbon (DLC) films for use in the transportation industry. Until recent advances in production of inexpensive films of diamonds and DLC, it was not feasible that these materials could be mass produced. The Characterization Panel is restricting itself to identifying needs in areas that would be most useful to manufacturers and users in producing and utilizing diamond and DLC coatings in industry. These characterization needs include in-situ monitoring during growth, relation of structure to performance, and standards and definitions.

  7. Relationship between Mobile Phone Addiction and the Incidence of Poor and Short Sleep among Korean Adolescents: a Longitudinal Study of the Korean Children & Youth Panel Survey.

    Science.gov (United States)

    Lee, Joo Eun; Jang, Sung In; Ju, Yeong Jun; Kim, Woorim; Lee, Hyo Jung; Park, Eun Cheol

    2017-07-01

    Three of ten teenagers in Korea are addicted to mobile phones. The aim of this study was to examine the relationship between mobile phone addiction and the incidence of poor sleep quality and short sleep duration in adolescents. We used longitudinal data from the Korean Children & Youth Panel Survey conducted by the National Youth Policy Institute in Korea (2011-2013). A total of 1,125 students at baseline were included in this study after excluding those who already had poor sleep quality or short sleep duration in the previous year. A generalized estimating equation was used to analyze the data. High mobile phone addiction (mobile phone addiction score > 20) increased the risk of poor sleep quality but not short sleep duration. We suggest that consistent monitoring and effective intervention programs are required to prevent mobile phone addiction and improve adolescents' sleep quality. © 2017 The Korean Academy of Medical Sciences.

  8. Relationship between Mobile Phone Addiction and the Incidence of Poor and Short Sleep among Korean Adolescents: a Longitudinal Study of the Korean Children & Youth Panel Survey

    Science.gov (United States)

    2017-01-01

    Three of ten teenagers in Korea are addicted to mobile phones. The aim of this study was to examine the relationship between mobile phone addiction and the incidence of poor sleep quality and short sleep duration in adolescents. We used longitudinal data from the Korean Children & Youth Panel Survey conducted by the National Youth Policy Institute in Korea (2011–2013). A total of 1,125 students at baseline were included in this study after excluding those who already had poor sleep quality or short sleep duration in the previous year. A generalized estimating equation was used to analyze the data. High mobile phone addiction (mobile phone addiction score > 20) increased the risk of poor sleep quality but not short sleep duration. We suggest that consistent monitoring and effective intervention programs are required to prevent mobile phone addiction and improve adolescents' sleep quality. PMID:28581275

  9. [Class Climate, Academic Well-Being and Self-Rated Health Among School Children in Germany: Findings of the National Educational Panel Study (NEPS)].

    Science.gov (United States)

    Rathmann, Katharina; Herke, Max; Hurrelmann, Klaus; Richter, Matthias

    2018-04-01

    The aim of this study was to examine the associations between features of class climate and school wellbeing, based on self-rated health and reports of absence from school due to illness among adolescents in secondary schools, by using data from the German National Educational Panel Study (NEPS). Data was obtained from the National Educational Panel Study (NEPS). The sample includes (n=7,348) seventh grade students in regular schools (Starting Cohort 3, Wave 3, 2012). Measures of class climate comprise indicators about demands, control and orientation, autonomy and interaction among students as well as teaching quality in German language class. School wellbeing was measured by satisfaction with school and helplessness in main school subjects. Bivariate and logistic multilevel logistic regression techniques are applied, by controlling for student age, gender and school type attended. Multilevel results showed that particularly among students with higher school satisfaction, there was a higher likelihood of self-rated health and less school absence due to illness. In contrast, perceived helplessness in major subjects and learning orientation were negatively associated with both outcomes. Further, students attending low track schools had a higher risk of school absence than students in high track schools. The results highlight the fact that particularly students' school wellbeing in terms of school satisfaction and perceived helplessness in the subjects German and mathematics are associated with self-rated poorer health and school absence due to illness. Therefore, health promotion initiatives should particularly focus on students' school wellbeing as well as on students attending low track schools. © Georg Thieme Verlag KG Stuttgart · New York.

  10. Penentuan Nilai Penyerapan Suara Pada Panel Dinding Beton Busa Sebagai Panel Alternatif Yang Ramah Lingkungan

    Directory of Open Access Journals (Sweden)

    Zulfian Zulfian

    2011-06-01

    Full Text Available Panel of foam concrete wall is a type of membrane panel which has maximum sound absorption and can create quite and environmentally friendly room. The purpose of this study was to determine the magnitudeof the sound absorption value using the Sabine formula in Reverberation Chamber at Syiah Kuala University acoustic laboratory. The result of this study show that peak value curve sound absorption of 0.67 accurs at the frequency of 250 Hz, and painting of the panel surface can increase the value of sound absorption to be 0.76 at the frequency of 250 Hz,but the slope of sound absorption value sharply decreased to be 0.07at the frequency of 1000 Hz. Treatment on the panel surface can increase or decrease the value of sound absorption especially at the low frequency regions. Keywords: Panel of foam concrete wall, Sabine formula, The value of sound absorption

  11. Robust estimation procedure in panel data model

    Energy Technology Data Exchange (ETDEWEB)

    Shariff, Nurul Sima Mohamad [Faculty of Science of Technology, Universiti Sains Islam Malaysia (USIM), 71800, Nilai, Negeri Sembilan (Malaysia); Hamzah, Nor Aishah [Institute of Mathematical Sciences, Universiti Malaya, 50630, Kuala Lumpur (Malaysia)

    2014-06-19

    The panel data modeling has received a great attention in econometric research recently. This is due to the availability of data sources and the interest to study cross sections of individuals observed over time. However, the problems may arise in modeling the panel in the presence of cross sectional dependence and outliers. Even though there are few methods that take into consideration the presence of cross sectional dependence in the panel, the methods may provide inconsistent parameter estimates and inferences when outliers occur in the panel. As such, an alternative method that is robust to outliers and cross sectional dependence is introduced in this paper. The properties and construction of the confidence interval for the parameter estimates are also considered in this paper. The robustness of the procedure is investigated and comparisons are made to the existing method via simulation studies. Our results have shown that robust approach is able to produce an accurate and reliable parameter estimates under the condition considered.

  12. Advanced Solar Panel Designs

    Science.gov (United States)

    Ralph, E. L.; Linder, E. B.

    1995-01-01

    Solar panel designs that utilize new high-efficiency solar cells and lightweight rigid panel technologies are described. The resulting designs increase the specific power (W/kg) achievable in the near-term and are well suited to meet the demands of higher performance small satellites (smallsats). Advanced solar panel designs have been developed and demonstrated on two NASA SBIR contracts at Applied Solar. The first used 19% efficient, large area (5.5 cm x 6.5 cm) GaAs/Ge solar cells with a lightweight rigid graphite epoxy isogrid substrate configuration. A 1,445 sq cm coupon was fabricated and tested to demonstrate 60 W/kg with a high potential of achieving 80 W/kg. The second panel design used new 22% efficiency, dual-junction GaInP2/GaAs/Ge solar cells combined with a lightweight aluminum core/graphite fiber mesh facesheet substrate. A 1,445 sq cm coupon was fabricated and tested to demonstrate 105 W/kg with the potential of achieving 115 W/kg.

  13. Photovoltaic-Panel Laminator

    Science.gov (United States)

    Keenan, R.

    1985-01-01

    Two-piece unit heats and presses protective layers to form laminate. Rubber diaphragm between upper and lower vacuum chambers alternates between neutral position and one that presses against solar-cell array, supplying distributed force necessary to press layers of laminate together. Encapsulation helps to protect cells from environment and to ensure long panel life while allowing efficient generation of electricity from Sunlight.

  14. Dynamic panel data models

    NARCIS (Netherlands)

    Bun, M.J.G.; Sarafidis, V.

    2013-01-01

    This Chapter reviews the recent literature on dynamic panel data models with a short time span and a large cross-section. Throughout the discussion we considerlinear models with additional endogenous covariates. First we give a broad overview of available inference methods placing emphasis on GMM.

  15. Student Panels, Business Administration

    DEFF Research Database (Denmark)

    Rask, Morten

    of MSc programmes, the MSc coordinator as well as the administrative secretary. A student panel meets with the department twice in the first year: Early in February to sum up experience from the first semester and in early in June to sum up experience from the second semester. At semester start each MSc...

  16. A Cross-Lag Panel Analysis of Low Self-Esteem as a Predictor of Adolescent Internalizing Symptoms in a Prospective Longitudinal Study.

    Science.gov (United States)

    In-Albon, Tina; Meyer, Andrea H; Metzke, Christa Winkler; Steinhausen, Hans-Christoph

    2017-06-01

    Self-esteem, generally regarded as an important indicator of adolescents' mental health, was assessed by a self-report questionnaire in a school sample of 593 subjects who had been assessed at 3 time points over 7 years between 11 and 25 years of age within the Zurich Psychology and Psychopathology Study (ZAPPS). Cross-lagged panel analyses of the longitudinal data from ZAPPS indicated that self-esteem was predictive of internalizing problems and had an impact on internalizing symptoms when the analyses were adjusted for coping behavior, efficiency of social networks, and impact of stressful life events. Self-esteem was also stable (r = .37-.60) within the observed age range, after controlling for prior levels of the predicted variables. The findings support the impact of self-esteem on mental health and indicate the importance of addressing self-esteem in prevention and intervention programs.

  17. The TVT Glass Pavilion: Theoretical Study on a Highly Transparent Building Made with Long-Spanned TVT Portals Braced with Hybrid Glass-Steel Panels

    Directory of Open Access Journals (Sweden)

    Maurizio Froli

    2017-06-01

    Full Text Available In contemporary buildings, the architectural demand for a complete dematerialisation of load bearing structures can be satisfied only in limited cases with the exclusive structural use of glass. Otherwise, for challenging applications such as long spanned or high-rise structures, the use of hybrid glass-steel systems is mandatory. Glass, fragile but highly compressive resistant, is associated with steel, ductile and tensile resistant. The present research shows the feasibility study for a fully glazed pavilion made of six TVT (Travi Vitree Tensegrity portal frames longitudinally braced by pre-stressed hybrid glass panels. The frames are about 20 m in span and 8 m in height. Appropriate multiscalar FEM numerical analyses, calibrated on the collapse tests performed on previous TVT large-scale prototypes, stated that the structural performance would be able to withstand heavy static and dynamic loads and stated the observance of the Fail-Safe Design principles.

  18. Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients.

    Science.gov (United States)

    Kim, Seung Tae; Lee, Won-Suk; Lanman, Richard B; Mortimer, Stefanie; Zill, Oliver A; Kim, Kyoung-Mee; Jang, Kee Taek; Kim, Seok-Hyung; Park, Se Hoon; Park, Joon Oh; Park, Young Suk; Lim, Ho Yeong; Eltoukhy, Helmy; Kang, Won Ki; Lee, Woo Yong; Kim, Hee-Cheol; Park, Keunchil; Lee, Jeeyun; Talasaz, AmirAli

    2015-11-24

    Sequencing of the mutant allele fraction of circulating cell-free DNA (cfDNA) derived from tumors is increasingly utilized to detect actionable genomic alterations in cancer. We conducted a prospective blinded study of a comprehensive cfDNA sequencing panel with 54 cancer genes. To evaluate the concordance between cfDNA and tumor DNA (tDNA), sequencing results were compared between cfDNA from plasma and genomic tumor DNA (tDNA). Utilizing next generation digital sequencing technology (DST), we profiled approximately 78,000 bases encoding 512 complete exons in the targeted genes in cfDNA from plasma. Seventy-five patients were prospectively enrolled between February 2013 and March 2014, including 61 metastatic cancer patients and 14 clinical stage II CRC patients with matched plasma and tissue samples. Using the 54-gene panel, we detected at least one somatic mutation in 44 of 61 tDNA (72.1%) and 29 of 44 (65.9%) cfDNA. The overall concordance rate of cfDNA to tDNA was 85.9%, when all detected mutations were considered. We collected serial cfDNAs during cetuximab-based treatment in 2 metastatic KRAS wild-type CRC patients, one with acquired resistance and one with primary resistance. We demonstrate newly emerged KRAS mutation in cfDNA 1.5 months before radiologic progression. Another patient had a newly emerged PIK3CA H1047R mutation on cfDNA analysis at progression during cetuximab/irinotecan chemotherapy with gradual increase in allele frequency from 0.8 to 2.1%. This blinded, prospective study of a cfDNA sequencing showed high concordance to tDNA suggesting that the DST approach may be used as a non-invasive biopsy-free alternative to conventional sequencing using tumor biopsy.

  19. The impact of round window vs cochleostomy surgical approaches on interscalar excursions in the cochlea: Preliminary results from a flat-panel computed tomography study

    Directory of Open Access Journals (Sweden)

    Nicole T. Jiam

    2016-09-01

    Full Text Available Objective: To evaluate incidence of interscalar excursions between round window (RW and cochleostomy approaches for cochlear implant (CI insertion. Methods: This was a retrospective case-comparison. Flat-panel CT (FPCT scans for 8 CI users with Med-El standard length electrode arrays were collected. Surgical technique was identified by a combination of operative notes and FPCT imaging. Four cochleae underwent round window insertion and 4 cochleae underwent cochleostomy approaches anterior and inferior to the round window. Results: In our pilot study, cochleostomy approaches were associated with a higher likelihood of interscalar excursion. Within the cochleostomy group, we found 29% of electrode contacts (14 of 48 electrodes to be outside the scala tympani. On the other hand, 8.5% of the electrode contacts (4 of 47 electrodes in the round window insertion group were extra-scalar to the scala tympani. These displacements occurred at a mean angle of occurrence of 364° ± 133°, near the apex of the cochlea. Round window electrode displacements tend to localize at angle of occurrences of 400° or greater. Cochleostomy electrodes occurred at an angle of occurrence of 19°–490°. Conclusions: Currently, the optimal surgical approach for standard CI electrode insertion is highly debated, to a certain extent due to a lack of post-operative assessment of intracochlear electrode contact. Based on our preliminary findings, cochleostomy approach is associated with an increased likelihood of interscalar excursions, and these findings should be further evaluated with future prospective studies. Keywords: Cochlear implantation, Round window insertion, Cochleostomy, Interscalar excursion, Electrode position, Flat-panel computed tomography, Surgical approach

  20. Panel data analysis of cardiotocograph (CTG) data.

    Science.gov (United States)

    Horio, Hiroyuki; Kikuchi, Hitomi; Ikeda, Tomoaki

    2013-01-01

    Panel data analysis is a statistical method, widely used in econometrics, which deals with two-dimensional panel data collected over time and over individuals. Cardiotocograph (CTG) which monitors fetal heart rate (FHR) using Doppler ultrasound and uterine contraction by strain gage is commonly used in intrapartum treatment of pregnant women. Although the relationship between FHR waveform pattern and the outcome such as umbilical blood gas data at delivery has long been analyzed, there exists no accumulated FHR patterns from large number of cases. As time-series economic fluctuations in econometrics such as consumption trend has been studied using panel data which consists of time-series and cross-sectional data, we tried to apply this method to CTG data. The panel data composed of a symbolized segment of FHR pattern can be easily handled, and a perinatologist can get the whole FHR pattern view from the microscopic level of time-series FHR data.

  1. The 2005 London terror attacks: An investigation of changes in psychological wellbeing and social capital pre- and post-attacks (2003-07)-A UK panel study.

    Science.gov (United States)

    Giordano, Giuseppe N; Lindström, Martin

    2016-12-01

    The London public transport suicide bombings, which occurred on 7th July 2005, were described as the worst single terrorist atrocity on British soil to date. Past acts of terrorism have been associated with deterioration in population mental health. They may also negatively impact levels of social capital, which is considered a buffer against poor mental health outcomes. By employing panel data from the British Household Panel Survey and following the same individuals (N T =9287) three times over a five-year period (2003, 2005 and 2007), the aim of this longitudinal multilevel study was to investigate: (i) the impact of terrorism on individual-level social capital (generalised trust and social participation) across the UK; and (ii) the buffering effects of social capital on psychological wellbeing (GHQ-12). By comparing 2005 and 2007 covariate values (including the two social capital proxies) against their pre-terror baseline (2003) measurements in two separate multilevel logistic regression models, we examined the immediate and longer-term effects of the 2005 attacks on our GHQ-12 outcome. Compared to baseline, generalised trust dropped from 44% to 36% immediately post-terror attacks in 2005, while local participation increased from 45.8% to 47.5%. Social capital levels started to return to baseline levels by 2007, yet both proxies maintained independent buffering effects against poor GHQ-12 scores in years 2005 and 2007. From this empirical evidence, it seems that though generalised trust levels are negatively affected by acts of terrorism, the accompanying increase in local active participation may aid in the re-establishment of societal norms and beliefs in later years. Decision makers should be aware that such atrocities may negatively impact on populations' generalised trust in the shorter-term. To safeguard against losing this buffer against poor mental health outcomes, local active participation should be encouraged.

  2. Detection of Cement Leakage After Vertebroplasty with a Non-Flat-Panel Angio Unit Compared to Multidetector Computed Tomography - An Ex Vivo Study

    International Nuclear Information System (INIS)

    Baumann, Clemens; Fuchs, Heiko; Westphalen, Kerstin; Hierholzer, Johannes

    2008-01-01

    The purpose of this study was to investigate the detection of cement leakages after vertebroplasty using angiographic computed tomography (ACT) in a non-flat-panel angio unit compared to multidetector computed tomography (MDCT). Vertebroplasty was performed in 19 of 33 cadaver vertebrae (23 thoracic and 10 lumbar segments). In the angio suite, ACT (190 o ; 1.5 o per image) was performed to obtain volumetric data. Another volumetric data set of the specimen was obtained by MDCT using a standard algorithm. Nine multiplanar reconstructions in standardized axial, coronal, and sagittal planes of every vertebra were generated from both data sets. Images were evaluated on the basis of a nominal scale with 18 criteria, comprising osseous properties (e.g., integrity of the end plate) and cement distribution (e.g., presence of intraspinal cement). MDCT images were regarded as gold standard and analyzed by two readers in a consensus mode. Rotational acquisitions were analyzed by six blinded readers. Results were correlated with the gold standard using Cohen's κ-coefficient analysis. Furthermore, interobserver variability was calculated. Correlation with the gold standard ranged from no correlation (osseous margins of the neuroforamen, κ = 0.008) to intermediate (trace of vertebroplasty canula; κ = 0.615) for criteria referring to osseous morphology. However, there was an excellent correlation for those criteria referring to cement distribution, with κ values ranging from 0.948 (paravertebral cement distribution) to 0.972 (intraspinal cement distribution). With a minimum of κ = 0.768 ('good correlation') and a maximum of κ = 0.91 ('excellent'), interobserver variability was low. In conclusion, ACT in an angio suite without a flat-panel detector depicts a cement leakage after vertebroplasty as well as MDCT. However, the method does not provide sufficient depiction of osseous morphology.

  3. LCD Panels: The Electronic Wonder.

    Science.gov (United States)

    Anderson, Glenn

    1994-01-01

    Describes Liquid Crystal Display (LCD) panels and their use in the classroom. Topics discussed include active versus passive matrix panels; the number of pixels; projectors, including transmissive or reflective overhead projectors; costs; and vendors that supply LCDs. (LRW)

  4. FEMA DFIRM Panel Scheme Polygons

    Data.gov (United States)

    Minnesota Department of Natural Resources — This layer contains information about the Flood Insurance Rate Map (FIRM) panel areas. The spatial entities representing FIRM panels are polygons. The polygon for...

  5. Mounting clips for panel installation

    Science.gov (United States)

    Cavieres, Andres; Al-Haddad, Tristan; Goodman, Joseph

    2017-07-11

    A photovoltaic panel mounting clip comprising a base, central indexing tabs, flanges, lateral indexing tabs, and vertical indexing tabs. The mounting clip removably attaches one or more panels to a beam or the like structure, both mechanically and electrically. It provides secure locking of the panels in all directions, while providing guidance in all directions for accurate installation of the panels to the beam or the like structure.

  6. Quality control of involved field radiotherapy in the HD 13 and HD 14 trials. Report of the radiotherapy panel of the German Hodgkin Study Group (GHSG)

    Energy Technology Data Exchange (ETDEWEB)

    Kriz, J.; Haverkamp, U.; Eich, H.T. [University of Muenster, Department of Radiation Oncology, Muenster (Germany); Baues, C. [University of Cologne, Department of Radiation Oncology, Cologne (Germany); Engenhart-Cabillic, R. [University of Marburg, Department of Radiation Oncology, Marburg (Germany); Herfarth, K. [University of Heidelberg, Department of Radiation Oncology, Heidelberg (Germany); Lukas, P. [University of Innsbruck, Department of Radiation Oncology, Innsbruck (Austria); Pluetschow, A.; Fuchs, M.; Engert, A. [University of Cologne, Department of Internal Medicine, Cologne (Germany); Schmidberger, H. [University of Mainz, Department of Radiation Oncology, Mainz (Germany); Staar, S. [Bremen Mitte, Department of Radiation Oncology, Bremen (Germany)

    2017-02-15

    As part of the foundation of the German Hodgkin Study Group (GHSG) in 1978, a central radiotherapy (RT) reference centre was established to evaluate and to improve the quality of treatment. During the study generations, the quality assurance programs (QAP) were continued and adapted to the demands of each study. The purpose of this article is to demonstrate the results of the fifth study generation and to compare them to the previous findings. With the start of the fourth GHSG study generation (HD10-12), a central prospective review of all diagnostic images was established to create an individual treatment plan for each early stage study patient. The quality of involved field RT was retrospectively evaluated by an expert panel of radiation oncologists. In the fifth study generation (HD13-15), the retrospective review of radiotherapy performed was refined and the results were compared with the findings of the fourth generation. The expert panel analyzed the RT planning and application of 1037 (28 %) patients (HD13 n = 465, HD14 n = 572). Simulation films were available in 85 % of cases and verification films in 87 %. RT was assessed as major violation in 46 % (HD13 = 38 %, HD14 = 52 %), minor violation in 9 % (HD13 = 9 %, HD14 = 9 %) and according to the protocol in 45 % (HD13 = 52 %, HD14 = 38 %). The value for QAP of RT within the GHSG trials is well known. Still there were several protocol violations. In the future, the QAP program has to be adapted to the requirements of ''modern RT'' in malignant lymphoma. (orig.) [German] Seit Gruendung der German Hodgkin Study Group (GHSG) im Jahr 1978 wurde ein zentrales Qualitaetssicherungsprogramm (QAP) der Radiotherapie (RT) etabliert, um die Qualitaet der RT sicherzustellen. Waehrend der fortlaufenden Studiengenerationen wurde dieses QAP kontinuierlich weiterentwickelt. In dieser Auswertung werden die Ergebnisse der fuenften Studiengeneration (HD13-15) praesentiert und mit frueheren Ergebnissen

  7. Experience with citizens panels

    International Nuclear Information System (INIS)

    Selwyn, J.

    2002-01-01

    In May 1999, 200 delegates attended a four-day UK Consensus Conference on radioactive waste management, which was organised by the UK Centre for Economic and Environmental Development (UK CEED) and supported by the government, industry and environmental groups. The event brought together a Citizens' Panel of fifteen people, randomly selected to represent a cross section of the British public, together with the major players in the debate. The four-day conference saw the panel cross-examine expert witnesses from organisations such as NIREX, British Nuclear Fuels Limited, the Ministry of Defence, Greenpeace and Friends of the Earth. The findings of their investigations were put together in a report containing detailed recommendations for government and industry and presented to the Minister on the final day. (author)

  8. Rational Design of Composite Panels

    DEFF Research Database (Denmark)

    Riber, Hans Jørgen

    1996-01-01

    panels as well as single-skin panels, the effect of shear is included. The finite difference method is used solving the system of governing plate equations. Laterally loaded panels are analysed with respect to mid-point deflections and stresses. The numerical results are discussed in the light of 'Det...

  9. Investigating the Effect of Academic Procrastination on the Frequency and Variety of Academic Misconduct: A Panel Study

    Science.gov (United States)

    Patrzek, Justine; Sattler, Sebastian; van Veen, Floris; Grunschel, Carola; Fries, Stefan

    2015-01-01

    In prior studies, academic procrastination has been discussed as an influencing factor of academic misconduct. However, empirical studies were conducted solely cross-sectionally and investigated only a few forms of academic misconduct. This large scale web-based study examined the responses of between 1359 and 2207 participants from different…

  10. How do retirement dynamics influence mental well-being in later life? A 10-year panel study

    NARCIS (Netherlands)

    Dingemans, E.; Henkens, K.

    2015-01-01

    Objectives Empirical studies have consistently shown the negative impact of involuntary retirement on mental well-being. However, few studies have thus far investigated the degree to which post-retirement work affects late-life outcomes. The present study improves our understanding of the impact of

  11. Changes in Ethnic Self-Identification and Heritage Language Preference in Adolescence : A Cross-Lagged Panel Study

    NARCIS (Netherlands)

    Geerlings, Jolien; Verkuijten, Maykel; Thijs, Jochem

    2015-01-01

    This study analyses data of the U.S. Children of Immigrants Longitudinal Study and focuses on the relations and changes in ethnic self-identification and preferred language use from early to late adolescence. The findings show that over time (pan-)ethnic self-identification increased and preference

  12. Panel data analysis using EViews

    CERN Document Server

    Agung, I Gusti Ngurah

    2013-01-01

    A comprehensive and accessible guide to panel data analysis using EViews software This book explores the use of EViews software in creating panel data analysis using appropriate empirical models and real datasets. Guidance is given on developing alternative descriptive statistical summaries for evaluation and providing policy analysis based on pool panel data. Various alternative models based on panel data are explored, including univariate general linear models, fixed effect models and causal models, and guidance on the advantages and disadvantages of each one is given. Panel Data Analysis

  13. Can I use a Panel? Panel Conditioning and Attrition Bias in Panel Surveys

    NARCIS (Netherlands)

    Das, J.W.M.; Toepoel, V.; van Soest, A.H.O.

    2007-01-01

    Over the past decades there has been an increasing use of panel surveys at the household or individual level, instead of using independent cross-sections. Panel data have important advantages, but there are also two potential drawbacks: attrition bias and panel conditioning effects. Attrition bias

  14. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

    DEFF Research Database (Denmark)

    de Vries, Paul S; Sabater-Lleal, Maria; Chasman, Daniel I

    2017-01-01

    of independent statistical tests using HapMap imputation, and 1000G imputation may lead to further independent tests that should be corrected for. When using a stricter Bonferroni correction for the 1000G GWA study (P-value

  15. Flat panel detector-based cone beam computed tomography with a circle-plus-two-arcs data acquisition orbit: Preliminary phantom study

    International Nuclear Information System (INIS)

    Ning Ruola; Tang Xiangyang; Conover, David; Yu Rongfeng

    2003-01-01

    Cone beam computed tomography (CBCT) has been investigated in the past two decades due to its potential advantages over a fan beam CT. These advantages include (a) great improvement in data acquisition efficiency, spatial resolution, and spatial resolution uniformity, (b) substantially better utilization of x-ray photons generated by the x-ray tube compared to a fan beam CT, and (c) significant advancement in clinical three-dimensional (3D) CT applications. However, most studies of CBCT in the past are focused on cone beam data acquisition theories and reconstruction algorithms. The recent development of x-ray flat panel detectors (FPD) has made CBCT imaging feasible and practical. This paper reports a newly built flat panel detector-based CBCT prototype scanner and presents the results of the preliminary evaluation of the prototype through a phantom study. The prototype consisted of an x-ray tube, a flat panel detector, a GE 8800 CT gantry, a patient table and a computer system. The prototype was constructed by modifying a GE 8800 CT gantry such that both a single-circle cone beam acquisition orbit and a circle-plus-two-arcs orbit can be achieved. With a circle-plus-two-arcs orbit, a complete set of cone beam projection data can be obtained, consisting of a set of circle projections and a set of arc projections. Using the prototype scanner, the set of circle projections were acquired by rotating the x-ray tube and the FPD together on the gantry, and the set of arc projections were obtained by tilting the gantry while the x-ray tube and detector were at the 12 and 6 o'clock positions, respectively. A filtered backprojection exact cone beam reconstruction algorithm based on a circle-plus-two-arcs orbit was used for cone beam reconstruction from both the circle and arc projections. The system was first characterized in terms of the linearity and dynamic range of the detector. Then the uniformity, spatial resolution and low contrast resolution were assessed using

  16. Independent peer review panel report on the integrated nonthermal treatment systems study and the comparison of integrated thermal and integrated nonthermal treatment systems for mixed low level waste

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    The US Department of Energy`s (DOE) Office of Environmental Management (EM) Office of Science and Technology (OST) has conducted studies of integrated thermal treatment systems and integrated nonthermal treatment systems (INTS) for treating contact handled, alpha and non-alpha mixed low level radioactive waste (MLLW). The MLLW in the DOE complex consists of a wide variety of organic and inorganic solids and liquids contaminated with radioactive substances. Treatment systems are needed to destroy organic material and stabilize residues prior to land disposal. In May 1996 the Deputy Assistant Secretary for OST appointed an Independent Peer Review Panel to: (1) review and comment on the INTS Study; (2) make recommendations on the most promising thermal and nonthermal treatment systems; (3) make recommendations on research and development necessary to prove the performance of nonthermal and thermal technologies; and (4) review and comment on the preliminary draft of the ITTS/INTS Comparison Report. This report presents the primary conclusions and recommendations based on the review of the INTS study and the comparison report. System selection, overviews, comparisons, cost estimations and sensitivity analyses, and recommended R and D engineering needs are then described and discussed.

  17. Independent peer review panel report on the integrated nonthermal treatment systems study and the comparison of integrated thermal and integrated nonthermal treatment systems for mixed low level waste

    International Nuclear Information System (INIS)

    1996-08-01

    The US Department of Energy's (DOE) Office of Environmental Management (EM) Office of Science and Technology (OST) has conducted studies of integrated thermal treatment systems and integrated nonthermal treatment systems (INTS) for treating contact handled, alpha and non-alpha mixed low level radioactive waste (MLLW). The MLLW in the DOE complex consists of a wide variety of organic and inorganic solids and liquids contaminated with radioactive substances. Treatment systems are needed to destroy organic material and stabilize residues prior to land disposal. In May 1996 the Deputy Assistant Secretary for OST appointed an Independent Peer Review Panel to: (1) review and comment on the INTS Study; (2) make recommendations on the most promising thermal and nonthermal treatment systems; (3) make recommendations on research and development necessary to prove the performance of nonthermal and thermal technologies; and (4) review and comment on the preliminary draft of the ITTS/INTS Comparison Report. This report presents the primary conclusions and recommendations based on the review of the INTS study and the comparison report. System selection, overviews, comparisons, cost estimations and sensitivity analyses, and recommended R and D engineering needs are then described and discussed

  18. FY 1998 annual summary report on comprehensive development study of high-function flat panel display techniques (second year); 1998 nendo koseino flat panel display gijutsu no sogo kaihatsu kenkyu seika hokokusho. Daininendo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This project is aimed at creation of the new world display industry in Shikoku by developing the high-function flat panel display techniques and thereby establishing new techniques which solve the problems involved in, e.g., LEDs, plasma-aided devices and ELs other than liquid crystal devices. For development of emitters using diamond, important results have been obtained for the morphology, and cathode luminescence, Raman and photoluminescence spectra of polycrystalline diamond, synthesized by the vapor-phase process under varying conditions, on the electron radiation characteristics of the emitters. These results have led to clarification of the optimum vapor-phase synthesis conditions for diamond for high-function emitters. The techniques utilizing focused ion beams have also advanced to develop thin polycrystalline diamond films for emitters which correspond to the image elements of quality for television. For electron emitters, a structure prepared by implantation without using a high electrical field is proposed, and the device mechanisms involved are clarified. (NEDO)

  19. Comprehensive Diagnostic Assessment of Health Status of Patients with Asthma or COPD : A Delphi Panel Study among Dutch Experts

    NARCIS (Netherlands)

    van den Akker, Edmée F M M; van't Hul, Alex J.; Birnie, Erwin; Chavannes, Niels H.; Rutten-van Mölken, Maureen P M H; In't Veen, Johannes C C M

    2017-01-01

    A comprehensive diagnostic assessment is needed to improve understanding of the health status of patients with chronic obstructive pulmonary disease (COPD) or asthma. Therefore, this study investigated which components and subsequent instruments should be part of a holistic assessment in secondary

  20. Do older workers develop a short-timer's attitude prior to retirement?: evidence from a panel study

    NARCIS (Netherlands)

    Damman, M.; Henkens, C.J.I.M.; Kalmijn, M.

    2011-01-01

    Objectives. Even though in retirement and career theories reference is made to a preretirement work disengagement process among older workers, quantitative empirical knowledge about this process is limited. The aim of this study is to improve our understanding of work disengagement in the